LOCUS       DAGQVA010000001       167214 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.001, whole genome shotgun sequence.
ACCESSION   DAGQVA010000001 DAGQVA010000000
VERSION     DAGQVA010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 167214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 167214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..167214
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.001"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(14..523)
                     /locus_tag="MIV85_000001"
     CDS             complement(14..523)
                     /locus_tag="MIV85_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBY2959383.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(734..2143)
                     /locus_tag="MIV85_000002"
     CDS             complement(734..2143)
                     /locus_tag="MIV85_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959384.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(2147..3277)
                     /locus_tag="MIV85_000003"
     CDS             complement(2147..3277)
                     /locus_tag="MIV85_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2959385.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(3289..4092)
                     /locus_tag="MIV85_000004"
     CDS             complement(3289..4092)
                     /locus_tag="MIV85_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959386.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(4474..5355)
                     /locus_tag="MIV85_000005"
     CDS             complement(4474..5355)
                     /locus_tag="MIV85_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBY2959387.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            5811..6785
                     /locus_tag="MIV85_000006"
     CDS             5811..6785
                     /locus_tag="MIV85_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959388.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(6901..7962)
                     /locus_tag="MIV85_000007"
     CDS             complement(6901..7962)
                     /locus_tag="MIV85_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBY2959389.1"
                     /translation="MKKIRKLTTKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(8574..9425)
                     /locus_tag="MIV85_000008"
     CDS             complement(8574..9425)
                     /locus_tag="MIV85_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2959390.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(9442..10362)
                     /locus_tag="MIV85_000009"
     CDS             complement(9442..10362)
                     /locus_tag="MIV85_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBY2959391.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(10472..11386)
                     /gene="murQ"
                     /locus_tag="MIV85_000010"
     CDS             complement(10472..11386)
                     /gene="murQ"
                     /locus_tag="MIV85_000010"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBY2959392.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(11485..12582)
                     /locus_tag="MIV85_000011"
     CDS             complement(11485..12582)
                     /locus_tag="MIV85_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBY2959393.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKRINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDIGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(12815..14161)
                     /locus_tag="MIV85_000012"
     CDS             complement(12815..14161)
                     /locus_tag="MIV85_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2959394.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPELLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(14250..14558)
                     /locus_tag="MIV85_000013"
     CDS             complement(14250..14558)
                     /locus_tag="MIV85_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2959395.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(14820..15218)
                     /locus_tag="MIV85_000014"
     CDS             complement(14820..15218)
                     /locus_tag="MIV85_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959396.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(15220..16380)
                     /locus_tag="MIV85_000015"
     CDS             complement(15220..16380)
                     /locus_tag="MIV85_000015"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBY2959397.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(16811..17830)
                     /locus_tag="MIV85_000016"
     CDS             complement(16811..17830)
                     /locus_tag="MIV85_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2959398.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRNNTMFEDVFINKFNLEKLIKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(17824..18504)
                     /locus_tag="MIV85_000017"
     CDS             complement(17824..18504)
                     /locus_tag="MIV85_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2959399.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVGLIDDFEVVLDEFIDR
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(18656..20563)
                     /locus_tag="MIV85_000018"
     CDS             complement(18656..20563)
                     /locus_tag="MIV85_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBY2959400.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNVYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(20564..21316)
                     /locus_tag="MIV85_000019"
     CDS             complement(20564..21316)
                     /locus_tag="MIV85_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2959401.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(21632..22786)
                     /locus_tag="MIV85_000020"
     CDS             complement(21632..22786)
                     /locus_tag="MIV85_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2959402.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(22789..23256)
                     /locus_tag="MIV85_000021"
     CDS             complement(22789..23256)
                     /locus_tag="MIV85_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2959403.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(23270..23758)
                     /locus_tag="MIV85_000022"
     CDS             complement(23270..23758)
                     /locus_tag="MIV85_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959404.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSSF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(23772..25103)
                     /locus_tag="MIV85_000023"
     CDS             complement(23772..25103)
                     /locus_tag="MIV85_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBY2959405.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     DRQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(25117..26682)
                     /locus_tag="MIV85_000024"
     CDS             complement(25117..26682)
                     /locus_tag="MIV85_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2959406.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(26852..27637)
                     /locus_tag="MIV85_000025"
     CDS             complement(26852..27637)
                     /locus_tag="MIV85_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2959407.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(27804..29003)
                     /locus_tag="MIV85_000026"
     CDS             complement(27804..29003)
                     /locus_tag="MIV85_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBY2959408.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEEMSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYIDTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKQYTNARNIKLNPVENLPTSVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(29525..30862)
                     /gene="xylA"
                     /locus_tag="MIV85_000027"
     CDS             complement(29525..30862)
                     /gene="xylA"
                     /locus_tag="MIV85_000027"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBY2959409.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(30958..32508)
                     /gene="xylB"
                     /locus_tag="MIV85_000028"
     CDS             complement(30958..32508)
                     /gene="xylB"
                     /locus_tag="MIV85_000028"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBY2959410.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            32716..33876
                     /locus_tag="MIV85_000029"
     CDS             32716..33876
                     /locus_tag="MIV85_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBY2959411.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(34032..34436)
                     /locus_tag="MIV85_000030"
     CDS             complement(34032..34436)
                     /locus_tag="MIV85_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2959412.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(34457..34939)
                     /locus_tag="MIV85_000031"
     CDS             complement(34457..34939)
                     /locus_tag="MIV85_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2959413.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(34959..35768)
                     /locus_tag="MIV85_000032"
     CDS             complement(34959..35768)
                     /locus_tag="MIV85_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBY2959414.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(35761..36540)
                     /locus_tag="MIV85_000033"
     CDS             complement(35761..36540)
                     /locus_tag="MIV85_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2959415.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(36540..38618)
                     /locus_tag="MIV85_000034"
     CDS             complement(36540..38618)
                     /locus_tag="MIV85_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBY2959416.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(39417..39938)
                     /locus_tag="MIV85_000035"
     CDS             complement(39417..39938)
                     /locus_tag="MIV85_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBY2959417.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            40104..40670
                     /locus_tag="MIV85_000036"
     CDS             40104..40670
                     /locus_tag="MIV85_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBY2959418.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTIGTVLGAVV
                     LGPFWSALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(40887..42950)
                     /locus_tag="MIV85_000037"
     CDS             complement(40887..42950)
                     /locus_tag="MIV85_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBY2959419.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(43331..46666)
                     /locus_tag="MIV85_000038"
     CDS             complement(43331..46666)
                     /locus_tag="MIV85_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBY2959420.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKTETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(46716..47144)
                     /locus_tag="MIV85_000039"
     CDS             complement(46716..47144)
                     /locus_tag="MIV85_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959421.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(47134..47514)
                     /locus_tag="MIV85_000040"
     CDS             complement(47134..47514)
                     /locus_tag="MIV85_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBY2959422.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYKSKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(47547..47855)
                     /locus_tag="MIV85_000041"
     CDS             complement(47547..47855)
                     /locus_tag="MIV85_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959423.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(47900..49060)
                     /locus_tag="MIV85_000042"
     CDS             complement(47900..49060)
                     /locus_tag="MIV85_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBY2959424.1"
                     /translation="MEYRLNEVFEFIRNGASIKQFDTKFGYPITRIETIANSYIDTNK
                     MGYADIKELGKLEDYLLKNGDILMSHINSEKHLGKSAIYEDINKKIIHGMNLLCLRPD
                     KEVCYPKYLNYFFNSNEFRRQLPRIIKKSVNQASFSVNDLKNLKVDLPEMEAQKDISK
                     VLDKAQELIDKRKEQIEALDELVKSRFIEMFGNFKEQKFVLLKDCTNFIDYRGKTPIL
                     SENGIRIINAKSVGNGVFKYINEYISENTYNSWMKRGFPVAGDVLFVTEGHTFGNVCR
                     IPKDLKKFAMGQRIITIQGDKKILNNAFLAQYMQTKAFRVEIDKYKTGSSAQGIRSKE
                     LQKILIPVPSIELQNKFEEFVNQVDKLKVGIKTSLKELEDNFNSLMQKAFKG"
     gene            complement(49064..50527)
                     /locus_tag="MIV85_000043"
     CDS             complement(49064..50527)
                     /locus_tag="MIV85_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBY2959425.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIVDGLEELERMLEV"
     gene            complement(51036..51905)
                     /gene="gatY"
                     /locus_tag="MIV85_000044"
     CDS             complement(51036..51905)
                     /gene="gatY"
                     /locus_tag="MIV85_000044"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBY2959426.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(51925..53841)
                     /locus_tag="MIV85_000045"
     CDS             complement(51925..53841)
                     /locus_tag="MIV85_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2959427.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKRKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGL
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(53844..54764)
                     /locus_tag="MIV85_000046"
     CDS             complement(53844..54764)
                     /locus_tag="MIV85_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBY2959428.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWLEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(54866..55618)
                     /locus_tag="MIV85_000047"
     CDS             complement(54866..55618)
                     /locus_tag="MIV85_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2959429.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(56010..57455)
                     /locus_tag="MIV85_000048"
     CDS             complement(56010..57455)
                     /locus_tag="MIV85_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBY2959430.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            complement(57477..57830)
                     /locus_tag="MIV85_000049"
     CDS             complement(57477..57830)
                     /locus_tag="MIV85_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBY2959431.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(57859..59106)
                     /locus_tag="MIV85_000050"
     CDS             complement(57859..59106)
                     /locus_tag="MIV85_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2959432.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFTVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(59114..59431)
                     /locus_tag="MIV85_000051"
     CDS             complement(59114..59431)
                     /locus_tag="MIV85_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2959433.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            59673..61586
                     /locus_tag="MIV85_000052"
     CDS             59673..61586
                     /locus_tag="MIV85_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2959434.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     DLFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(61709..62863)
                     /locus_tag="MIV85_000053"
     CDS             complement(61709..62863)
                     /locus_tag="MIV85_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBY2959435.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKDTIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(63123..65738)
                     /gene="mngB"
                     /locus_tag="MIV85_000054"
     CDS             complement(63123..65738)
                     /gene="mngB"
                     /locus_tag="MIV85_000054"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBY2959436.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(65882..67807)
                     /gene="mngA"
                     /locus_tag="MIV85_000055"
     CDS             complement(65882..67807)
                     /gene="mngA"
                     /locus_tag="MIV85_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBY2959437.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AVLLIITRKQKNQRKIH"
     gene            complement(67937..68662)
                     /locus_tag="MIV85_000056"
     CDS             complement(67937..68662)
                     /locus_tag="MIV85_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2959438.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEVAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(68925..69695)
                     /locus_tag="MIV85_000057"
     CDS             complement(68925..69695)
                     /locus_tag="MIV85_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBY2959439.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(69697..71124)
                     /locus_tag="MIV85_000058"
     CDS             complement(69697..71124)
                     /locus_tag="MIV85_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2959440.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGVRLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            71515..72237
                     /locus_tag="MIV85_000059"
     CDS             71515..72237
                     /locus_tag="MIV85_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2959441.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            72434..74101
                     /locus_tag="MIV85_000060"
     CDS             72434..74101
                     /locus_tag="MIV85_000060"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBY2959442.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYYLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(74197..75516)
                     /locus_tag="MIV85_000061"
     CDS             complement(74197..75516)
                     /locus_tag="MIV85_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBY2959443.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRQTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(75557..76303)
                     /locus_tag="MIV85_000062"
     CDS             complement(75557..76303)
                     /locus_tag="MIV85_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBY2959444.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(76547..78556)
                     /locus_tag="MIV85_000063"
     CDS             complement(76547..78556)
                     /locus_tag="MIV85_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2959445.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(78950..80383)
                     /locus_tag="MIV85_000064"
     CDS             complement(78950..80383)
                     /locus_tag="MIV85_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBY2959446.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(80470..82386)
                     /locus_tag="MIV85_000065"
     CDS             complement(80470..82386)
                     /locus_tag="MIV85_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2959447.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGVFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(82460..83320)
                     /locus_tag="MIV85_000066"
     CDS             complement(82460..83320)
                     /locus_tag="MIV85_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2959448.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(83671..84858)
                     /locus_tag="MIV85_000067"
     CDS             complement(83671..84858)
                     /locus_tag="MIV85_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2959449.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(84872..86263)
                     /locus_tag="MIV85_000068"
     CDS             complement(84872..86263)
                     /locus_tag="MIV85_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBY2959450.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIAPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(86858..88558)
                     /locus_tag="MIV85_000069"
     CDS             complement(86858..88558)
                     /locus_tag="MIV85_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2959451.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(88530..89933)
                     /locus_tag="MIV85_000070"
     CDS             complement(88530..89933)
                     /locus_tag="MIV85_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2959452.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(90197..90688)
                     /locus_tag="MIV85_000071"
     CDS             complement(90197..90688)
                     /locus_tag="MIV85_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2959453.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(90714..91526)
                     /locus_tag="MIV85_000072"
     CDS             complement(90714..91526)
                     /locus_tag="MIV85_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBY2959454.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLSKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(91539..92690)
                     /locus_tag="MIV85_000073"
     CDS             complement(91539..92690)
                     /locus_tag="MIV85_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBY2959455.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEVAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            92960..93601
                     /locus_tag="MIV85_000074"
     CDS             92960..93601
                     /locus_tag="MIV85_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBY2959456.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            93627..95171
                     /locus_tag="MIV85_000075"
     CDS             93627..95171
                     /locus_tag="MIV85_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2959457.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(95371..95997)
                     /locus_tag="MIV85_000076"
     CDS             complement(95371..95997)
                     /locus_tag="MIV85_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBY2959458.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(96132..96848)
                     /locus_tag="MIV85_000077"
     CDS             complement(96132..96848)
                     /locus_tag="MIV85_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBY2959459.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDKAATKFGLE"
     gene            97274..98488
                     /locus_tag="MIV85_000078"
     CDS             97274..98488
                     /locus_tag="MIV85_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBY2959460.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            99108..100436
                     /locus_tag="MIV85_000079"
     CDS             99108..100436
                     /locus_tag="MIV85_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959461.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINHLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(100564..101754)
                     /locus_tag="MIV85_000080"
     CDS             complement(100564..101754)
                     /locus_tag="MIV85_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2959462.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSKNGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGSVPNAIPNKASMSGTLRTFDQSVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(101860..103239)
                     /locus_tag="MIV85_000081"
     CDS             complement(101860..103239)
                     /locus_tag="MIV85_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2959463.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(103270..104478)
                     /locus_tag="MIV85_000082"
     CDS             complement(103270..104478)
                     /locus_tag="MIV85_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959464.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIIPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            complement(105503..106957)
                     /locus_tag="MIV85_000083"
     CDS             complement(105503..106957)
                     /locus_tag="MIV85_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBY2959465.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKIGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            complement(106977..108848)
                     /locus_tag="MIV85_000084"
     CDS             complement(106977..108848)
                     /locus_tag="MIV85_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2959466.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            complement(108838..109698)
                     /locus_tag="MIV85_000085"
     CDS             complement(108838..109698)
                     /locus_tag="MIV85_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2959467.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKASDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            complement(110293..110697)
                     /locus_tag="MIV85_000086"
     CDS             complement(110293..110697)
                     /locus_tag="MIV85_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBY2959468.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPLIYLKYKPDK"
     gene            complement(110889..112076)
                     /locus_tag="MIV85_000087"
     CDS             complement(110889..112076)
                     /locus_tag="MIV85_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBY2959469.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(112108..112533)
                     /locus_tag="MIV85_000088"
     CDS             complement(112108..112533)
                     /locus_tag="MIV85_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959470.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            112991..113740
                     /locus_tag="MIV85_000089"
     CDS             112991..113740
                     /locus_tag="MIV85_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBY2959471.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(113906..114271)
                     /locus_tag="MIV85_000090"
     CDS             complement(113906..114271)
                     /locus_tag="MIV85_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBY2959472.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(114287..115063)
                     /locus_tag="MIV85_000091"
     CDS             complement(114287..115063)
                     /locus_tag="MIV85_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2959473.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(115510..116937)
                     /gene="ascB"
                     /locus_tag="MIV85_000092"
     CDS             complement(115510..116937)
                     /gene="ascB"
                     /locus_tag="MIV85_000092"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBY2959474.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(116998..118926)
                     /locus_tag="MIV85_000093"
     CDS             complement(116998..118926)
                     /locus_tag="MIV85_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2959475.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(119071..119913)
                     /locus_tag="MIV85_000094"
     CDS             complement(119071..119913)
                     /locus_tag="MIV85_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2959476.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(120260..121630)
                     /locus_tag="MIV85_000095"
     CDS             complement(120260..121630)
                     /locus_tag="MIV85_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2959477.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQDVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            complement(121669..122340)
                     /gene="pgmB"
                     /locus_tag="MIV85_000096"
     CDS             complement(121669..122340)
                     /gene="pgmB"
                     /locus_tag="MIV85_000096"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBY2959478.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            complement(122342..124732)
                     /locus_tag="MIV85_000097"
     CDS             complement(122342..124732)
                     /locus_tag="MIV85_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBY2959479.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVEDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSVGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(124758..126206)
                     /locus_tag="MIV85_000098"
     CDS             complement(124758..126206)
                     /locus_tag="MIV85_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBY2959480.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMIIGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(126609..127496)
                     /locus_tag="MIV85_000099"
     CDS             complement(126609..127496)
                     /locus_tag="MIV85_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2959481.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(127596..128045)
                     /locus_tag="MIV85_000100"
     CDS             complement(127596..128045)
                     /locus_tag="MIV85_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2959482.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNANTKKEILDIFYEV"
     gene            complement(128035..129942)
                     /locus_tag="MIV85_000101"
     CDS             complement(128035..129942)
                     /locus_tag="MIV85_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2959483.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVSTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(130210..132105)
                     /locus_tag="MIV85_000102"
     CDS             complement(130210..132105)
                     /locus_tag="MIV85_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2959484.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(132141..133019)
                     /locus_tag="MIV85_000103"
     CDS             complement(132141..133019)
                     /locus_tag="MIV85_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBY2959485.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(133724..135157)
                     /locus_tag="MIV85_000104"
     CDS             complement(133724..135157)
                     /locus_tag="MIV85_000104"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBY2959486.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVVENPYLKISDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
     gene            complement(135180..137021)
                     /locus_tag="MIV85_000105"
     CDS             complement(135180..137021)
                     /locus_tag="MIV85_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2959487.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLSANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDIISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            complement(137147..137980)
                     /locus_tag="MIV85_000106"
     CDS             complement(137147..137980)
                     /locus_tag="MIV85_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2959488.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            complement(139023..139235)
                     /locus_tag="MIV85_000107"
     CDS             complement(139023..139235)
                     /locus_tag="MIV85_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959489.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(139236..139652)
                     /locus_tag="MIV85_000108"
     CDS             complement(139236..139652)
                     /locus_tag="MIV85_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959490.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(139722..140135)
                     /locus_tag="MIV85_000109"
     CDS             complement(139722..140135)
                     /locus_tag="MIV85_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959491.1"
                     /translation="MSKSELGVKANLVSELMMLSYFFIDLLLQKFIFKGEGIWFTFII
                     LLAFWVCNLMYNKKYNDLVDEASKLMLLKVDQIASKIMLYSMFVIAVLFSVNHTRALD
                     ISNLDIGIMLLAVLFIQSLSKLILYIYFDKKGICN"
     gene            complement(140969..141598)
                     /locus_tag="MIV85_000110"
     CDS             complement(140969..141598)
                     /locus_tag="MIV85_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBY2959492.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDVRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(141677..142639)
                     /locus_tag="MIV85_000111"
     CDS             complement(141677..142639)
                     /locus_tag="MIV85_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBY2959493.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQNQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(143401..147099)
                     /gene="cbpA"
                     /locus_tag="MIV85_000112"
     CDS             complement(143401..147099)
                     /gene="cbpA"
                     /locus_tag="MIV85_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBY2959494.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAEGDTNAGNAEGDTNAGNAGGDANAGNAGGDANAGNAGGDANAGNAGGD
                     ANAGNAEEDSNAGNAEGDANAGNAEEDANAGNAEEDSNAGNAEEDMNALVVEEATAED
                     PTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAEL
                     IFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLT
                     IDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYY
                     SAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGTIT
                     AKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFG
                     DGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLG
                     GAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDDQG
                     VLYLWFSDQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQYEEFTIDDT
                     PPYLIIKRYDGLPFEEDVEKLFLDWILKDGGIPIITPKGEKLTDKKFMTISSQRLNEE
                     TMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYKAEIIPADTE
                     TSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYINRKEYKDPVE
                     LKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLK
                     LDMTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGN
                     GDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPN
                     LNKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGN
                     GGNSKPDPDNGGNSKPDPDNGGNGKPDPDNGGNSKPDPDNGGNSKPDPDNGGNSKPDI
                     DTDGDGKPNINIDIDGDGKPDINIDTDGDGKPDINIDIDGDGKPDINIDIDGDGKPDI
                     NIDIDGDGKPDINIDTDGDGKPDINIDTDGNGKPDINIDTDESLDSNVGQNVQTGDQS
                     NIMLDLALMFISLFFLIKNLTNKYLRRK"
     gene            147368..147940
                     /locus_tag="MIV85_000113"
     CDS             147368..147940
                     /locus_tag="MIV85_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HBY2959495.1"
                     /translation="MEKLVKILINIICIIALTFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNINYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNDEFKYSLNYIT"
     gene            complement(148940..150565)
                     /locus_tag="MIV85_000114"
     CDS             complement(148940..150565)
                     /locus_tag="MIV85_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBY2959496.1"
                     /translation="MYNVIDLFAGAGGLSLGFEMTKKFNMVAFVEKNDNAAKTYLENH
                     PSVKRYCDIKRLDFQDILNSVDKIDVVIGGPPCQGFSNANRQKRKIINGNNELVKLYV
                     DAIDKLKPNVFVMENVKTISSNKHSFYLTKKDKNHIINNLKLNIYNKDSVLYDRTEYI
                     NELFNIISIEDIESYIISNIDLKNLKIIIKKKKDICDYLNKISNYKKVKSTIEKLETR
                     GKMPKWYLELINKVKNILENMLYNRNLSDEQIFYLNLFLDIQNLFLGIYELKSESVIF
                     ENTLDDNKIIAKMDTYIIIDYINASFEYLGYVLNGSALNSIDYGVPQNRERFVLIGAK
                     KDFLKNKKIETPKPIVGENYVTVRDAIGDLAEYEASKGSMDYCFEKNSNNIEKDFYRK
                     IILDSNKIYNHVCTDTRNIALKRFEYINQGNNFHSLPDELKGTYADPERTQNTIYKRL
                     VYDKPSDTVVNVRKSMWIHPIKNRAVSAREAARLQSFPDSYKFLGTKDSVYQQIGNAV
                     PPLLGRVVAEKILNLFNDEPNEYLRDVFEALDG"
     gene            150877..153495
                     /locus_tag="MIV85_000115"
     CDS             150877..153495
                     /locus_tag="MIV85_000115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959497.1"
                     /translation="MLTTNIHYILDNDICEIYFNKQRLTNSKYYQDNINVLNYIINEK
                     NNNLIINYNDKYIYAIYLLNIAINSYLNNTLNPNNHILTKLDKGMPLLYKGQIVIFKN
                     INNTHITLGHKNKTDTTLIPIDSAYMLITYNGHLEVNSMGKTPASKTFQTKNVLSSLG
                     FSDLKNMTGVINDSTLIILPCKDDISDLVSNIKIKDINNTYKFTELFPCSYISSTGAE
                     TDYPGNHAKQIPLLKFTTNISSAFEIIKSDKSIKNVFIIGDYPIYKHINDFERILNRK
                     RIESVNIVTSNSNISNILDLPNIDNLNIYSWSKDVLLTYSQDFENTSTFQKLWLDKLI
                     NKNICTTSVDSNISDLIHQARKSLYYISKYDFDISIKNSLMMCSYSLLKILENTPFNL
                     DFLEETIKLLNLNIATPSAKLENIKYLISSTSPDLELSALFDDVIVKFERIINELSDN
                     NTKFNTLNKLVSSYKYKTFTPNTPVILLQKQYEAIILKNLLKSRNINLQVISAEKFKD
                     SKTIKNLIMFGFYDLKYLDILNSDLIINITLYLYNSELSKYNYYMNQINSARNKIEKN
                     NKIYNLLDIKPFKPTYETNKLEAYSTDSPISDDDSMDEYISNYKFDINLNEIILSLSI
                     NQGIYNSKKEHVTSFMISDNNEYIFCTKKAIAYSIDWDKKSVRKKKLSEAKVNDWFLF
                     VDDYLNEEGELVINVIQKLLELNLLPSHYLDDYKLTNSWKSELKNYISYSKYNYNDVS
                     NSLAVLGEKINPITIKNWVTNKRLIGPIYLKTFEKIFKVIDSKLDHTEVYDATKSIRS
                     LHTKIKKSIDTFVSDNFFSSKSDIIKDEVSAVVLSMLGNTNDYVTPVQIREIHSCDKY
                     LSPHLVNKVLDLYSVY"
     gene            153513..157040
                     /locus_tag="MIV85_000116"
     CDS             153513..157040
                     /locus_tag="MIV85_000116"
                     /inference="COORDINATES: protein motif:HMM:NF012493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBY2959498.1"
                     /translation="MNCSELRDKTLDLVRKELLGPGSEDLCENIKYEIITDSPIERYS
                     TGILYPLNNNIDVSNTSEYDGEDNVFTSDDTQNELDRAISMSNETLPSSMGMTFFLKK
                     DAEVINFRVNYATYRNALYTDCHVKYTGDDFYSSNTINEYVELRGSFLYLKQKLTSEK
                     VYNLLKKHDLLDNAEAKFVLYKLANQCPDDENKTGGYVRVPHENLIVSIDMDKNYIKK
                     PISKDLDIVLSKRIYSNDFVSITCMLVNSQSGPKKYNNTIFQPELMVLAEDNNDLEFI
                     DIFTAGSVNTFKKLDSEEISLDLLYRNKKTFATGHGVAIDQDIQNDALIKLCTEFIPH
                     FEVPKLDFNVDELSDVSRELLSMKNLSDISDLSKDKKIYFLYKFVDAYDIWIDDLEED
                     SKDLSDVFKDVAYEHIKNCRDTKSRMLEGINLIKSNDEVYRAFSLMNRAILMQRCHSI
                     HITDRLPGSNNLDYIDYSNDNSAWRPFQLAYILTCLSSIENPDSKHRDLVDLLWIPTG
                     GGKTEAYLGLSAFTIFLRRIRNKENGNGTAIIMRYTLRLLAAQQFIRASILICACEII
                     RKENKSELGKKEISIGLWIGSDQTPNFNDEAEEMLNNLTGNNIKFRSSINSEYELDNL
                     KSKYNKFQLLKCPWCGTKLVKEWDKTSKKAVGDWGYRIKSRPKKFYLCCPEEDCSFED
                     MLPIQVVDEEIYNNPPTLLFGTVDKFAMITWTTEVASLFALDDDNSNLSPELIIQDEL
                     HLISGPLGTMVGLYETALDAMCSYKGIKPKIIASTATIRKAQNQVKNLYNRNVAQFPP
                     PGLTSSNSFFVKEMPLSKKRGRLYVGVIPSGKTQVTVEVRLMSALLQRLKMMENVELN
                     LLDKYWTLVSYFNSIRELGKCSTLLNDDIKDNMERLCKRVSAHPYQSLRNLNEQRELT
                     SRLTSTKINTTLDELSNTLTSNNLTVDTLLASNMISVGVDVDRLNLMVVVGQPKLTSE
                     YIQASSRVGRSNEGLIFTLYNPTKTRDRSHYEQFFSYHQSFYKFVEPTSITPFSEPAR
                     ERGMHAVLISMIRHILGLQANDLASRFSKNMDGVEDLKNFIIDRSIDIFRENNQNADD
                     NIVNEFKSEISSELDIIMDLWHDKAQISDKDNLLHYYKRPSKFDNKIYNNLLIPYDKD
                     VITNEKQTLNSMRNVDKQCTVEIIELEEN"
     gene            157042..158955
                     /locus_tag="MIV85_000117"
     CDS             157042..158955
                     /locus_tag="MIV85_000117"
                     /inference="COORDINATES: protein motif:HMM:NF020926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HBY2959499.1"
                     /translation="MSIKLDDKTHNLRINQATSVFGPGAMLDFIDQTLMTAHPNYWTN
                     TIKIQDDRLQATLRVNELRTPPTIDDRSSVPFVRFPRWYFCPKCRKFMPIEDWEKLYK
                     NAHKDKPMKIPICLTCSTKKSTKQLVPTGIITICEHGHIDDFPWVKWVHFRNKSGRKE
                     ICENPQILMKTGKSNLGLEGIELECSCGAKANMKGAFMRLKSSKSNDYGVPSEYKEMF
                     KCSGNSPWYNKKVNKCTKYSFASQRGASNVYYPKIESSIIIPPYSDTLNSKVLSSKGY
                     DTFKKFLDRAIKKNKLERFMDEDFEDFASDIAKETGFDTDKVSIVLKDLLPFEDSSPS
                     TTTRNQYREEEYEALIGNIDAKSKKTNDFTIEEQNLSDYDIPNFSKIVLVKRLREVRA
                     LTGFSRVNPPDNNIFGEEDIDDSCNDTKVISLRSRDCKKSFYPASEVRGEGIFIEINN
                     DMVKSWISSNPKIQDNASILNSRYNKDINVNDKAYRKITPKFLLLHTLAHLIIRELSF
                     VCGYATSSLRERIYCNNSENEKVMSGILVYTASGDSEGTLGGLVRQGMHDSLPSILNS
                     ALNRALWCSNDPICIDSTGQGRNSLNLGACHSCTLLPETSCEEYNLLLDRSMLIGDMD
                     NRDIGFFKNLILI"
     gene            complement(159661..160404)
                     /locus_tag="MIV85_000118"
     CDS             complement(159661..160404)
                     /locus_tag="MIV85_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959500.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKKIKIKFGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(160426..160740)
                     /locus_tag="MIV85_000119"
     CDS             complement(160426..160740)
                     /locus_tag="MIV85_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959501.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            complement(160744..160944)
                     /locus_tag="MIV85_000120"
     CDS             complement(160744..160944)
                     /locus_tag="MIV85_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959502.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            161091..161852
                     /locus_tag="MIV85_000121"
     CDS             161091..161852
                     /locus_tag="MIV85_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959503.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYLLQSLFPEEYYSFDEFLNAISNLME
                     DDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDIK
                     EIIKNDVLTKQSIDELLDIGLSEESIETIYDYFSDSTDNGSNIRLKKLISQKENITIK
                     NNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            161909..162107
                     /locus_tag="MIV85_000122"
                     /pseudo
     CDS             161909..162107
                     /locus_tag="MIV85_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            162104..162595
                     /locus_tag="MIV85_000123"
     CDS             162104..162595
                     /locus_tag="MIV85_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2959504.1"
                     /translation="MMNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRM
                     PSLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVIHILENYGYDI
                     KTDYKKKFEITDNADTIKPINLNFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            162687..163439
                     /locus_tag="MIV85_000124"
     CDS             162687..163439
                     /locus_tag="MIV85_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBY2959505.1"
                     /translation="MNKSYIPKYTHKFPTNIPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILINNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            163429..164595
                     /locus_tag="MIV85_000125"
     CDS             163429..164595
                     /locus_tag="MIV85_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBY2959506.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPLRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKYLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQGPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYINNNYVFCNELGIPIDDKRPLRNLKSILNSLNIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(164711..164941)
                     /locus_tag="MIV85_000126"
     CDS             complement(164711..164941)
                     /locus_tag="MIV85_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959507.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(164947..165426)
                     /locus_tag="MIV85_000127"
     CDS             complement(164947..165426)
                     /locus_tag="MIV85_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HBY2959508.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFDSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            complement(165426..165641)
                     /locus_tag="MIV85_000128"
     CDS             complement(165426..165641)
                     /locus_tag="MIV85_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBY2959509.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            complement(165973..166322)
                     /gene="ssrA"
                     /locus_tag="MIV85_000129"
     tmRNA           complement(165973..166322)
                     /gene="ssrA"
                     /locus_tag="MIV85_000129"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(166480..166935)
                     /gene="smpB"
                     /locus_tag="MIV85_000130"
     CDS             complement(166480..166935)
                     /gene="smpB"
                     /locus_tag="MIV85_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBY2959510.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
BASE COUNT        55379 a        28825 c        18267 g        64743 t
ORIGIN      
        1 atactaaaac actttattga ggtatatgac ttgaaatata tgaactaact tcattaggag
       61 aaatatctaa aatagttgca aattcttcat ttaataacct ttcagcttct ttcattatat
      121 tatcatctgc ttgatgtgtt tttttaccaa tagattttac atactctctg ttattatcta
      181 tacttcttac taattttatt aactcttcac atttaccacc tctgagtatt tttttaaatt
      241 gctcacttct caatttttca ttatctatcc atgatgtatc catattagga atatcattta
      301 ttaatgaaag cacattaatt ttagaaagta actttctcat tggtactttt tcattatcta
      361 caggaatttt tattactgta ttattagaat aaataggact caatacataa tactcttttt
      421 ttattccatt tgtaaatcgt tcatttgtta tatccatgac tttgcagact cctgtcatac
      481 catacattat ataatcatca atcttaaaca aaaacatcac catccttaat aaaaaaaata
      541 gttttgacaa ctaaatccac cttgccaaaa ctatctgcta tatattatat tttaacacat
      601 tttaagactt aaatgtaagt aaaacttata ttattaaaat taaaaaatac attaaccatt
      661 gattaatgta ttttttagat ttttataaca agcatatcaa aataaattaa tacagcttat
      721 ctcctgtgaa tacctataaa attggtgctt ggctattcat tgagtaccca tcatttctta
      781 catcatttat ttctaatatt tcatcatttg ttttaacctt agtaagtttt ttaactgctc
      841 cataaggttc ttttaatgaa attttatctc ctcttccaga aataacccat aaaattttat
      901 accctctagg tattacttgt agtttatttt cacctttacc atcagtaaag tagactaaca
      961 aattaatctt tttattatta gcatactcaa agactggaga aaatctagta cctccaccta
     1021 tcctaattct atcttttata tctttttcag ttctcacttt atatacacgt ctaatttcat
     1081 tatcacattc tataattgta atttcatgat tatagttttt cactatacta agaacttctt
     1141 taatagcttg tttaaactct tcatcactaa tacttccact tacatcaagt gcaactgcta
     1201 tttctgactt atgacttcta agttctcccc tcaaatctaa acgatttggt tgtcttctat
     1261 ttcttcttgt tatagtcttc tttttattat tttcaactgt tcccattatt ctattaagat
     1321 ataaattcca tggcaattca cccttactat ttttaagtga tgatatcata ctttctaaat
     1381 aagcaggaac tttacctttt tgagaactgt taataaattt ttcagtaaat tctctaaggg
     1441 tattttcatc tatctcattg gattcatccc atatatcatg agttctttcg gggctataat
     1501 caatttctat atctccatat ttatcactat catcttcctc accatcttca tccacttcca
     1561 tcaaatctaa ttcagtctga atcttttcta cataatattc aaaaggttca tatggttcaa
     1621 gttttaagga atactttaaa tttacccact ctaaggtagt tgcatatggt ggtaaattgt
     1681 ttagaaattt atttactact atatccattg ccatattaat tgctaatgta ctatactttc
     1741 cttttaactc ctttgctctc atcaaatgca tagataatat atgatgaatt tcatgtttaa
     1801 ttgtagtctc catttgcttt atgtcaagcg ttaaaaagat tattggatta aaatatataa
     1861 catatttagc tcccttaaaa ttcacacctg taggactact tatatcaaat cttatttctc
     1921 ttgacatctg aaacaaaaaa tatccataaa aattatcttc ttcttccata agacttaaat
     1981 tcactttatc tacaagacta aaaaactcat acttaaaatc ttgtggtata tctatatcaa
     2041 atttctcatt agcacgattt gcctttagca tagaatgagt atttataatt tcacttgctt
     2101 tattataaag ctcttttgct tgtttatcaa aataattttc catacattat ccccttatta
     2161 aactataaga ttcaaaatat gattttacaa actcttcatt ttctatagct tttttatata
     2221 cttcaatata actgtttcta atatccttca taatacctat cattaaatct acaggataca
     2281 tttttaaaaa ttcaataaat ctattaatat agtggtttga ttcatattta tcattcttaa
     2341 tatttaattc taagtctttt agaatgttca tagctgatag ataaagtctt gtatgactct
     2401 cattttttac tctttctaca atagactcat caatagattc tcctaaaaaa acatcttcat
     2461 aggatattaa tggttcagag tttgattcaa taaaacttat aaattcttct gcaataactt
     2521 tacctacatt accctttaca acatttaaaa atactgctct aggaatagaa ttattttttt
     2581 ctttataaac tttataaatt ttagatactc tctcataact tctaggagtg gctcttacat
     2641 catcttcatt tattttatgc agatattctg gaaaagtgga aataaactcg ataacttttc
     2701 tttcaatacc ctcatctatt gcccatttta tccattgtgt atggtcactc tccatattta
     2761 accaaacaaa cctattttct tgggctgcat ccatatctac cacttgataa tcaaaatctg
     2821 aaccatattt acttgatgga ttcattgctg ctaaaatctt tacatcatca tgcagtttat
     2881 atccattaat ttctctattt aaaattaaat tcataagttc ttgctgtact gtatgctcac
     2941 aacgatttat ctcatctata aataaaagaa ctgtcttact tttagatatc tcttcatcaa
     3001 tttctcttaa tttgttatga acagcataca ctgttgtttt cttttcagtc ttatatccat
     3061 tagaattaac tcctacataa gattctatag ttggaagacc acctatttca ccctctttaa
     3121 gtaagtttcc atcaataaca attaaactcc aatcattttc tttggcaagc ttatttgcta
     3181 aagctgtttt tcctattcca ctttcaccta ctattaaagg tacttctcca gtggataata
     3241 ttaagtcaac gctttttaat gtgtctataa aattcatttt tctctctcct acataatctt
     3301 taatttctca tctacagcta ttttttttgc tgtcttactt ccatatttat aaataaacat
     3361 aattttatct attggtatac tttcgctatt tctatctata acactacaat tcaaaaaatc
     3421 tctaatatac ttttcctcaa catcttcttt ggataatact tcttttaata cactctctaa
     3481 ttcatcttta gatacttttt tcagaatgta cttaatcact aaaatattca cttttaaaaa
     3541 ttccaacatt ttatttttat ctaaatcagt tataaagcta atagctgctt cattattttt
     3601 tatagctata agttctgcat tataactagg tgaatctata tatctcaagg catcataact
     3661 tattctcact gcctcctctt gtacactttc ataaggttgt tttataaact ttatcgaatc
     3721 ataatttttt cttactgcta acagttgtaa ttcttcactt ggatttttag catatttaat
     3781 tgcccatcct gcttgattta tagccatttc aataacttta tcagttgggt ttttgatata
     3841 atccagtata ctccatccct catttactgc ttttatcatc atatcttctg ttggattatc
     3901 tataaattta attgctctaa tattattatc tattgctagt tcttgcatct ctctggttgg
     3961 attatttata tattctagta caagcccatt ttctttaata gctaacaatt tcatttcatc
     4021 agttggatta tctattgtag ctataatatt gggattattt tttatcattt caataactct
     4081 caatttttcc ataatgtgcc tttctttcta taattatttt tatatctata ttaattataa
     4141 taatctattc ctatttatat aattgtttct tattataatt aatatacttt ttaatcaaat
     4201 ttaaacagaa taattatacc aatatataaa aaaatttcta aaaaacaata aaattaagtt
     4261 ataaacacca atatatttct attatttcaa tacgtataca attagattag aatctaacgc
     4321 tagtaataaa aaattacttt cccaaagtag atataagcct cattttatcg ttcaaataat
     4381 gaaaatatat ttgatttcat gcaaaaagag tgcctaatga actaaaaagt tcattttgag
     4441 acactcattt ttttatataa gtttatatag tttttaatcg ttcgcattca accactcagt
     4501 taagactttt atatatttct cattttcttc aacgaatggc atatgtcttg aatactcaaa
     4561 taattcccac ttactattag gtattctatc atacatagtc tttgcaatat atggtgaaca
     4621 taaatctatt gctccactag ttactagaca aggctctttt atttcatgta atctatctgt
     4681 aaattcatat ccagaaagag ttcctgtagg agaaaattca ttttgtcccc atcctacaat
     4741 atatgcttca gaacctgatt ttttaggtct tctcaggcac tctggagaat cttctgtcac
     4801 ttcacctgca caatacattt ccataaatct ttctaatgca tcattatatt ctttgctaga
     4861 gtaatctcca gtatttactg catcaagtaa tgctttttgg tcaacctcac tcatatatga
     4921 tattcttctt ttttgttctt tctcccaaag ttttgcagaa gaaagagtag atgaaaggat
     4981 gtaagactta ataccttttg gtttatattc aatagcatac caaatagcct gcatacctcc
     5041 ccaagattga cctaacagat gaatttcatc aagtcctaga tgttttctta gttcaataag
     5101 ctcctctatc caagtatctg cattaaatag ctcaggatgc ccttctacaa atgaatttcc
     5161 acaaccaatt tggtcataca ttattacttg tctaccactt tcagctatct tatccaatac
     5221 ctcaaaatag ttgtgtgtag aacctggacc tccatgaagt aatactaatg gcttcttccc
     5281 ttccgtattt tctcctacta tacggtaata cgttttaaaa cctttaaaag gcatatatcc
     5341 ttcagtaatt ttcatgttta tctcctccaa tttgtaatta taaacaataa tcaagttcat
     5401 taacaatact atttaaaacc tcttatacat atttgattat gtattttaat ctttatacct
     5461 acttttataa atagtataac ataaaagtta aaaatctcta tactaaacca attataaaat
     5521 tatattaact atataatttt attttttaat aatagtatat acatatttga ttattttcat
     5581 ttgctattta aaatcaattt taagttttct tcttataata aacttcctct ttgtggtctc
     5641 atgttagtct ctaaatttaa aattttacaa aaaattttca taaaataaaa ttatattgat
     5701 tgtatctaaa caaatagggc aataaaataa ttaagtatag ttacttacct ttcaagcaat
     5761 attagtttta tgttagaatt ttattatatt gatttacagg aggtttgcat ttgaataata
     5821 ttaattcact taaagtaata aaattatctc ttggatgttc tcttgctata tttattgctt
     5881 ggctattaaa attagaatat tcaatggttg ctggagttat agtactactt acagtaaagg
     5941 acactaaaag agaaactctt aaaggctcca ttggaaagat ttatggtttt cttttatgta
     6001 ctattttttc atatttatgt tttaatattt taggatataa tttgacttca ttttcaatat
     6061 ttatatttat aattatacca ctttgttttt tgttaaatat tcaagatgtt attgctatgt
     6121 gtgtagtcat agcatcccat tactaccttc aaggagaaac ttctatcaaa tggattttaa
     6181 atgaagctgg aatatttgca gtaggaactg gaataggtgt cttaataaat atgtatattc
     6241 caacaaatat acataaaatc catgaagttc aaaaaaagtt acaggaagaa gtgagtattg
     6301 tacttataga cattgcagat attattgtaa atcctaaaaa agaaaatgga tatagtagag
     6361 atttatatac attaaattca cttattgaca gcagtatttc tgaaacttac gataatatta
     6421 ataatacttt attaagtgat actagattct tcttagaaca tatggatatt ataaaaagcc
     6481 aacgggatat cttagaaaat ttgtatagtt atgtatctca actaaattct acaccaccac
     6541 aagctcatat tctatctgct tttatacata agataggtta tactgaattt gaagctgaaa
     6601 caggcaatct tcttcttgaa gaattaaaga gactaatgct tagtatgaaa aaccagcctc
     6661 tgcctgttga cagaacagag tttgaaaata gagctatttt attcctatgc ttgactgagt
     6721 taaaacagtt tttagttaat cgtaaacatg ctcagatgct tagagataat aatttttata
     6781 aataaaaagg ggagaaatct agcagttgac ctgactacaa aatatcagat ataatattaa
     6841 atgcgcccct agtaagaggg cgcaatgttt ataacttatt ctactgtcat gattaaatca
     6901 ttattcatat cgaacataca ttatttgacc aagtccaata ttagcttttt catcagtgat
     6961 ttctatttta atagtcacat catttttttt acagtacttc gctaattctg caccagaacg
     7021 atttttacca ctaaaatcta aagaaaatgg cttatcatat ttaaaaggat attcaacagg
     7081 tttaccctct ggtgctaatg caaacatccc atatggtgtg ttcataaatc ctattacagc
     7141 aatcgtaaga tttgatgggt ctaaatttga ttcactacct gtaaatgtaa ttgtatttac
     7201 tgatgaatta actacactac atctaacacc ttcatacatt acatgttttt catttatatc
     7261 ttctcctttt tttccaaaat ttccaacagc ctttgcccct tcttgatgtg gtaacatagt
     7321 gtgctttcca ggtggtgctg gtttctgtgt ctgttctggt tttaccgtct gtactattgc
     7381 accaactttt ggatatgctg tcttatcaaa tggtaatggg tggctaagac tcttgtatat
     7441 gatatccttt cctgctgatt tattagcatc aatatctaca tgatacaaac gcccatcacc
     7501 aaaacggata agattccact ggtggtcatt tgatgtgctg tgtacataat aagattcaat
     7561 tcccatagca tcacacaaag ctttcatgct cctagccatt cctgagcatg cacctttttt
     7621 agtaaccaat gtataggcag tatttgctcc ctctactgca ttccagtcaa catatgttgt
     7681 gttattttta atgtgattgt aggcaactaa aatcttagca tctgtggtca tattctttgt
     7741 gattttcttg ttcataaaat ctgctgttgc ttgtgctact gagtttagtt gggcttgtga
     7801 cagctttgga ccatatacgc tattggttcc agtgacatag ctttttggtg tttttgctgt
     7861 tacctctttg gctgtcatac cataaactgt catactcata cctgagatta aaactattgt
     7921 tgtaatcaat aacttggtag ttaacttcct aattttcttc atacttaata ttctccttta
     7981 taaaacattg ttacttccta ttctctacca ttaataaaat taatttagta tttaaaaagg
     8041 tggattgtca acatgtatat ttctccattc atacattcgt gaaatattta aattttatgg
     8101 aaaatctaat agatattttc tagataattt gtatacaata caactcgcaa atcagggtat
     8161 ttgctgttag tttgagaaaa tgatgatgat taatacattc ggaatctttg acctataata
     8221 aataccattg tcttcaatca ttaataatgg taagagtaaa gagaattatc aataatacag
     8281 ttaaaatcaa ctttgtatac atttcataca ttctctccca acaacattat acttcttata
     8341 atttgtatat tcaatacgtt ttctgggaaa atataggata tatctataaa aatataaaaa
     8401 aggagttgaa cttaaaattt gattaaaaaa aatcaatttt aagacaactc atttgtatta
     8461 taaaaatgct atatattatt attaagtaag tcaatatttt agatatttat ctatttctta
     8521 ttgacttacg cttatagcct aacttatttg tttagttgat atataaccta gttttaagca
     8581 ttattaatat ttaaataatc aagtatcctt tttgtttctt gtagtttctg ttctgcctca
     8641 tttaagtttt cttgaattat agaaatatat attatatcta tcaacgtaag cattgctatt
     8701 cttgaagaaa tagctccttc tctaagtctt ttttctatat ttggtactac tagctttaaa
     8761 tcactaatct tactaagatg attgtcacta tatttagtta tacaaatgac cttacatcct
     8821 tttaattttg cattttctat agactttatt acttcttttg attctccaga gtaagatatt
     8881 gctatagcta tatcttcttt atctacattt gaagatacca taagttgtgt atgactatct
     8941 aaagaggtaa atgcctgttt atttatcctt aaaagtttca tctgtaaatc tagtgcaact
     9001 aaagccgaac cacctactcc aaatatatat acatttttag cctttattat ctgttcaact
     9061 gcttctttta ttatatcttt ttcattcaac aaccttgttt ggttgatagt ctctatgttt
     9121 ttgtttgtaa ttttgtttat aacactatct atattacaat catagttttc atctacatat
     9181 gtgtattcat tttctttgcc catcaaatct ttagctatct caatttttaa atccccaaaa
     9241 cccgaatatc ccatttttct agaaaaccta actatacttg ctgtacttgt ttttgagttt
     9301 gacgccaatt ctgatacaga aagcttactt atagcctctg tattattaag tatgtaatca
     9361 gctatttttt tatctacttc cgttaaatct tcatatatct gttttaattt taaaatgcaa
     9421 ctcatactct atcacctcta cctatttact ataatatttc ttcttagcaa gtaaacatgc
     9481 tcctaaatct ggagtcaaca ctggtctcac tataccaaat ctcgttttat tcaaatattt
     9541 tttaagtggc tctaatatta aatctcctga cttaaacact ccacctgaat aagatacctt
     9601 tatctttgta ccttgttcaa aatgatgctc taatcctatt ataagcctac ttaattcata
     9661 agctgcatca tcaaatattt tactagcagt attatcacct tcaataactg cttttaaaca
     9721 tatcgtagca aactttgcta tttctattct atctccttgt atttcatcat ttacatattt
     9781 tattatgtca taatcattct ctatattaag atgtcttttt attaaatcat ataattttgt
     9841 ttttgaacac cttccatcag actgcattgt gaacattttt aaggtagcca ttcctatata
     9901 atacgctgaa ccttcatctc ctaatacata gccccatcct ccacatctgt gaagattccc
     9961 atctttatct aaagcctgtg ctattgaacc agtacctgca attatattta tacctttttc
    10021 cccatttaaa gaacctgcta atgctatttc tacatcatta cctagagtat aatttatatg
    10081 actatatgca ttttttgttg ctacttctaa tgcatacaat acttctttta tttttccata
    10141 tccagcaagt ccaacaaatg catacgttat ttcttctaca tttatcttag catctttaca
    10201 aacttcttcc aacccagtta ttaataattt cgttagatta tcaaatccta tttgattata
    10261 atgacaagtt cctttggtta tggttcctac tatatttaat tcttcatcta ctaatgtaaa
    10321 tgttgttttc gttcctccac catctacacc taaaaaatac atactatcct cctacaatat
    10381 ctttaataat tctttcaata cttaatatct aaaaataacc ttccaatgct gtttttttaa
    10441 tattgaaagg ttatcagtac tattatttat tttacaattt ttctattgat tttaaagctt
    10501 cacttatata accttcttgt ctatctagga tactctttgc actatcctta tctaaaccac
    10561 tttttatcat aaatatagcc aatttaacgc tattatctgc ttcttctaag aatttttctg
    10621 caacatcata ttttacattt gtagctatca ttattattct ttttgctctt tcaaccaact
    10681 tttcatttga tgtcttaaca tctaccatca agtttgagta tacttttccc atcttaacca
    10741 tagaagctgt tgttaacata ttacatacca ttttttgagc tgtaccactt ttcattctag
    10801 ttgaacccat tattacttct gcccctacta taatgtttat tggtaaatcc gcttttttac
    10861 tcatttcact attcggattc atagttattg atagtactgc acaccccaat tccttagcat
    10921 actccattgc acctataaca taaggagtcc ttcctgatgc agctatacca catataacat
    10981 ccttagatgt aactcctcta tctattatat cttgctttcc aagttcttta tcatcttcag
    11041 caccttctat tgctttaaat attgcttgat ttccaccagc tattatagct tgaacaagct
    11101 caaaatccac tccgtaagtt ggaggacatt ctgtggcatc tagtattcct atcctaccac
    11161 tggtgcctgc tcctatatag aataatctac ctccctgctt cattctatct actattatat
    11221 taacagcttt tgctatactc tccttttgtt cttcaacagc ataggctaca gttttatctt
    11281 cgttatttat taattctatt atgcctaatg tatcttcttt atctatttgc aatgtattct
    11341 tatttctacc ttctgtaact aaattttcta aagtttttat taacatatca tttcctcatt
    11401 ttcttaatat taaattttta aacacatttt aattccaact ttcataatta tatttttata
    11461 ataaattaat attttcataa taaattattt tgttgagggt ttaaaattaa acttttgcca
    11521 tggtttaata taatctaata taaataattc ttcttttctt atatatccta ctacattcga
    11581 tttaccactg tttttcatat cagtcaaggc tatttgtaac tcccctgcat aatgaccata
    11641 ttcactactt tcaattacta tatctcctct ttttattatt ttaggagtat taaatagttc
    11701 aaatttgtat cctttatatt taacacgaga ttgagtagac cttatcagac tgtcagatat
    11761 gtcccctcta ttaaaatgta tttcttcaaa gagtatcttc ttctcaactt ctcgtatatt
    11821 ttcctctatt gctacatcaa atgtaaccat atcttttctc atagaaccta atacctttag
    11881 ctcctcatat gttggataac aatttgatat tattatatca tttatattat tcatagctat
    11941 tatatgcttt acttgaatat ctataggtag atttctgtgc atctcaattg ttggaagccc
    12001 atcagttaca ggccatggtc caaatgtagt ttcattttga cttgttacaa aaactgctgt
    12061 tcttaatcca tacttattaa atctttctgt acattttata aagtgttcta aatttaatcc
    12121 actatatcta tgtggataaa agttatgaca tcctgtcaag ttttctttat ttggttggta
    12181 gtccattatt gtatctatat aattagtatt attactcata ttgatttcta ttttaagatt
    12241 ttgaggatta aaagtcatta atgcctcttc agaacctgta aatcctatat caagccttat
    12301 tccgtctgcc ttcgtctttt taaaaaaagt caaatctttg tagcttattt ctaattcacc
    12361 aaatactctg ggatttacat caagtattac ctcaaaacct ttaaacttag cgtattcatt
    12421 tatacgttta aattttttaa ttatattttc tttagtatct ttaactgata ataaacatga
    12481 aaatatacgt gtaaatccat tttcagcagc tttatctata taatcatata tttccttaga
    12541 tgttgttttt tctggataaa ttgatattcc taatcttccc atctgtgtca tctccttata
    12601 tcctatatgt gtttaaattt atttcgaatt acacgaaact tttttaaaaa tttggtgaaa
    12661 aaaagtttca tatatattta taaaaaaaga aaagtttacc ttttcttttt ttataaacaa
    12721 tcaacaaaat atcttcgtta cttatttcat aactgttata ctttgaaatt tatactaatc
    12781 taatatagtt tttaatttcc aatatagttt ctaattaata agcttcttgc tcttcaactt
    12841 tttcttcatg aagcaatctc ttatcgtaca tcttgacaaa tggatagtaa attattattg
    12901 atatagctat acataataag ttaagaactg aagctctcca atctccacca gtggctaaat
    12961 atgcccctac tggtcctggt aatgtccaag gagcagtaac tactactctg gatactaaat
    13021 tagcactcat agcaaaccat gaaactgttg ccattactat tggtgctaca acaaatggta
    13081 ttattaatat tgggtttaat actattggtg ctccaaatat tattggttca tttatattga
    13141 atattgctgg tattacagtt gcttttccta aagactttcc ataagctgat tttgctctaa
    13201 atgcaagaag taaagctaag cctattgtag ctccagaacc tccaatccat ataaaccatt
    13261 gaaaaaaggg ttcagcagca atacctggaa ctgcttgacc cgcagcatat gaagctgtat
    13321 tagcatctaa taattgtatc cataaaggtc ttgccaatga acctattatt gatacaccat
    13381 gtattccaaa tgaccaaaaa aacgttatta aaaatattag tataattact gatggtaatg
    13441 tgtcagtggc tgaaactaat ggagttacta atttagctat gaagccatgc caatcaaacc
    13501 ctaggaaata agtaacaata gccattaaaa ttattattaa tgcggctggt gtcagagctt
    13561 caaaagacct tgtgactgat gctggaactg cttctggcat ggttatcttg aatttagatt
    13621 tgtcagtaaa tctataaatc tcaacaccta ttatagatgt tacaatagca acaaacattg
    13681 aacctccacc aagattagcc attggcattt gccatccttg aggaattgaa ttataccaag
    13741 ctaaaagttc tggactcttt tcaactatct ttaataactc aggggtaaga ccctctattg
    13801 cagtaggaac tattgtcaaa aggaatgtag ctgtagctaa taaacctcct gtcaatccat
    13861 ctaacttata tgactttgcc aaactataac ctatgccaaa tgtagaatat actgatataa
    13921 taaaaaatgt cattctatat ggtagtaata ttgtaactgc attttccttt agatactgag
    13981 ttacccccca tgaatctggt aatggaggaa atgctaatat caagaaaaat gacccaacta
    14041 ttataagtgg taatgaagct acgattccat ctcttacagc tcttaagtga cgttgttctg
    14101 ccaatctggc catagaagtt gataatttag tgtctaaaaa ttctgtaaat ttatctagca
    14161 tcttttctct ccttaattaa tatttatttt tattatcatt aaaattttta taaaatcaac
    14221 tttcttctaa tctaacaaca ctgcaactac tatttactca acagttcttg aacttgtttt
    14281 aataactttg gtcctcctaa tggactataa gcttgtgctt gtattaatgc acatggtaca
    14341 ctaacctcat cagcaaaagc ttttaaatag tcaaatctat gtctgacttg tggagctacc
    14401 atagcaatat cccatccatt tttaacttca ttctcaaact cttgagtacc aacagccaaa
    14461 acatctatat ctattccatt ttttgctcct tctttttgta atgcattaac tgctatagca
    14521 cttgacatcc ctgatgaaca aacaaataat actctcatat tgattccccc tgttttttta
    14581 tttcttttca atcattatag catgtatttt tgattacagg aatacgtttg tatatatttt
    14641 ttcatatttt acattttaaa ttgtaatttt atttcatgca tttatatctt gctttaattg
    14701 ctttatttat ctaatcattc ttttgtctaa aattacacac tacttaaaat actcatatct
    14761 tttcttaaaa aagaaaaaag actatcttat tattaacata aaatagtctc aatacttttt
    14821 taaatatgta ttcctttata tatccagaag taacctatta ttgcaaatga taaagcaaat
    14881 aaaatataca gtctaaaaaa tcccaaagaa aaacctctct tagtttcaac aaagtatctt
    14941 gtatatgcaa ctgcaaaaga tgtaattaat gaatttccta taacaactcc aaatctatta
    15001 tctattccaa atatagataa taacaaagga aaaactacag tacttacaag agatgaaact
    15061 attagtatta atccactttt aaaacttata gttggaatat tataatctgt tctttgattt
    15121 ttctccattt gtttcttagt atttttatta ctttttgtac tttttgcatt tttataatta
    15181 ttatttttct ttcttttctt ttttttatta ttagacatgt catttacctc caaaaggttt
    15241 aggtgttata ttccctaaaa taactttatt tttagcccct gttgcagata ttacattaga
    15301 aaaagaatta tttaatgttt cattgcccaa gattacaaat gccaaagcct cctttgcatc
    15361 agaagaatac ccatattcat cttgagttaa tacttcaacc tctaataata actcttttat
    15421 atatcctatt aaagttagat tatgagctcc tccacctcca attaataaag tatctacatt
    15481 aacctttgga agtatgaagt ttttataatt ataatatata gcttttgccg taaacatagt
    15541 tactgttgct atcaaatcat atttatctac atgtttatat ttgttaagca tgttatccaa
    15601 ataaacttgt ccaaatacct ctcttccagt gcttttaggt ggcgcttgac taagatactt
    15661 atgactcatc aaatctttta acatttcttc attaatttta ccttttgatg caaagtatcc
    15721 atttttatca tactttctat taaataatct ttgacatact ccatctatta tcatatttcc
    15781 tggtcctgta tcaaatgcaa atacatcatc tatgttacat gatttaggta ttatagtaat
    15841 atttcctatt ccaccaatat tttgaagtgc taaattttta ttgttatcac tatataataa
    15901 aaattcacta tatggtacta atggagcacc ttctccacct gctgctatat ccattactct
    15961 aaaattagat attacctttg tatttgtttc atatgctata actgctggtt cacctatttg
    16021 aagcgttgaa gatacaaaat tattataact tcttggtata tgaaagattg tttgaccatg
    16081 agatgcgata aaatccaaat ttgctatatg aaagtttgct ttatgacaca ctgattttac
    16141 agctttacta aataaatatc caagcttaaa atttaagcta cagattaaat caacactcga
    16201 ttcctcttct atacagcact ttcttatttc gtcttttata tctttaggaa tttctagagt
    16261 tataaattct atttgcttaa ctttagtatt tctaccattc ccactaattt cagctagtac
    16321 tgcatcaact ccatctaagg aagttcctga cattaaacct acactataca tagttatcat
    16381 ccttttaagt ttatagttat tcctccccaa atcaaggtat taagtttaat aattttagaa
    16441 ttaatcttat ttcatcttta attacgataa tttactctta tgaaattaat tgagttaatc
    16501 ttatacacgt tttttacctt agctaaatct tacattaatt tattttcagt gtcaatgtaa
    16561 taccatgtaa ttttttttca caaacaaaac atattctctc tccaaaaacc atattaaaat
    16621 agttactaca aataaaaaac ataccaggta catatctgat atgtttttca tatataataa
    16681 ttattatttt ataatataga tagagcatca tttaaggcac taattaaatc ttcactattt
    16741 tcaagaacta aatttattct tattgtatat gtcgatttgt atatgatgat agattttata
    16801 gtctaataac ctaactatct aggcttaaat aatctgatat atcataaaaa tagatattaa
    16861 aaattgtata tgaaccattt tccgaacata cctcaatctc atgccctaaa ctatctatca
    16921 ttttctttac aaaatacatc cccattccag tagacttata caattgattt cttccatttt
    16981 tccccgtaaa tcccttgtca aaaaccctag atatatcttc ctcatttata cctataccaa
    17041 aatcttttat agataatacc actccatttt ctaacttttt tgaattaaat tcaatcttac
    17101 caacttcctt tgaatacttt atagcattat taataatttg gtctaaaaca tatgacatgc
    17161 atttagaatc tgtgtaaaca tcattttcta attcattcaa actaacttct acattatttt
    17221 ttataagcaa aaatgaatta ttttttatag acatttttat caatttttct aaattaaatt
    17281 tatttataaa tacatcttca aacatagtgt tgtttctact actatacaaa atagagttta
    17341 ctaaaaaatt tatctttgca acctgattct taatatccaa actatcttct atgctactta
    17401 acctatctgt aattatactt aaagaagata ttggaatttt tatttcatga acccatttag
    17461 ctatgtactc atccaattct tttaatgatt gtttataagt ctctatgtca ctattatttt
    17521 ttatttttaa gttttctata atatctttta ttagattttc ttcaaaagat tgtccatcaa
    17581 ctaaataact gtctatttca ccactatttt ctatacaatt atataaattt gtgtaactat
    17641 ttctaaaatt tatataatct ataacaaaaa ataccattat tataaacagc actaaaaaat
    17701 ctaaatatat taactctgaa tatttatttt taaaaatatc tatagcaaat aagtagatat
    17761 ttattatact aactacaact aaaggtagag caatatactt agacctacct tttaaatatt
    17821 ttactagcat tgtattatat atcctatccc cttcttagtt tttataaaat catcaaaacc
    17881 tagttcttta actttacttc tcaatctatt catatttaca gtaagtgcat tgtctgtcac
    17941 aaactcatca ttatcccata gagtcatcat aagactttcc cttgatacaa ccctattctt
    18001 attttttaat aataatgtta aaatttttat ttcgttttta gtcaattcta tacttttatc
    18061 cttatactta tgttttataa tccctttccc cacatcaaac atcaaatctt cacaatacaa
    18121 aatactatta gaatcactat aattatagac tcttcttatt ataccattta ttttggtaac
    18181 caatatttct atagaaaatg gtttggtaat gtaatcatct gctccattat ttatacccat
    18241 tattaaatcc atatcagaat ctcttgatga taaaaatatt aatggtacat ttgaaatagc
    18301 tcttattttt tcgcaccagt aaaatccatt atataatggt aaatttacat ctaaaagtac
    18361 tacatctggt tttctatcta taaattcatc taatactacc tcaaaatcat caattaatcc
    18421 tactttaaat ccccattttt caagtgctaa tgcaatctct tttgataaat caatatcgtc
    18481 ctctactaat aaaattctat acatttgtat attctccatt atcctaatat ttcactatgc
    18541 tatgaattat taatatcata acatatttta tatgaattta ttacccaaat tatttagtta
    18601 atcaacaagg agactcttat tacaagaatc tcctttctct ttattaatat atcaactaat
    18661 ttttatacac tacactctta aacttattaa cagatactgc tccatatatt atgaatatta
    18721 tcaaacatat cactaaactt agtatatata taccaaataa atcggtcatc aataaatctc
    18781 ctgctaatct caatgcaaaa taactagata tagttgcact taacattggc aaagtataaa
    18841 aaatagctac ttctttaagt atagctctat ttatatcttt ttctgtagta cctattttta
    18901 acaaaatctt atatttctct ttatcttcat atgcatcact atatattttc atatatatta
    18961 tacttccagc tacaattgca aagactaaga ataaaaacac aagcactaca tatgcaaact
    19021 tcatccattg actctcacct tgagctttat atccattttg aatatacaca ttttttaaac
    19081 ttaaattctt ttcaatattg ttgaacatta cttgactatt ttcttcttga aatacctttg
    19141 caccataaaa atacacttgt tgacccttat ctcttagttt aaaatatgta tcatcattta
    19201 ccactataat actttgatta agtcctgtcc ctagtactgg aacttttact tctccccttg
    19261 aaatattata taactgacca tcaagtttta tcttggcttc ttttgtagct attgatgcta
    19321 tcgtttgagg gctttttaac tctattacat tatttccact aactaatctt tcaccatact
    19381 cttttaattc tttatcattg ccattcactt taagagtatt acaaaaatca ctatatttca
    19441 ttatagtatc tgttgtatca taagcttctt ttatatctgt tttctttaaa attgttagtt
    19501 ctggatttac tgagtacttt atcttattag tatcttttat tatattctct atttgttttt
    19561 tattcacttc atctttatcc attgaaacta tgctaatagt gtacacattt ctttgttctt
    19621 gggcattctt atgtatacgc ttcatcgcaa ctgaagcacc aagagttgat attgttgtag
    19681 ttataattat agctattata gcataagttt tatagttttt atttaatcgg tagtttatat
    19741 tgtttattgc aattatatta tttccattaa ataatatttt tttatttttg attataatat
    19801 caaatataac aggcataact gatttgaata atccataagt acctactatt attataccta
    19861 taacaggtag tacactagtt atatctccag ttcttatatt ggtagaaaga tagtagccat
    19921 atcctattac tataattgat actatagcta atatatatat acctattcct acctttggta
    19981 ttttttcttg ttttttagat atattgatta gatttattac actacttcta catattgtta
    20041 taaaaccttt tacagccatt attataaata tagaaataaa gattaaagta gcatatagta
    20101 tagcttctat actaagtcca ttagatacct ttatattaaa tccagataac tttattatca
    20161 ctacttgaaa aaatctagat gttattatcc ctataattat tcctgttata caagaactta
    20221 ttcctataag catattttct acaaaatata tttttcctat agtatataaa tctaatccca
    20281 taaaagacaa tattccaatt tctttagacc tattcttaaa aaatatattt gttgcatacc
    20341 atataaagaa aaataaaaat actgatagta tcattattac agctactaac actgatagtg
    20401 taaatttttt attttcatct tgtaacacat ttatagcatc accatatctt aataattcaa
    20461 aattagttag cacaactact gaaaaaacca tagatataaa aaatgctaga taagttctta
    20521 tgttactctt aaaattatta taagcaattc caagtatact cacttacatc tcacctccca
    20581 tagaggctag catatccata atttttccat aaaattcttt tctactattt cctttgttta
    20641 atttacactt tatatttcca tcatttatca tatatacttc atttgaataa cttgctgtta
    20701 gagggtcatg tgtaatcatt ataatagtag cgttattttc tctgtttatt ttttctaatg
    20761 attctaaaag ttcatatgct gatttagagt ctaaagcacc agttggctca tcagcaaata
    20821 tgactgttgg atttgtaatt aatgacctag ctgctgcgcc tctttgtttt tgtcctcctg
    20881 ataactgata tggatattta tctaaatgat tttctaatcc aaatttttta gctatagaaa
    20941 ataccttagc ttctatctcc ttacttttct tttttcctaa tgctagagga agtgctatat
    21001 tgtccattag tttcatattg tctaatagat tatagtcttg aaatataaac cctatttttt
    21061 ctcttcttaa ttttgatagt tcattatttt ttacttttga tatattaatt ccatctagta
    21121 ttatttctcc tgaagtttgt ttgtcaagtg tagacattaa atttagcaat gttgtctttc
    21181 ctgcaccaga tggacccatt attgatataa aatcaccttc attgactgta agagatatat
    21241 tttttaatac atttgtttta aatcctttta ttccataatc ttttgatata ttttttattt
    21301 ttaatatttc tttcataata atagcctcca gttgctaatt ttttaatata tatttatttt
    21361 aaaggtttta tataaataaa tccttaagta aatattacat tttaactgtt agcattacac
    21421 ttttgtaaca tatggaagac tattataatt ataatggaaa tatcttaaaa taaaagcatg
    21481 atttacttct ttgtataaac aaagaaaaga agctcctaag aagcctctaa tctatacaat
    21541 tattcttctc tataaaaaac caaaatacac attgattgtg gcaaatacag atactataaa
    21601 caagtgatat tactactata tattaaaaca attattcctg aagataattc aataagacta
    21661 tcaagcaata agctaagcat ccaaaaagac ttaataccat taatgtataa ttatacccaa
    21721 tattaatgct caaaaaacca gcaacagttg gaataatcag agatgaacct cccataaata
    21781 tacttaaagc tattaattgg ctactacttc taagtttttt aggagaaact tcaaatatta
    21841 atctttttga agtaattaaa attaaaggag tagaaaacac ttgaaaaaca cacagtataa
    21901 taatgatatt tgaatcattt gttaaagcaa ataatagaaa ctgaactgtt atcataatag
    21961 cacttaattt taataagttt aaactgctat atttttttaa taaataagaa ccagccagat
    22021 atgttggtat ctctaacaat gactgtaaag accactttaa agatatctga gaatttgtag
    22081 catttaaagc tatcatttta tctattacag tacagttatt tgctaccacc attgagtata
    22141 ataagaataa aatacatact agtaagatat attttttatc ttttaataat tcaataatat
    22201 ctttattagt tacatttatt ttcttattaa tcttttcaat atcaggtaat aatagtatat
    22261 ttataataag taatactaca attaaaccaa tcgctacaga taatccaaaa tatgagaatc
    22321 taagaatcaa gtaagatgct accatacttc caatagccca tccaatcgac ccaaaagtct
    22381 taataaatga caaataatta ttaatattat ctccacaacc tattatccat gtatcatata
    22441 aactacagca agtatttaat aatcctcctg ataaagcaac aagtaataag tatattataa
    22501 aagttgcaga ttcagtagaa aacataataa ctgatgcaat tccataaact gataaactaa
    22561 ttaaaacaat ttttttcatt gtttgatact tatcagctaa tactccaaat aataattgaa
    22621 acaatatatt ggttattgca tagctcgata atataattcc tctttcaaac gctgagtaac
    22681 ctaattttga taagaaaggt gtgaattttg ttgaagcaaa ggcaaaaata atatatgaga
    22741 aaaaatagaa tattataaat ttaaatttaa tcgctttatt aatcataatc aatcaaaatt
    22801 gataacttta ataccactat ttccttcctg atttaagttt gaaagatgat attttaccgt
    22861 attaggattc tctacaataa ctaaaggaat atataaagta ttttcaagta acttattatc
    22921 aatttctact aacttttccc ccatattaac ttcttgacct tgtttaactt ctaatttaaa
    22981 gttttctttt tttgttgttg cactatccaa tccaatatga ataagaattt gaacatcatt
    23041 ttgcaattta attcctatag catggttagt ttgagcaata aaacttatta ctcctttagt
    23101 cggtgattta agaatattgt cctttgctat catagcaaat ccatctccca ttaccttagt
    23161 tgaaaatact ttatcaggaa tttctccaag attaattatt tttccatcaa tgtatgaatt
    23221 aattgtaatt gcttcttttt ttcttttaaa gaacattata gacactcctc tacataatta
    23281 actttattct aattatcatt acaaataacg atattaagca tactgcaatt gaggaaaaaa
    23341 gagccttata gctctttccc cattgtagtt ctttaatact gcttatgatt tgtttaattc
    23401 caacaaattt ataaatatag gtaaacatga taacaatagt tattgtgtaa atttggaata
    23461 tctgccctaa taagactaaa tagaaagcaa tcatgttttc ttttatctct ttattctttt
    23521 ttatattgta aataacatat gcactgtata ctgcactaaa gttagagatt aaatttaaac
    23581 ttgcattaac atcattgttt aaaagttgtg aaaatgaaat atttgtaaat gatgatgtca
    23641 attctaaata cactatatat aaaacaggta atattagaaa acaaaccata accactgaaa
    23701 gaaatatatt ttcatctttt aatactgctg tgatattttt tattttattt gttatcatgt
    23761 ttttgttctc cttatttaaa agttggccag aaatccttat tagccacaat catttcatct
    23821 aagatttctt ttgctacttt tgcacttgga acagttttac tcatagtaaa cgactgccat
    23881 aatttttgat aacttttttc tatccatgct tctacagcta atttttcaga agcaacttgt
    23941 tgttccatta aacctttttg gaaagttgga attttaccta tagacatagg ttcaaccata
    24001 tcttttccaa caaggcaagg aatttcaacc attgcatcat ctgcaaaatt ttcaatagct
    24061 ccattattag gaacaatcag taaaaatctt tcctgagtat taaatgctaa tgcacaagct
    24121 aattcaacaa taaattgaga atgttcactt gcatcaaacc atgtatctct tgctgtgcca
    24181 ttttttataa ttctttcaca ttcttcgaat gtatcctttt ctcttctatc cataatttca
    24241 tttgctcttg tataatttgg attagcatgt tcaacagttt catcagccat taaataatat
    24301 tttaaataag tattaggtaa tgtagttggt tctatttcca ataaatcctt tgctgctctc
    24361 atagtttcta accaactaga ttctttgtgt tgaccttgag gtgtaaattc ctcatatcct
    24421 tttttagcac aatattcctg taatttaggc attaaatcat ttccttcttt gtccttaata
    24481 cttgtccacc acccgaaatg attcaatcca taatatctaa catcaaagtc tttacgagaa
    24541 tttaaaccta aaactctagc aaatatttcc tctaaacata ctggcatatc acaaatatta
    24601 ataattcttg aatttggtct taatacacga catgcttctg caactatagc tgctggattt
    24661 gaataattaa gcatccaagc atttggagaa tatttttcca tataatcaat catttcgatt
    24721 attggaccta ttgttcttaa tccataggca attccacctg ccccacaagt ttcttgacca
    24781 acaaccccat attttagtgg aattttttca tcttgttcac gtaaagcata taaaccaaca
    24841 cgaatttgtg ccattacaaa atcaatatca gtaaatgctt cttctggatt tgttgtataa
    24901 ctaaatttaa tttctggatt tttctctcta acaattattg cacatgcttc agcaactttt
    24961 ctttgtctat catcattatt atcatataat ttaattgatt caataggaaa tttagcaaca
    25021 ctttcaatta acattgttac aattccagca gtataagtac tacccccacc agcaattagt
    25081 atcctctgtc tttttctttc catctttcct tctcctttat aataaatttt caaattcttc
    25141 tcttacactt ggtactgaaa gcccaataat aatctgaata gcttttccat tatgcactaa
    25201 accatgtgca cctactgcct taaaatcttc ttctttagaa ataattgagt catctttcaa
    25261 ggttaatctc aacctcgtag cacagtttgt aacatctaca acattttctg ctccaccaac
    25321 taattttatg tattcagatg cttgttgaga ggctttactc aatttatttc ctttttcatc
    25381 tttagtttct aagtattcat ttttagtata tagttttgtt tcttcactat cttcctctct
    25441 accaggagtt ttcatatcaa acttcttaat taagaaagta aatacaaaga accagataaa
    25501 tgaaaatata atccctacaa caacttgaac aacatatacc ttccagtgat acattccaag
    25561 aggaagccaa tttaatacaa cccagttaat aattcctcca ccaaaatcac caacaactcc
    25621 tagggcaaac gaaatcgttt gcaagcatgc atctaaaaat gcatgtacta ggaataaaag
    25681 tggtgctaca aataaaaatg taaattctaa cggctcagta attccagtta atactgcagt
    25741 aagagtagca ggaatcatta aacctaatac ttttttcttt ttttctggct ttgcagttac
    25801 atagaaagca ccaaatacac ctaatgaacc aaacaccttc gataatccgg ataatgaaaa
    25861 tccgattgga tacatttcct ttagagtctt agctgaagtt tgaaaatcct gaatatgagt
    25921 agcccaatat actgatgtac cacctggaac aacaacacta tcataacaaa ttggtgcata
    25981 tacaaaatga tgtaatccag ttggtattaa aatcttttgt aagaatgcat aacaccaaac
    26041 tcctatattt ccactattta taaaaaacgt ttgcaaatgt ctaataacat tttgaatatg
    26101 aggccaaata aaacaagtta ataatgcaac tggtatcata acaaagaaac aaattgcaac
    26161 tacaagtgat gagcctctaa ataatccaat aaaatctggc agttctttat cataaaatct
    26221 attatgaata taaatgacaa tacctgatat taacaaagca ccaaccatac cagtatctaa
    26281 tgttttaata ccagcaatgc ttacaagtcc acttccagca cttatttcag ctgcgaaatc
    26341 aactccaaag ctttttcccc aaaaacttaa catagaacct acaaaataat taaaagtcaa
    26401 atacgttgct aaagcctcca tacaagctct tgcttgttgc ttttttgcaa gtgctattgg
    26461 taaagaaata gcaaataata atggcaattg attaaatacc atccaagctc cactagatat
    26521 tacaccccaa aattggtacc aaatattttc tggtgtagca agtgaaccca taattgactg
    26581 attttgaaat acaattgaga atccaaccat tatcccagca aaagcaaata atagtgttgg
    26641 tgtaaacatt gcccctccaa aacgctgtat tttcttcatc atataaatta ctcccctcct
    26701 catattttta gtttatcttt ggccttagat atctattatt ttaacaggtt aataaatata
    26761 tacaatcttt agggtacatt cggagcttat tcacagtcaa ataagttttt gcacattttt
    26821 atgttcaaat tctcataaaa aaaaagaatg actacaattt gcaatcaatc ccttctgtaa
    26881 tcattctatg ccttttataa atactatatt taataaataa taactcaatc aatataaaat
    26941 ataacattgt caatttataa ctagggtgca tttgtaaaaa tgagatatta gtcgctgaaa
    27001 tataaattga ttcatcactt aaatcagtca atgtattatt tttaaactct gtaattgaaa
    27061 ttattttagt tcctattaat tttaatcttc tagcaatatt aagtgtattc tcattctcac
    27121 cacttaggga tataataatc ataacatcat ttttactgac aatattgtaa aaagaatcat
    27181 caaatgttct tccctcaaaa tcatatatta tttcttgaca tgataagaac attctcttta
    27241 tctgttttgc aactacattt tgaatatcac ctgaaccata agcgtatatt gttcttgatt
    27301 cataaagaag tttacacaat gcatcataat ctttattttt ttgatcttca acatacttaa
    27361 ttattgaatt acatgcaata tcaaatgact gattttctat gacatgaacc ttttctgatt
    27421 cccagcttaa taatacttta aactcactga aaccttttaa atctaatttt ttaacaaatc
    27481 ttgtaatagt tgcacgagac acattacatt tcatagcaag ttcatttatt gacatcttac
    27541 tacaatgttt tttatttgca gttatatatt tccatattaa taaatctgta tcattcaatt
    27601 tattataatt taaaaaaatc atttcttcta atctcataaa ctattacccc ctttaattaa
    27661 aaatcgtcat aaatattata ccaatattca acattaaatt acagcgtatt cttatattta
    27721 ctatttagcc cataaaattg actataaaaa atactgctat aattgatgtt taaaaaaatg
    27781 tagttttaat tttattcttt tatctaataa ttaatatttt caagttctag tgcttttctt
    27841 atacaattat catctttaaa atcagcagtc cttttacaat cttttacttt aaattctgga
    27901 atagttttaa attcctcatc acatattcca ttcttattta aatacataca acttgccatt
    27961 ctaactatta gaccactatt ttttaaatta aacaatacag ggtctataca ccctccatct
    28021 ccgccagtag tttcaccaac taaagtcgca aatttagttt ctttacaaaa cattgcaaat
    28081 gactctgatg atgaatatat ttttctatca acaagtaagt atatattacc cttaaatttt
    28141 gaatcatctg tagattttat agtataggaa gtatcttcaa aatcattaaa atcttttata
    28201 atttctttag gtgcattttc ctttacactt gttggtaaat tttctacagg atttaatttt
    28261 atatttcttg catttgtata ttgttttact atttcattat tatttctata aattctataa
    28321 ccatttattt tgacatcatt ttttatgagt ttagatacga ttccctgcca ataactatca
    28381 cttccaccta aattacctct tatatcaata attaaagctt tatgtttttc taaagtgtca
    28441 atataatctc caattatttt taaatcatta tttatagagc cattctttga tgacattgat
    28501 ggtaaataca tatatccaat ctgaccctta ataacatcct ttaaaattaa ttcttttttt
    28561 acaaaaatat catctggcat ttttatttta agattcatag agtcatatct atctacaact
    28621 tttttatcat taagaaaatc ataccaatca ttattagagt atgatttctt aaaaagttca
    28681 tatcttttct tattatctat tacttctgtg tgtttattat ttaaatcaga taatatagat
    28741 gacatttctt ctataaattc ttcatcattt tcagtgtttt ttattcgttt tgtatattca
    28801 tccttatttg ctaaccaatc aatattatta agcctcttat ttacacctag atatggatat
    28861 cctgtcttta caacattata cacataatta aagtcatcca ccttttcctc ttcagacaac
    28921 tgattctttt gagaataagt agaattacct aataagatta taaatgctaa aataattact
    28981 aaaaataata ctttcttttt catgtaattc tcatccactt tcagatttta tattttaata
    29041 cattgtatca ttattttatt atcacctaaa cagttaaaag aaattcttga agatatattc
    29101 cactattatt ctctttaaaa atttttattt gtattttcaa aattatttca tgaaagttat
    29161 aaaataacaa ttatattcaa atatctattt tactgctata tcctgaaggt aaattcttat
    29221 cagtgatata ctaaaaaaga tatgctaaaa aatttatcca ttataatgac ttaaatttag
    29281 atactttact gatttttatt tattagttga gaaagatatt gataattaaa aatattgata
    29341 actatagaaa tgattatttt ttatagaaat tttaaggata taaactaatt atacttaagt
    29401 ctatatcctt aatttatcat gattatgaga atttttacaa atacttatct ttgtccgttt
    29461 tagaataaaa acaagaacat atcctgttat tttattcaaa catccaaatt taattactac
    29521 acaattactt attagaaatt gtatctactt catatatata tctgttaagt atagcttcta
    29581 gcatttcttg tcttccagac ttattcttta taactggcat ttgcagtgca taagattcta
    29641 actctttaaa tccaacctta ccttctacta tatccttacc tataccttca ctaaaacttg
    29701 catatctttc tttagtaaag ttttcaaata cctcatcttc taataattta tgagctatta
    29761 ataatccctt tgcaaatgta tccattcctg caatataagc taggaataag tcttctacct
    29821 caaaagatgc tcttcttact ttagagtcaa agttaaatcc tcctggtgct attccacctt
    29881 gctttaacac ttcatacata gcaagtgttg catcatatat atttgttgga aattggtctg
    29941 tatcccaacc taataatagg tctccttgat ttgcatctat actacctaaa acattgttta
    30001 ttcttgctat atttaattca tgttggaaag tatgtcctgc aagtgttgca tggtttgctt
    30061 ctatattcat tttgaagtat ttatccagat tatactttct taaaaatcct aaaacagtag
    30121 cagtatcaaa atcgtattga tgtttagtag gctcttttgg cttaggctct attaagaatt
    30181 ggccagtgaa tcctatttcc ttagcataat ctacagccat ttgtaagaat cttgcaaagt
    30241 tatccatttc aagttctgta ttagtgttaa gtaaagtttc ataaccttct cttccacccc
    30301 agaatacaaa attttctcct cctaagtact tagttatttc catagctttt ttaacctgag
    30361 ctgctgcata tgcatataca tctgcattac atgttgtaga tgcaccatga acaaatcttg
    30421 gatttccaaa catattggca gttccccata ataactttat acctgtcttt tccatattaa
    30481 cttttatata ctcaactatt tcatctaata tcttatttgt ctcttctaaa tctcttcctt
    30541 ctggtgctat atctctgtca tgaaaacaga aatactcaat tcccatctta gacataaatt
    30601 caaatcctgc atcaacttta atctttgcta tctcaattgg gtctgttata ttattccaag
    30661 gtctctctac tgtgcctact ccaaatgggt cattaccctc tccacataaa gtatgccaat
    30721 agctcattgc aaatcttaag tgttctttca tagtcttatt acctaccact tgttcaggat
    30781 tgtagtatct aaatgctaat tcattgtcag attttactcc ttcaaatttt atctgtccta
    30841 ttcctttaaa tatttcactc atttcatgtc ctcctaatat tttacacata taatatatgt
    30901 agtatgtttt cttaatttaa aactattttc tatctttatt tttcttttta agctaattta
    30961 attatttatt tttgcattaa ctacttcatc taataactta aagtcatctt tcaaagattt
    31021 gtatattctt ttatacaatc tatgatatat attgtatgta tctacatttt cacttattgg
    31081 ttctaattta gttgaagttt ttattatagc atcacatgct ttttgtatat tttcatatat
    31141 tccagctcct actaatgcaa gaattgcaac tccaagtgct ggtccttcac ttgaatttat
    31201 agtatataca tcttgattaa acatatctgc ttgcatctgt ctccatactt tactttttcc
    31261 acctccacct gaggctctta cttcattaac gtctatatta agattctcta ttatatccat
    31321 acagtcttta agactatatg aaacaccttc cattattgac cttgcaattt cttttttaga
    31381 atggattgga gataatccaa agaacacacc tcttgcataa gggtcaagat gaggagttct
    31441 ttctcccatc atatatggta agtaaagcaa tccattacat cctgttggta cttgacttac
    31501 ttgattattt ataatctcat atacatcttc acctaaagaa tttgaaactt ccacttcact
    31561 ttgacagaaa ttatctttaa accattttaa tgacaagcca gctccttgag taactcccat
    31621 aacatgccat gtatttggta ttgcatgaca gaaagtatga actctacctt ctttatcaat
    31681 ttttggctct tttgtataag caaatactac acctgatgta cctatagtag atgaaactac
    31741 tccatcttta actattccat ttcctatagc tcctgctgct tggtctccag ctcctcctac
    31801 cactattgtt ccttctttaa gccctgtcaa acttgctaca tctctagtca cataacctgt
    31861 aatctcttgt gattcataaa ctttacctaa aagattttta tctatattta acttttctag
    31921 tacttcatcg ctccaatctc tttttcttat atcgagcaac tgcataccac ttgcatctga
    31981 tacctctgta gcatattcac ctgtcaattt gtatcttata taatcttttg gaagaagtat
    32041 tttattagta tttttatata tatctggttc attgtttcta acccataata tctttgatgc
    32101 tgtaaatcct gtaagtgctg gattagcagt tatttcaatc agtctttctt cacctactaa
    32161 atcagttatc tcctcacact cttttactgt tcgttggtca caccatatta tagagtttct
    32221 caatgtttta ccttcattgt ccagcataac tagaccatgc atctgtcctg ataatccaat
    32281 tccttttata cattcactgc ttatatttga actttgaact acttctctta tagattcgac
    32341 tacagctttc caccaatcat ttgcatcctg ctctgcccaa cctgatttct cttgtataag
    32401 aggatattca tatgtacaac tttttatagt atttcctagt ttatcaaata aaactgtttt
    32461 agtacctgat gtaccaatat ccacacctaa tacatactcc aacttcatcc ctccttgaat
    32521 gccacttcat aactatcgtt ttcctatcct aattttttta tattttaggt atattttact
    32581 tgctttattt ttgttagtat attaaactaa cttatgaact aataataaaa tatttaatta
    32641 tctttgtcaa tgcaaaataa ccttttattt ttgtgtaaaa agtattacaa tattatttta
    32701 aggaggaata tcaaattggt tactgataaa tacactattc gagaaatgaa tgaaagattg
    32761 gtacttgaac aaattataaa aaatggtcct atttctaggg caagtatagc ttctactata
    32821 ggattgaata aagcaactat atccgctatt accaaaaaac ttattgatga atctctagtt
    32881 catgaaatcg gaattggaaa tagtactcat agtggcggaa gaaaacccat attattagta
    32941 tttaataaat gtgcagggat ttctttaagt atggacattg gatacgacta tatattttct
    33001 tctctatctt acttagatgg aactattata aattctaaga aattaacaga tatacaagta
    33061 agtaaagaca atgttataca attgatagat gaaattataa atagttataa catatccaaa
    33121 atagacactc cttataaggt aattggtctt actttggcta tacatgggat tacttgtgaa
    33181 aataaagtat tgtttactcc atattacaat cttaatgaga ttgacttata tagcatcctt
    33241 agcaaaaagt atgactttcc tattcatata gaaaatgaag caaacttaac agctttagct
    33301 gagaatactt tttcaactgt acataactca ctacttagtc tcagtattca cagtggattt
    33361 ggttcaggca ttataataaa taataaatta tatagtggca gaaatggtat gagtggagaa
    33421 attggtcaca ctatcatcat gcctaacggt aaactatgtc cttgtggaaa tcgtggctgt
    33481 ttagaacagt attgttcaga aaaaaaggta tttgaacagc tttcttcttt agaaaatatt
    33541 cctaaaatag attctgatat agtaaagcaa ctatattatg aagataacca taatgccaaa
    33601 aaagttattc atgagttttg tagttactta acaatagcta taaataatgc tattacaact
    33661 tatgctcctg aaataatata tttaaatagc caaataatta gtgatatacc tgagatatta
    33721 cagattacaa aagatatgtt agttagctct tttaacaaag gaataaatat agaaatttca
    33781 tcattagggt ctgaggcatc tctatatggt ggctctgctg taaatatcaa gagctttttg
    33841 aatatacaaa atttaacttt aattaatgaa atataagggt tatgactata tacagccata
    33901 accctttaaa ttatacattc taaaattaga tttattatat agtttatgca agattagcta
    33961 tattttttaa aaattgtata tcaattaagt attaacataa gtacttcgtt ttaaatatta
    34021 atataatctt cctactcatc atcagataat aaacttgcat tttgttcaac catagaaata
    34081 ttatctttac ctattttctc taattttgct gccaattcct ttgtatctaa aaaagctgat
    34141 tcaataacca tacctaaatt tagccctgaa ataattttaa ttcgactgtc attattggct
    34201 actaataaag cagcattgca tggagttcca cctagtaaat ctgccattat aattatttct
    34261 gaactttcct tgtacacttc taaagctttt tttaattttt ctattgttcc ttctattcca
    34321 tcatcttgtt tcatatttac agtaggataa tctatagaat cccctattat catttttgca
    34381 gaatttaaga cttcttcagc catattgcca tgactcatca aaataatact attcaattta
    34441 atacacctct ttaaatctat aagatgtcta caagataagt tttcttatca tcaggcgtca
    34501 ttatagttgt aatttcaatt ccttcatcta aaagtctttt aaatgcttct ttctcttctt
    34561 cagtaacact gatattaggt cttagaactg ttgtatcttt tctacttgac atatttccta
    34621 catttatatt atgtatttta aatcctgcct ctacaaatgg aataaggtcc acaggagact
    34681 taacaattaa taatacattt tgtccttcat actttcctgc agtaatattt tttatagcag
    34741 tctcttctgt aattatagat gacgctatac ctgcaggtgt agccattctt aaaacttgtt
    34801 tttgaacaga attgttagct actgcatcat ttactaccat taatcttgta acacccaatt
    34861 tattactcca catagttgca acttgaccat ggattaaacg gtcatctata cgaatatttt
    34921 taataccttt catttccata tctaatatca tcctttcctt attttaaaat acctaatgca
    34981 tataaaatta ttgaaacaac cattactcct aaaattaagt atataggttt tatattcttt
    35041 ttaagagccc aataaacaat cacaactaga attgcaggaa ctaacccagg cataatttgg
    35101 tctaatattt cttgaccttt cattgtaaaa tcaccttgtt gaaagttcaa agcaacatta
    35161 gcttttacaa ctgaaggtat taatgcacct acaaccatta aacctaaaat agatgtactc
    35221 tcagttaaaa tctttaaact tttttcaatt gaagatatta gcttagtacc tgatgtataa
    35281 ccagcattaa atagtggtat acttaataat ttcaatgcta cactcactac aatccacagt
    35341 aagattccaa atggacttcc atctatcgcc atattagctg ctatagctcc aaaaattgtc
    35401 cacggaataa cgacaaataa actatctcct aaacctgcta ctggtcccat caagcctgtt
    35461 ttaattgaag caacagcctc ttcagtctct tcacttgata actcctccat tgctacatta
    35521 atacccaaaa tataaggggc aacccaagga ttagtgttaa aaaattgtaa atgatttaat
    35581 acagcacttt gtaacttttc tggattatct ttgtatacta cttttaaaaa aggtagtact
    35641 gcataacagt atgccaaggc ctgcatcttc tcataatttg aagaaacaga actagtaaaa
    35701 aaccagcgcc ataagacact ttttttcacc ttttcatttg atttatttaa tgatacctta
    35761 tcactcatct tcgtccatac ctcctactac agtatattgt tgttcttgat tttccaaatt
    35821 ctttttgtaa attataagtg caattgctcc accaattaaa gctacaccta ataatggtac
    35881 tttcatatat actgctaaaa caaaaccaat tactaagtaa ctaaaatact ccttagcagg
    35941 aagatatcta agtaataatc ctatccctac tgctggaagt agtcctccag ctactgttaa
    36001 accacctgtt aaccattcag gtgtatattt caaaatggta ttaattaaag aaggtccaaa
    36061 tattacagat agagcaactg gaatacctgt tgtagctgct gttaatagta ctcctaacat
    36121 ttgcatatag gttatatttt tataatttcc ttttttagct ccatcttctg ctttatgaac
    36181 tagccatata ccaatagtat ttctaagaac atctaattgt accatcaata aagcaactgg
    36241 aatacctata gagattccta cagatgcttc ttgcttagtc gtaatagtta taaatgtggc
    36301 tactatactt gctgtttgat aatcaggtat tgatgctcca ccaaagttac taatacctaa
    36361 tgataatagc tgtaatgtac ctccaatata taaccctgta tttatatctc ctaagataag
    36421 accagtaata aaacctgctg ttactggttg atatgttcca aacattgttg aatttttttc
    36481 atagtttata aaaaatccat atagtacgat taataataat tgccataatt gtggctccat
    36541 tatgatttca cctctcccaa aatatttttt agttctttaa aattataact ggaatcttgc
    36601 tttaggaaaa taggaatttc ttccagtggg cattcaactt cataagtttt cccaccttca
    36661 taactaactc cactaaatat attttcccat gtatgtcctt ttggtaaata tacttttcta
    36721 cttctatctt tataattcat tattggagct accaaaattt catctccaag catatatgta
    36781 ttatccacct cccaagtttt atcatcttca ggaaattcat aaaataaagt tctcataact
    36841 ggtgttccat cttcatgcgc ttctttcatc agttttttta aataagtttt taagctctct
    36901 ctaattttta tgaattttgt aagaattact tcaacttctt caccataaga ccatatttca
    36961 ttaggagctc cagttaccat tgagcctcca cctttatttg ataatggttt actatgaggc
    37021 aatctatctc catgcattct caaaattggt gaaaaagtag catattggaa ccatcttacc
    37081 ataagttctc taaattctgg gtctttagga tttcctccat ggaaacctcc aatatcagta
    37141 gtccaccatg gtatacctgc cagtcccata tttaaccctg tatttacttg attattaaaa
    37201 gcttcaaaac tagaatcaat gtcaccagac catactaaag ctccatactt ttgagctcct
    37261 gcccaagctc ctcttacaag agttacaaca gactctatgt cattatgtaa accatcataa
    37321 atcattttta aataatcaat aggataaata ttaccacaac ttaaaacatt tcctttttta
    37381 tatctatagt tatcaaaatc atacacagaa tagccaggtt cagctacatc taaccaataa
    37441 tagtcaatcc caagttgttt ataattttta tctattctat cccaaacata ttctcttgca
    37501 ttttcatttg tcatatctac aaagactgta tttccttgaa tttgcattgt cattctaaca
    37561 ccacgattaa cattgactaa atagccattt tctaaataat cattgtagtt ttctgcatca
    37621 ctttgaactg taggccatac agatactatt ggttctactg aatactcttc tttcaatttt
    37681 ttaactaatt ctttaggatt tttccaataa tctaagtcaa atttatattc accttgctta
    37741 ggccaatgaa aatagtcaat tgcaattgat gaaagcttaa ttcctctttt agaatattcc
    37801 ttcacaacat ctaaaacttc ttctgaagtt ctatatctta gtttactttg ccatagtcct
    37861 aaaaggtttt caggcatcat aggaacagtt ccagtaactt gagaataatt tttatttaac
    37921 tcttttgggc tttctccaca agtaatccaa taatctataa aatttgtaga aaacatcttc
    37981 cattctgtca tatttttagc aaaagatact tttccaattc ccggattatt ccataaaagt
    38041 ccataaccta gactagaaat ataaaaagga actgatattt gagaatttct ttgggctaac
    38101 tccaaaacag tattctttaa atctaaaaat ttatgttgat attgtcccat tccaaaaatc
    38161 ttttcagaag gctcagattc aaatctagta gttacttcaa attctccact atagcttggt
    38221 cgatattctc ttgattttaa ctttagagta gagttaaagt ctttggtaat ctcaattgtc
    38281 cctacatctt ctccaccatc atcatgtttt acagctctta atcgaatata ttctttcaat
    38341 aatatttcat ttttatcatt ataaaaagta attctatctc tatggtctaa gacagctttt
    38401 atctttccat ttttaatgat tgcacttcca tcttcatttt tattaattgt aatatcatct
    38461 ttatttaact taggtttttc gttaagagca tagttttcat caacaaaatt ttggtctaca
    38521 aacgacctaa tacgtaaaga gttttttccc catgcttcta ttcgcaatag ttcattgtca
    38581 aatctttttt caatatagtc ttcagatatt tttatcacgg ctacctccta aatcaatggt
    38641 ataatattct atctttgtgt agcttaagtt aaataatgtc gtttagtatc gttatttata
    38701 aattaggttt tatatataat tcatttgtac attaaactaa cttaccaata atatacttta
    38761 tttgactttg tttgtcaatc gctttccgga ttttagtaaa attttctaat atattgctgg
    38821 aaagtcgttc ttaatatctt ttatttatac ttttaatatc tgtgatgata cctatataca
    38881 tctagttttt ttaaaacaca tacaggaata acatttgcct attatgtaga taatatcgga
    38941 cttgaaaata tgtatagtga ccttataaat acagataata atatattaga tattgttcaa
    39001 aacaatggat tttataatta taaataattt attaaattat ttaagaaaat atacaattgt
    39061 ataccaagtc aaaaacgaca acaaataaat aaaactaaaa aagatgttgt ctcaaaatat
    39121 agataaattt atttttcatt gctaaaatga ttaaaatata tttgatttaa tatacttgat
    39181 ttaatataaa aaaagagtgt ctcataaact aaaaagttca cttttagaca ctcctttata
    39241 tatattatct acttcttaat tcatttatta cctctctaca ttttctttca actagtggat
    39301 acatctttat aagtactaat tactccactt aaaaatgatt caggtactgt ccatcagtca
    39361 tatttttctg ccaaatataa tggtgtttca taatgagaca ataaatattt atatctctac
    39421 ttatcttctc taagctcgtc aaatccaact ataggtatat ttaaattata ttctttaagt
    39481 agcttttcta gctcttctat aaaaatacct ttcccatcca ccatttgtat atcatttatt
    39541 ttatccatca attcattgca accacttaac tcaccaaacc aacgtttaga actacatgtc
    39601 ttattataac cacaacttgg actgccatct attgcaatga tactttttat atcataatca
    39661 ttttttaaat attcatcaaa ctgccttaca tgaggtatta acatttgcct acattgttct
    39721 ctaaaaaaca aattgtcaaa ctgttctttt acatgtcccc acctatttat tccatacata
    39781 atcatttctg ggcatggtag ttgaattatt ccataccctt tatttattaa atctatcgct
    39841 atattttgtg ctcccttaaa ttctgacaat ccctctactt tagaattaca atttaatata
    39901 caatgacata ctactacaat ctctctattt ctcttcataa taatctcctt agttattctt
    39961 aattttaatg atactacata ttttgataat tatattattt atttgttcta tatttccaat
    40021 attctatata gaaatataca attagtaatc ttttataatc tatactatga taaatgtata
    40081 tattttttta ggaggtatta taattggata ctaaaaaagt cacattttct tcaatgtgca
    40141 tagttattaa tattgtctta ggtatggtta tatctatgat aaatatacca ttattatttt
    40201 tagatacaat tggtactgta cttggggctg tcgtattagg tcctttttgg agtgctctta
    40261 ttggtgggtg tacaaactta gttttaggtg ttatatcagg tcctacaaat ataccttttg
    40321 cccttgtaaa tattgttctt ggtcttattg ttggatatat ttctaagaaa aaaggttttg
    40381 gttataaaga agctattatt acaggagtaa ttttatctat tgtttgtcct ttaattggta
    40441 ctcctatttc agttttattg tttggtggtt taagtggaag tggtgctgat ttattggttg
    40501 gttttttagt tcagtctggt cagaagatat ttactgctgc gttctttcca aggattctta
    40561 gtaatatagt agacaaacct ttgtcttgta ttatggtggt atattttata agtaaaatgc
    40621 ctaaaggttt tataaaacaa tatagtaaaa atacttctag ttcatattaa taaatcattt
    40681 attatgtaag atttattact ctttaaaatg ctatatactc atttttatat aacattttta
    40741 ttaataattt aattagatag tatttgtatt attttaatta aacgtaacct cttgatataa
    40801 atttgagcta taaatctata tcaagaggtg ctattttatt tttaatataa ttaatattct
    40861 attacgcaaa aaatacatat atttcattat tttatggaaa atattacttc atttaactct
    40921 atatcaaact cattaagtaa aaatctaatt atatttaatt tagcctctgt atttaaattt
    40981 gtttctaaat atatattttc tgatatttta ataccttttc ttaatttata tgcatctcta
    41041 gacttaatat tatctataaa atctctttta taagtcttgt ctacaatact gttaaacctt
    41101 acagaatcca aatcatataa agtaagagca acttgttcat aaaattctgt ccaattttta
    41161 gccttatatg actctcctaa tatactaaat gatactatac tttcatttgt aaaattaaca
    41221 tcatcatcct ctaacgtaaa tatattttca ctgttacttg gaggttcata tgtaacactt
    41281 ggatatttcc aaatttctac agctctatct agtaatatct tagttctatt ttttatttct
    41341 tcttcattcc atttatctat agatgaaata tatttattta gataaagcct actatcttta
    41401 aatccatctt ccatttcttt cttttcttca aatgttttat tacttagttt tgaattatat
    41461 cctgtcaaag ttaaatttcc aattgtatgt aaatatttat catgtatctc cttatagtta
    41521 tctcctagtg attccttcca tttatttgtt aatgtctgtg gcattatatg ctctatattt
    41581 agcatattat tattgattaa attttctaaa tcaacaattt ctttattatt ataattctct
    41641 aacctctcaa gtatatataa cttattcttt gacttagtat tatatatatc tttagtttca
    41701 aaagcatttg aaaattcact gtcagtagga aatctttgag atgatttctt atttataaaa
    41761 atatatctta atatattaga atagttttct ttataatcac taaatttttt aatttccctt
    41821 cctaagttca taaatacttt attcagtgca ttaggaggta catcacatac tattcttctt
    41881 aatataaaac attctactaa attaagggat tctacaagta cttttttatt tattatacct
    41941 tcattataat catcaaataa ttctaatata aacggatatg atacaaatat ttcaagtttg
    42001 tttatccttt tcaaaacttt gtttacatca ttatcatcag tacatgaata agatatctct
    42061 ctataatagt tagaaaattt aagtaaatct tttaataaaa tttctatatc tataccatta
    42121 tctgatacat accttttaaa actaaaatat actttatttt tattcggtat acttctctcc
    42181 tttatagtca aatagtctct tataaaacta cttacgttgc tacttgtatt tttttcaatt
    42241 ttataccaat aattattata aaattcctct tgtaacttag agcttctacc cattaacaca
    42301 aagtttctta ctctatcagc ttcacttaaa tctaagccag ttgaatttag actttcaaag
    42361 attaattgag ggtcatcttc accatttttt aactctattt ctactatagt taatttctgt
    42421 atagcatcaa acaaatcatc tattgatata ttatcttctt ttattctatt ataaaaatat
    42481 aaataatttg aaactatatt agaatttcta tctgtattca tttcttcttc aaatagttca
    42541 tagtacgctt ttctatcttc tgctattggt tttaacttta tttttccatc tttatctctt
    42601 gagtgcttgt ttataagata acactcctta atctgttctt ctgttgtaat aattcctttt
    42661 gattccccaa actcttttat tatttgacac atggcaatca ataatattga cacagtagtc
    42721 actctttgtt gtccatctat tattaaatat tcttttccca tactatatat agatacaact
    42781 gaccctaaga aatgagttct aaatccagaa tctattatat cctctaaatc atcaaacaat
    42841 cttttacatt gttctttctt ccagttataa tttctttgat atacaggtac tacaaaactt
    42901 ttgtttgacc cctctaaata actaagaaat tcaatttctc ctgctttcat attaactccc
    42961 cctataagtt aaataaattc cattcataac tccatgtatc tatatattat atcaaaattt
    43021 tgactcataa atgtatatga aagccttatt atataccttt ttatacctgt ttttatttta
    43081 ttaaagtaaa tacatgatta ttctataaaa tatacaaata cttaatttta aaaattatta
    43141 tttaatcttc ttcatgagta attcatagtt atttatcaat taaaaagaga tattgcataa
    43201 ttattcaata cctctctttg tatatttaca ttatccatat ctagttatct atttcaaccc
    43261 aatattagac tacctactaa taaatttatt ctctacatca ttaacaataa ttttgcacta
    43321 aataacatca ttagcctatc tctgatgcat tttctttaat tttatttata gttttaatca
    43381 atttatttct ctcttcaata tgattttcaa ataaatcaat tatacttcca acagttctaa
    43441 atgggtcttc catcaacact ttgttatcct ctataaatcc attcttgact acataatcga
    43501 ctataagttt aacaaaatgt atttgcttag tattaaagct cttattattt aaaaactctg
    43561 aaaaagcttc atttgcagct tctctatcca atcccactag tcttctcact aattggctta
    43621 ctggagtatc tccaaactcc ttcttataat catcacaatt acctaactgt tttaagagta
    43681 tttcctccaa cgtttcaaca tcttgctttg ttatcttttt attatttctt aatttaaata
    43741 ttgctaattc atctttatgg ctatttaaat aatactctac cttcttttta taattcttaa
    43801 gattgtttgc attatataca gaatcatttc tatcttctgc tacaatcata tcttcaaaac
    43861 ttgtataata tatcttttga ctagactttt caagatactt aataagctct cttaatgata
    43921 tacgtacttc ttctacctca aatatatctg aatcttccca aaaatcctct gtcattgctt
    43981 tttcaatagt atatttttgt tgctgaatct gtggtatagt cccaagtttt gaaagttttt
    44041 ctgctgtagc cattacatgc cttatacctt tacttgcatt attattttgt aagtatgcaa
    44101 gttgtatatt atacataact acatcaaatc ttttagccaa ttcatcatca ctatatgaag
    44161 ttatgagtgg tgatatatat tctcttatct cattttgtgc tactgctcca atattgctcc
    44221 aaacattttc atttttatac ttatgtacat aacttaaatt catcctaact atataactat
    44281 cctcatttaa agcttttaca gaagttataa gttcttctaa caattctttt ctaagttctg
    44341 catactcacc ttctatatat ttaatatctt gaagttcttt aaccatactt acctttatat
    44401 taaataattt ttcagtaagt gtttctgttt tatttccctc aaatccttta ggattaaatt
    44461 taaaaaattc aaaattatta caaaaatcaa atattaagaa tctttcctta tccatatcaa
    44521 cacctaataa atctggacat aatctagttc ctctacctat catttgccaa aacttagtct
    44581 tacttctcac tttcttgaaa aaaacaagat ttagtatttc aggtatgtca attcctgtat
    44641 caagcatatc tactgaaact gctatttgag gtaatttatt cttatcagaa aaatcatcta
    44701 ttatagaatc tacataattt atactatagt caactgcttt tacaaagttc ccaccatact
    44761 ttggatacag tttattaaat ctttcaacta ttgccctagc atgctttgta ttctttgcaa
    44821 aaattatagt cttaccaatc ttttcttctc cttctatttt caacccctct gtcattagct
    44881 tatttaaaac taaatctatt gtgtcagaat taaatagcca ctcatttact gcattattcc
    44941 ctatttcgtc tccaatactc tcatcatcat taaatgtatt ttcatattct tccttctctt
    45001 catcagaaag ctcatcatac ttaattccat cttccataat cttagtctta aactcaatac
    45061 tagtataatc tactaaatat ccatcctcga ctgccttatt atactcataa gcatatgtag
    45121 gtactccatt ttccatgtca aaaactgaat aagtattttt atctatctca tcctttggtg
    45181 tagcagtaag acccattaag taagaatcaa aataatcaaa gattgactta tactttttat
    45241 aaatacttct atgcgattca tctattataa ttaaatcaaa atgaccaggt gtaaacaatc
    45301 tctttccatc cttagacttc gtatcatcaa ttgcattcat cattgttgga tatgtagaaa
    45361 atatcatcct agcatcttct gggctgtctt tgctatccaa taaattacat aacgccaagt
    45421 taggtaatag cttagtaaaa ctttttttag cttgctttac caatgctttt ctatctgcta
    45481 gaaataatat atttttaatc caattatgtc ttgaaagtac atcaactata gatatagcaa
    45541 ttcttgtttt tcctgtacca gtagcacata ccaaaagagt tttgcgttgc ttattttcaa
    45601 gagcctcaca tacagcccta atagcttctt tttgataata tctattggat atttcatcat
    45661 ttattgttac agaacttaaa gacttcttac tctttcttct atctatcata agttgtaatt
    45721 ctgatttttt ataaaatcca taaactttcc tatctgaata gtcatcccaa atatacatat
    45781 caaaaccatt agtcaaaaat attaccggtc tttgactata tctcttttcc aaacaatctg
    45841 catataattt agcttgttgt tgaccaattt tcgggtcttt actcgttctt ttcgcctcaa
    45901 ctactgctaa tggcttacca ttttcaccat aaagaacata atctacatat cccacaccac
    45961 tttcattagg cataccttgt acttctattt cttcccatat atcttttcca aattcccaac
    46021 ctgcaagctt taattctata tttatatatc tttttcttgt ctcaaattcg cttacttcgt
    46081 ctatcttgaa atcatagttt acagtattaa cttttctctt ttcagttagt gactttctta
    46141 attcctcatt ttcttttatt acttcttcaa gctttttatc ttttgaactt aatctctcat
    46201 aaagattttt aagttcgtct ggtctcgtcc ttttctcttc cccatgaagt aataaatctt
    46261 cattaaagtc ttctgctgta tattcatctg aataacaata gtctatccaa ctaacaaatt
    46321 gatgcaaatt gttaagtgaa agtattgctt ctcctctctc tatgttcgca ctagtatgta
    46381 cagataaatt acctaattta actatatatt ttaataaagg taacatatca tagtctataa
    46441 gttctataaa actattatta tgaatcaacg tactaagatt atcttgataa ggcaatacta
    46501 aatcactatc attagcatat agccatttta ctgcaagctc taaagctctt cttgttatag
    46561 ttgcacaagt agatgggcta actagtatac ttttttctgc ttctaagcaa gcagtattaa
    46621 aactattgaa atttttcttc ttttgtaaaa aatcaaaatt acccaaggct tttatccccc
    46681 ttttgtccct tagttaaaat aaatctctct aaaaactatt tcttacagct gtttcttata
    46741 ctaacaaata cttcttcatt ttctgtaaac aattcgtaca tatcttcaaa ctgtggtata
    46801 tcatatccat gagaatcatc atttctcaat tttctaagtg tttctataac tatagaagaa
    46861 tttttaggta ataaattgtg atactcacaa gctaaaaggt agtcataaaa gtttttagat
    46921 tttatgttta aatcaattga tttataatac aacattgctt ttgttaattc tagaaatgat
    46981 accatatagc ttttaaagcc ttcttttatg tatctagccc ataactcagg catttcttcc
    47041 ttatcatata agattttgaa gttttgcagg tcatacaagc aagaaccaaa atccctattt
    47101 acttcttcta ttgagttcca agataatttg tttctaatta ccatacatgt ccctccaatc
    47161 taagatatct attacatcac tgttttcaaa atagaattta tttatataat ccttaaaatc
    47221 tttagattta taaataactt caccttctaa aatagctttt ttaagtgcta ttgtataatt
    47281 atctgtaaca atttttaggt ctacatcaat gtctaatata tttcttagag cttctgtctt
    47341 agttgcaagt tctgtaattg gtactttttt gatgggaatc caagctatgt ctatatcact
    47401 ttctgatgta tgtttatctg ttccataact accaaatatt atgattgcta gagtattttc
    47461 ttttggaaat acatttatta ttgagttttt aatctcattt ggtatatttc tcatttaatc
    47521 acctcttgtt tattaggtaa tattgcttaa ttgaatttat atccataatc ttttaatcta
    47581 tttatacata tttctctttc ttcatcagta aacaactctt tatacttttc ttttaatact
    47641 aatacttcta atgataaatc taatctctta cactcccata gccttgtaaa tccttcagta
    47701 gctccttctt tattgattaa ttctttagca gctaataagg ctcctttgtt atttatcagt
    47761 tgtaaaaatc ttgttggctt atagttacat tgtaaatcag cttctttata gatatttacc
    47821 atgttatggt ataaatctag ctctatttga ttcatagatt ttattccccc attttaataa
    47881 ttgtatttta gttgaataac tatcctttaa aagctttttg cattaatgag ttaaagttgt
    47941 cttctagttc ttttagactt gtttttattc ctactttcaa tttgtctact tgattaacaa
    48001 actcttcaaa cttattttga agttctattg atggtactgg tattaatatt ttttgaagtt
    48061 ctttgcttct aattccttgt gcagagctac cagttttata tttatctatt tctaccctaa
    48121 aagcttttgt ttgcatatat tgtgctaaaa aagcattatt taaaattttt ttatctccct
    48181 gaattgttat aatcctttga cccatagcaa acttttttaa atcctttggt atcctacata
    48241 catttccaaa tgtatgacct tctgtaacaa aaagtacatc tccagctact ggaaaacctc
    48301 ttttcatcca agaattatag gtgttttcag atatatattc attaatatat ttaaatacac
    48361 cattccctac agattttgca tttattattc taattccatt ctctgaaaga attggagttt
    48421 taccacgata atcaataaaa tttgtacaat ctttcaataa tacaaacttt tgttccttaa
    48481 aatttccaaa catttcaata aatcttgatt taactaattc atccaatgct tctatttgct
    48541 cttttctttt atctattaac tcttgagctt tatctaaaac ttttgatata tctttttgag
    48601 cttccatttc aggtaaatct acttttaaat tttttaaatc attaactgaa aaacttgctt
    48661 gattaactga tttttttatt atccttggta actgtcttct aaattcatta ctattaaaaa
    48721 aataatttaa atactttgga taacaaactt ctttatctgg tcgtaaacat aaaagattca
    48781 ttccatgtat aattttttta tttatatctt catatattgc acttttccct aaatgttttt
    48841 cactattaat atgtgacatt agtatatctc catttttcaa taaatagtct tctaattttc
    48901 ctaactcttt tatgtcagca tatcccattt tattagtatc aatataagag tttgctatag
    48961 tttctattct tgtaattgga tatccaaatt ttgtatcaaa ttgtttaata ctagccccat
    49021 ttctaataaa ttcaaaaact tcattcaatc tatattccat actctacacc tcaagcattc
    49081 tttctaattc ctctaatcca tctacgattt ccttctctaa ctccctaact ctacctataa
    49141 taacactagg agcatcataa actacttcct catacactac ctctttatac ttattaatag
    49201 ataaatcata cccattctct cttatctctt ccacatcaac aaaaaagctt tgctctgttc
    49261 tttttctatc tacttcacca tcaagattat caaatctctt aataatatcc tctatatcac
    49321 tatcctttat ctcatttctc ttatcatcca aagaataacc atcagctttc atatcataga
    49381 accatacctt atcagttcca cctgttcctg ttttagtaaa tatcattata gctgtagata
    49441 ctcctgcata aggcttaaac actccacttg gcattgatat tatagcttcc aatttatgat
    49501 tatcaactat ttcttttctt atcgatttat gtccacctgt tgaaccaaac aatactccat
    49561 ctggcactat acatgcgcat cttccaccaa tttttaaaac tcttaaaaaa agtgccaaga
    49621 ataataactc tgttttcttt gtcttagtca cttttaataa atctgctgac actgcttcat
    49681 aatctaaact tcccttaaaa ggaggatttg ctaacaccaa tgtaaactta tctttatctg
    49741 tattaacctc cgataaagaa tccttatact ctatattagg attgtcaacg ccatgcaaca
    49801 tcatattcat agcacctatt ctaagcatag ttctatccat atcaaatcca tagaacatac
    49861 cattattaaa atgctccttc agcccttgca ctaagaaaag acttgaatga ttatccctta
    49921 agtattgttg tgatgatact aaaaaacctg ccgaacctgc tgccgggtct actataatat
    49981 cttctggtgt tggtttaata agtcttacta tcatatctat tatgtgtctt ggagtcctaa
    50041 attgaccatt agtacctgct gtagccactt tggataataa atactcatac aaatctccct
    50101 ttgtatctct atccttactt aattctaaat tactaatacc atcaactatt ttagataaca
    50161 taagaggcgt aggaatttta aatattgcat ctcccatgta ctttgcataa gctgattctt
    50221 tatttccatg taattttttt atgaaaggga acacttcatt ttgtactatt tcatacattt
    50281 tttctgaatt tccttcatta gaaaacttac tccaccttaa atgttgatgt tcatcatcaa
    50341 atatcttttc aaaagaaaca cccaaaagag ttgcttctgc ttcatttttt gtttctactt
    50401 catccaatcc tttaataaat aaaagatatg taaattgttc tataacttct aatggattag
    50461 ttaatccacc agtccaaaaa gtctcccaaa tcttgtccac tttactcctt aattctcctg
    50521 taatcatata tgactttccc tccagtgttc ataaaataat ttaaatatat attttagtcg
    50581 tacgccttaa tagttagtgt cttatgttaa atccaagttt ttactacaca attattaaat
    50641 tatttttcct atttacatat tttagctaaa aaactaatgc aatactctta ttttatgatt
    50701 attatatata ccatacaaaa ttattttatc atatatccat catagaagtc atctacctgg
    50761 ataactctta ccatattata actttttaat attaatttaa acttagaaag aaatttttta
    50821 tttaattata tcatcttcct tatttcaaac ttctcaatta caatcttaat caaaaaataa
    50881 aataagatgc tgtctcaaaa tagatataat cttctttttt attgtcggaa tgatgaaaat
    50941 atatttaatt tcatacaaaa aagagtgcct catgaactaa aagttcattt tgagacaccc
    51001 cttaatttaa tcttacttat tctttccctt tattattaac acttcactat ctctattgct
    51061 tttcctacac atccacaaac ttccatccta ctcttaacaa aatctttaac tgactctaaa
    51121 ccttttttac catatttttt agggtcaatt acctctgggt cagaattaag cacatcctta
    51181 accccattgc tataagcaat ccttaattca gttgcataat taaccttgca aatccctctt
    51241 tttatagact ccttaataac ctcatctggt attccagacc caccatgtaa tactaatgga
    51301 actgatacaa cctctctaat ttcagataat ctatctaaat caagttttgg ctctccctta
    51361 tatagcccat gtgccgtacc tattgctact gctaaagatg atacccctgt tctctctaca
    51421 aactcttttg cttctaatgg gtctgtatat gctccaccat caccaccatc taaatcgtct
    51481 tccttacctc caactttacc taattcagct tcaacaggta tatctgaagg catacatgca
    51541 tctacaacag atttagatat tgaaatatta tcttcataac tttcatgaga accatcaatc
    51601 ataatagaag tatatccaac tctaagtgcc tgcatagcta gtccaaagct tgaaccatgg
    51661 tctaagtgca ttgctactgg aacacttgcc ttctctgatg ctacctttac attcgctaaa
    51721 taataatcta gtcctgcata ctttattgtt gaaggtgttg tttgcaatat tactggtgat
    51781 ttaagttctt cagcagcctc tattactgcc ataaccatct ccatattttc aacattaaat
    51841 gcacctactg cataatgccc ttcttgtgca tctaataata tttgtttagt tgtcactaat
    51901 gccataattt ctcctcctat atgtttatac tgatttaatt tcttcgttat ttaattttga
    51961 tactatttct ctacttgttt tgctatttaa taactcattt aaaaattctt cattcattaa
    52021 ttttgaagat agttgagata atgtttttaa gtgtaaatta tcaccattat ctgtagctgc
    52081 tatcataaat ataatatgtg ccaagcttcc atcttctgat tcaaagtcaa acccttcttt
    52141 tgatagacct actgctacac gtggtacctt tactgcatct gtttttgcat gtggtatcgc
    52201 tatccccata ccaaaacctg tagatgatat ttcttctctt ttaaggattt cttctttaaa
    52261 cttcttttta tctaaaagaa cactagattt atcaagtatt ccaatcattt catcaattac
    52321 atctgtttta ttttttctct taacatctaa aattactgtt tcttcgctat ataaagagat
    52381 attattagat acgttttccg attctgcact ttcattttta tgttcatctt ttgttacatt
    52441 tgtattttct atagtatttt tctcatttac tactttaggt gtaaccatca tataaagtac
    52501 agcacctact aatgaaccta caaatataca ccctacccat aaaagtggct tattgactaa
    52561 tcctagaacc aaaaaccctc catgtggagc tggtacttct attttcatta tataagttaa
    52621 aattgatgat attgatgatg caatcataag tactggcaac acttttaatg gattttttgc
    52681 tgcaaaaggt attgccccct ctgttatatg agtactacct agtatataat tgattaatcc
    52741 tgctgctcta tcttcttctg taaatctatt tttaaataaa gtagatgcta ttgctattac
    52801 caatggtggt gttatacaag ctgcagatac acctgccata aataaataat ttccctgtcc
    52861 tagaagcata gttccagtta catatgctgc tttatttact ggacctccca tatcaaatgc
    52921 tgacatacat cctattacta ttcccaaaat tatagggctt gaattttgta accccgatag
    52981 aaagttcatc atagcattgt taagtgctga acatggccca ccaagtaaca acattgctac
    53041 acccacaaga cctacgctga caataggaat tataaaaatc gatttaagac cttctaattg
    53101 tcgtggtaat tttcttaaca aatgtacaaa tagtttaact aagtaacctg ctaaaaatcc
    53161 tgatatgatt ccacctaaaa accccgaacc tgtatcaaat gatatcattc ctccaacaag
    53221 tcctgccaac ataccagctc ttcccgatat agattgagct ataaatgctg ccaatacagg
    53281 aaccatcaag ttcatagaat atccaccaac agattttaat gtagctgcta tttgattata
    53341 ttgttctgaa tttgggtcaa atgaataaat cccccataaa aatgatatag cagtaagtac
    53401 tccacctgct actactaaag gtaacatgtg agatacacca ttcattaagt ctttatacaa
    53461 cttttgacca aacgataaat ttccttcttc tgcaatttta ctgcttgata agtttccttt
    53521 tctaatagct acttttccat caatacatct ttgtataagt tcattagctt tatgtatacc
    53581 ttctttgaca ggtacttcta ttactggctt tccattgaat ctgtccatat caacattttt
    53641 atcacaagca actattattg catctgccat ttcgatatct tttgctgtta acttattttc
    53701 tacacctata gctccattcg tttcaacttt tatgtcacac cctaattccc tggctgaatt
    53761 ttttaatgct tcttctgcca taaaagtatg agctattcca gttggacaac ctgttacccc
    53821 tagaatcatt ttctttccca tttttatacc acctttctga ctcttatatt ttttatataa
    53881 tcttccacat tctccaaatt acctatacca ttactttcag ccacacttgc tcctgttgct
    53941 gctgaccttt ttaatgcttc ttcaatatgt tctggatttt ccaaccatat acttaaaaaa
    54001 gcagctaatg cagaatcacc agcacatgca gagctgacta ctgtaactgg ttgagcacta
    54061 gcataataaa ttgattttcc attataaaaa taagaacctt tttctcctaa agttagcaat
    54121 atattttgag caccttttaa atgtagtaat ttaagtacat ccttaatatc ttcttcatct
    54181 cttacaataa ttccaaatat atctttgatt tcttcatcat ttggttttat caaatatgga
    54241 ttatactgta gtaactcctt taattttggt gaacttatat cgagtattgt ctttatactt
    54301 ttatttttac aaattttaaa tatatcctca tagtaattat catcaatacc aggaggtaga
    54361 cttccactta ttgataagta acttatatct tctaatgact gtatcttatc tagcatatct
    54421 agtttttgtt tttcgtttac atatgaccca gagtttacaa atttaaattc atcacttcca
    54481 tcatttaaaa atatatttat acgagttgta tcttctaacc aagtaggcaa tacgtcaaat
    54541 cctctctttt cgctttcttc aactatatat tttcctgaaa atcctccaaa aaatcctaat
    54601 atcttagatt ctataccata atgacctagt acaaaagtta catttaatcc ctttccatta
    54661 ggagaatata cagcatttga tgtacgattt actaattttc tctttatccc attagtagat
    54721 atattcatat ctattgcagg attcgtagtt aatgtatata tcattgtctt cccccttgct
    54781 tgtgctgtgt atgttttcat tataataaaa aagtctatga aaatcttttc acaaatagaa
    54841 aatcgatttt catagacttt tcaatttaat tttcagaatt attatatctg accatataat
    54901 ctataattat cctagatata atatacaagg gcaatctgga agatacttca tattcagaaa
    54961 ttgatatatg ttcatgtttg tatcctacaa tatataaatc cgaatacttt ataagttttg
    55021 cactttcact acaacagcaa gttataacct tagctccaac taaattggca ttctgtgctg
    55081 attctacaag ctctatggta tttccattca atgaaaatat aattataagt tcgtcttttt
    55141 ttattgattt agattttatt ttcattatgt tggggtcatt tataaaaaca acattaaaat
    55201 caagtaattg caatttaaga ctaaactctt ttgctacata ttcagtaagc cctcttgcta
    55261 aaatatatat cttactagat ttatttatag tttttattat attgattagt gtagttaaag
    55321 atatttgttc tataactctc tgtgcttcta taaaggattt atttattata tcccccatat
    55381 tttgtatatc atcattttca tcttttactg ttaatctata cctaagttca ttgaatccat
    55441 ttaaaccaca ttttctaatt gctcttgaaa cggttgctgg agatgaatat gtttcatgag
    55501 caatctctac tatagataat tctggtaata ttgattcatt ttcatttata aatttaatta
    55561 tttcaagttc cgtcttcgtt agattttcag aattactttt gtttagctca attatcatat
    55621 gttatctccc cttatataag ttttatttgt ctaaatttat cgagtaatat aatatattac
    55681 ctcttaacta cttattttta tatacaatta agatttagtc aatgtctata tatgtaaatt
    55741 tataatataa taattttttg cttaaagttt attatgttat cttatagcat tttaaaataa
    55801 aaaagaattg tacctctacc aaaatttgga tgaagtacaa tagatattcc tcatactgat
    55861 atgtttatga ttaaaagtat aaatataaat ttcgctatga atcatataat taataaatca
    55921 ttttatttac aattataacc ccccttataa aactatatta ataatatata cagtatttat
    55981 aaggggggtt gtttatattt aaaaactatt tacttttctc ttaattcttc tccattagtt
    56041 cttattacat tttgatacca ataaaaacta tcttttttat aacgttcttt acttccattt
    56101 ccattgttat ctatatccac atatataaat ccatatcttt tttccatttc ttgagatgaa
    56161 caacttacta tatctattgg tgaccacata caataagcta atatttcggt tccatcagct
    56221 atagcttcac ctatttgttc tatatgtttt cctaaataat ctattctgta actatcatga
    56281 acttttccat cttcaaattt atcatgcatt ccaaatccat tttcagctat cattattggc
    56341 ttttggtatc tatcataata ttgagataaa gtattgtata atccttttgg gtcaattgcc
    56401 cacccccaag gatttgcttt taaatatgga ttctttatat tgtcagttgg attcatggtg
    56461 tttttacttg ctgatactgt tgtagaataa tagtatgata aagctagaaa atccatagta
    56521 ttttctttta agattttatc atcaccttcc tccataacta tatttatgtt attttctttg
    56581 aaaaatctct taatatagac tggatactct cccctaaaac ttacatcagt gaaaaaatat
    56641 tgtagcctat ttctttttaa agcaaatact acattttcag ggtcacaatc ttctggataa
    56701 gatgtacaat ctgccatcat catacctatc atcatatctg aatttatttc ttttccaagc
    56761 ttcttagtca aagctgtagc tatgaattga tgatgaatag cttgatatct agtctcttct
    56821 acattatcta cttggtctac acaaaatgca actgaattaa atgattcata atgtattaaa
    56881 tttatttgat ttataactat ccaatattta actttatttt tatatctatt tagtattaat
    56941 tctgcatatc taacaaagaa atctaccact tttctattag accatccttt atattttaat
    57001 actaaattca aaggagtctc atagtgaagt agtgttacaa taggttccat accattatct
    57061 attacttcat ttataagatt atcataaaac tttaatccct cttcattagg ctctaaatca
    57121 tctccatttg gaaatattct agcccaattt attgaaaatc taaaacactt taaccctagc
    57181 tctttcaaaa gctttaaatc ttctttgtat gtatgataaa agtctattcc actacgctta
    57241 ggataatatc cattattatc tttcatagca aactttattc tttctatagt catatcagac
    57301 tcataaggtt tagatatatc tctatcttta tcatacatat gtacatcagc taaacaccaa
    57361 cctttgccac cttcattcca tgcaccttct aattgattag ctgctacagc tcctccccat
    57421 aaaaaacctt taggaaactt acccaattta atcactcctt attttattta tttaaatcat
    57481 ttactattat ttaccttata ttctatagac tttactattc ctactaaaga catagttata
    57541 tttaactcgc tgaatatggt cataagagta tcttgagcat gtgcaaataa cagcgaatgt
    57601 gctcttttct ctccaccagc ttccccttgt ataatcttgg tttgagctct atgtgcttct
    57661 gtcataaacc cttttgcttt agctagtttt aaatcagcat ttctataatc aaacttttcc
    57721 aaatcattaa gagcatgttt aatttctgtt ctagcctcac ctgcacgaag tattatttgc
    57781 attgccacct ctactaattc ttcatctatt atatgttctt caattgtcat atttataatt
    57841 tcctttcaat ttctaaattt aaacctcttg gctctctaat tttatctctt ctttctcata
    57901 agctttaaaa aatggatacc atatcataaa tagcaatact atatttattg ctaaaacaat
    57961 aagacctcta acatcttgat ttaccgtaaa agtagatata ccaaaaggaa cataccataa
    58021 attaaacacc ttacttggaa ttgtcacaaa tcccatactc attgataagt aagtagttat
    58081 tgatattact actgttccta tccacatagg taacattaaa aatgggttcc atgccactgg
    58141 agctccaaat attactggtt catttatatt cattatagaa gggacaatac atgctcttcc
    58201 tattgctttt attcttccaa ctctggataa acacatcatt ataactaatg gtaatgtagc
    58261 acccaaccct cctaaagtta tccaacctgt ttgaataact tcgtaaacat atatattagt
    58321 tgctactcct cctgatgcta ctgctgctgc attagctgca attgcaccaa gttgaattga
    58381 ataagttata ggagatagta cccacccact tattcctaaa gaatatataa atactactaa
    58441 aaagtttaag agtacaaatc caggtaatgt ctgtgctata tctgatactg gtttaaatac
    58501 tctaactatt atttcaaaca tgtcaaagtt gagtccataa attaatcccc agcctacaaa
    58561 cattatcact gttataggta acatattatc aaaccacttg cttacaaaat ccggaagtgc
    58621 tgaatcttct ccgaaaaatg aaaaagaacc aaataaggac attattaatc cagagaataa
    58681 tcctgcaact agcgatacaa gcattccttc tcctccaaac ctgttgaagt taaatatagc
    58741 tccttcattc gtaatctctg gacgaatcat cattaacatt aatccagcac ctgcaagacc
    58801 agcgactaca ctcatacttt caaatttctt attcttcatt atttccatag gcaataaaaa
    58861 tgctataaat aatcctaaaa gtccaaatgt atattgattt attggactta aatcaggtaa
    58921 aaagcttatg taattcttca agacagaaac tatagttact aatgagccta caaataccat
    58981 tggcaaaact ttcattatag ttgattgaac tgattgtacc catatattct tagtcatatt
    59041 atttacaaca ggagtaaatt tttcacttaa aaaatctata aatttattca taaacactct
    59101 ccccataaat attttatttg tttgatatta gttctagtgc ttcttccaaa gcctttgccc
    59161 catctagtct tccatatgca gttttagata tacatgctac tggaacgtta tattcattag
    59221 ccttttgttg aatttcttcc ttcatataat ctaaatgtgg tcctagtaat aaacaatcta
    59281 tttctgataa atacttatct atctctgact cacttctcgc ttttatatct gcttctatac
    59341 cttttttctt tgcactcttt ctcatactag ttgccataaa acctgtactt gctcctgaac
    59401 cacacgccaa aagcactctt atatttttca taatgatacc tccaatattt ttatccatca
    59461 atttatttct taatgaactt tttattttat tatgtttata ttgtacttac caaataagtt
    59521 catttcacat aaatatattt cctaataata ggaaatcagt tactcttaat taaacatatt
    59581 aatatagtat aatgtatctt ataatacgta cattcaatta tataattatc atatcatcca
    59641 gattttattt taaaactatg cgagggaatc taatgaaaac atctaaaaaa gaactatttt
    59701 taaatttcat aaaaacacaa catgattgga tagattcatc tacattggct aattatctta
    59761 atgtctcaac gcgttcaatt agaaaatatg taaacgaaat taattccaat ggtgaattta
    59821 tattatcctc taaaaaagga tataaagtaa atctcaataa taattgtcaa accaaggttg
    59881 atagttcaga aaatatatca cctgataaca ggttaaattt aattttaaaa gaacttatag
    59941 ttaatagtaa tggaattaat atatttgatt taagtgaaga cttgtttgtt agtccagcta
    60001 ctattgaagg agatatagtc aaagctaata aatttatagg aagttataat ttaaagataa
    60061 agcaatcgaa atttttattg aaactaattg gaaatgagtc tgcaaagcgc aaattaatga
    60121 gctctataat atttaaagaa acgggaagtg attttttaag cttatttgat gtacaaaaaa
    60181 tatatcaaga gtataatttg accaaactga aagaaaatat aatatatata ttaaaaaaat
    60241 acaatttgtt tataaatgag tatgctataa ataacatact tcttcattta atgataacta
    60301 tagacagaat aaaaaagaat aactacatag aatctgtcga agtagtaaac tacatagata
    60361 ataataatga tataagcatt tcaagagata tatcaaattt tttagagtct gaatacaata
    60421 taactttaac tagtgcagaa ttatactact tagtatttca gttaacaaac aaaaccacag
    60481 tcttaaatta tcatgaaatg gatactaagt cattgccaaa ttatatagat gaacattttg
    60541 ttaaattaac taaaaaaata attaaaaatg tatatgactt atactttata gatttatctg
    60601 atgatgaatt tgttgtaaaa tttactcttc atgtaaaaaa tttaatcagt agggctaaaa
    60661 ataatcaagt tttgagaaat caaatacctc agaagttaaa agattcctac cctctgatat
    60721 atgatatatc tgtttatatt tgtaatcaga ttcaaatttt agaaaacata gaaatagatg
    60781 aagatgaaat atcgtatata tctcttcatg taggttcatt ttttgataga caaaaattac
    60841 tagaagataa aattctctgt gcattaatta ctccaaatta ctatgattta caattcaaaa
    60901 tagtaagaga ccttgagaag agatttaatg aatccataga aattattcag attttttcag
    60961 atactcataa tcttgatttt gacaataagg tagacatggt tattactact ttaccaatta
    61021 gcgatagatg ccctatacct tttgtttatg taaatcctta cctaaataga aaggattatg
    61081 ataatattca aagtaaattt attcagatta aagatagaaa aaatatactt actgtacaaa
    61141 atcatttaga aatgtacttt agtgaatctt tgtttatgaa aaatatatat ttagatagtg
    61201 ctaaagatta tataagattt atgggaaata ttctgtacga aaataaatat gtcaaaccca
    61261 attatataga tgatgttctt ataagagaaa aaatgtcttc aactgcattt aataacaatg
    61321 tagcaattcc tcatagcatg aaaatggatg ctttaaaaac cggagtatgt ttaattgtta
    61381 acgataaacc agttaaatgg ggtgaggaaa aagttcaaat tatagctatg atacctataa
    61441 atgaaaaaga aaaagaaaag ttcaattaca tatttgaaag ctttattgaa atattatctg
    61501 agtggaataa tgttaaagaa cttactaagg cagataacta tagtagtttt atgaatagaa
    61561 tagcttatct tattcaaaat atctaaatca attaatttat ttccaatata tgtttcttaa
    61621 gttattaaca taaaatagat aagctgtcac actaaaaagt ctaaattaat atgtgacagc
    61681 tttttaccta atataccttg ttttaatact acatattttt tgactgttgt atactagtta
    61741 taagattgaa tatttgtgtt gttgtagctg tcatattctc actagcagtt gctttatcca
    61801 ttgcttcttc tattgtcata gctctattta ctatagaaaa ataagcatct ataccctctt
    61861 cattacattt aactgcatct tctgttgtgg ctccagccaa acctattact tttaccccat
    61921 atttttttgc cagttttgca actcctattg gagccttgcc catagcagtt tgattgtcca
    61981 atctaccttc accagttatg acaaaatctg catcttttaa ctcttcctct aatttaattt
    62041 cttctaatat tatttttatt ccagattcta attttgaatt taaaaatgct aaaaaagcaa
    62101 aacctaatcc tcctgctgct cctgctcctt ctacattagc tacatcttta cttaagtaat
    62161 ttttaactac tttggaaaaa tttctaagcc cattatctaa ctcctcaatt atttctgatg
    62221 ttgcaccttt ttgagacccg tatatgtatg cagctccatt tttcccaaac agcggattat
    62281 ttacatcaca ggctatttta aacttacatt catctaattc ctttaatcta ttttctattt
    62341 ttatatgtct tatttcattt aaaacttttc cacctaatcc tactaacttg ttattttcat
    62401 cataaaactc aaaccctaag gcttgaagca tacctatccc agcatcatta gtagcacttc
    62461 cacctatccc aactataaaa tttctatagc ctttatttat tgcttctttt attatttccc
    62521 caacaccata agttgtagtg tataaaggat ttctaagttc agtcggaacc aatgttagtc
    62581 ctgatgcttg agctatttct attattgctg tacttgtatt ttttaataat ccatatgttg
    62641 catccacttt tttagctatt ggtccagtaa cttctatagt atctttttta ccattcatcc
    62701 cttgaactaa ggcatctact gtcccttcac caccatcagc aagtggcaat atctttactt
    62761 gcgcatcttc tttaaccttc aatatcccct tttttattgc atttcctgcc tctattgaag
    62821 ataagcttcc tttcaaagaa tctatagaaa ttaatatttt catatttatc tactcctttt
    62881 tattactcct tattttaaac atataatttt ataagcttaa tttatctttt attttatact
    62941 ctacatctct ctttgtatac aacttatacc attaatattc ttttatctta taaaaaggga
    63001 gtgtctcaaa ataaatttct tagttcatga gacactcttt ttgtataaaa tcaaatatat
    63061 gtttattatt tcaacaatga taaggaggat tatctctatt ttaagataat tcctttttag
    63121 cactatttaa ccagtatagt tttaacttgg ttcattaagc actctacatt tacagagtta
    63181 ttatctattg atatagattc taattctttt tcatttaggt taatccattt agctgtttta
    63241 atatttttgt taaatactat gttagctgat tttgtttctt ctttagaatt gtaaaatcta
    63301 actactaatg cctcttgttt ttcagccttt tttacaacac ttaacacaag gtccttatta
    63361 gtttccttaa gtaaactata tgaataatct acttctattt ctgattgatt caatttcata
    63421 gcattatatg gcattttatt ataagtttgt atttttgtta aatactcttt agccatattt
    63481 gcaacatttg cttctagtgt agatttttca tgagtaacta ttgctaagtc tatttttata
    63541 tctcctatca tttgagaatc tggagtaggc aactttattc ctgatggacg acctgggcgt
    63601 cttgccattt cttctttacc taggaatcct acacttctaa ataatgttat agctattgtg
    63661 tcaaattttt cccctactat ttcaaactct cttgtactgt ttgtaagaac agctactcca
    63721 tgctctttgt cagacaatcc aacgaatgtt agcattggat atatagaatc tggtctttca
    63781 ctccattctt cctgttgcca aacttccata gcatcatcat acacacttct ctttatatgt
    63841 ccaaactgat tatcagacac agaaaacttt gaagctatat ttgttggtat ataagttcta
    63901 accctacaat ctcttgcttg gttatttatg ttgaatacta catctattat agctttatca
    63961 tttggaacat ttataactat atcaaagtca ataaatgaat ctgctctatt attttttcta
    64021 gcttgtatat cttttggtac ttttaatcta taatttatct ttatctcatt attaaatcta
    64081 tttttcttta tagtggaatt tgctactata ttatcgttaa atattaattt ctcatttgga
    64141 agtggtgaaa aatcatactc atctccttca tctcctccat tttccatcaa taatacattt
    64201 tcaaaagttt tatttaattt tttatcaaat atctttaatg tcccgttttc attaacttga
    64261 atagtataaa agtcattatc taccatgtca catacttcat aagctttttc taacatatgt
    64321 tcaacttctt ttatcatata cgccttatac cccattgcag gtattttatc tttaaagttt
    64381 attgtatata ccataaatga atcatagttt ccataatgaa caatttgacg gtctattaat
    64441 cctgcatcta ttacttcttt atgtaccact tcaaaatcca acttattatt atctttatca
    64501 aatatttcaa atgctttcat tttagttata acttgagcgc ttactatttc attcctatcg
    64561 taaggcatta agttaaatgc tactaactta tctaaagcca tttcacaact cattgcatca
    64621 actattcttc ttttgtaaaa tgttattaat tggtctactt tttcctcagc taagaaaaat
    64681 ctattcatta tttcatggtg aactttatct gaacaacaac atccaatgct gtcatgagca
    64741 tgatttttca ttatttcttt ccaaattaac tctattaatc catgatgata ttcaaatcct
    64801 agagaatatg caatagaagc tagtggctcc aatatgttgg ttatctttga ttctattcta
    64861 gcatttgctg attttatatc cattcttgtt gagaatatac ttctatgaac cctcatatat
    64921 ttcccatcta aaaattcccc ttttattgta tctatatcct catttttttc tagctcttta
    64981 aatatgtttt catatctact taagaaaaat tttctctctg gataacattc ttttaattta
    65041 tatataactt caaatatatt cttttgaatt ggcatttggt catgtccatt tggaagtatt
    65101 atatggtcag tagttgcacc cttatcaaga accggtaaat atttatccat tcttgttctt
    65161 agctcatctt cattcattgg tagatatttt cctattgcat aacctaatgg aagtatttga
    65221 accaaaacag aagacccatc atcactcttc caattaaact ctgttttatt agttcctttt
    65281 ctttcagaac atcctctcca aaacattgag tattttatat caaacccatt tagtatttgt
    65341 ggcatttgag cactttgacc aaatgaatct ggtaaatatc ctattttcat atattctcca
    65401 aattcatcac aatcttttat tccatatagt aaatttctaa gtatggattc tccaccaact
    65461 accatttcat cagtttgagt ataccaagga cctattatta gccttccttc ttgaactaat
    65521 ttttttattc tctccttaca ttcaggctta actgctaaat aatcttctaa tatagcagtt
    65581 tgaccatcca tcacataata tggatagtta tgattatttt ctaacatatc cattatttct
    65641 tccatattat ttacaagtaa tattctagat tcctcagttg agaagtacca ttctctatcc
    65701 caatgcatat gaggaactat gtgtacattt tttttcattg cttatcctcc aaaacttatc
    65761 tgataatatt ttctgtctaa ttaaaaatcc aataaaaata ctactgagtt tacaaaattt
    65821 tttaatattt attttatcac tataattaaa cctttgattt aaatatctaa taacgtatct
    65881 tttaatgtat ctttctttga tttttttgtt tcctagttat tattaataat actgctgata
    65941 ttatagctcc aagtactgcc gcaaagaacc atattgatgc tataataaat cctgacatac
    66001 ttccctctaa aagcgccaat gagaatatcc ccgctccagg cacttgaaga cctatattga
    66061 agaatgctac tatagaccca gttatggctg aaccagctac caatgatggt ataacacgga
    66121 ttgggtcctc tatcataaat ggtattgcac cttcagttat tccagccaat cctaatatcc
    66181 aagtttgctt tcctatttcc ttttctgatt ctgaaaataa atctctgcct aaaacagtag
    66241 ctattgtaac tccaaaagct gaaaccatct taactgatgc aaatattgca taaggtataa
    66301 aatttccact tgctattgct cctattgcaa atgtataggc tgctttattt attggtccac
    66361 ctaagtcaaa tgaaaccata gctcctatta ttgcacctag tagtattgca tttactccag
    66421 tcatcccatt taaccaattt ataagaccat tgttaagtgc tgctacaggc tttcctacta
    66481 caaataacat caataaacct actaccaaag aaccaactac tggatatacc caaaaactta
    66541 cgaatccagc taatgtgcct ttggctggta tattcttctt taaaaatttt actatataac
    66601 cagcaagtaa acctcctaac atacctccaa gaaatccact acctattaaa tcagctgcta
    66661 gacctgctgc aaatcctggt ccaagacctg gtttttcagc tagtgagtaa gacatatatg
    66721 ctgataatac tggaaccatc aatgtaccta acatacctcc agaaagcttt cttaattgcc
    66781 ataaccaaga accttcttga ttgtatagtt cttgtagacc aaatgcttga gatgctaata
    66841 ctgcaaatgc aagtatcata cctcctgcca caataagtgg tattatatga gatactcctg
    66901 taagtattgc tgattttaca tcttttttcc atgatgattt ttcacaatat gatatatcag
    66961 atgatttttc tatataatca cctttacctt gtttttgtgc tacttctaaa gcttcgtata
    67021 ttatttcttt tgctcttttt agtggagctg ctactgacgt ttttatgttt ggcaaatgtt
    67081 caaatctttc tgtattttta ggtgctacat ctgttgcata tattattgca tctgcccttt
    67141 ttattatatc tggtgtatga gggtccacca taccattagc tccttgcttt tctacataca
    67201 catccacacc gatttcttta ccagctttaa ttaatgcttc tgctgacata tatgtatgtg
    67261 ctatacctgc agggcatgct gttattgcta atataatttt ttttgattca ttttgaatcc
    67321 taatctcttc ttttatttgt tctttctttt cttttatatc taagttatta aataactctt
    67381 tcttagtttt tgaatttaac aacatattca tataatcttc atttgacagt ctagtaacta
    67441 actcagaaag tatttgtatg tgtgtatttc caccttcatt ttctggtact gctattaaaa
    67501 atattatctc tactttatta tttgggtcta cgctttccca attttctatt ggtgtctcta
    67561 aggtcatagc tgcaaatgca gcttctttaa ctgacttaga ttttccatga ggaattgcaa
    67621 gccctctttc aaaacctgtt ggagataaag tttctctgta cattacagct tctaaatatt
    67681 cctcataaga tgttaacttg ccttcatcat atagctttct tgctaagaac tttattgcgt
    67741 ctttctttgt ttttattttt tgttttaaaa aaacaaggtt ttcatttgtg attttcttaa
    67801 attccaaaat tacgccctcc ttaaatcatt taatgctatg aatatagcat aaaataaatt
    67861 atgaaaatgt ttttttgaaa ttatacacac aatttcttct taaaaaataa agatttgtgt
    67921 atttatacac aaatctctat cttaaccagt attgctctat tattgctctc ataatcatca
    67981 taattggaac cttatctgat atattgtacc catttacttg tttaattgtt gaatagcaat
    68041 ataaacttat atctgcaatt tgttgcaatt gattttcaca tatatgtgtt agagctacta
    68101 ccttacaacc cttattaact gctgtctttg ctacttctat aacttctttc gtttctccac
    68161 ttaaactaag tgcaaaaaac atatcttgtt cacctaattt tcctatatca tgaagtactt
    68221 catgtctttg actatagtaa gttatattat catgcccacc tctaatttct tttactaata
    68281 tctcacataa aggaatgttt tgacctattc cataaactat aatactccta gatttttgaa
    68341 ttatatctgc tactttattt attttttcat aatctattag ctctaatgtc ttttttatat
    68401 ctgattcaaa accatttttt ggctctttat cctcattttt taactcttct tttaaattat
    68461 tttttagttg agagaaacca tcatactcca tttttttaca tagcctaact atggtatttg
    68521 ggacagtaaa aaatttatct gctaaagatt gtattgataa ttttactatt tcttctttgt
    68581 tttttctcat atattcaatt atcatgtctt ctgtatctgt aaatttatac tcatattttt
    68641 ttgctctttc ataaaattcc atagtttctc ctccatctat tttattattc ataagtaaaa
    68701 ttcaaaaata ttagctaaaa ttttcgttaa tataattata atttaatatt tttaatttat
    68761 taatgcatac tactcttttt attatacata aaaaatgtgt acttcctata ttgatagaga
    68821 tgattcaagt ttttattttg atacatctct atcaatattt ttttagaaaa tacacatttt
    68881 tttcaaatac ttatttttaa ttaaaacttt aggtaatcta ttctttatat ataattatta
    68941 gacttgaaaa tatctttaaa atcaaccaat tcaatattat ttctttttaa ccacatttta
    69001 acttccttat cacatagcat tgcatgttca tatactctct cttgaataag agaagatgat
    69061 tttataagac tataatctat aaatcctgga tgagtaacca tcaatgttat atctttatct
    69121 aaatttatat atttttcttc aaataattta acaaaagatt tatttaactt gtaaaaatca
    69181 ttctgaggat atttacttgg catgctaata catgaatcca aataataggg acaacttggt
    69241 ataccgtatt cttttgcagc atcacacatt gctgatattg atacatcttc ttctatacca
    69301 tgtatatcaa tatactcagg caatttactc atatacaact tgtaagtttc aatttgagca
    69361 caaacttctt catatacttc ttcataatta aaaacctctt tacctgtcag tagttgcgtt
    69421 cttcttattt tgctagaaac aaattttcca ccttcatcta acaaattctt tatcttaata
    69481 tgttctttgc aacaaggttc tcctattact aaattaacat gtaaaccaaa acatacatca
    69541 tcatttttta ccatttctat agcttgtctt gaaaaaggca tattcaccat gattccagca
    69601 cttgtaacaa taccgttctt ataagaagat attatcccta gtgtaacacc ttctgaatat
    69661 cctatatcat ctgccctaac tactagtttc ttcattttat gcgtctgcct gctttctcaa
    69721 ctcatcaagt tgcatttcca tctcatcctt tactttaaca acatccgttc ctatgatgat
    69781 ttgaactgat gtattactca atttaattac ccctttggct cctgtttttt taatattatc
    69841 atcattcaaa atagtagcat ccttcacttc taaacgtaat ctcgtcatac aattattaag
    69901 agtcactata ttttcataac caccacaatt tttaattatc tgtttagcca tatatgaaaa
    69961 attaccatga gaaagtttta aattcttttc tttttcacta actttatcac ctatctctat
    70021 ctcaacttca cgtcctggtg tttgcacatt atcttttatt attatatatt taaatgttac
    70081 ataatataat acaaagaata caactcctac aggtataact aaccacgctt tatctccata
    70141 actaaaactt aagacatagt caattatact tgctccatta aatgaaccca agcgaacacc
    70201 cagtaaatat agtacaactc cacctagacc agaataaaaa gaatgaatta tatataactt
    70261 tggagatgca aataaaaacg aaaattctat tggttcagtt actgttgcca taaaagaagt
    70321 caatgctcca gcggtcattg caccttttac ttcttgcttc tttttatctt gtgctgtttt
    70381 atatatagca taagaaatag caggtattga aaacatcata attatgtaaa atcctgtcca
    70441 gaagaatcct gcatttgggt ctcctgccat aaatctagga atttctcctc ttataacttc
    70501 tcctgttgat gttgtatatt cacccatttc aaataatatg taagcattta aaacttgatg
    70561 taacccagtt ggtattagtg cacggttaca gaataaaaac aagaatattc ctattgcacc
    70621 agctcctccc aaccaaaaac caaattgatt cattgcagct tgtggatata tccataataa
    70681 actaaatata tatgataaaa ttaaagcaac cactggtgat agtgtaatta cacatttttc
    70741 tcctgcaaag aagcttaaaa atgctggaac tttaacttta tatgttttat tgtaagtcca
    70801 tgctatacaa gctccaacaa ttatcccacc aaatacacct gcatttaatg tatcattcaa
    70861 taactctaaa tttgacttaa atatcatata tgcaactacg gctgcaacca ttacacttgt
    70921 cttgtcttta gactttgagt aggcactagc tgctcctaat aaaaataagt agtccacatt
    70981 tgaaaatact atattagata tattagatat agctggcaca ttgagcatat ttggaccaaa
    71041 taataatcct aatatacctg ctgctggcat tacagctatt ggcactagca tagtctttcc
    71101 taaaagtgac agttgttgca tcattttgtt taagaacctc ttcatatcca atcccctttc
    71161 tatttcggtt taattttttg tgaaaacgat ttattcacat tttatatttt aaatattata
    71221 tttgtttaaa caaattgtca atatttttta ttcattttat ttttatcatt tagtttaaca
    71281 tataaatcct tttaagtgta ttgctatatc tagtctattt ttttaattca ttttttttat
    71341 tttaaaaata tgtttaacca tgtatttgaa acaacccaca aaataattct attttgtcct
    71401 ttttatggtt gatatgattc tattttcact atacatgtct aaacacattt gatataattt
    71461 gttcatatca gttcaataat attactaaag acctttaagg agggataggg gtatatggct
    71521 aaaaataaat tttcagagat atatgaagta ttgaaagagg aaatacttga tggtaaatat
    71581 acaagtaata tgatgctgcc tactgaactt caacttattg aaaggttttc atgtagcaga
    71641 aacactgtac gtagagcaat ttctcaatta aacacagaag gatatgttca aagtataaaa
    71701 ggcaagggtg ttgtagtgtt agaaaatagt tgttctaatg atttttttct aaatatgcac
    71761 aatttcaaag gtgtagaatc gattgtagaa gataaaaagg ttaatactgc tactagtgtt
    71821 ctccacttca gcaaaatctt aattgataat aagttatcta aaaagacagg ttttaaagtt
    71881 ggtagtgaag tatattacct tcacagacta agatatattg ataacatacc taaaattctc
    71941 gacattaact attttctatg tagtatagtt aaagaccttg atgtttctat agcacaaggc
    72001 tctatttata aatatataga agagtgtcta ggtacaaaaa ttgtttcatc cagaaagata
    72061 tttaaaattg aaaaagctac agagcttgag ttaaaaacgc tacctctaaa tgattataat
    72121 tgtgttggtg ttattaaaaa tagtgtatat actgatgatg gaaagctttt tgaatatact
    72181 gaatcaaagc atacacctga aacatttgta ttcatggatg ttactcaaag atattaaaaa
    72241 aattatgttt aattaaacat aattttttta cgtttagaca ctttatccca tactaacctc
    72301 actattctat atacaattat gtgtttatac aaataattat ttattgtata ttttagcttt
    72361 aatattagtt taatgcttga caatttgttt aaacatatta taattaactt ataaattaca
    72421 ggaggtatca attatgaaaa attggtggaa aaaagcaact gtctatcaaa tatatccaaa
    72481 aagtttcaaa gatagcaaca atgatggtat aggtgatata aatggtatta tagaaaaatt
    72541 agattatctg tattatttag gtgttgattt attatggttg actcctatgt acgtttctcc
    72601 tcaaagagat aatggatatg atatagaaga ttattataat atagacccaa aatatgggac
    72661 aatgagtgac tttgaaaaac tcttaaaaga agctcataaa agagacataa aaataatgat
    72721 ggatatggtc ctaaaccata catctactga acataaatgg tttaaagaat ctaaaaaaag
    72781 caaagacaat ccatatcgtg attattattt ctggaaagat gctaaacctg atggttctgt
    72841 tcctaataac tggatatcca gatttagtgg aactgcttgg aaatatgatg aaaccactaa
    72901 ccaatattat ttacatttat ttgaagaaac tcaagctgat ttaaattggg aaaatgaaaa
    72961 ggttcgtgaa gaatgttaca aaatactaga attttgggct gataaaggta ttgatggttt
    73021 tcgtttagat gtagtcaacc tactctccaa aacacctgga ttacctgatg accctataac
    73081 aggaccaaaa ggagatggaa gaactcacta cgctgatggt cctcgtatac acgaatattt
    73141 acataatatg aatcaaaaag ttttcaaacc taaaaatata gttactgtag gtgaaatgtc
    73201 atctactaca cctgaagagt gtatcaacta tactagagaa aatcgagaag aactatctat
    73261 ggtttttagc ttccatcata tgaaaacaga ttataaagga ggcgcaaaat ggactaatga
    73321 aatgttctct ctggataaat taaaaaaagc acaatctgac tttcaatata aaatgtatga
    73381 aggaaaagga tggaatgctc tattttactc taatcacgac caacctagag ctttatctag
    73441 atttggagat gatagatttt ttcgtcaaga aagtgctaag atgttagcca taacactatt
    73501 tggtctacaa ggtactacat acatatatca aggtgaagaa ataggtatga caaatgccta
    73561 ctttactaaa atagatgaat atgatgatgc tgaaagtaag aatgcatact atcatatgat
    73621 taaatctggt attgatgaaa aggaggcatt gcttatactt caacaaaaat ccagagataa
    73681 tgcccgtact cctatgcaat gggataatac tatttataag gggttttcta atcataaacc
    73741 gtggttaaaa gttaataatg acaatattag tgtagaaaat gagcttaatg attctcgttc
    73801 agtattttat acttatcaaa gattaatcaa atatcgtaaa caatatgata tttttacaga
    73861 aggtacttat agattgttag atgaaaatca taaaaatcta tttgtttatg aaagagagta
    73921 taaaaaccaa aatcttcttg ttataagtaa tttcactcat gataatgtag tatataaatt
    73981 acctgaaact tatttgaata aattaaacta cacaatactt gaaaccaatt acactagaga
    74041 tataattgaa aataaaatgg aaataaaacc ttacgaaagt ataatgatat attataaata
    74101 aagttattta tgtaaaaata ggtataacac cctggtgtta taccaatttt actaaattca
    74161 aagtaatgtt tatagaatat ctatagatta caataattat ttgacttcta catcattata
    74221 tttctttgaa tatactttag tcatatagaa atatatagga actacaatta tcatcccacc
    74281 taatccccaa actatcttca taggttcatc aatacctgct tttatcagta ataatatact
    74341 tataataact gcaaatattg gtataattgc tcctccaggt attctaaaat ttacatcttt
    74401 accagcatac ttctttctca atattagtac agctaaacat gtaggaatat attgaataaa
    74461 tctagataca acacttattt gagataatgt tgtgaatgaa cccgaccatg ctattagtaa
    74521 agttcctatg acagatacta taattgctat ataaggagct ccatttttat tagtttgtct
    74581 tatagactta ggcattaatc cttgttcaac caaagcagca gcagaccttg gtgtaaatat
    74641 ggatgatgca atatttatac ctccaacaga tactatagtt cctattgtaa ttatataccc
    74701 acctatagga cctaacatct taatggcagc atctgcaaca ggagtagctg accctgctaa
    74761 gccattaccc aacaccccta tacttattcc cagtataagc atatatatta ctgatactac
    74821 aaacattacc attaccaatg ctttaggtac atttttctta gggttctcca tatcttttgc
    74881 tgcaacagct aaagattcaa atcctgtaaa agcataaaat aaagttatag atactgctac
    74941 aaaagctgat gacgcacttt gacctttttg tattattaca aatggggtaa aattagaacc
    75001 ctttataaag aataatccta cagctataaa taaaactatt ggtaataatt ttcctatagt
    75061 catgatatta tttaagtgct tagattgttt cattcccata aaatttataa tcccaagccc
    75121 tacaactaat ataccaatta ttatattttt aataagtggt tctgctgctt gtggccatac
    75181 agatgatagt gttacagcaa agaaatttgc catagtagcc caagcaatca tactaactat
    75241 ccacttcata aatccaactt caaatccaac aaaatctcca aatgcctctt ttgcataaag
    75301 atagggccct ccatcagtat caaaccaact acctgcttca gcaaaacata aagcaataga
    75361 aacagctaaa agcatacaaa aaactaatac taatatactt gctggaccta tatctgtata
    75421 agcatcacca ggtaacccga atatacctga ccctattatt gcattgattc ctaatagtac
    75481 aatactccaa aaacctaact taatgccttt ttccattgtt attcccccca aagccaactt
    75541 aatatatttg tattttttat ttagatgctt ctttaactat tgccataaat atttttttca
    75601 tattatcata atctctagtc atcatttctg gatgccattg tatccctatt acaaactcac
    75661 ttccttcctt ttctatagct tcaattaaac cgtctttaga tgtagctgaa acaatatatc
    75721 ccggtgctac tttgttgaca actaagtgat gaaaactatt aactaaaact tctttttctc
    75781 ctagtatttc atataatttt gtcccctcct ttatctgtac tgtatgtgta ggtacattag
    75841 atagatgttg ctgattgtgt ttaatataag caccttcaat taaagataaa tcttgataca
    75901 aactacctcc ttcagttaca tttataattt gttctcctct acatatacct aaaactggtt
    75961 ttttcatatc taaagcatgt tttaataatt tcatatcaaa actatctctc tttggtgata
    76021 ttgcccccaa cttattatga ggttcttctt tccatatgag tggatttaca tcttgtcccc
    76081 cagatagtat aagcgcatct atattagata cctgctcctt tataatctca tcatcatata
    76141 caatcggtac aatatatggt atagctttac acataactac tgattgtata taatcattat
    76201 ttacataagc cctttcatag ccaggaaaca ttcctccttc atcaattagt aaattacctg
    76261 atattcctat tattggatat ttctttttag ccaatttctt caccccttaa cttatttgtg
    76321 aacaataaaa aatgctactt ctcttaaaga gcaagtagca taccaagatt ttatttattt
    76381 gaacattata atttatttta gaaatacttt ttttgaatac gagtaatata aataacttta
    76441 tttacttata ttttatttta atcctgttta gtttgacttt tttaaattgt tttaagtaca
    76501 actaataggt aaaataggca tttagatttt cctttttatc aacctattaa atactgttta
    76561 atatattttt tccccttcta tttaattcac ttccctttct accagattca catattatca
    76621 aatccagctc ttttaacata ttaagtattc ctcttacctc accttctgtt atattgtagc
    76681 ctaattcatt tattgaatta acaataccat ttctacctat atttttatta agattattgg
    76741 cattttttaa acactccatt actaacttta ctttctctat agatgttcta tcctttaata
    76801 tgcttatttc tttactaaaa tcttcagtta tatttaataa gttatgaggt aaatcattta
    76861 ttaaaataac atcctcagaa ctcataatgt taatatacat agcagtattt tttaattctc
    76921 ttatattacc tggccattca tatgcattaa taatgtcttg aacatcttga ctaattgctc
    76981 tcttcctttt cataaaatgc tttaacataa cttctatatc ttcttttcgc tctcttaaag
    77041 gtggtatatt tatgggcaat acatttatcc tatagtataa atctgctcta aatctatctc
    77101 cttttatcat ttctaataaa tttttatttg tagccgcaat tactctaaca tctatatcta
    77161 ttacattttc tcctccaacc ctcattactt gattctcttg taatactcta agtaatttgc
    77221 tttgtaagta tataggcatg tctcctattt catccaaaaa tatagttcca ttgttagcct
    77281 gttcaaataa tcctttttta cctcctttta aagctcctgt aaaagcacct tcttcatatc
    77341 caaaaagttc actttcaagt aaattttctg gcatagctgc acagtttatt gctataaatg
    77401 gctgactatg tcttggtgat gcattatgaa tagactgagc catgagttct tttcctgttc
    77461 cactttctcc cgttataaga attgtataat cagattcagc tattttcata cctaatttct
    77521 tagttctttc catcttcgtt gaaactgttt ttatatcatc aaaagtatat ctagcaactt
    77581 gtcccttttc tctaagcttc tttgataggt tttgctccaa ttttcttatg taagttattt
    77641 cttgaataca aaaataatat ccagtaaccc ttccaaaact ctctatatta tacttattta
    77701 cgtttaagta cttattatta aattttataa cttcatcatg tgccttactc aaactaaaaa
    77761 tctttttaat attctcattc tctaattcat ctatattttt ccctataata ttactttgaa
    77821 tatctagtat atcccttaaa ctattattac aaataattat gtttccctta tctgatacca
    77881 ttgccatacc taagtttgat aaatttatta tggaatttag ttcatctgct tttatagtaa
    77941 gttctttgta tttagtattt attcctgaat ataaactaat tatttcatct gtatacttaa
    78001 ttagcctctc agtaatttct ttatcatcca gtttgagttt tgctattatt tgaataaacg
    78061 ttgaactatc aatataccta tggcctaaat caataacttc ttctatatat tttggaacta
    78121 aacttgactc tcctggcgtt atagctatct taatatttct atattcttca ttgggattgt
    78181 atggtataaa attcaaatga tttattccta tattgtataa attagatatt gtttccaata
    78241 cagtatgctt attatcgttt actactaata catctattcc ttctggcaat gaaaataact
    78301 tatatatatc cttttgcttt atgctcctat ttatagttat tatctttgag acatcttcca
    78361 catatttttt tatttttaat actctatcat ctatcattac caatattatg tcatctttta
    78421 ttaattcctt ctctgttatt ttatttaaat aataattttt tatcattact ttatctttaa
    78481 agatcatttc tagattttta tttaagaaac attctaattt agacaaccca tcagttacta
    78541 ctgctattgt tttcatttga ttactccttt taaaatatac tctactcttt tataatatac
    78601 atttgatttt cactttaata acacaaaaaa ttgtacattt agtatactaa catattcctt
    78661 tattagtttt atgtccataa atatcatagt tgcaatatct atcatatttc ttaaacttct
    78721 ataaagcaaa aattgtgcca aattaataat tttcttaatt ttattctaaa gttcctcaat
    78781 agtatttaca gacttagcac ttatagctta taagtcttta tattattaat ctatttttat
    78841 aggttaattg tacaaatcat atatcacttt tacctattaa atgcattata aaaaattgta
    78901 tttataaaca ctatttacta ctcttctaag tacaaacagt atctacatac tataaccttt
    78961 caccattaga ttctattact tgtttatacc agtcaaaact ctttttctta atcctagaca
    79021 agtctccact tccatcatca tacttatcca cgtatataaa cccatatctc ttggccatct
    79081 caccagtaga tgcacttact aaatctatac atccccatgg agtatatcca aataaatcaa
    79141 cgccatcttc tacagcttcc ttcatttgct ctatatgtgc ttttaaatac tctatacgat
    79201 agtcatcatt tatcactcca ttagattctt ttttatcata agctcctaaa ccattttcaa
    79261 ctaccatcat aggtattcta tatctatcat aaatttcatt tagtgcatat ctaagccctt
    79321 cagggtctat ttgccatccc cattcactag acttaagata tggatttttc actccaccta
    79381 atatgttgcc acttgtatta tcttctttag aatcactact tacacatgta gacatataat
    79441 aactaaatgt ataaaaatct acacaacctt cttttaaaat ttctaaatct cctttttcca
    79501 tttttatttc aatattattt tctccaaaat atctattcat ataagttgga tattcgccac
    79561 gcacttgtac atctccacag aaataattca ttactctact atctctttga gttttaactg
    79621 catcatctgg attacaagta taaggataca ttgttgcaaa tatttgcata catccaactt
    79681 gataatttga atctatttca tgagctaact taacagcctt agcacttgct acaaattgat
    79741 gatgtaaccc ttgaaaacga agttgaggta tatctacttg gtttataaaa tctgtagtcc
    79801 cttcatttaa tattccttgt gataagtagc ctcccatagg cattgtagct gaatttattt
    79861 cattaaatgt cagccaatat tttacttttc ctttatatct tttaaatatt gtttcacagt
    79921 aattcatata caagtctatt acatctcttg aaacccatcc attgtatttc tctgttattg
    79981 caaatggtat ttcatagtga gatattgtta ttaatggttc tatattatat tttaaacatt
    80041 catctatcac attttcataa aatttaagtc ctgcttcatt tggttctttc tccattccag
    80101 ttggaaatat tctagtccat gctattgaaa atctaaatac cttaaatccc atttctgcaa
    80161 ataaagctat atcttctttg tatctgtgat aaaaatctat tgcttcatga cttggataaa
    80221 atgttccttt ttctataact ctcgttattc ttttacttac tttttgagaa cctccagtac
    80281 acatatctga acaagaagga cctttcccat ctaaattcca tgctccttca cattgatttg
    80341 ctgctgttgc tccaccccat aaaaaatctt ttctaagtgc cataattcta cctccaataa
    80401 tttatttata gtaactttat tttaaaataa aaatacatat atataattct taattaatag
    80461 aactctcttt tacgctaaaa cagttatcaa tttctgacta ttatttacat gcttttgtgt
    80521 attttctaca atatccacat aatcagaata attagtaaca actactggtg tttctaagca
    80581 atatccttct tttgaaatac tttctatgtc aaaagttatt aatgtctgac cttttttaat
    80641 cttatcccct tgattaacaa aagatttgaa atatttacct tccaactgaa tagtatttaa
    80701 ccctatatgt atcaatagtt cacaaccatt atcagatata attcctattg catgttttgt
    80761 tggaaataaa gtcattacag tcccatcaaa tggtgccact acttttcctt ctttaggtgt
    80821 tattgctaca ccttttccca atatacctgt tgaaaacgct gcatcttgta tctgctccaa
    80881 agcctttact tcacctttta ttgggctata tactacttct cttttgtttt tttctataac
    80941 gccttgccca ttatcatctt tagaaatttc tactatagca tcatctttcc aaaaaaataa
    81001 tgttaaaaca aatcctacta caatagctac tattattgct attatagttg cataaacacc
    81061 tttcatatct ccagttgttg gatttatata attaggtata ccaaatattc caagtccacc
    81121 cattacataa ctttttacat tcattatccc cattacagct cctgccacag caccacctac
    81181 acaactatat atgaatggtg tttttcttgg taaagttatt ccatatattg caggctctgt
    81241 tacaccacat atccctgaaa taactgcagg tatacacagc tcttttatct tcttatcttt
    81301 taatttaaag tacattgctg ctactactgc tgtttgtgca aaagatggta caaatactcc
    81361 cactaatatt gtgtcaaacc ccatagtcat aaggtttgac atagctattg gtactaatcc
    81421 ccaatgtaga ccaaatatta caagcacttg ccacaataaa ccagttaatg caccacataa
    81481 aattggtgaa aagttaaata aagctaaaaa tccatttcca actatattag aagcataggt
    81541 agctataggc cctataacca taaatcccaa tggtaaagaa actaataaaa ctgccattgg
    81601 tacaaagaaa ttctttacta catctggtat tattttagca aacactttct ccaacttagc
    81661 tgctaataat actattaaaa ttactggtac tactgttgaa gtgtagttca ttgctattac
    81721 tggtaatcct aagaaagtta tatatactgg tgattcaaat attgttccag taaatagatt
    81781 gtataaaggt tgacctgtag atgctagagt atctaattga atacctgaat agcataaaac
    81841 tgcacctata agcattccaa taaatggttt taatttgaat ttcttagcag ctgtatatcc
    81901 aagaattatt ggcatatact ggaacattgc atctccaatt gcatttaaca taatatatgc
    81961 accatcagtt tctccataca aacccaatgc tgtaaatact gcattaaatc cttttatcat
    82021 accagcagca cacagaactc ctaatattgg ttgaaaaact cctgatatta tgtctataaa
    82081 cttattaagt aatccttttg gcgcatctga gtctgaatta tctattgtat ctcctcctaa
    82141 tccagccaaa tcgcacacaa cttcataaac atctggaaca tgattaccaa taactacttg
    82201 gtattgacct gcacttttca ttacagtaac tataccatcc atttttttta gcacatcatc
    82261 atttgctatt gactcatctt ttaatttaaa acgtagcctc gttatacagt gagataaact
    82321 gctaatatta tcctttcctc ctacattcgc aatgatttct tttgatagtt gttcatactt
    82381 tctcattttt tctcctccat tttctttttg aaatatgaag gtttggccaa cttaatgtca
    82441 ccacccaata tatataaacc taattattag gatttatatc cgacttaata cttttactta
    82501 ccactctttc aacgtgaata gttaagtata atttttcctc atctgttaaa tcgtagttgt
    82561 attttttatg tataaattca tccaactttt ctatgaattt ataagcattt ttatatttaa
    82621 cttttattac atttaataaa tcatcttcat tattttcatg taaattatta ctaacaattc
    82681 gttctgcaaa atactttaag tgagtaataa atctatgata ataaactgaa tcttcatcaa
    82741 atactattct gtaatggtat ttaaccatat ttgaaatttc ttgtattatt tgtgtaatct
    82801 catatatagt ttttatactt tgatccattt gtgcattaac tatatgcagt gctataaatc
    82861 cagcttcatc ttctgatagt ctaatttcaa attttttttc tatataatcc aatgcctcta
    82921 accctatttt aaattcactc ttataaaatc tttttatatc ccaaagtaat acatttttta
    82981 cacttactcc ttcacgagct ctttctattg cagtatacat atggtctgtt aaagaaatat
    83041 aaatactatc atttaatctt ttccctagtt tttctttagc atataaaatt atttcatctg
    83101 ataattccat atatcttata ggaatatctg ctattagttc tttaaattta tcagatatat
    83161 ttgggtctga aagtttgaat atcttatcaa ttttatcctt tgatatatgc tctcctgtac
    83221 gttttttata agctaaacct ctccccataa ctactatttc cttatgattt tcatcagttg
    83281 taataattac attattattg agtatttttt caataatcat tgtgatgccc cctttattag
    83341 cattaagtta aaataaatct tttttaatta tttagaatat ttaaaatgta atttattaca
    83401 taaaaaaaaa cctatttatt acacattaaa tagactccca tgagtcctga gtaataaata
    83461 ggtttagctt gtatttaaac aatcactatc cgtttgtatt ttattttaat tattatttat
    83521 tatatgttag caaatttatt ttttagtgtc aactttttct caatatttta attttaaata
    83581 aattatataa attgaatctt caaagtacta tttttatcaa taaacaaaat aaaaaaggta
    83641 ttactttctt taagtaatac ccatttattt ctaatttaag tggtttttct taatctcatc
    83701 aagtagtcca tcttctaaat aaatttctaa tgcacatcct accattgcct ttactgcttt
    83761 gtgaagttta tcataagctt cctcagaatt tgcataattt agaaattctt tttcatgaac
    83821 atataccatt ggacttatat ctaaggctat ttctgtatac atagtagggc aaacttgact
    83881 tacattacct atatctgtag aacctactgg accatcttta ccttctaata tatctgttat
    83941 acctgcctca atcaaattat tctttgttat cttttgaagt actttgttat ttattatgtt
    84001 gtcaaaagaa ttttcaaagt atctataaga aagcttagct cctgtcatta actctgcacc
    84061 ttttgcacag tttataactt ttttagttac ttcatctaaa taacttcttt cagcagctct
    84121 tacgaaaaac ttacaagctg ctttttctgg aactatattt ggagcctctc ctccatttga
    84181 aactatacca tgtattctaa catctgattt tacatgttgt cttagtgcat ttatcccagc
    84241 aaaagtaagt tgtactgcat ctagtgcatt gactcccata tgagggtgac tagctgcatg
    84301 tgctgatacc ccttcaaaac taaactctaa tgaatctatc gccaaagcct tacagtttat
    84361 attattaaaa gcttctatat gcatttgata acttacatca acatcatcaa aagctcctgc
    84421 cttaactaaa tcacattttc ctcctgttgt ttcttcagct ggtgttccta ttagtacaat
    84481 ttttccttta aaattttctt ttaacttact taatactata caagctccta gtgtagatgc
    84541 tgcaatccag ttatgtccac aagcatgagc tggttcttta ttttctccat atccaggaag
    84601 tgcatcatac tcagctaaaa atgctatggt aggtccatca ttatctccta attcagctct
    84661 aaaagcagtc tccatattac aatatggata aactgtatca aatccatatt ccttcatttt
    84721 ttctactaag tattttgatg atatgtattc ttcttcccct aattcaggat tgttaaatat
    84781 aaaattacaa acttcttcaa tttcttttcc aagttcattc tctatctcat aagctctctt
    84841 ctttatactc tctatcataa tttacctcct actagaatcc tagatataat cctattgtca
    84901 aaaatgccat tacaagaatt gttaatacta ccattaaagg aattacgaat ctaacccact
    84961 ttgaccaagg aatattggct actgctagtg ctcccattaa aacacctgat gtaggtgtta
    85021 tcaagttagt tacacctata ccaaattgat aagctgtaac tatcatttgt cttgatacat
    85081 ctactaagtc gccaagtggt gcaagtacag gtattgtaag tgatgcaagc cctgatgctg
    85141 atggtattaa aaatgctatt aatccttcta ttaagaaagt taaatttata aatatagttt
    85201 ttggtaatcc atttaataaa tttgctgcag aatttaaaat tgtatctatt ataaatccat
    85261 tttctgctat tattacaatt ccacgtgcaa atgctataca caatcctgct gtcattaaat
    85321 ctcctgctcc acttataaat gaattaacta tatcatcttg tttaagacct gatgctatac
    85381 ctgatattat acctatagct gtaaatatca ttgcaatttc agttatatac catcccaact
    85441 ttaaaactcc atatatcata atcgccatac ctattgtgaa aattgctatt accatggctt
    85501 ctctttttgt aaattccttt atatttgtat cactattaac cattgattct tgatttagtg
    85561 atatatcgtg tactaaagat tttttagggt cttttttaac tttattggca tacatcataa
    85621 caaatcctat agatatagcc atatatatta taaacataac aactctaaac tctattccag
    85681 aacctggtgc tatttgtgat aatgcttgtg ctattcctac agagaaagga ttcgtagtag
    85741 ctgctccaaa tccagctgtt gctcctataa atactgtggc cactgctgtc aatgaatcat
    85801 atcccatact ggtcataagt ggaataaata tcatataaaa aggtagtgtc tcttcactca
    85861 ttccaaacgt cgtcccacct agtccaaata gaatcattga aatcggtatt attaaaaatt
    85921 gaaacttctt cattttattt acagtatgag ctataacagc ttctatagct cctgttttat
    85981 taactatccc aaaagctcct ccaactatta aaacaaatcc aactacttca gcagcatcta
    86041 taaacccgtt tataggtgct gtaaatacat cagtaattcc ttgtggattt gatggtgctt
    86101 tttcataagt tccagctaca acaactgacc ttccgtctat atctactctt tcaaaatttc
    86161 cacttggcac tatccaagta agaattgcca ttaacactat tagcaaaaat attattgtaa
    86221 gtgtctgtgg catagtaaac tttttctttt ttaaactgct catttttaat ctccccactt
    86281 tttaaattaa atattttatt attgcatccc tttatcctat tttgtataga tgtaaaaaag
    86341 ctcaacatgg atacatgttg agctaaatgt gctaaataca acatacctgc atcttccctt
    86401 tatcttgttt aagatagctc tccatcaaaa ttcgggataa ttttgatgac agtactgtac
    86461 ctattaaata cagtcccagc actagcttcg gacactagca cttcggcact tactcctttt
    86521 atattgcctc attggtttcc aacctcttca atattaatct tagtaaatgc aacctctacc
    86581 tcaatctgtt tgttagatga ggtaattctt attaattttt attaattcaa agtaattgta
    86641 gcataatatg tcgagattgt aaatattttc agtataataa ttcttacttt atgatttcat
    86701 tccatttttc acaaataatt ttttctccat ataatttaaa tactgtagta tattttaaat
    86761 acacacaaac tttccacaaa ttttaaatta ttataatacc tttataataa aaaataaaag
    86821 ctatgtaaac ttatcaattt acacagcttt atatacatta atctactcca agtacagctt
    86881 taagctttga tgctattgta ataactcgtg gaccaaatat aacttgaact gagtttttct
    86941 ttttaacaac tccacttgca cccaattcat ttacccagaa gccatcttca tagaatccat
    87001 caattgaatt tagctctacc ctaagtctag ttgcacagtt tgtaacattt tttatattat
    87061 tacttcctcc taaaccttct attatagaat gtacaagctt tgtatcttta tcatctactt
    87121 cctcttctac tgcattgttg tatgctgttt taccagcatc tacagattgt ctttctctat
    87181 attctttctt actataaagc ttaacttctt ctgaacttct tcctggtgtt tttatatcaa
    87241 acttcttgat tgcccatgta aatattatat aagtaactat aaaaaatatt ggtatcaaaa
    87301 ataataatgg taacgcatcc actttttgtg gttgtaataa attaggaaac atatttctaa
    87361 atgattctcc cattatagaa acattaaaca tttctgtaaa tacatacgtc aatcctgcca
    87421 gtggtacata tgctacaaaa tacaataatg gtgcaacaaa taggaatgta tactctattg
    87481 gttccgttac ccctaccaac atggctgtta ctattgctgg tatcaatata cttattgctt
    87541 ttttcttatt agcattatca gccaacttat acatagctaa agctgctgct ggtaatattg
    87601 caaaatgtat taataaacga cctgttgtga agttacgagt tatataagat agtgtatctg
    87661 ggtctcccat ttgagctaat cttatattat taacaccctc gtaaattgct ccacctactt
    87721 ccattgttcc acctactctt gtatattcta tagggaatgc aattaagtga tgtataccaa
    87781 atggtaataa tgctttatcc attgctccaa aagtaaatgt tcctaataat ccactagaac
    87841 ctatccaatt accaagttta gataatgcca accctactgg tggccatata aagtacattg
    87901 ctgtacccaa tactattgat gctataaaca tcataatcat tgaaaatctt ggacctgaga
    87961 aaaaagataa tgcactagga agttctatgt caacaaattt gttatgtact gcactagcta
    88021 caaatccagc tattatagct ccaaatatac tacaatcata tgaaaagatt cctaagaaag
    88081 aaccatataa agaacttcga ctatatgctt ctgcctctcc taatccagat gccataaacg
    88141 cttctgctgt aactgtatct gaatttatac catttgctgc taacaatgta cttataactg
    88201 tgtgcattcc tataaataaa acaattcctc ctaatgcacc ccatcctttt tcctttttag
    88261 ataatccaaa ggctatacct gtaacaaaga atattggtaa gtatctcatt accataaatc
    88321 ctaaatcgtt tattacttta aagaatacat ttataaatga cccttctttt attagtccgc
    88381 taagccctaa tgcagaaacg ttttccatat ttgcaaaagc tgaccctagt cctataaata
    88441 ctcctgctac aacaagtaat ataacaggta tcatcattgc tccagaaagt acttgtaatt
    88501 tatccttcat agtattattt cctccatttt tattgaaatg ccaggctata taatgcatat
    88561 atatatactt ctattgcttt gtataatgta tctatactta tattttcatt tgcctgatgt
    88621 gaatttggat tatccccctc tattgtgggt ccaaatgcaa ctccattttt taacactctt
    88681 gcataagatg cagctccttt tgtaaaaagt tcggcttctt ttccaaaacc ttgtttatat
    88741 gcatttgata atttatttat taattcacta tctggtttta catacagtaa ttttaaatcc
    88801 ttatatatat caactattaa attttctttt tttccaattt cattaattct attagttata
    88861 aactcccaac ttataccctt aggatatcta aagtctattt tcatattcaa ttcatttttc
    88921 tctaagaaga tactcattat acatattgta gaaactccca tatctacatc ttctttatat
    88981 atccctaatt tttttccatg attatcatct gtaaagtatg aatttaaaat atcccttatt
    89041 ataacgcctt tatcatttag ttttttaatt ttctctaaat cttttgctaa actaaatgca
    89101 cagttatatg acctgtgtgg atttctcgat aaagcccttt ctcctgtata tcttactaat
    89161 actttacctt cttctagttc ttctatctct gtataataag ctaatgattc tactaaatct
    89221 ttcttatcat tagttttaaa aacagcctca attttgtcac atacaaatcc atcttctttg
    89281 tttgacttta tatcaactaa attgtgattt ctaaatttat ctttatctat tttctttctt
    89341 agattgaagt ataaaatacc tttttctcca tttactattg ggaagtttcc atctggagaa
    89401 aatgcaaatt ttggctgttc attgacacta aagtaatgct ccatacattc ccaagtcgtc
    89461 tcttcagctc cacccactat caatctaatc tttctcttcg gcttttcatt aagttctctt
    89521 aagaaaagta atgcatataa aatccctatc aaaggtcctt tgttgtcatt aactcctcta
    89581 ccataaagat agttatcttt ttgacatact ttaaaaggtt tactcttcca aagttcttta
    89641 ttatatattg gcaccacatc tatatgatta agcaccccta ctacttcttc tccttctcca
    89701 tattctatat gaattgcata tccatcaaag tcttttacaa caaaatcttt gtcttttgct
    89761 atttgaataa gcttatcgaa ggcatttctt atttctatcc caaatggttg atttatatct
    89821 gttgtacttt catctctaat tgaaggtatt tcaactaaac ttctaatatc atttatgata
    89881 ttttcttgat tggattttaa ataatcaata attagttctt tgtttactat catcttaatt
    89941 atttatcacc cctttatatt aattttacaa agcatttcag ttcatatcta cattataaat
    90001 tttgaatatt attttttcaa tatttcaaat acttctctaa gttaccataa tgatacggta
    90061 aacaatcaac agattatgac aaaatcatac tatacctatt actaatattt taacttatct
    90121 attacgtctt ttttaatgta agtttattcc aaaaatacat aaaaaaagat gtagccttag
    90181 ctacaccttc ttatatctat tcaacttcca ttattatgct attaatatct acatttccag
    90241 gttctatcct atcttttact gttctcttaa cagaatcagc atcatccatt ataactacag
    90301 gagttattat atttaaatca tttgacgtta taaaatctaa atctacttcc attattaaat
    90361 ctttagcttt taccttatct cctgccttta ccttaacatc aaacggcttt ccttctagtg
    90421 acattgtctc taaacctaca tgtattaata tatttgtatt atcattactc ttaatcatta
    90481 ttgcatgctt tgtatcaaat acattgacta tttcaccatc aacaggagaa tataacttac
    90541 cttcacttgg tattattgct actccatctc ccatcatctt ttgggcaaaa actgcatctg
    90601 gaacatcttc taagttcact aaatttccct taaaagggct atatattttc tcaatcttat
    90661 tttctttttt cttaaatata ttaaacataa cacactctcc acattataaa attttatgat
    90721 aatatttttc ttaaagcttt tgctacacca tcatttacat tagtatcagt tacaaaatct
    90781 gccatagatt ttacttcatc tgtagcattt cccatagcaa taccaagacc tgcaaattta
    90841 atcatggata tatcattttc attatcacct atacaaataa cttctttgct atctatacct
    90901 aatatatcac aaaatttttt aactgcaata ccttttgaag tacctttact cataacttca
    90961 aagtttatct ttccagaact tactacttct aaatcttctt gttttttaaa ttcttccttt
    91021 gcttctctca aagaatctac gttttctgag aaaagtatac attttaaaat ttcattatca
    91081 gctttttcta ataaagtttc acaacttgca ttttctatta tttcaattct gtcttcttct
    91141 ttatttttac tatttattaa tctatatgga tgttcttcac ctatttcatt gttggatata
    91201 actattttac agcctttaaa atgtttgctt aaattatact tttcacctat tgtatagatt
    91261 ttctttagag cttctttgct caaaaccttc ttatactcat atcccagtaa tttaaaatat
    91321 gtcccattag ttgatataat atatatatca tcccctaaaa cacttgtaaa atatttcata
    91381 gcattataag gtcttcccgt aactaaggct accttgatac ccttttccat gacttctttt
    91441 agtgctttaa tattttcttc tgatacttca aatcctttac ccatcaaagt accatccata
    91501 tcagtacaaa ttaatttata tcgcatttgt atcacatcct agtaagattt ttctaatatt
    91561 tcaacaaggt cttctttctt tccaaaaggt aaaaatccta aaactggaca gcttgttatt
    91621 tgttctaatt gttcctttgt tacattaaac tcagacattt ttgtcttaag tcccactctc
    91681 tttaaaaaac tttctatttc atttcctaaa gttttagcta cttcatcatc ttccactttt
    91741 tctaattctt ggtttagcat tctcgctact ttggcaaatt tctctatatt atccttatag
    91801 aacttttctg caaattttgg gaacactata gccaaagcct caccatgagg aatatgtgta
    91861 actcctccta ttatttcact tagtggatgt ggtgctgctg ctccagcatt tgccagtgaa
    91921 cttcctccta atgtatctgc tactgctaac tttgttctgt attctatatt atttttatct
    91981 tccattactt taggtagata gttaatgact aattccatag atttttcaga cattatctct
    92041 gtaaaatcat tagcatttgg atttatataa ctttcaaatg catgagtaaa agcatcaaat
    92101 gctgttgatg cagtaattct ctctggcaga gttaacataa gctctgggtc aactatacat
    92161 tcttttgaga aacaattttg atgaaatatt gtatttttct cgcttcctct cgatattact
    92221 gctgcttgtg taacttggct tcctgttcca gaagtagttg atacagctat taatggtaat
    92281 tctttttcac ttaccttatc gtatatttta aatggatttg tatatgtact aaacatataa
    92341 tcccaatcta tcttttctaa accaaaagtc aatgctaata cttttgcagt atctatactt
    92401 gaacctcctc caacagctaa aacaacatct acagattctt ttttagctaa ttcaaaccct
    92461 tcatttatta attctacagt tgggtttggc tctactctat caaagtgtac aacttctata
    92521 cctttttcta ttaaattcaa tgtaactctt ttatataact tgtctaatgg ctctacattt
    92581 ggagtagtaa ctaacaaaca tttctttcca tattttccta ttattctagg taattcactt
    92641 aaagttcctt gtccaaaatt tattcttgat ggttgataaa agttaatcat atttttcctc
    92701 ccttaaatta ttgccttcat attcaaatta tacatatcat aggattttta aggcaatacc
    92761 ttcactgtta actcttattt actaaagctt atggcaatta ttagacaatc aatgttttat
    92821 tattaccata tcattatgta aattttatta agtacccatg ttataatttt ataatcaatc
    92881 ttattgtata attgacttaa taataaaaat agagtatata cactttttta tgacaaatag
    92941 cttaaaggag aattaaatta tgaaatattt gatagacagt gctaatcttg atgaaattca
    93001 aaagtgttta aagtatggat ttaagggaat aacagctaat ccatctatgt atcttaaaga
    93061 gaaagtaaac ttccatgaat ttattgagac atgtgctaat ttaaatccag aaatattaac
    93121 tgctgaagtc attggaaata atttatacga attaattaat tcatgtgata agatattaaa
    93181 tataaataaa aacactataa taaaaataaa tttctctgaa gttggcttag aacttataaa
    93241 catattaaat agtaaaggtg taaaaactgc atgtaccttg attttcaatg taaatcaagc
    93301 atcattagct ataaatgcag gtgctgatta cctattccct tttataggta gaaatgatga
    93361 aaatgggaat gatggtataa aaaaccttac agaaatatgt aaccttatat caataaatgg
    93421 atataatact aaagttgttg cagcttctat taaaaatgta ttccacttaa ctcaagcatc
    93481 tctttgtgga tgtgattatg cagctgtaac atatgattta tttaaaaaag cttcttttaa
    93541 ccagcttaca atagatggtg ccaatacttt tgaaagagat tggtccaagg ttaataaata
    93601 gtaactaaga tttaggaggg tttgcattga acaaaagatt attagatatt gctgaattat
    93661 tactcaacag ctcagactat attactgtag atactattgc cgaagaatta aaagttagta
    93721 ataaaactat tcgtaatgac cttgttattt tagatgaatg gcttttagag tttaatttat
    93781 ccctagataa aaaaactggt tcaggggtta ttattctagg taatgaagat ataaaactta
    93841 aagttattag agatatcaat gataaatcaa attgtatata tgcatactct cctgaagata
    93901 gaaaaaggta tattctaagt aaattattta ttaaaaattc taagtttagg attcgtgata
    93961 tttgcaatga actacatgtt agtagagcta ctgtgcataa agacttggta gttattcaaa
    94021 attttttgca aaactttaaa gtgactctag ttagaaaaac caataatgga gtatatttag
    94081 agggaaaaga gaaagatatt cgaaaagcaa tttttgaact tgctacggtt aataaaagtt
    94141 atactgaact taaagaaata ttattctcga aatctaatga atgcaaagat accccttcaa
    94201 caaaaatatt taaggagcta tttaactatg attttgagaa attatctcaa atcactctac
    94261 acaccttaca agtagaaaaa agtaacctta gtgatgagta ttatataaac ttcttaatac
    94321 atatagctat atgtattaaa agaatttcaa ttaaaagata tattaactta tctgaaggtt
    94381 tttttagaga attattagaa catgaatact ttgaaaaatc aaaaatttta tgtgctaacc
    94441 taagtgaagc ttttgacgta gaatttattg atgaagaggt ctgttatatc cttcttcata
    94501 tagaaggatt acttaaatca ataaagaaaa ctactactct tgaacctctt aaaaatgaag
    94561 aaattacaga gtataatcta tctgaagcaa tagctgttca ttggggaagt atactaaatt
    94621 taaacttaaa ggatgattta atattaataa agtctcttgc taatcacctt aaatcagttc
    94681 tacacagaat aaactatggg tttactatta caaatcccat attaaatgat ataaagagaa
    94741 catttcctta tacttataag gctgctaaag agtctaatac tgttatcaaa cagttgatga
    94801 attatgaagt caatgatgac gaaataggat atcttgcttt atatttaata tcagcaatag
    94861 atagaagcaa atctcccctt aatactattt taatatgtca ctgtagtgat ggtgtatcta
    94921 atttattagt ccaaaagtta agttttgaat ttaatcagat taatatagtt aaatctatac
    94981 ctctatcttc tatttcattt acgaactttg atgatgtgga cttaatacta accactgctc
    95041 ctgtagactt tgaacataat gctgaactga taaatataaa tgctctttta agtaagaatg
    95101 atatttctag acttagtaca attataaaaa aactatattc tgaaaaaaat aaaatattat
    95161 cttataaata aacaaaaata ggcttgtctc aacatagaga taaacctatt tttcattgtc
    95221 taaatgataa aaatatattt gatttcatag aaaaagtgcc tcatgaacta aaaaattcat
    95281 tttgagacac ctccattttt tatatttaag ctttttattt aagcttttat attttttaaa
    95341 cttttatatt taaagtaaat tttattattt ttattgagca caagcattat ttatattatt
    95401 aatttcttca gtattcttac caaactttgt agttacaaat cctattgttt ttattatgag
    95461 taataaagat atcaatgaat atatagatat cataaaattc ttacttatta ttccagacgc
    95521 tactattata aatccatcta gcataaataa tataactggc aacttcagaa acttaattac
    95581 cttattaata agcattgcaa ctaaatcagt tccaccagta ctacagcccc ttattattgc
    95641 tatccctata gcagttccta ccaataaccc acctatcact cctgctacta atagattgtc
    95701 agttatgtga gtttgtggta ttacttttaa gaataatggg cccataagag ttatatataa
    95761 tgtttttatt ccaaaacctt tccctaaaaa taataatccc attactaaaa gtggcataga
    95821 tattcctaat gatatattct caacaggcat tgataagaat gtgctaagta cgactgataa
    95881 tcctgttatc cctcctggag ctaatgtatg ttctgcaaag aaaaaattaa ctgctaatgc
    95941 cattaaaaat gctgatattg ttatcagtaa ataatctttt atcatttctt ttttcattta
    96001 ataacctcct atgattatat tatttcagta taaaaaatca attaaattag tctagcttcc
    96061 tgtagttttt cataaaatta atgcttcctt aaaacattaa gaaagcatct cttttatcat
    96121 agtttattat cttattctaa accaaacttt gtagctgctt tatctatagc ttttctacaa
    96181 ttcttaacac ctgctgttat accatcttta tccttgaata ttgctgaaga taatattaca
    96241 acgtctggat tacattctat taatggctcc atattgtctg ctcttagtcc accatctatt
    96301 gctaattcac acttaggatt cttttcgtct atcatttttc tagctctttt tactaaatca
    96361 acagcactct ttctccatcc ccagttatct tttccatcag tttcatcaac accatgaacg
    96421 actatttgca atctatctat atcatatata gcttcatcaa caaaacataa tggtgtgtaa
    96481 catccaattg ttaatcctac tttcatacca aattctctac agtaatttat tatgtatgca
    96541 agaggagcac ctaaaaaatg ttctgctggt attatcaaca agttacatcc tgctgctgct
    96601 attttttcta taaataatct atcacaatct cttgtgtata tatggcattc tattggttta
    96661 tctgtcactg gtcttattgc ttctattatt tgatgaccac ccataagttg catatttttt
    96721 aagtcatgca tatctgctgc atctgaatgc acgtagtcta cacctgcatc cattgcttct
    96781 ttaactacgg ctgatatatg accgtaattt acatgtgcta atcctgctgc tatttttatg
    96841 tgtttcatat ttgtatacct ccatatttta ctttaattag tattaaatat tagtttttga
    96901 tattttttta atatttttta atccagtatt acttttattt agcattactt ttattgctgt
    96961 atatatttct tttatgaact tattctgctt ttgttaactg tgaacttatt ttgctttgta
    97021 aattaatatt acactgatat attttttttc acaacacttt gactactcct taaaagtacc
    97081 tttatattgt ggtaaattat agacattaat tgtatataaa aagttagttt tttaccacat
    97141 tcttatggca tttattgtct atactaactc aattgatata gctagttcat ttaatatata
    97201 atcagactat aaatataaat ttactcgata aaaagtacca ttcataacaa tattaatgaa
    97261 agggagatgt aaaatgagaa actgtattat tgcccaatct ggaggcccta cagctgttat
    97321 caatgcttct gcagttggta tttatgaaaa aaatttagaa actaaatact ttgataaagt
    97381 atattttggt atcaatggga ttgaaggtat attaaacaaa aatataatag attcagactc
    97441 cttaaacaaa gataatgtat taaatttaaa gcaaacacct tcgtctggtc ttggttcttg
    97501 tagatacaaa ctggctgatt ataaaataaa ttcttatgat tatgatagag ttataaatat
    97561 actagatgaa tatgaaatag atacattatt ttatataggc ggaaatgatt ctatggacac
    97621 agtgatgaaa ttttctcaat actgcaaaaa cactacttgt aaaataaaat ttataggtat
    97681 tcctaaaaca atagataatg atttattagg aactgacaac tgtcctggat ttggttctgc
    97741 tgcaaagctt atttctacac taataatgga aacatactta gatttttcta tatacaaaaa
    97801 taatggtata tttatagtag aaactatggg tagagatact ggatggttag cagcttcttc
    97861 ttcactagct agacttaatg atactccact tgttgattta atataccttc cagaaattga
    97921 tttctatgaa gataagttta tagaagatgt tagaaaaata tttaaagaaa aaaataaggc
    97981 ttatatagtt gcgtcagaag gtataaggga taaatacggc aactttatat gcgaacaaaa
    98041 aacttctgct catgataaat ttggtcattc ccaattaggt ggagtaagca actatctaaa
    98101 gaatcttata gtatcatcat caattacaac aagagtaaaa accttagaac ttggtgtaat
    98161 acaaagatgt gctatgcatt tagcttcaga tactgattta aaacaagcag ctgaagttgg
    98221 tgcatatggg atagaactat ctaaaaaagg atatacagga gttatggcta tcattaatag
    98281 aacatgcaat aatccttata agtatgaagt tagtcatact gatatttcta aaatagctaa
    98341 caagacaaaa tattttccta aagagtggat aaatgaagaa tgtaattata taactgatga
    98401 agccctaaat tatctatatc cacttattca aggtaaacca gatatcaaat ataaaaatgg
    98461 actaccttat ttttcaatta tttactagga aattattata atttgatata cactcaattc
    98521 tatcgctctt aaatacctaa gtggctgtta aataaaatta taaattgtta tatgacagtc
    98581 acttaatcgt ttaattattt aactgtttag ttttttaatt ttttaatctt ttttaatact
    98641 aatacgattt gttgtaataa tatctcacac ccattttcat tttggataga ttataattag
    98701 ttagacaata aatattttgt catgatatta ttatatatag tgatacaaat agaaatactt
    98761 ttatcatggc tagaaaaaca aagattacac aaaggattta aaaatcaaac aacttcaatt
    98821 aaaataaatg gttaaaataa cttctaaatc aactactata aacaataaaa gaacataaag
    98881 tagttaagtc tacaattata aaattagtaa gactataata acttaaataa aattaaagtt
    98941 aacaaagact attaaagtta gcaaatattc ctctacctaa ataattgctt tttataaaga
    99001 gttatttatt ttaattgaat ttaattgaaa tacgatttta actagaacaa tagattaatg
    99061 taatatttaa tataaaataa ttataataat tgaaaaggaa gtaatctatg atgaaaatag
    99121 cagtcataac aaccgaattt ttaaaagagt ttgtagataa ttctataaaa aagttaaata
    99181 ttaatgcaga aattgaaata tatatctata gagatttttc tcatgttgga gatttatatt
    99241 tagaaataga agataggttt gatggatttg cagttagtgg ccccatcccc aaaaaagcta
    99301 ttacaaaaaa ggctggaact attaaaaaac ctctagttga ttttggtact gacttacaaa
    99361 gttactatga tatgtttcta aagcttatct ttaaatataa tacattagat ttttctagag
    99421 cgtactttga cttaacagac tgggcagata atccaaaaga tatatcatat tatttatcaa
    99481 atggcacatt tggagactta atggatagta ttgatgaaaa tgcatctaaa atgagtttat
    99541 ctgacatagc aaaacttgaa aaaaagattg caaaaaaaca tattaatcta tggaatgaag
    99601 ggaaaatcga tttttctact actcgtttta gtagtattgt tcctatgtta caaaatgcag
    99661 gagtaaactt tcatttcata taccctgata tagatttatt aaaaaatact tttaataact
    99721 taataaaaga tattcattta catagaatga agggaaatca accaagtgta atatatataa
    99781 cagttaaaga tacaaattat gatgactcta ctctagacca agtttataaa atattaaata
    99841 gtattaaaaa agataaatta accgatttta taattgaaaa aaatagtaat tcttttaaaa
    99901 ttttcactaa atgtgaaacg attaaatcat taactaaaaa ttttactgca tgttatataa
    99961 aagaatctat tgaaaatagt acaaatatta aagtatgtgt tggatatgga attggtaatg
   100021 atataaagca agctatgtct agtgccataa gtgctaataa ggaatctaaa ataaatcatt
   100081 taaattacag tttcttagtc aacgaaaatt atgagacaat aggaccttta ctgtgtgata
   100141 agttacttac tgtttcaaat aaagtaactc cacatataaa tacaattgcc aaaagttcta
   100201 aattgtctac tcttactatt caaaagatta tatctgttac tgaaattcta caaagagatg
   100261 aagttactcc taaggaatta tcttcatgtt taaatgtaac agttagaact gctaatagat
   100321 ttctaagtag tctcttaaag tctggaaacg ctactatatt atatgaaaaa caaaactcaa
   100381 caaaaggtag acctgaaaga gtatacaaat tatttatatc agaaaataaa tattaaaatc
   100441 caaaatgcat aaaaatattt tatcatctaa tattaagtaa aattatatat gactttctaa
   100501 aaggtatatc tttgcatctt tttaagatat accttttata atatttaata atattttatg
   100561 ttattatcta ctaaaattat tttctaacca ttttactgca caatgagcaa ataaagctga
   100621 accataaact aatccctctt cattaaaaat tgctttagga ttatgcatac caaaattata
   100681 tccctgacta atacttccca ttccaatcca taaaaatact cctggaaccc ttagtaaaat
   100741 ctctgaaaaa tcttctgaac ccattgcaga tggaaagtct attacatttt catttcctat
   100801 aacttcttta acataagata caatctcatc tcctacatcc aaatcattta taactgcagg
   100861 agtccccatt ttaaattcca ctttagcatt tcctccaaat gatttagcta ttcctgtaga
   100921 tatttcaata attctatttt ttaatttttc tctaacagat tggtcaaatg ttcttaaagt
   100981 acctgacata gatgctttat ttggtatagc atttggtacg cttcctgcat taaacatacc
   101041 aatagttaaa actacaggct ctttctgagg tttttctctt gaaagtatag tgtttaatgc
   101101 tatttgtata tgtgacatta tgtttattgg gtccactcca aattcagggc ttgctccatg
   101161 agttgctttt ccttctactg ttatttcaaa tatatctgca gatgccatag ctggaccacg
   101221 tgaataagct acttgacctg tgttaagaaa tttacccacc atactgtgaa atgccatagc
   101281 tgcatcgacc tgaggatttt ctaatatacc atcatcaatc attgattttg cacctctggt
   101341 agtctcttca tctggttcaa atacaaactt tactctacct ttaagtaagt gcttattatc
   101401 cataagtatt ttagctgctc ctaagagcat tgctgtgtga ttatcgtgtc cacaactatg
   101461 agatgcatct ttattcttac ttttaaaagg taaatccgtc tcctccataa taggaagtgc
   101521 atccatatct gcccttaata ataaggtctt tccaccattt ttactgtcta aaacagctac
   101581 tattccatta ttagacgtca atttcggaga atatcccatt ttttctaaag tactggtaac
   101641 aaaggttact gttttcggta gattgcaacc aatttcggga ttttcatgta aatatcttct
   101701 ccatctaata atttcccctt ctattgactg cgcttcttta aaaaaatttt tcatattcct
   101761 tcctcctaat cagatagtca gcaaaatctc actttctttt agtaatgaaa tgatgctgat
   101821 ataaaaatta taattttata tattaaattt catgtctttt taaggagttg gaatatcatc
   101881 tggaatagga catttatatg ttttaccatt catagattta tcaaattctt cttttgcctt
   101941 tttagctatc tctggattat ttaatatttt agctccaaac atagccataa tctttgatgc
   102001 atatatcata cctttttctc ctatagaact tcctgcacaa gatgtaaact gccagctatg
   102061 acctggtgct cctagattcg tacaccctgt aaaaaagtat gctgtcggaa ctatatgcat
   102121 tacatctcca atatcagtag agccataact attaaagttt gtaacatttc ctccaccata
   102181 atatagatga gttccttctg gcaaattata tttacttatc atagccttat attgttgtgg
   102241 gctttgtcta tctaattcag ctgcaaaatc caattcctct cgagtccaag gctcttgttt
   102301 aatctcattc atacattctg atacaagatt tgctaaaaca tgattgttta aagtattata
   102361 acaccctcct aaaaactcta cttcaacttc agtttcagtc atcattgcag ctccttttgc
   102421 tacctttaca agtctttcat atgtactttc tacagcttct ctacttaaag ctcttgtata
   102481 ataccatact gatgctttat caggaactat gttgggtgct actcctccat ctgtaattgt
   102541 ataatgaatc cttacatcag aagtaacatg ttctctcaaa taattagctc ccacattagt
   102601 aagttccaca gcatctagtg cacttcttcc attttgaggg tctgagcctg catgtgcagt
   102661 ctttccctta aagtgaaact ttacagagtt aacagctgtt gaagtaccaa ttgtagcttc
   102721 actaatttta tttggatgaa aatttatagc taagtctaac ccttcaaacg ctccacctct
   102781 agccataaat cctttacctg ttaattgttc ttctcctgga catgcataaa atactatagt
   102841 cccacttaag ttattttcta tcatctctct tttaagccct actactgccc ctacatgtgc
   102901 tgtacataat aaattatgcc cacatccatg accatatgca cccaattcaa atgcttcttg
   102961 ttttgttgaa actttttgat ttaaaccagg taatgcatca aattctccca taaaacctat
   103021 aactggttta cctgaaccaa aactagctct aatagccgtg gctaaacctc ctacacctac
   103081 ttccacatca aatccttcac ttcttagaaa gtttgctgta ttttcacatg ctttaaattc
   103141 tttaaatgct ttttctggat tttcccatat tttcttactt aaatcatcaa gtttgaatct
   103201 ttttttatct atctcattta tagatatact tcctatcatt ttctattcct cctataaatc
   103261 tatttactat caaccaaata taattggacc tattatacta gcaaatgcca ctgatgcaat
   103321 ggttacagta acaaatcctc ctataatcat ctttggtaat aaataatctg ttgccctttg
   103381 tttttcttct tcagttcctt ccatagcatc aataccttca ttggaaatta tctgtgttgc
   103441 aggataagct agcatacaag ttacaccaat tgcagctgac attcttggag aatatcccaa
   103501 tagttttcct acaattgcag taaatagtat tataaataca gagcctacaa caagtattcc
   103561 tatagttgga ataatcatcc caaacaatgc tgttggagtt accttagcaa gtcctccagg
   103621 taacatcaac atacaaccaa acattataat tccattagat tgagatttat ctaaaattcc
   103681 tttttctaaa aaacctattc gtgtaaaaat caaccctact aacaaacatg ctatgttggg
   103741 atttaaataa tagtttgcag gggtaaatcc tggtattaaa gtagccaatc ctacaaaatt
   103801 accaatcata gcaacaaatg aaagctttgc aagatatact aaagtagatg attttttacc
   103861 taaatcttct ttaaaaattc tcatacttgg aagtttaaaa ttactttttg actcatcttt
   103921 caaaaaatcc ccgttatctc ttttaaattt taattcttta tttatacaat atgtagttat
   103981 cggaatgcca aagaactttt gaaatgataa tactagaatt acaaatgcag caagttcagg
   104041 tctatttgca gcttctgcaa cagttgttac gataatacca gcaacagtag aacccgctat
   104101 tggaggtgct gctattaaag catactctct accaaataac atactaccca ctgttaaaca
   104161 gccaacccct attcctacaa tacctactaa tgcaattaca accgttttcc attcatgaca
   104221 taagtcttca agatttataa gtgttcctaa gttagttatt aataaagcta taccaaagtt
   104281 gctcattgca gctaatatcc ctgatgctcc tgtaatgtct tttggtaaaa tatttgtcca
   104341 aaatcctagt aaaaatataa tacatacaaa taacaatgtt gaaattgcac cttttgtttt
   104401 cttagataaa aactcactaa aagcataaat cattacacat acagtaaagc aagtaagtgg
   104461 attccaaaaa ttttccattg ttgtttcctc ctaaatataa taatttttta tcaataaaac
   104521 aataattata aaatgtatat tatgcagtta ttcttaacta catatggtat agcttgatat
   104581 tttttgatga tattatatac gtcctaaatt attcctaaaa tatctaaata aatataacta
   104641 gagttaactc tctaaatatt aactatagtt atcaacttac tagatttctt tttgattttt
   104701 actttctaca taattttacg agttagaatt gtacttcaac tattctctat attagtatac
   104761 atgttggaag acttatattt atttaaatat tagatataga atatattttt ataaacgtct
   104821 taaattattc ttaaaatatc taaaacgaaa taataatata cccattaaac caatattatc
   104881 agaatatact tcactttaag tcttctttat atagaaattt tatctattag tgcatcccct
   104941 cccttgtaaa ttagactatt tctaagcgaa tttagatatc ttattcctag agactattac
   105001 taaaaacaaa aattatttat tatattaaat caatgataag ccatacttta aaattctttc
   105061 tatacaagta taatttatca tataatgaca tctatacctt tatctttata gtagtcctaa
   105121 attattctta aattgacaat aaaaataatt tcactattta taaaaatact tgtttttata
   105181 ttgtcaaact attcttaata tagattataa ttttaaatct tttctttgtc aatatattct
   105241 gacatttttc cagaaaattt ataaagttat atagtgagta aatcatacta tttttatata
   105301 atgagtaaat tatactatga atatgtctaa atatttactt aagtataaaa ataaaaaatg
   105361 tgtattctcc tttttatagt aattttaatt gccattattt ttaagaagaa tacacacttt
   105421 actttaaaga ccctatactc tattttaaat gctttactag acactaatta acattagttc
   105481 ctaacttcta tttatcttat tcctacccta ctactatatc cgtagaaaaa tctaaaactt
   105541 ctccattaga ttttattact tctttgtacc aatcaaatga ttttttctta tatctcttaa
   105601 aacttccttt gccttcatca tctaagtcaa catagataaa tccatatctc ttactcatct
   105661 gacctgtagt tgcactgact aaatcaattg gtccccacat caaatatcca aaacattcaa
   105721 cattatcttc ttcaattgca gacttcattt gagatagatg cttacttaaa tattcaattc
   105781 tataatcatc atttatagtt ccatcttctt cgattttatc atatgcccct aaaccatttt
   105841 ctgtaattaa gataggtaat tgatactttc tgtaaatata gttcaaggta aatcttaaac
   105901 ctatagggtc tattgcccac ccccacttac tttgttccaa atatggattt tgaatcccac
   105961 caaataaaga tttatcacct gataaatttt cttttggagt agatacactt gaaaaataat
   106021 aattaagtcc tataaaatct aacttacctt ctttaaatgc ttttttgtct tcatcagtca
   106081 cttcaatagt tatattattt ttttcatatt cttttaattt atattgtgga aacttcccat
   106141 tgcacattgc atcaatttga taataatcac ggtcattatc taaaaatgca tttaacacat
   106201 tactaggatt acaattgtat ggataaattg gatttagtcc aaatacacat ccaattttat
   106261 tgttgggatt gatttctcta gccaactttg caacctttac acccgccaaa gtcatattat
   106321 accctacatt tgccaatgtt tgaaccttat tttctatttc actatactta atacctgcta
   106381 tcatataagt aaaaatatcc gagtgctctg tttgagggtc aatatggttc atctcattaa
   106441 atgtaaccca gtactttacc ttatcatcaa atcttcttat tacagtctca ctgtacttta
   106501 aatacaaatc tataagtttt ctgttattcc atgaaccata tttatgtact aaattcatag
   106561 gtaattcaaa atgatatagt gttacaatag gttctatatt attttctatt aatgtatcta
   106621 tcagaccttc atagtattta atccctaatt cattaggatt ttcatcatct ccatttggaa
   106681 aaattcttga ccaatctata gatattctta atgcactaaa tcccatttct ttaaataaag
   106741 ctatatcttc tttatatcta ttataaaaat ctattccatt atgagatgga taatctaatt
   106801 tttcttctat tttatcagta attactcttg gcgtttcata agagccctta gttacaaagt
   106861 ccataattgc aggtcctttg ttatcactat cccatgaacc ttcacattga tgggctgcaa
   106921 tacttcctcc ccagaaaaat gtatctttaa tattcatgaa ttttccctcc taaaatttat
   106981 actattacag ttaataattc ttctgattca tcatttgatg agattacatc taaataatcg
   107041 ctagtatttg taactacagt tattatagta gaatcaaagc cttcctctat aattttatca
   107101 gattcaaata ctgctaaagc atctcctttt ttaacccttt gattttgtgt tacaagactt
   107161 tcaaagaatt ttccatctaa gtttacagta tctatcccaa tatgaattaa tatttctaat
   107221 ccttcatcag tcactatacc atatgcatgt ttagttggaa atactatagt tatagttcca
   107281 tctacaggag atataacagt tgattttgat tcactaggta taactccaac ccctttacct
   107341 aatgctccag aggaaaatgc tttgtcatta acttccccaa gtgcaattac ctgacctttt
   107401 gcaacatttc caatactaat agttcttgaa ttgttctcgt tgattattag ttctaattct
   107461 ttttcattat cacccttaac ttcttctttt tcatctgaag gtattcctag taaataggaa
   107521 gctgctgttg ctgctacaaa tgatactact acacttatta tcataaatgt aaagttagat
   107581 acctctcctc caacaagata cgttggtaat gcagctaatc cccaaaccat tccatatgtt
   107641 ttaacttgag ctaaacctgc tattaaacca cctatacctc cacctatcat tactgctaca
   107701 aatggtcttc tatatttcat aaacacacca aacactgaag gttctgtaac tcccataagt
   107761 gcactaaaac ttactgtacc aaatagttgt ttttgttctt tattcctagt ttttaagaaa
   107821 tatccaaaca ttgcaccaca aactgcaata tcagatattg ttgcagcgcc cataaaaatt
   107881 gggtcatacc ccaatgttgt cacagaattt aaagatatag gcatagtaaa gtttgctgca
   107941 ccaaaaacta ttaagagtgg ttgtaaagct gcatacagtg caacaacact ccaattaccc
   108001 aatgtatcaa ttaaaaacat acatgcatag tttaatccat caccaatcca cataccaata
   108061 ggtccaaata cagttaatgt aactgataga gttattatta aagataacac tggaactaaa
   108121 aaatagtgta atgctttagg taatattttt ttcaaacctt caattataat tcccattgcc
   108181 catactccta aaagtattgg aataaaactg tttgcataag ttgtagcctg taaatttata
   108241 ccaaataaac ttaatccttc tacaccatct attgatgaag ataataacgt aactgctaac
   108301 actactgcta tatagggatt tacattaagt ctttttgctg atgctattgc aattaatact
   108361 ggtaagaagt gaaatgtagc acttcttaat gtatctaata tttgatatgt aggactgtca
   108421 ctctgaagta tgccagacat atttaaaagt gctaatatac ttgcaagtat accagctgca
   108481 agtagtactt caattactga agtcatagtc tctgagacta ccacaaagat ggaattaaat
   108541 atacctttga tacctctaat tccctttttt ctttcacttt ttatacttga ttcacttgaa
   108601 cttaaaccta tcatagacat aaactcgtta tatacatcta caacatgagt acctattata
   108661 atttgataag caacatcatt agaaactaca tcaattactc cttttaattt tttaatttct
   108721 tctgtttgag cgatactcct atcatttaaa gtaaatctta aacgagtaac acaatgcgct
   108781 accgacttta tattttcttt tccccctata agttttatta tattttcatt taaatcttta
   108841 tatttcatct gattttgcct ccagtctttg agtcacccta tttatatgca acattaaata
   108901 agtttcttca cttatagata tatcgacatt aaattgtgat tttatatatt ttcttatctt
   108961 ttgaacactt ccaaatgact ttggataaag ttgacttact tgtttatata aatctataga
   109021 attatcttca tctattgaag cttcatccga cataattctt tggataaagt actgtagatg
   109081 agtagtaaat ctcatataat ttgttgaagt ttcatctagc tctacattaa aatgatattt
   109141 tattatagaa actatatctg ctaaagttct caactctaca attgtactat catgagactc
   109201 tttatttacc tccatattta caaaatgaag tgctattgat actgcctcat catcaggaag
   109261 attaattccc ttactatcac caattaattt tagtgcatgc attccaattt caaaatgctt
   109321 tggataaaat cttttaacat tccataccaa aggacttttt ataaattgat tcttttcaca
   109381 tcttttaagt aaaaactcta aatggtctag taaggttaag cttagataat cacttgcctt
   109441 tatatttaaa gctttctcac catattcaat tatttcatta ataagaacta tattattgga
   109501 gtctgagttt tgtagtagat aactaaagtg ttctagcata tcgtatgaat ctagtatata
   109561 tgttctctct atttcatttt catttattac ttgtcccact ctttttttaa agccaattcc
   109621 tttaacaaat acaataattt catttttacc tctttttact aaggctacat tattatttaa
   109681 aatctgaatt attttcatat attcctcctt tcaataaaaa gaactcaagc atatatgtat
   109741 agagtatccc tctatttttc acatatatac ttgagttctg cctgctaatc agtaacatac
   109801 tcaaaattat gactacgtcg ccataattaa aattcttttt tgtttaattt catattctat
   109861 atgttatact atccatataa atctgtcaac ggtttcctag atattttttt attctataac
   109921 tacaagctct gttatgcgat tatctgacaa ggtttatata ctaaattgat actattttac
   109981 cgtcactaat atttataata ttgtctgaac cattatctat tttactatta tgaattatca
   110041 tagtaatgct tttaaatata atgaactgta tgttaacaaa taaattctta agatatatta
   110101 acatataaag tcttaagttt agttttattt aatcactatt aagatatatt aataggtaaa
   110161 gcttcaaatt tagtttcatt taaatgctag taagatatac taatatataa atacttaaat
   110221 ttagttttat ttaaacgctc tagtgatatt tttaaataaa ttttaataaa aatcattcta
   110281 ttttgtcata aatcatttat ctggcttata tttaagatat attagtggat actttacact
   110341 ttttaattcc tcattacttc ttaaaagttt attattattt tccatatcat aaatttgtaa
   110401 cattacttta tttacatata gagcataata attatcacta taaaaatatt gatactcata
   110461 tcgagggtca tctttgtaat acactttgta tagtattcct tcgtaacttg ccttcttggc
   110521 tttttctttt gtaatacttt ttatattatc ttttgaaata tcttgtttta ccatatactt
   110581 atcaatatat gtttcagcat ctttccatgg tttaatgcag tttttatata caacaaaccc
   110641 tgttacactt ataataccta taattaatac tataaaaata actttatatt ttttcatatt
   110701 aatcctcctt catttattat ttaaaactcg atataatgca ctaaaaaaag gatgttatct
   110761 tttttattaa aatataacat ccctcatatt tagcatcaat atatatgccc caactggtag
   110821 gttaaaagac cccactgtca gtactttgat taaattacat gtatgtatat atatttttaa
   110881 caaatctatt atatgtcaac ttgtctacta ttacatataa tctgtaatat tacatctgct
   110941 gctttttttg agcctcctgc attataaaag ctttttgata gtttagttgc attttcttta
   111001 tattcattgt catttataac ttgaaatact gcttttttaa tactttctga cttatcctct
   111061 tttaacataa ttcctgctcc caaatgaaca actctcttag ctaccattct ctgctccgaa
   111121 tgttgaggaa ataataccat aggtactcca taatataaac tttcattaac actattcatc
   111181 ccagaatgag taacaaacac atcagttttt tgaagtatag caatctgttc aacactattt
   111241 ttgacctcaa aattatttgg tatatttcct aaacttttaa tatcagtact tctaccaaca
   111301 gacataatca catcaacatc agaatcttta aatgcactta tacagttttt ataaaagcta
   111361 acatttttat tattaattgt accaagcgaa atatatatta gctttctttt tctctcttta
   111421 ggttcaataa tcaactttga tactgatgga cctacaaatg aatacttact agagaaggtt
   111481 tctaccattg gttgaaattc ttttgatgta tatacaatgg tatccgtatc attatcatta
   111541 gaaactatag aaataaaatt ttttacttca tacccttttc tttgtaaaag ctttattttt
   111601 ttattaatgc gtcttacacc aaaaatcata cgtataattt ctataaagtt ttgtttcatc
   111661 aactttgctg tatgtttatt aaatgcaaaa gttgttgtag agcatacata tggaatatta
   111721 agtttttgtg caaataactt tccccaaaaa cttaatgaat ctgatacaat gcaatctgga
   111781 ttaaaatctt taagttctct acaaactttt tcatctaaag aaatagtagt atctactatc
   111841 atctcaatta atccaggaaa atccttacca atttttttct catctccagg gagtaattct
   111901 ggaaggtatt tatcacaaca aataaatttt gctccagcac cttcaatttt atctttaaat
   111961 tcattaaaag aataatacaa tacctcattt cctctatcca ctaattcacg aactacttca
   112021 atagtaggat tagtatgacc atatgcagga atgctaaaaa atactatttt actcatattt
   112081 catacctcct tttataattt ttttaaatca ttcttcttta cgtactactc ccacatgacc
   112141 tataaaattt atcaaatcac gttgatgaac aattcctaat cctctttcct catctccaag
   112201 taccaataat ttatctcctg catttatatt aaatacttct cttgcttctt ttggaatgac
   112261 aatctgacca cgttcaccaa ctacaactgc tccaaagaaa aactttcctt taggaggtac
   112321 tataatacct gttttttctt ctgaatgatt aactaagtca tctagtttga cattgtacaa
   112381 ttttgcaagt ttaatgcaac tacatatatc aggaatagat tctccacttt cccattttgc
   112441 tattgattgt ctagaaacat taagtttttc agctaattct tcttgtgtat actggttgat
   112501 ttttcttaga ctttttaaat tctcattaat catatttttc atacctccta tgtttataat
   112561 attggattta ttatttaaat tctatcaact aatcttaaca ttcatatata tatttatata
   112621 cttttattat ataaatttat tattcaggta acatatttcc ttaagttatc gtaaacaaaa
   112681 aaacaagcac aaatctacta actgttgtta aagtatttaa gttaaggtca tttacattat
   112741 caaatatttc tacaccttta aaataacctt tatatttata atctttcata agcaaattat
   112801 tatcccttct catatacaag tccagttgat gtcttgttgc taaatttaat ggtaatcaaa
   112861 ttctttacca ataagtataa aaattactaa tgtgttataa ttttcttaac tactaaattt
   112921 tacatacatt tgaatagaat atatcaataa attactataa taaataaaaa atagttaggg
   112981 agatattatt atgattttat attttagcgg aactggtaat agccgatatg tggctcgtaa
   113041 aattgcacaa gaattaaatg atgaactgat atcactaaat caacttataa aagaggaaaa
   113101 aacagatgaa ttaatatcag cagataaacc attcatattt gtatgtccta cttatgcatg
   113161 gagattgcca atagtagtta cggattttat aaaagaaaca aaatttctag gaagcaacag
   113221 agtttacttt gtaatgactt gtggtggaga tacagcaaaa tccataaact atattcaaaa
   113281 actatgtaaa tacaaggaat ggcaattaaa aggtatggca gaaattaaaa tgccagagaa
   113341 ttatatagct ttattttcta caacagacaa agaaacatca aaacaaatga ttaaagaagc
   113401 agataaacaa atatatagga ttatttctga tatacgcaat gaaaatgaat ttgaaactat
   113461 tactcctagt ggcttaggag gtacaattaa aagtggtata ataaatacag ttttttataa
   113521 gacaattatt agtgccaaag gatttcatta tactgataaa tgcattggct gtggaaaatg
   113581 tgtagagcta tgtcctttaa ataatattaa tttaaaaaac aaaaaaccag tttggaaaaa
   113641 taactgtact cattgtatgg catgtatttg tggttgcccc actgaagcta ttgagtataa
   113701 aaataaaact caaaacagag aaagatacta tttagaataa tatattctta atatttaaac
   113761 cattataaaa tgaactatac ccattgtttt atacagtttt acatatttta accgtctcct
   113821 aaaatgggta tagttcaaaa gatagtgtct caaagtgaat tttttagttc ctaaatcaat
   113881 ctttttgtat taaatcaagt ataatttaat caccttttct tatatcattt tcactaatat
   113941 gttgtattcc aacaaatata agatttatta gctctgttag tgacttccat tgtgattttt
   114001 ttgaatcaag ataataataa tttttcgttc cttctctacg caaattaaca atctctgctt
   114061 cttttaatat cttaagatga tgagatacag caggacgaga aagatgtgtt ttttttgtga
   114121 tttctcccac tcgtatacca ttaaaatcac tctctaaaag agcaattaaa atcaattgtc
   114181 tagtctcatc acccatagca gagatagctt tgcgacattc tttaaattta gacgttattt
   114241 cttgcattct ttgttgacat tctttttcca taaaatccac cctctcttat aagtatctaa
   114301 cagttgctac ttctttctgt gcagtacgtc tatatttaac atctgggtat ccaattacta
   114361 atgttgtaag aacatgatta ctacgtttta gacctaaaag cttttttaat tttggcgaat
   114421 tatttgctac atctgaaaaa tatccactaa ataaaacacc tagaccataa gactctgcca
   114481 ttaatgccat atttgatgct gcaagtgaac cactaatctt atcttttgta attatcatta
   114541 ttgcaatagg agcatgctta aagaaaaagt tatcgtcaat ctcaacttct tttgaatatt
   114601 taatagctat atttgcaata ggttttattt ttctaaaaaa tttcactgct tcgttttcat
   114661 aaattgactt tttattgtct aaaacaatat atgatacatc ttgtgaattt ttagcactag
   114721 gggtatacct acctgcctca ataatttgct ttataatttc tgaagaaact tctttatctt
   114781 taaatttacg tatacttctt ctagatttaa ttgccattag taattcatct gaatctagct
   114841 ttggcttatt tgtaagttct ataggaggtt catcaaatcc tgtcaaggta atagcttttg
   114901 tgggacatat tgctgcacaa tgtccacaca ttagacaatc ttgtttttta attactgact
   114961 ttttattttc tataattata ttgtttactg gacaatcatt tttacaaagc ccacatccaa
   115021 tgcaaagttc tttgtcaact tctattatat gttggtattt catattcatt catctacctt
   115081 tcgtttatta gtttaaacta ttataacacg tagacatttt ttatattcat tggtaaagaa
   115141 tttgattacc attaaatttt taatttctct attaaataaa tttttcatag aattttaaaa
   115201 tatcatagtt tatacataat aaaaaagaca agcttaaaac ctaagcttgc ctttttcatc
   115261 ttttattaca aagtaaattg cacttacttc ccatacttct taacaatttt attttctaaa
   115321 attttatttg tgaatcatac tattgcatca atacaatgta aaataattct atattgattt
   115381 tctatagtta aaaaagttaa aaattatact tattattaat ttttatactc ttcttattta
   115441 atacaaagtt cttatttaac atagatttct tgtctaatat agatttctta tttaacatag
   115501 atttcttgtc taatataaat cttcaccatt tgaagcaatt actttcttat accattcaaa
   115561 acttttcttt ttcattcttc ttagacttcc attaccacta ttgtctctat ctacatatat
   115621 aaatccataa cgcttttcca tttcacctgt accagcactt actaaatcaa taggtgccca
   115681 tgtagtataa cctaataaat cgaccccatc tatagaaact gcatcatgca tagcttttat
   115741 atgttctctt agataatcaa ttctgtaatc atcttctaca taaccatttt catcagctat
   115801 atctttagca cctaatccat tttctacaat aaatagtggc ttttcatatc tatcatatac
   115861 atgatttagt gtaattctca aacctaatgg gtcaattggc catccccatt gactgtatga
   115921 aagatatgga tttttagcag atgtaaatat gtttccttca gccatatcat ctgcattttc
   115981 atcggttcta acacaacggc tattgtaata tgaaaatgaa ataaaatcta ctgtatattt
   116041 attcaataat tcaatatcac caggttccat ttctggtgta ataccttttt gctccatata
   116101 ctttaacgca tagttaggat atttaccttt agattgtaca tccacaaaga agtaattttc
   116161 tctatctaac tttgtagctt cccatacatc attaggatta caactataag gatatacact
   116221 tccagctgca aacatacatc caattaagtt atttgaatca acttcatgtg ctattttagt
   116281 tgcaattgca ctagctacaa gctcatgatg ggcagcttga tattttatct tttcaacatc
   116341 ttcaccttct tcaaagcaaa taccagcacc cataaatgga gcatgtaaaa tcatatttat
   116401 ttcattgaaa gttagccagt acttcactaa tcctttatat cttctaaaga taacattgca
   116461 taatttctca tagaaaccta tcatttttcg attacgccat gcaccatact ttttaactaa
   116521 atgcattgga caatcaaagt gtgtaatagt gactaaaggc tctattttat attttttaca
   116581 ctccttaaat atattttcat aaaattgaag tcccttttca tttggtgttt cttcatcacc
   116641 ttttggaaat attcgactcc atgcaatgct cattctatat actttaaatc ccatttcagc
   116701 aaataacttt atatcttctt tataattatg atacatatca ataccagttt tagctggata
   116761 ataatgctca tcatcaaaat caaacatttt tagtttccct gtaataactg ctgttctatc
   116821 ttttcctgtt ggacatacat ctacatttgc caatcctctt tcgtcttcat tgtatccacc
   116881 ttcacattga ttggccgcag tagctcctcc ccataaaaaa tcattcttaa aactcatagt
   116941 caaagcctcc taaaattata accaaagcac tagattatgc taatacctca atctttacta
   117001 aaataagact gtaattagat tgtcttctaa ttcaatattt ttactttctg tttctactac
   117061 atctaaaaat tgtgatgaat ttgtaataac aattggagtt acagtactat accccaactc
   117121 ttttattgca taaacatcaa agtttaatat agtttgacct tttgtaattc tatcaccttg
   117181 ttttatacat gcctcaaaac ctcttccctc taattgaata gtatttaatc caatatgaat
   117241 aagcacttca acacctgtat cagaaagaat ccctatagca tgtagactag gaaataaggt
   117301 tgtaactacc ccatctactg gagcaactac ttttccatca ctaggtatta ttgccacccc
   117361 ttgacctagt acaccagatg caaatgctgc atcctctata tcacttaatt ttaatacttc
   117421 accttttata ggacttgtta ctatttctct ttctaattta gtagacttga cttcttttat
   117481 ttcttcttta cccttatttc ttactttttt agactcttct actttctcat ctttatataa
   117541 aatcatagtt aatacaaaag ctacgaccat tgatatagct ataccagaaa gagctactat
   117601 taagttaccc attcccccat ctggttcaat cattgctgga agttcaaata ttcccattcc
   117661 tccagttata aattttctaa gattaaagaa tccatagaaa gcgcctccaa taccactagc
   117721 aatacaactt attataaatg gtttctttaa aggcaataat attccataaa ttgctggctc
   117781 tgtaactcca aatataccag atataaagtt tggtattgcc atctctttta gttttttatc
   117841 tttagtcttg aaaaatattg ccaacacaac tgccgaactt gcaaatgtac aggcaaagaa
   117901 tggcatcata acattatcat atcctaaagt cataacattg tttatatata caggaataaa
   117961 tccccagtgc ataccaaaaa taacaagaat ttgccaagta aatcctacta tagcacctgc
   118021 caatagtgga ctaaaatctc ttattgaaat tacaatttgt gaaataagtg tagaaccaaa
   118081 tgttgctata gggcctataa ctataagtgc aacaggcact gttattaata atgtaagcat
   118141 tggcacaaag aaaaacttaa ctaaatttgg aacacactta ttaaataatt tttcacacct
   118201 agaagcaaaa tacactataa atataattgg tacgactgtt ccagtataat caattgatac
   118261 aattggtagt ccaaagaaat caatatatac tggtgatgca aacattgttc ctttaaataa
   118321 agtgtacatc acatctgctc ctgctgatat actgctacct tgtatagcag gataacatac
   118381 tgcagctcct agtgctaatc ccaacattgg ttttaatcca aacttcttag ctgaagtata
   118441 tcctaagaac aaaggaagga atgtaaataa tgcatctcct gctgcattta ttaccatata
   118501 accaccagat acatcactat ataatcccat tgctacaaat aatgcattaa atcctttcaa
   118561 cataccacaa gctgccatta ttcctaacac tggctgaaaa attcctgata ttatatctat
   118621 acctttatct agtatattac ctgatttttt agtttctgaa cttgtacttg aatcatctaa
   118681 accaattatt tcaactacat ctttatagac agcttcaaca tgatttccta taactacttg
   118741 atattgtcct ccacttttca ttacagtaac aataccttcc atgtttttta atacattgtc
   118801 atttgctata ctttcatctt ttaaagtaaa acgtaatctt gtaatacagt gtactaaccc
   118861 actaatattt tcttttccac caacattgtt tactatctct tgtgctaatt gtttgtattt
   118921 tcccattttt ctcctccata tttcgtttaa attaattttt tgaaatttga aggtttggcc
   118981 aactcaatgt taccatccaa ccataagtat aattttgtta gtatcactcc tttcaatcat
   119041 tcttaatata ctactgaaaa attatttcac ttacatattt gagtctttaa ctactttagc
   119101 taaatgtatt gttaaatata taagctcatc atctgttaat atgtagttat attgtttttt
   119161 aatgaaattt ttaattttaa ctacacattc aaactcttta ttatatttag atttaataat
   119221 gcttagtaat tctttgtctg tctcaccttc atgtgcacta tctaaaagca atctttgcgc
   119281 aaaaaacttt aaatgcatta taaatctata ataaaacact gattcttcat gaaattctat
   119341 cctaaaatga tacctaacta tgctaagtac ttcttgtatt aacttcgtaa tatcagatgc
   119401 caaagtatga ccttcactta actgagcatt cactatatga aaggctataa atccagcctc
   119461 atcttctggt aattttatac ctgttttgtt ttcaataata tctagtgctt tcattccaat
   119521 ttcaaactct tctttataaa atcttttaat ttcccaaagg attgcatttt ttacatttat
   119581 tccttctttc atcctttgaa ttgcagaata tgtatggtca cttaaggata tgtaaatact
   119641 ttcatttagc ttcttgttta actttatttg tgcgtattct ataatttcac ttgataattt
   119701 catgtgttct ataggaatat tattgagtaa ttcttgtagt ttgtttgata tttctttatt
   119761 tgatattcta aatactttat ttactttagt tttatctatt agattgcctt ttgatttttg
   119821 ataaccaatt cctttaccca taacgataac ttcttcatca ttatcatcta atgtgattac
   119881 aacattattg tttaatatct tattaattat catgattatc ctccttttaa gcataaaaaa
   119941 agcttatcca taataatggg catactcctt cctaggatac tgctattatt aatgaataag
   120001 cttagcttgt acttaaacaa ttactaccta attccaatta atatgataaa acatcagaca
   120061 tattttgtca actttttatt tccatatact tcatcaatct tttatgttgc tttttgtcag
   120121 ttctaataat tattcttatt aatattaact tatttctttg catcaatata aatacaaaac
   120181 aagttatagt caataataat aaaaattcta ttaatgtaaa tagttaatat tatacttcct
   120241 ctactacatt atctgtactt tatttaacat ttttttcaac tccaaaaaca tatgtcataa
   120301 taaatggagc aaccaatgct ataaatataa ctataagtcc atttactata tttgaaatcc
   120361 ccttttcccc tgataatcca agtactgcca ttatactatt ttgtggaaca tataaagtca
   120421 catgagtaat tcctgcaaat aaccctgcga ttcctgctcc tatagatgct aacatagcag
   120481 gttttttaag tttcaatgta actccataaa gagctggttc agttataccc atgatagctg
   120541 atatccatgc agctgatgct aactgtttca tcttactatc tttgcttctt aatgctacag
   120601 ctaatgttgc gccaccttgc gctaaattag cacaaacttg agatattaat attagcgatt
   120661 cttgtcctgt agttgcaaat gctgatatga atataggagt caatgcatga tgcatccctg
   120721 tcataacgat aaatggcatt gcagctgcta ataaacaaac cattataaat cctaaccttc
   120781 cttgtagtaa atttattata ctagctaatc cctctcctaa gaaatttcct attggtccaa
   120841 ttactattaa tgctattggc gcacttatta ataatactaa agttggattt aaaattgttt
   120901 ttaacatgct aggtgttaat ttatcaatga atttttctat atatgacatc atccatactg
   120961 ttaaaagtgc agggataaca gatgctgcat atataacatc ttgaattggt actcctataa
   121021 atgatatagg gtccccactt gatacccatg cagagaaatt tggatgtaaa aacacaccta
   121081 ctactataac tgctattgat gtattaacat taaatttttt agctgcattt attgcaagta
   121141 ttataggcat aaagtaaaat gctacatctc ctattatatc taatactcta tatgtacttg
   121201 aatttgatga tagccaatta aaagtggtgc aaagagataa tataactttt atcatcccag
   121261 atgctgtaag ggctggtatc ataggtgtca tacaaccagt tattgtatct attatattat
   121321 ttaaaatact atttttttta tttttatttt ttatatcgct tttaatatct cctgtggtat
   121381 ttatcccctt atttattatt gcattaaata caacacctac ctcattacct attatgacct
   121441 gatattgagt tgaagttgag tttactccaa ctaccttatc tatagatttt aatttatctg
   121501 cattgacttt cttttcatct tttaagatga accttaatcg tgtcatacaa tgagttaagt
   121561 caattatatt atcctttcct ccaagtccat caattatcaa ttgagctact tcttcatatt
   121621 tattcttcat accttatcct ctcttttaaa ataattttta atataatttt aatccaaatt
   121681 aatcttttta ctccaagctt gtaatagtgt attgtaattt aataagctag tatcttctac
   121741 aatatggtca cattttccta gtacttcttt tttccccaca ccaattgatg tcatattagc
   121801 agcatttata gctttaatac ctgaataaga atcttctatt cctacacaat catattgttt
   121861 taaatttaga atcttgctcc cttcaataaa aatatcagga tatggttttc ccctttttaa
   121921 taaagatgga tttactatac aatcaaattc atcttttatt cccaaagatt ctaatatcct
   121981 aggtgcattc ttactagcag atgctattcc caatttcaca ttattttttt taagttcttt
   122041 tataagctca tttatccctg gtaatatatc tttatatgtt aatgagttta ttaactttat
   122101 ataaatgtta tttttttctt cacacacctt taacttttcc tctttagtat aactatctac
   122161 tttattagca gataacaata ttttatctaa tgattcttcc ctgcttatgc cttttaattt
   122221 ttcattaaaa gtttcatcta tttctatatc tagcgatttt gctatctcat gccaagcttc
   122281 aaaatgatac ttagcagtat ctgttataac tccatcaaga tcaaataaga ctgctttcat
   122341 attaattact ccctttaaaa caattattaa cttctattat gttctttgat aattttattt
   122401 ctttattatc atgtaatatg gttatatttc tacctttgat taacttataa taagatttat
   122461 attcttctat atttacagaa actaaattat ctctaaataa tatattaaat ttaatatttt
   122521 tccagtgttt aggtatcctt ggttcaaaac ttaatttatc attttttatt ttcattcctg
   122581 caaatccata tactaaactc atccatgttc cacccatatt agcagcatgt attccatcac
   122641 ttgtattttt ttgtaggtta ttaatatcca ttaatgctgt gtccataaaa tagttataag
   122701 ctttttcatg atttccaatt tcacttgcca tcattccaaa tattgacctt gacaaagatg
   122761 aatcatgagt agttattttt tcatagtatt caaaatctct cttcttttgt tctaagctaa
   122821 actcatcagg gaaaagcaac gctgaaagta cagtatctgc ttgtttattt acttgatatc
   122881 tatatattgt taatggatga taatgaagaa gtaatggata tttttctttt ggtgtatttt
   122941 taaaatccca tactgatttt tctaaaaatg aatcgtcttg tttgcttatt ttcttctctt
   123001 catcatatgg taaatacata ttttgagcgg catttatcca gtttttcact tcatattctt
   123061 gtaatttaac ttttctaaat acttcatttg aaaataaatt atgcttaaat ttatctacca
   123121 tctgtactgc atatattaaa ttatacttag ccattaaatt agtgtagtaa ttattgttta
   123181 ctattgctgt atattcatct ggtcctgtta ctccatttat acagaattta ttattttttg
   123241 attctatata atctccaaat tcaacccaaa atcttgctgt ttctataaga atttctaagc
   123301 cattttgcat cataaattct tcatcattag ttgcttcaaa atacgttcta ataccataag
   123361 ctatatctgc atttatatga aactgtgctg ttcctgctgg ataatatgca ctgcattcat
   123421 taccatttat agttctccat gaatataagc aacctttatt tattccaagt tctctagctc
   123481 tttctcttga tgcatctaag attgagtatc tataatctaa taaagctctg gcaatggatg
   123541 gttgagtata tataaaaaat ggtaatatat acatttctgt atcccagaaa taatgcccct
   123601 catagccatc acctgtaaga ccttttgctg atatattagt ctttccatct cttcctactg
   123661 attgataaat atgaaataaa ttggttttta tccccagttg aagagtttta tcgccttcaa
   123721 tctctacatc agaggttgtc caaaactcat tcattttctt tctctgaata tttttgactt
   123781 tatcaaatcc aatattacat gcttctctta aaaccaattc taatgatttt aaatgtgctt
   123841 ctgattctaa acattttaac gactccagac attctaatga ttttaaacgt tcttcattta
   123901 gatttaaatc agaatatact ctactatagc ctacaacaat ttctaaattt aacctttcat
   123961 cttttttggc atagacttct atttctcgct caatacattc atctgaaaca ttataggtct
   124021 catttgtaat atttccacaa gtaatatatg aatcaaaccc acaccataac cctaatctac
   124081 ttctttctgt aactaaattc ataaaatact tattgttata tttttttaca ttaattttaa
   124141 attgcttctt atttatagat gccactcttg ggtcctctac tttttcacaa ttaaacttct
   124201 ccatactatt ttccatttta tttttaaatt ttatttttcc attaaaattc aatggtgtta
   124261 ttgtatatga aatcatcatt aattcttcta tatcttgtga tactaatctt tctatagata
   124321 ctttaacttt tctaccacga gagttttccc atataaatga acgtttaaga atcccttcat
   124381 ttaaatctag tatcctagaa tgttcacttg taataccttt tgataaatca aagcaatctc
   124441 cttcaataga gaaatttact atatgagcat taggtaactt acagatagtc tgattttgtt
   124501 ttgcatagcc ataagcgctt tctccatatg taattggaga ttcttcataa aatccattta
   124561 catatgtacc catattatct acatactcat tattaaaatc agactcttca atattccctc
   124621 taactcctaa atgtccatta gctagtgtaa acagcgtttc attggatttt attgtatcct
   124681 tactaaaccc ttgctctata agttggtcct tagtagtaaa tattaaactc ataataacac
   124741 tcctttctta aaatgaatta tgcatgagtt tccatgtcat taaataaaat ttctccatct
   124801 gtttctatta cttttttata ccaaaaagca ctttgttttt tagttctttt aaatgagcct
   124861 cttccatagt catcagaatc aacatgaatt atgccatatc gttttgtcat ctttccttca
   124921 cttacactgg ttacatctat acatccccac ataagatatc ctataagctc tattccatct
   124981 tcatttactc caataatcat atttttaata tgttctttca tgtaatctat acgataatca
   125041 tcaattattt ttccatcttc atttacaata tcttgagtac ccagtccatt ttctactata
   125101 aataaaggta actgatacct ttcatataac tgattcatag ttattcttaa ccctacaggg
   125161 tcgttttgcc atacactatt tgattttgga agatatggat tttttatggt ttctggtccg
   125221 tttgcctttg atttttctaa accttcagct ctagctgaac tacaagcact agaataatag
   125281 ctaaaagata caaaatctac agtattatcc ttaagtgttg ataaatcttc ctcttttatt
   125341 attaatttta tttgatttga ttttaaataa taattcataa agcttggata cacaccccta
   125401 acttgaacat cagaaaaaaa caaattatgc ctttcatgct ctaaagttgc aaatacatct
   125461 tctggtttac atgtgtatgg atatgttttt ccagcagcta acatacaccc aaacttaaat
   125521 tctttattta tataccttcc tatttctata gtttttgcat tagctaataa ttgatggtgt
   125581 gctgcttgat attttttctg aagttgattt tcatcagcta taaaagttaa cccagcacct
   125641 atatatggaa tatgcattat catattcatt tcgttaaaag gaatccagta tttgacatca
   125701 tctttatatc ttttcatcaa aatttcagca tattttacat ataaattaac cactcttcta
   125761 tcagcccacc cagaatattt ttcaactaga gaataaggta tatcaaagtg gcttatcgtt
   125821 attaatggct ctatattata tttttttaat tcttttatta tattatcata aagttgtaat
   125881 cccttttcat ttggttcact ttcttctcct gttgggaata ttcttgacca agatatagaa
   125941 aatctaaaac atttaaaacc tatttctgct aacattgcta tatcttcttt gtaattttca
   126001 caaaatttaa tccctatatg acttggatag tattgattat tttcatttaa aatattatcc
   126061 tcatctaaac atacatcttt taatctctta tcatttaatg ggagtttatc aaactgagat
   126121 aaaccttttc ctccatctaa ataaaatcct tcactttgat tggctgaaat tgcccctccc
   126181 cataaaaaat ctttccctaa tttcatgcat ctacctcttt cacaatataa agttttataa
   126241 tttctatctc atatttagtt ataagatttt tttcatacta taccttttaa ataattcaat
   126301 ttaaaaatcc aattatattt tttactcact ataattaata ttgtctattt tcaatacttt
   126361 catattaaat atcaatatta gatatctatg tatataatta tatatatagc aaatacattt
   126421 ttatatcctc attattgtta tcttattctc atatattgct gtatatttat atataaaagg
   126481 atttatttcg aaatagaggt tgtattgaga actaaaattt agactttata aatgaatgga
   126541 attttcattg ttgaaatact gaaaatatat ttgatttcat ataaaagaaa gtgcctcatg
   126601 aactaagttc attttgagac actccctttt ttttccaagc tattatatct ttttttaaat
   126661 tctaatggag agactccaat tttttcttta aatactctgt aaaaagtttt tgtacttcca
   126721 aaaccaactt cttcaaccaa atctacaatg gatatattgt tattaagtaa tatccacttt
   126781 gctttttcta atctatattc atttaaaaaa gttataaatg tttttcctgt attttttttg
   126841 aaaaatttag taaaataata tacactaaat cctacttcat aagacacatc ttctaatttt
   126901 ataggttgtt tataattttt ttctacatat ttgaatatat tgttcaatct ctctaatatc
   126961 tctttagagt ttatttcata ttctactgta ttttcttcaa tttctctagg aatctgtcta
   127021 tataatatag gaattaaatt atacatttta ccttttattg cataactata tccttctatt
   127081 ttgtataggt cttcattgta gatatctatc aatatatcga aaactgactt tcttattttt
   127141 gctgaccaat ctctactaca tttttttata ctactgaata aattaattaa gctttctttt
   127201 tcctcattta ataaaattaa atcattaaaa aaagatatat caaattgaaa tactaatctt
   127261 tcacttcccg gtgatggcag tatataatga atatctcctc cttttattat cactatctcg
   127321 ccttttttta attgcatagg cttgtcattt ataaatagat ttactacacc ttctgttata
   127381 agtaatattt ctatttcctt atgccagtgt ggtgttgtta atacttctcc ttcatttgat
   127441 agactacgaa aaggaaattc atgtattaat ttaggcattt ctaaatatat tgccatatat
   127501 atcctctcct ctctagtgtc taaaaattaa tttatactat ttaaaagaat acacatttta
   127561 ttttaaaaac ctcaaattta taatttatac aatacctaca cttcataaaa tatatctaat
   127621 atttcttttt ttgtatttgc atttaaaagt ctttcaccta tatttttacc acctaaaatg
   127681 taagctattt tagatattaa tatcatatct tcattgcctc cagattgtgg catagcaaac
   127741 ataattatta cctttacagg taagccatct atacttggcc aatctacacc ttttttagat
   127801 ttacctatta ctatggatgc cttctttaca tattttgttt ttccatgtgg catggccatt
   127861 tgataaccta tgctagtaga gcctattttt tctctatgtt ttaatgcctt tataaactta
   127921 ctttttaaag ttatacttcc tgtatcgtat aatttatcta ctaattcctg tattatgcct
   127981 tcttttgtag ttgatttcaa atctaaaata atgctttctt ctgttaatat ttctctaatt
   128041 tccatttgtt ttctccaata gattattctt aaataatatt ttaatatcct ctttgctctt
   128101 gcaatctatt atatagttta tatagttctt ttgcctatat aaatttgata tttccattaa
   128161 aatattcttt aaaaaacttt gattactaat ttctaaataa atatcaatcg ttctagtaac
   128221 attattgata ttcattatcc ctttatttaa tttactttgc ttatgtatat atatatttaa
   128281 atcttttcct aatgaaatag attcatattt actccctaaa ttcacaccta ttaaactttc
   128341 catctgagct acatcaaaat taaaatatat attatcttct aaatacattc ctaataagtt
   128401 tgtatctaag ttcatacttt ttttaggttt agaaagtaaa gcatttttta tattattaat
   128461 atcattttcc attaatagta ctgatacaac tatatgtaat ttatctttca aatctaagtt
   128521 tacagtagat attacaaagt ctacatcatc taaatttcgc ttactcaact gatgcatagg
   128581 aactatatca actatagtcc attcaggaaa ttctcttttt aatctggctg caaggagctg
   128641 agatgttcca tatcctgtat gacaaactac tattactctt ttactactca tatttctttc
   128701 tattgccgct tgaaaatatg tggcaagata cgaaacttca tctatactaa tattcttcag
   128761 attatcatac tctgtcataa tatttatagt catcatacat aatcccagca catctgaaaa
   128821 tcgctcttgt atctctccta acaacgggtt ttttatttgg atatcatatc ttaatctgtt
   128881 taacataggc cttacatgag atgctagact tttctgtagt aagtcatcat ttttgagatt
   128941 tatatttaaa aatcgtgaca tattctctat cattatagat gaaacttttt cactttcact
   129001 taatctatct gattcatcat tgtaactact attattttcg ctactaaatc cagatgatac
   129061 caaaaaaata tatatgtaca taatttcatc tttcgttatt tttactctgt atctattttc
   129121 tattttatct ataagtgtac tgacattttt atatactaac tcgtccaaat tatctacaga
   129181 aatttctctt tcttcctgag attctatttg attaccttct tcgattctct ttaaacatat
   129241 aagtatatgg gtaattaaat ttatatagta gggctgattt atagtatatc ctaaattgta
   129301 ttctaattct gtaattatag tttctacaaa tataatagaa tcaatatcaa ataaatttat
   129361 caatgcacta aatgtagcag aatctaatct tgttaactca gatatatcat gttgttcata
   129421 attttcatct aataaatcat ccatcatttt ggcaatcgat ttccttatat ccacttcttt
   129481 acctataatc ttagttcctt ctaaagtttt attaagtttt aaattgtatt cttttatcca
   129541 tgcctctata tatttaaaat catttactat agaagtttta cttacataat atttatctgc
   129601 taactgattt attgaagtta tattatttga atttagtaat aaatacttta aaatctccat
   129661 tcttctctgc tctactgata aagatttatt ttccttcgat tgtatattta aactattaat
   129721 taagtctata ttcttctttg ctaaatcttc tattaatatt ccatagcctc tttttatatc
   129781 aatttttata ttaaaagttt ctaaatattt ctcaatcatc ttcaaatctt tttgtaaagt
   129841 tttatcagat acatttaatt tatctttaaa gtattttata ggtctatatt tattttcgtt
   129901 tagtatcaat ttaagaaatt caatttgcct cgacacaagc atacttagcc ctccctacct
   129961 atgtttatat atttctatgt ttatattaag tactatttta acatatttac taactatgta
   130021 aaattactaa gatacttctg tatcataaaa gaatttatga tacaccttac taaattgata
   130081 taatagataa tataatttca aaataaaaat taaggatatt tagaagtagt taactgattc
   130141 taaatatcct tattattatt ctatatactt gttgttattc cattaattat ttttactatt
   130201 atttataatt taagcaccaa gtaattcaac ttcactattt tcactcctta tagtaggctt
   130261 tgttacccct ataatcaatg ctgttattac tgtaccaatc aatatacaag ctatatatgc
   130321 aactggtgca ctacatgcaa atggtattac aaatattccc ccatgtggtg ccattaaagt
   130381 tatatctaaa ctcatacata ttgccccacc tatacaagaa ccaattatat ttgctggaat
   130441 cattcttaat gggtctgcag ctgcaaacgg tattgcgcct tctgttatga aagatgcccc
   130501 cattatagca gttggtagag atgactttct ttcttcttta gtaaacttat ttttgaatat
   130561 taacatagct aatgatattg ctaatggagg taccattcct cctaccatta atgctgctga
   130621 tggttcaaat atattacttg aaaacatagc caatccaaaa gctgaagctg ttttattaat
   130681 aggtcctccc atatctgatg ccatcatccc tgctaatatt gcacctaata atactttatt
   130741 agttccagac atactttgta accaagattg taaagcttca tttaaccatg atgctggcgt
   130801 attaactaca aagaacatta tagctccact cgtaaatgca atcaaaagtg gacatatcaa
   130861 tacagcattt actcctttta atacatctgg taaattttct gttatcttca ttactcctaa
   130921 agctatatat cctgttgcaa aaccagctac cataccacct ataaaacctg aacctccaat
   130981 aactgccata aaaccagcta tcatagcagg agcaaatcct tgtcttcctg ctattgattt
   131041 agctataaaa ccagcaagta tcggtataaa taacttaaat gctgaatcgc ctccaagttg
   131101 tccaaagaat ccagctatag ggttgtatgt ttcatgagtt gggtctgatg caaatatacc
   131161 aaacataaaa gctatggcta taccaattcc acctatcact acaaatggaa tcatttcaga
   131221 tacaccactc attaagtgct tataaacacc ctttttctct gacccttgaa gcatttcttt
   131281 tgaatcttct aaagtctttc cacctggttt aatttcttta gccattccat tttcagcgtt
   131341 tataattaaa tttttagcta atgaaacatt cttagcatct actactttct tttgtagcac
   131401 tttctttcct ataaatctac tcagttgaac ttctttatca caagctatta ttacgtattc
   131461 agctcttttt atatcttctt tagtcaactt attttctaca cctatagctc catgagtttc
   131521 tattttaact tcatatccaa gttcttgacc tgcttcctct aatgcttttt ttgccataaa
   131581 agtatgagct atacctgttg gacatcctgt tatcccaact ataagacctt tattttgatt
   131641 attactaaaa tctcctgatt ctgcagcttt attattaaat atacttaata tttcgtatgg
   131701 agtttctgca cttagtagat gcttaagaaa attttcttcc attagatatg tagctagttt
   131761 agatataatc ttaagatgtt catctgaacc tgattctgga actgctatca taaaaaatga
   131821 cctaagtttt tgaccatcat tatctgtaat ctctctatct gttcttaaat acatcattac
   131881 aggttgattt actacatttg acttagcatg aggtatagct attaaattac ccatattagt
   131941 tgatgattct ttttcgcgtt tattaatatc agctataaac ttttctttat tatttatata
   132001 atttccatgg tacaaatgat ttgccatata attaattaca tctttttttg tttgtaattg
   132061 tttatctagt acaatacaat cgcttcgtag tattttacct atcataaatt ctcccctcct
   132121 tttaatttgt tacctcataa ttaattttta tttttataaa agcactttaa cttatctata
   132181 gcattgaata gattcatttt aaactctata acttctcttg cagattttat acatggtgga
   132241 tatatagtat ctggctcata taagcttggg ttttgttcta atagttctct gcacttctta
   132301 taatatgccg acttaacatc actcgaaata tttattttac aaactcctag tttaactgct
   132361 tgtgctattt cttcatctgg atttgatgaa ccaccatgaa gaactaaagg tatatctact
   132421 acttctctta tttcttttaa taaatctagt ttaagctctg gtttaaaacc ttttggatat
   132481 ataccatgtg ctgtaccaat tgcaatagct agtgtttcta ctcctgtttt ttcaacaaaa
   132541 tccttagcta attttgaatc tgtatatatt atttcatcag taccaccttc acttgatgtt
   132601 cctgttgttc ctattgttcc aagttctcct tctacggaca catttaatcc ttttgctatt
   132661 tctactattt ccctagatat agctacattc tcttcatatg gtaaatgtga gccatcaatc
   132721 attactgatg taaatccaca tcttattgcc cttaatattt gttctttatt ttccccatga
   132781 tctaagtgta ttaccatagg tactttactc ttatttgctt cttctatgca actagctaca
   132841 aagctatctc ctagaaaact tagctcattt gggtgtattg caagtattac tggtgcattt
   132901 ttttcgttag cactctgtac tactgcttta agtatttgcc cacttcctat attaaatgct
   132961 ggtacagcaa attgattttc ttgtgccact tttagcattt ccttcatatt tattaacata
   133021 ttgtacctcc cgatatttta aattttaggt tgaatttgct tcttgttaat tttgttgttg
   133081 tttatattta aataatatca gggtaatgaa gatcagaaaa taacaatcgt tttccttagt
   133141 gaaaaggaac ttttattata cactctaagt tccttttcac taaataattt ttagaagtct
   133201 gcatcatagt taattatatt tctcatatac atcttctctt tttaagtgtt ttatgcttta
   133261 gccttcttaa ctctttccaa taaacaatta gatagtttag ctataaattt aaagatattc
   133321 gtatcgtagt tagcactata ttggaatcaa aaaaattaaa aagatactag atagcagata
   133381 ccaattatta atacaccata agtcatagat acttctatct taaattcttg catattagtt
   133441 acaatagaaa ttaaatagga ctattataaa aatcgtaagg taagactgac atttattctc
   133501 caactataca aatgaatact aatatagctc cttctaatta aatcatacta tataaatcat
   133561 atatatccca atttttaacc ttacctcttt atatttactt tttaataaaa aaagatattg
   133621 actaaatagt caatatcttt tagtggattt aaatacccac gattttaatc taatttttaa
   133681 tggtttcctt aacataatct tataaatatt aaaatttatc tacctataaa atttctccat
   133741 taaattttat tacattttta taccaatcaa aagatttctt tttatatctt ttaagagtcc
   133801 cacttccatc attattttta tctacatata taaatccata tctttttttc atctctcctg
   133861 ttgtaaatga tactggatct atacatcccc aaacagtata ccctataaca tcaacaccat
   133921 caatttcaat ggcatttttc atttccctta tatgactagc caaatactct attctataat
   133981 catcatctac agtattatct gattttaata catcttctgc tccaaatcca ttttcaacaa
   134041 tgaatatagg aagttcatac ttatcatata gttgattaag gtaaaacctt agacctacag
   134101 ggtctatatt ccatccccaa tcagaaattt ttaagtatgg attttcaact acatcagcct
   134161 ttcctgccga gtcattacct gttgttttca tagttttatc agctgttact acagtagtta
   134221 aataataact acatccaata aaatcaacta ttccttcttt taggattttt ttatcttcct
   134281 ctgtaatatc taaattataa ttttttcttt cccataattt tagtgtatgt cttggataat
   134341 gacctcttac atgtacatca gtaaacataa gttgttctct attagattct acaaatttaa
   134401 tcatatcctc tggattgcaa gaataaggat aacttggcat agctgccacc atacatccaa
   134461 ttttaaactc agggtttatt tcatgaccta tcttcacaac ctttgcactt gctacaaatt
   134521 cataatgaac tgcttgatac ataacttctt ctttgtcttc ctgctcttca tagattattc
   134581 ccgagttagt aaatgcataa ataggatttg tagttatact ttgattattt atttcattga
   134641 aagtcatcca gtacttaact ttatccttgt atctattcat taccacttca cagaagttta
   134701 caaagaaatc tattaatttt ctatttctcc atccaccata gttttttact aaatgataag
   134761 gcatttcaaa atgacttaaa gttattactg gctctatatt gtattttaat aattcatcaa
   134821 ataaatcatc ataaaatttc aatccatctt catttggagt tgattcatcg ccctttggaa
   134881 aaattctagt ccaagcaata cttgtcctaa aacacttata tcccatttca gcaaataatc
   134941 taatatcttc tttataattt tcataaaaat taatggcttc atgattagga taatttaaac
   135001 cctcaattac tccatctgtt atctttcttg aaatagtatg agtacctgca gtcatcacat
   135061 ctgcaatact tattcctttt ccacctttat tatatccacc ttcaacttga tgggcagcaa
   135121 ctgcccctcc ccataaaaat tcttgattag atttcataga aatatctcct ccagtataat
   135181 taataaacaa cttttattac aggcgttcca attttaatat gtttattttc tttaactatt
   135241 acatctgcta aatcatttgt gttagttagt attattggtg taacaatact atacccttca
   135301 ccttctattt tatccttatc gaaagaaaca atcctatctc cttttttaac tttatctcct
   135361 gcattcatat gagtagtata atactttcca tctaacatag tagtgttaag acctacgtgt
   135421 attaatattt ctacaccttt atcagaggta attcctattg catgctttgt aggaaaaata
   135481 gttgttattg ttccatttac aggagacaca acttctccct ttgaaggtat tattgccatg
   135541 ccattaccta tagttcctga tgcaaacact tcatcttcta cttcagataa ctctatttgt
   135601 aagccttcta ttggagataa tatctcctct ataccatcat cttcatcaaa agcaacttct
   135661 tcattacctt cttcacattc ttctttactc aatccaaaga aatatgacaa tactgctcct
   135721 agcactaatg ctgttcctat tcctaatata tatcctagga atggtgtata aactggcatt
   135781 gagaatatat tatgaaatac atatgcatta caagtaacac caaatacacc acatatacca
   135841 ccaccaatac ctcctgcaat agccaatact ggaatcattc ttctgtatct taatataatt
   135901 ccataaatta taggttctgt tactcctgct aaaattcctg taactgctgt tgaacctgct
   135961 aataccttta attctgaatt ttttttagat tttctaacct tcataaataa acctattgca
   136021 atacctattt gagcaaatac tgctgcaaca gctgcacctt ctattgggtc tccacccatt
   136081 gtagccaagt tttgcaaagt aattggtgtg aagccccagt gtagtcctaa tactgctaag
   136141 aatggcatag ctatacctat tgcagctcct gcaattactc tgttaaattc aaataatccc
   136201 ataaaaatat tagatattat atcaccaaca ttagttgcta ttggtccaaa taaaatcaca
   136261 gttaaaggaa ccatgactaa taatgatatc atcggtacta agaataattg taaatccttt
   136321 aatataatct tctttaaaag cttatcaaca tagtaataaa taaatatagc aacaaatata
   136381 gggaatacac caaaagaata atcaattgct gttactggca tcccaaaaaa gttagcacca
   136441 ccttttgctc caattaaagc tgtaaaatta ggatctaaca aagctgctcc tatcactcca
   136501 ccaacatatg gatttgcact aagttttata gctaaggtaa tacctaagaa tattggtaaa
   136561 aagtaaaata cagcatttcc agctgctgat aatatagcat aagtgctact tgtatcagac
   136621 atccatttca tagtagttag tattgtaagc agtgccttaa tcattcctgc tccagctagt
   136681 gcaggtatta atggagaaaa tgcacctgaa attgattcaa atattttaga aactattgaa
   136741 actttttctc cctgttcttc agtattttgt ccttgtaaaa ctgctttttt tataatagtt
   136801 tcaaagtaat cagttacttt atttccaatt accacttggt attgtcctcc actatttact
   136861 acagatagta catccttcat ttttaataac tcttctttgt tagtttttga agtatctttc
   136921 agcttaaaac gtagcctagt tgcacaatga actaaactaa taatattttc ttttcctccg
   136981 acatatttta taatttcttc agactctctt tcaaatttca tacaatctat cctccatttt
   137041 cataatttta tgtataaaaa tagacctaaa tcaatacaat tagatattaa aaactaatta
   137101 taccaactta ggtcatgcct gccaaacagt aacaatccta cactatttac tttatatttg
   137161 ataatctatt taaatgcaat gttaagtaca acaattcatt ttcgctaatt ttccatttat
   137221 acgtcttttc aagaaagttt tttacttttt ttgcacaatt gtaatcactt ttatatttca
   137281 tttttattat atctaacaat gatgtgtcta catttgtatt ctcaccactt aattgccttt
   137341 ttataaaaca tcttaaatga cttataaacc ttgtgtagtc aaaggaatat tcatttattt
   137401 cgattccata gtgatacttt atgatatcta atacattatc aattatctta gttaacaata
   137461 aagtttcttg catatctttt gtttctaact gagcatttgc aaagtgtatc gtaataaatg
   137521 ctatttcaga atcaggaata tttttatcta atttttttct taaatattct acagctttct
   137581 tactaaaatt atattcatta ggatatattt gtcttatttc ccattgaagc gggctttgaa
   137641 atactaatcc ttcatccatt ctttttaaca tataacttat atgttctgat aatgtgatta
   137701 atatactatc attaagatta tcacccaatt cttctcttcc catttgaata atttcactta
   137761 caagctcaac atcttttaaa ggtatcctat ctagtagtga atgtaattca cttaatgatt
   137821 cctcattatt gaatataaat ttcttttcaa ttttatctat ttcaactaaa tctttagtaa
   137881 atttattaaa tccaattcct tttcccatta atattacttc ttgtcctgaa ttatctctgg
   137941 caaatacaac attattatta aatactttct ttataaccat aaactacctc cactgtaaac
   138001 aaaaagagac ctaaaaaaga ctaataatac tttaagcatt tactagaatt tttaggtcac
   138061 gcctgattac atctatctca gtaacgatcc gtttatttat ctgtatgata actttatttt
   138121 cattataaaa taataactgt acttagtcaa tatataattt catgtatatc tctactagat
   138181 tattgtcata agtattcact cattctactt ttttatatga tttatataat ctaaacatgc
   138241 taaaataagt tttgaagtta tttcataaca aaattaaggt catatatttt ttattatata
   138301 tactcgatta tttatccata tataaggaaa tcctttattt tgtaactaca ataactgcct
   138361 aagttttgat tttcttttat cttttacttc tccttattaa aaaataattc ttttactgtt
   138421 gtatctaagg ctctaaacag tttaatcatc aaatcattgt ttggattatt aaccttacct
   138481 aacttactat atagcttttt aactgtatat ctttaataga ccttttggta tgctaatcca
   138541 ttttataaca ctaattcttg aatcaagcat atattaccct tacaaagcat atcttatacc
   138601 ctctgtagag ttatgatagt tgatgaacct gaagaaatta cccttacaag acatatctga
   138661 tacaacctca cttattagtt tatatgtttc agaagtatat aaataacaca tacttacttc
   138721 caaattctta actgttttct tagaaaattc taatatgatt tccttacata gcgattataa
   138781 cagtgtctta ttagatttca taaaattata catcctcttt acatttaaac tttaaatttt
   138841 tatctattgt ttattaatta actgtatatt cactattttt tatcatttat aatactcttc
   138901 ttattatctt aaaacaatta taatctaacc ttaatcacat attatataaa tatttttaat
   138961 aaacttaata attaaataac tatatttcat tatccatctt ataaatgttt ataaactttc
   139021 cactattctt cttcaataaa ttcaaacaaa ttttctactg tagtatcgaa tactttagcg
   139081 atatccatag ctaacttcaa agaaggatta tatttcccat tttctaagtg tacaatagtc
   139141 tcacgtctta ccccaaccaa tttagcaagt tcattttgcg tcataaggag tttttctctg
   139201 tattctttaa tttttgtttt catcaatatt gccacttagt tacatatccc ccttttatca
   139261 aagtatatat acaacactaa tttagataaa gactgtataa ataaaactgc aatgaggatt
   139321 atacctgtat ctaggtttga tatatttata ttacttgtat aaggtgttgc aaagaaaata
   139381 gatattatta ctatagaata tatcattatt tttattgcaa tcttattaac ctttgatagt
   139441 ataaattcag atgattcatc aactaaatca ttatattttt tattataaat tgaataacat
   139501 ccaaaaacta ttaaccaact caaccctgga agagaagcag tgcttggacc tttaaaaata
   139561 tatttagtag ctaatacagc tataaaaaaa taagttatta caagtaattc caagatgagc
   139621 tttgatctta caccagtttc tgatttagac atataaaatc actccttaaa agttatatat
   139681 tctctatatt ttttaatttt tgttttcata aatattatta cttagttaca tattcccttt
   139741 ttatcaaaat atatatacaa aattaatttt gacaaagatt gtatgaataa aactgctaag
   139801 agcattatac ctatatccaa atttgatatg tccaaagctc ttgtatgatt aactgaaaag
   139861 agaacagcta ttacaaacat agagtataac attatttttg atgcaatctg atcaaccttt
   139921 aacaacataa gttttgatgc ctcatcaact aaatcattat attttttatt atacatgaga
   139981 ttgcacaccc aaaaagctaa taaaattata aaagtaaacc aaataccttc tcctttaaaa
   140041 ataaactttt gtaataacaa gtctataaaa aaataggata gcatcattaa ctctgaaaca
   140101 agatttgcct taacaccaag ctctgattta gacatataaa atcacccctt aaaagttata
   140161 tatttataac accttatgtt ataaatatat aacttttcca aataaattgc aatagaatat
   140221 tgaaaatatt caataatatc ttcataaata tattttataa aagattttat aataaacatt
   140281 acaatacagt actaaattag tttatttcat ctatcatctc aatcatatca tttactaact
   140341 attattctaa tgagcatata acattgaaat ttataattat acaacctaaa tgcctcccaa
   140401 tgtaccctca aaaacatcat ttcctgtaac tgaagtataa ttggtatatt ttatcactga
   140461 aataaaaaaa cactagtcaa taaagactag tattttcaag tattttatca ttcttttttt
   140521 aattattgga gacgaatcat cagaataatg cccataattt atctatatgc aaattctaaa
   140581 tttaaaataa agtttcagat gaatttacta ttctatgcta tgatacaaca gaaaaaactg
   140641 aaatctatga gtggtagctt catataatcc tagttcctac agtaatcaaa actgaggttt
   140701 attctatatg taactaatga taaattttat tataggagtt attagctcta tttgtgttac
   140761 tataagtagt aattatatat atgataattt tttaacactt ttctgttggc tatatagaaa
   140821 gtggtttaga atttaaattt aaataaaatt taaattcacc aaaaagaaat ctatattaga
   140881 aaccactact ctattccacc agattgtaat tttttgttct ttatatcaca atgctatacc
   140941 atattaaatt gaaaaataaa ttttaaattt atttgttaca attcattaat tcaaaaaaat
   141001 attttgagtc atgagttttg taaagattta gccatgaatt taatgcttct gattcaaaaa
   141061 catctaaaag tttcaatact tgaaacgtaa attccaacgg agcgattcct gaagccgtaa
   141121 ctaaattttc atcactaact acagattccg ttttataata tttttctcca gagtaatttg
   141181 gtattaccat tttaagaaac tctaagtcat tacttgtatg atttctaaca tctaatagcc
   141241 cttttttagc taggcctaat gtagctccac atatggctgc aactatagaa tcttgtatta
   141301 aagcttcttt aactttttct aatattatct catgattcat ggataaccaa gtatttcccc
   141361 ctggcaaaat taataaatcc ttactttcca tattaaactc atcaactgta atttcaggta
   141421 aaacttttaa cccacccatt gttataatag gatttttatc aattcctaca gtaattactt
   141481 ttagtggctt taatcctttt ttaaaatatc ttcctgtatt taattcagca gttaaatatg
   141541 ccacttccca atctgacata gtatcaaata catacatata tacttttcta tttttcatct
   141601 tttttactcc ttatgtaatt aatttatata tctaattata aaataactta actgacatat
   141661 tcagtcagtt aagctattaa atttgataat aatcaattaa ttctagtaaa tcttcaatta
   141721 ttttcttcct aaggcttagt ggttcaatta cttgtattgt ctttctataa ggtaaaagta
   141781 tatttggtat gtacttgcat attacttcct cttcgagcat aaatattatt ttattaggtg
   141841 ttctttcttt caagtagtgc cctaaaaacc aatgttggct taaactatct aaagaatcta
   141901 tactcccttc tacaactaat tgaattatat tttgttcatc ttttatttca ggtataattc
   141961 cttttataaa aaattcactt gctgaaaatt ctgtcggtct gttaaatgta tttgatgttt
   142021 ctatgatttc actaatccta tccactctga aactacgtac ctcatttctc atattacaaa
   142081 atgcaactac gtaccaatta ttattccagt gaacaattcc atatggattt ataattctat
   142141 attttgattt tgctttacga cctgcatgat agttgatttc tacagatagc tcctttaata
   142201 tactattctc caatttttta agtactgatt ctatagacac tttcccaatt ggttttatta
   142261 cttcaagggc tcttaagtgg tttgttaaaa tatcttcttg gttttgattt gaatacattt
   142321 ttaactttaa tatcgattta tctaatgctt cgtctaagaa gtatccttct tttttagcaa
   142381 atagagctgc atgaagtaga gatttttgct cttctatatc aaaaaaaaga ggtgctttag
   142441 taaaattatt taaaaggcta tacccaccat tatgacctgt atctgaaatt ataggtactc
   142501 cactcgcaga aagtacatca atatatcggt acactgttct tatatttatt tctaattttt
   142561 cagctatctg ttttgctgta atttttttgt cagagtttaa catccacagt atagacatca
   142621 tattgtcaat tttagccatg tagtttcacc tctttctatt tgttatataa agttattata
   142681 taactttttg attgattttt tacaaaaaaa cattagtaaa ctgctaataa tttatactaa
   142741 gatttatttc aaatatttat agatagtctt tttctatagt taagttatcc attaaattac
   142801 atagtagtat atccatttta gttgatatat tttcagctac ctcccttgaa tattattaca
   142861 ataagtctaa atcttctttc ttccataaat atattatgag gaaagactat catctttaat
   142921 ggtttaatag tataaaagat attaatttaa aaaaatctat ttttatatca gatgggtatt
   142981 gttttttata aaactgaaaa aatcacctaa tagaatctat gattttttaa cataacctcc
   143041 ataaattagt accaattatc acttcaaatt caaattttta tctgaagaat atacaatcat
   143101 atttccatac tcaacataat attgagtgtt tggcttgtat ttacaaatta ttattctaac
   143161 aaaaacaact atacatagat taaaatcacc ttctaaacat aattattaaa atttaattaa
   143221 tgatatcaat tccattaatc tcttttaata aaaaattctc ttttctatat gaaaattatt
   143281 tcaaaacttt taagttaaat acaaaaatga ctataaatag atttttattt acacaaatct
   143341 atttatagtc actatagttt atccaataaa ataataaaat aaatatgtac acaataaatg
   143401 ttatttacgt cttaagtatt tatttgttag atttttaatt aaaaaaaaca agctaatgaa
   143461 cattaatgct aaatctagca ttatattact ttgatctcct gtttgtacat tttgacctac
   143521 attactatct aaactttcat ctgtatctat atttatatct ggttttccat tcccatctgt
   143581 atctatattt atatccggct ttccatcccc atctgtatct atatttatat ccggttttcc
   143641 atctccatct atatctatat ttatatctgg ttttccatct ccatctatat ctatatttat
   143701 atctggtttt ccatctccat ctatatctat atttatatct ggttttccat ctccatctgt
   143761 atctatattt atatctggtt ttccatctcc atctatatct atatttatat tcggttttcc
   143821 atccccatct gtatctatat ctggtttgct atttcctcca ttatctgggt ctggtttact
   143881 atttccaccg ttatctggat ccggtttgct atttcctcca ttatctggat ctggtttacc
   143941 attgccaccg ttatctggat ctggtttgct atttcctccg ttatctggat ccggtttgct
   144001 atttcctcca ttacctgaat ccggtttgct atttcctcca ttacctgaat ctggtttgct
   144061 atttcctcca ttacctgaat ccggtttgct atttcctcca ttacctgaat ctggtttgct
   144121 atttcctcca ttatctggat ccggcttgct atttcctcca ttatctggat ctggcttatt
   144181 tagatttgga ttacctgtat cataacctcc tgagccagta tctacatttt tatcaggctt
   144241 ccaataatca tctactccat cattatctgt atctattgct ggacgattat aatctgtatc
   144301 agggtttcca tctccattgg tatctatatt tttatcaggt ttccaaatac catctccatt
   144361 tccaccttct gtactaggct tccattcacc tgtattatca gtatctatgt taatatctgg
   144421 cttccaatca ccactcgtat ctatattgat atctggcctt ccatcaccat cagtgtctat
   144481 atttatatcc ggtattccat ccccatctac atctacattt gtcatatcta actttaactt
   144541 cttttcatcc tcactacctt caatgtaatt tatatcatct ccaatatatt ttacagtaat
   144601 agtttgttca gtagtaaaaa tatgatgatt gctatctaaa ggtctccatt caatagatgc
   144661 agtactataa ttatgactct cactaccctt attatgagtt tttaattcta ctggatcttt
   144721 atattccttt ctattaatat agaattgtac gtaacctctt ggagaggcac aatctggtcc
   144781 ttctttctta tctggtgaaa tagtaacatt taatgtaaac gtatctgttg gtttaaaaac
   144841 atcagtttta gctttagact cttctacaac taatgaagtt tctgtatcag caggaataat
   144901 ttctgcctta taatatgctc tatgccccca ataagcttca ttaaaaggat atacatttga
   144961 aaactgtgtt gatgtaatgc ttaattgata ttttccagca tcaacttgct ttgtaaggtc
   145021 atcacttcct aaatttgtat ctggttccat tgtttcctca tttaaacgtt gagaactaat
   145081 agtcataaat tttttatctg tgagtttttc acctttagga gtaattattg gaataccccc
   145141 atcttttaat atccaatcta aaaataattt ttctacatct tcttcaaatg gtaatccatc
   145201 atatctttta ataatcaaat atggtggagt atcatcaata gtaaattctt catattgctt
   145261 taaaaattga gaacctgaac ctatatcttt aacataaaaa tcatctggtt ttatatttcc
   145321 tccagtaatt ttatctataa caactaaatt aacagatact tcagatccct taaattgatc
   145381 agaaaaccat aagtaaagaa ccccttgatc atctgtataa ctaggtgctc cataaggata
   145441 aatttttcca tcaattagca ttttaaaatc atcaactaat gtagtactaa ctttatcttg
   145501 tcctaaatac tttaaagata ttttattcat aaaaactttt gttttctttt ctaaatcacc
   145561 gtatgcaact gctccaccta aacttttgaa tgttgttgct tttaatgaac cacctgttac
   145621 tataacatct cctgttgtag cacttaggtc aaaaatccaa tctcccactc ctgtcatata
   145681 aggtaaaatc gttcctccag ttacaagtat acgatatcct ctatttgttc ctggattaac
   145741 acatccatcc ccaaatgcac taccatgtgc acctccatat gaataggaaa gtccaccatt
   145801 aattgtaata tttccactat aaccagaacc tgtgctagga tctactactg agggacttaa
   145861 tgcattcttt gttgttgtat agtatcctcc acctattcca gctccatggt atgcaccttt
   145921 agcagttata gtaccaccat tgattgtgat atctccacca ctaccattac cgcctccacc
   145981 tattccagct ccatatcctg tattacgact cgattcttga cctatagcag ttatagcacc
   146041 accattaata ataatatttc ctccactttc agtatttcca ccgccaatac ctgcagaata
   146101 ataatttcca acaactttta aacttcctct attattacta tctagtagtg taaggcgatc
   146161 tccttttttt aacttgtctc cattttctag agttacatct ctaggaattt ttccaccctc
   146221 aggaactata aactctcctt caatatctct atttacaaca gaatcatcaa tagttagagt
   146281 agtacctttt cctgctctca tacctggata atatacatca cctgactcta gcttgttttc
   146341 actaccatct tgtaatataa catgtgcata tgcaccacca tctttatctg gtgttaaagt
   146401 aaatgggcta ttagatgcag ttttaatatt tactccatca aatattaatt cagcttttac
   146461 atctttaggt ataacaatcc tatgtgttgt tggagtattt ggattattat tttgaattgt
   146521 catttgtttt ccactaagaa tagttaaaac gccacttgca aatttaaaat cgacatttat
   146581 ttctccacca ctaattttaa agtctcctac agatgtagga tcttctgcag tggcttcttc
   146641 cacaactaat gcattcatat cttcttctgc atttcctgca ttagaatctt cttctgcatt
   146701 tcctgcatta gcatcttctt ctgcatttcc tgcattagca tctccttctg catttcctgc
   146761 attagaatct tcttctgcat ttcctgcatt agcatcccct cctgcatttc ctgcattagc
   146821 atcccctcct gcatttcctg cattagcatc ccctcctgca tttcctgcat tagcatcccc
   146881 tcctgcattt cctgcattag tatctccttc tgcatttcct gcattagtat ctccttctgc
   146941 atttcctgca ttagtatctc cttctgcatt tcctgcatta gtactttctt ctatagtatc
   147001 tgcgaaagta tttgacgcat taaatgatgc tactgatcca agtcccattg agatacttaa
   147061 aatcattgat agtgctttct ttttacattt ttgttgcata aattccccct ccccttaata
   147121 atttttaata tacactgtat acatccttat atacactcta ataattctta atatacactg
   147181 tatacatcct tatatgcact ctaataattt ttaatatata cttaaaactt atatttgtca
   147241 atgaatatac tgtttttttc aaccttatat attataagta ttcattattt gctaaataac
   147301 tacaataaaa attttaatta tataaaattt atttaatttt ttatataata atactaaggg
   147361 gtaattaatt gaaaaactag taaaaatatt aataaatatt atttgcatta ttgcgctaac
   147421 tttctctagc ctttcgattt acataaaatt atctgaatat aaaaaagctg atgaagtata
   147481 tacggaactc agagaaaaca ctatcaataa tagcaaacat caagaacttt atgataaaaa
   147541 taatgattat agattctggc ttaaaataaa caacgtaaat ataaactatc ctgtagtaca
   147601 aggatataac aatgatttct acctaactca tgatttttat aaaaattatc ttcctttagg
   147661 tagtattttc atggattata gaaataattt tgaaaatgat aagagtttaa tagtctatgg
   147721 tcattatatg aaaaataaaa ctatgtttgg tcaactagaa aactatactg atgaagtatt
   147781 tttcaaagaa aataacttag tagaaataaa ttataaagta caaacttata cttatgaaat
   147841 tttttcagta tatactgctg acttaattaa cagagattat ttaagtatac actttaataa
   147901 taatgatgag tttaaatatt ctttgaatta tataacctaa aaatcagtac acaaatctga
   147961 tataaaggta gatatttcag ataaaattat aactttgtat acttgtaact atgaatttaa
   148021 agatgctctt actatagttc atgctaaatt aatttcaaaa aagagaccta taagtaggtt
   148081 tgtgtaaatg cagacttatc tacagtcttt tttgaacgta aaattggtaa gtatggaata
   148141 atatttatat taaacttttg taggcaaaga aatgaaaaat caaagagaaa taattattac
   148201 agatttagat taccaagctg aattaagaaa gtgtaaaact atggaggatg tagttggtga
   148261 agatagtata taatagctta acttataaat tatcttggtg atattaatga agtttcaaag
   148321 tatatattat ttattgatat aaataaaatt aaatctgttt ctaatagatg tacctttgtt
   148381 tggagacaaa ctattgaaga aatataacta aaatgttgaa gtagctacct gactttattt
   148441 tgaaatgcga acaagatttt ggcattaaga taatttagaa agaatcactg gtacacaagg
   148501 atgtgaactt agaatgaata gaagtattca ggcataagga gctttcaccc aaataaaaca
   148561 tagtatgaac tttaaaagaa ttctaatcaa aggcaatcaa aatattcttt cagagtttat
   148621 acctgtagtg ttagcctata gtatttctaa gtttcacaaa taagataatc attaataaat
   148681 gtaggatgta tattcatcct ctcaaaaata ttttttaatc ttacactttg taaattattc
   148741 tattttaaaa ttgtattttt atacctttat ttcttatgac cgttttcaag ctcaaatttt
   148801 gcataaatat aaattaatga aaagcaagta aaaaaagaac tgtcgcacag caatttaaaa
   148861 ttactcattc gacagtcctt atttcgtgga ttaatgttgg ataagaatca caagaataat
   148921 acccactatt ttatttgaac tatccatcta gtgcttcaaa cacatctcta agatactcat
   148981 ttggttcatc attaaataaa tttaatatct tttctgctac tactcgacct aataaaggtg
   149041 gtactgcatt tcctatctgt tgatatacag aatcttttgt acctaaaaac ttataactat
   149101 cagggaatga ctgcaatcta gccgcctctc ttgcgctaac agctctgttt ttaataggat
   149161 gtatccacat agattttctt acatttacaa cagtatctga tggcttatca tatactagtc
   149221 ttttataaat agtattttga gttctttctg gatcagcata agttcctttt aactcatctg
   149281 gcaaagaatg aaaattattt ccttgattta tatattcaaa tctttttagt gcgatatttc
   149341 ttgtatctgt acatacatga ttgtatattt tattgctatc caatattatc tttctataaa
   149401 aatctttttc aatattatta ctattttttt caaaacaata atccatacta cctttagaag
   149461 cctcatattc agctaaatcg cctattgcat ctcttactgt aacataattt tctccaacta
   149521 taggcttagg agtttctatc tttttatttt ttaagaagtc tttttttgct cctatcaata
   149581 caaatctttc tctattttga ggtactccat aatcaattga atttagtgca cttccattta
   149641 atacatatcc tagatactca aaggatgcat ttatataatc tattataatg taagtatcca
   149701 ttttagctat aattttatta tcatcaagtg tattttcgaa aattacagat tcagatttta
   149761 actcatatat tcctaaaaat aaattttgaa tatccaagaa taagttcaaa taaaatattt
   149821 gttcatctga taaatttcta ttatataaca tattttctaa tatatttttt actttattta
   149881 ttaattctaa ataccatttt ggcatttttc cccttgtttc caatttttct atggtagatt
   149941 ttactttctt ataattagat attttattta aataatcaca tatatccttt tttttcttaa
   150001 taattatttt caaatttttt aagtctatat ttgatataat atatgattca atatcttcta
   150061 tactaataat attaaataat tcatttatat actcagttct atcatataaa acactatctt
   150121 tattataaat atttaatttt aaattattta ttatatgatt tttatctttt ttagtcaaat
   150181 aaaatgaatg cttatttgaa gatatagttt tgacattttc cattacaaat acatttggct
   150241 ttaatttatc aatagcatca acatatagct taactaattc attatttcca tttataattt
   150301 ttcttttttg tctattagca ttagaaaaac cttgacatgg cggtcctcct ataacaacat
   150361 ctatcttatc gacactgttt aatatatctt gaaaatctaa tcttttaata tcacaataac
   150421 gcttaacact cggatgattt tcaaggtatg tttttgctgc gttatcattt ttttctacaa
   150481 aagccaccat attaaatttt ttagtcattt caaatcctaa gctcaaacca cctgcacctg
   150541 caaaaagatc tataacatta tacattctga catacctcac attaactttt attgcagcat
   150601 atcatatttt ttttcacatg tcaatttttg aataatcatt tcaaatttct tatacttgta
   150661 atagctttta ataaattcta atatttttac ttacacatta tttttcttat ttatgtcttc
   150721 tggataatct attcaaataa ataacataat atatttttta tttatttatc aatctttttt
   150781 tatattatat accatatatt attttttagt aatataatta taatatagaa taaaaactat
   150841 tctaataaac aatagtaact actaaaggag atttaaatgt taactacaaa tatccattat
   150901 attcttgata atgatatatg tgaaatttat tttaataaac aaaggctaac aaattctaag
   150961 tattatcaag ataatattaa tgtattaaat tatattataa atgaaaaaaa taataactta
   151021 attatcaatt ataatgacaa atacatatat gctatttatt tgttgaatat agctataaac
   151081 tcatacttaa ataatacatt aaacccaaat aatcacattc ttacaaaact cgataaaggt
   151141 atgcccctgc tctacaaggg tcaaatagtt atatttaaaa atataaataa tacacacata
   151201 actttaggac ataaaaataa aacggataca acacttatac ctattgactc ggcttatatg
   151261 cttataacct ataatggtca tttagaagtc aattctatgg gcaaaactcc agcatctaag
   151321 acttttcaaa caaagaatgt tctatcatct ttaggttttt cagacttaaa aaatatgact
   151381 ggagtaataa atgattctac actgattata ttgccttgta aagatgatat atctgactta
   151441 gttagtaata ttaaaataaa agatattaat aatacttata agtttactga actatttcca
   151501 tgttcatata tttcatcaac tggtgccgaa actgattatc ctggaaatca cgctaagcaa
   151561 atacctttac ttaaatttac aactaatatt tctagtgcat ttgaaattat taaatctgat
   151621 aagtctataa aaaatgtatt tataataggt gattatccaa tttataagca tataaatgat
   151681 tttgaaagaa ttttaaatag aaaaaggata gaaagtgtaa atattgtaac ctcaaattca
   151741 aatataagca atatattaga tttaccaaat atagataatc taaatatata ctcttggtct
   151801 aaagatgttc tgttaaccta tagccaagat tttgaaaata cctctacttt tcagaaatta
   151861 tggctagata aacttataaa taaaaatata tgtactactt ctgttgattc taatatctct
   151921 gacttgatac atcaggctag aaaatcactt tattacatat ctaagtatga ttttgatatt
   151981 tccataaaaa actcacttat gatgtgtagt tactctcttc ttaaaatctt agaaaataca
   152041 ccttttaacc tagatttttt agaagaaact ataaagcttt taaatttaaa tatagcaact
   152101 ccttcagcga agctagaaaa tataaaatat ttaatttcaa gtactagccc agatttagaa
   152161 ttaagtgcat tatttgatga tgttatagtc aaatttgaaa gaattataaa tgaattatct
   152221 gataataata ccaaattcaa tacactaaat aaattagtat cttcatataa atacaaaaca
   152281 tttacaccaa atacacctgt tatattgcta caaaaacaat atgaagctat tatacttaaa
   152341 aatttattaa aatctagaaa tataaattta caagttattt ctgctgaaaa atttaaagat
   152401 tcaaaaacaa taaaaaatct tattatgttt ggattctatg atttgaaata tttagatatt
   152461 ttaaatagtg atttgattat aaatattaca ctgtatttat ataatagtga attatccaaa
   152521 tataattact atatgaatca aataaattct gcaagaaata aaattgaaaa aaataataaa
   152581 atatataact tacttgatat aaaacctttt aaaccaactt atgaaaccaa taaattagaa
   152641 gcttattcta ccgatagtcc tatttctgat gatgattcta tggatgaata tatatctaat
   152701 tataaatttg atataaattt aaatgaaatt atattatctc tatctataaa tcaagggatt
   152761 tacaactcta aaaaagaaca tgttacatca ttcatgattt ctgataataa tgagtatata
   152821 ttctgtacaa aaaaggcaat agcctattca atagattggg ataaaaaaag tgttaggaaa
   152881 aagaaacttt cagaggctaa agttaatgac tggtttttat ttgttgatga ttacttaaat
   152941 gaagagggtg aattagttat taatgttata caaaagctat tagaacttaa tttattgcca
   153001 tctcattatc ttgatgatta taaattaact aattcatgga aatcagaact taaaaactat
   153061 atatcttata gtaaatataa ttataatgat gtatcaaaca gtttagctgt tttaggtgaa
   153121 aagattaatc ctataacaat caaaaactgg gtaacaaata aaagattaat aggtcctata
   153181 tatttaaaaa ctttcgaaaa gatatttaaa gttatagatt ctaaattaga tcataccgag
   153241 gtatatgatg ctactaaaag tatacgctct ttgcacacta aaataaaaaa atctatagat
   153301 acatttgtat ctgataattt ctttagcagt aaatcagata taattaaaga tgaagtgtct
   153361 gcagttgttt taagtatgct tgggaataca aatgattatg ttacacctgt acaaatacga
   153421 gaaatacaca gttgtgataa gtatctgtca ccccaccttg ttaacaaagt tttagactta
   153481 tatagtgttt attaaataaa taggaggtaa atatgaattg tagtgaacta agagataaaa
   153541 ccctagatct tgtaagaaaa gaacttcttg gacctggttc ggaagatctt tgtgaaaata
   153601 taaaatatga aataataaca gatagtccaa tagagcgtta ttcaacaggt attttatatc
   153661 cacttaataa caatattgat gtaagtaata catctgaata tgatggtgaa gataatgtat
   153721 ttacatcaga tgatacacaa aatgaactag atagagctat aagtatgtct aatgaaactt
   153781 taccttcttc tatgggtatg acttttttcc taaaaaaaga tgcagaagta ataaatttca
   153841 gggtaaatta tgctacttat agaaatgctt tatatacaga ctgtcatgtt aaatatactg
   153901 gtgacgactt ctattctagc aatacaatta atgaatatgt agaacttagg ggatcattcc
   153961 tatatcttaa gcaaaaacta acatctgaga aggtttataa tttactaaaa aagcatgatt
   154021 tacttgataa tgctgaagct aaatttgttt tatacaagtt agctaaccaa tgccctgatg
   154081 atgagaataa gactggtggt tatgttcgtg ttccacatga aaacttaata gtatcaatag
   154141 atatggataa aaactatatt aaaaaaccta tatctaaaga tttagatata gttttatcta
   154201 aaagaattta ttcaaatgac tttgttagta ttacttgtat gctggttaat agtcaatctg
   154261 ggcctaagaa atataataat actattttcc agcctgaact aatggtatta gctgaagata
   154321 acaatgattt agagtttata gatattttta cagctggatc agtaaatact tttaaaaagt
   154381 tagattctga ggaaatatct ttagacttac tttaccgaaa taaaaaaact tttgctactg
   154441 gtcatggtgt agctatagat caagatattc aaaatgatgc tttaataaaa ctttgtactg
   154501 agtttattcc tcattttgaa gtacctaaat tggactttaa tgtagatgaa ttaagtgatg
   154561 tttctagaga attactgtct atgaaaaatt tatcagatat ctctgatctt agtaaagata
   154621 agaaaatata ttttctttat aagtttgttg atgcttatga tatttggata gatgatctag
   154681 aagaagattc aaaagatctt agtgatgttt ttaaagatgt agcatatgag catataaaaa
   154741 actgcagaga tactaagtct agaatgctag aaggtataaa tttaattaag tctaatgatg
   154801 aagtatacag agcattttct ctaatgaata gagctatact tatgcaaaga tgtcattcta
   154861 tacatattac ggatagactc cctggatcta ataaccttga ctatatagat tactcaaatg
   154921 ataattctgc ttggagacca ttccagcttg cttatatact tacatgttta tcttcgatag
   154981 aaaatcctga ctctaaacat agagatttag ttgaccttct ttggatccct actggtggag
   155041 gtaaaacgga ggcctactta ggtctatctg cttttactat cttcttaaga agaataagaa
   155101 acaaagaaaa tggtaacggt acagctatca taatgagata tacactaagg ctattggctg
   155161 cacaacaatt cataagagca agtatattaa tttgtgcctg tgaaattatt agaaaagaaa
   155221 ataagtctga acttgggaaa aaagagattt ctattggttt gtggattggg agtgatcaaa
   155281 ctccaaactt taatgatgag gcagaagaaa tgcttaataa cttaacaggt aataacatta
   155341 agtttagatc tagtataaat agtgaatatg agttagataa tttaaaatca aaatataata
   155401 aattccaatt actaaaatgt ccttggtgtg gaacaaaact tgttaaagaa tgggataaaa
   155461 cttctaaaaa agctgttggt gattggggct atagaattaa atctagacct aagaaattct
   155521 acttatgctg tcctgaagaa gattgttcat ttgaagatat gttacctata caagttgtag
   155581 atgaggagat ttataataac cctccaacac ttttatttgg tacagttgat aaatttgcaa
   155641 tgataacttg gactacagaa gtagctagtc tttttgcttt agatgatgat aatagcaact
   155701 tatctcctga gttaataatt caagatgagc ttcatcttat ttctggacct ttaggtacta
   155761 tggtaggttt atatgaaact gcacttgatg ctatgtgtag ctataagggt ataaaaccta
   155821 agattatagc ttctactgct actataagaa aagcacaaaa tcaagttaaa aatctatata
   155881 atcgtaatgt agctcagttt ccacctccag gattaacatc tagtaactct ttctttgtta
   155941 aagagatgcc tttaagtaaa aaacgtggcc gactatatgt aggtgttatt ccatctggaa
   156001 aaactcaagt tactgtagag gttagactta tgtcagcatt actccaaaga cttaaaatga
   156061 tggagaatgt agagttgaat ttattggata aatattggac actagtatct tattttaata
   156121 gtatcagaga attaggtaag tgtagcacac ttttaaatga cgatataaaa gacaacatgg
   156181 aaagattatg taaaagagtc tcagcccacc cttatcaatc attaaggaac ctaaatgaac
   156241 aaagagagct tactagtaga cttacttcta ctaagataaa tacaacttta gatgaactat
   156301 ctaatactct tacttctaat aatttaactg tcgatactct attagctagt aatatgattt
   156361 cagttggtgt tgatgttgat agattaaatt taatggtagt agttggtcag cctaagttaa
   156421 catctgaata catacaagct agcagtagag ttggtagaag taatgaagga cttatattta
   156481 cattatataa tcctacaaaa acaagagata gatctcatta tgaacagttc tttagttatc
   156541 atcaatcatt ctataaattt gttgaaccta ctagtattac acctttctct gaaccagcta
   156601 gagaaagagg catgcatgca gtattaataa gtatgattag acatatttta ggacttcaag
   156661 ctaatgatct tgcaagtcga ttttcaaaaa atatggatgg tgtagaagat ttaaaaaact
   156721 tcataataga tagatctatc gatatattta gagaaaataa tcaaaatgct gatgataata
   156781 tagtaaatga atttaaatct gagatttcat ctgaattaga tattataatg gatttatggc
   156841 atgataaagc tcaaatatct gataaagata atttattgca ttattataag cgccctagta
   156901 aatttgataa taaaatatat aataatcttt taattcctta tgataaggat gttattacaa
   156961 atgaaaaaca aacattaaat tctatgagaa atgttgataa acaatgtact gttgaaatta
   157021 tagaattgga ggaaaattaa tatgtctata aaattagatg ataaaactca taatttaaga
   157081 ataaatcaag ctacaagtgt ttttggacca ggagctatgc tagattttat tgatcaaaca
   157141 ttaatgactg ctcatccaaa ttattggact aatacaatta aaatacaaga tgataggctt
   157201 caggctacat tgagggttaa tgaactaaga acacctccaa ctatagatga tagatcttct
   157261 gttccttttg ttaggtttcc tagatggtac ttttgtccaa aatgtagaaa atttatgcct
   157321 atagaagatt gggagaaact ttataaaaat gctcataaag ataaacctat gaaaatacct
   157381 atttgcctta cttgtagcac aaaaaagtct actaaacaat tagtacctac tggtataatt
   157441 actatttgtg aacatggtca tattgatgat tttccatggg taaaatgggt tcattttaga
   157501 aataaatctg gaagaaaaga aatttgtgaa aatcctcaaa tattaatgaa gactggaaaa
   157561 agtaacctag gattagaagg tatagaactt gaatgtagct gtggagctaa agctaatatg
   157621 aagggcgcat ttatgcgttt aaaatcttct aaatctaatg attatggtgt acctagtgaa
   157681 tataaggaaa tgtttaaatg ctctggtaat tcgccttggt ataataaaaa agtaaataaa
   157741 tgcactaaat attcatttgc ttctcaaaga ggtgcctcta atgtatatta tcctaagata
   157801 gaaagttcaa ttattatacc accatactct gatactctta attctaaagt gctatctagt
   157861 aaaggttatg atacatttaa gaaattctta gatcgtgcta ttaaaaagaa taagttagaa
   157921 cgctttatgg atgaggattt tgaggacttt gccagtgata ttgctaaaga aacaggtttt
   157981 gatactgata aagtatccat agttttgaaa gatttattgc cttttgaaga ttcttcacca
   158041 tcaacaacaa ctagaaatca atatagagaa gaagaatatg aggctttaat tggaaatata
   158101 gatgctaaat ctaaaaaaac taatgacttt acaatagaag aacaaaatct atctgattat
   158161 gatattccaa acttcagtaa aatagtgtta gtaaaaagac ttagagaagt aagggcatta
   158221 actgggttta gtagagtcaa tccacctgat aataatatat ttggtgaaga agatatagat
   158281 gatagctgta atgatactaa ggttataagt ttaagatcta gagattgtaa aaaatctttt
   158341 tatcctgcat ctgaggttag aggtgaaggt attttcatag agataaataa tgatatggta
   158401 aaaagctgga tttcatctaa tcctaaaata caggataatg catctatttt aaattctaga
   158461 tataataaag atattaatgt taatgacaaa gcttatagaa aaattacacc taaattctta
   158521 ttactacata ctttagctca tttaattata agagaactta gttttgtttg tggatatgct
   158581 acctcttcac ttagggaacg tatatattgt aataattccg aaaatgaaaa agttatgtct
   158641 ggaattttag tttacactgc aagtggtgac tctgaaggta ctttaggagg attagttagg
   158701 caaggtatgc atgattcatt accatctata ttaaatagtg ctcttaatcg tgctctttgg
   158761 tgttctaatg acccaatatg tattgatagt actggtcaag gtagaaattc tttaaatcta
   158821 ggagcatgcc attcatgtac tttattgcct gaaactagct gtgaggagta taatttatta
   158881 cttgatagaa gcatgttaat tggtgatatg gataatagag atattgggtt ctttaaaaat
   158941 ctaattttaa tttagtaata actaattttt tatttatata actaaaggtt aaaagttaat
   159001 tttatgactt ctatccttta gttttttgta tttaaattat tattttttgc aaatcattct
   159061 tactagaaat tacttattat aactaattcc caataattat ataattttgt gctcatactg
   159121 aaatttttaa ataaactatt aatttatatt atatatgatt tttcaaaata aaaaacatat
   159181 taactattaa atcaatatgt tttcgtggat tccaatggtg gagaccgagg agaatttata
   159241 agtggttatt tgattgtttt gttggttttt ataagtatag gtatatggct atttggtcat
   159301 gatgttgaag caatttttct ggttattttt tattgtctat ttttgtagtt ggggtattat
   159361 tggggtataa ttttctactt tccaaaatta ttgatacttc aataatataa attaaattct
   159421 tagttaagtt ttttaatgaa taggtaaata ttatttgtac tcataacaat atagtttacg
   159481 cataatttta tatatatttt ctggtatatc tgcaactaac ttagtgtaat ttaaacgata
   159541 ttagagatac ttaaaaaaca aatatatgaa agatttataa ctaacttagt gtaatttaat
   159601 tgattgctct gcttctgtat ttttaattaa gttgtttgaa ttatttataa tataacctcc
   159661 ttaccacttt aattgtgagt catctggatt atatattcct gtctctttat ttatgacaat
   159721 ttccttgcta ttataatttc cctctagtat cttagtaaaa ttacttgaat tcattatcca
   159781 atcaaaattt gctttccatc ctgtattatt atttccattc agaaaacttg ttttactaac
   159841 tatatttata acctctaata cagtttcttt atcatattct tttattcttg aatttattct
   159901 cctctttctt gtatctgtta gtttcttgac ctttgaaagt tcaatacaag ttgagttaaa
   159961 tttgcttatg atttcactat atataatatt attttcattc tttatattct tgattgttgt
   160021 tgactgattg ttaatagtct gttgattagg ttgttgattt tctatattct cttgataaag
   160081 ctcccagttt tcaatagtta ttactatata cttgtttgtt gtttcgtatg ttagaaaacc
   160141 agcattttta aaaaccaaca aacaacttct aaccatttga taactaactc ctttaccaca
   160201 tctttcagct attttgctat atgaagaaat aaattgtcca aactttattt ttatcttttt
   160261 attatctata aaaacatgat tttctttatg actagccata agtaatagag ttattaatat
   160321 tacctttctt tctggtttaa tatctttcca aattgattta tccaacaact ccctataaag
   160381 ctttatccac cctttattgc tcaattgcaa acacctactt taagactata acttgatacc
   160441 atttgcattt tcaataaacc aatcatctaa tttatttttt attatgtata ctcgattatt
   160501 tatccatata caagggaatc ctttgttttt agaatgacat aactgcctaa attttgattc
   160561 tcctatagga taaagcttag atgcttcttt acatgttata agctcagctt tatttctttt
   160621 cgcattttca ataattttat atccttgctt tttttcttgt gcttcttctt cattctttac
   160681 aataatgttt aaagtggctt gtaatgtctt taaaacctct aaattattat tctctttcat
   160741 attttaatcc tccttactaa aaaataattc ttctactgtt gtatctaaag ctctagatag
   160801 tttaatcatc aaatcattgc ttggattatt agccttacct gtttccaagt ttgataaata
   160861 atatcttgat ataccaactc tatctgccag ttcttgttgc tttagacctt ttttaatcct
   160921 aaatattttt aaattgattc ccatactttt tcctcctttt ttctagttta cattcgtaaa
   160981 ctttacattt taattataat gtcgatatat gtgtactgtt aataagaata tattattttt
   161041 ctgttctcat ttgtgtactt ttgggatata ctttatacga ggtgataata ttgcaaattg
   161101 gaaaaaactt aaaaaagata agaaaacaaa aagagctaac gcagattcaa cttgctgaaa
   161161 ttagtggcat ctcaagaaat gctctaataa attatgaaaa tgataaaaga atacctagta
   161221 tagatacctt atcaaaactc gctaaagctt tgaaaattga aaagactatc ttttattttg
   161281 atattgaaaa tgaagtaatg actaatgaag atgttttata ccttttacag tctttattcc
   161341 cagaagaata ctattctttt gatgaatttt taaatgctat ttcaaatctt atggaagatg
   161401 atattagaat tacctcaagt ttattgctag gtgcctggtc tgataaagac caatattata
   161461 aacttggtga aaaattagaa ctaaatgaaa atcaagttta taattggata ctttcagatt
   161521 gtatatctaa tactgaatta gatttttcat tacatcctga tgacataaaa gaaattatta
   161581 aaaatgatgt tcttacaaaa caatcaattg atgaattatt agatattggt ctatcagaag
   161641 aaagtataga aacaatctat gattacttta gtgactcaac agataatgga agtaatattc
   161701 gactaaaaaa attaatatct caaaaagaaa atattactat taaaaataat gattacttta
   161761 aattattaca agaaaataac gaactaaagg aaaaaaatga aaagcttgaa aatacactta
   161821 aagaaataaa aaaactacta actaaaatat aaaataatat caatactatc taaagcaatg
   161881 ataaaaaact atgaatggag ttacaattat gaataaatca tatatgctaa aatacacata
   161941 taaatcccct actaatttat ttcatggaga taaaaaatat actctaacat acactaagag
   162001 agttatgagt aatttagtat atgatatggg ataatctaga aaataactcc tttacatgtt
   162061 tagaagtaca atcattgttt gatgatatat ttaaggtgaa attatgatga ataatacaat
   162121 tggagaaaag attaaacaat atagaaaatc gataaatatg tcaagggatg agctagccaa
   162181 caagattggt tgttcagttc atgctatagc taaatatgag caaaatcaaa gaatgcctag
   162241 tttagatatg ataagaaaaa tagctactgc tttatcaatt gctataaata aactcattgt
   162301 tgaagaaaat gatttagata ctttaacaaa taataatatt aatttaaaag tatttgataa
   162361 agagttggat ttagtaattc acatattaga aaattatggt tatgatataa aaacagacta
   162421 taaaaaaaag tttgaaatta cagataatgc agatacaata aaaccaatta acctaaactt
   162481 ctctgacttc aaagacttct ccaaaaatct aaattgggtg ataaatggtc ttgttgaaaa
   162541 ttttatacaa gaaaactcta atggtcttat tgaagatgag gatgaagaat attagtattg
   162601 cacattttca aaatatgagt ttacctatta acttttatac attcatagtt aataaataaa
   162661 aattagatat gaaaggagct aaaatcatga ataaatcata tataccaaaa tacacacata
   162721 aattccctac taatatacct catggagata aaaaatatac tttaacatac attagaagaa
   162781 tgataagtga atttgtatat gatatgggta acctagaaaa taaccccttc acattcccag
   162841 aagtacaaac attacttgat ggtataaccg taggcggaca taaattaagt gaccaaaatc
   162901 aaatactaaa tataaaatca tcatgggatt atgtaataaa attaagtaac aaagaaaact
   162961 tatctttaaa taaagataca atttgctcta tacataaaat agttgcaaaa gatgaagctc
   163021 taatcgttgg agatttcaga aatggtaata taggtatagc tggtactact caatatgaat
   163081 gcatagaagc cactctatta aatgatttat ttgtaaatga cataaatatc ataaataaaa
   163141 taactaaccc attagaaaag gctataataa taaatttatg gttgtcctat tgccaattct
   163201 tctatgatgg caacaaaaga actgctagac ttacctcaaa cctaatactt ataaataatg
   163261 atataggagt tctatcaata ccagctaaac ataaacaaga gtacaacaca ttaatgctaa
   163321 acttctatga aacactagaa gctgatgaag ttataaaatt cttattagag aaatgtatta
   163381 cattctttga tggatataac tataaatcat ataaggagct gtttaaaaat ggcaactaaa
   163441 agagctaatg gagaaggctc tatcggaaaa tataaagatg gttggcgttc ccgtataatg
   163501 attggctata atgaagatgg taaaccactg agaaaagaat tttatggtaa gactcaaaag
   163561 gaagttaaag ataaattaga tgcttataaa aaacaatatt atttaagctc tgatatttca
   163621 gatgataaaa taactttaga gcattggttt tacaattggt tatttgaata tagaataaaa
   163681 gatttaaaac ccaagtcatt tgaaagatat gaaagcatct atcgtaatta tattaaagat
   163741 actgatttag gcaatgttaa attaaagtac ttaagagtat ctcacataca aaaatattac
   163801 aatagattgc ttgattccaa taaaagtata cctactataa ggcaaataaa cactaaactg
   163861 aaaacctgct tatcagaagc tgaaaaacaa ggtcttatac aacgtaacta ttgtactatg
   163921 gtaaatatac cagttgagaa aaaagaaaac aaacttgaaa tattgactct tgaacaacaa
   163981 aagagtttta taaaagctat agatgggcat aaattagagg tattattttt acttgctctt
   164041 ggtactggac ttagattagg agaattatta ggacttaaat ggtttgatat tgattttaaa
   164101 aagtctaatt taacagttaa aagaactctt caaagaacat attttataga taaaactgga
   164161 aatagagagc ttaaagtatt agagcaaggg ccaaagacat caaattctta cagaactgta
   164221 cctattccaa aagatgtttt aaataaattg aaagagcata aagtaaatca aaatacagat
   164281 atattaaagg ctggagaatt atatataaat aataattatg tattttgcaa tgaattaggc
   164341 atccctatag atgataaaag acctttaagg aatttaaagt ctatattaaa tagcttaaat
   164401 atagagccta taaagtttca tggtcttagg aaaacttatg ctactagact ttttgagaat
   164461 gatgttcctc ctaaaactgt acaagtttta atgggtcatt atgatatatc aataactttg
   164521 aatatatata ctcaagttat ggaagataag aaagttgaag ctgtagaaaa gttggataaa
   164581 atattttcat tgtaaaaatc aaatacatat aaatattgtg atttcatata gttaattaca
   164641 aaatcaaaat aaggatacaa attaatttta tattatattg tatccttatt tcgtatctag
   164701 ttttaattat ttatcttgga tagcccttat ggtacattaa tccattttct aacattaatt
   164761 cttgagccaa gtatatatga cccttacagt gcatatctga tacaccctca cttataagtt
   164821 tatatgtttc agaagtatat aaataatcca tactttcttc caagctctta cctgtttgtt
   164881 tggaaaattc taatatgatt tttttatata gtatttgtaa taatgtttta tttgcttcca
   164941 taatcattat acctcctctt catacctaaa ctttaaatat ttatctatta cattttgatt
   165001 ggttatacat atttgttcat ttggtttata gtattttaat ctttttaaag cttcatcttt
   165061 ttcaataaga ttatcttgat acagttctat tgtattgtaa atcttatcat cagcaatacc
   165121 acctattata atgtcatatt tcatatatat atcactcata tttctacatt ctattataaa
   165181 atcaagccat tctaaattat aactatcgaa gatttttacc ttgcagtttt cttttaattt
   165241 atcaatatct aaagaataac tatttaaata tgctttttta cctctttttt taaaacgctc
   165301 tgtccagtta attgcttgtg tctttatact ggttacatag aatccttttc caaaatctaa
   165361 agaatctctt gaaaaggtaa tactaggcgt ctttaccaca caatatgaac catgatatac
   165421 aatcattata tcacaccctt ttctttaagt acttgcatta aatcttccac tatgtaacct
   165481 ttactttgag aatgtagtgc ttcatagcaa ggtattatat agttatctaa aatatcagta
   165541 tcatgtttaa gaagtttata aactccttct gaatctatat tcaatttttc tgctaaagct
   165601 tcaatgcaaa aaatagaaaa ttctagtttt ctttcatcca ttacaaacct caactcctat
   165661 caagcttata taatatatat ttttactaat taacaactta aactgtctta catttataaa
   165721 aatattatat cataaagtag atattaaaat tctatgttac ctattatcat aataaacaaa
   165781 taaaataata aacaaataaa ataataaaca aataaaaact ttttatacag cctaaatgca
   165841 ccccaatata cccccaaaaa aacctcattt tctgtggttg gggtacggtt ggtggatttc
   165901 ttctccaaaa taaaaaatac tagtcaacaa agactagtat ttccaagtat ttcatcattc
   165961 ttttttcaaa attggtggag acgaggggag tcgaacccct gtccgcaaat cttttccttg
   166021 ctgcatctac atgcttagcc aacttcacta atatctcacc tcacatagcg ccaagtggca
   166081 ggctctatgc ttagccagtc ccaattaatc tacttcaagt cgagacaccc ctaaagtagt
   166141 tccctgcata atgacgtcca gtcttagtcg gcaggaggac taagagggac gagcagcaac
   166201 taggctgcta tcgcgaaatt atcgtctgcg tttattttaa agttccccag tttttacgtg
   166261 acccagagta acacgacatg cagcctcaag ttccaaaccc acgtcgaaac ctttacgccc
   166321 ccttgagtag tttatagtcc agtagacttt tctcaaactt tatcaccatt tttattaaat
   166381 ttttaatgta tatataatat aatactttta agaataaaaa tcaatgttat gttctagata
   166441 ataaagaatt ttattctaaa aaatacagtt ttatctagtt taatacttac ctgtcatttc
   166501 tctttctata cgtctttgtg catctttctt agccatatct tgacgtttat catatagttt
   166561 tttacctttt gctaaggcaa tctctacttt aactttaccg ttttttagat acaaactaag
   166621 tggtataagt gaatacccct ttatagtagt tgctccaata agctttctta tttcatgctt
   166681 atgaagtaat agttttctaa ctcttaaaga atcaacattg aatatatttc cttgctcata
   166741 tggacttata tgaacttgtt ttaaaaatac ttcgctatta tctacagatg caaatccatc
   166801 acttaggtta actttgcctt gtcttattga ttttacttct gttcctttta attcaattcc
   166861 acattcataa gtttcttcta taaaatattc atgtcttgct cttttgtttg ttgctaatat
   166921 ttttttacca gccatataaa tctcaccttc tttgctagaa atttgttcca taaatgttag
   166981 aaatttacta aatatttaat gttgccaaat tatttgacta acttgtatga taacatattt
   167041 aggcatttta gtcaatattt cactgatata ttaagttagt taggctatat ataattaagt
   167101 aatataaatg tatgaaaata gctaaaaaac tacttcgaat atacttaata ctaaactaac
   167161 tctaaccagt aatactaatt tataaatttc aaaacaaaaa tattacatat tata
//
LOCUS       DAGQVA010000002       124816 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.002, whole genome shotgun sequence.
ACCESSION   DAGQVA010000002 DAGQVA010000000
VERSION     DAGQVA010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 124816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 124816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..124816
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.002"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(632..883)
                     /locus_tag="MIV85_000131"
     CDS             complement(632..883)
                     /locus_tag="MIV85_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959511.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(1129..1284)
                     /locus_tag="MIV85_000132"
     CDS             complement(1129..1284)
                     /locus_tag="MIV85_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HBY2959512.1"
                     /translation="MALEVKIEVKIIKDVVILNITHWKKETSLLTVKIARGQGDLSYV
                     KYFTNES"
     gene            1963..2187
                     /locus_tag="MIV85_000133"
     CDS             1963..2187
                     /locus_tag="MIV85_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959513.1"
                     /translation="MDVNQRIKYIRENMNSSQKELLEKTNINTSVMNRIESGERPTRE
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     repeat_region   2474..3622
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2539..2567
                     /rpt_unit_seq="ctttacataccacttagttaatataaaac"
     gene            complement(4276..4428)
                     /locus_tag="MIV85_000134"
     CDS             complement(4276..4428)
                     /locus_tag="MIV85_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959514.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
     gene            complement(4500..5527)
                     /locus_tag="MIV85_000135"
                     /pseudo
     CDS             complement(4500..5527)
                     /locus_tag="MIV85_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
     gene            5718..6539
                     /locus_tag="MIV85_000136"
     CDS             5718..6539
                     /locus_tag="MIV85_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBY2959515.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIKIKD
                     YEVAYNLLSKDSKENVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            6664..8181
                     /locus_tag="MIV85_000137"
     CDS             6664..8181
                     /locus_tag="MIV85_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBY2959516.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            8204..8488
                     /locus_tag="MIV85_000138"
     CDS             8204..8488
                     /locus_tag="MIV85_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2959517.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(8585..10249)
                     /locus_tag="MIV85_000139"
     CDS             complement(8585..10249)
                     /locus_tag="MIV85_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBY2959518.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(10321..11568)
                     /locus_tag="MIV85_000140"
     CDS             complement(10321..11568)
                     /locus_tag="MIV85_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBY2959519.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            complement(11555..12229)
                     /locus_tag="MIV85_000141"
     CDS             complement(11555..12229)
                     /locus_tag="MIV85_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBY2959520.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            complement(12401..13480)
                     /gene="mltG"
                     /locus_tag="MIV85_000142"
     CDS             complement(12401..13480)
                     /gene="mltG"
                     /locus_tag="MIV85_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBY2959521.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYMDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            complement(13693..15018)
                     /locus_tag="MIV85_000143"
     CDS             complement(13693..15018)
                     /locus_tag="MIV85_000143"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBY2959522.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            complement(15222..16034)
                     /locus_tag="MIV85_000144"
     CDS             complement(15222..16034)
                     /locus_tag="MIV85_000144"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBY2959523.1"
                     /translation="MFEKIAQSSKFINSKSDIKPKIGLILGSGLGDLANDIEDPVAIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            complement(16081..17253)
                     /locus_tag="MIV85_000145"
     CDS             complement(16081..17253)
                     /locus_tag="MIV85_000145"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBY2959524.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            complement(17295..18209)
                     /locus_tag="MIV85_000146"
     CDS             complement(17295..18209)
                     /locus_tag="MIV85_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBY2959525.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            complement(18221..18826)
                     /locus_tag="MIV85_000147"
     CDS             complement(18221..18826)
                     /locus_tag="MIV85_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBY2959526.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            complement(18894..19430)
                     /locus_tag="MIV85_000148"
     CDS             complement(18894..19430)
                     /locus_tag="MIV85_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBY2959527.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            complement(19432..20499)
                     /locus_tag="MIV85_000149"
     CDS             complement(19432..20499)
                     /locus_tag="MIV85_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBY2959528.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            complement(20504..21328)
                     /locus_tag="MIV85_000150"
     CDS             complement(20504..21328)
                     /locus_tag="MIV85_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBY2959529.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            complement(21336..22028)
                     /locus_tag="MIV85_000151"
     CDS             complement(21336..22028)
                     /locus_tag="MIV85_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBY2959530.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            complement(22052..22927)
                     /locus_tag="MIV85_000152"
     CDS             complement(22052..22927)
                     /locus_tag="MIV85_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBY2959531.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            complement(22945..24066)
                     /locus_tag="MIV85_000153"
     CDS             complement(22945..24066)
                     /locus_tag="MIV85_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959532.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            complement(24479..25303)
                     /gene="spo0A"
                     /locus_tag="MIV85_000154"
     CDS             complement(24479..25303)
                     /gene="spo0A"
                     /locus_tag="MIV85_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBY2959533.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            complement(25445..26503)
                     /locus_tag="MIV85_000155"
     CDS             complement(25445..26503)
                     /locus_tag="MIV85_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBY2959534.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGGAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            26664..27104
                     /locus_tag="MIV85_000156"
     CDS             26664..27104
                     /locus_tag="MIV85_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2959535.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            27165..27656
                     /locus_tag="MIV85_000157"
     CDS             27165..27656
                     /locus_tag="MIV85_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2959536.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(27749..28615)
                     /locus_tag="MIV85_000158"
     CDS             complement(27749..28615)
                     /locus_tag="MIV85_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959537.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDIDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(28830..30509)
                     /gene="recN"
                     /locus_tag="MIV85_000159"
     CDS             complement(28830..30509)
                     /gene="recN"
                     /locus_tag="MIV85_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBY2959538.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            complement(30529..31341)
                     /locus_tag="MIV85_000160"
     CDS             complement(30529..31341)
                     /locus_tag="MIV85_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBY2959539.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            complement(31474..33339)
                     /locus_tag="MIV85_000161"
     CDS             complement(31474..33339)
                     /locus_tag="MIV85_000161"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBY2959540.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            complement(33373..33810)
                     /locus_tag="MIV85_000162"
     CDS             complement(33373..33810)
                     /locus_tag="MIV85_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBY2959541.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            complement(33840..34727)
                     /locus_tag="MIV85_000163"
     CDS             complement(33840..34727)
                     /locus_tag="MIV85_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBY2959542.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            complement(34730..34945)
                     /gene="xseB"
                     /locus_tag="MIV85_000164"
     CDS             complement(34730..34945)
                     /gene="xseB"
                     /locus_tag="MIV85_000164"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBY2959543.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            complement(34947..36152)
                     /locus_tag="MIV85_000165"
     CDS             complement(34947..36152)
                     /locus_tag="MIV85_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBY2959544.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            complement(36149..37219)
                     /locus_tag="MIV85_000166"
     CDS             complement(36149..37219)
                     /locus_tag="MIV85_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBY2959545.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            complement(37203..37709)
                     /gene="nusB"
                     /locus_tag="MIV85_000167"
     CDS             complement(37203..37709)
                     /gene="nusB"
                     /locus_tag="MIV85_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBY2959546.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            complement(37794..38156)
                     /locus_tag="MIV85_000168"
     CDS             complement(37794..38156)
                     /locus_tag="MIV85_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBY2959547.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            complement(38266..38955)
                     /locus_tag="MIV85_000169"
     CDS             complement(38266..38955)
                     /locus_tag="MIV85_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBY2959548.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSYSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            complement(38982..39536)
                     /locus_tag="MIV85_000170"
     CDS             complement(38982..39536)
                     /locus_tag="MIV85_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBY2959549.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            complement(39548..40165)
                     /locus_tag="MIV85_000171"
     CDS             complement(39548..40165)
                     /locus_tag="MIV85_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBY2959550.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            complement(40225..41430)
                     /gene="spoIIIAE"
                     /locus_tag="MIV85_000172"
     CDS             complement(40225..41430)
                     /gene="spoIIIAE"
                     /locus_tag="MIV85_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBY2959551.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            complement(41515..41901)
                     /gene="spoIIIAD"
                     /locus_tag="MIV85_000173"
     CDS             complement(41515..41901)
                     /gene="spoIIIAD"
                     /locus_tag="MIV85_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBY2959552.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            complement(41917..42114)
                     /gene="spoIIIAC"
                     /locus_tag="MIV85_000174"
     CDS             complement(41917..42114)
                     /gene="spoIIIAC"
                     /locus_tag="MIV85_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBY2959553.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            complement(42131..42652)
                     /locus_tag="MIV85_000175"
     CDS             complement(42131..42652)
                     /locus_tag="MIV85_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBY2959554.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            complement(42642..43610)
                     /gene="spoIIIAA"
                     /locus_tag="MIV85_000176"
     CDS             complement(42642..43610)
                     /gene="spoIIIAA"
                     /locus_tag="MIV85_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBY2959555.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            complement(43834..45819)
                     /locus_tag="MIV85_000177"
     CDS             complement(43834..45819)
                     /locus_tag="MIV85_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBY2959556.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            complement(45908..46447)
                     /locus_tag="MIV85_000178"
     CDS             complement(45908..46447)
                     /locus_tag="MIV85_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2959557.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            complement(46653..47966)
                     /locus_tag="MIV85_000179"
     CDS             complement(46653..47966)
                     /locus_tag="MIV85_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBY2959558.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVVMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYDENLKKIV"
     gene            complement(47988..48713)
                     /locus_tag="MIV85_000180"
     CDS             complement(47988..48713)
                     /locus_tag="MIV85_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBY2959559.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            complement(48748..48993)
                     /locus_tag="MIV85_000181"
     CDS             complement(48748..48993)
                     /locus_tag="MIV85_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBY2959560.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            complement(49344..51344)
                     /locus_tag="MIV85_000182"
     CDS             complement(49344..51344)
                     /locus_tag="MIV85_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2959561.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSELSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            complement(51375..53093)
                     /locus_tag="MIV85_000183"
     CDS             complement(51375..53093)
                     /locus_tag="MIV85_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2959562.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKHDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            complement(53319..54557)
                     /gene="fabF"
                     /locus_tag="MIV85_000184"
     CDS             complement(53319..54557)
                     /gene="fabF"
                     /locus_tag="MIV85_000184"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBY2959563.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            complement(54586..54810)
                     /gene="acpP"
                     /locus_tag="MIV85_000185"
     CDS             complement(54586..54810)
                     /gene="acpP"
                     /locus_tag="MIV85_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBY2959564.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            complement(54864..55613)
                     /gene="fabG"
                     /locus_tag="MIV85_000186"
     CDS             complement(54864..55613)
                     /gene="fabG"
                     /locus_tag="MIV85_000186"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBY2959565.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            complement(55613..56563)
                     /gene="fabD"
                     /locus_tag="MIV85_000187"
     CDS             complement(55613..56563)
                     /gene="fabD"
                     /locus_tag="MIV85_000187"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBY2959566.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            complement(56579..57508)
                     /gene="fabK"
                     /locus_tag="MIV85_000188"
     CDS             complement(56579..57508)
                     /gene="fabK"
                     /locus_tag="MIV85_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBY2959567.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            complement(57617..58603)
                     /locus_tag="MIV85_000189"
     CDS             complement(57617..58603)
                     /locus_tag="MIV85_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBY2959568.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            complement(58629..59651)
                     /gene="plsX"
                     /locus_tag="MIV85_000190"
     CDS             complement(58629..59651)
                     /gene="plsX"
                     /locus_tag="MIV85_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBY2959569.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            complement(59662..60219)
                     /gene="fapR"
                     /locus_tag="MIV85_000191"
     CDS             complement(59662..60219)
                     /gene="fapR"
                     /locus_tag="MIV85_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBY2959570.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            complement(60426..60602)
                     /gene="rpmF"
                     /locus_tag="MIV85_000192"
     CDS             complement(60426..60602)
                     /gene="rpmF"
                     /locus_tag="MIV85_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBY2959571.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            complement(60627..61151)
                     /locus_tag="MIV85_000193"
     CDS             complement(60627..61151)
                     /locus_tag="MIV85_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBY2959572.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            complement(61244..62440)
                     /locus_tag="MIV85_000194"
     CDS             complement(61244..62440)
                     /locus_tag="MIV85_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBY2959573.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            62903..64183
                     /locus_tag="MIV85_000195"
     CDS             62903..64183
                     /locus_tag="MIV85_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBY2959574.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(64446..65837)
                     /locus_tag="MIV85_000196"
     CDS             complement(64446..65837)
                     /locus_tag="MIV85_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBY2959575.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(65848..67068)
                     /locus_tag="MIV85_000197"
     CDS             complement(65848..67068)
                     /locus_tag="MIV85_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBY2959576.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(67082..67870)
                     /locus_tag="MIV85_000198"
     CDS             complement(67082..67870)
                     /locus_tag="MIV85_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003402402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBY2959577.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKNENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(67887..69161)
                     /gene="larA"
                     /locus_tag="MIV85_000199"
     CDS             complement(67887..69161)
                     /gene="larA"
                     /locus_tag="MIV85_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBY2959578.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(69279..69992)
                     /locus_tag="MIV85_000200"
     CDS             complement(69279..69992)
                     /locus_tag="MIV85_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBY2959579.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            70117..71376
                     /locus_tag="MIV85_000201"
     CDS             70117..71376
                     /locus_tag="MIV85_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBY2959580.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            71656..72222
                     /locus_tag="MIV85_000202"
     CDS             71656..72222
                     /locus_tag="MIV85_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBY2959581.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(72423..73628)
                     /locus_tag="MIV85_000203"
     CDS             complement(72423..73628)
                     /locus_tag="MIV85_000203"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBY2959582.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(73731..73837)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(73929..74297)
                     /locus_tag="MIV85_000204"
     CDS             complement(73929..74297)
                     /locus_tag="MIV85_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBY2959583.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(74349..75626)
                     /gene="obgE"
                     /locus_tag="MIV85_000205"
     CDS             complement(74349..75626)
                     /gene="obgE"
                     /locus_tag="MIV85_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBY2959584.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(75737..76027)
                     /gene="rpmA"
                     /locus_tag="MIV85_000206"
     CDS             complement(75737..76027)
                     /gene="rpmA"
                     /locus_tag="MIV85_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBY2959585.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(76041..76358)
                     /locus_tag="MIV85_000207"
     CDS             complement(76041..76358)
                     /locus_tag="MIV85_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBY2959586.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(76373..76684)
                     /gene="rplU"
                     /locus_tag="MIV85_000208"
     CDS             complement(76373..76684)
                     /gene="rplU"
                     /locus_tag="MIV85_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBY2959587.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(76785..78206)
                     /locus_tag="MIV85_000209"
     CDS             complement(76785..78206)
                     /locus_tag="MIV85_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBY2959588.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(78224..78925)
                     /locus_tag="MIV85_000210"
     CDS             complement(78224..78925)
                     /locus_tag="MIV85_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBY2959589.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(78927..80771)
                     /locus_tag="MIV85_000211"
     CDS             complement(78927..80771)
                     /locus_tag="MIV85_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBY2959590.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            81090..82283
                     /locus_tag="MIV85_000212"
     CDS             81090..82283
                     /locus_tag="MIV85_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBY2959591.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(82495..83577)
                     /locus_tag="MIV85_000213"
     CDS             complement(82495..83577)
                     /locus_tag="MIV85_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBY2959592.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(84141..84932)
                     /locus_tag="MIV85_000214"
     CDS             complement(84141..84932)
                     /locus_tag="MIV85_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959593.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(84936..85265)
                     /locus_tag="MIV85_000215"
     CDS             complement(84936..85265)
                     /locus_tag="MIV85_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959594.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(85750..86163)
                     /locus_tag="MIV85_000216"
     CDS             complement(85750..86163)
                     /locus_tag="MIV85_000216"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBY2959595.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(86204..87334)
                     /gene="rodA"
                     /locus_tag="MIV85_000217"
     CDS             complement(86204..87334)
                     /gene="rodA"
                     /locus_tag="MIV85_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBY2959596.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(87419..87703)
                     /gene="minE"
                     /locus_tag="MIV85_000218"
     CDS             complement(87419..87703)
                     /gene="minE"
                     /locus_tag="MIV85_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBY2959597.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(87721..88518)
                     /gene="minD"
                     /locus_tag="MIV85_000219"
     CDS             complement(87721..88518)
                     /gene="minD"
                     /locus_tag="MIV85_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBY2959598.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(88542..89225)
                     /locus_tag="MIV85_000220"
     CDS             complement(88542..89225)
                     /locus_tag="MIV85_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBY2959599.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(89323..92301)
                     /locus_tag="MIV85_000221"
     CDS             complement(89323..92301)
                     /locus_tag="MIV85_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBY2959600.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(92313..92801)
                     /gene="mreD"
                     /locus_tag="MIV85_000222"
     CDS             complement(92313..92801)
                     /gene="mreD"
                     /locus_tag="MIV85_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBY2959601.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(92816..93709)
                     /gene="mreC"
                     /locus_tag="MIV85_000223"
     CDS             complement(92816..93709)
                     /gene="mreC"
                     /locus_tag="MIV85_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBY2959602.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(93719..94729)
                     /locus_tag="MIV85_000224"
     CDS             complement(93719..94729)
                     /locus_tag="MIV85_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBY2959603.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(94850..95509)
                     /gene="radC"
                     /locus_tag="MIV85_000225"
     CDS             complement(94850..95509)
                     /gene="radC"
                     /locus_tag="MIV85_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBY2959604.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(95554..96138)
                     /gene="maf"
                     /locus_tag="MIV85_000226"
     CDS             complement(95554..96138)
                     /gene="maf"
                     /locus_tag="MIV85_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBY2959605.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(96358..97329)
                     /locus_tag="MIV85_000227"
     CDS             complement(96358..97329)
                     /locus_tag="MIV85_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBY2959606.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(97345..97920)
                     /gene="rsxA"
                     /locus_tag="MIV85_000228"
     CDS             complement(97345..97920)
                     /gene="rsxA"
                     /locus_tag="MIV85_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBY2959607.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(97935..98528)
                     /locus_tag="MIV85_000229"
     CDS             complement(97935..98528)
                     /locus_tag="MIV85_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBY2959608.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(98541..99110)
                     /locus_tag="MIV85_000230"
     CDS             complement(98541..99110)
                     /locus_tag="MIV85_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBY2959609.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(99110..100087)
                     /locus_tag="MIV85_000231"
     CDS             complement(99110..100087)
                     /locus_tag="MIV85_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBY2959610.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADISSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(100110..101447)
                     /gene="rsxC"
                     /locus_tag="MIV85_000232"
     CDS             complement(100110..101447)
                     /gene="rsxC"
                     /locus_tag="MIV85_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBY2959611.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(101663..102607)
                     /locus_tag="MIV85_000233"
     CDS             complement(101663..102607)
                     /locus_tag="MIV85_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959612.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(102718..103992)
                     /locus_tag="MIV85_000234"
     CDS             complement(102718..103992)
                     /locus_tag="MIV85_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBY2959613.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(104124..104495)
                     /locus_tag="MIV85_000235"
     CDS             complement(104124..104495)
                     /locus_tag="MIV85_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBY2959614.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(104723..105322)
                     /locus_tag="MIV85_000236"
     CDS             complement(104723..105322)
                     /locus_tag="MIV85_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959615.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(105523..105735)
                     /locus_tag="MIV85_000237"
     CDS             complement(105523..105735)
                     /locus_tag="MIV85_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBY2959616.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(105808..107523)
                     /locus_tag="MIV85_000238"
     CDS             complement(105808..107523)
                     /locus_tag="MIV85_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2959617.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNITSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(107523..108077)
                     /locus_tag="MIV85_000239"
     CDS             complement(107523..108077)
                     /locus_tag="MIV85_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBY2959618.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(108070..108672)
                     /locus_tag="MIV85_000240"
     CDS             complement(108070..108672)
                     /locus_tag="MIV85_000240"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBY2959619.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(108681..111329)
                     /gene="polA"
                     /locus_tag="MIV85_000241"
     CDS             complement(108681..111329)
                     /gene="polA"
                     /locus_tag="MIV85_000241"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBY2959620.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            111481..111568
                     /locus_tag="MIV85_000242"
     tRNA            111481..111568
                     /locus_tag="MIV85_000242"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111515..111517,aa:Leu,seq:caa)
     gene            complement(111755..112198)
                     /locus_tag="MIV85_000243"
     CDS             complement(111755..112198)
                     /locus_tag="MIV85_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959621.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(112201..112398)
                     /locus_tag="MIV85_000244"
     CDS             complement(112201..112398)
                     /locus_tag="MIV85_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959622.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(112590..113456)
                     /locus_tag="MIV85_000245"
     CDS             complement(112590..113456)
                     /locus_tag="MIV85_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2959623.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(113682..114551)
                     /locus_tag="MIV85_000246"
     CDS             complement(113682..114551)
                     /locus_tag="MIV85_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2959624.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(115057..115278)
                     /locus_tag="MIV85_000247"
     CDS             complement(115057..115278)
                     /locus_tag="MIV85_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959625.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(115780..116760)
                     /locus_tag="MIV85_000248"
     CDS             complement(115780..116760)
                     /locus_tag="MIV85_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959626.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(116924..117796)
                     /locus_tag="MIV85_000249"
     CDS             complement(116924..117796)
                     /locus_tag="MIV85_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBY2959627.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITFKYEK"
     gene            complement(117960..118511)
                     /locus_tag="MIV85_000250"
     CDS             complement(117960..118511)
                     /locus_tag="MIV85_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2959628.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(118531..119433)
                     /locus_tag="MIV85_000251"
     CDS             complement(118531..119433)
                     /locus_tag="MIV85_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBY2959629.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDD
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(119448..121820)
                     /locus_tag="MIV85_000252"
     CDS             complement(119448..121820)
                     /locus_tag="MIV85_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBY2959630.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(122041..122730)
                     /locus_tag="MIV85_000253"
     CDS             complement(122041..122730)
                     /locus_tag="MIV85_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959631.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVYDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(122971..124350)
                     /locus_tag="MIV85_000254"
     CDS             complement(122971..124350)
                     /locus_tag="MIV85_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2959632.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENVNKYIRIKGTMTRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(124344..>124816)
                     /gene="rgbR"
                     /locus_tag="MIV85_000255"
     CDS             complement(124344..>124816)
                     /gene="rgbR"
                     /locus_tag="MIV85_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBY2959633.1"
                     /translation="IFVTSLIDYVQEGYEVRAYRYLLKPIELEELKKHVLTCIKDIEI
                     NKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIHTINKNFDIKYSLGKIEKELNPYK
                     FIRCHKSFIVNLRYVENIKPNTAILESGEEVPISRYRYKEVKEKFLKFLGDTIC"
BASE COUNT        39338 a        22723 c        13116 g        49639 t
ORIGIN      
        1 taacctactg gatatcttaa tttaatatat gtacactatt catatcttaa tagtcaatat
       61 tattcatttt taatagctct ttttagatgt cagaattatt atattttgaa atttattaaa
      121 tttttgcatt aaaaaaacta gaaattaatt taagtcttga attacttata actttctacg
      181 tatctacctt tatattctta ctctgatttt atatctaata tcaactcttc atcaaagcta
      241 ttaaatatac ctctaattga gtcaattatt tcacttactt cacctttaat ttttatatta
      301 acttcaacca tttcaaatct catcttttta tcttataatt tctataagtt tttttattta
      361 ttgtgttgct tactttgacc agcacttttt tatttaatag tctaaatgat attttttacc
      421 agttttaata tccttaaata ctatatttac taaaaactta taatttcttt taatacatag
      481 ttaatacatt cttattacta ataacaatac tcaacaattt tatcgccttt tttcaaatat
      541 gatttaactt ttttattcct aattatttaa aaatagttgt ccaattttct tctatgagaa
      601 agtgctaagt attagcaact tctctattct cttaactttc tactgtctca actttcttca
      661 tagctatatt aatagctact tctttagcta cttcattgaa ctcttcccat cttctcctat
      721 tttcttcatc agatatacgt ggatatacta tataaacttc tgtgttttga ttagctataa
      781 ttttttcatc atattctata tttttttctt tatcatattt gtatggttta aattgttgta
      841 gtattttcat aacatcaccc cttgttataa aatatgaact cataaacttg tcttatactt
      901 atttaattgt tacaattttt acttaaaatc actttatatt ctatatatta aagctaaatc
      961 ctttacaaaa gtaacatatt cttctataag tttcttatcc tcttatatag tatctagttt
     1021 gtttaactta tctcttttaa acttacatac gccttcttct gccattcgtc ttttattaat
     1081 tgttaacatt atttcaatag acacaccaaa actcttgtta agaagctctt agctctcatt
     1141 agtaaaatat tttacataac ttaaatcacc ttgacctcta gcaattttaa ctgttaatag
     1201 acttgtttct tttttccaat gtgttatatt taatataaca acatctttta ttattttaac
     1261 ttctattttt acctctaatg ccatattatt gcttgattaa tttgtatcct taaatattaa
     1321 attttctatt aatacatctt ctatacagct tagtttctct cgcttaatct tgaaatatat
     1381 tttctctaaa ttgtcaaatt gttctcaagt tttatcaata tctaatattt tgcagtgtct
     1441 atttgcacat ctttcggtcc aaatgtataa ttgactagaa tgttttgaaa tcaactgact
     1501 attagtaggt tagttcttaa attctttcaa atactcgaat tgtaataaaa cataatttac
     1561 attctcttta tttctattga agctagttta tatattgttt acatcatttt catatatatc
     1621 tgctagttgc tatgtattta aaattctctt attatttctt tatattactt gtaaattatt
     1681 catccttatc atcctcttaa ttaaattttc tatatcataa tcaagtatct tagatagttt
     1741 ataggtaata tatcaactct aattgaatat taccctttcc tgtacttaaa ataagttgat
     1801 gcatttttaa aacctaactc ttttgcaaca ctttgtaagt ataaatttta tgtatgtctt
     1861 cttttttata aaatcatagt gtatcttttt catatattca cattaatttc tatatttcaa
     1921 taacaatatt tccaaagcag aaacttttcg agataattat gtatggatgt aaatcaaagg
     1981 attaaatata ttagggaaaa tatgaatagt tctcaaaaag aattgcttga aaaaacaaat
     2041 ataaatacaa gtgttatgaa tagaatagag tctggtgaaa gaccaacaag agaagatggg
     2101 ttaataatat ttgctaaaat ttttggttta tatactgatt atattcttgg tttatcagat
     2161 acagaaaaac taaatattgg caattaaaac tgaattaatt gtattatatg tgtgatgaat
     2221 ataaatagag aattttttga aaagcttgaa ataacttaga aaaaataaga ggttcactca
     2281 agaacaagtt gctaaagatt aaaaaacaac aaaggtatct actaaaagat atgaaaatag
     2341 tttaagagag ttgagtctgg aaatatttat gtgtattctt taaataaaaa tttatttttt
     2401 aaatgataat taaattttta ctgatatggc tatgctttta aaagtcctaa ccttattttg
     2461 acattatatc tgtctttaca taccacttaa ttaatataaa acagtataaa aattagttac
     2521 agatgtatct tttttgttct ttacatacca cttagttaat ataaaacttt gtggatgtaa
     2581 ggctcaaagt tacgaagaaa aaacctttac ataccactta gttaatataa aacaaatatc
     2641 tctagcaaca tgaagtgact tgccagaacc ctttacatac cacttagtta atataaaaca
     2701 tgagaaacaa aatattaaaa ttgataatat tattgccttt acataccact tagttaatat
     2761 aaaaccagtc caacgttgca cggtcgtaac gtgtcaatcc tactttacat accacttagt
     2821 taatataaaa cgctaaatgg agcaaccgac taagtcgcta gaaatacttt acataccact
     2881 tagttaatat aaaaccggct atgaatttga acatataagg gttacagata agtctttaca
     2941 taccacttag ttaatataaa acttgctgta aggctgttcg ttacagggat ggcagagtcc
     3001 tttacatacc acttagttaa tataaaacaa taacgaagct agaaatcttt attcagcgat
     3061 tacaagcttt acataccact tagttaatat aaaactatgc gtgaaatatt tgtttaggag
     3121 gtttattttt actttacata ccacttagtt aatataaaac tctcatgata tctgtaaact
     3181 tttcccataa ttttcccttt acataccact tagttaatat aaaacataga tgtttcaatt
     3241 tttctttgat attgtaaagc tctttacata ccacttagtt aatataaaac catagttctt
     3301 aagttcttca gaactattca agtgcaactt tacataccac ttagttaata taaaacaaga
     3361 cccaactggt actatgtaaa caatttatcc tctctttaca taccacttag ttaatataaa
     3421 actttaatta tgaatgataa tcatgttaca gagaaacaaa ctttacatac cacttagtta
     3481 atataaaact cacatattct tctatctata tcacttaaca cgtcaaactt tacataccac
     3541 ttagttaata taaaaccaaa tgaatttcta ccaagaatag caggttttat tgcctttaca
     3601 taccacttag ttaatataaa accccaaaat aaattgagta tttccaacac ttacatctat
     3661 acaattctct caaatttgca gtgaaccacg agtagtgcaa atgataatat ttatcatata
     3721 ccctcaatgc cttatgtttc aactgttaag ccctatttta tcaaaaatat cgctcactgc
     3781 aaaactattt ataatattat gaatatatta tttttaaata tctgtaccaa tttgtagtat
     3841 aataaaatca agaaaataat ttactcctat aaagagtgat tatttttaag tgaaaatatt
     3901 atttttttaa atcattctta ttggcgtttg ggagattttt attttatcat aaatataaac
     3961 tgatataaca ccagctgaca tgcttgccac tttagattat tattcttgct acaactatta
     4021 taacatataa aacttactta tttttaccaa atattttatg taaacaataa atattaactt
     4081 ataaaatatc tgctcattta cagatatttc ataagttaat agctctataa taaaattttt
     4141 atcattgttt ataaaaaatt ttactttgca tttttttata aacaacagtt ttatttataa
     4201 tgttttgtgg tataataaaa gcaagaagaa ctacaatcta ttttgcgtta gagtggagtt
     4261 catcataaac agagtttatt ttttggattt aaatataaat ttaaattcaa ctcgtaagtc
     4321 actctttgtg cgagagtggc tttttgcttt tttgaatagt ttactgatta agtaaactac
     4381 cacactagct gttaaactag ctaaaacatt aaacaaaaag ttatccatga actcacctcc
     4441 cttcgaatcg ttgggaggat aatcttttgt acatgaactc cactctatag attgtaagtt
     4501 aaatcttcat cttctgaata attaggttcg taataaaatt tcttcacacc taatagtttt
     4561 ttcactacat tagcagcatc ttctactgta tattctcttc cagtattaga atcgcctata
     4621 ttttttgtta catttaaaca ctgctgtaat atactatcac tcaaatttcc tatagcagtt
     4681 aatttagttg tacttttcaa tacactttta ttactatcat taccaactaa cacaatagca
     4741 ttatttttag caatgttaga accaacaaga gcatacacta aatcagtacc acttgctata
     4801 taaaattctt ttactccact ataaaattta tttattatct ttttgttagt atcatatcta
     4861 tctgtcccac ctaatctagt tgaattagta tccttaacta ttttgtcatt cattgatgaa
     4921 gtaccaccta ttacataact ttctacacca gttgtattaa atggacactt tttccatcag
     4981 ttaatactat agctgcttta tctctaactg ctacaggtgc agcactcatt gcatcaggct
     5041 ctcctttaaa agcattagtc aatatgactt tatttacttt gttaattgag tttatttctt
     5101 ttgcgacatt atagcttgtc ttaattctat cactaccttg aagtctttta atctctattc
     5161 ctttgccttt tagaacagtt tcagtatatt tatcaataga gttttctcct ccaattatat
     5221 atactttttt tgccttttct aatcttttaa gtgtagcatt tggtatgtta tttttcttag
     5281 tcaaaagaat tggagcgttt atagctcctg caagtccact tgcacttaat ccatcagaca
     5341 ttgtactgtc tgcattaatt aatatagctg tagtatagtt ttatttgtct gcaattatac
     5401 cagcagtttc gtatttatct gcacctttaa ttggttcaat tttatcaaga gcatttgcag
     5461 atatagggca actagcaata aatatagata aagataaccc tattgttaat aattttttaa
     5521 ttttcataat atctacttct cttaaatatt ttcacctaaa ttatataata cttttcagga
     5581 aaatgttacc ataaatttaa aaggttatta ttacttaata taatattaat gaaaaatatc
     5641 actcttaaat taatgacttt ggtagaatat ggtgataaaa taaaattaat gagagacaat
     5701 ataaggggga ttatattatg ataatcagta aaaaaataac agcaatatta gtatcatttt
     5761 taattatgat atcaatggtt ggatgtgctc caaaagaaag tgctacagaa gtagctaaaa
     5821 agtaccttga tagtataaaa atcaaagact acgaagtagc atataattta ttaagtaaag
     5881 acagtaagga aaatgtcagt ctagaaaaat ttgaagaata tcaagatact ttatttaaac
     5941 ttcaaaccct aaaagattat aaacttggtg aagaaaataa agtagagaaa tacaaatatt
     6001 ctaataaaga gtacacaaat cttgttaaaa taaaagaaac tgatactata aagtatatca
     6061 ctgaaaataa agaagatact gcaaattttg atagatattt tataatcgaa gataatgaat
     6121 ataaattatt atggcataaa gactttaaaa gagctcttag ctctaattat gtcaaaatcg
     6181 ctaggtcaga aacagaaaaa gatgaagata aggattataa taaagctgct attgatatca
     6241 aaaaagctat agaaattgat gataaaaatc cacttgcata ttatacacaa tcatatattt
     6301 atatagagtt acaacgatat gatgaggctt taaagtcaat tgataaatac ttagaatatc
     6361 tagataaaaa taatgaagct tataaaatag acgctagtga tgcttacaat ttaagaggtg
     6421 ttatttttat gagtaaatca gaatttaata aagctagaga atcttacaat aaggcgcttg
     6481 aacttaaccc ggataatgaa tatgcaaaaa ctaatctaaa tgatattaaa ggattataag
     6541 gcattaatat tatagaaaat aagtatgttg aaagttaaat taacttttga catgcttatt
     6601 ttctatattt taaactctat tgatttacta tataatagtg cataaggagt gtgattactt
     6661 attatgagtg ttgccatata cttaagaaaa tcccgtgctg atgaagaggc agaaaaacaa
     6721 ggcgaatttg aaactttaag tagacataaa tcaaccctac taaaactagc aaaagaacaa
     6781 aacttagatg taattgagat aaaagaagaa ttagtttctg gtgaaagtat aatacataga
     6841 cccaaaatgc ttgaacttct aaaagaagtt gaagaaaata aatatgatgc agtcttagta
     6901 atggacttag acagacttgg tcgtggagac atgaaagacc aaggtatcat attagaaaca
     6961 ttcaaagaaa gtaagaccaa aattatcaca cctagaaaaa catacgacct aacagatgaa
     7021 tttgatgagg agtattcaga atttgaagca tttatggcaa gaaaagaatt aaaacttata
     7081 tcaagaagga tgcaaagagg tagaataaaa tcagttgaag aagggaattt cataggaacc
     7141 tctgctccat ttggatatga tgctgtaaca actggtagaa aagaaagaat acttgtacca
     7201 aataaggatg ctgatgtagt taggactatc tttgacttat atattaatga agatatgggt
     7261 tgtagtaaaa tatcaaaata cctaaataac ttaggcatta aaactgctac aggtgctaat
     7321 tggtacaatt ctgcaattac aaatataata aaaaataagg tatattgtgg ctacattcag
     7381 tggcaaaaaa aggactacaa aaaatctaaa aatccaaata aaataaaaac agttaaacta
     7441 agacctaaag atgaatggat tgaggcaaaa ggaaagcatg aacctttaat aagtgaaata
     7501 acatggaaaa aagctcaaaa tatactcaaa aaaaatggtc atgtcagcta tggtaatcaa
     7561 ataaaaaatc cacttgcagg aatagtgatt tgcaaaaatt gtggtagacc attagtatat
     7621 agaccatatg cagaccacga ctatataatt tgttatcatc ctggttgcaa taaaagttct
     7681 cgatttgaat ttattgaagc tgccatttta aaatctttag aagacactgt aaaaaaatat
     7741 caattaaaag catctgatat agacttagat aaaaataata aagatagtaa tatagaattt
     7801 caaaaacgag tcttaaaggg cttagaaact gaattaaaag aattaggcaa gcaaaaaaat
     7861 aagttatatg atttactaga acgaggaata tatgatgaag atacatttat tgaaaggtcc
     7921 aacaatataa gttcaagaac tgaagaaatt aaagattcaa ttaagacagt aaaaaataga
     7981 ttaagtactg ttaaaaaaga caattctaaa ataatagaag atattaaaac tgtgttatca
     8041 ctttaccatg attcagattc ccttggaaaa aataaactcc taaaatctgt aattgataaa
     8101 gcagtttatt ataagtctaa agaacaaaaa ctagattctt ttgaattaat ggtccatttg
     8161 aaattacatg aagaccagta ataccaataa catataaaga gtagtgtgta atgaaataag
     8221 tcttttagat atacttggta cagaggctaa ctatgttctt gatgaagttg aactaaaagt
     8281 tcaagttgga aaactttacg aacaactaaa caaaattctt actcctagag aaagagaaat
     8341 tgtccagtta agatatgggt taactcctta tggctataag acacaaagag aaattgcaca
     8401 aaaactcgat atatcaaggt catatgtatc tagaatcgaa aaaaaagctc ttaaaaaact
     8461 agaaaaagag cttgttcaag aaagttaata ctatatttta aaaggatata tcgtacatca
     8521 ttagacaaaa ttttctatct aaaatcaaag ttacgatata tccttaaatt ttatagtaca
     8581 taatttattt tatactttca catatttcct taaatatagg tgttgcagat ttatttcctt
     8641 tttgagttcc ttctactaac acagttatta catacttagg tctttcttca ggataaaatc
     8701 ctgttatcca tccatggtct atagcttttt tatttaaact actttgagct gtaccagttt
     8761 taactccaca accaccttca atatctttta ggtctttagc tgtaccaatc ctagatacag
     8821 acttcatata ttctttaact tgtgtacaca cataaggaga aataagttct tctttttttg
     8881 aagacttata agtttttatt gtattcatat tattgtccac aagactttta tataagtata
     8941 gtggtttgaa tgttccatta ttagctatta tttgagtcat ttgatttatt tgaagtggtg
     9001 taaattctat attttcttga cctatagcta aatttcttat tgatatgttt tttggagctt
     9061 ctctaatttt ttcttcatca agaccaatat caaccttttc aaataaatgt aatttttcag
     9121 cagatttgag tatcttttct tttccaagtt tcatagctat atctaaaaat gcaggattgc
     9181 atgaattaga aaaagcttgt cttaagtttt ggaaaccatg accatctctt ttattacatc
     9241 gcagtatttc attagtattc ccaactttag tcttacctgt acagttgtaa gtatagttct
     9301 catctataac accattttca agtgcagaaa ataaaactac catcttaaat acagaccctg
     9361 gtggatatgt cgcttttata actctatttt caaattctcc attttttcct tttaaacttt
     9421 ttgatatgtc attttggtca aaattaggtc tagagcacat tgcaagaatt tcacctgtag
     9481 atgcttccga gattattgct gctgtaggat tttcttcttt atttagtatt tgttctaatt
     9541 ttttttgaat gttataatca atagtagttt ttagatgtct atctttatcc ttattatcaa
     9601 cagtttttac acttcccttt agtatgttta gagatttttc atttcctgca tctccagctt
     9661 taaaagcact tatatacttt tcatttgaat ttctaagtac actatccata ctcttttcaa
     9721 ttcctgattg acctgattta tcatcttctt ttatatatcc tattgtatgt gataataaac
     9781 catcttttgc gtacctcata gttttttctt ctaccattat tccatttttc tcaagttctt
     9841 ttttcatact cttatcgata tttttagtct gaatctgtat tatagggcgt gtcaattgct
     9901 cttgtacagc tttatatata tctaaatcat tcatcttagt agctttctta ataagctcca
     9961 aaattttata gttattattt aatttttctt tttcaacaat taatacctga gatttacttg
    10021 tatctgtaag cttcttgttg tttctatcat agattattcc tcttccacta tttaactcga
    10081 ctttctcaac gctttgtgat tcaacacttt gtttgtattt atcacctttt aatacttgta
    10141 tatcaactag cctataaatt aaaacactat aaattattaa aattatagta aatatacacc
    10201 agcttctctt tcccactttt ttcaaaaatg gagtcttctt ttttgacatg aaatcacccc
    10261 ttagataatt tcattattga caatttctaa ggggctaata ctatttttat caatttttta
    10321 ttattcttca accttttctt ctataacttt tctaagcata taatctttac caacttttac
    10381 tgatagcttt aacttcacta tttgtctagg atgaggagct gattctatag cttctccttc
    10441 ttcattgtac atttcttcaa ttttagtaaa catagtttct ttatatggtc ccataacttc
    10501 tatttcatca ccaacacaca ttttatttct ttgctcaaca acaataagac catcttcatc
    10561 ttctgtttct ctaactatac ctataaaatc atagtttcta acatatgatg ctgattgata
    10621 attttggtct tctgttgttg gtttattcaa gtaaaaacct gatgtaaaat gtctatgact
    10681 accttttttt agttcttcca tccacattgg attgaacttc cagttttctg ggtctctgta
    10741 aaattcatct attgccattc tgtatgctct tacaacagta gctacatagt atgcagtctt
    10801 cattctacct tctattttta aacttgttat accagatttg attaactctg gtatatactc
    10861 tatcatacat aaatcttttg agttaaagaa gaatgtaccc ctttcatctt cgtatattgg
    10921 aaaatactca ccaggtcttt tttcttccac caaatgatat tgccatctac aagattgagc
    10981 acaagaacct ttgtttgcat ctcttccagt catatagttg cttattaaac atctgccaga
    11041 ataagaaata cacatagcac catgcataaa cgcttctata tccatatcta aaggtgtttt
    11101 tgctcttatc tcagatattt catcaaaaga taattctctt gccactacaa ctctttttat
    11161 tccatgctcg taccagaagt ttgcacttag ataattggtt gtatttgctt gtgtacttaa
    11221 atgtatttcc atattcggaa ttactttttt aatgacacta agcactcctg ggtcagctat
    11281 tataactgca tctattccta tctcttctag ttccaacaaa tagtcttcta attgtagaaa
    11341 atcttcatta tgaggtatta tatttactgt tacgaatact ttcttgcctc tttcatgtgc
    11401 aaaagctact ccctctgcca tatcttcctt actaaaattc ttcgctgcag acctcattcc
    11461 aaaaatttct ccacctatat aaacggcatc tgctccatat gttatagcta ttttcaatct
    11521 ctccaaatca ccagctggag ctaaaagttc tactttattt aattccatct acatcacctc
    11581 ttttactttc tttataactt agtgctacac catcacctat tggtaccaat gatgtgctta
    11641 aatagtcaca attacatata taatctaaat aatttctcat tcttttaact atagtctttt
    11701 ttcttcttac aacaaaatca tcatgagcaa ccataccttt atacaaaata ttatcagata
    11761 ctaaaagtcc cccatctttt aatttatcta taactaaatc aaaaaatagc ttatattgac
    11821 ctttggctgc atctataaat ataaggtcaa attcaccttg gacttgacta agtttttctt
    11881 ctgcatctcc ttctagtata gttatgttat tgtcaaatcc agctaatttt atgttttctt
    11941 ttgctttttc tatcattttt tcatttctct caacagttat tatatctgca tcttttccta
    12001 taatagttgc aaaaaaaata gaagaataac caattgcaca tcctacttct aaaattctct
    12061 ttggtttttg aacctttaac aagactttta ataaatctga aacttcttta tgtattatag
    12121 gaacactatt ttcctctgca taaatttcta aatcttttaa aaatccttct ttttctttta
    12181 atgtcactct tatataatct tcaaccaaat cattaactat attactcata aaaacactcc
    12241 ctaaaataat aaatattcaa gttttatatt aatttattat tttttaaatt catattgtta
    12301 tatatattta cactttcttt attataaatc taagaataac aattttcaat aaaaaagccc
    12361 aacattattc ttaccctgtt agacttttta taatcatggt ttattttttt gtattttctt
    12421 tatttgttgc ttttgtatct tttgattgtt tatcccttgc ttctttatat tctttaacgt
    12481 attttaaatg gtcttgatag tttgtactat aattatttcc accatcaatc ttagctacaa
    12541 aatataaata gtctgttttc tctggatata atgctgcttc aatagatttt ataccaggat
    12601 ttgatattgg tgtaggaggt aatcccttat ttttataact attatatggt gaatcaattt
    12661 ttaaatcatc atatgttaca attttctttc tctcttcaaa tatatattgt attgtagcat
    12721 ctgattgaag aggcatacct accttaagtc tattataaaa cacacttgct attataggtc
    12781 tgtctttgtc aagaacagct tctttctcaa ttattgatgc catttccatt acttcttgaa
    12841 gagtcatatt taattctttt tgtttctttt taaacttgtc catgtattta ctgtcaaata
    12901 cttttaacat ttcgcttaaa atatcttctt ctgattgttt ctttgaatta aaataataag
    12961 tttctggata caagaaccct tctaaagagg ttattccatc ttccttcaaa tatggaaatt
    13021 tatcataaaa ttcttgaggt ttttttatta aattttcaaa agtagcttta tctcctaaat
    13081 ttttacttac taacattgct ataatttctt tagatgtagc tccctctgga atagtcactt
    13141 ttataccatc ctgatatatt ttacctgaaa ctaaaagact tattatatca ttgtttgaat
    13201 acgattgatt aagtaagtat gttcctgatt ttatagacgg agctttattg ctaaccttta
    13261 ccaaaagttt aaataatagt tcattcttta ttaatttatt ttcatataat atgtcagata
    13321 tttttccaac agatgctcca cttggaacgt cgataattac atcttttttg ttatttttat
    13381 cataaggacc tatttgtata aacacaaata tacctgctaa gataatcaaa ataacaatta
    13441 ttaatactgc tattttcaat ctattttctt taaagttcat aatataatct actccttatg
    13501 tatatttatc cattttctat tataaaacta gatactttaa ttttcaatca tcttgtagaa
    13561 taaacttatt tatattgtaa aaaatgtttt aaaatatata tttttggtat aatttatagt
    13621 ctatcaaaaa ataaaaaacc taacattatt tttgacatgt taggcctttt ataatcactt
    13681 ttctaaaatt ttctaaaact ttttaatctc ttctttagtt acaataccat atattaattt
    13741 atttttttct atttttgaat ctacaataga gtaggaatca ataaatcttc cctttgccaa
    13801 tgaaagcttt tgttcatcat tataatacat gtaagctaaa acttcacctt catttacata
    13861 atctcctact ttcttttcta aaattatccc tgctgataaa tctaaaatat catctttagt
    13921 ttctctacct gctccaagaa tcatagccga tacaccaaca tcttcagctt taattttgct
    13981 tatataacct gatttagttg atttaactgg atatttatac tttgattttt tgaataaaga
    14041 ataatcatct actacatctt tattaccacc ttgattctct ataaactctt tgagtttttg
    14101 tatagcagta ccagatttta ttgattctct tattttttca acaccatctt caaaatcatg
    14161 tgctaccttt gataaaacca acatatatgc tcctaatact tcgcatagct caacaaggtc
    14221 tttaggtcca tttcctttta atgtctcaat tgcttctata acttctaaag agtttcccac
    14281 tgcaaaacct aaaggttcat ccatatctgt tacaatccct attgtatctc tattcatacc
    14341 agtacctata tcaaccatag atttagctaa ctcaaaagac tcttctaatg tcttcataaa
    14401 tgctccatca ccagttttta catctagcac aattgcatca gctcctgaag ctaacttctt
    14461 agacattaca cttgatgata tcaatgatat attatcaaca gttgctgtaa catctctaag
    14521 agcatatatt ttcttatctg caattgctac ctttgcactt tgaccacaaa ctgctatttt
    14581 agacttattt acagaatcaa taaatttact tatctccatt tctgtcgaaa aacctggtat
    14641 agactccaat ttatcaatag taccaccagt atgaccaaga cctctacctg acatctttgc
    14701 aactggtgct ccacatgaag caaccaaagg tataagagct atggtagtct tatctccaac
    14761 accaccagta ctatgcttat ctacctttat tccatctatc tcagataggt ttatcatgtc
    14821 tccagagttc atcattgctt ctgtaagatg tacagtttcc tgtttattca tcttatttaa
    14881 ataaatcgac attaatagtg cagaagcttg atagtcaggt atatctccct ttgaatagtt
    14941 ttctataaag tagtttatct cttttttact aagctctagg ttatctctct ttttttttat
    15001 aatatcatac attctcataa ttgaaatctc cattctaacc tataataatt taaataaata
    15061 ttaaacttta aaacactttc aaatgttgta gtattataaa aaaactgtcc tttattagaa
    15121 ataactttct atatcaagac agctttttat taattctttt caaattaaac attaactatt
    15181 ttattataaa cttcctcaaa aaatctataa taagctttaa cttataaatt tttaaccgtt
    15241 gttttaacta aattcataaa ttctgattta actttttgag tagtttctat tacttcctca
    15301 tgacttagtg gttgatttaa gatgccagca gccatatttg ttatacaaga tataccaata
    15361 actcctatat tagagtgaga agctactatg acttctggaa cagtagacat acctacagca
    15421 tcagctccca aaatttgtgc cattctcact tctgctggtg tttcatagtt tggaccacta
    15481 aaaaacatat aaacgccttc tttgacatct atattgcatt ctttagcgca gtttttaact
    15541 acatctacat atttagaaga atatgcatct gacatatctg gaaatctagc accaaatctg
    15601 tcatcatttt ttcctactaa tggattactt ccactaaagt ttatatggtc tcttataagc
    15661 atcaaatctc ctgctttaaa ttctttattt acgcctccag cagcgttagt tactataaga
    15721 atctcgactc ctaattcttt cataaccctt actggaaaag tagcttcttt ctgagaatat
    15781 ccttcatagt aatgaaatct accttgcata gcaataactt cttttccttc aagttttcca
    15841 attacaagtt gtccagcatg tcctgctact gttgatacag ggaagtttgg aatttcacta
    15901 tatttaattg cgacagggtc ttctatatca tttgctaaat cacctagtcc agaacctaat
    15961 atcaaaccaa tcttaggttt tatatcactt ttagaattta taaatttact actttgtgct
    16021 atcttttcaa acattccaat ctctccatcc tattaagcta agtttttatc attttatagt
    16081 ttaaaataaa tcttctttaa agcttgaccc atgtttaggc aactttacat ttagtatatc
    16141 tgcaacagtt gctccaatat cagcaaaagt atcttttact cctaaattaa aacctttttt
    16201 aatcttattg ccataaatca taacaggtat atattctctt gtatggtctg tacctttata
    16261 tgttgggtca tttccatggt ctgcattgat tattaaaata tcatcttctc tcatattagc
    16321 cattatttca ggaagtctac tatcaaactc ttcaagagct ttcttatatc cttctgggtc
    16381 tctcctatga ccatatttag aatcaaaatc aacgagattt gaatatatta gacctttatt
    16441 atcttgtttc atataattta aagtttcatc cactccatcc atattgcttt tagtgtggat
    16501 agcatctgta attccttttc cattaaaaat atcttctatt tttccaactg ctaaaacatc
    16561 aagtcctgat tcttttatat tatcaagaac tgttggttca aatgggtcta gtgaataatc
    16621 tcttctattt gaagtcctca caaactcacc ttttttctta cctatgaatg gtctagcaat
    16681 tactctagct actgcattat cccccatcat tatttcccta gcgattttgc acatattata
    16741 gagttcttct aggggaatta cttcttcatt agcagcaatc tgaaatacac tatcagctga
    16801 tgtatatact attacatctc cagtttttat ttgatgttct ccatactcat ctattattac
    16861 agttcctgaa gctggtttat ttcctactac ttttcttcca gtttttttct caaactcttc
    16921 tattatctcc ttagagaatc catgttcaaa tgtcttaaat ggtttgtcaa ctattatacc
    16981 agtcatttcc caatgacctg tagtagtatc ttttccctga gacatttcct tacactttcc
    17041 aaaacaacct attggttctt ttatactttc aaaaaaatct ataccatcta tgtttcctat
    17101 acctaaattt ctcatattag gaatctgaat atctggatat tccttaaata tatttccaag
    17161 ggtacttaca tccttactat caccaaattt ttcagcatca ggcaatgctc ctatcccaac
    17221 actatcaatt acaatccaaa ttactctgct catataaata tgctccttct aaattataaa
    17281 atttgctata tagtctattt agcttctgct ttttgtaatt ctacatcaac atcatttcta
    17341 ggatgtttct cctttatttc tcttctcacg tttttatcta tatgatttaa atatacttgc
    17401 aaactagata aattaacatt tcctaaaatt ttacttacaa cagcaatgtt agcaccttca
    17461 tttaacaaat gaatagcaaa tgaatgtcta agcattgtag gatttatatt tttatctata
    17521 ttggctagat tagaatattt ttttatgact ttccaaagac cttgtcgtgt aaacctttga
    17581 cctaatgaac ttacgaataa tgatttttca ccttctacag ccattttagg tcttgcttct
    17641 tttagatact tttctaagta aagttttgta atatcacaaa gtggtatcac tctttgattt
    17701 ttacaacatg aattacaata tatataatca atatctaggt caatatcctc tatattcatc
    17761 tctactaatt cagatacttt tataccagta ccatataata cttcaaaaat agccttgtcc
    17821 ctaatcaatt taggtgttgt taactttgga aaatttaata gtctttcaat ttcttcttct
    17881 gtaagtatat ttatattttc tttttttatt ttaggttttt ttatatcctt tgcaggatta
    17941 tttgtacata tatgatttaa aaataaataa tcatgaaaag attttataga ggatatcatc
    18001 ctcgctattg tagctattga tacattatct ttttccaact ttattaagta acttataata
    18061 tcattttcta ctatatctac tagtttaatg cttttttgat ttatatattc catatatttt
    18121 tttatatcca taaagtatga tgccactgta ttctctgata attttttttt atcttttatg
    18181 taatctatat atccctctat aatatccatt ataaactcct ttatttagct aggaacttaa
    18241 taataccaat acttgcagta tttaatatta attgcaaccc caatgatagt gctattataa
    18301 ttataatatt tagtatatac ctcttaatta aaaattgcat attttttcta tttttctttt
    18361 taaattcata aaccatttct ttaaaataac ttaaactaat taatgctaat atgattgcac
    18421 atggaataat aatcaaattt ttaaataata ttattaaaat catttttata cttttaaatt
    18481 ttaatgccaa tatacaacta tttattgtat aaccaattga catccctttt aatacaaaag
    18541 ctaccaacac tgctggaatt gttactacaa atagacttaa tagagctatt gagcccataa
    18601 agattgcatc tgattttaaa ttttgtatca ctgtatcttt tatgcttata tttagattat
    18661 aatactctac agcaggattt atattgttta atatattgtt actagaacct ggcaatattt
    18721 tatttatgta agacccaaca acaatagaca tcataaacaa caatcctata ataattattt
    18781 gtctatttaa ttctctaaaa tcattttttc tatatgttct tctcaattta attccccctt
    18841 gtcctttata aaataatatg ctttaggaca aagggttatt cattttataa atattaattt
    18901 ttaaacatat cttttactaa taataatcca atagatgttt ttgcatcttc aacgtcattt
    18961 tttaatacca tgttatatgc ttcttcaagc tcaatttcat agacatctaa aaactcatct
    19021 gcatctaaat tattctctcc tggagtaaga cctgttgcta aatatacaaa cattatctca
    19081 ttagaaaaac ctgctgaagt gaaaaattta tgtattagct taatattttt tgcactatac
    19141 cctgtttctt cttttaattc tctttcagca cattcttttg gactttcatt tttttctagt
    19201 ttaccagctg gaatttcaaa gattggcttt tctataggtt ttctaaattg cttaactaac
    19261 acaactttat tatcatctgt gattgcaact attcctactg ctccaccaac ttctactaac
    19321 tccctttttt gatatccttg ccctggaatt tcaacagtat caacctttaa agtaattact
    19381 ttacctgtat aaaccctatc actactaata gttttttctt ctaataccat cttaaacctc
    19441 cattaagtaa tatgctgctg tgcttgcagc tttgaaaaat gcctcatctt gttcataatt
    19501 tcttcccata ctctttactt ttagattaaa atagtctaaa tcctctttcg ttttattatt
    19561 atctatataa attatattat gctttttgtc taaaccattt aaattgattt gctcttttat
    19621 aaagttcaat ttttcatcat catatatagt tattggtatg tctacattta catttacaat
    19681 ttctttaaat acagtcatac tatgatgtga aataccttga tgtctttctc gtttgtcagc
    19741 aaaactaatt cttggaattg caattgctct tccttcaagt ttttttacag catcaagaat
    19801 agagccttgt tcaatccctg taaatccata ttttgttcct gtcccagcaa ttccaggtcc
    19861 catactgaca aatactgcat ccgcttttag tatttctttt gctgtaatta atgcagtata
    19921 tatatttata cattcataat ctccaccaaa cgcatttcct atagttattg tactatctat
    19981 taattttttt tcttttaaag tatccacatt tttacttaaa taaattggaa gagatgctcc
    20041 atcagtcatt atatacacta attttttatt tggattattt cttttaaatg aagctgcaaa
    20101 tggagttaac atactatgaa gagtccctac tacaacagaa agaccttcta atcctttaaa
    20161 attcgcaaat ttatcatgat aaatactttc ttgttcctca acagaatcca cttttatttg
    20221 aagaggcgta tatctaagtt tcattatatg tccaccttca gttaaagtag attctatatt
    20281 atttaaatta gttattacaa aatggtatcc acctgtacct aagctcagtt ctactgctgt
    20341 tgtatttaaa accacttcgt cacctatatt tatagttcca gatattttgg gataattata
    20401 tgccctttgt atttctccat ttatatttac tcttatatca tctagtgttt cagtttgact
    20461 tactattgat tcaacaatcc ccactctttt gcttatcata atactacctt cccaatttat
    20521 ctataaaatt taatagttta tttttttcta ttatcttagt taatgagtat ttctcagtga
    20581 atatatgcat aataactaca aatattaacc atcctaatct aatgttaaat ggatacccaa
    20641 aagaaatgag cattccaata gatattccaa ggacgtttga accagtatct cccatcatag
    20701 cccttgcttt taaatcataa ttaaagtatg caagtacatt tggtactata agtaatggaa
    20761 gaacttgaac aaatcctgtc aatgttaaaa atataattac cattatgaat aaatatgctt
    20821 ttattgccct tcctggtctt aaatccaaaa gattcattaa attagttgat agagctatta
    20881 ttagtgtatt tactattata tcaattatgt cttttgatat agcaacagaa actataagcc
    20941 ctacaaatcc accaaataaa gctttaaaac ctcctgttgt aagacttcct ttaaataaac
    21001 ttttaaaatg cccctttaaa ccacttacat ctctatttcc aatgacatca tctagtatcc
    21061 ctgcaaaaaa catggatatc ataccaaaca taaacataaa tatatacgct aaatccttaa
    21121 attctgtagt aaagaaagca agtattattc cattgattac aatcataggc aaaaatacaa
    21181 ttcccatact tactggtatc atatcttttt tatagtttgg tctaagtaca tttccattta
    21241 tcaataaatt tttaaatagt ggaattacag cataggttcc aaataatcca gttaataata
    21301 aaatggtata aagtatataa tctttcacta agatattacc tccattcttt ctttttttgt
    21361 cctaaaacct tttttatgtg ataatactgt ttccctctat gaataaaacc ttttaaattt
    21421 cttcctgttt cattatgagt catatttact aatacttctt taattttaaa tccatacttt
    21481 aatatatcaa tggtcattcc aacttctact ccatatccaa aaggtatttc atcaaacttt
    21541 tctaaaactt ctcttttaaa tattctttga cctgataaag ttgcatctaa ctcaacacca
    21601 gtcatctcaa acacagaatt tttagctaaa ccttttacaa atcccaaacc tccttttctc
    21661 tttgcaggag gaaacttggc tattgtaaca tccgcctcac catttaatat aggtactatt
    21721 aatttttcaa cttctttagc agaacttcct aaatctccat ccagaaaacc tataatatct
    21781 gcatttttca ttgctaattt gataccataa tttaaagcat atcctttacc tctattttta
    21841 tctaacttaa aaaatttaat cttttcattt tctagctcag atacaacctt agcagtattg
    21901 tcaattgaac catcatccac aactattatt tcatttattt gcttaatgtc caatatgctt
    21961 tctaatgtat attttattct actttcttca ttataagctg gtattattat acttatataa
    22021 gaatccattt tttctctcct taaaattatt tctatttaat agatggcaac aatgaagttg
    22081 cagtatccaa tctaccaaaa ttaccaacta tattaccttg ttgtagaaga atagctagag
    22141 atatacttcc tataccttca tcaatattgt ctatagttgc aactttgttt ttagaatata
    22201 gttctacata agaagtttta actcctgtat tttgaacttc tactaaatat ttattctctg
    22261 atttaagttt tgaaactaca aatttttcta ttttttcaaa ctgttttgta ctgtcttttg
    22321 catcatttcc accagctatt acaacggaat catattttag atatgtatct ccaataaaat
    22381 taaactttat tacatctagt tcttgaagat atgttaaaat gtcacttgca tcttcctttt
    22441 taagagtgtc aattatataa ttaactgcat catttgcatt ttttacatct gtacctagtt
    22501 tagttgacat ttcctttaac ttttctggat ttgttatgtt ttcttttaat attatattaa
    22561 atgcaatgct tccattagat ttatttatta tgtcttctat attttttgta taatcgtcat
    22621 tttcattagc agatattatt cctatacttt taccattcag cgaaccagct aaaatcttat
    22681 ctacattttt atttataaaa ttaactgcct cttcataatc tctatttaca cttgctaagt
    22741 cactgtcaag tttatcattt ttttctttta agatatcaaa cttatcatcc aaatcattta
    22801 ttatgtttgc ttgttgttca cttaattgtt gattattatt taaattaaat cctactaaca
    22861 tgcctatacc caaagctata aatatagccc ctatagtgac tatataatat ttcatattaa
    22921 tatgcatatt tatcctccta aaatttacat ctgtaataat actctaaact ttaattgcat
    22981 tagttgtatg aactgttgaa ctcctggtga caatgatgca actaccaaca caggaaataa
    23041 tgctgttgct attaatgccc atatgtactt tatttttaat ttacttctgt ataacaaatt
    23101 aacgccttta gcatctataa gctttgaacc tatttttagt ctaactaaaa aagtacttgc
    23161 catacctttt cttccttttt caagaaaatc aatcatattt gaatgtgtac caactgctac
    23221 tattaactca gccttatact cataagcgat aagcatagct atatcttcac tagttcctgg
    23281 tgcaggaaat acaactgcat ctaagcctaa ttcctcaacc cttttaagac ctggtgctct
    23341 tccatctgta taagcatgta ctactatttc actagccttt tttaaagctt catcacttac
    23401 actatccata tcacctacaa tcacatctgg agtatatcca aactcaatta aagcgtctgc
    23461 tcctccatca acaccaacca atactggctt tacctcttct atataagaaa gcatagtact
    23521 taaatcttct ttgtagtcct gacctcttac aactatcaat acatgtttat tagcataatt
    23581 agttttcact tttggaattt ctacttctcc aagtataaat cctttttctt ttttagcata
    23641 atctatagta ttatctataa atctatccaa ttctacagct aaattctcat aggcagcctt
    23701 tatttggtgt gaaacctcat acttgtctaa aacttctcct gcacctaaaa attttccttt
    23761 tctatatatc tttccatcta caacttctat agtttctcct tcttttaatt cttcaaataa
    23821 ctcttctcca acattatcaa ttattagtat attattttca gttaatatcc ctggaccttt
    23881 attgggatac ctaccactta tagaaggagc cgcatttatg acaagtttta ttttagcttc
    23941 tactaaagag tttgcagcaa cttcatctat gtctatatga tttataactg ctatttcccc
    24001 actttcaact cttttagcaa gttttttggt ttttcgatct acttttatag gggcctcgac
    24061 tctcatattt aaacctccac tatcattatt aaaatcacat tatattatag cattacttaa
    24121 caataaaata aatgttttaa gtttgttttg catctttggc atttacaata ctatatttca
    24181 tcattttttt atttaacata ttccataata cgcttaaaaa tacaaagttt acctgcatca
    24241 aagtcaatat ttatattaaa aaataaacca ctgtcagttt acaacttgta aagacacata
    24301 ctatatccat agtataataa aattattata ttgatatagt aagcaaataa taaataaaat
    24361 ttttatattt attaaaatag cgaaacggta taaccctagt ggttataccg tttcgctgct
    24421 tgtaatacgc atttatagcc aatgccttaa ttaaaaagcc ttacttttta tgtcttgttt
    24481 atttaaccat actatgttct agtcttaatt tatcagcaat cattgctata aattctgaat
    24541 tagttggttt tcctttagta ttgtgtaccg tatatccaaa taattgattt attgtgtcaa
    24601 cttttcctct actccatgca acctctattg catgtcttat tgctctttca actctacttg
    24661 gtgttgtatt gaatttttta gctatacttg gatataactc ttttgttact gcacctaaaa
    24721 gctcaacatt atcaataacc atttttattg cttctcttaa atataaatat ccttttatat
    24781 gagctggtac tcctatttca tgtattatat ttgtgatttc tgtctctata tttcctacat
    24841 tcttaacaaa atcacttcta gtcatttgag tctcttgaac tggtctaggt tttggctcaa
    24901 cttgtgtaac tctattagaa actagctctc taattctgtt tataaacaca acaaaatcaa
    24961 atggctttac tatgtagtaa tctgctccta gatttattgc gctttgagtt atcttatctt
    25021 gacctactgc tgatagtact attatttttg gcattttagg tatatccata gtattcaatt
    25081 tttcaattac acctaatcca tctagatgtg gcattattac atctagtatt aataagtccg
    25141 gttgtgtctt ttttactaag tctaatgctt caattccatc cttagctatg cctaatatat
    25201 cgatatcatc ttcattagac aaatactctt ttaatacctg acaaaaatcc ttattgtcat
    25261 ctgctaaaac tattttgatt ttttccacta aaaatccccc cattaaaaaa catcttctta
    25321 ttacagaaaa ctaaactttt tacacaattg cttcctaatt atctactcta aagcatattc
    25381 gacactccaa aattatattc ctcctagata attgataaaa taataaaatt ttttaatgcc
    25441 tcacctacaa ttttatcatt tcatctataa aaataccata tccttttttc ggattatctc
    25501 taaaaacatg agttattgca ccaataattt tattattttg tattattgga gctccactca
    25561 tcccctgtac gatacctcct gtgtattcca ataacttgtc atctactact tttattacca
    25621 tatctctata atttccttta tcatatacta tactttctat ttttatatca tagcttgtta
    25681 tatttttgtt tttatcctca aaaagaatta ctgcacctcc tatttttaca tcttgcggtc
    25741 ttccaacttc tattaattgc ttttctttat ttgctacatt aaactcttta ttatggtttt
    25801 ctgtaatatt accacttata cctaactctg aattatttga gaaattaccc attaaattgc
    25861 tgtcattaaa atctcctttt attttaccta ctttttcatt actagctttt actattttta
    25921 attgttctgg cttatatata tatccttgct ttatctttaa tagttcatta gtatccgaat
    25981 cttttatggc atgaccaatt gctttgaact tttccatact agggtcgtaa aaagtcatag
    26041 ttccaattcc agatatttta tctcttaccc ataatccaag tttatacttg ccattttctt
    26101 ttttagtctc tattacttct gttttatact tattttttct ctcaaaagtc acttcaactt
    26161 tacttttttt aatcttattc aaaatctctg atacatcttg actatttttt atccttttat
    26221 tatctatttt tactatatta tcaccgattt gtatgcctcc aatatagtct acatcctctt
    26281 cctcatatcc taagaccaat acaccatctg tatttgcttt tactccaatt atatttccca
    26341 taggatatac aaatttttta tcatgattct taattgtaaa agcttctatt tgagtctctt
    26401 tattaacatt acaattttta ttaaaaatta taaccatggt aaaaatcgat acagctccta
    26461 atattatcca aatatttttg aaatttttat ttattttgtt catatatcca tctactccta
    26521 tgctgtatta ttatgtattt ataattcctt tttcctgaga atttattcat ttaaaaagtt
    26581 tatttaaaat cttaataagt gatttttaat acataatatg atagtattag attgtaacaa
    26641 aaagtttgaa gggcggtaat atcttgaaat taaatgtaag aattgcagac ataaataatt
    26701 ggcatgattt agttagtttg tctgtagata aaagtcagtt agattatata gaaagcaatg
    26761 cactttctat tgctgaatct aaatttataa cagcttgggt acctgttgga atatatgatg
    26821 aaaattcttt aataggattt gctatgtatg gtcgtttaga agatgataga gtttggcttg
    26881 atagatttat gattgattca aaatatcaag gtaaaggata tggaaaagca tcattagatt
    26941 ttcttgtaaa tcatcttaaa aatgaatata actgtgatga actatatctt agtatattcg
    27001 aagacaataa aatggctatt aagctttata aagattttgg atttgagttt aatggagagc
    27061 ttgactatgg tggtgaaaaa gtaatggtat taaaatctaa ttgatattaa gaaaaatata
    27121 catatatcaa ggaggtgaag tcattatata aacatgtgta tataatggcg gataaaatgg
    27181 ctcaaaatat aactttacaa tttgttgaag aaaaagattt agaaaacctt gaaaacgtaa
    27241 aacttctatt tactgaatat tcaaattctc taaatataga cttatgtttt caagacttta
    27301 ataatgaatt aaaaacactt ccaggaaaat ataaaaaacc ttcaggctca ttgatattgg
    27361 catttgttga tgaaaatttg gcaggttgtg ttgctttaaa aaaacttgaa ggtaaaatat
    27421 gtgaattaaa aagattatat gtaagaaatc aatttagagg attaaaaata ggaaaaatac
    27481 tattggaaga aatcattgaa gaagctaaaa aatttggata tacacacatg agattagata
    27541 ctcttccaag catgaaaagt gcacaaggat tatacgaaaa gtttggtttt tatgatatag
    27601 aaccttatac ttataatcca attgaagggg ctagatatat ggaattaaaa ttataatttt
    27661 ttaatagagt ataagtaaaa ctactacagt tttatttata ctctatttta ttgaacaaat
    27721 ctatttgaat atttatttaa atatgtattt atttttctaa atcttgtaat cccatagtta
    27781 tatcttcagt tatatccttt gtatattcta ctccattatt gtatgtaagt ttagctttaa
    27841 tataaattat gtcatcaata tcccttttag gaaaacttac ttcataattc acttgatttc
    27901 tatttgaatt attagttttg ccatcatcta agccttcagc taatttggct ttgtatatag
    27961 tgtctttttt tccttcattt acaataatat ctactttttc taatctaata ttatcataaa
    28021 ctttattttt tgacttttca ctctcatgat tgaaaagatt actattttct actatttcaa
    28081 taaagtattc tctattatct cttatcccag aattaaatat gggttgttca ggcatataat
    28141 cagatttagt caatttttgc acatcagaac tttcagatat agctccactt gtaactactt
    28201 tatagtcata ttcacttcct gtatttatct taatttcaca tgcatatgat aattctccat
    28261 gttttgtcat ctcagtttca ttccatttat cactatcttc tttatacata aaaaatactt
    28321 ttccattttt tccaagttta cttaattgaa catctatatc aataatacat tcttttttct
    28381 cgattttttt cacttttaag tcaatacttt ttgttatata gctttttgac atttcttcat
    28441 ttatagtatt actaatatcc gacttagtac tcataagctc ttgtgacaaa taatctaatt
    28501 tgttactaca actttcaata tttttattaa tctcacttac tgctaccaca atataccata
    28561 ataaaataaa aattacaatt ataaaaatta agtgcatagt atctttttta ttcattttat
    28621 gcctcccctc actactacct taataaataa tattatactt aagcatttag aaatttcaaa
    28681 gttacaaatt tatacaaagt tcattccatt ttcaaaccta cttttcttca atataggcac
    28741 tagatatttt aaaataattt catcataaaa aatagatgta aagcatttct ataaaaattc
    28801 tttacaccta ttaaaatgct tgtttttcac taacattttt tagccaactc aataatttca
    28861 cttgcatgtt caatagtttt ttctgttata ttgttacctg ctataagtct ggcaatttca
    28921 ttttttcgtt gagattcatt taacttacta acattggtaa acgtcctatt atttgaagta
    28981 tctttctcta tacaataatg agtgtctgca tttgcagcaa tttgaggtaa atgagttata
    29041 catattatct gttttttctt tgctatatca ctcaatttct caccaactat ctgtgctgct
    29101 atcccactta ttccagtatc tatctcgtca aacactaatg tatcaatatc atctatatca
    29161 gccaatatgg ttttaaacgc taacataaat ctggacatct caccacctga tgcaacttta
    29221 tatataggct taatatcttc tcctaagtta aaagatatca taaattcaat atcatctact
    29281 ccatctaaag taaatggacc tttttcaaaa ttaaccttga acattacatt tttcatattt
    29341 aagcttttta attcatcaag aagtattttt tctaaagtag ttgctacttc tattcttgct
    29401 ttagtcaatt tactggcttt tatttttaaa tcttcttcta tattcatcag tttgcttctt
    29461 aactgttcaa ctctttcatc tctgtttaat atttcatcta atctatcttt aatttttcca
    29521 taatactcaa atatatcatc tatactgtct ccatattttc ttcttaagtt attaatctcg
    29581 tcgattctaa gctcaatctg ctctagctca taaggttcaa agtctatatt atctttgtaa
    29641 tttcttatct caccagatat gtcttgtaac tcatacatga ttctttctac agtatcacta
    29701 tattcactta aaacactgtc atatttagat atgtcattaa gttccttaga tgcaagacct
    29761 attaggtcaa taacattata ctcaccatta tgtaacttgc tataactcga atttagatta
    29821 ttatatatct tttcactatt tctataaact tctctttgtt ttaataaatc ttcatattca
    29881 ttcttattta gatttgcagc ttcaatttca tttatttgaa atcttaataa atctatttct
    29941 cgttgaattt gcatctcatc tttattttct gtcaagcaat ttaaagcttt ttttacttca
    30001 ctatacttat ggtacacatt tttataagca attttaaact cttccaattc attttctcca
    30061 aaaaggtcta gaaattttaa atgagtatct ttattaaaca aagcttgatt ttgatgttga
    30121 ccatgtatat ctataagtgt agatgcaatt tctttaagaa gagacacttt aacagtcctt
    30181 ccatttactc tagcagtact cttaccatct gagtatatca acctagttat taccaataaa
    30241 ttatcatctt ccatacttat atcattttct tctaatattt ttttaagata tctattgtct
    30301 gaaaaaaata cagcctcaac aagtccctta tctgttcctt ttcttaaaaa agacctatca
    30361 tatttatcac ctaaacaaag tccaagtgca tctattatta tagattttcc tgaaccagtt
    30421 tcacctgtaa gtatatttaa gtttttatca atattcaacc ttagttcttc aactaaggca
    30481 caatttttca tatataattc gaggatcaaa tctaagcccc cttttaacct atttgtctaa
    30541 attatgagaa gcttcaacaa cttctactat tttgttattg tatgtctcac catcaaattc
    30601 atatccttca tttccatttc tcaaatgaat tagatattct atattacctt caggaccttt
    30661 aataggagaa aaatctaacc ctaaaatctc aaatccattt tcgactgaga aatcagaaat
    30721 catttttata acttctatat gtgtagattt ttctctaact actccttttt tacctacttt
    30781 ttctcttcct gcttcaaatt gaggtttaat taaagcgaca acttccccat catgacgtac
    30841 taactccttt gcctttggaa gtactaactt taacgatata aaagacacat caattgacgc
    30901 aaaatcagca aactgctttg tatcttctat tgtcacattt cttatattgg ttctttccat
    30961 acacacaacc ctatcatctt gtctcaattt ccatgcaagt tgaccataac caacatctat
    31021 agaaaatact tttattgctc catttttgag catacaatct gtaaaaccac ctgtggatgc
    31081 ccctatatcc atacatacct ttccatcaat agtcaaatca aagtttttca ttgctttttc
    31141 aagctttaaa ccacctctac tgacatatgg tattggattt ccttttactt ctatactaca
    31201 atcttctttt acttctgtac cagccttatc acacctttga ttatcaacaa aaaccaatcc
    31261 agccattatt gcttttttgg ctctttctct actttcaaag tacccttgtt ctactaataa
    31321 taaatctatt ctttttttca tacaattacc tttctgttaa aagctacttt aatgataact
    31381 aaagtagctt gaagtaacac acttgatatt tattctaatt gataaattct atattttata
    31441 taaattttaa tttacaatat ctacattaga tttttactca ataactaatt tccttatctt
    31501 atcagcaata ctttttggcg ataatcctac aaagtcatat aattcatcta tattgccatg
    31561 ttttacaaat tcttctggta ttgctatatt aagtatattt acgttatatt cattatctat
    31621 aataaactta tttattctac ttccaaatcc tccagttaca atattatcct ctatagtaac
    31681 tacattttta tgatttttta ataatgcttt taacatacct tcatcaattg gctttaagaa
    31741 tctagcatta actattgtcg gatttattcc ttctcttgat aatatttctt tagcctctaa
    31801 agcatgtttt accatacttc caatacaaag tatgactgta tcttgaccgt catctaatac
    31861 ctcatattta cccagtacaa tctctccata ctctccctta tctaggtaat aactacttcc
    31921 tcttgggtat ctaattgcta gtggacaatc taattttaat gacaaatcca tcataagctc
    31981 catctctctt gtgtcttttg gagccattac tacaatattt ggaatagaat ttaagtaact
    32041 taaatcaaac ataccatgat gagtttctcc atcatttcca actaatccag ctctatctat
    32101 aagaaaagta actggctttt ttgttatgca tacatcatga ataacttggt catatgccct
    32161 ttgcaaaaat gatgagtaca cagcaaagta aggtttcata ccattttttg caagacctgc
    32221 tgcaaatcct gttgcatgtt gttcagctat accaacatca taatatcttt ttggatatgc
    32281 actttcaaac aggtttaacc ctgtaccaga tggcattgca gctgttattg ctactatatt
    32341 ttcattacta ttagccatat caacaagttt ttctccaaca ctaattgaca tagacttaac
    32401 ttttgcagat gtaacacctg tctttatatc aaactttgat actccatgat atttatcagg
    32461 ttgttcttct gcaaatctgt acccttttcc ttttttcgta attacatgta aaagaacagg
    32521 cccttttttg tgtttagctt ttctcaatat atctattagt tctttagtat tatggccatc
    32581 tataggtcca taatatctta tacctaatga atcaaaaaat gaacagtcct gaggagaaaa
    32641 gctatacatt agtttatctt taaatctatg tgcagtctta gataaaattt cacctgtttg
    32701 tgtaacattt aaaattttat caacttcatc tgtcattttc tcaactgttg agtttcttat
    32761 aatacttgac agatatttag acattcctcc aacattttta tctatggaca tctcattatc
    32821 attaaggatt actatcatat tggtatctat atatcctaat tgatttaaag cttcaagtgc
    32881 catacctcct gttatagaac catctcctat cacagatata acactatagt tttctttttt
    32941 tatatcccta gcacaggcaa tacctgtagc tatagaaata gatgtactgc tatgtcctgt
    33001 atcaaaaata tcatgaggac tttcattctc ctttggaaaa ccacttagtc cattaaactg
    33061 tctcaaagat acaaaacaat cttttcttcc agtaactatt ttatgaacat aagattgatg
    33121 ccctacatcc catacaatct tatctttagg gctatcaaat actttatgaa gtgctaatgt
    33181 taactcaacc actcctagat tagaagctaa gtgtcctcct gtctttgaaa cagattttac
    33241 taagaacttt cttatatcct ttgcaagtaa atccatttct tctatactca tattttttat
    33301 atcctttgga gaatttactt tatctaaata tttatacata ttatcctcac ctttattctg
    33361 taaattttca atttacatca atattaaagc tgttactatt ccaagtaaag ctccaaacca
    33421 aacttctagt ggtgtatgac ctattaattc ttttaatttc ttctgctcta tatgctttcc
    33481 atgctgtata tctgccacca tttgatttaa tatagtagct tgtttaccaa cagcccgtct
    33541 aacacctgct gcatcataca ttataattaa ggcaagcacg gtaattatag caaaatcagt
    33601 agaattaaac cctttttcaa tacctaccac tgtagctaaa cttgtaacaa aagaactatg
    33661 ggaactaggc atacctcctg aaataagtat tcttgataac tcaattcttt tttccttacc
    33721 agtaaatatt tttataaatt gtgctaagaa acaagcaatc agacttattc ccaaagcccc
    33781 attgttaaaa atctccgaaa aaaaatccat ttttccctcc tcgattttag ctgtatattt
    33841 tagtattctc tatctattat atattcagcc aatcccttta aaaaatctac atcatcagat
    33901 aatttttcta tacttttctt tgcttcatca atcaaattat gtgcaatttc tttagattta
    33961 tctaaaccta aaagagatgg gtatgttgac ttatgatttt ctatatcact tccaaccttt
    34021 ttacctaact tagcttcatc tcctactatg tctagtatat catctactat ctggaatgat
    34081 aatccgatat tttttgcata tttagttatt tcttccattt gttcagaatt tgctccacct
    34141 atagtagctc ctgctctcat acagcctacc atcattgcag cagttttatt catatgtata
    34201 taatctaatt tttctttttc aatttgttta ttttcgcttt ctacatctac tacttgacca
    34261 cctatcattc catatatacc agcacctttg gcaatttcat ttatagcttt tagatacttt
    34321 tctggatttt ctttattgat tgagcctgca agcattactt caaaagcata gtttaacaaa
    34381 gcatctcctg ctaaaatccc catagcttct ccatatactt tatgatttgt tggtcttcct
    34441 cttcttaaat catcattatc aagagctggc aaatcatcat gtattagtga atatgtatgt
    34501 atcatttcaa ttgcaatagc aaaaggaata gcttcatctt cattacctcc aactatttta
    34561 caagcctcca atgtaagtat tggtcttaat cttttacctc cagcacttaa gctatagttc
    34621 atagcttcaa taacagtttt ttgataccct tcttctttag gcatatattc tttaagtact
    34681 ttttctacaa aacttgcttt ttcttttaga cattgtttaa attccaattt tattcctcct
    34741 ctattttaaa gtcttcttct attcccaatt gattaaattt acttattttc aatttagcat
    34801 catctaaaag cttattacaa tgtttataaa ggcttatacc ttcttcatat aggcttaaag
    34861 attcatccaa gctagcattt ttagattcta attcacttaa aatactttct aatcttttat
    34921 aagcttcttc gtaggttaaa ttcatactat ccctctttat tttcaatttt atctatcata
    34981 cattctaaat ttccatcttt taatactata tctatactat cctttatttt taatcctttt
    35041 atactattta ttacttttcc atttttttga gttatactat aacctctatc catagtagct
    35101 aatggactta aattatggag taatgctcca atttttacta atttttcatc ttctaatttt
    35161 aaattatttt ctattccaaa aattatttta tcatatattt tgtctaattg tataacttta
    35221 tcttttattg tgtacgaatc taaatagtta tttatcttat taaatactgt ttctaaccta
    35281 tattggtcta gctctatttg atttgtaaga gacttactca tcctactttt tatgtttcca
    35341 agtttatagt ttatatcatc caatgatgga gtagcaatct cagctgctgc tgatggcgtt
    35401 ggggctctca tatcagacac aaagtcacaa atagtaaaat ccgtttcatg cccaactgct
    35461 gatattatcg gaatttgaga attaaaaacc tctcttgcta ccatttcatc attaaaagac
    35521 caaagttctt ctattgaacc cccacctcta ccaactataa gtgtatcaac attcttcata
    35581 tgattgaaaa atctaattgc ttcacagatt tcttcagctg atttatctcc ttgaaccgtt
    35641 actggataaa gctttatatt aactttcgga tatcttcttt ttattacatt tattatatct
    35701 cttataacag cacctgttgg agatgttata acgccaattg agtttggcat tttaggtata
    35761 ggtatcttgt atttagggtc aaataatcct tctttattaa gtttttcctt taatctatta
    35821 aactctatgt gcaaatttcc tattccctct atttcaattt cattaatgta taattgatac
    35881 gcaccatctc tttcatagac tgatatatat ccattagcta taatttttac accattatct
    35941 aattttaaat tgcgattaaa attactttta aaaattacac agtttaactt tgatgtttca
    36001 tctttaagtg ataaatatac attcccacta ctatgaacct taaaattaga aatttctcct
    36061 ttaactttaa gattagaaag tattgggtcg tttattaaaa ttcttttaat atatgagttt
    36121 gcttcactta tatctaaagc tcttagtttc atactctttc tcctaaaaag ttattcaatc
    36181 ctattatagc acacccgaca gcattatcag ttgaatattg tggttctgta aaataagctt
    36241 ctatatgctt ttttcttaac ttcatgctta attctctaag aatatactta cttgcagaaa
    36301 ctccaccagc aaatactact tcatttacat tataagtttc acataaatac actagagatt
    36361 taaacatatt tctaactact gaatctaata ctaatttaga tatatattct ttttgattag
    36421 tattatctcc attatcattt ataatcttat ttacctgatt ttctaatcct gataaattca
    36481 tatacccatc tcttacagaa gttttcagac cactttctat tttaagatta caatttaaag
    36541 cattttcatc caaatacttt cctgaaggaa atttatatcc aagcttaatt cctactctat
    36601 ctataagttg accaaagcta atatctttac ttcctccaat tatatctata ttatatccaa
    36661 aattattgta taacttactt ttatcatctt ttttaatact tattttggca attttaccta
    36721 aattagtatc acatacattg tgatgactat cttgtttgct tgttaaaagt atctctgtag
    36781 taccaccaga catatgaaca gaaataaatt tattattatt ttttaattta ctatttaata
    36841 aacttgcttc aatatgattc tcttgatgag tagtctcata aaatctacaa ccatatatac
    36901 tagacaataa ttttccaaaa ttatgaccta cattgaatac aggcatatat gagttttcaa
    36961 caggtctcgg tttttttgat gagcaaactc cttctacatt aaacttatct ttaaaagatt
    37021 ttatcctatc actaagaatc cctaaattat tgatatgttg aaatacagct tcactttgcc
    37081 ttaaaccttt tgaattatcc cttacttcta acattatttt ttcattgaat ataactttct
    37141 tatctaaaga gatagctgct atagaagtag tatagcagct agtatcaatt ccaattatta
    37201 tattatttcc caatttcatc aacaacactt cccaatatac catttataaa tttaggagac
    37261 ttatcatcac aatatatttt tgcaagttct actgcttcat ttattgatac tttattagga
    37321 gtgtctaaat aaagtatttc acacacagac aatctaagta tagaaacatc tacctttggc
    37381 attctatcta ctgtccagtt tttagcatgc ttatttatta actcatctat tttgtcatga
    37441 ttttctttca atgctttgca tactgtattt atatattttt tgtctataac atcttcaatt
    37501 tcagtatctt ctaactttaa atttgtattt tttgagtatt gaagtgcaag ttctttatat
    37561 ctatttataa tatgttctga attatctttt aaaaaattat ctactttatc ttctaaagtt
    37621 tcaaaatctt ctttattaat atttatttgg tatataagtt tcattatata ttctcttgtt
    37681 gtactctttt gtgccctatc ttttttcatc aatcaaaatt ctcctttaag tttaattatc
    37741 catataaaat caattaccag caaaaaaccc tctgactttt cagagggcta atattaattt
    37801 ttcttagttg cttttgcttc ttctttatca actttatcct tcttaaagct gattccttga
    37861 atgtgtatat ttacttgaga aaccttcagt cctgtcattg tctcaacagt attttttaca
    37921 ttttcttgaa ctttaaaagc tgtatctggt attgacattc catactttat cgtaaccatt
    37981 acatctaaat taacatcctc ttcttcgatt tgtattttta ctccattatt ttttaacaac
    38041 ttatctgtta atgttgctgt agtttctatg ccttcaactt ctaatgctgc taaaccagct
    38101 attgtagcta ttacatcatt agatattttt acttgtccaa atttattatc ttccatatta
    38161 aaacttacct cctgatttta aggaactatt tttataagta taataatacc aaatacaagt
    38221 ctactttgca agaaaataac ctcagttaat tctgaggttt atactttact tattactatt
    38281 attatttgta agtttaatat tttcatactt cacattggct tgttctgcaa ctaaatcaaa
    38341 tatttttgct gcatctttct tttctaattt agcttcattt acaactacat taactttgtt
    38401 atcgcttata taaactaacg cttcttcata tccttttgta ctcaaaaggt tttctatttg
    38461 aagttctttt tcttgaattt taactatatt taatttcata ttagaagctt cttttctaga
    38521 ttcttctgtt gtagatggat tatttatcat ttcatttaaa tcttgaacta actcatttct
    38581 ttgtttttct ctattcattt tcatatctaa aatataagat gcctttttca tatttttctc
    38641 tgatgataat tgagctttta tttccttact tgtctcagtt gccttttctt ttactttact
    38701 agctttgcta tcgactatat caatatcagc actttcctta ccaccttgtt tatctacatt
    38761 actagaatcc tctgtcttac tactataact atcatcagta tttttttgca actgtgcttc
    38821 ttcatatgcc ttaaactctt ttgatgtttc taataaagat ttcttactta gttgataatt
    38881 cactgttcct actaccacta acattgcagt taaagttatt attacaaatc ctcttccctt
    38941 ataattaaac ttcattcatt tatccccccg gttatatgta tttatttaga atatatttct
    39001 acttgatgac cagctacttg taatgatgtt tgtactgcac tataaagtgt ctctttaaca
    39061 cttgggtcac ttgctccact tgctaccact atcactccct ttatctttgg ctctgtagtt
    39121 tttataacta cagggtcact tgaatttgaa gttatcattg ttttattttc actagaagtc
    39181 gtaactgttc tttctccacc ttgtgcatct ttttcctctg ttgtttctgt tgtattattt
    39241 gaattaaaag caggttgtat ttcttcactt gattcaaatg taaccattac atcaacgtct
    39301 cctgcaccat caattttaga tagtattgct gttaattttg actctaaatc atctttttct
    39361 tgttctttag tgacttgctt ttcagcattt ttattagtct ctgtttttcc aacttgttta
    39421 tcgcttttgc tactaggaaa acaagataat aatactaatg aaaccacaca tattcctgct
    39481 atagttatta gtgaatatac ctttctctta tctttgtcat ttaagttttt caacattctc
    39541 ccaactccta tttatcaatt tgtatatctt ctatagaaac atccagcacc tttattaagt
    39601 cgttttttaa tttttcttca tttaggttca acccatactc tgtacctttt ttgaagactt
    39661 gtttagaatt ttctttgtca ttagagttta tgttttcttc ctctctttta gtactattat
    39721 ttttattttc ttcattggaa ctgttattac tttttgcact attattcttt tcttttattt
    39781 ttatattatt tatatttgcc ccattaagct ctatatcttc taaatcataa ccatattcat
    39841 caagttttaa tttaagtact tcttttaacc catcctcata tcccttggat agactattat
    39901 ttccagtctc ttttgccaaa gcatttgtac tatctacata ctgcttgttg tagtttccca
    39961 tagattttaa tattctatct tctaaactca tatcttttga aaaaaatcct actactggag
    40021 ttattacaat aaatacaaac ataaagttta aaactaggtt gacataaggt tttatcttag
    40081 aacttggtaa aatcatatct actatattta ctataaatgc tcctatcaaa acactaacta
    40141 tccatgcctt tatgccctct aacatagcat cctcctctct aaaaacatta gattaaatgt
    40201 aattattttt cactgatata taaattaccc ttgacttacg acacttatcg aggtcaagat
    40261 agctacagtt acaaagaaca ttactgttat agcaattact gatgctagca ttattatcat
    40321 taaatttgcc acttcattta aaaaattaga tattccatcc tctccaacag gctctacaat
    40381 tattgctgct aatttgtaca ctactattac tgataaaatt tttattactg gaagtaagca
    40441 aattccaaca agtaagataa gccctattcc tccaaatata ttttttataa gctgagatga
    40501 agataataaa atatccacag agtcagatac aaatccacct acaacaggaa taaaattacc
    40561 tatagcaaat ttagcagtct ttacactgaa tttatcaaaa ctggttacat acaatccttg
    40621 tatggataca agacctaagt aaacagtaaa catagctcca atagaaacat aatttatttg
    40681 ttttacaaag gagaaaaatc tctttagcct tatatttttt gataaattgt ttattattaa
    40741 aattccaaat gcaacagtaa tagatacaaa tagaaaattt ttaaaaaata catttataaa
    40801 tgttactcct cctatgaaga taggattcaa agtagtcgac gttattggga atccaattaa
    40861 aagtaaaaat gttattaata ttggcattat aacttgcata agacctacag tatggtctat
    40921 tgcatcatag caaatctgta atacatcttt aaaaccaata agtgtaagtg ataccattgt
    40981 gataaatatt atatatgttg ctatttgact tactgcacct gatgaaaaag agttttccag
    41041 actctttaaa atagatgata acagagccag taccaaaatt actgctacta cctttaaact
    41101 tgctttaaat tcatcaaaca tcaatatctt caatccatct ttattgaata aatctaagat
    41161 atttttttct ccactaatta aatcttttac aaatgatttt aaattaacat cattaataac
    41221 tatttcttta tttatatagt cttgaatctc atttatatct agcttgtcta attgaccatc
    41281 tatatactta tctatgctat tttttgtttc accatattct ttatcttcac tacttggtac
    41341 ttcattagca aatatcataa tagcaaagat atttacaaaa aagaaagtaa ataaaaaacc
    41401 tataatcatt ggtaaaaatc tttttttcat aagcaaccat gcctctcttc actctataaa
    41461 cctcaataca acaaaagctc tctaatatac ttatattcat tccaagatac acatctatgg
    41521 aattatattc accaccattt ctacaatgga caaaagtata gggaaagaca ttgacataac
    41581 tattatttta cctccaaatt ctagttttga agcaatgttt ccttccccac aatctttaca
    41641 aagttgtatc gcaaattcca ttaagtatgc tatcccaatt aattttatta ttaatgatat
    41701 atacatagtc gggatgttag ccttgttagc caaatcttgt atactatcta ctataaaatt
    41761 tagcttaaac ataactgaca atagtattat tactccagtt attatagcta tgaaatttgc
    41821 tatctctggt ctatcttttt taattactaa acagagtgta gttgaaatga ttgcaattcc
    41881 tattaattgc attatttcca aattactccc tcctctttag taaagttgaa acattgttct
    41941 tacagtatta aacaagtcac ttatttctgt tattaccata cccaatacga ttattacacc
    42001 tgctaatgta gtaagacctg cccaatcttt tctatctgtt ttttccaata tcatattcaa
    42061 tactgatatt agaataccga cacctgcaac ctttaatatc aatgatattt ccataataaa
    42121 cctccccata ttaaatcaat ataatacata tacctatacc tatgaatgtc actaattttt
    42181 tatacaatac gccttttttg tttatatctt cctttgtctc ataggtttgt tttttcaaat
    42241 tttctataga taaatctatc attctttgtt gtgactctat atcgcttttc cctaaagtaa
    42301 gtattagatt tttcagttcc tcaatttctt tattgcctag ataagtttct ttacttaaga
    42361 catcaatatt ttctgatatt attatttcca aagttttact ttgttcattg tgaagtcctt
    42421 ctgatatttg atagaaaaat ttccaaaaac aaaactcttt atttccacct atcctattaa
    42481 agatttcttc taatgtataa agtccaaaag ataaatccat cctcaaaatt tctaaaactc
    42541 ttattaaatc gtttaattgt ttatgtctac gagtataagt tttgtatatt tgttcaccta
    42601 tcaaataact acttcctatc aagaaagcta taataattat tttaatttgc aaaataccat
    42661 ctcttttctt ctaaatcata aattttttca attgttcctg ctcctctttt tgcagaaaga
    42721 attataacct ttttaaataa ctctttatcc agaagtctat ttaattcttt tctattttgt
    42781 atatcctcta ttgaatctcc atgcacagta gttattaatc ctatacctcc atttaatgct
    42841 gtgtataatg cctttatttc tttttcactt ccaatttcat ctgtcacaat aacatttggt
    42901 gacatagacc ttaaaagcat tgtaataccc aagtcttttg ggcaagtttc tattatatca
    42961 gtccttattc ccacatccat ttgtggaaca cctagataag ctcctgctat ctcattacgc
    43021 tcatctacta aagccacttt taaaccttta aatccataat cttcattacc attacttaaa
    43081 tttcttacta tatctcttat taaagttgtt tttccacatt gaggtggtga tattatcaaa
    43141 gtattattaa tctgattttt tccctttatg atatgactta aaatcttatc cgagcatcca
    43201 ataatttccc ttgataccct tatatttaaa gatgatatat gctttatatt tttgacttgt
    43261 ccatcttcta ctattgcttt tccaactaac cctactctat gacctcctct caaagttatg
    43321 aatccttttt ttatgtcatc cataaatgaa tgtattgaat atttacatat tatttgaaaa
    43381 gtttgctcta catcttctct tgttactaca tatgagtttt gttgatttaa atcaagtgtc
    43441 atagtttttt gattgtaaaa ataatcttta gagtttgcat ttagtatcaa tggtttttgt
    43501 gagcgtaacc taatttcttc tatgttcaga ttattgtttg agactttttc taccttttct
    43561 cttatagttg tagaaagaga gtttattatt tcatcagaaa gtttattcat ctcttgtcct
    43621 cctcctttgt ttatataatt ctatttataa aggacaagga atataaccaa aacatctata
    43681 tttttttaat aatgtttata aataaaaaaa gtgaacccat ttatcttgga ttcacttagt
    43741 aagtataata taaactacta ttattaatct ttataatata tttaataagt attaacaaaa
    43801 agacacttca atcatgaagt gcctctataa catctacatt tcttttatta gccctttctt
    43861 ataagccatt aaaagtagtt ttaaatcttc tatttcctct tgtatcttta ctccttcatc
    43921 agtatctctc accatttttc tctttgcctt atgctctact acaacagttg tcgataagat
    43981 atcactttca tttgcaatgg cttcttcagc agaattaaat ggttcatgcg atactaattg
    44041 caaagttcta gaattgtata tcaaagtgta tccagctata ccagtagttt tttggtaagc
    44101 cctagaaaaa ccaccatcta taacgagaat tttaccatta gcttttattg ggctctctcc
    44161 atttttactc tccacaggaa catgaccatt tattatatga gattcatcaa gttctaaatc
    44221 aaattcttca aataatcttt tacaagccat ctcattttct ctaagtttaa aatatgggtt
    44281 cttattttct ttatgagtct ctttttcagc tataaagtat ctttcaaatg tagtcatatc
    44341 atctttacca aataatgatg aacatttccc agtccataaa taccacataa tatccatgcc
    44401 atacagtttt tcttctgcct tatctttaaa gaaaaatcct tctcttgcta gagactccat
    44461 cttatccata agagccttac ctttatactc ttttcccatt atattcatag acataaagct
    44521 tccatcttca tttaacggta cacatccatg aatcagtaaa tttgagttag cctttaaata
    44581 tatacttcct ttagaaaaca aaaatgaaac atgtttttgt aatttttcac tacctctaaa
    44641 tgaagatact aatttatcaa taacatttct ttcttccata gttaatttat atgggtcttt
    44701 tttgtctatt gtaggtaaat aagtatcttt taatttatat gttttacctt ttaaattaat
    44761 cgtaccttca tcatagttta tcatattaag caagagtcta tgttccattt caaattcagg
    44821 tcttcgtctg ataacctcac cttcaagctt aaattgaatt atacttattg ctttgtgcat
    44881 ttttgccatt aaagactttt ctgttgttgt tacactttgg tcattaacct ttggaataaa
    44941 ttctttacaa gggtcatctt tatacatttc tatagcaaaa gtggctaaag gcaatagatt
    45001 tattccatat atgtcttcta caatgtctaa attcgcatat ctagctgata tcctcagtgc
    45061 atttgctata caagtttttt cacctgaggc tgcacccatc cacaatatat catgatttcc
    45121 ccattgaata tctacacaat gatgttcaat aagcttatcg acaattatat ctggtcttgg
    45181 acctctatca taaatatctc ctattacatg aagtctatct acaaccaatt tttgtataac
    45241 tgtagaaata gcaattataa actccttagc tattcctatg tcaactattg tttcaactat
    45301 acttttataa tactcttctt tatgttcact tttaacatgc tcatgcaaaa gttcttctat
    45361 tatgtattta aaattttctg gtaacagttt tctaacttta gacctagtat atttgctaga
    45421 agcatattta caaagttcta taagtctata aatatttatt ctataaaaat catctatatt
    45481 ttcctcttgc ttaattatta ggtctaactt ttgttcagga taatatacaa gagttgctaa
    45541 catttttttt tcgctgtctc ttattgtatt tgaaaacaat tcttctattt ttctctttat
    45601 tacaccagaa ccatttttta atacatgtac aaatggttca tattcaccat gtacatctgt
    45661 tataaaatgc tctgttccct ttggaagatt taatatagcc tctaaattta ttatttctgt
    45721 acttgctttt gatatacttg gatattgttt tgataataac tttaaatact taagcttgct
    45781 gtttaaataa tcatctgata ttttacacag atttttcata attcgtcctc caaaattata
    45841 ttaagttata ttctttttta attataccat acttaatata cttttttcga gataaaatgt
    45901 acactaatta tattcccaat aaaagtgaca ttcctattaa atcagtataa acaccattat
    45961 aataacattc tttctttagt atgctttcta cttcaaatcc aacttttttg tataatccta
    46021 tagcattata attttcttca ttagtgacaa gagttatctt cttggttatt ccatttgatt
    46081 tacaccattc tataaggtct aacataagcc ttttacccaa tccaattccc caatattttt
    46141 cttttacaac aattcctaat actccaacat gctttccttt tgctttttga ttagaatcaa
    46201 tcgttgcaat cccaactatt tcaccatcta taaatgcaat cagtttaaca gaattatcgg
    46261 atgcttttgc tgattctata gcattttctt gttcctccaa agatatttta tattcatcct
    46321 ttccaaatga cagaaaatga gtttctccac ccacttcatt ataaaaatct ataatgcttt
    46381 gagcatcttc tcttacacct tctctaataa gtacgtctac accatttttt aatgttattg
    46441 ttggcataaa tttacctcct aataagtttt ttgtctataa acataatact attgttcttc
    46501 tattgttaca atatttttca tttattgata acaatataag gctatattaa aataaaaaat
    46561 taataatatt ttaatatagc cttgtagata cttatttgta tttaatttta tgccaatgtc
    46621 taattttaac tcaataaatt gttataacat aattaaacta ttttctttaa attttcatca
    46681 tagacttttc tattataaga cttcattata aagtataatg gtactccaat tgccaaagct
    46741 cctaatccca taattaattg atgcatagat gcttggaata ataaccatgt tccaacacat
    46801 acagcaatta gaggaatcac tgctccaaaa ggagttttaa aagtacctac taattctggt
    46861 cttttctttc taaacactaa tacggataaa gatgttggta tgtattgtat gaatctagca
    46921 actgcactta ttgctgctaa ttcagcaaaa cttccagata gagctattgg tatagtgatt
    46981 agcatagtag ctattatcgc tacatatggt gtaccttttt tatcttttct tgcaaatatt
    47041 ctcggtaaca ttttatcatc agctaaagct acacagcttc ttggatttac aaaagcacca
    47101 cacatacaaa ttccaccaac agaaaccaag gttccaaagg taaccaatcc agctcccata
    47161 tttccaaagc atattcttgc agcatctgcc actggtgtag atgtactaga taacgaatct
    47221 cctagtatac caacacatac aacttgattt aatatatata ttattgatgc aattactatt
    47281 acacttataa ttgctattgg tatatttttt tgtggattct ccatatcttc tgctgcaact
    47341 gctatagatt caaatcctgt aaatgaataa aacattaaaa gtgctgctgc tccaaactct
    47401 gttgctccag ctcctggagg taccattgtt gaagaagtaa aattaactcc ttttataaaa
    47461 aatataccta ttcctataaa tagtattaat ggaattagtt tacctacagt tataacattt
    47521 tgtacaattt ttgatagaga tacacctaat aagtttataa ttgtaagccc aactatcatg
    47581 actacaatta taattttttg tatatgtggt tcacctgctg gagcccatac tgctgataat
    47641 gatgtaggaa aacctactat taaagctccc caagaaatac atcctattac ccatttcata
    47701 agacctactt caaaaccaca aaaatctcca aaagcttctt ttgtatatac ataggcagca
    47761 ccatttttat tgaatttacc tgcaacctca gcaaaacaga atgccataga taaaactaac
    47821 aacatatcaa atatatatac aaatatactt gctacaccaa atgatttcat tgcatctcct
    47881 ggtaatagaa aaactccagc tcctactact gcattaatac ctaaaagtat aatacttatt
    47941 aatcccattt tgttcttttc gttcatgttc aatcccccca aggtatatta taaatttgaa
    48001 caaatattta taaaatattt aaatagtttt tccattttat cacagtaatc taccatcatt
    48061 tctggatgcc actgtactcc tactacaaaa ttttcatcct ctttctcaat agcttctatt
    48121 ataccatctt ttgagtatgc tatggctttt aatccttttc caagctgatt gacactttga
    48181 tgatgataac tatttgtaag taattgtttt cctaaaattc cctctaaaat acttccttct
    48241 ttaacatcaa ctttatgagt agctacatgt cttttagaag attgtgtatg ttttatataa
    48301 cttccttcta taagattatt atcttgatat aaagttcctc ctaaacttac atttaaaatt
    48361 tgtagtcccc tacatacacc taatataggc tttttaagtt ctaatgctat acttattgca
    48421 attaaatcaa attcatccac ttctggatat ataaatgtcg tttcttctct tgtttcttct
    48481 ccatacagtt gaggattgat atcccatccc ccagatatta agactccatc aaccatttca
    48541 atctgttttt ttataacttc tttatctgta tttacaggaa ttattactgg actacctcct
    48601 ccttttagca ctgcatttat ataatcatta tttacatatg acctttcaag acctggaaac
    48661 ataccatttt ccattattat taaatttcct aaaatcccta ttattggttt cataattaaa
    48721 ctcctaacta atcgattgtt ttatgtatta ctttatattc atataatttt ccaatgctag
    48781 agacagttgg tctgggcaag atgttggctt tgttttacac tctattcctt ttaacttttg
    48841 tattacatct tctatattca tgccttcaac taatactttt agccctttta aatttccatc
    48901 acatccacct ataaagttta catttgtaac tttattttct tttacttcaa attcaatttc
    48961 tgtagcacaa gtccctgttg ttttgtattt catcattaaa cctcccaatt attttgtcgt
    49021 cttatctcta taattagcaa tatgtatgcc aaaatctata attattttta tttattattt
    49081 atctagtatt ttcaatagtt ttattagttg tattttttac ttctaattct atgtacactt
    49141 ttcttacaaa taaaaatagg taatgggtta ttctaactta acctattacc tatctaatcc
    49201 tattttaaaa acctattaat atttaattat aaattacaat attctttctg acataatata
    49261 aattaatctc tataaatata aaagtttatt attatttaaa tatctaaatt caaaatatgt
    49321 gatttcaata tcaaatactt agcttaattt atattattat aaagttttat cccctctgag
    49381 gttatttgac ttcctcctct accagattta gatgatatgt atccacattc acttaaataa
    49441 gatagcacct ttctaacttt gctttcagaa atctcaatac cttcctgtat aagcttttcg
    49501 attataaacc ctcttccaat tccagaggat gactctcttc tttcatatag aatcctcagt
    49561 atttcctcaa attcttttct tgtataacca aatccatctt cataattgtt agcacattct
    49621 acccttatat atggtggtaa gtcatctcta aaaaccatac tatcacacat tagacttaca
    49681 taagaagcaa cattttgtaa ctctcttata tttcctggcc aattatattt ttctaaaata
    49741 gttataactt ctggcgaaag tcttatattg tttttcaaaa agaaattcat aagtgttatt
    49801 atatcttctt ttctattcct caatgatggt acatctattg gcaatacatt tagtctataa
    49861 tacaggtcct ctctaaattt tccttctcta atcatcttta gtaagttttt gtttgttgct
    49921 gctatgaccc taacatctat gtttataaca ttatgggaac ctataggcat aacctgcttt
    49981 tcttgtaata cccttagtaa ctttgtctgt agcaatggag gcatatctcc aatttcatcc
    50041 agaaatatag ttccattatt agcaagttca aatagaccct tttttccttc tcttaaagct
    50101 cctgtaaaag agcctttttc atatccaaac agttgacttt ctaatagact atctggaact
    50161 gctgcacaat taactgctat aaacggttga ttacttctat tggaagcatt atgaattgat
    50221 tgtgataata attctttacc agtaccactt tctcctatta ttaatacaga aagttctgat
    50281 ttagatattt ttttagccaa ttctacacac tttaccatat ttttattttt agtttttata
    50341 tctttaaatg tatatcttgc tatctgacct tgttctctta atttattagt aagattttgt
    50401 tctaattttt ttatatacgt tatttcttgt aagttataat atatcccagc tttattcccc
    50461 atagaaaaaa tacttttttt atttacattt atatattttt tatttgtaaa taccacttca
    50521 tcaattattt ctttgtcttc aagtaaaata tttaaatctt cagaaatgat atcttctatg
    50581 tttttgcctt gtggattttc atttatacct aaaattttta aagcttcttt attaaatgtg
    50641 tttattatac catctgctga agtaaatatt attccatctt ttgatagatt caatataaca
    50701 tcttgttctt ctatttttaa aaacagttgc ctataattat ctttaactcc attatctaaa
    50761 cttattaaac tctcagaata tgccattaaa tttttacgta tttctttaac atctattcta
    50821 agaccattta ttatttctat aaaggtagat atatcaatat atctatttcc aaggtcgatt
    50881 actttattta tataacttgg tacttttccc tttactccag gcgttatagc tatgtctata
    50941 tttttataaa tttttccttc aatatatgga gtaaacttta aattttttac tcctattttg
    51001 taaaataagc ttatcgtttc taaggtagtt tcttttgtat catttacaac caatacttca
    51061 gttccatttg gtattgaaaa taatccatat atttcatttt ctttaagtgt tctccttatc
    51121 actataatct tactatcttg tactaaatgc tttctcatac tgtttaatct atcatcattc
    51181 attactagta caaaatcacc ttgtatttta tcattctctt ttaaaacttc cagataatag
    51241 tggtttatat caatataatt acctaaaacc aaacgtatat tttcttctaa gaaagatgat
    51301 agtttagtta ttttatcagt tactatagct attgattgtt tcatatttat acctcttatt
    51361 tatatagtat ataattactt atatactact ttatttctac caagttgttt tgctttatat
    51421 aaatttttat cagcttcttc tagtacatct ttgctatctg aaacatgagc tacacctgca
    51481 cttatagtca cagtcacatc atcattccac tttttatttg caattgcaac ccttatactg
    51541 tcaattatat ctgctacttc atcaccagat ttatttctta ttaatacaga aaattcttct
    51601 cctccgtacc taaagacttt atcatcttgt tctaacataa cacaaatggt atttgttatt
    51661 ccctttataa cagtgtcacc aaatttatgt ccataattat catttatgag cttgaaatta
    51721 tcaatatcta tcatcacaag tgcaaaatta tcatctttct ctctgtactt ttcatacata
    51781 atatcaaaac tttttctatt ataaacattt gtaagaccat catgtaaatt ttgtgcttta
    51841 aaatacttca atcggttgta taaaaaagta gaccctaata tagcaattaa aattactgta
    51901 aataatattt tataatattt tatttctttt ttagtttttt caaatagctt actttcgttt
    51961 gatactttat caattatata gaaactagtc tctgaatctc ttatactttt gttctcttta
    52021 tattcattta ttaacatctt ttgatactca tttaaagatt ctatatttcc ttgtttttca
    52081 tatatattta atatcttatt taaatttttt attttctcct gggttaactt tcttttagta
    52141 gatatctcta aacttttttt ataattatct attgcagaat tataattttc gcttttatat
    52201 tctaagtttc ccattgccat ataatagtac atatctttat ctaatatata aactgttcta
    52261 tctgatttta taagataatc agctttttct aaaaaagtct ttgccttttg tatattattt
    52321 ttgcccacat acgcatttga ctgcattata gaggccatta tatcaaaatc attgtaatta
    52381 tccgtattta caaacttttt ataatctttt atcctgctac ttatttcaat agctttatca
    52441 tattcgccct cttctacata tatttctgct agatttataa tagcatataa tctaaccatt
    52501 ccattttttt caccttcatc aatatctatt ttaaaagaat cctttattaa tttctctcct
    52561 gtttcatagc cacctatctt taaaaatatg ctcgccaaat caacatctag tcttgctttt
    52621 tcataattat tccccaattt ctcagccaac tttatagact ttacagttaa atctactgcc
    52681 ttagaataat tattatccat tatatacact gatgctaatc ttttttctat attaaatcta
    52741 cattcatcag ataatttcac atctgattct ctcatctttt ctaaagaatc aatgactatc
    52801 ttcgttccat ctggaacata tgaaatagtc tttaacatat cccaaacttc attatatact
    52861 ttattgtatt ttttttctgg aatagattcg aaagaagtct taaccacttt ttttgcttca
    52921 tcatactcct tatctgccac aaggctttca gacatatatt ttcccttatt tataatttct
    52981 ctttctttca atccattttg gtcatgcttt ataaacaaaa taatactaat aagtattata
    53041 catataaaaa ttatcttttt gggtaacctt ttctttggta gtctaaaatt caaaatttta
    53101 gtcctccttt tgtatattgt agaatgaaaa cttacatata taaataacct cttaataatt
    53161 aataatacaa tatatcaaaa tgatttacaa catatgctag acttaaatct taataaaaaa
    53221 gtctcctaaa ataatttagg agactttaaa tttaagctaa tataaattta tacagttaaa
    53281 acaagtgctt gttttttagt tttatattta atatttattt atacatattt ttttagtact
    53341 attgtagcat tatgcccacc aaatcctaaa gaatttgata gtgcatatct aatatttttt
    53401 tctttacctt gatttggaac ataatctaaa tccaaatctt caccaacttc ttgtatgttt
    53461 atagttggag gcacaaaact atcttctata ctcatagcac aaacaacagc ctctatagca
    53521 cctgatgctc ctaataagtg accagtcata gattttgttg atgacacaca taagtcatat
    53581 gccttttctc caaatacagt ttttatagcc atagtttcat ataaatcatt gtaataagtt
    53641 gaagttccat gagcatttat ataatctact tcttctaatg gaacatttcc atctttcaaa
    53701 gccatattca tagacctagc tgctccctct ccattttcag ctggagttgt catatggtat
    53761 gcatcagcag ttaaaccata tccaactact tctgcatata ttttagcgcc tcttgctaaa
    53821 gcatgttcta agtcttctaa gataacaata cctgctcctt ctcccattac aaaaccatct
    53881 ctgtctttat caaatggtct tgatgcagtt ttagggtcat catttctagt tgacatagcc
    53941 ttcatgttac agaatccagc aaaagcaaga cctgttacag cagcttcaga accccctgct
    54001 accatgatgt ctgcatcacc tctttgaatt accttaaaag catcacctat tgaatgagtt
    54061 cctgatgcac aagctgtaca tacattagtg ttaggccctt ttgctcctaa aaatattgaa
    54121 acttgaccag ctgccatatt tcctatcatc ataggtacaa aaagtgaact tactctttta
    54181 tttccttttt ccaaaagaat tttatgttga gtttctatag cttcaactcc acctattcca
    54241 gaacctatta taacaccaaa acgttctcta tcaactttat ctaaatcaag atttgcatct
    54301 tcaactgcta atttagcaga tactattgca aattgagcaa atttatctaa tctcttcaat
    54361 tcttttttac ttatatattc ttctggatga aaattcttaa cttctcctgc tatctgagtt
    54421 tgatatgtgc tagcatcaaa attagttatt ttatctatac cagatactcc agattttata
    54481 ttactccaga actcttcttt tcctgttccc aacggcgtaa cacatccaag tcctgttatt
    54541 actactcttt tattcatcgg atacctccac ttttttaaag ctcgactatt tattagcttc
    54601 tatatactta actatatctc ctatagattt gaagttttct gcttctgtat ctggtatttc
    54661 tataccaaat tcatcttcaa gtgccattat tatttctact gcatctaatg aatctgcttc
    54721 taaatccttc attaatgatg tttccatagt tatttcttta tcttctactc ctaattgctc
    54781 tattattatt tctacaactt tattaaacat tgtgtacctc ctaaaatttt ttattttaat
    54841 agatttctct actttttaaa ttattattgc attaccattc caccatctac atttattact
    54901 tgtcctgtta tataacttga catgtcacta actaaaaatg ctacggcatt ggctacatct
    54961 tctggtttac cataagattt ctttggtatg tttgctagtg ttgattcttt tacatcatca
    55021 cttagtactt tagtcatatc tgtttctata aatccaggtg ctactgcatt tatatttatg
    55081 tttcttgatg ctaactctct tgcagaagct tttgtaaatc caattacacc tgcttttgat
    55141 gcacaataat tagtttgccc tgcattaccc ataattccaa ctactgaagt catatttatt
    55201 attcttccat acttcttttt catcataggt ttagtaactg cttttgtaca attaaagaca
    55261 ccttttaagt ttatatctat aactctatca aaatcttctt ctttcattct cataagcaga
    55321 ccatctttag ttatgcctgc attattaacc aatatatcaa tttttccaaa ttcgcttaca
    55381 acagaatcta tcatttgatt cacttcatca aatttagaca catcacattt tatagaggta
    55441 cactttaccc ccatactttc tatttcattt ttagttttta gtgcttcatc ttctttagaa
    55501 gtataattga ttactacatc agctccaaaa gatgctagtt tttttgctat ttcttttcct
    55561 atacccctag agccaccagt aacaactgct acttgtcctg taagatttat cattatatct
    55621 ctccatttct ataattttgt acaaattcat taagagaatc tataccatct atattataaa
    55681 tattgacatt tgctttttta ttggaagcta ttttcttaat aaatgctttt aaagtttttc
    55741 caggtcccat ttctataaaa gtatcatatc catcatttaa aagtctttct atagaatctt
    55801 cccaaagaac agatgaactt acttgtttta taagcaggtc tttaccttcg tttttatagt
    55861 aatctgcatt tacatttgcc accacatcaa ctttaggttt agttatgtta actttttcta
    55921 attcactggc caattttaca ccagcttctc ttagcattga tgagtgaaaa ggtccactta
    55981 catttaattt aacagctctt tttgctcctg cttctttgca tttcaccatt gcttcttcta
    56041 tcttttcatt ttcaccagat ataactattt gaccaggaga attataattt gctacttcca
    56101 caatacctcc ttgtatatct ttaactacat tttctaatat acttctatct agacctaaaa
    56161 ttgctgccat agctccaaca cctgttggaa ctgtatcctg cataaactta cctctttttt
    56221 tgaccaagca tacagcatct ttaaagtcaa ttgcatctgc tgcaaccaat gcactatact
    56281 ctcctaaaga taaacctaaa catgcactat attttaaatc tacttgggct tgtactgctt
    56341 ttaatacagc tacactatgt gtaaccatag caggttgagt gttttcagtt ttagaaagtt
    56401 cttcttcatt tccattaaac ataaggtttt ttaaatccat atttaaggca tcactagcct
    56461 catctattac acttttagca acagtattat tttcatataa atccttggcc atacctacat
    56521 attgagctcc ttgaccaggg aatactagtg caacttttcc catcttgctc ctcctgattt
    56581 acagttctat tgctggcata atctctcttg cttgatttac catagcctct ataatttcct
    56641 tacaaggtgt tatttctttt accatagcag cactttgacc tgccataaat gaaccttttt
    56701 ctatgtctcc atctactgtt gcaaatctta aagctcctgt acctttttta tccagttctt
    56761 caggagtagc tccattttgt tccatcttta aaaattcttt tgatagttta ttttttaatg
    56821 ttcttactgg atgaccagta cttcttcctg ttacaattgc atctctatct tttgctttta
    56881 gtactaagtt tttatagttt gaatggacag aacactcttc actgcaaata aatctagttc
    56941 ctacttgaac tgcactggca cctaatgcaa atgatgctgc aattcctcta ccatctacaa
    57001 ttcctccagc agctattaca ggtatgttta cagcatcagc aacttgtgga actaagacca
    57061 tagtagtaag ttctcctata tgtcctccac cttcagtacc ttctgctatt actgctgtag
    57121 ctcctagctt ttccattctt tgtgccaaag ctattgtagg tactacagga ataacctttg
    57181 ttccagcttc ctttaatcta tccatatact ttgcaggatt tccagcacca gtagtaataa
    57241 cttgaacttt ttcttctata atcaaatcaa ttatatcatc aacaaatggc gacataagca
    57301 ttacatttac tccaaaaggt ttatctgtta attttttaca ctcaacaatt tctttcttta
    57361 tagcttcttt tggtgcgttt cctgctgcta ttatgccaag tcctcctgca ttagatacag
    57421 cacttgctaa tgatgcagta gctacccatg ccattccccc ttggataact gggtatttta
    57481 tatttaatat tttgcaaatt ttattcatac aattctcctt cacttgaaat cataaaagta
    57541 aactttttat tattaatcaa ctttattttg tgtataagtt taattttgtt aattaaatca
    57601 ttttagatat tttatactat aaagtccact tgacaactga agccccccaa gttagacctc
    57661 caccaaagcc aactaaaact acattatcac cctttttaat tttaccttct ctataagctt
    57721 catctaatgc tactggtata gatgcagcag acatatttcc atatttgtct atatttacat
    57781 aaactttttt catatcaagc tctaatctct tagaagaagc ttgtatgatt cttatattag
    57841 cttgatgtgg cactaagtag tctatatcag ttgtatttag atttgctttt tcaagagctc
    57901 ttaaagaagt ttctgccatc tttctaactg caaatttaaa cacatcacta cctgccattt
    57961 ctattgtatg tagattagct tctacagtct ctttacttgc cttaagtctt gaacctccag
    58021 caggtacttt taaacaatct tttcctttac catcagagcc catatgtgta gacagtattc
    58081 caccctcatt tacagggcca ataacagctg ctccagctcc atctccaaac aatactgctg
    58141 ttgttctatc atcataattt aaaaacttag aacaagtttc tgctcctatt acaagcacat
    58201 ttttatagca acctgtttcc acaaattgct ttgcaatagt tactccatat acaaatccag
    58261 aacaagctgc tgatatatca aatgcagtag catttactgc tcctattgca tcttgtacta
    58321 tacatgcagt tgaaggcaaa gacatatcag gagtaattgt agctaatata atcagctcta
    58381 tatcctctac gtttaacttt gcacattcta tagcttttaa ggcagcttta gatgctaagt
    58441 cagaagttgc ttcagactct ttggcaaatc ttctttcctt aataccagtt ctagtactta
    58501 tccactcatc tgatgtatcc attatttttt cgaagtgaaa attatcatat gattgctcag
    58561 gtagataact tcctactcct aatattccag cctttgtatt cattatatat taaacctcca
    58621 aaacgagttt attcatcttc gttattttta ttttcttcat tgtatttgct tataaattgg
    58681 ttaatatctt caacgacttt tccctttgaa aattttattc cttgatttat agcatttttt
    58741 atagctttag catcagaact accatgagct tttataactc ctccatttag acctaaaagt
    58801 ggagctcccc catactcaga ataatctata aaacttttta attttcttaa atcatccttt
    58861 ataagtaatg ctcctatttt actttttgta ctggccataa aagtttcctt tataagactc
    58921 ataactgaaa gtgctacacc ttcagcagat ttaagtaata tattacctgt aaatccatca
    58981 catatgatta tatctgtgta tgcatttata acttctctag cttctacatt ccctataaaa
    59041 tttaaatcta attttttaat ttcttcatat gaccttttga ctaaatcatt gcctttgcct
    59101 tcttctagtc caacatttgc taatgctacc ttaggatttt caagacctaa aacttttctt
    59161 gaataaatat tactcatagc tgcaaattca actagattct taggtttaca atctgcattt
    59221 gcgccacagt ctgctataag tgtcattcct cgctttacat ttggtattgc tgaacataag
    59281 caaggtctat cgattccttt tattctacca acaacaaata atccaccagc aagtaaggct
    59341 cctgtatttc cagctgatat tatagcatct gcctttcctt cttttacaag atttaatgct
    59401 actaccatag atgaatcttt tttacttctt atagccttta ctggtttatc ttcgttttct
    59461 ataatctcag tagtatgaac tatctctaat ttatttctat caaattcata atttgaaaat
    59521 tccttttcaa gtaaatcttt atctcctgtg attattaaat caacctgata ttcttttata
    59581 gcatttactg cgccttctac attagattta ggtgcattat ctccacccat tccatcaatt
    59641 actattttca taatttccct cctaatctaa ttcttcaaag ataaactttc ctctaaatat
    59701 ttgctcttgg gctttattgt tgataacaac ttttacataa tgctttttat ctatatttct
    59761 atacacttct gcttttgcta taagtctatc ttgttgttct atcaacttaa aactttttac
    59821 atttgcaact ctcataataa ccttaggtgc atctattata gccattgcca atgaatctgc
    59881 tagagaaaaa atatacgtat cttttaaagt attagtctta gagtaaatca tgtcctgtgt
    59941 aacttctaac atagatatac ctaatcgccc tacagataaa tcaatgattt ctcctgtaat
    60001 ttcctttact cctaaagtct ttacttttga actctgagtt tctgctattg atttgactct
    60061 ttctcttagc tctggtatgt ttagactcat tctatctaat cttatggtct gtatacttac
    60121 atcaaacaga cttgataatt cttcatcagt ataaaaagga tctgtcttta gcatatctat
    60181 aagctctttt tgtctttggg ctttactttt ctttttcatg ttccctccaa attttatagc
    60241 tgtaattagt accagctact aatagtagta tatagtaaca cacaaaaatt ttcaatactt
    60301 atattattat ttttctattt tttaatatgc ataaaatcca cttattttct ctagtaaatc
    60361 atcttatttt tttatatgta caaaaaaaac atgtagagta tactctacat gctttttaga
    60421 agctattact tagacacaac ttctttacct ttataatatc cacagtctgg acacactcta
    60481 tgtggtaatt ttggctcatg acattgtggg caacttacaa atcctgttgc ttccatcttt
    60541 gagttagctg ctcttctcat ttttgtgttt gatttagacg ttttacgctt tggtactgcc
    60601 atttacgcca cctccttagt caaaatttaa ttaaataaat cttttaattt agcaaaacga
    60661 ggatctatgt attcctcatc gtttgtaatt tcactgcaag aacactcttc ttcatttaag
    60721 tttgccccgc atacttgaca aagaccttta cagttttcac tacaaagaac tttatgaggt
    60781 acattaaaat ctaatgtctg ttctattata tcaataaggt cgatttcttc accatcgaat
    60841 ataaaaggat caaattcctc aaactcatct tcatcataat cttcttcttt tactaaaaaa
    60901 ccttgtatag aatactctag tggtatttct acttctttaa gacatcttga acaattgtca
    60961 acaattgtaa aattgacatc tatatctaga tacaaacctt tattagtctt tgacactttc
    61021 ccttttaaat ttacaggtga tactaatttg taaatctcat cacaataact aatagtatca
    61081 attttttcac aaaaattcaa gtctattttg tcagtttctt ttctatttat tttttctatg
    61141 ctaactttca ttaagttcac ctcaacatat caccaaattt attatacaaa tctagcattt
    61201 gtttgtcaag tatttttact tgataggcat aggtttaatt taattatttt accaatctta
    61261 atgtatctct agctatcatt aattcttcat tagttggtat taaaagcatt tttactttag
    61321 aatcagcagt agatattact gtttcttttc ctctaacatc attagcttct ttatctaatt
    61381 tcattcctaa aaactccatg ttagaagcaa tatctgctct tatagccttt ccattttcac
    61441 caacgcctgc agtaaatact acaacatcca atccattcat ttcagcagca taagcgccta
    61501 tatatttttg tactttttta acatacgctt ctaatgtagc ttgagctctt tcgtctccat
    61561 ttttagctgc atcttctata tctctgaagt cactagaaat tccagtcatt ccatatactc
    61621 cagattcttt attcattaat ttatccaatc catcagcatc taaaccttct tttctcatta
    61681 agaatggtaa tatagctggg tctatatctc cacatctagt tcccattatt aatccttcta
    61741 atggagtgaa tcccatagat gtatctacac attttccacc atcaacagca gctatagaag
    61801 caccatttcc taagtgacaa gttactattt ttaaatcttt tatatctttt cctaatatct
    61861 ctgctgctct ctgagataca taattatgag aagttccgtg gaatccatat cttcttaccc
    61921 catatttagt atatagctca tgaggtaaac catataagta tgaagattta ggcattgttt
    61981 gatggaaagc agtatcaaat acacctacca ttggtacatc tggaagtata gctttacaag
    62041 catctattcc cattatgttt gctggattat gaagtggagc taaatctata cattctttta
    62101 aagcttcttc tacttctgga gttattacta ctgaagttgc aaatttttct ccagcatgta
    62161 caactctatg tcctactgca tctatttctt tcatttcttt aactgcacca aattctggat
    62221 gagcaacagc ttctaaaact aatgctattg catctttgtg gtccttcatt ggttgttcaa
    62281 caacgtattt atcatctcta cctgcttttt catgttttaa tatagaacct tctattccta
    62341 ttctttcaac caatcctata cataaaactt cttcattatt catatctatt aattgatatt
    62401 ttaatgaaga actcccacag tttaatacta atattttcat tattatttcc tccttagatt
    62461 tttttataaa taatatgtaa taaattttga tttgtaataa atgtctaaat aaaactctat
    62521 cttttattat tttgttatag atatattatt gtatacatta aacgattttc ataaataata
    62581 tatcaccttt taatataaaa gtatatactt tttttttata ttatatcata tttctagtat
    62641 ggtaaattgt gtatttcact aataatatat taacaagtta acttaatgta gattattctt
    62701 tcccatttgt tataataata taatataaag agctaataaa gttattttaa taacatttaa
    62761 ccagtttttt atgtaggtaa catttctaca tttttataaa tttttttacg ttttttaatt
    62821 ttataattaa aaatttaaat tttatacata ttataataaa ttgtgatata tataaaataa
    62881 ttaaagataa aaggagtatt ttatgaacat acttggatta atagttgaat ataacccatt
    62941 tcataatgga cacatatatc atttatctaa atctatagaa aaaacaaatg caacacatac
    63001 tgtagcaata atgagtggaa attttctaca aagaggcgaa ccagctttat ttgataaata
    63061 cactagagca aaaattgctg tcgaaaatgg tgtagactta gttatagaat taccaacttt
    63121 atttgcttgt caaagtgctg aaattttttc tcatggtgct ataacaattt taaattcact
    63181 aaactgcata aattctatat gttttggtag tgaagaagga aatacagaaa ttctttataa
    63241 tatagctgaa attttagcaa atgaaccaaa tgaatttaag ttacttttaa aaaaatattt
    63301 agatgatggt ctgttatttc caacagctag agctaatgca ctttttgatt atatacatca
    63361 agacaaaaaa aataatttta tacaaaatta ttcaaaggaa caattatcaa aaacattaaa
    63421 ttcatcaaac aacatactgg gtatagaata cataaaaaac ctcatccatt taaacagtag
    63481 tataaaacca tttactatct ccagggtcca atcagagtat aattccgaag aaattgagag
    63541 tgatatttgt tctgctactg ctataagaac ttcacttaaa gaaaatacag acctttttca
    63601 tttaaaaaat gttattccag aaaaaactta taacatccta aatgaaaaaa tagataatgg
    63661 ttttttacct atgtttgatg acttcttctt tgatatttta aaaacaatta tacttagaga
    63721 tatggacact ttaaaagagt attttgaagt aaatgaaggc atagaaaaca gaatctataa
    63781 agatatcttt acatctgaat ttctacatga actacaatta gcaattaaat ccaagcgata
    63841 cactttaacc aaaatcaaac gaactctaaa caatatattg ttaggtatta aaaaaagcga
    63901 catgcaactt ataaaaaaca tagatactat accttatata agaatacttg cttttaatga
    63961 taaaggtaga gaaattctaa aagagataaa aaataaatct gaaataaaaa taataaacaa
    64021 gttttcaaat atatcatttt cattagatga tacgattttt aaaacactca taagttatga
    64081 tataaaagct acaaatatat ataattcaat atattataaa aacaataaag atttagtaaa
    64141 aggccctatg gatttttata ctcatccaat atatgtaaag tagtttttta aaataactat
    64201 atttataaaa atcattttat taactcttta ttatataaga tacaatagtc ttactttatt
    64261 tatgtacaca tgcttttagg atgacaacat caacttaaat attatgttac tttctaaatt
    64321 taagtaaata ttgccatcct aaaaatttta caatttagct tcagatttaa aagtaaagtt
    64381 taaaatatta tatttaaatc taatttaata ttttttgttt tgtaaatatt attaaattaa
    64441 tatttctaat atattttccc tggatttaaa atatttttag ggtcaaaagc taactttata
    64501 tttttaatta acatcatata agcatctgaa tttgattcat gtaagtactc ttttttagca
    64561 tatcctatgc catgttcacc agaaacttga ccactaagtt ctctagattt tttatacata
    64621 tagtcaaaag tttcttttaa tcttattttc catgtattat catccatacc atcttttaaa
    64681 atatatatgt gtagatttcc atctcctgca tgaccaaaac tttttattct tatttttaat
    64741 ttgtcttgaa gctcgtgagt gtatcttata aactctgcta tcttatctct tggaacaacg
    64801 acatcacatt catccatttg tgtcgtagat gcctttatag cttctaaaaa tgcacctctg
    64861 gctgaccata tagaatcgtt tctttcttgt gtatctgata taaatacatc taatgcacca
    64921 ttttctaaac ataaattagc tactttttca tattcttttt ctatatcttc agtgctattt
    64981 ccatcaaatg taagcaaaag ataagcatct gatgtattat ctggaaactt tttacctaaa
    65041 aattcttctg ctgccaatat cacatctctt tccataaatt ctatagccgt tggtattgat
    65101 tttgatttta ttattttagg aacagtttct attgccattg ataaatctgg aaatggtata
    65161 agcaaactta tacttttctt tggtaaagga agcaatttta atatagcttt agtaactatt
    65221 cctaaagtac cttctgagcc cactaataaa tcctttatac tatatccaga actattttta
    65281 accacctttc cacctacatt tataatttct ccatttggta gtacaacttc aagacctctt
    65341 acataatccc ttgtaacgcc atattttact gctctcatac cacctgcatt agtgtttata
    65401 ttacctgcaa ttgtagcact tttttcacct gggtcaggtg ggtaaaataa atctctatct
    65461 tgaacatatt gacctattgt catcaataaa acacctggtt ctactgtcaa tgttaaattt
    65521 tcataatcaa cttcaagtat tttattcatt ttacatagat taatcattat tccaccattt
    65581 atggcaacag cagcacctac aagaccagta ccttgacctc ttggtgtgac tggtatatta
    65641 tttttatatg cgtatttcat tattttagat acttgttcag tttcaagtac atttactaaa
    65701 acttcagggt acttctcaat ccctccaagt tcatcatgtg aaaaatcttc atttatatca
    65761 cttccaacta atacattttc ttctccacaa gtatctatta aaaaatctat atctttttta
    65821 tcgattaatt tatacatttc tatcccccta tttagctgct gatgccatat atttttgatt
    65881 attatctttg ttattttcta ttttttcaat caatttagga ataatatcat aaatatcacc
    65941 tattaaagct aaatgtgcta catcaagtat aggcgcttta tcatctttat ttattgctac
    66001 tatatagtca gcaccctgca tccctgcaac aaattgaaca gctccagata caccacaagt
    66061 tattatcaat ttaggtttta cagttctacc actaagacct atttgttttt tagcatctat
    66121 ccaacctgct tctattacag gtcttgttcc tgccacttga gcgtttaact tatcagctaa
    66181 tttatatatc atctccatat cttcttgttt ttttattgct ctacttgcca caactatcac
    66241 ttcagcttct tccagaccaa cttctttatt tttttctttt acactcagta ccttaatttt
    66301 agattttagt tctttttttt ctactttaca taaagttatc tttcctgtag tattctctat
    66361 tttttctggt gctgaaaata ttttatatct tacagtggca aattgtggtc tattattagg
    66421 tgtgtttata tgagccatta tatttccacc aaatgctggt cttatttggt ctaaatcagt
    66481 atttgattga atatcaagta ttgtacaatc tgctgtaaga cctgttctaa atctagcggc
    66541 aagtcttgga gctaatgacc tacctaatgt agttccacca actaatacta tcgttggttt
    66601 tattttatct ataaagtttt ctattgcttt tgaatatggt tctatcctaa aatctttaaa
    66661 ttcatcttca tcatatacaa atacttcatc caccccataa gaaatcaaat tactgcactt
    66721 atcttttatg tcttttccta caaatacaca atacacaggt tgttttattt ttgatgccat
    66781 ctcacgagct ttacctataa gctcgtacgt tacaggatgt atatttccat tatgatgttc
    66841 aacatatact gcaattcccc tccattcatc tttattaatt tgtactttac tactctctat
    66901 aaattcaaat gcgccttttg gtccactttt gacacacaac ttgcacatct tacagccagc
    66961 acttatttct actatacctg acttttcttc tatagcccca aaaggacata tttctaaaat
    67021 tctctttaag tcagttattt tatcttgatt tacaactatc tttgacattt attactcccc
    67081 cttacaccaa ctttaattcc tctaatttat ttacaagtgc aaaacttagt tcatctgcat
    67141 ttcctcttac aatattttta tctgtatttg gctttggagg aaatattctt acaacttgag
    67201 taggagaacc attaagtcca tagttatttt catttttatc ttcaaagtca tctaagctat
    67261 atacaggtat ttctctatct ttagtattaa gttttaattt aaatgaaggt agtcttggtt
    67321 gaaaaatgtc tttttctaca gttattaaac atggatattc aatctcacat acttgtaaat
    67381 catttggcat atctatttca acaactatac tttcatcttt aacttcaatt aattttgtaa
    67441 cgttagtaac atgaggtata tctaaaaatt cagctacttc aggtcccacc tgtgctgtat
    67501 caccatcagt agtttgtttt ccacaaatta ttaggtctac ctttcccatc ttcttaatac
    67561 cttgtgatat ggtataggaa gtagccaata catctgctcc tccaaatctc ctatcactta
    67621 ttaatgctcc ttcatcagct cccatcataa aactttcttc aattaccttc tttgcctgag
    67681 gaggacccat gctaagtact tttagattcg ctttcttatc ttcctttatt ctaagagctg
    67741 tttctaaagc atataggtca tagggattca tttttgaatc tactccatct ctttttagta
    67801 ctcctgtagt ttcatcaact tctactgaag tcgttccagg aacttgttta atacatgtca
    67861 aaatttccat aaagtacact ccttttttat ttaactataa ctgatactcc atcaggtata
    67921 actactactt tgctctcctt accaactata ctattcgcca tttctaaagc ttctttaaag
    67981 ttaaatgcat gtttcatatg catttttttt atcatttcag gattacactt atctgttacc
    68041 attatcacag tatatttaga taatattctc gctagtatct gaaattccca ttggtctgga
    68101 atcgtatcta ctctatcgac acttctaatt ttatctaaaa gttgttttgg agaatctgca
    68161 tttgctacat tttcataaaa agattgacct ccatgaccat cattacatgc tgaaatcatt
    68221 attattactc caccgtcttt acaagtagct tcagctgctg tcattccttt aacagattga
    68281 taaatatttt ggtctagtgg atatccacca tttgtagtta caacaatatc agattttata
    68341 gaatttactt ttgataactc tgttacaaat ctacatcctt tagtatgtgc tttttcgaca
    68401 tcaccagcaa aggaagcaat tattttttta tctttatcta ttacaacatt caatatgaat
    68461 gctaattttg caactttagc tgcatatacc atatcctcat gaataggatt attattcaat
    68521 tttccagttc ttgaattatc actatctata aagtcactac agtgattgta cattatagtc
    68581 tttgcagatg cgattcctgg aagtacgctt tttctgccac ctgaaaaacc tgcaaagaaa
    68641 tgaggttcta taaaaccttc tgctatcaaa agttctgcct catatgctag tttgtttata
    68701 tataaatctc cacctgaagg caatatccct actttacaca tagatttatc atcagtagat
    68761 atatgcataa ctatatcttc attatctact atttcttctc ccattttata aattagctct
    68821 tcccttgtac ttggcctatg aaatccagtt gccactataa tcttcacatc aatttctgga
    68881 ttaacattcc taatccttct taatataatt ggcatagtta ttctacttgg tacaggtctt
    68941 gtatggtcac ttgtaattat gactacattc tttttcccct taaccagttc ttccagagaa
    69001 ttagagccta taggattatt catagattct tcaactatct cttcttgagt cttatgttct
    69061 atataattat ccgattttga ctccaaaaca ccgagaaaac gttcatcagg tatttctaaa
    69121 atcattcctt gttttgaata cggtactttt aactttacca tttttaatct cccattataa
    69181 taaactataa aattggtatg tggtcatacc agttttacat ttatataata gtaccattat
    69241 ctaccatttg caagaataat ttattttata acaaactttt aattttcatt ttttctataa
    69301 tttttactta taaaatccat atgttccttt gctttctcac atgcaagttc tacatcattt
    69361 tctacaactg cattgtatat agcttcatgc tgtttaagca atatattttc attaaaaggt
    69421 tctgcgatta ttttttctct tgcatcttct ataaatccat caaataattt tgatgctgtc
    69481 ataaaaagac tttgaattaa ataattttta cttaatgttg ctagtttact gtgaaatttt
    69541 tggtctaata ataccagtac tcgattatta tcttttttat tagtttctac cctcatttca
    69601 tctattatat gtttcaattc tataacttca gaagaagtta ttctctttga agcaagtttt
    69661 gcaatctcaa tttctaggat tattctaagc tctaatatat cttcaagtgt accattatta
    69721 agtttaaaaa tcatagataa aggttctatt aaagtttttt ctatatttgt acatataaaa
    69781 tttccttcac cctgtctgct ttctatcact cccatagtct ctaataccct aatagcttcc
    69841 cttatggaag ttctactcac attcatttgt tcagacagtt ctctttctga tagtaattta
    69901 tccccctttt ttaactctcc atttagtatt ttatattgta tttgctcaat tacttgttca
    69961 taaacttttt tactagctat actattaaac attttttcct ccaatatgat aatcgttgtt
    70021 gtaatatata tctattatat atcttaagcc attacattca tatattttta ttacttttaa
    70081 tataatatct tataactcaa atttacaggt gatattatga aaaaaaataa aattattgct
    70141 ttttttgctc catctatcat agttggagtt ctagttttag ggattatcct atacccaaat
    70201 gaagctataa aatctgcaag agaaggcttt tctatatggt ctaatgtttt agttccatca
    70261 ctactaccat ttataattgg agcaaactta attgttgatt taaaaatagt ggatattata
    70321 gggtttatca tcaatcccat aactagattt gtatttaatg tttcaggaaa gagcgcttta
    70381 gcttttgcta tatctacagt atctggttat ccagtaggag taagtttagc ttctgaattt
    70441 aggagtaatg gacaaatttc taagtatgaa gcacaaagac ttgtgtcttt ttgttctaca
    70501 tcaggacctt tattcataat aggttcggtt ggtacaggta tgttccaaaa ttcaaactta
    70561 ggttatttaa tgattctctg ccattatcta ggaactatat tggttggtct tttctttaga
    70621 aattatggta atgaaaacct tccaaagaca aaattggatt taaaaacaaa tataaaaaat
    70681 gtaatcaaca ttagaaattc aagtgggaat ggtttttttg ttttatttgg aaatgctgta
    70741 tttaatggag taaacacatt acttacagtt ggtggatttg taattgtttt ttcagtagta
    70801 tttaaaatac tatctctttt taatgtaatc tcattaatag catcagttat atatttgcct
    70861 ctttcatttt taggtgttag taaagaactc tgtcaagcat ttgtaagtgg tctatttgaa
    70921 attactatag gatgcaataa agtatctagt ataacaagtt ctccagaaat tttaagagca
    70981 tctttagcta gttttttgat aggatttagt ggattatcca tcctagctca atgttgtaca
    71041 tttctatcaa aaacggacat agatttaaaa ttatacatac taagtaaatt tgcgcatgga
    71101 gttttagctg ctatctttat atttatactt tatccaattg caaactctgc tgtgttggtt
    71161 tctagctttg ctgatacata caacgttata tataataatt taatctggtt ttattacctt
    71221 agctattatg atacaattct tcaaattgta gtaataattt atctaatctc agccgtattt
    71281 attgcaaaaa aacatatgaa aactttatct acaaatggga aactaatgcg atataaaaat
    71341 acttttttca ctaagaaatt ttcacgaaaa aaataaaact aaaaataaaa ctaataaaac
    71401 ttaactaaat acttccattt ttttattata tttgtcataa ttttaataac ctttttaatt
    71461 agtttaacag catagttatt tcatcacaat ttaataattt tattagaaat atttttcaaa
    71521 aaattctcct taatcacata tatcacactt gtataagttt actgggaaat ttttccatta
    71581 tataatattt catttatatt atataataaa taccgaccta aacttaccaa atcaaactaa
    71641 gaggagtggt tgaaaatggc aacaagacct atagaaatag acgaatataa aaagataatg
    71701 gaactattac atactggctt tacttatagt gaaaatggcg ttgaaaaaag atttagaaaa
    71761 aatcctaaag ttgcattggc actaatgtta gaagctaatt taggtctaag aatatcagat
    71821 attttaagat taaagatagg taattttaaa ggtaatatgt tggaaataaa tgaaaaaaag
    71881 acgggcaaat tacagtatag accagttaat aaaaatataa ttgagtccat aaatgaacat
    71941 gcaagaaagt ataatcttaa atcaaatgac tacttagtaa atataaagac aaaggctatt
    72001 caaaaacagt tgaggataat ttgtaaacac ttaaatctgt ataatataag tacacatagc
    72061 tttagaaagc tctatgctac tactcaattt gaaaagagta acaataattt agagttggtt
    72121 aaagaacttt taaatcacag ctctgtagcc actacacagc gatatataag ggtaactcag
    72181 caagctatta atgaagctag tgaaaatttc tttattggtt aattataacg tatacatttt
    72241 tctattatct tattaattca ccagatatta aaaaagagtg tctcaaaatg aactttttag
    72301 ttcataagac actctttttt tataaaatca aatatatttt tattatttca acactggaaa
    72361 aaaggcttat ctctctattt tgagacaccc tattaaattt tcataattct tgcataaaca
    72421 tattaatcta tcttcaataa ttttttagct gattcactgt aattatttct ttttacaatt
    72481 tccaaaactc tatcaatctc atgttctgac tttgcactta caaaaatcgc caattcttca
    72541 tcatctataa tatcataact atctacatat ttatctaaac attctaaaat tccatcttta
    72601 ttattatacc caccaaatct aactactgca ctacactcat cttctataag tccacttaaa
    72661 tccaatttcc cttttgaaaa agactttata tttgaacttc tattatctat tatatctata
    72721 atatctgcat aaacagcact tcctgttgca cctcttccag ctcccttacc tacaaaagaa
    72781 agttcaccta ctgaatcacc tactaaaata actacgttga actcattatc tatctttgaa
    72841 agcatattat tattgtccac taatgctggt ctaacaaatc cacttacttc tcctgattca
    72901 tacttacttc tagcaaccaa ttttatctta caatttaatt tttttgcata ttctatatct
    72961 ttttcatcta ttgaagttat tccttctaat aataaatctt tccaatatac tatttttcca
    73021 taagataaag tagacaatat agataacttt ctagcactat catatcctaa aacatctgca
    73081 tctggattaa cttctgcaaa tcccaactct tgtgcctgtt ttaaagcgac atcatacggt
    73141 aaattttcat catacatctt tgataatata aaattacaag tcccatttaa aatagcgttt
    73201 atgctcttta tattgttgcc ttccagtgat tctatcaatg gttttaaaac tggaatacca
    73261 cctgccacag atgcttcaaa cttgatgcta acattattta agttagctaa ttctataagg
    73321 tcactacctt tttcagccag taaatcttta ttagctgtca ctacatgtat ttttttattt
    73381 aacgctcttg ttacataatc aaaagctgga tttaatcctc caattacttc aactagtata
    73441 tcaatatcct tgtcaaatat atcttctata tcagtagtta tcttatcaaa gtacttctta
    73501 tacttgtgtt tttctttatt tttaactaaa attccaacaa cttctatatc tctttttgaa
    73561 gtattatttt ctattaaatc aattaatcca cttcctactg ttccataccc taatattgct
    73621 atcttcactg taacataccc ccatcatttt gattatatta aattatttat atatataaat
    73681 ataccaataa aaaaagcttg agtataaact caagccatat gacgggttta tactcatctt
    73741 tcagcataaa tgctgcagga tttagcacca atgtataatt aaatatactg gttgccgggc
    73801 ttcacagggc cagtccctct gccactcttg ataagattgc taatttaaat ttatgtttaa
    73861 tagtataata caatttcttc caattgtcac tattttttta acttatttcc ctaaaaggat
    73921 ataaactatt atctaacagc tcttttagtt ggtttaccct tttttgtaac attattattt
    73981 ttagtctttg ctttcgcctg ttcatgtcct ggaaaaagta ttttaggctc ttcaatattc
    74041 ctcttgtaaa tagtaaattt aaaaccaata gcctgcacaa attcagctct taaagcttca
    74101 catactgcat tagcagtttc tttagtatca agacctgcat tttctaatat agtaactttt
    74161 actaattctc tagttcttaa cataccatct aattgctcta agaaactctc tgtaacacct
    74221 tctttaccaa tttgtgtagt aggctttaaa gtatttgcca aagatcttaa atacgccctt
    74281 tgttttcctt ttaacatatt ctcacctcta taattctata cttaaattat ctataatcta
    74341 tatttaaatt aattgtaaaa ctcaaattct aattcataaa ttttaaccac atctccatct
    74401 tctattccca tttctctaag cctatcaaaa acaccttgac tctccatagc tttttggaaa
    74461 tattgaaggg attccatatc atcaaaattt acagaataca ttattcttct aagtgcttta
    74521 cctgtaacta catacacacc atcttcaata tctatactta actcttcttc agtaccaata
    74581 tcaagttctg gtctatacat ttcttcttct gaaactagct ccacatcttc tacttctttt
    74641 agcattttag aaacataggc tattacttca tctatgcctt gacgagttgc tgctgacatt
    74701 ttaaatactg tatatcctct gccttctaat tcactcttaa acttctcaaa cttactctca
    74761 tcttctaata tatcaaattt atttgcaact acaacttgtg gtctctttga aagcttttca
    74821 ttgtacaatt taagctcatc atttatcttg tcaaaatctt caatagggtc tcttccctct
    74881 aatccagata tatctacaat atgtatcaat acctttgttc tctcaacatg tcttaagaac
    74941 tcatgaccta atcctatgcc ttcagaagca ccctctataa ttccaggtat atctgcaagt
    75001 acaaaactat ctccaaactt agtttgaaca acacctagat ttggtgtaag tgttgtaaaa
    75061 tgatagtttg caattttggg tttagcttta gttacaactg atagaaatgt tgatttacct
    75121 acatttggaa atcctaaaag accaacatct gctatcattt taagttcaag agttatccat
    75181 ctttcttctc catctgtacc agattttgca aaagctggag cttgtcttac tgcatttgca
    75241 aagtgttggt tacctttacc acctatacca ccttttgcaa ctatagctgt atctccttct
    75301 ttttttaaat ctgctaatac aagacctgta gcctcatctc ttattactgt acctgctggt
    75361 acttttaata ctaaattttc tccattttta ccagctcttt ttcctttgct tccgtcgcca
    75421 ccattttgag cttgatattt tttctggtac ttaaagtcca ttagagttct aagccccaaa
    75481 tcaacttcaa atatgatgct tgctccacga ccaccatctc caccgtctgg accaccagct
    75541 ggaacgtatt tttctcttct aaatgctacc gaaccatttc caccatttcc agccttaaca
    75601 aatattcttg ccttatctat aaacaaattc ttcacctact taattaaaaa cttttaatta
    75661 gcattaccaa aaataccatt ataaattcat cagtattata agaaaaagga gtgcctcaac
    75721 actcctttta tgtatattac tcagctatag ctactggata tatactaact ttttttctct
    75781 tcttgtcttt tctttcgaat ttaacagtac catcaactaa tgcaaataaa gtatcatcac
    75841 taccttttcc aacattagtt cctggatgta ttttagttcc tctttgtcta actattatac
    75901 ttccagcagt tactaattga ccatcgaatc tcttaacacc taatctttta gatatagaat
    75961 ctctaccatt tttagaagaa cctacccctt ttttagatgc taataattgt aaattcatgt
    76021 ttaacatatg gagtcacccc ctactttttt aaaattttta tattttttgg gtattcccgt
    76081 ttaatttctt taaccgctaa ttgaaagtga tttagtaata attgtgcgtc ttttacatgt
    76141 gtatctttga ctatacactc tatatgacct tcttctccta ctactttttc aaattcaatc
    76201 ttttgtaatt tgtctaaaga atttataact gcaatagcat tagatgtaac tgcagcacat
    76261 actatatcat agcctatttc agcaaaatca gcatgtccct ttaaacaaaa accttgcaac
    76321 aagaaatcat cattataata atatttaact tttatcataa cttaaccaat aactaagcgt
    76381 ttattttttc tacaactatc ttagtgtatg attgacgatg tccttgtttt cttctgtaat
    76441 ctttttttgc tttatacttg aaaactataa ctttcttagc tttaccttgt tcaacaactt
    76501 tagcttgaac agatgctcct tctactactg gagaacctaa ttttaattct ccatctttag
    76561 agcaagctaa tacttcgttt aaagtaacaa catcacctgc gttagcttct aatttttcaa
    76621 cgaataatac atcaccttca gaaactttat attgctttcc accagtcttt actatagcgt
    76681 acattaaata cacctcctcg gcctcaaact cgccagtaca aggtacttca tttgaagatt
    76741 taaaccttta ctgtgcggca ttacaattat taattataaa atatttacat tttattgtca
    76801 actattttat cgaaaataac attggtttta ttgtgcttta atgtactatt tgcgtttaaa
    76861 gaaatcttta tattatattt ttcaccaatt ttatcaatta tatccatata atattctttt
    76921 atttgttcaa aaataaaatc attaaattct accattatgt ttttgtaaac agtatgttca
    76981 cttattctca taatttcttt ttcaatacta tctagtatat aatgtacaga ttttattgtt
    77041 tgttcaccat cacaacatgg acaagacatt aaataatact tatcaatgga ttctttttct
    77101 ctacgcctag caacttctac taaaccaagt tttgtcatac ctaatacttc agcttttctt
    77161 ttatctttat taaattcttc ttctaggatg tgtaaaatct ccttttgatg cttcttttta
    77221 tgcatatcaa taaaatcgat tattattatc ccagctatgt ctctaattct aagctgtctt
    77281 acaatttctt ttgcagcttc aagattagtt ttataaacgg tttcatcaag tttaccagtt
    77341 ccaataaact tacccgtatt tacatctata accgtaagag cttctgtttt ttcaattatt
    77401 aaataacctc cactctttaa ccatactttt ttatttaata atttttctat tttagattct
    77461 attctgtata aatcaaatac atctctattt tcctcaagac acagtttatc aacataagtc
    77521 ttatctatac ctcttaaaat agacttaagt tcagagtact tatcataact attggtaatt
    77581 atagattcaa tatcatcatt cacattatct tttacatatt tagttgcaaa atctaaagac
    77641 ttatataata atttcggacc tataccaagt ttatattctt ttaaaatgtt ttcatacttt
    77701 aatttcaact cttctatatc tttctttatt tcatcatgag tgcaaccttg agcctcagtc
    77761 cttattatta atcctagatt ttccttattt actgccttag taattttttt taatctaaat
    77821 cgttcttttt catcagtaat tttatttgat attgtagttc tatcattgga aggtatatag
    77881 acaatatacc ttccagaaat actaatctca gtgtttaatt ttgcgccttt agttcctatt
    77941 tcttctttat ttatctgaac caaaatatcc tgaccagatt ttatagtact tccctttttt
    78001 aattgtaaat aagcaagttt cttaaatcca atatctacaa aacaagcttc tattcctggt
    78061 ataacttttt ttacgattcc acgatatata ttggatacag tcttcttatt taaattgtct
    78121 tcaacaaaaa gttctgttaa tctttcatct tcaagtactg ctgttttctg ggaccctatt
    78181 agggactcaa taactatctt tttcacaact tcacctctcg agcttacata ggagtcacta
    78241 attccccatc ttctaataca tataaatctc ttctcaatat atcaacatct aatgggtcaa
    78301 tatcaagttc aaacatctct aatatctttg gtataagtat attagtattt aaattagttt
    78361 ttgagcctgt agctatagta gcagtaagag taatatgttc atcttctaaa tttaaaacat
    78421 caaaggttct tatcataggt cttatatcta cttcaaccat cttacctttt ttattctttt
    78481 ttgttatgat tatttcttta ttattcataa agtcaattac ttttcttttt acaaactctt
    78541 tcgtcatagg tcttttcaaa tctatattaa acaaatattc tccatagtct atcacagaag
    78601 aaagagaagg tgtttgtcta tcaatttctt ttgctttgat aaaatctatc ccatctggaa
    78661 gttgaattga tactttattt aaaaattcct ctactgataa atcatcttct tctatttcaa
    78721 tatctacata ctcaccttga ctttctgtcc ctaaagccaa agcattgcca taactcattt
    78781 tagggtgagg attaaatcct tgagaatgtg ataagtttat ttcagctctt ctaaacgctc
    78841 tttgtaacaa tctctgaagg tcaagatgtg atatatatat catgtcgcct tcctttttaa
    78901 attttactct tattatctta ctcatattag caaagccccc ttcctatatc atgtatattt
    78961 attccacaac cattgcagtt atgtctacaa tcagaagtga ttttttcttt tttagcattt
    79021 tcgtcttctc taattaagaa ttttttacta atacctacat ctatatggtc ccaaggaaat
    79081 acctcttcat agtttctatt tctatgtgca taaaaatcta tagaaagatt attcttttcc
    79141 atagcttctt tccatatatc taaattaaaa tgttctgccc atccatcaaa tttagcacct
    79201 agtctaaatg catcatatat aacttttcct attcttctat cgcctctagc tactactgct
    79261 tccatcaaac tagtctttga atcatgataa ttgtatttta tattgttatt tcttaattta
    79321 tttactaaat gtctctgctt attaataact tcttctgtag tatcttgacc atgccattgg
    79381 aaaggtgtaa atggctttgg tacaaatgta gaagtactca ctgtaacact aaaacttctc
    79441 tttagctttc ctccatttac ttttctataa atatcaataa ctttataagc taatttagct
    79501 ataccatcta aatcttcata agtctcagtt ggtaaaccaa tcataaaata caacttaaca
    79561 ctattccacc ccatctcaaa agctctttct gttgcatttt ccaaatcttc ttctgtaaca
    79621 cctttattta taacatctct aagtctttga gttcctgctt ctggagcaaa agtaagtcca
    79681 gattttctta cttgttgtat tttatcagca atttccattg aaaaattatc taatctaagg
    79741 gatggaagcg aaatcccaat attattagat gcatattcat ctaccaaata atcagtcaac
    79801 tctgataact tactataatc actcgtacta agtgatgata atgatatttc atcatatcca
    79861 gtattcttaa ctaatttatc taatatttct ttaagtcttt taacactctt ttctcttatt
    79921 ggtctgtata tcatacctgc ttgacagaat ctacatcctc tagtacatcc tctaaataat
    79981 tctagtacta ttctatcatg aacagtatct atataaggta ctattagttt ttctggataa
    80041 tctacagtct caacatcttt tattatcctt ttagtaggat ttttagtaat cccttctcta
    80101 ttaggagtta cactttgaac tgtaccatct tcattgtact tgacatcata aaaacttggt
    80161 atgtatactc cttctatgct agatatttta tataaaaaat cttctctagt cgttttattt
    80221 ttcttccatt ctttatactc atttactact tctaaattaa cctcttcacc ttcacctaat
    80281 attactacat ctacaaaatc tgctaatggt tcggaattat aagcacaagg accaccaacc
    80341 attataaatg ggtcttccaa agttctttct tcttttaata ttggtatatt ggctaaatct
    80401 aatatattta agatattagt gtatgaaagt tcatattgaa gtgtaaaagt gacaaaatca
    80461 aagtttgtta taggctctct tgactctaat gcaaataatg gtatactttt ttctctcatt
    80521 atattttcca tatcaactgc aggagaatac actctctcac aaaatacatc ttcatcctta
    80581 tttattacat catataatat atgactccct aagtgactca taccaacttc atataaatct
    80641 ggaaagcaat gtgcatatct tatcaattca ctattactag tatctttatg aattgaattt
    80701 atttcatttc caagatatct agcaggcttt tctacttttt ttaagatttt tttcaagtct
    80761 actttattca tttattaaaa ttcctccaaa caagctcttt atttttattc ttatttataa
    80821 gtaatattat acacgataaa atattttcta tcaaaaatat aactaaaata ttgaatttaa
    80881 aatacatatt attcacaaaa tagaatagct aaaaatattt aagaatattt tctattaaat
    80941 ttttattgaa atacaatttt tttacaaagt atgatatatt ataaacataa aactattgtt
    81001 ttacatgact tatcatgaca tcttttgttt cattcacctc aaaatggggt atgttactta
    81061 tataatgata aattttagga gggttaaaaa tgagtaaagt ttttgaagta aaaaaagata
    81121 tctactttac tggagtagta gatgaaggtt taaaagtatt cgacataata atggaaactg
    81181 agtttgggac aacttacaac tcttatttaa tcaaggacga aaaaacggtt ttatttgaca
    81241 ctgtaaaggc aaattttaaa gatgagtttt taagtaattt atcagaggtt actgatatag
    81301 ctaaaattga ctatgttgta attcatcaca cagaaccaga ccatgcaggt agtttaaaat
    81361 acttattaga tataaatcct aatatagaag tttattgtac taaagctgct aaactatact
    81421 tagatggtca aataaataga ccttttaact gtcatgtaat aaaagatggt gaaattttaa
    81481 atatcggtaa aagaaatctt agatttataa ctgctccatt cttacattgg gttgatacaa
    81541 tgtttactta cattgaggag gacaagactc ttttaacttg tgatgcattt ggttgtcact
    81601 ttgcaagtgt tgatgcagag gtagtgaata gtgaagatta tctaaaatca gctaaacact
    81661 actatgattg tatagttaag ccatttgcta aacatgtttt aagtgctgta gataaggtgg
    81721 taggactaaa catagaattt gatactatat tgacttctca tggtccaatg cttactaaag
    81781 acccaatggc tgctgttaaa agatatgttg agtggtctac agaagctgtt aatacaacta
    81841 atcaaaatca agtttctata ttctacttat cagcttatag taatacttta gagatggcta
    81901 aaaagataaa agaaggactt gataaagaag gtgcaaaggc tgaattatat gatttagaag
    81961 atatgacatt aacagaaatg cacgatacat tagtagtgtc aaaagtaata ttactaggtt
    82021 ctccaactat aaacaaaact atggttaaac ctatgtggga tttattctct gttatagacc
    82081 caatggctaa ccaaggcaag atagcaggag tatttggttc atttggttgg agtggtgaag
    82141 gtataactat ggctgagact ttacttaaat ctatgtcatt caaaatgcct gtagaatctc
    82201 ttaagaaaaa attcttccct agtgaagaga cattaaaaga gtgtatggca tttggtgcag
    82261 aatttgcaaa attagttaaa tagccattaa tcaaacataa tattatttaa aataaatgat
    82321 tttatattta aaaataaatt aaaatggagt tgtctcaaaa ttaatttttc taatctaatt
    82381 ttaagttcaa ctcctttttt attttctaaa atgactgata taatgataaa tgcacccttt
    82441 gtgcgagggt gcattattta taatatgttc tatttgtaca ctagtatatt tgtattaatt
    82501 cacatatcta gcgtatgcta ccatccctct tccagaatta gatgccgttt caccaatttc
    82561 cactttaata attacattat tttctttaca cttttttgat aattctgctg cagaaaggtt
    82621 cttaccagta aaatctaaag aaaatggctt atcatattca aaaggatact catcaggtac
    82681 accatctgga gctaatgcaa ccataccata tggtgtattc ataaacccta ttacagtaac
    82741 tgtatgcttt gatgggtcta aatttgaatt tttgcttgta aacttaattg tatttattga
    82801 tgagttgatt aaactacacg gaactccctc atacatttca atttttggac gtagattatt
    82861 tccataaact tcatcaagta ttgccccttg ttgatctgct atcatagtgt gattcccagg
    82921 tccaactggc gcagaaggct tagctggcgt aggtttctta acagttggcg ttggattctg
    82981 tgtctttact acttcgccaa cagctggata tgctttcttg tcaaatggta atgggtgagt
    83041 aagactcttg tatatgatgt ctgctcctgc tgatttgttg gcatcaatat ctacatgata
    83101 caaacgtcca tcctcaaaac gaataagatt ccactgatgg tcatttgttg tactatgtac
    83161 ataataacat tcaattccca tagcatcaca taaagctttc aagctcctac acattccaga
    83221 acaagcacct tttttagtaa ccaatgtata agcagtattg gctccctctg ctgcgttcca
    83281 gttaacatat gttgtgttgt ttttaatgtg attataagca accctaatct tagcatctgt
    83341 ggtcatgttc tttgtaattt tcttgttcat aaagtctgct gttgcttgtg ctaccgaatt
    83401 aagttgagct tgtgataact ttggaccata tatactgttg gttccagcta cataactttt
    83461 cggtgtcttt gcagtaacat ctttagctgt cataccataa actgttacac tcatacatga
    83521 ggttaaaacc atcattgcaa tcaatagttt agtagctaat ttcctgattt ttttcatatt
    83581 agcattctcc tttataatat attttacttt caattcccta ccattaatta agttcatttt
    83641 agatttaaaa tatggattat caacatgtat gcatagcaat tcacgtggtc atagaatatt
    83701 tagatttctt ggaaaatctg ttctatattt cctatatagt tcgtatacaa tccaactcac
    83761 aaacctgcat ttttgatatc atcacaataa aatgataata attaatatat tcaaaaatgt
    83821 tggtctgtaa caggtatgtc aattttccaa ttattggtaa tggcgagagt gaggagaatt
    83881 gtcaataata catttaaaat taaaattgta tacacttcat acattctccc ctaacaacat
    83941 tatacagatt ataatttgta tattcaatac attttttgga aagtataatt atatcaaaat
    84001 atgtgattat gtatagatac aatccactat ggagaaatat aaaagaaaag agtataacaa
    84061 acaataaaaa ataagatgat tcaaatttta ttttgaaaca tcttatttac tctacaaatt
    84121 aagattattt ggtgaattat ttaattatta ttttttatta aagaaatttt aaatcttaat
    84181 ataaaatacg ctattataca taataatcca aatgcaaatg ctactggaat taacatctcc
    84241 gattcaaaat aaaagaaata ttctaagaaa atatctggat ttactatatt cccattcttg
    84301 tctaaaaaat cttttccatt atatcctaaa tgctgtataa aattacttat gttattataa
    84361 tctgcttccc tctcatatac catattagca ttcaatccag aagaacttaa attagtgttt
    84421 ccatctttca tatctattac atatagtcta agagctttga ctttactata cttatcttta
    84481 tcaagtattt tttcaagttc taacttatat tcaccaatct ttgtcatatc atgtctttct
    84541 gccaattgct ttatttctcc atcaagttct tttcctaaat tatacatatt atgttgtaaa
    84601 ctattattgt aataccacat aaatccagaa attaaaaatg caattatact tatgtaacct
    84661 aatacttttt taaaccccat tacaattgat ttatgcctat ccaatgataa agatagttct
    84721 tttattatat tacataattc atactgcatt tcatcaccat catcaaatct ttcaattgct
    84781 tttttacatg cttcttcttc atctaatcct tctaatttaa attcatttgc agattctata
    84841 agatggcatc tcatttcctg ttttaattct atagtacttt tattgtcaca ttttttatat
    84901 agtttatcta aatattcatc tattagtttc ataaattaat ccacctctcc caaaaattga
    84961 ttcataacct ttttaataaa tctccattct tgtttcttta tttctaaaaa atctttacct
    85021 tcattagtta aattataata ttttcttctt ccacctgaac tttgttcatt gctataataa
    85081 gatttaatta aatttttaga ttccattctt ttaagtgcaa gatacattgt tccttctttt
    85141 aattcaaact cacttctttc tcttacttgc tttgcaattt catatccata acaatctttc
    85201 ttttctaata tagaaacaat taatatatcg atataacctt ttaacacttc tttatttaac
    85261 tgcattatgt accaccgcct tttcacctac tactctataa tgtatagtac ttatatttac
    85321 tataataata catagtactc tatattgcaa ggtttatatt ctacaataga cttaaaaata
    85381 ataaatagct gtatattaat atttaatcta taaatactaa tatacagcta tttatcaaat
    85441 tttaaaaata aatttttgtt ttattaatgt tgtcataaca acatttactt ggttgaaata
    85501 gtattaccta taagtttaaa tatatataat aatagacttg attctatttc atattattaa
    85561 aatagagtaa tagtttaaat tctactactc tatctataat ctatttccta attatttaat
    85621 ctcaaattta gctcttcatc atttaaatct ttcataagat ttctacaggt actagattta
    85681 ttccaacaga aagactaggg cattaaacac ttatatatct gtttctttag actgtaatat
    85741 taatattttt taaatacgtt gacttttgct ttttctaact tctctccatg atagttctcc
    85801 tctatcaaga gcttttataa atatttctgc tgaagctaga tttgtagcta ttggaacatg
    85861 ataaacatca caaagtctta ttaacgcttg tatatctgtt tcatgagcct gagatgtcaa
    85921 tgggtctctt aaaaaaataa ctaaatctat ttcttgtgtt actattaaag aacctatttg
    85981 ttggtctcca cctaaaggac cagatgctaa tctatttata tttaattcag tttcatccat
    86041 tattcttttt cctgtagttc cagttgcata tagtccatac ttttttaaaa ttgattcata
    86101 acctatacaa aatccgacca tagtgttttt catttggtca tgtgctacta atgctatatt
    86161 catatatcta atctcctcaa tttatgttta gatgtattta aatttagaaa tttattttct
    86221 ttcttctcat acacacattt agtactaatc ctaagtttgc taaagatgtc aataacgaac
    86281 ttcctccata acttacaaaa ggtaatgtta ctccagttac tggtattaac gcaaccgtca
    86341 tacctatatt ttggattatc tggtaaccaa acattcccat aacaccaacc actatgaggg
    86401 ttccataaaa atcttttgca tctcttgcaa ttgctaaaag ccttaatagg aatatcataa
    86461 ataagattat caacactgcc attcctatta caccaagttc ttcacctaca acagcaaata
    86521 taaaatcact atcttgtaca ggtaaaaaat cttcttgatt ttgacttcca ttgtaaagtc
    86581 ctttaccagt tacgcctcca gaaccaattg caatcagaga ttgcataact tgatagtttc
    86641 cttttagagt tacatcttct ggatttagaa aagcttctat tcttaccttt tgatggtctg
    86701 ccatcattaa atacatcagt ggcattgaca ctaatagtat gattattcct ctttttatca
    86761 actttgagct aagacctgct gtgaacagca ttgcaaatat catacaacaa aatacaattc
    86821 ctgttcccaa gtctggttgt gcaatcaata atccgataaa tggaagagaa taaactacaa
    86881 caggcataac ttcctttaac gtatttaatt tatccttttt ggattcaagt atctttgcat
    86941 aacttagtac aaatgttaat ttgactattt cagatgtctg caagtcaagt ggtcctaagt
    87001 taatccacga cctagctcca ccttttactg tcccaattcc aggtaataaa actatggcta
    87061 acaaaataag acttattata taaagcgctt tataatacct gcctagaagg ttatagtcaa
    87121 aaaataatat gactataatc attcctatcc caagtacaaa agctaatcct tgtttaatca
    87181 attgattata tgaacctgtt gaattagcat gtgttgcact actaagtata acaagcccaa
    87241 aaataaagat agctaatact gtaactataa gtttccagtc taactgtttt atcaacttaa
    87301 ttgtcgactt ataattaata ttgatttttt tcaaagaatc accgtctttc tatctttaaa
    87361 catataatta aataaaaggg gcatatacca ataaggatat ccccctttta agcactaatt
    87421 acatacatct atcttttata ttctttagtg gtatattagc aactaatgca gatacaggtt
    87481 tgtcatcatg ctcacctctg catttagaca tttttatttc aagaccatca tcttctattt
    87541 ctgcataatt agctattact tttaaaatgt ctgtttttat catctctaaa agttgtggtg
    87601 aacaatctac tctatcatga actaaaacta gctttaacct ctctttagca acagatttac
    87661 tagttttagc ctcgttagaa aaaactctaa ataaatctaa cacagatgta tcctcctttg
    87721 ctacttagcc atgctaaaca tttttttaag tctaccaaag aatccatctt caacttcaag
    87781 atcaagtaga ggaacttctt catttagtat cctttttgcg atatttttgt atgcttgacc
    87841 agcaagtgac ttagaatcaa gtatagctgg ctctccttta tttgttgata taattatgct
    87901 ttcatcatca ggaacaagac ctaacaaatc tattgctaat atttctatta tatcttgttt
    87961 atccatcatg tctccacgct taaccatatc atttctaatt ctatttataa ctaatcttat
    88021 ctcttttatt tcatttgctt ctaatagacc tattattcta tcagcatctc ttactgctga
    88081 tatttctgga ttagtaacta caatagctct atctgcccca gctactgcat ttttaaagcc
    88141 ttgctcaata cctgctggac aatctattat tatatactcg aaagattctt ttagtttctc
    88201 acacaggtca atcatctgct caactgagac agcattttta tctctagttt gtgctgctgg
    88261 taataaatat agattatcaa atcttttgtc ttttattaga gcttgcttaa gcctacaagt
    88321 tccttcaact acatctacta tgtcataaac tattcgattt tcaagaccca ttactacatc
    88381 taagtttcta agtccaatat ctgcatccac aactactgtt tttttatttt ctaggcttag
    88441 cgcagttcct aagtttgctg cggtagtagt ttttccaacc ccacctttac cagatgttat
    88501 aactataact tcgctcataa tactaccccc tatttttctt tctatttgtc taactttgac
    88561 aaatagcttt cgattacaat tcttccatta cttacaaagg ctatttctgg gctaatttct
    88621 gattcacttt cataattttc ttcatcatct ggagcttctg caatattatc tgctatttgt
    88681 aatattttag gattaagatt tccagcaaca acatatgcaa attcattgcc ttctgcacct
    88741 gcatgtacaa aaccttctat tttacccatt acaaaaacat tacctcctgc tacaacctta
    88801 gcaccagcat ttatatctcc cataacaact gtatttgatt ttgaaaggac ttttgaacca
    88861 ggtttcatat cattcaatat aactacatca ccttcaaatt caatattttc accagatctt
    88921 agggtattga catattttgt tggaaaatta ctattttctt caattttttg atcttcaaca
    88981 aattccacat caaatctaga agtaattcct tctttaagtt ctagaatctc catgtcagtt
    89041 aaacaatcac tattaatttt actaatttta gccccattaa aaaagccaac atatgcttcc
    89101 aatttgttta ttattttttc ctgtatttcc tcaaatggag cttctctttt tatatttact
    89161 attatccctc ttttattacc cttgaactct actagttctt gactacaaat ttctcttaaa
    89221 gacataacaa cctccagagt gatatatcat ttatattctt caaatacgct ttaaaccctt
    89281 ttattttttc tatataaagc taaagtttat acatagattg agctatctat taatttgtga
    89341 ctcgaaattt atattttcgt cagaagaatt gttaacatca ttcgtcttgt tgtcattttt
    89401 actattagtt ggctctaatc ccatataagt tccaataact tctctagttg gtaaaagtga
    89461 gaatacactt gaatcacctt gaggaattac acatacaaca gctatttctg ggtcatctgc
    89521 tggagcaaaa gcaacagtcc acgtaaaaga accataatct tgtttaaatc tatctatttg
    89581 gtcatctgtt atttttggat ttaattcttt tatagctttt cttagatatg aagaattcac
    89641 cttatcagtg tcctctaatc taacttttac tccatcttct aattcttcct ctaatttctt
    89701 tctttcttcg tctttcaaat ctttattttc taatttcttt tttatttcct tttccttagc
    89761 taatgaaagc tctttttctt tttctgcttt catcttatca gctagtttaa tcgcatcatt
    89821 taggttgaca ttataagatg acatatgact ttttaaatat tcatactcgt tatctgtagg
    89881 tattttccca cttttctcag ctgtaccagt ttttgctgct acatctattg gaaaatcagc
    89941 aaaagcactc ttcgctgtac cttgtcttgc aaccaatttc ataccttttg ttaattcttt
    90001 taagttatct ggatttttaa aaggtatttt ttcgactttc ttctggtcat taattttaac
    90061 tgatgaataa tcacttgaaa cagctctatc aactacagat aattctacta aattacctcc
    90121 atttgctata gcagctacat atcttgatat ttgagctggt gtataagcat tttcaccttg
    90181 tcctatagct aagttgaatg tatctgcagt actccatttt gcaaaattaa aataactaaa
    90241 tactgctaaa tctgctactt cttcaattct atcttcttta acatccaatt tttttagcct
    90301 attcattgtt tcaactctac caggagtttt cttttctgct gcccagctta caatctcatt
    90361 gattcttttc tcatattctt taggattttt ttctctagtt atatcaacaa aatcatttgc
    90421 catttctctt tctaaatttg actttagaag agcttgtgtt gatttcaatt tatcttctgt
    90481 gctaggaact ttacctgctc tttcttctac ttcatcttga agccctgtat tttggtcaag
    90541 cccaaataat tttgcatact caagtatttt atttgcattc atatctatac caatgctttt
    90601 tccatctggc catgttttac ctgtaccaat tgttgccata tatatattac aagactcttg
    90661 tattgcttta tataagtttg tcataccatg gtttcctcta ccatggttcc atacatagtc
    90721 accaaaagat tttttaccta acattataac cccagggtca tttatagtaa agtttggatc
    90781 cagaccattt tctaacgctg ccattgaagt taccatctta aatgaagaac ctggctgaaa
    90841 ttccccttgt gtaaccaagt ttaaaagtgg acttcctgct agtaagtcat ttggattttt
    90901 tggttgaagt gctttataat cctctgtaga aatacctttt gcaaatttat ttgggtcata
    90961 attaggataa cttgatgaag ctaatacttc tccattttta acatcaatag ctataagagc
    91021 tgctgactgt gcttttcctg catatgcact aattggtttg tccccaaatt tacttttaaa
    91081 agtacctcct ttagaagcaa cttcgattat ctgttttaat gcattatctg aaacttcttg
    91141 taaatcttta tctagtgtaa gatacacagt atctcctgat ttaggttttt tagattcaat
    91201 ttctttactg attctaccca atgcatcaac tttaaccatt ttataaccat cagttcctct
    91261 taatctactt tcattactct tttctactcc tgcaagacct accatatctc cagtttcata
    91321 acctttttga aggtatgatt ctatttgagt ggatggcatt tttcctacat atcctaacat
    91381 atgagaagct aatgacccat taggataata tcttactggt tctactgcta ttgaaacacc
    91441 aacaaggtcc atagcacttt cttcaatttg agcaatcgta gtttctccca catccttagc
    91501 aatagttact ggattatatt gagaatatcc ttttgatttt atcaaatccc ttacgaccat
    91561 tatttttctt gcatcttcat cactcaaact tttatcaatt tctaatgcat cactatttct
    91621 tactttttca aacgcttctt tggcactcag tttagtttct tttatcttat aactagccaa
    91681 ccaatctctc ttatctcttt ctgctgtgaa catccattta ctaactaaaa taggtggata
    91741 atatccattt tcatttagtt ttgcctgtaa tcttgtcgca tccaatcttt tatcttcttg
    91801 agataatatt ccagctgata taagtttgtc caccaagtaa taaaaacttt ccttagcatt
    91861 ataatcattt ggaataccat tttctgattt atattcccta atatctctgt catatgtata
    91921 atagtacttt ccattttcta catatatagg aaactcatct acatattctt caccatttct
    91981 ctccagcaaa tttataagtt ttaatgatat ttcatttgct cttgaatgct tatttgcatc
    92041 tttcttatta atatcgttac ctgaaacttg aacagtaaat aagtttttat ttcctgccaa
    92101 cagtcttcca tatctatctt ttatttctcc tcttggagct tctattgcca actttttata
    92161 tgttttattc tcagctaact cattgtaata ttcatattta aatgtagtca tatagattat
    92221 ttttactaaa atagctaaaa atatcacgcc catgactatc ttaattattt ttagtctatc
    92281 aacttgttta ttttcttcca tgaaatcacc aactaatctt ctttaagttt taaaactgct
    92341 cttttagata agcgatatat tactaaacca attaaactat tcactattgg tgctactagt
    92401 agacctttta caaaaagtgt tgatatgttg tagctttgat aaattatact agatgtacct
    92461 atattgacaa ttgaatcaat taaactgcct ataaaaatta aaacgaaagt aataatataa
    92521 ctacctttat atagctgatc tctcatgtat ccaattgcat atgcaataat aaacaaaatt
    92581 aatgcattta caccaaaaat tccaccaacg gttatgtctt taataagccc tattattgct
    92641 gctataatcc caccttctaa ttcatctaaa taaagagaga ttatggttac atatataaga
    92701 actaaattaa agcttatgcc aaaaatatct atataatttg ttatactatt ttctatagtc
    92761 ataagcacaa tccccaacag acaaagtaaa acttttttca ttgtttttat cccctttatc
    92821 ctatatttct tggttctatg actacaacgt catttatatt cttaaaatca acataaggtt
    92881 ttacaactac atattttaat gacttatctt tatcatcaac cactttttca acttcgccaa
    92941 ttggtatacc atctgggaag aatccaagac ctgatgttgt tattatatct ccttgaatta
    93001 cattatatga tgagtcaaac atatatcctt gcaaatatcc tttactatta taactatctt
    93061 tattatctaa agtagtattt tgagtaattg tacctttagc attggcatcc tttgctagtt
    93121 taaagcttac agatgcctta gaatccaata gtgaaattgc cttactataa ttgttggaaa
    93181 cctcataaac tatgccaact aatccactac cattcataac tatactttct ttttttacac
    93241 ctgaattttt tcctgcacct atgacaaaac tctcatacca gtttccatca tttttaccaa
    93301 caacacttgc tgaaatactt gtcgccttat actcttcttg tacaaagttc agtgtctttt
    93361 ttaactcttc tagcgattct gttttatcta gtttggcatt taaagctatc atattttttt
    93421 taagtttttc attttcttct tctaattttt ttaccttttt agaattatct ttaaaatttg
    93481 ctacatcttt aaaaccattt ttgataaaag aaaatccatc atttattccc ttacctacac
    93541 ttgtaatagc atctgaagct actcctaaat ttactggact accactagaa aatttaccaa
    93601 ttgatatacc cacaattcca attaaagtga tagcaactac gcccgttgct atcactttaa
    93661 cattaatcct ttttttctca tttttgttct tgtcaaatct caaggccatc accaacttct
    93721 aattcttagt attcatcatt aatacttttt caaagatttc ttggtcttca acagatttac
    93781 ctgttccaag tgcaacacaa tcaagaggtg tttctgctat ttgtacagac ataccagttt
    93841 cctgtgtaat aagcttatca agacctctaa gcaaagcgcc tcctcctgtt agcattattc
    93901 cgttttccat tatatctgag gctaattctg gtggagttct ttctagtgta gattttattg
    93961 catctactat tgaacttaca ggttctttta atgcttctct aacttctgta gagcatattt
    94021 ctattgtttt aggtaatcct gagattaaat ctctacctct tatttgcata tttatttctt
    94081 catcatcttt aaatgtagaa cctatgttaa tttttacatt ttcagcagtt ctttcaccta
    94141 tcataagatt atattctttt tttacataag ccactataga ctcgtcaaat tcgtctccac
    94201 ctattcttat agatttagca gtaacgattc ctcctaaaga tattacagct atttctgaag
    94261 tacctccacc aatatcaact accatattac cttctggttc ttcaactttt aatccagccc
    94321 ctatagccgc tgccattggc tcttctataa ggaatgcatc tttagctcct gcttgtcttg
    94381 cagcctcttc tatagctctc ttttctactt ctgtaactcc aaaaggaaca catatagcta
    94441 ttcttggact tacaacacct tttttatcag ccgctttttg tataaaatag ctaatcattg
    94501 attgagttat gtcaaaatca gctattactc catctttcat aggtcttata gctactatat
    94561 ttcctggtgt tctccctatc atttttttgg cttcttcacc tactgctaat acctctttac
    94621 tatcatctct tattgcgaca actgatggtt ctctaacaac aataccttgt ccttttatgt
    94681 aaactaatgt atttgcagtc cctaaatcta ttcccatatc ctttgtcatc ttattaaaac
    94741 taaaaaaacc ttttttttct ttcttttttt ccttagccat gattttactc cttcctacta
    94801 ttaagaatca tgtttaaaac attctcctat tattttatca catataaagt caaattatca
    94861 tattttcttt aaagctaaag tataatccat ctccaataat tatatggtct attatttcta
    94921 ttccaattat ttctccacat ttaataagtc ttgatgtgat atttttatct tctcttgatg
    94981 gttctacact tcctgaaggg tgattatgca tcactattat cttacttgca cttcttctta
    95041 tagcttcttt aaaaacctct cttggatgga ctaatgacga gcttaaagtc cctatagata
    95101 catctacatc agatattatc tcattttttg tgtttaaaag aaccgcttta aaaacctctt
    95161 tttttaaata ccttaggcta tccatataat acctctgtat atcccaagga ttccttattt
    95221 tatactttat aggtttaaaa ctagctactc tagagcctag ttctaaagct gctttaattt
    95281 gggttgattt tgataaccca attccatcta tattacacag ctcctctatt gtcatatctt
    95341 ctaaatgtct aataccctga atatctctat ttattatata gttggctaat tcaatagcat
    95401 ttttattctt gttgccagtt cttaaaagta tagccaacaa ctcagcattt gataagcttt
    95461 ttacgccttt ggcaagcatc ttttctctgg gtctttcctc tggtgccatt tcttttacct
    95521 taatggttga attaaatgac tttttcagat aaatcacact ccataaaaaa gatttatact
    95581 aaaatatttt tttaataggt cgcctaacct tgaaattgga agaccaacta tattaaaata
    95641 atctcctcta atttcttcaa ctaacaaagc tccataaccc tgtataccat aggctcctgc
    95701 tttgtcaaat gactcattag ttttcagata atcctcaata tcctgctctg ataacgtttt
    95761 aaatttcaca ttgctgatta catagtcaat taccttttta tcttcgcaca agtttattaa
    95821 gctaatacct gttatgactt gatgctctct tccagatagt ctttttaaca tatctcttgc
    95881 acaagactca tcttttggtt ttcctaaaat agcattgtct aaaacaacaa ctgtatcagc
    95941 tccaataaca acatcttcat tatgttcaga tgctacagac atactttttt caaaagctaa
    96001 tctcataact aaatgttttg gtgtttcacc ttccaatata atctcatcaa tttcattttt
    96061 aattatatca aatcttacat tcgtattctc tagaatttct ttccttcttg gagaggctga
    96121 tgccaagatt atattcattt attcacctca tttgtacgta atttgtacct atttagtcta
    96181 tcactatatt gtaaaaaatt caacagaaat gtcgaacctt ttttgttaca ctattgttat
    96241 atttattacc attagaataa atatacataa aatagaggta tggaaattat tccatacctc
    96301 tgttttatgt actcattaga gatatggaaa ttattccata tccttatttt gtccatatta
    96361 caaaatttta atagctttct ttggacattt ttccatacat aaatggcatc ctacacattt
    96421 atctgcatct accttatgtt tttcttttaa ttctccctct attgcatcaa acttacattg
    96481 ttttttgcac actgtacatc caacacaaag ttcttggtca atagtaactt tctttttctt
    96541 agttatgtca cctgatatta cttttgtagg gcattttgct acacattgca tacaacctac
    96601 acacttatta gggtctatct tagctatttt gtcttcaaat attattgcat caaatttaca
    96661 agcttttaca cacattccac agccaataca tccagcagta catttttctt taacagcttt
    96721 accaaactct ttgctattac actctacaac tacttcttga ctttctggtt ttgtgattat
    96781 tataccctta ggacaaactt ctttacattt tccacaattt acacactttt cttcatctat
    96841 tactgctatt ccatcaacta tagaaatagc atcaaattta caagcatctt tacatgttcc
    96901 aagacctaaa catccaaatt tacacatctt agcacctgag tttaaaacat ttgctgctct
    96961 acaatctgat attccttcat actcatattt atcttttgca cttgaacaag ttcctttaca
    97021 aataactttt gctacttgtt tctcacctgc ttcagcactt attcccatta tttctccaac
    97081 ttttgcacca acatctgctc cacctacagg gcaaccatta actggtgcat tgccttcaac
    97141 tatcgcattt gcaagacctc cacaacctgg aaatccacaa cctccacagt tggctcctgg
    97201 aagtactcct agtatagctt ccactctctc gtctacttct acagcaaact ttttagatgc
    97261 aaaatctagt actatcccga agattaagcc cataattcct aaaactaata cagctgtaag
    97321 tatcaccatt ttcacccctc ttttttatag ctttataagt cctgtaaatc ctaagaaagc
    97381 tattgacatt aaacctgctg atataagcgt tatagggaaa cctttaaatg cttctggtat
    97441 atcagctaat tctagtcttt ctcttatacc tgcgaatatt actattgcta aagtaaatcc
    97501 agctccggct ccaaatccgt ttattattgt ttctactaaa ttataacttt tttgaacatt
    97561 aactagagct ataccaagaa ctgcacagtt tgtagttata agaggtaaat aaactcctaa
    97621 tgcttgatat aaagatggac tcatcttttg aattaccatt tcaacgaact gaactataga
    97681 agctataacc aatataaaag ctattgtttg taagaatcca gttccagttt ttactaataa
    97741 aatctgtata aaataagtta taattgaagc tagagttaaa acgaacgtaa ctgcaactcc
    97801 catccctact gctgtatcaa ccttcttaga aactcccaag aaaggacata tacccaagaa
    97861 ttgagatgtt ataacgttat taacaagaac gatacttaaa aataaaagta ttaaattcat
    97921 ttattacacc tccactatgc ttttttactt cttaatttat taaatcctgc aaataagaat
    97981 cctaatgtta agaatgcacc tggtggtaat ataaatatta atactggttg gaaagatgct
    98041 ccaaataatg tcattccaaa taaactacca tttccaagta attctcttac tgcacctatt
    98101 attgtaagtg caacagtaaa tccaagacct tgacctacac catcaactat tgaaggcata
    98161 gctcctgttt tgaaagcaaa actttctgca cgagctaata ttaaacagtt aacaactatt
    98221 aatggtatat atataccaag agccttatca agagcaggaa catatgcttt taaaagcata
    98281 cctactattg taacaaatgt agctataact actataaata taggtattct tatcttatct
    98341 ggtgtaattt ttcttattaa agatataact aaatttgcac atattaaaac tgctgctgtt
    98401 gaaagaccca taccaattcc atttattgct gaagttgtaa cggctagtgt tggacacata
    98461 cctataactt gaacaaatgt tgggttctca tctattagcc catttttaaa tactttagct
    98521 aaattcataa ttaaccctcc ttatttatta agagcactat tgaaaacatc tatagcagca
    98581 tttactcctg tagtaactgc tgtagatgta atagttgcac ctgatattgc taatatttga
    98641 ttatctgctg ttgtacttcc ttttgctact tcaagaggct cagcagtttt tcctttgtat
    98701 tgacccttaa atgcatcatc cttagctttt gctccaagac ctgctgtttc tgacatatta
    98761 ccaatgtcaa cacctgtaac ttgaccttca gatgatatac ctaccataac ttcaatttct
    98821 ccaccatatc cacttggttt agcttttaaa gtatatccaa ccacttcaga accatctaaa
    98881 ccttcataca cttcagctat aagaccatct ccaaggcctt tgtaagtatc ttccttcatt
    98941 tctttaaatt cttttgcttc tggaaggact gcttttctaa gttcattatt tgcttgtata
    99001 tttctttgtt ctattactgg agctgtaacc tgattagtag ctccaagagc taatgcagct
    99061 attgcactta tagcaagtaa agtaccacct aatctcacca tactgttcat tatttagcca
    99121 cctccccaaa tactctattt ctaacaaact tatctataag tggagcaaga cagttcacta
    99181 atagtattga gtaagataca ccttctggat atccaccata cattcttata acagttgtta
    99241 taagaccagc taatacagcg tatattattt gacctttttt agtcataggc gaagttgtat
    99301 aatccgtaag catgaagaat ccacctaaca taagtcctcc agcaaacagt tgatatattg
    99361 cgaaagttat attaaatcca cctaaaagga atgttaatat aaatacagtt gctatgtaaa
    99421 atactggtat aacataattt attatgcctt tatacattag gtatactcca cctaataata
    99481 ataatattgc tgatgtctca cctatacatc caccaatatt ccctatcatc atgtcagcaa
    99541 gactaattcc attgctagaa atatctgcca gtcctgctgc tccatttttc aaaaagctta
    99601 atggagttgc tgtagtaact gcatctaaat ttttacctat ccagttaaca cctggttgag
    99661 tccaagcagt cattgctact gggaatgatg ctaataaaaa tgctcttgca gcaagtgctg
    99721 gattgacaaa gttacatcca attccaccaa ataccatttt aactactaat attgcaaata
    99781 ttcctcctac tagacacatc caccaaggaa gtgatgctgg tacgttaaat gctaataata
    99841 atcctgttac aacagctgaa aaatctccta tagtactttt ttgcttcgta aatttttgat
    99901 ataaaaattc agtacctact gtaccaagta tacaaaaaaa catagcactc aaagcattaa
    99961 gtctaaagaa gtatactcct gctactgctg ctggaaggag tgctataata acttgtttca
   100021 ttatatatga agtatcttca ttacttctca catgaggaga agatgatact atcaacttat
   100081 tttccatcgt ttttccccct taactttctt tatttctgag cagcttgctt tcttctcttt
   100141 gctcctattt ctctctttgc tgatcttata gattgaagta atggtcttct tgctggacaa
   100201 ataaatgagc aagacccaca ttctatacaa tccattgctc tatgatattc agctgtgtca
   100261 tagtcatctt ttaaagaata tgcacttatg aaaagtggtt gtaagaatga tggacataca
   100321 tctgtacatc ttccacatct taaacagttt tgaatatctg gagtacgtga ttcttcctca
   100381 tccaaacata aaattcctga agaacctttg ttagtcgcta tttcagtagt atattgagct
   100441 attcccatca taggtccacc cattataacc ttaccaatct tcttatcttc tttaaatcca
   100501 ccacattgtt ctattatttc tgaaactaat gttccaactt ttgttattag gttctttggc
   100561 tctttgatgc aactacctgt tattgtagtg attctttcaa ccaaaggcat acctgtttta
   100621 atagacttag ctatctgtgc tgctgtggca acgttgtcaa caactgcacc tgctgctatt
   100681 ggtaatccac cagatggaac ttctttgcct gtacacgcat aaataagttg tttctctgct
   100741 ccttgtggat atttcacttg aaggccaaca acttcgattt cgctatagtc tttagctaca
   100801 ttttgaattg cttctatagc atctggttta ttcgtttcaa ttcctataaa tccttttttg
   100861 acatctaata ccttcattaa tgctcttaaa ccaaacacaa catcttctgg attttcaacc
   100921 attaatctgt ggtctgcagt taagtatggt tcacattctg caccatttaa tataactact
   100981 tctgccttgc tatctggtgg aggagatact tttacatggt tagggaatgt agctccaccc
   101041 atacctacta ttcctgcctc ttttatgata cctactatat cttctttgct caaatcctct
   101101 aactgacctt ttggttgaac actctcatgt aattcttcct taaagtcatt ttcgataact
   101161 acacattgag ctgaacctcc tggtacttca tgttgttcaa tagcaataac tttacctgat
   101221 actgaagaat gaacgttaca tgaaacaaaa ccttgttgtt cacctatttt ttgcccaaac
   101281 tttacttcat caccaacttc aacaataggt ttagctggtg cccctatatg ttgctgaaga
   101341 ggaatgtaaa ctatctttgg agcttgagct ttttcaagtg cctttgtgtt agagtactct
   101401 tttctatatg gaggatgtat ccctccctta aaagttaaga gtttcattgt tttaccccct
   101461 tatctataaa aaaacatttt ttctgccttc tataagtata ctatatatat taaaaaatct
   101521 taacaattgt taaaaaaata tccgtatttt tataatttat tttataaatc aacacctcta
   101581 tattaagtca aattgaggaa aaggattgct taattaaaca atccttttca tatagctttc
   101641 taaagtccaa attttctgta ttttatttta tagaatttat aaacatagag tactcctgca
   101701 tggatgataa aagcagactt ttacttacac tatatttttc ttcatttgct gcttttgaag
   101761 ctgtatcaat tttttcattc acattcttta catactctat taaattatct ttaaataaac
   101821 gcatttcaga ataatcaatc ttttcagctt cttttgatat attttgtgat attgcctttc
   101881 tatttgtcaa aatagtatta tatttttcca tatctacatt attttcagca ttcgaccaaa
   101941 aacttgattc ttctttaaag tttgttatta atttatttaa ttctttagat atactctcta
   102001 tataagcgta gttacttgta tactctaaag acaacatagg tgcatctaag tgtgataaaa
   102061 atgcatctgg aaacaccttt cttacactgc ttatctgctt tctaacatca ttttcatcaa
   102121 aagaggaata ggtctgtatt ttttttactc catccttctc cataactgaa aaaggtatgt
   102181 cattattaac taatgatgtc tgtatttttt tcaaatcatc attattatct attgcagcaa
   102241 cttgaatagt atacatatcc cagccttcta tagtagctaa tttgacttct tctggctctt
   102301 tagtgttatt taccgctttt tctggattag tttcttgttt atcatctgaa ttggtttgtg
   102361 atttagattt tttccctttt tttattgaat ttaattcatc agatatatct ttataagtta
   102421 tatctgatga attatttaga aatggtattt tagccgatac atactccaat atcttgctat
   102481 cttttatttt tgtataagaa taatagccaa ttagacacaa gcaagcaatc gttataacat
   102541 atttacgtaa atcaatctta tgtctattat tattaaatcc tctgtatatc gtttttcttc
   102601 tattcattag tttgtccctc ccaaaattat attattaata aagtatattt ttaagagtca
   102661 caatttatga atataaataa ttatttcttc taatttttta ataagaaatt gtacttacta
   102721 aacaaatctt cttgcaccaa gtaatacttt agaccaatat gaactagtta aattatccac
   102781 tttaacctta ttaggattag tctgagtacc actacaatgg ataaatttac tatttcctac
   102841 gtatatacct acatgattag ttgttccatc accatcagtg tcaaaataaa ctaaatctcc
   102901 tggtgcataa tttcccatag aaattgcact tccaaaatta gcctgttctc tagaaactct
   102961 aggaatagaa acgcctacag aatgtttaaa aacatactgt gtaaatccag aacagtcaaa
   103021 tttatcaggt cctgaagctc cccattgata tggtattcca ataagagtat atgcaaaatc
   103081 tacgattgtt gaaccttttg ctgtagattt atctgaattt ccagtaaatg atggctttga
   103141 gttactatta gattgagaat tttggttaga tgatgaattt ggtttttctt ttgtatcctc
   103201 attagtctca gaaatataac tggcactcac ccatccaatt gttccactcg ataactttac
   103261 cttataccaa ccattacttt tagcttttaa ttcaacaaca tctccaccat ttaattttcc
   103321 tattatagaa tagcttgtcc caggaccact tcttacattt aaactcacag cagatgttac
   103381 cttaccattc ttgccttcaa ttgattcttc gctagatggt tttttatcag aattattagt
   103441 actatttgaa ttactagaat tgttcgttcc aacatcttct gatgttttag aaatatattg
   103501 gctactagcc catccagtaa ctccatttga tagttttatt ttataccatc cattgctttg
   103561 ttctagtaac tttactacat ctccattatt tgctttacca actaatgaat agttagtacc
   103621 tgcaccactt cttacattca gtctagaact cacatttact ttaccatttc cactaatagt
   103681 tgtcccactt gaagttggat tattttgact tgatgtacct tcagacgaac cacttgttga
   103741 tatgtatttt gcacttcccc atccaacaac agaactcgat acccttactt tataccatcc
   103801 attagacttt tctaaaatct ctacagtttt tcccttgtat aattttgcta ccttatcgca
   103861 atcagaactt ggtccacttc ttatattcaa ggcacttgct gttactgttc ccttttcaag
   103921 agcacttgca tttatggagc taacagatac tgctactgcc ccaattccta aagctgctat
   103981 agcttttttc actactatca ctccccccaa caaattttta tagtcataaa ttcataacat
   104041 tattatccat ttttagtccc tacaatttaa tgataactta ttttcttatt aattgtaaag
   104101 aaattataaa catatcctta aaattagtga tttttaggaa gtatttcaat ccaataatta
   104161 tctgggtccg ctataaaata aattcccata ctttcatttt caaaacatat gcaatctaaa
   104221 tctttatgaa gtttttttgc ctcatcaaac tcctcaactt ctaaagccag atgaaattca
   104281 ttgtctccta aattatatgg tctatcccaa tctctaagcc aagttaattc taatgtatga
   104341 ctagtaatgc catctcctaa ataaactaat ataaaacttc catcttctgc ttccttgcgc
   104401 tttacctctt taagccctaa agctttttta taaaaatcta aacttttttc taaattagta
   104461 acattgaaat tgttatgaca aaaattaaac ttcattttga aatcactctc caatttttat
   104521 tttttttata ttatatcatt attataaatt tatttaaatc atattaagtt aaaaatttga
   104581 atgatgatga ccaattacca aatcatggta aattatttaa aagaatatgt caaaaaaaga
   104641 ataagctctt tcaaatgcat aaaaaattta tacccaagtt atacttaatc atgcaaattg
   104701 gcagaactta ttctttaaaa ctctaacttt taagtttttc tttaataata taatttatta
   104761 ctttttttct aatatcttca gcattataat catcttctac ttctatatcc aaaagttttg
   104821 ctattgacct catatcttct ctagtctttg acctatagct tgatattaat tcatctttta
   104881 ttttctctgg ttctaaaaga tattcttcat ctcctctttt gaaaacaacg tatttttgag
   104941 catatgaact tctattgtag tatatatatc ttgatatttt tcttaaaatt tgattatatg
   105001 aaagtcgctt gttaatatca agttttaagt actctgaaaa agcaaatagc tctttttttg
   105061 atttaaataa tgcttctttc tttatagttc ttgatattga agttacactt tcttgatatg
   105121 cacacttttt taacattttt aaatatactc tattaagacc aatactttga ttgaattttt
   105181 ttatattatt attaataatc ttatccaagt taccttcaaa gtattttttt gctccttttt
   105241 gtgatacata actctcaagt tctttgtggg ccatatcaag tatcattttt tttaaatcct
   105301 ctttatatcc cctagattcc atgatactcc ctcccttagc tatttatagt atattcaaaa
   105361 agctcaagaa atgtgagtca ttacaaaatt tttttacttt ttatgtatat attaatttaa
   105421 aaggggagat aatagtaatg taaaatcaaa catactcaat ctcccccatt tttagacctc
   105481 tattactccc ccaatagagg tcttttttta gtttatcaat ttctattcaa ttccctttag
   105541 ttcaaatcct aattctgcta tcacttcttt taatttttca atagatacat catctttcat
   105601 atctacagat gcacacttat tttctaaatc tacatctaaa acttcaatac catctatatc
   105661 ttctgttaat gcagttttaa gatggtttac acaatgacca caactcatac cttctactaa
   105721 tagtttcttc ttcatttaat tacctcctta taccctataa gggtattcta tcatatagtt
   105781 tatacttttt aaatagaaat taatcattta atttgattca ttcgatttta tatctaaatt
   105841 agatattccc tcatatacat caaaatcatt tggagtaatt ttacctttta atctactatt
   105901 acttacaata tagttgtttc tcacagctaa acttataaat gttgcattat cttttatata
   105961 tgtctgtaca tctttgtatg ctttttttgt ttcaatttca gacgtagaac ttgtaagtgc
   106021 agacatatat ccatttaact tatcatcagt atatccacta ctcgctataa tactacttgc
   106081 atctggtata attgatagtt tccatccaac taatgctaaa tcataatttt tagaattaag
   106141 agcattttcc atatccttat ctgacagctg atttactgta ctatttattc ctatagcttt
   106201 taagttttca tttattatgt ttgcagtttt tattctctca ctattatctc tgtttactat
   106261 tatctttaag ttcatttcag aaagactttt ctttacttcc tctttttctc tatttttttt
   106321 ctcttcagct tcttttttga ttctatcttc ttctgctttt ttagcttttg cttcttcttc
   106381 tggcgtaagc ttctttgagt tctttttagc tgattttttc tgatttttta ctttattgtc
   106441 attttgattt actgagttta catttgcata ttctacctta gcaagacact ctatcgcctt
   106501 atctttatta aactctaaat ccttcatttc actattatag tattttgatt ttgaattaag
   106561 tggaaaatta actggagtag catcatccat ataaccttca ctaataattc tatctttatc
   106621 tatagagtgt gcaattgctt ttctaaaatt aacatctttg aaaaaaggat tattataatt
   106681 aaataataca cactcataat ctcttccttg atattttgtt atattaaact ctttttcttg
   106741 aaacttactt aaatcattta atgtaacatt ggttatatca ctatcaagag ccataaccat
   106801 agatgtcctt gcatcttcat taggcaccat acctactttt atgttcttca tggtttttgg
   106861 aacttcttca tagtaatctt tgtttacaga taaaaccatt ccttctcttt ctgtatatga
   106921 ttctatttta tatttcccat ttcctatcat attattattc ttgtcattta catcttttga
   106981 atctaaatga ttttgagata caattggaaa aattaaacta tcaattgaaa aagcatatct
   107041 agctttaaat tttattgtaa aatctttatc tgatttaata ttcacagaag ctatattttt
   107101 agtaaattca ttatatggac tatctgcact tttttgaatt aaaccaatag tatagtttac
   107161 atcatttgaa gtaatatttt ttccatcatg ccactttgca tcttttagct ttatatctat
   107221 actcattcca tcctgagcta tattatactc cttaactaat tgaggaatta cattgtagtt
   107281 ctcatctata gtaaataaac tatcataaac taaattcatt atataaccaa cagacttatc
   107341 agtattagtt ataggattta tagtttttgg agttaccatt gttaagttta tatacttagc
   107401 atctatagaa ctttgacttt gtaaacttga atcactacta ctttgttttg ttttagtatt
   107461 actacaacca gctaccataa gagttatagc taaaacgact gttaagactt ttattctctt
   107521 cattagtttt ttcctttctt gccatatatc ttattataat gttcgtaatt attttttact
   107581 ttttctacat attttgaagt ttgcttaaaa ggtatatcat gtagattttc gccatcttta
   107641 ctatattcat tattttctaa ccattttttc acattacctg aaccaccatt atatgcagct
   107701 atcactaaat ctaatttacc aaattctttg tataacttac ttaaatacca acagccaagt
   107761 cttatattag tctctgggtc gaaaatatcc acatttttta aatttagttc ctctgctccc
   107821 caatctctag ttatgtctaa tatttgcatt aatccttttg cttccttttt tgaaacagca
   107881 gaactattaa acttactttc ggctttaata acactgtaaa ctatattttc atctaaatta
   107941 aattctttcg aatacttttc tacatactct gaatattttt taggatataa aaatttatgt
   108001 attactttgc tttccattaa tagtgcccca aataagatta taaaaataga tagaatcaat
   108061 actttcttac tattcacgcc aattctcctt catgtactca ataaatttat gtgctttact
   108121 ttctaattca gttattgttc ccgaattatc tattatataa tcaccatatt tggatttttc
   108181 ttcctgactc atctgtgaat ttatcctact aagtgcttcc tgctcactgc aattatctct
   108241 cttttgtatt ctactaattt gtacttcttg tttacaagta actactaata gcttgtcaac
   108301 catatctaaa aaaccacttt ctaccaatat tgccgcatct aacactacta tattttcgcc
   108361 tttttttctc aatttttcta tttcacttat tattttttct cttattcgtg gatgagtcaa
   108421 gttatttaat tccttaagtt tttcttcatc actaaaaact attttcccaa gagcttttct
   108481 atttagagtt ccatcatcat tttttatact ttgcccaaaa tggacaaata ctttttccaa
   108541 taacaactta tcctcaaata tcttcctgga tataatatca gcatccacta taggaatgtt
   108601 aagatttcta aatatatttg ataggctgct ttttccacag cctattcctc ctgtaagtcc
   108661 taatatcaac ataaaatcac ctactttgtc tcataccaag aactacctac atttaaatct
   108721 acatctaagt gaacatccat atttacagca ttttccattt cttcttttac tattttctta
   108781 actatatcta tttcatcatc aattgcttca actatcaact cgtcgtgaac ttgtagtata
   108841 agttttgatt tcaaattgtt ctcttccaat tttttatgaa catttatcat agcaattttt
   108901 attatatctg ctgcacttcc ttgtattggt gcattcattg caaatctctt tcctctattt
   108961 ctttccataa aattgcttga ctttatttct ggtatatatc ttcttctgtt taaaattgtt
   109021 acagcatatc catcctcact agccttttct actgttgtgt ccataaactc ttttatttta
   109081 tggtatttag caaaataact ttcgatatat tctttcgcct ttggaacagg tatatttaaa
   109141 tcatcagcta gaccaaagtc acttttacca tatataatac caaagtttac agctttagct
   109201 gcacctctca attcactagt aacatcttcc ataggaacat taaaaacttg tgaagctgtt
   109261 ttggtatgaa tatcttcatg atgtttaaat gcttctatca tattttcatc ctgactcata
   109321 tgtgcaagaa ctcttagctc tacttgtgag taatcggcat caaccaactt acagttatca
   109381 tctgcaataa acacttttct tatttttcta cccatttcca tttttatagg tatattttga
   109441 agatttggtt ctgtagatga aattcttcct gtagtcgtta tagtttgatt aaatgatgaa
   109501 tgtattctat tactttctgg atttattata tttaaaagtc cttcaacgta agtagaattt
   109561 aactttacta tttgtctata ctcagttatc ttatctatta ttggatgctt atctcttaat
   109621 ttttctaaaa catctgcatt agttgaatat ccagttttag tttttttaat tattggaagc
   109681 tctaattttt caaataatat aacacccaat tgttttggtg aatttatatt gaatggctct
   109741 cctgataatt cataaatttc cttttctaat gtagctatta tttctttaaa ttcaacactc
   109801 aattcatcca atatactttt gtctactttt ataccttcat actccatatg acctaagact
   109861 tctactaaag gcatctctac atgataaaaa agaccatcca tactcatatc cattagactt
   109921 ctttccatca taggaactgt ttctttaact gtgcatatta tttgacccat atactctgct
   109981 aaatcctcaa attctaaatc ctcatagttt ttagatttaa caccctttcc taataattct
   110041 tcttttgatt taaccttttt tgataaatac ttcatagcta ttgcactaca atcatatgag
   110101 gtagatgaag ttgaatctat taagtactca gctattgtta tatcaaaata catattttct
   110161 aagtttatat tatatggttt taaagatata taatcatctt ttaaattata tccatacttt
   110221 ttaatttcat tatttgaaaa tatactatct aactttgaca cttcatttga atctacataa
   110281 tatatttttt ctccatctac acttataaaa atatatatta tatttttttc aagtatatta
   110341 ccttgtcctc taacagtttt taaaataact tgtccttttt tgtttacttc atctataaat
   110401 ttttctatat cttttaattt taatatttct attttttctt ctacgtgttc tgtgtcatct
   110461 gaatcgacca aatcaactaa tcttgataag agacttgtaa atccaaagta tctaaattta
   110521 tctaaaagtt catctttatc ataatcgcca aaaatcatac tatctaaatc cacttctatt
   110581 ggcacatctc ttataattgt tgcaagtctt ttactttgaa tagctatttc tttgttttcc
   110641 tctattttct tttttacact acctttaagc ttatctgtat tctctattag attctctata
   110701 ctagaaaact cttttataag ctttatacct gttttttcac ctattccagg tactccaggt
   110761 atattatcag acttgtctcc cataagaccc tttaaatcga taaattgtgt tggagtcatc
   110821 tcatattttt caattacaga attaaagttg tattcttcta cttctccaac cccttttttc
   110881 gttataaggg tagttgtatt atctgaagca agttgaatag catctttatc tccagttact
   110941 atgtatacct tatatccatt ttcttctgct tttttagaaa cagtacctat aatatcatct
   111001 gcctcataac catctatttc tagtctattt attctaaatt tatctaaaag gtcttttaat
   111061 ggctgtaatt gttctgccaa ttcatctggc ataccctttc ttccagcctt ataatcttta
   111121 tattctaaat gcctaaatgt aggtgctttt ctgtcaaaag ctacacttat atgtgttggt
   111181 ttatatatat ctatcatttt aaatagcatt gtagtaaacc catatatagc attggtcttt
   111241 aacccttctt tattattcat ttctggaaga gcataaaaag ctctatttat tattgaattt
   111301 ccatctatta taattaattt tttttccaaa ttatatcact cctaaaaatt atctattttt
   111361 gtaacatata tattatatac caatatagtg ttatttaata ttcccataat aataatagta
   111421 tattaaaatt aaatatgttg caaacaatat atttttttgc tataataata tacatgacat
   111481 gcccgagtgg tggaattggt agacgcagtg gactcaaaat ccaccggact aatactccgt
   111541 gccggttcga gtccggcctc gggcaccatt aaaaactcct aaagctattt attcaataga
   111601 ttaggagttt ttttattttt gatttaaatt ttaagttatt ttttgaaatt actgtgtctt
   111661 tttaaaattt atataattat ataaatttat cttctagcat taatttaaaa actaatttac
   111721 ttttatataa ttttctattt tatatcataa cttattacaa ccttttatct aatttattgt
   111781 atacaacaac actacaaata aattgaaata aaataagcaa tccaagaaca actaaaaccc
   111841 acttgcttat taccattaca gaaaatacac tcaatataga aacaataaat ataagaatta
   111901 caagaacata gcacatgatt tgattagtaa tacgtccagc tttatcacgt aacataattc
   111961 ttctttcatc attcatctct atcctttgat tttttatctt ttcttcataa tctactgctc
   112021 tttcaggttt actccaatac atatattgaa gaatcataca tacacctgga cctaaagcag
   112081 ctccagataa tccccaaata aaagcctcaa atgaaaactc agtaaatgta gccaataaaa
   112141 caagtaaaat tccacaaata aaatatataa ttccaacata taacatattc tttttcattt
   112201 ttactcctcc tcataaataa atatttcttc aatactcata tcaaagtatc tagctatctt
   112261 aaaggctaag atgatagaag gattatacct accattttct aatgaaccta tagtttgtct
   112321 tgatacttgc aaaatagaag caagttcttc ttgttttatg cctctttctt ttcttatttc
   112381 ttctaatcta tttttcacat ctatccccct ttaatatctc aactacggaa agtctacttt
   112441 ccataattat acaactatat tccatttatg taaagcttac tttccatatt tacaaaaaaa
   112501 taacagacta ttttcagcct gtaattttag aatttcatgt tgtttattaa ttttaatgtt
   112561 atttattaat tccatattat ttattaattt taacttggtt tctgaattgg aatccaaact
   112621 tctgtagtat aatcaggagc attgatatcg ccattgggat aaagttcaat atctggtaaa
   112681 ttagcataca catacccaga acttggtaac cactcagtaa taattctttt ttgcaattcc
   112741 tgtattgcca gagcatttgg cattggagaa acacattcaa atactgccca tgtgcctgat
   112801 ggtattaagt attcatgagt atcttctaat acaggcttat ctgttggagc agcaatataa
   112861 taatctaaac ccttactatt tgtacacaca ctaactccaa gcaatccaca aggttcatta
   112921 tttattaact ctgaaagttt atcaattgtt ccatttttta tgcatttagc ccacaactta
   112981 ggaactttct caaagcactc ttctacaatc atgttcatac tttcttttat accaacaata
   113041 cgaaaccctt tcttttctac aatacgatat tgcatttcta tatttccttt tacataaatg
   113101 cttaatgtca tcttaggata tgcttttaaa acaacaccct ttgctctagc tgcagatgga
   113161 gaaatgttat gtatattttg aaaagctcta ttaaaagatg ttggtgaatc gtaaccatac
   113221 ttctcagata gttctaaaat tttgatgtta ctgttctgaa gttcaaatgc agccttagtc
   113281 atacgtcttc gtctaatata ttcagataat ggtacttctg caatatatga aaacattctt
   113341 tgaaaatgaa aggttgaaca acatgcaatt tttgctgctt ctgcataatc cactccactt
   113401 tcgagatttt cttcaatata agtaatagct tgatttaatt tatttatcca ttccatttga
   113461 tattacctcc aagcaaatta tacagtttaa taaaataata tacctctcta ttcatgcaca
   113521 aaattgtaag catttaaatt tataagcatt tttcaatcaa tacaataaat ataaaaattg
   113581 tattatacaa taaaaaagtt caataacatt atattgtaaa atgttattga actttttata
   113641 aaaattaatt taagtgtagt taaattaagt attacactat cttatatatt acaatatcct
   113701 actatcttat agtcttctgg cactttataa tctttgtctg gagtacctaa attccatttt
   113761 aaatcaaaca tagttgcact tattattgtt gcaaaataaa gcataactat accaatgtct
   113821 attttttctt catataaatt agtatgacca tcttttctaa cagctaaaac tacagtgcct
   113881 ccatcaacta taaatctcca tggttgtcta tttaatgtag atggagctaa tcttgcatag
   113941 tgaaatgcat caagaagtgc tctttcttct aagatttcta tacttgcaac atttccccat
   114001 tcgttcatat aaacaacatc ttctacacct agtctagtag accccttatc tgttacaact
   114061 tgcatatcag attttgaata attttgccca gtttttgtag catttaatac tttagcatta
   114121 cttacatttt ctccatatcc aatagctata attcctgtta cctctttatc tgaattaatt
   114181 ccaagttttt cttttacctt ttttccatct tcaaaagtaa cccaacaaga accaattcca
   114241 agttctgtta ctttaaagat tatactttct cctatgtacc ctgaattttc aatgtaatta
   114301 tcttttatgt cagataatat tataatataa cttggagaat ctatcatatt tcctttgtac
   114361 cctgctactt tatctaaatt attaaaaact tcacttctat tcataattct tacatcaaca
   114421 tctatttctg gaactagttt cttacaagat tctgagtatt tcttaatttc actaagatat
   114481 tcttctttaa tatctgtgtt cttatattct ctaacagact ttctatttaa tatgattgtt
   114541 ttataatcca taattttatc ctccccaaac tagtattgtc ttaattatat acccattaat
   114601 atattatttt actcatttat ttaataaata aagattacaa ttttgtaatt attatttatt
   114661 aataatattc cacttttaca ttaataatga ccagttgtgc aaaatccatt gccaaccacc
   114721 aaataaaaac atattataaa ggtaatataa aataacaaac aaatcttaac aaaaaattaa
   114781 acttttttta cacgaaagaa ggcttcccgt tgccttcttt atttttataa aaaaataagc
   114841 tgtttctaaa atgatttcac atttttgaaa cagccaagtt attctataat gacaactata
   114901 atttgaggat gtgagggaga gttgtcatta taaatttagg gtaattatat tatgttttaa
   114961 gctagttctt tctatattta tataatacat tttatatatg aattttatat gagattggta
   115021 taaatgatat atgaaattac atatgtttat attatattaa attttattat tacattttcc
   115081 acaacaatac tcatatgtct ccacattatt tggaatattt acaaatacaa attctttaca
   115141 gttctcacaa tactttaata tagatatagt tccacaagtg taacattcaa atattacaca
   115201 atcctcattt tcctctacta tttcaaactt tttactatgt tcaccacact ctgggcactt
   115261 gtgattattt acattcataa atactcctcc ttattagtat agttacatgt caaaaactta
   115321 attaatgtat tctatattac ttattatata ttctataata aatcatattc taatataata
   115381 aaacaaatta aataaaaaaa aaaccataaa ttttaaattt atggattaat tcttgtaatg
   115441 ataactctat ttgaggatgt gagggagggt tatcattaca atagggtatt atattatggt
   115501 ttttaagcta gtctttctac acctcatatg atacatatgc tatatgaatt ttatatgatt
   115561 tttacataaa tattttatga aatttaaatt ttttagtcat tttgaaattt gtaaaaagtt
   115621 ctctaaaaat ccacagcatc ataaacagcc aaaatttaag taaaacatca taaaaaaatt
   115681 tgtccaataa ttttaacaag taatctcacc tcattataat tattgacaca aacttaaata
   115741 aacaatctat aaatcttcta taaatcttaa actttccccc tattgataca caatttctag
   115801 tttgtcaatt ttattttgca tttctaagaa aatttcttca acagaattgt taaatatatt
   115861 gcctaaatag attcttttat ctttttgaaa tgaataagat tttacactac catcagaaga
   115921 aatatataaa tgactccact ctgctccata ttttgaaaac ctctcctttg tatctttaaa
   115981 cctcatatct tctattttta ttgctttttc tctgtctcct cttactacag tgtgacccct
   116041 ttttattaaa ctggttattt ttatatcttc ttttaattta atacgtgtat catcattttt
   116101 tgaatatact ttccatatca ctttatgacg ataattatct aattccttta ttaagcttct
   116161 atcaatagta aaactatctt tagttaccac aattaaatca aaatggtcta acatatattg
   116221 aaatatttct ctcatacttt tattttttaa aatatcctca ccaataacct ctataaatct
   116281 acagcctttc tcatacatgc agttcaataa acttgtgatt tcagaaaaat aatcatttgt
   116341 attattatct ccatctattt ctatagtaaa gtacaaagga gtaatgtatg atttatttcc
   116401 tgttatctca aatacacttg atagtgtctg tatatcatct tcaaacgtta agtacacatt
   116461 ctcataaaac ataaaaaatt ccataacttt ttctttcata ttatggatat ttctatatct
   116521 attggataat atatttatta tatcgtcagt agtatttttc ccatcacatt cagccagtat
   116581 aacaatttgc ttccaactta agctatccac atttccgata ctttttttat atccatcttc
   116641 ttcgtcataa ataggaccaa ttataatgtt ttcttttggc cacagatgaa ccctagttcc
   116701 atcttttaat ttcggatatt tattttttac agactcataa aatctacttg tatcacccat
   116761 gattctttac taccccccat agtttaaata ttctatgcta aaaatagcac tttattttta
   116821 ttaattcaac aattattcaa aattggtcat tatatatgtt taaatggatt taacatcaac
   116881 cttatttata tgttattgat gtttatatat gttatataaa atcttatttc tcatacttaa
   116941 atgtaatctt aactatctct ggtttacaat taagcctaat taaaactttt gagcctccta
   117001 agcctttatt taaaatcata gtgctattat ctttttcata ttttccccag tcatacttag
   117061 gaaagaactc tctatttgga gataatacac ctccaacaaa aggtattctt attatacctc
   117121 catgaacatg tcctgctaaa accaaatctg ctccccattt tgcatatttt tcaaagaaaa
   117181 atggtgtatg tgctaaaaga atgttatatt cattttcatt aactttacct agattgtctt
   117241 ctacaaaatt gtcacttagt tctaattttt tgttattagc aaataaatat ggatagcatt
   117301 ccaatggtat aattaaacca tataaattaa gatggctatt acctctatat attcttacag
   117361 attcattttc catatttatt attttctttg aatatagttc cttaaaataa tccttatata
   117421 gatgtttata cttttttatt aaagattttt gttcatgatt tccaattata tgatatactt
   117481 catatttttc aaccaaatta tctattaaat ctaatgcaac ttgaaaattt ttattttctc
   117541 catctactaa atctcctgtt ataaatataa catctgggtt taatgattca attttatcta
   117601 tcaatacctt attattttta tcaaacacct tattatgtaa atcactcact tgaactattt
   117661 taaagttatc aaattccttt ggaatttttt tgttgaaaat agtatattct gtcgtttcta
   117721 tatgctgagt ttcatactta tacagaatat acaataatat taatactaat actgtcattg
   117781 aaacctttat aatcatattc tcttcctctt tattctattt tgttaatatt attataatgc
   117841 ttttatgttt tttttaaaac aataacatca tcacatacat ataaatcttt tcgacattat
   117901 aaaaataagt tatccttttc taaaattttc atttatttta gaaaaggata actataaaat
   117961 tatctataaa cctctatatt gtgaaatata gtttttcctt tatttaaatt tttatatata
   118021 tgctctaaag ttccatcaaa cctaatagaa tgtccagact ctaaaatata agttttccca
   118081 tccacattaa ggtcaagttt accttctatt acgagcacat attcttctaa aacatgacta
   118141 tgtgtagatg aaacatgagt acagttttcc tcaagctcaa ttataaaaag ttcaaacctt
   118201 ctttgagggc taaaagggta tattggatat aacttcatgt tccctttttg ctcaacaata
   118261 ggctctactt cttctttctt tataacctca taggtatttg tattttcatt taatagtgta
   118321 gtaaaattta ttttaaatcc agatgaaatt ttccataaag tagatactgt cggacttgat
   118381 tcacctctct caatctgtcc aagcattgct ttactgacac ctgtcatctt tgaagctttg
   118441 tctaaactta tgcccatttc ttgtctcaat aaccttaaat tttctcccac attaggaaat
   118501 ttattatcca tgttaaaatc ctcctgatag ctatttgtat tctatgattt ttactcctgt
   118561 aagttctact atctctttta attttaacat atgattgtta caaatatcat caaattcata
   118621 tatataatct tcaagcccta atgccttata tttatcgatt ccaaatttat gatatggaag
   118681 taactccatc ttgcctcctg gaacattttg tttgacaaat aatgcagtat ttcttatatt
   118741 ttcttcacta tcatttactc cataaataat tggcactctt ataaccatag atttattcaa
   118801 ctttgaaagc ctacatatat tatctaatat aattttatta cttactcctg tatattcttt
   118861 atgaatatta tcatccatag attttatatc tacaaatatg tggtctattt tctcaaatac
   118921 atcatttacc ttattccaat caaaatatcc acaagtttca attgcaatat ttatgccttt
   118981 atcataaaaa atatcaacta attctcttaa aaaatcaatc tgaagtgtag gttcacctcc
   119041 agaaaaagtt atccctccat tagattcaaa gaaaaatata aaatcttttt caacttcctc
   119101 tactatttct tcaacactca tttcttcggt cattatacaa atggcatctt taagacatac
   119161 cttgatacac tctccacata aatcacattt attatttatt tgcgctctat caaatagtga
   119221 acttatattt tgaggacaaa catctataca tctattacag gatacacatt tatctttcat
   119281 aacacctaat tttactatgt tactccagga atctggatta gaacaccact tacattttaa
   119341 tttacatcct tctaaaaata tagtagtcct tattccatct ccatcattta ctgaaaaatg
   119401 ttgtactttt acaactctac cttttttact cataatctac ctcataatta aaaattgcta
   119461 tgtgaatttc tagctattat agcatcttgc atttctcttg ataaattaac aaattgagta
   119521 ctatatccag caaccctcac taataaatct ttatattctt ctggattttc ttgagctttt
   119581 aatagagtat catttgatat cgtattaaat tgtacatgga atcctcctaa agcaaaatat
   119641 gatttaatca tagatgttag atttctaagt cctctttcag tttccaccaa atcttgattc
   119701 agtcttaaat ttagaagtgt tccaccagta tgaacatcat gatttatttt tgatgcagat
   119761 ttcattgctg ctagtggact tgttgtatca gtaccaacaa atggagaaac tccctctgtc
   119821 aaaggttttg tcgcttttct tccacaagga gttgcaccta ctatttttcc agttggtaca
   119881 tagtttgata tacccataaa tgcactatta aatttagagc caaaaatatc cttgtatttt
   119941 ctagtttcag tataataaaa atcagaaact tcaattgcta atgaatctac ataatcatta
   120001 tcatttccat acttaggaac atccaacgca agttttctta attcttcata accttcccaa
   120061 tcattattta gtgcttttgt taattcttct aacgtagtca ccttatcctc aaatactaat
   120121 ttttttatag ctgccaatga atttgaaact acacctaacc ctataccagt taatacagga
   120181 cctatattat attttgctcc tcctttactt aaatcaactc ccttatccaa acatccatct
   120241 acacaagtag ataaaaatgg tcttggtacc atttctttat gaatttgttg agcaacagta
   120301 gttcctataa cagaactttt tacaagatat gctaattgct ttaaaaactc atccttaagt
   120361 tcttcaaaag aagtaaattc tgtgatattt tttgtatcta accccatttt ttctccagtt
   120421 aatctactct taccttcatt catagcatat tctaaagctg ctgcaaaatt gatatttacg
   120481 gctgaagtcc actgtcctgt ttttctaaaa tgaggaacta cacaaccaca gttactccaa
   120541 tctctagcat cttctgcatc atatccatct tgtaataaca tttgtgcccc tgcactatcg
   120601 ctgtgtatag cagggaaacc agttccttgt tttaccaatt tagcaactgc cattacgaaa
   120661 ttatctggtg ctccttgact cactctaaca cttaatcctg gttggtgagt ttttacactt
   120721 tctgtagcct ttaaacacat atatgagata tcattcgttc catcagtacc atttctcttt
   120781 ttaccaccaa cagtaagatt ttggaattga ttatatcctg caaagtaatt tgctgtattt
   120841 gctgatatag tccataccca ttctgataac ttaatccaaa gtgcttctat caattcttga
   120901 gcttctgatt cagttatttt accttctcta gcatcatttt cataatatgg atacatatat
   120961 tggtcaaatc tacctaaatt taatgccaat ggattttctg atagaatacc acctaattga
   121021 acaaaccata caaattgtat tgcttcataa aaattagttg gagggtttgc tggtacattc
   121081 atacatatct ctgaaatttt tataagttct aactttctct tttcatctgt ttcttgctta
   121141 ctcatctctt ttgcaagatt tgaatatctt tgtgccaatg tcataatacc ctgtgcaact
   121201 atagaaacag atttgtaaaa atctatcttt tcaatatttt ctgaaactga tatatctaat
   121261 tctttaattt ttttatctgc atcttcctta atccctttat atccttttac aaacaatata
   121321 tcttgataat ctggtgttac ttcaccaact gcctgtctcc acttagaatc attatctatt
   121381 attcctgtat ctactaatat cttagctgta tcttctggga ttcttgctaa gaaaacttct
   121441 tccaaagatt ttcccttcca atatggaaat atttcttttc ttataaattc tatttgttct
   121501 tttgatatta catatgggtc ttgagttctt ttatcaaaag tatccatttc tttgtctacc
   121561 cattgccaag aaaactctgg tgtcaatatc cctgttcttc taaattttcc tgctgtacct
   121621 actattaatt cattttcaaa gatttttata ggaagttctt tacatgtctc caaaaaagct
   121681 ttagctcttc ttatacagat agcttctccc tcagtttttt tatgtgattc tgtaaaaatt
   121741 ctagcccttt cacaacatat cataggttta gaattaatat attcttgtct aaatgcttct
   121801 attctattag tttgactcat ttaaaatccc cctttggata atatatacta catttttgta
   121861 tgttataaca tactttaatt atattatact gtcctttagc ataaaatgga agcaaaataa
   121921 cttatttttt ttcatctacc ttgaacacct atatattaat actttttttg ttaaatttat
   121981 aaactctaaa aaaattttct atgatatatt ttctatattg ttatagttat ttctaatata
   122041 ctaatgattt gaaatatcaa atttgtatac tagacttagt tttaaaacct tagttgattg
   122101 tttaactttg ttaacttcaa catgtatatc cttcatataa ggaagctcta caacacctac
   122161 tcccttatta aagtcttctt caaccataga aaaaatttct ttctcagtta agttcgtatt
   122221 agtcaatgac ttaaataaat tgtatataaa tttaatatat ttatcactct cagataactt
   122281 atcatcttct ggatactctt tagcacagag aatatctatt gttacttttc cttctttatc
   122341 gtcttcagac atagaataga ataaacttcg aatatttttt tcaggtggtt tttcagcacc
   122401 atttatagat actacaaagc taccatctga ttttgagtca gtaatactat aaccactgtc
   122461 tattatagct ttcgaaaatc tttgagataa atcttttttt acttcttctc tacctttcgc
   122521 atcattaatc ttttgtgagt aattattaaa aagctcgata gattcatctt ttttatcttc
   122581 aacttgttct ttcaacgaat ctttactaat ttgttctgag ctacttaagt tcttatcata
   122641 tacaggagac atacacccta ccatcaatgc taagctaaga tttaaagcca caatgattgc
   122701 cactctattt atattccttt ttactttcat acacaatcct cccatcacac taaccgctct
   122761 aaagtattac ttattgcact agaatatgtt tatattttct ttatattaaa gatttattat
   122821 tcaatacata tcaccttcct atccaattct tataacttac tattagtaaa attataagct
   122881 ccttaataca gaaataagga tgttatcttt tgttattaaa agataacatc cttatttttt
   122941 tgtatcaata catatgtccc aactggtaac ttaatcgccc caactgtcag tatcttggtc
   123001 caatggtata tatatattta gtataaattt atcgatacta ttttcaaata ataattctcc
   123061 attatatttt tgtaaagaag atttaatact ctgaatacct attccatgta caaacttatc
   123121 cattttgttt gttaacaata tatttttatt aaaagtaagc tgatttagtt tactattttc
   123181 acatttaagt acaaaaaatg accttgtcat agttccttta attctaatat atttattaac
   123241 attttcatcc actattttat cacatgcttc tattgcatta tccaaaatat tagaaaatat
   123301 gcttgacaca tctataggtt ttacaaaatt tacttttgaa aaatttatag agcaagtaaa
   123361 tttaattcct ttttttaaac atatttcact cttttcgttg attataatgt ctaatatcat
   123421 atttcctgta ttatagatat atttaaatgt ttttatttca tcttttaaat tgttaacata
   123481 ttcattaatt tctttgctat tgtttctaag gttgtctata caataaatgt gattatttat
   123541 atcgtgatat agtttcttaa ctcgcatatg agattcttga atacttaaat aatgcgcata
   123601 ttgcatatct aacttatttt ttattaattc agcttgagat tttaatctat tctcttttat
   123661 tatttcttta aacaatagta taagaaatat actactagct cctaccaatt ttggattaac
   123721 aaaattatca aaatagtatc cttctgaatg taatgaccca aaccgttcta atttttttaa
   123781 tacataattt acaagcatat tcattgtatt aactaataag gcaaataata aatatacata
   123841 atttctctta tcttggctaa ttaattttat agacttccta aaaaagctaa atataagata
   123901 tataagaata attattaaat tactatatat ctgaattttt atagattcta agtgaggtac
   123961 taataaggat tctttagatg aaataacatt acctgtaatt gcaaaaaata gtattctata
   124021 tataacagca tccaaacatt tataatatac actaaataga taaaagaaaa tggaatactt
   124081 aatataaccc atcttataaa aataattata gtatcctccc caagcaataa atgctaatat
   124141 ataaaataaa tagtttatat tactaaagta atttcctcca ttaaataatc tacttatctg
   124201 aattataata taaataagaa acaagacaat atagaatact attttttcat tttttttact
   124261 atccttttta taaattaaaa ttccgttcat tatagaaaac tgtataaata tagataaaac
   124321 tactaatagc tcagtcataa agtttagcat attgtatcac caagaaattt taagaatttc
   124381 tccttaactt ctttatatct atatctacta ataggtacct cttctccact ttccagtatt
   124441 gcagtattag gctttatatt ttcaacatat cttaaattta ctataaaact tttatggcat
   124501 cttataaatt tatatggatt taattctttt tctattttgc ctaaactata ttttatatca
   124561 aaattcttgt ttattgtgtg tattagcata tctttttttt gaacttctat atattttatt
   124621 tcatttaaat aaatcttata tgtattagac ttatttttta ttgtaatatg actttcctta
   124681 tttatttcaa tatctttgat acaagttagc acatgttttt ttagttcttc caactctatt
   124741 ggctttagta aatacctata agctcttacc tcataacctt cttgcacata atctattaat
   124801 gaagttacaa atatta
//
LOCUS       DAGQVA010000003       105868 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.003, whole genome shotgun sequence.
ACCESSION   DAGQVA010000003 DAGQVA010000000
VERSION     DAGQVA010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 105868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105868
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.003"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            288..1505
                     /locus_tag="MIV85_000256"
     CDS             288..1505
                     /locus_tag="MIV85_000256"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBY2959634.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1600..1980
                     /locus_tag="MIV85_000257"
     CDS             1600..1980
                     /locus_tag="MIV85_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBY2959635.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2264..2746
                     /locus_tag="MIV85_000258"
     CDS             2264..2746
                     /locus_tag="MIV85_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2959636.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2767..3582
                     /locus_tag="MIV85_000259"
     CDS             2767..3582
                     /locus_tag="MIV85_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2959637.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3635..5185
                     /locus_tag="MIV85_000260"
     CDS             3635..5185
                     /locus_tag="MIV85_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2959638.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGYIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSVIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5282..6634
                     /locus_tag="MIV85_000261"
     CDS             5282..6634
                     /locus_tag="MIV85_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBY2959639.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6765..7523
                     /locus_tag="MIV85_000262"
     CDS             6765..7523
                     /locus_tag="MIV85_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2959640.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLISNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELFNLLHTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7570..8289
                     /locus_tag="MIV85_000263"
     CDS             7570..8289
                     /locus_tag="MIV85_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBY2959641.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8413..9813)
                     /locus_tag="MIV85_000264"
     CDS             complement(8413..9813)
                     /locus_tag="MIV85_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBY2959642.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9817..10725)
                     /locus_tag="MIV85_000265"
     CDS             complement(9817..10725)
                     /locus_tag="MIV85_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2959643.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPASEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKMIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10986..11633
                     /locus_tag="MIV85_000266"
     CDS             10986..11633
                     /locus_tag="MIV85_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBY2959644.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11957..14596
                     /locus_tag="MIV85_000267"
     CDS             11957..14596
                     /locus_tag="MIV85_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBY2959645.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14654..15757)
                     /locus_tag="MIV85_000268"
     CDS             complement(14654..15757)
                     /locus_tag="MIV85_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBY2959646.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIHLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16118..16939
                     /locus_tag="MIV85_000269"
     CDS             16118..16939
                     /locus_tag="MIV85_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBY2959647.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    17018..17229
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17316..18632
                     /gene="argH"
                     /locus_tag="MIV85_000270"
     CDS             17316..18632
                     /gene="argH"
                     /locus_tag="MIV85_000270"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBY2959648.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18881..19219
                     /locus_tag="MIV85_000271"
     CDS             18881..19219
                     /locus_tag="MIV85_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBY2959649.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19346..20635)
                     /locus_tag="MIV85_000272"
     CDS             complement(19346..20635)
                     /locus_tag="MIV85_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBY2959650.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20715..21419
                     /locus_tag="MIV85_000273"
     CDS             20715..21419
                     /locus_tag="MIV85_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBY2959651.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQRNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21511..22557
                     /gene="selD"
                     /locus_tag="MIV85_000274"
     CDS             21511..22557
                     /gene="selD"
                     /locus_tag="MIV85_000274"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21559..21561,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBY2959652.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22575..23987
                     /locus_tag="MIV85_000275"
     CDS             22575..23987
                     /locus_tag="MIV85_000275"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBY2959653.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            24101..25984
                     /gene="selB"
                     /locus_tag="MIV85_000276"
     CDS             24101..25984
                     /gene="selB"
                     /locus_tag="MIV85_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBY2959654.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26089..28827
                     /locus_tag="MIV85_000277"
     CDS             26089..28827
                     /locus_tag="MIV85_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBY2959655.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28946..29890)
                     /gene="manA"
                     /locus_tag="MIV85_000278"
     CDS             complement(28946..29890)
                     /gene="manA"
                     /locus_tag="MIV85_000278"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBY2959656.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            30063..31424
                     /locus_tag="MIV85_000279"
     CDS             30063..31424
                     /locus_tag="MIV85_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2959657.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31512..33401
                     /locus_tag="MIV85_000280"
     CDS             31512..33401
                     /locus_tag="MIV85_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2959658.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISTVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33416..33871
                     /locus_tag="MIV85_000281"
     CDS             33416..33871
                     /locus_tag="MIV85_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2959659.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33930..34247
                     /locus_tag="MIV85_000282"
     CDS             33930..34247
                     /locus_tag="MIV85_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBY2959660.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34272..35534
                     /locus_tag="MIV85_000283"
     CDS             34272..35534
                     /locus_tag="MIV85_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBY2959661.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35639..36703
                     /locus_tag="MIV85_000284"
     CDS             35639..36703
                     /locus_tag="MIV85_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBY2959662.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36757..37935
                     /locus_tag="MIV85_000285"
     CDS             36757..37935
                     /locus_tag="MIV85_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBY2959663.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38126..39184)
                     /locus_tag="MIV85_000286"
     CDS             complement(38126..39184)
                     /locus_tag="MIV85_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBY2959664.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSKIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39251..39622
                     /locus_tag="MIV85_000287"
     CDS             39251..39622
                     /locus_tag="MIV85_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBY2959665.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIESRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39659..40333
                     /locus_tag="MIV85_000288"
     CDS             39659..40333
                     /locus_tag="MIV85_000288"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBY2959666.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40582..41421
                     /locus_tag="MIV85_000289"
     CDS             40582..41421
                     /locus_tag="MIV85_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBY2959667.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41665..41761
                     /locus_tag="MIV85_000290"
     tRNA            41665..41761
                     /locus_tag="MIV85_000290"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41699..41701,aa:Sec,seq:tca)
     gene            41916..42623
                     /locus_tag="MIV85_000291"
     CDS             41916..42623
                     /locus_tag="MIV85_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBY2959668.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42765..43601)
                     /locus_tag="MIV85_000292"
     CDS             complement(42765..43601)
                     /locus_tag="MIV85_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2959669.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSKAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43789..44694
                     /locus_tag="MIV85_000293"
     CDS             43789..44694
                     /locus_tag="MIV85_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBY2959670.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44703..45887
                     /locus_tag="MIV85_000294"
     CDS             44703..45887
                     /locus_tag="MIV85_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2959671.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            46002..47303
                     /locus_tag="MIV85_000295"
     CDS             46002..47303
                     /locus_tag="MIV85_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBY2959672.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47257..48300
                     /gene="holA"
                     /locus_tag="MIV85_000296"
     CDS             47257..48300
                     /gene="holA"
                     /locus_tag="MIV85_000296"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBY2959673.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48487..48753)
                     /gene="rpsT"
                     /locus_tag="MIV85_000297"
     CDS             complement(48487..48753)
                     /gene="rpsT"
                     /locus_tag="MIV85_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBY2959674.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            49349..49870
                     /locus_tag="MIV85_000298"
     CDS             49349..49870
                     /locus_tag="MIV85_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2959675.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            49904..50680
                     /locus_tag="MIV85_000299"
     CDS             49904..50680
                     /locus_tag="MIV85_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2959676.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            51022..51975
                     /locus_tag="MIV85_000300"
     CDS             51022..51975
                     /locus_tag="MIV85_000300"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBY2959677.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            51993..53012
                     /locus_tag="MIV85_000301"
     CDS             51993..53012
                     /locus_tag="MIV85_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBY2959678.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            53043..53294
                     /locus_tag="MIV85_000302"
     CDS             53043..53294
                     /locus_tag="MIV85_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959679.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            53576..55381
                     /gene="lepA"
                     /locus_tag="MIV85_000303"
     CDS             53576..55381
                     /gene="lepA"
                     /locus_tag="MIV85_000303"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBY2959680.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            55530..56867
                     /locus_tag="MIV85_000304"
     CDS             55530..56867
                     /locus_tag="MIV85_000304"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBY2959681.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            57100..58413
                     /locus_tag="MIV85_000305"
     CDS             57100..58413
                     /locus_tag="MIV85_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBY2959682.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            58585..59760
                     /locus_tag="MIV85_000306"
     CDS             58585..59760
                     /locus_tag="MIV85_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBY2959683.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            59863..60882
                     /gene="hrcA"
                     /locus_tag="MIV85_000307"
     CDS             59863..60882
                     /gene="hrcA"
                     /locus_tag="MIV85_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBY2959684.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            60912..61532
                     /gene="grpE"
                     /locus_tag="MIV85_000308"
     CDS             60912..61532
                     /gene="grpE"
                     /locus_tag="MIV85_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBY2959685.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            61624..63471
                     /gene="dnaK"
                     /locus_tag="MIV85_000309"
     CDS             61624..63471
                     /gene="dnaK"
                     /locus_tag="MIV85_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBY2959686.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSESEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            63682..64836
                     /gene="dnaJ"
                     /locus_tag="MIV85_000310"
     CDS             63682..64836
                     /gene="dnaJ"
                     /locus_tag="MIV85_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBY2959687.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            65802..66737
                     /locus_tag="MIV85_000311"
     CDS             65802..66737
                     /locus_tag="MIV85_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBY2959688.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            66773..68146
                     /locus_tag="MIV85_000312"
     CDS             66773..68146
                     /locus_tag="MIV85_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2959689.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(68334..69101)
                     /locus_tag="MIV85_000313"
     CDS             complement(68334..69101)
                     /locus_tag="MIV85_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2959690.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(69131..70240)
                     /gene="ugpC"
                     /locus_tag="MIV85_000314"
     CDS             complement(69131..70240)
                     /gene="ugpC"
                     /locus_tag="MIV85_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBY2959691.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            70674..70850
                     /locus_tag="MIV85_000315"
     CDS             70674..70850
                     /locus_tag="MIV85_000315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959692.1"
                     /translation="MNLKKKEKIVKPVLKKLTEIVLNILSKKILNYAIYAISVLIVTK
                     VVINIDLYISILYY"
     gene            70951..71688
                     /gene="cas6"
                     /locus_tag="MIV85_000316"
     CDS             70951..71688
                     /gene="cas6"
                     /locus_tag="MIV85_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBY2959693.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            71693..73168
                     /locus_tag="MIV85_000317"
     CDS             71693..73168
                     /locus_tag="MIV85_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959694.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFCELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMEKNVKRIVDIVIKSN
                     IEIDEIDKLDLKQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRIDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     MNTRNLGKKMINNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGREEYKMKNYIESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            73188..74204
                     /gene="cas7i"
                     /locus_tag="MIV85_000318"
     CDS             73188..74204
                     /gene="cas7i"
                     /locus_tag="MIV85_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBY2959695.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYRDKVHA
                     KTSIATITYDLRRILHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKEKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEREENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEEDGKLLLPEERKFMSKELREK
                     AVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGV
                     IETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMW
                     YLKE"
     gene            74220..75017
                     /gene="cas5"
                     /locus_tag="MIV85_000319"
     CDS             74220..75017
                     /gene="cas5"
                     /locus_tag="MIV85_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBY2959696.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            75044..77452
                     /locus_tag="MIV85_000320"
     CDS             75044..77452
                     /locus_tag="MIV85_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBY2959697.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            77894..78841
                     /gene="prmA"
                     /locus_tag="MIV85_000321"
     CDS             77894..78841
                     /gene="prmA"
                     /locus_tag="MIV85_000321"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBY2959698.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKRKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            78860..79618
                     /locus_tag="MIV85_000322"
     CDS             78860..79618
                     /locus_tag="MIV85_000322"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBY2959699.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            79620..80918
                     /gene="mtaB"
                     /locus_tag="MIV85_000323"
     CDS             79620..80918
                     /gene="mtaB"
                     /locus_tag="MIV85_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBY2959700.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            80961..81311
                     /locus_tag="MIV85_000324"
     CDS             80961..81311
                     /locus_tag="MIV85_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBY2959701.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            81474..81653
                     /locus_tag="MIV85_000325"
     CDS             81474..81653
                     /locus_tag="MIV85_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBY2959702.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            81683..82126
                     /locus_tag="MIV85_000326"
     CDS             81683..82126
                     /locus_tag="MIV85_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBY2959703.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            82237..82734
                     /locus_tag="MIV85_000327"
     CDS             82237..82734
                     /locus_tag="MIV85_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBY2959704.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            82927..83490
                     /gene="raiA"
                     /locus_tag="MIV85_000328"
     CDS             82927..83490
                     /gene="raiA"
                     /locus_tag="MIV85_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBY2959705.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            83703..83939
                     /locus_tag="MIV85_000329"
     CDS             83703..83939
                     /locus_tag="MIV85_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBY2959706.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            83952..85295
                     /gene="yqfD"
                     /locus_tag="MIV85_000330"
     CDS             83952..85295
                     /gene="yqfD"
                     /locus_tag="MIV85_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBY2959707.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            85234..86349
                     /locus_tag="MIV85_000331"
     CDS             85234..86349
                     /locus_tag="MIV85_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBY2959708.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            86406..86867
                     /gene="ybeY"
                     /locus_tag="MIV85_000332"
     CDS             86406..86867
                     /gene="ybeY"
                     /locus_tag="MIV85_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBY2959709.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            86873..87592
                     /locus_tag="MIV85_000333"
     CDS             86873..87592
                     /locus_tag="MIV85_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBY2959710.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            87711..88112
                     /locus_tag="MIV85_000334"
     CDS             87711..88112
                     /locus_tag="MIV85_000334"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBY2959711.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            88176..89069
                     /gene="era"
                     /locus_tag="MIV85_000335"
     CDS             88176..89069
                     /gene="era"
                     /locus_tag="MIV85_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBY2959712.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            89081..90460
                     /gene="mgtE"
                     /locus_tag="MIV85_000336"
     CDS             89081..90460
                     /gene="mgtE"
                     /locus_tag="MIV85_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBY2959713.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            90533..90688
                     /locus_tag="MIV85_000337"
     CDS             90533..90688
                     /locus_tag="MIV85_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBY2959714.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            90654..91427
                     /gene="recO"
                     /locus_tag="MIV85_000338"
     CDS             90654..91427
                     /gene="recO"
                     /locus_tag="MIV85_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBY2959715.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            91420..92019
                     /locus_tag="MIV85_000339"
     CDS             91420..92019
                     /locus_tag="MIV85_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBY2959716.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            92179..93057
                     /gene="glyQ"
                     /locus_tag="MIV85_000340"
     CDS             92179..93057
                     /gene="glyQ"
                     /locus_tag="MIV85_000340"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBY2959717.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            93057..95123
                     /locus_tag="MIV85_000341"
     CDS             93057..95123
                     /locus_tag="MIV85_000341"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBY2959718.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKILIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(95289..96836)
                     /locus_tag="MIV85_000342"
     CDS             complement(95289..96836)
                     /locus_tag="MIV85_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBY2959719.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            97116..97883
                     /locus_tag="MIV85_000343"
     CDS             97116..97883
                     /locus_tag="MIV85_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBY2959720.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            98166..98363
                     /locus_tag="MIV85_000344"
     CDS             98166..98363
                     /locus_tag="MIV85_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2959721.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            98392..99468
                     /gene="vorB"
                     /locus_tag="MIV85_000345"
     CDS             98392..99468
                     /gene="vorB"
                     /locus_tag="MIV85_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBY2959722.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            99471..100190
                     /locus_tag="MIV85_000346"
     CDS             99471..100190
                     /locus_tag="MIV85_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBY2959723.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            100203..100742
                     /locus_tag="MIV85_000347"
     CDS             100203..100742
                     /locus_tag="MIV85_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBY2959724.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            100899..101957
                     /gene="buk"
                     /locus_tag="MIV85_000348"
     CDS             100899..101957
                     /gene="buk"
                     /locus_tag="MIV85_000348"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBY2959725.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            101975..102868
                     /locus_tag="MIV85_000349"
     CDS             101975..102868
                     /locus_tag="MIV85_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBY2959726.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            102898..104106
                     /locus_tag="MIV85_000350"
     CDS             102898..104106
                     /locus_tag="MIV85_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBY2959727.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            104130..105389
                     /locus_tag="MIV85_000351"
     CDS             104130..105389
                     /locus_tag="MIV85_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2959728.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
BASE COUNT        41941 a        11252 c        18619 g        34056 t
ORIGIN      
        1 tagattttgg gtaaataaaa taatataaaa tataaatttt aataaaaata ataaagtata
       61 tattattgct ttaataagaa tgtaaaaaat atttttaaat tatcatttaa tgtaatttaa
      121 atgaattgaa gatatatgtt tattgtatgc aattgttgta tttttaggtt ttttgtgatt
      181 aattaaaaaa ttataaaaat cgtttacatg ttgattttta aaaaaaaaag atatagaatt
      241 atatagaaag taataaacaa aaattggatt tacgggagtg gaatgaaatg atgaatgtta
      301 ccttaacaga tgtaaaagag gctagagaga ccattaagaa catagtaaaa agaactgact
      361 tacttgaaag tgttaaactt agcgaaaaaa caggagcaaa tgtgttctat aaatgtgaga
      421 atcttcaaaa aacaggttct tttaaattaa gaggagcttg taacaaaata gcgagtttaa
      481 cagatgaaga aaaggcaaat ggagttatag cttcaagtgc agggaatcat gctcaaggag
      541 ttgcattggg agcaaaaatg actggtataa aatctacaat agtaatgcca gcaactgcgc
      601 ctttagcaaa agttagtgca actaaaggtt atggagcaga agtagtttta aatggtgcgg
      661 tttatgatga tgcatatgca aaagctgttg aaatacaaaa agaaacagga gcaactttct
      721 tacatccatt caatgataag tatgttatag caggacaagg aactatatct cttgaaattt
      781 tcgaacaatt agacaataaa gttgatacta tactatgccc agttggtgga ggaggaatca
      841 tctctggtgt tgctgttgca gcaaaagcat taaatcctaa tgtaaaaata gtcggtgttc
      901 aaactgcaaa tataccttca atgaaagagt caataaaaaa tggaaaagta acaacagcat
      961 ttaatgatac tacaatagct gatggtatag ctgttaaaac tccaggagat ttaacttttg
     1021 aaataataaa tgaattggtt gatgaaatag tagtggttga agagacagaa attgcagaat
     1081 caatattatt tatgatggaa agtcaaaaaa tagtttcaga aggtgctggt gctgtatgta
     1141 cagctgctat attaagtggt aagtatgtac cagcaaaaga tgaaaatgta gtttgtataa
     1201 tatctggtgg taatatagac ataaatacgt tatatagaat aataggtgtt gctttagcta
     1261 aagaaggaag aagatattca tttagtacaa ttatggaaga taagccagga aactttgctg
     1321 agttaactag aataataagt gagaatggtg gaaacatttt aagtgctaat caaggtaaat
     1381 tatcagcagg ggaagctcta ggaaaacaaa gtgcggaatt tatattagag acaatagatt
     1441 atgaccatat agctagaata aagaaagcta tagaagaaaa aggttttaaa attatagaat
     1501 tataataaaa agtgtatata atatacaaga aaaatagtat aatagtgtat gaagatacat
     1561 tttatgtgta ttagattaac gaattaggag gattttaaaa tgaaacatga agtaatacat
     1621 actaatgatg caccagcagc tttaggacca tattctcaag ctataaaagc tggaaacttg
     1681 ttatttgtat ctggacaagt tcctcttgta ccagagacta tggaagtagt tgaaggagat
     1741 gtacaagctc aaactgctca atctttaaaa aatcttaaag ctatattagc tgaaagtgga
     1801 gctgattttt caaatgtagt taagactaca gtatttataa aagatatgaa tgaatttggg
     1861 gctataaacg aagtttatgc tgaatatttt ggagaaaata aaccagcaag agcttgtgta
     1921 gaagttgcta gattaccaaa agacgttaaa gttgaaatag aagtaatagc tgtattataa
     1981 aaatacaata tttttaattt gaaaaggctg aaaaactata ttctagtgat tcagcctttt
     2041 tataaaaaaa taaatcacaa taaagaacat gataaatatt gtcgaattaa aaaataaaat
     2101 taaaataaat attgcaatat ttttgagaag gttttataat gagtatataa tttgaaacgt
     2161 gtaactatta aattaggcat gagttcttgg atatttttat cctgaggatt catgcctttt
     2221 ttgtattgaa attcaaaaat ctatttaata aggaggaagt actgtgttaa attttttcaa
     2281 gaaaaataaa agctataagt tacatgcagt agtgagtggt aacagcatta atattgagaa
     2341 agtaaacgat tctgtgtttt caaaaaagtt aatgggagat ggagttgcaa ttattcctaa
     2401 tagtaatgtt gttgtagccc cttgtaatgg taaagtaact gtgcttacag aatcaaagca
     2461 tgcctttggt atggtctcag atgagggtgt tgaaatatta gtccacatag gaattgatac
     2521 agttagttta cagggtgagg ggtttaaaaa tgaagtgtct caaggagata ctgttaaaaa
     2581 aggtagtcca ataataagtt ttgaaagaga aaaaataaat tctcagggaa ttgattgtac
     2641 aacaataata attgtattaa atcatagcga attttcagaa ataaattgca tggtagaaaa
     2701 tgaagttgtt gcagggcaag atactgttat tgaaattatg aaataataga aagggattaa
     2761 ttcaatatga gagtagtaaa aatctttaat aataatgcat tatctacagt aactaatgat
     2821 aggaaagaag ctattttact aggtcttggt ataggtttta ataaacgtcc aggagataaa
     2881 gttaatgaag ataaaataga aaagatttat tatgttcaag accacatgca aacaaaattt
     2941 ttagaattat taaaaaatgt tagtccagaa gtgatggatg cttcacaaca aattataagt
     3001 cttataccag gaaatgaggg aaaatttaat aataaaggga tattatcttt agtggaacat
     3061 attagttttg caatagatag aatgaaaaat aatgtttttt tacctaattt aatgcttttg
     3121 gatataaaga tgatgtattc aaaagagttt gaattaggag taaaagcttt agaaattata
     3181 tatagagtat gtcatatcca tttgcctgaa gatgaagcag gttacatagc tttacatttt
     3241 gtcaatttac aatcaaatga taatttggca tatgatactt taaaatttgt aaaaggtagt
     3301 attgatttga ttaaagaatg ttatggatta gaattagacg aatcgagttt aagtacatta
     3361 cgttttagaa ctcatcttaa atttcttgct caaagaattt ttaagaatga aatttgtcag
     3421 gatgataaaa tgattgaaat gtatgattat ttaattaaca atcatcctaa aaataaagaa
     3481 tatttagaaa agttaaatgt atatattgaa aaggagttta ggtataaatt agataaacct
     3541 gaaaaaattt atctactact acacctaaca aaaatcttat aagaatgaga tgaattagta
     3601 atagaaatat atataatttt agggggggat aagattgaaa gaaaaactac ttggaggact
     3661 ggaaacattt gcaaaggcaa tggttcagcc attaatgtat ttatcgagtg caggaatatt
     3721 aatggtggta ggtgtactac ttacaaatga tatgttatta ggagtacttc cattttttaa
     3781 atgggagcca attcaaatat ttggaagcct aatttataac tgtataatgg ctattattaa
     3841 taatcttgct gttatatttg ctataggtat tcctgctgca ctagcaaaaa aagagaagca
     3901 caaagcagcg ttaataggat ttatgagtta tataatatac cttacagctt ccaacactat
     3961 gttaacatca ctaggtcaac tagcaaaaga aagcaagatg cttggactga tagggactgg
     4021 acaagctact attttaggta ttcaagttgt agatacaagt gtatttggtg gaattatttt
     4081 agggtatata gctggatatg tatttaatcg tacaagcaac aaaacattta aaggagcttt
     4141 acagatatac tcgggagcaa attttagttt tatatgcatg ttctttgtat ccattttaat
     4201 tggagttgtg agtaacttta tatggccatt agctcaacaa ggaatagctt ctcttgcaaa
     4261 tgtcatcaaa gatacaggta catttggttt attcttatat ggttttttag agagaatatt
     4321 agtaccaact ggacttcatc atttaattta tacaccattt cagttttctg atttaggagg
     4381 agtgcttaaa gttggtgcag atacagtttc aggagcctat gctatagtta tgacagaaat
     4441 gaatttacca gttgagcgtt tctcagatag tatatactac atggcaactg gatttacaaa
     4501 gatgtttggt tatataggta taggagctgc ctttatttat actgcatata agcaaaataa
     4561 gaagaaggtt aaggcaacga ttattccact aataattacg gcagtattag cctctgtaac
     4621 agaaccatta gactttatgt ttgtattctg tgcaccactt ttattctttg tacatgcagt
     4681 tatagctggt ctttttatag ctttattaaa aatatttgat gttactgcat tatgtggagg
     4741 gaacttatta gtatcagtta taatgaatac tacagtaggc gtagaaaaaa cacactggcc
     4801 agtaatgatg atattaggac ttgcacaaat tattgtatat tttgtagtat ttagtttttt
     4861 aattaagaaa tttaattata aaactccagg tcgtgaagat gagagtacag ctacaggcga
     4921 agaacaatca aaacaactta atttagatgc agggatagaa aatataattg atgggttagg
     4981 cggaaaagaa aatattaata cagtagaaaa ttgcatcact agattacgtg ttaatgtaaa
     5041 agatgaaagt aagattaatg aagatataat taatttaacg ccaaatagcg ggattgtaag
     5101 gaaaggaaaa gatatacaaa taatttttgg acttcatgtg catgaggtaa gacgtgcagt
     5161 agaagatttt ttagaagctt attaaagata tatatttata tagcaagggt aaataacagc
     5221 tttaagtgct gtttactatt tattaaagat acatataatt tatagaggag gaataattat
     5281 tatgattatt actattgttg gtggaggaag cacatttact ccaggtattg ttaagtcaat
     5341 tgcattaaga gaaaaagagt tagagcttga ggaaattcgt ttatttgata ttgataaaaa
     5401 acgtcaagat aaagtagctg tagttgtcaa ctggatacta aaagaagatg ttaaaacaga
     5461 tgttaaacta actgtaacta attgtgaaaa agaagcgtat acagatgcta catttatatt
     5521 tgcacaaatg cgtgttggta aatatgaaat gcgtgagcag gatgaaaaaa ttccattgaa
     5581 atatggttgt gtaggtcaag aaacttgtgg ttgtggaggg atggcatacg gactgcgtac
     5641 aatacaacca atgataaagg ttattgatga tgtagagaaa tatgctaaaa aagattattg
     5701 gatattaaat tactctaatc ctgctgcaat cgtttctgaa gcttgtcgta agttaagacc
     5761 aaatgcaagg attataaata tctgtgatat gccaatagct attatagata tgatagcggg
     5821 gtcattaaat atcaatgacg ttcataatat acgctatgat tattttggtc taaatcattt
     5881 tggctggttt acttcaatag attataaaca tagagactta atggaagaga ttaaggaata
     5941 cataaaagaa aataaaatat tattaccaaa atcttatata gaaaacttaa ataaaagtcg
     6001 tagtacagga aatcgccatg ctgtaagtag ctggatacat gtttgggaat ctgtttatac
     6061 aatgttagaa agcttcccaa aatatctgcc aaacacttat ttaacatact atcttttaag
     6121 taaagaaaca gtggaacatt caaacataaa tcgtactcgt gcaaatgagg ttatggaaag
     6181 ccgtgaaaaa gacttatttg aaggtgtgag acattactta gaaactggag aaatttctga
     6241 aaaagcattt tatgcaggtt cacatggaga ttggattagt gatttggcag tttcaattaa
     6301 aaatgataca cgtagtcgtt ttttagttat aactgaaaat cgtggagcta taccaaacat
     6361 gccatatgat gcaatggtag aaattccagc atatattggt aaagatggtc cagaagttat
     6421 tgctcgaggt ccaatacctc tatttcaaca aggattaatg atgcaacaac ttaacagtga
     6481 aaaattgata gtagaagctt atatagaaaa tagttatgaa aaagctttac aagcattcac
     6541 attaaataaa actattccaa gtatgaatgt tgctaaagaa attttggatg aaatgataga
     6601 agttaataag gaatactggc cagaattaag atagtaggat aaaagaaagg gtttttattt
     6661 aatcattaga tatgttttca gagtctttta tcaaaatgta ttcacaaaca tatggcaata
     6721 tattaaaata aagagtgata tttttagaag aatggggtga tgcaatgaac attataaata
     6781 aaattttttg gcaagaagat aggattggca tgattacaaa taatttagag gcagatacac
     6841 atagccactg tatgttacaa ctgttcttag ggatagaaga cagcattgaa ataacagtta
     6901 atgaaaaatt agttaaatgt aattgtatca tagtagataa aaatatctct cattcatttt
     6961 cagcaagaaa aaaagtttat tactctgcta ttattgaacc tacatctata tatgcagaac
     7021 agcttacctc aaaaatgaat gattttggct actggatatg tgacaatgat ggattagaga
     7081 aattacgtca acaaggaact tttttgatat ctaactctag taaagaacaa tatttaagat
     7141 ttatggaaat gcttaataac tatttgaata tacctataac tctcaaacat tatgatgaca
     7201 gaattactga attgttcaat ttattacata cttgtaattg tgataatcat actatttcaa
     7261 gttttgcaga taaagtgtct ctatcagcaa gtagattatc acatctgttt aaagaacaaa
     7321 tagggatacc tttaaaaagc tatatcttat ttcatcaaat ggagtgtgct tttagagaat
     7381 tactttctgg aaaaaatgtt accgaagctt ctatgactgc tggattcgat actccatcac
     7441 actttgcagg gacagttaag cgaatgatgg gaatgcctgt ttctttatct ttgaaagata
     7501 gcgagttttt gaaagtatat taaatattct cgttatataa tgaagttgta ctaagaaagg
     7561 ggctttgtta tgaataaaga atatttagaa gaaacaaaaa tgttaaatta taatgaacca
     7621 caacttaagc ttttggtatc atcaaagaat tggttggaat tagatgattt tcataaaata
     7681 aaatctattt atgagtttgt acagaatgat attttatttg gatataatgc ttctgatatg
     7741 ttaagcgcaa cacaggtatt aaatgatggt atgggacaat gcaatacaaa agctactctt
     7801 ttaatggcat tattacgtgc agtgaatatc ccttgtaggc ttcatgcttt tgatgtaaca
     7861 aaagattttc aacgaggagc tacatccaaa ttgatttcac tattagcacc aaaatatatt
     7921 cttcatactt gggtagaggt attttatcaa gataggtgga ttgctctgga gggtgtcata
     7981 actgataaaa aatatttaga agcaattcag aagaaatttt ttaatcatgg tggaacgttt
     8041 aaaaagtatg caatagctac aaatgatttg aaaaatacat ctattgattg ggatggtaaa
     8101 gatactttta tccaaaaaga agctatcgtg tatgattatg gtatttttcc atcaccagac
     8161 gtattttttt ctactcattc acaacatatg tcaaaattaa aaaatttcat atatgtacat
     8221 cttatcagaa aaataatgac aaaaaatgta tgtaaggcta gaaacaatta tattgataaa
     8281 aatgaatgag tgtttaagag gtaactatat aggaaatata tagaataatt aaaactgtac
     8341 tggttaaaat gaataaaaag gagttatcac agagcaaact taaattgttc ataggataac
     8401 tccttttctg tattaacttc taataatttg atgtcttttt ataaaacata tagatacaat
     8461 taaaccagta aatgcaagag tagctgctat tgaaaatgca acatctattc catgaatgtt
     8521 agacagcatg tttgaactca tatgagcttt cttagtagca cttgtcatta tagtaataag
     8581 tatagcagaa cctatagctc cagatatctg acggagtgtg ttattaattg ctgtggcatg
     8641 agatataagt tctctatcta atgttttaat tccccatgta gttaatggca ttaaaaccat
     8701 tgaaatacca atcatacgaa tacaatacat caatgacaca tgaattaaag atgtatctct
     8761 gcctaaaaaa gcgaaggata aagttcctaa aaacaaacat cctgttccta atattgatag
     8821 agcatgaggt ccatatttat ctaaatgacg tcctgcaatt ggattgagta caaccatcaa
     8881 tatagcacca ggtaacatta atgaacctga agataatgca gaaaatcctc ttacagattg
     8941 aacgtacaga ggaatcatta atgtagcaga catcattgag gcatatacaa tcataattaa
     9001 tattgtagaa ataagaaatg gtttattttt aaaaaccctc aattctaaaa aaggttcttt
     9061 agattttaat tgacgcaatg taaataaaat taatgacata attcctatta atattggtaa
     9121 atatgtggca atattagtcc acccataatt accttgatta gtaaatccaa ttaataaacc
     9181 accaaaacct agagatgata gtactattga aggtatatct aattttagtt tttgagtttc
     9241 cccaacattt cttaataaaa taaatgatag tataacatct aatatagcaa taggggaaag
     9301 aaacagaaat aaactatgcc aaccaaatga atctactaac catcctgata aagttggacc
     9361 tattgctgga gcaaatccta ctgtaatacc aactaaactc atagctgcac cacgtttttc
     9421 ctcagggcat aaatagagta taataacttg taaaagtggc attagagaac cagaacccat
     9481 tgcctgcaac acacgagcaa tcaacatagt tgaaaaatta ttagaaaaaa gtgcaataat
     9541 acatcctata gaaaagatag acattgatgt aataaataac tttctagtac taaatcgatt
     9601 tattaaataa gctgttgtgg gtacaataat acctgcaata agtagataaa ttgttgttaa
     9661 ccactgacca acatcagcag taattttaaa atctgacatt atattaggta atgctgttga
     9721 caatagtgtt tgactgagag aacttataaa agcaccagtc attacaattg ctattattaa
     9781 atttcctttt ttattgttac tttgggtttc cataatttat aacgtctcct tttttaattg
     9841 atttttaatg ctgttcaata aaagtacttt tggtcttaaa gtgtcttctt tttctaaata
     9901 tgcaatcatt gcatccataa ttaaagaatc atattgttga ttttttccct cgacgtataa
     9961 tttttttatt gcttctagta atttaggatt ttcaaggaga gaagtatcag ttttgattag
    10021 ttcttctata tcttgtatca ttttaaaaaa tagcgattta ttatgaaggg aaaagtaaac
    10081 ttcatcttct tgtttatgta aaaacattga tttttcaatt aaaggattta gattatccat
    10141 attttctaca actaaatcta gaatttgtat agtaaatttg gcaataaagt atacatttat
    10201 ttctcttttt tgtacatgaa taatgtatat aaactgatga attagagcat ccaataagaa
    10261 aactaaatca aatataattt tttctatttt atcaccatag ttatcaaata agcttaattt
    10321 gtattcattc aataagttag ctcgtgattt tgtttgcaat ttacttgtag ccttacgttg
    10381 ctcttcagaa aaattttctc ttatataggt atttatggta gttctagaaa aaatattttt
    10441 ccatacagca attatctttc tgtttaactt ttctgatgct ggaatgtcat tattttcatt
    10501 tatggaatgt ataatttcta aaaacttttc atcataataa ttgattattt cgcagataaa
    10561 actttcctta gtttcaaaat gcttgtaaaa agtagcttta gacattttac actcttttac
    10621 aacatccgat attgaagtat tttgaaaacc cttttggtca aaaatttttt gtgcaatagt
    10681 tataatgagc ctttgttttt ctgtcacttt attatctcct ttcacgcaaa aacgtttagt
    10741 actatagagt acctacaagt tttaataaat atattataca tcatttggaa aaaaaatcaa
    10801 tatatagact gtaatatgaa atttttgaaa aatttgttgt tatttttagt cgtataaaaa
    10861 agaaacttaa gagtttctta agaattgttt aaagaagttg caataaatta gtggtatgat
    10921 tatagtatga aagagaatgt cttgaaattt ttctgtatca aattccaatt atggaggtgt
    10981 agtatatgaa aaagaaaatt tgtgtagcaa taatttttgc tctatttata gtttttgtag
    11041 aaatgtttat tgatagctct agcgaaggaa gtaaaattat gacagctgaa ttaagtaaat
    11101 acaggaaagg cgtaaatgta ttatcaataa acaatattat agtagcgaat aaaaaatata
    11161 gtttgcccaa agattattct cctcaggaaa gcagtgaagc gagagatgct ttttataaaa
    11221 tgaataaaga tgctcaaaag tcaggattaa atttaaaagc ttttagtaca tatagaagtt
    11281 atgaatatca agatagatta tttaagtcat atgtaaaaga acatggagaa aaagaagcaa
    11341 atagattttc agctaaacct ggagagagtg agcatcaaac tggacttgct tttgatattg
    11401 gaggagatga ccagtcttgt tgggcaaata aaaagttcaa caatacaaaa gaagctaagt
    11461 ggttgtatga aaatgcatat aaatatggtt ttatacttag atatccagaa ggtaaagaga
    11521 atataacagg atatatgtat gaatcttggc actatagata tgttggaact gaacatagca
    11581 aaaactttgc aatgaataat ttgactttag aagaatattt acatataaat taagagatgg
    11641 tttgttaaaa ttaggttaaa ataaaaaata acctagacta ttagctgtgt aaagtgatat
    11701 aatgtaaata caatttagat aactactcga aggggagtag cttacacgaa agtggtaatt
    11761 aatcgtcaag acagtagaaa tactcggtta attagcaagg gattccttga tagcaagacc
    11821 ttcaaaataa gcattaggta tgtttgtttt ggggtctttt tttattcaag gaatttttat
    11881 ttaaaaaaat ttaaatttca agtatacata agagccccca aacataaaat aaatttattg
    11941 aagaggaggg caacaaatgt cttacaaaag tacttatcaa gaagtaatta aaaatttaga
    12001 ctcaagttta tctggtttga gtaaagaaag agcagaagag ttgttagaaa aaaatggagc
    12061 taatgaatta aaagaagcag ataaggttcc tacttataag cttttcctag aaagttttaa
    12121 agacccatta gtaataattc tattgatagc tgctttagta caaatatttt taggtgaaac
    12181 agtggagtct ataataattt ttgcagttat tattataaac tctgttctgg gtgttgtaca
    12241 aacaaaaaaa gcagaaagtt cattagaaag tttgaaaaat ttatctgcac caaacgcaaa
    12301 ggtaataaga gacaataaaa aaatgacaat tccagcaaaa aatctagtag ttggagatat
    12361 tgtattctta gaagctggcg attacatacc agcagatgga aggcttatag aagcacaatc
    12421 tctcaaggtt gtagaaggga tgttaactgg agaatcagaa ccagttttaa agcatacaga
    12481 aaaaataagt gaagatgtaa gtttaggtga ccagaaaaat atggtattta gtggtgctgt
    12541 agttgtttat ggtagaggtt cttttgtagt gactggaaca ggtatggata ctgaaatggg
    12601 taaaatagct gggcttttag aaagtgctga aaataaactt acaccattgc aacaaaaaat
    12661 agaggatttt agtaaaaaac ttggtgtagg tattgtaata cttgctcttt taatatttat
    12721 aattcaagta gcaagaaatt actttatggc tggaaatgga gaaatgacac aaattatttt
    12781 agattcattc atgttctctg tagcagtagc agtagcagct ataccagaag ctctatcatc
    12841 aatagtcact atagtattgg ctgttggaac aaatagtatg gcaaaaaaac aagccataat
    12901 aagaaaatta ccagcagtag aaactttagg ttcaacaagt gtaatatgta ctgataaaac
    12961 aggtactctt acacaaaata aaatgacagt agttgattat tatatgtatg gaactaataa
    13021 tgatgagtta gataaagaaa aagtaaacta ttcttatcat gctaaattat tgactatggt
    13081 ttctacattg tgtaatgact ctcatataac tagtgatggt aaagaagttg gtgacccaac
    13141 agaagtagct ttaataaatt attcaagtaa aaatgattta gattatgata aattaagaag
    13201 taagtatatc agaataaatg aaataccatt tgactcagac agaaagctta tgtctactgt
    13261 aaatagtata tatggagatt atataatgtt tacaaaaggt gctccagata ttgtgtttag
    13321 tagatgtaaa tatgctttga aaaatggttc aaaagtagat ataacagatg agataataga
    13381 agaatataaa cataaaaatg aagagttttc aaatagagca cttagagtat tagcttttgc
    13441 aataaaagat gtcccagaag aagattttat accttcaatt gatgacgaac atgacatgac
    13501 attggttgga ataatggcaa tgatagaccc accaagagaa gaagtaatgg atgcagtaaa
    13561 agaggcaaag agtgctggta taaaaactgt tatgataact ggtgaccata aaacaacagc
    13621 agcagcaatt gcaaaagaga ttggtataat ggaagaagga gacttggctc ttactggaaa
    13681 agagcttgat gctttgagtg aagaacaact atatgaaaaa ctagaaaata taagtgtata
    13741 tgccagagtc tcgccagaaa ataaaattcg tatagtaaaa gcatggcaac ataagaataa
    13801 tataacagca atgactggtg atggtgttaa tgatgcacct gcattaaaac aagcagatat
    13861 aggaatcggt atgggaagtg gtactgatgt agcaaaagat gcttctgcta tggtattggt
    13921 tgatgataac tttgcaagta tagtaaatgc tgttgaagtt ggtagaacag tatacagtaa
    13981 tataataaaa tcaattactt atctatttgc aggaaactta ggagctatag tatccatagt
    14041 atttgcagtg tttgcaggtt ggtcaaatcc atttacagct ttacaacttt tgtttataaa
    14101 cttagtaaat gactctttac cagcaattgc attagggttt gaaaagtcag aaaaaaatat
    14161 aatgaataaa cctcctagac acccggatga aagtatacta gcaggaggaa cattgaaggc
    14221 agttgctata agaggttgta taataggtgt agttacaata attgcacaat atataggatt
    14281 acaagtatct ccagaacttg gagtagcaat ggcattttca acattgatat tagctagaat
    14341 aatgcaaaca ttacctgcac gttctaataa tcaaacagta ataaaattag gttttttcag
    14401 caataaatac gttataggag cagttttagt ctgtcttggg ctttactctt taacactaat
    14461 accagtgcta agaggaatat tctctatacc aacaacgttt ggattgtacc agttggggat
    14521 ttgcctaggg ttagcattaa tttcatcaat attaatggaa cttaacaaat taataaatag
    14581 aagtgaagta aaataatcaa aaaattaaag ggcatattga ttttaacaat atgcctttta
    14641 taaatagtct aatttattct atattatcga ttatttggaa tgcttttata acttcaggta
    14701 attctttttc ttcaggcatt ctaaatctta tgaaattttt atcaagtcca gtaaaatcac
    14761 ttccagatat aactcttatt tttaatttag caaactcttg ttgtaaatct atgtccttgt
    14821 ttttatgttc aactgtcata attgatacag tatcactagt ttcagctata ttaaggtttt
    14881 tccatggaat taataattga ttttttatat cttttgtttt ttcttttaat tcttctataa
    14941 attgaacatc atctaataaa tttgctgcaa tactacgaga tatttcagac acttcgtaag
    15001 gagtagaaat ctttttaata gggctaacaa gttgttctgg aagaactgca tatcctgctc
    15061 ttagtcctgc taaaccgaat ccttttgaaa atgtttttaa agcaattaca ttatcataat
    15121 tatttagaag cttgacagct gaattttctt ttggcatgta ttcaccataa gcttcatcta
    15181 ccataactgc tatatcatat ttagctgctt cctttactat attttcaatt gatgataaat
    15241 gtataatttg tcctgtagga ttgtttggat tgtctatgta aattacttta tattctggat
    15301 ttattttttc aataaattct ttttcattaa acttgaaatt atcctctttc tttaaaagaa
    15361 cataatcata agttgcacca tgcattttta tatctgtctc atattctgag aactgaggtg
    15421 aatatcctaa aactttatct cccttttcaa taaatagtct atttaaaagg taaataacat
    15481 gtatagaacc atctgccaaa caaattctgt cagtatctaa tgctataaaa tctttccaat
    15541 aatcgactat attatctttt aaagcaattg aatgaggata tcctcttatc atatcaaatt
    15601 ttaaagcatt aaaagcttct acagctttgt ttgagtaaga cacggtattt ataccttcac
    15661 cacagtctat ctcgaataca tcttctgaat gtccagattc tattgcataa ctttttttca
    15721 actgcatttc aatagctttg ttaattttta gtttcatact ttatcactcc ttatttagtc
    15781 aataataaat gttataaaag ttgctagatt taaaatatta tgaaaatata taatagtaaa
    15841 aaatgaatat aaatattata atagctcact ttatttaata tgattatata tcatatattg
    15901 taaaatttct agcattataa gactataaat tgaaaatatt cagaaaaata ctacaagaaa
    15961 cgatttattt tgctcttaaa ataagttaaa tgaatgttat taattttgta aattgaaata
    16021 gtttaagtat aaagttatga tataatctaa taagggtaat tctttagatt atattaagga
    16081 aatataggta tacaataaaa agttatggag ttggattatg ggatataaat taattgtaac
    16141 agatatggat ggaactttat taggcaataa tcataaagtt acagatgaaa ataaaactgc
    16201 actacaaaaa gttataaaaa gcggtattaa tgtaacttta gcaacaggaa gagccttcga
    16261 ttcagctaaa tgcaatgtag attttcttaa agaggacatg ccaataatag cttgtaatgg
    16321 ttcattaata agagagcaaa atggaaatat aatatattca aataagattg atacaagaac
    16381 atgtttaaac attttagatg tattagataa atacgatatt tactaccaat gtaatagtat
    16441 agattctatg ctttcgaaaa aaatagaagg acgtgaagat agattaagtg tatttttagg
    16501 ctctgaaaca gaagtaattg taaaagatga tttgagagaa gaaatcttta aaaaagatat
    16561 actaaaattt gtaatcatag aagaaaaaaa tccatctatt ttagatgaaa taagaaaaga
    16621 attgagaaaa gttcaaggaa taaagataac ttcttcatgg ccaaacaata ttgaagtcat
    16681 gaatgaaggt gttgataaag gtaatgcagt taaaatttta gctgaaaaaa tgaatataga
    16741 cagagaagat ataattgcat ttggagacaa ttacaatgac atagaaatga taaagtttgc
    16801 tggtcttggg gtagctatgg gaaatgcaga agaattgatt aaacaagaag ctgattatgt
    16861 tacagataca aatcaagaca gtggagttgc aaaggcaatt tataaattcc tagagttaaa
    16921 agaatcactt agctcttaaa acagtatata ataggaaaaa ataggttgac tattttgtag
    16981 atagtaatta taatacaaat agataaaaca taaaaattta gattcagtga aaaagagagt
    17041 agatatagag aaaatctcag cgaattgggg gatggtgtga gcctaatgat aacactttat
    17101 attgaaaaga actttggaga atactacttg aaattcagta tggtagtagg taatctcgcc
    17161 ttaagagaat agagtgggta aacattgttt accaactaga gtggtaacac ggaatatttc
    17221 gtctcttggt ctttttgacc aagagatttt ttagtttcat tgagttacaa gacttataat
    17281 taaaatacaa aaaattaaaa tatgaggtga aagttatgaa attatggggc ggacgcttta
    17341 gaaaagcgga aaatcaactt atggaagaat ttaataaatc ttttggctat gattgtgtac
    17401 tgtacaaaaa agatatcgaa ggaagtgtag cacatgttca tatgcaagta aaatgtggac
    17461 ttttaacaga agaagaagga aagtctataa cagaaggttt aaaagggata cttgaagatg
    17521 tagaaaatgg aaagttagta ttggatggag agtatgaaga tatacatagt tttactgaga
    17581 taaatttaat tcaaagaatt ggagatgttg gcaagaagct tcatacagca cgtagtagaa
    17641 atgaccaagt tgcagttgat atgagattgt atgctaaaga aaaagcaaat gatttggtgg
    17701 gtttaatatc tgaatttaaa gctactataa aagatgttgc tgacaaaaac ccagtgatga
    17761 tgccaggcta tactcatctt caaagagctc aagtagtgac atttaagcat cacttaatgg
    17821 catattatag tatgtttgat agagatgaga aaagaataaa aaatgctata gaaatattag
    17881 atgaatcacc tttaggctgt ggagctttag caggaactac gcatgatata gatagaagta
    17941 taacttgtga acaattagga tttaaaaaag tagtagataa ttttatggat ggagtaagtg
    18001 atagagatta tttactagag ctaatgagtg atttttcaat tataatgatg cacttaagta
    18061 gattaagtga agagttgata ctttggagtt ctcaagaatt tggatttgtt gagatagatg
    18121 atttatatac aactggaagt agtataatgc ctcagaagaa aaatccagat ggtgcagagc
    18181 ttataagagg taagactggc agagtatatg gaaacttatt tggtcttttt acagtaatga
    18241 aaggaatacc attagcatat aataaagaca tgcaagaaga taaagaaggt tttttcgata
    18301 gtgtacatac tcttgaaatg tgtatacaaa taatggatag aatgatagcc acactaaagg
    18361 taaatgagga taaaatgaaa caagcagtaa aaaatggttt tttaaatgca acagaagttg
    18421 cggattattt ggttaaaaat aatgttgctt ttagagatgc acatggtata gtaggaagta
    18481 tcgttatata ttgtgaagat aataaaaaag caatagaaga tttaacatta gaagaattac
    18541 ataagttttc agatgctttt aaggaagata tttatgattt tatcgactat gagagtatat
    18601 taaataaggg aataaaaaag aatttaaaat aatgtattta tttttaaaag ctgtaaattt
    18661 gaatgttatc atttaaattt acagcttttt attgtgtaag attttattat ataaaagtaa
    18721 gaaacttaaa agtagtagta tttaaaataa atacaaataa aaaattgtta ttaaaatgat
    18781 aattaatatc aataagtatt gacaaaatta tttctaaata ctattatata taatataaat
    18841 aataatgaaa atcaatatca aataaatggg aggaaatcta atgaacttat tagtgattgg
    18901 tggtcatgaa agaatggaaa aagattatat ggttatggcc aagaaaaaag gttataagac
    18961 aaaggtatat actaccatgt catctaaatt aaataattct ataggaagac cagatgcagt
    19021 tgtcatactt acatcaactg tttcacataa gatgtctaga acggttgagt ctcaagctaa
    19081 aaaacaagat atattaatcg taaggcataa aaatagtagt aaggtagcat ttaatgaatg
    19141 tctagatatg gttgatgaat gtctgggaaa ttgttcaaaa tgtaagctta aagacaaaca
    19201 aaaacaaaaa aatatatagg tataaaaaat acataaacat aaaattaaaa gtactgagat
    19261 aatagttata attattatct cagtactttt agatttataa ggataagtat attataaatt
    19321 ttttattata atttccaact acttgttact ttttcatatt ttttttactt ctagcttttt
    19381 ttcttttttt cttctttata tttgaagcta ttataaataa aactaaaagc actagaatac
    19441 ctgcaataat cttaacaaaa gtcattaaaa tattatttcc agtaaaaaat ggaagactgc
    19501 tatcaagatt attttttgca attaagtcta tactgttttc tagtttacca ttattatata
    19561 catttaaagt accaacctta gccccttttt ttataggcaa atcaatttta tttaactctg
    19621 ttttggtatc ataattgcct tgagattcat ctttttctaa gaatatccta taactatttt
    19681 ttggttcata aatcaattca tgttgttttg taaacaatac ttttttagta tctgtgtatt
    19741 tttctttatc aacaatagta gcacacttaa agttatcaaa tccataatca atcagaatac
    19801 gtgagtctaa atataaatca gcattagttg aattaaatac agcaacgata actcttctgc
    19861 catcttttac agcactcgat aaaagacatt taccagcagc atcagtatat ccagttttta
    19921 taccatcaac tatatcatat tttatattta taggttgacc tttgtatgta atcttatcat
    19981 gtgatgtcaa aaacttatta gtgtttacaa agtatctctc ataaggatat gcttttgtag
    20041 cttcaaattt aagtgactta gtttttacaa tttgtctaaa agtatcatta ttcatagctt
    20101 ctctagctat gagagccata tcatgagctg ttgtgtagtg atttgggtct ggtaatccat
    20161 gaggattatt aaaatgagta ttagtagctc caattttttt tgcctcagag ttcataaggt
    20221 caataaattt ttgtacattg ccaccaccaa catatctagc taatacaaaa gcagcatcat
    20281 tagcagaatg aaccaaaaga gcatctagta actgctttac agtaaaagat tccccatttt
    20341 ttagatacat actagagcca tctatttgag gtaaatcttt aatttctatt acttgattta
    20401 aatctttaac ctcctttaga actaaacaag ctgtccatac tttagttgtt gaagctggat
    20461 aaagcttaga atttccatcc ttattatata gtattttgcc agactcatag tccattaaaa
    20521 ctgcatgttt agcaactata gctggttcat tatctgcaaa agagatatta gagcttccta
    20581 aaaatgaagt aaatatcaat aaacagatta ataaaagtga taaatttctt ttcattgtga
    20641 gcctccaaat tttaaattca tcttttagta tagcatatat ttgtcaataa ttaaaagaaa
    20701 ggagtgatta atatatgaaa aaaaaagtaa aatttatttc gttttttgtt ttatttattt
    20761 taataatatc atcaataatc gtttataaat cgcttatttt caaagatgat atttatgttg
    20821 taagtaaaaa aaatttacct aatgaaaaaa cacatgttgt agagaatgaa attaaaggtg
    20881 aagataataa tcacaataaa gtaactaaag acatagataa aaattttcaa aataataaaa
    20941 taactatata cataagtgga gcagtaaata gacctggaat tgtaactata gagtcagaca
    21001 agagacttta tgatgctgta gaattactag gaggaacgac aaaagaagca gatttaaatg
    21061 gagtcaatct atcagtaaga ttagaagatg aacaacatta cataataccc aaaataggtg
    21121 aagcaacatc tgttacaagt aatgatgatt ccaataaacc aaatcagagg aatgagtcaa
    21181 gaggtgagcc taaaaataaa tccaataaaa atatatctaa cgaatcaaaa gtaaatataa
    21241 atgtagcgac tatagaagag ttggattctc tacctggggt tggagaagct acagccaata
    21301 aaattttaca acacagagaa gaaaatggac agttcagttc aattgaggaa ataaaaaatg
    21361 taaatggtat tggagataaa aagtatgaaa atataaaaga tttaatttgt gtagactaaa
    21421 atataataca aaacttacat atagatatgt tattataaat atgtatgtat atgtgtgtac
    21481 atgtggaaat ttagtaaagg aggcactttt atgaaaaaag aacaaaaaaa acttacagag
    21541 atgacaacag caggtggttg agccgctaaa atagggccag aggttctggc atcagtttta
    21601 tctcaattgc ctaaaaatga taatatagaa aatttattag taggactaga tacagcagat
    21661 gatgctgcag tttataaatt aaatgatgat atggcactta tccaaacttt agacttcttt
    21721 acaccaatgg tagatgaccc atacgtattt ggtcaaattg ctgcatcaaa ttcactatca
    21781 gatgtatatg ctatgggagg caaacctttg gttgctatga atattgtttg ttttccatca
    21841 tgccatgata tggatgtact tgcagaaata ttaaaaggtg ggtttgataa agtgaaagaa
    21901 agtggagcac ttttggttgg agggcatact gtagatgaca aagagcctaa atatggtctt
    21961 tcagtttctg ggattgtaag tccaaataaa gttttatcaa atgctactgc aaaacctggt
    22021 gataagttaa ttataacaaa accaattgga gtgggtgtat taaatacagc catgaaagaa
    22081 ggtatggtag aacaacatat agcagataaa gtaatagaaa taatgataca tttaaataaa
    22141 tatgcagcaa tgagttttga gaaatttgat gtaaattcgg ttacagatat aactggtttt
    22201 ggtctacttg gtcatacttt agaaatggcc aaagcttctg aagtaagtat tgaaattgaa
    22261 tcaaaacatg taccaattat tgaaggtgca atagaaatgg cacaaatggg aattatacct
    22321 gctggtatgt ataaaaatat gcattatgta tctaaagatg tagaagttgt aggaaatata
    22381 gaagttgcag ttcaagatat tttatacgac ccacaaacat caggagggtt gttaatttca
    22441 gtaaaagaag aacttgcaga ggaacttgta aaagatatga aattaaatgg agcaatagaa
    22501 gctaaaatta taggttctgt agttccaaaa ggggaaaaat atattacagt tttataaaat
    22561 attatagaga aagagtgatt gttttgagca aaagagaatt gtttgcaatg ttgccttcag
    22621 ttgatgaagt attaagtgat aatagaattg tagaaataat aaatgaatat cctagaagtt
    22681 tagttttaga atctgtgaga gaagtaatag atttaaaaag acaatttata ttaagattaa
    22741 aagaagatgc atcaaactct gtaacaatag agtttggtga aataatagaa tctgcaatag
    22801 agagagttaa gttaaattac tcattatctt taaaaaaagt tataaatgca actggtacag
    22861 ttattcatac aaatttagga aggtctttac ttagtgaaga tataaaagat gaattatggt
    22921 gtgctgcttc aaggtattca aacttagaat acgatttgga taatggagaa agaggttcaa
    22981 gatactctca tttaactagt acaataaaaa gacttactgg agcagaagat gtactagttg
    23041 taaataataa tgcagcggca gtacttcttg tacttagcac aatggctaaa ggaggagaag
    23101 caattgtatc tcgtggagaa ttagttgaag taggtggttc atttaggatt ccaagtataa
    23161 tggctcttag tggtgcagaa ttagttgaag ttggttcaac taataaaact catttgaaag
    23221 attacaagga ggccattaca gaagatacaa atgtattgat gaaggttcat acaagtaatt
    23281 atagaataat gggattcaca gagagtgttt ctatagaaga attggttaat ttaggtaaaa
    23341 aatataaact acctgtaata gaagacttag gaagtggagt ttttatagat ttatcaaaat
    23401 atggtttatc ttatgaacca actgtattgg attctattcg acaaggtgca gatgtagtaa
    23461 cttttagtgg agataagatg cttggaggtc cgcaagcagg tattatagtt gggaaaaaag
    23521 agtatataga aaaaatgaag aaaaatcaac ttactagagc acttagagtt gataagctta
    23581 caatatgtgc tcttgaagca acattgagaa tgtatttaga tgagacaaaa gctatagaaa
    23641 atatacctac tttaaaaatg ttgacatata aaattgaaga attagaagta aaagcaaata
    23701 aactatttga aaaaataact gctttaaact taaatgcaaa cataaatata gaagatggat
    23761 tttcacaggt gggaggaggg tctatgcctc ttgaaactat aagtacaaag gtaatatcaa
    23821 taactcctga acatatgaat gtttcatctt tagaaaaaaa actaagactt agtgaagcac
    23881 atataatagc cagagtgtat gataataaat atgtactaga tgtaagaact atatttgatg
    23941 atgaatttga tgtaatagtt gaggaattga gaaaagcatt taattaaata aatttgagtt
    24001 aataaatatt aaatttagaa gtataagtat gaagttttga ttaaaaaata gctacacaca
    24061 cttgtgactt tagtcatagc aggtttagag ggggcaaaaa atgaaaaatg tagtaattgg
    24121 aacagcaggt catattgacc acggaaaaac tactcttata aaagcattga ctggaagaga
    24181 gactgatacg ttagatgaag aaaaaaagag aggtatttca ataaacttag gatttactta
    24241 ttttgattta ccaaacaata gaagagctgg aattgttgat gtcccaggac acgaaaaatt
    24301 tataaaaaac atgttagctg gagcatcagg aattgatata gttttacttg ttgtagcagc
    24361 agatgaaggg gttatgccac agacagttga gcatttagat attctaagct ttttaaatat
    24421 caaaaatgga atagtggttc taactaagtc tgatactgta gatgatgaat ttagagagct
    24481 agtaaaagaa gatatttgtg aaaaaataaa aggaactttt cttgaagatg ctgaaataat
    24541 tgaagttgat tctatatcta aaagaggtat agacactctt attgaaaaaa tagataaaat
    24601 gagtgatgat atagaagata aaaatgaaaa ctctccagca agacttaata tagacagagt
    24661 attttcaata aaagggtttg gtactgtaat aacaggcact ttaatagaag gaaagataag
    24721 tatagaagat gatttggtta tatatccaca ggtattaaaa acaaaaataa gaagtataca
    24781 agttcatgga gaaaataaag atacagctta tgcaggtcaa agaacagcaa tcaatatatc
    24841 aaatgtaaaa gtggatgata taaaaagagg agatgtttta gctgcaccaa actcattgga
    24901 ggaatcaatg atgttagatg taaaattatc attggtaaat catttagata aaggattaaa
    24961 gcactgggat agattaagat tgtatcatgg aactagagag atactttgta gagcagttcc
    25021 actagataaa gaattaattg aaagtggaga aagtggctat gttcagttga gacttgaaga
    25081 aagcatagta tctaagaaag gtgatacgtt tgtagtgaga cgttattctc caatggaaac
    25141 tataggtgga ggtgtaataa ttgacccatc tcctaaaaaa cataagaaat ttgatgaaaa
    25201 agttatagaa gcattaaaaa taaaagaaaa aggcgaacta aaagatataa tagaagagta
    25261 cttaaaaagg aatttaaaaa attatccaaa tataaaagaa ataatgagct atagtggtgc
    25321 tcatgaagaa gatgtaaaaa gagcgcttga aacacttata tcagaagata aagtatttat
    25381 tataggaaat atgtatatgc atataaatca atacaataaa ttaaaagaaa atacaataaa
    25441 gcttttaagt gagtaccata agaagtatag gcttagaaaa gggatactaa aagaagaagt
    25501 aaggtctaag atagagagta attttaagac tagggagatg gatattttat tagaaaaatt
    25561 gtctacagaa aatgctataa aaatagaaaa taatatagta tctctattag attttgaggt
    25621 tattttaaat gataagcaaa aagaaatagc aaaaaaaata gaaaaaagat taaaatcatg
    25681 tggagtttct tctatactga caatagatga agtttctgaa ggaaatcata actatgctga
    25741 agtattggag tcaatgatag gtaataaagt agagaaatta gatgatttgt atataatgga
    25801 caaagatatt tatgaaaatg caaagaacat tttgataaat tatataaaag aaaataaaga
    25861 aataacatta ggagaataca gagatttgat tgattctagc agaaagaatt gcatgattat
    25921 attggaaaac ttcgatagaa acaaaataac taaaagagta gaaaacaaaa gaattttgtt
    25981 ttagcagaaa atgtctgttt ttgctttaag gtataaagaa ggaattataa tgtcgagtat
    26041 cgtataatta attagtataa aatattaatt aagaggaagt gtaaagtatt gaagaatata
    26101 atacctgatg taaaaccaga tataaaagaa agagaagaca tgagcctttt atttataata
    26161 atgggctcag tacttttatt atttattata aaagatatag agaaatatga aactttatta
    26221 catgccatat atacgatatt tttagtagct acaggagtaa ttatatttaa tactacaaaa
    26281 tttaaagtag attcattttc tacattttta ggattaattt ttatagctac tggagtattg
    26341 gagtgtatat atttatttaa ttccttgggg attaaaacta agtctataat ggagattaac
    26401 atcacaatat cagcaataac agatttattt cctatactgg gtgtatactt aagttttaaa
    26461 tttgttaagg ataacaaaca aatttattca agtgtaattt tatttatagc aactgctaca
    26521 ttaacaataa catctttatt cataatatca ggaatttgtg actatctggg aaatggtaaa
    26581 tcacaatatg ctttaggagt tataatatct atattcataa taattatttc tatcattagt
    26641 ggaattgaat taaattcaag ttcaaataaa ggtaaatggg aatatgatga aaaaaagatt
    26701 tttaacagaa taatagtaat aataatctta tcaagagttc caaatctatt gcatatagtt
    26761 attgataata gaaatgtaga gaggatatta tcacaaataa taataaatgt agccttatat
    26821 tatttatata attacatagt atctaagaat attaagaaaa cagcactgga attgcatgat
    26881 acgaatgaag aattaacaaa aaaaacggaa agtttaaaag aaaagaataa aaaattaatc
    26941 tatgagacag aaaagataga ggaacttaag ggaatactta tgaaaagaga atctaggcta
    27001 caatctacat tagatgtagc agtaaatagc atagtagtat ttagcaaaga tggagaaatt
    27061 acatatgcaa ataagagctt tagaaatact tttggagact ataaagaaca agataaattg
    27121 actgataaaa taaaaaactt caatgatttg atagaaagca ttcattatgt gtttgttcat
    27181 gagaagaatg cagagaaact tattagtaca agcgataata aagtttatca agctatattt
    27241 gcacctttaa ttattgcttc acaaacagaa ggagtattgt gtgtactaga agataagact
    27301 aagaaaaagg agtacgaacg caaacttatt gaagcaaata agagaagtaa agatttttta
    27361 gaaagtattg gagatggcat agtagtgctt gaaggtaata acaaaatata tgttaataat
    27421 gcatgtaggg aaatttttaa aaataattta gagagtattg atttttcatt agtatgtaaa
    27481 agtgaagaaa gtatagaaaa aagatatgta atagatggtg aagtaaagta tgtagagatg
    27541 agtttttctc agtatactaa tgctggtact aataaaacta ttattgtaat acgtgataca
    27601 acctctcgaa aaatatctca aataaaactt gaggaaagtc aatcatcata ttcaagattt
    27661 atagatatat tacctgatgg catatgctta ttaaaagaag atttaagtat aaactatgca
    27721 aataagtcgt ttttagatat gctagctttt acaaacatag atgatataaa agattctaat
    27781 attaaactat taatgaatgc gaatactgaa gaaaaaatga aatttacgga taatatggct
    27841 aaagttttaa atgaaaatag aagtatactt ttactggaat atgaattgat aaatagttat
    27901 gatgatatag tagaagtaga attaagtgca ttaccttttg ctatatacaa tactagatac
    27961 ataatgctta ttataaaaga tttagtacat aagaaatatt ccgagcaagc agaaaaagaa
    28021 ctgcttgaaa gatttaaaac agataaaatc aaaacggagt tttttgcaaa tatgtctcat
    28081 gaactaaaaa ctccactaaa tgttatatct agttcaaatc aactggtaga ttctttctat
    28141 agaaatgaaa agataaaaga ttacaataac aatattaaat ctcatgtgga tttagttaga
    28201 caaagttctt ataggcttca aagattaata aataacatta tagatttaac aaagatggag
    28261 tctgggttct atacactaaa acttgcgaaa tacaatattg tatctgtaat agaagactta
    28321 tttatgaata tagaagagta tgcacttaga aaagacataa aaattctttt tgatacagac
    28381 cttgaagaaa ttaatgttta tatagacaag gttgaaattg agagaattat gttgaatcta
    28441 ttgtcaaact gtattaagtt tactgataat ggaggctgga tatatgtaag tattcattat
    28501 aaaatagata aagtaatcat aagtgtaaaa gacactggag ttggaatacc acaagataaa
    28561 ttagagttga tttttgaaga attttcacaa gttgataaga ctttatccag aaatactgaa
    28621 ggaagtggaa tagggcttgc tatagttaag aatctagtaa gtcttcatgg tggagatata
    28681 gaagtagtaa gtgaagtgaa taaaggcaca gagttcttaa tttcacttcc aatgaaggga
    28741 tttagtagtg aacattacac agaagataag agaatatata atattcaaga aaaaataaaa
    28801 atagaatttt ctgatatata ttattaaaaa tgattatgag caaaaataaa ataaaaatac
    28861 tatttgttta aatatttaag ttgtaagaaa taggctatca taaggtaaat tattatgata
    28921 gcctattttt agctaggttt tatatctata tgtgagaaca tataatctct aaattacctt
    28981 caaaactaaa atctccaaag tcgtttggta gtataaaatg catacccttt tttaaattgt
    29041 attctacaga attgtgtata agttttccat ttccatccaa cacactgtat aaagaaaaag
    29101 gtgtattgtg tgtaaaatta cattttccaa aaacatctaa tttataaaca ctaaaaaatt
    29161 cgtttgacac aaatgttgtg catttaaagt ctgatgttga tacgatttta tagtcagtat
    29221 cgaaatttat atgaggaaca ttcgtaacat ctattgattt ttgaacatga agttcacgct
    29281 tattacctga attgtcagtt ctatcataat catagactct ataagtagta tctgagtttt
    29341 gttgagtttc taaaatcaat gttcctttgc atatagcatg tatagtgcca cttggaacat
    29401 agaaaaagtc tccctttttt atattaacct ttctaagtag tttgtcccat tcattattat
    29461 ttaccatatt tacaaattct ttatgagatt ttgcattatg acctattata atttctgcat
    29521 catcagaaca atctattaca taccaacact ctgtcttacc taactctcca ttttcatttt
    29581 ttttagcata ttcatcattt ggatgaactt gaactgataa attatcattt gcatccaata
    29641 tttttgtaag taaaggaaac ttatcaccag gtgtgtttcc aaataattct ctatttttat
    29701 tccacaattc agatagtttt ttacctttat attttccatt ttctattaag caatctccat
    29761 ttttatgaga gcttatagcc caacattcac cagttgttgg cgaatctatt tcataattaa
    29821 atttatcttt aagtgcagta ccaccccata ttctatccat aaaaataggt tttaaaaata
    29881 atggttccat aatcctgttc ctcctatgat attaaattta tcctacaaat aattatatat
    29941 aaatagatta taaaatcaat agtaaaaaag ttttgtccct tgaaatgaca taaagtataa
    30001 ggagttatta aataagataa actatgatat ataatataaa gttctaaatt ggagtgataa
    30061 ttatggagtt gtttaaggca gaaagcaaaa aatataaaaa agaattttta aaattattgg
    30121 agcaatgggt tagtatacct tcattttatg atagaaaaac tgtatctaaa gacatgcctt
    30181 ttggaaaagg agtatatgat gcattaaact ggtttgaaaa tctaggtaga gaaaacaatt
    30241 tcaaagtaaa aaatatagat aatcatgctg ttcaaattga atatggaaat ggtaaagagt
    30301 atgtagatat atttggacat tgtgatgttg taaatccagg tgaaggatgg gatagtgaac
    30361 catttaaact aaatattata ggtgataaat tagttgctag aggtgtatct gataataaag
    30421 ggcctatgat agtgaatttt ttagcactaa aaatgataaa ggatttagat attaatttaa
    30481 aaagaaaggt tagattaata gctgggggaa atgaagagag tggatttaaa tgtataaagc
    30541 attattatag caaagagcca tatggtgtat gtggatttac tccagatgct aaatttcctg
    30601 tattaaatgg agaaaaaggt ggagcaataa taaagttaat ttcaaatata gacgataaat
    30661 ctttatatat aagtggtgga atagagttta atacaatacc agataaagtt tatataaaga
    30721 atgtagaaaa attgggtaaa gataatatat gttttgatat taacaatata tcgataaatt
    30781 atgataatgg caattatatt gtgtatggaa aaggtggtca ttcatctaaa cccgaaaaat
    30841 caataaatcc tatattagct acaattaaac ttttgtcaga aaatattgat gaaaaatgga
    30901 caaaagattt atataagttg ataaatcaag ataatataaa tggaaactta tttggtttaa
    30961 atattgaggg gaaatgtgga attttatcaa tggtgccaac aataataaat atagtagatg
    31021 gaaaattaga agtagtttta agcgttagat atccagaaat attaaccatt gaagatataa
    31081 taaaaaaatt taatttgtat atggagcaaa ataatattaa taaatttgag cttattgggg
    31141 aaaatttaaa gcaagcaaat tatatagata gaaattcaaa acttgtaaga agtttgcatg
    31201 atatatatat aaagtattct ggagatttaa aaaatgatgt tagagtaact agtgcaggaa
    31261 gttatgcttc tgaaatgaat aattcagtaa tatttggttg tgaatttcct gatggtagct
    31321 ttggcaatgt ccatagtgcg aatgaatttg ctagcttaga tagatttata actgcaatag
    31381 gtatatatgc agaggcaata attacattat gtaataaaat ataaatacaa aatgtccctt
    31441 atatagacat attatatata caattaaaat tttacttgat atataattga aatcaaagag
    31501 aaggtgatac aatgataact aagaaacatg caataatagt aaagagttta agcaataaag
    31561 atggatatat gacatcaaac gaattagcta tcaaattgga tgtgtctact aaaactatta
    31621 aaagatatat agcagattta aatagtgttt taagcaaata tgatttggta atagcttctt
    31681 ctagaggtat aggatacaag ttaagcggtt ctaaaaacaa tatagccaga gctgttaaag
    31741 aagcaaataa atatattgat ggttttttag atgactctga agagtcaaga atgtcaaata
    31801 taatatgtat gcttattaat agaaattata tgagtataga agcaatggca gaagaattaa
    31861 atctaagtat agccgctata aataaattgt ctagtaagct taaaagaaaa cttgaaaagt
    31921 atgacttagt tataaaatct aaaccttact atggaagcta tatacatggt gaagaaatta
    31981 atataaggca attaattact gactatgcaa taaaattaga tgaaaaaagt aaagtgaagg
    32041 tgtttttaga tgacattagt gaaaacgata tacactgtat agaaagtatt ttagaaaagc
    32101 acttaagaga aaaagataca ataatttcag ataaagattt taatcttttg ctttcaaaaa
    32161 taatcgtttc tgtatttagg agtaagagag gtcatagtaa caatataaac ttaatggata
    32221 caagttatag atttcataac tactacttta tagaaaatct aatgaaagaa atatctgata
    32281 aaattggatt taaacttatt gaagatgaag taatttatat ttcaaattat tctggtgtaa
    32341 tagcctataa aggtacacaa ggaagaaaaa acacaagtga aattgaggaa cgaataagta
    32401 ctgttataag tagtgcactt caagatatat tccttatttc aggtagtgat tatacaaaag
    32461 atgatgagtt tatggttgca atctctgacc atataaagag atttttaaat agagctagag
    32521 ctaatgtaaa atcaaataat cctttacttc atcaaataaa agagaagttt cctatagctt
    32581 ttaatttagc cgtgttttta tcaaataaac tagaaactga gtttaattta aaacttgatg
    32641 aagatgagct tggatatata gctatccact ttgctgcttc aaatgaaaga atgaaaaaaa
    32701 atactagtaa gaaaatttgt atagtttgtc attatgggat aggaacagga caacttattt
    32761 ctgaaaagct aaaacagaat ataagtgatt taagtgttgt gggtgtttat ccagttagat
    32821 atctcgatat ggctataagt caagatgttg atttgatagt atctacagtt gaattaaaag
    32881 gatatgaaaa acctgtctta tatatagaaa atatatttga tgatagctta attgaaaacg
    32941 taaacaaagc cttttatgaa aaggaagaaa gaagaaagat aataagtaac atgtttgatg
    33001 aaaaagcttt tttcagtata aaggctagta ctaaagaaga ggtcataatt tcactttcaa
    33061 ataaactaaa agaaagagat tttatagagg aaagttctat aaaaagtata atagatagag
    33121 aaaatatttc atcaactgaa ataggaaatc tagtagcaat accccacaca atagtgaagg
    33181 gagataaaaa atctataata ggagttggaa tacttgaaaa tccaataatt tgggataagc
    33241 aagaggttca gctagtattt atggtatttt ttaatactaa agaaaaacat aatttctcga
    33301 tatttaaata cctttataat tttataaaag atgaaggagg agtaagagga attattaaaa
    33361 tatgtgactt taataaatta atggcactta taggtaatta aggaggaaat taataatggg
    33421 aacaaacata tttaacaaag aatatgtatt tttaaatgtt gatgctaagt caaaggttga
    33481 agttttaaaa tttatatcaa aaaaagctaa agacttaaac ttggcagaag atgagagctt
    33541 agtatatgaa ggtttaatgg ctagagaaga acaatttact acaaatttag gagaatctat
    33601 agcaatacct cacactaaaa atgatgcaat tgaaaatcca gcagtagtag tattgaagtt
    33661 taatgaagat gttgtttgga atgaaggtga ggataaggtt aaattagcaa taagcttact
    33721 tatgccagga aaaagtaaag agaatattca tcttaaatta ttatcatctc tttcaagaaa
    33781 attaataaat aaagaattta aagattctct tttaaaaagt gataatgttg aagaaatatc
    33841 taacttaata aatgaagctt taggtttata attaaacact aaggttataa aataaaaaaa
    33901 taattaacta aaaataggag gaatttgaaa tgaataaaaa attagtagca ttatgtgctt
    33961 gtccaatggg actagctcac actttcatgg cagcagaagc aatagagcaa gcagcaaagg
    34021 cattaggtta tgaagcaaaa gttgaaactc aaggtgctga tggtgtacaa aatgagttaa
    34081 caagagatga tatattagga gcaactatga taatacatgc agtagcaata acaccagaag
    34141 gtatggaaag atttgatggt tgtgaagttt atgaagttga attacaagaa gctataaaaa
    34201 atgcagaagg tgttataaaa gaaatagaag aagatttagg aatataataa atttattgtg
    34261 gaggaaatag aatggcaatt aagaaaaaag ttataaacag ttcaggtgct tctacaacag
    34321 gaggaaataa tgtaggaaaa tctactccat ctagtccaac tcaatcaaag ggaaatggaa
    34381 aatggaaaga aataagtaaa catataatga caggtatatc atatatgata ccagttttag
    34441 taatgggtgg acttataggg gccttatctc aattaatacc atatgctata ttaggacttg
    34501 acccatctgt aggtatagtt gatgctatga actcaggaga atttacaggg ttcaagctta
    34561 gtcttttaaa tatagcacaa ttaatgtcaa atttcggatt tactttgttt ggatttgcga
    34621 taccactgtt tgcagcattt tgtgcaaact ctataggtgg aaaaacagct ttaattgcag
    34681 gatttatagg tggatatata gctaataaac ctgtaggtgt accacaattc gttgatggac
    34741 aatggactga agttgttcca gttgcatcag gatttttagg tgcaatacta atagcattta
    34801 taataggata ttttgtaaaa tggttaaata aatctataaa agtttctcat aactggttag
    34861 cttttaaaac aacattttta ataccattaa tagcgtcatt agcttgtatg gtattgatga
    34921 tatttataat aactccattt ggtggattaa ttaatgaaag tatgaaaaac ttcttaacag
    34981 cagcaggagc agctggagaa tatgtatatg caacagcttt ggcagcagct acagcattcg
    35041 acttaggagg accaataaat aaagcagcag gattcgttgc acttggttta actacagaga
    35101 atgtacttcc aataacagca agaacaatag ctatagttgt tcctccaatt ggattaggat
    35161 taacaacatt attagataaa agattagtag gaagaagagt atatgataga caattctatc
    35221 aagcaggaaa aacttctata ttcttatcat ttatgggtat atctgaagga gcaataccat
    35281 ttgcacttga gagaccaggt tttgttatac ctttaaacat agttggaagt gtaataggag
    35341 ctattacagg tataattcta ggagcaattc aatggttccc agagtcagct atatgggcat
    35401 ggcctctagt agataactta tttggatata taataggtat agcagttggt gctatattca
    35461 tagcagtagg aaatatattc tatagaaata aattaataaa agatggtaaa cttgttgtag
    35521 attatatcga ctagtattta atttttacta tctataaata actttggctg gtaatatggt
    35581 tttaatcaat attaccagcc ttacctatat gattaattaa aggcggtgga gataagatat
    35641 ggataagata gaaaaagtaa gagagtattt tagagaatat gatatagatg gatttcttat
    35701 aaatagtcct acaaacaagt tttatgttgg aaatttattt agctcttcag gttatgtttt
    35761 tataactaaa gaatcacaat atataatagt agattttaga tattttgaag aaattaaaag
    35821 aaaatctagt ttgtttaatg tagtattaat ggacaaaact agaactcatt ttgatataat
    35881 taatgatatt tgtagagagc agaatataaa ggaaattgga tttgagggaa atgaagtatc
    35941 ttttgattta tatagaagta tgagtaataa gttaagtgca accttaaaat cagttgattt
    36001 atctacatta agggaaacaa aaaatgaaga cgaaataaaa tatataaaaa aagcttgtga
    36061 aatagttgat gctacatttt atcatatagt agactttata aaggttggta tgactgaaaa
    36121 gcaagttgaa aatgaaattg ttagaattat aaaagattta ggtggtcaaa aagaatcttt
    36181 cgatacaata gttgcatctg ggcttagagg agcattacct catggaaaag caagtgaaaa
    36241 agttatagag tatggagatt ttgttacctt tgactttggt gctaagtata ataattattg
    36301 ttcagatatt accagaacca tttgtatggg tactataaat aaagagttag aagaaatata
    36361 taatatagta agaaaagcta atgaagagtg tataagggtt ttaagaccgg gaatgactac
    36421 tggagagata gataaagttg caagagacat aattggttca tatggatatg ccaataattt
    36481 tggtcataat ctgggtcatg gtgtaggaat tatggttcat gaatatcctg cattagctcc
    36541 tgaatcaaat gaagtattaa aagaaggaat gattgtaact atagagcctg gtatatatgt
    36601 tccaagtctt ggaggcgtaa gaatagaaga tgatgtactt ataacacaag atggatgtat
    36661 gagattgact acatctacta aggatttaat agttgtaagc taaaaataaa ttagataaat
    36721 attttataac aataagaaaa gaagaggtaa atttaaatgt ataattttga tgataaacca
    36781 gatagagtaa gtgaaaagtg tagaaaatgg gatttaaata ttataagaga taaatttgga
    36841 gatattagag aagattttat accaatgtgg attgctgata tggattttaa aataccaaca
    36901 gaaatagaaa acaaatttat tgaagctgta agaagaggtg tatttggata tacatactgt
    36961 tatgatgaat tttatgattc agttattggt tggcaaaaaa atatgcatga ggtaaatgta
    37021 gaaaaagaat ggattacatt aacttatgga actgtatcaa cacttcatta tgtagtacaa
    37081 gctttttgta agaaaggtga tagtataata ttaaatacac cagtttatga cccctttgaa
    37141 tcatcagcaa aaaaacaagg tgtaaatgta atttgtaata cattagatgt tgtaaatgat
    37201 agatattata taaattttga taaattagaa gttcaaatta aagaaaataa gcctaaatta
    37261 atgatgtttt gtacaccaca taatccatct ggaaggatat ggacaattga agaaatgaca
    37321 agggtagcaa ctatatgtaa agaaaataat gttattttgg ttgcagatga agtacatgca
    37381 gagcatattc attatggtac atttaattca atacttaaga ttggaaaaga gcttttagaa
    37441 aatgttattc tattgacatc accaaataaa ggatttaatc ttggtggatt aaagacttct
    37501 tattcaatag ttataaataa ggatataagg gacaaattta gaaataaatt aaagcaaaat
    37561 tctataactt ctccaaatgt gtttggaata ataggattga taaccgctta taatgaatgt
    37621 catgagtggt taagtggtgt aaatgaatat ataaaatcaa attatgaact tttagaaact
    37681 tgggtaaata aatataataa gataaaattg atgaaaatgg aatcatctta cttagcttgg
    37741 atggatataa gtggattagg tattagtgca agtgagttta cagataaatt ggctatagat
    37801 acaggagtat tattagaaga tggaagtcat tttgtaaaag atggtgagaa gtatgttaga
    37861 ataaatttag gaactcaaaa ggaaaatgta attgaagcct taaatagaat ggatttattt
    37921 ttaaagtctt tataaaaatt tggttgaatt agtattttat ataaatttaa actattaata
    37981 tggtatatac ataagtagaa tttgttttag attacttaag tatataccat attttatata
    38041 aaaattaaat ttgcattagt catgtgataa ctatttaaat tcatatgtat tttgtatgta
    38101 taatagatat aattattatt taaacttatt gtttatttaa tttttcaata gaaaaagatt
    38161 tatctgtaag tttaaaatta tcttttatac ccttagttaa gtatactttc ttatccttag
    38221 ttatgaatat agcatctaca ttatcaattt tattaattaa attcatacct ttttcaagac
    38281 caagaccaaa tgtagaagtg gataaggcat cacaattaat agatttatca gagattattg
    38341 taacactact taaattgttt tcaaaaggat accctgtaaa tggatttaac atatgatgat
    38401 atatttttcc gtctttttcg ataaatcttt cataaattcc agaagtaaca acagacttat
    38461 ttgtagtttc tatgtttcct atggattcac catttttact agttgggtct tgaataccta
    38521 ttttaaaagg tttatcattt ttaccatttt ctaaagtaaa tatatttcct cctaagttta
    38581 ctaaaccttt ttttacatcc tctgatttta aataggctac aattttatca gcagcatatc
    38641 ctttagctat ggcacctaaa tcaattttca tattttcttt ggttaatttt atagatttat
    38701 ttttttcatc caatatgatg ttcttataat caataagagg cagaagtttt tgtatcttag
    38761 aatcacttgg aactttagct ttatctgttc caatagccca taaatttgat aatggaccaa
    38821 ttgttatgtc aaaatatcca tctgataatt tggaatattg tatagcttct tttacgacga
    38881 aaaatgtatc atcagaaact ctgacaaatt ttttaccagc attatcattt attttagaaa
    38941 catcacttcc tggtatatga gtgctcattt tgttgtcaat atatcttaaa attgaatcac
    39001 attcatttaa gattttatca cttttggatt cttttacatt aaatacagta acttcgttta
    39061 ctgtaccaag gtagtagcta gttttactat atttagtatt ctggcttgaa ctcctaaaaa
    39121 atgaaaataa aattaatgct aaaatcaata tcacaaaaat aaatgtgatt tttttcttat
    39181 tcatggtata ttcctcctat gaaattgtgt tattatttta ttataacata atttcatagg
    39241 aggacaaaaa atgaagaaaa aagacattct tcttatttta ggcattttgg ttgttattac
    39301 agcatgttat gggataataa atgttataaa ttctaaaaat gctggaaata ttgagattta
    39361 tgtagataat aaattgtata aaactgtttc aataaatgcc aaagaagaat ttaaaataga
    39421 gagtagaggg gggtataaca tagtaaagat tcatgataaa ggggttgaga tagtagatgc
    39481 ttcatgccct gataaggttt gcgtacatac tggatttata aacaagccaa gtcaaagcat
    39541 agtttgtata cctaatagag tgagcataaa aataaataca aatgaaaaga atgataatca
    39601 agaagatata atttctaaat aaaataataa aaataattga aaggaattgg tgataattat
    39661 ggttaactta ggaaacgatt gggatgaatt attgaaagaa gaatttgaaa aagattacta
    39721 cttaaactta agaaaatttc ttatagaaga atataaaaca cgccaaattt tcccaaatat
    39781 gcacaatata tatgaagctt taaaacacac ttcatacaaa gacacaaaag tcttaatatt
    39841 aggacaagac ccttatcatg gagataatca agctcatggt ttagcttttt cagttcaacc
    39901 acaagtgaaa actccaccat ctttattaaa tatgtataaa gaattaaaag atgatttagg
    39961 ttgttttata cctaataatg gatatttaat gccttgggca gaccaaggag tgttactttt
    40021 aaatactgct cttactgtta gagcgcatga agctaattct cataagaaca aaggatggga
    40081 aattttcact gatagagtaa tatctatttt aagtgagcgt gaagacccag ttatttttgt
    40141 actatgggga agtaatgcac gtaaaaaagt agagttgatt gatacaagta aacattatat
    40201 tttggaagca cctcatccaa gcccattgtc agcaagtaaa ggcttttttg gatgtaaaca
    40261 cttctctaag ataaatgaaa ttttgaaaaa gctaggaaaa gaacctatta attggcagat
    40321 agaaaatata taaaagtaaa aggtaacaaa atgataacaa aacaacaata aacaatgaca
    40381 ttgttgtaac taatagaaat atgcttaaat agttgaaaat actatgtatg catatttcta
    40441 tttttttgtc aagttgacaa ctcttgaaaa aatagttaca atttagttac acaaaaaaca
    40501 caaataaaaa aagaaactta caaagcagaa ttttatgaag caaaatatat agtgtaaaaa
    40561 atcttaggga ggaaatttta tatgaatttt aaaaaattga gtaatgctaa agtctcggta
    40621 atggcagttg ttttatcagt tggaatatta tcgggatact ctgcgcttaa taaacaagta
    40681 acattagtag taaggggaga agaaagaact atatcaacat ttagttctaa tgtaggagac
    40741 cttttagaat ctcaaaacat tagctatgat tcaaatgata tagtaacttt agatgaaaat
    40801 acaaagttat ctaatggaga taaaatagaa gtaattgatg taaaggaaaa aacagttgta
    40861 gaaactaaag acattccatt tgaagttaca gttgttgaag atggctcttt attaaagggt
    40921 gattctaagg ttaaagaaga aggaaagtct ggtaaaagtg aattaatata taaagaaact
    40981 tatcacaatg gaaagaaagt agaaaaggaa tttgtgaaaa aggttgttaa agctgagcca
    41041 gtaaataagg ttgtaagcaa agggacaaag gtagaaatgc aagtagcctc atcaagggga
    41101 gaaagttcaa gaagaatggc ttcatcatca tctagtagca gtagtagtaa caatggtaaa
    41161 aatatgagag tggtagcaac tgcatatact ggtcacagta taactgcaac aggaacaaaa
    41221 cctaagtggg gaacaatagc tgtagaccct aaggttatac catatggaac taaagtttat
    41281 atacctcaat ttgacatggt gtttactgca gaagactgtg gtggagcaat aaaaggaaat
    41341 aaaattgata tctacatgaa tgattcaaaa acagtttata actggggaag aaaaactata
    41401 gatatacgta tattaaaata gttaaataat ttatattttt actggaaatt atattttgat
    41461 tatatagaga agaaactctt tatagattct aaaaatataa tttccagttt tttattttgg
    41521 atatgtaata aaacaggtaa attttaacca tgtatagata aaagctattt aaattataat
    41581 ttactatcat ataaatctat aaaaattgtt gcaaagagtc aaaatatatg atattataga
    41641 tttcgttgag aaggatttca ttatgggagt ggatgggtgc cggtgtgccc tctagtcttc
    41701 aaaactagta tgaggggtta agagcctctt aggtgggttc gattcccacg cattcccgcc
    41761 aatatgtaaa aggtatcttt taattaaaag ataccttttt aaatttattt taagataatt
    41821 tatttttaat aatatataat gttttgtatt atataatgta aattttctaa tacaaaacat
    41881 tatatattta gataaaaatc taggagtgtg gaaagatgga aaataatttt acaacgagaa
    41941 ctagttttct agttggagat gatgggataa aaaaacttaa taattcaaat ataatagtat
    42001 ttggagttgg aggagttggt agttttactg ttgaagcttt agcaagagct ggagtaggca
    42061 atattactat tgtagatttt gatgatgtag atataaccaa tataaataga caaataccag
    42121 ccctacattc aactgtagga agatacaaag ttgatgtcat ggaagaaaga atattagata
    42181 taaatcctaa tatcaatata aaaaaaataa gaagtcttta taataaagat actagtgacg
    42241 aaatactaac tgaaagatat gattatgttg tggatgcgat agacatggta agttccaaaa
    42301 tacatctaat tgaaacttgt gaaaaaaaag gattgaaaat aataagttct atgggtatgg
    42361 gaaataaatt agacccaact aaaatagtcg ttacagatat acacaaaaca agtacttgtc
    42421 ctctagctaa agttatgagg aaagaactta gggatagagg tatcaaaaag ttaaaagtag
    42481 tatattctac tgaacaacca atagaactta agaagaaagt aatgaatggt agaaaagtaa
    42541 cacctggtag tgtatcattt gtcccatctg taggaggttt aataatcgca tctgtaatag
    42601 taaatgaact attaggacaa taagttttaa atattttaat ttataaattt tatatacaaa
    42661 tttgaaggct agaagcatga atacaaagca attttatatt catactttta gcctaattat
    42721 tttatattac cttattttat gtagttgtag ttttattttt tagattatgt atctatttca
    42781 taattatatt ttgtaaatat aatttctcca tcactataaa aaacaatatc tcctattcta
    42841 tctgttctat aaattgatac atggttttgt tttagattat taataacctc cctatgtgga
    42901 tgaccatatt gatttttata tccacatgat attgcagcta tatctggact aatttttttt
    42961 ataaattcta aagatgaaga agaattactt ccatgatgac ctatttttat aaaattaata
    43021 ttatttaatt taaaagaatg taaaatttct ttttcatttt cttcttcagc atcacccata
    43081 aataaaaaag aattatcatt aaaagttaat ttgaaaacta tagaatttaa attagattct
    43141 tcttgtatat atgatggact taatacatat atatttatat tgttatctat gtttaaaaca
    43201 tcatttttat agagatgctg aatagataag tttttatccg tacaagaatt tattagattt
    43261 tgataagcct tactatcagt tgattgttca ggcatatata tggagtttac attaaatttt
    43321 tttataatat tatcaagact tcctatgtgg tctgaatctg gatgagttgc tattataata
    43381 tcaatagttt ttattctttt ttgtctaaga taactaataa ttatattttc gctatcttca
    43441 tcacctccat caattaatat attcttattt gtgggtgttt gaactaaaat actatcacct
    43501 tgtccaacat caatcatatg tatagatagt agagattttt tgtcacagcc gattaaaagt
    43561 gatattataa taagtattga taaaaaaatt ttatttctca ataaaaaatc actccattca
    43621 ttacatgttt atataaattt atgatgggta atataagata tatatgactt attatatttt
    43681 atattttaaa caatataaat gaaattaata ccataataaa attggagttt tttatatata
    43741 caaaataaaa tttttaaaat taagcaataa aaaaggtagg aggattttat gtttttcaaa
    43801 gatattgaac taaattcaaa aaaagagtta gacccatatt ttgatttagt agattatgaa
    43861 gcttgtgagt actgttttag tactttatat atgtggcaac atgtttataa gacaggatat
    43921 tatataggtg aagattttgc cgttttagtt ggggaatacg aaggagatag cttctcaata
    43981 ttaccacttg ctaaaaaaga taaacttcca gaagttgtag attttgtcct tgaatatttt
    44041 tctaaaaata ataaaaaaat atacttaaga ggtattacta ctgaagtagt agagttttta
    44101 aaagaaaaat atccaggtag atttgagtat atagaagaaa gagatttatt tgactatatt
    44161 tatgatgcag aaagtttaag aactctagct ggtaaaaaga atcaaaagaa gagaaaccat
    44221 ataaactatt tcttaaaaga gtatgcaggt agatatgaag ctaaattatt agataaagaa
    44281 aactttgatg agtgtttagt actaatgaag gaatgggaaa gtaataagga agaaaataat
    44341 gaatttgatg aaagtatgga tgatgaatta ataggtatca aaaagatatt taaccattat
    44401 gacatattaa aagataaggt aaaagtgttt ggtgtttatg tagatggaaa attagaagct
    44461 tttagtatag gagagctttt aaatccaaat atggcattga ttcatataga aaaagctaat
    44521 cccgatataa gaggtctgta tccatttata aatcaacaat ttttggtaag tgaatttaag
    44581 gacgttgagt ttgtaaatag agaagaagat ttaggtattg aaggattaag aaaagctaaa
    44641 ctttcttatc atccttgcag atttgttgaa aagtacagtg ttagggaggc ttaatagact
    44701 atatggagat taggtatgct aaagaagaag agatagaaag tataaaagat atttggagtt
    44761 attgttttaa cgatacggag agttttatga agtactattt taatgataaa tataaatctg
    44821 aaaatactgt agtagcttta gatgaaggaa aaattatttc ttctcttcag ctaaatcagt
    44881 ataagttatt actaaatagc aaggtatata atacatcata tgtggtagga gtttctacac
    44941 ttccagaggg aagaggagct ggatatatga acaaagtaat gaaatttact ttaaacgaat
    45001 tgtataaaaa agggcaatta gtttctatat tgatgcctat tgactataga ctttatagaa
    45061 gatttggata tgagcattgt tacgaccaga ttgaatatac tattaacaca gatgatttaa
    45121 aaaattttaa gtcaagtgga aaaatgataa agtctaattt atcacaaatt gatgatttga
    45181 tacaaataga tagaactttt ttaaatgagg ttaatggtaa tgtgttaaaa gatgaacatt
    45241 attatgaaaa cttatttaaa gagattcaaa gtgaagatgg atttttatac attcatgaag
    45301 gaaatgaaaa agatggatat atagtttatt ttcttcagga agataaaatg tttgtcagag
    45361 agttatttta taaaaatata gatgccctta aatcaatgct taaatttata tataatcaca
    45421 atactcaatg taagatagtt actatatcta ctcctacaat agataagata aggtttatat
    45481 tagacaaccc taaagatagt gatataaaaa taaaaccttt tatgatggga agagttataa
    45541 atgtaaagaa gtttattgaa gatatagata ttgagaagga tattaatagc tcatttaatt
    45601 tattaataga agacaagttt atagatgaaa ataatggtct atttaaaatt tctatacaga
    45661 ataagaaggt atctgtagag cagttagata aaaaaggtgc agaaaagcct caagaagatt
    45721 ttgatattaa attagatata aataccttaa cacagttatc attttcttat atagatgtaa
    45781 atgaagctat tttcttaaat gatataaaag atgtttcaga agaaacacta gaaacactta
    45841 attgtatttt ttctaaaaaa aataactata taaatgaata tatataggta gagtacgtta
    45901 aaagattcta aaaatctttt gacgtatttt tttgtttaga taacaattta tcttgtttaa
    45961 aaattttcta tttgaaaata atctaaataa tatactttta tatgggagtg attataattc
    46021 aaataagaag accattatta attatattaa tgtttgtggt agctatatca tttatcatta
    46081 caaataacac aaaaaacgac gaagaactta atgataagat aataactata caaggagttg
    46141 tcaaaggaaa aattgaaaag aaaagataca atcagtacaa ggtaggggtt tttctaataa
    46201 atgattatac aaaaaataaa aatttgaaga ttggtcagaa agttaatatt acaggtaaat
    46261 tcaaaagttt agataaaatg aagtatgatg attttgatta tggaaggtat ataaaaagta
    46321 ctggatataa aggtatagtg tatataaata actataaaat tattgataaa aataaacttt
    46381 actctttaat aggggaaata aagttttata ttagtaaaac ttataggtac ttatataaga
    46441 aaaactcaga ttttataaat tctatactat tagcagaagt tgaaaatttg actgaggaac
    46501 aaaaagaaat ttttaccaga actggaacta gtcatgtaat atctatatca ggtcttcata
    46561 caggaatatt atgtgtaatt atatcctttc tattaagagg tataaataaa ttgtataaat
    46621 tattaatact gtcgattttt ataactttat attgtataat ggtaggtgcg tctccatcca
    46681 taattaggtc tatagcattt gttatgattt tttatttatc aatatttatt gatagaaaga
    46741 aagatggaat atcggcattg tctctaattg ggataatttt aattatgaat aacccctatg
    46801 ttatatataa tgtaagtttt caattgtctt ttttagctac actttctata ttaatattct
    46861 ataataaaat aaatagtatt ataaaattaa gtatggtatc attgacaata tcatcaaata
    46921 tattaacttt acctataatt tattatacat ttaaaggtat accattgctt tcaattatag
    46981 gaaatttaat tatagtgcca tttgtgggag taataatgta tttaagtatt gcaagtttaa
    47041 tcgtatttaa agtaagtgta gtaatagcta aaattatatc tttttttaat agtacattta
    47101 tagaaagcat atttttttta ctagaaaaaa tcagcaattt aagttttgca tacattaata
    47161 tagaaaatcc taaattttat attgttgtta tttattacat aggagtgttt ttttacatat
    47221 tttacataga aggaaaagag ataaaggagc aagagaatga attacaagga tattataagg
    47281 aatgtaaaag agaaaaactt tgaaaaaatg tatctttttt atggaagaga gtattattta
    47341 attgagaatg caataaaagc atttaaagat agtctaaacg agggaatgct tgattttaat
    47401 ttagatataa tagatgggaa ggaaatagtc ttaaatcagc ttataagctc tatagaaaca
    47461 cttccattta tggatgatag gaagatagta ataataaaag actttgaact attaaaagga
    47521 aagaaaaaga attttacaga tagtgatgag aaatacttaa tagagcattt agacaatatt
    47581 ccagacacca caactatagt ttttgttgta tatggagatg tagacaaaag aaaatcatta
    47641 gttaagaaaa taggaaacaa tggaattgtt tttgattgtg ataagctttc tgatatggat
    47701 ttgtttaaat ggataaaaaa atcttttgct ttaaatgatg ttataataga taattctcaa
    47761 atcatgtatt ttattgaaca agaaggatac agagataaga gtagtgaaaa gacattatct
    47821 gatttagaaa atgaaataaa taaaataagt tcatttgttg gtaaagggaa taatgtaacc
    47881 aatgatgtaa ttgataaatt atctcaaaaa aaagttgaga atgatatatt caaattaatc
    47941 gattatattg gagaacaaaa tgcttctaat gcaatgaaaa tattaaatga tatgatacaa
    48001 gaaggcgaat ctgtattagg tatattttct atgatagcaa gacaatttaa aataattatg
    48061 caagtaagac agttacaact tgatggatat tcaacaaaac ttatagctga taaattaaaa
    48121 atgcatcaat ttgttgtagg aaaagcatta aagcaaacta aaaatttttc tgatgatata
    48181 attgtggaaa tattaaacta tatattagaa agtgattaca aaataaagac aggtcttata
    48241 agagatactt tagcagttga aatgttggtt agtagatact gtaaaagaga agcaatttaa
    48301 aaaatctata tattaataaa aaataaatag caagatatgt tatagttcag agtagatgta
    48361 agctaaatta agtttgatat acaatcaact ataatatgtc taactattta ttttttattg
    48421 tataaattta caaaataaaa aacccctaca taggggttat tatatataag aaatataaac
    48481 tggtaattaa gcgttcatac cgtttaattt ttgagctaat ttagctactt ttctagctgc
    48541 agcattctta tgtatagttc ctttagaagc tacttggtat attctttttt gagcgtattg
    48601 gaacttagca acagcatcct ctctgtttcc agctgcaaca gcatcttcga atcttcttat
    48661 tgcagttttt atttgagatt ttctaactct atttaaagca gttttctttt cgataacact
    48721 tattcttttc ttagctgatt ttatatttgc caccgtgttc acctccctgt atttttttat
    48781 catattcatc gtcaacatat tagattttaa cagaaataaa tctaaaaatc aaggattatt
    48841 atttatatat tttaataatg ttttttattt tgatttttta gactgtaaat tgtgtataaa
    48901 taatttgcaa tatcttgttt ttaaattggt atattttgtg ttttaaatat tttgacatat
    48961 ataattaata tttcattttg taacaaatat ttgagataat acaaactatt aacatacatt
    49021 ttgatagtat ttccaataat tataagataa tacaagaaat tactcatttt tgtaaattta
    49081 atgaaaaatt ataaaaatat aaatttatat gcttaattaa gataattttt ccaataatca
    49141 agataatttt tttcattagt atgtatgata gatgcatcaa acaatataac taatatgtta
    49201 gaaggttata tgtaattaat gtcagtgttt atatagaata gcatttgtag catttattat
    49261 agttgtaatt actatttata tcatagactt gaatagtcta aaaaaataga ctataatatt
    49321 tttatagact aaagaaaggg ctgataagat ggacatagca aaactaattt taaatcctgc
    49381 aaggcttcgt attttacaat atattcgact ttatggcagt gttcgtacat ctgatattgt
    49441 aaagtattta aatgatattc ctcgtgcaac agtttatcac catgtaaaaa ttttagaaga
    49501 gaacaatatg attgaagtaa ttaaagaaaa tcgtgtgcgt ggtactattg aaaaggttta
    49561 tgcactaaag gaatatacaa catctatgga aggagagacc ttcgttgcac tttctacagc
    49621 attttatgta ggtctgatgc aggaaatgaa tgaatacttt agcagaaaag agcaagacca
    49681 taaaaaggat aatgtatttt tctcttcagc attactatat atgagtgata atgaatatga
    49741 aaatcttctt aaaagtatag ctgatttatt gaaaccatat atagaacaaa aacctaaatc
    49801 aaatctaaaa cttagaaaac tttcaattat atcttctcca cctgtagctg ataatgataa
    49861 aacaaaataa catgcaaccc atttttataa aaggaggtta tatatgaaat ttcatgagtt
    49921 tggaaataaa aacagaccac atattatgtt gattcatggg ggagggaatg catggtggaa
    49981 ctatttgcga caagcagaag ttttgtctaa caaatatcat gtgatacttc ctacattgga
    50041 tggtcatgga gaagaatatg aaacaacata catttctaca gaggatacag cagataagtt
    50101 gatatcatat atagatgaaa attgcagtgg acatcttttc gctttgtgtg gggtatcact
    50161 tggtggtcaa attgtcatgg aacttttatc tcgaaaacct aatattacta aaaaagcaat
    50221 tattgatggt agtatttgct acccaagacc tcttatggca aggttttgta ttgctggtat
    50281 tcgatttttt ggaggacttt tgtttagtga gaaggcttgt cgctttcaaa ttgctatgat
    50341 gccaaaattg ttacctgaaa atatgcaata tccagatgaa ataaaagcgt attatatgac
    50401 agatatgcca catgtaagaa aagaaacatt ctataatatg tatcgtactt acatgatgaa
    50461 ctatacactt aaagagaatg ttaaaaaaac cacagcacaa gtaatgtact ggtatggaga
    50521 aaaagaaatg aagtgtgtca aaaaatctgc aaaactgttt cagtcttatg tgccctcttg
    50581 tgagatttat gaagctaaga gctataatca tgggtattta tcactttatc ttccaaatga
    50641 atggttggaa attgcagaac catttttcca aaaggaataa aggtgttagg tgattattgt
    50701 ataattattg ctgttttttt atatagtaaa taaattaggt ataaatataa aaaattattt
    50761 tagttaatat attagtgaaa gcttaatagg aaaattataa atagattaaa ggtagcacct
    50821 atataaatag ttgctacctt tttctgtttg taaataaatg atagataaga aggtttactg
    50881 acaaatcact gactaaaccc aattttctta cattgaaagc cttaatttta cttgttttaa
    50941 ataaatttac aatttcttgt tataaaatac taaattttgt taacaattat aattagcatt
    51001 taatttatac tggaggttta tatgattagt gtaagaacag atttagcttt agaagctagt
    51061 gaaatgtgtg aaaagtctca agaaggaagt agtattcctg gtgtaaaaat agaaactaaa
    51121 gaattagaaa attgcattgt aactaaagtt gaagtaatag acaggcaagg cgcagagata
    51181 atgaataaag atataggaaa gtatataact ctggaaagta atcttatgaa gtttgatgat
    51241 gatgagtcaa gagaagaaat gataagttat ttaaaagagg agttagtaga tatatttggc
    51301 caagacaaaa ataaaaaaac cctggtaatt ggtcttggaa atagaaatat tacttctgat
    51361 gcgttaggac caaagagtgt atcaaaaaca cttgtaacta gacatctttt taaaaattat
    51421 aataaagact atgatgatga tttcactgag gtatcagctt taagcccagg agttatgggt
    51481 gttactggaa tagaaactag tgaaatagta aaatcattgg ttgagaaggt taagccagat
    51541 agagtagtag caatagatgc attggcttca agaaaaatgg agagagtaaa ctctactata
    51601 cagatatcaa cagcaggaat atcacctggt ggaggtgttg gcaatactag aaaatctcta
    51661 actaaagaaa ctttaggcgt ggatgttatt gcaataggcg ttccaacggt ggttgatgca
    51721 gcaactctta caatagatgt cttagatatg gcaatagaca atttaatagc tcaatcagaa
    51781 gaaacagaaa gtttttatga aatgttgaaa aaacttaaag aagaagaaaa atatcatcta
    51841 ataaaagatt cgttagaccc atatgacaag aacttaatag taacaccaaa ggatatagat
    51901 gatacaatcg aaaatctatc tataataata agtgaaggct taaataggtc tttacatcca
    51961 ggtagattgg tataaaataa ggaggagcaa ttatgtttaa aaaatgcatt aaagtagtaa
    52021 ccttgacttt tatattagta tgcattttac caggaaaatc attagctttg aatcaagatg
    52081 attttttaaa gtttttagta aattcatctt atccagaagc taaagtcgaa ggaaatgata
    52141 cagaaaataa aaagaataat aaaaataaag aaacaagtaa ggaaaataag gaagaaagta
    52201 aagaaggaaa cactaaatct aaagatgcaa gtaaagttga taataaaaaa gagagtgaaa
    52261 aagaatatat aaaactttat gttggtaaag aaaatgttcc agatattgag tcaaaaaatt
    52321 cagacacaac tgaaactaac acaacatcta gttcagatta taaggatgat ttaagagtaa
    52381 ccaaagaaaa tccaagaatt ttgatatatc atactcatgg atgtgagact tattcaaatt
    52441 cacctgatgg aaattatcat tcaagagata agaaaaattc agtaatggaa gtaggaagtg
    52501 cattaactag tgctttagat agcaaaggat ggggtgtagt ccatactact aaataccatg
    52561 actatccatc ttataataac tcttatgcaa gtagcttaaa aacaatacaa agtatattac
    52621 ctaaatataa ctcagtggat atagcgatag acttacatag agatgctagg gatttaacta
    52681 atccagccac taaggaaaaa gaccatttaa aatatacaac tatgataaat ggagagagag
    52741 tatcaaagtt cttctttgtt gtaggaggta aaaatacaaa tagaaaacaa cttagagctt
    52801 tagcagaaga tataactgct tttgctgaga aaaagtatcc tggtctagta tctccaatag
    52861 tagaaaaaga ctatgctaga ttcaatcagt ttgcagttaa gaatcatatg ttagtagaaa
    52921 tagggaataa cgcaacaagt gtagaagaat ctaaggctac tacaaagtat ttagccgaga
    52981 ttttggatga atattttaaa caaaaaaatt agagctttaa gttataatta ggagcatgct
    53041 aaatgagccg attagaaaaa aatatagaaa gtaaaagtaa actaagaaaa tacaagtata
    53101 ttatgagaat cttatttttg attactatga ttatatgtac atcagtttgt gtatttatag
    53161 tggacagtaa tgcaaaaagt atgctaggaa tgaaacaata tgattttcca agtattaaat
    53221 ttgatataac aaaatttgat tttgacatac caaattttga tatacatgaa atcataaaaa
    53281 aatttaataa gtagtaataa gtgaataagg tttattgatt aaaataagcc ttattttagt
    53341 tatatatttt taatgtataa aataaaaatt cattaactgt attttatagg atttacttta
    53401 agtttatgat attatataat atttagtgtt agacttgata atccacatat aatgtggata
    53461 attttgttta gtgccaatta gtttatattc aaaaatttta aatttggtat ataaagagtt
    53521 tttagataat gtaaaataat aactataaga ataatcaaga ggagggaatt ttaaggtgga
    53581 caataaacaa agtagaacta gaaattttag tataattgca catatagacc atggaaagtc
    53641 taccttagct gatagattaa tacaacaaac tgggcttgtt agtgaaagag acatgaaaag
    53701 tcaattactt gacaatatgg accttgaaag agaaagagga atcactataa agcttcaaaa
    53761 cataagatta atgtataaag cgaaggatgg aaatgaatat tatttaaatc ttatagatac
    53821 acctggacat gtagacttta actatgaggt atcaagaagt ttagctgcat gtgaaggagc
    53881 actattagta gttgatgcag ctcaaggtgt tgaggcacaa actttagcca atgtttatct
    53941 tgctatagac caagatttag aaatattacc aataataaat aaaatagatt taccaagtgc
    54001 aagaccagag gaagtaaaaa atgaaataga agatttaata gggcttgatt caagtgaagc
    54061 tcctcttatt tcagctaaaa ctggtttaaa catagaagat gttttagaag atattgtaaa
    54121 aaatgttcct ccacctaaag gagataatga agctccatta aaggcattaa tattcgattc
    54181 ttactatgat gcttacaaag gtgttgtagc ttatgttaga gtatttgaag gaactgttaa
    54241 aaagggtatg acaataaaaa tgatgaatac caataaaaag tttgaggtaa ctgaagttgg
    54301 tgttatggct ccaggtcaaa ctgaacttag tgaattatca gcaggtgatg ttggttatat
    54361 tgctgctagt ataaaagata taagaagttg tcgtgttggt gatacaataa cagattcaaa
    54421 taatcctaca gaagaacctt taccaggata caaaaaagct actccaatgg tatattgtgg
    54481 tatatatcca ggagaaggag aaaagtatga gaatgttaga gatgctcttg aaaagcttca
    54541 agtaaatgat gctgcacttg aatatgaagc tgagacttca gcagcactag gatttggttt
    54601 tagatgtggt ttcttaggtc ttttacatat ggagataatg caagaaagac ttgagagaga
    54661 atttaacctt gatataatta ctacagctcc atctgttata tatagagtta caaaaatgga
    54721 tggagaggtt gtaatgatac aaaatcctgc aaacttacca gaaccatctg agataaagat
    54781 gatagaagag cctatagtaa aaggagatat aatagttcct aaagactatg tgggtgttgt
    54841 tatggagctt tgccaggaaa gacgtggaaa tatgttaaat atggaatata tagatgatag
    54901 aagagtaatg cttcactatg accttcctct caatgaagtt gtttacgatt tctttgatgc
    54961 tttaaaatca agaactagag gttatggttc tcttgattat gaggttaaag gttatgtagc
    55021 atctacactt gtaaaacttg atatattaat caataaagag caagtggatg cacttagttt
    55081 tattgtccat gagacacgtg ctttccctag aggaaaggca atgtgtgaga aattaaaagg
    55141 agaaattcca agacatcagt ttgctatacc aatacaagct gctgttggta ataaggttat
    55201 tgcaagagaa acaataagcg ctctaagaaa agatgttctt gctaaatgtt atggtggaga
    55261 tatatctcgt aagaagaaac ttcttgaaaa acaaaaagaa ggtaagaagc gtatgagaca
    55321 aattggttct gttgaagttc ctcaaaaagc atttatgtct gtgcttaaat tagatgagta
    55381 aatccttata aatttagata aagatattta aaagctagag tgattttaga attatttcta
    55441 aattagtcta gcttttttat ggtatatttt aagtaaactc atagagaata taagtaagaa
    55501 tattaaagaa gaataaaaag gtgatattta tgattaatat agaaattcct aaaaaagtag
    55561 actatataat taaagaatta gaaaagaatg gttatgaagc ttatatagtt ggaggatgtg
    55621 ttagagattg tttattagaa agagttccaa acgattggga tataacaact agtgctagac
    55681 cagaagtggt agtagaatta tttgaaaaaa caattccaac tggtatacaa catgggactg
    55741 taacagttat gattgaacat gaaccatttg aagtgacgac ttatagaatt gatggaaatt
    55801 atagtgatgg tagacatcca gattcaatag aatttacaaa taacatagtt aaggacttgt
    55861 caagaagaga ttttactatc aattcaattg catacaattc aaagacagga ttagtcgacc
    55921 catttaatgg ctatgaagat atacaaaata agtatatacg ttgtgttgga aatccagtag
    55981 atagatttga agaagatgca cttagaatgc ttagagcagt tagattttca gcacaactca
    56041 attttaaaat agctgaaggt actaagcaaa gtattcataa aaaagcagat ttgataaaaa
    56101 atgtttctat tgaaagaatc cagacagagt ttaataaaat attagtatct gattcatcta
    56161 aattaaactt attaaaatca acaggtttgt tgaaatttat aattcctgaa atatgtgaat
    56221 tagaagatgt tactcaacac aatccatatc acatctatga tgtacaaaaa catactttaa
    56281 tagctacaga agtaattgaa gatgaactgt atttaaaact tacaatgttg tttcatgatt
    56341 taggtaaaaa agtaactaaa acaactgata aaaatggtgt tgaccatttt tatactcata
    56401 gtagagaatc tgtaaagatt gcaaagaaga ttttgaaaag acttaagtat gataattata
    56461 ctattaataa agttttaata ttaatacaat atcatgatta tagaatagaa cctaaaagga
    56521 agataattaa aaagttatta aataaacttg aagatgttga attatttgaa gatttaataa
    56581 aagttaattg ggctgataca cttgcaaaaa atccaaagta tgcaaaacaa aagatattaa
    56641 atcttattga gtgtgaaaaa gaatttaaac atataataaa tcaaaaggag tgctttaatc
    56701 ttaaagattt agctattaat ggaaaagatt tgatatctat aggtataaaa ccaggtaaag
    56761 atataggata tattttaaat aagatgcttg aaatagtcat aaataatcca gagttaaatg
    56821 aaaaagaaat actaaaagaa aaagcattaa atatatatac attttagatt caaatataaa
    56881 aaatttaatt actttaaaaa acatagaata aaatacttat ttagataaaa taaataattt
    56941 ttagagaata ttttagaagt tacgattgta tgatttttaa atgcataggc atttactcta
    57001 ggactataga ctaatataaa aaaaaacttt gggaatacta aaaccataaa tttataaaat
    57061 taatatttta tatactgtaa aacagtgagg agggacagta tgcatactca actacaaaag
    57121 actattggtc tttcagcagc tctttctact gttgtaggta tggttatagg ttcgggagtt
    57181 ttttttaagc cacaagcaat atacactaca actaatggag ctccaggtct aggtattata
    57241 gcgtggcttt taggtggttt tataacaata actgctgggc ttacagctac agaaatttca
    57301 gctgctatac caaaaactgg tggtatgatg atttatatcg aagaaatata tggagaaaag
    57361 ttaggttttt taactggatg gatgcaaact gtattatttt tcccaggtac atcagcggca
    57421 ttaggagtaa tatttgctca acaagcatct gaacttttag gaatgagccc aaataatatg
    57481 gcaaatgtac ttcctatagc aattggagtt atactatttt tagcgttatt aaatataata
    57541 ggttcatcct taggaggaaa agttcagaca gtagccacta ttggaaagat gataccttta
    57601 attttaataa tagtctttgg atttattaaa ggtcaaagta gtgaagtatt aaatccattt
    57661 gtaggagatg gtgtaaatgc atcaaatgca cttggacaag tattaatagc tactttgttt
    57721 gcatatgatg gttggataaa tgttggagct atatcaggag aaatgaagtc tccagagaaa
    57781 gatttaccaa gagcaatagt tggtggttta tcattagtta tggcagttta tattataata
    57841 aatatagctt atctttgggt agtaccagca agtgaattag caacagttac ttccccagct
    57901 acattagtag caacaagatt gtttggaaat ataggtggaa aagtaataac tgtgggtata
    57961 ttaatatcag tatttgggac attgaatgga tatttattaa caggttcaag gataccttat
    58021 acattagctg aaatgggaac tttaccagca tctaaaactc ttttaaaagt aaattctgga
    58081 ggttctcctg taaattcaat actacttata actgtgttag cctgtgtata tgcattatct
    58141 ggtcaattta atcttttgac agacttaaca atattttcaa tatgggtatt ttatgtattg
    58201 acttttatag gtgttatgag gcttagaaga caaaagccag atttacacag accatataaa
    58261 gtccctttat atccaataat accaattata gctatattag gtggactgtt tgtaataata
    58321 aatcaaatat tgacttcaac agtcatatct ttaggcggaa tatttataac actattaggt
    58381 ttaccagttt attattatat gaaaaaaaga taactactta atttaagtta gataaatttg
    58441 ggtaaaggtg aaaattaact tttatccaaa ttttttatac tgttatacaa tataagtatt
    58501 atatattgct tgatgtgcta ttttgtttga tttataattt agtaattgat gttttaagat
    58561 aatttaagaa atgaggagtg aaagatgcta ggactttatg tacatattcc attttgtgtg
    58621 aaaaaatgta agtattgtga ttttaattct tataaaatgg acatagattc aaaaaaaaga
    58681 tatatagaag acttaaaaat agaaatggaa ttatatagta ataaattata taaagataat
    58741 aaatataaaa ataaagaatg ctgtagtcta aataaaaatg acaaaataac gagtatattt
    58801 gtagggggag gtacacctag tatactaacc tctgatgaaa taagagaagt atttataagt
    58861 ataaaagaaa tgtttgatat agatgagaat gcagaaataa ctatagagtg taatcctggg
    58921 acattaacat tagaaaaatt aaaaactatg aaagagattg gcataaatag acttagtata
    58981 gggctacaag ctattcaaga aaagcatttg aactttatag gaagaataca tacttatgaa
    59041 gaatttgaga aaaactataa agatgcatta agtgtaggtt ttaaaaatat taatatagat
    59101 ttaatgtaca gtcttccaaa tcaaactcta tgtgattgga aggaaactct tgaaaaagtt
    59161 gtacacttaa atccaacaca tatatcagct tattccctta tactagaaga aggaactgaa
    59221 ctatacaata tgtatgaaag taataaattt gaacttatag atgaaaatgt agatatagaa
    59281 atgtatgagt atacaataaa ctacttaaag tcaaaaggat ataatcaata tgaaatatcc
    59341 aactactcaa aagaaggcta taattgtgag cataatattt tatattggga atgtgaacat
    59401 tatataggga ttggagcagg agcttctggc tatattaatg agaacagata caataatgta
    59461 gaatctttag aagattatca tttaagtttg gtaaaaagag aaaaaccaat acaagaaaat
    59521 gaaattcttt ctgagaaaga tatgatagaa gaaaagatat ttatggggct tagaatgaat
    59581 aaaggcataa aatttgaaga ttttaaaaaa aaatttggaa tagattttag agagaagtat
    59641 aataagcaaa tagaaatgct attagctaga aagcttataa atcagagctt tgaaggtata
    59701 caattaactc aaaaaggaag agaaatatct aatagtgtat ttatagaatt tatggaataa
    59761 tttttaaggt gttgacaaaa taaatttata atggtatata atatatataa tctttttagc
    59821 actcgaactt agtgagtgct aacagctagg aggtataata atatggaatt aaatgaaaga
    59881 aaattaaata tcctcaaagc tatagttaaa gattatatag aaacagctga agctataggt
    59941 tctagaacaa tatctaaaag acatgattta ggtgttagtg ctgctaccat aagaaatgaa
    60001 atggctgacc ttgaagaatt agggtattta attcagcctc atacttctgc gggtagagtt
    60061 ccatctgaaa aaggctataa gttatatgta aactctctta tgagtaaaag cgaattggat
    60121 gataatgata agattcttat tgaacaatgt atgaatcaca atataaatca tataaaagaa
    60181 ttgattcatg aaacttctaa gctattatcg caactaacaa actatacaac tgtagcagtt
    60241 actaagagtt taataaatca aagtgttata aagcacatac agttggttgc tatgaatgac
    60301 aataatattt tacttatagt tgtaacagat aaaggggact taaaaaaagc taaccttaca
    60361 actaatgtat atttagatca atctaagtta aatttgattt ctgataatct tacaaggaag
    60421 ctcttaggta aaagtataac agatttggat gataatctaa ttgcttttat taaatacgaa
    60481 ataagtgagt attctgggct tatagatgag cttttaaatg ctttgaactc aaatatgaaa
    60541 gaagaagatt tttctctatc attaaatgga gctactaaca tatttagtta tccagaattt
    60601 aatgatgtat taaaagcaaa gtcattttta aatatgttgg aaaaaaagga aacaatagct
    60661 gacataatta aatcaaaggg aatacaaaaa gacaatctaa atataataat tggtagtgat
    60721 aatgattgtg aactggcaca ggattgtagt atagttacag caacttataa tgtagataga
    60781 gacttggttg ggcgaataag ctttataggc cctaccagaa tggattatgc tagaatttac
    60841 tctataataa attatatgag tttattaatt aatagaaagt aaagaaattt taaattgcga
    60901 ggtgtaaagt cttggataaa aaaaatgagc aacaggaagt aagagaagaa aatgatactt
    60961 ctattaacca agaatcggaa actcaagtag agttagaaga ggaagttgtt aatgaagaat
    61021 gtgaaacatc aagtgaaaaa actgatgaaa aagaagttga tgatgaaaat gtaacagata
    61081 taaattctaa gttagcagaa aaaaaattgc aggatgagtt ggatgaatta aatgataaat
    61141 atcaaagact tcaagccgaa tatgcaaact acagaagaag aactcaacaa gagaaagaga
    61201 caataggcgt atttgcaaat gaaaaaataa taactgaatt gataccagtt atagatagta
    61261 tggaaagagc cttagatgca tgtgaagata aggaagatac tatgtataag ggtataagcc
    61321 ttgtacataa acaattaata gacactttag taaaatttgg agtagaagaa atagaagcag
    61381 aatctaagga atttgaccct aatctacatc tagcagttat gcaagaaagt gtagatggag
    61441 ttgaagcaaa tcaaatagta atggtacttc aaaaaggata taagctagga actaaagttg
    61501 taagaccttc aatggttaaa gtttcttgct aagtataaat taaaggttaa attatttaac
    61561 ctaatataaa atattaaaat aagtaaaact taattatata attactcgag gaggatttta
    61621 gtcatgggaa aaataatagg aatagattta ggaacaacaa attcatgtgt tgcagtgtta
    61681 gaaggtggag aagcacaaat aatagcaaat agtgaaggta tgagaactac tccatcagta
    61741 gtagcattta caaaagatgg tgaaagaata gttggagaac ctgcaaaaag acaagcagtt
    61801 acaaatgcag ataaaacaat aacttctata aaaactcata tgggaactga ttataaagta
    61861 aatatagatg gaaaatcata tactccacaa gaaatatcag caataatatt acaaaaatta
    61921 aaatcagatg cagaaagtta cttaggacaa acagtaacag aagcagttat aacagtacca
    61981 gcttacttta cagatgctca aagacaagca actaaagatg ctggtagaat agcagggctt
    62041 gatgttaaga gaataataaa tgagccaaca gcagcagctc ttgcttatgg tatggataaa
    62101 ttagaccaag aaaagaaaat attagtattt gacttaggtg gaggaacttt tgacgtatct
    62161 atacttgaaa taggagatgg aacttttgaa gttttagcta cagctggtaa caatagatta
    62221 ggtggagatg actttgacca aatagtaata gattatttag cagaggaatt taaaaaagct
    62281 gaaggtgtag atttaagaaa tgataaaatg gctcttcaaa gattaaaaga agcagcagaa
    62341 aaggctaaga aagaattatc atcaacaatg agttcaaaca taaacttacc tttcataact
    62401 gctacagcag aaggaccaaa acacttaaat atagatttat caagagctaa atttgaagaa
    62461 ttaactagag gtttagttga aaaaactatg gaaccaacta agacagcttt acaagatgca
    62521 ggactttcta caggtgatat agatgatgta ttattagtag gtggttctac aagaatacca
    62581 gcagtacaag aagctgttaa gaagtttata ggaaaagaac ctcataaagg tataaaccca
    62641 gatgagtgtg ttgcagcagg tgcttctata caagctggag ttttagcagg ggatgttaaa
    62701 gacttattat tactagatgt tactccatta tctcttggta tagaaactat gggtaatgta
    62761 atgactaaga taatagaaag aaatactaca ataccaacta agaagtctca aatattctca
    62821 actgctgctg ataaccaaac agctgttgat atacatgttc ttcaaggtga aagaagtatg
    62881 gcttatgaca atacaacttt aggaagattc caattaacag atataccacc agcacaaaga
    62941 ggaatacctc aaatagaagt tacttttgat atagatgcaa atggtatagt taatgtttca
    63001 gctaaagatt taggtacagg aaaagagcaa aaaataacta taacatcaaa cactaattta
    63061 tcagaatcag aaatagagca aaagataaaa gaagcagaaa tgaatgcaga agctgacaaa
    63121 caaaagaaag aaaaaataga agcattcaat caagctgaat ctactatata tcaaactgaa
    63181 aaaactttaa atgaacttgg agataaaata agttcaggtg aaaaagagga tatagaaaaa
    63241 gctatagcag acttaaaagc tgtaaaagat aatcaagatg ctacagcaga agaacttaag
    63301 aaagctacag atgaagtaat gactaagttc caaaaagtat ctcaagaaat gtaccaaaaa
    63361 gcagctcaag aacaacaagc ggcacaaggt gcagaacaag cacaagacaa tggacctaaa
    63421 gatgacaatg tagtagatgc tgactttaaa gaagtagatg aagataaata agctatataa
    63481 tatgtaacac taaatgataa ttggaacata tatgatttgt gaaaatcata tagatgttaa
    63541 agatatatgg acaatataca tcataaagaa tataatatat catagattat ataacttaaa
    63601 gtagaatata agaattaatg atagcttgta gtttattatt ctacaagcta tcgttttgta
    63661 aaatgaaggt ggtgtcaatt tttgagtaca aaaagggatt attatgaagt cttaggtatc
    63721 agtaaaggtg cagaagctca agagataaaa aaagcttata gaaaattagc aatgaagtac
    63781 catccagata gaaatcctgg agataaagag gcggaagaaa aatttaaaga gataaatgaa
    63841 gcttatgaag ttctatctga tgatacaaag agaaaaactt atgaccagtt tggacatgat
    63901 gggctaaatg gtcaaggcgg ttttggtggt caaggaggat ttggcggtca aggctttggt
    63961 ggttttgaag atatgttcgg agatatattt ggtgacatgt ttggaggaag cttcggaggt
    64021 ggaagagcaa gaagaagagg gcctcaacgt ggtgcagata taagacagag tgttactata
    64081 tcttttgaag aagctgcatt tggtaaaaag atgtctataa aagtaaatag aagtgaagaa
    64141 tgtgaagaat gtaatggaac tggagcaaaa ccaggaacat caaagaaaac ttgttcaact
    64201 tgtaatggaa ctggtcaagt tagaactgtt caaagaactc catttggtaa tatagcaagt
    64261 tcaagaccat gtagtgcttg taatggaact ggagaagtga ttgaatctcc atgtagtaaa
    64321 tgtcatggaa ctggaaatac aagaaaagtt aagactatag aagtagatat acctgctggt
    64381 atagatgatg gtcaaatgat aaaactttct ggtcaaggtg aagtaggaga aaaaggtgct
    64441 ccaagaggag acttatatat tgtagttaat gttaagtcac atccactatt tactagagat
    64501 ggaaatgata tttattttga aatgccaatt acatttgttc aagcaacttt aggtgatgag
    64561 atagaagtac ctactttgga tggaaaagtt aaatatagtg tgccagaggg gacacaaact
    64621 ggaactgtat ttagacttaa agagaaagga atccctagaa ttagaggtaa ttcaagagga
    64681 gaccaatatg ttaaggttgt agttgaaatt cctaaaaaat taaacgataa gcaaaaagaa
    64741 ctattgagag aatttgcgaa ggagtgtggg tcgaacgtcc acgaaaagaa gaaaaccttc
    64801 ggacaaaaga tagaagatat gtttaagaaa aagtagttaa agtagccaat atataatcat
    64861 atttttaaaa tcttagttat ttataagatt gtcaaaggag atattatgat ttttatattg
    64921 gctatttttg tataaaaaat aaatgtgcat aaaataaaac tgaatataaa taattttctg
    64981 aaaaatactt gtcctaaaat atataatatg ctataatata atcaaataaa agaaaggggt
    65041 gattccagtg ggaacggatg tggcactgcc aaatgatgaa gaaaacttta ttgtaatata
    65101 caaaataaaa ttagatactt ttagtgctag attaagtact ggaaaaactc atgagctggg
    65161 ataattattg taattaccta gactcaaact tttagtagta aaatagtaat attatataga
    65221 caaggtatct aatttttaaa tcttttgtat gaattaaaat ttttataaag ggtatatctg
    65281 attagaatgt aattagggaa acctagttgt gaattacttt tagtatatac atgtgtaaag
    65341 aaatatgtat atggtattgg gtattgtgct agatgtgtat gtaaaggaat atgtgtctag
    65401 ttgggtatat gtaaagaaat atacttataa tctatgaaaa atttttagta taaattgcta
    65461 aaacattgag attgtttttt atagaaagtt agtttatacc aactaaaaat gtgcttaaga
    65521 tttgtttgat gtttaattat aaataaggtt gtagataaaa aaataagtaa agacaaaggt
    65581 ttaaaatact tgctttaaat atagtttgtt ttgaacactt gccaaattaa aataattaat
    65641 aaaatagaca tcttctcata gtaaaatata ctgtgagagg atgtttttgc tttgttcata
    65701 aacttttatg aaaaatttgc atagtgtcac attttaatat actatatata taataaaata
    65761 tagataaaat taaatgattc aaaagagaaa ggtgaaaaga gatgtattat ataggtgtag
    65821 acataggagg aacaggtata caagcaggag tagttgataa ctatgggaag ataattttta
    65881 ggtcagagtg taaaacagta attgaaaaag gatttgaagg aatacttaat gacataaaaa
    65941 taatgattta taagttgttg gaagataata aacttactat gagtgacata aaatctattg
    66001 gatttggtgt tccaggtttt ataaataaag aaggattagt aacttgtgta aatttaaaat
    66061 ggaataaaaa agcttttaat aaagagttaa aaagaagatt tccagatgtt gaaattcatg
    66121 gagaaaatga tgcaacagta gcagcacttg gagaagcaaa gtttggaagt atgaaaggtg
    66181 ctaatgttgg agtattatat actttaggaa ctggtgtagg tggaggaata gtaattaatc
    66241 aaaaagtctt ttctggagca catggattgg gttcagaaat aggtcatcaa attataggag
    66301 aaaactattt taattgtaat tgtggaaata atggttgtgt agaaactttt tgttcagcaa
    66361 ctgcaattat aaagtattct caaaaactga tagaagaagg agaaaagagt aggattttag
    66421 atttggcaga gggaaattta gaaaatgtaa atgcaaagat ggtgtttgat gcatatagag
    66481 aaaatgattt agtggcaatt aaagtaataa atagatttaa agagtattta gcaaaaactt
    66541 ttgcaaacac aataaattct ttagacccag aaattatatc tataggagga ggcatttcta
    66601 aatctagcga tataatactt gatggaatag aaggtttggt aagaaaattt gtattataca
    66661 aaacagaaga tatagctaca attacatgtg caactttagg ttcagacgca ggaattatag
    66721 gagcagcttt tttataatgt aaatgaactg cttattggag gcgtgatgat atatgggtaa
    66781 aacaaatgct agaagaacgc tttttttgat agcaataggt tcaggaacta tgctgaatcc
    66841 tcttaattct tctatgattt cacttgcttt acatagtata caaaatgatt ttcatattag
    66901 ttttacaact gtatcttgga ttgtttcagc attttaccta gctagtgcta ttgcacaacc
    66961 agtttcaggt aagataggag atttaatagg tagaaaggtc ttatttttga gtggtttgat
    67021 gcttgtaatt ttatcagcat ccatagtacc acttgttcaa tcattcttta tattgatttt
    67081 tataagagta attcaagcaa ttggaacaag taccctatat ccatctggag ttgctcttat
    67141 acaaaataat ataaaagaaa gacaatcttc tgcattagca gttctaacca tttttgcttc
    67201 aactacagca ggattaggtc cgacacttgg aggattattg ttggacttag gaggatggca
    67261 tgctatattt cttgtaaata tacctgttgt tttggtttct atatgcttag ggtatttttt
    67321 attcccaaaa gaagtaaaag aaaagaaatc tataaaagaa actttaaaaa atgttttgtc
    67381 aagattagat attattggca tacttctatt ttcaattgca atgattttta tattactatt
    67441 tttgctatct atgaaggaat cttttaactt agaacaactt gtatttggta taatactgat
    67501 gtgtcttttt atttggcatg aattgagaac aaaattgcca tttatagata ttaagctttt
    67561 tgtaagtaat cctaaattgt caaaagttta cttgcaattt attatattaa atttctttaa
    67621 ttatattttg ttttttggtc ttcctagtta ttttcaagat gccttacatt atagtgcaaa
    67681 gtcgactgga ttatttatgc tatttatgtc tggtataggt atatttatat ctccattaac
    67741 tggaaaatgg atagataaat ctggaactag atttcctctt gttacatcat caatctttat
    67801 gtttattagt gcagtacttc tttcagtagt ttttatccat atacctgtaa taggaaaggg
    67861 tattatatta tcattagcag gtattagtta tggagttggt aatgtagccc tgcaatcctc
    67921 tatgtttgaa gaaagtcctc gtgacagtat agggacagct tctggtctgt ttcaaactag
    67981 tcgttattta ggttctattt tagcaactgt tttacttgga atggtatttg aagtaaatat
    68041 aacatcagaa caatttcaga tattaggtta tgttatggtg gtcttaggta caataagttt
    68101 tttattaaat tttatattaa agaaagaatt aagaaaagta gaatagtgga tttatggatt
    68161 taataagtct aataactgat aagtttaaaa atattgtttg taaaacataa ctggtttgat
    68221 atttattaat tctaagtttt gaagcataga gtactcgata agtatacaat attttgaatt
    68281 aaaattaagc agaaatttga actagtcttt caaatctctg cttaatttag tagttaaatt
    68341 tttttataga gaaaataaga tttgacactt agataaaaaa tcattgcatt ttcaaaattc
    68401 tttaaatcaa acccaagtat ctcattaatc ttttccaatc tatatactag cgtgtttcta
    68461 tgtaaaaaca tactagtaga tgtcttagaa atatttaaat cattatttat aaattttatt
    68521 cctgtatata gaagttcttc gtcaatagat ttaatcttat taaaatctat taatttattg
    68581 agtatattat cctcattaat taaatctaaa gttttatatc taataaggtc aaacaaattt
    68641 aaaaacttat tttcagcgtt gtcttttata atatgaggta gtaaatcaga acataactgt
    68701 aatctaaaat caaaatcagc tttactatct aattcaccaa gataaaaaat ataagtactt
    68761 tgataagttt cagtttcaat tatattttgt gtagttacat taatatctaa gttatattta
    68821 gaatttacta taaaaaaacc attgtgttgt attatattta tatcttcaaa taaattataa
    68881 aaaatatttt ttagatattc aaagtctata tgagattggt aaattaaata aaagttgcct
    68941 tttaaattat cgagattatt tttatctaga aaatcaataa cataaatagc attattgaaa
    69001 gtaactaaat ggctactagc atctaacttt tggttttcat atggatagat atttattttt
    69061 ttattaagct gtctttctaa aaaatctttt aactcttcca taaagtctcc ttaaaaataa
    69121 gattatattc ttatcttata gctaaagtag tttctttgtc aaatatgtgt actctactat
    69181 tgtcaactga aagtgttaag tcatcaccaa cattaattct gtttttactg tcaaatctaa
    69241 ttgttatcgt attttcgcct agttttaagt gagcataagt ttctgctccc ataagttctt
    69301 ttatttcaat tcttgattta aaacaagtat ctggattaga tttaataaaa gtatcttcta
    69361 catgaatatc ttctggtctg atacctataa caacttcatt attaatataa ttgtctttta
    69421 ttaaatcata gtgtttttct ttattcaatt taagcttaat atgttcattt tgtgcataaa
    69481 tttcatcatt ttcttctatt aatattacat caataaaatt catctgtggt gctccaataa
    69541 atcctgcaac aaatatatta gctggataat cgtatacatc ttgtggagtt gcaatctgct
    69601 gaactactcc atccttcatt actacgattc tatcagccat agtcatagct tcaacttggt
    69661 cgtgtgttac atagataaat gtagttccaa gctgttggtg tagcttagtt atctctgttc
    69721 tcatagcagt tctaagtttt gcatctaagt tggatagagg ttcatccatt aagaatacct
    69781 taggatttct aactattgca cgtcctaagg caaccctttg tctttgtcct ccagataatg
    69841 ttttaggttt tttatttaaa agaggtagta agtctaatat tttagcagct tctttaactt
    69901 ttttgtctat ttcatcttta ggcaattttc taagtttaag tgcaaatgcc atgttttcgt
    69961 aaacagataa gtggggatat aaagcatagt tttgaaaaac catagctata tctctatctt
    70021 ttggttctat atcattgaca agtttatctc caatgtatag ttctccttca gagatttctt
    70081 caagaccagc aatcattcta agtgtagtcg atttaccaca accagatggt cctactaaaa
    70141 cgataaattc tttatcttta atgtctatat ttatattttt tactgcatta aatccatttg
    70201 agtaaagttt tgatatattt tttaaaatta cttctgacat aatatcctcc ttgatattta
    70261 aattttaatt atatagtatc aaattttttt attatattaa atgtgtaaaa tgactaaatg
    70321 tatttgttta atatgtatag ttagttttta tattaagatt tattataatt tagaaaatat
    70381 attttaattt ttttaatttt tatgtataat aatatatata ttttttagat taacaatatg
    70441 ggatttaaat tattttttaa tttataatga aataatatta tattagtagt tttggttaac
    70501 aatgaggagt ttataaataa ggtcatataa gttaaattat atcgatttta tttaaataac
    70561 cccatattta ttaattatta gaaatatatt ttaattattg actaaataat aaatactgta
    70621 atataatgga aatacagttt aataaatata aaaagagaaa gagggaattt taaatgaatt
    70681 tgaagaaaaa agagaaaata gttaagcctg ttttaaagaa gcttacagaa atagtattaa
    70741 atatattatc aaaaaaaata ttaaactatg ctatatatgc aatttctgtt ttgatagtaa
    70801 caaaagttgt tataaatata gatttgtaca tatccatatt gtattattag atatcttata
    70861 gatataaaaa attaatagat atatatctat taatttttta tattacaaat agagaataat
    70921 gaattatact agaaagtagg aggtgaaaat atgagcagaa tttcaatttt tatggaatca
    70981 tgtaatggca aatttccaaa tgaaaattca atgttgtcag tttcctttat aaaaaatatt
    71041 ttaaatgcag aaaacaaaga ttttgctaaa aacatattta actatgggga agaaagaaaa
    71101 aacaataagc aaataaagga tataaataca gccatttaca taccaaatct tataagaagc
    71161 aaaaatgagt tacttgttga tggagatata atattcaata taagttttta taattattct
    71221 atgttcagta aattatacaa tggaatttta aaagtaaagg agctagaata taaaggttat
    71281 agatttaaaa taaaaaatat aaaaatacat aaagaacacg agataaaaga aaatggtgtt
    71341 atatttaaaa ctatgtctcc tataatagta aagaataaag aaggtaaata tttagatgta
    71401 gaagattcaa attatataga atgtttaaac tatatagcta atctaactct ggagagtata
    71461 agaggtagtg ggcttagaaa gccattggaa tttatacctc ttaacttcaa aaaaagagtg
    71521 ttaaaagaaa agattcgtgg atttaaagag agagaatttt actatataaa tgcttatgca
    71581 ggaacatttt ttttaaaagg aaatatggaa gatttaaatg cactgtataa aatgggaatt
    71641 ggatatagaa ggacggaaaa tgcaggaatg gttgatatat taaagtagcg aggtgagaga
    71701 aataaaagct aaattttata gatcaggtga tattgtaaga gatattggca ttgtttactt
    71761 ttgtgaatta ctaatggatt taaaaaacga actagaaaaa aatgattata agctaaaatt
    71821 tacttgtgag ttgaatagaa attatttatc tttagaatct gcagaatata tagaccctaa
    71881 gtatatatct gattatatat tagaaaatca actttttaag gtatttaaaa atgggaaaaa
    71941 ggaaacctta gaaaaaatat ttagtaatat agataattta acatatgtaa attttattga
    72001 agaattggat aaatcttctg caactgagaa acaaaaggaa gggattaaaa aagattttaa
    72061 aaacagaaga tttccatatg ttagaaatag tggtaagtat ggattaaaca cgagtctaga
    72121 aaatatggaa aaaaatgtaa aaagaatagt cgatattgtg attaaatcaa atatagagat
    72181 agatgaaata gataaacttg atttgaaaca atatgaagaa aaagatagtg tatgtaatgt
    72241 ttgcaatata aataaaacaa caaaactaga tattgattta agagaacgaa aggactctaa
    72301 gtataacttt ttatttagag gtgcagaaaa atcaggtttt aaaagaagtg gacaagttga
    72361 aagtaatatt tgttttgagt gtgaattttt caacttaatg tgtcttttat atataaattt
    72421 aaaaagacca atggtttttg catatacgaa tgatttaaga gaattagcat ttttaaatca
    72481 taagataatg cttaaaagaa aaatgtattc agataaatca ttttataaaa aacttttgca
    72541 tgaaaaaata agttcaatta gactatatag gattgatatt gatacgaata aaggtataat
    72601 tctaaaattt gactctatta tagagtataa agaattatta aaaaaaattg aacttataga
    72661 tattatagat aattataatt tttcaagaga gccaatgaat actagaaatt tgggtaaaaa
    72721 aatgattaat aatgggaatt tatcaaattt aaaagaatta ttacttgata atataagtgt
    72781 tttaaggcaa ctaactggaa cttctcgaga aatggatttt gtatctagtt catataatat
    72841 cggtttatat ataaaattgt gttggattgt agatggaagg gaggagtata aaatgaaaaa
    72901 ctatatagaa agtaatttaa tatattcaag agtaggtaaa gacttattta ataaaatgac
    72961 agatgaatcc agaagaaaaa atttttctat gaaagtgatt caactactta agtctaatga
    73021 tagaactcag ctatttcaaa ctataatgca tgtgttagtt tctaatggaa tcttaatagg
    73081 agaagggttt gtagaaggtc taatgcagag ttctgaatta gaattaaata cgaatgtagg
    73141 tctatttatt caagaaatca tgaaataaaa aagggggaaa atttaaaatg aatgaaaaaa
    73201 gagtaaaagg agtaacatta actatactga cagaaagccc agttccactt tcgtatgacc
    73261 aagggtatgg aaattataca ccaataaaaa aagaacaata tagagataaa gtacatgcaa
    73321 aaactagtat agctacaata acatatgatt taagaagaat actccatcaa gaatatggtt
    73381 ggaatttaag taatattgtt tttggaaaaa aaggaaatat atatccatct attaagaaaa
    73441 atgtaggatg tgtagatgaa aatggattag agactgatgt atttggttat ttaataccac
    73501 ttaaagagaa aggttctata agtaaggctt ctccgcttag aataatacct tttaggtcac
    73561 taaattcata tagaggttca acacagttga taacaaatag aggtttttta agtagcgaat
    73621 ttggtagaaa atattatgat gagagggaag aaaatgaagt acttagagat gaaaactttc
    73681 caacaacaca agcattagca atagaagaga ctttatcaga ttactacgtt tatacaataa
    73741 cattggagct tgatagaata ggagtagtag aagtagaaga agatggaaag ttacttttac
    73801 cagaagaaag aaaatttatg agtaaggagt taagagaaaa agcagtaaaa gatatattag
    73861 atgcaattac tgtgtttaca agaaacataa aacattcatc agtactatta aaaccacttg
    73921 cagtaatggg tggagctttt gataaagttg taccattttt ttgggatgat gtagattata
    73981 atgctgatag tggtgagata aatttagagg gagtcataga aactatagaa agttatagcc
    74041 ttaaagaaag taacacaata cttgctatca atgacagatt aaaaatttct aataaaaagg
    74101 aattaaataa gtttaattta agtaaatacc ctgtaaaaga gattaaaaat ctagcagata
    74161 gattggaaat tggagaagat aatatgtggt atttaaaaga gtaggaggtt ttttgaatta
    74221 tgaaagtatt acaatgtaaa cttaagcaac caactgctca ctatagagac ccaaaagtat
    74281 ttcaaaatga atatataagt actttaaatt taccatctaa gaccacaata atgggaatga
    74341 taacgtattt atgtgataga agattaaact ctgatataga tataggaata attggaacac
    74401 atcatcatag agaactagaa ttttcaagag gagagaacat tgatttttgg aatgaatata
    74461 caaatatgag aaaaggcaaa gataaagaaa agtttttgct tcaaggaaac tactatgatt
    74521 actataaaga acataaagct caaaatagca tattaaacta tgaagttctt aaagaagtag
    74581 aactgactat atttatttct tgcaaggatg atgaagaact tgaatttatt agaaaaaagc
    74641 ttgaaagtcc atgtaaatat gcaaatttag gaagaaaaga agattttgta ataccaagtg
    74701 aaaaagggtg ttttgtgaaa gaagttgagt taaaagaggt tatacctatg aatactcgtg
    74761 atgctataaa agaaaatata aaattaaaga atacatatgt aagagttgac ttaagagata
    74821 aagagaatgt cgagactata ataaatcaag gtgtattgat tgcattacct tataaatata
    74881 aagatttaga agcaaataga gatgatagag tttatgagtt ttgccattat atatatgttg
    74941 ataatgatgg tatatatcct aaaaatatta aggtaaatgt atgtattgat acaaaagaag
    75001 tttttacatg gctttaaatt attttgaaag ataggtgttt atcatgaaaa atatcatgca
    75061 aaaagaaata ttagctaagt catataattt aagaactaat caacaagagc aaacattagt
    75121 tgaacatatt aaggatttat ttgaagtatt agaatctata ttagaactaa atctatattc
    75181 agataaagat gtagagatac taaaaatatg ttgtgctttg cacgatttag gaaaaattaa
    75241 ttcaattatg caacaaaaaa tggagattaa taataaaata tcgtatagtt gctcagaaga
    75301 agagaggaaa aagttagagt ctgacaaaaa atctttaaaa aagatagcaa gacataatat
    75361 attttctgga gcatttttaa aagatatatt agaaaaaatg aacttgtcag aagaagataa
    75421 gttatatata tataaaagta taatgttaca tcatggaaac tatgaagatt atatgaggtt
    75481 aagtattagt aaagttcaag aagaaattta tgagtatatt gaaaaaggca ttttagaaaa
    75541 agaagagttt aatctgaaag atatagaaag ttatataaat agcattttaa atgtagactt
    75601 taaatttggt gaagatgtat tggattatga ttacatagat aaattaagtg aaagtatgtt
    75661 tatagacagt gattataaca atggtcaaat agatgattca gttttaaatt atagaaagtt
    75721 taagtatatt ttatataaag ggatgctgaa cttaatagac catagtgcat caagtagaca
    75781 gaaaggtata aaattttata acgattttac tgatgaagaa attgataata tgattttaaa
    75841 tgagatatat aagagtcagg gtaatttgga aaaaaataat atagagttca atactataca
    75901 aaaaaggttg agagaacttt ctggaagaaa tgttctgact gttgcattta caggttcagg
    75961 aaaaacagct gcagattata gaaagacttt taaaagaaaa ttctttttag tgccaaataa
    76021 aatatcagca gaaagttttt atagaaaaaa tatttttcaa aataaaaatg atttagatac
    76081 aagaagtagt aatgattaca ttggattact tcatggagat ataaacttat attcagagaa
    76141 tgaagataat ggagaacatg attttgtatt gacattaagg gatatagatt tgagtataaa
    76201 cttttgtaaa ccttgtgtaa ttgcaacagt tgaccagtta ttacttagta tgtttaaatt
    76261 tccgggatat gaaaaaatat tcgcagccgt aaaaaatgca tctataactg ttgatgaagt
    76321 acatttattg gaaccaaaga tgtttttgat tttgatatat tttatgcagt ttgcatgcaa
    76381 gtacttagat gttgattttc acttaatgac agctacactt ccaaaatcat ataaagagca
    76441 aatgataaac aagggaatta tttttcaaga agaaagtaat gaaaatgtta ctgataaagg
    76501 agaaatagtt tttattgaga gcaacaagga agaagagatt tgtgaaggta aagatgtaaa
    76561 ggtttctttt ataaaggaaa aagaaatcaa gtcaatagtt gaagatgctt tagaaaataa
    76621 acaaaaaatt cttataataa agaatactat tgattcagtc aatagaacat atgagttttt
    76681 aaaagaaaat ttatctgata agtatggtgg tgtagatata gatgttttac atagtagatt
    76741 taagttcaaa gataaaaaag agaaatatag taaaatatta aatggagagg gtgatatttg
    76801 gatatcaact caatcagtag aaatatcctt ggatttggat ttcaatataa taataagtga
    76861 tttagcaact atggatagct tgatacaaag aatgggtaga tgtaatagaa ataataaata
    76921 tgaatatgga aacttttata ttctacctag tgaagataaa atttatgata acaaacttaa
    76981 gaacacaact aaaaacatct taaaggacat attaaaaact aactctattt ttacaatggg
    77041 aattagaaaa actattttgg atgattacta tgataatagt gtagtcaaaa aatattttga
    77101 agagaatttt ataagttgtg ataaagaaat taagaatatt tatggtataa ataaagaaat
    77161 ttttgatgga ttggatttaa tttttaattt tgaaccttac aaaaatattg ttgatagtaa
    77221 gaaggaagca gctaaaattt ttagagatgt tgatgttagt tacaaaatta ttctggaaga
    77281 agatttttat aaggaagata gagagttaca acaagattcg attcaagtat cagggtttat
    77341 atttaataga ttatattatt atgggttaat aagcaaagta gaaggataca tggtactaaa
    77401 atctagtagt aagtttgagt ataatagtac tgtaggctta attttgaagt gagcatatgt
    77461 ttaaatataa tataccttta gacattgaaa atacaaaaag tactactgta agctcactgt
    77521 aaaaactatt tttttaaaag gaaaaataag ttgtgagata gagtgtttac aagtgtatat
    77581 agataataaa tttgaggttt aagattaact aagtgggttt caggtacatc gcgaaaataa
    77641 ttataagttg gagattttgt atgtttaaga ttaactaagt ggatttcaaa tattgatata
    77701 gtagatataa tagaagtttt attattaggt ttaaaattaa ctaatcggat ttttaaatat
    77761 tctgactatt atataaggat attattagct tgaatttaaa accaataata taaaacaaca
    77821 aaatattata tttatgatat aataaaagtt atggaaaaac aggaatatta ctatagagaa
    77881 gagaggtaaa cttatgaata attggataga agtaactata aaaacaacaa cagaagcagt
    77941 tgaacctata acgaatatac tatatgaaca aggagctgga ggagctgtaa tagaagaccc
    78001 aaaagacttt ttattccaaa agaaaaatga actagactgg gattatgttg aagaagaagt
    78061 atttaaaaag aatgaagaag atgatgttct tataaaaact tatgtttctg aagaaaaaaa
    78121 tgtgatggaa tttgtcgaaa taataaagcg aaaagtttta gggttaaaag attttggtat
    78181 agatataggt gaaggaagtg tatcattgga ccaagtaaat gaagctgatt gggcaaatgc
    78241 atggaaagca tactacaaac caacaaaagt aggacaaagg gtagtagtaa agcctacatg
    78301 ggaagattat gctatgcaag agggggattt aatcatagag cttgaccctg gaatggcatt
    78361 tggtacaggt acacatgaga ctactagtat gtgcattaga gaattagaaa agtacgtgaa
    78421 taaagattct aaagtatttg atattggctg tggtagtgga atccttgcaa tagcagcagc
    78481 taaattagga gcaaaagaag ttgtagctgt agatttagat gaagtggctg taaaagttgc
    78541 aaaagaaaat gttcttgaaa ataaagttga aaaaagtgta tctgtaatgc atggtaattt
    78601 aactgatgta ataaaagata aagcggatgt aatagttgca aatataatag ctgatataat
    78661 aaagatactt gcaaaagatg ttcaaaactt tatgaaagaa gatgctatat tcatatcttc
    78721 aggtataatt ttggataaag tagaagaagt taaagaaagc ttaattgaaa atggatttga
    78781 aatagttgaa gttcaaaaat taggtgaatg gtcagcaata gtttctaagc ttaaaaaata
    78841 agggatatgg tgacgtataa tggatagatt ttttgttgaa aaaaataata taaatctaca
    78901 agataaaact tgcactatag aaggtgaaga tgtaaaacat atttcaaaag ttttaagatg
    78961 caaattaggt gagaaacttg aaatatgtga caagaataat aatgagtata tttgtgagat
    79021 aatgaatata gataagagta tagttaattt agaaatttta gaaaaagttg atataaatag
    79081 agaatcagaa cttaaagtaa ggctatacca gggacttcca aaagctccaa aaatggaaat
    79141 gatacttcaa aaattaactg aagtgggtgt agaagaaata atattagttc aaactaagag
    79201 aagtgttgtt aaagttgatg acaaaaaaga agataaaaaa tttgaacgtt gggaaagaat
    79261 aatttatgaa gcagcaaagc aaagcaaaag aggtaagata ccaaaattaa gaggtgtttt
    79321 aagttttaaa gaagctttag aagatatgaa aaaaaataat gtaaatattt gcccttatga
    79381 aaatgaaaga acagtttcaa taaaacatgc actaaaaaaa tgtgattcta atatagatag
    79441 tgttggaatt tttataggtc cagaaggtgg attttctgaa gaagaaatag aacaaataca
    79501 aaaaaataat tgtaatgttg tatcattggg gcctagaata ttaagaactg agacagcttc
    79561 tgttgtagca tcaacaatag ctttgtatga actaagtgat ttaggaggag aaaaataaat
    79621 tgaaaaaagt agctttttat acacttgggt gtaaagttaa tcaatatgaa acagaagcta
    79681 tgctagaact atttgagaaa gatggttatg aacaagtcaa tagtgaagag tatgctgatg
    79741 tttatgttat aaatacatgt acagttactc atatgagtga tagaaaatct cgtcaatata
    79801 taagacgagt taaaaagaag aatccagatg caataatagc cgttgtagga tgttattctc
    79861 aggtatctcc agaagaaatt ttggatatag aagaagtaaa tttagtcatg ggcacaaatg
    79921 atagaagaaa gattgttgaa gaaattaaaa agataaattc aagtaagaaa gttagtacag
    79981 ttgatgacat aatgaaagtt aaagcttttg aagaaataga aatcagccaa actaatggaa
    80041 agactagagc atttatgaaa atacaagatg gatgtgacag attttgtact tattgtatca
    80101 ttccttatgc ccgaggacgc gttagaagta gagatattga tagtatagtc gatgaagtga
    80161 aaaaattggc taataatggc tataaagagg ttgtattaac aggaatacat gttgcctctt
    80221 atggaaaaga tttaaaggat agggatatta aacttcttga tgtaataaaa caaataaacc
    80281 agatagaaaa aatagaaaga attaggctta gttctgttga accaatttta tttacagatg
    80341 aatttgtaaa tgaagtttta aagatggata aagtttgtcc tcattaccat ttatcacttc
    80401 aaagtggatg tgatgaaact ctaaaaagaa tgaatagacg atacacaact ttagagtaca
    80461 aaactattgt agatagattg agaagtaaaa tgccagatgt ggcaataact acagatgtaa
    80521 tagtaggttt tcctggagag acaaatgaag agtttaaaaa aacgtacgag tttttaaaag
    80581 aaatagagct ttcacaaatg catattttta aatattcacc aagaaaagga actccagctg
    80641 caactatgga aaatcaagtt gaccctcaaa tgaaacactt tagaagtgaa caacttttaa
    80701 atttaagtaa agtaaatttt aataaatttg caactaaatt tatcggccgt gagttggatg
    80761 ttttatttga acaaaatata gaaggcaata aatatgaggg attaacttca aattatataa
    80821 gagttgttgt tgaaagtgac aaaaatatac aaggtcagat attaaaagtg aaaataaatg
    80881 atgtaaaaga tgaatatgta gaaggaattt tgctataaca tgtagaaatt ataatattta
    80941 taagatagga ggtggaaaga atggattgta ttttttgtaa aatagcgaac ggagaaatac
    81001 cttcaactaa agtttatgaa gatgatagag tcttagcttt taatgacttg aacccagttg
    81061 ctccatatca tatattagtt gtacctaaaa aacattatga tagtttaatt gatattcctg
    81121 ataaagagat ggacattgtg tcacatattc atgttgttat taataaaata gctaaagaga
    81181 aaggttttga ccaaactgga ttcagagtca taaataattg tggaagtgat ggagggcaag
    81241 aagttaaaca tttgcactat catattttag ctggtaaaaa gcttcctaat tacgaagcgg
    81301 gacaaaacta aactaaatta ttgaaaaatt gagttccttc ttgataaaaa tacttgataa
    81361 aagtaaaaat ttagtttata ataaacaaag tgttaggttg taatgcatat tatgcaaaaa
    81421 gaacatagtt acagtcccag cataattgcg ctattggagg gagggaaaaa gaaatgtcag
    81481 aagtaagagt tagagagaat gaaacattag acagcgcttt aagaagattc aagcgtcaat
    81541 gtgcaatgtc tggcatcatg tcagaagtga gaaaaagaga gcactatgat aagccaagcg
    81601 ttaagcgtaa gaaaaaagct gaagcagcaa gaagaaaaaa cgctaagaaa tagtagtaaa
    81661 taagaataaa gaggtgaagg ggatgtccct taagcaaaag ttacaagagg atttgaaatc
    81721 ttcgatgaaa aacaaagata cagtgagaaa atctgtagta actttaataa gagcttctat
    81781 aaagcagtat gaggttgata atagggtcga gcttgatgaa gatggaatta tcgatgtaat
    81841 agcaaaacaa ttaaagcaac gtagagatgc attagttgaa tttgaaaaag ctggaagaga
    81901 agacttaata aaagaaacag aaggtgaaat tgaagtttta aaagagtacc tacctcaaca
    81961 attaagcgaa gaagagttag aagaaattgt aaaatctact atatctgaag taggggcaac
    82021 ttctatgaag gatatgggaa aaataatgtc agttatccaa ccaaaagtta aaggaagagc
    82081 tgacggaaaa cttataaata agttggtaaa acaaaactta caatagattg atatagccta
    82141 gagagaaatc tctaggcttt ttatagtttt tgggaataac gagtcatatt tgagcatatc
    82201 tataatcaaa gaaaattttg aaagaagggg aaaaatttga ttatatcagt aaaagagatt
    82261 aggaattttt tgataaacat atttatacca ctaataatag gttacttaag tagcatctta
    82321 acaatgatta tcagtggaac agatatttca acctattatt tacaactcac aaagccaagc
    82381 tttgcaccac cagcttttat ctttcctata gtttggacta tattgtacat attgatgggt
    82441 atatcttcat acctaatatt aagaaagggt tacaacttac ctaaagtaag agatgcaatt
    82501 ttttattatg gattacaact tgtattaaac tttatttgga gtatactatt ttttggattt
    82561 ggacttagat ttacagcttt gatagatata ataataatga ttttggtttc tataataatg
    82621 atttcgaagt tttctaaaat agataagaga tctggataca taaatttgat ttatttaatg
    82681 tggcttgttt atgcaggatt tttgaactat tttatatggt ttattaataa atagaatgta
    82741 aagattttgt aaattaccct gtacttttaa taatatcata acaaacgaaa aataaataga
    82801 ctattaaaaa taatcatttt catatacaat aatattaatt taaatacaat aaatttataa
    82861 aaattgtatt taaagattaa catattaaag tattagaatt ggaaaggctt gaagggagag
    82921 gtttttatgc aaataatagt atctgggaga caaatgaaat taactgacgg aataaaagga
    82981 tacgtagatg gaaaattaag taggttagaa aaataccttg atcctgaatc agaagtgaaa
    83041 gtaacagtaa gtgcgaaaaa ggatagacaa aaagtggagg ttacaataat tcctattaac
    83101 ggtcaaataa taagagcaga agacgtagaa gatgacttat atgcagcaat tgatattgtt
    83161 tgtgacaaat taagtagaca agttgtcaaa tataaaacta aagttaaaga caaagttcaa
    83221 aataataaga gcataagatt tgaaaatctt gactttatag ataatagcag tgaatttgat
    83281 gattatgatt atgatgatga agaagatgag aatatagtaa tagaaagaag aaagaaattt
    83341 aatgtaaaac ctatgagttc tgaggaggcg atacttcaaa tggaactagt aggacacaat
    83401 ttctatatgt ttagaaacca agataatttt gaaataaaca tagtgtataa gcgtaaagct
    83461 ggtggatatg gtttaataga acaagattaa taaaaattgt atacgtttag attttatata
    83521 agaaaaaata aaaaggtaat catgttgatt ttttatcaat atgattacct ttttcttgtt
    83581 taaataatat attagatatt aggtatttat tatataaaaa ttttaaaact aatctgttac
    83641 aacatcaata aagtgcataa atacctattt caagcataaa attaattaag ggggtaatgc
    83701 ttatgttaga aatatccact gatttacaag taaatcaacc agttattact gttacaagta
    83761 atacgtttat tagtatagaa aattatctat caatattaga atatgaagtt gatttaataa
    83821 gaataaagac taaagttaaa acaattaaaa tatctgggga taaactttca cttaagtata
    83881 ttactgatag tgagataggt ataaaaggga ttatctacaa tgttgagtat gttgattagg
    83941 aggagataca cttgataagt tttataaggg gatactatgt tatagttgtg gaaggagtag
    84001 gactcgaaca atttttaaat catcttataa gaaatgggat aagtgtttac aatgtaacta
    84061 gaataaaaaa tactaaaatg gagtttcata tagatagaca agatataaaa gaatttaaga
    84121 atgtttatag aggaagtaag tttgatataa aggtaaagca aaaaactggg gtccctttta
    84181 ttatcaaaag agtttataag cacaaaggta tgtggatttg tgctcttgtt tctttatttt
    84241 tattgatgtc tacatcacag tttgtgacag atgtatatat acaatctcct gaaggtataa
    84301 aaaaagaagc tcttagaaat gagctttata aggttggagt aagaccagga gtctataaga
    84361 agagtattga tagaaaagaa gttagagacc atatgatgtc aaaatttaat gatgtggcat
    84421 atttatctat caatgtaaaa ggaacaaata tatttgttac tgttacaaaa aaggcagaat
    84481 ccctaaaatc tacagaccaa tcaaattatt gtaatgtaat tgctttaaaa aatggtataa
    84541 tagaaaaggt aatccctaga agtggtaaat cagttattaa atctggagac atagtccaaa
    84601 agggagatgt cttattaaat ggagctaata ccaagtcaat accagaagta tgggcaagta
    84661 ctttttatga gtccacaaaa aaggcaagtt atgtagatac tgtaaataaa aaaactggag
    84721 aaaagaaaaa tatatataca ctaagttttt atgataaaga gtttacaatg agaaaaaata
    84781 taaaatataa agattatgtt gttgaaaata aagaaaaaaa actatcaata ggaaactata
    84841 cttttccaat aaagataaaa acgagtactt tttatgaaac aaaaaaggtt gaagtaaaaa
    84901 ggaataaaga agagttaaaa aaagaattat ctgaaaaagc tttaaaagag ttagaataca
    84961 taatcccagc ttcggctaga ataatagatg taaaacataa ctttaaggtt aataaaaata
    85021 tgttagaata tttaataaca gttcaaacta gtgaaaatat tgctaaaatt tatcctctta
    85081 gtaagtcaga agcagaaagg tttataaagg aagaaagtaa accagatgaa ggtgaagagg
    85141 aagttccttc caatccagaa aaaagaccat taaatgatat aagaaatgag tttgatgagg
    85201 ataataagga taataaagat caaaacaatt ctgatgaaaa taatagtaat caaaatagta
    85261 ataatagtca aaataataat agcaataaca actaataaaa ttaaacttaa aatcttagga
    85321 ggactaattc aattgataat acaaaagaaa tttacaatag cagatggtaa ctttgaaaga
    85381 gagttatttg gcaactttga tgaaaatgta aaattaatag agaagacttt aaatatagat
    85441 gtaatactta gagaaggcaa tataatttta attggagaag aaaaaaatgt agattctgca
    85501 ttaaaactta tgaatgaatt acaccaaact gtatcaaatg gtaagcattt agataagcag
    85561 agtatttctt attcattatc tcttttgctt gaaggaagtg aacaaaaaat aaaagaactt
    85621 gaggggacaa tcgtcataac tcaaagggga aaagctgttc aacctaaaac tttaggtcaa
    85681 aaagaatata taaaacttat agaaaataat gatataactt ttggtgttgg acctgctgga
    85741 acaggaaaga cttatcttgc ggttgctatg gcagtaaaag cttttaaaag agatgaagtt
    85801 agtagaatta tacttacaag accagctgtg gaagcaggag agagtctagg ttttttacca
    85861 ggagatttaa aggacaaagt tgacccatat ttaagaccac tatatgatgc cttatttgaa
    85921 atgttgggtg ctgataaatt taataagtat ttagaaagag gtactattga ggttgcacca
    85981 cttgcattta tgagaggtag aacacttgat aattcattta taatattgga tgaagctcaa
    86041 aatactactt ctgaacaaat gaaaatgttt ttaactagac ttggatttgg ctctaaagct
    86101 gtagttacag gagatgtaac tcaaacagat ttaccacaaa ataagaagag tggtctaata
    86161 caagctacag agattcttaa aggtgttcca ggtattgggt ctataatgct aacagataga
    86221 gatgttgtaa gacatgagtt ggtacaaaga ataataagag cttatgagaa gcacgacaaa
    86281 agagaagaat ttaaaaaaga agaacgtaaa aaagcgaaaa tgcaggaaaa gactttcaaa
    86341 agaaagtaaa agtgtagtaa tatagatata tagcattatt aatgaataaa aagtaggtgt
    86401 agtgaatgga tttgatacta gatgatagac aagataaatt agaagtaagt gaggagttaa
    86461 ttgaaaagat aaaggatata atcatagaat gtttagatta tgaaggatat gatgataatt
    86521 atgaagtgag tctttctttt gtagataata aagagattca tgaattaaat agagaatata
    86581 gaggagttga tagagtgact gatgttttat catttcctct tttaagtgat gattttgagg
    86641 atgttgagtt agaagaagaa tccctaggtg acatagtagt atctcttgaa agagccttag
    86701 aacagagtat agagtataac catagctttg aaagagaagt atgtttttta atatgtcata
    86761 gtatgtttca tcttttaggt tatgaccacg atacagatga aaatacaaaa gaaatgagag
    86821 aaaaagaaga acacatatta aataagttaa acataacaag ggagtagttt ttatgaaacc
    86881 agaaaaaact cgtcaaggta taattaaagc atttaatgca gctatagaag ggatattgta
    86941 tacatttaaa tttgaaagaa atatgaaaat acattattta ggttcagttg ctgttcttat
    87001 aataagtttg ttttttaact tttcaaaatt agaaatgata atgttactta tgtccatatg
    87061 cttagttgta gttgctgaaa tgtttaatac agctatagaa aaagctgttg atttagtaac
    87121 tgatgaatat catgttcttg ctaagatagc aaaagatgtt gcagctggag gcgttctagt
    87181 ggcagcacta aattcagtag tagttggata tattttgttt tatgataaat tgacagatat
    87241 atctggaata ttaatttata aaataagaga atcagaatta catataacct tgatatgtat
    87301 attattggtt cttatagctg ttgtagttgt aaaagcattg acttctacag gtactcctct
    87361 aaaaggagga atgccaagtg gtcatgctgc cttagcattt gctatagcaa ctgcaattac
    87421 acttatgact gaaagagttg ttgcctctac tcttgcatat ataatggctg tattagttgc
    87481 ccaaagtaga attgaaggaa aaatacatac cttttgggag actattgctg gagctttgtt
    87541 aggtgtgttg atagctatat tagtatttca gcttggaatg ttctataatt aaaataaatg
    87601 tacataaaat atttaaaata aaacaaatct gtgctaatta aatttttatg atataatgta
    87661 gagtattaaa taaaaataac ttttaattat tgtatacagg aggagttgtt gtggataaca
    87721 tagaattgtt aaggttggca gaagatgcca gacaacattc ttatgctcct tactcaggtt
    87781 ttagagtagg tgcagctctt ttaactaaga gtggtaaagt ttatactgga tgtaatatag
    87841 aatgtgcatc attaggtgga acaaattgtg cagaaagaac agctattttt aaagcaatat
    87901 cagagggtga taaggatatc tataaaatag ctatagcaag tgataactca gaaaataatg
    87961 agcaaacata tccatgtgga atatgcaggc aggtaattat agagtttggt tctgatataa
    88021 aaataataac gggatatact aaaggagagg tgtttgagca tagtataaag gatttgttgc
    88081 caaactattt ctctggaaat gatttaaaat aaatttaaaa gtataaataa atttaagtaa
    88141 ttaaaacaag aagataaaaa gttaggagac agttaatgtt caaatcaggt tttgtcagta
    88201 tagtgggtag accaaatgta ggaaaatcta ctttaatgaa taatgtagtt ggagaaaaaa
    88261 tagctataat gagtgataag cctcaaacta caagaaatac aatacaagca gtatatacag
    88321 atgaagaaat gcagatagta ttcttagata caccaggtat tcacaaacca aaaaataaat
    88381 taggtgaatt tatggtaaag gcagcaacag aagcttttaa aaatgtagat ttaatattat
    88441 ttgtagttga tgattctaaa aaaataggtc ctggagatag aaagataata gaggatttaa
    88501 gaagtgttaa gacaccaata attttagttg taaacaaaat agaccaacta gaccaaaaag
    88561 atgagctatt tgatataatc aaaatgtatg atagagaagg catttttaaa gaaatagtac
    88621 caatatcagc attaaaagga aagaatacgg ataccttaat aaaagttata caaaattatt
    88681 tagaagaagg gccaaagtat tttccagatt atatgattac agaccagcca gaaagagtat
    88741 taatagcaga acttataaga gaaaaagttc ttcactatct taatgatgaa atacctcatg
    88801 gtgtagctgt tgaaattgaa aaaatgaaag cgagaaatga taaggaaata gtagatgtat
    88861 ctgctgtaat atactgtgaa agagattcac ataagggaat aataatagga aaaaatggta
    88921 ggaaactaaa aggaataggt aagtcagcaa gacaagatat agaattgctt ttaggttcac
    88981 aaataaatct tcaattatgg gttaaagtca aagaaaattg gagaaattta caaaattata
    89041 taaataattt tggatataat gataaataaa ggtgggttat atggatagga aactggatgc
    89101 ttcccaagat ttattatatg aagtaaaatc attaattgat aataataaag tattggagtt
    89161 aagagaatta atagaggaat atcatataat tgatatattc gatataatgg aaaatttaga
    89221 ggaagacatg aaaattcaat tatttgaagt acttccttta gatatggcat cttctatatt
    89281 agaagaaggt agtgtagagt tttttattag tattttatct aaactggatg tagaacactc
    89341 gaaaaatata cttgaactta tgtctcttgg agatatggca gacaagttga gtgaacttga
    89401 agaagaagaa agagaacaca taataaatct tttgaatcaa gagaatgccg attatgtaaa
    89461 agagttacta ttctatgatg aagattctgc tggtggaaca atgaccactg gatatatttc
    89521 tataaataaa gatatgacag ctcttgaggc tatagaccat atgagagaag aagctgaaga
    89581 agctgaaact atttattata tatatgtggt tgatgatgaa gaaaaactag ttggagtatt
    89641 gtcattaaga gaattaataa tagctagaga cgcaaatata gtagaagatt tgatgagtga
    89701 aaatataatc tctgtttatg tagatgaaga tagagaagaa gcagtaagat tagtatctaa
    89761 atacaattta atagcaattc cagtagtaga cagacaagaa aaattaaaag gaataataac
    89821 agtagatgat ataattgatg taatggaaga agaagcaact gaagatatgt ataaatttgc
    89881 aggaagttca gaacatgaaa gagaagttgc tgaaaaagaa aaccctacat tgagagagca
    89941 aataatatca gcacttagag gacgattacc ttggttaatt attaccttag ttggagggtt
    90001 gttggcttcg ttaatacttt ctaacttaga ctatataatg aatcctgtat atgctccatt
    90061 agtatttttt atacctgtag taattggtat gggtggaaat attggaactc aatcatcatc
    90121 tgttacagta ataacattat ctaataagga tttaaatttt agcaatgtgg ttagagaagg
    90181 tattgtaggt attattacag gtcttttgtg tagtataata acaggtattg taatttactt
    90241 tgttatgaga aagttagaca ttgtattaat tgtttcaata tcattattta taaatatggt
    90301 tttaggtgca acaataggtg cgtttatgcc tgttttatta aaaaaaatgg atgcagaccc
    90361 atctacagtt tcatcaccaa ttatatctac agctcttgat ataactggta tagcagttta
    90421 ctttataata acaacggcat tattgtcaaa aattgtttaa taactttatg tatgatttat
    90481 cctcttctta ctaaaaatat aagtataaat gtaagaaggg ggttttttaa aaatgaacaa
    90541 tatcagttgg gaagttttta aaaaaacagg tagtatagat gcatatttat atttctgtga
    90601 ttgcaaaaac atacatgaag aaattgaaga agtaagggag aaaaaagaag acgatgataa
    90661 tcctgaacac ccaggggata gtacttaaag ctataaggta taaggaaagt gatataatac
    90721 ttacactatt tacaagaaag cttggaaaag tatctgcaat agcaaaagga gctaaaaaaa
    90781 ataagagctc tttgctttca tcatcacagt tattttctta tagcaatttt accttaaaaa
    90841 aacaaggtaa tatgtacaag gttactcaaa gtgaaataat aaaaagtttt tataatatat
    90901 cctatgatat agaggcattt tcttatgcta catatattac aaaattagtt gaaaattcta
    90961 tacttgaaaa tcagactaat aataggctat ttatattact tgcgcagact ctgtatttgt
    91021 atacacagga taatacagac aataggttta taacagcagc attcgagtta aaatttttag
    91081 actatatagg atttaaacct atagtaaata aatgcattaa ttgtgaatgt aaaattttac
    91141 aaaattctgt gtttaatatc tacgaaggtg gtatactatg tagtaagtgt agtaaacttt
    91201 ttgataataa tataaaatta gacttaacaa ctataagtct tatggaatat gtattaagaa
    91261 atgatatttt aacatgtagt aaagctaaag tatcaaaata tataacacat gaacttgaga
    91321 atattctaga caagtatttg aaagtttatg ttgataatat taattttaaa tcattacacg
    91381 tattgcaaag tgtaaaaaat aataagggag tggataatga tgagtagtaa tataactatt
    91441 gaaatggttg attcagtctt tgaaagagtt ccaggagcaa cttatgcaga agcaaaagaa
    91501 gcattagtaa tgtgcaatgg agatgtaatt gaggcagtaa tatatttaga aaataaaaaa
    91561 aatacttgta attgtaaagc aaaatctgct aaagaaacta tggaagaagt atttggcaaa
    91621 gatggagaaa atataaagtt tcaattaaaa gagcttctta gaaaaagtag tgtagtgaga
    91681 ataatagttg aaaaagatgg aaaaactatg atgaatattc ctttaacagt tggagttgtt
    91741 ggattagctt ttgtaccatt agctacttta gttggattat cagctgctgt tataagtaaa
    91801 tatcgtataa aagttcaaaa tgaagaagat ggagaaattg tagatttagg tgaattgaat
    91861 gaagaaaaac ttcacgtttt gaagaatatg ataactaatg cagcaaaaga tgtgaaggat
    91921 gtagtagttg acaaaaaaga agatgacaaa gatgtaactg ctgaccttat gaaagaagaa
    91981 tctgaaaaga ataaagaaga cgaagacgaa aataaataga tataaagtga cttttaaaaa
    92041 atgaagagaa gataattata agaattatca ctaacattga caaattttat agaatttgat
    92101 attctaaaag ttgtagaaga actattaaaa tagcctttcg tgtagacgag aggctttatt
    92161 gttataggag ggatttttat gaattttcaa gagatgatac tggcgttgca aaaatactgg
    92221 tcaaagcaag gttgtatcat gatgcaacct tatgatattg aaaaaggtgc gggaactatg
    92281 aatcctaata cttttttaag atcattagga cctgagcctt ggcaagtatg ctatgtagag
    92341 ccttcaagaa gaccagcaga tggaagatat ggtgaaaacc caaacagact atatcaacat
    92401 catcaattcc aagttatact aaaaccttct ccagataata tacaagaatt atatttggaa
    92461 agtttgaaag agattggaat tgacccaagt gagcatgaca taagatttgt tgaagataac
    92521 tgggaagctg ctacagttgg tgcttgggga cttggatggg aagtttggct agatggtatg
    92581 gaaataactc aatttacgta ttttcaacaa gtaggtaata ttgaatgtga gcttgagaca
    92641 ggagaaatta catatggatt agaaagatta gctatgtaca ttcaagaagt tgatagtgtt
    92701 tatgatttaa aatggaatga taaaataact tatggtgaag tatttaataa agctgagtat
    92761 gaaaactcaa tgtacgcatt tgaattatgt gatgcagata tgttgtttaa tctgtttgat
    92821 atatatgaaa aagaagcatt aagacttatg gaaaatggcc ttgtaatacc gtcatatgac
    92881 tatgtgttaa aatgctctca tgcatttaat acattggatg caagaggtgc aataggagtt
    92941 agtcaaagag cttcatttat aggtagagtt agaaatatgg caaagactgt tgcagaaact
    93001 tttgtaaaac aaagagaaga aatgggattc cctcttttaa aggacggtga caaataatga
    93061 aaaattatct tttatttgaa atcggtgttg aagaaatgcc atcaagattt gtaggcagta
    93121 cactagaaca attaaaaaac aatcttagta aattatttga tgaaaataga atagcttttg
    93181 ataaaataaa tgcttatggg acaccaagaa gacttacttt agtagtcgaa ggattgagtg
    93241 atagacaaag tgatttagaa gaggaaataa agggtcctgc taaaaaaatt gctgttgatg
    93301 cagaaaataa tttaacaaaa ccagcattag gatttataaa aagcaaagga ttaagcgaat
    93361 ctgacatata ttttaaacaa gttggaaaag aagaatatat atttgcgact ataaagcaag
    93421 atggaaaaga aacttcagaa gtactaaaag acatattacc agagactata aaatctgtag
    93481 tattcccaaa agctatgcgt tggggaggaa aaaatcttaa atttgcaaga cctataagat
    93541 ggatagttgc attgttaaat gataaagtat tagagtttga tttagaagga ataatatctt
    93601 ctaatgtaac aaaaggtcat agatttttag gtgaaagtac aatagaagtt gattctatag
    93661 aagattattt tgaaaaatta gaaaaaaatt atatagtttt agaccaaaac aagagaaaag
    93721 aaatgataag aaaacaatgt atagaagtag caaattcttt aggtggagaa gttgaatttg
    93781 atgaagattt acttgaagag gtaacttatt tagttgaata tccaactgct ttttatggag
    93841 aatttgatgt ggattatata aaactaccaa aagaagttgt tataactcct atgaaacaac
    93901 atcaaagata ttttccagta cttaaagaag gaaaactgtt acctaacttt atagctgtta
    93961 gaaatggtga ttcttacaga atagacaatg ttaaagctgg aaatgaaaaa gttttagaag
    94021 caagacttgc agatgcttta tttttctata gagaagatac taagagaaac ttagaaagct
    94081 acatagaaaa attaaaaact gttgtattcc aagtaaaatt aggaactatt tacgacaaaa
    94141 ctttaagact tgaaaaatta agtgctgata tacttgatag tttaggttta gtagatgaaa
    94201 aggcagatac tataagggct gctaaattat ctaaggcaga tttagttact ggaatggtag
    94261 gagaatttga tgaattacaa ggttttatgg gaaaagaata cgcaaaagtt ggaggagaaa
    94321 atgatgttgt aagtgaagct atttttgaac attatcttcc aagatttgca ggagatatac
    94381 ttcctaagac taatgcaggg gttgccttat caatagctga taagttggat tcaatagcag
    94441 gtttctttgc tataggaata caaccaacag gttctcaaga cccatatgct ttaagaagac
    94501 aagctttagg tatacttagt atacttatgg acagaaaagt tgctgtggat ataaaaatac
    94561 ttattgaaca tgctttagac aattattctg aattagattt taataaagaa gaagttgttg
    94621 agcaaataat gaatttcttc aatgagagag taaaaaatct atttaaagat ttaggaataa
    94681 gatatgatgt tgttgatgct gttttaagtt ctgatataaa tgatgtttct gatatgcata
    94741 tgagagcttt agagcttaat aattggctag aaaaagatga attagtggag atgcttactg
    94801 catttaatag agtttctact ctagctcaaa aagcagaaag tgataaaatt gatgaatctt
    94861 tattaaaaga agatgctgaa attaaacttt acaatgaatt taaacaagta aaggtaaaag
    94921 ttaatgaatt attaaaggat aagaaatatg gtattgcttt agatgaattt gcatctttaa
    94981 gaccagtagt tgataattta tttgatacag ttatggtcat ggataatgat gaagctatta
    95041 agaacaatag acttgcttta cttaaacaag tatatgatac tatgctagga atttgtgatt
    95101 tatctaaaat tgtttataaa taaaatttaa actatttata agaaataagg ctgtctcaaa
    95161 atagagatag tcttattttt cattgttgag atgatgaaaa tatatttgat ttcatagaaa
    95221 aagagtgtct cataaactaa aaagttcatt ttgagacacc catgtttttt gtaagtaaat
    95281 ataataaatt atattttata cttatcagtt attttgttta aaatattatc atttgaattt
    95341 acccattcat aaaaattgcc tgaagatgcg tccgatattt tataaagcat ttcaggaata
    95401 tcactagctt taaaatctcc aagtgatttt cccaatctag tcttacctat ttcaaaactg
    95461 cctccaacaa ataattcaaa tgcatctgta gatataccat caacattctt ctttttacca
    95521 cataaaccta tgctaccaac ttgatgaaca ccacatgaat ttaaacatcc tgatatatat
    95581 aacttaggtg ctttatttaa aatttcttca ttattttgta atctaaaata atctatgatt
    95641 tcatgtaaca ttttctgact attttgtatg cccatttgac aaattggaac acctatgcaa
    95701 gatatacttt gttctaattg agaattacaa ctaatagttt tacttatttc taatattctt
    95761 tttgcttcat ttccatttaa atttaaaata tataatccct ctgtcattcc tagtctaatc
    95821 ataggatttt caacattatc taattcttta agtaaagtac ttaaatcctt tgttaacaaa
    95881 atacctccaa ctggatgtat atatacagtg tataaaccat cctgtttttg aggtattagt
    95941 ctagaatctt gtatatctat tttaactcca ggtttagagt aatctatttc ttcaatattg
    96001 agttcaagac taccattttc tttttctaat ttatagtatt ctttaaattt ttctaagaat
    96061 agttcttcac caagtgattc gaccatatat ctaaccctag ctctgttttt attttcataa
    96121 tttccataat ccataaagaa tttaatcata ccttcaacac aatataaggc gtctttcggc
    96181 tttataagtt catcaagttc taaagcaact ttgggttgtt tacctagacc tccacctaag
    96241 aaaactctga aatatggttc atcatttttc aaagtagcaa caaatcctaa gtcttgtata
    96301 ctacaatgag cagtatctgt gtaacaatta gaataagaaa cttttaattt tctaggtaaa
    96361 tggtatgtag tagcattttt gataaaatat ttatcagtag caactgcata tggagtaaca
    96421 tcaaagactt cactagggtc aactccagat aatggagata atccgacatt tctaggataa
    96481 ttaccaccac cacctctagt gaatatatca ttttttattc cttcttccat gatatcaaca
    96541 attgaattta tagataaatc gtgtaattgt atagcttgtc tagttgttaa gtgtatctta
    96601 tctaagttgt gtttaatagc tatttcatag attttattaa gttgatactg agataaaact
    96661 ccagcagata ctctaagtct tatcataaaa gattttttgt ctctttgagc ataaacacca
    96721 tatccaccag aaaatccctt atattgcatt ttatttattt ctccatttaa aaattttgaa
    96781 gaatattctt taaaattagg tagttcattt aacaatatct ttttaaaatt atccattatt
    96841 tcacctcatt gttagtcttg tataaaaata tatctattgt ataatagata tatatattat
    96901 tatctagtca ggataaaaat ataacagaat aattctatta aaagtaagaa taataaggac
    96961 atagtgagta ttttgttttt attttacaaa ttaagtataa tatttttgtt ttataaaata
    97021 taattaagat aaatagataa ttttgtaatt ttaatatata atatttagta gagtgtggga
    97081 gtagcactta atatttgcag gaggagtttt tgtatatggg agaaataata aatgcattag
    97141 atagagccct agacataatt ttgctgttat atcatgaaaa gagagaaatg ggaataactg
    97201 aaataagtaa ggctatggga gtatataaaa gtactgtaca tagaactttg gttactcttg
    97261 aaaacaaagg ttttgttata caaaatgcag agaatggtaa gtattggcta ggaataaatt
    97321 tatatgcaat aggtatggtt gtgggagaaa aaatgtcatt gactgaaata gtaaaaccat
    97381 atacgaaaaa attaaatcaa gaatttaacg aagtagttaa tgtatctata ttagaagaaa
    97441 gagctcaaga ttctccaaga agtatcataa tacataaaga gtatggttca aatcaattac
    97501 tttcagtaaa tccatccgtt ggttcaagta gtgaatgtta ttgttcagca gttggtaaat
    97561 gtcttatggc atttaatgat tctatagatt ttgaaaaata tagaaaaaca ccaatacaca
    97621 agtatacaga acatacaatt gataattggg atgatatgat gcttttttta gcaaaaataa
    97681 aagaacaagg atatgctata gatgatgaag aactagaaca tggactaact tgtattggag
    97741 cacctatctt agataaaaat aataaagcta ttgcagccat aagtttgtca ggtccaacta
    97801 taagaatgag agaaggggac tttgagtata agattaaaag agttatagaa actgcaaaaa
    97861 gtatatctga actttttaga tgatttttaa tctcgataat aaaaataggc tatatttaaa
    97921 ttgttatttg taaatatcag tttaaatgta gcctattttt ctttaatcta aaattaaata
    97981 ttcttaaaat ttaaaatgtt attgaaatat ataagcgaat gtgttatctt ttaattaagc
    98041 aataaaaata gaacaaggtt ctatactata gaacaaaatt gatgcatata tagtatttat
    98101 acaaaatata aatattatat atttaaaatt aagtaaaaat attacataaa ggggagattt
    98161 gagaaatgga aaaagtcaag ttgagtgttg aaagatgtaa gggatgctat ctttgtattg
    98221 aagcttgcaa aaaagatgca ataagtcttt ctgactacac aaataaaaaa ggctttgtaa
    98281 ctattaaagt cgatgaagaa aaatgtattc aatgtggcgc ttgttataca atgtgccctg
    98341 atttagtatt tgagatatta taaattattt ttattagagg ggagaaaagg tatgcaaagt
    98401 ttattaatta aaggaaatga agctttagca gaaggtgcta tacgtggtgg ttgcagattt
    98461 tatgcaggtt atccaataac gccacaatca gaaatattag aaatgatggc atggagacaa
    98521 aaagaagttg gaggagtatt tatccaaggt gaatcagaaa tagccagtgt aaatatggtt
    98581 atgggagcaa gtgcacttgg agcaagagct atgacttctt catctggtcc aggattttca
    98641 ttaaaacaag aaggtattgc atattgggta tcagctggtt tgccagcagt tgtagcatgt
    98701 gtgcaaagat atggtatagg tgatggattt ataggagctg gtcaagataa ttattggcaa
    98761 gcagtaaaag gcggtggaaa tggagattat catttaatcg tgttagcacc taatagtgtt
    98821 caagaaaata tggatatggc atatgaatct tttgaattgg ctgaaaaata tatgcatcca
    98881 gtacttatac tttctgatgc tacaataggt caaatggtag aaccttgtat agcaccacca
    98941 atgaaagaat acgatatgga taaagctcca tgggctgcaa aaggaacacc tgtaggagaa
    99001 aaaaataaag taataactga tataacatat tttgaagacc aagatacatg gcaaaaaggg
    99061 tatatagaaa aaatgagaaa agttcaagaa gatgaacaaa gatgggaaga gatagaaata
    99121 gaagatgctg aagtggtatt tgtggcatac ggtatttcat caagaatagc agaaggtgca
    99181 gttagagatg ctagagcaaa aggaatgaaa ttaggtctaa taagaccaaa aacattgtgg
    99241 ccttacccaa gaaaagcatt taagaaatta agtgattcat tgaagggact tgtaacagtt
    99301 gaaatgaaca tgatggcaca gatgaaggaa gatgtaatta tagcatgtga taatagattt
    99361 ccagtatatt cagtagcaac agctcaatat atggcagaag taaatcaatt aatagatttt
    99421 gctcaacaga ttatagatgg aaaagctaag caagaggagg tattttaatt atggctaaaa
    99481 aagcaccagc aataatgatg tgtgaaaata tgttctgtgg aggctgtgga cactctatag
    99541 tcgatagaat tattggagaa gtattaacag aaatggatat atgtcaagat acaattatat
    99601 gttcagatat aggttgtaat catatgtttc aatttagtat gaatgtagat gttgtcgttc
    99661 cacctcatgg taaaatggga gcagcaatgg cagctatgaa aagagttaga ccagataaat
    99721 atatatttac aatagctgga gatggtggag cttatgcaat agggcttgga gaaactatgt
    99781 cagctgctac tagaaatgat aatgtaatat ttcttgttat gaacaataat atgtttgcaa
    99841 tgacaggagg gcaaatggct ccaactacta tagaaggtca atatacagct tctactccag
    99901 cgggtagaaa ttacgcagat catggttcaa catttgatgt tgtaaaagtt atgggaaatt
    99961 tagatatagc atatctagca agaggaacaa taactaaccc taaagaaata aatacaacaa
   100021 aaagatacat caaaaaagct ctagaaaaac aaaaagaaaa gaaaggtttt tgcttaatag
   100081 aagtgcttgt accatgtcca acaaactggg gattaaagcc agtagatgct atgaagagaa
   100141 ttgaaaatga acttgttcca aagtatccac ttggagaatt tattgattag ggaggaaata
   100201 atatgttgaa tgaaattata tgtgctggtt ttggaggaca gggagttctt acagcaggaa
   100261 aaattataat gtatgttgca tataaggcag aaaagaaaat tacatggttc ccatcttatg
   100321 gaaatgagat gaggggagga agtgcaaatt gcaatgttgt tgtaagtgat gaaaaaattg
   100381 caaatccttg tgtaaaaaat ccagatatac tattgggaat gaacagcgta tcagtagata
   100441 agtatgaaag tttaatgaaa aaaaatggtt atatgtttgt caatgaatca ctagtaagta
   100501 aggatagaaa gtacagagaa gacattaatg ttataaaagt acctgttact gaaatagcac
   100561 aaaatttagg caatgaaaaa gctgctaaca tttgcatgtt aggtgctatg gtaaagagtt
   100621 tggatttatt tacaaaagaa gaatttgaaa gtggtatgtg tgaatacttt gaaaatcaag
   100681 gcaaaggtaa attcaattct aaaaatgtag aagcatttga agctggatac gactacgaat
   100741 gaatatttta aatatttaaa ataattattg aaatacttat ttttatatgt tagtatttaa
   100801 ttaataaaat atagaacgtc gttctgaaca ataggacgaa gtctttaggt cggaatacaa
   100861 gaacgacgtt ctgtatagta gaactagggg gtgttaaatt gaaagtttta gtaataaatc
   100921 ctggtggtac atccacaaaa atttctgttt tccaagatga aaatgaaatt ttgaaaaaaa
   100981 atataaccca tacaagagaa gatttaaaaa atttttctaa agtatttgat gaatatgatt
   101041 atagaaaaca actgatagta gatattttaa gtagtgagaa tcatagtata aattcttttg
   101101 acgcagtagt tggtcgtggt ggacttatga aggctataaa aggtggtacc tatactgtga
   101161 gtgaagaaat gattgaggat atgagaaatg aaataaatgg ggaacatgca tcaaatttag
   101221 gtgcattatt agctaaaact atagctgatg aaataggagt acaatcattt gtagtagacc
   101281 cagtttctgt agatgaattt gatgatgtat cgaggattac aggaatatca gacatagaaa
   101341 aagcaagttg gttacatgca ttaaaccata aagctgtttc aagaaaaatt gcacaaaaac
   101401 tagggggaaa atacgaggat tataacttta ttgtagctca tttaggttca ggaatatcga
   101461 ttgtagcaca taaacaaggc aaaatgattg atggaagtgg tggtaggtct gatggtccat
   101521 tttctccaga aaggagtggt ggattacttg catatcctct tatagaattg tgttactccg
   101581 gaaaatatac tcatgatgaa atggtcgcaa aagtaagttc gattggggga atgtacgatt
   101641 atttaggaac aaaggatatg atagaaattg aaaacagaat caaggagggt gatgaaaagg
   101701 caaaacttat aatggatgca tttatttatc aagtagcaaa agaaatttct atgtatggag
   101761 cttcactttc agggaatgta gatagagtta tcttgacagg agggatatct cactcagaaa
   101821 tggtagtcaa aggagtagca gaaaaagttt catatctagc tccaatagag atagtaccag
   101881 gagagatgga aatggaggca cttgctctag gggcacttag agtacttaat ggagaagaaa
   101941 tagcaaaaac ttattaatat ttaggagaaa gagtatgtta aaagatttta ataatttatt
   102001 agaagaggct aaaaagcttg aacctgttat tgtaagtgtt gctgttgcag aagacaaaga
   102061 agtattaaag gctgtgaaat cagcaacaga tttaaacatt ataaagccaa ttcttgtagg
   102121 agacaaggat aaaatagaaa gtatatcaag agaaattgga ttaaaaggtc atgaaataat
   102181 aggttgtcaa aatcccgatg aatcagttaa aaaagctgta gagatagtta aaaataagga
   102241 agctaaagtt cttatgaagg gattagtaaa tacaagtgtc tatatgagag ctatattaaa
   102301 taaagaaacg ggtcttagaa caggaagatt attaagtttg cttgcagtat atgaattacc
   102361 tcaatatcat aaacttcttt attgtactga tagtggaata aatgtatcgc caaacttaaa
   102421 tcaaaaaaaa gatataatga caaatgcact tcttactatg aaaagtatag gcatggaaaa
   102481 tcctaaaact gcgatactta ctgcaaatga aatggtagac cctaagatac aatctacagt
   102541 ggatgccaac ctacttgtag agatggaaaa atcgggagaa ataccaaagt gtatagtgga
   102601 aggtccaata gcatttgatg tagcatttga tgcacatgca gcagaacata aaggtattaa
   102661 aagtaatatt gctggtgatg ttgatttatt agtatttcca aatatagaag cagggaatat
   102721 attaggaaag tcatggctta gatttaataa agctaagtgg gcaggtatag ttttaggagc
   102781 aacaaatccg ataattttag gttcacgttc tgacacagct gaaataaaaa taaattcaat
   102841 agcattagcg tgcctagcat cacaataaga aattattatt aaggaggaaa aagtattatg
   102901 aaatatgcaa aaagaatgga tatggtaaaa gcttcagcta taagagattc tcaaaagaaa
   102961 atagctcaga aggtagcaag tggtggaact gttatatctt ttgctgcagg gcttcctgac
   103021 ccaaatttat ttccaataga agagataagt gaaataactc aaaaagtact taatgaaagg
   103081 ggaaaatttg ccctagcata tggacctact aaaggtgaag atgagttgtt agatctatta
   103141 gtaaaaagaa tgaaagaaga agaaaatatt gatacaaaag cagaaaatat tataataact
   103201 actgggtcac aacaagggat agcattaagt gctatgattt tattagaaaa gggagatgta
   103261 gtagttacag aaaatccaag ttacttaggt gcaataaatg catttagacc ttatgaatgt
   103321 gattttttag gagtagatac agatgaagaa ggaatggtaa cagatgattt agacaaatta
   103381 ttatctgaaa attctaacat aaaggtgata tatgtaatac caacatttca aaaccctaca
   103441 ggaaaaacat ggtctttaca aagaagaaaa gattttatgg aagtcgtgaa taaatatgat
   103501 gtcatagtaa tagaggataa tccttatgga gaaataagat ttacaccaga acctctacct
   103561 acacttaaat ctcttgatac taaagataaa gtattgtacc ttgggtcatt ttcaaaggta
   103621 ttatgtccag gatttagagt tgcttggatg tgtggtaatg tagacatcat agataaggca
   103681 gaacttttaa aacaaggtat agatttacag tcaaatcaat tttcgcaagt acaagtaata
   103741 gaatttttaa agaaatacaa cttaaatgaa catatagaaa aaataagagc agagtataag
   103801 aaaagatgtc tgctaatgtt agatgctatg aagaaacatt tcccagagga agctaaatat
   103861 acagaaccag atggaggaat gtttatatgg gttgaacttc ctgaaagtat aaatgtagat
   103921 gatttattag ataaagccat tgatgctgga gttgcttatg tttctggaga gtccttcttt
   103981 gcaaataatg gtccaaaaaa tactatgaga cttaactata caacaatgtc agaagaacaa
   104041 atcgttaaag gtgttgagat acttgcagaa gttataaaaa aagaactcaa ttatgcttgt
   104101 gaataaatat aaaaagtgag ggtttaaata tgggagaaaa agaaaacggt ataaagtttg
   104161 gaaagttaat gtttcaactt gttattatag caatatcttg ggaattagtt tatattatac
   104221 catttatcca atatacatta tatgatccaa ttctaaaagc attagaatgt acaaacactc
   104281 aactaggttt tctacttaca atttatgggt taggtaatat atttggagct cctataggag
   104341 gctggttagc agatagattt gattatagaa agataatttt aggttctgta tttcttaatg
   104401 gagtagtatc atttttattt gcatttaata tgaactatcc atttgcagtt gctacttggg
   104461 taggttgtgc aatcacatca ttagttatga actatccttc tatggtaaaa atacttagag
   104521 ttataggaaa agataatcaa ggtaaggttt atggatttaa tgaagctatg gttggagttt
   104581 ctggagtagt aatgggagca atattcttat atatttatac atgctttgca actcctacat
   104641 tgggtatgag atgggtaatg atatctttag gaatattatc aatagcaatg tgtccagtat
   104701 tatggtttgt aattaaagat gtagatatta aagaagaaag agaagaagca ggtgaaaaaa
   104761 tgtctgctgg tgattttata acagtactaa aatcaccaaa tacttggcta gtaggaataa
   104821 gtatattctg tgtatattca ttcacagtta caatgtctta ttttacacca tatataacat
   104881 ctgtacttgg aggttctgta gcattatctg gtgcattagc aataataaga cagcatggtc
   104941 taaaattatt tggagcacca tttggaggat attgtgcaga caaattaaaa tctcctacaa
   105001 aagtactttt accaatatat gtatttggta tagcagtaat agttttattc ctagtattac
   105061 ctgcatcaac tccaatgact atattcatag ctttaacatt tgtagtaggt atattaggtt
   105121 acatgggaaa aggtatatat tatgcagtac aagatgaagt aaaagttcca gttaaatatt
   105181 cagcaactac tataggtata gctgcagctt taggattttc accagatgta ttccaatttg
   105241 cattaatagg acactggata gatacttatg gcaataaagg ttacacatat acatttatat
   105301 tccaaatagc aattctagtt attggaatac tatcttgttt atatatatta aaggttaaaa
   105361 agagaagagc aagtaaatta gaagcttaaa tattcaattt ggtaattaag tatatataaa
   105421 tacaatactt attttgatga atgtgattgt ataaataaca taaaaaatat caatagatta
   105481 agttttataa taatgtttag agaataaagt ataaaaatca aaatgttatc aagttttcta
   105541 ggttttaaca taaagttacc cctgaaggtg taaaattgag tggcaattat tatctatttt
   105601 cttacctaca taaacctatt taatttaaat tctaagagat tttaaaaata gatggtagtt
   105661 gtactcaatt ttaaacctca taataaatac gaaaatttaa aatctaacta gatactattt
   105721 aattatatat taataaatat atattgtact atttatataa taataatttc aggcttttca
   105781 ttatatgtat tccaatttat attgtttgat tattattcaa acacacgtcg ttaaaaattt
   105841 tataaattta tgtttagata tgattaat
//
LOCUS       DAGQVA010000004        96672 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.004, whole genome shotgun sequence.
ACCESSION   DAGQVA010000004 DAGQVA010000000
VERSION     DAGQVA010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 96672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96672
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.004"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            102..218
                     /gene="rrf"
                     /locus_tag="MIV85_000352"
     rRNA            102..218
                     /gene="rrf"
                     /locus_tag="MIV85_000352"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            337..528
                     /locus_tag="MIV85_000353"
     CDS             337..528
                     /locus_tag="MIV85_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBY2959729.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            683..2092
                     /locus_tag="MIV85_000354"
     CDS             683..2092
                     /locus_tag="MIV85_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBY2959730.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILENLYKM
                     DTTEILGTDNLHFPEGIIKNSQEKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEVSEETNVLKGISISNVIDIVDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPSFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIRTFKNNVDSNINIYDTNDKTKIFISSKNMGLTGYELESILRNKYNIQV
                     ELSNYYGVLLICTIGNIAKDFSSLETALNNVIKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            2213..2902
                     /locus_tag="MIV85_000355"
     CDS             2213..2902
                     /locus_tag="MIV85_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBY2959731.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSEKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKSMER"
     gene            2905..3840
                     /locus_tag="MIV85_000356"
     CDS             2905..3840
                     /locus_tag="MIV85_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBY2959732.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3837..4730
                     /locus_tag="MIV85_000357"
     CDS             3837..4730
                     /locus_tag="MIV85_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBY2959733.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4808..5554
                     /locus_tag="MIV85_000358"
     CDS             4808..5554
                     /locus_tag="MIV85_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBY2959734.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSVKLNGLEERVKIINED
                     IKYIDKVLDVNGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5555..6388
                     /gene="rsmI"
                     /locus_tag="MIV85_000359"
     CDS             5555..6388
                     /gene="rsmI"
                     /locus_tag="MIV85_000359"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBY2959735.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHKFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRKISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6411..7115
                     /locus_tag="MIV85_000360"
     CDS             6411..7115
                     /locus_tag="MIV85_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBY2959736.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYTEKGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7303..7731)
                     /locus_tag="MIV85_000361"
     CDS             complement(7303..7731)
                     /locus_tag="MIV85_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBY2959737.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7768..9198)
                     /locus_tag="MIV85_000362"
     CDS             complement(7768..9198)
                     /locus_tag="MIV85_000362"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBY2959738.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9330..9914
                     /locus_tag="MIV85_000363"
     CDS             9330..9914
                     /locus_tag="MIV85_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBY2959739.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9930..10451
                     /locus_tag="MIV85_000364"
     CDS             9930..10451
                     /locus_tag="MIV85_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HBY2959740.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10517..10763
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10847..12784
                     /gene="metG"
                     /locus_tag="MIV85_000365"
     CDS             10847..12784
                     /gene="metG"
                     /locus_tag="MIV85_000365"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBY2959741.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     EIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFRKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12814..13584
                     /locus_tag="MIV85_000366"
     CDS             12814..13584
                     /locus_tag="MIV85_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBY2959742.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFDIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13926..14357
                     /gene="phnG"
                     /locus_tag="MIV85_000367"
     CDS             13926..14357
                     /gene="phnG"
                     /locus_tag="MIV85_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBY2959743.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14372..14947
                     /gene="phnH"
                     /locus_tag="MIV85_000368"
     CDS             14372..14947
                     /gene="phnH"
                     /locus_tag="MIV85_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBY2959744.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQEDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGVREEFIERLSTINK
                     DYPIGIDLILVDKKGELAFIPRSSKLSWEVL"
     gene            14950..16035
                     /locus_tag="MIV85_000369"
     CDS             14950..16035
                     /locus_tag="MIV85_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBY2959745.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYIRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVDLLEEDEKKNRDFKDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKSEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSENLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            16055..16924
                     /locus_tag="MIV85_000370"
     CDS             16055..16924
                     /locus_tag="MIV85_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBY2959746.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAVSIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRNFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16917..17783
                     /locus_tag="MIV85_000371"
     CDS             16917..17783
                     /locus_tag="MIV85_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2959747.1"
                     /translation="MSKINDSKRLESIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILKLSDQKKRYIKNHFMGIVYQNPHLGLNLDFSNGGNIAEKLLMANLYNVEKIR
                     DRAKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17824..18537
                     /locus_tag="MIV85_000372"
     CDS             17824..18537
                     /locus_tag="MIV85_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2959748.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACNNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18538..19707
                     /locus_tag="MIV85_000373"
     CDS             18538..19707
                     /locus_tag="MIV85_000373"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBY2959749.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYIIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLDKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYREYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKLDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19711..20547
                     /locus_tag="MIV85_000374"
     CDS             19711..20547
                     /locus_tag="MIV85_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBY2959750.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGVTIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLFYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20548..21543
                     /locus_tag="MIV85_000375"
     CDS             20548..21543
                     /locus_tag="MIV85_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2959751.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLDVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21561..23249
                     /locus_tag="MIV85_000376"
     CDS             21561..23249
                     /locus_tag="MIV85_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBY2959752.1"
                     /translation="MITSKNKRRINDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYIENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     NFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVVGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYFLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNIVHFYSVCFITSNSSLKMLDR
                     EYELVAKSISIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23261..24328
                     /locus_tag="MIV85_000377"
     CDS             23261..24328
                     /locus_tag="MIV85_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2959753.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCGTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24811..24954
                     /locus_tag="MIV85_000378"
     CDS             24811..24954
                     /locus_tag="MIV85_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959754.1"
                     /translation="MDDDINMIAIRPEDIKVEFNRDFKDVDIKVREILDIEFRRFNYI
                     VTV"
     gene            25292..26359
                     /locus_tag="MIV85_000379"
     CDS             25292..26359
                     /locus_tag="MIV85_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2959755.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26551..27081
                     /gene="rnmV"
                     /locus_tag="MIV85_000380"
     CDS             26551..27081
                     /gene="rnmV"
                     /locus_tag="MIV85_000380"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBY2959756.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPKSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            27251..28120
                     /gene="rsmA"
                     /locus_tag="MIV85_000381"
     CDS             27251..28120
                     /gene="rsmA"
                     /locus_tag="MIV85_000381"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBY2959757.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCETEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EEIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            28186..29445
                     /locus_tag="MIV85_000382"
     CDS             28186..29445
                     /locus_tag="MIV85_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959758.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKEDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKIENYEDILFQEVEEEEYEELEEEDEEIEDNEESDRDEDSEEEEY
                     IIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSGDEEIEEFNNYKEIENYNRVKVQE
                     EYIDIEYDEEEEDEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQGE
                     SGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLGY
                     LNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFLR
                     YQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29596..30711
                     /locus_tag="MIV85_000383"
     CDS             29596..30711
                     /locus_tag="MIV85_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBY2959759.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGKVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAESRSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30897..31793
                     /locus_tag="MIV85_000384"
     CDS             30897..31793
                     /locus_tag="MIV85_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBY2959760.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31863..32660
                     /locus_tag="MIV85_000385"
     CDS             31863..32660
                     /locus_tag="MIV85_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959761.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVRVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32715..34067)
                     /locus_tag="MIV85_000386"
     CDS             complement(32715..34067)
                     /locus_tag="MIV85_000386"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBY2959762.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            34286..35164
                     /gene="purR"
                     /locus_tag="MIV85_000387"
     CDS             34286..35164
                     /gene="purR"
                     /locus_tag="MIV85_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBY2959763.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            35320..35598
                     /gene="spoVG"
                     /locus_tag="MIV85_000388"
     CDS             35320..35598
                     /gene="spoVG"
                     /locus_tag="MIV85_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBY2959764.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35811..37190
                     /gene="glmU"
                     /locus_tag="MIV85_000389"
     CDS             35811..37190
                     /gene="glmU"
                     /locus_tag="MIV85_000389"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBY2959765.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYSYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SVVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            37285..38235
                     /locus_tag="MIV85_000390"
     CDS             37285..38235
                     /locus_tag="MIV85_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBY2959766.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      39076..39161
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            39323..39844
                     /locus_tag="MIV85_000391"
     CDS             39323..39844
                     /locus_tag="MIV85_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBY2959767.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLNVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGKDGEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGDQLKDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            39995..41671
                     /locus_tag="MIV85_000392"
     CDS             39995..41671
                     /locus_tag="MIV85_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBY2959768.1"
                     /translation="MAKKVRIGDKLVEKGYITEDQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESITIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41683..42891
                     /locus_tag="MIV85_000393"
     CDS             41683..42891
                     /locus_tag="MIV85_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBY2959769.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTPVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILVSAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVSILVVSIF
                     MPMLSIYDAM"
     gene            42906..44618
                     /locus_tag="MIV85_000394"
     CDS             42906..44618
                     /locus_tag="MIV85_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBY2959770.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLILDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQLKAKQMKNILK
                     IVPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTADK
                     SSNNETKSNTKSDSNGDKTNNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFEDVKLHSIKSNAEDSTYTFSMTLYLKEGV
                     LTNE"
     gene            44611..45519
                     /gene="pilO"
                     /locus_tag="MIV85_000395"
     CDS             44611..45519
                     /gene="pilO"
                     /locus_tag="MIV85_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBY2959771.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVREYEHFYGVSTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTSYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45546..46112
                     /locus_tag="MIV85_000396"
     CDS             45546..46112
                     /locus_tag="MIV85_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBY2959772.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFMMTIVLSISYKVFNGITSAVKRQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKH
                     TEVYSVTRIQKNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQENHKNSNLNNKTYTFDVMSRIG"
     gene            46148..46675
                     /locus_tag="MIV85_000397"
     CDS             46148..46675
                     /locus_tag="MIV85_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBY2959773.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSK
                     GDVSLYDTPYEKITTIKDEDGNLIGKENITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46696..48234
                     /locus_tag="MIV85_000398"
     CDS             46696..48234
                     /locus_tag="MIV85_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959774.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSELEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEHILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPNSQEYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEVDKTEGISIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDSKKNIIGLGVEENSNSKYKVEAIVNFNLNIDTNVVGNYNIKDKILINHDISSY
                     KKVN"
     gene            48334..49416
                     /locus_tag="MIV85_000399"
     CDS             48334..49416
                     /locus_tag="MIV85_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBY2959775.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPENIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKSGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            49397..50179
                     /locus_tag="MIV85_000400"
     CDS             49397..50179
                     /locus_tag="MIV85_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBY2959776.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGILFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILIFGAIFSIIFNLLFKEIPVKDSIIGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     TSRIKGKEYNSVIPYGPFISIGALITILCGKQLLEFYFSMII"
     gene            50281..50931
                     /locus_tag="MIV85_000401"
     CDS             50281..50931
                     /locus_tag="MIV85_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBY2959777.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50945..51505
                     /locus_tag="MIV85_000402"
     CDS             50945..51505
                     /locus_tag="MIV85_000402"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBY2959778.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51522..54908
                     /gene="mfd"
                     /locus_tag="MIV85_000403"
     CDS             51522..54908
                     /gene="mfd"
                     /locus_tag="MIV85_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBY2959779.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGAENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54939..55934
                     /locus_tag="MIV85_000404"
     CDS             54939..55934
                     /locus_tag="MIV85_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBY2959780.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            56058..56597
                     /gene="spoVT"
                     /locus_tag="MIV85_000405"
     CDS             56058..56597
                     /gene="spoVT"
                     /locus_tag="MIV85_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBY2959781.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56717..58330
                     /locus_tag="MIV85_000406"
     CDS             56717..58330
                     /locus_tag="MIV85_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBY2959782.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58437..59885
                     /gene="mazG"
                     /locus_tag="MIV85_000407"
     CDS             58437..59885
                     /gene="mazG"
                     /locus_tag="MIV85_000407"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBY2959783.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59974..60252
                     /locus_tag="MIV85_000408"
     CDS             59974..60252
                     /locus_tag="MIV85_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBY2959784.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            60324..60566
                     /locus_tag="MIV85_000409"
     CDS             60324..60566
                     /locus_tag="MIV85_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBY2959785.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60628..60882
                     /locus_tag="MIV85_000410"
     CDS             60628..60882
                     /locus_tag="MIV85_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBY2959786.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60883..61416
                     /locus_tag="MIV85_000411"
     CDS             60883..61416
                     /locus_tag="MIV85_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959787.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61422..61706
                     /locus_tag="MIV85_000412"
     CDS             61422..61706
                     /locus_tag="MIV85_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBY2959788.1"
                     /translation="MNLRKKFSGQIIVVSLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61819..62739
                     /locus_tag="MIV85_000413"
     CDS             61819..62739
                     /locus_tag="MIV85_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBY2959789.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62829..65201
                     /gene="spoIIE"
                     /locus_tag="MIV85_000414"
     CDS             62829..65201
                     /gene="spoIIE"
                     /locus_tag="MIV85_000414"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBY2959790.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65552..67444
                     /gene="pepF"
                     /locus_tag="MIV85_000415"
     CDS             65552..67444
                     /gene="pepF"
                     /locus_tag="MIV85_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBY2959791.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67558..68523
                     /gene="galU"
                     /locus_tag="MIV85_000416"
     CDS             67558..68523
                     /gene="galU"
                     /locus_tag="MIV85_000416"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBY2959792.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            69023..70627
                     /gene="rho"
                     /locus_tag="MIV85_000417"
     CDS             69023..70627
                     /gene="rho"
                     /locus_tag="MIV85_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBY2959793.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70780..70980
                     /gene="rpmE"
                     /locus_tag="MIV85_000418"
     CDS             70780..70980
                     /gene="rpmE"
                     /locus_tag="MIV85_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBY2959794.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            71125..72018
                     /locus_tag="MIV85_000419"
     CDS             71125..72018
                     /locus_tag="MIV85_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBY2959795.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            72036..72884
                     /gene="prmC"
                     /locus_tag="MIV85_000420"
     CDS             72036..72884
                     /gene="prmC"
                     /locus_tag="MIV85_000420"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBY2959796.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYVENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72928..73992
                     /gene="prfA"
                     /locus_tag="MIV85_000421"
     CDS             72928..73992
                     /gene="prfA"
                     /locus_tag="MIV85_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBY2959797.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            74121..74801
                     /locus_tag="MIV85_000422"
     CDS             74121..74801
                     /locus_tag="MIV85_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBY2959798.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74830..75870
                     /locus_tag="MIV85_000423"
     CDS             74830..75870
                     /locus_tag="MIV85_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBY2959799.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75887..76336
                     /locus_tag="MIV85_000424"
     CDS             75887..76336
                     /locus_tag="MIV85_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBY2959800.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            76353..76805
                     /gene="rpiB"
                     /locus_tag="MIV85_000425"
     CDS             76353..76805
                     /gene="rpiB"
                     /locus_tag="MIV85_000425"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBY2959801.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76841..77470
                     /gene="upp"
                     /locus_tag="MIV85_000426"
     CDS             76841..77470
                     /gene="upp"
                     /locus_tag="MIV85_000426"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBY2959802.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77771..78586
                     /locus_tag="MIV85_000427"
     CDS             77771..78586
                     /locus_tag="MIV85_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBY2959803.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDTVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78812..79249
                     /locus_tag="MIV85_000428"
     CDS             78812..79249
                     /locus_tag="MIV85_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBY2959804.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79434..79661
                     /locus_tag="MIV85_000429"
     CDS             79434..79661
                     /locus_tag="MIV85_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBY2959805.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79666..80052
                     /locus_tag="MIV85_000430"
     CDS             79666..80052
                     /locus_tag="MIV85_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBY2959806.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            80055..80759
                     /gene="atpB"
                     /locus_tag="MIV85_000431"
     CDS             80055..80759
                     /gene="atpB"
                     /locus_tag="MIV85_000431"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBY2959807.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80828..81088
                     /gene="atpE"
                     /locus_tag="MIV85_000432"
     CDS             80828..81088
                     /gene="atpE"
                     /locus_tag="MIV85_000432"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBY2959808.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            81211..81708
                     /gene="atpF"
                     /locus_tag="MIV85_000433"
     CDS             81211..81708
                     /gene="atpF"
                     /locus_tag="MIV85_000433"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBY2959809.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81705..82250
                     /locus_tag="MIV85_000434"
     CDS             81705..82250
                     /locus_tag="MIV85_000434"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBY2959810.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            82267..83769
                     /locus_tag="MIV85_000435"
     CDS             82267..83769
                     /locus_tag="MIV85_000435"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBY2959811.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83797..84675
                     /gene="atpG"
                     /locus_tag="MIV85_000436"
     CDS             83797..84675
                     /gene="atpG"
                     /locus_tag="MIV85_000436"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBY2959812.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84688..86082
                     /gene="atpD"
                     /locus_tag="MIV85_000437"
     CDS             84688..86082
                     /gene="atpD"
                     /locus_tag="MIV85_000437"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBY2959813.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            86085..86345
                     /gene="atpC"
                     /locus_tag="MIV85_000438"
     CDS             86085..86345
                     /gene="atpC"
                     /locus_tag="MIV85_000438"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBY2959814.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86808..87188
                     /locus_tag="MIV85_000439"
     CDS             86808..87188
                     /locus_tag="MIV85_000439"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBY2959815.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            87203..87664
                     /locus_tag="MIV85_000440"
     CDS             87203..87664
                     /locus_tag="MIV85_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBY2959816.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87685..88275
                     /locus_tag="MIV85_000441"
     CDS             87685..88275
                     /locus_tag="MIV85_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959817.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            88290..89447
                     /gene="alr"
                     /locus_tag="MIV85_000442"
     CDS             88290..89447
                     /gene="alr"
                     /locus_tag="MIV85_000442"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBY2959818.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89480..89767
                     /locus_tag="MIV85_000443"
     CDS             89480..89767
                     /locus_tag="MIV85_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBY2959819.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89736..90119
                     /locus_tag="MIV85_000444"
     CDS             89736..90119
                     /locus_tag="MIV85_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBY2959820.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            90290..91117
                     /locus_tag="MIV85_000445"
     CDS             90290..91117
                     /locus_tag="MIV85_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBY2959821.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            91110..92051
                     /locus_tag="MIV85_000446"
     CDS             91110..92051
                     /locus_tag="MIV85_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBY2959822.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVSVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            92474..93568
                     /locus_tag="MIV85_000447"
     CDS             92474..93568
                     /locus_tag="MIV85_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959823.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            93794..94210
                     /locus_tag="MIV85_000448"
     CDS             93794..94210
                     /locus_tag="MIV85_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959824.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(94392..94961)
                     /locus_tag="MIV85_000449"
     CDS             complement(94392..94961)
                     /locus_tag="MIV85_000449"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBY2959825.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            95115..96272
                     /locus_tag="MIV85_000450"
     CDS             95115..96272
                     /locus_tag="MIV85_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBY2959826.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
BASE COUNT        38804 a        10431 c        17761 g        29676 t
ORIGIN      
        1 atatatgtgc agtttttaga gtgttaactc taaagaaact agtgttacta gattctaaaa
       61 aattattaaa aacttaatag aaatattaag cataaagatt atgtggttac aatagcagag
      121 aggatacacc tgttcccatt ccgaacacag aagttaagct ctctagcgct gatggtactt
      181 ggtgggaaac tgcctgggag agtaggacgt agccacgtaa tttttttatt ttttgtcaaa
      241 aaaaacaaaa aatacgtatt tcttttttca tttcgggaaa actaaacaca ggaattatgg
      301 actttataaa aatttaattc ttgaggagtg atataagtga aaaaagttgc tttaatttta
      361 gctataatag gtgcacttaa ctggggtgca attggtattc taggtacaga cttaataggt
      421 agtatctttg gtggaacata tgaaatggta agtagaataa tatacttcat tgtaggttta
      481 gctggattat acttaatacc aagtttaatg tctgatgata gagaataatt tatgctttta
      541 tgttaaatac ctcattctaa atgtttagaa tgaggtattt aattttataa aaatattaat
      601 ttgtttcttt tttaatggta aaatagataa gaattgaagt tttaaaaaga agtattatgt
      661 aaaaaaggag tactattaat atatgtttat tattaatgaa ttaaataaga ttgtaaatga
      721 agaagtaata tcttttcata tgcctggtca taaaaaggga caggtttata aaaagttagg
      781 atataaagat atactagaaa atttgtacaa aatggataca actgagatat taggaacaga
      841 taatttacac tttccagaag gcattataaa aaattcacaa gaaaaagcat caagagtatt
      901 taaaagtgat tatacttgct atttagtaaa tggtagtagc tgtggaatac aatctgcaat
      961 aatgtcagta tgtagcccta aaagtaaaat aataacaaat agagattgtc atcagtctgt
     1021 tataaatgga tgtattttag gagatataga tatagagtat gtgccttgtg aggtaagtga
     1081 agagacaaat gtcttaaaag ggatatctat aagtaatgtg attgatatag tagataaaaa
     1141 cttggatgca aaagcagtac tgcttactta tcctacatat tatggaatga catatgattt
     1201 agaatacata tgtaattatg cacatagcaa aaagatggta gtgatagtag atgaagcaca
     1261 tggtgcgcat ttagggctta gtgagaggct tcctaaaaca gctcttgaac aaggtgcaga
     1321 tatagttgta cagagtacac ataaaactct tccatcattt acacaatcgt caatgataca
     1381 tatacaggga gaccgagttg atatagataa aatattgaac atgttaagaa ttacagaatc
     1441 ttcaagccct tcatatttat tattatcttc tctggaatta gcagtagata tatatgaaaa
     1501 taaaggaaag gaattaatgg aagagctttt aaataatatt agaactttca aaaataatgt
     1561 tgattcaaat attaatatat atgacacaaa tgataaaaca aaaatattta tatcatctaa
     1621 aaatatgggt ttaacaggtt atgaactaga aagtatttta agaaataaat ataacataca
     1681 agtggaatta tctaattatt atggagttct tttaatatgt acaataggaa atattgctaa
     1741 ggatttctct agtttagaaa cagcattaaa caatgttata aaggaagact ttaaatttga
     1801 aaagttagaa aataaaaaat accctgttgt tattccaaag aaaatattaa cacctagaga
     1861 agcattttat aaaactaaaa aaagtgttaa aatatatgac agcataggta aaatttgtgg
     1921 tgaatgtata gtgccatacc cacctggaat aagtgtaata tctcctggtg aagtaataag
     1981 taaagaaata atagactatc taatgttttg tcattctaaa ggtatgattg tgagtggatt
     2041 gaaagatgta gatttaaatt ttatacaagt aatagattta gaagacattt aaaaattatg
     2101 atataaaagt agatagtttg aaattgtgaa gagaaataaa tagactgctt atatagagct
     2161 atctaataaa agtactaaaa aagtaaaaag tgtttgtatg gaggatatga aaatgaaagg
     2221 taagctaata attatagaga gtggttcaga tgcaagtgga aaggctactc agacagaaat
     2281 attatatgaa agattaaaaa aagaaggcta tatgattaaa aaggtagaat atccaaatta
     2341 tgaatctcca tcatctgcct tggtgaaaat gtacctaaaa ggagactttg gtaaaaatgc
     2401 atcagatgta gacccatata tagcatcaac tttttttaca gctgataggt atgcatcatt
     2461 taaaaccgat tgggaggagt tttacaatga aggtggaata attatcgcag atagatatac
     2521 aacctctaat atggtacatc aggcctctaa aatggatatt tgtgatagag aagagtattt
     2581 aaattggtta gctgattatg aatttaattt atttaagata ccacaacctg attgtgttat
     2641 atttttagat gttcctattg aatttagtga aaagcttatg gagaatagaa aaaataaaat
     2701 tacaggggaa gaaaaaaaag atattcatga aagtgatata gagtatttag agaaatctta
     2761 taacaatgct ttatatatag cagataaata tgattggaaa aaaataaatt gtgttttaga
     2821 taacaaatta agaagtattg aaagtataca taatgaaatt tataaaatag ttcttgattc
     2881 aataaaatct atggagagat aaatatgtat tttgaaaata ttatagggca agattttgca
     2941 aagaaatatt taacaaattc tataaagaaa aataaactta ataatgcgta tatgtttgaa
     3001 ggaatggatg gaataggaaa aaagaaattt gcagatgaat tatcaaaact attacttgat
     3061 tatgaaaatc ttgaaaatag tccagactat gtactcataa aaccagatgg aaatagcata
     3121 aaaatagctc aaatcagaaa tttacaatca gatatagtaa taagacctca taaagactat
     3181 aaaatatata taatcaataa tgctgaaaaa atgactgtgg aagcccaaaa tgcactttta
     3241 aagacgctag aggaacctcc aaactatgct ataataatct tagtcacaaa caacaaggaa
     3301 tctttattag aaactataaa atctagatgt gatataataa agttctcacc tataccaatt
     3361 gaggacttaa aacgttattt gataaataca ggtatagaag aagaaagagc tcaattattg
     3421 gctatttttt cgagaggaag tattgagaat gctctaaatc tatctcagtc ttctgagttt
     3481 tcaatgatga gagaagatat acaacaatat attcagataa tgttagataa aaacatagta
     3541 gagattttaa atataccaaa taatatggaa aaatatagag gtaagattat agctttatta
     3601 gatatgatga taaactattt tcgggatatc atcctattaa aagaaaatgt aaacaagaac
     3661 atgttaataa atgtagataa gctagttttc attcaaaata tgagtggaaa aattagttat
     3721 tctcaattgt ccaagattat tgatataata gaagatgcaa agagcaaaat aaaaagcaat
     3781 tgcaatttca atataagcat acaagttatg tctttaaata tatacgaggt gattaaatga
     3841 taaagatagt aggtataagg tttaaaagtg ctgggaaaat atattatttt gaccctgttg
     3901 attttaatat agagcaagat atggatgtag ttgtagaaac tgcaagaggc ttggagtatg
     3961 ggaaagtagt cgttggtcca aaagatatgg atgaaagcga attagtttct cctttgaagc
     4021 caattataag aatagctaca gaagaagata aaaaagtata tctagaaaat aaggaaaagg
     4081 caaaagaaac ttttgagtta tgccaacaaa aaataaaaga acatgagtta acaatgtttt
     4141 taatagattg tgagtatacg tttgatagga ataagttgat tttttacttt acagcagaag
     4201 gaagaataga ttttagagaa ttggtaaaag acttagctgc tatatttaaa actagaatag
     4261 aacttagaca aataggtgtc agagatgaag ctaaatctat aggaggtcta gggccttgtg
     4321 gtagaaaact ttgttgttca tcttggttag gtgattttca accagtttca ataaaaatgg
     4381 caaaagacca aagtctatct ctaaatccaa caaaaatatc tggaatatgt gggagattat
     4441 tctgttgttt aaaatatgag catgatgtat atagtgaggc aatagaaaaa atgcctgttg
     4501 taggtgcatt ggtgcaatca gatgatggaa aaggaaaagt tgtagaagta aatcctttat
     4561 tagaacaaat taaagtggaa tttcaagaca agacagtaaa gatatacaca agagaagata
     4621 taaaaatact tagagagcct aaaaaatgtg atggctgtgg tggtaaatgt aaggataatg
     4681 atggattaga tgaagccaca ctaagagagt taaagaaatt agaagattaa atttaaggta
     4741 gggcttttcc tacctttttt aaagcaatta atgcttaaag ttattaatat ttgaggagaa
     4801 tttatatatg caattaaaag attcagaaag aatagatgat ttacaattaa aaggtcttaa
     4861 aattatacaa gatactaatg gtttttgttt tggtatagac gcagttttat tagctaattt
     4921 tactaaaata aaaaaagatg ctaaagtagt agatttgggt actggaactg gcattatacc
     4981 tattttgata gctggaaaaa gtgaagctaa aaaaattatt ggtgtagaaa tacaagaaga
     5041 tgtatatgaa atggcaactc gttctgtaaa attaaatgga ttagaagaaa gagttaagat
     5101 tataaatgaa gatataaaat acatagacaa agtcttagat gtaaatggct accatgtagt
     5161 cacatcaaat cctccatata tgcatattga tggaataaaa aatccaaatg ataaaaaagc
     5221 aatatcaaga catgaagtaa ggtgtaattt ggaagatgta attagagctg catccagatt
     5281 ggttatgccg agaggaaaat tcttcatgat acatagacca acaagattgg ttgatataat
     5341 aactttaggt agaaaatata aattagagcc aaaggttatt caatttgtgc atccaagacc
     5401 tcaaaaagca ccgaacttag ttttggttca atttgtaaaa gatggaagac cagagcttaa
     5461 aatattggac ccattgtatg tttatggaga agatgggaat tatacaaaag aattaaaagc
     5521 aatatataat aataaagata taggagagtt gtaaatgagt gggaaattgt acatatgtcc
     5581 aacaccaata ggaaacctag aagatataac atatagaact ttaagaatat taaaagaagt
     5641 agacttgatt gcagcagaag atacaagaca tagtataaaa cttttaaatc attttgaaat
     5701 ctcaaaacca ctaactagtt atcatgaaca taataaggat tcaaagggag attatttgat
     5761 aaataaacta attgatggtg aaaatatagc tctgataagt gatgcaggta tgcctggtat
     5821 atctgaccca ggagaagaga taataaaaca agctatacaa aataatatag agatagaagt
     5881 attgccaggt gcaacagcat ttgtaacggc tttagttggc tctggtatgg acacacataa
     5941 atttgttttt gagggctttt tagatagaga taaaaaagtt aggaaagcac aattggaaga
     6001 attaaaggaa gaaagtagaa ctataatttt ctatgaatca ccacatagat tgaaggatac
     6061 actaaaagat atgcttaaaa ttcttggtaa taggaagatt tctataaata gagaacttac
     6121 aaaaaaatat caagaaataa taagagaaaa tatagaaact accataaaaa tatttgagga
     6181 aaaagaagta agaggagagt ttgtattaat agtagagggt tttcatggtg agaagtcaaa
     6241 gaaagaaaat tatgatgggc ttacagatag ggaatatgtt ttaaaactaa ttgaaagtgg
     6301 tatgaacaaa aaagatgcaa taaaaatagt ttgtaaagat agaaagttaa agaaagatgt
     6361 ggtttataaa caagttttag atttataaaa cctgaatctg aggtgatttt atggaaatag
     6421 gaaaaattat aatagagagt ttaaagaggg aagatacaca taaaatattt atagaattag
     6481 ataataagca tgaattagaa aaaataattc ctaaaataag ctgtatgaag tctgtaggtg
     6541 aatgtaaata tcatgtagta aattgttttg aacattctat aaatgcatta aaagaattag
     6601 aaatagtatt aaatgataag gatttttttc caatacatct aagaaaacat gtgtcaaact
     6661 atttaaacac atatactgaa aaaggaataa ataagttaca tgtattaaag ctgggaacat
     6721 ttttacatga tataggtaag cctgacagta tgactttaga tgaaacagga agagttcact
     6781 tcacaaatca tgaaaaaata ggtgctcaaa taattgacaa tatggggata aagttggagt
     6841 tatcaacaga gacatataga cttataagta aatatgtaag atatcatatg atacttttgt
     6901 ctctgtataa gaaaaatgat ttgagtagga aagaattaat taatgtattt aacttggtag
     6961 atgaggacac tataggtgtg ataatgcttg ggtatgcaga tatagtgtct acagtaaaat
     7021 tattgggcaa gagtggagaa gtgagtgtat taaagacata tatggaatat attttaacaa
     7081 attatttgta taagagtaat tatacacatg tataaattta gttaatataa ttgagtttta
     7141 gatgattaat taaagtctga aatacacgga tttcaaaaac ataaaagaag ttgtctttgt
     7201 tgtaaaatta tgaaagacaa ctttttttat atcaaaaatt gaaattttat taaggatact
     7261 taatggtcta ttaattaata aaccattagt atttaattta tattacaata ttgattttgc
     7321 ttgtattggc gttgatagta taacagaggt cttagtagaa ccaattttct ttatagtatc
     7381 aatcacattt tctagctcgt acatatcttt tacaattact tttaaaagta agcaatcatc
     7441 acctgttata tggtgacatt ctacaatcct agggtccttt gcagctgact caataaattc
     7501 tgtatatcca ttgcttggaa gagaaatatg gataaatgcc tttataactc tacctaatga
     7561 atctgggttg acaatagctt tatatccttc tataacacca gactcttcta atcttttgac
     7621 tctttctgaa actgcaggag aagttaaacc aactattttt cctaagtcct tcatagaaat
     7681 tctcccatca tcctgtaaaa tttctatgat tctgtaatct gtaacatcca taaataaaca
     7741 gtccccctta aataaaaata attaatgcta taaaactttt ttagaatcta tcatttgtgt
     7801 ttttaaatac caaagatttc tagataaatc aaccttataa atgtgtggtt ttgaaagtct
     7861 tttgtattgt tcccagatag tacttaattc atattgtaca tgatttttta tttcaagaac
     7921 agctttttta ttatatttgc atctgccttt tatatacaat ggtttaagaa gctctttaac
     7981 tttgtaattt gtaaatacct ttgttttcca tgtataagta ggatggaaga tttctaaagg
     8041 tttagactca tctataactt catcatgtaa cataatcaaa tctgcctctg ccttattgtc
     8101 ttcgttatat attcttataa ccttcttgta accaggatta tttatttttt ctggattctc
     8161 agaaatcttt atcttaggtt caagaactcc tttttcacaa gatgcagcta atttataaac
     8221 tcctccaaga gaaggtgaat cgaaagatgt aatgagcttt gtacctactc cccatgaatt
     8281 tatagtagct ccttctgctt taagtgatgt tatggtatat tcgtctaggt cattagatgc
     8341 agtgatgctg atatctgaaa agccagcgtt atctaattgt tttttagctt ctttagataa
     8401 ataagctaaa tctccagagt caagtcttat acccataggt ttgtatcctt tttcagaaat
     8461 atttttgaat acttttattg cattaggaac cccactgttt aatacatcat aagtatctac
     8521 aagtagtagg catttatctg gataaacatc agcatatgct tggaatgctt caagttcatt
     8581 atcaaatttt tgtacccaac tgtgagcttg tgtaccaatt ataggtatat caaacatttt
     8641 ccctgctagt acgtttgcag ttccagcaca accaccaact acagcagccc tagctccata
     8701 tatccctgca tctggacctt gtgcacggcg taatccaaat tcaaatacag ggtctccttg
     8761 agctgcaaag caaactctag aggctttagt agcaataagg gactgaaaat taactattgt
     8821 taacaatgct gtttcaataa gttgagcttg atataaaggt gccttaacag taattaatgg
     8881 ctcattaggg aacatgatag ttccttcctc aacagcatat atatctcctg tgaatttaaa
     8941 ttcttttaaa aattttaaga acttatcaga aaataaattt aagtttttta agtactctaa
     9001 atcttcatct gaaaaatgaa gattatctat gtattcaaca acctgatcaa taccacaaac
     9061 tatagtatac cctccatcac aagcgttttt tctaaaaaac atatcaaata caacaatgtc
     9121 ttcatgaata ttcttttcaa aatagccatt taacatagta agctgatata aatcagtaag
     9181 aagtgttaga tttctcatta tttctctcct taattattat taaatattaa aaattgtaaa
     9241 aactcccaca cttatactaa aacataatat agtacaactt tcaagtataa agtattacct
     9301 aactatcata aaattattta aagaggagga tgattataat aggaaaaata tggttttata
     9361 tggtatcgat aggaataata ggaagcttga tttctaaaaa tatgggagaa ttaaataaag
     9421 ttatattaag tgaaacatca aaaggcatag aatttgcaat aagtctagct ggtatcatgg
     9481 cactttggat ggggataatg aatatcgcaa aagagtcagg cttaattgaa aagataggtc
     9541 aaaaattaaa tcctataatg agaagattat ttccttctat tccaaagggt cataaagcaa
     9601 tgtcttatat agttatgaat attgctttaa atatgttggg tgctggaaat ggtgcaacag
     9661 catttggttt aaaagcaatg agtgaacttc aaactttgaa taacaagaaa gatacagcca
     9721 ctaatgatat gattatgttt atggtaatca atatatcatc tatacaaata attccattta
     9781 ctataatcaa attaaggatg gatatggggg ctcaaaatcc aagtgaaata atttttacga
     9841 ctttatttgc aaccataata tctacagcag tagcaataat aacatgtaaa ttttttcaaa
     9901 gaagatatag ataaagggga tgtagataca tggagatatt ttcaaactta cttataccaa
     9961 taataattct gtacatagta gtttatggta aatataaaaa aatagatgta tatgatagtt
    10021 ttgtaaaagg agcgattgat ggattaaaag cagcatggga tatcctacca tatataatag
    10081 gtatattttt ggcaatagga atattcaaaa ctggtaaagg tcttgatatg ttagaatggc
    10141 tatttacacc aatagcaaat atgatgagta taccaaaaga attaataggt ctaataagtg
    10201 taaaaccttt atctggaagt ggtgctttag ggatgtacag tgaacttgca aatagagttg
    10261 gaataggaag tttagtagaa aaaatgggtg ctacgattgt aggttcttct gagactattt
    10321 tttacacaat ggcaatatac tatggaagtc ttaagataaa aaatactaga catacattat
    10381 catgtgctat gattagccat gttgcaggtg tcatagcagc tgtttttatt tgctatgtaa
    10441 tatttgtata atttgttgac aatatgggaa aaattttata atatagtgat tatatagaaa
    10501 caaatagtaa tacaaattat aagctatgaa aagaagagta aataaaggtt ttttctatca
    10561 gagagctagg ttaggtgaaa gctagtgtca aaagctttat tgaagatggt cttggagctt
    10621 tttatctgag caagtgtgct agggtaaaac ggttggacac gttatagtct actaaggtat
    10681 ctataaaatg tttctacatt tcatgtgaaa cataactatt atagatgaat tagggtggta
    10741 ccgtgaataa tctcgcccct atgttaactc ataggaggcg attttttatt atttaaatga
    10801 aagaatcata tgattacgaa cgataaaaaa ttaggaggta aataacatga gcaaaccgag
    10861 tttttatgta acaacaccaa tatactatcc aagtggagga ttacacatag gacatactta
    10921 ttcaacagta gccgcagata caatagctag attcaagcgt ttctgtggat atgatgtaaa
    10981 gttcttaaca ggaacagatg agcatggtga aaaaattcaa aagaaagcca tagaacaagg
    11041 aatgtcagag atagagtatc ttgatggaat gataaaagat ataaaggcct tatggaatac
    11101 tatggatata tcttatgatg attttataag aactacagaa aaaagacata cagaaataat
    11161 acaaaagata tttactaaac tatatgagca aggtgatata tataaaggtg aatatgaagg
    11221 tagatactgt actccttgtg agagtttctg gacagaatct caattactag aaggaaataa
    11281 atgccctgac tgtggaagag aaacatattt agtaaaagaa gaatcttatt tctttagatt
    11341 atctaaatat gaagatagat tgaaagagtt atttaaagat gatagtttct gttttcctgc
    11401 tgctagaaaa aatgaaatgg tagcaaactt tttagacaaa ggattagaag atttaagcgt
    11461 aactagaacg acttttgact ggggtataaa agttcctttt gatgaaaaac atgtaattta
    11521 tgtgtgggta gatgctttat gtaactatat aacagcatta ggttatatga ctgataatga
    11581 tgaagaattt agaaaatatt ggcctgccaa tgttcaaata gtaggtaaag aaatagtgag
    11641 attccataca ataatatggc cagcactttt aatggcttta ggtctagaag ttccaaaaca
    11701 agtatttgga catggatgga tactgtttgc tgatgataaa atgagtaaat caaagggtaa
    11761 tgtggtttat ccagaaccta taatagaaag atatggaata gacacactta agtacttctt
    11821 attaagagag tttgcatttg ggcaagatgg aagttatact catagaaatt ttgtaacaag
    11881 aataaattat gatttagcaa atgatttagg gaacttaata agtagaactg tagctatggt
    11941 tgaaaagtac aataatggta taataccaac agcaaaagtt tcaactgatt ttgatgctga
    12001 cttaaaagag caagccgttt caactagaga aaactttgaa gctgaaatgg ataaaatgca
    12061 attccatgaa gcattagaga gtgtatggaa attagttaga agaactaaca aatatataga
    12121 tgaaactatg ccttgggcac tagctaaaga tgaaacgaag aaagatgaat tagacacagt
    12181 tttatataat ttatgtgaat ctataagaat aatcgcaaca ctgataaatc ctataatgaa
    12241 tgagactgct aataaaatat atgaacatat aggaataaaa ggtcaagatg atataactac
    12301 atgggaaagt acaaaaacat ttggtcttat tggagaaaat gtaaaagtat ttaaaggtga
    12361 acctttattc ccaagattag atgtagaaaa agagatagaa gaattaacta aaatgttctc
    12421 tgggaaacct ccagtagaag aaaaaccttt agagcataaa gaagaaatta ctattgatga
    12481 tttagacaaa atagagctta gagtagggaa aataataagc tgtgaaaaac atccaaaagc
    12541 aaataaatta ttagtatcac aagttaagat tggaccagaa acaagacaaa tagtatcagg
    12601 aatagctgaa tactataagc cagaggattt agtaggaaaa gaggttacag tggtatgtaa
    12661 cttaaaacca gttaaattaa gaggtgtaga atctcaaggt atgatattag cagcaggtga
    12721 tgatggagac ccatatgttt taccatttac acaaggggct aaagatggat gcgaggttcg
    12781 ttagtaggca attaaatagt aaggagatta aagatgttat ttgactcaca tgcacattta
    12841 aatgatgaaa gttttgatga agatagagat gaacttattg gttcattaaa agataaaggt
    12901 gtagatttgg ttgtaaatcc aggagcagat atagagacgt cgataacagc aattgaactt
    12961 gcgaaaaaat acgactttat atattcagca gttggggtac atccacatga tgtatcaaaa
    13021 ctagatgata cagcaataga aactctaaga aaacttgcaa ctgagaatga aaaagttgta
    13081 gctattggag agattggatt agattattat tatgattatt ctccaagaga agaacaaaaa
    13141 gagtggttta agaagcaaat tgaattagct aatgagctaa aacttccaat aataatacat
    13201 gatagagatg cacatggaga tacttttgat ataataaaga atactaaaaa tcctgaaata
    13261 ggatgtgtac ttcattgtta tagtgggaat gtagagttag ctagagaata tgttaagatg
    13321 ggttgttata tatcaattcc aggcacggtt acttttaaga ataataaaaa aactagagaa
    13381 gtagtaagag aaatacctct agaaagatta ttcatagaga ctgattcacc atatatgtca
    13441 ccagagccac atagaggaaa gagaaacaat ccttctcaag tatcttttgt tgctgataag
    13501 atagcccagg aaaaagggat atcttatgaa gaagtatgta gagttacaaa agaaaatgca
    13561 aagaaatttt ttaatataaa atagacaaat taaatcttat aatgatatat ataataagtc
    13621 attataagta taggatgaga gtgcctcaaa atgagttttt tagttcatga ggcactcttt
    13681 tttgtatgaa atcaaatata ttttcatcat ttcaacaatg aaaaagaagt ttatcatatt
    13741 ttgagacagt ttgtttgttt ttatttattt aattcatatt ttaaaatata ttttcttaac
    13801 attgttaaaa aagaatttac aagatattca ttagaattaa ctcaactcta atattcactt
    13861 aacttaagtt gtttattatc ttattaaaga gaagtaaacg aaaggtagat taaggaggct
    13921 aaattttgta tacagttgat agtactaaga tattgataaa tatgaactta gagaaactag
    13981 agaagatata ctcaatgata aaagatacat caagtatttc tataattaaa gaacctaact
    14041 tagctacagt aatggtaaga gctaatgaaa gtgtaaaaaa cacaacattt aatttaggag
    14101 agatattagt tactgaatgt agtgtaaagg tagatgaaag cttgggttac ggaatagttt
    14161 cagaaaacaa taataagaaa gccatttact tagcagttat agatgcagtt ttacatagca
    14221 ataatagtaa atttgatgag ttaaagaatt acataaataa aagtgtatat gaagagaact
    14281 taagatatga acaagagatt attgatgaat ttagcttgat taataaaacg aaagttcaat
    14341 tcaatgctat ggattaaata ggaggagaat catggtaaat tatacacaag aaatatatag
    14401 aaagatgcta gatagtgctt catttcctgg gaaattaaat aatatagata atataaatat
    14461 agaaaataat acaaaactat tgaatggagc aattggtata gcaatcactt tattagacca
    14521 agaagttacc ttctatatag aaaattatac tcaagaagat ataaaaaata taagagcact
    14581 tacaatgtca aatcaaatag attatagaaa atcagattat atatttttag atattaattc
    14641 agaagtggat atattacaga ttaaaatagg ttcttttgaa tatcctgatg aaagtgcaac
    14701 tatagtacat caagtaaatg atttatcaac gtactctcaa actaagtata taaagcttga
    14761 tttgagtggt cctggtataa aatctaaaaa tagtatatat ataaatggag ttagagaaga
    14821 atttatagaa agattatcta ccataaataa agattatcca ataggaatag atttgatttt
    14881 agtagacaaa aaaggagaac ttgcatttat accaaggtca tcaaaattaa gttgggaggt
    14941 attgtagaaa tggcttatgt agcagttaaa ggtggagaag aagccatatt acaggctaaa
    15001 aatatacttg agttttatag ggtaaaagga gatagcttgc ctatagatgt aaagcagatt
    15061 gaggaacaaa tgtcttatgc tgtagacaaa gtaatgtctg aaggaagttt atacaacaag
    15121 gaactatcag cattggctat aaaacaagct caaggtgata tattagaagc ctctttctat
    15181 ataagagctt taaggtcaac aatgcctaga attacatatt cagaacctat aaatacagaa
    15241 gagatgagaa taaaaagaag aatatcagct acttttaaag atataccagg aggtcagtac
    15301 cttggggcaa ctagagacta tgaaaataga atattaaatg tagacttatt agaagaagat
    15361 gaaaaaaaga atagagactt taaagatagt tttataaatg aattagaaac agtagatgaa
    15421 atccctgaat ttacaaaaat atctaatata tttagaaaag aaaacttatt acaagaggaa
    15481 gtttgtgaaa acaaatcgga agaagttatt gatgatatta caagaaatag tttaagattt
    15541 ccagtttcta ggtcagcaaa gttacaggca ttaactagag gtgaaagtgg agtagtgtca
    15601 ggttttgctt atgctattgt aagaggtttt ggtgatgaac atccatatat aagtgaactt
    15661 agaactggta atgtatttat aaaagtaaaa catcccatct atgaagatga agaaataata
    15721 ataggtgata tgctggttac tgaatgtgaa atagtttcaa aagcatcaca aaataagact
    15781 gaaaattcta aaactaattc ggaagataaa aataagatgt ctttaggata tggtctttgt
    15841 atggggaata atgagaataa ggctatatct atggccatac tagacaaatc tttggagcca
    15901 aatagtgaaa acctagcaca agatgaagaa tttgtattgc ttcatataga tggaatagat
    15961 tcattaggat ttatatctca ctttaagctt cctcactatg tagattttaa agcggatgta
    16021 gaaagaataa aatagtatat ggaggtaagt ttaggtgata tacaattatg gttttttaga
    16081 tgaaaataca aagaaggaaa taagaagaaa aatattaaaa gcagtttcaa tacctggtta
    16141 tcaagttccc tttggctcaa gagaattgcc aatagctaaa ggatggggta ctggagggtt
    16201 acaattaaca ctatcattaa ttggtaaaaa tgatgtagta aaagtaattg accagggaag
    16261 tgatgattct acaaatgctt gtaatataag gaactttatt gcaagtgtaa gtaatgtaga
    16321 aaccacaaaa gatacgttag aagctacatt gattcaaacg agacatagaa taccagaaga
    16381 aaaacttaaa tctaatcaaa tactaatatt tcaagtacca ataccagaaa cccttagaat
    16441 agtggaacct agtgaagtag aaacaagaag aatgcattca gaagaagatt atagtaggat
    16501 gtgggtatat ctttatgaag atatagttag atttaatgat atatctatag cagttgaata
    16561 tccatgtaaa gtaaatgata gatatttaat gaatccatca cctataccta gatttgatat
    16621 aaaaaaatta aatatgtcag acaatttatt cttgtttggt gcaggtagag aaaaaagaat
    16681 ttatgctatt cctccatata caaaggtaga acctttagag tttgaggatt ataagtttga
    16741 agaggaaaaa tttgaaggga aatactgtag tttatgtaac agtacaaata catttttaga
    16801 tgaagtatat gacagtgata ctaatgaaaa gtactatagt tgttcagata caagttattg
    16861 tgaaaaagtt agattaaaaa ataacagtat agatgtaaca ataggaggta cttggaatga
    16921 gtaaaataaa tgactctaaa agattagaaa gtatagacaa gcaagtatta ataggaagaa
    16981 atatcaatct tatttatggg gatgggtgtg aaaagtgttt tgaaagcaca ggatatgaaa
    17041 gtaataatat atgtaagtat tgtggttcta tagttgcatg taataatgta aatttagaac
    17101 tttatgaagg agaagtcctt ggaattgtag gtgaatctgg ttcaggtaaa agtactttat
    17161 taaaaatact gtttttccaa gaacatgcaa atagtggaga agtatatata tcccattaca
    17221 ataaagacac aaatatacta aagctttcag accaaaaaaa gagatacata aagaatcatt
    17281 ttatgggtat tgtgtatcaa aatccccacc ttggtttaaa tttagacttt agtaatggtg
    17341 gtaatatagc agaaaaatta ttgatggcaa atttatataa tgttgaaaaa ataagagata
    17401 gagccaaaga acttttaata aaaactaata tacctgtaga aagaatagac cataaaccaa
    17461 aatactttag tgggggaatg caacaacgag ttcaaatagc aaaagctctt tcaaataacc
    17521 ctccaatatt gctattagat gaggttacaa caggtttaga tgtttctgtg caagcggaag
    17581 tattggattt aataagagaa atccaaagag aacttaagat ttctatgata gttgtatccc
    17641 atgactttga cgttataaag atgcttgctg ataggacaat tgtaatgaaa aatggaagtg
    17701 tgattgagtc tggtcttaca gaccaaataa tggaggaccc acaacaccca tatactcagc
    17761 aacttataaa ttcattgcta taaatatcgt ttgtaaataa gcaaaatggg ggtttttaat
    17821 aaaatgaaag aaactatact tgaagtaaat aattttagca aagactttga gttacatgca
    17881 ttgaacaaga ctataacggc atgtaataat ataagttttg aagtttcaaa aggtgagttt
    17941 ttaggaataa taggtaaatc tggagcaggt aagtctacca tattaaaaag tatctataaa
    18001 acatatatac caacaactgg agaaataatt tttaattcag aaatatatgg taatgtagat
    18061 ctggctaaaa ttggagaccg agaaatgata aatcttagaa agaaagaaat aggatatgta
    18121 tcacagtttt taaagacact tccacgaata actgcaattg aactagtagt acattcttta
    18181 attgagagtg ggtttgaaaa agattgttcg tatgatatgg caaaagatat acttaatcaa
    18241 tttgaaataa aggaaaattt atgggatgct tatccaaata atttttctgg tggagaaaaa
    18301 ttaagattaa atttagctca agctatggtt aaaaagccta gacttttatt acttgatgaa
    18361 ccaactgcat cacttgataa tcaatctaaa atatatgtaa aagaaaaaat gttggaactt
    18421 aaaagtcaag gaactacaat gataggaatt tttcatgata tagagtttat ggaaactgtt
    18481 atagataaga cctttactat ggcaaaaggg actataagtg aaagtggggt agcctagatg
    18541 ataaaactaa ttcataatgc aaatattgta ttagaagata tgatattaga aaatggccat
    18601 ttaatcatag agggagatac aataaaaaaa gtatcaaatg ataagattga ttacgcattt
    18661 gactttaatg agatagatga aataatagat gcaaaaaact tatatataat acctggtatt
    18721 atagatattc acagtgatgc cattgaaaag gaaatagagc caagaccaag tacattatta
    18781 ccatttaata tggcatttta tgagctagat aaaaaactac ctgcaaacgg aataactaca
    18841 gtttatcatt ctatatcctt aggggatgga gtaggagtta gaagtattga taactcttta
    18901 aagatgatta aaaatattga ttcatataaa aatatagata gtaagagtat aaatcataaa
    18961 gttcatttaa gatatgaagt gttgtattat gaaggtttag ataaggtttt agaactatta
    19021 gatgaaaata aaatagatta cttatcaata atggaccatt ctccgggaca aggtcagtat
    19081 acaaatccaa cattttatag agagtatgct actaaagtgt ggggagttac agaaaattat
    19141 gtagatacat ggttagatga tttagtaaat ctgcatgata atttagattg gaataaaata
    19201 gctaatatta taggtatagc caaaactaaa aatataaatg ttgcatcaca tgatgatgat
    19261 acattagaaa aactggattt cataaaaaat ataggcataa atgtatctga atttcctata
    19321 actcttgaag ttgcaaaaca ttcaaagaaa ttgggtgttc taacttgttt aggtgcaccg
    19381 aatattgtaa gaggtaaatc tcataataac aatttaaaag caatggatgc tatattggaa
    19441 gattgttgtg acattgtgtg ttcagattat cttccatcag ctatgataaa gtctatgtgt
    19501 atagttgcag aaagaataaa taatttaaat aaagcagtca gtttatttac ctcaaaccct
    19561 gctaaagcag ttggtatata tgatgaaaga ggtagtataa aagaaaataa aaaagcagat
    19621 ttagttttag tagatattga tagtgaatat ccaaaggttg taaatactat tgtaaacgga
    19681 aaaacagttt ataaaaggga ggtataaaga ttgttaacag agttacactg tcatacaagt
    19741 atatcagata ataattttac tactgaagaa ataataaaaa aagcagcaga aaagaatata
    19801 aatatcttag caataacaaa tcatgacaca ttatctggat tggatgaagc tcttgtgctt
    19861 ggagaacatt atggagtaac aataatacca ggtatagaaa tttcagctta tgattataaa
    19921 aatagaaaaa gagttcatat tcttggatat aacatagatt taaacagtca agaaataaaa
    19981 aatttgtgca atccaatggt atgtgacaga cataaagcat ctgttaagat ggtaaataaa
    20041 attatagatt tagggtacaa aatatctctg gaggatgtaa agaaatactc atcaaagact
    20101 ggaatattta aacaacatat aatgaaggct cttatagata aaggatatac agataatata
    20161 tattcaagtc tatataaaga attgtttcat agaggaaacg gcaaggtata tgtatcttta
    20221 aaatatgtgg attacagaga tgcaataaaa gctataaaaa attctggtgg aatttgtgtg
    20281 ttagctcacc caggtcaaat ggataatttt agcgctattg aagagatggt aaaagtagga
    20341 ttagatggaa tagaagtata tcatccatct cacaacaaag aattagaaaa agaatcgctt
    20401 ttttatgcta agaagtacaa tctagtggtc acaggaggct cagattacca cggattttat
    20461 tctcaacata attatgaact tggaagcaag agcttaaata aagaagactt atttaagttt
    20521 aggttagctt taggaggggt attataaatg tcttttttac aagtaaaaaa tgtaggtaaa
    20581 agttatggac aagttaaggt gttaaaagac atatccattg atattgaaaa aggggagttt
    20641 atttgcttat taggtccaag tggttgtgga aaaagtacac tgcttagaat aattgcaggg
    20701 cttgaggata aacatggtgg aaaaataata ataaatgata aagatatgac taattcacca
    20761 cctgaaagta gaaattttgg tatagttttt caatcatatg cattatttcc aaatatgaat
    20821 gtttacaaaa acatagcttt tggactagaa aataaaaaca taagtaaatc taatattgat
    20881 aaaaaagtta aagaagttct agacgttgta gaattgagtg gatatgagaa aaaatatcca
    20941 tcacaattat caggtggaca acaacaaagg gttgcattag ctcgtgcgat tgctttagag
    21001 ccagactttt tacttcttga tgaaccttta tctgcattag atgcaaaagt aagacttaaa
    21061 cttagggagc agattagaag tttacataga aaactaggca ttacaactat aatggtaaca
    21121 catgaccaag aagaagctct ttgtttagct gataagatgg ttgttatgaa tagaggagaa
    21181 ataatacaag ttggaacgcc aaaggaggta tataaaaatc cagaaacacc ttttgtagct
    21241 gattttatag gaacaataaa ttttatagat gatggtatta ataagatagc tattagacca
    21301 gaagatataa aagtagagtc caatagagat tctaaagata aggatataaa agtgggagaa
    21361 attttagata tcgaatttag aggatttaac tatagaatta cagttgagta tcgttctaag
    21421 caaatgaaat tagatgtagt ttccaaagtt gcagaacaaa tgaaactgtg cataggttct
    21481 aaaataaact ttaagatacc taaagaagga attgtacaat ataaatcaga gggatgtgct
    21541 taatagctag gggtgaataa atgataacat caaaaaataa aagaagaata aatgatagca
    21601 caatacaaaa atatttcttg attttttcgg taattgtact aatagtattt atattatttc
    21661 cattagtatc attattaaaa aatgcattta tggatacaag tggaaatttt ataggaattt
    21721 caaactttag taaatatatt gaaaatccaa gtcttatagc atcatttaaa aattcaattt
    21781 ttgtatctac agtctcatct ttaatatcac tatgtttagc atttatatat tcatacgcaa
    21841 taacaagaac aaacataaag tttaaaaatt tttttaaaac tatgggaatg tttccacttt
    21901 ttgcaccaac tatgctatat ggtatttcac ttatatacct ttttggaaat aagggaatct
    21961 ttacaacaat gggtttggaa gtaccactat atggtccatt aggaataatt atttctcaga
    22021 ttctatttac atttccacaa gcttttttaa tattatctgt agcactttcg atggctgatt
    22081 acagacttta tgaagcagca gatagcttgg gcgctagtga atttaagaaa ttttgcaaaa
    22141 taacaattcc tggtataaag tactcgttac ttagttcatt ctttgtatcc tttatacttg
    22201 catttacaga ttttggagca gctaaggtag tcggaggaaa ctacaatgta ctggccactg
    22261 acatatataa acaagtagtt ggacaattta acataccaat gggagctact gtctctatgg
    22321 taatgttaat tcctgtacta atagcattta cattagataa gatggcaagt aagaaacaag
    22381 gtatgaccat aactgcaaag tctatgccat ataagattaa agaaaataag tttagagata
    22441 gagtattttt aatagtatgt agttttataa cattgctaat ttttatttta atattcgttt
    22501 cagttgtagg ttcagttata aagttatggc catataattt aagctttaca atggaacact
    22561 atacatttaa aggtattttg ggaagtggaa taaaaacata cttaagcagt ttgaaaatat
    22621 caactttaac agcaatattt ggaactatat ttgtattttt tagtgcttat atgatagaaa
    22681 aagtggataa gtttcctaaa ttaagacaaa cagcttactt tttgtcaatg ataccaatgg
    22741 ccttacctgg cttagtttta ggtatatcat atataacttt tttcaattca gcaagtaatc
    22801 cattaaattt tttatatgga agtacagcaa tattagttat agtaaatata gttcattttt
    22861 attcagtttg ttttataact tcaaattcat ctttaaaaat gttggataga gagtatgaat
    22921 tagttgcaaa atccataagt attccattct ataaagtatt ttttaatata acagttccaa
    22981 tgtctataac atcaatactt gaaatagtag tatattattt tgtaaattca atggttactg
    23041 tttcagcatt aatattttta tatacacctc aaactcagac tgcatcaata tcaatactaa
    23101 agttagatga gatagggtat ataggaccat cagctgctat ggcagtatta gtgcttttaa
    23161 caaatataat agtaagactt ttgtacgaat ttgtaacaaa gaaattaaaa aataacacac
    23221 aaaaatggca gcaaaaagat gttgcatagg ggaggtaaaa atgaaattta agaagctagt
    23281 ttctttagga gtattatcaa cacttttatt aagtgtaata acaggatgtg gtactgattc
    23341 atcaggttca gattcaaagt ctgatagtaa gacaaaaggg gatttaacag tttacacagc
    23401 aattgaagaa gatagtatag agccatattt agctacattt aaagagaaat atccagatat
    23461 taaattaaat attgttagag catcaacagg agatataaca gcaagattat tagctgaaaa
    23521 ggataatcct caagcagatg ttgtatgggg agttgcagcc acaagcttat tggtcgcaga
    23581 tgaccagggc atgctagaac catatgctcc aaaaggttct gaagaaatag agtctgcatt
    23641 taaagatgat aaagaagttc cttcttgggt tgggatagat gcttggatga caggtataac
    23701 agtaaacact aaagaattaa gtgataagaa cataccagtt cctagttctt acgaagattt
    23761 aataaagcca gaatataaag gtcttatatc tatgcctaat ccatcttctt ctggtacagg
    23821 gtacttaaca gtatcagccc ttatacaaat tatgggggaa gaaaaagcat ggcagtatat
    23881 ggataagttg catgagaata ttggtgtata cactcaatct ggttcagctc cagctacatc
    23941 agcagcttca ggagaatatc ctattggtat atcttttgga tatagaggga taaaattaaa
    24001 agaggaaggt tatccagtag aagtagtatt tccaaaagaa ggttctggat gggatataga
    24061 agcaaatgct cttgtgaaaa aagataatat aaaagaagca tcaaaagtat ttttagattg
    24121 ggctataagt aaagatgcaa tgaacgaata ctctaagaac tatgcagtta ctactatttc
    24181 tacaggaaat ccaataccag aaggattccc taaaaagcca ttagagcaaa tgatagataa
    24241 tgatttaaaa tcagcagcaa aaaatagaga agatatacta aataagtgga tatcaaaata
    24301 tgatggaaag acagaaaaag agagttaagt aaaactatac aaatagagta aaaagaaaga
    24361 atttttttaa gtagatttta ttataataat ataagttaag aataatatag gtcaagaaaa
    24421 atgaatattc tataaaaatg tatagagtaa gtataccatt cagtttgaat ggtatatttt
    24481 ttatttttgg agattaattt agaaatagat atactacagt ttaaaatagt atattttaat
    24541 ttcattatta aagtatagat gttatataaa gtaaataaaa tattaaataa ttataaacta
    24601 aagtaaataa attattgagc gattattaaa aagatatata taaaatttaa tttgagcagt
    24661 ttgttatata ttataaaaaa agagaaaaaa taaaaggtaa attgtttctg gataacttaa
    24721 aattggaagt aagaatattt aactagagaa gaattattta agttcaggtt agctctagga
    24781 gtagctgatt ttataggaac aatagatttt atggatgatg atataaacat gatagcaatt
    24841 agaccagaag atataaaggt agaatttaat agagatttca aagatgttga tataaaagta
    24901 cgagagattt tggatattga atttagaaga ttcaactata tagttacagt ttaatatcgt
    24961 tctaagcaaa taaagttgaa tgtagtttca aatgtagtgg aacaaatgga actatgtgta
    25021 ggttataaaa taaacttcaa gatacctaaa gaaagaatca tataatataa gtaatccatt
    25081 aattttttta tagacctcaa actcagaccg catcgatata aaaactaaag ctagatgata
    25141 tagtgttgta tataggacca tcagctgtta tggcagtatt agtgctttta acaaatataa
    25201 tagtaaaact tttgtatgaa ttgataataa aaaaattaaa aaccaagaca taaaaatggc
    25261 aacaaaaaga agttgaataa gggaggtaaa aatgaaattt aagaagttag tctctttggg
    25321 aatattatca acacttttat tgagtgtaat aactggatgt agtaatgttt catcaggttc
    25381 aaacttaaag tctaataata agacaaaagg agagttaaca gtttatacag caattgagga
    25441 agatagtata gatacatact taactacatt taaagagaaa tatccagata ttaaattgaa
    25501 tgtacttaga ttatcagtag gaggtataac agcaagatta ttagcagaaa aagataatcc
    25561 taaagcagat gtgttatggg gggttgcagc tacaagtttg ataattttag atgacaaaga
    25621 aatgctagag ccatacgctc cgaaaggctt tgataaggta aatcctgcat ttaaagatga
    25681 taagaaagtt ccttcttggg ttggaataga tgcttggatg actggtataa cagtaaatac
    25741 taaagaatta aaagctaaaa atatatcagc tcctagttct tatgaagatt taataaagcc
    25801 agaatataaa gatcttatat ctatgcctag tccagcttct tcaggaacag gatatttaac
    25861 agtatcggaa ctcatacaaa ttatgggtga agaaaaagca tggcagtaca tggataaatt
    25921 acataaaaat attggtgtat acactcagtc tggttcagct ccagctatat tagcagcttc
    25981 aggagaatat cctattggta tatcttttgg aaatagaggt ataaagttaa aaggtgaagg
    26041 ttatccagta gaagtggtat ttccaaaaga aggttctgga tgggagatag aatcaaatgc
    26101 acttgtgaaa aaagataata taaaagaagc atcaaaagta tttttagatt gggctataag
    26161 taaagatgca atgaatgagt attctaagaa ttttgcagtt actacaattg acacgggaaa
    26221 tccagtgcca gaaggatttc caaagaatcc cttagaacag atgatagata atgatttaaa
    26281 atcagcagca agaaatagag aagctatact aaataaatgg atagaaaaat atgatggaaa
    26341 gacagaaaaa gagagctaag ctttacaata aaatttagta taaaaagcgc ctagaatata
    26401 aattttatat ctaggctctt ttgatatatt tatttaaaat gcatatttct atataaaaat
    26461 aaatagttta gtaccttgat taaattaaat aaaaacctta aaataaagag atgtaaagaa
    26521 aaactaaaaa cgaataaaag gtgaatttat atgataaaag aaataatagt agtagagggt
    26581 agagatgacg tcacagcagt taagagagca atagatgcag aacttataac tacaggtgga
    26641 tttggatttc caaaaggtgt aatggagcgt ataaaagctg ctaatgaaag acgtggtgtt
    26701 ataatattta cagacccaga ttttgcaggt gaaaaaataa gaaaaaaaat agcatcagaa
    26761 gttccaggat gtaaacatgc atttctacca agagaggaag ctaaaaagga tggagatata
    26821 ggtattgaga atgctactcc taaaagtata atagcagctt tgaataaagt tagaactgaa
    26881 aatacagaaa aaagagatga atttaagcaa gttgacttaa ttagaaatgg tcttataggt
    26941 aatgaagaag catcacttag aagagatgca cttggaaaaa tacttggaat tggatatgga
    27001 aatgcaaaac aatttttaaa tagattgaat aattatggag ttgaaagaga agaatttata
    27061 gatgcattaa aacaaatcta aacgtaatgt ttaatgtatg aaaaatatgt atataaaata
    27121 aattgtggaa ttacggttaa tttaagataa attatttata atatatacct tattttaaat
    27181 caatgtaaat acatataata agtataatta ataaaattaa atatcaaaat aagttaaaaa
    27241 ggagtaaata atggatagac tatcttcaca taatgcaaca aaggaagtag tacaaaaata
    27301 taattttaaa ttttcaaagt ctttaggtca aaatttcttg atagatagta atataattga
    27361 taaaatttta tcgggagcta gaatcacaag aggagataat atcatagaag taggacctgg
    27421 tataggaact cttactcgtg agatgggtaa aatagcagaa aaagtagtgg ctatagaaat
    27481 cgatagaaat ttaattccta tattgaaaga taccttgtca gatttagata atacagaggt
    27541 tgtaaatcaa gatatactaa aagtagacat acaggaatta gtaaaagata aattaaatgg
    27601 tggaccagtt aagcttgtag caaatcttcc atattatata actactccaa tagttatgaa
    27661 atttttagag gaagatatac ctgtaacaga tatagtagtc atggttcaaa aagaggttgc
    27721 agatagaatg aatgctattc caggtactaa agattatggg gcattatcta tagctgttca
    27781 atactattgc gagacagaga ttgtggcaaa agcgccaaga catatgttta taccacaacc
    27841 aaatgtagat tccacagtta taggtttaca tgtaagagat aaaagaaaat atgatgttca
    27901 taatgaagaa atatttttta aaacagtaaa agcatccttt ggacaaagaa gaaaaactct
    27961 tcttaattcg ttgggaggtc ttggttttct taataaagat gaaataagag aaatattaaa
    28021 agaagctaat atagacgaaa aaagaagggg tgaaactctt agtatagaag agttttcagt
    28081 tctttcaaat ataataaata caaaagtatc ttctaaatag aaggtacttt tttttatttt
    28141 gttaacatat attgtttaga gaaactgtgt taagggggga ttgcagtggg ttctaaaaga
    28201 aagtttaaaa gagactatat aatactagaa gctaaagaca taaactttag atacaaagaa
    28261 cgagtactgc caaaagcttt tgcaaaagtt gaagtaaatg atgaaaaagc aattattgca
    28321 ttatatgtag aaaatctaaa atatgttaaa gatgggtata aagcagtagc aataaaagaa
    28381 gaccatggat taatagactt aggaaatata attttaaatg aacaaggaag aggtgaattt
    28441 gttttagatt tagaagatta tgatgatgag ataaaaggta ttgcattatt gtatgaaaga
    28501 aatatacctt taattggatt taagggaaat aagattgaaa attatgagga catattattt
    28561 caagaggtag aggaagaaga atatgaagag ttggaagaag aagacgaaga gatagaggat
    28621 aatgaggaaa gtgatagaga cgaagatagt gaagaagaag aatatattat agaagaatat
    28681 gatgaagatg agtatgaaga ctattgggaa gatgatgaag atattgaaga aggagagtta
    28741 aaggcaagaa cggaagtaga agattctggt gatgaggaaa tagaagagtt caataattat
    28801 aaggaaatag aaaattataa tagggttaaa gtacaggaag aatatataga catagaatat
    28861 gatgaggaag aagaggatga agaagaagtt tttgaagtaa atagagaaga agacaggttt
    28921 gtttcctcaa aacctactaa atcaaagaaa gttcaaaaag atcagaataa tattgaaaaa
    28981 ataaaaagag ctaatggagt aagtcaagga gagagtggaa ataaacaaac aagtacatta
    29041 cttatgccaa gacaaataaa aaaaggtttg aaattattta aagaagtaaa accttttgta
    29101 acagattata tagataagac aagatggtgg aaaatagaga taaatcctac aactttgtgt
    29161 ggatatacaa tgccttattt aggatattta aacgtgctga attacaccat gtatagtgat
    29221 gcagttttac attcatataa atacagacac tatttatttg gagttcagta tgatgaatat
    29281 aataagagaa aacattatat ttatgctatc ccaggaaata gaaatgaaca gccagacaat
    29341 ggcagcacag gatttttaag atatcaagct tgtgataata gaacaaatag tttaggatat
    29401 tggctatgtt ttatagattc tagacaaaga aatatagtta gataaaaata ataaaaatga
    29461 aaaaatttag actcaattct tattttactg aaaaaattaa tgaaatgtag tacaaaactt
    29521 taaaaactat tgataatatt taaatattac actacaatat atcttgaaat acctattata
    29581 ttatggagga aaattatgat aaacgagcaa agaattttaa atgagtttct tgaattagta
    29641 cagatagata gtttatcttt aaaagagggg aaagttgcta aagtattagt taaaaaatta
    29701 gaagaaatag gttgttcagt agtaatagac aatgctggtg aaaaagcaaa tggagaaact
    29761 ggtaatataa tagctacatt aaagggaaat aaagaaggaa agaaaatatt atttagttca
    29821 catatggata cagtaactcc aggtatagga gtaaaaccta tagtggatga agcaaatgga
    29881 ataataaaaa gtgatggtac tacaatatta ggttctgatg ataaagcagg tatagcagct
    29941 atattagaag gcttaagata tataaatgaa aataacatag aacatactga tatacaagtt
    30001 gtattctcta tatgtgagga atgtggatta gttggagcta aaaatttaga ctatggaaaa
    30061 atagattctg aatatgcgtt tatattagat agtggtggtt ctccaggtga aataatagta
    30121 aaagctcctg cacaagatgt aataaatgtt aagatattag gaaagactgc tcatgcaggt
    30181 cttgaacctg aagctggaat aagtgctata atggtagctg ccagagcaat agaaaatatg
    30241 aatttactta gaatagacga agaaacaact gctaacatag gaattataaa cggtggaaca
    30301 gctacaaata tagtaacagg agaagttaat atagttgcag aatccagaag tttaaaagaa
    30361 aataaattag atgttcaaac taaacacatg gtagagactt ttgaaaaagc tgcaaaagat
    30421 tttggagctc aaattgagat agatgtcaat agagcatata caccaataga tgttagtgaa
    30481 gattctgaaa taataaaact tgcaaagaag gctttttcaa acttaggtat agaaggtcat
    30541 actgaatcta caggaggagg tagtgataca aatatattaa gtaagaatgg tatcgaagct
    30601 ataactttag gaatcggtat gaaaaatgct catacactaa gtgaacatat agctataaaa
    30661 gacttatacg attctgctaa aatggtagtg gagataataa aggaagcata aatttaaata
    30721 atagtgtata atatatatat cgcctagctt aagctaggtg atttttcatt ttatagaaga
    30781 ttgataatct ctattgaaag taaagagtat acatttgcat ataagagaga gtttaattta
    30841 tgttcagatg taggttctta ataatattta gattgtttca taagggagga ataaatatgg
    30901 aaacaaggta tgaagaagca aataaaataa caatacaatc aatactttgg aatgtagtat
    30961 taacaataat taaggttata gctggtgtta ttggtaattc tagcgctatg attgcggatg
    31021 gattacattc agcatcagat attataagtt ctataggagt actaataggc aattatgtat
    31081 cttctagacc tggagataga gagcataatt atggtcatga gaaagcagag acattagtat
    31141 catttgtgtt atcaatattg cttattttcg tttctataac aataggtata gaggcaatta
    31201 aatctttatt taacttagat gcattaagtg ttccatcaat attaccatta gtagtatcag
    31261 ttatttcaat cctgataaaa gagtatcaat atagaataac aataaaagtt gctaaaaaga
    31321 taaattcacc agccctaaaa gctgatgctt ggcatcatag gtcagatgct ttatcttcag
    31381 tagctgcttt tataggtata ggaggttcta ttttaggatt taagccatta gacccaattg
    31441 catcagttgt agtggctata tttgtagcta aagtaggaat tagtatactt ataagttctg
    31501 ttaatgaatt gatggatgtt tcagttgatg aagaagagat aaaagaatta aaatttattg
    31561 tagcagatac agaaggtgtt aaaaatcttg gtgatataaa gactagaaaa catggagcta
    31621 tggcatatgt agatttgact atatgtgtgg atgaaaattt gacagttaag caaggtcatg
    31681 atattgctac taagcttgaa aaacatataa taaagcatat ggaatttgta aaaggcataa
    31741 cagttcacgt tgaaccctgt actaattgcc aaggaaataa gtgtaataat taattaaaac
    31801 ttaaaaaaaa gtgtaaaaag ttatataatt gttttatgat tataaactct aggggtggtt
    31861 aaatgagcaa gaaaagaaaa ctaaagaaaa aagctgcaat attaatagga gtagttgttt
    31921 tctttataat atactttata tcctttagaa taggaataaa tatggaaaag gataaaagtg
    31981 aagtgccaaa gaaggtagaa aaagaagaag aagataatag gtctttaagg actcaaataa
    32041 aagaaaagaa gaaggtttat atatcagaca aaaatataga aaacataaaa attgaagaag
    32101 atatgtggga tgaaataaag ttatttttct cagattttaa gaaagtaagg aatactactt
    32161 cttcttacga agcagtttat gaaggttatt ctgatgatgg agttaaattt tctactgacc
    32221 ttaacttttt tagagtatat actgtaaata aagaagaata ttataaagta ccagttagtt
    32281 ctaaggatgc ttttaagaaa cttttagatg agagtatata tacttcgttt gaccttttaa
    32341 gtcattataa agattggaaa gaggttacta taactcatgg aaaagaaatt aaaaaagttc
    32401 acagatggaa atttgatgat ttagcacata agatgatttc aaaaagggtt gtaggaaaag
    32461 ttcaacctga gaaaagtaag gaaagaagtg actataattt tactataaat ataaaaggtg
    32521 ataattttga tgtaagagtt gatacaatgg gaaaagatta tgtaaaagtt acttctaaga
    32581 aaaatgtatc ttactatgag gttcatacaa gtttatttga ttaccttaaa aatgagatat
    32641 ttgaaattgg aaagaaataa gactttaaga aggctatcaa attagatatt tgatagccta
    32701 aagtatttta tatattattt ttcaaccaat aagtctgcaa ccttataaat tggaccagca
    32761 ccagcagtta ttactaaatc attgtcctta acattttcac gtaagtattt tactatatct
    32821 tcaaattctt ttatatagat ggcatctaca ttgttctgat ataatttctc aaccaagtcc
    32881 ttagaatgta tatctcctgg gtctttttcc ctagcagcat atatatctgt tatgataact
    32941 ttatcagcag catagaatgc ctctgaaaat tcacctaaaa gagattttgt tctagtataa
    33001 gtatgtggct ggaagataca ccataaagtg gattttttta attttttagc agcagctaaa
    33061 gtagctttta actcagttgg atgatgtgca taatcatcta ctactaaagc attcttatag
    33121 taccctttag tttcaaatct tcttccgaca cctttataaa tttttatatt ttttcttata
    33181 gtctctaagt caataccaga aacaagagct gccattatag cagaagaagc attgtatatg
    33241 ttatgaagac catatacaga aagttcaaat tctcctaaat ctcttccttc atattctatt
    33301 ctaaatattc catgaccact attgtcaaag tgaatatctt ttattacagc atcattgtca
    33361 gaatctctac catattttat aatagtagct ttaacatcat acaatatgtc atcaatattt
    33421 tcatcatcgc catttattat gaaatagcct tctgggggta ataattttcc aaatttgtta
    33481 aaagaagcct tgatttcatc tattccagag aaataatcaa gatggtcttc ttcaacattt
    33541 aaaactatag atatttttgg gttaaaatta aggaaactat ctacatattc gcatgcttca
    33601 gttataaagt ggttggaatt acctatctta acattaccac ctatcatact taagttacca
    33661 ccaactagta tagttgggtc taagtctgca tattcaaaga ttgtagataa catagatgtt
    33721 gtagaagttt ttccatgtgt tccagaaact gctatagaat ttttatattc cctcatgatt
    33781 tggcctaaaa aagtcgctct gttcattacc aatttatttt tttctttagc agccacaagt
    33841 tcttcattgt ctggatggac tgctgctgta taaacaacca tatttacatc atctgatata
    33901 ttatcttttt tctgaccaat ataaatagtt gccccttggt ccctaagttt gtctaatagg
    33961 tatgattcgt ttgaatccga acctgaaact tgataacctt tattgataca tatttcagct
    34021 aatgcactca tgctgatacc gccaattcct ataaagtgta tattcataat aaaaccacct
    34081 ttctttttaa ttaagtccta caatatgaac tatttctgtg gtataataat ataatgttca
    34141 atattttata attaatatgc atataatatt atatgtattt tatttttgaa tataataaaa
    34201 cataagtaat attataccac aataagaatt gttatgcatt agttagttta acgttatata
    34261 aaggtacttg taggaggaaa taataatgaa atttaaaaga acagagagaa ttggagcaat
    34321 agttaaaata ctgtctgata atccaaataa aatatatact ttaagttatt ttacaaatca
    34381 atttaatgca gcaaaatcaa caataagtga agatttatta gttgtgaaaa atgtatttga
    34441 gaagctacat ttaggtaaag ttataactat ctcaggagca gcaggaggag taaaatatat
    34501 acctaaaact tctatagcag aaaatgcaga gttcttaatg gaattatgtg agagaatatg
    34561 tgacaagtct agaatactat ctggtggttt tttatacttg attgacctaa tttacgaccc
    34621 tacaatagct gctaagatag gaaagatatt cgcatcaaat attgagtatg tagatgcaga
    34681 ttatgttgta acaatggaaa caaaaggtat acctatggca cttatgactg caaaagctat
    34741 gaatttacct ctagttataa taagaaaaga tataaaggta tcagaaggtc ctacacttag
    34801 catgacatat gtgagtggaa acagctctaa agttgaaagt atgagtttgc caagaaaagc
    34861 tcttaaacca gatagtaaag ttataattat agatgatttc atgaggggtg gaggtactat
    34921 aaaaggaatg gtagacctta tgaatgaatt tggtgcagag gttataggta ctggagtatt
    34981 catatctaca acgaatcctt cagaaaaaat ggtaaaagat tatatttcat tgattcaatt
    35041 ggatgttaat ggagataaaa tagtagtaga accaaactta aagactttta aagatgaata
    35101 tagaaatgaa gatttagacg aagaagaaga ttcagaattt gaatttgaga tagatgaaga
    35161 ttaataaaaa aaatatttag aaaaatatgt aaaaataaaa agaggatatc cctagttgtt
    35221 catagaatta tttaaaaaac agtttatatt aatttattcc agcgataata attttaatat
    35281 aaattaattt ctgtcaaaat caaaggggga tattttggta tgaagataac tgacgtaaga
    35341 gtaagaaaat taacagaaga aggtaagatg aaatgtatag tttcaataac tttcgataat
    35401 ttgtttgtag tgcatgatat aaaagttata gaaggccata atgggctatt tatagcaatg
    35461 cctagcagaa aagtaggcga aggaaatttc agagatatag ctcatccaat aaatgcagaa
    35521 atgagacaag ttttagaaga tgcagtttta caagcatatc atgaagcatt agttcaatgg
    35581 gaagtagctg ctgaataata ataaatatat aaaatggaga gagcccgaac atttaggctc
    35641 tttttaaatg tagaatttct attaaaatat gtacttttta gtaaaaaagt gctatattat
    35701 tagtgataat gtatatgttg tatacaaatt gttagataaa tgtattataa tgtatattga
    35761 ttaagagaat aatacgaata aaattaaatt agattgaatg gagtgtatca atgaacttta
    35821 aagctataat ccttgctgct ggcaaaggaa caagaatgaa gtctaaatac ccaaaagtta
    35881 tacataaagt atgtggaaaa gaaatggtta accatattat agatgtttca aaaaaatcag
    35941 gggtaaaaga tactgttgtg attttagggc atgaagctga tgtagttaaa gaaaagcttg
    36001 cagaagaaat tataatagcc atgcaaacag aacaacttgg gacaggacat gctgtaaaga
    36061 tggctaaaga atatattaat gatgaagata caatagttgt actttgtgga gatactccac
    36121 ttataaaaga agagacacta aagagattat ttgaatatca tatagaaaat aaatatcatg
    36181 ccacagttct tacaacaaga gttggaaatc caacaggtta tggtagaata ataagagata
    36241 agaagggtga ccttcttaaa atagtggaac aaaaagatgc aaattcagaa gaaaagatga
    36301 taagtgagat aaactctgga atttattgct ttaatggaaa gagtcttaga gaagcactag
    36361 atttgctaaa taataacaat tcacaaggtg aatattattt aactgatact gctaaaataa
    36421 tgagagataa aggattaaaa gttggtgcat ttgcaggttc aactattgaa gaacttatgg
    36481 gcgttaattc aagagtagaa ttatcaaagg cagaagaaat tatgagacga agaataaatg
    36541 aatctcatat ggtaaatgga gtaactataa tagacactaa ctctacctat atagaatctg
    36601 atgttatgat aggcaatgat actataatat atccaggtgt tatgttacaa ggaaaaacaa
    36661 ggataggttc agattgtata attggaatga attcatctat aacaaattca gaaataggtg
    36721 atggtacaga aataaaaaat tcaactataa ttgatagtaa ggttggagaa aattctactg
    36781 ttgggccata ttcatactta agaccaaaga gtgacttagg aaataatgta aaaataggtg
    36841 attttgtaga agtaaaaaat gctattatag aagatggctc aaaagcatct cacctttctt
    36901 atataggaga tgcacatgta ggtaaaaatg taaatattgg atgtggagta gtatttgtaa
    36961 actatgatgg taaaaataaa tttaaatcag tagtaaaaga caatgcgttt ataggttcaa
    37021 attctaattt agttgcacca gtagttgtag aagaaaaagg atatatagca acaggttcaa
    37081 caataacaca tgatgtccca gatggtgctt tggcaatagc aagagaaaga caagttatca
    37141 aagaaggatg ggtagaaaaa aagaatcaaa aagacgacca aagtaagtaa ttatgtagtt
    37201 tattattttg gctaaaaaat ttagctcgaa attattataa attatattca ttagtatttt
    37261 aaaattttca ggagggttac ataaatgaat actagcggaa gcgagattaa aattattgca
    37321 ggtaattcat cgaaagagtt agcacaaaaa atagctgact atataggtgt atcagtacta
    37381 gattgtgaag taggtacatt tagtgacggt gaaatatgtg taaacatgaa tgagacagta
    37441 agaggttgtg atgtgtttgt agtgcaatct actaacagcc cagtaaatga taacttaatg
    37501 gagttattaa tcttaattga tgcgttaaag agagcatcag caggtagaat aacagcagtt
    37561 attccttact atggatatgc aagacaagac agaaaggcta aggcaagaga tccaatcact
    37621 gctaaattag ttgcaaattt aataactgct gctggagcag atagagtatt aacaatggat
    37681 ttacatgcag ctcaaataca aggatatttt gatataccat tagaccactt actaggtgga
    37741 acaatattag caaattattt taatgaaaag aaaatagaag atttagtagt agtatctcct
    37801 gacttaggaa gtgttactag atcaagaaaa tttgctaata ctttaaatgg agaagttcca
    37861 atagctataa tagataaaag aagaccgaaa gctaatgtat gcgaagttat gaacttaata
    37921 ggtgatgtta aaggtaaaaa tgttatacta ttagacgata tgatagatac agcaggaaca
    37981 atagttaatg ctgcaaatgc acttaaagag tttggagcaa aagatgttta tgcttgttgt
    38041 actcatggtg tgttatcagg tccagctatt gaaagaattg ctaattcaga aataagtgag
    38101 ttaatagttc ttgatactat acaacttcct gaagagaaaa gaatagataa gataaagata
    38161 aaaacagtag ctcctttatt tggagatgct ataagaatga tattctctaa tgaatcagta
    38221 agtaaattat tctaatttat tgtatttaga agagttgttt aaaaggctgt aaaccttttg
    38281 agcaactctt ttttgatttt atacttatga aatgctattt ttctcttgtt agaaaggtat
    38341 atattattgt agaaagaaat tatagtttaa aattatgtat atttaagcaa aataaactta
    38401 ataaagggca tattattcat aatattgtga atataaaaaa tattacaaaa aagtattgaa
    38461 aaaattcaga ttatgtagta ttatgtaaat ataaataaag aaagaggtgt ttccaatggg
    38521 aaggttagaa gatgaacccc taataattaa atgattcagt cacaatctaa agtgaatata
    38581 aaaatctatt gaaagtttat ttataagaat tgaaaatagt atctattcta tctttagtgt
    38641 ttgtgagagg gttctggatt atataagatt actgtaaaga agtaattttg aacaataagc
    38701 atatctgtaa atgaagagtt tcgtttatat aatgattgtg gctgaatcat aactataata
    38761 gatagaatgt ttataataga tgattttata aaatactata ttgtaatagc ttttagcttt
    38821 caaataaata ttagcaaagg atggaaatga caatgataaa actaaatgat aatttataaa
    38881 tatctcctta cgatatataa taattgtagg gagatgtttc tttttttgta tagtataatt
    38941 ttttctagaa attctgtttc aatatgtaaa aagttggtat atataaatag tataaactgt
    39001 gttgctaaaa tatggtagat attatataat ataagtggat atgtatatac attatgagtt
    39061 atataatttt gaatttaata aaatagaaac gttgatttat gttctgtaat gtgggcacct
    39121 tggagcatat tgagttagtg gtgcaaccgg ctatgaaatt gtatttattt atagatacta
    39181 ttattttcat agcttttttt atttaaaaaa tggttatatg ttagaaataa atttggttag
    39241 tacgtttaaa taattttact tagattttta accagatata ttataagtaa gtattaatta
    39301 aaaaatttaa gggggaataa aaatgaagtt aaaaaagaat aaaaaaggtt tcactttagt
    39361 ggaattattg gtagtaattg caattatagg tatattagca gtagtggcag ttccagcttt
    39421 atttagtaat ataaacaagg ctaaggtagc aagtgttgag tctgattata gttcagttaa
    39481 gagtgcagca ttatcttatt attcagatac taataaaata ccagttacac cagatggtca
    39541 aactggttta aatgttttag agacttatat ggaatctctt cctgataaag ctgatatagg
    39601 tggaaaatat aaattgatta aagttggtaa taaattagta ttacagatag gtaaagatgg
    39661 tgaaggagtt accttaacag aagcgcaatc agcaaaatta ttgagtgata taggtaaaga
    39721 taaaatatat acaggtgtta caggagataa ttttggagac caattaaaag atactacaaa
    39781 aatagataat aaagctctat atatagtact tatagataat actgtgatgg actcaacaaa
    39841 atagttaaaa caatatcttt ataaaaatat tgtaaattta atgaaaaata taatataaaa
    39901 gacaggaaga aaatcttcct gtttttttat actattttct ttaatgttca attatgaatg
    39961 atgatataat tgagatagta aaggagtgaa acctgtggct aaaaaagtta gaataggaga
    40021 caaactggtc gaaaaaggat atataacaga agaccagctt aaatgggcac tatcagaaca
    40081 aaaaaacagt ggaaaaagac taggagaatt tctagtacaa gaagggctta tagatagtaa
    40141 cttactaata agtgtattaa aagaactctt ggatatagaa agtatatttt tagaagggac
    40201 agaaatagac actttagcta caaagatggt tccagaaaat atatgcaaaa gatatactgt
    40261 atttccattt aaaatcgatg gaaataaaat atgtctagcc atgtcagacc cacaagatag
    40321 agaagcagtt caagatgtaa ggcgtatgtc tggtaaagac gtagagatat ttatatcaag
    40381 tacagaagat ataaacaaag caataggtca tgcttatgca cattcagaaa taaataaggc
    40441 aatgactgag tacaacaaaa atagaactgg tggagtaaga gaaacagtaa tacttgaaga
    40501 agatgtaaat gctgctccaa tagtacgatt agtaaataac atactagaaa atgctgttag
    40561 aatggaagca agtgatatac atatagaaca aagtgaaaat tacatgcgtg ttaggtttag
    40621 gatagatgga atgttaagag aatatatgag gatgaactca gcaccatata aggcagtaat
    40681 cagccgtatc aagataatgt cagatataaa tatatctgaa aagagaatac cacaggatgg
    40741 tagaatctat ttaaaagtag ataataaacc catagatttt agggtttcta caatgccaac
    40801 taacagggat gaaaagatag ctatgagggt tcttgataag agtaatttta tggttagtaa
    40861 agaagtacta ggaatagacg aacatggctc taagatatat gatgaattga taaacactcc
    40921 ttatggtctt atattggttg ttggccctac tggaagtgga aaaaccacta cattgtattc
    40981 aatgttaaat caactaaaca cagaaaatag aaacctatta acaatagaag accctataga
    41041 gtatgaatta cctggtgtaa atcaatctca aataaatgaa aaggcagggc ttactttcgc
    41101 cagcggactt agagctttta tgcgtcaaga cccagatata ataatggttg gagagataag
    41161 agatactgag acagcagaaa tagcaattag agcttctctt acaggacatt tagttttaag
    41221 tacattacat gcaaatacag cagttggagc aatttcacgt cttttagata tggatgtgga
    41281 aagtttttta ataacttcat ctgttttagg tgtaatatct caaagactta cacgaaaaat
    41341 atgtgagcac tgtaaggttt catatgaagc agatattgga gaaaaaaagg ctcttggtat
    41401 tgatgtaaat gaatcaataa ctatttatag aggaaaaggt tgtgaaaggt gtaataatac
    41461 tggatataaa ggacgtctag gtatatttga aatgcttgaa attactccag aaataaaaga
    41521 gttaatagat tcatctgcaa atcaaagaga aattttaaag atggctagaa aacaaggtat
    41581 ggttagctta aaagaggata tagttaaaaa agttttaaat ggaaagacaa cagtagaaga
    41641 aatgattaga ataattttga tgactgatta aaggatgata ttatgaaaag ttttaaatac
    41701 acagtaataa aagaggacgg aaaaaagcaa actgatgtga ttgaagccaa tgattttaat
    41761 gaagctagaa atcttcttag aaagagaaat cttagagtta ttgaaatcaa agaaagcaaa
    41821 aataaaaata taagattatc tagtagaaag agaaaaaaag acttgggagc tgaccagata
    41881 agccactttt gcagacagtt tgctattata gtatcttctg gtataaatag tatttctgga
    41941 ttagaaacat tagctagaag gtcaaccaac attacattaa gagaagaaat taatcgtata
    42001 gtggcagaaa taaaagtagg ttctactatt gcagattcaa tgctttcatc aaaatcaaag
    42061 tttccaaagt tactcggtgc tatggtagct acaggtgaag ctacaggtaa attagatgaa
    42121 gtattaaaaa gtatggcttc attttatgca agtgaacaca gagttaaaca aaagcttaga
    42181 aatgctgcaa catatccatt aatagttttg atttcttcat ttataatgat ttttatattt
    42241 acaacattta tggtacctaa gatgattaat tcaattacaa cagtaggagc aactcttcca
    42301 cttataacaa gaattgttat ggggtttggt atgtttatga agaagttttg gataatagta
    42361 cttttagtta ttatattatt tatctatcag tttaaaaaat atctaaaaac gccagttgga
    42421 agggctcata aagatagagt tataaacaag atacctgttt taggaaaagg aataaattgt
    42481 atggtagcta cacgattttc aagagcattg tatctatttg tatcaacagg atacccatta
    42541 gttcaagggc ttgattatat tatagatagt gtaaataaca ccatggcaga aaagatttta
    42601 gtatcagcta aagatggaat aacaagagga gaaggtttag cagaaaattt agaaagatat
    42661 acgtattttg actctgtatt ggtacagatg atagctatag gggagcagac aggggaatta
    42721 gagaatataa gtagacagat ggccgaattt tatgagtatg aatccgagat ttatttaaat
    42781 aggatggcct caatgataga gcctgtttta ataattgcag ttggtattat agtttcgata
    42841 ctggttgtat caatatttat gccaatgctt agtatatatg atgccatgta ggagggaaat
    42901 gacaaatgaa caaggtttat gtatcatatt atggcgattc tatttccata gttgagggca
    42961 gatataaaca cgataaggat aagttttatg taaaaaattt taatgtgttt tcaatagagg
    43021 atattgcaca agatttttct aaggaaaagt atgctctatt gagatacgca ttagaaaatg
    43081 ttaagttaaa atcaagacat gtagtttttt gtttaaatac aagagatgta attttaaaac
    43141 cccaaaaact tcctaatatg gataaaaagg atttagacgg atttatgaag ctagagatgg
    43201 acgaaatgat ggctttggag tcagatgaat acgtattttc gtatgaagta tctagtgaaa
    43261 cacctgataa ttcagatggc gatgaatcaa gcttaaatct tatcattgga gctatacaaa
    43321 aggaagaggt aaatgcaatt gtagagataa tgcatgaatt tgatttaata ttagatagaa
    43381 tagatacatt atcaacagct tacttaagaa tgcttaaaaa tttagattac aatgatataa
    43441 tggtaaccaa tataagtgac aatagcacaa ttataaatat atataagaaa gatactttat
    43501 ttattagtga taatatacct ataaagataa ctgctaaaga tatggacatg caattattaa
    43561 atgtagtaga agaatcaaaa ggtcttatga attactattc gtcaagaaac tttggtaagg
    43621 ttacggatac tatattaata ttaggaaaaa ggtattccaa taaattaatt tatgaaactt
    43681 ttagctctgc attttcaagc tatgtttctc aaggtcttac tgagataatg gatatatctg
    43741 atatgataac tggagatata gatgaagatg atataaattc aattgtagag cttttaggaa
    43801 gtatgataga acctaaaggg aaaagagatt ttgaaaatat aaacttttta ccaatggata
    43861 tacttagaaa acaactaaaa gctaaacaga tgaaaaacat actgaaaatt gttccaatag
    43921 ttattttgat tcttgctata ccttatttat gtttaatttt ttcaaataat ttagcaaata
    43981 aagaacttga aaatgttaat ggtgaaataa gaaatattga atctgcatat tatcagattg
    44041 ggaatataga aaaaatgata cagagtaaaa gcgaagaaat aaaggtatat gatatgttaa
    44101 ttggaaaaaa ggtaaagtgg gaaaatttat tggatgatat agataaaaat actccaagta
    44161 aagttgaact aacaagttta tcaacgactt atcaaaatct tggaactaat aataaagctg
    44221 ataattcaaa aagtaataag actacagcag ataaatcaag taacaatgaa acaaaatcaa
    44281 atacgaaaag tgatagtaat ggagataaaa caaataatga tttaaatgaa gataagacta
    44341 caaatgtgtc agaagcatta actggaaata gtgagactaa tagtaataac acagataaag
    44401 atgataaaac tccattgtat gataagatac caaatgttat aaatatagaa ggaaatgcta
    44461 aagattcctc ttatgtaggt caatttttat ataaattaaa gggattgtac tatttcgagg
    44521 atgttaaatt acatagcata aaaagtaatg cagaagattc tacctataca tttagtatga
    44581 cattatacct gaaagaaggt gtattaacta atgaataaag atatatttaa aaaagatata
    44641 aaagatatat ttaaaatgga agttagtcta aaagggattc ttataaaggt tataatttta
    44701 ttagctattt tatcatatgg ttattttgga ctttaccctc aatatcagaa atatattgct
    44761 acaaaaaatt ctgtaaaaca agctactgaa aaattaaata tatataaaga gaaaactgca
    44821 cttatgccaa aatatgaaaa acaacttgaa gaagttgaaa gtgaattaaa agaaaaaagc
    44881 aaaaatcttt tatatgatat gcaagatggt ctttttttaa taggtttaga taaaaaaatg
    44941 aaggcttata atatagactt aactagttat gacgttggaa atgttagaga atacgaacat
    45001 ttttatggtg tatcaacaac aataagtgtt agaggtgatt atagaaatgt caaaaaatta
    45061 atggcttatt tagaagaaca aaaaaatgtt actcaaatac tagattatac aatgacttca
    45121 tatatagaac cagaaaaaga agaggaagaa acaacaaaca ataaggattt aattaaaaat
    45181 gtgaacataa ataaagatac aaaaatatac tgggtggaag gcgaaaataa gtggcattta
    45241 tataaggatt gtccattgat aaaagaggga gagattctaa aaaatgacaa acttttagat
    45301 aggtctacta gttatctatg taatacttgt gtacttagag ctgcaacaga aaaagaagca
    45361 aaaaaagaag tcgtagctcc aaaggcagaa ggtgtagtag atgctacatt taaatttata
    45421 atgtacacta aagagaatac tacaatgata cttgatacag ataatccatc ttcatggaga
    45481 ccgggaaaat ataatccatt taagtctagt gcgaaataaa gctaagtaag ctttaaagat
    45541 aggtgatgag tttgtacaaa aataatgaaa aaggtcttac cttattagaa gtaataatag
    45601 ctgtttttat gatgacaata gttttaagca tttcttataa agtgttcaat ggtataacat
    45661 cagcagtaaa aaggcaacag attattacag atgctcaagt aaatattaat ctaattaata
    45721 agtatctaaa tagagatttg gaaaactgta aagagctaac taaaactggt tcaggtaata
    45781 attatgagta caatatagag atgccagata atgttgtaaa atatgaagtt tctatagaaa
    45841 ctaaaaaaca tacagaggta tattctgtaa cgagaatcca aaaaaataca attgatacag
    45901 aaaatgaagt tagagaagag ataatctata atcaaccact agttcaaaac aataaagaaa
    45961 tgaaggaaac accatttaaa atagaaaagc aaactggtaa atctatttat actgtaagta
    46021 tatactataa tgaatcagtg caagaaaatc ataaaaatag caatttaaat aacaaaactt
    46081 atacatttga tgttatgtca agaatagggt aataagaatt tattaaaaat aagtaggttg
    46141 ataaaatatg agtaaaaaga atagtgaaag aggattttcc ttaattgaag tgttagtagc
    46201 tatggctatt atgggaattg tactatttgc attttttaat attatcaata ctaataacaa
    46261 agcaaacact aaaaatgaca cagatataac ttccttaaac tatgtccaaa gtgaaataga
    46321 aaatctaaga gaaaagataa aaagtggaga atttgatttt gatagtttag ataaactaga
    46381 agatggaact gtcgtatatg aaaaattaat agataaatca aaaaaagttg tatatgataa
    46441 ggttcttagt aagggtgacg tgagcttata tgatactcca tatgaaaaga ttacaacaat
    46501 aaaagatgaa gatggtaatt taatcggcaa agaaaatatt acaaataaga taaagactat
    46561 tgtagaagat aaaagtggtc agatatataa aatagctgta actggaaaaa gcatgaatga
    46621 ctattcaagt aaaaaagagg ttaaaattgt aactgaaata tttaaagata aataatttta
    46681 cttgggggtg agattttgag gaagtggaat aaatttaaaa gtgaaagagg ggcagctttg
    46741 gttttagttt tggttgtagt agcattgctt tctattgttg gattgatatt ttcaaatcag
    46801 atagccaata gaataaaatc tacaaagact actaatgagg gtatacaagc aaagtattta
    46861 gcagagacat gtgtagaaaa tagtattgat aaagcatatg aaaaattgta tgatgaactt
    46921 gagaaaatgg ataatgagtt taaaagtgaa aatcaagaaa aatccatatc taggtcaaaa
    46981 ttaagaaata tatcagatga agattttaat aatcaagatg aggaaaatat tgaagcagaa
    47041 agactaggat atatgaataa tataaatttc tatttaaata aagcttcttc agaattggaa
    47101 aaagctagta tggaattgaa aaagttatat gatttagata tgttggacta tagagacatt
    47161 gaatatgtag atgcaaatat tatttcacat agagattcta tcttagaaat ttgcaagaat
    47221 tatacttctg gagatattag taaaataaat gaacatattc tgaaagaaga tatagactca
    47281 actacattga ttgaagcaaa gttagtaaat aatgatattc ttttaaaaat gtttttagaa
    47341 gaaaataaaa ttgaaaatga acatttaaat tcagcctttt cacatactta taaggcgtta
    47401 gataacattt ctttggcaat gcaaaatatg attgagtata gacatacatt tcatatagat
    47461 gagccaaaag tagaagtatc taatgggatt ccaaattctc aagaatatta tgaactaata
    47521 caaaatccta taataaatag tatggagtat agctggaata gtaaatggga tacattagaa
    47581 aacctattgg aaattttacc aaatcaaact caaggtttta attctttaag agttcatttg
    47641 agaaataatg taagaaaatt tgagaagtta agcgataata tatctagtgg taaaaaaaat
    47701 acagcaaaaa atttcttaaa gtataaagag ctattgtatg aaatatcaga ccaatgtaat
    47761 caactaaaaa gtatgtctta tgagaaaata cctgttaaat atgataacat ggctttgata
    47821 acaacttttg actatataca aaatgagctt ttagcagaga taaaatgtag attaaaagaa
    47881 ttaaaacccc aagaagttga taaaacagaa ggtattagta taaaaatacc tttttataag
    47941 gctgactacg acatgacaaa agaaggatgg cctaaattaa aagaaaatgg ttcaggggcg
    48001 gagttaagct taatggtaac tggtgataaa gatggaataa aagaagtaga agttacagat
    48061 agtaaaaaaa atattattgg tttaggtgtt gaagaaaatt caaattcaaa gtataaggtt
    48121 gaggccattg taaactttaa tctaaatata gatacaaatg tagttggaaa ttataatata
    48181 aaagataaaa ttttgattaa tcatgatata agttcataca aaaaagtaaa ctaaatataa
    48241 ggagtaactt agtataaata aataataaaa taattttatt atttactact aaaaaaataa
    48301 gtaaactaat agaagatatg gagagtaaat attatgtata tttatgattt attagagcaa
    48361 ggtataagac taaacgcatc agatatacac ataacagttg gaacaaatcc tgtagctaga
    48421 gtaaaaggtg gatttgtaaa actaagtgaa caaatattga catcagaagt aacaatgcaa
    48481 atggcaaaag acatagcagg ggaatctatg tttaaagtaa tagaagaaca tggagaagct
    48541 gatttttcag cttctctaaa aacaggagaa agatttaggg taaatgcata taggcaaaaa
    48601 ggaaattacg caatagcaat aaggactata acagcagaaa ttccaacatt tgaaaaatta
    48661 ggtcttccag aaaatataaa atcttttact gaaaagcata aaggattagt cttagttaca
    48721 ggtccaacag gaagtggtaa gagtacaaca cttgcaagta tgataaacat aataaatgaa
    48781 aaacaacaaa aacatataat tacacttgaa gacccgatag aatatgtaca tcaccataaa
    48841 caaagtttag taaatcaaag agaagtagga actgatacag aaagttttca ttcagccctt
    48901 agagctattt tgcgtcagga cccagatgtg atactaatag gagagatgag agaccctgaa
    48961 actgtttcaa tagcattaac agcagcagaa acaggtcatt tagtattttc aacactacat
    49021 acagtagggg cagctaagac aattgataga atagtagaca tgtttcaacc atcccaacaa
    49081 caacaaataa aaacacagtt atctacagtt tgtgaaggtg tggtatcaca gcagttactt
    49141 cctacagcag atggaaaagg cagaatagca gcaattgaat tgatgtttgc tactccagca
    49201 ataaaaaacc tgataaggga aggcaaaaca tatcaaattc caaacatgat acaaactgga
    49261 gttaaatcag gtatgaaaac tatggaccaa gatttaatgg aactttataa aaatggaaag
    49321 attacaaaag atatggcact tagtaggtgt actgaccaag agtttatgac aagaatgata
    49381 ggtggagtaa actacaatgg atattataat cgttaatcta tatgtattta tagttggtat
    49441 agtgtttgga agtttcttta atgtctgtat ttttaggatt ccagaaggta tatctatttc
    49501 tagacctccc tcccattgta tgagttgtaa tactagacta aagccaatag acttaatacc
    49561 agtgctaagc tatttaatga gtggcagaaa gtgtagatat tgttatgaga aaatttctag
    49621 tagatatgct atagtggaat taattacagg aattttattt ttaacagtat ttatgttata
    49681 tggaatatct acatcaacta tttattattt ggttcttgtg tctttactga ttataattac
    49741 atttatagat attgaccact ttataatacc agataaaata ctgatttttg gagctatatt
    49801 ttctataatt tttaaccttt tatttaaaga aattccagtt aaggattcaa ttataggtgt
    49861 ttttatttgt ggaggaagtg tctggattat agttcttttg attgaatttg taataaaaaa
    49921 agagtgtatg ggtggaggag atatcaaact atttgcaatg ctaggtcttt acatgggtgt
    49981 taaaaatggt cttttgacag ctttactaag cgtttatgtg ggagcagtct atggaatctg
    50041 tgtaataatt acaagcagaa taaaaggaaa ggaatataat tctgttatac catatggacc
    50101 ttttatatct attggagcat taataacaat cttatgcgga aaacaattac ttgaatttta
    50161 tttttctatg attatataga tgatagtcaa gttaaataaa gttttaattt aaaaaaatga
    50221 attaaagtat ttaataagga caatattatt attaacccta ttactaaagt gctacaaact
    50281 atggagtata taataataat ttccttattt tttgcacatt tgataaataa atctctatgt
    50341 gttttttgtg atagagaaaa gaaaaattta tataatacgt tttttattta cataataact
    50401 gtagttttat ctgtattaat atatctaaaa tttgggatta gtgtagaatg tgtacaatat
    50461 atggttttaa ttccattttt aataattata tccattgtag attactacac aatatatgta
    50521 tatgatataa caatagttag tggtataata gttcaaggta taattttttt ggcctttttc
    50581 aatatagctc aatttgatta tataaatcat atatttggac tattgatagg ctttattata
    50641 ccttatatta ttgctaaact aacaaaagga ttaggctatg gagatgtagg tctctatagc
    50701 ttatgttgct ttgcattggg aaataattat gggttttatg tgatagtttt atcatttatt
    50761 ttagcgtttt tgttttttat tattttatac ataactaaaa tatttaaaga tgtagatata
    50821 agaaagcaaa ttccttttac accttttatt tccttgtcaa caattttaat aatatttaca
    50881 gagtataata tatttaattt ttattataat ttgttataca aatttatata acaggaggta
    50941 agaaatgtac gtagtagtag ggttaggtaa tccaggaaag aagtatgaga agactagaca
    51001 taacgttgga tttgatgtta tagatattct tgctaaagaa tacaatatta gtgttactaa
    51061 aataaagcat aaagctttga ttggtgaagg gagagtaggt actgaaaaag tattattagt
    51121 taaaccacaa acttatatga atttaagtgg agaaacatta atagatatat ataaatatta
    51181 taaggttgat ttaagtaata tagtagtagt atatgatgat atagatttag aagttggaaa
    51241 gatacgtata agaaaaaaag gaagtggagg aactcataat ggcatgaaat ctataactaa
    51301 gtgcctaggt tcaaatgact ttccaagagt gagagtaggt gtatctaaac cagaagctgg
    51361 tcaagactta gcagactttg tactttctag atttagaaaa gaagaatctg ataacataaa
    51421 tgaagcatta gaaaaagcgg cagatgctat tgactcaata ataagagaaa atatagatat
    51481 gtctatgaac aaatataatg gatagtgaga gggagattta aatgaatgat gtttttttat
    51541 atcctttgca aaattcaaaa gagtataaag atataataaa ctgtataaaa aatacaaaag
    51601 gctcattatt ggttaatgga cttttaccag tacaaaaacc tcatatatcg tattctatat
    51661 ttaatgattt atcacgacaa atgattttta taacgagtag tgatttagaa gcaaagaaag
    51721 tatacgaaga tttaagtttt tatatggaag ataaagttga atatttaggt tttcaagata
    51781 tttattttta tcacttggat gcaaaggaca gaaacgaaga agcaaagaaa ttaaaagtat
    51841 tgttaaaact agcaaataaa gaaaaaatca ttttagtaac ttctattgag gcagttttaa
    51901 gaaaatacat accaaaacaa gttttgctcg atagtgtatc tcattataag gtgggagata
    51961 gcttagactt agaaaagtta actgagaaat tagtttcatt gggatatgaa agagtttcaa
    52021 aaatagaggg gtttggtcaa tttagtataa gaggtggaat tattgatgta ttttcacttg
    52081 aatatacaaa tccaattcgt atggaattat ttgatgatga gatagattcc atacgaactt
    52141 ttgacgtata ttcacaaaaa tcaattgata aattgcaaca attctctata actccatcta
    52201 gggaatttat ttatcccgaa aaaactacag atgcattagt taaattaaaa aaagaaacaa
    52261 ctaaaaatac tgatgaaggt acatttcaaa atatagatta tatatcaagt aagacttatt
    52321 ttgaaggtgc agagaactat atagattata tttatccaga agaaaacaaa agtatattta
    52381 cttatttagc agatgatgca atagtattta tcaatgatat aacgagactt aaagaaagat
    52441 gcgaaaatta tataaatgag tttagagaaa attataaatt aaatcttgaa agaggtctgg
    52501 ctattaaaaa ccaaggtaaa ttgttatatc actatacaga tttagagtac ttagtaaaag
    52561 acaagtctgt ggtattaaac tcgctattgc caaagtctat aaataacttt tctataaaat
    52621 ctataataaa ttttgaaagt agagaagttc ctacatttaa tggaaaggta gatttgcttg
    52681 tagaagaatt aaatcggctg aaatataatg gatacaaaat aattttagca acaaatacct
    52741 tagaaagagc aaataaatta ggaaaagatt tattggacaa aggcttagaa acgaccattt
    52801 ctaaagatag agatattgaa attaaatctt cacaagttat aattgtacct gcacacataa
    52861 acagtggttt tcagtataaa tctataaagt ttgttgttat aacagataac gaaatgatag
    52921 gtgtttataa aagagcgtct aagactagca ataaaaaagt taaaaaagga aagaaaatag
    52981 aatccttttt agatttaagt gttggagact atgtagttca tgaaaatagt ggtgtaggta
    53041 gatacacagg gattgaacaa attacagtca atgctattaa aaaagattat atgaaaatag
    53101 tatatcaagg tggagataat ctatatgtgc caatagacca gatggacaaa gtacaaaaat
    53161 atattggtgc agaagtagaa aaagttaagt taaataagct tggaacaaat gagtggacga
    53221 aagcaaaagc aaaagttaaa aaagaaattg aagatatgac aaaagacttg attgagcttt
    53281 atgcaaaacg tgaaaaaata caagggtata agttttcaaa agatacacct tggcaggcag
    53341 agtttgaatc gttgtttcca tatcaagaaa cagaagacca attaaaggct atagaagaaa
    53401 ctaaaaaaga tatggaatca agtaaggtaa tggataggct agtatgtgga gatgttggtt
    53461 atggaaaaac agaggtagct attagaagta tttttaaagc ttgtatggac caaaaacaag
    53521 ttgctgtatt ggttccaaca acaatattgg cccaacaaca ttataataca ttcaaagaga
    53581 ggtttgaaaa ttatcctttg agagtagaag ttttaagtag gtttaaaaca ccaaaacaac
    53641 aaaaacagat tattgaagat gctaaaaaag gattagtaga tattttaatt ggaacacata
    53701 gaataatatc caaagatata aatttaccaa acttaggtct tgtagtcatt gatgaagaac
    53761 aaagatttgg agtaaagcat aaagaagctt taaagaaaat taaatctaca gtagatgtac
    53821 ttacactttc agcaactcct ataccaagaa cattacatat gtctttaagt ggaataagag
    53881 acatgagtgt tatagaagaa cctccacaag aaagacatcc tgtaataaca tatgttacag
    53941 agagtaagga aagcgtaatt caagatgaga tagagagaga attaagtaga ggtggacagg
    54001 tattttttgt atacaataga gttgaacaca ttgaagaaat ggcaagtatg attcaaaaac
    54061 tcgtaccaga tgctagagtg gctgttgcac atggaagaat gacctctaaa tcattagaaa
    54121 atataatcct aggattttta aataaagatt atgatgtact agtctgtact acaataattg
    54181 aaactggtat ggacatatca aatgcaaata caatgattat atatgatgca gataaaatgg
    54241 gattggctca actttaccaa ttgagaggta gggttggaag aagttcaaga caaggatatg
    54301 catatctttt gtatgaaaaa gataaaactt taagtgagat agcggagaag agattaaaag
    54361 ctatcagaga atttacagag tttggttctg gttttaaaat agcaatgaga gaccttgaaa
    54421 taagaggagc aggaaatatt ttaggttctc aacaacatgg tcatatggca gttataggtt
    54481 atgatttgta cgttaaaatg cttaatgatg caattaaaaa agtcaaaggt gaacctattg
    54541 tggaggaaat tgatgttgaa atagatttaa gtgtaaatgc atacattcca gataattata
    54601 tcaaagatga gttgattaaa attgaaatgt ataagaaaat agcttctatt gaaaacaaag
    54661 aagacatgtt ggatatacaa gaagaacttg aggatagatt ctctgatata cctaaaccag
    54721 tccagacact tcttacaata gcttatataa aatcgttatg taagatatta aaaatagaaa
    54781 agataagaca attaaaagat gaaatattat tagttccaat aacaaagtat agaactaaac
    54841 agaaaatagg ttataatata gttacagaat tagaagaatt attagaaaag atgtgcaagg
    54901 taaaataact tgtaaattta agaagggatg ttttaaattt gaaaaaagta ataacattgg
    54961 taatagctat gattttggta gtatctgtga ctgcttgcag ttctagtaaa ggagaaactg
    55021 tggcaacagt tgaaggtaca aagatatcat cagatgaatt taaaaaaact atagctcttt
    55081 ataaagattc tatggaacaa acttatggaa aagatatatg ggataaggaa gttgaaaagg
    55141 gtgtaaaata caaggacaag tttaaagatt taattcttga ccaacttata actacagaag
    55201 taatatattc tcaagctaaa aaagataact tacttcctaa aaaagaggat gttgaaaaaa
    55261 gctttaaaga attaaaagac gctatgggta aagatgaaaa atataaagaa caacttaaga
    55321 aattaggtat agatgatgag tttttaagag accaacaaga gaaagattta gcaatgcaaa
    55381 actatcaaag taactttgct aaaaagacta aaatatcaga tgaagaaatg aaaaaatact
    55441 atgatacaca taaagatgaa tttaaaaaag atgaggtaga agcttctcat attttattga
    55501 aaacagtaga tgataataac aagccacttt cagataagga aaaagctgaa gctaagaaaa
    55561 aggctgaaga ggctcttaaa gaagttaaat caggtgagga ttttgcaaaa gtagcaaaaa
    55621 aatattcaca agatacttca gcaagtgatg gtggtaagtt aggattcttt tcaaggggtc
    55681 aaatggttgc tgaatttgaa gatgctgctt tttctatgaa aaagggtgaa gtatctgatt
    55741 tagttgaaac tcaatatgga taccacataa ttaaagtgac agacagaata aatgagcaaa
    55801 catcatttga agatgctaaa gaaactataa aagaccaact gttgaaaaat aaatatcaag
    55861 aacaaataga aaaattaact aaagaagcta aggtagaaaa agatgaaaaa gtaataaata
    55921 aaatcacaat ctaagactta aaaaaagagt aatatgctta aaaaagctat atctggataa
    55981 gatatagctt tttttgtata tttttcttaa caatggtaaa aataaactta aagtaattta
    56041 tggagggatt aaaaaatatg aaagcaacag gtatagttag aagaatagat gatcttggaa
    56101 gggtagttat cccaaaagag ataagaaaga cattaagaat tagagaagga gaccctttag
    56161 agatattcac agcaaaagat ggagaagtca tacttaaaaa atactctcca ataggtgaat
    56221 taaatgaatt ttcgcaagaa tatgctgaaa cattagctga agtactagga tatggagtgt
    56281 tgataacaga cttagattct ataatagctg tgtctaagct tcctaaaaaa gattataaag
    56341 aaaaaagtat aagtgatgag ttagaagcaa taataagtga aagaacagta aaatattcaa
    56401 aagataaaaa cattttacca ttattcaagg aagaccaaaa agaatatact agtcaagtta
    56461 tcatgcctat aattagtgca tctggtgact gtataggttc aattgtagtt gtttcaaagg
    56521 ataaagatac aattgcagaa agtgaagaaa aatctttaaa aattgctgct aactttttag
    56581 gaaaacaagt tcaataattt tatcataaag accttttaca tgaaggtctt ttgaagtttt
    56641 tgtgtaaaat attgaatata gcattaaaaa tatggtatat taaagtttgt tatataaaca
    56701 gtatggaggt tatgttatga acaataacaa aaataaagac tcctttctaa aaggagccct
    56761 tatacttggg ctagcaggtg taatcgtaaa aataatgggt ggatttttta ggattcccct
    56821 tggaaacatg attggttcag aaggaatggg atactatcag gctgcttatc ctgtgtatac
    56881 tctattttta acattagcta ctgctggatt tccaacagct gtggcaaaat tggtttcgga
    56941 aaaagttgca attggaaatt ttaaaggtgc aaataagata tttaaggtat cacatacagt
    57001 tttattcatt accggtataa tatcattttg tatattattt tttggagccg actacatagt
    57061 aacaaacgta atgaaaaatc caggtgcgtt atactctatg aaagccattg ctccagcatt
    57121 actatttgtt cctgcaatgt ctgcatatag aggatatttt caagggagac aagatatgac
    57181 taagattgct gtgtctcaag ttgcagagca attttttaga gttgtattag gtcttacttt
    57241 ggcctacttg cttatgaaga gtctaggtca gacttttggt gcagcaggtg ctatatcagg
    57301 ggctacaata ggttcaatag catctatgct ttatttggtg tttgcttata tgctagggag
    57361 aaaagagcgt agagcagaga tagatgcaag ccaaagattt aaagatgaaa gagtgtctta
    57421 tatttttaaa aagcttttaa ctgttgccat tcctataaca ataggagcat cagtaatgcc
    57481 acttgtaaat atgatagata atgttattgt aataagaaga cttatggaag caggctttac
    57541 atacaaagtg gcaaattcaa tgtttggtca attaacaggt atggcaatgg ccacaataaa
    57601 tttaccagca gtcataacaa ctgcaatgag tatgagctta gttccagcaa tttctaaagc
    57661 atatgcatta ggaaataagt caaaagctag aaaagatact aagagtgcag ttaaggtaac
    57721 tttacttata gtattgcctt gtgcgtttgg tatggcttct ttagcaatac caataatggg
    57781 tcttttattt ccacatgaac catcttctgt aggaactatt ttgtttactc ttactccatg
    57841 tgtattattt ttaggattaa tacagacatt gactggtata attcagggaa tgggaaaacc
    57901 aatagtacct gtaattgctt tatgtgttgg tatgctatgt aaaattgtaa taagttatac
    57961 tttaacaggt ataccagata ttaatgtact gggttcagca tttggtacag ttacagcata
    58021 ctttgtggca gccatgatta acttactata tgttaaaaaa cacatgaatg taaacttttc
    58081 taaaaaagaa tttataataa agccatttat aacagttatg acaatgttta taatggttaa
    58141 gttgagttat ggtgctttag ttggattctt aggaaacagc atatctacaa taattgcaat
    58201 atgtgttggt ggaattgtat atgtagtagt aatacttgga ataggtggaa ttaaaaaaga
    58261 agagattcta actatgccaa aaggtgataa attatataaa ttgttaaaaa aagttaaact
    58321 tataagataa tataggaata tatatacaaa taaaggaaat actatacaaa tagtaaatct
    58381 ccttatttgt ataataatat aaaaataaag tgaaatttgc taataggagt gatgttatgg
    58441 gtaagataag tattgtaggt cttggaccag gagactattc tcttataagc caaggtgtgt
    58501 tagaatcttt aataaatagc cctaaagttt tttttagaac agagaaacat ccaataattg
    58561 ataaacttaa agaaactata caatacactt ctttagacta cttttatgaa aaagaggaaa
    58621 attttgataa tgtttatttg aaaatatctg aatttatcat agaagaatca gcaaagggtg
    58681 acctagtgta tgctgttcct ggtcatccaa gagttgcaga gaagactgta agtataatag
    58741 agagattagc caatgaaaag cacatagcag tagaaatatt gccttctatg agctttgtag
    58801 acgctatgtt taactatttg gctatagacc catctgaggg atttaaactg gtagatgctt
    58861 ttgaaataga aaattcatat atagacttgg atacaagcat gataataact caggtatatg
    58921 ataaatttat agcatctaat gtaaagttaa aacttatgga acattatgac tataatcaag
    58981 aagtatgtat agtaaatgga gcaggtgtca aagatttaga aagtaaaaag tttataaagc
    59041 tttgtgaatt agacagaaat gaaaactttt ttgactattt aactagctta tatataccca
    59101 aaagttctaa aaagatgtat aatacagtac atgacttaga aataatagtt aatacactta
    59161 gaagtccatc tggatgtgaa tgggataaaa aacaaacaca tcaatcatta aaaaattctg
    59221 ttatagagga agcatatgaa ctttgtaatg caattgataa taatgatata gatgaaatgg
    59281 tagaagagtt aggtgatgtt cttttacagg ttatattcca ttgtcagata ggaaatgagg
    59341 agggctactt tgatttaaaa gaagtagtaa atggcatatg taaaaaatta attcatagac
    59401 atcctcatat atttagtggt gcaaaattag atatgtctaa gtttgagaaa acttgggaag
    59461 aattaaagaa agaagagaaa ggcgaaagta ctataacaga tggccttaga aggataccaa
    59521 aacatttacc agctcttatg aaggctagta aagttcaaca taaagcagca cttgtcggct
    59581 ttgattggga caatgtagaa gatgtattta aaaaaattga agaagaatat caggaattac
    59641 ttgacgaaca cagggtcggg aatataaaat acataaagga agagctaggc gatttattat
    59701 tttcgatagt aaatctagct agatttttag acatagactc aggagaagcc ttgaactgta
    59761 ctacagaaaa attcataaat agatttgact ttatagaaaa aagtgcaatg aacttgaata
    59821 aaaaattaga agacatgaca cttgaagaga tggatgagtt ttggaatcag gctaaaaaac
    59881 aataaaattg tggaaggaaa tttgtcaaaa atctagaact tttatcacaa agatagaagt
    59941 ctatattata aacattttta ggaggtaaat atcgtgaata aagctgaatt agtatcaaag
    60001 atggcagaaa aaagtggatt aacaaagaag gaagcagaag ctgcgttaaa cgcatttatg
    60061 agttctgttc aagatgcact agtaaataat gaaaaagttc aattagttgg atttggaaca
    60121 tttgagacaa gagaaagagc tgctagacaa ggaagaaatc caagagatcc agagcaagtt
    60181 atagatatac cagcttctaa agcaccagtt ttcaaagctg gaaaaggatt aaaggatata
    60241 ataaatggat aattagaaat cttgtgaaaa agtgtggata aatttgccac actttttcta
    60301 tagaaccaag gaaggtgata attatgagat tagataaatt tttaaaagta tctaggatta
    60361 taaaaagaag aactgttgct aaagatgcat gtgataaagg gattgtcact ataaatggaa
    60421 aagttgctaa atcttcttca gaggtgaata ttggagatac attagaaata caatttggag
    60481 agaagaagat gaagtttaag ataaatgaag taaaagagca tgtattaaaa aatgatgcaa
    60541 aagaaatgta cgaaatttta gaataaaatt aatagtcctc tagtatatta atagtagtat
    60601 tattgaaata tttactgggg ggatattatg gaacagaaca taactttgaa agatagatca
    60661 aagctggtta tttcgggagt cgagcacata tactctttta atgacaaaag agtagagctc
    60721 aaaacttctg taggcgagat ggtaattgaa ggcgaaaacc tagatatgag caagctaagt
    60781 atagacgaaa atataattag catagatgga actataaatt ctatggtata tgcaaagcct
    60841 aaaaagccac aagagagttt cttgaaaaag gtatttagat agatgatacc ttttactcaa
    60901 gatgtaagca ttttttatgc tactatttat ggtggaatac tcataggggt gttgtttgat
    60961 ttttatagag ggctaagagg gaattttaaa ttcatcaatt attttgctat aatctttgat
    61021 gtattgtttt ggtttctagc tacggttata atattcgtaa caataaacct tacagaattt
    61081 tttgatttaa gatattatca ttttgtggct ttgtttattg gttttatttt atactataac
    61141 accataagta aaattgtttt atcaattatc aataaaataa ttcgttttgt gagaaattct
    61201 tttaaaaaag ttacacatta catagtcagt tttttaaata atttgtatta cgttataatc
    61261 tattcactac acctactatt tgatattata ttttatatac caaacatatt tatagcaaca
    61321 agaaaaagta taaaaagaaa atcaaataaa aaattaaaga acaagaaaaa atcaaaacct
    61381 aagaagaaaa aaaataaaac taaaaaaagg gtgtaggaaa aatgaactta agaaaaaaat
    61441 tttcaggaca gattattgtt gtcagtttat ttttaggaat atcaattttt agtatgatga
    61501 caggatttgt atttgagtat acaaaagcta aggaatataa aaaagaaata gcaagtctaa
    61561 ataaacaatt aaaaaagact gaaatacaaa taaacagctt aaagaaagat gaaaaatcat
    61621 atgaaggaga cttagaggat atagcaagaa aaagattgaa tatggtaaaa ccaaatgaaa
    61681 cagtttatgt agacataaat cgttgattaa aacttgctaa taagtttaca gatgtattga
    61741 ttttaaaatt taagatttaa taaaaaagtc attcagttaa ggatggcttt ttgtttttat
    61801 tgaggaggga atttcataat gaaagtagga gctatagata ttgggacaaa ctcaatgaga
    61861 ttattgatag cagattatag agatgggaat tttataaaca gaaaaaaatt tgttaataca
    61921 actagaattg gttatggtgt ggatagtaaa ggatatataa aagaagatgc tatcaaaaga
    61981 aatataaaag cattaaaaga attttctgat aagtgtaatg atgaaaagtg tgaaaaaatt
    62041 tattgtatgg ggacatctgc tcttagagac agtaaaaatg gagattactt tgttaaatta
    62101 gctaaagaag aaactggaat agatgttgat atagttacgg gaatagaaga atcaaatttg
    62161 ggctttaagg gtgttttaga aggaatacaa ggtgatgata ctattattgt tatagatatt
    62221 ggaggaggtt caacagaatt tattgtaggt gattcagaag gaattaaatt taataaaagt
    62281 gagaatgtag gtgctcttag gatgacagag aggtttttga agcacgatat tattgaagat
    62341 gaagagtttg aagctatgag ttcatttata tatgatgaga ttgacaaaac gttaaatcat
    62401 ataaaagaca gaggattaaa aactcttata ggtataggag gtacgattac atcattatca
    62461 gcaatgaatc aagaattaga gatttactct atggaaaaaa tacataatag taaaatacac
    62521 aaaaaagaaa tagaagaaat tctacaaaaa ttaataaaga tgacattaag tgataaaaag
    62581 aacttaaaag ggctacaaga aaaacgtgcg gatattataa ctgctggtgt aaaaatattg
    62641 aatataataa tggaaaaatt agaaatagaa gaaataaccg taagtgaata cgataatttg
    62701 gaaggcttaa tatgtcaaaa gtcaaaaaaa atgtattaat attttttgat ttttaaaacc
    62761 gattatgaca aaaaaaatta ctcctctttg ttacaattct taatataaac aaaagaggag
    62821 gtttttttat gcaaagaagt gtagcagttg tgaagaataa gactgtaaaa ccaaatgtca
    62881 taaaattaat aagcggatat attgatttta ctacggcggc attcgctgtg atgggatttt
    62941 tacttagtag gtctattata gtagactctg tagctccttt aggaattgcc ttttttatat
    63001 gtgcatcaaa gattgataag tacaagatac ctgtattcat atcaacatta ttaggaatat
    63061 tgttatcatc taatgatttt ggaaatgtag caaaatatgc tgtgtgcctt acaatattta
    63121 tggctatgaa taaaaaatta aaattatcag attcaattgc taaggttgca tttataggtg
    63181 caataatact acttccaatc tccatgggac aagctttctt ttcaaatagg tatgtatatg
    63241 gtcttcttat agcaggagta gaagcaataa taatgtttat atctatatat gtgttttctt
    63301 atgggatagg tttaatggcc aatgtcaaca ataggatgtc tgtacggaca gaagaagcca
    63361 tatcaataag tttactgcta acctttagca taatgggaat aggagatata tctctgtttg
    63421 gaatatcaat aaggaccatt ttatcgaccg tattgatatt gctgacctca atagtaggtg
    63481 gagctaccat gggagcatct agtggtgtaa ttattggtgt agcatccatt ttaaataata
    63541 tgacatcagc tgtttatatg gggatatatt ctttttcagg attaataagt ggagcattta
    63601 ataaaataaa taaatatttc tgtatactag gatatattct aagttggaca ataatatacc
    63661 tatatacttc tggtattact tctaatatga tgcaattaag agatatacta ttaggttgtt
    63721 tgatagtact agtattgcca gagcgattat ttaataagat tgaaaaatta ataaaaagta
    63781 atgtggcttc aaatgaaatc gtatacgatt atattatgag aagcaaaaac ctaactaata
    63841 gcagattgaa cagtatttat aaaacttatg atgaccttgc agatacattt gataagataa
    63901 gagaaaaaga caaagtgcta gaccaaagag acatagctaa tgtaatagat atgattcata
    63961 atgatgaatg taaaagttgt agtatgagaa gaatgtgctg ggagtcaaga tttaatcata
    64021 catacactat gatatataac attcttgaaa aaattgagga gaaaggggag ttaagtctaa
    64081 acgatatacc taaaaatttt agaaaggaat gtatgaaacc agagtcaata gtgaaaatat
    64141 caaatcacta ttacaaaatg tttgtattag attatgattg gagtgtgaag ttttcagaaa
    64201 gtagaaagtt aatagcaaat cagataagaa gtatttcaaa atccattaaa tccttatctc
    64261 aagatttaga aggcgacata atgctagata tagaaaagga aaaaaatata tatgaacagt
    64321 tagaaagata tgatataaca gttgataaag taagttactt aacaaaaagt aacagtgagt
    64381 ttgaaatatc aatagaaaag aaaacttgcc atgatggatg tatgtgtgaa gataaaattg
    64441 taaatataat ttcagaccta gtaggggaaa atatgtctgt tagaaaaata ggatgtcact
    64501 gtttaggagg taaatgcaag gcaacattcg ttaaatctca aaaatataag gctgttacag
    64561 aagtttcagc aatgtcaagg gatgggcata tcctttgtgg agacaattac acatacatgg
    64621 agataaatga tggtaaatac atgatggcta taagtgatgg tatgggaaaa ggtaaaaaag
    64681 catatgaaga atcttctgcc actattgata tactggaaaa aatgatagat gcaaaaatta
    64741 aagatgagat agtcattgat actataaata atatgttgtt gttaaaatct tcagaagaga
    64801 tgttttcaac tctggatttg ggaattttag atttaaaacg aggttgttta gaaactataa
    64861 agatgggagc gtgttctact tatataaaaa gagaggatgg agaagttgac ttaatatcat
    64921 catcatcatt acctgtgggt atattatcag atgtaaaaat tgatagaaaa aatgtaaaag
    64981 ttaaggaagg agactatgtt ataatggttt ctgatggaat tgtagatgca ggaagaaata
    65041 acaatttagg agacaattgg ttaatatact tcttaaagaa tatagagact acaaatccaa
    65101 aggaaatttc aaatttaata ttggatagag cattagagtt acaagcgtta caaatcgaag
    65161 atgacatgac tgttttagtt acgaaaatat gtacaaaata aggtttacaa gattatgtgt
    65221 ataagatgtg gataacttgt gtataatatg ttaatagact tttgaaaaaa gtatagttat
    65281 taacaaaaat aacatataaa tcaacaaaat ttgttgataa gtatggcaga aatgttaata
    65341 aaatgtaaaa aaagaaaaaa caaaagctat tatcaaaaga gattcatgtt gaaataacta
    65401 aatttctaag taaagaaaac ctgtgaatat gttgattatt atgtggataa ctattaattc
    65461 gatatttatt tatatagtat gaataattga ataatatatc taaaaaaagc catcctatta
    65521 ttaagtaaac ttattgaaag gatggctttt tatgaataga aaattgtgca aagcaataat
    65581 acctttattt atttctattt tttgcatgtt aataataagt ataaaagctg accaaggata
    65641 tcaaaagaat aatgacagag caattactgt catgaataat aatgatactg aagatgatgc
    65701 tgaaaaaaaa caagaaatag actatgaaaa aacatgttgg aatttgcaat ctttgtttaa
    65761 aagtgatgac caatggaaaa aagaacttaa gagttttgat aaagatacta aagagttgaa
    65821 aaattacata ggtaaagtaa caaaatcgcc aacacatttg tcttttgcct taaacattaa
    65881 agaaaaactt gatataagac taaataaact ttctgcctat gtaaaattaa aacaagatac
    65941 taataaaaat tcgtataagt acttagatat gaatgatagt atgagtaaat cctatgggaa
    66001 ttatatgggg atttgttcag atttagagtt agaaatacta aaattatcaa acaaagatta
    66061 caagaaaatt atttcaaata aaaatataaa taggaaatat ggtgcatatt taagagatat
    66121 aagaaggaat aaagtacatt atttggatga taaatcagaa gatattctaa gcaaagtatc
    66181 ttcaataagt agtcttccaa gccaagtgta tgaattattt agaaatatgg atagaaaaac
    66241 taatttgaca ccagctcaat atgcgagtga attagagtca tcagatagag aaaatagaaa
    66301 aaaagcttat caagatgaac ttataactta caatgataat ataaatacaa ttgcaggttt
    66361 aattactggt caagttaaaa agaatatttt ttattctcag gaaagaggtt atgagtcttc
    66421 tttagaaatg tacctggaat ctgataatgt agatgaaaaa gtatacaata atttgataag
    66481 gactgtaaat agtaatatgg acagtctaca caaatatata gatttaagaa aaaaagtatt
    66541 aaaattagat aaggttcatt catatgatat gtttgtgcct atggttaagg ctgttgataa
    66601 taatattaat tatgaaaagg cacaaagtat agtatattca gcgttgtcac ctttaggaaa
    66661 agaatacaat gatgtagtat ataaagcttt caatgaaaaa tggatagatg tttattcaca
    66721 tgaaaataaa gtaagtggtg gatactgctt atctgtttat gaaaatcatc catatatact
    66781 tttaaattat aataattcat taggttcagt ttcgacttta tcacatgagc ttggacatgc
    66841 tgtatatgaa tatttaagtt ctaagaatca gaattatttt aattcaaatc cgtctatatt
    66901 tactcacgaa gttgcatcta caacgaatga agcattactt tacgagatgc ttataaaaga
    66961 agctaaaggc aatgatgaaa aagcttatta tataacacag tatttagact tgataaaaga
    67021 tactctttat acacaaacta tgtatgctga atttgaaaaa actatacacg agttagtaga
    67081 aaaaggaaaa agtgtaaacg cattagtatt aaatgatgtt tggggacaac ttcttaaaaa
    67141 atattatgga caaagctatg aattagacca attatctaag gtcggatggg ctagaatccc
    67201 acatttttat aatagtttct atgtctataa atatgctaca ggttgtagtg caggagtaag
    67261 ttttgcccaa gacatcctaa agaatggttc agataactat atgagctttc ttaaaaaggg
    67321 aagttcagat tatccaataa acttgttaaa atcaagtggc ataaatttaa ctaatacaaa
    67381 acccatagaa aatacaatca aaaaatttga tagtttagta gcagaacttg aaaagctatt
    67441 ataaacatta ttgtaatcca catggtaaat atatcgaatt aatgataaaa tatactaaaa
    67501 gtttaaagtc ctatcaagat aggacttttt atttattaat tagtgggaga tgattctatg
    67561 caagttaaag ttaaaaaggc tgtaatacca gcagcaggtt taggaactag atttttgcca
    67621 gctacaaagg cacaaccaaa agagatgtta ccaatagttg ataagccaac tctacaatac
    67681 ataatagaag aagctgtggc ctcaggaata gaggaaatac taataataac aggtagaaat
    67741 aaaaaatcta ttgaagacca ctttgataaa tctgtagaat tggaacttga tttagagaaa
    67801 aaaggtaaga aagaattgtt ggaggtagta caaaacatat ctaacatgat taacatacat
    67861 tatataagac aaaaagagcc aaaagggttg ggagatgcaa tttattgtgc gaggcatttt
    67921 ataggtgatg agccgtttgc agtaatgtta ggggatgata ttgtagataa tgatgtacct
    67981 tgtctaaaac aactaacaga tgcatatgag gaatatagaa ctacaatatt gggtgttcaa
    68041 aaggtaaatc aagaagatac taataaatat gggataatag aagcaaaaaa tatagaaggt
    68101 agagtttaca aggtaaaaga catggtagaa aagccagagt caggaaaagc tccttcaaat
    68161 attgctattt taggtagata tataataact cctgaaatct ttgatattct taaggattta
    68221 ccaccaggta aaggtggaga ggtacaactt acagatgctt taaaaatatt atctaagaaa
    68281 gaagctatgt atgcatacaa ttttgaaggc aagagatatg atgttgggga caagctagga
    68341 tttttagaag ctactgttga ctttgctcta aagaaagaag accttaagga agattttata
    68401 aaatatttga aacatgtatg tagtgaattt gataaaaata acaatgtgtt atacaataat
    68461 acagatgaaa aaatagattt aattgaagtc aatgaagcta gagaacttga aattcaaaaa
    68521 taattaatga aaggtgatgt atggtggcaa aatcaagtca gaaaagaatt aatagaataa
    68581 tagctgttgg gattgtggga atcctcgtaa taacgagtat aacagctgtt ttgagtatga
    68641 ttgcaactat gtaataagat aaatgacagc agttgatata cataaatata aaaaccatat
    68701 ataacttgat gtagtcaaaa acttacaata ttttagttat atatggtttt tagaatttat
    68761 aaatgtaaaa aaaaattttt ataatagttg catattttaa aggaaaatat tattataaga
    68821 tataaatata gtgataaatt tataaaaacg tgctaagatt ggacttgaaa tacagtaata
    68881 tagtaggtaa taatgtttta aattttattt attgaccata atatataaat aatgatatta
    68941 ttagacttaa ctgtttaaat aaaacttttc tttttcatgc cttcaatttc caaaataagt
    69001 atgtatataa atgaatatat agatgaggag gatttttttg attttagatg ataaagtatt
    69061 agaaggatta ggtagtaaga ccttagttga gctacgagag atagctaaag aattaaaaat
    69121 aaaatcaatt actacatata agaaaaatga gttaattgag attataaatt ccaaaagtaa
    69181 aaatgaggaa aaagtaaacg aagagactaa agaaaaaaat gaagatatta aagaagacat
    69241 aaagaataga aaagaaaata tagagcgtga aagtatagaa aaagaagttg aatataagag
    69301 ccctaccaaa tcatacaaca agaaagaaat agatacccaa aatatttccc aaaaccaaga
    69361 acatagaaat caaagaaatg actataataa gacaacgagt gtaaatgata gtaataagtc
    69421 atcaaatata tctaatagaa tggtcagaaa taataataaa aactattata tgcctaaaca
    69481 agttgatgaa tctaagatag tagatgaatt taacacatca aaagaggatg aagtagtagg
    69541 tgtacttgaa attctaccag atggatttgg ttttttaaga ggttcaaatt atttgtctac
    69601 tgaaggagat gtttacgttt caccatctca aataagaaga tttaatatga aaacaggaga
    69661 caagattaag ggaataacta gacatccaaa aagtggagag aaatttagag cacttttata
    69721 tgttcaaaaa ataaatgatg aaaaccctga cacagctata caaagaaatg cgtttgagac
    69781 attaacacca atatttccag aagaacgact tacactggaa actaatagaa atgaaatagc
    69841 tacaagaatt atagatttaa tttcacctat aggaaaagga caaagaggat tgatagtagc
    69901 acctccaaaa gctgggaaaa cagttctttt aaaaagcgtt gcaaatagca tagctaaaaa
    69961 tcatccaaat gttgaactta tagtactcct tatagatgaa agaccagagg aagttactga
    70021 tatgaaagaa tctattgaag gagacgttat atattccact tttgaccaag tatcaagtca
    70081 tcatgtcaag gttgcagaga tggtgttaaa tagagctcaa agattagttg aacatggtaa
    70141 agatgtagta attttactag atagtataac tagattggca agggcatata atcttacaat
    70201 atctcctaca ggtagaactt tatctggagg tattgaccct ggtgcacttc atggacctaa
    70261 aaagttcttt ggtgcagcaa ggaatattag acagggtggt tctttgacaa tattaggaac
    70321 agcattggtt gaaactggtt ctaggatgga tgatgtaata tttgaggaat ttaaaggtac
    70381 aggaaatatg gagctacatt tagatagaaa attagcagaa aaaagaatat tccctgcaat
    70441 agatatttac aagtctggta caagaagaga tgatttattg cttgatgatg aagaaaagac
    70501 tgctctttgg agattaagaa gagaaatgag taataattca gtaatggaaa ttacagataa
    70561 agtcattgaa cttataaaga gaactaagga caataaagag tttgtaaaat caataaagaa
    70621 tttgtaaaat caataataca aatgcaaata tggattatat aaactaatag aaaaatcact
    70681 tgaatggcat aataagttgt gctataataa tgtagttgat aatgtaaaaa gaaagttaat
    70741 ataattaatt tttttaaata aagagaagag gtgactataa tgcaaaagga aatacaacca
    70801 aaatacaatc cagttgaagt gcgttgtgct tgtgggaaca catttgttgc tggttcaact
    70861 aaggacgaaa taaaagttga aatatgttca gagtgccatc cattctatac aggaaaacaa
    70921 aagaacatag aaaaaggtgg aagaatcgac aaattcaaga aaagattcaa aatggactaa
    70981 tttttataaa agtggagttg gaggaagcca actcctattt tattacaaaa aaacattcat
    71041 attctacttt aaattgtctt tttgtattat aataataaat atgtaaaatt gagtattcta
    71101 aatacaataa aatgaggtga gtggatggca aaacaagctg taggtgggca agctgttatt
    71161 gaaggtgtaa tgatgcagtc aaaagacaaa agagcggtag ctgttagaaa aagtgacgga
    71221 gaaatagcac taaaagaaga tagaataaaa agttgggtaa gagataagaa tatagataag
    71281 ataccttttg ttagaggttc ttttgttatg atagatacaa tgattcaagg cataaaaagc
    71341 ttaaactttt cttcagagtt ttttatggaa gaagctgaag aggataaatt tgatttattt
    71401 ataaagaaaa tttttaaaga taaggcaaat gatataatta taatattttc attggtcata
    71461 gcaatgttac tttctgctgg attattcatt tttataccta cattggtagg aggagctttt
    71521 tctaaagtaa tgcctaatga ttttatgctt aatttaatag aaggaatcat aaggatagct
    71581 atattatttg catatatagt attgatttca cgaagtaagg atatagaaag agtctttcaa
    71641 tatcatggag cagaacataa atctatatat tgctatgaaa atgatttaga acttacagta
    71701 gagaatgcta gaaaatttaa aagattacat cctagatgtg gtacaaattt cctatttata
    71761 gttatggctg tatcaataat attgtttgca ttttttggtt ggccaaatcc aattcttaga
    71821 atatttatga gaattatatg tgtgcctata gtagcaggtt tatcttatga ggtaattaga
    71881 gttcttggga aatatgataa tggatttact aaaattattg catatccagg aatgatgttg
    71941 caatatttta caacaaaaga gcctgatgat gagcaattag aggttgcttt ggaagcattg
    72001 aaagcagtag tagattagag aaaaggatat ttgttatgac gataaaagat ataattatta
    72061 aatattcaga taaactaaaa gatataagtg atactccaag attagataca gagttattgt
    72121 tacaaaaaac attgggtgtt gatagattat atattcactt aaatctgaat aaagagctaa
    72181 ctgaagaaca aaaaacaaaa tttatgggtt ttgcagaaga aagattaaat ggaagaccaa
    72241 tagcatatat agttgaaaat agggagttta tgggattaga tttttttgtt aaggaaggcg
    72301 tattgattcc aagaccagat acagaaactt tagtagaaga aataattgaa atatgtagag
    72361 aaaaaaaaga tgtaagtata ttagatatag gaactggttc tggagctatt acaataagtt
    72421 tagcaaagta cgttgaaaat tctaaaatca tgtcttttga tatatcagag acagcattag
    72481 aaatagctaa aaaaaatgct attataaatg aagttggtga aaaaataaag tatattaatt
    72541 ctgatttatt tacagcaata agtgatagta acataaaatt cgatatcata gtttcaaatc
    72601 caccatatat taaaaaacaa gatatagaaa ctctgcacaa acaagttaaa gattatgaac
    72661 catataatgc tcttgaaggt ggagaagatg gattagactt ttatagaaga ataacagaac
    72721 aaggtaagaa atatttaaat aagtgtggaa tattagcata tgaagttggt cataatcaag
    72781 ctgaagatgt aataaatatt atgaaaagta atggatataa aaaaatatac acaaagaagg
    72841 atattcaagg cattgataga gttgttatag gttacaatat atgatataat caacaattga
    72901 tatgttacat ttaatcgagg tgaaagtatg ttaaaaaaat tagaggtatt ggaagataca
    72961 tataaagact taagtgaaaa aataggtgat ccggatgtaa taaatgatca aaaagtttgg
    73021 cagaaatata taaaagaaca tgctgacttg gaacctattg ttatgaaata cagagagtat
    73081 aaaagcgttt tagatagtat aaaagaatca aaagaaattt tacaagaaga gtcagatgaa
    73141 gaattaagag aattagctaa aatggagtta gctgagatgg aagaaaaagt agcacctctg
    73201 gaggaagaaa taaaaatact attattgcct aaagacccta atgatgataa gaacgttata
    73261 gttgaaatta gaggtggagc tggaggagat gaagcagctc tatttgctgg tgatttattt
    73321 agaatgtact caaggtatgc tgaaagaaga agatggaaaa tagaattatt gagtgcaagt
    73381 gatactggag ttggtggata taaagaagta tcttttatga taaaaggtaa aggtgcttat
    73441 tcaagattaa agtatgaatc tggagttcat agagttcaaa gaataccatc aactgaatct
    73501 ggtggaagaa tacacacatc aacttctact gttgcagtat taccagaagt tgaagatgta
    73561 gaggttgaaa taaatccaaa tgatttaaga atagatgttt ttcgttcttc gggtaatgga
    73621 ggacaaagtg tcaatactac tgactctgct gttagggtaa cacatatacc tacaggtgaa
    73681 gtagtatctt gtcaagatgg aaaatcacaa ttaaaaaata aagagcaagc tttaaaaata
    73741 ttaaaagcta gactttacga taaagcattg gcagaacaac acaaagatat agcagcagaa
    73801 agaaaaagcc aagtcggaac aggagacagg tcagaaagaa taagaacata taatttccct
    73861 caaggtagaa taagtgacca tagaataaat ttaactttat ataagttaga tgcattctta
    73921 gatggagata tagatgaaat gatagatgct ttaattactg ttgaccaaac agaaaaaatg
    73981 actgcaatat aagtaatgtt ttaaagaagc tgtttcttcc tagaaattat tttctatttt
    74041 gaaacagcta ttttgcattt taggtcatgt tatcatattc tattgtatat aattgttata
    74101 tacaagtata ggagggttat atgatactaa aagtaacaat aattgggctt ttggcaggtg
    74161 ttatagggac aggattagga ggagtaatat cagccatttt taaaagagag gtcgataaat
    74221 atctaagttt ttttatggga ttatctggtg gaataatgtt ggctgtagtg gtgtttgatt
    74281 taatgaaaga atccatggac aaaatgggga taatcaatac agttatattt acgtttgttg
    74341 gagctctcat aactatgtac ataaaaacaa aattagatgt gtctggaaat atggcatctg
    74401 gatatcttat attcataagt atattactac ataatttacc agaaggacta gccattggtt
    74461 cttcttttat gtcaactgaa agtttaggta ttacacttgc tatagttata ggtctacata
    74521 atataccaga agggttagct atggcattag gcttagtttg caataaaatg aaactaagta
    74581 aagttatttt gtttactgta atagctggat tacctatggg tctaggaagt tttttaggtg
    74641 tttattttgg aggagtattt acttctctta taggagtatt tcttgctaca gcaggaggta
    74701 ctatgatgta tgttgtattg gaagaaattt ttccacattc aaaaagtgtg tattgtataa
    74761 ttggtttctt gttaggtaca atgattgtaa attatatata aaattaaaat gaaagcaggc
    74821 atacaaaaga tgaaaactat tataagtaat attgatataa ataatattga ttatgaggaa
    74881 ataaaaatac aagcaaaact tcttagagaa ggtaaaacag ttatttttcc aactgagaca
    74941 gtatatgggt tgggtgcaaa tgcattagat gaaaatgcag taaagaagat ttatgaagct
    75001 aaaggaagac ctagtgacaa tccattgata gtccatatat atgaaaaaga agaagtatat
    75061 gacttagcca aagatataag tgataaagct aaacttgtta tagaaaagct ttggccagga
    75121 cctataacaa ttatattaaa taaaaaagat ataattccat acaaaactag tggagggctt
    75181 gatacagttg caataaggat gccttctaat gttattgcca gggcaataat aaaagaagct
    75241 ggtataccta ttgcagctcc ttctgcaaat atctcaggtc gcccatctcc aacaaaagca
    75301 aaacatgtat atgaagagat gaatggaaga gtggatggaa tagttttagg aggagacagt
    75361 aattttggat tggagtcaac tgtattggat ttaacagaag agactcctat gatactgaga
    75421 ccaggaagta taactaaaga agttttagag gaacttcttg gagaagtaaa gcttgaccca
    75481 tcattaagta aaaaagaaga taatcaaaaa gctaaagctc ctggaatgaa atataaacat
    75541 tattctccaa atgcagatgt atatataata tctggaaaaa gagaaaatgt agcaacaaag
    75601 attaatgata tgataaaatc taatagagac aaaggtctaa agacaggtgt aatgtgtatt
    75661 agtagaaacc gagagtttta tgatggagaa gtaatcgatt taggaaactc tcttgaagaa
    75721 gttgcaagta atctgtttga tgctcttata gaaatggaca aaaagggtgt tgatgtcata
    75781 tattcagaag agttccccaa gactggagtt ggacaagcaa ttatgaatag actactgaag
    75841 tcagcaggat acaaagtgat aaaggcttaa gagggagttg taaaatatga atatacttat
    75901 tgtgtgtaca ggtaatactt gtagaagtcc tatggctgag gctatactaa ggaaagcaat
    75961 taaagaatct ggaagaagta ttgaagaata ttctatatca tcagcaggta tatctacagc
    76021 aaatggaatg ggtgcttctg aaaattctat agaagtacta aaagaaatcg gtatagactt
    76081 atcaaatcat agaagtaaag taattactaa aaaattaatt gatgaatcag atataatact
    76141 aacaatgact aaatctcata aagaaatttt agtacaagca gttccaaaat gcaaagaaaa
    76201 agtgtatact tttaaagggt ttgcaaataa aaatgaggaa gatatatctg acccatttgg
    76261 tggaaatttg gatatttata gaagcactat gagagaaata atgtattctg tcaacgaaat
    76321 agtaaaaaaa atatgaaacg gaggataaac aaatgaagat aggattaggc tgtgaccatg
    76381 gaggatataa tttaaaaaaa gaaataataa gctatttaga aagtaaaggt atagagtgtg
    76441 tagattatgg aactaataat gctacagatt ctgttgatta tcctgtttat ggagaaatag
    76501 ttgcaaattc agttataaat aaagaagtag attatggaat attatgttgt ggtacaggga
    76561 taggaatatc tttagctgct aataaggttc ctgggataag atgtgcagtt gtatcagatg
    76621 tattttctgc aaaaatgtca aaagcacata atgatgcaaa tatgttatca ttaggcgaaa
    76681 gagttttagg aaaaggtcta gcacttgaga tagttgaagc atggattaat acggattttg
    76741 aaggagatag acatgctaga agagtaaaca tgattaaatc aatagaagaa aaacataata
    76801 aataataaaa attacagttt tatcaggagg aattatcaaa atgagcaaag tggtagagac
    76861 aaaccatcca ttaatacaac ataaattaac tttaatgaga gataaaaata ctggttctaa
    76921 agactttaga gagcttttaa ctgaaattgc aatgttaatg gggtatgaaa taacaaaaga
    76981 tataccatta aaagatgtag aaatagaaac tcctattcaa aaaacatcat ctaaagtagt
    77041 tgcaggtaaa aaattagcaa taattccaat tttaagagca ggtcttggaa tggtagatgg
    77101 attagtaagc ttaatgccag cagcaaaagt tggacatgta ggactatata gagacccaga
    77161 aacattaaaa ccagttgaat attattgcaa gcttcctcaa gacataggag aaagagatat
    77221 aatagtagtt gaccctatgc ttgcaacagg gggttctgct gtagcagcta tagatttact
    77281 taagtctaaa ggagctaaaa gtataaaatt agctaattta gtagctgcac cagaaggtat
    77341 agcagaagtg caaaaatatc atgatgatgt tgatatatat gttgcatcag ttgacgaaag
    77401 attaaatgaa catggatata taattcctgg tcttggtgat gctggagata gattgtttgg
    77461 aactaaataa aaataaataa ctataaatat ttattaggga ctttcttata tagtgtatat
    77521 aattttatgt aagaaggttc ttttttatat attttttctc aaaataggaa ttattgaatt
    77581 gataaatttc tcgaattgag aataaaaagt ttttaccaat taaaaaagat tgcttatttt
    77641 acaaggtttt atagaatagt agtctatttt aatgtggcat gttagttgct tacgattaag
    77701 attataggta ttaagtgtat tagttaaatt gagaattgaa tattaataat attattggga
    77761 gtggtaatac atgaagaatt gtatagtagt aagaggggct ggagatttag caacagcagt
    77821 tattcataaa ttacacaaca gtggttttaa agtagttgcg ttagaaatag aagagccatt
    77881 agctataaga aggcaaattt ctttttgtga ggctgtttat gaaaaaaaag taactgttga
    77941 aggtgtagaa tgtatatttt gcaatactga aaaagaaata gaggaagttt tatctcaaca
    78001 taaagtagcc ttgattatag acccaaaagg agaaaaatta tctaaattaa atccaatcgt
    78061 tttggttgat ggaatactcg ctaagaaaaa cttaggtaca actaaagata tggcaccact
    78121 tacaatagct ttaggtcctg gattttgtgc aggagaagat gtagatgttg ttatagagac
    78181 aatgagaggt cataatctag gaagaataat aactaatggt agagcagaaa aaaatacagg
    78241 agtaccagga gcaataaaag gtttttctaa agagagagtt atgcattcac agtatgatgg
    78301 cataatggaa aatgtatgta agataggtga tacagttgaa aagggagacc tactttgcta
    78361 tattaataat tatgaaaaaa aacatgaagt tagagcaaca atatctggag tccttagagg
    78421 tttattaaag gatggagcaa aggtaaacaa aaatttaaaa atactagaca tagaccctag
    78481 aaaagaagaa gttaagaatg cttttacaat atcagataaa gctagatgta tagctggagg
    78541 ggttttagaa gccatactaa acaatgggat ttatccccaa aattaattta tattagataa
    78601 agctattaat attttattaa gatgatataa taaatttaat agattaaaga gagcatatga
    78661 cgggtattta aaatttaaat ggtaaaaatg ctcttttttt attggacatt caattaacat
    78721 gtgtatataa tataaaaata agtatttatt taggttgaaa tctaataaat atataatacc
    78781 agtacataag caaagaggag aaaagtaaat tatgagacca tcatgggatg aatacttcat
    78841 ggaaattgca gaagtagtga aaaagcgttc aacttgtatt agaagacaag taggagctgt
    78901 aattgtaaga gacaaacaaa tattaacaac tggatataat ggttctccga gaaatcttga
    78961 acactgtgaa aatattggat gtaagaggca ggaattaaat attccctcag gagaaaggca
    79021 tgaattatgc agagcattac atgctgaaca aaatgcgata atacaagctg ctcataatgg
    79081 tattagtgta gatggggcaa ctttgtatgt tactacaaga ccttgtgttt tgtgtgcaaa
    79141 aatgtgcata aatgcaggta tattgaaaat tgtttatgaa ggtgattatc cagatgatat
    79201 gtctacagaa ttattaaaag aagcaggaat agaactcata aaattttagt ggataaaatt
    79261 tatatgacaa taaatgtcaa attatgacac tgaaatacaa tggtatcaaa tgattaaaag
    79321 aaagtatttg aaaaatcatc agattagtag taagatatat tttataatta aataaattta
    79381 tgagatagat taattacatg ttatttattt tataataatg agggatacta tttatgagta
    79441 aaagaaatac acatacagaa attgcaaagt tgtttagttt aataagtcaa ataggattga
    79501 tgattgtaat atcaatatta ggatgtactt tcttaggaaa atttttagat agtaaattga
    79561 atactactcc agttctgaca ataatatttt tattgttagg tgttggaggt gcttttagtg
    79621 gtgtttataa aactctaata gtatatacac gaaggaagtg atatattgga tataaaatta
    79681 cttaaccagg taaggtcagt aacaaaaggt atagtaatat ttgatgtagt tttaattgtg
    79741 ctaatgttga taacatcaac attaagtaaa ccagtattat taggacttat atttggctct
    79801 ataatagcta tgttaaattt tagattattg gcgatatcac tggaaaaatc agtgacattt
    79861 cctgctggga aggcacaagc ttatgcatca gcacaatatg ctgttagatt atttataatg
    79921 gcagtcgttc taattgcatc agctacagta ccacatttaa atataatcgg aacagcattg
    79981 ggattattga gcacaaagtt tgtcatatta tcaaaaaact ttataaataa attaaagagg
    80041 aaggaggcat aagtatgaat caagcgcatt attatctcat aggaaacttt aagattagtg
    80101 aaacaatact agtaagttgg ggaataatgg cctttttagc gatagcatct tattttttga
    80161 ctagaaactt aaaaaaagtt ccaactagta aagttcaaat attcttagaa tttgcagtag
    80221 gtggtcttgc taaaatggtt acagatgtta tgggtaaaaa tacagtaaaa agaatgccat
    80281 atatgatacc atacatagga agcttgtttt tatttttcgc atgttcaaat ttaagcccat
    80341 tacttggatt aaggtcacca acaaccgact tagacacaac tgctgcatgg gcaatgatta
    80401 cattttttat gatttatttt gcaggagtta aatttaaggg gttatcatac tttaaagaat
    80461 tggctcaacc acttgccata atgttaccaa tcaatattat aggtgagtta gctagaccaa
    80521 tatcattaag tttccgtcca tttgggaata ttttaggtgg aacaataata atgggtctgt
    80581 tttatcaact tttaggtttt atatctagtt taataccagg attatcaata ccaattggag
    80641 aaatattaat accagtccca ttacacttgt actttgactt atttgcagga ttgttacaag
    80701 catatatatt tataatgtta acaatggtat ttatatcaag tgcaggagag ttagattaag
    80761 aaatcaactt atattaagat aaaaataaaa taatttaaaa aattaaagtt ttaaggagga
    80821 aataattatg gaaacagcaa tagtagcggc agcatcagca ataggagcag ggatagcagt
    80881 tgcaacaggt ataggtgcag gtataggtca aggtatagca gcagctaaag ctgcagaagc
    80941 agtaggaaac caaccagaag ctaaaggtga tataacatca actttattac taggagttgc
    81001 tatagcagag tcttcagcaa tatatggttt ggttatatca ataatacttc tattcgtaaa
    81061 tccattcttt aaatacttag gaatgtagat ttagtcctta aatattttga gataggttta
    81121 taggtaaatc atctcaaact tataatcatg agatgaactt tatcatctcg tgattataag
    81181 tagttatgat ttatggaaag gaggataatt atggaaaaag cactagtagg tataacgtgg
    81241 gaatttgtgt tccaaattgt taatactttt ataatatttt tacttctgag aaagctttta
    81301 ttcaagccag tattaaatat aattgaatca agagaaaatg atattaaaag tgatttggca
    81361 gaaggcgaaa aagcaaaaaa tgaaggttta gctctgaaaa aagaatatga gtcaaaaatc
    81421 aattttgcca aggatgaagg tcaagaaatc ataaaacaag caactataag agcagagcag
    81481 aaatcagatg atatagtaaa tactgcaaag aaagatgctc ttgatataaa agaaaaagca
    81541 aacaaagata tagaacaaga aagacaaaag gttataaatg aaatcaaaaa tgatatatct
    81601 aacatagcac tacttgcagc atctaaagtc attgaaaaag atttagataa atctaaacat
    81661 gaagaattga tagaaaactt tataaaagag gtaggggaag ctaaatgata aatgtaatag
    81721 caaatagata tgccgaagcc ctatttcaat taggagaaga agaaaattca actgatgtct
    81781 tattcaaaga actagaaaaa gtagtagata tgatgactaa agttagtaaa gatttctaca
    81841 aagttttaaa atcaccatta gtttcaaaat cagaaaagaa aaacttggta gaaattattt
    81901 ttagtaaaga agtaagttct aacataaaaa actttttaaa agttttagta gataaagata
    81961 gaatatcata tttagaagat atcgaattag cttataaaga attattaaat aagaaaaaca
    82021 atgtaattga tggagtagca ataagtgcta ttccaatgag tgaaacagat attaaagaac
    82081 ttgaagtcaa actttcaaat aaatacaaca aaaatgttac tatagaaaat gttgttgaca
    82141 agactatact agggggagtt ctagttagaa ttggaaatga acaaatagat ggcactgtga
    82201 aaactcgtct tgataagatg aaagaaaagc tatctgaagt aatatcttaa gaatggcggt
    82261 gaacccatga acttaaaacc tgaagaaata agttctataa ttaaacagca aataaaaaat
    82321 tatgagaata aagttgagtt gacagataca ggtagtgttt taacagttgg ggatggtata
    82381 gcgagtgtat atggattaga aaaagctatg tctggtgagt tgctagagtt cccaggtgaa
    82441 atatatggta tggcacttaa cttggaagaa gaagtagttg gagctgttat ccttggagat
    82501 gacagtgaaa taaaagaagg cgatatagtt aagagaactg gaagaatagt tgaagttcca
    82561 gttggagaag ctttaatagg tagagttgta aactcattag gtcagccaat agatggaaaa
    82621 ggacctatag cgtacacaaa aactagacca gttgaatctg aggcacctgg tataatagat
    82681 agaaggtctg tttatgaacc attacaaaca ggaatcaaat caatagattc aatgatacca
    82741 attggtagag gtcaaagaga gttaataata ggtgacagac aaactggtaa aacatctata
    82801 gttattgaca ctatactaaa tcaaaaagga aaagatgtta tctgtatata tgtagcaatt
    82861 ggacaaaaac gttctactat agctcaatta gttagctctt tagaaaaagg tggagctttg
    82921 gattatacaa tagtagtttc agcaacagca tctgaatcag caccacttca atatatagca
    82981 ccatatgctg gagcagctat gggtgaagaa tttatgtaca atgggaaaca tgtacttata
    83041 gtgtatgatg atttaagtaa acaagctgtt gcatatagag aaatgtcatt gttacttaga
    83101 agaccaccag gacgtgaggc atatcctgga gatgtattct atttacattc aagattactt
    83161 gaaagagcag ctaagttatc tgatgaattg ggtggaggtt caatgactgc cttgcctata
    83221 atagaaactc aagctggtga cgtttctgca tatataccaa caaatgttat atctataaca
    83281 gatggtcaaa tatacttaca accagagtta ttctattcag gtgtaagacc agcagttgac
    83341 cctggtatat cagtatcaag ggttggtggt tctgcgcaaa ttaaagcaat gaaaaaagtt
    83401 gcaggaacat taaaacttgc atattcacaa tatagagaac ttgcagcatt ctcacagttt
    83461 ggttctgact tagatgaaga tactaaaaag agacttgctc aaggtgaaag aatcgttgag
    83521 atattaaaac aaggtgagca tcaaccaata aaagttgaaa atcaagttat gataatatat
    83581 gctgttataa ataatcattt agaggatatt ccgatagata atatagctag atttgaatca
    83641 gaattgtatg catttgtaga taataattat ccggaaatat caagaaaaat attaggtgga
    83701 gaagacttca ctcatgattt aacagatgca ataaatgaat ttaaagaaaa gtttgttgtt
    83761 gaagtataat cctttttaaa aaaggaggta aattaattgg caggagctgg aatcaaagca
    83821 atcaaaacac gtatgggaac tgttgaaagt acaaagcaaa taactaaagc aatggaatta
    83881 gttgcatctt ctaagcttag aaaagcaaaa gaaaaggctg aagattcaag agaatatttt
    83941 aatactttat acaatacagt aaaagatatt gcccaaacaa cacgtggaat tagaaatgaa
    84001 tttttaaaag aaagagaagt aaaaaataaa tgctatgtag tagtagctgg agacagagga
    84061 cttgcaggtg gatacaattc taatgtatta aaggaatctg tctctcatat gaaaggtaaa
    84121 aaggaaacag tgattactgt tggaaagaaa gcacatgaat ttttttctaa aagaaactac
    84181 aatatagcaa aagatataaa tagtgttgaa gcttgtggat atgaagatgc gacagaaatt
    84241 tcacaaacta ttattgacct gtataaaaaa ggtgaagtag atgaagttta tattgcttat
    84301 acaaaattta aatctgcttt atcacaagaa gttgaaattt tgaaattgct tccattagtc
    84361 tttgaaaaag atacagacga acaaggaatg gcagtaaaag aagaaaaaca aaatagatca
    84421 aaagtacaat atataccatc agcagaagca gttttaagtt atattgtacc tcagtttata
    84481 tcaggtacag tatatggtgg aattttggaa tcttttgcat cagagcaagg tgctagaaga
    84541 actgcaatgg aatcagccac agacaatgcg aatgaaatgc tatctaattt agagttaagt
    84601 tataacagag caagacagtc agctgtaact caagaaataa cagagatagt tggtggagtt
    84661 gaagctctaa aatagggagg ttaggaaatg gcaaatgtag gtaaagtagt acagattgta
    84721 ggagctgtac tagatgttaa gtttgatagt gaacaaagcc tacctaactt attaaatgcg
    84781 ttagtaataa agttaggaga taaagaaata gttgcagaag ttgctcaaca tataggtgat
    84841 gatactgtaa gatgtatagc tatgagtgca acagacggac ttgtaagagg tatggaagtt
    84901 gtagatacag gagggccaat aagtgttcct gttggagatg aaactttagg tagaatattc
    84961 aatgttcttg gaaaaccagt tgatgggaaa ccagctccaa aatctgcacc taaattacct
    85021 atacatagac cagcaccggc gtatgatgaa ctagaaacta cagcagagat actagaaact
    85081 ggtattaagg tagttgactt actagctcca tatctaaaag gtggaaaaat aggtctattt
    85141 ggaggagcag gagtaggaaa gacagttcta atacaagagc ttataaacaa tattgctaag
    85201 caacatggtg gtatttctgt attttcagga gtaggagaaa gaacaagaga aggtaacgac
    85261 ctttatggcg aaatgagtga gtctggagtt ataaataaaa cagctctagt atttggtcaa
    85321 atgaatgaac cacctggagc gagaatgaga gttgctttaa ctggacttac aatggcagaa
    85381 cattttagag atgagcaagg acaagacgtt ttacttttcg ttgataatat attccgtttc
    85441 acacaagctg gttcagaagt ttcagcactt ctaggacgta tgccatcagc tgttggttat
    85501 cagccaacat tagctactga aatgggtgca cttcaagaga gaataacatc aactaagaaa
    85561 ggttcaataa catctgttca agcagtatat gtaccagcag atgacttaac tgacccagca
    85621 ccagctacaa cattctctca cttagatgca aaaacagttt tatcaagaca aatatcatca
    85681 ctgggtatat atccagcagt tgaccctctt gaatctacat caaggattct tgaccctagt
    85741 atagtaggaa aagaacatta tgaagtagct agaggtgtgc aatcaatact tcaaagatat
    85801 aaagaacttc aagatataat tgctatactt ggtatggatg aattatctga tgaagataag
    85861 ttaatagttg cacgtgctag aaagatacaa agattcttat ctcaatcatt cacagttgct
    85921 gagcaattta caggaaatcc aggtcaatat gttcctgtta aagagactgt aagaggattt
    85981 aaagaaattc ttgaagggaa acatgatgac ttaccagagt cagcattctt atttgtagga
    86041 acaatagaag acgctgttag aaaagcgaag ggaagtatgt agtcatggcc agtgaatttt
    86101 cattgaaagt tgtaactcca agtaatactt tttatgatgg agatgttgaa atgatagtag
    86161 ttagaactac aaaaggagac aaaggggtgt tgaaaggtca tataccattt gtttcaggta
    86221 tacctgtagg aactttaaag ataaaaaaag agggaagttt taaagaggcg aaaatagcag
    86281 aaggattcat taatgtaact caagataaaa ctgtcatatt gacagaatct gctgagtgga
    86341 tttaataaat taatttagag tataaaaagt cattttgacc aaaaaaaact tttgggtaaa
    86401 atggcttttt tgcgttttgg tgttaataaa ataacgataa aattgtaagt ttttagtgat
    86461 aataaattca caaaatgttt aaatttactg ccaaattatg ttgtaattaa taagataaag
    86521 aagatttaga tagcttttat gtaagtgaaa aagtcttcat ataagaaata catataaaat
    86581 ttttataaaa tttaaaaaat ttgcttagtt gtgtagtata ataaataata taatagattt
    86641 gtatataata ttcattacaa ataattttaa aagttacagt tttattataa tgattattaa
    86701 attaagataa gtaacataaa ctaaataata atgtgtatta tcgatagtaa atttataaat
    86761 tcattattaa ttattgaaag aagtattata aattttctgg aggaacaatg aatatatttg
    86821 atattggcgt agatataatt gaaattgata gaataagaaa ggctgtagac aaaaataata
    86881 ggtttttgga gaagatattt acagatagag aaatagagta ttttaattct aagaatttta
    86941 aagcagaaag tatagcaggt aatttcgcag ccaaggaagc tataagtaaa tctataggta
    87001 caggaattag agtgtttaat tttaaagata tagaagttct cagaaatgaa atgggaaaac
    87061 caatagtaaa aacttataat aatctagcaa aaatgtgcat agattataat gttttagaaa
    87121 taaaagtttc aatatcacat tcaaaagatt atgctatagc aaatgcgata accataatta
    87181 aggactaagg agtgattaca ttatgatgga taaaacagca aaagaaataa tgacaacaga
    87241 tgtaatagta gcaaaacaag atgatagtat agcagatgta gctaatatgc taattgcaga
    87301 aaaaatagga ggtctgccag ttgtagattc agagaataga gttgttggaa taatttctga
    87361 aacagatatt cttaaaaaag aaaaatatat agaagcacct ctctatataa atctattaca
    87421 aggattgatt ttcttagatg acttaaaaaa agttgaaaaa gatataaaac aagtagctgc
    87481 ttataaggtt ggagaactta tgtctaaaga tataataaag gttcatgaag atgataagtt
    87541 tgatgatgta gctaatgtaa tgattaaaaa atcaataaac agagttcctg tagtagatga
    87601 tgacaacaaa cttaaaggta taatttgtag atatgatata ataaaagctt tatacaatga
    87661 ataaactgaa gtaggaggtg tgatgtgaga aaaaagtgga ccatagtatg tattatgttc
    87721 ttggcactgg ttataattgt aataggatgc caaaaacgac agtccacaaa agaagaagta
    87781 tacaaagatt ttcaaaagca gatttctgat atgaattatt acagttgtaa agctgaagta
    87841 gaagtagttg gaaataaaag tccacacaat tatgttttaa ttcatactta taaaaaaacc
    87901 gataactata aattagaagt aatttcccca aaacatttaa aagggaaaag tatagaatat
    87961 caaggtgata aaatattagt taaaaatcca aagattagtg atgtagtgga gttacctaat
    88021 acaggaaaaa ataatcaata tctttttgta ggagacttta taaaaaacta tcttcaaaat
    88081 gaggagatga aagtaaagtt atcgaaagga catttggttt tagagacttt tattcctggg
    88141 gataataaat attttaacaa gcaagtatta tatgtaaatg ctgacacaaa aaatcctgaa
    88201 aaaatggaag tgttagataa agagggagtg ccaagattta cagtaaaata caaagatttt
    88261 gaatacagaa actaaggggg actaaagaca tgcaaaaaat aacagtgcct acatgggcag
    88321 agataaatct agataactta agatttaact taaataatat taaaaattta ttagaagaag
    88381 atattaagat ttgtggagta ataaaagctg atgcatatgg acatggtgca gtagaagttg
    88441 caaaattgct agaaaaagaa aaagtagatt acttagcagt agcaagaact gctgaaggaa
    88501 ttgaacttag acaaaatggc ataacacttc ctattttgaa cttgggatat actccagacg
    88561 aagcttttga agattctata aaaaataaaa taactatgac agtttattct ttagaaacag
    88621 cacaaaagat aaatgaaatt gcaaaatctt taggagaaaa agcctgtgtt catgttaaaa
    88681 tagactcagg gatgactaga ataggtttcc aacctaatga ggagtcagta caggaaataa
    88741 tagaattaaa taaattagaa tatatagatt tagaaggtat gtttactcat tttgctacag
    88801 ctgatgaagt aagtaaagag tacacttata aacaagctaa taattataaa tttatgtctg
    88861 ataaattaga tgaggctggt gtaaaaatag ctataaaaca tgtatcaaac agtgcagcta
    88921 ttatggattg ccctgattta agattaaata tggtaagagc aggaataata ttatatggtc
    88981 attatccatc tgatgatgta tttaaagata gattagaatt aagaccagcc atgaaattaa
    89041 aatcaaaaat cggacatata aaacaagttg aaccaggtgt aggaataagt tatggactaa
    89101 aatacacaac tacaggtaaa gaaacaatag ctacagttcc aataggatac gcagatggat
    89161 ttactagaat ccaaaaaaat ccaaaggttc ttattaaggg agaagtgttt gatgtagttg
    89221 gtagaatatg tatggatcaa ataatggtta gaattgacaa agatatagac ataaaagttg
    89281 gagatgaggt tatactattt ggagaaggcg aagttacagc tgagcgtata gctaaagact
    89341 taggaactat aaactatgaa gtgttatgta tgatatcaag aagagttgac cgtgtttata
    89401 tggaaaataa tgagcttgta caaataaaca gttatttgct aaaataaaac catgatatta
    89461 taatctggga ggcgattttg tgtacgataa gagtaaagaa aaaatagaag ttactttacc
    89521 tgactctctg atttctgaag ttgatagtat agttcagatg gagaacagta acagagaaga
    89581 ttttgcaaaa gctgcttttc agttctatat aactcagaaa aagaaaattc atattaaaga
    89641 atctatgaaa acgggttata gagaaatggg tcaaattaat ctgtcactag ctgaattagg
    89701 tatgacagtt gaagaagtat cttctgatga taaaaatgaa gggaagattg cccaaggtga
    89761 gtactaattg tgaaataaag cgtggtgatt tatattacgc tgatttaagt ccagttgttg
    89821 gttcagagca gggaggcgtt agacctgttc tgataataca aaatgatgta ggtaataaat
    89881 atagtcctac agttatagta tcagctataa catctcagat taataaagcc aaattaccta
    89941 ctcatgtaga gataagttcc aatgaatatg ggcttaataa agactcagta attcttttag
    90001 agcaaattag aactatcgat aaaaagagac tgagggaaaa aattggttgt ctagatgaaa
    90061 atatgatgat aaaagtagat gatggacttc aaataagttt aggattgttt actttttaaa
    90121 gagggatttg tcttttatta gacaatccct tttttctttt aaatatctct taaggtttaa
    90181 ttttaatgta ctatgttaat aaaattaaaa ataacgcaaa aaaatagcat aaaagtgata
    90241 taataatatg gaattgatat aaaattacga actcaaggga ggtaattgca tgagagacca
    90301 taaaggatta aatgagattg cgcgtatcat aagaagagat atagtttcaa tgatacatag
    90361 agccaaatct ggacatccag gagggtcatt atcagtagtt gaaatactta ctgcgttata
    90421 ctttgatgaa atgaatgtgg attcttcaaa tcctaaaatg gaggatagag atagatttgt
    90481 attatcaaaa ggacatgctg caccagcatt atatgctaca ttggctgaaa aaggctattt
    90541 tgataaggaa gaactgaatg gattaaggaa gataggaagg atgttacaag gtcatccaga
    90601 catgaaaggc acgccaggtg tggaaatatc tactggttct ttaggtcaag gtttttcagt
    90661 tgcatgtggt atggctatgg catcaaagtt ggataatgct ccgtggaatg tgtatacttt
    90721 gcttggtgat ggtgaggttc aagaaggaat tgtttgggaa gctgctatga gtgctgcaca
    90781 ttataaactt gataatttaa ttgctttttt agataataat ggacttcaaa tagatggaga
    90841 tatagaaagc gtaatgagtt taggttcaat agttgataaa tttaaagctt ttggttggaa
    90901 tgtaattgag atagatggac atgattttga ccaaatattt gcggctcttg atatagctaa
    90961 atcaacagtt aaaaaaccta caatgatagt tgcaaaaact ataaaaggca aaggaatatc
    91021 ttttatggaa aatcaagcag gatggcatgg gacagctcca agtgatgagg agctagaaaa
    91081 agccttgctt gaattaggag gtgctgacaa tgagtaaaat ggcgacgaga gaagcatatg
    91141 gtaaagcatt agtaaaatta ggtcaaataa atgacaatgt tgtagtatta gatgcagatt
    91201 tatcaaagtc tacaaaaaca catgattttt acaagtcatt tccagataga ttttttaata
    91261 tgggtatagc tgaacaaaat ttaataggcg ctgcttgtgg attatcaact gctggtaaaa
    91321 taccttttgc aagtactttt gctatgtttg ctacgggaag ggcttttgag attataagaa
    91381 attcagtttg ttatccaaag ctaaatgtaa aaatatgtgc tactcatgca ggtcttactg
    91441 ttggagagga tggagcatct catgaaagtg tggaagatat tgctataatg agagctatcc
    91501 caaatatgac agttcttgtt ccagctgatg gagttgaaac agaaaaaatt atttttgaaa
    91561 tagctaagta taatggacct gtttatgtta gattagggag aagttcagta tcagttttat
    91621 ttgatgaaga ttataaattt gaaataggaa aaggtacagt cttaagagaa ggaaaggatg
    91681 tatcaattat agcttgtgga attatggtaa atgaagctct attagcacaa gaaaagttgc
    91741 aagaagaagg tataagtgct agagttataa acatgtcctc gataaaacct atagacaaag
    91801 atttaatatt agaatcagca aaagaaacga atgctattgt aactgtagaa gaacatagca
    91861 taattggggg attaggttct gctgtaagtg aggtagtagg agagtcttgt ccaaccattg
    91921 taaagaaagt tggaattaaa gatacatttg gagaatctgg tactccaaat gaattgttaa
    91981 aaaaatatga attaacttgt gatgacataa taaagactgt taaagaagct attattgcaa
    92041 aaagaatgta agagatataa attattcatg tttgttaata atataatata tttaaaagag
    92101 aggtataaag tgttatatta atttatatct ctcttttttt tatatgatat caatatatca
    92161 aaaatgtaat aaaatattca aatttttaca aaaatagaga aaatattcaa atatatattg
    92221 actattcaga aaaatatgac taatatataa tttatagaga aactaatttt atatataatg
    92281 actacttaga taaaagaatc taaaaaaatt atgagaggag gagtagggta taaaatcaga
    92341 ttataagttt taagttatta tactaaaaag ctataaaaca gttatcatgt attttatgtt
    92401 aaaggaaatt gtaggtagtt tatcgaattg tttaatcaga agaaaaaatt tcacatgggg
    92461 aggtaactga gatatgtcag aaaaagtaaa tgttaaaaca gtcatcagtt tcgcaggtgc
    92521 gtatgtagca acagtaatcg gttctggatt tgcaacagga caggaaataa tgcaattctt
    92581 ctctttttat ggttttgcag gtattattgg tgggataatt tcaatggtat tattctcatg
    92641 gatgggtgct tcagttatgt caaaaggtaa agagcttcaa cttaaagaac ctatcaaaat
    92701 ttatcgtgtt tattgtggta agtatttagg aatattcttt gaatggtttg gacctttatt
    92761 cttatttggt gttttcgtag taatgatttc aggagcagga gcaactttaa ctgaatacta
    92821 tggattaaat ccatttgtag gtagagtagg tatggcagta gtagcattat taactgtttc
    92881 actaggtctt gataaattat caaagatact aggtggaata gggcctataa taataatctt
    92941 tacactttta gttggtggta taagtttagc taaaaacata ggtaatatag gagaagctgc
    93001 acaagttctt agcactgtaa agatagctaa accagttcca aatgcctatc tatctggtgt
    93061 aatatatact acttataaca caattgttgt tatggcattc ttaactggat taggagcaag
    93121 tgctgctaac aaaaaagaag ctatttgtgg tggtatatta ggtggagtag cacttatggc
    93181 tgcagctata atgatgcact tagctattct ttctgatata ggaaacttat attcaaaagc
    93241 aataccatca ttattcttag cagataagat ttcaccagta attggagttt tattctcaat
    93301 aattcttata ttaggtatat atacaacagc tgtaccttta ttatggtcag taactaatag
    93361 atttgtagat gataaacatc ctaagtttaa attaataact ttaatagcag ctatattagg
    93421 tcttataggt ggcttcctac catttgataa gctggttggt attttatatc catatactgg
    93481 atatatgggc gtcataatac tggtttgtgt tctttataga cagattacaa aaacatctgg
    93541 atatcaagaa ggaatcagtg acaaataagt attttttaat attgtaaact caagagctat
    93601 atgaaaacaa tgaaaatgtt ttcatatagc tctttttatt ttttagctcg tttattatga
    93661 aatagaaaaa acatgttttt tagttacatt acatatattt ataattatgt ataaatatat
    93721 actaatcaat aatttagagt ctaagataag tttataaatc atatatttag aatatatggg
    93781 aggagtgata agattgaatg taaagtttaa tattaaaggt ataatttatg gagttatagc
    93841 tcttgtattc gttatagggg gatttatatt cataccaagt atgtttgtag agaaatctaa
    93901 acccatagat tatacagtat tacaaagaaa ttcaatacca gaaaagatat tagatgtgat
    93961 ggataagtat acaaatgaag aaagagcatt agcggctaaa atcgataaca aaatatacat
    94021 tatagtgact agaggaaata ataaatatgg tatagaaatg gacaaaatag aaagtgtggt
    94081 tgaggaagga aaggatgttt tgagagtcaa gataaagtat aaagataagg aagattcttt
    94141 tccatacata gttgttgaaa caaatatgag tgaacttcca gatagaatag aattaaatgc
    94201 gacgaaataa gaaggtattt tataattaaa taactgcata ttgtacaata aagtcatggt
    94261 ttttattaat gtaagtaaat tgtgtatggt tcttattgtt gtaaaagcca tgacttaaaa
    94321 tgcttataaa gtaagatatt aacagtagta tttattacta cattaaatgg ggtctggaaa
    94381 tacttaatat tctaactatt tggagtgata attctagttt cagtaactat gtagtctaat
    94441 tgtgcatcat gagtttcttt tggaatagaa tcgaatatct ggaagtcaaa tgctatgccg
    94501 atagttatag catcttttct taagttttct aaaaatctat cataaaatcc tccaccatat
    94561 cctaatctat agcaatgtat atcatatgct acagctggta caattacaac atctaaggcc
    94621 ttaatatcaa ttgtaggtga tttttcgtta ggttctctta ttccatatgc tccaattctc
    94681 aatccctctt ttaaatctgt tatttgagta gggattaatg tatgattttc ttttattgtg
    94741 atgggacttg atactatttt ctttagagac aaaagttttt tgattaaatt atctgtttga
    94801 acttcattgt taaaatttag ataaagcatt atattagttg catttcttat atcttccatt
    94861 tgaagtaatt tttcagttat taaatttgaa ttactaagta caaagtttgc actcttattt
    94921 tttcttgatt caataacttt ttttctaaat tcttttttca taaaataatt cctcccttaa
    94981 tatgttataa tgtgtacagc aattgtattt aatataaatt ttagtataat ttattgtaat
    95041 aaagcaatat atttgggtaa atgtaataaa aataacagct agtcatataa taataatagt
    95101 ttatgtaaaa ggagatgtat cttgtgattt caaagaagaa agctattttt ttaggggtga
    95161 ttttagtaat tataacagct atggttacat cagcatttca gttgacattg gggaataaag
    95221 ttgtaatatc gaaagaactc tatgaagact ataaaaaata tgataagttg ttaggactag
    95281 aatctattat aaaacaagat ttttataaaa aagtatcaga tactgatttg gtaaatggag
    95341 cagcaaaagg tctatttcta ggaacaaatg ataagtattc tggttattat actaaagatg
    95401 aaatggagaa tctaattaat gatagtgaag gttcttatgt tggtgtaggt atgtatatag
    95461 gggcatcaaa agatggtggc ttagtagtag ttcccatgaa agattctcca gcagagaaag
    95521 caggtgtaaa atcaggggat aaattagtaa aagtcaatgg aaaatctgtc tcatataaaa
    95581 attcagatga agctgttcgt atgatgaagg gtaaaaaagg taaaacagtt gaactgacta
    95641 tattaagaga agataaacaa ttgaacttta aagtaaaaac agaccagata attgagaaga
    95701 gtatagaaag taaagtaatt gataatgatt taggatatat agaaattacc caatttatat
    95761 caagtacata tactgacttt gataaagctt taaaagaatt aaaagcaaaa aatatcaagg
    95821 gattagtaat agaccttaga aataatcctg gtggaatgct agatatatgt aaagaagttg
    95881 ctgatgagtt aattggtgaa ggaaccatag tatatacaaa agataataag ggaaatactg
    95941 agtacttgaa atctgataaa gaaaaattgg gacttccaat agtagtgtta actaatggag
    96001 aaagtgcttc tgctgctgaa atattaacag ctgcaatcgt tgataataaa gaaggtattt
    96061 ctgtagggac tacaactttt ggtaaagggt tggtacaatc agttgtaaga ttgaaggatg
    96121 gaacaggata caagttaact actgctcaat attttacacc taatggagat tatatcaatg
    96181 aaaaaggtat aaagcctact attgaagaaa aagatgaaaa taaacagtta gatgtagcaa
    96241 ctaagtggct tagagaacag attgataaat aggatttaat ttttataaac ttatactata
    96301 aaataaagaa cattataaaa gagatgtctc aaaatgaact ttttagttca tgagggagtc
    96361 tggaaatatt tatgtgtatt ctttaaataa aaatttattt tttaagtgat aattaaattt
    96421 ttacagacag ggctatggtt ttaaaaatca tagccttatt ttgatatttt ttaaaaacac
    96481 attgcaaccc agttgttcca aatattatat catttacttt taaaatatcg taaactgcat
    96541 attatatatt cattataata taatttatct aactagaacc tcagtttact aattaaatta
    96601 gatgcataga ataacttttt taaacattga aaataaatta aactctaaac acatttaaat
    96661 ataaatttat at
//
LOCUS       DAGQVA010000005        85520 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.005, whole genome shotgun sequence.
ACCESSION   DAGQVA010000005 DAGQVA010000000
VERSION     DAGQVA010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 85520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85520
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.005"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            32..1144
                     /locus_tag="MIV85_000451"
     CDS             32..1144
                     /locus_tag="MIV85_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBY2959827.1"
                     /translation="MNSRVKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLAYLLLKKLNVGSTATIITFLCIATFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENL
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="MIV85_000452"
     CDS             1398..3422
                     /locus_tag="MIV85_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2959828.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHNTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRTNNYPAVLVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="MIV85_000453"
     CDS             3642..4328
                     /locus_tag="MIV85_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBY2959829.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="MIV85_000454"
     CDS             4423..5478
                     /locus_tag="MIV85_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBY2959830.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="MIV85_000455"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="MIV85_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBY2959831.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="MIV85_000456"
     CDS             7195..8901
                     /locus_tag="MIV85_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBY2959832.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="MIV85_000457"
     CDS             8923..9996
                     /locus_tag="MIV85_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBY2959833.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="MIV85_000458"
     CDS             10008..10730
                     /locus_tag="MIV85_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBY2959834.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LVCGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="MIV85_000459"
     CDS             10746..11903
                     /locus_tag="MIV85_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBY2959835.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRILLFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPVILTLFSVIIGTVFDKSTLLNRLLASRPKFWNVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="MIV85_000460"
     CDS             11906..12745
                     /locus_tag="MIV85_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBY2959836.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="MIV85_000461"
     CDS             12760..13935
                     /locus_tag="MIV85_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBY2959837.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="MIV85_000462"
     CDS             13964..14713
                     /locus_tag="MIV85_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBY2959838.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="MIV85_000463"
     CDS             14735..15643
                     /locus_tag="MIV85_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBY2959839.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="MIV85_000464"
     CDS             15691..16443
                     /locus_tag="MIV85_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBY2959840.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16397..17764
                     /locus_tag="MIV85_000465"
     CDS             16397..17764
                     /locus_tag="MIV85_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBY2959841.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17770..18861
                     /locus_tag="MIV85_000466"
     CDS             17770..18861
                     /locus_tag="MIV85_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBY2959842.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="MIV85_000467"
     CDS             18945..20858
                     /locus_tag="MIV85_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBY2959843.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKDIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="MIV85_000468"
     CDS             21057..21764
                     /locus_tag="MIV85_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBY2959844.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            22066..24177
                     /locus_tag="MIV85_000469"
     CDS             22066..24177
                     /locus_tag="MIV85_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBY2959845.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24375..25340)
                     /locus_tag="MIV85_000470"
     CDS             complement(24375..25340)
                     /locus_tag="MIV85_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBY2959846.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25625..26581)
                     /locus_tag="MIV85_000471"
     CDS             complement(25625..26581)
                     /locus_tag="MIV85_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBY2959847.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GHGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26949..27737
                     /locus_tag="MIV85_000472"
     CDS             26949..27737
                     /locus_tag="MIV85_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBY2959848.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27860..28330)
                     /locus_tag="MIV85_000473"
     CDS             complement(27860..28330)
                     /locus_tag="MIV85_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBY2959849.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28469..29113
                     /gene="uppS"
                     /locus_tag="MIV85_000474"
     CDS             28469..29113
                     /gene="uppS"
                     /locus_tag="MIV85_000474"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBY2959850.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29156..30061
                     /locus_tag="MIV85_000475"
     CDS             29156..30061
                     /locus_tag="MIV85_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2959851.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30376..31923
                     /locus_tag="MIV85_000476"
     CDS             30376..31923
                     /locus_tag="MIV85_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2959852.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31926..32324
                     /locus_tag="MIV85_000477"
     CDS             31926..32324
                     /locus_tag="MIV85_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBY2959853.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32364..34097
                     /locus_tag="MIV85_000478"
     CDS             32364..34097
                     /locus_tag="MIV85_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBY2959854.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34329..35540
                     /locus_tag="MIV85_000479"
     CDS             34329..35540
                     /locus_tag="MIV85_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBY2959855.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35733..35993
                     /locus_tag="MIV85_000480"
     CDS             35733..35993
                     /locus_tag="MIV85_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBY2959856.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36347..38059
                     /gene="ptsP"
                     /locus_tag="MIV85_000481"
     CDS             36347..38059
                     /gene="ptsP"
                     /locus_tag="MIV85_000481"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBY2959857.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            38382..39932
                     /locus_tag="MIV85_000482"
     CDS             38382..39932
                     /locus_tag="MIV85_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2959858.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            39958..42660
                     /locus_tag="MIV85_000483"
     CDS             39958..42660
                     /locus_tag="MIV85_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2959859.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNVYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDVKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSAQQIVHKQCANDILSCIENCGLDKKYISVEVTEKVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQITKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
     gene            complement(43166..43831)
                     /locus_tag="MIV85_000484"
     CDS             complement(43166..43831)
                     /locus_tag="MIV85_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959860.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            44175..45605
                     /locus_tag="MIV85_000485"
     CDS             44175..45605
                     /locus_tag="MIV85_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBY2959861.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            45973..46551
                     /locus_tag="MIV85_000486"
     CDS             45973..46551
                     /locus_tag="MIV85_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBY2959862.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            46581..46727
                     /locus_tag="MIV85_000487"
     CDS             46581..46727
                     /locus_tag="MIV85_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBY2959863.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            47032..48411
                     /gene="scfB"
                     /locus_tag="MIV85_000488"
     CDS             47032..48411
                     /gene="scfB"
                     /locus_tag="MIV85_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBY2959864.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            48440..48937
                     /locus_tag="MIV85_000489"
     CDS             48440..48937
                     /locus_tag="MIV85_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBY2959865.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            49235..50899
                     /locus_tag="MIV85_000490"
     CDS             49235..50899
                     /locus_tag="MIV85_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBY2959866.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            50912..53362
                     /gene="recJ"
                     /locus_tag="MIV85_000491"
     CDS             50912..53362
                     /gene="recJ"
                     /locus_tag="MIV85_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBY2959867.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDDSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            53375..53887
                     /locus_tag="MIV85_000492"
     CDS             53375..53887
                     /locus_tag="MIV85_000492"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBY2959868.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            53961..56168
                     /locus_tag="MIV85_000493"
     CDS             53961..56168
                     /locus_tag="MIV85_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBY2959869.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            56193..56642
                     /locus_tag="MIV85_000494"
     CDS             56193..56642
                     /locus_tag="MIV85_000494"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBY2959870.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            56657..57271
                     /locus_tag="MIV85_000495"
     CDS             56657..57271
                     /locus_tag="MIV85_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2959871.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            57362..58918
                     /locus_tag="MIV85_000496"
     CDS             57362..58918
                     /locus_tag="MIV85_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBY2959872.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            58908..60170
                     /locus_tag="MIV85_000497"
     CDS             58908..60170
                     /locus_tag="MIV85_000497"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBY2959873.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            60244..62031
                     /gene="aspS"
                     /locus_tag="MIV85_000498"
     CDS             60244..62031
                     /gene="aspS"
                     /locus_tag="MIV85_000498"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBY2959874.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMLTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            62490..63722
                     /locus_tag="MIV85_000499"
     CDS             62490..63722
                     /locus_tag="MIV85_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBY2959875.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            63736..64542
                     /locus_tag="MIV85_000500"
     CDS             63736..64542
                     /locus_tag="MIV85_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBY2959876.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(64654..65523)
                     /locus_tag="MIV85_000501"
     CDS             complement(64654..65523)
                     /locus_tag="MIV85_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2959877.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            65895..67322
                     /locus_tag="MIV85_000502"
     CDS             65895..67322
                     /locus_tag="MIV85_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBY2959878.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIGSVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(67399..67668)
                     /locus_tag="MIV85_000503"
     CDS             complement(67399..67668)
                     /locus_tag="MIV85_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959879.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMRGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(67671..69113)
                     /gene="nhaC"
                     /locus_tag="MIV85_000504"
     CDS             complement(67671..69113)
                     /gene="nhaC"
                     /locus_tag="MIV85_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBY2959880.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(69138..70304)
                     /locus_tag="MIV85_000505"
     CDS             complement(69138..70304)
                     /locus_tag="MIV85_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2959881.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKYYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(70529..72649)
                     /locus_tag="MIV85_000506"
     CDS             complement(70529..72649)
                     /locus_tag="MIV85_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2959882.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSNNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            72882..73283
                     /locus_tag="MIV85_000507"
     CDS             72882..73283
                     /locus_tag="MIV85_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959883.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQIGK"
     gene            73326..73619
                     /locus_tag="MIV85_000508"
     CDS             73326..73619
                     /locus_tag="MIV85_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBY2959884.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            73634..74074
                     /locus_tag="MIV85_000509"
     CDS             73634..74074
                     /locus_tag="MIV85_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBY2959885.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(74166..74639)
                     /locus_tag="MIV85_000510"
     CDS             complement(74166..74639)
                     /locus_tag="MIV85_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBY2959886.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(74639..75427)
                     /locus_tag="MIV85_000511"
     CDS             complement(74639..75427)
                     /locus_tag="MIV85_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBY2959887.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            75755..76999
                     /locus_tag="MIV85_000512"
     CDS             75755..76999
                     /locus_tag="MIV85_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBY2959888.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            77322..78419
                     /locus_tag="MIV85_000513"
     CDS             77322..78419
                     /locus_tag="MIV85_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBY2959889.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            78410..79108
                     /locus_tag="MIV85_000514"
     CDS             78410..79108
                     /locus_tag="MIV85_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBY2959890.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            79111..80175
                     /locus_tag="MIV85_000515"
     CDS             79111..80175
                     /locus_tag="MIV85_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBY2959891.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITSMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            80358..81062
                     /locus_tag="MIV85_000516"
     CDS             80358..81062
                     /locus_tag="MIV85_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2959892.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            81055..82377
                     /locus_tag="MIV85_000517"
     CDS             81055..82377
                     /locus_tag="MIV85_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2959893.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            82564..83937
                     /locus_tag="MIV85_000518"
     CDS             82564..83937
                     /locus_tag="MIV85_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959894.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEAFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(84309..85247)
                     /gene="pdaA"
                     /locus_tag="MIV85_000519"
     CDS             complement(84309..85247)
                     /gene="pdaA"
                     /locus_tag="MIV85_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBY2959895.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        33519 a         9267 c        14750 g        27984 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tataaatagt agagttaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagcat atttactgct
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tagctacatt
      481 tataatagtt gggtactaca tcttagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa aggacatttg tacaagccgg aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa acctaggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cccattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatataca gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaat gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aaaacttatg
     2701 tttctgcata ccataataca aatttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaccaat aattatccag
     3301 cagtacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaatagaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagaatt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaaaaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agagtttatt gcagagattg attctaactt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag tagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattggtct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaatgt atggatactg ccagcaggag cattattggc tatggcgagt
     6181 cagctattgt ttcaactgcc atttgcgttt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtctat aaaagagtta gtcaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gaccgattat tggcaaccac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagcac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttagaatatt attccaaagg
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacac caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atcaaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagatttta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaagc aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ctattaaaag tatagatttt gaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaaaca agttttaaga
     7861 caaaatataa tagatgaata cgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gttttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaggct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagcaatga tagaagtttt
     8401 ataatgggat atgaggaaag ctatggttac ttaattggaa ctcatgctag agataaggat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatggtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa caatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaacg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tactatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcaacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctagtct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtatt atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgatccaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcggca tgttttttaa
    11101 tggtagctat attattattt aatttatttc cttcattaat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaatacttt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccgg
    11461 taatacttac tttatttagt gtaattattg gtacagtatt tgataaaagc actttattaa
    11521 atagattatt agcaagtaga cctaagttct ggaatgtata cttggctgaa aaggggaact
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggacag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagact atacaagatt tgatgaaaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaagaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cggatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agccgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagcaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgtagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagag tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaagtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggttca gccaacctag attatataaa ggcagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagaacttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagacact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatacgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgactct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatctcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggaagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aaacataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagtgtgt atatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttgtgg caactttagc ttatttaatt ccgatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggcgcaagaa tagcctatag agctataaga atagtcatga
    19381 acaagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taaaaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca taatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agtacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag atattattga tatatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaaac
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcctaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgtaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt gaagacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gttatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtgcttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttgta tgaagaacta cttatgtcag
    20641 aagaaggtct attggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtaccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tataaatggg gagcaactgg accaaattct tttgattgtt
    21481 ctgggttcac ttcttatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaaa aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg ttttttttat aataaattat ttcatattat aatcaaatat caaatataaa
    21961 ttttaactat attattcaat atttgacaga taatatgaat tttagatata cttaataaga
    22021 agtatattgt agaaaaaata aatttaaaaa attaaggggg atgaaatgaa aaaaataagt
    22081 atattagtat tatcattgat aatgacactt actatgtgta gtgtaagttc atttgctgat
    22141 tcatcaaatg ataaggaaat gagagctgct tggatatcta cagtttataa tttagactgg
    22201 cctaagacta agaataatga agccaagcaa aaaaaggaat acacagattt attggacaaa
    22261 ttaaaaagtg taggaataaa tacagcagtg gttcaagtaa gaccaaaatc agatgcttta
    22321 tataaatcaa atataaaccc atggtctgaa tatcttaccg gtacacaagg taaagaccct
    22381 ggatatgacc cattaccatt tttaatagaa gaagcacata aaagaggaat ggaatttcat
    22441 gcatggttta atccatatag aataactatg gcagatgaga gcatagataa attgccagca
    22501 aaccatccag caaagaaaaa tccaagctgg gtagttaaac atggaaataa gtattactac
    22561 gacccaggtt taccagaagt tagaaagtac atagtggata gtatagcaga agtagttcaa
    22621 aattacgata tagatggagt tcattttgat gattacttct atccaggagt aagtttcaat
    22681 gatactgcaa cataccaaaa atatggaaaa ggacaaaata aggatgattg gagaagagaa
    22741 aatgtaaata ctctacttag agatgtaaaa gcgtctataa agagtataaa gcctaatgtt
    22801 gtatttggtg taagcccagc aggtatatgg agaaataaga gtagtgaccc aacaggttca
    22861 gatacatcag gtaatgaaag ttatgtaggt acatatgcag atacaagagc atggataaaa
    22921 caaggattga ttgactatgt agttccacaa ctttactggc caattggtct taaagcagca
    22981 gattattcta aattagtggc atggtgggct aatgaagtaa aaggaacaaa tgtagactta
    23041 tacataggac aaggtatata taagcaaggt caatcgagtt atggtggaca aaatatagca
    23101 aaagaaatag tacaacaagt aacattaaat agaaagtata gtgaaataaa aggtagtatg
    23161 tatttctcag ctaaagatat agcaaatagt acttctatac aaaaggattt aaagagttta
    23221 tattctagta gtgaagaacc agttactcca ccatctaatg ttaaagtgga gaaattaaga
    23281 ggcgacgaaa gatatgacac agcagtagca ataagtaaaa aaggttgggc tacaaattca
    23341 gatacagtag tattagtaaa tgggtactct atagttgatg gtataacatc aacaccactt
    23401 gctacatcaa atgatgctcc tatactattg gtaaataagg ataatatacc tacatccact
    23461 aagaatgagt taaaaagact taatccaagt aaagttattt taattggagg aaataactct
    23521 attggagata aagttgagag tgagataaaa gatacattgt caaatgtatc aataaataga
    23581 gttggtggtt cagatagata tagtacatct ttaatgatag caaaagaatt agtaaaaact
    23641 aatccagtag aaaaactata tataacaagt ggtacaggtg aagcagattc tctttctata
    23701 gcttcaaaag caggagaaga aaagcaacca atagtattag tatcaaaaga taatgtaagt
    23761 gatgaagttt acaattggat atcagattta aaagtaaaag atgcttattt tataggtggt
    23821 aatctaagta tatctgattc agtaataaat aagctggata aggtcattac aaatgatgta
    23881 tctaaaaata gaatagctgg agaaaataga gaagaaacaa atggaaaagt aatacaaaaa
    23941 ttctatccaa atgctgaata ttcatcaatg tttgtaagta aaagtaatca attggtagat
    24001 gcattaacat caggtccttt agcagctaaa ttaaaatcac cagtagttat gcttggaaat
    24061 agtgtaacat ctgctcagaa aactgcttta gagcctaaga aaactactct agtatacgaa
    24121 gctggagatg gtataaatca aaacacatta aacactttct taaacttagt taagtaataa
    24181 aaaagttaat ttaaaataca gagtatttta taaatgtaga ttaaaatgaa aattatcatg
    24241 ataaattaga aaataaaaaa gaactatatg cattttgtaa tcaagtgtac acagcaactt
    24301 gaaaataatt atgcgatata gttctttttt agtaattaat cttatacttt ttaataaact
    24361 ttatgttgaa ttttttattg tttaaactct atgtcattaa atataaaatc gtgtaatatg
    24421 tctaaagtat ctgggtcaaa tctaagaacc catccagctt ttccatatat accacctgta
    24481 ctatgaattt catcatcaat aggaaattca aattgcttaa tatttaagtc gcccattttt
    24541 aaaacttgag ctcctaaaga aagtattgca ttaggcttca tgttagtttt aacatatgga
    24601 agaactgcat ctaataaacc tggatattta gtaacaggta aagtttccgt tttcttgatt
    24661 atagcttgta taatctgtct ctgtctgcca tctctagcaa aggctgtatc gttgtgtctg
    24721 atacgtgcaa aagatagtgc ctgatatcca tttagagtct gctttccaga gtttctaatg
    24781 tattgtatgc tacctttatc atcactttta ttccatttat aagtttcagg aataaattta
    24841 tttagttctc gtatttctcc tttttcaaca gtaacctcaa cgccaccaat agcatcaatt
    24901 atatacataa atgattcgaa attaacacaa gcataatttt gaatatcaat attaaaattc
    24961 tcttcaattg tttgtattaa taaatcagct tgtccataag cataagcatg agtaagtttt
    25021 tgtttaccat gaccagggat gtctacatag ctatcacgag ctaatgatgt aagtttgata
    25081 tcattgtgtt tgttatcaat agtaagtatc atcatagcat ctgaccttga agaatcttca
    25141 tttggtctag catctgttcc cataagtagt atgttaatta tcccatcttc atttttatgg
    25201 tcattgttat ccaataaatc actacttatg ctcgagtcat gaatagcaga taatttataa
    25261 taaaaatatc catagacact tatagggaat attactacca agaaagccag tagtataaca
    25321 aatttcttta attttgacaa aagtacccct tctttcttct ttttcctgta tattttttaa
    25381 tagcatacac ttaattatat taaagtattg agatatattc aatacttgtt tcagttacaa
    25441 aaaaaagaca atgatataat ttataagaaa atttatcgac ctatatatat agttaaaagt
    25501 atatataata tattttttaa aagtaattta tattttaaaa taaaaacaca ccccataaat
    25561 acaaagtaat ttgcatttaa gaggtatgta tttatcatca aattattggt ttgttttgga
    25621 atttctaatc ttcaaccata atatctttaa atatgaaatc atgcattgca tctagttcat
    25681 attcctcaaa aggtattaca tagcctgcat tacctatttt tctaccattt tcagtagaaa
    25741 gaggaaactc catagatttc aaatttaaat ttcctatact taaaagttct tttcctaaag
    25801 atattatttc attaggattc atattagttt ttacatacgg aagtattgtg ttaactagat
    25861 taggatattt agtgactggt aaatccttaa caccatttat taaactctgt ataacacttc
    25921 tttgtcttct atctctttca tctgtactat cattttttct tatacgagaa aatgcaagtg
    25981 tctgatatcc atttaatttt tgctcaccag aatttcttat atatttaaga gaacctttat
    26041 tgtcattttt attccattta taagtttcag gaataaattt atttaattct cttatttcac
    26101 tcttatcaac agtaacagta actccaccta aagcatcaac tatatccata aaagagaaaa
    26161 agtcaactac ggcgtagttt tgtatatcaa gttggaagtt ttcttctata gtttctatta
    26221 ataagttagc ttgtccatat acgtaggcat gtgttaattt ttgttctcca tgtcctggta
    26281 tattaacata agtatctcta tttaatgaag ttagcttaag acttttattt ttattatcaa
    26341 tagtaagtat catcatggca tcagaacgag aaacttcttc tcctggtctt gcatctgtac
    26401 ctaacaataa tatgtttgtg atattttctt cgtttttata gtcattacta ctaagcgcct
    26461 ctgtatttat actatcatct tgtatagttt ttaatttagt aaaaacatat ccatatatac
    26521 taacaggaaa tgctataact aaaagggcta gaaatataac gaactttttg agtcctgaca
    26581 ataatatccc ctactttcta aattttttaa ttacacatag ttaattatat taaaaatttg
    26641 ttacataagc aataaaaaac acaataaatt agcataagtt tgtcataata taattatttt
    26701 tatagcattt tatagaagaa agtgtgtagt tattattgat tttattggaa tataattgta
    26761 tgaagactta aatttttata aactaatgtg tatattgaaa aaaatatttt cctgaatgta
    26821 gttatagcat cttatgaaag gtgcaaattg taatttaaaa tttttagtgt ataataagaa
    26881 ttgaaaattc aaaccgataa aaattaataa aaaataatta taaattaata atttggggga
    26941 ggaaatgtat gataaaatta atagcaacag atttagatgg aactttgtta gatgaaaaga
    27001 gcgaaataaa tccagagttt tataaagtat ttaaaaaatt aagagagaga gggataatgt
    27061 tttctgctgc tagtggcagg cagtatcaaa atctgataaa aaaatttgaa gatataaaag
    27121 atgatatgat gtttatatca gaaaatggaa cactagtagt atataaagga aaagaaatat
    27181 tatcaaatcc tttaaataaa gaattagtaa atgaaatcat agagacaaca agaagtataa
    27241 aagggaaaaa aattgtaatg agtgggaaaa aatacgctta tatagaaagc aaagatgaag
    27301 cgtttataca agaggttagt acttattatg caaagtttaa aattgtagaa gatttgacga
    27361 aagtagaggg agacatattg aagatagctg tgtttgactt caaaggtgca gaacataata
    27421 ataatatcta ctttgaaaag ttttctgata gagctcaagt atgtatttct ggagtggagt
    27481 ggcttgattt aactgcaaaa ggtgcaaata aagggagtgc cataaaaaaa gtacaaaaaa
    27541 tgttagatat aaaatatgaa gaaactatgg tatttggtga ccagttaaat gatgtggaaa
    27601 tgatgaaaag tgcctatcat agttatgcca tggaaaatgc aaatgaacat ttgaaacaaa
    27661 ttgctagatt tagagcaaaa agaaatactg aaaatggcgt tgtagataag ataaaagagg
    27721 ttataaaaat tggatagtca tatgtataga tgaaaaagat tattttgaag aaatcaaaaa
    27781 aatatcaatg taattttgat aaataagttt atttatgcga aaattacatt gatatttaat
    27841 aaacatcaat aatagatatt tattttttta tgatattcag tattttgttt tctatttgag
    27901 ttgcattttc agcagaaatt aaataaacat acctacctgc cttctcaatt atagtattat
    27961 ttgctatttc agaattgatt ttttctccat gtccttctcc aaaaggtgct tgtatcatat
    28021 cttttttata attttctaga gttttataga ttttatctac ctcgtcagtt tttataacga
    28081 taatatcttc tagagataat ttttcagaag aattaattac aaaaccttga attatgtctt
    28141 cctctacatc attaaaatag ttaaaatcct ttgcatcaaa gatttttgat tcctttataa
    28201 gtaaatcaga agattttaat gcttttttta tttttgatgt agaaacgttt ttgtaatcac
    28261 cacttgaaga acaactaacc attcctaatg ataagattat cgaaaaaaac aatattaaaa
    28321 tttttttcat gataaacctc caagtttttt aaactctgtc ttaaattagt ttactacata
    28381 attatataaa aataaatgta tttaatgtta cagttttgat taataatgta atattttgat
    28441 aataatacct attgagaggt gattagaaat gagaatacca aaacatgtag gaattatacc
    28501 ggatggaaat agaaggtggg caagtcaaaa tggtatgaca aaagataaag gatatgaaag
    28561 tggaatagac cctggactag agtcttatag attatgtaga gatttaggct gtgaagaggt
    28621 gactttttat ggatttacaa ctgataatac aagacgtcca tcagtgcaga caaaagcttt
    28681 tacaaaagca tgtattgatg ctgcaaatat attaatagat gaaggtgctg ctttattagt
    28741 tgtaggaaat acaaaatcgc caatgtttcc agaagaatta ttaccatata ctaatagaat
    28801 taaagccaaa gaaggtcaaa taaaagcaaa tcttctggta aattatggtt ggtattggga
    28861 cttaaataat atatcaggag tagaaaatgt aaataaaaat aatatacagg attacataca
    28921 gtcatttgat gtatccagac tagacttgat aatcagatgg ggtggaagaa ggagattaag
    28981 tggtttcctt cctgtacaat caatttatgc agatttttat gttatagata attattggcc
    29041 agattttaag agtgacgata taaaggacgc atttagttgg tatgatacac aagatgtcac
    29101 tttaggtgga taattaaaaa tattctgatt taaggttgta gagtgtttta aattattgaa
    29161 aaaaaaactt cttgatggta aaataacact aataatatgt aaaagtgtaa aaatttatac
    29221 caagaagggt gaagaaatgt caaaaggcaa taataacaat aattcaagaa acaaatctaa
    29281 aaagaccagt catctgaata gaaaaaagcg aaaattaaat aagaaaaagt tagcagtgtt
    29341 gatttgcttt acagttttat ttttatttat tgcatttaag gctactcaag gtgtagtagc
    29401 tttggtaaaa agtatggata aaagtaataa aactagtcaa caacaaaatg ttaactcaga
    29461 acaatttgac cttggtaatg aagaggaaaa taaaaagaaa aaatatactg tatttataga
    29521 cccaggtcat ggaggcaatg ataaaggaac tgaaagcaag accagtaata gatatgaaaa
    29581 agacctaaat ctacaaattg caaaaaaatt agcaaataaa ttatctaaac aaaaggatat
    29641 tcaagtagta gtatccagaa ctgatgatac atatatatca ttaaaggata gagctatctt
    29701 agcaaataat agttctgctg atgtgcttgt ttctattcat ttaaatgcag agaaaaatgg
    29761 taatacagca acaggtatag aaacttggta taggaataaa gctacagatg gttcaaaaga
    29821 acttgcacag acagtacaaa gtactatagt atcctatgtt aaagttagag ataggggaat
    29881 agttgaaaat aactttgaag tacttagaga atcaaatatg cctgctatat taatagagtg
    29941 tggtttttta acaacacctt cagaggaaca aaaaataata aatgaaaaat atcaagacca
    30001 acttgcggaa ggaattgttc aaggtgtact ttcataccta gattctaaag ggaataagta
    30061 aattaacttt actttaatgt gaggataaat ttaaaagttt aactgtgtaa attgtattaa
    30121 ctttatttcg taatgttgga aatattgttt gaatttagaa actatgaaat tagaaattat
    30181 tttatctata tctaatttca tagttttttt tgcaaaaaat ttatagttat aaaattttaa
    30241 aaaataaatt tagtataatg taatgtagtt atttatatgt gattttaact tgcattgatt
    30301 tgctatcaat tgtgctttat aattagtata tataaagttt aactgtaaga taatttaaaa
    30361 aataggggaa tttatatgaa taaaaatagc atgacaagaa tttacagttt aaataaaata
    30421 atttttatta taattggaat tttaggaata gttttactca caagacatat tgaggtagat
    30481 attaaagttt taattttaat tttattaacc ttgtttagta taaatgtatt tatttcatat
    30541 cttaaaatta agttgtatga ggataaaatt aatttaggat tgataaataa ttcagataag
    30601 tttataaata ttactaaaga tgagaacttc ctaaaacatg ttcaaaatta tattatcagt
    30661 aatgaaaaag aaaactgtgt aatggcttgt tttgatttat gtagactcaa acttataaat
    30721 gatatatatg gttatgagct aggggatgaa gtgttaaata atattttaag taacttaaaa
    30781 aattattttg gaaaagaagc tatttatgga aagttaaaaa gtgatgtttt tgtattaata
    30841 ataaagcttg aaaataggga acagaagatt ccttatttag taaatcttat taagaataaa
    30901 attgtgatac taagtcagat tgacagtttt aaaatggata taaatattga ggcttctatt
    30961 ggaatttata aatttaacaa taatgaaatt gatataaaaa aagctataga taatgctgat
    31021 atggcaaggc ttaaatcaaa aggactaaag cacatagagt atgtagaatt tgataatgct
    31081 atggaagaag aaatacaatc aattatgaaa atagagagag atttattctt ggctattaaa
    31141 aataaagagt ttgtaattca ctatcaacct aaagttgatt caagtacagg taacattata
    31201 ggttcagagg cattgataag atggttgcac ccatcattag gcatggttgg accaaataag
    31261 tttataccta tagctgaaaa aaatggtctg ataaacaata ttggtagatg gctaattcaa
    31321 gaagttttta ttaccattaa caagtggatt tcagaaggta taaatgtctt accagtctca
    31381 ataaatcttt ctagagtaga actatataaa aatgatttag ttgatttttt taaactgatg
    31441 tttaatacat ataatattcc aaaagaactt atagaattag aaattacaga aacgacagca
    31501 ctaagagatg taaaatttat aagtgaaagg ctttatgaga ttaaatcttt aggtatgaat
    31561 atatcattag atgattttgg agtaggtaat tcaaatttta tcaaccttaa ggggatacca
    31621 ctagatatta taaaaattga taggtcactt atattggata tagttacaaa tacaaaaaca
    31681 aagtttatgg tgaaagcaat tgttaacctt tcacatgatt taaacgtaac tgttatatgt
    31741 gaaggggtag aggatatgca tcaggtcaaa gtcttaagtg aactgggatg taatttcata
    31801 caaggttatg tattttttaa acctttggat gagatgaatt ataaaaaact tcttactgac
    31861 ggaagttata taaatctgaa agatactctt ttagataaat gcatgacagt tgaggaggag
    31921 taaggatgat ttcagaagat gtagattatt caataagaat cataagagct atatttaata
    31981 atggagaaga taaaccaata gatgctaaaa tgatattaaa aagtgaagat ataccaatac
    32041 taacactata cagactgctt agaaagcttt gtgcaaacaa tattcttact tttaacaaag
    32101 aagatggcaa gacatacatg ttaaatgtgt cattggatac aataagtcta agaactattg
    32161 tagaagtaat tgatggaaaa atatatataa ataaatgtac gagatatgta tctaattgca
    32221 gtaattgctt aaaaggttgt aaagtaaatc gtgaattgct agaaatagaa aaagaaattt
    32281 ataaactttt atcgagaaaa tctataagac aaatactaga ataaaaaatt ttcagctatg
    32341 ataataattg gaggttttcg gttatggatg atatatctca agataatttt ctactgtcta
    32401 aagagtatga gaatagctta gatgtagata ctaaaaaagc aagtggaata tattatactc
    32461 ctaaaataat tgtagattat attgtgaaaa aaactttaaa aaatcacgat ataattaaaa
    32521 atccatatcc acgaatactt gatatttcct gtgggtgtgg aaattttctt ttagaagtat
    32581 atgatatttt atatgactta tttgaggaaa atatatatga attgaaaaag aagtatgatg
    32641 aaaattattg gactgttgat aacatacacc gtcatatatt aaactattgt atatatggtg
    32701 ctgatattga tgaaaaagct ataagtatat taaaagatag cttaacaaat aaaaaggtag
    32761 taaatgattt agatgaatct gatataaaga ttaatctatt ttgttgtgat agtcttaaaa
    32821 agaaatggcg atataagttt gattacatag tgggtaatcc accctatatt ggtcataaaa
    32881 aacttgaaaa gaaatataaa aaatttctcc tagaaaaata tagtgaagtt tataaggata
    32941 aagctgactt atatttttgt ttttataaaa agattataga tattttaaag caaggaggga
    33001 ttggcagtgt tataactcca agatattttt tagaaagtct atcaggtaaa gatttaagag
    33061 aatatattaa atcaaatgtc aatgttcaag aaatagtgga ttttttaggt gcaaatatat
    33121 ttaaaaatat aggggtatct agttgtattc taacttttga taagaaaaaa acaaaagaga
    33181 catatataga tgtatttaaa atcaaaaatg aggatatatg tataaataaa tttgaaacat
    33241 tggaagaact tctaaagagt agcaaatttg aacattttaa tataaatcag agattgctat
    33301 ctgacgaatg gatacttgta aataaagatg atgaaacttt ttataataag atacaagaaa
    33361 aatgtaaata tagcttggaa gatatagcaa taagttttca aggaataatt acagggtgtg
    33421 ataaagcgtt tattttaagt aaagatgatg taaagttgaa ccttgtagat gataaatttt
    33481 taaaatgttg gataaaaagt aagaatataa ataaatatat agtagataaa agtgaatata
    33541 ggctaatata ctcaaatgat atagataatg agaatacaaa taaaaggata ctagatgaaa
    33601 ttatagggct atataaaaca aaattagaaa acagaagaga atgtaaaagt ggaataagga
    33661 aatggtatga acttcaatgg ggtagagaaa agcttttctt tgaaagaaaa aagataatgt
    33721 atccttataa atcaaatgaa aatagatttg ctatagatta tgataataat ttttcaagtg
    33781 cagacgtata ttcttttttt ataaaagaag agtatttaga taaattttca tatgaatatc
    33841 tagttggaat tttaaattcc agtgtttatg ataaatactt taaaataact gctaaaaaaa
    33901 tgagtaaaaa tatatatgat tactatccta ataaggttat gaagataagg atttttaggg
    33961 ataataatta tgaagagata gagaatttat caaagcaaat aatatcaatt ttattaaata
    34021 agtctataga taaaggaaaa gtagaaaaat tgcagataaa aatggataac ttgataatgg
    34081 attctttagg tatataagca gttgtaagta ttaaaaaatt ataatctttt aattgtttat
    34141 ttaaatttag aaataaaaag ttagccatat aaaaaatatt aaaaatatat acttttcaat
    34201 atttttttga taaaataaga atgaatttgt gcaattttat ttttctccaa taactaaaaa
    34261 tagttttttg aattaatatt tgcttaagaa taaaaatcag aaacgttttt gatatagtag
    34321 gtgataatat gaaaggatta gttttagaag gtggaggaac aaaaggagcc taccaaatag
    34381 gtgcatataa agctttaaga gagcttggta tagagtttca aggagtaact ggcacatcaa
    34441 ttggtgcttt aaatggagca tatataattc aaaatgatat tgaagtaatg gaagatattt
    34501 ggttaaatta tgactatact cattttatga atattgatag agaaacctat gagaggttta
    34561 aaaatgtaga tttcactact aaaaatctca atgcagtgtt tgagcttata aataaagcta
    34621 gaaaaaatga aggtatagat ataagcccat taagacaatt aatggagaca acattaaatg
    34681 aagacataat aaggaaatca aaaaaagact ttggacttgt tacggtctgg tgggataaaa
    34741 aaattaatcc atatccattg tatatcgaag atatacctaa aggaagattg attgattatt
    34801 taattgctag ttccagtttg cctatttttc aaacgaacat gatggatgat aagttgtatc
    34861 ttgatggaat gttttgtgat aacatgccaa taggactctt ggaagacaaa ggttatgaag
    34921 atgttgttgt aattaggttg attgatgatt ttattgggaa aatgaatcta aatcgacatc
    34981 aaaatataaa tataaaaact ataataccat cagaatatct aggaggttct cttaataaag
    35041 atagagataa tgtagaaaaa aacatccgac taggttactt agatactatg aaagcatatg
    35101 aaagatgcac tggaattaag tattattttg atgtagagta taaatataat gaagaatatt
    35161 gttttgataa atttagaagt atgagcaatg aaacaataca atatatctgt aatttattga
    35221 atataaaaag agatgcttca cttagaactg ttatggaaag tgtaatacca aagcttggtg
    35281 aggtgcttgg attgccaaag gatttttcat ataaagattt gttttactgt atatatgaaa
    35341 agaaacttga agaaaataat ataaacagga taaaattata tgattttaac aaggttatag
    35401 atgttgtaaa tacaaatatt gattctaata gaaatttagc ttctaatttt gaagttagac
    35461 ctaaaattag tattaaaaag aacaaaaaca caaaattatt gacaaattgt attataaaag
    35521 acataaaaaa tcaaagttaa ataaaaaaca aaaaaaaatt tgtaattata ctcgaaaaaa
    35581 gtgtatatta gtagtataat atttttgtag cactagtggg aacaaaaaat gaccatagga
    35641 caaaaaagta ccacttagta ccattaaagt aaaaaacagg aaaacaattt taaaaaatat
    35701 aaaatgtaaa gtttatagga ggatttaaaa aaatggaaaa agtagttagt atcaaaaatg
    35761 caagtggatt acatgctaga ccagcaggaa tgtttgttaa gaaggcagct gaatttaaat
    35821 caacagtaga ggttgtagca aaagacaaaa ctgtaaatgc aaaatcaata atgggaataa
    35881 tgagtttagg tttagctcaa ggagaagaat taaagttagt tgtaaatgga gaagatgaag
    35941 aagtagcttt agctgcaatg gttgaattag ttgaaagtgg atttggagaa tagatataat
    36001 aattttttaa aaatttgata tttagaatct aatattactt aaagtaaagt aacagagaag
    36061 tattaaacat atacagacca acatttgtag atatttaatt tctttgttac tttcatgttt
    36121 atttaatcag aagattaaga ctattgttaa ttgggtataa aaatataaat attttagaaa
    36181 atgaaataag atatttttaa tcataaattc agagtaaaaa tacagtaaca aatagtttat
    36241 aaaattttat aaaaaattat aagtaaataa aactataaaa atgtaaatta tttatataaa
    36301 tttataaagt ttatgtgcta gatgatattt tttaggaggt agagttatgg cttacaaagg
    36361 aataggtgct tctcctggtg ttgctttagg gaaagcgtta gtagttgaac atagtgaatt
    36421 agtaattgaa aaaaaatcta tagataatgt tgaagctgaa attgctaaat tagaagatgc
    36481 agttgcagtt tctaaagaag aattagtaaa agttaaggaa aaggcttctg aagaattagg
    36541 agcagaggaa gcagaaatat ttgaagcaca tttattagtt ttagaagacc cagagttaat
    36601 tggttctgca atagataaaa ttaaaactga aagtgtaaat gcagagtatg ctttaaatga
    36661 aataaaagag atgtttgtta gcatgtttga gtctatggac aatgagtaca tgaaagaaag
    36721 agcggcagat ataaaagatg ttacaaatag aatacttaga catatattag gaattaaagt
    36781 tgttgattta tctgctttaa gcgaagaagt tgtattaata gcacatgatt taactccatc
    36841 agacacagca actatgaata aaaaaatggt tttaggattt ttaactgata taggtggaag
    36901 aacttctcat actgctatca tgtctagaac tttagaaata gctgcaatcg ttggattaaa
    36961 tgatataact tcaaaagtta aggatggaga ttttgtggtt ttcaatggag acacaggtga
    37021 agtaatcgtg aatcctgatg aagagactat aaataaatat actgaattaa aagctaagta
    37081 tgaagatgag agaaaagcat tacagctatt aaaaggaaaa ccatctgtaa ctttagacgg
    37141 aaaacatgtg gaattagctg gtaatatagg aacacctaac gatatagaag gtctaataaa
    37201 gaatgatgct gaaggtgttg gtctttatag aacagaattt ttatacatgg atagagattc
    37261 tttcccaaca gaagaaatac aatatgaagc atacaaagct gtattagaag gaatggatgg
    37321 aaagcctata gttataagaa cattggatat aggtggagat aaagaattaa gttatttaag
    37381 tatggaacct gaaatgaatc cattcttagg ttacagagca ataagacttt gcctagatag
    37441 aaaagatata tttaagactc aattaagagc tttatataga gctagtgttc atggaagatt
    37501 aagaatcatg ttcccaatga tttcatcttt agaagagttg ttacaagcta aagaagttgt
    37561 aaaagaagtt ttagcagaac ttgattctga aggtgtggct tatgctaaag atgtagaaat
    37621 tggtatgatg atagaagttc catctgctgc tgtaatatct gatgtattgg ctaaacacgt
    37681 agatttcttc tctataggaa ctaatgattt aattcaatac acttgtgcag ttgatagaat
    37741 gaatcaaaag ataagctatc tttacaatca atttaatcca gctgttttaa gacttataaa
    37801 gactgttata gacaatgcac ataaagaagg caaatgggca ggtatgtgtg gagaatctgc
    37861 tggagaccaa aaaatgatac caatactttt aggtatggga ttagacgagt tctctatgtc
    37921 tccaatatca atacttcctg ctagaaagtt aataacttca gttaaagagt cagatatgaa
    37981 aaaattagct gatgatgtac ttaatatggg tactgctgaa gaaataaaaa gctatataga
    38041 aaagactttt aatatataat taatgttata tagttactaa aattcatttt tctaaataac
    38101 aaaattatat tttacgaata aaaaaactat agtatatcat atatactata gtttttttgt
    38161 tatataaatt acgtatcaaa atttgtaaaa tgaatagata taattactaa atatgtgata
    38221 gtattggcta taataggata taaaaaataa tattgtaaaa aaaagtttat atttagtaat
    38281 gaaaatttaa cgttttactt gaaattatgt gttttgtaat gtattattaa ggctctaata
    38341 ggaacatttt catcaatttt tctatagtgg gggtaggaat tatgaggtac aaaaaaagaa
    38401 atatagataa gtcaagtgaa ctttcatttc aatctctagc aaaatatttt ataactttct
    38461 atatagtaat tatattaatt attctttcta tgttttgtat aaatacaata tgggttatga
    38521 aaaaagataa tcaagattta ttatctacaa catcaaatcg tattgaagat agggtaggag
    38581 aaacaattaa gctattgaac tctttgagta aagataatta cataatagat aatagtgtga
    38641 atggcataga taaaagtaaa gaactttcaa tgtatagtga tgaatttggg tatatgatga
    38701 tatgttttgt tgataagaat ataattgtgt gggatgaaga aggtggtaat attagtctag
    38761 ctggtcgtga ttatatgcag aaactttttg caacaaaaaa atatcaagtt acagatagtt
    38821 ttgcagcagg ggctgatgga aaaactttaa actacactat tgcatcacct ataataaaga
    38881 atggaaatgt agatggttgt gtatttgcag caatttactt tgatgagata aaggatatac
    38941 tcaaacaagg aaaaggtcaa cagcaacaga atttcatatt atttggaagt gaaaatcaaa
    39001 taatgaattt aacaagtgat gaaactgcat atggagagaa gtatatgaag ttatcgcaga
    39061 aaacaaaata tcttggaacc aatgcaaaaa aagtagaaaa ggatatgttt aataataaat
    39121 caggtgatta ttgggctttt gaaaatggaa aattatactt tatgtcctat aaaccaatta
    39181 agaacacaaa ttggagttta ttttgtaaag ttaatttctt agatattttt gcattaaatt
    39241 taattcctat gggagctatt ctatctgtta taactttagt atttattatt ttgatttgta
    39301 tggagaaaag cttcatgaaa aaacgaatgg aagttattga tatgctttta ggttctgttc
    39361 aagaattaga aaaacgtata tatcaaacag aaagacctag tgaagtagac tttaaagaaa
    39421 ttattcagct cacaagtaaa ggtctgactg atggattaac tggtgttgta acacgtactg
    39481 tattttttga ccaaatttat aatcgtgttg aaatggagga aaatgataaa ttatctgtaa
    39541 tttcatttgt tgatttagat gatttgaaat gtattaacga cttatatgga catgaaattg
    39601 gggatatggt tttgaaaaat gttggatatg tacttcgtga atatgagata aaatataatg
    39661 gtttaattgg gcgctatggt ggagatgaat ttgttatgtt gttatctggt tttacatcga
    39721 gagaagaggt ggaggattta ttggatgaga ttgctattcg cttacatact gaagtactaa
    39781 cagatgatgg tatcattcaa actcattgta gtgttggagc tgtagtatgt agtgtaaaag
    39841 acaataaaga tatagataat ttattaaaac aggctgatga agctttatac tatgttaaac
    39901 gtaatggaaa aggtaattat catttagttt aatgtatgtg gaaggagttt atatcatatg
    39961 aaaaatgtat ctaaaaaatt ttttgtatgt actattattg tattaataac atttttatgt
    40021 tttagtaaat ttgctattta tgtttttgac aaacaagaaa agaaagaaac aaaagtagta
    40081 gaaaacatgt taaatgtcta caagaataac attattttaa atctgactga aaaatttaat
    40141 tatagcaaag acttgacatc agttttagtt tcaaacaatt attctataga taaattaaaa
    40201 cctattgcag atgaaattct taaaaacaat tcttgcatat atatttcagt tgtagaaaaa
    40261 tataatgtag ctgcattttt ttctaattct gtcaaaaaag atattatcaa tactccaata
    40321 caggaactga attattctta ttcattagca aattctatca aaggattagt cgtagaaggt
    40381 ccttctaaag accagttttc aaatggagat gtgtttttaa ttactaatcc tatttataaa
    40441 aatggagagt actggggaga aattacagta gctttagatg ccaaaaaagt tgtagattct
    40501 tttaacttaa ataaattaaa agaatctgga tttgagtatg aactttggcg tgtacaccta
    40561 gataatggtt caaaatctac aatagaaatt tctactaaag attttaattt ttccaaatca
    40621 catgaaatta agtttaaact tccgactgtt tggactctta gcattgtgta caaaaatgga
    40681 tggaataata agaatataga ttttattgta tttgttatat tgttaattat ttctatatta
    40741 ataggtgtga tgacatttat ttacattgaa aagaagtcga ttagtaagga attaaatcaa
    40801 cagagtctta aaaatttaga aactggtatt ttgaatagag aaggtttttt aattaagttg
    40861 caagagcatc tgaatagaaa aaataatgaa atagtgttgc tgtatatatg tattactaat
    40921 tatagtaaat ttgctccagt tatgagcttt gaaaaaagac aagattatct tacacatata
    40981 gtaaaaaatc tagataatta cataaaaagt tctcatttta ttgctcgtat aagtgaggaa
    41041 ggttttgttc tagctttaga agaaaattgt gataaaaatg aattgcttaa cattgaaaaa
    41101 gggatttcct tagagctttt acgaaaaatt aaagtagaaa ataaacaagt atttttaacg
    41161 attggttatg gctcatctag gtgtgttgat gatagaaaag atgcagaatc tctgttactt
    41221 tcagctattg aagattatga gagaagattt ccagcaatgt ctcctattca tgattttact
    41281 aaaaagtgtg aagatatgct tgatgaaaag aaacagattg tatttggtga atatccagat
    41341 ttagaaataa acaagttgtc taaagtaata tacaaatatt ataaaaaagt acagcgtatt
    41401 atgtataaag attataatat tgatattgga aataggcgag ggtatatgcg tgatgtcgaa
    41461 gtattaattg attataattc tgagagaatg ttatacttat ttttaataga catatgcaag
    41521 tttggaaaat ttaatgaact gttttctatt gaaataggag atgttatttt aaaagaagtt
    41581 agtaacaaat taaaaacaat tttttctaat tatctatatc gtattaatgg agatgtattt
    41641 ttaggcattt caatagataa agaatcttac ttagatactt tacataaggt taatgaagta
    41701 tttaatagtt ctttaagtgt agaagatgta ctttttgatg taaaatgtaa tattggtatt
    41761 tgtcaatatc catatcatgg tgaaaatcca tatgaccttc tggaaaaggt acaaattgca
    41821 ttggagtatg caaaaaagga tgtcaaaagt aatgttaaag tttatgataa ggaattgaca
    41881 gaagagattt accatgaaaa taatattatt aaggatttaa aaaaaggtct ggaagaacaa
    41941 acactagaag tttggtatca gccaattttt aatgttagta aaaactgtta tataaaagct
    42001 gaggcactaa ttagattgag aaataaagag ggcggttatt attctgccta tgaagttatt
    42061 acttatgcag aaaagcatgg acttattaag gatgtaggtc tatatgtact aaaaaaggct
    42121 tgtgatgtaa ctacaaaaat aaaagataaa aatatagact ttgaacaaat gcaattaaat
    42181 ttatctgctc agcagattgt acataagcag tgtgcaaatg acatattatc atgtattgag
    42241 aattgtggtc tagataaaaa gtatatttct gttgaagtta cagaaaaagt acttatggaa
    42301 acttttgaaa ttgtaaatgt tactcttgat aaactaaaaa aagaaggcat tagcatagct
    42361 ttagatgagt ttggttctgg atttagtagt ataaattatc tggcaaattt acctattgaa
    42421 aatttaaaaa tagataagga attagtagaa caaattacct attctaaaaa acaatttgaa
    42481 ttattaaaaa ctatagttca aattactaag attaatggca tggatattgt agcagaaggt
    42541 gttgaaacaa aagaaactct ggatttagtt gtaacttcag gtgtgaattt gattcaaggt
    42601 cattattttt cagaaccttt aagtgaagat aaatttattg aacttatgat tgaagaataa
    42661 aggttaataa aataaagatt taaggtattg aaaaataatt aaaagtattt aataatagaa
    42721 ttagggaaga ataagtttat aagtaaaaac aattgattag tagttaataa aataaatgtg
    42781 atatccaaat aaatcctaaa tctaatttga gttttaatat agatagtcta aagtttgatt
    42841 attaaagatt taattgtaag ttgttacagt tgatgatatt gattagagat taaagtttag
    42901 agtagaaagt taccttaaat ttaaaaatgc aagataaccc aatctaaaaa ttataatcac
    42961 tcgataggtt taaggattta tttgtttatt ataaatagga gggtgtctca aaatgaactt
    43021 tttagtttat gaggcactct cttttatata gaattaaata tattttatta tttcaacaat
    43081 gaaaaagaag cttatctcta ttttgagaca gcctctttgt atactattat taatttaatc
    43141 aataacataa tttaaaatta taatactagt taagatttcc tgctttatta gtaaataatt
    43201 ctttaatagc attgtttctg gaaactaaat cgttatcaga gttgtttgtt tttttcataa
    43261 tcactgaata acgtttttta tttataaaaa atattaaaat cttatcatca tcaaaattgt
    43321 attctttata tctgtcgata gactcataac ctagatttag aatgtttttg tcttttatac
    43381 tatctacatc taaaatatat gatgggtcag cctttagtaa tatattaatt aaacattttt
    43441 cttcaccagc acagaataac tccatcttac ttgatataga tttagattgc tctgaagtta
    43501 tttttgcagg aataaggttg tcattatcat ctcttagaag ataaccatgt gtgtcttgtt
    43561 gatatactaa attaaccttt ttcttaggaa cactaatcat tttatctaaa tgtacataat
    43621 gatgattttc aacaaaacct tcatttaata tttcaacaaa gttattaatt ttacctaggc
    43681 aaaaagattc tatagattct ttacagaatt tatttgtaaa tggtattatg tttacgtttt
    43741 cctcgtctgt attccatgct atagcataat ccaacgaata tacttcttcc tctatatctg
    43801 caaaattata ttgtactatg tttcctttca aaattactcg acctccatct tataatatat
    43861 ttaatatact ttataaaact tatattatat ttaaataata tcataaattg aataaatatg
    43921 atatagtaaa taagaaaaaa tttgaaaaaa atcactataa atgagtaata aatataaata
    43981 gtgtatacta atgggatgga aaatgtccac tattaacttt attaccccac atatataaga
    44041 taaaattatt aatataaaat ataatctatc gacaatgaat agacttttaa ataaacttaa
    44101 tataaaatta attaaataag tgcttaaaaa cgatttactt taatgataga atcatattaa
    44161 aggaggataa ttttatggat ataaagaata aaattaaatc tatattttta ccagaaaaaa
    44221 atgactattt agatgatgaa gaatttgagt atgatataga aaataatgaa gaagatttaa
    44281 aggaagataa caaagtacat ttaaatgatt taagcagagt aaaatatgat tacagagagt
    44341 taaaagacat agaaaaccaa acagaagaga tgtgtctgct agcagtaaag caggatggta
    44401 ctataattga gtttgtaaag gacaagactt ataaagtatg tatggaagca gtaaaacaga
    44461 catataaatc tcttaagtat ataacaaatc aaaatgagga tatttgtata gaagcagtaa
    44521 aacagaacta cagagctttg tactacataa ataataagac agaaaatgta ctaattgagg
    44581 ctataaaaaa tgcatcaact tatgatgtca tggaagtatt taaatttgtg gaagagcaaa
    44641 cagaagatgt atgtctagca tttatagaaa gggcatctaa aaatgatgtt gcagagatat
    44701 taaaaggaat aaaagagcaa actccagcca tatgtttaga agctgtaaaa aaagatggaa
    44761 aatctttagc ttatgtaaag gaacaaagta atagtatatg tttagaagct gtaaaagaaa
    44821 actacagtgc actatcttgt gtaaaagagc aaactgaaga aatatgtata gaagcagtaa
    44881 aacagaatga ctttgcattg tattatgtaa atgaacagac agaaaaaata tgtatggaag
    44941 cagtaaaaag aagttatatg gctctacagt atgtaaataa gcaaacagaa gagatttgtt
    45001 tggaagcagt aagaattgat ggaagagcat tacagtacgt aaaagagcaa acagaagaaa
    45061 tttgcttgga gtcagttaga caaaatggaa aagtactgca atatgtaaaa aaacagactg
    45121 aaaatatatg tatagaagca gtaagaggtt catttgaaga acttgaaata aaagaaatat
    45181 taagttatgt aaagatacca acagaaagaa tatttgtaga agcagtaaag caaaatggaa
    45241 aaattcttaa atatgtagaa aatcagacag aattaatatg tttagaggca gtaagagaaa
    45301 actataatgc tttagcttat gtaaaggaac aaacagaaaa gatttgttta gaagcagtta
    45361 atcaaagtta tgaagcgctt aaatatgtga aagaacaaac agaagaagtt tgtctaaaag
    45421 cagtaaaaca agattataga atgttgaaat atgtaaataa tcaaacagaa aaaatatgtt
    45481 tagaagcagt aaagcaaaat tatagagctt tagaatttgt tgataatcaa acagaaaaag
    45541 tttgtcttga agcagtaaaa cagaatagaa aagcactaca gtatgtaaaa caaaaacaaa
    45601 gttaaaaggc taaaatatat agaaaacata tgcaaataaa taaaatttga tattttgtaa
    45661 taaataaaat gggtatctca aaaggaactt tttagtttgt gaggtactct ttttatatga
    45721 aatgaaatat atttttagcc ttttaacaat ggggaaaagg tttatttcta ttttgacata
    45781 ggctttttat gcatataaag cttgataaaa ttgttttatt ataattgttt tgttatataa
    45841 ataataagaa gaaaattata taggtctttt tttgaccagt tttacatttt taacaactag
    45901 ttttgtaaag tatattgaat tttctcaaaa aagaatgtac tctatatatg taaaattttt
    45961 ttggaggtaa aaatgtttaa aagatatgct gaaaaaatga catctgtttt aatttgtaat
    46021 aatatgatag ataataatga atctaaagtc tattcttatg gatttgaaat attaatagct
    46081 ttcatagtta atataaccac catgctgttt ataggttttt tatttggtaa atttacatat
    46141 gtattatttt ttttaatgtg ttattgtcca ataagacaat tttcaggagg gtatcatgca
    46201 gacaattatt ttagatgctt attaaccttt atttttataa ttttatctac aatcttaatt
    46261 atagaaaata taaatataga cttatttaaa aatattatta tgattattgc aagtgttagt
    46321 tgggttggaa tttgtgttct gtgcccaata gaacatagga gtaaccctat aagtgatagg
    46381 gaaaaattgg tttataagaa aactgctata tttatatcta cagtagtgtt attgataaca
    46441 attttaagtc tttctttgag tatatttgta gattatttca catatagcgc atttgccatg
    46501 ttttggattt ttgtgatgtt agtattaggt aagttaaaag ctaaagtata agtaaaatat
    46561 gtatgaggga gagttaagtt atgaaaaagt ttattgtaag atttatgaag tttgctagct
    46621 cattggcact tagcactgct attttgtcag ctaatagtac ctgtccttgg attattcatc
    46681 agcctaaagt acccaaagaa atcagcaatc taaagaagac aaattaaata caagcactta
    46741 tttatacaaa attatcagga aaaaagaaat tattatattt taataagatt aaaacaatat
    46801 aaaatcagat acaaaattta ttttatttat tttataggag cctaatacct atttggtaat
    46861 atattagtgc gccaatttag ggggatatag tgtatttaat gaaatgactt acggagagta
    46921 agtcattttt gtattgtatg tattttatgt aaacttatga tataatgaag ggtaaagttt
    46981 aattaaaata ataaaaaact ttagtataga tagtaattta ggaggtaggg tatgagtatg
    47041 atacataaat tttctatgaa tggatataat atcgttttag atgtgaatgg tggagctgtt
    47101 catgtgttag atgatgttgc atacgatttg ttagattttt ataaagaaaa aagtaaagaa
    47161 gaaatattag agatattaaa atcaaaatat caagaagaaa aaataaatga agcatatgaa
    47221 gaaatattaa atttggaaaa agagggtctt ttatatacag aagatacata tcaatatcat
    47281 ccaagctttg tacatagaga gcctgtagta aaagctttat gtttaaatgt agctcatgat
    47341 tgtaacttaa aatgtaaata ctgttttgca gctcaaggtg attttggagg agaaaaagaa
    47401 cttatgagtt ttgaagttgg taaggcagca attgactatt tgattgctaa ttcaggaagt
    47461 agaaagaacc tagagataga tttctttggt ggagagcctt tgatgaactt tgaggttgta
    47521 aaacaactgg ttgactatgg aagaagtgta gaaaaagatt ataataaaaa tataagattt
    47581 acaataacta caaatggtgt actgctaaat gatgagatta tagattatat aaatgaaaat
    47641 atgcataatg tagttttaag tttagatgga agaaaagaag ttaatgataa tatgagacca
    47701 actttaaatg ataaaggaag ttatgatatt acattaccac gatttaagaa acttgtggaa
    47761 aaaagagcaa aagataagta ttattatata agaggtactt ttacaagaga taatttagat
    47821 ttttcaaaag atgttatgca ttttgcagat ttaggattta aattaacctc tgtagagcca
    47881 gttgttggag atgagagtaa tccatatgca cttagagaag aagatttacc taagatattt
    47941 gaagagtacg aaaaatttgc tgtagagtat gcagatagac aattacaagg agatggattt
    48001 aaatttttcc attttatgat agacctaaat caaggtccat gtgtaataaa gagaataact
    48061 ggatgtggag ctggaaatga gtatctttct gtaactccaa atggagatat atatccatgt
    48121 catcaatttg ttggaaatga agaatttaaa atggcaaata tatttgatga agaaatagta
    48181 cttccagaaa atttaaaaaa tatgtttaga gaagctcatg tatatactaa agaagagtgt
    48241 aaacaatgtt ggaataagtt ttactgttca ggtggatgtc atgcaaatgc gataaacttt
    48301 aataatgaca tatcaaaacc atatgaatta ggatgtgaaa tgcaaagaaa acgtacagag
    48361 tgctctataa tgatacaagc taagttaatg ttagaaggag caaccaacta aatttatatt
    48421 ttaaaggagt tgtttatata tgattagaga ttatttagaa gataaacctt taattgacga
    48481 aagtgtattt gtggcaaaat cagcagatgt aattggaaat gttaaaatag gcaaagattc
    48541 aagtatatgg tacaatgcag tagttagggg tgatgaagga ccaataacta ttggagaaaa
    48601 cactaatata caagattgtt ctatagtgca tggagataca gaaactataa ttggtaacaa
    48661 tgtaacagtt gggcataggt ctatagttca tggttgtaaa attagtgata atgtgttaat
    48721 tggtatgggt tcaataatat tggataatgc tgaaatagga gaatatactc tgataggagc
    48781 aggtacacta attacatcta ataagaagtt tccaccaggt gttttgataa tgggttctcc
    48841 tggtaaggtt gttagagagc ttacagaaga agataaaaaa tatattgatg aatcttatga
    48901 atggtattta gaggcagcac aaaatcaaaa atattagttt aaagagtggt tgtttcaaaa
    48961 catatttaaa tctgttttga ggcaaccact aatttatttt attagatttt gttgatattt
    49021 tagttttcaa aaagtatttg attaaaccag atataaaatg tcaaaaataa aaattaactg
    49081 agttaaataa ttttaataaa attggtagta tatgtgataa aattaaatat taaagaggat
    49141 ataggatatt agaatatcaa ttggtgaaat aatgtcatat acgataaatt aaggtgtaag
    49201 tttttgggta tacctatctt aggagtgaaa agatttgaga ataagttata gaaatttaaa
    49261 gcgatataga gaaattggat atgttttaat aaagtatggt tttagtttta ttgtagaaag
    49321 actaaatata gaaggaattg cctataaaat accactattt gacccaccag aagaaataaa
    49381 aaatatgaca actggtgaga gaatgaaaag agttttagaa gaactaggac ctacatatat
    49441 aaaaatagga cagatattga gtacaagaaa agacttgtta gaccaggata taattgatga
    49501 aatatcaaaa ctcagagatg atgtagagaa atttgattca aatatagcta ttgatatatt
    49561 taaagaagaa gtgggtttaa gtatagaaga aatattctta gaatttaaag aagaaccaat
    49621 agcagcagct tcaattggtc aagtttatga aggtgtactt aaaacgggag aagaagtaat
    49681 cgtaaaaatt caaagaccaa atatagagaa aataataaaa tctgatttag agattcttag
    49741 aactattgca aatactttaa aagatttaaa aaaggatttt aatttagatt tagtacagat
    49801 gattgaagaa tttcaaactc aattaatgag ggaacttgat tatacatttg aagctataaa
    49861 tgcaactaaa ttctctagga tatttaaaaa tagtgatgaa gtatatatac ctaaagtata
    49921 ttcagaatat aatactaaga aaattttagt aatggagaaa gttaatggta caaagttaag
    49981 tgatgtagaa aaaataagga gactaggtta taacacaaaa actattgttg aaataggagt
    50041 taggtcattt tttacacagg tattatctca tggatttttt catgcagacc cacatccagg
    50101 taatatattc gtagttgcta aaaataagat agcatatata gattttggaa tgattggaat
    50161 tattgataat aaaactttaa accaattaaa tgaaattgca ttagcaggtg tagaaaagaa
    50221 tgttgacaag ataatatatc tattgataga aatggatgca ttaaatggag aggctgatat
    50281 taagggactt agacaggatt tactttatct aatacattat tactatgata tttctataga
    50341 aaaaataaat gtaacagata tattaaatga actatttagg ttttttagac agtataaaat
    50401 agtcatgcct gcacaatttg taactcttgc aaagacagtt ataacattag aaggaacaag
    50461 tagaacttta aacacagatt tttcttttgg ttctatggga aaagagttta tgaaacatca
    50521 ttataagagt aaatttaacc ctaaaaatgt tgttttaagt tcaagacaaa atgtagaaga
    50581 aatattactg gacataaaaa ctattccaaa gcaattaaaa gcaattttaa aaaatataga
    50641 aagaaataat ataaaaatgc aaattgaaga tgttaaaatg acgaggttag aaaattgtat
    50701 aatagagcta acatctcaaa tatctttgag tttagtgttg gcatctatta tagtaggttc
    50761 ttctcttata attgcatctc caaatataga aaataatata tggataaaat ttactgcaat
    50821 agcgggtttc tttatatcct ttataatagg cctttgctta gttataagaa gtattaggtc
    50881 aaaatacaaa aaagattagg gggaattaaa tttgaaaaaa tggatattga agtataaagg
    50941 taagatagag gaaagtgaat ttagcaaaaa acttaatatt tccccggaaa tctgccaaat
    51001 tttaaaaaat agagggatat gtactgaaaa agattcagaa atatttatga atccatcttt
    51061 agattattta agagaccctt ttttaatgaa agatatgcaa aaagctgttg atagaataaa
    51121 gttagcagtt gagaagaacg aaaaaatttg gatttacgga gattatgatg ttgatggtgt
    51181 atcatctaca tctatcttgt gcttatattt taagagtata ggttacaatg ttgattacta
    51241 tattcctaat agattagaag aagggtatgg tataaatgaa gatgctatta agcttataag
    51301 ctctagggga tgtgacttga ttataagtgt tgactgtgga attacatcag tgtctgaggt
    51361 caatacagcg aatgatttgg gcatagatgt tataattaca gaccatcatg aatgtcaaag
    51421 tgaaattcca tcagcctttg cagtaataaa tccaaaacaa gaagattgta attatccatt
    51481 tgattcacta tgtggatgtg gtgtagcatt taaaatgatt caagccttga ctccaaaaga
    51541 agaatttaaa actagtatgt ataattattt ggaaatagta acactagcaa ctatttgtga
    51601 tattgttcca cttatagatg aaaatagaat aattgtaaaa aatggtttaa aatcaatgaa
    51661 agaaggcaaa aatattggat taagggagct tataaaagtt tgtggtgtag aaagtgataa
    51721 gataggttct tctcatatag gttttgcaat aggtcctagg ataaatgctt caggtcgatt
    51781 gggatattct tacttaggag tagagctatt tactactcaa tcacaagaag aggcagtaga
    51841 aatagctagt atattggaag aaaaaaataa tgaaagacag atgatagaag ctaagatgta
    51901 tcatgaagct gaagaaatgc taaagtctaa tagcagatac aatgatgaca aggtgttggt
    51961 tttagctaaa gagggttggc aacatggaat aataggaatt gtagcatcaa agttaactga
    52021 aaaatactac aaaccaacaa ttcttctagg tatagaaaat ggggaggcta ctggttcagc
    52081 gaggtcaata aaaggattta atatatttga agctctcata aagtgcaaag acttgatgac
    52141 taagtttggt ggtcatgaac aagcagcagg gttatccttg gattcagaca atgtagaaat
    52201 tttagcaaat gaaataaata aatttgcaga ttataattta actgaagatg atatgataga
    52261 gaatgtaaat gttgagtttg aattacaaga aaatgtaata aatttaaatc ttgtagaaga
    52321 attacataag ttagaaccct ttggattaaa taatcctaat cctagattta tagttagaaa
    52381 ttatatttta aaagatttga aagttatagg taagaatcaa caacatctga aattaagcat
    52441 agaaaaagag aaaagctatg aatgtatagg atttaatatg agtcatttaa aatcaatgta
    52501 taaagtagga gacaaggtag atgtactatt ccaattagat gaaaataact atatgggaaa
    52561 taggaaagta caatttttac ttaaagatat acgattggct cgacctaaaa gtgcaagtaa
    52621 tgacaaactt tcattgaaat taatgtcaaa aataatacca aaagatactc aaagcctgta
    52681 taatatatct gtgtctgatt ttgaattatt tgatggaaat acagatataa atatatttga
    52741 ttattttgaa aaagatacac taataatatc taattctata aatggatttt atagagcaat
    52801 gtcagatata tcacttatag atttggattt taacataaat tacaatatta ttgaagatga
    52861 tagcaaaaat actgataaat tagagcttat attttctcct aatattgata aaatagactt
    52921 aaaaagatat aataatatta ttctttatga ttatttatac aataaaggcg aatattcgta
    52981 tatatatgag aataaaagag aagaaagtga aattataaaa tattataata aaacagacct
    53041 attatattta aagaatgtag ttagtaatat agttccatca agagatgaat ttataacaat
    53101 ttataaacaa gcactcataa aaaaagaaat tgatttggat atggtaaata taagggaaac
    53161 ttttaatgta attccattaa agttttttac gatattaaat gtatttagag aattaaattt
    53221 acttgacttt aatttaaatt atgaaaaaaa ttctgtactc ataagaatat tgccaaaacc
    53281 acagaaaaaa ttagacttaa atgagagttt aatactcaat aatctaaaaa atttagaaaa
    53341 acaatacaat agcagttatt aggaggcgtt tcccatggat ttaaaaaact ttataaggaa
    53401 tattgatgat ttcccaaagc caggcataga ttttaaagat gtgacaactc tatttaaaga
    53461 tggagatgca tttaaatatg cagtggattc tatagttgaa gaattgaaag ataaagatgt
    53521 agatttagta ataggaccag aagcaagagg atttttgatg ggtacacctg tagcatatgc
    53581 tttaggagta ggatttgttc caattagaaa acctggaaag ttaccaggtg aagttgagag
    53641 ttatgagtat ggattagagt atggtacaga tactttagag atacataagg atgcaattaa
    53701 aaagggtcaa aaagtagcaa tagtagatga tttattggct actggtggaa ctatggaagc
    53761 cgctgccaag cttgtagaaa aattaggtgg agaagtagtt tctatgcaat ttttgattga
    53821 gctaaaattc ttaaatggga gagaaaagtt gtctaactat gatgttaatt ctcttataaa
    53881 atactagtac ttttataata gttggtataa caccaactat tttcatatat attaaaattt
    53941 tatacaaaat aggtggttat atgcatgata aagaattaca agaaataatt gaaaaaataa
    54001 aagtttatgc acctaatgca aattttgaaa tggttgaaaa agcctataat cttgcaaaaa
    54061 aagcgcatga aggacaatat agaaaatctg gggaaccata ctttattcat ccattagcag
    54121 ttgcaaatat tttaatagag atggaattag atattgaaac tataacagca ggtttacttc
    54181 atgatgttgt agaagataca gaatatacct atgaagacat aaaaaaagaa tttggcaaag
    54241 aagtagcgga tttggttgat ggagtaacta aacttggtca aataaaatat cgttcgaaag
    54301 aagaaactca atctgaaaat ttaagaaaaa tgtttttggc aatggcgaag gatataaggg
    54361 ttatacttat aaaacttgct gatagattgc acaacatgag aacattaaaa tacatgcctc
    54421 cagaaaaagc aaagtataaa gcaaaagaga cacttgaaat ttatggtggt atagctcata
    54481 gattaggaat ttccaagata aagtgggaac tagaagacag agcattaaga tttatggacc
    54541 cagaagggta ttatgattta gttagtagag tatcaatgaa gagaagtcaa agagaggatt
    54601 atattcaagg aattgttgaa cttcttaaag ataagtttaa agatttaagt ataccatgtg
    54661 atgtatatgg tagaccaaag catttttaca gtatatatag aaagatgcaa aaaaaacata
    54721 agacttttga agagattttt gatttaacag cagtaaggat attggttgat aatgtaaagg
    54781 attgctatgc agtacttggt atagttcata cattatggag acctattcca ggaagattta
    54841 aagattatat agcaatgcca aaacccaata tgtatcaatc attacacacc actgttgtag
    54901 gtcctgatgg agaaccttta gagatacaaa taagaactca tgagatgcat aatatagctg
    54961 aaaatggtat agcagcccat tggaaatata aagaaggtat ctctagcaaa gagtcaaagg
    55021 ttgaagaaaa acttcaatgg ttgagacaga tgatggagtg ggaaaaagat ttaaaagacc
    55081 cacaagagtt tatggatgca cttaaagaag atgtatttaa tagtcaagtt tatgtattta
    55141 cgccaaaagg agacgtaatt gaattaccag cagaatcaac acctatagat tttgcctata
    55201 gagttcatac aaatgtaggt aataaatgtg taggagctaa aattgatgga agaatagttc
    55261 ctattgatta taagcttcaa aatggtaata ttgtcgaggt acttacatca tctaattcta
    55321 atggaccaag tagggattgg cttaatatag tgaagacccc aaatgcaaaa agtagaatta
    55381 gacaattttt caagaaggaa agaagagaag aaaatgttga ccgtggaaat acaatattag
    55441 aaagagaatt taagaagcat gatataccac aaaaagaccc tcttgttgaa aaatatatgg
    55501 cattagttgc taagaaattt aatcagccaa gtgttgagga cttaattgcc actgtaggtt
    55561 atggtggtat aatgtcatct caagtggtat ctaaggtaaa agacctatat ttaaaagagg
    55621 ttaaaaaagc taaaaaggaa caacagatac aagaagaaga tttaaataaa cacaatataa
    55681 gtgaaacaga atacagtaaa aagagaaaga aaaacgcatc acaaggaatt atagtaaaag
    55741 ggcttgacaa tatcttagta agatttgcta agtgttgtaa tcctcttcca ggagatgaaa
    55801 ttgtaggata tattactaag ggtaggggag tagccataca cagagctgat tgcccaaatg
    55861 caaacaataa tggtgatttc ttccaaaata gattggtgga ggtttcatgg agttcagcag
    55921 gaaaaggtaa gtttgaagcg gaaattcaaa taaaagctat tgacagaaga ggaattgtta
    55981 atgaaataac tcatattgtt gcaatggata aacttagttt aaacggaata aatgcaagaa
    56041 aaggtaagga tagtattgta agtataaact tacttgtaga ggttaatgac acagaggaat
    56101 taaaaattct aatgaaaaaa ttaaaagcaa ttcctggtgt agaaagtatt tatagaatga
    56161 caaattagag ttaaaataat agggaggaaa ctatgagagc agtagtgcaa agagtatctt
    56221 catctaaagt tacagtagat gaaaacacta taggtcaaat aaataagggg ttactagtat
    56281 tgttaggagt gactcatgat gataaatcaa gtgatgtaga ttatatgatt gataaaatat
    56341 tgaatctgag aatttttgaa gatgaaaatg acaagatgaa tttatctcta atggatatag
    56401 gtggagagct tttagtagta tctcaattta ctttatatgg agattgcaga aaaggaagaa
    56461 gacctggatt tagtaatgca gctagaccag aacttgcaaa taacctttat gaagaatttg
    56521 taaaaaaagc aaaagataaa ggtgtgacag ttggtacagg tcaatttgca gctcatatga
    56581 tggtagagtt aactaatgat ggtccagtaa caatactatt agactcaagt aaatcttttt
    56641 aagggggaaa actttaatga ttataaaaaa atttgtagat agttattttg gagtaaatac
    56701 ttatgtatta ggtgatgaaa agactaaaaa atgtgcagtt atagacccag gtggaagttt
    56761 agtagagaca ttaagttttg taaaagaaaa tgaattaaat attgaatata ttatccttac
    56821 tcatgggcat ggagaccata taggatatgt taaggatatt aaagaaaaaa ctggtgctaa
    56881 agtagttgca catgttgatg aaaaagaatt attaaatgac aaaaataaaa atctaagtta
    56941 tacaatgaga tgtggagcgc aagagtttga tgcagatatc tatgtaaatg ataaagacaa
    57001 gcttgaactt ggtgaattaa aaatgacttt cttgcatact ccaggacata ctcaaggatg
    57061 tatgtgtata agagttgaag atgaaatgtt cacaggagat actttgtttg ctggaagtat
    57121 tggtagaact gatttatata gtggagactt taaccaaatg gaaaaatcac ttaagaaatt
    57181 atgtaaatat gaagatgctg ttagagtata tcctggacat ggaccaacca gtactctagg
    57241 ggttgaaaag aagacaaatc cttacatgta attttatatt agtatttaaa aaagtataaa
    57301 atatttaata actatattag tgagggggtt cttctactgt taaatagaag gagttaagtt
    57361 gatgttgtat gtttttttaa aaggacatga ttataagtat gaagtagcag aacttataaa
    57421 attgtttact agtgaattta agtttaaaga ctctaatgct aacaataata tagagtcaaa
    57481 gcatttaata aatagattga tttatgagaa tggtgtatta ttctcaagta ctgaatacta
    57541 tgaaaatgga aacttaaagt acgagtcaat acagaatata gaaaatatga atcttgaatt
    57601 tttagatgga tttgatagca gcaaaacgat tgaagaattt cttaatagcc tagatagtga
    57661 aagtaagagg aactttaaaa agctgtgtaa agaaaatatc aaaaaaagca tgtttttagt
    57721 gcttaaacaa gtatttaatt cttatgtacc atggggaatt ttgactggta ttagaccagt
    57781 caaaattgtc cacaatttaa tggataaaaa gctagatgat aatagcataa gaaccattct
    57841 aaaagataat tattttataa tagatgagaa aatagattta gctcttgaaa tagctaaaag
    57901 agagcgatta tttatgtatc ctatagataa aaataaaatt tctctttatg taagtattcc
    57961 attttgtcca actagatgtg tatattgttc atttccttca aattcattaa aacaatttgg
    58021 acatttaaaa agagaatatg tttataaatt gattgaagaa attaaggggt ttgccaaagt
    58081 tattaaggat actaagaaag aagttgaaac tctatatatt ggtggtggaa ctccaactac
    58141 acttgatgag gaagaattgg atttgcttat aaattcattg ttcaatgaat tagatttaag
    58201 taaaattaaa gaatttactg tagaagcagg tagacctgac actattacag aacaaaaact
    58261 aagagtgtta aaaaaacaca atgttagtag aattagtata aatcctcaaa ctatgaatga
    58321 tgataccttg gtaaagattg gaagagagca tagagtatct gatttagtag attgctttaa
    58381 tatggctcgt agaatgggat ttgataatat aaatatggat ataattttag gtcttataga
    58441 tgaagactta aatatggtaa agaacacatt ggaggagata aaaaaacttt ctcctgaaag
    58501 ccttacagtt catacattag ccataaagag agcatctaac ttaaatataa atatggatag
    58561 gtataaagaa catctaacac aatatgaaga aatggtaaaa atgatagatt tatcaatgaa
    58621 atatgcaaaa gatatgggat taaatccata ttatatgtac agacaaaaac atatgttggg
    58681 aaatttagaa aatataggtt atgctaaaga aggatatgag tgcatttata atatacagat
    58741 tatggaagaa aaacaaagta actatgcatt aggtgcaggt gctatatcga aatttgtcta
    58801 tgtagatgaa gatagaattg aaagagtaga aaatgtaaaa aatgttgaac aatacattga
    58861 aagagtagat gaaatgataa aaaggaagaa agaagaggta tataaaaatg ttgactaaag
    58921 ctcctagagg aactaaagac ataactccaa aagaggctta caaatggcgt tatgtagaaa
    58981 ataaatttag agaaatatgt gctttatatg gatatgaaga aatggtaaca cctatatttg
    59041 aacatacaga acttttcaag agaagtgttg gagatactac agatatagtt caaaaagaaa
    59101 tgtattcttt taaagataaa ggtgatagag aaattaccct aaagccagaa ggtacagcag
    59161 gtgtagtaag agcatttata gaaaataaat tatatgcaga tactcaacca acaaaattat
    59221 tttatgtgac accttgtttt agatatgaaa gaccacaagc tggtagacaa agacaatttc
    59281 accaatttgg aatagaagca cttggaagtg atactccttc aatggatgct gaaataatcg
    59341 cactagctgt tcaatttttt aatgaagttg gattaaatga tttggtagtg agtataaatt
    59401 cagttggctg tccagtttgt agaaaagagt acaatgcttt attaaaagag tatcttgact
    59461 caaaagctga tatattgtgt gatacttgca atgagagaag agaaaaaaat ccaatgaggg
    59521 ttatagactg taaaaatcct acatgtaaag aaaatatcaa agatatacca tttattgcag
    59581 accatttgtg tgatgattgt aaatctcact ttgataaact tcaagaatac ttaaaggaaa
    59641 tgaatataaa ctttgtaatt gataaaacaa tagttagagg cttagattac tatagaaaaa
    59701 ctgcttttga aattatatct aatgatatag gagctcaaag tactgtatgt ggtggaggaa
    59761 gatatgatgg tcttgttgaa caattaggag gaccaaaagg tataagtgga attgggtttg
    59821 gactaggaat tgaaagactt ttacttacac ttgaaggtaa tggaattgaa atagaaaacc
    59881 ctcaatctac ggatatattt atagtaacta taggtgaaga agcaaataca agaagcttta
    59941 aattgttaaa agacttgaga caaaatcata taagtgcaga taaagaccat atagagagaa
    60001 gtgttaaagc acaatttaaa tattcagata aaataaattc aaaatttaca atagtaattg
    60061 gagatgatga gcttaaaaat gacactgcga cattaaaaaa tatgaaaaca tcagagcaaa
    60121 ctactgtaaa attaagtaca ttagttgaag aattaaagca aaagctgtaa aataagaaag
    60181 tatgatgttt tgtgtattag ataaatatat agcattaaaa ttaaataaaa tggaggtagt
    60241 atcttggaaa ctttaaaggg tttaaagaga actcactact gtggagagtt gagagaaaaa
    60301 aacataaatg aagaagtcgt acttatggga tgggtacaga aaaaaagaaa tttaggtggt
    60361 cttgtatttg ttgatttaag agatacaagt ggattatgtc aaatagtttt tgatacagat
    60421 gtagataaag aagcttttga aaaagctgaa aaattagggg ctgaatttgt aatagctgta
    60481 aaaggaaaag tatgcgaaag acaatctaaa aaccctaata tgctaactgg tgatatagaa
    60541 atatttgcaa ctgaacttag acttttaaac aagtcagaaa ctccgcctat ttatataaaa
    60601 gatgatgatg atgtttctga agcactaaga ttaaaatata gatacttaga tttaagaaaa
    60661 ccatctatgc aaagaaattt aaaattaaga cataaagtaa tgaatattac aagaaattac
    60721 ttatcaaaca atagattttg cgaaatagaa acaccatttt taatagctcc aacaccagaa
    60781 ggagcaagag attatctagt accaagtaga gttaatccag gaaaatttta cgcattacca
    60841 caatcaccac aattatataa acaattattg atggtaagtg gtatggatag atatttccaa
    60901 atagttaaat gctttagaga tgaagactta agagcagata gacaaccaga gtttacacaa
    60961 atagactgcg aaatgtcttt tgttgagcaa gaagatgtta tgagtatgat tgaaggtttg
    61021 cttgaagcga tatttaaaga agttttagat gtagaattgg cacttccact tcctaagatg
    61081 acttatgcag aagctatgtc taaatatggt tcagataaac cagatactag atttggatat
    61141 gagttaacag atatatctga tgttgtttgt aactgtggat ttaaagtgtt tgctgatgct
    61201 acacaaccag gaaaaagtgt tagaggtata aacgtaaaag gcaaagctga cgactttact
    61261 agaaaacaaa tatcatcact agaagaacat gctaagacat atagagcaaa aggtcttgct
    61321 tggatgaaag taggacaaga aggagtaact tctccaatag caaaattctt taatgaagaa
    61381 gaaatgaacg ctatacttac aagaatgaat gctgaagtag gagatttact tttatttgta
    61441 gctgataaaa actcaatagt atttgatgct ttaggacaag ttagacttga agtagcaaat
    61501 aggcttaatc tattggataa aaatgtatat aacttactat gggtaactga gttcccagtt
    61561 tttgaagaag atgaagaaac aggcacattc tcagcaatgc atcacccatt tacatcacct
    61621 atggatgaag atttagacaa gttagaagaa ggtgataagt catctttaag agcgaaagct
    61681 tatgatattg tattgaatgg ttatgaaata ggtggaggaa gtgttagaat atcaaattct
    61741 gatgttcaat caagaatgtt taaagcactt ggttttacag aggaaagagc taatgaaaag
    61801 tttggttatt tattagaagc atttaaatat ggtactcctc ctcatgctgg tctagctttt
    61861 ggtcttgata gacttgttat gttacttgca ggaactgata atataagaga agttattgca
    61921 ttccctaaaa atcaaaatgc tgtttgccct atgacaaatg ctcctacatt ggcggaagat
    61981 gagcaattag aagaattaag tataaaagtt gatataaaag ataatgaata atatgtagtt
    62041 gcaagaaact aaaatgtaaa aagtctggat ataaaatata tttatattca gacttttttt
    62101 attagaatta ttttatattt tttctctata tattttcata aattatactt atattcttaa
    62161 ccaatataat taaaatacta tgtttaaaaa ttttacataa acttgattat tttagaaact
    62221 acttctgtaa tgagtacacg attttaatta aagaatatat aacaaatttg aaataagtct
    62281 aatatatgac ttaatagatt aaattaaaat aataaatttg gactatttat ctatttataa
    62341 cttaaattat atcaaattga taacaaacta gatattatac ttttttgtag aatagaatta
    62401 caattatata aagaaaaatt ctattaatag tgaaaaaaaa gtagaaaaaa gtagaaatta
    62461 ttcttttata aagaaaggga gggataatat tgcaagagag agaagaatta gttttaaatc
    62521 cagttccaaa agaggaaaga gttggatggt tagctccatt gtttaatatg cttggttcta
    62581 acatagctat atctgaacta atggttggag gaactttaat tttaggaatg actctttcta
    62641 atatgattat tacatcaatt atagggaact taatattagt tgcaattatt atgatacaag
    62701 gttatatagg ttacaaagaa gggttaaata cgtatgtatt agctaagggg gcatttggag
    62761 agataggagg aaagtatctt atatctctat tacttggtat aactagtttt ggatggtttg
    62821 gtgtacaagc aggggttgca ggactatcag tacaaaagat atttccaagt gtaaatctaa
    62881 cattagttac agttatactt ggattattta tggttgtttt tgcactgtat ggctttaaag
    62941 ctatggctaa atttaattac ttagttatac caccacttat gatattaatg gtgtggggag
    63001 tttttaaagc tttttctact tatggagttg aagctattta taattatact cctcaaacaa
    63061 ctatgagtat ggttgaaggt cttaatattg tagtaggtct tgttatagtt ggtgcaatta
    63121 tatcacctga ccagttaaga tatacgagac gagtaaaaga tatttggatt atcagttttt
    63181 taggtctagg gattatttca ttattccaac aagttgcagc tggtgtaatg tctatgggag
    63241 cacctacttg ggatataaca gaagtattgg ctaatttagg ttttggatgg gtagcgtttg
    63301 ttattttaat acttgcatct tggtctacaa acgtatcaaa tgcttattct ggtggattag
    63361 cattaaaaac tatttttcca aatgtaaaaa gaaatgtttt gactttagtt gcaggtctaa
    63421 taggtacaat aatagcagct actggtataa tatttaaatt tcagtcattt ttatctttct
    63481 tgggaatcgc agttcctgca atagctggaa ttatgtggtg tgagtattat tttatacaag
    63541 gaagaactta taagcataga gaaggaataa attggattgc agtaataagc tggttaatag
    63601 gttttgcagc gtcgtattat agttcaaaaa taaatttctt aatacctccg ataaatggaa
    63661 ttgtagtgag tatggttatt tattatatat taatgaaatg ttttggaatc aaagataaat
    63721 aaagggggca attacatggg tcgtaaggtg aaaataggta taattcaaca acacagtgta
    63781 cttggagatg ttaaaaaaaa tatagaaaag gcagtagaga tgatagatga cttaggaaaa
    63841 caaggggcag atataatttg tttaccagaa ctatttgcta caggatataa tttagagtct
    63901 ttaggtggag ttaaaacatt agaattaata agagaacata ataagtacat agaggaatca
    63961 atgtcagaag ctgctaaaag aaataatgta tacctgatat ctccatatgg aaccttagaa
    64021 aaagggtcta cacatgttta taattcagca gttatatttg atagaaaagg taagattatg
    64081 ggagaatact gtaaaaatca tctgtggtca ttagaagcag tatactttaa aggaggggaa
    64141 aaagtagagg tatatgatgc tgattttggt agatttggtg taatgatatg ttatgatgca
    64201 ggttttccag aagtatccag agaattgaca ttaaaaggtt ctgaaataat atttatacca
    64261 tctgcatgga gaatacaaga tgaagatatg tgggatttaa atgtatctca aagagcttta
    64321 gagaacactg tatatacagt aggtgtaaat ttagtaagta atgactctaa tttaatacta
    64381 tttggaaaga gtaaaatatg caatcctaga ggtactgtaa taactcaatt agatacatac
    64441 agggaaaaat atgtattatc agagattgat ttagatgaaa taaaaaagta tagggaagat
    64501 atcccctatt tgaaagacag aaaaagtagc tataacatat aattctatac tataatacaa
    64561 gttcaatata aaatgataaa aagaggatgt atcaatatta agattaaatt tattatactt
    64621 tgatatatcc tctttaatat tatcaacttt gatttaaata tttttaaaat agttgataag
    64681 aaagtttttg aacaacaaca cagctttaga ttcatagttt tcgctaaacc atgaaagatt
    64741 taaatatctt ttaaattcaa tatctttgat atgtaacaac ttaatctcag ggtcttgaga
    64801 taatccccat gattttccac atataaatcc aactccttga agtgatttta taagagcata
    64861 aattgtatat ggtgaatcag actcaaatgc tattttgggt ttgaaattag ctgattcgca
    64921 caggatatca attacctctc tataattctc acccttcgtt ataactataa agttttcatc
    64981 tgaaacttcg cttagatata cttcatcctt taatgataaa ggatggttta ttgaaactcc
    65041 taatagtatt tcttcgcatg ttaaagttat gctattttct gagtttagct ttgtaaatga
    65101 agaagatatg tacaaatcaa aatcactttt tttataagat gatggcaaag tatgtgacac
    65161 attaaaagta atattgggat atagttttct gaaattactc aaaagtgatg gtaacacatt
    65221 agccgctgca ggagataata tctttacttc tcctgaattt tctaaagaag tgtcttgtaa
    65281 ctcctttttt gaactttcta ctaaatctaa aatgctatct actcttttta gaaacaatct
    65341 tccatactca tttaaaacaa tatatcttcc ttttctgtca aataactgaa ctccaagttc
    65401 tttttctaag gaagatatag ttttgcttaa agctggctgt gctatattta acttgtgtga
    65461 tgcttttgtt atgtgctcca ttctagcaac agtttgaaaa tacttaagat gcaataaatc
    65521 catagtataa aatacacctc ttttaatatg acttgagtta tatcaatttt ataatcaact
    65581 ccacattata cattataata taaagtttat ataataaact acaatatatt aaaaagttat
    65641 ttaaattgtt atttatattt tgtacataat ctaattaaaa aaagtaactt taaatgatta
    65701 actaaggaaa tgttgttaca aactttagtt atataaaaaa ttcatttgat gagcaaagta
    65761 ctaatatcaa gtaagaataa aagcttatta gataagaaaa ataatatttt ataataatga
    65821 tgttacttaa attattatgt tatactattt taaataggaa aaatttagat actataattt
    65881 tagggggagt caagatgaaa ttaactaaat caatatcatc aatgctgtgc ttatctctag
    65941 ttttaagctt atcaccagta gcatatgcaa atgaaataag tagaacaaca gttgagaata
    66001 ctttagtagg tcaggataga tatcaaactg ctgttgaagt aagtaaaaaa ggatggagta
    66061 gtgcaaatga ggctgtagtt gtaaatagtg aatctattgt agatgcatta gctgtaacac
    66121 catttgctaa attaaaaaat gctcctatat tattgacaga aaaaaataat ctaaattcac
    66181 aaactgagaa agaattaaaa agattaggag ttaaaaaagt ttatataatt ggtctatcta
    66241 gttctgtatc aaatgatgtg caaaaacagt tagaatctaa taatttaact actgatagag
    66301 ttggtggtag tgatagatac caaacagctt tgagtatagc taaaaaaata gaaggattaa
    66361 aagatatatc agaaatagct gtagtaaatg ggtacacagg tcttgcagat gcagttagta
    66421 taggttctgt agctgctact aatggaatgg ttatacttcc agtatctgat gcatctggta
    66481 tatctagctt taaagatttt atagaatcta agaatataaa taaatcatac ataataggct
    66541 ctactaatgc tgtatcagat aaaataaaac aaagtttacc taattcagaa agaataggtg
    66601 gagcagatag aaatgaaact aatggtaaag taatagaaaa gttttataca tctaataaat
    66661 taaacaatgt atttgtggct aaggatggaa tgaaaaatca aaatcaactt atagacgctc
    66721 tagcagtagg agtactagca tcaaaagaaa attctcctgt actaatcgta ggagaacaat
    66781 taagtgcaac acaaaagagt gtattttcga ataaaaatgc tacctctata actcaagttg
    66841 gtagtggagg aaatgaaaat gcatttaaag aattaaaaga tttacaggca aatagtaaca
    66901 ataagagagt aatgtatgta actaatacag ataaggtaaa tataagaaat gatgctacaa
    66961 tagaagcttc tgttatagga tatctaaata atggtgatga agtagaagtt ttagatgtgt
    67021 taaaaactgg atgggtaaaa ataaaataca atgaaggtat tggatatgtt agtgggtctt
    67081 atttgacaaa taataagcct gataatagta atgaaaatat aaaaataaag tatgtaaaag
    67141 aaaaagatgg tctaaatgtt aggaaaggac caagtacaga agatgaaaaa ataggtcacc
    67201 tttcatatgg aagcaaagta gaaacaatag aaatgtttgc tactggatgg gtaaaaataa
    67261 agtacaatgg tggatatggt tatgtaagta atgattactt atctgataca ccagttattt
    67321 aattataagt aacaataaaa aaactgcttt aatttgtaaa gcagtttttt tataaaaatt
    67381 taagtctaat aactatttct attttgatac cttaatcctg ggatttatta ttatggatat
    67441 tatcaacata caaacactcc aaatccagtg tctaattcca aacttagata ttaataaatt
    67501 cagtcctgct atggtaaata agcagtattt aattacaatt aaaagtgtat ttatagaaag
    67561 ccccctcata gaaagtatcc taaatccaat aatagacatt ctaagtccta taaatgccaa
    67621 taatatacct gcaatatcct gaattaagta atagtattca aatttcatat tcaatcaact
    67681 cttctctgag cagtatcaaa tatttctaac tcttcaattt catcatctgt gtatgtaagc
    67741 atagtaaaac cagttacacc ataaataaat gaaattatag gtgtaatcca acttaagaaa
    67801 caatatggaa taaattctag tggacttaca ccaagagtct gagcacagaa aacagcattt
    67861 gaattccatg gtattaatgg accaccaagt gtagctgtat cttctataat tctagataga
    67921 ttttgtggtt ttaatttaaa ttctttgtat attggagaca ttagagttcc gacaaataca
    67981 gaagtgaaca tcattgatga actaaatgca tttgcaaagt agcttactat aaaagtagac
    68041 ccaaccaatt tagttcttga ttttcctatt ttagttataa gaggttgaag cagtacttct
    68101 aagaatccag ttttttggag aataccagca ataacgaaaa ctacaaatac tagtaaaacg
    68161 gtttcagcca tactcattat tccaccacga tttaatagtt tgtcggcata gacaaatcca
    68221 gtatctatag taaatcctga tagcatgtaa tttaaaacat cacctatttt ttctccttct
    68281 tgaaatactg ctataataag tcccatgata gctgaactta gtatagatat aatgggtggc
    68341 ttttgtagca ataaaagtaa taataaaaat attattggaa tcattgctac taaaccaata
    68401 tgaaagtttg aatttaatac atccttgatt tgatttattt gaacatagtc tatagtatta
    68461 tttgaatact taaatccaat tactgtatac agaactatac atattacgta tgcaggtcct
    68521 gtggtataaa acatatgctt catatgtgta attacatctg tcttacaaac tgctgcagct
    68581 aagtttgtag aatctgatag aggtgacatc ttatctccaa agaaagcacc agaaatgact
    68641 gcaccagctg ttaaaccaag aggaataccc atactagtac caatactcat cattgctata
    68701 ccagaagttc caagagtccc ccaagatgta ccagtagcaa cagaagttaa tgaacatacg
    68761 attaatgttg taagcagaaa atatttaggg gttattattg ttagtccact atatactact
    68821 gttggtattg taccagcagc tatccaagct gctattagta caccaacaga aagtataatt
    68881 aagtttgatt gaaaggcatc tttgccaact tcaaatccaa aagcttctat ttcatcatta
    68941 gtataaccaa gtttcatggc tgcaggaact actataagcc atgaaagtaa aaacattgta
    69001 gttatagaag cattaaatac aactatacca actgatgtta gagctattat tgcaagcatt
    69061 actaacaagg aatatctaaa tgaaggtatt tttctttctg tattcatttt catagtgcaa
    69121 attctcctta aatattttta gttaattgca ttttttattc ttataagagc ttcttcaagc
    69181 atacttcttg gacaagctaa gtttattctt tgatacccac ttcctccaat gccaaagctg
    69241 tttccttgat ttagagcaac tttacctttt tgtacaagta tactttctag ttcctcatca
    69301 cttaatccaa gtgcactaaa gtctacccat aataaataag taccttctgg ttttctaact
    69361 ttaagttttg gcatattttc atttatatat tttatagcaa aatctatatt agattctaaa
    69421 tattctaaaa atgattctag ccaagattca ccattattat atgaagcttc agttgcaact
    69481 aagctaaagc aattatttct ctttatatca attctggtaa aggcatcatc taacaattta
    69541 tagtattttt catcaggtag tattacatat gatgattgaa gaccagctat attaaaagtt
    69601 ttagttggag ccatacaagt aattgtattt ttttcaaatt ctttagaaat agatgccata
    69661 ggaatatgct tatgtttttt taatataatg tcactatgta tttcatcaga tatgattttt
    69721 acattatgct taagacaaat atctcctagt ttttttaatt catcttttgt ccatactcta
    69781 ccaactggat tatgaggatt acaaagtatg aataatttta catctttaat cttgttttca
    69841 atgtcttcat aatccattat gtagtttcca ttttctaatt tttgtaatgg gcttataatt
    69901 agttctctat tgttattttt tacaacacta ttaaaagggc tgtaaactgg ttcttgtatc
    69961 attattttat catttgcttt tgtgagttca tttattaaaa gacttatagc tgggataaca
    70021 cctggactat aaattaacca ctcacttttt attttccagt tatgtctcct atctagccag
    70081 tttactatag attcattgta agaatctggt cttgttgtgt agccataaat ctcttgttct
    70141 agtctatttt ttaaagaatc aattatacaa ggtgcagcct taaaatccat gtcagccacc
    70201 cacataggaa gtaaatcatt agttccatac tttttttcca tttctgacca tttagatgaa
    70261 aaattattgc ttctatcaac aatctcatta aaattataat tcattgtaaa tacctccagt
    70321 aattttaatt ttatgttaat aatattaagc aaacaacgtg ccaatattga taataaaaaa
    70381 tatttattca caagttaata tttaatatta agtaatttca gagcatagat aagataaaaa
    70441 tattaattat acttaaaact ttgtggaaaa ggttatttct aataaatttt taaatatatg
    70501 aaaatgtaat taaataggtt aaataggttt aactgtttaa cttgttagac ctatttatat
    70561 tttttagaaa ctctactccc tttgatgtta taattgaacc tccacgacca acaagtatgt
    70621 ctacaagccc aaagtcttgt agttctaaaa gcatatttct aatctgttgt tctgtcaaaa
    70681 atctattttc ctctaaagct attttacata agctttttct acctattctt tcttttaaat
    70741 cataagcctt ttttaaatta tccaatataa atatgtattc atctagtgac cttttaaaat
    70801 tatagtcgta tttcatgatg tttttgtctt tgccaatgtt gaattgatac ttttttatat
    70861 tattacttac tttattacaa acggttctac tataatttga atctatagta tctaatatat
    70921 attcaggtaa atcacatatt tctataatat ctttttccaa gtaacagaaa tattctccta
    70981 agtttcttaa ttctcttaca tttccttccc atctatacat tttaaagatt tcttttactt
    71041 cctcacttag aataaaatta catggaatat catattttaa tgaaccaaaa atttcaaata
    71101 tatcagcagg tctttcccta agtggatgta ttttaagggg aagaacattc aacctaaaat
    71161 ataaatctct tctaaacata tttttagata caagttcttt taaatttcta ttagtagctg
    71221 caattattct tacatcaatg tcaatgacat tattagaacc aatacgtcgt acttgttttt
    71281 cttgtatgac tctaagtaat ttagattgag aatttaaatc catttctcca atttcgtcta
    71341 aaaatatagt tccattgttg gctaattcaa ataaaccaat tttcccacct tttttagcac
    71401 cagtaaaagc cccttcatca tagccaaata attcactttg cagtagattt tcttgaaaag
    71461 tactacaatt tactgcgaca aaaggaccat cttttctcct agaagcacta tgaatggatt
    71521 gagcaaataa ttctttacca gtaccacttt caccaattat aaggatagat gaatttgatt
    71581 gagccatttt attagcaatt ttttttgtat taatagtttg tatactagaa cctaatatat
    71641 catcaaatgt gtatttactg atattaccag agtttactag ttgtgctctt aatttagctt
    71701 gctttttttc taattgagaa aactttgtca tctttagtat aaatccatca aatacattta
    71761 attgtatatg tttaatctct aaatttatat caatatgatt tattttaatc aatttctcaa
    71821 aaaatggagt tttattggtc aatatgcttt gaaaattgat gtcttttatg caatcaccaa
    71881 caaatgagtc aatcatttca tttgcattta tagacaaaat ttttctagcc atatgattat
    71941 agaattgaat tattccatcg ttatttgtgc atataattcc atcatcaatt atagatagta
    72001 acaaatcaaa ttgtctttca aacttatttg catctaacaa taactcacct gtactataac
    72061 ttgtaggaat tattttttct acgtattttt ttattaggtc atcttttatt agatgtttta
    72121 atttggtttt tgtagcaatt tcaacaatac aacttaaatc tattattctg tattttaaat
    72181 ctataacttc acaattttta aacttaggca agattttttc gccaggagtt aggattacag
    72241 catctgtggg agtaaactca atctctggat agcagggcag gatatttata ttgtctattc
    72301 ctaatctatg tattaaagaa attgtttcta ttgccatatc tttacttaag ttatatacat
    72361 aaataatttt atctttttct aatttggata tcatatcaat actgttcttt tcaaatgtca
    72421 acttaggaac aatgatttga gcatcatagt gagataattt tactatttca tcatatttta
    72481 aataagcaga taggagtata agtttttctt taaaaaactt taaatttcct tcttcaaatg
    72541 agtataaatt tatctttaga ttatcaccta agaattgtct tatttgattt tcataaattt
    72601 ctccagcgtc tttttttaaa cttacaatag ctaattccat ttgtttcatt ttaacctctc
    72661 atacaaattt gacttatttt agattacata ataattaaat tagattaaat aatattattt
    72721 aattattatt ataaatttat tatagactac acattgaagt aaaagaagta gctaaaatta
    72781 ttccttttat ttttgttttt tgtatctatt tggtataata gtattagagc gtataataat
    72841 ttaggcaaaa ttttttaagg aagactagag gagaatataa aatgaaaaaa tgtctttact
    72901 gtaataggga tataaagtca ccaaataata aattagctat aaaatatgat gacaatatga
    72961 atatatatcc atgtcgtgca gaatgtaagg aaaaaattga agaatatata gcaaaaaaac
    73021 ctacatataa gtttataaat atattagagg ttcttttagg tgtgggcgga atattctgct
    73081 ttttgagtaa atggactatt gcagcccaag ttgtacttgg aattgatgca ctggttatat
    73141 ttttattccc attggcagga tttaagatga atggaaagtt aagtatggaa caaactaaga
    73201 atcaaagtag gtctattgca atatcaattt tggcatttat agtaataata actgtattat
    73261 attttaaaca aattggtaag tagagcataa ttgtataaga catcattaga gtatgaggtg
    73321 agtttatgga agaaagaaaa ttagcaccaa acaatgagag ggaagctctc ataaaaagat
    73381 taaaaagaat agaaggtcaa gttaagggta tacaaaagat ggtggaacaa gaacgttatt
    73441 gtgttgatat attggttcaa atatctgcta taaggtctgc tataaataga gtaggcacaa
    73501 ttatcttaga gaatcatata aaaggatgtg tagcagaaag cattaaacat gatgatgctg
    73561 ataaaactga agagatgata aaagagctta tggatactat aaataaattt acaaaataag
    73621 gaggcggtta gttatgaatc aacaaggatt tattatggaa attgttgatg atagaactgc
    73681 aaagttaaaa atgcaaagac attcagcttg tgctgcttgt ggaaaatgtg ctactacaaa
    73741 ttcagcagag tcaaaagaaa tattagtaga agtagacaac acaattggcg caaaagttgg
    73801 tgaccatgta gaagtgagta tggataatat gaatgtatta aaagcagctg taatggctta
    73861 tataatacct cttatagcac ttcttgtagg aacaataggg acttattata tattgggggc
    73921 aattggaatg acaactggag ttgaagccat aagtggatta gttggaattt gtcttacaat
    73981 aatctgttat ttatacttaa agaagaatga caaaaaattt agagacagta gagaatttat
    74041 accagtaata acaagaatat taattgacct ttaagataat tataattaaa aaatagcaat
    74101 gtgcttctta aataaatact caatacgtat ttgtagagtt taagtacatt gctattttta
    74161 tatttttatt ttgattttct gtaaggaata aagttttttc tgattttcaa aagattcaat
    74221 gttcttacaa aagaagttac aactaataca ccaagtgcta ttgcagcact tagaaatagc
    74281 gcatctgtac cttttgacat agccaaagaa taatttttct gaatcaaaga caacattgta
    74341 ttatatagcc caattcctgg tattagagga agaatacctg gaattacgaa cacaatagct
    74401 ggttgcttta gttttcttgc taaagtctca ctgcacgctg agaccaaagc agcagcgata
    74461 aaacctgcaa aaactgcatt tgtagtaaaa ttaaataaat aaacatatac aatccaacca
    74521 attccgccag ttactccagc tggaagaagt agatatagtg gagcattaaa gaaaacagca
    74581 aatccagcag ttgcaacacc tgaaaataaa aaatgcaaaa tcatagacat atcagtcatt
    74641 agaaaggacc tcctattcta taccatgtat caaggacaaa accaactcca gaagcaattg
    74701 caataataat catagcagca tcaaaagcac gagaaattcc tgatattaaa ttccctgata
    74761 ttaaatctct aatagctttt ataaaagcaa ctcctgggag tagtggcatt atagcgccga
    74821 ctataagcat tttagggtca tctaaaatgc ctatttcaac tagtagaact cctgaaagtg
    74881 caattaaaaa agaagatact aaacaggaaa atgcagatat tgcacttatc ttcatcgttt
    74941 tatcataagt aattgcagca aagattgcta ttataaacgt aagtataaaa tttaatacat
    75001 aattccctcc aagcaaacaa gcaaaacaag cagatgcaat tcctgtacaa gagtaaaata
    75061 accataaagg ataaggtttt acatcttgga tttcataaag acgtgcaatg gcattatcaa
    75121 tatcatactc tttgtcacta acaaattctc gagaaaaact gtttaataaa gaaatcttat
    75181 ttaagtttat acctcttgat tgaatcgttt tcataaacga aaagccatca aatttctcat
    75241 ctgaaataat tattactgta ggagttgtaa aaatatttac atgataaaac cctcttgacc
    75301 tgcatattct aaggacactg tcttcaaccc tagatgtttc agctccattt tttatcatca
    75361 gttcccctac aaatagagct agttttagaa tatttttctt atattcaagt tcctcatttt
    75421 gattcataaa tacacctcca aattaaaaaa cgtaatattg aaattatatc aaatttttaa
    75481 gtaatattcc ttaatatcta tacaaatata ttatcttttt tttgtttcaa aatagtcaca
    75541 tttaaattat atccaattaa aagaattaga caatattatt tattatattt taacttaaaa
    75601 ataaagaaag taactatgtt aaatatggaa aaatggcaaa acacttgact attaattggt
    75661 aaaggactat aataataaat tatcatattg ataaaaacga aaattatgaa atgtctgtaa
    75721 aaataaaatt taaataataa ctaggaggag taatatgttt gagaacttga aaaaagcgga
    75781 ccctgagatt tatgaaagta tgaaaagaga gttaaaaaga caacaaagaa atattgaatt
    75841 aatagcatct gaaaacatag tatcagttcc agtaatggaa actatgggaa gtcatcttac
    75901 aaataagtat gcagaaggtt actcaggcaa aagatattat ggtggatgtg aatacataga
    75961 tgaagttgaa actcttgcaa tagatagaat caaaaaaata tttggagcag aacatgctaa
    76021 tgttcaacct cattctggag caaatgcaaa tattggtgta tattttgcta tgttaaaacc
    76081 aggtgatgtt gttatgggaa tgaatttatc tcaaggtgga catttaactc atggtgctcc
    76141 agttaatatt tctggtcaat attataaatt ttatgaatat ggtatagata aagacagtgg
    76201 acttatagat tttgatgaag ttagaaagat agcacatgaa gtaaaaccta aaatgatagt
    76261 tgcaggagca agtgcatatc ctagagaaat agattttaaa aagtttagag agatagctga
    76321 tgaggttgga gcattgctta tggtagatat ggctcatata gcaggtcttg tggctgctgg
    76381 tcttcaccaa aatccatgtg aagtggctga ttttgttaca acaacaactc acaaaacttt
    76441 aagaggacct cgtgggggtg ttattctttg taaagaaaaa tatgctaaag acatagacaa
    76501 agcaatattc cctggtattc aaggtggacc tcttgaacat ataattgctt ctaaggcagt
    76561 ttgctttaaa gaagctttaa gtgatgagtt taaagaatat caggtacaag ttgctaaaaa
    76621 tgcaaaagcc ttagctgaag aacttattaa aagagatttt aaattgattt ctggaggtac
    76681 agataatcat ttaatactat tagatttgac taataaaaat ataactggta aagcagcaga
    76741 aaagagattg gatgatgctt atataacagc taataaaaat acaattccat ttgacccaaa
    76801 tggtgctctt gttacaagtg gaataagact tggtactcca gctgtaacta ctagaggtat
    76861 gaaagaagaa gatatggcaa taatcgctga ggctatagac ctatgtttaa cttatgatga
    76921 agaatctaag gctagaacat tggttgttgg tttaactgaa aaatatcctt tatatgaaga
    76981 atataatatt atggattaat tataaagaac aactaaataa aatacattta aataattaca
    77041 atgattgtgt atgtatttga atatatttag atataaaaaa ggtgtctcaa aatgaacttt
    77101 ttagtttatg aggcactttt ttgtatggaa tcgaacatat ttgtattatt taaataataa
    77161 aaaatatggt tatctctatt tttagatggt ctctttgtat tttttaatta aaactttaag
    77221 atttcttaag aattatacta ggtttttcta aagatttaaa gtctatactt ataagtatag
    77281 taatcatatg aaaagaaaag ctttaacgag gagggaatct tatgaaggta ttaattctta
    77341 caggaaaatt tggtatgggt cattactcag catcaaattc tttaagtgaa gatataaaag
    77401 caaaatttga taattcagaa ataataatta aagatatatt tgagtacatt atgcctaact
    77461 attcagataa aatgtacaag actttttcta ttcttgtaaa tcggggaagt agtctttata
    77521 atttgtttta taaatgtgct gaaaatggaa agaaagatat aaaatttact ttttcagatt
    77581 attttttaaa taaattagat acattacttc atgaagtaca accaacagta gttatttcaa
    77641 cttttccatt ttgttctcaa ttagtatcaa gatataagga aaaatataac tcaaatcttc
    77701 ctttaataac atgtataact gatataagta gtcactcaga atggattagt aaaaatacag
    77761 actgttattt agtagctagt aaatctacta aggaagaact tgtttttaaa ggaatagatg
    77821 aatctaagat taaagttaat ggtattccag taaaaaaaga atttaaaaga atagaacatg
    77881 taaatcattc aactaaaaaa aatattctta taatgggtgg aggattagga ttactgccta
    77941 aatcagaaca attttacaaa gaattaaata gtttagaagg agtaaaaact actgtaataa
    78001 ctggtaataa taaaaaaatg tactataaac tatatggtag atatgaaaat atagaggtag
    78061 taggttacac caatgaagta tataaatata tgaaagattc tgaccttatt atttctaagc
    78121 caggtggaat aacactattt gaaacaattt attcagaact tccaatattg gcatttaatc
    78181 catttttaca acaagagata gataatgcta gttttatatt aaataatgaa attgggagaa
    78241 tacttggtaa aaataaaaaa tactatgtag atgagataaa agatttaatt tatgatgatg
    78301 ctactcttaa agaaatgagc agtaacatga aagaattaaa aaaacaattt gataataata
    78361 ccttagagaa tattttattt tcacttgatg aacaaggagc gtgtagagaa tgtatgtagt
    78421 aggtttaatt atcgttgttg cattgatttt tttagtccat tcaattatac ctacatacta
    78481 taataaacta ttaaataaag aggtattaaa aaatatggct ggagaaaatg aaattgcact
    78541 tacatttgat gatggtccag ataagagata tacagaaaaa ttactagatg tgttaaaaga
    78601 aaatgatata caagctatgt tttttgtagt agcaaagaat gctgaaaaag agcctgaaat
    78661 tataaaaaga atgttgagag aaaatcatat agttggttta cattcattgg aacacagaaa
    78721 tgcatggctt tatagttata gttatgttaa aaaagatttt attgaaagta caaatataat
    78781 gaaaaattta ggtgtagatg taaactacta tcgtccacca tggggtcata ctaatatatt
    78841 ttcaaattca tttgttaaaa aatataatct aaaaatgact ttgtgggatg taatggcaga
    78901 agattgggag aaagatagta cagtagacat tattataaac aagttaatga gtagaacaaa
    78961 agaaaattct ataatttgtt tacatgatgc aggtgaaaat tcaggtggtg cagtaggtgc
    79021 acctgagcgt actattgaag ctttaaagat agctattcca aaacttaaag ccagtggttt
    79081 aaagttcgta acaccagaaa ggatgtagtt atgataagta aaactgaaaa gaaaaataaa
    79141 tgcctaggta gtgtagcttt tttagtttta ctaatgggca taacaggata ttttgttttt
    79201 agagggcagt cagttgaatc attgataaaa tcattaaaag gtgcaagccc tatgtttata
    79261 ctaattggat ttgcaatgat gtttatatat gttgcctgtg aaggtataaa tatatactta
    79321 ggtatgaaag ctttaaacca aaagactact cttttaaaat gtatgggata tgcttttatt
    79381 ggattttatt ttagttctat tacgccttca gcatcaggtg gtcaaccagc acaagtttat
    79441 tatatgaaaa aagacgatat aaatatatca tattcttcac ttatactatt agtcattgtt
    79501 gttattcacc aagtagttat actggcatat agtggaataa tgttcattat ggaacgtgag
    79561 tttatattaa ataatgtaag tggtatgaac attttactaa tatatggtgt aataacaaat
    79621 gttgctcttg tcattggagt aattgcaatt atattttcaa aaaaacttgt aaacaatttt
    79681 ataatatcaa taacaaattt attaggtaag ttaagaataa taaaagatgt tgaaagttca
    79741 agaaaagtta taatatctca aattgaagag tatgttaaag gtgctcaata tataaagcag
    79801 aatccaaaac ttgtagtcca aattttagtc ataactattg tacaaataac atctatgttt
    79861 ttagttcctt tctttgtata caaagctttt catctatcaa catatactgt atttgagata
    79921 ttagcgatac aatccttgct taatattgct gtttcttcat taccattgcc aggggctgtt
    79981 ggagcttctg aaaatagttt tatgacatta tttaagatat ttttccctgg tcacttatta
    80041 gttccggcaa tgttacttag taggggaata agtttttatg catttgtagc tataagtgga
    80101 ttgatatgta tagtagtaca tgtaaaatct tctgaaaaag taaaagcagt gaaaaaagtt
    80161 gcttatgtaa gataatatta tatagattat ttttattaat atgtcaattt gtgtgtatat
    80221 tttaattaag ctttaaacat gtttacagga gtagaaacta ttaaaacgtg tgacattgct
    80281 aagcttttgc taataaagta taatatttta tatagtttga aatatttaag aaatatagca
    80341 aaaaaaggag cttggtgatg aataaagaga ttccaaaaaa aattttagta gctgatgata
    80401 atcctgagat tagggaaatc gtagaaatac ttttaactgg tgaaggttat gaagttatta
    80461 tggcaacgaa tggagaagaa gctgtaaact tagtagatag tacgattgat ttgattattt
    80521 tggatgttgt aatgcctgta aaaacaggat ttgttgcatg taatgaaatt agagaaaaaa
    80581 cgacagcacc aatattattt ttaactgcaa aaactcaaga ctctgataaa gttattggat
    80641 tttcagcagg aggagatgac tatttatcaa agcctttttc atattctgaa ctaatttcaa
    80701 gggttaagtc gctacttaga cgttattata tataccaggg aaaggaaaag gaaagagagc
    80761 caaatatatt aaaaacaaaa gagttatgtg tcaatttaga tactcaagat gttacactaa
    80821 atggagaacc tgtgtttttg acaactatag aatatagtat attaattctt atgttgaaaa
    80881 atagaaaaaa agttttttcg tctgaaaatt tatatgaaac tatttgggat gagcagtatt
    80941 tttatacagc aaataataca ataatggttc atattagaaa tttaagaaaa aagttagaaa
    81001 aagaccaaaa aaatccacaa tatataaaaa ccgcatgggg aaaggggtat tatattgatt
    81061 aacaaaatta agccatctaa gttgggagtt atactattga tatatgtagt aatctcagct
    81121 gcagtggctt tcattttaaa tataccattt tactctgctg ttgaatctat agtaaaagat
    81181 gtatcagaag ggaaagtata ttttaaaaga gaagtaaatc aacttatgga taattttcaa
    81241 acttatgtga ataacaatgg tataagagca gatgatggag atgatatagc aaaatggaat
    81301 agtgataatt ggtttgtttc tatgaagata tataaaggaa ataaggtttt ttatgataca
    81361 ttatactatc ctaatgaagt acctgataag agtgaggaaa atgagtttta tagcagtccc
    81421 atggctagaa actatgagat acaattttct gatattaaag ctaatatagt tgtagtagct
    81481 ttatttagat ttagatttca aaattttata gaagcaattt ctattacatt tatggcactt
    81541 acatttatta taacattttt actgttgttt agtagaaaga taaagtacct aaggaaaata
    81601 gaaatgggta taaagatagt agagagtggc agtttaaagt atagaatccc agtaaaaggt
    81661 aatgatgaat tatcatcact tgcatctagt attaatgaga tgagtcatac attggagaat
    81721 caacttataa aagaaaggga gatgaagaat aaaaataaag atatagtaac ttcgatatca
    81781 catgatgtta gaactccatt aacgtcagta atttgttatt tagatttgat taaagaccat
    81841 aaatacaata gtcctgagca attggaacaa tacataaaaa atgtaaggtc taaagcatat
    81901 caaataaaag atttaacaga tgaccttttt acgcattttg ttaattctgg agaggaagtt
    81961 tcaaaagggt atgaaaaaat aaatgctaat gaatttattt ttcaattact tttagatagt
    82021 tcatatacat tggaggagaa aggatttcat ataacaatag aaaatgaact ttataaccaa
    82081 tatcatattt atgtagatgt tacacaattt agaaggatat ttgataattt atgttctaat
    82141 ataataaaat atgctaggaa agataagcct atagtatttt taattaaagt agaggattct
    82201 aaattactaa ttatacaaaa aaatagagta agtaattttt ctaagaatgt agaaagtttt
    82261 ggaattggta taaagaattg tgagaaaata gttgcatatc ataatggaag cataaatgta
    82321 aattcagatg ataaagaatt tgctattgaa atatctattc cagcaaaaga atcataaaaa
    82381 tttaaattat atattgtgta attgctatta tatattgtgt aattgcttat gtaaaattct
    82441 atgaagcagg aagcatgtga ctttagttat gggatgttca atattgtgta cctctaggca
    82501 agtaacaagt ttacttacaa gaccatataa tattattatc ttaaaaaaag gggacataat
    82561 aatatggttt tgacaggagc acattatatt tacattctat ttatggtaat tatattaatt
    82621 actatgatta tgaaaaagga tacaatagta ccatgtatat taggtgtttt ttttatggga
    82681 ttgttctttg aaaaaaacat ctttggtgct ataacagcag tgtttaactc ttttattata
    82741 tctttaaatg agttgggtcc aattatcttg attatagcta ttatggttgc attatctaaa
    82801 gccctagaag ccaataatgc tatacagtat atggtgagac cattttcgag agttataaaa
    82861 aattctaata cagcattttt tgtaactgga tttgttatgt tagttctttc ttggtttttc
    82921 tggccaactc cagctgttgc cttagttgga gctgtatttt tacctgttgc tatgagagct
    82981 gggctaccag caattggtgt tgcagtagca ttaaatttat ttggtcatgg tcttgcctta
    83041 tctacagact ttgttattca aggagctcca agtataacag ctggtgcagc aggtgttgca
    83101 gtatcatatg ttataaatga tggtatgatt ttgttttggg tgatgggaat cgtaaccata
    83161 tctatggcat tttatacatt aaaaagagat attaacaaag gaatgtttag agaagaacta
    83221 aaaggttttg aaagtgaaga agtagaagcg ttcaatggaa aatctaaaat agcaactatt
    83281 ttagtagctt tgggatttct tgctgatata attgctatgt atgtatttga cctaaaagga
    83341 ggagatgcat cagctctttt gggtggaaca gcagtatttt taataataat tataaatgtt
    83401 ataaattttg gcaaagatag tcttgaaaat gtatgtgaga atataattga tggttttgtg
    83461 tttgggataa aaatatttgg agcaattata ccaatagcag catttttcta tatgggtgaa
    83521 gttgcaccat tgacaggtgt atttggaaaa gtattagcac caggttcaca aggtttatta
    83581 tcagatatag gcatagctct ttctcaaaca ataccactta ataaatttgc cgtatcaggt
    83641 atagaaactg tagtgggagc aataactggg cttgatggtt ctggattttc tgggatttca
    83701 ttagttggtt cacttgcctc tgtatttgga actgctataa atgcaagtgt tggtgcatta
    83761 gctgcattag gacaaatcag tggtatatgg gtaggtggag gctgtctagt tccttggggt
    83821 cttatttcag cagcggcaat ttgtggggtt agtccaatag aattggcaaa gcgaaacttt
    83881 gtcccagtta taaccggatt ggttgtaaca accatagtag caatgtttat tatttaataa
    83941 atcgaataaa tctttaattg tataaattaa aaatagatgt gtagctataa tttattataa
    84001 ttgttttact aattctaagc catacatcta tttttattga tatttttatt agtattcttt
    84061 aataaagtaa tatttttcat tatattatac ataacatcta aatataacat ctaaaatact
    84121 gttatctata tttaatatct tgccaaattt tttgatgttt tattgccctg tcccaccaac
    84181 atatataagc tatcacaagt ttttacctat actatcacca aacaaaaatt ctaattttaa
    84241 tttattattt tataacctat attatattaa ctatattagt ttgtagactt tagatgtaat
    84301 tataaatatt aatactccaa gagttcaaat tcatatccta gttttcttgc atttgatata
    84361 aaatcattta aaatttctgt actagttttg gaaactgcat gtagtaacaa gatagaacca
    84421 tcatgtagat tatccattat tttttgcgtt gcttcttcat gtgatggttg tttatcagta
    84481 tcccagtctc tgtatgcaaa actccaaaat acagtcttgt atcctaaatt tttagtcatt
    84541 gccaagcttt tttctgagta ttttcccata ggaggtctaa aaaatttaac catatctttc
    84601 ccagttacat ctttatataa cttttcaaca tcatataatt cgtcattaaa gttttttaga
    84661 ttgcttgttt ttgttggcat agatggatgg gttttactat gatttccaac tatatgtccc
    84721 tcagaaacca ttctttttac taaatcttta ttttctttta tatatggagc tgtaacaaaa
    84781 aaaactgctt taacctggtt ttgttttaga gtgtcgagta tttttgtagt gtatccattt
    84841 tcataacctt catcaaatgt aagatatagt gttttttgac catcttttgt aggtccattg
    84901 tatagggcat catagtcaga aaatttaaat tcaatgtccg tatttacttc tggtgtttta
    84961 tgcttattgt ttggtatata aaaccaatca agagtagtgt tatctaaaga agatacatct
    85021 aatttattat tatcattatt agtagtggct tttgatggtt tatctgttcc gtctgaaact
    85081 attacattgg aagtatcttt accactatct attttttcct tatcttcttg taactgtgtt
    85141 tccttatttt gattttcgtt ttgattgttt tgtgaatttg aacatccaac aataaaaaaa
    85201 atagaaatag aaagtagtgt taaataatgc aatacttttc taaacatttt gaagctcctt
    85261 tctaaattaa taataattgc atataataat aattatatga ttaattacaa ttgcatatag
    85321 tattattata attggaaatt actattaata atagttatat ctttaaaaat aaagtcacaa
    85381 tagtatgaca aagggtgaat aatcaataaa tttaaaaaaa aatgaaaaaa atagttgacc
    85441 atattatgag aagatgttat tataataaat gtgctcaaca agaagtaaca aaataacaag
    85501 cacaaagaag ttaattgaat
//
LOCUS       DAGQVA010000006        81025 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.006, whole genome shotgun sequence.
ACCESSION   DAGQVA010000006 DAGQVA010000000
VERSION     DAGQVA010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81025
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.006"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            374..3028
                     /gene="adhE"
                     /locus_tag="MIV85_000520"
                     /gene_synonym="adhC"
     CDS             374..3028
                     /gene="adhE"
                     /locus_tag="MIV85_000520"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBY2959896.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3304..5523
                     /locus_tag="MIV85_000521"
     CDS             3304..5523
                     /locus_tag="MIV85_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2959897.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            5777..6439
                     /locus_tag="MIV85_000522"
     CDS             5777..6439
                     /locus_tag="MIV85_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBY2959898.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6810..8219
                     /locus_tag="MIV85_000523"
     CDS             6810..8219
                     /locus_tag="MIV85_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBY2959899.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8334..8609
                     /locus_tag="MIV85_000524"
     CDS             8334..8609
                     /locus_tag="MIV85_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBY2959900.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            9239..9550
                     /locus_tag="MIV85_000525"
     CDS             9239..9550
                     /locus_tag="MIV85_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959901.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            9552..11477
                     /locus_tag="MIV85_000526"
     CDS             9552..11477
                     /locus_tag="MIV85_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBY2959902.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            11480..11971
                     /locus_tag="MIV85_000527"
     CDS             11480..11971
                     /locus_tag="MIV85_000527"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBY2959903.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            12023..12586
                     /locus_tag="MIV85_000528"
     CDS             12023..12586
                     /locus_tag="MIV85_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBY2959904.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            12601..13578
                     /locus_tag="MIV85_000529"
     CDS             12601..13578
                     /locus_tag="MIV85_000529"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBY2959905.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            13565..13888
                     /locus_tag="MIV85_000530"
     CDS             13565..13888
                     /locus_tag="MIV85_000530"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBY2959906.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            14005..15783
                     /locus_tag="MIV85_000531"
     CDS             14005..15783
                     /locus_tag="MIV85_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBY2959907.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            15780..17153
                     /locus_tag="MIV85_000532"
     CDS             15780..17153
                     /locus_tag="MIV85_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBY2959908.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            17159..17827
                     /locus_tag="MIV85_000533"
     CDS             17159..17827
                     /locus_tag="MIV85_000533"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBY2959909.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            18104..19153
                     /locus_tag="MIV85_000534"
     CDS             18104..19153
                     /locus_tag="MIV85_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2959910.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            19249..20238
                     /locus_tag="MIV85_000535"
     CDS             19249..20238
                     /locus_tag="MIV85_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2959911.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            20243..21961
                     /locus_tag="MIV85_000536"
     CDS             20243..21961
                     /locus_tag="MIV85_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBY2959912.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(22043..23197)
                     /locus_tag="MIV85_000537"
     CDS             complement(22043..23197)
                     /locus_tag="MIV85_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2959913.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            23696..25057
                     /locus_tag="MIV85_000538"
     CDS             23696..25057
                     /locus_tag="MIV85_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2959914.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            25148..25852
                     /locus_tag="MIV85_000539"
     CDS             25148..25852
                     /locus_tag="MIV85_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2959915.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCEYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            26052..26363
                     /locus_tag="MIV85_000540"
     CDS             26052..26363
                     /locus_tag="MIV85_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2959916.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            26385..27698
                     /locus_tag="MIV85_000541"
     CDS             26385..27698
                     /locus_tag="MIV85_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2959917.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            27795..29105
                     /locus_tag="MIV85_000542"
     CDS             27795..29105
                     /locus_tag="MIV85_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBY2959918.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            29131..29862
                     /gene="chbG"
                     /locus_tag="MIV85_000543"
     CDS             29131..29862
                     /gene="chbG"
                     /locus_tag="MIV85_000543"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBY2959919.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            29875..30192
                     /locus_tag="MIV85_000544"
     CDS             29875..30192
                     /locus_tag="MIV85_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBY2959920.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(30304..30768)
                     /locus_tag="MIV85_000545"
     CDS             complement(30304..30768)
                     /locus_tag="MIV85_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959921.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILDGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            31038..31976
                     /locus_tag="MIV85_000546"
     CDS             31038..31976
                     /locus_tag="MIV85_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2959922.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEDKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            32104..33117
                     /locus_tag="MIV85_000547"
     CDS             32104..33117
                     /locus_tag="MIV85_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBY2959923.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTKFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            33123..34145
                     /locus_tag="MIV85_000548"
     CDS             33123..34145
                     /locus_tag="MIV85_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBY2959924.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            34160..34942
                     /locus_tag="MIV85_000549"
     CDS             34160..34942
                     /locus_tag="MIV85_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2959925.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            34954..36294
                     /locus_tag="MIV85_000550"
     CDS             34954..36294
                     /locus_tag="MIV85_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2959926.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEEILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(36389..38668)
                     /locus_tag="MIV85_000551"
     CDS             complement(36389..38668)
                     /locus_tag="MIV85_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2959927.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVVAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVMNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(39005..40168)
                     /locus_tag="MIV85_000552"
     CDS             complement(39005..40168)
                     /locus_tag="MIV85_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBY2959928.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGSAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKTESLGHREFGIYRISSTF"
     gene            complement(40181..40456)
                     /locus_tag="MIV85_000553"
     CDS             complement(40181..40456)
                     /locus_tag="MIV85_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBY2959929.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            complement(40477..41451)
                     /locus_tag="MIV85_000554"
     CDS             complement(40477..41451)
                     /locus_tag="MIV85_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBY2959930.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            complement(41722..43635)
                     /locus_tag="MIV85_000555"
     CDS             complement(41722..43635)
                     /locus_tag="MIV85_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2959931.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            complement(43812..45026)
                     /locus_tag="MIV85_000556"
     CDS             complement(43812..45026)
                     /locus_tag="MIV85_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBY2959932.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            45270..46652
                     /locus_tag="MIV85_000557"
     CDS             45270..46652
                     /locus_tag="MIV85_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBY2959933.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRVRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDKPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            46664..48013
                     /locus_tag="MIV85_000558"
     CDS             46664..48013
                     /locus_tag="MIV85_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBY2959934.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            48163..48696
                     /locus_tag="MIV85_000559"
     CDS             48163..48696
                     /locus_tag="MIV85_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBY2959935.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            48780..49589
                     /locus_tag="MIV85_000560"
     CDS             48780..49589
                     /locus_tag="MIV85_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2959936.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            50000..52045
                     /locus_tag="MIV85_000561"
     CDS             50000..52045
                     /locus_tag="MIV85_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2959937.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKYFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            52306..53505
                     /locus_tag="MIV85_000562"
     CDS             52306..53505
                     /locus_tag="MIV85_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBY2959938.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARNLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            53557..54252
                     /locus_tag="MIV85_000563"
     CDS             53557..54252
                     /locus_tag="MIV85_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBY2959939.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            54265..54942
                     /locus_tag="MIV85_000564"
     CDS             54265..54942
                     /locus_tag="MIV85_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959940.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            55053..56654
                     /locus_tag="MIV85_000565"
     CDS             55053..56654
                     /locus_tag="MIV85_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBY2959941.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTAINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGINGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            57118..58407
                     /locus_tag="MIV85_000566"
     CDS             57118..58407
                     /locus_tag="MIV85_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBY2959942.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            58436..59116
                     /locus_tag="MIV85_000567"
     CDS             58436..59116
                     /locus_tag="MIV85_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBY2959943.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            59217..59756
                     /locus_tag="MIV85_000568"
     CDS             59217..59756
                     /locus_tag="MIV85_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBY2959944.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYRLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            59932..60951
                     /locus_tag="MIV85_000569"
     CDS             59932..60951
                     /locus_tag="MIV85_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBY2959945.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            61239..62429
                     /gene="dltD"
                     /locus_tag="MIV85_000570"
     CDS             61239..62429
                     /gene="dltD"
                     /locus_tag="MIV85_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBY2959946.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            62550..64064
                     /locus_tag="MIV85_000571"
     CDS             62550..64064
                     /locus_tag="MIV85_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBY2959947.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            64064..65212
                     /gene="dltB"
                     /locus_tag="MIV85_000572"
     CDS             64064..65212
                     /gene="dltB"
                     /locus_tag="MIV85_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBY2959948.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            65231..65461
                     /gene="dltC"
                     /locus_tag="MIV85_000573"
     CDS             65231..65461
                     /gene="dltC"
                     /locus_tag="MIV85_000573"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBY2959949.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            65678..66463
                     /locus_tag="MIV85_000574"
     CDS             65678..66463
                     /locus_tag="MIV85_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBY2959950.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKHSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            66742..68652
                     /gene="phnW"
                     /locus_tag="MIV85_000575"
     CDS             66742..68652
                     /gene="phnW"
                     /locus_tag="MIV85_000575"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBY2959951.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPTEDDVNELYAEFETMLFETLE
                     DYTTPIPHVVETIEKLRENGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEELSKCKGIAKSLSLDVYAQWDTMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            69011..69832
                     /locus_tag="MIV85_000576"
     CDS             69011..69832
                     /locus_tag="MIV85_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2959952.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            69873..70640
                     /locus_tag="MIV85_000577"
     CDS             69873..70640
                     /locus_tag="MIV85_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBY2959953.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            70648..71268
                     /locus_tag="MIV85_000578"
     CDS             70648..71268
                     /locus_tag="MIV85_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBY2959954.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(71568..72155)
                     /locus_tag="MIV85_000579"
     CDS             complement(71568..72155)
                     /locus_tag="MIV85_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBY2959955.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(72241..72678)
                     /locus_tag="MIV85_000580"
     CDS             complement(72241..72678)
                     /locus_tag="MIV85_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2959956.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            72782..73780
                     /locus_tag="MIV85_000581"
     CDS             72782..73780
                     /locus_tag="MIV85_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBY2959957.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(73900..74826)
                     /locus_tag="MIV85_000582"
     CDS             complement(73900..74826)
                     /locus_tag="MIV85_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBY2959958.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            75212..76816
                     /locus_tag="MIV85_000583"
     CDS             75212..76816
                     /locus_tag="MIV85_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2959959.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVVDNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            77632..78903
                     /gene="serS"
                     /locus_tag="MIV85_000584"
     CDS             77632..78903
                     /gene="serS"
                     /locus_tag="MIV85_000584"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBY2959960.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKTEYVHTLNGSGLAIGRS
                     VAVILENYQQEDGSVVVPEVLRAYMGVSVIK"
     gene            79274..80779
                     /locus_tag="MIV85_000585"
     CDS             79274..80779
                     /locus_tag="MIV85_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBY2959961.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTIPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTVKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            80893..>81025
                     /locus_tag="MIV85_000586"
     CDS             80893..>81025
                     /locus_tag="MIV85_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator"
                     /protein_id="HBY2959962.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     "
BASE COUNT        30854 a         9278 c        14072 g        26821 t
ORIGIN      
        1 actatattta ctttaacttg ttaattaagt tttaattttc attttcaagg atttttattt
       61 ttaaacttga tagagtatca tattaaaaat tctttttata aagttttatt tgcaaaaaat
      121 acaaaaatat aaacgttaaa aaaataacgt tatccttaag tttttagatg atttcattag
      181 tgatttgcgt aaaaaataaa gtgatatcta gttaaattaa gtatttgtaa agctagatat
      241 tattagtaga aatgatgtta tattagataa aaaataaaat gttaaaaaaa taacttgaaa
      301 ataggaaaag taaatgctat aatgttaata aattaacata ataaataaaa aactatctca
      361 ggaggttgtt aaaatggctc ataaagaaca agtaataata gaaaataaaa aagaaaatga
      421 agttatgtca gttggtttag atactgtaaa taacgttgaa agcttagtta aaaaactagc
      481 aaaaatcaga gaagctcaaa aaatatttgc tacatatagt caagagcagg tagataaaat
      541 ttttttagca gcatctttgg cagctaataa gcaaagagtt cctctagcta taatggcaca
      601 aaaagaaact ggtatgggaa ttgctgaaga taaggttata aagaatcatt atgcctcaga
      661 gtatatatat aatgcatata aagaaactaa aacttgtggt gttatagaga aagacgaagc
      721 atttggtatg actaaaattg ctgaaccaat aggtgttatt gcagcagttg tacctacaac
      781 taatccaact tctactgcta tctttaaagc acttttagct ttaaaaacta gaaatggaat
      841 aattttctct ccacatccaa gagcaaaaaa ttctactata gaggctgcaa aagttgttct
      901 tgaggctgct gttttagctg gagctcctga aggtataata ggatggatag atgagccatc
      961 tttagaatta actacaactg ttatgaaaga agtggatttg acccttgcta caggaggtcc
     1021 tggaatggtt aaatcagcat attcatctgg aaaaccagct attggagttg gtgcaggtaa
     1081 tactccagca ataattgatg atagtgcaga tataaaaact gctgtaaact caattcttgt
     1141 atctaagact tttgacaatg gtatgatatg tgcttctgaa caatcggtta tagtattaga
     1201 aaatatatac aatgaagtca aaaaagaatt taaagagcgt ggtgcttatt tattagataa
     1261 agatgaaaca gaaaaaataa gaaatataat tttagtaaat ggaggattaa attctaaaat
     1321 agttgggcaa acagcttgta ctatagcaaa acttgcaggc tttgaagtcc cagtagatac
     1381 taaggtttta ataggtgaag tagaatcagt tgaaatagaa gaagcttttg ctcatgagaa
     1441 actttcacca gtacttgcaa tgtacaaggc aagtgatttt gatgatgcag ttagaaaagc
     1501 agaaaaatta gtagaagatg gtggatttgg gcatacatct tcattatata ttgatgatgt
     1561 aaatcaaaga gaaaaacttg ataagtttac ttcagccatg aaaacttgta gaattttaat
     1621 taatactcct tcttctcaag gtggtatagg ggacttatat aattttaaac tagctccttc
     1681 tcttacttta ggatgtgggt cttggggtgg aaattcagta tctgaaaatg taggagttaa
     1741 gcatttactt aatattaaaa cagtagctga gaggagagaa aatatgcttt ggtttagagc
     1801 accagaaaaa gtttatttca aaaaaggttg tttaggagta gcattaaaag aacttaaaga
     1861 tgtaatgaat aagaagagag cttttattgt aacagataca ttcctttaca ataatggata
     1921 tactaaagca gttactgatt tattagatga aatgaatatt aagtacacta cattctttga
     1981 agtagaacca gacccaactt tggaatgtgc taagataggc gctaaagcta tgagagaatt
     2041 taatccagat gtaataatat ctataggtgg aggaagtgca atggatgcag gaaagataat
     2101 gtggacattg tatgagcatc cagatgtaga tttccaagac ctagctatga gatttatgga
     2161 tataagaaaa agggtatata cattccctaa aatgggtgaa aaagctaatt ttgtagctat
     2221 accaacatca gcaggtactg gttcagaagt aacaccattt gctgttataa ctgaccaaga
     2281 tacaggagta aaatatccat tagcagatta tgaactgatg ccaaatatgg ctatagttga
     2341 ttctgatatg atgatgaata tgccaaaaag cttaacatct gcttctggta tagatgcttt
     2401 aactcatgca ttagaagcat atgtatctat gcttgcaacc gattatacaa atggattagc
     2461 tttacaagct attaagagta tatttgaata tcttccacgt gcatatgata atggtgcaaa
     2521 agacccagaa gctagagaaa aaatggcaaa tgcttctaca atggcaggta tggcttttgc
     2581 aaatgcattt ttgggtgttt gtcactctat ggctcataaa ttaggtgctt tccaccatgt
     2641 accacatggt gttgcaaatg ctcttttgat aacagaagtt atgaaattta attcttcaga
     2701 tgcaccaaag aaaatgggag cattctctca atataaatat ccagaagcat taaagagata
     2761 tgctgaaata gcttcatttt taggattaaa aggaaattct gatgaagaga aattccaaag
     2821 tttattggta gctattgaag atttaaaact taaagttggt attcctaaat ctataaaaga
     2881 gtttggcgtt gaagaatcta agtttatgga ttcaatagat gaaatggtaa ttcaagcatt
     2941 tgatgaccaa tgtacaggag caaatccaag atatccactt atgaatgaaa taaaagatat
     3001 gtatttaaat tcatattatg gaagataagt ttgctataaa atagataaaa taaaaactct
     3061 tatacataaa acaaagtttt attgtataag agtttttttg tttgagaaaa tggatagttt
     3121 ttattcttta atttaaaatt caattaaata gtgttattat aataataaaa gaatgttttt
     3181 atggttatta tgttgatttt atgtgtaaca tttaagaata gttatataca atataaatga
     3241 tgaattggta taaaaaggat atattatcta tatgaagtat tgactaatta ggggaggagt
     3301 cgaatgacag ggagaaataa aagttttaca ttaattacaa ttcttttttt aacatcatta
     3361 tttttgacaa tggggtatat ctatatagaa gatacaaaac atcttcttat gtcagaggca
     3421 aaaatacata taaaagaagt tgcagtacaa ggctctcaac tagcacaaag acaaattgaa
     3481 aaagatttag atgttttaaa tattttttct aactattatg cttcaaatcc agatatacct
     3541 aatgaggaaa aaatgaaaaa tcttttagat gaaatggaaa atcaaaaatt ttacactatg
     3601 gcaatagttg atataaatgg taatgctgaa aataccaaag gtgataagtt ttcagtgaaa
     3661 gatagagaat ttttcaaaaa ctcaattaaa ggtaagaagt atgtttcaag tccatatgtt
     3721 gatgaagtaa ataagtctat aaagaagatt gctatttcag taccattatt aaataatgat
     3781 aaagtagttg gagttttata ttgtacttac aatatcaata ctctgatgaa acttattaat
     3841 atatcttttt atgaaaataa tagtatatct tatgttgtaa aaaatgatgg tacaattatc
     3901 cttcatccac aaggggatag cctatcaaaa aatatttata aattgttaga acaggataat
     3961 gatattcaag aagtaaatag attaaaaaaa gaattgcaag aaaataaaac aggtgcaact
     4021 gtattaaata tgttggaaga aagaagatat ttagggtatg ccactatgga taatgggaat
     4081 agtgaaaata attatataaa agactggaat ttaatttttt caattccaga aactgttgta
     4141 tttagtaatt caaaacaaat aatcaacaga gctgtatatg cagtgttatc tattgtatta
     4201 atatttgttg caattatttt ttatataatt tatataaaaa aatctaatga aaaagaaata
     4261 ttaagtttgg cttatgaaga taaagttaca tatataggaa atcaaaataa attttataga
     4321 gaatgtagta agtatctttt agataaacca tctttaaatt atattatagt atattttgat
     4381 attaataact ttaagatgat taatgatact tttggatatg aatttggtga caatttatta
     4441 attacaatag caaaagcttt aaaagaagaa ttaacagaag gtgaggtata tgcacgactt
     4501 tcaagtgatt attttgcaat tttctgtgat tataaaaatg gaagaaataa aattataaga
     4561 aaacttgata atatacgaag taatattgaa agtaatttga gtatagtctt tgaaatttct
     4621 ctgtgtgtgg gtatttattt tgttgaagaa ggtgaagtag atattcaaaa ggctgtaaat
     4681 aaagcaaata tggctaggtc tgttgctaaa ggtaaaaata taaattatgc tatttataat
     4741 gaagatgtta ggaataagct tagtgaggaa tcaatgattt tagacgatat aaaaatagca
     4801 ttggtaaaaa atcaatttga agtgtattat caacctaagt tttcacttgt aactggagaa
     4861 atgataggga gtgaagcact aataagatgg aatcatccag aacatggttt tataagtccc
     4921 gcagtattta ttccaatagc agagaaaagt aagttgattt taaaaattgg gagatttgta
     4981 tttgaaaggg tttgcaatga tttatatgaa tggaaaaagc aaggtaaaaa gatagttcca
     5041 gtttcagtaa atttatctag ggtcgagttg tatcaaccag atattgtaaa atttatcaat
     5101 aaaacaataa aaatgtataa tttaagttca gatttcattg aaatagagat aacagaaact
     5161 gtggctatta atgagttaaa tattttaaag aatgttttaa atgagttgag gacgtatgga
     5221 ttttctattt ctatggatga ctttggtaca ggatattctt ctattagttg tttaagagat
     5281 atgccaattg atatattgaa gctagataag tcttttcttg gtggcattga acatgatgag
     5341 agaagtcgca atatagcaaa atcaatagtg tctctagcaa aatcactaga tttagttgta
     5401 attatagaag gtgttgagag taaagaacaa gctgagttaa tgaaacaatt tggatgtgat
     5461 ttagttcaag gattttattt tgcacgacca atgccagcta agaatttttt agatttactt
     5521 taaaacaaaa tttgattttt atataaagca ctattatgaa tgcttgattt taataaatca
     5581 ttgctaaata attagtgttt ttttatttta tcaatgtatt gtctaatata aagcaaaaaa
     5641 taattgtatt ttataaaaat tatattaaaa ataaatttat tttgctaata aacatgttat
     5701 taacaaaaga atagtactat aatgtataga tgataaaaac tttaataaaa atttagtgta
     5761 taggagttgt ttaagtatga tagatataag tattgatgac aaacttaagg aaagatggcc
     5821 taatgctaag ctgggttgca ttcaagcaaa agtagcagta aataaaagct cagaaaaatt
     5881 aattaatgaa ataaatgagt tttgtgatac tataaatcaa agtctaaaag ttgaagacat
     5941 tacgaaacta gataaaatta aagatgcaag aaatgcttat aaagagcttg gaaaaaatcc
     6001 aagtagatat agaacatctt cagaagcatt ggttagaaga attattcaag ggaagggtct
     6061 ttatacaata aataatatag tagaaataaa caatttaata tcaataaaat cattatatcc
     6121 agtaggtaca tataatgtaa gcaaattaca ttcaccagta tgttttactg taggagatga
     6181 aggagaacag tataagggta ttgggaaaga attaataaat atagaaaatc ttcctatatt
     6241 gtctgattca gtgggtaaat ttgggagtcc aactagtgat tctgaaagag caatgataac
     6301 agaagatgca aatgaaatat taatttgtat attttctttt agtcaagaat ctgatattga
     6361 agaatatttt ggatatgcta aggaattact taaagaatat gcagatggaa aagatataga
     6421 aactaaaata attaaataga atctatataa caacgttatg ttaagctaaa attcaatata
     6481 aaaataagtt aagataaaga aactaacaca aaattagttt cttttttaaa atagtagttt
     6541 agtgttacaa aaatagatag atagtcccac gattattaaa agtatggtaa tatattaata
     6601 tagcagagat tgtgtttaag ggattttgaa aggggggatt tataataatc attttatcta
     6661 aaagataaaa tggttttata gaaataacta tatatttaaa aatataaata atgatacagt
     6721 aatttgggta tataaaataa ggcatacatg gttttgttta aaaaccaata aggtacatag
     6781 gtaattacaa tgtaaggaag gatttaatta tgattgatgg aaaagaggta aaacaagaaa
     6841 gtggacaaaa aaatctaaaa tttaagatag ctatagtagt aggtgttttg tttgtagctt
     6901 atataggaat ggcaatcttt tttagaaatc atttttactt tggaacgact attaatggcg
     6961 taaaggcttc aggaaaaaca gttgagcaag taaatgattt gttagcatct agtactaatt
     7021 cctatacttt aaacttagag gaaagaaaca ataagaaaga acaaataaaa gcaaaagata
     7081 ttgatttaaa atttacacca gatgataaag ttcaaaagat aaaagatagt cagagcgcta
     7141 ttggatggat tggtggaata tttaaatcta aagagtataa taatatgata actctttcat
     7201 ataataaaga tttactagaa aaaaggttta atgctttatc ttgttttgat agtaaaaatg
     7261 ttgtagaacc taagagtgct tatcctaagt atgatagcac taaaaacgct tatgttatag
     7321 taccagaggt acttggaaac aaagtgaaaa aagatgattt ttataagtta gtacaaaact
     7381 caattaattc tgggaatact tctatttctc tggatgaaag taaagtttat gaagcaccaa
     7441 acaacacaaa ggattcagaa aagttgaaac aagctattaa gacattagat aagtatgttg
     7501 gtgtagtcgt tacatatgat tttagtgacc gtaaggaaac tttagatggt tctgaaatta
     7561 ataaatggtt aaaagtagac tcagaaaaga attatgacat aacttttgat aatgatgcta
     7621 tggtagaata tacaagaggt ttaagtaaaa aatacagtac ttttggtgac tcaagaccat
     7681 ttaaaactgc cacaggtaaa gatattacaa tttcaggtgg aatttatggt tggttgatag
     7741 ataaaaagaa agaagctgaa gcattagttg atgttgtaaa agctggtaaa aatgttacaa
     7801 gagaacctat ttacatacaa aaagctgtat ctcgtaataa agatgatatt ggaaatacat
     7861 atgtagagat tagtctttct ggccaacata tgtggttctt taaaaatgga gaaatgcttg
     7921 tatcaacaga cgttgtaaca ggtgatttag ctagaggatt tgctacacca tcaggtatat
     7981 atcctcttaa ttataaggct agaaatgttt cattaactgg tcaaggttac agttcacctg
     8041 taagttattg gcttccattt aatgggaaca taggcattca tgatgctact tggagaaatt
     8101 cttttggtgg aagtatatat aagtcttcag gttcacatgg atgtgtaaat acaccttttt
     8161 ctaaggcaaa gaaaatatat gaaaatatag aaccaggtac accaattatt ttatactagt
     8221 aaatgtgttg ctaacagtta agcgaagtca tcttagttta tttaggatgg cttccttttt
     8281 atataaagct tattgaagtt tacagaaaga ctacttaaaa ggagaaatac ataatgaatg
     8341 aaaaattaac taaaatttta gaagaagcta agaatgatga tgaatttaga aaggaactta
     8401 taaaaacaag agaacaacgt gatgttatgg attcattttg taaggttgtt acatctagag
     8461 gttatgatat gacagtaggg gaactttttt ctatgggaga agaatataca tccaatctac
     8521 tgaaaagtgt aaatggagga gcagcatatc ctattgaaga ttggagtgat tggtacgagg
     8581 atttttttat aatgttgtcg aatatataga gtaactaatg atattatcta cttaagatta
     8641 atacattgcc ttaaaataaa actattagaa ctaggtgtaa gttttatcaa tctttaaaaa
     8701 tattgattta tttctaacta gatataaaaa aattagatta aaaataaggt gacaaaaatc
     8761 gatatagctt gatgatttat aaaagttaga taaaatagtg cgagatattt ctaaaaattc
     8821 aaaaaaaaca ataaacttca atggttagag gttgaaaaag aatataaaaa acttttatat
     8881 gtaataaatt aaattaaaat tataaaaaaa ataaaataaa aatttaaaat gtcgacataa
     8941 cgttaatttt aaaacaaaat aacgctattg acaaactata tcgctttaaa ttataattat
     9001 tgaaaataat ggtatttaaa aaccatactc atgtcatagt ctaaaagtaa gtcaaaaaag
     9061 gatgtaaatc taggcaagta ctattctaaa atatgtttta ttaagaaata aacgttgaaa
     9121 aatattaatt attatataaa aatgctgttt atactttaac aatgaggtag taatctaatt
     9181 agaataaaaa aatctaattg gttatataca tagtaaaaag gtaagagagg tgatttggat
     9241 ggcttttgaa ataataaaaa gcattgttga ggcagagcag acagcagaca gtatcaaagt
     9301 aaaagctgtt actgatgcag agtctatcag agctgatgct gtaaacaaat gtgaaagcat
     9361 atttgctgat gtaaaaaaac aagcaaagct tatggaagaa actcttattg agaaggcagt
     9421 caccgacagt agagcagagg ttgataaaat cttagctaat gctaaaagtg aatgtctgaa
     9481 aattgaaaaa actgctgaag aaagaaaaag taaggctatt gaagcggtta ttggaaaggt
     9541 agtgagataa tatggcaata gttaatatga acaaaatatc tattgttggc ttagaagctc
     9601 aaaaaagcca gattttaaag ctacttatga accgtgggtt tgttcagatt gatgatagtg
     9661 cctttcttac tgaggaggag gaattaaaaa attatcttgt aaaagatagt gaagaatctg
     9721 aagttataat gctagagcag aaaatgtctc atgtaaacca agcaattaat attgtttctt
     9781 cactagtgaa acaaaaaaaa tccctacttg caccaaaaag agagtttaac aaaattgata
     9841 gtgaaaaaga agggcaagtt tatgctgaag ctctggagtt aaacaatttg cacaaggaga
     9901 taggtacaat aaggtctaac ataaacttac ttaacaacaa taaaagtatg ttagaaccat
     9961 gggtgaactt tgatattcct attgaaaata tggaaactaa gtatacaaaa actatacttg
    10021 gaactgtgcc cataagcgca aacattgatg ctttaagagt aaaattagaa gatgaaatac
    10081 cagaaagtgt tattgggatt gtcaattctg acaagttaat gaactatgtt tatttaatta
    10141 ctttaaaaga aacttttgat gatgttttag aagttttaaa agaatttaat ttttcagtgg
    10201 tttcattacc aaatgaagaa ggtacaccgt tacaagctat caagaaatac aatgaaatga
    10261 taattagaca ggaaaacgtt tctaaggaca aaacagagga aattaaaaga catgcagata
    10321 gtatacacat gcttgaaaac ctatatgatt tttacactat agaaagagac caaaaaaaga
    10381 ttatagagag acttgtcaaa acaaaaacaa cattctgtct taatggttgg ttaccaagca
    10441 aaagggcaga tgaattaatt aaagaaatta cagaaaagtt tgattgttgt gttcagactg
    10501 aagaaggaag taaagaagaa ggcttcccaa ttctgcttga aaacaataaa ttagtaacac
    10561 cttttgaaag tgtaactaac atgtacagct atccaagtac aaaagatatt gacccaaata
    10621 caattttaac tttcttcttt gttatattct ttggaatgat gctaagtgac gccgcatatg
    10681 ggttaataat tgcagtagtt tgtggatttg ttgtatataa attaaagata caaaaaggtg
    10741 aaggaaattt aattaaactt attggtatct gtggagtttc aactactgta tggggtctta
    10801 tattcggggg tattttgggg gatttaattc ctataaaagc attaattaat cctttagagg
    10861 atgttatgac acttatggga atgtcgttac tgttcggtat tatccatata tatgtaggtt
    10921 tgggaataaa agcatataca ttaataagaa gtggaaaggt aatagatgca atctttgaca
    10981 taggtttttg gtatttgtgt ataacaggtg tatgtctact tataatacct tttgttgcag
    11041 gggacatagg tgtattttca gaagtaggaa aatatttagc aattataggt gctataggtc
    11101 ttgtacttac tcaaggaaga agctttaaag gtattcctgt taagcttttt aaaggatttt
    11161 caagtctcta tggtataaca agttattttg ctgatatatt atcttataca agaattatgg
    11221 cgctttgttt aacaacagga gttatagcac aagttatcaa ccttttaggg gctatagctg
    11281 gtccgatact tgcagttgta attggtgttg taggacacac aataaacctt cttataaatg
    11341 cactaggtgc atatgttcat acaagtaggt tacagtatgt agaatttttc aataagtttt
    11401 atgaaggcgg aggagttcct tttgttccgt ttaagtataa aacaaaatat acaagcatta
    11461 ataaaaagga gatgtaaata tggaattttt aaacgcgtta ggaaatggtc aatttttggc
    11521 aatatcagga gctgctatag cagcattatt tgcaggtatg ggttctgcta aaggtacttc
    11581 aatagcaggt caagccgcag caggtgttgt aacagaagac cctagtaaat tcggtcaact
    11641 tctagtttta caacttcttc ctggtacaca aggtctgtat ggatttatca tagctttcct
    11701 tattttatca aaagcaggga ttattggtgg agatgcaata ccaacatcag ctcaaggttt
    11761 acaacttctt atggcaggac ttccaattgg tttagttggt ttagtatcag gtatagcaca
    11821 aggtaaagca gcagcagcag gagttggaat agttgcaaaa agacctgaag aacttggtaa
    11881 agctataaca tttgcagcaa tagttgaaac atatgctctt ttaggactac ttgtttcttt
    11941 cttagcttac aatggaattg caattggtta attataaatt ataattcata agtaaaaaaa
    12001 atgaaaagga ggaagcactc ctatgggtaa tgaacaaaaa atgattgaca gaattatagc
    12061 tgatgccaaa caagaagcac aagaaatatt ggataaagct aaaagtgaag cagatttaaa
    12121 agtaaattca gctaatgaaa aagctgaaaa ggaaatggct tcctatacaa agcttgcaga
    12181 ggcagaagca gaaaaagcgg cttctaagga aatatcagga gcttatatgg aggctaaaaa
    12241 gcaaatatta tcaaaaaaac aagagatttt agaagaggta attttagaag ctaaaaacaa
    12301 acttttaaat cttaaagata atgaatatga agagattata ctaaacatga ttgaaaaatc
    12361 aaattgtaca gatgattcag agatagtatt atctaaaaaa gataaaaaaa cattaaaaga
    12421 tgtgctatca aaaaaaggca ttaaagtgtc tgatgaaact agagatatta ctggaggttt
    12481 catagttaaa aaaggtgaca ttgagtacaa ttattcattt gaagccataa ttgcagtaga
    12541 gcatgaatat attgaacaaa ttgcagcaga aattttgttt aattaaggag gggttaaaaa
    12601 atggcagaag aaaaaactta tccctatgcc gttgcacgaa taagagtgct tgaaaaacag
    12661 cttcttaaca gacaaatgtt tattcaaatg gcagaagcca aaagccctga agactcttta
    12721 agaattatag ctgaggcagg ttatgctgat acatcaaata ataatataca taattttgag
    12781 aatattttga ctcaagaatt atcaaagaca tatgaaattc ttaaaagtct agctcctgaa
    12841 gaaaaatttg ttgatgtatt tctttataaa aatgactatc acaatttaaa agtgctgatt
    12901 aaagaagaaa tttctggtgt agatggtgag aaatatttaa ttgatggagg tacaattcct
    12961 cttattaagc ttagagaatc tttagcaaat cgtagtttta gtgatttacc taagataatg
    13021 tcatcagcta tattagaggc atttgatgtt tataataaga cacaaaatgg ccagatggtt
    13081 gatattgttc tagataaagc aacctttacc agtatgaaag aaactgctaa agaaagccaa
    13141 aacaaatttg taatagatta tgttatgaaa gtttgtgatt taacaaatct aaagagtttt
    13201 ataagagtca aaaatatgaa gaaagatttt gatatgttta tgaatgtgtt tgtttcaggt
    13261 ggctcacttg ataaggaaaa attcttagaa gctttttcct cagatactcc agcatcatgt
    13321 tttaaatcta cttcttactc tgatgtctgt aaaaatggca tggatagtgg ttttactgtc
    13381 tttgaaaaac tttgtgatga ctatcttatg gaatatgtta gaggagcaaa atttaagcct
    13441 cttacattag aaccactaat tgcatattta tatgctaaag aatcagagat aaaaacaatt
    13501 agaattattt tgactagtaa gcttaataat atagacgcag atactataaa agaaaggcta
    13561 agggatgctt atgtataagg taggagtagt tggagataaa gatagcatca tgggattttt
    13621 agctcttgga atagatatct tcccagccta tgatagtgac gaaattaaaa aaagtataca
    13681 taagttggtt gaagatgaat atgcgataat ttatattaca gaacaggcat cattgcttgc
    13741 aaaagaatca atagcaaaat acaaagatta ccaacttcct gccattatag ttattccagg
    13801 tattggagga agtatgggat taggtatgaa tgaagtaaga gaatctagta aacgtgctat
    13861 aggtgcagat atattattta aagaatagat gaaagttgaa taaaagacaa tctcaaattt
    13921 tattggtgct aaatatatgt gctaataaaa tataggaggg aatatttaaa ttttgataaa
    13981 gtatatgatt gcaggtgaga gaatatgaaa acaggcacaa ttgtaaaggt gtcaggaccg
    14041 cttgttgtag cggagggcat gagagatgcg aatatgtttg acgtcgtaag agtttcagat
    14101 aaacatctta taggcgagat tatagaaatg catggagata aagcttctat acaggtttat
    14161 gaggaaactt ccggtctagg accaggggaa gaagtagttt ctcttggaat gcctatgagt
    14221 gttgaacttg gaccaggtct tatttcaact atttatgatg gtattcaacg tccacttgaa
    14281 aaaatgtatg atatttcagg tactaatata actaaaggtg ttgaagtatc ttcacttgat
    14341 agaacaacta agtgggaatt taaacctaaa aaatctgttg gtgataaggt tgtagcagga
    14401 gatataattg gtggcgttca agaaacagca gtagtagaat gtaaaattat ggttccttat
    14461 ggagttaagg gtactataaa agaaatatat tctggtgaat ttactgttga agatacagtt
    14521 tgtgttatta cagatgaaaa aggtaatgat atacctgtaa ctatgatgca aaaatggcca
    14581 gttagaaaag aaagaccata tagagaaaag aaaacaccag attcacttct tgttacaggt
    14641 caaagagtta tagatacatt tttcccaatc acaaaaggtg gggtagcagc tataccggga
    14701 ccttttggaa gtggaaaaac tgttacacag catcagcttg ctaaatgggc agatgcagat
    14761 atagttgtat atataggctg tggcgagcgt ggaaatgaaa tgacagatgt tcttcttgaa
    14821 tttcctgaat taaaagaccc aagaacaggc gagtcactta tgcaaagaac tgtgcttata
    14881 gcaaacacat cagatatgcc ggttgctgca cgtgaagctt ctatatacac tggtattaca
    14941 atagctgaat attttagaga tatgggatat agtgttgcac ttatggcaga ctctacatca
    15001 agatgggctg aggctcttag agagatgagt ggtcgtttag aggagatgcc tggtgaagaa
    15061 ggttatcctg catacttagg ttcacgtctt gctcaattct atgagagagc aggaaaggta
    15121 aattgtctag gtatggatga aagagaagga acacttacag caattggtgc agtttctcct
    15181 cctggtggtg atacatcaga acctgtcagc caagcaacgc ttcgtatagt aaaagtattc
    15241 tggggtcttg atgcatcttt agcatataaa cgtcatttcc cagcaattaa ctggttgact
    15301 agttattcac tctatcagga aaaagttgat gtatgggcag ataaaaatgt aaatgataat
    15361 ttctcagctc aaagagctca agctatgaaa cttttacaag ttgaatctga acttcaagaa
    15421 atagttcaat tggttggggt tgattcactt tcagatggag atagattgat actagaggtt
    15481 actcgttcta taagagaaga cttccttcat caaaactctt tccatgaagt tgatacttat
    15541 acatcacttc ataaacaata tagaatgatg ggacttatat taaaattcta taagtcagca
    15601 caagatgcta tcaagcaaaa tgttactata aacgatatta tcaagctttc agttcttgaa
    15661 aagattggtc gtgctaagta tgtagaagaa ggcgatatag atgcagctta cgattcaatt
    15721 gaagatgaaa tagacaacga gcttgcagac cttattaaaa agaggggggc tgaagaacta
    15781 tgataaagga atataagtca atacaagagg tagccggtcc tcttatgtta ataaacggcg
    15841 tagaaggtgt aaaatttgat gaacttggag aaattgaact ttcaaatgga gaaattcgtc
    15901 gttgcaaagt tctagaggta aatggagata ctgcacttgt tcagcttttc gaaagctcaa
    15961 caggtataaa ccttgctgaa agtaaagttc gttttttagg aaagagtctt gactttggag
    16021 tttcaccaga tatattaggt cgtgttttta gtggaatggg tagacctatt gatggaggtc
    16081 cagaaattat accagataaa agacttgata taaatggagc tccaataaat ccagcagcac
    16141 gtgattatcc ggccgagttt atacaaactg gagtctctgc tatagatgga cttaatacat
    16201 tggttagagg gcaaaaactt cctatattct cagggtctgg tttgccacat gccaatcttg
    16261 cagttcagat tgcaagacag gcaaaagtac gtggaactga ttctaagttc gccgttgtat
    16321 ttgctgcagt tggtataact tttgaagatg ctgaattttt tataagcgat tttaaagcaa
    16381 ctggtgcaat cgaccgttct gtagtgtttg taaaccttgc aaatgaccca gctgtagagc
    16441 gtgtatctac acctagaatg gcacttacag cagcagaata ccttgctttc gagcaagata
    16501 tgcatgtact tgttataata acggatatta caaactatgc agaggcattg cgtgaagttt
    16561 cagcagctaa aaaagaagtt ccaggacgtc gtggatatcc aggatatctt tatactgacc
    16621 ttgctactat gtatgaaaga gcaggaaaaa tgaaagggca tgaagggtct ataactatga
    16681 ttccaatact tacaatgcct gaggatgata agacacatcc aattcctgac cttacaggat
    16741 acattacaga agggcaaatt atacttagcc gtgaacttta taaaaaagat atacagcctc
    16801 ctatagatgt tttaccatca ctttctcgtc taaaagataa aggtattggt aaaggtaaga
    16861 ctcgtgaaga ccatgcagat acaatgaacc agctttttgc agcttattca agaggtaagg
    16921 atgcaaaaga acttatggct atacttggtg aatctgcact ttctgagatt gatttaatgt
    16981 atgctaagtt tgcagatgaa tttgagaaag aatatgtttc acaaggattt agaactgata
    17041 gaactattga gcagacatta gaaatcggat ggaagcttct tagtatgtta ccaaaaagtg
    17101 aacttaaacg tatccgtgat gaatattttg aaaaatatat gcctaaggag tgatatctgt
    17161 ggctagatta aatataaatc caacacgtat ggaaatgact agacttaaga aactccttaa
    17221 aactgctaca agaggtcata agcttcttaa agataaactt gatgaactta tgaaacaatt
    17281 tcttgagatt gtaagagaaa ataagcgatt gcgtgaagaa gcagaaaatg ctcttgatac
    17341 tgcttataaa aactttataa tcgcaagagc agttatgagt caggagtatc tgggttcagc
    17401 acttatgatg ccaaagcaat cagtttcagt agatgtttct acgagaaata taatgagtgt
    17461 tgatgttcct gtgtttgact ttaaaactga aaacaatcaa agtgatattt atccttatgg
    17521 tcttgctttt acatcaggtg aattagattc tgctatggaa gctttctcag atgctatgca
    17581 accactttta agacttgcag aaagtgaaaa aagtgcacag cttcttgcac aagagataga
    17641 aaagacacgt agacgtgtta atgctcttga aaatgtaatg ataccaaatt acattgagac
    17701 tattaagtat atagctatga agcttgaaga aaatgagaga gcaagtacta ctagacttat
    17761 gaaggttaag gatatggtgc ttaaaaaagc acttgaagaa aagaaaaaaa atgatttggt
    17821 tgtataatta aatacttata aaaataagtc taacattcta ctttatagag gttagactta
    17881 ttttttatgt ttaaattaaa atgtagatac tataaaaatt aatatattgt ttaaaaacag
    17941 actgtattta actaaaaata atatatttaa caaaaatttc taaaaattaa cgaactgtta
    18001 atttacactt aactttatat taacaaatta ggtgtattat ataaacataa gcaaaaacaa
    18061 taaaaaacaa ataaaaaaag gaaaaaacac aaagggggaa gatatgaaag aatttatatt
    18121 tacttgtctg tgcattgtag tgattacatt tatgacaagt tgcatatcaa caacaccaca
    18181 aactactcaa ggaaaaggaa ataataaact tacaatatat gcagcactag aggaagagca
    18241 gatagcttat tatatggaag gttttagaga agagtatccc aatatagatg tagagatagt
    18301 tatggattct catggtgtaa tagcttcaaa actattagca gaaaaagata atccacaagc
    18361 agatattata tggggattat cagcaatgaa catgatagag ctaaaaaaag atggtgcact
    18421 tgaagcatat aagcctaaaa attatgataa agttgataaa aaatttaaag atactgaaga
    18481 tgatgtatct tgggtaggaa tgagtgtccc agagacagca atagtagtta attataagga
    18541 acttaagaaa ctaggtatag atattccaaa aagttatgaa gatttaataa aaccagaata
    18601 taaaggactt ataacaatgc caaatccagc atcatctgga acggggtatc ttacagtatc
    18661 agggcttatt caaatgatgg gtgaaaaaga tgcttacaat tacatggata aattacataa
    18721 aaatatagcc acatatacac actcgggttc aaaacctgcg aagttagctg gctctggaga
    18781 gtatccaata ggtattacac ttggatatag agctacacaa caattatcta gtggagaacc
    18841 tatagaggtt gtatttccaa aggaaggttc aggttgggac ttagaagcaa atgccttagt
    18901 taaaaaagat aatataaaaa aagaagcaaa gctattttta gattgggcaa taagtgattc
    18961 agctatggat agatatgcac atgaagtagc agttacttcc ataaagacag ataatccagt
    19021 tccaaaaggt tattctaaac aaccatttga acagcttata aaagaagttg atttaaactc
    19081 tgctgccaaa aacagaagta cagtacttaa aacttgggaa tcaaaatacg gttcaaaatc
    19141 tgaaagtaag taaagtttaa attaataatt tagatgaaag aattttagaa gaaaaagtag
    19201 gatataaaat ttaaaataaa aaaataacta tataaggaga gataagatat gagttactta
    19261 aaaataaata atgtgtttaa aagttatgac caaaaaaagg ttttaaataa tattagtttg
    19321 gatattgaag aaggggaatt tctatgttta ctcggaccta gtggatgtgg taaaactaca
    19381 ttacttagaa taatagcagg tcttgaagat gtaaatagtg gaactataat tctccaggat
    19441 aaagatatta caaatttaga gccatcaaag agaggttttg gtatagtatt tcaatcatat
    19501 gcattatttc cgaatatgac tgcttataac aatatagctt ttccactaaa agagagaaaa
    19561 gtttcaaaag aaaaaataga taataaagtt aaggaagtac ttgaaacagt tggattgact
    19621 aatgaagctc ataaataccc taaagcatta tcaggtggac aacaacagag gattgcaata
    19681 gcaagagcat tagctcttga accaaagttt ttacttttag atgaaccaat gtctgcatta
    19741 gatgcaaagg ttagacacaa gcttagaatg gacattaaaa gattacaaaa agaacttaat
    19801 ataacgacaa taatggtaac acatgaccaa gaagaagcta taactatggc agataaaata
    19861 gctattctaa atggaggaga tataatgcaa atagggactc cagaagaaat ataccaaaat
    19921 cctcaaaacc tatttacagc tcaatttata ggagatacaa actgttttga taatggagat
    19981 tctatattaa ctgtaagacc agaatatgtt caaatagaga aatcgacaaa agaaaactac
    20041 caagggataa tatcaaatat agagtttaga gggaatttat tgagagttga aataaaagat
    20101 aaattaaatg aaaatttcat aataagtgat gtttctataa aagagtgggt taatttaaat
    20161 ttagtagaag gtgaccttgt aaaaataagt atagacgaaa aatactattt aaagtatcca
    20221 aaagttaaag gagcataagt gtatgaataa taatgctata agttctaaaa gtataagtct
    20281 taaatcaaaa atgaatttag atataaaaaa atgtatgctt acagtattag ttatgtcttt
    20341 agtaatattt ttattagcac ctataatata tctatttgta caggcttttt tagataaaga
    20401 tggagtcttt gtaggattac aaaactttca agaatacttg gcttctgaat ctctattaaa
    20461 ttctctaaaa aatacagtat ttgtatcagt tatatcaact gtaatatcac taacacttgc
    20521 attagtatat gcatatgcat taactagaac aaagattaaa tttaaaggtt tttttaaatc
    20581 attagctatg tttcctatgt ttgctccaac aatgatgcat gcaataggtc tagtatattt
    20641 atttggaaat caaggtttgg taactaattt acttggagtg catgttccaa tatatggagc
    20701 agtgggaata atattggcac aaattatata tgtatttcct caatcatttc aaatacttta
    20761 tatatctcta agttcaaccg attatagact atatgaagct agtaatacta tggggataag
    20821 caagataaga gaatttataa gcataacaat cccaagtata aaatactctt taataagttc
    20881 tgcattcgta tcgtttacat tatgttttac agattttgga gctccaaagg tgataggagg
    20941 agagtttaat gtattatcaa tagatgtata taagcaaatt atagggcaac agaatatgcc
    21001 aatgggagca actgtatcaa tattactttt aatacctgca ataatatcgt ttatagtaac
    21061 taaaaaaatt gaaaaaaatc aaaattcata tataacttca aagtcaattc catataaggt
    21121 taaaactaat aagttaagag atagtatttt aggaggggtt gtaggaatta ttgcatttgg
    21181 tataatagct gtaatgttaa ctgtaatctt atcttcatta atatcagttt ggccatatga
    21241 tttaagactg acactggaac atttttctat gaaaaacagt attgatggga ttaaaccatt
    21301 tataaattca ataaaaatgt cactatttac agctattcta gggacgagct ttgttttctt
    21361 atttgcatat ttgaatgaaa aaacagaaaa agctccatat ttaaaatcat ttgggtattt
    21421 tttaagtaca ttgcctatgg cattgccagg attagtttta ggtatagctt atgtattatt
    21481 ttttaataaa ttagagttta attttatgga tacaatatac attaagaatt tgtttaatgg
    21541 attatatgga acattactta taatggttat atgtaatata gttcatttct tttcagtagc
    21601 atttataaca gctactactg ctattaagaa agtagataaa gaattagata tggtagctaa
    21661 atcaatggga ataaacagcg catcaattct taagaacgta actataccac tttgtttgcc
    21721 agcagtttta gagaacttta tgtacttttt cctaaactcc atggtgacaa tatcagcatt
    21781 agtttttata tatactgcaa gttcaaaagt agctgcaata tcaattgtac aactagatga
    21841 taaggggagt actgcacagg cagcagcact agctgtgtta atattagtca caaatatatt
    21901 agtgaaagta atatatgaat ttataaagaa tcgtttagaa aaaagaacaa actttaatta
    21961 aataatttat cttataaaaa cacaaattta aaaaagtcta ttcttgtgat ttattattta
    22021 aagaatagac tttttaaatt tattattgat attgtttatt aattttcctt ttgttatcat
    22081 acatttgaga atctgcacga cgatatgtat caaataaaga aacatctact ttttcatcaa
    22141 aaatagcata tccaatagac attgataatt ttaattcatt agttgagttt tcttcaacta
    22201 tttttaaatt aatattattt ataatattat ttatttcttt gtgagataaa ttttttagaa
    22261 taattatgta ttcatcacct ccaatacgat aaactatata ttttttattt attacatatt
    22321 gtataatttt acttgcttgc ttaatatata agtctcctgt ctgatggcca aatttatcat
    22381 taatcttttt taaaccgtct aaatctattg atatgataga tattagattc tttagatttg
    22441 aattgtttaa gttattcata tctatttcaa aagcatttct attttttagg cctgttaaat
    22501 aatctgtatt agcaaaatca gtatatgtag gattagatat tcttttaaat agaatcactg
    22561 caatcaatgc tgatattaga caagttaata atgctattat tggtgtaact atacttataa
    22621 atttaaatgt attgtattga tgttttgctt caaattcaat tcctattact ccaacaacct
    22681 taccaacatc attgtgaata ggaaaatacg atataaatat gtatccccaa gatgttgatt
    22741 taatcttttt aggtaacaat atatgattat ctaatgcttt gttaaggtct ccccaaatct
    22801 ctttttctat caaatcacca gcatttctaa aatcactcct agatgaattt aaaccatcaa
    22861 caacatatac tagtgatcca tcttttgttt ttttagcagt atatagatac atgactccag
    22921 tagtattttt tacagattct aaaaggattt tagaactttt ataagacttt tttgattggt
    22981 cttctttaga attaatttca gtaaaggtat ttttatcaat atttctttct acatattcat
    23041 agatatgttt tgacctctca cttaaagagt atatcatgct cttataagtt agtgtataat
    23101 taaaaaaata tacacatgag gaagatatta ttacaataat tgcagtaagt attgaaacct
    23161 gcatatcaac tctattgaat tttttattta ttttcatagc ttaaatgtct tgtgaaaaga
    23221 acctcccaca atctccccat aattaatata tatctataaa tttcaccata atatattcat
    23281 atattatcaa atttgtgtgg aaattacaat tagtaaacat gcttaaagca ttcaaatata
    23341 gtttttttat tattatagta tactatttta tgtataaata aaattatata taaatcattg
    23401 atattggttg tttattaatg gaagataccg tataaaatat tctaattggt tacgatatgt
    23461 atacttaatt gaagttaagt taagggttag aatatgtatt gatgaaatgg ctagatttat
    23521 attcataagt attaatttta tcatagatag gtaaaatact gtatcttaaa cataagtatg
    23581 attgagatgc aatcctgaga tatgataata taaattgaag gatagtgaac tcaatcaaat
    23641 aaaatgatta atctagctat ataagcaaat aaatttaata taaaagaggt ggaaaatgaa
    23701 agacagactt aatttaacag aaggaagaat tacagaaaaa ttacttaagc tatcacttcc
    23761 aataatgggg acttcattta tacagatggg gtataacatg atagatatga tatgggttgg
    23821 taaagccgga agtaaagcag tagctgcagt tggaacagct ggtttttttc catggcttgc
    23881 aatggcattt attatgattt caaaagtagg tggagagata aaagtagcac aaagtattgg
    23941 tgcaaataat ataagcacta ctaaatcata tatgaagtca gcaatagaaa taaatattat
    24001 actagcaata atatatacaa tttctttaat agtacttaat aaacaattga taggtttttt
    24061 tagattagga gacttagaag ttataaccat gtctagacag tatttgataa tagtagctct
    24121 aggtatggta ttttatttta ttaatccagt atttactgca attttcaatg gtcttggaaa
    24181 tagtaaaact ccttttcgta ttaatacagt aggattaata actaatatta tacttgaccc
    24241 tatattaatt tttggatggg gatttgctcc aaaacttggt gttgcaggag ctgctattgc
    24301 aactgtattt gctcagatag tagttactac atgttttata tatataatag ttaaaagtaa
    24361 agaagaatat tttaaattaa gactatttaa agaaatagag actaaatatt ataaagttct
    24421 gtataaattg ggattaccta tagcaataca aagtggtatg tttacagtat tctcaatgct
    24481 attaggagta atagtagcat catgggggcc tgtggctgtt gcagtacaaa aagtaggctc
    24541 acaaatagaa gcaatttcct ggatgacggc tgaagggcta tcagttgcat taggcagttt
    24601 tgttggacaa aattatggtg ccaagaagta ttctagaata aataaaggtt gcaaaatagc
    24661 tataactgta tcttctgtac ttggtataat aactacttta gtattagtgt ttgcaggaga
    24721 gagtatattt tctattttta tagatgaaag tgaggcaata gaaaaaggag cagtttatct
    24781 taaaatatta ggctattctc aattttttat gtgtttagaa ataataacaa caggagcttt
    24841 caaaggatta gggagaacct atataccttc tattataatt actatactga ctggtgcaag
    24901 agtaccattg gcttacttta tatctagacc agaaatgttg ggtctaaatg gtgtatggtg
    24961 gagtataacc ttatcaagta tattaaaagg tatattaatg ataagtctat ttatatcttt
    25021 attaaaactc ggaaagttgt acaagatttc tgaataaaat ttaaattatc ttaaatgtat
    25081 agacattttc tttgtttgta tataaaatta tcttattata taaaagattt aataaggagt
    25141 gaattaaatg aaagagccaa tttataaagt tatagaaaat catgttagag agttaataaa
    25201 ttcagacagt ttgaaagaag gggatttaat cccttctgaa aaacagctga gtgaagaatt
    25261 taatgtaact agaatgactg taaggtctgc acttaataat ctagttaaag aaggctatat
    25321 aactagacaa agaggtgtag gtagtatagt tattgcaaat aatatatatg ataatatatc
    25381 gtctgtaagt ggatttacta aagagatgga aagtaaaggc tataaagtat ctaatatatt
    25441 ggtatctctt gaaatagttc aggcagatga aaatttatca agtaagttga atataagttt
    25501 agaagaaaat gtttgggaaa taaaaagagt aagattagcc aatgatgcaa gagtttcata
    25561 tatgattact tatatgccag ttaagttatt tccaaattta aataagactc attgtgaaaa
    25621 ttctctttat aattttgttg aagaagtgtg tgaatacaag atagccatgt cagagagaga
    25681 agtacaagct gtaatatcga atgaagagtg tatggataat ctaaaattag aagaaccaga
    25741 gccactttta tatataagcc aaatttgtaa gttacaaaat agtgagattt ttgagtactc
    25801 acacacatat cactatggat atacattaac tttgaatgct gttgtcgaat aaaatttaaa
    25861 taaaatgaaa aagttttctt gaaatgtata tacatttggt atataataat atcaagaatt
    25921 aaatgtatat acatttaaaa ataagatata tacattaaga aaaaattaat agaaaaacat
    25981 attttaaatg tatagtttaa aaaacttatg acttaaaaaa tatttaatga atctaatttg
    26041 gaggggaaaa aatgataaaa ataatgttag cttgttcagc aggaatgtca actagtttat
    26101 tagttacaaa aatggaggat gcagcaaagg aaaacggtat agaagcaaaa atatgggcta
    26161 tatcagaagt gaacttaaaa aatgaaatag aaaattgtga tgtcttactt ttagggcctc
    26221 aagttagata tgtattagga aaagcaactg aaatggcaaa accatataat attccagtag
    26281 aagttataaa tatgatggat tatggaagat gtaatggaaa agctgtgtta gatagagctg
    26341 tagagttaaa tagttcaaaa taaagttgta ctggaggatg taaaatggaa aaattcatgt
    26401 catttatgga taaatatata gtgcctgtag ctgctaaaat aggagctcaa aggcacttag
    26461 tagcagtaag agatgcattt atagtaatga tacctataac tatggtaggt gcattgggaa
    26521 cattgataaa taacttacca ttggaagcat acaaaaattt gatggcaagt atatttggag
    26581 aaaactggac cacatttgga ggcgaccttt ggtggggagc aataggtaca atggcagtat
    26641 tcttagtaat aggtgttgct tattttctag caaaatctta tgagagtgat gggttacaat
    26701 ctgggcttat agctttatct atctttttta taatggctcc acaaattggt aaaatagttc
    26761 ctgagggagg aactacagta gttgaaggat ggggaatgat acaacaaacc tacttaggta
    26821 cagcagcttt attctcttct atattaatag gattattatc aactgagata tttgtaagat
    26881 tatctaaggt aaagaaatta actataaaaa tgccagatgg agttccacca gcagtttcaa
    26941 gatcatttgc aaagttaata ccaggaatgt taactataat gatatttact gtaataggaa
    27001 tatttataaa aatgctttct aatggaagtt tcttaacaga tattttaaat acttatttag
    27061 gagcaccact atcaaatgta gctgatagtc taggttctac aatgcttatt gcatttataa
    27121 ttcatatact ttggactgtt ggacttcatg gtgcaaatat agcacttcct tttacagaaa
    27181 ctatacttat gaaattaggt ggagaaaatg ctgccttggc tcaagcagga gcaacggaag
    27241 gataccatgt acttgcaggt gcattctttg atgcatttgt atatttaggt ggttctggaa
    27301 tggtattggg attaatagta gctttattaa tagctggaag aagacgtaaa gagatgatag
    27361 tattaggtgg tccacctgca atatttaaca taggagaacc attgatattt ggacttccaa
    27421 tagttttaaa tcctatattt atgattccat ttgtacttgc accagtaata tgtagtgctg
    27481 tatcatactt agcaatagat tttggattag tagcaccagt aattttacct aaaatacctt
    27541 gggtaacacc tcctatatta ggtggagcaa tggctacagg tgactggact ggcggagctt
    27601 tagcactatt taatttaata ttatcaatat taatatatat tccatttgtc atagcgtctg
    27661 aaaaaatgga agctaataaa ttgaaaatta acaactaggt agttttattt cggtaaataa
    27721 atgtatagag ttttaaataa atgtatgggg ttttgtagag tatattaaat tataggtaag
    27781 gatggtataa tgagatgaaa aagggactaa aaatagttac aattggagga ggttcaagtt
    27841 atactcctga gcttgtagag ggttttataa atagatatga agagttacct gtaaaggaat
    27901 tatggcttgt agatatagaa gctggaaaag aaaaattaga gatagttgga aatctagcta
    27961 agaggatggt aaaaaaagct ggagtagata tgaaaataaa tcttacttta gatagaagag
    28021 aagctctaag agatgcagac tttgtgacaa cacaacttag agtaggtctt ttagatgcga
    28081 gaataaaaga tgaaactatt cctttatctc atggagttat ggggcaggaa actaatggtg
    28141 ctggaggttt atttaaagcc cttcgcacaa taccagttat atttgatata ataaaagatg
    28201 tggaagaatt atgtccaaat gcatggatgg tgaattttac aaatccaaca ggaataataa
    28261 cagaggctgt attcaaatat actaatttta gaagatatat aggtctatgc aacgtgccaa
    28321 ttcatttaaa aaatgatgtt gccaaactat ttaatgtaga aagtgacaga ataagtatgg
    28381 attttgcagg tcttaatcat atggtttatg gtctaaatgt atctttagat ggagaagatg
    28441 ttacaaaaga agcaattgat aaatttgtca aagcagatat aagtatgcaa aatataaagg
    28501 caattgattt taatgctgaa tttgtaaaat ctttgggtgc aataccttgt ccataccata
    28561 gatactacta taaaactaaa gaaatgcttg aggatgagtt gagagagttt aaagagggaa
    28621 aagctagagg tcaagtagtt aaagaattgg aagaacaatt atttgaatta tataaggatg
    28681 aaaaattaga tgtaaaacca cctcaacttg aaaaaagagg aggggcttac tatagtgatg
    28741 ctgcttgtaa tttaataagt tctatataca atgacaaaaa agatatccaa gtagttaata
    28801 cattaaataa gggttctata agagatttta aagatgaaca agcagtagaa gtaagtagtg
    28861 taataacaaa aaatggtcca aaaccaataa gtataggata tttaccagat tctgtgcatg
    28921 gattagtaag tcaaatcaaa tcatttgaag tattggcagc taaagcagct gtatatggcg
    28981 attatgaatc tgctcttttg gcactttgta taaacccatt gattccatct gatgacttag
    29041 caaaaactat attagacgaa atgttggaag ctcataaaga ttatcttcct agatttaata
    29101 gatagttgtc tatagaaagt aggttatggt atgactaaaa ttataataaa tgcagatgat
    29161 tttggatatt gtgaagctgt gaactatgga ataatttcag ctcataataa tggtatagtt
    29221 aggtctactt ctatgatggc aaatatgcct ggggtagaac atggagtagg cttacttaaa
    29281 gaaaataaaa ctttaaattg tggagttcat atgactttaa gttgtggtag accattatta
    29341 tctaacttaa aaactattgt tgataaagac ggttttttta ttaggaggat tacagacgaa
    29401 attattgaaa aaatggattg tgatgagatt tatagagaac tttgtgctca aatagatagg
    29461 gtaaaagggc ttggaataga tatatctcat ttagatagtc accatcatat ccatacttta
    29521 gtaagtttaa agccagtaat agagaagatt gtaaccaagt ataatcttcc aataagaggt
    29581 ggatttgaat ataatttaga gtattctaaa gtagttcctt taatagatag tttttataag
    29641 gaaaatgtaa gtgaagaata ttttataaaa aatatagacg aaataatgaa gtatgatgta
    29701 gtggatatta tgtctcaccc agctttttta gatgattata ttttaaattc tacatcttat
    29761 gctattgata gaacgaaaga gcacaagata cttacatcta aaaaagtcaa agaattttta
    29821 gaaaagaatg gattagtcat atcaagctat agagatattt aggaggtcga ataaatggat
    29881 gagaagatga tagagatatc ttttggaata attggatttg caggtgatgc gaaagggcta
    29941 gcatttgaag caataaaaga agcaaagagc gggaatatag ataaagctag agaatgtatt
    30001 gaaaagtcga aagaatcaat tcataaagct cataaattcc aaacagaatt gatacaaaat
    30061 gaagctaatg gtaataaaac tgaaataagt gttatactta ttcatgcaca agaccattta
    30121 atgacagcta tgaattttca acaattagca gaagaattta tagatgtata tgaaagatta
    30181 gaaagtaagt aatttaaaat tattattaaa aaagagtgta taaaaataat ttttataatt
    30241 attaaatgca ctcttttttt atttaagtag agtttagcaa tatagtatta tgttattgat
    30301 actttagaat ttagacttct cataattgta aggtatacta gtaccaacaa ctacatcttc
    30361 aattttttca acaataagcc aatcatccat atttccttga tggtcaaaat caagaggtgt
    30421 tatttcttca acattttcaa attcaactaa gcataaacat tttttatgcc aacgaacttt
    30481 ttgcttttca gataaattta attttggttg attttcattt aaaattttag aaatttcatc
    30541 ttctgttaat ttaacatagt tttctacctt tttaacagtg gcttttgcag atatttttgc
    30601 agttcctttt tccataaaat aaagtaactc atcttcaaat actctactat gtggtatttt
    30661 tctaccagca gcacctctaa taaccattgt ttttgttcca tccaagattt tatctaagac
    30721 cttttctcct ttttttcctg cattatcaca atatactaaa tgtaccatgt tttgaatcct
    30781 ccctactaaa ttccttatct ataaattgca ttttatcatt gtttaactga aaagtcattg
    30841 tatttgtgtc caattcttaa aaaaaatact gtttaatata agaaaacctt atctaagcta
    30901 tatataatta agattaatta ggaattttta tccttttaca aaataatatt gactaaaaat
    30961 agaaaaatgc tataataaat atgtgcttat gataatcaat atcatgtaag tataataaac
    31021 aagtaggaga agtaatcatg aaaaaaataa aatcacttgc aatatttata tctattataa
    31081 ctacgttagt acttgttaca gcatgttcag ataagaatac agaggataaa gataaatcag
    31141 agacaagagt tgtacaatct gttaaaggag aggttaagat accatcaaat cctaaaaaaa
    31201 tagttgatat atcaggaagt agtgaagaac tattattagc aggttataag cctgttgcaa
    31261 cagcaaatgt agactcatat gaaactgata aattaccaag ttacataaga gaagagctta
    31321 aaggtgtaaa gatagttggg cactcaatga tggatactat ggatatggaa gctatattag
    31381 aagtaaatcc tgatttaata ataatgagtc aaagacaaga aaaaatatat gaccaattaa
    31441 aagaaatagc tcctgtagtt atgatgaaag attatgcaaa tgactggaga agcaagttaa
    31501 ctgatgtttc aaagttattt gacaaagaag aagaagataa aagttggcta cagaagtatg
    31561 atgaaaaagc tacaaagtta ggtaaggaag ttatagaaaa gaatggagaa aaaacttatt
    31621 taccagtgtt ggcaagttca ggtcaattta tggtatttag tgatggtgga ataggtactc
    31681 taatcaatga tgatatgaaa ttagctagac ctaagaatat gccaaaacag gatggaataa
    31741 cactaccaat ggtaagtatg gaaggtttaa cagatataga tgcagaccat atagttgtaa
    31801 ttgctacaga agcagataaa aaagatttag aaaatagtgc tatctgggct caaataagag
    31861 cagtaaaaga tggtaatgta acaatacttg atgctgctcc atttttcagt caatcataca
    31921 atccaattgg aaaagagtta ttattagaat cagttaaaaa tgaattaaca aagtaattct
    31981 taacttagta ggtgtgagat aatgatattc atttttcaca cctattttta ataaatctta
    32041 aaattaaaat acttaataga tgatattata ctgacgatta aaagggaaaa ggaggtagga
    32101 taattgacta agctgagtaa aaaaaatata acttatttgt tgatattagt aagtatagtt
    32161 gtacttgtat ttggaattgt attatccata actattgggg caaaagatat gaatctatca
    32221 actgttatag atagtttgat aaaaatggaa gatggaataa atatgagaat agtaaaggat
    32281 gttagacttc caagggcaat agcagctgca cttgttggag ggtttttagc agtttctggg
    32341 gcaataatgc aaggaataac gagaaatcct atagctgaac catctgttat aggaattaca
    32401 caaggagcta cattcgcaat ttcgatatca ctggtacttc aaaaaaaact tcctcaactt
    32461 atacatggaa gttttagtgt aatgatgttt gcatttattg gagcaagtat aagtggatta
    32521 tttatatatt ttataagttc taaatcaaga ggaagagtta ataatgtaaa attagctctt
    32581 gcaggagtcg ctcttggtac attgctaatt tctttggcat cagcaatatc tatgtatttt
    32641 aacctatctc aacaattaag tttctggata tcaggagggc ttgtaggagt gaagtgggaa
    32701 ggtataaaat tgctatttgt agctggtggt attggattta ttttagctat tattatggct
    32761 ccaagaataa ctatattaag tcttggagaa gaagtggcaa taggattagg acaaaaaact
    32821 aagtttgtta gatttatatg tatagtactt gtaatattaa tgactggagc atctgtgtca
    32881 gtgtctggta atattatttt tataggtctt atagttcctc aaatagctaa aggaatagta
    32941 ggttcagatt ataagtatat aataccgagc tctttagtat taggagctgt attgcttgta
    33001 tatacagata tattaagtag gatgataaat cctccatatg agacaccagt aggttctata
    33061 acagcactta taggagtgcc aatatttata taccttgtta gaaaggggga gaaataggta
    33121 ctatgaaaaa tattataaaa ataaattcta aaacattact tgttatatca attttaatgg
    33181 tgcttatttt tatcactttt ttattgagtt taaatatggg ctcattttct atagaaccaa
    33241 tggatgttat aaagactttt ttagggcagg gtcagcgtaa tcatgaaatt gcaatattta
    33301 aattaagatt accaagaata gtaatagcac ttttggttgg ttctgcatta tcaacagcag
    33361 gtgtaatact tcaaggagtt acaaagaatg atttagctga ttctggaatt ttgggaataa
    33421 attcaggtgc tgcattgttt gtagtagttt atatatacct tatgaatggt aatgtatatg
    33481 aaggtatgag taacttgact gtatttacaa tgcctattgt tgcacttata ggagctttat
    33541 ttggagcatt tcttatatat tctcttgcat ggaaaggtgg tataaattcg tcaagattac
    33601 tacttattgg tataggtgta aacatagctt ttacttcaat tttgacgata ttccaattga
    33661 aatttacaac acaagaattt aatagggtta tggcatggac atcaggaagc atttggggaa
    33721 caagttggaa atatgtaata gctgtgcttc catttatagt gatttttatg ggtataacta
    33781 tttataaatc taaatatata gatgttttaa atttgggtga tgaagtatct ataagtcttg
    33841 gtgtagatgt agaaaaacaa agaagaagac ttataatata tgcagtaatt ttatctggtg
    33901 tatcgacagc agtagcaggt agtatttcat ttttaggttt aatagctcca catataggta
    33961 gaaaaataat aggaccaaag cataaaagat taataccagt atcagcattg ataggaacat
    34021 tattactttt aatagcagat actatatcaa gaaatcttct agcacctata gaaataccag
    34081 taggtatagt agtttctata ataggagtgc cgtactttat ttatttaatg ttggtaaatg
    34141 attaggaaag ggtgttgtta tgaactgtat aaatactaag aatctaaatg tatcatatgg
    34201 aaacacagat attataaaaa atttaaattt aaatatacca aaaggaaaaa taactaccat
    34261 cataggggct aatggttgtg gaaaatcgac aatacttaaa actataggta gaattattag
    34321 ccctaatagt gggaaaatat atataaatgg agaggacatc tacaaaaaga agtctaaaga
    34381 aatagcaaaa gatatggctg tacttccaca aagccctcaa gctcctagtg gtcttaccgt
    34441 ttcagaatta atttcttatg gaagatttcc tcataaaagt ggatttggta attctagtaa
    34501 agaagacaga gagattgtaa attggagttt agaagttact ggaattgcag aatttaagga
    34561 tagaaatatg gaagatttat caggaggaca aagacaaagg gcatggatag ctatggcttt
    34621 ggcacaagaa actgatatat tattactgga tgaacctaca acatatttag atttggcaca
    34681 tcaattggag atactaaaat tattagatga actaaataaa aaacaaggaa gaactattgt
    34741 catggtaata catgaactta ataatgcagc aagatttgct gaccacatga taggtattaa
    34801 gaaaggtaaa atagtttgtg aaggtgatgc atatgatgtt atgacgaagg ataatctaaa
    34861 agaattattt aatattgatg cagaaatagc aacagaccca agaacaaata aaccaatttg
    34921 tataacttat gacatggtgt aaatggtgac aacatggaga atcaagaagc attaagacat
    34981 gaaaaaatat ggattttatt atttaggtat tcgatacctg caataatagc aatgatggta
    35041 acttcacttt ataatgtagt agatagagct tttattggtt ctatggaagg tattggctct
    35101 atagctattg caggtcttgg tgtaactatg ccagtattta ctctaataat agcttttgga
    35161 atgttggtat cagtaggtgc tagcacaaga ttgtctataa agttagggga aagaaataga
    35221 gaagaagcag agaagatatt aggtaatgct ttgacattat ctataattat ctctttaatt
    35281 ataactatat taggattagt tttcttagaa gagatacttt ttattttggg tgcaagtaaa
    35341 gattcaatat tttatgcaaa agactatatg agtgtcatat tggttggaag tatatttaat
    35401 ttagttgcat tttctcttaa taatgcaatt agggcagaag gtaatccaaa attagcagca
    35461 aggacaatga ttgtaggatg tgtattaaac ctgatattgg accctatatt tatatttgta
    35521 tttaatttag gtataaaagg agcagctata gcaacagtac tctgtcaaat agtagtattt
    35581 ttttgggtaa tacattattt tataagaggg aagtccaatt taaaactaaa aaaatgtaac
    35641 ttaaaattga ataaagatat agtaaagaag gtatttgcaa taggaatgac accttttgct
    35701 atggaagtag ctataagtat aactcacatg tttacaaata attctctaaa ggtttatggt
    35761 ggagatttag ctattggagc tatgacagca cttacatcta ttttattgat gtttatgatg
    35821 cctgtgtttg gattgaatca aggtatgcaa actataatat catacaatta tggtgcaaaa
    35881 caatatgagc gtgcaaagaa aactttaata ttatctatca tagtgtcagt tgtcatattg
    35941 tcatttggat ttttagtagt acaagttttc ccagaagtat ttgtaggtat atttaataaa
    36001 gattcagatt tgatggatat agcagtaaga ggtataagcc taaatctaat tacattgcct
    36061 ataatgggga tttctattgt aggacctgtg tattttcagt gtataagtaa agttaaacat
    36121 tcaatgtttt taactctttt aagacaattt attttattta taccattaat cattgtactt
    36181 ccaattcaat ttaatttaga tggtgtttgg ttggcacagc cagttgcaga ttttattgct
    36241 atgataatcg tattattatt cttaaaaagg gaatttaaaa caagccgagt gtaagaaatt
    36301 tagaaaataa aattaaattg gaaaataaaa agacttgtct ttataaaatg attaaaatta
    36361 ttttatagag acaagttttt tattttattt aaacggaact atccatactg gtttcttcta
    36421 gtttttttcc aaaagtcatt ttctcaaata tttcttgagg tagaggtttt gaaaaaacat
    36481 atccttgtat catatcacaa ttaatttttt taagataatc catttgcaag attgtttcaa
    36541 caccttctga tatactattc atatttaatt tttttgccaa attaactata gattctatta
    36601 catgattttc agcaatatta tctgcattag gtgagctaaa aaaagcacgg tcaagtttta
    36661 atgtgtcaac ttttatttct tttaacatat tgagtgaaga gtatccactt ccaaagtcat
    36721 ctagtgaaca ttgaaaacct tcttcatgga tttggtctat tatattaatt aatttttgga
    36781 gattttcaaa tacaagtgtt tcagttaatt caatttctaa gagcttagca ggaatgttgt
    36841 atttattacg aagcattctg tatttttcta aaaaatctat attatttaaa ttagcacgtg
    36901 aaaaattaac tgaaacaggt attggagttt ctccattatc tatccatttt cttatcatac
    36961 tacatacttt ttcaaaaaca tagtggtcga gttttgtaat aaaaccattt ttttcaaaga
    37021 aaggaataaa ctcgtctggt ggtataaggc ctttatttgg gtcttgccat cttactaatg
    37081 cttctgcacc tacaatagta ttatctttga ggcttatttt aggctgaaga tatactataa
    37141 attcgttatt atttaatgct tcctccattc tattttccat ttctttttct ttaatcattt
    37201 ttaaacgctc taaatcacta taaaaaacac atgtataaag tggatgattt ccaatgtttc
    37261 ctttattatt ttttcgtgca acatttgcac ggtcttgaat tgaaactaaa ggtagatttg
    37321 ggtcatcaat tttatataca cctatagata gagctataaa atatttacat tcttcatttt
    37381 tattgaaact attaatatca ttggtgatat tttctatgta cttaagaatt tctttttgag
    37441 gaatagtttt aataagtaca ttaaactggt cattagaaac tcgacaaagc aattctcctg
    37501 gttctagata attactaatg acatcatgta tgtactttaa tgttttatct cctgcttcac
    37561 taccaaaaga atcattaata agtttgaatt tctgaatatt tatagatacc aatgaatagc
    37621 tttctgatga agatgactgt ataatttttt tagcttcaat atcaaaacgt gctttactgt
    37681 aacctttagt tacagagtct acataggcga tttttataag ttgtgccctg ttcttttgat
    37741 ttataaacat aatcaatata ataagcaata aaaatagtat aacaattaaa atattgatga
    37801 agattgcttt ttttagaagt aaatcaaact gtgcacttgc tgtttttgtt ggaacaattg
    37861 aaaggaggta taagttttct tcttgtaatg gaagatagtg cattgcctta gaaataccat
    37921 catttaatgt ataatacata gaaccagttt tgttcttttt taagtttatt ttcatttctt
    37981 caagtttatt tttatcaacc tgttttcctt ggtgtttaat catgtcaaaa aaattcatca
    38041 cattttttgg agcatttttg tttgctgaac ttacaataaa atttccatct tggtcgataa
    38101 tttgggaaaa tccttcacca tgaaagcttt ctacacttaa taaatttctc atagtatcaa
    38161 tagtattcca agcaacaaca gctccaacaa ttttatcgcc attgtatagt ggcacagaat
    38221 ataaaattcc atatgtacca gattgtgatt taacaggagt aattgtttct ttgccttgaa
    38281 gggcttttct ataaaagtct tgtcctttaa cattacctgt atctttaagg gcacttacaa
    38341 aatttccatt agaatctata atacctaacc aatcaaattc aaataatttt aatttttttg
    38401 ataagtatct attgacttct ttttcactat cattaatctc aaaataagta tctcccatag
    38461 aatatagtgt cctaaatata cttttacatt tcacattaat tgtagtggaa atactttgtg
    38521 aaacttctac aagatatcgt tctgtttcat tatgtgttac tttatttaga ttcataataa
    38581 aagtgacaca tgttaatgac acgattaaaa ggagtgtcaa tagtaaagta gctattattt
    38641 ttttattttt tgtgttttca aagttcattc ttttgtttca tcctccatcc tttatttgtt
    38701 tacaaataag aattctctca gacatattat accaaatatc ttttcataca aagatattaa
    38761 attttattta tcccacttta catttagctt tatttatgtc ttcttagaga ttaatcaaga
    38821 tacgtttatt gtttaaatct tattttataa tattttgagt aaaagaggtt aaaaaaggaa
    38881 ctgttttcaa aataattttg atacagttcc ttttcagtat agaaaatttt tatagtatta
    38941 gaaagaactt ttagcttatg tatctacata agtattatat ttataaaaga tattttgtta
    39001 caatctaaaa tgtagatgaa attctgtaaa tgccaaattc tctatgacca agactttcag
    39061 ttttggtatg tttaccatta cagacttcta ttatttcatt aaatatttct tgacctatat
    39121 ctgctatttt agcaccatct gttataattc tacctgcatt tatatcgata ttgtctggca
    39181 ttttgttgta tgtatcacta ttcccagtga ttttaataac tggtgaaata gggcttcctg
    39241 ttggagtacc tctaccagtt gaaaagatta caatttgtgc actacctgct accataccag
    39301 tgatagaatc tatatcttga cctggagtat ccataaaata taatcctttt ttatcaggag
    39361 gtacaatatc agcatattca agagcacctt tgaatggctt attgcctgcc ttatacatac
    39421 acccaagtga cttttcttca attgttgaaa gtccaccagc tttattgcct ggagtaggtt
    39481 gaccactacg taaatcttct cccatagcaa ttgctctttt ttctacatca cttacaaatt
    39541 taagaaactt atctttcatt tcttcatcct caaaacgggt agccaacaaa tgttctgcac
    39601 caattacttc tgtagtttca cttagtatgc tacttccacc ttcatctaca agaaggtttg
    39661 atgcaacgcc tattgaaggg tttgaagcta ttccacttgt tgggtcagaa ccaccacatt
    39721 caagtgctaa tgtaatttca ctcataccaa attcaactct tacttctttt gatacttcac
    39781 gagccatttt acttactatt tcagctccct tagaaactgt ttttaatgtt ccgccacatt
    39841 cttgtataac aacgtaatct accttttttc ctgttgtagc tatttcagat gctaattctt
    39901 ttgcttgaat accatcacat ccaagaccaa ctactaaaac tgcggcaaca ttaggatttt
    39961 ttccaaatcc tattaatgtc tttgctgtaa gctctatatc agaaccaatt tgacaacatc
    40021 catgttgatg agggattgct attgctccag gcacaagtga tgctattctt gtagctgtct
    40081 cacttgaaca tacagatgtt ggaataatta aaacatgatt acgaatacca aactgaccat
    40141 tttctcttaa ataacccatt aatttcattt taacttcctc ctatttttta tctccacgac
    40201 cacgtgtact ttcaatgtta tgtacatgaa catagtcacc agtttttatg tcaactgttg
    40261 caattcctat gatttcaccg tatttgtata caacatcacc tttttttaca tcttctgtag
    40321 ccatcttatg aaagacaggt atattatcat ttactatgta agactttcca tcaattgaaa
    40381 ctttttcacc tttaactaaa ggtctgacac atgtaactag attatctttt tcatttgcat
    40441 gaataattgc attcattaat tttacctcct taagtattaa tttacttcaa tatttttatt
    40501 tgttttaaaa atagattttt tctttttttc tcttttatct agataggaaa ctaacattgg
    40561 acaacatatt gctgtaacaa taatagcagc agcaacctgt actgttgaaa cagctgctat
    40621 tgtagctaga gtagggtcta tagctgctaa agcttcagga gtaccagctg catttccggc
    40681 tgttgtacct gtagctgcac ctactgctgg atgttctgca cgtataagtt tcattacaaa
    40741 gtacccaccc atacctgtta ttatagtaac tcctaaacca agtacaactc caggtagtcc
    40801 agcagttata atttgattaa agtttaatgc tgctcctaaa gggaaagcga agaaaggaat
    40861 taataatgtt gtaccaggtg caagaaattc tcgtatatct tcatcaaggt taccaagtat
    40921 aaatccaagt agtattggta taagtgctgc aaatagtgct actataggta catttgcaag
    40981 tccagttact ccaaaagcaa gcattgtaaa aaaaggacca tcatttagag ataagataga
    41041 tattgctcca acatctgtgg agtctccata ttcacctgca agagcagcaa atagacctcc
    41101 atttgaatta gtcatggtag caactatggc aagaggtgta ataccaatta tacctttagg
    41161 tccaataaat ttactaacaa taatacctaa tactgcacca attataaatt ttgttgctgt
    41221 aagtactata cctttagtca atggtttacc agcttgtctg atattgattt gagctccatt
    41281 gcatagacaa aatagagcaa gtatactcat tgcaccagtt ttaaataagg atgttgtgaa
    41341 tcctccaatt tcaagagctt gtggacatac tgtattaaat agtgctccca ataacaaggg
    41401 acagaccata agtcctcctg gtatcttttt cactgatttt aagatgtgca tctagtatca
    41461 ctccctttca tttttatata ggtattataa aagcaattaa tatgccaata tatagagttt
    41521 gtatctttag ttatcatgat tatttttaat aatcgattga aatgctgtag attacttata
    41581 attaaaagta cgattgacga gaatttcact tacaaagatt ctttttatca tataattgta
    41641 ttttttattg aaaacaaata aacgtcttat gtattaaaat taaacataaa acgttttgat
    41701 atatataggt atgtattatt tttaaacatc atcttctatt tcttttaact tacgccatag
    41761 agtggagcga gttatcttta gaatttcaca ggtttttgta gtatttctat tattttcgtt
    41821 ataaatttta tagatatatt ttttttctaa agtttttaaa tctaaattac tgcattcaaa
    41881 atcactatta tctttatcaa ctatattatt tgtatattca ttgctaacct tttctaataa
    41941 aatcgagtca aatgattcca caataacagc cctttccatc ataccttcca attcccttat
    42001 attaccttca tattctcgtt caagaagtgc ctttttaata tttggagtga taattaaagg
    42061 cgttttattg tatttgcttg aatatttatg tataaaaaat tctgataatt ttataatatc
    42121 ttcttttctt tcttttaatg aaggaagata taatgttagt atatttattc taaaataaag
    42181 gtcttgtcta aataaaccat tgcgcatcat attttttaag tctttatttg aagcacagat
    42241 aatttttaca tctataggaa taactttatc accacctatt ctcataactt gtttttcctg
    42301 caataccctc aataatcgac cttgaagttc aagagggatt tcacttattt catctaggaa
    42361 gattgtacct tcatgtgcta gttcgaatac acctgcttta cctttttttc tagcacctgt
    42421 aaatgaacct tcctcataac caaaaaactc actctctatt agagatggag gtatggcagc
    42481 acaatttaca gcaacaaaag gtgcattttt acgcttacta tagttatgta tactttgaca
    42541 aaatagttct ttaccaactc cagattctcc agtaataatc ataggagtat cataacaagc
    42601 atattttttt gcaagttcta tacaatcttt tgtcttttca ctagcatgaa ttatatcatc
    42661 aaaagtgtat ttagcagata gacctttgct taataagctc cttcttattg tatgttcaaa
    42721 agaacttatc tccttgctat cttgaaatgt tgaaacagct ccttgaatct gaccatcaac
    42781 aatgattgga actctatttg taataatttt tgtactccct atattttgta tttcaccaat
    42841 ttgaggttcc atagtctcaa ctacttgtgg aagaactgtg tttgggataa catctacaac
    42901 attatgataa agtgcatttt ctttttttat accaaatatt ttttcagcac tcttattaaa
    42961 taatgttatt ttaaaatttt tatcaactgt tattattcca tcatgtacaa aatctgtcat
    43021 agcttctatc tgtaatcttc ttttttgttc atccttggtt gcttcgagta tttgttctgc
    43081 ttgttgaatg gctctaagta tgttttcttc tctagattcg attaatattc ccttacaatt
    43141 aagtctctta acaatatgtg caacagtggt atctcctata tatgtgttta tacctttctt
    43201 tctgtacttt tctatagcat cataaatttc ttcttctttt tcaatttcaa tcatagttat
    43261 tttcttattc aatatttctt ctataatatc gaaaccgtag atgacattat taaatccaat
    43321 tattccaaat ggttcgttgg aattttttac ctctttgtag ctttttataa tatcataagc
    43381 atctacttta atttcaacta taggtatatt gtaagtagct tttaacatat tgtaagttcc
    43441 acctcggctt atgataattc tagtaccatg attaatactt ttttcagcaa gaggtatacc
    43501 ttcttttaga ttgccaaata caacatcaat atttttatat ttgttttttt taactatgtg
    43561 aattgatttt tcataggttc ctttagtggg agcaataacg agtatttcct tcataataat
    43621 tcctccatat ttcatcaaat aaacttaaat attatcttat gactaaattt tatcagttat
    43681 attttaacat tttactttat atttaattat aaataaagta tttttaaaag gaacattata
    43741 aaagactgta tcaaagttaa cttttagaat tataaagttt catcttttta cagtctttta
    43801 atatataata tctatttatc aaatctatct actttaaata atttcatatt tttattttgt
    43861 ttgccaagat ataattcact taacattata cctcctaata ttgcaaagag tataccattt
    43921 gctccataac ctaagcaata ccatagattg ttatttttat tatctggacc aataaaacct
    43981 aaattatcta aagttgaagc aaaacaacca caatatttat attcaacttc aatgtctttt
    44041 atatccttaa acatactttt caatctttgt tctaaaatat cgtacttttc attggctaaa
    44101 gtttcatttt ctatatcatc aaaacttaca tcttcaccac ctataattaa tcgattgtct
    44161 ttagtagttc ttagataatt atatgggtca cagttatctc taattaaaat gttgtttttc
    44221 caagaagcta tgtttttaag tggtttcgtt gctatattaa aagtatttga cttagttgca
    44281 aaatttcttt ttgtaaataa acttgtattg taccctgtag ctacaattaa ttttttacca
    44341 tgaactttgt atccatacga tacttcagca gtaaccttat catttgataa atctactttt
    44401 tttacttctg tattttcata tacttgaaga ccatttttta aacttacatc aatcaaatgg
    44461 tgactatatt tatatgggtc taattctcgt cctccattct ttgctatcaa tcctgatttt
    44521 aaatcaaagc taaaagggtt tgtggattca tcaatatatt caacatcaaa tccattttct
    44581 tttcttaagt tatattcttc tttgatagcc ttaacttcaa gtttgttggc agtataaagt
    44641 agagtatctc ttttggcata atcacactta tttccatata gctctataaa tgtatctaat
    44701 tcttcaagtg ctgaagtaca aaggttatat gcttttagag catcttttag agtcataacc
    44761 tctgttaaat ctatcaaatt gtcatctaat tcatactgta atagagaagt tgtcacgcta
    44821 gtgcttccat gtgcaatcct tcctttttca agaatgacag actttatatt gtttttagct
    44881 agatagtaag cacaaataca tccagttacg ccaccaccaa caattataac atcagtatca
    44941 atatcatcag taaggtatgg aaattgtctt ggaactttat taatattagt aaaaatagga
    45001 tttcctttta catattcttg attcatatac ttcactccta aaatttatta tgtatgagtg
    45061 tattattttc tatagcaaat aatattatac attttaatta tctagttata tgggtatgta
    45121 tagataaaat gtgataacat tttagtataa aacatatgta taatatattc ataattacct
    45181 tattttaagt aatatagtat ataatgtttg ttaacaagta aaaagattga ataaaagtta
    45241 attaaaaatt taaagtagga ggtaaattta tgctttcaaa aaatatagct tctaaggtat
    45301 tagaaaagtg tctaattact ggaggagatt ttgctgagat ttttgaagaa gacactataa
    45361 ataattctat tagtttaata gataataaag tagaaaatgc aataggtgga agaaattatg
    45421 gtataggaat aagaatattt aaaggattga aaagtatata tgcttataca agtgacaatt
    45481 cattaaatag tctgttggat gtagcataca aagctgctgt tgctttaggt aaattggaag
    45541 atggaaaaag tgtaatatta aatgacagta ttaaaataaa taacatacat aatataaaaa
    45601 tttatccaaa ttcaatagga aatagagata aagtaagtgt tatgaaggtt gcatataaga
    45661 gtgcaaaaga atttagtaat gatatatctc aagtaagtgt tagctatttg gataaagacc
    45721 aaaaaatatt aattgcaaac actgaaggta tatatgttga ggatagaaga gtaagaacca
    45781 gactggggat aagttcaatt gcatctaagg gtaatgaaaa tcaaactgga tttgaaggtc
    45841 ctgggggttg taaagggttt gaaatatttg aagaaataga cccagaatat tatgcaaaag
    45901 aatcagctag agtagcgcat actatgttgc atgctaaaaa ttgtcctgca ggtaatatga
    45961 tggtagcaat agataatgga tttggtggag taatatttca tgaagcttgt ggacattctt
    46021 tggaagctac atcagttgca aaggggaact ctgtatttgc agataaatta ggtcaacaga
    46081 ttgcttccac aaagattaca gctatagatg atggtacaat accaaactac tggggttcta
    46141 tgaatataga tgatgaagga aatccaactc aaaagaatat actgattgaa aatggaattt
    46201 tgaagtctta tatgatagat aaacttaatg gtagacgaat gggaatgaat cctacaggaa
    46261 gttctcgtag acagaactac aaatttgcac caacttcaag gatgactaac acttatattg
    46321 ctgctggaga ggataaacca gaagatatta taaagtcaat accagatgga ctttatgcta
    46381 aaaaaatggg tggtggttct gtaaatcctg taacaggaga gtttaatttt gcagtttcag
    46441 aaggttactt aataaaaaat ggagaaatac aagagccagt tagaggtgct agtttaattg
    46501 gaaaaggtag cgatatactt atgaatatag atatggttgg gaataacgta aaacaagctc
    46561 aggggatgtg tggctcatca tcaggaagta taccaactaa tgtaggccaa cctatgataa
    46621 gggtaaaaga aattactgta ggtggaagat aggagggata attgtggaac ttaaaaattt
    46681 taaagatata ttatttaaaa aggctctaag tgaaggtttt gaagagtgtg aaatatatta
    46741 ttatacagga gaaaatttaa gtataaatat atatgaagga gaagttgaga aatacaatct
    46801 tgataaatct tttggtttat cttttagagg taaggtaaat ggaaagatag gttattctta
    46861 tacagaaatt ttagatgata aagctgttga tatgttgata aaaaatgtaa aagatggagt
    46921 aaacactatt gaaaatgaag atgtacaatt tatatatgaa ggagataagc actataatga
    46981 tgtaaagact tattctaaag agctagaaaa tttagaggca gataagttga ttgatttagc
    47041 tttagaaatg gaaagagaga ctaaagctta ttcagataag gtggtaaatt tatctaaatg
    47101 tactatatct tattctgtat caagtaatgg tatatctaat actaaaggtc ttaatttaag
    47161 caataaaact aatatgctta tagggtttgt agttcctatc atagaagaca atggacaaaa
    47221 atatgatgga ataggatata atatagcaaa ttctattgaa gaaataaaac cttgtgagat
    47281 agcaaaactt ggtgttgata atgctttatc taaagtaggt ggtaagagta ttccatcagg
    47341 taaatataaa actatattgc ttaatgaagc tatggtatct ttgcttagca cattttctgg
    47401 gatatttaat gcagattcag ctcaaaaagg attatcttta ttgaaaaata gagaaggaga
    47461 catgatagca tctcctatag ttacaatagt tgatgaccca cttttagaaa atggtatggc
    47521 atctactcct tttgatgatg aaggagtagc tacatttaaa aaagaagttg ttttaaatgg
    47581 aaagcttata actttacttc ataacttaaa aacggctaat aaggcaggtg taaagactac
    47641 aggaaatgga ataaaatctt catattcatc acctataagc atatatccaa ctaattttta
    47701 tatagagaaa ggagataaat ctttagatga aattataaag gatatagatg aaggattgat
    47761 ggttactagc tttgcaggac ttcattcagg tgcaaattca gtaacaggag acttttcttt
    47821 agctgccaaa ggcttttata tcaaagaagg aaaaaaagta tttccagtgg agcaaattac
    47881 agtagcaggg aactattttg acctgttgaa agatattgaa gctataggag aagatttaga
    47941 atttccaatg agtagtatag gttcaccttc agttgttatt aaagagctat cagtagctgg
    48001 aaaagatgaa taattaaaaa gtaattttgt ggataaaagg tcatgttaat tttaattaat
    48061 atggcttttt attatttaag tagattttat tatctaagtt atatgaaaaa gttgtgatgc
    48121 atacaattaa tatcatacat taaatttaaa ggaggagata ttatgagtga tgcacattat
    48181 gacatgcaca agcgaaatgg atattcaagt gatgagccat atccagagat aaaagtttta
    48241 ggtccaaata agtactatgc agaattattg atggatgact atgccggagt atcaagtgaa
    48301 tttacgagtg taaatcaata tctataccat aattttgatt tagatgaaac gcatagagag
    48361 ttaagtgaaa tgtggataaa tatatctata acagaaatgt tacatatgga gatattagca
    48421 aagactataa gattattggg tggaaatcct gtatatagag gttctacaag ttcttgtggt
    48481 gcatattgga atggtggttt tgtatgttat ggaaattcta tttgtaacag attaaaacta
    48541 gatttgcatt tggagcatgt ggctattaat aattattata aagatataag tcttattgaa
    48601 gacccttata taaaagctat attaaataga ataatcctag atgaaaaact tcatgtaagt
    48661 ttatttgaaa aggcaataga gaagtattgt aaataaattt gaaaatttag ttattcatca
    48721 ttttattcat atatataaaa taaccatcat acattttctt gaagggagtt gctgttgata
    48781 tgtattatgt atatgtgaat gatataaaca tagcagtata tgatttgaat ccgagtgcta
    48841 aaaaaactgt actttttata catggttggc ccttaggaca taagatattt gaatatcaaa
    48901 caaatatatt gccaaaactc ggatatagaa cagtttcaat tgatttaaga ggttttggta
    48961 aatctgatgc aacatcagga ggatatactt atagccaatt agcagacgat atttataagg
    49021 tggtacatgc tattggatta aaagacttta cccttgttgg tttttcaatg ggaggagcaa
    49081 tcgtacttag gtatatgagt ttatttaatg gatatggagt gtcaaaattg gtattagctg
    49141 cagctgctgc accatcattt gtacaaagac ctccagaatt tccatatggt atgacacgtg
    49201 aagatgtaaa taaattgata gcacaagcat gtactgatag accagaaatg gtaaccgatt
    49261 ttggcgaaaa agtatttgca tcaaatccac cagaaagttt tagaagatgg tttaatgata
    49321 ttggttttag tgcatcaggt attggcacta ttggaactgc tgtatctcta agagatgaag
    49381 aattatttaa tgatttaaaa tgtgtaagag tgcctactgg tatatttcat gggaaattag
    49441 atgaaatatg tccgtatgaa tttgcagttt ttatgaatga aaaaatagaa gattcaattt
    49501 tatatacttt tgagtatagt ggtcatgcta tattctatga tgagcttaaa ctatttaatc
    49561 aggaattttt acagttttta gaggaataga tatattttat tatcacttag aaaaagagta
    49621 atattatgtg aaaagattta agctaaattt tatgatgttt tttacactaa acaaataggg
    49681 ttttagaact tgtaactaag ttctaagacc ctattattat atattcctaa aatttgttat
    49741 aatttattcc ttgtcattct taaaaatgta ttaatatatt aacgaattta tattaaattt
    49801 ttgtttatat tccaataatg tcaaactaac cgttttagaa attaaattat atgtgaaaaa
    49861 agatagctta cattatttta ttatggaaaa taatagtaaa tggtacaaaa tttgattttt
    49921 aagatttaaa acttttttaa aaagtgctac aatagaccaa attattactt tctatactcg
    49981 ttaaacagga ggtgggacta tgaaaaaaca taatatttta tttgtatcaa ctgatgacaa
    50041 aataaatata gatatatcaa aacaattgga aaatatattt ggagaatttt gtaatataga
    50101 taacttggta tatgtaaata ggataaatat tgaactgtca agctatgagc ttgtagtatg
    50161 ttcagacaat gatataaagg aatatataca taataatatt gataaaaata tacctattgt
    50221 aatagtacat cgtactataa atattgaaaa tataaatcag ataataagta tagaaaatga
    50281 ttctgatgtt atggttatag atgcttataa agagtcagca gatgaaactg ccaagataat
    50341 tagaaaacta ggattaattc atattaatct aataccatat tatccaggtt gtgataagtc
    50401 taaatgtgag attggaatta ttacgggaag cagaaacagc ataccacaaa acataaagca
    50461 aataattgac ataggtgata aggtaattga tataaataca gttatagaaa tctttacaaa
    50521 actaaatata tctatagata aattacatat tattaaggaa aaatacaatg aagatacagt
    50581 aagtggatat aggtattata caactatgaa taaaaccatg aagagttttt tggagattat
    50641 agatgaaggt attgcttctg ttgataaatt aggaaaattt atatattgca acaaagtatt
    50701 ttctaatcta gttggaatag accaaaatga aattatatct aataacttta tggacttatt
    50761 tagtgataag gttgtcaaaa aaatattttt tcaagaagat gaagttaatg atgaagtagt
    50821 aaatttaaat aacaaaaaac tgataattaa taaagtaaat gtttatgaaa ataatgaacg
    50881 aataaagagt attataagca ttaaaaatat aagtgcaatt caagtgcttg aggacaagat
    50941 tcaaaataaa cttcagtcaa aaggttttgt atcaaagtat acatttgaga gtgttgtagg
    51001 tgagagtaaa ataataaaag aaaaaattaa tattgcaaga aaaatagcaa ctacagactt
    51061 ttctgtgttg atacttggag aaaatggaac aggaaaagaa atatttgccc aggcaataca
    51121 taatgaatct ctaagaaaaa acaagccatt tgttgcagtt aatctatctt ctttgtcaga
    51181 tacacttatt gaaagtgaac tttttggcta tgatgaagga agttttacag gagcaataaa
    51241 aggtggaaaa atgggtatat ttgaaagagc acatacagga acaatttttt tagatgagat
    51301 aggtgatata tctttagatg tacagcagag attgctaaga gtattacagg aaaaagaagt
    51361 tatgagaatg ggcggaagta aaattatacc aatagatgtt agaattatag ctgcaacaaa
    51421 taaagattta aagaaaaaaa ttaaagaagg ttcttttaga gaagatttgt attataggat
    51481 taatgtatta catatagaga tacctagact tagagaacgt aaggaagata tacctcttat
    51541 aagtaagtat tttttagatg aaataaatag caacaaatat tttacagagg aatcaatgca
    51601 agctttaaca ttgtatgaat ggccaggaaa tgtaagagag cttaaaaatt taatttatta
    51661 tattgatact atagttgagg aagatagagt agattacgag catttgccag aacaatttag
    51721 atttgaaaaa aacaatactt tagttaatga aaatttcgat tcaattatct tagatttcaa
    51781 acaatctaat ttctttgagg aaagtatatg tatattgacc agtatagaaa cttggaataa
    51841 taaaaatata ttattaggaa gaaataaact gcaagagatt ttaaaagaaa aagatatagt
    51901 tttaagtgta gaccaaatta gaaaaagaat agataagtta aagagccatg gtttactttt
    51961 atctggagta aaaaaacaag gtagttttat aactgatgaa ggaaagaact ttatatcata
    52021 tgtaaaaatt aagggagtga tataggggac taaaaaggca aaacacccta aaaaaatccc
    52081 tataatggat agaaataaat aaaattatct ttaagattaa gataattcaa aaatattgaa
    52141 taaataatct aagaagatta tttttaataa aacagtagta aatatcaacc ttactactgt
    52201 ttttattttt tgcaagattt attatacaat taaaatttat attttggcac atcaattgct
    52261 acataggaaa aatataaaaa attgtagaac ttggaggatg ttgttatgaa gtcagcttac
    52321 aaaggatatg aagcctatag ttatttagaa aaaggaaaag atatttcatc tattgagatg
    52381 tgtaaaggag ataaaagagt taaagaatac cttattgaat tagatgatat tcaagaagct
    52441 aaggttaaaa gtatagtgga tgaaaaaata tttatatcat tacatgaaca tccagtatta
    52501 tttccagaac acctagaaag agatatattt gaatataata gggaaggtaa acaaagatgt
    52561 gcttatgaag cattatcaag aggatattat gatgctatat ttgataattt aatggatggt
    52621 gtatgtacga taacatcaaa ttcagggtgg aaatgggatg atatattaat agatttaggc
    52681 atgagattat gtgatttagc tcatcaagat tttgtcataa agtgtgaaaa agtagaagat
    52741 atatacagag ctaaaagtga aggtaaagta gcattgatac caacattaga aggtgcagca
    52801 ccaatagaaa atgaacttga tagaatagat atactgtatg gatttggtat aaggttaatg
    52861 ggtataacat acagcgaatc caatgcatta ggttcaggac taaaagaaga gaaagatgga
    52921 ggtcttacaa attttgggaa aaaagctgtt gaaagaatga ataaaattgg aatggcaata
    52981 gattgctctc acgttggagt tcaaactaca cttgatgtaa tagaatatag caaggaccca
    53041 ataatattaa gccatgttgg ggcaagaaat ttatggaaca caaagagact aactccagat
    53101 gaagtattaa tagcatgtgc taaaaaagga ggggttatag gtgtagaagc agcacctcat
    53161 actacaataa cagagaagaa taaagaacat tcaatagagt catttatgga acattttgag
    53221 tatattaaaa atttagtagg aatagaccat gtagcttttg gaccagatac agtatatggc
    53281 gaccatgtaa aattacactc agtactagct gctaaatttg atataaaaaa aataacagga
    53341 acaaaagaac atcccaaagt agaatatgta aaaggtcttg agaacccaac agaaacttca
    53401 aaaaacattg ttagatattt agtaaagcat ggatatagtg atgaggaaat agagaaggta
    53461 ctaggtggaa atatacttag agtactaaaa caggtttgga aatagatata ttagaaatat
    53521 taataaaatt tgaggattta tagggaggtt ttataaatgg attatttaaa attagctaat
    53581 catccacttt tgtggatagc gagtacagta gcagtatcaa tagtagtggt acaatccctt
    53641 atatttgcta taaaatcttg caaagttggt aaaacaatgg gaataacaga taaacaaata
    53701 aagtcagctg ttaagagtag tgctatttca gctattgggc cttcaatgac tatatttgct
    53761 ggaatggtat cgcttatagt aactatgggt gggcctatag catggatgag attatcattt
    53821 ataggttctg taatttttga atcaatgtca gccggatttg gaacagatgc attaggtata
    53881 actttaggtt ctcctgaaat gacaaaactt gcatttacaa atgcagtttg gactatgata
    53941 ttaggttctt taggatggat aatattcaca ttactatttg gacataaact agataagata
    54001 accaatgtta tatctagtgg caagaaatca tttataccaa taatatctct aggagcaatg
    54061 ttgggttcat ttgcatatct aaatgctgat agggtgttgc gttttgataa tggaacaatt
    54121 gcatgtataa gtggaatggc tataatggta atactgtgta tgcttgaaaa gaagaaaaat
    54181 ataaaatggt taagagagtg ggggcttaca atatcaatgt ttagcggaat gataatagct
    54241 tcagtaatat aaggggggag ttttatgagt aaagtaaaat ctatatacaa tgaagaatat
    54301 ttacctttta tgataaggta tggaagacta acactatctt tgggtattat agcagcatta
    54361 gttcctggaa taattttgag ctttggattt ggtattatgc ctccaatatc agcattatta
    54421 gcaagtacaa tggcaattgt cagtatgagt gctccaaatt acataataga accagtttct
    54481 tattcaccaa tcttaggtat accaggaact tatatgagtt ttctttctgg taatatatct
    54541 aatatgaggc taccatgttc aatagcagct caaaaggcag cagaagttga atcaggtaca
    54601 gaagaaggct cgataatatc tacaatagga atagctgtat ctattttagt gaatataagt
    54661 atactaacta taggggtaat tttaggagga agcgtactat ctaaaattcc agctgaagta
    54721 gtagaaaaat taaacttaat tttaccagct ctatttgggt cagtttttgg acaagtattt
    54781 ttacaagata aaaaattagg tctagtagca attgtaatat ctgtattgac tattatatta
    54841 tcaaagcaag gtataatacc acagtctcta gtagttctta tatgtgtatt tggtactata
    54901 ttaattgcaa gagctatgta taaagataag cttagtgact aattacaatg aaataatagt
    54961 gaattttcaa atatgaaatt taataatttg attttcaaat ataaaaatta cattaagatt
    55021 atttaaaaat tggtttttaa ggagggaata ttttgatata tgatttaatc ttaaaaaatg
    55081 gatttataat agatggtaca ggtaatcctg gtttttatgg agatatagca attaaagaca
    55141 acttaatagc aaaaatagat tctaagataa atagcaatac aaataaagag attgattgtt
    55201 gtggaaaagt tataacacct ggatttattg accctcatgt tcatgaagaa atagtagcaa
    55261 tactagatgg taaatttgaa aagtttctaa aacaaggagt tacaacagct ataaatggta
    55321 attgtggaca ttctataaca ccatattctt ctgaaaatgt gtatgaatat atgtataaaa
    55381 atggtctatt acttgaagaa gaaaaaaagt atcttataga taaaaataaa tgttggaata
    55441 attttacaga atattgtgac cttatatcta aaagtggtat ttctgtcaat atgggattct
    55501 tgttggggca tgggactata agatggagtg ttatgggagg ttctaaggat agacctccta
    55561 cagaaaagga aaaaaatgaa attacagata taataaatga tggaatgaaa agtggtgctt
    55621 ttggaatatc tactggattg gcatatatac caagtaagta tgctgatatt gatgaacttg
    55681 ttgatattgc aaggcagatt aaagagtatg atggtatata tacatctcat attagagatt
    55741 acataggaag atataatgca gtaaaagaag ccatagaggt tgggcaaaaa agtggtgcta
    55801 gggttcaagt atctcactta agtccagttg aaatagaagc atttgatgag atattaaagg
    55861 ctaggtataa tggtgttgaa ataatggttg acacagtacc aagaagttct gggcattgta
    55921 tgaagaaaaa aagagtaatt caatttatta tggcaatatc atctagtcta tttgaattag
    55981 gtataaatgg ggtaatggat gctcttagaa atgaagaggg aagaacactt atattaaaag
    56041 aagcatttat acttggagat agggggagta taatacttct aaacactaaa gatattaata
    56101 tggaaaagaa atcaatacgt gaaatagcta cacaaaaagg aatagatgaa gacaagttat
    56161 tactcgattt acttttagat ggagacgaag aacttatctt ttgtttagga ggaatgtata
    56221 gagctgattt cccagataaa ctacatgatg ataaaataat tgataatcca tttgttatgg
    56281 ttggttcaga ttgtttgttt agtgtgggtg gggatatgtc atggtttgaa ctacaaagaa
    56341 gaggagcttt tccaattttc ttcaatatgt acagaaagtc tggtgttaga ttggaagaga
    56401 ttgtaagaag agttacttca ttaccagcta ggcaatttaa aataaaaaat agaggtattc
    56461 ttaaagaagg gttgatagct gatatagcag ttattgacat ggataactat agttattcta
    56521 ggtcagaaga tattgatttt tcaaagccac aattactagc caatggtgtt gaatatgtaa
    56581 ttgtaaatgg aaaaattgcg ttggaaaatg gagagattac tgagaataaa tgtggtgaag
    56641 tattaaaaag ataaggtttt aaaaataata ggatttagaa agtaaataaa tatctaagta
    56701 agtaaagacg aagtttgaga tttatttaaa taaaaatcat gcttcgtttt tatttatagt
    56761 attaatattt attttaataa tcagataata tttatacaaa aaatatttat actttatagt
    56821 gaaaaaatta atatttttaa tcattaaatt atgtaaaaaa ttggataaat agataactaa
    56881 atcatttgag aaaagatttt tagaaataaa aaatgataac taaataaccc ctttaatatt
    56941 tatcaaatag ccagtcataa atattaaaag gggttattta gtttataaaa attatttgta
    57001 ataaagtagg atatattaat aaatatgata gaatatatat tataaattaa atttataaat
    57061 ataagggggg aactttgagt tcttatagat ttcttacatt ataagaacca atactttatg
    57121 cgggagttat taaaagtaac acttatagta atgcttgttt tgataaatgc tttttttgta
    57181 gcttgtgaat ttgctatggt aaaacttcgt agttctagga ttgataccat gataactgaa
    57241 ggtaataata atgcaaaaag atgtaaaata ataaaagaca acttaaattc ctatctttct
    57301 gcatgtcaac ttggtataac actttgttca cttgcattag gttggatggg agaatctaca
    57361 gttaaagagt taattttacc aatagtaagt gtatttaatc ttagtgaaag tattatatat
    57421 actatatcaa tttccatttc ttttttaatt ataacaatga tggaggttgt aataggagag
    57481 ttggttccta aagctttagc actttataat acagaaaaaa taatgttgag tacatctttt
    57541 ttattagtag gattttataa gttaacatat ccaataatat attttttcaa cttaagtact
    57601 gatttatttc ttaaaccatt tggatattca caagctgatg aggttgatga accccataca
    57661 ggtgacgaaa taagactatt agtagaagaa agttataaaa gtggacttat agatgaatca
    57721 gagcaaagat tagttgataa tatttttgaa tttgaagaaa agaaaattag agagataatg
    57781 gttcctagaa ctgatatggt atgtatatat gaaagtgatt ctgaagaaaa gatattagct
    57841 attttaaaag aggaaggtgt tacaagatat ccagtatgca gaaaaaataa agatgatata
    57901 ttaggttttg tacatataag agatttatac aatcaaaaga taaatgaaaa taaaattgaa
    57961 ctagaagaaa tattgagaga tattatatat atatctgaaa atttaactat agataaagct
    58021 cttgagagaa taagaaagga aaaacttcaa cttgctatag ttgtggatga atatggtggt
    58081 acatctggtg tggtaacaat agaagatata ctagaagaga tagttggaga aattcaagat
    58141 gaatttgaca aagaagagac tcatattaag aaaataggag caggttctta cttagttgat
    58201 ggaactgaat ctatcaacta tattaataag tattttggac ttgatataga gcatgatgga
    58261 tttgatagta taggtgggtg gatatcctat atgcttggtt caaatattaa agtaaaccaa
    58321 agtgtaactt ttgaaaatta caattttaca atattagaat tggataaatt gagggttgta
    58381 aaattaatca taaaaagtgt aatataatta tatcaaaaaa tattggagga attgtatgca
    58441 aaaagtagaa ggaattattt ttgacatgga tggagttttg tttgactcag agagaatttc
    58501 tcttgaattt tggatggaga cgtttgaaaa gtatggatat actatgacta aggaaattta
    58561 tacatcagtt atgggaagaa atcgtaaagg aataatagaa ggtcttacag atatatacga
    58621 tagttctgta ccaataatag atttatatga cgaaaaaact aaaaacatga ttgaatttat
    58681 ggagaggaag ggagctccta tcaaattagg agtcaatgaa ctaatctctt ttttaaaaga
    58741 aaatggatac aaaatggctg ttgcaacatc aacaaagaga gaaagagcag taaagagatt
    58801 agctaaggca aatttaaaag attactttga tgctatagtt tgtggagatg atgttgtaaa
    58861 ctctaaacca aaccctgaga tattcctaaa agcagctaaa aagataaatg ttaatcccaa
    58921 aaattgtatt gtcatagagg attcgcctat gggagtcgaa gctgcataca atggtggtat
    58981 aagatgtata aatgtaccag atttaaaaga gccagatgag caaattaaat cacaatcaca
    59041 taagatactt gaaaatttac tggaagttag agaataccta aaaagtttga actctaaaga
    59101 atgtcacaat ctataatata aagtattaat taaataaatt aaatataatt tctttgattt
    59161 agaataaatc catgaatatg agaaaaaata agtataaaca gctaggagga atattcatgg
    59221 ataatgtagg ttctctatta tattttttat ttaatttttt cttgtatggt tttataggtt
    59281 ggataattga aaacttatat agttattata aacaagggca ttttcaagaa gatggatttt
    59341 taaatggtcc atttaaacca atgtatgcaa ttgcaatgtc gattataata gaggtctcaa
    59401 gatttattga ccccaataat atatttgcat tgcttttatt atgtctagta gtgccgacag
    59461 tagtagaata tattacagga atacttatga aagtatattt taataaggtc tattgggatt
    59521 attcagatta taagtacaat agtagaggaa tagtatgtct aaagttttct gtatattgga
    59581 ctatattgac atttattgga gttagatatt ttcaagtgta tatagttgat agcttatata
    59641 gacttataat accttattgg ccaattgttg taactatact tttagtaaca ttgtttgtgg
    59701 atgaaattct tactataaaa tttttgaggg gaaataaaga tatagtagaa agataacttt
    59761 aaaaatataa gttgaattta gattgtagtt aaaagaaagc tatgttaaaa tggtgaaatc
    59821 atttaaaatt agctttcttt tttatttgat aaaattattt tataatatat ctataagttg
    59881 taaagttttt tattaaaatt aaaataaagt gtagaaaatg gggagtgatt tatgatgggt
    59941 aaaataagat ttggtattgt tgggacaagc aatatagcaa atatatttct aagagctgca
    60001 tctagggtta aagactttga attggttgct gtatattcta gaaatttaga aaaagctaga
    60061 gaatttggaa ctctatatgg agcaagtatt ttttttgatg atttagaaca aatggctaaa
    60121 tcgaaggata tagatgctgt atacatagct tctccaaatg cattacattc aaagcaaacc
    60181 attacttgtt taaaacacaa aaaacatgtg ctttgtgaaa agtcgttagc atctaattta
    60241 aaagaagtca aatcaatgat aaaaacagcc aaagataata atgtattgct tatggaagct
    60301 atgagaatta catgtgttcc aaactttaaa gcagttaaag aaaacttata taaaataggg
    60361 aaaataagaa gattttttgg aagctattgt cagtattctt caagatatga taaatataaa
    60421 aatggaatta tagaaaatgc ctttaaaaaa gagttatcaa atggagcttt aatggatata
    60481 ggagtgtatt gtatacatcc tatggtgaat ttatttggcg ctccaaaaac tgtaaaggca
    60541 gtttctcata tacttcaaac tggagtggat ggagaaggtt cagctgtatt tcaatatgat
    60601 gatatggatg cgataattca gtattctaaa gtagctgatt cttatatacc atctgaaata
    60661 caaggagaag agggaagtat aataattgaa aagcttaatc tatttgaaaa agctattatt
    60721 aaatacagag atggaagaga agaagatata tctattccaa aagaaaaagc agaggaaaag
    60781 cctagagaaa tagaaggaat gtattatgaa cttgtagagt ttataagtct tataaataac
    60841 aataaaatag aatcaaatat aaattctcat gaaaattcaa taatagtaat ggaaattatg
    60901 gatgagataa gaagacaaag tagtattgtt tatccagctg atagtatata gtttatatta
    60961 gaaaatataa gaatttataa tatatattct taaataaatt taattttaag ttaaggtaag
    61021 gtgtatactt agccaagtgt taaaatgtca aattataagt atgaaaaagt gctaaaaaga
    61081 aatttatttt tggcgttttt ttcttttttt ttacaatttt gtaacagtat caaaaaaagt
    61141 tttgacgatt ttattacaat tttgtagttg aatatacata tcaaaactaa tatgattaat
    61201 aataacataa atttgaatat ttttagagga gagaaaatat gagaaaattg atatacttta
    61261 ttacaccttt tataataggc gtagtatttt tatttgggtt agacaaattt cttgattcta
    61321 aaactgatga acttttgagg gagaaaaatc tacttccaat tatggatgat actttaagtg
    61381 atataaaaga taaaggggtt acagcaaata atcatttttt aagagaaaag gatattatga
    61441 ttttggggtc atcagaactt agtaattcaa caaaacaaca tccaaagtac tattttaata
    61501 caaataggag taaaaataag gtgtttgcaa ttgggagagc ctatactcag acattacaag
    61561 atgctgcaat attaggaagt atgaatccta atattgataa taagaaagtt gtcttgttaa
    61621 tttctatgca atggtttatg gaaaaagacg gagtcacaag tcaccattat cagtctagat
    61681 tttcaccaat acaattttat cgatttttag ataatccaaa aatatctaaa caaaataaga
    61741 ttgaatatgc aaaaaaatca agtaagttat tatggggaag tgatgagtat aaagcagaag
    61801 cattatatgc taagctatat gagcctaaga catttcctga aaaagctgaa aaggtgcttt
    61861 tagagcctta ttttcaagga agaaagtact gtatagctct taaagaaaag ggtattcttt
    61921 ataaacgatt aattaagcta gataaaaaga gagcaacaaa aagaaaaaga ccaataaatt
    61981 ggtcatatga gagaaagaaa gccattgaag atgctaaaaa aagagttggt aaaaatccac
    62041 taaatattga taagtactat tataaagagc attttaaaga tggtatagag caatacaaag
    62101 gaagagacaa agatgtaaat ttattaacat ctaaggagtt tgaaaattat aaactgatgc
    62161 taaatgtatg tactgactta ggtattaagc cagttgttgt attaatccca agtatggata
    62221 aattctataa tttgactggt atttctgaaa aagaaagaaa tcagtactac gataaagcac
    62281 aaaaaatagc agaaagcaaa ggctttgaag ttctaaacct taaagataaa gggtcagata
    62341 agtattattt aagggatgta atgcatcttg gtacgaaagg atgggtagat gtctgtgaga
    62401 gattatttaa aatatttaaa gaacaataaa gatttgttaa ctagtatttg tttaactatg
    62461 gttataatat tggcgatagg agttctaaca tttactccat ttaaagaatt gccatttatt
    62521 tataacggat tttaaaggag cattcttata tgaaaattat tgaaggaata aaaaaatatt
    62581 caaatacaga tagaacagca ctaatgtgta atggagataa actttcttat aaagatttaa
    62641 atgaatattc agatgctata tcagtatttc taaaggatgt atacaaagaa gaagatactc
    62701 ctatagtaat ttatggaaat aaagaaaaca tgataatggc atgtatgata ggagctttaa
    62761 aatcaggtag agcgtatgtg cctcttgata ttagttttcc aattgataga gtttttgaag
    62821 tcactaaaga gataaaacca aaggtattat ttaactttag tgatgaaaga aattttggag
    62881 atatcaatgt aattgatatg gataaattaa attatataat aaatgaatat cagggaaaat
    62941 cattagataa agaaaactgg gtaaaagatg atgaaaatgc atatatacta tttacttcag
    63001 gaagtacagg aaagccaaaa ggggttcaaa taagttcaaa caatttagat agcttttcag
    63061 attggataag cccatatcta aacatagatg gaagtgaaaa agtaataatg aaccaaccag
    63121 catattcttt tgacctttca gttacaacaa tataccctgg tcttatccat ggagctacat
    63181 tattttcaat atcaaaagat gtattagcag actataaaga actatttaga caatttagta
    63241 tctcagatat agctgtatgg gtgtcaactc cttcttttgc aggagtatgt ataactgaaa
    63301 aagagtttaa tagtaaaatg cttcctaacc ttgagtcaat gatattcata ggagaagcac
    63361 tttcaaaaaa tcttactaaa gaacttatga gtagatttcc aaacacaaga attatcaatg
    63421 gatatggacc aaccgaggct actgttggtg taagtgtaaa tgatatgact caaaaggcta
    63481 tagatgatga aaaaagtctt ccagttggat accctatgtc aaattgtaaa ataaaaatac
    63541 ttgatgaaga tggaaatgag cttaaagaaa atgaaaaggg tgaaattata ataattggac
    63601 catcagtttc taaaggttac ttcaataata aagaaaagac tgatgaagta tttttctatg
    63661 atgaaataga tggtgtaaag tggagagctt ataaaactgg agatatggga tatcttttag
    63721 atggaaatat atattattgt ggaagaaaag attttcagat taaattaaat ggatttagaa
    63781 ttgaaataga agatatagaa aataatttga gaaaagtaca taatgtaaaa aatgcagtag
    63841 ttttaccagt atataaggac gaaaaaattg cttacttaaa aggtattgtt gagttaaatg
    63901 aaaagaatga tttaagtaat attaaaaatg ggatgataat aaaaaaggaa cttggaaagt
    63961 atataccttc atatatgatt ccaagaaata tttcaataat ctctgagttt ccaacaaata
    64021 tcaatggtaa aatagacaga aagaaactta tggaggaaat ttaatgattt tttcacaata
    64081 tggagattat ttttatcttt atatattatt attaacatca ataccagcag taattttagg
    64141 tctaatgggc aagaatataa agtattatgg tatgttggca agtttgttta tgatattctt
    64201 aatagtagga attgatgtcc aactaaagta cttggtaata tttattattc ttgaagtaat
    64261 aatagttaaa ggatatgaat atgtaagaag aaaaactaaa aataaataca tatattgggg
    64321 attcttgttt gcatcaatgc tcccaataat aataaataaa atatctccag ttacttcttt
    64381 tggaataatt ggatttattg gaatatcata cttaaatttc agaactatac aaatggttat
    64441 tgaaatttat gatggagcta taaaagaagt taaaatttca aagatgcttt attttatgtt
    64501 attttttcca actttaagtt ctggacctat tgataggtca agaagatttg aacaggactt
    64561 ggaaaaacaa atctctagaa aagagtatat agaagaatac ttactgccag gaataaaaaa
    64621 tattgtcatg ggagtaggtt ataagtttgt tatagcattt ttgataaata catattgggt
    64681 atcaagaata cctaaagata tgagttttat aaatatttta agttatatgt acgcatatag
    64741 tttatacctg ttctttgatt ttgcgggata tagtttattt gctataggta cagggtacat
    64801 atttggaata caagtaccta taaactttga caagccattt atcagcaaag atatgaaaga
    64861 gttctggaca agatggcata taagtctttc aagatggttt ggagattata ttttttctag
    64921 atttgttatg tcatcaatga gaaagaaaag atttaagaaa aggactactg ctgctcatgt
    64981 ggctcagatg ataaccatga taacaatggg attttggcat ggtctaactt ggtattatgt
    65041 tgcttatggt gtataccaag gattggcact tgtgttaact gatatatatc agcgaaaatc
    65101 taaattttat aaaaaacata aaaaagataa atggttcgag agagtgcaga ttttcattac
    65161 attccatatt gtgtgttttg gattgctgat attctcaggt tatttagctt aattttaagg
    65221 aggaaaattt atgcaagaaa cagttataga aatatttgaa gatgtattag gaactgatga
    65281 gataagagaa gatttagacc ttaatttatt tgagacggaa cttttagact cattagctat
    65341 aattgaagtt ttacttgaaa ttgaaaatag attagggata gagcttcaac caactgattt
    65401 agagagaaaa gatatgtcta ctgtaaataa tttagtaaaa ttcttggaga caagaaaata
    65461 aattagtagt tagactttaa atattaattt ataaaataaa attttacaaa gtccatctga
    65521 tactaatatt tgatggactt ttttaatgat aatacaaagt cttttgaaaa taactttaat
    65581 taagtaaaaa atttaataca taaatatgat ttcataaatc ttaggtatca ttgtaatatt
    65641 ataggagaaa aatatattat atttaggagg aaaatgaatg tctttaaatt cgatagatag
    65701 aaaaaaagaa atacttaaat tattagattc aaaagggaag gtaaacacta aagaattagt
    65761 aaaaagatta gaagtatcat cagaaacaat aagaagatat ttggaagaat tagaaaatga
    65821 aaataaatta aaaaaggtat atggtggtgc tataaaaata aattatggag tgattgaacc
    65881 agaacatata aagagaaaca atactaacct agataaaaag catagtattg ctaaatatgc
    65941 agctaaattt gtaaatgaca atgagtcaat tatcatagat gaaggtacta ccaatttgca
    66001 gattgtagat tatataatat ctgtaaacaa tttaaaaatt attacaaact cttatccagt
    66061 tctatcaaaa ttgatttctt atgagaatca aggtttgttt gatggagaag ttatatttat
    66121 tggtggaaaa gtaaatttaa aacaccaaag gacagcatgt ccaatgtcaa tagatactat
    66181 gaaaaactta tacgtagata aagcttttat atctagtgaa ggtatacttg atagttttgg
    66241 aattagtagt atagaccaaa ataaggcatt gttgtcaaaa gaatatataa aaaattcaaa
    66301 ggaaagtttt gtattatgtg atagttctaa aataggaatt gctagtatgt ataagatagc
    66361 agatttagag gaattagatt ttgttatttg tgatgtagaa cctccgaatg aatggaagga
    66421 taagttaaat gagataaata taacatggat agaagcaaaa taaaccctta gttttatata
    66481 atacaactat gctcaataca actaaattca taaaatatag tcagttcata gattaagatt
    66541 agaaagtaaa ttttagattg taacttagga ttttatggga atgtgataca aaataaaaac
    66601 aactaaatac aactaaaaac agaaatttaa tatatattta acctaaatat gatgtataat
    66661 taacatatga aagttatact ttaaaagtaa aaacaattaa aaacacaaaa attctaaaaa
    66721 gaatctatgg aggctataaa tatgaaaaag atatatggag aaaaaataaa agcagtagta
    66781 ttcgattggg ctggaacaac agtagattat ggatgttttg cacctcttaa tgtatttata
    66841 gagatattta aaagaagagg tatagatgta acaatggaag aagcaagaaa acctatggga
    66901 aaattaaaaa tagaccatat aagagaaatg tgtgaaatgg ataggataaa aaatctttgg
    66961 tcagataagt ttggtaaagt gccaactgaa gatgatgtaa atgaacttta tgctgaattt
    67021 gagacaatgt tatttgagac attagaagat tatacgactc caattcctca tgttgttgaa
    67081 actattgaaa agttgagaga aaatggatta aaaataggtt ctacaacggg ttatacaaga
    67141 gagatgatga acatagttga accaaatgca gcaaagaaag gatactcacc cgattttctt
    67201 gtaacaccat cagaagtatc tcaaggaaga ccgtatcctt ggatgtgcta taaaaatgct
    67261 gaagctttag gggtgtctcc tatgagttct atggtaaaag taggagatac aataagtgat
    67321 gtaaaagaag gcgtaaatgc aggaatgtgg agtgttgctg taataaaagg ttcaagtgag
    67381 ttagggctta cacaagaaga agtagagaac atggataagg aagaattaaa agctaagatg
    67441 agtatagttt caaagaaatt taaagaggca ggtgcacatt ttgtaataga aactatggct
    67501 gagttagaag atatactaat aaaaatagag aatgaaacta ttaaatcaga ttttgtacca
    67561 gaaaatgatt acatattact tacaccagga ccactatcta ctactaaatc agtaagagca
    67621 tctatgttaa aagattggtg tacttgggat gttgaatata ataacctagt acaagatgtt
    67681 agaagaagat tagtatctct agcaacccaa aatacagata aatacacaag tgtattaatg
    67741 caaggaagtg ggactttttc agtagaagct ataataggaa gtactatttc aaaagatggt
    67801 aaacttcttg taattgcaaa tggagcatat ggaaagagaa tgaaagatat atgtaattat
    67861 cttaacatag aatttgttga ctgcacattt aaagatatag aagcagtgga tttaaatgta
    67921 gtagaaaatt tattaaaaga aaacaaggat ataacacata tatcaatggt tcactgtgaa
    67981 actactacag gtagattaaa tcctatacaa gaggtaggga aacttgcaaa agaatataac
    68041 aaaatttata tagttgatgc tatgagtagt tttgggggaa ttgagattga tgttgaagat
    68101 tttaatatag attttttagt tagtagttct aacaaatgta tacaaggagt acctggattt
    68161 ggttttataa tagctaataa agaggaatta tctaaatgta aaggtatagc taaatcatta
    68221 tctcttgatg tgtatgcgca atgggatact atggagaaaa ataatggtaa atggagattt
    68281 acttcaccta cacatgttgt aagagctttt tatcaagctt tattagaatt ggaagaagaa
    68341 ggttctgttg aaaaaagata tgctagatat aaagaaaatc agtttacaat agcttcaaga
    68401 ttaaaatctt taggctttga tactttggtg aatgataatg ctcaatcacc tgtaataaca
    68461 actttcttat atcctaaaaa tgcaaagttt gaatttatgg aattttatac ttatttaaaa
    68521 gataatggat ttgttatcta tccaggtaaa ttgactgata tagatacatt tagaataggt
    68581 agcataggtg aagtttatcc aactgatatg gagagactag ctgatgtaat agaaaaattt
    68641 atcaatagat agaagaagat agtgtcttgt aggttacaga atagtgcgga aagcccactc
    68701 ctttaggtgt gtgagatgat agcacaaaca gtgtataaaa agtattgaca gtagaattta
    68761 aagacttata ttttagaagt ttatacaatg aatatataaa gattgagtaa tagggatata
    68821 ttttatttaa accacaatct aagaaattag atttatagtt taaataaagc atttccctat
    68881 tatttttatg cctatttata gaaaataaat gatagttgct ttattaagta ttattatcat
    68941 acttgacaac gtaacaatgt tttgttatat taggtttaaa gataaaatac ggtaaagaaa
    69001 ggatatcatt atgaatgaag aattaagttc actaagattt gatggtgttg gaaaatgtaa
    69061 aggtggaatt tttgataatg ttaatatatc aggaacaggc aaaatagaag gaagtgtaaa
    69121 atgtagtaaa tttgattctt ctggttcagc aaaagttttt gggacaacag aatgtaatga
    69181 attttttaca tctggtttaa gtaaagtaga aggaaacata ctggcatcaa aagttgagat
    69241 atcgggactt cttagatgta caggaaatat taattctgtt gaaattgata ctagtggaat
    69301 tattaatgta gaaggaagta taaaatctga tattattcat ggagaaggat atttaaaagc
    69361 aaatgagaat atagattgtg aaaatatcaa tttaagtgga atcttggagt gtaatggatt
    69421 tttgaattgt gaagaagtta atattagttt aaatggaact tctaatttta atgaagttgg
    69481 agcaagtagt ataaatataa aaaaggggca tggagattat tgcaaaaaat ttcgtatgct
    69541 agaaaaaaag catatcaact ttgaaaaagt gtcttcaaat ttgataagtt taggtctatt
    69601 atcaattaga aagtatacag aaagtaaatt gtttgcaaat attatagaag cagatgaaat
    69661 aagcttagaa aatagtgaag tcaaagttgt aagaggaaaa aatattaaaa taggcaaggg
    69721 atgttatgta gaaagtttgg agtacagtga aagtatagag attgatgaag attcaatagt
    69781 tggtgaaata aagaatataa gtgaaaaaat aaaattaaag aaggataagt aataaatagg
    69841 tttaaaaata aaatttaaaa tgaggtaata atatggaaaa agggtctata aaaatactag
    69901 gagaaggctt tataagtagt ggtgagtatg aaaatataaa aatcgtggga agttctaaat
    69961 caaaaggaaa tgttaaaagt aacgaagtaa aagtccttgg agatgcaaaa tttgaaggtg
    70021 acatcaatat aaaaaatttt gttgttaacg gaaaaactat tataagaggc aatcttaaag
    70081 cagagcgtgt aagagtgaat ggtcaactta atatagaggg agatgcagaa atagatgact
    70141 tagttataac tgctcaacag aaagtggatg gcaaacttaa atgtaataat gttacaataa
    70201 gaggacaatt aagtgtaaat gaaaatatgt atgcacaaga tataaaaatc tatggcgaaa
    70261 tgagaaataa atcaaatata gaatgtgaag atataaaggt atatggagta ataaaatgtg
    70321 atggtctttt aaatggagaa aatatatatg tttattcagg aggaggttct tattgtaaag
    70381 agataggggc aactaatata aaaataggaa gaagcaaaga tgctttttca ctaatcaaaa
    70441 tcattaatat tttttcagga aagtttaaat gtaatttgat agagggagat actattgaat
    70501 tagaagatgc atcaataaaa gatatacgag gcaaaagcat atctctagta gataattgtg
    70561 acgttggaaa tattgaatac agtgataatt tatcagtttc agataattct actgtaaaaa
    70621 acagtataaa ggtgggctag aaaagttatg gaagaattaa tatctaagaa agatttattg
    70681 agcaaaacta atatatctta tggtcaatta tatagatgga aaagaaaaaa cataatacca
    70741 gaggaatggt ttataaaaaa atcagctttt acaggtcaag agactttctt tccaagagat
    70801 aaaatactag aaagaataga gttaatattg tctatgaaag aagagacttc tcttgatgat
    70861 attgcaaata tgtttatgaa aaaggatatt aataaagaat ttgacattga ttttattctc
    70921 agtaaagaag ttatatgtaa ttataccaaa gaaatatttc aaaatttata taaaaaagag
    70981 caaagcatag gtaaaaaaga actgcttata ttgagcataa tagagaagtt tttagttaaa
    71041 tctataataa cttttgaaga gttaaaattg atagtgaata taatagaaga aaattttaca
    71101 tcaatataca atgaaagtgg aaagatttat ttgtttagaa agtttggagt tccattcgta
    71161 gtaggatgtt tggattataa aaaagtaaag tttgaaaaag atgtagttaa gattattgag
    71221 gttgacttga caaaagaaat aaatgatata agtataaagt tatcatagtg tattatctta
    71281 tataatgtat tataataata tacttaaaat acactttatt taaatattta gtttaaagat
    71341 gagattttat gtgagtgtgt aaaagttaaa gatagattta agtaggttat agggattagt
    71401 aaacaataaa atgaaccatg atgaactact ataaattgta tttaaactac attttctact
    71461 tatagtaata tcaatggttc attttattgt tattaagata atacagtatt tataaaaata
    71521 cttgatataa atatagtaaa ttgtttaaat acaatgatta ccttagttta ttcaaataat
    71581 gagtttttaa aatctaagaa atatccttgt ggatgaagac atacaggaca agcttttgga
    71641 gcctctttac ctatatgtat atggccacaa tgtgtacata tccattgtat atcttcattt
    71701 cttctgaata aagtaccttc ttctaaatca gtagcatatc taccaaatct atcaccatga
    71761 actttttcta tttcagctat attttcaaat aacttagcta tagattcaaa tccttcttca
    71821 cgtgctgttt ttccaaagtt tttatataca tcatcccact cttgaagctc attatgttgt
    71881 gcagctttaa ggtgttgtgc tgtcttgtca tataaatcta cagggtatgc tcctgatata
    71941 cttatatttt caccagcaaa ttcttttaat ttagaaaaga attgttttgc atgtgatttt
    72001 tcttggtcag cagtgtaatt aaataaagac tctattatat ataatccttc tttttttgct
    72061 acagatgcag aaatattgta tctatttcta gcttgactct cacctgcaaa agctcttaat
    72121 aaattttctt tagttttact atcttttaaa ttcatattct acctctctat cacaataaat
    72181 ttttacaata tttgattctt tttatttatt attccaatag gagatataat tatgctcaat
    72241 ttagtcagca tttttaaaat tatcattaat tttttttaaa attctaagaa attcttgttt
    72301 ttcattttct gtaatattat gatatgccgt ctctttaact tgtgttgaga tgctattaaa
    72361 agtatcttct ataagcagtg ccttttttgt aagctttata tacgtgatac gtttgtcatt
    72421 tgtacatttt tgtctttcta aatatcctag gtttataagt ttattaacca acactgtaac
    72481 agtggattta tcttttccta ttttagctgc aatttctttc attgtaagta ttccattatt
    72541 ttcataaagt gcagttaaaa tatttccatg agtaggtatt aactcaccta aaccattttt
    72601 actgagttta ttttcaatga atttaatcat actagccttt gttttactta tgaaatgtac
    72661 aatatattta tcttccataa attattctcc aatctttaat ctatttaaat tagtttgaca
    72721 taaaactatt tataaactat aattagttta acataaaact aaatgtattg ggaggaaatt
    72781 tatgaataaa aaatttaaat cactatatat tacagaagaa gaaggaaatt ttagaagaaa
    72841 tatagttgaa agagaagtgg atacattgcc agaaggcgaa gttttaataa aagtaaaata
    72901 ttcttcttta aattacaagg atgcactttc tgcaaatggt aataagggtg ttacgagaaa
    72961 gtatcctcat acaccaggaa ttgatgcatc tggtatagta gaatctagta gttgtgatga
    73021 ttttaaaatt ggagaagaag ttttagtaac aggttatgac ttgggaatga atacttctgg
    73081 tggtttttca gaatacataa gagttccttc tagttgggta gttaaacttc ctaaaaatct
    73141 ttcactaaaa gaagcaatgg attatggtac agcagggttt acagcagctt tatctgtgta
    73201 taaatttata gattctgtag acaagaatat gggagatgta ttagtcactg gtggtactgg
    73261 aggagttgct gtaattgcaa ctaaaatatt gattaaatta ggttattcag ttgtagtttc
    73321 aacaggaaaa ttagaagaac aaaaagaagt attactaaac ttaggtgtta aagatgttat
    73381 acataggtca gaagtggatg ataactcagg aagacctctg cttagaccaa gatgggctgg
    73441 agtaatagat acagtaggag gaaatactct agcaacagca ataaagacaa ctaattattg
    73501 tggagcagta acaacttgtg gtaatgcagg aggagttgat tttacaagtt cagtatatcc
    73561 atttatctta aagggaatta ctttatatgg tatagattct gtggattgtc caatgaactt
    73621 aagattaaaa atatgggatt tattatcaaa tgaatggaaa ttagatgatt tagatgatat
    73681 ggtaaatgta gtatcattgg aagagttaaa tgatagtata gattcaataa tggcaggaaa
    73741 acatgttgga agaacagtag ttgatttaga aaaaatatag gtgaataaat ttataattag
    73801 gattataggt tttaagcaaa aatgagatac ttgaaattta cttatgagta tctcattttt
    73861 ttatgtaaaa agatttatgt agatgtttgt gtaaaaagat tattcatgaa caattaattc
    73921 aaatacatct ggtcttgaat agtgaccttc tgaatcaaaa tctagtctac taagtactat
    73981 tttttctagg tctaaatcag ctattagcat ttcttcttta ttgaaaatag gacctgctac
    74041 atattttcca aaagggtcaa ctatacaact tcctcctgga cacataattt ctggttctgc
    74101 atctagctcc ttatagtagt taaggtcagt tgggtacata tttttttcaa catattgatt
    74161 gcatccaatt acaaaacatc ttccttctaa agcaatatgc ttcatagttg cttgccactc
    74221 ttctcttgaa tctgcagtag gggctatgta aagttttaca cccttagcat aaagagctgt
    74281 tctagctaat ggcatataat tttcccaaca aatcaacgaa cccatttttc catatggagt
    74341 atcaactact gtaagagtac ttccatctcc ttctccccaa atacatcttt ctgttcctgt
    74401 aggtttaagt tttctgtgtt taccaattag cttaccttct ggagagaaaa ataagtttgt
    74461 gcaataaagg gtacaattta tatcattacc atctctttct gttataccca ttgatagata
    74521 tactcctgct tcttgtgctg cttttcctaa taaatctgtt gtagcactag gaactggtac
    74581 agaattatca tagtatcttt tccaatcttc tctaccttcc attgttctac ttccaacaac
    74641 aaatccaaat gaaagacctc ttggatatgc aggtatgaat gcttcaggga aaactacgat
    74701 atttgcccct tttctaccag cttctttaat taatcctaat gctttttcaa cagttttttc
    74761 taaatccatt atgactggtg acgcctggac aacagcaatt cttacatttt tattttcctt
    74821 gctcataaaa aacctcctaa aaaatattta aattttttgc attgaataga ttacatgaga
    74881 tgttatttga gaactaagat acttatattg tgaataataa tgtaactgta tatttaaaat
    74941 aatacatcat gatttaaaaa attacaattg tacagatata attgagttta gatatttaaa
    75001 tttaacaact tataatattt tttcaattag tataaatcct attaatttgt cttatttaca
    75061 atgaatagta tttacttctt ggcaaacaat aattaaaaat aaaactttta tatgattaaa
    75121 ctctaaagaa aaagtttata aagaagataa tataattaag cagaaaataa tgaaaaaaat
    75181 ttattaaagt agacaacgta aggagaattt tatgaaagca aaaatttatt acaatggaaa
    75241 tatcatcaca atggaagatt caatatgtgg agatgctatt cttataaaag acaaaataat
    75301 aaaaaagata ggaacaaaag aagaagtatt tgctttgaaa aataaagata cagaaattat
    75361 agatttacaa ggtaagacat tgatgccatc ttttatagat tcacatagtc acttgatagc
    75421 ttttgctact actctaaagc tagttccttt agaagatgca accagtttta aagacatagt
    75481 aaaaaaaata caggatttca aagagtcgaa taatataaaa aaaggagact ggataattgg
    75541 attttcatat gataataatt ttttagaaga aaataagcat ccagataaga gtgtactcga
    75601 tagtgcatct tcagaaaatc caatactaat ttcacatgct tctggtcata tgggagttgc
    75661 aaatacattg gggttaaaac agcttggtgt taccaatgaa acacgtgacc cagaaggtgg
    75721 acatataggt agagtagaag gcagtgaaga accaaatgga tatttagaag aaaatgcatt
    75781 ttttaatgta gcatctaaaa taaaacaacc atcatcaaat gagattttta attcaattga
    75841 aaaagcacag aacatatatc taagctatgg tattacaaca gctcaagaag gtttaatgga
    75901 agaaaatcaa tttaacattt taaaagcaat ggcaaatcaa aataaattaa aaatggatgt
    75961 tgtaggatat gtaaatttga aaaaaagtaa gtctgtagta gataataata gggagtttat
    76021 aaaaaaatat ataaatagat ttaaaatagg aggttataag attttcttag atggttctcc
    76081 tcaaggtaag acagcatggt tgagtagacc atatgaaaat tcagatgatg gttattgtgg
    76141 atatcctata tacaaagatg aagaagtaga aaagtttata gatatttcac taaaagaaaa
    76201 gatgcaactc ttaactcatt gtaatggaga tgcagcagca gaccagttga tagatgcgtt
    76261 tgagaaagtt ttaaacttaa aagagcaaag tagtgaaaat aatataagac cagttatgat
    76321 acatgctcaa acagtaagag cagaccagat tgatgatatg aaagtaataa atatgatacc
    76381 ttcatacttt gtagctcaca catattattg gggtgatatt catatcaaaa accttggaga
    76441 agatagagcg tttaagatta gcccacttaa aacaactata gaaaagggat taatttacac
    76501 tcttcatcag gatacaccag taatagcacc taatatgctg gaaacagtat ggtgtgctgt
    76561 caatagaatt acaaaaaaag gtatacaaat aggagaaaat gaaaagataa gcccattaga
    76621 tgctttaaag ggtgttacta taaatgcagc atatcaatat tttgaagaag ataaaaaagg
    76681 ttcaattaaa gaagggaaat tagctaattt gataatatta gatgaaaacc cacttacaat
    76741 cgaccctatg aaaataaaag atattaaagt attgcagact ataagagaag gagaagtatt
    76801 gtattctttg aagtagatga aagttagata ttttataatc tataaaaaat agttttatat
    76861 aataagttag gtagaattaa ataagattac agttaaatca acaattatat ttttattaaa
    76921 ttttaattat tgtattgaag atttataagt ataattttat tgattctacc tttttaaata
    76981 actatcgatt tattaaagtt atctatgtac tatattaaac aattaagtag ttattaattg
    77041 cacttattag tttattaaaa aactatgtat attactttgc agtaagactt tggaactaaa
    77101 tctataatag caaatttaaa tttattaaat agattacctt ataacatttc atataaaata
    77161 tattgtgaat ctcagaaaat tactattttt ctttgaatat tttttgtaag cagttctaaa
    77221 agattcaatt tcatacctat tacttgaatc attcatcaaa ataattctaa tttaaaaaat
    77281 aattctatcc aaataataga tatataggac tatgttataa tataaaaaaa tttatataaa
    77341 agttaataac tatacaagat tgataaagaa aaagtcaaaa tagataattg attagcaaaa
    77401 tagatataat tataatgaag ttaaatctag caatattctc ctaaaattaa atttcattta
    77461 tttaattaaa tataatttga caatgggcaa aaaagtgagt aaaatataaa taaaataaaa
    77521 ataacaggtt cggataaaga aaaaggtttc ttaacctcaa gcataaagta tattatctaa
    77581 gttatttgag attaagagat aaatccaatc ttaggtactg aggaggaaaa aatgcttgat
    77641 ataaaaagaa taagagaaaa tttagattgt ataaaaaaag caatggaaag aaggggcgaa
    77701 aaagacttta accttgatga agtagttaag ttagatgatg aaagaagaaa gattcttcaa
    77761 gaagttgaag ttatgaaaaa tgaattaaat acagcatcta aaaatatacc aaatcttata
    77821 aaagaaggta aagatgtaga aaatgaaaag attaaactaa aagagttatc tgataaaatt
    77881 aaggtaatag accaaaatct taaagaagta gaagataaga tggaatacct attaatgaga
    77941 ataccaaatg taccacatcc agaagtacca caaggtgaaa ctgatgaaga taatgttgaa
    78001 gtaagaactt ggggaaagac tactaccttt gattttgaat ctaaggctca ttgggaaatt
    78061 ggaacagaat taggtatact tgattttgaa acagctagta aaataactgg ttcaagattt
    78121 actctttaca aaggattagg tgctagatta gagagagcat tattaaattt ttacttagac
    78181 acgaatacaa aagtaaatgg atatacagaa gttattccac catttatggc aaatagaaat
    78241 agttttttag gtacaggaca gttacctaag tttgaagaag atatgtttaa aatagaaggt
    78301 ctggactatt ttatgattcc aacatcagaa gttcctttaa ctaatataca tgctaatgaa
    78361 atacttaaat ttgaacaatt accaataaat tatacagctt atactccatg ttttaggtca
    78421 gaagctggtt ctgctggaag agatacaaga ggtttagtaa gacagcatca gtttaacaaa
    78481 gtagaaatgg ttaaaatagt tgcaccagaa gaatcttaca atgagttaga aaagcttact
    78541 aacaatgcgg aaactatgct acaattattg aatctgcctt atagagtagt aaagatatgt
    78601 acaggtgatt taggatttac ggcttctttt aaatatgatg tagaagtttg gatgccaagt
    78661 tacaataggt atgttgagat ttcatcttgt tcaaactgcg aagatttcca agctagaaga
    78721 gcaggaataa gatttaaaag agataaagat tctaaaactg aatatgtaca cacattaaat
    78781 ggctctgggt tagctattgg aagaagtgtt gcagttatat tagaaaatta tcaacaagaa
    78841 gatggttctg tggttgttcc tgaagtttta agagcatata tgggagtttc tgttattaaa
    78901 taagagttaa attatgtatt tttaagcaat acaataatat agaggtaata aaaaataatt
    78961 aatataaaag tgatacttct aatatagaag taataaaaaa atagttaata taaaagtgat
    79021 acaataatat agaagtaata aaaaaatagt taatataaaa gtgatacaat aataatagaa
    79081 gtaataaaaa aatagttaat ataaaagtga tacaataata atagaagtaa taaaaaaaaa
    79141 taattaatat aaaaatgtgt acaaactaat gaatattgat atagtaagct atcatatgaa
    79201 agagtatgta cacatttttt ttactaattt ttcacaatat gaacataaat aatttacagg
    79261 aaaggaatct tttatgaaaa ttcaaaatac tgagtgggga tatattgaat ggaaacatac
    79321 ttatgatgaa aataatccaa aacaagctat gaatatatac attgcagtaa ctattcctgg
    79381 taagaaacat tttaatcatg ttcattatgg tcaagagcag atgatatata ttttagaggg
    79441 agagggtttg tatattataa atggagtttg gaagccattt tatcaaggta tgatttttta
    79501 tatagaatct ggtagcacac atgaaactat aaatacaggt gatagagaaa taaaagaact
    79561 tattgtttca aataatgtag atgatgtagg agagagtgaa gttatagata ttaatcctaa
    79621 taattattta aagaagacct tgataaatta tagtgaaagt acattaaatt tgtatgcagc
    79681 agtagaatca attcgtggtc aatttataga cccgtttaaa attccattaa ttatatatga
    79741 tgattcatgg aatatagttt taaaaaatcc ttattttcca cttttttgtt ttgaaaaatg
    79801 taatcctatg aaatttcctc aaaattgtga ttgtatgaat caaaaaagta gcaatcaatt
    79861 tgtatgtgaa tatgggataa ctatatataa tataccaata ctgtacaaaa gtaatagcat
    79921 aggtgttata agaggagggt atgtactatt atctgatttg aatttagata cagagcataa
    79981 taatttatat gatattccag agggagctgc tagaagtata aaacgcctct tgaaacaaat
    80041 atctaaaaat ataataaatt tttgctcttt taatgatata agaaaggatt tacaagaaaa
    80101 agagaagact atagcaagaa catatcatta tggagagcaa cttgaaatga atttaaaagt
    80161 agctcaagat atggttacta atttaagaat aaatcatcac tttttattta atacattaaa
    80221 ttcaatggca agcatagcgc tagatgatgg tagttatgat ttgtatagtg caataataga
    80281 tttatcaaga atgtttagat atacaatgag gtctgattta agatttgtag aattagaatc
    80341 tgaaatatta tacattaaaa attatttgaa tttacagaaa ttacgttatg gagatgcact
    80401 taaagtaaaa tatcttattc cagagaagtt atataacctt tctgtgcctt ttaactttat
    80461 tcaacctatt gtagagaatg catttacaca tggatttaga gatattgaca cagtaaagcg
    80521 aattgaaata attgcaagat tagattctca gtatgctatt atagagattc ataataatgg
    80581 aactatctta gatggaaata atatagacaa aataaaggca ggtattcgta gtaataatgg
    80641 tcatggtttg tctttaatat atacaaaatt cacatctgct tatggaaata attttgatat
    80701 ggatataaag tcgagtgata atgaaggaac ttacataatg attaaaattc ctattgaaaa
    80761 ttataaggag tatgtataga acttgtgaaa aattaataag ttttataaat gttaagaaat
    80821 atattagatg tttttatgtt gttttatata tcttactttt ttatattatt aagctaaaag
    80881 ggaggtattc tcatgagaag agcactaata atagatgatg aagaagctgt tctaaaaata
    80941 ataacacatt ttatagaaat gaaagatatg ccaataaaaa ttgttggtaa agcaacatct
    81001 ggtgatgaag cagtagataa aatca
//
LOCUS       DAGQVA010000007        80173 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.007, whole genome shotgun sequence.
ACCESSION   DAGQVA010000007 DAGQVA010000000
VERSION     DAGQVA010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 80173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.007"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(121..894)
                     /locus_tag="MIV85_000587"
     CDS             complement(121..894)
                     /locus_tag="MIV85_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBY2959963.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="MIV85_000588"
     CDS             complement(894..1280)
                     /locus_tag="MIV85_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2959964.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="MIV85_000589"
     CDS             complement(1305..1622)
                     /locus_tag="MIV85_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBY2959965.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="MIV85_000590"
     CDS             complement(1634..1894)
                     /locus_tag="MIV85_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBY2959966.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="MIV85_000591"
     CDS             complement(1894..2190)
                     /locus_tag="MIV85_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBY2959967.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="MIV85_000592"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="MIV85_000592"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBY2959968.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="MIV85_000593"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="MIV85_000593"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBY2959969.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKRYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="MIV85_000594"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="MIV85_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBY2959970.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="MIV85_000595"
     CDS             complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="MIV85_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBY2959971.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8082..9188)
                     /locus_tag="MIV85_000596"
     CDS             complement(8082..9188)
                     /locus_tag="MIV85_000596"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBY2959972.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="MIV85_000597"
     CDS             complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="MIV85_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBY2959973.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11408..11545
                     /gene="rpmH"
                     /locus_tag="MIV85_000598"
     CDS             11408..11545
                     /gene="rpmH"
                     /locus_tag="MIV85_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBY2959974.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11623..11967
                     /gene="rnpA"
                     /locus_tag="MIV85_000599"
     CDS             11623..11967
                     /gene="rnpA"
                     /locus_tag="MIV85_000599"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBY2959975.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11999..12250
                     /gene="yidD"
                     /locus_tag="MIV85_000600"
     CDS             11999..12250
                     /gene="yidD"
                     /locus_tag="MIV85_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBY2959976.1"
                     /translation="MNKIIYILKEISKHLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12282..12989
                     /locus_tag="MIV85_000601"
     CDS             12282..12989
                     /locus_tag="MIV85_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBY2959977.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12958..13587
                     /locus_tag="MIV85_000602"
     CDS             12958..13587
                     /locus_tag="MIV85_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBY2959978.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13699..15078
                     /gene="mnmE"
                     /locus_tag="MIV85_000603"
     CDS             13699..15078
                     /gene="mnmE"
                     /locus_tag="MIV85_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBY2959979.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENVIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15176..17068
                     /gene="mnmG"
                     /locus_tag="MIV85_000604"
     CDS             15176..17068
                     /gene="mnmG"
                     /locus_tag="MIV85_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBY2959980.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17061..17780
                     /gene="rsmG"
                     /locus_tag="MIV85_000605"
     CDS             17061..17780
                     /gene="rsmG"
                     /locus_tag="MIV85_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBY2959981.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17943..18728
                     /gene="noc"
                     /locus_tag="MIV85_000606"
     CDS             17943..18728
                     /gene="noc"
                     /locus_tag="MIV85_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBY2959982.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18863..19636
                     /locus_tag="MIV85_000607"
     CDS             18863..19636
                     /locus_tag="MIV85_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBY2959983.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19638..20501
                     /locus_tag="MIV85_000608"
     CDS             19638..20501
                     /locus_tag="MIV85_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBY2959984.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20534..21676
                     /locus_tag="MIV85_000609"
     CDS             20534..21676
                     /locus_tag="MIV85_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBY2959985.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21810..22385)
                     /locus_tag="MIV85_000610"
     CDS             complement(21810..22385)
                     /locus_tag="MIV85_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBY2959986.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22645..23937
                     /locus_tag="MIV85_000611"
     CDS             22645..23937
                     /locus_tag="MIV85_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBY2959987.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24042..24644
                     /gene="yedF"
                     /locus_tag="MIV85_000612"
     CDS             24042..24644
                     /gene="yedF"
                     /locus_tag="MIV85_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBY2959988.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24717..24980
                     /locus_tag="MIV85_000613"
     CDS             24717..24980
                     /locus_tag="MIV85_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBY2959989.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24995..25180
                     /locus_tag="MIV85_000614"
     CDS             24995..25180
                     /locus_tag="MIV85_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBY2959990.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25283..26479
                     /locus_tag="MIV85_000615"
     CDS             25283..26479
                     /locus_tag="MIV85_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBY2959991.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26693..26971
                     /locus_tag="MIV85_000616"
     CDS             26693..26971
                     /locus_tag="MIV85_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBY2959992.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27008..27442
                     /gene="ssb"
                     /locus_tag="MIV85_000617"
     CDS             27008..27442
                     /gene="ssb"
                     /locus_tag="MIV85_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBY2959993.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27461..27688
                     /locus_tag="MIV85_000618"
     CDS             27461..27688
                     /locus_tag="MIV85_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBY2959994.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27831..28151
                     /locus_tag="MIV85_000619"
     CDS             27831..28151
                     /locus_tag="MIV85_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBY2959995.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28159..29115
                     /locus_tag="MIV85_000620"
     CDS             28159..29115
                     /locus_tag="MIV85_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBY2959996.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29126..31120
                     /locus_tag="MIV85_000621"
     CDS             29126..31120
                     /locus_tag="MIV85_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBY2959997.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31121..31570
                     /locus_tag="MIV85_000622"
     CDS             31121..31570
                     /locus_tag="MIV85_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBY2959998.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31589..32917
                     /gene="dnaB"
                     /locus_tag="MIV85_000623"
     CDS             31589..32917
                     /gene="dnaB"
                     /locus_tag="MIV85_000623"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBY2959999.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33122..33430
                     /locus_tag="MIV85_000624"
     CDS             33122..33430
                     /locus_tag="MIV85_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960000.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33512..34801
                     /locus_tag="MIV85_000625"
     CDS             33512..34801
                     /locus_tag="MIV85_000625"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBY2960001.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35127..35202
                     /locus_tag="MIV85_000626"
     tRNA            35127..35202
                     /locus_tag="MIV85_000626"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35160..35162,aa:Lys,seq:ttt)
     gene            35209..35283
                     /locus_tag="MIV85_000627"
     tRNA            35209..35283
                     /locus_tag="MIV85_000627"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35242..35244,aa:Glu,seq:ttc)
     gene            35288..35363
                     /locus_tag="MIV85_000628"
     tRNA            35288..35363
                     /locus_tag="MIV85_000628"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35321..35323,aa:Val,seq:tac)
     gene            35397..35471
                     /locus_tag="MIV85_000629"
     tRNA            35397..35471
                     /locus_tag="MIV85_000629"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35429..35431,aa:Thr,seq:tgt)
     gene            complement(35854..36846)
                     /locus_tag="MIV85_000630"
     CDS             complement(35854..36846)
                     /locus_tag="MIV85_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2960002.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36855..37913)
                     /locus_tag="MIV85_000631"
     CDS             complement(36855..37913)
                     /locus_tag="MIV85_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBY2960003.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38038..39501
                     /locus_tag="MIV85_000632"
     CDS             38038..39501
                     /locus_tag="MIV85_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBY2960004.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39603..40400
                     /locus_tag="MIV85_000633"
     CDS             39603..40400
                     /locus_tag="MIV85_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2960005.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40413..42515
                     /locus_tag="MIV85_000634"
     CDS             40413..42515
                     /locus_tag="MIV85_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBY2960006.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42583..43062
                     /gene="rlmH"
                     /locus_tag="MIV85_000635"
     CDS             42583..43062
                     /gene="rlmH"
                     /locus_tag="MIV85_000635"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBY2960007.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43211..43522
                     /locus_tag="MIV85_000636"
     CDS             43211..43522
                     /locus_tag="MIV85_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2960008.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43570..43887
                     /locus_tag="MIV85_000637"
     CDS             43570..43887
                     /locus_tag="MIV85_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBY2960009.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44100..44801
                     /locus_tag="MIV85_000638"
     CDS             44100..44801
                     /locus_tag="MIV85_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2960010.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            45025..46326
                     /locus_tag="MIV85_000639"
     CDS             45025..46326
                     /locus_tag="MIV85_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2960011.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46463..47557
                     /locus_tag="MIV85_000640"
     CDS             46463..47557
                     /locus_tag="MIV85_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBY2960012.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            47559..48692
                     /locus_tag="MIV85_000641"
     CDS             47559..48692
                     /locus_tag="MIV85_000641"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBY2960013.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            48710..49819
                     /locus_tag="MIV85_000642"
     CDS             48710..49819
                     /locus_tag="MIV85_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBY2960014.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            49884..50624
                     /locus_tag="MIV85_000643"
     CDS             49884..50624
                     /locus_tag="MIV85_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBY2960015.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGYVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            50629..51621
                     /locus_tag="MIV85_000644"
     CDS             50629..51621
                     /locus_tag="MIV85_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBY2960016.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVLICGIAMQLTDSIKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51809..52690)
                     /locus_tag="MIV85_000645"
     CDS             complement(51809..52690)
                     /locus_tag="MIV85_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2960017.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52963..54351
                     /locus_tag="MIV85_000646"
     CDS             52963..54351
                     /locus_tag="MIV85_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960018.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54379..55332
                     /locus_tag="MIV85_000647"
     CDS             54379..55332
                     /locus_tag="MIV85_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBY2960019.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIETLTKEKQAGVSLG"
     gene            55392..55616
                     /locus_tag="MIV85_000648"
     CDS             55392..55616
                     /locus_tag="MIV85_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960020.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            55609..56121
                     /locus_tag="MIV85_000649"
     CDS             55609..56121
                     /locus_tag="MIV85_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBY2960021.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQEDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            56153..57007
                     /locus_tag="MIV85_000650"
     CDS             56153..57007
                     /locus_tag="MIV85_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBY2960022.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57541..58335
                     /locus_tag="MIV85_000651"
     CDS             57541..58335
                     /locus_tag="MIV85_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2960023.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            58439..59245
                     /locus_tag="MIV85_000652"
     CDS             58439..59245
                     /locus_tag="MIV85_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBY2960024.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SITVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     AIHQLFNFLIGIINEDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            59307..59828
                     /locus_tag="MIV85_000653"
     CDS             59307..59828
                     /locus_tag="MIV85_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBY2960025.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            60243..62330
                     /locus_tag="MIV85_000654"
     CDS             60243..62330
                     /locus_tag="MIV85_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2960026.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            62345..62632
                     /locus_tag="MIV85_000655"
     CDS             62345..62632
                     /locus_tag="MIV85_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2960027.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            62659..63930
                     /locus_tag="MIV85_000656"
     CDS             62659..63930
                     /locus_tag="MIV85_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBY2960028.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            63988..64587
                     /locus_tag="MIV85_000657"
     CDS             63988..64587
                     /locus_tag="MIV85_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBY2960029.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            64592..65497
                     /gene="dapA"
                     /locus_tag="MIV85_000658"
     CDS             64592..65497
                     /gene="dapA"
                     /locus_tag="MIV85_000658"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBY2960030.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPSKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            65603..66235
                     /locus_tag="MIV85_000659"
     CDS             65603..66235
                     /locus_tag="MIV85_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBY2960031.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            66713..69220
                     /locus_tag="MIV85_000660"
     CDS             66713..69220
                     /locus_tag="MIV85_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBY2960032.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            69562..71724
                     /locus_tag="MIV85_000661"
     CDS             69562..71724
                     /locus_tag="MIV85_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBY2960033.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNETTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRALNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            71729..72346
                     /locus_tag="MIV85_000662"
     CDS             71729..72346
                     /locus_tag="MIV85_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960034.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNKKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            72535..72879
                     /locus_tag="MIV85_000663"
     CDS             72535..72879
                     /locus_tag="MIV85_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBY2960035.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            73449..74315
                     /locus_tag="MIV85_000664"
     CDS             73449..74315
                     /locus_tag="MIV85_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBY2960036.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRIKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            74428..74832
                     /locus_tag="MIV85_000665"
     CDS             74428..74832
                     /locus_tag="MIV85_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBY2960037.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            74999..75448
                     /locus_tag="MIV85_000666"
     CDS             74999..75448
                     /locus_tag="MIV85_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2960038.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(75604..75981)
                     /locus_tag="MIV85_000667"
     CDS             complement(75604..75981)
                     /locus_tag="MIV85_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBY2960039.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            76243..77160
                     /locus_tag="MIV85_000668"
     CDS             76243..77160
                     /locus_tag="MIV85_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBY2960040.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            77644..79062
                     /locus_tag="MIV85_000669"
     CDS             77644..79062
                     /locus_tag="MIV85_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBY2960041.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            79138..79950
                     /locus_tag="MIV85_000670"
     CDS             79138..79950
                     /locus_tag="MIV85_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2960042.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
BASE COUNT        30682 a         9425 c        13359 g        26707 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ctttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa atacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttaacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctatagcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcat gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tatattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat ctctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 acaatacttt tattttagtt ccttctattt caactatatc tcctgatttt atcttttttc
     7801 ctcttcttaa ttctatttca tcatttactg tcactaaacc ttcttgaatt aaaaattttg
     7861 catgacctcc tgttgatgca atctctgcta atttaagaaa ttgatccaac tttatatatt
     7921 ctgattctat agttatttca gtcataatag ttcctccttg tcactatttt aaacaaattc
     7981 ctattgatac actaaaagta tattatacca taaatatgct tataaaagga gttgtctaag
     8041 attagaaaaa ttttctacaa aagacaactc cttcatgtct gctatatatt tgatgatatt
     8101 cttactggaa gcagtaagta aatataatta acatcatctg ttggtttaat tatacaagga
     8161 tttacatttg tagtaaattc tataaatatt tcctcattat ctatattttt caaaccttcg
     8221 ataaaatatc tagaattgaa agctatatct aggtaatctc catctaaatc tatttcaact
     8281 tcttcataca catttccttt ttctgtatta gaagtaattg ccattacttt atctcttata
     8341 gataacttta taagattatt tttttctgat tgagacaata aagacgctct ctctatacta
     8401 tttaaaagtt ccttagtatt taatttaact ctgctgttat gttctcttgg caataatttt
     8461 ttataatcaa taaaatctcc ttcaagcaat cttgtaataa ttttcgtatc attaattata
     8521 aaaatagcat ttttttcgtt aaatccaact ttaacattat cctctccaga aagcaaacta
     8581 tttacatcta taagtgtctt tccaggaatt atgactttta tattttcagt taaactatca
     8641 accgaacaac tttttacagc taatctatat ccatcaattg ctactaaatt taagtttcta
     8701 tctacaattt ctaaaagttc tcccattaaa acaggttttg tttggtcctg tgagatagca
     8761 aatacagttt gtttaatcat attttttagg atttcttgag gtatgctata taaatcttct
     8821 tcatttaatt ctggtaattt aggaaattct tttgctgcat aacctttaat tttaaatctt
     8881 gaatttacac aatttatgta aatattattt tctgaatcag tttctatctc aacaaaggaa
     8941 tctggtaatt ttctaattat atctccaaat agccttgcat ctacaacaac atcacctttt
     9001 tctatgattt ctgcttgtac ataagtttct attcctattt cagcatcata tccagtaagt
     9061 tttaattgac cttcttctgt agatataagt atacctttta ataattctat tgttgttttt
     9121 ccattaatag ctttttgagc aattccaatt ctatttgcta ggattttttg attacaaatt
     9181 attttcaatg tggataacct cctctggctt tttatatata aaaataagtt aaaatcatag
     9241 tagtaatagt agtaggtgtt gttgataatg ttaataagta tgtataacat tataaataca
     9301 aagatattaa catgtgtata agatgttaat atctttgtta ttttagactt gataatttgt
     9361 taataatttt tgttcaaaaa aagtattaac aggttattca agagatataa acatacaatt
     9421 gtgtataaat tatcccttca aatctgatat aattttgtct attttagtct taatttcttc
     9481 actttcttct atatccttag atactttgtc atgagcatga attactgttg tatggtctct
     9541 acccccaaac tcttcaccta ttttaggaag ggataaatca gtaagctcgc gcgttaaata
     9601 catagctatc tgtcttggat aagctattga acgtgttctt tttttagaat taaaatcttc
     9661 catctttaaa ttgaatacag aagatacttt ttcttttatt ctgagaacat ttatttcttc
     9721 atttttagaa gttgttataa tatcttttaa agcttctgta gcaagatcaa aagatattac
     9781 cctattgcta agagaagaat aagcaaccac tctagttaat gcaccttcta gttcccttat
     9841 gtttgactta atattttttg ctatatatga cataacctca tttggcacat ctatacgttc
     9901 tagttgagcc ttttttctaa gtatagcaat tcttgtctca aagtcaggtg cttgaatatc
     9961 agttataagt cccatttcaa atctcgatct tagcctatct tctagtgtag gtatgtcttt
    10021 tggcggtcta tcactagata taattatttg tttgtttgct tcatgaagag tattgaatgt
    10081 atggaaaaac tcttcttgag ttctttcttt tcctgctata aattgaatat cgtcgattag
    10141 taatacatct acgtttctat atttattcct aaattcttcg tttttatcgt cttttataga
    10201 gtttataagt tcattagtaa atttttctga agaaacgtaa actacttttg agtctttttt
    10261 ttgactaaca atatgatgac ctatagcatg cattaggtga gtcttaccta atccaactcc
    10321 tccatacaaa aaaagtgggt tataagcttt agctggagat tctgcaactg caacgcatgc
    10381 agcatgtgca aatctattac tattaccaat aacgaatgta tcaaatgtgt attttggatt
    10441 tagattgggg taaagaactc tataatttaa atctgtgcta tcagaattta aatcagcaac
    10501 ctctttttcg ctcaatacaa atttaatatt atattttttt aatgacagtt gactaatagc
    10561 atcttcaatt aaatgtaaat atctattctc taagatatct ttattaaaat cactaggagc
    10621 cagtaagatt aaatcattaa gatgtatttt taatggtacg atgtttttaa aaaaggtatt
    10681 aaaacttact gaagttaagt caccttttat taattgtagg gttttgtccc ataaagaaac
    10741 tatatccata atataaacct ccgaacagaa taattaatat tttccacaaa gttattaaca
    10801 gaaaagcaaa aatatatata aattttacag aataactaaa tttatggata atggtgttga
    10861 taaattaata atagtataaa ttattaaaaa aatatgaaaa gatataaaca atatgtagat
    10921 aaagttataa ataacataaa catacaataa atggtgatta taactagagt attgtcagta
    10981 atcttaaaag ttatacacaa aagtatccac aagctgtgaa taatttctaa taagttgata
    11041 acatttatgc acattatcaa caagtatatt tataatatca aaatatatgt caaacttcaa
    11101 tgatttgtaa ctaatttatc cacaatatta actaattgtt gataaaaata taaacatgtt
    11161 aaaattactt tatttgtgta tataattgaa aaaaataatt tagaataaaa ttaaatagat
    11221 ttttactagt attttcaata aaaaaaatac ataatatata tatggtagat tttgtgatat
    11281 aagcgtccca aaaactcgtt gacaacagta gtaaaagtat ttataattat atgtgttatg
    11341 tttactttga gggtaaagtt attattttta taaacggaaa ataaaatctg aaaggcggtg
    11401 caaaataatg agtaaaagaa cttatcaacc aaaaaagaga caaagaagta aagaacatgg
    11461 tttcagaaaa agaatgaaga cgtctaacgg aagaaacgtg ttaaagagaa gaagagctaa
    11521 aggaagaaat agattaactc attaattaca aaagggccgc tgcaaaggtg gcctttttgt
    11581 gtaaataatt acaattcata gctgtgttta tggaggttaa ctatggactt taataggact
    11641 aaagggttga aaaaagactc tgattttaga aaagtatata aacacggcaa atcttttgca
    11701 aacaaatatt tagtaatata tatacttaaa aataaatcag attatagtag agtaggtatt
    11761 tctgtttcaa aaaaagtagg aaaagctatt actaggaata gagtaagaag attaataaaa
    11821 gaagcctaca gattaaatat tgatgaaaaa attaagcctg gatatgatat agtatttata
    11881 gcaagggtat ctagtaagga tgctactttt aaagacatag acaagtctat aaaaaattta
    11941 gttaaaagaa cggatatttc tatttaattg tatgctataa atatggaggt taatgacttt
    12001 gaataaaata atttatatat taaaggaaat aagtaagcat ttatcgaatt tatgtattta
    12061 tttagtgaga ttttatcaaa agtatatatc tcccttaaag ggacctacct gtagatttta
    12121 tccaacttgc tcacaatatt caatagaggc gtttaagaaa tatggatttg taaaaggtat
    12181 gtatttaacg ataagaagac ttttaaaatg tcatcctttt catccaggag gttacgaccc
    12241 tctaaaataa aagagagtaa ctattaggag gtataaaaaa attgaatata ataggaaatt
    12301 tcttaggatt gattcttaag gtaatatttg aatttgttaa tcattatggt atttctataa
    12361 tactttttac gatacttgta aagattattt tattaccatt aacaattaag cagactaagt
    12421 caacaaaggc aatgcaagat atacaacctc gtataaaaga gatacaagaa aaatataaaa
    12481 ataagccaga aaaacaaaat gaagaaattg ttaagttata tggagaagct aaaattaatc
    12541 cactatctgg ttgtttacct ttattaatac agtttcctat attaatagga ttatttagcg
    12601 ttttgagaga accagttgct catggcgttt ttgcaaacaa agctgcattt ttagcagctg
    12661 acaatgggtt tttatggata aaaagcttaa catcaccaga ttatgtatta gcagtatttt
    12721 caggagcaag tgcatatgtc atgcaaaaag taatgacacc aaaagatcag ttacaaggct
    12781 ctatgaaagt aatgacatat gtaatggcag gtatgtcttt ctattgggga tttatattcc
    12841 cagcaggact tacattgtac tggacagtaa gtaacttatt ctcaatagct caatattact
    12901 taataatgaa tcctttaaaa gctaaactgg ctgctaactc taaggaggaa aaagttaatg
    12961 agaaaaagcc taaaattaat aaaaagtaag agtaaagagg aagctataag taaagctata
    13021 gcagagttga atttaaaagc agaggatata gaagtagaaa tacttgaaaa tccaagtaaa
    13081 gggtttttag gttttatagg tgctaaagat ggtacttatg aaatttttgt tatcgagagg
    13141 gaagtagatg tagctaaaaa ttttatagag gtaatgttga aaaatgcaaa tgttgatgcc
    13201 aaagtcaatg tatctcaaaa agataattta atcatggttg atattgaagg caaagaagct
    13261 gcaagtttaa ttggtagaag aggggaaact ttagattcta ttcaattttt gactggatta
    13321 gctcttaata aaataaataa agattctcat acaagagtac ttgtagatat agaaaattat
    13381 agatcaaaac gagaagaatc tttaataaga tatgctaata aagttgctag agaagtagcg
    13441 aaaacaagaa aaactaaaaa attagattat atgaatccat atgagagaag aataatacat
    13501 tcagctcttc aaaatgacaa atatgtaatt acatatagtg aaggaaccga tccatataga
    13561 agattagtaa ttgagtgtaa aagataaagt caacctccta aacattaggg ggttttattt
    13621 tttaatatta ttaaatcatt aatggttggt taaatgtaaa tctatatgta aaaaattatg
    13681 aattaagagg tgataaattt gtttatagat gatacaattg cagcaatagc tacagcacct
    13741 ggagaaggtg gtataggtat acttagaata agtggagaaa aagctttgaa ggttgcagaa
    13801 gaaatcttta aatctatgtc tggaaagagt attgaagaat acaataagag aacattaata
    13861 tatggaaata tagtggataa tgaaaatgta attgatgaag ttttattggc atatatgaaa
    13921 ggaccaaatt cctatacagg agaagatgtt atagaaatta attgccatgg tggatttatt
    13981 tcggtaaaga agatattaga attaatacta tcaaaagatg ttagattagc agaggctggt
    14041 gagtttacta aaagagcatt cttaaatgga agaatagatt tatctcaagc agaggctgta
    14101 attgatgtta taaaagccaa aactgatata gctcatgaag ttgctcaaaa tcaattagag
    14161 ggttctttat caaagaagat aagagaattg agagataaag tcactgagat attagctcat
    14221 gtagaagttg ctatagatta tcctgaggaa gatattgagc atataacata tcaaactctt
    14281 aaagaaaaaa ctgatgaact taaaaaagac attaaaaaat tatatgatac agctgaaagt
    14341 ggaaaaatac ttagagaagg cttaaagacg gtaattgttg ggaaaccaaa tgtaggtaaa
    14401 tcttcactac ttaattctat tttaggagag aatagagcaa tagttactga tataccagga
    14461 actactagag atgttataga agagtttgta aacataaaag gtataccttt aaaaattgtt
    14521 gacacagcag gtataagaga tactgatgat attgttgaaa aaataggtgt tgaaaagtct
    14581 aaagaatcat ttactagtgc agatttgata gtaatggttt tagatgcatc tagaaagttg
    14641 tcagaagaag atatagagat attagaaaaa cttaaggata aacaaacaat agtgctgtta
    14701 aataagaatg atttgaaaca agagattgaa gaagaaaaaa tacttaaata tgtagaaaat
    14761 aatagtataa taaaaatatc agctttacaa caagaaggaa tagaagaatt gcaagataaa
    14821 atagagtcta tggtatataa aggtagtatc aaaaataatt ctagtttagt agtaacaaat
    14881 tcaagacata aagatgcact tagtaaagca tataaatctg caacagatgc tttaattgct
    14941 ttggaacaaa gtatgccatt tgactttgta gaagtcgatt taaaaaatat atgggactat
    15001 cttggatata ttaatggtga tacagtaaca gaggatttac tagataatat attccataat
    15061 ttctgtattg gtaagtaatg tacaaaagta aacttgtttt tattatagag atttttaaaa
    15121 aatttgaagt gtttctcatg aaacattaat tttgaaaaga aaggaattat aaatgataaa
    15181 gtttgaagca ggaaaatatg atgttatagt agtcggagca ggacatgctg gatgtgaagc
    15241 tgctttggct actgcaagaa tgggatataa aactttgata ataacaatgt ctttggattc
    15301 catagcatta atgccttgta atccatcaat tggagggact ggtaaaggtc aattagttaa
    15361 agaaatagat gccttaggcg gtcagatggg attaaatata gacaagacat atatacaaag
    15421 tagaatgtta aatactgcca aaggtccagc ggtacactct ttaagagcac aagcagataa
    15481 atttaaatat catgaagaaa tgaaaaagac attagaagat gaaccaaatc ttgatatagc
    15541 tatggatgaa gttgtagaaa tacttcatga aggaaatgtt gtaataggag ttggaactaa
    15601 actaggatgt tcatttaaat ctaaagctgt aatattggcc actggagttt atctgaactc
    15661 aaagatatat atgggtgaag ttgcatttta tgaaggtcct aatgcattag ggtatgcaaa
    15721 atatcttaca gatagcttag ttgagcttgg ccttagaatg agaagattta agacgggaac
    15781 tccagcaaga gttcatagag atagtataga cttctctgta atgtctttac aagagggtga
    15841 tgaaaaagta actccattct catttatgaa tgaaaatata gaaaaaaaac aagaaccttg
    15901 ttatttaaca agaactacag aagaaactca aaaagttata ctggataatt taaaaaggtc
    15961 tgctatgtat agtggagtaa tagaaagtac tggtccaaga tactgtcctt ctatagaaga
    16021 taaagtagta agatttagtg ataaaacatc acatcaatta tttatagaac cagaagggtt
    16081 aaatactaaa gaaatgtata tacaaggaat ttcaactagt ttaccttttg aagttcaatt
    16141 agatatgtac aaaactataa aaggacttga aaattgtaag ataatgagac ctgcatatgc
    16201 tattgaatat gattgtgttg acccaactca actaaaaata agtttggaaa taaagggtgt
    16261 tgagaactta tttagtgcag ggcaatttaa tggaacttct ggatacgagg aagcagcagc
    16321 tcaagggctt atggctggta taaatgcagt tagaaagata gaaggaaaag agccatttgt
    16381 attagaccgt tcagaagctt atataggtgt cttattagat gaccttgtta ctaaaggaac
    16441 taacgagcct tacagaatga tgacatcaag agcagaatat cgactatatt taagacaaga
    16501 taatgcagat atgagattaa ctcaaaaagg ttatgatata ggattagtta aaaaagatag
    16561 atatgaaagg ttcctaaata aaaaggctgc tgtagagaaa gaatttgaaa gactaaaaaa
    16621 tgaaagagtt acaccaaaag aagtaaatag tttgttggaa gaaaaaggag caacaccaat
    16681 aaaggttgga atatctctat atgaattttt aaagagacca gaggttactt acgaattgct
    16741 tgaagaatta gggaaaggcg ctggagaaga tgtttcaaga gaagttaaag aacagtgtgt
    16801 aataataact aaatatgaag gttatataga gaaacaattg aaacaaatag accaatttaa
    16861 aaaacttgag aataaaaagt tggatgagaa aataaattat tcatctatag aaggtcttag
    16921 attagaagct agacagaaat tagatgatat aaaacctatt tcaatagggc aagcatctcg
    16981 tatatctggt gtttctccag ctgatatatc agttttactt atatacctag aacaaatcag
    17041 aagaactaga ggtggcaaag gtgaataata tagaacttct gaaaaacggg attgaaggtt
    17101 ttaatataga tacgaatgac agtatgttag aaaaatttaa aatctataga gagatattag
    17161 ttgaatggaa taaaaagatg aatcttactg gaatagaaga tgaaaaagaa gtgtatataa
    17221 aacatttttt agactctatt tcagctgtaa aaaatggata tataaaaaat gggatgtcta
    17281 taatagatgt tggtacaggt gctggttttc ctggaatacc attgaaaata tgtttagata
    17341 gcttagaact tactttgtta gattcgttaa ataaaagaat aaacttttta gaggaagtta
    17401 gtagagtact agagttagat aatattacat ttatacatgg aagagctgaa gattttggta
    17461 aaaatgaaga ctatagggaa aaatatgatg ttgctacggc aagagctgtt gctggattac
    17521 cgattcttat ggaattttgt gtaccatttg taaaagttgg agggtatttt atttgcttaa
    17581 aaggtccgaa tgctaattta gagctagaag aatcacaaaa ggctattgat gttttaggat
    17641 tggagtatat tgaaaaaata gatgtagagt taccagaggt agatttaaat cataatatat
    17701 tagtttttaa aaaagtgatg gaaacaccag ttaagtaccc tagaaaagct ggtaaaccag
    17761 ccaaaaatcc tattaagtaa tgaaaaattt attattggta agcttaatta tttctcagga
    17821 aataattaag cttactgtaa aaaaacaaaa ataaaggaat tattaaagta gatgcagaaa
    17881 taaatttgta tgtacatata gagaacaaaa ataatttata tctaaaataa gagaggtatg
    17941 ttatggaaga taaaagagtt atggagatac ctatagaaga tgtagttcca aatccatatc
    18001 aaccaagaaa aatattttca caagtttcat tggaggaatt gagcaattct ataaaggtat
    18061 atggtataat tcaacctata acagttagag caaaagatgg caaatatgaa ctaattgcag
    18121 gagaaagaag attaagagca gctaaattag cagagcttaa aaccatacca gcaattataa
    18181 ataatatgaa cgatgaatct tctgctgttc tagcgttatt agaaaatttg caacgagaag
    18241 acttaaattt cattgaagaa gcaattggtt atgaaaactt aataaaagaa catgctttta
    18301 ctcaacagca attagcagaa aaattgggca aaaatcaatc tactgtagca aataagctta
    18361 gaatattaaa gcttccaaac gatataaaaa tgaagctaat agagaataat ttaacagaaa
    18421 gacatgctag agcatttctt aaactaccaa gtgaagattt aatgcaaagt gtgttagaca
    18481 aagtcataaa aaatgaattg actgttaaaa aaacagaaaa attgatacaa gatgtattag
    18541 aagaaactaa agttcaagaa gagcctgata aaaaacagaa tataaagggt gctatgagta
    18601 taagaattta cataaatact ataaagcagg cctttgatgc tatatcaaat acaggaattg
    18661 atgctaagta taatgaaata gataagggag attatatgga agttgttgta aaaatcccta
    18721 aaaaatagag attactgctt accagtaatc tttttttgta atataagcct tgtaatataa
    18781 attgatttat agacattatt tatacttaaa aaacacctat tcaacattta aaattaattt
    18841 aattcttaaa ggggggaaca tcatgggcaa agttatagct gtattcaatc aaaagggtgg
    18901 agtcgggaaa actacaacaa atgtaaattt aagtgctagc ttaggaactt tgggaaagaa
    18961 aatattagta ttagatttag acccacaagg aaatacaact agtggatatg gtattaataa
    19021 aaacgaagta gaaaatacaa tctatgaaat tatgttagat gggttacata ttaaagaagc
    19081 aataataagt actgaatttg agaatgtaga tgtagttcca tcagctactg aactatcagg
    19141 tgcagagata gagcttacat ctaaaactaa tagagagtat attttaaaaa attccataaa
    19201 agcggtaata gatgaatatg attatatatt tttagattgt ccaccctcac tggggatgct
    19261 tacaataaat tgtttaactg ctgtagatag tgttttaatt ccaatacaat gtgaatatta
    19321 tgctttagaa ggtgttagtc aattaatgga gactataaaa ttagtaaaat caagattaaa
    19381 tgctgatata gaaattcaag gtgttgtttt aagtatgttt gatggaagag ctaatttatc
    19441 aatacaagta gttgaagaag ttaagaaata ctttaaaggt agtgtatata caactttaat
    19501 tccaagaaat gtaagacttg cagaagctcc aagtcatgga aaacctgtaa tttattatga
    19561 taaaagatgt agagggtctg tagcttattt ggaactagca gaagaattta tagatttaga
    19621 agaggaggaa tggtagtatg gagaataagt ctaaaagaag taatagatta ggtagaggtc
    19681 ttagtgcatt gataccagaa attaaaggag aaacttcaga aaaagaaata gtcaacatag
    19741 atatagacaa aatatatcca aacgaagttc aacctagaaa gcaatttgat gaagaaaaga
    19801 taaaagtatt gtcggattct ataaaaaatt atggtgtttt acagccaata gtggttaaaa
    19861 tggatgaaaa taataaatat atgataatag ctggagaaag aagatttaga gcatcaaaac
    19921 ttgcaaataa aaatcaaata cctgctataa ttaaagatat agatatgaaa gatataatgg
    19981 agatagcctt aattgaaaac ttacagaggg aagatttaaa ttcaatagaa gaggctctag
    20041 catataagag tttaatagag cattacaatg taactcagga agaaatatca gaagctgttg
    20101 ggaagagtag acctcatata actaatacac taagactttt aaatcttgga caagatgtta
    20161 tagaaatgat agacagtggt agaattacag caggccatgg taaggcttta ttgagaattg
    20221 cagataaaga tttgcaactt caaatagcga aaaaaataga agaagaagaa ctttctgtaa
    20281 gagaagtcga aaatatagct aaaaaaatat ctgaaaataa acaagaagaa cctaaaaaat
    20341 ctaaacctaa ggatgtattt attttagatg ttgaagataa acttagaaat atatttggaa
    20401 caaaggtgaa tatttctaaa ggaaagaaaa aaggtaaaat agagatagaa tactataatg
    20461 atgatgattt aaatagtatt gtatcaatgc ttcttgaata gaacaaaaat ataaaacaga
    20521 gaggaagatt gttatgattt atttagataa tgctgcaact acatatccaa aaccagaaag
    20581 agtgtataat gctgttttag attgtatgaa aaattattgt gcaaatccag gtagagcagg
    20641 ccataaactt gctatgagag ctgctaggga gatatatgat acaagagaga atatagctaa
    20701 gttgttcaat gtaagtaatc ctatgaatat agtatttaca tctaatgcaa cagattcttt
    20761 aaatttagcg ataaaaggtg tattacaaga aggagaccat gtaataacaa cgtctatgga
    20821 gcataattca gtaataagac ctataaaagc attggaaaaa aggggtattg aaaatactgt
    20881 agtaaaatgc gattatgagg gatttttaga ttatgaagat ttagaaaaat caataaagaa
    20941 taatactaaa ttgattgtaa caacacatgc gtctaatgta tgtggaactt taatagatat
    21001 aaaaaaagtt ggagaaatag ctaaaaaaca taatatacta tttttagtag atgcatcaca
    21061 aacagcaggt gtttatgata tagacgtaaa tgaatgtaat atagatatgt tggcaatgcc
    21121 aggtcataaa tgcttatttg gacctcaagg aacaggtata ttatatgtaa gagaagggtt
    21181 gaacttaaat atattaaaag aaggtggaac aggtagtaaa tcagaagaaa tagttcaacc
    21241 agagttattc ccagataaat atgaatcagg aactcataat actccaggta tagcaggtct
    21301 taaccaaggt atactattta tatttgaaag aggaatcaac aatataagac aacatgaaga
    21361 agaattatgt caatatatga tagacaaatt agaggaagta ccagatataa agatatatgg
    21421 accaaaggac agtaaaaaaa gagcatcagt aatagctcta aatataggag atatggattc
    21481 tggagaggtt actttcttat tagatagtga ttataatata gcgactagat caggaataca
    21541 ttgttcacca ctagcacata ccactttagg tactttaaaa caaggtgcag taaggttcag
    21601 tataggatat ttcaacacaa aagatgagat agataaagca gtggaagctt tgaaaaaaat
    21661 ttcaaaaaat aaatagcatg agatttaata atatagaaat aaaaaaaggg gatatttcaa
    21721 aataaaaatt tgaatcatct ccttttttgt acaaaaaaga aaaggggttc ctaagaacct
    21781 ctaatctatt tgataatagt ttcaagaaat tactttaagt aatctccttc ttcaagaact
    21841 atatgaccac tttcgtaatt agaaccatca acagtaattt ttatttgttc aacattcata
    21901 ttttttatgt aagtacgagc aactgaatca agcattaaag tttctgcatc actacctaag
    21961 tttgactttg taaagtcaga gctaacatct aatataccag tttttacacc atcaatgtct
    22021 tttgtagtaa atgaatttaa ttttgcagat tctggaacaa ctttaagttt ttgaagttct
    22081 tcaaataaag tgttctcatc aattttattt aaatcaactt tattttcaat taaatctgtc
    22141 ttatctacat caaaagagta aatagtagct gattgagctt tagtttcttc ttttggagta
    22201 ggtttagctt tgttattagg aacctctttt tcagtattgt tttcttcttt tggttgctca
    22261 acatttgtat tgctcttagt ttctttttta gatgaatcac ttccattttg agcattagta
    22321 caaccaactg cgaatataga tatagataat atacttaaca ctaacattat tttcttattt
    22381 ttcataaaaa tttctcctct cttaaaaact attcttatat ataattatag tcgttatgag
    22441 caaatatatg aatacaaaat agtaacaaat ttaaaaaatg atttatttaa attaataaaa
    22501 ctcaaaataa actaaatttt agtcattttt atgggaaatc atttaatgta cagtgaaaat
    22561 attgtaaaat aaaagtagtg tttttaaaat aaatataagt tataattata ttataaaaaa
    22621 atgtcttcaa aaggtgggaa tagtatggaa attttgagct taggagaaaa gattaaaaag
    22681 ttaagaaaag aaaaaaacat gacattgaaa gaattagctg gagataggat aacagcagca
    22741 caaataagcc atatagagag agataaatct catactagtt atgaactgtt ggaatatcta
    22801 ggcgataagc tagatgtaag tgtagaatac ttattagaga ccaaggaaat gcaatcaaaa
    22861 aagataactg ataatttaat actacagagc gaaatttata taaaagaaaa tgaattaaac
    22921 aaggctgagg accaaataaa agaagtttta gatatatgta agagatacga tttaatggag
    22981 aactatggca gatgtaattt tttaatggct aatattaatt tgaaaaaatc taattataat
    23041 gatgctatag aaaactttga aaaggcattg tacttcttta taaaaaatag tgatagtgaa
    23101 aatatactta agtgttattt aaacataggg aaaatatata tgcaggaaga cttttataaa
    23161 ggtgctataa gccactttaa ttttgcagag gaaattttgt cagagagtaa atttgaggat
    23221 gttaacatac acaaggaact atatagtaag atggcatatt gttacataaa actagataat
    23281 ccaaatatgt cattgaagta catagaaaag ataaatgaaa tagataatag aaatgataga
    23341 aaagaagatg tcgatatttt ggtgttaaaa gcaaataata tgcttgagat tggaaaatat
    23401 gaagaatcaa gagattactt taaaaaagca ctaaaaatac ttgagagtga ggataataaa
    23461 actggattag caaatgtgta tttaacaatt tgtgatgttt acagaaaaat aggtgaaaca
    23521 gatagagtac ttgaatattc acaaaaggta tatgacataa agaaaaatga tgaagatgaa
    23581 tacatgatgt caggattatt taagataata gaagcatata tagataaaga agattatgat
    23641 ttagctagaa aatattgtaa gatagcctta gcttcatcaa taaaaaataa aaataaattc
    23701 aatgaatata aagcattgag attctatgct aatatgtata aaaatcagaa tgaagtaact
    23761 cttgcaattg aatatctgat taaatgcata aaaatagtat cagatttagg caacaataga
    23821 atattggcca atttatatat agacttaggt caattatatt caaatatatc aaaagaaaaa
    23881 gagttagaat attatcaaaa aggtgtattt atgtacaaaa atttagaaat aatgtagggt
    23941 aaataaacct ataagggtat agaaacaatc tataacaagc aagataatat ctatgataaa
    24001 atataaattg tatgaatatt tttaaggaga tgaatcagac aatgagtata aaaatagatg
    24061 cgagagggct tgcttgtcct aaaccagtta taaatacaaa aagagaattg gataacctag
    24121 aagaaggtgt tgtagttaca atagttgata atgaaacagc taaggagaat atattaaaac
    24181 ttgctaaatc tttaagttgt gaagcaaata ttgttgacga aaaagagaat tttatatcta
    24241 tagaaattag aaaaggtaaa aatatactag ataaacaaaa tgttgtagat aataaagaaa
    24301 gtgaattaga caatacatgt atatttatat cttcagataa gatgggactt ggaaatgacg
    24361 aattaggaaa agtgttaata aaaggattta tatatacatt aacagaatct aaaccttatc
    24421 ctaagtatgt acttttagtt aatggaggag taaaattaag tgctgaaaat gaagaaacca
    24481 tagaaaatct aaaaatactt gagaatatgg gtgtagaagt tttatcttgt ggtacttgtt
    24541 tagattatta taatttaaaa gacaaattac aagtaggtac agttacaaat atgtatacta
    24601 tagttgagac attaaagaat gcatcaaata ccatttctat ataatgtatg tatgtttaat
    24661 aatataaaac taacaataaa gattaactca aatagatagt cagaaaggat taagtaatga
    24721 atcaaatgta tatagtgtca tttaattcga cacatcatgc gataagatca gaaaagttat
    24781 ttggtgaaaa tagtctaaaa gtaatggctc ttccaacacc aagagaaata acagcaagtt
    24841 gtggaatatc aattaaattt tcttttgaag atatggaaaa gataaaaact attttggttg
    24901 aaaataatgt agatataaaa ggaatttatt gtataagtaa attagaaaat ggttcaaaag
    24961 aagtagagaa gttagattag gaggctaatt atttatgcca atggatttaa aaataggtga
    25021 tattgttgaa ttaaaaaagc aacatgcatg tgggtgtaaa gagtttgaaa tcataagaac
    25081 gggaatggat ataaagataa aatgtactaa atgttcaagg ctaataatgc ttgatagaga
    25141 gaccttagaa aagagagtaa aaaagctaat aaaaaagtga taaaaattta acacttaaaa
    25201 aatgtcaaat accgtatatt aatatccaaa attttggtat aataagaatt gaagaaaaca
    25261 ttttcatggg ggtgctttaa ttatggcagt taaatatgca aaaagaatgc aaggattaca
    25321 aggatcagaa atacgtgagc ttttaaaact tactcaacaa ccacaaataa tatcttttgc
    25381 tggtggaatg ccggctccag agttatttcc agttgaggaa atgaaaaaag tatcagttgc
    25441 agtgcttgaa gaaaatggaa gatcagctat gcaatatact acaacagaag gatatgaacc
    25501 attaagagaa aaaatagcag ctagaatgaa tgataaaaac aaaactaatg taaacaaaga
    25561 tgatatatta gttacaagtg gttctcaaca aggtctagat tttgcaggaa aagtatttat
    25621 tgatgagggt gatgtaattt tatgtgaaag tccatcttac ataggagcta taaacgcatt
    25681 taaatcttat caacctaaat tcatagatgt tccaacagat tctgatggaa tgataatgga
    25741 agaattagaa aagatactag aaacaactga tagaataaaa atgatttatg taatacctga
    25801 cttccaaaat ccaacaggaa gaacttggcc acttgaaaga cgtaaaaaat tcatggaaat
    25861 agtaaataaa tttgaaatac cagtaataga agataatcca tatggagatt taagatttga
    25921 aggagagact ttaccatctt taaaatcaat ggatacaaaa ggattagtaa tattcttagg
    25981 aactttctct aaaatattct gcccaggata cagattagga tggacttgtg cttctccaga
    26041 aattttatct aagtttaact ttgcaaaaca aggtgcagac ttacaagcat caactatatc
    26101 tcaaatggaa gtaagcaaat ttatggatat gtatgaccta gatgcacatg ttgacaaaat
    26161 aaaagcagtt tatgttaaac gtagagatgt aatgcttaag actatggaag aagagttccc
    26221 agaaggatta gtatttactc atccagaagg tggattattt acatgggtag agcttccaag
    26281 taatttaaat gctaaagaat taatgccaaa atgtttagat aagaatgttg cttatgttgc
    26341 tggaggagga ttcttcccta atggtggtag agaaaatact ttcagactta actattcaaa
    26401 tatgccagaa gaaaaaataa tagaaggtat aaaaaatata gcagctgtat taaaagaagc
    26461 tatgggtgta gaagcttaat taaaaataat aacttatata taatacaagg gatggttgtt
    26521 gccatccctt gtttgtttga aaagtatata attcacctta tactaaactt tgtccaaaat
    26581 ttaaattgac agaaataaga ataaatgata aaatgtgtag gtatgagatt ttagtctcat
    26641 ttctctgctc taagagtgta gagccgttaa gtccaaaggg aggtgaatta tagtgagaaa
    26701 ttatgaatta gtttatgtgg taaagccaaa ctctgatgaa gaagtaagag aggctatact
    26761 aaacaaagtt aaggaagttg ttgcaactga cggagaaata gttaaagttg atacttgggg
    26821 aactaaaaaa ttagcttatc caatagctaa gtttacagaa ggtttctatg tattagttaa
    26881 cttcaaatca gcagtagacg ttcctaaaga gatagacaga aacttaaaga taaatgaaaa
    26941 cgtaataaga cacatgatag ttgttgctta ataactggtt ttattataaa aaataggtgg
    27001 tgtttttatg aatcaagttg tattagtggg aaggttgact agagaccctg aattaagata
    27061 catcccaggt acaggaacac cagtggcatc ctttacaata gccattgata gagactatgt
    27121 aaaaaaagat ggatctaaag aaactgattt tatacctgtt gaagtaatgg gtaaatctgc
    27181 tgaattttgt gctaactaca taactaaagg tagattagta gcacttcaag gatctataag
    27241 agtagacaat tatcagacac aatcaggtga aaagagaact tttacaaaag taagtactag
    27301 atcagtacaa gctttggata gtaagaataa atcggaaaat tcatatagag agagtgctcc
    27361 agcttttgag ccaagctttg aacctcaagg tttagaccca caaggtttcc aagctataga
    27421 tgatgacgat ataccatttt aaaaaggagg gaaaaaagtc atgatgaata aaaaaagacg
    27481 taagaaaaaa agagtttgtc aattttgtgc tgacaaaaac gctaaaatag attacaaaag
    27541 tactcaaaga ttacaaaagt atataactga aagaggaaag atattaccaa gaagaatatc
    27601 tggaacttgt gctaagcatc aaagagaatt aacagttgct ataaaaagag cgagaaatat
    27661 agcactttta ccatatacat tagactaaaa aaatgagcct tgtgctcatt ttttattata
    27721 tgtatttata tatctaaatg aggcgagcta taaagctcgt ttttttgttt atatacttaa
    27781 atatattatt atttatgata taatattata tattaaggag ggttgtaaac gtgaaaatag
    27841 ataaaggttc tgagataacg agaaacataa agataataga atggatgaaa acagaaatat
    27901 taatgagtgt aagtgatttg tttaatttat tgtttaaagg ggtaaaacca ttagatgaag
    27961 caattcaaga tactttagca aatataataa tgataacata tctcttagca aagagattag
    28021 gaattagttt tagagatgtg gattataaag tcaaggaaaa aataaaaatt ggtatagatg
    28081 aggaccatag cgttgaaaga tggtatggag atttatctaa tttaaaaaaa catatggata
    28141 atagggagtg atattaaatt gaataataaa attagactat ctaaggcaat gtctataata
    28201 gttttagcta taataatcgc tttagtaata gcctatattc caatgctagg aatatttagt
    28261 atgttagcag ctgttccata tgtaattata ggtgctatta ctgatagaaa gtattctctt
    28321 atatctattt tggttacatt ttgtgtactg attctatttg cagacatttc ttatgcatta
    28381 aatatatgta taatgtattc tttaccaggt atagtaatag gaaagatgct aaagagaagc
    28441 tttgaacaag aggacagtaa taaattcgaa ccgatatatg gtggaaccat aatatttgta
    28501 ctttcaatgc ttgtatattt ttttgtatta aagacatttt taaatgtgaa tctattagat
    28561 gaagtttcta agatgatatc agaaattgta aatattcaaa aaaatagttt ttctgcaact
    28621 gaacttaaag tgtttgataa aatgaagcca gatgagattg taagttattt tacaaatatg
    28681 ctaccaatga tgttattttt acaagggttg ttatcagcgt ttgtcacata ttatttgagt
    28741 gtatttttta taaaaaggat tacaaagatg aatataagat ttcctaagtt tgctgatttt
    28801 tatttaccgg gaaatgctat actcacaact ttcttacttt atttattagt cttatttatt
    28861 caaattattg gttcaaaatt atatacagaa ttaataatga ctaatttaca gctagttttt
    28921 aatttaatgt ttgtaattca aggtatagca gtttgcattt atttcttaaa gaaatggata
    28981 agacagggac caaataaaat tatgtttttt tcagggataa ttttatgttt atttggattt
    29041 atgggaatat cttttgttgg tatggtagat agtataattg actttagaaa ggtaagaagc
    29101 tataaatcca cttaggagga tagaaatgag taataaacaa acctttaaat taaatatgcc
    29161 agaaataaat ttatatataa ttgttattgg tatttctagt ataattttgc tttattacaa
    29221 cttgtatgta gggtgtttat ttttctgtat ttttgtatat atggtttttc acaattggag
    29281 aactactaat attagacgtc atgaatggac agagtatatt caaaatttat ctttagatat
    29341 agatgaaaca actaaaaaag ccataataaa tcttccaata ccattatgta ttttagaatt
    29401 tgatggaaat atatcctggt ataatggaaa gttttatgat atgattggtc aaaaagattt
    29461 acttgataaa aatatagagg atatagttaa aaatcttaat ttaagaaaag tattaaatga
    29521 aaataaagag atgtacacag aaataaacta taaagaaaaa gaatatacaa taatttataa
    29581 tgttataaaa aatgatcaag aaaaaaatcc taaatatttg atgatattat actggataga
    29641 caagactgaa tatttaaaag taaaacaaaa ttatgatgat gaaaaaaatg caatgatgct
    29701 aatacaagta gatggatatg atgaagtatt aaaaagtgca gcagaagata agagagcttt
    29761 aattaatgtt gaagtagaga aaatactttc tgctttagaa ttaaattcaa atggtgcatt
    29821 gagaagaact tcaaaagaca aattcttctt ggtaatgcat aaaaaagagt taaaaaaatt
    29881 ggaagctgag aagttttcta ttttagatac aataagacat attgattatg gaaataatct
    29941 tcctgttact ataagtatag gaattggtat agatggagat acattaaatg agaacctaaa
    30001 acttgctacg ggtgctctcg atttagcact tggtagaggt ggtgaccagg ctgttgtaaa
    30061 aacaaaagat aaatttgtgt tttatggagg aaaatctaaa gctgtagaaa agaaaaccaa
    30121 agtaaaatcc agattaatag gtcatgcttt aagagaggtt atacaacaaa gtgaccaagt
    30181 ttatataatg ggacataaat atcctgatat ggatgctatg ggagcagcag ttggtgttta
    30241 tgatatatgt aaatcctgta acaaaactgc aaacatagtt ttacaatctg taaatgaatc
    30301 tatagaaata tttataaata aaataaatga aaataattac tataaaaagt tgtttattgg
    30361 aaaagaggaa gctattgaca actgcactaa aaatacatta gttgtagtag ttgatactca
    30421 tagaccaaat tatactgaat gtgaagaact gttaaagcta tcagagaagg tagtagttat
    30481 agaccatcat agaagaggtg tagagtttat aaatgatgca gtgcttttat tccatgagat
    30541 atatgtatcc tcaacgtgtg aaatggttac agagttagtt cagtatatgg atgaagatgt
    30601 aacaataaat aaacttacag ctgaagggct tttagcaggt ataagtctag atactaaaaa
    30661 ctttgcattc aaaacaggtg ttagaacttt tgaagctgct tcttacctta gaaaagttgg
    30721 agcagatact atagaggtaa agaaattctt caattctgat gtaaaagatt tcataataaa
    30781 agctgaaata attcaaagta ctaaaataat taataataga atatgtttag catattcaag
    30841 tactgagata gatagtataa atgttataat agctcaaact gctgatgagt tattaaatat
    30901 caaagaagta gaagcttcct ttgtattagg tgaaaaagat gatactatat ttataagtgc
    30961 gaggtcttta ggacaaataa atgtacatgt acttatggaa aaattaggag gcgggggaca
    31021 catagatata gctggagcac agttaaaaaa tgtttctcta aaagaagctt ataagatggt
    31081 aaataaaata atagaggagt atttggagga ggaagaatag atgaaagtta tattattaaa
    31141 agacgtaaaa ggaactggta aaaagggaga aatgaaagaa gtaagtgatg gatatgcaag
    31201 aaatttctta tttcctaaaa agatggctgt gcaagcagat agtgtagcaa taaaagaatt
    31261 aaatgaaaag aataaatcta aagaaataaa agcacaaaaa gagtatgaag aagcagtttt
    31321 attaggtaag caaatggaag aaattaatat agaaatatat tcaaaagcag gagaaggtgg
    31381 aagattattt ggttcaataa cttctaaaga aattgctgag caattaaaga aacaaaaaga
    31441 catagatgta gataaaagaa aaatattatt agatgaacca ataagatctt taggttcaac
    31501 tttcgtagaa ataaaaatac atcaaaaagt aactactaaa ataagagtgg atgtaaaaga
    31561 aaaacagtaa taactagagg tgattaagat ggaagatatg acgagaattc ctcctcatag
    31621 tgtagaatca gaacaatcaa tattgggttc tatacttcta gataaagatg ctataataac
    31681 ggttacagaa actataaagc ctgatgattt ctataaagag gctcacaaaa taatatatga
    31741 atgtatgata actttaagta ataaaggtga gcctatagac ttgataacat taacagaaga
    31801 actaagaaaa caagggcatc ttaatgatat tggaggaatc agttatatta caagtctttc
    31861 tactatagta ccgacgactt caaatgtaaa atactatgct gatatagtaa aagaaaagtc
    31921 tgtacttaga aagcttataa aagcttctaa tgaaataata aatctaggat atagtggagc
    31981 aactaagatt gaagatgttt tagaacaagc tgaaaagagt atatttgata tatcacagga
    32041 gaaaactagt gatgatttta aatctataaa cttagttttg atggatgcct atgatatgat
    32101 agaaaaatta tacactaaca agagtgatgt cactggtata actactggtt ttaaagattt
    32161 aaacaaaaaa ataaatggtc ttcaaaggac tgatttaata ttaattgcag ctagaccagc
    32221 aatgggtaaa actgcctttt ctttaaactt ggttcaaaat gcagccttaa aaggtgatgc
    32281 ctctgtagct gtatttagtt tagagatgtc taaggaacaa ttagtacaac gtatgttatc
    32341 ttcacaatct agtgtagaat taaaaaaaat aaagactgga acacttaatg ataatgattg
    32401 gcctagaatt atagatgcta tggcagtatt atcagatgcc aaaatacaca tagatgatac
    32461 tcctggtata aaaatatcag aactaaggtc aaagtgtaga aagttaaaaa tagaaaaagg
    32521 actagattta gtgcttattg attatcttca acttatggaa ggtgaaggta ataatgaaag
    32581 cagacaacaa gagatatcta agatatcaag gtcactaaaa atattagcaa aagaattaaa
    32641 ctgtcctgta gtagcactat ctcagttatc acgtgcacca gaacaaagag cagaccatag
    32701 acctatgtta tctgatttaa gagagtctgg agcaatagaa caggatgcag atatagttat
    32761 gttcttatac agggacgaat attatcatgc tgattctgag agtaaaaata taggagaagt
    32821 aataatagca aaaaatagac acggtgaaac tggttctgtg gaacttgttt ggcttggtga
    32881 agttcaaaga tttggggata agttgagaga cctataatct aacgaatatc cacagaacgt
    32941 cctttctttc tacaggaaaa atgtggatac atgtcactaa atatgtccaa acattgaaat
    33001 ttagctaaaa aactatccac actatccaca gatggcctgt tgataagtgt gaataagtag
    33061 ataaagcaag cttttggctt gctttatctg tgtataaata ttaattatta ggaggaataa
    33121 tatggaaaaa ataagcttaa aatatatata tcccaatata attaaagtac ttgatgaaat
    33181 aaacttattt agagtaattg acaataattt aagagaatct attgttgttt atgctaataa
    33241 tgtggataat cagtatcata taaacatgac taatacaaac tttggaaata taattaacat
    33301 atgtaaatta gaaaaacttt tagatgtgga taaatttatg gaaaaagtta taaaatatga
    33361 aaaagaaata atagagaaag aagagttttc aaaaatagaa gaatatatgt taaatattgg
    33421 agaatactaa aaaagttgaa aaaaatacga atgtttgata gaataagtaa gtaaagtgtt
    33481 cgagagtata taaaatatag aggtgaatta catgaaaaca gttgcaattg ttggttctca
    33541 atggggagat gaaggtaaag gtaaagttat agattatctt gctactcaag cagatgtagt
    33601 agtaagaggg caaggtggaa ataatgcagg acatacatta gttgtagaag gtaaaaaata
    33661 cgcattacat ctaattccat ctggagtttt aaatccaaat acagtgaata taatcggaaa
    33721 tggaatagtg tttgacccta aaggattttt agaagaattg gaaatgttta aaacggataa
    33781 tataagtaca gaaaatataa aaataagtga tagagcacat gtcatattcc catatcataa
    33841 agaactagat gcattgtcag aagaagccag aggcgattta aagataggta caacaaaaaa
    33901 aggtattgga ccttgttata tggataaaac agagagatct ggtattagaa tatgtgactt
    33961 aatggataaa gataaatttg ctataaaatt aaaagctcaa atagatgcta aaaatgaaat
    34021 agttaaaaat atatatggaa aagaagaatt atttgatttt gaaactatat ataacgaata
    34081 tctaggatat gcagagcaaa taagaaaata tgtggcagat acgtctgtta ttgtatatga
    34141 tgcagtaaga gcaggtaaaa aagtattgtt tgaaggagca caagggactt tattagattt
    34201 agatttagga acttatccat ttgttacatc ttctcatcca acatctggtg gatttgcaat
    34261 tggtgcaggt atagggccaa atatgataaa agacgttgtt ggtatagtaa aagcatatac
    34321 tacaagagtt ggagaaggac cgtttgttac agagcaaata aatgaaactg gagataagat
    34381 aagagaacaa ggacatgaat ttggggtaac tactggtaga ccaagaagat gtgggtggtt
    34441 tgatgcagtt atagttaagt atgcagctag agttaatgga ttgactagta tttcatttat
    34501 gttacttgat gtattaactg gatttgataa gataaaagtt tgtacgtctt ataaaatggg
    34561 cgataagata ataacggatt tcccagcttc attagatgat ttagcaaaat gtgaacctgt
    34621 atatgaagaa ttagatggat ggaatgaaga tataactcaa atagataact ttgatgacct
    34681 tccagaaaat gcaaagaaat atgtagcaaa aatagaagaa ctagttggag taagtgtaga
    34741 tatggtttct gttggtccaa atagagctca aactataata agaagaaata tatttgctta
    34801 atattttatc aattaaataa tttaaaatag ttgaagaaga gtatctcaag ataatgttta
    34861 tagttattag agatgctctt ttatatttga cttacattga ttttttatta agttaaagct
    34921 acttatacat attctaactg aaattaaagt tgaatttatg tagatacata taggtttttt
    34981 aaaaagaatt ttgttgaaaa taaatggcta aagatgattt taattatatt ctaaaaaaag
    35041 taaaaaaaac tattgactaa aaattatata gacgctataa tataacttgt gagtgaaaga
    35101 aacgacgaaa aaagtcgaaa aaatgtggtc tattagctca gtcggtagag cacctgactt
    35161 ttaatcaggg tgtcccgcgt tcgagtcgcg gatagatcac caaaatatgg ctcgttggtc
    35221 aagaggttaa gacaccgccc tttcacggcg gtaacagggg ttcaattccc ctacgagtca
    35281 ccagtatggg actatagctc agctgggaga gcacctgcct tacaagcagg gggtcacagg
    35341 ttcgagccct gttagtccca ccaaattttg aattagagat aaatactaga ttatatgctg
    35401 gtgtggctca acggtagagc agctgacttg taatcagcag gttgtaggtt cgattcctat
    35461 caccagctcc acaaagtaca taaattcaaa ttaatataat tttctatgtt acaggatact
    35521 tttaagtatc tttttttaat ttcattttta ttgtattaaa aatgaaatta aacatacaac
    35581 aaaattttga attacttgca atgtgatagt tttaaatata aaatttagaa tcattctagc
    35641 ataatattat gtaatatagc aaatttaatt tatagtatca ataaatatag actactaaga
    35701 atgtaaatga tttgttagat taaggtacat tagatatgta aatagaaaaa taaaaagtat
    35761 gttttaattt atgtgatata agttttaaac agagaagcaa gtttgctctt acctctctat
    35821 ttaaaaataa aaaaatgttt tttaagggct attttattta aatctttccc atctcaaatc
    35881 atctccagta aattctaaaa tcctaaactt atctaatatt ctagagagag ttctttgagt
    35941 gtaagtattt cctatttgag atggtgttaa gttggttgaa ataatgattt ttttaccagc
    36001 aacaagtctt gtatttacaa tattgaagat ttctccacta gtaaaagaat tattaagttc
    36061 agttccaagg tcatctatta ttaataaatc acaatcaaac aagtttttat aattatcttc
    36121 acttatttga ttatttgtgt ctcttctaaa tttataatct tcaagaatat ctaaaattct
    36181 aaaagaagtt tgatagatta caacattgcc tttatctaac aattcctttg caatacaatt
    36241 gcacatatag gtctttccta gtccagtaga accataaaac agtagatttt cactattatc
    36301 cttcttaaaa tcatgaacaa aattttcgca gatacttaaa ttatttagca tattttctct
    36361 aggagatatt tcaccatcag agcctttctt aggagaaaat atattcaagt taaaattcga
    36421 aaaattttcc tgacttaaaa tcctatctaa attagacatt ttataagctt catttacaat
    36481 ttcttgtttg aggcaagaac atttttctcc attaggtaaa aatcctttat ctttacaaga
    36541 aatacattga aactttattt ccaagtaatc aagaggtatg ttactttcag ctaaaagtct
    36601 ttctttcttt acttttaaag attctatatt ctctttagtc ttctttacaa tttcatcttt
    36661 agacttagga tttaaaagta ctatcttagc taaactgaga cctattttag aaatttcatc
    36721 atctatagat tttatctcag ggattctatt atatacctca ttttttctat gttctaataa
    36781 gagttcatta tcatctcttc tcttagcata tttagcaagt atttttctta ttttatcctc
    36841 attcatttaa tcacctactt aaacttttct ttttgacttt ttttaataat ctcatcgagc
    36901 tcatcagagg tatactgagt gaatgtttcg ttgaaattat gaaacttagt ttttttgtaa
    36961 gtattgttgt tttgagtagt attaatctgc ttcttattaa tattctcctt aactatacgt
    37021 tcttcctctt tttgctttaa atcatttaaa ttttttatat ttttttcatt ccaattttta
    37081 attataccat ttatataaga tatacttggg tttgaaatat tcttagactt agaacatgca
    37141 tttattatca aatctatatc catattaaat ttatcaaacc aggtgtccat aagttctttt
    37201 tctgattttg atggttgtct tgaaaatccc aattcattga aaatcgtttt atataaaata
    37261 tatcgttcac ttcttaccaa aaagctttct tcaacatctt ttggcgtata taaatttgaa
    37321 tcataccaat ttctaataat gccttcaatg tatttaactg gctttgatgt accagtttta
    37381 tctttgacgt attcatatgc gcaaagtatc atatcggggc tcatattgta tttattcatt
    37441 atatccataa tactcatctt ttcacttggg tcgagatatc gcccaactat tttatttata
    37501 gaattaaaca tttttctaat acttggattt tcagaagtag atacaacttt atctgtatta
    37561 gattttatag atgaattatt gcttaatata ttctcaatat agaaattttt taaatctaaa
    37621 aattctattg aataattaaa attatcatat tcttcattgt catgtatttt tataatcttc
    37681 ttttcttccc agaatttcca agcagataac acatcagaca atggtatatt taggtttttg
    37741 gctattgaat tattgtcgaa cttaggatta gaagtaatat cacatgcttg tctatatcct
    37801 aaaagataaa cttttacgta taacccgtcc gccattggca taaatatatc tataaagata
    37861 ttgggaatag tgatttcacc taaatctatt tcattgcttt ctttaaaaaa cattttatca
    37921 cctcagatta aattatatca ttttttatat tatatttgtc tgtaaacaaa taaaaggtca
    37981 caagattagc atgtaaatat tttctaaaag tattcatttt gaaaaggagg agatattttg
    38041 gttataaaat tcaaccaaaa agtaagaaga acattatcag tagcgattct atttatggta
    38101 ttaataatag gttgctttat agaaaaggat gacagtttag aaacatacaa agaaaaaact
    38161 aattcaaaaa taaatcagta taatatggat gttatatttg atgatgagac taagaggtta
    38221 atgtgcaatc agaatgttga ctacataaat aatacaaaat caaacataga taaaatatat
    38281 ttccatatat atccgaatgc tttttccaag aaagattttg ctccttttga aaaaagtgaa
    38341 atgacaaggg cttatcctaa tggatttaac gaaggatata tagatataaa gaatatatta
    38401 aataataata gtaaaatgga gtataaaatt aaaggagaca aaaatgacat attagaaata
    38461 gaattaggga aagagttaaa accaaatgaa agaatgtcat tagatataaa atataacgta
    38521 aaaataccaa attcaattgg aagatttgga tatggagaaa atactataaa tgttactaat
    38581 tggtttccta tagcttgtgt aaatgatgaa aggggatgga atttaaagag ttatgaaact
    38641 attggcgacc cattttatag tgagactagc gattttcatg tgaaactatt gattccaaat
    38701 aaatataaaa ttgctcatac aggaaaactt attgatgata aacatgataa taagaaaatg
    38761 ctatatgaaa tagaagctga aaacgttaga gattttgcat ttatactaag tagtaaattt
    38821 gatgtaaaca aagtagattc aaagggagta gctatcaata catataattt aaataaaaag
    38881 ctttctaaaa aagcaactga agtggcaaaa gattcaataa atatatttag tgaattattt
    38941 ggaaagtatc cttacaaaga attttctgtt gtagcaagtg acttttttat aggggggatg
    39001 gaatacccta tgcttgttat gatagaccaa agtttatata atgaaaaaaa tgaattttta
    39061 ctagaatatg ttattgccca tgagacagca catcaatggt ggtattctgc tgttggaaat
    39121 gatgaaataa gtgaaccctg gttagatgaa gcacttactg aatattctac aatagtttat
    39181 tttgaacaaa agtatggtaa agatatggca aacaagctta taaaaactat ggagatacag
    39241 acaaaaagtt atttgagtga aaatatattt aagccagcaa atgagtataa aaattctact
    39301 gaatacagct tgaatgttta tacaaaaggc gcaatagcat ttaatgaaat aagaaaagaa
    39361 gttggagata aagtattctt tgagacttta aatgagtact ataataaata taagcataaa
    39421 aatgctaatg gaagagcttt tgtggaacta tggaatagta aaggtgtaga tataaataag
    39481 attataagtg aatgtaagta aatagtgaat gtaagtaaat tttgtgcaga gtattaaatt
    39541 ttatttaata ctctgttttt ttggtataat ataatttata aggcagaaaa agaggtgaag
    39601 gaatgctaaa gtattgttca gtagggagtg gtagtagtgg taattgccac tatatagggt
    39661 ataaaaatac taatatacta gtagatgcag gattaagtgg caagagaata actacaggtc
    39721 ttaaagacat tggtgtagat gcagataaat taaaaggaat atttataaca catgagcatg
    39781 ttgaccatat aaaaggagca ggtatattat caagaaagtt tgatatacca gtatttgcta
    39841 atataaaaac atggtgttct atgaaggaca aattaggtga catcaaagat aaaaatatga
    39901 aagtatttga aaatgataaa acctactcat taggtgatat catagtaaga cctttttcaa
    39961 tagaacatga tgcgtctgac ccagttggat ataattttta tacagagagt gatgaaaaaa
    40021 tgtctatagc tactgatata ggatgtataa ctcaaaatat aaaaaaacat ctatataaat
    40081 ctaaattagt agtattggaa tcaaattatg accctaatat gcttatgatg ggttcatata
    40141 catatgcttt aaagaaaaga gtaatgtcaa gtactggtca tttatccaat gaagatgcag
    40201 ctaatttctg cgttgaactt attaatgaag gtacagaatc tatattatta gcacatttaa
    40261 gcaaagaaaa taattttcct gagttagcgt atgagacttc aaaaggagta ttagcatcaa
    40321 atgatatagt agttggacaa gatgtaaaac tagatgtact atcacgaaat gatgtttcta
    40381 atgtttatga gatgaagtag aggtgaataa ctttgctaaa gagaaatttt gaaaatgttg
    40441 aggataataa aattttatac tctataaagc agggtatgat tttagcgata cctgctatta
    40501 tgactggttc aactgctctt gtaattttga atcttccaat aaaggcttat caagaatatt
    40561 tatcaggctt gtttaatgga gaggttacaa atattcttaa ctttataaat gattctactt
    40621 taggaattat ttcattaata atattattaa caataagcta tagttatgga aaaatatatg
    40681 ggagcaagta tacagtactt gttcctatag ttgcaatgtg ctctttttta gtattttcac
    40741 atggtaatga gcttaattct tatatagaaa tatttaaaac aaagtggtta tttacatcta
    40801 taattgtttc tatgacatct tctgtattgt ttgtaaaact tacagaatct tttgttacaa
    40861 gtgtaaagtt tcatacagaa ggggctgatg cagactttaa tatggtagtt tcggctatag
    40921 ttcctttcat aatagtagta tttttgtttt ctatttttag agtggtaatg ataagtctaa
    40981 ttggcagttc aaactttcaa gatatatttt ataatttatt ttcaaatgtt tttaataaaa
    41041 tgggaacaaa ccttatgagt gctctgttgt ttattttttt aatgcacttt atgtggtttt
    41101 ttgggattca tggtagtaat gtattagata ccgtcgcaaa aaatttattt gaaaatagta
    41161 tggcaattaa cataaattta gttaataata atcaattacc aacagaaatt tttactaaga
    41221 ccttttttga tacaatggtt ttattgggag gatgtggctc tttactatgt ttagtaattg
    41281 caatttttct tagtgaaaaa cgtataaatg taagaaagtt agctaaaatt gcttcaatac
    41341 cagctctttt taatatcaat gagatgctag ttttcgggat accaattgtt tttaactata
    41401 ttatgtttgt accttttgta attactccta taatcttaac cgttacaagt tatgtggcta
    41461 tgtctacagg tattgtacca tgtacagttt cagctgtaga atggacctca cctatatttt
    41521 taagtggata tatgtctaca ggttcaataa gaggtagttt gttgcaagta tttaatttat
    41581 gtgttggtgt tatgatttat attccgttta taaaaatgtc gcaaaataga tatacatata
    41641 tgtttaaaaa taatatagaa aatttaacaa acttattaaa aaggtatgaa ttaacaggtg
    41701 aacagcctaa tcttctaaac cataatggta aaataggttc aatttcaaaa atgttggcat
    41761 cagacttgaa gtttgctatg aaaagaggag aaatagagct tttttatcaa ccacaagtca
    41821 attataatgg aaatgttgtg ggagcagagg gattacttag atggaaacat tcaataggag
    41881 ggttcattta tccaccacta gttataattt tggctaaaga agaagggttc ttagatgagc
    41941 ttggagagta tattattaat aaagcatgta ttgatttaaa gaagagtgaa aagctattga
    42001 gaaatcctgt taagttctct gtaaatatat ctccagacca acttgatgac cctaagttac
    42061 cagagcaaat aaaaaatatc attagtagta atgatataaa tcctaatatg ttaggtatag
    42121 aaataacaga gcaaattgca ttatcaggtt cacaaataat tattgaacgt atcaatgcga
    42181 tacataactt gggaataaag ttaattatgg atgattttgg gatggggcat agctctctta
    42241 tatatcttca aaataataac tttgatatag ttaaattgga tggttcatta gttaaagaga
    42301 tacttacaaa taaaagaagt agtgaaatta taatgactat tgtaaatctt tcaaaaaatt
    42361 tagattttga tatagttgtt gagtatgttg aaaatataga ccaaagggat aagttatatg
    42421 gtttaggatg tgaaatatat caaggatatt attatagcaa agcaatacct tttgaagagt
    42481 ttgtagaata tgcaaatcaa gaaagagaga tataatttta taagagcttg taaattctag
    42541 taatgcatag atttgtaata aaattaagtt taggagaaat atatgaatat aagtatagta
    42601 gtagtaggta aaattaaaga aaaatattta aaattaggta ttgatgagtt taagaaaagg
    42661 ctttctaagt attgtaagtt agaaattata gagttggatg atgaaaaagc tccagagaat
    42721 ttgagtgtta aggaaatgga aattataaaa gacaaagaag gaaagaaaat tttagggaag
    42781 ataaagcata atagttatgt tatagccttg gctattgatg gtaagggttt atcctctgaa
    42841 gagcttgcta agactatgag tgatttagca gttagaggta atagtagtct ctgttttata
    42901 ataggaggtt ctttagggct ttctgatgag gttttaggaa gggctgatta taggttatcc
    42961 ttttctaaga tgacttttcc tcatcagatg atgagattga tattgttaga acagatttat
    43021 agggcttata ggataaataa tggagaaccg tatcataaat aaatgatacg gtttttgtta
    43081 atttgacact taataatatt aaaataacaa aaaagtattg aaagtatatt gcatttaagg
    43141 tagaattaaa taaaatatta taacattata atgtttatat ggttgttaat aaaaatttgg
    43201 aggaaaatat atgataaaaa taatgttggc ctgttcagca ggaatgtcta caagtttatt
    43261 agttactaaa atggaaagtg cagctaaaga aaatggtata gagtcgcaaa tttgggcaat
    43321 accagaatca actatacaaa atgaaataga aaaatgtgat gtattattac taggaccaca
    43381 agttagatat gtattaccta aggctcaaga aattgctaag ccatataata taccagtaga
    43441 agttataaat atgatgcact atggaacagt taatggagaa gctgttttaa atagagcgat
    43501 agaacttaac aacactaagt aatataaatt ataatgtatt tttaatatat aaattgggag
    43561 aatcaaagga tggatgaaaa gactatagaa atatctttta atataatagg ttatgcaggt
    43621 gaaggtaaag gattagcttt tgaagcaata aaagaggcta agaatggaaa tatagaaaaa
    43681 gcaaaagaat tattaaaaga gtccagggaa gttataaata aagcacatag atatcaaaca
    43741 gaattaatac aaaacgaagc tagtggaaac aggactgaaa taagtgtcat acttatacat
    43801 gcacaggacc acttaatgaa tggcatgaat tttcaacagt tagctgagga aatcgttgat
    43861 ttacatttga aattacaaga taaataaaaa ttaaagataa taaattaaga gagttcttaa
    43921 aagatacatt atgtgtagca cactaattgt tagattattg attcaatatt tagtgagtaa
    43981 tacattagga ttattttgag gactcttttt atatttagtt taaagttaat aaatatttat
    44041 tattaataat ataagattat atgttataat attataacat ataatttaag aggtgaatca
    44101 tgttaagaaa tcaaccatta tatatacaag ttgtagatat attaaagcaa aaaatattaa
    44161 ataacgaata taaaattgat gaaaatattc caacagaaag ggagttagag caagagtttg
    44221 gagtcagtaa aattactatt agaaaagcta ttgagatatt agaatcagaa gggtatgtag
    44281 agaaaaaaag tggaaaaggg acaaaagtaa taagtaatag tctttttaat aagctatcaa
    44341 aagcagagtc tttttcaagt atacttttat ctaaaggtca taagttatct aaaaagacta
    44401 tttcaattga aaaaataata aatgatacaa attcacaagt atttagtata tttggagaaa
    44461 aatgtagcaa gattactaga atgtattact tagatagtaa gccatatata ttttttactc
    44521 attatattcc ttttgatgaa aatctaactg ttgaaagttt taataatgaa agttctttat
    44581 atatgtactt atataggaga aatataaata taactagatt tgaagatgaa ttttttatag
    44641 aagaatcaga actagaggta tcaaaggctc taaatctagc taaagacata ttattaggaa
    44701 gaaaaagaaa gacctatgat gagaatgata atatagttga gctatcattt gcaagatata
    44761 atacagaagt acaaaactat gtaattaaat acgaaatata ataagaatcc tgagtttatt
    44821 gaaatgataa tatgctcagg atttttgttt agttgtaaaa ataaaaaata ttataacatt
    44881 ataatgttta caactaaaca ttataatgtt ataatatttt taataaacaa gtgatattat
    44941 caattacata aaaattagtt tatgttatga aatcgttatt gcattataaa taaaggataa
    45001 tatcaataat acagggggat aactatggaa aaattcgcaa gttttttaga gcgcaagatt
    45061 atgcctgtag cagcgaagat aagtaatcag agacatatga gagctgtaag agcaggtata
    45121 atagcaacat taccactaac aatagtgggg tcatttttca caatattatt aaacatacct
    45181 attgatgctt atatggattt tatagctcca tttaaagcaa tattagatat accatttaga
    45241 tatactgtag gatttttatc tctatatgct acttttggga tagcatcatc acttgctaaa
    45301 agctacgatt tagatacaac aggtgttggt atgcttgcag ttatggcatt tttagtttct
    45361 acaatagttc caactcaagt agttgaacca gtaggtggag ttatagaagc tggtagatgg
    45421 atggatatgg caaaacttaa ttcgccatca ttatttggag ctatcgtaac atcattaatt
    45481 acagttgaaa tatatcgttt tatgaaggaa aagaatatta caattaagat gccagcagga
    45541 gttccagtag aggtttcaaa ttcatttact gcattattac cgacagcagt aattttaatg
    45601 ttattctggg taataagaca tattttagga tttgatataa gtgttgcact aagcgctatg
    45661 ttatcacctt taaaaggatt cttatcagga aatagtttag gtggtgggtt actgacagta
    45721 ttcctaataa ctttattctg ggtacttgga atacatggtc cagctataat ggggccagta
    45781 ataagaccta tatgggacat gtctatagca gaaaatataa ctgcattcac agaaggagta
    45841 tcagctcatg caatgccaaa catatttaca gaacaatttt tacagtggta tgtatggata
    45901 gggggagcag gggctactct tgcattagtt gtaatgttta tgttttctaa gtcacaatat
    45961 ctaaaaagtt taggtagatt aggattttta ccagggttat tcaacataaa tgaacctata
    46021 atatttggag caccaatagt tatgaatcca atactaggga taccatttat aattggacct
    46081 ataataatga caattctatc atatgttctt actattacag gggttatacc tatgatggta
    46141 gcaagattac catttgcaat gccagcacca atagcagcag taatgagtac taactggagt
    46201 atattagcag gtatcttagt attaatcaac tttgtgatat catttgctgt ttattatcca
    46261 ttcttcaaag tttttgaaaa acaacaatta caaagagaac aagaagaaat gagtgaaaat
    46321 ttataaaaat acatagatat agaggttttg tactatataa aatatagaaa aaacttataa
    46381 gttattaagg gtgaaggtag gaggaatgac ctttgccttt aattttatat attttaaata
    46441 atgtaatttg aggaggagaa agatggaaag aagattagga atatcagtat atccagagca
    46501 tagtaacatg gaagatgata aggcatatat aaaaatggct tcaaaatacg gatttaaaag
    46561 aatatttatg tgcatgcttt caattacaag acctaaggaa gaagttaaaa aacattttaa
    46621 agagattata acctatgcaa gagaattagg atttgaagta atccttgata tagctccaaa
    46681 catatttgat atattacaaa tatcttatga tgatttaaca ttttttagtg agttaaatgc
    46741 tagtggaata aggcttgact atggatatga tggaagtaaa gaagctatga tttctttcaa
    46801 tccatatgat ttaaaagtgg aactaaatat gagtaatgat gtagcatact tggataatat
    46861 aattacttac aagccaaatg taaataatat atatggttgt cacaattttt atcctcaaag
    46921 gggtacaggc ttgccatatg atttttttgt aagatgttca aatagattta aaaagtatgg
    46981 aataagaact gctgcttttg ttaattcaaa atatgcaaca atcggacctt ggaatataaa
    47041 tgatggactg tgtacgcttg aaatgcatag aaacttagat attgctacag caactaagca
    47101 cttattcgca acaggattga ttgacgatgt aattgtaggg aatgcatatg caagtgaaga
    47161 tgaattaaaa agaatgtctg aagtaaataa atatcaagtt gtatttaatg tagtaactga
    47221 ggaaaaaact tctgaagtag aaaagacaat aatggcaaat gagcaacact ttagaagagg
    47281 ggatataacc aaccaagtag caaggtctac agaagtaaga aaaaaatatg ctaaagaaaa
    47341 tttccctaag catgataata cgaccatctt taaaagagga gatgtagtga ttggtaatga
    47401 tgactttgga aagtataaag gggaattaca gttgatactt caagattgtg cagatgaaag
    47461 aaaaaataag gtaggtagaa taaaggaaga cgaaataatg cttttagact ttattgaacc
    47521 ttggagtaaa tttaaactta ttttagaggg agagtaaagt gaagatagac atattaataa
    47581 aaggtggaaa aacagtagat aaaagtataa ttgatatagc tatattagac gataaaataa
    47641 tagaagtaaa aaatcagata gatgattcta agtatcaggc aaatcaaatt ataaacctag
    47701 atggagaaaa atttattagt gctggttgga tagatataca tacgcattgc tacgaaagac
    47761 tagaccttta taaggattat ccagatgagg ttggaataaa aagcggtgtt actactgtag
    47821 tagatgcagg aacaacagga gctttagata taggtaaatt ttatgaagat actaaaaaat
    47881 ataaaacaaa tgtatatgct ttaataaata ttgctaagca gggaataaca tctcaagatg
    47941 aactttcaag tatgatgaat attgatgaat atgaacttaa aagagcagtt aaaaaataca
    48001 aagattttgt tgttggaatc aaagctagaa tgagtaaaag tgttgtaatt tcaaatgatg
    48061 ttgaaccttt aaaagtagct aaaagaataa aaaatgaact taatctacct atgatggttc
    48121 actttgggag ttctcctcca acgatagagg atatatttga ctatatggaa aaaggagata
    48181 tattaaccca tatatataat ggaaagccaa atggaatact tagaggcaat gaggttaaaa
    48241 aagaaatcat agaagctaga gaaagaggta taatccttga tgtaggtcat ggaaccgaaa
    48301 gttttagtat ggatattgca atgaaatcta aggatgcagg aatttttcca gacactataa
    48361 gtacagatat atatattaaa aatagaataa atggtccagt gtataatcta tctacaacaa
    48421 tggaaaagtt tatatatatg ggctattcac ttgaagatat aatagataaa gttactaaaa
    48481 atgcagcaga tgcaataagt ttaaaaaata aaggtttaat aaaagaagga tatgatgctg
    48541 atttaactat atttgatgtg gttaatgaag aaaaagaact tcaagattct ttgaataagt
    48601 cagtaatcac aagtacgtct ataaagccaa gagcagtagt agtcaatgga gaatatttaa
    48661 atataggtaa gtctatagga gagaatgagt agaagggaga aactattgta tgagtagtat
    48721 atttgaaaaa tactctgtaa gacgtgttat aaatgcttca ggcaaaatga ctatactagg
    48781 agtatcaaca gtagataagg aagttattga agcaataggt gaagggtgta aaaatttctt
    48841 tataatagaa gaacttataa ataaaacagg tgaatatata gcaaatttat tagggtgtga
    48901 aagtgcacta atagtttcta gtgcatctgc tgggattgca cagagtgtgg gagcaatgat
    48961 agcaaaagat gatatgagtc tagtttacaa tgtaaataat cctaagaaac aagttaaaag
    49021 ggaaataata attccaaagg ggcataatgt tgattatgga gttccagtag aagtaatgat
    49081 aagacttgga ggaggagaag ttgttgaggc cggctatgct aatatgtgta acaaggaaca
    49141 tataataaga gagataaatg aaaatacagc agcaattatg tatattaaat ctcatcattg
    49201 tgttcaaaag agtatgctaa gtgtattaga tgcagtacaa gttgctaaag aatataattt
    49261 acctttgata gtagatgcag cagcagaaga agatttaaat gtatattatg aattgggagc
    49321 agacctagtg atatacagtg gtgctaaggc tatagagggt cctagctcag ggttagtaat
    49381 aggtaagaaa aaatacatag ataatgtaaa gcttcaatca aagggtatag gaagagctat
    49441 gaaaatagga aaagaaaata ttgtaggtct aacatgtgca attgagagat atataagtaa
    49501 tgataaagta actttaaaag aaatggagga caagctaaat ccatttatag acaagataaa
    49561 tactataaag ggagtgagtg ctagtataac tagagattca gcaggtagag aaatacttcg
    49621 tggagaaatt gactttaatg aagatataat aaataagtca acacaacaaa ttataaatga
    49681 acttagaagt ggagagatag ctatatacac tagagactat aaggctaatg aaggcaagat
    49741 tgagattgat ataagaagtg taactggaag tgatttagat actatttata ataggataaa
    49801 aaatatagta gaaagttaga gtgtagagta agtgacatta taatgattta ataaattaaa
    49861 ttttaccaat ggaggggata aatatgaatt gtataccaca atattataaa aatagagttt
    49921 gtttaaatgt tcttgcagga agcataaaaa atgctaaaga agtatatgat gcttgtgatg
    49981 ggtatgtatt gataggagta ctatcaaaga attacagtac tgtagaagca gctattgaag
    50041 atatgaaaaa atactcaaag gaaatagata atgcaatatc tgtggggctt ggagctggag
    50101 acccaaatca gtcaaatatg gtatctcaga tttctaaaga acttcagcca caacatataa
    50161 atcaagtgtt tacaggtgtg gctacgtcta gagcattgct tggtcaaaat gatagtataa
    50221 taaatggatt agtttctcca actggtaaac caggatttgt aaaaatatcc acaggtccat
    50281 taagttcaaa agaaaaagat ggtatagttc ctatagaaac agcaatagct atgatgaaag
    50341 atatgggagg aagctcaatt aagttttttc caatgggagg gcttaaaaca aaggatgaat
    50401 atatagaagt tgcaaaagct tgtgcaaagc ataattttta tttagaacca acagggggta
    50461 tagacttaga taacttcaaa gagatagttc aaattgcact tgatgctggt gtagaaaaag
    50521 ttatacctca tgtttataca tcaataattg ataaagaaac aggtgaaacg aaagtggaag
    50581 atataggagt actttataaa ataatgaaag aattattggg atagatttat gaatatatta
    50641 gcttttggtg aaataatgat gagactttca gtacctgact acaagttctt aacacaaacc
    50701 aatgaactaa attatataat tacaggcaca ggattaaata tattatctgg acttaaaaac
    50761 tttggataca atacctatat gttgacaaag ttgcctaata ataatgtagg taaagcatca
    50821 agtgcaaata taagaaagct tggagtaaaa gatgacttta tcacatatgg agggaatcat
    50881 ataggagtgt attttcttga aaatgggtat ggagaaagac cttctgaagt gacttatttg
    50941 aataggttaa atagttcatt ttgtgagagt aaattacaag attatgatat tgataaatgt
    51001 ttagaagaaa tggatatagt ccttatttgt ggtattgcta tgcaacttac agattcaatt
    51061 aaagagattg ctttagaact agctagaaaa tcttatgaaa aggggataaa agtattcttt
    51121 gattttaatt ttagacaatc attaaatcca gaaaggactt atgatgattt agtaaatgat
    51181 tataagaaaa tactaccata ttgtcatggt ctatttgcta gttatagaga tataaataag
    51241 atacttaata tagatagtct aaatataaaa tctagttcag aattgattaa aaaagagtat
    51301 gatataggta ttgtagctgg aactatgaga agatttgatg atatgaataa tagatttata
    51361 aagggatata tatcaaatga tgatggttat tttgaaagta gggagtataa gttagaaata
    51421 tatgacaggg ttggtgccgg agatggatat gtagcaggaa ttatatattc atatttggaa
    51481 aatatgaaga gtgaagatat agttgagttt ggggttgcta gttcggtgtt agctcataca
    51541 acttatgggg ataattcttt agtaagcaca ggtcatgtac ttagacttat gaacaatgaa
    51601 aaaatagata tattgagata atacatttgt atataataaa atttttatct tttttagaca
    51661 cacttttgac ttgtttatat ttgttaaaca gagttatttt taatgattat aaatattaaa
    51721 ttaaaagtta aataataaaa tagtagaaaa tagcattaac tatagaaaaa atggttaatg
    51781 ctatttttat cgttaatatt gattaatttt atattataga aatgaacttt tctaatgctg
    51841 gatttgtatt ttttttattc catacaacta caacttcaat tctattttct acttctttta
    51901 taggtactat tgcaatatca cgttctatca ttgtatctgt aacacaaaat gaaggtaaaa
    51961 tggatattcc catgttagaa gataccaatg attcaatagt attaagatta tttgaacgtt
    52021 gtaccacatt aggtacaaac cctgcttcac gatatctatt ctgtatcatt gacttttgtc
    52081 catactcatc ccctgtttct tttacaaaaa taaatttatc atgttgtaat tcaattaaat
    52141 cgatagaatc ctcattgtaa agtggatgac caggaggtaa aagagctacc aaagaatatc
    52201 tttctacagt tttatattca aaatctttta atggttgatt ttctggatta ataacaaaag
    52261 cgaggtccat agaattattt tttactaagt ttaaaagttc ggttatttca ttagtacaaa
    52321 tatccataga tatattaggg tatgtattag aaaattcttt taaatattgt tgaagtttgt
    52381 ttttttcata tcctattaag gttccaatgc tcaaagttcc aaaaaaacca tgtgcaaatt
    52441 gttgtgtttt tgcaatagca tcattgatat tttttattat agtacgtgcc tcagataaaa
    52501 aaacttttcc agctggtgtt agttcaacat gacgtttact tcttgtaaat agagttacat
    52561 ttatttgttc ttctaaagct tttatttgct gtgtaacagc agtttgagaa atataaaatt
    52621 tttctgctgt tttggtaaaa cttaaatttt ctgctacaga tataaaatat tctaattgtt
    52681 tagtattcaa ataatcaccc ctatttaaac ttgattgttt gtaaacctta tttatctata
    52741 attaaagctt attatagtat aagaaaattt acttttaaag aatattagaa aatatttgta
    52801 taaaaatata tgttttaagt atatctttac attagatttt ataaatttat taataagaat
    52861 aacttatata ttccaatgaa aacgatattg gatttaagta agtttgtctc ataaaatgaa
    52921 agtatatcaa ttgataatac tttaaataag aagggagaaa aaatggaaga taaattttat
    52981 gcaaaaggca acggaaataa cggatatatt aaaaatcttg aagtttgttc ctttaataac
    53041 ttagatggaa cttgtggaat gtttcaaatg gctctgtaca aaagagatga aaaatactat
    53101 ttatatggat gctgttttgg aggaaataaa aaaaatggag taatgattag cgatattaca
    53161 gacccttata atccacaatt tataaaacat tttcaaatgt tagaccctaa agagtatcct
    53221 acaacaacaa ctcccaaaat tcaaatagca gatgatttaa tgatagtagc aatgagttgt
    53281 ggaagtggac caggagcact tgttgaccaa gctaaattag caaatattaa gtgtgaagca
    53341 ggaattagaa tatatagttt aaaagaagac cctttaaatc ctaagttttt aggatattgg
    53401 gattgtggct taaagcatgt aatgggtgtt catagattca tgtacaatgg tggaagatat
    53461 gtacatttat caagtgattg tgttggcttt gaaggtctga tttatagggt catagatata
    53521 ataaatccta ctaatccagt ggaaataggt aaatggtgga gaccagacca atatgcagat
    53581 ggatatccaa atagaacttt tgatgcagga gcacctcatt gcccagaatt tatggataaa
    53641 ggatggcttc atggacctcc atttgtaaga gacggaaaag catattgtgg ttatggagga
    53701 gctggtttag ttgtattaga tgttgaagat ttaacaagac caagatgctt aggtgaattg
    53761 ccatttatgc ctgcattttc tagtagactt gcaggtgcaa gaactcatac agcattacca
    53821 ttgccaggaa gagatttagt cgttgttcaa aatgagggag aaagattcca gttctttaaa
    53881 ccagataaca ttacagatgt tcaagctatg aataatatac atatggttga tgttagtgac
    53941 ccaacaaaac caacattaat tgctcaattt ccatatcctg aagttccaaa agatttccct
    54001 tatcctaact ttaatgttgc aggattagga aaaccagggc catttggtcc acataatctt
    54061 catgaaccaa tggataataa accatggtta gagcaaagag gagatagagt atattgctgt
    54121 tatttccatg cagggctaag ggtttatgat gtatcagacc catattatat caaagagcta
    54181 gcatatttta taccaccaaa tccaaataaa acaccagaag aatcttattt cccaggattc
    54241 ccaggaccac gcttggcagt aacagaagat cttatcgttg atgatagagg ctacatcatc
    54301 atagatgctt tagatgatgg attctatata ttaaaaatga aagaagatta aataaatact
    54361 aaagagggag agttgaaaat gaaaatacta ggtatttctt ttggaacaaa aaatggaaat
    54421 aatgacacaa tgtgtaaagt tgcacttaaa ggtgccaaag aagcaggggc tgaagtagaa
    54481 tttattcaaa tgtcatctat taacattaaa cattgtactg gatgttgtgc gtgtgttaaa
    54541 actttattat ctgggaaagg tagtatgtgt gtattaaaag atgattttga atggttgctt
    54601 gacaaaatga aagatgcaga tggtatagta gtttcagacc ctatttttga agaaggggca
    54661 tcaggattat tccatactat aatggaccgt tttggaccca gagcagatag aggaaataac
    54721 attataggaa caaaagttgc agaagctata ggaggaaaaa ttccagattc aagaatgctt
    54781 aatgataaag taatatcatt tatgggaata ggaggttctg actggggtac aagagttcaa
    54841 tgtgaacatg ctatgctagc tctcatacca atgtggaaag ttatagataa tgcttggttc
    54901 ccatgggcaa aggaattagt aatggatgat acaaggcttg ttcaagttca tcaaattggt
    54961 ttaaatatag ttgaagcagc aaaagatttt gaaaaagctt catatcaagg agaagaaggt
    55021 gtatgtccac attgccacaa tagattattc taccttgagc caggtactaa aaaggcaatt
    55081 tgtgctctat gtggtatagt tggagagtta gatactataa gtggaaaaac tatatttagt
    55141 tttccagaag agcaattagg tcatgctcat gatactttac caggtaagtt tatacatggt
    55201 gatgatatta agaaaatgga aggtcattat gcagaagttc gtaaaacaca agaatttaaa
    55261 gaaagaaaaa catcttataa ttttatagag acattaacta aagaaaaaca agctggagtt
    55321 tcattaggat aataattaaa atactaagac tcttttttaa gggatgttag atgttatagg
    55381 aggcttattg tatgaatgaa aagccaagtt ttaaacaaat tgaagttatt ttagcagtta
    55441 tttttttggt acttacatat tacaaggtta gattaactcc agcatttatt gttatattta
    55501 taccactata tttaagttat tttgcagtat ctatgattgt aaatcaaata gcaattaagc
    55561 tattggagat aaggcaagct agggaagcta ctaattacaa tataggaaat ggatagaaag
    55621 aaaaaagaaa tattaacact gtctatgggg attgctttac tacctccttt atgggcagta
    55681 ttagcacctt atataggaat aaaaactgga gctgtagcac taatctgtgc aggattatat
    55741 gtaactaatg gtaataaaca agaagatgga ttaaaaataa tgtttggttt ttggtgtgga
    55801 gatttatggg cagtgttagc cattttaatt atgggatata tgaatttcaa tcaaaaccta
    55861 gaattatttt taacacttag tatattaggt ttttttgcag ttgtaattgc atccttattt
    55921 gaaaaaataa ttttcctacc atcatggctt tgtggttggg ctataggtct aactattatg
    55981 acaggtgaaa atattattaa tttacaagat atttgtattc aaattgctgt agctatggca
    56041 gtaggagtat ggtacgtggg tgcaggtgta gatttgttta caatatatat tttgagtaaa
    56101 gataggaaaa agggaaattg aaagcatgtg aatatacttt gattatagga ggatggctat
    56161 gggttttgaa tttaaaataa tgagaagttt aatatatgta ggacttgcca aggaagaata
    56221 tagacctaag ctaatggact ggttatatcg tcaccatatt ccagatagta ttagcacttt
    56281 tggaccatat tgtactaaat atgcctttta tcaagcatat cctacaccaa atgaaggtga
    56341 gcgttttggt gcacgtaaga tgcaactaac agaacattat tggcttgtag atgaacatat
    56401 gcctgagatg gcaaatagaa ttatgacaga atatatgcct atggatgttc tacgttggca
    56461 agggtgtata ccagatgtag aaaataaaag ggttcatgaa aatgcagaaa gtggagatgc
    56521 aggacgtgca gtaggtggag ataatggatg tccaccattt atatttgcct ttgttccaat
    56581 aaactgggaa gaagacttta gaggaaaagg acgtactgta caagatggac caaactatcg
    56641 ttggcaattt atgattaagt atccagatgg tatctctaaa gaagaaggag aaaaatggtt
    56701 ctatgatgag gtagtgccat actttacaaa ctgttgctat gttaatcgtt ttgtcagtag
    56761 taaaataatg attaattatg gagcaactgc ttttgaccgt gtgtcagaac tatggtttga
    56821 aggggaagaa gaatggtata aagctgtggt tgaagagaca aagtcgttta ttaaaaaacc
    56881 agaatgggca caagaagagg agttcccata tttaaaacca caattcaata tcgcatcagt
    56941 attcttaggt gatatagcaa ctatggatgc atactcacag tatcgtggat atataccaat
    57001 gagataaaaa ttatagtttg tgataagtag agaaggcatt tactcttact ggtagaagaa
    57061 gacttattgt atccttaaaa gtaggtgaat atatagtttt atatttaaat ttatataaaa
    57121 ctaagactaa taaatatgaa acaatagaat tagaataatt tgataatatt tgttaaaaga
    57181 gcatttagaa tgtgtttaaa gattaagata ttccttttat ggtagcagat agttgaaata
    57241 ataaaactgt tatcatgaaa ggaatatttt tatgtatagg aaatttttaa aaataaaagt
    57301 taaatatgtt taagaacatc ttaaagtgaa agaatcattg ttagaaatat gtagacaata
    57361 tagtatttat aacgtatcat attaacaagt ttacacttgg attatgaaat aaaaagagta
    57421 attctaaagg ttgtaaatac tatgctgact ttgatacttc aaagtttagg tgattttgta
    57481 attgttaata gaaatacgtt taatgagcat aaagaattta tctaataata ggagaatata
    57541 atgtatacaa ttggacaagt atctaaattt ttaggaatat ctagagatac actaaaattt
    57601 tatgaagaca aaggattagt aaatcctaag aaaaatgatg aaaatggata tagaatatat
    57661 aatcaggttg atatctatga tattgcaaca ataaactttt atagagaaat tgatatagaa
    57721 attaaaaaga ttcaagaaat aagaaaaagt aaaagtataa acaatttaga actcttacta
    57781 gaagagaagg aacaaatcat actaaaagag atagaatata aaaagcttct cttaaaaaag
    57841 gttcagttag tcaaagaaga ttgtgacaaa atcaaaacat attttggaaa atacacaata
    57901 aaagaaatga agcctttgga agtaaaaggt aaaataaaac atgttactaa ctatgaggaa
    57961 tatgaagcct taaaagagaa tacaaacaac ttaaaaaaag cagttacatt aactgattta
    58021 agaagagtaa taaattttaa tgaagaaggt ataatagaag aaaaatttat aattgtaagg
    58081 gaagtagatg actacaacaa aatcatagaa ggtgaagttc tatctcatcc caattgtatt
    58141 tatactatta ttgaagatgg cagatggtca actggaggag aaaatattga taataaagtg
    58201 gaagacagat taagagaaat agcaatagaa aatgaatgtg aattacttgg aatagtctat
    58261 gttaatatat tgcttactac ttatgaagaa gggattgagc gtatattttt agagatttat
    58321 gcacctataa aataatataa aagcattgac ctgggactta ctcataggtt taaactcatg
    58381 atataagcag ttataactta tatagcaatt aaatattaat ttgaaatgag gattacttat
    58441 gagaacagag aaatcattaa aaaggcctat agccagtttt attattctaa caaatataat
    58501 ttttttacca ctttttttat tggtagtagt gactataatg ttaaaacttc caacagtgat
    58561 atctgacatt gcgttgtgta tatcagcgtg gtcatccact tttgcattta tgatattatt
    58621 taaaaaaatt tatccaggta agaaattttt agtacatgta aaagatagat ttagaaataa
    58681 acttaaattt tcaacagtat ctataataat tagtatacaa gtcctaatag ctgtagtagt
    58741 tatatttata ttagcatcta aaaatcatgg aataatgcct aactttacag tttcatcatg
    58801 gggagcattt atatatttat ttttaaaaaa tttatttgca ggatcattag gtgaggaatt
    58861 aggttggaga ggatttgttc aaaatcatct tcagaaaaga cattctcctt taaaagcatc
    58921 cataacagta ggtttttggt gggggatgtg gcatttacca atatggttta caacaggatt
    58981 caaaggactt gatttaataa aatatattat attttttatg attgcaatta tatcaatcag
    59041 tattataatg acaacttttt ataatctaaa taaaactttg ataataccta ttgcaataca
    59101 tcaactattt aattttttaa tagggataat taatgaagat ttaatagagc ttataaatta
    59161 ctatgcaatg ttatatttaa tatttgcaat tgcattaata gttataaatc caggaaatgt
    59221 attatataaa aatattagag agtaatatat atctttatgg taagatataa agatattatt
    59281 agaagaacat ccaaggagga ataaacatgg ttttactgat tgttgatgca caaaagttaa
    59341 taacaaacga gaggttatat aaatttaatg aatttgtagt aaatgtagaa aatttaattg
    59401 atacagctag aaaaaataat atagaagtaa tatatgtacg tcatgatgat ggagttgaaa
    59461 atgaattgac taaaggtaaa aatggctttg aaatatacga aaaatttaaa ccatgtaatg
    59521 gagaaaaaat atttgataaa aaagtaaata gtgcttttaa agaaactggt ctattagaat
    59581 acctaacaaa taatggtgaa aaagatatta ttattgctgg tctccaaaca gattattgta
    59641 ttgatgccac tataaaatgt ggatttgaac atggatttaa tataatagtt ccagcttatt
    59701 caaatacaac tgttgacaat ttttttatgt cagcagaaca atcatataaa tactacaatg
    59761 aatttatatg gaatgaaaga tatgcgaagt gtatttcatt agaggaaaca cttagaaaaa
    59821 tgaaataaaa atagagtatg aattgtatat gtacataagt tgatttcata aaaaaggatg
    59881 ttaaattcca agttaaaaat tagattaaat atattatatt atagataagg cacatcaatt
    59941 ttattttaaa ttaatgtgct ttttaattgt agtaatttat ttataatcaa tatgattttt
    60001 attatttaaa tcaatttttc ttgagtttct ttgtctaaag aaactttttt tatttataaa
    60061 atctacagtt atattatagt atctatttta gatgagttta atttttgtat caatctaaaa
    60121 caaaagttat acttaaatga aattgaaaac gataaaattc tcaaataaaa taagtattgt
    60181 ggaggtgatg aaagaatcca atgataatat gaagactaat cttaataaga aagtaggggt
    60241 taatggtagt ggacaaagaa attgtatcaa ttctccagat tttattaaat agcacattga
    60301 ttacaactaa tggattacaa gaggagtcta attcatcaaa gagacaaatt acttatagaa
    60361 taaataaaat caatgacatg cttaaagtaa aaaatgtacc acttatatgt ttaagagccg
    60421 acaaagatat tatcgttaga aaagaaacaa aaaaagcaat taaagaaatt ttagaaaaaa
    60481 actattctaa gaatacttat tattttagta agacagaaag acttttatat atgtatttaa
    60541 tgctttttat taacatggag gatatttcaa ttaatcattt tataaattct ataaaagtaa
    60601 gtaggtctac tgtaaatctt gatttcaagg atttgatacc agagcttgaa aagaagaaca
    60661 ttaaagttaa gaacaatcgt ataaatggat attacatagt tggcaatgag atggaaatta
    60721 ggagagtact tattaaaaac attatagaaa ctttgtctaa tgagaaaagt tcaagagtat
    60781 ttgatatttt tattaaagaa tataatttag atagttttga agaggctaaa aaaattatat
    60841 taaagctaat aaaaaaatat gaaattactt ttgttgaaga tagattaata gaatttatat
    60901 atatatttat ctttctaaaa gcaaggatgt attcaactag aatagttact caggaaaatg
    60961 tagatattcc taatatttca gttatgagtt caatgaagga gtataaattt gctaaggaat
    61021 tattagaagt atatgggagt gaagataaga taaagcctca caatataatg tatattagtg
    61081 cttggatttt aggtatatca gtaggaaatt atgaagaaga tacagaagat aaggatgtaa
    61141 tttcaaaaat tgtaaataaa atgatgacaa agtttggata tttaagcgga gtttactata
    61201 taagccaaga aaaaatattt aaacaattat attctcattt tagacctgcc tactatagac
    61261 ttttatttaa attacctatc tataatccga tttgtgaaaa agtaaaagaa gaatataaat
    61321 tagtttatag aattgtaagt aatgcaatga aagagttttg cggattattt ggagaagaaa
    61381 ttcaggaaga agagttagca tatcttacaa tgcactttgc aacacttttt tcaaataaaa
    61441 aagaatttga tggttttaga aaaagaatag cattaatagt ttgttcaaat ggcgttggta
    61501 gttcagctat tttacatgca gaacttacaa acttatttcc tgacttacac tttataccaa
    61561 tgtcggaatc agttggatta gaaaatataa gtgaacctgt agatattgta tttactacta
    61621 attataacgc agagggttta aaaacagatg taccagtaat taaagtaagc cctgttatga
    61681 ccacaaaaga aaaatataag attacacgtg aagtgtatat tcaattaggt gatatttttt
    61741 taagacaacc taaaatagat gaggttatgg atataataaa aaaatatgca aatgtaacct
    61801 ctgaaagtat tctttcaagt gagctattag cttattttac acagatagag aattttacat
    61861 ctaaggaagg agaggggcct atgctaagtg agattactaa tgaaacacta gtaaaaataa
    61921 aggtaaaagc taagaattgg gaggaagcta ttagacagtc agcttctgta ttagttgaaa
    61981 ataacaaagt aactgaaggg tatgtagatg ctatgattaa ctcagcaaaa gcatctggac
    62041 catacatagt aattacaaaa catgttgcac ttccacatgc tagaccagaa gctgggtcaa
    62101 aagagattgc aataggcatt gctactttag atagtcctat tgagtttggg aataacgaaa
    62161 acgaccctgt aaaatatgta ttttgtctaa gtgcaataga caataatagc catttacgtg
    62221 ctatgtctga gctagttgaa ctattggaag aagatgagtt ttttaaggtt ttagatagtg
    62281 ctaaagaagc taaagaaatt attgatttta taaaaacaca cgaattataa aggaggattt
    62341 aattatgtat aaaattttaa tcgcatgtag agcaggagtt ggctcaagtt taatgttaaa
    62401 aataaagact caacaaatta ttaaggaaaa taactttcca attgaagtag agcatggttc
    62461 attggattca ctaaatggat tcaatggaga tgctgtagaa acattaattg atgttgctga
    62521 agaattaaaa aataaaaatt tgaagtttga tataattggg attcacaata ttgttgaccg
    62581 taatgaaata aagacagcac tagaaaaatt ccttgcttca aaagagggat aaatttaaga
    62641 tgataaggag gaatatttat ggagtttatt attagtttgc tgagtacacc tgctgttttg
    62701 cttggcgtag ttgcatgtat aggattgatt cttcaaaaga aatcagctgt tgaagtattt
    62761 acaggctctt caaaaacact tatcggtttt ttgatatttg gtattggtgc ctctgctatg
    62821 acaggagcac ttcaaaattt caataaactg ttccaacatg gctttggaat tactggtgtt
    62881 atagcttcac cagaagcagc tacagcactt gcacaaggta catatggttt tgcagtttca
    62941 tgtacattaa ttcttggatt catattaaat ttagtatttg cacgtattac aaagtttaag
    63001 aatattttct ttacaacagg tcatagtttg ttcttttctt gtgtattagt tttaattatg
    63061 aaagcacatg gatttgataa tacaatcact attttaatag gtggaactat cttagggttt
    63121 atgtctgctg cactacctca attctgtcaa ccatttatgc gtgaattaac aggtggcgac
    63181 gaacaagcta ttggtcactt taacatgatt ggttatggtt tatcaggtta tattgggcgt
    63241 ttattttcaa aacataaaga tgatacaaca gagactatag aatttcctaa gtggttatca
    63301 atattcagag acttcttaat gggtctatcc atagttatgt taatcttatt ttatattgca
    63361 acattaaaag ctggtcaagc atttactcaa gaaattgctg gttcaacaca ttggttggtt
    63421 tttccgctta tagaggcatt tacatttgtg gcaggtatgt caatattgat gtcaggtgtt
    63481 cgtatgttct tagctgaaat aactgcagca tttgtaatca tttcagaaaa gtatattcca
    63541 ggttcacgtc ctgcgctaga tgttccaaca gtatttccat atgcaccaaa tgcagttatt
    63601 attgggttta tatcagcata tgctgctggt ctattagcaa ttgctattat ggcatcattt
    63661 cctagtatat ttcctgtagt aattattcca gctgctcaca tatgtttctt ctcaggaggt
    63721 acagctgcaa tatttggcaa tacttcagga ggatggagag gggctattgc tgggtcattt
    63781 gttgtggggt tattacttgc atttttacca gttatactat atccagttta tggcactctt
    63841 ggtatagaag gagcaacttt ccctaatatt gattacaatg tagttggttc gatattacat
    63901 aatattttac aatttataaa acctatttaa actaaattat ataaaagtat agtcatagtt
    63961 actatgattt caaggaggat acatcttatg gaaaatacat tatctgaatt tttagataat
    64021 atatctaatg aattgtcaga atttattgcc tcaatagatg agacatctat aaataaagca
    64081 tgcgaattaa ttcttgaagc tgaaaaaaat cacggacgtg tacatgtgac tggtattggc
    64141 aaaccaggac atgtatcggg atatatttca tcattgcttt catctactgg aacgtcagca
    64201 tatatattgc atggtacaga agcagtacat gggtcaagtg gtcaagtagt tgaaggagat
    64261 gttgttattg caatatcaaa tagtggtgaa actcaagagt taaaagcaac tcttaagact
    64321 ctaaaagtaa atggagcaaa gataattggt gtaagtggta atgagagttc atttttaaaa
    64381 aatatttctg atatattcct gtttgcaggt gttaaacagg aaggagattg tcttaataaa
    64441 gctcctcgtg cttcaatttt agctgaaaca ataatattac aatcattaag tgttgtatta
    64501 caatatgcta aaggtcttaa tacacagcag tatttgaagt ggcatccagc aggaagtctt
    64561 ggaaagtcta ttagagaggg aatataattt tatgaaatat aaagggatta tatgtgcaat
    64621 gataacacca tttgatgaaa atcaaaatat taattcacaa gcaacatgtc aattaattga
    64681 ttatttgatt gaaaagggaa tttatggatt atttattttg ggcactaatg gtgaatgtca
    64741 tgtattaaca gatgatgaaa aagttgaatt tgcaaagatt gttattaatc atacaaataa
    64801 tcgtgtacct gtttttgttg gaacaggggg taattcaact cgtgaagttg tagatttatc
    64861 taagagaatg gaagcgattg gagcaagtgc attatctatt attacaccat actttgttac
    64921 accaacacaa caggaattaa tcttacatta caaaactatt gctaattcag ttaatttacc
    64981 tattataatg tataatatgc caagtaagac tggaattaat attgaaccag agtcagtacg
    65041 tgaattatca aagataaaga atattgttgg aattaaggat agtagtggta aacttgacaa
    65101 catgaaagct tatattgaag caacgaagaa tgagaatttt agtgtgtttt caggctcaga
    65161 ttcacttatt ctggatagtc taaaagctgg tagtcaagga gctgttgcag caacaacaaa
    65221 cttcctcaca gagattggta tctctatcta tgaaaacttt atgaaagggg atttggaaga
    65281 agctcaaaaa gctcaaagta gtatagaaga acttcgacgt atactgaaac ttggaacaat
    65341 tccatctgtt atgaagaaaa ctattgtctt gaatggaatt aatgttggaa ctgcacgact
    65401 tcctgtaact gaaccaactg gggaagtact tgaagaaatt aaacgagtag ttgaaaatta
    65461 taggacaata cttaataaaa gtagtgagaa tagataatat aaatagggaa attacactgg
    65521 tatataatta atatatatat tataaaacat gactaaaatt aatgaataag taaagtggtt
    65581 tgatgagtat agaggtgata atatgaaaaa gatgaatata accaaaagaa tgtcagaatg
    65641 tggggctctt gcaattgtaa gagaagaaaa tcttaaccgt gcatgtgaaa ttgctgaagg
    65701 atgtataaaa ggtggtataa cagttataga aatgagttat accctaaata atgctggaga
    65761 aataattcaa gggcttaata aaaagtatgg tgaaacactt tgtgtgggag caggaacagt
    65821 tttggatagt gaaacagctc gtcatgctat attacatgga gctcaattta ttattgcacc
    65881 aaattacaat gaaggtgtag cgaagatttg caatagatat cagattcctt atgctccagg
    65941 atgtacatca ttgactgagg cagtagacgc actaagttta ggagcaactt ttataaaagc
    66001 tttcccaata tcagatttct atggacctaa actagtaaag gtatttaaga caccaatacc
    66061 tgatatgcca gttttagcaa gtggagggat taatattgaa aacctacata tatggttaga
    66121 aaatggagtt gatgtatgtg gatttggtgg tttattaact aaaggttctg ttgaagatat
    66181 tgctaaaaat gctaaaaaga ttcgtgaaat cattaaaaat ataagaaaaa tttaacatag
    66241 ggctgtatca tagtatctta taattactat gatacagcct ttttaatatt attcaaatta
    66301 aaaacagttt acatttctat tatattacat ataatttcag taattttatc ttaatttttc
    66361 tatctggaaa aaaatgattt aaaacttaag ttatgatata atttcattaa aagaaggcga
    66421 tttttagtaa atatgagaaa ataatgtgtt tttaggggaa aagttaaata cagatttaag
    66481 tgaacaagaa tcgataatta agatattaaa tggtgaatag ggcatcaaaa aaattactaa
    66541 attaaaagtt ttagagggag aatcttagca agtgtgtgtg aaaattcaat ttcaaacaaa
    66601 aaataattgt aaatgaaatc aatttataca cgttgaagat tcacttttat cattatatta
    66661 aaaagcagag tgaattaaaa gtgagtctaa agataggagg ataattaaaa caatgaaaga
    66721 agacattagg ttacatcgaa tgtgtaaaaa agaacaagca acaaagaatg aagttatatc
    66781 agaggatatt ctaaaatcta tgagtattgg ggtcagtaaa cattttttag atgattcatt
    66841 tacaataata tggggaaata catcattcta tcaattatta ggatatacag aagaagaatt
    66901 tttagttaaa ttttctagtt taaaagatta ttatgaacag aatctttatc attttgaatc
    66961 tatgaaaaat cattttttag aggcttatca tcatggcgaa aagagtatag aatatcaaat
    67021 ttgcatttca gcaaataatg gagaccctgt ttgggtaata atgactggta tattaattga
    67081 atcacaagat aatgagaaat caatggtcta tatattgtat tcaaaaatta atgagttaaa
    67141 aataaagcaa gaagaactat ctgatatgga aaaagagagt acagagaatt ttaaatggat
    67201 gatgtcagag tatgctggga atgtttatat tagcgatatg gatacatatg aattactata
    67261 cttaaataag cactcatgca atactttaca ggcatcagca aatgaactta ttggaagaaa
    67321 atgttatgag gtaattcaag gtagaacttc gccatgtccg ttttgtacaa attcgtattt
    67381 aaaaaaagat gacatatatg aatgggaatt ttataataaa aaactgaaac gaacatttat
    67441 aattaaagac cgtatgttga attggcaagg gcgaagagtt cgtattgaat tatcttatga
    67501 tatgtatagt gctgaatata aattagcaaa aaaagatcag gaaagagaat caattttgaa
    67561 aactattcca gcaggaatgg ttagattaga tgcaagagat tatcttacta tactttggtg
    67621 taatgatata tttttgaata tgattgaata tacaaaggaa cagtttgcag aggaacttaa
    67681 taatcaatgt ggatatttat tttctgaaga ttataaacgt agtaagaaac tggcacaaga
    67741 tttgaaggag tctggggata atgttgtatt tgaagcaaaa atatatacac gttcaaggga
    67801 agaacgtata tggactgtta cattgtgtta tatcagtggg gaagacagtt gggatggaat
    67861 accatctttt tatagtatag gtattgacat aacaaaggaa agaaaacaga ttgagaaatt
    67921 acagcatata tcagagaaag atgcattaac aggaatttat aatcgtgctg agactgaaag
    67981 gcagattaag aaatattttg aaaaaaattt aaatgttatg ggtgcactgt ttatgattga
    68041 tacagataat tttaaacaga ttaatgatac agaagggcat atgattggag atatagtact
    68101 tactgagatg gcatcaggta tgaaaaaaat aatgcgtgac agtgatgttg ttggaagaat
    68161 aggtggagat gagtttacaa tttttatgaa gaatatttcc tcagttaaag atgcagaaaa
    68221 gaaagcagaa gaactattgt atatgttccg tcatctattt cagaaagaaa aaagttttct
    68281 aaaagtaact tgtagcatag gaatagctat atatccaaag gatggtacta cattcaagga
    68341 aatatatgca agagctgata aagccctgta tcaagcaaaa aatatgggaa aaaataatta
    68401 tgtaatctac aaccaagatt attttaaaga attagaagaa tttgattgtt cttctcttgg
    68461 tacagttatt gattcagaaa aacaatacgc tgaatatcct gataatctta cacgttatat
    68521 attccgtatg ctttatcaga ctgatgatat agaccaggcg attaatatga tacttgaggt
    68581 tgttgggaaa cagtttgatg taagtcgtgt ttatattttt gaaaatacag aagatggtag
    68641 atatacttct aatacttatg aatggtgtaa tgaaggaatc tcttctcaaa tggcttattt
    68701 gcaaaacagc aattatcaag actatgagga ttatgaaaag ctttttgagg atgaattagt
    68761 tttttattgt cgagatatcc atacattaag tcctaaacta gaagaattgt tttctagtca
    68821 aggtatccac tctacacttc aatgtgcata taaagaagat agagttttca gtggatttgt
    68881 tggatttgat gaatgcacag gactacgtct atggtcacaa gaggaaataa gtacattatc
    68941 attgatttct caaattatat caatgttttt acaacgtaaa aaaaataata aacttaatca
    69001 acagattcaa caataccaga atattttaga taatattgac cagtgtattt gtgtgattaa
    69061 taaagaaaat aattttttat tatatgtaaa taaaaaattt aaaaatacat attctaaatt
    69121 ccaaattgga caaccttatt atcttgattc tatagatatt cataagatat ccattatatg
    69181 gaataaaaaa gaagcatacc tatgtactag cacgatttaa tggtaaagta aagtttatat
    69241 tggacttaaa ttaaatttcg ttttaaataa gatattattt tagttgctta ctgaaaagac
    69301 tagaatctat attaatgaat tatactaatt ttataccact attaaaatat tgtttgctaa
    69361 aaataaaaaa tagccttaaa acagttgatt ataaaaaatt aactgcttta aggctatttt
    69421 tatctttgtg acgaaataga cacttgccat ttagaatgtg acaatatagt agttgtttag
    69481 aaaaggcaca aagcattata ctttaactaa agtaaaatgt attttgcttt tagaataaaa
    69541 acaattagga gggagctata attgaaaaag ataatatatg tattatttac aattgaacta
    69601 ttaatagtat ctttattagg tctaaatata gttaaagata atgaaattaa taatatttta
    69661 tataacgaga caacaagtat atctgtaatg tttaaagatt ataaaaagtt aaataaaaat
    69721 tatagtaagt ggattaaaga tattgcagat gaaaataatg tgactatatc aaagtatgtt
    69781 tttaataata atgaaaaatt atctatatat acgactgata caagtttgaa taacaatata
    69841 aagttaaaat caggaaaatt tcctaatact aattcaaatg aatttattag taatataaac
    69901 actaataata gtaatcaagt aggtaaattc tcaactatga gtaaagacat atcaatttta
    69961 attagggatt ttggtaaaat aagtgaagtt ggagaatcag gaatcttata tatttcaact
    70021 caaaatgaag atacaataaa taaaatatta agagaactaa atgtagacag aagtattttt
    70081 gtagcaagat tacatgatag atatgttaac tcaaatttat acttaaatcc ttcaataatt
    70141 agagatttaa tactaattat cctttgtttc ttggctacaa taatacatta ttcaattagt
    70201 gtgagtagag aggcttctat tttaagatta aatggatact ctaagctaga tataattgct
    70261 agagttataa aaaatatact tagaattatg attttatcat ctgtcacagc attattaata
    70321 tatataatct atattttaaa attaaatata ggtgttagag catgcttata ctttgctatg
    70381 ttttcgatta tatgtatttt gataaatatt ttgatatcta tattaatagt tggttttaat
    70441 agtagaagtt ctaaatatgt gctatctcta aatggaaaaa aatcttatgg ttttgtaaat
    70501 ataatgcatt tcacattgaa aattgtattt gtatcatttc ttatattatc cataaataac
    70561 tgtattttaa attataatat gctacaaact cagttaggaa atctatctga gtgggataaa
    70621 gcaaaaaatg tttataatct tactcttaaa gatacaggcg aacaatcttt aggaaaggaa
    70681 gaagtaatta aaaatgccaa gattaaaggt ttctataaaa atttggtaga agaaaaagat
    70741 gctttcttaa tagattcaac taattttgaa aaacttgaag atggaagtta catgtatgaa
    70801 ataaattcaa agggtaaaaa cccagaagta agtcaatatg gtaaaaatat aaaaataaat
    70861 aaaaactatc ttaaagttaa ccctatttac tcaaatggca aagaaatatt taatctaatc
    70921 gattatgacg ataagactat aaatttatta gttcctaaaa agttacaagt acatgaaaat
    70981 gagattaaaa aagagtttag agaattattt tattttgaaa aaatagaagt agaaaatatg
    71041 tacaataaag agttaaatag agcgttaaac aaaacaaaga agtcagattt aaatgttaat
    71101 ataatatatg tagataataa tcaaagctat tttacttata actcccttgt tatggatgac
    71161 aataggaatc tcattgatga cccaatagca atagttgaca tagataatat tgatgattct
    71221 ttttatcttt cttatatatc tagatgtgta tattttaatt ctaagaaatt agatgccctt
    71281 gcagatataa gtagcattat tgaagctcaa ggtgtagaag cgcatatcca aagtttacat
    71341 gctgtttata atgagtatgg tttagaaata aataaactag aaaaatattt gaatagtgaa
    71401 atttttacta taataataat agcaatatca aacttaatga ttacctacaa tatagtagct
    71461 agctactatg aaagaaataa atataagtta tatattaaaa aaatatttgg ttattcaact
    71521 acagctagaa gtatgttgtt aatagtctca ttaatattaa caaacattat tccaataggc
    71581 attatatcaa caagagtaga tttaagtaat aatattatct tatttggact tctaatatta
    71641 gttatagaag taattgtatc tattgtatta gacaagatta tctcaaatag ttcatttaat
    71701 aaaattataa aaggagaaca ttaaaaagat gatttcatta ataaatatat ctaaaaaatt
    71761 taaagataaa tctataatag acaaatttaa cctagaaatt tctaagggcg agtttgtagc
    71821 gataacagga aatagtggtt caggtaagac aactttactt aatataatgg gattattaga
    71881 aaaacctaat tctggtgata ttataataaa taatataaaa aatccaaata gtaaacagat
    71941 aagaatttta caaagggatt tttatggcta tctatttcaa aattatgctt taattgagaa
    72001 tgaaaatgtt gaaaataact tgaaaattgc tttaaagtat caaaaaaata tcaaccataa
    72061 taaaaaaata aattacgcac ttgagtctgt aggtcttaga aaatacaata aaaaaaagat
    72121 atacgaattg agtggaggag aacaacaaag ggtagcatta gcaagagtaa tattaaaaga
    72181 atgtgaagta atatttgcag atgaacctac aggtaattta gataaaaaaa atagagacat
    72241 agtatttgat atacttaaaa gtctaaataa gaatggtaaa actatcgtat ttgtaactca
    72301 tgatttagag ttatcggagc aggcagatag agttataaaa ttgtaataat atcaactata
    72361 ataaatataa gaaagagatt acagctaaat caagtttaat aataatacga atagaattta
    72421 aacattaagt aaattagtag tttgtaaata taagtataat atgatatcat aaaggctcaa
    72481 aagaaatttt atataataag aaatctaaaa ataacaaatg gaggacatat aaagatggaa
    72541 aatttaccaa attgcccgaa atgtaattca gaatatactt atgaagatgg aactctttta
    72601 gtttgtccag aatgctctca tgagtgggca ttaggattgg gagctgaaga agattcaaat
    72661 attatcaaag atgtaaatgg aaatgtatta aatgatggag attctgttac agtaattaga
    72721 gaccttaaag taaaaggaag ttcatcatct ataaagattg gaacaaaagt gaaaaatatc
    72781 cgtttaatcc atgactcatc agatggacat gatatagaat gtaagataga tggttttgga
    72841 gctatgaagc taaagtcttc tgttgttaaa aaagcgtaat attataaata agctgtagtg
    72901 tttattgttt ttcagtacag tataaaacca taagaatcta ttaagtaata aaagtttgtt
    72961 tatttatctt tatattttct tatggtttta ttaaatataa attttattga acaccaaaat
    73021 attctctcct ctacaaataa gccaatctta tttaaattaa tatactttgt actatttata
    73081 ctgaaattgt aaatttaaat gctatgttat ttaggtttgt atagttaatt tatatatttc
    73141 tgattttata aattgtattt attattatat cttgattcta aaatcattaa aaatttcaac
    73201 ttctataaag atttacaatt tatcaaatac attatgagta tataaacaat ttattattac
    73261 agtgctacat ttaaaataag tcttagtata aaggtattgt tacaagtata aagaaactta
    73321 tgtatgctat tggaataaat aataccttaa attataataa agaataagaa ctgttaaata
    73381 agggacttga ttatcattta gttatagata atataatatt aaaaataaag tttaagagga
    73441 gaaaaaatat gatagatata cataaaaata tatatgataa taagttattt gaggagctaa
    73501 agattgactg taagaagtgc tttggacttt gctgtgtagc tctttatttt tctgcttcag
    73561 atggatttcc tatcgataag gaatcaggaa aaccctgtat taatttacaa ccagatttta
    73621 aatgttctgt acataatagt cttatgaagc gaggttttaa agggtgtact gcatatgatt
    73681 gttttggttc aggtcaaaaa gtagcacaag taacatataa ggggatagac tggatgcaat
    73741 catcagaact aacaaatcaa atgtctgaag tgtttttaat tatgagacaa ttacatgaaa
    73801 tgttatggta tcttaaagaa gcatctgtat taaatatatc agatacaatc aaatcaaaaa
    73861 ttgatttaat aattgaagaa actgaaaaga taactaatat gagcccagaa cagataatta
    73921 atttggatat catatcacat agaataaagg ttaatttatt attatcacaa gcgagtgagt
    73981 ctgtgatggg aaaggttaaa tcatttatca agacttctac tcttaaaaac atgaaaaaat
    74041 taagtaaaaa tatagattta ataggagcag accttagaaa aataaatcta ataggagcag
    74101 atttaagagg tagatttcta atagcagcaa atttaagaaa tacagatttg agtggggcaa
    74161 atttaatagg agcagactta agagattgtg atattagagg tgctaatctt gaaaatagta
    74221 tatttttaac acaattacaa gtaaatactg caaaaggaga ttctagtacg aagttaccag
    74281 cttcactaat acgccctaaa tactgggaaa aataattaaa ttaatacata attttacaaa
    74341 acatgaactt ttttgacttt aattcatatt atacattaga gattctttac aagaatttct
    74401 taatataata tagggagaga tataaaaatg agttatcaaa attataaatg tgaaagagat
    74461 tatgtgtatg atgattataa atacaataag tgcaacaagt gctataatga ttatgaggaa
    74521 atgacacatg ttcatgaata ttcagaaagt gttaagttag cagaagaatg tgaggataga
    74581 cataaccacc gtgcagcagg ggttactggt gaagctatac caataaatgg aggtacaaat
    74641 catgttcata aaataaatga taatgtagat ttccttgacc atttccataa gatatgtgtt
    74701 acaacagggc cagcaattag aatacctgga actgataaac acattcactt aatatgtgga
    74761 gaaactactg ttaatgatgg tcattgtcat aaattccttt ttactactca aatagaagca
    74821 cctttagtat aagctgatgt gaattattgt agtgaatttg ctagattata gtataataat
    74881 atataataga taatatttaa acttaatgag gactatgata tttaaccttc gtagtccttt
    74941 ctaagttttg tataaaaaag tgttatgcaa ttaaaagtga tatagggagg aaatttttat
    75001 gaaatctgga ataattcttg aaatgaaaca aataaattca acagaatatg acgaaatgtt
    75061 gcaagtctgg gaatcatcag taagagcaac gcatgatttt ttaacagaaa aagatattga
    75121 atctttgata ccattagttg agattggact taaagaagta gaaaatatag tttgtataaa
    75181 agataatgat ataataaagg gctttatagg aatagataaa gataaaattg agatgctctt
    75241 tatagaagat aaatatagag gaaatggtat tggtaaaaaa ttaataaaat atgctataga
    75301 taaatacaat gtaaaatatg ttgatgtaaa tgagcagaat aaaaaagctg taggatttta
    75361 tattcactta ggatttaaag tgtttgatag gtctgaaata gatggacaag gtaacccatt
    75421 tccaatacta catatgaaat taatttaaag ttatacttct catttattcg caaaaatatt
    75481 tacttaaatt tttatacaaa taaaagtcgt gacagtctta ggacacgact tttttactac
    75541 actattaaat tgaaatttat ctgttctata ttatgattat tagatgtcgt ttttttattt
    75601 taactatgta cttaaatacc aagtataccc atacctatca agtacttcag cagcgccatc
    75661 attttgatgt ggtggtgggt gtggtaaaaa ttcttgtaca agtgtaccac cttcggcaag
    75721 ttttacagat atttcttcta tcgcttctcg agatggtaga acaacacaaa tcgccatgcc
    75781 agaaattaca acaggcttgt ctgtatccgc acccattata caaccttcgt attttgtgaa
    75841 agtaacactt gcgtgcataa taggattgtt tggattgctg tctaatcgcg caaatatagt
    75901 ttttcctcct ccgaaagcct cagcataaaa attaaatgct ttttcacaag taccattaaa
    75961 tattaaatat ggagttagca tgaccaatat atcctccttg atatagaata atttatagtt
    76021 gcacctgata atctaaatta tgatttagta aattgtatca tagggaaacc ttgaagtata
    76081 taatttttta ttattatatt atacaaattt attaatttaa aaaaatgtta tatgtacgga
    76141 aggtttacag gataaaatat aataaaaaga ttaaggtgac attataaaaa atgtatattg
    76201 acattgacgc tacgtaattg tatatacttt gtcttaaagg agatggtaaa tatgaatatt
    76261 atagaaattc gctcagataa aatatacaag aagataatgg atgcaccaat aaacaaaaaa
    76321 gaagatatat acagatatga attgatgaag ccttttgaat ttaagtggaa gtgtatgaat
    76381 gttccaatag ttgctagaca gaaaggtgga tatgatgtaa ttatagcaag tgaaatgtta
    76441 ggggttttat cgcctaagga tattgatgaa aaacaaaaaa agaatataaa tgtgttatct
    76501 gctgataaaa tttgggccac ttgtaaagaa accatagaaa actctataaa tgcttttata
    76561 aaagaagggt atgatttaaa tattaaggac tataaatatt caatattatt ggcgaatcca
    76621 aatagtcctt atacaatatt aagtgatgga tactggggtg atggtgggat tcctggatat
    76681 atatttctat cattggttcc taatgaatat actatcaata gattaccagt attaatagca
    76741 catgaatgta atcacaatat tagatttcag tttatagagt ggaataataa tataacatta
    76801 gaagaaatga tgataaatga aggtcttgca gaaaattttg caacatggat gtttggagag
    76861 gaaatgttag gaccttgggt cagtagaaca gatatcgaaa cattaaatac ttatataaag
    76921 ccaataataa aaagtgcttt aaaagaaact ggatttcaaa atataacatc ttatctttat
    76981 ggtgatgata tagctaaaat gcaaggatat tttccagtag ggttgcctta ttgtgcagga
    77041 tatgcttgtg gatattatat gattaagtat tatttagaaa agacaaataa atcaataatc
    77101 gaagcgactt tattgcctta tagtgagata atcgaagcag taaaagagtt ttgggaataa
    77161 attttataaa ttgcataatt tgaaataaat tatgcaatta ttttattttt aagaaaaaat
    77221 aaattgacaa taatttataa gaaatataca ataatatata taaagaaata tttcaatatt
    77281 taaaagtttt aagatttcat atctagagta cctaacatta catgttagtt tcttgttact
    77341 tatctaatta ctttatattt cgtagttata tataaaatta ctataaaaaa tgaaatatat
    77401 taaacaatca actaaaaaat gaaatattaa taaaaaaaaa ttcaaattat aaatattaaa
    77461 tgaatataat taaaacaaat atataaattt aagtataaca ctcacatttt aatgtattgt
    77521 gaaatttttg ttgaacttta tgtaccataa cttataaaat ttatgtcatg ttatatttga
    77581 ataagtaata aaattgtaga tgtaaattaa tctacaaaat ttatatgaaa tggagttgat
    77641 gctatgacag aattaatgat tataagtggg ttagtactat tgatttgtat aacttctagc
    77701 aaggtattgt ataaatttgg agtaccaata ttattgattt ttatcttact agggatgtta
    77761 tttgggtctg atgggatggt aggaatctat tttgataact atgaactgac aaaacaatta
    77821 tgttctattg gactaatatt tataatgttt tttggagggt ttggaacaaa ctggaatatg
    77881 gctaaacctg ttgctatacc ttctatatta atgtcttcac tgggtgtaat aattacggct
    77941 ggggttacag gtatgttttg ccacatggta ataggaacta gtttacttga aggtttatta
    78001 attggggcaa ttgcagcttc aacagatgct gcatctgtgt ttgctgtgtt gcgttctcaa
    78061 aaactaaact taaagggttc acttgcatca ttattagaag ttgaaagtgg aagtaatgac
    78121 ccaatagcgt atatgttgac actaattctt ttgacattga tgaataattc tggggtagaa
    78181 cttattgcac caatggtaat aaaacaaata gcttttgggt tagctatagg atttatacta
    78241 gcaaaattat ctgtttatat tttaagacat tcaaacttcg agatagaagg attttatact
    78301 atatttataa cagctattgc aatactttct tatgcattta gcgagtatct tggaggaaat
    78361 ggatatttaa gtgtttacat ttcaggtatt attataggaa atagtaggat acctcttaaa
    78421 aaaagtttgg ttcatttctt tgatggaatt tcatggatta tgcaaataat gttattcttt
    78481 atgttaggat tgttatcttt cccttctaag ttaccaaatg tatttggtat agcaatggcc
    78541 atatctatat tcatgatagt tattgcaaga ccattagcaa catttatagt tctagcaaaa
    78601 tttaaattct caaataaaga aaaattattc atatcgtggg taggtcttag aggtgcggct
    78661 tcagtagttt ttgcaattta tgctgttact caaggagtag ccatagagaa tgacatattc
    78721 catataatat tttttatagc gttgctttca gtaggaatac aaggttcatt gataccaact
    78781 gtagccagaa agttggattt agttgatgat aatacacctg tattaaaaac atttaatgat
    78841 tatgatggag aaattagctc taaacttatc gaagtaaatg ttgatgaggg taataaatgg
    78901 gctaataaga gtataataga ttctaatata ccagacgata tattaatagt tatgataaaa
    78961 agaaaggaac aggttttaat acctaaaggt tcaaccatta taaaaacagg ggatattttg
    79021 gtattgagtg gagatagaat tgaagaatta atacaattat aatttatttt gtattgactt
    79081 taacctaagg ggaaagttta aacttaaatt aatcaaatct aatgcgcagg tgatgagatg
    79141 ttttctatag gaatgttttc taaaataaat aaaataacta caaagacatt aaggtattat
    79201 gaagatatag ggttgttaaa accagaatat gtagatgaat ttacaaaata taggtattat
    79261 acaacagagc aattacctaa attacatcag ataataactt taaaacaaat gggtttatca
    79321 ttagctgaga taaaaaaagc tgtagaaaat cctgaagaag ttgaaaatat tttaatgaat
    79381 aaagaaaaag aaatgttgga tgtaattaaa agtgaagaat ataaaataat taaactacgt
    79441 aattacctta tgaatttgaa aggagaagtc aatatgaatg atgtaattat taagtcttta
    79501 ccaaaagtta aagttgcttc tatgagaaaa gtgttaaagg ggtatgatga actttttaat
    79561 ctatttccaa atgtaatggc tgaagaaatg atgaaaacag ggtgtacatg tgcagttcct
    79621 gattattgtt ttaatatata tcatgatggt gaatatagag agactgatat ggatgttgaa
    79681 atgtgtcaag ctataaatga tttaaaggaa gatacggata tattaaaatt taaagaatta
    79741 gatgcagttg aaaatgcagt ttgtatatta cacaatggtc catattcaac attaggaaaa
    79801 acttacgcag atgcatttaa atggatagag gacaataaat ataaagtggt tggaaatcct
    79861 agagaatctt atatagatgg tatatggaat aaagagagtg aagaagactg gttgacagaa
    79921 gttcagatac cagtgaaacg catgttataa tatgtctaca aagtataaat aagaataaaa
    79981 aaggtggtgt ctcaaagtaa acattttagt ttatgagaca ctctttttca tatgaaatca
    80041 agtatatttt tataattacg attatgaaaa aaggcttatc tatattttta gacagcctct
    80101 tattttttta ttataatagt tttctaaaga tgctctattt ataaattttt attaaagact
    80161 ttataaataa ttg
//
LOCUS       DAGQVA010000008        75437 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.008, whole genome shotgun sequence.
ACCESSION   DAGQVA010000008 DAGQVA010000000
VERSION     DAGQVA010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 75437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75437
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.008"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            46..120
                     /locus_tag="MIV85_000671"
     tRNA            46..120
                     /locus_tag="MIV85_000671"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:78..80,aa:Thr,seq:tgt)
     gene            complement(280..957)
                     /gene="srtB"
                     /locus_tag="MIV85_000672"
     CDS             complement(280..957)
                     /gene="srtB"
                     /locus_tag="MIV85_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBY2960043.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            1089..1423
                     /gene="rnpB"
                     /locus_tag="MIV85_000673"
     ncRNA           1089..1423
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="MIV85_000673"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            1701..4244
                     /locus_tag="MIV85_000674"
     CDS             1701..4244
                     /locus_tag="MIV85_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBY2960044.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            4367..6358
                     /locus_tag="MIV85_000675"
     CDS             4367..6358
                     /locus_tag="MIV85_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960045.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            6348..6668
                     /locus_tag="MIV85_000676"
     CDS             6348..6668
                     /locus_tag="MIV85_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960046.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            6866..7735
                     /gene="galU"
                     /locus_tag="MIV85_000677"
     CDS             6866..7735
                     /gene="galU"
                     /locus_tag="MIV85_000677"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBY2960047.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            7759..8772
                     /gene="galE"
                     /locus_tag="MIV85_000678"
     CDS             7759..8772
                     /gene="galE"
                     /locus_tag="MIV85_000678"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBY2960048.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            8884..10818
                     /locus_tag="MIV85_000679"
     CDS             8884..10818
                     /locus_tag="MIV85_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBY2960049.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            10973..11836
                     /locus_tag="MIV85_000680"
     CDS             10973..11836
                     /locus_tag="MIV85_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBY2960050.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(12044..12925)
                     /locus_tag="MIV85_000681"
     CDS             complement(12044..12925)
                     /locus_tag="MIV85_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2960051.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            13338..14186
                     /locus_tag="MIV85_000682"
     CDS             13338..14186
                     /locus_tag="MIV85_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBY2960052.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14250..16172
                     /locus_tag="MIV85_000683"
     CDS             14250..16172
                     /locus_tag="MIV85_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBY2960053.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            16254..17117
                     /gene="aroE"
                     /locus_tag="MIV85_000684"
     CDS             16254..17117
                     /gene="aroE"
                     /locus_tag="MIV85_000684"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBY2960054.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            17317..18534
                     /locus_tag="MIV85_000685"
     CDS             17317..18534
                     /locus_tag="MIV85_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2960055.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            18770..20635
                     /locus_tag="MIV85_000686"
     CDS             18770..20635
                     /locus_tag="MIV85_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBY2960056.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(20813..22177)
                     /locus_tag="MIV85_000687"
     CDS             complement(20813..22177)
                     /locus_tag="MIV85_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2960057.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(22356..23699)
                     /locus_tag="MIV85_000688"
     CDS             complement(22356..23699)
                     /locus_tag="MIV85_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBY2960058.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(23772..23873)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24202..24855
                     /locus_tag="MIV85_000689"
     CDS             24202..24855
                     /locus_tag="MIV85_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBY2960059.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            24996..26267
                     /gene="brnQ"
                     /locus_tag="MIV85_000690"
     CDS             24996..26267
                     /gene="brnQ"
                     /locus_tag="MIV85_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBY2960060.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            26469..27656
                     /locus_tag="MIV85_000691"
     CDS             26469..27656
                     /locus_tag="MIV85_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBY2960061.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(27886..29910)
                     /locus_tag="MIV85_000692"
     CDS             complement(27886..29910)
                     /locus_tag="MIV85_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2960062.1"
                     /translation="MDKKKLILITHDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            30300..30968
                     /locus_tag="MIV85_000693"
     CDS             30300..30968
                     /locus_tag="MIV85_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960063.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            30970..31455
                     /locus_tag="MIV85_000694"
     CDS             30970..31455
                     /locus_tag="MIV85_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBY2960064.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            31516..32637
                     /locus_tag="MIV85_000695"
     CDS             31516..32637
                     /locus_tag="MIV85_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBY2960065.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            32918..34108
                     /locus_tag="MIV85_000696"
     CDS             32918..34108
                     /locus_tag="MIV85_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2960066.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    34242..34497
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            34556..35557
                     /locus_tag="MIV85_000697"
     CDS             34556..35557
                     /locus_tag="MIV85_000697"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBY2960067.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            35661..36050
                     /locus_tag="MIV85_000698"
     CDS             35661..36050
                     /locus_tag="MIV85_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBY2960068.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            36211..37419
                     /locus_tag="MIV85_000699"
     CDS             36211..37419
                     /locus_tag="MIV85_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBY2960069.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(37505..38581)
                     /locus_tag="MIV85_000700"
     CDS             complement(37505..38581)
                     /locus_tag="MIV85_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBY2960070.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            38810..39337
                     /gene="hpt"
                     /locus_tag="MIV85_000701"
     CDS             38810..39337
                     /gene="hpt"
                     /locus_tag="MIV85_000701"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBY2960071.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            39426..40358
                     /locus_tag="MIV85_000702"
     CDS             39426..40358
                     /locus_tag="MIV85_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBY2960072.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            40420..41646
                     /locus_tag="MIV85_000703"
     CDS             40420..41646
                     /locus_tag="MIV85_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBY2960073.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            41730..41951
                     /locus_tag="MIV85_000704"
     CDS             41730..41951
                     /locus_tag="MIV85_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBY2960074.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            42140..42310
                     /locus_tag="MIV85_000705"
     CDS             42140..42310
                     /locus_tag="MIV85_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960075.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(42403..42864)
                     /locus_tag="MIV85_000706"
     CDS             complement(42403..42864)
                     /locus_tag="MIV85_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960076.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            43047..43514
                     /locus_tag="MIV85_000707"
     CDS             43047..43514
                     /locus_tag="MIV85_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960077.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            43557..45320
                     /locus_tag="MIV85_000708"
     CDS             43557..45320
                     /locus_tag="MIV85_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBY2960078.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            45328..45936
                     /locus_tag="MIV85_000709"
     CDS             45328..45936
                     /locus_tag="MIV85_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2960079.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            46008..46577
                     /locus_tag="MIV85_000710"
     CDS             46008..46577
                     /locus_tag="MIV85_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBY2960080.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            47095..50634
                     /gene="nifJ"
                     /locus_tag="MIV85_000711"
     CDS             47095..50634
                     /gene="nifJ"
                     /locus_tag="MIV85_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBY2960081.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(51026..51922)
                     /locus_tag="MIV85_000712"
     CDS             complement(51026..51922)
                     /locus_tag="MIV85_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBY2960082.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PGNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPEDNNNSDSTNKPD
                     DNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDNNYF
                     SHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFS
                     KIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(52418..53752)
                     /locus_tag="MIV85_000713"
     CDS             complement(52418..53752)
                     /locus_tag="MIV85_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBY2960083.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            complement(53814..54590)
                     /locus_tag="MIV85_000714"
     CDS             complement(53814..54590)
                     /locus_tag="MIV85_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBY2960084.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            complement(54695..55360)
                     /locus_tag="MIV85_000715"
     CDS             complement(54695..55360)
                     /locus_tag="MIV85_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBY2960085.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            complement(55360..56016)
                     /locus_tag="MIV85_000716"
     CDS             complement(55360..56016)
                     /locus_tag="MIV85_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBY2960086.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIIEGGNL
                     "
     gene            complement(56025..57203)
                     /locus_tag="MIV85_000717"
     CDS             complement(56025..57203)
                     /locus_tag="MIV85_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBY2960087.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTITVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQSKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            57558..58460
                     /locus_tag="MIV85_000718"
     CDS             57558..58460
                     /locus_tag="MIV85_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2960088.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            complement(58676..59488)
                     /locus_tag="MIV85_000719"
     CDS             complement(58676..59488)
                     /locus_tag="MIV85_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960089.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(59491..60450)
                     /locus_tag="MIV85_000720"
     CDS             complement(59491..60450)
                     /locus_tag="MIV85_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960090.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            complement(60556..62115)
                     /locus_tag="MIV85_000721"
     CDS             complement(60556..62115)
                     /locus_tag="MIV85_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2960091.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            62334..63311
                     /locus_tag="MIV85_000722"
     CDS             62334..63311
                     /locus_tag="MIV85_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960092.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            63312..64283
                     /locus_tag="MIV85_000723"
     CDS             63312..64283
                     /locus_tag="MIV85_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBY2960093.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKKIKSVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            64435..66477
                     /locus_tag="MIV85_000724"
     CDS             64435..66477
                     /locus_tag="MIV85_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBY2960094.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNIMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVIKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATILLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            66738..67580
                     /locus_tag="MIV85_000725"
     CDS             66738..67580
                     /locus_tag="MIV85_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2960095.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            67883..69955
                     /locus_tag="MIV85_000726"
     CDS             67883..69955
                     /locus_tag="MIV85_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2960096.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVSTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(70168..71037)
                     /locus_tag="MIV85_000727"
     CDS             complement(70168..71037)
                     /locus_tag="MIV85_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2960097.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNMHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            71201..72655
                     /locus_tag="MIV85_000728"
     CDS             71201..72655
                     /locus_tag="MIV85_000728"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBY2960098.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEAYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            72926..75205
                     /locus_tag="MIV85_000729"
     CDS             72926..75205
                     /locus_tag="MIV85_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2960099.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
BASE COUNT        28663 a         8863 c        12589 g        25322 t
ORIGIN      
        1 taacttttaa aaattagttt tgctaattta caataaaata ggtgtgctgg tgtggctcaa
       61 cggtagagca gctgacttgt aatcagcagg ttgtaggttc gattcctatc accagctcca
      121 gtaaagacta tgtttttagc atagtctttt tttattgttt tttattgttt gatgtatttg
      181 ttattttgta ttaaatactt ttagtggtct aatttacaaa ttataggtat aaaagatgac
      241 acagtttaaa attattgttt taaactgtgt ctgtgagttt taaatcaatc taccatgaat
      301 caccattctg gcatcatcaa attcataggt acatgtagaa agtgtaacta ttttatcatt
      361 gctatttacc ttaataggag atttatacaa tgatttagaa gtaatatcat ttatgtaatt
      421 ttgataatca gattcattgt taaaatttgt ttttagataa tcataatcag attctacaat
      481 ataagcagaa aaaacatcat ataaaaattc ttttccattc aaggttattt ttattttatt
      541 atttttttta aagaagtcag catctttaaa cttatttagg ttgttgaaca tagttttatt
      601 tttcatatta tgtccatata ttatgatatt tttgtcatca atagatttat ttctataatc
      661 cataaacagt gtaccagaaa tagaatcttt tttataaaaa tctttgtcaa gatagtaaga
      721 attatcttta gattgtacaa ctggataatt tatatttgta ttctcaacag aaagccaaaa
      781 tttaaaatca ctgttaatct ttgataaatc ctctttttta tattcttttt tttgaagttc
      841 tgaggatatt ttagtatcat gattgtattt ggtaagtttt gagtatatat taaatccact
      901 gtaaagtatt actaatacta gtataatgtt aattactatt ctatataatt ttttcaatag
      961 atcacctcga gttaaatgta gtttatatat ctatattaca ctatttttga ataaatttaa
     1021 atttttagta taatattact ttgacatgta aaagaatttg tgttaacata actaagtaaa
     1081 ataaatatta agtaagccag ataatcgcat gtaatcttac atgaggaaag tcggagctcc
     1141 atagagcagg gtgctaggta acgcctagtg ggagcgatcc taaggatagt gcaacagaaa
     1201 taaaccgcca ctattgtggt aaggatggaa aggcgaggta agagctcacc agcagctagg
     1261 cgactagttg gctatgtaaa ccccacctgg agcaagacca agataggaat aaagagtgct
     1321 gctcgtactc tccggtaggt aggtcgcttg agcctattgg tgacaatagg cctagaaaga
     1381 tgattatcta atacagaact ccgcttatag acttgcttaa ttatttcgat agtcaaaaac
     1441 atcagtttaa actgatgttt ttttatttgt aaatttgtct aatctacttt taaaattttg
     1501 aggaatattg taatataagt tagtacagat attaaaaatg gtataatata agatagatat
     1561 aaaaagaaaa agtaaaatga tgtaaataat atgatatgat ataagatgta gcaaatttag
     1621 taaataatta tttagatatc ataatcaaat tagcaacttt gcacaatgta aatattacaa
     1681 taaaataatt gatttaagga gtgaaggttt tgagtgaaaa taatataata agaaacactg
     1741 ttttaaatgt cacagcaagt tttttaaaac aagagtctaa aataaatgaa aagctagatg
     1801 gtgttttgga aaagaaattt gaaaaagtag aatttaatga agcaaaatat gcagagcttt
     1861 taaaatttaa tatattgttt tataagacat tagcaagaaa tacagaacca cttattggca
     1921 aatggatagt agataagtac atacctgaaa tagatgaatt agaaaaagat ttagagttaa
     1981 ctacagcaaa atgtagaaag tatgtaaata aggctatgaa agagggatta gactctctaa
     2041 aagccaatga tttaaatagt tttttagctt atgataaaat ggaactatca gagagaagaa
     2101 gacgtttaga aaaggattat aaggttttaa acctatataa agaccttctt aatatatctc
     2161 ttagaaaaat aagtttagaa aagaaagaat gtggagattt atttcttaaa aatcaagcag
     2221 atgcgaaaag agaattaaaa agagaaatta tattctgtgt aaacaaaata ttagctagta
     2281 ataaagatgt ggtacctaat aatgtggaag agaataacga acaaaacaaa gtagaaataa
     2341 aagcaactga aattgaggat ttgcaattag gtaaagataa ttcagaaaat gacatgctac
     2401 taaatgaaat taaaaattca aaagtaaaac atgaatcaaa atcaaatgat atagaatcga
     2461 agtttataga taagttaaat agcttaaata atgaaagtat atctcaaaca atacacaatg
     2521 aatataagaa gttatgtgga ttagaagaac ttcattctgt tgaagcatat ggttttggca
     2581 aagaaattat taaagatttt gcttgtgcaa cagttgtatt agaattttta aagagaagaa
     2641 atagagacct tatagaaggt gcaatgagac tgactataat tggagaattt ggtcctgaaa
     2701 attttaagga atttgtggac tatgtaatta aaaataaaac agaaattagt gaagatacat
     2761 ggaataaagc acagaatcta ataaaagata actatagtga attagaaaat catgaaattg
     2821 catcaaaaag aactagaaga aataaagata tcgatattga agaatacatt tacatgataa
     2881 aaaatgcaga taaagatatt tgctttagaa gtagtatttc aatagaagat gatgctgaag
     2941 aagggactaa agaagaagta gatagtaata atcaagatat aggtgacgtt gtagaagata
     3001 aagatactac agataaagag tacgacagca ataaagaaga tataattgaa ccagaaaata
     3061 aaaagagtaa aaagaaggct aaattatttg gatttattaa aaaagacaat gaagaagctg
     3121 aacaagaaga agagaattta aatgatattt ctccagatat aattttagat aaaccagttg
     3181 aaaatcatca agtgaaatca gaagaaatag agcaaaatga attgaaagaa ataaaacaag
     3241 aagaaccaag tcaacatata gaagaagaac gtagtgtaaa aatagaaaaa ccaataaata
     3301 ataacttaga tgaaaaagta tcttcaaata atgaatcgaa gcttgaaaaa gaaagtaaaa
     3361 acttagaaga taaaaaagca aaagaaataa aagaagaaaa attagaaaat gaaaaatcag
     3421 tagtaatacc tattaaaaag aaagaaaata gtaataaaaa atctaaaaat tcttctaagg
     3481 acaaatatag agaaaacaag aaagaaatga aaaattatgt atcagataaa gaagattctt
     3541 tagatgatga agaggttgtt tctaagaaga gtagattaaa agaaactatt atagcagtag
     3601 ttatagtggt tattgttggt gtaggatatt ttataacagt aggcaacaat aagaaaaatg
     3661 ataaagagaa tattccaaag tcatcaactc aacaacaagc taacaataaa ttaactgaag
     3721 aagagaaaaa agcacaagct gaaaaagaga aaaaagaagc agaagaaaag gcaaaagctg
     3781 aaaaagaggc tcaagaaaaa gcacaagctg aaaagaaagc aaaagaaatg gaagcatata
     3841 aagatggtaa aggtgtatat tacactgttt atgcaggttc acttaaagtt gaaaaaacag
     3901 caaaagaaac agcaaaagaa tatgaagcta aaggtatttc ttcaacaata attcaagaaa
     3961 atggatacta taaaataaaa ataggtgatt attctcaata tggagaagca caagaaaaat
     4021 gtaatgaact agctaagaag tctattgata catatatagc tatgtatgat aagtactatg
     4081 attataagtt agaagaatta aaagaatcag ctccttcttt gagtgctgaa gaacttaaac
     4141 aaaaatatga agatttaaga agtgagttaa agaacaaatc tggatatcgt gaatatgtta
     4201 aacatttaga taaactttat gaagaaatag ttgaaggtgc ttagagcatt ataaaaaagg
     4261 agaaactatg tctcagaata aaaagtatta aaaaaaatat tatttgtttt gagacatttt
     4321 attcaccttt ataaaatact tataattctg tttaggtggt gaaggtatgt tgaaattagg
     4381 agaaaaaatc atatatgagc tttcagatgg gtttgagctt agtggcataa gtagatactc
     4441 aaaagaatat aaaaagcttc atataacaaa tctagggaat ataataatca gcaaatcaga
     4501 tgaagttaat gaggatacag gtgtaaaata tatatatagt ttttcagaca ataaagaaaa
     4561 attagaggca gttttagaag attctcaaat aattgtctat ggaaataact tgccttttta
     4621 cataaaaagt gaaaattcaa gtaaaaatgt tacagcaaat ttgactatga aaataacttt
     4681 ggatgaatat gatttaatct gcaaaagtca aagagaattt atattctatc taaaggataa
     4741 tatgactata ttaagtttag atgacaataa gttttatatg ggtggaatta ataaagataa
     4801 tgagaagttt atatttatca gtgggaaaaa tagatttgaa ataaattttg atgatataga
     4861 aagatacatt ttagaagata aaagagtgtc attgaaggga tactttcata tggaaagaga
     4921 ggggattata gtaaggtctg tatctatatt taataacaat atagatagtg tagtcccatc
     4981 tgatttaaat gagagagtta aagataacca aaaaatagga aatcttccta aagattgtga
     5041 aatagtattc tgcaagatat caggaaatat agatggattt gattataaaa acacaaacat
     5101 gcttttagta aaatatcaag accaattaat ttttataaat aagaaatcta agaagactat
     5161 tgtaaagtca gcgaaagata attgttctaa gttaaattta ggagaagata taatattata
     5221 tgataataaa aatgtattta acctacatat aaatgataaa aatagagaaa ttatgcaaat
     5281 agatgaccta aaagatatag aaaatgaaat agtgggatat acattaaaac atgctccatt
     5341 ttttattcaa gaagatttcg atagcttgac tattctaaag tcttttcaaa aagaaatcat
     5401 atctataaaa aatagtgata taaaagacat tgtaattaat aaagaacttg aaaacgaaaa
     5461 ttctaatttt gtagaaacgg aaataaaatt taataatcaa aaagtacttt taaacttaag
     5521 taaaagtatg gttcaaaaac ttatgcaaga tgtatttata tatgcaaagc aacctctact
     5581 taaagaaaat tctattgaag tgatatataa gaattggtct aaagctatga atgatatgat
     5641 aatatttaat ttctttggaa atatttacta tatgaaatct gaatttgata agattttaga
     5701 aaaagagtta aatgatgaaa taagaataga agttataaat tcactttata agcaaataca
     5761 agaacaaaga aacaatttag atttattgtc agcatatatg ccaagaatat tagaaaatca
     5821 agaaatagat ttgtttgaaa agtataatac taaacttgat gtacaagtgt ttaagcagat
     5881 taaaaatcta ttgtctgatt tatcatataa tataagcagt tatttaaatg aagttgaaaa
     5941 aagtttagac aatatcatct ttgtaatttc aggagaagat aagaagaaat acaattatag
     6001 aatgttaaaa gaaagtgaaa gtgcaagtct tgatgtattt ttaaaacaag ccatatcaag
     6061 attaaaccat ttagtagaaa atatgtatcc ttattatgta gatgaaacta gtagggaaat
     6121 gtttaagtta tttgagttat tgtggaaaaa ctatagaaat attgatgatg atagtataaa
     6181 agaaatatta ttcgagagaa taacaaatac atatgtattt aaacaattga cattaaataa
     6241 tagtacaaaa gaaagaagaa aagacataat tgaaaaaata tataactctg ttgattatgg
     6301 aaccaataaa ctagatgaaa atatgttttt cacaggagga ataaagtatg tcaagtaaat
     6361 acaatgtttg gacttttaac tatgagttct taggattgga ctcaggggat gaaaaaaata
     6421 atgaagttta ttacgagatt gatttagatg aaattttaaa tgaaaactat atagatgaag
     6481 atatagatag tggtttagat tctgatggaa atagtatttt aggagaatta atatcagaaa
     6541 tggatataga tgaggatgtc agtgttgata tgacatatca agaactagaa gttgacttag
     6601 aagatttaga ttcttatcta gatgaagata tagatagtga tataaaaggc atcttagatg
     6661 aaatttagta cctgtataag ttttggataa aatataaaca atacaatatt aacttataaa
     6721 actaaaggta gatgaaattt catctacctt atattatctt atagcattaa atattgggat
     6781 aatatagagt ttgaagaaaa agtataaata tggtatatta atttggtaca atagaaaatt
     6841 tacgaagaag ggtgaaaaaa tgcagatgac agttaaaaaa gcaataatac cagcagcagg
     6901 gctaggaact agatttttac cagcaacaaa atcacagccc aaagaaatgc ttcctatagt
     6961 agataaacca actttacagt atataataga agaagctata gaatcgggaa ttgaagaaat
     7021 tcttataata acaggtagaa ataaaaaatc tatagaagat cattttgata aatcagttga
     7081 attagagtta gaactagagc aaaaaggtaa gacagagatg ttagaaatgg taagagacat
     7141 atcaaatatg gtaaatattc attatataag acaaaaagag ccaaaaggtc ttggacatgc
     7201 aatttactgt gcaaaaagtt ttataggtga tgaacctttt gccgtattat taggtgatga
     7261 tatagtagat tcagatgttc cgtgcttaaa acaattaata gatacttata atgagtataa
     7321 aacaactgta ttaggtgttc aaaagatagc taaagaagat actaataaat atggtatatt
     7381 ggatgtaaaa catatcgaag atagagtata taaagttaaa gatatggttg aaaaacctgc
     7441 aattgaagaa gctccatctg atatagctat acttggaaga tatataataa ctcctgcaat
     7501 atttagcata ttagagaaac agacacctgg taaaggtgga gagatacaac tgacagatgc
     7561 acttcaaact cttggaaaac aagaggctat ttatgcttat aactttgaag gtagaagata
     7621 tgatgtggga gataaaattg gttttttaga ggcaacaata gactttgctc taaagagaga
     7681 aaatttaaaa gatgatttaa tggactatat gagaaaaaaa gtaagtgaaa aataaatatt
     7741 agaaaagagg taattacaat ggcagtttta gtagctggag gagcaggata tataggaagc
     7801 catacagcaa tagaactttt agaatcaggt tatgaagttg ttatagttga taacttaagt
     7861 aatagcaact caatagtggt tgatagaatc aaggaattat ctaaaaaacc agtaaaattt
     7921 tataatattg atatcagaaa taaagatgaa atgcatgttg tatttaaaga aaataatatt
     7981 gaatcaatta tacactttgc agctttaaaa gcagttggtg aatcagtaga aaaaccaatt
     8041 gaatattaca gcaataatct aataagtacc ttaaatttat ttgaattaat gagagaatat
     8101 ggtgttaaaa agtttgtatt tagttcttca gctactgtat atggagaccc acatacttgt
     8161 cctatattag aggattttcc actttctgta accaatccat atggaagaac taaacttatg
     8221 atagagcaga tgttagtaga tatatcaaaa gcagataagt cattggatat agctctttta
     8281 agatacttta atccagtcgg tgctcataaa agtggtagaa taggtgaaga accaaatgga
     8341 gttccgagca atctaatgcc ttatataaca aaaatagcag taggtaaatt gaaggaattg
     8401 agtgtttatg gtaatgacta tccaacacat gatggaactg gagttagaga ctatatacat
     8461 gtattagatt tagctgctgg tcatgtaaaa gcattacaaa aattagaaga aaatccagga
     8521 cttgttgttt ataatttagg aactggaaag gggtatagtg ttcttgattt agtaaaagca
     8581 ttttctaaag caagtggaaa agaaatacca tataagattg taggaagaag ggctggagat
     8641 gtagccatgt gttatgcaga ttcttcaaag gcagaaaaag agcttggatg gaaagctaag
     8701 tatgaacttg aagagatgtg tgaagattca tggagatggc aaagtatgaa tcctaatggg
     8761 tatgaagagt agaatacata cttatatgta taaatgtaac aaatttgtaa atataaggta
     8821 ttggtaattt tatgttataa ttagacacat gtagtaatgt ttctaaaaga gggggaagtt
     8881 atagtgaaaa aaagtctaaa aaagtattta gtactagcac tgactttagt tttagtattt
     8941 gcatgtggcg taccagaatc aagcgcagcc agtaaacatg tgattatagt aaattcaaga
     9001 aaaaatactc taggatattt tgtaaataat aaacttgtaa aagaatttag agttgcaaca
     9061 ggtaaaaagg ggtcagaaac accaacaggg aaaacaaaag tagttaacaa gataaaaaat
     9121 agaccatatt ataaaggtaa tatacctgga ggaagtccaa gaaatccatt aggagataga
     9181 tggatgggat tagcattaaa aggaacttat ggagatacat atggaataca tggaaataat
     9241 aatgagagtt ctataggaaa gcatatttct ggtggatgta taagaatgca caataaagat
     9301 gttagatggt tatttgacca agttcctgta ggttcagatg taattataga ttatagtaac
     9361 gacagctatg taaagatagc ggcaaaatat aagataaatc taaatcaaac aggatggaaa
     9421 acagaaaatg gtaagaagta ttatgtaaaa tctgatggaa cataccaaaa gaatagttgg
     9481 ctaaaagtaa atggaaaaat gtattacttt gatgcttcag gagtaatgca aacaggatgg
     9541 aaaacaatta ataacaaaaa atattattta ggaactgatg gagcaagagt atctggatgg
     9601 aaagtaatag acggaaaaac ttattacttt aactcagatg gagtaatgca aacaggatgg
     9661 caagaaaaga atggaaagaa atactatcta ggatctgatg gtttagcagt aacaggatgg
     9721 caagaaatag atggtaataa gtattacttt gacaaaacag gaataatgca gacaggatgg
     9781 caacaaatag atggtaagtc ttactattta gacaaagatg gaaagatgct aactggttct
     9841 caaaaaatag atgggaaaga ttatactttt aatgaagatg gaactataaa tcctacatgg
     9901 gatacaatta taggtgcaaa tagatttgat acagctaaaa agataagttc agttggaaac
     9961 tggaatgctg atagttcaga tactgtaata ttagtaaatg gtaatgcaat agctgatggt
    10021 ataacagcaa ctcctttagc aagtagctat gactcaacaa tactacttac taatacagct
    10081 aatttaccaa ctgaaactgt tgaagaaatg aagttattag cacctaaaac agtaatcttg
    10141 ataggtggag aaaatgcaat aagttctaaa ttagagcaag aaataaaaac tactttcaac
    10201 acagaaacaa agagaatagc aggtcaagat agatatcaaa ctgctacaag aatagctgaa
    10261 gaacttggaa atcgagaaga aataaaaact gcatatatgg tttctggaaa tggggaggca
    10321 gatgctttat ctgtagcttc taaagctggg gaagaaaaac aacctataat attagtcaat
    10381 aaagatggaa ttacagaaga atcttataaa tggctaacag aaagaaaatt agaaaatgca
    10441 tactttatag gtggaccaag tgcaattaac gattcagtaa tagcaaaaat gaatgatata
    10501 actactgaag atatttcagg aaatagaata tatggagata gtagagtaga tactaatgcc
    10561 aaagtgatag aaaaattcta tggagatact gatttacagg ctgtattagt tagtaaatca
    10621 gatgctttag tagatgcttt atcagctgga ccattagctg taaaattaca ttcaccaata
    10681 gttttaatgg ataattcagg attatcatca gagcaacaaa gagtatttgc aaataaaaaa
    10741 gttgaaactc cttatcaaat aggaggcgga gtatcttata tagtaatgga taaattaatg
    10801 gatattcttg caaaatagta aaaatatata ttgaaaaata attataattg agatgtgaaa
    10861 ttcaatcaat aaaagcttga ttgttttaca tctcaatttt ttagtataaa attaagttta
    10921 agttatataa aaatcttgga atatttttaa aactcatata aaatgaatat agatgctatc
    10981 atcatatgtt aagagggtga gtaagattat aaagaaaaaa tatataatgt ttattgatga
    11041 aagtggaaga gctgatataa atcatgaaga cccatttaca ttgacaggag taatttttga
    11101 atataaatat gcagtaagtc aaggcgatta tgtatgttct ttgaggaaag aaatggatgc
    11161 atttaaagag tattgttttg gaaccagtaa cataggaata catttgacag atatatcaag
    11221 aaaatcaaga gcatttgaga agtttgatga ttcacagatt aagttattct atgatgagtt
    11281 gcctttattt ctatctagat tagagtgtac tataatatca gtaacagtag ataaagctag
    11341 attaaagaaa tattatgcac cttcaaagga accgtatgtt gtggctttta tacatgttct
    11401 tcagaatttt tattcatttg taaataatga aactgtagaa tctgcacgaa tagttataga
    11461 gtcaagggat gatgtctcaa acttaaaagt acaaaaggcg ttttttgatg tatttaataa
    11521 tggaacaata tacttagata tagatgaaga attaagagat aaggttaagg gttttataat
    11581 tgccaaaaaa gaagatgctg actatagaga aggtttagaa atagcagata ttttatgtaa
    11641 tcctcttagc agagcaagaa gagggttaat agaagctaat ccaaagtgta tgcaatatgg
    11701 agaaaaaaac aaaatattca aatctgtcag aaacaaaata tatactccaa cgagtgtgaa
    11761 tgatataaga aattggggat ttaaagaagt tcctattgta gagcctgttg gaccatggct
    11821 tgaaaaaatg cgttagatac aattgacaaa ttttaaaaaa tctgatataa tgtaagtaac
    11881 ctagttattc aggaactgaa tccagttgct gttgtataac gataattact gagactcgga
    11941 tgccgactgt cagttaggaa tctatacttt taaaagtata gattttttta ttttataaaa
    12001 agaataaaag aggatattta aaaataaccc ctttattaat aaattataat tgagcgtttt
    12061 taatgacaaa gtttttaaag tttttaattg caggaggcaa atatctatct tttataaatg
    12121 ctaagtaaaa gtttctttcc caacttgggt gaataatctg aattactttt acttttgtaa
    12181 agctaagcat attcatattt gggactacag caattccgaa attttttgca actaatccag
    12241 caattacttg gtcttcctct acttcataga ctatattagg ctgttgattt atttttttaa
    12301 acatatcatc aattatatat ctaagaccac ttctctgatt aaatactatt tgaggataag
    12361 gtatggtttc ttttaaatct atagtatcct ttgcagctag tggatgacta tatggtacaa
    12421 ttagtactaa atcttgtttg gcaacaggta taaattcaat tcccttttct ttttcaagtt
    12481 tcgaacaaaa tgcaatatca tattttcttt ctttaagacc ttgaataatg tcagtagtta
    12541 caccagtatg aaatttaaaa tctattgatt tagcaggatt agattttaaa aatttgtgca
    12601 ctatgtctgg gataaaatca gtaccaagtg ttctaagaaa agctaagtct atttgtcctt
    12661 caccagtacc agttattttt aatgatttta cacttgaatc taaaatttct aatgattttt
    12721 ccacatcttt taaaaatatt tttccatact tagtaaggac tatatttcta ccttcttttt
    12781 caaatagagc caccccaagt tcattttcta gtaaagaaat agcatgactt aagcttggtt
    12841 gtgttataga taaattttct gccgcttttg tatagtgttc taaatgtgcc aatgtaacaa
    12901 aatagcgtaa gtgatataaa ttcaattttt gttcatcctt tcataggtat ttttatttat
    12961 atatttgtag aagttaacct ttaagatatt tttacatttt tattatatat gattatagag
    13021 taagaataaa agcttttaaa aaaatttatc gttttttgtc tgaattataa gataaatata
    13081 tttatacgac ctaatagaaa aatacaagaa ttatcttata aataaaatct ataaacaaaa
    13141 tctatgaatt aataggaaat tatcaatttg ttattagtaa agtctcgtga tacaataaat
    13201 ttataaaatc tagataaata gaaatcaaaa aatactttta tttttaaggt aaaataatac
    13261 tactagtagg ataaataaaa atataaaatc aaaaatacta ttaattataa agaaaataaa
    13321 gggggcaaat ttaagctatg aataatcaaa aaaatcttaa tattccaatt acaattagtt
    13381 cttatacatt gggaacagaa gtttcattcc gtgatagagt tcgtattgca aaagaagctg
    13441 ggtttgatgg tattggattg cgtgctgaaa attatattga tgcaaaaaat gcaggtgtta
    13501 cagatgaaga aatgattgca attcttaatg aatatgatat gaaagttaca gaagtagaat
    13561 atataactca atggggaaga gaagaagata gaacggaagc tcaaagagaa aaagagcaaa
    13621 atgtttatca tatggctcac ttatttaatg ttaaacatat aaattgtgga ttattagaga
    13681 tgataccaga agaacaaatt ataactgcat tgggagaatt atgtgacaga gcaggtgaac
    13741 ttattatagg tcttgagttt atgccatata gtggtgtacc agatttggct actgcatggc
    13801 gtgttgtgaa aggatgtaat cgtgaaaatg caatgcttat attagatact tggcactggg
    13861 ctagagcaaa gcagacagca gaggaccttg cacctgttcc agcagataag atagtatcaa
    13921 ttcaagtgtg tgatgtttta gaaactcctt atgaaaaact tagggatgaa tcactacatg
    13981 accgtttggc tccaggtgaa ggatatggaa acacagagga atttgtgaaa ataataaaag
    14041 aacacaatat atcaccaaga gtcatagggg cagaagtaat atctgattct ctaatatcta
    14101 aagggttatc cactgctgct gaaactgtat ttaatgcaac taaaaaagtt ttggataaag
    14161 catggtctga agtatctcca aaataaactt atataatata aaaatataca gagtattata
    14221 atataaaact tgaaaggaag gaaaacctta tgaagattag ttctatgttt acacctataa
    14281 gaattggttc aatgacagtt ccaaatcgtt ttgtagttcc ccctatggga aacaattttg
    14341 caaacacaga tggtacttta agtgaaactt ctaaggctta ttatcttgag cgtgctttag
    14401 gtggttttgg attaataact atagaatcta gtgttgtaga caaaaaagca aaaggaggtc
    14461 ctcgtaagcc ttgtttatat gatgatagca caatagatag ttttaaaaat gtaatagatg
    14521 cttgtcatga tgcaggttcg aaggtatcta tacaattaca acatgctggt tctgaaggaa
    14581 atgaaaaagt agcaggacat ccattaaaag ctgcttctgc aatacctgca tcaaatggtc
    14641 gtaatacacc actagcaata acaacagaag aaatatatga acttatagaa tcttatggag
    14701 atgctgcatt acgtgcacaa aaagctggtg cagatgctgt tgaagttcac tgcgctcatg
    14761 gatatctggt tagtagtttt atatcacaaa gaacaaataa gcgtgtagat gagtttggtg
    14821 gatgttttga aaatagaatg agattacctc gtcttatcat tgaaaatata cgtaaaaaag
    14881 taggaaattc tctagcaata ttatgtcgta taaacagcac tgatgatgtt ccaggaggaa
    14941 ttgatgtaca cgatagttca gtaatagcag catatctaga agattgtgga atagatggac
    15001 ttcatgtttc acgtagtata catatacatg atgaatatat gtgggctcct acgactttac
    15061 atgctggatt cagtgcagaa ttagttactg aaataaaaaa agctgttagt ataccagtaa
    15121 taacagttgg acgttataca gagccacagt ttgctgagtt aatggtcaga caaggaagat
    15181 gtgatttagt agcattcggt agacaaagct tggctgaccc agaaatgcct aataaagcta
    15241 aaaatggaaa actagacgaa atgataccat gtattgcatg cttacaagga tgtgtaccaa
    15301 atatgttcca aggcaaacct atagcctgtc ttgcaaatcc tatattagga catgaagcag
    15361 agcttaagcc agctgaaatt agcaaagaag ttcttgttgt tggtggaggt gttggaggta
    15421 tgcttgcagc atgggtatgt gctaaaagag gacataatgt aactttagtt gaaaaatctg
    15481 aagttcttgg tgggcaaatg cgtttagctg catatcctcc agggaaagga gatattacta
    15541 acttagttag aagttatatt tcaaaatgta atcaatatgg tgtaaaaata tgtactaata
    15601 cagaagctac agtagaactt ataaaggaga aatcacctga tgtagttatt atagctactg
    15661 gagcaactcc acttgtactt cctataccag gaatcaatga ttcaggatta attcatgctg
    15721 tagaccttct tgatggtaaa aaatcttgtg ggaaaaaagt acttgttgtt ggaggtggaa
    15781 tggttggatg tgaagtggca gccttccttg gagaacaaga acatgaggtt actgttattg
    15841 agcttagaga agaagttggt gcagatgtaa tttcagaaca ccgtaaattc cttatgaatg
    15901 attttgaaaa ttataatata cataccatta ctggtgcaaa agtttctaaa ttttatgatg
    15961 atggtgtcga ctatttactt acagatggca cagagcatga tttaaaaggt tttgattcag
    16021 tagtacttgc tatgggttct cgtaattacg acccattaag tgaagttata aaagaagttg
    16081 taaaagaaac ttatattgtt ggtgatgcag taaaagctcg tagggcatta gatgcaacaa
    16141 aagaagcttt tgaagtagca ttaaatatat aaataataaa taaatttttc tttgtaaata
    16201 actgaatagg ttatttgcaa agaaaatgat aatattgaga ggagattata gttatggaaa
    16261 tttcaggtag aacaggatta tttgcattaa taggtacacc ggttggtcac tctaaatcac
    16321 cagtgatgta taattatagt tttaagaaat tagatttaga ttatagatat ttagcctttg
    16381 atatcacagt agataaggta aaagaggcac ttttagcaat aaaaactttt aatataaaag
    16441 gagccaatgt tactatgcca tgtaaatctg ctgttacaga atatatggat gaactttctc
    16501 cagcagctcg tataattgga gcatgtaata caattgtaaa tgacaatgga aagttagttg
    16561 gtcatataac agatggagta ggctatgttc gtaatttaaa agaaaatggg gtagaagtta
    16621 aaggtaaaaa gattacaatt atgggtgctg gtggtgcagc aactgctata caagtacaat
    16681 gtgctttaga tggagcaaga gaaatatcta tctttaatcc taaggatgat ttttataaaa
    16741 gagcagagca aacagttgag aatataaaaa aagatgtacc agaatgtgtt gttaatctat
    16801 atgatttaga agatacaaac aaactttatg aggagataca atcaagtgat atattgacaa
    16861 atgcaactct tattggtatg aagccttatg acaatgaaac aaatataaaa gatactagtg
    16921 ttttaagaaa agatttagta gtaacagatg tcgtttataa tcctaagaaa acaaaaatga
    16981 ttgaagatgc tgaagctaat ggatgtaagg ctattggtgg attaggaatg ttattatacc
    17041 aaggagcaga agcttttaat ctatatactg gattagaaat gcctgtagaa gaagttaatg
    17101 aattatgctt taaatagata agagtaatat cttaaacaat gaaaaaacat acgtatttca
    17161 atatttttaa taataaatta caaattgtca tagtgggttt tgcctcatag tccagttaaa
    17221 tttgaagttt taactgacta tactttaaat ccattatggg gatgagttta ttgtacacaa
    17281 aaatgttaat aaattaacaa gaatgggaga aaaattatga acaataaaaa atattatcct
    17341 actgccatag cgttgtattt ttcatatttt ttacttggta ttggaatttc aattttagga
    17401 caatacaaac cagaattttc atcaatgtgg ggggctaaaa cattatcaga tggaacattg
    17461 gatgtaagta ttgttttagc tgttattgct gcactaggat tagggagact tatatcttat
    17521 ccatttgcag gacctatttc agataagtat ggaagaaaag taagtggtct tataggaaac
    17581 tttctacatg caattttctt tgttggaatt gtattttcac caaattttta tatagcatat
    17641 gtatttgcaa taattggagg ggcagcaaat tcattcttag atacctgtgt aactccttct
    17701 tgtatggaga tatttgctag tttaggaaca atagcaaata tgtttactaa atttacaata
    17761 gctttagcac aatttttgct tccttttata attggatttg ttgcagcaaa ttcaatatca
    17821 tttaaagtta tttttatagt aacagcgatt cttattgtag tagatgcctt tttgatagct
    17881 gtgttaccat ttccaccagc taataatgtt attgataaca aaggcaaaac agttaaatca
    17941 gagaagatga aatttacacc aacaagtata gctcttgttt gtattggatt tacatgtaca
    18001 tctacatttg tattatggtt aaattgtaat caggaattgg gtaaattgta tgggatggct
    18061 gaccctacaa aaattcaatc cttttactca atgggagtaa tatgtgcagt attaataact
    18121 tctttactta ttaaaaaata tattaaacca ataagaatat tagttatata tcctataata
    18181 gctttactta tgctattagt tgtatatttt gttcaaactc caactatttg tatgttaggg
    18241 ggatttgtaa taggttattc agcagcagga ggtgttcttc agttaacaac gtcaactgca
    18301 aatgaaatgt ttccaactaa taaaggaaaa ataacatcta tagttatgat tgcatctagt
    18361 atagcaaact atgttatttt aaatatagca ggtattatta caaaatcagg gggagttaat
    18421 ggaccaaaat atgttgtatt gtttaatgtg gcaataacat ttgttggaat tttacttgca
    18481 ttgtttgtaa acatgagata tgaaaaagaa aaagtgtatg attatgatgt ctaatattag
    18541 tataatatat gcatagagaa gtctaaatct aggatagatt tttattaaaa gtaattaaaa
    18601 ttaataagga tattatttac agttataaga tagggtattt acataattaa taataaggat
    18661 attactagaa tttcaatttc tagtaatatt tttttgcgta taaatgtaaa cttgatgaaa
    18721 taagtagtat aatcaatata aattacatca tgtaaaggag gataatttgg tggagaatgt
    18781 ttttaagcga ttgcaggaat ttaatggtta tgatggatac aaagaatcat ttgaaatgaa
    18841 ttacctatgt atatatgaaa gtataccgtt aagagaacaa gtagagcttg caaataatct
    18901 agtagatgaa attttaaata tgtataaaag tgaatctaat gaaatttatt tattggaggg
    18961 tagtaattct aagtctttaa tttgttattt cgaaattttt atgaaaaaga taaatacttt
    19021 ggtaaaagaa atgattattg atgagaaatg gttatataaa ttaactaaag aattaatata
    19081 taagagtaaa aaagttgagt atgtaaaact agggttagtt ttaagtgaga aatatctaaa
    19141 tgtagaaaac ttaagagaag ttgtagatac attttctaaa tctggagaat acgtatttta
    19201 tctgagtaat actattaaaa aacttgaatt ttacaataca tatttattta atttatctaa
    19261 aaaggctaca ggttcaataa aagtatttgc tattgttaat atggaaaatt tagattctaa
    19321 aataaattcc tatctaattg aagatggtta taaggataca aagtacgaac gattattgat
    19381 gaactatatt atttcaattg tagatttgaa tgaatatctt gaaaaacgag atttagataa
    19441 agaaaagata aataatttag cacgtcttat atgcaattac ttgctaagtg tagaatttaa
    19501 atatataggt aataaattag aattagtgaa tcgattttta cctactgtag taaattatgg
    19561 gactaacttt gaaagtttat attcaatttt cctaatagct ataaacgtct taaaagatga
    19621 aaatatagag tgcaataaga ttgaatttga aaaagaaata aatggtatct tgctcagtga
    19681 aaaatggaaa aatatatatt ttgaagcatt aagagatgct agtggaaaaa cagaagatat
    19741 tataaaaatg tcagaaattt atgatgtaaa cttatctttt gatgacttgt tgccatatct
    19801 aaatagagat attagagatt ttgaggtata ttggcatata tctaaaaagg gaacgacaag
    19861 ttctagatta aaattattaa atttttttga agagacgttt aaaatagatg atttaattgg
    19921 aaaaatgaaa gatatagaaa aagataaatt gactcaagaa tattatgatg atatgttatt
    19981 ttttattgtg cttaaaggaa gtaaatcact atatcctgaa ggaaagaata tatctttaaa
    20041 aggaatattt ggaaatataa atgaagtaag aaaagaatcc ataaatatct taaaaagata
    20101 cagagagaaa ctatctcttg aagaattaaa aattgttaaa gaagcgtatg aaaaagaaaa
    20161 aaatgttata ttgaaggatg aattaagaag agtattatat gaaagtaata atttaaaaaa
    20221 agaatttgta aatattgaaa aaataaaagt agatgaacat ggtaaggata tctatttgac
    20281 ttcaatagct gttgctggtt caaggtttag aaatagagaa tatcttgaaa aagaattgga
    20341 gaaaagtaag atatactatt taactagaga gaaagataat ctatatgatg aaaaagctat
    20401 taaaatagtt ggtgaaactg gatatgtgat aggctatgtc ccaagaaaag aaaactatat
    20461 tttgagcaat ttattagatg gaggaaaact gctgtattgt agagtaactg aatataattt
    20521 atatgaagat tgtatctacg caaatgtgta cttgagttat aaagatgtaa ttgaaacagt
    20581 tgaaaactct ttaaagatgg ttttagataa gagtagaata aaacttataa actaagacgt
    20641 ttatatattg cttagatgat gtaatcctaa ctgattggtt attttttctg gaattatggt
    20701 gtattttatg agcaatgcta atgaatataa aataaaaaaa caattgtttt gtatatatga
    20761 tgtatataaa tatatttata tattcatatt tacaaaacaa ttgaaattta tgttatttta
    20821 taattttaaa tttagatgga attttaactt ctgctttatc ttttatttta gaagcttgtt
    20881 ttttaacttt atttaataat tcagattcat ctacaactaa tacttttctt tccttcatca
    20941 accatttacc atcacaaata gtagagtcta cattttcact agtcatagaa taaactatat
    21001 ttccaattgg attatgcatt ggtaaacaat gaattgtatc tggatttaga ataatcatat
    21061 cagctttttt tcctacttca agactaccaa tttctttttc tagtaaagca cattttgctc
    21121 catttatagt agccatttct aagacttctt cagctggtac gacagttggg tttaaagttc
    21181 ttcctttatg tattagtgat gtaagataca tgtccctcat aaggtccatt ctattatttg
    21241 aaggagctcc atcagtacca attgaaacag gtattccttt ttctaacatt tcaggaattg
    21301 atgcaaaccc tagaaccact ttcatagctg aacctgggtc atgagaaact tttacatcat
    21361 gtaatctaaa taaatcaatt tccttatgag taagccaaac tgtatgagca gctaaaagat
    21421 ttggtcctaa tacacctagt ttatcaaggt attcaactgt tccaactcca ttgttttgct
    21481 ttacaaatga aatttcatca gctatttcag caatatgcat atgtatacct gtattgtatt
    21541 tatcagctag ttctttagtt ctaacaagta attcttcagt tgtattaaaa atagttctta
    21601 atgcaaacca tattttaatt ctctcattag atgtattatt aaacttatgg aataagtcta
    21661 attgagtgtt gatttcctca tcagtagttt tttgccatgc ctcaggaaga ccatctcctg
    21721 tatccataac tgatttagct aaacaggctc taagtccagt tttatcaaca gcttcaacca
    21781 tagcatctac atattgacca ccagattcta aaaatgtagt gacaccagat tttatcaatt
    21841 caacacaaca tgcagtagat gaaatcaagg aatcttcata attgaagcta ctttcgtatg
    21901 gccaaattct ttctctaagc caagttaaaa gtacaacatc atctgcaaga ccacgtccta
    21961 attgttgaga taagtgaaca tgagtattga ctagccctgg cattagtatt tttcctttag
    22021 catcatatat ctctgcatct ttatctacaa tattaatatc aaacttacca acctctttta
    22081 taatattatt ttcaataagt atgcttccat tttcatatac ctctctatct gcattcatag
    22141 taattagata tgcatttttt ataagtaatt gtgacataaa caccactcct tttctatata
    22201 tttttatatc tatatattat gataataaat tttctataca aagttaatag caaaatcaat
    22261 ttacatataa agtgattttg ctatttataa atttaaaata aataagattt tattctatat
    22321 aatttaaaat attgacctag aactatttaa aaatattaac ttagaactaa gtttacaact
    22381 gcaagtaaac ctataatcca aagtgtaata ctgattttat cagtttcttt agctactaca
    22441 tgcattatta tatatgaaat aaatccaaag cataaaccaa tacttatact ataagttaaa
    22501 ggcatcaata aaactgtaac aaaagcaggt acagctattt tgctatcagc aaaatcaatc
    22561 tgttttatgc tttcaaacat gaatacacca accattacaa gtgcaggagc tgcagcgtaa
    22621 gtaggaacta taccaagtaa tggtgtaaat ataagtgtag ctaagaataa tgctgctgtt
    22681 actattgaag caagtcctgt tcttgcacct gctgcaatac cagaagcaga ttctccaaat
    22741 gttgtaacag tactagttcc taagaatgag cctattaaag tagaagaaac atctgcatat
    22801 aacattcttc ctaaatcttt tatttcacca ttctcatctt caagacccat ttgtttacaa
    22861 caagtaataa gaaatgctaa tgaatcaaac atgtctataa acatgaaaga gaatataggt
    22921 ccaattaatg agaatttcaa tgcacctaca atatctaatt taaaagcaac tggtgctata
    22981 ctaggaggtg tcgagattat tgctgttggc aactccacaa atccaaatat aacagatatt
    23041 attgttgcaa ctactatact tatcaatatt ccacctttaa cttttttata ttctagtatt
    23101 gccattaaga taagagcaaa aagagctatt aaaactgttg gtgtaaaatc tgcaagtgaa
    23161 actatagtat ctggattagc tattataaca cccatatttt ttaaaccaac aaaagcaagg
    23221 aaaagaccta tacctgctga agatgctact gccaattctc taggaattgc gtctgcaatt
    23281 gtctttcgaa gacctgttac tgcgagtgta aagaagacac atccagatag aaaaactacc
    23341 ccaagacctg tttgccatgg gattcctgca cctataacca aagagtatgt gaagaatgca
    23401 tttaatccca taccaggagc tagagcaaat ggtgcatttc ctaaaatcgc aaatataagt
    23461 gtaccaatgg ctgtagctag tatggtaact gttataaggg cggctttatc cattccagct
    23521 tcagataata ttgctggatt tacgaaaact atgtatgcca ttgttaaaaa tgtagtaact
    23581 ccacctatta cctctgtttt aaggctagag ccacgttcgc taaatttaaa cattttgtct
    23641 aaaaagctta atgatgaatt atttccacct ggttgtacat tgttagtgtt tggtaccatt
    23701 tttacctcca aaaaacttta agatataaac aaaaaaatat atattcatat agatagaata
    23761 gaacatatat tcagagttga cattctattc atagaaaacc catttaaggt gagtttgtag
    23821 aaactattag accgtattac taatattata tgaacatttt ctatttgttt ttctgttgta
    23881 ttatatcgta atattgtatt atttacaata aatataataa aattattcgt ttttttgtcg
    23941 attttataaa aaattaaggt tatttattga aaaaaattac tttttccaat aattgaatat
    24001 gtatgaatat aatgtcaatt attctaactt gttttatact attaatggaa gtttattata
    24061 aatgagtttg tgatataatt ataaaagtac tgaatacatg gatatttcgt aaaaactttt
    24121 taatatatca aatatgtata ttaagttaat atattaaaaa aaataatatc aaaaataata
    24181 taatttatag tggaggggaa aatgactaaa attattaaag tgcaaaaacc taaatttaca
    24241 ggagaattag aaattattga aaatcttgaa gatatacttg aagatatatt taatgatgaa
    24301 aaaatattta ataaaattat agaaaatgaa gttataagtg atttagattc tgtaagagtt
    24361 agctttgaat cttgtatatt tagaaatgtg tcttttgaaa attgtaattt aaaaaagatt
    24421 gatttacttg atgtggtatt tgaaaactgc aatttatcaa atacattttt tgatggagga
    24481 agtatataca gagttgaatt taaaaatagt aaattgatag gagttagatt tgatgattgt
    24541 atacttaaaa acgttttgtt caaggatgtt ttaggtaagt attctaactt ttcattctct
    24601 aaatttaaga tagtttctat cttagattca aattttgaaa attctgtatt tcaagaagta
    24661 aaaggtgaca atctagtatt tgagtataca aatttaaaaa aagcaaactt taatggaact
    24721 aaactttctg gcatagattt tactactaat aatattgagg gaattgagat tggtatagat
    24781 gatattagag gagcaatttt tgatgtgtca caagcaattg atttaacgaa attgatggga
    24841 attatcataa aatgaaaaaa atattcataa aataaattgg gaaaacgtta acaatgtgtg
    24901 aatttttacc agattgacat ttttctgaaa ataaagtaag attatcttaa tattcaaaat
    24961 attttcaaag ggggtaattt agtgtgagta agcagatgag agatattttt atagttggtt
    25021 ttgctttatt ttctatgttc tttggtgcag gaaatcttat gtttcctcca tttttaggga
    25081 tggaatccgg caaagactgg ttaattcctc ttattggatt tgttgttgca gatgctggta
    25141 tagcaatgct tgttattata gcaacagcaa gatgtaaggg aagcatggat gatgtactta
    25201 ggagagctgg taaagggtta gcaagagtaa tgagtgtagc tgctctagca tgtttagcac
    25261 ttcttgtaat accaagaact tgcgcaacaa catatgaaat gggtattatg cctatatttg
    25321 gagaccatgg tccagtagct aaagctgtat tttcaataat cttctttggg ctaactttag
    25381 catttactat taggtcttct aaggttatag acataatagg taagtattta actccagcgt
    25441 tattattagt attatttgtt ttaatagtaa agggtataat ttctccagca ggacctatga
    25501 gtcctgagca tatgatagat aaaaatctat ttggtgaagg tatatcacaa ggttatcaaa
    25561 caatggacgc tctaggtgca gcatctatgg caactataat gttgatgtct ataatagcta
    25621 aaggatatac atcagataaa gaccaaatag gaatgactat taaagctggt tttgtagcct
    25681 gtgtatttct agcagtagta tatggtggtc ttacttattt aggtgcaaca gtttcaactt
    25741 tatatgatac tagtatacct caagcatctt tattagttga aataactagt atattgttat
    25801 atggtcaagt aggaaaggta attttaggtg taattgtggc acttgcctgt ctgactactt
    25861 ctacaggttt aacagcatca atatcaactt attttgaagg aataagtaag gcgagttata
    25921 aacaactggt tataggtata tgtgtagcta gtatgcttat atcaaattta ggtgttgatt
    25981 ctataatagc catatcagtt ccaatcctac aaactatata tcctgtttta ttagcaatag
    26041 ttgttatgga gttggctggt aaacatataa agaatgataa tgcttttaaa ggtgcagcat
    26101 atgttacatt agtgattagt ttattatcag ctataaatgg aatgacagga gctgttccat
    26161 ttatacaaag cttgccactt gcaggtttgg gctttaactg ggtaatacca gctatattgg
    26221 gtggaatagt tggtaacttt ataaaaagca acaaacaagt agcataataa tttgtaatta
    26281 atttaatttt ataatatatt aatttttagt actatgggta ggtttaatct aaacctaatc
    26341 tacccatagt actttttaga ttggattata atagcatgta tataattttt tataatataa
    26401 tttttctttg aagtatgata aaattagtaa tagtgataag aatgtacaaa tttaggaggt
    26461 tttaattaat gcttagaaaa ataacagcat ttatgctatc catatgttta attattggac
    26521 ttacaggttg tagtttactt gtaggcaaga aagataaaga gaaaattata gatgatttta
    26581 aagttgcagt ggtaactcaa ccattatctg aaaataaagt acaatacaat atggtggaag
    26641 agatggcaaa agaatatgag gaagagaata aaattgataa agacaaagat ggtcaaacta
    26701 aagttaaaca aactataaag catgttgtat tgccagagaa ttttacttct aatatagaca
    26761 gtgctattaa taagatagta aagttggctg acgataaaga agttcaggct attgtagttt
    26821 caactgacca agcagggctt ttacctgctt tacaaaaggt aaaggaaaag cgtccagaaa
    26881 taataactat ttctgcccct atgggagatg ataaaaacca attaagccaa tttgttgatg
    26941 tgaatctagg ggttagtgca gaggaaagag gaaaagtatt agctgaacgt tcaaaagaaa
    27001 tgggagcaaa agcttttatt cattatgcct ctacagatga tttgaaagat gttaatatag
    27061 ccaaaagatt agaaatgatt aaagagactt gcaaaaatat aggattgcca tttgtacaag
    27121 ttaatactcc aaatataaat actgaagaag acaaaaacaa agttaagcag tttttaaatg
    27181 aagatattga aaaacaagtt aaaaaatatg gaaaagatat aaatgtattt ggtgtaaatg
    27241 agtatatgga tgaagttata ttgactaagg ctttagaatt aaagtatata gttgcagagc
    27301 aaagcaatcc atcaccaata caaacatatc ctagtgttat gggtctaaaa atatctgaaa
    27361 aagatgctca aaattatgat aaaataaacg acatgataag tgaaaaggct aaggcttttg
    27421 gcatgtcaaa tagacttggt ggatatccta tgccaatgga tgcttttcta ccatcagtag
    27481 caatttatct tgctactgaa atggtgaaac aagatttaac acaagaagat gtatgtgacc
    27541 cagattattt agaggcgttt acagaattaa gatttggaat cggttcagaa tttactcctt
    27601 taacagaggt actttataat tatcaatcag taattttaag ccaattaatt tattaatatt
    27661 aaggaagtgt ctcaaaatga actttttagt ttatgaggca ctctttttct attaaatcaa
    27721 atatattttt atctttttaa caattaaaaa gaagcttatc cctatattga gatagcttcg
    27781 tttttaatat aaataagttt tattatttta taaaaaattt atagaaaaat aaaaaattat
    27841 aattatatat aaattttgat aaagtaaaga tgaattacta taggtttaaa ttatattatt
    27901 ttctattatt tttatgcctt tctcagttat tgatgagcct tttcttcctt tactagaaat
    27961 taagtatcca ttgcgtgtca aatattctag catatttctt acttcgtatt ctgtgacatt
    28021 atattccata aatttcatta actttgtcct ccccattggt ttcatgtgca atgattttag
    28081 gatagaaatg catatgtttt tgtcatattg gtttaaatca ttgaatatgg acatattact
    28141 tgacatatga ttattattta attttgaaga tatgttttga ggtaaatcat ttattgtaag
    28201 ataattggaa cccatgtaag ccatatattc aatacaattt ctcagttctc taatattccc
    28261 catccaagtg tatgaattta aagcttctaa aagactctta tcgagtttta tgtttttata
    28321 gggaagttct tttaaaaatg attctaaaag aagaggtata tcttctaatc tctttctaag
    28381 aggaggtaaa tctaaagtga acatacttat cctataaaat aaatccatcc taaatttatt
    28441 ttctataatt aatttctcta aatctttatt tgtggcagct aatattctca catcaattgg
    28501 aataatactt gtaccaccaa tttttctaat ttctttttct tgtaagactc ttaaaagttt
    28561 aacctgtaaa tcatgtggca tatctcctat ctcatctaaa aatatagtgc cagtgtgagc
    28621 taattcgaat aatccttttt ttccaccttt ttttgctcca gtaaaagaac catcttcata
    28681 tccaaatagt tcactttcaa gtaattcact tggtaatgaa gcacaattta ttgctacaaa
    28741 aggtttattt tttctatttg aatgattgtg tattgactga gtaaaggctt ctttacctgt
    28801 tcctgtttca cctgttatta atataggatt atctgtaaga gccatttttt ttgccttttt
    28861 aatacaatct tttataatag aactatttcc aataatatta ttaaatttat atttagctac
    28921 ataacctctt ttgacagaat cacttcttat tttttgttct aatatttcta tattgtttac
    28981 atctttcaat gtaattaagc aaccctctat atttttataa agataaaatg gttttttaga
    29041 aagtatgaat tttttatcta tttcgtctat gtatataatc atattatcga tatttaagtt
    29101 ctttgtaatt ttatctaaga aactatttgg catatattcc attaaggaag gtgattttat
    29161 aagtttttca tctagtccca acatattaag taaagactta tttacaaaag taaccttgtt
    29221 aaaggtgttg aaaaatatta gaccatcacc tatttcatca atggtcatgt aaagtatagt
    29281 ttttaattta gatatattat ctaatgatgt atttaagaaa tcatgactta gtgtctcttt
    29341 ggacaatttg tatagttttt ctataaattt ctcatttttt agttttaata ctactaataa
    29401 tgacatatat gtatctaatg agatttttct ccaacctaaa tcaacaatat tttttatgta
    29461 ttttggtata aatctaatct gacctggtgt tatagctgta tctaaatcat atatttcatc
    29521 acaatctgga tatgtcggta caaaatctat atgatttata ccaattttat atagataagt
    29581 agccatctca aatgctgaag ttttattggt tgtcataagt aacgattttg tacctggagg
    29641 tagtttcatc attttttcat atccaagttt tgaaagtgct ttcgttccat gaataatttc
    29701 aatatcttcc ttaaaatgtt ttattaaaaa attactagtt aaaggtgata gagaaagcac
    29761 tacatctccc tctaaatttt cttttattcc atcaagtata ttttgtgttt ctatgattat
    29821 ttcgtctcca aaaaagtttg ttaattcttc tttgtagtgg tcactattca atttatcatg
    29881 tgttataagg attaacttct ttttatccat tttatttctc ctaacaaaat agtatttatt
    29941 tttaaagtat ttaaagtata aggcaagtta tattatacaa caaatagtag tataaattta
    30001 tatatttgat taaataatag gtttttttag gattttatcc tataaaaacc tattttaaaa
    30061 ttatttttgc aagataagga aaatagcttt ttatattgta atgtatattt taaataatta
    30121 ataaaaaaat attatatttt taaacttgaa aagtaagtaa ttataagcta tttaatcact
    30181 ggaataaatt tacaataaaa aaataaatac aaaggcttta tcattaaggt attggcataa
    30241 gttttgctta ttaaacaagt atactaataa aattcattta aacaggaggg agaatttata
    30301 tgagtaaatt agaatcaaca acagaaaaag ttgaggtaaa atggtatggg tatgtagcat
    30361 taatattggg agcattattt ttttcaggaa tatttaaaga tgcaccagga ccattaaaag
    30421 tattggattt taacaatgta ttaggttctt ttggaacatt gggaacaatt aatgatggtg
    30481 taggtacatt agctgcaaac tttagaggtg atggaggtac tggccctcga gatggatggc
    30541 tatatgcatt gacattaata ccatcagtta tgtttgcact tggagtagtt agagttatag
    30601 accacttaga tggaatgaag gcagctcaaa agcttcttag tccactatta aagccattat
    30661 tagggttacc tggatttgca ggactaactt tgatagctag tttacagtct acagatgcag
    30721 ctgcatctat gactaaagaa cttaaagatg atgggtatat agatgaaaaa caaaaagctg
    30781 tattttgtgc atttcaattt tcaggtgcgt ctgcaattac gaatttcttt gcttctggag
    30841 cagcactatt tccatttata ggagatgtac caatatttat accacttgct ttaatattaa
    30901 ttatgaagtt tgttggggcg aacttactta gattatattt aaataaattt gacaaggggg
    30961 aagcttaaca tgagtgaggt agcaaaaaaa gaagtaaaag ttaaaaaagg aaatgtgata
    31021 gatgcgttta ttggaggagc tagaaatgga ttccaaataa gtacaaattc aatggctcca
    31081 aatgtcatct tcggttttgc tataatttct gtgttcaatt taacaggtct tttggatgta
    31141 atagggacaa tatttacacc tgtaatgagt atctttggac ttccaggtgt tgcagcaaca
    31201 gctataatga caatatttat atcaatggga ggagcatctg gagtaatcgc aggtttattt
    31261 acagcaggtc aaataagtca agcacatgtt gcaattctat tgccaatgtt attgctttca
    31321 ggagcgcaga tacaatttat ggggagactt ttaggaacag ctgagttaaa aactaaatat
    31381 tatccacata tgtttgttat agcaacttta aatggttgta ttgcaatgct tataatgaat
    31441 tatttcgtag tataggtaat tataataaag atttaatata aatggaaagt ttaaatttta
    31501 aggaggagct agattatgga aactaacaaa gactatattg agtatgtaca taaagtgtat
    31561 gattatctac acactatacc agaaaaagga tttgaagaat ataagacatc agagtttgtt
    31621 ttaaaagagc ttgaaaaaat ggggtttgaa aatattaata aaggaattgc aggaactggt
    31681 attatagtaa ctatagattc taaaaaagaa ggaccagtat ttgctataag agcagatatg
    31741 gatgcattgg aatttatcat agatggagaa aagaaaatga tacatgcttg tggtcatgat
    31801 ggtcatactt ctatgctttt aacagctgca aagttaataa aagagagaaa tttagtaaaa
    31861 agaggtaagt taaaaatact ttttcaacca ggtgaagaaa aattatatgg agcattaaga
    31921 gtaattgatt ctggtttgtt ggatgatgta gaagaaatgg tagggatgca tttaagacct
    31981 ggacaagatt gtaggttggg aaaggcgata cctgcaatgt accattgtgc tagctgtata
    32041 atggaattta cgattaaagg tatcacttgt catggttcta aaccacattt aggagtaaat
    32101 gcagtagatg ctgtctgttt agcagtgaat gcaataaatg caataagagt aaatccagct
    32161 ataccaaatt ctataaaagt aacaaatata tcagttaagg gagaaactta taataatata
    32221 ccagatgaag catttatggc tttagatata agggcagaaa gtaatgatat aatagaagaa
    32281 ttaaaagaaa aagcaataca tgctgtaaaa actgctgtaa gttctataaa tgcagaagct
    32341 gtactaattt ccaaagatgg agtaccagca gcagaatttg atgaagaact tgtaaacttg
    32401 gctgaagaaa ctataaaaga tgtattggga gctgatgcat ctataggtat atttaaaaat
    32461 tctggtggag aagatttcca ttattataca caaaaactaa aatgtaaaac tacatatatt
    32521 ggattaggag ctgatgctac accaggattt cataatccaa atgtaacatt tgatacgaaa
    32581 gctttagaat atggtgtaga tatatggtgt agattggttg aaaagagatt gggataacat
    32641 ccaaactaat aattctacat ttaaaattat aattatagaa gttatagaaa aagattgctt
    32701 atgttaatta gaaaataatt aatatgagca atcttatttt gatataatga aactgatttt
    32761 ggaatattga aaaaatatga tggaaaagta attatatttt aaatctattg gacaaaaaag
    32821 tgatattatt ataatattaa gaattgtaaa ataataccaa agtgcatcta gtaatagact
    32881 taacaattat aaaaatttta ttcttaggag ggaaaaaatg agtaagtata attttgacag
    32941 agtaatagat agagtaggaa cagattgtgt aaaatgggat tttagaacta attgttcaac
    33001 aaaagcacaa aaagatggtt tgcctttttg gattgctgat atggattttg aatgtgcaga
    33061 accaataata gaagcattac gtaaaaaagt tgaacataaa atatttggat atagttcaaa
    33121 tgatagtgat aaatacttta atgcagtttg tgattggtat aaaaggagat ttaactggga
    33181 aataaataga aaagatatta tttttagtcc tggtgttgta cctgctgttg ctattttagt
    33241 aagaatatta actaattcta atgaaggtgt aatagtccaa aaaccagtgt attacccatt
    33301 tgaagctaag ataaagagca ataataggga tgttgtaaac aatcctctga tatatgagaa
    33361 tggtacttat aggatggatt atgatgattt agaagaaaaa gctaagtgta gcaacaataa
    33421 agtactgata ctttgtagtc ctcacaaccc tgttggaaga gtttggagag aagatgaatt
    33481 aaaaaaggtt gtagaaatat gtaaaaaata tgacctatgg ataatagctg atgagataca
    33541 ttctgattta attagaaaag gatttaaaca tactccttta cagtcattat gcccagagta
    33601 caaggataaa atagttacat gtatagctcc aagtaaaaca tttaatctgg caggaatgca
    33661 gttgtctaat ataatagtga ataatgatga actaaaaaag aaatatcaag aagaggttac
    33721 agctgttgga gttgcaactt caccaaatcc ctttgctatt gtagctacaa tagcagcata
    33781 taatgaaagt gaagactggc ttaatgaatt aaatgattac ttagataata atatacaatt
    33841 tattgatgaa tacttaaaag aaaacctacc aaaagtaaaa cttgtttatc cagaaggaac
    33901 atatctagca tggttagatt ttactgctta tggattaaat gaagtagaac ttgaagattt
    33961 aatgtttaaa aaagctaatg tattatttga tgaaggttat atatttggaa aagaaggaat
    34021 aggatttgaa agaataaatg tagcttgtcc acagtcttta ttaaaagaat gtatggacag
    34081 attaaagact atatttgaaa atttataaag tataggtaaa aatttataaa gtgtttaaaa
    34141 ataaaaaaat aataaacttg acaaatttta actaatcact tatcatacta ttatgaataa
    34201 atagaaaaca taagagagct aaattttatt gaattaaact cttaaagact ttgaaaggaa
    34261 gagtagttat agaatgtaat taaagcgagt tggtgatggt gtgagaccaa tatgaagtct
    34321 ataatgaaga acatcctgga gttgctaacc gaaattttaa aagagtaggc ttagtcggaa
    34381 ccaaaccgtt atcatattgg ggtgtatcga gtaatatctg tacattgtga gctgggtttg
    34441 aatttatttc aaactaatca gggtggtacc gcggaaaagc aacctttcgt cccttttata
    34501 tagggatgaa gggttttttt aatggaaaaa tatataaata tagggagtga atgatatgag
    34561 cacaataata ccaaaggatt ataaaagtag tttgaacgta attgatacac aaatagctat
    34621 aaaaaaatta aaagattttt ttgaaatgag actaagtaat gaattaaatc ttataagagt
    34681 ttcttctccg ttatttgtat tgccagaaac aggtgcaaat gataatttaa atggagaaaa
    34741 ggctgtaagc tttgatatac catttatgaa taaaaatgca gaaattgttc aatcacttgc
    34801 aaaatggaaa agattagccc ttaaaaaata tgggtttgaa gttggtagtg gtttatatac
    34861 agatatgaat gcaataagaa aaaatgaaga attagacaat atacattctc tttatgtaga
    34921 ccaatgggat tgggaattgg ttatagataa aagtagtaga aatgaaaaga ctctaaaaga
    34981 tgttgtaaaa agattgtatg gagtatttaa agatactgaa atttttgtat gtagtatgta
    35041 tgaaggtata aaagaaatat taccagaaga aataactttt ataacatcac aagagttaga
    35101 agatatgtat ccagaattat caccaaagga aagagaagat aaaattgtaa aagagaagaa
    35161 agcagtattt ataactcaaa taggaaaaac attaatatca ggagaaaaac atgatggaag
    35221 aagccctgat tatgatgatt gggaattgaa tggggatata ttattttaca atcctgtttt
    35281 agattcagca ttagaattat cttcaatggg aattagagtt gatgaagaat ctcttgatag
    35341 acaattgaaa cttgctggat gtgaagagag aaaagagttt gactatcata agatgctttt
    35401 aaatggcgaa cttccgtata caattggtgg aggaattggt cagtcaagaa tatgtatgta
    35461 tttcttacaa aaagctcata taggagaagt acaagttgga gtatggccac aggatatgat
    35521 tcaaaattgt agtagtgcag gaattgaatt attataattt aaatataaac taattgataa
    35581 aatttatatc taatatgttc atcaaattaa ttatatcggt tataatgtag aataacctat
    35641 aattataaga ggtgataaat atggagtttt taaaaataat cattaatata gttttagata
    35701 ttttaaaaaa aattttggtc agatttaaaa atgctaaatt tggtttggtt tttgtatttg
    35761 atttacttaa actacctgat tttatgacag ataaaagaat caatatagtt gataaaataa
    35821 aggtaatttc tgtattaatt tttactatat cctactttgt atctggggtt gatataattc
    35881 cagagatgat tgcaggggca tttggtttta tagatgatgc tatagtttta atttggagta
    35941 taggtatagt gaatgaagaa attaataagt atagagttat cgcaaaaaaa gataaacatt
    36001 caaatataat tgaaaatgta gaattttcta taaaagatga agaagaataa caatttatat
    36061 atgttattct tttttttatt aacaaaaaat ggttaaattg ttgacggaga ggtaaaactc
    36121 tattatcata ataagtggat atccaatatt taactaagta ttcaatgtgc aagaatgctt
    36181 aatttaaaaa agttatggag ggtaaatatt atgaagaaaa aaataggttt agtgcccaaa
    36241 ctaatcatcg gtatcatagt cggtatttta atcggaagtt atgcaccaga aataatagta
    36301 caaatattag taacagttag tactttattc tcagcattcc taaaatttgt tataccattt
    36361 ataattatag gttttgtaac agcaggtata gctgatttag caacaggtgc aggaaagtta
    36421 ttggggataa ctacgggaat agcatatggt tctaccttaa tagcaggatt attatcattt
    36481 gcagtatcta cattaatctt cccaaatttt attgatgcaa gtgttgcaag tcaaattgga
    36541 gacccagagg caggaatgtt agctccaata ttcacaattc cattagagcc tatggtagat
    36601 gtaacagctg caatcgtatt tgcatttgta atgggacttg gaatatcagc tttaagaaat
    36661 catggaaaag gagagacttt atttaatttc ttccaagaat ttcaaggaat cgtaacgaaa
    36721 acgttgtcaa cagtgattat acctttatta cctttataca tagcaggaac ttttgcaaat
    36781 ataactatag caggggaagt atggacaata ttaggggtat tctggaaagt atacttagta
    36841 gtaatacctt tacattttgt atatatggca tgtcaattca cagcagcagg tgtattttca
    36901 ggaaaaaatc cagtaagaat gttaaaaaat caagtacctg gatatttaac agctatagga
    36961 actcaatctt cagcagcaac tataccagtt aatgttggtt gtgcagaaaa aaatggagta
    37021 agtaagcaaa taagagaatt tgttgtacct ctttgtgcaa caatacattt atcaggtagt
    37081 atgatatcaa taacaggatt tacaactgca gttttaatga tgaatggtat gccacatgga
    37141 ataggtgtat tattccctta tattgcaatg ttaggtatag caatggttgc agcaccagga
    37201 gcaccaggtg gggctataat gagtgcactt cctttcctac caatggttgg aataccatca
    37261 gatggtgggc ttgcaagttt aatgatagct ttatacttaa ctcaagacag ttttggtaca
    37321 gcatgtaatg tatcaggaga taatgcaata gcagtagtag tagataaaat aaatgatgga
    37381 atgagtaaaa aaggaaataa agaagagcaa agtgcttagt tttttaataa tcaaaaatga
    37441 gttatctcaa atagagatag ctcatttttt atggtataaa aaattataaa ataaagtgat
    37501 ttttttattt aaaaattgct ttaagagatg atattaataa tttattttca ttaggtttta
    37561 atatacatac tctaaagaaa tactcatcta gaccttcaaa tgaacaacaa tctcttatta
    37621 ttattttttg tggaagcaat tgttctcgaa gagatttagc agtcaattcc tttgtcttga
    37681 ttttacacaa tatgaaattg cctttagtat tgtatatatc taagcttttt atattcttaa
    37741 gctctttaag caggtaatct ctttcagtgt tcattaagga aatagtattt gatataaaat
    37801 ctaaatcact aaacatgatt tcacccattt tagaagctat tatgtttata ttccataaat
    37861 ctagattttt atttatttca tttttgacat tagtgttaga tataagacca tatccaagcc
    37921 ttattccagg cgttgaaaaa aattttgatg tacctcttat aacgaataaa ttagaataat
    37981 catcaactaa ttgagtacaa gagtatgtat ctgtatcagt aaactctaca taagtctcat
    38041 caatcattaa aaatgagtct gtatttttta aaatttctct cacttctact ttagtaaatg
    38101 caaatccagt tggattacta ggattacaga ttactaccaa atcataatct ttagcattga
    38161 tagtttttat aagattttct aaatttatat gaaaattatc ttcttctttt gcaaagtatt
    38221 tttctataga acaattaatt ttagataact ctttttcata ctctgaatag gctggagaga
    38281 gtaaaagagc ctgtttaggg ttaattgtat gtataaatga tgaaattagt tctgtagctc
    38341 cactgccaag tactatatta tctatagaac atttgcagta attggatata gaagttttta
    38401 agtctatgta atcagggtca ggatacatag ataccatatc tatattgttt acaatgtatt
    38461 gtttggctaa acttgatgta ccaaaaggat ttatatttga gctaaaatcc ataaattctt
    38521 cctttgaaaa gccatactta ctagataaac tatataaatt agctccatgg tttgtgctca
    38581 taaaagtacc tccaaaaata aaattatata atcgataaaa ataactgatt aatatatgta
    38641 catatagatt ataatacaaa ggaatcgtta ttccaaattt ttaatggaaa aagcaaaaaa
    38701 gtatggataa gctgttaatt taggtttaaa aatgatgaaa aagattttaa ttgatatttt
    38761 ggtatgctat aatatataag ttaatagaag gaaagcggga ggatacaaaa tgtacaaagt
    38821 tacaggaaaa atgttgacag aagaacaaat aaaagaaaaa gtttatgaat taggaaaaaa
    38881 gatagaagaa gactttaaag gcgaagattt actagtggta ggtatactta aaggagctag
    38941 tgtatttgtt tcagatttaa taagatgtat agatttggat gtaaatatag attttatgag
    39001 tgttacaagt tatggaaact caacagagtc ttctggaaca gttaaaatat taaaagattt
    39061 agatgtagat attgaaggaa agaatgtgtt gattgtagag gatataatag attctggttt
    39121 aacattaagt aatctagttg cagctttaaa aactagaaat ccaaaatctt taaaactatg
    39181 tactctactt gacaaacctc agagaagaaa agctaatata cctgtagact atgttggatt
    39241 tgttatagaa gacaaattta ttgttggtta tggaatagac tatgctgaaa agtatagaaa
    39301 tttaccttat ataggtatag ttgaggatgt agaatagatt taaatgtgaa tcaaaagcac
    39361 taatttctaa gggagttagt gctttttagt taattatata aaattttagt aaaggagaca
    39421 tctatatgga tattcagtta aatatattat tatttttcca aaatttaaga aatccaattt
    39481 tgaactttat atttcttgtc tttacaataa gcacagaagc accgttatta atattaatta
    39541 caacaattat atactggtgt ataaataaaa aatgtggaca gaaaatactg tttgctataa
    39601 ttggaaattt tgttgtaaat ttaggcatca aagagtttgt aaaagctccc agaccaatag
    39661 gaataaaagg tcttgaatca ttgagagttt ctactgctgg tggttattct tttccaagtg
    39721 ctcatactca aactgcaaca acattttggg ttagtattat gactatattt aaaaagagat
    39781 atcttcattt aataggtgca gttatggttt taggagtagg attgtctagg ctgtatttag
    39841 ctgttcattg gccaatagat gtgatagcgg gttggatatt aggaatattt tttacagttg
    39901 tatttgtaaa aatatttgac tatattgatg ataataaaaa ttatatttta cttgtagttt
    39961 tacttatacc atttataata gtggctatat ttctaaatag ccctgaatat tttgaaaaat
    40021 ttggtataat agtaggattt gtatttggat atatggttga ggatagattt gttaaattta
    40081 atacagataa taataacaaa aaaataaatt ttagtaataa aaataagggg agtaaaaata
    40141 taattttttc aagaatatgt aggtttttgg ttgggatagt aacaatagga atgttatata
    40201 ttggcattaa gttgtttatt tcaatgttaa tagtcacttt aaatataagt gactctacta
    40261 tgagtataat ttttatgaat tttattaaga atacagtagt tgttttttat ggaatagcag
    40321 gagctccagc attatttaaa cttttaaaat taaattgatt ttaaggtata gagtcaatag
    40381 tttaaattaa aaaaattaag ggtagaaaag agtgattatt tgaagaaggt agtaataata
    40441 ggtggtggac cagcagggat gatagccgca tcaactgcat gtgagaaagg ctatgatgta
    40501 acattaattg agaaaaatca taaattagga aaaaaacttg caataacagg aaaaggtaga
    40561 tgtaatatta ctaacgcttg tgaaatagag gaattaatag aaaatgtacc tacaaatgga
    40621 aaatttcttt atagtgcttt ttatactttt acaaatgatg atgtaataag tatgtttaat
    40681 aatcttggag taaagactaa aacagaaaga ggaaaaaggg tttttccaga gagtgataaa
    40741 gcatttgata ttgtaaatgc tcttgaaaga caacttaaaa gtaagaaagt aaatatatta
    40801 ttaaattcga aagtagaaaa aataatatct aaaaataata aaattgaaaa agtaatttta
    40861 aacgataaaa aagaaattaa gtgtgattca gttgtagtag caactggtgg attaagttat
    40921 ccacttactg gttctactgg tgatggatat aaatttgcaa tttcacaggg gcacacaatt
    40981 atagatacaa aaccatcttt aattggtata gaagtacaag aaagttttac aaaagattta
    41041 gaaaaattat cattgagaaa tgttgaaata agggtgttta atagcaaaca aaagaaagtt
    41101 tatagtgatt ttggagaact tgaatttact aaatttggtt tagatggacc tataatcaag
    41161 tctgcaagtt gtagaatgaa agatacaagg aaagaaaatt acactatatt attagattta
    41221 aaacctgcat tagatgagga aaaattggat aaaagagttc aaaaagattt tcagaagtat
    41281 acaaataaaa aatttgaaaa agcattagat gatttacttc caaaaaaact aatacctata
    41341 ataataaact taagtgaaat taatccaaat acggttgttc accaaatttc tagagagcag
    41401 agaaaaaact tagtccattt attaaaaaat ttaaagttta cagtaaagag atacagacct
    41461 attgaagaag ctataataac ttctggtggt gtaaaagtaa acgaaataaa ttcaagtaca
    41521 atggaatcaa aattagtaga aggtttattt tttgctggag aagtaataga tatagatgca
    41581 tatacaggtg gattcaattt gcaaatagct ttttctactg gatatttggc aggttttaat
    41641 tgctaaaaat tacctgaatt aaaaatgttt aaaatcacat aatattatca gcaacacaaa
    41701 ataaattaaa cagaaggaag gtaatcaaca tggcaagtaa caataacaac aacagaacag
    41761 tagtaccagg agcaaaagag gctttaaacc aaatgaaatt agaaatagct aatgaacttg
    41821 gtatgagtaa ttatcaacaa gttgataaag gaaaccttac tgcaagagaa aatggttatg
    41881 taggtggata catgactaaa aaattagttg aaatggctga acaacaaatg gctggaaaaa
    41941 gcaacagata gttataaata attatttata actattggct attagtttag ctagagctat
    42001 ctcaaatata gaaagtaatt tctaaattga gatagctttt ttttattaaa ttattaaata
    42061 gatatatttt tatgtaataa attttatgta tttggataaa ataatacaaa tgaatatgtt
    42121 acataaggag tgatgtaaaa tgagtagtgt aaattttgag gatttaaaaa acaaatttat
    42181 taatagtgac ttagatgaaa aaataagaat atatacaaca acagaaggtt tatcagtaga
    42241 acaatttaaa gagctactaa aatattatcc aatacaacat ttatctaaac tagaaaaagc
    42301 acttggatag cagtatttaa tccaaaatta aaaaggcaat ttatttaata ttaaaaatat
    42361 tttttattaa ataaattgcc tttttataat aggtttaaat tattatgctt ttgatatata
    42421 attatagatt ctctcatttc caagttcaat agacccagta ttaataagag taactattcc
    42481 ttctatatct ctagcagtta agtatttata tggaattaat aaattataac cagtattact
    42541 tagtaagttt tttaattggg ttatttgaga gatattgaaa cattttgcag ttttagtaga
    42601 tttttttctt aagttagata aattttcatt ttgaatattt attaaagttt ctatatagtt
    42661 tctataagat atcttaaagt ttgtctcatt gactattttt tcattaagta tactactgat
    42721 aaaatcttga gacaatatat tatctgcaaa tttatctgct gttaattttc cagatgttat
    42781 gcctttttga tattttctaa gaattttttt agtatagcag tatattttat ttctcgtttc
    42841 taaatcgagt tgttctattt gcacaaaacc acttccttct aattataaaa atatttatta
    42901 aaaatctata cttaactaat aaagcttcaa taacttattt acaataaata ctaaatcata
    42961 aaatatttgt tattttttat tattaccaag tataaaaaat attataattg taaaacttac
    43021 aaatatatgt aaaatattta ggagtgatga aaatgttaaa tgggataata aagctttttt
    43081 attctgaaat tgtaaaaaca aagattaata acttagattc aagtggatat tctttaagag
    43141 atgaatgtaa agaaatcaga aatataactc taaagataga tagtgtattt tttaagcttt
    43201 taaagttagc ttttggttca atattgctta tggtagcttt taatttaaac atggttttag
    43261 gtataggagt gtttttagtt ggtgtagttt atatactata taaaagaaat atggaagaac
    43321 aagtaaaaga gcatataaat aatgtgaaaa ataatatcga catctctaaa ataactttta
    43381 tggatgaaaa agggagaaca ggtctaaatg cattaattac attacttctt ataggattat
    43441 tgacaggatt taactggata ttagttgcta gttttgtcgt tgtttttgtt tttactataa
    43501 agaatgtatg ttaaaatact gataaatagt ttaatatata gggggagaaa ttgagtatga
    43561 ctaatggcag ttataaaatg aagaatttag tggaaatatc cgctatggtg actgaatcta
    43621 cagatttttt taatataaaa gatgacataa tagaaaaaat gttagaagtt gttcacccta
    43681 caaaggcatg tgtgaatcta ttttataaaa atgattctaa atatgcctac ttagtatgtt
    43741 cgcaaacctt agaatatgta cctcaaattt ttccaataaa tagtcttaaa ggtgcaaaaa
    43801 ttgattttga cacatatcca gagtatatac atgaggctgt aaatgaaaaa aaaataatat
    43861 atgtggaaaa tgtatttgaa gattctagag cagaaggtga acgagattta gcaaaagctg
    43921 aaggttatat tgggagaata gtttttcctt ttataataaa taacgtagtt gttggattta
    43981 tgacttgttt tttaaaagag gatgattata taacagaaca agatatagat tttatatcat
    44041 ctgttgcatc actcttaagt ttatcaatag aaataactaa taaaaataat aatgtacaaa
    44101 ttttaattga taaactaaga ggctcaataa gtgccataaa tgaagctact aaaaaactat
    44161 accttaataa gagtattgat ggatttttgg aaaatttaag taaacaagcg tgtaatatta
    44221 ctaatagtaa agaagcttta ataattataa atagtcatca taataaggat gctatagtta
    44281 gttgttataa tgttgagcaa aaaaagaaaa caaatttata tcctatgatt gatatgtttt
    44341 taaagaaaga gtcattgggg gggtatttaa ataatttaaa accatgctca aaaaagggaa
    44401 taaatttgga aagttatata tattacaaac ttcaggataa aaatgagact ataggatgta
    44461 tagtttgtgc aaatagcaaa aactatacta gtgatgattt aaatattctt agtatattgt
    44521 ccaaacaagt ttctgttggt atgcaattat atgaacataa tgaaaaggaa gtaaaacaca
    44581 aagttcttga aaacgagttg aacatattaa ataaacaaca acagcttatt atggataaag
    44641 gtaaaatgga ttgtaatgat gagaaagaac tttattttta ccataaacca gcaagggtag
    44701 taggtggaga tttttattat gctacaaaag tggatgatga acatatagtt tatattgttg
    44761 ctgatgtaat gggacatgga atggtatcaa attatgttgt tgcaatgata aaaggtgctt
    44821 ttaaagtatt atgcaatcaa tacaatacac caagagaaat aatgacaaat ttaaatagga
    44881 tgttatatga tgaatttgac aagatgggag tatttacaac ttgtttgata ggtattatag
    44941 atactaaaga aaatatgatt actgtgtcta atgcaggtca ctatagtcct gtagttgtaa
    45001 agaaagatgg cacaatagaa aataatttaa attgtaaaaa gggcatacct attggaataa
    45061 tggaagatgc tacttatgaa aataatactc tttcaatgga agattatgca atggtatgta
    45121 tgtacactga tggaatttta gagataaaaa attcatcaaa agaagagtat ggtataaaca
    45181 gattagaaaa ctttctaaaa gaaaatttta gattaaatca acagttaata gtagaaaatc
    45241 taaaattgga tttaaagaac ttctcatcaa aagataatta tgatgatgat attttaatag
    45301 ttatgttaaa ggataggtag attgattatg gattcaaacg ataaaaaagg acttaaaagt
    45361 ccagagatta taataataaa tggaagtcca agaattaata aaaattgcag ttttatagca
    45421 aatgaagtaa aagctatgct agaagagtgt ggattaagtt gtaaaatatt taatatctac
    45481 aatatggata ttgaatattg cacagcatgt ggattttgtg aaaaaacagg gtattgcaag
    45541 tttaatgatg atatgaagcc attatataaa atgtttgatg attcaaaagg aactatagta
    45601 ataagtcctg tacattttga ttcaatatca gctaaattaa agactgttgt tgatagaact
    45661 caagctatat atgcaagtaa atatgtatta aataaacctt caattgatag aagtaagaaa
    45721 cggataggaa tgtatattgc agtgggaggg agtaaatcat atgattcaca gtttaaaggt
    45781 ggacagattg ttatggattt tttctttaag agtataaata ctaaactttt acacaatata
    45841 tatttaaaca atacagatga tgtatcttat atagataatc aagaatttaa agatataata
    45901 tataaaaatt taaagatata tattgattca atataatttg attttgtagg taatattatg
    45961 tataattgta ttgcaataat ttaaataatt aaaaggaggg aatttcaatg aaattaccaa
    46021 tagcattatc taataaacat gttcatttga gtcaagctga tatagacgta ttatttggag
    46081 caggtcatga gttaactaaa tttaaaccat tatctcaacc agggcaatat gcctgtgaag
    46141 aaaaagtgga tttagtagga ccaaaaggaa ctttaaaagg agttagagta ctaggaccag
    46201 ctagagctca tactcaagtt gaaatatctt tagcagatgg tttcccatta ggagtaaaag
    46261 caccaataaa agaatctggt gatatagctg gaactccagg tgttaaatta gtaggacctg
    46321 ctggagaagt tgaaatgaaa gaaggagtta tagttgcttc tagacatata catatgagca
    46381 atgaagatgc tgctaaattt ggtgtaactg ataagcaaat agtaaaagtt aaaacatctg
    46441 gaccaagagc attagtattt gaaaatgtat tagtaagagc tagtgacagc tttaatctag
    46501 aaatgcatgt tgatatggaa gagggaaatg cagcaggcgt taaaaatgga gatttagtag
    46561 aattaatagt tgattaatat tataaataga ctttatgcta gtagatattt tatttgctag
    46621 catattttta aatgtaataa atttctatag gataaattta atcaattaga ttaatttata
    46681 aaataaaggg gtattataaa aaatgtaata aaaacttaca aaaatatgat gtaatatggt
    46741 aaaattatat atataaaaat ttacatgtaa taaggataag cattttactt tttatactaa
    46801 tatgaacaaa tagataaaaa agtttgaaaa atctaactta atttattata tattgtatac
    46861 aaaattatga aaaaaactta acatatttaa ttttaaaaaa aatctactta aatatgtaat
    46921 taatttacaa ttttcaaagg aattttatct aatctgtagt attatattag aagatagagt
    46981 atttgcgcga ctatatgtgt gtttatagtt ttgttgtgta aattatatgt aaatataaaa
    47041 aaatagactt gttataaaca agtacaattg tagctatcaa ggaggataca tattatggct
    47101 aagtttatga aaacacttga tggaaataca gctgcagctc atgttgccta tgcgtttaca
    47161 gatgtagcag ctatatatcc aatcacacca tcttcaacta tggctgaagt agttgatgag
    47221 tgggcatcac aaggaagaaa aaatatattt ggacaaacag ttaatgttgt tgaaatgcag
    47281 tcagaagcag gtgcatcagg aacattccac ggttctttac aaggaggagc tttaacttct
    47341 acttttacag catctcaagg tttattatta atgataccta acatgtataa agttgcagga
    47401 gagttgttac caggagtatt ccatgtaagt gctcgtgctt tagcatctca agctttatca
    47461 atatttgggg atcaccaaga cgttatggct gctagacaaa ctggatgtgt attattagct
    47521 tctggttcag ttcaagaagt agctgatata gcacctgttg cacatttagc tgcaatagaa
    47581 ggtagattac catttataca tttctttgat ggattcagaa cttcacatga aatccaaaaa
    47641 gttgaattac tagaaaatga agattatgca agtttattaa actttgaagc agttcaagca
    47701 tttagagata atgctttatc tccaaatcat ccagttgctc gtggtactgc tcaaaaccca
    47761 gatatatatt tccaaactag agaagcttct aataaatact atcaaaatat agtaggtata
    47821 gttgaaaaat acatggaaaa aatgagtaat ttaacaggta gaaaacatag tttatttgat
    47881 tactatggag cagaagatgc taaatacgta ttaatagcta tgggttcagt aacagaaaca
    47941 atagaagaaa ctatagatta cttaaatgct aagggagaaa aatatggttt agttaaagtt
    48001 catttatata gaccattctc aatgaaacat ttcttagatg ctatgccatc tactgttgaa
    48061 agaatatgtg tacttgatag aactaaagag ccaggttcaa ctggtgaacc attatactta
    48121 gatgtacgtg atgtattcta tggaaaagaa aatgctccta tgataatagg tggaagatac
    48181 ggattaggtt caaaagatac tactccttca gatataaaaa ctgtttttga taacttagtt
    48241 tcagaacaac ctaaaaatgg atttacagta ggtatagttg atgatgtaac taatacttct
    48301 ttaactccat ctgagccaat aaaaatagct tctaaaggaa ctataagatg taagttctgg
    48361 ggattaggtt ctgacggtac tgttggagct aataaacaag ctatcaaaat aatcggtgac
    48421 catactgaaa aatatgctca agcttacttt gattatgact ctaaaaaatc tggtggtata
    48481 actatgtctc acttaagatt tggtgatact ccaataagag ctacttattt aatagatgaa
    48541 gctgattata ttgcctgtca taaacaatca tatgtttatc aatatgattt attaaaaggt
    48601 cttaaaaaag gtggtacatt tgtacttaac actatatggg accaagcagg acttgaagaa
    48661 catttaccag ctcatatgaa acaatatata gctaaaaatg atataaaatt ctatacagtt
    48721 aacgctgtta aactaggaca agaaataggt cttggaaaca gaataaacat gataatgcaa
    48781 tctgcattct ttaaattagc tgaaataata ccagaagaag atgctgttaa atacttaaaa
    48841 gattctatag ttaaagctta tggtaaaaaa ggtgaaaaaa tagttaacat gaactatgct
    48901 gctgttgatg caggaataaa tgctttagtt aaagttgaag ttccagcttc ttgggaaaat
    48961 gctgttgatg cagataaagg agaagttaaa gaaccagaat ttataaaaaa tatactaaga
    49021 ccaatgactg cacaagaagg aaacaactta ccagtaagta cattcaatgg tatagaagat
    49081 ggaacattcc cttgtggtac tgcagcttat gaaaaacgtg gtatagctgt tgatgttcct
    49141 gaatggataa tagataactg tattcaatgt aaccaatgtt cttttatatg tcctcattca
    49201 tgtataagac cagtattagt tactgaagaa gaattagcta atgctccaga aggatttgaa
    49261 gctaaaaaag cattaggtaa aggattagaa ggattaaaat atagaatgca acttagtcca
    49321 cttgactgta caggatgtgg aaactgtgct gacatatgtc cagctaaaga aaaagcttta
    49381 gttatgaagc caatagatac tcaacttgat acagagttag ataattgggc atttgcagta
    49441 aatcctgatg aggtagctcc aaaaggtgat gttatgcctg caaacactgt taaaggaagt
    49501 caatttagac aaccattaat ggagttttca ggagcatgtg ctggatgtgg agaaactgca
    49561 tacattaaag tagttacaca attatatgga gatagaatga tgatagctaa tgctactgga
    49621 tgttcttcta tatggggagc ttctgcacca tcaattcctt atacttgtaa ccatgaaggt
    49681 aaaggtccat cttgggcaaa ctctttattc gaggataatg ctgaatatgg atttggtatg
    49741 tacacagctg ttaagcaaat aagaaataaa atagtagatg ctatgacaga gttagtttct
    49801 atggatatct gtgaagatgc taaagcggta tttacagagt ggttagattc tagaaatgat
    49861 ggagaagctt ctaaagtagc aagtgctaag gttgttgaat tattagaaaa accagcttgt
    49921 gattgtacag atgaaaaagc taaagagtta gtaaaagcta taaaagatag aaaagattat
    49981 ctagttaaga gatctcaatg gatactaggt ggagacggtt gggcatatga tatcggttac
    50041 ggtggattag accatgttct tgcatctggt gaagatgtaa acgtacttgt atttgataca
    50101 gaagtatatt caaatacagg aggtcaagct tctaaagcta ctccagctgc tgctatggct
    50161 aagtttgctg cttcaggtaa aaaatctaga aagaaagatt taggaatgat ggctatgaca
    50221 tatggaaacg tatatgtagc tcaagttgct atgggtgctg ataaaaacca atttatcaaa
    50281 gccgttatag aagctgaaaa acatgatggg ccatctttaa taatagctta tgctccatgt
    50341 ataaaccatg gattaaaaga aggtatggga agaactgtag ctaacgaagc acaagctgtt
    50401 gcttgcggat actggcattt atacagattc aatccagaag taaaagctga aggtaaaaac
    50461 ccattcactt tagattcaaa agaaccaact gcaagcttca aagatttcat acttgcacaa
    50521 gtaagatatt ctgctatagc taaacaattc ccagaggaag ctgatggatt atttgctaaa
    50581 gctgaagctg atgctaaaga aagatatgaa ggatacaaaa aattagctga ataatattaa
    50641 agtattataa tgcttatata gaattgataa aagagagtgt ctcaaagtga gctttttagt
    50701 tcatgaggca ctctttttgt atgaaatcaa atatatttta atcatttcaa caatgaaaaa
    50761 ggccttatct ctattttgag acagcctttt tttatgaaga tattaagatc ctgtttttac
    50821 ctattaaata tctttttaag ttttccattt tcatcttgcc aatacttttt atatattgct
    50881 ctacacacta aaattaagag aacaaataat atttatagta tgtatatttg gatttgataa
    50941 ttttaaaata gatacaaaag agtatctcat ttgtgttttt tatcacttag agataatctt
    51001 ttgatatgta tggaaaaaga ttattttatc ctacaaagat ttgtgtccaa taaattgaac
    51061 caccactttt ttgtgctact ccaacaccta ttttactgaa atttggattc attatatttt
    51121 ttctgtgacc ttcagaattc atccatgcat ttacaacttc tttaggagtt ttttgaccca
    51181 tagctatatt ttcacctgct gtcttatagc ttattccaaa ttttttcaac atgtcaaatg
    51241 gagaaccata agttggagaa ttgtgtgaaa aatagttgtt atcaatcata tcttgagatt
    51301 tttttgtagc aacatttgat atagaagaat caagagtaag aggatttaat ccagctttag
    51361 ctctttctat atttactaag tcaacaactt ctttttggta agctgaaaaa ctttcacttg
    51421 tagagcctga gttgttatta tcatcaggtt tgttagtaga gtctgaatta ttgttgtctt
    51481 caggtttatc agtagagcct gaattattgt tgtcttcagg tttattagac tcaggtttat
    51541 tattatcagg tttattagta gagcctgaat tattgttgtc ttcaggttta ttagactcag
    51601 gtttattgtt accaggctta ttagtagagt ctgaattatt gttgtcctca ggtttattag
    51661 tgttgttgca attcttgtca ttatgattct tatccttaca agagttatct ttatcaggct
    51721 taagttctgg ttttacagaa caatttggtt ttgcagaaaa cttgtattta gtattactat
    51781 atactaaact tttgttactt atatttacat tattttcaag tgatgaagca cttgcagtaa
    51841 cagcacttga agctgttgct aaagttaaca ctcctaaagc taatatagtt tttaattttg
    51901 ttggtatatt tcttctcatc attaaacacc tcttaatcta aaaattctaa aaatgttact
    51961 gatttgtaac ctttagtgta gggggttacc cgtgaatcta tactaacata agattaagac
    52021 tttttttact gtaaagatat gtaaaaaaga tatatatgga ataaataggt atatttcagt
    52081 gtgtttgaca atttgtatta aaagcctgta tagtatggaa ttacttagtt agagaaaata
    52141 atatttttat aataattcca taacgtaaat ttatagttat gataaatttt tttttatttg
    52201 gttaaattta ttcagtagat gctttcgtat tagcaacaaa ttataattat ttaaatcttt
    52261 aagaaataaa aagggtctgt ctcaaaatag agataaggcc ttttttattg tttaaatgat
    52321 aggcatatgt tatttcatat aaaaagagtg tctcattaag taaaaagttc actttgagac
    52381 accacctttc atattatgaa ttttaatttg ttttatatta atacattagt aatcctaatg
    52441 taattacaat aatttctgct attagtgaac caactgcaac tacaatgaaa gtttctttaa
    52501 atccagtttt atgtgttaac ttagataagc ttaagaatgt aagaaaaaca ccactttgtg
    52561 gaactatagt tagtatattt gaagctattg tagcaacacg gtgaattaat tctggattta
    52621 gaccagtact taaataataa tctgcaaagt ttggcattac tattcctaat gcaccagaag
    52681 aggaccctgt tattgctgac attgttgaag tcaaaacagt aagacttata agtggactac
    52741 ctggtattga cattataagt ttgctaaata catcaaaacc aggtgcagcc attattactg
    52801 ctccaaatgc aactgcagaa gatgtagcaa atataggacc tatagaacca ctagcaccta
    52861 tgctcaatgt ctgtatctta gatgatagaa atttatggaa taaaaaagca gataaaagaa
    52921 ttgcaactat taaagctatg taaattacat tttttttcat aaattctgaa ccaaaagtac
    52981 ttccagttat agctataatt acgagtgcta atagaggaaa aatacttgca aaaaatcctg
    53041 gtaattctct atctaaagat tcttcttcta attctgaagt ataagttgca taagtttcac
    53101 cttttctaat acttttgttt agagcatatt tcatatagac aagtccaaac gtagcacaac
    53161 ctatactacc tacaatactt ggtatagtag ctgcagtaag agacgtattt agatattgaa
    53221 taggtataac attttgaatg gctggtgttc caggaattat agtcatagta attgttgcaa
    53281 taccaagcca aagtggtatc tgaataaggt tccaagaaat atcaagtttt ttaaatagag
    53341 ttcttgcaag tggaatgacc gcaaacataa ctacaaataa gcttatacca ccatacgtta
    53401 atataaaact tactataaat atagcaacta aaactctata aggatgatta gagccaaatt
    53461 tatttaaaat aaaatcagct attgatacag tagctccact ttcttccata aatttagcaa
    53521 gtattgagcc taataagaat attgcaaaat aactcattat atagtttcca agtgcaccca
    53581 tataattgtt tttgtcagca cctagcattg atgttacaac atccatttta tttaaaataa
    53641 caactattaa agttgctatt ggagcagcta tagttatatg aatttcttta actgaaaaat
    53701 atataatagc tatgatacca ataattatac caattggtgc gataatactc ataaatatcc
    53761 ctccttagta gaaggacctg aagaatactt tcttcaagcc ctaaatataa taactattgt
    53821 gcagtatatc ctccatctag taagcaagct tgtcctgtaa tacccttagc attatcactt
    53881 gctaagaaca tagcatagtc ggcaatttct tgaacatcta ataggcgttt ttgtggtaca
    53941 agtgggtata aaacttcctc taagacattt tccaatggta tattacgagt ttttgaaagg
    54001 tcattgaact gacctctgac aagtggagta tctacatatc cagggcataa agcattaact
    54061 gttataccag aatcggcagc ttcaagagca gcaacttttg ttagtccaat aagtccatgt
    54121 tttgctgagt tataagcagc ctttccagca aatcctatta caccattgat tgaggccata
    54181 tttattatac gaccaaagcc ttgttttttc attataggaa atgctttttt agtagctata
    54241 aaaggtgctg tcagcattat ttttatcata aattcaaatt tatcagttgg gaaatcttct
    54301 atcatagaaa catgttgaag tccagcattg tttattaata tatctaatct gccatacttt
    54361 tcaacagttt tgtctatagc gtggttaatt tcttcttcct tagttacatc acactttaca
    54421 ctcatgcaat cataaccttt tttttgtaac tctgttatgg tattatttaa agcttcttga
    54481 tttatatcag agaacattac tttagcacca ttttttaaga acgattcagc tatttgttta
    54541 cctattccac ttgcagctcc tgttacgaat acaactttat ctttaaccat tttcatttcc
    54601 tccaatttta ttttattttt atattaatat tttaagcaat acaaatttat atgtaatacg
    54661 tctaagagat ttttattttc tagttttaat tattttaaac aacagatatt tttccattta
    54721 atgaatctga caatattaaa ggagcctcag tagcagaaat aacatcatct aatgtgaaag
    54781 ctggatttat ttctttaagt aaaattccat ctgatgttac ttccataact cccatttcag
    54841 taactatcaa atctacagca tttgttgcag taagtggaag agtacaatta tttaatattt
    54901 ttgcagaacc ttttgaagta tgttccattg ctacaataac ttttttagct ccagttacta
    54961 ggtccatagc tccacccata cctggaacca tcttacctgg aatcatatag tttgctatat
    55021 taccatattt gtcaacctga agtgcgccaa gaacagttat atcaacatga cctcctctga
    55081 ttattccaaa agaagtagca ctatcaaaga aacatcctcc aggaagtata gtaactggtt
    55141 gaccacctgc atttacaata gtttcatcac ttgaatttcc atcttcggct gaacctaaac
    55201 ctaaaaagcc attttcagat tgtaagataa cgtttacatt atccggaata taatttgcta
    55261 ctttggttgg tagacctatt ccaaggttta caacggctcc gtcttttaat tctttagata
    55321 ctctatttgc aatatattct tgcatttcta atttatccat tataaattac ctccttcaat
    55381 gatgtaattc acaaaaatac ctggtgtatt aacttcattt gggtcaatat caccaatttc
    55441 aacgatttca tctgcttcaa ctattgtaat tttggcagca gatgccatta aattattaaa
    55501 attgttcata gagcctttat aaactagatt acctgcttta tcgacctttg atgcaaatag
    55561 aagagcaaca tctgcataaa ttggtttttc aagaaggtat tctttgctat cgacaacaat
    55621 tttttgcttt ccctcctcaa caagagtacc aataccagtc ggtgtgagta tacctcctag
    55681 accataacca gctgcacgta tttgttcagc aagagttccc tgaggaacta actcaacatc
    55741 tgtttcattg ttattcattt gtcttccagt ttctttattt aatcctacat gagaagcaat
    55801 tatcttttta aattgcttat ttacaaccat tttgccaact cctttgtcaa taaagccagt
    55861 atcattgcaa attagtgtca aatcttttat atttttacta cataaataat caattaaatt
    55921 ttctggtgaa ccattggcca tgaatccacc aaccattatt gtatctccat cttttacatg
    55981 agatagagct tcatcaatgc taactatttt attcatattt cctcctatcg tgaaaccacc
    56041 attgatattc cttgaccacc accaatacaa agtgttgcaa gtccagtttc aactttacgt
    56101 ttttgcattt cataaattaa ggtaacaagt attctagctc cacttgctcc tattggatgt
    56161 cctaatgcta ttgcaccacc attaacattt aactttgatg aatctatttg aagttcattt
    56221 ttaacagcta atgcttgggc agcaaacgct tcatttgctt ctattaagtc tatatcattg
    56281 atgctaagtc cagctttttt cagtgctttt ctagttgcag ggattggacc agtacccatg
    56341 acttcaggtt caacaccagc tgaagcatag gattttattt tagcaagtgg tctaatacct
    56401 agttcgtctg ctttttgttg gctcattagt attaacatag ccgcaccatc attaatacct
    56461 gaggcatttc cagctgttac agtaccatct tttttgaatg caggtttaag tttagctaaa
    56521 ccttcaaatg tcatacctaa tttaggatat tcatctttat caatagtttc tatttttcct
    56581 cgacgtatta aaacatctac tggaacgatt tcttctttaa agcggttgtt ttttatagca
    56641 ttctcagcct tactttgact ttctaatgcc aatttatctt gcatttctct agtaaattca
    56701 aatttagttg caatattttc tgcagttatt cccatatgat actgattgaa agcatcaata
    56761 aggccatctg ttagcatact atctaccatg gttatgtcac ccattttact accaaagcga
    56821 gcagttggaa cgatataagg agcttggctc atattttcag taccacctgc aattaccaca
    56881 tcattttcac cagatgtgat tgattgggca gctagctgga cacttttaag ccctgaacca
    56941 cataatttat ttactgtgta gcttggaaca gaatttggta tacctgcatt tatagcaatt
    57001 tgtctagcaa cattctgtcc aagccctgtt tgaagaacat ttccaattat tacttcatct
    57061 atttcagata aattaagtcc tacacgtgat atcgcttctt taacagtgat agttccaagt
    57121 tgaacagctg aagtattttt aaatacacct ccaaaacttc ctataggtgt tctgactgct
    57181 gatacgatta ctacatcttt catatctaat agttaccttt cttgaatgat aattaaaaat
    57241 tttctgaata aagaaattag gaaacactat aataaagtac ttttttaata caagcttgtt
    57301 tttaagtatt tcaattactt ttattcctaa tgctttaggt tttcctgttt ctaattatag
    57361 attacggcga aaaaagcgtt ttgtctaagt ctaatttttt atatagtgta taagaaaaat
    57421 ttataggata aaaatttata gtagatttag aaaaatattt tgttaaaata ttaatgaaat
    57481 tatgttgatt ttcctataaa atatcattag aagaaaaaat ataatctaaa ttatactttt
    57541 ggggaagggg gtttaaaatg gatataaaac agttgaaata ttttgttgaa atagtgaaat
    57601 ctggttttaa tttatcaata gcatctaaga cacttcacat atctcaacca gcattaagtc
    57661 aaattataaa aaattttgaa gaaagtgaag atgtatattt atttgaaagg tataaaggca
    57721 ggttaaatgg gttaacacca gcaggagaaa gattttatgt aaatgcagaa catatcataa
    57781 atgaatacaa aaatatgatg gaagatttaa gagaagattc agttcaattt aaaggaaaag
    57841 ttagaatagg aatacctcca cttatacttg gaatagcatt ttcagatgta gttgcacagt
    57901 tagttgcaaa taatccagat atagaatttg atatagtaga gaagggtgca tatgacttaa
    57961 atagaatgct tatcttacag gaattagatt atgcagtatt gttacatcca cataaaattg
    58021 ataaaagtgt agtaactgaa catgtgcttc aagaagatga acttacagca tttttaaata
    58081 taaatcatcc acttgctaag aaggataaga tagattggaa cgatttgaat gagcagttac
    58141 ttgcaatatt taatcctact tttatgatac atcataagct aatgcaaaaa tttactgatg
    58201 aaaatgttaa gttaaaaaga tatataatgt ctggttcatg ggattttttg ttgctatcaa
    58261 ccacaaattc tgattttata acaattctac catcaccagt tcatgatttt tttgaaaata
    58321 gcaaaattat agaaaagcct tttaatcatc ctattacatg gaaagttata ttatgtagac
    58381 ctaaaaaaga acgttatagc catgtagacc aacatgtatt taaatttatt atagatttct
    58441 ttagtaaaaa gaactcttaa aaatgttatt aaaataacaa ataaataaat caatttttat
    58501 tataataaac tattagtttt tcatctatat gtttgagagc aataataggt tttacataac
    58561 atggtagagt agtatttaaa gttataatat acaaaatatg tattttttta aacgaaaaat
    58621 aaaaacagtg tatatcttta gataatcact gtttttattt tctatataaa atttgttaag
    58681 tattactaga aaattttttg cttattatag tcaaactcat gactgttaaa aatataagta
    58741 atcctggaaa tacagctaaa tataacttgt caaaaatatg tctttgagca tcttgaagca
    58801 tattacccca tgatgcaaga ggcaattgga ttccaagacc taaaaaacta agagcagatt
    58861 cagttaagat agcattagca atatttaacg aaccagcaac tacaatagtc tcttttaagt
    58921 ttaaaactat atgtcttaat agtatatttc tagtcttgat accagtagct ttagcagcta
    58981 gacagtattc attttccttt atttttaatg tttcgccacg tacaattctt gaaacttcca
    59041 tccaacttaa gaatccaata attagtataa tagtggaaac tttaggtgtt agataagtat
    59101 ttaatacaat caaaactaag aaacttggta tactcataag catatctact aatctcatca
    59161 agaattggtc tagcttacct ccaatatatc cactaataac acctacagca gtaccaaata
    59221 ctacagaaat aagcattgat aaaataccaa cactaagtga aatccttcca ccataaagag
    59281 ctctagagaa gtaatctcta ccaagttcgt ctgtaccaaa gatatgcttt aagctaggtt
    59341 cttgaagttt agaagtagta tcaattgcat tagagtctat atttaatata aaagaagcta
    59401 taattaatat gattattatg ctaagagtaa tacatgcaaa agcaaaggat ttatcttttt
    59461 ttaatttttt taagatactt gtaaacacaa ctagaatcct cctttgctag attttatttt
    59521 agggtcaatt aataagtata gtatatcagc aactaaatta cctaaaatta aaaatagtgc
    59581 tgataacata gttattgcca taattacagt ataatctctt gaaaaaattg aatcaatcat
    59641 taatcttccc atacctggcc aagagaaaac tacttctgta acaaatgcac cagtgactaa
    59701 tttttgtata ctcatgccta ggattgtaac caatgatgtc agtgaatttt tcaagacatg
    59761 tttaaatagt atgacttttt ctgataatcc ttttgctctt gctgtaataa catattgttt
    59821 ttttaattgt tcatttacac tagcttctac ataatttgta aaaatagcag tattatatag
    59881 acctaaagtt attacaggca aaactaaatg ttttactaag tctccaatac tatcatttcc
    59941 aatagtatgc atacctcctg atgggaaaat gttaagttta actgaaaaaa ttgaaatgag
    60001 tatcatacct atccaaaaag aaggtataga aacacctata taattaaaaa cagatgatac
    60061 tttactagtt attgaatttt tatttacagc taaaaatatt ccaagaggta tagctaccaa
    60121 tattgaaaat atcaaagaag tacccataag aataaatgta tttcccattt tttccataat
    60181 ttgttctgta acgggcatat ggtttatata agaaatacct aagtttccac ttaaagtgtt
    60241 tttcaaccag tttaaatatc ttatatatac tggtttatca agccccatat taacccttat
    60301 attttcaata tcctgtgaag acattaaagg atttatatat gcatctgctg ggtcaccagg
    60361 agctaattct aaaagtccaa atgataatat agatattaag attaacatag gtattaaaac
    60421 ttttactcta ttcaatatta attttaacat aagtaaattc tcctaattaa aagagatgtc
    60481 tcgttttaaa ataataaaac aatattattt ttagacatct ccttttctaa ttaataatat
    60541 aaaattttac atcaattatt ctacatacag tttagaccaa tcttcaaata atattgcagg
    60601 agatggttta gcatctttta ttccttttag atttttttga gctgccatta aattttgttc
    60661 ataatctata gtgtaaatag gcgcatcctt agatatatcc tgttgtattt gcttatatat
    60721 ttcttcacgt ttttccttgt ttaactcagt aaatcctttt tcccataaag catctatttc
    60781 agcattagaa tatttagttt ggttgcaata ttgaccagtt tcaaacatac ctctatatgg
    60841 gtttggttct aatccccaag cataaccatt tacatacata tcacattcag tgctattact
    60901 aaatagtata ttgaagaatg ccttactttc ataaggaact atttcagctt ctataccaat
    60961 ttttttcaac tcttgttgag ctactaaggc atagttttta tgcccaaatc tacctgtgtt
    61021 ataacctatt tttaatttat caattttaac accactttta tccaataagt ctttagcctt
    61081 atttgtatct tggtcatatc cttcaacacc ttcttctgta tagaagtctg cttctggaac
    61141 taatatagat ttagcaggta cagaaccttc ttttccatat gctgattcta tcatttcatt
    61201 tctatttaag gcatatgata aggcttgtct tacttctttg ttagccatgt ttgatatatt
    61261 ttggttaaat acaatgtagt ttaatctttc ttcactataa gtataagttt gtaagtttga
    61321 gtttgatttt gccttttcat atccttcagc agatgtcttc ataagtgaaa tttcgccatt
    61381 atttaaagct gcttcttgag atgcttcatt aggaattatt tttagcgcta tagaatctgc
    61441 cttaggttct ccaccaaaat aatctgcatt cttttcaaat actatgcttt cacctttttt
    61501 ccattcctta aacttgaatg caccagaacc aactggatta ttattttttt ctgacttagc
    61561 tatatttgat tctccttcaa acacatgttt tggtattgga gaaattttag atataccata
    61621 taagaaagat tcacttgcag ttggtaaagt aatcttaact gttaaatcat caattttttc
    61681 tactttaact ggtttctcac ccaccaataa gtattgtctt gatggtgaat tttgtttttc
    61741 gtctaaaact gtattaaatg taaataagac atcttcagca gttattggct ttccatcatg
    61801 ccattttaaa ttggatttta attttatagt taattcctta ctatctttaa aatctacttt
    61861 ttctgctaaa taatttacta aatttccttt ttcataagta taaagaggag cataaactat
    61921 atttgatgca agagagtctt ctttaacgtt tgcaaaagct ccattgatta tatctgggtc
    61981 acttgccata ggtattacaa cagttccacc agatttgctt ccactagact tgtctttatc
    62041 attggaagca caggctgtaa atgtaagcat taatgatgaa actaagatta atgatgccaa
    62101 ttttttaaat ttcatattct tataaaacct ccataaaata atatttaaca catatttttt
    62161 attgtataat agtaatcatt attaaatcaa tatatataga aattaactat tatattatta
    62221 taattaatag aaaaaaataa taaaatgtaa gaaaatgttg taatttaaat ttttataaaa
    62281 tacaatcaaa aggtgtatgt tatcttaagt aattttgctg agaggagaaa ataatgagta
    62341 aagcactaat tgaggttaaa gatttaaaag tttattttca tacagataaa gggattgtaa
    62401 agagtgtaaa tgaagtaagt tttaatataa atgaaggtga aactattgga atagttggag
    62461 aatcaggatg tggtaagtct gtaacagcca tgtctttgat gaagttactt ccaacatcaa
    62521 aaatagaagg tggagaaata atctttcgag gcaaagacat tttaaagatg aatgaagatg
    62581 aacttatggg aataagaggg aatgagatat caatgatttt tcaagaacca atgacatctt
    62641 taaacccagc gtttactgtt ggaagtcaaa tcattgaagg tattatgata catcaagatt
    62701 tatcaaagga agaagctaag aaaaaggtaa tcgatatgat aaaactggta gaaataccaa
    62761 gagctgaaga aatatataat tcatatccac atgaattatc aggtggtatg agacaacgaa
    62821 taatgatagc tatggcttta tcatgtaatc caaaattact tatagctgat gaaccaacaa
    62881 cagctttaga tgttactatt caagctcaga ttttagatat aatgaaaaat ataaaagaaa
    62941 aattaaacac atctataatg atgattacac atgatttggg agtagttgca gaaatgtgtg
    63001 acaaagtatt agtgatgtat gctggcaaaa ttatagaagt ggcagaggtt gttgaattat
    63061 ttaaaaatcc aaaacatcct tatactattg gacttctaaa atcaaagcct gctcttggaa
    63121 aaaacaaaga taaaagattg tattcgattc caggacaagt accaaatcca attggaatgc
    63181 cagattcatg ttattttagt gatagatgtg aaaaagtatg tgataaatgt agaactcaga
    63241 tacctccttt aatagaattg aatagtggtc atagtattgc atgttggtta tataaaaagg
    63301 aggagatata attgaaaaaa gaagagagtt tattaaaagt agaaggtctt aaaaagtact
    63361 ttgaagttaa atctggatta tttgataaga aaattaaatc tgtaaaggca gtagatggaa
    63421 tttcttttga tttaaaaaaa ggagaaactt tggctatagt tggagaatcg ggatgtggaa
    63481 aatcaactgc aggaagaacc attcttagat taattgaaaa aactgaaggt aaagttgaat
    63541 ttaatggtgt agatatatat aagttagaga aggaagaact tagaaagtta agacccaaaa
    63601 tgcaaatgat atttcaagac ccatatagtt cattaaatcc aagattaaat gtggaacaaa
    63661 taatatccga ggcagttata gaacataatt tagtgccaaa gaatgaaata aaagataata
    63721 tattaaatgt tgtagaaagt tgtggtcttt ctaagtacca tttaaataga aaaccaggtg
    63781 agttttctgg aggtcaaaga cagagaatag gtatagcaag agcattagca ttaaatccag
    63841 aatttatagt ttgtgatgaa cctgtttctg cactagatgt ttctattcaa tctcaaatta
    63901 taaatttact tatggattta caggataaat ataaactttc atatttattt atatctcatg
    63961 atttgagtgt agtaaatcat attgcacata gagtttgtgt tatgtatcta ggttctataa
    64021 tagaaattgc aactaaagga gaactttact tacattctca acatccatat acaaaagcac
    64081 ttatgagcgc agtaccaata caagacccta caattaagaa aaatagaatt atattaaaag
    64141 gagacatacc atctccaaca aatccaccaa gtggatgtaa gtttcataca agatgccctt
    64201 attgtaagga aatatgcaaa aaagagattc cagttttaaa agaaatatca agaaatcatt
    64261 ttgttgcatg tcatctagta tagatatttc aaaaattaaa tttgatgtat ataataagaa
    64321 taatagaata aactgaaaat ttttttgatt aagatgggat ttcatgctgt taatattaag
    64381 ttagttgata tataagttta atctataata ttattattga aaagagaggt agttatgtca
    64441 attttagtaa cattgttggg attattggtt tgtacaacga tttcaactgt atttagcaaa
    64501 aagtggagta atattcctct tgcaatatat caaattgtac tagggattat attgtctatt
    64561 ttgccattta aattctcatt ttcatttaat ccagaaatat ttgtaatatg tatcatagct
    64621 ccattactat tcagtgaagg acaaaatgta tcgagaaaag agctattaga gcttagaaaa
    64681 ccaattttgc ttcttgcatt tggtttagtt ttaataaccg tgtttgcagg tggaatcttt
    64741 atacattttc ttattcctgg gatgccatta tctgtttcat ttgctttggc agcagtaata
    64801 tctccaactg atttagtagc agtaaaatca attacacaag gattaaattt tcctaaaaat
    64861 ataatgagta tacttgaagg tgaatcttta ttaaatgatg ctgctggagt agtagcattt
    64921 aaggttgcag tacttgctac agttacagga gttttttcaa tagaagaggc agggattcaa
    64981 tttatgatta cagcttttgg aggaataata gtaggaagta ttttaggata cataattata
    65041 aaaataagac ttagtttaca caagtggaat ttggaagaaa ttccaatggt aatagttata
    65101 caaataatga ctccactttt tgtatatttt gtagcagaag aaataggagt atctggaatc
    65161 ctagctgttg taatggcagg gatagctcat ggaattgaaa aagagcattt acaaaataca
    65221 actactaaat taaggataat atcagacaat acttggtatg ttttggagta tgtattgaat
    65281 ggatttgtct ttacactgct tggttttttg ttaccaagta tatatacagg acttagtagt
    65341 aaaaatgaaa atatggcatt ggaattgact tttatttcta ctttaattgt acttatttta
    65401 tttgttataa gatttatatg ggtatattta tggcataatt cttttataaa acctaaaaag
    65461 aatcctttaa ataatttttt tgtaggtttt ttaggtttta aggatgaaga agttataaaa
    65521 gagagtattt ctaaatgtaa atactcacta atagttgcta cttgtggtgt tcatggtaca
    65581 tttacactag caactgcctt atctatacct ttttatttgg ctgataaaga tgtatttcca
    65641 atgagagata ctgttttatt tatatcatca gaagttattc ttataagttt agtattggca
    65701 acaattttac tgccaagatt attaaaaaat aacgtacaag agtcagaacc tttattatct
    65761 gataaagagg catataaact aattttgaaa gaagccattt taaaacttag taatgaaaaa
    65821 gcacaagaag tacaaccagt tatacatgat ttaaatgaac agttggtaga ctcagaaaaa
    65881 ggaatactaa atactccaga taataaactt ataagtatga tgattgcaga agcagaccaa
    65941 cagggattat tagctgtttt gaaactatta gaagatggta aaatttctga tagagccttt
    66001 aaattgtata gattttatat tacaaaatca agaaaatctg ttcaaaaatc tatatttaaa
    66061 attgtaaaat taaaaataag catgtggatt ataaatagaa aagtaaagaa agaagtaaaa
    66121 gaaaaaatta caaaaatagt atctgagaat aaagaaataa tcaaagagtt tcaccatgca
    66181 tatgcacttt ctactaaaac tgctatatca tttataaata aaaatactga tgaagataac
    66241 agacatgagg ccttaatagc aatcagattc tataatcgtt atttgaattg gattactaga
    66301 aagattcaaa atgatgataa gtttgaggca agagtagaat actacagagt aatggcgata
    66361 caaagtcaaa gagacagtgt tcaacaatta gttgaaacta agcaaatatc aagagaagtg
    66421 gctaaagagt tattggaaaa tattctctat gatgaaatga tgatgataga atcataaata
    66481 taatggaata aaatttgatt tttgatgtta aaattaatac taaaaaatag gaaatagttt
    66541 tcaataattt acttgacata tatatttatt tataatagaa taaaaccata aattgaatac
    66601 aatatataag cattaacaag ctggattgtt actggtaagc aggcaatacc taggttaagg
    66661 tatacaggtg aattgtatct taatttaggt atttttttat gaataaggga aattgtattt
    66721 tgggagagat attgattatg attattcaac aaatttataa taataatgtt gtattagttt
    66781 tagatgaaaa tataaaaaaa gaattaatat taacaggatg tggaattggg tttcaaaaaa
    66841 agaaaggtca agaaatagat aaaagtaaaa ttgaaagaac ttttgtaata caagatgaaa
    66901 gctttttaga taaaattagt aaactagcaa gccaggttga tgagaaattt tttgaggtta
    66961 gtactgaaat aattgcttat gcagaggaga acttgaatac taagctttat gaatatattt
    67021 atgtagcact tactgaccat attgcatttg caattaaaag atatcatgaa aacataacta
    67081 taaagaatga tttactacat gagataaaaa gaatacataa aaaagaatat gagattggga
    67141 aatgggctgt agattatata aataaagaat ttgatgtgaa atttccagta gatgaagctg
    67201 gttttatagc aatgcatata gtaaattcaa actataaggg aagttcaaag gaatcactat
    67261 taattactaa aattgtaaaa gacatactaa atattataag atattattat agagttgaat
    67321 ttaaagaaga tgatataaat tatgataggc ttctgactca tttaaaattc tttgcaaaac
    67381 gattagtaaa aaaagaaaaa atcaatgata caaataatga aattatagat ataattaaag
    67441 taaagtatga aaaggattat gattgtgcat ataaaataaa aactcatgta gaaaagaatt
    67501 atgattacta tgtaagtcaa gatgaactac tttatttaac attacatatc aaaagagtta
    67561 tatctgtact gaatttataa taaagagtag tttaatacag aatgtataga tttaatatat
    67621 tatgtttaat tttaatatat tatttaaaat ttaatataaa ataataattt taaaacatta
    67681 agattgttac tgataatgca ggcaagactt atgtttataa aaaaattata atagtttatt
    67741 tttaattctg aaattaggtt aatataggtt tatttatatt aacataagtt taattttaga
    67801 attaagtata ctaatgtaac tttttataaa cttaagtctt ttttatttaa aaaaatataa
    67861 aataataagg agagaaaagt aaatgaaaaa agtatttggt gttttacaaa aagtaggaaa
    67921 atctctaatg ctaccagttg cattacttcc tgcagcaggt atattacttg gcgtgagtaa
    67981 tgctttagca ggagacgcat tgttggctca ttttccagct ttggcgaatc ctacatttca
    68041 acttataata agtataatgg aaagttcagg tcaaattata tttaataact taccacttat
    68101 atttgcagtt ggggtagctg ttggtttaac tgaaggagaa ggtgttgcag cattggcagc
    68161 catagtaggt tttttaattc tcaatacatc tatgggtgtt atggcaggtg ttacagaaga
    68221 tatggtagac aattctatgt atgcaaatat tgttggaata ccaacaattc aaacaggggt
    68281 atttggtggc attattatag ggatagtggc tgcttatctt tataaaaagt tttataaaat
    68341 tgaattacct cagtatctag gtttttttgc aggtaaaaga tttgtaccaa tcgttacttc
    68401 attagttgct atagcaatag gaattatatt gtcttttatt tggcctccaa tacaagaggg
    68461 attacttagt ttctcaaaaa atgttataga agcaaatcaa acactagcag catttatgga
    68521 aggttctttg gaaagactat taataccatt tggtttgcat catgttttcc ataatccatt
    68581 ttggtatcaa tttggagaat atgtaaataa agctggtgag cttgtaatgg gtgaccaaaa
    68641 gatattcttt gctcaactta aagatggagt aaatttcaca gcaggtactt ttatgacagg
    68701 tgcatttcca tttatgatgt ttggtcttcc agcagcagct cttgctatgg tgcatgaagc
    68761 aaagccagaa aagaaaaaat ttgtagcagg tataatggca tcagcagcat taacctcttt
    68821 tttaacagga ataaccgagc caatagagtt tgcgttttta tttgttgcac cagtattatt
    68881 tgcaatacat tgtttatttt caggtttatc atacgcaatt atgcaattat taggagttaa
    68941 aattggattc acattttcag gaggattaat agatttctta ttatttggtg ttcttcctaa
    69001 tagaactcca tggtacttgg ctatcttggt aggtattggt tttgcagtat tatactatag
    69061 tgtatttaga tttatgataa gaaaatttaa tttaaagaca ccaggaagag aagatgagtc
    69121 agaaactaac gctgaagtca ttgaaatgtc taagaatgaa ttagcatcag agattttgat
    69181 tgctttagga aataaagaca atttaaagag cctagatgcg tgtataacaa gacttagatt
    69241 ggttgtaaat gatataaata aagtagataa agaaaaattg aaatcacttg gagcagcagg
    69301 tgttatggtt attggcaaca atgttcaagc tatatttgga ccaaaatcgg attcaataaa
    69361 gtctgatata aaagatataa tagagggaaa aacaaaggtt gaaagtactg ttactaaaaa
    69421 tgttgataaa aataaagtga aaaaaaatat ggaagttgca aatatggaaa atgctttagt
    69481 agaaaagatt gattcattaa caaatggaga gatattagat atagaagaag tgccagattc
    69541 tgtattttca agtaaactga tgggggatgg atttgcaatt aaatctagtg atggattgat
    69601 ttattcacca gttgatggaa ctattggagt tatatttcca actaagcatg caataataat
    69661 aaaatcccaa aaaagtggag tagaaatact tatacattta gggatagaaa ctgtaaattt
    69721 agaaggaaat ggatttgaag tatttgtgaa tgtaggggat gaagtaaaag cgggagaaaa
    69781 attagttaaa atggacttag aatatattga aaaaaatggt ctatcaacaa taagtcctgt
    69841 agtatttacg aatttagaac aaaatcagaa attaagcatt aaaaaaggag taagcacagc
    69901 aaaagaggag aatagagtaa gtatattaag agatgatatt gaaaaaatag gatagctata
    69961 tgatagtgta actaaaagtt atgtgggatt taataaatat ataaataggt tcagttaaca
    70021 tgcaatttat ttaatatata ttttaagtaa tagaaatata tatcattata ttttgatata
    70081 ttttaaaaca ttaaaaaact tgaggtatta gtaagataaa tacactaata cttcaagttt
    70141 tattaaaata aaatttacat aaattatcta ttcatctaaa agagtaatat ccaaaggatt
    70201 tttattgttt atataatttt taggagatac cccgtagttt tttttaaatg cccttacaaa
    70261 actagaataa tcgttgaatc cacatttatt acaaacttca ctcataaggt gaccattggt
    70321 tattagtgac tttgccaaaa ttaatctttt ttgaactata taattgtgta tagacgttcc
    70381 agtatgagat ttaaattttc tcataagata atacttactt ataaaaaatt cagacgatat
    70441 gctatctatt gaaagcttat catctatatt tgaatttata tagtttaata ctttcttaat
    70501 agtttcatca taaaaaacat cttctgttga ttccatattt tcatttttta ggaaaattct
    70561 gtttaagaat atcataagtt gtataaataa tgcatttctc aatatttcat ttccaaattc
    70621 agtattggat tcggaaatat ttatttgctc aataaaactc ttaatagatt caatatcatg
    70681 catatttaaa cgcaatctat tgcatttatt ctctgtagct attttaaaac atttttctaa
    70741 gtcactacta gcatcactat tttttttcat aaattctggg ctaatccata ttgcaattct
    70801 ctcataaaag acatttgaat ctataactgg tttatggatt tcattattgc tgataaagag
    70861 tatatcccaa ggctttagtt tatagggaat accatcaaca aaataagtta catttccatt
    70921 tataaatata attatcttat taaaatcatg attatggtat tcaaattgta tatctttttt
    70981 atctctaata ttaaatattt taaagttatc gtttaagtac ccgattttat tatccatagt
    71041 ttttatagaa gacctttcct cagttatatt atagaaaatt atagagcatt ttttgcaatg
    71101 tttcaagcat ttttaaccat tcacatagta aaaaattctt aatataatat tatatgtagt
    71161 gtaattttag cagaaagagt ttaaagggag gaaagcattt atgaaattaa atgatattat
    71221 acaggggttg gatataatca atgtcaaggg tgaattaaat atagatatta ataatgtaca
    71281 atatgattca agaaaggtta caaaaggtac attatttata tgtataaaag gatttgtgtc
    71341 agatggtcat aagtatataa aagatgccat agaaaaggga gcaagtgcat ttcttgttga
    71401 agaagatgta gcaataaaag gatgtacatt tataaaggta aaagatacaa gaaaagatat
    71461 ggcaaaagta gctgataatt tttacaatca tccatctcaa aaatttaacg ttataggagt
    71521 tacaggtact aatggaaaaa ctagtataac tactatacta aatgagatat taactttaaa
    71581 taagaataaa gttggactta taggaactat aaaaattttt gatggagaaa aagacattgt
    71641 ttccaattca acaactccag aaagtataga tttacaatat cattttaata atatgttgga
    71701 taatggatgt gactactgtg cgatggaagt ttcatcacat tcattggcat taaatagagt
    71761 tgatgaaaca gactttaaac taggcatatt tacaaattta acaccagacc atttagattt
    71821 tcataaagat ttagaggctt atagaaaagc aaaagaaaaa ttatttttta agactactat
    71881 ggcaaatata ataaacatag atgatgaagg tggaaaaaag atatatgaaa atataaaagg
    71941 tataaatgta ccttgttaca cttatggtgt tgatactaag gctgatttta tggctagaga
    72001 tataaaatca gattcggatg gagtatctta tagattaata acaccttcat atgaagaagt
    72061 aatatttata ccagttccag gaatgtttac agtatataat actttagcag ttatagctgc
    72121 ttgctatgta cttggcatac ctaaaccaat atataaagaa ggccttagac tttctaatgg
    72181 agtatcagga aggtttgaaa cagttccaaa tgataaaggt ataagcgtaa ttgtagacta
    72241 tgctcatact cctgacgcac ttgaaaatgt actaaagaca actcaacaat ttgcagaagg
    72301 aaaaataatt tctgtgtttg ggtgtggtgg agatagagat actgaaaaga gacctttgat
    72361 gggagcaatt ggacaaaaat attctgattt atgtattata acttctgata atccaagaac
    72421 tgaagaacca gaggcaataa taaaagatat acttgaagga attgacaaga aaaaagaaaa
    72481 ttaccatgtt gttgttgata gagaacaagc tatagcagaa gctataagta tggcaaaaaa
    72541 ggatgatgtt gtaattataa caggtaaggg acatgaaact tatcaaatta taggtaaagt
    72601 taagcatcat tttgatgata aagaagttgc aaatgagtgt ttaagtaaga tgtagcataa
    72661 aaattaaaca aaatacaaga acaaaaatgt aatatcaagc ttcactttga tattacattt
    72721 ttttatatgt aaataattgt aaaatagata atgcaataat gtaaacacta atatctatat
    72781 taattaattt attgttgtaa taaagtttat aattttgtat aattacagta aatatggaaa
    72841 aataagtatt attataaaat gtttacaata attgtcataa gataatgatt atacatacat
    72901 agattcgaga aaggcaggaa gcataatgtt aagtgatgca aaaaataata ggtatggttt
    72961 gtccataatt gctgtcataa gtatcttagt aattacaatt tcctgtttga tttatggttc
    73021 aaggttgaat aagacattag gtgaagaaac gaatcaatat ctttcagaaa tagcaaatca
    73081 aagcgtcaat gtgttaaaaa aacaaattaa tggagatata aagttactag agtcaatttc
    73141 aatatttatt gaaggagaag agtcttttga agtagataat atcctttcta tactaaaaag
    73201 gcaagctatt aatagttcat ttaaaagaat gggagttatt ttaccaaatg gtacagcata
    73261 cactacagat ggttatatag aagacttctc taaaagagat tatttcttaa aatcaatgca
    73321 aggagaagtg gttataacag gaaaattaaa agatgtaata gaagatgata aaaataccaa
    73381 tagtaatatt aatgtatatt ctgtaccaat ttataaagat aatgaggtta aaggagttat
    73441 atttgccaca catagtacga agttgtatga aaaaatactt tctgtaccta catttaatgg
    73501 aaaaggatat tcttatataa ctagaagtaa tggtgatatt gttttaaatc caagcagtaa
    73561 aaacgccaac tctactaaag aaaatttatt ttcttacatt ggcagaagtg attcaatatc
    73621 aaaatctagt atcaacaata tgaagtcaaa tataaaaaac tttaaatcag gttcattaag
    73681 ttatagtatg tttggaaaag gatattattt aagttatgcc ccaataggaa tcaatgattg
    73741 gtatcttttt tctgaagttc ctaaaactgc tatatctgag aaatcatatg ctattataaa
    73801 acttacatta tcagcatgtg tagtcttgat tataatcttt acggcattaa caatttatat
    73861 actatttata cataaaaaga gtaaggaaaa attggaagaa tttgctttta aagataacgt
    73921 tacaggtatt ggcaattcaa ataaatttaa tcttgaaggg ggaaaatttt tatcctctca
    73981 tgagaaaaag aatctagttt taatttattt tgatatagat aagtttaagc tagtaaatga
    74041 taggtttggg tatgaagaag gagatagagt attaaaggaa atagcagaga taattaagaa
    74101 tatatttaaa gagcaatctg tattttcaag aatttcaaat gacaattttg ctataatatt
    74161 tgaaaagaaa aataatagag agtcaattat agaaatatgt gaacttatac gtaaaaaatt
    74221 gtcaatgata aaaacaagtt tgggagtaga actcaattta attccatcca taggtgtata
    74281 ttttgttgaa gagggagaaa caaatatttc tacctgtctt gacaaagcta tgattgcaaa
    74341 aactacagta aaaagaaaat atttaaaagt ttatgagatt tatgctgaaa atttaaaaga
    74401 aactctcata gaagaacgtg atattgaaca agaaatgcat gatgctttaa aaaatgaaca
    74461 atttaaagtt tatttacagc ctaaggttga tttatcaact actaaaattg taggtgctga
    74521 agcacttgta cgttggcaac atcctaaaaa aggtctaata agtccaggtg tatttattcc
    74581 tatttttgag aaaaatggct ttataacaga attggatatg tttgtattta cccaagtttg
    74641 taaaaatttt aaacgttggg aaaatgaaaa tttccccaca tttcctatat caataaactt
    74701 atcaagagta catcttgaga atccaggctt tatttctgag cttgaaagaa taacaaaaga
    74761 atatgaaatt gaaccaaatt taattgagat tgaattgaca gaaagtgcaa tatttgacaa
    74821 tacaaaaata ttatttaaaa taatgcaaac tttgaaatct gttggattta aaatttctat
    74881 ggatgatttt ggttctggtt attcttcttt aaatatgctt aaagatatgc caattgatgt
    74941 attgaaatta gataggcaat tctttataac agtgggaaat gcaaaaaaga gtcaaattgt
    75001 agtttcaagt attgttcaaa tggcaaagca acttgatata aaagttgttt cagaaggtgt
    75061 tgaaactgta gagcaagcag agtttttaag gtttataggt tgtgatatgg ctcaaggatt
    75121 tttatttgct agaccaatgc caatagaaga atatgaaaaa ttaatattag atagatatag
    75181 tttaaataga aaagaaacaa attaaataaa attgtgaatt ataacataaa aatttataaa
    75241 aaagtgaact ttgttaatca atgttcactt ttttatgtaa aaatatacta ttataaaaac
    75301 ataaatcatt gttaggatat tattttagga attattgggc aaagtttatt aattatgtag
    75361 tattttttct atttgaatgt ttttgaggta agagtatatg ggattatagc aaaatacttt
    75421 agatagtaat aatagta
//
LOCUS       DAGQVA010000009        69947 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.009, whole genome shotgun sequence.
ACCESSION   DAGQVA010000009 DAGQVA010000000
VERSION     DAGQVA010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69947
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.009"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(224..1072)
                     /locus_tag="MIV85_000730"
     CDS             complement(224..1072)
                     /locus_tag="MIV85_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBY2960100.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKKLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(1108..1578)
                     /gene="trmL"
                     /locus_tag="MIV85_000731"
     CDS             complement(1108..1578)
                     /gene="trmL"
                     /locus_tag="MIV85_000731"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBY2960101.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(1772..2989)
                     /gene="nth"
                     /locus_tag="MIV85_000732"
     CDS             complement(1772..2989)
                     /gene="nth"
                     /locus_tag="MIV85_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBY2960102.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDIIEKEEINK
                     KGMNKKDIIEKEEINEKEIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKG
                     ETEKKTKKSSSNKATQKTSKETKSKFKIKNESANEKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            complement(3187..5424)
                     /locus_tag="MIV85_000733"
     CDS             complement(3187..5424)
                     /locus_tag="MIV85_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2960103.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTKQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(5530..6444)
                     /gene="queG"
                     /locus_tag="MIV85_000734"
     CDS             complement(5530..6444)
                     /gene="queG"
                     /locus_tag="MIV85_000734"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBY2960104.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKNRQQKGYLTG
                     MEEPIIESRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            7285..7689
                     /locus_tag="MIV85_000735"
     CDS             7285..7689
                     /locus_tag="MIV85_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBY2960105.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(7946..8941)
                     /locus_tag="MIV85_000736"
     CDS             complement(7946..8941)
                     /locus_tag="MIV85_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBY2960106.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(9225..10061)
                     /locus_tag="MIV85_000737"
     CDS             complement(9225..10061)
                     /locus_tag="MIV85_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBY2960107.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            complement(10549..11112)
                     /locus_tag="MIV85_000738"
     CDS             complement(10549..11112)
                     /locus_tag="MIV85_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960108.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(11210..12139)
                     /gene="glsA"
                     /locus_tag="MIV85_000739"
     CDS             complement(11210..12139)
                     /gene="glsA"
                     /locus_tag="MIV85_000739"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBY2960109.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(12688..14355)
                     /locus_tag="MIV85_000740"
     CDS             complement(12688..14355)
                     /locus_tag="MIV85_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBY2960110.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(14429..15184)
                     /locus_tag="MIV85_000741"
     CDS             complement(14429..15184)
                     /locus_tag="MIV85_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBY2960111.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(15194..15730)
                     /gene="lepB"
                     /locus_tag="MIV85_000742"
     CDS             complement(15194..15730)
                     /gene="lepB"
                     /locus_tag="MIV85_000742"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBY2960112.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(15896..16432)
                     /gene="lepB"
                     /locus_tag="MIV85_000743"
     CDS             complement(15896..16432)
                     /gene="lepB"
                     /locus_tag="MIV85_000743"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBY2960113.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(16532..17842)
                     /locus_tag="MIV85_000744"
     CDS             complement(16532..17842)
                     /locus_tag="MIV85_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBY2960114.1"
                     /translation="MTELPNEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(17921..18637)
                     /locus_tag="MIV85_000745"
     CDS             complement(17921..18637)
                     /locus_tag="MIV85_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBY2960115.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            18882..20153
                     /gene="sleC"
                     /locus_tag="MIV85_000746"
     CDS             18882..20153
                     /gene="sleC"
                     /locus_tag="MIV85_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBY2960116.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(20661..21317)
                     /locus_tag="MIV85_000747"
     CDS             complement(20661..21317)
                     /locus_tag="MIV85_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960117.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(22509..22919)
                     /locus_tag="MIV85_000748"
     CDS             complement(22509..22919)
                     /locus_tag="MIV85_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960118.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(23135..24517)
                     /locus_tag="MIV85_000749"
     CDS             complement(23135..24517)
                     /locus_tag="MIV85_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBY2960119.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNGKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(24528..24887)
                     /locus_tag="MIV85_000750"
     CDS             complement(24528..24887)
                     /locus_tag="MIV85_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2960120.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(25092..25871)
                     /locus_tag="MIV85_000751"
     CDS             complement(25092..25871)
                     /locus_tag="MIV85_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBY2960121.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTVISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
     gene            complement(26332..26943)
                     /locus_tag="MIV85_000752"
     CDS             complement(26332..26943)
                     /locus_tag="MIV85_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBY2960122.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(27035..28024)
                     /locus_tag="MIV85_000753"
     CDS             complement(27035..28024)
                     /locus_tag="MIV85_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBY2960123.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYIEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAINNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(28091..28954)
                     /locus_tag="MIV85_000754"
     CDS             complement(28091..28954)
                     /locus_tag="MIV85_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBY2960124.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(29060..29656)
                     /locus_tag="MIV85_000755"
     CDS             complement(29060..29656)
                     /locus_tag="MIV85_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBY2960125.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(29696..30499)
                     /locus_tag="MIV85_000756"
     CDS             complement(29696..30499)
                     /locus_tag="MIV85_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBY2960126.1"
                     /translation="MIKLTDEEFIVLVNYVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(30535..30975)
                     /locus_tag="MIV85_000757"
     CDS             complement(30535..30975)
                     /locus_tag="MIV85_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBY2960127.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(30988..33090)
                     /locus_tag="MIV85_000758"
     CDS             complement(30988..33090)
                     /locus_tag="MIV85_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBY2960128.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(33351..35054)
                     /locus_tag="MIV85_000759"
     CDS             complement(33351..35054)
                     /locus_tag="MIV85_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBY2960129.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(35080..36039)
                     /locus_tag="MIV85_000760"
     CDS             complement(35080..36039)
                     /locus_tag="MIV85_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBY2960130.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(36175..36693)
                     /locus_tag="MIV85_000761"
     CDS             complement(36175..36693)
                     /locus_tag="MIV85_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBY2960131.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFRVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(36736..37221)
                     /locus_tag="MIV85_000762"
     CDS             complement(36736..37221)
                     /locus_tag="MIV85_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBY2960132.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(37218..37835)
                     /locus_tag="MIV85_000763"
     CDS             complement(37218..37835)
                     /locus_tag="MIV85_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBY2960133.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(37900..38262)
                     /locus_tag="MIV85_000764"
     CDS             complement(37900..38262)
                     /locus_tag="MIV85_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBY2960134.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(39006..39503)
                     /locus_tag="MIV85_000765"
     CDS             complement(39006..39503)
                     /locus_tag="MIV85_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBY2960135.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(39678..40589)
                     /locus_tag="MIV85_000766"
     CDS             complement(39678..40589)
                     /locus_tag="MIV85_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBY2960136.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            41514..42365
                     /locus_tag="MIV85_000767"
     CDS             41514..42365
                     /locus_tag="MIV85_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBY2960137.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            42369..42839
                     /locus_tag="MIV85_000768"
     CDS             42369..42839
                     /locus_tag="MIV85_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960138.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            42852..44162
                     /locus_tag="MIV85_000769"
     CDS             42852..44162
                     /locus_tag="MIV85_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2960139.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            44374..45120
                     /locus_tag="MIV85_000770"
     CDS             44374..45120
                     /locus_tag="MIV85_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2960140.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            45482..47023
                     /locus_tag="MIV85_000771"
     CDS             45482..47023
                     /locus_tag="MIV85_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBY2960141.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKASISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            47058..48164
                     /locus_tag="MIV85_000772"
     CDS             47058..48164
                     /locus_tag="MIV85_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBY2960142.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(48495..49781)
                     /locus_tag="MIV85_000773"
     CDS             complement(48495..49781)
                     /locus_tag="MIV85_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBY2960143.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(49904..53002)
                     /locus_tag="MIV85_000774"
     CDS             complement(49904..53002)
                     /locus_tag="MIV85_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBY2960144.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSSDFEKLLY
                     QK"
     gene            53727..53879
                     /locus_tag="MIV85_000775"
     CDS             53727..53879
                     /locus_tag="MIV85_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960145.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(54172..54876)
                     /locus_tag="MIV85_000776"
     CDS             complement(54172..54876)
                     /locus_tag="MIV85_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960146.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(54867..56474)
                     /locus_tag="MIV85_000777"
     CDS             complement(54867..56474)
                     /locus_tag="MIV85_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBY2960147.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(56728..57906)
                     /locus_tag="MIV85_000778"
     CDS             complement(56728..57906)
                     /locus_tag="MIV85_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960148.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(58132..58626)
                     /locus_tag="MIV85_000779"
     CDS             complement(58132..58626)
                     /locus_tag="MIV85_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBY2960149.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(58627..59388)
                     /locus_tag="MIV85_000780"
     CDS             complement(58627..59388)
                     /locus_tag="MIV85_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBY2960150.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            60110..62944
                     /locus_tag="MIV85_000781"
     CDS             60110..62944
                     /locus_tag="MIV85_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2960151.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            62987..64231
                     /locus_tag="MIV85_000782"
     CDS             62987..64231
                     /locus_tag="MIV85_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBY2960152.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(64646..66386)
                     /locus_tag="MIV85_000783"
                     /pseudo
     CDS             complement(64646..66386)
                     /locus_tag="MIV85_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439072.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(66370..67044)
                     /locus_tag="MIV85_000784"
     CDS             complement(66370..67044)
                     /locus_tag="MIV85_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960153.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(67081..68070)
                     /locus_tag="MIV85_000785"
     CDS             complement(67081..68070)
                     /locus_tag="MIV85_000785"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBY2960154.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(68118..69362)
                     /locus_tag="MIV85_000786"
     CDS             complement(68118..69362)
                     /locus_tag="MIV85_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2960155.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            complement(69404..>69947)
                     /locus_tag="MIV85_000787"
     CDS             complement(69404..>69947)
                     /locus_tag="MIV85_000787"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960156.1"
                     /translation="IKKETDKKVIKEINNIIEKSGFSDIEGRYVRNHFGDHYNKSSYK
                     LAMICVFGVLLISSINIIFIVRSNIIVRLSEICTFRAIGMSKKNVKRMLIKENMIYGV
                     LSMIVAGIISSFNYYKIVSETNKLNQQVYGINNSIKFEIPIYEILIFGSISVFVCVIA
                     VYFSNKMINKLSIVSGIKEN"
BASE COUNT        23260 a        12077 c         7350 g        27260 t
ORIGIN      
        1 aattttttta tatacaattt acaagtacat tttgaaattt ttttaataaa tcttactata
       61 aaaaagtgtg caatagattc ttatctattt acacacttcc ctacaaacta aatctaatat
      121 atcaacactt aatttcatcc aaaataaatc caatttaaca tctcaataat taatattcta
      181 tcctaattta ataaaaaaat aaataatgtc atccaaaaat atattattta ttttttaagc
      241 atatgatacc agtaacacca ggaccagcat gtgcacctat acacacacca atttggaaaa
      301 atctaatttc tttaggtctt aattcatctt gcataacctt agataattgt tctttttcct
      361 taaaatcatc actatatcct atatatacaa tttggtctga taaatcatca ccacaatttg
      421 attttatcaa ttccatcatc ttagaaatta cattcttctt tcctcttact tgagatattt
      481 gcgaaactaa tccatctctt atttcaagaa tcggttttat atttaatata cttcctattg
      541 ctgccttagt agatgatatt ctacctccct tttgtaaata ttccaatgta tctactgaaa
      601 atataacaaa agccttctct tttaattcat ccaaaacagg caatatttca gcaacagact
      661 ttccttcact tgcaagttct cctgctttta ttacaagtaa accagttccc atacaaagca
      721 agttagagtc atatgtatat attttaccat ctacatcatt ctttgccatt acagcacttt
      781 gatacgtacc tgtagctgtg gcagaccctg ctatataaag tatctctcta tcctcatttg
      841 tatatttctc aaaaatttcc ttaaattggg cataagtagc ttgagaagtt tttggatata
      901 cattttcttc tctaagcttt ttataaaatt catctccaga tatatcaatt ctatccttgt
      961 attctctttc ctccagtata actgttaatg aaactatatc tatatcatat ttatctaaca
     1021 aatcttttgg cacgtccgat aaactgtcac agattatctt tagatttttc attaagtatg
     1081 ctcctttctc atttaggctt gttgaaacta cctcatattt gggtatccta tttgtcttaa
     1141 agcctcgtac actacaatag caactgaatt tgataaattt aatgacctag ctttttcaac
     1201 atccaacata ggcactctaa tacaagtatc catatttgct ttcaacaaag gttctggtaa
     1261 tccctttgtt tctttcccaa atactataaa acaattttct tcatatttca catctgaatg
     1321 tgactgttta gcctttgttg tagaaaaaaa gtatttacta tttggatact tttcttgtaa
     1381 ttcttcaaag ctatcgtaat attgtatatc agctatatcc caatagtcaa gcccacatct
     1441 ttttaggtgt ttatcatcca atgaaaaacc cagtggtttt actaaatgta aagttgaacc
     1501 tgttgctgca caggttctta ttatatttcc tgtattttga ggtatttctg gttctactaa
     1561 tactatattt aatgacattt taatcctccc taagtatcgc ttttatttat caaattttat
     1621 tttataaaca gaataacaat aatattatac tattatataa aataatgtta ataataattt
     1681 ttatttcatg tatataatag ttttttatct aacattttca caagtattat tatatcagaa
     1741 aatccctctt gtacaactta ctttctaaaa gttatttcgt ttcattaagt tctttataat
     1801 aattacaatc ttcttttatt gggcaacttg cacattctgg atttctagct ttacacattc
     1861 ttcttccatg aaaaattaat acatgatgtg agtgtgacca tctttctttt ggtatagctt
     1921 ccataagtgc aaattctgtt ttttgaggat ttggctcgtc cactattcct attctattgc
     1981 taactctaaa tacatgagta tctacagcta ttgctggatg attaaaagcg ttactaagta
     2041 caacccctgc cgtttttctt ccaacaccag gtaattttat aagcttttct aagctatcag
     2101 gtacttcacc atcatataat tcacatagct gttcagatgt atcctttatt ttttgagact
     2161 tgcttttgta aagaccacaa ctctttatct ctttactaat ttcttcaatg ctcaaattag
     2221 caaagtctct agctgtgttg tactttttaa acaactctga agtaacttta ttcactctta
     2281 catcagtaca ttgtgctgat aaaatagttg ctattaaaag ttcaaaggct gtcccataat
     2341 ttaactcaca tttagcatct gggtacagtt tttctaactc gtctaaaatc ttatttacgt
     2401 ctttttcatt tgctgactca tttttaattt taaacttact tttagtttct ttacttgttt
     2461 tttgtgtagc cttattagaa ctactcttct ttgttttttt ctccgtttca ccttttttag
     2521 tacttttttt acttactttg atactttttt tatcttcttc aatatccata aaattctcta
     2581 tatctttctc atcaattatc tcatcttttt taccaatcat tttatctatt tctttttcat
     2641 ttatctcttc cttctcaatt atatctttct tattcattcc ttttttattt atctcttcct
     2701 tctcaattat atctttctta tccatttctt ttttatttat ctctttcttc tcaattatat
     2761 ctttcttatc tattcctttt ttatttatct ctttcttctc aattatatct ttcttatcta
     2821 ttcctttttt atttatctct tccttctcaa ttatatcttt cttatctatt ccttttttat
     2881 ttatctcttc cttctcaatt atatttttct tatccattcc ttttttattt atctcttctt
     2941 ccaaaattac atctttttca tttatctctt ttagatttac atttttcata attatccccc
     3001 ttcaaaatac caatttataa aacgctattt ataaatagtt taatcatatc aacaaaaaaa
     3061 taaacatcaa tatataaaac atacaaaata agaatttaat ttatatatat ttacaaaaaa
     3121 agcaaaaacc tattaaagtt cttgcttttt attatacata aatacccatt aaattctata
     3181 ataaacttat tcttttgaca cagtttgtat cttgctgaaa gatattaatt tttcttttac
     3241 caatttcttt atttcttcaa atttaacatc tgtcaatatc tctatagcct cttctactct
     3301 ttcaacagta tatatcttaa attttccatc tcgcactgca tcattaactt catctgataa
     3361 aacgagattt ctttgatttt ttctaggaat tatgacgcct tgctcaccat ttaacccttt
     3421 agttttacat atagaataaa atccttctat cttttcactt ataccaccaa ctacttgtat
     3481 atcacccttt tgatttatag aacctgtaac agcaatattt tgtttaattg atactccact
     3541 aagagatgat aatagtacat ataattctgc agaagatgca ctatctccat ctattccacc
     3601 ataattttgt tcaaaacaaa catatgcatt tagtgacaat agtaaatcct gtgcaaaatt
     3661 ctcagaaaga tagccaccta atataagtac tcctttgtta tgtatagagc cactcatatt
     3721 tacttctctt tctatattta ctatgccttt acttcctggg ctagtggtcg ctgtaatcct
     3781 tgaagctcta ccaaaagagt attctcctgt acttaagact gacaaaccat ttatcactcc
     3841 tacttttctt ccctctgttt ctattagagt aaatccattt tcaattgatt catccatatg
     3901 tgtttccact ctattgattc tttttctctt ttcacttatt gcttttttaa catcacactg
     3961 ctttgtatac tccgaatttc taaactctgc ataagcactt ccttctatta caacttccat
     4021 tattttatta aacttagttg ataatttttc taaatcacca gataatctag tgctaaattt
     4081 aataacctct tcaactgctg atttagtaaa atgccttaaa ttattcttat cacattggta
     4141 tgctataaat cttgctattc cttcttcatt atcttcattt ttatccattt cactatcaaa
     4201 gtctacaaat actttaaaat atttttcaaa atcttcatca tatctatata aaatatcata
     4261 tatatagtgg cttccaatca gtactaattt aacatccaat ggcatatttt ctggtttaat
     4321 tgctgtttgt gtttccaata ttactttttt agtctgcaaa gtctttttaa gaatttccca
     4381 agacattgta tattttagta attggtctgc ataaagtact aaataaccac cattagccct
     4441 atgaaatgct cctgataata gttttgtgaa atcagtcttt atatttccat ttgcataatc
     4501 atactctgcc tttccaaata gatttgctgg acttgggttt atctctacta caacaggtgc
     4561 tgattcttta ttctttgagc ttccattgtc tacaaatagg ttaattttat atttaataaa
     4621 atgctcttta tcatacttat cttttaactc ctcttcatct aaatagaata aatacatata
     4681 ttctattata tctttcttta tattttccag ataagtttga atcttatcat aattttcata
     4741 tttttcacac aatctcttga tatgaggttc tactacaagt ttagctatct cttcttcaag
     4801 ctctaacact gctttttcag ctatttcttc taagtttcta attttatata cgacctgtat
     4861 cgccatattt tctagttctc ttttagcttt gtaaaactct tcatcagact catcactttc
     4921 atcttcctct tctttcaaag ggataaaaac tattcccatt ttactctgtt ttaatttaaa
     4981 tcctttttct tctccatatt ttttaatttg cttcaaaagc atatcttttt ctatttcata
     5041 ttcatccaga agtttatttt tttctatttc aaaattttca ctttcaaacg catttttaaa
     5101 atcttctaaa agactttcaa ttaatttctc catatctttc ttaagttctc ttccaaaccc
     5161 cttttctaat tcaactataa taggctctct agggttttca aaattatata tataacacca
     5221 atctttatgc gtattttttt tggatgcata ctcatttaaa acctttaagg cataagtact
     5281 tttaccagtt ccaggttcac cagctatata tatgttgtac gctggattat ttattttcaa
     5341 ccctaattcc atagcttcta cagctctttc ttgacccaat atataatcta gtggatttat
     5401 ttcagatgta ttattatatt tcaatattcc cccacctccc catatttaac tttaatgata
     5461 taatatgact tttacacaac aagtgttaaa gtaaatacac attaaagtat atgaaacaga
     5521 ctcttattat tagtcatcat acttatctaa aattatttcc atatttctct ttattatatt
     5581 tctacctctc cagctaaaag ctctatctcc atatctcctt ttaaattctt tatttgaaat
     5641 attttgtatc tcatcataat ccaaataatc tattatattt tctttaaatt ccaaaatatg
     5701 agttgttggt atttcaacat tatgtggaca tacttcttga caaatatcgc atccaaatac
     5761 ctttttgcca ttctttaaaa caactttttc tttctctgac aaatctcctt ttttttgagt
     5821 tatatatgat aaacattttt tggggttcat atcataattt cccaatatag catttcccgg
     5881 acaatatttt acacacttac cacatttaaa acaacttttt tctagtggtt tatcttcttc
     5941 aaatttataa ttatttacta tataccctat aaatacgtaa gaaccatatt catcagttat
     6001 gatattatta tttattccaa aatatcctat tcctgataaa taagctaaat acctgtcaac
     6061 taatggtcca ttatcagcaa ataacttgta tttaaaatct gttactgttt tagaaatata
     6121 atcacaaatt tgttgtaaaa agtcctttac tacaatgtga taatcctttc catgacaata
     6181 ttttgataaa tttgaatttt tattcttttc ttgtctattt atatgatatg gaaatgcaca
     6241 gactattata gagttagcat ccttcattat atgtcttggg ttaattctgc tctcaattat
     6301 tggttcttcc ataccagtta aataaccttt ttgttgtctg ttcttaagta tcttttctaa
     6361 attatcatat ttatctaccc ctgctactcc tacacagttt aatcctatta aattacaaaa
     6421 tgcttttaat tccttattat ccataaaatt attccttttt aatctaattg actttttaaa
     6481 tttatttaat ttttttagtc tttttaacct tttctagcta ctaactcttt taaatactta
     6541 atctttttag ctattcaatt ttcttacctg cttaactctt ttagatactt cgtcttttta
     6601 tctatttaat ttttttacct actaactctt ttaggtactt cgtcttttta cctatttaat
     6661 tttttaccta ctaactcttt tagatacttc atctttttac ctatttagtt ttttacctac
     6721 taactctttt agatacttca tcttttttat ttacttattt aactttttta cctactaact
     6781 cttttagata cttagccttt ttcatttact tatttaactt ttttacctac ttaactcttt
     6841 tagatactta gcctttttaa tctattcaac cttttttacc cacttaacct tcttaccttt
     6901 taatataaac tctaaaactt caaatatcat tagttatatt ttgacattct ttctatagtt
     6961 aagcaaaaag attgattttt tcttataatt aatatcccat ttacattgcc atttattaag
     7021 tctttacttg acttatatgg atttcttttt actctcttta ctaaacttat acttattaat
     7081 attatgaagg tcttataata gtctaatatg aatatgccca tcatatatca aattttaaaa
     7141 tttgtaagca aaatacttat cttatattac tacatctaaa gtggaaaatt ttacaaacaa
     7201 gctctgtaaa aacactttaa ataacaattt gcttttaaat catatacaga ttataataaa
     7261 tactgtataa ggatggtgaa aaatttgatt aaaataacaa ttccaggtag acctattagt
     7321 aaatctaatt ttaagcttca taacataaat ggtcaagcat ggatgccttc aaagggaaaa
     7381 tattctaagt atcttgcata cgaaaacatg attgcaggtt ttataaacca acagtatcaa
     7441 ggggaaactg ttgaagaaaa tctaataaca gtcttgaaat tattcttccc aaataagaga
     7501 atgggggatt tacataatta tccaaaaagt atttgtgatg gtattgaaaa aagtggaata
     7561 ataaaaaatg ataaacaact taagccagta cttttatttg attttataga taaagataac
     7621 cctagggttg aaattgaact ttatccagta tctaaatacg atatatccta taatattttt
     7681 gaaaaataaa gattttatgt gttattcgac attatattga tactccagta tttgaaacta
     7741 tactaataca acaataataa ttgtgttatg tctatactca aacaaatgtt tttaaaaagc
     7801 attaagtaaa tatttaataa gtattaaaca aatattaaat ttatataata gctataacta
     7861 tgtaaattta atatttgtat ataagaccac atctaataaa aagaaatcgg agtaaattta
     7921 atacaccgat ttcaataaat aaaatctatc ctagcttttc aacaacagtc ttaagcattt
     7981 ctcttatagg aagttcatat ggacatctac tctcgcaaag cccacagtca atacactcag
     8041 taggtttaac atccataacc tcatattttt ctttagccca ctcttttaat ccatatctag
     8101 tataataacc ttcacataaa aaactcaatg gtatatttat tcctacagca caaggcatac
     8161 aatattcgca tcttctacag aattttttac ctaaagaatt tcttatttct tcaatttcct
     8221 tattatcttt ttcatctagc acaagatttt caagtacagc gacattttgt ctaacctgtt
     8281 caacactctc catacctggt ataactacat ctatgtaatc tttagatagt atatatttaa
     8341 tagccagtgt tgcattgtct aaagcacctc cagctaaagg tttcattact attatcccaa
     8401 ttcctttttc atgagctttt ttaaacactt catctgcttg tccttcaact atattgtaag
     8461 ggaattgtat agtgtcaaat tttccatctt ctatagcttt ttctatagta tttaaattgt
     8521 gactagttat accaatatgt tttatcttac cttgctcctt tgcctctaaa agggcactat
     8581 aagccatttt atctttaaaa agattatcat actcctcttc tttaacatta tggaattgat
     8641 ataaatctat aaaatcagtt ttaaaattat ttaaacttat ttcaacatct ctcttcattg
     8701 aatcataatc tctggacata cttttagtag ctaagaaaaa tttatctctt tttccttcaa
     8761 tggcaattcc gattgcttcc tcacttattg tataccctct tgcactatca ataaagttta
     8821 ttccttgttt ttctaactca tttataacta agttagtatc atcttgagta atcctttgta
     8881 ttggaatgcc cccaaagcca actctcttta ttttcatgtt agtattgcct aaatttctca
     8941 tatctttccc cacctaactt ttaataattt tttatataat ataaatatgt catctttaat
     9001 tatacaacaa attatgagaa tctttgcaat atatttacat actattcata gtataattat
     9061 attttatatc agtctattca taatataatc atactttata cccagttaat ttgtatacaa
     9121 tttttgttat tcctatccat taatttaaat tatcacattt catgattgta tctccaccct
     9181 aattatgttg agggtgaagt atttcacata tttttaataa aggtttattt actagatagt
     9241 atttctttta tcattttaag ctctttcttg tgaccttcat catcaaaagg agtttctaag
     9301 aaaaatggta aatgttttag actaggatgt tccataaaat caattaatgc ttttaatcct
     9361 atctttcctt cccctatagg agcatgtctg tcttttttat ctccaaatgg catcatacta
     9421 tcatttagat ggacagtttt caatctttct atgcctataa ccttatcaaa ttcttccaaa
     9481 accccatcta aatcattcac tatatcataa ccagctgaaa aaatatgaca tgtatcaaga
     9541 cacacaccta ttttttcttt atgctcaatt ttgtctatta tactttttaa ttgctcaaat
     9601 ttaaaaccta tttcagttcc ctttcccgac atagtttcaa gaagtatagt tatattttca
     9661 tcacccttta tggcattgtt caatcctttt actattctat ctatgccaaa atctacacca
     9721 ccacctacat gacttccagg atgaaaacac atgtattcaa ttcctaatga gtccatcctt
     9781 cttatatcct catctatcac ccttgttgca aattcgtata catcatcctt tgtaccaccc
     9841 agattcatag tatatggtgc atgtgcaagc agtggtgcaa aattattttc ttttctaatt
     9901 tcttgaaatt taattatatc tttttcatca aattctttag catttcctcc tcttggattt
     9961 ctactaaaaa attgaaatgt atttgcacca atatatacag ctgtctcagc cgcattagca
    10021 aatccttttg ctattgaaag atgtgttcct aatttaatca tattaatctc cttttatttg
    10081 tactactact tgtactcaat tttaattttg aactactcca ccttaactac atttagccaa
    10141 catatgaaga tggagattcc tatttgatag tactttttca ctaaaaattc gtaagctcta
    10201 agggatgttc tatcccaact aatctcagtc ctcttttaac atatttctag cattgattta
    10261 atttatatta atttttaatt ttaatattta cactttaatt atacccattt taatcaattt
    10321 caaatattat aatcttacat actttgtata ttatctaagc acttcttaga tagtgtatac
    10381 atcttacact atacatatta tttacaaata caataggtat aaaaaaacaa aaaaatagag
    10441 attaaaaatc attgttttac ccataccaaa aactattttt tgattattaa gtaaattttg
    10501 atgttcaatc tctaatatta tatctttaat taatccataa ttaattctct aactaggaca
    10561 ttcctcctca agagtaggaa ctataaccat agctatatca tacttagaac cttcaacatt
    10621 gtgttgtctt ttatttaaaa tttcatctat ctttgacttc atagtgtcac taagttcaac
    10681 taattcatca tgagtaagag aaatatcatg ataatcaact atattttcat tttctaaaac
    10741 atcttcctct gctgccttat aaaaaacttc actcatattt tcaaattttg atatgtacaa
    10801 ttcttctttt tcttccccat tgtctaaaga aaaattaagt atcctattcc ctataaccac
    10861 attttttgca cttggataat agtacttttc cacaatcccc gactttattt tttcctcaac
    10921 taattctaaa ataccaactt tgtataacat ttttatatgg tagtttattt ttgcatgagg
    10981 ttcttccaat aattgagata attgttttgc tgacaatggc gatttgtcaa atgcttttag
    11041 aatatctatt ctacgtggat gcgcaatagc ctttatgcac tccaaatctc gtaataccaa
    11101 tacctctttc attgacccct cctaaaaaat ttatttaatt catatttctt tacaatttaa
    11161 ttatatatta aattatatgt tgttgtcaaa aaaatccttt cttaatattt taaaaaatat
    11221 ttaatttgag tttatttgac aactcctcta aaactttaac tcctgcgacg ctgttacctt
    11281 ttttgtcaag cgcaggtcca taaacaccaa tccccatgcg tcccggcaca gaagccatta
    11341 taccaccccc aactccagat tttgcaggaa tgccaacttt aatagcaaat tccccagaag
    11401 catcatacat tccacaagtc atcataaatg tcttgacaat cctagaaacc atttcactca
    11461 ttaaatgctc accattttct atatctactc cataatttgc aagatttatt ccaattctcg
    11521 ctaaatctac agaatctatc tcaattgagc attgtttaaa ataaaggtct agaacatctt
    11581 ctacattccc tctgataaat ccatcacttt tcaataagta agccatagct ctgtttctat
    11641 ctccagtcat tttttcagac ttatagacat catagtttat tcctatatta tcattttttg
    11701 ctaactttct aaagaaacta agcattcttt cttctttttc ttctaaacaa ctcccattta
    11761 taagggaagt ggttactata gcccctgcat ttatcattgg attacagggt ttttttgtgt
    11821 cattaatttc aagtttcatt attgaattaa atgggtcccc acttggctcc attccaacgt
    11881 ttgaaaaaac gtcttcccaa tcattatcca taagtgccat agcaagcaca attggttttg
    11941 aaatactttg tatagtaaac tttgtgctac agtttccagc actataaaga ttattttcgc
    12001 tatctatgat acaaattcct aaatcatttc ttctagcgtt ttttaattct gggatgtaac
    12061 tagcgacttg tccataatta gtatacttct tattagaact tataatttct tttaataatg
    12121 tctcatctaa cgtattcata tgcacctctt atattatgtt atatattcta ttttagcaca
    12181 agtttatact ataataaaac aatgttaaaa aaaattatac tttaaaatta ttttctacaa
    12241 gaatcaattc atttttcaaa caatttaaat agtttaaaga gcttaataat ttagtaattc
    12301 aataatttaa caacctagta atttagcaat ccagcaatct aataatccag taatttaaat
    12361 ttttataaca ccaaaaattt ctaacccaac accttttact cttttactct tttactcttt
    12421 tactctttta ctcttttact cttttactct tttactcttt taaaaaataa tcacataaac
    12481 taacaaaata ttaaacaaaa aagtaaaatt taaaataaaa agcttgcttc atacaaaagt
    12541 ataaaacaag cctttttata tatcaactca aactttaaaa tctgtatcaa tttaattctc
    12601 cactttacac ttaatatact taacataaac caataacact acttgctatg ccatttaatc
    12661 ttcataaaac aatctataat acacacatta atcaactatt ttacttcctc caataaattc
    12721 cctaagaatt gaaatacctg gtatgtcaga agtatcgtcc aattcaacaa aatactgcaa
    12781 aaactttagt aatctagtag cttcaatatg tgcaggatta tcttccttta tctcttccaa
    12841 caaaggtttc gcaaatcgtt ttaaaactgc caattcatat acacaagcag agttaaatat
    12901 agcatctgcc tcctcttggt acgggaatat attcttcttt tctcctcttc taactgatgc
    12961 ccattgtaaa atagtattat cagcactata tcctctaaaa ttatagtctc taacaattct
    13021 tcttatcatt ctcaaatcag cagtagggat tcgattatgg tcatccaaat ttatttgagt
    13081 aagggcactt atgtatatct taaatttatc ttcatctggt atagatgatg ttaaaatagg
    13141 atttagccca tgtatacctt ctaatataat tggctgattt gaatctatct ttatcttttt
    13201 accagtgtat tctctcttac cttctttaaa attgaatctt atatcatcaa tttcttcacc
    13261 agctaaaagt ttctttaagt ctaagttaaa cttctctaaa tctattgcat aaattgattc
    13321 aaaatcataa tttccatatt catctaaagg agtatgtttt ctatctataa aataatcatc
    13381 taaagaaatt gaaataggat ttaaattatt tactctaaga tgtattgata atctgtgagc
    13441 aaaacttgtt tttccagatg aagatggagc tgctattaaa actactctct tattgccatc
    13501 ctttatcata tccgctattt gagatagctt cttttcatgc aatgcttcaa atgtccttat
    13561 tatatctcca tattcattgt tttctattat tttattaaga gatactacct tgtcaattcc
    13621 cataagtctt gaccattctt ctgcttcata atatacactt gatagcttag gttgaggtac
    13681 aaatttcata ggaagagtct tatcttcttc actaggtcct aaaattataa cgcctccatt
    13741 ataaagctta atatcaaatg attttatata accagttgat ggcaacatat aaccataaaa
    13801 atggtctata tagtttctac acttatatac tttagcacta tcatactctt tgtatttcaa
    13861 aagctctgcc ttttcataca tttcattatt ttcaaagata gaaatagctt catttcttgt
    13921 aacttcaatt ttttctataa cataatcgtt gtttactatc tctttcatct tgttttttat
    13981 attttcaaca tctgcttctt taagctttct atctatatga acttcacaat atagcccatc
    14041 tgatagtgaa tgttctattg taactctgct atcccaaaag atttctctac atgccattac
    14101 aaatataaat gacatgactc taaagtaaac tctctctcca tcttcattag tagtatctaa
    14161 aaaatttatc tcacaatcct tcttaactct acaatttagc tcttttagtt tattgtctac
    14221 aactgcaagt gttatataac ccttatgctc atcacaaaat tcttttgcta tatctcccaa
    14281 tctgattcca ggggaatttt cttctaatga atattcctta tcttttcctt ctatttttaa
    14341 gtttattttt ttcacttcaa catctccttc cttttgatga atataaattt taattaatga
    14401 ggcatatcaa caagataaag agaggtattt aaccctctcc tacaatatta ttcaatttac
    14461 ttatagtatc ttcaatgtct tcgtaattta tttctaatac taaatattct gcatctaatg
    14521 ttaagacctc tttaatcccc tcttcagata aaattcctct tcctatacca acatgtgtat
    14581 cattgatacc atcattatca cttaagtgta tcagtcttat tttatccttt aagttcttta
    14641 cataagcatc ctcatcaatt aaacagtgtc cagtatcgta acaaaaacaa atcttagaat
    14701 ttttaatcct cttaaatata tattcaaaat cataagatat atttccaata tttgaaaaat
    14761 ccccaccttt tgaataagta ttctctatac atacatatga atttgtattt aatttatcta
    14821 aaaaatccac actatttcct aaatatttgt ctctattctt tctaactcta tttgtcataa
    14881 catatcccaa atgaaggtta aaatacctta aatcaaatcc ttttagttca aattctatct
    14941 tctcaataaa atttatccat gaatttcgta tatactctat gttttcgcaa gtatttaatt
    15001 ccataggcaa gtgtatccct atagataatc ctaacttaga aattctctct ttatatttac
    15061 ataactcact acattcagat atattgtcaa ttccaatctc taaatgagtt atttgcttta
    15121 tactctcaca aatgtttaaa gcctcctcaa tattaaacaa taaggacgct ataccaactg
    15181 ccatacaaat cacctactca aaaataccta tatctgtaaa aggaaatact cttaaaataa
    15241 cttttccttt aatattttct tcatctacta atcccacttc tttatatcta ctgtctaaac
    15301 taacttctct attgtctccc atcgcaaata cttttccctt aggaatcacc atatcaatat
    15361 cgccttcagt ataattatca tgtatatatg aaacttcatt taataactta ccatttatat
    15421 aaaccttaga atccttaatt tttagatggt caccaggaac acctataacc ctttttacaa
    15481 gctctttttt ccttccattc tcttgtaata aatcagtctt aaatatcatt atatctccac
    15541 attttggttc tgataactta tatgtcatcc tgtttgctac caaataatca tgtgatttaa
    15601 gtgttgggta cattgattct ccatttacta atgttggttt tataaaacga gttataataa
    15661 atgcaaaaaa aagtgcagta ataattattt ttatccactc tacaatctct tctttaatag
    15721 tttcattcat tcacaaattc tcctttatag ttatattatc tttattgata atgtctctta
    15781 aacactatct tttagataag tctactaaat aaggtgttgt cttttttata tagacaacta
    15841 ttgtgtatgg tctggtgatt tcagctaatc agcgattgct ccaaatttta tatgtttagt
    15901 caatagttcc tatcttagaa aatggataca atctgactag aacctttcct aaaatggtat
    15961 gctcgtcgac caatccaacc tcatcgtatc tactatctaa acttttttct ctattatctc
    16021 ccattgcaaa taattttcct tctggaacta cgatatcaat atctccatca gtacgattat
    16081 tatgtatata ggaagtctca tctaacaact tatcatttac atataccttg gagtcttgta
    16141 tttttacatg gtcaccagga acacctataa ctctttttac taaatctttt ttctttccat
    16201 tttcctctgt taagtcggtt ttgaatacta ttatatcttt gtattttggc tctcctacct
    16261 tgtacgcaat tctgttaact atcaaataat cacgttcaac taatgtagga tacattgatt
    16321 ctcctttgac tattgttggc actataaaac gagttattgc aaatgccaaa acaagagcta
    16381 tgacaatcac ttttatccat tctacaactt cttttttaac tgcttcaccc actaaaatcg
    16441 tctcctctgt gttaaatatt aagtcaatct acagcaaaat aatctaccat aaacctacaa
    16501 tataaatatt atacttcttt tttctaatag tttaaaatac ttttctaaga cctttaggat
    16561 aatgattctt aattacacca gaagattctt ttccccaacc taaaggtatt ccttcaaccg
    16621 aaaccaaaac ccatcctcta ctatcattag aatttacaac atcccctttt aaatatttaa
    16681 gaattgattc actctgtaca ctgaagtttt caacattttt tacatcttca acttttaagt
    16741 aatgagatag tgcatgagaa ggctcaaatc tattcttctt taaaacccct aaatgcaaac
    16801 catatctcaa tacttttagt tttttcgtat ctggatatat ttcaggaagt aggtacaaat
    16861 tttctcctct taaataaaat ttattttttt tattactata aaaatcaacc tttaaaaatt
    16921 tcttttcaaa ctccctataa tcctttattt ctttatctaa attttttatt tttaattctt
    16981 tgacattaca ttcttcttct tctaattttt ttattttggc aacaaaatga ccttctccct
    17041 ttatcttatg aggccataat ctttccattt caataagttc tgcatgtgga tattcactga
    17101 taaactcatt tataacatgc tcattttcct cccttgaaaa agtacaagtt gagtaaatta
    17161 aaatgccatc cttctttaac attttatatc catctcttat aatctctttt tggatggatt
    17221 gacattctac tacctttgca taactccaat ctgatatggc aacctcatcc ttcctaaaca
    17281 taccttgccc agaacaaggt gcatctataa taaccttatc aaaataccca ttaaacgtct
    17341 ttcttaagct attagaatcg gtgtttgtta taatacaatt tctcgctcca aatcgctcta
    17401 aattttcccc tagagcctta attctactag cattaatttc attagaaacc aataaacctg
    17461 tatcgtttag cttagatagt atatatgtag attttccacc aggagcagca cacatatcga
    17521 gaactttttc accctcttta atatctgcct ttggtattac actcattgca gaaggctctt
    17581 gcaaatagta tgctccagcc tcatgcagtg gatttctacc aggtctgtca attttatcat
    17641 cataataaaa accttcttct gcccatggta tttgattcaa atcaaacaac tccaaatcaa
    17701 ataatttttt cttgtcaatt tttaaagtat ttattctaag cccagtagtc ttactttcct
    17761 cataactttt tataaaatca tcatattcat cttttagtat ttcttcaata tcttctaaaa
    17821 attcatttgg taattctgtc aaatctataa tcccccttca atctgcttta cttgtgtgtc
    17881 atttattata ctttaattat ttatgtcttt cctttaaatt ttatttcttc ttctttttcc
    17941 taagattacc gaaaaacact tttttagagt gattcatata tttctcaagt ttatcaagat
    18001 ttatcttcca caaaattatt acataaacta taagtaatat aatagcccat ctatattcta
    18061 tcatcaatat gaaatcaaaa actccatgta ataaaattgg aattaacact gccataaaca
    18121 aatactcacg tcttttattt ttatttccct caaatttata cttagaaata tagtagccca
    18181 tagtaattgc aaacattaca tgagctggta tagagataac tgccctatta ataccaactt
    18241 gcagtgctag atttctactt tcagaaaaaa tataaaccat attttcaatt gttgcaaatc
    18301 ctaaagctaa aaatacagag taaataatac catctaactt ttcagtaaag tgtttttctt
    18361 taattagggc aggaatcagt atcagagctt ttacaccttc ttctacaagt cctgcaacta
    18421 caaatgatac atatattagt tctgaatacc cttcaaatac attaaacttc atcagtaaat
    18481 tttctaaaag tataattata acacttagaa aagcacctat taaaaaaaat ttaattagat
    18541 ggattagggg ttctctacaa tatctatctt tagaccttat ccaaaacatt cctatcaata
    18601 taggaactat tgctaataaa aataaatcta gcttcataga ttattttcct ttcaaaattt
    18661 ttgatttatt tatgatttat atcatctact tatttttaac ttattcgtgt tttaaataca
    18721 tactaaaata tacattaaat tattttaaat tatttaaata caaatatact caaatactca
    18781 aaaaaattta aatttatatc tatattattt aacaaatttt aagctatatt catatcttga
    18841 aatataaggg aactaaattc atttaaagaa agggtgattt gatgcaagat ggtttcttaa
    18901 cagtaagcat aattgatgct actaacaata gacctattca aaatgcagta gtaaacatat
    18961 attcaatgtc taatggtagc caaagctcat caactttata ccaaaaccta agaagtaatg
    19021 aatctggtca agtgactggt ttagtattac cagcaccaga tgtagattac tctctacaac
    19081 catctgatgt tagaccttat agccagtata tagtggaagc catagcagat ggatatgaga
    19141 cagttgtcat agaaggaaca cagttgttag ctacaattga agcaagacaa ggagttccca
    19201 tgtctcctag aacaagaagt aagcgttctt tctcaagaca aagtgagttg atttttgaca
    19261 taggagaaca tactctatat ggtacttatc ctcctaagat tccagaaagt aacttaaaac
    19321 cattaccacc tcctactggt ttcgttgtat tagataaccc tgtagtgcct gaatttatag
    19381 tagttcatga tggtttgcca gaagattcat cagctccaaa ctattggatt ccatttaaag
    19441 agtacattaa aaacatagca tcatctgaaa tatattcaac ttggcctgaa cagacaattt
    19501 atgcaaatgt aatagctata atatcattta ctttaaatag agtctttact gaatggtata
    19561 gaaataaagg atataacttt acaataactt caacaacagc atacgaccat aagtttataa
    19621 ataatagaaa cttatttgaa ccaattaacg tagttgtaga tgctattttt aatactttta
    19681 taaaaagacc tcctacatca agacagccac tattagcaca atattgtgat ggacaaaaat
    19741 cccaatgtcc tgaccaaatg actcaatggg gcagtaaaga cttaggtgac caaggatatg
    19801 actatgagag tatactaaga tatttctatg gagatgagat agtatttgaa agagcgccta
    19861 tagtaagtgg tgtaccagtg tcattccctg gtactacact acaagttggt tcttctggac
    19921 agtatgttag aaccatacaa aatcagttaa atgctatatc taattcttat ccagctgtac
    19981 caaaagttat agaagatggt atctatggaa cagatacaga aaacgctgtt aagatattcc
    20041 aaggaatctt tggtttacct caaagcggag tagtagattt taaaacatgg tatgaaatat
    20101 ccagagttta tgtagctaca actagaatag cttctttaaa tcctttaatt taaagcttga
    20161 tttagaacat aaactcaaat tattgaataa aattattaat ttaaaataaa aatggctgtt
    20221 atgaactaat atataccata agtattactt ataagtattg tagtcttaac agccattttt
    20281 tagttataac ttgttttttt agaatcttaa aactttaaat gggggatttt aagcttctta
    20341 aaaacagtgc ttagcaactt agatttcttt aaaatattat atttattttt aagtttaata
    20401 aaatgctatt ctaacgaaaa acctactttt tatttaaaat ctcacttatt atttaaaatg
    20461 ctacttctca cttagagtat tactccttat tatttaaaac actatctatc acttagagta
    20521 ttacttctta ttatttaaaa cactatccat cacttagaat attacttctt atataaatta
    20581 ttatttatta taaatacaaa taatattaat ttaaaaagtt attcctaatt taaataatac
    20641 tactatcttc atcagtgaac ctaaactgca actttagact tattagctaa agccaatatt
    20701 agacctaaag ctatagatgc aaatgcagaa gcaattactc tatactcagc agggaataag
    20761 aatacaattg tatgacatgg tatccagaaa aatggtatag tttttaaaac actaaaacca
    20821 aggtaagcat tccagtccac aatatttacc acatctttaa gttttacctt aatccccttt
    20881 ccaacctcat attttttatc tataaaacag tccataacct tatggaataa aaatacagtt
    20941 ggtgacatta gtatattcat agttgcactc ttaaatagag catttgcaaa agctattccc
    21001 tcaaatggaa gcataccatc cacttgtgct tgacctacac ctgatgagta gattgacatt
    21061 ccatatgtgg taactacacc tattattccc caaactattg ctctataaaa tactcctact
    21121 ggtattttcc aatccttata caaaattcta gcaccaagta aatctcccat tgtagctaat
    21181 acagcaaact ttaaaaaacc tccaatatat ggatgtgcac ctgttgcttc cataaatact
    21241 tctctactac ttggtattgc taagacagca ataatacaaa taagaactcc actccatata
    21301 aaatcgcctt ttttcatatt tataaatact atttaatata taaatagttc tcctttctat
    21361 taaagattta tttaatttac aatctatcta caattattta ttaatcactt attattagat
    21421 attcattttc catatttaaa tttattctat ccctttatct atttattttc ttactactct
    21481 atccaccatt atctatatat ttattttacg attactcttt caccctaacc ctttaattat
    21541 ctattttttc tgatattctt atctaccatc atccatatat ttattttacg attactcttt
    21601 caccctaacc ctttaactat ctattttttc ttactattct tatccacatc atccatatat
    21661 ttattttacg attactcttt cactctaacc ctttaactat ctattttttc tgatattctt
    21721 atccaccatc acccatatat ttattttaca attactcttt taccctaacc ctttaactat
    21781 ctattttttt ctggtattct tatctactat tatctgtata tttattttat gattactctt
    21841 ttaacctacc ccctatactt tatagtaata tgtttttaac ctttttcatt attcccaata
    21901 tgctttataa ctacaaatac tctcccccct taaaaataat aataaaatta atcaataaat
    21961 ttataatcat attattactc tatgtattaa gcaattacta tgccaataaa ctttgatttt
    22021 tttaaacaaa tcttaaaaat cctaaaatgc taattttctt taacttttaa tgaatctaat
    22081 agataacatt taattttcgt tatatttttc agaatatttc tattattatt tttaagaaaa
    22141 aaaaataatg ttaacatttc ttaacataca ttaaaaaatg ttaacattat aaattgggtt
    22201 taatactttt actttgactc gatttacttt tattctactt cttactttat ttttaactta
    22261 gactttattt ttttattact tatttgagtc ttatttattt tattatcact ccatatgttc
    22321 aattacattt gtctaaattc tttgatactt ttattacata attttaacaa gcttaagtgt
    22381 tatttgggta gtgcagttga taattattta aataatcatc aactgcatgt ttatatcatt
    22441 acagtagctt aatgtattta atcatactta cttaggattt tgaaatatct tagagattat
    22501 atttaacatt agtcaattgc tgcataattg taagcaattg aaatttgaga cccatcttca
    22561 ttttctatag tgataggctt cataattttt aatccttcag tttttatctt ttctaattct
    22621 tgttccattt tcttaattgt ttcctcaagg tctttttgac ttacatcttt gactgcatta
    22681 gggtctttag catagtcttt taattcttga atatgtttag catactcttc ataagtataa
    22741 tgctcaacac catacttttc caattcagta gggtcagtta ttcctgattt tattagagat
    22801 tcaagtttag gtaaagcaat attagatgaa tcatttccat ttgcaaatac tgctccagtt
    22861 cctcctagta ccattgcaga taccatcatt gcacttataa gggatttttt tattttcata
    22921 accaatcttc ctttcttaga gatttatttg ggtagtgtag tttgaaatga ctattgcaat
    22981 agttatcaac cacatcctta gactatcaca gtagtcatgt ttatgtcaag cctttttaaa
    23041 aaacttttca ataaaaaata ctatctcaaa acaaaattaa ttattttgag atagtatttt
    23101 aattctaaat cttttatatt actaagattt atggttactc tatccatgtt ctatattgtt
    23161 ctttattaac tgctaacaaa ttcccttttc ttgatatgac aaagcgatta tcattatagc
    23221 cactttgctc aattgaaact tctcctgaat cagtataaag tacatcctta ccattactag
    23281 atttatttac atacgtttct tcgctattct cagaattagt tactttgctc atagatgatt
    23341 cttcatgctc tctaaattca attacagata cttttgccgt actaaaatga gtctctccat
    23401 cacttttagc tttactaaca agaatatcag attctacttt gggagaatat aaatcagttg
    23461 atttactact tattgaaaat ccaattttat cactttgttc attttttgtt aaaccaaaag
    23521 attcaacctc attaatctct ttattttctg ttgcaaaaac aagacctgtc ccacaaacta
    23581 atacagttga aactaaaaaa gtaacataag ttgatttttt aaatttcata atattaacta
    23641 ttctcttttc tatttttgtc tttccaaatc cactacatat tgtcattgaa aatggattat
    23701 tctcctctgc tagacttatt agtgtggttg cataatcagc cctatattct tcaccaagta
    23761 tactcataac cttttcatca caactaaatt ctatgtcttt atttagtaaa aaaaacatca
    23821 cccaaactaa gggattaaac caatggacaa caagagctac aagcataaat aactttaaca
    23881 gattatcaaa gctattaata tgaaccattt catgagttaa aacaaagtct aaagtttgat
    23941 tattagcata attcatttgc tttggcaaaa taattcgtgg ttttaaaata ccagatgtaa
    24001 gtggtgtcct agtaaattca gatatgcaaa caataaatct tctaaaacgg ctattcttac
    24061 acatccattt tttaatgaac tcatgatttt ttatatgaat tgaagtttta aaaagattaa
    24121 ttattttaaa atatctaaag cataaaagta tgctaaacat aatagtaact ataaaagaca
    24181 aaatgcccaa catttccaac atcataatat tttcaatatt agacattatt tcaaattcgt
    24241 cagaattgtt tttacctgta gagtcactag ctttcttaag agtataattt tctgttgatg
    24301 tattacccaa ttccacatca aaagtcgatt caattatact ataaatacta aaaccagaat
    24361 ttaaacttac tggtattaga agtttaaata aaacaatcaa ccacaataat acaaatacct
    24421 ttttaggtaa ttttttaaat aaacatgctc ttataaaaat aactattaaa agtaatactc
    24481 cagaagtaaa actcatttct aacaatttaa tgaacataaa tcttacctca ctttaatttt
    24541 tcaacaattt gtttaagttt tgtaatctca tcacttgaaa gattttcttt attaataaaa
    24601 gctgaaagaa atttttctga agaccctcca aacattttat taattaaagt ttctgtttcc
    24661 tgtttttgta cttcctcttt gcttattaaa gctttacaaa caaaattcgg ctcaattctc
    24721 tctattgcac cttttgacac taattttttt ataacggtat acgtagtgtt tctattccat
    24781 cctgtttctt cttttaaaat ttttactaac tctccagcct tgctttctcc tctctcccat
    24841 agaacttcca ttactttaag ttctgaatca aataatttta tctccatata aaatcgctcc
    24901 tcaaatatag ttatcacaat agtcattact ataataaaaa actatcatag tagtctatac
    24961 tatgtcaatc atttattttt taataataaa aactgtcttt ttaaaaaatt cttataaaag
    25021 acagttttat caatgttata ctttaatctt taattaaagc catattttat ttaaatatat
    25081 aactatatat cttagtacat agtataagat ttttctttat ctaatagtat atcctctaca
    25141 tctgggtttt cttttactaa ttgtctataa aaattacaat tagtaacacc tacatatgga
    25201 attagccata gtagacctat tccaagagta gctattgaaa gtatatacca tcctataaaa
    25261 ctaaagttta gtacaaataa tttaagtaca tttcctttca tcatatctaa actagcaccc
    25321 attgatttaa atacacccat attatccttg tcttcacaaa ttaagaaagt agcttgagaa
    25381 acatataata gcaatatata aaccggtaac ataagaacaa gtattataag aactagagtt
    25441 attccagtag aaataacagt ccctattcca acattatcac ttgataaata ttcaattgct
    25501 ccactagtaa gtaaaactcc aaatgataaa aacgctccta taattgtgat tataaaagaa
    25561 taaatataaa caataattga ttcaaataaa taaaaaccaa aacttcttaa ataaattctc
    25621 ccacttacaa agatatctcc tatcttgact ttttcatctt tagtaatttt caagaacata
    25681 catgtaaatc ctgctgaaac gcaaaaagct attacagcca ctacaatagt agtcaatggt
    25741 tcaaaaggta atcctacaat tgatattaat actatcaatg caatatatac tgccatagaa
    25801 attgcacata tcccccagtt tccagataac tgagctttag atactcgttt taattcttgc
    25861 cttgatacca taaaaaacac ccctttcatt ttataaaaaa acttttaaaa atataaataa
    25921 tcttttaacg tataatatta atatatcata ttttcgacta tataagatac aattattcac
    25981 catgttttat caagatatac cataattgta ttactagttt tatatagtca acattaccaa
    26041 atacatcaaa taaatttgat taattattca acaagtaata aaataatttc tattaattat
    26101 actttattta gtaaacaaat tatttaataa aaaaattacc taatacagta aattaattgg
    26161 taagataaat tatttattat tagtaaagta aattatttac tatttatcaa gataaattat
    26221 ttataaaata aatcatttat aaaatataat ttatactttg aaaataaaat aaactatctt
    26281 ccaaacattt tattatatgc ttaaaagata gttttgtgtc tttaaaataa attaaattgt
    26341 atatattcct tcacataact tttgtatatt actaggtggt tgccatttac catctttttt
    26401 agtatatgta atcatagttg taacttcctt agttggtttc ttattgtaaa ggtctataat
    26461 catttttgtc atatcatctt gaacttcttt ttctttttta tcgtaattct tttcatcagt
    26521 tacataagat tttactaaag tgttcgcttc actcattact ttactagtat ctaaagcttt
    26581 acttacaact ttcaaagtta tcttatcctt actagaagat tccactgtta ctgtcttttc
    26641 aacaccttga attaatttaa caattgtttc gtatatcttt tcagcatttt ctttaccata
    26701 aagaggtgtc aattgagcaa tcattgaaac cttgtccttg ctgttataag tttgaatctg
    26761 tttatattca gcttctgtta atgcatcaga aattcctttt tcatcatact tatacatttc
    26821 taatgcagct aaattagctt caaaattcga ctttactttt tcttctgcat tagaacaccc
    26881 tatagttaga actaaaacta gagccataat cgtagataat attaactttt ttaccatttt
    26941 catacaaaca tcctccctca attaaaataa taaaaaattt atttatcaac attataacat
    27001 aaatttgtct aactatagaa ttattttgaa tattttacca cttccagtct attccaatac
    27061 cgttttcttt tgctttatcg tatattcttt ttgctgttac gacatcttgt acacctatcc
    27121 caacagtttt aaatacaatt atctcatcat catcttctct tccaggaata gttccgttta
    27181 taacattccc taaatcacca ctaaaatcat ctttacttat cttaccttct tttaatggaa
    27241 ttaatatatc tcctgactca gataaaactg catctgttga ttcaaaaaat atcttagacg
    27301 ctctagttaa acagtttggg cacaactctt gcatatctgg catatatgaa cctactgcac
    27361 ttattaaagc tccttttttc actaagtttc cattaagtac tggttgtttt gatggagtag
    27421 ctaaaactat cacatctgcg ttatttatgg cttcatcaga tgattcaact gcaactattt
    27481 tagtattata tttacttaat tttaagttca tttcttctgc aaatttttct ctactttcct
    27541 tgtttctact aaaaactctt acctcatcca aatttctagc ttctatcatg gcttcaagtt
    27601 gtggctcacc ttgtcctcct agacctatca aagctccaat cttagaatct tttttagcca
    27661 atacgtctat agctgctcca gaggctgctc cagtacgaat ctgagttaca taagtgccat
    27721 ccaatactgc actaacttct ccagtttctc catctaataa tagtactgtt gctggaatta
    27781 ctggtttgcc tttttgagca tttttaggaa atacagatac aatttttatt cccccacagc
    27841 ctaattcttc tatgtatcct ggcataaata acatactagc atcttgactt ggaacagata
    27901 tattggttct caaaggattt acactctttc cttcacaata aattctaaaa gcttccttat
    27961 cagcttcaat tgcatctctc attgtaaata ctttttttat gtcgtctttt tttaaaagta
    28021 gcatttttat acccccaatt ttaataagtc tctatgctaa atattatagc ataacattta
    28081 atttaatctt ctatttcaaa tcaaataaat ctacatactc tggttttagc atagaactta
    28141 tcaacgcttt atttattgaa aattctggta ttcctgctgc atatggagtt atatcatata
    28201 aatcaaaata tacaactaga ttctcatctt gcaaataaaa gttttgattc tcttttatac
    28261 ctttaaaatt atatattccg atattttctt catccttttt ttcaagttca gctatttgtc
    28321 ttttaatttc ttcatctata acttctttat atttagtatt atccttaaac aagtccatta
    28381 attctaaaaa ttttccagtt ctcatatcca cattatatgc tatatcttga taaaatccat
    28441 gtgctccacc actataagta taatatctca cttttatact aagagcagaa tcagtattct
    28501 ttttaagttc aaagtctaca tttgcaacaa acttattttt ctcgtcagga ttatccttaa
    28561 gatactgctt tgcttcttta tatgatttat tataaaattc aaatatgtca ttttttatct
    28621 tatcatttgt agacctttca acaattttat ttgaatttgt tattacaggc atgtttatag
    28681 tactttctaa atactcatca tttttcacta ttgttttact tcctattgta cttactgata
    28741 aagtttgttt actatttgta ttaccctttg gtaatgactg gttactcata acagtcactg
    28801 cttccttatt actatttaaa ttaattgaag catctttcct taaattatta tatttatagt
    28861 catgtttaat tgccaaaaca gccattatag tcaatgttaa aacaaataca tatcttaaaa
    28921 ctttagcttt tgtatcgact ttaaaaaatt tcatattatc attttcctcc taaatataaa
    28981 tctctcttat tatatttgga gtttctaggg ttttttatcc atataattta ataaaagatt
    29041 aatttttatt tataaaaaat taatcttttt gttttaaaat attaatatgt cttatcaaac
    29101 agtttgaaat ttcaccaaga ggtaattgta acataacaga acctctatca aaagctacca
    29161 ttggcattcc atatactata caagaatttt catcctgtcc aattgtaaat gaaccatttt
    29221 ctttcatttt taaaagtcca tttgctccat cataacccat acctgtaagt attattccta
    29281 ttgaattttt acctgctact tctgctactg aatcaaacaa aacgtctact gatggacagt
    29341 gaccacttat tctttctccc ttttcacaag ttacataata tccttgttta tctgtacaca
    29401 atttcatctg gtaaccccca ggtgcaatta acacatttcc ttgttcgact ctatcattat
    29461 tcttagcttc tcttacattc ataatacact gcttgtcaag ccgttgtgca tacatataag
    29521 taaatatagc tggcatatgt tgaactacaa caatccctgg tgttgatttt ggtaggtctt
    29581 ttataatttc aagtattgct tctgtaccac ctacagatgc gcctatagca ataaccatat
    29641 tattaaaacg ttccacatta ccgcctccaa aaaatcatat atcaaaaata cctttttatc
    29701 gtttatatat agcaggtttt acatatttgt atttagtact acttctgttg attacttctg
    29761 catgtcctac aaacaaaaaa ctatcttttt tggtagcatt ataaaattta tttataagtt
    29821 cttctcttgt ttttaaatca aaataaatca taacatttct acaaaaaatc aaatcaaaat
    29881 gttgatatga gaaatcattc attaaattaa acggcttaaa aattacactt tttctaatct
    29941 tatcacaaat tttaaatgta ccatccttgt tgtctataaa atacttcttc ttccataact
    30001 caggaacatt gttaacattt gattctatgt atatacctct tttagctttt tcaagtgagt
    30061 tagttgaaat atctgtggct atgattttaa tgttccacaa ctctttatta tatccaaaat
    30121 aatcatccaa agtcatagct attgaatacg cttcttctcc actagaacat cctgcactcc
    30181 atatatttat gtttcttatt ttattatttt cttcccaaaa aggaagtata ctattctgta
    30241 taaactcaaa atgttgaggt tctctcataa aaaatgtgtg gttagtactc aatctattta
    30301 ttaggtttat agcttcattt cctgtcttat ctttaaataa tagattcata tattgactaa
    30361 aagaactaag ttttttctct atcattgtat tgtataagcg accttcaatt aacgctcttt
    30421 ttttacttaa atcaatacca tattcttttt ttacatagtt tacaagaact ataaattctt
    30481 catctgtgag ttttatcatg caaaaacttc ctcctgctaa tttatcagaa ctaactatat
    30541 gctattaatc aaaaactttc gaatatctaa aattaatata gaattatctt caactttcgc
    30601 aatctctttt atatctttat taatattagt gttgttagaa ttagtcgtct ctagtaaatt
    30661 tagattttct atatgaataa catcaacaac tttatctaca ataattccaa cttgatactc
    30721 atcaaccttt gtaattatta tacaagttct ctcattataa tcagctttag gaagattgta
    30781 ctttatatgc atattaataa ctggtattat tcttcctctc aaattaataa ctccacttat
    30841 atatgttgga agacatggta catacgttat tgattgaaat cttatggttt caatcacatt
    30901 ttctaattct attccataaa taacatcatt gacataaaat gttaatactt gtttaataat
    30961 ttcatcttta gccatacttt aaatccccta atatatttct ataatgctat ctgcatctat
    31021 aattaaactt atacttccat ccccaagtat tgtacatccc gataaaccct tattttttat
    31081 attaaatcgg ttaaaataaa ctggaaatgg tttcacaaca acttgctgat tacctattat
    31141 ttcatcaaca aaaatgcata ctgctttatg ctcattttca ataattatca tattaccatt
    31201 catcagattg gttacttttg tttgaatatt atatatttta tgtaacctta taatgggaat
    31261 acatgctcca tatattgtaa ttaactctgt cttatttcct tctgtaatta tttgatttaa
    31321 gtctgtaagt ttaaatgttc ttcttatgga tgatattggt aaagtaaata gtgaatctcc
    31381 aactttaaac ttcataccct ctactataga aagagttaat ggtattttta tagtaaaggt
    31441 tgtcccttca tcttgtttac tttttacttc aattgaacct ccaacttttt caatactttt
    31501 acgaacaatg tccatgccta ctcctcttcc agaaaattca gttatagatt cttttgtaga
    31561 aaagcctgga gtcataatca aagaattgac ctcgtcatca gtatactcat tactttgatg
    31621 tttaagaaga ccttgttcct tagcttttgc caaaatctta tctctcataa tgcctctacc
    31681 atcatctgaa atacttatca cagcttctcc gcctagattt tcagcagata aaactatctt
    31741 tcccacttct tctttacctt tcgctatacg ctcctcaata ggctctattg catggtccat
    31801 agcatttctt ataaggtgca taaaaggttc tgctaaatta tcaattacac tcttatctac
    31861 ctctgtctct gctcctatag ttattaactc tacattttta tctaattttt tattcatatc
    31921 tcgtacaatt ctatgcattt tttgaaatac accagcaatt tgaatcatac gcatagacat
    31981 tactatatct tgcaattcat ctgtaagctt gtgtaattgt cttgttgcct tattgaaatt
    32041 atctatatca acacctgtag aatttacgct atttacaacc attgattcca taattacaat
    32101 ttctccaact atattttgaa gtaagtccaa tttttctaaa tttacactca taatactctg
    32161 cttacttatt ggtaaatgtt cattttcttc acttagacta tctttttcca tatcagtttt
    32221 ttcatttaaa acatcttctt gtatctcatc ttctgtatag ttattttgat aacttttact
    32281 tactttatta ttatctttta atttattttc tactgcatca ttgtttgatg tatttttcat
    32341 ttctatttct tttttactaa tatttatgta ttcttttaca tagagattat cttctatagt
    32401 tttataaact attgccttat cctctttagc tacaaattgt atataaaacc cataactttt
    32461 aatatactct gtagactctg catttgtttc tacatctttt ggataaaaat ctataaattc
    32521 acagtaatct ctaagttcaa atacaagcat gaaagctctc acattttcca tcatgcaacc
    32581 ttgttcaaag attattttta ctacatcaga gtcttctttg tattcaaaat ttgaatcgat
    32641 tacttctttt tcgtctttac tttctaaatt tgcattatcc tttgatttca tagaacttga
    32701 taattccaaa gtactcacat actcttcaat tccttcaata aaattagagt aatcagaaga
    32761 tatacaacct cttgattgta actcatctat atctcttctt ataaaatcta atgattgaaa
    32821 gactaaatca aataataggt cattgtctaa aacttctatt ttaccttcac gtatagcata
    32881 aaacaagtct tctacactat gtgctaaagc agatatattg tctaacccca tcatagatgc
    32941 tgaacctttt atcgtatgca ttattctaaa agtttcatta atgttgttat gagtaaatac
    33001 tttctctttt tctatttgaa tcataatttc atctaattgt tcgagtaata aacttgtctc
    33061 aaatataaac atatctaaca tttgtctcat actcggttca atataattca catttatcac
    33121 ctacgaccta caaataattt tctattatat atgcatctca taatttaaat ccttgatgat
    33181 tctcttatct cactatatgt acctcataat ttaaatacac aattattctc ttacttcaat
    33241 atatatacat ctcataattt aaatacatga taattctctt atttcaatat atatacatct
    33301 cataatttaa atacatgata attctcttac ttcaatattc acctcataat ttaaacccat
    33361 gatgattctc ttacttcact ttcctttaga tgaaattttt ctactaattc ttttaaaatt
    33421 tgagcttgag cagacatctc ttctgaggct gctgcacttt cctctgctgt tgctgagttc
    33481 atttggacta ctatggaaat ttgctctatt ccagataaaa tctgtgtaat tgctacttct
    33541 tgactatgta cagccgaaga aataccatta atataattag tagttttttc tacaccattt
    33601 actaccaagt ccaatgcatt tgcagtctct ttagcaattc tgacaccatt ttctactgtt
    33661 ttaatagctt cttctatgag aatagctgta ttttgagctg cttttgcact tttaccagcc
    33721 aaagacctaa cttcatctgc tacaactgca aatcctctac catattgacc tgctcttgct
    33781 gcttcaacag ctgcatttaa tgcaagaata ttagtttgga atgctatctc atctattgtt
    33841 ttgattattt ttgatatttc actcgatttt tcacttattt cacccattga tgtcatcata
    33901 tcatccatac atctacttcc aaaaccaact tgtgatgcag attggtcaga tacctcacat
    33961 gcaagactag cactatctgc acacttctta attccatctg atatctcatt aatcgtggaa
    34021 gctaattctt ctactgaact agcttgttca gtagcaccct gtgaaagagc ttgtgcacct
    34081 gctgcaactt gttctgaagc acttgcaact tgctctgctg ataaatttat ttcagaaaaa
    34141 tcaccattaa aagagtttat tatactttct aaagatattt taattgattt aaaatcacct
    34201 ataaattctt ggtctatctc tactcttaaa tctccttttg caatactagt taatgtactg
    34261 tctataaggt ctatgtaatt taaaagcata ctttgcatct ttttgacaga actcactaat
    34321 agccctattt cagatttact ttcttcaacg tctatacttg ttcttaagtc cccagatgca
    34381 attcttgaaa agtgtttttc tactttatta ataggaatca ctatttttaa ttttattact
    34441 gtatattcta ttattgtcaa tattattaaa agggaaagta taaatattgt tcttaatatt
    34501 agactttgta attctttttt tacctctaca attttggaat ttgaacgggt aactatatcc
    34561 tcttgaaatt catttattaa agaatccatt ttctcttggg agtttatata gtcactacca
    34621 aaaattatac tttgagcttt actcttatca ttactttcga ctgcctttat tgcactttgt
    34681 tctgttggta ctaaagaatc tgatatttct tttgcttcta agattttatt tgactcgctc
    34741 tttgtaagac caattttttc taatttgttt aaagctgatt ctcttgtttt tccgtataat
    34801 tctttttcat aaatatcttt attctttttt tctcctgtaa atacatatct tcttaataca
    34861 tcacttatct ctctagttgt atcttttata tactgacttt gagtcctcaa attattcata
    34921 tcattaatac ttttttctac tttttcaaat gctttataag atgaaataga agaaaaaatc
    34981 cctgctagaa cagccaatac tataataatc agcaatacaa ttgctaattt agaaagcttt
    35041 acttctcttt tcatatctgt actccttcat aaagtaagtt tatatctttt ttaatccttt
    35101 cattgtactc actacgctac aatcttttcc taagttttta ccctcataca ttgctttatc
    35161 tgctaaggat atgttttctt ctaatgatat atttgagttt acttctacta ctcctaatgt
    35221 aatagtgcac tttattttat gttctttata gttgaaatca aactccttta tctctttacg
    35281 gattctttct gaaagtatct tagcaccttc tattggagta tttgtgagca ttatcaaaaa
    35341 ctcttctcca ccccatcttg atacagtatc aatttgtcta caattctttt ttattatact
    35401 tgatattact gttaacacga aatcccctgc ttcatgccca taagtatcat tgataacctt
    35461 aaagtcatca atatcaccaa ggataaggga tattgatgtt tcactatatt tattaattct
    35521 tctttgctcc ataagctgat taattatatg tcgcctattg taaagacctg taagataatc
    35581 tcttacaacg agtctattca atttttcaag agaagattcc agttcattat ttatcttttt
    35641 taatttatct tgagatttct ttacttcaag atgagctata acacgagctt ttaattctgt
    35701 catactaaaa ggtttcacca tatagtcaat tgctcctaca ccaaatcctt ttactatgtc
    35761 tgtatctgta ttttttgaag ttataaaaat tataggtata tctgctgtac gagcattaga
    35821 ttttacttcc ttacaaaact caaaaccaga gttatctggt aaaattatat caagcaaaat
    35881 aatgtctggt ataaattctt caataaattc ttttgcctct attgcattaa atgctttttt
    35941 aaccttaaaa ttatcttttg taagtgtttt atctattaag tcacacatca gaacactatc
    36001 atcaacgact aaaattgttc cctgttgctt atttttcata tacaaacctc tcttaaacat
    36061 aatatattca aattttaatg atttaaaatt tttatactta ataattatac cactatattc
    36121 ttaaatgttc tcatcacaat ctttttataa taacactcca actacatccc tatgttacat
    36181 gatagtgcaa tcaaacccat tgattaattc atctattaaa acttcatctt tatctgtcaa
    36241 aagtttctct aaatctagta aagtaattat tttaccttct aattctccaa ctccacttac
    36301 aaaataatcc gaatattcta tagtaactct tggtggaggt gatattttac ttttttctaa
    36361 gcttactata tcatcaactc tatcaaccac aaatccaact accaagtcct ttatttcagt
    36421 tactactata tacatgcaat ttgtagtcat taattcatct tttttaagtc tcaaacgcat
    36481 gtctattatc ggaatgattt ttcctcttag atttattatg cctttagaat atgtaggtag
    36541 ttctggaata aatataattt cttgatttcc agtaatttct attacctttt caagttcaac
    36601 cccaaagtct tgctcatcta ctctaaactt tagatactta attccttcat caattagtcc
    36661 ataatctaaa tatgggtcat ctggaaatct catttaatac ctccctccta aaatacactt
    36721 tctatgaaat atatattata atttcttctt acctttattt attgaatcta caagtaattc
    36781 acccgtctca gtgtaaaaac gtattgttct accataattc atacctgtgt cctcagctaa
    36841 tattggaata tttaatccta aaagagtttt ttttactgcc tcaacattcc tatgtcctat
    36901 acttgcaatt actgaattgc tacttcctaa aaacatctga gcacctccag caatttttgc
    36961 ttttatatat attctatttg cacctatatt ctccatagat ttaatgagct catttattcc
    37021 tgtgtcagca aatttacact tattttcaat gttaatagca tctttactat atggcaacat
    37081 aacgtgtaac attccaccaa ttccagctac tttatctatc aaacatactc ctacacaaga
    37141 accaagtgca taagtaacta aaacatttgg tctataggct atcttcatat ctgcaatgtt
    37201 cactactatc tctctattca tacttctaat cccaacctca cgagtatttc tctaagtgag
    37261 ctcatttctg gaatcatcaa aatgtgacta gtaaaataat tatcactcat tttaaattta
    37321 ttttctataa ataagacttt gtcaccaaca tctgaaaatc ttatcatagg tacatttaga
    37381 acagctccaa ccatatcaat acatatatct ggaattgaaa cacttatagt catgtttaac
    37441 atagatgcaa tagcatttac atatgaactt gccataatat ttcctatttc cttaattgct
    37501 gaaatttcaa ttgcctcaat ctcatctaaa aaagcttctt ctttattaaa aagagaactt
    37561 agcataagtt gagttattga ttcatccaac aaaaacataa acattccatt gatatcacct
    37621 ttcatatcga gtaaaataca tactactttg ttttctggac caccaagcaa atttgtcgct
    37681 tcattatatt caagtatctt gaccataggt attaatactt ctacattgct atttatcatg
    37741 gatgcaagtg cagtaattgc attcccagag cctatattac caatttctct aagagcatct
    37801 atatgaacat catcaagttc taaataattt ataatataaa cccctccctt tattattgca
    37861 tttatttgct tttcattgta ttagtgtata tttacacttt tattttaaag cattatctac
    37921 aactttaact aatgtttctg ttttgaaggg cttcactata aaatctaacg ctccaagttt
    37981 tatggcttct acaatcatat tctcttgtcc tattgcagag cacattacaa ccttagcact
    38041 tgaatccaac ttttttattt ctcttagcac ctctaaacca tctttttttg gcattgtaat
    38101 atcaagcaac atcaaatcag gcttttcata tttaaatata ttacacgctt cttctccatc
    38161 atttgcttct attaaattat tatagccact tttactcaga gcttctttaa ttatcattct
    38221 cataaaaata gcatcatcta ctatcaaaat tttattttcc ataaaactaa ctcctccata
    38281 tgtacaacaa taaacgcttt tatcttcagt tattgtctat actatctgac tatttttcgc
    38341 tacacaataa atacatttca ttgataaata aaagtaatta tttatgccat attatactta
    38401 attctcttaa cataatttgt caacaaaaaa acttatatat ctattgtaat atatgtttgg
    38461 cgttttgacg agttattaaa aatataattg tataaaacat aaaaagttat caaaagtaat
    38521 taaattataa taaaacaact ttataccttt tttatgtttg tataaaaaaa tttttcagat
    38581 tcattaaaat catttctgta gattcatata ggatttgact ttctcaatat ctaatagata
    38641 gttgtttatt tacttaatta tatttctcta tatgtattat cgattaaatt agatttagct
    38701 ttatacatta ttttttatat ttttcaaatt gtatactcat aaatccagaa gtattctaat
    38761 gtgtttataa tacttttttt catattttaa attaaataac aaatcattat atttacaagt
    38821 atcatttatc aataaacaat attaaatgaa gaatatgtct gaagattcaa agtgatactg
    38881 ataatattaa ttactaaaaa agcagtaaat cttttacaga tttactgctt atagttataa
    38941 ataataaaac tatctataat aaatgtacta tactcaatac ttcattcaat atagtaataa
    39001 caaatctact ttattcctat ataaatatga acttcttgtt tctttgtatc aaaagtatta
    39061 cattgatact cttcaaaatc acttatataa gtcctatcaa aatccatttg ccaaaactca
    39121 aaccaaaaat ctcctacttc tttttgacct cctactataa caaactttgc atacttacct
    39181 gctggtataa ctttactaat aatactttct ccaacagtat tattagtgtt taattcttct
    39241 aaattcttct ctttatcaga attactattt acttcacaac atgcaacaaa gctatacgga
    39301 cttgtaaaat caccctggta atctgtatat agacctattg tcttgtcatt ctttttaccc
    39361 tttatagcat tatatatccc tttgcccata aattttttcc acaattcacc tatatcattt
    39421 accgcttgtc catctttatt tgtagtctcc ttcgatattc ctataactat tttctcattt
    39481 atctctacta tttcataatt catactttat acctcacttt gtttttatta atatatttta
    39541 ttttgaacta attcaattat aatttataat atacgacacc tttatgtcat atttttaata
    39601 taattaaact cagtgagata ttatatacta aatgcaagat attatatatt taataaaatc
    39661 tttaatctag cattatatta taatgaataa attttagaca actcccttag tctagttatt
    39721 acattatccc taacatcttt aggttcaagt acttcaacat tgtcaccaaa tgataaaata
    39781 tatccataaa tccattcacc aataggaaat tctgtaatta catcatatgt atcatcttca
    39841 tttttagtta ttaaatcctt attaaaatca tcaaatactc taaaaagcat cttttcttta
    39901 aacctcaatt tcaacgttat agtattttcc ttaattactt tagaatcatt caaacatact
    39961 tcttctatta tctttcttga aaatacttca tcctttatag ataaattcct tatcctacta
    40021 attctaaata tcctaaaatc atcttttagt ttacaaaatc catacaagta ccaagtctta
    40081 ctcttataca taagcttcag tggttcgaca gttctgtttg tctggcttga caaactattt
    40141 acataattaa aatttatagt attacgcctt aaaatagctt cttttatttt tgtaaattta
    40201 tcatcttcat taaaattact tccccattca gtaaagtcta tttcaatcca gtttgaaaaa
    40261 ttctgctctc caaatattga gccaatttta tttactactg aatttatttc tggatactta
    40321 gtcgcctgta atgttttcag tgccactatt aaactctctt tatctttttt tgacaatata
    40381 gccttgtcta tagaatattc ttctattaaa gatatccctc ctcctttgcc tttcgtcata
    40441 tatactggta ctcccgacat agacagagtt tctatatctc tatatatggt tcttgtagaa
    40501 acttcaaatc tatctgccaa ctctttagct gttactaatt ttttatttaa tagaattact
    40561 attatttctg ttaatctatt tattttcatt cattaccacc tactaaaatt attaaattta
    40621 tttaatctaa attaatcata ctaattttta aataaataaa atcttagaat cttatctaaa
    40681 ttattcttac atgattttat ttactttcta ttatctttct cactttggat attatcatct
    40741 taatttattt attactatat caatttactt attatcatct catttgttat cgtcttactt
    40801 aatttactta tttctatatc aattcactta ttattacctc acttgttatc atcttactta
    40861 atttacttat ttctatatca atttacttat tatcatctca tttgttatcg tcttacttaa
    40921 tttacttatt gctatgtcaa ttcatttatt attatctcac ttgttatcgt cttatttaat
    40981 ttacttattt ctatatcaat tcacttatta tcatcttaat tcatttgatt attatcattt
    41041 actttattca atttctatat caaaaattag tatttgtact taatacttaa aattaattta
    41101 aagtctttac atattattta ttttttattg taatattaat ttccatactt tgctaagcta
    41161 cttccactca tttattttaa aatttcaatt tactatttct caattctata ttattatttt
    41221 tcaattttat attactaatt ttaaagcttt ttagctatta ttcctacaat atttaaacaa
    41281 ttttttaata ataaagctat attacaatat attcaaaata tgtaatattt tagatatttt
    41341 tcgttgacaa tgttaaattt ttgttttatc cttaattaag gacatgttat tgacatttct
    41401 gaaacttatt tgaaatagtt ttttcatttt atttaggaaa acgtattata cctaagaaaa
    41461 cgtattttct catttcagat aagtaaaata tttattcttt tggggaggaa atcatggaaa
    41521 ttaataaaaa acattttatt caagtatttt taacttgctt aatcttggta gtaatatgtg
    41581 aatttatagg gcaaagaact atagctattg gaaaagcctc tatagtactg ttccctatgc
    41641 tttatgcagt tataattgga cttataataa caccagattt attaggtaaa aaaattaaag
    41701 cacttaaaaa agtggttgga gaaaaagaaa taaatattgc tggtgaagtt gttggaattg
    41761 cactagtaat gcttggtata aaatatggta ctacagttgg accaaacatt gacaaaataa
    41821 ttcaagctgg accagcattt atcgctcaag aatttggtca tatacttgca ccaatcgttg
    41881 cattacctct tgcattaatg tttggaatga aaagagaagc tgttggagct actgcaagta
    41941 taagtcgtga accttcttta ggagttatat cagaaaaata tgggataaac tcaccagaag
    42001 gtagtggtgt acttggtaca tatttaatgg gaacagttct tggtactata tactttagtg
    42061 tactaggttc aatatctatt tatagtggtc ttcacccata tgctttggga atggcctgtg
    42121 gtgttggtag tggaagtatg atgacagcag ctgctggttc attatctacc atggtaccac
    42181 ctgaaatggc agatacaata cttgcctatg ctgcaacaag caatatgatg tctagtataa
    42241 caggaattat attcttagtt tttgtatcct taccatttac taattttatg tataagattt
    42301 tagaacctaa attttcgaga aataaaaaaa ctaaagaaat taaatctaca gaaggagagt
    42361 gctaataaat gtttgctaat ttaaatttaa agaaaagttc atatcaatta ttggttatgt
    42421 ctgttattgg agttataatt cttataggac aaagaattag cgttggtaca tctatagtta
    42481 cagctcttcc tggtatggtg atgctaatat tagctgctat ggcagctatg attataaaag
    42541 atttatttcc taaatcaatc tttccagctt ttggatttgc aactataatc ggccttttac
    42601 ttagtatgcc atatagtcca acatctgaag tattcttaac taacactaat aatattaact
    42661 ttatggctat aactactcca ctactagctt ttgcaggaat ttctgttgga aacaaaatag
    42721 aagctttaaa agaaatgtca tggaaaatag ttataatttc acttattgta tttacaacta
    42781 tattctttgc atgtgcgagt atagctcata tagttttaag tattcaaggt aaaatatagg
    42841 aggaatttat tatgaataaa gaacaattaa aatctctagt aataaaaact atagatgaaa
    42901 atagagaaaa aatattaaaa ataggtcaag gaatatacaa aaatccagaa tatggatata
    42961 aagaatttaa aactacagaa gctgtttcaa acttttttga gcaagaatta aatttatctg
    43021 tagaaaaaaa tatagcagtt acaggatgca aagcagatgc aaattctagc aagaaaggtc
    43081 ctcatatatc tatacttgga gaattggatg gtatatcatg taaagaacat aaagatgcta
    43141 atgaaatagg tgcttctcat acttgtggac ataatattca aatagctgga atgttaggtg
    43201 ctgctgttgg tttagtaaaa agtggcgttt tagaacattt agatggtaaa gtatctttta
    43261 tggctactcc tgctgaagag tttattgagt tggaatacag agagcaatta aaaaaagaag
    43321 gaaaaataac ttattttggt ggaaaacaag aattaataaa aagaggttat tttgatgata
    43381 tagacatatc tatgatgttt catgcttctg atttaggaga agataaggct ctagttggtc
    43441 ctgagagtaa tggatttgtt ggaaaaaagg ttaaatttat aggtaaagaa tctcatgctg
    43501 gttctgctcc acatgatgga ataaatgctt taaatgcagc aatgcttgct ataaacaacg
    43561 tgaatgcact tagagaaact tttaaagagt ctgaaagagt tagattccac cctatcatca
    43621 caaaaggtgg agatatagta aatgttgttc ctgctgatgt tcatatggaa tcatatgtta
    43681 gagctagaac tataaatggt atgattgatg ctaatgaaag aataaataag gctttgatgg
    43741 ctggtggaat ggcagttgga gctgatgttg agataactga aattcctgga tatcttccaa
    43801 tattacgata caaaagtctt gataatttat ttaaaaacaa tcttgaagat ttaggtctaa
    43861 aaggaaaagt tattgatggt ggagatttta caggctcttt tgattttgga gatgtgtctc
    43921 atataatgcc tactcttcac cctatgattg gtggtgtaaa aggagctctt catacaagag
    43981 attttgaaat agttgatgaa gatttagctt acataattcc tgctaaagca atggcactta
    44041 cagttgtaga ccttcttttt gataatgcta aggatgctaa agatatatta gataccttta
    44101 ctccagttat gactaaagaa gaatatctaa cattcttaga aaaacacgat aaaactttat
    44161 aagtctattt ttataatagg gtggtatcta ctgtaaaagt tataccactc tttgtttttg
    44221 taacagtata cttcttttct tttagttttt agattaaact aagatatatt atcctcctta
    44281 aaacttttag agctacgttg aaatatcagt agaactatgc tatattcttt ctaattaata
    44341 taaatttcta ttctaattca aggtggtgaa aaaatgttta atgcaggaaa tcgaattata
    44401 aatacatggt tgtaccctat tcaagatggc tttgtcttga ttgatactgg atatgaaaat
    44461 ggttttaaac atttcaaaaa acgaatttct aaattcaaca taaaaatcaa agatattcga
    44521 tacatatttc taactcatgc tcatgatgac catgttggtt ttctaaatca gattctagac
    44581 gaatctccta atacaaagat tgttatgcat gataaagctt tagaaattct atataaaggt
    44641 caaaactctt ttattggtgg ttgtaccagc cgtactgcct ttctcttttg ccaaattatg
    44701 aaactatttg gaaaaggtga gcatagtttt tctccactta aacaagaatt tgaaaaaagg
    44761 tgtattcttg tgtctgacaa gaatcgtaaa gaaattgaaa aagaactaaa tggaaaaatt
    44821 atagatacac caggacatac tgctgattca atttcactac taattgatga aggtgtttta
    44881 ttttgtggag attctgcaat gaatggattt ccaagtactc acaaaattac catatttgca
    44941 gaaagcaaac tagaatttat tcaatcttgg aaaacaatca tcaatacaaa acctaaaatg
    45001 atttatcctg gacatggaaa accatttgaa tacagtaaat tagaacaaaa tctaatctat
    45061 gtaaataaaa taaatttata tcctctacat aattcaaaag atattcacag gtttttgtag
    45121 aaaatacaaa gtaaatttat ttgattaatt aaaaaatcta acactttact acgctactta
    45181 ttttaataac ttaatcttcc actagctttt cataaaattt tgttttaaaa ttaattttaa
    45241 agcgcatatg ttatttaaat acattagata aaattcgtca ttaatctact taaagcatat
    45301 ttaactaaca ccactcaacc agaaaattca gaaaactgca ttgacacagg aaaaagttta
    45361 ttttatactt tttttaggac atattgtgga cacgtcttaa atcgacaaac agaatttaaa
    45421 ttgtaagatt aaccacaata cttatttttt aattatattt ttaaacatta gggaggatat
    45481 tatgaatgat aacgtagtta agaagaaaaa cttttttgac aggacattaa acagaataga
    45541 aactgttggt aataaactac cagacccagt tacaatattt ttagggttat gtgtactttt
    45601 acttatacta tctagtctag ttggttctat gggtatatca gtagttcatc ctggtactgg
    45661 agaaactata accgctgtaa atttattgac tgtagaacag cttcaaattc ttttaggaaa
    45721 catagtcagc aatttccaag ggtttgctcc tttgggtcta gttctagtaa ctatgatagg
    45781 tgctggtgta tgtgacaaaa caggacttat gacagcaaca atcaaagcat cagtaagcaa
    45841 gattcctgaa acaagagtaa ctcttgttgt aatgactata ggtatgcttg ccaatatagc
    45901 ttcagatgca ggtacaatat tatttccacc attagctgca cttgtatatc ttggtgttgg
    45961 tagacatcca cttataggtt tattttctgg atatgcagca gtctgtctag gatttgccgc
    46021 aaacattatg ataagtgtca atgatatact tgctgcaagt tttacagttc cagcagctca
    46081 aatgattgat tctggatttc aagccaatgc aacaatgaac ttatttttta tgatagcatc
    46141 aacttttgtt ctaatacttt tggcaacatg ggtaacagaa aaaattgtag ctcctagatt
    46201 tggtaaatat gaaggaaatg cagaactaga tgttgatgga agtcttagtg atgtagaaaa
    46261 gaaagggctt aaaaaagcta gtataagtat attaatatat gtggctatta tagtagctct
    46321 tagtgtaatc ggtaaaaaac cattcttagc tgacccagaa acaggagatt tactatcaaa
    46381 caatgctcct cttatgaaag gtatggtacc tataatagca ctagcatttt tcatacctgg
    46441 tgttgtatac ggaaaaacta taggtaaaat aaagaaggat aaggatgtag tctctataat
    46501 ggctagtgca atgagtgata tgggtggata tataatacta gcatttgctg cttcacaatt
    46561 tttgcaatta ttcacaaata gtaatttagg tctgatacta gctgtaaagg gcggagaatt
    46621 tttaaaatca gcaggaataa atggaccttt attgttgata ggatttatta tattatcatg
    46681 ttttataaat ttatttatag gtagtgcatc tgcaaagtgg gctattcttg cacctatatt
    46741 tgtaccaatg tttatgatgg ttggatacaa tccagcactt actcagatgg cttatcgtat
    46801 aggtgattgt ataacaaatc cacttagccc attatttccg tacttcccta ttatactagc
    46861 attcacaaga aaatacgata aagatgctgg tatgggtact gtaattgcta atatgatacc
    46921 atactctata tcattcttaa tagtgtggac tatactatta atattgttta tggtatttaa
    46981 tattccacta ggacctggaa tacttccttc atatagcatg taatttattt aaatctttct
    47041 aaaaggagaa ataatttatg ttagataaaa atagacttat aaataatttt atggatatgg
    47101 ttagaattga tagcccatct aatcaagaat tagaaatgtc taagtggttg gtaaactact
    47161 taaaagaaag aaatatagac gccattatag atgatgcagg tgaaaaatat ggtggtaata
    47221 caggtaatgt cattgcctat ataaaaggtg aagaaggaag tagaccactt tgtttatgtg
    47281 cacacatgga ccaagttcaa ccttgtttag gtgtaaaacc aatactagat ggtaatgtag
    47341 ttagaagtga tggaactact acacttggtg cagatgataa agctggaata gctgctatac
    47401 ttgaagcttt agaacatgtt attacagaaa aaataccaca tagagatatt tatctttgtt
    47461 ttacaatctg tgaggaagcc ggtatgcatg gtgtcaaaaa ctttaatcct gacaacttgc
    47521 cttgtaaaga catggtgatt ttagattctg gtggagctat tggttcgata gcatacaaag
    47581 ctcctgctca acaatctata aaaatctctt ttcatggaaa gaaagcacat gctggtatag
    47641 aacctgaaaa agggttaaat gctatattag tagcctctca tgcaataagc aacatgcaca
    47701 taggcagaat agattcattg actacttcaa atataggtaa aatagaaggt ggtggagcta
    47761 caaacatagt aactgataag gttacattga ctgctgaaat taggtctcat atacctgaaa
    47821 ctttagagta tgagcttaat catatggaaa aatgttgtaa ggatgctgca tctaaattta
    47881 atactactta tacttttgaa catagtatgt cttaccctag ttttgaactt agtagagata
    47941 gtcatgtttt caagttaagt gaagaagcaa taagacaagt tggtgttgtt ccaaatccaa
    48001 tggtaattgg tggtggaagt gacgcaaata tattagctaa tcttggatat aattgtgcta
    48061 tattaagtct aggtatgtat gatgtacaca cagttaatga atatgtaaat atagacgaat
    48121 tatatgatac tgccaaaata gtttatcata tgattaaatt ataaatatca taatataact
    48181 ctttaaatta taaaaataaa aacctatgta tcttcaactt tataagttat atattaaagt
    48241 tgttttacat aggttttagt attttatata ataatttgtt ttaacatttt tcataataag
    48301 cttcaatatt ttgcataata atttgttcta gcatttttaa taacaagctt tagtatttta
    48361 tattaataat ttattctagt attttacata atcatttgtt ctaatttttt tcataataag
    48421 ctttaatact ttatatagta atttgttgta gaattttata caatataatg atttatacag
    48481 ttttataaaa tatcttaaaa cagtatttca gtaatatttt ttggtcttcc tccaccaata
    48541 ctagtctctt ttgcacatat tcgacctaaa cctgcattta ctattttatt taatatacgt
    48601 cttgcacttc tttcacttac atttagatac tctgctaact cttttgaatc ataaatctta
    48661 ctttttctat tctcatttat agcaataatt tttgcaactg actcacaact cattccagtc
    48721 tttttagata tttcgattac cttttcatca gatagcatca aagaataatt taattcattt
    48781 tcggaagcta aaggtcctct tatgttttca tcttcatcta ccaaatatat accaatttct
    48841 tttgaatcta tggagtgtct taatgcttta tgtgcattat tttcagcctg atacgcagtt
    48901 actccagtac caattcctat actaagagaa aagcccatgt cttttatctc tctctttaga
    48961 ttgaatagct tatcataatt atactcatta tcagctaccc ctttatgaac aaatacaaca
    49021 taatcatttc ttccaagtaa aaataaggaa ccttgaatac ttcttacata gtttactaca
    49081 agcttatcca tatctgattt ttttatcatg tcagaataat agttatctat cttctcttta
    49141 taatctatta aactcaatat ttcaacagca atttgagaaa atcttgcctt acttagagca
    49201 tattcactct ttaccttgtc ataactttct ttgattaatt gtatagtagc ttgtaaacga
    49261 aatacaggat agcctctttc ttttaattca ttatatactg caccaaaacc agttaacatt
    49321 atatccgtct tattttcttc aaataatttt atatgccatt ctacaagttc agactctcct
    49381 acttccaaag aaaatggatt acaaaataca ctcgttgctt taatatcaaa ttctttaagt
    49441 gcatcttcca caacatatct atcaactaca tctatactga atttatctaa ttttatattt
    49501 gcacttttta ttgcccaaaa tgccttcatt atactcgtcc cacttctcgg tacaaatgaa
    49561 tgtggcttac ttatctcata cttagatttt ataaattcat aaactgcaca tcctgtaaat
    49621 ataatagcat cacattcgtc ttcacattta gaaataactt ctattgtatc tactactttt
    49681 tctcttacat atattttagt ctttaaatca ctgtctatct gttttaaatc atcctttatc
    49741 ttaaacccag agtctgaagg acctataata cccactatca taaacttcgc tcctaatcca
    49801 taaatattat actttttaaa aattatatcc tcactatttt ctacttctat ttaattattt
    49861 tgaactactc catcctacct acatttagaa tggaataatt agcttatttt tgataaagta
    49921 acttctcaaa atcagaactt ggaataggct tacaataata ataaccttga attaccacac
    49981 aatctaaact cactaaaaat tcagcttgtt cttttgtctc tacaccttct gccactacat
    50041 ccatatctaa atcttttgcc atggctatag tgtgctttaa aactattttt tctctgtctg
    50101 tgattccttc ctcattaaag aaaccacaat ctatctttaa tgtatcaata ttaatatttt
    50161 ttaacatatt taatgaagaa tatgctgaac caaagtcatc catatttaaa acaataccat
    50221 ccattctaag gtcggctatt atcttagtaa ataattttat atttttaata aataaacttt
    50281 ctgtaagctc taattctaaa aaagattttg gtatactata tttatttatt aaacttaaaa
    50341 caatttcttt aaaatgtgga ttatgcaaat gtaatcttga tacatttaca gagataggaa
    50401 ctggctcttc acctaaatct atccattttc taatcaaaga acatacttgt tcccatacat
    50461 acatatctaa tctgataata aacccattct tctcaaatag tgaaataaat ttaattggag
    50521 gtattatacc tttttctgga tgaacccatc taaccaatgc ttctgcacca acaattttat
    50581 ttgcattaag attatactta ggttgtaaat atacatggaa ttgcccattt tcaagtgcgt
    50641 attccatttc cctttccatc tgtttttctt caagtgcatc atttcttata gtatcatcat
    50701 aaaatatata gttgttgata ctttgtttct ttactttttt gtgagcatat cctgccattt
    50761 cacacgcatt tgtaattgga atatgattat ccaaaattct ataaacccca aaacatggta
    50821 ctaacatata ttcaaatttt tttctattta agctattttt aatcttataa attactttat
    50881 gaatatctct atcagagtaa ctctcataaa aaatgcaaaa tacatctgca tacatacgac
    50941 aacatatacc attagaacca atgttttttt gaatcaactc tgcaacatat attaaagctt
    51001 tatctcctcc tctaactcca taaatgtcat taattacctt gaacttatct atatccatca
    51061 ttataattgc ataacgcttg tcaggatatc ttttaagcat taaacttatt tgttcacaaa
    51121 aactttcata attgtatagt cctgttaatg tatctttttg gtttttatgt agttgcataa
    51181 gataatctat attttttata gcaactaaaa tatgtgtttg tttctcacct aacttatttt
    51241 tactactaat ctttaacata taaattaatg cccaatagta ctttttatct attcctaaac
    51301 gtctatactc aaaatttagt tctaaatcgt cttgcttgct attattaaga ctatcaagag
    51361 attttagaag gtggttatca ttaaataata ttatatcatc aggatgaatt aaatattttt
    51421 ttatgtatga aaaagttttt tcaagatttt cctttatagg aaaactaaaa atattgctct
    51481 ctgattgata aattggagta attaaattcg tatcaatgca aatagataaa attatatcat
    51541 atgtattata agctaatttt tcataagctt tagaataccc ttttatcatt aaatcatcaa
    51601 aataaacctt atcaactaac tctttatgtt taaataaaat attattcgtc gaatcagcta
    51661 agtcactaat tactttcatt tcattatttc taagtttgtt cttattataa tacctcttct
    51721 tatcttggta cattctctca tcagcaactt taattagctt atgtatatca atattatcgt
    51781 cactccaaat actgcccact gctacactat atatcatctc atccttaaat tcttcactta
    51841 accaactcac taattcttca aatagttgtt ttgatatatc ttcacataat acaacaaact
    51901 catctcctcc aatacggtaa acattataag aatgaaagta tttttttatt attacacatg
    51961 ctgacacaat agcagaatcg ccattagcat gtccaaagtt atcattaata tcttttaacc
    52021 catttatatc tacaaataca actcctatgg atttaacttt tcctttttga aaattatcta
    52081 tatacttaat atatttattt ctattatatg caccagtcaa gaagtcatag tagctcatat
    52141 aatttaattt attttctact tttctttttt tcatctcagt taataaaaaa taagataggg
    52201 atgtcaaaag agaggtatct ccaacagctt tatgtggatt atcaactcca ataaacccta
    52261 ctactttatc atcttgtttt agtgaagatg tcattaaact ttcaattttt tgaggtttta
    52321 aaatttcata ttctattggc tgttcttctt ttatattttc tatatcatca attattacaa
    52381 aacctttttg ttcgaataat aaaaaccaat tctttaattc attaatatca agatttgtta
    52441 gtgcctgttt ttgttcatca acaccttcat tgcaccattc atatgtatta gttacttttg
    52501 ttctatcttc tgatacttca aaaacatatg ctctatcagc tttatgaaat ttaccaatat
    52561 tggttaatac aagatttaca gcatcagaaa aattagattc tgttataaga tgtttaatac
    52621 atccaactaa taactccttt atctctaatt tttctgctat tgacttactt atatcttcct
    52681 tttctgtaat atcaagagct atttctaatc gtgcatgttt gccctcccat ttaattaact
    52741 tgtcctttaa tataaaatgt ctatttgttc gagtattcgt attttcccat atgtaatatt
    52801 catcttcttt taaaatagag tttgtacaaa attcgcaggg agaatctttc ccctgtaatg
    52861 ctttataaca ttttaaatgg gatatatcat taagtcccat tgcctttttc ccaatttcat
    52921 taatatataa aagttcatat gtatctaaag aagaaacata tacaatttca tccaactcat
    52981 ctattaaatt tattacatcc atttatatat atctcctttt attcattttc cagattgaat
    53041 ttttaaagct tttaaaattt tgctatatat ttggcaatga tattatactt ctttatgttt
    53101 taaaatagta ccttaatgag gttctatttt ttagtaaata gaattattat tgtgtcaatc
    53161 gtacaataga gttttgtaat acttaattta atatatttat aattaactat cttattatgt
    53221 atttacaatt aattctcata taaatgacaa atctccacct caattaagta ttccaatcat
    53281 atatgaggat aatacttcat tcatttaaaa atataaaact attatatatt aaaatttctt
    53341 caataataaa ttatttagat tgttactttg atatattata taatatcaca aaggctgata
    53401 taaaaagaca aaaagggcaa tttttttata tcaaaaaaaa tgttaaattg atattatcca
    53461 tatataaatt gatattatcc atataggtgc tatatttaac aattctactt acttccctta
    53521 cacttattag catatagtta ttaagagttt gttgcaaaac aacacttagc acactttaaa
    53581 aagtgtggtc taataagtaa tcaacgaaga agacataata aagcataaaa taggatatac
    53641 ttttccacgt catcaaaatt gaggatttta ttattaatat atgataaaat atgcttaata
    53701 aattaaattt taatgggaga atagttatga aaatatttag tttcttgttg tttgtagtgg
    53761 gaatatgttt ttgtattgct ggatttatgg ggcattcctc agctttttct ggtgcaacat
    53821 tgagtttttt tgcaactaca atgatagctg taagacaagt caaaactaag aaaaaatgaa
    53881 ataggcaaat cctaacttta taagttaata ttacataagt aattagtcta aaattagata
    53941 ctttttctat tacaaaaata catcatccac tttgtattct cttaaaaaaa ataaaatagc
    54001 tatgtaaatt caagattaga tagactaact ctctatccat ttcattgtaa aatatacata
    54061 gctatttgta ttcgatttaa aatacttaga ttttcttaca taacaaataa tttctatctg
    54121 attattactc atgttcattt attaaccact cagcaactaa tcatttagta tctattcatc
    54181 cgccatacgg taacctaccc caacctcagt caaaatatat tctggctgag caggattctt
    54241 ttcaattttc cttcttatac ttgccataaa aactctaagc gactgatttt cactttcata
    54301 gtaatttccc caaactttat ctattataaa cttatgggtt aagactcttc ctgaatactt
    54361 agacatcaac tcaataatct tatattcgat tggagttaaa tgtatttctt caccattaat
    54421 tgacacaata tgattttcat aatctatctt taggttttta acttcaaaag actttggagc
    54481 atcattattt atattatcct gttgagcttt atttctaaga gccacacgta ctctagccaa
    54541 aagctctgtt acactaaaag gtttagttaa ataatcgtct gctcctccat ctaaagcttc
    54601 caccttatct ctctcatgct ctctcgctga aacaacaatt attttattag tctttgcaca
    54661 tgccctaact cgtcctatta cctcaatccc atcaatatct ggtagtccta aatccaaaat
    54721 tatcaaatct gggtcaagag aatgtataag tgatatagct gttcctccat tatctgtctc
    54781 tacacaccta taattttgag tttcaagaga tacttttata aatttacaaa ttggcttatc
    54841 atcttctaca attagaacta atggctttat ttccacttgt ctttcccctc ctcatcatac
    54901 ataggtatgc taaatctaaa tgtagctcct ccagaaggat tattaaaggc gacaatttct
    54961 ccaccatgag cttctactat agatttacat atctccaatc caagaccaat acctcttctt
    55021 tcaagatttc tagacttatt cttagtataa aacctattaa aaatattccc gatatcttca
    55081 tttggtattc cttttccatt atctgcaact tcaaatagta cttgatttga ctcttttttt
    55141 acagttagtt ctatcttaga atttttaggt gtatgcctta tagcattatc aattagattt
    55201 actaacactt gttctattaa taatacatcc acatgaacga ttattatctc atctggaata
    55261 tttgttttta tgtctctact attggcaaac tttttgactc ttaatataga ttcagctatt
    55321 atttcatcaa caacctctgg tcgtttttca atatccaatt ttccttcatc tattctggtc
    55381 atactaagta tattctcaac agaatgagtt agccaactcg tatcttcata tatatttttc
    55441 aataattcta ctctagtttc tttatctatc acatcatcat tttcaagtat tgttgaagat
    55501 gaacccaata tacttgtaag tggagttctt aaatcatgag aaattgacct aagcaagttt
    55561 cctcttaacc tctctctctc tgcctcaagg tttgcttttt tatttttctc aaataaattt
    55621 tctctatcaa ttgccaacgc aacctgtgtt gaaactgctt ctaatagtat cttttcattt
    55681 tctgtaataa tatctatctt aaaacacgca acacctataa caccaagaac atttgattct
    55741 tgacctttta tagggaaata atatgcactg ctgtttttac aatattttgt cccaattcca
    55801 actgggttac ctgtcctaaa agcttctttt atagcttcct tttctaatac tgaatggaat
    55861 atattctcac ttccatcatt gttacaaata taaatacttg gcttacctag attattattc
    55921 tcatctgcaa tagtcactat tacagttcta tttaatatat ttactaaatt agacccacaa
    55981 aattcaataa tttgattttt attttttgct ttaagcaacg ttttgttatt ctcatagagc
    56041 aatcttatca ttttttctct cttatgagaa agtctcactt ctctttttat cctagaagtt
    56101 aaagtacttg ttataattgc tgccattagc ataatacaaa aggtcatagg ataatctttt
    56161 ctataagcta aaaaagtata taatggatgc gtaaagaaaa aattaaatga tagcactcct
    56221 attactgaag aaagtattcc aaaaaaatat ccataggtta tacttgtagc aaatagtaca
    56281 cctaatatgt atactagtat aatattagat tcattaaaac ctaccttttc aaaaactact
    56341 gatattccag tagcaattgt cataaccaat atagttttta tgaagtcctt aataattatc
    56401 tttttactga gatagccatc ttcatcataa tcatactctt ttaagtcttc atgttgtagt
    56461 cgttcctttt tcatttacta caattcctcc ttattgttac tgtttaaatt ggctctattt
    56521 tatataatac aattttatca taataaattc aatcaataca tttaattaat gtacttaaat
    56581 tactaaaagg tgctgtctta aaatgaaaat aaatctctat ttcaaaacag cacctatata
    56641 tttaaattac taatttagtt tttacatact taaatcaata gttttattca atttcataaa
    56701 ttataatact tcaattataa aacatttcta tccaacaagc ataaatataa agtgggcaca
    56761 tatacctgca cataaaccac ctatagtatg cgaaagtatc gctttaccag ccaatggtct
    56821 tgcatctaaa gcatccatca tacctatgtg tgtacttaaa tatccactcc aacacatacc
    56881 cattgctgtg aatactgcta tatcattagg agttatagcg cctgatttta taaactctgg
    56941 tactaaagat attgctgctc caacagctcc taatgcagtt acagggaatg ctattgcctc
    57001 tggtgatgtg aatccaaata atggttctat tatgaagcta atcttatcac caatagcagg
    57061 taataatttt ataccttcat atgcagctcc tgtgtaaaca gcttgacctg tagcagggtc
    57121 tgtagatggt ccaaaagtta ataacataac taatgtacaa actactaaaa ctcctggtat
    57181 tatagccata cccatttcaa cacctaactt accaccttca agtatagcat ccaatgttct
    57241 ttggaataca ttaccatccc ttatttctct aaactcttca agttttgcac ctttatcatt
    57301 tatttgcttt tcagtatcat ttttagggtc ataattataa tactttttag taaaagtcaa
    57361 cataattcta acactaataa tactacctat tattgcccca acattaccta ttatagctgg
    57421 tagtacatat tctttacctt gagctatcat aaaagttgtt acaataagtc ccataccaaa
    57481 ggctgttcct aaattacata aagcaggtac ttgatacttc ttaaaatatt gtgtaaatgt
    57541 tttgtcttta gcaaatggta taatagctgg attatcagat aaatatgttg caactactcc
    57601 tgctatacta gcaccaggta agccccatat aggtctcata agacccttaa atatcttatt
    57661 aactaaagat attactccaa actctgaaag caatgcacta agtgcacctg caagaactgc
    57721 catagccatt attaaaaata ctgtgtctaa taaaagcgca tgtgctgtac tcattattac
    57781 tttaaacatc attcctgcac ccatgatgct tcctacatat ccaaatccta ccgccaatag
    57841 tacaataaat acgaaggttt ccatacttac tgccttgact cttctcttat ccgacagctt
    57901 ttccatcttg aaatcttccc ccttttaatt ttaaattaag gttcctaaca ttggtacaaa
    57961 ttttttggta caaactgagt tctaaaactt acactcgtaa tgcaagttgt cagttttttg
    58021 aaataaaaaa aaattacgtt tatagaataa gaatatcctc tttaatttgg atactcttat
    58081 tctattttat gttattatat tatcatcctt ttgtttaaaa gtcaattttt tctatttttg
    58141 ttgtttaatt ttatttatac tctttttata tttttcattt tcttttatct ttgtaagtac
    58201 tccatataag ttgacttttc taaatacagt agttataaat accaatccta atgcaattga
    58261 acttgcacac gataatgtac tcaccccata ttctacagct tttatataat tattggtcaa
    58321 aacagaatac atagtattat atattccata accaggtact aatattatta aacagcaaac
    58381 acttaatgta gttgctggag tcatataaat tcttgcacat aactcacaat atatcgcaaa
    58441 acaaactgta gctataaaaa aacataagtt ttctgttact cccatattta aaagaaattt
    58501 atacgaaaac caagctatac ttccacctat tcctgctagt attaagtttt ttcctttcat
    58561 attaaatagc actccaaagc ttaaggcagt aaaaaaagct gctattactt ctataaacaa
    58621 atgcacttat atccccccta acttgaagta caatccaagt accaagaaca ttcctactgc
    58681 tatagataca cctacaaaaa atacttctgc taattttgca agaccagaaa tcaactgtcc
    58741 atctaacaaa tctcttaatg cattagtcaa agcaagccca ggaactaaga gcattattgc
    58801 tcctgctatt aaatggtcta acgtctttat gaatccgagc tttaaaatta aaattgaaca
    58861 agaagctata ataactgctc caattgcatt tacaaaaaag tcattaaggg aagatttact
    58921 taaatacata ataacaaact tagtcagaat cccaacagta aatgcagcta taaattcttc
    58981 cacatttcct ccaaataata tcgaaaaagt tgctgctgca atacctgcaa aaaatattgt
    59041 tattaaatcc gagtaatagt tatcttcact tatttcatct aaaattttct cacataattc
    59101 aatatctaaa ttatttatac ttattgctct tgataatgag ttaacttcat gaaccaagtt
    59161 taggtctact cttcttgagc ttattctttt aattgctgaa tgtaatttcc catctacaaa
    59221 tacagatgcc attacagctg ttggagttgc aaatacatct acgtggtcta ttccaaaaga
    59281 ttgacatatt ctagctatcg tttcttcaac tctataggtt tctcctccac tttgcaacat
    59341 agctttacct gcatttgagg aaaagtttaa aattctatct atatccacaa aacatatctc
    59401 ccattctttt atagtattat tcatatttta atacaagata ttatttattt aaactatttt
    59461 aaataattca tatccaatat ttacatttta tgaaaaaact tgttttttat gcttgtcaaa
    59521 atcaaatttt aagcttgttt acaccataaa atggctgaat taatatttga caaacacttt
    59581 caaccattta tataaccttc taaattgtat aactttttac tacaaataaa attatatctc
    59641 ttttaattct ttctcttgag tatttagctt atagcaactt catatttata tatgtacaat
    59701 ataaaacatt atttttatga tacaaaatat aatttgtaaa tgtatatatg tattaactgt
    59761 gtatatataa attattctta accttatcag ttttttcata tatcttcatc tataccgacc
    59821 atatattaat tacattgacc atatattaat aaatgatatt acatagactt aagtatatta
    59881 aaaaacttaa atttagttat ttaacaacat aatactctaa tttaatctat aaaaatccat
    59941 acctaatata atgcaactct tattttaaca ccatctatta cacaaaacaa catattaaaa
    60001 agtaaaatac aaaatatcca ctataaacct tattttaata ccgaatatat attataatat
    60061 atttaatgta gcttaaatat agtttaaaca taaagaaagg aaacggtata tgctaagaaa
    60121 agataaagtt ctattatctc tacataaatt atgtgaaaat atgactttaa aagaccttca
    60181 atcagataaa acaggattca ctacaataga aattgctaac cattcatctc ttgatagaag
    60241 taataccagt aaagaattaa ataacctata caatgaaaaa aaagttctga aaatatctgg
    60301 taagccaatt ttatttctac atgctagtat tatagaaaat ttaattggcc gtactttgaa
    60361 cagtgatgaa ttttctataa ataattgtaa tgagctactt aaatcaagta aaaatgactc
    60421 agaagatatt ttttcaacat tacttggaca tgattctagt cttaaactac ctatagaaaa
    60481 agctaaatct gctatactct atcctccaaa aggtcttaat acgttactca taggacctac
    60541 tggtgttgga aaaagtacat ttgccgaaac aatgtacaaa tatgctgtag aaagtaaaat
    60601 cttttcttct gaaagcaaat tcgtagtatt taactgtgct gaatatgcag aaaatgctaa
    60661 cttattatta agtaatttat ttggttatgt caaaggttct tttactggtg ctaataagga
    60721 taaattcggc atagttgcac aggctgatgg aggcatatta ttcttagatg aaatacacag
    60781 attaccacca gaaggtcaag agatgctttt tcttttgatg gacaaaggca tatacagacg
    60841 attaggagaa tctgacattg tgcataaagc taatgtcttt attgtgtgtg ccacaacaga
    60901 agatatacat tcttctctgc ttggaacttt tttaagaaga atccctgtta caatcaacct
    60961 acctgcttta caggataggt ctttaaaaga aagattatct cttattaaat acttctttat
    61021 tatagaatca aaatacacca atgcaactat aaaagttcac aaagatgtaa ttaaatcatt
    61081 actcctttat gattgttttg gtaatatagg tcagcttaaa tctgacatac aacttatgag
    61141 tgcaagagcc ttcttaaatt acaaaactgg acttaaggat aatatagaaa tagatttatc
    61201 ccttgttcct gattacatct atattggtct tttaaaattg aatgaaaatc gtagtaatct
    61261 aaataaatta tcagaacttg attatatgct tttttatgaa tttaatggta ataacttaga
    61321 agttgaatat acaaaagaac tatctaaata caatatagat acatcaaaca atggatttaa
    61381 atactctaca gagattcctt atctggaaaa tgatataagg agtatgttta taaattacat
    61441 ggaaaagtac tctacaaaat tactttcgat atcttcagta actcattctg attatacaag
    61501 taatgagatt tttaaagtaa tcaatccaaa gatttactat gctgttgaac attctttaaa
    61561 agaggctgaa aaaatatcga gaaacaaata cacaaaacaa acttatattg ctctttcaat
    61621 gcatataagt gcacttatag aaaatataaa tcaagacaca tataatccta agtacaattt
    61681 atataatgat aaaattttct tagataaaga tttaaatata gctaaaatag ttttaagtat
    61741 aattgaaaat gacttacaaa catctttacc taaagatgaa gtaaaattta tatccatgtt
    61801 tctaaatagc atgtatcttg aaccaaacaa tcaatctgaa agtataggag tcataatact
    61861 tgctcatgga aattcaacag caagcagtat gtgtgatgta gcaaattcat tgcttggtac
    61921 aaaccattgt aatgcaattg acatgcctct tgatgtaaaa gtaagtacca tacttgataa
    61981 aactatagag ttggtaaaag aatgtgacga aggtaagggt gtacttcttt taacagatat
    62041 gggctctctt atagcttttg gagaacttat ttcagaaaaa acaaaaatca aaactcgctc
    62101 aattgaaatg gtatctactc caatagtttt agaagcagta agaaaaagta cactaccaga
    62161 aatgactttg gatgaattag ctaattcctt aagctcttta aatccatata ttggacgagc
    62221 agcaatcgat tcaacagaaa taaactatcc tgaaaaatca agagagtatg taataataac
    62281 tacttgtata acaggatatg gttcagctat gaaagtagca gactttataa attcttcact
    62341 taaaaatatt agtaaataca atattaattt agttcctcat aatatagaaa gttttaaaat
    62401 gtataagaat aaatttagta atactaaaat tctggcagtt gttggaagtg tagattttaa
    62461 tgtagccaac acccctttta tacacataga ggaactacta aatggatatg gcctagatat
    62521 gctaaacaaa ataatagaag gtacattcaa tgccaatagt attacaaata taaaagaaac
    62581 aaatctatca tacaacagtt taataataaa ctttatgacc caaaacttag agcttttgga
    62641 ctctgttaaa ttattcaact atgtcaattc ttccttattt acaataatag aattaataga
    62701 tgaaaactta aagagcaaat ttaagctagg atatatacta cattgctctt ttatgataga
    62761 aagatgtttt aaaaatacaa cttttccata taataacatt actgaattaa ttagtaaaaa
    62821 tcatgaacta tatagtttaa tacgtgaagc ctttaagcca acagaagctt attttaatat
    62881 tttgatacca gacgaagaaa ttgcttatat aatagacatg attaatgagt atctaaataa
    62941 ataaaattta tagcacttat tttgtgcata ttaattaata tatgaaatgg aggacgagat
    63001 tttgaaagga aaaataaaac agttaacaat acttgcatta atttttatat ttataactcc
    63061 tgtatttgca tttgcagata ctccaccagt accaaattct tcaagagcag cactacttat
    63121 agaccaggaa actaaaagaa tattatttga aaaaaacatt gatgaaaaaa tgccattagc
    63181 gagtttaagt aaaatgatga cctttttatt ggcaatagaa gcagttgata aaaatcaagt
    63241 taaagagact gatatggtga aaatagacaa gtctacagct tcagtaggag gttctacttg
    63301 taaacttaaa gatggtgatg aaatatctct aggagagctt atgcagggtc taatgctagt
    63361 atctggaaat gatgctgcta tagccatagc taaacatatt ggtaaaactg aaaagaattt
    63421 tgtaaatatg atgaacaaaa aagcagaaga aataggaatg attgatacgt attattttaa
    63481 tccaaatggg cttcctatat atactgaccc agaacataaa gaacctccta ttgaaaatat
    63541 gtcaactgct cacgatatag ttacacttgg aaagtatatg tacgaccatt atgaaaatca
    63601 agttacaaga ataaccacta tgcaagtata taatgatact aaaaaggatt ttacacatta
    63661 taacacaaat cctctgcttg tttcagtacc tggtgttgat ggaataaaga caggatatac
    63721 agataatgct ggatattgcc ttgcattttc tatgatggta cctaaagatg ctaaaaacga
    63781 aagaaatcat agattgatag gtgttgtact tggtgatggt aacaagaaaa atagaatttc
    63841 ttcttccgct actttattga aatatggtaa agataatttc cattctaaaa agatagcaca
    63901 taagggtgat attatagaga ctccttgtgt tgatggtatt gatgatttta agataacagt
    63961 taaggttgat aaagatttgt atggtgttgt ttcagataac gaaaatatca atcctaaggt
    64021 agtgtttaaa aatatgaatt atcctatcca taagggagat attgttggtg ttgcaaagta
    64081 ttataatgac tctggtaaat ttgttggaag tgttgatgta aaaagtgaaa gtaatatagg
    64141 atgtattcct ttgaaggata agattaagat taaggttgct aagataaata aaaaacttga
    64201 gattaaaaat tctgtttgtt ttaaagcata gtaaagcata ttattaaaag ggtatgttaa
    64261 atttataaag actccacttt gtggagtctt tttgtttttt acaaaaaatt aaaatagtgg
    64321 caacaattga ggatgtgagg gagagttgcc actattttgt atagggtatt atattatgtt
    64381 tttaagctag ttttactatc ttctatgttt atataataac tcttgtgtgt gaatttaatt
    64441 gataattaat atgaaaatta tgtgaagttt tgatttattt gtaatatatt ctactactat
    64501 tataattttt ctactggata tactaatcat ttgtttaaca ttatctgaga ttgatttgca
    64561 aacttttata taactaaatt agttatataa cttatagatt ccattaaata ccctaataat
    64621 catatatgta catacaaagt catgcttatg caaaatctgc agtttcaact aacttattat
    64681 ataaaccatc tttatgtaga agttcagcat catttccaga ttctattact ctacctttat
    64741 ctaatacata tatattatca gcactcttaa ttgttgaaag tctatgagct attataataa
    64801 ctatcttatc ttgtatgtac tctttcaagt tgttcaatat ctctttttgt gaaatattat
    64861 ctagagctga agttgcttcg tccagaataa gtaccttttt attacttact aaagctctag
    64921 ctattgatat acgttgtttt tgacctcctg atattttgac acctttttct cctactactt
    64981 cgtccaatcc cttatctaga ttttttataa aatcatctaa acaagtaact tctaatatct
    65041 catctaattc tttatcactt attttattat ttaatactat attatttttt attgtgtcat
    65101 caaatacaaa ttgatcttga gttactatat caatattatt tcttagtgat tttaaattaa
    65161 tatcctttat attaacacca tctattaata tatcaccttc atttatatcc caaagtcggt
    65221 atattagatt tgttattgtt gatttgccac atccacttcc accaacaatt cctgttactt
    65281 cccctttctc aaattgtaaa tttatatcat ttaaaacaag gtttaaatcc tcaccatatc
    65341 taaaagatac atttttaaaa tctattttct taatttcact gttatctatt ctatatccat
    65401 tattatcaac tttaatatct atcttttcat ctattactga aaatactcta ttgatagaca
    65461 cttttgattg tgctattcta gtattcgccc ttactatagc tatacatggt ccaattaaca
    65521 ttcctgtata ttgttgaaat gctattaact cccccatcgt catcttatta tttattattt
    65581 tatatccccc aattccatat attaatattg ttatcaatcc tgttagtatt tgagatattg
    65641 ctatattact actcataatg atgttcaaat tcaaatcttt ttttatcaaa tctctctctc
    65701 tttaaatact tattaaagaa attctttttt gaatttaata taacaatatc cataatatta
    65761 gatacgtact cttgaatcaa atttgataaa ctgcctgaat cacttcttat ttcagaaatt
    65821 ttcttagata taagttttgt cattttattt tgagaaaatg ttaatatcaa ctgtaaaaat
    65881 aaaactacta aaaataaatc aaactgcaaa ttaattaaga aaattaacga tattatagct
    65941 gtaaacacat ttacaataat atcaaatata atctctgctc caaagttttc tatcataaat
    66001 atatcacttt ccataatgga taaaatatta cctgttttct tacttgaata atatctacca
    66061 gaaagttttg atatatggtt aagcaacttt acttttagat ttatagtaac tttatttttt
    66121 attgaagtat ataaatatga taatataaca tcaaatgtag ctgataatat ccttataaaa
    66181 atatatatca atattaaatt tataagcaga aaaatatttt tatttcctat cccatcatct
    66241 attatacatc taattagttg aggtattaca atatttacgc cagcaattat aaaaaccatt
    66301 ataaatgata ctatcaactt agtcttattc ttatatacta ttatatttag tattctaaat
    66361 aaattattat taatagtttt tttcatctat ttttccatct tttatagtta taattctatc
    66421 agctgtcttt gcaatattat cattatgagt tatcataact agtgtttgtt tgtactcttt
    66481 aacacaccat tcaagcatat tcataacttc atttgtagtc ttactatcta agttgccagt
    66541 aggttcatct gcaaatatta ctgacggtct attggctaaa gctctagcta ttgcaactct
    66601 ttgttgttga cctcctgata gttcattcgg atatttcttt atttgttttt caatccccaa
    66661 cttattaatt aatctcataa catattcttt atcttctttt ttcccatcaa gcaacacagg
    66721 aagtactata ttatcatata catttataac tggtattaaa ttgtaacttt gaaatatgaa
    66781 gccaaattcc tgtcttctta tttcagacag cttatcatca tttaatgtat ataaatctac
    66841 atcatctaag tacacattcc ctaaagttgg cttgtctaag cctgcaacac agtgaagtag
    66901 tgtactttta ccagaaccac ttgcacctac aatagctgta aatttatgtg gctctatatc
    66961 taaatcaata ccatcaagag ctctaacttc attctcatat tttccatata ttttttttaa
    67021 atcttttacc ttaagtattt tcataacgta tctccattcc catttaaaaa acatatattt
    67081 ttaaattaaa ttttcgtaaa taagatctac tgccatatct aaattctcta attgatataa
    67141 gtatacttct ttgtagtcaa tactaatatt aaactcttta tttaaaatag ttaaaaaatt
    67201 atatgcatta taatttccaa tacatgtaaa attgttaaat aaagaatatt cacttacaaa
    67261 ttcaaagtct atttttattt tagaaaagtt tctatttatc acatttatta ttttccttgc
    67321 tatatccaat cttatcaaat tagatttata acttggagtg ttcaagtttt ctatttttaa
    67381 atcttcttta cttttgcttt tttgaataag tatttcttcc aattcattaa acttaatata
    67441 tggattgttt tttaatatat ttgcaacaat gccagttgcc actgcacaag ccttactatt
    67501 tttaccaaaa tgagttactt tatctttaaa tttaataaaa ttatcttttg aatttgcata
    67561 catttgaatc ttattttctg gttcgtatat atattgatta tttttatata tattttcatt
    67621 acctactaca ccaataacac tttcaaatat agtaggaata ctttctttat cttcatattt
    67681 attatgtttt gaacaaataa taaatctacc ttgactattt aaaatattac aaaccttttc
    67741 taattctttt tcatacatac tattaataga tgcagctgaa atgtttatta tctgtatatc
    67801 cgacatagtc aacttgctca gtgtactaag aagatttaaa gaacttgttt ttccagaatc
    67861 attaaatata ttaataggat aaatttgggt atttttactt atatttaata tggttttcga
    67921 tacaaaagtt ccatgtccat ttatgtcatt tatttccttc ccccccaaat ctttcaattg
    67981 aaaatttgaa tcataaacat aatttccatt aatatcatca tcatttacat ctaatcctgt
    68041 gtctaagact gctattctta ctttagtcaa ttaataatca cctctaaaat aaattacctt
    68101 gaatataaaa ctaatcctta ccataatata ggttccaaga tgtttttcat ttttttacaa
    68161 tttgcatcaa acattttttt gttatttttt aaagtatata ttttcgatgg acaagttgta
    68221 caaaataaat ttactttaca ttctttacaa ctctcaatat ttactggttt taatttatca
    68281 aatatattaa atatatccat ttctctatta agaatcctct ctaatatgtt ttcattaaat
    68341 tctaatatat tgaatatctt taaatcctta tactctaagt ttggacacgg atatacatct
    68401 cctttatgat ctatacttat ctgattaaca cctgctttac acatatttga acataaacta
    68461 ctttcatcca cataatcatc tttgcaaatg taatcaatat caagtttatc attaagatat
    68521 ttgctatagt tctcattacc tctaccaata ttcataaaat ttcttattat aggcgttgta
    68581 cctaaatctt catttaattt attgaatttc tctatgtctt tctcattatt ctttcctacc
    68641 accatagaca aacctacgtt ctcgaatttt tttagtttta taagtctaat cacatttaat
    68701 actttacaga atactccttt acctcttact tcactacaac ttaattcatc ataaccatct
    68761 aaactaattt ctattgcata taaaccatta attatatcat caatctgttt ttctttaatt
    68821 aaagttgcat ttgtagacag aattatttta cctttaaatt tttcttttat ataatccaac
    68881 agctctaaga aatcatttct catcaatggc tctccacctg taatggttaa tatccttgga
    68941 tttaatttaa ctatattatc tattactttt cttacttgag atgtatctaa ataatcgtta
    69001 ttatctattt tagaatctac acagcaataa tcacaactta gattacatct attagttgga
    69061 gaaaatgaaa ttttgtttat tctctctagt ctaaattcac ttagaataga atcacttaga
    69121 agtcctatat gctctaactt atctataact cgttcataat attttttatc ttcattttct
    69181 tggaatacat catacaaatt accaagttgt aatgcattat ctactgaata ctttagaact
    69241 tcataacatt ctattggaat tttaacccat cttccattta ctttattact aagaataact
    69301 tgattattat ttattatttt ttcacatata caatctaaaa aatatttgtt tgagctattc
    69361 atttatttta tttccttcct atatatttaa attagaaatt tcattaattt tcttttatac
    69421 cacttactat actaagttta tttatcattt tattagaaaa ataaactgca atgacacaaa
    69481 caaaaacaga tatagatcca aatattagaa tttcatatat tggaatttca aatttaatag
    69541 agttatttat accatatacc tgttgattaa gtttgttagt ttcagaaact attttataat
    69601 aattgaaact agatataatt ccagctacaa tcatacttaa taccccatat atcatatttt
    69661 cttttattaa cattcttttt acattttttt tggacatccc tattgctcta aatgtacata
    69721 tctcactcaa cctcacaatt atatttgatc taactataaa aataatgttt atagatgata
    69781 ttaataaaac tccaaataca caaatcattg ctaatttata tgaggattta ttataatggt
    69841 ctccaaaatg attacgtaca tatcttccct ctatatctga aaatccactt ttttctatta
    69901 tattatttat ttcttttatt acttttttat ctgtttcttt ttttatc
//
LOCUS       DAGQVA010000010        69202 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.010, whole genome shotgun sequence.
ACCESSION   DAGQVA010000010 DAGQVA010000000
VERSION     DAGQVA010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69202
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.010"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            64..873
                     /locus_tag="MIV85_000788"
     CDS             64..873
                     /locus_tag="MIV85_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2960157.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKIYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            1007..1246
                     /locus_tag="MIV85_000789"
     CDS             1007..1246
                     /locus_tag="MIV85_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960158.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1434..1610)
                     /locus_tag="MIV85_000790"
     CDS             complement(1434..1610)
                     /locus_tag="MIV85_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960159.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1664..1760)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2115..2789)
                     /locus_tag="MIV85_000791"
     CDS             complement(2115..2789)
                     /locus_tag="MIV85_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBY2960160.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3009..3563)
                     /locus_tag="MIV85_000792"
     CDS             complement(3009..3563)
                     /locus_tag="MIV85_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBY2960161.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIITKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3641..4006)
                     /locus_tag="MIV85_000793"
     CDS             complement(3641..4006)
                     /locus_tag="MIV85_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960162.1"
                     /translation="MKIRAEYTCLLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4471..5256
                     /locus_tag="MIV85_000794"
     CDS             4471..5256
                     /locus_tag="MIV85_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2960163.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5353..6177)
                     /gene="pdaA"
                     /locus_tag="MIV85_000795"
     CDS             complement(5353..6177)
                     /gene="pdaA"
                     /locus_tag="MIV85_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBY2960164.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6398..9517
                     /locus_tag="MIV85_000796"
     CDS             6398..9517
                     /locus_tag="MIV85_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBY2960165.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPVEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FLEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKYRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9535..10134
                     /locus_tag="MIV85_000797"
     CDS             9535..10134
                     /locus_tag="MIV85_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBY2960166.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10391..12520)
                     /locus_tag="MIV85_000798"
     CDS             complement(10391..12520)
                     /locus_tag="MIV85_000798"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBY2960167.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12786..13034
                     /locus_tag="MIV85_000799"
     CDS             12786..13034
                     /locus_tag="MIV85_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960168.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13200..14591
                     /locus_tag="MIV85_000800"
     CDS             13200..14591
                     /locus_tag="MIV85_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBY2960169.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14706..16175
                     /locus_tag="MIV85_000801"
     CDS             14706..16175
                     /locus_tag="MIV85_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBY2960170.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16240..16833
                     /locus_tag="MIV85_000802"
     CDS             16240..16833
                     /locus_tag="MIV85_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBY2960171.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            17015..18361
                     /locus_tag="MIV85_000803"
     CDS             17015..18361
                     /locus_tag="MIV85_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBY2960172.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            18543..18914
                     /locus_tag="MIV85_000804"
     CDS             18543..18914
                     /locus_tag="MIV85_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBY2960173.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18907..19596
                     /locus_tag="MIV85_000805"
     CDS             18907..19596
                     /locus_tag="MIV85_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBY2960174.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20116..20982
                     /locus_tag="MIV85_000806"
     CDS             20116..20982
                     /locus_tag="MIV85_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBY2960175.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21224..22033
                     /locus_tag="MIV85_000807"
     CDS             21224..22033
                     /locus_tag="MIV85_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960176.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22177..23241
                     /locus_tag="MIV85_000808"
     CDS             22177..23241
                     /locus_tag="MIV85_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBY2960177.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23269..23988
                     /locus_tag="MIV85_000809"
     CDS             23269..23988
                     /locus_tag="MIV85_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBY2960178.1"
                     /translation="MTSWKKKTVYKCLIAVALFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            24012..24596
                     /locus_tag="MIV85_000810"
     CDS             24012..24596
                     /locus_tag="MIV85_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBY2960179.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24598..25947
                     /gene="pabB"
                     /locus_tag="MIV85_000811"
     CDS             24598..25947
                     /gene="pabB"
                     /locus_tag="MIV85_000811"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBY2960180.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25937..26680
                     /locus_tag="MIV85_000812"
     CDS             25937..26680
                     /locus_tag="MIV85_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBY2960181.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26714..27415
                     /locus_tag="MIV85_000813"
     CDS             26714..27415
                     /locus_tag="MIV85_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960182.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKILNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27441..28013
                     /gene="folE"
                     /locus_tag="MIV85_000814"
     CDS             27441..28013
                     /gene="folE"
                     /locus_tag="MIV85_000814"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBY2960183.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            28077..28868
                     /gene="folP"
                     /locus_tag="MIV85_000815"
     CDS             28077..28868
                     /gene="folP"
                     /locus_tag="MIV85_000815"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBY2960184.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28879..29244
                     /gene="folB"
                     /locus_tag="MIV85_000816"
     CDS             28879..29244
                     /gene="folB"
                     /locus_tag="MIV85_000816"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBY2960185.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            29237..29743
                     /gene="folK"
                     /locus_tag="MIV85_000817"
     CDS             29237..29743
                     /gene="folK"
                     /locus_tag="MIV85_000817"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBY2960186.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29724..30509
                     /gene="aroF"
                     /locus_tag="MIV85_000818"
     CDS             29724..30509
                     /gene="aroF"
                     /locus_tag="MIV85_000818"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBY2960187.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30764..32554
                     /locus_tag="MIV85_000819"
     CDS             30764..32554
                     /locus_tag="MIV85_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBY2960188.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32572..33738
                     /gene="rpoD"
                     /locus_tag="MIV85_000820"
     CDS             32572..33738
                     /gene="rpoD"
                     /locus_tag="MIV85_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBY2960189.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33903..34592
                     /locus_tag="MIV85_000821"
     CDS             33903..34592
                     /locus_tag="MIV85_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBY2960190.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34606..35703
                     /locus_tag="MIV85_000822"
     CDS             34606..35703
                     /locus_tag="MIV85_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBY2960191.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35766..36338
                     /locus_tag="MIV85_000823"
     CDS             35766..36338
                     /locus_tag="MIV85_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBY2960192.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGTPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(36398..36865)
                     /locus_tag="MIV85_000824"
     CDS             complement(36398..36865)
                     /locus_tag="MIV85_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBY2960193.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37251..37727)
                     /locus_tag="MIV85_000825"
     CDS             complement(37251..37727)
                     /locus_tag="MIV85_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBY2960194.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37847..38938)
                     /locus_tag="MIV85_000826"
     CDS             complement(37847..38938)
                     /locus_tag="MIV85_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBY2960195.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38931..39320)
                     /locus_tag="MIV85_000827"
     CDS             complement(38931..39320)
                     /locus_tag="MIV85_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2960196.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39512..39958
                     /locus_tag="MIV85_000828"
     CDS             39512..39958
                     /locus_tag="MIV85_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960197.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40222..40947
                     /locus_tag="MIV85_000829"
     CDS             40222..40947
                     /locus_tag="MIV85_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960198.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            40934..42178
                     /locus_tag="MIV85_000830"
     CDS             40934..42178
                     /locus_tag="MIV85_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960199.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGQGTEFHIIFHKMYDSD"
     gene            42258..42935
                     /locus_tag="MIV85_000831"
     CDS             42258..42935
                     /locus_tag="MIV85_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960200.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42936..45497
                     /locus_tag="MIV85_000832"
     CDS             42936..45497
                     /locus_tag="MIV85_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960201.1"
                     /translation="MNLYTLLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINNSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIITIVSIIIVLLTIF
                     ISILLPAISASNISHLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            45718..46992
                     /locus_tag="MIV85_000833"
     CDS             45718..46992
                     /locus_tag="MIV85_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBY2960202.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(47153..50194)
                     /locus_tag="MIV85_000834"
     CDS             complement(47153..50194)
                     /locus_tag="MIV85_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBY2960203.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            50401..50700
                     /locus_tag="MIV85_000835"
     CDS             50401..50700
                     /locus_tag="MIV85_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBY2960204.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(50938..53166)
                     /locus_tag="MIV85_000836"
     CDS             complement(50938..53166)
                     /locus_tag="MIV85_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBY2960205.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            53459..55234
                     /locus_tag="MIV85_000837"
     CDS             53459..55234
                     /locus_tag="MIV85_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960206.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
     gene            55247..57070
                     /locus_tag="MIV85_000838"
     CDS             55247..57070
                     /locus_tag="MIV85_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960207.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            57188..57733
                     /locus_tag="MIV85_000839"
     CDS             57188..57733
                     /locus_tag="MIV85_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBY2960208.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            57993..58601
                     /locus_tag="MIV85_000840"
     CDS             57993..58601
                     /locus_tag="MIV85_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBY2960209.1"
                     /translation="MVDNLIKYIHKSYVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            58928..61825
                     /locus_tag="MIV85_000841"
     CDS             58928..61825
                     /locus_tag="MIV85_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2960210.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLNSGYEYSVLYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNIAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKYKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSNLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKANMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSIESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLKKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            62146..62358
                     /locus_tag="MIV85_000842"
     CDS             62146..62358
                     /locus_tag="MIV85_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBY2960211.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            62371..62592
                     /locus_tag="MIV85_000843"
     CDS             62371..62592
                     /locus_tag="MIV85_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBY2960212.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            62692..64848
                     /gene="feoB"
                     /locus_tag="MIV85_000844"
     CDS             62692..64848
                     /gene="feoB"
                     /locus_tag="MIV85_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBY2960213.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            64874..65026
                     /locus_tag="MIV85_000845"
     CDS             64874..65026
                     /locus_tag="MIV85_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBY2960214.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            65206..65916
                     /locus_tag="MIV85_000846"
     CDS             65206..65916
                     /locus_tag="MIV85_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBY2960215.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            66001..66771
                     /locus_tag="MIV85_000847"
     CDS             66001..66771
                     /locus_tag="MIV85_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960216.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            66764..67495
                     /locus_tag="MIV85_000848"
     CDS             66764..67495
                     /locus_tag="MIV85_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960217.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            67529..68488
                     /locus_tag="MIV85_000849"
     CDS             67529..68488
                     /locus_tag="MIV85_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2960218.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(68586..69182)
                     /locus_tag="MIV85_000850"
     CDS             complement(68586..69182)
                     /locus_tag="MIV85_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBY2960219.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
BASE COUNT        27424 a         7308 c        11569 g        22901 t
ORIGIN      
        1 tattatagag taataatgtt gatttaaaat aaaaataaga tttcggagga gtttattata
       61 taaatgaaag attactataa aataggagag atatctaaaa tatatggaat aggtagagat
      121 tcattaatgt attatgaaga aataggcatt ctaagaccag ttagagatat aaatggatat
      181 agaatgtata atatatcaga tatatggaaa ttaaatttaa taaaagaatt tagaagcttg
      241 aactttccaa tgaagaaaat aaaagaatac ctagatgaca gaagtataga gtctacgaaa
      301 aatattttaa atgaagaact cgatttaatt gataaaaaaa tagctgaatt tataagccat
      361 aaggaaaata ttataaaaag attgagttca attgaaagtg taattcaaaa tacaaaaata
      421 gatgagatag aggttgtata tatagaaaaa agaaaagctt tagaattaaa tgctgatata
      481 aagagggatg aagacttcga ttttttaatt caaaaacttc agaaagaata tgaagataga
      541 tttaatatac ttggaaacaa caatattggt tctgcctttt ctactgaagc aattaataaa
      601 ggtatattta atgagtttaa atctgtattt tgttttctgg aaagtaatga gaaagtatat
      661 aatatagttt ttgatgaagg atattatgta actttaaatt atactgggag taattctaat
      721 aataagatat atatggagaa ggtgtttaaa tttatagaag aaaataatta taagataatt
      781 gctgacccta tagaaatcta taagatagat atacatgaga ctggaattgt agaggagttt
      841 gtaacggaaa ttcaagttcc tataactaaa tagctatatt tcaatggatt agatggtaaa
      901 tagaatgaaa aaatgttgat ttgccactgt gttataaaat cggtagcaaa ttatatttta
      961 aattataaga tagcatgaaa aaataattgt ttagggggtt ataaatgtga aatgttctaa
     1021 ttgtggaagt gtaaatattg aaaagggaat tttaacaact ggtggcatat atgctgaaac
     1081 tattggatta aaatatagag gagatggaaa attagataaa gttataaata aaacttttcc
     1141 agtacaatct actatatatt cagatttatg tttagattgt ggagaaatag ttagaaccta
     1201 tataaaggat aatactgata ggaattggtg taaagataag aaatagaata atttttgaag
     1261 tatattaata tttgaagttg aattttatta aagatacaag tgaaaaagta taaatgggaa
     1321 gaaattgtta tatggaagaa aactttgcat ataggggaga ttagtttttt aatataataa
     1381 catttttaaa tgtagataaa actaaaaagg gttctctaga aaacaatttc tatttaatta
     1441 tacttactta ccaataccat cacttgatgt aaacaagatt ctactacatt ttctccgtac
     1501 tctagtataa aatcatctag ctgtgtatct ataaaatcac aataatcata taaactactg
     1561 atataagcag ttaacatgtg tgtacattta tccatttcat ctctaaacat atatattact
     1621 atccccctaa aaaactttca taaaacaaaa agaacaatat ctttttggca actggctgac
     1681 ataactcata gtttatttta taagcgttag tccctatagc tttgcgtcac taaatttctc
     1741 tagttttgcc gatttagttt tattctacaa ctaaaataat acactaggat aagttattgt
     1801 tcaacatact tgtcagaaaa ttgaaatatt taacagtatc ttaacaatat gaaatctatt
     1861 tttcactcaa gaaataaact atacatgtag aatatttaat aaaaattata tttagttttg
     1921 tattgaagtt tttgtattaa aaagtttagt tcacaagagt tacttggcta gataatagat
     1981 gaacaaaaat atcttgaaaa aatatatatg aatggcaaaa aacaagggat gaattttata
     2041 tagactcatc ccgtaattat ttatatattg accttgatta aatatattat tatttttaag
     2101 cttcaatttt tatattatat ttctaaagtt tctataagag gattatcgct aaataatttt
     2161 aataaatttg tttttttata tcctttaggt aacttagtat atataactac ttctaaccaa
     2221 tccccatcaa ggcgtttaat attcatgttt ataatttcaa tattagattt tttaaattta
     2281 ccttcaatat attctatgga atcagtgctg ttagaaattt taagagaaac ttgctctgct
     2341 gtagggagtt tcatccattt cctatctcta tgaagtgtta tctgtacaat aacaataatg
     2401 atacttgaaa caataccaac taagtataat ccagagccaa tggcaagacc tgtaccagct
     2461 gttgcccata taccagcagc tgtagtaaga ccacttactg attgatttct aataaatatt
     2521 aatccagcac ctaaaaaacc tataccactg acaacttgtg ctgcaacgcg ggctgggtct
     2581 agaccaatac ctggagtacc cactatatca ttaaatccat acttggaaac aatgattata
     2641 agtgctgaag ctaatgccac tataaaatga gtgcgtattc cagcttcttt tagtctattc
     2701 tttctctcat atccaattaa agccccacag aaaccagcag taatgattct tgctatatat
     2761 tcaaattgaa tcaatatatg atggttcatt tatctagcac ccccttctat ataatattat
     2821 atatactata atactacatt ttttatgtga atatagtaaa gtttaaaatt tatataatag
     2881 ttatatatga atataaaatg tataaacgta tattatgtat ataaaaatga tagaaagcat
     2941 ctaattttaa atgattaaag agcaagctta aataaatcaa acttgctctt ttaacatagt
     3001 gtatgttttt atttgtgata gttagataaa aatttatctg tgttttttac atctgcaaaa
     3061 ctgttctgta gtgatgccat gaatacttga tgtacagtat ttgcattaat ttctatatta
     3121 ttccaagata aattcttcgt tgtacatgca tcgcttatta gagttatgtc gtatcgaagt
     3181 ttctttgctg ttcttacact tgtatcaata cacatatggc tcatcattcc acagattact
     3241 agattagtaa tatttttttt ctcaaggata ctttgcaaat ctgtttcaaa gaaactatct
     3301 ggtgtgtgtt tagttataat ttcttcatta tctagtggaa aaacaatttt atttatttct
     3361 gaaccatgag tattaggaag aaaaaaagaa gctgttttat ctgttgatat atgctgtata
     3421 tgaataactg gtaaattgtt ttttctaaaa aacagtagta tttttttagc attttcagca
     3481 gtttcttctg attgaaataa ttcacatttt ccatttttaa aataatcatt ttgaatatca
     3541 atcaatatta aagctataga catgattata cctcctattt atttttatta taatactatt
     3601 gtaaaaaatg taaattactt actttttggt atgtatagga ttacttattg tagcaaattc
     3661 ctttattatc tagaatttct tgttgaccat gttcaagcat atattcgatt cctatttctt
     3721 gcattatttc cactgctttt aacatttttt taccacgatt agtaagaaaa tattcaacat
     3781 gtaatggata tccagcagaa cttattttat caataatccc aaaatcacgt aactctttta
     3841 attgttgaat caacattttt tgatttattc cataaatatt atgttgcaat tcagaaaatg
     3901 ttttattaga ttgtcttaat tcaaatataa ggatagtttt ccattttcct ttgattatgt
     3961 catgtacaat ttcaagaaga catgtatatt cagctcttat tttcatagca tatcaccccc
     4021 agtaaaatga taataaatta tatcacttgt cttgtgatat gacaaatata tatgaactgt
     4081 atataaattt tatgttttat taagttctaa atttcttcta ttgtagttca tatttagtac
     4141 ataaataatt agtaagatat aagtaaataa atatataaca tgactataga aatttaactt
     4201 taaaataact tatgataatt tagaggagga atatatatga atatatcaag aaaagctatg
     4261 aaaataatag aattagcaca aaaaattgca aataagagag gtatttcagt agaagaagct
     4321 tggagtgaag cagtaacaga atataaaaat aaatacgaac atattgcata gatatttaaa
     4381 aatttagaat atttggtaga atataatgat tttaaatgat actataaatt ataaggtata
     4441 tcattattaa catagaagga ggatatctgc ttgattgtaa aaatagataa tactttagaa
     4501 aaagaatttt ggcaatatgt atcacatgaa gaaagtttaa atttattcat aattggatac
     4561 gttgagaatt atggatttag ctctcaatat caagatatat ggtctcaggt agaagatgga
     4621 aatataacct ctataatatt aaaaaataag tcaacactta taatttatag ttttaaaaat
     4681 aattttaata taggagaaat gaagaatcat ataaaagatt tagatgtaga aagcataagt
     4741 ggaaaaaaat gtgtaataga tagactaata agtaaataca aagattttta tgaaaaacta
     4801 gataataaat tttgtgtatt aaaagaaata aaagaaatag atttttccaa catgaaggag
     4861 tataaaatag aaaatgctca ggaaaaagat attgatgaaa taggaaaact tttaaatagg
     4921 tcagactata aagtaagtaa aaattacata gaagaaagaa aagttcattt aaaagaggga
     4981 aatgtaagag catattttat tagaaatgat gatactatga ttagcactgt gtcaactggt
     5041 atggaaacta gttttttggc aatggtggtc tctgtaagta cagataaaag atatagggga
     5101 aaaggacttg caagttatat ggtttacaat ttgagtaaag aattgttgtt agaaggaaaa
     5161 gttccatgtc ttttttataa taatgatgta gcaggtaaaa tatatcataa tataggatac
     5221 aaagagataa atgaatggac aattcttttt aaatagctat aaaaaataaa aaactctatc
     5281 gagaattaaa gtatttataa ataactatat ttttactata attcatgata gagttttttt
     5341 aaatttatga tactattttt tattatttaa ataatcaagt gttttaagtt tataaccttc
     5401 tttttcccaa tgtgtaagaa cctcatctaa tatctcagta tttgttgatg aatttggatg
     5461 cagtaaaact attgcaccag gatgagttct tgaataaatt ttgtttttgg caaattcatg
     5521 agtaggttgt ttcttttcat accaatctac ataagcaaaa ctccaaaata ttgatttata
     5581 tcctaaatct tgtgtatatt ttaaagattg ttcgctaaat ttacccattg gaggtctaaa
     5641 atacttaggc atttcttttc cagtaacatc tttgtatgct ttttctacac ttgtaatttc
     5701 ttctttgaat ttttcaaaat ctgtaatacc tgccattgat ggatggcttt ttgaatgatt
     5761 acaaactaaa tgtccttctt tttccatacg ctttattaac tctggattgc tttttatata
     5821 actttcaact acgaaaaatt gagctttagc attgtgtttt ttaagcgtat ctaataattt
     5881 tggagtgttt ccactttcat atccagcatc aaatgataga tatataactt tttcattggg
     5941 atttcctaca taataagctc cgtatttttt aaaaaaatca gcttctttta taggtgatgg
     6001 ctgtttacca tcctccctag ggttaaaata ccaatcatat tcatgtgtgt cgagtgttgg
     6061 actagaaatt tgagtttttg ttttatctaa tgatttaaaa tttatactag caattccaaa
     6121 aagtattaga gcaaatgctc ctatcataat gtattttttt aggctatctt ttttcacaat
     6181 ttcacctctt atttaaaatt taaagtatat ttcttataat atagtttgaa tatttatagt
     6241 taaaaatatt cacatataca aataataaat gaaagaagtt tactgtaaga tataaagttg
     6301 atattaatta tcttaaataa agtgtatata aatgataaaa tataaagaga aatgattgta
     6361 aataagttag gctggtttaa cttgaaggga tataaaaatg gataatataa taagtgtatt
     6421 gaatgatgtt gtttttttag atatagaagt tagtggatta gattgtttaa attcagaaat
     6481 tttagaagtt ggagctgtca aggttaaaga ctggaaaata tatacctatg aatcattaat
     6541 aaaaaacaaa tttgaggtac ctgtagaagt attctcagta tgtaaaaatt tagataaaaa
     6601 tgatttagaa atagctaatg aaatagaact ggtggaagat agacttgtaa attttgtaga
     6661 agatagtttc attatatgtc atgatttaag tctgaaaaaa aagtttcttg agtatcatat
     6721 gccaaagtta aaaaacaaat ttattgattt aattgaatta gcagttattt tagaaccata
     6781 tcataaagat tatagcttag aatacttaaa aaatacttta acaaattgta attctaaagt
     6841 ggaaaataga gctttatcag atgctattga tataataaat attgtaaatt gccttttagt
     6901 aaaatttaat aactatgaaa aaactacttt ggagccattg agttttaaaa taaattcata
     6961 tcttaaaaaa tttaatcttc caacatggga atggagcaaa tttttagaag aggcaaatta
     7021 tgatttatca aataatataa atataaaaaa agaatataat atatttgact caaaagaaga
     7081 aaagaagaag gaaagagaaa ccttaaaaat tttaaatgaa gaagaaaaaa attatgaaga
     7141 attattaaaa tacaaaacta tttgggagaa taaagaagga tttacatatg aatatagacc
     7201 tggtcaatat gagcttacta aaacaataag agagttgttt agaaatagcg aagatgaaga
     7261 aaaaattgca tgtatagagg caccaactgg tataggtaaa agtgtaggat atttattgcc
     7321 tgcaatatta gaggctagaa ttaataaaaa aagattatta atttctactg acacaaagga
     7381 attgcagata caattaataa ataaagatat tccaaatgtg ttagattctt tgggtctaaa
     7441 tggaaaagta agttacggat atataaaggg aaaaaataac tatatttgta tagatagact
     7501 ggaagcatat atagatgatt atgagtctca aaaccctact aaaggagaaa ttttatcttt
     7561 aatatttttg aagagattag ttgaaggtgg caagtatgga gatatagaag aaataaatta
     7621 tttagtgttt gacaacttca aggaaataag tactcactta agaaatgtaa gttgtgaccc
     7681 aaatatgtgc agacctaaaa aatgcaaaaa agattgttta tataaaaaca gaatagaaga
     7741 attaaaagaa gaacatataa cagtagtaaa tcattcacta ttagctaaat ggccatataa
     7801 ggatgaaaaa cctttagaaa atataatagt agatgaagca cataatttga ctgaaaaagg
     7861 atatgatttc ttttcaagca ttataaattc aaagtcttta aggtatttat tacaagaaat
     7921 ttatccttac gagtttattc aaaatagtag ctttatatat aaaaaatata gtagaaatat
     7981 gagaaaaata aaggcttttg ataaatttta taatgtatta aaaattggaa gagaagataa
     8041 acaaaaaatt gctagaagta taaatctcat tattgaagag atagattcaa tattaaagtt
     8101 tggtaattgt aatgaatata ataatgtaag taattataat ttaagatggg aactgaattt
     8161 gcaaatagac gaaattgtgg gaaaactaaa aaaggatggt atagatactg aaataagtta
     8221 tagagcctat agtgaaaaga taaagttgag ttgtgagaaa ataataaaaa atttagtttc
     8281 aataataata ataatttata ggaatattga tgatgatagt atagataaag aagcagatat
     8341 atataaattt ggaaaggcaa agacaagaga tttagaggat ataaagatta tatttgaaat
     8401 ctttttagag tatgatgaaa aggatgatta tgcaaggata gttgaaattg ataagaatta
     8461 taatgacttt gaatttcgag tagtgccatt aaaaatagca gatttatttg aagaaaatat
     8521 tttatctcaa ttagaaaaag gaatattttt atcagcaact ttgagtttat ctgaaagtat
     8581 gtcttatttt aaaaatacat taggaataga cagagttaag aatgtggaaa agattataga
     8641 accaattttt gattataaaa atagagtctc tgtagttgga ttttctgata tttgtgagta
     8701 cagaaattct gaatttccaa atgagatgag taaaattata tctaatatat caaagattac
     8761 agaaggtcat acattagctc tttttaatag taaagataga caagaaaaaa cttatgaaat
     8821 attgaaaaaa tacttacata gttttaactt agaaatttat gctgataaaa aggggattag
     8881 acaccttaac gatttaaata gaaaatgtgt agtacttggc tcaaaaggat gttttgaagg
     8941 cgtagacatt ccaggggatg gtttggtttg tgtaacttta gacaagcttc cgaatctaaa
     9001 tccaaaagac cctttgtatt ttactataat gaagaagtat ggtatagact actatactat
     9061 aaattatcct caaatgacca taaaggtaaa gcaagctatg gggagaattt taagaagcaa
     9121 atatgactat ggatgttttg tgatttttga tgtaggaact aatataagtg tgttaaagag
     9181 attagagaaa gatttacacg attgtaaaat ttcaaaggtt aatagcaatg agttttatac
     9241 ttatataagg cgacatttaa ataaatatag aagtttaata ctaaaatctg ttatatttga
     9301 tactataaaa gcgttgaatg ttgatgctaa aatggataac aatgatgttg ataaggatat
     9361 tataaaaaaa gatataaatg aaaatataag acaaagagct gtaaaaggag aagtgtacca
     9421 tattgatatt ataaaaaaag atatgaaagt aaaatatttt gatagaaact atcttataaa
     9481 tttagatata tttatgagag aagaagataa aaattaagag tgggagtgat atatttggca
     9541 aaacaaaagt tttatgctgt gaaaaaaggt aaaaatatag gtgtatataa tacatgggat
     9601 gagtgcaaaa aacaagtaaa tggattctca ggagctgaat ataagagttt ttctactttt
     9661 caagaagcta aagaatatat tgatgggtca gaaaaattga gttttcaaga agataaggag
     9721 tttatagaag catatgtaga tggaagttat gaacattcag taaaaatgta tggttcgggt
     9781 gttgtgattt taaaaaataa tgaagttata aaaacttata gtgaaaaagg aaaagagaaa
     9841 actttagtaa gtatgagaaa tgtagctgga gagatagagg cttctaaaat tgcaatgcag
     9901 tactgtattg acaataatgt tcaaaacttg attttatact ttgactatga agggattgaa
     9961 aagtggtgta ctggagtttg gaaaacaaat aaagaaggaa ctatagcata taaaaatttc
    10021 tatgacagta ttaagaataa gcttaatgta aaatttacaa aggttaaagc tcattctgga
    10081 aataagtata atgaggaagc agataaatta gctaaaaaag ctattggtgt ataataaaaa
    10141 aatatttata cataattaca tggtataaga gtatatctaa attcctactt tataattaaa
    10201 caacttgtaa ttaaacaact tgtaattaaa caacttataa ttaaataaat tttgattaaa
    10261 aaagcagatt gtattatgaa aaaataagta tctaatttat aaacaattaa taatagtatt
    10321 aattagatac aacttattta atataataaa atctgctttt tatataacta taaaattttc
    10381 ctacattcta ttagaattgc ccataaatac cttcaagttc ttcttttaat acttcagggt
    10441 catttatacc aatagacatg gttctagcca gtatatttgc ttggtcataa gttgatgtcc
    10501 atgagaatac accacctaga caatttctaa gaacatattg agtttttaag aatattgata
    10561 aagcatcatc atatgacatt gcaaaatctc catccttaac taaatatgga acttgagcag
    10621 tattatcaaa tctatattca tatccatttt tatttatata atcccttcta agctcatcat
    10681 aagttcttgt tatagtagca cctaatcttc cataaaatgg tataccaaga aggatttttt
    10741 cagaaggcat tccagcattc tcaagatttc ttaccattgc atcaacacta tatcctggca
    10801 aagataagtc tgaatcaaaa agatttgctt gatgttttct accatttggg cctgtttcac
    10861 ctgctgtaaa atcataactc ataagattaa aataatctat tataggagct attttatcta
    10921 tttcagcact tgaatttata tatcctctat ctcctgttcc agctacacta agccatttat
    10981 catctcctat aacatctctt atggcagtta gtaagagtgt aaagttttct ctatcttgag
    11041 gtcttgatgt tattccagat gcactacttc caggatattc ccagtctata tctattccat
    11101 ctaaagcata ttcatttatc atctgattga cctgtcttgc aaaattatat ctagatgtag
    11161 gtgttaatgc tgcatcagag aatccttcag ctccccaacc tccaatagct acaattactt
    11221 ttaagctagg tttttcacct ttaagagcaa gtaattgatt taaaaatcta ggataaggaa
    11281 taaacaaatt tccagactgg tctatctcag caaaagcaaa tataactgca tctaatagtt
    11341 gagcatctac attagttgga tttccaagaa catattctgc tacaattgga tttatatctg
    11401 gacagtttgc attttcaact attggattgt atgggtctgt tatttgtggt ctaactaatt
    11461 ttttagaatc ttttaaagtt ttcatagcta tttttttagt atttttttcg ctagtataat
    11521 cgtagttttt ataattatgt ttatagaaat cttcataact actatcttct ttgttatagc
    11581 tagaatttat tttgtcacaa gattcatctt tatcatagtt aaaattcatt tcatcacaag
    11641 acttatcttt aaacttatct tgtttggagt tgtgaacttt gttagtattt ttagtatgtt
    11701 ttttctcatg attgcaatca tctttaatat cagtcttgtg ttcttgttta cagtcaagag
    11761 ctttgttcag gtagtcatga tgttcatgtt cacagttaca ttcattttca atgtttttag
    11821 tatgttcttt tttccagcta caagtattat caattttctt gctcacttct tcatcattat
    11881 aattatctgg tacaaaacat aagtaccagt ccatacatga atatttctta ttacaactgt
    11941 taactctatt ttttaattcc ttatagtttt taggataagg taaaatcact ggcattccag
    12001 gaaaccagtt tgcaggagta actatattat ctctatcact agtctgaagt gcatctacta
    12061 ttctaagtat ttctggaata tttcttcctg tagttagtgg ataataaaga atcgttctta
    12121 gaatttgatt attatctata ataaatacag agcgaacagt tgatgtatca ctcattggtt
    12181 ttgatatcat gccgtataac ttggcaattc tcatatctct atcttctata ataggaaatg
    12241 gaatttctac acctgtaagt aaagaaatat tatacatcca agctaaatgt gaactgttac
    12301 tatcaacact tagaccaatt agttctgtat ttcttttttt aaattcgtca taatatttag
    12361 caaaacataa aaattctgta gtacaaactg gtgtaaaatc accaggatgt gaaaataaaa
    12421 caatccaatt acccttatag tcagagagtc taataggacc atttgttgta ttggctttaa
    12481 aatcaggagc ctttgaccct aaacttggca aatttggcat gtaaatcacc cctcaataaa
    12541 ttatcattta ttttattcta ttaattaata catattagtg ttactatttt attaaaagtt
    12601 aagtaatcct tatgtcaaaa aaagatattt attaaaaaga tttaatattt tcctaatata
    12661 aatgacaata gtaattgcta tttttttact aatttggtat agtaatggat aaggggtagt
    12721 gtcaatttta gtgattatac gaggtgagtg gattgaaaaa aattctaaga attttagtta
    12781 tctccatgat gatatgtttt gcaatgactt ttgcattagt gttaataaat tcagttatgg
    12841 gagtacatat aggattggat tattactttt tgatgggaag tgtgcttaca gtttgtttaa
    12901 caattggaat tgttttatgc aatgctagaa aaatatttga tagcaaagct atacacaaga
    12961 caagaacgaa aactgtcagt aataataaaa aacaaaagag tcattctagg gatataaaaa
    13021 gaaagatatc ataatttatg taaaggaaat atttatgtat aaaataatga ttgataggta
    13081 aaataaaaac acgatttaac ttgtgttttt attttttttc aagaattatg atataataac
    13141 caataagaaa tttagtttac cataaaatat aaagattatt aaatggagag ggaactataa
    13201 tgaattttag agatttattt gagaaggctg tagattttat tgatgaaaaa aggaaatcta
    13261 tagttgcgat ttcattatca acattaggtg taattgcttt gataatagta tttttcttaa
    13321 gtagtaacga gtttagtgta ggaaatgaag ctaatgagtt gttaaagatt atagagaaaa
    13381 gacagtattc tatagctgtt gattactaca caagtataga aaaaaagttt tctgattcaa
    13441 aaatggaaag gtttaataag tctgtttcta aaaaaataaa taaattgcta ttaaatagtg
    13501 gtgataaata tttagatgga gacataagtc aagaaagttt tattggatta ataaataccg
    13561 tgaaagaatt aaacaaaata agtatagatg tggatgactt attagctcaa gctgatagag
    13621 ttagagaaat gtataaagaa gaaaatacta cttatgatat tgccattaac tacataagta
    13681 ctgtttcaat attaaatggt atgggtagta acctagatgt atacaaacag aatatagaaa
    13741 caatcaaaga gtctagagat gtttatgact cagcagtaaa agaccaaaaa gcatataagt
    13801 attatgaagc tattgaaaag tataataaag tattaaaaga agatgaaaag tattacagta
    13861 tggctcaaaa tgggaaagaa caatgtattg aagaaatgta tgattactat ataagtagag
    13921 ctgaagaggc aaatacttct ggagattatg aaagagcatt acaatatatt gagtatttaa
    13981 aagacgatta ttcagatgat gaaaaggtac agagtttaga aaaaaaatat aaaaagaatt
    14041 tatcattgta tactttaaca tctgatgaca ttataaatgt aatagctaaa aaaagtggca
    14101 aagacaaggc aaatctatct ataaattcac ttccacaaat gataaaaaat aataaatact
    14161 attatgctga agtatatgag tatgataaat taataaatga agttttggta agtgcaaaaa
    14221 ctaaagattt atattcatat aaagatggta aaaaagatta caaagtagat tatggtgatg
    14281 gatactttag aatattagaa gatggaagtt atcaatttgg tattacaaaa gataaagcta
    14341 agtttgtgtt aactaatact cttgatgaaa aagaaaataa gtataaaaag attgagatat
    14401 tagatataga gaaagcagat agatatgtaa aaagtaaaaa gagtttagaa gaattgtttg
    14461 gaaaatataa aaatatttat tattatgctg tagtaaataa aggcttattt agaggcaaag
    14521 aagtttatgc tattaatatt tacaatgaaa aaatatatgc catatcagaa aatggactaa
    14581 atgaatatta attaataata ttaaattaat atataattaa aaagtttttg gggttttaag
    14641 gcgcattatg tagtaatata ataataggga tatataaata attttattgt aaggagaagt
    14701 atgggatgag taatgtgaac aaaaagctag ttatagctat tggagctgta gcattagtag
    14761 taataatttt tataggcata atgtgcatgc aatttaaagg ggagaaaata gcaaaaaaca
    14821 catatgttaa tggagtaaat attggaaaat taactaaatc acaagcaaaa caggaattag
    14881 ctaaaaaata caaattagag aatgttgatt ttaattacaa tgataaaagc tggaaagtaa
    14941 agagcaaaga tttaaattta tctactgacc tggataaaac agtagaaaac gcatataatt
    15001 taaatagaaa gagtgctttc tttggcaatc tatcaaaaac tatttcagca aattttggca
    15061 aaaaaagcaa cttagtagtt gcgataaatt atgataaaaa taaattaaaa gcagaaatgg
    15121 aaaagatagc taaagaaata gatgtagatg taaaagatgc tacacttgat ataagtggtg
    15181 aaaaagtcaa ggttatacca gattctgatg gtcttaaaat ggatatttct aagagtatgg
    15241 agaattttga taatcaaact aaaaaaggta actataaaaa tgagttagta gtaaaagcta
    15301 ctccagcaaa agtaaaaaaa gagcaacttg ctaatataga tacaaattta ggtacgtatt
    15361 caacaacatt taaaacttct caaataaata gaagtataaa cataaaatta gcaacagata
    15421 atataagtaa tgtattactt atgccaggag aaactttctc atttaataaa catacaggga
    15481 aaagaagtaa ggaaaatgga tataaaagtg cacctgtaat aatggaaggt gagatggaag
    15541 aagattatgg tggaggagtt tgtcaagttt catctacgtt atacaattct gtgctatacg
    15601 caggtttaga aattgttaat gtaaaaaatc atactatacc atcaagttat gttccaaaag
    15661 gaagagatgc aactgttgca gatagtggaa tagatttctt atttaaaaat aatctaaagc
    15721 atccagttta cataaaaaat tacgtttcag gaaatcaaat tgtttgcaat atatatggaa
    15781 gtgcagaaga taaacaaaat ataacaatat caacaaaatt agatggcgtt tcacaaacta
    15841 caatgaaaag agttaatgac cctacaatgc ctaaaggtaa agaaaaagta gacaaaagtg
    15901 gaagaaatgc atattctgta tcaacatata gaacatttaa tgatgcaaat ggtaaaaaaa
    15961 ttaaaactga aaaaatagct aattcatatt atcctaagaa ggaaggtatt atattagttg
    16021 ggactatgga accaaaacca gaggaaaaac caaatacaga cgaaaataag aataatcaaa
    16081 atacaaacaa tcaaaaccca aataatcaac aaaaaccaga aacaccacca actgataata
    16141 agcctaatga gacacaacca caaccgcaag cttaaagttc tcaagaatag gatttatgta
    16201 gagtaataaa aaatataaat ctaaatagga gggattactt tgaatttaaa taatataacg
    16261 aattacgttc aaagtatttg cgagaatatt tctaatgtct tggatgtaga tgttacttta
    16321 gttacaaaag atttaactag gatagcaggt acaggaatat tcagaggtaa aataggagag
    16381 acaatatcag agaagtcagt gtactctctt gttttaaaag atgggaaatc ctatgttata
    16441 aataaagaaa tagaagagaa ctgtaataaa tgtgcaaata gagaaaattg taaagagtta
    16501 gctgatatat gtactcccgt taaaatggga gagcatatac ttggaatctt gggtatagct
    16561 gcgtttaatg aagaacaaaa agaaaagata ctttcaaaag ataaggagtt aactgctttt
    16621 gtaaggagta tgtctgattt aatatctttt aaactagatg aactttataa acaagaagtt
    16681 aagactatag atgaccttga gagggaagct atagaaaatg ccataaagaa atatggaagt
    16741 aatacagaag gtatgaaaaa agtagctgag gcattaaata taggtatagc tacactctat
    16801 agaaaagtaa aaaaattcaa cattaaaagt taatagtatt gaaaaagagg taaccttttt
    16861 atgaaaagaa gaggattacc ttttttatta tgagaatggt ggaaaaatat gtatagtttt
    16921 gacttgacat attaaatatg ttatcttaaa tatatatttt agagtggagg tgagtattat
    16981 tttagttaaa gatataaaac aagacataga aagcatgcct agaaaaattt tagatatatc
    17041 tttgatagaa gataataaaa gtgatttgac tttttttaat atagaagaag aagacggtga
    17101 tgaaacatta aaagcattaa aacagagtta tgtgactaca aattataaag aagaaactct
    17161 attaaacttg caaggagctt taaattcaaa gtcagataca acgtctaagg agttaaaatt
    17221 agaatcatat aaaagatata acaatgcatt ggatttagca tataaaaatt atataactag
    17281 tgccattaat atggttaata aagctctgga gataaatcct aaagacattg atatactaaa
    17341 tcttagaggt cttttaaaat tattaaaatg tgattttgct aaatcatttg agagttttta
    17401 tactgcttta tgttatgaaa ataatcatat atctagaaaa tatgtaaatc taatttcatc
    17461 tgaagatttt aaaacttttt taggaagata caatcattct ataagattta taaatgaaga
    17521 attaaattat gagtcaatac atattttaga gaacataatt gaagaagaac ctgaactaat
    17581 agagccatat gtaattttat ctttgttata tgataaacta ggtaatgtaa aaaagagaga
    17641 aggatattta gacaaactta aagagctaga taaagataat cctgtatttg aaaaaaatga
    17701 agaagaaaaa gaagatacaa gtaaaaagga agaaataaaa aaagtaaaaa gaaagaaaag
    17761 tattttgcca tatattatag ttggctgtgt tttaataggt atggggatat atttgattca
    17821 aagcaaaaag agaatagaaa acttgaataa ccaaataagt agtaaagagg aaaagttaag
    17881 tgaaactgat aaaaagttag gagaaacgag taaaaaatta gaaaaaacga ataaggaatt
    17941 aaatgaggtt aaaaataaag aaccagaaag agagataact gtagctgatg aggaagattt
    18001 atattatcaa gctctaaatt taaagaaaaa caaagaatat gaaaaagcca tagataattt
    18061 taaaagtgta gtttcttctg gtaaaactaa aaaatatatt tctgagtcaa tatatcaatt
    18121 agcaataaca aataaattat taggaaataa ggatgaagct ataaaatatt acaaaaaata
    18181 tataaatact tatactaaaa atgaccagta ttatgatgat tcatattacg agttgggtat
    18241 gctttattat gataatggcg atttaaaaaa tgcacaacag actttttata gtttgagaag
    18301 tgaagttcca gacagtatgt ataacaattc aaaaataaaa gaaattttaa gtgaaaaata
    18361 ggtttatata gttaagtttt ttgaaacaac caagtatgta ttttattaaa ttaaaataaa
    18421 aataaattta aaaagagatt gtgtcaaatt ataactttct attttaaaga aagatatttg
    18481 cttgttgata aaactacaaa tatatgattt gaagcaatct ctttaatttt tggaggtgga
    18541 aaatgaaagt tttcaatcaa ttggtaataa ttttatctat ctgggtaata ggagagtata
    18601 taagttcctt tatacaagga attatactta ttcctgggag tatagttggt atgctattat
    18661 tatttctact actacaattt aaagttttag acttgagtag tatagaaaat gtaagtggat
    18721 ttttcctcga taatatggct atatttttta ttccagcagg tgtatcactt ataaagtcat
    18781 tagacctaat aagggaaaat gtattagtgc ttttattagt catatgttta agtacactaa
    18841 tagtaatgta tactactgga attattgtgg agaaaatgat aaaaaagaag gaagaaggac
    18901 aaaaaaatgt ataatgtatt acagacacca gtatttggta taatagtaac aatagttttt
    18961 ttcaatttag gaagatacat tcaacgaaaa acaagtaatc ctatatgtaa ccctttatta
    19021 attgcaatcg taggaataat attgttttta agcatatcta aaatccctta tgagaattac
    19081 aagataggag ctgatagtct aaatttcttt ttaggtcctg tcacagtagt acttgcagtt
    19141 ccactttata aacaatttga attatttaaa aagcatatgt ttgagattat tgtaggaata
    19201 ggttgtggta tagtgatttc ttttgtatct gtattgataa ttggcaaaat agctaattca
    19261 gatgtaagta taataaattc actaattcca aaatctataa caacaccaat gggaatatct
    19321 ttagcaaatt ctttaaatgg tgtagaatca ataacagttg tagccataat ttttacaggt
    19381 atttttggtg gtatggttgc ttctacagta ttcaaactgg ggaatataaa tcatccagtt
    19441 gctaaaggaa ttgctcttgg aacatctgca catgctttag gaactacaaa ggcttttgaa
    19501 cttggagaaa tagaaggagc tatgagtggt gtttctattg gagtctctgg tacaattaca
    19561 gtaatactaa ttccaattat aatgaatttt atataaaaaa taaaattaag atgagtacct
    19621 tgaatactta aaacaaaata aaataaaaaa aatttaaaat aaaaactgaa cgaaaaaaat
    19681 gcaaataatg aaataaaaaa atcatgtact gaaattataa aaagaaaaat ttcatttagg
    19741 aattaattat aaagagacaa ttactaaact tgaatttgct aaaataaaat aaattactgc
    19801 taaaatagat atttagaaaa aaatactata aatttactat attgcaagtt aaataataag
    19861 cagtatcata ttatgctaga aaaagtttca tttaaggcat aaatgagatg atttgaacgt
    19921 ttttaaagat tagaatataa aagattgcac tagacatata tgaaaaagat aatataatag
    19981 atgatgtaat agatgacagt tcaagaaatt ataaaaaaaa tttatttgaa atattatcta
    20041 ttacatcagg aataatatat gtaagagtaa gcttttaaaa ttctaaagat ttagaaagat
    20101 tgaagggaga aagaaatgag tgaagttaag aataccctac aaaaacatcc agttttaaga
    20161 tattcaacaa tgctatttgg gatgttgatg acatctatag gaataaatgg gttcttaaga
    20221 ccagcacatc tgcttagtgg aggtgctaca ggtatagcaa catctataaa ctatttgaca
    20281 aatataaatg taggtttatt aacattttta atcaatattc caatatttat cttagggttc
    20341 atataccttg aaaaagagtt ttgtatttca agtttggtaa atatgattgt attttcatta
    20401 ttattaggag caactcagga aataagtaat attataccta tacatgatat attgcttcaa
    20461 agtgtatatg gtggtatatt atctggttta ggagtcggag ttgtatttag aactaggtct
    20521 tctcaaggtg gtacagatat aatagctgca atactaaaaa ttaagaagaa tatagaaatg
    20581 aaagacactg ctttagcaat aaatggcttg atagtactta caggaagttt tttatttggg
    20641 ttggatttag cattatacac tcttataggt ctatttctaa atgcgtattc aatgagtttt
    20701 attaaagatg caatgaatta ccaaaaatct gttatggtaa tgtcaaatga agtcgattta
    20761 atagcagaag atataatgaa gagtttagtt agaggtgtaa cttttttaga tgcagaaggt
    20821 gcatacactc atcaaaaaaa gaagattata tatacaatag tttcatcaaa tgagatacca
    20881 aagataaaag atatagcttt gaagtatgat aaaaaggcct ttatatctgt aaatgatgtt
    20941 acagaagtaa agggaagagg gtttaaagca aaagatttat agaaaatttt acaagctggg
    21001 agtttataat gtaaatttgt atattatatc tctcagctta tttaaattta gtatacgaaa
    21061 ataaaggttt tattaatgat ttgtgtatca ctttaaaaga tatcatttta aaattaaaat
    21121 tgaaaaaatt acttaatatg tagaaaacat gaccactatt aggatataat aaatttaata
    21181 gatttagtaa aatacctagg aataacgttg gaggaatggc attatgaatt tatctaaaga
    21241 atatgttaat ttgtatgata attatttgaa atatataaat gaagtaaaca aagagattag
    21301 aagtataaag aacatgaaga aacgtgtttt aaaaaggggc gattttgctc cggaaaatga
    21361 agtattagaa ttggaaggaa aaacaatacg cgatatagat gatgtcgata caaaaaaacc
    21421 aaaaaataaa atctataaat tttcaaatgg ggatgtatat gtagggaaat tcttagaggg
    21481 aaagatggag gggaaaggct catatacttt ttttgtagat gaaggaacag ttatggagta
    21541 cataggagaa tttaaagaag ataaaaaaaa tggaaaagga aactttatat tttcaaatgg
    21601 aaatgaatat ataggttatt ttgaggaaga tatgatgagc ggtattggaa atatgttata
    21661 tagtagtaaa gatgaatata ttggaacttg gaaaaacgga aaaaaagatg gaaaaggtat
    21721 ttataagtgg agtgatggat gtatatatgc aggtgaattt aaaggtggaa agatggaagg
    21781 gtacggtatt tgctataata gtaaagggga agtactttat gaaggagaat ggaagaataa
    21841 tttgattcat ggtaagggaa cttatatatg ggaaaaaggt aaaaagtata taggtgaatt
    21901 tatgcatggt aaaaaacatg ggcaaggaac tttttatcta aataatgaat tggtttatga
    21961 agggacttgg aaatttgata agccatctat atttgataga acattagatg aaatattttc
    22021 cttgagactg tagctttatc taattagtag ataaagcttt tttctaatac ttactgtaaa
    22081 taggtatgaa tgatattgat tagtatacac tatcaatatt aacttaataa atgcaatatt
    22141 aaaaaatttt gattgatttt aagaaggaga gatatattga agagattaat tgctttagtg
    22201 ttagtagtac ttattgtttt attttatagt cctgaattat taaaagaagg atatgattta
    22261 aaagaaaagt tttttcaaag tgaaatatgg aatgaatttt tagacaaaat aaatataaat
    22321 gataattcta agaaagataa aaaagaaaaa agtcaaaatt tacaatcaaa taatactgaa
    22381 ggggagaact taggagagtc agatataaag aattttgaaa aaataagctt aggagataat
    22441 ttaagctatg ttttatcaag tatcggcaaa cctggtagaa ttgatattag tgaatatggt
    22501 tttgattggt atgtatataa tcaatatgga aaagaatttg caatggttgg acttgaaaat
    22561 gatgaagtag tagcacttta tagtaattct attaattcat gtgaaaatca agatataaaa
    22621 ctaaatcaag atagacaaac agtgagaact aagattacac cattaaaata taagagaaaa
    22681 ggaaatacca gatatataat aaactcagaa aatcaatatg atataataag taaggaaggt
    22741 aagtatatta caattttcta cgatattcat gaagaaaata gagtttgttc atatttaata
    22801 attgataaaa gcactgaaga tgagtttaaa aatttatatc cagatgatag cgaagaactt
    22861 aaaaaatgtt ttgaacttga agttatagac cttgtaaata gtgttagaaa tcaaagaggg
    22921 ttaaactcat tgagatacag tgaacaggca actttgagtt caagaaaaca tagtgaagat
    22981 atgagagata ataatttttt tgaccatgta aataagaaga atgaaactcc atttgacaga
    23041 atgaaaagag aaggtatagt atatacttca gctggagaaa acatagcagc aggacagatt
    23101 aatgcaatat atgcgcatga agcttggatg aactctgaag gacatagaaa aaatattttg
    23161 gggaactata ataatattgg agttggagta atatttggag gaagctataa aacatattac
    23221 actcaaaatt tttataaata actaaaatat ttgaaaggaa gttaaaaaat gacatcatgg
    23281 aaaaaaaaga cagtatataa gtgcttaata gcagtagcct tgttttgtgg aatagtgtta
    23341 atatctaatt ttagtaaagt ttctgctttg atgatggata ctaatggaaa tgttttgatt
    23401 aaacatggtt caagggaaaa aaagctaata gcaattacct ttgatgatgg tcctcatcct
    23461 aaagaaacta gtcaagtttt agatgtatta aagaaataca atgtaaaagc tacttttttt
    23521 atagctggaa aacatgcaaa atggtataaa gaaccattag taagagcaag taaagaaggt
    23581 cacgagatag gaaatcatac tttcaatcat cctgatataa gtaatttaag ttctagtcag
    23641 atagaagagg agattgttaa gtgtgaagac attttgaagg aagtaactgg gaaaaaacct
    23701 acattattta gaccaccatt cggaagttat agagaaaaag acttaataga aattgcaaaa
    23761 aagcatgact ataaagttgt tttatggaca ggtgtagatg tgaaagattg gaaaaatcca
    23821 ggagctaata gcattgcaga taaaataatt aataaagtac aaaatggaga tataatactt
    23881 ttgcatgatt atgcaactaa tgatacagtt gaagctttag atatgtttat tccaaaaatg
    23941 attgaaaaag gttttaaatt tgtaacagtt tctgagttga taaaataatt tttagggggg
    24001 agatttacag tatgattctt atgatagaca attatgattc ttttgtatac aacctagtcc
    24061 aatatataga agaattaggg gaagcagttg tagtaaaaag aaataatgaa atcaaaataa
    24121 gtgacattga agaactaaat ccagaggtaa ttgtgttatc tccaggaccg tgttctccaa
    24181 aagaagctgg tatttgcata gatattgttg agcattttaa ggggaaaaaa cctatactag
    24241 gaatttgttt aggtcaccaa actattggac atgtttttgg aggagatatt ataaaagcac
    24301 aacagcctgt gcatggaaaa gtatatagta tcaaccatac taataaagga gtttttaggg
    24361 gacttaaaaa tcctttaaat gtcactaggt atcattcact aatagttgac tccaatacag
    24421 ttccaaaaga attagaaatt acagcaatta ctgataaagg ggaaataatg ggaattaggc
    24481 ataagaaata tttaatagaa ggagtacagt ttcatccaga agctattttg tcagagtatg
    24541 gtcatgaaat gcttaaaaat tttataacag aagctagaga aagggtacat atgtaatatg
    24601 ataagagaga taaatactaa attaaattct tttgagatat ttactatttt tagaaatgaa
    24661 catgacagtt ttatattaga tagtgctatg gataaagaaa aattgggaag atattctttt
    24721 ataagtagcc aaccatttaa ggtattaaag tataaagata ctgatgaaaa tcctttagaa
    24781 gttttaaaag aagaactaca taagtatagg gttgtaaatg atactaatct tccatttgta
    24841 ggaggtgctg tgggatattt atcttatgat ttaggtaatt acatagaaaa tttacctaga
    24901 actgctgtag atgatattga gatgcctgat atgtattttg gattttataa tcatgtaata
    24961 gttatagacc atcttgtgca aaaaacttat atagctactc caaacataga tatcgaatta
    25021 gaagaaaaga taatagatga tatagaacaa agaatattaa aagaagagaa aaaaggtata
    25081 gatagcatat gttatgaaga aaaagaagta acacctataa gacttaaatc taattttaca
    25141 aaggaagaat ttaaaaatgc agttcaaagt gttagagagt acataagaca aggagatata
    25201 tatcaagcta atttaacaca aaggttcagt ggagaaacag aacttacaag ctttgaattg
    25261 tatagggact taagaagatt tagcccagca ccatttgggg cattcttaaa ctttgaagat
    25321 gcacatatat tatcaaattc tccagaaaga tttataagat gtgttaataa gagaatagaa
    25381 actagaccaa taaaaggtac tcgtccaaga gggaaagata aagaagaaga tttaagactt
    25441 caacaagaac ttagaaatag tgaaaaagat agagctgaac tacttatgat agtagattta
    25501 gaaagaaatg atattgggag aatatctaaa actggaagtg ttaaagttcc agagctattt
    25561 gtaattgaac catatgcaaa tgtaaatcac ttagtttcca cagttgtagg tgagttaaaa
    25621 gatgataaag atgctactga tgtaataaaa gcaacttttc caggggggtc tataacagga
    25681 gcacctaaga ttagagcaat ggaaattata gacgaattag agccaacgca aagaaatgta
    25741 tatactggtt caataggtta tataggtttt aatggtgata tggattttaa tatagcaatt
    25801 agaacaataa tcaaaaatga caaaaaagtc tactttcaag ttggaggagg aatgacttgg
    25861 gattctgacc cagatgaaga atatcaagaa acacttgata aagctaaatc cataatgaag
    25921 gctttgaggg gatattatga agaataatgt aggttttgat agtagtttaa gtaaatttgg
    25981 aattggtttg tttgaaacta ttagagttaa aaatggaata gcagtagatt tagatatcca
    26041 tatagaaaga atgctaagct caataaattg tttggattta gatataaact ataaaaaaga
    26101 tttcttgata aatgaaattg ttacatatat aaaaaaagaa aatgtcatta ataaagcact
    26161 tagaattact gtttttgatg aaggttataa tatatctatt agggatattc catataatca
    26221 agagacgtat gagaaggggt ttaaattagc tatatctcca atagttaggg ggaatagttt
    26281 aattcataga cataagacta ctaattattt tgaaaacata tataccaaaa atatcgcaaa
    26341 taagactggt tataatgatg gtatattttt aaattcagaa ggtgtaatat tagaatgttc
    26401 tatgagcaat attttcttta taaaaggaga aagagtgtac actcctagtg atagattacc
    26461 gatattaaat ggaataataa aaaaaaggat tatagagatt tgtgacgaat tacatataga
    26521 gttgatagaa aatgaaatta atatatcaga aattagtagt tttgattttg tttttgtcac
    26581 aaatagtctt atgggcgcta taaaggttac agaaattgac aaaataaaat ttaataaaga
    26641 aaatgttgtt tttgataaaa tagtgaagtt attagaataa attaaaatat taacaatttg
    26701 ttggagacaa aagatgatag gttgtattta tgaagtatac aatgaagaga tgactaaaat
    26761 aatagaaaac caaaacactt tggctgtata tttagtgggt tctagtaaag atgtagattt
    26821 tactctttat gatgtagtga taaacgatat tgatgtgttc gtttttgtaa aagaagggga
    26881 aaaacaagag agaatactgt ttaaaaaaaa gggaatagaa tttgatgtaa attacttttc
    26941 aaaagatggt gtaaaaaaat tattatcaaa tagggaatat ttctttgtga aagaaatgaa
    27001 agatgctaaa gtactgtttg atagggagaa tatatcacat attataaaag atataagtag
    27061 agatatttac ttagaaggac ctagtaaaat gtcattagag gaaaagtctt ttataaagca
    27121 agatattgga gcaaaaatat tgaatttaaa aaataaagaa aaatttgatg tttttgaata
    27181 tcattttttg acgaatttat atttaaaaga tataataatt gggtacttta atataaatga
    27241 taaatgggta ccaaaagaca aaaaattgct aaaagtttta aaaaaagaaa ataatgagct
    27301 ttttgaacta gtgtcaaaag taagtgaaaa ttatgactat caaagacttt tagatgttta
    27361 taattatatt tttaaagaaa ttgagacaaa agaggttata aaactaatct tctagtcaca
    27421 aatcaatggg gggagtttaa atgaataaag ttgataaaga aaagatacaa catgcagtaa
    27481 gagaaatact agaggcaatt ggggaagacc cagatagaga aggtctaatc gaaactccaa
    27541 atagagttgc taggatgtat gaagagatat tctctggtct tagtgaagaa ccaagagacc
    27601 atttaaaagt tctttttgca gatgaaaaac atgaagagtt agtattggta aaagatattc
    27661 cattttattc atgttgtgag catcatctag ttcctttctt tggaaaagct catattgctt
    27721 atttaccaaa aggaggaaga cttacagggc tttctaaact tgctagagta atagatacat
    27781 tggcaaaaag accacaatta caagaaagaa tcactaaaaa tgctgcagat ataataatgg
    27841 aagaattaca accttatggt gtcttagtag tagtagaagc tgaacatatg tgcatgacaa
    27901 tgagaggcgt aaaaaaacca ggttcaaaaa ctgttacatc agcagtgaga ggaatatttg
    27961 aaaaggacat tgcgtctaga gccgaggcta tgagtttgat tactatgaag tagtaattta
    28021 ttatagatat aatcatttat tgagataaaa tttaatttaa gggagtgtca ttaattgtgt
    28081 ttgattatgg taaaagaact tatataatgg gaatattaaa tgtaactcca gatagttttt
    28141 ctgatggagg agattttaat aacttggaca tagcaataca acatgcaaaa gatatggttg
    28201 accaaggtgc agatataata gacctaggag gagagtctac acgcccaggt catagctatg
    28261 tagactcaga cgaagagcta agaagagtaa tccctgtaat aaaaaaactt aaacaggaat
    28321 tggatatacc aatatcaata gacacttata aggcagatgt tgcagaagaa gcattaaaat
    28381 taggtgtcac tatggtaaat gatgtttggg gtcttagaaa agataaaaat atggcttctg
    28441 taataggaaa atatgatgca gaagtgtgta taatgcataa tcaagatggg acaaactatg
    28501 acaaagatat aatggagtca ataaaagact tttttaaggt aagtatagaa atggcaatga
    28561 gttgtggtgt aaaaaaagaa aaaatagtac ttgacccagg tgtaggattt ggcaaggatt
    28621 ttgaacaaaa tattgaagta ttgagaagat taaatgaatt aaaagattta gggtatccta
    28681 ttttgcttgg gacatccaga aaatcagtaa taggaaaagt acttccagtt gagcctaaaa
    28741 aaagattaga aggtacaata gctactactg ttcttggtat aagagatggc gtagatatag
    28801 ttagagtaca tgatgtttat gaaaatttaa tggcagctag aatgactgat gcaatatata
    28861 gaaagtaggt ataatataat ggataaaata ttacttagta atctaggatt ctatggatat
    28921 catggtgttc ttaaagaaga aaattttcta ggtcagaaat tctttgtcga catggaactt
    28981 tatattgatt caagagaagc aggtcttagt gacgatataa ataaatctgt aagctatgcc
    29041 gaggtttaca atgttgttaa agatattact gaaaataaac aatttaatct tttggaggct
    29101 ttagcggaaa atattgctga agaagtcttg aataaattta tacttataaa tggagttatg
    29161 gtcagagtta gaaagcctga ggctcctgta aatggtattt atgactattt tggtgttgag
    29221 ataaggagaa caagagatga ataaggctta tttgggaata ggtactaaca tgggtgatag
    29281 atttgataat ttatcaagag catgtgaact tttgaaaaat agtgattcta tatataaagt
    29341 aaaagaatca agcttatacg aaacaaaacc atggggatat acagaacaag cagattttct
    29401 aaatatgtgt gtagaaatag aaacagagtt tgaaccttat gagttgttag aatattgtca
    29461 agaaatagag agagaactac acagagagag aatagttcat tggggaccaa gaactataga
    29521 tgtagacgta ctatttttta atgatgtagt ttccactgat gaaagactaa caatacctca
    29581 tccaaggatt caagatagag ctttcgtttt gataccactt atggatttaa atgaagaact
    29641 tataataaat gaaaaaacaa taaaagaaca tttaaacctc ctatctgctg aagaaagaga
    29701 agaagtaaag gagcttgtag gttatgaaag aaaacctatt taataataat tcaaagatag
    29761 agataaatac aaataacaaa aagataactg taaaaaaaga taaacttata atagctggac
    29821 catgtgcaat agagagttat gagcaacttt tggagactgc taaatttgta aaaagtcagg
    29881 gagcaaatat tttaagaggt ggagcataca agccaagaac atctccaaat tcatttcaag
    29941 gattaaaaaa agaaggtctt gaaatattaa aagcggttaa agacgaagtt ggtatggctg
    30001 ttattacaga acttatggat gtaagagata tggacgaact gtatagtata agtgatataa
    30061 ttcaaattgg gtcaagaaat atgcaaaact ttactctttt aagtgaagtg ggaaaacaaa
    30121 ataaacctgt tatgttaaaa agaggaatag cttccacaat tactgaatgg ataggtgctt
    30181 ctgaatatat agcaatagaa ggaaatagta atattataat gtgtgagaga ggtataagaa
    30241 cgtataatga ttatactaga aatacattag atttagctgc agtacccatt attcaaaagg
    30301 aaacaggtct tcctgttgtg gtagacccaa gccatgccac tggagttaga tatttggtaa
    30361 aacctatgtc actggcatct tttgcatgtg gagcagatgg aataatggta gaagtacatc
    30421 ctgacccaga aaatgctttg tcagatggtg ctcaatctct ttgctttaat gaatttgaag
    30481 atttaatgaa atcaattaat aattattaaa agaggcaaga gcctcttttt tattcgtaat
    30541 cgttgctaag gtaaatttat aagttataat ttgatagtta gattatttaa tataaataaa
    30601 gatttaatat tgatagaatt aatataaaaa ataaaaattt tttgattaat aagaaggata
    30661 tcaataaaaa aagtcgaatt gtgtatattg agtgattgac aaatttagaa tatagtgtag
    30721 aatagaaatg ttaacacaaa aaattacacc agaaggtgat aatatgaatg atataaaaga
    30781 cattattgaa gaaataaaag ctagatgcga tatagcaagt ataatatctg aatatatgaa
    30841 tataaaacaa tctggagcta attacaaagg attatgtcca tttcatggcg aaaagacacc
    30901 ttctttttat ataaatacgt caaaacagat ttataagtgt tttggttgtg gtgaaggtgg
    30961 agacgtaata aattttgtca tgaaaatgga aaatttggat tttatggatg ctgtaaaaat
    31021 tttagcaaat aaatgcggta tagaaattaa cactaacatg aatgaagaaa ctaggattaa
    31081 aatagaaaaa tctaagaaat ttcaagatat tcatacggaa gcagctagat tttatctttc
    31141 aaacttattg ggaagcaaaa atcttgggta tgaatattta agaataagag gactagatga
    31201 taaaattatt aagaaatttg gtttaggatt ttctttggat tcatggaatt cacttatgaa
    31261 tactctaatc agtaaaggat ataaaaaaca agacttattg gagtgcggtc taattgcaaa
    31321 aaatagagat ggaactaatt gctatgataa atttagaaat agagttatgt ttcctatatt
    31381 cgattataga ggaaatataa taggatttgg gggaagagta ttagacgatt ctttgccaaa
    31441 atacttaaat tctccagaca cgttaatttt taataaaaaa cagaacttat acggattaaa
    31501 ttttgctaga aaaaatttag aaagtaaaac tatagtctta gttgaaggat atatggattt
    31561 aatttcgctt tatcagtatg gtataaaaaa tgtagtagca acccttggaa cagccttgac
    31621 tgaacaacaa ggcattttaa taaagagata tgcggacact gctattatat cttatgattc
    31681 tgatgaagca ggaataaaag cgactttaag agctatagat atacttacta aattaggtat
    31741 caatgtaaaa gtgttagact taaaagatgc taaagaccca gatgaatttg taagaaaata
    31801 cggacttagt gattataaaa aagctatgga tgtttctact cactacataa aatataaaat
    31861 agatcatctt aaaaaagaat ttaacattca aaaagatgaa gaacgagtga agttcgcaaa
    31921 agaagcttct aaaattataa aacaattgac aagtcctgtt gaaattgatt tttatacaaa
    31981 gtatttaagc aatcaaatag atattaatgt cgagtctata aagagagaag tttatggtaa
    32041 aaattacaat aagccatata ataacaaaaa tcaaaagaaa atagaagaaa aagtaattga
    32101 aaaagtcgaa gtcagacaag acggaaaaca attagttgaa gaaactctaa taaaaataat
    32161 gttagaagac aaaaaaatta gagaaatagc gttacttaaa gtagaagaaa gtgatttttt
    32221 attgaaagaa agtaaagaaa ttttaaatta catgattaaa aatcaagaat tggacaaaat
    32281 aactattgac aaattgaaaa gtttaaacat atccgaagaa tacttaaaag aattaaattc
    32341 aatttctttg aatagtataa acttagagaa cacaaaagaa atagaaggaa taataacaaa
    32401 tatcagaaaa aactcattag aagagcaaat taatagcttg ttgagagaac aacaagaatt
    32461 agaaaataat aatgatatga aagaggtaga tggtagagtt atggaaattg ctttaaaaat
    32521 agttgagata aataaaattt taaagagctt gtagagaaag gaggtttgag tgtggaaaat
    32581 aaatcgaata aaaaagagtt aaaaaaggtt actgctaaga cattaataga aaaaggaaaa
    32641 aagcaaggtt ctctgacact tgcagagata atggaagctt tttcggagac tgaacttgat
    32701 aaggatcaag tagaaaatct ttatgagact ttaggaaatt tgggaataga aataacagaa
    32761 acaaaaaact ataaagctga tatagatttt tcggttgctg atgacgattt aagtataggc
    32821 cacttagatg aagatgcaga ggcaatttca catgatgact cttctgcaat agaaatagaa
    32881 actgtggatt tatctttacc aaaagggata agtatagatg accctgtaag aatgtactta
    32941 aaagaaatag gaaaaattcc tctacttaaa ccacatgaag aagtagaatt tgctagaagg
    33001 atgcacgaag gtgatgagat agcaaaacaa aggttagttg aagcaaactt aagactagtt
    33061 gtaagtatag caaaaagata tgtaggaaga ggtatgcttt tcttggattt aatacaagag
    33121 ggaaatttag gtcttataaa agcagtcgaa aaatttgact atacaaaagg atataagttt
    33181 agtacttatg caacatggtg gataagacaa gctataacac gtgctattgc agaccaagct
    33241 agaactataa gaataccagt tcatatggta gagactataa ataagctaat aagagtatca
    33301 agacaactac ttcaagaact tggaagagat ccaaaaccag aagaaattgc aaaagaaatg
    33361 gaaatgacag aagataaagt aagagaaata atgaaaatag ctcaagaccc tgtgtcttta
    33421 gaaacaccaa taggagaaga agaagatagc catttaggtg actttattcc agatgatgat
    33481 gctccagccc cagcagaggc agcagcatat tctttattaa aagaacaaat agaagatgta
    33541 cttggttcat taaatgatag agaacaaaaa gtattaaagc ttagatttgg tcttgaggat
    33601 ggtagagcca gaactcttga ggaagttgga aaagagtttg atgtaactag agagagaata
    33661 agacagatag aagcaaaagc actaagaaaa ctaagacatc caagtagatc aaaaaaactt
    33721 agagattatt tagactaaaa agatacatca ttgatgtttt tgtgataaat gccatgagat
    33781 aagtgatatc tcatggctat tttgtagtaa agatttaatt ttatttttgt agttatttca
    33841 gtctaatatc tataacttgg attaaatcct ataaataaag ggaattgaaa ggagaattat
    33901 atttgaaatt aacagataga ttattgaaaa tagcatcatt agtgtcagat ggtaaaaaaa
    33961 tagctgatat agggacggac cacggataca taccagtata tttgttaaaa gagggaaaag
    34021 taccatttgc agtgctagcg gatgttaata aaggacctct tgacaatgca cataaagaag
    34081 tcatacagaa caatctttta gataaagttg atttacgatt gggttctggt atagagatac
    34141 ttgaaatagg ggaagtagaa gaagtgataa ttgctggtat gggtggaatc ttgataagtg
    34201 agcttctcga ggctaaaaaa gaagtagcac ataatgtaga aaaattaata ttacagccaa
    34261 tgcaagcaca agaagaactt agatattacc ttttaaacaa cggatatgaa attttagaag
    34321 aagttttagt gagagaagat tttagaatat atgagataat tgttgccaaa tatacaggta
    34381 aaaatactat aatagaagat gagatatatt atgaggttgg aataaagctt ttagaaaaca
    34441 aagattctct ttttaatgat tttatagaaa aaaagataaa gacatatagt tctatagtta
    34501 ataaattaga agggaaaaat ggggaagcta tagataagaa gagaaaggaa agcgaagttg
    34561 caataaaaaa acttgaaaat ttaataaaat aaataggagg tatatatgct attaaagagt
    34621 ctaactagaa aaattgaaaa aaagtatcct ctaaacttag cagaggattg ggataatgta
    34681 ggtcttatag ttggagattt tgatatggat gtaaaaaagg tattggtatc tttagaagct
    34741 aatgaagatg ttattgatga agctatatcc aaaaatatag atttaattgt gacacatcat
    34801 ccttttatat ttgggaaaat taataaaatt aatagtggag atttaaaagg cagacttatc
    34861 caaaaactta ttaaaaatga tatatcactt tattctatgc atacgaattt tgatatagca
    34921 tttgatggtc taaatgacta ttttatggaa attatggaat ttggtaattc aaaggtttta
    34981 gatataacta aaagcgaaaa tttgtataaa ttagcagtat acgttccaca taactattca
    35041 gatgaactta gaaaggtttt aagtaattca ggagcaggtc atatagggaa ttatagtgat
    35101 tgtacgtttt caatagaagg tgaaggacaa tttaagccat tagaaggctc taatccgttt
    35161 cttggaagtg taaatgatat agaaactgta aatgaagtta aaattgaaac tgtagtacca
    35221 cagaagcttt taggtggggt aataagttct atgttagatg cacatcctta tgaagaagtt
    35281 gcatatgatt tgtacaagtt agaaaataaa ggtgagatat ttggactagg tagaataagt
    35341 aaacttgata aaagtatgac attagaaagt ctttcaagga aaataaaaga gaaattaaat
    35401 atgaaacaca taagagtagt tggaaacctt agtacagaca taacgaaagt agccgttgta
    35461 acaggagctg gttcagaatt tgtaaaaaaa gctaagagac aaggtgcaga agtactaatt
    35521 acgggtgatg taaagtatca tgaggcacaa gatgcacttg atattggaat gtgtatagtg
    35581 gattgtggtc attttgatac agaagatata ttcaaaaatg ttatgaagag atttttagat
    35641 gaatttagtg aaattgaagt aataaaaagt aatgtatatt tgaatccatt tagtactatt
    35701 tagcagtgtt tgataataaa aatactatat aaaaaataaa tttgagttta attaggggga
    35761 taatgatgaa agtagcagta atttttcata gtgtttgtgg gagtacatat ttattagcta
    35821 gagaatataa agaagcgctt gaagaaatga atatcgaggt agatatattt agagtaagtg
    35881 acgaagttgc aaaaacactt cctcaatatt atttgataaa ttccaaagaa tacaaagacg
    35941 aatttgaaag tataaatgta attaaatctg gaaaagaaat attagattat gatgctatat
    36001 ttatgggttc accaacatat tatggaaatg tatctggacc aatgaagatg tttatggata
    36061 gtttttctga tatttgggta ggtactcctt tgagtggtaa aatatttggt tgttttgcta
    36121 cagcaggttc acaacatgga ggaggagaat tagctttgca agctatgaat atatttgccc
    36181 aacatatggg aatgactctt ttgtcagttc catgttcagt aagaggaggt tatccagcgt
    36241 atggaatact tcatatagca ggagataatt ctgatataag accaaatgat gatgccaaga
    36301 taggtataag agattaccta aaaagactta acatataaga atatcatata aaaataccta
    36361 aaagcgactg tatatacttt taggtatttt tacttaatta taaacgtgaa gctttaccag
    36421 aaatatggtc aatttctatt ttaacaacag ttgttaagtt catatccttc tctatgtact
    36481 tcatgccttc ttcaaagaat cctttagaat atttttttat tatttctaca agagcatttt
    36541 tcttttcttc attttctaca gtgcaagctt ttccaaaaac tatagcacta gaataagtag
    36601 tactaaattt atctggaata acactttcat tagcaactac taaaaaagaa actttgttgt
    36661 ttttcgatat attatctaac ttatgcccat ttcttgcaca atgaaagtaa atagaatcat
    36721 taaagtatac ataatttaca gcaactccat aaggataacc attttcagat atagtggaaa
    36781 aagtaccaaa ttcaccattt tttaatactt caacagtatc ttcttttgtc atttctcttt
    36841 ttttcaatct catttcttta aacataatat catcctttct aattttgatg cttaaattaa
    36901 attttagaac atttataaag attatgctat gttttttaca aattttaaga aaaaaatata
    36961 gtttaagata aaaggtagtg aaagagaagc tatttggagg tttatttatg atattattgt
    37021 tagagtagta taaacaatac taataaattt aatagctggt ttcttgttat ttaagatagt
    37081 aagcatgtct ataagaaggg gaagttatcg agggtagaag ttgttattta taactatatt
    37141 ataaagaaaa tattattata taaaataata aatagtaaag aggtatcaag ttgaatataa
    37201 tacttaatac ctcttcaaaa ttaagttata aaagtgttgt gggaattgtc ctatacatgg
    37261 taaggagata ataaagaatg tatctttaaa gtctcaacta aacagcaaaa tttatccaac
    37321 aaacatacaa taaatgcttc tttgtatcta ggtggcttaa cagtaagtgg ccacatgtgt
    37381 tttaaaatta tgtccgtttc tttttcattt atttgaaaaa ataaagttgc attttttaat
    37441 gcttctctag ggtgagtaaa tccatgtaat ccttttctat cacctttgta atgccaatca
    37501 taaagaaaaa agtcgtgtag taaagctcct ctaataacac tttgaatatc aacacttaag
    37561 tgcaattttt tacataatag ataactataa tatgctactg acaaactatg ttcaagacat
    37621 gaaacattgc catgatgagg aaatgttctc ataagttgaa ctttttcaga agaaagtatc
    37681 tcagaagcac attcattaaa atatttgatt tcagcttttg acaacattat gaaaatctcc
    37741 attcttagta atatataaat actatacttc aacgataata tgaaatattt cttatcctac
    37801 aaaatataat acccaataat acaagtaaga taccttttat ggtattttaa agtaagagag
    37861 attttattag gctaaacaat gaaaaaatta aaagtaaagc tatagcaata tatagtattt
    37921 ttccaagagg attgccaaaa tttatagtcc atccaatacc aaacctttta ttaaccatta
    37981 atgatgggtc atttggatta ttatacatga tgcctgctat ccaatacttc tcatcttctt
    38041 ctggagaata agatgagttg aattttaaat ttggggaatt aatatatgtt gctattaaat
    38101 aaattataac taaaagcgtt gtaatattca tagcagttga tagttttgtt tttattgata
    38161 aaagagtagt aaaaaactgt gttgtcatta taatcatcaa tattaaaaac aaataaccaa
    38221 ttttatttaa atatttaatg ttttcaactc tactttcttc aattctattt gtatctatct
    38281 taatccttga ctttatggat ccaatggaag ttatatataa taaaaccatt aaacaaaagt
    38341 cagtaccgat taatttaaat acattaagaa atgatttatc tataaaaaca tcaggagacc
    38401 catttatgtt ccaatgagtg gcaattgagt ctggcaattg attataatta aatgctataa
    38461 aaatactcat tcccaaagta aatagtatcg gtattaaata gattatttta aattttttta
    38521 ttattttatt tttcttattt ataaaatcca tatctactat taattttgaa tctatatcta
    38581 tatgacctaa tttagaataa atttctgatt taagcttctt agctttttta tgtgtatgaa
    38641 tatatagtat actttcatat aataaaaaac ctataatacc aataaaatag gaaagttcca
    38701 atttattaaa tgtaaagacc agaataaaaa ctaatataaa gtctataata aaacctaaag
    38761 ataatagttt tttaaattct ttatctaact ttataaagta attataattt ttatgctctt
    38821 ggtctataga aactccatag atgtgttttt tacctacaaa atagggcata aaataaaatg
    38881 tagcatacat caaaattaga actggaaata ttgtaaatag acattcaatc ttactcataa
    38941 tatttcacct catacttgtc aaataaactt gaacttagtg acaaaaattc ttctttacta
    39001 atacctgata aataagattt tgccaccaat aattccaagt caagtttatt tttttgacga
    39061 gttgtattat ctattttcat tggtagttga gctacaatag caccttttct tctatcaata
    39121 tttaagaatc cctcttcttt taattcattg taggatttgt tcactgtatg taaatttaca
    39181 ccaatatttt cagccatact tcttacagat ggaagtgatt catttatttt caattctcct
    39241 gaagctatag ccttagttat ttcttcttta atttgtacat aaatagattt atcactatta
    39301 aaatctaaat ttaaaaccat aaaaaacctc cattatgctt tataaatgaa aacgattgtt
    39361 atatacatag tataacataa aaaataataa caaacacaaa atataagttt atattttgta
    39421 aaaattgtaa tttaaaaaat aacataattt ttattaaaat aatacagata ctatttatag
    39481 atagaaataa aaattagaaa ggagaaaaaa tatgttaaca tatttaatga aaagacaaat
    39541 gcataaaaaa gatgatggaa tgagtaaacc aatgatgatt acaggagctg taattacagg
    39601 tgtaggagca tatgctgtat ataaaatggt aaaaagccat aaatctaatt ctcaaatggt
    39661 caatacaaat tattatggaa atagcgatta tgatgattat aaatatgacg aatttgatta
    39721 tgactgtgat tgtagagaca caaaacaaga ttatgaatat gaagaattaa aaaaaaaagt
    39781 aaaagaattt aattcaagaa gaataaattg tgaaaattgt ccacatgttt ctcaagaaga
    39841 aatgatgcaa tatgtaaata gtgttaaaga tgtaaaggaa gagattgatt tacatgaaga
    39901 tgctaaaaaa gataatattt acaaagaaga tgaatacaaa aaatatgaag aagaataagt
    39961 aatattttgt ataactgaac aaatagtaat gtcaaattat ttaatatcta gttttaatat
    40021 gtaagttgta acttaacttg aaagaatcag tatcattctt tagatagtta agtaacaact
    40081 tacattttat ttttataaat tttaatagtt ctttgtgact attttgtaat tttagaaata
    40141 ttttagtatc cagggtaatt gtgtataata aaacttgtat agatagatag tatgaaatta
    40201 agcagatagt ttaaaattaa aatgaaaaga aaggaaatag ttatgttaaa gttgttgata
    40261 gttgaagatg atagtactat atcttttgga ataaagtatg ctttagaaca agaaggattt
    40321 agtatagata tatcaaagga tttatctagt ggaaaagaaa tgatttcttc taatgaatat
    40381 agcatgatac tgttggatgt tacattgcca gatggaactg gttatgagct ttgtcaatat
    40441 ataagaggat tctctcaggt tcctataata ttcttgactg cttgtgatga agaagtaaat
    40501 attgtaatgg gtctcgatat aggtggagat gattatataa caaaaccttt tagaattaga
    40561 gaattaatat ccagaataaa agctgtttta agaagaaaag gtaatacttc agaagaaaat
    40621 aagaaaatac ttaaatttgg agatttaagt atatatacat tagaagctag agtatataaa
    40681 aatgataaag aaatatttct gacatcagtt gaatataaac ttcttttaat tcttatacag
    40741 aataaaaata ctgttttaag tagaactcaa atattggaaa aactttggga tgtaacttat
    40801 gattttgtaa acgacaatac tctaactgtt tatataaaaa ggcttagaga aaaaataggt
    40861 gatgatttat gtgaaccaat ctacatagaa actgtaaggg ggattggtta taaatggata
    40921 ggaagtgaaa atagtgtttc tatataatcc agaagtgaag aagtttttaa gtaagtatgt
    40981 tactttgatg tttattgtta tcataatatc tattggattt agcataatca acgtgtcctt
    41041 aactaaagag atggttgtaa gaaataatca ggctataata ggaactttat caagcaagta
    41101 tccaaacttg gaaagtcaga tagtagacat aataactcaa gggaagtcta tggagaacat
    41161 agattatggt cagaaaatat taattaagta taattatgat aaatctatta ggataaactc
    41221 tgagcctatt atttctaaat tagttttaga gactatcaaa ataaatataa tattagtatg
    41281 tataatattt attttgatat ttgtgttggt tgttagatat tttaagtcaa tttacaatga
    41341 tttatcagat atgactaagt atgtttacta tagttcagag ggtaagccat ttgatatgaa
    41401 aaacaagaat caagaagggc agataggtct tctaaaaact gaactcttaa agatgacaac
    41461 aattcttaat gaaaaggttg aacttttaaa aagagaaaag atatttttaa acaatacaat
    41521 ttccgatata tcacatcaat taaaaactcc tatgacttct ttaataatgt tgaatgattt
    41581 attatataat gatgtaccat acgaagtaaa aatcgatttt ttaaataaga taaaaaatca
    41641 attaaataga atggattggt tgattaaaag catgcttaaa ttatcaaagg tagaagcaaa
    41701 agtgataaat tttaaaaaag ataaggtaaa atttagtgaa ctcatacata gagcaatgct
    41761 atctatgaaa atacctatgg agattaaaaa tcaaaaactg actatagagg gaaatgataa
    41821 tgtatcttat attggtgata ttgattggtc cgtggaagca ttagtgaata taatcaaaaa
    41881 ttgtgtagaa catactcctg aatttggaaa tataattata acctataaag aaaatccatt
    41941 attttctgaa ctaataataa aagatgaggg tgaaggtata gataaaaaag atataccaca
    42001 tgtatttaaa cgattctata gaggaagaag tagttcaaaa gaagatagtg taggaatagg
    42061 tcttgcaatg tcaaaatcta taatagaaag ccaaaatggc gatatatatg taaacagcga
    42121 aaaaggtcag ggtacagaat ttcatataat atttcataaa atgtatgata gtgactaatc
    42181 tgtaatattt aattcacttt atagtaatag ccaaaaccta atatatgaag tatagaatat
    42241 aaatattgga ggtagttatg gaaattttaa gagtagaaaa tctaactaaa agttatggta
    42301 aaaatgaaac aaaagttgat gctataaaaa atgtaagttt atcagttgaa aaaggaacgt
    42361 ttatagcaat aacaggtcca agtggaagtg gtaaaagtac cttattacat ttattaggag
    42421 gagttgacag accaactagt ggtaaggttt atataaatga tgttgatata tataatttaa
    42481 aaactaagga tttggcgata tttagaagaa gaaatatagg tcttatatat caattttaca
    42541 acttaattcc agtcttaaat gtgaaggaaa acatattgct tccagcagag cttgacaata
    42601 gagatattga tagagaatat tttgatgatt taatgaaaac attaggtcta attgatagag
    42661 aaaagcacct tccaaaccaa ttatcaggag gtcaacaaca gagaacctct ataggacgtg
    42721 cattaattaa tagaccttct ataatattag cagatgagcc aacaggtaat ttagatagta
    42781 aaaattcaaa ggaaatatta gaattgttaa aattgtcagt aaaaaaatac aaccagacac
    42841 taataatgat aactcatgac aaaaatatgg cacttcaagc tgatagaatt ataagcatag
    42901 aagatggaat cataaaaagt gatgaggtga tgtagatgaa tttatataca ttactaacca
    42961 ttagatactt aaaacaaaat aaaagaagaa ccattgtaac cataatcggt ataatacttt
    43021 caacagcttt aatttgtggt ataggaaata tatttgaaag ttttatggat tatcaaatga
    43081 gagaaactat aaagaatgat ggaagtttcc atgttacatt ttatgatgta aatagaaaaa
    43141 atgtggaata tgtaacgaaa tcagctgaaa tagaaaaaca tgcatttacc aaacaacttg
    43201 gatattctaa attagaaaat agtgaaaatg ctatattaag tataaagcaa tatgataaaa
    43261 atgcaataaa tggatataaa gtttctataa aagaaggtag atttccagct aaggaaggag
    43321 aaattgttct aagtgaaagt attattaatc ttatagatga taagttaaaa ataggagata
    43381 agataacttt aaaagtaggg gatatgtttg actcaagcaa gaaaaagatt gatagtatga
    43441 catttcatga aggtgattat atagcaaatg aaaaagatag aacttttaaa gttgttggta
    43501 taattgaaaa acctgggttt gaacgttata atggaattgc aacagctata gcctacttta
    43561 atcctatgaa taattacaat gatacaatta atgtatcagt agcagtaaga aatcctaaag
    43621 atgtgtataa gataagtaat aaaataagta aaaatatata ttcaaataaa gataaagaag
    43681 cagtttctga tatgataaaa tacaatgaac atttattgag gttacaaggt gctagtaagt
    43741 attcaaatat aaataactct ataaagtcta taattatagc agtaactatt ttagtaatca
    43801 tatgtacaat tgctacagtg tacaattcct ttagtatttc tataaatgaa cgaaaaaaac
    43861 agtttgggat attaaattct ataggtgcta catctagtca aattaaaaga ttagttttta
    43921 tagaaggtat tataattagt ttaattggta taccaatagg actaatatct ggaacagtag
    43981 ctatagacct attgtttaaa attataaata agtattttac tgaatcggtt gttactaaga
    44041 tgagtttgca gatagtgtat aatccaataa taactattgt tagtataata atagttttgc
    44101 ttacaatctt tatatcaatt ctactacctg caatatcggc ttctaatatt tctcacctta
    44161 atgtgattaa aaatactgga gagtataaag tgggcaaaat caaaagctca agacttatta
    44221 aaatgatttt taaaactgaa ggagtacttg catataaaaa tattaggaga aatagaaaaa
    44281 aatttataat aactcttttt tctttaatgg taagtataat aatatttata tcttttagtg
    44341 gctttacatt acttttacta agaggtgaag aaattagaaa ttctcaaaga aaatatgatt
    44401 tgtatttaac tgcaaagaac acagctaggt ctgtagagga tactataagt gaactagaag
    44461 atattgatgg gataaaaaac tttgaattgg caacaggaca atatgtgtct ataagagtaa
    44521 gtgaaaataa aataaataaa tccaaggaag atttaatcag gaaatattat caaaaatata
    44581 agattggaga tagttatgaa tatgatttca gtaataatga attaattttt ccaggagatt
    44641 ttgcagtaaa aaacaaaata aataacttag tacagggctc ttttaataaa gagagagcaa
    44701 ttgaagaaaa tggtgttata ttagttagaa aaagtgcatt tgaagaaaat gggaagaaag
    44761 gtgtagtaga acttaccaac tataaagtag gagatacagt aaattgtgaa tatcttgatg
    44821 aaaatgcctt aagtaaaaaa gtaaaggtca agattcttgc tataactgac gaagaacgtc
    44881 taggtcttgg ttatcaaaat atggggttac aatttataac ttatgatgaa gttgctaaaa
    44941 atttaaattt aaaattaagt aaaagcctta tatttattga ttcaggagga agcattaaga
    45001 ctaagaagga aatagaagct ttggcaaata aaaataattt taacttttat gatgaaagtg
    45061 caagcaatga aagtgaaaaa caagatttaa aggttattaa aatatttgta tatggtttta
    45121 tagtagtgat atctttagtg agtgttacaa atattctaaa tacagtaagt acaagtataa
    45181 atctaagaaa aagagaactt gcagtaatac aatctatagg ggttactcct aaaggattta
    45241 ggaaaatgat atatttagaa agttttatat atggtatact gtcattgttg tttggaatac
    45301 caattagtat tggtataatt ctaattatga ataaacttat ttcaggtgta attgaatttt
    45361 ctccgattat accgtggaca gccatagtta tctgtatagt aagtgttttt ataataactt
    45421 ttatagcagg gtatatacca atgagtaaat taaataaaga aaatataata gataatataa
    45481 gaagagaaag tatatagata taaaaataat tcttaactat ataaaatatt attaaaatca
    45541 tttaagtggt ataaaatatt attatatcac ttaaatgatt ttttatttat ataagaaatc
    45601 taataataaa ttactagagg tatttaacta tttagaaaga attggtatta tataaagtaa
    45661 gagaatatat aataagaaag aatatttgat tttattggaa aacaaaagaa aaagaaggtg
    45721 attactattt ctcatataac tgcgaagaat atgtataaaa gtttagagga aagaataaac
    45781 aagtttccac aaggtgctcc accatctgat acattataca aaatactaaa tgtactatat
    45841 acagaacaag aagcgaagtt agttgctcag cttccaataa agcctttcag agtaaaaaca
    45901 gcagctaaaa tttggagtgt aagtgaaagt gaagcatata gagtattgga taaacttgct
    45961 agtaaggctc tgatactaga tatagaagat aataaaggga agaaatatat aatgcctcct
    46021 ccaatggctg gtttttttga gtttgccatg atgagaacga gacacgatat agaccaaaaa
    46081 cttttggcag agctttacta tcaatatatg aatgtagaag aagattttat caaagattta
    46141 ttttattcaa cagaaacgaa gcttggaaga gtatacgttc aagaggaagt tttaactaat
    46201 gataatgagg ttagtatttt agattatgaa agggctactc atataattga tgaatcaact
    46261 catataggta taagtatgtg ttactgtaga catagaatgc aacatgttgg aaaagcttgt
    46321 gatgctccta tggatatatg tatgacgttt gacaatgtag caaattcttt aataaataat
    46381 aaatttgcaa gacgtgtgga taaaatagaa tgtaaagaac tacttcatca agcatatgaa
    46441 cataacttag ttcaatgtgg agaaaatgtt aggaaagggg ttacgtttat atgtaattgc
    46501 tgtggatgtt gctgtgaagc aatggtagca gctaaaagat ttggaaatct tcatccagta
    46561 cagacaacaa gttttatacc aaatataaac catgaaaatt gtgtaaagtg tggtaaatgt
    46621 ataactgcat gtccaataga tgcgataagc aaggttaagg aagatggtaa agaatatata
    46681 aaaattgatg aggatagatg tctaggttgt ggagtttgtg ttagaaattg ccataaaaat
    46741 agcattatgt tattaaagag agatgaaaaa ataataactc cagcaaattc agtacataga
    46801 gcagttctta tggcaattga aaaagggcag ttacaaaatt taatttttga taataatgct
    46861 ctggctagtc atagagctat gggagctata ctgtcagcta tattaaagct tgaaccagct
    46921 aaaaagattt tagccagtaa acaattaaag tcagtatatt tagataaatt gttaagtatg
    46981 aatgataaat agaaactaac ttaaaaaagg caaagtttta gacttatcta tatcttaata
    47041 aacttatcat ttaatattta aatttaattt ttacacatat aaaacttata acttaaataa
    47101 aaaaaggcta tattcaatta atattacttg aatacagcct tttttagtta tgttaagcta
    47161 tttcttttat ttgcttaaat gagttttcat ttccatttcc accaatttgt gttacagatt
    47221 taaatctcat agttttaaat agttcttttt gattataatc tagtgagttt cctactagca
    47281 ttacaggaga tttagttttt ccagccaaaa ctccaacaga taatccgtct attaaatcat
    47341 cttgtttatt cattccattt ttagcaacat ataaattgtc tatcttagaa tccttgtaaa
    47401 attcttttat tacttttgca ttagtttcat ttctagtgct acctgatatt ctctgtggat
    47461 tttgaagttt actttctata tttttagaaa ctgtatattc tccaccgatt acataagatt
    47521 tatcaatctt tttgttttta aacaagttat ttatttcagt tatattacta ttttcattag
    47581 taagtattat aggcatatca ttttgagctg atacagctcc aatgcttact gcatcggcta
    47641 atcctttttc gccattaact actgaaatct ttgatatatt gctaatattg ttcaattctt
    47701 tagcaatgtt catagaagtt tgatatctat cacttcctga aattctagat acagagatat
    47761 tgtttgattt tatagtatct aaagattttt catttataga agcttctcca ccaactacat
    47821 atacattttt aacttttaat ctctttaatt cagccaaagt tttttcattt atttgagagc
    47881 ttccagtcaa taatatagga gcgtttttct tgtatgcaaa tggtgttgca gccaaagcat
    47941 ctgcaattgc tgaatcgttt attaaaactg cattttcagc attttcccaa cctgcttgac
    48001 ttatcttaat agaagtttca tatctatcag ttcctgtaag tgcacttgca tttacttcat
    48061 cttgatatgt aacctcaaat ctagcatttg gacttcctaa gaaaacaatt acgcctcctt
    48121 ttggcaatct aactctattg ttctttgtaa ctaaagaata gtttacagga acacctttat
    48181 catcataaac agcaaaagct gaattttgag gaagattaac ttctattttt ttatttgcga
    48241 tatcgtcacc aatcttatac cattttgcat aaccattgga ttctagttca caagtaaaag
    48301 atttttctgc tggcaaatta gttatagaat cttcactaac atacgttagt gttccaaaag
    48361 ataaatactc tgtaccattt tctttatgaa gtttaatgtc ggataaatca cgacctatta
    48421 caccaggtat ttctataaaa gcatttgagt tattctcatc cattatttta gtgttaacta
    48481 tataacctgg agtttcatca gaaagactaa aacttgcttt tacagagcca aacatatagc
    48541 tttgagaagt atatttttca tccactagat agtaaccttt gccacttctt tttttccaca
    48601 cttctttgac actatttgat atattgttgt catctacttt ttgagctaca tagtataaac
    48661 ttgctgtctg acctaatcca gggacatcat cataagagct catatttaaa tatgtgatat
    48721 tatttttttc ttttacaaat tttaaacaac tattaccttt ttcagataca aatctatctt
    48781 gacctatgta tacgtattta tcttcaggtc cattttctat ataaggagaa gatactgtta
    48841 aagtaccatt atcattaaca tctactttta tcatatttga agaagcataa agaccactat
    48901 tttcttttaa agagctaggc attttaactt gttgtggctt actaaatgtt ttatcaggtt
    48961 ttatttcttt aattttacct ttttctttta atgcagatag taagatttct tgtccaatta
    49021 tttcattaag ttgactactt ccaccagaag aaagaactgc aactgccata ttttcatctg
    49081 gaagaactat aagattactg tggaataata aagaatctcc accttttgta agagctttta
    49141 aattatactg attaaatgga taagtgttga cacaatccca ccctaaacca tatccaagta
    49201 tagagtcttc tccttcaggc catagaccat ttaaatattc tttgttttcc atagctttta
    49261 ctgaagcagg agaaagaata ccatttgaat ttttcataaa tgtttgtgca aatgtacata
    49321 gattttctgc acttgaatat aaaccacctg cacctatagc attaaggtta tcttgtggaa
    49381 ctgcatcttc ccaataaggt acatatgctt ttgctagttt tgaactatca aaactatttt
    49441 ctggagtttt tgtattttgt aagttaagtg gattatttat gtatttatca agaaaattag
    49501 taaatgacat accagatact ctttctacta aaatttcagc taaagtaaat ccatcattac
    49561 aataaacaga aaaagctcct ggtttagctt ttaatctttg tttttgtaat tcttttaaga
    49621 aattatcatg accataagaa tcattgtctg ctaataaaat agtgttttta aaactacttc
    49681 ccatcaaccc tgatgagtga tttaataaca ttcttggagt gatttccttg tatctatcat
    49741 cagccatttt aaattcaggt atatacttta caacaggagt atctaaattt aattttccat
    49801 catcaaccaa cttcataaca gctgttgtag taaacatttt actgatagat gcgatactat
    49861 acatattatc cttatttaag tttttgttat cctgtttgct gtaaactcca ccattaccag
    49921 aaatctcaat tttgccatta tcaatcaaag catattgagc acttacagca ccatactttg
    49981 atagcaaagt ttggattttc tctttagcaa gagctttagt ttttgtgtaa gattccgcgt
    50041 ttttactata atcatgtaat tctatatcag aactttgata tttttcggaa ttatcttttg
    50101 tattatcagc aaaagtaata tttggagcag cagtaaataa catactcaat actaatgtac
    50161 tagataataa tttagagagc ctttgcttaa acatattaca ttacctcttt ccctttttaa
    50221 taatttataa ttagcataac attcttaatt attttaatca acagattatt atcaataaaa
    50281 aaagctttta taagtatagc tttttatata acagagaaaa atataaaaat aatatttgtt
    50341 gttgtataaa gaataaaggg tataggtaat atataaataa aatggaggaa ttttagacat
    50401 atgtataaga atataaataa gaagcaactt aaagaaatga tgaaaaatga aaaggatgtt
    50461 ttattattag atgtaagaac taaagatgaa tttaaggaat ataaaataga aaatgctata
    50521 aatatatctt tacaagagtt aatcaataat atagatgaaa tttacgatta taaagataag
    50581 aaagtagtag tttattgcag aagtggtcat agaagtgtta ctgcatgtaa tttgttagct
    50641 gaagaaggtt ttgagcattt atataattta aattcaggaa taattgatta tatgagttaa
    50701 ataatgtaag ttatacatta aatactatgt atagctctgc ttattaagta ggaatatatc
    50761 taaatattta taagataaat ttaggaaaga acgaattttt tcgttttttt ctatgacagt
    50821 ttttgtagta aatattagtt tttaagttgg aaaaaggtag tagcttttta gctactacct
    50881 tttaatatga acttagaata ttattaaaaa aatatattta aagacagaat taatttttta
    50941 atgaccagtt aaattactat cgccgaattt atcattaaat ggttttataa ctctatttat
    51001 aggtcctttt agaagtacat ttaaacaaat agacagaatc ataaatagta atagaactag
    51061 tatatcttta gttagatttg gagcatatat accaccaact gcttcccttg tagcacctat
    51121 tgcataggta aatggcatta tagggtttat tctttggaag aatgtaggtg taacttgtat
    51181 agggaatgta ccaccagaag aaccaatctg aacgactaat agtactattg caattgcttt
    51241 tcctacattt ccaaatacag aaactaaaga atacactata aagttaaata ccatactagt
    51301 aaacataagc agaactatca ataaaattgg atgttttgct gttactccta acaataatat
    51361 atctccagtt cctattataa aaccttggac aagagctata cttaaaaaag taaggcctct
    51421 tccaaagtaa atttcataag gtttatagtt tccatgtaca gatgtagaca atagtgctga
    51481 aataagtaat ataccaaccc atgtagaaag aacactataa aatggtgtca ttgcagaacc
    51541 ataattttca attggatata atttctctgt tttcacctca acaggttctt ttaagaaatt
    51601 agactttgtc aatatatcac tttcaagcaa gctgactaat tttttcatat cttcaccatt
    51661 actaattttg cttaaagtat caatcaaatc atccaacatt ccttttgcta aaggaagtct
    51721 ttctcttatc aatgatatac tttcctgtgc atttcctgaa agttttagag aagtagtaag
    51781 tatttcttca acctttggaa gttttgcttc tgccttatct aaaacagtaa ttatatcatt
    51841 tgctactttt atactgtttg caaatatact atttataggt tttgatattt ttgagtcaaa
    51901 attatttaaa atatttaaat taattcttcc aataccattt gatagactta aaacattatt
    51961 caaagcactt atagatggtt gttgtccaga tataactttg tttttaatat catttaatgt
    52021 tgatatagat gaatctattt tattgctaga gtcttcaaga ttatctatga catcatccaa
    52081 tctattattt gatgtaagtt ggtttaattt agttaaaaaa tccaccaaag tatcatttaa
    52141 agattgcaaa ttagaaagtt tttctgataa attatctatc aacttaggta catcttcact
    52201 gccactattt actgcatcaa ttaaatttaa tgtaagagaa gaagcagaag atgaaaggtc
    52261 aaccattaaa tttaagtcag acttaataag aggagaaagt tcgtctaaat tatcatttgt
    52321 atcctctaag aattttttta agtcacttga taatagtttt gtatcattca gagtcttttt
    52381 aattgtaggt aaatcagatt taatatcttt aactgtatca gataattttg aagtagcatc
    52441 agaagctaaa tcaacagtct tatttatatg gtcaaatctc ttttgaaggt caataaggga
    52501 attttcaact tttgtcaatt ttggaagact gtgttcaatt cctgcaccaa ctccgtttga
    52561 tataccaaga acgatttcac taactgtttt tactatagtc tgattaacct gtagttgtat
    52621 tgtagaagca cctttatctg taatctttgg tgcaactgca tttatttttt cattaacagt
    52681 atagataatt tcgccttttt taacatcatc tgtaattaaa gatgtcaaat cttttgtaaa
    52741 attttttgga atcttaagtg atgcataata agtacctttt ttaacacctt caagagcagt
    52801 tttttcatct acaaactgcc aacctaaact cttgttatct ttgagttgtt caattaattg
    52861 gtctcctaca ttaatctttt gtcctgctat ttcatttcct ttatcttcat ttgttactgc
    52921 tacaagcata ttagcagtgc ttccataagg gtcccaagat gcctttatat tgaaccaagc
    52981 atacagagat ggtaaaaaag caagacctaa aactattaca agtacggcat aattgccacg
    53041 tatatctttt aggtcacttt taaaaatttc taatatattt tttaaaccct ttgaaggtct
    53101 taaattcttg atattattcc agtttaaaat ttcttttaaa ctattagttt ttttcaaatg
    53161 tctcacctcc taaaatattt tgataaagaa aaaagttaga tttataatca attttaaatt
    53221 atattacttt ttacacaaat agtaaagtta aaattttgtc ttaattttaa tacatatata
    53281 ttatatataa tagtatgcta taaatatata taaatatagg aaataaaaac aaataattta
    53341 taaaatatat ggtataaaaa ttaataataa atcaaatatt tataattgat ataatcaatt
    53401 aaattagcca ttatgatata cttttggtaa tgagaaaatt ctatgaaggg atgattgaat
    53461 gaggtatttt aaaaaataca taaaaaaata tatagtatta tttctaacag cagtattttt
    53521 tttaacattg gaagcttttt gtgatttagc tcaaccaact ataatggcaa aaataataga
    53581 tataggggtt tcaaataaga acttagacta catactatca acaggagcta taatgatagg
    53641 tataactttt ttaggtgcaa tatttgcaat aataagaagt gtaatctcgg caagagtttc
    53701 tcagcatttt tcttatgatt taagacagga tgtatttgaa aagataaata catactcatt
    53761 aaaacaaata gataaatttg gtagagcttc attaataaca agaattacta atgatatcaa
    53821 tcaaatgcaa caattcgtta atggaatgat gagagttttt ataaagtcac caataatgtg
    53881 tataggaagt ttaattatag ctataaaatt aaatttaaag atgtcaataa ttattctaat
    53941 tgcagtttta attatattta ttataatatt gcttaatatg aagatagggt atagattatt
    54001 taaaaatgta caagaaagta cagataaagt aaattcaaaa ttaagacagt ttttaagtgg
    54061 aataaaagta gttaaactat tttgtagata cgattatgag aaccaaagct ttgaagagtt
    54121 aaatgatgaa ctttttaaaa atagtagaaa agctacaact atgatgtcat tttttagacc
    54181 gacaattaca ataatcatta atgtttccat aataataata ttactgattg gaaggcattt
    54241 aatttattca ggagaaatta aaattgggat tatagttgct tatgtaaact atatgactag
    54301 aatattaaca tctcttataa tgatttcaca tgtttttaat gtttttgtta gggcaaaagc
    54361 atcttatgag agaataagtg aggttttggt tgatgagaat gaagaagtaa ttgagagaga
    54421 agaaagttta gatgttggag aaaaagattt aaagtttgta aactgtgata taatttttga
    54481 aaatgtagat ttttcgtata acaaaaatac agatgaaaaa atattaaaaa acgtatcctt
    54541 taaaatagaa gaaggtcaaa atattggtgt gattggtcaa actggttcag gaaagacttc
    54601 tttagtaaat ttaattcaaa aattatatat aattgataaa ggtgatatta agattggagg
    54661 acgtagtata tacagtattt ctgaagaaag tttaagggca agaataggtg tagtatttca
    54721 aaatagtagt gtgtttggaa aaagtatatt ggagaatgta gttatgggaa atagagatat
    54781 atgcaaagag gatgttgtaa aatcatgtga aatagcaaat gcaaatcaat ttataacaaa
    54841 actcgaaaat acttatgatg aagttttatt ccaaaggggt aaaaatttat caggaggaca
    54901 gagacaaaga attactatag ctagagctat agccaaaaaa ccacaaatat taattcttga
    54961 tgattgtttt agtgcaatgg atattaatac agagacaatt ataagaaaga atataaaaga
    55021 gtatataagt aatttaagag aaaaggaaag taagaaatgt actgtaataa ctatttcaca
    55081 aaagattagt tctataattg actgtgataa gattttagtc ttggatgagg gtgaggtggt
    55141 tggatttgct acacatgaag atttactggt tagttctcca atttataaaa aaatttttgc
    55201 gttgcaaaat ttagtaagtg aagatgtaaa ttaaggagga agtatattga atttaagtac
    55261 tggaaatcag aaggtcagta gattaaagaa aaaagaaaag cctaaagatt ttaaaaaaac
    55321 gtttaaaaga atttttatgt actttaaaaa agataagaag attactagat ttattttttt
    55381 gctagtaata attgattcaa ttatatcaac tgtaatacca tatactattg gaaaggtagt
    55441 tgacataata gatatcgata cttattcaaa atccattttc ttaaaaggaa taattatttt
    55501 actttcattt tatataattg agttttcagt taaactgtct aagggaatat gtacagctag
    55561 attatctcaa agtatagtca gagaaatgag aagtaattta tttttaaaat ttaaaaatct
    55621 accaataacc ttttttgata aaagttctac tggagatatt atgagtagag tgacaaatga
    55681 tgtcgataat atcagtacag gaatatcaaa ttcattagta cagttaatta caggaatctt
    55741 aaacatattg atgactttta ttatgatgtt tgtattaagc ccaattttaa ccttttgcag
    55801 tgtaatatta ataccgatag taatgtttgt gagtaatttt attgcaaaga gaactagagt
    55861 tttttttaag caacaacaag ttgagttggg aaaactaaat gcacatattg aagaaatgat
    55921 atcaaacata aatgtagtaa aatcttttaa ttatgaaaga aaatctgtaa atgattttaa
    55981 agaagtcaat gatagacttc taaatatttc ccttaaatcg caaatttaca cttctctttt
    56041 aatgcctatt atgaatgtga ttagtaatat aggatttgca actatatgta ttataggagg
    56101 cattcttgca tctaaagata ttataaccat aggggttata gctagttttt taagttatgt
    56161 aagacaattc acaagacctt taaatgaatt agcaaatcta tttaatacat tactttcagc
    56221 catagctgga tgtgaaagag tttttgaaat tatagatgaa caagaagagc aagaagtgca
    56281 taacatgttt aaaagtgaga ttaacgataa taaagatggt aatttaaact ctcattttgt
    56341 aaagggagaa attgagctta aagatgtaag tttttcttat gattcaaaaa agaaaatttt
    56401 agataatata aacctaaaaa tcaaatctgg cacatcaaat gccatcatag gagagacggg
    56461 aagtggaaaa acaactatta taaatctaat tacaaatttt tatcatatag atgaaggaag
    56521 tatattttta gatggtaagg atatatactc tattaacaga aactatttga gaacttgttt
    56581 tggagtagtt ccacaagaag gttatatatt caatgataca gttatggaaa atataaggta
    56641 tggaaatctg gaggctactg atgaagaagt tatatatgct agtaaaatag caaatgcaca
    56701 taaatttata gttaaaatgc gtgaaggata tagtactgta ttatcggata ggggtgaaga
    56761 tttaagtgaa ggtcaaaaac aattaataag tattgctaga gcagtattaa aaaatgctcc
    56821 aatacttatt ttggatgagg ctacaagtaa catagatata gcaacagaag ctaaaattca
    56881 agaagcaata aataatttaa cttatggaaa gacaagtata attatagctc atagattaag
    56941 taccatatca aattgtgata atataatagt tttagaaaat ggtagaattg tggaatcagg
    57001 aaatcataaa gaattgataa aattaaaggg acattattat agaaacatat tattgacaca
    57061 gggaaaataa gtatttagaa aaaactttta aaaaaattgt ttaaaggtat atggtgcggg
    57121 tatatataga ctaacttaat aaataaaaaa tttaatttga tatataaaat ttaggaggaa
    57181 agtaattatg aagaaatttg tttgtacagt atgtggatat atacatgaag gagatgctgc
    57241 accagcacaa tgtccagtat gtaaagttgg agctgataaa tttgaagaaa tgaaaggcga
    57301 aaaaaattgg gctgatgagc acagaatagg agtagctcaa ggtgtagatg aagaaataat
    57361 cgaaggatta agagctaact ttgttggtga gtgtacagaa gtaggaatgt atttagcaat
    57421 gagtagacaa gctgatagag aaggttatcc agaagtagga gaagcttata agagaatagc
    57481 tcttgaagaa gctgaacatg ctgctaaatt tgcagaactt cttggagaag ttgtagttgc
    57541 agatacaaaa gaaaacttaa gagttagagt tgatgctgag tatggtgcaa ctgatggaaa
    57601 attaaaatta gctaagaaag caaaagaatt aggattagat gctatacatg atacagtaca
    57661 tgaaatgtgt aaagatgaag ctagacatgg taaagcattc ttaggattat taaatagata
    57721 ttttggaaaa taaatttaat ataaagtaga ttttaggagt atctcactta caatttttaa
    57781 agttatgagt gagatatttt ttaattattt gtactttatt ttttatttct aacgattata
    57841 tttttaataa tagagaataa tttaatagta ataatgcaca acttttaaaa ataaatgatt
    57901 aatccaaaaa taaatttgat tttagaaaag taaattgaca tgtaaagaag aatatattaa
    57961 actaagtata aaaaatttgc tgttttgtaa aggtggtgga taatctgata aagtatatac
    58021 ataaaagtta tgtagctatt gttgttttac atgaaatcta tgggattaat agctttatag
    58081 aagatgtttg tcaaaagtat tataaatatg gatatgatgt attttgtcct gaacttctgg
    58141 gagaaaaaag agtttttcca tattcaaaag tccaagaggc atatgatttt tttataaata
    58201 atgttggttt tgatatttat aaaaaagttg aaaagcttat aaatgattta aaatcagagt
    58261 ataaatatgt atttgttgct gggtatagtg tgggagcaac tattgcatgg agatgcagtg
    58321 aagattcttt ttgtgatggc ataatttgtt gttatggctc tcggattcga gattacatgg
    58381 atgtaattcc aaaatgtcct accttattag tatttgcaaa gcacgattca tttgatgttg
    58441 attctatttc ttaccaactt tctaggaaac aaaatatcca aattgagatt ttagatgcaa
    58501 atcatggttt tatagataga tattcaaata attattctga tattcaaaca aaagtattta
    58561 ctattaaaga aaaaagtttt ctgtctaaat atttagcatg atttagatta ttataaaata
    58621 tatagaaaga tttaattaat ctgaaaagtt tttatgacac tattgatatt taaaatatta
    58681 gtagtgttat tatatttttt gaaataaaat taatcactag aattatagtg ttagttgtgc
    58741 ttttatgact tataagaaac taatattaga tagtgtattt aaatagataa taataaattc
    58801 attatagttg aataagaata ttatatgaga atattgcaat ttgatatatt taccattaca
    58861 ataaaagtag ttacaactag aaaaccaaat aagttaaagt aagttggcaa attggaggtt
    58921 tttaaatatg aaagcattta aaaagcactt cttgatactt tctttgatat ttttacttat
    58981 tatatcatgt tttaacaata tactatgctt tgctgatgag tctgaaaatt caaaaaaaat
    59041 aagagttgga tattgtgatg actacggaat aatatcctca tcaaaagagc attcttatac
    59101 aggatatggt tatgattatc taagagaaat ctcaaaatat acaagatggg aatatgaatt
    59161 tgtaaaaggg tcttgggaag aatgtttaga cagactagaa aaaggtgaaa tagacttact
    59221 tggaccttta cagaagaatg atgaaagaaa taaactattt aattttccta aactaaattc
    59281 aggatatgaa tatagtgtac tatatacaaa agatagtaac aataatatgt tttatgaaga
    59341 tataagttcc tttaagggaa tgagagtagc tgtacttaga ggaaactttc ataatattgc
    59401 atttgagaag tatagagaag aaaataattt ttcagttgaa tatatctact gtaattctat
    59461 tgatgaatta attgagtctg tcaatgaaaa aaaggcagat gcatttgtct gtggaagtat
    59521 tataaatgct aaaggaatga aaatagttag caaattttca gtagagcctt tttattttgc
    59581 tactgcaaaa tataaaccta atttggtaaa agaattagat tatgctttaa aagaattaaa
    59641 aataaatgat atgtattatg agttggaatt atataaaaaa tatttcaaaa gagaggtcaa
    59701 taattccata gcatttactc ggcaagaaat gaattttatt aaagcaaacc caaaacttac
    59761 tatggtatat gattcagagt ggtctcctgt agagtattat gataaggaaa gcaattcgtt
    59821 taaaggtata agttccaatt taatgtcaat tatatcaaaa aaatgtggta taaaatttga
    59881 atatattaaa acaaaaaatt ataatgagag tcttgattac ataaaaagtg gtaaggcaaa
    59941 tatgctatgt ggctcaatca atgaaaatga taaggcaaaa cgatttaata tgaaattgac
    60001 aaatccatac ataaatattc caatgattat ggtaggaaaa ctggatacca atctcaataa
    60061 tgatttaaat attgctttaa cgagtagtta taagtctatc gattcttata tagaaaaaag
    60121 ttttgaaaat gctaagacaa catcttataa gagtatagaa agttgtctaa acgctataaa
    60181 tgaaggtaaa gcaaacttaa tgatacttag ttcttatcag tttgatgaac ttttaagaga
    60241 aggaaagagt gagaatttat ctgttatatc tgttttagat acaagctatg ggatgcgtat
    60301 aggggtatca aataaaactg accctatatt agtatctatt ttaaataaat caatagacaa
    60361 aattactgaa gaagaattaa gtgattgtat atattctaat actattgaca aaccttataa
    60421 agtaccattt ggtgtgattt ttaaagaata ttcaatacaa attatttctt ttgtatgtat
    60481 tttattctta attgctatta aatatataat ttataataaa aagaagaaag aggattatct
    60541 aaagaagata gcatatacag acccattgac aggagcagat agtatagata aatttaaaat
    60601 aaattcgaat aaactgtttg ctaaaaataa tccagaagaa tatgcattgt tttatataga
    60661 tgttgacaaa tttaaatata taaatgatat gtttggatat gatatgggaa atgatacttt
    60721 gatacatata tcaaatacta ttgcaagtga attaaaggaa gatgaaattt ttgcaagagt
    60781 ttctgctgac cattttgttc ttcttattaa gtataagaca gatgatgata ttaaaacaag
    60841 gttaaacaat atttacaata aggttcaaat acttagtaat cctaaaataa actattataa
    60901 attgatttta gattgtggta tatataaaat aagtaaaagt gataatgaca taaatactat
    60961 tatggataga gctaatactg caagaaaaac tataaaaggt ggtcataaaa attcatttgc
    61021 tttttacgat aaggaaatgc ataaaaaaat attaaaagag aaagaaattg aaaattcaat
    61081 ggtagatgct cttaataatg gagaatttat tgtttatttt caacctaaat atagtctttc
    61141 agattatcaa attatagggg cagaggctct tgttcgatgg gataatccac aaaaaggtct
    61201 aataccacca atagaattta ttcctgtatt tgagaggaat ggttttattg taaatattga
    61261 tttctatgta tttgaggaag tgtgtaaaaa gattagagaa tggatggatg aaggacaaaa
    61321 agtagtacct atatctgtaa acttgtctcg aatgcatttt gtaaatagta attttataga
    61381 gaagtttaaa ttaattgtag ataaatacaa aattccgaca agacttatag aattagagct
    61441 aacagaaaca gcagtattag ataatataga agggttactt gatacaatga acaatttgaa
    61501 agaaaaggga tttgtaatct ctatggatga ttttggtacg ggatattcct ctcttaatct
    61561 tttaaaagaa ttgcctgttg acatattaaa actagataga gcatttttta cagaaaaaga
    61621 tgagagtaat aatgaaaaaa ttgttatatc taatgtcatt aaaatggcaa aggaattgaa
    61681 aatgaaagta atatcagaag gtgtagagac tatttcgcaa gtagaatttc taaagcaaat
    61741 tgggtgtgac atggtacaag gatatttgtt ttctaagcca atgcctgtaa aagagtttga
    61801 aaaaattgct tttaaaaaag aataaagcaa tgtgtaagta atgatatata taataaaggt
    61861 gctttaatat tagttgagta tactatttta gagcatcttt atttttgtat taatttttac
    61921 gattttatta ataaaataaa tcaaatgaga aaaaaaatca aaagaataca ataatcactt
    61981 gcaaaaaata tactattgtg atagacttaa atcaaaatta ggaattgtaa aaagaaggaa
    62041 aaaataggat attattttaa tagattaaga tttaaggtat tgtaatttat atataagata
    62101 acgattgctt gtagatttaa attagtttaa gaggagggat attatatgat gccattgata
    62161 ctatcaaata caggtgaaga agtagttata aagaaaattt caggaagtga taagacgagg
    62221 acttttttaa atagtatagg ttttgtagta ggtacaaatg ttaaaatagt ttctaagata
    62281 gatggtaact taataataga cgtaaaagat actagagttg cattagataa aaaaatggca
    62341 agtagaataa taatataggg aggtaatgac atgaacagac tgaaggatat taagtgtgga
    62401 gagactgtaa aagtcaaaaa gttagaagga gaaggagcta cacgaagacg tataatggat
    62461 atggggatta caagaggcgt taatatattt ataagaaaag tagctcctct tggtgaccca
    62521 attgaggtaa cagtcagaga ttatgaacta tcaattcgta agtcagatgc agaaaaaatt
    62581 attgtggaat aataaagatt aattagagta gagttaatgt aattatataa tgagaatgat
    62641 tttctatatc atgaatagtg atgtatttaa ataataatgg agggaatgga aatgtcaata
    62701 aaaataggtc tcataggaaa tcctaactgt ggtaagacaa caatgttcaa tgggcttaca
    62761 ggctcatcac aatatgttgg taactggcca ggagtaacag ttgaaaaaaa aggtggaaaa
    62821 ttaaaaggaa ataaagatgt ggaaatagta gatttaccag gtatttattc tttatctcca
    62881 tatacattag aagaagtagt tacacgtaat tttatgctag atgataagcc ggatgcagta
    62941 ataaatattg tagatgcatc aaatatagag agaaatttat atcttacaac tcaagtttta
    63001 gagctaggta taccgaccgt tatagctctt aatatgatgg atattgtaaa taagaatggt
    63061 gataagataa atattaaaga actatctgaa gttataggtt gcccagtggt agaagtaaca
    63121 gcagttaaag gtcaaggaat tatggaggct gctgaaaagg cagttgaact tgcaagtagt
    63181 aacaataaat taaatttcaa attacccttt gttgatgaaa gtaaggatgc aatagaaaaa
    63241 attgaaaaaa taatagaaga aaagactcca tatatagatg tagaaacacg ctggttagct
    63301 ataaagctat ttgagagaga tgaaaatgtt atacaaaaac ttgatatttc taaaacaata
    63361 ttgaatagta ttgaagaaat aactagaaat tgtgaagatg aattggatga tgatagtgaa
    63421 agtataataa cagccaatcg ttatgaattt attagttcaa taatttcaag tataataaag
    63481 aagaatcgaa aaggtaagga aactgtatca gataagatag ataagattgt aacaaatcgt
    63541 atactagcat tacctatttt tgcacttata atgtggggag tttactatat agcagtaagt
    63601 tcattgggta ctatagcaac tgattggaca aatgatgtac tgtttggaga aattattcaa
    63661 ggcaatgtaa gtaattttct agcttcttta aatgtagcag agtggttaca aggacttgta
    63721 gttgatggtc taattggtgg agttggagca gtactaggat ttgtaccaca aatcatgctt
    63781 ttattcttat tattatcaat attagaagat tgtgggtaca tgtcacgtgt agcttttata
    63841 atggatagaa ttttccgtaa gtttggtctt tcaggaaaat catttatacc aatgcttata
    63901 agttcaggtt gtggagttcc aggagttatg tcaactcgta ctatagagaa tgatagagat
    63961 agaaaaatga ctattatgtt aactacattc attccatgtg gagctaagat tccaataata
    64021 gcattatttg caggggcatt atttggaggt gcttcatggg tagctccatc aatgtatttc
    64081 ttaggtattg caatgataat catttgtgga attatattaa agaaaactag tttatttgca
    64141 ggagaaccat ctccatttgt tatggaatta cctcaatatc atattccaag tgcaaaaggt
    64201 gttttaatac atatgtggga tagaggaaaa gcatttataa tcaaagcagg aacaattata
    64261 tttgttgctt gtggagtaat ctggttctta caatcattta attggtcatt acaaatggta
    64321 gatgctggag atagtatatt agctagctta ggaaatatag ttgcaccaat atttgctcct
    64381 cttggatttg gaaattggca atcatcagta gcaacagtta caggtctagt agctaaggaa
    64441 aatgtagttg gaacatttgg agttttattt ggtatatcag atgcaacaga gcaagaccca
    64501 acacttcttg cttcagttgc aagcatgttt acagtagcta gtgcgtttgc atttatggca
    64561 tttaatatgc tttgtgcacc ttgttttgca gctattggag ccataaaaag agaaatgggt
    64621 tcatggaaat ggacatggat tacattagga ttccaaactt taacagcgta tataattgct
    64681 cttcttataa atcaagttgg aagtttagtt ttaggtactg gaggaagtat tgctggggca
    64741 ataatatcta tatttatagc agtagcagta gtctttgtag ttttaactta ttcaaataaa
    64801 aatatgaaaa aagaaaaaat gggtaaatta agttatatga aaaattaatt catataaata
    64861 aggagtgatg aatatggcta catttattat agcagctatt gtagtagtat taatggcact
    64921 agctgtaatg tatatggtta aaaattcaaa aaagaatggt agcagttgtg gatgtggttg
    64981 ttctggatgc tcaagtagta agagttgtca tagcgctaag agataaatag gataagagcc
    65041 tgataaaaag ttaaattgct ttattatcag gttcttattt tttgtataaa taacaaattt
    65101 catatttgaa gtaggttaga ctatgctgta attttactgt ataattatat ataaatatat
    65161 gattaggagg gattattgct aaattaagca atataagtga atattatgtt taaatttgat
    65221 gttacaaacg agcttatgtg tatagcaagg ggaagtggta aattttttgc aaaaaaaggt
    65281 gctatggtag cctttaaagg aaattttaat tttgaaaaat tgctgttagg tccaagtaat
    65341 ggcggtggat tgggaagagc attattaggt catgttcaga ggtcattgac aggagaacaa
    65401 atgccaataa tggtggttga aggtgaaggt gaaatttacc tagctcaaaa tgcttaccat
    65461 gtagatgtaa tatcaattga cccaggtgat tccatttatg ttgagagtga aaacttattg
    65521 gcattttctg aacaattaaa ttacagtgta aaattgattg gttcaggggt aatatctcaa
    65581 aaaggtcttt ttactacaca tttagtaaat aaaacaggtc aaaatcaaga tgttgctata
    65641 ataacagatg gtaatcctct aattcttgaa ggaccttgtt gtgttgaccc agatgcatta
    65701 gtagcttgga ctggaagaga accatatcct aaagtatcaa aactatcatg gaagactttt
    65761 attggtcaga cttcaggaga atcttatcat atggaatttg ttgaacctgg acaaatagtc
    65821 attatacaac catctgaaag attgtctggc ttaaaaacag attctacacc ttctgataga
    65881 atgagttcag gtggattaag acttggcata gattaaatct tatgatatag cttaattatt
    65941 atttaagata ttaaaaaata aaaagggtag cagggataga tatgttaaaa ggagttttat
    66001 atgtttgaga aaattcataa aaggcttaaa ggatattata tttttttaat aattttaatt
    66061 ttatggaaga tagtatgtgt tttgggtata tggagtagct atattctgcc tcctcctgaa
    66121 atagtcttag atacttttat aaaaatgata tatgacggtt ctattttctt aaatgtttat
    66181 gccagtgtaa gaaggatatt aataggtttt ttaataagtt cattgatggc tataccactt
    66241 ggagttttat ttggagtaaa taaaaaaatg tatgaatatt tcaaaccact atttgaattt
    66301 atgcgaagta cacctccact agctttggtg ccaatgctta ttttatggtt tggtataggt
    66361 gaagaatcta aaattataat tattattttg gcatcctttt ttccaatatt tttaaataca
    66421 ttgaaaggta taaaaaattg tgacaataaa ttaatagaag taggtaaatc ttttaattta
    66481 tctaaaaaga gaatttttta taaaataata atccctaatt ctatgctgga tattgttgtt
    66541 ggacttagtt tagggcttgg gtatagtttt agggctataa ttggagcaga gcttattgca
    66601 gcttcttcag gactaggata tttgatttct gatggaaaag atatgtctag aactgatgtt
    66661 gtattggtag gaatttttgt tattggattt ttaggtatac tttcagatta tctattttca
    66721 aagataataa caaaatttag caaagggaag caggttgatt taaatggtta gaagtggatt
    66781 tttgctagag aatatatata agaaatattt agttgataat aaagagcatt tagttcttga
    66841 taatatatct ttaaatatat ctagtgaaga gataactgtt atattaggtg aaagtggatg
    66901 tgggaaaaca acgctactta gaattttagc agggcttgaa aatgctacta gtggaaacat
    66961 atattttttt aataatgata aaaagtgtac tccaaaagta ggaatggtat ttcaagaaag
    67021 tagacttatg ccatggctga atgtaagtga aaatatactt ttacatactg aaaaagataa
    67081 tagaaataaa gttgatttag acaagtattt aaaaatgatg aagcttgaaa agtttaaaaa
    67141 ctcatatcca aatgaattat caggaggaat ggctcacaga gtaagtatag caagagcact
    67201 ttccttcaat cccgatattt tgctgatgga cgaaccattt gcagcactag attacttcac
    67261 aagaagaaaa atgcaaaaag aagttgtaaa tatccataaa aatactaaaa aaggtgtagt
    67321 atttgtaact cacaatattg aagaagctat ggaaatagca aagaaaataa ttgtttttag
    67381 taaaaataaa aggattaaac aatttagtgt cgaagatgaa tataatagag atttaactaa
    67441 aaactattat ataaacttga aaaaagaaat attaagggaa ttgggggagt tttaattgat
    67501 taaaagaaac aaaaagattt tagcagtaat gacatcttta ataatggtgt tggttgggac
    67561 tgtaggatgt tcaacaacaa atgataagaa agatgaacct gcaaaaaaag aggctagttt
    67621 acctaaggaa ataaatttaa cttatgtaaa atcaccactt aatgttccta gtatattaga
    67681 aaaaaaggat gatttatttg gaaaggaatt taaaaaggac aatataaaag tcaatttcca
    67741 tgaattgaca acaggaccag agcaaactca agcattagca gcaggtgagc tagacttttt
    67801 acatgcatta ggaggaacgt ctgcaataat agctgcatca aatggtgttg gtcttaaaat
    67861 tacgaatatt tatagccgtt caccaaaagg atatatgctt ataactaata atgataatat
    67921 taaatctata aaagacttaa aaggtaaaaa aattgtaggt ccaaaaggga ctatacttca
    67981 tcaactgttg attgctgcac ttgctaaaga aggctatact atagatgatg ttgaatatgt
    68041 aaatatggat attcctagtg ctgcttctgc attagaaagt aaaagtgctg atgtagcaat
    68101 gcttgcaggt ccagtggcat tgaaaacgat aaattcaggt gccaaaatga ttgtaaatgg
    68161 agaaggatta gtaagtggaa taatagttac tgctgtaagt gatgactttg ctgaaaaata
    68221 tcctgaatta gtaaaaagat ttatgaaggt tcatgaagaa actttaaaat atatgaatga
    68281 aaacaaggat gaagtgatgg atgttgtatc taaagaagtt ggtttatctt tagatgaaac
    68341 aaaagaaatg tattcttggt atgactttag ttctaaaata acggacaagg atataaaaga
    68401 attagaagat acacaggaat ttttgatgtc taatggaatg caacaaaaga aaataaatat
    68461 taaagatatg ttgtacaatc aaaattagaa tactttaaaa tattaaagtg gaaaatacac
    68521 ccttatttat tatggaaact gtatggtaaa agagggtgta tttttattat tatacaaaaa
    68581 cacaattaaa aacagcttac tattttatct acacttatgt agtctagtaa ttttctcatt
    68641 ttcttacggt gaagtaaaaa cttcgaatat gtgtcctcgg attgttttgt gtcaccataa
    68701 actttccaat atttaatcat agaaacttca taattactat atcccataaa tccaatcaca
    68761 tctttaagag gatatcctaa aaaaatacct atttcatcag gaaaaacatc actcttaagt
    68821 ttatctacta aatgctctaa ataagcatta acattcgtat tttgtttgta tcctaaaaac
    68881 tttaaaaagt ttactgtttt tttacatttt aatttttctg ataatgcttt tttatttaca
    68941 aataagattt ttaatccctt tttttcttta tcaataacta taaaatctat tttcttacac
    69001 ttatatagat atttataaat atcattaatt ttttcctctc tatttacatc agtaaacgaa
    69061 atatttatta tttcagcagg tttagagcct aaaaagactg gacctaaaac ttctaaaagc
    69121 cattttatat atgatgattc aattttattt ttacaacaaa attgtgaatt acaacaagac
    69181 ataaaagata acctccttca aa
//
LOCUS       DAGQVA010000011        68745 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.011, whole genome shotgun sequence.
ACCESSION   DAGQVA010000011 DAGQVA010000000
VERSION     DAGQVA010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 68745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68745
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.011"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(130..324)
                     /locus_tag="MIV85_000851"
     CDS             complement(130..324)
                     /locus_tag="MIV85_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960220.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(633..2162)
                     /gene="lysS"
                     /locus_tag="MIV85_000852"
     CDS             complement(633..2162)
                     /gene="lysS"
                     /locus_tag="MIV85_000852"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBY2960221.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2177..2656)
                     /gene="greA"
                     /locus_tag="MIV85_000853"
     CDS             complement(2177..2656)
                     /gene="greA"
                     /locus_tag="MIV85_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBY2960222.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="MIV85_000854"
     CDS             complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="MIV85_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBY2960223.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3870..4640)
                     /locus_tag="MIV85_000855"
     CDS             complement(3870..4640)
                     /locus_tag="MIV85_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBY2960224.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4659..5249)
                     /locus_tag="MIV85_000856"
     CDS             complement(4659..5249)
                     /locus_tag="MIV85_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBY2960225.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5433..6401)
                     /locus_tag="MIV85_000857"
     CDS             complement(5433..6401)
                     /locus_tag="MIV85_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBY2960226.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6394..7371)
                     /locus_tag="MIV85_000858"
     CDS             complement(6394..7371)
                     /locus_tag="MIV85_000858"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBY2960227.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="MIV85_000859"
     CDS             complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="MIV85_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBY2960228.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="MIV85_000860"
     CDS             complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="MIV85_000860"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBY2960229.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11261..11689)
                     /locus_tag="MIV85_000861"
     CDS             complement(11261..11689)
                     /locus_tag="MIV85_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBY2960230.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11706..12512)
                     /locus_tag="MIV85_000862"
     CDS             complement(11706..12512)
                     /locus_tag="MIV85_000862"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBY2960231.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12714..13199)
                     /locus_tag="MIV85_000863"
     CDS             complement(12714..13199)
                     /locus_tag="MIV85_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBY2960232.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="MIV85_000864"
     CDS             complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="MIV85_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBY2960233.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14054..14734)
                     /locus_tag="MIV85_000865"
     CDS             complement(14054..14734)
                     /locus_tag="MIV85_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2960234.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14718..15608)
                     /locus_tag="MIV85_000866"
     CDS             complement(14718..15608)
                     /locus_tag="MIV85_000866"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBY2960235.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15726..17276)
                     /locus_tag="MIV85_000867"
     CDS             complement(15726..17276)
                     /locus_tag="MIV85_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBY2960236.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17370..17636)
                     /locus_tag="MIV85_000868"
     CDS             complement(17370..17636)
                     /locus_tag="MIV85_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBY2960237.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="MIV85_000869"
     CDS             complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="MIV85_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBY2960238.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18728..19666)
                     /locus_tag="MIV85_000870"
     CDS             complement(18728..19666)
                     /locus_tag="MIV85_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBY2960239.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19776..19937)
                     /locus_tag="MIV85_000871"
     CDS             complement(19776..19937)
                     /locus_tag="MIV85_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960240.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19947..20444)
                     /locus_tag="MIV85_000872"
     CDS             complement(19947..20444)
                     /locus_tag="MIV85_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBY2960241.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20559..21269)
                     /locus_tag="MIV85_000873"
     CDS             complement(20559..21269)
                     /locus_tag="MIV85_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBY2960242.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21445..21975)
                     /locus_tag="MIV85_000874"
     CDS             complement(21445..21975)
                     /locus_tag="MIV85_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960243.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21992..22222)
                     /locus_tag="MIV85_000875"
     CDS             complement(21992..22222)
                     /locus_tag="MIV85_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960244.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22237..23631)
                     /locus_tag="MIV85_000876"
     CDS             complement(22237..23631)
                     /locus_tag="MIV85_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBY2960245.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAMPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23757..25010)
                     /locus_tag="MIV85_000877"
     CDS             complement(23757..25010)
                     /locus_tag="MIV85_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2960246.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25061..26215)
                     /locus_tag="MIV85_000878"
     CDS             complement(25061..26215)
                     /locus_tag="MIV85_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBY2960247.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26775..27344)
                     /locus_tag="MIV85_000879"
     CDS             complement(26775..27344)
                     /locus_tag="MIV85_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBY2960248.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27547..27774
                     /locus_tag="MIV85_000880"
     CDS             27547..27774
                     /locus_tag="MIV85_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBY2960249.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(27993..28736)
                     /locus_tag="MIV85_000881"
     CDS             complement(27993..28736)
                     /locus_tag="MIV85_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBY2960250.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNATSQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28904..29776
                     /locus_tag="MIV85_000882"
     CDS             28904..29776
                     /locus_tag="MIV85_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBY2960251.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29776..30441
                     /locus_tag="MIV85_000883"
     CDS             29776..30441
                     /locus_tag="MIV85_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBY2960252.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30462..31319
                     /locus_tag="MIV85_000884"
     CDS             30462..31319
                     /locus_tag="MIV85_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2960253.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31475..34021)
                     /locus_tag="MIV85_000885"
     CDS             complement(31475..34021)
                     /locus_tag="MIV85_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBY2960254.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34021..34707)
                     /locus_tag="MIV85_000886"
     CDS             complement(34021..34707)
                     /locus_tag="MIV85_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960255.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34790..35779)
                     /locus_tag="MIV85_000887"
     CDS             complement(34790..35779)
                     /locus_tag="MIV85_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960256.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35766..36452)
                     /locus_tag="MIV85_000888"
     CDS             complement(35766..36452)
                     /locus_tag="MIV85_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960257.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36952..40158)
                     /gene="carB"
                     /locus_tag="MIV85_000889"
     CDS             complement(36952..40158)
                     /gene="carB"
                     /locus_tag="MIV85_000889"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBY2960258.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYSTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40351..41400)
                     /gene="carA"
                     /locus_tag="MIV85_000890"
     CDS             complement(40351..41400)
                     /gene="carA"
                     /locus_tag="MIV85_000890"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBY2960259.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(41657..44863)
                     /gene="carB"
                     /locus_tag="MIV85_000891"
     CDS             complement(41657..44863)
                     /gene="carB"
                     /locus_tag="MIV85_000891"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBY2960260.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(44916..45959)
                     /gene="carA"
                     /locus_tag="MIV85_000892"
     CDS             complement(44916..45959)
                     /gene="carA"
                     /locus_tag="MIV85_000892"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBY2960261.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(45985..46701)
                     /gene="pyrF"
                     /locus_tag="MIV85_000893"
     CDS             complement(45985..46701)
                     /gene="pyrF"
                     /locus_tag="MIV85_000893"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBY2960262.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(47077..47712)
                     /locus_tag="MIV85_000894"
     CDS             complement(47077..47712)
                     /locus_tag="MIV85_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBY2960263.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(47736..48650)
                     /locus_tag="MIV85_000895"
     CDS             complement(47736..48650)
                     /locus_tag="MIV85_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960264.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49251..50480
                     /locus_tag="MIV85_000896"
     CDS             49251..50480
                     /locus_tag="MIV85_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBY2960265.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWNIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(50685..53066)
                     /locus_tag="MIV85_000897"
     CDS             complement(50685..53066)
                     /locus_tag="MIV85_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBY2960266.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(53038..53763)
                     /locus_tag="MIV85_000898"
     CDS             complement(53038..53763)
                     /locus_tag="MIV85_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBY2960267.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKYVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(53753..54208)
                     /locus_tag="MIV85_000899"
     CDS             complement(53753..54208)
                     /locus_tag="MIV85_000899"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBY2960268.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(54490..55671)
                     /locus_tag="MIV85_000900"
     CDS             complement(54490..55671)
                     /locus_tag="MIV85_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBY2960269.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(55661..56353)
                     /locus_tag="MIV85_000901"
     CDS             complement(55661..56353)
                     /locus_tag="MIV85_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960270.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(56487..57203)
                     /locus_tag="MIV85_000902"
     CDS             complement(56487..57203)
                     /locus_tag="MIV85_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBY2960271.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            57328..58062
                     /locus_tag="MIV85_000903"
     CDS             57328..58062
                     /locus_tag="MIV85_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBY2960272.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(58347..59198)
                     /locus_tag="MIV85_000904"
     CDS             complement(58347..59198)
                     /locus_tag="MIV85_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBY2960273.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDSIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(59224..60162)
                     /locus_tag="MIV85_000905"
     CDS             complement(59224..60162)
                     /locus_tag="MIV85_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBY2960274.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(60265..60915)
                     /locus_tag="MIV85_000906"
     CDS             complement(60265..60915)
                     /locus_tag="MIV85_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBY2960275.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(61064..61252)
                     /locus_tag="MIV85_000907"
     CDS             complement(61064..61252)
                     /locus_tag="MIV85_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBY2960276.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(61359..62543)
                     /locus_tag="MIV85_000908"
     CDS             complement(61359..62543)
                     /locus_tag="MIV85_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBY2960277.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(62685..63602)
                     /locus_tag="MIV85_000909"
     CDS             complement(62685..63602)
                     /locus_tag="MIV85_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBY2960278.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(63624..64352)
                     /locus_tag="MIV85_000910"
     CDS             complement(63624..64352)
                     /locus_tag="MIV85_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2960279.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(64548..64748)
                     /locus_tag="MIV85_000911"
     CDS             complement(64548..64748)
                     /locus_tag="MIV85_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960280.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(64873..65253)
                     /locus_tag="MIV85_000912"
     CDS             complement(64873..65253)
                     /locus_tag="MIV85_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBY2960281.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(65526..66884)
                     /locus_tag="MIV85_000913"
     CDS             complement(65526..66884)
                     /locus_tag="MIV85_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2960282.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDGEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGLLRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDIRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            67332..67784
                     /locus_tag="MIV85_000914"
     CDS             67332..67784
                     /locus_tag="MIV85_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960283.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRIFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(67941..68558)
                     /locus_tag="MIV85_000915"
     CDS             complement(67941..68558)
                     /locus_tag="MIV85_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBY2960284.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
BASE COUNT        21638 a        12632 c         7441 g        27034 t
ORIGIN      
        1 tttcgtcaat actttttttg ttttttattt taaaaaaggt tataactttt gtttttttta
       61 ataaatataa ttaaaactaa tagatataac ccttgatatt acaaacaata catgcatata
      121 taattttacc tattttgcaa ttttattttc ataagaatat gaattagctc tcactctatc
      181 tgcccaaaca tttatactct taactttatt aacattagtt gtaccctcaa aaatatccat
      241 tgcatcctta caaaaatata tcataacatc aagaaccaaa aatccaacac aaaataaaca
      301 taaaaaatta attacttgaa acatcagaca ttcccccaat aattttttat atatagtatt
      361 ctcataaatt attcttttta ccttctcata aattattcta aatattttca taataaatta
      421 ctttcaatca tattttctaa atataaagtc tcaatcaaca aaaactaata tcaatttcta
      481 acgtttgttg gtaatttata aattaaatat ctaaaagaat ctttgaagca tataaaaagc
      541 attctacact gacattttaa ataaaattta gctatttatt gataatttaa tagctaaact
      601 ttatttaaaa cttagtagaa tgctaatatt tcttagtttt cttcttcttt atttggattg
      661 ttatcaatag gtttcatagt cgggaataat aatacatctc ttatagatgg agagttagtt
      721 aataacataa ttactctatc tatacctatt cctagtcctc ctgtaggagg tagacctacc
      781 tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt catcatcacc taattctctt
      841 tttcttaatt ggtctataaa tcttcctttt tggtcaatag ggtcattaag ttcagaaaat
      901 gcattagcta actcccactt attagcaaat gcctcaaatc tatcagttct tcttgggtct
      961 tcaacatttc tcttagataa tggagatact tcaactggat gatgagttat aaatgttggt
     1021 tggattaatt tatcttctcc aaattcttca aagaaagcat ttattacttc tcctcttctc
     1081 attccaggtt ttatctctat acctttttct ctagcaactt ctagtgcctc ttcatctgta
     1141 tttatagtag aaaaatctac accagaatat tctttaacac aatcttccat actcattctt
     1201 ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt taactatcat acttcctgta
     1261 gcaacttcag ccatatgtgc aataacattt tctgttattt ccatcatatc agtatagtct
     1321 gcatatgctt gatataattc tattgcagta tattcaggat tatgttttaa atccatacct
     1381 tcatttctaa acattcttcc catttcataa actttatcaa atccaccaac aataagtctt
     1441 tttaaataca attcattcgc tattcttaaa tacattggta tatgtaaagt attatgatta
     1501 gttataaatg gtctagcatt tgccccacct gctatagtat ttaatattgg agtctcaact
     1561 tctaaaaatc ctctatcatc taagtatgct cttaatgctt ttaatgcttt tgttctaatt
     1621 aaaaaagcat tttttacttc tggatttact attaagtcaa catatctttg tctatatctt
     1681 agttcttggt cttttaatcc atgatatttt tctggtaaaa cttgtaaaga tttacatagt
     1741 aatactacag atttagcctt tacagatatt tcaccttttt tagttttaaa gatttctcct
     1801 tcaattccaa ctatatctcc aatatcatat gttgaaaata cactatattc ttcctctcct
     1861 atagcatcta gtcttacata agattggatt cttccctctt ggtcttgaat atctataaag
     1921 ccagctttcc cttgtattct cttgctcatt atacgtcctg ctatttttgt agttttaccc
     1981 tcaagagaat caaagttatc ttttatatcc atagaataat gagttctatc atatctactt
     2041 tctttaaaag gatctctacc tgattcttgt aattttttta gtttatctct tcttacttga
     2101 agtacttcac taaggtcttc ttgaatttgc gcttcttcat tgctttgttg attatttttc
     2161 atttttttcc tccaaattat cttcttattt ctaatatttc aaacttagca actccatcag
     2221 gaacttgcac ttccacaact tctttcgcag ctctacctaa aagtgctttc cctacaggag
     2281 attcgtttga tattttacca tcatatgggt ctgcttctgt cgaaccaact atagtatatt
     2341 caacctcttc atcaaattct aaatccttaa ctttaactat tgatcctatt gtaacaacat
     2401 taaggtctat tttgctttca tctatgataa cagcttttct aaccatattt tctaatttta
     2461 aaattctttc ttcaacttgt gcttgttcct ttttagcttc atcatactca gcattttcag
     2521 ataaatcacc aaaagatata gcaactttta ttctctctgc aacttctttt ctctttacaa
     2581 cctttaagtt ttctaattct tcttctaatt tatcatatcc ctcttgtgtc aataaaaact
     2641 ctttattttc ttccattata aatacaactc cttcacaaat ttcttaggaa ttttcctaat
     2701 tatattttaa aaattttata atcttttttt aatttatgcg ctatattata agtcactatt
     2761 atttttatgt caaggagtct tccatatagt actccaattt cgacacaact tcttgatagt
     2821 cttctatttt gttaatttca tcccttaatt ttgcagagtt tctaagtcct tttaaatacc
     2881 aagcgatgtg ttttctcatt tcccttacag ctacatactc tccatgttct tctactgcaa
     2941 gttttaaatg cttaatggca gtacttattt tttcgttaag agttggctct ggcaaaatct
     3001 cgcctgtatt catataatgg tttattcttt taaatatcca agggttacct tgagcacccc
     3061 tacctatcat tatagcatca caaccagttt tgtctaacat atttattgaa tcttctattg
     3121 taaatacatc accatttcct ataacaggta tactcaaatt tttcttaatc tctgcaatta
     3181 tatcccagtc tgctttgcct gtataaaact gttctctagt tcttccatgt attgctaaag
     3241 cacttattcc acaatcctct gctatctttg ctatttcaac agcatttaca ctattatcat
     3301 cccagccttt tcgaatcttt aaagtcactg gcttttttga gttcttcact actgccctca
     3361 atacctcttc tgcaagctta ggatttttca taagtgctga accatctcca tttttaacta
     3421 cttttggagc tggacacccc atatttatat cgagaatctc atttgaataa tcattcatta
     3481 tctctgctgc tcttcccata aactctggtt ctgaaccgaa tatctgaact gctacaggat
     3541 gttcttcctc ttctatctta agcatttttt tagtattttc atcatcatag caaagtgcct
     3601 taccatttat catttctgta tataaaagcc cacatccttg ttctttacaa attaatctaa
     3661 atggaaggtc tgttacacct gccataggtg atagaaaaac tttatttttc aattctaaat
     3721 ttcctatttt cattgttttt ctcctatttt tgcctttatt ttgtgattta actttaaatt
     3781 cttatttcct cattataata taccacatat agctagaaat ctatcataaa aagggaattg
     3841 gatatataac ccaattccct gtatattaat tattcttggt ttttttcata tattattctc
     3901 aatccttcta gtgttaaaaa accatctaca taatctatac ttttcgtctc tgaagcaatc
     3961 agtttagcta acccacctgt agctataacc ttaacatcat cacaattcaa ttctttcttc
     4021 atcatactta ttattttgtc aactaaacca acatatccat aaattattcc agattgcatg
     4081 gctgatacag tactcttaca aatagtcata cctggcttag ctaattctac tctaggtaat
     4141 ttagacgcac tttgaaataa cgcctcacta gatattttta ttcctggtgc tattgttcca
     4201 cccaaatatt cacctttttc agagatagca caaaatgtag ttgctgttcc aaaatcaaca
     4261 agtatacttg gtgctccata cttttctatc cctgctacag cattaactat tctatctgcc
     4321 ccaacttgtt ttggattatc atattttata tttagacctg tttttatgcc tggacctact
     4381 attaatggct gttttttaca gtactttata caaaagtttt caagagaatg cataacattc
     4441 ggaactacag atgatattat aacatcatca atatcactta tattcacatt atcataatca
     4501 aataggttac ttattaggat tccatattca tcagacgttt tttctctatc tgttttaatt
     4561 ctccagtaat taactaattt gtcaccttta tatataccta aaaccatatt agtatttcca
     4621 acatcaaata ctagaagcat atgtcattaa ccttctttct attttttgct tttcttaagt
     4681 acagtggcaa cagcagctac tactaaagcc cctactattg cttctggcac cccatttgct
     4741 gcggcaagag ccattattac ttttcctgct gaaccacttt tacccattgc atgaagatac
     4801 ttgtcagcat ataagacata tatcattcct aaaactccag ctgtatttaa cagagaacct
     4861 attgcccctg taattaaacc tgatatgtat accttatttg tagccttaat tattaactga
     4921 tatacataat aagctaatac acctatcata actcttggta atattgaaac taatggattt
     4981 ataaaaacaa aagatgttac tgttgggttt gttatagcat ttaagagact tgatatccca
     5041 aatataaatc ctattgctgc cccaactatt ggtccttcca taatagctcc aataataact
     5101 ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa taaatcccaa tggagtcata
     5161 gatagcataa tagaaatagc tgatagtact cctattatag tcatctttct tacatttact
     5221 tttcttactg atgcacttgt gttcatcata aaaaatacac ctccgttcca gctcattaag
     5281 atgccggact acttaatttt ttaatttttt tcgttttttt cttataacta tgagtcaagc
     5341 taccattgta ggatgcccgc tctaacaaga ataattttat caagatgagt tgccattgtc
     5401 aacaatttga caagaaaaat atgctaattt catcatattt ctcgtttttt tactatatct
     5461 ttatatgcca ttatattttc tacactatcc gcttttttta ctgcatttat tatacttttt
     5521 tccacaacct ctacagccaa tgaacctact aatgttatat ctgcttctat ttctcctgtt
     5581 gatattgtga atattgtatc tccatcatga ggtgtatgga taggaaaaat agacttagca
     5641 tatccatcat gtcccatttg agatatcttt ttacatccag ctttggttaa cttagcattt
     5701 gttgcaatta tcccaattgt agtattatct acactaaatc cacctttact ttcaccttgt
     5761 ttcattaatt tatatgtatc aattgtttct gtctttttat catttaaagc accagctata
     5821 accttaccat tttcataaac atctccaaga gcatttacag caattaatgc agatacaatt
     5881 agaccattat ctaattttat agaatagcta cctattccgc ctttcatagc atattcctga
     5941 cctcttatct ttccaacagt ggctccacaa cctgctccat aatttccttg atttaaaata
     6001 tcagtatttg caacttcaca agctctataa cccatcttta aatctggtct acatttaaag
     6061 ctccctactc ctaaatcaaa taaaactgct cctacaacta taggcacttt acctacacct
     6121 acatcaaatc caattccttt ttcttctaag tatctactta caccacaagt ggattcaaga
     6181 ccatatgcag aacctccagc caaaactact gcatgaactt tttgaaccat atttacaggg
     6241 tctaataaat cggtttctct agtacctgga gcagagcccc ttacatcaac accgcaagta
     6301 gctccttctt cacatattac tactgtgcac ccagtaagac catttctatc ctcaacctgc
     6361 ccaaccttta agccttctat atccaaaata ttattataca tatccttttt ctcctcttat
     6421 agaaacttca cctgaaataa tttcttttat acttccatca cttctttgaa ctaataaatt
     6481 tccctcttca tttatgtcta aacatttcac tagttctcta ttatctcctt ttaatacata
     6541 tatattttta tctataattg cagaataatc tctacatatt tttaaggttt tttctttgga
     6601 attatttaca gtataatcta aatataattt ttcaaattca gtcaatacat tcctaacaat
     6661 atctactctg gataacatat acccttcttt atacaatgat gtggctttgt cagctatttc
     6721 ttgttcaaaa tccattattt taacatttat tccaattcca agaacaacat aatttgttct
     6781 ttcaatttca gcagataact ctgttaatat accacatatt ttttttccat ttaaaataac
     6841 atcatttggc cattttatta atgtatttgc tcctagattg tttaaagctt tcgttacact
     6901 tgctcctgct attaaagtta taaatggggc tttgaatggt tccatatctg gttttaatat
     6961 aatactcatc cagattcctt catgaggttt tgaatcccat cttcttccca atcgtccttt
     7021 ccccatatct tgatgttcac ttaaaatcac agtcccatct acactattta tagctatcct
     7081 tttagcatgt tcatttgttg aatctatagt gtcaagatgt tcaatatttt ttccaataaa
     7141 ctctgtatct aatttatagt aaatattctg tgggcttaat aaatcagttg gattttccgc
     7201 taatcgatac ccttttttat ttacagattc tatattatat ccctcttctt ttaaggcttt
     7261 catatgtttc catatagctg cacgtgacac ccctaattgt tttgataatt cttctcctga
     7321 aataaattca gatttattat ttaatataat ctctattatt ttatctctca tatttcacct
     7381 ctaatatgac ataatttcat gacttatttt cttctaataa ataattatac attattaata
     7441 tacttttaat actattaatt ttaaatttcc tttttaatta ttataatggt tgttttatat
     7501 tttatattga tgatttatat aattttacat tttatttaaa taattttaaa ataataaaaa
     7561 aactgaaagt atcaattaaa ttaatacatg caaatataat ttgcttatta atttaatatt
     7621 atactttcag ttttagtatt taatccacat cagataataa tcttaaaatg accaaggtct
     7681 taaaactatt tatctttatc agatttatct tctaaatttt tatttatatc aataacattg
     7741 tttctttctt cttcatcttt ttctaatttt atagttaatt gttcttcaac ttctttagaa
     7801 gaattttcct ctgtaactgc attttcaatt tcattcagag gtaactcttt attaaatgct
     7861 tttacaaatt gttctgcatc taaagtttca tatataagta aagcttgtgc tacatactct
     7921 aatctatcca tattttcttg taatatactt cttgtcttat catatgcacc atcaactata
     7981 cgctttgttt cttggtctat ctcaaaagca acttcttcag aataatttct cttacttgaa
     8041 aaactattac ctaggaatac ttcatcatca ctgtcaaatg acattggacc aagtttagaa
     8101 ctcattccat actttgttac catacttctt gcagtagctg taactctttc taagtcattt
     8161 gaagcacctg tagatacatc cttaagtact agctcttctg ctactctacc accaagtaaa
     8221 actacaatat tttctttcat ttcatttttt gtagcataga acttatcttc aacaggaagt
     8281 tgcattgtaa accctccagc tcttcctctt ggaactattg taacttgatg aacaggactt
     8341 acttcttcaa gtacatgggc acaaactgca tgccctcctt catggtatgc tgtaagtctt
     8401 ctttctttct cacttattac tttcgatttt ttagccacac ctgctataac ctttgttata
     8461 gcttcttcta tagtttccat cttaattttc ttttctcttt ttctagctgt taatattgca
     8521 gcctcattca ttaagttctc tatatcagca ggagtaaatc ctggtgttct tctagccaag
     8581 acatccattt ttacatcatc acttaatggt ttatttcttg agtgaacttt aaatatagcc
     8641 tctctacctt ttacatctgg tgtaccaaca acaacttgtc tgtcaaatct tcctggtcta
     8701 agtaaagctg ggtcaagtat atctggtcta tttgtagctg ccatgattat tataccttga
     8761 tttaccccaa atccatccat ttcaactaga agttgattaa gagtttgctc tctttcatca
     8821 tgacctccac caagacctgc acctcttttt ctaccaactg catcaatttc atctatgaat
     8881 atgatagctg gagcactttt cttagcctgt tcaaataaat ctcttactct tgaagcacca
     8941 accccaacaa acatctcaac gaaatcagaa ccacttatac tgaaaaaggg aactcctgct
     9001 tctcctgcaa ctgctcttga tagatatgtt ttaccagttc caggaggtcc taccataagc
     9061 attccttttg gtattcttgc acccaattca atatatttct taggattctt taagaaatct
     9121 actacctcct gcaaatcttc tttttcctca tctagtccag ctacatcttt aaatgtaact
     9181 ctagtttttt catcatcttt atgaacctta gcttttgatt tgccaaaact cataaccttt
     9241 ccgcctccac cttgagactg attcataaac acgaaccaaa taatcaccat gaagaatatt
     9301 aacagtaatg taggcaacat ttcgacaaac caaggtgtag atggcttagc ttcaccacca
     9361 aaagttagtt tcccagcctt agcttggtct aacacctcat ctgcaagttt atttcccatc
     9421 acttctgttg gaacatatga cttaaacttt gtatttgtat cttttatagt accttctaca
     9481 gaagtttgat ttacaaagta taatcttgat atattctcat ctgttaattc tctatatact
     9541 tcagagaatt ttaaatcttt tattttttct gtaggcttac ctgagaattg aactatacct
     9601 actataatta taaaaacaag tagataaaaa cctgcccctt ttagcaactt attcaatata
     9661 gaagccctcc tttcatacat tgctttgccc tataatttgt taaaattaat ttttaatact
     9721 tcttttgtgt tttcatcaat tttataattt tcactgattt tataatctcc aacacatatt
     9781 attccttcac tatctgtgat tataggaatt ttacatcttt cttctcttgg gatttttaaa
     9841 tctatgaata aatctttcac ttttttactt cccatagcaa gctttatctt atcaccttgc
     9901 cttctgcttc ttattactat accccctttt accttattaa aatcaaaccc tttagatgaa
     9961 ttgtctaatt tcatactctt atacctatct atgctcatta cttgggtctc aataatttgt
    10021 tttaattctt ttattttaat aaacccatta ctaggtacat tgtaataaaa ttcaatttcc
    10081 tcattaacaa tttcctcatt cgttaatatt atactgtctt tttttctata aacaaatata
    10141 tttcttggaa gagttaacat tttatttact tttgaattat cttctaaaga cattatatct
    10201 tctatatgtc tttggtcaac aaaattagta tctcctagta tatgttttat ggaatttcta
    10261 agaactctaa ctttgatagc atcatgtaag caaacaaaat cgtctaaatt tatctctaca
    10321 aagccttttt cttttatatt tgaaacttct ctaaatttag cttctgcctc tttctcaata
    10381 taatcgttat cactttttaa actattgctc atcctcacta tagattctat tacatttgaa
    10441 ttaaaattat ccttcatata tggtaaaagg tctaacctta tcttatttct agtgtatata
    10501 ttttctaaat ttgttttatc tatcctcgga tttaaattat aagcttcaca atactcctct
    10561 atctcatttc tttccacgtc taatatgggt ctaattatgc aattatctct aatataatca
    10621 attcccttta agccttttaa acctgttcct ctcatgatac gcatcataac cgtttcggct
    10681 tggtcattga gattatgacc tattgctatt ttattggctt taatcttatc cttaatttca
    10741 taaaacattt catatcttag cttccttgct ccttcttcta atgataatcc ctcattttca
    10801 caatattttg gtacattaat agactttaca aagaatataa ttcccatatc ctcacaaagt
    10861 ttagatacat ataatgcatc tttttgagct tctatccctc ttatttgatg gtttaaatgt
    10921 gctgcatata tttctatatt aaaatctttt tttaatctat ttagtacatg caataaacaa
    10981 actgaatcag gtcctccaga aagacctaaa actattttat cgcctttttg tattaaatta
    11041 tgtttattta tagtacttag taccttatca aatatcatat ttatccctct tacacttagt
    11101 tttattcact tttaagtata ctttctataa aaaaacgcta aacccttgta tcaattttaa
    11161 gaaattaaag tttaatataa atataataat accaaataaa ttaaataaaa ggtagttttt
    11221 tcactacctt tataaaattt ctggaaaata gccatagtta ttatttagta cctatgtata
    11281 tatctatttt attcctacct aaaaataaat cttgtacctt tatattatag tctattttca
    11341 attttatgtg ttccccttct tgtatattta tatctaattc tcttgtatca atatcaatta
    11401 ataaagtacc ttgtggggtc acatactttg tagtactact ttctccacat ttaaacagca
    11461 ttgttgagtt aatagcacca aactttttga tactaacttg atttttaagt atctttatag
    11521 tattagttat ttctatatct tcttcttttt ccttgtaaat aacatatatt ccatcatttt
    11581 tataaaaaat tttaccaaag gcagtcatct ctatggtgtc catatttcct ttttcatcat
    11641 attgtctagt atttatactt atttttacac tcaacgattt ttcctccata gattcttcat
    11701 ataaactagt atttttgtat ttctactttt tgaatcttat caattttttt ctttaagaac
    11761 tctcttgcta tatctgaaaa tttttcaggt atatctgata cataatattg ataagttcca
    11821 tgaatttctg tattgtttat aatattttgc acctctaaaa tcttttttaa atcctttgca
    11881 gtctctttag ctggattaac aagttttata tgctctccaa cttcttcacc tattgttctc
    11941 tttaaaatag gataatgagt acatcctaac actaaagaat ctatattttt ttctttcaat
    12001 tcttgtaaat atatctttgc tgtcagttta gccacttctg tatttgccca tccttcttca
    12061 acaataggca caaataaagg acatgcttta ttaacaattt ctatactctc atctatttta
    12121 gatatttcca agttgtatgc ttttgaactt atagttcctt cagttcctat tattcctaca
    12181 attttgtttt ttgtagaact tacagctgtt ctagctcctg cttctataac tccaattatc
    12241 ggtatatcat atttttcttg agcttctttt aagcttcttg cagtagcagt gttacatgct
    12301 ataactatag cttttacacc ttttgttttt aaaaagttta tagcttgaaa agtatattta
    12361 attatagttt ctttggatct tgaaccatat ggtattctgg cagtatctcc aaagtatatt
    12421 atatcctcat ttggtaatat cttcattatc tcttttagaa ctgttaatcc acctaatccc
    12481 gaatcaaaaa ctcctattgg tttattgttc atctttatac aacacctact ttacattttt
    12541 gtgtttaaca acaacttatt tatcgctaaa atttatattt atattcataa ttaatatatt
    12601 attacctaaa tgattattat agtttatttt acacaaaaaa taaaggagct atcttaaatt
    12661 agaaaataat ttctacaaaa agacaactcc tttcactact taaaaattta aatttatttt
    12721 gcaaacacat gatttcctat tctcatataa ggattcaatc tatttatcca tttgcaagtg
    12781 gctatttctg gattccaaaa atatactgct ttattagttg ggtcagttcc ataaagagct
    12841 tcctgagctg ctttacgtgc tgagtctgtt ggtgccatct ttattgaacc atcaagcaca
    12901 actgagaaag catttttttg atatatgact tcttctattg tgtctggaaa tctagggtcc
    12961 aatactctat ttattactac agctgctaca gcaacctgtc cctcatagct ttctcctcta
    13021 gcttctcctg caaccaactt agataataac atcaagtcat tatcagataa atttattact
    13081 tctttctttg ctatattttt ttcttgtttg tttactttct taatattttc tgttggttca
    13141 tatgcaaata cctctttaat aggcataaat ataaaagtca aagctaatag tgtagccatc
    13201 agtttactcc acctgtccat gattaaaacc actccttaca ttcttatttt taaaattttt
    13261 tctctaaatc cttgactact tcaagtactt taaatttaat ttttactcta cttgtttttt
    13321 ttggtgtatc ttgttttatt aacttatatt ctttatcagt taaaacttcc ttcaacttat
    13381 catctgtaga tttatctatc actccattag attcatcaac aaaacatagt ggagggaaca
    13441 taacacacca ccagtttttt ccttcacctt tcccaatgat aatctttaat gctttatatt
    13501 caccagctgg aagaactata ttagaatatt gtttagtagg gaaattgcta tattgtatac
    13561 ctacctttac actgtaatta tatccatttt taagaataat atttttactt atttcttcca
    13621 aactactata ttcctttttt ataatagctt cactttcttt tatacttttt gaattttgaa
    13681 gctttggctg taaatatttt attacttcat ctctaacttt tagtttaagt tcttggtctt
    13741 catctgtatt gctgtttgct ataacatgaa atcttattaa tttatcttta taatcttttg
    13801 atatattgtc tacttttttt acctcaccat ttattactat tgtcattatt gatatgactg
    13861 atataagact taatattaat agtcccaatc taatcttaat ttttctcatt gaaaattccc
    13921 cctcaagata aatttatatc atcaattatg tccaattaaa tttaatttat tcataatatt
    13981 ttttaatact aataaaaaaa gctatcttaa aatgattaca atcattttaa aatagctttt
    14041 taaaccttat attttataag tctttactaa tcatagcctt atctatcata aactgctctg
    14101 ctttttctat atgctctgta gcatacttct tggatagctc actatcacct ttaattatag
    14161 catcaagtaa atatttatgc tcttcaacaa tattatgtga tgtatcataa gcagacatat
    14221 aggtaactct aaatctatat acttgttccc acaatgagtt tattaattgg attaattttt
    14281 tattattagt tgctttaaat atacattcat gaaattctac atcaagtttt aataacgcat
    14341 ctacatcgga ttccaaagtg ctttttttaa attcttctga tatatcttta agctttttaa
    14401 tatcttcatc actaattctt tcagcggcaa gatatgctgc taagccttct aggcttgctc
    14461 ttacttctaa tacatccata atatccttta atgacatatt tgccacatac gcaccttttc
    14521 taggcaacat aacgactaaa ccttctaatt caagctttct tattgcctct ctcactggag
    14581 tcctacttac tcctaattgt tctgctagtt gcacttccat tagcctttga ccaggcttta
    14641 attttccttc taagattgct tctcttaaat tctcaaagac tacatctctt aatggcttgt
    14701 aattatccaa gttcagttta gttaaattct ccacaaattt caaccccttt ttgactgcta
    14761 ttaacaacat acacctgttt atattttttt aataattctt tttttccaat tagagcatct
    14821 tctttatttt taaatagtcc aaaaactgta ggaccacttc cactcatcat agaacctaaa
    14881 gcattatttt tcatcattac ttgttttata tcacttattt ctttgtgttt acctatagta
    14941 acattttcaa gaatatttac catgctttct gatacagctt ttatatcttc agattttaaa
    15001 cactctatca aatatttatt atttggtctt tttttaatat tattcaaatc taatccttga
    15061 taaacttctt tagtagaaac gaataagtct ggtttgcata tcaatatatt tgtatcacat
    15121 ggtaaacctt tgatgtttgt tagcttttct ccaatacctt gagctaaggc aggtcttcct
    15181 gatatacaaa aaggaacatc tgcgcccaaa ttaagtccta tttcttttaa ttcatcttca
    15241 gataatctaa gttcccatag gtgatttaaa cctactaata ctgcggctgc attagaactt
    15301 cctccagcca tccctgctgc tacaggaata tttttttcta tgaatatttc tacacctttt
    15361 tttatataaa atttattttt aagtattttg gcagctttat aaacaatatt atcttcatct
    15421 aaaggaatat ctaaactagt gctttttacc tttatttcat cttcgtctaa ttcttttatc
    15481 tttactatat cgtataaatc tatcgtttgc attatcattt caacaaaatg ataaccgtct
    15541 tgcctttttc ccaagacatc aatggataaa tttatttttg ctctactctt tagtcttata
    15601 aaatccattc tatcctcctt gtttaaagaa taatgcatca ctaacaataa tattatacta
    15661 caaaaaataa aataataggg tattataata ccctattata cttaattact ttaaattttt
    15721 taatattaat ctactaatac gacttttttt tctaaaataa gacacttacc aggcttaatt
    15781 ggttcatcaa gttttatatc attaagttct gcaatttcat tttctgttgt attgtatttt
    15841 tttgctatat tccagaaagt atctccttct ttgcatatat atacgattat gctaggagct
    15901 ttagataaat catatacacc ttggtcttct cccttgataa taaaattttc tgctttctta
    15961 tctaatgctt cagtaaatct cttaattttg ataatcaagt ctatctggtc cctattcaaa
    16021 tcaacttcga ctttatcaat acatgctgta ttaaacacag atgctgtatc agttagatta
    16081 tccatttcta tatcatgttc aaatggaatt tcctcactaa ttttataaac caattttaaa
    16141 ccttcaactg ggacaaataa aatttcaact tttatgattc cttgtataat gcttttattt
    16201 ccttcaatat aactattttc tatagacatg gttggacaaa cgcttacaat atcttttatt
    16261 tgtatatcat cattatcatt tcttatgcct tctctaacca taaatgtttc ttcactacgt
    16321 cttaaagtct tatttaattg aataggtttg tggtcaaatt ttattatctt ttgaggcgaa
    16381 tatgcatctt gtaatacttc tcttgtaact tcatctgtaa cttttacctt acaacaagcc
    16441 atacaatcta tttctaaaag acctgtgttg ctttcactat tttgcttgaa aatatgatta
    16501 aaatctgaca tagacaacaa tacttcttca gtcataccat cactaactcc agggacttct
    16561 acaaattgag taaactcaat acctactcta tccaactcta caagttcacc ctcatatgta
    16621 caagctaacg gatttatttc taatactcca ccaataataa ctttattgtc agtcactcta
    16681 ctttctttta ctttaacaca tggatttaaa cttattatag attgaatttc ctctgtgttt
    16741 attgttatag tatctcttat agaactttct gctttttcta ttccaactat atcttgaaaa
    16801 caaatttcct ttctgtgctt ttgtatgcct tccacttgcg ccacatcttt tacaatgtct
    16861 aacctttgct tttcaaacaa acttcccctt atattcataa gagctcctac tttaatcttt
    16921 ctctcattca ttatagtaca atccatatgc tctacttctg aaaataacat gtattccata
    16981 tcttgaacaa cattgtcttt ttctattact tcgtttatat ctacttttcc gtctacatta
    17041 gaaatagtat ttttatcatc tgcaatatag attacattat aattaaaact acctctgcaa
    17101 agtatcttcc catctgccat ttcaattttt ttaagtgata tgtatccttc tgtttttaca
    17161 atttcatata catctaattt tttgtctggt acaactgcct ccgcttcaat gaatgtttga
    17221 aattttccaa agtctattct attgtcaact ttaattacat ctttaattaa ttccatagtc
    17281 tacctcctta agtattataa aaatatcaca ctatatttat atttaaggag caaaaaaaaa
    17341 attacaccta tttttaaata ggtataattt taacttattt gtaatttatc ttgatctcta
    17401 aaaacttgca actttacatt agatgttaat aaatctgagt aactataaga tactctagga
    17461 tatccattac tttcatcatc taactttata acaaacacgc ttggataaac tttttctagt
    17521 ataccctctt ttgtaataat ctgctttctt cctttattag ctttcaacaa tattttcttt
    17581 cctatatgtc tctctaagct tactcttatc ttatctagag tttgaacagt agccacaata
    17641 tcaccttctt taacgtttat atgtttacat aatatcacat ataaacattt ttgtcaaatg
    17701 tttaaactaa ttattttata tattttttgc aaaaatgtca atactatttt tgaagatata
    17761 cagtataatt atgttaattt ttgctaatgt aatattgttt ttggcattgc ccatctaaat
    17821 tttcctctgg tttcagaacc accaattccc ttaacacctg taatagtctg ctctataacc
    17881 tcatcaatag gaactactac atcaattctt gaacaagcaa ttttctccac tataaaaaca
    17941 gggtctaatg catgtatcat tatccttcca ggcgaacttg catagtttgc tcctgcactt
    18001 attatttttt cataatttga ttggcatgct cctgcgaata tgacaagatt atccaaattt
    18061 ggttgccatt tacgtgcttc ttttactgtt ttaacaaaat ttgaagagtt tctatagtta
    18121 ctcatatctt ctatatctcc tctttttatt gtcattgcat catgacctgt tattactagt
    18181 atatccggat tatatttttc tagtagtgct cttacttctt tatactgatt ttgctctgaa
    18241 acagctacac ctactgcagg tattccaagt tgagcatata catccaagca aatttttaaa
    18301 tattctttat ctccatctat ctgtagtact tttccaggca ttccatatgt gttaggattt
    18361 aattgaagtt ttggaactgc tctagtcatt cttttttgtc tttctttagc ttttcttact
    18421 gacttatata ataaattttc tacattttta tctattaata tatcttttat atcaggtgct
    18481 tttactaatt ctaggtcatc aatataagca tctgctatta ctctaaatgc aattcccttt
    18541 agtatagcta ttttctcatt attttcatct acaccaaaag agactatttt aaatactata
    18601 tctttgttat gtgactttct agctacaatg tctcctacct tcatagttaa acctccaata
    18661 aatttttatc ttagtttata ctatgttcga tataaaactt tgtttcctaa tgtcaaaaaa
    18721 acatttctta taatacttct tttatcactc ttaaagcatt tttatagtat atcttttcta
    18781 tatcatcttc actaaaccct tcttttttta gaggttcata cagtttaccc atctgagata
    18841 tatcttcaat ctcaactttt gaatctattc catcaaaatc tgaccctaga gatacaacat
    18901 ctattcctcc aacatttaca atatgtttta tgtgtctaac catatcttca agtttacttt
    18961 cacttttatc acttaaaaat aagtggaaga agtttatacc tgtaactcca cctttatttg
    19021 ctaatacttt aatcatatca tcagttaaat ttctagaatg attcatcatt gctcttgaat
    19081 tagaatgtgt agcaattatt ggtttagaag aaatctttgc aatttcataa aatccaccat
    19141 ctgaaatatg agaaacatca accaacattc ccaattcatt catcttatgt accacttctc
    19201 ttccaaaatc agtaagccct ttttctctat attctacttt attatgagga aagctcaatt
    19261 cattcacatg attccaactt attgtcatca ttctaacccc taagtcgtaa aatttcttta
    19321 aattttctaa tttaccttca agtactgcac cttcctcaat agataaaaga gctgtaagtt
    19381 taccttctga ttggtttttc ataatttctt catagttagt agctaaagct atttcatcac
    19441 tatttttttt catttcctca tgaaatttat ttgccatact catgcaataa tcaaaaggat
    19501 gttttacttc ttcagtatca acaaaaagag caaatgtttg agctaatgaa tccccctttt
    19561 tcaatctgtc tatatcaaca gaatatttat tagacttaag ttcacttgtt tctacatttt
    19621 ccattaattt tgctatagta tcacaatgta aatcaataaa tttcatattt ataccccctg
    19681 tatattttat atttatatct aaaaatagaa atagttgtcc ttatagacaa ctattgacaa
    19741 ctatttttta atattctttt taatattact taatcttatt cttcttttaa gttaggtatt
    19801 acttttttaa cttcttcaat ttgatgccat gttttatcta tattattttc actaatatat
    19861 ttttttaaat cagttaaaga tgtaaaatct ttaactgata aattgtcatc atcatctgca
    19921 aatcttaaaa taaacatgag actcccttac tttccacaac atttcttata tttttttccg
    19981 cttccacatg ggcatgaatc atttcttcct atttttgctt ctttaactat tgttttagac
    20041 ttcttataag cctttattat ttcttttctt tggtctgctg gtagtatatc ttcccaacct
    20101 tgtaaattat atagccaatg agcctcaaca gttaccatat tgttatataa tttttcccaa
    20161 tctattttta tagaaacttc tttatcagct tctacttctt ctaaaactat atcttctttt
    20221 aagctttcac ttattccatc tatgaatccc atgaaaaatt cattagtagt tccaaatttt
    20281 tcagccaatt cacttacttt accttcaaca acatccattt tattatttaa tatttcattg
    20341 tatattccag cttcaacttt caaatattct tcccagaatt ttacttctgc ttcttgactt
    20401 tcatgattat cacttaaatt tctccattca gtatataaac tcatactttt tcctcctaag
    20461 tatacctata tttttatagt ttttatagta taaaatcttt tagttagatt ggaagtttct
    20521 tctttttgat tataccatat tctatttaaa gttaactctt atattatatc ataattaaac
    20581 aattctttta atacttttat agcatactct tggtttataa aataagggct tgtcgcaatt
    20641 gttattactt tggctttttt aattaagttt tttatcttgt aaaatttgag ttcaaatggt
    20701 atatagtcca tatcacttga aaatatatcc aaatctatgt caagaacaaa ctctgattct
    20761 acttctaaat caaatccata tagactatct attattatta attctgaaaa tatgttatat
    20821 tttaaagcag gttttataaa acttcccaca tttaaaactt catttgtata tctaaataca
    20881 tcttttagat tatttacatc tacatcatag ttctcaggtt ctctagtatc cttatgttgg
    20941 tctacatgca ctaacttgca tccttttgta aactcaccct ttaacaaaga ctttgcccaa
    21001 aaataaaatg catggttatg attgtcaaac acatatatct ttttatttcc caggacatat
    21061 tcgaccatat tctccaatcc ttttgctttt atttccttat tttcatctac ttcattaaat
    21121 actacctcat tgcctaacct tacatcattt aatgtaccat ttataagttt tggaacgtat
    21181 atgctcttat tttctctttt atcatatgaa aatacattat ttcctactgg tttttctata
    21241 taaaatccac tatattcata attttccata aaactttatt tcctccattg ttatataaat
    21301 atataagtta taattttaaa aattaaaatg cacttattgt aaatcatatc atctattata
    21361 gaaaacatct tatataacta aatataatat cttctctcaa tatgtattat acaataagtg
    21421 taaaatatat ttatataaaa tatactacat tcctataaca aaaccatcag cttcaattgg
    21481 aagataacta actcttctat tcaactccac ctttccaaaa aatactaccc aatatggtct
    21541 aaaaatactt tcaattttaa ctatttcaat ctctgggatt cctcccataa acctatgagt
    21601 taatctcata gccattttat ttgcctttgc ttttactctt cgttcgtcct tatcactata
    21661 ctgcacaata ttacaatcca cattttttac aacttcatat gtaggaaaat cttgtactat
    21721 actaccagaa cctgtagaac cattcactaa aatttttaat tcatttatat cattagaata
    21781 tctcctattc ttgaaaatgg atttcgtttt gtgaatttta agtgtgataa ttttaaactc
    21841 tatataatga agtctaactt catgagcata tttgttcttt aatattagct tactaaataa
    21901 agaatttttt ccacttttag ctatctctat agcttcttct tttgtaattc ttataggtaa
    21961 cgctcttata tccataaaat cattctcttt cttatttttt tcttgtcatt tttaaaactc
    22021 tatatatata atcaaaaaat attacaatta caactgacat aactccatat ggaattattt
    22081 ttccaactat aatatcattt ctagtcaata taccataaaa tataaatcct gttattaaaa
    22141 agtacaataa tactagaaaa ccgtctattc caagccattt tatttctaaa tcttttttta
    22201 ccttagacac taatttagac atagcagttt ctccttttat agattatttt gtgtatttaa
    22261 attttcacct attctattac caatcatcca tgcaataaat gaaaaaggca tagctatcac
    22321 aagaggctct aactcaaagc tctgaactgg aaatatttta aaataaccaa aagtcactcc
    22381 accaacaatc attcctaaaa taccacccat agatgttctt cttccatttc caagaagccc
    22441 acctactata ggtacaaatg ccgaacccat ccaaatactt cctacaaata tacatgcatc
    22501 atatacattt tcaaatctaa atgctacgct aagccccata actgctgcta aacatacacc
    22561 tattctagta aactttacta attgtttctg agataactct ttttttgtaa ttcttccata
    22621 tatatcattt gctaatgtag ccccagctgc tagataatag ctatccaatg ttgatattat
    22681 agaacctaaa attcctatta taaatattac tcttattcct tgtggtaatg tatctaaaac
    22741 taaagttata tatccagcag ctggagccat ttctggataa gtagctctta ctataagtcc
    22801 tgtcatagtt aacaccatgt caaaacatat ccatagtgaa aaacaggtta ataaggctct
    22861 tcttccaacc ttaggagaat ctgctgctga aaatctttga taaaaagttg ggtctgaata
    22921 agctccaaaa gaatatacaa ttaacatcaa tgctttcata gctgacatac cctttgtagg
    22981 gtgcataagc tgtggtgcat ctttgagtgc ttctgtaaga ccttgaaacc ctcctatttg
    23041 ttcaaattga cctggcataa ccatagttaa accaaatacc atacaaaaaa acaataccat
    23101 atctgtaatg gcaactccca taagcccacc aagtactgta agtacaacga ctactcctac
    23161 cattattaat cctattaatt ctttatctat tttccatgct acgttaccta tagttcccat
    23221 agcagttatt tctccaagtt gtgcacaata tataaacatc aaaattgccc caattatagc
    23281 aacatgcttg ccataaaaac tttccagtaa atcaggaact gttatattgg ttcttatatg
    23341 aatccttgga ccaacccaca atgctaaagg cattctccca atatgtgcag ctattgacca
    23401 aactgcccat gcagatattc catatatagc cgcatactct acactaccta ctgtaccaac
    23461 tcctccatac catgatgcaa ccaaagttcc tactattaag gaccatggta aacttcgatt
    23521 tcctaggtaa taactttcca tatcttttac atttctagaa aaataataac ctattcctaa
    23581 taatataaat gcaaatataa ctataatccc attttcccaa aatgttaaca tatctaatct
    23641 ccacattctt atattttaat ttttaacttt aatatctaaa tatgaacaac tctacccatt
    23701 tccataaaaa taggtagagt tatataataa ttataagtat ttaagtaatc ttgttattaa
    23761 gcaattttat tgtttaaacc tttattttct cttttattta ttttatttaa agcataagta
    23821 gcaaatatcc ctataactgc acatactaca gataaaataa atatatatgt atatcctgtt
    23881 tgtccatatt tatctaacca attacctgca atagtgtaat aaaacgcatc tggagaaaat
    23941 cctataaatg aagcaaatcc aactactgct cctgtagttt ctaaagatat attagactct
    24001 gaaacagatg caaagtatat acctctaaat ccaaataaaa ttacacttag tattatcatg
    24061 tttattacag ctatccatat aaatcctgta ctcttaggaa taaccaagta agcagctgta
    24121 cttactgtca ttaatataaa tcctacaaac attactctta tagatgaacc aactttatct
    24181 gttataacac cagcaactgg agatgctccc atttttataa cataagttct tattattgat
    24241 aaagcagaaa ctagagtcat tggcattaca taaacttctg ataagtatgg acttaaataa
    24301 gttaaacttg agaatactaa ataagttgaa aatattataa gaccaattag ccaagccttt
    24361 ggcattgtaa ctacttttaa caatgactta atacttaatc cttcatctga tgctccacta
    24421 tcttttttct cttccactaa gaaaaataga agtataccac atattataga tgctgcagaa
    24481 tataaccata ctacatattt gaatcctact gttatttcag caaatttacc aaagaagtaa
    24541 agacctataa aagaaattaa tgtacctgat acacctgata acccttcata aaaaccaaat
    24601 attcttcctt gctctgactc acttccttgc attctaacaa ccttaacaga ggctgagaag
    24661 aaagttaata ttgttgtaaa tccccataat acaaatatta aaagtatcat actatatgat
    24721 gggaatgtag agaaataaaa tccaagtatt cctgaagcaa ttaaagaaaa agttattaat
    24781 tttctaactg agaatctatc tgcaaaccat cctcctataa aataagatac cattcctact
    24841 aatccatata aactcaataa gttccctatt tgtgtatgac ttaatgctaa agcttgttgc
    24901 attgggtcat aaaatgatga tttcatatat ggtaaactat acatagctgt tgttccaaat
    24961 gccaatatga atattatcaa aaatctttta acattatttt tgctttccat tgattctctc
    25021 tccttaaaat tttattgttt ataatctcat tcatataatt ttattttaat ttttctattg
    25081 cttgtttaaa atcatttatt atatcatttg aagattctaa tcctacagct attcttatta
    25141 gattttcccc attcatttga actaatgtat gctcttcccc taagcttgtt gctattgttg
    25201 caagctctaa agaattcatt aatcttctac tagcttggtc tcttgtcaat ccattgatac
    25261 catccttaag tttaaatgaa actacacctc cacctaaacc attcatttga gttttacaaa
    25321 gctcatattg aggatgagat tttaatgctg gatactttac caattccaca ttctcttctt
    25381 cctctaaaaa ttctgctact gctaatccat tttcacaatg ctttttcatc ctcatatcta
    25441 acgttttcat accccttaaa atcatccatg cactcattgg tggtaaagat gctcctgtaa
    25501 aacaacataa acttggccat ctaactaaat ctattaattc ttttgaacct gctactgctc
    25561 cccctaaagt atccccatgt ccatttataa acttagtaag actatgtatt actaaatctg
    25621 cacctaaatc tattggtctt tgtacaattg gtgtcccaaa agtactatca actatagcta
    25681 agcttttatt ttcatgagca atttctgcta ttgtttttat atctactaag tctaatgatg
    25741 gatttaaagg actttctata taaactattt tagtatttgg tctcattgct tcttttacat
    25801 tttgtggatt tactgcatct acaaatgtaa cttcaactcc aaatttagat aacaactcag
    25861 acatgaataa tttagtgtgt gaaaatattc catctgaact aactatatgg tcaccacttt
    25921 ttaccaatgc taatatagta gatgttattg cccccatccc tgatgtacta gatatggcac
    25981 tttctgcatt ttcaagcata gccaacttag cttctaactc tgtaagagta ggattacact
    26041 ctcttgtata cacatatccc catgtcatac acaactcttc aaaatgctct actgtctttg
    26101 cagcaaatgt tgctgtttga catattggtg tagccaatgc acctgttgtt gggtctgcac
    26161 tatgtcccca atgtattatt tttgtctcta aatcttgatt aatattgtta ctcattttga
    26221 tttcctccca ttttgactta tttatacaac gttttcccta ccaaatttca tcaatttagc
    26281 ttagtcttaa tacatttttt caagtatact tttttatttg ttataatttc taaaaatatg
    26341 acacttattt tgttttttta cagttctaat tataaactct atagtaacta tagagtcaat
    26401 atgtttttga tatttttttt acaatgttta aaatagtcag tacaaaaata ggtatatctt
    26461 agaataacta aagtcatcct aagatatacc tatttttata tcacaatata aataattaca
    26521 tataagcatt agttttttta tcataaatag atttttcaag atttatcatc ttttcataaa
    26581 tatattatag ttaaatattt taatattacc taacatctac aataaaatat actcttaaaa
    26641 taaaattata taattaaaaa tactctataa aagctaaaaa gtttttctat tcgctacatc
    26701 taaaaataat tagatagagg tataaatgta tttagtttat ttatacctct agtcttttat
    26761 aaattatatc tctactaaat tgatttttta gcacgaataa gtgtgctctt ggagatacca
    26821 gtcatcttca caacctctct atatggctta gaatttaata accccaatgc atattgtatc
    26881 tgttgattgc tgtatttctt tggcctacca tctttaaagt cctttttctt tttagcaaat
    26941 tcttttccta attgagtacg ttctattatc atatttctct caagttctgc aactgcaagt
    27001 aatgtagtca aaaagaattt acccattgaa gtattttcta aaaggcctat atttaaaata
    27061 tgaacactta cttctttagc aaataaacct tctattagtt gtattccttc tgatgtactt
    27121 ctagctagtc tatccagctt agttgcaaca agtaagtctc ccttttttag agatgatata
    27181 attttttcaa atttaggcct gtttgtagta gtgcctgtat aagtttcctt tattatttta
    27241 gcatcattat atttattcaa aatttcttgc tgttgctgat acaaactgtt gttgtctgtt
    27301 tgattttttg tacttacacg gcaatatcca tatataataa tcatcacttc ctaacataaa
    27361 gattttgtac agaagttacc cagaagcttg tttttactta tctttatcca ttttactaaa
    27421 acgatttttg ggtgtcaata ctgttaactt ttgacaccat aataattcct ttataatttg
    27481 tttgactatg tcaaaaatta ccaatataat gaaattaatg agtttataca aattggagga
    27541 aataatatga atagtctgtt aaaagaagca atagatgaat taaaaaacat ccattgcggg
    27601 gaagtttttt tattaaaaga attgttcaaa ggctatgaat ggaacaggtt ggagatgaat
    27661 atcagattga aattaggaaa actttttttg tatgaagtgg taactaatcc caatttaaat
    27721 gtagaggtca tcaataaaaa ttctgcttat cagcaaatgt ataaaaaaaa atagtgactt
    27781 aaatgtatat aatagtataa tcttcttatt gattcaaaag ttaaaacttt taatacaaaa
    27841 caatcattct attttaacat ttatcaatat gtctaaattt atataattaa cacatacgaa
    27901 tagtattgtt taaatcacat tatttaagat agataaatct taaccctact ccagcataaa
    27961 tactaaaata gggcttagaa ttatctatat ttttatccca taaaatgctt agctcttcct
    28021 cttgattgaa catatatatc tggggaaata caatagaagc gtaaatttat aaaatttcca
    28081 aagtcagaaa acttcagttc aaacttaggt ataccaaaac tttcaggtgc tatttcgtca
    28141 acgccaaaat agatgataat tccattatct gtaagataaa atgcttggtc ttcaggtata
    28201 actaactcaa cattagaata atacatttct ctattttcat ttatttgaga tttaatgtaa
    28261 tcagtaatta tattaatata atcaactcca tctctaaaaa tgtcattaag taaaagttct
    28321 tttccagttg tcaaatctat attgtaatta ttcaatgtat tgtatttagg cccatagtta
    28381 ttagcaaacc ccataaggtt taatatcata ctcagtacat aatttttatt aaaagtaact
    28441 gcgtaactgg tagataccca atagctttgt tttggaagtg aattttgaga agttgcgtta
    28501 ttatattctc gttcttcttc ctgtaagcca tttttaaaat tatttacagt cattcttaca
    28561 gcattgttta tgttatttaa aataactggg tttacatacg tggattgatt tctaatattg
    28621 tatataacag gatactttac atcatatgaa aaatacttac ttctttcaaa atcttcatta
    28681 aattgtacat ataatatatt atatgtacag gtatttgtag attgataatt ttccattaaa
    28741 atcctccccc ttttataaaa aaatcagata caatataata tgcttaaaac agtaataatg
    28801 ttaatggtaa atgtaaagaa tagaaagtat ctaaaacagc aaaaaatgac taattttgtg
    28861 gtataataca taggattgag agttatttta taggaggaaa aatatgttat tattagcaga
    28921 taaatggaaa gattatgaac ttatagatat gggaaatgga gaaaaattag aacgttgggg
    28981 aagttatgta cttagaagac cagacccaca ggttgtatgg ccaatggaat ctgaatgggc
    29041 tttatggaaa aaccctcatg gacattatca cagaagcaat aaaggtggag gtcaatggga
    29101 acacaaaaaa agatatccag aacaatggac tataaattat aaaaacttaa agtttcacat
    29161 taaaccaact ggctttaaac atactggatt attcccagag caagcagcta actgggattg
    29221 gatgatagag aaaataaaga aagctaacag acctataaaa gtgttgaatc tttttgcata
    29281 tacaggtgga gctactgtag catgtgcatc tgctggtgca gaagtatgtc atgttgatgc
    29341 tgcaaaaggt atggttaatt gggcaaaaga aaatatagaa ttatcaggtc ttaaaaatca
    29401 aacagtaaga tttatagtgg atgatgttgt aaagtttgtt gaaagagaaa taagaagagg
    29461 taaaaaatat gatgcaataa taatggaccc tccttcttat ggaagaggtc ctaaaggaga
    29521 agtatggcaa atagaagaaa agttatacag ttttgtagat ttatgtatgg gagttttatc
    29581 agataaccct ttatttttct taattaattc ttatacaaca ggattttctc caatagttct
    29641 tgaaaatgta ttgtctacaa caataggtaa aaagacaaat acaggagata tatacggtgg
    29701 ggaattagga ataccagctt ccagagatgg taagatactt ccttgtggta tatttggaag
    29761 atgggagaaa aaataatgat aaaagtcata tatgaagata accatttatt agttgtagaa
    29821 aaaccagtta acatattgtc tcaaggagat aatactaatg ataaagatat ggtaaatctt
    29881 ttaaaagact atattaaaaa aaagtataac aaacctggaa atgtatatat tggtttaata
    29941 catagattgg atagaccagt aggtggagtt atggtgtttg caaaaacatc aaaagcagca
    30001 tctagattgt ctgagcaggt aagaagtaag actttcaaaa aaacttatct agctgttgtt
    30061 catggcaaga taaaatctaa ctcagatata ctaaaagatt ttttatataa aaataaaaaa
    30121 actaatatgg taactgtagt gaaaaaaagc cataaagatg ccaaagaagc tgaacttaac
    30181 tataatgtat tagattttaa agaaaatcta agtttagttc aagttaattt aaagactggt
    30241 cgttctcatc aaataagagt tcaatttgca agcagaaaac atccattata cggagaccaa
    30301 agatatggca aagaaataaa taagattgga caacaaatat ctctttggtc caataagata
    30361 gaaatttgcc atcctactac aaaagaaaaa atggaattta catgtcatcc acctgacaaa
    30421 tatccatgga atatatttta aatctcaaat gaggtgatta tatgagtaaa aaattttcaa
    30481 taggagaaat gtctaaactt cataaaataa gcatacagac actaaggtac tatgaccaaa
    30541 tagatttatt taaacctgtt catgttgacc aagaaagcaa ttacagatat tactcaattg
    30601 accaattttc acaattagat attataaaat atttaaaata tttaggtatg cctttaaaag
    30661 aaattaagtc aaagcttgat gaaaataatg aagaaattct aaaattacta acaaataaaa
    30721 ttaatatagt ggatgaaaaa attaaagaat tagagcttat aaagaaggta ctaagcacaa
    30781 agaaagaaac tatggaaaaa ggtatgaaag tagatgaagt tggtaaaata gtgagaaaac
    30841 atattccacg aagaagtatc ttatctatag agtatgaaga aggattaagt agtgaagaaa
    30901 ctatggaact ttccagaaga caaatagcaa atatattaga agataatata tctgtgttct
    30961 atggtggagt aagtggactt gtatctatag ataaattttt aaaagaagat aaagttattt
    31021 atgacaatag ttttgttact gttgaaagag acttatttga tataaaatca caaaaacata
    31081 taacagaaat ttcatctggt gattttattt gtatgacata taaagggcct tacaaagaaa
    31141 attataccgc ttttaagaaa ctggttgatt atgttgaata taaaagaata cctattgaaa
    31201 attatatata tgaaatacct ataatagacc ctctgtctac aaacaacgaa gaggaacttc
    31261 taacagaaat tcaaatacaa gttaaaaaga gagaaattga cttaagatgt ctagtgtagt
    31321 aatctagttt acttacacat cttaatatag ttgtctatta tcaacatatg atttttctag
    31381 atagtgattc ctaacagtga gattttcaaa aaataggagg aaatatggct aatgctaatt
    31441 ccctcctatt tttaattaag ccatatcatt ttaattaagc catgtcatca cgaagtgcat
    31501 caataatatt ttcttttttt atcttattaa tagtatacaa cattgtaata aatactataa
    31561 ataaaacact aaatatacta attccaatac taaaccatgg aatcacaaaa tcaatatcat
    31621 ctgtaaccat tactttatga attagccatg aagaaattac tgctatagga agtccaaaga
    31681 acaatgctct catgccataa aaggcacact caaaattcat catcttttgg aaatcatgct
    31741 cagacattcc tacagagcga agcatggcaa gttctctacg acgtaactta atattagttg
    31801 aaattgtatt aaacacattg gcaatcgaaa tcagagaaat cataattatg aaagtataag
    31861 caaaaacatt ggcaataaaa atgtaattac ggttctcatc catcattcca tacatattgt
    31921 acagattgta ctcattcgta actccctcac tctcaataat ttgctccatt tctgcaactg
    31981 actgagtagg atttttcgat tgaaagctta aactttcaat tcctgtagaa acaccaggaa
    32041 tctcaaactt atctttggct gaataaggag ccaatactct gaagcttgct ttcttcacat
    32101 ctgaacttct gattcctgga ggagaatcag gtggcactac tttgacaaat gaaatattca
    32161 cattttgtct ctcaggtatc tccaacttgc cattagtttc aggagtgagg ctaacattca
    32221 tagaagaact gttgaaaata tcaataatat tattatcctt tgttaccata gaaacagcaa
    32281 tcagttttgc attttgtcca gtatattctt ctgctggtaa tccaagactt ttaataatat
    32341 tcagataagt tctatcatca agaaattgca tatctactgg taattcaagc atttcactca
    32401 tagaatgtga accctcatag ttcaaataat cgtctgtaag ctcacttact ttggcaacac
    32461 atgaataggt cataagtttc tgatacaaac cttcgtaaac accatttgca gtttttagct
    32521 tatcgtaaag cttcaacatt tcgttgtctt tcataccttg tgtagaaaaa ataatatcct
    32581 ggtcagtaac ctctgacctc tgatttgaca tctgttttag gtctgctact aaagcacttg
    32641 tagatataaa tagaactatg cttaaaacaa gcgacaatac aatacttcga taacgtttct
    32701 tgtttctttt aaagtttttc atagcaagaa ctccctcaag accataaact cgctgtgtta
    32761 gttttgatgt cttcacagat ttagattcaa tttttacctc atttgtctga cgaatacact
    32821 ccatcactgg tgtgttggca gcctttcttg ctggtatgta agcagaaatt aagattgtaa
    32881 ccatacttac cactgctgca acgatgattg cagggataga caatgttaat gtcaacggaa
    32941 cgtttacata gagaatattt gcaaagtttt tagctatgac agaaatcaca agtccaatac
    33001 tgactatacc gattgcaaca ccaattggta taccaatcgc accaatgcaa attccttcaa
    33061 atagcaccga atttcgtaac tgttttgctg tagctccaac agatgaaagt attccaaatt
    33121 gatgtgttcg ctcgttcaat gacatgttaa atgaattata tattagaaaa attgagccta
    33181 gcatgattat ggcaagcaca atgccaccaa ccgagtacaa aaacatattg aacaaattgt
    33241 tatcagaaac acctatgaag cgcaacacat tgtcattgaa aatggaagca tggtctttag
    33301 tgctacttat gtaagagcga atctgatgtg gatttttcaa tgtgacaaaa aggctaagac
    33361 tgtcagtctt gacttgttta tcttctttgg ttatcaaggt atatcctggt gcagaagatt
    33421 cttcaaatac gggctttcta cagataccca caactgtata agttttctta tcctgtggca
    33481 caaaaacttc actcccagca gtgtatgggt cactctgacc aagcttttca ttttcactca
    33541 ttcgtttccc tacatccaaa gaaatagtat cacctactgc aaatttgaca ccaccatctg
    33601 tcgcaacttt acttgaaaca agaatctctc tactattttc aggtaatctt ccagaaatta
    33661 aagttatagg caaagtatca aaagcttctt tgctaaatcc agcaataaaa agatatggtt
    33721 tatctggatt tctgttacct tcaagtgttg catagccaat attttcaaat gttgcagtat
    33781 ttgcaacttc atcattgact ctttgttcct gtacaaaaga agaatccaca tccaaaaact
    33841 ggacatgcca atcaccatat tttataatag ctccatttgt catatagttc atcaaagaaa
    33901 ctccaaaggt agtaactgct gtaatcatag cagctgacag aacaactcct ataattgtta
    33961 caagagttcg agtgcgattc tttttcaatc cttgcagagc aactttgtta aaaatgttca
    34021 ttaacgattc accttcctct catcacgcac tacttttcca tctgaaatac agataattct
    34081 atctgcctgt aaagcaatgt tttcatcatg tgtgacaata atgagagttt ggtgatattt
    34141 actatggctc tctttcagta actggataat ctcttgtcca tttttactgt ctaagctacc
    34201 tgtaggctca tcagcaagca taactgctgg tgcattcatc aatgcacgac caatggcaac
    34261 acgttgctgt tggccaccag aaagttgatt tggtaaatgt gtttttcgtt cttttaaacc
    34321 aagcaattct aacaagtcat ttaaccgttc ttgattgacc ttacgcttat ccataagtat
    34381 aggcaatgtg atattttcta ctacatttaa tgtgggtatc agattgtgaa actgataaat
    34441 caatccaact tgtcgcctac gaaaaatagc aagtttttca ttgctttggc catatacatc
    34501 ttgcccctcc agatatatct ttccacttgt tggtacgtct actcctgcaa tggaatgtag
    34561 tagtgtagat ttaccagaac cagaagaacc aatgattgca gtaaactctc ctttttcaat
    34621 agtaagtgag acatggtcaa gtgcagtaac cttattttca ttcttaccat aaaccttaca
    34681 taaatcttca atctttaaaa acgccattat ataagtctcc tttcatattt tataaatata
    34741 tcataggact ttcaacttac atttaagtga catttaaatg agagattcgt cactttggaa
    34801 aacgaataac aaatattgca ccaccttgtg ggtgattttg tgcagtaatt gttcctcctt
    34861 gtctcataat aatcgtctta caaagtgcca atcctattcc ataaccggct gtgcttgaat
    34921 ttttcccacg ataaaatctg ttaaatagac atggtaaatc ttctttttta aagcctgctc
    34981 cgttgtcatg aatagtaagt tgagtaaaca aaaagttgtc ctcacaaatg atatcaattt
    35041 ttccattatc acccacactc tccatgcagt ttttaaatat attttgaatt gcttctgaaa
    35101 gccaatttaa atcacccaaa atccttactc cttttggtat atcaatatgt aaagtgatat
    35161 tgtgcagttc catgggaatc aaaagttgat gaagtgcaga actaatcaaa ttattcacat
    35221 caatttgttc tttttgaaag actacaatac ctgcatctaa acgtgataat tttaaaaggg
    35281 aagtaatcag ccagtccatt cgtataagta attcctctgt ttctcgtatc aactcttttc
    35341 tctcatcttc atcagaagta ttctctaaca gtgacaaaat aagagttact gatgtaagag
    35401 gagtgcgaag ctggtgggct atgtcagcta gtgagtcagc aaggtgttct ttttcttttt
    35461 tcaatgcgta attttgctct ctaatacgta acgtcatttt agttatttca ctttgcagaa
    35521 tagaaagttc accctcatct gattcagcaa tatacagatg gttagcatta tgaagcacaa
    35581 gattaatttg ttctgaaatc tgtgcaatac ttttgtatcg atttttagta aacacaaaaa
    35641 atgctattcc aaaggtagtg gcagaaacaa tagaaagtat tccagtcata atactgattg
    35701 caaatcccag ggctacagtg agaatagtaa ttaataagaa taaaatagca aattttcgaa
    35761 actctctatt tcgaaacata acttcccccc aatctatacc ctgtcccacg aacagtcaaa
    35821 attatttgtg gacttgaagg gtcatcttct atcttctctc gcaagcgttt gatgtacaca
    35881 gtcaatgtgt tgtcattaac aaactcacct gccgcatccc acaattcatc aagtaatctt
    35941 accctcgtaa taatactttt aggattgcta ataaacacca ataacaaacg gtattctaaa
    36001 gctgaaagaa aaacctcatt gccattcttt ttcacaacac cggttgccgt atctacataa
    36061 agcccacaaa tttcaaaagt tgacccaaaa cgcccacttt ttcgtagtgc tgttctaatt
    36121 cgcgcaatca gttcacgtgg acgaaaaggt ttagtaatat aatcatctgc acccatattc
    36181 agtccagtaa caacacttga ttcatcaccg gaagctgtca aaaagataac aggaatgtct
    36241 tgcttttctt tgatttctgt gcaaatcgta aacccatttc catcaggtaa agaaatatca
    36301 ataagtgcca aatcaaattt attcttagca atctctacaa gtgcttcact tcttgtggat
    36361 acatgggtta ctataaatcc ttctgaatta agcaaaagaa taagattttt ggcaattgct
    36421 ttatcatcct caactaaaaa tatccgtttc atttactttc atcctccttt attttattag
    36481 ttttatatat tccagcagag caatagtaca ctactatttt acttatcatt acacaatttt
    36541 cagtagtttc ttttgttctt atataatcca tgcataatac ctccattgat ttattatatt
    36601 tcttataaca taaatacaca agataagaca aaaaacataa tgtaagtgca agttttttaa
    36661 ctcactaact tataaacata cactcctact aacactactt tcttgatgac acatcttaca
    36721 agcttatatt catacatcaa tgaaaaatta aatttatcca tttattaaaa taaaaggcaa
    36781 tagcttctat agctaatgcc ctttatctta aaatgattta aatactatac aatttttata
    36841 aatggctata aataaactcg tatagaatat aaaatttatc tacagtcttt tgttatacaa
    36901 aatttataac ctcttataga acaaatttac cactttgcaa acttatcact tttactcagc
    36961 tatattataa acttttaatt tatctttgtt taaatgtttc ttcttaactt ctactaaagc
    37021 ttttagcgta tccaaagatg tcattatttc agtagaaaat tcaatggctg ttcttctcat
    37081 cttaaatcca tctcttgtag agtcatttcc tttagttggt gtatttatta ctatatcaac
    37141 ttgtttattt cttatagcat ctaatatgtt tggtctaggc tcttcaattc tatttactat
    37201 atcagcctct attccatttt ctcttaaact cttcgctgtt ccttctgtag caacaaaagt
    37261 atatcctaat tctttcatat cttttgctat ctctataaac tcatctttat catgattatt
    37321 tacagtagca agtactactc ctctttcatc agacatatgt ctacctgctg ccaagaaccc
    37381 tttatataag gcttcttcta aattttctcc tacacctaga acttctcctg tagacttcat
    37441 ttcaggtcct agacttactt caactttaga taatttagac attgagaata ctggtacttt
    37501 tactgatact aattttggct ctttgtaaac tcctgtacta tatcctaaat cctttaattt
    37561 agctcctaac atacacttag tagccaagtc aactattggt actccactta ctttacttat
    37621 atatggaact gttctactag ctctagggtt aacctcaatt atatataatt cattttgaaa
    37681 ttctataaat tgtatattaa ccataccaag cacattaagg tctaaagcta tttttttagt
    37741 gtattctact attttttctt ttatttcatc agatatattt tgacttggat acattgttgt
    37801 actatctcca gagtgaactc cagctctttc taaatgctcc attataccag gtatcaatat
    37861 atcttcttta tcacatatag catctacttc tatttctcta ccagttagat atttatctat
    37921 aagtactgga tttttatggt ctctatcaaa tgcatcatcc aaatactgaa ttagtttttc
    37981 ttcgttataa gttatttcca taccttgacc accaagtaca taagatggtc taactaatac
    38041 tggataacct aactccttag caatttcaac accttcatta gttgtccata caccttttcc
    38101 ttttggtcta tttatatcta gtctctctag taaatcatca aatttttctc tatcttctgc
    38161 tgcatctata tctctaaagt ctgttcccag tataggtata tttttttcat gtaaaaactt
    38221 agccaatttt atagctgttt gtccaccaaa ctgtagtatt acaccttctg gtttttcttt
    38281 ttctattata tttaaaactt cttcttctgt taatggttca aaatacaact tatcagatgt
    38341 atcaaaatcc gtacttacag tttcagggtt attgtttaca attatagttt ctattcccat
    38401 ttttcttaaa gattttacac agtgaactga acaatagtca aattctattc cttgacctat
    38461 tcttattgga ccagaaccca atactacaac ttttctctta tcactaacta ctacctcatc
    38521 atattgttca taagttgaat agtaataagg tgatagagct tcaaattctc ctccacatgt
    38581 atcaaccatt ttataaactg gttgtatatt atataaactt ctcaattcat ataatttttc
    38641 tgggcttatc ttcattaagt cagatatacc tttatcagaa aatccctttt tctttaattc
    38701 atgtaaatat tctttatcta agtcttctat ttttagaact tttaactttt cttcttgttc
    38761 tactatccat ttaaatttat ttataaacca cttatcaaca ccagttattt ctgatatcat
    38821 ttctacttta tagcctcttc ttatcatttc agctaagtca aatagtctct catcatcagg
    38881 tactactact ctagccttta attcttctaa tgttctacct tctgatggag catgaaccaa
    38941 tgaatatttt cctgtttcaa gtgatcttat acctttaaga atagcagcct caaagttact
    39001 tcctatactc atgatttcac cagttgccat catcttagtt cctaattttc tattggcatg
    39061 tctaaattta tcaaatggcc actttggtat ttttactacc acataatcta atgttggctc
    39121 aaaacaagca taagtttttt tagttactgc attttctatc tcatccaaag tataacctaa
    39181 agctatctta gctgctactt ttgctattgg gtatcctgta gcttttgatg ctagggctga
    39241 tgacctacta actcttggat ttatttctat tatcgcatat tctaaactat gtgggtttaa
    39301 agctatttga acgttacatc caccttgaac ctctattgca tttattatgt ctattgatgc
    39361 ctttctaagt agttgatact cttcatcact tagagtttga cttggagcaa caactatact
    39421 gtctcccgta tgaactccaa ctgggtctac attttccata ttacatacag ttatacagtt
    39481 tccatttcca tccctcatta cttcgtattc tatttctttc caacctttta tactcttttc
    39541 aagaagaact tgtccaacag gacttagctg tagtccatgt gaaagtattt ctcttaattc
    39601 ttcctcagta tcagctatac ctccaccagt tccacctagc gtatatgctg gtcttacaac
    39661 tactggatat cctatcttat tggcaaactc aagacctgct tctaaatttg taactatatc
    39721 actaactatt actggttgat ttatttcttt cattacttct ctaaataaat ctctatcttc
    39781 gccctttttt atagattcta tagatgttcc tataactttt acattatatt tatctaatat
    39841 accagcatca tgtaattcta cagctaagtt taatcctgtc tgaccaccca tacctgcaag
    39901 taaactatct ggtttttctt tttctattat tttttctata aattctattg ttaatggttc
    39961 tatatatatt ttatctgcaa tttctttatc agtcattata gtagctgggt tactatttac
    40021 taatacaact tcaattccct cttcttttaa tgcttggcag gcctgtgttc ctgaatagtc
    40081 aaactctgca gcttgaccta ttattattgg ccctgaccct aatactaaag ttttctttat
    40141 actatctaat ttaggcataa ctctttctcc ttatctaaac aattttcaca gttcttatct
    40201 tcatcatcta tacaatcaac tttaattact ttattttatc ttaaattcaa atttactcat
    40261 caatacatct atttaataca tctatgttaa ttaaaccaaa ctttttgatt taagttattc
    40321 ttgtttttta gttagctatt ctaatgttat ttattttact aattctaaaa atttatcaaa
    40381 aatatagtca ttatcttttg gtcctgggca agcttcagga tggtattgaa cactgtatac
    40441 atctagtttc tcatgtctca ttccttcaac agtattatca tttaaattta tatgtgtcac
    40501 tttcatttgt tcaggaactt ctgaaacata ataaccatga ttttgagaag ttataaatac
    40561 ttttccttct tctaaatctt taactggatg atttccacct ctatgcccaa atttaagttt
    40621 agcagttttt cctccaagag ctaaagctaa aagttgatgt cctaagcata ttccaactat
    40681 aggtttttta ccaataagag cttttatatt ttctataaca tcttctaggt cttctgggtc
    40741 tccaggtcca tttgacaaga atattaagtc agggtttata ctcaatacat cttctggaga
    40801 tgttgtagct ggaaatattg ttatatcaca tccacgagct ataaatgatc ttaatatatt
    40861 tctttttact ccaaaatcca taacagccac ttttggacca tttcccttta tatgctctac
    40921 ttcttttctt gtaacagttc taactgcttc tgtatttgaa aacttatcca atttatgttt
    40981 aacatcttct aatttactgt cttctaatgt aattatacct ttcatggttc cattatttct
    41041 aagtatctta gtcaaagctc ttgtatctat tccttcaagt ccgataactt tattttgctt
    41101 taaatattgg tctatatcaa tttcacatct aaaattactt ggagaatcac ttttctccct
    41161 tactatgaat ccctttactt gaactttttc agactctgct gatgataaat ttataccata
    41221 atttcctaca agaggataag tcatagtaac tatttgacca tagtaagaag ggtctgttaa
    41281 aacttcacca tatcctatca ttgaagtatt aaatactact tctcctacac tttcttctaa
    41341 atatccaaat gcctttccta taaaaactgt tccatcttct aatattaacc ttgctttcat
    41401 actacagtac ctcctataat tctctttaga caaactaaag aacattaact aaatataagc
    41461 ttttaaatat ctatatctat ttttcacttt tacattctag ttttatactt atttacattt
    41521 attttttatc tttttctatt atactacaaa tttcttaaaa aaaagaagtt atctcaaaag
    41581 taaaaactcc tagaaaaaat aacctctttt ttttatttaa taattaaatt cttaaactat
    41641 acaatcaact taatttctat tcagctatat tgtaaacttt taactcatct ttatttaaat
    41701 gtttcttctt aacttctact aaagctttta gtgtatccaa agatgtcatt atttcagtag
    41761 aaaattcaat agctgttctt cttatcttaa atccatctct tgtagagtca tttcctttag
    41821 ttggtgtatt tattactata tcaacttgtt tatttcttat agcatctaat atgtttggtc
    41881 tagattcttc tactctattt actatatcag cctctattcc attttctctt aagctattag
    41941 ctgttccttc tgtagcaaca aaagtatatc ctaattcttt catatctttt gctatctcta
    42001 taaactcatc tttatcatga ttatttacag tagcaagtac tactcctctt tcatcagaca
    42061 tatgtctacc tgctgccaag aaccctttat ataaggcttc ttctaaattt tctcctacac
    42121 ctaggacttc tcctgtagac ttcatttcag gtcctagact tacttcaact ttagataatt
    42181 tagacattga gaatactggt acttttactg atactaattt tggctctttg taaactcctg
    42241 taccatatcc taaatccttt aatttagctc ctaacataca cttagtagcc aagtcaacta
    42301 ttggtactcc acttacttta cttatatacg gaactgttct actagctcta gggttaacct
    42361 caattatata taattcattt tgaaattcta taaactgtat attaaccata ccaagcacat
    42421 taaggtctaa agctattttt ttagtgtatt ctactatctt ttcttttatt tcatcagata
    42481 tattttgact tggatacatt gttgtactat ctccagagtg aactccagct ctttctaaat
    42541 gttccattat accaggtatc aatatatctt ccttatcaca tatagcatct acttctattt
    42601 ctctaccagt tagatattta tctataagta ctggattttt atggtctcta tcaaatgcat
    42661 cttgtaggta ttgagataat ttttcttcgt tataagttat ttccatacct tgaccaccaa
    42721 gtacataaga tggtctaact aatactggat aacctaactc attagcaact tcaatacctt
    42781 cgttaagtga ccatacaccc tttccttttg gtctatttat atctagtctc tctagtaaat
    42841 catcaaattt ttctctatct tctgctgcat ctatatcatc aaaatcagtt cccagtatag
    42901 gtatattttt ttcatgtaaa aatttagcca attttatagc tgtttgtcca ccaaactgta
    42961 gtattacacc ttctggtttt tctttttcta ttatacttaa aacttcttct tctgttaatg
    43021 gttcaaaata cagcttatct gatgtatcaa agtctgtact tacagtttca gggttattgt
    43081 ttatgattat agtttctatg tccatttttc ttaaagattt tacacagtga actgaacaat
    43141 agtcaaattc tataccttga cctattctta ttggaccaga acctaatact atcacctttt
    43201 tcttatcact aacaactacc tcatcatatt gctcataagt tgaataatag taaggagata
    43261 tagcatctat ctcacctgca caagtatcaa ccattttata tgctggtttg atattgtata
    43321 gacttctcaa ttcatataat ttttctggac ttatcttcat taggtcagat atacctttat
    43381 cagagaatcc ctttttcttt aattcaagaa gatagtcttt agttaaatct tcaattttca
    43441 taacttttaa tttttcttct tgctctacta tccatttaaa tttatttata aaccatttat
    43501 ctatacctgt aatttgttct atcatttcta ctttatagcc tcttcttatc atttcagcta
    43561 aatcaaatag tctctcatca tcaggtacta caactctttt ctttaattcc tcaatgcttc
    43621 tctcctcaga tggtgtgtga actaatgaat attttcctgt ttcaagtgat cttatccctt
    43681 taagaatagc agcctcaaaa ttacttccta tactcataat ttcaccagtt gccatcatct
    43741 tagttcctaa ttttctattt gcttttttaa atttatcaaa aggccatttt ggtatttttg
    43801 ccaccacata atctatagtt ggttcaaaac aagcataagt ttttttagtt actgcatttt
    43861 ctatctcatc taaagtataa cctaaagcta tttttgatga aactttagct attggatatc
    43921 ctgtagcttt tgatgctaaa gctgatgacc tactaactct tggatttatc tctataactg
    43981 catattcaaa actatgtgga ttaagtgcaa attgaacgtt acaaccacct tgaacttcta
    44041 ctgcatttaa tatatctaaa gatgcttttt taagcattgc acattctttg ttacttaaag
    44101 tttgagttgg agcaacaact atactgtctc ctgtatgaac tccgactggg tctatatttt
    44161 ccatgttaca tacaactata caatttccct ttgaatctct tattacctca tattctattt
    44221 ctttccaacc ttttatactc ttttcaatta atacttgtcc aacaggactt aattgtagac
    44281 catgtgaaag tatttctctt aattcttcct cattatcagc tataccccca ccagttccac
    44341 ctagtgtgta tgctggtctt acaactactg gataaccaat tgtaagtgca taatcaagac
    44401 ctgcttgtaa atctgtaact atatcactaa ctattacagg ctgatttatt tctttcatta
    44461 cttctctaaa tatatctcta tcttcacctt ttttgataga ttctactgaa gtacctatta
    44521 tttttactcc atatttatct agtatgcctt tttcataaag ttcaactgct aggtttagcc
    44581 ctgtttgtcc acccatacct gcaagtaaac tgtctggtct ttctttttct attatttttt
    44641 ctataaattc tattgttaat ggttctatat atattttatc tgccacttct ttatcagtca
    44701 ttatagtggc tggattacta tttattaata caacttcaat cccttcctct ttcaaagact
    44761 ggcaagcttg tgttcctgaa tagtcaaact ctgcagcttg acctattatt attggtcctg
    44821 accctaatac taaagttttc tttatactat ctaatttagg cataaatttt tctccttatc
    44881 taaatggttt ttactatctg taaataatac taaatctata ttaatgctaa gaatttatta
    44941 aatatacaat ctaaatcttc ttttgttgtg tattctggaa tgtactgaac actatatatt
    45001 ggtaattcct tatgtctcat tccttctata gtattgtcat ttaaatttat gtgagttact
    45061 tctgtatttt ctggcatttc tgaaacatta tatccatgat tttgagaagt tataaatacc
    45121 tttccagttt ctaaacattt aactgggtga ttacctcctc tatgtccaaa tacaagcttt
    45181 gaagtctttc ctcctaatgc caatgctaaa atttgatgtc ctaaacctat tcctgtcaat
    45241 ggctttttgc ctattaattt ttttatattt tcaactatat catttatatc ctctggattt
    45301 cctgggccat tagataataa gattaagtca ggatttatat ttaaaatttc ttctactgta
    45361 gtcattgctg gtactatagt tatatcacag ttacaagcct taagagactc tagtacacta
    45421 tttttaacac caaagtctat aactacaact ttagctccag taccttttat attttcaatt
    45481 tcttttcttg taacattttt tactgaatct ttgttacaat gctcttctaa tttagactga
    45541 acatcttgta atgatacatt ttctaaagtt ataattcctc tcttagttcc attgtttcta
    45601 ataattttag ttaatgctct tgtatctatt ccttcaagtc ctattacctt attttgcttt
    45661 agatatgtgt ctatatccat ttcacatcta aaattatttg ggttatcact tttttctctt
    45721 acaataagtc cttttacttg caccttattt gattcaacat cttctaaatt tattccatag
    45781 tttcctataa gtggataagt catagtaact atttgtccat aataagttgc atctgtcaat
    45841 agttctccat acccagccat tgaagtatta aatacaactt ctccaatagc ttcctttaga
    45901 tatccaaatg cttttccttc aaatactgtt ccatcttcta aaattaattt ccccttcatg
    45961 taagctacct cccaaatatt ttatctaagc attttctatt tctcttacaa tattaatagc
    46021 tgattctctt ggattttctg cttttgttat aggtcttcca acaactaaat aatgagcacc
    46081 tttttttatt gcatctgatg gagttacaac tcttttttgg tctccaacct ctgctgattt
    46141 aggtcttatt cctgggcaaa ctgttataaa atcagttcca catgcttcta ctattttatc
    46201 tacttcttgc gctgaacaaa caaccccatc tattcctgat tcttttgcca gtttagctct
    46261 ctttatagct aactcttctg ttgtcatatt acatcctatg tcctgtaaat cttggttgct
    46321 taatgaagtt aaaactgtta ctccaactac taatggcttt tctatattta atctttctgc
    46381 ttcttcccta gcaattagtg cacattgtct cattccttcc atatctgata catgtattgt
    46441 cattaaccaa acattatctc tcactgcagc tttcactgca cttttcatag tatttggtat
    46501 atcatggaat ttaaggtcta aaaatatttt tttacctttt tctttaagat aatctattgt
    46561 tttacctttt gtggcaacgt attgctctag ccctacctta aatatgtcta cactatcttc
    46621 taatctgtct attagttctt tagctttatc aaattcgtca gtatcaattg caactatcaa
    46681 tttttcttta ccatttatca tttttacatc tcctttttaa taaagcctaa ataatcataa
    46741 aaaaatcctc acaccaaaag aggcataagg attttatcta tacataactc tattcattag
    46801 ctatgagata tctttcccag tctctctgga ctagtttaaa agactttatt atatttaaat
    46861 ttttatttta tactcatcaa aaacctctag aagatttact agaggttata tactaacatt
    46921 atctataacc ctttagtctc tctggactac tttaaggaat ttagctgtaa tatttttctt
    46981 tatttatata actttatgta tctataggat aatttaaagt tttatctttt ttataattaa
    47041 accactaatt gctttttatg tcaataagtc tttgaattat tcttcatctt tatcaaacaa
    47101 ttttttctca aaatatgatt ctgcattata tattgcagca actggattat gcccagttac
    47161 tctatctttg acaactaaag ttgttatagg agcttccata tatttcatgg ctaaagtatc
    47221 gtgaccaaca cataatccaa gaattacatt aaggtcaacc ttagcttcat ttaaaaataa
    47281 agcttgtcct attggattgc acattacctc atctgaacac tttgatattg tttgagatgc
    47341 ttctagtcca attgtactct taggcattgc cccattttta catataacag aaaatacttc
    47401 aaacccatga tgttcaaata ttttttgcac tgtttgcatt tctcttttta gtccaataca
    47461 aaatgctatg ccaatctttt tataaccaca ctttttagca aactctataa tctcttttag
    47521 tctagtatat tgacaatacc cctctgcttc aactaatcca gcattataag ctatttttct
    47581 attctcttct tcttcataaa gttgctttgc tttttgttgt agttcaattt ctctagttgg
    47641 acatatcttc attaatttat ccatatttcc attagaacag cctctaagat tacattttcc
    47701 acacttatac atatccaata tccccttcca aaattttatt catcttgcga ttcttctttt
    47761 tctagagtta cattttcttc ttgggtttct tcttctggtt tcacatgctc gactacagtt
    47821 ataaaatatg attttcctat tttattcctt ataggaagtt tttcatatga aacatctatt
    47881 ttatttttta tacaagctat atcaaaatgt cttaaggcta cacctaagct aaccttattc
    47941 atatcttcac agtgtttctt aggtctcttt tcaaataaat gaagacctcg ttcatcctta
    48001 tggaaatacc acggttgaga attttttaca gatggagctc ttcttgtcaa ttctaagata
    48061 tctttccact ttctattcct atttatctta tttatcatat cttttactgg ctttctatca
    48121 ggtctagcat atctcgtcct aaacaactct tcattttttg ctggatatcc aaatgctatt
    48181 attatataag gattttctat tttgttttca tcatcttctt ctgtttttat tccagctaga
    48241 taatctaaat catcttcctc atcttcttca aaattcttat tcccaatatc tacaaattcc
    48301 aagatatctt ctctctttaa gtttccttcc aaccagcaag tagctattcc caatgttgta
    48361 aggcgcaaaa ctacaccttc tgtagcaaat cctatattct gtaaatagtc ctcacctttg
    48421 tctgatgtaa ctactatata atgaggtgcc tttactttac attccttacc catcaaaaaa
    48481 tgtattatat gacctctatc aacaacatgt gctttaatat ttaaatcttc atttaagtat
    48541 tctaaatttt tacaacttct ttttatttct tccatcaatg gcttttttat cttcttactg
    48601 gaaaaatttc ttacagattt tctataaaaa atggcttcat aaagctccat ttatgccctc
    48661 ctaactgaaa tcttctgacg tataaactct ataaatttat ataaatactt tatatttttt
    48721 atagttttat ttcctttttc ctcctgccct attttgaaat tcataagaat atctactcta
    48781 gtttaatata gcattcaaaa ggcttaaatt ctaccttatc aatgtctata cattagcata
    48841 atttttttat ttgattttct atgctaattt aaataacaac actagctatt acctttttaa
    48901 ttaagctttg ccagaaaaat tttttttcat ttataaatat ctatctcatt attatattat
    48961 aagttttttt cggtattctt gtatagcttt tcactaaaaa agtattttta tttctacttt
    49021 aatattatta tcaacaaaaa acatactgct taaataagtt tgttatcctc ataatttgtt
    49081 ttaattaaaa tatttttttt atttctcaat ctataaagta taaatatttt gaatatgacc
    49141 caaaatctaa gtaaagttat aatattttat aagttgttca atattaaaaa cataagtaat
    49201 gttataatac tttataagtt attcaatatt aaaaatatag gaggataaat atgaatttaa
    49261 atagaaattt agaaaaatac gctgaattag caataaaagt tggagttaac atacagccag
    49321 gtcaaattct acttataaag tcaccaatag aatgtgctga ttttgcaaga aatgcactta
    49381 aagaagcata taaatgtggt gctaaaaatg tttatataga gtggtctgat gaagaaagta
    49441 ctcttattaa atacttatat gctccagatg aagcatttca tgagttcccc aaatggacag
    49501 cagaacaata tgtagatata gcaaaagaag gtggggcatt tttatcagtc tatgcccaaa
    49561 atccagattt attaaaagat gttgaccctg aaagagttgc aaattttcag aaggcatctg
    49621 gaaaagcttt aaaagaatgg cgttcttaca ctctaactga taaatgtaaa tggaatatag
    49681 tctctgtgcc aacaaaagat tgggcaaaaa aagtgtttcc aaatttatca gaagataaag
    49741 caatagaaaa actgtgggat gctatattta aatgttcaag agtagatggt caggacccta
    49801 taaaagcatg ggaagaacat aatgaaaatc ttaaatctaa aatggacttt ctaaataaaa
    49861 ataactttaa aactttaaaa tataaatcct caaaaactga tttgactcta gacttgccaa
    49921 agggtcatgt ttggctaagt ggagcatcca aagaccctaa tggaataagt tttaatccga
    49981 atattccaac tgaagagatt tttggaatgc cacataagtt taaagtaaat ggaactgttt
    50041 atagtacaaa acctcttgtt tatggtggaa acataattga caatttcttc ttaacattta
    50101 aagatggtaa aataatagat ttctctgctg aaaagggact agatacacta gaaaaactta
    50161 ttgaaacgga tgaaggctct cattatttag gagaagtcgc tcttgttcca tacaactcac
    50221 caatatccaa tacggatata attttttata atactctata tgatgaaaat gcttcttgcc
    50281 actttgcaat tggttctgct tataagactt gtctggaagg tggaaataat ttaaaagatg
    50341 aagaattgga tgaacatggt gtaaatgaca gtttaacaca tgtagatttt atgattggtt
    50401 ctgctgatat ggatattatt ggtgagactt atgatggaaa gcaaatacag atttttaaaa
    50461 atggtaattg ggctttttaa catatgattt taactaaaaa gggctgatgg aagttatacc
    50521 agacttccca gcccttttta atgttgatga taaatatttt ttatattaat taatctcatt
    50581 attatagatt aattcctatt gttttaaaca taagtatcta aaacttatat ttatattata
    50641 tataaaatat cctatttagt aaaaccttta ttttaattta tatgctaaaa atttaacttt
    50701 gctatttcaa cagcagactt tgcatccttt gaataataat cagcacccat ttcttcagcg
    50761 tattcttctg tcaaaactgc acctcctaca aatacctttg catttatctc attatctctc
    50821 agtgcctgaa ttgtatcttt catactttga acagtcgtag tcataagtgc acttaatcct
    50881 actaatttta tatttctctt tttagcaact tccactactt cttcaatagg gacatcttta
    50941 cctaaatcta taacttcata tccataattt tctagcatta tttttactat atttttccca
    51001 atatcatgga tatcaccttt tactgtagca actattattt ttcctttgga tacattattg
    51061 ctacttttac ttaataaagt ttcctttatt gtatttaatg aaacttttac cgtttctgct
    51121 gattgaatca attgtggtaa aaatatatct ccactatcat atctttttcc tactttatca
    51181 agagcaggaa ttaaaatctc atctaatata taattttcat ccttctcttt taaaagattc
    51241 agtgttacat tttttgcttc atcttttaat cctctttcaa ctaaaatatc caagggcaaa
    51301 tctttatcaa tctttgtaga tgaatccgat ttttttgaat tatttatatt gctatattga
    51361 tttatatagt ttatacatcc tttatctgtg ttatttaata ttttaaaaga attgatagct
    51421 tccatcatac tatattcatt tggatttata attgctaaat caagccctgc ccctaaagct
    51481 aatgttagaa aagaagcatt aagtgctttc ctatttggaa gaccaaatga aatatttgaa
    51541 acacctaata tagtttttac tcctagtgtc tttaccattg ttatagcttt tatagtttct
    51601 attgcttctt cttgttgtgc tgaaacagtt aatgataaac agtctataaa tatatctttt
    51661 ggttttatcc cataagaaac tgctctatta actatccttt ttgctatttc aaatctttct
    51721 tcagcctttt taggtatccc cttttcatca agtgtaagtc caaccacaca tgaaccatac
    51781 tttttaacta ttggtaatat actttctaaa gactcctctt tgccatttac agagtttact
    51841 attgttctac cattataata tctaagtcct tgctctaagg cctctacatt ggaagaatca
    51901 acttgtaaag gtgtatctac tactgcttga atctctctta ttaattttgg cattagtttt
    51961 ttttcatcaa tctctggaag accaacattt actccaagta tttgtgctcc agcatttact
    52021 tgctctaaac ctaaatttat agcataatca acattttcat tttttaatgc ttcttgtaga
    52081 gattttctac ctgtgggatt caatctttct ccaacaactg taggcgattg tacttccaca
    52141 aattttgatg gtgaacagac tacacattta tcaattttct cgatacatcc ctttgtaaca
    52201 gaatttatat tctcagatat ttcttttata aaacttggat tcgtaccaca acatccacct
    52261 attatagtag caccaacttc aacgaacttt ttaacccctt caaaaaattc ttttgcatcg
    52321 acatcatata tagcctctcc atcaactata tttggaagac ctgcatttgc ttgaaccata
    52381 acagggactg tagctcttga tgctattttt tcaactattg gtaaaagttg tttaggtcct
    52441 aatgaacaat taactcctat tgcatctaca cctagacctt ctatagtagc caccatacat
    52501 tctggcatac atccagtaaa acttcttcca ccttcatcaa atgtcatagt acagaaaata
    52561 ggtaaatcag agttttcttt tgctgctaat acagctactt tagcttcata taaatccatc
    52621 atagtctcta ttactattac atcaactcca gatttaacgc cttgtagtac ttgtctttta
    52681 aatatttcat atgctttatc aaaacttaaa gtacccatag gctctagcat ttctcctata
    52741 ggaccaatat ctaaagctac atatcttggt ttagtattat ctacattttc tatagctttt
    52801 ctagccacca aaacagcatt gtcaatcact tcttctacag tatacttact atctaatttt
    52861 agttcattac atccaaaagt atttgtaaga attacattcg aacctgcctc taagtatgct
    52921 gtatgtattt ctataagttt atctggattt tgaagaccaa atacttctgg attttcacct
    52981 aactttaacc ctttttgttg aagcattgtt cccattgcac catcaaatat taatatatta
    53041 tttttcagat attgtcttat ttccacaaga gttcgctccc tttctatatg tacagtttct
    53101 atagttttta caattttcac acgacttttc tttcttagat ttatttattc ttgtattaga
    53161 aatacctata atagccacta ctgactttct cggtatcata attccattag aagtaattgt
    53221 tagacctatt tgtttttgag cattcaaaac gtttaatata tctatatttt tttctattgg
    53281 taaatctcca tatcctgggc tatatcgcat agttataaat ttatcttgct ttaaaaaaac
    53341 cttttctaaa ttattttgaa caatgtcaca cacttcttct attgctgttg ttccacatga
    53401 atcaattatt agtccttttg ttaaatttga ataagagtgt cgtcttattt ctttttctat
    53461 atctatccct atagtagctg ccataattac acactcatta cattctttta aaagttcata
    53521 tacatattta ctctctaatg ttaaatttgt tccctctaat tctacaacat tatctttatt
    53581 tattctaata ggataaatcc tagataaata tctaggattt attttatttt tagttatagc
    53641 tacacattca tcaatagtat atttaaggtc tttatctatc tcttgacctc tgtattgtaa
    53701 atatcttaaa acttcacttt gatttatgct tatatcttct cttccaatta aattattctc
    53761 catatatatt taaagaaaat cctttatcta aaacatcttt tgcatattcc tttgccccaa
    53821 ataaagataa gtctctgtag tttccacatt ctatagctgt agctgctggc attttatctg
    53881 attcaagaac tttttttaat gcttcttcta aaccaatctt aactgttttg gcatctacat
    53941 ctccccatag tattaaataa aatcctgttc tacatcccat tggagataag tctattacac
    54001 catctaatgt atctcttaaa taagtagcta aaagatgctc taaaccgtgc atagcagcag
    54061 ttccaaaact ttctacattt ggctgtaaaa atctcaagtc aaatttagtt actttatctc
    54121 cctttactcc atcaagtaca ctacactttc ttacaaaagg agcttttact tttgtatggt
    54181 ctagcttaaa actttctact ttttccatta tttaatcctc cattatactt taaaatttgt
    54241 tacattaatt ctaaaaaaaa ctcttcctat ctattattga taagaagagt atattatttc
    54301 aagtcatctc atcgttgtta gcaggaccac ctgataaaag gttggtatag gatcactgag
    54361 ctaactctct cccctaactc ttgataagta tcttattaaa ctgacttaaa ttatatatta
    54421 cttttttatt tttgtaaaca ctttattgtt ataatattta tatcacataa tcgtactttt
    54481 attttataac taagctgatt gtattattgg cagttgtact tcaaacacag tttgatattt
    54541 atcgcttgaa acagtaattt ctccatcatg taaatttaca atattttttg taatcgcaag
    54601 acccaatcca gaacctccaa catttctatt tctcgatttt tcaactctat aaaatctatc
    54661 aaatatattt ggtaaatcta acactggaat tggttcccca taatttatca cttttacaac
    54721 cgccatatct tcctttttct ctgtgactat atctacataa tgcccatctt ttccatattt
    54781 cacagcatta gttataagat tttcaaatgc tcttaccaat ttatttggat cagcttttac
    54841 aattaatttt tcttcattaa aattaattct actaaccata aattcttgtt taaaataaat
    54901 ttcaaattga gatactactt gacttaataa ctctactaaa tttatttcta ttttgtttaa
    54961 ttttattgta ttattttgca ttttagtcaa ttcaaacaaa tcatttataa gaacatttaa
    55021 atttttcgat ttttcatatg caatatcaac atagtacatc atctgaactt catctttata
    55081 cttaccttct tctatcactc ctaaataacc cattatggat gtcaaaggtg ttcttaagtc
    55141 atgtgacaca tttgttatta aatctgtttt tgtctgctga gcttgtctct cttcaatagt
    55201 tatatttcta agttgatgga ctatattatt gattttatgt gctagttcat caatatcatc
    55261 cttttcttta tcctttaata tatctaaatc atactcaata tctatacttt tttctaagtt
    55321 accttcatcc attaaattta cagcactttt aatgatttct aatttttgat tttttctatt
    55381 agtctttctt ataaaatcta caatttgctt atttctcttg tacgatataa tggaataaat
    55441 tgctaatgat gtgattgtaa ataaaaatgg ataaaataaa tcatacccta taagacttct
    55501 gaaatctctt gcttgatata caagttgatt aactacagac atatcactat tgacatataa
    55561 tgattttatt atatacatac ttgttaaaat aagcattgaa gttaaagcac agcttattat
    55621 aagatctaat atgggtcgaa acatatgatt taataaactt ttatttttca attttatatc
    55681 ctactcccca tacagtatga attatttttt ctccatctgt atatttttca attttatccc
    55741 ttattctgct catatgaacc attacagtat tattagattg gtaatatttc tctttccata
    55801 ccttttcaaa tatttcttct gtactatata ctctgccttt attatttgct agtaaatata
    55861 atatatcaaa ttctcttgat gtcaaaatta tttcatttcc agccactgtt acactatgtt
    55921 tttccttatc tataattact actccaacct ttatgacatc tttatcttca ttattagcac
    55981 cactaaaata atatgctctt ctaatcagcg acttcactct cacagtaagt tcaagtgggt
    56041 taaatggttt tgtcaaatag tcatctgcac cagtcattat cccttgtatt ttatccatgt
    56101 cttctgattt tgcacttaac ataagtattg gtatattcaa actttctcta acttttctac
    56161 aaacttctat cccatccatt ttaggcatca ttatatccaa tatcattaaa tgaatatttt
    56221 ccttttttaa aatatctaga gcctcttttc catcttcagc tttaattaca ttatatccac
    56281 tatttaaaag atatatctct ataaggtctc ttatttcctt ttcatcatcc acaacaagaa
    56341 ctgtattatt catttttaca catcctaact taatctttgt atatagcttt attcatataa
    56401 aattatacta tattttagtt agtgtaatct ataaatttat taatttctaa atttccaata
    56461 taatacaaat tatttacaca tttatattat ttattttgta aatattcttc taaagttaat
    56521 ccttttgaat aaatttcctc agcagcatcc ttaccaacat atctaatatg ccatggttca
    56581 tatgctgtac ctgttatatc ttctttacct tcaggatatc ttattataaa tccaaacttg
    56641 tgagcatttt ctgccaacca tttagcttct tttgtacttc caacaaacca tctttctgga
    56701 tttgttaaat caatacaaag tccagtttgg tgctcactgt aaccaggctt tgctacatat
    56761 gcatctgcct tttctcgccc ctgagatttt acccttcttg tataagtatc cagttgagta
    56821 tcataagatc tgtatgctga agaccctaaa aactgtattc cttctgaatt agcttgctta
    56881 actaaatctt caactgcctt tgcaggttct cctgccattt gtttttcttc ctctgttgct
    56941 tcttcaacaa aaggtatgtt taccttagta atattttcag gagtatagtt tttgctaatt
    57001 ccatttgtct tgtttaccaa taatatattt gatatactat ttgagtgatt tttattttga
    57061 gaatttgcct caacatcttg ttctgaatca tgttgagcag ctactattgg atctttatct
    57121 ttcttaagta atctatcttt agatataaat acacttataa atactactaa aataatggct
    57181 cctattaatt taaatttttt cataattaaa tcttctcctt tttgttatgt ttgctataat
    57241 gttaatttta gagtataaga cttaagtatt ttataagtaa atcttaaata aatcttaaat
    57301 ttaatatttt taaaggatgg tgataaaatg tctatacaaa aacttctaag taaagctcgt
    57361 aaggctatac aagattttga tatgatacaa gaaaatgata aaattgcggt tggactttct
    57421 ggtggaaaag atagtttaac tctacttcat atacttaaaa gttatcaaag attttctcca
    57481 caaaactttg aattgatagc cataacatta aatactggag gtgttgataa ttctccacta
    57541 gataaattgt gtaaagaaat aaatgttcct ttttatgaat ttcaaactga cataaaagaa
    57601 attgtatttg atataagaca agaaaagaat ccttgtgcat tgtgtgctaa tttaagaaga
    57661 ggtgctttga acgataatgc taaaaaactt ggatgtaata aagtagctct tggtcatcat
    57721 aaagatgatg caattgagac atttttaatg tctatgtttt atgagggtag agtaaattgt
    57781 ttttccccaa agacatacct agacagacag gatttaacag ttataagacc tatggtttac
    57841 atagaagagt atatgactaa gaaaatttca aaagattcta actatcctat tatcacaaat
    57901 ccctgccctg caaatggtca tactaggaga gagtacataa aaaatcttat tgctaattta
    57961 aataaagaga tgcctgattt taaaagaaat gtatttggtg ctttaaataa ttctgagaaa
    58021 ttgtttatat gggataaaga gaagataaaa aattttaaat aataattaaa atttttaaat
    58081 aaaaaagcaa gattgtatta attgtaaata atctttatat aatctacaca atcttacttt
    58141 tttatttatt atatgttatt atctttaatc tatattttaa tagttcttaa tagtatttat
    58201 tttgtctaat acattaatta taacttaaat attttatata ttaatttaat ctattaattc
    58261 attcaatcta ctggtttaat ccatttttac agtatataca tctacatatt ataaaaagca
    58321 aaattatatt ttctaaatat tttatgttag attataatat taaattctat tatctctggt
    58381 atattaaaaa atctaaatgg taactttgta cttccaagac ccgaactcac atataaatga
    58441 tttccattta tatcataaaa ccctttagta tatttccttc catatggagg agtaactaat
    58501 gctcccttaa taggtaatct tatttgacca ccatgactat gcccagatag aactaaattc
    58561 attgtatctt tactaagcat atctactaaa tctggttcat gtgctaacaa taaattaaaa
    58621 cttttattat ctatttgact ctccagatat tttatattag gatttccatt taatatttca
    58681 tcaacaccta atatattaat atatttatca tcttttaatt ttattttttt attttcattt
    58741 actaaaagat tgaagttgga atttttcata atctgcctat aatacctagg aagtttatac
    58801 atataatcat gattgccaaa tactgaaaat tttcccaacc tagcattcat acttgataaa
    58861 atagttgtaa tttcatctac acttggattt ttattggagt aatcaattaa atcaccagta
    58921 aatactatta tatctggatt caaagtgtta atcttattag ctactttttt gagattctta
    58981 gttgaataaa aactacctat ttgagtatct gaaatttgaa ctacttttac actttcagat
    59041 ttactctcaa ttgaatcatt ttttatcaat gctccatttt cacttatatt atattttttc
    59101 acaattaata gactcggctc tatcgcaact gagtatataa aaatcaaaat aaatattaag
    59161 ataaaaaatt ttaaaaaata cttaattttt gagttcaaaa tatctaccta cttatttatt
    59221 tttttaaact atttgcatta cagactcaac tttgttcatt tttctgtcat gcatttttgg
    59281 cttatttgct gaaaaccatt tatatgttgc tgtaagacct tcttttagta acacgtttgg
    59341 tatataaagc ccatgttcaa taagcttatt tatatcaaga ttaaagtcta tatttctaaa
    59401 tgggaaatac gttctttctc taaactctac tttttccata tctacatatt ttattatagg
    59461 ttctttgcca ataatttctc cacatgtata tataaggtca tcccaagaaa ttaactgtgg
    59521 atttgtcaca ttataggcct ctcttacatg aggatttttc attatgcttt ccaatacctt
    59581 taccaaatcc ccaatatata taaattgatt actaacttgt tttccttttg gtactggtat
    59641 cttttcattt ttttctattt tttcaaagaa ataatactct ctatataaat tattattttc
    59701 accatatatg taagttggtc taataattat atatggtata gggctattta taataaaatc
    59761 ttcagcctct tttttattta acccatattt tccccagttt tcattttcac ctttctcatt
    59821 ttcttctttt atatttcttc cactatcttt atatactgct cctgctgaca atactatata
    59881 cttttttaag ttatccatgc ttataaaatc aatcagatta cttacatctt cttttgtata
    59941 tgctgtcata tcatatatgt aatcatattt tcttcctgtg ataatgtttt ccatatcttt
    60001 tcgaactttt ctatcacaaa ttagatgttc tttaaaacca ttataatcta tttccttttt
    60061 accatttgta agtatatcaa tttgataccc acatttaatc aagcgcttag caagtgcaga
    60121 acctatgaag tcgcttccac ccataattaa aatagatttc attttaagtg catcctcctc
    60181 ttttttaaat gacttcctta actataatat catattttta aatatgcgac accattttgt
    60241 aatatttttg tctataaaag atatttataa caaaatatct tttatagact ctacattttc
    60301 gacaatataa gtaggttcac tttcactaat ctcttcaaaa gaaccatacc catacaatac
    60361 tccaatagaa tctataccta tttttttagc tccaattatg tcatactttc tatctccaac
    60421 cataataact ttatctttat cttttacatt acataggtct agtacatatt gtataacttc
    60481 atttttattc actcttgtac catcaagatt gctacctgct atatatttaa aatatctatc
    60541 tatatcaaaa tatctaagta tagtttctgc aaaaactgtt ggcttagaag ttgctactaa
    60601 taatatttta ccatttttat agagcatttc taatatctct ttcatattct cataaatttt
    60661 attttcaaat atccctttat cagcaaaata ttctctatac ttttcaacag cttctttagc
    60721 ttttttatct tcaaatttat aatactcctt gaaagtatca tgtaatggtg gtcctataaa
    60781 ttggtctaag ttttccaaat cttcttttat gccaaaacta tttaaagaat actgaataga
    60841 ctttgttatt ccttctttag ggtctgtaag tgttccatct aaatcgaata atactatttc
    60901 ataatttttt ttcatatttc agtcctccat atttgtaaaa agtaatatct tatatattaa
    60961 gtttatctat tttaaaaagc tatagtaata gaaatttcta atactatagc ttaagtacca
    61021 attaaatctt atatatttat tttaaaaata aatttaaaca gctctattta actgttatag
    61081 ctgaaactgg acatccttct tcggcttctt tacataaatc ttgtaaatct gctggtattt
    61141 ctccttcaat tgctactgaa tgcccttcat cgctcatact aaaaacgtct ggacatgttc
    61201 ctatacatgc tccacaagct acacatacat ccttatcaac aaatgctttc atactaaaat
    61261 acctccccta aaattattat tttttaattg ttgtttcctt agatatttat ccaatatata
    61321 ccaatttaaa catatattta ttattttatc actattgttt agtttattat agtattttcg
    61381 tatccatgtc tataaacttc actgcttttc atccatgatt ttacagtata ttgcaatctt
    61441 aattttttat ttaaaacaag ttcattatta ttgtagtctt ttataatatc attacactcc
    61501 tccattgtga atattgtaaa atcaccttct ccaccaatct ttattctgcc tttatttcca
    61561 tgtaaatcga aaatctttgt tgggtattca gttacttttt ctatacactt ttctagggat
    61621 atcccaagtt ccataatttt atttataaca tttaaaagag aatagtttac gtctttcatg
    61681 ttttttatat gcatatcagt acttattagg tcaggctcta aaccttgctt tattgctttt
    61741 ttaaaaactt taaaatcaaa ttggtccact ccatgacata catcgaacaa tactcctcta
    61801 ttctttgcat ttattactga ttttcttaat gtgccagatt ctttaaggat tccatttgta
    61861 ctatttccat atactggtgt aaccacatct ccttttccca aaatattcat tacttcatct
    61921 atatatgatg gatactctcc tatatatacc actaagggta aatttaattt tttagcaact
    61981 tgctttgatt tcttaattat atctatacca ctttcattag attgaaattt actcgctttt
    62041 acttttatac cctttatctt ttctatattt ttttctacaa ctgactcaac cttgtcaaaa
    62101 tttataacat ctaaagaagt tgattcattc aatatattta gtccctcatt tgtaacattt
    62161 aaaaaagaat atacttctgt tttacactca tccatatact tttttttaaa atcatagtag
    62221 tttgaaggac cagctgtacc tgcatcaaat ataactgtag aacctttttc aattccaatt
    62281 gaatcagaat ccatacctgt aggtaatttt ctcttataac aatgggtgtg aacatctata
    62341 aatcctgggg aaatatacat attatcggca tttattatct cgaactcttt atttgtaagt
    62401 aatttttctt ttcttatttt ctctttaagg ttcaatccaa tagcatatat tttcccatgt
    62461 aaaaccaaga tatctctttt ttcaaatttg ataccatctg ttggagatat tattgtccca
    62521 tttcttataa gtaaattttt catttattcc acatcctaat tacaatataa tttctctaat
    62581 agcttttctt acataaagaa aataagccta aaaataaaaa tattttagac ttattcacta
    62641 tattatacta tattaattat attaaattaa ataaaatctt taatttactt taagaagcaa
    62701 ttaagtattt gttgctcggc ttcttcttca gtaagaccta atgtcatcat ctttagtatt
    62761 tggtctcctg caatctttcc aatagctgct tcatgtacta aaagagcatc tggatgattt
    62821 gcagcaattt caggtatagc actaatttga gaatttccca taattattga atcacattga
    62881 acatgtgcag aacaaaggga atccccaata acacaaggat taaacttttg cttagaatta
    62941 tcttgcccaa ctgtacgaga aactacttga gcagaagagt tttcaccctc taagataacc
    63001 ttcatattag attctgcaac ttgattacca tgagttaata atttctcaaa tacaactatt
    63061 ttagctcctt tacctaggtt tgcatccatt tctcttttag ttgaatctac acccttaatt
    63121 tgaattgttt ccatttcaca atatgaatcc tcatccatat tgacaatagt aactggattt
    63181 aaaattctct ttccttctcc atcaccttca ccataatgtt tttctacata ttttaggcga
    63241 gctcctttac gtaagaaaaa tctatgtata ccattatgtt cactatcatc acaaccacag
    63301 ttatgtatac cacacccagc aattataaca acatctgcat tttctccaat ttcaaaatca
    63361 ttatatacca tatcctgtac accagcctct gttactatta ctggtatatg tacattttct
    63421 ccttttgtat ttggctttac tataatatct attccaggtt tatcagtttt aggaattata
    63481 gttacatttt cagttgaatg tctctctact ccttgcccat ttttacgtat attgtatgct
    63541 cctaatggag ttccacgaag ttcagcaact ttttctaaaa gatttaaatc tattttgttc
    63601 atttaatttg ccttcctttc taattaattc atgtctttca ttaattcaca acttgaattc
    63661 acttgacaca tgatttcagg taatatagcc tcttttgttc catggctttt tactgaacca
    63721 tcttgtagaa caattatttc atcagctaac tctaatattc tttcttggtg agaaattatg
    63781 attatagtct gattagactc ttcatgtatt ttcttaaaac tttcattgag ttttccaaag
    63841 ctccaaaggt ctatccctgc ttcaggttca tcaaatatag aaacctttaa atctctagca
    63901 aaaagagttg ctatctcaat tcttttcatt tcccctccag aaagagagtt atcaacttca
    63961 cgatttaaat agtcttttga acacaatcca acatctgtaa ggtattggca acatacatca
    64021 gtagacaatg gttttccatg agcaagtgta agtaaatttt caactgtcat accttttatt
    64081 cttggtggtt gttgaaatgc gtatcctatt cctttttttg ctctttctgt aatactaaga
    64141 tttgttatat cttctccatc taaaattatc tgaccactcg tagctttttc aattcccata
    64201 ataagcttag caattgtaga ttttcctcca ccatttggac ctgtgataac aataagtttt
    64261 cccctctcaa atgaaaggct aacatcattt attattccta gttcctcatt gttagactca
    64321 acattaaagg aaagattttt tatttcaagc ataatacccc tcttttctat aaaatattac
    64381 attaatatcc attcttttat tatatcagta atttttatat atcagcaact ctaaggagat
    64441 aaaatgtata ttaaataata aaacaaagtt attgaaaagt aaaaaagatg agttttatgt
    64501 aaactcatct cagaaattta gtatatcaac ttatatgtat ttaaaattta accttctata
    64561 tactctaata ttattttttg attatctttt aacataattt cttctttttt agattctatt
    64621 ccattctttt ttatctttac ctcagctaca aaggcatcat taccttcaac catttctaat
    64681 agttcatacg cttttttacg acctatttta gttgctatat cttttagtac tgccattttc
    64741 ttaaacattt tatcacctct actcaaaatt tacacttaat ttttaattat ataattctaa
    64801 tcctagacta gtttataata attattgtct ctaattatat cagatattga gtaaatttaa
    64861 tactttgtaa aattatttat cctctctgac caaataatca tttccatctt ggtctttaaa
    64921 agaaaacatc cttccatatg gcatctccat taattcccca acctcaacct cgttatttgc
    64981 catttgttca taagttccat taatatctct tgtacttaaa attattgatg gatgagatac
    65041 atttatctct ttgttttgct tcatcattag atttttatca tacaacacaa atgttgtaaa
    65101 ttcattttta cttggtgcta cttccaccca tttcatattt ggacccattt ccttttcata
    65161 agttactaca aagttcaatt tttctgtcca aaataacttt gcatcctctt gattatttac
    65221 atagagagtt atttttccta ttttatttat cataacaata cccaccttta ttattaaata
    65281 aatacctaat attttttata tttaataata tacccatata tattattttc tatagatata
    65341 tatttctaat atttatcgcc aaattatgta attctgctca atatataatt tataatatcc
    65401 atactattat agcctttatt tatgtaattt aatcacctta tatatcatac ttataattat
    65461 gataataact acataaaaaa tcacttctaa atagagttat ccatctaaaa gtgatttcat
    65521 atattctatg caactttgtg ttttagccac tttgttcctc ttaatcttaa acaatataaa
    65581 gtccctctaa caagccaatc agtatacata cctatccaaa ttcctaacac tccaaattct
    65641 aatacaaccc ccaatacgta acctgtaaaa attctaaaaa tccacatacc tattactgca
    65701 gtcatcattg tatatctaat atcaccggct ccctttagcc ctgctgataa tacaaaggat
    65761 ataggccata ttaccatagc taaacaatca cttcgaatta attgtgttga gatgtcaatt
    65821 acactagcat tttgagtata catacttgaa atccaaggtg caattggtat aaatatagct
    65881 cctactataa ataaacaaat tgttgcaaat ttagttaaat ataataaagt actcttagct
    65941 cctttaatat ctccacgtcc tatatactgt cccaccaagg ttgtagcaga caaagctaaa
    66001 gcattcccaa ttacatttat tatggatgca attgacattc ctattgcatt ggatgcaatt
    66061 gctgatgttc ccatagtaac tataaatact tgaacaatca atttacctgc attaaaaagt
    66121 agttgttcaa ctccagctgg tattcctata ttaaatatag acttttgagt ttcaacatca
    66181 atcttaaatg gaaatatttt acccatagat ataaattcgt ttcctttaaa taaagctctt
    66241 ataattacta tacatccaat tattctagct atagcaatag atatagctgc acctgttatg
    66301 ccataggatg gtgtttgcaa atttattcct agaggattta aatcaatacc atatataagt
    66361 atatatccta atgttacatt tactatattc ataaacatag tcacatacat aggtttcttt
    66421 acatctccac accctcttaa aagaccattt gctatttgtt gtgtcgcaat aaatggatac
    66481 gtaaataatg taaactctat gtataatttt gcatttgatt ttaccaattc ttctgcggaa
    66541 ccataaaata aattaattac accagttcta aaaacccaca tcaatattgt tattgtaaag
    66601 gataatatta ctccagacac tagagcctgc ttaatagttt cattcacctt ttcaccatct
    66661 ttttttccta tttgttgagc tacaacaaca gtagctccaa cagatagtgc agcaaataca
    66721 gatataaata tattgtttat tgaatcaacc attccaactg cagatacagc ttcttcccca
    66781 atatgacctg ccatcattgt attaaatact cctaaaagca tgacaaacgt ctgctctatc
    66841 attataggaa ttgctaactt tataacattt ttccttataa acatccctat tcctcttttc
    66901 cctctttata taaatttaat ttttaattag tttatcgaac tgtaaattga caatgcaaag
    66961 tttagaattg tattgttcgc attataatat actgctttca aataatataa atcttgttta
    67021 atatcatttg aacacagtat atctttataa ttatcttatg tttattattt tttatggata
    67081 ccacatttaa aatatttatt aatttaatat aaatattttc cgttattatt aaaagtagct
    67141 atatttcgtt aatattgtat cactatcgtg tagcaataac aataagtaca ttttatatat
    67201 tttttataat attatttaat catccaaact tttaccactt tttcaatata taaaatatta
    67261 cactttagat gtaacaaaat cgcatccatt taaatattgt attttataga ctaattttag
    67321 gatgtgatac tttggttaat ttaaatgcaa ataatctaaa tgtaaatatg gtttatccta
    67381 tttcttccac agcacccata cgtttcagaa gatatactgt ttcatattta gaaaacatgg
    67441 aaaatattta tttaactata gcaacatact ttgatacact tggtttaggc acaatgaata
    67501 tcgacaaagt ttatggtcaa tgggcttggt ttactgataa tatatatgat ttaaatctat
    67561 ttgtttttgt aggaaattat ccttatcaaa ttgctaaaaa cagatatgat acatttgtag
    67621 atattttgcc agtagctatt acttctattg tcaatggaga tagaatattt ttaatttcaa
    67681 atccttgttt gttaaattca aaaattacag ttagatttat atctagtcat cctactctta
    67741 atagaacagt tgattatggc aatattagag attttatttt ttaaaactgc aacatgatgt
    67801 gctattaaaa aataccctaa atttaatgat attattaaat aactagaata tttttaattg
    67861 gcacatcatg cctagctatt ataaattcat aatattattt tacttaagat aagtactgta
    67921 ttttatctac ttgtatattt ttatttacct agtttctcag ttctatatcc tatttcttta
    67981 ttagctagct tataaccttc ttgtatcatt tcttctctcg ttaatgcact ccctaataaa
    68041 ttgtcaatac tcagttgctt tctatcacta aaatacttat ccaataatga ttcctctata
    68101 tcttcctgat atgccaaatt tccttcatgc attatatatt ttacatcaaa accttcttta
    68161 tttaatactt ttcccaccaa gatacttcta tgacatctta taggttcttg catagctcct
    68221 aataaaacta tcctataacc catttgacaa ccctttttta atctttctat tccgtttaaa
    68281 aaaatatctt cttttgctac tttctcaaaa tctgcataac cttcttgcgt atatacatct
    68341 ttattagttc ttttagctcc aaattctttt cccatgtata tatataaaaa tccggaattt
    68401 ctaagagatt cgttaaatgc ctctttattg tattgaatat tatatttaga atatggagtt
    68461 tctctaatgt caactacaca atttatgtca tattttttta tcatattaat aagcttatca
    68521 tatggataat ttgaatgtcc tattgcgaat atttccatat aaacaccctc ctattctttg
    68581 aaattagtat ctatatatgt agatacccga tttacttaaa attaaataaa gtattacttt
    68641 aaatacccaa tatctttttt tcttgatatt gtatattttt ttactttata tccttaaaaa
    68701 aatatacaac tttatatata aaacatcaat atttatatat atttt
//
LOCUS       DAGQVA010000012        66675 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.012, whole genome shotgun sequence.
ACCESSION   DAGQVA010000012 DAGQVA010000000
VERSION     DAGQVA010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.012"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            835..2505
                     /locus_tag="MIV85_000916"
     CDS             835..2505
                     /locus_tag="MIV85_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBY2960285.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHKMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESSKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2627..3361)
                     /gene="pflA"
                     /locus_tag="MIV85_000917"
     CDS             complement(2627..3361)
                     /gene="pflA"
                     /locus_tag="MIV85_000917"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBY2960286.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3521..5752)
                     /gene="pflB"
                     /locus_tag="MIV85_000918"
     CDS             complement(3521..5752)
                     /gene="pflB"
                     /locus_tag="MIV85_000918"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBY2960287.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPGALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            6045..7106
                     /locus_tag="MIV85_000919"
     CDS             6045..7106
                     /locus_tag="MIV85_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBY2960288.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            7197..8810
                     /locus_tag="MIV85_000920"
     CDS             7197..8810
                     /locus_tag="MIV85_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBY2960289.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9085..11070
                     /locus_tag="MIV85_000921"
     CDS             9085..11070
                     /locus_tag="MIV85_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBY2960290.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            11075..11509
                     /locus_tag="MIV85_000922"
     CDS             11075..11509
                     /locus_tag="MIV85_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBY2960291.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11538..12098
                     /gene="srlA"
                     /locus_tag="MIV85_000923"
     CDS             11538..12098
                     /gene="srlA"
                     /locus_tag="MIV85_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBY2960292.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            12162..12530
                     /locus_tag="MIV85_000924"
     CDS             12162..12530
                     /locus_tag="MIV85_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HBY2960293.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            12555..13121
                     /locus_tag="MIV85_000925"
     CDS             12555..13121
                     /locus_tag="MIV85_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBY2960294.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            13162..13527
                     /locus_tag="MIV85_000926"
     CDS             13162..13527
                     /locus_tag="MIV85_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBY2960295.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13628..14401
                     /gene="srlD"
                     /locus_tag="MIV85_000927"
     CDS             13628..14401
                     /gene="srlD"
                     /locus_tag="MIV85_000927"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBY2960296.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            14750..17104
                     /locus_tag="MIV85_000928"
     CDS             14750..17104
                     /locus_tag="MIV85_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBY2960297.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSI
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMALHKVNYISDELD
                     TTSNKVNYVSDELDMALHKVNCVSDELDMALHKVNCVSDELDMTSNKVNYVSDELDMT
                     SNKVNYVLDELDITSNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVE
                     LERVFSKIEFKVCFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVK
                     PAHKLMDEYYFFMELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFT
                     IHNPVAWEDKKFETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNH
                     HADTLFSQHFMDKKSIAQAYINQRMAKKVGIEEKDIVILRSKKAKINVQINIDDGVGN
                     YIVKMYVGWWKKHGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            17192..17527
                     /gene="spoIIAA"
                     /locus_tag="MIV85_000929"
     CDS             17192..17527
                     /gene="spoIIAA"
                     /locus_tag="MIV85_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBY2960298.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            17541..17969
                     /locus_tag="MIV85_000930"
     CDS             17541..17969
                     /locus_tag="MIV85_000930"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBY2960299.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            17992..18756
                     /gene="sigF"
                     /locus_tag="MIV85_000931"
     CDS             17992..18756
                     /gene="sigF"
                     /locus_tag="MIV85_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBY2960300.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            19036..19473
                     /gene="spoVAC"
                     /locus_tag="MIV85_000932"
     CDS             19036..19473
                     /gene="spoVAC"
                     /locus_tag="MIV85_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBY2960301.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            19640..20653
                     /gene="spoVAD"
                     /locus_tag="MIV85_000933"
     CDS             19640..20653
                     /gene="spoVAD"
                     /locus_tag="MIV85_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBY2960302.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            20667..21029
                     /gene="spoVAE"
                     /locus_tag="MIV85_000934"
     CDS             20667..21029
                     /gene="spoVAE"
                     /locus_tag="MIV85_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBY2960303.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            21212..22228
                     /locus_tag="MIV85_000935"
     CDS             21212..22228
                     /locus_tag="MIV85_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBY2960304.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            22603..23445
                     /locus_tag="MIV85_000936"
     CDS             22603..23445
                     /locus_tag="MIV85_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBY2960305.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            23460..23924
                     /locus_tag="MIV85_000937"
                     /pseudo
     CDS             23460..23924
                     /locus_tag="MIV85_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            23911..25083
                     /locus_tag="MIV85_000938"
     CDS             23911..25083
                     /locus_tag="MIV85_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2960306.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            25127..26062
                     /locus_tag="MIV85_000939"
     CDS             25127..26062
                     /locus_tag="MIV85_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBY2960307.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(26336..29029)
                     /locus_tag="MIV85_000940"
     CDS             complement(26336..29029)
                     /locus_tag="MIV85_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBY2960308.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKDDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            29243..29941
                     /gene="yunB"
                     /locus_tag="MIV85_000941"
     CDS             29243..29941
                     /gene="yunB"
                     /locus_tag="MIV85_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBY2960309.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(30153..31160)
                     /locus_tag="MIV85_000942"
     CDS             complement(30153..31160)
                     /locus_tag="MIV85_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBY2960310.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            31388..32272
                     /locus_tag="MIV85_000943"
     CDS             31388..32272
                     /locus_tag="MIV85_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2960311.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            32474..34024
                     /locus_tag="MIV85_000944"
     CDS             32474..34024
                     /locus_tag="MIV85_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBY2960312.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETEDLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            34053..34700
                     /locus_tag="MIV85_000945"
     CDS             34053..34700
                     /locus_tag="MIV85_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBY2960313.1"
                     /translation="MKKFLNVLFSVCISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSILLFVMYKLCKSLSIKIFQC"
     gene            complement(34842..35102)
                     /locus_tag="MIV85_000946"
     CDS             complement(34842..35102)
                     /locus_tag="MIV85_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBY2960314.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCMLPHKKDNYNYIMSKFQDLVKITSKK"
     gene            35319..36602
                     /gene="hflX"
                     /locus_tag="MIV85_000947"
     CDS             35319..36602
                     /gene="hflX"
                     /locus_tag="MIV85_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBY2960315.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            36610..37287
                     /locus_tag="MIV85_000948"
     CDS             36610..37287
                     /locus_tag="MIV85_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBY2960316.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            37373..37816
                     /locus_tag="MIV85_000949"
     CDS             37373..37816
                     /locus_tag="MIV85_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBY2960317.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            38121..38765
                     /locus_tag="MIV85_000950"
     CDS             38121..38765
                     /locus_tag="MIV85_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBY2960318.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(38851..39228)
                     /locus_tag="MIV85_000951"
     CDS             complement(38851..39228)
                     /locus_tag="MIV85_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBY2960319.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(39228..39614)
                     /locus_tag="MIV85_000952"
     CDS             complement(39228..39614)
                     /locus_tag="MIV85_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBY2960320.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            39793..40548
                     /gene="nadE"
                     /locus_tag="MIV85_000953"
     CDS             39793..40548
                     /gene="nadE"
                     /locus_tag="MIV85_000953"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBY2960321.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            40631..41350
                     /locus_tag="MIV85_000954"
     CDS             40631..41350
                     /locus_tag="MIV85_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBY2960322.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(41517..42521)
                     /locus_tag="MIV85_000955"
     CDS             complement(41517..42521)
                     /locus_tag="MIV85_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBY2960323.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQEFILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            42787..43683
                     /locus_tag="MIV85_000956"
     CDS             42787..43683
                     /locus_tag="MIV85_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBY2960324.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREMNLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            43821..45083
                     /locus_tag="MIV85_000957"
     CDS             43821..45083
                     /locus_tag="MIV85_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960325.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVDYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            45159..46352
                     /locus_tag="MIV85_000958"
     CDS             45159..46352
                     /locus_tag="MIV85_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBY2960326.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            46981..47775
                     /locus_tag="MIV85_000959"
     CDS             46981..47775
                     /locus_tag="MIV85_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBY2960327.1"
                     /translation="MESVMENLNNLKVELKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            47870..49210
                     /locus_tag="MIV85_000960"
     CDS             47870..49210
                     /locus_tag="MIV85_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBY2960328.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            49347..50579
                     /locus_tag="MIV85_000961"
     CDS             49347..50579
                     /locus_tag="MIV85_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBY2960329.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            50619..51761
                     /locus_tag="MIV85_000962"
     CDS             50619..51761
                     /locus_tag="MIV85_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBY2960330.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            51772..52566
                     /locus_tag="MIV85_000963"
     CDS             51772..52566
                     /locus_tag="MIV85_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBY2960331.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            52577..53599
                     /locus_tag="MIV85_000964"
     CDS             52577..53599
                     /locus_tag="MIV85_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBY2960332.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            53698..55074
                     /locus_tag="MIV85_000965"
     CDS             53698..55074
                     /locus_tag="MIV85_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBY2960333.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(55406..55750)
                     /locus_tag="MIV85_000966"
     CDS             complement(55406..55750)
                     /locus_tag="MIV85_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960334.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            56238..57248
                     /locus_tag="MIV85_000967"
     CDS             56238..57248
                     /locus_tag="MIV85_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBY2960335.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            57384..57872
                     /locus_tag="MIV85_000968"
     CDS             57384..57872
                     /locus_tag="MIV85_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2960336.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            58048..59976
                     /locus_tag="MIV85_000969"
     CDS             58048..59976
                     /locus_tag="MIV85_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2960337.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            60153..60563
                     /locus_tag="MIV85_000970"
     CDS             60153..60563
                     /locus_tag="MIV85_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBY2960338.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            60585..60887
                     /locus_tag="MIV85_000971"
     CDS             60585..60887
                     /locus_tag="MIV85_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBY2960339.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(61104..61796)
                     /locus_tag="MIV85_000972"
     CDS             complement(61104..61796)
                     /locus_tag="MIV85_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBY2960340.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(61822..63009)
                     /locus_tag="MIV85_000973"
     CDS             complement(61822..63009)
                     /locus_tag="MIV85_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2960341.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPKKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            63345..65222
                     /locus_tag="MIV85_000974"
     CDS             63345..65222
                     /locus_tag="MIV85_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2960342.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYIEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVISCKSSYVSTNDNIISLVLAG
                     N"
     gene            65577..>66675
                     /locus_tag="MIV85_000975"
     CDS             65577..>66675
                     /locus_tag="MIV85_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBY2960343.1"
                     /translation="MNTGFPKEFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVI"
BASE COUNT        25302 a         7766 c        11910 g        21697 t
ORIGIN      
        1 atggatgtaa taattaaaat aaaaaatatt attttatatt tataaacatt gacattctaa
       61 ttttgtagtg taatcgtatt ttttattaat tcttacaaaa tcaatgaaaa taagtatatc
      121 cattttaaag tacataaatt taaaaatcca gaaaaatata cttaaattat gtaagtaaaa
      181 gaggggttga atcagttgaa aatgtaatat tagcaaatag tacatcaatc ctatataccc
      241 tgtaagcaac tctattttca tgtactaaaa atgtacctat tttattaact gaaaagaata
      301 aattaaatgt aagtacataa gaagatagaa aaaattaaaa acaaaaaata tttatataaa
      361 taaatataaa aaatgatata atccctatta aaaaatttat agatgatgaa gaaatatcaa
      421 aatcttatat tataggaaga gacacttctt tgccaaaatc tatagaaaaa caataccaaa
      481 tccaaagaga ataggcggag aaaaaaataa aataaattca agagtaatag aaaagtttta
      541 tagaataaag aactgataac tctttatata acgaaaaata gaattttaag agaaaatgat
      601 ttaataactg atttaacatg gtgttttagc aggtaaaaat aaatcaccag taatgattat
      661 agaaaaatta ctttatgaat ctcaaaaaac ttagttaaga gtaagagatt tgataagata
      721 actaaagttg gggaaatgtg tttgatgaga caaaaaatta gtaaaatagt ataatctaaa
      781 taaggatatt ttgttgatta aactacacta atagtaatat tgtaggggga aaagatgaga
      841 gaagaatcga actctttaag tttagaccat atagaaattt tctttgaact tttatctcaa
      901 agtacagaag attatatatt tttttgggat ataaatagga ataaatttaa aatttcttca
      961 gcaatttttg atgaatttaa cttaagtaaa gagatagaat ctgatttggt caattgttgg
     1021 agtaaaattg tttatccaga tgatgttcaa atatggaaag atgatataca agaattacta
     1081 catggaaaaa aaggtgagca caatttagaa tataggttga ttaataaata taaagaaata
     1141 gtatggattt cttgtagagg taaagtttat gtgtcggatg acccaaaaac tatatttcta
     1201 gtcgggagaa taaagaatat tggtgaaaaa aataaatttg attctatcac aggaacgtgg
     1261 aatagagaac aatttgaaca taaaatgaat tatcttataa aagagaaaat ttataaaaat
     1321 ggtgctatgt ttattatgga tattgataat tttaaaaata taaatgaaaa atatggacat
     1381 tcttatggtg acaaagtgtt gcgtgcaatt gctactgaag tactggaata tcttccaaaa
     1441 gatgtaagat tgtataggtt agatggagat gaatttgcat ttttttaccc tatgtgtact
     1501 aaagaaacta tagagaaaat atatgaaaag atacagatgt atacaaatac tcagcatgaa
     1561 attgaatcaa gtaagtacta ttgcacagtg actgcaggcg ttgctatgta tccagaagat
     1621 ggagataatt atttagattt atttaaacat gctgatattg cattggatat agcaaaaatt
     1681 agtggtaaaa atagaattaa gtttttttca caagagctct atgaaaataa actaaaggta
     1741 atttcaatgc aacaaaaact aagagagtgc gttgaaaata attttaatga ctttgagctg
     1801 ttttttcaac cccaggtaaa tgctgttaca aaagaggtaa taggggcaga ggtactttta
     1861 agatggcatt cgagtactta tggagaagta tctcctgttg aatttatacc aatactagaa
     1921 cagagtaatt taattatacc agttgggaag tggattataa aagaagctgt aaaacagtgt
     1981 aaagaatggc ataaaataaa tccagacttt aaaatatctg taaatgtatc gtatattcag
     2041 ttaaaggaag atttttttag agattttata gtagaatgtt tagtagagta tcaattaaga
     2101 cctgaatttt taattttgga attaacagag aattgttgga taccagatat aaatttacta
     2161 aatgataaat ttattagttt aaagggtata ggagtatata ttgcaataga tgactttggt
     2221 acaggatatt catctttaaa ttaccttaaa gaactgtctg ttaatataat aaaaattgaa
     2281 agaagttttg ttaagaatat tacatataat agttatgaat atacttttct tgaatatatt
     2341 attaaattag ctcatattat aaatttaaaa gtttgtgttg agggaataga gtcttatgaa
     2401 gagtatgata tagtaaaaag cttaggggta gatattattc agggtttttt atttggaaga
     2461 cctgtaagtg cctctgaatt ttataaattt cagctatcaa agtgatgtat ataaaatgag
     2521 atatatagta tataaaaata gggcaaagtg gaagttttga agtttattaa aaatttacac
     2581 tttaccctat tttgttatgt cttctataaa ggattaatat actacactaa ctattatata
     2641 ctttcactcc aaatttagag attatttcac tagctttttg gacatcttcc ttagtggcat
     2701 caggaacatc ttttagttca taatcgatac ctaaactttc ccatttgtgt attcccatag
     2761 aatggtatgg tagcaattca aatctttcta catttttcaa tgtagctaca aattgaccta
     2821 gtttttctaa attatctata tcatcagtaa tgccaggaac taaaacatgt cttatccata
     2881 caggaatatt tcttgattct aagtgtctag caagttttaa tgccttatcc ataccaacac
     2941 cagtcaaatc aatagatttt tcctcaacca tatgttttaa atcaagtaaa accaaatcag
     3001 tattatctaa aactgggtct atagtttcta tatctacaaa tccagatgta tccaagcaag
     3061 tgtgtatatc attttctttt gcttttttaa ataattcact taaaaattct ggttgaagag
     3121 tggattcacc accagaggca gttatacctc caccagaaaa cttcataaaa gaagtatact
     3181 taagagcatc cgttattatt tcatcaactg tgtattcttt tcctgattta atatcccatg
     3241 tatccctgtt atgacagtat ttgcatctaa gaggacaccc ctgaaaaaat aatatatatc
     3301 ttattcctgg tccatctaca gtaccaaacg tttctataga atgtatcttt cccttaatca
     3361 tagagttcac ctcacaatat attttaataa ccttatcaat agttataata tttctctaaa
     3421 aaaggccatc ttataccaga aataattcaa atataagata gccttttatt tttatttttt
     3481 acacagtagt aatcttagtt aaagtataaa aatttaaaga ctaagccatt ttaccgtgga
     3541 atgttctgtt tataacatct aattgttgct ctttagttaa ttttatgaag ttaactgcat
     3601 atccagatac tcttatagtt aattgtggat attcttctgg atgttccata gcatcttcta
     3661 aagtagctct atcaaataca tttacattta agtgatgagc attttgagcg aagtatccat
     3721 ccatcattgc agaaagattg tttattcttt cagtcatatc ttttcctaaa gcaccaggta
     3781 ctatagagaa agtattagat ataccatctt gagcatgttc atatggtaat ttagcaactg
     3841 aagataatga agctaaagca ccattagtat ctctaccatg cattgggtta gcaccaggag
     3901 caaatggagc accagctctt ctaccatctg gtgtattacc agttttctta ccataaacaa
     3961 catttgaagt tattgtaagt atagattgag ttggataaga atttctataa gttttattct
     4021 ttcttatttt attcataaag ctttcaacta actctacagc tatactatca actctatcat
     4081 cattatttcc gtattttgga taatctcctt ctatttcaaa atcaacagct attccttgtt
     4141 catttctaat agttttaacc ttagcatgtt ttatagcaga taatgagtct gcacaaactg
     4201 ataatccagc cataccacaa gccatagttc taaatatatc tctatcatgt aatgccattt
     4261 ctaatgcttc ataagaatat ttatcatgca tataatgtat tacatttaaa gtatttacat
     4321 ataatgttgc taaccaatca gtgaatggtt caaatttact cataacttca tcataatcta
     4381 agtactcaga agttataggt tcaaatcttg gtccaacttg aacaccagat ttctcatcta
     4441 caccaccatt tatagcgtat aataaagttt tagctaagtt aactctagct ccaaagaact
     4501 gcatttgttt accaattctc attgcagata cacaacaagc tataccatag tcatctcccc
     4561 agtatgctct cattaaatca tcattttcat actgtactga acttgtatct atagatactt
     4621 tagaacagaa atctttgaat ccttgaggta atttagttga ccatagaact gttaagtttg
     4681 gttctggaga aggtcctaat gtatatagag tatttaacat tctaaatgag tttttagtaa
     4741 ctaatgttct accatctatt cccatacctc ctatacactc agttacccaa gttgggtctc
     4801 cagagaatag gttattgtaa tcaggagttc ttaggaactt aaccattctt aatttcataa
     4861 caaaatggtc catatactct tgtaattctt cttctgttac gattccagct tttaaatctc
     4921 tttcaaagta tatatctaag aaagtagatg ttctacctaa agacattgca gcaccatttt
     4981 ggtctttaac agcacctaaa taaccaaagt ataaccattg tacagcttct tttgagttag
     5041 ttgctggttt tgagatatca aatccataag attcagccat ttttttaagt tcatttaaag
     5101 ctgatatttg ctcagttatt tcttctctta atctgataac ttcctcatcc atgcaagaaa
     5161 cttctaatga ttttttttgc tcatttttat cttctattaa agcatcaaca ccgtatagag
     5221 caactcttct gtagtcacca attattctac ctctaccata agcatctgga agacctgtta
     5281 ttataccaga ttttctagca gctctcattt ctggagtata aacatcaaaa actccttggt
     5341 tgtgtgtttt tctgtattta gtaaatatat cttttatttc tgggtctaat tcatatccaa
     5401 aagcttcgca tgaattttca accatcttta taccaccata tggcatgaca gctcttttta
     5461 aaggggcatc cgtttgtaac ccaactattg tttctaattc tttatctaaa tatcctggag
     5521 catatgcagc tattccagaa acagtttttg tatcaacatc taaagtacca ccattttctc
     5581 tttctttttt aaataggacc attgcttcgt cccataattt tttagtattt tcagtggcac
     5641 cagctaagaa agagtcattt ccctcatatg gagaatagtt taattgtata aactctctaa
     5701 catttatttc tttagtccat cttcctgttt taaatccttg ccatgcattc attaagtatt
     5761 tcctccttag atttaaatga taaataatac tattaaaatt aatttttata tacttaattt
     5821 attttatata tttttttaaa aatatatttt ctaatataat aatagcatat tattcgtatc
     5881 ctgtatacat aaaaaataaa aaattgtcgc tttaaagtat aaaacagatt atatgttaat
     5941 aatgtggtga aattataccc atatataaat aaaataaaac aaataaatag ctaattaagg
     6001 agaaaatatt ttttattttt tgtttaggat aaataaattt tattatggaa aaaagaaaaa
     6061 gcatacatct tcacaaactg aatatttatt taataggggg aggtgataga ttgtttatca
     6121 cagtggtatt atttttagta ggtttcctat taattactaa aggcgcagat atctttataa
     6181 attgtactgt agagataggt aaaaaaacga atatatcaga aattatactt ggagctacta
     6241 tagttagttt tgcaacaaca ttacctgagt ttacagtgtc tctacttgct tctattgatg
     6301 gtcatactac tatgagttta ggaaatgcag ttggttctat aatatgtaat acagggttag
     6361 cattagggtt ggttgttttt ataagtccat ttaatgtaga taaaaaaatg tttttttcta
     6421 agtctttact attaatagta tccgttatag ttttaatttt attgagttta gatggagtta
     6481 taacaagagg tgattcatta ttacttataa taatattaat cttttatatg gttaataatt
     6541 atagaagtgt cgttggaaaa tctgatacta aaaatagaaa tattaaaaat aacactatta
     6601 aagacatatc tactaaaaaa gggaaaaatt atagaggttt ttccgtatta gaaattgtaa
     6661 aaatactatt actttttgct acaggattga taatgatgat aataggttca caaatcctta
     6721 tagagagtgg agtaataata gctagttttt taaatatacc tcaaggtata gtaagtttaa
     6781 ctataatagc acttggaact tctctgccag agatagtttc gtcgattact gctataagaa
     6841 aaaatcatca tgaaatatca gtaggaaata ttttgggtgc aaacatattg aatatagtat
     6901 cagtaatagc tgtatcagca ataccaaata acataccaat actatctcaa aatagacaat
     6961 tggatatacc attcatgata ttattattat taatagtaat aataccaaca cttaaatcta
     7021 ataaacttag tagaatacaa ggtatattga tgttattcac atattttctg tacatatcaa
     7081 ttttgtattt catgtatatt atttaactat actgtttaaa atattaattg cagaatatcc
     7141 taaaaaagta tataatggat aggttaagat taattgataa cggagaggaa taatatatga
     7201 atataacaaa gtttgaagat ttaccaataa gtgagggaat aaaaaaagct atagctgaaa
     7261 tggggtttga agaaccatct cctatacaag cacagtctat acctgcgatt ttgtcaggta
     7321 aagacgttat aggacaagct caaactggta cgggaaaaac agctgctttt agtatcccta
     7381 tactagaaac aatagaccca aataatagaa gtttacaagc tgtagtgctt tgtccaacaa
     7441 gagaactggc aatacaagta tcaacagaaa taagaaagtt agctaagtat tcgcacggaa
     7501 taaagacatt acctatatat ggtggtcagc caatagatag acaaataaaa tctctaaaga
     7561 gtggtgtgca agttgtaata ggtacaccag gacgtacaat agaccatatc aatcgtaaaa
     7621 cattaaagat ggataatgta aaaatgatta tattagatga agcagatgaa atgctagata
     7681 tgggatttag agaagatata gaaatgattt taagtaagat tccagaagaa agacaaacaa
     7741 ctttcttttc agctactatg ccaagaggaa ttttggaatt aactaagaga tatcaaaaag
     7801 acccagagca tataaaagtt gttagaaaag aacttacagt ttcaaataca aagcaatact
     7861 atatagaaac taggtcatca aataaattag aagtattatg tagattagta gatgtatatg
     7921 accctaaact atctgttgtt ttctgtaata ctaagagaaa agcagacgaa ttggtaggag
     7981 atttacaagc aagaggatat tttgcagatg cattacatgg tgacttaaaa cagactcaaa
     8041 gagatatagt aatggataag tttagaaatg gtacaataga tatacttgtt gctactgatg
     8101 ttgcagctag aggtatagat gttgatgatg ttgaatgtgt attcaactat gacttaccac
     8161 aagatgaaga atattacgtt catagaattg gtagaactgg tcgtgctggt agagaaggta
     8221 tgtcatttac ttttgtattt ggaaaagaaa tgagaaagat gaaagatata gaaagatata
     8281 ctaaatctaa actaataaag cataatatac caacaataac tgatgttgaa gagaaaaaag
     8341 taggtacttt ctttgcacaa gttaaacaaa ctatagaaga aggtcactta actaaacaat
     8401 tacaatggtt agaaggtttc tgtaatgatg aagattatgc aatggttgat atagctgctg
     8461 cacttgtaaa actatctcta ggtgaagaaa tgaaagaaga aataatagaa gaaaaaccta
     8521 gaagagagcg tggagataga aaaggtggta ctggagctaa agatggtatg attagattat
     8581 ttatcaatat tggtagaaat caaagagtac aagcaaaaga tatagttggt gccatagctg
     8641 gagaagttgg aataccaggt aaagtagtag gtactataga tatatatgat aagtatactt
     8701 ttgttgaaat acctaaaaaa gatgcaaaaa cagtaattga aaagatgaaa gatattaaga
     8761 taaaaggtaa taagattaat atagaaaaag caaataagaa gaaaaaataa cgtatagtat
     8821 acaaaactat aattagaaaa tatataaaat aatatattgg atatttaaaa agcctgatgt
     8881 gttttcaaaa cagatagtag ataatctgta agagttaaca gcataaggct tttcttgttt
     8941 tatatgatgt tataattttc cagattgttg tgaaaaatgt atattagttc ctttttttca
     9001 aatctgattt gaaaaagaga atattaatta tctatatagt ttagattata ataaaaaatg
     9061 taagataaca aaggggagaa aaagatgtca atgacttata tggaccctag ggtttttttg
     9121 attttagaaa tggtgttaga agaagacaca aatactctag aacaattttc aaatgttttg
     9181 ggtgttagta ctaggactat cagaaactat ataaaccaga ttaatcgaga attaaaaggt
     9241 ggtattgcta aaatagttaa aaatgaaaaa ggtacatata gtataagaat tgaggatgaa
     9301 agtaaattaa ttgagattgt aaattttaat agaggaaagc tatcaaattt tataaattta
     9361 aattcacctg atgaaagaat aaattatgtt cttgatattt taactatgac caacaatcca
     9421 attaccatag atgatttggc tgaagagata tgtataggaa gaacaacatt aataaaggat
     9481 ttaaaaaaag cagacagaat tttagctgaa tatgatttag aattaaaaag gaagccaaat
     9541 ataggtatga ttttagttgg tgaagaaatg gatataagat tattaatcct tgatagattg
     9601 tatgaaaatt atattgatgt cttggaaaac gttaatcaga taaatttagt taaagattat
     9661 gatattgaat gtcttagaga tgaattaaaa aagttattta aaaaagaaga actctacata
     9721 acagaacagg tcttgagaga tgttgaaaga tatataatca tgtctgtctt aagaaatcta
     9781 aatgggtaca aatttgaaaa gatagataag agatttgaag tgataagatg ttcagatgaa
     9841 tatactttag gattaaagct caaagcttta ttggaaaaga tatttaatat agttttaaat
     9901 gaaaaagaaa ccatattttt gacaatgcca ttaataggta gaaaagctcc tagtacaaaa
     9961 ttagcactta gcagtataaa gataaatgat agcgtaaagg aagttgtaga tgaagtaact
    10021 agttttttat tagagacctc agggattgat tttaaagaag ataaaaagct tatagaaaat
    10081 ttggaatatc acttgtattt tgcacttaat agaatgagat tcaacataag ggtaaaaaat
    10141 cctcttttac aagaaataaa ggaaagatat acatttccat atagtgttgc aaagatagct
    10201 gcaatgataa ttgaggaaaa gtttgacttg aaaatatgtg accacgaaat aggatatata
    10261 gcattacatt ttggaagtta ttttgaaaaa aattcaagaa aagttctaaa tgtaaatagg
    10321 gtagctgttg tttgtggaac aggtcttggg actgcacaac ttattagaat aaagatagga
    10381 aaaatacttg gagaaagtgt agaagtaaat actttttctg atatagaagc taaagctaat
    10441 ttagatttat taaagtatta tgatttagta tttacaacag tagatttcaa aacagactta
    10501 gatgttccaa tttttagagt aaatgcgtta tttaatgaag aaagtataaa gaaagagata
    10561 gaaaatgcaa tacttttgaa aaatagtata aatcttaagt ctataaaaaa gattgaaaaa
    10621 aatatccctt ttataggtaa attaattgaa gaggataagt tctttatatt gaataagagt
    10681 acgtttatgg aaaatttaga agatatgtta gaaaaattag ttcataaagg aattattgat
    10741 atagagttca aaaaaaaggt attaaaaaga gaaaagaaat cttcaacagc attagataat
    10801 tatatagcat tgcctcactc agttaatact aatggggaaa atctttatct ggcatttgga
    10861 atattagaaa aaccagtgat ttgggataca aaggaaatta gaataataat attgatgata
    10921 attccagata agaatgtaga tagtacagac ctgataataa aaagttatga agaagtactt
    10981 gaagtaggga gagataaaaa gatggtagaa gaacttgcta aggcaaaatc atttgatgaa
    11041 ttttataaaa taattaccaa gaggaggtaa taatatggac ccagtaattt ttattatagc
    11101 atcacttatt acagtgtatt tattaaatat ttttcttgga tacttacagc ttaaagattt
    11161 taataaaaat tatattgaac taaaaagaaa aggaagagtg gcaattggca gaaaaaaagg
    11221 aagaatttca tcgggtacaa ttgtgttgat acttataaat gatgatggtg tgattgtaga
    11281 gactagaaaa atgcaaggtg ttacagtatt ggcaagagta aagtcatttg aaggtttggt
    11341 aggaaagagc ttagagtata tagaaaaatc agatttaact gtttacaata aactacttaa
    11401 aaaagcaata ctagatgcag tcaaacagta cataacattt gagaaaaata aatgtgaaga
    11461 tacaaataat ctgagtactg atgaagagtg taggatggaa gtagtttaaa aaaatatatt
    11521 tataaggagg agttaatatg acgcaatttt ttcaagtatt agcaagtggt gcagatagtt
    11581 ttatgaattt atttagggca ggtgggcaac aatttgtagg ttttgtaaca gatatagtac
    11641 cacttttagt agcattatta gttacaatga atgcaattat caactttatt ggtacagata
    11701 gagtcgagag acttgcaaaa aaatgttctg caaatatatt tactagatat ttgatattac
    11761 cagtccttgg tacatttgta tttgcaaacc caatgacact atcattagga agattcttgc
    11821 cagaaaagtt taaacctagt tactttgcag cagcaagctt ttcatgccat acaatgaatg
    11881 gattattccc acatatcaat ccaggtgaac tatttatata tctaggaatt gcaaatggta
    11941 taacaacttt gggattctca acagcagatt tagcagttag atatttgtta gtgggtatag
    12001 ttgcaaactt tattaaaggt gtagttactg actatacaac aaaatttgta gagaaacaac
    12061 aaggaatagc attaaattca gatataaaga ttggataatt actttaaggt ataaataaat
    12121 ttttcaaata aaaagatagt gtatagagga ggataaatta tatggcattt aacaaagtta
    12181 aaatagtaaa aggttctgga ggatggggtg gaccattgat aatagaacca acagaaaaga
    12241 agaataaggt agtatatgtg actgggggag caaagccaga aactgcagta aaaatagctg
    12301 aacttacagg atgtgagtta atagatggat tttcacaggg tgttaaagat gatgaaatcg
    12361 catgtgtaat aataaattgt ggtggaacat tgagatgtgg tatatatcct caaaagaaaa
    12421 taccgactat aaatataatg aaaacaggaa aaagtggacc attagcaatg tttataaaag
    12481 aagatatata tgtttcaggg gtaaaaccaa caaatgtaga gcagttataa ttgaggtagt
    12541 aggagggaag aaatatggct tatgatacta aaaagaagat aagtgagcag agtcaaggaa
    12601 ttgttgcaaa aataggtata gcactaggaa atgtgacaag tactcttttt caagctggta
    12661 gggatactat agatacatta atacatacta tactgccttt tatggctttc gttgcagtcc
    12721 taataggtat aataaatcaa tcaggtatag gaaattgggt agccaattta cttactccat
    12781 taatcggaaa tgttggaggt ttagttgtct tatcaataat atgttcattt ccgttgttgt
    12841 ctccgtttct tggaccagga gctgttatag ctcagatagt gggggtattg gttggtacag
    12901 aaataggaaa aggaaatatt ccaccaagtt tagcattacc agcattgttt gcaataaact
    12961 cacaagcagc ttgtgacttt ataccagtag gtcttggtct tgcagaagct gaacctgata
    13021 cagttcaagt aggagttccg tcagttttat attctagatt tttaacaggt gcaccaactg
    13081 ttctattagc atggttagca agctttgggt tatataaata gaagaatact ttataaataa
    13141 ttagagagag gttcagttga tatggaatta atatacagta ctcaaataaa taaaatagga
    13201 gataatgcaa atgaattttt acaacataat atgtttgtaa ctttcaaaga taatgctcct
    13261 caagagttag aaaattactg ttatatacat tctgaaaata atttagtaaa agaaatactt
    13321 acggatgatg tgctatcaat aaataatgtt gattacaaaa ttacttctgt tggtgagtta
    13381 gtaaaccaaa atctttcaga attaggtcat ataacattta agtttacagg tgaaaaagat
    13441 ggagcaattg gaggaacctt atatcttgaa gaaaaagaaa tagcacctat tggcgtaggt
    13501 actatactaa aaataattag aaaataaaat ttaaaacgaa tctaatcata ttataagtaa
    13561 attatagata aaagtcaatt taactaatca agttaacttt taatgtgata aaaaagggga
    13621 aatgaaaatg agaaaagtgg ctttagtcgt tggaggagga agaagtttag gtgaatattt
    13681 atctaaacat ttagctaaag taggttatga tgttgctatt gcagatttaa atgaagacaa
    13741 cgcaaaaaaa gtagctgaag aaataaaaac tgaatttggt tgtaaatctg taggatatag
    13801 ttgtaatgcc atagatgaaa gacaggttat aagtactgtc aaagctattg aaaatgattt
    13861 tgatagaata gatttattag tgtacaatgc aggagtggct gtaagtaaaa aaataactga
    13921 ttttggatac aaagatttta aatttattgt agacgtaaat ttaaatgggt actttctatt
    13981 tgcaagagaa gtatctaaag tcatgatagc aaaaggtatt gagggtagaa taatacagat
    14041 aaattcaaaa tcaggtagag tgggaagcaa gcataattca ggatattcag caggtaaatt
    14101 tgctggagta ggacttactc aaagtttagc gctagatttg gcagaacata agataactgt
    14161 aaatgcactg atgctcggta atttacttga ttctgatatg tttgaaagtt taattcctca
    14221 atatgcagta aaattgggaa tacctgaatc agaagtcaag caagtttata tagataaagt
    14281 acctttaaaa agagggtgta gatttataga tgttgcaaat atgcttacat tttatgcttc
    14341 aaaggaagct gaatactgca ctggtcaatc tataaatatt actggtggac aagttatgta
    14401 aggtttttat ggagtgtcta aagatgaact ctttagttca tgaggcactt ttttgtataa
    14461 aattaaatat attttcagca tttaaacaat gaaaaagagg tttatcttta ttttgagata
    14521 gcctcatttt tgtaattaaa aaacatagtg tttaagtaaa catataagat tgttagtttt
    14581 ttaaaagaga attttttaat aatattatat ttatgaagta tttttaaact taatttgata
    14641 aaatatagct atgttttata tactgtagtt ttgaacatag aaagtttaat aaattatagt
    14701 atatatgtta atttttaata aggtaagaaa gtagaaagaa ggatatttta tggatataat
    14761 aaaaaaatta agtcatgggt gtacattaga ttgtcatgac tgttgtaaat tcaatgttta
    14821 tactaaagga aataatgtag taaaaattga aggagataaa aatcatcctt atacaaaagg
    14881 ttttatatgc aaaaaaggga tggcccattt agatagatta aatcataaag atagaataaa
    14941 gactcctatg cttaaagttg atggagtatg gaaagagatt tcttttgata aagctataga
    15001 aataatggca gaaaagctta catactataa agaaaagtat acatcaaagt ctatcatgca
    15061 ttatgaccaa tatggaagtg ggtctgtgct aaaatacata ggagatatat tttttaattt
    15121 ttatggaggt gttagcagac ataagggggg tccctgttgg agtgcaggga tgcatgctca
    15181 aaaatatgat tttggagtag ctaagagtca tgctatagaa gatatgttaa atagtaaaag
    15241 tatatttgtt tggggaaaaa atccagcata tactacaatt catactatgc aaataattaa
    15301 aaaagctaaa gaaaaaggga taaagatagt agtgattgac cccatatata caaaaacagc
    15361 tcaaatagca gataagtatg tacaagtaaa tcctggaaca gatggagctt tagctatagc
    15421 tatggcaaaa attatagtgg aagataaatt atatgatgaa gaatatataa actcgtatgt
    15481 tattggtttt gaagaatata aaaaatattt atcttcattg gaattaagtt ttttaattga
    15541 tgaatgtggt gttaaagaga atgatataag agagttagtg gatttatata ctaacaaata
    15601 ttcaagtata aatgttggat atgggcttca aaaatataaa aatggtggaa acacaataag
    15661 agcaatagat gctttaggtg ctataactgg tcaaatagga tttagtggtg gaggggtaaa
    15721 ctatgctaat aaagtttatc cgagtgttat aaattctgac ccttacaata gccaatcata
    15781 tggtgaagat agggagtttt atgtaagtaa tatcagtaaa tttatagaag aatctttaaa
    15841 aaatacatca aataaagtaa attatgcatc agatgaactt gatatggcat tacataaagt
    15901 aaattacata tcagatgaac ttgatacaac atcaaataaa gtaaattatg tatcagatga
    15961 acttgatatg gcattacata aagtaaattg tgtatcagat gaacttgata tggcattaca
    16021 taaagtaaat tgtgtatcag atgaacttga tatgacatca aataaagtaa attatgtatc
    16081 agatgaactt gatatgacat caaataaagt aaattatgta ttagatgaac ttgatataac
    16141 atcaaataaa acagattata tatcaaatga attgtataat ttatctaata agtcaatcaa
    16201 agataatatt cctataaaga tggctgtgat aactaaaagt aatatgctga atcaactgcc
    16261 agatttagta gaattggaga gggtgttttc aaaaattgaa tttaaagtat gttttgatat
    16321 gtttataact gatacagcta ctttatgtga catgtttata ccgtgtacaa atacactgga
    16381 gagtgaagat ataatttata gctcaatgac caatccatat ataacctata atgaaagagc
    16441 tgtaaagcca gcacataaat tgatggatga atattacttc tttatggagc tagctaaaaa
    16501 gatgggatta aatgattatc cttttgtaga aaagagaact tatttagaaa aagtgattga
    16561 accacttaag cgttttgaca aaaatctgga tatagaaaaa cttaaaaaca attactttac
    16621 tatacataac cctgttgctt gggaagataa gaagtttgag actccatctg gaaaatacga
    16681 gctttattca gaaagtataa aaaacttggg aataagtcca acacctgtat atataagcaa
    16741 taaatataaa gaaatagaag ataaaaatat ttcttttaga ttattaacta atcatcatgc
    16801 agatacttta tttagtcagc attttatgga caaaaaatct atagctcaag catatataaa
    16861 tcagagaatg gctaaaaaag taggtattga ggagaaagat attgtgatat tgaggtcaaa
    16921 aaaagcaaaa ataaatgtac aaataaatat agatgatgga gtaggtaatt atatagtaaa
    16981 aatgtatgtt ggttggtgga agaaacatgg aaatcctaat agtttaacag acactggtat
    17041 atcagatttt gggggtcagg taacatataa tgaaagtatg gtagaaataa tacgacaaaa
    17101 ctagttaaat ttcattgaag gaataaaaat ataattatag aattgattaa aagttactat
    17161 ttttacaaaa ctattgaagg agggattttt gatggtaaat tattccttag aacataagaa
    17221 tctatacata gaatttatgt gctcagaact agaccaccat gtagccaatg aaataaggga
    17281 agaaatagat aacttattaa gtgtaaatca agtaaaaaat gttgtattta attttgaaaa
    17341 tattaatttt atggattctt caggtatagg cgtcatcata ggtagatata aaaagatttc
    17401 taatgaaggg ggacgagttt cagtaattaa tataagttca cgagttaaga agatttttga
    17461 tttatctggg ttaaataaaa ttattggcat ttatgatacg tatgaagaag ctctaagttc
    17521 tttgtaggga ggagtatgtg atgaataata ttatggaagt taaattttcg gcaatatctg
    17581 aaaatgaaag tttagcaaga gttatagtag catcctttgc agctaagtta gacccaacag
    17641 tagatgagtt agtagatata aaaactgctg tctctgaggc tgttacgaat gctataatac
    17701 atggatatga agaagacagt tctaagtttg ttttcttaag atgtgagata gaaggaaata
    17761 ctataaagat tatagttgaa gatgaagggt atggaataga aaatgtggag aaggcaatgg
    17821 aaccacttta tacatcaaaa ccagaacttg atagatcagg aatgggattc acagtaatga
    17881 aaagctttat ggacgatgta gaggtaagtt ctgtaaaaga taatgggact agaattgaaa
    17941 tgactaaaaa aataaatgtg cctaaataaa gtccaaaagt gaggttttat tatggaagta
    18001 actgttgcca gagaagaaaa aaaacctctt cttagtcatg aagagactct agaacttatt
    18061 gaaaaagttc aaaatggaga tgaagaggca aaagaaatat taatatcaag caatttaggt
    18121 ctagttagga gcgttgtatc tagattttta aatataggat atgatagaga agatttattt
    18181 cagttaggtt ctataggctt aataaaatca atatataaat ttgacccaaa atttaatgta
    18241 aaattctcta cttatgcagt accaatgatt ttaggtgaaa taaagagata cttaagagat
    18301 gatggtatga taaaagtatc aaggtcgtta aagcaaatag ctgtaaaggc aaagatggaa
    18361 agtgaagctt taactaaaaa attaggtaga gagccgagta tagaagaatt agctaaagca
    18421 atagatgtag aaaaagaaga tttagtaatg gctatggaag ctaatttcaa tgttgagtat
    18481 ttgcaaggag ttattcatga agaggaaggt tctccaatat gccttattga taaaataagc
    18541 atgaaaggag aaagtgaaga agaaaaagta gtggataaca tattgttaaa agacatactt
    18601 ggaagactgg ataagagaga gcgtcaaata atagttctca gatactttga agacatgact
    18661 caaagtgaaa taggagagat gctcaatata tcacaagttc aagtatctag gatagagaag
    18721 aaagtattgt ctaagttaaa agaatatata tcgtgataat acttatgata tgtagaataa
    18781 caaaatataa taaatatatt actaaaataa aatgtaataa ctttttatgt taagttttta
    18841 aattattaaa agatattaaa ataataaaaa gcattaaaaa agtaaaaata taaaaacaag
    18901 gtgtctttat ggaaaaatag attttttctt tattaggcat cttttttatt ttttgaccaa
    18961 actttagata gtcaaaataa ataataggtt tattttttta aaattaacaa ataatacttt
    19021 agagaggtgt ttagtatgga taaaaattat aaaaaatatg tagaccaaat aagcccaaaa
    19081 cctacatatt taaaaaacta tacacttgca tttattgtag gtggaattat ttgtatgata
    19141 gggcaagcaa taaatgattt gtatatgaaa gttggaggtc ttgataaact aggtgctagt
    19201 tctgcaacat caataacatt aatatttata ggggcatttt taactggatt aggagtttac
    19261 gacctaatag gaaaaagagc tggagctggt tctataattc caataacagg ttttgctaac
    19321 tcaatagtat ctccagcaat ggagtataaa agagaaggct atgtattagg tgtaggtgca
    19381 aacttattta aaattgcagg accagtttta gtttatggta taggttcttc tattttatgt
    19441 ggaattattt attatatttt taagatgttt tagatgattt ttatttaatt taaattttat
    19501 taattatgaa gaaggtataa aatctgaaaa tagctactaa agtaactaat tgaaaaataa
    19561 ttgtgcagat ttaattaata tttttaatta atattaaaaa tttgaatagt aaaatgcaaa
    19621 attaaaaagg tgtgaaaata tgaaaaataa aagaattgga aaaagaacag tcaagttaga
    19681 aaataaacca accataatat caactggaac tatagtaggt cctaaggaag gtgaaggacc
    19741 actaaaggac tattttgata tgattatgac tgacgattta tatggtgaaa agacttggga
    19801 attagctgaa agtaaaatgg tagagactgc atctcaacaa gctatccaaa aggcaggtaa
    19861 aaaattgtca gatgtaaatt atatgctagg tggcgattta ataaatcaaa tagttccagc
    19921 atcatttgca gcaagagaac tggctattcc atttttaggt atatatggag cttgttctac
    19981 aatggcagaa ggtctttgta taggttctat gcttatagat ggtggttttg ctgatttagt
    20041 actgtcaggt acatcaagtc actattgtac agcagaaaga caatttagat tcccacttga
    20101 acttggaaat caaaaaccaa tgacagccca gtggacagtt acaggagcag gaagtgtatt
    20161 attagctcct aatggagacg gtccaaaagt aaagtatgtt actgttggta aagtaataga
    20221 tgagggtatt gatgatggta ataatatggg accagctatg gctccagcag caatagatac
    20281 tatctactct tactttgaag atactaatga tgacccaaat agctttgata taattgctac
    20341 tggagattta ggtactcttg gaaaacagat agcagaagac tttctaaaag aaaaaggtgt
    20401 agatatatca aaagtttaca ctgactgtgg tatagagatg tttaacctta aagaacaaga
    20461 tgtccactgt ggtggaagtg gatgtgggtg ttcagctaca gtgtttgcag gatatatata
    20521 tgataagttg agaaaaaaag aatttaacaa agtaatgctt gtatcaacag gagcactact
    20581 ttcaccgaca agtacactac aaaagcagac aataccatgt gttgcacatg cagtagtaat
    20641 agtaaatgag taggaagtga tataatatgt taatggacta tgtaagagta tttattgtag
    20701 gtggaattat atgtttaata gcccaagtaa tgatggatta tttcaaaatg caaactccat
    20761 atgttatggt aacgtatgta acaactggtg tagttttaac ttttctagga ctttatgagc
    20821 cattagttaa gtttgcagca gcaggtgcaa cagttcctat aataggattt ggatattcac
    20881 ttgctacagg agtaataaaa tcaattcaaa gtgatggttt tttaggtatt tttttaggag
    20941 gtacaactgc tacagctggt ggaatagcag cagctatatt ctttggatat attatgtcag
    21001 tagtatttac tccaaaagca aaaccataaa tctttattaa aagaataata agtttttgaa
    21061 ataataactt tttataaagc aggtggatat cttttagatt ccacctattt tttatataaa
    21121 gaagcgttta cataattgaa gttgacaatt atttacaaca tagtgtagta ttatattatc
    21181 aaaataaaat gaagtgaagt aggggataaa gatggtaact attaaagata ttgcaaggaa
    21241 tctaggtatc agttattcaa ctgtttctag gtgcttaaac aataatccta atgtatctga
    21301 aaaaacaaaa aagaaagtgg tagaagaggc aaatagacta gggttccatt ttaatgtaaa
    21361 tgcaagaaat ttagcaaaaa aagaaactaa caggataggg gtaatctttt caaataattt
    21421 taatcatcaa gatactagaa agttttttag tgatataatg gatagttcta taaattctat
    21481 tgagactaat aaatacgatt ttataataca acctaataat aacattagcg gtgatagtaa
    21541 tgtatataaa atggtaaatg gacaaatggt tgacggatta gtaattgtgt ctcaatcaat
    21601 aaaaaaagaa gagtatgatt ttttaaaaga caataatttt ccacatgtat ttatatattt
    21661 taaaccatct tttataggag aagtagacaa tttcttttgg gacgataacg tgtatggagg
    21721 ttatatagct accaagcatt taattgacca tggtcataaa gatataataa cagtaacttc
    21781 agatgataag agttcaaaaa tgcatgaaga tagaaccaag ggatatttga atgctatgga
    21841 agaggcaaat ttaaagaccg aagtcattaa atctaaaatg gattttgaat ctcaagttga
    21901 atttttagaa aaatacattg ataaaataaa aaaagcttca gctatatttg tacaacaaga
    21961 tgtaccagcg atttctataa tacaagagtt aaaaactact tatggtataa atgtaccaga
    22021 agatatttcc ataatagggt ataataatat tgaattaata tcatatttta ggtcgcattt
    22081 atcaacaata gatgacccaa gagagcaagt tataaaaaat ggagtagata gtttagtaaa
    22141 tataataaat aaaaagagta cagaacacat tccaagaaaa ttatatccaa ggttaataat
    22201 acgaaatagc gttaaaagaa taaagtagta agcttttaag tatcaaacgt ttattaaaaa
    22261 tattatagat tatgtgaagt tttttaacaa ataatataaa taaaaattaa aaggagtagg
    22321 tgtatataag tacattgtac tcctttattt attgagatag tttttataat atgaatgaat
    22381 aattttattc aattatttga aaatccgtta ttttaacaat ataaattaat aaattatttg
    22441 tattttatat catgaatcta taatattttt ttgattcata actaaaagta tataaaaatg
    22501 atgaataaat atatattata cattatcaat gataggttat ataataaaat cactaacaat
    22561 tatattataa gaaaattata aaaattacaa ggaggtatag aaatgaaaga aaaagcaggg
    22621 attagaaatg ccataatagc agcctttata atcacaatat tggcagaatt aattggacct
    22681 atttcattta aagttatggg aattaatgta actttactta gtatactatg ggctatattc
    22741 ataggaatgg ctgtttctcc tcatttatta gggagagtta taccagcctt aaaaaagttt
    22801 ataggggata atgaaataaa tgtatctcca tatttattat ctttgacact atatccatta
    22861 gggataatgt ttggaattaa tgcagggcct aaagttggta tattacttca agcaggacca
    22921 gcacttttat tacaagaatt tggtcatatg ggtacaatgt tgatagcatt acctgttgga
    22981 gtagcattag gtcttggaag aagtgcatta ggtggtactt tttcattatg tcgtgacaca
    23041 gcactaggaa ttattggaga taagtatgga ttaaactcac cagaaggtat aggaacacta
    23101 ggaacttaca taagtggtag tatatttgga acattattat tttcattttt agcaccagtg
    23161 ggtgtacttt taggatttca tccatatgct ttagcaatgg catcaggaat gggtagtggt
    23221 tcaatgatgg gagctgcaac agcatcatta atgaatacgg ttccacaaat gtcagagcag
    23281 attttagcat attcagctac tagtggattg attacagctg ttactggaat atatatagaa
    23341 ttattcttat ctttaccagt agccaactac tattatagca aagtagctcc agttattgaa
    23401 agatttagag gaagaaaaac aagaagaaca agtaataaat tgtaaaggag gatatatata
    23461 tggaaaaaac ttttaagact attatggagc agataaaaat agtattgttt atatatatta
    23521 ttatttgctt tggacaaatg atagcactta agactcaggc tcaagatttg ttgattggaa
    23581 gtgtatctgg atttttgttg gtgataattg ctattataat aaagaatttt gttaaaaaac
    23641 ctaatttacc aggttttgca taggctacat tagttgcatt tgttttatcg cttccaatat
    23701 ctccagtggg ggatatcata gcaacaaatg tagggaaaat caattttatg tctacagtaa
    23761 caccattatt agcttttgca ggaatctctg taggtaacca attagatata ttaaagactt
    23821 tgagttggaa gttagtagtt atatcattta tagttatgac atctacttac tttggttctg
    23881 cttttatatc tcaaacagtt ttaagattaa atggaatgct ttaaggaggt agtaaatatg
    23941 aatgaattaa aagcaaaaat taaagaggaa ataaagttat tatctgaaga gaaaaagaca
    24001 tcatttgaaa aagtttctga ctatttattt tcaaatccag aattagcatt tgaggagtat
    24061 aagtcacaaa aagcattatg tgatttgtta gaagaaaatg aatttaatgt aactaaaggt
    24121 gtaggaggat tagaaacatc ttttgaagct gtgtattcaa atggaactaa tgggaaaaca
    24181 gttgcttttt tagctgaata tgatgcactt ccaggaatgg gacatgcatg tgggcacaat
    24241 atcataggga caagttctgt tggtgcaggt atcatattaa aagaaatcat gaaaaaacat
    24301 aatatagaag ggactgtaaa ggtttttgga acacctgcag aagaaagagt aggtggaaaa
    24361 ataactatga ttaaagaagg tgtatttaat aatgtagatg ctgcattaat tttacatcca
    24421 agtgatgctt caatgcctga tgatatatca tttgctcaag ttaatttaaa atttgatttt
    24481 actggtaagg catcacatgc tgctgctttt ccttgggaag ggaaaagtgc cttaagtgga
    24541 gtaatagcac tatttaacag tgtaaatagc atgagattac atcttaaaga ttatgcaaga
    24601 gtacatggaa ttataactga tggaggtagc atacataata taattcctga aaaatctaca
    24661 gctatattta atgtaagagc tttaagcata gaatatttaa atgagatttg tgaaatgctt
    24721 aaaaattgtg ctaaaggagc tgcaatttct actggaacta atgtagaaat agttcaatta
    24781 gatgaaatat acaaagagat taagaatgat tctgaattag tgaatatagt tagacaaaat
    24841 tttgaagttt tgggtgaaga ctatgttgaa agagatttaa gtcaaggtat aggttcaact
    24901 gatacaggaa atttaactca tgagatacct gcaatacaag catatataaa attaaaagaa
    24961 aatactgcaa ctcatacaga tgaatttgct gttgcagctg gtggtgaaga aggcaaagta
    25021 gcacttataa aagcaattaa ggtgctagca atgtgtggag tagatatttt gtatagtaaa
    25081 taatatataa ttttaaaata tattaagaaa ggaaatcaga ttagacatga tattaaaaca
    25141 agtaatagag gtttatgaca ttttagataa agcaaatgct aatggggaag aagtaaaaac
    25201 ttacttacaa ggttatggtg aagtagatgt aactgtaaaa gaattgtctt caagtaaagg
    25261 ctcaacagat ttagtaaagc ttacaattcc tgggaaaaat ggaaaattaa aaggtggaga
    25321 tgctcctact cttggcattt taggtagact aggagggatt ggagcaagac cagaagttat
    25381 aggttttgtt tcagatggtg atggagcatt ggtagcaatt gcagtggctg ctaaactttt
    25441 ggatatgcaa cgaaaagggg atatattaga tggtgatgtt gtaatttcaa ctcatatttg
    25501 cccagatgct ccaactaaag aacactatcc tactcctttt atggattctc caattgatat
    25561 gatgactatg aatgaaaatg aagttgatag tagttgtgat gcaatacttt ctatagatac
    25621 tactaaagga aatagagtaa tcaatactag aggatttgca atatcgccaa ctgttaaaga
    25681 aggctacata ttaaaaacta gtgataacct tttagatatt atgcagactg taacagggaa
    25741 atctccattt gtattccctt tgtctattca agatataaca ccatatggaa ataatctgta
    25801 tcacttaaat agtattttac aaccagcagt agctacagat gcaccaatag taggagtagc
    25861 aattacaaca gagatgcctg ttgctggatg tgctacaggt gcaactaatt ttagtgattt
    25921 agattcagct gggagatttg caattgaagt tgccaagcta tttggtagaa ataagtgtga
    25981 tttctatgat aaagaagagt gggaaatgct tattaagaga tatggcaaat taaatagatt
    26041 tcaaacattt ggtatacagt aattagaaaa atattaagtt tatataattt gtgatataac
    26101 tatttaagaa tatataaaca attaggaata aaagtaagaa taaagcactt agttaaaaac
    26161 tttaaaaata aaatatttat ttgtttatat aaaaaggagg attctggtta ttgggattct
    26221 cttttttatg aatacaaata atatattgta attataaaaa aaggagcgtt tcaaagtgat
    26281 ttttttaatc accttgagac aactccttat atttttattt aaattctatt ttttattaag
    26341 ttgctggagt tccaccacca tcaggaggag tagtagagcc accaccatta tttccaccat
    26401 tatcaggagg agtagtagag ccaccaccat tgtttccgcc attatcagga ggagtagtag
    26461 agccaccacc attatttccg ccattatcag gaggagtagt agagccacca ccattgtttc
    26521 cgccattatc aggaggtgta gaaccgccac cattatcacc tgtgttatta ttgttattat
    26581 tattttcttc tggttggtta ttgtctggtt tttttgtatc ttcagatgat ggttgagaac
    26641 ttactttagt aggagcagta ccttcaataa atgctgcttt agagccagaa gattgctttc
    26701 ctccatcctc taaattaatt tttgtaaaat atacattttt aggaacttca aattcagtaa
    26761 ccgttaaatt agcatgtatt ttttccataa ttttttccca tagttttgca gtactagtac
    26821 ttccatgtgg tacttctcta cgttttatag tgttaccaga atcatctttt ctaccagcat
    26881 catctccaat ataagttgca ccaacataat aaggagtgta accgacaaac caagcatcat
    26941 atgcactatt tgtagtacct gttttacctg ctacaggcat tccctttgga agtgtagcaa
    27001 caccaccagt accttcagta attacgcttt ctaacatatc tgtaacaaca taagctactt
    27061 cagggtctac aactttatgt tcctcaggag catttttaac taataattga ccatcaaagg
    27121 tagttatagt agtaaaaata gaaggttcta cataaatacc gtgatttgcc aatgtaccat
    27181 aagcagcagc catttgaagt ggagtaatac cattcgccat accacctagt gtcaatgatg
    27241 ggaattttct atcacttgct tcagatgaac ctgagtgatt attctttaaa gttgttatac
    27301 caaagttctt taagtaatcc atcattatat ctacacattc atcataagag tctccaagca
    27361 tttcagcagt tttgacagct atcgtgtttg aagatttagc aagtgcttta cgtaaactca
    27421 tagaaccatg accagcagta gtagttcttg gattccattt attattttct tcaaacttat
    27481 atcctcctct agaatcactt agagcagttg cttgtgttat ttttagagta tcaatagctg
    27541 gcgtatatat tgctaaaggt tttatagaag aacctggctg atgagggtta gtagcacgat
    27601 ttaaagtttt tctaccactt atatttcttc ctccagctag tgctcttatt tcaccatttt
    27661 tataatctaa gattaccatt gcagcttgcg gttggctaac tccatcagga ccaaccatat
    27721 gtcctgggaa attgctattt ctatcaaatt cttcttctaa agcatcttgc attttagggt
    27781 ctatagttgt gtttacaatt agaccaccat tgtagaataa gttttgagct tcatcatttg
    27841 tatgtccttg ttccattaaa gcatttataa cttcactttc gataaggtct tctacagatg
    27901 aagaaacttt atctgatgat tgaggcaatt ttatttctat tttagctttg attgcttcat
    27961 catattcact ttgttttata tatttcaatt ctaacatttt ctttaaaaca atttcttgtc
    28021 tttttttagc ttcaggatta cttacagcct ttctaacaac taatgtacct gcttttaatt
    28081 gtctataagt atcattagat ataagctccc aagattttat tttttcaatc atatcaaagt
    28141 ccacttgagt agggtcatct aaatcatcat cagttgtgtt aacaaaaaat aataatttat
    28201 tctctaaatc atccttagtt tcatttccct ctaatttaga agttttatag gctgaaaatc
    28261 ttgatggatt cttagttgaa ccagcaagaa gtgctgactc tgctagagta aggtcagctg
    28321 cagacttatc aaaataacca cgtgcaccag cctcagcacc tgctagacct ctaccaacga
    28381 agaagttatt taaataagtt tctagtattt tatctttact tactgtttta ctcatctcat
    28441 gtgcatagta aatatccttt attttacgag gtatagtttg ctgttcagtt gttaacagca
    28501 ttttggatac ctgcatagga atagtactac caccttgctt agtacctgta agtgtcttta
    28561 atactgacct aaataaacct ttaatatcga cacccttatg ctcataaaaa cgctcatctt
    28621 ctattgcaat tacagcatgt tgaagataag gggaaatctt atctaatgga acgggtgtct
    28681 ttttatttac acttggagct gtagataatg tttttccatt agcgtattta atagtagttg
    28741 tttggttcgt ctgtttatct aaaacagctt ctgtaactgg agttacatct cttagtgacg
    28801 caaatactag accagcagta cctgctgtac caacaactag taaaactaaa aatactatcc
    28861 caaatactct tagtttttta aatttatcgc tttttttaga ttttttcttg ttttttgttg
    28921 aacgagtctt gttagctgaa gttctattaa ttggtttatt tgtattacca gatgagctaa
    28981 ctttttttct cctgatttta tttccatttt tatcattatc gttattcata agattttaac
    29041 ctccttactt aatgcaatat tataacacaa ataggagtag ttttgtaatt aatagaaaaa
    29101 atgaatttgc tataatattc tgtacattgt atatgtataa acgtaatata ttaaaaagtc
    29161 tatattttta ttttatttat ttttgacaaa tattataaaa attatgccaa agctacatat
    29221 aaataaatag gaggggataa ttttgaatag aatagtagat agaaaaacaa aaaatgaatt
    29281 tagaaaaatc atagctattt ttttagtaat tcttttcttg tctgtattta taggcagttt
    29341 tatatatata gataaaactt taagaccgac aataacagtt ttagcagaga ctaaagctct
    29401 tgaactagca aataggtcga taaataaagc tgttgctgag atggtagaag gaaaaataaa
    29461 ttatgaagat ttaatggata tacaacttga taataatggt aaaataacta tgatacaagc
    29521 aaacactata atgatgaatg aaattgcatc tgcaatagct ttagaaatac aagatgaatt
    29581 aaaaaaggat aaaacagcaa gttcttacat acctatagga acagcattag gaagtcctat
    29641 attagctaaa tacggtccta aacttgaagt atctattgaa cctataggaa cagtatcagt
    29701 aaactttaaa acggaatttg agtcttcagg tataaatcaa actagacata gaatatattt
    29761 agaagctcaa acacaagtta aagtagtaat accacttata acttcaacaa aacaaattaa
    29821 agctcaaata cctatttgtg aaactataat agtaggtgat gttccagaaa gttatgtaaa
    29881 tattccagaa aaaaatctag gaaatgtttt acctaacact ggaaagaata ccaacaagta
    29941 atataaagtt gtatattttt aaataaattc aaaataatag tttataaata aaatttttgg
    30001 aaataatatt aatataattt taataaaaat ttatatttta tactatgtaa aatatctaat
    30061 atatttggtc tgtaggttaa ataaaagtac ctttagacca aatatattat taataactta
    30121 ataacatctt aaaacttatt tatttatatt atttacaaca tccatttaat aaatacacca
    30181 taacctacag ctgggtcgtt ttcaattgca tgtgacactg ctccgattat tttattatct
    30241 tgaactattg gagtaccact cataccttgt acaataccac cagtttgagc taaaagcttt
    30301 ttatctgtaa ttttaatttt aaaactttta ctttctggat gtttttggtt ttctatatct
    30361 ataatttcaa tattatattt tttacactta ttaaagttat cttgtaaaat tatttgtgct
    30421 tttcctaatt taacttcatc taaagatgct actttatatt tttttaactt ggaaatatca
    30481 aagttattaa tttgacctct tattccaaaa tcagtatttt ctgtaaagct accaataata
    30541 ttttctcgtt ttgcatttat acatccaaca ctacctttat aagatttttc tatattaagg
    30601 tgcttagttg tagaaattga acctgtttta ataggtattt ttcttgcatt accaacactt
    30661 attggatgac ctacagctcc aaactctgat gtatctggat tgatatacgt taaagtagca
    30721 aatccagaaa gtaaattgtt aaaactaatt ttttctaata tgtgtttggt agttttcatt
    30781 gttataagtt gtccacctct atttaataaa atagatactt gtttttcttc tggtaaagca
    30841 tttaaggtat tggcaaagtc actatatcca tcaacttcag cattatttac ctttactata
    30901 gcatcaccta atctaaatgg agatgcttct ccaggatttc taactatgat attttttaat
    30961 tctgcgtcaa tttgaagtac gtttccaatt ggtattaaat attcaggttc atttttttgt
    31021 aaattttgtg cataaattaa attatttgag aaaaaatata ataaaaataa aaatgttaaa
    31081 acaattgtaa attttgactt agctaagttg gtttttttac ttaaagtatt atttttaaaa
    31141 tgaaaatttt taagttgcat aaaacacctc tttcttatta aattatttta ataatagaat
    31201 tgaagttttc ttgctgcttc tatattatgt tgtgcaagaa tcatgttttg atgcttggaa
    31261 aactagctca ataacacctt agttttcata aaaataaata aaataaatag tgtatatgat
    31321 aaaataaata catattcata taaataaaaa taaacaataa ctgtctagca taagaaagga
    31381 gcaaaaaatg aaaaaatata gattgttagt tacttgtata attgccatgg gaatcataat
    31441 tataggaaca tcaaatccag ttagcaattt ttacaagact acaaatttga ttagttcagg
    31501 aaatatcaca aatgaaaaag cagataaaga tgaaaattca aacaaaaata ataaagataa
    31561 aaatgaagac aaatctaatt ctaaaagtaa taaagataag tcatcagagg acaaatcgtc
    31621 agataataaa aatgaaattc aaaaaaataa aaaactttta atttgtatag acccagggca
    31681 tcaaggaaaa ggagatagca atttagaacc agtagctcca ggttcttcct ctaaaaaagc
    31741 gagagtatct tcaggaacag agggtattgc tacaaaaaag ccagaatatg ttttaaactt
    31801 agaagcatct cttgttttaa agagtatatt agaatctaaa ggttataatg taataatgac
    31861 tagagagaca catgatgtaa atataagtaa ttcagaaaga gcaatacttg ctaatgacaa
    31921 aaaagcagat atggttgtaa gaatacatgc agatagttta aataattctt caaaaactgg
    31981 agcatctata ttgattcctg aaaaagatgg aaaatataca gctcctatat atgaagaaag
    32041 taataaatgt gctgaattta tcaaacagaa tatggaacaa tcaggtatac aaatcaatgg
    32101 aatcgttcaa agaggtgatt tgactggatt caactggtca aaagtaccag ctgtattagt
    32161 agaaatggga tttatgagta actataatga agaccaaatg atgtcaaatc cagactacca
    32221 aagaaaaatg atgcagtgta tagctgatgg attggatgcg tattttaaat aagatatgaa
    32281 tagagaaaaa gttaggttgg tattattttc ctaattttta tctctatttt ttattgtaca
    32341 taacacaaag aagaagttta ttttaggtta aattgtcgta aatataacta aaaatattgg
    32401 gaatacttga tttaagttta aaaagaatat attatagtat agaatgtgta aaattttttt
    32461 gagaggtgtt gaaatgctag tagtagaaaa tgtgagtcat ggatttggtg cgagaacaat
    32521 attagaaaat gtatccttta gacttagaaa aggtgaacat attgcactag ttggtgctaa
    32581 tggagaagga aaatcgagtt ttttaaatat aataacaaag aagcttatgc cagatgctgg
    32641 aaatataaaa tggtcttcaa gagctacagt aggttactta gaccaacata cggtattaag
    32701 caagggaaaa actataagag aagtgcttag agaggctttt aagcatatgt ttgacttaga
    32761 gcaagaaatg attgctatgt atgacaaaat gggagaagct agtgatgatg aaatgagtaa
    32821 gcttcttgaa gaaacagcag agatacaaac tatacttgaa aatagtggtt tttatatgat
    32881 agatgcaaag atacaagaag ttgcaaatgg tcttggtctt ggagaaattg gtcttgataa
    32941 agatgtaact gacttaagtg gagggcaaag aacaaaagta cttcttacta aacttctact
    33001 tgaaaatcca actattctta tattggatga gcctacaaac tatttagacg aagagcatat
    33061 aacatggctt actaagtacc ttcaagagta tgagaatagt tttgtcttag tttctcatga
    33121 tattgaattt ataaataata catgtaatgt aatatatcat atggaaaatg gagagttaaa
    33181 tagatataaa ggaaattatg atgaatttgt aagacttaat gatataaaga aacgtcaaga
    33241 agaacaagct tatgataaac aagttgaaga aagaaaaaga ctagaggatt ttgtagctag
    33301 aaataaagct agagtagcaa ctagaggaat ggctaacagt agacaaaagc aacttgataa
    33361 gatggaaata ttagaaagac caaaagaaaa aataaaacct acttttgctt ttaaagatgc
    33421 tagagcagct agtaaaataa tttttgaaac agaagattta gttttagggt atgatgaagc
    33481 attgacaaaa ccacttaatt tccatttaga aagaggaaaa aagattgcct taaaaggaat
    33541 gaatggtatt ggaaaatcta ctctattaaa aactttactt ggaataataa aaccatttga
    33601 aggaaatgtt aaattaggtg actatttgga agttggatat tttgaacaag agagttcaag
    33661 agaaaatagt aatacaccta tggatgaagt ttggagtgaa tttccagggc ttacaaactt
    33721 tgaagttaga caggctcttg caaaatgtgg acttacaaat gaacatataa cgagtcaaat
    33781 gagagtatta agtggtggag aagctgctaa ggttagactt tgcaaagtaa tgttaaaaaa
    33841 tataaatttc ttagtattag atgagcccac aaatcattta gatgttgagg caaaagatga
    33901 attgaagaag gctatcaaag agtttaaggg aacagttctt ttagtatgtc atgagccaga
    33961 attttattca gaaattgttg atgatgtatg gaatatagaa gattttacaa ctaaaatcgt
    34021 gtagtgattt aacttattgc tggggggatt tcatgaaaaa gtttctaaat gtactttttt
    34081 cagtttgtat tagtattgtt ataatagtag gtgttattaa ttttactgtt ggatttaaac
    34141 aactttatta ttttgacatt gattacttaa atatatcaga gttatctggt ttatctaaag
    34201 atgatataaa attgaactac gattatctaa ttgattataa cttaaataag aatgtgtctg
    34261 agttcaaatt accaacatta aaatcttctc cacaagggaa gatacatttt gaagaagtca
    34321 ggaatatatt tcaaaatata aataaattag ctaaattatt attggtagtt tctttagtag
    34381 gaattatatt gagtgtaaaa aataaaaata taaaaatctt aaaaactaca tcaataacac
    34441 ttataattat gccattatta ttaacagttc caattttatt aaattttgaa aagtcattta
    34501 ttatttttca taaattatta tttagaaatg attattggat atttaatccc gatttagacc
    34561 cagttataaa tatattgcca gaggaatttt tttttcactc tggaatgatg attttaatat
    34621 taattttgtt agtaagtata ttactgtttg taatgtataa attatgtaaa tctttatcaa
    34681 taaaaatatt tcaatgttaa atagagggat atttttattt ccaaaataag ataataaaaa
    34741 aggattagat taaaagttat acaataaaaa tagctgtgca ataatattta gactatgaaa
    34801 gtagttaaaa aatatttatg tacagctatt tataatagaa tttacttttt actagtgatt
    34861 ttaactaaat cttgaaattt actcataatg taattgtaat tatctttttt gtgaggtaac
    34921 atgcaactac tgcaatcttt gataccttta tctgtatact taaagtttcc accacagttt
    34981 tctcctaaag catacaaagg acaatagcaa aatagacagt taaactcttc tggtttatta
    35041 gttttatgac aagggaaaaa ttcgcaatct ttgtgattaa aaaacttata attttcgccc
    35101 atattttcct cctaattaaa taaaatttaa attttttata ctatataaga ttttggtgat
    35161 aatataatta tactaaataa ttttatgaat agtcgataat atagtattat taatcatagt
    35221 attaatggta taattagtca acagaaaaat aatgtaaaaa taatgtaagt gtattttgta
    35281 attagaatat gttttataac aaaaaatgag gtgattaagt gaaagaaatt caagaaaaag
    35341 cacttcttgt aggtctgaat ttgactacaa tagtgaaaaa aaatgatgat atagacacta
    35401 atgaatctat ggaagaatta aaagaactaa caaaagctgc tggggcagaa gttgtaggta
    35461 gcttaattca aaataaacac tctgtagatg cagcttatta tataggaaaa ggtaaagtag
    35521 aagaaataag agcctatagt gactctttag atgctacttt agtaattttt aatgatgaat
    35581 tatctggtgc tcaaatcaga aatatagaga atgttgttgg aagaaaagta atagatagaa
    35641 ctactttaat tttagatata tttgctcaaa gggcacttag caaagaaggt aaattacaag
    35701 ttgaattagc acaattaaaa tatagattgc cacgacttta tggaatgggt ggtgagatga
    35761 gtagaacagg tgcagggatt ggtactagag gtcctggaga acaaaaacta gaaatagata
    35821 agagacatat acttaataaa gcagcagata taagacgtga acttaaagaa gtaaaaaaga
    35881 atagagagac acagagagtt aagcgtttaa agtcaaatat accgattgta gcacttgttg
    35941 ggtatacaaa tgcaggaaaa tctaccctgt tgaacgaatt aataaagaca cacaaggatt
    36001 atgaacaaga aaaagaagtt tttgtaaaag atatgctttt tgcaacttta gatgtaactt
    36061 tgagaaaggc tcttttgccg aataaaaaag aatttttagt agtagatact gttggatttg
    36121 taagtaaact tccccatgat ttagtagaag cgtttaaggc aacattggaa gaagtacagt
    36181 atgcagattt aatcttacat gtaattgatg caacaaatac tagttatgaa ttgcaaaaaa
    36241 gtacgactga aggtgtatta aaagaacttg gtgtaaatga taaaaaacat atacttgtat
    36301 ataataaagt ggacaagcta gaattggata tatatcctaa aagtcaagaa gatattgtgt
    36361 atatttctgc aaaacaaggc ataaatatgg ataagttatt aaatatgata gaaattgctt
    36421 taatggaaaa tacttattca gtaagtttga tgttacctta tgagagaggt gatatattta
    36481 gtagaataaa agataaatat aatgtggaga attttgagta tggggaaagt ggtataacgc
    36541 tagatgtaga tttagatgaa gaagatttta atatctatag agagtacata ctagaaaaat
    36601 aggttgaata tggatataaa ctgggaaaat atagataatc ttgaagatta ttttataacc
    36661 tatcttcttt ataaagaatc taaaacagta tctcaaatta gtaaaattag aaatatttca
    36721 agtactgaag caagtgagca acttatacaa gcaaagttaa aaataaagga aatgcaaaaa
    36781 gatgattttg aggcatctaa ggatattttg gataaatttc tagaactaga taaaattaag
    36841 agacttgatt ttatggatag cttagatgac gaaaaaatgg tatactttaa gagaaaggtt
    36901 ttcaaaagaa tccttgtaga aaaaaatgct gaagatttaa ttgttttaat ttgggcgaca
    36961 ggtgagctaa aagatgatag gtttttgaaa ttgcttcatc agctcacaaa ccacagacac
    37021 tcagatatta gaagaataac ttattcagca atcagaaaga ttgaatcacc aagtagtaga
    37081 gaagtactgc aaaaaggtct ctacgacaaa aatgcacaga ctaggcagta ctgtgcaaaa
    37141 gctctttcaa aattgggaga tgaaaacagt ttaaagattt tacagcagtt gaaagacaag
    37201 aataagaatt ttgaaaaaga atatgtgctt agagcttatg acgaagccat taagtcattg
    37261 gaaaatgcaa aaaatttgaa aaagtaattt tttattaaag caatttgttt acttaatgat
    37321 gtatttctaa agtttaacaa ggtaataaat aaattaatgg gaggggtttc aaatgatagt
    37381 aagacgttgt gcaggtggag tagtgtttta tgctaataaa gtacttattg taaaaaatga
    37441 taggggtgaa tggacacttc caaaaggaaa gatactagga gggggacttc catatgagag
    37501 tgctgttcaa agagttaaag tagaaactgg catagatgct aaaatgatag atgtggctgg
    37561 cgatactatg tatgaatttt tctcaagaag tagacaacaa gaagtttgta atgcaataat
    37621 gtggtatgtt atggaagctt gtaacactga ttgtgtactt gctcctgaat ttcaagaagg
    37681 tggattttat aaagtaaagg atgctttaga aatgttatca catcataaag agcaagcttt
    37741 agtagaagta tcttataaaa agtttaagga attaaagaaa ttagtttcag agggcgatga
    37801 tgttccagca aattaattgt gaatttagag gattctgagg aagggatagc cccttccttt
    37861 tttaattgaa gcagttttaa gcgtaaatta tatagtctct ttaaactatg atttatcaat
    37921 ttagagattt agtagtttat atttaaaatc agtaagatat atttaaaata aaaattaaaa
    37981 agtatacaat tttattatat aattgtctta tgatgttgat taaagaatta ttaaaagtcc
    38041 atttattttt aaatagaata attttataaa tatatatttg atgtgtatat tagaaaatga
    38101 ttaaaatagg aggaaataca atgagcaatt acaggacatt acatgaattt ggaacggatg
    38161 aaataacgat tgaaaagtct gtttttattg gatatgctaa gcctataaag agtgaagaag
    38221 aagcattaga gtttataaat gaaataaaga aaaagcataa agatgcaact cacaatgtgt
    38281 gggcttatac tgtaggtaaa aatatgaata tacaaagata tagtgatgat ggagaaccac
    38341 aaggaacagc tgggatacct acattagagg ttataaaaaa agaagatttg agagatgtag
    38401 cggttgttgt tactaggtat tttggaggaa caaaattagg tgcaggtggt ctagttagag
    38461 cttatacaaa aggtgctaaa ctgggacttg aagcaggtaa gataatttat aaggtaatgt
    38521 atcaagaagt taaggttaag atagattata ctcaacttgg aaaagtgcaa aatgagttaa
    38581 tgaatttggg gtattttata aaagatactg tatatgagga taatgttgaa atagtagtat
    38641 attcaagatt agaagatgta gagaaattat cagaaaaaat gattgatata acaagtggaa
    38701 caggaaaaat agttttagga gaggaatttt atttgtctga acaaaatgga gaaattttaa
    38761 tataatctaa aaggttatta gaatagttaa tacctcaaat agccaattag tatttttaag
    38821 tgaaaagcca ttaaattgat ttaatctaaa tcaatttaat ggctttttat cggattttgc
    38881 acagaatcct ttttttactt caaataaacc gactaaaagt aaaaatatcc caaatatttt
    38941 ttttaatata tctgaagaca gataattagc taatagtgaa ccaaatacag ctcctaaaac
    39001 cccaaacaca gctataggta taaccaattt aaaaattaca tttttatttt ttatatgtat
    39061 agcaagtgct ataagtgtca tagggataga tgaaagtaaa tttacgcttt gtgctatttt
    39121 agtgtctatg ccagcaagta aaacgagtgc aggtataagg attgttcctc cacccattcc
    39181 cattcctcca ataattcctg caaaaaatcc aattagagca aataacatta aaacaccatc
    39241 cttaatgctg caattatcat aattattcca aaagaaattc taagaaattt tccagtaacc
    39301 ttatttagta atttagctcc tataatacca ccaagaatac ttccaactgc aactttaatt
    39361 gttaagttaa catcataagt acctttagat acatataaaa cagaacttgc tgtcgttaag
    39421 aatattatta tagaaagagc agttgcatga gatttatgtt cttctacctt aacgatgtca
    39481 tttaatattg gaactaaaag agtacctcct ccagaaccaa aaactccatt tataaatcct
    39541 gtaaaaactc caattatcgt attttttaag ttaaaatcaa agtatttttt ctttaaatca
    39601 tcagtttttt tcataaaaat caccttctga aatagtttta ccaaaatagg caaattatat
    39661 ttatataaaa taagattaaa tataatcttt catgtttgtt taattttgca taaaaaaaaa
    39721 catattaaaa caacatatta atatatggta taatatatta aaacaaagta gcaaatttga
    39781 gaggagataa caatgtcaaa tataaaaata caaatagaca aaactgtaga atggcttata
    39841 aataaggtta atgaggcaaa tgcaaaagga ttaattgttg gtgtatctgg aggaattgat
    39901 tcggcagtag ttgctaattt aattaaaaag gcatttccag aaaactctat gggagttata
    39961 atgagcataa aaagtaatcc tcaagataga gaagatgcac ttaaggttat agagggatgt
    40021 gatatagaat accttgattt agaccttata gaaccacaaa gtgctatatt agacatggta
    40081 gtaggaaatt taaaagataa acatttatat agagaagaat atttaaagat gacagatgca
    40141 aacttaagag caagagtaag aatgagtaca atttatacaa ttgctaacaa tctaggatat
    40201 ctggttgttg gtacagacaa tgctgcagaa atacacacag gatattttac taaatttggt
    40261 gatggtggag ttgatatttt acctattgca aatttaacta aaggagaggt gtatgaatgg
    40321 gcaaaagagc ttggtgttca tgaagattta ataaacaaag ctccttcagc aggtctttgg
    40381 gaaggtcaaa cagatgaaga tgaaatggga actacttaca atatgataga tgctgtgtta
    40441 gaaggtagat tggatgaagt tcctaaaaga gaccaagaga taattgaaag acttcataga
    40501 ttaagtgaac acaagagaaa aacgcctgca caacctccta agttctaatt tactatttat
    40561 aagatttgtg ataaaattta caagtgatga aaattagaat aattaattgt acgtattaag
    40621 gagtggaaat atgggacgta taggtaatat aattaataga aaaggtaaac aagatgctca
    40681 aagagcaaag atatttacta aacatgctag agcaatagca gttgcagcta aagaaggtgg
    40741 agcagaccca gagtacaatg cagcgttaaa aacagctata gaaaaagcta aggcagataa
    40801 tatgccaaat gataatatag atagagctat cgctaaaggt gctggagcag gtgctggaga
    40861 agactatgaa actatagttt atgaaggata tggacctggt ggagttgctg ttatagtaga
    40921 aactttaact gacaacaaaa acagaactgc tggtaacgta agatactatt ttgacaaaaa
    40981 cggaggaaac ttaggaacta gtggatgtgt gtcttttatg tttgataaaa aaggacaaat
    41041 attagttggt ttaggagatg gagtttcaga agaagaattg atggatgttg cattagaagc
    41101 aggagctgaa gatttcataa cagaagaaga tggttatgaa ataataacta caccagaaga
    41161 tttttctagt gttcgtgatg agttaaaagc taaaggatat gagtttatat ctgctgatgt
    41221 gaagatgata cctcaaacta caactgtatt gactgaagaa tctcacttaa aaatgatgaa
    41281 taaattagtt gatatgcttg aagaagatga tgatgttcaa gatatatatc ataactggga
    41341 agtagaataa atagtataag catattgaaa tttataagta tttaatcaat tttaacatgt
    41401 gataaatttt atagaataag aaacactaaa atagacatac gcacctctaa cctatatttg
    41461 cataataata tgtaagcata ggtaaggggt gtttttatat ttataggtta agaaatttaa
    41521 agtaaatttt gagctggact cgattgtcta taaataattg atgggtatat aacttgttgc
    41581 tgaataccat ttatacgccc agttactgta tcaataatca tcctaagact acgttctgct
    41641 gtctcttcca tttttaaatc tataactgtc aaaggaggaa tacttcttgc cattagtcgt
    41701 gaaggtccat tacttgctgc aaatatttga atatcctctc caattacaat tcccgattca
    41761 tgaaatgcat tcatcatacc aagagctacc acatcatgat tacaaaaaat tacttttttt
    41821 agtgaatttt ttgcaagcat tttttgagca atatcatatc cactatctat tttattagaa
    41881 caataatata tagaatctga tagatgtatt ccatgttctt tacatgtttt taaaaaagat
    41941 ttacccctta aagtcataca tgtaaaggaa gttgggttga atacaacagc aatatcattt
    42001 ttaccatttt gaatagcatg taaagcggct atacgaccag tttcctcatt atcaatagat
    42061 acacttgaaa aaccaggtat ttcacgattt acaacaacta caggaatttt aggtttattt
    42121 tttactagat attctatatc atcagcattg atacctgtta aaacaattcc atcataataa
    42181 ttatttgcaa aaaagtattc atcatcacat agatgaccaa ctttgtaagg tcgtatgatg
    42241 atatttatgt ttaaatgttc taaagaaatt atgtggttta ttgcttgaag tatattggtt
    42301 gatgccaact caaatccctc atcctgccaa taaaaagcta ttttaatatt attatgttta
    42361 ataggagtag agcgtttata tccaagctta tcagctgaat ttaatataaa ctcttgtgta
    42421 tgtagcggaa tcctgcgttc atttccttta ccacttaaga cgtacgagac agttgctgaa
    42481 gaaagaccac agtcttttgc aatatctttg attgttgcca tgataaaatc ctccttaaat
    42541 agttgcttaa atttgcttat accaataatc ttaacatata ttcaactaaa gaacaatatt
    42601 ctacaaggtg catattttac aggattagaa taaataaatt taaaaaaact tcttacttat
    42661 gttgacataa tttagtttat aggattataa tatgcttaaa taagcttatt attaacttga
    42721 attaagcaaa gttaagcagg aacatgcaat gctagcttgc aatgtgactg taaaggggga
    42781 aaaggtatga gtaaggtaaa tatatttgaa gttggtccta gagatggatt tcaaaacctg
    42841 aaagagtttt tagaaactga taaaaagctt aagattattg atggtcttat tgcttcaggg
    42901 attaaacaac ttgaaattag ttcatttgta agcccaaaag caatacctca gatgaaagat
    42961 gcaaaagaag tagcaactta ttgtgtagaa aaatatcctg atgtgaaact ttatgcatta
    43021 gttccaaatt tatacggtgc taaagttgca tgggagtgtg gtataagaga tatatcctat
    43081 gttatatctt tgagtgaaac tcataataaa aaaaatataa atcgtaccca tgaagagtct
    43141 attgatgagc ttaaaaaaat aatgaatact tatccagaca tgaatatatg tattggaatg
    43201 gctactgtat ttggatgtcc ttttgaaggt ttaccaaaaa ttgaagatgc cataagattt
    43261 gctaaacgcc tttgggaaaa cggtatcagg gagatgaatc tagcagatac aatagggatt
    43321 gctgacccta agcaagtaag agaaactatt agtgcattag ttgaagcttt accagagtgc
    43381 agatggcagg tacatattca tgatactaga aatatgggaa tggttaatac tcttgtggct
    43441 attgaatctg gaattactac tgttcagtct acacttggag gattaggagg atgcccattt
    43501 gctcctggag catctggcaa tactgcaact gaagatttag tatatatgct tgaacgtatg
    43561 gggtatgata caggagttga ttttgttaaa cttcttgaat tatcaaagta tcagaagagt
    43621 tttgtaaatg gagtatatag tggtcatcat gtaaatataa agtctgatag ttgtaattgt
    43681 tagttctatt gattaatcga ttaaaaaaat atgttgatta aaaaaatatg ctgattggta
    43741 aaatagattt attgataaaa aatataaatt ataaaataca ttatctaata aaacaaataa
    43801 aaaaattgag ggggattagt atggatatta tagctttact tttattttta ggagttatta
    43861 ttattgcatt tgtacgtaag aataatgcag gtattttggc tctagctatt ggtgtcatag
    43921 ctgttagaat ttttggaatg gatgataaag aactttatgg agctataagc aactcaatgt
    43981 ttactacact tgttggtata acactactct ttgcaatagt gaactcaaca ggagcattaa
    44041 agcttgttgc agaaaaaatt gtagctgctt ctggtaaacg tgtttggctt atacctatag
    44101 cagtttttat agcaggattt gttgttgctg gtgttggacc tggggcaatt ccagcacttg
    44161 caattatccc agcaatggct gttcctgtag ccataacggt tgattataat cctgtaatgc
    44221 ttgcacttat aggtgaatgt ggattaatgg caggtcgtat gactcctatt actccagaag
    44281 gtcaaattat aacaaccgtt gcagaagggg ttggaattga aaatgttatg cctactatct
    44341 tagcctgtca aactctttct acaattgtat tttcaatagt attgtttata attttcaaag
    44401 gatataaact taaaaaacct ataaatgtta tagatagtaa gcaaatagaa aaattcaata
    44461 taaagcagat aatttctcta ataagcatag tagttatgat tgcttttatc ataatttttg
    44521 atatgaatgt tgggcttgca gcttttgcag tttcagctgt acttattttt ttcaatattg
    44581 ctgatgaagg agaatgtatc aaatcaattc catggagcac gatagtaatg gttcttggag
    44641 taggtgcaat gatgacaatc gtagatgcag caggaggtat tgacttgatg agtaatgcat
    44701 tatcatcact gatgaatagt aaaacagcta ctccaattat gagtatttca gcaggactta
    44761 tgtctatggt tagttctgct ttagcagtag tttatccaac tatgatgcct atgtgtgttg
    44821 atatagctaa ggcagttgga ggagtagacc cactagcact tattgctgca gttggtgttg
    44881 gaggttctct tgctggtgta agcccacttt ctactggtgg ggcattgatt ttagcagcta
    44941 tgggttcaag taagaaagac tttaataagg aagaacaaaa taaggttttt gtacagcttt
    45001 tcattatgag tgcagttggc ttattggtta ttgcagtagt atcaatatta tcatttaatg
    45061 caataacaca tttaatgaac taattagaat aactgaaaat aaatcattaa atttaacttt
    45121 taatattaat caatataata taatttggag gggaagttat gaaaaaagga gcattaagca
    45181 atataaaggt acttgacctt acaagagttc ttgcaggtcc atattgtaca atgatgttgg
    45241 cggattttgg agctgatgtt ataaaaatag agatgccaag aaaaggtgat gatacaagag
    45301 gttttggacc ttttgtaaat ggagagagtt tatactatgc aaatataaat agaaataaaa
    45361 aaggtatcac tctaaacctt aaatcagaag aaggaaaaaa tatattttta gaaatggtaa
    45421 aacatgctga tgttgtagta gaaaattaca gaccaggtgt aatggaaaag ttaggtctgg
    45481 gttatgatga gttggctaaa gttaacaatc aaataattta tggagctgta tcaggatttg
    45541 gatgttatgg accatattca gaacgtccag gttatgatat tattgcacag gcaatgggtg
    45601 gtcttatgag tataacaggg caagaaggag gagaaccaac gagagttggt aatgctatgg
    45661 gtgatgtact aggtggaatg aatttaacta ttggtatact cacagcactc aacgctagaa
    45721 aaataatagg aaaaggacaa agagtagatg tttccctcgt tgattctgtt gtatcgtctc
    45781 tcgaaactgg tatacagaga tattttgatt caggacaacc tgaacttatg ggtaatagat
    45841 atgcttcagc ctatccttat gactctttta aggcaagtga tggaagtttt gtaataggct
    45901 gtggtaatga caaacttttt gaaaagttat gtaaaaaagt tctttttaga gaagaccttt
    45961 taatagatga gagatttaaa acaaatctta atcgttgtga acattacaag gctcttaaac
    46021 cagaaataga aaaatggtct gttaagcata caataaaaga agcagttgac ttaatatcag
    46081 aggctggagt tcctgctgct cctatctata atcttgattg tgttacaaca gatgaacata
    46141 tagcaaaagc aagagaaatg attgtagata ttagtcatcc tattatagga aatatgaaag
    46201 tcaatggaaa tccagttaag ttgatgacaa caaaagctaa aattgatatg ccagcaccat
    46261 ctctagggga aagtaacgag gagatttata atggttggct tggttttgat agtgataaaa
    46321 taaaagattt aaaagaaaat ggagttattt gattaaaaaa tagctaaaca cacttgtgac
    46381 tttagtcatg ggaggttcag ttagaataat atcaaaaaat attaaatcaa tactgtaaat
    46441 aaaatataga attgtcagaa gcatttaaga tgggaaaagc tacttagaca ttgagtcttt
    46501 gtggcttttc ctattttcat taagaatttt atattatcag aatagatatg tactaaacta
    46561 aagtattaac aatttaaatt aatagaaaat aaactaccta attatgttga ataaagacta
    46621 ctttagtgaa aataaactta tagagatgct atttaaatta ttttaatgga aatatcaaaa
    46681 atgagactgc attctcaaaa atgagactgc gttttttaag tattttctcg aaaatgagac
    46741 aaaaatattg ttttatgggt tttattgaag aaaaattctt ctgtgaatta caatttaatc
    46801 aattttaaag ttgaaaatta ttaaaaattt agtgaaattt atgtatattt cgtttatttt
    46861 attaaaaata acaatttttt actaaaaata aagaacttca atggtgattg gcatagtact
    46921 tgctatttta tattaacaag aaatgtagaa aaaataacaa tgtataatgg ggggaatatg
    46981 atggaatctg taatggaaaa tttgaacaat cttaaggtgg agcttaagga caaagtctgt
    47041 gttattacta taaatagacc taaagcttta aatgctctta atagtgacac tcttagggaa
    47101 ctatcacaag ttattgatgt agtatcagaa aatgaggcaa tattaggagt tattattact
    47161 ggagaaggta aagtttttgt agctggtgct gatatacgcc agatgcaaaa ctataaaagt
    47221 gaggaaggca gaaaatatgc aggttatgct cagggaattt ttgataaaat tgaagctctt
    47281 gaaaaaacag taatagcagc agttaatgga tatgcattag gtggtggatg tgaacttgct
    47341 atgagttgtg atattagaat tgcatcagaa aaggctatat ttggacaacc tgaagttaat
    47401 ttaggagtta ttccatgttt tggtggaact caaagattat caagacttgt tggaactgga
    47461 atagctaaag agttaatttt tacagggaga caagtaaatg cagaagaagc taaatctatt
    47521 gggcttatta ataaagtggt tccaagtgat ttacttttag aagagtctat gaagatgatg
    47581 aaccaaatag ttgaaaaagc gccaatagca ataagatatg caaaagttgt tattaacaaa
    47641 gggatagata tggatttaaa gaatgctctt gaactagaga aagatattgc aggtttaact
    47701 tttgctacaa gagataagca agaaggaatg aatgcattta tagaaaagag aaagccagtt
    47761 tttgaaaata agtagctatt ataactaaaa ttggaacaat gtagaatata ttcaaaatct
    47821 aaatttcgtg aaaaaataca tatagtttaa ttttaaaagg agttaattta tgaatacggg
    47881 agtaattata agtttagtag ggattatcat agctctatct cttctagttg taatggttat
    47941 gaagggaata aatattttta ttatagcaat tgtatgttca tcattagttg ctataacagg
    48001 aagcctaaat gtgtatgatg cacttaaagt ggattatatg acagggtttg ttggatttct
    48061 tcaggcaaat ttctttattt tcctaacagg tacattaatg ggaaaaataa tggagattac
    48121 tggtggagca aaatctattg ctaagatgat tgtaagatgg attgggaagg ataaagcact
    48181 actttctatt ccaatagctt gtggaatatt agcctatggt ggagtaagtg ttttcgttgt
    48241 aagttttgca gtgtttccga tagctttaga aatttttaaa gaagctgatt tgccacgaag
    48301 atttatacca gcagctttga cttttggatg ctcaactttt gctatggttg caccaggggc
    48361 accacaaatt cagaatattg ttccagcatc aacattaggg acagatatta tggctggagc
    48421 agtaaatggt tttatatcat gtgcagtaat gtttatagtt ggaagtacca ttttgtacaa
    48481 aatggtttca aaagaaaaag ccaatggtgg tcattttata gcacatgaat cagatatatt
    48541 tgatgaagca gaagcaacta attctaagag agaaaatggt cccaatggtg taattgcctt
    48601 aattccattg atagtgtcaa ttttaataat taatgtaaaa gttaatggaa aagcgatagt
    48661 accaattgag gtgggagtat ttattggagc tttattagta tatttattgt taaataaata
    48721 tcaagataat actaaaatag ttggacatgt tggtgatgca tgtaaaacta cagtagtagc
    48781 aatatgtaat acttgtgctg tagttgcatt tggttcagta gtaaaatcag cagttggttt
    48841 tgacttcata gttaatgcta tgactaatat tcctggtcct cctattgcag gggctgcagt
    48901 tggaactaca gttattgcag gtatttgtgg gtcagcttca ggtggactag gaattgcagc
    48961 tccacttctt ggaccagtat ttttagccaa gggtgtttcc gctgcagcat taactaggac
    49021 tatggcaatt tcatcagcag cattagattc acttccacac aatggatata ttgttactgt
    49081 aacaaatggt ctttgtaaag aaacacataa ggatgcctat atgccaatat tctgggtaac
    49141 tgttttaacc ccatttattg gaaccatagt agcagtccta ctgtttacaa tgttcccggg
    49201 attgccataa gagaaaagat aaaaggtata aattatattt tgatattata aaatcaattt
    49261 tcaaaatata tacaataaat ttcatgtttt aatactgtaa atatgtattt aaaataacaa
    49321 attgaccata taaggaggaa ttgaaagtgt taaataaacc attagaggga gttaaggtta
    49381 ttgacctaac gtattttgta gcaggtccag ggacttctaa aatattagct gactggggtg
    49441 ctgacgttat taaggtagag ccaagctttg gagacccagg aagaaagaca ggggcaacaa
    49501 tgacaatgcc aatagatgat tataataatc ctttttacag cacatataat tcaaataaaa
    49561 gaggtttgtc tataaatctt aagagtgaaa ctggaattga aattatggat aagcttttaa
    49621 gcgaagcaaa cgtatttgtt tcaagttata gaacaggagc attaaaaaga ctaggtcttg
    49681 attatgaatc attaagtaaa aagcatccac accttatctg gggtcagata aatggttttg
    49741 gcgattttgg acctgctaag gataatgcag gatttgatac agttgccttt tgggcaagaa
    49801 gtggggctat gcttgatata gcagaaaaag atacaagtcc aataaatcca cctatagcct
    49861 ttggagatgc aacaacttct tgtagtttat ctggaggaat atgtgcagct ttgtaccagc
    49921 aagctaaaac tggaaaagga caaaaagtaa tggcatcttt atttgggcaa gcaatatgga
    49981 atgcatcatc tttattagca tctacacagt ttagtgatga gtatccaaaa actagaaaaa
    50041 atgctatttc accagtaata aattcttatc gttgtaagga tggaaagtgg atattcttaa
    50101 gtattttaga gcatgaaaga tattttgagg cactttgtag attatttgga agagaagact
    50161 taataaaaga agagaaattt gcatcttcag tagaaagtaa gaaaaatgct acagaactta
    50221 ttaatatttt ggatggtgaa tttgcaaagt ttactcaaaa tgagatggtt gaaaaactta
    50281 ctgctgctga tatagctcat gaaaaaattc aacatgttaa tgatgtagtg actgatgaac
    50341 aggctattgc taataactat atatatgaac atacaagtaa aaatggaaat aagacaatgc
    50401 ttgcatctac tccagttaaa tttggaaata ttgaagttaa catgacttgt gatgctccac
    50461 ttataggaga acattcagat gagatattga gagaacttgg atacagtgat tctgatatag
    50521 aagctctaat tgaatctgga attgtaacaa tgaataaaga agcatgtgaa atatgttaat
    50581 aaacatgtga agtatgttaa taaataggag ggaattttat ggattttaga ttaacagaag
    50641 cacaattaat gcttcaaaga gtagcaaaag aatttgcaga gaatgaaata gcaccaatag
    50701 ctgctgaaac agacaaaaca ggtatttttc caagggagct ttttagcaaa atggctaaaa
    50761 taggatttaa tggaattgga acacctgtag agtatagtgg ttctggtggg gcagatatag
    50821 aaaaggtaat tgttgttact gagattgcca aaaaatgtgc agcatctgca gcaatattat
    50881 caatacacac aatatatgct caagctattt tgaaatttgg tactgaggaa caaaagaaaa
    50941 aataccttcc aatgatggct gaaggtgggt gtgtaggtgc ttttgcctta accgaaccta
    51001 atgctggttc agatgctgcg agagctgcaa caactgcaat tattgatgaa gaaactgatg
    51061 aatatgtttt aaatggaact aagtgtttta tttctggtgg aggtcaagca gaatcattaa
    51121 taatatttgc actgacagac ccatcaaagg gaataaaggg aatgtctgct atcattgtcg
    51181 acaaaggtac tccaggtttt tcaataggaa aaattgaaga aaaaatgggt attcatggtt
    51241 cagaaactgc agagttaata tttgataact gtagagttcc aaagtctaac ttattaggaa
    51301 aagaaggcaa aggatttaat atagctatga cttgtttaga tggagcaaga attggagttg
    51361 gagctcaagc tgtaggaatt gctgaagggg ctttagaaga aagtatcaaa tattctaaag
    51421 aaagagtcca gtttggcaag ccaatttcag ctttgcaagg tattcaatgg tatatagcag
    51481 atatggcgac aatggtggaa tcagcaaaat tattagtata ttatgctgca gatttgaaag
    51541 ctagaggaga aaaacacact aaagaagctg ctatggcaaa atacaatgcg tcacgtactg
    51601 caagagaggt tacaaattta gcccttcaaa tccatggtgg atatggatat atgaaggatt
    51661 atccattaga gagaatgtac agagatgcca aaataacaga aatttacgaa ggtacttcag
    51721 aaatacacaa agttgttatt tcaagagcag tactaggata ggaggaaaag aatgaatata
    51781 gttgtttgct taaagcaagt tccagatact aatgaagtta aaataaataa agagacaggt
    51841 actctaataa gagatggtgt accaagtata atcaatccag atgatagaaa tgctttagaa
    51901 gaagctctaa aaatgaaaga tgaactagga gcagtgatta aggttataag catgggacct
    51961 cctcaagcta aaagtgcttt aaaagaagct ttggcaatgg gagctgatga agcttattta
    52021 atctcagata gagcttttgg tggttcagat acttgggcta catctacaat tattgctgct
    52081 gctatagaga aggttggaaa gtatgatgta atattctgcg gaagacaagc tatagatgga
    52141 gatacagctc aggttggacc agaggttgca gaatttttag ggataccaca agttacttat
    52201 gcgaaagaag taaaggttca agatgacaaa ttactagtaa ctcgttatac agagacaggg
    52261 gattatttaa tagaagcaaa gatgccagtt ttattaactg ctataaaaga gttaaacaat
    52321 ccaagatatc caagtgtcaa aggaatctta gaagcttata ataatggaga tgcaaagatt
    52381 actgtattaa cacttgcaga tttagatgtt gatacaactc aaattggatt aaagggttca
    52441 cctacaaacg tttataagtc ttttgtacca gttaaagaca agcataatga aataatagaa
    52501 ggtataaata aaaaagaaaa agctgagaaa ctaatagaaa tactattcga tttgaaacta
    52561 gtataggagt gttaagatga tgagagcaaa agttaatcaa ggtataaatt taaatgatta
    52621 taatggtgtt tgggtaatag gagagcaaag ggaaggtaaa attaatcctg ttacgataga
    52681 acttattggt gaaggaagaa agcttgctga ccaattagga aaagagcttg cagttgtgat
    52741 agctggatat gaagtagaga aagaagtgaa ggaattactt cactatagtg ttgataaagt
    52801 atattacatc aatgaccctc ttcttaaaga tttcactact gatggatatg caatttcaat
    52861 tgcaaattta attgaaagaa aaaagccaga ggttgtattg gttggtgcta cttctatagg
    52921 aagagatata gcgcctagaa ttgcaggtaa ggttggaaca ggtctaactg ctgactgtac
    52981 aaaacttgaa atagattcaa cagataataa gttattacaa acaagaccag catttggtgg
    53041 aaatttaatg gccactattg tttgtccaaa aaatagacca cagatgtcaa cagttcgtcc
    53101 aggagttatg gcaaaagctg taagaaacga atcagagact ggaattttag aagttgttac
    53161 tccagaactt actgaaaaaa tgattagaac tagattagta gagatacttc cacaagaaaa
    53221 gaaatctgta aatctaactg atgctagaat aatagtatca ggaggaagag gattaaaaag
    53281 agcagaagga tttgagctta taaaagaatt ggctgataaa ttgggggcag agattggtgc
    53341 ttcaagagca gcagtagatt cagggtggat agaacattct catcaagtgg gacaaacagg
    53401 aactactgtt agaccagaac tatacattgc atgtggaata tctggagcaa tacaacattt
    53461 agcaggtatg agtgattcta aatatatagt tgctataaat aaagatgcaa aagcccctat
    53521 ttttagtata tgtgactatg gaatagtagg agatttatat gaaattatac ctgaaatgat
    53581 agaatcatta aataggtaac ttttagaaaa cattgaatat gtagaatgat aagtcttata
    53641 atattgtatt gtaagactta ttatttttgc tgaaggttat agtggggaga tgaaacaatg
    53701 aaagagcagt ggtataagga tatatttgca agagtattat ctatgactga tgatggtttt
    53761 attgttgtaa atacaagtgg agtaataata gatattaatg ataaatattg tgacttttta
    53821 ggaaaagaaa gaaaagatat aataggacaa aatatacaaa gtattatacc aaatacaaaa
    53881 atgctagatg ttatgaaaaa taagtattgt gaagaaggag ctatacatca ttattcaggt
    53941 ggaaatacaa aagaaaaaag tgtaatagta agtaggtctt atgtggaaaa tgacaatgga
    54001 gaagtagttg caggagtagc tcaagttaaa tttagattgc aatcatttga tgtagctaaa
    54061 aagttaatgt cagaatatat ggagctccaa tattataaag agcagtttaa ggataactgt
    54121 ggttttgaca agctcatagg tgaaaataga gacttcatag aacttaagaa aacaggtgtg
    54181 aaagcttcta aaacaaactt tccagtactt ttaacgggtg aaacaggtac aggaaaagaa
    54241 gtctttgcta gagcaattca caataatagc agtaggtcag ataaacctat ggttagtata
    54301 aactgcgctg caataccaga agaattatta gagtcagagc tatttggcta tgacgaagga
    54361 gcttttacag gagcaaaaaa gggtggtaaa aaaggtaagt ttttagttgc gaataatggt
    54421 acaatctttt tagacgagat aggtgacatg cctttgacca tgcaagcaaa acttttaaga
    54481 gttcttcagg aaagtgagat agaaccagtg ggaggtctta aaactataaa gatagatgta
    54541 agagtaatct ctgccacaag aaagaattta agtaaaatgg ttgaagaggg attatttaga
    54601 gaagacctat actatagatt aaatgtaata aacattcata tgatggaatt gaaggacagg
    54661 caagatgata ttttattgct agcaaattat atattaaaca aattaaatgt tgaatacaag
    54721 gaattgaagg ttttaagtga taaggttaaa aattgtttta ttaactatac ttggccggga
    54781 aatataagag aactacaaaa tgtaataaaa agtgcctatg ctgtaagtga tgatatggtc
    54841 attatgatgt gtgaccttcc atctaagatg gataatatca gcagagtagc tcaatgtaat
    54901 gtggatagca attgttcaat tcatgaaatg gttgagaatt atgaaaagag cttaattatt
    54961 gatgtgttaa ggaagtataa ttggaaatgt tctaaggcag cagaggttat gggaatacac
    55021 aagagtcttt tatataagaa aataaaaaag tatgaaattg aattaaataa ttaagataaa
    55081 ttgaattaag gcaatgctaa aaaagcgcct ttattcaaag cgaactgtat aaactgtttt
    55141 atgcagttaa aacgtgtaaa agtagatgtg aagtactaat gtcaatcatt agtacttttt
    55201 tattatattt ataattacta tctatatttc agtatctttt gatatctaag attattatgt
    55261 ttaatttagg atataacaaa accctcttag ttatggacag ttttttatat tttaactgtc
    55321 tactaagagg ggatagttta gtttaaattt agagtaaatt ttatctagca tttataaaaa
    55381 atattttgaa tagctttttt gttatttagt cataattttc tacttcttta tcaagttctt
    55441 tgccacaaga atcacactta tatatagcat tgtatccgta atcatattca tcaactattt
    55501 tcttttgtct aaatacacca ccacactcac ataggaaacc aatttttata agtgtaacga
    55561 taaattgtga ttttataaat tttatatcat tacatttatc gttagtgtaa aatgtataaa
    55621 tataagagtt atcgcactca tctcttaatt caaatctttc aatatatgtg ttatttttta
    55681 attcctcaaa ttcttcttta gttaaatatg atttttgttg caattcatgt aaacgcttaa
    55741 tttggtccat tatttatatc ctcccaataa ttttagtatt ttaagcttag ataaggaatc
    55801 taagttttat taaatttatc ccaaggaatt atttaaatca tatttagttt tattaattac
    55861 aacatatata aattacacga aaataaaact aattgtaaaa ataatatcct gtgaaaacct
    55921 aaactactaa ccccttacta acccgaaaac taaaaaaaga aaatatatcc aaatataagt
    55981 gatatataaa taaagatgtt tcatataaat ttaactttaa atattctgac aataatatat
    56041 ataaatatat tatagttaaa atataccaca tattttgggt attgtatact ggaattagag
    56101 taattaattt attttttaac atacaaatga ttttatgaaa aaaaacaaga ctcaaaaatt
    56161 tttatattct ttgatagaat aaaattgaga gtaaatttat tgaattttat aaaatttata
    56221 aggggtgagt ctaagatatg catgaagata aaaatgatat atttgaatca atagatactg
    56281 aggattttga taataaaaca gaagaagaat gtttagagct agtaagaaaa aatggattga
    56341 atttaatata cataaaaaat caaacagaag agatatgtct agaggctgtt agacaaaatt
    56401 gtaatgcaat aaaatgtgtt cagaatcaga cagaaaaaat atgtatagaa gcagttaaac
    56461 aagattggag aatgttagaa tttgtggaag agccaacaga agaaatttgc atgttggcta
    56521 ttaaccaaga tggaacagca ttaaaatata tagaaaatca gacagaggag ttatgcttaa
    56581 gagccgttga aaaaaatggt gcggctttgg agtatgtaaa agaacaaaca gaagaaatat
    56641 gtatagaagc agttagaaac agcgaatttg gattggcaag agtgaaaaat caaacagaaa
    56701 aaatatgtat ggaagcagtt aagcattgta gctataatct aaaatgggta gaaaatcaaa
    56761 cagaagaaat atgtatggaa gcagtgagac aaaatgggct tgatttgaaa tttgtaaaaa
    56821 atcaaacaga aacaatctgt ttaagagcag tgagacaaaa tggaatggca ttagaatttg
    56881 taaaggaaca gactgttggt atatgcttaa aggcagtaag acaatatgga atggcattaa
    56941 aatttgtaaa agaacaaaca gaagaaattt gtacagaagc tataaaacaa gataaaagag
    57001 cacttagttt tgtaaaagga gataaggaaa aatacaaggc tctatatgat aataatgaac
    57061 catttgcaaa gagatatgtt agaaatgtaa tagaaaaaga aaacagagca ttgattaaaa
    57121 aaggagaaga aaatgcaaaa atcaaaattg caggaaaact ttatgataga ggcatgtctt
    57181 ttgaagatat atcagatata gttgagattg aaataagcaa gttaaaagtg agtttaggtg
    57241 ttttttaaag taataaatgt aggtgttttt tatgggaaat agttaataaa aaaataatcg
    57301 attagctctt tgtaggacag caaaattagt gatataattt gatgtataat aaattatttt
    57361 tattagataa gggggaatta aagttgaaga ttacagtatt ataccaaaca agaagtggaa
    57421 acacagaaag ggtcgctaag ctgatagaag agggcgctaa aaaggtggat ggagtagatg
    57481 taaagcttat gagacttgat aatattgatt tagattattt aaatgaaagt aaagcagtaa
    57541 tatttggaac acctacttat ttagcaaata caacttggga agtaaaaaaa tggtttgatg
    57601 aagattcaaa aaaagttaat ttagctggaa aattaggagc tgtttttgct acatgtgatt
    57661 atatatgtgg aggtccagat gttgcgatac ttactatagt aggacatttg atggttaaag
    57721 gtatgcttgt gtattctgga ggtggttctt taggaaagcc atttatacat ttaggacatg
    57781 tacattcaat tgaaggtcca gagttacaag atgagaaggc tataatattt ggtgaaagaa
    57841 ttgctactaa ggcaaaagaa ctatttgctt aatttctata tgcataataa tgattagagt
    57901 aaatttaggg ttttaaggga gatttgaagt aaaagttata aaataaaaaa ttttccataa
    57961 aattactcaa gatgaattat aatataatta taaataaatt atattattaa aatatttaaa
    58021 atcaaacgtc aatagcgagg gaagtttatg gtatggcata tagaatatga gattttttct
    58081 gcaattatag ttattttttt aatggtatac ttttttagaa gtaaatttat acctacttta
    58141 caaaacaaaa tatattgtgc acttttaata ttctcatttt tatttataat ttcaaatatt
    58201 ttaggttcat tttgtctaaa taatatagac aaaattccaa tttttattac ttttttattg
    58261 aatcagatat acttattgtt attgccaata ccagcagcac ttgtatcatt ttatgttatg
    58321 gctattattt atcaagacat aaggtatatg aaaaaaagat tattattttt atctatacca
    58381 cttataattt gtataatctt atctattaca aatcctttta cgcatattct atttggattg
    58441 tcaaaagaaa caggttatat acgaggttgt ggatatgttg caacttttgc atcttttttc
    58501 ttttatgcaa tatattcagc atttttatct tttaaatata gaaaagcaat gcatgaatca
    58561 aaaatatggg ctattagagg ttttcttata gtttcaattg tggcaattat cttacaggca
    58621 atttttttac agtatcttct tacaggaact gcatgtgcat gtagtttact tttgacatat
    58681 ctttctatgc agaatcgagg tcttattatt gatgacctta ctggtgtact caatagacaa
    58741 tcttttattc aagagctaga tttgaatatc aatactgaac aatcaggatt tattattaca
    58801 attgcgcttg atgattttaa gtttatgaat gaaacttttg gaacaaaaaa tggagatatt
    58861 gcactaaaag aagttggaaa atatttgatt cagatacatg atgtaaacca tgtatataga
    58921 atagggggag atatattttc tattgttgtc aatagtcaat taggtataga accagatgat
    58981 attatcagaa agatagaaga aagatttaaa aagccttggc tagtagaaga gataagtttt
    59041 aatttagcaa ctagtattgc tgttgtttat tacccagaaa atgcagaaac gacagaagat
    59101 gtaattgttg ctatagattt ctctatacat gaagcaaaac gttctgagtc aaggcgagtt
    59161 gtttatgcag atgcgtctat aagtgaaaag ataaagaaga aacatgttat taaaaattgt
    59221 ttaaaagaag cattaaaaaa tgatgggttt gaagtgtact accaacctat attttctaat
    59281 agcaggggca ggtttacttc agcagaggca ttacttaggc tagaacacaa agagttaggt
    59341 tttatacctc ctgatgaatt tattccaatt gcagaacaaa caggattgat taactcaatt
    59401 ggattagtag tctttgagaa ggtatgtaga tttatagcta gtgatgagtt tgaaaattta
    59461 aaattggata atatagctgt gaatctttct gtagtacaat gtatgcaaaa aaacttagct
    59521 gatgatttac tttatcttat gaataaatat aatgtatcac caactaaatt taaacttgaa
    59581 attactgaga ctgtggctat gggctctttt aatataataa aagaaacaat ggaaagatta
    59641 attgatttag gtgttaagtt tgcacttgat gattttggaa ttgcttattc tggagttact
    59701 aatatgcttt ctttaccatt ttcagtaatt aagttagata agagtttgat ttggtctatg
    59761 aatgaagata gtaggcataa acttacagtt gagacgatta tagcacttat aaataaattg
    59821 aatatgaagg ctgtagcaga aggtgttgaa accattaagt gtgctgaaga tttaatagct
    59881 atggagtgtg aatatttgca agggtattat ttttctaaac cagttccaga agatgttttt
    59941 aaaaatttgt tgaaagaaaa tacttttaca agttaacacc ctttattttt ttaattacaa
    60001 ctttgttcat tgacactgcc agcgatatat tataaaatta acacaataat aaatattaaa
    60061 tttattatac atattattaa tattaattaa tggagtaaag atttattata tattttattt
    60121 aattatccta aagtgagaaa ggaagatgtg acatgaataa aaagaaaata ttagtgccaa
    60181 ttgatgggac agaaagaagt atgcattctt tggaatttat aaaaggaata tttaaaaaag
    60241 atgaagttga agtagaaata atgaatgtaa aagaactagt atttattgat ggcatatccc
    60301 tggctgaaga gataaaaaat tctgaaaatt taggaagaag aatcttggat aaagcagcag
    60361 agataatggg agagtatgat gttaaagtac attttacttt tggatatcca ggagatgaga
    60421 taattagaaa agcaaaagaa gataatgtag attttatagt tatgacaaaa tctactaaaa
    60481 aaggtcttac aagaatgata ggttcagtaa cagcaagtgt agttaaacaa gcaaaatgta
    60541 tagtgatgat tgtaccggag tagaattaga aaggtatttg aaatatgaat aaaaagatag
    60601 tagcagtttg tgaaagtgaa agaagtttaa actctcttaa gacagctgca aatgatttag
    60661 gatttgattt agtttatgaa attcaagaaa atgataatat aaaaaatgaa ctttctattt
    60721 atgatataga agatgcatcc atagtgttat ttgttacaag tgattctata gaaagcatag
    60781 agaagattga tagatttata gatagagaat tttatgaagt tgatccaaag tatataatag
    60841 aggatgcaaa atctatagta agtgaaattt taatagactt aaattaatcg tgggtgtcgc
    60901 actaagaata gagcgacgcc tttttatata ttttacacaa gaaataaaga ggttgtatca
    60961 aaatatagat aagactcttt ttcattgttg aaatgatgaa aatatatttg atttcataca
    61021 aaaaagagta cctcataact aaaaagttca ctttgagaca ctccattttt atatgttagt
    61081 tgcatttaag gtaaaatata agtttaatca tgttgaaata actgaattac atcttctaaa
    61141 tgattgtaca ttgatgtata acctaagtaa gagtctttac tatcaaatgc aatcattatc
    61201 ttgttatggt ggctaatcat atccttgaga gaatttctat atttaaaacc gaagtattgg
    61261 ttagaagaaa ctgttttagg tattaactca taatatttta taaaaattgg attatgagaa
    61321 gctaaaatta tctctttgtg aaattgcaag tcagcatcat aacattcttc tatcaaacca
    61381 tgagaaacct tatccaattc ctctattgac tttaggtaag tatattttat tttttgaagt
    61441 tctttagatg tagcatttaa aattgctagt ttagtagctt cactttcgat aagttgtctt
    61501 gctcttaaag attctacata aaattcttgt atgttatgat ttttatagat ttcaccatca
    61561 tcaaataggt caactttttt aaatccttca actataggac ttgaataagg cacagctcta
    61621 agtattcctt ccttacagag tatatttatg gcatttctta caggtattct acttatgtta
    61681 aataggtcag caatctttct ctcacttggt aatttactat taattttaaa agttccattt
    61741 agaatgttta atttaatata atcaataatt ttttcagtgg catttaagct tttcataaaa
    61801 actcctaaac atataatttt tttatgattg tattatatca tagttaagag ttaaatctac
    61861 ttttttataa tatgtataag acaggataga ggccaaaata gctataatag ccaagataaa
    61921 gtatccatat tgtattgaag tatattccga tattttacca actatcattg gaaatacaga
    61981 cattcctata gcataaattg cttgaaaaaa acccattgca gtagatttct gatgttttgg
    62041 tacatttttc atagactcgc tagtaaggta agaaaggagt atacctgtag atatacctgg
    62101 tagtacttgt agtacaaata ttatattaat attttttatt gttggaacta aaaagcaata
    62161 ggctgaaact aaaataaaaa ctaaaggaat ccaaaatttt ggtccatact tagtacaaaa
    62221 tttagtagaa gcaaagccag aagaagcaac agcacacacc atgtaaaata tagaagatag
    62281 acctatgagg gtagaactag aacctaagtt tttaagaatt tgagtagtaa atgacattgt
    62341 tgtagacatt tgaataccct gttgaattaa tgccataaag gaaaaaaata caagtctttt
    62401 atccttgcag atagataaat attttttaat tgatattttt ttaggtattt tttttgaatt
    62461 atgatttttt atatttaagg ctagaatcgt tccaataact gaagacaata cactcatgat
    62521 acataaggct gtcattccta atttttcata aaataaagta ctcataacaa atccaatcaa
    62581 cattcctaga ttgtttacca atattatcgt acttgtagct ttttgttgat gttctgtaga
    62641 aaaaaagttg gtatagtgaa ccatgtaaga aatccaagtt gatgatgata ttccagataa
    62701 aatgttagct ataagaaaac cattgcctcc aggagaaaag actcttataa gagatgctaa
    62761 accagcaaag aaaattccag acagtataaa tattttatgt ttatttatag aatcagcaaa
    62821 tactccaaca ggaagcctta ataaacattg tgagattcca tatgcaccta ttattatacc
    62881 aatcatattt gtagatacat tacatgcact taaatatgga ttttggaaag gtatatatac
    62941 atattgtgaa aaccagaaaa atgtaacaat agaaagtaaa agtaattttt gattagatat
    63001 ttttttcata ttatcctccg tatggtattt ttataatgca aataatatac catttggatt
    63061 ttttaatcaa gtactttctc tattaaaaaa aatttaaata tataattatt atttacaaaa
    63121 aaattatact ttatagttga attaagaaaa cgcttatgat actataaagt taacaaattt
    63181 gaatatataa cagtagacgt gttactggta atgcaggcaa gatcgaatca atttttatag
    63241 attatctata gagtactatg ggtataatct atttatttgg ttcgattttt ttgtttaatt
    63301 ggccataaaa caaaaagcct atagttgaaa atggaggatt ttttatggat tataaaaata
    63361 tagctcaaga aattctacta aatgtaggag gaaaagagaa tgtaaatgaa gtgactcatt
    63421 gtatgacaag acttagattt aaagtcaaaa gcgcttctaa agtgaataag gataaattat
    63481 ctaaaactga aggagtaata actgttgttg agagtatggg tcaaatacaa gttgtaattg
    63541 gaaataaagt aaaaaaagta tatgatgagg tcataaaaat tgtacctcaa tcaaataaca
    63601 taggtaaaaa gaatgaaagt caagaaaagc aaggtataat taattctata ttatcagcag
    63661 tagctggtat atttacacct acaatacctg ctatagcagg ggttggtatg attaaaggta
    63721 ttttatcagt tcttgctatg tattatatga ataaaaatgg agtagatata aaagaaacgc
    63781 aaagctatat tatcttaaat gctatggctg attctatatt ctattttatg cctattatac
    63841 taggatatac tgcggctaaa gtatttaatg caaataaaat aatatctatg gtattaggag
    63901 ctacactttg ttatccaact tttactgctt tgatggcagg tgaagaatct gttagatttt
    63961 taggattggc agtaacaaaa gctacgtata catcatctgt tattccaata attattgcta
    64021 tatgggctct ttcatacatt gaaaaagtat tagaaaagta tatacctgag gtaattaaaa
    64081 taataatggt tccaacttta tcattggttg taatgttacc tgcaacatta tttttatttg
    64141 gaccaatcgg aatttatata ggaaatgtca taaacttttc ttataagtat atttatgaat
    64201 taagcccagc attgtgtgga gcatttgtag gtgggttatg gtgtgtgttg gttatatttg
    64261 gtgctcatag agcattatta ccaataggta taagtgatgt tgctcaaaca ggaagacaaa
    64321 atttattggc atttgcagga gctgcaaact tttcacaagc aggggctgct ctaggagtat
    64381 tctttaaaac taaaaatcaa ggactaaaaa caatttctat gtctgcaact ataacagctt
    64441 tatttggtat aactgaacct gcaatatacg gtgccaatct tagattaaaa aaacctatgg
    64501 tatgtgccgt aatatgtggt gcatttggag gtgcgataat gggaatgggt ggagcttatg
    64561 gtaatgcatt tgcaaaccaa ggtgttttaa ctatacctgt atatgctgaa gcaggtgcat
    64621 taggtttctt aagttatcta ggtggttgtg ctatagcatt ttttggttca gctatttcaa
    64681 cttatctagt tggatttgaa gatttggaag agtcttctaa taaggaaaat tcatctataa
    64741 aagtagaaac gaaggatggt gttattgata taacttcacc tgtagagggc gaatgtatag
    64801 aattgtcaga agtaaaggat gatgtatttg cttcaaaagc tatgggagaa ggtatagctg
    64861 tgttacctac aaaaggagta ataacagccc ctactgattg tgaagtagct tctttatttc
    64921 caacattaca tgcaatagga ttaaaattag ataatggagc agaaatgtta atacatgttg
    64981 gaatcaatac agtagaatta aatggtaaat actttacaaa acatgttaat caaggagatt
    65041 tagtgaaaaa aggtgataaa cttatatcgt ttgatataga taaaataaaa aaggctggtt
    65101 atgatgtaac tacgccagtt atagtaaaca atacatttga ttttggacaa gtaatttctt
    65161 gtaaatctag ttatgtttca accaatgata atataatttc attagtatta gctggtaatt
    65221 aagttaattt gactagagat aagtaaattg atttaaaagg aaataagtaa atcaacaatt
    65281 aaatacatct aaaagtaagt ttattgcaat gaattgttaa agaaaataat taatatggag
    65341 taaatctatt gcaatgaagt aacaaagaaa ataattaata tagagtaagt ttattgtaat
    65401 gaattgttaa agaaaagagt taatatagag taagtttatt gtaatgaatt gttaaagaaa
    65461 ataattaata tagggtaaat ctatctcaat gaaataacaa agaaaagagt taatatagag
    65521 tgaacttatt gcaatgaatc aacaaagaaa ataattaata aaaaggagaa atatttatga
    65581 atacaggatt tccaaaagaa tttttatggg gagcatcatc ttctgcattt caagtggaag
    65641 gagcttggga taaagacaat aaaggaaaaa ccgtagccga ctataattct tttaaaaagt
    65701 ctcatttaca ggcagatact aaagtcgcat cagactttta ccataattat gaagaagata
    65761 ttgaattaat gaaagaatta gggatgaaaa catatcgttt ttcaatttca tgggcaagaa
    65821 taataccaga tggtgaagga gagataaacc agaaaggttt agacttttat aataagataa
    65881 tagacaaact aatagagtgt gatattgagc cattcgtaac tttataccat tttgaccttc
    65941 catttaaatt agtagagaaa tataatggtt gggaaagtag agaaactgtc tatgcttttg
    66001 aaagatttgc taaaatatgc tttaagcatt ttggagatag ggtaaagtat tggcaacctc
    66061 ataatgaaca gaatttaatt gttagagtgg aggagagaat taatatatat gatgaaacag
    66121 attcatggaa gatagacaaa atgcgtgctc agatggatta taatctttgc ttagcacatg
    66181 cattagcagt caatgcatgt catgagatga taaaagaaag taaaattgga gcagcagtat
    66241 catcatctgt aacatatcct cttacttcta agccagaaga tgtatatgca gctagaatga
    66301 atgataattt taaagtgtac tatatgcttg atatgcatca ttatggagaa tatccagggt
    66361 attatatgaa gtatcttgaa aaaagaaata tagttcctca catggaagat ggggataaag
    66421 agatacttaa aaaagctaaa atggatttta tagctgtaaa ttattatagg acaaattgtg
    66481 cagaagcttt acctgaagat tcacaacatc catttggatt aagagaagga actgttgatt
    66541 ttagtatgta tggactattt aaaatgtcaa tgaatcctaa cttagaggct tctgagtatg
    66601 gagcagcaat agacccatca ggtcttagag ttgccttaaa tgaatattgg caaagatatc
    66661 acttacctgt tataa
//
LOCUS       DAGQVA010000013        63918 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.013, whole genome shotgun sequence.
ACCESSION   DAGQVA010000013 DAGQVA010000000
VERSION     DAGQVA010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 63918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63918
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.013"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..141
                     /locus_tag="MIV85_000976"
     CDS             <1..141
                     /locus_tag="MIV85_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBY2960344.1"
                     /translation="KVVRLNPGDSTFIKANVPHKIINPSKDTIARGYGVISPPIWPIK
                     SK"
     gene            complement(336..1322)
                     /locus_tag="MIV85_000977"
     CDS             complement(336..1322)
                     /locus_tag="MIV85_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBY2960345.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(1352..2047)
                     /gene="pxpB"
                     /locus_tag="MIV85_000978"
     CDS             complement(1352..2047)
                     /gene="pxpB"
                     /locus_tag="MIV85_000978"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBY2960346.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(2067..3287)
                     /locus_tag="MIV85_000979"
     CDS             complement(2067..3287)
                     /locus_tag="MIV85_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBY2960347.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(3316..4107)
                     /locus_tag="MIV85_000980"
     CDS             complement(3316..4107)
                     /locus_tag="MIV85_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBY2960348.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            4695..5324
                     /locus_tag="MIV85_000981"
     CDS             4695..5324
                     /locus_tag="MIV85_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2960349.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRSVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(5438..6952)
                     /gene="glpK"
                     /locus_tag="MIV85_000982"
     CDS             complement(5438..6952)
                     /gene="glpK"
                     /locus_tag="MIV85_000982"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBY2960350.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            7196..7738
                     /locus_tag="MIV85_000983"
     CDS             7196..7738
                     /locus_tag="MIV85_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2960351.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            7752..10244
                     /locus_tag="MIV85_000984"
     CDS             7752..10244
                     /locus_tag="MIV85_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2960352.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            10665..11063
                     /locus_tag="MIV85_000985"
     CDS             10665..11063
                     /locus_tag="MIV85_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2960353.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(11280..11489)
                     /locus_tag="MIV85_000986"
     CDS             complement(11280..11489)
                     /locus_tag="MIV85_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960354.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(11521..11730)
                     /locus_tag="MIV85_000987"
     CDS             complement(11521..11730)
                     /locus_tag="MIV85_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960355.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            12029..12448
                     /locus_tag="MIV85_000988"
     CDS             12029..12448
                     /locus_tag="MIV85_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960356.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            12676..13131
                     /locus_tag="MIV85_000989"
     CDS             12676..13131
                     /locus_tag="MIV85_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960357.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(13338..13598)
                     /locus_tag="MIV85_000990"
     CDS             complement(13338..13598)
                     /locus_tag="MIV85_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960358.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(13861..14214)
                     /locus_tag="MIV85_000991"
     CDS             complement(13861..14214)
                     /locus_tag="MIV85_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960359.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANVEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(14231..19552)
                     /locus_tag="MIV85_000992"
     CDS             complement(14231..19552)
                     /locus_tag="MIV85_000992"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960360.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTRDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(19569..20552)
                     /locus_tag="MIV85_000993"
     CDS             complement(19569..20552)
                     /locus_tag="MIV85_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBY2960361.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(20553..21251)
                     /locus_tag="MIV85_000994"
     CDS             complement(20553..21251)
                     /locus_tag="MIV85_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBY2960362.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(21248..22300)
                     /locus_tag="MIV85_000995"
     CDS             complement(21248..22300)
                     /locus_tag="MIV85_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBY2960363.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(22293..22721)
                     /locus_tag="MIV85_000996"
     CDS             complement(22293..22721)
                     /locus_tag="MIV85_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBY2960364.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(22721..23047)
                     /locus_tag="MIV85_000997"
     CDS             complement(22721..23047)
                     /locus_tag="MIV85_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBY2960365.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(23063..24592)
                     /locus_tag="MIV85_000998"
     CDS             complement(23063..24592)
                     /locus_tag="MIV85_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBY2960366.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGIIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(24874..25296)
                     /locus_tag="MIV85_000999"
     CDS             complement(24874..25296)
                     /locus_tag="MIV85_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960367.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(25296..27749)
                     /locus_tag="MIV85_001000"
     CDS             complement(25296..27749)
                     /locus_tag="MIV85_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960368.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(27749..27916)
                     /locus_tag="MIV85_001001"
     CDS             complement(27749..27916)
                     /locus_tag="MIV85_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960369.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(27943..28389)
                     /locus_tag="MIV85_001002"
     CDS             complement(27943..28389)
                     /locus_tag="MIV85_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBY2960370.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(28503..28931)
                     /locus_tag="MIV85_001003"
     CDS             complement(28503..28931)
                     /locus_tag="MIV85_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBY2960371.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(28945..30009)
                     /locus_tag="MIV85_001004"
     CDS             complement(28945..30009)
                     /locus_tag="MIV85_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBY2960372.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(30014..30457)
                     /locus_tag="MIV85_001005"
     CDS             complement(30014..30457)
                     /locus_tag="MIV85_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960373.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMKEINLNLGE"
     gene            complement(30706..31146)
                     /locus_tag="MIV85_001006"
     CDS             complement(30706..31146)
                     /locus_tag="MIV85_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960374.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(31251..31448)
                     /locus_tag="MIV85_001007"
     CDS             complement(31251..31448)
                     /locus_tag="MIV85_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960375.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            31617..31937
                     /locus_tag="MIV85_001008"
     CDS             31617..31937
                     /locus_tag="MIV85_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBY2960376.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            32019..32525
                     /locus_tag="MIV85_001009"
     CDS             32019..32525
                     /locus_tag="MIV85_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960377.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            33226..33981
                     /locus_tag="MIV85_001010"
     CDS             33226..33981
                     /locus_tag="MIV85_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBY2960378.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(34124..34552)
                     /locus_tag="MIV85_001011"
     CDS             complement(34124..34552)
                     /locus_tag="MIV85_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBY2960379.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(34973..35173)
                     /locus_tag="MIV85_001012"
     CDS             complement(34973..35173)
                     /locus_tag="MIV85_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBY2960380.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(35356..36525)
                     /locus_tag="MIV85_001013"
     CDS             complement(35356..36525)
                     /locus_tag="MIV85_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBY2960381.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            36761..37582
                     /locus_tag="MIV85_001014"
     CDS             36761..37582
                     /locus_tag="MIV85_001014"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBY2960382.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRHEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(37658..39046)
                     /locus_tag="MIV85_001015"
     CDS             complement(37658..39046)
                     /locus_tag="MIV85_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBY2960383.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGSLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVRNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(39181..39939)
                     /locus_tag="MIV85_001016"
     CDS             complement(39181..39939)
                     /locus_tag="MIV85_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBY2960384.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFASSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(39941..40657)
                     /locus_tag="MIV85_001017"
     CDS             complement(39941..40657)
                     /locus_tag="MIV85_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBY2960385.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(40659..41366)
                     /locus_tag="MIV85_001018"
     CDS             complement(40659..41366)
                     /locus_tag="MIV85_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBY2960386.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGQ"
     gene            complement(41482..42018)
                     /locus_tag="MIV85_001019"
     CDS             complement(41482..42018)
                     /locus_tag="MIV85_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBY2960387.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(42120..43190)
                     /locus_tag="MIV85_001020"
     CDS             complement(42120..43190)
                     /locus_tag="MIV85_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBY2960388.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(43183..44241)
                     /locus_tag="MIV85_001021"
     CDS             complement(43183..44241)
                     /locus_tag="MIV85_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBY2960389.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(44228..44560)
                     /locus_tag="MIV85_001022"
     CDS             complement(44228..44560)
                     /locus_tag="MIV85_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBY2960390.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            44759..45880
                     /locus_tag="MIV85_001023"
     CDS             44759..45880
                     /locus_tag="MIV85_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBY2960391.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(46008..47906)
                     /locus_tag="MIV85_001024"
     CDS             complement(46008..47906)
                     /locus_tag="MIV85_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBY2960392.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            48221..48997
                     /locus_tag="MIV85_001025"
     CDS             48221..48997
                     /locus_tag="MIV85_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBY2960393.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(49089..49841)
                     /gene="xth"
                     /locus_tag="MIV85_001026"
     CDS             complement(49089..49841)
                     /gene="xth"
                     /locus_tag="MIV85_001026"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBY2960394.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(50002..50952)
                     /gene="galT"
                     /locus_tag="MIV85_001027"
     CDS             complement(50002..50952)
                     /gene="galT"
                     /locus_tag="MIV85_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBY2960395.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            51337..52533
                     /locus_tag="MIV85_001028"
     CDS             51337..52533
                     /locus_tag="MIV85_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2960396.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(52645..53985)
                     /locus_tag="MIV85_001029"
     CDS             complement(52645..53985)
                     /locus_tag="MIV85_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBY2960397.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAHNK
                     HQIAIVITENNGAISNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(54124..54876)
                     /locus_tag="MIV85_001030"
     CDS             complement(54124..54876)
                     /locus_tag="MIV85_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2960398.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(55024..56601)
                     /locus_tag="MIV85_001031"
     CDS             complement(55024..56601)
                     /locus_tag="MIV85_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2960399.1"
                     /translation="MKQKMKGFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     MPFLANNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGIIAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYAIVYYNVFKILILRFNLQTPGREEITDINFDLKPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKDNIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(57013..57465)
                     /locus_tag="MIV85_001032"
     CDS             complement(57013..57465)
                     /locus_tag="MIV85_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2960400.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(57776..59221)
                     /locus_tag="MIV85_001033"
     CDS             complement(57776..59221)
                     /locus_tag="MIV85_001033"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBY2960401.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(59365..60273)
                     /locus_tag="MIV85_001034"
     CDS             complement(59365..60273)
                     /locus_tag="MIV85_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBY2960402.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            60530..61354
                     /locus_tag="MIV85_001035"
     CDS             60530..61354
                     /locus_tag="MIV85_001035"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBY2960403.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            61394..61924
                     /gene="lepB"
                     /locus_tag="MIV85_001036"
     CDS             61394..61924
                     /gene="lepB"
                     /locus_tag="MIV85_001036"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBY2960404.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(62006..63787)
                     /locus_tag="MIV85_001037"
     CDS             complement(62006..63787)
                     /locus_tag="MIV85_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBY2960405.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        21232 a        10523 c         7204 g        24959 t
ORIGIN      
        1 aaggtagtta gattaaatcc aggtgactca acatttataa aagctaatgt accacataaa
       61 atcatcaatc caagtaaaga tacaatagct cgtggatatg gagttatatc acctccaatt
      121 tggccaataa aatctaaata aactcaatat gacacaccta ctttttgtag ataatataat
      181 agatttaaat attgctttta ttttaaattt aaaatattta ctcaaactaa aaaaatagct
      241 atttgactaa tctaaaccat cttaattatg gtaaatagta aatagctatt tgtaagttat
      301 attataaatt ataataaaaa ttgtatttgt taaaattaaa ctgctatatc atttaatact
      361 tttgccttta caactcttat atttttcata ctcttgtaga tatcttgaat cttatcttct
      421 tgctctctca atagtctatg tgcttcatat atatctacaa gttcaaattt tactacatca
      481 tttggctttg cttgtgctaa cttatacaaa tctacactta taacgttccc tatcttagta
      541 tagccaccac tagtctgtct atctgataac attataatcg gttttccatg accaggtact
      601 tgtatagctc cataagaaat accatcagat ataatatctg ctccattaag gtgctttata
      661 ctctctccat ctagtctaca acccattcta tctatttcat tcgtaacttt gtatttattt
      721 gataaaaatt tctctacttc accgttagaa aaagcatcaa attgaggacc ttttacaatt
      781 cttagtacga tttctgaact ataagttgga atatattttg aacttaattt tttatttatt
      841 gtaaaatctt tttcctgaat aaaagtattt atataatctc cttttttaag tgctctacct
      901 tcaaatccac caattttagc tcttgtataa gttgacttac ttcccattgc aagtggaaca
      961 tctattccac cagctattga cacataggct ctagcacctg atttcacacc tctaaatgat
     1021 aatacatcac ctggatttat ttgatatgac ctccagtttt gaatttcttt tccatttatt
     1081 ttagccccta aatctccccc agttactgct atttgcgtat attcatcaaa ggtaattgta
     1141 ggacctaaca ttaaaacttc taaagaagcc tcatcttcag aatttcctac taatatattt
     1201 cctactctat gtgcatactc atccattgct ccacatccag atacaccata ttgaccatag
     1261 ccaactctac ctctgtcttg tattaatgtt tggaaacctc ctaattcaac tttgaatccc
     1321 atatatacca ctccctgtac tataacgata tttaaatact taagttattt ttttcgattt
     1381 ctataaattc atctaatgtt attggaacaa attttataaa atctccagct ctaagcaaaa
     1441 tctgttcttc tctattttca tcatataatt ttaaaggtgt cctaccaatt atttgccatc
     1501 caccaggact atcaatagga tatacaccag tctgggaacc tgctattcca acactcccac
     1561 cataaatttt agtccttggc acttctaatc taggtgtagc tattctttca tccataccac
     1621 ctagatatgg aaatccagga gtaaaaccta gcatatatat caagtactct ctgcttgtgt
     1681 gtatttttat aacttcatct acagtgagat tattgtagct tgcaacgttt ttaatatcta
     1741 taccaaaaac ctcatcataa catactggaa tctcatgtat tttaggtttt ggtaatacta
     1801 tactttccaa attatcttct atttttttta aattctcaat caaactatca aaatctattt
     1861 ctaatggatt ataacttatc ataagtgacc tatatgttgg taccatttct gttacaatac
     1921 ctttaagatt cgatatttct attgctctca taaatgaaat tacttttttg tttatatctt
     1981 ctgatatctc atttccaaat tcagcaacca ctgccttatc ccctgatatc aagtatctag
     2041 tttccataaa tgtcacctct tctaaattaa gcaaataaag cacctaggct gctaagagaa
     2101 gttattcctg tatatgcaga tattaaaact actattaatc caaatattaa aagccatgta
     2161 ggatgcttgt aatctccaac aatatctttt cttttagatg ctataagcat aattcctaat
     2221 gtgattggaa gtatcaatcc atttaaagct cctgctaaaa ttaataaagt agctggtttt
     2281 cctataaatg ccattataag tgttgatatt gctataaatg ctattataaa atatttttca
     2341 tatttatcta taaaaggatt tagtgtcttt aagaaagaaa ctgatgtata agcagctcct
     2401 ataactgatg taattgcagc agaccataat acaagtccaa agaatttata tcctattgct
     2461 cctgcactaa atttaaaagc tgaagcagct ggattttctg ggtcaagttg aagacctttt
     2521 gaaaccactg ccagtattgc taaaaataaa agaactctca tcattgtggc aactaatata
     2581 cccaaaagag aagatttagt tatttctttt atattttctt ctcctgttat tccaccgtct
     2641 attaatctat gtcctccagc aaaagttata taacctccaa cacttcctcc aagtagagtt
     2701 attattggga atatcagtcc ttttggattt tctggtttta ccattcttga tactgcctct
     2761 ccaacaggag gatgatttga tattgctaca tatccaacta taattatcat tcctaatgct
     2821 aaaaatttag ttatcttatc gactagagaa tttgaatttt ttgacataaa tacaaatatg
     2881 gctattaatc cacttaatac agttcctaat gtcatattca tattaaacat tacattcata
     2941 ccaagtgcag ctccaccaac atttcctata ttaaaagcta atcctccaag agctactaaa
     3001 aaagctacta aataacctaa tcctggtatt attttatttg ctatatcctg acctctaagt
     3061 cctgatacac caattactct ccatacattt acttgagccc ctataaaaag gattgttgta
     3121 attaaaatta caaatgaaaa attcggtcca aaatcttggg taaattgtgc agtctgagtt
     3181 aaaaaccctg gtccaattgc tgatgttgcc attataaatg cagcccctat aagtgctccg
     3241 acatcttttt tatttttagt tttatctgta atattttttg tactcatatt ttatctcccc
     3301 ctcatgttat cagtcttata ctatgttctc tgacgaacaa acttctatgt tttctaatgg
     3361 acaaacttct atactttcta attcaaaacg ctttcttatt tctttgacaa actctattgc
     3421 ttttggattg tccccatgta cacatataga atctgctttg atatgtataa cttcacctgt
     3481 taaagtttct acagttcctt cttttaccat cctaacaacc ctatctattg catgttttgt
     3541 atcatgtata actgctcctt ctacatttct tggaaccaaa aaaccattat tatcataagc
     3601 tctatctgca aatacttcat ttgcaaacct aagtccaatt tctttagcag aatttatcat
     3661 ttcactatta tatagcccca acagtataat atctttatcg acttcatata tagcttcaca
     3721 aatccccata gctaactctt tatctttagc tgccatattg tataatgctc catgtggttt
     3781 tacatgttgt atattacatc catttgaact tgcaaatgcc attaaagcac ccaattgata
     3841 ttttgtataa tctttagctt cctgctttgt tattttcatc tcacgtcttc caaatcctat
     3901 taaatctaga aaacctggat gtgcgcctat tttcactcca ttttttttag ctagctgtac
     3961 tgttttttcc atatgactag ggtcacctgc atgaaaccca caagctatat tagctgatga
     4021 aatatatttt aaaacttctt catctaaacc aatcttatac gttccaaaac tttctcctaa
     4081 atcactattt aaatctactt tatacaattt atgacccctc cttgctaaca ttttgataga
     4141 ataagtagtt ttaattttta aattttgttt attttatata ttgcatgaaa tattttatca
     4201 cttgtattca attttatttt tgcaactatt ctattgcatt taattaatat aattttacca
     4261 tttaaggaat atttttgcaa ttattttaat tgaacattca tttgtatttc tttttcaaaa
     4321 aatcttttta ccatttttta gttaataatt aattattttc acttaaaata agggctttaa
     4381 cctttatttt taaagtattt ttcattttta atcactttat atgcaagaca gaatcatttt
     4441 tcttcattca tttgtttctt tcatctatat aattatcatt ctttgtaagt aaaatatctt
     4501 tatattttta taattaattc tttatatagt tttaagtata ataaaatcat gtatactaaa
     4561 tgcatgttaa aatattattt taaaacatgc acaatatttg tacatattgt agacatataa
     4621 acctataaat tatacaatag tattgttaag attatatatt tttttaacat aaattttgta
     4681 ttgggggaaa aacaatggat aaaaactata cgatgccaat ataccaaaaa atagcgttgg
     4741 atattgcaaa taaaatatac acgggtgaaa tacaagagga ttcagtacta tttggacgct
     4801 ctgttttggc tggtaaatac aatgtatctc cagaaacgat aagaagatct gtcaaaattt
     4861 tagaggacat tggcgttgtt aaaagcataa agggtaaagg tgttattgta ctatctccag
     4921 acaaagcttc ttcttttata aaaaaatata gagatattac aaatatatca tcatataaat
     4981 caacacttta taatttaata gatactaaat ctaatttaga aaatgaaata ttagatacta
     5041 taaataaaat tttagactat tctaacagac ttgaaataat caatccttta gtgcccgttc
     5101 agttcaccat aaattctaat tgcaaatata ttggtcaaac agctgcacaa actaaatttt
     5161 ggcaaaatac aggtgctaca atagttgcaa ttaaaagagg tgaagaactt ataatatctc
     5221 ctggaccata tattgaattt ttagaaggag acattctctt agtagttggt gaccaacaca
     5281 tttacaattc tataccaatg tttttatatg aaaacgaaaa ataaattata taatttagta
     5341 tgattatata aaaatgcaaa attaacaaca aaaaaagagc ttcatatttt acataaagct
     5401 ctttttaaat tcaaataaat ttaactttga ttaattttta aatatccaat tcatcttctt
     5461 tttcccagct taaagctctc gatacagctt ttttccatcc tttatataat ttacatctct
     5521 tctcttcact catatttgga ttaaactctt tttctactga ccactttgaa gtaatttcat
     5581 ttcttccaat atagaatcca acagacaacc ctgctaaata agcagctcct aaagctgtag
     5641 tttctactat tttgggtcta tctatatcta catttaatat atctgattga aattgcatta
     5701 aaaaattatt attacttgct ccaccatcaa cttttaatga ttttagtttt aattttgaat
     5761 cgttttgcat tgcttctaaa acatcctttg tctgataagc aattgattcc aatgtggctc
     5821 ttactatatg ttcttttttt gctcctcttg taagtcctaa aattgaaccc ctagcataca
     5881 tatcccaata tggagctcca agacctgtaa atgctggcac tacatataca ccattagtat
     5941 cctctaccct atttgcatac atttcactat cttttgcaga ttcaattatc tttaattcat
     6001 ctctaagcca ttgaacagat gctcctccaa taaatatact tccttctaat gcatatgtta
     6061 cttttccatc aactccccaa gcaattgttg taagtaaccc atgcttagat ttaactatgt
     6121 tactgcctgt attcataagt aagaaacaac ccgttccata agtatttttt gcagtacctt
     6181 cttcaacaca attttgacca aataatgctg cttgttggtc tccagcacat cccgcaatag
     6241 gtattttagc tcctgataac atgcgctcat ctgtatgacc ataaacatag ctagaaggtt
     6301 ttactaatgg caacatgctt attggtatgt ccaattctcg taatatatcc tcatcccatt
     6361 ctaaatcatt tatattgtac atcattgttc tagatgcatt tgagtaatct gttacatgta
     6421 cttttccacg agttaaattc catattaacc atgtatctat agttccaaat aataactctc
     6481 cttgttctgc tttttcccta gctccttcta cattatctaa tatccatttt acttttgttg
     6541 ctgaaaagta tgcatctatt aaaagacctg ttttttcttt tattgattct tccaatcctt
     6601 tatttttaag ttcatcacat atttctgacg ttctcctaca ctgccatact attgcgttat
     6661 aaataggttt accagtatac ctactccaaa caaccgtagt ctctctttga ttagttatcc
     6721 ctattgaagc aatttcttct ggtcttatac ctgctgtttc tataacttct ctcattaccc
     6781 cactttgtga cccccatatt tccatagggt catgctctac ccatccagct tttggataaa
     6841 tttgattgaa ctctttttgt gcaattttca ctatttcgcc ttttttatta aatagtatag
     6901 ctcttgaact ggttgttcct tggtctaatg ccattacata cttcttttcc atcaccatat
     6961 tctccttatc atataatatt taatttatta aaaagaaaaa tttaatatca catatttcaa
     7021 taaataatca tacttaagta caaatttaat ataatagata tttagtaaga agacacttat
     7081 tttctatcat atctatataa taatattata cattatagct tacatattga ttaataaatt
     7141 ttaaaggagt ataataaaca gtgttcataa taattttaat aaaagaggtg gtaatatgcc
     7201 aaagatttta gaaaatgtaa aagaagatat attaaaagtg tctcgggata tgattttaga
     7261 agaagattac tcgaatatta gcataaggaa aatagctcaa aggtgtggta taagtgcagg
     7321 tacagtgtat aattacttta attcaaaaca agaaataata gaatatatca caaaatctga
     7381 atgggattta ttgataaggc gaattgaata ctccaataaa aacactgaag attacataaa
     7441 aaaactaaac attattttta ctgaaataag aaattttata aacaaagttc ataatatcca
     7501 atacaatgac tttttaaaca cttttgaaac agagagattt tttgaaatga aaaaacacaa
     7561 agacgacttt catgaacagc tttcaaataa agtatatgaa gctttagaaa aagaaagttt
     7621 ttttaataat gacaaattag tatgcaatat cataataaaa atgttttttt catattcaac
     7681 atatcttcat atagaatttg aagatttaaa accctatatt gaaaaattaa tacattaagg
     7741 tggtgtttac cttgaatcat aatactagta ttaagaacaa ggacagtaat ccaaaaatat
     7801 ttttagtact tacactttat ctattaggta tatttatggg agctattgat actggaatag
     7861 tatcaccagc aagaacgatt atacaaaata gccttggagt aaatgaaaaa acgggaattt
     7921 ggatgattac catatacaca ttaacatacg cttctgtaat tcctatctct ggaaaattag
     7981 cagataaaat aggaagaaaa tatgtgtatc tagttagtat atttctattt ggtagtggtt
     8041 cattaatatg tggattatca tcactatttt ccaatttcta tattttatta attggtcgtg
     8101 ttattcaagc aattggtggt ggtggaatca tgccaattgc tacagcagaa tttggaacta
     8161 ccttcccaga aaacaaaaga ggcatggctt taggtttagt tggggcaaca tatggtattg
     8221 ccaatatttt aggttcaagc attggtagca caattctaag tatatttgga actcaaaatt
     8281 ggaagtggct attttttgta aatcttccaa tttgtttaat catacttatt ggtggagttt
     8341 tctgtattaa aaacaataag tctgaatcta aagaaaaaat agataagctt ggtacattga
     8401 tgttgatatg tataatcgta tcactattat atggtcttat gaatatagac ttttttaatt
     8461 ttaaaaattc tatacaagat atatcagttt atccatattt attgacattt attgtactta
     8521 tacctatttt catatttatt gaaaatagag ctaaagaccc tattttaagc tttgaatatt
     8581 ttttaaatcc gagaatattg atagtactta ttttatcttt aattgttggt attggaatga
     8641 tgggtatggt attcgttcca cagtatgctg aaaatgcatt aaagataaat gctggttctg
     8701 gtggatattt tgtagctata ttgggattat ttgcaggtat tgctgctcct ttaagcggaa
     8761 gacttattga caagtttggg gcaaaaaaaa tactattact aggattttct gtatctatga
     8821 taggctctct ttacctagtt ttaattgctc taaaaaccaa tactgtattt agtgtatgtg
     8881 taagtttaat atttatggga ttaggaatgg gatttactat gggaactcct ctaaactata
     8941 tgatgttatc aaatacaaga ttagaagaat ctaattcagc acttgcaaca ttatccttga
     9001 tacgctcaat tggtacttca atttctccag ctataatgat tggatttata gcacatgcag
     9061 gattatctgt gcaagataat attatggact tagttggaaa gccctcaact cctaaaatag
     9121 ttcaacttga agaacttgaa aacatgatag atgacttaaa atcagaccct gaaatggcaa
     9181 aaaatttaaa aaatgtctct atcccaaata tgaatgatac ttcaaatata aatatggaca
     9241 tgacaggtgg caaacttcca aaatccttac ttaataaagt tcagtcagca gatacaacca
     9301 acattaccaa tataacaaaa gaaatatcaa caacaatgtt tgatgaaaaa gttccatcta
     9361 taattactaa aatacagaaa aatgtacaaa aaggaataga tggaacacaa agtggaataa
     9421 acggtattga agatggtgaa aataaactaa atagtggtat taaaggagtt caaactggta
     9481 ttgacaatat ggtaaaagct agagctggta ttaatcaagg aatagatggt gtaaaaaaag
     9541 gtattgctgg tgttgacaaa ggtataaaag gtatggaaca aggtcttgaa aaacaagatg
     9601 aggccatcaa ggaacttaca actgcttata ataaaatacc tactacagaa aaaactccta
     9661 ctgataacga aaataactca aacgaacaaa accagagtaa taccagtaat tctgaatcag
     9721 atgacactaa gaatgattct acagaaaata agaataacaa ttccagcgag aataaaccaa
     9781 atgtaaatga acaaaaagaa agtttaaatg ctcaaataca gcaactaaaa aagacaagag
     9841 atgacttaaa tacaaagtta caaaaaaata aaactcaaaa gaacgaatta agtaaaaaac
     9901 taagatcaat ggaatctcaa aagaaagagc tacaaagcaa gttaaataat tctataagcc
     9961 aaaagaaaga catggaaaaa agccttgata caatgcaaca gcaaaaaaaa tcactccaag
    10021 cagttttagc aaagacacaa gaggtaaaaa ctgaaatacc aaaggctttt gataaatcaa
    10081 aattggatta tataaattcc atagaaaata atagaacaaa aatagaaaac acactacaat
    10141 ctactctaaa ctcaggattt aaacagatgt atataacagt attctgtgta aatctactag
    10201 catttataat attattgttc tataaagaaa ataaaactag ataaaagagt gttatagtat
    10261 tatattgtaa atttatctta ttcttaaata ttttattcta aagaataaat tcataaaatt
    10321 tttgtaattg attaatataa attacaatat aatactattt ttctcttaat ctttttctct
    10381 tttacagaca atcaaaaagc aatcttagtt tatcgaaata aatttataca atctattcat
    10441 acaccccttt acatttatat aacaattaaa cctattgtta tatatacaaa tcaaaataaa
    10501 ccatatattt tcaactataa tatgttaaaa tcatattatg agcatattaa tttaagcaaa
    10561 atgtcattta gactttaatt tagtagtttt atattataaa tttatatatt tttaatttta
    10621 aatgtcattt agacattact cataaaaaga aaggagtgta ttttgtggat actttaggaa
    10681 aaagaattgc ttatttgaga aactccaaaa aacttactca gcgcaaactt atggatattt
    10741 taaaatttga aaacttaggc aagtatgaaa caggagatag aaaacctaat tgtgatatac
    10801 taatgtcaat agctgattat tttaatgtta cgactgactg gcttctctat ggtaaagaga
    10861 aggtaaatgt caatagtagt gtaaaagaag ataaagaaga ttacttacat gttactaatg
    10921 atgaaatgac gatattaaat ctatacagac aactaaacga acgtgataaa ataaaaatag
    10981 aaggaatact tgaacttaag atatctgaat ataaagactt aaaaaagcat tcctctaata
    11041 ataatgaaga taaaatggtt taaacataca taatttgata cgattttaca tcatctatta
    11101 accttctttt tttgtagtat attactaaaa tatggatatt ggattattta aaaacaagta
    11161 tagtctaatt tcaagcacat ttataatatt tagattatct tatccatatt ttagtttaag
    11221 tactttgaaa aatataatac atctctatgt ataacttata ttcctaagaa atgcattact
    11281 catgttttta attcttccaa catctttcta tacacaattg tacatccttc ataattcccc
    11341 tctttaagaa ggattgaaca tgtactagaa tatttagtta aagtatttaa tctttccata
    11401 tttaagcttt ttatattact gagtgctgta ataaaatcat caattgctct acaacactct
    11461 ataaccccat ctgaatccaa tttacacaca agaatattca cctactttat atactattta
    11521 ttaatcatct tctgaatatt ctatattaag taattgataa attgatgatt tatatttttt
    11581 acctgttctt cttccattta aaatagctga caaatagttt tcattaacac ctattttctt
    11641 cgctaattcc ctttgagtca tatttaattc aataagtctt tgcttgactt gcactcccaa
    11701 aaaaggtatc catttttttc gagcatccat ttatcaactt cctttctaag cgatttatat
    11761 ttacttttat attattttag cttacgcacc ccctctattt agtatatatt tttaatatgt
    11821 acacatatta agtatataaa tttatttaat actaaataag attttttgat tactttgtgc
    11881 taaaattagg atgtaaattc gtatcattaa gttaattata aagtcatttt gaccttaagt
    11941 caatggtttt tatgtcattt tgacctttaa tttgaaacta tttacatctt aaaaagtctt
    12001 tttgacatta attgaatgga gagtgtttat ggatacttta ggagaaagaa ttgtttattt
    12061 gagaaaagca aaaaacctta aacaatatga actagaagaa atgttgggct gtgacaactt
    12121 aagtaaattt gagagaaaca ttagaaaacc aaattatgaa atattaaaat ctatagctga
    12181 gatatttaat gtttcagtag actggctatt aaatggagat aatctatcac ataaatcaga
    12241 tttaatttgc gattcctcct caaactatcc acttaatagc ataaactcta atgaaataaa
    12301 gcttttaaac aattttagaa aattaaatga ttatgataaa gctaaaatag aaggtatgat
    12361 tgaattaaaa cttcatgaat atgaaaaaga gaaggattta ggaaaaattg agtataacaa
    12421 aaataaagat gagaaaatag ataaataatt tttatgttgc ttttgatacg attttacatc
    12481 atttctttgt tctaatattt ttatttcatt tattttcttt tttataattt tatgataaaa
    12541 taattagtat attttgcttt acttgaatgt aattatttat acaaaagtca aacataatat
    12601 aaatgtagta aatttttagt ttcaagtaat atctcgttat tataactaaa tatttattaa
    12661 aattaggagg ataaaatggg cttaagagac aaattcgcgc aatcatttgc tagatcaaaa
    12721 actatgagtg gccctgagaa aaaggctaat gaaataatgg gtaaattgct tcttaagaaa
    12781 gctatattac ctatcgtttt aatgttcgtg ataataatcg ctggagctat gcttaaaatc
    12841 aattcttggg ttacacttgg cataaattta gttattgctg ttggtgcttt cttctacata
    12901 agaaattcta gtaaaaagta tcagaacttt aaaccttatg ttggcaattt gattagttta
    12961 gagaaaaaag gtaaaaaaga gtacgttgct attataaaac aaggtaagtt accagttaag
    13021 ttacaaatag cttatggtgg tgaagacctt gaacatgtta agaaaaatca aatggttcaa
    13081 ataagttata atccagatgc taaaatagct attttggtta atagacaata atttaataaa
    13141 aaaaaggagt tgtcttaaaa ttgatttttt ctaatcaaat ttaagctcaa ctcctttttt
    13201 aatttttata tgttattttt attacttttt ttaattaata ttttaaatat taaatccttc
    13261 tcaataaaat agtgaactat ctacaatact actttatctt ttcctaacaa tatataatct
    13321 ggtgctactc tttcatgtta tacaccattt tgtaacatac cttttatatc agtaacatct
    13381 tccttaattt cctctacatc tgttttcatt atacccattt gaacaagtat atttttgttt
    13441 atttcttgtt gttgtgtaga taattctata aaattttcta cagttttttt atacatgtct
    13501 ctatcttctt ttttctcctg catagtattt ttaaataata gagcacatag tatacctatt
    13561 gcccctagac tactcaattc ggttattaat ttatccatta tagcctccta ttgtctaaat
    13621 tttttatact tatagcttta atttttgttg tattcttaca tcatgcaata ttatattttc
    13681 aggattatca atttaatctt ctgtacttta aattgtaggt gtaatttata gattgaataa
    13741 ataataaata tatatacaag ttctaatgta acaaaaaata agtacaaggc ttacttatta
    13801 aagttaagac cttgtacttt acataaaaaa aataactaat acatagttat tctaaattta
    13861 ctattcaact ggtatttcta attctttaca tctaattcta acttgctctc taattactgc
    13921 tggtacttct tctattgttt ttttgcctct taaaattaaa gctacatata cttctaccat
    13981 tccactctca cctccagatt ttcttacact aaaagtgctt atattacttg cttcattgac
    14041 agaactttga tttaacaaca tctcatatat ttctacattt gctataaaat tatttgttat
    14101 atcatcatct tgctttactt gacctatact tatgtctgaa atgtctttat actgcatttc
    14161 tacttttcta ccttgtttga tttgttctat tttattttta tcgaatttaa acaattttca
    14221 cacctccatt ttaagcttgt ggctcgttgt tttcagcatc atatctaaaa atcatagatg
    14281 gacgttttat agctgtccat ttatctcctt tttctactat gattttaggc tgagcacttt
    14341 ttatgttggc ttcttctaat tcatagattt cttggtaact tgagtctgat tttttgattt
    14401 caactagttt catgtctttg aataagtcag atttatttat ttttacttga actttagttt
    14461 tatttattaa ttgatatata ggattgtttt ccatcatatc atcctttaat ccctcattta
    14521 atgttactat taagtcagtg ttattttcag taatgtttat gattgaatat actttattgt
    14581 ttatcattaa aatagaatcc ttttttactt taagccctgt ttctgattta aatataaaca
    14641 tacttgaata taaatcgcct gtaggactac tggctttaat cagtatctta ttttctccta
    14701 atactatttt attttgtggt atctcaaata taatgctatt tatttccaaa ttagtcttag
    14761 tagatattaa ttcatcattt ataaacattt caagtttttc tataacatta ttagggtctt
    14821 gtactacaac tctcacttga gatattgatt tttcaactat ttctatagat gctttacttg
    14881 tatctacttt tgttatcatg tatattgtat catctgaaag ctctatatct aaaatatcat
    14941 ttagatgttc aggaattggt attttagtaa attcatataa atcagtaatt gatatagata
    15001 ttttatacat agatttattt ttaccagtta tccatagact attatcattt ttaattacta
    15061 gtatgtggtc atcattatgt gacttaattt ctttaacatt agttaatact ttagtaaaag
    15121 ttcttattat cttatctttt tcactttctc ctagtccaaa taatccattt gtattgtacc
    15181 cttgagcgta caactctccc tcattagtta aaacaagtgt cattgagtta tatatactta
    15241 tatctttaac agaaggtaat ccagtaacct tttgtaactc tcttacatca ttattgtggc
    15301 caactcccaa ttggtactca gtattctttc catatgacca tagagtatta tctgtcttaa
    15361 taatatagga gtagttatct ccacaagcaa cttttttgac atctgatata tttacttcag
    15421 taagagttaa taattctata tcttcaaggg tttgattaat ttctttatat gaattacttc
    15481 ctattccata taacttgcca tccttagcaa cagccaatga atgtgttttt gatatatcaa
    15541 tatcagatac ctcaaatggc aatattattg aagtatactt aaaattatct ttaaatatgt
    15601 ttttataatt tatatactta ttatttgttt ttatatactt atcattaaac attactagct
    15661 tttcattttt cttattaaaa actattttat ctgatgtgtt atctgtttta aaatatgaat
    15721 gtagggaacc ttcaagagct tcatttttat cattatcata tctatggtga atacctaaat
    15781 gattatatct attatctctt gttgaagaat aaaattttcc atatatatct ttaataaata
    15841 tagtattgta actagaaaat acagtatcaa catctttctt tatagatact ttataatatg
    15901 gaactgacat atccctataa gattcatcag atataccata agtatctcta cctgatgata
    15961 tcaaattgtt attattatct atataaagtg tattattagc tgttacaaaa acatctttaa
    16021 catcttccac actatttgta ttattattat ttgctatact tccatatcca ctaagacctc
    16081 caacaaatag tttattgtca tttgttaaaa tggctgaagt atatccatta actactattt
    16141 tttttgcatt tataatatta ttaattactc gtatcccctt tatatcatta gtctctgttg
    16201 aaaagaatac cctctctttt ttccctgtag tataaatcat attgtcattt gttataaaaa
    16261 atgtagcttc acttcctgct gtcacaacag attttacatt ctcaatattt atttttgtaa
    16321 atgtacttat acttccttca gtaaacccaa aatagccatt tacaagtcca catacatagc
    16381 atgtattatc atttttaaca atgattgata catcattaca tagatataca tctctaacac
    16441 catttatagg tatacgtgta aatatattcc tacttgtagt atcacccaat cctaactgtc
    16501 cttttccatt attacctgct ccatataaaa gaccatcatt agttaataat agagatgtgt
    16561 ttccatatac agctacatat tttacatttt caacatttat tttagtaaat atatttctat
    16621 ttacattatc tcctattcct aactgaccag aattatttaa accaacagca taacaggtat
    16681 tatcattttt tatcgcaaat gcatgtttac tattgtcagt aaatctattt acatttatag
    16741 attttatatt atcaatattt attttagtaa atacctttct atttatctca tctcccactc
    16801 ctaattgacc tacatcattt aaaccaacac tgtaaagcat attattatta gttaataaat
    16861 atgtagactt tgaatggcta tatatttctt gtatattaga agatatttca ctactgctat
    16921 tctttttatt gtaatttatc ttattattta aatttaaact actattaact gatataccat
    16981 gcgtaccctt agagttatat ccacatataa ataagctctt atcagttaat attgcaaatc
    17041 tagttttatc tctacttaaa tcataaggag gtataaatat attttttata tttttcatta
    17101 cctttttata attagtggca ttatatccat cttgtgtatc tgaaacatct agttcttttg
    17161 cactttcaga tatattccca aaaccatata gcgtgttaga agataaatac aatagagctt
    17221 tatataaaaa tatggcttta tcagaggtaa taggacctga atttatatta gatgctgcaa
    17281 tattattaga tgattgattg ttaagataat tccttccata ttgatgtata taagatgaac
    17341 ctccagaaat aagtaaatta tctggattga cattttttaa attacttgac gattccccat
    17401 tatataaata agcaaaagtt gtagaagatg atgattgtgt acatcttgta ggataataat
    17461 tatatatata agaatcaaga tatcctgcat atgaaattcc ctgatattga actctatagc
    17521 ttgaatcagt tggttttgtc catgaagtac catggtatcc agttagaaaa gatccaatgt
    17581 ttgtacaaaa tacagttaca tactcatata tgataatatt attaatttta gtaatattat
    17641 tcgtgcatga aactctacta taacttgacc ctgatatatt tatataatac caatcactta
    17701 ataaacctag atttacatta gatccatcag aagtactaaa acctaacagg taatttgtat
    17761 ttataccagt tgcatatacc tttttttcat caactacaat aaatgttgca ttatatgaac
    17821 tataagcatc agttacatta ctaaggctaa tctcagtata ttgacttatt aatgcattac
    17881 taagtccatt aacataactt gaactctttc cagaagtgta tatttgctta ttattagtta
    17941 caattaatga aaaccagttt gataaatcag tatttataac aacttttttt acattatcta
    18001 tagatatttt cttaaataca tctgaattag aaggaagaac acctgctatt gagttactat
    18061 ttggtccaga ataataacaa gtatcatcat ttttaatgta gaatattcct ccagaaatat
    18121 tttttgatgc tactatagac tttacattag agatacttaa ttttgtcaac tcatttaatt
    18181 gacttggtaa gtcagaaccc attcctttgt atctattatt tcctagacca tatacatctc
    18241 cattccctaa aataaccaga gtacaataag gactaaaaac gacatctctt acagaatgta
    18301 tatctagtgg aagttcaata tcctttattt ccatttcttc ttttaataaa gttaatttat
    18361 cctcagattt aattaaattt atataattac tataactata tttttcacta tccattttct
    18421 taaattctac aatgtgcata tcatcaaaaa acgaacctaa ttgtccataa gtattatctc
    18481 ctgtacaata tgaatcatta tttgaatcaa ttagtatgct atgtgataaa ccaatgaaaa
    18541 tattcttagc tacaatattt tttaaatcta taaatgaatt atctatattc tcagagtaat
    18601 ttgctatacc taactgatat atatcattat ttccagcaac ctttaaagta cctttgttat
    18661 ctataagcat agtgttacca tgaccacatg caatagtttt tatatttact tcttctatct
    18721 tagtaaatag tgatgattga agtgcatttc caaaacattt ttcctttcca caaccatata
    18781 tatcattatt atacgtcatt aacacagtgt gttcagaacc acaagctata gtcttaacat
    18841 cattaataga aactaaacta aataaatctc tattattctt atctcctaaa cctagttgac
    18901 cttgattatt aaaaccagta gaatagcatt tattgtcatt ctttattata aaagctgatt
    18961 tattatatga aaatacagcc tttacattgt caacatctac ttttgtaaat gtatttacat
    19021 ttgcagatgc tccattagtt cctagaccta attgaccata caaattattt ccagcaacat
    19081 ataaagttcc atcattgtat aaaagatatg ttgattgaag tccacatgca atatccttta
    19141 cgccttttat ttctggaacc ttctcaaatg tagaaactgt tttccctact ttttctaatc
    19201 ccaatcccat ttgaccatct gtatttatac ctgcgacaag taattctcca tctgaagtaa
    19261 gtataactgc atgagattct ccacatgcaa cttttttaat attggtagat atatttggta
    19321 ttttcgtaaa taattttctt gttgtattgt cttctcccaa tccaagttga aagttactat
    19381 tatctccaca tccatacaag atattattat tttttagacc aaatgtatag ttacaacatc
    19441 cagtaaaaaa attaataaag tcataattat catacccttc atcaaattca tcaactacca
    19501 tatttttatc gccaaagaaa ttacctcttt gaagtagttt agttcttttc attataaaaa
    19561 cctcctaatt atcttatttc atacgaatat ttatttaaag ttatatctgt ctgaccaatt
    19621 gaatatgccc tattagattt tgtttcaaca aagttattat ccatttcatg tatatatcta
    19681 actctatttg cattaaatgg tagcaccaca ttcttaaatg taacactacc aagttctcca
    19741 gttatacact ttctatttaa atctaactta aggccttcta tagctattat gtttttagca
    19801 ttagttaagg tatcatacca atatccagct tcatctacat ctatttctga ctctaattct
    19861 aagtatatta agatatctaa tactttttca gataatttat tgtaactatt ttttaataca
    19921 gatagttcag tttgtatttg acctcctatt acatcatcaa tagatatatt tttaattttt
    19981 tctactacct catttatagc tcctgataag tttttagctt ctgtagataa gagttcttcg
    20041 ccaattttta cttttatttc ttttatattt ttatcaaact tatcatctaa atcttgaata
    20101 tccttttgag ttacaaaaac caacgtcggg tctacttcta atgtaacatt tgaagtattg
    20161 gacaattgta aaatcatttt tacaaccaaa tctttaatac tgccatcttc agcacgtggc
    20221 ttatacgtct ctggatactt acctatagct attatattat tctcattatc cagaacagca
    20281 gcttctctta tcataaatcc accaactgtt cctggtaaaa tagtctctat aactatccaa
    20341 ttaggatttt tttcatcaat tcttagagaa tttatatttc cttcccaaac tacattcttt
    20401 aaagcagttt gttcctctgt tggctcataa tattctccat tactatctcc aacttgaaac
    20461 ttggttaatc caacaagctc tcctagtgca gttgcatttg ctattttttc tctaccaatt
    20521 ttggttaata ttatataaaa tttttcttcc aattatacca cctccgattt aggataaact
    20581 actacatttt ctacacctgt atcatttgca atagctatat taatcttaca attattttca
    20641 atgcatttaa tgcttaaagg ataaaccttt atttcttctc tacttatcat tccagctcca
    20701 cagtttacaa cagcactaca ttttataatt ggttcaaagt atggatgaac ttttacctct
    20761 tcactacata ccatacctcc accacaatag accatacttt tatctagtat tattggttct
    20821 aaatagtgta ataagtgagc aggttttact ctttcaatca tatcgctaca atctaaaaga
    20881 gttttatagt cacagttatt tgctataaaa ctcaatacga atgtaaattc atcactataa
    20941 acttttatat ctgtttctga ttttgtatat gcctcacata tactttttat aacttcaata
    21001 gtactagtac ctctgcttct cattttagct tttatattgc tacgtcttgt gtcaaaatca
    21061 agttcttttt tttcaatgca gagtatgtct tcccacatat ctaatcccca tgttgcagtg
    21121 tcaacaaata attggttaaa ggtatcatca atatcttctt taagaatatt taattctgta
    21181 tcgtatgcac cttgtatctc ctctacaatg taatttctat caaatgatgg tagtttatca
    21241 attagcttca ttgattttcc acctcactaa aattaacagt tgttacacta ggtattttat
    21301 cttcattaat agttatatta tctgtacttc catttataag taggttactt aaatcgtgta
    21361 caccagtagt atttataagt attcccatta cttttgtata gattatctct cctctaatat
    21421 ctctaaagta tgtatttata ctttctagga aagattcttt tacattgtct aatgtatatc
    21481 catcttctag tttcattact gcacttatac ttatttctat tggtaatggt gtcacaactg
    21541 ttatagttgg tccaataggc ttctcttcat ctatatgttg ctgacacctt tcaattgttt
    21601 ctgtatcaac agcttgatta tttttcccaa atatcaagac cttaactgtt cccggaccat
    21661 cccatcttgg ataaacctta acattataga ctccatctac ttccaaagcc cattcttcat
    21721 agtgagcttt atttccactt gtagcttgat ttctttggat tttataaaat ctttctttta
    21781 gttcttcatc tgtctctata tctgtaccac cttcaaaact tcttgtgtta gtaatctttg
    21841 ttactccaga tatattatca actagtttaa attcacaatt tgtaggtaaa ttatatttct
    21901 taccaacttc cagagcttga actgggctat tgtcaccttc ttcactacca atagttacat
    21961 cttttattac tacaaatagt aaatctctat atgatattat tgtgccatta tttattacag
    22021 tacctttctc tccaataaat tcaacttctc catttgactc tgtacctaac tttctatata
    22081 caccaaattc attgactctt ttatcaagaa actggttata tgtgtcttgt ataaaagcca
    22141 ttttatgcat ctttgaaagt tctagatata tcttcgaaag ttctagatta tttccagata
    22201 ccatgttgtt tagaaaagaa ccttctcctt tataaatatc aagattaata ttttcaagag
    22261 ttctattttt tattacttca tatgtctggt cactatacat ttatttccac ctccccatag
    22321 atagtggata cttttacatt tgcactcaat atgtctctgt taaagttagc actttttacg
    22381 tttacttcta atatatatgg atttattaga agggcctctt ttatgaatct actagcttca
    22441 ctttctgtaa gaccttttgt atatttttgt cctattagtt ctgaaagctc tgtcccatat
    22501 tctaaagagt atatctcatg ttcatatcta tttgtcttta tacacttgta tatccaaact
    22561 tttaaggctt cttttttttc aattatttta aagtcacctt tttctaaaat aggttcatct
    22621 ttttcaaaat cccatgccac ttcacgaaag attggcaatt cttctgtttt aggtaagata
    22681 taatcctctg ggacacctat aaaaggaaat attgtactca ttataagctc accaacttac
    22741 ttacaacagc aaatttttcg cctattctaa acattattac catatcccca gattcaaagt
    22801 tatctataaa aggatttttt acttcatgct ggtgttcttg atttgtttct gtgtcaaatg
    22861 tttctagctg tctatcaatc atccaactat ctatcaaaat atcttctttt tctaatatga
    22921 tgttatttgt ctctattttt aaatctggta atttactttt aatttttcca ataaaaaaag
    22981 aaggttgatt atgatacttt ccttcttctc ttattattcc tataaattca tttattggat
    23041 tagccattat atcaccatcc ttttataata ctctcctagc tgtgttaaaa tctcttctac
    23101 tacttaactt acttatttta actacatcac ctttttgtgg agcatgtaaa aattctccat
    23161 tacctatata taatccaaca tggctgactg gattatgaaa aaatactaaa tctcctgctt
    23221 gaagattttt ttgttctact ttcttgcctt ttttagattg ttgatttgac gttcttggca
    23281 aactaacatt aactttttta aaacaataga ccattaaacc agaacagtca aaactacttg
    23341 gtccatttcc accccattta taaggtttac ctagatgttt ttttgcttct gatattacta
    23401 ttttagcttt atcagataca ttaccagaat aaccaccaat aataattttt ccttttcttc
    23461 ttccaaattt actagcttct tcaacatttc caaataaaat atctatatgg tatgttccat
    23521 tcttttctat agttattgca ggtcctacgt catttacttt atagactcca tcacgaccag
    23581 aaactcctgt aattacctgt atttcatctc catagtttaa taaaggatgt ttatttaaaa
    23641 actcttttgt ataataagtt tgctcatatt taccaaccat aggagcagcg caagtttttt
    23701 tagatgggtc aagttttttc tttctacaat ctgtatctcc accttcttct tttctaggac
    23761 agtaagctgt aaattctgct gtaaactctt ttcctcctgc ataatcttct ccccctaaat
    23821 tactttcttc cttaggttca tcctgtcctg ctgacttttc atccataaga ttttgaaaat
    23881 taagttcaag ctcaatttga tattctccat tttgccaagt atgtttgtct gtatctatat
    23941 aaaatagtcc tacaagcttt gtataagaat ctttaacttt tactcctcta ccagttatac
    24001 aacttacatc tccataacct ttaagagaac agcttttttc tatcccatta aactcgctat
    24061 caatatctac atcttgattt tcttgttgct gaattacttt ttgcattatt acatttactt
    24121 ccttaaaaat ttcattatct attttttcgc taatcttgct tccatactgg tctaccacta
    24181 ttactttatt ttttacattt tccatgctct ccgaaaaggt ggtatttata atattaaatc
    24241 cctcttcaaa cataacactt aatgtaacag ttcctttttc aataacatta aacttatcta
    24301 aattggcctc tatcatatac tttttctttg tctttttact tgcttctgta tatgcactca
    24361 ttattgtgtc ataaccattt actcctataa acatctttgt atacttgaca ttggtctttg
    24421 ctattattcc aactgaaagc ctattttcag caaatacttg ctttgctatg tcttcaacta
    24481 acttatcttt aaaattgtat gacacttcac tttgtgtaag taaaaatccc atatctttag
    24541 atacaaaact aatttcatta ctgcttgaat ctttagacct attaattatc attcctctaa
    24601 agagttcttt ctcatctaca tagaaacaga ctgtactagc tattggtata tcgatttgtt
    24661 ggaaatttac atcaaatgat gattgtatta ttgaaaactc tagtgtcctt gatggagatt
    24721 tataatcacc tgaccatgat accttgtcta ctatgtcagt tatgtcatat atacttccgt
    24781 tttttatgtg tacccaaatc ttaataataa aaaatcacct gccttttcat ttaattctat
    24841 cagcagttat ttataactta ttatctataa tagttattgt tttggagtta cttttggtat
    24901 ctttattctt ttatactctt ttaaatctaa tgtaaaatat acatctcgag tcccatctct
    24961 ttcttcataa ctaaaccctt caattatgac ttccatattt atatttgttt ccgtaattgt
    25021 aaatcttaat ataaaacctt ccttcatcca tttttctatc ttatttacac aatcatatgg
    25081 tgatggaaaa cctgtatagt cacagaaagt atagtcttta tttggaaaaa aacttgatat
    25141 tgaaatgctt ttaagagcta caccaccaaa agttgctatt tcacctattt tgagtatact
    25201 agaagagttt acagcagctt ttccattaat actaaaggaa gatggaaata ctggaaatct
    25261 aaatctatct tcagcttgtc taagccacat ttccattata agacaccccc taactgtgcc
    25321 aattggatac ttgcaactaa ttttgatgtt atcttttcta tatcagcttc ttctctaatc
    25381 actattgtat cagctaactt agctatgttt atatttccac cattttttct gcttctatat
    25441 tgatttgctt cttgtttagt taaaaccatt tcaccttcat ggagtctggt ttgatagtca
    25501 ttataaggaa catagttcaa tccaaatgca ttattacctt tcttacctga ataagcttta
    25561 ccagaatcac cagcctttgt tccagcatat ggattatctt tgtaattttt tttactcttt
    25621 tccactagat ttaaaactgt tcctgtgatg cttccatttt ttatcttatt aatcatagtt
    25681 tgccaccatt tacatatatc tttaactatt ttacatactt tatctaatat gttaaaaaaa
    25741 gctcccaata ttggctctat aattttccat ccagtttcca acagaggtcc taaggtctcc
    25801 catacagttt tccaaataac acccagtgtc tctataaaat tgtttatttg aggtgcatat
    25861 tcacctaaaa aagtaaaaat tcttgtgata ataggactaa cagcttcaac tacaggtccg
    25921 attagttgga atgctgtagt tactattgta ccaaatatac ttattaatcc ttgtgcaatt
    25981 ggtgatttat tgtttatact atctagtaaa ttatttacta agtttactac tggaagtaat
    26041 gaatctatta atgctgtaaa atcgatattt tgtaatagtg tacttcctgc gttaacaatt
    26101 gcttttggtg cattccctat cattgttgct gcatgatttt caaaacgttc ttgcttattt
    26161 tcaaccatca ttttacgctt ttcagcctca ttagaaattc gatattgagt agaatcagaa
    26221 aactcttttc cattttttac acttctagat tgcatctggt catatttgtt gccaataatt
    26281 atcttaccat tcattacatt gcctatttta ccagccattt tttcagataa gccagctaaa
    26341 ttgcctaatc cactttctat aaaagttttt attttcttta gtccttgacc taaaatatca
    26401 tcaaaaggtt taacaatact cttcaagcca ttgttaatgc ttgtttgagc tcctgatatt
    26461 atacctggta ttgtattact catttcttta gctaacccca tctgctttac acttatgcct
    26521 tccaatgctt catcaaaagt tttataattt tctcctacca gagtattaag agattccatg
    26581 tttccttttg ctgcacttaa gaaagctgct gatacatctt gttcactact tgtattcata
    26641 tttaaagctc taacatctac catagcttga gttatatctt tttctttttt gccaccagta
    26701 atattactaa tcattttagc tttagttccc attgcaacaa catcttcagg gtcaaaaggc
    26761 gtatcatttg ccattcttac taaactgcca taataatcat caacatctat ttgattaact
    26821 tttccagtat ttcttttcat tacactttct agaacaactt tctgattttg ttcctgacca
    26881 agtaaatcaa cacccttttt cacagcgaca cctatagtag caccatttgt caaatcagat
    26941 atcttccctt ttatcgaacc aagtattcca cttgccatat cctttacagc tattgcacca
    27001 ctccatacct tacctgcaaa taatctcaat ttgggaaata ctttacttat aatgccactt
    27061 gccatatctt ttatagctat tacaccactc caaaaagtat ttttaaacaa cattaactta
    27121 ggcaaaattc tacccatagc actactcacc atatctttaa gattaatact tccttgataa
    27181 ggacgtttct ctacttgttt taattttccc aagatactac ttatcactct cttagtcata
    27241 tcttttgctt ttattacgat attccaaatc ttgccaccaa tcttttttaa atttccaagt
    27301 aatttatttt tagttttttc tacttcatca cttttagctt taaatattaa tataatcata
    27361 atatttgaat taaactcatt tttcttttga atcaacttat taaaataatc aataatcata
    27421 gctatagtta ttgctagtct cataatactt ccatttaaac ttccaataac tcctgaaaca
    27481 gcatttatgc tagaacttaa ttttgtcata gttgaactta cactactagc agtagtttga
    27541 acttttctta acgaggaatt taaactgttt actctattac ttgcacttcc aatagaattt
    27601 tttatgctac tagccattac attagtggaa agtgaaacag ccacagttgc tctcctaaaa
    27661 ttatcagtta ctgatataat ttgattcatt tttggtgtgt aattatctgt aaggtacata
    27721 tttatacctt cttctctcac atttcccatt acataccacc tcctgtcaaa ggacacactc
    27781 catatccatg tttcattttt tcaacttctt cctcaatttc taaggcgaaa aaagcttcaa
    27841 taagctttaa ttcgccttta tccattgcat aaaaaaggga cggtcttata ccttttttct
    27901 tccaataata gtacattatt gtagtcctgg tatccgtccc tattagtttt ttacctcttc
    27961 tatcactgca tttttaccat aacccataac atcttgaagt attctatata agttggtaat
    28021 ttcacctggt aataataatt ttcttgctaa ttcttttggt gttggagcct taaatttatc
    28081 cattagctcc ttatttttaa ataaaagctt tccatccaaa tcacaaacac cttctataat
    28141 tgtaagcatc tgcatctccg gtaagtctat atccgttttc atattttcat caattttaag
    28201 acaagtattt tgtatttctt catctttact tattgttaaa gctctacaca ttactttaaa
    28261 ttcctgccca aatatagttg ataatctctt aagttcaact atagtacttg gtctttctaa
    28321 gttttctgta tctgaattta aaagtaaatc tactatgttt atattttttg ataatccatt
    28381 ttcactcatt attatttgct cctttatcaa tcaaattcaa tcaactaact tttttactta
    28441 ttaactatct gaatttatta agtatatact tactaaatat cagtataaaa ctaaatataa
    28501 aactaaatta tatcaagaaa atcatactca gtaaatgtga aaggagcttc tatctctcct
    28561 tttactccaa cctcccaatc agctaaagtt aaatcatcaa atgctatatt ttttactgct
    28621 attctttctg ctccataaga atctgggtca tttaattttg atatagcaac aaatctaggt
    28681 tcagaacctc tctttatctt ttctccaatt aacttgtgca ttcttgaact aacgtggtat
    28741 agagttattg agccttttcc tttatatccc atatactttg tatcagtacc catttgacct
    28801 gctattataa tatcttcttt tgtaaattcc atctttgctt gaaatttctt tacttctgct
    28861 actttgtttc catcaagcca aagttctccc caagtaccac tcattacatt tctagcttcc
    28921 atatttgcca tattaataat cctcctatat ttctattgat aaatctatat cttccatagc
    28981 atcaagtact tttatttttg cttttaaaaa tactttagaa cctgtgttag cttcttttat
    29041 ttcttgtaat gtcatataag ataaatctac tccttttgat tttaaatacg atttttgtgc
    29101 ttcaaaatct atttcaacag tagaatcaga ttctataagt gctgattttt ctaattcttc
    29161 taaataactt tttatagcta ctatcaataa acatttgttg tcataactgt tagtaacctt
    29221 tcctatatag tcatctatta tcacctttct tatgtcacta tgtataatat ctaaagtgtc
    29281 aactattttt attttctgga acatttctcc tttttctgct gttaattcag ttaaagaatt
    29341 tactcctcta gcaattctta tagctcctgc ttctttaata agtataagct ctcctttatt
    29401 aacccttgat tctgcatcaa ctttcgtcat cttaggtata tcgactacat cactaagttt
    29461 agtataagtt actgattgac ttaaaggtgt acctgctata agtccagcca ccctgcttgt
    29521 aaactcatca acactgtatt tcttttctcc aactaacaca tcttctgtag taaaattaat
    29581 tatcccttca tgatttccta caacttttcc taatacagct ttaaccttaa ccttatctat
    29641 atctctaagt ttaattatcc aattttttat agcagtctta tcagcttcta ctgcttttgg
    29701 catacataga taattaaatt ccttagtctc taaaaaatct aatgcagttt gaatatctgc
    29761 ttctccttct attacataaa ctaataattt atttggagtg ttaacatttc ccatcaaagc
    29821 taaatttata tattctttat tttcagcaga taaatcaact ggtatatcct ctttttcatg
    29881 tatttcatta agacctagtg ccttagcatc tttaagtacc attgcaatta ttcctctagc
    29941 tgaacgttct ttaacagttg tagctagctc cttaaatgat atgttgatac ttggtaatcc
    30001 tatagccata ctatcactct cctaaattta aattgatttc tttcatattt tcatatacta
    30061 catcttcttc atatacacta tccagatagt ttagtgtaaa tgtaaagttc aatacataaa
    30121 ttgactcttc ttttttaata ctttgttcta gctttgttat atttaatttt ctgtctgtta
    30181 cctttatatt tctgttaaat agcttattta attcatctga aatttcatac attctaatac
    30241 tctttgactg tggttttggt aagtatttta tagagataac aatatctttg ttattcgtat
    30301 ttaacattac aggtgtacaa ataactgata gtatacttac aaaaaaacaa gacccttcag
    30361 agccttgcac actttcatca tcaataaaaa tactttcagt aaagtttttt ttgagaatct
    30421 caataattgt ttctaatatt tccttgtatt taagcaaata atcaccacac tatcactaaa
    30481 tattcttgct taatctgata atcttactat aaatgatata agtcattttt aaatatatat
    30541 ctcatttatt cctgtcaagt atcttctata tttttaggta atattattct tttcaatcta
    30601 tcacctcctt caatatggat ttctttcaca ataacattat ctcacatatt ttattgccta
    30661 ttgttgcaat ggtgtatata aagtgttgta aaattgtcct attttttata atatctcact
    30721 caatttaaat atcatctttt tctttaaatt gtagcaagat gttctatcta agtgtagttt
    30781 catagaaata tatgtcatat tgttttttgt cttactatta taaaaaagat taaaaaattc
    30841 catttctata tcatttagac acgttagagc attttctatc ttctcttttt ctatttctat
    30901 atcttctttt tccattttta attttcttaa tctttcctct ctttttaaca cctcattttc
    30961 cacagaagag cttatgttat atgtgttact agtcttttct gtatatacca ttgctccaca
    31021 tccagagtat tcattctcac atctttttat gtccaagtta atattcttta tctttatatc
    31081 caaatactta taattatgta atcttttatc tgtttcttta aataatatat cttttttgtt
    31141 ttccatagta cttccccttt tttatatact tattattagc ttcaaattta caataatctc
    31201 tttagtgcac agttttttac taatctcaca actttcaaga acatattgtt ctataactgt
    31261 ataaaaaaaa cttcttctat attttgttct aaaatactag aaatcttctt agccataaga
    31321 agtccaggat tttttatacc tctttctatt tgagatatat aatcatttgt aattccagcc
    31381 tttctggcaa gttgaatttg tgtcatacct ttgcattttc tataatattt caagttattt
    31441 ttaaacattg ttttatacct ccattactat taagaatatt ttgttcttcc tcacttagat
    31501 tatatagaat tatttgttct ttatcaatag attttagaaa aaaatattct tttatatttt
    31561 attagtttta ttttttagaa caatttgtta taatctatac ataaggtggt gttataatgt
    31621 ttgccaaaag attaagagaa cttagaaagg aatttggatt gactcaaaga gaacttggag
    31681 aaaaagtagg cgtttcccaa agagtcttag ggtactatga aacagaaaac agatttcctg
    31741 atgaacacat tttaaataaa ttggctgatg tatttaatgt atcagttgat taccttcttg
    31801 gaagaacctt agttaaggaa aatattgata cagtagctgc acatagaaaa aatccacatg
    31861 aagagttacc tgaagaagca caagaacaac ttaatgatta tatagaattt ttactaaata
    31921 aatataaaaa aaaataaacc atatgatgag cagtctattt ttctgctctt ttaatataat
    31981 ttaaaggcaa acatacattc tattttaggg ggatttttat gaataatttg gataagcttt
    32041 ttgaattagc ttctcaagaa gagataataa ttcattatac cacttatatt gcaggtgatt
    32101 tagaaggact atatataaac aaacatggta ttaaaattat atcattactc agtaatttaa
    32161 aacaaaactc aaaaaaattg acatccatct tagctgaaga acttggacat catttcacta
    32221 gccttggata ctatgtatcc tcttataacg attattatac aaaaattatt atagataagt
    32281 gcgaaaataa agccttaaaa tgggcttgtg agttcttaat tactgaagaa gatataataa
    32341 acataattaa ctctggcatc acttgcgttt atgaaatggc agacatactt aatgtggata
    32401 ttactttctt tcaaaaaaga ttagaatttc tatcattaaa aaaacagtct ttacaacttg
    32461 gaaataataa atatttaata ttaactaatt tgccgtattt ctacatattt gatccaattt
    32521 cataataaaa atagtagtaa ttttaactgg cttaacagta aaatctatat atttatttta
    32581 acaaattttg gtttctataa attcaatatt aatatataat aatgatatca tattatttaa
    32641 aattctaaaa acaaatatat gcttttgtta agaaaggttg tttgatgaat gtataaagaa
    32701 aagttgtttg ataattattt taagttctta gcactattat tttggccaat tatgtggtat
    32761 aagtggatag taatttcaaa tggtactctt gaaaatatgt tatttaccat atatgcaatc
    32821 gtcgcaattg ttttcatcat tttatattcg gtgtttatga taaaatataa agacattaca
    32881 caaatagatt tcttttacag gataagtact ctacttgctt ttatatttac actttttagc
    32941 tttttaatat acccaaagag tttatttttc ttgtatttaa agattatttt tactggaata
    33001 tacctttatt attcaatagt aaaaactctt aaatttaaag atgacgaagg tgtagtgggt
    33061 attatgagct cacttttatt aattgtaata actttgttct actaaattta attctatttg
    33121 acttaatatg gctttaaata ttagacatct acattatttt ctgatattat ttaagatggt
    33181 agtcttatat taataatgaa atacactatg aaggagttaa ctattatgga aaaaaaagtt
    33241 ttagcaacag ttggagaaaa agagataact aatattgata ttgaaaatgc attaaaatca
    33301 ttagaccctt atcaagctat gcaatttaaa actgaagaag gaaaaaaaca cttattaaat
    33361 gatttagtga atcaagaatt attcttctta gatgctaaag aagaaaaatt agatgaagaa
    33421 gaaatattta aattagaaat gaaaaagata gaagaaaatg tattaaagca atttgctata
    33481 aataaagttt tatctagtgt taatgtaaca gaagatgaaa aagtaaaatt ctttgaagct
    33541 aataagagct ctttctctaa accagaaagt gcaactgcta aacatatatt agtagatagt
    33601 gatgaaaaag ctaaagaaat acttgctcaa ataaaatcag aagaaatatc ttttgaagat
    33661 gcagctctta aacattcttc ttgcccatct aaagatatgg gtggtgattt aggaacattc
    33721 ggtagaggac aaatggttcc tgaatttgaa gaagctgtgt tctctatggc taaaggtgaa
    33781 gtaagtgaac cagttaaaac tcaatttgga taccatataa taaaattaga agaccttcaa
    33841 gaaagtacag agtctacatt tgatgaagtt aaggctgaag ttgaaaaaag tttattatat
    33901 caaaaacaaa atgaagttta tggaaataag ataaatgctc ttaatgctaa gtacggaaac
    33961 cttgtaaaat acaacgatta atcataaggt catatataaa aaagctgtct tttcacaata
    34021 tttattagaa aagacagctt tttatattaa agtttaaata ttcagtttca tattatcatt
    34081 cttttattgt aaagaactca gcttaaaagt ttaaataaga tttttaatta tcattagcta
    34141 aatttttata tccacgtatt atctcataac agtaacctat tacatctctt ctttttatta
    34201 tcccaataaa tgtgtcttgg tcatctataa caggaatgaa attttgattt aaagatttta
    34261 taactaaatc ttcaatatct gcgttgatgg aaacaggaga attatccatt tttctattta
    34321 tatctgtcac tggaacatct tccaatccct ttaagtccag atttaaatca ttttttaatg
    34381 tccataaaaa atcaccttct gttatagttc caacatattt accatcctta cttattattg
    34441 gaattgcaga gtatttgtga tattccattt tttctagggc ttgccttata gtgtagtctt
    34501 catatatata tgctacttca ctttttggtg ttagaaagaa taatatgttc attacactac
    34561 ccaccgttac tgaaaactta taaatattac tcaatattta taatgttact tttttgcagt
    34621 aactttctcc tttcttattt tctaagtatt cttaatacta tacgctgtaa caagcgtttt
    34681 tcctttgctc attttaatct tattatgctt tattaatatt tttatatggt ctatcagtat
    34741 cacttattct ctttttagaa aatttactaa aaattaattg acttaaactt agccataata
    34801 attttactct acactattaa ttttaacata tttatctcat tattaatgat tttattttaa
    34861 taattttaat ttattttgct attaatttta tttacaaaaa ctgaaaaaac cgctaaatga
    34921 ttagcggctt atctctcata ttactagaac actaatatat atgaattttt aattataatc
    34981 taactacgtt agcagcttga ggacctttag ctccatctac tacttcgaac tcaacgcttt
    35041 gtccttcttc taatgttttg tatccatctc cagttatagc tgagaaatgt acgaaaacat
    35101 ctccttcacc ttctacagat atgaatccaa atcctttttc gttgttaaac catttaacta
    35161 caccagtttt cattaataaa tcctcctaaa aaaacacaaa tatttagcta ctcttttctg
    35221 taaccttatt actactctat catatatagc tatgtttgtc aattattatt atttttatac
    35281 attaataatc aattttttta ctttataatt ttaaatgatt attatctttt acactttatt
    35341 tttctttata attttttaat aatttatttt tattatatgg aatcttatgg acttatcact
    35401 ccaacctaaa tcccatggca ccaacattct atcagtatta tgacaagtta ccaaaggata
    35461 ccctcttgag tctaatcctg tcactgtcga aacatgtgtt attctgcctt tcttctcata
    35521 accaacaaaa tcccctggac gtaaattata agcttctttg tatacttctt cataggaacc
    35581 tttagcaatt aatgaacctc ttccactata cagtgcataa tttttaaaag cttgtgcatt
    35641 tacccatgct tttgtacctg ctctctcgct ataattccaa attgagttct ttttgaacct
    35701 tccactttca aacattatct gtgatgcaaa gtttgcacaa tctccacctt ctggattata
    35761 atccctatag tttggattaa atttcatacc atgttcttca tcagctgcgg ctccacagta
    35821 tttatgtgca taatctatag cctttttttg ttcatctgta agctgtaact ctacaccatc
    35881 ttgttgacca atataatttc ttatatcatc agattttata ttttctaaat ttaaagagtc
    35941 tgcaaaaggg tctgtatacc actctttagt tatgacatat tgattatcta taatttttac
    36001 atttagataa tgatatgtac ctattctaaa ggcattttct ttgtcctttt gattttcata
    36061 tgaatactta tattcagtcg atactgaaca gattatacca tagaggtctt tttctttttc
    36121 ttttattttt ttaatcttaa cccttgtctt tatgtcttta aattttacac cttgcttact
    36181 agaccaattt tctaaatact tcatcttttt tacttcattt tcataagccc acagaccaaa
    36241 ttttttatcc gtctcataaa gaccttttaa aatgttttca tttttctcta atattgcctt
    36301 atttctgtaa tcaaataagt tttcaagcaa tagtttatat tggtctttta catcatcacc
    36361 ttcaacattt gcagattcca tgactttttc ttccatattt ttcatactta aatcattgat
    36421 taaaaataca cctgctgtag tagctaaaga caaaaataca aatgccatta tacctttgat
    36481 gtacttattc ttatttttca gtattttcaa agctacacct cccaaatagt acaccttaca
    36541 aatcaaatta caaagaatat tctgtcacat atagtaattt tcatatttaa taattctcta
    36601 ttttattatg tccaatatta aaaattaatt gtatcaatac actgtttttt ttacaatttt
    36661 ttattttata atctactttt ttcttttttt tatagtaata tatatgtata taaatatttt
    36721 ggtatcatta taattaatac atactaatgg agggtttttt atgcaaaaaa aagtcgcagc
    36781 aattaatgac ttatctggaa taggaaaatg ctcattatcg gttgctatac ctatactttc
    36841 agcattaaag gttcaatgtt gtccatttcc aacggccata ctttcaagtc aaactggtta
    36901 tcctgaattt acttttttag actttaccga tgaaatggta aaatattcaa atgtttggaa
    36961 aaatttaaaa gtcaattttg atagtatata tagtggtttt ttgggttcaa agcatcaaat
    37021 tgagatagtg gctaatttta taaacgatta tcccaatgct tttatcgtag ttgaccctgt
    37081 gatgggtgat aatggagtta tgtatccaat attcacagaa gaaatgagac atgaaattaa
    37141 agaattagtt aaacattcag atttaactac tcctaattta acagaagctt gtttcttaac
    37201 tggaaatgat tataccaaaa gcgattataa tagagatgag cttatatata ttgcaaaatc
    37261 tgtatctgat ttgggaccta gcaaagtcgt tattactggt atattagaag atgataatat
    37321 attaaatttg gcttacgata gagataatga ccatgtattc tttacatcag tcaaatataa
    37381 taattgttct tatagtggaa ctggagatat attcacatct atactttgtg gtatgttagt
    37441 aaataaacat gatttgggag tagcggttaa tactgcaaca gattttatat ataaaactat
    37501 aaattacaca tctcaatttg atactgatag aaatgatgga gttatgtttg aaaacttttt
    37561 atcagattta actaatatat aaagtcaaaa aaactatcca ttttataaat acctataaat
    37621 cataaaattt aggtatttac aaaatggata ttatttacta aactattggt atttcaattg
    37681 ttaccatagc accaccagtt ttcacagaat tttcaatata taaaatccca ttatgttttt
    37741 gtacaatatt atttacaata tagagtccca ttccataatg agatttagaa tttctactca
    37801 aatctcctgt ataaaactgt tctgtagctt ttgacaaatc tgctttagaa aaaccacttc
    37861 cacaatctgt aactacaaat tttaagtatt tattacgtac tgatacactt atgtatagtt
    37921 tactctggct tggtgaataa tctatagcat ttgaaattat attcataata gctctgaata
    37981 acagttctct atctatagtt atatttttag gcaaattatc ttgtttataa aactccacat
    38041 ctaagttttt agtactagct aatgcttcta tttgcactaa gacatctttt ataaactcac
    38101 tcatactgat tgcttcttta tttaatatat agccattctc tgtttttgat atatctatta
    38161 aagtattaat atatttttct atttgagtga caccctttga gatatattcc atgtattcta
    38221 ataactcagg attttcattt atttcaatta ataagtcagt atttccatgt ataattgtta
    38281 gtggtgtttt tatatcatgt gccagtgcag atatctgttc ctttctattt tcttctagca
    38341 tccattgttt ttctaaagaa tcttttaacg ccaacttcat tttatccata gaaaaaagga
    38401 cattattaat ttcataaatt ttactagatt ctacaacaaa atctaaatcc tgttgttcta
    38461 ttttttctgt agtatttttt aaaagctcca tttcaatatt aaatttcttg ccaaatactt
    38521 ttgataatat aacaatttca ataaaaaata ttatactaaa aataatcata cccaatgtct
    38581 ctggttttgg taaatatgct cttaaaattg gagaactata ctctgatact attttgtatt
    38641 ttattataaa aacttcatct ttcttaaaaa actttatata actttctgaa tatgcatgcc
    38701 tttcttcaat atctctcatt aaattccata cttcttttga ttctttttta ttaaaggtcc
    38761 ctgaaattaa actcccatcc aaagtataaa ccccatactc atatatactt ggaattatat
    38821 cttcagttac tttttcactt gaaataatct gttctttata tttattaaat tgtttttctg
    38881 cataattagc tggtaaaatt acacctgatg ataataatac agaaaatgat aacattaaaa
    38941 ggagtacaat tgaaattgtc ataataaaga ataaagataa atattttata aaaatagttc
    39001 ttaacttttc aacttttttg ttgttagatt ttttacctcc aagcatttgt accctgtcct
    39061 ccaatagttt aattaattca taattaatat ctaaccagtt ttttatttga ttattttata
    39121 tctttttatt gctaagttat attttaacat aataatataa ataaacagtc aatttttact
    39181 ctattcttct gattttttac cttcccattt agaaaaccaa atacataaaa ttacaaatgc
    39241 taaaattgtt acaaaaccac acattaaacc tgttgattga tatgctttta ttgattcaac
    39301 ctttatatat tcaaccgttt tagaactcga aaaagacgac caaatagtta taaatctaac
    39361 accccatgca caaggaaaat actgccaaat accagaaccc aatccagtta ataataatgc
    39421 tgaaagtaac atttcaacta tacctactcc aattgatgtt ccttttccga accttaaact
    39481 taagaataaa tgtaatatgt attcaaataa attacaccca attaaaatta gaattgaaat
    39541 catataaaag cttgatgcaa agtaagcctt agatatacca aatttaaaac ctaatacaga
    39601 cactaatgtt gctacaaaac caagacatac taagattata tatttactta taagagtaag
    39661 atattttgga ttagatgttg ttaacatatg tttataattc cctgcataat attcttgttc
    39721 aacaaacatt gaacacacaa cacctgacaa taaaggaaaa gctattgcta taacttgtaa
    39781 atatgctact atctttagta tattatcagc tcctgaaacc ttataatacc ataaaaacaa
    39841 tcccatcccc attaaagcaa tgcaaatgtg cattagtatt ataaaatttc tctttaattt
    39901 tattaaatca gaacaaaata ttcttattaa ctgtctcata ttacttcacc tctctattat
    39961 tgaaccaaac ccttgtagct aaagcaaata atacaaataa aacaatagat attaatactc
    40021 ctggcaaaat aacagcatta tttaaaaatt cacttccctc tggtacagga agaccatttg
    40081 gcagaatatg caatacaaca gccattaatc ttgaaggaat cgaatatgga aacatatacc
    40141 acatttctgt agttgagaaa acagcaactc caacaatagt aaagaacata tttattagaa
    40201 ctgtaacaaa tataccaaat tttgaagcta aaaacataca aagaggaatc tgccacataa
    40261 atagtaaaat aattaatata gttgcaatga tattttgacc tattgaaata gtttctttat
    40321 agattatccc aacaaaaact acacctattg cagaaataat tgatgctata aaacaacaaa
    40381 taatacagta aatcattttt ccagtccaaa cgtctttcat ttcaattggc aatggtaaaa
    40441 taccacgata tttacttttt tcatctttta atactattaa agaagatatt aatgttaatg
    40501 ctcctggaag aaatgtcgta taccaccagt tgaaagcagc attttgccct ccacctagtc
    40561 cacataaaag tatacaaaac actggaacta tccatatcaa cttcattcca aaagttcctt
    40621 tcatcttttg aaattccact ctaataaatc tttccatatt actgccctct ctttctattt
    40681 tcagctacaa ctttcataaa aagtttttct aagttttgtt cttttgatac ttctccttga
    40741 taacccatta ctccattaga aattattcct atttcatcta caacttgttc aacttcagac
    40801 aagatatggc ttgataaaat aactgtaatt ccttgttttg gaaaagaacg aatcaattct
    40861 ctaagttctt caataccaat agggtcaaga ccatttgtag gctcatctaa gattaaaagt
    40921 tttgggtgat ttaataatgc aatagcaata ccaaggcgtt gcttcatgcc tagagagaat
    40981 tgacctgaac gctttttaaa ggtatctctt aaatctacag tctctaaaac ttcttcaatg
    41041 cgagagtcag gaagaccaag taaagtagta tggactttta aattttctcg tgctgttaaa
    41101 ttctcatata tagcaggaga ctcaataaga gaaccaatat ttgataaatc ctttctagtc
    41161 catctatgtc cctcaaacat tatttttcct gaagttggat ttaaaatccc agttatcatt
    41221 tttaataaag tagatttccc agctccattt ggtcctaata atccatatat agaattagat
    41281 ttaattgcta gtgaaatgtt atcaactgcc atctgctcct taaatttttt agaaactcct
    41341 tttacctgca aaatataatt actcataatt ttcatccttt cttttgtcaa acttatttac
    41401 aagaatcatt ctaaatcata aatataagga ttttataaga attaaaaaac aaaaaaagat
    41461 gtgttaaaaa cacatctttt tttatcttaa ttctattaat tttccattgt agtatatctc
    41521 tacttcttca atccaaatgc tattatcttc ttcttggatg acatttttaa taatattatt
    41581 tatagtatat attatatttt gttcattcaa ataatcatct ttccaagaaa ctctactttt
    41641 tttatctggt tctatcaagt ttattttaac aagattatct ttttccttaa cttctacttc
    41701 catgtctaaa ccattaaaat actcatttga taatgtatct aagattaatc gcagtttatc
    41761 cttaagtgaa ctttcttcat caatctgtaa gtactttact attttctcat cctttgaaat
    41821 tatctctata ggtattttag tagttttttt agaattaatc attttactag ttgtttcttc
    41881 ttttgcatct tcatccttct ttacaactgc tgattcttta gaatcaacta gctcaactgc
    41941 actgatgcta taatccatac atgccgtact caataaagta gtagcaatta ttaaaaaact
    42001 tactgctatt ttattcataa gtatccctct cctaattctc tttcgatact tattatacca
    42061 tagtatagat tatattttta tacttttaaa tcaatttata aattattata gtaaattatt
    42121 tacaattcta agctatttga atttattttt atagtatatt ctttctctaa attcgacaga
    42181 tttttattca aaagcccttt tatttctctc gtatttctat acttgttgct atgttcttca
    42241 ctatgttcat aatcatatga atcattgtca tattcttcat cattattaaa ttcttcaatt
    42301 gcttcttttg actttatatc acaattaaat ttatacttat ttactggtat atcaagtctt
    42361 accttagaat ttggaacttc tatgtccagg aacttagcaa ttggcatatc agagtacaag
    42421 taaaattcac tttcataatt tgaatttcta cctattttct cttttatatt tacattttca
    42481 ggtatatact cttctatatt attgataaat acatcttcat tctctgaaga tatatacaat
    42541 gactctgatt ctatgtttac atttttaacg cctaaaattg attttgttga caagtgaaga
    42601 ttgttattag atattaagtt taggttttct aatctattta ctttgttctc tgttatagct
    42661 ctactaaaac ctccataaga agttttatat gttatagtat ttgaagctac attatcgtat
    42721 acaaataagt gtgagcttat acttgatgca tttatgtcta cattatttgg tacatatatt
    42781 ataatttctc tataatcatg tgaaaacata ctatttatag atgtatttaa taattggtcg
    42841 aaatttttaa tctttttaat tttattttca tattttcttt caccttttac aactaaagtc
    42901 ttatctttta aagttacatt gtatttgtaa aactcattat ttcctcttgt tgttacacgc
    42961 acatcttcac ttgaactttt ctttattgta acgtttatat tgtcaacagc tatatctaac
    43021 ttgtcaatat ttactttttc ttgataaagt ttattttctt ttttaaattc agcttccttt
    43081 tctaaaccaa agtttattag gcttggcata actaaaatcc ctgaccatgt tgtccctatt
    43141 atacctatta ccaataaaac cgcagcaaat atagcaagtt ttttattcat gtttatcttc
    43201 tcctttctta ttttctatat cttcaaggtc cttatatatc gcctcaaaat ttatactatc
    43261 atcattatat tcatcagttt cttttatgct ttcttcttct ctattgtagt aatcattatt
    43321 atatgaatct tcattaatgt ctttattcaa atcttcatca tttaaagtag ctttttttct
    43381 tttttccatc ttttcatttg cttttatata aatatttttt ctctttatcc aatgtatata
    43441 attatttagt aattgtttac ctagttttat ggcaaataat aaaatttgcc atgcaagtat
    43501 ctcaagccct acaaatgcta tggttgcgaa aatacaaaac atcataacat ctggaaccat
    43561 tgctataaat ttaatcacaa atggaattaa tataacaaaa gcaattaatg agcatactaa
    43621 tgcaatagta gcagatacaa tagcacatac aaacgcaaat gctggaacaa ttagaaataa
    43681 agataacact actaataacc cctttataac ttgtctggat aatcctccta caccttcttc
    43741 tatacttggt gtaagtttat catttatatt ttcttttgat ttattgtact tttccttagc
    43801 ttcatctttc aagatagaat aatccttttt tacatttgat ttaaatctac taaatttacc
    43861 atttaatatg tctgtattca ttatttttcc atctatattt tcttttgatt tactatactt
    43921 ttcttttgct tcatctttta agatagagta accttttttc atatctgatt taaatttact
    43981 aaacttatca ttcaaaacat ctgtatttat tattttttcc tcttcaatat ttttttcttt
    44041 agtttgtaag ataagttctt ttgctataga ttttggtgag ccaagtgatg ctattatctc
    44101 catatcactc tttccctcta taagaccatc tacaaaatac tcttcataat ctctcaatat
    44161 atcattaact tcgctctcag aaaaatcttt ttttagataa tcctttaaaa tttcaagaaa
    44221 ctcagtttta ttcaagttca ttacctccct catcttcact tattaaaatc tcaacagcct
    44281 ttacaaattc tctccactct tccatcagat tggataaatt ctcttttcct agtgaagtta
    44341 ttctatagta ttttctagca ggaccttcat tagattctag tatatatgtt tcgaaataca
    44401 aatcttttgt aagtcttctt agaataggat atattgttcc ttcatttaca tctattactt
    44461 tagagatgtt atgtactatc tcatatccat acatatcttt cttagatatg agagcaagta
    44521 cacaaatttc taaaacaccc tttctaaatt gtgtgttcat atactccatc ctttctttaa
    44581 atacacagta ttgtgtttta caaggtacta tgttaaaact tcttatatcc tcataataac
    44641 acagtactat gttctgcaca atagttattt ttaaatattc ttgttgatta aatccttcta
    44701 taaatgtata atactctaat cagatatatt ttatgaaagt ggtgataaat tggctaaaat
    44761 gaaagatgat aaaacaatat taatcctaac tgctcaattt ggtgctggac atataagtgc
    44821 tgcaaaagca gtcaaagaat gtattattga aaaatatagt aactataatg ttgttataca
    44881 aaactttata aatgcaagta ttcccatgat gaataagcct atggtaaaac tttatgaaaa
    44941 caatacaaaa tatactcctg gattatataa ttactattat tactttaaga aatcgtttga
    45001 ttcaagacat gatttatctc ataaattata tacacctaaa ctttctgagt atattgctga
    45061 tataaatcca gatttgatta tctctacatt tccactagct gctgcttgtg taaataactt
    45121 taagataaaa aatcctgata taaatatacc tacacttaca gttataacag atgttgtaga
    45181 tagtatggaa tgggtttttg aaaatacaga tttgtatttt gttccttctc ctgaaataaa
    45241 aaatagattt tttcagaaag gaataaatcc tgactccata aaggttactg gagttcctgt
    45301 tgataagaga tttcaaattg aaagtaaaga actatgttgt gataaatata gactattact
    45361 tctaggtgga ggaagaggtc tatttgatat agatgaggat tttatgcatt ggatagatga
    45421 atttattgaa gaacatagta attctataga aattacaata gttactggta aaaacaaaaa
    45481 attatatgac aatctaactc ataaaaaacc tctaaaaaat attaaagtac ttggatttgt
    45541 aaacgacatg tataatctaa taagagaatg tgacctaatg ctaactaagc ctggaggagc
    45601 aactatattt gaagctattc aatcacaaac tccagtactc gtaaaaatgc caaaagttgg
    45661 acaagaaatt gaaaacgcta aatttataat agataagggt cttggcatga tttatagtga
    45721 tgacctagac cttaaaaaca tattttataa attagtatca aatgaatttg attctataat
    45781 aaactttatg aaaaaaaatt taaaagaatt taaaacagtc attcatccag agaaaattgc
    45841 tgattatata tcagaattaa tagataatca ttacagttaa attgtactat taaaaaattt
    45901 caaacataaa attaaaggca atcaagtatg attttacact tgagaattta ctcatagtgt
    45961 ttaataatac ttgattgcct ttatcatatc aaaatcaaat tgttatatta gtatatattt
    46021 ttcttgtact gcatatacag ttgttgtatt tcttccatac ttctctttaa ttctatttgt
    46081 aaatctgaag cagtctggta atccttattt tctatagctt ctctcactct agtgaatagt
    46141 gattctctag ttaaagtatc cttcataata ttgaacttta aatccgatat tgagttccaa
    46201 actacctcat caagcgcatc catattttct tttgtgtgta tcttgacaat acttcttatt
    46261 ttttgaatcc cagcctctat tattctagtt tttaatttct tttgccactt atctatagct
    46321 ccaatcttaa atgattctat tatactatca gtaaatacat caccttgttt taaagatttt
    46381 aattttgaag catatatttc taagtttttc atattttcat aaactgtagc tggtggtatt
    46441 ccaaatcttg catttctttc ttccaaacta taatgttcaa atacatcatt ttcatctcta
    46501 tatgctctat ctttttctaa atagaaactt tcttcaccta catttttaga taactctttt
    46561 tcaagttctt ttgtactaag accactctta gctgctgctt ttataccatc caacattgtt
    46621 tgataacatc ctgctattac taaatacgtg ttagatagag ggcttggtga ccttaattca
    46681 aatcttacag tctttggatt tttcatatct cttattaatc caacaagcac tgacctattt
    46741 cttgatggaa tctcataact atgccctaaa gatgtaacta tacatacagg agcttcaaat
    46801 ccaggaacta atctattaaa tccatcatta gaagctgtta caattgggtt taatacttca
    46861 taattgtaaa gaagtcccat aagagcccca tatcctagtt cacttagata atcttctttt
    46921 aaatcttttg gagcaaatag attttttata cttccatcct ttaacttcgc acttactcct
    46981 acatgtgtat gtccaccact tcctgctact ccatgaattg gttttgcttt aaatgtaact
    47041 tctagtccat gtgatgtaaa tacatcctct ataacatctc ttactaataa ttcattgtct
    47101 gctgcttgta atggtgtaga aaacttccaa gaaacctcta attgctccat agcatggttt
    47161 gttcttccat ctatactaat agaactttgt attcctccga cctctttgtg agccatttca
    47221 gggtttacac ctagcttttg aagtataatt aaacttttct ctaaacaagt tcttataata
    47281 ccatgagttc ttttccagta ttgctctttt aggctttgtg atacatataa tttctctaag
    47341 tcagctttat cctcaggagt attaacccag aactcaagtt ctgtagctgc tgttaacatt
    47401 atttcctcta tatcatctac tgaatctatt cctatgttat ttattacatg tggatattct
    47461 ctaaatattt catacattga ctttttaaag tacttatctg ctttttgaag tactcctcta
    47521 gaacatactt ttttattatc atgtattaaa aatgcaggta tctttaatgt tccaacaggt
    47581 agacctactt cttcgtctat atattccata ttgtaatcta cataccaatg acaactttta
    47641 tctggcatta aatctacttt cgcattattt aatgtagcta tattataaag ctcaacactt
    47701 gaaccatcag tctgtatagc tgattccaaa aatttatcta tatcctccaa aaataattct
    47761 acaggaatct tttcatctgt tgcatttcct cctaaatcaa cccccattaa ggaaacaaat
    47821 cttatatttt tattgctttt taggatttct cttaattctt cattagtgtg tttatctttc
    47881 tctattacgt ataatagact atccattttt ccactctccc ataattttta tgtatatttt
    47941 attttgttaa atacaagata aatttcattt tccttacatt tatgaatttt tcttgcaaat
    48001 tattcgtgtt ttattcgtgt ttttatttat attattatat atcaagtata aaaagttcgc
    48061 aatatttttt attggaaaaa atattataca tacaatagtt taacattttt acaaatatgg
    48121 ggtatactaa aataaaagta tttttatttg aaaatttaat tttatttata atataatcta
    48181 tagtaaaaga aataataaaa aaatttagga gataaacttt atggaataca taattttcga
    48241 tttggaattt aaccaaggat ttgataaaaa actcaataaa actgtatcca atgaaaagtg
    48301 tccttttgaa attatacaaa taggagcaat taaattggat tctaaattca atataataga
    48361 tacgtttaat agttatgtaa aacctacaat ttataaagac atacatccct ttattagtcg
    48421 tatgactaat attaaaaatt ctgattttaa tgattcgcct actttccctg aggtctacaa
    48481 caattttata aaatttatat catcacaaga ccctatatta tgtgtttggg gagctggaga
    48541 tttaaaggaa ttatacagga atatcaacta tcacaagcta ccatcaaatt ccttacctaa
    48601 atcttatatt aatatacaac aacatgcatc taaatatttc aataatccag caggaaaaag
    48661 cattggccta caaaatgcta tttctatatt agaacttgat gaaaaaatgt cttatcacaa
    48721 tgctttaaat gatgcatatt atactgctaa agtttttatt aagatataca atccaagtat
    48781 agtcccagat atatatcttt atacaagtat aaaacctaaa actataagat attctaacaa
    48841 aaaaagagtt gattatgata agttatttga tgaatttagg aaaattttaa atcgtgaatt
    48901 aactaaagac gagaaaaaaa tcattaactt agcttataat atggggaaaa caaatcaatt
    48961 tacattagaa aatgttaagc aaagaaaaaa caaatagagt ttatttagat aaaaaatagg
    49021 catgtagatt aaaaaactag ttaactttaa atttatatct acagcccaat ttttatcata
    49081 attaattttt attttatctc taattcaact ggacaatggt ctgaacctaa tatttcagtg
    49141 tgtatatccg cacttactaa tctatcttct aattttttgg atgcacaaaa ataatctatt
    49201 ctccaccctg cattattttt tcttgcatta aatctatatg accaccaact ataaacacct
    49261 tctttatcag gattaaaata tctatatgtg tctataaacc cactgtctaa taatttagaa
    49321 aacttctctc tttcttcttt agtaaaacct gcatttttca tattattttt aggatttttt
    49381 aaatctattt ctttatgtgc aacgttcata tctccacaca caattacagg cttatgatta
    49441 tctagtttgg ttaaataatc tataaagtcg tcttcccatc tagttctata ttctagtctc
    49501 tttaattcag attgagaatt tggcgtatat actgtaacaa agtaaaaatc ttcaaactct
    49561 agagttatca ctctaccctc tttgtcatgt tcttctatat ttattccata cattactttt
    49621 aaaggctctt tttttgtaaa tatagcagta cctgaataac cctttctctc agcataattc
    49681 caatattgaa aatatcctgg taaatctaac tctatttgcc cttcttgcaa tttagtttct
    49741 tgtaaacaaa atatatctgc atctacttct ttgaaaaagt ctaaaaatcc tttcccaaca
    49801 caagctctta ttccattaac attccatgat ataaatttca tacttatact cctcatctaa
    49861 acattgacac actccccata gctaaagatg ggggcttttc aacaatttta ttgtaaattc
    49921 ttaattcact tttattttaa caatgctata ctataatttc atctaaaatt actatttact
    49981 taatacctaa aaatatatgt tttaatcaat ttttaacttt tttgttaaat cttcagggct
    50041 cattgaagaa acatacatat ttgttccaag ttcaaatcct ccaaaattat attttcttgg
    50101 gattatgtgc atatgaacat taaaatacga ttttgtttca atctttgttg gatgagtgtg
    50161 aatacataaa ttaaatggca tatatccatt gatattatat aacttcttaa acaacttttc
    50221 aaatattgta gaaagctcct gtatattatt atcatttaac tcaccaaact ctattttatc
    50281 tttaaatatt attcttactt ctccactata cttggttgca tatggtataa gtaccaaaaa
    50341 agcttctcca ttataaacaa ctcttctatc taaacttatt tcattttcta ttaaatcatc
    50401 atacaaagag cttttattgc tgtcataata ctcctttgaa accaacagtt cattcgtaat
    50461 ttcaggtgga ataaaagaca tagacaatat ttgagcatgt ggatgcatca aagatgctcc
    50521 tgcctttctc aagaagtttt tgaagatact aacatactct actttatcat ctttcgacaa
    50581 atctctaaat ctatttctat acataaaaaa aacatcttca aattcttttt gactcatgtt
    50641 ataaaaacta cgattatgtt tatcgctctc tatcattact tcatgaacac catatacatc
    50701 tcttgccata tcatcaatta taggaaattt attgtagaca gattttacaa gccatccttc
    50761 ttcactttct atttcaaata atgcatcagt tgcatgagct tcatttcctt tgcaaaatgg
    50821 gcattcttca tcatattcat tagtttcttc atcttcattt gggatatctg ctgtatctaa
    50881 aggtcttttt aacctatctg tagcaaatat aacaacatca ttggtaattg gatctattct
    50941 taattctttc ataattaaca cctcttagtt aatagccttt aatataatta tatgatattt
    51001 atcgtatctg ttaaataaat ttataatatt ttttataatt ttgcatattt attattatat
    51061 attttgtcta tagctgaaag attataacta aaaaatcact atcagtatat cagaatatta
    51121 tcttactata aattaattta tgaatacata atttagtggc ataaacatgg gtattttact
    51181 ataatttgtt aaaagtttat tttaaagcta tattaatttt ttttgatgat ttttacccat
    51241 aagtatgtta ttattatctt gtaaagatgt cttgtattca aacatacaat ttacataata
    51301 caatatacgt atttaaatta aatagggggt attaaaatga attattcaaa cagagttagt
    51361 gcaatgcaag cctctccaat cagaaaactt gttccatttg cacaagcagc aaaagataaa
    51421 ggaatcaaag tatatcactt aaacatagga caaccagaca taaaaactcc taaaggattt
    51481 tttgatgctg ttaaaaactt tgatagcgaa gtcttagaat atgctacatc agaaggtatt
    51541 ccagaattat tagaagcact tcaaaattac tataaaactt acgatatgaa ttttgaaaaa
    51601 gatgaattat tagtaactaa tggtggtagt gaagctttac ttttcactat gatggcagtt
    51661 tgtgacccag gagataatct attagttcca gaaccattct atacaaacta caatggattt
    51721 ggtcaatctg taaacgtaga agttaatgct gttacaacaa aggcagaaaa cggtttccac
    51781 cttccatcta aagaagaaat attgtctaaa gtagatgata aaactaaggc tataattctt
    51841 tctaacccag gaaatccaac tggtgcaatt tatacaaaag aagaacttaa tatcctagct
    51901 gaaatagcta aagaaaaaga tttatggata atagcagatg aagtttatag agaatttgtt
    51961 tatgatgggc ttgagtatac aagctgtggt aacttagagg gtgtacagga tagagttata
    52021 ataatagaca gtgtttctaa gagatacagt gcttgtggtg ctagaattgg ttctatcgct
    52081 tgcaaaaata aaggtcttat cgctcaaatc cttaaattat gtcaaggaag actttgtgtt
    52141 cctacattag agcaaatagg agctgttgag ttatacaaaa ctcctgtttc ttacttcaaa
    52201 gaagttaatg aagagtacaa aaaaagaaga gatgtattat acaatgaatt aatgaaggtt
    52261 gaaggtgtta tatgtaaaaa accaactggt gctttctata tagttgctaa attaccagtt
    52321 gaaaatgcag aagatttcac aatttggatg ttaaaagaat ttaacaaaga taatgaaaca
    52381 gttatggttt gccctgctga aggattctat gctactccag gtttaggacg tgatgaaata
    52441 agattagctt acatcttaaa tgaaaaagac cttcatagag ctgctacatt attaaaagaa
    52501 ggtttagagc aatatgtagc tttacaaaaa taatttttta aacttaattt atataaattt
    52561 aatgatataa aatgtcccct tttcagatat tatttgaaaa ggggacattt cttaattaat
    52621 atattaatta agacttagac ctgactattt ttcattttct ttatatagtg ttggccagta
    52681 atctttattc actttaatta aagcatctaa aacttgtctt gccttagttg gagagattat
    52741 agttctattt aatgttaaag ataaaatagc tttttcataa gattgttcaa agtatgcatc
    52801 aactgctaac ttttcataag ctagttgacc ttctaacagt cccttataaa atgttggtat
    52861 attacctaca tgtaaaggtc tcggtccatt ctttgtaaga atcgcagcta cttctaccat
    52921 tgcatcatca ggtaagttgc taatagcccc attattttct gttataacta tggctatttg
    52981 gtgtttgtta tgagctattg cttctgcaac ttcaactata aattccccat gagcatcatt
    53041 atgcactaaa ttagaaccta tagatgttcc tttttctata acagatttac attcttcaaa
    53101 tacacgcttt tctcttccat tcataacttc tcttgctcta gtacaattta tatttgattt
    53161 agctactttt ttatcaggat atagataata ctgtacatat gtattaggta agtaatctgg
    53221 tacatcttcc aacatatctt taaccattcc ataagtgtct aaccaagatt tatctctttg
    53281 ttctgcatca acaggttgga atccagagtt tgctactaaa tcttttatct taggtaccaa
    53341 atcttcacca tttttatcat acaaatgtgt aaaccatcca aagtgattta atccaaagta
    53401 tacaggctca aatgttcttg aatccatgtc taacaatctt ccataagacc ttaacaagtt
    53461 aactggttgg tcacacatat taagtaatct tttatcatct ggaaatactc tttttaatgc
    53521 ttctgcaaca atagcagcag gatttgtata atttaatatc catgctttag gagagtattt
    53581 tcttacagtc ttaaccattt ctatcatatc acctatagac cttaacccat aagcaaatcc
    53641 accagctcca caagtttctt gaccaaccag tccaaattgt agaggaatct tttcatctaa
    53701 ttctcgcatc ttaagaccac cagttctcat ttgaacaaat acaaaatcta catctataaa
    53761 tgcttcatct gggtttgtag tatattcaag tgttgcttta ggatattctt ctttaaataa
    53821 tatttttcca aattccccta ttaatctttg acgttcttct actacatcta acatagttac
    53881 tttatttaga ggaaatctat cactcatttt acataaagac tttaaaagtc ctggagtcca
    53941 agtactgcct cctccaacta tagctatatt gtatcttttt ttcattgtca tattaatcac
    54001 ccctgttttt tattaactaa cttgtaagat gattataata tataaagttt tctacatgaa
    54061 tacttttagg taatcattaa aaatagttca attttagtat ttttttcaaa attgtaattt
    54121 ttttcatcta ttgtattttt caatgtattt atgaaacata tattccataa gagaaagtgc
    54181 tggcactcta gatgtatagt taacactatt aaaattatat tgtggagaag atacaaataa
    54241 ttttatatca gctatatttg ataatgaatt gacacttata tttgtcagag aaattacttt
    54301 aacttgattt gtttttgcta tattacatgc cttaataact tgagcagtct ctccagacat
    54361 agatacagca attacaaggt catctttagt aatatttgat gcagccaaat acatgagagt
    54421 tgaatcatca tagtatttta catttacacc tatagctgaa aaacgttgag acatttcagt
    54481 acatactaat ctagaagacc caacaccaaa aaaatatata tgcttagaat tatgtatttc
    54541 atttaaacac atatctatat tctctacatt tattaaattt tgtgtatcca taacatcagt
    54601 aaaaatatca ctttgacttt tagtaaactc cttatttctt tcatttctat ttgaatatga
    54661 aaaaactaaa aagtttttaa attcactata tccagaaaag ccgagcttct gacaaaacct
    54721 tactatgtat gcagtcgaat taaaagtttc atttgctata tctttaatct ttttttgatt
    54781 tattttttca gaatttttta gaaaatagtt taaaagagat atttcatttg tagataattt
    54841 tttttgattt atatctaatt tgtctattag gttcatttat acctccataa taatgatttg
    54901 tagttaaaca actttctcat atttattata taaatataca ctatacagca tttatcttat
    54961 gtttattata ctataaaaaa gacaatacaa attataaatt agtattgcct tttaatattt
    55021 actttaaata gacattgcaa aagaaacttc gtctcttact tgagatacag atggcccata
    55081 aattatttgg atatctttat cagatacttt tataactccc attgcacctg tatatttttt
    55141 aaaagcattt tcatctactt tactcatatc tttaactact actcttaagc gagttataca
    55201 gtttgttata tcttctatat tgtccttacc acctaaatat ttaattatag ataatgctct
    55261 cttagtagtt tctccacttt gagctatttc tactttattt gataaaggtt ttaaatcaaa
    55321 atttatatct gttatttctt ctcgtcctgg agtttgtaag ttaaatctaa gtatcaaaat
    55381 cttaaataca ttataataaa ctattgcata cactaaacca agtattatag aataaatcca
    55441 ctttgtattt ggttgcataa ctccaaatac tactaaatct attatgccac cttgagtatt
    55501 tcctattgct actccaaata tatgcatcat cataaatgat atacctgata aaaatgcatg
    55561 tataacaaat aatattggtg atacaaataa gaatgaaaat tccaatggtt ccgtaattcc
    55621 tgttacaaat gttgctaaag caccagctag taatatacct ttaaccttcg acctattttc
    55681 aggctttgca gttttataca tggcatatgc agcagcagga agaccaaata ccattatagg
    55741 tattttccct tgagctaaaa atctagttgc ttctgttgaa aaactgattg tttcagggtc
    55801 acttagttga gctaagaata tgttcaatgc tccaaatact tcttgccctc ccacaactaa
    55861 agaacctcct acttcagtaa atctaaacat agcatttaat atatgatgta atccaaatgg
    55921 tattaaaagt ctttcaagaa atccaaatac aaatgttcct aaatatccta aactagctat
    55981 accaatacct acactctgaa taattgtatt tacatatggc catatatatg gtattattat
    56041 ccccaaaata gagaatacta ctgttgttat tattggaaca aacctagttc caccaaagaa
    56101 tcctaaataa tctggcagtt ttatattata gtatttatta tgtaatgatg ctgttattat
    56161 accaactaca attccaccaa atactcctaa ttctaatgtt tgtatgccta aagttacagc
    56221 ttgacccatt tctctcatca tgtcaggttc agcaataatc cccctacacc ctaacatata
    56281 atttacacta gtgtgtaata ctaaataacc aacaaaacca gaaaatgcag aaactgcttt
    56341 ttcttcttta gcaagaccaa cagatattga tatagcaaag aatattgcta agtttccaaa
    56401 aagtactcct gttatagctt ttgtaaaacc caatattcct tgaataaaat tatttgctaa
    56461 aaaaggcata tcactaacta tattaggatt tgaaaatgct gaacttattc ctaaaaatat
    56521 acctgctgca gatattaatg ctattggcaa taaaaatgat tttcctaact gtaaaaagaa
    56581 ccctttcatt ttttgtttca tttctatccc tccattttta aatttttaaa acgttttcta
    56641 tgtcataatt atatattttt attttgtttt tgaaacttta taatttgttt taaaatattt
    56701 ttacataaat agtaattttt tcaaaactgt aaattttttc aaacaaagac atagtaacgt
    56761 tgtaacatat ataaatttaa aaagagctta gaaaataaaa ttattgaata taaaatggaa
    56821 aaatataaat tacacaaaga gatatgagta cgtactaaca aatacgaaaa tgtataagaa
    56881 attataaaaa agtacatcaa gaaaatttaa gatgtacttt ttagattgta tttagactta
    56941 taattatata gttaaatgaa taacaaagaa ttaatcttag tactattaaa tacaaaaatt
    57001 tttatatttt ttctatctaa attcttcttt gtttaatata tattgaagag tatttattgc
    57061 ttctaaatat ttttttctgt cttcttcagt taatttagaa agtttttctc ctaaaccatc
    57121 acttaattta tccataaaat cagttgctat cttatctccc tcttcagtaa tgtcaattag
    57181 atattttctt ctatcaacta aatctctttt ccttgttaca tacttcttat cagttaaatc
    57241 atcaaccata ctagttaaac tgcctttttc tatatttaac ttagagcata aatcagtcat
    57301 acttattact ccataatttt ttatgaaaac taatgctctt aattgtgttt tatttacatt
    57361 ataatctggt gcaaattttt ttaggtcttc taagtacagg ctagaataaa tcttaggaaa
    57421 tgtttttact aaaaaactta tggtatcttt tactatatag ttcatataat cacctcggtt
    57481 gttttaaaat ttattaaatt atctaaataa ctttatttca gtttacatta aaaatattgc
    57541 aagtacaata gtttttgctg aatgtttaaa tttaattagt aatcttatca tttttttatt
    57601 tttatttata ttattcctat taaatattat ttatatagct attttattaa attcatggta
    57661 tagtaagtaa agaagaactc ttcacagcgg tggagagaag acgctagccc attaaaatgg
    57721 ctatcttatt tataaataag atagccgttt ttaattatat tttatctgta caattctata
    57781 ctcttaagtc tacatctact tttcctaagt cttccttata atcttttata gcaggttcta
    57841 caacttcatt tacaaattct acaacttgtt ctggagctct acctataaag ttttttgggt
    57901 ccattataga tagtatttct tccttgctca ttttaaatga atcatcattc attataagtt
    57961 caattaagtt attatccttg ccttcatgct ttactctata ggcagctttc atagaatatt
    58021 ctcttattat ttcatgtaat tcctgtctat ctccacctct ttttacagct tccataagta
    58081 ttgtttctgt agccataaaa ggaagttctt catttacacg tctatttatc atattttcat
    58141 atactactaa accatcagtt acatttatcc ctatttcaag tatagcatct gctgccataa
    58201 atgcttgagg tattgccaat ctcttattgg ctgagtcatc taatgttctc tctaaccatt
    58261 gagtggcttg taccattgca gggcttatag attcagagat tatatactta gataaagatg
    58321 ctattctctc acttctcatt ggattcctct tataagccat tgctgatgaa cctatttgat
    58381 ttttttcaaa tggctcttct aattctttta aactttgtaa aagtcttata tcattagtca
    58441 tcttatgcat actttgagct atccctgata gtatgcttat tacttgataa tctaactttc
    58501 tagtatatgt ctgtccactt actgcatagg aagaatggta tcccatcttt ttacaaattt
    58561 tcttatctaa ctcttttact ttttcgtggt ctccttcaaa taagcttaaa aaacttgctt
    58621 gagtaccagt agtaccttta actcctctta acttcatgtt gtctattcta tagtttaaat
    58681 cttccaaatc aagaattaaa tcttgagccc ataaacaagc tctttttcct actgttgtaa
    58741 gttgagcagc ttggaagtgt gtaaatccaa gagctggcat atctttgtac ttaagtgcaa
    58801 attcttttaa attgtttatt aaatttacaa gctttactct tagaagtttt aaagcttcat
    58861 tcatttgtat aacatctgta ttatctccaa catatgcaga tgttgctcct aaatgtatta
    58921 ttcctttggc tttttcacat tgtaaaccat aagcttttac gtgagacatt acatcatgtc
    58981 ttacttcttt ttctattttt ctagcttcat caaaatttat attatctata ttagctctta
    59041 gctcatctaa ttgttcttca gttatattga ttcctaactc atgttcacct tctgcaagtg
    59101 caacccataa ccttctccat gtagagaatt taaattgtgg agaaaatata taactcatgt
    59161 ccttgctaca atatctgtct gtaagtgggt ttgagtaagt agtatattta ttatctatca
    59221 ttatattagc accttcctta aatcttttgt cgtgtgatta ctgtgtacac attagtacat
    59281 aaataattat atataatttt acgaactata acaagacttt tttatttttt gttcacattt
    59341 atatatagta ttttttattt attactattt tttatttata tccaaattat ctttttcaat
    59401 taagtaatcc actatttcac tatcaacaaa atttaataca tacttatatc taattgcata
    59461 gtatttatca ctccatccaa gctgattttt tacatcactt tcatctgccc caagccttaa
    59521 acttattgct gcaaatgaat gtctaaaatc tcttgctgaa tattgagaaa gtccagctaa
    59581 atctaatgct tttttgacta taagtctgac atttctatct gttatagaat tactcttttg
    59641 agttgtaaaa ataaaatcat cactaggtat tattacctct ggaagcccag aataattcct
    59701 gtaatcttct aaaagtttaa aaaagtatgg atgtaattta actactcttt cttttcttcc
    59761 cttacctaac cttacatatg agttatcgtt ttcatctacc ataaggtctt tccactttaa
    59821 gctaactaat tcatttaata aacacccagt agtaactaga cagactatta ttactctatc
    59881 tcttatattt aattttggta ggatacctat aagtttattt atttcttgta tacttagaac
    59941 atcatctttt gtttttattc ttgttactgt gggtttttct acatatctaa atggatttat
    60001 atctatgtat ccttcttttt ttaagaagtt ataaaaacta tgtaaataac tatatatctt
    60061 ttcacaagtt gatttcgcat atttagtctg tatatagtct acaaaatttt tacaatcttc
    60121 tttcgtagca taaatcaatt ctttcccttt taaaaattct ttaaacagta taacctttga
    60181 taaataatcg tgtttcgtgt ttggatttaa ttttgtagaa aaaacattaa aagtttcata
    60241 ctcataatca tctagtattt ttgtactata cataataact cctttccttt tcataaaata
    60301 aaatagctat acttttacta taccatatat ttccccctca aatatacccc ttattcaata
    60361 gataactttt aagtttattt tgttatattg tgaaggtttt atgaaaatat caatcttcca
    60421 ttgtgcacta cacagtacta tggtattata agttagtaaa aggtggcatt tttttattaa
    60481 tctatgaata aaatatgcta ctataaattt gtattggagg tattttgatt tggaaacatt
    60541 tagtttgctt gaaattttta aggcagtcat tttgggcata gttcagggaa taacagaatg
    60601 gctaccagta agtagtacag ggcatatgat attagttgat gagtttataa aattgaattt
    60661 ttcaaataca tttataagta catttttagt tgtaattcaa tttggttcaa tattagctgt
    60721 acttgttata ttttttagaa aattaaatcc ttttgatagc gcaaagaata ttaagcagaa
    60781 aaaagaaaca gtccgtttat ggcttaaggt tataattgca gttataccat ctggagttat
    60841 tggaatactg tttgaagatg atatagatag attattcttt aattcaacag tagttgctat
    60901 tgctcttatt gtatatggta taataatgat agggcttgaa aagagaaata aaaaacctaa
    60961 gtataaagat ttttctcaag ttacatataa attagctctt tgtataggat tattccagtg
    61021 tctagctctt ataccaggta catctaggtc tggttctact ataataggtg cagtattact
    61081 tggtacttct agatatgtag cagcagagtt ttcattcttc ttagccatcc ctacaatgct
    61141 tggagctagt gcattaaaac ttctaaaagc tggatttgga tttactggat ttgaatggct
    61201 tattttaggt gttggttctg tagtagcatt tgttgtttca attgtagtta ttaaattttt
    61261 tatggactat atcaaaaaac atgacttcaa agtatttggt tattatagaa tagtcttggg
    61321 tatagtggtt cttgcttatt tctttctatt ataatgtatt ctaatttaat aacaaatgat
    61381 aaggagaaaa gttatgagtg ttaaaaaaga aatatttgat tggattaagt caatagctat
    61441 ggctattgta cttgcatttg taattctaca atttataaga ccttctattg taagtggaga
    61501 atcaatgtat cctactttag atgataaaga ttatctgatt ttaaatagga tatcatacaa
    61561 ggttggtaaa cctgaaaaag gcgatattgt agtttttaaa accaatttag ttgatggaga
    61621 aacaggaaag aaaaaagact taataaaaag agttatagct actgaaggtg acagaataaa
    61681 aatatcaaat tctaaagtgt atgtaaatgg aaaattatta aatgaaccat atatacacaa
    61741 taactatact tctggagata tagatactgt tgttccaaaa ggtaaactat ttgcaatggg
    61801 agataataga gaaaatagta atgatagtag attccctgat gtaggtatgg ttgatgaaga
    61861 tgaagttctt ggtaaggtta tggtgagact attacctctt gataatattg ggaaagtaga
    61921 ctaaaaaata agagactgaa ttggtaaagt ttattttaca aatctcagtc tctttttatt
    61981 ttcttaaatt acaaatattt ttttactaaa tatcttttga ttctgtaata agtcttatta
    62041 tatcacttgc ttcttcatta aaagttgtta ctatacttag gtagtctgtt gctctactca
    62101 tagctaaata aaccttattt aaatctccta caaagtcatt tacttgataa tcttgttcaa
    62161 tatcatttat agtttgattg tataacatct ctaattcaca tactattacc gctttatact
    62221 ctaaattctt tattgcatat atatttgcta ttgtagttcc taccttctta cttatatttg
    62281 tcaaattatc ttctgcacat atataaggaa tttttgcctc ttccaatgct ttttttaaca
    62341 tatattgaaa gtaaatggtt tttccacttt ttaatttctt cttattgtaa ggataaacga
    62401 tagcaacttc agaataatca agaccttttt tacttattaa atactcaatt tcccagatta
    62461 cagaacttat ttggtcatca aggtcactta cttttattat atcaacagac ttatttccac
    62521 ctctaagtgc tttagtataa aagaaagtac taaattctgt atttggtctt aattcgttga
    62581 tatatgagtt agaattattt gaaaatttat ttgtaaaatc tacaatctct ttagcttgtc
    62641 tataattttt acttaagata atcttatcat caaattctat accattatat aattttttaa
    62701 atatattcaa tctattagag atattcaagg agttacaaga acacacatta aatatgaatt
    62761 ttgttttata taaaaactcc cttataaaat ctatttcata ctctaaaaag ctttctgctt
    62821 catcaataaa aatagccttg aacatatttt tattttttat aatgttctgt gcttgtttta
    62881 caagattatt aaaggtcttt tcgtaatcat tttttaacat gttataatct acaattaaat
    62941 tgaatttttt agctagttta aatataaaag aactaaatgt gtgaacttct aaattgttat
    63001 tatctttgta taataactct atcctctctc gaagctcatt gcacaattgt tttgtatgtg
    63061 taaatatgac taatttatga tgtggatata cttttgctaa ttttatagcc ctagaaagca
    63121 taattgctgt tttgcctata ccagaaccac cttcaataag tgtattccca tatttaatag
    63181 aaacaacatc tttaatttga acgtcttcca tcatagttgc tgtatactta tagtcatcat
    63241 tgtagaatga aattttttta aatttttcat ttagatgaag tttatcattt attatatagt
    63301 attctgaaca tatgtctagt aaaaataaat ttaagtttat ttcatcattc tcatcattaa
    63361 gatattcctc cagcgaaccc ttattcatta tatcttgaag cttattttta tctattatat
    63421 tattattaac aaattcttca aattcatatg tttcctcaac ttcaacgtat ggcataatgt
    63481 aaacgtagtt ataacttata tttctattct tttgtcccat ttttagtttc aaaagttcat
    63541 attcctcatt cataacttca agtaactctt cttctaaaat aaaaaatata tcttctgttg
    63601 tatccataaa ttttataaat aaaattcttc catctttaac atacaacaaa tcggtattta
    63661 ttcctttaaa aggagtaact tttggcacta ctttaacgtc ctcattgata ttttcgtaaa
    63721 atattttctc gaactccttc aattttaggg cgtctaactg agaatttata tttatgtatt
    63781 ggctcactta cattacctcc ttctgttata cttaattata ccattttgaa ctatattttt
    63841 atatatactt tttataggca aatttagtaa ataaattcaa aataaataca aataaataca
    63901 aaactgctaa aaaaattt
//
LOCUS       DAGQVA010000014        61397 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.014, whole genome shotgun sequence.
ACCESSION   DAGQVA010000014 DAGQVA010000000
VERSION     DAGQVA010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.014"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(211..1056)
                     /locus_tag="MIV85_001038"
     CDS             complement(211..1056)
                     /locus_tag="MIV85_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960406.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(1086..1457)
                     /locus_tag="MIV85_001039"
     CDS             complement(1086..1457)
                     /locus_tag="MIV85_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBY2960407.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(1610..1870)
                     /locus_tag="MIV85_001040"
     CDS             complement(1610..1870)
                     /locus_tag="MIV85_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBY2960408.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(2059..3003)
                     /locus_tag="MIV85_001041"
     CDS             complement(2059..3003)
                     /locus_tag="MIV85_001041"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBY2960409.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(3024..3878)
                     /locus_tag="MIV85_001042"
     CDS             complement(3024..3878)
                     /locus_tag="MIV85_001042"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBY2960410.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKLLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(3893..5254)
                     /gene="accC"
                     /locus_tag="MIV85_001043"
     CDS             complement(3893..5254)
                     /gene="accC"
                     /locus_tag="MIV85_001043"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBY2960411.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(5270..5722)
                     /gene="accB"
                     /locus_tag="MIV85_001044"
     CDS             complement(5270..5722)
                     /gene="accB"
                     /locus_tag="MIV85_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBY2960412.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(5992..6438)
                     /locus_tag="MIV85_001045"
     CDS             complement(5992..6438)
                     /locus_tag="MIV85_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960413.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            6713..6991
                     /locus_tag="MIV85_001046"
     CDS             6713..6991
                     /locus_tag="MIV85_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960414.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(7120..7866)
                     /locus_tag="MIV85_001047"
     CDS             complement(7120..7866)
                     /locus_tag="MIV85_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960415.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEI
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(7995..8639)
                     /gene="trmB"
                     /locus_tag="MIV85_001048"
     CDS             complement(7995..8639)
                     /gene="trmB"
                     /locus_tag="MIV85_001048"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBY2960416.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(8777..9097)
                     /locus_tag="MIV85_001049"
     CDS             complement(8777..9097)
                     /locus_tag="MIV85_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBY2960417.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(9550..9798)
                     /locus_tag="MIV85_001050"
     CDS             complement(9550..9798)
                     /locus_tag="MIV85_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBY2960418.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(9829..10290)
                     /locus_tag="MIV85_001051"
     CDS             complement(9829..10290)
                     /locus_tag="MIV85_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBY2960419.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(10328..11161)
                     /locus_tag="MIV85_001052"
     CDS             complement(10328..11161)
                     /locus_tag="MIV85_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960420.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(11435..12121)
                     /locus_tag="MIV85_001053"
     CDS             complement(11435..12121)
                     /locus_tag="MIV85_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960421.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(12136..14613)
                     /locus_tag="MIV85_001054"
     CDS             complement(12136..14613)
                     /locus_tag="MIV85_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBY2960422.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSKELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(14832..16235)
                     /locus_tag="MIV85_001055"
     CDS             complement(14832..16235)
                     /locus_tag="MIV85_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960423.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            16728..17588
                     /locus_tag="MIV85_001056"
     CDS             16728..17588
                     /locus_tag="MIV85_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBY2960424.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(17827..18384)
                     /locus_tag="MIV85_001057"
     CDS             complement(17827..18384)
                     /locus_tag="MIV85_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2960425.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(18574..19461)
                     /locus_tag="MIV85_001058"
     CDS             complement(18574..19461)
                     /locus_tag="MIV85_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2960426.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            19580..20779
                     /locus_tag="MIV85_001059"
     CDS             19580..20779
                     /locus_tag="MIV85_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBY2960427.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(20973..23528)
                     /locus_tag="MIV85_001060"
     CDS             complement(20973..23528)
                     /locus_tag="MIV85_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBY2960428.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWSLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(23525..24211)
                     /locus_tag="MIV85_001061"
     CDS             complement(23525..24211)
                     /locus_tag="MIV85_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960429.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGELL"
     gene            complement(24288..25196)
                     /locus_tag="MIV85_001062"
     CDS             complement(24288..25196)
                     /locus_tag="MIV85_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960430.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(25198..25869)
                     /locus_tag="MIV85_001063"
     CDS             complement(25198..25869)
                     /locus_tag="MIV85_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960431.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            26131..27195
                     /locus_tag="MIV85_001064"
     CDS             26131..27195
                     /locus_tag="MIV85_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBY2960432.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            27353..28039
                     /locus_tag="MIV85_001065"
     CDS             27353..28039
                     /locus_tag="MIV85_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960433.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYKDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            28029..29060
                     /locus_tag="MIV85_001066"
     CDS             28029..29060
                     /locus_tag="MIV85_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960434.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLL
                     IYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            29142..29807
                     /locus_tag="MIV85_001067"
     CDS             29142..29807
                     /locus_tag="MIV85_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960435.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            29820..32237
                     /locus_tag="MIV85_001068"
     CDS             29820..32237
                     /locus_tag="MIV85_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960436.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSST
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(32418..33209)
                     /locus_tag="MIV85_001069"
     CDS             complement(32418..33209)
                     /locus_tag="MIV85_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBY2960437.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(33242..33829)
                     /locus_tag="MIV85_001070"
     CDS             complement(33242..33829)
                     /locus_tag="MIV85_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2960438.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(34006..35397)
                     /locus_tag="MIV85_001071"
     CDS             complement(34006..35397)
                     /locus_tag="MIV85_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBY2960439.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(35587..36885)
                     /locus_tag="MIV85_001072"
     CDS             complement(35587..36885)
                     /locus_tag="MIV85_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBY2960440.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKDIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGYPLPIPYIMPLKETLCMS
                     MSRGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(37242..38117)
                     /locus_tag="MIV85_001073"
     CDS             complement(37242..38117)
                     /locus_tag="MIV85_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBY2960441.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(38310..38996)
                     /locus_tag="MIV85_001074"
     CDS             complement(38310..38996)
                     /locus_tag="MIV85_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBY2960442.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(39045..39578)
                     /locus_tag="MIV85_001075"
     CDS             complement(39045..39578)
                     /locus_tag="MIV85_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBY2960443.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(39622..40254)
                     /locus_tag="MIV85_001076"
     CDS             complement(39622..40254)
                     /locus_tag="MIV85_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBY2960444.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(40344..41423)
                     /locus_tag="MIV85_001077"
     CDS             complement(40344..41423)
                     /locus_tag="MIV85_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBY2960445.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(41556..42902)
                     /gene="pepV"
                     /locus_tag="MIV85_001078"
     CDS             complement(41556..42902)
                     /gene="pepV"
                     /locus_tag="MIV85_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBY2960446.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(42971..44251)
                     /locus_tag="MIV85_001079"
     CDS             complement(42971..44251)
                     /locus_tag="MIV85_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBY2960447.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(44378..44638)
                     /gene="hfq"
                     /locus_tag="MIV85_001080"
     CDS             complement(44378..44638)
                     /gene="hfq"
                     /locus_tag="MIV85_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBY2960448.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(44752..45687)
                     /gene="miaA"
                     /locus_tag="MIV85_001081"
     CDS             complement(44752..45687)
                     /gene="miaA"
                     /locus_tag="MIV85_001081"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBY2960449.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEAKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(45725..47692)
                     /gene="mutL"
                     /locus_tag="MIV85_001082"
     CDS             complement(45725..47692)
                     /gene="mutL"
                     /locus_tag="MIV85_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBY2960450.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYFVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNIDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(47703..50546)
                     /gene="mutS"
                     /locus_tag="MIV85_001083"
     CDS             complement(47703..50546)
                     /gene="mutS"
                     /locus_tag="MIV85_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBY2960451.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(50707..51441)
                     /locus_tag="MIV85_001084"
     CDS             complement(50707..51441)
                     /locus_tag="MIV85_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960452.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(51410..52423)
                     /locus_tag="MIV85_001085"
     CDS             complement(51410..52423)
                     /locus_tag="MIV85_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2960453.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKNNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(52445..53215)
                     /locus_tag="MIV85_001086"
     CDS             complement(52445..53215)
                     /locus_tag="MIV85_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960454.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSIHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(53190..53480)
                     /locus_tag="MIV85_001087"
     CDS             complement(53190..53480)
                     /locus_tag="MIV85_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBY2960455.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(53611..53710)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      54330..54419
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            54472..54648
                     /locus_tag="MIV85_001088"
     CDS             54472..54648
                     /locus_tag="MIV85_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960456.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(54763..55119)
                     /locus_tag="MIV85_001089"
     CDS             complement(54763..55119)
                     /locus_tag="MIV85_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960457.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            55375..56288
                     /locus_tag="MIV85_001090"
                     /pseudo
     CDS             55375..56288
                     /locus_tag="MIV85_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
     gene            56519..57130
                     /locus_tag="MIV85_001091"
     CDS             56519..57130
                     /locus_tag="MIV85_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBY2960458.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            57428..57766
                     /locus_tag="MIV85_001092"
     CDS             57428..57766
                     /locus_tag="MIV85_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBY2960459.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(58173..59609)
                     /gene="miaB"
                     /locus_tag="MIV85_001093"
     CDS             complement(58173..59609)
                     /gene="miaB"
                     /locus_tag="MIV85_001093"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBY2960460.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(59857..61317)
                     /locus_tag="MIV85_001094"
     CDS             complement(59857..61317)
                     /locus_tag="MIV85_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBY2960461.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAYKTAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSA
                     RLKNVSKVYIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVN
                     TVMLTNAYKGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTL
                     VNNTKSTRLGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLV
                     NDGSNKSILKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGM
                     YKVGKDISAGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYI
                     KIEDSTMTLAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLG
                     NAEGIVTNDTFSGRRYITVEEDQYLILNDCYLIENE"
BASE COUNT        20981 a         9620 c         6915 g        23881 t
ORIGIN      
        1 gcagtgcttt agatgaaatt atcactaact attccctaaa tccacattta aagactagtt
       61 gaatttaagt actctttttt atttctcaat atatttatag aaatatttta aaatatattg
      121 agaaattttt tatgctctac taaaatcttt tttatataat atttttatat gtttctaacg
      181 aaaccaaata ttagtaaaat atgtatttat ttaactaaag tttttaaatg ggctgactaa
      241 gcttaaaata taggatatta tgagagttac tattgaaaaa ataaacccta ttgccataaa
      301 gaaacttata aatatgttat acttaactat taaactggat atattcaagt tatcaaatcc
      361 aaataagtat gtaattgaac ttattacaaa aataactata actataaagc tcagaccatt
      421 taagctattt tttaaatcag cactactaag tgacatatgt gtagatatag aatacattaa
      481 aaacataaat ataaaatact tcaatgaata tacactaggt gttaacaaca ttattcttat
      541 aaaattggaa atatcaccta aaataatgtg tataaaccca tttatattta aattattaat
      601 catacttaca tataacttta aatctatatt ttgagtcact ttcatataac tatctggcag
      661 taatatctta aaaattaaaa taatcattat tgttccacct ataataggtg caattcctat
      721 aaagaaattt cctatacttt gataaagatt atctttttta tagctatgac ttacatatcc
      781 tagtatacca tcatttttac tttctattgg tctgaaaaac ttaactgaat ttattttatg
      841 catgaaaatt aaacacatta tcaaatgact caattcatga acaaacgttc ctatagctcc
      901 agttacaata attccagttt ttccaaaaga tgaaaatata aatttattat ttagattttc
      961 tgtaatgcta aaaatcaatc caaatacaat aaatattcct atgaaacaaa aaatatttat
     1021 tacacttatt tttaaaattt cgattatata aatcataagt taagtcctca tgtaaaagta
     1081 tttaactact ctacttcata tccattacag cttaaaattt tacaagcatt ttctatatct
     1141 ttttctttta ctaagatata gtctgtatca taagtagaaa ttgcaaatat gcttattttg
     1201 ttgtctgcta acaaactact taacttagat aaaattccta caagtgaaaa gtctaaagga
     1261 cctagtatct taagtattct ccactccttt tctgacttga catcagaagg aatattatta
     1321 tttaaacata caacacttaa ttcatcatca gttctagtta tagagtaaaa cttctctgta
     1381 tctatccatg ttggtatttt actgtcatta tttaatctac atactgcata ctcttctacc
     1441 aataatttta atttcataat gtatatttcc tccaatctta tttgtttact taagattata
     1501 cattaaaagt tacataaaat aaaacatata aagtaaaaaa ggttcactat agtgtcctat
     1561 ttctatagcc aacctttaaa acttaattaa attctaataa agagatatat tatctaggtt
     1621 caattataag tttaatggct gttttcttat caccttcgat ttctatatca gtaaatgcgg
     1681 gaatgcaaac taaatccatt ccactaggtg caacaaaacc tcttgctatt gcaattgatt
     1741 ttatcgcttg atttagagct ccagctccta tagcttgtat ttctgcaacg cctcgttctc
     1801 ttagtactcc agccaaggct ccagctacag aattaggatt agattttgat gaaactttta
     1861 gtacctccat ttcaacatct ccttgttaat ttgttaaagt atccattacc taaagtacta
     1921 aatcataatt gccatttact aattacaatc atcatttaaa gtatactttt ataaaaatat
     1981 acttctataa tcgttttaag aaaaccttta ttttttttaa ccattttatt atgaaaaaac
     2041 tacaaatttc tttatattct ataagcattt tccaatattt ctaaattttt tatatctttg
     2101 agctataatt tcctctttat ccatatcttt gtaatgattt aatctttcta aaatataagc
     2161 ttttatttct tttgaaacag cttctacatc tttttgtgct cctccaagag gttcttttat
     2221 aatcttatct attattttta aatcatataa atcattactt gtaagcttca taacatcaca
     2281 agcttcttta gctttagatg aatctttaaa tagaatacta gaaagtcctt ctggagaaat
     2341 tacagaataa actgaatgtt ctaacataca tacatcattt cctactccga tacctaaagc
     2401 tcctccacta ccaccttcac caattacaaa agtgattact ggaacagaaa gtttactcat
     2461 ttcaagtaag tttcttgcaa tagcttctcc ttgtcctctt tcttctgctt ctagaccaca
     2521 aaaagctcct gatgtatcaa taaacgttat tataggtcta ttaaattttt cagcttgttt
     2581 cataagtctt aatgcttttc tgtatccttc tggatgaggc attccaaaat ttctttttat
     2641 attttctttt gtatctcttc ctttttggtg tccaactata gtaacattaa actttcctat
     2701 ctgaccaatt cctccaacca tagaagggtc atctttaaaa agcctatctc catgaagttc
     2761 taaaaaatta gaacaaatat gttctatgta ttccaatgtc gtaggtctct ttatatctct
     2821 acttaatgtt accttttcat atgctgatag atgtgaaaaa gcatcttcct taagcttttc
     2881 caatttctca ttaagtgaat ttattttatc acttaaatct atattatttg ccttagaaat
     2941 agttattaat tgtttaatat cattttctaa gacttttatt ttttcactat tattttcaat
     3001 caaaacagtt cctcctttat gccctatttc ttgtgcatag caagaatttg atataatact
     3061 tccttcattt ttcttctatc tactatcatg tcaataaaac ctttttcaag taaaaactca
     3121 gaagtttgaa atccttcagg aagtttttga tttattgttt gctctattac tcttggacct
     3181 gcaaaaccta tcaacgtatt tggctcagaa attataatat caccaagcat agcaaaacta
     3241 gcagttactc ctccagtagt agggtcagtt agaactgata tatatggcaa taatttttct
     3301 tcaagcttag aaagtgcttg agaagtcttt gccatctgca taagagatac cataccttct
     3361 tgcattctag ctcctcctga agcagaacaa ataattatag gtaaattatt ttcagcagca
     3421 tactctattg aataagttat tttttcccca acaatagaac ccatacttcc catcataaaa
     3481 tcaggattca ttacacaaat aactgtttta attccattta ttcttccata acctgtgaca
     3541 acagcttctg actcttttgt tttttcctta taagagtcta ctttttcttt gtatttagga
     3601 aaatttagtg gattttgaaa ttctacatca gaattaaact ccataaaagt tcctttatca
     3661 atcaataaat ttattctttt tcttgctctt aagccataat gtcttgaaca ttttggacat
     3721 acaaatgaat tttcttctat gtcctttcta aatacatgac tatcacaacc tttgcaatag
     3781 gtccaaaatt tatcatctac actattcttt ttaaagttgt catctaaaga aatcgtaaca
     3841 tacttagatt cttttgatga taaaaatttt tttatcataa tctatttact ccttataatg
     3901 tagcaaattc tttcttcata aagacatctt ctataaattt ggtatgatga gtatcttctc
     3961 taaactcctc acttgttaca agtgcctttt gaaattctac atttgtatta ataccttcta
     4021 caataatttc gtctagagct ctatatattc tacttataca ttcttctcta gtttcagccc
     4081 aacatattaa cttacctatc atagaatcat ataaaggtgg tatagtatat cctgcatata
     4141 caaaagtatc aaatctaaca ccaaaacctc caggtaaatt taatgattct atcttacctg
     4201 gtgatggagc aaaattcttt gatgaatctt ctgcatttat tctacattca atagcatgac
     4261 ctctaaaagt aatatcttct tgtttaaaag gaattttatc cccattagct atagatattt
     4321 gaagttttat aaggtcaaga tttgttacca tctctgtaac tggatgttca acttgtattc
     4381 ttgtattcat ctctataaaa taaaagtttt tatctttgtc aactataaac tcaatagtac
     4441 ctgcaccgat ataacctact ccttttacta tatctactgc aattttatga agtttttgtc
     4501 tttcttcatc tgaaaggtat ggacttaaag attcttctat tactttttga tttcgccttt
     4561 gcatagaaca atctctatca cctaaatgta ttgcatttga atgtttatct ccaaatactt
     4621 gtacttctat atgtctagga ttttctataa acttttccat atataaatca ctattagaaa
     4681 atgctgctag agcttctgaa cttgccatat caaaatttga aaaaagttct tcttcttttc
     4741 taacgattct catacctttt ccaccgcctc cacttgaggc ttttatcata acaggatatc
     4801 caatttctct tgcaacttct aaagcttctt ccttagtttt caaaacagat tctgaaccag
     4861 gaacaacagg gatattcaat tccatcatag tttctcttgc tctagattta tctcccatca
     4921 aaatcatttg ttctcttgtt ggacctataa aaataatatt attatcttca cattgctttg
     4981 caaattcagg attctctgat aaaaatccaa agcctggatg aatagcatca cactttaatt
     5041 taagagcaag atagattata ttttctatat tattataact cttacttata ttatttggtc
     5101 ctatacaaat agattcatca gctatatatc tatgaaaaca atctttatct atttcagaat
     5161 agatagcaac agtttttata cctagttctt tacatgttct gatgattcta actgctatat
     5221 cgcctctatt tgcaactagt atttttttta tcaacttaaa tacctcctac tacaatggtt
     5281 ttatcttaaa taaaggttga ttatattcta ctagttcttc attactaact aatacttcaa
     5341 ttatttcacc tttaatttca cttgttatct cattcataag cttcattgct tctaatatac
     5401 ataaagtgtc gccttcttca actacatcgc caactttaac aaagctatct gcatctggac
     5461 ttggagaatc atagaatgtt cccatcaaag gagctactac tactgataga ttctcattag
     5521 atgtgacagg tgtatcgttt acaactggct tttctaaaga aagatccact actgattctt
     5581 gttgtacact taaaacaggt gaacttgtag attgagcttt tttagatact tctaatctta
     5641 aatcgctact ttcaagtttt acatattcta agttagttga gtctatggcc tttaataatt
     5701 ccttaatttc attgatgttc attttgttac ccccttgtat tattacctgg tgctaatatt
     5761 atatcacaaa aaacaaattt ataaaagaaa aagtgctgac tagagaatca acacatcaat
     5821 atatctttta attttaaatt aacaaccagt aacttatatt tgttttaatt ttccattatt
     5881 aatataaatt ataagtataa aatgaataaa attcaatatt ttttgcaaaa tacaagagaa
     5941 tacaaattaa tacctcggga atttttaaga caaataccaa tattatgcaa tttagacttc
     6001 gctttctttc aaattagtat cattttcttt atttttacat aggatgtact ttaatttagc
     6061 tatcaaaaca ttgctatata ggttaaaagt tattagaatt gcaggaatta taaagtaaac
     6121 tctagcacct ataaaaccaa aaactactgt aataagtatt aatcttttat ttaaagtaaa
     6181 aaaaggtata ttaaaaatac ttttgtcgga tgtttctgga gtataagaat atataactcc
     6241 aaaaatcaaa gtaagcatac aaagtggaag tagtgtataa cttgaaatta ttcccagaaa
     6301 tcctatactt tcaaaatatt tgctagcact atttgtataa acaaacatgt atccatttaa
     6361 atatgcgcat atacatgata taatgccaaa agttccccct aaggattgag tgtaccaatt
     6421 aaaaaattta gattccatat acctcacctc ctaaaactgt atatataatg atatgcattt
     6481 aaatagtaaa atatatcttt atatgtttct gaataaaatt ttgttaattt cattaattta
     6541 tgtttaagaa atttgaagta tagtgtagta tatattaatg tagatgaagt tttatagtac
     6601 ttatttcata gtgcttaatc aagttatctt attatggatt caaaagttgt ttgtagggtt
     6661 ttatattttg ttgagctgaa aaatttatta taaatgaagg gatgttttcg ctttggtaga
     6721 tacattagaa tttggtctta aaattttatt ttttatatta tcaataattt ggatgggtaa
     6781 aataatgatt ttaagaactg ataagcaaat agtaatcaat cctttgctta ttggtatatc
     6841 tgcagtcctt gtgatgttgc atacctcaca gagtaacatt gaattttttg gattagatgt
     6901 ccaatatata agaatagttt tgtatataat atattcactg ataattttaa taggaatatg
     6961 ggctactaac agaagaaatg gaatttttta gataatctat ttctataaaa tttaaaggtt
     7021 gctagtaaca aagcactaat attagcgttc tgttactaac aacctttatt ttgattatac
     7081 acttaaattg aaaatagaat gattgaataa gttgacagat tattttacat tgacagtaat
     7141 tagaacttct tgagatgtat ttaaatcatt tttgtcgctt agtataactt ttaccactgc
     7201 ttgacctgtt ttattacctt taattatcat atcttcacat gaaagtacac tcttatcact
     7261 tacagataca ataaaattta aatcttttgg aaggttatca gtaacttccc agtatttata
     7321 ataactatca attttcttcg taattatttt tctcaaatca atactttcac cttttgctat
     7381 atcaacgtta tgatatttag agtccagttt atactgatta tcttttgtat caataaaatt
     7441 taaatcgcaa tttacatcca caccattatg agaaagagaa tttactacat cgtcatcaat
     7501 caaataatta ttggcaagat ttattgaatc catatctttt agacttaaag cttccttagg
     7561 aatctctttt atattattat tccaaaaaat aaaattgtct acattttcaa gatatgatat
     7621 accttttaaa tttgaaatgc tctcaccagt tgcataaaat tctccatcta aagcctttat
     7681 attgcttata gtcatctcat ctggatttat atatcttttt acaactgctc ttaaatttgc
     7741 atcaggaaaa atatctttaa gttgattttc gctcaaaacc ttatcatttg aatttattgg
     7801 acttaaagct gctgcagaaa taataaatgg tattaaatta gctaaattca tagtaccctc
     7861 ccacataaat tttttattat aataatttaa tttctatgag agggttctgt ttccttgtta
     7921 tatataccta ctttcgtaca ctttattaat ataaattaaa ataaatttct actattaaac
     7981 ttataaacat attactagtt acgtttttta gcttcacatc taaatattcg cataccttgt
     8041 gacataaatt tgtcttcata ctctgttgta acattatttt catactcact atttcctaaa
     8101 tcaagagaaa tattctttaa tagccaatta tttgcagcaa tttcatttaa actaaactcg
     8161 aataattttt cattatctgt tttaaagtga atttcgccat catcttccaa aaccctattg
     8221 tacatttcta aaaatccaga atgagtgagt cttcttttac tccatctatt tttaggccat
     8281 gggtcacaga aatttatata aattctcgat aattctttag cttcaaagta atccaaaata
     8341 ttgcttacat ctccccataa aaatagtata ttattcaaat tagaagcatc tgctttttca
     8401 acagccttta aaagaacttc ttccttaagt tccatggcaa tataatttat gtcagggttc
     8461 tgcttagcta aagttgttat aaacttacct tttccagtcc caaattcaac atgtattgga
     8521 ttatcatttc taaactttaa attccacttg ccttttaatt tgtctatatc gtctcttaaa
     8581 acatattttg tataacttaa aagcttttca tctgcacctt tttttcgtct tcttctcaca
     8641 ataattctcc ttacatataa aaaattagta aaatacattt ttattataca ttatctcacc
     8701 aaaaaataaa aagaactctc ttaaaataga aatttatttc tataaagaga gttctaaact
     8761 tactaaaaac ttaatcttag tggcaccctg aacaaccaga gcatcctcct ccaccttgat
     8821 ctttcatatt ttcaggaata actctaaatc caaatcctgt atcttctatt attatatctc
     8881 catactgact atattcatca gagctcatta caaattgtaa ttctccaact tcataagtta
     8941 agtcatcttc ttttttctca tctaaagcta atccaaaaga aggacctcca caaccaacac
     9001 ctgcaaagta tactcttata ttattaggtt tatcttgatt gtcttttaag atacttttta
     9061 aagtatcaat agctgtttct ggtaaagtaa ttttcatcaa atcattccct ttcaaatatt
     9121 ttattaaaac aatatctatt atatacccat acaaggtaca taatcaatta gtttttgcat
     9181 attttactaa aacttctacc taatattacc taaggcttta aaatatttta tataatattt
     9241 tattacctta aataaatacc ctatcataaa cttagtaaac aaataaaatt attattctaa
     9301 aaaatataat aattttattt gttgttttaa tattataaca catttgataa tgtccaattc
     9361 atatatgcaa aatttatata ctttaaaata tctaagaaat tattcaataa aaaaatacta
     9421 ttttttaaaa attatcatta ttgataaagc tctactattt atatttttta gtgtattcat
     9481 gtataataag taaaagcaca acggtatata ctgttgtgct tttttgtaat taataaacaa
     9541 tattttggtc tataacaatg aaaaatggct actttccata attgatttca tctgacataa
     9601 gcaaaaaggg tgtccagctg ggtcaatcat aactctccag tcatcagtaa attgctcctc
     9661 tgcgattgta gctccacaat gaattgcata ttgaactgct tcttctaaat cattaacagc
     9721 gaaatccata tgagccattt gctgttgaga ttcaggtttt tctggttcta ttatgcccca
     9781 agcctttgtt ttttgcaata taaagaaaaa attatatatt ttaatatttt ataattgttg
     9841 aaattgtgta ataaattcaa ctggatacat agtgcgtttt gaaatttctt ctaaagctaa
     9901 accttgtttt aaaagcctct ttatgacgct ttccatactt tctgaaattt ctataatatt
     9961 tttatcaaaa tcataaaacc taaaagttct ttgaccccat gggtattctt ttatataatg
    10021 caaaaattca atatttccta ttctatttat cttactttcc cattgtttga tgtcattaac
    10081 ctcaaaatac aactgaaagt tatttgattg ttgatatatt ggtaaatcat atccaattat
    10141 agctttataa ttactttgta atccaaatcc attttcaaat gatacatgtt ctcctaaatc
    10201 taatgtgatt ttttgctcca taacatcttc ataaaacttt tttgatttat ttatgtcttt
    10261 gacaattagc aatactcctc caaatttcat cttatcacta tcctttcttt gttataagta
    10321 ttataactta aaattttgca atttcactgt aaaaatcaga catattagct cggtattttt
    10381 gaggagttat tccacagaca attttaaaat ctttaataaa atgtggtata tcatagaatc
    10441 ctaattcatt acatatagac atcaatgaag ttttattatt gtttagaagt tttatagatt
    10501 tattaatacg taccaaacga gaaaatgact tcatactcaa ccctaggtac tgattaaaga
    10561 gtctgtttaa atgcctagaa ctataaaata cttttttaga aatttcttgt gaagatatat
    10621 ttccagagtt ttgaataatc aactgaattg ccaaaataaa ctcatatgag tattcaattt
    10681 taatattaga aatcaataat tcttccaact ttaaaatcaa tttatctata gataaagatt
    10741 cattaaatat ttttttaatt tctaaatcta atgaagtatt aattatagaa aatggaacaa
    10801 ctttatcaat aagttcactt tgctgtatac ctataagcgg gaaaaaacca gcaggttgaa
    10861 attctataat tagtataaca tcacatctat tagcaatatt tcctactgtt tttggtttag
    10921 tagttggacc aaataataga ctatgtaacc ctgtggcatc ataaaaaaac accaaagtta
    10981 cacttccatg aggaataatc gtgtaattat cagaaattat tgtttgattt ggaaacgata
    11041 tagtaaaatt cgatatccaa tttcttaatt gtatacaagg caagagataa acaaaattgt
    11101 cttcacaaac tataagtgac ctatttttat ttataaaatg aatactttct ttttttaaca
    11161 tatattatat cctgtcctat cgtgaatatt tattaaagta agaagaatcc atattatctc
    11221 tatatatcat taactgcttt taataataga gatagtatga atactcatta gatatttaat
    11281 aaacaaataa aattaaaata atcaataaaa aatatagtac ttttatctgt tattttaata
    11341 ttatagcaca tttatagtat ttaacttata tccactttac atatgtctaa tttatataat
    11401 taaaaatgct tatctcaaat acaataatta gtccttatac aattaaacca tctgaaactg
    11461 taatagtacg actactactt ttggctgctt ctggtgagtg agttaccata attatagttt
    11521 gtccattgtc tctgtttatt ttattcagta aatctattat ttctatccct gttttactat
    11581 ctaaatttcc agtaggctca tcagcaaata gaatctctgg ttttccaatt aaagctcgag
    11641 ctatagcaac acgttgttgc tgaccaccag ataactctcg tggtgtatgt ttacgtctat
    11701 cagttaaacc aactatatct aagatttcat ctaattgatt tttataatct tttaaatttt
    11761 taccatctaa taacaaagga agcattatat tttcctccac atttaaattt ggtattaagt
    11821 tataaaattg aaatacgaat cctatatttc tacgacgtat tatgctcatt ttctcatcat
    11881 taaaatgtga tatatcagct ccattcatat acacttttcc gctcgttgga gtatctaaac
    11941 cacctaaaat atataaaaga gtacttttgc cagaaccaga ttgacccatg atagaaacaa
    12001 attcaccttt cattacttgt aaagatacct cttttaacac tcgagttgtt gtatttccaa
    12061 ttttatattc tttgataata ttttttgctt ctacagctaa actattatgt gtaattttca
    12121 tattaacctc cataattatt caaacttaat ttcttctatc agtttcattt tcttcccttt
    12181 tataataggc actatcgaac ctattaaagt tactataatt cccaataacc caacaataat
    12241 aaatgtttta aaatctaaat ctggtttcat tgaaattttt ggtcctgcaa ctataaagat
    12301 agtttgaatc tcaagtatag atatcacaat accaataaca gctccaagta aacctgaagt
    12361 aaacccttca atcaatgtca cttttatatt ttgtttatta cttagtccta tagatttata
    12421 catagctata gaacgtcttt tttgaatata attaatcagt agattattaa taatacctac
    12481 tgtagcaaga agaaaaatga aataggtcat cttattcata ggagacaaaa aactacttat
    12541 agtatttaaa gaatcattat taaattcttc aactgtacga ctccaattat atgtatctcc
    12601 aaataaatat cttatctgaa tcataacagc atctggattg actgctgtat atactaaaaa
    12661 accataatta gttttatcaa aatcattaac tgcataatgt gatggtataa cagcttctac
    12721 atcatttgcg cgggatttaa aactacctac tattttataa gaaaaatcat acttatcatt
    12781 agatagagtt attgtatctc ctatagataa gcctactttt tttagagtat cttcattcaa
    12841 aataacagaa cgtttatcat taaaagcttc tattacttgt ttttttatct caaaatttgt
    12901 ataattgatt ccaaacatag agttatatag ttttatatta tctgtaccct ctagtcttga
    12961 taatgttaca ccattaccag aaatctcatt attcataaca taaagaggta atattttttt
    13021 aattccatcc atatgtctaa catcttcaat aaactcttca ttcatctttc catctgcaaa
    13081 accttgtaat tctgcgtcac gaaacacatc tgttatataa gttttgacaa agttaccaac
    13141 aacacttatt gcaataactg cagaaatact tataaatagt aaagtgatat tctgtattat
    13201 atttttgtta tttttcatat ttctagcagc taatttaccc tcattcccta aaatattttt
    13261 ataaacaaac tcaaaaacta tagacatgat atcagtaata agaggaatca acacaatagt
    13321 agctacaatt aatcccagta atgaaaatcc accagctaga tacaatgtat tttcagggga
    13381 tattcttgga agtaaaatag ataaaataaa cattatactt cctataaaaa gtatagaacg
    13441 atttgaaaca ttcttttctt ctactgttcc tagtacaata ttttttatcg gcaaatggct
    13501 agctttttta acaggtatat atgcactaaa tgaagaaacg attattgcta ctataacaga
    13561 tataatcact ccaatgggtg atattactac tggaattgat attccttgtt cgagagaatt
    13621 tcctaaccca tgaagcatta aatttaaaac aactacacca ataggaatag caattaatcc
    13681 tcctatactt ccgtataata tactttcaag catcaatata cgagttacag ttttttcatt
    13741 ggcaccaata cttctaaatg ttccaataaa aggaagacgt tctaatgtaa taaccttata
    13801 actgctgtat attataaata tactaagggt taatgcaaaa aaacttatta aaaagaaagg
    13861 cattgtcttt tgtctagcat ctgaaattat cttagtttca tttatagtat ttgataccat
    13921 atatttttca gtagaaagtt ctttggataa tttatttact agattttctg taatttcttc
    13981 ttctgactct ataagaactc ttgtatatcc actgccttta tttataattt ttgatagagt
    14041 ctctttgggt agcagtgcat ttacacctct tgtgttcctc aaaaatactg tatcataaga
    14101 tgcaatatca ctaacttgaa aagtataaga ctttccataa atctgcaaag taatagaatc
    14161 accttttttt attttatatt ttgatgtaaa gcgatttgga agaataattt tatcaccaga
    14221 aaaatcagta atactatcgc cattttctaa tcgtggcttg ttgattttat ttagttgact
    14281 taagtctgct gatataagac taaattcttc atagtatccc cctttattat aaatagcaga
    14341 gctttccaat acaccaacct ttgattttat agcatttaaa tcaggtatgt cttctaaatt
    14401 ggttaatata tctggatttt tactttggac agatatagtc gctgtaccat acataccttt
    14461 tgccattttt ctttgtgcac tttcataaga taatccaatt gagaatgaaa caaaaagtaa
    14521 aactgttgat aaaactatgg acaataacat aactgctgtt ctaatttttc gttctttaat
    14581 atttgtgaaa atatacttta atataatttt caaatttaca ccttctttcc ttatctaaga
    14641 tatttcaatc taatattttt atactttaat ctaaattaaa tctctaatag actcctccat
    14701 acttttatca ttctatttat aatattttta atcaaatcac cccttaaata aaaaagattg
    14761 ataaactact atataaatat aataatctat caaccttaat atatttttta tttgacctta
    14821 attaacctta attaaatagg aaaggtgata taaaatgagc tacctaatcc aggtatactt
    14881 tcaacagata tattccctcc atgaacttca ataatttgct tcgttattgc tagtcctaaa
    14941 ccagttcctt ctattttttg ttttgtattg cttcctctat aataacgatt aaacaaattt
    15001 gatgcttctt ctcttgacat cccttttcca ttatcagata taatgatttc aattctttca
    15061 tttaatgtta tatgtacaca aactttagta tttttatctc catatgtaaa agcattgaca
    15121 ataagattac taaaagctcg ttttaatagt gtacaatcaa aatcaaagtt aatattatct
    15181 atattactct taaattcaac tatatttgat tcatattctg gatagtttaa aatatcaatg
    15241 gataattctt tcaaaaatct tactaaatca taattatttt tatttaaagg gattattcca
    15301 ttttttaatt gataggttaa ttttaaatcg tttataagtg tatttgtata ttctatattc
    15361 tttaacatga ttgaagcata tttatatact ttttcaggtg aataattagt actactatct
    15421 gtaagaagct ctgcataccc ttttattggt gaaagtggag tttttaaatc atgagttata
    15481 tttgaaatcc actcttctct cataatatca gttttatttt gtatctcatc acttctatga
    15541 atttcttcat ttaaaatatt taaactatta tatatatcag caaaaacacc tttaatatta
    15601 actggaagat agcttcgttt tgaaatatcg ctaacagcag atgtaatatt tgatatgcac
    15661 tttgttaccc agtaaccata agcaattcca gaaaccaaaa ttattaaaaa tataatccct
    15721 atgattgaaa atacaattga cttaccacct ataaatttac ctccatcaaa aaacatattc
    15781 actttagata tatttaatgg aaaatatata atataaatat agtcattttt attattttta
    15841 attgtattaa agtatacagt tccattactt gaattatttt ggttagctaa tgctaataat
    15901 tcagaattag aataataatc tttatgctct tttggttcta aaaacccata aactctattt
    15961 ccactagaat ctaaaatttg caaccacaat tgattttctc gaagtttttc taatccagac
    16021 tgttttactt gtggcttatt atctataaat acgatttgtt cattaaagtt ttctgtaaat
    16081 tttttcggcc agtcactacg aataaattcc ccatttggtt tctgaatagt aataagtgat
    16141 aagaaaatac ctattactgt caggattaag caaataaaaa tcatgaaaaa aataatgtat
    16201 gaatgaaata ctgttttata actaggttta tgcatttaat caactctttt cttaaacttt
    16261 tattttgatt attgcttata taaaatagac aataattatt gatatgtaaa aatttattta
    16321 aaaatacaac tatctacata aattatattt atataattat atgttatcaa gctatctgtt
    16381 gtatttaata aatccttttg ataacatata aaagtaagat aaatttttcc attaaatacc
    16441 ttataattat acacaaaatc tctatatacg ttaaacagta tagagaaaat tttcatagaa
    16501 ccatctttat aggggatact ttataaaaga ataaaaaaat tataatatat aaaaacttca
    16561 taggagagta acaacatcag taaaaatatg aaaacactat ataaaaattc aaaaatatta
    16621 agaataatga aatacttgaa attgcttata tcaagaaatt ttatataata taaactggtc
    16681 aaatatgtta taatattaaa ttgtgacaag ttcatggagg tgtttatatg aaaaaacaaa
    16741 agtcgccaat tttacttgaa atgcttggac tattttttgg ttgtatatca atgagtattg
    16801 gtataaatat gtttttaaaa ccacatacaa ttgctcctgg aggacttagt ggtctatcat
    16861 tagtactaaa caaggttaca ggacttccag tatcagctat catgttaatt ataggtgtcc
    16921 cattagtaat acttgctttt agaattatgg gtacaaaaaa ttcattaaaa actttatttg
    16981 gaacagttgt attttcagct atagttcaat taacagaccc attatcaaaa ctaagattta
    17041 ctaatgactt attattgtct tctattgcag gaggaatcct agttggtata ggtttaggaa
    17101 taatgtttaa atcagatgct tctactggag gaacagactt aattgcactc atacttagta
    17161 agaaattccc aggaataaaa gctacaaaat tcatgtcatg cctagatgga atggttgtta
    17221 tatcttctgg tatagtaaat cgtagtttag aaactgctct ttactctggt atagcacttt
    17281 gtgtattaat aaaaatagca gatatgataa tggaaggatt tgaccattca aaagcatttt
    17341 ttattatctc tgatgagcct gaaagtttaa gacaagctat aactgaagaa cttgatagag
    17401 gtcttactat tcttgatggt aaaggtggat acactagaga aaataaagaa gttctattag
    17461 tcgtagtttc taaaaaacaa gaactttatc taaagagatt agttaaaaga actgacccta
    17521 ctgcatttgt tattgttaca gatgtacatg aggttcttgg agaaggattt aaaaatttag
    17581 agaactaata aaaattaata ttttaagtat atatactatt ttaattaaaa tacgatttat
    17641 tcaaaaagag tgtctcataa actttttagt tcatgagaca ctcttttttg tataaaatca
    17701 aatgcatttt cagtatttta acaataaaaa caggattatc tatattttga ggcaaccact
    17761 ttattgaaat tttatttaga aaacaatcat tactaaataa ccagcataga tattaaatga
    17821 ttatatctat tgttttttca attcatattg ataacaagga acatttttca cagtatttcc
    17881 agtatgaatt tttttgatat actttcctgt acatttaaat cctaataaat ctaatgattt
    17941 tgtagaattt tggttttctt cataggttat tgcaattatt ttatttaagt ttagttctct
    18001 aaatccatac tgtattactc tttttgttat ctcagtagca aaatcatgtc cccaatagct
    18061 tggatttata catataccta tttctgcttc taatgcttta ggatttatat tattaaaccc
    18121 catattccca ataactttat tgtctctttt atatactata gcaaagtggc caattttccc
    18181 ttttttatat ggatttagaa aaaatgattt tataaacttt cttgtatctt ctaaagattt
    18241 atgctcacta aatggtaaat gttttactac tattttattt ttataacagt caaaaaaatc
    18301 ttcaacatca tctaatgatg caggtcttag tatacaattt ctagtttcta aggttttcat
    18361 ttgaggatat tcagaatcag acatttctaa tcccccttta tacattaatc taaatatact
    18421 gttcatattt aaaatacgat attaattata taaatgttct caaattaacc ttatttttat
    18481 ttttaataaa aactaattac tatatgaatc tttcaaattt acgaatttat ctctattttt
    18541 atattaaatt acttgtgaaa tatgtattct aaattatata ttattagata tcatgcttaa
    18601 aaattctttg gttgctaagg ataaagatat atcttttaaa tggcagtaac ctatatttct
    18661 cttaggtatt ggctctttta tatctaattt aaacaatttc tcattttcca aataatctat
    18721 gctaaattct tctataacac aagacactcc aagatttata tacgcaaatt ctaaaagtaa
    18781 ttcatgagaa cccaattcta tatccgggtt tagttttata ccttttgata aaaaatattc
    18841 atttacataa agtcttgaat ttgctttatt ttctagcatt attaaaggca atgtgtttaa
    18901 ttcttccaat gatattttcc tacctttgta ttctatgtaa tcatttgcac atacaaatat
    18961 atcatgtatt tcaatacact caacaatatt tagtgtatca tcttctattg gcatgtttat
    19021 aattgctata tctatattcc catctttgag taaagatata agttctctac tcgttctatt
    19081 tattgtagat acatgtatat gtggatactt cttatgaaaa atttctaaat attttaacaa
    19141 gaaaaaacgt gcagctgtat ctcctactcc tattttcaga gaaccgtatt ctaatttttt
    19201 aaatttattt attctatctt ctcctgatga tattaacttt aatgcagtag tgacatgttc
    19261 acttagaatt ttcccctctg gagttaattt tactccctta ttgtttctat aaaataataa
    19321 agtatctaat tgttcttcta attgctttat tgactggctt acagctggct gtgacataaa
    19381 caattcctta gcagcaagag aaaaactctt attatttaca actgcattaa aaaccttata
    19441 aagttcaagt tttatattca tatataatta ctccttatgt caaatattag tattatttat
    19501 tttacttata attatatttg aattataata tacatggtac taatatgaca atattaattc
    19561 tttaggagga ttttagataa tggatagatt agttggaact gtttcaagag gggttagagc
    19621 acctattata agacaaggag atgacttagt taaaatagtt gttgattctg ttttaaatgc
    19681 gtcaaaaagt gaaaactttg aagttaggga caaagatgta attgccgtta cagaagctgt
    19741 tgtagctaga gcacagggaa attatgctca cgttgacaat attgcaaaag atgtaaaaga
    19801 taaatttgga gatgatactg ttggggttat attcccaatt ttaagtagaa atcgttttgc
    19861 tatatgttta aaaggaattg caaaaggatg tagaaaagtc gtattaatgt taagctaccc
    19921 ttctgatgaa gttggaaatc acttaataag tattgatgaa cttgatgata agggaataaa
    19981 tccttggtca gatgttttaa cagaagaaaa atacagagaa ctatttggat ataacaagca
    20041 tacatttact ggtgtagatt atgttgatta ttataagaat ttaatcaagg attgtggtgc
    20101 agaggtagaa atagtatttg caaacaatcc aaaaactatt cttaactata caacaagtat
    20161 tttaacttgt gatatacata caagacaaag aacaaagaga attttaagac aaaatggagc
    20221 taaaaaagta tattcacttg atgatataat gacagcaagt gtagatggta gtggttacaa
    20281 tgaccagtat ggacttttag gttcaaacaa agctacagaa gaaacagtaa aattattccc
    20341 tataaattgt gatgaagttg taaacaaaat ccaaggtaat ataaaagaaa taacagggaa
    20401 agatgtagaa gtaatggttt atggagatgg agcttttaaa gaccctgtag gtaaaatatg
    20461 ggaattagct gacccagtag tatctcctgc ttatacaaaa gggctagagg gaactccaaa
    20521 cgaagtaaaa ttaaaatact tagcagataa tgattttgct gacttatctg gtgatgagtt
    20581 aaaagaagca atttcaaaat acatagttga aaaagataat aaatctgatg atttaacagg
    20641 aaacatggtt tctcaaggta ctactccaag aagattaaca gaccttatag gttctttagc
    20701 agatttaaca tctggaagtg gagataaggg tactcctatt atttacatac aaggatattt
    20761 cgataactat acaaaatagt atgttttaat aagatttaat ttttttggat tatatatatt
    20821 aacatgaaaa tttattaaaa cctcttaata gatatgactt ttcaagagtt atatctatta
    20881 agaggtttat ttaatgttca cagataagat atatttaaat aatttaaaca agattgtcag
    20941 aaagttatat aatcttaaaa atttatataa ctctaattct tatttatttc tgaaataata
    21001 tcactcttca aaatttgtct tactggaata attacagcaa ctatactaat agtgatattt
    21061 aaaataatca tacctatgta tagaggtgta tttattttaa gaattggatt tatatataaa
    21121 tatacacgtt ttaccataaa ataaatcata aattgtccaa taacacttcc aattaccatt
    21181 ataatacttg catagaatcc atataaaaaa ccttctctta tcatcataag taaaaactta
    21241 ttatccgtaa tacccatagc tcttaaaatt ccaaactcat gtcttcttga aaaaattaag
    21301 tagcttactg tattgattat atggaacaaa cttattgcaa gaagtacaaa tacaatacca
    21361 tatataaata agagtttttg atttaagtag gtattatttt tttcaatagc aatggtataa
    21421 tctgttacga tacatctttt tacatcactt acaacacttt ttatgttctc agacaattcc
    21481 tcactgttac tatcttctgt cttttttata cttactgaat tataattttc gatatcaaag
    21541 ttatttttca tttgcccatt cgtcataact atatccatac cataatcacc aatgaaatat
    21601 atgttatttg ccatcacacg ttttacagta gcagcaacta caaattcttt tgttgtataa
    21661 tcattcttat tttcttcttt aaatttaaca atttcatctg ttggtttcat tgtctttggc
    21721 actttaactt ttattgtatc tcctggattt atatcaactg catcatacat cccagttcca
    21781 tccataggta gtctaactat aaccttatta tttttaacca tatcatgggt attaatctcc
    21841 ccatctataa tataagaatt taatccttct aacataccat tgttataacc ataaatattt
    21901 gtttttaaaa gatagccacc ttcattttgc tttgtacaaa taccatcaaa aaaagtcttt
    21961 atcctgtaat ctttttcaag aggtttaaag aaatttttcc aaaatagttg ttcttcttta
    22021 atttgcatag ctccaaataa atatcttact ggatagactt ttgatattcc ctcaacattg
    22081 tttaatcttg aaattttatc ttttggtata cctacatcaa aatctgttgt ttgcatagtt
    22141 atttggtagt cagaatttaa accatcatca gctttcattg taagttcatt attattttta
    22201 gtaagctgta tagagtaact agaacataga aatataattc caccaagtga taatgaaaac
    22261 aaaattccaa taaacattcc ctttttttga gtcatgtatt tatgagataa tacttttgtc
    22321 atgttagagt gttttacact ttctaatatt ctctttttct tattagtaat cttaaagttt
    22381 ttcatagatt ctatactaga gtatttattc aactgatgta caacacgtac agcaattaaa
    22441 attaacaaca ataagataaa taaaaagcct aaataaatag atttttcact tataaaaaat
    22501 gctcctggaa caatatcact actcaaaaat atatgtggaa attgttcata tattgtagac
    22561 gctactccaa tacctaagaa gcaacctata ggaaatccaa caataaaaag taaaaataac
    22621 tctaaaaata gtagaaataa aagttgttta ttattagcgc ctaatacttc taaaacccca
    22681 tattgtgata ttctctgaag tattgaaaca tggaaaatac tatatactgc tgctgcacca
    22741 aacactccaa caagcaatat aattgcattt gtatttagtt ctaaattttt taagaactca
    22801 aatatattat atttttctat attttttggt ggttttactc caaattcaac tgaaagagac
    22861 cagtttatat aagttttttc ttttgatatg ttgaattttt tcataaattt ataattttgc
    22921 tttttaatat ttttattttc atcatatttt acataaacta tataagaatc cttttcttta
    22981 ggctgaaaat aatcgtttac aaatccctcc agagcagttt ctgggtttga aagacttgat
    23041 aaaataccac ataacttata gattttacca tctaaattga tttctgttcc aatttctttg
    23101 tttacattta aattgtttag agaatatgtg tcaagtacta tctctccatc tttactagga
    23161 agagttcctt ttaataattt tctacctgtc atgtctaaat atgaagaatc agcatttaaa
    23221 aattctataa taaaaggttc atctatctga tttttaggtt ttgtaacgcc aagtctatct
    23281 acagtgtatt cctttgattt tttattttct ttaattttat taagttgttc cttatctact
    23341 ttatagaaat aatgataatc tccactatct tcccttatct tttcaattct acttttgtct
    23401 gcactatgaa ctaaagaacc aattcccgtc aataatgcta ctgatagtac tatgcttaaa
    23461 actatagata tagattgttt tttataatgc tttatatatt gaattgaaaa ttttactaga
    23521 gacatcatag taattcacca ccagtattaa ccacaactcc atcttcaata tggataattg
    23581 agtcgcatac ttgtgctata ttttcattgt gtgttaccat aagtatcgtt tgatggaatt
    23641 ttgcactact ttcttttaat aaacatacca cttccattgt agttttacta tcgagatttc
    23701 ctgttggttc atctgctaat ataagcgcag gtttatttgc caaagctcta gcaattgcta
    23761 ccctctgttg ttgaccacca gatagttcgc ttggaaattt taaacgctta tcccaaattc
    23821 ccaatgtctt catcagcatt tcaatatatt catggtctat atggtttcct ttatctaatg
    23881 taacaggaag agctatatta tcataagtgt ttaatacggg cattaaactg tagttttgaa
    23941 atataaatcc tatatttctt cttctaaaca ctgtcaaatc tttttttcct attttagata
    24001 tgttctttcc tttaattatt acatcacctg aggttggatt atctaatcca cctataatat
    24061 ttaacaatgt gctttttcca gaaccagaag ttccaactat agcagtaaat gtatctcgtt
    24121 caatttctat acttactcca tttaaggctt ttactttagt ctcacctttt ccatagtgtt
    24181 ttactaaatt attcgtcact aatatactca tttaatttct cctttcaata cagatatatg
    24241 ttctataaaa tattgtaagt gacgataatt acactcatcc tacaaaatta gtttaaactc
    24301 ttacaattct gtaagaagat actaaaacaa catccacttc ctagtttaga ttctactata
    24361 atgtttccat tttctttttc taaaattaat cttgtaagat atagaccaat ccctgtgcca
    24421 ttttggtttt caacattttt acttctgtaa aatcttttaa aaatatcatt tagttctcta
    24481 ctatcaatac ctattccctc atctttaata gtaatcttcg tatatagttc catttttatt
    24541 acagaaatag taatcgtgct atctgatggt gagtatttta ttgcattttc taaaacattt
    24601 acaattgctt ctatggtcca ctttttatta tgaactaatt ttatgtctga aaatggttcg
    24661 agatttatcc ttatattttt agcttctgct ttattaaaga tagtactgat actttgaata
    24721 agagtatctt taattagtag ttcttctact tcaaattcta taactccatc ctctaattta
    24781 gtcattttaa ataaggattg taacagccag tcaatcttaa aagtttcatt tttcatcttt
    24841 tgtaaaaact ccttcttctg taatgtggaa atatttatat tctccagaag ttcacaataa
    24901 atggttatat ttgaaagtgg agtttttaat tgatgtgaca tatttgatat taaaccttta
    24961 atcgcttctt tttctgactt tgactgttct acctctattt ctatcatatc cttaattttt
    25021 tttacttggt gagaaatttt tgacgctctt gtatcctttg tatctggata agtaacttct
    25081 ttaccttcca atatttgatt taacatcaaa tttaattcat catatctttt tcgatttatt
    25141 ttagtagata ctataaatat aacaactgta catattataa aggctaatat aaacatatta
    25201 ttctacctca ttccataaat aacccattcc ataagctgtt tttatatatt ttggattaga
    25261 tgggtcatcc tctactttta ctctaagtct tcttatattt acagatacaa tattatcatc
    25321 aacataattt tcttcgctgt cccaaatatg gtgtaaaatt tgttccttta ataatatttg
    25381 acctttattt tcaattagat aacttagaag cttatattct acagagctaa gttccaaaca
    25441 ttctttattt ttatatactt ttagtaactt ttggtccaat tttattccat tggaatatat
    25501 tactttatta ttcgattttt ttcttattgc tactttgact cttgccttta atacagataa
    25561 agaaaatggt tttgtaatat aatcatcaag ccctatttct aatcctttta cttcatcaat
    25621 ttctgagtct cttgcagtaa gcattataat tggtatatct gacttttccc ttattatttg
    25681 acatacatca aatccatctc catctggaag attgcagtct aagattataa aatctatatt
    25741 tttactatta aatatattta atccttcttg ttttgtataa gccttaaata cattaaatcc
    25801 atcattctca aatgcataaa aaagaccttc atttaagttt atatcatctt caataattaa
    25861 taagttcaat tttactctcc tttagatttt ttagataaat aattattttc ttgcattatc
    25921 atactaaaaa tattttaatt ttatttattt cactaaaaag attgtattta aatttgtttt
    25981 caaaataaaa acattataat caagcatata gttatatatt tcccaattta attacgctta
    26041 aattgaaaat ataactttat tcttatataa ttaaattata caacaataaa gttatatttt
    26101 ttaaatatat ttttactagg gggaatagaa ttgaaaaggg ttgatgagag aaatactatg
    26161 tttgcaagag caaattacaa aaaagatagt actgcttata atgactatta taagaaaaat
    26221 cctgacaaaa aagaaattga tgatagtata agaaatagac caaatttatg tagtgaagga
    26281 acaatgactt acaatgagtt aaactctcca atggcaagta gtgcattcga ttttttatct
    26341 gatatcaaat ctttatgcga aggaaaagtt tctgatacta aagtagatgt agatgcaaag
    26401 tcaatgacaa aaaaaattaa gggtcttgca aagcagtatg gagcttctgt agttggtata
    26461 actaaattaa aagactatca tatttataca aataggggta gacatgaaga aaattacggt
    26521 gaagaaatta atctaactca taagtatgca attgtatttg gatgtgagat ggataaagaa
    26581 atgataaata gagctccaat gatatgtgaa gttatagaaa catcaaagtg ctatgtggat
    26641 gcatctatcg tcggcatgat tttaagttac tatataagaa atttaggata tgatgctaga
    26701 aatcatatgg atgctaatta tttagtaatg cctgttttta tagctcgtga tgctggttta
    26761 ggagatatag gaagaaatgc tatacttaca aataaagatt atggctctag acttagatta
    26821 ggtgttgtta ctacagatat tcctctttta gaagatgaat atgttgattt tggactagaa
    26881 gatttttgta aggtctgtaa aaaatgctct tttaactgcc cttctcattc gctttctaat
    26941 gatattaaaa ttggtgatga tggaaaatat aattgggtaa ttgaacatga gacatgctat
    27001 attaaatgga gatatttagg tacagattgt ggtatgtgta tatctgcttg cccatttagc
    27061 caaaatctcg aaactataaa gaatactact tcatttaagg gtaataatga gcttattcaa
    27121 aaagctttag atgagtatac ttcaaaattt ggtaaaagaa tatttatacc tggaaatcca
    27181 tcttggttga aataatttta tttaataaag aatctgtact agaatttatc ataggacagg
    27241 ttctttatta aatatataaa tttttaaata ctttttctcg tttataacaa ttcagcaatg
    27301 tttttagtct ataattgaca ttataaaata ttaaactaaa aggagtaact gtatggaaaa
    27361 aatattagta gtagaagatg attctatatt aaataaaact ctatcatata acctaattga
    27421 agatggatat ataattactt caaaatttac agctaaatct gcactaaagt ctatttttga
    27481 atgtgaattt gatttaataa ttttggatat taatttacca gataaaagtg ggtttgaatt
    27541 atgtaatgaa ataaaggaaa attacaatat accaataatt tttttaactg ctaatgatat
    27601 ggaatgtgat atgattaaag gctatgaact tggagctttg gattatataa caaaaccatt
    27661 taatatcaat atatttaaac aaaaaattaa agctttttta aatcatctta caataaaaac
    27721 aaaacaagat tactataagg atggatatct tgaaattaac ttttctgagt tatctgccaa
    27781 tataaatgga aatcaaatta tatttacacc attagaatat cgtactttaa aactgcttac
    27841 tgaaaatcct aaaagtattt taacaaggaa agtactttta gaaaaactct gggatataga
    27901 tgctaacttt gtagatgaac atactttaac atctgttata agtaggatta gaagcaaaat
    27961 tgaaaaagac aatcttaagt atatcaaaac ggtatatggt atgggatata tgtggttagg
    28021 tgaaagaaat gaattttaaa aaattttctt ttagttctat ttatttaata attgctgttg
    28081 gtataatttt tacagctatt ttatttagta tctcaattta tctaataact ggtgatttaa
    28141 aactaattgc tctattatta atatatacaa tggtactttg tggatttata gcattaataa
    28201 tatttttact tcataaaaaa atagttatat tttgttctaa aatatgtcac actttagata
    28261 gtatgatgaa tagtgaagat aatattgaaa ttgaattaga agaagaaact attttatcac
    28321 gtatcaatca cagattaatt agaatgtatg aagttattca agaaaatcgc aatagtattg
    28381 ctatagagaa agctgattta caagaactag tttctgatat atctcatcaa attaaaactc
    28441 ctattgcaaa tttaaaaatg attaatacta ctctactaaa tcaaacattt aaaacagaaa
    28501 ttcaaaagga ttttttaatg gatatggaaa accaattaga taaattagat tttttaatgc
    28561 aatctatggt aaaaacctcc agactagaga caggtataat cacactatct aaaaagaaaa
    28621 attcaattta tgaaacaatt gctacagcac ttagtggaat tttgtttgat gctgaaaaaa
    28681 agaatattga agttacagtt gattgtgacc caaatttata tataattcat gacaagaaat
    28741 ggacttctga agctattttt aatatattag ataatgctgt aaaatacaca agttctaatg
    28801 gtaagatacg tgtagctaca gaatgttggg ttatgtatac aaaaatagat attattgata
    28861 atggaaaagg aatatcagaa agtcgccaag cagaaatctt taaaagattt tatcgtgaag
    28921 aagatgtcca tgacatagaa ggtattggaa taggtctcta tctttcaaga aaaattatat
    28981 ctcttcaagg tggctatatt aaagttacat cagatattgg aaaagggtcg actttttcta
    29041 ttttcttacc taataaataa atttttaaaa atttcatttg taatgattct gcaacatttt
    29101 ggttttatac tgtatttaca agatgttaag gaggtattat tatgagtatt ttacaagtaa
    29161 ttaatttaaa gaaatattat ggacaaagtt caaacattac aaaagctctt gatggtgtaa
    29221 ctctatctat tgaaaaaggc gaatttattt ctattgtagg tacatctggt agtggcaaat
    29281 ccacattatt aaatatgatg ggaggattag ataatcctac atctggaaag gttattataa
    29341 agggtaagga attatctact atgtctgatg aacagcttac aatctttaga cgcagaaata
    29401 taggttttat atttcaaaat tataatcttg ttcctttact taatgtatat gaaaatatta
    29461 tcttaccaat aggattggat ggagagacca tagataagga ttttataaat gaaattataa
    29521 atatgctttc tcttgaagaa aaattatatg atataccaag taatctttct ggtggtcaac
    29581 agcaacgtgt tgctatagct agagcacttg taacaaaacc agctattata ctagctgatg
    29641 aaccaacagg taaccttgat agtagaacta gttcagatgt actgagttta cttaaagtga
    29701 caagtaaaaa attcaaccaa acaattgtaa tgattacaca caataatgaa attgcacaac
    29761 taactgatag aattattcgt attgaagatg gaaaaattgt taactaggag gtgtagtata
    29821 tgtttagaaa taataatcgc acatttataa gaaaaatagc tttaaatgat ttaaaaatta
    29881 ataaacttaa aacatatctt tcaggtatca ttataatgat ttctacatgt ttattattaa
    29941 cagtgacctt agtttcatat aatgcctctg tagatttagt taatgcatct ccatatcatg
    30001 ctatatataa atctgtagat gaaaaagcaa aaaatatact atataaaaat aaaaacttta
    30061 gtggcgtagg aacttacaaa ttaattggaa gtaataaaaa gacagattgt attatgtcga
    30121 ttgtttatgc agatgataca gcaattaaac ttatgaattt tcaaccattg aaaggcaaac
    30181 tacctacaaa taaaaatgaa attgctattt cagaaaaata tttacaggaa tttggtttag
    30241 ataaagatat tggagatagc attaaattaa attattatga tgatattacg aataaagaag
    30301 ttcaatgtga ttttattatt gttggatttc tagaaaatta ttatcaagat aatgccaagc
    30361 aatactatac agtcgtttca aatgattatt ttaagaatat agcttctaca cctttacaaa
    30421 ataaaagtaa tacttttgac gagtcaagac ctgatactgt agatgtatta gttaaactat
    30481 cagaagaaaa tacagagaaa gattcagctt caattaagac acagttaaat aaaattggtt
    30541 tatctttagg tattaagaaa tataatatat acttaaatga taactatatt gaatcaaatt
    30601 taattgatgg tgagcagatt attacagttt tagtagttgg aatagttgtt cttttttcta
    30661 gcgtttttgt tatatatagt attttttata tttcagttgt taattcagtt cagatgtatg
    30721 ctaagttgaa atcgttaggt atgacttctt ttcagttaaa aaaaattatt tctctacaag
    30781 gaaatatttt gtcaattatt tttattccat taggggttat agcttcttgt ataattgctt
    30841 acataattca accattagca tggcaaatga tagctgattt atttataatt ttaattttat
    30901 cactggtaat gtttttaact gttagaattt ctttatttaa accagctaga attatttcta
    30961 aaatatctgc tattgaagcc atgcaatata cagaaactaa atttagaaaa aaagcaaaaa
    31021 attttagtta tataaatata aaaaatctag cattaaagaa tatcgagtca aatagaaaga
    31081 aaaatttgat tgcattaata tcgctaagca ttagtggagt tttatttatt tcaatcgcta
    31141 atcttgctaa ttcaatagat ttcaaaaaac aactatctca acaatttgtc tataacgaag
    31201 attatataat tagcattaag agtgataact tatatgagca tattacagaa atccaacaaa
    31261 ataatccact aacagattct cttaagaatg aaattaaatc tattcatgga gtaaaaaaat
    31321 taattgaatc caaatcaatt aaaagtaata ttatagaacc ttacatcaaa gatagagacg
    31381 aaaaacaatt tattactcta attaaaggta ttacgcctga actttcaaaa tcacttgaag
    31441 aatatattgt cagtggaaaa atagactata cacatttaga ttcagatagt ttaattataa
    31501 ataaatatag aacaaaatat tatggattaa atttaaaagt tggagataca gttacattta
    31561 atatctttag tggaaatgat attattaaaa agaaaatgaa aattatagga atcattgaca
    31621 attccaatac aggaggtatg ttttttgctt cagacaaaac tttagaatct ctaacaccat
    31681 ataatacaaa tttagatttt tctattttaa tagataaaaa gcattctaaa gaagttgaag
    31741 aaaagttgtt aagtataatt cagaaaaatt caaatttaat gctttattca tatgaagatg
    31801 attatagaat gattactaga gcatttcaat atataattat agcttcatac atttttgttg
    31861 gtttaatttc ttgctttggt atactaaata tgaccaatac cctaataaac agcgttttaa
    31921 ttagaaaaaa agagtttgca ttacttcaag ccgttggaat gacaagaaag caactgcgaa
    31981 atatgcttta tagagaaggt ctaaacataa gtatcaaagc tatatgtact tcaagtacac
    32041 taggttattt tggttcaaat ctactttgca cttttataaa agatgtaatt agattagact
    32101 ttattaattt taaattttct atatttacta ttttaatttt ttcattcgta ttaattggta
    32161 tacaagtttt agtgactgaa ttacttgtaa gaaatataga aaaaaaatca cttacagaac
    32221 gcttacgttc tcagtaagaa tgtatataaa aaatagccat tttttataca agttttaata
    32281 tgatttttta aaagctatag ggatagaaaa ttttgacttt acataatttt ctatccctat
    32341 acttgttttt attttataca gatacactta cttatatctc cgagcaacat caccagagac
    32401 ataaacaagc atattcctta ttttctaaat atgtcaattg catgacttgt aacccctact
    32461 aaatcttcac gttcacaagt agcaaggtga tattttaaat ataatgcaaa tgcatcatca
    32521 tccatagagt ctactgcttc acgcatatat aaagccaaac catctgatgc gacataatgc
    32581 agtctagtta cattaaatgc agacatcaaa tcatcaatgt tttctttacg tacaagctca
    32641 aacaaatcct ttggttcaga cttagcagca aatgtctgtg gatcaatcaa acctttttca
    32701 atatattcag atacattaat atttcctcta tggaacccct cgtcaatgag acagccatca
    32761 gatataacat atgcagcaaa aaccacacca ccaggttttg ttacacgaat tgcctcatgt
    32821 aaagcttgtt gtttatcttc tttgttataa agatgatata gtggtcctaa cagtaacgta
    32881 atatcatatt tattatctgg gaaaacagat aaatccatag cattaccctg agtaatgctt
    32941 atattttcat ttgattgagt atttttatgg aaaacctcta tattatgttc gactaattcc
    33001 actgcgtcaa catcatatcc ctgacgtgcc agtgtgtgag aataacgacc agttgcagcg
    33061 ccaatttcaa gcacacaatc acctgatttt atgtacttat caatgtaatg catagtagtg
    33121 agaaattcca ccattccatg ttttaatgca agtcgactat cttcatcata agtattataa
    33181 aagtcaatta agtattgttt tgtttccata atttcacctc ttctatatta gttaataaac
    33241 atcaaataga caaattccaa tctggttttt cttgtcttat aaaagctgtt aatatatttt
    33301 tcaacatttt ttcagcacta tatctatcta atgttaattt ttttgttgct gttaagacag
    33361 ctatgccatg agtataaaga aataaatcta aaaatattac ttttgcacat tccaactcta
    33421 ttccaatgct ttccgaaaaa agtcttgcct ttttttcatt gtcaatttct ttataaaaat
    33481 catttgcctc ttccatcatc aaatctaaat catttataaa taacaactta aataaatgag
    33541 tttcttcttg agcaaattca atgtatgaaa gcggaagcag taaataagga cttacacttt
    33601 tagaattact ataattaaca acatactgat tatagtattc atatgcaaaa gcaagaaatt
    33661 cattttttaa ttcattcatg ttttcgtaac aagtaaaaat tggtcgagtg gaacactgta
    33721 atttacttgc aatactcctc gcatttacag cttcaaatcc cacttctctt gtaatatcca
    33781 agactgtatt caaaatcatt tcttttgtta tctttacttt aggtggcata tatgttcacc
    33841 tctccattaa atttttataa aacacatatg ttatataact atagtaacat atcaagaaat
    33901 tatgtcaaga aaaagctttg catttttttg caattcctaa aacttataaa taaaacatga
    33961 gttgcaatta atctattaat agataacagc aactcagatt ttcctttaaa tactcttctt
    34021 tttgtctaat atttcatata cacaatcttc tattgaatta atatcttttt cttttctttt
    34081 tttagaatca attaaaatga aatacagtat aaaacctaca gcaagtcccc atgttccgcc
    34141 tttagcagca attacacctc ccataagtcc aatcaatccc ttctcaacac ctgtattaca
    34201 tagctccatt gatagctttg tacataaata tccttgaact aaaagtgtta ctgacaatgc
    34261 taatggtata agaggtgtag caatctgcgc aattggataa aaacagataa aaattgctga
    34321 aacccatact aatgtaccca tgccactaaa aacagactgc atggcttcct ttccaacctt
    34381 gtacctttga gcaacacttc ctgtaagtgt cgcagctaat ggaccgcaca ttggtatata
    34441 tggagaaaag attgccataa aaatatttct tatcccactt ataacattag acctatttga
    34501 attgaaatct atatattcat cttttctatt ttcactttca gaaagtacta agttttcacc
    34561 tgttataaaa tcaccaaagg caattatgta tatcataaaa gccattggta tcccttgtat
    34621 aaataacatt acacttggaa aacctattcc aaaaggagat actgtattta tcagattttt
    34681 aaaatctact atgtaaacta aattgtcaaa actaaatcta ggaatttcta tttctttact
    34741 aaatatacct actattaaac tcactaaaat agctgatact acaccatatt ctcctaaatg
    34801 aaataaaaat ttattcttaa cttttagagt atcaaatctt tcagaaaaca ttacaaaaca
    34861 agcaaccaaa attcctactg ttatagatat aggataagaa tcaaatctcc ctttaggatt
    34921 aaactctgat attatagtcg atataccgac acccattagt attccacctt taatagaatt
    34981 tggtatctta ctaactaact ttccagctac accagttata cccattaaaa taaatattat
    35041 tcctaaatct atttgtaaag ctgttaatgc ttgtattctt tcaatgccca tgctgaactt
    35101 taacaaatat gcagttgtaa gagttataga agctgtaatc cagccaggta caactgggtc
    35161 tcccataaaa acatgcaaac agtataatat tgagttaatg atagccatac tccatgccac
    35221 ttcatagggt aatcccaaaa tttgtgtact aaggccaatt gtgcctaaac ttgtcatact
    35281 tgatattata ccttgaatag cttctggttt ctcaaatctg taatgtataa atggaattct
    35341 tatcttaaac attccaaatt ttatatgagg ttgttccctt ctagcgagtc tttccataac
    35401 ttcactccac ctttcaataa ctcttataag tttacaactt tataattgtt tataaattat
    35461 caatgtcatt aaaattagta tataacatgc aaattatata aacaataaat taaatctata
    35521 aaattgatag attttgtgca tatatagaaa gaccgcttca tttttagtta cttaaatcac
    35581 ttaatattag ttatttaaat cacttgataa aggtttttta taaaattcaa tagttctatt
    35641 ccatgattca aactgtcctt ttgaatttcc ttctacagtt ccacctgaag aaaaaatccc
    35701 tctactcata ctcatacata aagtctcctt tagaggcata atatatggaa ttggtaacgg
    35761 ataacccata ttattgtatg ttaataattc tacgttatat ggataattat tttcttcaaa
    35821 gatttctaat gcctctaaac aagcttcata actattccat atgttatctt cttttccagc
    35881 aatcataagt atatctgctt tggaattttc tatttttatt ctagcctctt ttctattctc
    35941 tgctctttta agacttttct tataagtact attaaatcca aatggaatat cttttgatat
    36001 attttttttc tgttcttcaa agaatatatc attgtctact ttgatatatg gaaatggctc
    36061 tcctttatat gaccatgatg aagtatcatt tccactcatc aatccattaa gagcttggaa
    36121 acaataaatg tgaggttgtg atactacaac ctttttaatt tgttcatatc ttgaagcaag
    36181 taaaaaggcc aattctccac cctttgatgt cccatgtaca aatatttctt tagtactggt
    36241 aatttcattt tcactaatcc actcaaatac tttttcaaaa tattctaatg gaacctcttc
    36301 taatttatct ggtaaccctt ctaaagcaaa gtatgcaact gttagtacat tgaatcctct
    36361 agatgcaagt ggagctgcta aaaggtctag agcgtctaaa tttccatcag aaccacctag
    36421 cattaaaatt gttttattat tagaattttg tttataaaat aattttccta taaactcatc
    36481 agatatgtat tttgtggtaa tatcttctga tttaaatatt ctctttaatt caacttcttt
    36541 tctttcaata gaagtttcaa atatcatatt cataattatt ggtttatcaa tagatatatt
    36601 ttctgcaaaa tttttacctt cagttttaga tttttccagc gaataaatta accccataca
    36661 attatcagcc ttataagtac cttctatagg ttcaactaaa tctaaatcta cttctccttt
    36721 ttcatttgaa caaaacactc cataagatga aaattcttct cccttacacc atggaaattc
    36781 cattttcaca cttattttaa gtttagtatt tggaattaag tctgaaacca taatcttaag
    36841 tctttcatcc acaaatgatt ctacattgta tacatttact ttcataatct atttctcctt
    36901 ataataatta tttatgtttt atataaaaca gctttatcta atacaagata aataaatttt
    36961 taaattaaga caccatattg actatttcat tttatcaaca tatttcatct ttgtcaacat
    37021 attgtctttt ttagtaattt aaaattatgg tctatatgaa atccagttga tttttggcta
    37081 attaaagata ggaatgctat taggtttaga atatatatat tcaaaataaa aaaccactca
    37141 tttaaagaat ggtttttaat ataaactatt tgttattaat aaggatattt ttttatttaa
    37201 atttatataa tcgaacatct aatatttaat gtttaataaa attatgcatt tgcaaaagta
    37261 tatatggcat taactcttgc tacatataaa ttctcatcac tacatccaat atatctagca
    37321 tatttttcaa tcttttcttt tgcattttca acatcatttt catcgctctc cattaactca
    37381 tttatataaa tatccattaa tgacgcttta tattctctta tatcatagcc taaaaattca
    37441 gtcaatctct caatttcctt actaaaatct ccatcttctt ttaccaaaaa ttcgtataca
    37501 tcttccctat atggatttaa agttattatt tgttttacta ctttgcattc gtcagccttc
    37561 ccaataaaac catctttata attattaaat aaggcattag atttttttat agattcttca
    37621 tcaatataag aatgtaccgc agttatacga ttttctataa gggcatctac aacagcataa
    37681 tgaattttaa aacaatcatt gtataaataa ttgctcattt tctttattgt cgattctatt
    37741 tctaagaagc tcgcgtggcc atttttttta tttttatttg gtataataaa agttttattc
    37801 aaattattaa aaagtctctt aaaatctaaa tatttttcac aataaacact tttaaaggta
    37861 tcgatatcta tagttataat tccaaaactt actatagtct caattccttt cttaaaagac
    37921 tcttctatat atttttctcc taaacttaaa cctctatcag atatttgctt tagattttga
    37981 aaactattta aacaatctct ttcaaagttt ttagatattt ctaaagcata taatttaaag
    38041 attttcctta tcttattata attatttttt gtatcatcaa atctgataat agctccattt
    38101 acatcaaaag taatcattga gttttaacct ccccattagt ttcatcaata aaataaattt
    38161 aatataaact ttataatcat aatattaaac ttatttatac tataattatt aatttgatga
    38221 taaaagctat tttccttcta aataaaaaat ttgtctaaag tttctaaaaa atttagacaa
    38281 atcttaggtt attactcttt aaattatttt taaattattc caaatacgcc aaataatatt
    38341 ggtataaata tagctggtaa caaattggct acttttatat tcgttaattt aagtacattt
    38401 agaccaagtc ctataattaa taaacttcca gctgctgtca tttctgtgac tacaggatca
    38461 cttaaaaatc catttaaaaa tgatgctccc acacatataa taccttcata caaaaataca
    38521 gatattgcag aaaacattac acctatacct aaagaagcag taaatataat tgaagctatt
    38581 ccatctataa cagattttac aaataaagta tcatgacttc ctgtaagacc actttctaat
    38641 gaaccaacta ctgccatggc tcctatacag aataataaac tagatgatat aaaaccctct
    38701 gctatagaat cttttttatt tcctttagaa aatttacttt gtaaaaaagc acccaactta
    38761 tttacccatt tgtcaatatc tattaattct cctatcagag cacctacagc tacggatatt
    38821 attgtcacta atgtgttttt tccttctagt gctcctgata taccaatgta caatacacat
    38881 aaagcaattc cattcattat agtatcgctt actctttgag gtaatcctcc ttttattata
    38941 agacctacta tacatccacc tgcaattgct agactatttg ctattactcc aaacattttt
    39001 tctcccctcg attagctaat tgaaatttat cctattatta aaacctaaac atctatactt
    39061 tgtattggat attttaaata ttccaaaaat tcttcaaaac cttttctaga tatatttaca
    39121 gttttagtat ttatgttagg atgaaaattt aagtaatctt ctttaattac atctttatct
    39181 atgtaaagct caacttttct ttctgtatca tttattaatg aaaaaggatt tacacttcca
    39241 ggaagaagtt taagtacatt gtatagtctt tcaggtgaag caaacgataa tctagaactt
    39301 cctatcttat ctttaagtga gtttaaatca acttgttttt ctcctttaac tacaataaga
    39361 taatacttat ttcctttggc atttcttaaa aataaatttt tacattgaca cccctttgtt
    39421 attccatcta aaatgactaa ttgctctgct gtatatacag cttcatgctc tactacatca
    39481 tattcaacat ttaatttatc caaaatatca tatattttag tttcattcat gctagattca
    39541 ttttcatctt gttctttttt attatttaaa tcactcatac ttttctcctt aaacacttca
    39601 tcataatatc attgtgaggt attattctac tatagctatt gctcttactg gagctccatc
    39661 agcatcatta tacttaaatg gtgctgctat aaatagaaat ttttctggaa cattttctaa
    39721 atttgtaaga ttttctatga ttatttttcc tttttcaaat aaaatatgat gcacttcaaa
    39781 tactgatgtg tcatatctat ccactgatag catatctatt cctatgcctt ttatattagt
    39841 attagctata tagtttgcag cttcttttgt taatgtagga taacctacat agtactgctt
    39901 tttatcccaa aattttgacc aacctgattt aaatattata aaatcactat tttttatttc
    39961 atcttcatat ttttttagat attctaattc tatattctca tttccctttt caagttccaa
    40021 tacataagct tttccaacaa aattttctat atccaactta tctagggtct cacctttagt
    40081 atacatatgt cttggtgaat ccatatgagt tccattgtga gaaaatacac taattaatgt
    40141 ttcttgataa ccattttctt caataatagc tactttcttg atatctggtc tattaggctc
    40201 tgcatataca ggcatgtcat tatgtgtcac atgagttaaa tcaaaaacct tcatctttat
    40261 atacccccta tgtttttatt ttctattata tacctaaatt cattttattt ctatcagatt
    40321 ttattccatt atataccata ctactatata ttttttataa acctcaaggg atttaccgaa
    40381 aaatcttgga aagaattatc agtaaatata acatcttcac ccaaaaaacg tttatacctt
    40441 ccttcttctt tctttaaagt aattctctgt ttttgtgaat gattattaaa aaccattatc
    40501 ttaagaggag gtttttttct attagtctgc actcttttta acatgtattt tatgtgcata
    40561 tcagcttcag gaaatgaata tccacaaaat attaaaaggt cagtatctct taaagttttt
    40621 tctgtttcat tccaaacatt acttaaaaat atgtttgaca tattcttaaa atatgttggt
    40681 ggcactataa taggttctgt taactcacca cactctaaac attttgtctc tgaactattt
    40741 tcaataagct tcatgacacc accttcatgt ggtgtaagag ttacactatt acaaatgggg
    40801 caataaagcc aattcaatga cccatgtatc ttatataatt tgattaatgg ttcttttggt
    40861 tttctccaat ttaactcctc tttaaaattt gtaaactcca caccataatc aagcataatt
    40921 ggcaaatcat tcttatctct taatccagta actgtattgt ctatatgtat atcataattt
    40981 gcactaataa aagtagtatc aagaagcaaa tcattttcca aaagattttc aactaaaagt
    41041 ttatgatatt tattatctgt tctaggtgta ttatgaattg cttcagccat tagcagtatt
    41101 aaatattgtc ttaaaaaacg tatactatca cttctgttat ttagattttc tagtccaaaa
    41161 tttctaaatg cttcttttct ttgttctgct aagtctaaaa gacctaaaac ttcttcaaag
    41221 gtaggaaaat ttgcattatc tatattatct tttactatat caatattgaa catctgttta
    41281 aagaaaatat acaattctct attcattttg gtattataat ttgtgggatt tagtttttta
    41341 aaatattcgc taaaaagttc attttgaata ggtagattct ctgctgctga agctcctgct
    41401 cctaaaaata ttgctatttt catatagttc ctcctaatat aaatattact cctattttta
    41461 tatccattaa atatccatat catttatttt atgatacaac aataaagctg tcttttacta
    41521 gaaaaaatcc tattacaaga cagccttata ttatattaaa tctttaataa ttcgtaaata
    41581 gaaagagcat atatttgagt agcttttata atatcctcta ctattaagta ttcattagct
    41641 tggtgttctg tttctggttt tcctggaaaa atagctccaa atgcaacaca attatctaaa
    41701 gctcttgcgt atgttgctcc tccagatgaa agtggtgttc catcaagacc agtttcttct
    41761 tcatatactt ttctaagtgt cttaacaaga agagtatctt ctggaacata gattgaatcc
    41821 aagaaatcat attcttcata atttaaattg tatttatctg tcattttctt taactctttt
    41881 acaaaatcat cctttttgta tgttactgga atccttacat ctattcctgc aaattctttt
    41941 tcgttatcaa tagttactct acctatattt actgttagtt tacctgatac atcatccttg
    42001 caattaggaa ttatattgtt tccattagca tcttcaccaa taacttctgc taaaaactta
    42061 attatattag aatctatacc tatattatta agagctatac aaagtctagc cactgcattt
    42121 ataccagtat cacttgctgc tgaatggaca ctttttccaa ttatacagat tttattacct
    42181 tcaacagtat actcaaaatt taatttatca agttcttttt ttaatttatc agagtatttt
    42241 ccaatataga ttgctttacc tggaactgca tttaaagcct ttccaactga caactctata
    42301 tcacttttgc tatcacaagt caaatgaact tgtaaaagac ctttctctgc atttgttatt
    42361 gggaatctag aatctggagt aaatccatag tttggtattt cttcattatt ttctttatat
    42421 ttatttatac atctccaaag attttcttca tcagccccaa aaatgaatct tatcctctta
    42481 ttaaagtcta catttaaatc cataagagct ttcactgcat aaattgctga tattgtaggt
    42541 cctttatcat cttgtgttcc tcttccatac aatttaccat cttctaaaac agcttcaaat
    42601 ggagggtaat tccagctttc taaatcacct tctggaacca catcaacgtg accaagtata
    42661 cctatcattt tttcaccttg tcctatttct gcatatccat aatatccatc tttgtatact
    42721 gtcttaaatc ctaaagattt acataagtct aatatacctc ttaaagcttt atctacattt
    42781 tcaccaaatg ggcaattttc agttgcttca gatataacac taggtatttt tacactttct
    42841 tgtattgaag aaatcatttc atcttgtaga gaatttactt tttctttaat ttgctctttc
    42901 atattatcac ccttcaattt tcatcataat atactaataa atattttgac cttttaaaaa
    42961 aaaaatatgc ttattttttc agttttttta taaattcaat cgcttttaaa gtccccattt
    43021 ttgaatggtc aaatgtaagt ccaccttgaa aataaacatt ataaggaggt cttattggag
    43081 catctgcact taattctata gaagaacctt gtataaatgc tcctgctgcc attatgactt
    43141 cactttcgta tccaggcatg tcccaaggaa caggttttac ataagaatcg actggtgcag
    43201 cttcttgtat accttcacaa aaacttatta cttcatcagc attattaagt ctaatacatt
    43261 gaataatatc acttcttaag tcatcatatt ttggtaatac atcatatcct aatttttcaa
    43321 aagctcttga gcaaaagata gctcccatta cagcctgaga tactatataa ggcgccaaga
    43381 aaaaaccctg aagtacattt ctagttgttc caaaagtaag accacattct tttcctattc
    43441 caggagaagt cattctataa gatataagct caatcaaatc ttttctacca gctatatatc
    43501 cacctgtcaa tgcaagccca ccaccaggat tttttattaa agagccagcc ataacatctg
    43561 ctccaacatc agtaggctct ttggtatcta aaaactcacc ataacaatta tcaaccatta
    43621 ctatagcttc tggtttaaca gactttatta cttctatagc ttcttttata tcactaattg
    43681 aaagtgattt tctccaagaa tatccttttg acctttgtat cataacgagt ttagttctat
    43741 catttatttt gtttttaatt ccttctaaat ctaagtttcc atcctctaaa aaatctacat
    43801 catcatatgt aacaccatac tctttcaatg aacctttttc ttctcttatg cctataactc
    43861 cctctaaagt atcatatggt ctaccagtaa cagataaaat ttcatctcct ggtctaacta
    43921 taccttgtat acataaagta agtgcatgtg taccatttac aattattggt cttacaagag
    43981 catcttctgt attaaatact ttagaataaa tttcctctat tttttcacga ccaatatcat
    44041 tatatccata tcctgtagtc cagttaaagt gcatatcact tagtttagat tcttgcatag
    44101 cttttaaaac tttatattga ttatattctc ttatttcttt tatttcttca aacttatctt
    44161 ttatttcttc cattatttct tgcgatagtt taaaagtatc atcatctatt ccatagtagt
    44221 cttttaataa ttcttttgtc tcattaagca ttttatcacc tgtctcttta ttattttatt
    44281 taaacatgta aaggagacta ttttactaaa acaaataaat tatagtttat aagttagtat
    44341 aagtctcctc tcaatcatct taaattaaat taattatcta tctgttgtta ttattattgt
    44401 tgttttggtt ttgatttgtt agattaatat actttccagg ttgtatagtt gatacagcat
    44461 gtttataaat catgttttgt tgtctattat ccccttctat taatattata taactatcaa
    44521 acccctttac aagcccttta acttgcactc cattaactaa atatatagta acaggtatcc
    44581 tttctttcct tgcattattt aaaaacaaat cttgtaaatt taaaactgta tttttcatta
    44641 gatttgtacc ctcccaagat taaattgaac ttctaaaata ttcctacctt atattctata
    44701 taagttatga caaattttca atattaagtt gtatacttaa aaatttatat attattttat
    44761 agaatcttta atatataaga ttatttcatt ttttaattcg tctatatttt catattggtc
    44821 taaatcaaac cattttgctg ttttatatct tttaaaccat gttatctgac gttttgcata
    44881 ccttctagaa tctcttttaa ttatttcaat agcttcttcg tatgtatatt ctccatccag
    44941 atactttaat atctctttat aacctatacc ttgcattgat atcatatctt ttttaaatcc
    45001 catacttaaa agtttttttg cctcttcaac caatccattt ttaatcataa tatcaactct
    45061 catatttatt ctttgataca aatgttctct atctctattt agaactatta ttattggttg
    45121 atattcttca ttaaatttta aatcacttga aaaatcattc attttcttac cacttagaca
    45181 aacttcaaga gctcttatga cccttttagt attgttttta tggattctat tagcagattc
    45241 ttcatcaagt tcttttaact tattatgcat gtaatctatt cccttttcag caagctgttt
    45301 ttgaagttct tctcttaatt cattattggc atcagattgt gcaaaatcca tattatatat
    45361 taaagagttt aaataaagtc ctgtgcctcc agttactaaa acacattttt ccttttcatt
    45421 tatttcatgt atatattttt ttgctctttg ttgaaactct gaaactgaaa atggatagtc
    45481 aggcttaact tcatctataa ggtaatgctt cactccttgc atctcttcct ctgtaacttt
    45541 tgcacttcca atatccatat attcatatat ttgcatagaa tcagctgaaa ttatctctgc
    45601 attcatatct tttgctaatt ttattgacaa atctgttttt ccaacagcag ttggacctgt
    45661 aagtattata agtggtattt ttttcataac attcctttcc atatatttta aatatccaaa
    45721 tattttacat aattctttta aacatttttt ctatttctgt cttagatatt tcgaccatta
    45781 taggtcttcc atgaggacat gtaaatggat tctcacactt ttctagctgt tccaataaac
    45841 tttttatttc aatatcgtat attttatcat ttgcttttat agcagaccta catgccatag
    45901 atgcaaatct ctctcctttt aaatcataat tacttgtaat ttcttctata ttatcaatta
    45961 tttgaagtat aaatttctca gtttcaggta ctccaaatat agtaggaaca catcttacca
    46021 ttatatgatt attgccaaaa atttctagct caaaaccaaa tttcataaat aactccaagt
    46081 tattttcaat ttgaagcata tctatatttg atacttcaat aaccactggg tctaaaagta
    46141 tttgcatatt tatatcttgt ctatagaact tctccatata tctttcatat agtattcttt
    46201 catgtgcagc atgttggtcc aacaaataca tagaatcgtc tttgctcaaa attatataag
    46261 tattaaatac aactccaatt acaaaatatc cgtataaaga aaacttgcgt tttgaactac
    46321 acaagtattc ttcttcactg tccttaatac tatctcctaa gtaataattt ccttcatttt
    46381 taattccatc aacttgaaac tcttcttgta tattatcatt tgcactatct tcacttagat
    46441 aattaatgtt ttttacatca tcttctacac ttgcatttag gacttcactt actgattgaa
    46501 attcatttat tggtttttca cttgataaag taacaacttc aatgacttca tccttacctt
    46561 tagtaatatt actattttta ggagtagatt ctaataaatc attatttctt aatttataat
    46621 ctgtactttt ttctctactg ttaatagcga ttctaggttg tgttttttta tcactataag
    46681 tagcatattt tccaataaga tttgagtgta ttaatttaac ctttaaaaaa tctctaagtt
    46741 ctatatacac ttcttgttct ttttcaaatt taatttcaag tttattgggg tgtatattta
    46801 catctataca tgatgggtct acttctatat ttaagaagca cactgcatgt ttacctattg
    46861 gaattataga cttataactt tctgttattg catctatgat tattttactt tttacaaatc
    46921 ttttatttat atagatatgt tgtaagtttt tatttgaacg gtatatattg ttattaccta
    46981 tatatccatt cattttaaag tgattgcact taaactctac atctattata ttttccgtta
    47041 tttcttttcc atatatactt ctaatagtgt ttacaagttt tccatcccct ggagtattta
    47101 gcatctgttt attgttattt gtatatttaa attgaatgtt tggattacct attgcaagtt
    47161 tatttatcaa atcacttatg tttatagttt ctgcatgagt agattttaaa aatttctgtc
    47221 ttgctggtgt attaaagaaa atatctttta taatgatggt agttccatta gtagaaccta
    47281 ttggttcttt cgatattatt tttccacctt caacatatat tttagttcct attatttcat
    47341 ctttagtttt agtcgtcatt tctaattttg atacagctga aatagatgcc aatgcttctc
    47401 ctctaaaacc aagagagtat aaatcataca aatcatcaat ttttttaatt ttactagtag
    47461 catgtctcaa aaatgatttt tcaacttcac ttgaaggtat tcctattcca ttatctgtaa
    47521 tcttaattag actttttcct ccatcaatta tatctatgga aattttattt gcacctgcat
    47581 caatggagtt ttcaataagt tcttttacta cagaagaagg tctttctaca acttcacctg
    47641 ctgctatctt atttatagtc aaatcatcta ggatgttaat tatatttttc atttttacac
    47701 ctctaagatt ttatttcttt tgcttttctt tgaagattat aaagagagtt tatagcatct
    47761 aatggagtca tatttaaaat atccagattt aaaatttctt ctgatagtat atctctattt
    47821 acactatcaa aagagatttg agttaaggct acttctttta cagaatcttc ttgattaatt
    47881 ttctctttat catcattttg cttcattaaa gcaacttcat catttaatgc tttaaattta
    47941 gaatttaatt tatcataatc cttttttata tgtttgtagt cttttactat aagttcatgt
    48001 tctattttta gagattcata tttattctta aaattacttt gatttacctt aactaattct
    48061 tcgtccaaat tactattaat tatattattg ttttctttat ctccatttat tgcaacactg
    48121 ttgtaaacat gatttttttc caagtcttta agtatatatt ttgctctttc tatgacttcg
    48181 tctggtaatt tagctaattt agcaacatat attccataac tcttgtctgc tccctgagga
    48241 attatttttc ttaaaaatat tattccttcc ccatcttctt tgactgctat tgaataattt
    48301 ttaacctctt taaactcttc ttctaaatca gtaagttcat gataatgtgt tgcaaataat
    48361 gtcttacatc taatattttt ttgaatatat tccactattg accatgctaa acttatacca
    48421 tcataggtac tagttccacg acctatttca tctaatataa ctaaacttct ctctgttgca
    48481 ttttttaata taagggatac ttcgttcatc tctaccataa aagtagattg accttgagat
    48541 aaatcgtcac tagctccaac tcttgtaaat attctatcta atattggaat atcagcagac
    48601 tctgctggta caaatgagcc tatatgtgcc ataagagcta ttatagcagt ttgcctcata
    48661 tatgttgatt tacctgacat attaggacca gttattatgt taataatgtt ttctccacga
    48721 tttaaataag tatcatttgg aacgaaattt tcctctccta ctatattttc gacaacagga
    48781 tgtctaccat ttcttatatc aagtttatta ttttcattta ttgctggttt tacgtagtta
    48841 tttatatgtg caactgttgc aagggacaca aaaacatcta tattagctat agtcttagcc
    48901 actttttgta ttctatctat gtttttatat attgtatctc ttatctctac aaatatctcg
    48961 tattctaaag atttaatctt ttcctctgca tgtagtatct tttcttctat ttcctttaat
    49021 tctggagtta tatatctttc tgcattacta agtgtttgct ttcttatata tgtctcatct
    49081 agctttgcct gtttaaagtt ggcttttgtt atttctatat aatacccaaa aactttatta
    49141 aatcctattt ttaatgattt aactcctgtt ttttctcttt ccctgttttc tatttccttt
    49201 acaagaaagg ctccattctt agaaatctct cttagttcct taagttcatc actaaaatct
    49261 gatttaatta tgtttccatc ttttatggtt atcgtaggtt cttctagaat agcttcatct
    49321 attaaattgt atatatcatc taatttatcc atttctgaaa catactcttt taggattttt
    49381 gcatttgata aatttatagt atcttttaaa ttaggtaact tttctatcga attttttaag
    49441 tgaattaact cttttggtgt tactctctca aatgctatct ttccacatat tctttctata
    49501 tcgtatatat ttttaagtat atcatttagg tcttctctta atataaagtc atcttttatt
    49561 tcttctatta catctaatct attttcaatt ttagatttat ttatcaaagg ttcttctaca
    49621 tattttctta aaagtctacc tcccattgct gtagaagttt tgtcaagtac atgtaataat
    49681 gaaccttttt tcttattccc tcttatagtt tgagtaagtt ctaaattagt tctagtaaac
    49741 atatctagaa ccatatattc tgatgaattg tatatattta tattattaat gttagatgtt
    49801 atttgttttt gagtattgta tatataattc agaagaattg ataagcttga ctttattaga
    49861 cctttatcat caaactttag tttttgtaga taaacatctg gaaaatattc ttttaatata
    49921 tttatatcca aatagttatc actaaaactt tcatttatgt atatattact tacagtagct
    49981 atatctctaa gcttttctat aaagtctaaa tcatttataa ttatttcagt tggatggatt
    50041 tttgcaattt cttcaattac cttatcttca tttaaacatg ttgcattagt ttctcctgta
    50101 cttatatcaa cataagttag acctatatta gtaccatcct tatacaaaga taataaataa
    50161 ttattctttt tattttcaag taaatttcca tctaaaactg taccaggagt gatgaccctt
    50221 ataacctctc ttctaacaat tccttttgct gtagatgggt cttccatttg ttcacctatt
    50281 gctactttat atccattttc aactaatttt gatatatatg aattggctga gtggaaagga
    50341 acaccacaca taggagcacg ttcttctaaa ccacaagctt ttcctgtcaa tgctatttca
    50401 agagcttttg aagctactaa tgcatcttca aaaaacattt cataaaaatc tccaagtcta
    50461 aaaaacagta tacagtcttt atatctattt tttacttcaa gatactgttt catcatagga
    50521 gttaatttat tcatatctat ttgcattatc aaacctcctt cttttctaat taaatattat
    50581 atcatagtag atgattatta ttaacacaat atataaaatt ttgacatata actaaaaaca
    50641 atccaaaatg tatactcaca ttttggattg ctaagtttaa tgcttattaa ataaaaatat
    50701 ttttttttac aataaagata ttatttcttt tttaagttta atgatatttt caaggttatc
    50761 ttcatttaac tttctactat ctataacaaa ttctttcttt actattgatg gtttttttga
    50821 aataacataa attctgtttg atagcattat agcttcgtca atatcatgag ttataagaag
    50881 tattgttgaa tttacttttt tcttaacatc taaaagccat ttttgcatgg atgttttagt
    50941 taatgaatca agtgccccaa aaggctcatc taaaagcatt atgtcattag aatttataaa
    51001 agttctcaag aagttagctc tctgtctcat tcctccagaa agttctgaag gatatttatc
    51061 ttcatatccg cttaatccaa acacctcaaa ataaggtttt accattgacc tagctttact
    51121 ctttttttct ttttttaaaa ttagtggtag tgacacatta tctattatag ttttatatgg
    51181 caagagtaaa tctttttgat acatataact atacttacca tttatattca ctttgccact
    51241 atcataatct gtaagtttag ttataatatt aaaaatagta ctttttccac atccacttgg
    51301 ccctaatata gaaacaaact caccttcata aacatcaata cttatatctt ttaaaacttc
    51361 aatatcttta taagtttttg atacattttc tatagatact tttacttttt tattgtggta
    51421 aaaattcatt tgtgtaagca tcacttgcct tcatatcctt atctattaat ttatattctt
    51481 ttaagaatga tgtatagttg ttccatacac tatctttcat ttctccccat cgtggtgcat
    51541 catctttgta cttgcttgct aaatattctt gactctttaa agctagtttt tcatctactt
    51601 caggtgcatg ttttactaaa atttttgctg attcttctgg attttttatt gcatattcat
    51661 aaccttttgt tgtagctttt aagaattttt tagcaagctc tggattattt ttaagcacag
    51721 tttcattaga aattataagt ggtgtataat aatccaatct ctcatctaaa tcttttactg
    51781 gtataaagtt taagtcatat ccaattaaat cagctttaac tgcatcccaa ccttcaaata
    51841 tccatgcaaa atctacagtt ttcatagctg caaagaaatc atcttgacca gtattaacta
    51901 tctttaactt attaaaatca gctccatttt tcttcataac tgctttaaaa acagcttctt
    51961 ctgatggaga gccccaacca ccataagttt ttccttcaaa atctttagct gttgttatat
    52021 tcttttcttt tggtgatgca aacccagaag tattatgttg tataacagtt gctacagctt
    52081 ttattggaag tggatcttca ctagtctttg cataagtaac ttgttcttga tagcttatac
    52141 caaagtcagc ttttcctgtt gctactaaag tttctgctcc actttcaggt ggttgtacta
    52201 tttcaacatc caaaccttct tctttatagt aacccttatc aagtgctaca aataatccag
    52261 tatgatttgt atttggtgtc caatcaagca ccatagttac ttttttagaa gaagtatctt
    52321 tatcattgtt tttgtcttta ttgttatttg aagaacatcc agttattgtt gccaatgtaa
    52381 aaacacttac taaacctaat attcctaact ttttaaaatt cataattgcc tccctcaaat
    52441 acctttaatc tattaatcta tgtcttataa caactttttt tacagcctgt acaattccta
    52501 caaacattaa actaaatata actactaata tagtagatgc aaatacttta tcaagtgcat
    52561 atgcactttt tgacctaagc atataaacac caagtccttt cgttccacct agccattctg
    52621 caacagttgc tgccattaca gcatacgttg cagatatttt aagtccagaa aaaaatttat
    52681 ccattgccat aggaaattta aggtgaatga atgtattaac tttatttgag tccatagtct
    52741 taaataaatt taaataatct ttatcaatat tctcaatgcc atctacaaaa cttattaata
    52801 taggaaaaaa acaagtaagc attaccatca atacttttgg cattgttcca aatccaaacc
    52861 atatcataaa gagtggtgct ataattattg taggtatcat ctgtgtaacc aacataatag
    52921 gataaagaca tttttttatt attgatacaa aatccatcaa tattccaatt accaatgata
    52981 ttataattgc gactataaaa ccaagtattg cttctcctat agtaaccaca gcatgtatgg
    53041 ataaattttg ataatcttta aaaaacacat taattatatc tactggtgtg ggtagtatat
    53101 actgaggaac ttctaaaact cctaccatag attgccaaag aataagtata aacaaaaatg
    53161 ttgctattgg atatatacta tctttgactt tatctatgat ttctaagttt ttcatctata
    53221 gtcagacctc cagctttttc atctactcta gctactgtta tgactctttc acatccaaga
    53281 ttaaaaggga ttttatgtac cttttttaat aattcaaaaa cttcatcaaa atcaccttca
    53341 acagtagtgc tcattgctcc tatttcacat ttaagaccac ttttttcaat ttcagcaata
    53401 caagcatcta ctactttata catctcttct tcacctttgt aaggtcttag tggcattact
    53461 gctatgtctg cgattaccat ttaaatcact cctttaaaaa taattaatac ctactaggta
    53521 tattttgttt tttattaaaa aattttatta ctaaaaagat attatattta aataaaagaa
    53581 aagtcttatc caaaatagga taagacttat ttttatctta actggtctcc ctacactggc
    53641 attatccaaa caggttcaaa gggtcgagat aaaatctcct ctcagcacat tagctccccg
    53701 aaatatatta tatcttttct acttgattat actacactta tcatatttta acaaattttt
    53761 tatttatatt agatatttta tccgttcaaa aatatctaat ataaattgta cattattaca
    53821 ccaaataaat tatcttaaaa tggtaattta tcaacatctt ccaaaactag attaactgaa
    53881 ttttctagtt tttattttgc tatttcaagc atatttggat gtatatcaat tccatacaaa
    53941 tattgtgcta aatttctgtt ttcactcatc taatttgcaa tcgttacaaa ttacagatta
    54001 gaaatagctt ttagactcta cttatcttta tctacaaaaa atccttcaat aaattcatta
    54061 ataatattca gtaatctaaa aataaacctc tatctagatt tttaagatac aagcctttta
    54121 ggaagtatct tttgtgataa tataaaaatt actcatcatt atcatcaaaa tcctcagcaa
    54181 ccaacatttt agataagaat caaactctat aatataatta ttttatccaa tttatttttg
    54241 agaaataaaa tattttttta atttttaaat tttttaatat gcaccttgaa aaaagaaacg
    54301 ttttcctata ttatggtaat agtagaataa aactaaatag gcaaaactag agaaatttag
    54361 tgacgcaaag ctatagggac taagacttat gaaatgagtt atgtcagcca gttgccaaag
    54421 agatattttc tttttgtttt tatgaatgtt ttttaggggg atatatgata tatgtttatg
    54481 gataaaatgg atagatgtac acatatacta actgcatata tatgcagttc acgcgattac
    54541 tgcaatttta tagatacaca attaaatgat tttatactag aatatggaga gaatgtggta
    54601 gaatcttgtt tgcatcaagt gatggtattg gtaagcagat ataattaaag aaattttatt
    54661 ttctagaaaa ccctttttag ttttatctac gttttataat tcattaaaga actaattaaa
    54721 ataagcttca ttatatattt ttcataaagt aaacagttga gtttatctca tatactgttt
    54781 accccaatta cataattcta ataatataga ttctaatgat ttaccacgtt tagtagacaa
    54841 atattcaact tttggaggaa tagtcggata agaaatcctc ttaataagtc catctctttc
    54901 aagatacttt aattcttgtg acagtatctt atgacttata tgaacaactt ctttttttaa
    54961 ttgactgtaa cgtattggct cttgttttaa aatatgccat aaaataattg ccctccattt
    55021 acttcctatc acagtcatgg taaaaccaat tgaacaatta aaatcttttt gtctttcttc
    55081 aatatttgga aattcttcaa aattattatc tatatccatc tcaatcctct ctttcaaaat
    55141 agtaagtatc taactaaaaa gtgcattctt gtttagcgta ctaattcgta atataatctt
    55201 gattgtagta tagagcctta cataatacta cttttttaga tgtatatgtt taaactttaa
    55261 tatagacata tgttatttta ttaattttat ttaaacagat aataataaat aataatttat
    55321 ctcaagtttt ctatgtagat aaactaatct aatgtttaga aaggattata taatatgaat
    55381 aaaaaatttc gtctttatca agttgactca ttacaaaaga aaaatttaca ggtaatccag
    55441 ctggtgtaat tacaaatgct gatggcttat ctgaatcaca aatgcaaaaa atagcaagag
    55501 aattaaataa ttcagaaact gcttttattt tcaataactt ggctaaaaat catcaagaaa
    55561 attatgatgt acatatcaga ttttttacac taactaatga ggttcctata tgtggtcatg
    55621 ctactattgc tgcccattat gttagagcag tagaaaacca attcaataac aaaacagtat
    55681 ttcaaaaaac tagtgctgga atattaccag ttgatattat aaaaaaagat aatgattatg
    55741 aaataattat gacacaagga aaaattgaag tatctccacc gttacaacaa acctatcaaa
    55801 aaagattact taatgcattt ggtattttaa aggaagatat tcgtacagat tgtcctattg
    55861 ccatatcatc tacaggacat tcaaaagtta tgattggaat aaaggaatta tcaacattaa
    55921 atagtttatc tccaaattta tatgaattat cgaaaataag tcaagaaata aaatgtaatg
    55981 gatattatat ttttacatta cataataaag aaactctaca agttcatgga agaatgtttg
    56041 ctcctgcaat tggtatttca gaagaccctg ttacaggaaa tgctaatgga cccttaggtg
    56101 cgtaccttgt acattataaa gtaataccta cacccaacac agagtttata tttgaagcag
    56161 ttcaaggaga aacaataaaa cgcaaaggca agatgttagt aaaagtaatt attttagata
    56221 ataaaccagt tgaagtaaaa ataattggaa aagctgtaat tgcattctca acaaacatag
    56281 aaatctaatt atagattcct tctaagtaaa tttttgaact ttttaatact aatttaataa
    56341 caaactaatt tatatacaat caaattaatt tttttattat ttgttaatat atatttatca
    56401 ttatattata taataatata gatagttact atatcttata attagataaa tcataattat
    56461 atattattgt taaaactcaa ttatataatt tttaataata ttattttagg aggtaaaaat
    56521 gataaacgat attaaaaata aattcaaaaa ttacaaacca tatataaatg gatacaagaa
    56581 tatgaagaga gcatctgttt taattccaat agtagaaata aataacacac actatatatt
    56641 atttgaagtt cgctcaaaaa atttgaagca tcaacctagt gaaatttctt ttccaggtgg
    56701 taaaatagaa tcaggtgaga ctccatatga agctgttatt agagaaactt gtgaggaact
    56761 tggaactttt agtgacaata tagaagtaat atcaagtctt gacctcctta taacaccagt
    56821 aaagtttatc atacatccat acttaggata tataaaaaat attaataatt taaatataaa
    56881 caaggatgaa gttgaccata cttttttggt tcctataaaa tatcttttag agaatcctcc
    56941 aaatacttat agtaatactg taaaagtttt tccagacgaa aatctaccat atggttcaat
    57001 tccaaaccaa aaagattata aatttgaaag tggaagttat cctattctgt tttataaata
    57061 taaagattat gtaatttggg gaatgacagc aaaaatacta gaaaactttt taaatttttt
    57121 atcagaataa cactcataat aaatcatcaa aacttttaca taagaaattt ataaaagttt
    57181 ctaaatttaa caattctaaa atatcaataa ctatattttg tagcactttt ttattttatt
    57241 attgtttgaa tatttgatgg ttttcaatgc aatttcaaca taaatactat gtattagtgt
    57301 atactgttga tgaattaaag tatgataatc tatttaataa agtatgaagt aaatgatttt
    57361 aatgtgcctt tatggtaaaa ttactaataa gtaataaaat taattaaaat atatggaggt
    57421 gcttataatg tttgctgtag gatttgttgt tataattgca cttgcctttt tcattttaag
    57481 tgtactatta tttaatggaa aagccagtat gctactagca ggttataact ctatgagtaa
    57541 gaaagaaaaa gcacgatacg ataaaaaaaa attatgtaga agttctagca ttgttacttt
    57601 tattgtctct ataatgctat ttattatggc gtttttggga tatagaatag agagtggtca
    57661 aatggacgaa aaaaaaatgg ttcccttttc tataatattt ataatagtca tactttccag
    57721 tgtatttttt aatatcctct actctaacaa aaaatgtaaa aaataaatag ttgtaagttg
    57781 agcagttaat tataaaagat tgactgcttt ttcatgtata ttgactactc ttattaaata
    57841 ttttaacatt taaaaatcta tgtaaaaata atgaatatag tacaaacttc taataatgat
    57901 tttacctttg tggttacagt ccactatata taatttaata tgataacagg gaattactaa
    57961 tgacaactag gtaagctttt ataaaatata ataaaacaaa aatagatgta caatgaaatt
    58021 atatcttata tcaaatttat ttttattaat agcaaaaact tacattagca taacatatga
    58081 caaattcgct taaaataaaa atttttaata taatttgttc tatagtacat ctattttgat
    58141 tagtttacat aattttatta ttttgtacaa tattaattat ttactaatat cccatttaat
    58201 gaaaaagttc taggttcagt aatttttacc ataactaatt taccaattaa atcatcattt
    58261 ccaccttcga aatttacgag tttattttgt ctagttctac cagcaaactt attttcatta
    58321 tttttacttc ttccttcaac tagaacttca actattctat ctttatatcc atcatttatt
    58381 tctgcagaaa tcctatttac agcttctaac accctattaa atctatcatg ctttatatct
    58441 tctggtattt gattttccat tttagcagca ggagttccct gtcttttaga ataaataaat
    58501 gtaaaagctg aatcatatct aactttttca accacatcta aagtgtccaa taaatcttct
    58561 tctgtttctc ctgggaaacc aatcattaag tctgtagaaa aagcaatacc tggaacttcc
    58621 tttttagctt tttctattat ttctaaataa tattcctttg tataatgtct attcattttt
    58681 ttcaaaaggc tactgcttcc acattgtatt ggtagatgta aaaactcaca caccttatca
    58741 caatctctaa ttgcgtatat tacttcatca gatatatctt ttggatgaga tgtcataaat
    58801 cgaacccttt caattccttc tatatcattc acttttctta aaagttctga gaatgaaact
    58861 ggattttcaa gtgtcttacc ataagaatct acattttgtc caagtaaagt gatttctttc
    58921 gttccatttg caacaagctc ttttatctcg ttaattatat cttcaggagt tctacttctt
    58981 tctcttcctc ttgtgtatgg gactatacaa tatgtgcaga aattattgca tccatacatt
    59041 atatttacaa atgcttttaa ttcaaatttt ctattacttc taagaccttc tattacttct
    59101 ccatccacat cccatacatc cactaacatt ttgtcagaat ttattgattc tgtaagtaat
    59161 tgcggaaatt tatatagatt atgtgttcca aatataaggt ctacatgttt atattttttt
    59221 cttaattcct ctacaacatg tggttgttgc atcatacatc cacatacagc tattttcata
    59281 tctggatttt ttccttttag atgttttaat tgtcctaagt taccatacac ttttagctct
    59341 gcattttctc taactgcaca ggtgttatat attattaaat cactttcttc aaccatcatt
    59401 gacatttggt atcccatctc ttctaacatt gaacataatt tttctgaatc atgttcattc
    59461 atttgacacc cgaaggtttg agtaaacacg agttttctct ttccagttct gttgaagtat
    59521 tcttcatttt gtctgtgtat ttgttctata tatttatctt gttcttgtat tttctctata
    59581 ggtattgtta cttgttttct tttgctcacg tctattcctc ctagttaatt tcttatatta
    59641 cacataacct taattatatc aaataagaaa aatcttttaa agatattatt atttttctag
    59701 ttgtgtttta atagtaaatc taatgattta tatatactat atttctaaaa tataaaatca
    59761 tataattatt ataataataa aaagatgttt taaattaaaa cttaaaacac ctttccttaa
    59821 ataaaatata tgatttacta ttaaatacaa ttacatctat tcattttcaa ttaaataaca
    59881 atcatttaat attaaatatt gatcttcctc aaccgttata tatcttcttc ctgaaaaagt
    59941 atcattagta actattccct ctgcattacc taagctatca tttctaactt cataatatgc
    60001 atcagaagaa tttgacatta taatatattc tccagcagga atttctaatc caattttata
    60061 cataccattt ccaaacttac cattcttggc cttctgggct ttagcatact ttgctaatgt
    60121 cattgttgaa tcctcaattt taatatattg accattcttt aaggtgatat atctagtccc
    60181 actaaaaata tcatttgaaa gtatactatc agcattacct gtactatcac ttgtaacttc
    60241 ataataagaa gcataacttc ctgagtttga agttattaag tattcacctg ctgagatatc
    60301 ttttccaacc ttatacattc catcttttat agtctttgta gtaggtttaa cattttttac
    60361 aaccccagta ttaatatctc caattccatt tgttatattt aaacactgtt gtactatatt
    60421 tgaatctata tatcctatag aagttatctt cttagcattt tttaaaatgc ttttattgct
    60481 accatcgtta actaaaacca ttggaccatg ttttgataaa gaagatccta caagtgcatt
    60541 tgttaattca taagctccag ctatataaaa ctctctagca tccttataaa acttatttat
    60601 tattgcttta ttagtttcaa aacgagtact cccccctagt ctagtagatt tagtattgtt
    60661 tactaaagtg gtactcattg aagctgttcc tcctattaca taagacttta aaccactagt
    60721 tgaaaaaggt atactttgtc cattagtaag aattattggt gctttatctc ttgctgctac
    60781 agatgcaata cttatagcat ctgcttctcc tttatatgca ttggttagca taacagtatt
    60841 gacttttttt attgaattta tttcttttgc aacattataa cttgttttta ttctgtcatt
    60901 tcccttaatt cttacaactt tcattttctt agattttaat gaattttcga cagatgtact
    60961 aatagaatat gttcctccaa ttatataaac ttttgataca ttttttaatc ttgcagatgt
    61021 ctcagttggt atagtatttt tttcagttaa tagtataggg gcatttaaag ctcctgctag
    61081 tccacttgca cttaatccat ctgcaataga gttactagta ttaattaata tagcagtttt
    61141 atatgcagtt ttatatgcag ttttatatgc atttttatct gctattttac ctgctatttc
    61201 atacttattt tttccttgta ttttttctac agatgatatt gcatctacta attgaatatt
    61261 tgcaaataca aaagaaatac ttaaagtcaa tgttaatatt cttttataga atttcataat
    61321 aaaattgtcc ccctcataat aaatttttaa tatataaata catattctta aattagttat
    61381 gtacttaaca aacttat
//
LOCUS       DAGQVA010000015        58033 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.015, whole genome shotgun sequence.
ACCESSION   DAGQVA010000015 DAGQVA010000000
VERSION     DAGQVA010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58033
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.015"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            293..1324
                     /locus_tag="MIV85_001095"
     CDS             293..1324
                     /locus_tag="MIV85_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBY2960462.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            1457..2755
                     /locus_tag="MIV85_001096"
     CDS             1457..2755
                     /locus_tag="MIV85_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBY2960463.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPSNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(2869..3114)
                     /locus_tag="MIV85_001097"
     CDS             complement(2869..3114)
                     /locus_tag="MIV85_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBY2960464.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            3262..4128
                     /locus_tag="MIV85_001098"
     CDS             3262..4128
                     /locus_tag="MIV85_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBY2960465.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(4132..4668)
                     /locus_tag="MIV85_001099"
     CDS             complement(4132..4668)
                     /locus_tag="MIV85_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBY2960466.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(4859..5062)
                     /locus_tag="MIV85_001100"
     CDS             complement(4859..5062)
                     /locus_tag="MIV85_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBY2960467.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            5353..6117
                     /locus_tag="MIV85_001101"
     CDS             5353..6117
                     /locus_tag="MIV85_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBY2960468.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            6506..7819
                     /gene="prdC"
                     /locus_tag="MIV85_001102"
     CDS             6506..7819
                     /gene="prdC"
                     /locus_tag="MIV85_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBY2960469.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      8223..8308
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            8890..11139
                     /locus_tag="MIV85_001103"
     CDS             8890..11139
                     /locus_tag="MIV85_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBY2960470.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTSDVEKPSDGQVPDGEKPSDSQVPDVEKPSDGQVPDGEKPSDSQVPDGEKPS
                     DGQVPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQ
                     TPDVEKPSDGQMPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINK
                     IVYNFWEDEEDVKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYH
                     DLRFDDITKTLTFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSP
                     YLPAEDFNGQENQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWI
                     ILGQMDEQERLKQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAG
                     REELKPNNTGKPSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLKLPDGVTAYDG
                     DGNIIGTGEVEISTQQKFKLKSVGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKD
                     HSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPT
                     DDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPVPPMEDAVLNPP
                     VPPTEDTVLNPPVPSVSDTVEKTPELSRDDTIIKSPKTGDETQLMSYVFISVIAICGL
                     AYQCKIKRN"
     gene            11546..13306
                     /gene="prdR"
                     /locus_tag="MIV85_001104"
     CDS             11546..13306
                     /gene="prdR"
                     /locus_tag="MIV85_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBY2960471.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            13735..15615
                     /gene="prdA"
                     /locus_tag="MIV85_001105"
     CDS             13735..15615
                     /gene="prdA"
                     /locus_tag="MIV85_001105"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBY2960472.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            15696..15980
                     /locus_tag="MIV85_001106"
     CDS             15696..15980
                     /locus_tag="MIV85_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960473.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            16018..16743
                     /gene="prdB"
                     /locus_tag="MIV85_001107"
     CDS             16018..16743
                     /gene="prdB"
                     /locus_tag="MIV85_001107"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:16468..16470,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBY2960474.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            16823..17581
                     /gene="prdD"
                     /locus_tag="MIV85_001108"
     CDS             16823..17581
                     /gene="prdD"
                     /locus_tag="MIV85_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBY2960475.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            17596..18063
                     /locus_tag="MIV85_001109"
     CDS             17596..18063
                     /locus_tag="MIV85_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBY2960476.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            18081..18563
                     /locus_tag="MIV85_001110"
                     /pseudo
     CDS             18081..18563
                     /locus_tag="MIV85_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
     gene            18583..19590
                     /locus_tag="MIV85_001111"
     CDS             18583..19590
                     /locus_tag="MIV85_001111"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBY2960477.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            19710..20591
                     /locus_tag="MIV85_001112"
     CDS             19710..20591
                     /locus_tag="MIV85_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBY2960478.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            21259..21894
                     /locus_tag="MIV85_001113"
     CDS             21259..21894
                     /locus_tag="MIV85_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBY2960479.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            22078..22647
                     /locus_tag="MIV85_001114"
     CDS             22078..22647
                     /locus_tag="MIV85_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBY2960480.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            22725..22862
                     /locus_tag="MIV85_001115"
     CDS             22725..22862
                     /locus_tag="MIV85_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960481.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            22859..24634
                     /locus_tag="MIV85_001116"
     CDS             22859..24634
                     /locus_tag="MIV85_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2960482.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            25059..26366
                     /locus_tag="MIV85_001117"
     CDS             25059..26366
                     /locus_tag="MIV85_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBY2960483.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            26694..27233
                     /gene="hpt"
                     /locus_tag="MIV85_001118"
     CDS             26694..27233
                     /gene="hpt"
                     /locus_tag="MIV85_001118"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBY2960484.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            27611..29287
                     /gene="bclA2"
                     /locus_tag="MIV85_001119"
     CDS             27611..29287
                     /gene="bclA2"
                     /locus_tag="MIV85_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBY2960485.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGVTGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGENGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVTQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(29870..30625)
                     /locus_tag="MIV85_001120"
     CDS             complement(29870..30625)
                     /locus_tag="MIV85_001120"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBY2960486.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHDTLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            31065..32054
                     /locus_tag="MIV85_001121"
     CDS             31065..32054
                     /locus_tag="MIV85_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBY2960487.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(32506..33222)
                     /gene="dapD"
                     /locus_tag="MIV85_001122"
     CDS             complement(32506..33222)
                     /gene="dapD"
                     /locus_tag="MIV85_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBY2960488.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(33446..34195)
                     /locus_tag="MIV85_001123"
     CDS             complement(33446..34195)
                     /locus_tag="MIV85_001123"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBY2960489.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(34262..35149)
                     /locus_tag="MIV85_001124"
     CDS             complement(34262..35149)
                     /locus_tag="MIV85_001124"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBY2960490.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(35266..36267)
                     /locus_tag="MIV85_001125"
     CDS             complement(35266..36267)
                     /locus_tag="MIV85_001125"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBY2960491.1"
                     /translation="MKKVNVAIIGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(36692..37573)
                     /locus_tag="MIV85_001126"
     CDS             complement(36692..37573)
                     /locus_tag="MIV85_001126"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBY2960492.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGIISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            37896..39089
                     /locus_tag="MIV85_001127"
     CDS             37896..39089
                     /locus_tag="MIV85_001127"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBY2960493.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            39295..40413
                     /locus_tag="MIV85_001128"
     CDS             39295..40413
                     /locus_tag="MIV85_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBY2960494.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            40544..40789
                     /locus_tag="MIV85_001129"
     CDS             40544..40789
                     /locus_tag="MIV85_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBY2960495.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            40776..41522
                     /locus_tag="MIV85_001130"
     CDS             40776..41522
                     /locus_tag="MIV85_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBY2960496.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKSEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            41807..42682
                     /gene="hslO"
                     /locus_tag="MIV85_001131"
     CDS             41807..42682
                     /gene="hslO"
                     /locus_tag="MIV85_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBY2960497.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            43073..43873
                     /locus_tag="MIV85_001132"
     CDS             43073..43873
                     /locus_tag="MIV85_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBY2960498.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            44400..46640
                     /locus_tag="MIV85_001133"
     CDS             44400..46640
                     /locus_tag="MIV85_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBY2960499.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            47054..48589
                     /locus_tag="MIV85_001134"
     CDS             47054..48589
                     /locus_tag="MIV85_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBY2960500.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            48605..49366
                     /locus_tag="MIV85_001135"
     CDS             48605..49366
                     /locus_tag="MIV85_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960501.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            49704..50573
                     /locus_tag="MIV85_001136"
     CDS             49704..50573
                     /locus_tag="MIV85_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2960502.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEVARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            50902..51153
                     /locus_tag="MIV85_001137"
     CDS             50902..51153
                     /locus_tag="MIV85_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBY2960503.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            51265..52044
                     /locus_tag="MIV85_001138"
     CDS             51265..52044
                     /locus_tag="MIV85_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBY2960504.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(52179..52829)
                     /locus_tag="MIV85_001139"
     CDS             complement(52179..52829)
                     /locus_tag="MIV85_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960505.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(52826..53329)
                     /locus_tag="MIV85_001140"
     CDS             complement(52826..53329)
                     /locus_tag="MIV85_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2960506.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(53378..53893)
                     /locus_tag="MIV85_001141"
     CDS             complement(53378..53893)
                     /locus_tag="MIV85_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBY2960507.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            54173..54697
                     /locus_tag="MIV85_001142"
     CDS             54173..54697
                     /locus_tag="MIV85_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2960508.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNTNYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            54681..56084
                     /locus_tag="MIV85_001143"
     CDS             54681..56084
                     /locus_tag="MIV85_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2960509.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQLFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(56648..56959)
                     /locus_tag="MIV85_001144"
     CDS             complement(56648..56959)
                     /locus_tag="MIV85_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960510.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(57015..57608)
                     /locus_tag="MIV85_001145"
     CDS             complement(57015..57608)
                     /locus_tag="MIV85_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2960511.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT        22437 a         6868 c        10196 g        18532 t
ORIGIN      
        1 aaaattgatg cttaatcata gataaatatt aataaaatat acaaggggat tgtctaataa
       61 aaagataatc tcctttttta caaataattc taaattgtga tataaatcta aaaattttat
      121 cttaacattt aaccatttaa tgataataat tgatataata aatataaatt aaatatatgg
      181 tgtacttatt ttatgttttt agcaagaaat atagcattta aaagataaat tgtgcaactt
      241 aaatcaaagt ttaagatgaa ctattaacat agatatatta aaaacttttg taatggagaa
      301 tatatgtgat atgaataata aagttaaggt tgcagtatta gatacaggaa tagacaaaga
      361 acatgattac ttaaaagata atttagttgg aggaattgct tttgaatgta tgcatgatta
      421 tatctttata tcagataaat ttgatgatga agatggtcat ggaactgctt gtgcatcaat
      481 aataaagaaa gagtatgaag atgtagagtt atttgtaata aaaattttga gaaaagatgg
      541 tattacaaat ataaaagttc ttgaagaagc attaagatac cttttagaca ctaacataag
      601 attaattaat ttaagtttat cagtcatagg agtagaaagt gttaagggct tatttgaagt
      661 ttgttatgaa ttgtttagaa aaggaaaaat aatagtatgt tcactcgcta atgattttga
      721 cttaagttat ccagctatgt ttaacaatgt tataggtgta agaggattta ctttagatgg
      781 agatgattca ttttggtaca acaaaaaata tgatgttcaa tgtgttatgg atagcaattc
      841 atatataagt tgtgatataa ataattccta tagattacca ccaaaatgta atagttattt
      901 atcagcaaag cttactggta aaatagctaa gatattatca gaaaaaccag gcataacaat
      961 atctgattta aatgataagc ttgaatcatt agcaactaga aatcattggg atagttgtga
     1021 ttttgatgag tgtagtagaa ttgtaaactt taaattggat ttgtatgaca aagaaaatgc
     1081 tctttttatg aaagttgctg acgttgttag ggattgctta gatattgaag agaataatga
     1141 aaaactcttt aagggtagcc tttttaataa ggagataggc ttggtttatg ataattgttt
     1201 taatctgttg aaaaagctag agcatagatt tgacataaag tttaattata tggacatctc
     1261 aaaatatgac ttagtttcaa tatatacact gactgaatta gtggaaagat ataaaaactt
     1321 ataaataaag atttgtagct aaatttaatg tagaaggtat taaattatat gtattctttg
     1381 tcggtagatt aaaagtaaaa aatatactat aattagatag cataagagaa aatgccaata
     1441 cagggggagt tagataatga aatatgaaga agcattagag tacatatcac aaactaataa
     1501 attcggtata agattaggat tagaaaatat cggaaagtta ttagaattat taggaaatcc
     1561 acaagaaact ttgaatataa tacatgtagc tggaactaat ggaaaaggtt ctgtgtgttc
     1621 ttttgtttct aatatactaa gagagtgtgg atataaagtt ggtttatata catctccata
     1681 tttagaaact tttactgagc gtataagagt aaatggacaa aatataccac aggatgatgt
     1741 tgctagaata attgagttaa taaaagaaaa aatagagatt atggtaaaag aaggctatgc
     1801 atatccaaca gaatttgaag tggttactgc aatggcattt tattactatt cagaacaaaa
     1861 ggtagacttt gtggcattag aagttggttt aggtggcaga tatgatgcta caaatataat
     1921 aacaaaatca cttgtaagtg tgatagtatc tataagtttg gaccatacag gtatacttgg
     1981 agatacaata gaaaaaatag cgtacgaaaa ggctggaata ataaaggaaa atggagtagt
     2041 actagtatat gaccagactg atgaagcaaa ggatgttata aagtcagttt gtaaagagaa
     2101 aaaagctaaa tatatagaag ttgattttga tgatataaac ataaaaaaat cagatataaa
     2161 ttctcaaata tacgattgta ctgtaatgaa agaaacttat agagaccttg aaataaaatt
     2221 gataggcgaa catcaaataa acaattctat cttggcaatt agtgtaataa aatatctaaa
     2281 agacataaat aaattagcaa atataaatga agaatctata agaaaaggac ttataaatac
     2341 taaatggcca ggaagaatag aaaagataaa agaaaatcca atttttataa tagatggtgc
     2401 acataatgaa gatggagcaa aatctttggc aaaagcactt gataagaatt ttaaaggtag
     2461 aaaattaacc ttattaatag gtatgttaga agataaagat attgatagtg ttttagagat
     2521 attgttgcca cattttaata aggtaataac aacaacacca agtaacccaa gagccataaa
     2581 ttcagatata ttaagagaaa aagtattaaa atatgtagat gatgtaacat caaagcatga
     2641 gatagaggat gcagtaaatt atacattaga aacatcaagt gaggatgata ttataataag
     2701 tgcaggttca ttatatatga ttggtacagt gagaacttta gtaaagaaat tataatttta
     2761 taaaataagt atacaaataa aaatataaaa aagagttgtc taaaaaatgg acaactcttt
     2821 ttatataaaa taagttttta ataattttac tgatgtttat ataagtaatt atatagattg
     2881 acgtatagct ttagataatt ggtctgggca agaagtacct tttccaccac agtcaatacc
     2941 atttaattta tcagcaactt caagagcatt ttggccaatt attaagcttc taagtcctga
     3001 taaattacca ttacatcctc ctataaattc agcatcaaca atcacattat tttcatcaac
     3061 ttcaaaaatc atttctctac aacatacacc acttggatta aatgttactt tcattaaaaa
     3121 gacctccatt aaatattatt tcttttttta acattaataa taataccaaa tatatgcgta
     3181 ataatgcaac tataaagcat aatacaagct aatgaaataa tatattattg tagtatatgt
     3241 attgtagaga ggaggggtta tatgaaaatc tatatttcta actacttatc aaagagtatt
     3301 agcatagttg attattctac acttgaacta gaaaaagaaa tagtattaga agataatata
     3361 tatccacacc atttttgcat agaaaaagaa aaaaatttaa tatacatacc tagttcaagt
     3421 aatgggatac tctatgtctt agatttaagt aatgataaaa taattgatac tgtctctata
     3481 ggaggaagtc ttagtcaagt tgtacttagc gataatgaat tgtttgtggc aaatgaagat
     3541 tctaatagta tatatgtact agataaaaac acattaaatc caataggaat tattggagtt
     3601 gataatatgc cacatggatt tgactttgat agagaaagca aaaagttata tgtaccgtgt
     3661 ataaactcga tagtatgtat agatacaatt aataaaaata tacaaaagaa aataaatatg
     3721 gactttagag cttggcatat agaacttgat aaacaaaaga aagaaatgta tatatcaaca
     3781 cttgatggaa agcttataat aatagatgaa gtaagcatgg atataaaaaa ggtattatat
     3841 gaatttttat taccagtaga aataagattt aattatagtg gcaaaaaagt ttatgttgct
     3901 gatttgggtt ataataatgt aagaatttta gattatacaa cgagtagata cattggaaat
     3961 attgaaataa atgggattcc ccaaggatta gaaatatcta aagatgaaaa gttactattt
     4021 gtatcagata cacaagaaaa ttcagtaaaa gtttatgaaa ctgcaaataa caaattaata
     4081 aaagaaatca aggtaggaaa agagcctaca actataattt gtttgtaggc tttaatgtat
     4141 gtctcttata agtaaatcga taacttcggc atacatataa gatgcattat ttttccagtt
     4201 attgcaaata agttttgctt gtttctctga tgaaacattt agatttaaat ctattaagtt
     4261 agactgattt tctatgactc taaggttgac aataaattca ttatcacttt gttttacaaa
     4321 actagacttt acttgagtat ctgctagtag attttctttg ttagaatcta tatacttgtc
     4381 tattttttca gtaacactag taggtattcg attaaagaag tattctagac tttctacgcc
     4441 tctttgagta agagcataat attctctgtc agagtcttta tatgtagtca aaaacttaga
     4501 ttccataagc tgagataaaa gctgttgtaa tgaaaaataa ttcatcatct cagtctctaa
     4561 tactacttga gttatttgag aattagttaa atccatttta attttttcta atatatataa
     4621 aattaaaagt ttgtgatagg ctaattcttc agacgagttt tcaaacataa atatcatcct
     4681 ccgtcaaact atttctatat ataatatatt aaactaattt gtacaaaatt aaaagaacaa
     4741 tttgtattgt attattaatc tttaataatt catataaaaa caattttata aataaatata
     4801 gaaaaacagg gctgctaatt agcagccctg ttgataccca ggtgtcaaaa tttactattt
     4861 attttccagc catttgtctt tcagccattt caactaattt cttagtcata tatccaccaa
     4921 catatccatt ttctctagct gttaagttac ctttgtctat gttttcatag ttagataaac
     4981 ctatttcgtt agctatttct aatttcattt ggtttaaagc agcttttgct tctggaacta
     5041 ctgttctgtt tgaatttgac atagtaaatt tcctcctcaa ataattagtt tatgatgtct
     5101 aacaacactt ttatttatgt gatgttaata ctaatttctc caaaataaaa ataatatata
     5161 cagaaaaata aaggtaaaaa tgtaaaaaat ataaaaaaat taaataaatg agtattttag
     5221 agagtttaat taggtcaata taggttttat ttttttagtt attgtcttat aaattaaata
     5281 ttacagtact tttttgagct gaaaaaaaat aaattttaaa tatagaagaa attatttcaa
     5341 agggggaata gtatgaaaag agaagttaaa aggactaaag ctttgatata tagtgtttta
     5401 tttttttcat tattattagt gttaatattt gtttttgttt atggaataaa atacatatgt
     5461 tctaaatctg acaattcaaa aatgcctata tataaagttg atacaaatga gaaaaaaata
     5521 gctttgagtt ttgatgtagc atggggaact gataatatgg atgatatttt aaaaatttta
     5581 gataaacata atgtaaaagc gaccttcttt ttagttggta gttgggtgga tgataatgaa
     5641 gaaattgtaa aagctataga tgaaaaagga catgaaattg gaaatcattc aaatactcat
     5701 gccaatttaa aggaaatatc aaaagaagac ataacaaaag agatagaaac tacatcagaa
     5761 aaaatatata atataacagg aaaaaggact aatttattta gacctccttt tggggacgta
     5821 aacaataaag ctatggacat ttgtagtgat ttaggttata aagtaattaa gtgggatgta
     5881 gattctatag actggaagga gcttggacca aatcatgtaa ttgaaaaagt aataaaagaa
     5941 tctcaacctg gttcaatagt tttattccat gctaatataa atgatgtaga taattatttg
     6001 gatactataa taagtcgact aaaaaaagat ggatacagtc tagtcaaaat atctgatttg
     6061 ttgtataaag ataattatgt agttgattcc aatggagtgc aaaaaactaa gaattaataa
     6121 gtaataaatg tatattttaa gtaaagttgt gataaattat atagtatatg ttagaaaagt
     6181 gtcgataaaa agacggtgtc tattttttga cactttttat acatgtatgc aatatcaata
     6241 attatagatt aaattgatta aaaaagtgtc taataattga cttttttttg atgggtttaa
     6301 aaatttagaa gaattaatga atgctgtaag acagtatttc caaagggtat aagtttgttt
     6361 aaaagttggc atagaaattg ctttgttaat aagcgatatg ttctatagaa ataaacaata
     6421 tgttaagacc ttataataga aaaatagcat taacattatt tgaacagctt ataaaaaaat
     6481 taatatactt aagggggcgt actagttgaa caaactatat tctattttat taaaacaaca
     6541 cgttggtggt ccagataagc cagtagtaag tgttggagat gtagtaaaaa aaggaactct
     6601 aatcgcagaa ccaactggat taggggcaaa tatttatgcc agtgttagtg gaaaaataag
     6661 tgaaataaat gaccaagcga tagtaattga agctgatgaa gtacaagaag atacttttga
     6721 accattaaaa ggagaaggta tacttgactt aattaaagaa gctggagtag taggaatggg
     6781 tggagcagga ttccctactc atgtaaaatt aaacatagat ttaaatggtg gaacaatatt
     6841 agcaaatgca gctgaatgtg aacctttatt agctcataat ataaaagaaa tagaagaaag
     6901 accagaaata gtttatcaag gtataaaata tgctatggaa gttactaatg ctggaaaagg
     6961 tatgctagca ataaaaagta agcatccaaa agcaatagaa gctttcaaaa aagtaataaa
     7021 gccaggagac aacatagaag ttgcagaact agttgatatg tacccaatgg gagaagagag
     7081 agcaatagta agagatgttc taggaaaatt acttgagcca actcaattac cttcagaggc
     7141 taatgcagta gtaataaacg tagaaacact aactagaata gtagaggctg ttgagcaaaa
     7201 aagaccagtt atatctaaaa atataactgt agttggtcaa ttaaacagtg gaaaagaatc
     7261 tatagtgttt gaagatgtgc caattggaac aactgtcgga gaattaattg aaagagctgg
     7321 tggaataaaa ggtgaatatg gtgaaataat cctaggagga cctttcactg gtaaagctac
     7381 tactttagat gctccaataa ctaaaactag tggtggtata atagttacta tgccatttgt
     7441 taatgaaaag agaaaaatgg gtcttttagt ttgtgcatgt ggacctaatg aagaaagaat
     7501 gagagatata gcaactaaaa tgggagttac tgatatagta tcagttcaaa aatgtaaaca
     7561 agctcaagaa attaaaggtg cattaaaatg tgaaaatcca ggacactgtc caggacaagc
     7621 tcaaaaatgt attgaattta agaaagctgg agcagaagtt atattaatag gaaactgtac
     7681 tgactgtagt aacacagtaa tgggttctgc accaaaatta aaattaggtg tatatcatat
     7741 tactgaccat gtaatgagaa cagttaatca cccattaata agaagaataa aaggtgacgt
     7801 aagattaaaa ataaaataat agataaatag aagttagaca tctttagaag taaaacttaa
     7861 aagttacttc taaggatgtt ttttaatgta ttttgagggc aatatatata ttgtaaaata
     7921 aatggaaaaa atagacaaaa tatgctagat attgtataat gataacaata gctattacaa
     7981 ttaatattgg acaaaaataa tgatactcaa gtatgtggtt tgtattaata tgcatattat
     8041 attaagtcaa ctatccgata gagtaaaagg tttttgtgat atttgaagat actctatagt
     8101 atctttttta ttataaaaac taatttttgt cttttattag ataagtatct aggatactaa
     8161 tttatatttt attgagttgt taaaaaagtg cacttaaaaa gttaaaaaag aaaaattaaa
     8221 aacctattta tagaaactgt gaagtatatc ttaaacctgg gcacttaaaa gatatatgga
     8281 gttagtagtg caacctgcta taaatataaa taggagtaac ttttaattgt caaaaatata
     8341 taaaataaat acataaataa gtaattaata gaagatagat ataaatatat ttttgaaatg
     8401 ctccctgcat tcataacgag tgtagagtgg cagatatctg cccaaaactc ctttaattgc
     8461 tggaagttcc taaagctaac taaaccacaa cataatcatg aaataaggat aagtgtgata
     8521 gagtgtgcat ttaataagca cttgaggtta cgaaagtaga aaaaattagt tagatagcat
     8581 aaggttaaat cctaagtgcc ttgaaaatgg ataatcagca ggtaagcttc gaaaagaaga
     8641 aacttcaacg actagagaga aatctcgtac ctacaagtgt ggggaaatgg ggagtaccta
     8701 atttatggtt aggtaatgat atagtctgtg cttaatagaa atattaagaa gttcatagga
     8761 gaactggtta ggagtaacga ccctaattga acacactaaa gatgtattat tgaataagat
     8821 tcatataata tttaataatt ttaattatat taagtgaata caatatatgt ttttagtatc
     8881 aggagaattt tgaaaacaaa aattaaaaaa tcaagtataa tcagtttagt aattgctttt
     8941 agtatggtat ttactgcatt tacaccaata gtatcttatg ctgacgaagt gactagcaat
     9001 gatacaatac ttaatggaga agaacaatca aatggtcaga catcagatgt agagaaacca
     9061 tcagacggtc aggtaccaga tggggagaaa ccatcagaca gtcaagtacc agatgtagag
     9121 aaaccatcag acggtcaggt accagatggg gagaaaccat cagacagtca agtaccagat
     9181 ggggagaaac catcagacgg tcaggtacca gatggggaga aaccatcaga tggtcagata
     9241 ccagatgggg agaaaccatc agatggtcag ataccagatg gagagaaacc atcagatggt
     9301 cagataccag atggggagaa accatcagat ggtcagatgc cagatggaga gaagacatca
     9361 gatagtcaga cgccagatgt agagaaacca tcagatggtc agatgccaga tggggagaaa
     9421 ccattagatg agcaaactcc agaagaagaa aaaccattgg aagaagaaat agttatagag
     9481 gaaatgagtt taaaacaaga tattgataaa attcttgata tgactttatc tcaaataaat
     9541 aaaatagtat ataacttttg ggaagatgaa gaagatgtaa aggcagatga acaatcagaa
     9601 attaaccaag tttttacttc agaagactca tttattagct tatggtatga caaaaaagca
     9661 aaagtaaaaa attcttgttt actaaaagaa atagatggtt cagatagacc ttatcatgat
     9721 ttaagatttg atgatattac aaagacttta acttttgact atgtaataaa gggtcttgta
     9781 ggagcaagct caaaagacga caaatatgta atagaaggtg aagatggaga gcaaactgca
     9841 ttttgttaca ataatcattt aagaccacca agtagtaatg gaaagagtcc atatttacca
     9901 gcagaagatt ttaatggtca agaaaaccaa aatgaagaag cagttaaatc tatactatat
     9961 gcaggttctg aatttgatgg atttggatat aagcaacaat ttaatttagg tggagaagaa
    10021 aatgaattga tgacttactc agctactcaa agtgcaattt ggattattct tggacaaatg
    10081 gatgaacaag aaagacttaa gcagtatcaa ggttctataa acctttgtga taaacttata
    10141 gaaagagcaa aaactgaaga ggaaagagct gagtatcaga agaagaaaga agtagcgata
    10201 aatataaaag cttatttaga agcattgtta aaagcaggtc gtgaagagtt aaagccaaat
    10261 aatacaggaa aacctagttt gagtaatggt ttaactaaga ttaactttga aaaaaatgaa
    10321 gatggtactt atgaaacaga agctgtagcc ttagtaggtt atagtggtgt agtaaagtta
    10381 aaactaccag atggagtaac tgcttatgat ggagatggta atataatagg tacaggcgaa
    10441 gtagaaattt caacgcaaca gaaatttaaa cttaagagtg ttggaaaacc agatgccaaa
    10501 gctaatattt ctgctgtatc ttatgattat atttttccaa aagctattca atattataag
    10561 gcagtgcttg atttaggaca aaaagaccat tcatcttcat taccatctag caagcaaaat
    10621 ttattaagtt atacaataga gaaaaagaat ggtcaagaag ttaactttaa tataggttta
    10681 ccaacagatg atgatgatgt tgtaaatcca ccagtgccac caatagatga tgatgttgta
    10741 aatccaccgg tgccaccaac agatgataca aatggacata agccaaaacc atcaccacca
    10801 atagatgata cagtaataaa tccaccagta ccaccaatgg atgatacaat aataaatcca
    10861 ccagtaccac caacggagga tgcagtgtta aatccaccag tgccaccaat ggaggatgca
    10921 gtgctaaatc caccagtgcc accaacagag gatacagtgt taaatccacc agtaccatca
    10981 gtaagtgata cagtggaaaa aactccagaa ctatcaagag atgatacaat aataaaatca
    11041 ccaaaaacag gtgatgaaac tcagctaatg tcatatgtat ttattagtgt cattgcaatt
    11101 tgtggattag cgtatcaatg taaaataaaa agaaattaat ctagattatt attaagttta
    11161 aaataaaaag tctcaaattg atttataagt cattttgggg cttttttatg taaatataat
    11221 atgcaaatat agtttgttta aaaatatcta ttttaattat attcttaaat ttattattgg
    11281 atacaggcat tcattaattg tttgatgaat agaaaaatgt tttgaaggtg aaaatagtat
    11341 tgaaaaaata atatactaag ggtataattc atttgatttc atttgtataa atttaattat
    11401 aaattttaaa gtgattatat aaatttaaat gctaattact taataaattt taataataat
    11461 tatttaataa ataattatta taatatgcta gaataaatat atataaataa gttttgatga
    11521 ggtactacta taaagggggg actttatgtt ttcgatacca gaagtaaaaa aagtagaaga
    11581 ggtaatggat acaaaattta caactataga cgaagacaca agaattgaag atgcaataaa
    11641 agaaatgata aaaagcaaca caaaaactct aatggtaata gattcatctg accaattaaa
    11701 aggcattata tccatgacgg atatacataa tctttatgag atgcataaaa agtatgaagg
    11761 tcaaccagta aaacttataa tgaagaagga tgtaatatat gtcaacgaag gtttaacctt
    11821 agatgaatgt agagatataa tgatattaaa aaatataggg attcttcctg ttcttagaga
    11881 taataaaatt attggagttc taaaacaaga gcacattagg gactatctat atatgcattt
    11941 agaagattat ggattaactt tgaagtatat tataggtcaa attaaagaag gaatttgtgc
    12001 tataaataac gaaggtgttg ttatcttgtg gaataagttt atggaggaaa ggtatgatat
    12061 aaagtctgaa gatatagttg gtcgaccgat gaatgaattt ttggaaaata ctatttcaga
    12121 aaaagtacta aatagtaaag ttggaatgag tgacttgtat tttacagata aaaaagaaaa
    12181 tatgtatgca ttagttcatg caaatcctat attttataaa gaagaattta tcggtgttgt
    12241 atgtacagaa gttgatgtta cagaagctaa gatattagct cttgaacttg aaaaagtaaa
    12301 tgatacatta aaatatctaa agaacgaagt caaaaattta tctaaaggta gttttgataa
    12361 gattttaggt aaaagttata aattggaaaa atcgaaagcg attgcaaaac aagtggctag
    12421 aacaaatagt agtatattta tttggggcga aagtggtaca ggtaaagaag tatttgcaag
    12481 agctattcat gattatagtg agagaaaagg gcaatttata cctgttaact gtagtgccat
    12541 accaaatgag ttatttgaaa gtgagttttt tgggtatgaa tcaggtgcat ttacaggagc
    12601 aagtaaaaag ggtcgaatag gtatatttga acttgcaaaa gatggaactg tatttttaga
    12661 tgaaattgcc gatttacctc ttagtatgca agcaaagttg cttagagtat tacaggaaaa
    12721 agaaataaga agagttggtg gagataccac aataaaaata aatcctagaa taatatcagc
    12781 taccaataaa gatttgagta aaatggtaaa ggcagaaaaa tttagagaag atttatacta
    12841 tagattaaat gttgttgaaa taaagattcc tccacttaga gagagaaaag aagacatagg
    12901 attattggtt catagctttt tagaggagat atgtaaacaa aataataagc ctgttcttac
    12961 aattagcaaa gatgtaatag atatatttca gaattataga tggaaaggta atattagaga
    13021 attaaaaaat acgattgaaa atattgttgt attgtcacaa aattctaaaa tagatgtgga
    13081 tgatgtacca agttatatga tggattctac aaataatagt actgaagaag aagagtatcc
    13141 tttagattta acgaaggcaa ctcaaaaaat tgaaataaag aatataacca aggcacttaa
    13201 aatgtctaat ggaaataaag ctaaagcagc taagatatta aatataccca gaacaacttt
    13261 gtattataag atagaccaat acaaaataga tgtgtctaaa atatgacaca tgactaaatt
    13321 ttgacaaaat gataaacttt aatttaaaac ctagtaaagc caacacttgt ataagtgttg
    13381 tgtatataga tgtgttaaaa aaaatgaaaa agtgttgatt aattgacact ttttttgttt
    13441 gagaaaatgt ttacaaatac aaaaaataac atattttaaa taaatattta tataatattt
    13501 ggctaaaaat agcgatagat gaagaatcta ttatagaaaa aatctttttg ttaataagtt
    13561 ggcataggaa ttgcttataa tataaagtga ctttaagtga gaaaaaaata atattaatca
    13621 taacaaatta tgtaggtttt aatttactta atttctcagt taaggggtta cctgttgagg
    13681 aattgagatt taaaataata aataagaaaa taatgtaagg aggtatttta tactatgtca
    13741 ataactttag aaacagctca agcccatgca aatgacccag cagtttgttg ttgtagattt
    13801 gaagcgggaa caattatagc gccagaaaac ttagaagatc cagcaatatt tgcagactta
    13861 gaggattctg gattattaac aataccagaa aatggattaa ctataggtca agtactagga
    13921 gctaagttaa aagaaacttt agatgcactt tctccaatga ctacagataa cgtagaagga
    13981 tacaaagcag gagaggctaa agaagaagta gtagaagaaa cagtagaaga agcagctcca
    14041 gtatcagaag cagcagtagt tccagtaagc acaggagttg caggtgaaac agttaaaata
    14101 cacataggtg aaggtaagaa cataagctta gagatacctt tatcagtagc tggtcaagca
    14161 ggagttgctg ctccagtagc aaacgttgct gctccagtgg caagtgcagc agcagaagta
    14221 gctccaaaag ttgaagaaaa gaaactttta agaagcttaa ctaaaaaaca ctttaaaata
    14281 gataaagttg aatttgctga tgaaactaaa atagaaggaa ctactttata catcagaaac
    14341 gcagaagaaa tatgtaaaga agctaatgaa actcaagagt tagttgtaga tatgaagtta
    14401 gaaataataa ctcctgataa atatgaaact tacagtgaag ctgtattaga tatacaacca
    14461 atcgctacta aagaagaagg cgaattaggt tcaggtataa ctagagttat agatggagct
    14521 gtaatggtat taactggtac agatgaagat ggagttcaaa taggtgaatt tggttcttca
    14581 gaaggtgagt taaatactac tataatgtgg ggtagaccag gtgctgctga caaaggtgaa
    14641 atattcatca aaggtcaagt aacaataaaa gcaggaacta acatggaaag accaggacct
    14701 ttagctgctc accgtgcatt tgactatgta actcaagaaa taagagaagc attaaagaaa
    14761 gttgacaact ctttagtagt tgatgaagaa gtaatagagc aatacagaag agaaggtaaa
    14821 aagaaagttg ttgttataaa agaaataatg ggacaaggtg caatgcatga taacctaata
    14881 ttaccagttg agccagttgg tacattagga gctcaaccaa acgttgactt aggaaacatg
    14941 ccagttgtat tatctccact tgaagtatta gatggtggta tccatgcatt aacttgtata
    15001 ggacctgcat caaaagaaat gtcaagacat tactggagag agccattagt aataagagct
    15061 atggaagacg aagaaataga tttagtaggt gttgtatttg ttggttctcc acaagtaaat
    15121 gctgagaaat tctatgtatc taagagatta ggtatgttag ttgaagctat ggaagttgat
    15181 ggagctgtag taactactga aggtttcgga aacaaccata tagatttcgc atctcacata
    15241 gagcaaatag gtatgagagg tataccagta gttggtgtaa gtttctcagc tgttcaaggt
    15301 gctctagttg ttggtaataa atacatgact cacatggtag acaacaataa gtctaagcaa
    15361 ggtatagaga atgaaatatt atctaacaac actttagctc cagaagatgc tgttagaata
    15421 atggctatgc ttaaaaatgc tatagaaggt gtagaagtta aagctcctga aagaaaatgg
    15481 aatccaaatg ttaaattaaa taacatagaa gctatagaaa aagttacagg agaaaaaata
    15541 gtattagaag agaatgagca atctctacca atgagtaaga agagaagaga aatatacgaa
    15601 aaagacgaaa actaaaattt agatactaac taagatttag acaataacat aaatttagat
    15661 ccaagtttaa aacagtatag agaggtagaa ttataatgga taggttaaaa tatatctcat
    15721 cagagacttt ttatgaaggt attatagttg acatcaaagg cggtggagtg actatagacc
    15781 taaaaggtag acttggacaa tttaaaatac ctaatagaat gcttataact gactacgaac
    15841 ttaagatagg tcaagaagtt ggattcatgc taagctatcc tgaggtatta agtccagagc
    15901 ctaatcaaga gtatgtagaa aatattagga gagaaaaaga aaaacaagca gaaatgcaat
    15961 caaaacaaga agaaaaataa taaataatcg tttgaaaata gaagggagag gaaatatatg
    16021 agccttacaa cagtacaagg acttcaatct gaaatattcg ttccaataac acctcctcca
    16081 gtttggactc ctgtaactaa agaattaaaa gatatgacta tagctttagc tacagcagct
    16141 ggtgttcatt taaaatctga caagagattt aatctagcag gagatactac atttagagct
    16201 atacctaata cagctacagt tgatgaaatg atggtatcac atggtggata tgacaatgga
    16261 gatgtaaaca aagatataaa ctgtatgttc cctatagata gattacatga attagctgca
    16321 gaaggattta tcaaaggagt agctcctatg cactatgcat tcatgggtgg tggaggaaac
    16381 caacatgtct tcactgaaga aactggtcct gctatcgctg ctaaacttaa ggaagaggga
    16441 gtagacggtg tagttatgac agctggctga ggtacttgcc atagaactgc cgtgatcgtg
    16501 cagagagcaa tagaggaagc tggaatacct acaataataa tagcagctct tcctccagta
    16561 gttagacaaa acggaactcc tagagcagtt gctccattag ttccaatggg tgctaatgct
    16621 ggtgaaccac ataatataga aatgcaaaca catatattaa gagatacatt agagcaatta
    16681 gttgcaatac catctgctgg taagatagtt ccattaccat acgaatataa agctcacgtt
    16741 taaaatgtaa tttatatttg aaaatataga acccttctcc tacacggtta ggagaggggt
    16801 tttaagaaca aaggtggata ttatggaaga aaaaataatg agaagacttg ttataaaacc
    16861 gtttcatatg aatgaagtta atttcggttc aaaaacttct ataaagaaag atgtacttac
    16921 aatagattta tcaagtatag atgaaataaa agaaagagaa gagttaataa cagacataaa
    16981 agtagacatt ataaaacctg gagattatga cagagaaatt aatactatta tggacattat
    17041 accaatatca acaaaagttt taggcagact gggagagggt attacacata ctttaacggg
    17101 tgtatatgta atgttaactg gtgcagatga agatggaaat caaatgcatg aatttggttc
    17161 ttcagaagga attttgaaag accaaatggt atttgggaga tatggaactc catcagttga
    17221 agattatata atccatgtag atgtaacttt aaagggaggt ttaccttttg aaagaacact
    17281 tccacttgca gcattcagag catgtgatga ttttatacaa gaaataagag cgtctttgaa
    17341 aatggaagac ggaagaaatg ctactcaagt tcgtgaatat tttgacaaaa ttcgaccaaa
    17401 tgcaaaaaag gttgtcatag taaaacaaat agcaggtcaa ggtgctatgt atgacaatca
    17461 gttattctca aaggaaccta gtggatttga aggaggaaca tcaattatag atatgggaaa
    17521 tgtacctatg attatatctc ctaatgaata cagagatggt gcccttagag ctatgactta
    17581 agagaggtgg atattatggg aataggacct tcaacaaaag aaacatctct tcatcacttt
    17641 agagacccac ttttagacat agttgaaagt gataaggatg tagatttact tggagtaata
    17701 gtagtaggaa ctccagatgg aaatgaaaat aaaacctttg tgggacaaag aacggccgct
    17761 tggctggaag ccatgagagt agatggagct atagtttcat cagatggttg gggaaactca
    17821 catgttgact acgctaacac atttgaggaa ataggaaaaa gagatatacc tgtagttgga
    17881 gttacattta atgggactca agctaagttt gttgtaagca atcaatatat ggataccata
    17941 gttgatatga acaaatcaaa agaaggtatt gagacagaag tagttggaga aaacaacaca
    18001 aatgaaatag atgctaaaaa agctttggca tttttaaaac ttaaaatgag aaaacatgga
    18061 taaaaaattt aagtaaggga atgagttttg tgggaatttc tacatcaatg aaaaacacat
    18121 cacttcatat atttagagac ccgttactag atttgataga taatgattct gacatagact
    18181 tgttaggagt ggttgtagtt gggacatcag agcacaatga atggaaaaca tttttagcaa
    18241 ctagacttgg aagatggatt gaatcattgc gacctgatgg agtgattata actttagata
    18301 tggcaggaaa ccagcacatt gattttacaa atgctatagc agagtttgta aaatcagata
    18361 tacctacagt aggtcttact attatgggag cagatggatt agtaattacc aatccatagt
    18421 tggataaagc taccataatt gattataaaa agacaacagg ctacatagaa acagaagtag
    18481 ttggagacaa tcacatggat gaagttgatg ttaaaaaagc attggctttc ctaaaattaa
    18541 aaatgcgtaa agacgcaaaa taaacctaag ggggaatttg atatgaaatt tagcagaagt
    18601 atacaagcta tagactctca tacagcaggt gaagcaacta gaatagttgt aggtggaata
    18661 cctaacataa aaggaaattc tatgcctgag aaaaaagaat atttagagga aaatctagat
    18721 tatttaagaa ctgctataat gttagagcca agaggacata atgatatgtt tggttctgta
    18781 atgactcaac cttgttgccc agatgctgac tttggaataa tcttcatgga tggtggcgga
    18841 taccttaaca tgtgtggcca tggtacaata ggagctatga cagcagctat agaaacaggt
    18901 gtagttccag cagtagagcc tgtaactcat gtagttatgg aagctccagc aggaataata
    18961 agaggagacg ttacagttgt agatggaaaa gctaaagaag tatcattctt aaacgtacca
    19021 gctttcttat ataaagaagg tgttgaagtt gacttaccag gtgttggaac tgttaaattt
    19081 gacatatcat ttggtggaag cttctttgct ataatacatg caagtcaatt aggtttaaaa
    19141 atcgaacctc aaaatgctgg taaattaact gaactagcta tgaaacttag agatataata
    19201 aatgagaaaa tagaaataca acatccaact ttagctcata taaaaactgt agacttagtt
    19261 gaaatatatg atgagccaac tcatccagaa gctacttaca aaaatgtagt tatatttggt
    19321 caaggtcaag ttgacagatc tccatgtgga actggaacaa gtgctaaatt agctacttta
    19381 catgctaaag gtgaattaaa agtaggagaa aaattcgtat atgaaagtat attaggaact
    19441 ttattcaaag gtgaaatagt tgaagaaact aaagttgcag atttcaatgc tgtagtacct
    19501 aaaataactg gttctgctta tataactgga tttaatcatt ttgtaataga tgaagaagac
    19561 ccacttaaac atggatttat tcttaaataa gtaataaata aattaggaaa ttaaaataga
    19621 atagtagcca cttgtcggtt gctattctat agcttttagg ctataagatt cagaatatat
    19681 gaaaaaataa aaaaatagga ggatggatta tggtagcaat cttaaaggca ttatatgtag
    19741 tattcgcagc aatctttgca gttgtgtttg gtaaagacgt agctaaagca aacaaagagg
    19801 ggaaactaga agaacaaagt actccaaaag ttgctgtaac aggatttata acagacttct
    19861 ttgatacatt aggaataggg tcatttgctc caacaatagc aatgtcaaag gctttaaagt
    19921 taaatatacc agataaaaaa atgcctggta cattaaacgt agcacatact attccagttg
    19981 ttacagaagc attcatattt acatcaatca taccagttga tggtgttact ttagtatcta
    20041 tggttgtggc agcagcagtt ggttcatata taggtgcagg aataatagct aagatggacg
    20101 agagaaaaat acaacttgtt atgggtgtaa ctttagcatt aacagcaata ttaatgttat
    20161 taggtcatcc ttggattaac gtattaccag gtggaggaaa tgaattaggt cttactggtg
    20221 ttaaattagt aataggtgta ataggtaact ttatactagg agctttaatg acagctggta
    20281 taggtttata tgctccaggt atggcaatgg tttatttctt aggaatgtct gcaaaagttg
    20341 cattcccaat agttatgggt tcttgtgcat tattaatgcc agttgcaagt atgaaattca
    20401 taaaagaaga tgcatatact aaaaaagcat cagttataat agctatatgt ggtttaatag
    20461 gagttttcgt agctgcatat atagtaaaaa ctctaccaat ggatatatta aaagcattag
    20521 taatagtagt tatagcttat acttctgcta caatgataat ggctgcaaat aaaaacaaaa
    20581 agactgctta gttaaagact acttagtgtt tattaaatat tacagctaat aataaagatt
    20641 ataaactgct ttaaaatatt gaattaatat tttagggcag ttttttattt actaaattaa
    20701 tataaagcaa ttaacatgcc aattatgtaa tatatatagt gatttagtag atttaatgta
    20761 aaaaacgttg tatttttaaa gaataaagca taatttaaag ctaaatattt aaattttata
    20821 atcaataagt tcaataaatg ttcatatatt aatacagatt aataaaaata taacctataa
    20881 taagtctaat ataacttata attaagaaaa ataagtttat aatgactcaa tattcatctg
    20941 aattatttga ataaatttaa ttcgttgaag ttgcttatat agagtgaata aatttaagtt
    21001 atatatgact tattaactat ataataggat ttttataatt aatacaaaac tgaaataggt
    21061 agtttaatta gtatatgtgg tacaaaaaga taataatttt ataattataa aagtgaaata
    21121 ttaaatgaaa tttataacta aataaaaact tttaaacagc aatcaaagat ttgtaataaa
    21181 atacatccct tataaatata tttattatat aagctgatac cagaaatata agaattaaca
    21241 attgtggagg gataaaatat gatagctgtt aaagatgaga ataacgtagt aaacttaaga
    21301 ggggagttag acaataagct agaatttagc catgagatat ttggagaaaa attttataat
    21361 atgaaaataa aaataaacag actaagcgat tcttttgata tacttccaat gactgtatca
    21421 gaaagacttc tccaagatat tgaccttgat aaacaaaatt tagtcaatgt cgtaggccaa
    21481 ttaagatcat ataacaaaac attaaataat aaaaatagat tagtgcttac agtgtttgtc
    21541 agagaaataa aaagcataga cgaggaaaat aaagacccta atagtatatt tttagatgga
    21601 tatgtatgta aggaacctgt gtataggaag acacctttag gaagggaaat aaccgattta
    21661 ttagttgcta taaacagacc ttataataaa tctgattata taccatcaat agtttggggt
    21721 agaaatgcta aatttgcaaa gaatctaaag gttggtgata gaatacagct ttggggtagg
    21781 gttcaaagta gagaatatga gaaaaaaata gatgaaaata atgtggtcaa aaaaatggca
    21841 tatgaagtat ccatatcgaa aataaaaaaa ttggatgaaa ataacaatga ataaacataa
    21901 aaaatagact gatttttatg aataaaatcc taataaattt ggtataatat catattaaaa
    21961 tgtataaaga ttgtttaaaa aaatactaat gaaatatctc ttgaatagtt gctcgccatt
    22021 tattataatg taatctgtac ataatttata attgaggaaa tgaagaggtg aagcattgtg
    22081 aaaagcatat tatgtcagat aaataaacag ccggttaaag ctaaatatac atctgatgaa
    22141 ttagaatgtt ttttggatac aattgagtat aatgtaggtg ataaaatatt gcttgttggt
    22201 catataggaa acctaggcaa gagattgaga ggtcttggaa cttctgtaac tatactggag
    22261 aatagtaatt atgaagatgt ctgttattct ctagtgtata atgaaaattg caatgtagtt
    22321 aaaggtaagt tagagtttct accatttgat gataatcagt tcaacaagat aataatagtt
    22381 gaccaattta atgttattac agattgtgaa aaagcttcat ctgaaataca aagagtgtta
    22441 aagggcaatg gagaggttat attagaggat ttaaatttaa agaatttaaa agttaagtta
    22501 aactatctta aacataaatt ttgtggttct gttgcaaaga ttcactatcc acatgaagta
    22561 tttaatatat tttcaagatt aaactttgat ggtatgatta aagagtcaaa taaattaaaa
    22621 tatatttatg tgggaaaaag aagataaatg agttaaaata taaatatgga tataatataa
    22681 aagactaggt taagcctagt cttttgttat aaggagatgt ttagatggaa ataaattatg
    22741 agttaataat aattgttatg ctctttgtaa tcctgatgtc aatccaattt actttaaata
    22801 agatatactt gattcttaaa gaaataagac aaatacttat gttaaagaaa aataaggaat
    22861 gatgattatg ataggtttag aatatataaa atctgatatt caaaatatag ctgaagctat
    22921 agtatcagta ctcaatatag atgtaactat agtaaataag gagttattta ggattgcagg
    22981 tacaggagta tatatagaca aaataggtga gaaagtagat aaatatacgg cttttaaaaa
    23041 atcacttaca gagcagatta caatactaat tgatgaccca aagagtagtg atatatgtag
    23101 ggaatgctat aaaagtgggg cttgtgtaga gtttgcagag gtgtgttgtc ccattatatg
    23161 tgatggagtc tctcatggtg ttataggcct tatagccttt acaaaggaac aagcacagat
    23221 tatagaaaat aataaaagtg gtcttataaa ctttttaggc aaaatggcag acttaatatc
    23281 taataaatta aaagctcaaa ttaaaactta tgagcttgaa ttagaaaaga aaaaattaga
    23341 gacactgtta aacaatatgg acaaagctgt tgtgtctatt gatgtggatg gaaaaattga
    23401 taaatataat tcaaaattta aagagctttt caatataaag gatagtataa ctggcaaaaa
    23461 catatttgtc gaattagatt ttataaagaa accttctata aataacttta agaaagacaa
    23521 atcctgtagt tttttttata aaagatacgg atatgattcg aagggaatat acaacatcaa
    23581 taaaatagta ttaaaaaatg agttaaaggg atatgttatt gattttatag ataaaagaga
    23641 tgctataaaa aactacaata agatgaataa agattataga ataaaattgg aaaacataat
    23701 tggagaaagt gtagctataa gaaattctaa aaaggaagcc ctaatagctt ctaaatcaac
    23761 atcaacagta cttattactg gggaaagtgg aacgggtaag gagctatttg caagagccat
    23821 acacaaccat agcaatagag tagataatcc ttttatagct gtaaactgtg ctgctatacc
    23881 agacaattta ttagaaagtg aattatttgg atatgaagag ggagctttta ctggagctaa
    23941 aaaaggtgga aagcttggaa tgtttgaagt agctcataag ggaagtatat ttttagatga
    24001 aataggagat atgagtttgc atttacagtc aaagttattg agagtattac aagaaaagga
    24061 acttaataaa attggaagta aatcaaatgt ttcaatagat gtaagaatta ttgctgctac
    24121 aaataaagat ttagaaaaaa tggttcaaaa tggcactttt agagaagatt tatactatag
    24181 attaaatgtt atacctataa aattaccaag tttaagagag agaaaagaag atatcccact
    24241 tataatcaag catatggtta aagagtattc aaaaaaatta gataaaaatg ttattgacat
    24301 agatagcagg gttgttgatg ctatgatgga atataagtgg ccagggaata taagagagtt
    24361 gcagaatatt attgaatata gtgtgaatat gtcttcttct tcaataatta caatgaatgt
    24421 aattcctcaa aaaattaaga atacctctgt agaagagtta gaagttaaaa gcgataggat
    24481 aattccactt gatgaactag agaagattga gataataaaa gctttaaata agtacaaaga
    24541 ttataaaaaa gataaagaat taacagctaa agcacttgga atatcaagag ctacattata
    24601 tagaaaaatt gaaaaataca atataatttc atagtaatat aataaaaagc tatataaaat
    24661 ttaaattttt ctaaattcat aactttaaag aaagctttaa acttatacta taagtgtttt
    24721 gcagaatctt tttttatgaa ttaaaaaatg gtttttataa gttaaaaaat aatatatttg
    24781 agccgtctca aaatgatata gaatctcatt ttgagacttt tttttgtctt tttgcgaaat
    24841 tgtcatatgt ttctccattt taaagaatat aaatactcta tacaaataaa aaaaatacat
    24901 aaatagaggc agtcatacca atggttatag aatataagac taaaaatata aaaagatata
    24961 aaaaatatgg catgtatttt gctataaata tagataagaa attatttaat taattatttg
    25021 agtactaaat ctaaacttaa ttgggaggtt tatatataat gagagatata agaaaagaat
    25081 tagtggaaat gttaaaggca gaagttaaac cagcagtagg gtgtactgaa ccagtagcct
    25141 tagctctagc atgtgcaaag gcaaaggaat tattaggaga agaaatagtt gaaaatcgta
    25201 tgttagttag tcctagtatt tataaaaatg gtatgtgcgt aggtatacca ggtactgaaa
    25261 gattaggatt aaaaattgca gcagctctag gtatagtagg tggacattct gaaaatggat
    25321 taagtgtgtt agaaactcta acaaaagagg aagttaaaat agctgaggat tatatggata
    25381 atactccact atcaataaca cctgctgata caagagagaa agtatttata gaagttgtgt
    25441 taaaaggaaa aaatcatatt gctaaagtga gaataagaac taaacatgat aattttacgt
    25501 tcttagaaaa agatggagaa gtattattag acaatgaacc aaaagtatca gcttcaaatg
    25561 atgcggcaga aaaagctgaa agtttaatgg atacagtaac tatacaagaa ttaataaaaa
    25621 atgtagaagg aattgatttt aaagatatag aatttttact agatggagta aaaatgaatg
    25681 aagagatggc tgaatatgga ttaaaacaaa aaactggtat tggtgtagga tatggaatta
    25741 aaaagtctat agaagaaggt cttttaggta atgatgttat aaattatgca atgatgttaa
    25801 ctgctggagc ttcagatgca agaatggcag gggtaaaaat gcctgttatg agttcaaatg
    25861 gaagtggaaa tcatggatta acagcaattc ttccaatcgt tgcttataat aaaaaattcc
    25921 cacaatctga tgaaagacta gcaaaagctt tagctatatc tcatctagta actggttata
    25981 ttaagaacta tacaggaaga ttatctgctg tatgtggatg tggtgttgct gcttctactg
    26041 gagcaactgc tggtatctct tggcttatga atggtactga aaagcaaata gaaggagcta
    26101 tagaaaatat gatagctgac ttaagtggaa tgatatgtga cggtgcgaaa gctggttgtg
    26161 cattaaaatt atcttctgca gcatctgcag ctatacaaag tgctataata gctaagcaag
    26221 attgttttgt accaccacta aatggtatag ttggttcaag tgttgagcaa agtatacaaa
    26281 acttaggtag agtaagtgac aaaggtatgt ctataacaga tgagataatc ttaaatgtaa
    26341 tgaatgatat gaataaagtt gactagtact ttataatatg ttttgtatta tgaggtataa
    26401 caaaaatagc ataaataaat ttaattagta ccctctaata aaatatgatt atgtataaat
    26461 ttatgtataa tagaaaaaac ttgttaatgc aagttttttc tttttttgtc taaaatatat
    26521 agtatgtaat ttagtgtgga tatatgaact acttaaaata taagatacat tgttaataat
    26581 tgttgaatga acataaaaac tcaataatat tgactaatat tgaataagag tattgaaaaa
    26641 gtgagcaatc tcttataaaa ttaagaagga ttattacaat tggaggtctt tttatggata
    26701 tagaaacaaa aaaatgggaa gtattgtatt cagaagaaaa aattaaagat aaattaaggg
    26761 aattaggagc aattatagaa aaagattata aagataaaaa tcttatggta gtttctctat
    26821 taaaaggtag ctttatattt tgtgcagact tagttagaaa tataaactta ccacttagag
    26881 ttaattttat gactacatct agttatggaa acaatgaaga aagtactgga aaggttaaag
    26941 tagtttcaga tgtgactact gatatagcag gatatgatgt tttggttgta gacgatatta
    27001 ctgattctgc acttactatg gattttgtgt taaaacatct aaaagctaaa aatcctgcta
    27061 gtttaaaatg ctgtgttctt ttggataaac caagcagaag aaaagtcgat ttagtgccag
    27121 attattgtgg atttgaaata gaagataagt ttgtggttgg atatgggttt gattttggtg
    27181 attattatag aaatgttcct tatatattca atgttactga tgaagataga taagcaatta
    27241 tataattttg tggatgcctt aatatgattt ttattaatcg tgttgaggtt tttttattta
    27301 aaaagtaatt aaagtagtat taaattaatt ttatgcaatt taattatcta ttttttatag
    27361 cataataaaa aaattttaaa taattgatgg gaaatgagtt ttttaattgt attaataatt
    27421 gtaaaagagt actaataatt gtaaaagatt ttacaaaaaa gtaatgaaat ttaagaatca
    27481 aagcatatat gttgatataa gcaaatagat acattatcac ataagaaatt gtcgattcat
    27541 ataattatat agagtaatac tcaatattta tagagtatta ctctaacttt aaaaaaggag
    27601 gattaattat atgagtgata tttcaggtcc aagtttatat caagatgtag gtccaacagg
    27661 gccaacaggt gctactggtc caacaggacc gacggggcct agaggtgtaa ctggagcgac
    27721 cggagcaaat ggaataacag gaccaacagg aaatacagga gcaactggag cgaatggaat
    27781 aacgggtcca acaggaaata tgggagcgac tggaccaaat ggaacaacag gttctacagg
    27841 accaacagga aatacaggag cgactggagc gaatggaata acaggtccga cagggaatac
    27901 aggagcaacc ggagcaaatg gaataacagg accaacagga aacaaaggag caaccggagc
    27961 aaatggaata acaggttcta caggaccaac aggaaataca ggagcgactg gagcaaatgg
    28021 aataacaggt ccaacaggga atacaggagc aacaggagca acaggaccaa ccggactaac
    28081 tggagcaaca ggagcaaccg gagcaaatgg aataacagga ccaacaggaa atacaggagc
    28141 aaccggagca aatggagtaa caggtgctac aggcccaaca ggaaatacag gagcaacagg
    28201 tccaacagga agtataggag cgactggagc aacaggaaca actggggcaa caggcccaat
    28261 aggagcaaca ggagcaacag gagcagatgg agaggtaggt ccaacaggag cagtaggagc
    28321 aacaggtcca gatggtttgg taggtccaac aggcccaaca ggcccaaccg gagcaaccgg
    28381 agcaaatggt ttggtaggcc caacaggccc aaccggagca accggagcaa atggtttggt
    28441 aggtccaaca ggagcgacag gagcaacagg agtagctggg gcaataggtc caacgggagc
    28501 agtaggagca acaggcccaa cgggagcaga tggagcagta ggtccaacag gagcgacagg
    28561 agcaacaggg gcaaatggag caacaggccc aacgggagca gtaggagcaa cgggagcgaa
    28621 tggagtagca ggtccaatag gtccaacagg tccaacggga gaaaatggag tagcaggagc
    28681 aacaggagcg acaggagcaa caggggcaaa tggagcaaca ggcccaacag gagcagtagg
    28741 agcaacggga gcaaatggag tagcaggagc gataggacca acaggcccaa ccggagcaaa
    28801 tggagcgaca ggagcaacag gggcgacagg agcaaccgga gcaaatggag caacaggtcc
    28861 aaccggagcg acaggagcaa caggagtgtt agcagcaaac aatgcacaat ttacagtgtc
    28921 ctcttcaagt ttagtgaata atacattagt gacatttaat tcatcattta taaatggaac
    28981 taatataact tttccaacaa gtagtactat aaatcttgca gttggaggga tatacaatgt
    29041 atctttcggt atacgtgcca cactttcact tgcaggattt atgtcaatta ctactaactt
    29101 taatggagta actcaaaata actttattgc aaaagcagta aatacactta cttcatcaga
    29161 tgtaagtgta agtttaagct ttttagttga tgctagagca gcagctgtta ctttaagttt
    29221 tacatttggt tcaggcacga caggtacttc tgcagctgga tatgtatcag tttatagaat
    29281 acaatagttt atatgatgaa aagattataa aataataaac aatatgattt catataccaa
    29341 taaatagaat aatatttaat aggtttatat gatgaaaaga ctataaaata ataaacaata
    29401 tgatttcata taccaataaa taggataata tttaataggt ttatatgatg aaaagactat
    29461 aaaataataa acaatatgat ttcatatacc aataaattag gataatattt aataggttta
    29521 tatgatgaaa agattataaa ataataaaca atatgattct atataccaat aaataggata
    29581 atatttaata ggtttatatg atgaaaagac tataaaataa taaacaatat gattccatat
    29641 accaataaat aggataatat ttaataggtt tatatgatga aaagactata aaataataaa
    29701 caatatgatt tcatatacca ataaataaga taatatttaa gaaaaatgat tatatttaaa
    29761 aggtaagcat aaaatttata aacttttaga atagaaatct caatcaatta gatattcaaa
    29821 ttgatgaata tgaataccta aatagattga gatttattat gtacaaaact tatcctaata
    29881 tatctgacat tttataaagc ccagattgct taccaattaa aaatttagct gcaactatag
    29941 agccgtttgc aaatacttca tcagattgag aatgatggct taatgtaaga acttcattat
    30001 cacctgcaaa tacaacatca tggtcgctga ttatattgcc acctcttata gagtgtattc
    30061 caatttcatt tggttttctt ttacaatctc taccatatct accatgtgta ttttcacttt
    30121 caggcaagac ttctctaatt gcattagcta tcatagtagc agttccacta ggggcgtctt
    30181 cttttctatt gtgatgtttt tctatgattt caatatcaaa accttctaac atctttgaag
    30241 catccttaac taattttatt aatatattta ctccaagaga tgtatttgat gataataata
    30301 taggaatgtt ttttgatgct tcttctattt tatttaagtc attttcgtca tatccagtag
    30361 tagctaatac tacaggtgta ttatttttta gagcatatga caatattggc tctaaagtat
    30421 catgatgtga aaagtctata attacatcag ttttttcagt tacatcagtc attgttttgt
    30481 aaagctttgt atcactatga tgaccttttt catcagcaga cctagctaca ccacaaacca
    30541 actctaattc attatctttt tttacacatt ctgctaaaac tcttcccatt gttccattat
    30601 agccactaat tataactttc aacataaatt cctcctatga aattaataaa aatttgttat
    30661 atttctataa gtttatttta tcactaatat aatttatata aaataatatt agtgataata
    30721 agcttacaat ttatcttaca ttaaaaaatt taagtggatt tttcaaaata tagataaatt
    30781 tctttttcat tgtttaaatg ataaaaatat atttgacttc ataccaaaaa gagtgcccca
    30841 tgaactaaaa agttaatttt gaaataccat attcatatat catatgattt atttggaaat
    30901 taatattaat acattaaaat aactaaatac atgtatgcat aaagatgtat aaaaaatata
    30961 taaacatata gtattaattt taaattcaac aatttaattg ttaaaagtgt tattattaaa
    31021 ttagaaatat cttaacttaa tatactgaga tgggagtgat agatatgtta aaagaagaaa
    31081 aaacttatca agagaaagac gcaaaagtat tcaatggagt ggcagctttg ataatgattt
    31141 tattattttt agtagtttca ataggtatca tggtttttgg gatagtaaaa cttgatagtg
    31201 gatttactgg aataggttca cttatgttaa ttttgggact tgtatttata gtagtagatt
    31261 ttatcctatt ttttgggcta aaaatgatta atcctaaaga agctatagtt ctagttttgt
    31321 ttggtaacta ttatggaact ataaaaaaag aagggtacta ttgggtgaat ccattttgtt
    31381 cagcaataaa cccagcagta tcaagaatta atgtatcgaa atcttcatct gatgaaaagg
    31441 tagatatatc aactaattca aggggcaaaa aagtatcttt aaaaacaatg actcttaata
    31501 atgaaaagca gaaagtcaat gatttattgg gaaatccaat tataatagga gtggttgtaa
    31561 tttggaaggt tatagatgca acaaaggcag tatttaatgt ggataattat aatacattct
    31621 tatctattca gtgtgattct actattcgca atgtttcaag actttatcca tatgatgtat
    31681 ctgaagatgg agatgaaaaa tctcttcgtg gtagtagtca ggaaatagca gatagattaa
    31741 aagatgaatt acaatcaagg gttgacattg caggaattga agtgtgtgaa gtgagaatta
    31801 ctcatctttc ttatgcacca gagattgcag cagcaatgtt acaacgtcaa caagcagagg
    31861 ctataatagc agcacgtaaa aagattgttg agggggctgt aagtatggta gagatggcat
    31921 tgactaattt aagtgaaaat aatgttgtga ctttggacga agaacgtaaa gcagctatgg
    31981 taagtaatct gttagttgtg ctttgtggca ataaagatgc acaaccagtg gtaaacagca
    32041 gttctattta ttaaattata aaaagtttaa tagtttattt tattgatata tagaaaattt
    32101 agtagttcat tttattaaat tatataaaga ttaatggttt gctttattga attataaaaa
    32161 gtttaataat ttattctatt gatatataga aaatttagta gttcatttta ttaaattata
    32221 taaagattaa tggttttcac tttattaaat tataaaaagt ttaatagttt attacattga
    32281 tatattgaaa aattgaagga aataaaaata cttgtcagca agaaataaaa atgatataag
    32341 aatgaataag agaattgtaa aaaaataaaa tgattataaa taaaagataa aaatattgta
    32401 aaaaagaggg tgcctctggt gaattaaatt cacacagaga caccttttta attaattttt
    32461 taaattagta tattattgtt taattaatag catagtacta tttaattaat ctaaatttct
    32521 aaggtcttcc ataagcttag ttttgtcagc cgttttttca tctttcattt ttataacttt
    32581 agcaggagaa ccagcaacaa cggcaccagc ttctacatca gtagttacaa cagcaccagc
    32641 tgcaacaaca gcacctttac cgattctaac accttcaaga ataactgcat tagctcctat
    32701 taaaacatca tcttcaacta taacaggagt agcagaaggt ggctctaaaa caccagcaac
    32761 aacagcacca gcacctaagt gaacattttt accaagagtt cctctagctc caataacagc
    32821 attcatatct accatagaac cttcaccaat aacagctcct atatttataa cagctcccat
    32881 cattacaaca gcattttttt ctatagtaac catgtctctt attattgcac ctggctcaat
    32941 tcttgcatgt tcacttaaag tattttttag aggaatagca gaatttcttc tatcatattc
    33001 tacatgagta tctgttatat catttccatg tttatctaat acttccatta tatcctcata
    33061 gtcacctaca aatatataag aaccattact tccaaatacc ttaaatttat cagttgattg
    33121 gaagtgtaaa gagttagtat ttacatatac cttaacaggt gttttctttt taacttcttt
    33181 tatatacctt gctatttcat aagcatcgtt taaatttacc atttgttaat tctccttgta
    33241 tttcattata tttcttttat tatatactta tttgtcaatt ttagtatata cttacttctt
    33301 attatttata ttttatttta gttagctttt attgtataga catagtatta aataaattta
    33361 ttatatatgt ttgatttgta ttgcatatta ttatatatat attgtatatg tttaatttat
    33421 attgtgtatt attatattta tactattatc ccaacatgct gtccatatta taaaatcctg
    33481 gtttttgctt aactaagtat ttggcagcag ctatagaacc acttgcaaag ataccacgag
    33541 attgagcttg atggcttatt gtaagaacct cattgtctcc agcaaataga gcatcatgtt
    33601 cgccaacaat atttccacct cttatagcat gaataccaac ttcatttggt tgtctttttg
    33661 cactacgacc atatctacca taattatttt caacgtttgg caaaacctct tttatagcgt
    33721 tagcaatcat aacagctgtg ccacttgggg catctacttt tctgttgtga tgtttttcta
    33781 ttatttctat atcaaatcct tctagtaatt tagctgcatc tttaaccaat tttactaata
    33841 catttacacc aagagacata ttatatgatt ggaatacagg aataacttta gccgcttcac
    33901 gtattttgtt catttcgtca tcattatatc cagtagtagc aattactaaa ggtgttttag
    33961 tctttaaaac gtaagataag atattatcta aattagagtg atgagaaaaa tctataacta
    34021 catcagcttc ctcaactata gtactcatat cttcataaat tttaaggtcg ccttcatagc
    34081 tatccagacc tctagctgca acacaaacca attctaattc attatcttct cttatagtat
    34141 cggctaaaat cttacccatt tttccatcat aaccagttgc tataactttt aacataattt
    34201 cctcctatga ttaagggcta acttttgacc aaacttactt tttaccatgc attaatcttt
    34261 actatgcatt aacttttagt ccaaagttaa ctaattcttt ctttaatact tctaaatttg
    34321 ctgggtccat ttctgctaga ggtaatctta aatctccaac attgaatccc aataaattca
    34381 ttgcagtctt aactggtata ggatttactt ctataaataa agctgcgatt agagcatcca
    34441 taccaagttg taattttcta gaaccttcaa tatcgccttc aaagaattta gctaccaaat
    34501 cgtgagtttc ttgagggcaa acattagcaa gtactgatat aactccttga cctcctaaag
    34561 ataataaagg aagtatagta tcatcattac cagagtagat agcaaagtca tctggaacta
    34621 aactagctat ttctgcaacc tgtcctaggt ctccactagc ttcttttaca gcaactatgt
    34681 tatcaatttt agcaagttca actataaggc taggacttat atttacacaa gttcttccag
    34741 ggacattgta aagtataatt ggaagtttaa cactgttagc tattgtttca aaatgacgct
    34801 taagtccagc tttattagct ttattgtaat aaggtgttat tattaataga gcatctactc
    34861 ctaatttttc agcttcttga cttaagttaa ctgagtgcat agtatcatta gaaccacttc
    34921 cagctataac aggaactctt ttattaactt tttcaacaac atacttaata gtagcaagtt
    34981 gttcttcatc agtcatagta ttagcttcac cagtagtacc acaagatact atagcatcag
    35041 taccattagc tatttggtat tcaactaatt cacctaattt gtcaaaatca actttgttat
    35101 cctttgtaaa tggtgtaact agagcaacag cagaaccttt aaatatcata taaaatcaat
    35161 cccctctttt ttatttttgt gttttatatt acagttactt ctaatgcttg tttttgagtt
    35221 actattaata ttttacaaaa ttatatattt atacaagttt gtatattata ctaaatcgta
    35281 tgataaagcc atttcagcta tttgaattgc gttagttgca gcaccttttc ttatattatc
    35341 agcaacaacc caaagattta caccattatc aacactaaaa tctcttctta ttcttccaac
    35401 aaatacttca tctctatcat caaattctac agcagttgga tattcgtttt tagcaggatt
    35461 atcaactact acaacacctg gagcttcttc aagtgttttt actaaatcat ctaactcaaa
    35521 tggattgtta aactcaacat ttatagattc actatgacca ttttttactg gaactcttac
    35581 agtagttgca gttattttta aatcgtagtt atcaagtatt ttcatagttt catttaccat
    35641 tttcatttct tctttagtgt atccattttc agtgaatgaa tctatatgag gaagacagtt
    35701 gtaagagatt tgatgagggt agaatccagt aggattaccg ttcattcctt tctctaaatc
    35761 ttcaacacct ttaacaccag aaccagatac agcttggtaa gtagagtaaa caactctctt
    35821 aattttgtat ttatcatcaa gagctttaag gggaaccata gcttgtatag tagagcagtt
    35881 aggattagct attataccct tatgattttt tatggcttct ggattaacct caggaactac
    35941 taaaggcaca tctggattca ttctccattg actagagtta tctactacta agattccatt
    36001 tgaagcagct attggagcat acttttcact aatacttcca ccagcagaga ataatgctat
    36061 ttgtatgcct ctatcagtaa atgaagtttc ctttaattct tctactatat attctttacc
    36121 acaaaacatt actttagaac cagctgattt agaagaagag aataaaaata gattttctat
    36181 tggaaaattt ctttcttcta atacttttaa aaatgttcta cctaccattc cagtagcacc
    36241 aattattgct acatttactt ttttcatata aattcacccc aattttaaat tattaaaaca
    36301 ttattttatt ttagttatac aagtaagata tgttaatatt tttatatatc caaaaacttt
    36361 aatattatat taacaacttt aattatatac aaaaaacgta caaaggtata ctttgtacgt
    36421 ctaatttatc actcaaagta aaccctgtag ctcatcacct acaaaaataa gtgacagtat
    36481 tacacatgtt atgtgcaatc ccagaaaata ttattgcaag aaatattttc ttcggctgta
    36541 aatccttttt ccaatcatta acacctgcca gctactattg gatactctta gttacagcta
    36601 cctctaccct aggttaatag gatattaaaa tttgattatt ctaataataa tacatattta
    36661 agaaaaaatc aacttattta tataaatatt gctaaaattt aaatccaaaa tttgtcaatt
    36721 cttgttttaa cacattaaga ttagtttctt ccatttcagc tagaggaagt cttaaatcac
    36781 caacattaaa acctaaaatg ttcatggcag ttttaacagg aactggattt acttctataa
    36841 ataaagcagc aattaaagca tccatatcaa gttgtaattt ttttgagcct tcaatatcac
    36901 cttcaaagaa tttagttact aaatcatgtg tttctttagg acatatgtta gcaagtacag
    36961 agataatacc acttccacct aatgataata gtggtagtat agtatcatca ttaccggagt
    37021 atatagcaaa gtctttaggt actaatttag ctatttctgc aacttgagct aagtctccac
    37081 ttgcttcctt cacagcaact atattatcta ttttagcaag ttcagccaca acagatggct
    37141 ttatattcac tttagttctt cctggtacgt tgtataaaat aattggcaac ttaacgctat
    37201 ttgctattgt ttcaaagtga agtttaagac ctttctcatt agtcttatta tagtaaggag
    37261 ttattattaa aagaccatcc acccctaatt tttcagcttc ttgactcata tgaacagaca
    37321 acatagtatt gtttgaacca gtacctgcta taacaggtat tctcttatta actttttcaa
    37381 ctgtatattt tattacagca aaaatttcag attcactcat agtagtcgcc tcacctgttg
    37441 ttccacaaac aactagtgca tctgtgccat tctcaatgtg atattcgatt aattcaccta
    37501 atttttcaaa gttgacatta ttatcctctg taaatggggt aactaaagca acagcagaac
    37561 ctttaaataa catataatca aatctccttt tttatctaaa tttaattttt taagtacaat
    37621 aataattata gtacaaatta attaatttta ataggtatag ttaatatctt aactgtttaa
    37681 ataagatatt tatattatat taatattaga aaaattttaa ataaatgttt tattctcaaa
    37741 atatgcatat taatttaata aaatatacca aaatggaaat aaaaaataaa ttttatgaga
    37801 atttaataac taataattaa tatatttagg ttataataaa tatgtgcgta aaatctaaca
    37861 ataagcaata ataccgtaaa tttaggagga ataatatgga tactttaaag gaacttttta
    37921 aaataggaag tggaccttca agttctcata ctatgggacc acaaagagca gcagagagat
    37981 ttaagaatga aaacccagat gcagaaagtt ttagagcaat attatatggt agtttggcag
    38041 ctacagggaa aggtcactta actgactata taattgaaaa aactatagca cctaaaaaag
    38101 tcgaaattgt ttgggaagaa gatattataa aagattttca cccaaatggg atgaagtttg
    38161 aagctttaga taaagataaa aatgtaacag ctgaatggac tgtatattct gtaggtggag
    38221 gaactatagc agaagaaggt caaagaaaca gtaaaagcaa tagtatatat cacttagata
    38281 ctatggatga gatagtaaaa tggtgcaaag aaaataataa gactttggta gattttgtgt
    38341 tggaatgtga accaaaagac ataaaagatt atataaaaac tataaaagat gctatgagaa
    38401 aatctattga tgatggacta agtacagatg aaataatacc aggcaagtta ttattaaaaa
    38461 gaagagcaag tacattttat aatgcatata aaaaagataa gagcttctca acacttgtat
    38521 atgcatatgc actagcagct tcagagcaaa acgcttctgg taatataata gttacagcac
    38581 caacttgtgg ttctgctgga gtaataccag gaatattctt tgcaatgcag gatttctata
    38641 attatgatga cgaaaaaata attgaagcac tacttgtagc tggaataata ggtaatataa
    38701 taaaaactaa cgcttcaata tctggagcag aggtagggtg tcaaggtgaa gttggagccg
    38761 cttgttctat ggcagcagca gcagtagcat acttaaaagg tggaactata gaccatattg
    38821 aatatgcggc agaaatagca cttgaacatc atttaggaat gacttgtgac cctgtatatg
    38881 gatatgttca aattccatgt atagaaagaa atgcaatggc agctcaaaga gcttatgatg
    38941 cagctaatta tgcattatta actgatggct cacattctgt ctccttagac caagttgttg
    39001 aaacaatgaa agaaactggt atagatatga tggataagta caaagaaaca gctaagggtg
    39061 gacttgctaa acatttcttc tcttgctaaa aataaaattt tccaataata attcctctgt
    39121 tttgatttat gaaacagggg aattattatt aatggtgaat tatttaataa tgcaaaatat
    39181 ttttatattc aatttagctt tttattttta attagtataa catgctatat aatattttaa
    39241 ttataaagaa atatagaaat attttttaat aaattagaaa ttggaggaga ttacatgaga
    39301 gaggcatcat atttacaaga acaactttat aaacatagga agtcattaaa tcctattgca
    39361 gagattggga gaaaagagta taagacttca aaatatataa gagattatct tgataaatta
    39421 ggaattgagt atgaagttta tttagaaaca ggtatagtag gtgtaataga aggtaaaaga
    39481 cctaaaaaag atattgcttt tagagctgac atagatggtc ttcatagtga agaaggggta
    39541 aaacatttat gtggtcatga tggacatgct actatcttac ttggattaat tgagtattta
    39601 aatgataata aagaagactt aaatgataat atagtattta tattccaacc ggcagaagaa
    39661 ggtcctgggg gagcaaaagc tttaatagat gaaggagtgc ttagaaaata caatattgat
    39721 gaaatatatg ggcttcatat atatccagag ttaccagaag gttatgtagg tacaagagag
    39781 ggctatttta tggctcaaat aggagatatt gacatagaaa tagtgtctaa aagtggacat
    39841 ggggctatgc cacaaaatgg tattgatggt atagtgatag cttcaaactt tgtaagctca
    39901 cttcaaacta tagtgtctag aaatataagc ccaatagaca atgcagtgtt gactattggc
    39961 agaattgaag ggggagctag aagaaatata atagctgaaa atataaagat ggaaggtact
    40021 atgagatgtt tcagcccaga agtgtatgag aaaatgaagc ttagagttag agaacttgct
    40081 agagggtttg aattggctta taactgtaag gttaatataa atattataga tgattatatc
    40141 gctgttaaaa atgacaagga tttgtatcaa gagtttgtag aggctattgg aagtgatact
    40201 gttgtagagt tagagccact tatgatatca gaagattttt cttattatca aaaagaagtt
    40261 ccaggattat tttttatgtt gggttcaaga aacgaagaaa aaggatttgt aaatggtctt
    40321 cataatataa actttaattt tgatgaaaag atatgtgtaa atgcattgaa tgtttattca
    40381 aaattattaa aatacaaaga agcaatagat taggaagata agttataaag attaaaaagc
    40441 ataaatacct aaatttaaaa aaagtgtatt aataaatacc ccttacatat ttgtataaat
    40501 ttattttaat tgacaaaaat acaaataaga aggggtgatt tttttgaaag aaaaagtaca
    40561 aagagaaaag aagataacta atggcaagaa tactaaaata ttgacaaatg atgatataat
    40621 gaaatatgag atagcctcag aactaggtct tatggataaa gttggtgaac gtggatgggc
    40681 aggacttaca gctaaggaag caggaagaat tggaggtatg cttacatcac gcaaaaagag
    40741 gcttaaaaag attgtggagg agcagaataa aaaggatgag tcaatatagt gattttgcgt
    40801 ttgtatatga tgaacttatg aatgaagttg attataatgg ttgggttaaa tatatagaag
    40861 atataataga tagtgaaggt gtaaaagtaa aaaatatatt ggaattggca tgtggcacgg
    40921 gtaatcttac aattccattg actaaaaaaa attacgatat agctggtata gatatatctg
    40981 atgagatgct tagtgtagca agagaaaagt cagaaaaaga aggagtagaa ttagttttac
    41041 ttcaacaaga tatatcagag cttgattttg aaatatctga tttggactgt gtactttgtg
    41101 cttgtgatgg attcaattat ataacttatg atgatgattt ggaaaatgta ttttcaaaga
    41161 catatgaatt attaaagaaa gatggaatat tcatatttga tataagttct ttttataaat
    41221 tagccaacat attgggaaat aacatgtatg gagaaaatag agaagatata gcgtatatgt
    41281 ggcaaaatta ctttgatgaa gaagagaatc taattgaaat ggaacttaca ttctttatta
    41341 aagatgaatg tggaaaattt gaaagatttg aagagataca ccaacaaaga gcatatactg
    41401 aagatgagat agttgatatg cttgaaaaat ctggatttaa ggatataaaa tattatgggg
    41461 attttacatt tgacaaacct agtgaagaaa gtcaaagaat cttctttgta tgtaaaaaat
    41521 aagatatttt tgactatata agataattat taaaaataac catgatataa aaatatagaa
    41581 aatgcagttt tatagattaa aagtaaagtg atgatacttt atgactttta ttttttaata
    41641 attataaagt tctatagata aaaattaaaa tataataact attgcttagt aaaattaaaa
    41701 taaaatgggt tttgcccaag gttaagatag ataagtattt atagattaaa attaaggtag
    41761 taatataata aaaataagac aattaacggg acatggagga atattaatga gagattatgt
    41821 actaagagcg acatcaggaa atggtcaagt tagagcattt gtcgcaacta ctagaaatac
    41881 agtagaagaa gctagaagat tacatgaaac tacaaaagta gcaacagcag cacttggaag
    41941 aacattaaca gccacatcta taatgggatt aatgatgaaa aatgatagtg ataaattgac
    42001 tgtaataata aaaggtggag gtccaattgg aactattatc gccacatcag actctaaggg
    42061 aatggtaaaa ggatatgtag gaaatccaca agtagaggtt gaagactatc caaatggaaa
    42121 gttaaatgta gcagcagcag taggtacaga aggtgttgta aaagttataa aagacttagg
    42181 tcttagagaa ccatataatg ggacttatcc attggtaagt ggagaaattg cagaagactt
    42241 tacttattat tttgctgtat cagagcagac tccatcagta gtagctttag gtgttcttac
    42301 aaaagaagat gaagtagagt ttgctggagg atttatagtt caattaatgc cagatgcaga
    42361 agaagagact attgctaagt tagaggaaaa tgtagctaaa ttaccttcta taactaacat
    42421 gttaaaagaa ggaaaatcac cagaggatat attaaatatt gttttggatg gtttggaacc
    42481 taaaatactt gatacctgtg aagttgggtt tatgtgtgaa tgttcaaaag aaagagtaaa
    42541 aactgctttg gttgcaattg gtaaaaaatc attggctcaa ataatagaag aagataaaaa
    42601 agcagaagtt ggttgccagt tctgtaataa gaaatatatg tatagtgaag aagagttgct
    42661 tgaaatttta aaggaaatgt agactataaa aatagttgta ttgatataag taatgttata
    42721 gtgatatagt aaagtcgtat tgatatagta attaaagtat aatttattaa taatagacat
    42781 atttatatta aaaaataagt ttaataaatt tttaagctta ataaatttta agaattaaga
    42841 agctttctgg ctgtaatgtt tgcaatgttg cagttagaag gcttttttat tttattatag
    42901 ttcgtgtcaa agattgtatg aaacaataaa atattgtaaa ataatttgta tatttagacc
    42961 tgattggcac aaaggtttat aaggtatttg agttgattat gcgaaattct atgaagtagt
    43021 aaccctgtga ctttaatcat gggaggttca gaagaaggag aaaattttaa atatggaaag
    43081 taaaacgaag tacataggaa taagtatatt aatattattg atgatatttt taattgcaaa
    43141 aaattttaac ggaaaacttg aaatacctat tcctgagagt aatagtagaa aatttaaatc
    43201 agcagcagtg ttttatcctc aacatcaaga tgatgaggtt ttatggggag gaagtgccat
    43261 tgtagatgct ataaaacagt gtggtgttga taatgtatat gtggtattag tatcagatgg
    43321 ttctggagtt aacgttttca aagctaacac aaaatttaga aatttaacta ggaagcaaaa
    43381 ggaagaactt agaaataacg agtttaaatc agctttgaga gagcttggag tgaaacctca
    43441 aaatgtgatt atacttgcag atatagataa aaaggaaggc acacattatg aattaatgga
    43501 aaagactata ttggattttg aacataagtt taaaggcaat gtgacccata tagcccatca
    43561 ctataagtat gatgaccata taatgcatag aaagaatggg gaagttttaa agaaacttaa
    43621 acgtgaaggt aagataaaag atgacttgta ttttgttaag ccaaaatatg taaagtatat
    43681 accaagaaat gaaagagcta tctataaagc aatggatttt gatgactaca ataaggttaa
    43741 gagtgcttgt tatgaatata aggttgtaaa ttcaaagcgt aaaatgtatg gtataggata
    43801 tatttcggca catagttatt ttgaacatct tctaaatgac cctgaactta cgtctgtatt
    43861 aagtgaagat taatttctta taagtagtaa gttatgtttg ataagttgat tggaattttc
    43921 tatagttttg aaggtattgg aaatttagtt ttatttaaag atttaaagat agaggttttt
    43981 agtgtttaaa attttaaagt taagttgaat aattgtatag aattatttgt gaaagaagaa
    44041 acagtgtaaa acatagtatc ttatttatgg ttttaaaatc ataggcaaga tacttttttt
    44101 atgtaactaa taccattttg agattattaa cttaagaatt ttatataatt taacactcat
    44161 atataatgat gatatttagg tagaatagat gcaattacgc ttaaataaaa taactgtatt
    44221 ttttataaaa atcaaaccct acactatact accagataaa atctacatgc tataatttga
    44281 cctgtgttta taaaaaaagg agtaatctaa taaaatagta tttcacttat gtataactaa
    44341 caactattat tacgattttc tctaaataat ttaaagaaaa ataatgcagg aggtaaaata
    44401 tgaacaatga atttataatt ttaaaaggtt gcaaagagaa caatttgaac aatatttcct
    44461 taaaaatacc aaaaagaaaa ataaccatat tcacaggggt gtcgggttct ggaaagtcat
    44521 ctattgtatt tgagacaatt gcaaaagaat cacaacgcca actaaatgaa aggtttagta
    44581 catttgtaag aagtttttta cctaagtatg gagaggttaa agctgattgt atagaaaatt
    44641 tgtcaacacc aattatcata gaccaaagta gacttggtgg aaattcaagg tcaaccctag
    44701 gtactattac agatgtaaat tcctttttaa gagctttata ttcaaggttt ggtagtgagt
    44761 atataggtaa tgctaatatg ttttctttta ataatattga tggtatgtgc ccacactgtc
    44821 atgggcttgg aaaaaagcta gttcctaata tgaaccaaat tcttgatatg aataaatcat
    44881 taaatgaagg tgctatattg ctttcagggt ttggagtggg ttcttggcat tggaatatat
    44941 tcgctgaatc aggatttttt gatattaata agaggatatg tgattattca gaagtagaat
    45001 tggaaaagtt tttgcatggt aaagcagaaa agattaagat agaaaatgct ggtcaaacta
    45061 acatgacata tgagggatta atggttaaat ttaatcgcct atacttaagt agagagggag
    45121 aaatatctga agctactaag aaaaaattga gtaaacttct tatagaagat agatgtccta
    45181 tatgtgatgg aagaagactt aatgaaagag tatataggtc tttaattaat ggttataata
    45241 tagcagattt aactagtatg caaattgatg aattggctga agttattaaa agtatagatg
    45301 agccagaagc acaaccttta attaaaggaa taatagaaaa gttaaacagt atcatagata
    45361 taggtcttgg atatttaaca ctggatagag agacatcttc tctatcagga ggggaatctc
    45421 agcgtataaa gatggttaag tatttaaata gtaatcttgt tgatttaatg tatatttttg
    45481 atgaaccaag tgtaggactt catccaaaag atgtgtataa attaaataat cttttaaaaa
    45541 aattgcgtga taaagggaat acaattatag ttgttgaaca tgacccagat gttattaaga
    45601 ttgcagacca tattgtagat gtaggaccaa aggcaggtaa gtatggtgga gaagttgtgt
    45661 atgaaggcag ttatgaaaat ctacttacaa gtggtacttt gacagggaat gctttaagta
    45721 aatttcttcc tattaaagaa agtgtaagag aacatagtgg atatttagaa gttaaaaatt
    45781 gtaataaaaa caatttaaaa aatgtatcga ttaagatacc taaaggtgta ttgactctag
    45841 ttactggagt agcaggagca ggtaaaagta cgttgattaa ggatgaattt ttaaagcaaa
    45901 atcctagtgc tgtacttata gaccaaagcc ctgtttcagc aaattcaagg tcgagtttgg
    45961 caacatatag tggaattatg aacaacataa gaagcatatt ttcaaaaaca aatggcgtaa
    46021 atgcttcttt attcagttca aattcagaag gagcttgtga taactgtaag ggttctggaa
    46081 tagtagaaat gaatcttgct tttatggaga gtataaagag tacctgcaat gtttgtgaag
    46141 gtaaaaaatt taaaaaagaa gttttagaat ataggtttca agggaagaat ataattgaag
    46201 ttcttgaaat gtctgtttta gaggcaattg agttttttaa tttaaaacag attaaaacga
    46261 aattacaatg tattgaaaaa atgggtattg gataccttac tttaggacaa actcttgata
    46321 ctttgtctgg aggagagtgt caaagattaa agcttgctag tgaattaaat aaggaaagtt
    46381 cagtgtatat attagatgaa ccaacaacag gtcttcatat ggctgatatt gagaatttta
    46441 taagtataat tgaagagatt gtagataatg gaaatacggt cataataatt gaacacaata
    46501 tagatgtaat taaaagagct gattggatta ttgagctggg acctgaagga ggaacaaaag
    46561 gcgggagagt aatatttgaa ggtattccaa aacaattatg taacaataaa atatcattaa
    46621 cagcaaaata tatagtataa taaataaaat ataataaaat tataatgata ttttaataaa
    46681 tataatgggt atataaaatg ataattaaac ttaacagtaa taaataatgt gagaaatatt
    46741 caaatttaat taaataaagt gtcagaaatt tgtttaaatt ttagtatttt aacggttctg
    46801 accttttttc ttatttttat ggagaatatc gaggatggag tctctaatag ttactttttt
    46861 gtgtctactt gcaagtttga ttaaaaaatg gctatacaca cttgtgactt cagtcatggg
    46921 aggttcagat tataatctta atatataatt tgtgaaataa tttgatgacg atttgctgat
    46981 gtataaacaa taaagattaa ctacattaaa atttaaatct tgttaagtaa aacttataaa
    47041 aggagagaga tggatgataa atgatattct aaccttatta tctgaaagaa gtgatttttt
    47101 tataaagcta tccatagaac atttgatgat ttctattatt tctataataa ttgcgattgt
    47161 tttgggtggt ataattggta ttattgtaag tgaatttcat aattcttcta aacctatatt
    47221 gggaactatc aattttctat acaccattcc atctatttct atgctaggat ttctgatacc
    47281 attttccgga attggaaata ctactgctgt tattgcactt accatttatg cattattgcc
    47341 aatggttaga aatacatata ctggaattac taatgtggat aaaaatattc ttgaagcagc
    47401 taggggaatg ggaagtacag attttcagat attgtataaa ataaaacttc cgttagccct
    47461 acctgttatt atgtctggta ttagaaatat ggtgattatg acaattgcat tagctggtat
    47521 cgcttcattt ataggtgctg gaggtctagg tgtagccata tatagaggaa tcacgacaaa
    47581 taacacaata atgacaatta ctggaagtat acttattgct ctattagctt taatatttga
    47641 ttttatttta gggctggtag aaaaattttt tcaacgaaaa agaaaaaaga aaaataggaa
    47701 aaaagttttt gccattctag gaagccttat tcttatagca actatcttta cgtcttattt
    47761 atttaatcct tcaaagactc aaactattca tattgctact aaacctatga ctgaacaata
    47821 tattcttggt gagatgttgg atattttaat tgaaaaaaac acaggtctaa acgtggaaat
    47881 tacacaaggt gtaggagggg gaacatctaa tatccagcca gctatggaga atggagaatt
    47941 tgacatttat ccagagtata caggtacagg ctggaatatg gtacttaaga aaaatgaatt
    48001 atatactgaa agtatgttta gtaaactaca gtcggaatac aaaactaaac ttaaaatgca
    48061 atggactggt atgtatggtt tttctaatag ctatgcatta gcagttagaa aagaagttgc
    48121 agataaatac aatttaaaaa atataacgga cttaaaagat gtatcttcta aattgacatt
    48181 tggagctgaa tatgactttt atgagagaga ggatggatat actccattgt gtaatacata
    48241 tggactgaac tttaaagata cagttgattt agatattgga ttaaaatacc aagctatcaa
    48301 tgaaggtaag attgacgtaa tgcctatatt tacaactgat ggtcagtata gtgtttcaga
    48361 tgttgtagtt ctaaaagatg ataaaaattt ctacccatct tatcaatgtg gaaatgttgt
    48421 tcgtttggaa gtattagagg aaaatccaga actatcaaag gtatttaaga tggttggaga
    48481 tattttgact gataaagaaa tggctaaaat gaattatgac gtagaaaaca acaatttaga
    48541 acctagagaa gttgctcgtg agtttctgaa taagaaaggt cttttataaa ttggaggaaa
    48601 tataatgaca cctattatac aatttaaaaa tattaaaaaa caatataatg ataaaactat
    48661 aatagataat cttaatttag atatagaaaa aggagagttt ttgactgtaa ttggttcgtc
    48721 tggttctggt aagacaacac tcttaaaaat gattaatggt ctgattttgc cagatggagg
    48781 aaatattttg ataaaccaaa cagatatcaa aaacgaggac ttaattaaat taagaagaag
    48841 aataggatat tgtgtacagg gaagtgttct ttttcctcat atgactgttg aagaaaatat
    48901 ttcatatgta ccaaatctcc taagtaaaaa gaataaatta gaagtaaaaa gtgctgtaaa
    48961 caagtggatg gaaatagtgg gattgccaaa tgatatgaaa gtgcgttacc catcagaatt
    49021 gtcaggtggt cagcaacaac gtgtagggat tgcaagagct ttagcttctt ctccagaaat
    49081 tttattaatg gatgaacctt ttggtgcagt tgatgagatt acacgaaagc aattacaaaa
    49141 agagataaaa gaaattcata aaaaaacagg agttacaatt atctttatta cgcatgatat
    49201 ttatgaagct ttgattttgg gaacaaagac tttggtatta aatcatggag ttgttcaaca
    49261 gtatgatact cctgagaata ttttaaatac tcctgctaac caatttgtag accagttatt
    49321 gaatataaga aaatctataa tagatgatga taatttaaaa gaataaattt aaatttaaaa
    49381 tcaaattgtt gtgataaaaa ctattgattt agagctaact tcaagttgta tacttgaagt
    49441 ggaaaagtta gattaaggta tagaagggca tttagcagtt ggctgtagac gaggtaactg
    49501 ctgaaggtgc tttcaataaa tggctagaac ctgtatctgt tgaagattat aataaattga
    49561 aataagaagc tcaatataca gagtagatag gcacttcaaa tagaagtgtc ttttgtgtgc
    49621 cataaaataa atcaaaatat tagcaaagaa tgtgaaaaac aaaataaaat aatatgctat
    49681 ctttaaaata ggagggatgc tatatggata acaatttgat taccattgaa aaaactttag
    49741 attatataga aaaacatctt ttagatgaga tgttagattt aaatgtaatt tctaaagaga
    49801 taggctattc aaaataccat ttacatagaa tgtttacatc agttgtcgga tttagtgtac
    49861 ataattatat acaaagacgt agacttactg aagtagcgag aatgctaatt tttacagaaa
    49921 aaccaattat tgagattgct ttaatctcgg ggtatgatac acaacgctct ttttcaagag
    49981 ggtttaaaaa aatgtttaaa cgtagtccta atttttttag aagacatcaa gattttttac
    50041 cactacaatt aaaatttgat attcataata gaaaaaaatt acgtggagat atggttttag
    50101 atgttaaaaa agttaattgt gcagatataa atattgttgg ctattctggt aaagtaagaa
    50161 aaggatttca tattattgga aaatgctgga gggatttgca taaaaataaa gagatgatag
    50221 aaaataaggt agatttaggt tttttaattg gagttagtga ttatagcaat tttaaagaga
    50281 ttgagaatac tcctacattt acatacattg caggtgctca agtagctact tttggcaaat
    50341 tacctaatgg aatggaaaaa ttcgtattac cgaaaagtaa ttatattgtt tttactttta
    50401 ttgggaaaaa tgaggatagt atgcaaaatg ttgtagaata tatctatcaa gaatggttcc
    50461 ctaattcaag ttgccagttt aatgaaaata atttatatga ctttgtaaaa tatggagaaa
    50521 aaactgatga gaatggtttg agtgaaattc agttttgggt tccaatcatt taaaagaagg
    50581 tattatgtat aaagtagatg gatttatata ggcaaagttt tacagcagta tgtatttata
    50641 aataatttat agtttgtagg aaagaaataa ttttactata agattatgat aaaatacaca
    50701 atactatgac aaaatagtgt taaataatag atttaatttt gcataggaaa agttctataa
    50761 tggtgtgtat tcataaataa tttataatct gtaggaaaga aatagtttta ctataagatt
    50821 atgataaaat acacaatact atgataaaat agtactaaat aatagattta attttgcaaa
    50881 ggataaggtg ttttaataaa aatgaatgta gaaaacgaat tacttaaaaa cctagataga
    50941 ttgcatacaa cagagttagg cgttgtaaga attaagaaaa atctttcttt ggagacaaat
    51001 gatgtagtga actggtgtaa aactaaaata gaatctccaa atgccattat taatagaaag
    51061 ggaaaaaact ggtatataag tgtatatgat tgtattataa cagtaaacgc tcacagttat
    51121 acaattatta cagctcataa agaaaagaaa tgaattgcaa aatacaaagg tcaaaagcat
    51181 tttccactgt ttgtagtacc tatgaagaag tatataaaat aatattactt ttgaataata
    51241 atttaaattt tggaggttga aaaaatgaat gatactgtaa aagaaaaatt ggcagagtca
    51301 ctaacttctg atactactga tattttacct tatttgcctt atttattaca agatttttgg
    51361 gaattaggaa gttcaccaga acaaatgtta caattattta gaaagcatat accttttaat
    51421 gaggatacaa aagttttgga tttagcttgt ggaaaaggtg ctgtatctgt gaagcttgca
    51481 aaagagttga atatacatat caaaggtatt gatttgatac ctgaatttat tgattatgct
    51541 agaagaaagg ctattgaata taaggttgat gctttgtgtg attttgaaat gaatgatgct
    51601 aatagttctg taaaaattga gcatgattat gattgtgtga tttttggagc tgtaggggat
    51661 attttaggta attataaaga aactataagt aagctattac ctacaataaa aagtaagggg
    51721 ttcattttaa ttgatgatgc atatgtagta gataaatcta caaatgaaca gcttaatttt
    51781 gagagggtgt atcccactta caatgagtgg tgtatattgt tcaaagaatt aggtctgaag
    51841 ctaattgaat gtataccatg tttagaactt gaaaatgatg ttgaagagga aatgaattgg
    51901 attataactc gtgcaaatga gctaattaaa aaatatcctt ctcaaaaaga tatgtttgaa
    51961 caatatgtta ttagccaaaa aaatgaatat actgatttac agcaggacct tgttggagca
    52021 acttggattt tacaaaaaga ataagataaa tattagacta gataatcaat gttatagtga
    52081 attatcccat gtctagtgaa tataaataac ataaaaaacc gtcaagatga atagtttatt
    52141 cgtgcttgac ggtttttagt atttgttgaa gtaaaatttt atttctttag tatatcactt
    52201 ttagtcaatc catttgattt agcttgagta ttccattgat gattccccat aagtttatat
    52261 aggaatctag ggaagttagg tgaaataaaa atagtacttt tgttggaatc atctatatgt
    52321 atattatcac taagtatatt ttttgaaagt tcttttaatg caattcctaa atctttttta
    52381 ggtcctttac ccaaaggtac ggattctagt gaaccaaaca tctccccagc tccaattcca
    52441 ataccttgaa cccatgtaaa gttgattttt ttacaccaat gctctatcat ttgaattgcc
    52501 aaatgattat gttcaccttc attgaatcca cagttaacta ttgcatacac tggaataggt
    52561 tttttatttt gtgtttttaa aaatttttca catttctcta aaaaatgaag taaatgagat
    52621 ggaataccat ctacataaag aggagatgcg attattaatc tatcacaatt aagtatggca
    52681 ttaagagcgt caggatactt agatgtgtta tctactttaa atgtaaaaac tttattatca
    52741 ttttgaataa gttgttttaa ttcagataaa aaatactgtg aattattttt atttactttt
    52801 ggactaccat ttatcattac tatattcata tggattcacc tcttatatct tgtatatttt
    52861 catagaaaca aacagagtgt tcttttatat tgaaatttat agcatttcca tttactaatt
    52921 tcgtagcagt ttctttttca gcttctgtaa tacaatctcc atagaatata gcttttaaat
    52981 ttatctgttt atcatatctg cttttatgac gcatcatatt atcttttatt acaaagtatg
    53041 gaagaatata attaatgctt ttatcaagta cgtttttgac aaaagggcta aaccctccgt
    53101 aacagcatct gcttattata ataattccat cagagtcatt tataagttta cccatgttgc
    53161 tgtaataatc ttttacaaca cattcagaag gagttttaat ccagcaacca aaacaaccaa
    53221 tacatttgtg gatttctttt gtgtttggaa gtatttttat attgtcatca agtttgggta
    53281 ataacttttc taattctttg tcagttaaat catgtattaa aagcctcata aagtccatct
    53341 ccttttatta tgtatgttta cttctaaaaa ttatatctta tagatttttc agtaaatctt
    53401 tacaccaatt aataacaaaa ttataatagt caactccata aatcattgtt gcatacatat
    53461 atgtatattg gtcaacacaa tgattttctt ctgcatcatt tttttgttta cttaatttat
    53521 ttagaagtaa ttctacttca gttattaaca tttttaagtt tgtttcaatt atttctttgg
    53581 gtagatactt gtaaaagaat atattaacaa ggtggtcttg ctttgtttta gaaaaattta
    53641 taggtttctt taaccattca agaaatactt ctttaccagt attagttatg gaatatagtt
    53701 tttttaattt gttaccatct ataacttcgt gatagtgtat atatcctttt gtttctaatc
    53761 ttttaagtgc aggatagata cttccaaagc tggcgtcaaa aaagtacgag gtactttctg
    53821 acattatttg ttttaagtcg tatccactta attctttttc cattaaaaat cctaaaataa
    53881 tgtattctaa catattacct cctggtatca attagatata tatcgattcg atatatttat
    53941 tattacagat aataaatctt acgtcaagat gctttttaag ataagctaaa aagaattagg
    54001 agttattgat aaatatgcaa aaaaattaat ataaaaggta attaaatatc aataaagatt
    54061 taaaaatagt taaatcaaag taagagtcta atatataaaa tttatagtaa ctttatggtt
    54121 taaatataaa cttgtgtgct attgacaaag tataaaatta gcagtagaat aattgcatga
    54181 gcaaatagat tgttgcgaac gcaaaaaaag gacaatagat attaaaggag agaatatgag
    54241 agagctatta aaatgggttt ccattataaa tagatacaat acaaattata ttgacaggaa
    54301 attggcggat attggaatca ataatagcca atatttttat gtattacaca tatgtaataa
    54361 tccaggtatt acacaggaca ctatatttga gaaaattctt gtgaatccta gtaatataac
    54421 aagagctttg gcaaatttag aaaaagaagg ctttataaca agagaaccag gtgtaaagga
    54481 taaaagaaca tggcatttat atcctacaga aaaatcttta ggatgttatg atgaaatact
    54541 aaaaataaca aatgggtatg ttgaggagtt gttgagttca tttgagaaag aagagcaaga
    54601 gttgtttatg tcaatgttaa agaaagttgc atttttggct attgatatga atgaagaagc
    54661 aaaattggag gcgaaggaaa atggaagaaa aatataagga gccattggaa tatgaaaagg
    54721 tttcaaagtt attaactaag tacgcaattc ctagtattat agcaatgtta gtaagtgctt
    54781 tatataacat tgttgaccaa atatttattg ggcaaggtgt tggtgtattg ggcaatgctg
    54841 ctacaaatgt cacttttcca ctaacaacaa tatgtactgc aattgcatta ttgttaggaa
    54901 ttggaggagc gtctaagtgt tcattggaat taggtgctaa aaattcagaa aaagctacaa
    54961 aagcagcagg aaattctata tgcttgatgg ctgtttttgg aataagttta tttatagtag
    55021 tatcaatatt tttaacacca ctattaaaat tctttggctc tacatcagaa atactacctt
    55081 atgcacacac atatacaaaa attacatcaa ttggattacc atttcttata atgtccactg
    55141 gaatgagtaa gttgatactt gcagatggga gaccgaaagc ttctatgttt tgtatgttaa
    55201 taggagcagt tattaataca attttgaatc cattattcat ttttgttttt aatatgggaa
    55261 ttgctgggtc tgctttagca actgttattg ggcaacttat atcttttgga ataagtgttc
    55321 attatataaa gaattttcaa catattaaat tacataagaa aagttttaaa ttagatagta
    55381 taatttataa acatatattt gcgctaggtt caagctcatg ttttaatcaa ttagcaatga
    55441 ctgtaacaca gatagttatg aataatacat tggcatatta tggggctagg tcagtttatg
    55501 gaagtgagat tccacttgct tgtgtcggta tcattattaa agtaaatatg atttttatat
    55561 ctataattat tggtatatca caaggtatgc aaccaattat agggtataat tatggggctg
    55621 aaaagtataa tcgtgtaaaa gaagcatata agtttgcagt gggaagtgca actattatat
    55681 ctgttattgc attcttatgt ttccaattat tcccaagaca aattacgtct atatttggta
    55741 acggaaatga gacttatttt atatttgcag aacattattt tagaactttc ttgttcttaa
    55801 catttataaa tggtgttcaa atagtatcat caactttctt tacatcaatt gggaaatcag
    55861 tgttgggact ttttacttct ttgactcgtc aaattttatt tttaattcca ttgatagtaa
    55921 ttttaccaat gtttatggga attgatggag taatgtttgc aggaccaata gcagatgcag
    55981 cagcggcaat ggtatgtata tactttgcag ttcatgaaat gaaatcattg actataaagc
    56041 aaaataattt gatgagtaac cataataaga ttgcagaggt ataagacaat atttaagaag
    56101 tatagaaaat taatttaaag aagtataata aactaattta ggaagtatag aaaattaatc
    56161 taaagaagta taataaacta atttagaaag tatagaaaat taatctaaag aagtgtaata
    56221 aactaattta ggaagtatag aaaattaatc taaagaagtg taataaacta atttaggaag
    56281 tatagaaaat taatttaaag aagtataata aactaattta ggaagtatag aaaattaatt
    56341 taaagaagta taataaacta attcaggaag tatagaaagc taatctaaag aagtatagta
    56401 aactaattta ggaagtatag aaaattaatc taaagaagta taataaacta atttaagaaa
    56461 tatagaaaat taatttaaag aaatacaata cattaatttt taagtaacat taaattaatg
    56521 taagtaaaat aatgttcata tgaagattta aaggtgcatt ttctgaagct aagtatatgt
    56581 tgtagagtgt taggtctctc tatcctgtga agtttaatag ctcaagaaaa tgcactattt
    56641 atgatgatta ttttgtttta tttccaattt tggaaataac tattctaatt aaatctaaaa
    56701 ttataccata aataagaaaa gaaagtatag atgctatgta ccaataaatc gaaattgacc
    56761 ctgtaattgt tctacatggg atttgcatac ctgaatccat aaaaacaaaa aaactatcaa
    56821 ctctggaaat aatagacaaa ataggattta aacctattag aacaatactt tttgagtctt
    56881 gaccaatttg atgcatataa atctcaaata atgcaattaa aaaaaaccaa aatgtaaaag
    56941 atttaataat ttttttcatc aaaatacctc acataatata aattctgttt gcactatttg
    57001 cttactacaa ctatttatct ccattcagtc acatcactta attgtaatct aggtcttctt
    57061 gatggttctt catcaggata acccaaagat attgctgcca ctaattgact atctgtattt
    57121 aaccattcac ataattcacg atatgcaaag tatacatcac aaatccaaag actacctaga
    57181 cctaattcca cagctgtaag cgacatattc tgaattgcag ctccaattga ttgcatgttt
    57241 gccatttcat agaatcgttc ttcaggggat agcttttcta aaggtgattt acctaatata
    57301 tttaaaataa aaattgttac tggagcttgt ttcatgattt caactgtgta atttgcacca
    57361 gcgatatgtt gacgacttcc tggaagaagc ccattatcat taatttcatt ttgaatacct
    57421 ttgctcatgg ctttaagcat agattctttt tccttttcag tgatgacaac aaaacgccat
    57481 ggttgcctgt ttttagatga aggtgcattt attccagctt caattatttt ctctatagtt
    57541 tcatgtgaaa tgctttgatt tttatatttt ctgatacttc gtctttttga tatagaatca
    57601 cttatcattt taagtaacct ccgtttattt tttggaaaaa tctatttaat ttttattttc
    57661 tattttaatt attttagcat taatcagaaa aaaagtcatt gattttagta tacaattatt
    57721 aatgattata ttaagaattg tatcaaaaag tatgtgatta tactaaggga ttatattaaa
    57781 cattatattt aaaattgtat gaaaggttgt atttaatatt atattgagag atatatatat
    57841 taggatttat atatattcag atttattatt atattgagcc ttatattaaa ttaaggacta
    57901 taatttgaaa ataagctata aaaacttaat attgttttgt tcagagataa aaaaagaata
    57961 ctttaggtga tttttattaa aaattaagag tgataaaatt atatacttta taaatgtaaa
    58021 tatgacgaat aaa
//
LOCUS       DAGQVA010000016        57190 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.016, whole genome shotgun sequence.
ACCESSION   DAGQVA010000016 DAGQVA010000000
VERSION     DAGQVA010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57190
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.016"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..656
                     /locus_tag="MIV85_001146"
     CDS             <1..656
                     /locus_tag="MIV85_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2960512.1"
                     /translation="VSIIGSNGTGKSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRR
                     TQIVSRVFQDPSLGTCPSMTVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLD
                     LKKYLDVQVKFLSGGQRQSLSLIMSCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIV
                     REKNITTLMVTHNLKHALHYGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            787..1809
                     /locus_tag="MIV85_001147"
     CDS             787..1809
                     /locus_tag="MIV85_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2960513.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(1972..2529)
                     /locus_tag="MIV85_001148"
     CDS             complement(1972..2529)
                     /locus_tag="MIV85_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBY2960514.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPIKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2535..3611)
                     /locus_tag="MIV85_001149"
     CDS             complement(2535..3611)
                     /locus_tag="MIV85_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBY2960515.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3612..4295)
                     /gene="modB"
                     /locus_tag="MIV85_001150"
     CDS             complement(3612..4295)
                     /gene="modB"
                     /locus_tag="MIV85_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBY2960516.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4444..5256)
                     /gene="modA"
                     /locus_tag="MIV85_001151"
     CDS             complement(4444..5256)
                     /gene="modA"
                     /locus_tag="MIV85_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2960517.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDNGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5449..6378
                     /locus_tag="MIV85_001152"
     CDS             5449..6378
                     /locus_tag="MIV85_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960518.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6539..6988)
                     /locus_tag="MIV85_001153"
     CDS             complement(6539..6988)
                     /locus_tag="MIV85_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960519.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7191..8171)
                     /locus_tag="MIV85_001154"
     CDS             complement(7191..8171)
                     /locus_tag="MIV85_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2960520.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            complement(8376..9236)
                     /locus_tag="MIV85_001155"
     CDS             complement(8376..9236)
                     /locus_tag="MIV85_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBY2960521.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(9553..10881)
                     /locus_tag="MIV85_001156"
     CDS             complement(9553..10881)
                     /locus_tag="MIV85_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBY2960522.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(11029..11358)
                     /locus_tag="MIV85_001157"
     CDS             complement(11029..11358)
                     /locus_tag="MIV85_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBY2960523.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(11382..12671)
                     /locus_tag="MIV85_001158"
     CDS             complement(11382..12671)
                     /locus_tag="MIV85_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2960524.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(12687..13013)
                     /locus_tag="MIV85_001159"
     CDS             complement(12687..13013)
                     /locus_tag="MIV85_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2960525.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(13148..13777)
                     /locus_tag="MIV85_001160"
     CDS             complement(13148..13777)
                     /locus_tag="MIV85_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960526.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(13993..16650)
                     /locus_tag="MIV85_001161"
     CDS             complement(13993..16650)
                     /locus_tag="MIV85_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2960527.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKHYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(17009..17953)
                     /locus_tag="MIV85_001162"
     CDS             complement(17009..17953)
                     /locus_tag="MIV85_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960528.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(17946..18971)
                     /locus_tag="MIV85_001163"
     CDS             complement(17946..18971)
                     /locus_tag="MIV85_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960529.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(19046..20614)
                     /locus_tag="MIV85_001164"
     CDS             complement(19046..20614)
                     /locus_tag="MIV85_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2960530.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGVFWNIADWTIE"
     gene            complement(20727..21638)
                     /locus_tag="MIV85_001165"
     CDS             complement(20727..21638)
                     /locus_tag="MIV85_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960531.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(21622..22608)
                     /locus_tag="MIV85_001166"
     CDS             complement(21622..22608)
                     /locus_tag="MIV85_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960532.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            22968..23369
                     /locus_tag="MIV85_001167"
     CDS             22968..23369
                     /locus_tag="MIV85_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBY2960533.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23372..23770
                     /locus_tag="MIV85_001168"
     CDS             23372..23770
                     /locus_tag="MIV85_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBY2960534.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(24220..24444)
                     /locus_tag="MIV85_001169"
     CDS             complement(24220..24444)
                     /locus_tag="MIV85_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBY2960535.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(24479..25846)
                     /locus_tag="MIV85_001170"
     CDS             complement(24479..25846)
                     /locus_tag="MIV85_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2960536.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTAMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(25930..27465)
                     /locus_tag="MIV85_001171"
     CDS             complement(25930..27465)
                     /locus_tag="MIV85_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960537.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDAILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(27488..27922)
                     /locus_tag="MIV85_001172"
     CDS             complement(27488..27922)
                     /locus_tag="MIV85_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960538.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(28182..29093)
                     /locus_tag="MIV85_001173"
     CDS             complement(28182..29093)
                     /locus_tag="MIV85_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBY2960539.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            29389..29742
                     /locus_tag="MIV85_001174"
     CDS             29389..29742
                     /locus_tag="MIV85_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBY2960540.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(29961..30902)
                     /locus_tag="MIV85_001175"
     CDS             complement(29961..30902)
                     /locus_tag="MIV85_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBY2960541.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(31003..32238)
                     /locus_tag="MIV85_001176"
     CDS             complement(31003..32238)
                     /locus_tag="MIV85_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBY2960542.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSQSKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLI"
     gene            complement(32282..33136)
                     /locus_tag="MIV85_001177"
     CDS             complement(32282..33136)
                     /locus_tag="MIV85_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960543.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(33264..34439)
                     /locus_tag="MIV85_001178"
     CDS             complement(33264..34439)
                     /locus_tag="MIV85_001178"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBY2960544.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(34538..35422)
                     /locus_tag="MIV85_001179"
     CDS             complement(34538..35422)
                     /locus_tag="MIV85_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBY2960545.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            complement(35654..36340)
                     /locus_tag="MIV85_001180"
     CDS             complement(35654..36340)
                     /locus_tag="MIV85_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBY2960546.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            complement(36368..36679)
                     /locus_tag="MIV85_001181"
     CDS             complement(36368..36679)
                     /locus_tag="MIV85_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBY2960547.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            complement(36868..37389)
                     /locus_tag="MIV85_001182"
     CDS             complement(36868..37389)
                     /locus_tag="MIV85_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2960548.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            complement(37486..37980)
                     /locus_tag="MIV85_001183"
     CDS             complement(37486..37980)
                     /locus_tag="MIV85_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2960549.1"
                     /translation="MIRKANMNDLESIMQIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            complement(38014..38487)
                     /locus_tag="MIV85_001184"
     CDS             complement(38014..38487)
                     /locus_tag="MIV85_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2960550.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            complement(38813..39808)
                     /locus_tag="MIV85_001185"
     CDS             complement(38813..39808)
                     /locus_tag="MIV85_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBY2960551.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            complement(39830..41755)
                     /locus_tag="MIV85_001186"
     CDS             complement(39830..41755)
                     /locus_tag="MIV85_001186"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBY2960552.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            complement(41780..42973)
                     /gene="nifV"
                     /locus_tag="MIV85_001187"
     CDS             complement(41780..42973)
                     /gene="nifV"
                     /locus_tag="MIV85_001187"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBY2960553.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            43435..44544
                     /locus_tag="MIV85_001188"
     CDS             43435..44544
                     /locus_tag="MIV85_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBY2960554.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            complement(44921..46105)
                     /locus_tag="MIV85_001189"
     CDS             complement(44921..46105)
                     /locus_tag="MIV85_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960555.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(46707..47522)
                     /locus_tag="MIV85_001190"
     CDS             complement(46707..47522)
                     /locus_tag="MIV85_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2960556.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            complement(47819..49261)
                     /locus_tag="MIV85_001191"
     CDS             complement(47819..49261)
                     /locus_tag="MIV85_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBY2960557.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEVSNYTNIQHV"
     gene            complement(49388..49774)
                     /locus_tag="MIV85_001192"
     CDS             complement(49388..49774)
                     /locus_tag="MIV85_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBY2960558.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPITKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            complement(49811..50200)
                     /locus_tag="MIV85_001193"
     CDS             complement(49811..50200)
                     /locus_tag="MIV85_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBY2960559.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            complement(50232..50768)
                     /locus_tag="MIV85_001194"
     CDS             complement(50232..50768)
                     /locus_tag="MIV85_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBY2960560.1"
                     /translation="MNLKGTKTEKNLIAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            complement(51145..51927)
                     /locus_tag="MIV85_001195"
     CDS             complement(51145..51927)
                     /locus_tag="MIV85_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960561.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSINLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            complement(51937..52707)
                     /locus_tag="MIV85_001196"
     CDS             complement(51937..52707)
                     /locus_tag="MIV85_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960562.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            complement(52691..53614)
                     /locus_tag="MIV85_001197"
     CDS             complement(52691..53614)
                     /locus_tag="MIV85_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960563.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            complement(53762..54697)
                     /locus_tag="MIV85_001198"
     CDS             complement(53762..54697)
                     /locus_tag="MIV85_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960564.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPYDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDRDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTIFTVSLPLI"
     gene            complement(54694..55386)
                     /locus_tag="MIV85_001199"
     CDS             complement(54694..55386)
                     /locus_tag="MIV85_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960565.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            complement(56047..56895)
                     /locus_tag="MIV85_001200"
     CDS             complement(56047..56895)
                     /locus_tag="MIV85_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2960566.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            complement(56923..>57190)
                     /locus_tag="MIV85_001201"
     CDS             complement(56923..>57190)
                     /locus_tag="MIV85_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBY2960567.1"
                     /translation="GKIHDDYRIDYLRSHINACKLAIEDGVEMIGYCPWSFTDLLSSS
                     QGFNKRYGLVYINRTDHEILDLKRIKKDSFYWYKEVIENNGIVK"
BASE COUNT        18695 a        10200 c         6305 g        21990 t
ORIGIN      
        1 ttgtaagtat cataggtagt aatggaactg gtaaatctac tttattaaat ataatatccg
       61 ggcttataaa agaatcttct ggtcaagtat tattaaataa acataacttg tctaatttag
      121 ctgaacacag aagaactcaa atagtaagta gagtttttca agacccaagt cttggaactt
      181 gcccttctat gactgttaga gaaaacttgt ctttagctct taacaaagga aaactattaa
      241 atctaagaaa atgtcttcgt tacaaaagag atttcttaga aaatttattg gaaggtgtat
      301 ctcttgattt aaaaaaatac cttgatgttc aagtaaaatt tttatcagga ggtcaaagac
      361 aatcattatc actaattatg tcgtgcttaa caaatccatc agttttatta cttgatgaac
      421 atacagcagc acttgaccca aaaacatcaa atgaagtaat tgaattgact aataagattg
      481 taagggaaaa aaatataact acacttatgg ttactcacaa cttaaaacac gctcttcatt
      541 atggtgatag attgataatg cttcataagg gtgaagttgt attagatgta aaaggtaaag
      601 aaaaagaaca attaacagtt gaagaaatct tagaaaaatt tgaatatgca gtttaaaata
      661 atatatctat tgtattaaac tcggctttaa aataaagtta aaattacaat aattatggtt
      721 actttgtaat aattcatatg aatatatgaa catatataat aataaatttt tgagggggat
      781 ataaaaatga ttaataaaaa aagattggca agtttgattt tagctggtgc tcttagtata
      841 tctatgctta cagggtgttc acaaggagga gactctggta attcaaaaca agaaagtaat
      901 tctaaaggta aagaagttaa aaaaattggt ataactcaac tggttgaaca tccagcatta
      961 gatgccacta ggacaggttt tgtaaaagca ttagaaaaga acggatttaa agatggagaa
     1021 aatattgata tagacttcca aaatgctcaa aatgacatgc ctactacaca aagtattgcg
     1081 agtaaatttg catctgataa gaaggactta atatttgcta tatctactcc atcagctcag
     1141 gcagcattta atgctactaa agatatacct atacttatta ctgctgtgag tgaccctgtt
     1201 gctgctggat tagttaaaac tcttgaaaag ccaggcacaa atgtatctgg aacatcagat
     1261 tttgtttctg tagacaaagg tttagaactt cttaaaatat ttgctcctaa ggcaaaaact
     1321 ataggagtta tgtacaatac tagtgaagta aattccaaag ttcaagttga tgctttaaaa
     1381 gaatatgcat ctaaaaatgg atttaaagtt gttgaaaaag gtataactac ttcaaatgaa
     1441 gttaaccaag gtatttctag tttagttggc aaaatagacg tattatatgt ccctacagat
     1501 aacttagtgg cttcttctat gcctatagtc tctaaaatag ctactgagaa taaaatacct
     1561 gttatagcag ctgaatctgg tccagttgaa aaaggtgctc ttgcttgtca aggtatcaac
     1621 tacgaaaaac taggttacaa aacaggtgaa atggcagtta aaattttaaa tggcgaatca
     1681 gtatctgata tgcctgtggc tacatcagat gatacagata tcattgttaa tgaagatata
     1741 ttaaaagctt taggtatgga aaaaccttct aatgaaaata tttcttatgt aaagactaaa
     1801 caagaataga aagatatttt ctatatacga ttaatatgcc tgtttctata aattaattta
     1861 tagaaacagg catatatttt tattttaatg tattatctat ttaaagatta tatgtaaatg
     1921 ctcttaattt gtttgtataa atatgattgt ataaacttta tacaatcata tttattcttc
     1981 tattttcttt attactctac atggatttcc aacagctaca gtatttggtg gtatatcttt
     2041 tgtgactaca cttcctgcac ctattactac attatcacct atagtaattc ctggtgttat
     2101 gattactccc ccacctatcc atacattatc acctattttt ataggagaac catactctat
     2161 gcctgaattt ctaagttgtg catcaattgg atgataggct gtatagattt gaacgtttgg
     2221 agctaacatt acattgtcac ctatttcaat tttacataca tctaaaaaaa tacaatcata
     2281 atttgcaaag aaattttcgc ctacatgtat gttatatcca taatcacacc taatattttg
     2341 ttctacattt atttgcttgc caactgaacc aaatagttgt cttaaaatat cttctctttt
     2401 ttcatattca tcctctaaag tattattaaa caatctagtt aattttttac aatactctct
     2461 ttcttttact aacaattcat catttgcata gtatcctttc ccagacaaca ttttttcttt
     2521 ttcagtcata tagtttactc ctttttgtta taattgtatc taaagcaaaa taaatattcc
     2581 tgtggaaaat ctaaatatat tctgtcacct ttcttaaatc tcattttact tttttccaat
     2641 tctatttgaa taggtacaca ttcgttagat aaatcagttt ttctaacata tatagtatat
     2701 gtaaaaggat tttctacaat gttaatcaat tcgaaacata acttttcatt taaatcttca
     2761 ttagaatcca agaccttaat atgatgctcc ctgattccca catattctat attatcacct
     2821 atttctctat ttaatgtcaa ctcgcatccc cagtctgtag cataaatagt atttttatcc
     2881 agtctattta atttggatat atttttacac cctgttatct tagcttctat aaggtacttt
     2941 ggagattcaa agagctcttt tttaggtctc tttggaagac cttctccttt gttgtacact
     3001 ataatatcat cacaaactcg gtaagcttct tcaatatcat gagtaacaaa tagtatatct
     3061 cccttgtaat cttttaacat attcataagt tctttttcca tattgcttct taaatgatgg
     3121 tccagtgctg agaaaggttc atctaaaagt aatatatctg gagatgttgc caatgctcta
     3181 gctagtgcta ccctttgttg ttgaccacca gataattgcc aagggtatct cccctcaaac
     3241 ccatttaatt taagtatatc taagtacctt gctactattt cctttttttc actcttactt
     3301 agttttaaaa gcccaagttc tatattttga cttacagtca tatgtggaaa caaagcatag
     3361 ttttgaaata aaaatcctac ctttctatct tgtgttgata aatttatctt cttttcagaa
     3421 tcaaatagaa ctctatcatt taatacaatt ttacctcttg ttggtttctc aagccctgct
     3481 atacatttta atgtcatact ttttccagaa ccagattctc ccaaaaaccc cagagtacct
     3541 ttttcttgtt taatttctac ctttagttta aaagaggata aatctttttc aatatccacg
     3601 tataagctca actatccaca cctctttcct ataattttct gctgaaattc cgaccaataa
     3661 tttagtaata aaatcattgc tatagatatt gctacaataa tcataaccca catcatagct
     3721 ttattcatat ctccgccttc aacagcaaaa aatatagcta ttggcatagt ttgagttttt
     3781 ccaggtatat ttccagctat cataagtgtc gctccaaatt cgccaagagc tctggcaaac
     3841 gacagcacca atccaccaat tattccaggc catgctaatg gaactgcaat cttaaaaaat
     3901 actttccatt cattaagacc taatgttcta gcagctgaca acatattatt atcaatctgt
     3961 tcaaaagctg accttgaagt tctatacatc ataggaaaag acaccactac tgctgaaatt
     4021 acagttgctg tccaactaaa tattaaagtc ctatcgaaat ttaataaaaa ctttcctata
     4081 aatccattct tcccacatag taataataaa aagaaaccta caactgttgg tggcaaaatt
     4141 agtggaagtg taaatagtcc atctataaga cccttccact tacctctata gttagccata
     4201 atatatgaca caaatattcc tattacaaaa gttattattg ttgacaaaat agatgtctta
     4261 agtgatatcc ataagggtga ccaatctgtt cccatctttc cctccttaat tttaaatgga
     4321 aatagtgaaa ctaataactc tattaatttc actatttcca ttttattata atacacaatt
     4381 attttcaatt ttcatttatt tatatataat ttatacttaa ttacacataa tttatttcta
     4441 agtttattct acttttttat atccaaattc ttcaaaaatc ttttgtcctg actcacttaa
     4501 taaaaattct tcaaatttct tagcagcatc tacgttttta ctagctttaa ttactgaaac
     4561 tggatatgta ataggcgaat gagttttttc gtctgttttt tcaactactt ttatcttatc
     4621 attattgaca gtatcactga agtaaacgaa tccaacatca gcatttcctg attgcaccca
     4681 tgctaaaact tcttttacat cttttgcaaa tactagctta tcttttaact tatcttttaa
     4741 atttaaatta gttaacacct catctgcata cttaccagct ggaacacttt cagcttcacc
     4801 aacagcaatt ttcttcactt tatctgtagt caaatctttc atacctgata cactactgtc
     4861 agcagaagaa ataagaacta aatcattttt tactaaatct ttcatagtat cagaaactaa
     4921 taacttctct tcatccaaag ctttcatttg tttttgacct gctgaaataa ataaatcaca
     4981 aggtgctcct tgttctattt gttgttgtaa tgagcctgat gctccatagt taactgtaag
     5041 ttttacattt gaatcaactt ttttatattc ttcttcaatc tttgccattg cttcttttaa
     5101 acttgcagca gccgatatat ttaactctac tgaatcacta cttttagttg ttttttcttg
     5161 ttttccatta tcttttttgt cttcattact attgcaccca actgtcccca aagttaaaca
     5221 tgcaactaat cctaatattc ccaatatttt tttcataaca atctcccttt ttgtaaattt
     5281 gatacacatt ttaacatgtt ttattatgtt ttatcatgtt ttgttatata tagtttaatt
     5341 atatatacat gataataaat tttcaagtaa tttatttaca ctacttttaa atattttgct
     5401 acattttcct ttttttaatg ttaaaataac cttatatgga ggtggattat ggactcatta
     5461 tcatctttga cacctgtcga ggtagctgaa ttattaaaga taacaaaaaa tactgtatat
     5521 gaattaatca aaagaggtga acttccttct tataaagtag ggaaaaaaat aagagttgat
     5581 actaaagatg ttgaagaata tatcaacagc caaaaaactg gtaaagtaaa ggatacacat
     5641 ttcaacaata aaaatataga tataaataat aatttcaaaa ttattatttc tggtcaagat
     5701 gtaatattag acattttagc taggtctgtt gaaaaaaaat tggatggaat aagtacattt
     5761 cgctcttata taggtagtta taatgctttg tatgagttat ataatggcag agtttctata
     5821 gcatcatccc atctatggga tttcgaaacg gatgaatata atagcacttt tgttaaaaag
     5881 ctattgccag gaataccatg tgtacttata aatctagctt atagaatgca aggtttctat
     5941 gttgctaaag gaaatcctaa agagataaca acctgggagg atttaacaaa accaagtata
     6001 accattgtaa atagggaaaa aggttctgga actagggttt tactagatgg taaacttaga
     6061 cttctaaact ttaatggtaa acatataaaa ggttatgata atgaagaatt atcacatctt
     6121 ggagttgcaa gtactgtttc tcgtggaata gcagatgttg gtttgggaaa tgaaaaagct
     6181 gctttacaag taaataatat cgactttatt cctcttcaca aagagcgcta tgatttagtt
     6241 attaaaaaag aagacttaca aaatccagtt taccaaacta taattaacat aataaactct
     6301 cctgagttta aagctgaact tcaaggtctt ggcggatatg atttaactga tactggaaaa
     6361 actatagcaa aagtttaaga ttaaaatcgc aatctatttt ataagattta taatttttca
     6421 caaaatttat aacttaaaca cgaaataaat tgcgatttta gtgtctcaaa aaatttatgt
     6481 ctttcatttt atcatccaat acaaaatata atataattaa ttgtgcaatc atattatatt
     6541 aatatatatt tacataatag tatttttctt taatgtagat taacatatga tatgttttaa
     6601 acatcaatcc ccttgctttc ttatatatat ttggcaacac atatgagttt aataaattat
     6661 atacaatgtt gctttcttct tgtatttttt caaccaacaa gttatttata aaattacctt
     6721 tctcattttc aataatctca ctccaattta tcttaacttt taatatatat cttcccacta
     6781 ggtatacaca ctctacaata aataataaaa atacaatgca gtcagtacct gttgtcttat
     6841 ataaattacc cgatactaat ggctttgcga agaaattata aaaattcaaa gtatcacccg
     6901 tataatcaaa aagtattaat agcactccta gaactctcaa tactttaata ttcaacatgt
     6961 ttttatcttt attatttttg tttttcatat atactacctc tcttttcttt agatttgatt
     7021 gtaatctaat actaactctt ttatttgagg tataaatgaa tttaattggt agttattttc
     7081 atttttacta gaaattaatt cacattacta aacaaaactt atatttaaac ataaaaatag
     7141 cctatctatc ttttaataaa tacaaaaata aataagctac taatattcaa ttaactttta
     7201 tcacttaaaa cattactatc tataaattta aatattttat tgaagtatac tgtactatca
     7261 tgttcaaatc catcaacatg accaatacct tctataagcc ataggtcttt tttatcatgt
     7321 ttaactaaat catacatttt cttgctattt tgataattac aaacagtatc ttttgttcca
     7381 tgtataaaca gtatgggtac attagatttc tcaactgact catatggttt tacatcactg
     7441 taccaaaatc cagatttaaa cttattatat aaatctccac aagtcaccac ataattgatt
     7501 aatatatctg gtattcgttt ttctagtact cccattctaa ttgcatcttt catttcagaa
     7561 taaggagaat ccagtatata aaaatcgacc ttatcatctt ttgaatttat ctctgaatgc
     7621 atagcagctg tccctgcccc catggaaaat ccatgcacac ctaatctccc ttcaggaaat
     7681 ttatttttta caaatttaac tagactatct aaatcatacc tttcataaag accaaatgtg
     7741 taattatctc caccactatt accagtattt ctttgattat aaactaatac attataacct
     7801 ttatctaaat atctatatgc tacctttaac atttcatagt aactacttcc aattccatga
     7861 acaagtatca tagtatctct tgtctttata tttgaagtta taaaaagact ttcaagcttg
     7921 taattattag aactttgtat cattaattca gatgtcttgt agttttttaa tttctccagt
     7981 ggtttatctt ttctctcaga aaatattttt actatatctt cgttttttat taactgctct
     8041 aaaccaactg aactattata cactaatttt ccaaatatat aagatacaat taataggatt
     8101 aatagaaaca caattgatat aattataaat ttatttctta aactaataca atttttaaaa
     8161 ctatttttca tatttattta ccatacaatt ttcctatatt atattttcta agtaatagca
     8221 taattgatta tactattctt ataatttcta ttatacctac ttatttatta aaaatacaaa
     8281 ttatatttta ttaattttta ctacttgtaa attattatct tatacaatga atttgtatta
     8341 tataataagt atttttagga ttctgttaca taatattatt taaatattct tctatatttc
     8401 tcttcttctt cttcagtaaa cacattaaat acaactttta aatttttttc aggattttct
     8461 tttagccata gtctaactct acttacagca agattagctg cctctttttt tggataacca
     8521 aatacacctg tagaaattcc acaaaaaaca atatttttta tttcatcaat ttcttttatt
     8581 gtatttaaac atgatttata acaatgaagc agttgctttt cttgctcttt acttggctga
     8641 ccaccagata caataggtcc aacagtatgt actacaaatt ttgcaggtaa acaataacct
     8701 ctagttatct tagcatctcc agtatattct aaatgccctt gtttttttat tattttgtca
     8761 caatcttctc taagtctagg acctgcgcat gaatgtatct cattatccac gcatagatgt
     8821 aatggttgta aacaccctaa taacttgtta tttgcagcat ttactattgc atctgctctt
     8881 aaattcgtta tattacctct ccatatggca atcccttcct ctacttcttc tatatcattt
     8941 acatctacta actctctttc ttcacattca atcaacaata aattatgtaa catattaagt
     9001 atctctggag caatttcttt tggtggatat acattcaaaa gtcctctaag tatatctcta
     9061 ggcttaattt catcatttga taaattgtat attttagaag gaacttcttt tgaaaaatat
     9121 gcaattaaag tgtttatatt ttttcttctt tgttcgtcag ttagaggctt gatagtttta
     9181 tcaaaatcct caaataaatt tacatcatca gcataatctc tccacttcat agccatctct
     9241 ccattcttgt attttagact taaaaataat tatgtattta tgtacatatt tatttatttc
     9301 tataaacacc tacataaatc ctgttaaaag tgtaaatttt ttattataca acttctctgg
     9361 ttatttctat tgattgatag taaattattg tacctaaatt taatccaact aacaagtaac
     9421 taaacctact ttcctaactg caaaatacac tatgtttgcc acttgtatct catttgtaga
     9481 taaataaagt ccctacaaat acattaacta ggctatgtac taaactgtag gaactttaaa
     9541 aatatattat tcttaattaa gttttggcca ataattttta tttgcttcta ttaaatcatc
     9601 tagtaattct tttgcaactg ttgcactagg aactgtctta gatagcataa gtgcttgcca
     9661 caatttatta taagacttct caatccaagc atcaactact aatttttcaa ctgctaattg
     9721 ttgttctatt aaaccttttt ggaatgttgg tattttccct attgataatg gttcataccc
     9781 gtcttttcca actatacatg gaatttcaac catagcatca tcttgtatat tttctatagc
     9841 tccattattt tgaactatca ataacatacg ctcctgtgta ttaaaagcta gagctgtagc
     9901 taaatccact ataaactctg catgtattcc tatcttaagc ccactgccct tagaatgtcc
     9961 ttgcttttct atcaatgcac atgaaccaaa aacttctttt tctcttccat caataacttc
    10021 attggcacga gtataattta catcagaatg atttacaaca taatctggaa atagatagta
    10081 ctttaagtaa ctacttggta ttgtagttaa atctgttttt actatttctt tagtaaataa
    10141 attagtttca aaccaactat ctttcttgtc atttttcatt ccttcttcac catttataaa
    10201 accatattct tttatatgtt ctactaattt tggtaaaagt tcatttcctt ttttatcttt
    10261 aattgaagta taccaaccaa agtgatttaa tccaaagtat cttatatcca tatgtttacg
    10321 agatttgagt cctgcaatcc ttgctatatt atgttccata cctattggca tatcacaaat
    10381 atttattacc ctagaattag gtctcaacct tctaacagct tccgctatta ttgatgctgg
    10441 attagaataa tttaacatcc aacaatttgg agaatacttt tccatataat ctatgttttc
    10501 aagaacacct tctatagacc tcattccata agctattcca cctggtccac aagtttcttg
    10561 accaactacc ccatgtttta gaggtatctt ttcatctagt tctctcattt caagttttcc
    10621 aactcttata tgagctaaac aaaaatctac atctgtataa gcctctttag ggcatgttgt
    10681 tgctaaatac tctatattag ggtccttttc ctttattagt atttcacaag ctttagctac
    10741 cttattttgt ctttcttcat cattatcata taatttgatt gctcttaatg gtaacctatc
    10801 taagttatct agcaacatta atatgatttc tggggtatat gtacttcctc ctccagctat
    10861 tactactgaa aatttttcca taataatatc tccttttcta tttaaaaatt tactgtattt
    10921 ataaataaat ttataaatac tagtacttta aagtaaaagg gagttcattt attaaatcta
    10981 ttgatttaat aaactatagc caaacttcaa gcactattta caagaaattt aattcttatt
    11041 aattcttggg tccatcatct caaatatatc tacaagttca gatactaaag aatgagcaaa
    11101 taatgcattt gaataatggt cttcagagtg cacaactaaa aaatcagtcc cactatcttc
    11161 actattcata gcatttgata gtaattctaa atgatgcttt gatgctgttt gtattttctc
    11221 tgaggctgaa tttaaaaggt gttttgcttt attgtagtca ccttttttta tttccttaag
    11281 agacatcatt acatcacttt tagcatctcc tgcttctgat attatactaa atactttttc
    11341 ttccatttca ggtaccatat ccttctcctt ctaatgactt gttaaaaatc aaagctatca
    11401 tcatctaatg ttgtagctaa ttctgcattt ttatttaatt cttccttctc cattatctta
    11461 aagaatggat aatatatcaa ggtcataagt attatacttg caaatactaa tacgattgcc
    11521 ttccaatcta atgtcatcaa aaatgctgca acccctggag gtaaaaagcc tggtggttct
    11581 gcaataggta atcctactaa tcctactttt aatgccataa aattaagtgc tccaaccaat
    11641 acaggtccaa atacaaatgg tacaaacata tatgggttca taactattgg tgttccaaat
    11701 attaccggct catttattcc aaatagtgat ggtaaaatca caacttttcc catactatta
    11761 aaactcttac acttacttct tgacataagg tacactaatc ccaaagttat tcctgaacca
    11821 gttacttgca agaaaccata gtaaaatcct attgtaaaca catattttgg gtctcctcct
    11881 gctgctatca gtgttgcatt ttctgccata tatgtagctg ctattggcat ccatatactt
    11941 gaagttattg ctgctccatg aagcccaaag aaccataata attgagttat aaatagtatt
    12001 atagttactg caaaaacatt atctacactg cttatagctg gtgctaagaa attcattata
    12061 atagctggta gtggttgacc tgagacattt ttagttattg ctgctattgc tgtaaataac
    12121 attatacata ctatcattgg agttaaattt ctaaaacttt tatttactac actaggtact
    12181 tcttttggaa atctaattac gagattttta tcattcataa acttagtaat atcaactact
    12241 aaaagtgcta ctaatatact tacaaataaa ccttgtgcat ctaaataact tgtatctaat
    12301 acaccatcta ctacttgtcc acatacaaca agttgtgcaa caactgctgt catgcctatt
    12361 tctacatgat taagattata ttttttagct agtgcctgag ctataaaaaa tgctgaatat
    12421 atagataata aactcatagt aaatttatta gggataagta atgtatccat attttcagat
    12481 aataatgttt ttgcacttcc ttcaggtaac atattgttta atgccataaa taacatactt
    12541 aaagaaccaa caattattat tggggtaatg cttatcatac cttcttttat agcttgaaga
    12601 tgcctttgtt tttcaatctt ttgtgctatt ggaagaagaa atcttcttaa attattttga
    12661 agtgcttcca tttttattcc ccccaattat ctatttttat ataattcgat tgccgacttc
    12721 ataacagaag gagcatccat acgaccataa tgcttagtat ctattaaacc aactgctatt
    12781 ttgtaattct tacaagcttc aactacatca tcttccttaa acctaatttg tggtgctaca
    12841 agtactacat ctgtatcatt agcttcaatg tatgatttta aattttcaaa tgatgttgcc
    12901 tctatattta tagttttagt ttttaacttt tcatgctcac tacaaaaact tttcatcttt
    12961 tccacaagta cacctgttga agctccattt gcacatacta ataaaatatt cataattacc
    13021 ctcctacaat atctaacctc ttttattttc taatttttta tcagccaatt cttactctaa
    13081 ttcctatcag tttttacttt aattcttatt attttatttt aattcttatt aatatttact
    13141 ctaattctta gtactgccaa tgattaaact tgaaagccgt atctataact tcttcttgct
    13201 tatatttttc taatattttt aagtatcttt ctttataatc attatctact tctttttctg
    13261 gtattactat actagcttca tttaaaaagt ggaatgaatc ccttcccatt tctaatcctc
    13321 tatatgtatg cttgtcaagt gccacgtcca taacttctgg aactttaccc attgcaaatc
    13381 cttttataat tatatttttt aataaatcac ttgatctatc tttctcacat gcacaaagat
    13441 atcttattgc atgtatgaaa aataaaggtc tgtctccatc tgcatatgaa tattcctttc
    13501 ttacttgatt taaattattt atgattatta cagctgatgg atcccccatt cctatatctt
    13561 caactgatat tgtaagtatc cttctccata gcttatcttc taattctggt gatgatatat
    13621 atagttcata agcaaattca caagcttctt ccaccatatt tcttcttata gctttttgaa
    13681 atgacgatat tatttcgtct gcactaaatc cgtttcttgt agtcattctt gcccatgggt
    13741 catttgcctt tttatctctt aatattttat cttgcatatt atttactcct ttttatttaa
    13801 attttaatta tttatattac tcatttaata atataagcaa gtattatgcc agttttttta
    13861 gacactttaa aacactgtta tttcaatcat ttttatcatc aaaacttaga tactttgtct
    13921 aagtatattt atatgtgtct aatattaata ttattttaga ctaaaaaaaa attaccaaat
    13981 aagtttttat actcattggt aatctttttc gattatttct gcatattcta atattaataa
    14041 tatttgatag cactcttttt cattaatttc tatattatat tttttatcta attgagatac
    14101 tatatctttt attttgctta gactcttgtg ataatcaagt gttttttctt tatcaagctt
    14161 ttcaatttct ctagtatttc caatcaaccc atctaccatg aaagctaaat gcatcataag
    14221 tccaattact ttatcgtatt tcttttctat attaaatact aaaaacaatt catcagacac
    14281 atattttata tctttaaata ttctattata attagagctt tttaaggatg tctttaaacc
    14341 ttcaactaca tcatcataac ctatacttat ctttataata ttttttaatt tattgatatt
    14401 ttcatcctta tctatatctt ttttgctaat atagtcaatt cctctaatat taattctttg
    14461 ttcattgatt actgcaacaa tattactact ttctttaagt ttcgtaatat ttaaacttaa
    14521 atctttttct gttttatatg ggacagatat aatatctatt ccatctaagt acctactcat
    14581 cttttcttct aatatttttc ttgttttatt atctacacct tctgaaacat gtgatgctat
    14641 aataattgtt ttagacagat tttctttatt ttgaatttca ttagttccaa aatagtgctt
    14701 tctcgtgtta gtgatagagt tgtatacgtc atttaaaggt aatcccatat tggccttctg
    14761 aactgcttct aacacagtta atgtcgtcac cataggaatt actcttactc cacacttttt
    14821 ttctttcttt ataatttcat caaaggagtt taatgaaccc atatctgtaa atagtaatac
    14881 atctttattg tctatattat taattaaatt tttaaaatct acaataactt catcatagct
    14941 tttatctaac ttcatatcga aagaaatagc actgcacttt ccaataatat caccaactgc
    15001 ttttaccata ctacttgctg tagtttctcc atgcatagca actataatat taatgttatt
    15061 cactatttta ttttgttcat cttgtttagc ttgtactatg aataatgtaa tatatgctac
    15121 agtttctata gataaaaata aatcaaattc attttcaatt attccaacta tttttaatgc
    15181 tgttttaaat tcacttctgt tatttcttct aatttgattc aaatctatgt tgtttgtaga
    15241 gctactttta tccaatacgc tttttatata aattgccatt gacttaaata ttgattcact
    15301 tatgtctatt tcttcatctt ctttaataat ttgtcttatt gattcacaca tgcttttaaa
    15361 cttaacatta ttaaatagag aagcatctgc tatattcatt tctacagatt tattaagatt
    15421 agtatttact gcattaataa tatttatatc attgtagtta ataacttctt cttctcctaa
    15481 tgacgtaaat acaaaatatt ctattccatg tgttataact tcatctgctt taatagactt
    15541 ctctctataa tcatcactca cttcatttat agatttatca aaatattttt tctctatata
    15601 aactggttct ttattatctc ttttatatct tagatatcca tttgcaacag ctaattttat
    15661 atcattttga agttgaccta cattattttt acaatcataa agtaatagtg atttaattat
    15721 ttctttatgt acttttattg aaatagaaat actttttgat tcttccttga aaaaattttt
    15781 gactaattcc attctttcaa tcattgtcct atctctcaat gatggtattt ctattttcat
    15841 tggtattctt ctattgaatg tatctaatag tgttgatgtc ggattttctg tagtagcaca
    15901 tattattaat accttagact ctctttcttt cgttgcatct cctagtcttt taaatgttcc
    15961 cttatctata aaagtaaaca acatttcttg accttctgct ggtagtctat gaatttcatc
    16021 taaaaatagt atccctccat ttgcaatttc caaaagacct tttctggaag attctgcacc
    16081 tgtataagct ccttgttcta ccccaaaaat atgtcccata agtaattgtg cattattagc
    16141 ataatcagca caattaaatg ttacaaaagg agctttattt tttctaattc cactatctat
    16201 agaataatcg tacatatatc tagcaatcat actctttcct actcctgttt ctccatagat
    16261 aatagtatga agtccatttg taggatagag cattgcgacc ttgcattttt ctattatagg
    16321 tcttaaacta tgttctttac ctattagtgt ttcaaaacta tcttttttta ttttgttttc
    16381 tacttttgtt ccttttttta tgccaagcaa ctcactttgt gtatcaagca attcattctt
    16441 gttaaggtta agatttgcag ggatataata cacaggtctt ccttttatct tcgtaaccat
    16501 accctcattg aataattggt ttaaatatgt acttatattg tttcttgcaa ttcctgtctt
    16561 ttctgataat tggttagctg taatcccttt ttcattttcc ctatatgatg attctaaaac
    16621 tttcattact ttatcttttt tatatatcat tacaagctcc cctacattat agtattttat
    16681 taactaaaac ccctatacac actttatttt ttaataaact cttattcttt aactaaggtt
    16741 ataatttatc aaactttcct tactttaaat tatagaaaat tattgtagaa aaaataagat
    16801 tattgctcat tttttctaca ttactatttt taattttata gtactttctt aacaacatac
    16861 tttacttgtt tttaatttta ttatatttga atttattata tttgaaaagt agaaataaaa
    16921 aaccctattt tggagtagtt ttaaaatttc tccaaaaata gggttttagt ttgtatttca
    16981 aataaatacc tgttcaagta tttttatact aaacaacttt taaattttgt tgatatttat
    17041 ttatttctga tttagaagaa tatacaaaat gtccatctga aacctcaatc caacttaatg
    17101 acttttcatt tgaacaatca tatccattag aattatactc tattctattt cttgacttag
    17161 catatctagg gtcaggaaca ggaattgcag aaagtagtga ttttgtatat ggatgaatag
    17221 gattattata caattcattt gaatctgcca attctactaa ttttccatta tacataactc
    17281 ctatacggtc actaatatgt ctcaccatag ataaatcatg agctataaat aaacaagtta
    17341 aattcttttc ttgttgcaat tttttaaata aatttactat ttgtgcttgt atagacacat
    17401 ccaaagaagc tataggctca tcagctatta taaattctgg gtctactgaa agagctcgtg
    17461 ctatgccaat acgctgtctt tgtccacctg aaaaatcaga tggatactta tttgcataac
    17521 ttctatcaag tcctactagc tttagcatct catatacttt attcattcta tctgttttat
    17581 ttttacagat accttgaatt tttagtggct ctgaaattat atctgcaatt gtcatacgtg
    17641 gatttaatga tgaagtagaa tcttgaaaaa taatctgcat acttttgttt acatcttttt
    17701 ttataaattt gtacgttttt ttatctgata tgcaatttcc tttgtaaatt acttctccac
    17761 cagtagattc atgtagtctt attatagttt taccagttgt agattttcct gaacccgact
    17821 ctcctaccaa tccaaatatc tcacccttat atatatcaaa acttatatca tcaactgctt
    17881 ttacagtagt acttttgtcc aaatgaaaat attgctttaa gttttttatt tccagtattt
    17941 tttctctatt cattagaaat cacccttcca caatttactc taactggtac atctacttca
    18001 ggtgcatctg ggtgcaataa ccaagttgct gcactatgtg tatcattaat tttaaacatt
    18061 ggtggctctt tttcataatc tatcttaagt gcatttttat tccttattgc aaaagcatct
    18121 ccttttggtg ggttcaataa atttggaggc attccaggta tattatataa atagtcatcc
    18181 tgcgaatcta aagtaggtaa tgaacccaac aacccccaag tatatggatg tctagggtca
    18241 taaaatatat cctctacagt tcctatttct acaatctttc ctgcatacat aactgctatt
    18301 ctatcagcta tagttgcaac tactcctaaa tcatgagtta taaatattat tgacaaacct
    18361 attttatgtt gtaaatcctt tattaaatca attatttgag cttgtatagt tacatctaaa
    18421 gcagttgtag gttcatcagc aatcaataca tctggattac aagcaagtgc tatagctatt
    18481 actatacgtt gtctcattcc acctgaaaaa tgatgtggaa attgtttaaa tcttttctca
    18541 ggattatcaa ttccaaccaa ttcaataagc tctatggctc tcttttttgc ctcactttta
    18601 cttatacctt gatgaatgat tacagcttct gcaatttgct ttcctattga tatagttgga
    18661 ttgagagatg tcatagggtc ttgaaatatc attgatatat tctttcctct tatatcttcc
    18721 atctcttttt cagacttctt aaccaaatca cttgatttaa gtaaaacctc tccattttta
    18781 atatatccat tgtatgggag tatcctcatc aaactcttac acagtacaga tttcccacaa
    18841 ccagattctc caactatagc caatgtctca ccttttttta gattaaaaga tacatttctt
    18901 acagcctgaa cttctccttc ttctacttta aaacttacag atagattatt aacctccaat
    18961 aaatgttcca aaaaccatca acccctatgc tattcaaacc ttagggatat atttttatcc
    19021 ctaaggtttc taattaattt cagtattatt caattgtcca gtcagctatg ttccagaata
    19081 cacctacacc atgatgacct aaaactgtat caggtgttaa tccttttatg tttggttttc
    19141 caacatatat tgcatctata taagcaataa atgtataagg catatcctta gtcatttcta
    19201 cttggaattg tttatataac tttaattttt catctttatc ttctgtttct cttgcttttt
    19261 gaagtatttt atctatagta ggattagagt aagcactgta atttgcacct ttatctgttc
    19321 caaatacttt atatgtatgg tcatctgggt caaatggact tccccaacct attaaatgag
    19381 catcttgatt agcccaatct gtttcagtta caacaacagc tttagcatca acaccaattt
    19441 cttttaactg ttgtgcacat attttagcca tatcaactct aacttggtca ctctcacctg
    19501 ctgttatctc gaaagctaac ttagtacctt ctttttcata gattccatca gaacctaatt
    19561 tccaacctag cttttcaatt tcttgtttag ctttttctgg attatattca aacttttcta
    19621 tatcaggatt attatatggt cccatttgta aaggtgaata tgctggtaca ccatgtccta
    19681 ataatacact gtcaactatt gcttttctat ctattgcata gcttaaagca tttggtaatc
    19741 ctttagcttt tttatcttta aagaatttag aattaaaatt gtataatata cctctatagt
    19801 cggctgtttt cattatattt actttaaaat tcttttcgtc tttttcaaag ttagacatat
    19861 ctttaggagt tatttgagct aggtctaatt ctcctgattt taattgcatt gccttagcct
    19921 tatcatctgg aacaatctta aagactactt tatctaatcc tggttctttt acaaaataat
    19981 cactattctt aacaagtgtt atactttgac ctttgtccca tttttcaagt ttaaatggtc
    20041 cagtacctat tggtttttga ttaaattcat cagtagctat atccttaccc tccaaagcat
    20101 gttttggtaa tactcctact gttaaataat caagcattgc tgtatttgga gcttttaaag
    20161 taatttttat agtattatca ttaaccacat caatttttgt tatatcttca taatttgatg
    20221 ctatctcaga agcattatct ggattcatta tagtttctat tgtaaactta acatcatttg
    20281 ctgtaaattt ctctccatca tgccacttaa catcatctct taaattaaaa gtatatgtat
    20341 ttgttgcctc atcaaatttc cagtcctttg ctagacaagg aaccacctta ttattttcat
    20401 catgagctgt taatccatta aatattaacg aatttatttc tccatgttca tatagtgcag
    20461 gatttatact tgtatagtca ttacttccat aaacaagcac ctttccatct ttaggcgtat
    20521 ctgccttctt atctttgtct cctccactag aacaacctgc cattagacta agtatcatta
    20581 ctaaacttaa aacttttaac ttctttaatt tcatgatgct cccccttttg ctttttataa
    20641 aatatttttc aaagctttga ccccatttat ttaaatagat atttcaaata cctcagtatt
    20701 tgcttattta atactcaaat gctgatttat aaattactag attttttatt attattcttt
    20761 cttatataat tacctatatt tgttatacac accaatgtgg taaccaaaaa tatacccgga
    20821 atcagtataa tccaccatct atttgaaagt aatgcttcct ctgacaaaga taacatactt
    20881 ccccaagaaa caatttctat tggtaaacca attcctaaaa agctaagtgt cgattcagta
    20941 ccaatagctg cgcctatgtt tgttacaacc atgaacatta ttgatgccac aaaatttgga
    21001 agtaaatgtt gctttaatac atagaagaat cctcctccca tgctcttagc tgctagtatg
    21061 tattcgctat tttttatttg tctaacttct gttctcacta tcttagatat attcatccaa
    21121 cttgttatcc ctattactat ggacatagat actggatttg aatttccaag tatagcttgt
    21181 acaaatatta taattaatat tgaaggtata ctaagtatga tttctgtaaa cctcatcatt
    21241 gcatcatcta cgagttcaga tgccgaacca cttatactac cataaacaat tcctataaca
    21301 gttgatatta cagtggaaaa tagtcctata aataaagata tttttcctcc ataccatatc
    21361 atagaatata tatctctacc cattgagtct gttccaaata aaaaagtttt atttggagct
    21421 aaattagaac ttgctaaatc catgtatgtt ggttcatgtg tcattataaa agatgagaat
    21481 acacttccaa tgactatgat tgataaaata ataattgata tatatggtaa ttctttaatt
    21541 tttttagata aggttttctt tgtttctata tgttcatctt ctgctactaa aatataattt
    21601 tctcctacaa tttcaaaatc actatattgt ggcttcatta gtatcacctc tatcatattt
    21661 cattctaggg tctattttat tgtttataat ttgagctaac atattcccaa atactactaa
    21721 agcccctgtt attaagcata aaactaataa catattataa tcatgatact ttgcactttc
    21781 aaaacaaagt gttcctaacc caggataaga aaaaactttt tcaactacat aagttcctcc
    21841 tagtatatga ggtatcgaaa tggccattat actaatatat gatggcatta tatttctcag
    21901 gcaatgctta aaaacaatag ttctattatt taaacctttt gctttacata aaagcacata
    21961 atcttctctt atttcctcta gtaatttatt tcttatcata tatgtgtaat accatagatg
    22021 gcttaatata agtactgtaa gaggtaagat tagatgtgat atcctactta atatactgga
    22081 ctcttctccc attgaataag caccactact tggaagtata cttaagttta tactaaatat
    22141 aagtatgagt actaaggcaa cccaaaatga tggaatacag ttggttattg ttcctaattt
    22201 gcatatgatt ctatcaatga gcttatcttc atgtaatgta caaaatattc ctaacaataa
    22261 ggctagcaca aaggtaagta tatatcctga accacctaat attatagtgt ttatatagac
    22321 atcatttata acagaagtaa cattttgttt atatttaaat gaaattccaa attccccttt
    22381 tgatgcattt gaaatccatt ttatatattg actgtatatt ggttcatcca aaccaagttt
    22441 tttcatagca ttttcttttt cttgtgtact cattctttct actccatccc catagtaaga
    22501 gattaatggg tctcctggag caagtcttgc catgtaaaaa acaataaaag ataataaaaa
    22561 cattactaaa ataaactgca acaacttttt cagtatatcc tttaacaaac cccaaccccc
    22621 ctttgttgca ataaaaaaaa ccacataaaa gcaaacgtaa agtaacgtta aaaccttcgt
    22681 ggttccatta tcattaaaca aaattaaatt ttctatattt atctatgagt taattttagc
    22741 atcatttatt aactgtgtaa acaaactttt taaaaattgt taaaatttca tcaaattatt
    22801 ttatttatac ctaaaataaa atttttatat tctattcttc attattttct ataaaattat
    22861 aaaattttag gttgactata taagaaaagt atattatatt agtttgtatg caaaccattt
    22921 aagaggtgat tttattgaaa agtaattatg actgttttag aatagccatg ctcttaaaag
    22981 aactttattc taaaactatg tacacagtag aagaaaattt taaagaaaat ggattaacac
    23041 accaacagat tatagttata aaactgatag ctcataatca agaacttaca atatcacaac
    23101 tatgtgatga aatgtcttta gctaaaggta cggtttcagg cataatcagc agattagaac
    23161 agattggata tatagaaaaa ttcaagaaat ctaatgataa aagaaataca tacgttaagt
    23221 ttacaacaac aggatttgaa tttgccacaa attttaaaat taaaatgcaa gaaagttttg
    23281 atgatatttt taaaaattgt gatgaaaacg aattgagtga cttagtaaaa aatcttagaa
    23341 atatattggc aaaagtaaag gagagataat tatgaattat aaattaatac ttgcaatagt
    23401 atttataaca tcagctttaa ttttctacac tataggtgta tttggagaaa gaaaggcaaa
    23461 aattttaaaa aagaaacatg taattatatt ttggcttggt tttatatttg atactttagg
    23521 aacatttaca atgagtaaca tagccaacag ccatactttt gaagtaaaat ctgctttatc
    23581 acaaaacctt catagtatta caggtcttct tgcaattgtg cttatgcttt ttcatgcaag
    23641 ttgggctact tttgtcctat acaaagatga tgaggaaaag aaaaaattct ttcataagtt
    23701 tagtatagtt gtatggacta tatggttagt tccatatttt ataggtatgt ttattggtat
    23761 ggctggatag taaaataaaa agtgtgtaag aaatactgta ggtaaatttg tataagacaa
    23821 atttatctac atccttcttt cacactttta catatttatt tataatactc cattatttct
    23881 ttcatgtttc ttaataccta tatagaatat ttaattattt ctatagtatt ttattatttt
    23941 ctcacacttt ttcatatata tattgtttta ctatttcttc atatgtatat atgaaatatt
    24001 ccattatttc tataaatgtt ttattatctt tctcatactt tttcatatat atattgcttc
    24061 actatttttt cttatttctt catatacata tgaaatattt cattatttct ataatgtttt
    24121 attatctttc tcatactttt tcatatatat tgcttcacta ttttttttac ttctttatta
    24181 aatacttatg tataacatac atttaataaa cgctaactat taaacaccta atacttgagt
    24241 tactcctgga acttcactca ccaaaacatt ttcaataata gctttgattg tcatagtcgc
    24301 tcctggacac ccactacatg ccccttgtag tctaactaaa accacaccat tttcatttac
    24361 atctataagc tctacatctc caccatctct ttgtaatact ggttttatct tttcctcaag
    24421 cactttttca actttttctc tcatagctat tccccccaga aatattttat tagcaaaatt
    24481 ataccaatgg tttaaatttt tgtccatcta atgatttatc aaattcaatt tttgcttcat
    24541 caataatttt agtatccata aatacatcat aagcactaca agccagtact ttagctgaat
    24601 ttatcatagc agaaaatcct atatttgaac ctgctgatga acatgactgc catgtatgac
    24661 ttgcaattcc aacaggccaa gctgccattg caaattgagc cactggtatt acataactta
    24721 catctccaac atcagtagaa ccagctagtc ctttatcttt gtcaccgtca actatttcct
    24781 tgtgtatata gctttctaca atagatttat cattttgtaa tgatgttgct acacctaatc
    24841 tttcttctct agtaagagta tcacacaact tttttgcaaa ttcttcttct tcaggagtat
    24901 ttttagggca accaacaaaa accatattgt cataaactaa atcagtcaaa cattggtttg
    24961 gtatatagtc atatattcca tctgtaacct tatactccat ttcagtttct gtcatcattg
    25021 ctgctccttg agctactttt attaatctat caagaacgtg ttctgcatcc tttgcttttt
    25081 tacctctaat aaagtaccaa ctttcagcaa atccaggaac tacattaggt cttccaccac
    25141 cattagttat aacatagtgc attcttatag agtcaataac atgttctctc aaataattag
    25201 ctccaacatt cataatttca acagcatcaa gtgcgcttct accattatga ggagcttgag
    25261 ctgcatgggc tgttatccct ttaaatttaa attttacaga taagtttgcc agacttccac
    25321 ctctccaagg tgcatttata tcaaaaggat gccatgtaaa tgcacaatct acatcatcaa
    25381 aacagccatt tatacacata gctgtctttc ctccaccttc ttcttcagca ggacaaccaa
    25441 aatattttat tgttccatta aatttatttt cttctattaa tttttttata gaaacaactg
    25501 ctcctacacc tgctacaccc aacaggttgt gcccacatcc atgtccagct tttccttcta
    25561 ccaatggctt tctttctgca cttacacatt gtgatagctc tggtaaagca tcatattctc
    25621 caagtatgcc aatcacaggt ttaccctctc caaaacttgc tataaatcca gtaggtaaat
    25681 tttctacttc ttcaatttta aatccttttg actttaggta ttctttttga atgctacttg
    25741 catacttttc ttcaaaggct aattctggat tttcccatat tttcttagat aaatcaatta
    25801 attcttctct tatttcttca acattattta tgatatactc tttcataatt ttcctccaaa
    25861 tatatgtatt tttgatatgc tttacagatt atattatata ctaacattct atttattcac
    25921 aattttttgt taattaattt tattcatatg ctcttctatg gagtatatct tatcttcact
    25981 ttgcctcttc ataaatttaa tgtactctat cttccataaa gtagtttcag ttttctcatt
    26041 taacataaat tctaatatat taatttctct cattctaata tcttcataaa atactacact
    26101 acccaatatt gccaattcta attcacttaa tgatgcaaac aacattaaat actcttctcc
    26161 aaataaacat tcagattcaa gaatatcgat aaagtctttt ttagcattga tattttcctt
    26221 tattattctt attttttcaa ttatagatgt actatctaat atctcattga atatctctct
    26281 aaacgattca tcatccaatt tactttcatc atcaacaata taatcttcta agtgttcctt
    26341 tttattttta ctcacagtta ccatactttt aaaagtgtta ctttttattg agcttagcac
    26401 agattcaata aatatctttt catatttttt aatatatctt attacatctt catcttctat
    26461 gcttaatctt tttattaata cttcaattgc ttccataagt agtaaagtta tttttttatt
    26521 tattctaatt tctctgttaa tttcttcaaa atcattataa tccaaattac tatctacttc
    26581 agtgttaaaa ctatcatcta cttcaatcaa ttcaattata ttactttctt cagagtctat
    26641 aactttatct tcagtaatat tattgtacat atttttaaat tgtttttcta aaaattcata
    26701 ctcatatttt gaaatttcta aattagtcac ttcatttcct aaaatagtag aaaaaataca
    26761 attatttata ataagttcaa ataaatttac aagtatagca tcacaatcta ttttataagt
    26821 caccccatag tcataaaata atttttctct atcttttttc ttaaataggt tacaaaatct
    26881 attttctata tctatactct caatataatt cttcacataa taaataccct taacatccat
    26941 atcatctagt gccaatggat aatctatact tactggaacg tcctgagctt caaattttac
    27001 aatataactt ttaaagaaac ttgataactc catcaaggta tcattatatg ctattgaatt
    27061 agtatccaat tttctactca tcattagttt ataaaaatct tttagcctaa ctaactcttc
    27121 ctctaatatt tcaatgcctc caaggtacac ttttttaaca ttcttagcag tcaactccac
    27181 aactcttttt tctatatccc caagcttatt tatatatgca tcaatagcat accatattga
    27241 aatcaacagt ttttcggcaa cttctgtttt tactgatgtg ctttgaccat ttgtatattt
    27301 tttaatcaaa tccataagta ttagagatat ttcttgttgt atattatata cttctctttc
    27361 atctatcact ttacaattta gacattcctt aagtagagat atggaatatt ggttctttat
    27421 taaattattt tcgtttatat taatattact taaattattt aacatacaaa atctctccta
    27481 tcatatatta aacttctcca aatttaaatt tctttgcaaa ttcgtctgct tctcctctta
    27541 cattgtccat attgcctgaa aatttttcat aaaattcacc cagtatttct ataatctcat
    27601 catcacatat cttgtcatca gtttcatttt ttaaataata aaaaatttct tgcatatcat
    27661 taatagcctc taaataattg tccacatttg tatattgtga tgtatatata ttttctatta
    27721 actgttttgt aacttttata tctaattcta ttcttccata cccctttaaa gtattatctc
    27781 tcgaatttat tatatctttt acatcagatt cagaaagagc tagaccataa tctccagatt
    27841 ctatattagt ttcaagcagt tcatttcttt ctatttcctt taaattctga tttatagaac
    27901 tcaaaataat aggtgatatc atttttaaat tctccttttt tattttttcc attgactttt
    27961 tttgtttttt atgctatact taaattaatt tatattattt taccaaccac ttataatagt
    28021 agtgttaaaa gtggtttttg tcaactcaaa attactatct caattaaact tttcaatttt
    28081 ctcaacaaaa aaataccatc atttagatat ataactttct ataacaactt ttaattcagt
    28141 agttatttac taaaatctaa acaatgatat atttattaat tttatttatc ttttttggct
    28201 ctacttctac ttttctttac atttgagcaa tttctacaag aaggtgaaca gtattgagat
    28261 ttagaatttg taggaatata aattttacca cagtacttgc atttatttaa agaagaaggt
    28321 tcacttgtaa ttgcaaaggc atagatagtc tcaatagctg ttttcaaaga atcaaactcc
    28381 catgcaataa ttggtttatc taattggctt atagaaaatc ctatcttttg aggattaaac
    28441 cctccagaca taatagtaac actttcagtt aatagattag atgtattttt atatacacaa
    28501 atttgattaa aatgcttaca catatcttta gcaaaactta caatccaatc tagttgttca
    28561 gtgtagaact ttgaaaatac taaatctaaa atcaatggtc tctttccaaa aaactttgga
    28621 gattcttctc tctttgatac atctataccc cttctatact ttttaaaata cacatcttca
    28681 tcacttgcaa atggtataaa catgtttaca tattcatctg tactcaatat attctctttt
    28741 gtaatataat tcttttcaat catcagtact ctttcttctc caactatatc tctattatat
    28801 acacttgaat atattaaacc caataatcca tactttttta caaattcaag tacttctttc
    28861 tttagtttca tttcttttgt ctcttttgat atatcttgta atgcctcttg tcctatgcga
    28921 attatatcta ctattatatc atctgctaca tcaaatgggt tatacatggt aaacacagca
    28981 tcttctgttg gaactatata taattcatct tcttcagtaa ttttatattc ataatcacta
    29041 tacctaatcc aatcacttgc aaaattccct attaattcta tttttttatt cataataatc
    29101 attcacacct ttcaatgtaa tatataattt catattacta ttacactttt agtttattcc
    29161 atattttcta cactgtcaac tattcttttt atatttttag catattaaaa tttataatag
    29221 cctttataat ggatttctag agctaaattt cttgtttatt gatgactaat tcataattaa
    29281 atttataaaa actatttaca tataaaatta atctctttat aattgatatg taatatattt
    29341 ttacacttac atattacata tcaattataa agagaggtat ctaaaatcat ggatagaaaa
    29401 cgtgaattaa aacaattata caaagaaatg aaatttgaca caggtgtatt cataataaaa
    29461 aatgatatta ctaaaaagat ttaccttgga aaaagtaatg acataaaaag caaatttaac
    29521 tctctcaaat ttcagcttgg tgctggctca tgtatgataa aagaattaaa taatgaatgg
    29581 aaaaaatatg gtgaaaaagc atttacattt gaagttttag aacttataaa acatgatgat
    29641 aacaaaacag agaaagatta tttagaagaa ctagatattt tagagatggt ttggttagaa
    29701 aaattaaagg aagataatac ttatgaaatt tattccatat aaaaaatcat ataatataag
    29761 aaaaggagat agtatatcaa aatagacatt tagttcataa gatacttttt tatataaaat
    29821 aaagtatctt ttcataattt taacaatgaa aaagaggctt atctccattt gatagcctct
    29881 tcccatatat tttataccat tataaaatga acaatctact aattttcaat gtgtatattc
    29941 attttactaa taacactcca ttacttcttt acagcatcca aacattgctc tataatactc
    30001 ttatcactta tacctattgc tgttacttta ctagctccac ttaatatact cttatcactt
    30061 ttatttgaaa ctaaaacaac aggagcattt tttgcaagtg gtgatgcaac taaagcataa
    30121 actaaatcgt ctccacttgt tatatagaac tcttttgctc cattatagaa cttttcaata
    30181 acatttttat tagtttgata tctatcaaca ccaccaattc tagttgctct atatctgctc
    30241 actatgtaat cacttaatgt agactctcct ccaatagcat atactggaac aggagaaact
    30301 ccaaaccatg ggtctaagtc tgtgtcttct tctgctgaag gtatatcttt tgtcaatatt
    30361 ataggagctc catctctata agcaacagat gcaacactta ctgcatcagc ttcatcctta
    30421 aatccattta ctaaaaacat cttatcactg tttttaattt tttctatttc acctgcaatt
    30481 ttataacttg tatctactct atctacacca tcaattctta taacttgcat tcttctcata
    30541 agtaacattt tttctacatc tttacttata gaattttctc cacctattac atatatctta
    30601 gtaactctat tcagtctttg aagcgttgct tctggtatat catccttatt agttaataaa
    30661 atagctgcat tatttactcc tgcaagacca cttgcagcaa tcccatctac cattgtagaa
    30721 tctgcattga taagaactgc tgttgtaaaa tcttgcttat ctgaaataag cccagctgtt
    30781 tcatatttat ctactccttg aatattttca atcttatcta gtgcgtttat tgatgttgga
    30841 aaactaacac ttaacagtaa tgctgaaata cctaacgcca ataccttttt actaatcctc
    30901 ataaattacc tccctaaaac aaatatattt agtattagta taatataaaa tcatttaaaa
    30961 atagtgtaaa aatagttaca cttttttata atttaaataa ttttagatta aacacaattc
    31021 atccattaaa ataacttcat ttattctata tgctaagcca tcccacgttt tttttgacat
    31081 atctacagat gttttcttat ttgagttatt caataaagat tgtatcttag aatctattgc
    31141 attatacaaa ttattttcaa aatcatataa ctcttcatct tttggaatac cttctttctc
    31201 cataaaaggt agagaaacat attctatctt tccagaatta ttaatctcac taccaatcca
    31261 ctctttaaca ccaagaatat cagtagtgat tacatctgtg ccacaagata aagcttctaa
    31321 aactacaact ggtaatccct cataaaatga tggtaacaca aatatttgtg acctgttgaa
    31381 tagctcagct aaatctctct gttctaactt tcctaggaaa ttcattttaa atggagactt
    31441 acttgccagt ttaactatct cattatatga ttcgatatcg cttccagtac ctgcaaaatt
    31501 gacttctatt aaatctttac tatattttaa tttagatata gcttttataa atggaatcag
    31561 tccctttgat ttacatatct tacctgcaaa tactattttt attttatcat cctttatttt
    31621 ataattttta ttataaaata tatcatcatt ataaccacta ccaattacaa ctactttact
    31681 ttgacttact ccaaaagtct ttataatatc atatttctga ttttcatgaa gagcaaatat
    31741 taaatctaat ttccttatat ttgctattat gtattctttc tctaaatcaa tggtatttaa
    31801 ctgtcttaaa caagttccat gacaaataga cataaccttt atatctttta ccatttccct
    31861 aacaaatgca gttaaaaggt acaaatgatg acatattata agttctggtt taaaatcatt
    31921 catagcctta tctatattta ctttaaattg atatttcaat ctatttatca tgtctatatt
    31981 taaatcttta tatcttgtac tttcatatgg catagaatca ctcataccta caacaggaaa
    32041 atttaactcc ccacaattat actttactgg ataaaaactt acttcacttg gaaaacaatt
    32101 tacatcatca tttacatcta tacctgcaat tacagcttgc ttatgaccga ttttttcgaa
    32161 tccttttatc ataccagaca aatatatacc actacctgta ctatttggtt tttgtgttat
    32221 tatatgaaga attttcactt ttcacttgcc tcctttctaa aattaaatag ttttatacag
    32281 tctaatcatt atatatatct aaatataaac aagatgaatc atcttttact ttaaatcttg
    32341 gcactttaac cgctttatag tcattatctt caaaatccct tactttatta tgtatatatc
    32401 ctataccaaa tttttctgct atacgtatca attcttcttc ttttattaga ttatatctat
    32461 cacatgcact tgtaaaacca tcactcgtta gcatcaattg aaaatctttt tttatttcaa
    32521 tgtatccata tatagaattt tccacagctt cctcatcaaa atccaatatc caatagccct
    32581 cttttgtatt tttcttcaat ctattgctta ctattgtatc cataacacta gttctaatct
    32641 catcaaatgc catctcttcc aagttagaaa gtttactcat ttcatcaaat acagtattat
    32701 caaatttaca aatactccta tcttttataa ctttggaatc tccattttta ataaacaaag
    32761 cacaatctcc taataaaaaa tactctactt tattttcatg aaattttaca acaactatag
    32821 aactagatgg taaatctaat ttttcaacct taaacccatt taatcttagt tcatactctt
    32881 tttttacttc tattattcca gtattaataa tactctttaa tgattcttct ttatttatat
    32941 ttttatataa atacctattc caccactgaa cataccacct tgcgtcactt tcagttgaca
    33001 ctaaattttt tccattaagt cctgtagcac catctaaaac ccatgcccca aatggattta
    33061 taccgactac atcttcatta aatttagctg ttccttgatt acataatagg ctatagtttc
    33121 ttatatttaa agccatatca acctccaaat tgaatatcta aaaataaagt tctatttaaa
    33181 attatacagc aaataaaaaa atctacaaca aaacttgttg tagattttta cttaatctat
    33241 attatcttta tactttcagt attttaatga tggaataatc tattcttagt aaatgccatg
    33301 actatgttat acttattaca agttaatata acattatcat cacgaataga accacctggt
    33361 tgtgctataa aacttacccc acttcttttt gcacgttcta tattatctcc aaatgggaaa
    33421 aatgcatctg aaccaagtgc tactcctgtt aaagttttaa gccatgctct ttttccttct
    33481 ccagttagag gctctggttt ttcttcaaaa aagttttgcc atatgccatc agcaagcaca
    33541 tccatataat catcagaaag atatacatca atagtgttat ctctatctgg acgacctata
    33601 tcctttttaa attttaagtt taatacttta ggatgttgac gaagatacca agtatcagct
    33661 ttgttacctg caagtctagt acaatgaata cgtgattgtt gacctgcacc tacccctatt
    33721 acttgtccat ctttagcata acaaacagaa tttgattgtg tatattttaa tgtaataaga
    33781 gctataatta aatcacgttt tgcactatct gtaaaaattt tattatcagt tggaatatct
    33841 tttaataggt cttcatttat taatatttca tttctacctt gttcaaaagt aattccataa
    33901 acatcctttg tttcaatagg ttcaggagta taattttcat ctatttttac aatattatag
    33961 ttgcctttac gctttccttt taatatttca agggcttcat ctgtatatcc tggagctatt
    34021 ataccatcag aaacctctct tgctataata gttgcagtct ccttatcaca tacatctgaa
    34081 agtgctataa aatcgccata agaagacatt ctatctgctc ctcttgccat tgcataagca
    34141 caagctaatg gagaaagctc taaatcatca acaaaatata tttgctttaa agtatctgat
    34201 aaaggtaccc ctactgctgc tcctgctgga cttacatgtt taaatgaagt tgctgctgga
    34261 agacctgtag cttcttttaa ttccttcaca agttgccaac tattaaatgc atctaaaaaa
    34321 tttatgtatc caggttttcc atttaatacc tctataggaa gttctccatt cttcatataa
    34381 atctttgatg gtttttgatt tggattacag ccatacttta attctagttc tcttgccata
    34441 tactcatccc tctctataat aaattaatca taagtttgat taatcctata ttaattaaat
    34501 tattcgtact aataaaatta tatggcatat ttatccatta atcaactata ttttttaaaa
    34561 ctcctattcc ttcgacttta cattcaacta tatcgccatg ctttaaatat acttgaggat
    34621 tcatccccat agcaacccct gctggagttc cagttgaaat tatatctcct ggctttagag
    34681 tcattcctct tgataaatca tttattatag taggtatatc aaatataaag tactctgtat
    34741 tagaatcttg tcttacttct ccatttacta cactacttat atctaatttt aaaggatgtt
    34801 caaattcttc tttatgtact atacaaggtc ccatagatgt atgtgtgtct aagctttttc
    34861 ctctaaacca ttgaacatgt ttatcttgaa gtgctctttc acttatatca tttactattg
    34921 tatatccaaa tatatattca taagcatctt cttttgatat atttatacct tctttaccta
    34981 tgattactgc aagttctgat tcatagtcca acttctctac caaatctcca tgtaagctta
    35041 tcttatcatc cactccaatt attttgtctg ctctcttaga aaaataaatt ggataatctg
    35101 gcataactac gttttttata actccatctg ggatttcatt gacatggtct ttatagttta
    35161 gacctaaaca tataatatct tttttaggtc ttacaattgg ggaacataat ttaacttctt
    35221 ctaacttata acactttgcg ttttcaaatg aattgttttt tattttttct aaatctcctg
    35281 tagatacgtt ttcaataaaa tcattcatat cagtatataa tttacttaat cctaaactat
    35341 taatttcata tatactattt gtttctgaat taaatacacc tattttttct tcattgctac
    35401 tacaaaaagt cacaaatttc atttttattc ctccattcaa taagttgatt aatattattt
    35461 aatttttatt agtttatata aattgtaatt cataatattt atatgtcaat acatatttat
    35521 atattttaaa aatattcaaa taatttttat taaatttatt agttattaat atataagtgc
    35581 tttataaaac acaaataaaa taaggttgat ttaaaattaa atttaaaaca accttataaa
    35641 ccgattatac tatctaccta ataaatatag caaataagct cctcaataat atacaaaacc
    35701 ctacatctct aaacctatac ttaactaatc caagtacaat accaaaaaca gtacctatca
    35761 taatttttga aataataact tcaaaggtgt agcttgaatt gttatacaat attacataat
    35821 ttcttataac atctatgtat cctatattat aaattccaga tagtatagat gttatacaga
    35881 taattttact ctttgacttt ataaaattac ttagatagtt ccatatatat tctctaaaaa
    35941 ataactcttc aaatattggg actatcaata cagacaaagt catcatagtt acattaaaaa
    36001 gtacatatcc cttagtacaa taagttacaa ttattgctaa agataaaacc acaacaaaaa
    36061 gtatcagctt acacttttca ataagtatat tgtttttatt ttcttcaaaa gcttctgtga
    36121 tttttctatt tctaaccttg ttatacaaag aattatcttt taaaaataaa attaacgata
    36181 aaccaactaa tgtaaaagaa attaagttta taatattaaa attttcaaga gtaaattcaa
    36241 attgacttag aagtacataa ttcaaaatca tccttaatat ttgaactata aacatcaata
    36301 aaatagaatc tattatgcat tttttgtaac tatacttcat cccaatttaa atcaccccat
    36361 gtatatgcta atcgtaaagt ccatttaata ccctacttac agttgctttg ctccaacttg
    36421 tttgatttga aatttcttta tagcttaagc catctcttct taaactcttt atattattta
    36481 tatcatcatc agtaatttgt ttttcttttg gcttaaggct atttttatag cttcttagtc
    36541 tatccaattc tgatttcaaa ctatctacct caaactgttt tttttgaagt ttactctcat
    36601 aagaatctct catttcatta aactctttaa tgtagtttac tttccagtcc tcatccattt
    36661 ttgttttaaa tatacccata ctttaacctc cttaaatttt gttactcaag ttatgtatcg
    36721 attataaaca ttaatttcta tatttatctt taaaatcctt gtacataacc cctagataag
    36781 ttagtaaaat tcagatatat ttttacaatt ttaagtatat attaacaata gaaaaaaata
    36841 taatgtctta atacaacata ttatatacta aaagttgtta aaatgaacct ttttatagtc
    36901 taaatcagag tcaccgtatg ctttcttttc ttcatcagga tatcctatag aaattataca
    36961 ttctacactg tacttgctag gtacttttaa ttcttctcta atgtacttat cagcttctat
    37021 attatcatca tgcattctat ttcttacttg tatccaacaa gaacctaaac ctagttcatg
    37081 agcttgaagt tgtatgtatg aagcagctat acttgcatcc tctatccaaa catcattttt
    37141 ttctttatct gcaataatta caatagctaa aggtgcattt tttaagaaaa atccaccacc
    37201 tttagttcta cattgagata aattaattag cttttcttta tcatctacca ctataaattc
    37261 ccatgttcta agcccctttg atgatggagc taaaagagca gcttttaata ttttatctaa
    37321 tttttctttt tctacttcaa catccttgta ttttctaata cttcttcttt tctttagaaa
    37381 tccaatcata taaatcatcc ctttcataat agcatacact aggttatatt atgcccttac
    37441 taatgctgaa aatctattat ttatcccttg tattataaat gctctttata atattttatc
    37501 ataacagtag aaagatttct cctttcctaa aaaactcatt tctccgattt ttataaaacc
    37561 acactttgta agtaataaat tcatttttga gtttattgaa tatgtatcgc tctttaagta
    37621 tgatacattg ttttctacag ctaatttttc agcaaaatca actaacttag atgctattcc
    37681 tgtctttcta aagtttggat ttacagccat tctatgtatt accattgctt ttttattaga
    37741 tgaccaattt aagcctaaat attcttctgg ctcttcataa ttaagacata taaaccctgc
    37801 tacttctcca tccacttcat aaatatataa atcttgtttc ttaatatctg aaacaaagtc
    37861 tttttctaat ggatagtttt catcccattg tgtattatta taagtcttca tttcttccac
    37921 tgtagatttt ataatttgca taatgctttc taaatcattc atattcgctt ttctaatcat
    37981 aaaaatatct ccttaagtta atgtatttat ttactatctc tttactttaa accattcatt
    38041 ttctacgttt ttgctcattt tttctaataa cttagttacc acttgttttt cttcatctgt
    38101 aaaattatca aaacatatct ctatacttct attctcttct tcaattatca actcataaac
    38161 ttccaaagat ttatcagttg gagttaaatt atatcctctt ttatcaaact tatcctgctt
    38221 tttatctaca tatcctgcct ttattaattt ttgtatagcc ttggttgttg tagccttgtc
    38281 tacctttaac atatttgata attccacaag atttatacca ggattttcac agattcttgt
    38341 caaaaatgta aattgtcctt tttgtaactt taattccttg tacttaatat catttattga
    38401 atttactgct ctagataaag tacctacttc tcttaatata ttactatcta aagtcttaat
    38461 caaacacacc tccactgaaa ctactatggc taaagtcaaa tagtttctgt tttataaaat
    38521 ttcacataat caatatattc atttttagtt gaaagttcaa cttttttaaa ttttaccata
    38581 ttttggttga aagttcaatt aaaaataata aatttattta atctttcttt gcatattaat
    38641 caattaattt taaaattaaa atggatatcc caaaattaac tttttcgttt atgaggaact
    38701 ctcttttgta taaaatcaaa tatattttat cattccaata aaaaaggctt atctctattt
    38761 tgagaaagcc tctttccttc aatctatatt ttactttttc cctaaataaa atctatacaa
    38821 tatacttaca cacctcatcc gcaaactctg tagtagaagc tgagccaccc aaatctacag
    38881 tcaatttact tccttcaaga aatacttttt ctaaagctgt ttctattttt tgtgcatttt
    38941 catattcacc taagtatcta agcatcatta ctgatgattg aataagtgct gttggattag
    39001 ccttattttg acctgctatt tgtggagcac ttccatgaac agcttcaaat atcgcacaat
    39061 ctttaccaat atttgcactt ggaattatac ctaaacctcc aacaagccca gcacctaaat
    39121 ctgatagtat atctccataa agatttggca ttaccattac atcataattt tctggattta
    39181 aaactaagtt catagctgct gcatctacaa tcaaatcatc atattctaca ccatgttttg
    39241 atgcaacttc tctaaacaca tctaaaaaca atccatcaga cattttcatt atatttgcct
    39301 tatgtatagc tgtaactttt tttctcttat tatctttaac atagttacat gcaaaatcaa
    39361 cgattctttc acttgcactt cttgttatta tctttatact ttcagctgca taatcaccta
    39421 ttttatgttc tattccagca tataaatctt ctgtattttc tcttacaacc actaaatcaa
    39481 catcttcata tcttgatttt atccccttaa aacttttaat aggtcttaaa ttgacataca
    39541 aatctaatgc ctgtcttaaa gttacattta cactcctaaa tcctttacct acaggagtag
    39601 taattgggcc ttttatagct attttgttct tttttatact atctataata tattcaggaa
    39661 gtggagtacc atactcttca ataactgcct ctcctgcatt aacttcttcc cattctattt
    39721 ctactccagt agcttctact acctttttca tagctttcgc aacttctggt cctattccat
    39781 ctcctggtat aagtgtcact ttatacattc aatattccct cttttcatat taattagctt
    39841 gatttttagt gtagtttaat tttccaccag cttttaatac atcaacttct tttgctgaca
    39901 attctacttt gaccttaaaa gaagttcctt tagttgtatt cttaacttct aaaattccac
    39961 tacctagatt gtctaaaata tttggtatct ccagattatc taaaagagat atattttcat
    40021 aatctttctc atcacaaaac tccattggaa ttataccact atttatcaag ttagccttgt
    40081 ggattcttgc aaagctctta actattaccc ctttaacacc tagatataat ggtgctaaag
    40141 ctgcatgttc tctacttgaa ccttgaccat aattatctcc accaactata aatccaccat
    40201 tattgtcttt tgctctctga ggaaattctg tatctacagt attgaaacaa tagtttgcaa
    40261 gatacggtat attacttcta aaaggaagta acttagcatt tgatggcatt atatggtcag
    40321 tagttatatt atcttctgtc tttaatataa cttttccacc tatagactga cttagctctg
    40381 tattaagagg gaaaggtttt atattaggtc ctctaactac ttctacatca cttcctacat
    40441 cagcaggttt aattatcatg ctatcatcta tcaaaaattc atttacatct aaatttgtaa
    40501 atttaatatc aaattctctt gggtctgtaa gcactccctt gattgcactt actgctgcca
    40561 cttctggact tactaaatat acttgtgctg acaaagtccc acttctacca tagaaatttc
    40621 tattgaaagt tcttaaagac acagagtcag tacctggaga ttgacccata ccaatacatg
    40681 gaccacaaga attttctagt attctagctc cagcacttat tatatctgcc aaagccccat
    40741 ttctagcaat catctccata acttgtcttg aacctggtgc tattaccaaa ctcacatcct
    40801 tatgtacttt atttcctttc aggatttgtg ctactttcat taagtcttca taagaagaat
    40861 ttgtacaact tcctattgcc acttggtcta ttttaatctt gcctatattt tcaacttcat
    40921 ctacattgtc tgggctatga ggttttgcag ctaatggttt taattcatcc aagtttatag
    40981 taatctcttc atcataaact gcatctgcat ctggttttag ctctatccat gcctcttctc
    41041 ttccttgact cttaaaaaat tctagtgttt tttcatcact tgggaagatt gaagtagttg
    41101 ctccaagttc agcccccata tttgttattg tagctctttg tggaacagat aggcttttga
    41161 caccttctcc accatattca taaactttac ctactccacc ttttacagtt tgttttctta
    41221 acacttctaa tattatatct tttgatgata ccatattatt taattttcca actagattca
    41281 ccttacagac ttttggtgct tttatatagt atgctcctcc tgccatggct aaagcaacat
    41341 ctaatccacc agctccaata gccatcatgc ccacacctcc agcagtaggt gtgtggctat
    41401 cagaacctaa aagtgtatct cctggtgttg aaaatctttc taaaaatact tgatgacaaa
    41461 taccatttcc tggcttagag aaataaactc catatttatc tgccactgtt tgtatatact
    41521 tatggtcgtc tgcattttca aatccttgtt gtaacatatt atggtctaca aatgccacac
    41581 ttcttttagt ctttacttta tctattccca tagcttctag ttgaagatat gtcattgttc
    41641 cagtagaatc ttgtgttaaa gtttggtcta tttttatacc aattgaactt ccagcaacag
    41701 cttctccatc tactatatgt tttttaatta ttttataaac tatattatct cccatatttt
    41761 cctcctaaac aattatatct taaatatatg aacctctaac tgcttcttct tctgttgtgc
    41821 ctttctcatg tgctagtata tcacaatata attgaagaat ttctttatcc attaaacttc
    41881 tttttaatct tatagatgta gctcttatag catttaatag cttggtagcg ttttctggag
    41941 aaatatacat ttcatattca ctcaacttat ttacaactgc agctcttcct gaatgtttac
    42001 ctattactat ttttctttca agatttactt cacttgggtc aaatggttca tagttatgtg
    42061 ggtcttttaa agctccatct gcatgtatac cagattcatg tataaacata ttatccccaa
    42121 ctactggttt ccatgtagga agtattcttc ctgatgcctg tgctacatac tcacatattc
    42181 ctctaaattt tctagtatct atattattta aatcacattt ataaacacac ttaagtgcca
    42241 ttaaaacttc ttctaatgct gcatttcctg ctctttcacc taatccattt actgtaacac
    42301 caacataatt tgctcctgct gctattcctg caagtgcatt tgcagttgcc atcccaaagt
    42361 cattatgtgt atgcatttct atatcaaaat tagttctttc ataaagagtt tctattgcat
    42421 tctttataga aaaaggattc ataactccta ctgtatcaca gtatctaaat ctatctgccc
    42481 ctgcttgttt tccaacattt ataaattcag ttaagaagtc tatatctgct cttgaagcat
    42541 cttctccatt tactgaaaca tataatccat ttttctttgc aaattcaact gttttagcca
    42601 tattttctaa aacccagcct ctagaagttc tcaatttatt ttctatatga atgtcagata
    42661 ctgatattga tatagctact gcatcaacac cacaagaaat agattcttca acatctttta
    42721 ttactgctct attccaagcc attatatctg attttaaatt tctactacat atgtgcttta
    42781 ttacattttt ttcatctcca cccatagtag gtataccaac ttcaatttgg tcaacaccta
    42841 ggtcacttaa catttcagca atcattattt tttctctatt tgcaaataca accccagctg
    42901 tttgctctcc atctcttaaa gtagtatcta ctatttttat ttcctttgct ctatcttttg
    42961 atataacgca catattaatg ccccccttag tatactttta attttaaaac attaagtctt
    43021 atttttcatt gatacctcta acttatgatt atttttttat tttttattca ttttaatttc
    43081 atttgcaatt tattttttta gcttttcata tcttgtaatc tattatatta ctttgtatca
    43141 tttattgcac tatatttttt cttttttgtg aaaacttctt aaaaatgaaa gttattatgt
    43201 ttttcttgca ttttaattta atttttaaat agatttattt tcaaaaaacc tttaaaaata
    43261 aacctataaa attcctacta aaatttaatt taagttacat tccattttaa agtatcttaa
    43321 tatattttta agctatataa ataataatta aaaaatttac taaaaatact tataaatatg
    43381 atattattaa ttggttaata aaaaagaaaa tttttcatga aaggtaagat aacaatggat
    43441 ttcaaaagct tagggattag tgaaaataca ataaatattc taaaaaaatc aggaataaca
    43501 acacctacac ctatacaaaa agaaagtatt aaactaataa aagaaggaaa agatgtaata
    43561 gcagaagctc aaactggaac aggaaaaaca ctagcttttt tacttccgat atttgaaaat
    43621 atatcattag atataaatga tatacaagta cttatacttt ctcctacaag agaactagct
    43681 attcaaataa cagaagaagc tatgaaactt aaagaatcta aagatgtaag tattcttgca
    43741 gcatatggag gaaaagatat tggttctcaa ataaagaaac taaaaggaaa tattcatatg
    43801 attatagcta caccaggtag gcttttagac catctaaata gaaaaacaat agaccttagt
    43861 aagttaaaga cttttgtttt agatgaagca gaccaaatgt tgcttatggg atttaaaaat
    43921 gaagtggaag ctattttaaa agagacttca aacaaaaagc aaacactatg cttttctgca
    43981 actataaatt ctcaagtaaa aaaattagct tatagataca caaaaaatcc tgttgtagtt
    44041 tctattcaaa aagaagaaat cactcttaat aatataaaac aagaagtagt agaaactaca
    44101 gatagaaaaa aattagatgc cttatgtaag gtactagatg aagataatcc ttttatggca
    44161 ataatatttt gtagaactaa gagaagggtt gacaatcttg aagaagctct tgctataaga
    44221 ggatataatt gtcaaaaact tcatagtgat attgctcaat caaaacgaga aagaataatg
    44281 aaatcattta gaaatttaga tatacaatac ttaatagcta cagatgtagc ttctcgtggt
    44341 cttgatatat ctggagtaag tcatatatat aattacgatt taccagaaac accagaagac
    44401 tacatccacc gtattggtag aactggtaga gctggtgaag aaggctatac atgtgctttt
    44461 attgacccta aaaatgaacg aatgttaagt gaaatagaga cggctataga atctaaaatt
    44521 agtagaagaa ttatagaatt ataatttata gattgcttaa aataccaatg ccacacaaac
    44581 actgtaatat atagaaagct acagaaaaca tgtatcaatc tatactttgc tgttatacta
    44641 ttttatatta aagaaaaaag aggctatcca aagtaggatt agtctctttt attgtcaaaa
    44701 taatgaaaat atatttgact tcatataaaa aagagtgcct tataaactaa aagtccattt
    44761 tgagacaccc tctttttatc ttttattctt agttttatat tgcttgttta tagttgttta
    44821 atattagatt ttgcaaataa tcttaataaa catgcagata tattatctat agtattctta
    44881 tctatagtat tctctttagc aatatttttt gctactacat ctaatttaca ttttcattta
    44941 attccgctgg ccatttagct tctggatttt cctttgcaaa cttcttattc ttataatgtc
    45001 ctagtgtaag gaatggaatt actatagtga atagaccaag ataaccacaa tatccatatc
    45061 catatttaac aatattactt aatcctgtaa gtgatataag cattgacact accattattg
    45121 cacaagctgt aaataccctt cttttcattc ttgaagaaag gaaagaaagt gctttatggt
    45181 cttcaaatct atttacaaga ccaaatatag tagttactcc tgtagacatt aaacaaagga
    45241 ataatgcaac attataaatt atgtatatag tatgatttcc agattgacct gcaacataaa
    45301 gagtagggag tgttgtttgc ccagcagcaa taatttctct ataccatccc attagcatag
    45361 ttacagcaag tcctaatgca attgcattca taacaaatga aattatcatt gccttagtag
    45421 cttcttttga gttcttaaga agtggtcttg aacatcctgc aagtgtaggt ataacaaccg
    45481 attgaaaacc tgcataaata aaagtattaa gtattggctt gatatagcca ggtgtgaaac
    45541 tcgttctatt tgataatatt tcagttattt ctggtacttt agcttttata ccaacaataa
    45601 aaatagtaag agtacatact agaatagcta ttgtcattgc tgtagctgct ttagatacaa
    45661 gcatagcacc aaatatagta aagacaagaa gtacaactcc aataataaat acagctacaa
    45721 aataatttac tcctatactt tgaaatactg ctgctgcacc tgctataaca gcacttacag
    45781 ctattaaaac cattagatag taatatatct cccatattat ttcaagtttt ggatatggtc
    45841 tccaaagctc acaaaataaa tccttataat tcctacaatt gttattatta tacattatga
    45901 taacttctct catggtagca gtaagtataa tcattgctaa aattgccata agtggtgctg
    45961 tccatccata ctgcacatag tactgagttt cttgattccc tgtagcaaat cctcctcctg
    46021 catgtgaact aaaaagaacg cttgcaacac caaaaatggc taacatagag cccgttactt
    46081 ttgctttctt tacacttttt tgcatgaaat catcctccct aaaatgatat taaaagtttt
    46141 tattttaaca ctttattgat aaaacaataa catttttgct cattaaattc aactatattt
    46201 ttccaatgac tttacatttt caacttattt ctacctttat attaaatatt ttttatatat
    46261 ttattttatt ttttaaatag tattcaaatt cactttgttt tttaatttta tgaaatatct
    46321 tttttaatgt taaatattat acattttttc tttattatta tataattttt tctttattat
    46381 tttataataa taatagtata gtataaaatt ccttctttta ttacattcat tggaattatc
    46441 aaactttaaa agaataaatc aatatatttt gtgaaaaaat atactgtaat gtaagtaact
    46501 ttgatttatt tatatttatt ctaacattat taatacataa taaaattgtt tattaatgaa
    46561 aatatattct cattaaaaat aaattttttt acaatatttc atataaaagt atattgattt
    46621 ctcttaaaat aaacgtaaca aaaaagatat tttctataga aaatatcttt ttaaccttca
    46681 acttaaatct tatatacttt caaatactat atacttatgg tcagccctac tccaacttca
    46741 tttatattca atatttcatt catcttcgct tttaccttaa aagaaacaca gtgacaaggg
    46801 tacaacattc ttatttcttc tttatccaaa tattgtattg tactatctaa cctattattc
    46861 aattcaaaaa gatgaaaacc acctagtata ccaataactc tatcatctcc acataccttt
    46921 ttagcatact ctactatatt acaaattcca ctatgagaac atcctgtaac aataaaaata
    46981 cctttatcag ttttacaaac tatagcagaa tcatctaaaa cataatcatc ttcccacaaa
    47041 tctcctattt tacatttacc aattttagct cttttttcaa aatcatttat agaaggtatt
    47101 tcacctaaaa acacacaatt cttgcttaga ttaaatggct tatccttagg attatacata
    47161 aaaatatttt taatttcctc agcagaaaat ggagctccta tgcttttctc tccatgtttt
    47221 ctaggtataa aacagttagg atgtgaaata agttcaactg tagataaatc atacctattt
    47281 tctaaaaact ggatacctct tgtatggtca ttatgcccat gagaaaaaac aacatgagtt
    47341 aaatttccta aatctatatt taatttttca gcgtttgata tgaatacatc tgaataccct
    47401 gagtcaaaca aaatcctatt tccatcaatc tcaatataat agcttactgc tggttctcca
    47461 acaaagtatc tatcaatata agtattattg tcgactaaaa cttgtatctt caatctttcc
    47521 ataataatca ctccttaaat ttttatttac tttaaagtat agaatcttta gtttaatagt
    47581 acgacatcac agaatatttt acaatttaat atctttaatt ttcataaata gaaggagtct
    47641 atctcaaaat aaagagataa gattcttttt cattgctaaa atgataaata tatttggctt
    47701 catacaaaaa agagtgactt atgaactaaa aagttcattt taagacactc tcttttataa
    47761 aatatattta tcatttactt ttatagctat ctaaaatcta atagtttcaa acttcaatct
    47821 atacatgctg tatgtttgta taatttgata cttcagagtt aacagtatat aaatcatcaa
    47881 cacttaaatc atgtatatct ttatgaccag aaattctagc aaaagtctta agttcttcta
    47941 aacttacatt taaaaagttt gccactctat tagcactatt ttctatatgt aatctttttc
    48001 tcaattcctc atcctgagta gctactccta caggacactt accagaacca catatacgat
    48061 attgttgaca cgccgctgcc ataagagcag aacttgcaat agcaactgca tcagccccca
    48121 tagcaattgc cttagcaaaa tcagtagata tacgaagccc acctgttata accaaatcta
    48181 tatctaatcc atgtgtatct atgtattttc tagcacgata aagagcaaat attgttggaa
    48241 ttgaagttgc atctttaagc aactttggac ttgctccagt agctccacca cgaccatcaa
    48301 tagttacaaa atcaggttta gcataagcta taaattccat atctttttca atatgacctg
    48361 ctgaaatttt aacacctatt ggacgccctt ctgaaacttc tctaagttca tctacaagtt
    48421 tctttaaatc ttctttggat tgtatttcct caaaacaaga tggacttatt acatcttgac
    48481 ctacaggctt atttcttact tttgctattt cttcagttac tttttcgcca ggaagatgac
    48541 ctcccatacc aggttttgtt ccttgaccaa tttttatctc tatagcatca gaatttttaa
    48601 gattttcttc agttacacta tatttatttg gtacatactc aaaaatatac ttgtatgaag
    48661 cttccttctc ttctggtaat atacctcctt caccactaca catagctgtc ttattttggg
    48721 ctgccccctt tgctaaagct atttttagtt ctttagacaa agctccaaat gacatgtggg
    48781 aaatataaac tggattttct ataatcatag gtttctttgc tttttttcct attattgttg
    48841 ttgtatttac ttcatcatgc tcatttaaag gtaatggatt taattgagca cccataatta
    48901 aaatatcatc ccaagaaatt actggtagtt tagttctcat aggttctatt atagattttc
    48961 ctgtaacagc catttcgtga attatatcca tatgtttctc aacttcatca tctcttctta
    49021 aatatgtact taagtaattt aaatctccct ctttttcagt atttaattta gattcatctt
    49081 caactatgtc ttctgctatc ttttcatctt cttcatagta aacagtactt atctttccaa
    49141 aataactacg accttttgta catacagggc attcccaatc ttcacttaat tcatcccatg
    49201 ttttatcatt cttagattca tcataaatat atccacaaac actacattta taaattgaca
    49261 tattattttc tccttatatt atattgacat taaacaaaat taaaacttga atttatataa
    49321 atttatagga ggctatttgt atgaaaatac atttatagcc tcctttttga ctcaatttat
    49381 ttaaatatta cagttcagcc ttccataatc catgtaaatt acagtaagca taggcagaaa
    49441 tcactttatc atcatcattc aaagcaaatt taactacagg ttctccatct actgctagac
    49501 atttgcgttg accaccttgt tcagtcataa gatacaccca tgctatatga tgttctttag
    49561 ttattggatg agttgtgcta cttactttaa cagtaacatt atttccatcc acttcaatta
    49621 caggtacatg tttttcaact gctgcatctg ttgtattagg aacaagttcc ttcataggtt
    49681 ttccacaaca gaaaataggt acaccaccac tttgtatcat tcctacaagg tttccacaag
    49741 tctcacatat aaaaaatttt tgttcactac acataaactc acctcattaa ttatttttag
    49801 aatttgaaaa ttaacctact tggctacacc ttttacaatt attacaaatc cctttaaaac
    49861 ttatgttata agatgttatt tttatgtctg tctcctcaga tattaattct tgtaaattat
    49921 taagaacttc ggattctaaa tcgtatacct ctccacatac ttcacatatg atatgatagt
    49981 gattatctat tcgaccatca aatctatctg gataccctgg aatactaacc tttcttataa
    50041 agccatgttc cgttagctga gctaaatttc tatacacagt tcctaagctt aaatttggat
    50101 tatctttttt taagttttca tataggtaat ccgcagtagg atgaaccgga ttatttaata
    50161 tttcatttaa aatcagttct cgttgtttag aaaatttcat agttaacatt cctttttaat
    50221 aatgataatt tttaataatt ttcagctttt atattaaaat atgcttttgg atggtcacat
    50281 actgggcatt tttctggtgc ttcagtacct acatacacat gaccacagtt ttgacattgc
    50341 caaacaactt cttcatctct tttaaatatt tttccttcat ttaagttttc taaaagcttt
    50401 aagtatcttt cttcatgctc tttctctatt tttccaacag cttcaaataa ataagctatc
    50461 ttgtcaaatc cttcttctct agcttcttta gcaaattttg catacatatc agtccattca
    50521 tagttttcac ctgctgctgc atcctttaaa ttttcctctg ttgaaggcat accatcatgt
    50581 aaaagtttaa accataattt agcatgttcc ttttcattgt tagcagtttc ttcaaatata
    50641 gcagctattt gattataacc ttcttttctt gcttttgaag cgtagtatgt atatttattt
    50701 cttgcttctg actctcctgc aaatcctgca attaaattct tttctgtttt agttcctttt
    50761 aagttcataa ttaattcctc cctttttaat aatagtaatg attactattt ctatatttat
    50821 atattatatc atttgccaat ttttgtcaac tatatataat attatttttt ttatttaaat
    50881 attcctattt tcaaatatat tatttaaaac atatatttta gaatatactt aatgtaatat
    50941 ataaaacaca tatgacagta ctctctcttg tcgctatacc tattgcaagt attatgatag
    51001 tcgtgattta ataaatacaa aaagaagcta cagttatgaa aaatcaaaac tgtagcttct
    51061 tgaatacatg agcatatagc cactgtacga cagatttttt cttttcactg tctagcaact
    51121 taaataatag aaacaatatt tatgttattt atgagaatac tttttatgct ttatcccttt
    51181 tttcttagat atggtcataa ctttatcata attaggtgta aatacaagta gaatagttgt
    51241 caagattaga attacaatca aagtcatagc accgataagt ggctgataaa cagtaccagc
    51301 accattgttg tatccaacta gaccaagacc tgctgtgatt ggataaaagt ctgtcagatt
    51361 tcttccagca acaaacacac cacaaaaacc gtatacaaat gcaatcccta cacccgtcag
    51421 aaatgcattt tgtttacgac caaaataagc aataatcggc aaaacagcaa cataacaata
    51481 cagattaata gacaaaatct gaactaagga ttttacaacg agtgtaacag atatattgat
    51541 attacaaaat aacaacccca aaataaatgt gcataagaag ctgaaaagac ttaacaatac
    51601 agtaattcct ccaaccgcaa ttaattttcc cactagcaat ttgcgtaatg aaataggaac
    51661 agttaggatg ttttttaagg tttggtctgt atattcacgg ttaataagat atcctccaat
    51721 aagtgtaatc ccaaatggaa aactaagact gaaattattc cagataactc cgtttgcaaa
    51781 gctctcatac gttagagggt cactgccgtg tgaacttaca acctgaaaaa ctgccaatag
    51841 tgctgaaaac agaacagcaa caacaccaat ccatagaata ttatatcttt ttattttttg
    51901 aaattctgta gtaattatat caagcataga tacctcctaa ttctcctgct ttttgtatat
    51961 catacaaatc agcaggactg ctataatggt tatcaaacat aaaataccta cacaagcagg
    52021 agttgagagc aaatatggct gtctaagtgc cgtgtattcg ccagtgggat ctccccaaaa
    52081 tgccatccac caacgcatta taacaggagc aggtaataca cttaatattg ggttatttgg
    52141 ttcaaaattg ataatattta aggatatact aaaattgaaa atagcatata caaaagaaag
    52201 tataatagaa aaaatatagc tgcgattgaa atatacaatg agtaccacaa caggaagtac
    52261 agtaacaaaa aacataattc caaaagcaat gctcattcct aattttacag caaccccctc
    52321 tactattcca acaatgaaac ctccaatgat agtagctcct aaccctgcaa cagagtagaa
    52381 caatgatata aacagcaaca cagccaattt tgccagagcc agttttcctt tttgcactgg
    52441 cactgttgca agatttttta atacatcatt atctctttct ataaaaaata gttggctagc
    52501 aacaatactt aatacaattg gtaatagcaa aaaatatcca aaattgacaa ctaatttgaa
    52561 caattgctca aatggcaagt tgtcctttgc aatcaaaatt gttgcgggaa ttggaaataa
    52621 gcaagcacct aaaatagaaa tcagtataaa ttttaaccgc ttgagttttg aaaattcaca
    52681 tgaaattata tcaagcaatt ccttcacccc ctgttacttt cttgaagtaa tcttcaagag
    52741 tatcttcgca taaatgagat tctgatacct caatgttgtt tagaatgaaa gcacgattta
    52801 tttctgcaac agaaacatct gtatcatata gcataatatt gtaattatct gctactttga
    52861 aatttttcag gttaagttgg gtttccagaa gccttgctgc ctgtgctgca tcagatacag
    52921 caaaatgtat gtatttactg tttttttctt ctaattgggc aagactttct tcctccaaca
    52981 aaataccatg gtcaataatg ccaatgtcat ctgccaacaa ggcaatttca gaaagaatgt
    53041 gactggaaat caaaatagtt ttacctcgtt ctgtgcagag atcacgaata aacgttctta
    53101 cttctgcaat accaatagga tcaagtccat tgataggctc gtccaaaatc aacagttgtg
    53161 ggtcatgcat aatggcaaga gcaatcgcca acctctgttt cataccaaga gagtattgag
    53221 aaaataactt tttgtcattg tttggcaaac cgactacatc cagtgctgat tctactgcat
    53281 ttttttttgg tattcctcta agccttgcaa agattttgag attttctgtt cctgtcagat
    53341 taggataaaa ccctggtgat tcaatcaaac atccaattcg aggaagaagc ttcttctcgt
    53401 tattgtgaat gtcctgacca aatattttaa tttctccagt agttggtttt gttagaccca
    53461 ataacatttt catagttgtc gtcttacccg caccgtttct tcctagcaat ccgtaaatgc
    53521 gacctttctg aacgtgaata ttcaaattag aaacgctctt ttgagcacca tattgcttag
    53581 tgagattttt tgtttcaata attaaattat tcataaataa taaaagcctc ctttgtttat
    53641 taaagttatc ataccacctc aatcttacat taaccttgca acaaccttgt attaaccttg
    53701 caactttata acttacaaaa aatccccctg tgtatacatg tcacatgggg gaaaaacaat
    53761 tttatattaa tggtaagctc actgtaaata tggtatactt tccaatctca ctttctacgg
    53821 aaatctgacc acccattcgc tccaccattt gactgacaat agatagacca agaccacttc
    53881 ctttttctga acgtccttta tcacacttat acagtcgctc aaaaatatgt ggtaaatttt
    53941 ctctggcaat cccaacacca tcatcctcaa cacggagtaa taccattctg gaatcctcac
    54001 tcatggtaat tttgatttgc cgagccttac tgtgagcaag aacattttga accagattat
    54061 tgaccacacg ggaatatcca tctcggtcga ggtttaccat tagtcgattt tctggaatat
    54121 caatttcaaa attcagtttc ttttcatgga atataggaat ccagtctttc aaaatattgc
    54181 gtgacaactc tgcaatttcc acagattcta ttgacagcgt aaattcatca gagttcaacc
    54241 gaaaccagtc aaaaagaaca tcaatgtaat ccttgaggtc gtaggctcta cgcctagcga
    54301 tttcaaggta ttcctcccgc tcttgttcga taactatacc actgtgtaca gcatccagat
    54361 aaccaatcag agttgttaat ggtgtacgaa catcatgaga taaacttgtc ataagttgtt
    54421 tgctagcttt atccgacttt ttcagagaaa gtaacttatt ttcataatcg tagacaatct
    54481 cattaagctg ataaaccaat ggagccataa catcatatgg cttaattagt attttacgat
    54541 tttcgtctcc aatttgtaca tcagccagta tctcctctat atcttttagg cgcttgtaaa
    54601 tatgcccaag cttggaaaaa gcaaatatgg aaagaaaaag tagaccaatc gacagcaaga
    54661 gtaagaaaag aattatcgtt tgttcatcca ttttcatacc tccgtgttga attgataccc
    54721 aattcctttt attgtttgca aatagatggg agatgatggg tctagttcaa tttttttcct
    54781 taggcgactg ataatagcca tgatattgct gtcatcatat acatatggct caccccacac
    54841 ggcttcataa atctgctgtt ttgtcaaaat cttaccctga tgccttgcac agtaaagaag
    54901 tacaccaaat tccttgggtg gaagcaacat aggttcgcca ttggtagtca ctgtatgctg
    54961 gtcaaggtca atcaacaaac ctttgaaaga aagttgctgt ggttcctcat tttttggatt
    55021 aaaacgggtg taacgtcgga ttaaagacag tacacgagca gtaaattctg taatttcaaa
    55081 tggtttggtt agatagtcat ctgcaccagc tcgcaatcca tgcactttgc tgtaattatc
    55141 gctttttgat gtcagcatta agatgggaat actgctatat tttcgtattt gttccatagt
    55201 ttcaaaacca tccatacctg gcatcatcac gtctagaact actaactgat aatcttgttt
    55261 tgaaagttca accagtccat ctctcccaga atggcaatag tttgcttcaa tctgttcaat
    55321 tgagatactc ttttttaaca aaatacaaag atctttatca tcatctataa ttaaaacttt
    55381 attcatctta gttccccttt ctacactcat tcgtagactt ttttatcact aggaatttag
    55441 tcatattgta gtatcttgac atcacttaga atatgctcct caatgaaata gtagtttatc
    55501 atatgaggat ttatacctca tttatcactt gcttcttcaa gtgtaatgct attcttatac
    55561 ttataacacc cattagtata tttcatcatt gtgaaaaaat caagcgtatt ataagtgtgc
    55621 ttgaataaaa caaacatgat aatacattta ctatatacag agttgaagaa tttattaaat
    55681 caaaacatca caataaaaca tatgtgaaat aagcaatcat tccagaaaat attttaaagt
    55741 atctttggaa ctattcctat aagtccagaa taaatttagg gttaactcaa aggtttattt
    55801 caattaacat actgcaaaaa atggtagatt tgcatgttga gaaatgtaaa aagtagatat
    55861 acatctgaag tacaggcgta taaacattaa agttgtaatg atataaaggt ttaaaaaagg
    55921 agttgagctt caaatttaat taaaaaaatc aattttaaga caaccccctt aagtaatgca
    55981 attattcata tttgaagtgt agttaatttt taatttttta taatattact agcatattaa
    56041 gatattctaa ctattttcgc ataattctcc taaaatctta tgaatatgaa tcatcaaata
    56101 taactcctct tgtcttggta attctctgga gtattcctta tacatataag ctcctacctt
    56161 tttcacacat tcatactctt ccttacaatt tttttgaact tgctcatata taaaatctat
    56221 tttttctctt gatggttcat tagccagaaa tctttgtgaa aaggccttta gatgcattac
    56281 aaatctccta taataaaatg actctttatt atatacaata gaaaagtgat aatgaactat
    56341 ttgcaaaata gcatttacaa ttttagcact tctcttattt ctatcactat aaggattatc
    56401 ttgttgtgca tttataaaat ggcctgctat attaccaatc tcttcttctg gtaggtctaa
    56461 accaagaacc tccttaaaaa cagtaatagc atattttcct atatcatact cttttggatt
    56521 aaattccttg atttcgaaca aatagtgatt ttcaatcatt ataccttctt taaaacgtct
    56581 cactgcaaag gcaatgtggt cagttaaggc caaatatata tggttcataa gttttaagtt
    56641 atatttttct attccatatg caattatcat ttgagctata ccaaaatatt ctgcatctat
    56701 ttctgttgcc aattgtataa tactcttttt tatattttca tcatgaagaa caaaaatctt
    56761 ttctatatct tttttattta actcagaccc ggccttataa ttatggccaa tgcctttccc
    56821 catcaatatt atttcttcat cattatcatc ctttgcaagt agcaacgaat tatttaatac
    56881 ctttgtaatg tacatactaa aaccctcaat atatatttat gtttatttta ctattccatt
    56941 gttctctata acttctttat accagtaaaa actatctttc ttgattcttt ttaaatctaa
    57001 aatttcatgg tcagttctat ttatataaac aagtccataa cgcttattaa aaccttgaga
    57061 agaacttaaa aggtctgtaa atgaccatgg acaatatcca atcatctcta caccatcttc
    57121 aatagctagt ttacatgcat ttatatgact tcttaaatag tctatacgat agtcatcatg
    57181 aatttttcca
//
LOCUS       DAGQVA010000017        56224 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.017, whole genome shotgun sequence.
ACCESSION   DAGQVA010000017 DAGQVA010000000
VERSION     DAGQVA010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.017"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            162..551
                     /locus_tag="MIV85_001202"
     CDS             162..551
                     /locus_tag="MIV85_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2960568.1"
                     /translation="MKQQEVVNKLRRGELMLMEYLWRKNSILSKKEIIEAMKEKYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFQFSYEVLVTKKEYLNAIKEDRKVTKYDSFFIRMF
                     TTMHKKEKMTEEQIKKYIENMEKIGKE"
     gene            645..1028
                     /locus_tag="MIV85_001203"
     CDS             645..1028
                     /locus_tag="MIV85_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2960569.1"
                     /translation="MGFKKLPDSELKVMKFIWGLDGNKVASGEVVEAMKQIYDWNKNT
                     TLTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTAL
                     NDEENLSDDKLDMLEEWVKNWEEDE"
     gene            1707..3137
                     /locus_tag="MIV85_001204"
     CDS             1707..3137
                     /locus_tag="MIV85_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBY2960570.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(3285..3635)
                     /locus_tag="MIV85_001205"
                     /pseudo
     CDS             complement(3285..3635)
                     /locus_tag="MIV85_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            3630..4151
                     /locus_tag="MIV85_001206"
     CDS             3630..4151
                     /locus_tag="MIV85_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBY2960571.1"
                     /translation="MFSIGGGYAIILLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(4280..5074)
                     /locus_tag="MIV85_001207"
     CDS             complement(4280..5074)
                     /locus_tag="MIV85_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2960572.1"
                     /translation="MIFCNSFITRKSSMNIVVTHTPIVTTLEMQKAYEPLAKHNVNIF
                     AFDFSGTGKSDGYEKDFSRNSIVKDLDSVITYIEKNYSSNIHLYGNTGIGGMFAQYYA
                     CSDNKLKSFAQFACVDYKNTTGVGYTYLTVKLLNFFFKFLPNFHITVKPPKYKGYNEV
                     YDNEFYKIFEKKNPHIWKNSTKIINTMLECFIAKDSKIKDGVNIPTLVFKTLHDRYFK
                     TQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(5298..8726)
                     /gene="uvrA"
                     /locus_tag="MIV85_001208"
     CDS             complement(5298..8726)
                     /gene="uvrA"
                     /locus_tag="MIV85_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBY2960573.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHQDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLKGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            9045..11279
                     /locus_tag="MIV85_001209"
     CDS             9045..11279
                     /locus_tag="MIV85_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2960574.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            11535..13565
                     /locus_tag="MIV85_001210"
     CDS             11535..13565
                     /locus_tag="MIV85_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2960575.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            13562..14014
                     /locus_tag="MIV85_001211"
     CDS             13562..14014
                     /locus_tag="MIV85_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2960576.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            14016..15071
                     /locus_tag="MIV85_001212"
     CDS             14016..15071
                     /locus_tag="MIV85_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBY2960577.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            15138..15446
                     /locus_tag="MIV85_001213"
     CDS             15138..15446
                     /locus_tag="MIV85_001213"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBY2960578.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            15550..16815
                     /locus_tag="MIV85_001214"
     CDS             15550..16815
                     /locus_tag="MIV85_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBY2960579.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            16903..17619
                     /locus_tag="MIV85_001215"
     CDS             16903..17619
                     /locus_tag="MIV85_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBY2960580.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(17814..18107)
                     /locus_tag="MIV85_001216"
     CDS             complement(17814..18107)
                     /locus_tag="MIV85_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBY2960581.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(18113..18328)
                     /locus_tag="MIV85_001217"
     CDS             complement(18113..18328)
                     /locus_tag="MIV85_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960582.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAMQQFIVENEILISEEV"
     gene            18777..19175
                     /gene="tnpA"
                     /locus_tag="MIV85_001218"
     CDS             18777..19175
                     /gene="tnpA"
                     /locus_tag="MIV85_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBY2960583.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            19172..20335
                     /locus_tag="MIV85_001219"
     CDS             19172..20335
                     /locus_tag="MIV85_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBY2960584.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(20719..21231)
                     /locus_tag="MIV85_001220"
     CDS             complement(20719..21231)
                     /locus_tag="MIV85_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2960585.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            21681..22157
                     /gene="purE"
                     /locus_tag="MIV85_001221"
     CDS             21681..22157
                     /gene="purE"
                     /locus_tag="MIV85_001221"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBY2960586.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            22163..22861
                     /locus_tag="MIV85_001222"
     CDS             22163..22861
                     /locus_tag="MIV85_001222"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBY2960587.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            22873..24240
                     /gene="purF"
                     /locus_tag="MIV85_001223"
     CDS             22873..24240
                     /gene="purF"
                     /locus_tag="MIV85_001223"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBY2960588.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            24234..25310
                     /locus_tag="MIV85_001224"
     CDS             24234..25310
                     /locus_tag="MIV85_001224"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBY2960589.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            25304..25897
                     /locus_tag="MIV85_001225"
     CDS             25304..25897
                     /locus_tag="MIV85_001225"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBY2960590.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            25890..27422
                     /gene="purH"
                     /locus_tag="MIV85_001226"
     CDS             25890..27422
                     /gene="purH"
                     /locus_tag="MIV85_001226"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBY2960591.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAVVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            27433..28683
                     /gene="purD"
                     /locus_tag="MIV85_001227"
     CDS             27433..28683
                     /gene="purD"
                     /locus_tag="MIV85_001227"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBY2960592.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTRVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            28708..32514
                     /locus_tag="MIV85_001228"
     CDS             28708..32514
                     /locus_tag="MIV85_001228"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBY2960593.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDNKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVIGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            32720..33592
                     /gene="rfbD"
                     /locus_tag="MIV85_001229"
     CDS             32720..33592
                     /gene="rfbD"
                     /locus_tag="MIV85_001229"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBY2960594.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            33701..34570
                     /gene="rfbA"
                     /locus_tag="MIV85_001230"
     CDS             33701..34570
                     /gene="rfbA"
                     /locus_tag="MIV85_001230"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBY2960595.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            34619..35176
                     /gene="rfbC"
                     /locus_tag="MIV85_001231"
     CDS             34619..35176
                     /gene="rfbC"
                     /locus_tag="MIV85_001231"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBY2960596.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            35214..36197
                     /gene="rfbB"
                     /locus_tag="MIV85_001232"
     CDS             35214..36197
                     /gene="rfbB"
                     /locus_tag="MIV85_001232"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBY2960597.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            36227..36895
                     /locus_tag="MIV85_001233"
     CDS             36227..36895
                     /locus_tag="MIV85_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBY2960598.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            36904..37332
                     /locus_tag="MIV85_001234"
     CDS             36904..37332
                     /locus_tag="MIV85_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBY2960599.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            37356..37670
                     /locus_tag="MIV85_001235"
     CDS             37356..37670
                     /locus_tag="MIV85_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBY2960600.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            37822..38097
                     /gene="flgM"
                     /locus_tag="MIV85_001236"
     CDS             37822..38097
                     /gene="flgM"
                     /locus_tag="MIV85_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBY2960601.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            38102..38518
                     /locus_tag="MIV85_001237"
     CDS             38102..38518
                     /locus_tag="MIV85_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBY2960602.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            38536..39846
                     /gene="flgK"
                     /locus_tag="MIV85_001238"
     CDS             38536..39846
                     /gene="flgK"
                     /locus_tag="MIV85_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBY2960603.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            39865..40797
                     /gene="flgL"
                     /locus_tag="MIV85_001239"
     CDS             39865..40797
                     /gene="flgL"
                     /locus_tag="MIV85_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBY2960604.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            40813..41205
                     /locus_tag="MIV85_001240"
     CDS             40813..41205
                     /locus_tag="MIV85_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBY2960605.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            41199..41411
                     /gene="csrA"
                     /locus_tag="MIV85_001241"
     CDS             41199..41411
                     /gene="csrA"
                     /locus_tag="MIV85_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBY2960606.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            41433..41828
                     /gene="fliS"
                     /locus_tag="MIV85_001242"
     CDS             41433..41828
                     /gene="fliS"
                     /locus_tag="MIV85_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBY2960607.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            41828..42184
                     /gene="fliS"
                     /locus_tag="MIV85_001243"
     CDS             41828..42184
                     /gene="fliS"
                     /locus_tag="MIV85_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBY2960608.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            42205..43728
                     /gene="fliD"
                     /locus_tag="MIV85_001244"
     CDS             42205..43728
                     /gene="fliD"
                     /locus_tag="MIV85_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBY2960609.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            43731..44066
                     /gene="fliT"
                     /locus_tag="MIV85_001245"
     CDS             43731..44066
                     /gene="fliT"
                     /locus_tag="MIV85_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBY2960610.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            44168..45040
                     /locus_tag="MIV85_001246"
     CDS             44168..45040
                     /locus_tag="MIV85_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBY2960611.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            45133..47274
                     /locus_tag="MIV85_001247"
     CDS             45133..47274
                     /locus_tag="MIV85_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBY2960612.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            47298..49175
                     /locus_tag="MIV85_001248"
     CDS             47298..49175
                     /locus_tag="MIV85_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBY2960613.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            49168..51282
                     /locus_tag="MIV85_001249"
     CDS             49168..51282
                     /locus_tag="MIV85_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBY2960614.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            51291..52286
                     /locus_tag="MIV85_001250"
     CDS             51291..52286
                     /locus_tag="MIV85_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBY2960615.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            52378..53610
                     /locus_tag="MIV85_001251"
     CDS             52378..53610
                     /locus_tag="MIV85_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBY2960616.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            53630..54574
                     /locus_tag="MIV85_001252"
     CDS             53630..54574
                     /locus_tag="MIV85_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBY2960617.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            54668..55075
                     /locus_tag="MIV85_001253"
     CDS             54668..55075
                     /locus_tag="MIV85_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBY2960618.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            55162..>56224
                     /locus_tag="MIV85_001254"
     CDS             55162..>56224
                     /locus_tag="MIV85_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBY2960619.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVS"
BASE COUNT        22315 a         5947 c         9894 g        18068 t
ORIGIN      
        1 aattgtttga aaatttaata attttataga tatgaaagtt attttcttct aagaaaacag
       61 actaaatgcg tagaatattt ggtaaaactt acctgtataa attgaaatca gaaggtttta
      121 ttattgattt agattagaac aatttgaggg agtgacataa aatgaaacaa caagaagtag
      181 ttaataaact acgcagggga gaattgatgt tgatggaata cttgtggagg aaaaattcta
      241 ttttatctaa aaaagaaata atagaagcaa tgaaagaaaa atataagtgg aggaaaagta
      301 ctacagaaat tctattaaaa agattagtaa aaatgaaaac attaaaaaag aagaggatag
      361 gttttcagtt tagttatgaa gtgctagtaa ctaaaaaaga atatttaaat gcaataaaag
      421 aagatagaaa ggtaactaaa tatgatagtt tttttatacg aatgtttacc actatgcata
      481 aaaaagaaaa gatgacagaa gaacaaataa aaaaatatat agaaaatatg gaaaaaattg
      541 gaaaagaata atttatatat atattaatta tttttaaaat aaatttgtta taatatttaa
      601 atatacataa acatacataa atttacaaaa agggggtgta gcttatggga ttcaagaaat
      661 tgccagattc tgagttaaaa gtaatgaagt ttatttgggg attagatgga aataaggtag
      721 catcaggaga agttgtggaa gcaatgaaac aaatttatga ctggaataaa aatacgacat
      781 taacaatatt gtctaagctt gcaaagaaaa actatttgta ttctcaaaaa acaagcaagt
      841 gtacatatta tactatcgct gtaagagaaa aagattattt aaaagttgaa acaaaaaaat
      901 tctttagttt ttttcataat aattctttaa aaagtttttt cactgcttta aatgatgaag
      961 aaaatttaag tgatgataaa ttagatatgt tagaggaatg ggtgaaaaat tgggaagaag
     1021 atgaataaaa tgaatgtgat actaaaatga tactaatatg ttttatagcg tgttaaaaaa
     1081 tatagaaaat atagaaataa tagaagaaaa ttaatgtaat agataaggtt ttatcagatt
     1141 aaaaagaaaa tcaatagaat gggaataaaa tatagaatgc caaaaatcca cataaataca
     1201 ggatttgagg tctctcttac ttctatgtta tactggtttg atactatcaa tatttgccag
     1261 tatcttatgg attaataagc aaaaaacatc ctgctgaatg ataaattcag cggggtgttt
     1321 ttattttgtt ttagaactcc tttgctctga aactcgaagt atttaacact gatgattttg
     1381 ttatctttta gttccttttg tgtcatgctc tgaaagacaa attgatacaa taaaaaagta
     1441 atttcttaat cattgatgga gatatgtgtt tatgttactc ttgatggtaa tttgagtaat
     1501 attgttcata gctttttata ttcacttaat tagaaaacca tttggtataa tcataaataa
     1561 acttgatgat ataatagaaa agatttataa ttattagaag tatataaaag tattttatgt
     1621 ctatgaaatg tatgtctata aaacatatag atgacttttg tatattaatg tatgaatatt
     1681 gatattatag aagaattgag ttgtcaatga tactaaatca aatatttata gaagctggag
     1741 ggattatgag aaataaaata attataggaa ttactttttc acttgtatta ctaatgtctg
     1801 gatgtgcttc aaaacaaacc gcagaaataa acgtattagc aactactgat ttacatggag
     1861 ttatacctta tgagttaact tcttatgtaa aagaagaaag aaaaaaagat aaaaatctaa
     1921 ctttagtaga tgcaggagat ttttttgata gtggagaagt gtttggttct agcatggata
     1981 gttattttag tgctagatat aaagatggtg ataataacac tgaaagttat attgagacgc
     2041 ctatttcaaa agatatgaaa gaggtaggtt atgatgttgc agttcttggg aatcatgaat
     2101 ttatatccaa caataaattt tatctagata atatgatatc tgattttgag aagcaaaaaa
     2161 taaatatttt atcggcaaat acgtataaaa aaaatggaga tagttataca aaaccataca
     2221 taataaaaaa tattaataca cctgaaggaa acgtaaaact aggaatttta gggcttacta
     2281 taaaagaagt tggtgagagg aaacagtgga aagatggaaa acttgttgac tctaagtctt
     2341 tagaactaaa agaccaagag ggttacaatg gtgaattgta tatgaatgat ttagtagaag
     2401 atgctaaaaa gtgggttggt ataatggaaa aagagaagcc tgacattata gttgctgtgg
     2461 cacatacagg tgagaaacct aagaaaccta aaaacccagg aaatagaata caagacttag
     2521 ctcaacaagt tgatggaatt gatgctatag ttgcaggtca taatcatgtt caaattgagc
     2581 aacatgatta taaaaataaa tcaggagaaa atgttatagt tactgagcca ggaaagcatg
     2641 gggaatgtat ttctaagatt aattttaaat tagaaaaaaa caatgataaa tggaatatag
     2701 ttgacaaatc tagtaaatta attaaatttg aaaaaaatca agaaagtgat aaatttggag
     2761 aatttatttc ttcaattaat aaagtaagta aagataagaa agaaataaga ttatcagaag
     2821 taaagactcc tgaatgggat aaaatatatg tttttaaatc tggaacatct gcagatgata
     2881 tatataaaac aataggatat aaatggagaa atatatcatc tccaaagggt gatgacatgg
     2941 tgcagattgt tgtaatgaat aataataagc ctgttagcta tgtatatggt gaagctgaag
     3001 ttatgccaat taatataaaa tgtgatgaat cagagtataa agataatgtt gtaactattt
     3061 atcctaataa aaatgataaa tttaaaattg aaaaaggtaa acaagaatat agtattaatt
     3121 taaaacatat acaatagaaa cttttatctt atttaagttt agattgtact taaaataaag
     3181 tgtgtattat tttaaaaatt gatgataatt aaaatcacaa cattaaagaa tagtacacac
     3241 tttttatgct aaaaaataga atgttaaaaa attaaacctt taaattaaag tacattgctt
     3301 atattatcca atattatttt caaaggttgt gtaatatttt tatccttatg taatattgct
     3361 aacattttat tttccatatc tatcccatct aattcaatca atcgcaattt tttatgtaag
     3421 agtgaatcta ataataaatt ttctggcaaa atggttatac ctaaccctgc ttgtgcagct
     3481 ttaataagtg caaaagaatt aacactttcc caaacaggat aagctttttg gtttgaaaga
     3541 gataatacac tgtccaaagt attgcgaatg gcacttcctt gctcacgtaa caataacgga
     3601 aacgtgcata actgtcgtag agataaggct tgtttagtat tggtggtggt tatgcaatca
     3661 tacttttaat ccaagagaaa gtagtaaatc aaactggatg gataagtgag aaaatgttta
     3721 cagatattat aactatttca caaatgacac cagggccact ggctgttaat acttctactt
     3781 ttgttggact tcaaattgga gggttttggg gagcagttgc agccacttta ggttgtgtat
     3841 tatgtggtgt agtaatatct ctatttttat ataatttttt tcaaaagcat cagaactcta
     3901 cttatatatt tgaaatatta aatggtctaa aatcagcttc attaggttta attatctcag
     3961 ctgcggctac aattataatc cttgcattat ttgggacgaa taaagtgtac ttcaattcta
     4021 tatttgagat gctaaactgg actgcactaa taatcttttt tgttacacta ctgatagtac
     4081 gtaagtggaa aattaatcct attgtgatta taataataag tggtatactg ggaatatttt
     4141 tttatttata agtttttggt aagtagagga tatctatttt tttatatctt aaatccaaat
     4201 agccaataaa gtaaggccat ttggattttt aataaattct gaaaagataa tcagaaaccc
     4261 atataacatt taaattatat cactggtttt ctacaaacca atcataagct tcttggcaaa
     4321 atttctcact atctatatag taactattat gaacattatt aatttcaaca agtttctttt
     4381 tacattttag tgaattataa tagctatcaa aatattgggt tttaaaatat ctatcatgaa
     4441 gtgttttaaa gacaagagta ggtatgttga ctccatcttt tatcttacta tcttttgcaa
     4501 taaagcattc taacattgta ttaattatct ttgtactatt tttccaaata tgaggatttt
     4561 tcttttcaaa tattttataa aattcattat catagacttc attataacct ttatatttag
     4621 gtggttttac tgttatgtga aaattaggaa gaaacttaaa gaaaaagttt aataatttaa
     4681 cagtgagata ggtatagcct actcctgttg tgtttttata atcaacacaa gcaaactgag
     4741 caaaactttt taacttattg tctgaacatg cataatattg tgcaaacata ccaccaattc
     4801 ccgtattccc atatagatgt atgttggaag aataattttt ttctatgtat gtaatgacag
     4861 aatctaagtc ttttacaatt gaattgcgag aaaaatcttt ttcatatcca tcacttttcc
     4921 ctgttcctga aaaatcaaaa gcaaatatat ttacattatg tttggcaagt ggttcatatg
     4981 ctttttgcat ctcaagcgta gtgacaatag gagtatgtgt aacaacaata ttcatggatg
     5041 attttctggt aataaatgag ttacaaaaaa tcattgtatc tccatttggt atttttatat
     5101 gtttccaact catttgattt tcctttctct attataaaat ataataattt ttatgttctg
     5161 ttttatatat tattcatatt ttatcacaga taatatacta aagttaattt ttttattgta
     5221 cacctattat aataattctt ctataatata agacattcta taattttata tttaagttca
     5281 tgtgtattta attgttttta tataaaatgt ccagtaatac tatttggatt tatttttatt
     5341 tcatcaggag ttccagaagc aacaatttcc cctccattta ttccactgtc tggacctata
     5401 tcgataatcc aatcagaagc acgtataacc tctgtattgt gttcaataat taaaagtgaa
     5461 tgctgttcat ttacaagttt tctaaaagta attaacaaat tttctatatc tttaaaatga
     5521 agtccagtag taggctcatc caatatgtac agcattcgtt ttttagtttt tgtccctaat
     5581 tcttttgcta attttatcct ttgagattct cctccactta atcctaatgt attttgtcca
     5641 agctttagat atccaagtcc cacttcatct aataaggaga gttttctata tatatcagag
     5701 caatcgctaa aaaatgtttt tgcttctgct acttccatgt caagtatatc tgcaattgtc
     5761 tttcccttgt attgtataga cagtatttct ttttgatatc tcttaccttg acattcacta
     5821 caagttaccc attggtctgc catatattgc agaataattt ttgttttacc taatccttga
     5881 cagtttgggc attgcccctt tttgctatta aagctaaaat agctttcatc caataatttt
     5941 tgttttgctt gtggagtttc agcaaataga gaacgaattt catcaaaaat attgatatat
     6001 gtagcaggtg tagaacggct agattttcca ataggtgttt ggtccattaa gataaaatca
     6061 tcaatagcat caaatccagt aaattcagta taatttttat ctgggataga tttttgtttc
     6121 aatttttctt ctagagcagg aagtaaactg tgaaatacaa gagagctctt accagaacca
     6181 ctaacacctg taatagagca catacagttt aagggaattt ctacatcaat attttttaag
     6241 ttatttgcat ggcatccttt taagcttaac catttacttg gtataatttt attttgtgaa
     6301 cttattttat tgtatgtgct taaatattta cctgttatag agtttggatt ttttataatt
     6361 tcttgggttg taccttctgc aataatgaac cccccttttg taccagcact tgggcctaca
     6421 tcaataatat aatcagcaga cagtattgta tctttatcgt gttccacaac tataacagta
     6481 ttacccttat ctcttagctc ttctatcatt ttgatgatta aattatggtc tcttgggtgt
     6541 aaaccaatag atggttcatc taaaatgtag gttaagccta ctaattcact tcctagctga
     6601 cttgataatc gtactctctg cagttctcct ccagataaag ttggagctgt tctatctgtt
     6661 gatatatagc taagacctac ctttaataga taactaactc gaatttttaa ttctgttaag
     6721 atatcattta ccaaagagag ctcatttttt tgaagttgat ttggtaattc acacaaccaa
     6781 ttccataact gttctatcgt catttttgtt agttcaggga agcgataacc tttgattgta
     6841 gtgaatctag cctcaatgca cagcaattcg ccaccacatg tattgcaagg aattttgttc
     6901 atatattgat gcaaggtatt attttcagaa ctagattctc taaaaagtct ttgaatgtgg
     6961 ttgattgctc ctgaagcagg tcttctaatc tttgattctc gtccctttga ttcaaagcta
     7021 aattcatata tcttatcgtc tgtaccatat aagattgcat ctataaaatc tcttggtaat
     7081 tcattccaag gtatatctag gtctatattt ttatcttttg ctattgcata taattcacct
     7141 accatccaat taccatttgg ctttttcccc ttcaattttc caaaatagta agtagctcca
     7201 tctaatattg aaatagttgg gtcttttaca atcaattgag gattaacttg ataggtaaaa
     7261 cctaatccat tacaatcgtg acaagctcca gtatgggagt tagcattgaa ggttgaagta
     7321 tttatcttag aaaaaatagt ttgacaatgt ggacaataat tttttgtatt attctttttt
     7381 tctaatggaa ttttacaata tggacagtaa ctttttccga ttgatacaaa taacattctt
     7441 aaataatccc aaatgcttgt aagagtacca acagtagagc gaggattttg gcttcctttt
     7501 ttctgttcga tagctatagt aggggttaat ccctgaagta aatcaaattc cggtttttga
     7561 agctgttctg aaagttttgc tccattactt agattttcaa aataacgtct ttttccttct
     7621 tcataaatcg tatcgaaagc taaagaagat tttccactac cacttacacc tgtaataaca
     7681 gttatttgat tttttggaat tgtaacctca acatccttta aattgttttg ccttcctcct
     7741 tttaaataga tagagctttt attatgacaa agtgaatttt taattgattt atttattgat
     7801 tttgtaaatt tgaatttctt ttcgagttca agaggattgc ctaattcttt tatttccgaa
     7861 atgcctaata tttttaactg agaaaagatt gatttcaaat aatcttcagg caatttttct
     7921 attaacaaat taaggtcttc tatttttata tttccgcttg ataatatttc tgccatttca
     7981 tctaataaat ttttttctgc tcttgttaat tgattgtatt ttttggaact taattctgtc
     8041 cataaatccc atggaagcaa ttctaaacca atcatattat taaagtcatg tagaagatta
     8101 ccctttacag aatgccaacc tttccaattt ttattatatc caaagtcatc ttgatgagca
     8161 tgtccttgcc gacatcttat ccaggcttct gaaccagtta aaaaaccatc tgtttttccg
     8221 acatcatgag tgtcaaaatt aatttgaaaa taattttttt gtatgtcatc tatttgtgca
     8281 tctattctta tccatctctt tgttagagta tcatagtatt ctacaagcca gtggtcttca
     8341 taagtaagct cactttcaaa ataattagca aaacctgctc tcattctagc ctcaaaacct
     8401 cgatatctta ggagcgatac aagaagtaaa gaataatctc tgcacattcc aacaagcctt
     8461 tgttttgggt ttcttggaat agttagtggg ttagaattta tttcaaatat tctttttaac
     8521 atttgaggaa ttgtacgaag caattcctca tcagattgtt gtttattaaa ggatatacca
     8581 tataattttc cttggtctcc atgaattact aggctttgaa ccacttttaa taactcaatt
     8641 ggagtctttg gtaaatcttg atatttattt tcaaattttt taggatttgt gatgatgctt
     8701 tgatttttat agttatttat tttcatttat atttcacctc tctaaatgga tgatataccc
     8761 tgacatggtg tcatatgcaa gggcaattta aattttttgg ccaaaattta aaaataaata
     8821 aaaaatgata cagtgataaa ttgtaataca aatatagttt caaattgcat ataatataat
     8881 tatttaataa aaccattatc tatggaatgt taatgaaatg ttaagatggc attcttgaat
     8941 attaagaaat agaatactat aatatagtgt gaaggatttt tagtaaaaaa atttgtaagt
     9001 gttaatatac attaaaaaat agatttataa tttggaggaa aaaaatgaaa ttatcaaggt
     9061 ataagaaaaa tagtttagtt ctgtctataa ttttatgttc acttattatt tcaatccttg
     9121 taattactgt ttttaatacc gtaaaactac acaatatatc taataaacaa tctaaaaact
     9181 atttaaatga tgtatctaca cagattgtaa tgaatgttga ttctaaaatc aaatttattt
     9241 tatccgactt aagaataatg gcagatttta ttaagcaata tgaaggtgat agtcgatatg
     9301 agtatttatc taaaagaaag actagttata agtattatga tgttggaata atagatttag
     9361 aaggtaaagc tgagttttta agtggaaaaa agtttgactt aaagaatact gtttcctata
     9421 aaaaaggaat tgaaggtaaa gaatactcag aagtaataga gtcaatgggt tttgttcttt
     9481 atagtgtacc tatatttaat gataatcatg aagtatctag tattttaata ggtgtatcca
     9541 ataaagaaag tatgaatgag attcttaata tagataactt taatggaaaa ggaactattg
     9601 aaattattaa tagtaaggga aaacctcttt tcataggaaa aaatactgaa ttaataaagg
     9661 accttagcca taaatataag agttctggag atgaaccttg ggcacaaaag atgcttgagg
     9721 attttaaaaa tgataaatca gggaatatta caataacctc atcaaaaggt gtacaatgct
     9781 tattaactta tcatccaatt acaagaggtt taaatgattg gcattttctt ctcatagtac
     9841 ctgaagatgc tgtacttggt gaacttaata aattaaactc ttttacaata acaatgacat
     9901 ttataattac atgtattatt ggaattataa cattaatttt atatattata agaagaaaat
     9961 atgtaaatca aatagaaaat attgcatatt tagatagtat aacaaatggt ataaattcaa
    10021 ctaagtttag tatgctagtc aaacctttaa tttcagaatc acctgatagt acttatatga
    10081 tgatagcaat gaatataaaa gattttaagc taataaatga ttgtttcggt agtgaaaagg
    10141 gaaatatgac actaaaacat ctttacaata ttttgtataa aaacattgat gaaaatgaag
    10201 agtttgtgtg ccgtcatgat gcagaccttt tctatttgct tattaagaat agaccagtgt
    10261 tagaagccct ggagttatta tataaaatag aagctgacac aaattatttt aataaaaata
    10321 gggaaaatcc atacttttta agactatcag taggtattta cacaattgaa aatcataatg
    10381 aagatttaat tacaatacaa gaccatgcaa atacagcaag aaaaagcttt aataaaactc
    10441 atcaaagtga tttttctttt tatagtgata tagaaagaaa acgattaata tctgaaaagg
    10501 aaatttcaaa tttaatggaa aaagcccttg aaaataaaga attttttatg tgcttacaac
    10561 ctaaaattga tataaaaagt ggaaaaatta gtggagcaga gtctcttgtg cgttggaaaa
    10621 attcagaaaa gggcataatt tatccaagtg attttattcc tcttttcgaa aaaagtggat
    10681 ttatatgtaa gttagattta tatatactag aagaaacatg caaattgatt tctaagtgga
    10741 taaaagaagg taaagaagtg ttgagaattt ctgttaatgt atcacgtcaa catctgaatg
    10801 ataaattgtt tttagaaaaa tataagcata tatgcaataa atacaatgta ccaacatgtc
    10861 tgatagattt agaacttact gaatctattt tcttagaaaa tccagaagct atagatataa
    10921 tagaggatat tcattctaat ggatttaaat gttctataga cgattttgga tttgggtact
    10981 catcattagg gatattaaag gattttaaag ttgatataat taagttagac cgttcattct
    11041 ttgttagcaa aaataatata gaccgtggta aggtagttat taagtctatt attgaactta
    11101 gcaaaaggct aggtatgaaa gtaactgctg aaggaattga agaattagaa caagttgagt
    11161 tcctaaaaaa tgtgggatgt gattatattc aaggttatgt tttttcaaaa ccattattaa
    11221 tttctgactt tgaaaatttt gcatatgaaa ataataaaat taaaaatatc cattattaaa
    11281 tgtacaagat aaaaaattta ggcaagttat ataattaaaa atataacttg ccttttttat
    11341 ttatatattt aataaaaata tatttgcaga ttttgtaaaa ataattttca aatgttgtaa
    11401 gttgtggcta aagctttatt gtattattct gaatatagaa agatagttac tgtcttagat
    11461 aaaaactgaa acatacataa taatataaaa tttgctatat taataactct aattattttg
    11521 gaaggaggga aaatatgata agtgggagaa tgttactcat catgaatttt ctaaaaggaa
    11581 aaaataagac aagttacaag gatattagca aacaacttag tatagaagaa agaaaagtta
    11641 gatatgatat aaataattta aatattgttt tgcgttcatt aaacaagtca gtaatacaaa
    11701 agatgaacaa aggtgtgtta attattcctg atgacttcca agtagtatgt ataaataata
    11761 acgaatatgt attttcctta actgagcgag tatctattat gaaaattata tcaatgttta
    11821 aaatagataa tctaaactta gaaaaattaa gtaaagaatt tcaggtttct agaagttcaa
    11881 ttaaaaatga ccttaatgtt ttgtcaagtg aattagaaag aaaccaaata actattactt
    11941 atgataaatc ttttaaaata agtggagaag aagacattat atataagcaa agattgaaca
    12001 tattaaaatc gtattcttat ctttttggta aggaaaaatc tgatttaagt gtatttgaga
    12061 agtatttagt gaatgtaatt gaaaaaatat tcaaagggat ttatttgatt gatatatata
    12121 attggtctat gaatttatta ttgcaaatgg gatggacttt aaatgatgaa tcttttacat
    12181 ggtatgtgtc aaacattttc ctttttacat ggtatataca ttcagatgaa aaacatcctt
    12241 tagaatctgc ttcattaagt gagccgtgtt ttgaaaataa gtttgaccaa gaatttgaaa
    12301 caattattca aaaaaagttg actaaggaac aaatttttct gttaaagagt tttgtatttt
    12361 ttacaaataa atatgcaagt ttaaacgagg atatggattt gattagtaca gaaattatag
    12421 ttcaagacct aatttacaat atgtcagaaa tattagagat tagctttaaa gaagatatga
    12481 ttctttataa aggattactc aatcatattg ccccattgat agagagaatc aagcagaata
    12541 tacagattta tgaggaatta cttcatgtaa taccagataa atatcaatat gtacttgaag
    12601 ctactaaggt ttctattcaa aaaaacagag ttttaagtca aataaagaat gaaaatgaaa
    12661 caatactttt ggcaatacat ttcttaggaa gtatacatag aaatgagagg aataactaca
    12721 aaaatatatt gttagtttgt ggatttggat atggtgtaat tgctatgtta aaggatagtt
    12781 tagtaaatga ttaccagata aatatagtag agagtattcc atcatataag ttacaagatt
    12841 ataaagactg ggaaagtatt gacttcatta taacaacatc aaagatagta atagacttgc
    12901 ctaaaacaat tattgagata aatccatttt tacaagaaga ggattatttg aagtttgaag
    12961 aaaaagggat aaaaagaaag aatgtcttaa ctaattatat gtcaataaaa aaaaggttgg
    13021 actttttaga agaagatgcc caaaaaagag tattaagtat tatatgtcaa gaacttggat
    13081 acagtgatga gagaatatta tttagacaac ttaatttaag tgatttaata gggattgata
    13141 ccataaggat aattgatgga gatatgaaat gggaagatgc tgtaaaattt agttcaaaca
    13201 tacttgctaa ttgtgatttt gtatcagcac aatatgctga gaatattata gatattttaa
    13261 aaaatgtggg tttttatgct gtaaaagata acgaatttgc tttactacat ggcaatgata
    13321 gttcattagt caaagtaagt tcgataagtt tattaatatg taaagaagca gttagttttg
    13381 gagataaaaa ggttaaaatc atattttgcc tagcaagcag agataaaaaa gagcaaattc
    13441 ctgcaataat taatctaact aaaatggttt ataagactaa ttttattgct atgttagaaa
    13501 gtgcaaagac aaaagaagaa gcagaagttt taattcataa atatgagaag gaggtcactg
    13561 tatgaataaa ttagttaatg taaaatgttc atttaaaata catgttaatt caaaagaaga
    13621 agccattata tcgttagttg atgtagtgtc aaaagaagga tatttaatag ataaaaatca
    13681 atttttaaaa gatgttttaa agagagaaga aacattgtcg acttatattg gacatggtat
    13741 aggtcttcct catagtcaaa gtgtaggtgt taaaaactct tgtattacaa taggaaagct
    13801 tgatactcct attgaatgga cagaagaagg agaaaaagtg gatttaatat ttttgatatc
    13861 agtaacaaaa gacaatgaaa ataatcttca tttaaagatt ttatcaaaat tagcacgttt
    13921 attgatgcat gaaagtttta gaaatcaaat tagatgttca gatgaacaaa ctgtttataa
    13981 tcttataaaa gaaaaaatag aggaggaaga ttaaaatgag aattttaaag tttttgcaaa
    14041 aacatcttat gacagcaaca tcttatatga ttccatttgt ggttgcagga ggaatattat
    14101 ttgctttatc agtaacttta agtggacaag ctgctgttcc tgaaacaggc tggttggcta
    14161 aactgaatca aattggagct gctggcttgg ctttattcat tcctatatta ggtggatata
    14221 tagcatttag tatggcagat aaaccaggat tagctccagg tatgataggt gcatatttag
    14281 caaaagaagt aaatgcaggt tttataggtg gtatcatagc aggatttata gcaggatttg
    14341 ttgttttaca attaaagaaa attaaattag ctcctacaat gagaacttta ggttctatat
    14401 ttatttatcc tttagttggt acattgatta caggtggtat aattgtattt ttaattggag
    14461 aacctatagc ttcttttatg acatggatga caaactggtt aaatggaatg tctggtgttt
    14521 ctaaaattcc tttaggtgga atcttaggag gaatgatagc ctcagatatg ggtggcccta
    14581 taaataaggt tgctgctact tttgcccaaa ctcaagttga cacacttcca tatttaatgg
    14641 gtggagttgg cgttgcaatt tgtatacctc caattggttt aggattagct acattattgt
    14701 ttccaaaaaa atttagcaag gaagaaagag attcaggtaa agcttcacta ttaatgggat
    14761 gtgttggaat tacagaagga gctattccat ttgcaacatc agatccagtt agagtaatac
    14821 cttgtattat ggctgggtcg attgtaggaa atattatggc ttttttatta ggatgtttaa
    14881 atcatgcacc ctggggaggt ctgatagtgt tacctgtagt tgacaatagg ttggggtata
    14941 ttgcatcagt attaactgga gcagtagttg ttgcggtatt aatgaaatta gtaaaaaaag
    15001 acgtgaaaga agatgaagaa attgaagaag atttagatga atcaattgaa ttaatatttg
    15061 aagaattata aatataaatg gaaggaattt gtataaaaaa gtaaatataa aactataaat
    15121 ttaaaggaga taagaatatg aaaattgtag cagtaacatc ttgtcctagt ggagtagcac
    15181 atacttacat gtcggctgaa tcacttgaat tatcagccaa aaaatttggt atagaaataa
    15241 aggttgagac tcaaggaagc tctggaatag ataatgaatt gtcacttaaa gatattgatg
    15301 aagcaacttg tgtaatattg actaatgatg ttgagattag aaatatggaa cgttttaaag
    15361 gaaagaaggt agtaagaatg agtgtatctg agataattaa gaaatctgat gcattaatta
    15421 agaaaataaa agatactttt caataaaaat tgatttattt tacatataac tcaaagatgt
    15481 ttttaaagaa atttttatta aaagcatctt tgaaaatatc ttaaaaatag aataaaagga
    15541 gatatagtca tgaaaaagtt accaataaag actgtcgtgc aaagattact aaacttacaa
    15601 gaagagggga aaagtgcaac tcttttagga attggtccta tgtcaccaaa cttgttacaa
    15661 gcaagttttg aactagcaaa agatgatgat tttcctttaa tgtttatcgc aagtagaaat
    15721 caagtagatg cagatgaact aggtggcggt tatgtaaatg gttggaatca ggaaactttt
    15781 acaaaagata ttaagaaggt tgccgacaaa gttggatttg atggtttata ttatttatgt
    15841 agagaccatg gtgggccatg gcaaagagat aaagagagaa atgaccattt gcctgttgat
    15901 gaagcaatgg agttaggaaa aaaatcttat ttagcggaca ttgaagcagg ttttgaccta
    15961 ttgatgattg accctacaaa agacccattt gaaattggaa aagtaattcc actagatgta
    16021 gtactagaaa gaactgtaga attaattgag tattgtgaaa acgagagaaa aagacttaat
    16081 ctaccagaca taggttatga ggttggtaca gaggaaacca atggaggtct gacttcaact
    16141 gagacgtatg aaacatttat aactagacta aaggttgaac tcgataatag aggtttgcca
    16201 atgccaacat ttatagttgg tcaaactggt actttaacta gaaagacaga acaagtagga
    16261 acttttaatt ttagaaatgc ttatgattta gctcaaatgg ctaagaaata tggagttggt
    16321 ttaaaagagc ataatggcga ttacttagat gatgtaactt tattagaaca tataccatct
    16381 caaattattg ctacaaatgt agctcctcaa tatggtactg aagaaactag ggcatattta
    16441 aaattagcag aagttgagtg taaattagaa aaagagggct tagttgagaa aacttctaat
    16501 atcagacatg ttcttcttgt taatgcaatt gaatgtggac gttggagaaa atgggtagta
    16561 ggagaacaaa aaaatctaac tactgaagag atatttaagg atgaagtttt atctaatgaa
    16621 atactagata ttgcaggaca ttatacattt aataatgatg atgttaaaaa agaaatagaa
    16681 gtgctttatg ataatttaag taagaataat attgatggtc aaagatttgt tgtagaccat
    16741 attaaacgtc ctttgcgtga ttatgcagaa tgctataact taaaaggtgt tactacgagg
    16801 attttaaata aataatagga cttatagtgg tgagtattgt tatactaggt atttatagtt
    16861 ataattatac ttaccactat taaatttagg aggactaata ttttgattaa tttaattttt
    16921 gatgtagatg atactttata taatcaatta acgccttttt acactgcata taataaagtg
    16981 ttttcttcaa taaaggatat ttctattgaa gatttatata tgagtagtag aaagtatagt
    17041 gatgaggtat ttcatatgac tgaaaatgga gaaatgccaa tcaaagaaat gcatatttat
    17101 aggataatga aagcttttga ggagttggga aattctatta cagaaaaaga tgcacaaagt
    17161 tttcaagatg agtatatata tcaacaatca caaattacac taataccaga agttgagagg
    17221 attttaaatt tttctaaaga aagaaatatt aatctaggaa ttataactaa tggcccatca
    17281 aaccatcaaa gaatgaagtt aaagcagtta aatattgaaa actgggttga taaaagtaat
    17341 atttttattt ctagtgaggt tggattttct aagccagata ctaatatttt tagagtagct
    17401 gagaatgtta tgaatttaga tagagaaaat acatattatg tgggtgattc ttatagaaat
    17461 gatgtattag gtgctaaaaa agctggttgg aagagtatat ggttgaacca tagaggacat
    17521 gaggtagaag agttgtttta caaacctgat tttgtaattt tggaacataa ggatttgata
    17581 tctttattta taaaaatatg tagttataaa aatatgtagt aaaaaaatgt taataataga
    17641 attgtataaa ataattaata ataactatat aaaattatat gtttagattg tgagcaatct
    17701 attttatgtt aaaaatagat tatttagaag aaggggaaat cttaaaaaaa tttgaatatc
    17761 ccctttttat tatttaatta aaatgaaata gttagaaata tattttattt agtttagtca
    17821 ataacatttt gggattcttt ataactacat gttaactgtt gaataggttt atcatatggt
    17881 ttaacccatc ctttattaat acttaattct gtaagtgctg tgtgaccttc taccatttga
    17941 gttaatgaag ctgaatatat agctcttaat tcaggtgtac tacttgtcaa tgcagaatta
    18001 agatacatat tggcagatgc tttagcagat gaaagcatac ttaacattat tactttatcg
    18061 tctatataag tattgttctt aattagattt tctatcatat ttctcatgtt atctatacct
    18121 cctcagaaat tagtatttca ttttcaacta taaattgttg catagcttta attcttcctt
    18181 ctgttgctaa tatactagat tctgattgtc tttttaggtc ttcatctgat attaacatat
    18241 ttattgctct ttgcataagt aatccgtcag actccatttt tataactgct gctaaagata
    18301 ttttttcagt ttctgaaagt attctcattt aatcatctcc tatattgtaa tttatgcttt
    18361 aatagtatgt ctttcttttc aaggaaataa ccattacact tttttacagt attttatatt
    18421 ctctttatat caaaatttag tcgacctaat atattaataa taattttgta ggatatttat
    18481 cattaaatat ctataaaata aattatttga atattcataa agcaaaattt atttgtatgt
    18541 acttcttcaa gagtcaatat gagttttttc aaaaaattaa tttttatgat aatcattaag
    18601 ggctatattt ttcttaaagt tgtgattatc attattaatt tacaataaaa ttgccgaaaa
    18661 gccctctcct ttaggtgtag ggatgaaagg taaggtctta atataaaaaa agttagaata
    18721 atgcttgtaa tctaataccg ctactgatac cctatattta ggaggtgtta gtttttatgt
    18781 ataaatctaa caaaaatata gtttatgatt gcaaatatca tattgtattt tgccctaagt
    18841 atcgtaaacc tgttttagtt ggcgaagttg aaaagatgtt aaaagaaata ctaccatata
    18901 aagcagatga acttggagca gaaataatag aaatggaaac tgataaagaa catgtgcact
    18961 tattaatatc ttgtgaccct caatatggaa ttcataaagt agtaaaaggt ttaaaaggct
    19021 ttagttcgag agtattaaga gagaactttc cacatttaaa gtctagtatg cctagcatgt
    19081 ggactaatag ctattttgta ggtactgttg gttctgtgag tttagaagta gttaaacaat
    19141 atatagaaaa tcaacaagtt aggacaaaga aatgataaaa actcatagag tgaaattaaa
    19201 cctaactaga acacaatttg aattagtaag ggaaaagcaa atggaaagtg ctaactgttg
    19261 gaactacata gttaacttat ctaaagaata ctattttgaa cataaacaat ggattaaaaa
    19321 gaatgatata caaaagttaa tcaaaggtaa gtacaatctt catagtcaaa ctattcaagc
    19381 tatatcagat aaatttgatg caaatagaaa gactatatca gaattaagaa aaaaaggtaa
    19441 tactaaagca aaatatccat acaagactaa gaaattttat ataatacctt ttaaagctag
    19501 tgctattaat agaaatgcta aaggcaactt aaaattatca atgtcaaaag gcaggtattt
    19561 agaattagat tttaatgttg agaatataaa aactgctgaa atagtatggc gaaatggata
    19621 ttatttatac tacacttttg acaatgaatt aaatggagtt gtagccaaag gcactaatac
    19681 cgtaggtgta gacttagggg aaatacattc gatagctagt gtaacaaatg aaggtgtagg
    19741 gcttattcta tctaatagag aaggcagaag tattaaacaa tttagaaata agatgtatgc
    19801 ttatatatct aaaagattaa gtaaatgtaa aaaaggtagt agacaatcaa agaagttatg
    19861 gagattaaaa aataagataa gaagtaaaac agataatcag ttaatgaatt tatatcatca
    19921 aacaactaga aagtttatag acttttgtgt agagcagaag gtatgtgaaa tagttcttgg
    19981 ggatataaaa ggggttgaaa aagatactaa gaaaaagaaa agattaaaca gagttaatag
    20041 acagaaaata tctcaaatgg agtatggtcg aataaaggac tatataaaat ataaagcaaa
    20101 agagcaaggt attgaagtta agttagttaa agaaaactac acttctcaaa cttgcccaaa
    20161 gtgttctaaa aaacacaaac caactggtag aacttatagt tgtacttgtg gttatgaaac
    20221 tcatagagat atagttggtg cttggaatat tttaaataaa aagcataaat atggtttagt
    20281 agattttaga ataaatcata agcaaccaat aaatttaaaa gtatctaccg tttgagccat
    20341 gtgtgggcga ataactttaa ggtagtagtg gcgaagacac cgtccgaagt agcttggctt
    20401 tgtaaccacc tctgttgtac tgtttaagta taaataagtg tgttagccac caagaatccc
    20461 cttgctttag ctatggggag tgtgtcaata aaatacttta atgaaaaata gctaacttta
    20521 attgtaggat attcttaata tatttgaaat aaataaaaat attgaaggat ataatattca
    20581 attggtatat aaataataaa tgatagttaa attttacctt agaggctaat taggtgttta
    20641 gtcaaagcta atgcctttag aatacaaatg tattctaaag gcatttttac tatgtatttt
    20701 catttatatt actaaacatt atctattttt atatacattt ctatgtattt tattttcatc
    20761 aaatcggtct ataaactcat ttttttcttc actatatcca atagatataa gtgcataagg
    20821 aactaatttt aatggtaagt ctaaagtttg tctaacttta tttaccactt tatttttagg
    20881 aaatactcct gcccaacaag cagctagacc ttgattagta acttctaata ataaattttg
    20941 tgtgcaagca cctaaatctt gtatccattt accaggtttt aagaatttat ctctatttcc
    21001 aagcactact atacataatg gtgcaaattc tatatgcttt gctctatgct gtgactttga
    21061 gagctgtttc agcagttcct tatcatctac tataataaat tcccaaggtt gagcattttt
    21121 tgatgaaggt gcttgcatag ctgattttag tatttcagtt attttatctt cttctatatt
    21181 tttatctata tatgttctta ttgaacgtct attttttata acttctaaca tacagattct
    21241 cctttaaata aaattatttc tatttatata atatcattac tttaaatttt agctattact
    21301 tatataaaga ataaactttg tgttggtttt atctaagtaa aagtaacatt cagaactaaa
    21361 aaacaagact ataaatccaa agtattaatt aaaaaagaag taataaaaaa taatatacaa
    21421 gatttaaaaa agagtattgg gcttaaaatt taattagaaa accaattttg agataatctg
    21481 ttttttattt taacaaaaaa acacaaataa agttcgatac gtagcgaatg aaaaaattac
    21541 aagaaatatt ttttttaaaa aatttcaaaa aagagttgat aatatatgta tattaatata
    21601 aaatttaagg tgtataattc gtataataat acgaatgatt tgtagtgtaa aataacttat
    21661 aaacggagag gggaagtcta atgaaagtag cagtagttat gggttcaaaa tcagattatc
    21721 caaaattaga agaagggata aaactgcttg aaaaatatgg aatagaagtt gtagcaagag
    21781 cattatcagc tcatagaaca ccagaacaac tttcaatatt cctaaaagaa atagaagatg
    21841 atactgatgt aataatagca gcagcaggaa aagcagcaca cttaccaggt gtaatagctt
    21901 cacaaacatt aattcctgta ataggattac ctattaaatc atcaactatg gatggactag
    21961 actcactttt atcaatagtt caaatgccaa aaggaatccc agttgcaaca gttacaatag
    22021 acttaggttt aaacgcagct ttattggcat tacaaataat gactttaaaa tacccaaaat
    22081 taaaagagga tttgaaatca tatagagaag agatggcaca aaaggtgtta gaagacgaca
    22141 agaatttaag ggggtagcag aaatgttatt atatgaagga aaagcaaaac aagtatattc
    22201 tacagataat gaaaatgaat atgttgttta ttataaagat gatgcaacag catttaatgg
    22261 agaaaaaaaa gcagaaatat cttcaaaagg tatactaaat aataagatat caacaataat
    22321 ctttgaaatg ttaaaagaaa ataatataaa tactcacttt ataaaaagtt tatcagatag
    22381 agaaatgtta gttaaaaaag tagagatttt accattagaa gtaatagtaa gaaatattgc
    22441 tgctggttct atctgtaaaa gagttggtct tgaagaaggt gtagttttcg atgagccaat
    22501 ttttgaaata agctacaaaa atgatgctta tggtgaccca atgctaaatg atgattatgc
    22561 agtggcaatg aagttagcaa ctagagaaga gttaaaattc ttaagagaag aaactttaaa
    22621 aataaatgag ttactaaaag catttttctt aaaattaaac ctaaagttag ttgactttaa
    22681 aatagaattt ggtaaggatt ctgaaggaaa tataatattg gcagatgaag tatcaccaga
    22741 cacttgtaga ctttgggatg taaatacaaa tgaaaagtta gataaggaca gatttagaaa
    22801 agaccttgga gaccttgtag aaggttatac ggaagtactt tcaagaatga ataataaata
    22861 ggaggcaaat gtatgtgtgg agttttaggg atttactcta ataaagatgt aactaaagaa
    22921 ctatattatt ctttatattc tatgcaacac agggggcaag aaagctgtgg tttagctctt
    22981 ttagatgatg gagaaattaa gtacaaaaaa gatatgggat tagttggaga tgtttttaag
    23041 gaaaatgaat tatctaagtt aaaaggaaat atagggattg gacatgttag atattcaaca
    23101 gctggaggaa gtcatgtttc taactgtcaa cctttagttg gaagttgtag aaaaagacaa
    23161 ttagccatag ctcataatgg aaatctagtt aatgcaaatt atttaaaaga tatgctagaa
    23221 gaagatggat atatgttcca aactaattca gatacagaag tgattttata tatacttgct
    23281 agatattaca aaggggatat agtagaaagt ttaaaagtga caatggatta tataaaaggt
    23341 gcatatgctc ttgtaataat gagtcaagaa gaattggttg cagttagaga cccacatgga
    23401 ttcagacctc ttgtacttgg taaaaagggt gatgaatata tatttgcatc agaaaattgt
    23461 gcaatagata tacttggcgg agaagttata agagatgtag agccaggaga gataatagta
    23521 gtcaaagatg gagaactaaa atcatatttt tattcagaaa attataaacc agttaagaaa
    23581 agttgtatat ttgaacacat atactttgca agaaatgatg caactataga caatgtaaat
    23641 gcatatgaat ttagaattaa atgtggtgag agattagctc agaatgaaac tgtaaaggca
    23701 gatatggtag ttccagttcc agattcaggt tggccaggag ctattggtta tgcaaatgct
    23761 agtggattaa aaataagtga aggcttagtt aaaaatagat atgtaggaag aacatttata
    23821 aaacctacac aagaagaaag agaaatagca gtaaaaataa aattaaatcc tctttcaaca
    23881 ataataaaag gaaaatctat aattttagta gacgactcaa ttgtaagagg aactacatct
    23941 aaacaattag taaaatcttt aagagaagca ggagcaaaag aaattcatct tagaataact
    24001 tctcctccag tagcttactc ttgttactat ggaatagata ctccaaatcg ctctaaatta
    24061 attgcatcaa gtaacaacgt agaagaaatg agagaatata ttggatgtga tagtttaaaa
    24121 ttcctagata tagaaggaat gttagatgca acagaacata agtctacttt ctgtaaagct
    24181 tgttttgatg gagaataccc agttaagaaa attgataagg aggaactact ttcatgttaa
    24241 catataaaga atcaggtgta gatatagatg aaggaaatag agcagtagac cttataaaag
    24301 gtaaaataaa aggaacttat gatggaaatg tagttggaga tttaggtaac ttcagtggat
    24361 tatacagttt aaaagatttt gtaggtatga aagaaccagt tttgcttgca tctacagatg
    24421 gtgttgggac taagttaaaa atagctcaga tgatggacaa gcatgatact gttggaatag
    24481 atttagttgc aatgtgcgtg aatgatttaa tttgtcaagg agcaaaacca ttattcttcc
    24541 ttgactatat agctcttggg aaattagtgc ctgagcatat cgaaaaaata gttggtggaa
    24601 ttgcagatgg ttgtaaaatg tctggttgtg cactaattgg tggagaaact gctgaaatgc
    24661 ctggaatgta tggagaagat gactatgatt tagcaggatt ttctgtagga atagcagaca
    24721 aagaaaagat tgtttctgga aacaatgtta aatcaggaga tgtattggtt ggtatatctt
    24781 caagtggagt acacagcaat ggattttctt ttataagaaa gatattttta gaaacttaca
    24841 attataaaat ggaacaatat gttgaagaac taggaatgac agttggagaa gcacttttaa
    24901 caccaactaa aatatatgtt aaattagctt tagatgtatt agctaaacat gacataaaag
    24961 ctatagctca cataactggt ggagggctta tagaaaatat aacaagagtt atacctaaag
    25021 ggttaggact agatatcaat aaaaaatctt gggagaagcc tcctatattt aaaatgatag
    25081 aaggttttaa tgctgttgat gagagagaac ttcataagag ttttaacatg ggtattgggc
    25141 tagttttaat agtagataaa gaaaatgctg atgatgttgt aaactttata aataatagag
    25201 aaaatgacaa tgctgcttat gtagataaaa aatatagtga attattagaa gataaagctt
    25261 atataattgg tgaagtagta gatagtcatg aaggtgtaga attatgctaa atataggagt
    25321 tttaatatct ggtggaggaa caaatttaca agcagttata gatggtactg agtctggaga
    25381 aataaaaggt caggttaaag tagttatctc aagtaagcaa ggtgcttatg ggctagagag
    25441 agctaaaaat cataacataa aagcaatttg tgaaactgat gaagacaaga taatagaaat
    25501 tcttaaggaa aataaaatag atttagtagt tttggctggt tatttaaaaa taatcagccc
    25561 aaagctggtt aacgagttta gaaacaaaat gataaacata catccatcat taattccttc
    25621 attttgtgga gctggattct atggagaaaa agttcatcaa ggtgttatag attatggagc
    25681 taaagtaact ggtgctacag ttcattttgt agatgaaggt gctgatactg gaccaatcat
    25741 aatgcaagat gtagttaagg taaatcaaga tgatgatgca aagacacttg caaaaagagt
    25801 gttagaagtt gaacatagga ttttaaaaga aagtataagt cttttttgtg aaaataaatt
    25861 aaaacttcaa ggtaggagag tgtttataaa tgagtaagag agctttaata agtgtaactg
    25921 acaagactgg tgtagtggaa tttgctaaag agttaaataa attagattat gaaattatat
    25981 ctacaggaaa tacatttaaa acattaaaag aaaatggtgt taatgtaatg caagttgaag
    26041 atgttacaaa ttttccagaa atattagatg gaagagtaaa aacattaaat ccatatatac
    26101 atggtggtat actttataaa agagataaag aatctcatgt agaaactgta aatgaacaca
    26161 aaatacattc aatagattta gtagctgtaa atctatatga ttttgaagga actttaaaag
    26221 ctggaaaaag tcatgatgaa ataattgaaa atatagatat tggtggacca tctatgatac
    26281 gttctgctgc caaaaactat aaggatgtaa tagtagtagt agatataaaa gattatgatt
    26341 ctataataga aaaattaaaa acagatacaa tgacattaga agacagaaaa aaattatcat
    26401 ataaagcttt ctcaactaca ggaagatatg atgcgttaat atctagttat tttgctggag
    26461 aagttggaga tacgtatcct gacatattaa atttaacttt ccaaaaagaa caaactttaa
    26521 gatatggaga aaatccacat caaaatggtt tcttatattc acagtcaaat gcaaaaaatc
    26581 caatcttaaa ttatgagcaa ttaggcggta aagaactttc ttttaacaac ttaaatgatt
    26641 tacatggatg tttagaagta atgagagaat ttaaagatag tgaagaagta gtttcagtag
    26701 ctataaaaca tgctaattca tgtggggtag gtttaggaaa agatgctttt gaagcatata
    26761 caaaatgtta tgaagcggat aaggtttcaa tatttggagg aatagtagga ataacttcta
    26821 ctatagataa agctacagca gagaaattaa atgaaatatt cttagaaata gtagtagcat
    26881 atgattttga accagaagct ttagagatac ttaaacaaaa gaaaaatcta agaatattaa
    26941 aattagctaa aatagaaaat agtttacaac catatgaaat gaaatattta gatggaaaat
    27001 tattgataca agatagaaac aatatattag cagaaaaaag tgaaaatgta acaaaggaaa
    27061 aaccaacaga tgcacaactt aaggacatgg aatttggtat gagagtagta aaaaatatga
    27121 aatcaaatgc aattgcagta gtaaaaaatg gacaaactct agctttaggt tgtggacaaa
    27181 catcaagaat ttgggcatta aaaaatgctc ttgaaaataa caaagataaa gattttacag
    27241 gagctgtttt ggcgtcagac gcatttttcc catttgatga ttgtgtaaca ttagctcatg
    27301 aatatggaat atcagcagta gttcaaccag gtggctctat aaaagataaa gattcaatag
    27361 aagcttgtga caagtatgat atggttatgg tatttacagg aataagacac ttcaaacact
    27421 aaggaggata ttatgaagat attggttgta ggcggtggcg gaagagagca tgctatatgc
    27481 tggaaactaa gcaaagaaaa aaatgtagaa aaaatttatt gtgcaccagg taatgcagga
    27541 attgcaaacg tagcagaatg tgtaaatata ggtgatacta atatagaaga acttttaaaa
    27601 tttgccaaag aaaatgaaat aggtctgaca atagtaggac cagaagtacc actagttatg
    27661 ggaatagtag atgagtttga aaaagaagga ttaagagtat ttggacctaa taaaaaatgt
    27721 gctcaacttg aaggaagtaa agctttttca aaagaattta tgataaaaca taacatacct
    27781 actgcaaaat ataaagaata tacaaactta gaagaagcta tatcagaaat agatagtttt
    27841 ggatatccag tagtaataaa agcggacgga ttagctgctg gaaaaggtgt tgtaatacct
    27901 gaaaatagag aagatgctat agcaacttta aaagaaatga tgtcagataa gaagtttgga
    27961 gctgctggag ataaaatagt aattgaagag tttttaaaag gaatagaaac ttcaattcta
    28021 gcatttgtag acaatgatac aatagttcct atggcaagtg caaaagacca taaaaaagta
    28081 aacaactatg agcaaggtcc aaacactgga ggaatgggaa ctttttcacc tagtgaaata
    28141 tatacagaag aattagcaaa taaagtaaaa gagacagtat tagaaaaaac tttagaaggt
    28201 ttcaaaaaag atggacttaa ttttaaaggt attttatttg ttggtcttat gataactgaa
    28261 gatggagaaa aagtacttga atataatgta agatttggag accctgagac acaatctgtt
    28321 ttatttagat tagaaacaga tttacatgag ataatggaag ctatactaga taataagtta
    28381 aaagatatag aaataaacta tagtgatgat gaagctgtat gtgttatgct tacatcagga
    28441 gggtatccag acagttatga aaaagggaaa attataactg gtcttgaaaa cttggatgat
    28501 gatatagtag tattccatag tggcactaag atgtttgatg gtaatttggt taccaatgga
    28561 ggaagagtaa ttggtataac tgcaaagtca actagagtta aggatgcagc agaaaaagtt
    28621 tatgaaaaca taaagaagat aaactttgaa ggaatgcact atagaacaga cataggaaga
    28681 taatttttct aaaatggagg ataaggtatg ttgaatactg aaaataaaga ctcaatggtt
    28741 agaagagtat tggttgaaaa aagagaaggt tttgaccttg aggctaaagc tttaaaaaaa
    28801 gacttagtag aaagtttaca catagataat atagaaaatt taagaatatt aaatagatat
    28861 gatgtagaag gaatatcaga agaagtttat gaaaatgcag caaagacaat attctctgaa
    28921 ccaaatttag atgtagtata ttatgaagaa ataccaaaat taaatgatga aagagtattt
    28981 gcaatagaat ttcttcctgg tcaatacgac caaagaggtg attgggcagc tcaatgtgta
    29041 caaattgtaa atcaagggat aagacctgct attaatacag caaaagttta tatattatca
    29101 ggcaaaataa ctgatgaaga gttttctaaa ataaaagatt actgtataaa tccagtagat
    29161 agtagagaag catctttaga gaaaccagaa acgttaaaaa tggaaactga aataccaaca
    29221 acagttgaag tattagatgg atttatagat ttagatgaaa atggattaag aacatttgta
    29281 agtgaaaaag gattagcaat gactttagga gacttacaac acgttcaaaa atactttaaa
    29341 gatacagaaa agagaaatcc aactataaca gaaataaaag tattagatac ttattggtct
    29401 gatcattgta gacatactac ttttatgact gaaatagaaa atgtaaagat agaagatggt
    29461 aagtttaatg atatagtaaa agaagcgtat caaatgtatc ttaactcaag agacaatgta
    29521 tatgtgaaca gacataaaga tatatgttta atggatatag ccactgttgc agtaaaagaa
    29581 ttaaagaaaa atgggaaatt aaatgaccta gatgaaagtg aagaaataaa tgcatgtagt
    29641 ataaacgtag atgttgaagt tgatggtaag atggaaaaat atctagtaat gtttaaaaat
    29701 gaaactcaca accatccaac tgaaatagaa ccatttggtg gagcagctac ttgtttagga
    29761 ggagctataa gagacccatt atcaggaaga agttatgttt atcaagcaat gcgtgttaca
    29821 ggaagtgctg acccaagaac gactttagaa gatactttac ctggaaaact tatgcaaaga
    29881 aaaataacta cagaagctgc tcatggatat agttcatatg gtaaccaaat aggtcttaca
    29941 actggacaag ttgcagaagt atatgatgaa aactttgttg caaagagaat ggaaataggt
    30001 gcagttatag cagcagcacc aaaagagaat gtagtaagag aaagacctga agcaggagat
    30061 gtaatcgttc ttcttggagg aaaaacagga agagatggct gtggaggagc aactggttca
    30121 tctaaagaac atagtgaaga gtcaatctta acttgtagtg cagaagttca aaaaggagat
    30181 gctcctaacg aaagaaaaat acaaagattc tttagaaata aagaagttgc tcaaatgata
    30241 aaaagatgta atgattttgg agcaggtgga gtttgtgttg ctataggaga gattgctgat
    30301 agcttagata taaacttaga cttagttcct aaaaaatatg atggacttga tggaactgag
    30361 cttgcaattt cagagtcaca agagcgtatg gcagtagcca taaaaaaaga aaataaagat
    30421 aaatttatac aattagcagt agaagaaaac ttagaagcta cgcatgtagc tacagtaaca
    30481 gatacaggat atttaagaat gttctggaat ggaaaagcaa ttgtagatat aaatagagag
    30541 tttttagata caaacggagt aaaacaaact actgatgttc atgttactaa agtagatgaa
    30601 gaaaatacat tctttagctc taatgaaata gtaaaagatg ttaagtgtgc aagtatgaaa
    30661 gacaagttta caaaagtact atctgacctt aatgtttgtt ctcaaaaagg attagtagag
    30721 atgtttgata atacaattgg tggtaataca gtacttatgc catttggagg aaagtatcaa
    30781 gcgactccaa cacaaggtat ggttgctaag ataccagtac ttggaggaga aactaatact
    30841 tctacaataa tgacttatgg atacaatcca aaggtaggaa aatggagccc attccatggt
    30901 gccttgtatg cagtagtaga atctgtgtgt aaattggttg ctattggagg aaattatagt
    30961 acaacaagac ttacattcca agagtatttt gaaaaacttg gtaacaatcc agaaaaatgg
    31021 ggtaaaccat tctcagcact tttaggagcg ttttatgcac aaagtaaatt tgagatacct
    31081 gctataggtg gaaaagacag tatgtctggt acatttaaag atattgaagt tccaccaaca
    31141 ttagtttcat ttgctgttga cacagtagat gcgaagaaag tagtatctcc agaatttaaa
    31201 aaagcagact caaaagtagt aatgttatgt gtaaacaagg cagaaaatga tgttgtagat
    31261 tttgaggaat taaagagaaa cttagataaa gtaagagaac ttatacatgg aaataaagtt
    31321 ttatcaacat atgcattagg atttgcaggt gtaggtgaag caataagtaa aatggctttt
    31381 ggtaataaaa taggatttaa gtttagtgaa gaagctgaaa aagcatttac agataataaa
    31441 ttatttgagg ctagttatgg aaatatagta cttgaattag caaatgatga tttaagtatg
    31501 ttagaaggat acaattatgt tgtgattgga agtacagtta aagaagctag tatatttatc
    31561 aaaggtgaag aacttgcatt agatgaatta tataaagcac attgtagtac tttagagcct
    31621 atattcccaa ctaaaacaga agaagtaaaa tcaaagatag aaactataag ttatatatca
    31681 caaggagaag ctaaaaaatc atcattaagt atagctactc caagagtatt tataccagca
    31741 ttccctggaa caaactgtga atatgactct gcaagagcat ttgaaagagc aggagctaat
    31801 gcaagtataa gagtatttaa gaatttaact tataaagaca tagaagattc tatagataca
    31861 atagtaaacg aaataaaatc ttctcaaata ataatgttac caggtggatt tagtgctggt
    31921 gatgagccag atggttctgg taaatttata gctactgtat ttagaaatcc tagagtgcaa
    31981 gaagctataa atgaattttt aactcaaaaa gatggactaa tgttaggtat ctgtaatgga
    32041 ttccaagtat taattaaatt agggttagtt ccatatggag aaataagagt tccaagtgaa
    32101 agtgctccaa cacttactta caataatatt ggtcgccatc aagctaagat tgctagaact
    32161 agaatttcat ctaataaatc tccttggtta gctcaaacta atgttggaga tattcataat
    32221 atagcaattt ctcatggaga aggtaagttt gttgccagtg aagatgttat gagagaatta
    32281 attgctaatg gacaagtagc aactcaatat gttgacttta ataatgaagc tacttatgat
    32341 attgagttta atccaaatgg ttcattctat gctgttgaag gtataactag tgctgatggt
    32401 agagtgtttg gtaaaatggg acattctgaa agaattggtg aggaagtata taagaatatt
    32461 ataggtgaaa aagaccaaaa gatatttgaa tctggagtta aatattttag ataaagcttt
    32521 gatgtttaat tgatagctag aatatataat ttagatattt agatttaaag agatgtaata
    32581 atatgatgat aatcatttaa tattacatct cttttttatt tatctaagaa ataataagtt
    32641 caacctaagt taaaatacaa gctgtgttat aattaattat taagtaaaat tgaatattta
    32701 ttggagggca acataattaa tgaaaatatt aataacaggg tctaatggtc aattaggaaa
    32761 agaattggtt aaccaattag aagcaatcaa tcaaagtata aaccaaccaa aatatgttat
    32821 attagctaca acaagaagtg atttggacat atccaatcag actaatgtag ataattttat
    32881 tttgcataat aaacctgatg tagttgtaaa ctgtgcagca tatacaaagg ttgatgcatg
    32941 tgaagataat atcgaaattg catacaaaat aaatgcttta ggagtgagaa atctagcaat
    33001 agcatcagaa aaagttaatg ctaagcttat tcacatatca actgactatg tattcaatgg
    33061 tttttctaaa tatccatata gggaagacaa taaaactgaa cccaattctg tatatggaaa
    33121 aagtaaactt atgggagaaa aatttgttga acaattctca cataagtact ttatattgag
    33181 aacagcatgg ttatatggta atgggaataa ttttgtaaag accatgataa aactttcttt
    33241 agaaaataaa gaggttaatg tggttaatga ccagtttgga actccaacaa gtacagtaga
    33301 cttagcaaaa attataataa gaatcatgga aacagaacat tatggagttt atcatgctac
    33361 atgtgaaggt gagtgtagtt ggtatgattt tgccaaaaag atatttaaac taaaaaatat
    33421 agatataaaa gtaaatccaa ttaagagtaa cgaatttaaa tgtaaggctc caagaccact
    33481 atattctgta ttggataatt ttatgttgaa gttaattggt ttaaattctt ttagaaagtg
    33541 ggaagaatcc attgaagaat atttagaaag atatgatata aatgaaaagt aaatgtatta
    33601 ttttgagaaa agaaaataag atattataaa aaatataaat atttctttta tttatccgat
    33661 aatcataata tgacaaaaac aaatttaagg atggaaaaag atgaaaggaa ttattttagc
    33721 aggagggtct ggtacaagac tatatcctat aacaaaatgt atatcaaaac aaacacttcc
    33781 aatatacgat aaaccaatga tatattaccc tatgtcggtt cttatgttgg cagggataca
    33841 agatatatta ataatatcta caccaagaga tataaaagca tttgaagaat tatttggaga
    33901 tggaagttca ctagggctta acataacata tgcaattcag gagaaagcaa atggaattgc
    33961 agaagcgttt ataataggag aagaatttat aggaaatgac agagtgtctc ttgtattagg
    34021 ggataatata ttttatggat atggatttag tgaaaggttg gagaatgcag ttaaaagaaa
    34081 aggagcaact atatttgggt atcatgtaag taatccaaat tcgtttggag ttgtagaatt
    34141 tgataaggat tttaatgtat tgtcaataga agaaaaacct acagttccta aatctaatta
    34201 tgctatacca ggattatatt tttatgataa tgatgttgta gagatagcaa agctagttga
    34261 accgtcagat agaggtgaat tagaaataac ctctataaac agtgaatatc taaaacgagg
    34321 aaaactaaaa gtggaacttc taggaagagg tatggcttgg cttgatactg gtacacataa
    34381 aggtctattg gatgcttcta attatgttga agtggttcaa acaagacagg gactgtatat
    34441 agcatgttta gaagagattg catatacaaa aggatatata agtagagaac aattaatgaa
    34501 actagccaag ccactgataa aaactgaata tggtcaatat ctattaaaat tggctagtga
    34561 agatatgtaa tatggtagat aaaatttatt ataaatttta ttaagggagt ttattataat
    34621 gggaaaaatc aatgttataa agactaaaat agaaggatta tatatagtcg aaccaaatgt
    34681 attttatgat gaaagaggat attttatgga aagctataat aaaaaggatt ttatagagca
    34741 gggtcttgat atgtgtttta ttcaagataa tgagtctagc tcaagaaaag gcgttttaag
    34801 aggaatgcat tttcaggtta aatatcctca aggaaaatta gtcagagtta cagagggaga
    34861 agttttcgat gttgcagttg atttaaggaa agattcacaa acatttggga aatgggaagg
    34921 tgtaatattg tctgataaga ataaaaaaca attttatatt ccagaagggt ttgcacatgg
    34981 atttttagtt ttatcagaaa aagcagtatt tagttacaaa tgtacaaatt attattaccc
    35041 agaatttgag aatggcttta tatggaatga caagcaaata tctattgagt ggcctttaaa
    35101 aggaattgaa gaaatatttt tatcagaaaa ggacaaaaaa caaaaaagtt ttaaagatat
    35161 ttgtacaaga cgttaataaa aatttattag aattaacatt taggagaaaa aatatgaaaa
    35221 aaatactgat aactggagga gcaggattta ttgggagtaa ttttatacat tatatgctta
    35281 acaagtatgt agattatttt attgttaacc tagacttgtt gacttatgct ggtaatttag
    35341 agacattaat agaaatacaa gacaattcca attataaatt tgttaaagga gatatttcaa
    35401 atagggagca ggtgtataag ctatttgaag aagaaaggtt tgatatagtt gttaactttg
    35461 ccgctgaatc tcatgtagat aggtcagttg agaatcctga tttatttatt aaaacaaaca
    35521 ttataggaac acaagtactt ttagatgcat ctataaaata tggagttaaa aggtatcatc
    35581 aaatatctac agacgaagtg tatggtgatt taccaattga tagaaaggat ttattcttta
    35641 cagaacaatc ttctatcaat ccaagttctc catattcagc ttctaaagca tcagcagatt
    35701 tattggtaag ttcttattat agaacatatg gattgttaac aactatatct aggtgttcca
    35761 acaattatgg gccatatcat tttcctgaaa aattgattcc tcttatgatt ttaaatgctt
    35821 tggaaaacaa acaattgcca gtatatggga atggggaaaa tgtaagagat tggttacatg
    35881 tatatgacca ttgtactgct atagacttaa taatacataa aggaaatata ggggagattt
    35941 acaatatagg aggtcataat gaaagaagta atctagaagt agtaaaaatg atattaaatc
    36001 ttttaggtaa atctgaagag ttaatatcct atgtaaatga tagacctggt catgatttaa
    36061 gatatgctat tgatgcaact aaaatagaga atgagttagg ttggaaggca aaatatgact
    36121 ttgatttggg tataaaagaa actgttaagt ggtatataga aaatgaatct tggtggaaag
    36181 ctgttttatc agtataactt taaaatttag aaaggggcgt tttatattga atgagataag
    36241 ttcactaatt aatatattag cattgactca attatctggt agtaatacta caaatcaatg
    36301 taattgtaca tataataatt catctggatt tgatatgatt atgatgacct tgttaaaagc
    36361 attatcacaa aataatcaac atacttctaa tagctacaat ttattgtcta attctgagaa
    36421 tttatttaat gaacttgata atgtagtaaa taataccact agtagattta tagatgttga
    36481 tacaaaagat aaaaatgtaa agttgagaat tgaaaatgct gtagatcaag catcaaaaaa
    36541 atataacgta gattcaaatc ttataaaagc aataattaaa gttgaatcag attttaatcc
    36601 aaataccgtt tcttctgctg gtgctaaggg tcttatgcaa cttatgccag aaaactgcag
    36661 agacttagga gttacagacc cttttaatat agaacagaat atagatgctg gaactagaca
    36721 tattaaggaa tacattgata tgtttggagg gagcatagaa atgggattga tggcatataa
    36781 tggtggtcct ggaagaatga aaagtagagg agtagaatca atctctgacc tgtataaaat
    36841 gccaaaagaa acacaaaatt atattcctaa ggttatgaaa tattatagag ggtaggcttt
    36901 attatgggaa taaatataga taagctaaac ataagtccaa gtataaatat ggaggttaaa
    36961 aaactaaaag agagtaataa attttctgac aaattaaact ctttaaaaca atcttcttca
    37021 ttggaagata taaaacgaaa tttggaaagt gtaaaaaagg caggagaaag gcttgtactt
    37081 actcaaaact atggcgatat tagtatatat aaaaatgcag taaaagaata cctaaaatct
    37141 gttgtagata atatgtattc acttgataaa aatagtagct tttgggagca tcagtattat
    37201 aagaatgtaa agattgttga tagtaaactt gaggatatga ctagtaagtt aattagtgaa
    37261 gaaaaagaaa acatagatat tgtttctact gttgacatga tacaaggctt attgatagat
    37321 atgtatagat aaggttatac aaggagaaaa attttatgaa tagcaaaaaa gaggatatat
    37381 atgaattgaa ttttgggcaa ttaatagaag aaaaatctgg tgttatagaa gaaaatcaaa
    37441 atgtttttaa tgcaaaagta aatgtagctg tttctatagg aaatacaaca gaaacaataa
    37501 aaaatatatt agatttaaaa gaaggctcta taataaaatt aagtaagaat gtggatgaaa
    37561 aattagatat atatgcaaac gatagattgt ttgcttatgg agaaagcatt attacaaatg
    37621 agaggttatc tgtaagatta tctaaaatag aagatccaga tgtaaattag cattttaaat
    37681 agtatccctt taggctattc tgtatgagtt tagctaaggg gatattttta taaaaaattt
    37741 aaaatatgtg tgaattatat aaatattttt attttatgag cgataactaa attataagta
    37801 tgtaattttg gaggtgaaac tatggatatt aaaaatgtaa gttcaaatat tgtagtgaat
    37861 aattatttaa agaatacatc tggtataaaa aaagtggaag aggttaaaaa aattaataaa
    37921 acagataaga tagagttatc taaatttgca aaggaaatgg caagtgtgtc aaatatgagt
    37981 gatgagaata ttagaaataa aaaagtcgat gaaataaaaa atgcattaga aaatggaact
    38041 tacaaaataa aaccaaaaga aattgcgaaa aaaatgatag aggatatgcg aggataaagt
    38101 catgattaca gacttaaaag ttataatata tgaagaaaaa aatataatta gtaagatgat
    38161 ggaattatta aaagaacaat ttgattatat agttgaaaaa gacttagaaa atttaaatat
    38221 gttaaatcct aaactagaag atattagcag ggagcttgca tccatagaaa taaagagaag
    38281 acaacttttt ggtgatgata tttcaatgag tgaagttgtt gaaaatagta atgatggata
    38341 cttaaaagaa atatatacag acttgaaaca cattcttgct ttagctaaaa atcaacaaga
    38401 atcaaatgat tctctaataa agaaagaact tatttttacg aaaaaaatga ttaatttcat
    38461 aaaaccagct gataagcaaa ctacaactta taattcttat ggaaatatta gaaaataaat
    38521 attaggagga gaaatatggc aggattattt tccattttaa atacagctaa ttcaggaatg
    38581 aatgcgcacc aaaaagcaat acagacaatt tctcataata taagtaatct agatacagac
    38641 ggttattcta ggcaaaggac cgagtttgcc acaaatagtc caatgtatat gcctagtttg
    38701 agtaattcaa ttgcaagagg acaattaggg actggagtac atgtaacgga tgtaacaaga
    38761 gctagaaata gtttttatga ttaccaattt agggcagaag ctcataagta tggtaagaca
    38821 gtttcaaaat atgattatta caatactata gaaactatac taaatgaacc atcagactat
    38881 ggaatatctg caggtataga tgattttttt aaaggatggg agtcattatc aaaggatata
    38941 aatagtgaca gtaaaaaaag tctagtggta gaaaacgcat ctaatttagc aactttaata
    39001 agtgaaagtt ataagaagct tgataagtta aaagaagata tagattctaa tatagacact
    39061 gagataaaac aaataaatga catgttaaaa agtcttgaag atttaaataa atctattgat
    39121 attatatctg gttctggctc tacaccaaat gatttacttg atgaaagaga tagaatttta
    39181 gataacttga gttttaaact agactttgaa aatagtgatg ttaaaaatat gcttgcagat
    39241 ggtaaattag aacttaatga attaaaaaat ccagatggaa cttggaaaac aggtatatca
    39301 gggaccttac aaggcttgtt tgaaatgcat ggtaagattg atacatataa aagcgattta
    39361 aaagatgtat ctgatggatt agctaaacag ataaatgatg tttataatac gtctgcagga
    39421 ataacagtaa cagatttttt tataacttca aatgtagatg gtgaagatat tataaagata
    39481 aatccagcta taaagagtaa cccaaatgaa ttaaagctta ctgctgatga agcttcaaaa
    39541 attgctaagt taaaggatga aaaaatagat attggggtgg ctggtggaaa agtaagtaca
    39601 ataagtgacc actataaagc ctttgcagaa tcaatcggtt tagattctca aaaagtaaat
    39661 caagatgaag caaatcaacg taaaattata aataatattg ataactcaag aatgagtgtt
    39721 tcaggtgtat ctttggatga agaaatgaca gagcttataa aaatacaacg ttcatatcaa
    39781 gctagtgcaa aagttatgtc aacagctgtg caactactgg atgttgtaat aaatggaata
    39841 atttaataga agggggaatt tataatgaga gtcagtacag gtatgatgtc tagcagctat
    39901 ctaaactcac tacaagataa tctacaaaga ttggataagg ttaatagaca agttaataca
    39961 acaaaagaaa taaacaagct atcagataat ccatataaag caataaagat attaaactca
    40021 aaaagtgaaa taaagactat ggagacttat gttgagaatt gtaaagatac agggaattgg
    40081 ttagaaacta ctgatactgc attagatcag cttggaaaat tattatcaga cataaagaaa
    40141 actttggtgg caagtggtga tggtgcatac tcagatgatg aattaaagac tcttagtaat
    40201 gaaactaatg aaaaaatgaa agaaattgca aatgctttaa atgcaacaca tgaagggaag
    40261 tacatatttt caggttcaaa tacgggggta ccacctgttg aatgtataga taatgctgat
    40321 ggttcagtga gtttaaagtt taattctagt ctaaatctta ataaattaaa tgactctttg
    40381 agtatggata tagctcaagg aataagtgta gattataacg ttaaattgag tagccttgga
    40441 tttgacccaa caaaaactga cccatttgaa gagttaaata acatatcaaa aaaattagca
    40501 aatccagatg ctgatgctat aaaagagctt acaacaactt gtttgggcga tatggaacaa
    40561 ctaatagaaa atacagtaaa tgttaggtct atatatggga caaaagcaaa tacagtagag
    40621 gctatgaagg aaaaaaacga tgatagtttg atacagttaa aggatatttt gtcacaaaat
    40681 gaagaaatag attatggtga aaaacttgtt caattaaagg cagcagagtt aacttatcaa
    40741 gcttcactac aaacaggagg aaagttattt aatgtatcta tattagatta catataataa
    40801 aataacgcag atatgatgaa ggttacatta aaaaaaggta tattaggttt tgaaaattta
    40861 aaagaatatg agcttttaga tatagaagat aatgattatt taaaagaatt taattctact
    40921 gaagaagaag gtataggatt tgttgttgta tctccatttg agattatcaa tgaatatgaa
    40981 atagttttaa atcaggaaac aatagaaaaa ctagaagtga aatctccaaa ggatgttgta
    41041 ttatttaata taattactct tggtcagaca tttgaagaat caactgtgaa catgaaagct
    41101 cctatagtga taaatataaa aactaatttt ggaatgcaaa taattttaca ggatgataaa
    41161 tattcaataa ggcatccatt attgagaggt gatagtggat gctagtaatt tcaagaaaaa
    41221 aagatgaagc agtacttata ggagaaagca tagaagtaaa aattgtaggg gtagatggaa
    41281 acaatgtgaa actagctata tcagcgccta acaatataag tatattaaga aaagaaatat
    41341 acgaaaaagt aaagagtgag aatataaaag ctacaaataa aaatataaaa attttaaagt
    41401 cattaaaata ataagcttgg aggaagtaat atatgtatgg agaaaatcct tataattctt
    41461 ataaacaaaa tgctgttttt atggcatcaa aggaacaatt gttacttatg cttgttgatg
    41521 gagcagtaaa atataccaaa atagccaaaa cagctatctt agataaaaat acacaaaaag
    41581 cgcatagaga gcttataaga gttcaggata tatttacaga actaatggtt acattagacc
    41641 aaaatgcagg tcaatgggca aaggatatgt acagagttta tgattttgta agatatgaac
    41701 tttcaagagc taatattaga aaagacattc aaataataga taatgtgttg cctgtaatag
    41761 aacaaattaa agatacttgg catgaagctg ataaaaaaag taaagaagaa agaagtaggt
    41821 acaaataatg gaattaaatt tagctgaatt agataagtta tcaaaagagg aattactatt
    41881 gatgcttgta gatggaacag taaaatatac caatatatcc aaagaagctc ttttaaataa
    41941 cgactatttg aaagcacata atgaacttgt aagagttcaa aatatattta cagaactaat
    42001 gactacatta gaccaagatg caggtcaatg ggcaaaggat atgtataaag tttatgaatt
    42061 tataaaatct gaattagcaa tagctgatga aaataaagat attaaaataa ttgatgatat
    42121 attgccaata gtaaaacaaa ttagagatac atggcatgaa gtttacaatc aactaaaaat
    42181 ataattggat ggagggataa aggtatgtca agtataagtc ctataagagt tacaggtctt
    42241 tcaggaaatt ttgatatgga aggcataatc gaagctagta tgattagaga caaggaaaaa
    42301 gttgataaag caaaacaaga acaacaaatc gttaaatgga agcaagaaat atatagaaat
    42361 gttatacaag aatcaaaaga tctttatgat aaatatctaa gcgtaaattc tcctaatagt
    42421 atagtaagtg aaaaagcata ctcttctaca agaataacca gttctgatga aagtattata
    42481 gtagcaaaag gctcagctgg tgcagaaaaa ataaattatc aatttgcagt ttctcaaatg
    42541 gctgaaccag caaaatttac tattaaatta aattcaagtg aacctattgt tcaacagttt
    42601 cctccaaatg ctagtggagc gagttcttta actataggag atgtaaatat accaatatct
    42661 gaacaagata ctacaagtac tattgtaagt aagataaact ccctttgcgc agataatgat
    42721 ataaaggctt cttatagtga gatgacaggt gaattgatta tttcaagaaa acagactggt
    42781 tcgtcatcag acattaattt aagagtaatt ggaaatgaca atttagctca gcaaattgct
    42841 aatgataatg gtatcacatt tataaatgat gctggtggaa acaaagtggc aaatgtatat
    42901 ggaaagaatc tagaagctga tgtaactgat gaacatggaa gagtaactca tataagtaaa
    42961 gaacaaaatt catttaatat agataatatt gactataatg taaattcaaa aggaactgca
    43021 aagttgactt ctgtcactga tactgaagaa gctgttaaaa atatgcaagc atttgtggat
    43081 gattataata aactgatgga caaggtctat ggtttagtta ctactaaaaa accaaaagat
    43141 tatccgcctc ttacagatgc ccaaaaagaa gatatgacaa ctgaagaaat agaaaaatgg
    43201 gaaaagaaag ctaaagaagg tatacttaga aatgatgatg agttaagagg ttttgttgaa
    43261 gatattcaat ctgcattttt tggagatgga aaaaatatta ttgcattaag aaaactaggt
    43321 atcaatgaaa gtgaaaatta caataaaaaa ggtcaaatat catttaatgc agatactttt
    43381 tcaaaggctc ttatagatga tagtgataag gtatacaaaa cactagcagg ttattcttcg
    43441 aattatgatg ataagggaat gtttgaaaag ctaaaagata ttgtatatga atattctgga
    43501 agttcaactt ctaaacttcc taaaaaagca ggtatagaaa aaactgcttc tgctagtgaa
    43561 aatgtatatt caaaacaaat tgcagagcaa gaaagaaata taagcaggtt agttgaaaaa
    43621 atgaatgata aagagaaaag actttatgct aaatattcag ccttagaatc tttgttgaat
    43681 cagtattctt cccaaatgaa ttatttctca caagcacagg gtaattaatt atggataaat
    43741 taaaagaaaa attaaattta tataaagata tatctttaca aattataaat ttgattgaaa
    43801 aggaagaata tataaagata agtattaagt taggtgaaag acaagagatt ataaatagtg
    43861 taagtgaaat tgatagaaat gattttatac agctttataa tagaatggaa ttaattgaaa
    43921 ttgatagcag gataagagat attttacaag gacaattatt agaagtaaaa aaagaattac
    43981 atgagtataa gcttactaaa caagtgaaca caatgtatta taacttaaat agagaaaaag
    44041 taaatatttt taataaaaaa gtataaagtt atgtaccatc ttgtccgatt atataaatga
    44101 agaattaata aaaaagatta aaagtagaaa tgacaaggat gtcaactata ctaaggaggg
    44161 taaaataatg agagttaata caaatgtaag tgctttgata gcaaataacc aaatgggaag
    44221 aaacgtaaat gcacaaagta agtctatgga gaagctatct tctggtgtta gaattaagag
    44281 agctgctgac gatgctgctg ggcttgctat atctgagaaa atgagagctc aaataaaagg
    44341 tttagaccaa gcaggaagaa acgttcaaga tggtatatct gttgtacaaa cagcagaagg
    44401 tgcattagaa gaaactggta acatactaca aagaatgaga actttatcag tacaatcttc
    44461 aaatgaaact aatactgctg aagaaagaca aaagatagct gatgagttac tacaattaaa
    44521 agatgaagtt gaaagaatat caagctcaat tgagtttaat ggtaagaaat tacttgatgg
    44581 aagttctaca gaaataagat tacaagttgg agcaaacttt ggaacaaatg ttgcaggaac
    44641 atctaacaac aacaatgaaa taaaagttgc tctagtaaat acttcaagta taatgagtaa
    44701 agcaggtata acaagttcta caatagcaag cttaaatgca gatggaactt ctggaacaaa
    44761 tgcagctaaa caaatggtat ctagcttaga tgtagctctt aaagaattaa atacatcaag
    44821 agcaaaatta ggggcacaac aaaatagact agaatcaact caaaacaact taaataatac
    44881 tatagaaaat gttacagcag ctgaatcaag aataagagat acagatgttg cttcagaaat
    44941 ggttaactta tctaaaatga atatattagt tcaagcatca cagtcaatgc ttgctcaagc
    45001 taatcaacaa ccacaaggag ttttacaatt attaggataa aataattttg tatattggat
    45061 atagaagaaa gggtaaggct ttgctttact cctttctttt tttacaaata tacttttgaa
    45121 aggaaaattt atatgttact tagtatagtt atgattgtta aaaatgaaga aaaaatactt
    45181 gaaaaaactt taaaatcatt aaccacatta agaaattcta tagaaagtga acttataata
    45241 gtcgatacag gttctacaga tgatactata aaaatatcta agaagtacac ggaaaaagtg
    45301 tattttcata attggaataa tgatttttct agtatgagaa atatatcaat atcctatgct
    45361 aaaggtgaat ggttacttat attagatgca gatgaaatac taattgattc ttcaactatt
    45421 gtaaaatttt ttaaagatgg tcttgataaa aaatttaatt ctgcttcaat acaattaaaa
    45481 aatctttact catatgataa aaaattatat ggatattgtt cagtgcttag actttttaaa
    45541 aacgttgatt ttagatacca tggtaaagta catgaacaac caatatacaa aaaccctata
    45601 tttaataatg ttgctgattt tgaacattat ggatatttgt ttgaagatga agaaataaga
    45661 ttaaataagg tgaaaagaaa tgaaaaacta ttatttcaag agttaaaaga gaatgataat
    45721 tctccatata caaactatca attagggaaa aattttatta tattaggaaa atatcaggag
    45781 gctttatact atcttgagaa atcttatgaa ttatattcta aactagaatt ggcacctggt
    45841 tacttgataa caagccttgt aaaaacatat ttatatttag gaaaacataa gaagtgtgaa
    45901 agattgtgct taaagtatat taagaaagac atgaataata ttgatatata ttattatatt
    45961 gcacaagcac aagtagattt aggaaagtat gaaaatagta tagattcgta taagagatat
    46021 atttacttgt tagataatta tgaaataagt acacaagcaa atagtttatt ttcagacact
    46081 gatactgtag ggcttagaga tgaggctatt attacactga taaagattta ttataagctt
    46141 gaaaaatatg agtttgtaat ttcagagtat aataacattg aagatgtgga aaagaaaaag
    46201 aatgtgtact ttagcttatt tatgtcacta tataaattga atagatttga agatataaaa
    46261 aattattata aagaagtttc aaattctaaa attgaaaaaa atagttttta tagaaatata
    46321 gaagaagtta taaataatat taaagaggat gaaaaagagt atgtatataa aatcctttgt
    46381 gacattgaag gtaattatgg cattttaaat caaataagga taaataaatg tgtatctata
    46441 gataaatgta aagaaatact caatgaagaa aaggaaataa tttatgcata tattataaaa
    46501 atagcttttg aagagaagat tgatttacta gatatttttt atgaaatgga atatgtatgg
    46561 atagagaaat atctaaaata tcttttagca ttagaaagaa gttttaattt agtactatat
    46621 aagtacataa ttagtcgtcc aaatacatca gatatggaaa agataagagt atataaagct
    46681 atatctaaag tagttttaga aagtataagc ttaagtgatg aaaaatataa ggagattttt
    46741 tatctttata taatgtattc ttataagtac ataagataca tatatagcaa tttaagtgat
    46801 tttgaattaa taaaatttgt ttgtaatgat ttagataagt tcactataga atttaagcat
    46861 ctacttgata ttaaaaataa agtaaataat gctaatgaaa aattagagta tatacatagt
    46921 atgaggaaat tactaaatga gtatcctttt tataataaaa taataaaaat acttataggt
    46981 gaattagaag aaaatataaa agaaagtgaa gaatttaagg atttaaaaga tagttttatt
    47041 attagtatag aaaatatgat tgaaactggc aaaataaatg atgcgaaatt attggtagat
    47101 gactattcaa aaacatttgt ggatgatata aagattttaa atataaaggg aattttatac
    47161 atgtttgaaa ataagcttga taaagctgat tttatgttaa aaaaggcatt atcattagat
    47221 gtagaaaatg aagatactat atataatata gaatacttaa aaagtttaag ataagtcaaa
    47281 aataggagaa ttgaagaatg aatataccaa tagtggttaa tgaaaaatct aaagacataa
    47341 taaaagattg gcaatataca tgtacaaatg aagatataaa atttacaagc ataataatat
    47401 tgacatataa tcaaatagaa tatactaaat tatgtattga aagtattagg aaatttaccc
    47461 caaagaataa atatgaaata ataataattg ataataactc ttctgatgga acagttgagt
    47521 ggttaaaggg acaatctgat ataaaatctg tgtataataa caaaaactta ggatttccaa
    47581 aaggatgcaa tcaaggtatt gagttagcta ctggtgaaaa catattgttg ttaaataatg
    47641 atgtaatagt tactccaaat tggctctata atttgaataa agctttatgg tctcaagata
    47701 atataggtgc tgtaggacct attacgaatg catgttcata ttatcagcaa attgatgttg
    47761 attataagtc aattgaggac atgtttatat ttgcacacaa aataaataaa tctaatatta
    47821 acctatggaa atatagattg aagttagttg gattttgcat gttaataaaa aaaactgttc
    47881 tggataatgt aggggtttta gatgaattat tcacacctgg aaattttgaa gatgatgatt
    47941 tatcttttag gatgatagag tcaggatata agttattatt atgccaggat acttttatac
    48001 accattttgg aagtgtgtct tttaaagaaa atcgtaataa atatacagat ataatgtata
    48061 ttaatagaag aaaatttgaa actaagtggg gatttaatcc agaatatagt ggaatgataa
    48121 gaacagattt gatttctaaa atagatgata gtttggaggc aaatattaat gttttagaaa
    48181 taggatgcgg tataggggct actcttttag aaataaaaaa tatatataaa aatgcatcaa
    48241 tatatggaat agaaattagt gagtcagcag gtaaacttgc aaagtatagt gcagatgtac
    48301 ttatagcaaa tatagaaaaa gtaaaattgg attataaaaa agattttttt gattatataa
    48361 tattgggaga tgtacttgaa catttgattg acccatggaa gatagtcaat gaattgaaac
    48421 aatatctaaa gaaggatggt tatctggtat ctagtatacc aaatattatg catgtttctg
    48481 ttttaagaaa tcttgtgtta ggtaatttta catatgaaga ttcaggaatt ttggacaaga
    48541 ctcatttaag gttttttaca ttaaatgaga taacaaaaat gtttaatgat agtaattaca
    48601 taattaatag tattacagct actagtatgc cactttcgga aattgataat agcttcattg
    48661 atacaatatg taaggaaagc tgtaaagaaa tgagacaaca gtacgaatct tatcaatata
    48721 tagtaaaagc ctctaaaatc ctagatacta aaagatattc tagtattagt atgattaatt
    48781 taaaatacgc tttaatgaga attgataatg aattagatgt agatagtaat ttaagttata
    48841 tatttgataa ttataatata actgaaccat gttttgttga tgatattgaa tatctaattg
    48901 atacatttgt gataaataaa gcaactctat taaatagatt aggagttgag gcatttaaca
    48961 gaggtctagg agattttagt ataaacatgt ttatgacagt attagagatg gatagagatg
    49021 atattgactc aatatataat ataacaagtg tattatgtga attagaagaa tttgatactg
    49081 cttataattt aattaaaaat agtagcgaaa aagtacagag tgaaagtgat atacaagaga
    49141 tactttgttt tattgagggg aagaaatatg aataatgata agatatgttt tataacctgt
    49201 gtaaatgatg aaaggcttta tgaagaatgt cttgtatata taaatagcct agacattcct
    49261 aaaaacttta gtatagaaac agtagcttta agaggagccg attctattgc ctctgcttat
    49321 aataaagcta tgagagaaac agattctaag tataaggtat acttacatca agatactttt
    49381 ataattaata aaaatttcat acatgatatt ttagagatat ttaaaaaaaa tacagatgtc
    49441 ggaatgattg gtgtagctgg agtaaaagat atgcctgtga atggaatttg gtgggattct
    49501 gataaaaaag cagggaaagt atatgatagt catacaggta aaatggatat ttatgaattt
    49561 agtaactttg aagaatgttt taatgaagtt atggctatag atggattaat tatgattact
    49621 caatatgatg tattttggag agaggataag tttgatgggt ggcattttta tgatttgtca
    49681 cagagtatgg agtttagaca aaataaatac aaagttattg taccaaaaca aaataagcct
    49741 tggtgtatgc atgattctgg agtagtaaat ataaataatg gatatgatga atataggata
    49801 aaatttgtaa aagagtacat aaatcttgat ttatatagag aaaattttta tgaatttgat
    49861 aagaagaaag caagtaccat acttaagagt aataagcatg taatggattg tatgaaagag
    49921 gagcttacag aacaattaag attaaagaat tacaaggatg ttttaggtat tgtttctaaa
    49981 attgctcatt tttctgtttt taatcatact ggtttgtatt cttgtgaaga atgtgagaga
    50041 gcattgctag aatgtgcaaa taatttacca gaaatagaaa atacgaaatt atttacaaaa
    50101 aaagatttaa aaagaagaaa agtattacat gttttaagtg aaggatattc aacaggaggt
    50161 catacaagac tagttaaaaa ttggattgaa attgacaaag actctgttca ttcagttgta
    50221 actacatggc aatcagatac actgccagac tggttattaa aagcaataaa tgatagtggt
    50281 ggcgaagtta tatctttgga tttaatttca gatgattatt taaaaagagc tgtagctttg
    50341 aggaaaatag cttatgactg ggctgatata gttattttat atgttcatat gtgggataca
    50401 atacctgttg ttgcttttgg agttgatggg aaaataccta ttttacatgt taatcactat
    50461 gatagtactt tttggttagg gacaagtatt gcagatattg tcattgattt tagcgaaact
    50521 agtcaattaa ttacattaga taaaagaggc atagataaat ctgaaatatt accaatgcca
    50581 ttaaaagaaa aagaagtatt ttcaaaatct gaagttagaa aacgatataa tttagaggat
    50641 gatgtgacaa taatattgac tattgctagt gaaagaaaat acaatagtgt aaatgatatt
    50701 aattacttta aaattgctaa aacattgatt gaaaatacag ataatacaat tattattgtt
    50761 gtaggagttg atacagagaa tctctattgg aaaactttaa gtaatgttac agataataga
    50821 gttatatgtt ttggaacaac agcaaatata gatgattttt ataagatttc ggatatatac
    50881 ctagagtctt tcatggtagg aagtcatact tcaaaattag atgcaatttt atatgattta
    50941 attcctgtta agtttaaaaa tgaagtttca ccaattttta caaatatgtg gaattttata
    51001 gataagtttg attataagaa tataaaagag gttatagaca tgataagaag gtacaatact
    51061 agtgaatttg acagggataa gataaaagca aaacaatcgg aaataaaaca ttttgttata
    51121 gataaacatt gtattgaaat aaaaaactat atagacaaaa tatataatga agttaatcat
    51181 cataaagtta agtatgattt atataaaaat gatgaaatcg aggactatca gctttttgta
    51241 gcattatatg gctatatggt aaaaaataaa aacatgtcat aggtggtaaa atgaacaata
    51301 ttcatatcaa taaatttgaa aaaagctgtg aaaaaaactg ggattatttt gtagaaaata
    51361 aatctataaa tggtacattt ctgcaaacta gaaatttcct taattatcat gaggagggaa
    51421 aattcactga ccactcatta ataatatgta aaggtgaaga aatactagca gtcgtacctg
    51481 catgtgaaac ttatgaagat ggtgaaagaa tatttttttc tcatttaggg agtacttttg
    51541 gtggcattat aataagaagt ggttttaatg atattaggca tgtaaatgcc attacaaata
    51601 agttagaaat atatttacag gaacaaaatt tcgataaagt atatttaaaa aatacatcaa
    51661 gaatattttg taaagaggat acttcattac tagaatattt tttatttaag aataattaca
    51721 tgttttatga tgaattaagt atgtttttag aattaagtaa gtataaagaa gatatattag
    51781 ccaattttaa atacagtaaa agaagagatt ttaaatattc tttgaagaat aatcttacct
    51841 ttaaaagact gtatagtgat gaagatatag tttgtttttt taatttactt tctaattgtt
    51901 tagatagtaa aggagctaaa gtaatacatt cagtagaaga acttttggag tttaaaaata
    51961 atagattaaa agatattgta gaattttatg cagtatatat tgatgacatt atgatttgtg
    52021 ggagcatggt atttaacttt caagaaagag tttatcatac tcaatatcta gcatcaaatt
    52081 cgacatataa taaatattat ccaatgatat ttttatacta taatctaata aaagatgctt
    52141 tagagagaaa ttttaagtat ctttcttttg gaattagcac tctaaataga ggcaaatact
    52201 tagatgaggg tttagctaca tttaaagaag gttttggttc aagtgcaatt tgtaacagaa
    52261 catactataa aaatataaat aagtgagaat catgttttat agagttttta gagtatagta
    52321 aatatctagt actataatat tacataaaaa taattagttt ataaagaagg tttgtatatg
    52381 aaaagattaa tgattttagg ctcaattaag tattttgaga atattgttat gtcagctaaa
    52441 agagagggaa tatacacaat tgtttgtgat aatagaattg atactcctgc gaaaaagatt
    52501 tgtgatgaag caatagatgt tgatgtattt gattttgata aaataaagaa tatagctata
    52561 gataaaaaga tagatggaat tttaactgga tttacagatt ctttaatgaa gccatatgtt
    52621 tatattgcaa atgaactaaa tttgccatgt gtgatttctt gcaatcaact tgaatctgta
    52681 actaataagg ctgttatgaa aaattatttt aaaaataatg gaatacctac aactgattat
    52741 tgtattattg aaagtttgaa agatttagaa aaaatacaag gattaaattt tccacttgta
    52801 ataaaacctg ttgatggtta tggttcaaga ggtgtatatt ttgtatcaaa catagaagaa
    52861 ttaatagaaa aatttgaata ttctaaggaa gcctcgcaag atggacaagt aataattgag
    52921 gaattttatg aaagtgagga aatacaagga ctagcttggg ttcataatgg agagtcacat
    52981 gtattttata ttggagatag agagcttgta aatatacata caggaagagc tggaaaacca
    53041 gatagattaa tttatccatc aaagtattgt tttcaatatg aagaagaaat aaaatccata
    53101 tatcaaaata taacgcaggc ttttggcata aaaaatggac ctctttatgt acaaatgtta
    53161 gtgggagcat atggaataaa ggtatctgaa gtaatgccaa gattacctgg aggttgtgac
    53221 tatatggcta tttctcaaat aacagattta gacataggaa gtttatttgc aaactttagt
    53281 gtgaataatg aagtaaattt tgatgaaata aagaaatata atatgcatct atcaaaatgt
    53341 gtatatgcat taccaatata cataagacct ggcacaataa aaaagataaa taatatagat
    53401 aaaatagaaa acttagatta tgtcactcaa tttctattac tagtaaaaga aggagataca
    53461 ataggattat atgaagatga gagacaggat tgtggaagag tttatggagt agcaaataat
    53521 gtatttgatg caaatataaa gaagaaatgt attcatgaaa tgatagaaat acttgatgaa
    53581 aataatgaaa atatgataga aaatttttaa ataagggagt atgatagata tgaagctaat
    53641 aactcatgaa caaattatgt cattaaacat ttctcagaaa caaggatacg agtggataaa
    53701 agaatccttt ttaacaaaaa aagattgtca attaccacca aaaataagca tggtagaaga
    53761 agggcatgta ttttacaatg taatgccgtc cctaaatcat aatcataaga ttggtggaat
    53821 aaaaatggtt acaagattgc cagggagaaa tccaagttta aattcagaga tatttctata
    53881 taatatggaa gatgctaaat taaaggctat tttagatggc aattatatta cagcttttag
    53941 gactgctgct gttgctgcct tggctatcga tacatttgct aaaaaagatt ttaatactat
    54001 tgctattatg ggtttaggtg taactgcttc tgctataatg aatatgcttt catatactct
    54061 taaagataaa aatataaata taaagttact taaatataaa gaccaagcag agtcgtttgt
    54121 aaaaaagtat gaaaaaaatg aacaatttag ttttgaaata tgtgacacac atgaagaact
    54181 tattgtagat tcagatgtag ttatttctac tgtgacatat acagatgaat atttatcaga
    54241 atttaaatgg tttaaaaaag gtgctttatt attacctgta catgttatgg gatttggaaa
    54301 tgttgattat ctatttgata aagtatattt ggatgattat aatcatttga aacatctaga
    54361 aaatatagat agatataaat attcttgtga attttatgat gttttaagta aacaagctaa
    54421 aggaagagaa aatgatgatg agagaataat atcttacaat ataggtttgt caatacatga
    54481 tatattattt gcaaataaaa tttacgaatt gtgtgaaaca ctaagctgtg aagaaataga
    54541 attaaaagaa ccaaaagaaa aatattggat atagtttatt tcattcatat ttacaatagt
    54601 ttattgtaaa tatgaatatg aagtaatata ttgttagaaa attagcatga ataggataga
    54661 taaatttatg gataaatata atttaattag gttcgtatct attggaaacg aatatatagg
    54721 aaatttagtt gcattagaat caaataaagc aatacctttt gatataaaga gagtttatta
    54781 catatatgat gtaccaaaca atgtaaagag aggatttcat gcacacaaaa acttggaaca
    54841 agtactagtt tgcctaaatg gaagtgtgaa gataaaatgt tatgatggtg taaaagagac
    54901 tatatttaat ttacataaaa atgatgttgg attatatata ggaacgggag tgtggcatga
    54961 gatgtttgat tttgatgaaa aaactgtttt aatttctata gcatctgaac attataatga
    55021 agaagattat attagagact ataaagaatt tttaaagtat ttaaataatg tgtagttatt
    55081 atacaattag tgatgtattt tcttaattaa ataaatttaa gatagccaca tagagaatag
    55141 atagattagg atgtgaattt attgttggtt aaatttaata atttattaaa acagttccaa
    55201 actcataaag aagaatatga acagaagatt aaggatgtaa tggaaagtgg atattatatc
    55261 cttggaaatg aagtaaagca ttttgaagaa gaatttgcta actatgtagg tagcaaatat
    55321 tgtgttggtt tagccagtgg tttagatgca ctgataattg cttttagagc attaggaata
    55381 agcaaaggtg atgaagtaat cgtgcaatca aatacatata ttgctagtgt tatgggaatc
    55441 agtataaatg gagcaacacc agtatttgta gaaccaaatg aatattataa tatagattca
    55501 tctaagatag aagaaaagat aaatagcaaa acaaaagcta tattagtagt gcatttatat
    55561 ggtcaagcaa gtaatatgaa agatatacaa gaattatgtg ataagtataa cttgtattta
    55621 attgaagatt gtgctcaatc tcatggagct aaatatgatg gaaaaatgac aggaacattt
    55681 ggtgatatag gttgttttag tttttatcca agtaaaaatt tgggtgcatt tggagatgca
    55741 ggagctatag taactagtaa tgaggaaata gctgataaag tgaaaattct tagaaactat
    55801 ggctcagaaa agcgatatta taataaattt gtcggatata attcaagatt ggacgaaatt
    55861 caggcaggtt tattaagagt aaaacttaaa tatctaaatg aaattgaaat tgaaaaatca
    55921 aaaatcgtag atagatatct taatgaaatt aataatccca aagtcatact tccaaagata
    55981 gaaaataatt gtactcatgt atggcattta tttgttttac aagttgaaaa acgagataca
    56041 tttatggaat acttaaagaa aagtggtata gagtctataa tacattatcc gataccacca
    56101 catctatctg aagcatatgc ttatttggga tataaaaagg ggagttttaa tatagctgag
    56161 aactattcag ataaagttgt tagtatacct ttatttattg gtatggaaga tgaagaagtt
    56221 agtt
//
LOCUS       DAGQVA010000018        51959 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.018, whole genome shotgun sequence.
ACCESSION   DAGQVA010000018 DAGQVA010000000
VERSION     DAGQVA010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51959
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.018"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(425..565)
                     /locus_tag="MIV85_001255"
     CDS             complement(425..565)
                     /locus_tag="MIV85_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960620.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(823..1983)
                     /locus_tag="MIV85_001256"
     CDS             complement(823..1983)
                     /locus_tag="MIV85_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBY2960621.1"
                     /translation="MKLNKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGSVSAVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSISDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(2154..2357)
                     /locus_tag="MIV85_001257"
     CDS             complement(2154..2357)
                     /locus_tag="MIV85_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBY2960622.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(2444..3478)
                     /locus_tag="MIV85_001258"
     CDS             complement(2444..3478)
                     /locus_tag="MIV85_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBY2960623.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTATSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKEAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSKFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(4000..5361)
                     /gene="rlmD"
                     /locus_tag="MIV85_001259"
     CDS             complement(4000..5361)
                     /gene="rlmD"
                     /locus_tag="MIV85_001259"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBY2960624.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIIVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(5388..6110)
                     /locus_tag="MIV85_001260"
     CDS             complement(5388..6110)
                     /locus_tag="MIV85_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBY2960625.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(6110..6439)
                     /locus_tag="MIV85_001261"
     CDS             complement(6110..6439)
                     /locus_tag="MIV85_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBY2960626.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            6769..7695
                     /gene="fba"
                     /locus_tag="MIV85_001262"
     CDS             6769..7695
                     /gene="fba"
                     /locus_tag="MIV85_001262"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBY2960627.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(7830..9461)
                     /locus_tag="MIV85_001263"
     CDS             complement(7830..9461)
                     /locus_tag="MIV85_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2960628.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(9944..10981)
                     /locus_tag="MIV85_001264"
     CDS             complement(9944..10981)
                     /locus_tag="MIV85_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBY2960629.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(11000..11785)
                     /locus_tag="MIV85_001265"
     CDS             complement(11000..11785)
                     /locus_tag="MIV85_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBY2960630.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(11818..12951)
                     /locus_tag="MIV85_001266"
     CDS             complement(11818..12951)
                     /locus_tag="MIV85_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBY2960631.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(12999..14126)
                     /gene="hadC"
                     /locus_tag="MIV85_001267"
     CDS             complement(12999..14126)
                     /gene="hadC"
                     /locus_tag="MIV85_001267"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBY2960632.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(14126..15352)
                     /gene="hadB"
                     /locus_tag="MIV85_001268"
     CDS             complement(14126..15352)
                     /gene="hadB"
                     /locus_tag="MIV85_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBY2960633.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(15367..16167)
                     /gene="hadI"
                     /locus_tag="MIV85_001269"
     CDS             complement(15367..16167)
                     /gene="hadI"
                     /locus_tag="MIV85_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBY2960634.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(16206..17405)
                     /gene="hadA"
                     /locus_tag="MIV85_001270"
     CDS             complement(16206..17405)
                     /gene="hadA"
                     /locus_tag="MIV85_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBY2960635.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            18082..19080
                     /locus_tag="MIV85_001271"
     CDS             18082..19080
                     /locus_tag="MIV85_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBY2960636.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            19442..19969
                     /locus_tag="MIV85_001272"
     CDS             19442..19969
                     /locus_tag="MIV85_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBY2960637.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            19996..20592
                     /locus_tag="MIV85_001273"
     CDS             19996..20592
                     /locus_tag="MIV85_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBY2960638.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(20657..22240)
                     /gene="asnB"
                     /locus_tag="MIV85_001274"
     CDS             complement(20657..22240)
                     /gene="asnB"
                     /locus_tag="MIV85_001274"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBY2960639.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(22806..23642)
                     /locus_tag="MIV85_001275"
     CDS             complement(22806..23642)
                     /locus_tag="MIV85_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2960640.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(23666..25132)
                     /locus_tag="MIV85_001276"
     CDS             complement(23666..25132)
                     /locus_tag="MIV85_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBY2960641.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQRKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIESNSIDFK"
     gene            complement(25135..26997)
                     /locus_tag="MIV85_001277"
     CDS             complement(25135..26997)
                     /locus_tag="MIV85_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2960642.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(27244..28107)
                     /locus_tag="MIV85_001278"
     CDS             complement(27244..28107)
                     /locus_tag="MIV85_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBY2960643.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(28162..29094)
                     /locus_tag="MIV85_001279"
     CDS             complement(28162..29094)
                     /locus_tag="MIV85_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBY2960644.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(29180..29731)
                     /locus_tag="MIV85_001280"
     CDS             complement(29180..29731)
                     /locus_tag="MIV85_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2960645.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(29960..30451)
                     /locus_tag="MIV85_001281"
     CDS             complement(29960..30451)
                     /locus_tag="MIV85_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960646.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(30479..31039)
                     /locus_tag="MIV85_001282"
     CDS             complement(30479..31039)
                     /locus_tag="MIV85_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBY2960647.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(31191..32348)
                     /locus_tag="MIV85_001283"
     CDS             complement(31191..32348)
                     /locus_tag="MIV85_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBY2960648.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(32385..33326)
                     /locus_tag="MIV85_001284"
     CDS             complement(32385..33326)
                     /locus_tag="MIV85_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960649.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLNQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(33413..34105)
                     /locus_tag="MIV85_001285"
     CDS             complement(33413..34105)
                     /locus_tag="MIV85_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBY2960650.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(34214..35026)
                     /locus_tag="MIV85_001286"
     CDS             complement(34214..35026)
                     /locus_tag="MIV85_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBY2960651.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(35077..35988)
                     /locus_tag="MIV85_001287"
     CDS             complement(35077..35988)
                     /locus_tag="MIV85_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2960652.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKFIEAGKFELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(36047..36778)
                     /locus_tag="MIV85_001288"
     CDS             complement(36047..36778)
                     /locus_tag="MIV85_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBY2960653.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            36867..37118
                     /locus_tag="MIV85_001289"
     CDS             36867..37118
                     /locus_tag="MIV85_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960654.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            37352..37771
                     /locus_tag="MIV85_001290"
     CDS             37352..37771
                     /locus_tag="MIV85_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960655.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            37796..42853
                     /locus_tag="MIV85_001291"
     CDS             37796..42853
                     /locus_tag="MIV85_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBY2960656.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(43039..43776)
                     /locus_tag="MIV85_001292"
     CDS             complement(43039..43776)
                     /locus_tag="MIV85_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960657.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(43795..44730)
                     /locus_tag="MIV85_001293"
     CDS             complement(43795..44730)
                     /locus_tag="MIV85_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBY2960658.1"
                     /translation="MANNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRVHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            44938..47514
                     /locus_tag="MIV85_001294"
     CDS             44938..47514
                     /locus_tag="MIV85_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBY2960659.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVILANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            47526..48197
                     /locus_tag="MIV85_001295"
     CDS             47526..48197
                     /locus_tag="MIV85_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960660.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            48224..48565
                     /locus_tag="MIV85_001296"
     CDS             48224..48565
                     /locus_tag="MIV85_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960661.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(48925..51567)
                     /gene="adhE"
                     /locus_tag="MIV85_001297"
                     /gene_synonym="adhC"
     CDS             complement(48925..51567)
                     /gene="adhE"
                     /locus_tag="MIV85_001297"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBY2960662.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        17302 a         8768 c         6201 g        19688 t
ORIGIN      
        1 tttttataat aaattgtata cattataaat tatattaaat ttttaattta agtaatagta
       61 tatgtaatct ttagtcatct tcttaccagt tttttatcca cttttctaat gaagttattt
      121 tttcatatgt taattcctct tgaaataatg atactaaaag actttttata aaattataac
      181 ttaaaagttt atgtattttt ttgatatgaa tttatagtac ttatcttctt taattgagat
      241 tgtgtatatt taactaaaca ttacaacaat aattctatga aatcaaatca attatttaca
      301 tattttttta gaacaataat aagtatatat tcacaaaatt ttgtgttaat atttttaatt
      361 tgtgatataa taaaagcaag gaaacatatt ttacttaact ttgagtgatg tttccttcaa
      421 caaattattt tgaagattta cttttctgga actttatatt aagttcccag ccactcttag
      481 ttggtcgctc agagtggctc tttaatttat cgtaaatgta actggctata acaccagtta
      541 taatactcat cattagattt tccatagttt tcacctcctc tcataagaaa gtgaagaaac
      601 ttccatggaa acaccactca tagctttttc aaatatttat tccttgccat attaattata
      661 tcataaatat tggaaacata aaattttaat acttatcgtc tttattatta ttttttataa
      721 ttaataattt tttttaataa tacataatat aaatttatat ttcttcaata aaaaagacaa
      781 tcttaattaa ttgtcttttt taatatatat ttggctaata cattatttta cacaaacatt
      841 acaagggtct attttacctt gtgacttagc ttgttttaat gttactttat ttattgtttt
      901 acttcttttt agtgtagaac aattttttgt tagatgatat gattttccat taggagttac
      961 atatactgta cttttatcag ttaatccagg attattagag ctaggctcat tacttggttt
     1021 gttcgtatta tttgaattag tatcttttac aatgcctgta tttgaatccc caacattatt
     1081 agttatattt aaacattgtt ttataacaac atcatcaata tttccaatag cagttatttt
     1141 acttgcattt tttaatatac tcttattact tccatttcca actaacacta taggtgtttt
     1201 ttgtgcaatt gtagaaccaa ctaaagaata aactaaatca gtcccacttg ctatgtaaaa
     1261 ttcttttgag ccattataaa atttatttat tatttgttta tttgtatcgt atctatctac
     1321 tccacctatt cttgttgctt tagtttcatt tattaactta tcactaatac tgacttttcc
     1381 accaattgca taagtttcta atccatctgt agcaaaactt gtagtgtttc catcagttaa
     1441 tactattgga gatttatctc taactgctat agaagcaaca ctcatagcat ctggttcacc
     1501 tttaaaagca ttagttaata ttactttttt aacagcactt acacttccta tttcttttgc
     1561 aactttatga cttgtatcta ttctatcagt tccacttatt ctatttatgc ttattttttt
     1621 atcacttaat attttctgaa ctgatgctcc tatcgaattt tttcctccga ttagatatac
     1681 ttcttttacc ttttctaatc tttttaatgt ttctgaaggg attgtatctt tcttagttaa
     1741 caatattggg gcatttttag ctcctgacaa tccacttgct gacaatccat cagataatcc
     1801 attttcagaa ttaataagta ttgcaatatc ataattttgt ttatctgcta ttaaacctgc
     1861 tgtttcatac ttatttgtac cttttattga attaatagaa ctaagagcgt ttgatgttgg
     1921 acaactagca atcaataatg aaacagacat ccctattgcc aatagtgttt tgtttaattt
     1981 cataatgaaa tcctcctata aattttataa tattacttaa atattataat tctacataaa
     2041 agaatatttt cctttatgaa attagtttat atttcaaaat tttgtcactt tttaaatcta
     2101 tatactaaaa aatagactat ttgtaacagt ctatttctta gtatatcaaa tatttattta
     2161 ggtttacgtt tctttgtact agtttttgta tatgatattc cagttccagg tatactcaat
     2221 gtagctgatt ttcttccttt tgaattaact gacactctag cacctttaac accagcactt
     2281 atacctacac tcttcttacc taaatttaat ttgagtcctc ctcctagatt tatgcttttc
     2341 ctaaagttaa atcccataga tataaccttc ccttctatat tttaaatatt tatacttaaa
     2401 attatatttg ttatacactt gccatcattg gtatatctag catctatatc tttttacgtt
     2461 ttttcttctt atatactact ccagcaacta cagctgctgt tccagctcca accccataag
     2521 tagcatttct acttttctct tcttctcttt tttctaaacc ttcatcatat acacctttta
     2581 acttagtttc aatagacttc atttcatctg gtatactaaa atcttcttca ttgtaacctt
     2641 gattatatac actttctttt gctttaggta acttaacctt accattatca tatccttctt
     2701 taaaccaatt agcatattta acattaccta tagttgatgt gtcaaatctt tctcctttga
     2761 tagcactctc aaatccttga gtagtgtaat cattttttaa ttgttcttgt atttcgtcat
     2821 aagcattatt ataagcatct ataaatttag aatctatgtt ttcttcaaat gtcatttttt
     2881 ctttatcttt attgctatcc tctatccctt tagctttata ttcttctatc tttttagtct
     2941 tatattcatt gtatccagtt gaatatccgg tatcataagc attttttaaa acttcttttt
     3001 catatgtatt attagattta gcacctgtaa gccctagatt atatccagtc tctttagcct
     3061 ccttttcttc ctcttctaat ttagccttac ctttttcata tccttctgag tactttgatt
     3121 catatgtatc actataatct ccactataat ttgatgaact ataatttcct ttatacccat
     3181 cttcataccc ttgattatat cctttttctc caacagacct cttttgcttt tcttcattat
     3241 taaccgaagt tgctgttcca gaactgcttc ctcctccagt ataaggacaa ccaccattat
     3301 tatgtaaatg agctggataa ccaccacaat gatagtgata acttcctaat ccagatttat
     3361 ttttattatc acgatgacct cctgatgaat cagttcttcc tgaatgagca tacgaaaagc
     3421 tccctacact aatcatagtt atactcattg caacagctat taactttttc ttaaacataa
     3481 tctatttccc cctaaaatat tctatgattt tattatatca gtcaatatat tatgtttaaa
     3541 ccgttaaaat tcgacaatgt aaatatttga tgaattgtat ttgtaaataa atcttttagc
     3601 atatcttgaa tatctgtagt tgttttgaca tcatattctt caataagttt tttaatattt
     3661 cgtttttgtt aaacataaaa agcgtgcact tttctttgta tagtgatatt tgatatttta
     3721 attatcacta ctttagaaga atacacactt tattttaaaa accctgatac tatgttatta
     3781 gaaaatggta ctaatataaa agatatccag catatactcg gacatgctaa aacttcaaca
     3841 actatggata catatttaca tgtaactaac aacatgagaa accagacggt aaatattttt
     3901 gaaatcattg tagaataaat ttgccaccca aaaataatta tggtggcaaa taggtggcaa
     3961 atctactttt aagacacact ataaaagtct gaaaccctgt tattctctaa taagtttaac
     4021 tacagtctca caatgtggcg tatttgggaa catatccata cacttaacca tcttaatctc
     4081 ataaccatac cccttaaaat caaccaaatc aacaaccaaa gacttaggat tacaagaaat
     4141 ataaacaatc tccttagcac caaatccaca aatatcccta atagcatcct tatgaatgcc
     4201 tggtctagga gggtcaacaa taatcaaatc aggcttgtcc tttaaatcct taacaacctt
     4261 agccacatcc ccagcaataa actcacaatt agtaagtcca ttcaacttag cattctcatt
     4321 agcagcaaca acagcttcct caactatctc aataccatac actttcttag cagcaccagc
     4381 cataacctgt ccaatagacc cagtaccact atacaagtca aatacaactt tatcattgta
     4441 atctccaata aaatccctag caatactata aagaacctca gctcccttag tattggtttg
     4501 gaaaaacgaa aatggtgaaa tcttaaactt aagacctaaa atttcttctt gtatataatc
     4561 tcttccatac aatactctta actcatcaca ttggactgca tctgctaaac catcattaat
     4621 agtatgaagt acacctacta actcagcttt taaatcaatc cctaaaagca tatctttaaa
     4681 ctcatacata tcaaaatctt cttgagaaga agttactata ttaactataa tctcattagt
     4741 gtgaatccct tttctaacta caagatgtct caaatatcct ttgtgattca ttgttctata
     4801 ataaggaagc tttttttcat tgaaaaactc tacactagaa actaatatct ttgagaagtc
     4861 ttcatcaacc aacatacact cctcaacagt ttgtatatct atatgctttc cttttttatg
     4921 aagacctaat gtcaaaggtc cattttttac ttcatctcca aaagtatatt ccatcttatt
     4981 tctataatat ttgttttctg gacttccttc tatccctaaa aactgaaatc caaataaatc
     5041 ttgctttaaa aataaatcca taacttgttt ttcttttatt tctaattgtt tttcatatgg
     5101 cacagacaat agtgtacatc ctccacactc tctaaagtgc ttgcaagttt cttcagtttc
     5161 aagtggtgag ttctctaata attctatcat cttaacttca gctttcttac ttctaacttt
     5221 tttaactcca gctctcacct tttgaccact tattccaccc ttcatatgga taactctatc
     5281 tccaacttgg cttaaagatg taccaccaaa ttccatttta tctacttcaa attctataac
     5341 atcttttttc ttcacagaca ttcctccaat ttactatagt atctttatta tctttcttca
     5401 atcaatttta cttcttcatc tgttaactct ctatactcac ctaactctaa actttcatcc
     5461 aattttaaat tgcccataga caatcttttt aagtatacta cttttttgcc tacgctttca
     5521 aacattcttt ttacttggtg aaacttacct tcatgtattg taagctctat ttctgattca
     5581 tcatcacttt ttaatatatt taactgtgat ggcatagttt tatatccgtc atcaagcact
     5641 acaccttcta aaaaagcttc tacatcttct tcagtaacta ctccatcaat ttttgcataa
     5701 taagtcttag gcacatgctt cttaggagat aaaactctat gagaaagctt tccatcatta
     5761 gttaaaacta ataatccctc tgtgtcttta tctaaccttc caacaggaaa tggttcaaaa
     5821 gctaagtatg ataaatcaat taaatctaat actgttgggt catatttatc tgtagttgct
     5881 gatatatatc catcaggttt attcatcatc aaatatatat attctctata tataacttct
     5941 tctccattaa ataatatctc atcattttca gtgtctactt gagttcctgg atttgaaact
     6001 tcacttccat ttactactac agacccttgt ttacaatact tctttatttc acttctgctt
     6061 ccataaccta aatttgaaag aattttatct atacgttgct ttttagccat taaaaatgct
     6121 ctccattctc ataatatttt tctttttcaa atactgtaaa tgctaaatcc atactttcta
     6181 catctaaatt atttcttata ctatcagtta ttattcttgc tactatatct tgtacttctt
     6241 gtcctctatc aaaccaagct acttcaacaa aaggatatac atctgctatt ttaccatctc
     6301 ttattgcaac tgactttata cattctattt caaagtagtc tcttggacat tttacagctt
     6361 caactaaatc atttatcatt ttttcactta ttttacatat atcattttca ttaattcctc
     6421 ttatttttat ctgtggcata gtttatctcc tttattttaa atttttagtg aattatcatc
     6481 cacttaattc ccttcgataa cgtttgaagt ggtaacttct tggtcaagac aactattgtt
     6541 atcagtatct ccaaactaat aaggtagttc ctacccttat agttagcatt atatagctaa
     6601 ttttcctaaa ttgtttatat tctttattat tttatttaat cctattgtct tctatttaac
     6661 attatacttg taatttatag ttattacaat ttactatata ctttttttga tttaacgtta
     6721 taatataagt gatgggtaaa ttttaaaagt taataggagg agtttaaaat ggcattaatt
     6781 actacaaaag aaatgtttaa aaaagcttac gaaggtggat ttgctatagg tgcatttaac
     6841 ataagtgact tagaacaatt acaaggtgtt ttaaaagctg ctaaagctaa aaattcttat
     6901 gttatgatac aagcttctat gtcagctgtt aaatatgctg gacctcatac attagttgaa
     6961 atggttaagg ctgcttctga tgaaataggt gtagatgtag ctcttcactt agaccatggt
     7021 ccaaatatgg atgctattaa aacttgtatt gatgctggtt tctcttcagt tatgatagat
     7081 ggttctcatt ttgactttga agaaaatgtt agaataacta aagaagctgt tgaatatgca
     7141 cactctaaag gtgttgttgt tgaagcagaa cttggtgttc tagctggaac agaagatgat
     7201 gttacttctg atgttcacaa gtatactcaa ccagctgagg cagttgagtt cgttgaaaga
     7261 acaggtgttg attcattagc aatagctatt ggaacttctc atggtgcttt caaattcaaa
     7321 ggagaagcta aattaagatt cgatatacta gaagaaatcc aaagcaaatt accaggtttc
     7381 ccaatagttc ttcatggtgc atctgctgtt gaccaaaacg ctgttgctac atgtaatgaa
     7441 tttggtggaa atatagctgg tgctaaaggt gtacctgtag atatgttaag aaaagcatct
     7501 tctatggctg tttgtaaaat aaacatggat actgacttaa gactagctat gactgctgct
     7561 atcagaaaat tcttagctga aaatccaaaa gaatttgacc caagaaaata cattggtgct
     7621 ggtagagatg ctatacaagc tgtagttgaa agcaagatag atgatgtttt aggttctgct
     7681 aactctataa actaatataa cttttaaata tttataaaag aaaagagatg acttaaagta
     7741 attaaattta tttttaagcc atctctttta agttgtataa attatgtatc ttataatatt
     7801 ttaattatat tgtcttttta aactgacagc taaacgtgaa tatgtccact ctttatcttt
     7861 ctatggatgg tagaaggata tatacctata acttcagcag cctttgttat tgaaccatac
     7921 ttatttatag ccttacttat cattatttgg tccactattt tatatgcatc attaagattc
     7981 ataattccat ttaccactat tggtgataaa tcatctgttt cattatcaat catatctaaa
     8041 tttatcagca tgttaaattc atcttctcca attacatttt tagctgataa tactacaaat
     8101 ctttcaatga tgttttttaa ttctcttatg tttcctggcc aagaatattc ttctaataac
     8161 tcaataactt taggcgaaac ttctacttct ctattgtact tttcattgta aagttttaag
     8221 aaataattta ctaatggtac tatatcctct tttctttctc taagaggagg tatttttact
     8281 ggaataacac ttaatctata gtacaaatct tgtctaaatt taaggttatt tctaaggtct
     8341 tcatgagaaa tattagtagc acttatatat ctaacatcta tttttatagg cttactacca
     8401 cctattctag taatagtatt ttcttgtata accctaagta attttttttg catctgcatt
     8461 ggtaactcac ctatctcatc caagaaaata gttccaccat tcgcctcttc aaaaagtccc
     8521 tttttacctt ttttcttagc tccagtaaaa gaaccttctt catatccaaa aaactctgac
     8581 tctaataatt catttggtat agctccacag tttatagcta taaagggttt gtctctcctt
     8641 gaactatact tatatattgt tcttgctatt atttcttttc ctacacctga ttctccattt
     8701 ataaatatag aagaatctga ggctgcagct ctcttaacaa ctttttttat attgtccata
     8761 atcttacttt gacttatata ctctgtgtct tctgatatat cactatattt tatctgagat
     8821 tcaagcttaa taacccttga aatatctctc cctgttagta ctcctcctgt aagctttccc
     8881 ttagaatccc atcttggaac tgccgtatat gcaataagct tcccatctgg gtaaacgata
     8941 tttctataaa tctttttctt cactttaagc atgtttaata ttattggttc ttcaactaat
     9001 ccttgtctca caaggtctgt tatatttcta ccaagtacct cagttctttt aaaaggtaat
     9061 atctcatcac tgacagtgtt catcttttca attaccccat ctttgttaaa cacaacaaca
     9121 acttcatcta tatgctctat tatatcttca attactttat cagatattag agacttctca
     9181 aataaataaa ctatattatt ttcattatta ttatctttca tattgtatat atgtgcagtc
     9241 atccttaact ctctgaaagc tattttcttt ttactatctg tcagtatttc tgttttgtca
     9301 aaatttgaat ctaattcatt tatatttcta ggctttttta tatctagaaa actaaaaata
     9361 ctatctatta gatgattaca gtatattatt tcgcctgatt ctttacataa aatggctgga
     9421 ttttctacat gttctataag ccctattaaa ttattatcca ttaatattcg cacctttcat
     9481 taagtaattt attgaactac atacaaaatt tattgtttgc ttacaataaa taccatcagc
     9541 acatataatc aactccttat aatattcgtc ttttcaagta gtttatttca ttaaaacgta
     9601 actaagatat aattttaatg attatagttt gttaaaaatt tcattttgct tttaattgta
     9661 ttttatcaca tatttagtaa ttatttgtct atttaataca atttaattaa atttaagatt
     9721 tatttaaaaa aacaaagata atccttacag aatataactc acaatttgta agcaatatac
     9781 atataaggat tatccagatt atcttgtatt ataaaatttt attcaaacag actttttaat
     9841 aactgacaaa tacacactag caataactta tcaaagggtt aataattatg ttactaacta
     9901 ataagactta ttcaatcagt aatatttata tagtttgtat ctattaagct tttatagctt
     9961 ctaataaatc atcaacgcta tctaattttt ctataagcat tggaactatt tcatgtaagt
    10021 ctccaactac tccatagtca gcgatttcta aaattggagc tgctgggttt ttgtttatag
    10081 caattatgaa atctgatgat tgcatacctg ctaaatgttg tattgctcct gatataccac
    10141 aagctatata taggtttggt ttaacagtag ttcctgtttg acctacttgg tgagaatggt
    10201 ctatccatcc agcatcaaca gccgcacgag aagaaccaac tactccacct aatttgtcag
    10261 ctaatttctt aagcatttca aatccttctg gtccacctaa tcctaaacca cctgatacta
    10321 taacatttgc atctgtaaga gatactaaat ctttcttagt tttaactgtt tctaaaacag
    10381 tagttcttat atcatcttga gttattttgt agtctaatgc tataacttca ccagttcttg
    10441 tttcgtcttt ttcagcttta tccataacac caggtctaac tgtagacatt tgaggtctat
    10501 ggtttggaca aatgattgta gccattatgt ttccaccaaa tgctggacga gtttgtttta
    10561 ttttcttatc ttctgggtct atttctaact tagtacagtc agctgttaat ccagttccaa
    10621 ctcttgaagc tattctaggt gctaagtctc tacctatatg agttgctccg aaaagcatta
    10681 tttctggttt tatttcatct attgcatctt ttattacttt tgtatatgca tcagttgtat
    10741 atttttctaa aagagcatca tctgcaacat aaactttgtc agctccaaaa gtgattaatt
    10801 ctttagctaa tccatcaaca tcttttccta ataatattgc acaaagttct gcatctactt
    10861 ctttagctaa ttttcttcct tctcctaata attctataac tactggagct atttttcctt
    10921 ctctttgttc tgcaaatatc catacgtttt tataagaact taaatctttt atatcattca
    10981 tagtttgtac tcctccaact tatataatgt gcttttgttt tagaccgatt attattttac
    11041 tagctatttc atcagcttta ccttctaaga tttctccttt tcctcttggt tcaggagtaa
    11101 atgatctaaa tactttagtt ggtgatgctt ttaaaccaac ttcttcttta tttacatcta
    11161 aatcatcaat tgtccaaact tttacatcat gtttatatgc ttttactatt ttatcaacag
    11221 acatgtatct aggtgtattt aactctttta ctgctgttaa aagtacaggt gtacttactt
    11281 ttattaattc gtatccatct tctaattgtc tttgaactat tatatctttt ccttctattt
    11341 tgaaatcttg tacatatgta acttgaggaa tgtctaattt ctctgcaatt tgtggtccaa
    11401 cttgtgcagt atctccatct attgcttgtc ttcctgcaaa tattatgtca tagtcaccta
    11461 ctttagatat tcccgctgca atagtatttg atgtagccca agtatcagct cctccaaatg
    11521 ctctatcact taataatatt gcatcatcag cacccatagc taaacactct cttagcataa
    11581 agtctgcttg aggaggtccc attgttataa ctgttatagt tacatcatca tgctcatctt
    11641 taatttttaa agcttcctct aatgcatttg catcatctgg gtttaatata cttggaactc
    11701 catctcttat aagagtacct gtttctttat ttattcttac ttcgttagta tctggaactt
    11761 gttttacgca aactaatatt ttcaaagtct atacctccaa tttcattaga ttatttatta
    11821 ttttaatacg tttgatgaaa ttaccatttt ttgaacttct gatgttcctt cgtatattga
    11881 tacgattcta gcatctctgt acattctttc gatttcataa tcttttataa atccatatcc
    11941 accgtgaagt tgtaatgctt tataagcaac ttcatttgca atttctgatg catagtattt
    12001 agccatagca gattcttgag caactctcat tcctgcatct ctcttttgtg ctgcatcata
    12061 aactaatcct ctagctgcac aaacttttgt ttccatgtca gctatagtaa attgagtatt
    12121 ttggaattta gctataggct taccaaattg aactctttgt tttgtatatt taacagcttc
    12181 atctaaagca ccttgagcta ttcctagagc taaggcagca acacctattc taccaacttc
    12241 tagagtaccc attgctatct taaatccttg accttctttt ccaagtaagt tttcttttgg
    12301 aactttaacg ttttcaaata ttaagtcaga agtttcagtt cctcttatac ccatcttatc
    12361 ttcatgagct cctgttgaga aaccatccca tttactttct actataaacg ctgatgttcc
    12421 tctaagtcct ttacttctat ctgtaactgc tattactata gctacatcac agaatggtcc
    12481 attagttatg aaagtttttc taccatttaa tatatagtgg tctccaacta attctgctgt
    12541 tgtttgttgt ccacctgcat cagaaccagc tcctggctca gttaaaccaa atgctcctat
    12601 taattcacct gttgctatac cttttaagta tttttgtttt tgctcttcag taccattgta
    12661 aagtattggt aatgaagcaa gagaagaacc agctgtaaca aaagtagctg ttgaagcaca
    12721 tcttctagct atttcttcca ttactatagc gtaagaaaca tatcctgctc ccccaccacc
    12781 atattcttct gggatattac tgcttataaa ttttgcatca gctaattttt tgattaattc
    12841 cttaggcatt acacctgttt tatccatttc tgctggtaaa gtatctaatt ctttactaac
    12901 aaaatctctt actgcttttc ttaaaagttc ttgttctttg ttatataaca tagcttcctc
    12961 caattttcat attttatagt aaatttattt taatgaactt acgctaaact catcatctca
    13021 gcaaaagttt gaatacgagt tctggcttgt tcattattct gagtttgttg gtcgatttca
    13081 acatataaag taggtattcc actatcttct atatcttttc taactaaagg ataatcgtat
    13141 tcttctgggt cacagaattt catcatacag aagataacac catctatatc tttcttttta
    13201 acttcatcta ctataagtga cccacgtttt ttcttagggt cataagctaa tgaacatcct
    13261 tctatgtttg accattgtct tgctaatctc tctaacgcat catcacctgc tggtacatct
    13321 gttctgaatt gtcttgtttc ttgtgctaag tcgtcagcta caactgatat attgttgtct
    13381 tctaaaatgt ctaatatatc tttagaatca gctaatatac ctgttaataa aactttcttt
    13441 ccagaacaga cttcttctgg catagcattt aattttgcta ttaaatcttt cactagctca
    13501 gtatgttctt cttttctcat aaagaaccca ctcttaatta ctaagcttct tattgatggt
    13561 tttatagtat tagaatgttt ataagctact tcaacaaagt ctctcatagt ttttctatgt
    13621 tcattgtaaa cttctatact ttcatgaatt tttgcttctt ctatttcata tccacaaatt
    13681 tcttcaagtt ctctttttac acctttgtac tcactgatta agtattttac accagcttca
    13741 agttttctat tttgtgggtg tactaatgat atatatttta tatgaggtac tgctgatttc
    13801 cagttttgtc ctaaacaaat tagtgtatca cacatacctg gtataataac tccagataat
    13861 tcatcataag caccttttaa tccatattct aaacatgatt gcattattga acatgcaaat
    13921 gcagggaaat attgtttagc taaatctaat tctgtttgtc ctccccatat accaactgga
    13981 agcattccag ctgcatgtat aatttcttct gggcaataaa ctgggaaaca acctatagct
    14041 tttttaccag tttcactttt atattttttt acagccgcat ttggattttc aactacttct
    14101 ttcattttag ataaaatagc ttccattata tctcacctct attaagtttt tttctttctt
    14161 ccattacttc aactaaacct tgaattcttg tttcaaattg agcattagtg aaagctctag
    14221 ggtctgcttg gtcaccatca aatccagcat atggtaatcc agtttcttca gctgctcttc
    14281 tttgcatttc atattgtatt aaactcataa gtttacagct tctgttcata tgatagaatg
    14341 ctccatcaca tttaccctct actaaagaat caactctata ttttgtcata cggtctaggt
    14401 ttacattgtt aaacatagta ctatatgcta ctgccattcc atctaaatca ttaacttcat
    14461 attgtaatgc ccaagcatgt gggtaaacac tacctgtcat gttaactcca aatttagcta
    14521 atgttttcat cttgtatcct atatatggcc aacaaggtat accttccatc attattctgt
    14581 atttttcttc ccctctgaaa gaagatttac cagttttcat gttgtcctct aattcttcta
    14641 taagtaactt aaatgcttct gtagtttctt ttttacctct agcacaaact attacagcca
    14701 tgtaagtaaa taagtcaaat ccattcattg gagaaggaga agaatctgct ggtaaactca
    14761 tagaatactt ccatagtctt ccgttttcag ctgatatttt cattacttct tcaaacttct
    14821 tagggtcaaa tttctttcct gatataattt ctagttgttt tatagcttct tcaaattgag
    14881 ctttaatata atctattctt gattgagtaa cttcgtcttc attattgaaa gttgtatcaa
    14941 tcattattaa aggtatatct aattctcttg aaatattttc ataccatttt ataacttggt
    15001 tacatatatt gttacagcaa agtaggaaat ctggagccgg catatccaaa gcttcacatc
    15061 caccattttc taaaagacca aaatttgttc ttgcatatgc acataggtca atagaatatc
    15121 ctttagattc agctatttca cataattcta aagaaccttt tttagctgct actccagctg
    15181 cttggttttc tggatataat acgtttaagt caaatacttc tgctaactct tgaggaaata
    15241 ctgatgttga ccaacctaca ggtcttcctt cttctttagc tttaaatgca tttgcatatt
    15301 gttcagctaa taaatcatta attactactc tagcttcttt tttttcagac attttcatcc
    15361 ctctttttat atatttttca cttctttttg tgattctttt gcttcatcaa aagcatataa
    15421 cgctgctcct aaagcaccag ttaattgagg tatatcaggt acaataattt ctgtgttgat
    15481 ttctcttgcc atagctctta caataccact atttctagca actccaccaa ccataactac
    15541 atttctttgt actcctattc tttttactag gctagaaact ctctttgcta ctgaagtatg
    15601 aatacctgcc actatatctt caatttttgc attttcagat aaatgtgata taacctcaga
    15661 ctctgcaaat actgtacatg tactgcttat tgatacttca ttttgagaat tcatagatat
    15721 acttccgagt tcagatacat caacctctat tatttttgcc attacatcta aaaatcttcc
    15781 tgtacctgca gcacatttgt cattcataag aaagtttaat agtcttccat tattatctaa
    15841 ttttaatacc tttgcatctt gaccacctat gtcaataatg gttcttgtct ctggaattat
    15901 gaaatttacc cctctagcat gacagcttaa ttcacttatt tgcttatcag catctgaata
    15961 gttcattctt ccatatcctg taactacaac ttttttaata tcttctcttg caagacctgt
    16021 cttgccatat aatttttcta aaactcttga tggtccagta gtcccagtac cagaggatat
    16081 tgtttcagaa gctacaatat cttccccatt ctttaagatt actccctttg atgcagttga
    16141 acctatatct aatcccattg tgtacatctt tagcattctc cttttaaaaa atctagaatt
    16201 actaattaat atcttacaac tttactatct ttaaagttat ttattttctc ttcatcgtag
    16261 cctaaagatt ttaatacttc tacagtatgt tgacctactt ttggtgctgg tgtatattct
    16321 ttaattcctt catttctaaa cataactgga gtattaacta agacacctgt atttccgcta
    16381 tcgtatgttt tcttaaataa gaagtcattt gcccaagctt gttcgtcatc taataaatct
    16441 tcacagcttt gaattttttc aaatggtaag tctgcttctt ctaataaagc tgaccactcg
    16501 tctaatgttt tttctaacat agcttctcca actatcttaa ctaaatcttc aacatgatta
    16561 accattgaat ctatgttatt atatctatcg tcttctaata tatattctct atttataacc
    16621 ttacagaatt tgcctaacca cttgttgtat tgtattaaag ctaattgaat ccatcttcca
    16681 tctttacatt tatatgtagt cattaatggg ctgtttggat tttctcttga taaaggcatt
    16741 tcatttccgt attgtgctgt tgttatcatt gttcccattc catatatagc tgtatggaaa
    16801 agacttactg ttactctctc acctttacca gtttgagctt ttttatgtaa tgctgctaaa
    16861 cttcctgctg ctagtgctag acctgcatag tggtcaccaa atcctgctgc tgtatttgct
    16921 ggagatgttc ctttttccat aacagattgg ctaactcctc ctcttgcgaa gtatgcagta
    16981 tagtcaaatc ctggtttatc ttttaaaggt cctttttcac catatcctaa tatttgagag
    17041 aatattaatc ctggatactt atcttttatt tggtcataag ctatacccat tttttctaat
    17101 gcttgaactc taacattagt tacaaatatg tctgcttctg ataataattt atgtaatatt
    17161 tctactcctt cttttgattt tacattaata cttacaccct ttttatttcc attttctaat
    17221 tcaaacatag ggttttcatc atctgatgct ggagatttaa atgttccacc cataactctt
    17281 attccatcac cttctatagg ttcaatctta ataacctctg caccccagtc acctaacatt
    17341 tttgcacaac atggtgctgc gatgaaactt gaaagttcta ctactttaac tccttctaaa
    17401 agcataacgt tttcctcctt aatagtatca attataaaat ttcgattaaa tcactcataa
    17461 aatacttttt tctgatatta actgtctgat gtcaaagttc ctaatcttat ctaaaataac
    17521 ttaaaaatta ttaaaattat tttttattgt tttattgtct tacacctata ttgttaagca
    17581 tttatcgtgc caactttata tttaatcaaa atatcgcttg atttgaatgt tttttaacaa
    17641 tatgcaattg aataatcttt ttcatatcgt ggcatcttgc cactatccat tgcattttgc
    17701 tattctttct atgcttataa aagttttttt tatatatttt tttatgaaaa agcttgacat
    17761 ttcaaaaaaa gttttcattg ctaaactcaa aaacacatgt tatcattgta attaatcagc
    17821 aagttagtta actaatttca aacttagata attttttaat aatatttaat ctaaaaaata
    17881 acaatttctt tgataaattt tagagtaatt attacattaa ataaaaaatt actaaatatc
    17941 aaaataacac agggaaaaca atttcaaaac taaattttta accttaaaaa ttttgtataa
    18001 aaaatataac cttatatgct acatattatt tctaaatgaa aaattaccat aataatttaa
    18061 taattacagg agggtattga tatgaaaata ctagtatttg gagcacgcga ttatgaagaa
    18121 ccagtaataa aaaaatggtc tgaagaacat aaggatgttc aagtggatat ttatcctgaa
    18181 aacatgactg aagaaaatgt agttaaagct aaagggtatg atggtatatc tatacaacaa
    18241 actaactata tagataatcc ttatatttat gaaactttaa aagatgctgg ggttaaagtt
    18301 atagcttcaa gaactgcagg ggttgacatg atacattttg atttagttaa tgaaaatgga
    18361 cttatcgtta caaacgttcc ttcttattca cctaatgcaa tagctgaatt agctgttact
    18421 caagctatga accttttaag aaagactcct ctagtaaaga aaaaagtctg tgaaggtgat
    18481 taccgttgga tagctgaact tcttggaaca gaagttagat ctattacagt tggtgttata
    18541 ggtacaggaa aaataggtgc tacttctgca aaattattca aaggcctagg agctaatgta
    18601 attgcatttg accaatatcc aaatagtgat ttaaatgata tattaactta caaagattct
    18661 ttagaagacc ttctaaaaga agctgacctt ataacattac atactccttt acttgaagga
    18721 acaaaacata tgataaataa agatactcta gctataatga aggatggagc ttacatagta
    18781 aatactggcc gtggtggttt aattaataca ggggatttaa tagaagcact agagtcagga
    18841 aaaattagag ctgctgccct tgatacattt gaaactgaag gattgttctt aaacaaaaaa
    18901 atgaatcctg gagaattaac tgacccagaa ataaataaac ttctttctat ggaacaagtt
    18961 atattcactc atcaccttgg tttcttcact agtacagcga ttgaaaatat agtttattct
    19021 agtttaagta gtgctgtaga agttataaaa acaggaactg ctactaatag agtaaattag
    19081 tattttataa atatattttt tcattaatta gctattatct aacaaaatag cctttaattt
    19141 cccaaatata agagagtcag ctcagtatat attgagtaga ctctcttata ttatttttta
    19201 tattaaactt gtactcttct tattcatacc aaattaaatt tatattaact tactctaact
    19261 actcctactc tatacatttt acctattttt acttttctaa ttatatacat ttgaatgggt
    19321 acaatctgta ttttacaaaa aaaacaccta acaaactatg aaaattgtat gattaatatt
    19381 aatatattta taagaaaaca taacaattat gttagctctg gatttttagg gagggagtat
    19441 attggaaaaa atgaataaag ttacttctaa aaaaactacc tatattgtta cttcagcatt
    19501 atttgcatcc ataatatgcc tgacaatagc atatatatta catattccag ttggtggaaa
    19561 caatggatat gttcatatag gagatgcttt tatttatcta gctgcaacta ttttgccaac
    19621 aaactatgct atagctgctt ctgcaattgg tgctggtcta gctgatttat ctacaggtgc
    19681 tgctatctgg gtaataccaa ctataatcat aaaaccaata cttgtattat ttttcacttc
    19741 taaaagtgac aagataataa ataagagaaa tatagttgct tcggttgtag caggtatagt
    19801 aggattagtt ttatacatgt ttgctgaagg tataattatt ggaagtttta caagtgcatt
    19861 tgtaatgagc ttacttggct tattacagcc aataggaagt tttattgttt ttataatctt
    19921 aggtatggca cttgataaac ttgattttaa aaaacgttat tttaattaag aatttaaatt
    19981 tatggaggga aaattatgaa tatcttatat acaattgaaa atagtatcta tgtaaatata
    20041 actaatacat gtccatgtag ttgtgttttt tgtataagaa acgaaaaaga tgaagttgca
    20101 aatagtggta gtttatggtt ggagcatgag ccaagtgtag atgaagtaaa agaagccttc
    20161 aataaataca atttagacga ctatgatgaa atcgtatttt gtggatatgg cgaaccatta
    20221 atgagaataa atgaattgat agaggtagca aagtttataa aagaaaaaag tagcataaag
    20281 ataagaataa atacaaatgg tctaagtgat ttaatacata acaaaaaaac agctattctg
    20341 ttaaaaaatg ttatagatgc agtatcaata agtcttaatg ccccaaataa agaagcttat
    20401 aatagagtta ctcaaccaaa gtttggagaa aaatcatttg attatatgtt agattttgca
    20461 agagattgca aaaaatatat aaaagaagta gctttttcag tagtagatga aatatctcca
    20521 gaagaaatag aagaatctaa acaactggca aaaaaacttg atataccatt aagggttaga
    20581 cataagaatt agcaagtaaa attataaaac attaagaatc acctgaatgg tctttcaggt
    20641 gattcttcct cttgtattaa cattttacaa aatagatttc ataccacact aggaatgtgt
    20701 aaatcatcca aatctttctc caattatcag agtttccact aatgtagtca ttaaaaatct
    20761 cattaatctc atctatgtta aagaatttat ctgctatctc actattgaat ttatctcgga
    20821 tatccttatt atattggtca tcagccatcc atatacgaat tggcacaata aatcctaatt
    20881 tatttctaaa agcaatctct tctggtaatg tttttgatgc agctgtacga aaggcaattt
    20941 tattctcttt tcctttcact ttatattctg atggtattct ggatgcaata tcaaatattc
    21001 ttgtatctgt aagaggcatt ctgacttcca atcctactgc agtactcatt ttatctatat
    21061 taaaataaat atctccttcc aaccatattt gaatatctac atttgacatg ttagtaagtg
    21121 tatctagttc ttctgtttct tcataaattc cttttaccac ttcaatagga agcacatcag
    21181 gattgtattt cttaagaatt tttcttttct caccctcatt cataatgttt gtatttccaa
    21241 tataaaatgt cttcaaattc tctccataac actctgcctt atggtatata ttatatccac
    21301 caaaaaactc atctgctcct tctccagagt aacagatatt tgtgttttca gctgctgcct
    21361 tgcatccaat agcaaaaacg atagcagatg catctccagt tggttgctcc atatggtaca
    21421 ttacataagg tactgacgca aaatactctt caggtgtaat tatatatctc gaatttttac
    21481 acccaagaat attagctgtc tgttgtgcta attttgattc atcaaaacgc tcttcctcat
    21541 aaccacatga acctgttttt tctatatctg acattgccaa tatataagat gaatcaacac
    21601 ctcctgatag gaataactct gcagtttcat tctctgattt tacctctggc ataattttct
    21661 gaagtgttgt atgaatttca tccgtccatt cctcaataga cttgctgtgg tcaggatgaa
    21721 attcaggttt ccaataacga ccaatacata ctgttttatt ctgatagaca aggtaatgtc
    21781 ctggcataag cttctttact ccacggaaga atgtattttc acctgctaca tatgtgaaag
    21841 acatataaat ctgtaacatg tcttcattta actctttcac aaatcctggt tgctccataa
    21901 tcttacgaat agatgaacca tagagaagct tcccattttc agtctcataa taatagaaag
    21961 gttttacccc aaactggtct cttaggcaga agagtttctt ttccacagta tcccataatg
    22021 caaaagcaaa cattccatgc atgtgatttg ccatatcata tccccatgtc ttatatgctt
    22081 ccactaaaat tgctcgttca cgctcatctc tacataatga agaatcgatt ccaagttctt
    22141 cacaaagaac tttccagttt cgaatatgcc cattgtattc tagaattttt atcatatatg
    22201 tgtcttttcg tgttaaatac ttttcttcta aatttatcat atgtgtatcc tttcgtatta
    22261 aaacatttaa cttctaaatt tattaaatgt ttatatatat ttattcactt ataatcactg
    22321 aaaaatcgac ttttttcaaa gtaaattctt tttgaattag tactaatctg ctctttatta
    22381 atggcataaa tatgattatc aagtattatc agtgttataa cattgaattt tttattcttc
    22441 ataaatattg ccccctttat attaccaact aaatataata tatcttatgt tacttacata
    22501 ttctttaaga aattctgaag attttataaa gttttttgta ttataattaa ttaaaaataa
    22561 aattctagtt ataaaacata ttttccatta aacaaaaaaa tagttaaaat aaattcataa
    22621 ccacataaac ttattttaac tatttgtata ttttaattat aaatattaac ttaaattttt
    22681 aacaggatac actcataaaa taaacataat gaacaacaaa ataatatgtc tcagtttctt
    22741 tatatacttt accttctttc aattttctac catgtagacg tataagataa tattagtaat
    22801 tcactctatt gcttaactcg tgcgatatgg acaaccaaga aagctatttc ctcatttgtt
    22861 aacttttttc catatttctt ttctaaaaaa tctctaactt ttaatgcaat taacatttct
    22921 tttggatttg accttttcat ttgattaaat aataaatcat caccactgct taacatacta
    22981 tctgaaaaaa atctttccac aaaaaatttt atatgtgtta taaatctcat ataatgcata
    23041 ctctttttat ctaaggttct attcaaagaa aaaacaaaaa tattaattat ttctccaatt
    23101 actttggcat acttaatcgt atcatatgaa tttccatctg aagccatagc atttgcaaaa
    23161 tggaaagcaa tgttagctgc ttcttcctct ggtaattgaa tgcccaatct ctcctctacc
    23221 atataaattg caaccattcc aaccttaaac tcatttggat aataattttt tatttcccaa
    23281 aatactcgat ttgtaatttt tattccttta cgcatccttt caattgcaaa gttaaaatgg
    23341 tctgctaata ttaagtataa gtttttatta aaagatgagt tcaataactt ttctgcctct
    23401 actattattt cctgtgttat ctttaaaatg tcgacaggaa tatcatccat taattctaaa
    23461 aattgttttg attttgtatt ttcaacaggg acaaacattt gattatcatt ggaaccacaa
    23521 atatattctc ctgttttttt accatatcca attcctttcc ctagcaaaat aaattcatta
    23581 tcctttgtgt catgaactaa aacaacgctc gagttcaaaa ctttctttat tatgtagttc
    23641 attttatttg ctcaccttct attggtcatt taaaatctat actattactt tcaattacct
    23701 ttttatacca ataaaaacta tctttcttat atcgattata tgtccccttt ccataatcat
    23761 cagcatccac ataaatatat ccataacgtt ttgacatttg tttcgttgat tcactgacca
    23821 aatcaataca accccatgaa gtatatcccc aaagttcaac accatcttca ataatcgcat
    23881 ctaacataca tttaaagtgt tcttttaaat aattaattct atattggtca tgaacttttt
    23941 tatcttcagt taaaatatct ttggctccca atccattttc aactataaat aaaggctttc
    24001 tgtatctatc atataattca atcaaagata tacgtagacc tattgaatca atttgccaac
    24061 cccattcact catttctaaa taaggatttt ttacagctaa taacgtattc ccaggtgtaa
    24121 tatctaatcc agttgtatca gctgcctcac aagaagacat atagtaagag aatgaaataa
    24181 aatctactgg atactttttc ataatttcat catcatgttc ttcttttact atttgaatgt
    24241 tattattttt aaaatacgac agtaaatata ctggatactc accaaaaacc tgcgtatcac
    24301 tatatgcata aatacttctc atttttcgtt gagttgccaa aacatcttct ggtctacatg
    24361 tgtatggata atacgttaat tttgttaaca tacaccctac ttttgaattt ggaataattt
    24421 catgacaaat ttttgttgca agggcactag ctacaaattg atgatgcata gcttgaaaaa
    24481 taacttcctc aaagttttta tccttaaaac ggtctcgaac taaaccacca gtagtgtacg
    24541 gatgacgaat catagaatca acttcattaa atgtaagcca atatttcact ttgtttttat
    24601 atctttcaca gatagtttct acatacctaa caaacatatt gataacttgt cgtgaatacc
    24661 atccatcata gtttaaaacg atatttaatg gtggttcata atgtgacata gtaacaagtg
    24721 gttcaattcc ataacttatc aactcatcaa atacatcatc ataaaactgt aaaccttctt
    24781 catttggctc tttatcatct ccatttggaa aaatacgaga ccaagcaata ctcattcgat
    24841 atgtcttaaa tcccatttct gccattagag caatatcttc tttatagtga tgataaaaat
    24901 cactaccatg acgttttgga taatttactt catcttcagg atgtgctaat ccttcttcta
    24961 tatcttttgt tgtgatttca ttattagatt tataatcttt cacatctgca tcaaagtgtg
    25021 cctttgctac atctgataca gaccaccctt taccacctaa attccaacca ccttcaaatt
    25081 gattagcagc tgtagctcct ccccaaagaa atccttctgg aaactttctc atatttatat
    25141 tcctcccttt acatcaaaca agatacttcc tttttttaca ttgccataag actggtttaa
    25201 cactttataa gcataatctg ctccattatt gtttacaatc ataacagttg aatctaaatt
    25261 agcatgtgag attttgtcta aatcaaactg aattaataaa tctccttctt ttacattatc
    25321 gcctgtctta acaaatgttt taaatccatc tccattcata cttacagtat ttattccaat
    25381 atgaatcaaa atctcagccc cattttttgt tcttaaacca attgcatgtt ttgtttcaaa
    25441 taacatcaca acttctgaat cacaaggtgc gtataaattt ccattggtcg gtataattgc
    25501 aactccatct cccaaagtct tacttgcaaa tagttcatca ttaaccttac ttaaatctat
    25561 tacttttcct tctactggag ttactaagat atttacttct ttttcttctt ctagctcttc
    25621 ttcaacaaca tctccaattg atgactctac tgtatttgta tcttccttcc aaataatcag
    25681 tgtaataata aacgagccta atattgcaat aacaaaacca atacttgcaa aaatcaaatt
    25741 gtttccattg tttgggtcaa taaacatact catactggca agccctggtc caacaattac
    25801 aaatcctttt actgcaaata atcctaaaaa tgtaccagaa attgcacttg agaatacaac
    25861 acctaacatt gctcttttat gttgtaaagt aataccatat aaagctggct ctgtaattcc
    25921 catcaaggca gaaattcctg cagataatgc tgtttgtttt aatgtttcat cttttgttcg
    25981 caaggctact gcaaaacaag caccactttc agaaatattg tgggctaatg aagatgtcat
    26041 atataaagct tcataaccca actttccaat tgtattaatt gaataaggta ttagtgcttt
    26101 gtgcattcct gttgcaacca taaatggaag aaaagcagca agtaatccta caactaagaa
    26161 tcccattttg ttatataaga ataaaataat ggttgtaaaa attgtaccaa cgttatatcc
    26221 taaaggacct aaaatagtta gagtaattgg aacagtaatt gccaaagaca tcataggaac
    26281 aaagaaagtt cgaattggtt ttggtgaata cttgttaaaa attttctcca ttgttgccaa
    26341 gaaagacaca cataagatag ccgggaaaac ctgtgcatta taggcaatgt ttggaattgt
    26401 aaatccaaat agttcgacac cttcacttaa agcagttgtt gttgctggaa gcaataagta
    26461 tcctacagcg gcaatagcta ctaaacgatt acatttcaat acattggcag tagttacagc
    26521 taccataaga ggtaggaaat agaatgttgc atctgaaata gcaactaata atgtatatat
    26581 agtagaatct gattttaaaa tattaaacat tgctaataac atcaacagtg attttaaaat
    26641 accagctcct gcaatagcaa aaatcagtgg ttgaaaaata ttaataataa attctataaa
    26701 tcttgttcct aagtttattt tttcttcagt ttttacagta ctatcatttg tatctaaagg
    26761 gcaaactttt aaaatttcat catacacatc aacaacacta tttccaatga caacttgaaa
    26821 ttgtgcccca ttaactatac tcataacacc ttgtactttt tttaaagcat cctgattgac
    26881 tttacttcta tcaatcaact taaagcgtag tctagttgaa cagtgttcta aagctaaaat
    26941 attttttgaa ccaccaactt gttcaataat gtcaatggca gtttttttat aattcatctt
    27001 gtaatctcct tctccataat tttttatgaa tggccattca agatgcaaaa aaggcagaac
    27061 ctatataaac accttgaaaa atcaaagcaa tatattcgat cctgcctgca ttaccagtaa
    27121 catgtcttct atttatacta ttttgtatta ttatattaac atttgcctaa aagaattgtc
    27181 aatacttttt taaattttct gatactaact aatagcacct ttataattca ttttttatat
    27241 caattaaagt aacagtagcc acccaccaat tagtatcaaa attgaacctg gtattttttc
    27301 ttttatattt tctttgaata taaaatgagc aagtattaaa gttattatca tagatacttg
    27361 agaaaatggc tctgctatac taagttctag attatttaaa gcaattaata atgctaaata
    27421 agaatatcca ttaatagcac cacttaaaat tgaaagcccc tttttattac taaaaatctc
    27481 acaaattatt ttttgtttct ttttaaatgc taaaaagata aataaattta aacctacgaa
    27541 aaaatacagt atagttgaat ataatatagg agatacttgt acaaaaaaag ccttatccaa
    27601 tactcttcct actgactgca aaaatatgta taaaaacatt aatctacatg gtaaattgtt
    27661 aaaaattaca gagacattct ttaaaaaaga gcttactttt tttaatataa acactccacc
    27721 aatcataatt atgattcctg caacttttgc taaacttaaa ccttcaccta aaaatataac
    27781 tgataaaagc agtaaaaaca atgaatttaa actatttatt ggagtaacaa gtgaaacttc
    27841 cccagttgct aaagacgtta catacgctac tgaaccaatt gaatagacta aactacttat
    27901 ataacatggt attaaaaacg accaatcact aactctatcc attatgctaa atggaagtaa
    27961 acatactccc cctataaaga aaaatagaaa tgatgaagct atatttttat aaatatctcc
    28021 ttcttcatca cctaataatc ttacaactac tctttcaaaa gctaatagca ctactctaat
    28081 taataatgca aaataagata atatcatttt tgacctcgct taaaaattaa tccgacttat
    28141 tgttatatta actgtataaa actaccatat aggtaagtct tttggatttt ttaatatttt
    28201 atgtttaaat acaggtacat taagtttttc acctagttta cgacattgct ctttataggt
    28261 accttttaat ttatcatgaa aaactataca atcaattcct ccttcaatac tatttataca
    28321 cttttctagt ttctcaaatc cagattcatc atcatacatt ccacttacaa tccattgatt
    28381 tggcaataca tgtccaattg atatgttata ttctttattt tttataatat ctgagaaaga
    28441 tttctcaaaa tgtacccctc caacacataa caaagtcttc aaaggttcat cacaatcaaa
    28501 tactctaatt aatgattttg ccaatacctg tattgctata ctattattaa aactatcact
    28561 actacttcct atctcaatat ccaacatagg tacagaatat tctgtaatta atttagattc
    28621 ttcaccatat gttgttccag accagtgagt tgcttctgtt aatgtagtaa attcatcaag
    28681 tagattttca ttttttatat cctcaatagc attgattaga tttttaaagt atcttggatt
    28741 tgaatttcca aattctcctg ttggaacatc tccaattgta tgagctgtta ggatatgttc
    28801 tggagcattt tctccctcat gccaatttac aactcctgca aaatcataat ctctaaaatg
    28861 tctatttaaa attggaagat aatatttata attatgactt attacatctt ttgtttttac
    28921 aaaatgaaat aagttattgt ttttatcctt aaactctaat acaaaattat catcaataac
    28981 aatatcagtt tgatttaaat ccattatttc ttcacaacat tttatcacat tactggctac
    29041 tgggtctttc tttaaatcac tgcaaaagaa aaaaactgct tttttattat tcatccataa
    29101 atcacactcc tataacttaa atataatata tcttcatacc taaaatcatc taaatatcac
    29161 tctaattcca ttaaattatt tatatataat atactaccat actcatttta gctatacctt
    29221 tgcctgagtt tctatatata tgtgatacat cagctttaaa tcttatagaa tttccactag
    29281 atacaatgta atcttctcca tttattttaa tggttacttc gccactaaaa acagttataa
    29341 actcttgtgt tcctggaagt tcagcatttg aatctaaatt tccaccttct tctatttcaa
    29401 tcataaatat ctcaaatctt cttttggagt caaatggaaa tattggataa cttatatact
    29461 ttccattatc ttcaataaaa tggtctatat cacttttttg aatcaattct atgtcacttt
    29521 cctgcctctc catcaatgat gtaaatgaga tttttagccc attagttatt ttcttcaaag
    29581 tagatatagt aggatttacc tcacactttt caatttgaga tagcatactc ttacttacac
    29641 cactaagttg tgcaatcttg tctaaactaa gatgtttttc tttccttatc ttttttaaat
    29701 tttcagcaat tatttcattt aaactttgca taaatacccc ctaatacata ctaatataag
    29761 ataaattatt ttgattatta aataaactta gtaatttaat agaaactttt tatccattat
    29821 aatgtacatt atgtttaata tacattactt tttttagaat gtaaatagtt ttctgaaatt
    29881 ttgtgaaaat gaataaataa aaaactagta acctatattt ttacaaggtt actagctttt
    29941 attataataa tctttcattt taactataaa acttagatgc acctataagc tgtctcttag
    30001 aaacaatctt agctaggttt gctaatgaag aaatttttat atctttaaaa gaaactaaaa
    30061 atacaaactt aaaatctgta aattcttgat ttatattgta tatatcaaaa taacatctca
    30121 aattatcaaa taagtaatta tcctgtaagt ctgcttctat ctcatcagta gcatctttta
    30181 aatacgctct tacatcttca aataaaacac tgaaataaga ctcatctatt tcttcaccta
    30241 actcttccaa tatttcttct atatctaaat catccatatc aaaagaattt cctgtcaact
    30301 ggcaatcaaa taccaatata ttttcttgat ttatagtatt tgatatatct tgtacatatt
    30361 cgaagtctgg acgtaattct aaaatgtctt ttatttcact gctctttaca tggatttttc
    30421 cttttctatt ttcaattttt aaatctatca tatgctcccc ctttcaatct acaaatcttt
    30481 aaataccttg ttttataatc ttttcaatat ctatccaatt actaactcta actatatttt
    30541 gatgtttaac atctttatta tagttagtat ccagaagtat tactttaaca ccatcatcag
    30601 ctagttgcac tgagtttaaa ggattatctt ctataaatat gtcacaactc agttctcttg
    30661 ccttttcaac tttataatca cttcctaata agtaaacatc tatatctgaa aatccttgtc
    30721 tcgatagcca atttttagtt acatcagtta aacactcatg tctagccgtt acaaaagata
    30781 aattatgtcc tttagataat gtgctaatta cctctgtagc accctctaca atctttgctt
    30841 catcatatga gtgtatatac ttattattaa actccgcata cacatctctt attcccgaac
    30901 catacaattc ttcccaatta tgtgttatac actctgcttc agttatattt ttattaaaga
    30961 tatcatttag gtatggaaga aaatgataag ggcttgttat tgttccatct atatcaatac
    31021 atatattcaa tttgttcatt tttacctcca tgtaacattt attgatttga ttaatcaaat
    31081 attatagcac agctttaatt ataaatcaaa actctggata tgactatacc tatataatac
    31141 caaaaagctt gcatatttaa gcaagctttt cgtaaatttt acatttttaa ctaatatata
    31201 agtttttcta aggttggttc cactccaaat tgtgatttca gttctttata ttcttttaat
    31261 gctttgtcat tattcgtttt agtttttatc gctcttatca ttaaattttt tggtgtatca
    31321 agtggagata tgtattctac tacagaagta tcatatccat tgccctccaa taacaatgtt
    31381 cttaaaccat cagttattaa atctgcaaat ctagctttaa atacaccatg ttttaatatt
    31441 ggttccatag cttcatatct atattgccct aatagctcct tatgacaaca tggtactact
    31501 actatagctt cagattttgc tctaattcct agacctattg ccatatctgt agccgtatca
    31561 caagcatgta gacttattac aaggtcaaca tccctattag gtgtataatt agtcaaatcc
    31621 tcttttataa atgacatatt tttataaccc aagtttttag ccatattttt tgatgcttct
    31681 ataactacat ctgaataatc tattcctata aaataacagt ttttcttcaa tacttctttt
    31741 atataaaaat ttaagacaaa gcttaagtag gattttccac aagcacaatc caagatagtt
    31801 atacagtctt tatcctttat ttcttttaaa atactatcta tcaattcaac aaaatggtct
    31861 atctgattgt attttcttat tttatcattt tttatcttac catcttttgt aagtactcca
    31921 atttctttta aaagtgcatt tgcttgtcct acttttacat aataatctct gttttttatt
    31981 tgagatgccg taaattcatc tattttaggt acttcttcct tattatctaa atattttaca
    32041 tttaccttct tattgtctcc ttcaattaca acaatagttc ctcgctcaac atatttaaat
    32101 actaatccat cataattttc tgcctcttta gaaatattct taagcaactc attaaacgta
    32161 tataaatctg attttccttt aaaattaaat ttatatttat tatcttcctc tattgcaatt
    32221 cctttaaact cttttcttcc agatttaaaa atcacctcta actcaataaa aaaatcccta
    32281 ttatcaaggt ttctttgagt aatccccata aaaaacatat ttagttttcc tatactctgt
    32341 ttattcatca taatctccct tttaacttat atccttaaat cttattaatt aatattattt
    32401 gtttctgaat tatttatttc ttcttttaaa tcgttcaatc tatttttaaa actttctatc
    32461 tgcttatctg ataaatcaag atattctgtt atcttcccta tatatttagg gcttttagta
    32521 tttattaatt tcaaagcact ttccatagat ttttctctaa gctcatatgc tttctttacg
    32581 tcatctctag cattactcaa tgtttctgta tacttctcct tagaaagttc tggaatctgc
    32641 atattttcat attcttttac aacttcttta cacttgtttc tggcatttgt aacatctttt
    32701 tttatactag ataatttagt tatatttttt gctatatcct tagtgtaagg tatgcattct
    32761 ctcattggaa ctaaagctgc tctttctata ttataaattt ctttcttaaa aattcctata
    32821 ctttccatat ctattttttt tatatcttca ctattttttt ctttacttgt atatttatta
    32881 ttttcttttg tattatcttc ttgtttttct gatttattat tcactgaaac attactatca
    32941 gaattattct tttcttttat atcattactt ccttcttcat tactttcttt attttgtata
    33001 tttctatctt gtttgttgtt taaattttta ttatttgata tttcttcatt ctttttatta
    33061 tcctggttta aatcagtact ttctttttcc ttaaaatttg atacatactt ttcatcatat
    33121 gtctcatcag aaatataatt gtgataatac atagactctt ttattttatt aagtccactc
    33181 atataaatat tacttatcat tattgttgta gctaatacca cataaatact actgtagata
    33241 caagacctct taaaattctt gtaatttctg aatatcacta ctaaaggaat aagatataaa
    33301 aatataaaaa ctaatatcca cctcataagt cgtgtctcct ttctcaaaac cgaaatccct
    33361 caaatattta tttttaatca tgtatcttat agtatttacc aatttatgtt ttttaatcgt
    33421 gaacttttat taaattaaat tctgtatagt cacaagatgc taatgtatat tctactccat
    33481 ttcgaatccc cttcaatccc attttaaaag attctttacc atgcaagtga ccataaatca
    33541 ccttttcaac attatattct tcaaataact ttgtaaataa agattcttcc aatttatcat
    33601 tcgtaggagg ataatgagta atcacaatta tttttgagtg accactttta cgagcagatt
    33661 ctaatgatag tctaagtcta tgttcttctc ttttataaac tttttcatca gtctcatcaa
    33721 atttaacatc attaggacat atccagcccc tacctccaca aattgcataa tctttatatt
    33781 cataaaaatt tgtctgaata aaacgcatgt cttcatatag cttatttaaa cttgtaacgg
    33841 ttgtccacca gtaatcatga tttcccttta taagtatttt ctgacctgga agtttgctta
    33901 ttatatctaa atctttttta gcttcggata aattaattcc ccaagatgta tctcctagta
    33961 ctaagaccat atcttcttcc ttaacaactt ctttccaatt atctataatt ttcttttcat
    34021 gaccatccca attacttcca aagatattca ttggcttatt gactgatgtt gaaaaatgta
    34081 aatcacctat agcatacaaa ctcataatat cattcctttc ttaattacac taaataggct
    34141 gtctcttttt agaaattatt ttccattaag aggcagcccc attaatattt agcaaatttt
    34201 ctacaagtag tttttactga actactttat catctacctt agtatcctta tattgctcta
    34261 ataatatatc tatttcttgt tttaattcca aaatttcagt tatattttta tctgtttcag
    34321 ttctatcaag ttttctttgg tactgcatag ctttatgtgt atcacccaag tcatataact
    34381 cttgtattct atttagagta tctctaatag ctatagactt catttggtac atagcctgag
    34441 ctttcattat gtcctctctt atttcactca tttcttggtc taaaagaaag gcagcatcag
    34501 atgctcttct aagcctttca gcaagagtct caggtatgta atggtcatat ttatatttta
    34561 atgaatgttc tattgtagcc cagaaattca ttgcaagagt tcttatttgt atttcacata
    34621 taatttcctt tgaacccgca atggagttta tagggtattt tattataaca tgatagcttc
    34681 tataaccact atctttgtaa tttgtaatat aatctttttc tcctattata gtcatatcat
    34741 ttcttacttt tatcaaatca actatagcat atatatcctc aacaaactgg cacattattc
    34801 ttataccagc aatatcatca atttcagttt ctatatcttt tgcatttatc ctttttaact
    34861 tagatattat ggaagatatt ttttttgttc tacctgtgac aaactctatg ggagaatatt
    34921 caccttttgc taaatattct tttcttatat ttttaaattt tatttttaat tcctctactg
    34981 catgttcata aggtgctagt atctcattcc atttttcgta ttccatattg ctcacccttt
    35041 atttgttttt tatgaccttc tttattttat cataatttat tttgtttttg tatagtaaag
    35101 caattctcca ttttccaata tataccctat ttcttctaaa tcaactaagt aacttatgac
    35161 agatactaac gaagatttaa aaaaatgata ctctttataa ttattgctta aattattgtt
    35221 atttataatg ttttttaata aaatttctaa agatttcggt tctacaagca actctcttat
    35281 ttgatataaa tattttttta aagcattcaa atgtttttct attaatttat aagaatcttc
    35341 tttcgatata acttgcttgc catgccctaa aactaagtac tcaaaatcta tattttttaa
    35401 tttttctaat gaatttattt gttcttgtat atcatataga aacaagaaat cgtattttga
    35461 taaaatttca tctcctatca ataaatcgcc aacaaaaatc acattatcct tcgtcaaaac
    35521 agctatacta ccaggtgtat gaccctgaaa ttcaattata tcaaacattt cattgtttaa
    35581 ttcaaatttt ccagcttcta taaatttatc tatttttata tcatccaaca ttttattttt
    35641 taagatatta tccataaata cattgctctt tcccccaaca atatactttg aaaacaattc
    35701 tggattttct atatataatt tatcgtattc agatgacatt atacacacat ctttataata
    35761 ttctttaaat tgattacaag ctccatagtg gtcatcatga ccatgagtat ttataatata
    35821 tctaacctgt atattatttt catctaatac tttatttact ctcctaggtc ttgaaccaca
    35881 taaccctggg tctatcataa gtgctgtgtt atcttcaaat acatatattc ctgtattcgt
    35941 gccacctttt ataaaaaagg tatttccttt tacttttgta agattcacct tcttcacctc
    36001 attttgacaa tatttatgat acaatttatt acttactaat ataaaactat acaagaacaa
    36061 tcctttttat tctatctata gttctttttc ttattttgta ttctttagat atccttattt
    36121 tcacattata tgctaaattt ctataaagta atgactctat aaaatattca actatacctc
    36181 tatccctaaa gtctatatct atatttccac ttgaataaat atttgagtct aatatcataa
    36241 gctcatcaaa aaagcttaat ctcttagatt tacttaaata atctttattt ggaataaatc
    36301 tatcacaata atctatcctg taatttacta cttcatcatt tatttcaaat ccatattgct
    36361 ttttcattaa ctctctatag ttattatttt tctcaataac attatctaaa tttttattat
    36421 aatcctcttt tttccaatgt ccaaacatcc tacaatttaa tggtctaact tcatatatta
    36481 aacatctatt attagtatct ttaaatggac atgggttctt tcttgtatac tcctcaaaat
    36541 aataatctaa tattttactt atacagcttt tttttaaatc aactctatct tcaagataac
    36601 aaaatatatt caaaaactca attaaattta tacctactga ctccatacaa caatttccac
    36661 atccagaaca atttcctact ggcaaggact tatatacatc atttagtttg tcaaagagct
    36721 tatttttaat ggaataatct atacaattta aaatatcttt attttttata ctagtcatta
    36781 ttattactcc ttgttataat tattaagtta atacaaacaa ttattataac atatttttta
    36841 aatttaatcg catatggagg tattttatga atagatatac aaaaataatt aatatgatgg
    36901 gaagttatta cacaaaagac tttgaaaaag aaaaaaagaa tgtaataaaa gttagagaag
    36961 ttaaagaaga tacagttaga aaatttttct tacaaggtga ctgtgaagtt cttgtagtat
    37021 ttgaagacac tgggaaagaa atacttattg atgacttttc tcctgaagaa gatatcaaaa
    37081 aatatttagg agcaaaattt ataaataaaa aaagatagtt atcaaaaata attctaaaat
    37141 taaaatttaa taaatgtaca gttataattc tatataatta tagttaaaag ttatctttta
    37201 ttgctttttt agactttaag atagcttttt ttctattttt tgtaaaataa ttccataatt
    37261 cacattaata attcacaaaa tgatataata taacaaatag ataaattttt aaatttctaa
    37321 atacataatt aatattttgc gaggtgattt tatgcaaatt tattttagag ttaaggctgt
    37381 tggcaaacgc aaacctatgc tagaacttac cccttttgat gtatctgaca acatcaattg
    37441 cctaaaagaa gctatctctg aaattgtatc taaaaatgtt cttgaatata atgagaaaat
    37501 cccagaaaaa tcaataataa acttcttaac taatgaagaa attgaatctc aagctgatat
    37561 tggaaaagtt ggatttggct ctatttacaa tgagaataaa caatctgtag aaaaggcaat
    37621 agaggtagcg ttacaggcat ttgaagatgg aatctacaaa gtgcttataa atgaagatgt
    37681 tattgaaaaa ctcgattcct ctataaatct gaaaagtgga gatatattta cttttataag
    37741 acttaccttg cttgctggaa gaatgtttta aaataaataa tttggaggta cataaatgtt
    37801 agaacgtact agagtagaaa aaaatcctaa aataattgaa aattttaaaa ataattttac
    37861 taaatcttct tcaaaacagt actacgactt agcaaagtct ctttgggact gcatagaaaa
    37921 tagttcatac tattatagag aacctgaaga caaattctta aatatgataa agaaatacta
    37981 caattgccac tactacgaaa ttaaaaatat ggacgagctc ctttctggac ctttaaaaaa
    38041 tgcattagaa ttaatattta cttctgaaca agtagaagaa ctttgccaat taattaaaag
    38101 aaagatggat tatacatatt caggaggata ttatcgtaaa gggtatcgct caaataaact
    38161 tgtggattat tttagaggta ttataaggtt tatttcaaac tatgttgatt taatttatta
    38221 tgatttttca gttatagatt atcttactct tccaaataag gtcttgtact atgactctat
    38281 aatgagtgat aaaatagcac tagaaataga caaaggaaat caaaaagtaa taagtgcttt
    38341 agaagaagta atatttggag aaaatcaaac tgctctactt acaagacaaa tgataattgg
    38401 tatcatgaag agtcatagtg ataaatgcta tgaaatgctt tctaaacttc ttttggcagc
    38461 caaacaacaa gaaggactta gacagcaaat tgtagagagt ttagatgagg gtacaatttc
    38521 tgcatcaata tacatgttaa aaactatttt ggacaacaat ttagagcgat ttagttctgt
    38581 tataagagcc ttggatacat ggacaggact tggtttttca gaccaaaaac ctggaataat
    38641 acgtaaatgt ttagaacttt catataaatc attgactgat gaaaagttcc gtatagaatc
    38701 aattaatagc aatgataatc ttgaaattta ttttgcctta tgggctactg caacttacaa
    38761 catatatgac tcttactctc ttattgaaaa cttactttct tgtcaggaaa aatataaaaa
    38821 acttgtagct ctttactttt tatcgcatac agaaagtaca tattttaaac attctatagc
    38881 atctaaaaac attaagggtg atgatttaga gatactagca tgggtaatta caaatttcta
    38941 tgtagaaggt tctgttggct actactatag ttggcaaaac agagaaacta attttgactt
    39001 gtcaaacact cctattgaca aagactttga tgctagaaaa gaacaatttg aaagtttaaa
    39061 acatacttta gaaattttaa attcaaagac aaaatcattt tcaggaagtg tatttccatg
    39121 gacttggatt gaaatttctt ctcatgaaat acttaaatgt atgatgactt taacagcata
    39181 cgatatgaat gctcaattta tagatgtgct tatggaaaat tgtcatctta tgagttcaga
    39241 tttaagagct tcacttatag tcaattttgt aaatgaacca aagacagata gacaacgtga
    39301 atttttattg gaatgtttaa gtgataagag tgtttccaat agagaaacgg tattgagtct
    39361 acttagaaag cttgagctaa cagatgtaga attagataag ataaccaatc tattgtcttt
    39421 aaagacaagc tctattagac aaacagtaat aaaaatttta cttgaacaag atgattcaaa
    39481 tttggaaaat attgcttctt cactgataaa atcttcaaat tctcaaaaat gccttggagg
    39541 tcttgaaatt gtaaacttat taaaagacaa tactgctaga caagaactat ataataagct
    39601 tgttttactt atagaagata ttgataaatc taaaaagaat acatctcaag ttcaaatact
    39661 aattgataat ttgttaggta aagcaaaaaa tgattactgc aaagaaaatg gttttggaat
    39721 atataaccct gaaaacaaag ttcaaattcc agaacaattt gattttaaag atgattctaa
    39781 tagctcatca aagcttaata aaattatctc aaatataagt ttatctactc gtgaggattc
    39841 tgtttctgta gcaacaaaaa aagaagcaaa aaaaattctc gatacggata taaataaaat
    39901 aataaaagtt tatgaaaaat ttgatgagct tattactgaa aatgcagatt atgaatatga
    39961 agttgaaaga tggtcaggta atgtagacaa agtactttta ggttattcta cttataactt
    40021 gactcctatt aaatataaag tttctaatga tactcttgat aattatccat tagcagagct
    40081 ttggagagaa actagtaaaa agcttgactt agattacaaa ttaatacttg atattttatt
    40141 ttatagtata agtacatgtg gatataatga aacagaaaaa agttggtttt catctatata
    40201 ttcaaatgtc cttgactcta aaaaacaaaa taaaatatat acaaaacttg aaaaacttaa
    40261 atttaatgga cttacaagaa aacttttaag agttttacta aatgagtttg accataaaga
    40321 aatatttaac tattgtttag aaatatacta taaacttaga aacttattga ctatagaaca
    40381 atgtaaaaaa caaagagttg aatttactaa aaactattac agacaaaatg aatactgccc
    40441 tgctttaaat gcccctattt taaactattg gcttgataaa gcacattcgt ttatttatga
    40501 tgatatttct tttactaagt ttttctacac tacgttttca aattatcagt tgctagaata
    40561 taagtttcct ttctatacta gcataaatgt gtttgctcgt gcacatgaat taggattaat
    40621 gactgaagag caagttaata gagaaatgat aagtggatac aacgcatcaa atataataag
    40681 aacattgaca aatcctagat gggctggcga cacattagaa aagtaccctt ggcttaaaga
    40741 taatttaaaa actgttacaa accgaattat agaaattgaa tcacgtagag gtgatatgcc
    40801 aacagaggtg tctcatctag ctaataatat acaatacttt gaaggtataa attattttgt
    40861 aaatattttg gtcgctcttg gtaaagaaac gttccagaga ggatattcat atggtagcaa
    40921 ttattcaaaa aaagatgttt taagttctct acttaaaaat tgctatccta ctaaagaaga
    40981 tgactcaaaa aaattaaaaa gtttacttaa aaataccgac attactgagt taagattgat
    41041 agaatctgct atgtatgccc ctcaatgggt aaacataatt gaaaaatatt taaactggaa
    41101 gggtctgaaa agtacaattt ggtacttcca tgcacatata aatgaaggct tctctgcaca
    41161 aaaagaatca gaggttgctc tattctcccc tatttcacca cgtagtttca ttgatggtgc
    41221 atttgatgta gattggtttt tagattcata taaaactatt ggggaagaaa gattcaatat
    41281 actttacaag tcagctaaat atataactag tggtggtaac tctcatagac gtgcacaact
    41341 ctatgctgat gctacacttg gtaagcttga taaagacatg ttgatgaaag aaattgaaac
    41401 aaatagaaat caagataaat tgagaagttt ctctttactt cctatgaaaa aaggagacct
    41461 aaaagaagca actttccgtt atgaatttat tcaaaagttt gctaaagaaa gcaagcaatt
    41521 tggtgcacaa cgtcgtgaaa gtgaatcaaa agcttgtact atagcgctag aaaatctagc
    41581 tagaagtgct ggatttggag atgtaaatcg tatgatgtgg gctcttgaga ctgaaaaact
    41641 aaatgaagtt gctcatctat ttaaaccaaa agatattgat ggtacttcaa tttggataga
    41701 tgttgatgaa aacggaaaag catctactaa agttcaaaaa ggcaacaagt ctttaaagag
    41761 tataccaaaa gctattgcta aacatccata tgtacttgaa cttaaatctg tccaaaaaga
    41821 tttaaagagt cagtattctc gtgcaaaaca gagtttagaa caagctatga aaaatgaaat
    41881 agtatttaca gttaaagaaa ttgccaatat ctataaaaat ccagttatct gccctttgat
    41941 taaaaatcta gtatgggtat gtgatgataa tattggatat gtttataatg ataagtctaa
    42001 gttctttatt tgcaatatag aaggtgaaac ttataagttg acggcaaaaa ataaattaaa
    42061 acttgcacat ccagttcatt tgtttgaatc tggtaagtgg agtgagttcc aacatgattt
    42121 atttagtaag caaattgttc aaccatttaa gcaagtattc cgtgagtatt atagaataaa
    42181 cagtgatgaa ttatctgaaa aaactatatc tcgcagatat gctggtcacc aaattcagcc
    42241 aaagaaaact gtagcacttc ttagaaatca gctttggact gtcgattatg aagagggatt
    42301 acagaaagta ttttataaag aaaatatagt ggcaaagatg tttgcacttg cagattggtt
    42361 ttcaccagca gatatagagc ctcctactat tgaaacagta gaattttttg atagaaaaac
    42421 ttataaaagt ttagaattag cttctatacc tccaattcta ttctcagaag ttatgcgtga
    42481 tatagacctt gttgtaagtg tcgctcatgc tggtggtgtt gaccctgaaa ctagccattc
    42541 tactgtagag atgcgtatag caattgctaa agaactttta ttattattaa aaattaacaa
    42601 tgtcaatttt gaaggctctc atgctcttat agcaggtaat ttaggtgagt attctgtgca
    42661 tatgggttct ggtattgtac ataaaaaagg gatgggtgct ttgaatatac ttcctataca
    42721 ttctcaaagt agaggtaaga tattccttcc attcgctgat gaagacccta aaactgctga
    42781 gattatgtct aagatactat tacttgctga agatagtaag attaaagacc ctagtatctt
    42841 aagtaattta taagtataaa aactatccct aaaatatatt ggactttctt aaaaaaaatt
    42901 agaaagtcca atatatacta tactgtaatt tatatagatt aaatcataat tacaaataat
    42961 ttttatataa acttctctta tacattatct ttatggtact tattatatca cacaaaaagt
    43021 atttttcttc tatcttcact agaatctttt aaccctataa aatctatata aaaaatcttt
    43081 ttctagagat ttgtttaata tggcattttc ttgaaaattt ataaacctta tctctaatga
    43141 agatttattt ataggtataa ccttatgtat aaatcttaga tttactatgt attgtctatg
    43201 ggtcataaag aaattaggag gtaggcgttt ttttaaatca tcaaagttct cataaaactt
    43261 tattatatct tcatctttag tgtgtagatt aattgctctt gaatttttct caaacataac
    43321 tatatcatca aaattaatca tatgtatctg cttccttatt ttatatacaa aaagggtgtc
    43381 ttctataaaa ttattattag caatcttatg ggagttaata tggtctattg ctatgttaat
    43441 tgaatcaagt attttttctt ttttaaatgg tttaactaca aaatctatag gatgcacttt
    43501 aaagctttca agactataat cagcgaaacc cgtcacaaat actatatgta tatccttatc
    43561 tatagaaaga atttcttcag cagaatcaat cccattttta tatggcatat caatgtcaat
    43621 aatcaataaa tctattttct cattttttat aaattcaatt gcctctatac catccttaac
    43681 ttttttaaca taatctacat atccagactc tttagctata tttgctatat catctcttac
    43741 aatcttatca tcatcacaaa tcaaaacttt tatcatagac ttttctcctc ctaactaata
    43801 atattttggg attaagatta caaattcagt taaaaaatca tcactattta caagtatact
    43861 ataatcatac ttatctaata tatttttaac taaatgtagc ccatatcccc tatcttgtcc
    43921 ttctttagta ctaaatccat tccaaaatat actttcaaca ttatgtattt taggaccatt
    43981 attttttata gctataatat actgaaattc atcttcatat gcatgtactc ttatatactt
    44041 cttttctttt tttatagtag acaaagactc tattgcatta tctattatgt ttaatagtac
    44101 tgaactcata tcattaggtt caatctctaa attatccata aaatcttgaa tgtagacatc
    44161 aaaagatata tccttttcaa gacattcctc gtattttaat gaagctatag catctaaata
    44221 agatactttt ccataccttg aattttttga tttaaaacta tttgatatat tcattatata
    44281 ttctttggca tcttcatcta gcccagtatt taatagagaa tacaccactt gcaaatgttt
    44341 caaatagtca tgtttttgac ttcttaattt gataattata ttatccttat gatttatttt
    44401 actatctagt ttttgtagtt tatattcctg ttcattatta ttatttatca atcttataac
    44461 tttaaagcct gtataaaaac ttaaaataat taaaaccaaa aaaagtataa tatttaatac
    44521 tccttcaagt aaaaaactat atcctaacct taattgtata tatttagtgc cctccataaa
    44581 taaaatcaat gcaaaacacg atataaaaaa tgttaatatg cctcttttta atatgtctaa
    44641 ttctttgtaa aatttatact tattcattat aagattgcta aatataaaca aagttagtat
    44701 tactatagga aatacaaaat tgttagccat gatttccctc ccctctacaa tttatatagg
    44761 gattatatca ttttaaaaaa attatgtaaa aagttaaaat ttacatatag attaattaaa
    44821 cttgtaaaaa tacagatgaa tttgtacaat taactactta aaacttgaaa atacttactt
    44881 tgctatatat tttagataaa tatataattg atttagttaa gaaaggaagt ggtaaatatg
    44941 aaagataatt tgaaaatagt actaaggtat ataaaaagtt ataaagctag gtctttagca
    45001 attgttgtga gtataattct tgctacatca ctcgttgttg gtattggtac cctctcaaga
    45061 agtgctcagc aagcagatgt agatagattg aaaagagagc ttggaactga ccatgtatac
    45121 tttaaaaata taaagaaaaa tcaattaaag tccataaaat ctagcaaaga tattaaaaat
    45181 ctgggtataa catcttacta tgcgtctaca gatgttaatg aaaaattacc tataaacata
    45241 ctatatgcaa ataaaaatta tttgactagt cattctaaac ttataaaagg tcgatttcca
    45301 aaagctagca atgaggtggt agtcgagaaa tggattttaa atagtatggg cttaaaacca
    45361 gagataaatc aaaaccttac ttttaaatta tatcaaaaag aaaatccaga aacttttaaa
    45421 gttgttggaa tccttgaaga tagatttata gagaaaaaaa agggacaatg tgaaattttt
    45481 tctaatctca atgaatcaga actgaatgat tttacaactt atattgaatt taatgaaggc
    45541 agtgatataa atacaaacat agacaatata ataaaaaatg ctatgttaga tgagaaaagt
    45601 ataggaagaa actcaatgct tatagaatct actatgaaaa acggtacttt agataattca
    45661 agtaaatacg ttgcaattgc tatgagtcta tttgctggta ttgtaatata tagtatctat
    45721 gttatatcaa tataccaaag agtacaggaa tatggcgtct taagagctat tggttccacc
    45781 aactttagga ttttcaaact tatgctttat gaacttttca tacttgctct aatagcaatg
    45841 cctataggta tatgtatagg tatgggaggt gcacaaatat ttaataggtc tgtaggaaat
    45901 attcaatttg aaggaaatat aaatgttaca ccttttgtta ttccagataa aataattctc
    45961 ttatcaattg catgtacaat actaataata ctaattataa gtttctttac atacttaaaa
    46021 ataagaagaa tttctcctat tgatgctatc agaaaaactt ttggagctga taaaaatgta
    46081 accaaagtta attatttaat atcaaaatta actttaaata tgtcagtaac aaaatctata
    46141 tctgcgaaaa acatctttag aaataaaaag gggttcatta taattgtatt atctatgagt
    46201 ataggaggta taatcgtcat aaaagacaat tataaatatt cttttttaga tgtgcaaaac
    46261 aaatctactc aagaacaaac atatatgaat gcagatttta ttctatcaaa tgtttatctc
    46321 aatgaaattg gtaacaatac ttcttttaaa gatataaaag ggtttaatga taatcagata
    46381 gataaaataa aaaatataga tggaattgac aaagtcaaaa ctgctagtat cttaaacaca
    46441 agaatagagg taaataaaat aaatagatta gattactacg aagctataaa ttcaactcct
    46501 tattataagc taaatcctct gttcataaaa aataagacta ctggcaaata tacactaaag
    46561 caaaagctaa aaggttataa tgatgagatg ataaagtcat tagaaaaata cttagtaagt
    46621 ggaaatataa acttgaaaaa aatgaaaaaa gaaaatttag ctattgtata tgtaccagaa
    46681 atttctaaaa cacagaaata cacaaagact tttactcctg gtgaaggaac accagctgta
    46741 gatataaaag taggtgatac tataaaagtc aaatatccaa agggtgggat ggatacaggg
    46801 ctttatgaaa gtctaaaaga taattatgaa tacttagaat atgaatttaa agttggagct
    46861 attataagtt atccttttgc agataatggt atgtactctg gagatgatgg tgtagatgta
    46921 ataacgagta gcgaatacct aaaaaaatta actggtgtag ataagtataa cttagtttat
    46981 gcagacctta atgaaaatgc aaacaagaaa aaaataaata accttttagg taaaattgga
    47041 agtgaagttc ctggaactac aacagtagat atgatggtag aaaaagaaaa ttctgataag
    47101 atgacatcta gaactatgat ttatagttat ggtatagtag caataatgtt cataatcagt
    47161 gtacttaaca taataaacaa cataagttat aacttaactt caagaactag tgaatttgga
    47221 atgttaagag ctattggtat ctctgagaga ggctttaaaa atatgatact ttatgaagga
    47281 atattatatg gtgtactctc aagtataatt actatcgtgt caggaattat aatacaattt
    47341 aaaatgtatt atatgcaggg ctttgtatca tatggattgg gattttcaat agattacaaa
    47401 atatatatcc tagttatttt agcaaatata attgttggta ttctagctac atatattcca
    47461 tcaagaaaga taaataaaat tagtatagtt gaagctataa acattacaga ataggaggga
    47521 taattatgcc tatattggaa actattaatt taggtaagat ttatgggaaa aaggaaacat
    47581 ctgtacatgc actaaagaat gcaaatttaa aaataaataa aggcgaattt gttgctataa
    47641 ttggaccaag tggaagtggg aaaagtacat ttctacattt agtaggtggt cttgaaagac
    47701 caagtaatgg tactataaag gtagatggta aagatatatg ttgtctttca gataaagaat
    47761 tagcaagata tagaagacaa aaggtaggat ttgtctttca acagtataac ttaattcctg
    47821 tattaaatgt aaaggaaaat atagaattac cactaaagtt agacaataaa aaaatagata
    47881 aagaatatat tgatgacctt ataaatttat tgggtcttaa tgaaaggaaa aatcatcttc
    47941 ccaaccaatt atctggtggt caacagcaaa gagttgctat tgcacgtgct ttatctgcaa
    48001 aaccaagtat aatcctagca gatgaaccaa caggaaattt ggacagtaaa actacagaag
    48061 aagtcatgga tttactaaaa agttctataa aaaaatataa ccaaaccctt ataataataa
    48121 cacataatga aaatattgct agaaaagcag atagaattat atctataata gatggagagc
    48181 ttaaattaac actctaaaac tatttataga aaagaggatt taaatgttat tgattttagg
    48241 taatttaaat ttaaacttgg attttgacta cagaataata agagaagaaa atgatgatgt
    48301 agatatattt atagatatta attatcgtag cttagatata gatactgatg gttctaactt
    48361 atttaattct agaatacaat ttccatttgt aagagcattg attctaaggc taaataagaa
    48421 caatcaatgt atgacaattc atttgttaag agatatagat ttattctctg cttttgccaa
    48481 ctttgaagtg gattatactg actctataat aaatataaaa aatcaaaatg agaaagtaat
    48541 tttaaataaa tctatcaaaa aatagtaagg gggccttaat aggccccaat ttttttcttt
    48601 tctaaactta ttatatcatg ataaataaat tagtcaatag aattttctga atatttttat
    48661 aattttttca taaagttttt tatatattat gctttaaaat tatatgtaat aaaaaaattt
    48721 tccgactaat tttaaagtta attgattaaa tacacatatt cgaaattacc attaaattac
    48781 tgacttttta tcatttccat ttagaattta agttataatc tattatttat agttacttct
    48841 acgtgtctct aataaaactc tatttatatt caaatctaat aatttatata caaacccaat
    48901 agaacctatg ttgcacaata gatattattt accataataa acttttagat atatctcttt
    48961 taattcactc atcaatgggt atctaggatt agcacctgta cattggtcat caaaagcttg
    49021 ttcaaccata gcatccaatc tttctaagaa tttagattct tctactccag cctcttttat
    49081 agtcttagga agacctactt ttgcctttag ttcatctatt gcttttataa gattatctac
    49141 tttttcttgg tctgtacttc ctttaatacc tgcaaaagaa gcaaattcag catatctttg
    49201 tatgcaatca ggatatctgt attgtgagaa tgcacccatt ttatttggag cttctgcaca
    49261 attgaacttg attacttcat ttattaataa tgcatttgca acaccgtgtt gaacatggtg
    49321 gaatgcacct aatttatgtg ctaaagagtg acatattcct aagaaggcat ttgcaaaaga
    49381 cattcctgcc atagtagatg ccattgccat tttttctctt gcttctttat cattctttcc
    49441 atttttatat gcacgaggta aatattcaaa tattatttta cctgcttgta gtgctagacc
    49501 gtcagctggt tcagttctta acatagatac atatgcttct aatgcatgtg ttaaagcatc
    49561 aacacctgat gctgctgtta atcttggtgg catctccatc atcatatcag catcaattat
    49621 agccatgttt ggcattaatt cataatctgc taatgggtac tttacacctg aatcttggtc
    49681 agttataact gcaaatggag ttacttctga accagttcct gctgaagttg ggatagcagc
    49741 aaaatacgct ttttcaccca tcttaggaaa tacatatact ctttttctta tatccataaa
    49801 tctcatagct aagtcttgga aatctacttc tggatgctca tacattaccc acattatctt
    49861 accagcatcc attgcacttc ctccacctac agctattatt aaatctggtt ggaaatcagc
    49921 catagcttta gctccttctc ttgcacaagc taatgttggg tctggagcta catcaaagaa
    49981 tgtagtatgc ttaattccca tctcatctaa taaatcagtt aatttcttag tatatccatt
    50041 attatatagg aaagaatctg ttactataaa tgctttcttt ttatccataa catccttaaa
    50101 ttctcttgct gctacaccta aacatccttt tttgaaataa accttttctg gtgctctgaa
    50161 ccaaagcata ttctctctcc tttcagctac tgtcttgata ttaagcaaat gttttactcc
    50221 aacgttttca gatactgagt ttccacccca agaaccacaa ccaagagtaa gagacggtgc
    50281 caatttaaag ttatataaat cacctatacc accttgtgat gatggagtat taactaatac
    50341 tctacaagtc ttcatagcat ttacaaactt ttctactctc tctggatgat ttatagagtc
    50401 tgcatataat gaagatgtat gaccatagcc tccatctgca actaattttt ctgctttagc
    50461 aactgcatct tcaaaacttt tagacttgta cattgcaagt acaggagaaa gtttttcatg
    50521 tgcaaaaggt tcatttaatt caacagattc tacttcacca attattattc tagctgtttt
    50581 tggaacttct acatccgcca ttttggctat tacatgtgct ggttgtccaa ctattctggc
    50641 atttaatgaa ccatcaatta ttactacttt tcctactttt tcagtttctt ctttatttag
    50701 gaaatgtgct ccacgatatt taaattcttt tttaacttct tcatatattt tttctggtac
    50761 tattacagct tgctcggaag cacatatcat accattatcg aatgattttg atactaagat
    50821 tgaacttaca gccattttta tatctgcact ctcatctatt attgcaggta catttccagg
    50881 cccaactccg acagctggtt tacctgaaga gtatgcagat ttaaccattc caggtccacc
    50941 agtagctaat ataaggtctg cctctgccat gacaacatta gttaattcaa tcgaaggaac
    51001 atctacccaa cctataagtc cttttggtgc tcctgcctta actgctgcat catgtacaac
    51061 tctagctgct tctatagtac agtttttagc tcttggatga ggagagaaaa ttataccatt
    51121 tctagttttt agtgctatta gggatttgaa tattgcagtt gatgtaggat tagttgttgg
    51181 tataactgct gataaaacac ctactggctc agcaattctt gtaaaaccaa atgcttcatc
    51241 tttttctatg acaccacaag ttttagtatc tttataagca ttatagatat attctgaggc
    51301 aaaatggttt tttataacct tatcttcaac aatacccata ccagtctctt ccactgccat
    51361 ttttgctaga ggtattcttt gttgattagc tgcagttgaa gcagctaaga aaatcttatc
    51421 tacctgttct tgcgtaaatg ttgcaaattc tttttgtgcc aatctaattt cttctaatct
    51481 cattcttaat gtttcaacac tgttgacaat ttcaggacta catacttcaa catttgattt
    51541 ttctactacc ttttcttttt tctccatact aaaaacctcc ctaaaataat tatgcatctc
    51601 taatttttat taatcttaaa tgcatcatct atatttttaa cttatactta aaataatttt
    51661 atagatttca tctctatacc ttagatttta tttattttac tctcttaggt caagaagttt
    51721 ttttctgaat attttgtcaa tttatttttt aacaaatata ttattttttt tacttttact
    51781 aaaatttttt atctaaatga gatatatttc atttgaataa tttacttcga ctaaataaaa
    51841 tactaaaatg ataatttata tctttcattt tttttactta ttaaatttta tatgttattt
    51901 gcatgttatt tgtataagta gtaaataaaa tttttgtcgt atttttataa aataacact
//
LOCUS       DAGQVA010000019        51785 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.019, whole genome shotgun sequence.
ACCESSION   DAGQVA010000019 DAGQVA010000000
VERSION     DAGQVA010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.019"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            1..75
                     /locus_tag="MIV85_001298"
     tRNA            1..75
                     /locus_tag="MIV85_001298"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33..35,aa:Thr,seq:tgt)
     gene            90..174
                     /locus_tag="MIV85_001299"
     tRNA            90..174
                     /locus_tag="MIV85_001299"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:124..126,aa:Tyr,seq:gta)
     gene            184..267
                     /locus_tag="MIV85_001300"
     tRNA            184..267
                     /locus_tag="MIV85_001300"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:218..220,aa:Leu,seq:tag)
     gene            292..366
                     /locus_tag="MIV85_001301"
     tRNA            292..366
                     /locus_tag="MIV85_001301"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:324..326,aa:Gly,seq:gcc)
     gene            391..467
                     /locus_tag="MIV85_001302"
     tRNA            391..467
                     /locus_tag="MIV85_001302"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:425..427,aa:Arg,seq:tct)
     gene            477..552
                     /locus_tag="MIV85_001303"
     tRNA            477..552
                     /locus_tag="MIV85_001303"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:510..512,aa:Gln,seq:ttg)
     gene            561..636
                     /locus_tag="MIV85_001304"
     tRNA            561..636
                     /locus_tag="MIV85_001304"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:594..596,aa:Lys,seq:ttt)
     gene            639..727
                     /locus_tag="MIV85_001305"
     tRNA            639..727
                     /locus_tag="MIV85_001305"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:673..675,aa:Ser,seq:tga)
     gene            731..806
                     /locus_tag="MIV85_001306"
     tRNA            731..806
                     /locus_tag="MIV85_001306"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:764..766,aa:Phe,seq:gaa)
     gene            813..886
                     /locus_tag="MIV85_001307"
     tRNA            813..886
                     /locus_tag="MIV85_001307"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:847..849,aa:Met,seq:cat)
     gene            901..977
                     /locus_tag="MIV85_001308"
     tRNA            901..977
                     /locus_tag="MIV85_001308"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:935..937,aa:Ile,seq:cat)
     gene            995..1071
                     /locus_tag="MIV85_001309"
     tRNA            995..1071
                     /locus_tag="MIV85_001309"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1029..1031,aa:His,seq:gtg)
     gene            1080..1155
                     /locus_tag="MIV85_001310"
     tRNA            1080..1155
                     /locus_tag="MIV85_001310"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1113..1115,aa:Lys,seq:ttt)
     gene            1163..1236
                     /locus_tag="MIV85_001311"
     tRNA            1163..1236
                     /locus_tag="MIV85_001311"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1195..1197,aa:Cys,seq:gca)
     gene            1243..1319
                     /locus_tag="MIV85_001312"
     tRNA            1243..1319
                     /locus_tag="MIV85_001312"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1277..1279,aa:Arg,seq:acg)
     gene            1332..1407
                     /locus_tag="MIV85_001313"
     tRNA            1332..1407
                     /locus_tag="MIV85_001313"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1365..1367,aa:Val,seq:tac)
     gene            1483..1896
                     /locus_tag="MIV85_001314"
     CDS             1483..1896
                     /locus_tag="MIV85_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960663.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSTFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2205..5636
                     /locus_tag="MIV85_001315"
     CDS             2205..5636
                     /locus_tag="MIV85_001315"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBY2960664.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLLAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5878..7806
                     /locus_tag="MIV85_001316"
     CDS             5878..7806
                     /locus_tag="MIV85_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBY2960665.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAITPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8263..8727
                     /locus_tag="MIV85_001317"
     CDS             8263..8727
                     /locus_tag="MIV85_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBY2960666.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8734..9228
                     /locus_tag="MIV85_001318"
     CDS             8734..9228
                     /locus_tag="MIV85_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBY2960667.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9244..10269
                     /locus_tag="MIV85_001319"
     CDS             9244..10269
                     /locus_tag="MIV85_001319"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBY2960668.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLKAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10256..12703
                     /locus_tag="MIV85_001320"
     CDS             10256..12703
                     /locus_tag="MIV85_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBY2960669.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12883..14256
                     /gene="radA"
                     /locus_tag="MIV85_001321"
     CDS             12883..14256
                     /gene="radA"
                     /locus_tag="MIV85_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBY2960670.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSEKLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14259..15329
                     /gene="disA"
                     /locus_tag="MIV85_001322"
     CDS             14259..15329
                     /gene="disA"
                     /locus_tag="MIV85_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBY2960671.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAITNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15418..16512
                     /locus_tag="MIV85_001323"
     CDS             15418..16512
                     /locus_tag="MIV85_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBY2960672.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16641..18818
                     /locus_tag="MIV85_001324"
     CDS             16641..18818
                     /locus_tag="MIV85_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960673.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKIIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVVFVELGDTYRLDLYKPNLNEKTYESMKANIEKNIDVYLKNIFSMVGEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGITIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNMPKWSVIVFSLLILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGAGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19004..19849)
                     /locus_tag="MIV85_001325"
     CDS             complement(19004..19849)
                     /locus_tag="MIV85_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2960674.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            20066..21232
                     /locus_tag="MIV85_001326"
     CDS             20066..21232
                     /locus_tag="MIV85_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBY2960675.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLTEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            21254..22900
                     /locus_tag="MIV85_001327"
     CDS             21254..22900
                     /locus_tag="MIV85_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBY2960676.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNTESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            22997..24370
                     /locus_tag="MIV85_001328"
     CDS             22997..24370
                     /locus_tag="MIV85_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2960677.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNYIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            24815..25768
                     /locus_tag="MIV85_001329"
     CDS             24815..25768
                     /locus_tag="MIV85_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBY2960678.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25806..26768
                     /locus_tag="MIV85_001330"
     CDS             25806..26768
                     /locus_tag="MIV85_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBY2960679.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26793..27779
                     /locus_tag="MIV85_001331"
     CDS             26793..27779
                     /locus_tag="MIV85_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBY2960680.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEVAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27792..28838
                     /locus_tag="MIV85_001332"
     CDS             27792..28838
                     /locus_tag="MIV85_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBY2960681.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETILGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29005..30735
                     /gene="lpdA"
                     /locus_tag="MIV85_001333"
     CDS             29005..30735
                     /gene="lpdA"
                     /locus_tag="MIV85_001333"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBY2960682.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDTV
                     KENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSMPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            31153..34101
                     /locus_tag="MIV85_001334"
     CDS             31153..34101
                     /locus_tag="MIV85_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2960683.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEVISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            34079..34543
                     /locus_tag="MIV85_001335"
     CDS             34079..34543
                     /locus_tag="MIV85_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2960684.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            34623..34925
                     /locus_tag="MIV85_001336"
     CDS             34623..34925
                     /locus_tag="MIV85_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2960685.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            34987..36351
                     /locus_tag="MIV85_001337"
     CDS             34987..36351
                     /locus_tag="MIV85_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBY2960686.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            36386..36859
                     /locus_tag="MIV85_001338"
     CDS             36386..36859
                     /locus_tag="MIV85_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960687.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            37031..37681
                     /locus_tag="MIV85_001339"
     CDS             37031..37681
                     /locus_tag="MIV85_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBY2960688.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTASDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            37855..38787
                     /locus_tag="MIV85_001340"
     CDS             37855..38787
                     /locus_tag="MIV85_001340"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBY2960689.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            39061..39774
                     /gene="ispD"
                     /locus_tag="MIV85_001341"
     CDS             39061..39774
                     /gene="ispD"
                     /locus_tag="MIV85_001341"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBY2960690.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVKETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            39771..40256
                     /locus_tag="MIV85_001342"
     CDS             39771..40256
                     /locus_tag="MIV85_001342"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBY2960691.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    40351..40559
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            40623..42338
                     /locus_tag="MIV85_001343"
     CDS             40623..42338
                     /locus_tag="MIV85_001343"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBY2960692.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            42460..43905
                     /locus_tag="MIV85_001344"
     CDS             42460..43905
                     /locus_tag="MIV85_001344"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBY2960693.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            44343..45824
                     /locus_tag="MIV85_001345"
     CDS             44343..45824
                     /locus_tag="MIV85_001345"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBY2960694.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            46045..46200
                     /locus_tag="MIV85_001346"
     CDS             46045..46200
                     /locus_tag="MIV85_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960695.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            46345..47742
                     /locus_tag="MIV85_001347"
     CDS             46345..47742
                     /locus_tag="MIV85_001347"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBY2960696.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHSQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            47727..48140
                     /locus_tag="MIV85_001348"
     CDS             47727..48140
                     /locus_tag="MIV85_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBY2960697.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            48246..49004
                     /locus_tag="MIV85_001349"
     CDS             48246..49004
                     /locus_tag="MIV85_001349"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBY2960698.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEVLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            49017..49754
                     /gene="rlmB"
                     /locus_tag="MIV85_001350"
     CDS             49017..49754
                     /gene="rlmB"
                     /locus_tag="MIV85_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBY2960699.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            49757..50284
                     /locus_tag="MIV85_001351"
     CDS             49757..50284
                     /locus_tag="MIV85_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBY2960700.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            50349..50996
                     /gene="sigH"
                     /locus_tag="MIV85_001352"
     CDS             50349..50996
                     /gene="sigH"
                     /locus_tag="MIV85_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBY2960701.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            51070..>51785
                     /locus_tag="MIV85_001353"
     CDS             51070..>51785
                     /locus_tag="MIV85_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBY2960702.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVE
                     DVFSITGRGTVATGRVERGVL"
BASE COUNT        21070 a         5588 c         9832 g        15295 t
ORIGIN      
        1 gctggtgtgg ctcaacggta gagcagctga cttgtaatca gcaggttgta ggttcgattc
       61 ctatcaccag ctccatgtaa aattaatacg gaggatttcc cgagcggcca aagggggcag
      121 actgtaaatc tgttgtcatc gacttcggtg gttcgaatcc accatcctcc accaaaaaaa
      181 tgcgcggatg tggcggaatt ggcagacgca ctagacttag gatctagcgc cattggcgtg
      241 ggggttcgac tcccttcatc cgcaccattt ttatttaatt ttaataaacg agcgggaata
      301 gttcagtggt agagcgcaac cttgccaagg ttgaagtcgc gagttcgaat ctcgtttccc
      361 gctccaaatt ttgtgtttat attgtaatgt gggtgcatag ctcagctgga tagagcaacg
      421 cccttctaag gcgtgtgtcc ggggttcgaa tccctgtgcg ctcaccacat atatattggg
      481 gattagccaa gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg
      541 catccccagc caaatagtat ggtctattag ctcagtcggt agagcacctg acttttaatc
      601 agggtgtccc gcgttcgagt cgcggataga tcaccaatgg agaggtgtcc gagtggttta
      661 aggagctggt cttgaaaacc agtgacttcg aaaggggccg tgggttcgaa tcccaccctc
      721 tccgccaaat gcccagatag ctcagtcggt agagcagggg actgaaaatc cccgtgtcgg
      781 tggttcgatt ccgcctctgg gcaccaaaat gtggcggtat agcttagttg gctagagcgt
      841 tcggttcata cccgaaaggt cataggttcg actcctatta ccgctactaa aatttaatgt
      901 gggccattag ctcagttggt tagagcgccc ggctcataac cggtaggtct ggggttcgag
      961 tccctgatgg cccaccacat taaattaact tatggtgggt atagctcagt tggttagagc
     1021 gccagattgt ggctctggag gtcgtgagtt cgactctcat tatccacccc aaattatatg
     1081 gtctattagc tcagtcggta gagcacctga cttttaatca gggtgtcccg cgttcgagtc
     1141 gcggatagat caccaaaaag gcggcgacat agccaagtgg taaggcagtg gactgcaact
     1201 ccttgatccc cagttcgaat ctgggtgtcg cctccaataa atgcgctcat agctcaactg
     1261 gatagagtgt ctgactacga atcagaaggt taggggttcg agtccctttg ggcgcaccat
     1321 ataaatagcg agggattata gctcagctgg gagagcacct gccttacaag cagggggtca
     1381 caggttcgag ccctgttaat cccaccagtg caaacctcta gtaaaactac tagaggtttt
     1441 atttttgatt gaaaaagttt ttatatttag gaggtaagaa acttgtatat agtaatagga
     1501 aatgaaatag ttgatagtga agaacttaaa ataattatag ataaaaatag tacatttaaa
     1561 gttgaaaaag atttaagtaa aagcacaaaa agagaagatg taatagcata tcagttaagt
     1621 atagatttaa attacttaga ttctcttata aatgagcaat gtaatttagc cagtctatct
     1681 gatgaagaga aatttgatga atatatgact ttatctgatg aacttgcact ggatttagaa
     1741 gagctaatgc caaaatatac aataataaat gctagagcat ataaattaga cgaggtagat
     1801 ggaattgtaa aaataatact agctgtagcg tatgcagatt tagggcactt aaaactttct
     1861 gatgtagtaa agaggctatc tagacaagta gattaggata tgaatatgaa ctatattaaa
     1921 aaaatgtata aaatcttacg taaagatgaa aataattatg taaacataga aaaaaacagt
     1981 ataaaatcaa gtcaattgta ggaattttca cataaattca tctgaaattc tataaaaaat
     2041 gccttaattt taatgaggta aatcgagttt acacagtcta aaaattactt atatttataa
     2101 atttatctta ttaattaagg aactttctta aacatcttca aaaataaagt attttagtct
     2161 ataatcttta atattacaca aacaataaag gagaagaata gagtatgctt aaaaagttta
     2221 ataaaatact agtggctaat agaggcgaaa tagctataag aatatttaga gcctgttcag
     2281 aattggggat aaaaagtgtt ggtatataca gtaaggaaga taaatatgga ttgtttagaa
     2341 caaaagcaga tgaatcatat ttgataggag aaggtaaagg gccaatagat gcatatttag
     2401 atatggatgg aataatagac ctagcaaaga gaaaaaaagt tgatgctata catccaggat
     2461 atggttttct agcggagaat gcagaatttg ctcgtaaatg tgaagagaat ggaattactt
     2521 ttataggacc atcatctaag gtaatgaata tgatggggga taagattaac tctaaaaaaa
     2581 tcgcaaaaga agttaatgtt caaactatac caggagtaga aaaagcaata agaagtactg
     2641 aagaagcaaa ggaagttgca aacaaaatag gctatcctgt tatgataaaa gcatctaatg
     2701 gtggtggcgg tagaggtatg agaattgtac atcgcgaaga agacttagag cttgaatatg
     2761 aaactgcttg tagtgaatca agaaaagctt ttggagaaga tattatattt atagaaaaat
     2821 atatagctga tccaaaacat atagaagttc aaatattagg agataactat ggaaatatag
     2881 ttcacttata tgaaagagat tgttctgttc aaagaagaca tcaaaaaata atagaatatg
     2941 caccagcttt ttcgttagat gataaagtaa gaaaagagat atgtgaagat gcagttaagt
     3001 tatcaaaaca tgtgggttat tctaatgcag gaacattaga atttttagta gatgcaaatg
     3061 gtgggcatta ttttatagag atgaacacaa gagtacaggt tgaacatact gtaacagaga
     3121 tggttacagg aatagatata gtgcaaagtc aaatactaat agcccaaggt tacagtttag
     3181 atagtgaaga aattaatata aaatcacaag atgatgtgga aataagaggt tactctatcc
     3241 aatgtagaat aactacagaa gaccctaaga ataaattcat gcctgataca ggtaaaattc
     3301 aagtttatag aactggttca ggatttggta taagactaga cggaggaaat ggatttacag
     3361 gggcaaacat aagtcctcac tatgatagtt tattggttaa gacaatatct tgggatagaa
     3421 cattccaagg agcaataaat aaaactataa gatctataaa agaacttaga gttagaggtg
     3481 ttaaaactaa tgtaggattc ctagttaatg ttttaaataa tcctatattc tcaaatggta
     3541 aatgtagtac taagtttata gatgaaaatc cagatttatt tgaaataaca gaaagtaaag
     3601 acagaggaac aaaattactt caatttatag gagatgtaat tgtaaatgat aatgcttgta
     3661 aagaaaaacc attatttgat gcattacatg acccaagaat ggataaggat ggctcaaaat
     3721 cagaaggaag taaaatactt ttcgataagt taggtaaatc tgcatatata gaaaagataa
     3781 aaaatgataa gaaattatta ttaacagata caacaatgag agatgcacat caatcattat
     3841 tagcaacaag aataagaaca tatgacttat taaaagctgc taagccaaca gaaaaatatc
     3901 aaaaggattt attctcactt gaaatgtggg gaggagctac ttatgatgtt gcatatagat
     3961 tcttaaaaga atctccttgg cgtagattac aaaagctaag agaagaaata ccaagcataa
     4021 tgttccaaat gttgcttaga gcatcaaatg gagttggata taaaaactat ccagataatg
     4081 taatagaaga atttacaaaa gaatctgcta gacaaggtat agatgtattt agaatatttg
     4141 attcattaaa ctgggttgaa aatatgaagc catctattaa tacagcttta gaaactggaa
     4201 aaattgttga agcaactatg tgttatacag gtgatatact agataagact aaaactaaat
     4261 acaatctaga atattatatt aaaatggcac aagaattaga aagcttggga gcagatataa
     4321 tagcaataaa agatatgtca ggtcttctta aaccatattc agcttacaca ctagttaaag
     4381 agttaaagaa aaatgtaaaa gcaccaatac atttacacac tcatgataca agtggaaatg
     4441 gtgtagcaac ttgtttaatg gcatcagaag ctggagtaga cataattgat gctgcattag
     4501 aatctatggc aggacttaca agtcagccat cacttaatgc tatagtagag gcacttaaaa
     4561 atacagagag agatacaggt atagatttat ttggatatga tgagttagga aaatattata
     4621 aggatttaag aaaagtttat aataaatttg aaagtgattt aactaattct tgtgcagaaa
     4681 tatataattt tgaaatacca ggaggccaat atacaaactt aaaacctcaa gctgatagtt
     4741 taggattagt taatagattt gatgaagtta aagaaaaata taaagaagct aatgaagttg
     4801 taggagatat aataaaagta actccatctt caaaagttgt aggagattta gctatcttta
     4861 tgactaaaaa taaattagat aaagacaata taatagaaga aggtaaaaat ttatcattcc
     4921 cagattctgt tgtggattac tgtaaaggta tgattggtca accagaaggt ggaataccaa
     4981 aagatttaca agaggtagtt ctaaaaggtg aagaagctat aacagtaaga ccaggttcat
     5041 tattactagc agaagatttt gatgaaatag ctaaatatct aaatgaaaaa tatgatataa
     5101 atgctaatat aagaaatgtt ataagttatg ctttatatcc aaaagtatat gaagattata
     5161 tcaaacattt acaacattac aatgatatat ctaaacttga aagtgatgta ttcttctatg
     5221 gattaaataa aaatgaagaa tgtgaagtag aaatagaaga aggtaaggta ttaacaataa
     5281 gattagttga aatcggtgaa gttaaggaaa atggatttag aactatagga tttgagttaa
     5341 atggaatggt tagagaagta gaaataaaag ataagaattt ctctggaaaa attaataatg
     5401 ttgaaaaagc tgatatgaat gaccctcttc aaattggagc aagcatacca ggaaaagtta
     5461 taaaaataat ggttaaagaa gaagatgaag taaaagcaaa tcaaccatta atcgtcatag
     5521 aggctatgaa gatggaaact ataatagttg ctaagactga tggagtaatt aagtcaatca
     5581 aagtaaaaga agatgatatg gttgaagata aacaattatt aatgataatg aagtaattga
     5641 attaaaataa attaaaaagc actctgaaat gtttaataaa aaatgtttta gagtgttttt
     5701 atttatttta attaaatatt tgttaaaaaa aagaggacaa tcacctccag atgtagaaat
     5761 aaagctagta aggaaaatgt tatctaaaaa ttctaaatat agtaaatatt ttccataata
     5821 tttcttagga aataacagca aagataaaat acataaattt aaaaggtggg tgcttatatg
     5881 aaggtttatg atagtaaaat gttgagaaat gtagcggtat taggacatag cggatgtgga
     5941 aaaacaaatc taatcgaaac tatagcttac acagcaaaca ctaataagat acctaaatta
     6001 acagacaagg taaatatgac ttatagcatg ggattaatac ctatagagta taatgattat
     6061 aagtttaact tattggatac cccaggatat tttgacttta gcggagacgt tgtgtcatct
     6121 cttagagcaa gtgatgcggc aataatagta atagatgcaa cagcgcctat tcaagttggt
     6181 acagagaaat cattagaact aactgagagt attcctaaga taatgtttat aaataaaata
     6241 gataatgaaa aggcaagata caaagatgca atagcaatgt taagagaaaa atacaataat
     6301 aagatagttc ctatgataag tcctatatac aaagataaaa actttgtaaa gttacataat
     6361 gtttttgaaa acatagatga tttagaaggt gaatttaagg aacaagctat gagtgttaaa
     6421 gaagcattaa tggaacttat agcagaaact gatgaccaaa tattagataa atattttaat
     6481 ggagaagaac taactacgga agagatacaa aaaggtatta ttataggtat acaaagaggt
     6541 gatattatac ctgtaatatg tggttcaact ataaataata taggcacaaa agaaatatta
     6601 gatacaatat caagttattt agaacctatc tttacagagg aaagcaaacc atttagggga
     6661 ttagtattta aaactatggt tgacccattt gttggaaaga tgtcatatat aaaaattact
     6721 gagggtgtac tttctaagga taaagatgtt tttaatataa ataaaaatgt aaaagaaaaa
     6781 atagctaata tatatacatt gagaaatagt gaattagtag aaatagaaaa agctaaagct
     6841 ggtgatatag tagttataac taaagtcaat tctctaaaaa caggagacac tatatctgca
     6901 gataaagatg cagaagcttt agaaaagata gattttccta aaccacaaat atattatgca
     6961 ataactccta agaataaagg tgatgaagaa aaagtagcat ctgtattaaa taaactagta
     7021 gaagaggacc ctacattaca ttggtataga aatacagaga caaaacaagc acttttagga
     7081 ggtcaaggag aacttcatat aaaaacaatt aaaaataaaa tgaaagataa gtttggtgtt
     7141 gatgttgaat tgaatgacct taaagttcct tatagagaaa ctataaaagg aacagctgat
     7201 gtacaaggaa aacataaaaa gcaatcaggt ggtcatggtc aatatggaga cgtaaaaata
     7261 agatttgaaa gatgtgaatc tgattttgaa tttacagaag aaatatttgg tggttctgta
     7321 ccaaaacaat atataccagc agttgaaaaa ggtctaaaag actctatgca aaaaggtata
     7381 ttagcaggtt atcctgttac aaacataaaa gctacgcttt atgatggttc ataccatgat
     7441 gtagactctt ctgaaatggc ctttaagatg gcagcaagtg cagcctttaa aaaaggcatg
     7501 gaagaagcgc acccaatact actagaacct ataatgaaac ttaagataac tgttccagaa
     7561 gaatatatgg gagatgttat gggtgatata aataagagaa gaggaaaaat atttggaatg
     7621 gaaccagatg acaaagggaa acaaataata tttgcagaag ctccacaggc agagacattt
     7681 aaatatgcaa tagatttaag agcaatgaca caaggtagag gatactttga aatggaatta
     7741 gagagatatg gagaggttcc atcacagttt gcagaaaaaa taattgggtt agctactgca
     7801 aagtaatgaa caaaataaat agaataataa ataattaata gatactatta aaaatatttt
     7861 tagggtttta actaggtata agtttatgtt agataaactt atacctagtt tttatatatt
     7921 tttgatggat aaaaaaatat ataatacttt cttaaacgtt ttaataaaaa gaaagtattt
     7981 ttttattatt atctttacaa atgtttagca ataaagatga gaaggtatat ttaaaatata
     8041 aagtatttaa agttctgaaa tctaatcata aagcaaaaaa ttagcatttg gttatcaata
     8101 aatataataa ataaaaactc ataattaatg aaagaataaa tccatatcta aatttctata
     8161 aaaaatttaa atttatacaa tttagggctt taaaaattta aataataggt gtaaaataat
     8221 agtcaaagaa agtcaaaaat aaaaaggtgt gtggtgatat taatggcaac tatgacagat
     8281 ataattgaaa aatttattaa agatttgatg gaagaagata atagcataca aattcaaaga
     8341 aatgaactag caaacttgtt tagttgtgca ccatcacaaa taaattatgt cttaacaaca
     8401 agatttacaa tagatagagg atattacatt gaaagtaaaa aaggtggcgg aggatatgtt
     8461 caaatagaaa aaatacgaaa aagtaaagat ggacatatta gagaactact aaatgaaaaa
     8521 ataggaagtc agatatccta taaaaaagca aaggaattat tagaaggttt aaaagagtcg
     8581 gatttgatta acgaaagaga attaaaatta atattatatg caatagatga taaatcattg
     8641 tgtatgccaa tatatgaatt aaaagagaag gtaaggtcta atattttaaa gaatataata
     8701 ataggattat ttagtataga ggagtgataa tttatgctat gtcaaaaatg caataagaat
     8761 aaagcatctg tatattataa taagatagtc aatggagaaa aaacagagat gtatttatgt
     8821 agtgagtgcg caaaagagaa tacagaaatg aattttaatt tagatatgcc tttttcaatg
     8881 atggatatat tttccaattt aggttttcaa cctaaaaaag aacttgagga aaagctagtt
     8941 tgtcctaaat gtaatacaac atatagtgag tttaagaata atggaagatt tggatgtagt
     9001 gaatgttata atgcatttag tagtcaagta aatccaatgc ttcaaaatat acatgggcat
     9061 atagaacata caggaaaagc acctaaaaaa tctttttata agataagtgt agaaaatgag
     9121 attaaagaac taaaagaaga tttagataga gctataaaaa atgaagagta tgaattagca
     9181 gctcaattta gagataaaat taaatattta aaaggttcta ttgactaaga ttggagtgat
     9241 attatgaaag agaacatagt catgaaatca agagttaggc tagctagaaa tttaaataac
     9301 tatccctttc caaataaatt agataaagaa tgtgccatgg aaataataga aaaagtaaaa
     9361 aatgcgttta ttaattctaa cttagaacaa aaagaagaat ttgatttcta taaaattgaa
     9421 gatttagacc aatctaaaaa aatgcttatg gttgaagaac atataataag cccagattta
     9481 gcagaaaatg ataaaagtgc agttatagta aaaaaagata aaactataag cataatgata
     9541 aatgaagaag accatataag gatacaaact atatgtgatg acttaaactt agaatatgca
     9601 tatagtgtag caaatgaaat agatgatttg ttagaatcaa gtttagaata tgcatttaac
     9661 acaaagctag gttatctaac atcttgtcca actaacacag gaacaggaat gagagcttct
     9721 gtaatgatgc atttaccagc attaagtcag ctaggttata tggatgaact ttataaaatt
     9781 tcatcacaaa taggtatagc aattagaggg atatatggag aacgaacaga agcattagga
     9841 aatatatatc aaatatctaa tcaacttaca cttggaagaa cagagtctaa tattatagaa
     9901 aatgtaagtg gacttacaaa agatgcaatt tcaaaagaaa taaaagctag agaaatattg
     9961 caaaaaaaat taggtataaa actagaagat aaaatattta gatcgatagg gacacttgaa
    10021 aattcaagag taatgagtag cgcagaggca atgagccatc tatcaaatat aaaaatggga
    10081 atagaaatga actatataga taaactagat ttaaaggcta tagaacaact tatgataggt
    10141 atacaaccag cacatcagtc aataatgtat aagagtgatg atgttgagaa tagagatata
    10201 aatagagcaa catatattag agaaactttg gaaaaattaa gaggagggat gaattgtgaa
    10261 cttcaataga tttacacaaa gagctaaaaa ggcaattgat ttagcgtttg aatctgctaa
    10321 aagtttagga cacaatattg tcggaagtga acatatactt ttaggtcttt taagagaaga
    10381 agaaggtata gccgctaaag ttctaagtaa agttggattt acagaagctt atttagaagg
    10441 caaaatagtt gatatggaag gtaagggaga agaaatctca gaagacatag tattaagtcc
    10501 aaggagtaaa caaatacttg aattatcagg tatgtttgca aataaattaa aaacaaatta
    10561 tattgggact gagcatatat tattagcaat tattcaagaa ggtgaaggaa tagctaataa
    10621 gattttaaat tatgctggag taaatgatag gactttagcc caattaacaa ttgatatgat
    10681 gggtattagt gataaaaatc aatacaaagc agaaaatagt tacacgggca accagaatca
    10741 agcagaatct aaagtacttg ataagtatgg aagaaatctt acactatatg caaaacagaa
    10801 taaaatagac cctgtaatag gtagagaaaa agaaatacaa agagtaatac aaatattaag
    10861 tagaagaact aaaaacaatc cagtgttgat aggagaccca ggcgtaggga aaacagccat
    10921 agctgaaggt ctggctacaa atatagcctt aggaaatgtt ccagaaacac taaaaaacaa
    10981 aactttatac tctttagaga tgggttcatt attggctggg gctaagtata ggggagaatt
    11041 tgaagaaaga attaaagaag ttgtagatga agttgttaaa aatggaaaca taatcttatt
    11101 tatagatgag atgcatacta taataggggc tgggtctact ggagaaggct ctatagatgc
    11161 ttcaaatata ttaaagccag ccttagcaag aggagaaata caagttatag gtgcaactac
    11221 aattgatgaa tatagaaagc atgttgaaaa agattctgct ctagaaagaa gattccaacc
    11281 agttatggta gatgaaccaa ctaaagagga ttcaataaaa atattagaag gattaagaga
    11341 taaatatgaa gctcatcata aagttaaaat aactgatgat gctataaagg cagctgtaga
    11401 attatcaact agatatatat cagacagata tcttccagat aaagcaatag acttaattga
    11461 tgaagctgca tcaaaagtaa gattaaaaga aaatacacct ccttcagaaa taaaaaaatt
    11521 agaactagaa atagaaaata tagataaaga aaaagaagaa gcagtaagat gtcaagactt
    11581 tgagaaagca gccaaaataa gagatgaaca aggtctactt aaaaaacaat tagaagatgt
    11641 tagagaaaga tggaacaagt catctaaaca ttcagattta gttgatggag aagttattgc
    11701 tgaagtagtg ggcttatgga caggaatacc agttaataaa attcttgaag aagaggctga
    11761 tagacttttg agacttgagg aaatactgca caatagagtt ataggtcaag aacaagcagt
    11821 aaaatctatc tcaaaggcaa tcagaaggtc aagagcaggt cttaaagacc ctaatagacc
    11881 aattggttca tttttatttt taggtccaac aggagtaggt aaaacagagt tatctaaggc
    11941 attagcagaa gtacaatttg gagatgaaaa tcaaataatt agaatagata tgtctgaata
    12001 tatggaaaaa catgctgtgt caagaatgat aggttcacct ccaggttatg taggtcatga
    12061 tgaaggtggt caattaactg aaaaagtaag aagaaatcca tattcagtta tattatttga
    12121 tgagatagaa aaagctcatc cagatgtatt taatattctg ttacaaattc tagatgatgg
    12181 tagactaact gattcaaaag gaagaactgt agattttaag aatactattg taataatgac
    12241 atcaaacgtt ggagcatcta caattggtag acaaaaaact ttaggattta gtatagctaa
    12301 aggagacgaa gaagaaaaat ctcaatatga aaaaatgaaa gaaaatataa tgggtgaatt
    12361 aaaacaaaga ttcagaccag agtttttaaa cagaatagat gatataattg ttttccactc
    12421 attaaatgaa aatcatatat caaaaatagt acttttaatg gcagcgaaac tacaagagag
    12481 attaaaagaa atggatataa aattagaaat gagtgatgag gctgttaaat taatttctaa
    12541 atctggattt gacttagaat atggagcaag acctcttaaa agagctttac aaaaagagtt
    12601 ggaagatgag ctatctgaag caatcttaaa aggtaatgtg aaaaagggaa gtaatgtagt
    12661 agcaaaagta aaagatgaaa aaatagtttt tgaaactaaa taatttaata gagttgcatt
    12721 ttaaaatatt gcaaatataa gttttataat ctaaacaaaa ttttaagggc aatgaatcta
    12781 taataattca ttgtccttaa ttattttatt taatctttac atattgtctt tcagatatgc
    12841 taaaattata gtatagaata aaaaattaag gatgataaaa gtatggcaaa aataaaaaca
    12901 aaatatgtat gtcaatcttg tggatatgaa acagctaagt ggcttggtaa atgtccagaa
    12961 tgtacaaaat ggaatacatt tgtagaagaa atagaccaaa aaagcaccaa aaaagaggtc
    13021 tttataatag ataaatcttc atctaaacca gtcagtataa actcaataga aagtaaagaa
    13081 gaagagaggt ttacaacaga tataaacgaa ttagatagag tgcttggagg aggtatagtt
    13141 aaaggctctt tagtgcttgt tggtggtgac cctggtatag gtaaatcaac acttttaatc
    13201 caagtatcta gtaatgttgc caatttagga aaaactgttt tatatataac tggagaagaa
    13261 tcagaatctc aaataaaaat gagagctaaa agattaggta ttaactcaga aaaattatat
    13321 atatttgctg aaaataattt aagtataatt gaatcttatt tagaaagtgt aaatccagaa
    13381 ttaataattc tagactcaat tcaaactgtc ttcagtccag aaatatcctc ggcaccagga
    13441 actgtcagcc aaattaaaga aggtacttca aaattcatga aaatttctaa aaaaatggga
    13501 atttcaacgt tcatagttgg gcatgttaca aaagaaggtt cactagcagg accaaaatta
    13561 ttagagcata tggttgatac tgttctatat tttgaaggag aaagatataa tacttataga
    13621 ttagtgagag ctgttaaaaa tcgatttggc tcaactaatg aacttggagt atttgaaatg
    13681 agggatttag gattagtaga acttgacaat ccatctaaaa ttttaatctc tgaaaaacca
    13741 aaagatgtag caggttcagt aataatatct actgtagaag gtacgagacc aatgttactt
    13801 gaattgcaag cattagtttc tcctacaagt tttggtatac caaaaagaac atctacagga
    13861 gtcgattaca atagagtagg tatgttatta gcagtattag aaaaacgtgt tggtttgcaa
    13921 atacaaaatc aagatgtcta tataaacata gttggaggaa taaagataaa tgaaccttca
    13981 attgatttag ggatagccat ttctgtagca tctagtttta gaaatatacc gatagatgaa
    14041 gatatagctg tcacaggaga agttggactt acaggagaag tcagagcagt aagctttata
    14101 gaaaagagaa tagctgagtg taaaaaactt ggatttaaaa agatagtagt tcctagaagt
    14161 aattatgatg ttgtaaaaga gaccaaaggc atagaaatat ggccagtgga taacttaaga
    14221 caagctataa atatagtact tgggaggaat caataaatat ggagaatttt ctagataata
    14281 aaaatatgct atatgcatta aaaatgatat ctcctggaac tccacttaga ttaggtttaa
    14341 acaatgtact aagagctaag actggtggac taattgtaat tgcaacaaac gaagatgtaa
    14401 tgaaaatagt agatggagga tttgctataa atgcagaata ttcaccatca tatctatatg
    14461 aattagctaa aatggatgga gctatagttt taagtggtga tgtaaagaaa atattatttg
    14521 ctaatgcaca acttatacct gactatttta tagaaacatc agagacggga acaagacata
    14581 gaacagcaga aagagtagca aaacaaactg gtgctatagt cataggaatt tcacaaagaa
    14641 gaaatgttat aacagtttat agaggaaatg agaagtatgt agtcgaagat atatctaaga
    14701 tatttactaa ggcaaatcag gctatacaaa ctctggaaaa atataagaca gtattggacc
    14761 aagctataac aaatttaaat gccttagagt ttaatgattt ggtaactatt tatgatgttg
    14821 cattagtcat gcaaaagatg gaaatggtaa tgagagttac aagtataatt gaaaaatatg
    14881 tgatagaatt gggtgatgaa ggaactttag taagtatgca attagaagaa ttaatgggta
    14941 caaccagaat agaccagaaa ttaatattca aagattataa taaagaaaac acagaaataa
    15001 aagaacttat gaaaaaggtc aaaaatttaa attcagaaga actaatagaa ttggtcaata
    15061 tggcaaaact attagggtat agtggttttt cagaaagtat ggatatgcct ataaaaacaa
    15121 gaggttatag gattcttagt aaaatacata gactaccaac agccataata gaaaacttag
    15181 taaattattt tgaaaacttt caacaaattt tagatgcatc tattgaagaa ttagatgagg
    15241 ttgaaggaat aggtgaaata agagcaacat atataaaaaa tggactcata aaaatgaaac
    15301 aattagtctt attagataga cacatatgat gaattttaaa tgaattttac tacttttttc
    15361 ttgaatataa tatacacttt ggtctataat agataagtat aactaggggg tgaagcattg
    15421 ataaggaaag taacaagaat attgtttatt ttacttggat ttacaatagg tataacaacc
    15481 tatttaacat taatgaaaga ttttgaaata ttaacatttg gaaaagaaac atatggttat
    15541 atcgcagctg tagtagcagg tataataata gccattttag gatatcttat agaaccatgg
    15601 gttgtaaata aagtaaaaga aattgctaaa atagtggata aagaattgtc aaaatatcct
    15661 cagactgata tattgttagg gtctatgggt cttatagtag gatttgttat tgcgtattta
    15721 ttaagtggat tagtaaatag aataccaata gtaggtggaa tactatcctt actattatat
    15781 ttattcctag gatatcttgg aatgaaagtt gcgcttaaaa gtaaaaatga tttatttaat
    15841 attggaaaac taggaagatt agcaaatcct attaaggata aagataagga taaagaaaat
    15901 aaaaaagaag taaaagccat tcctccaaaa gtattagata caagtgtaat aattgatgga
    15961 agaatagctg atatttgtaa gactgggttt atagaaggaa aacttattat tcctgctttt
    16021 gttttggagg aactaagaca tattgcagat tcttcagatg atttaaaaag agtaagaggt
    16081 agaagaggtc tggatatatt aaatataatt cagaaagaat taaatataga agttgaaata
    16141 agtgagagag actttgatga tatagcagaa gttgatagta aattattaaa gcttgctcag
    16201 gttttaaatg gaaaagttgt tacaaatgat tataacttaa ataaagttgc tcaattccaa
    16261 ggtgttgaag tattaaatat aaatgagtta gctaatgcta taaaaccagt tgctatacca
    16321 ggtgaagata tggttgttca agtggttaaa gaaggaaaag aggctcaaca aggtgttgca
    16381 tatctagatg atggaactat gatagttgtt gatggaggaa gaaaatatat gaatgagact
    16441 ataaaagtac tcgttacttc tgttcttcaa actcctgcag gtagaatgat atttgcaaaa
    16501 cctaaaaatt aatatgttca aagaaaccta taatttgggc tgtttatttt aaatagatgg
    16561 tccaaattta tttatttata acgataatgt ttaatgtatt cttaaagatg gggatttaaa
    16621 tcagaaagca gggagaattt atgagaaaaa agattatatc tttcttagca acatttatca
    16681 taatattaac atcagcaagt cagtatagtt ttgcagatga tatatcaaca cgtggaaaaa
    16741 taatatttat agatatgaat agaactagta tgagtaatat gttaagaata aaatcattaa
    16801 gagaagaact agacaataga gggtatattg gcttgatgaa tataagaggc gataaaggaa
    16861 gtgatgatag aaggtcatat gctagtatgg gtgctggtgg tagagctaat gtggctaatg
    16921 aagaagatat taattttgaa agctcgagta aggatagaaa tatagttttt gaatcagcta
    16981 caggaaaaag tgcaaaaggt ataaataatt taactataaa taagtctata aatgaaaatt
    17041 taaactttgg agagtatggt tctgtattag ggtcattagg acaaagttta tctgataatg
    17101 gattaaaagc atctgtattg ggaaattcag atataattga aaatggccaa cttataaaaa
    17161 acagaaactt atgtctaact gctatggatg aatatggaag aatacctaat ggaaatgtag
    17221 atactataaa taaaaaagac ttatctatgc cttatggaat atcaactgat tatgataaat
    17281 tgattgtaga gaccaaagaa gcttacaaaa ataatgatgt ggtttttgtg gagcttggag
    17341 atacatatag attagattta tataaaccaa atttaaatga aaaaacatat gagagtatga
    17401 aagctaacat agaaaaaaat atagatgtat atttaaaaaa tatattttct atggttggag
    17461 aaaatgacac tgtctacata gcaagtgcat ttccaagtga tttagattat aaaaataaaa
    17521 gaagactctc tccaataata aaattaaatg gagaagggaa aggtatatta tcatcttcaa
    17581 ctactagaag agaaggtatt gtaacaaatt tagatgttgg ggttgaaata ttagacaact
    17641 ttaatataaa aaatcaaaat atggttggaa gaaaatatga acttattaac agagatgata
    17701 ataaagaatt tttgatggat gaatatcaaa agatagtatc tatttcaagc ataaggtcta
    17761 caatactgaa tggttttgta agcatagttt tcttgtcatg gatagttgct atgattgcaa
    17821 ttttatttag aaagcatata tcaaaaaatt ataaagaaac aacatttttt atattaaagg
    17881 aacttttaaa aataggaata gtaatgccat tgtcatttat gataacacca ataatgaatt
    17941 tcaaaacacc attagcaata tctttaggaa taattataat aacacttact atatatctta
    18001 taagtaaagt tttaataaag aacgatttaa aaaacatgct gttttttact ggaataacca
    18061 tagtaattat ggttattgat gctggatttg gctcatattt aatgaaaagc aatgttatga
    18121 gttatgactg tataattgga gctagatatt atggagtagg aaatgagtat caaggtgtgg
    18181 caattggtag tgcaatattt acatttgcaa ttttacttac atataaaaat atgccaaagt
    18241 ggtctgtaat agttttttct ttgcttatct taattacaag tgcatctcca attatgggag
    18301 caaatgttgg aagtgctatt tctgaatgtg ttgcattttt actatttata ctattgatat
    18361 ataatgtaaa gatagatttc aaaaaaatcg tattattagg tatagcagta gtatttgtat
    18421 taggagtttt tgtagcaata gatatgattt tgggaagtaa ttcacattta ggcatgtttg
    18481 taaaagaaat ttactttaat ggagcaggag aaataataca aacatttagt agaaagatag
    18541 agatgaattt aaagctagct caaaccagtg catgggtaaa tatactgtta actggaatag
    18601 gtgtaatttt agttcttatg attaatcaga ttagatactt taagcaactg atggatgagt
    18661 atccaattgt atttaaagga tttatagcat caatagcagg atgtttagta actcttttag
    18721 tgaatgactc tgggattgtg tcatcagcta cagcctttat ttatgtaatt gtacctatga
    18781 taacattaag tataaatctc acagcattaa aagaataagt actgtatgaa taatatgtaa
    18841 atattaatac attaatttaa cttctttatt tacaaaataa agaagaaagt ttataaaaaa
    18901 taaattataa taaaaaagag tttatctcaa aattgattat tctaatcaaa ttttaagata
    18961 aacttttttt attataaaga taaataacat ataacctcat attttaggta gatttttttc
    19021 ttatatgttt aggagtgcat ttaaattttt ccttaaaaat tctgtaaaat aattttgtat
    19081 tagtaaatcc atgagcttct aatatactgc ataaggtatc atttgtgtta attaaatctt
    19141 tataaatatg agaaatacgc acatcattta aatactctaa gtaagtttgt cccatatact
    19201 gtttaaattt tctacaaaaa tattctggtt gtaagtgtgc taccttagcg attttgttaa
    19261 tagaaatagg cattttgtaa ttaatctttg tatattctaa aactggttca aattttgaca
    19321 aatcaagtac tgtttttttc atatttttat tacctacaga tattttaaag tttgtatata
    19381 attcaaataa aagttcaaat aataagcttg taaagagcag attagctgca ggaggagaac
    19441 taagtttaat ttctctcatg ttttctaata taagtttaac tttacttgaa ttttttttat
    19501 agttattgtc attggcatta accttaaagt caaaatagca atttttaaaa tcagggatat
    19561 atttgtttag aaaagacaat ggtacttgca ataatataga ggtattttga taaatacatc
    19621 tagttgagtg aataattcca gaattaatga acatacactc attagctttt aaattataag
    19681 tgtaaccctc catgttaatt tgtaaatcac cagaagttat ataaattatt tctaatgagt
    19741 tatgccaatg atttgctaca taactaccac tatcatcaaa tagtttgaaa ttaacatcta
    19801 aattatcaat aggttcaatt atttcatgtg aaaaattatt tctgttcata ataatatcct
    19861 ccttataatt ttaaattata aatagtaaat ttataatgtt caatattaaa aagataatat
    19921 agactaataa attagataat aaacatactt aagaaaacgg ataaaatcaa atataataac
    19981 tgtatattaa aataacttaa aaaaattatt ttattataag tgcaaaatat acctatttaa
    20041 ataagataag aggggaggat tttatgtgta tataaaaggt gtaaatttag gaggttggtt
    20101 agttttagaa aaatggatga cctcaagttt atttgaaggc acagaagctg aagatgaata
    20161 ctatttacca agacagcttt caagagaggc atatgaatct agaattaaga ctcatcgtag
    20221 tgaatacatc acagagagag attttgcaac gattaaatct atgggattta attcagttcg
    20281 tataccagta ccatacttta tttttggaga ttgtgaacca ttcataggat gtgttaaaga
    20341 acttgataaa gcatttgctt gggcagataa gtatgggctt agtatattga tagacttaca
    20401 tacagttcca ggaagccaaa atggatttga taatggagga atatcaggta tatgtagctg
    20461 gtcacaaaat ccagaatatg tagcgtttac attaaatgta ttagaaagac ttgcaaaacg
    20521 ttatgggatg aggcatgaat tgtatggaat ccaaatttta aatgagccta taacagaaag
    20581 aatgtggaac ataatgaatg ttccaaatcg gtttaaggct gtagataagg agatggcaag
    20641 ggggagtaaa cctaattcat tagagttttt acgtgatttt tatataaaag catataaggt
    20701 aatgcgtcct tatatgagag aggaaaacgt tatagtgttt catgatgcat ttgaattaaa
    20761 agcatggaaa gactttatga gagaggaaga atttaaaaat gttgttctag atacacacca
    20821 atatttgatg ttaactgaag cagatggatg tgaacaaagt attgatagct atctcaaata
    20881 tattagagaa aattatgcta aagatatttt acaaatgcaa aaatattttc ctgttatatg
    20941 tggggagtgg agcttattta attcatatgc ttgtggtata gatacaaatg gaggtcaatc
    21001 acctctaaat gggattgaat caaatataga taaattatca aaagacgata aaagagaatt
    21061 atataggaag atagcaaaag cacagcttga tgcatggaga aatggaagtg gtcactacta
    21121 ttggaattat aagttattac tagatacagt taatgaagaa ggttggatag gatgggatag
    21181 ttgggaccta ggcaaatgtg tagctcaaga atggtatcct atagaatatt aaactaaaat
    21241 tggaggaaaa gatatgatta aaaaccctat acttccaggt tttaatccag atccttgtat
    21301 ttgtagaaag ggagatgatt attatcttgt agtttcatct tttgaatggt ttccaggtat
    21361 acctgtttat cactctaaag acttaaaaaa ttgggagtta tatactcata ttttgacaga
    21421 tgaaacaaaa atagatttga agaagcttcc ttcatctaaa ggaatttggg caccctgttt
    21481 gacttattgt gaagaagaag atttatttta tatagtttat ggaattatga actctatgaa
    21541 tgcaagatat tttgatgttg ataattattt aattacatca aaagatataa agggagagtg
    21601 gagtgaacca gtatatctac actcatcagg ttttgatgcg tctatttttc atgatgatga
    21661 tggtaaaaag tggattgcat cattagactg ggagacaaga gaaggatatg aaaaacctgg
    21721 tgttatatgt ttagtggaat actgtacaaa aaagaaagaa atagtaggat atccaaagag
    21781 aatatggtca gggggaactg atagaggttg tattgaagca ccacatataa caaagcgtgg
    21841 agattactat tatataatgt gtgcagaagg tggaactgga tatggtcata gtgtaactat
    21901 gggaagggct aaaaatatat ggggacctta tgaaaaagat tcaatgaatc caattgtaac
    21961 ttcaattcca ggcgattttt atgaaagaca tgaccctgac catctaaagc ctaaatacta
    22021 taacacagaa tcaaaacttc aaaaatctgg tcatggaagc tatatagaaa caacatcagg
    22081 tgaagtatat ttagttcatc taacatctag accatttgta ccagagttaa ggtgtacttt
    22141 aggtagagaa acagctattc aaaaaatgaa atggacaaag gataattggc ttcgaatgga
    22201 agatgaaagt aatttggcaa aagaatacgt atcagaaagt aaactagaag aacatttagt
    22261 ttcatctata ccaagttttg atgactttga ttcaaatgaa ttaggtttac agtactatgc
    22321 tcctaggatt tcaccattat catttgcaga tgttaagtct agaccaggat atgtaaggat
    22381 tagaggacaa gaatcaagaa catcattaaa taaagtgagc atattggcaa gaaaattaac
    22441 ttcagtatat gcaagaataa ccactaagat ggagttttac ccagaggtac atcagcatag
    22501 tgcgggtttg ataatgtatt atgataatat gaattatata aatttaagaa agtattatag
    22561 tgaaacattg ggtcaaagtg cactatcaat aatacatctt gaaaatggag agaaaacgga
    22621 atttttaaat actaggatac caataaaaga tataccaata tatcttcgtc tgtatataca
    22681 aggtcgtaag tcatattttg aatggagtta tgatgaaaaa aactaccaga gaataggaaa
    22741 ggtatttgat acaactaagt tttcagatga gtactgtaaa tatggagaat ttacaggtac
    22801 gtttatagga ttaacttgtg cagatcgtgt aaagcataaa cactatgctg attttgattt
    22861 ttttgaatat atagtagatg aatcaaaaga tgtcgattaa taaaatcatt actaaaattt
    22921 tcagagcaaa ggtaaatctt atgctctgaa ataagaaaca ttagaaggca aatcttacaa
    22981 aaaggagtat ggtattatga atacagaagt taatgttaaa gcaactacga ttagatatga
    23041 aaagatttca ttttttgaaa gaatttctta tggttgtggg gatttggggt gcaatatcat
    23101 atactcagct atgtcagcat ttttgctgtt ttattatact aattatgcag atgttagtgc
    23161 agcagctgta ggtagtatta tgcttgtatc taggatactg gatgggttta gtgacttaac
    23221 aatgggaatt atagtggata gaactaaatc caaatacggt aaggctaggc cttggatttt
    23281 gagaatggcg attccttttg ctatagcagc agtattatta ttttctgttc catcaaatct
    23341 tggtatcact tctaaattaa tttatatttt tattacatat aacttagttt ctactgttat
    23401 ttatacagca atcaatgtac cctatgcaac tctaaattca cttataactc aaaaccagta
    23461 tgaaagagga gtattaagta tatttagaat gatattagcc acttgtggta ccttactaat
    23521 aaatggactt acactacctc tagttgaata ctttggaaat aatttatcag catggactaa
    23581 aacattcttt gtatttggaa tagcatctat aatggtattt tttataacat ttactggaac
    23641 caaggaaaga gtaaaagcag ttaagcaaga taggaatgaa gtaataccat ttaaaatagg
    23701 tattaaatcg ttatttagaa ataagtactg gatacaaata acattatgtt tagtttgcat
    23761 atttattgta tttgcgataa atggtggttc atccgtatat tatgcaaagt ttattttggg
    23821 agatgaaaaa ttatttggtc ctataaatat ggtttcaaat atatcccaaa ttatagctat
    23881 gtttatggtt gctcctttta taaaaaaatt tggaaaaaga aatgtattaa tagtaggttc
    23941 aataatatta atatcgtcaa atgttatgtt tataatagtt ggacaaaact atataggagt
    24001 aatatttgca agtgctataa agggaatagg aagtgctgga atagcatcaa caatgtttgc
    24061 tattgtttca gatactattg aatatggaga atggaagact ggatatagaa ctgaggggct
    24121 tataaatagt gcatctagtt ttgggtttaa agtgggaaat ggattaggtt cagcaatatt
    24181 aggtgcagta ttatcaattg gtggttatgt aggaacatca gctactcaaa gtgatttagc
    24241 tatagtatca ataaaagtat gttttatata cctacctata tttataacaa tattacaaat
    24301 tatcataatg tctttttata agcttgataa agaatatagt actatactta atgaattaaa
    24361 tactaaataa tgaaaaagtt tcttataaag tcttaagttt aattaaggtc tattgtaaat
    24421 gttccctata aaaactatta tatatttatg attattgaag aatttttaga gaagcgaata
    24481 ataaaaatat aagaagactt taaatgatga aatggttggt tttttagaaa tgatttaata
    24541 agttattgtt atttaaagca ttataagtgg acaattaatt tttaatttat ggagatgata
    24601 tttaacaatt agaagtaata tataatatgc actaagaagc aatttttcaa ctatttatga
    24661 aggtggtggt acaagaaaag tatcaccttt tttttgttat acaaaaaaac agttgacttt
    24721 ttatatgaac cccttctata atgttactga aattaagtaa aatgattgaa caaatgtaaa
    24781 gataattgaa aagcttgatt ttggaggaaa gcaaatgaaa aaaattggag acttaagatt
    24841 aatgatgaag tgttgttcac tttattacga agataatttg aatcaacagg aaatagcaaa
    24901 tcaattggga atatcaagac caacaatatc aagaatatta aaagaagctt ttgaacaagg
    24961 aatagtaaaa atacagatag ttgatgtttt gaaaaatgat taccaaaaaa tagagagaag
    25021 tttggagaga aaatataaat taaaagaagt aatagtagta gatgataaac aggatgcact
    25081 aacacaaaaa caagaactag caagagctgt atctgaatat ttaactagag tagtaaagga
    25141 aaatgatata ataggtgttt caataggaac aacactaaaa gaaataccaa gatatgtgga
    25201 aaaaagtaac tgtaaaaatg ttacatttat acctctatta ggagggattg gagacaatga
    25261 aatagatatt catgcaaatc aaatagccgt aagtttagcg agggcttttg gaggtgattt
    25321 taaattatta catgctccag ctgttatgtc tgacttgtct acaaaagaga aactttgcaa
    25381 agacgaaaaa attaaagaag tactagattt aatagataaa acaactatag caattgtggg
    25441 tataggaaat cctatgagtt taaactcaac aataatggct tctggataca tgaatgaagc
    25501 agatatagaa gatttaaaaa aatacaactc aataggtgca atttgtttac aagcctttga
    25561 taaagaagga aaaacttcta tacttgaatt taatcaaaga gtattaggag tgaaactgga
    25621 agatttaaaa aagataaaaa gaacaatagg tgtcgcttca ggagatgaaa aaatagaggc
    25681 aataaaggca tcattaaaag cgaaatttat aaatagttta gcaattaatc acagtttagc
    25741 acttaaatta ttagaagatt gtgactaata gaaagataga taaaagttaa caggagggaa
    25801 tgtatatgtc aatatcaaaa gaaacattgc ttgaaatgta taagagaatg aatcaggcta
    25861 gaaaatttga agagaaagtt agttggtttt ttgcaagagg tatggttcat ggaacaactc
    25921 acttatctgt aggtcaagaa gcgtcaagtg tggcggctgt aatggcttta gaaaaaggag
    25981 atttagtatc attaactcat agaggacata gtcaatttat aggaatggga atagacctaa
    26041 ataaaatgat ggctgaactt atgggtaaag aaactggatt ttgtaaggga aaaggaggct
    26101 caatgcatat agcagatatt gagtcaggta acttaggagc aaatggagtt gtaggtggag
    26161 gtcttacaat agctccagga gctgcactta cacaacagta taaaaaaaca ggcaaaatag
    26221 ttttatgtag ttttggtgat ggagcatcaa atgaaggtac ttttcatgaa ggaataaatt
    26281 tatcttcaat atggaaattg ccaataatat tttactgtga gaataattta tacggtatgt
    26341 caacaagcat aaaacgtcat atgaatatag aaagtattgc cactagagca gcttcttatg
    26401 gaatagaagg aatatcaata gatggatata acccaataga agtatacgaa acagtacaaa
    26461 aagctgctga gaagtgtaga agaggagaag gacctgtatt aattgaaagt agaacttata
    26521 gatggttagg tcattcaaaa tcagatgcaa atgtatatag aacaaaagaa gaaatagaat
    26581 catggaaagc aaaagaccct attgaatttt taaaaaatta tcttatagaa aataatctat
    26641 ctaatgaaga tgaattagat aagattcaag aatttgcaaa gcaatcaata gaagatgcag
    26701 tagagtttgc tcaaaatagc ccaaatccaa aaatagagtc tttattagag gatgtatatg
    26761 cagactaaga atggtaaagg aggaaaataa aaatgagtac aagggaatta acatatgcac
    26821 aagcaataaa ggaagcaatg tcagaagaaa tgagaagaga tgaaaatgta atatttatgg
    26881 gagaagatat aggaatatat ggaggagcat ttggtgtatc agttggtatg atagatgaat
    26941 ttggaccaga aagagtaagg gatactccta tatcagaagc agctatagca ggagcggcag
    27001 caggtgcagc agcaactggc ttaagaccta ttatggaagt aatgtttatg gactttgtaa
    27061 caatttctat ggatgcaatt gtaaatcaag cggcaaaaat gagatatatg tttggaggaa
    27121 aagcacaagt tccaatggtt gttagatgcc caggaggttc tggaactggt tcagcagagc
    27181 aacattcaca aagtttagaa gcttggtttt gtcatgtacc aggagtaaaa gtagttgcac
    27241 cttctacacc agcagatgct aagggattgt tgaaagcagc tataagagat aataatccag
    27301 tcatatttgt tgagaataaa ttgttataca gaaaaaaagg ttttgtgcca gaagatgatt
    27361 atgtaattga aattggaaag gcagatatta aaagagaggg tactgatgtt acagtaatta
    27421 cttatggaag aatgttacaa agtgttgaag aagtagcaga gactctatca aaagaaaata
    27481 taaatgttga aattatagat ttaagaactt tatatccatt agataaagag actatagtaa
    27541 agagtgtatg taaaactggg agagttttaa tttgccatga agcagctaag actggtgggc
    27601 taggtggaga aatatcagcc ctgataacag aaagtgaatc atttgattat ttagatgctc
    27661 cagtaaaaag aatttgtgga aaagatgtgc caataccata taatccagag ttagaaaaag
    27721 cagttgtccc aagagttgat gaaatagaag aagcaataaa atctttaatt gttagataag
    27781 gagggataga tatggtggca aataaaataa aagccacacc agcagctaga agtcaggcaa
    27841 gaaaagacaa tataaaatta gataggctga ttggaagtgg agaaaatgga aggattcatt
    27901 tagtagatgt gttaaattat ttaaaagata ataaagcaaa tactactcct ttagctagaa
    27961 gaatagcaga agatttaaat atagatttag aaactatttt aggtactgga tataatggaa
    28021 agataagaaa gtgtgatgtg gaaaaattaa ctgcaaaaga aactattgta tcaactaata
    28081 catctaaatc tagtgagaaa aaagagctga aaattgaaaa tgaaaattca agcatgttta
    28141 acacagtaga aggaatattt gaaaagccaa atccaatgag agctactgta gcaaaacgaa
    28201 tgtcagaaag ttattttagt gctcctgtat ttacattcaa tatagaagta gatgctacag
    28261 aattgaaggt acttagagca aagttaatcg acacagtaaa agaatcaact ggagtaaaat
    28321 taactatgac agatttaata gtaatggcag tatctaaaat acttccaaat catcaagcct
    28381 taaattcagc atggacagat gagggtatat ttagatataa agatgtaaat atagctattg
    28441 cagttggttt agatgaaggc ttatatgttc cggtagtaaa aaatgcaaac aaaaagtctt
    28501 taaaagaaat agcaaaagaa agcaaagaac ttgcggaaaa agtaaagaca gggaaactta
    28561 tgccagcaga ccaagaaggt aatacattta caataagtaa tgttggaatg tatggtataa
    28621 ctacatttac acctataata aatatgcctt caagtgcaat cttaggggta ggtgctacac
    28681 aagataagtt tgttccagta aatggagagg ctaaaataaa acctataatg aacttatcat
    28741 taacatcaga ccatagagta atagatggaa cagtagctgc aaaattctta aaagatttaa
    28801 aagaattgtt agaaaatcct ttatcaatgc ttgtataggt tttgatattt tgttactgat
    28861 ataaatagtt tgaatagatt atattattat aattgtttca gtaaatttaa agcttttata
    28921 tattaagaat tatttttaac agtaactata tgtgaatatg atttgcttaa ttaaaatata
    28981 agaaaataaa taggaggaga gcctatgtca gtagaagtaa taatgccaaa agcaggagta
    29041 gccatggaag aaggtactat agtatcttgg ctaaagcaag aaggcgaaga agtaaagatt
    29101 ggagaaccta tactagaaat aacaacagat aaagttaata tggagataga gtcagaagga
    29161 gaaggtacac ttgctgtaat catacataaa gaggaaggtg aagtattacc agtatttaca
    29221 gtaataggtg taatagcaga aaaaggggaa aatcaagagg aagtaaaagc taaatattta
    29281 tctggaaatg tttcaaaaga agatacagtt aaagagaatc aaaatataga agttaaagaa
    29341 gaaaaaataa acaaaaaaga gtgtaatcat gattatgatg tagtggtaat aggaggagga
    29401 cctgggggat atttatcagc attaaaagca gctcttttag gtggaagagt tgctttagtt
    29461 gaagaaaata tactaggagg tacttgctta aatagaggtt gtatccctac aaagacttat
    29521 ataaaaacag cagaaatatt agaagaaatt gaccaattat caaagagagg tgtaaaagta
    29581 actgtagata aagaacagga cattaagaag gccataaaat ataaaaatag agtagttaaa
    29641 aaacttacag ctggtgttgg cggattatta aaaagtagag atgtagatgt gtttaatctt
    29701 aaagctagtg ttaaagaaga gcataaagta attttatcag atggaaaagt tttagataca
    29761 gaaaatataa taattgctac aggttccaaa gtaaggatat tacctataaa aggaatagaa
    29821 tcaaatttaa taataactag tacagaagca ttagatttgg aaacagtgcc agaagaatta
    29881 gtaataattg gtggtggagt gattggttgt gaatttgcag agatattcaa ttcaagaggt
    29941 tctaaagtaa ctatagtaga aatggaagat agagtaatcc caagaatgga taaagagtta
    30001 agcgaatctt taaaatattc tcttagtaaa aaaggtataa atgtattaac taaaaagaaa
    30061 gtttctgaat ttaaagaaga aggaaataac atattagtgt gcattgaagg tgaagagcca
    30121 ataaaagcag atttatgtct atatgctata ggaagagaag ctaatctttc tggcatagag
    30181 gacttagata ttaaaataga taaaggttca atagttgtaa atagtaaaat ggaaacaagt
    30241 atgccaagca tatatgcagt aggtgatgtt actggaggtg taatgttagc tcatgctgct
    30301 tttaaaatgg gagaggtagc agcttcaaat gctctaggtg tgaataaaga agttgactta
    30361 ggtgcattac ctagttgtgt ttatacaatt ccagaagtag catcagttgg tattacagaa
    30421 gaggatgcta gaaaaaaata taatgtaaaa gttggtaagt ttaattttgc tggaaatgga
    30481 agagctttag cttctggtca agaacaagga tatgtgaagg tagtagcaga tgctaaatat
    30541 ggagaaattt taggtataca tatgtttgga tgtggtgtag cagaacttat aaatcatgca
    30601 gcatcattta aagcgttaga gatacctact gatgaagcaa gtgagttgat atttggtcat
    30661 ccatgtactt cagaagcttt aatggaagct ttggcagatg taaatggaga atgtttacac
    30721 ttacctaaaa aataaatcta aacataaatt attaatttaa gtctattatt aatattaatt
    30781 tatatcataa aattttaaaa cacttactta gccatacccc ttattatgca aataatttat
    30841 ttgcataata aggggtattt tttatggaaa aatatagaat atagaatcct tgtagttttt
    30901 gttgtacaaa aaagatagta atataaaata acattatcat tttagaatga tttcaattgt
    30961 aattaggaaa agtgattttt ttgtttttaa aaaaagtatt atttgtaaaa tataaaaaaa
    31021 aatttcttaa tatttgaata aaagaatagc ttaatttaaa tgttattact ttataaaaaa
    31081 ataataagta caaaaaaaac aatatatggc atataagttg ctatataaat aataaggagg
    31141 gaacaattat aaatgaggca aagaataaaa aacttaattg aaaatgaaga taagaaaaat
    31201 cctttaacag atgaagtgat ttcaagtagg ttaaatattc gaagagaaga tgttaccttt
    31261 ttgagaaatg agttaaaaat agaagattca agacaaagaa gaaaagttgt tttaattaaa
    31321 gctataaaag atattttaaa agaagaaaaa actataaata aaaatgatat aacaagaaga
    31381 ttaaacagca ttgggtttac agtatcaaga tttacagtca tacaatactt aaaagagatt
    31441 caagattctg gtgacctaaa acttgataaa gagagtgatg ataaaaaaga agaaataatc
    31501 aataatagag aaaataaaga tatagcattt gataaactca taggtagtag tggtagctta
    31561 agtacaatta taaaactagc caaagcagca attctttatc cacctcatgg tcttcatact
    31621 attattatgg ggccaactgg tgttggaaag agtgagttag cagagtgtat gtataaattt
    31681 gcagtagaat catccagatt ccctaagaat gcaccattta tagtttttaa tgcagcagat
    31741 tattcagaga atccacagct tttgctatca cagttatttg gacacgttaa aggtgctttt
    31801 acaggagctg atgagaacaa agaaggatta gtatcaaagg cagatggagg aatattgttt
    31861 atagatgaaa tacatagatt acctcatgaa ggtcaagaaa tactatttca actgattgat
    31921 aaaggtatgg tcagaaagtt aggagaaaca agactaacac ataaaataga tgtaatgatt
    31981 atttcagcaa cttctgagcc aatagattct catttactta atacatttaa aagacgtata
    32041 cctgtaacaa ttgaaatacc agaattagtt gcaagaccat taaatgagag gtttgacatt
    32101 ataaataatt tcttcttaat agaagctcaa agaatgggag caaacataca tataaagtca
    32161 gatgtattaa aagctcttat gctttacgat tgtataggta atgtaggtca acttagaagt
    32221 gatattcaag tagcttgtgc taggggacta ttaaaccaac ttacaaacaa actaaaagaa
    32281 gtaaatataa gcatatcaga tgtacctgga tatgtaaaac aaggtcttat aaaaatcaga
    32341 aattgtagag gaaaaataga aaattatgta gatggggatt taattataga ctcaaatctt
    32401 caaggtgaga tagaaaagaa aaatgaagat atatatactt ttccagatga aatatacaaa
    32461 cttactgaaa gaagacatat tgatttattg gaacaaggtt tagattttga tgttataaat
    32521 agaatcattg gaggagaatt agaaagttgc attcaaaaat acataaaaca agttaaaaaa
    32581 gtttctatta gtaacaatct tccagatata agtccaattg ttggaaaata tatcgtagag
    32641 ctaacttatg aagtaatcaa aatagcatca caatacctaa gttcactaga accgaatcta
    32701 catttatgtt tagcagttca cctaaaagca gcttttgaga gattaaaaga aggaaaagta
    32761 atatcaaatg ctcatttgaa agaaataata ggaaattatc cagtagaata ttctgtagca
    32821 gaaaaggtag ctcaatattt aaaggaaaga tataacataa acttaccaaa agaagaaata
    32881 ggtataatag caatatattt taaaatgagt agtagaagag atatgtctga acaaaaaaag
    32941 ataggtgtac ttcttatggc tcacggaaga gtagcatctt ctgtatgtga ggttacaaat
    33001 aaactattag gaattaatca cgcaaggtat ttagatatgc catttgagaa gaaaccggaa
    33061 gaaatgattg aagaagctac tacaataata aaagatattg atgaaggtag aggtgtgatt
    33121 atattagtag atatgggttc actttcatat tttggagata ttatttctgg aaagactgga
    33181 attaatataa ggacaatatc tagatttgat acattgcttt ctatagaggt tatacgaaga
    33241 gcagttttac cagatttaac aatagacgag atagttgatg aagttaaagg tatagagcca
    33301 caagtaaaag aaaaggttag taaatgtaat aatacaaaag tagattttag aaaacctata
    33361 attttaacat tatgtattac tggattaggg ggagcttgta agataaaaaa aatcctagag
    33421 gaaaatatta aaagtataac tgaaaaggtt gatatagaac ctataggtat gattgaatat
    33481 ccaagtcttg atttagagat aaaacaaata agcaatgata aaaatgtaat cgccatagtt
    33541 ggaacaattg accctcagat agcaaatatc ccttttttta gtctagtaga cataaatgat
    33601 aaagcaaagt taaatcaaat aaataaccta attgatacaa atcaaattgg tgaaacaaat
    33661 aaaaaatatg aattatcaga tttaatacat aaagaagata tatttgtgga cttacaggtt
    33721 aaatcaaaag aagaagttct aaaatatatg agtaaaaaac ttagagagaa aggttatgtg
    33781 acaaaaaatt tctataaaaa agtagtggaa agagataact tatttccaac tgaattatca
    33841 gatgaaatag caatacctca cacagatgga atagatgtaa ttaggccagc tataagtata
    33901 gccatcttaa agaagcctat tgtgtggagt aaaagtaaag taaaaataat acttttatta
    33961 gctgtagacc aaaagtgttt taatccatta agcactctac tctcatttat agaaacagat
    34021 gaatttaaga agataaaaaa cattaaagat agagatttta ttagggagat gatattagat
    34081 ggagtcaatg aaaataatta gtagcaattt aatttttaaa aatattgaag tgtctaacaa
    34141 tgaagatgca ttaaagtttt tgggacaacg tttgtttgac gaacagtatg taaaagaaag
    34201 ctacatacaa gctgttgtag caagagaaaa aaagtatgct acagggttac caacagaaat
    34261 atacggagtg gcaataccac atacagatat agtacatgta aatgagccag gaatagcaat
    34321 tggaatactg aataaacctg taaaatttat aatgatgggt acagacgata ctgaaattga
    34381 tgtaaaagtt gtatttatgt tagcagtgaa agagccacaa gaacaattgc aactattaga
    34441 aaaacttatg actatatttc aagataagaa tatactaaat aatattgttg acttaagtga
    34501 agaaagtgtg agtgatttat taaactctaa attgaaaaat taaacatgta aagtatatta
    34561 aaaatgtaaa aagattatta aagatttcta actatagata tctttaaaat aaaataattt
    34621 caatgggggt gactaatgtg gctaaaaaga tattagttgc atgtggaaca ggagtatgta
    34681 cttcaacaat tgctataaac aaattaaaga aagcacttca agacattggt aaattggata
    34741 tggttaatat tacacaatgt aaagtagtag aagttgcatc aaaagcacct gattatgatt
    34801 taataatttg tactacacaa gtatctagta gtataaaaac accagtgata aatggattac
    34861 cttttttaac tggtgtcgga atggataaat taatcaatga tgtattagaa gagttagaat
    34921 tataattaaa aaaattaagg aacatggtct ctaaaattat aagttttaga gacttaaaat
    34981 taaataatgg agggtcttta tatggagata ttaaatttca ttgttggtct aggtgcacaa
    35041 gtaatgatgc caataataat atgtattttt ggtttgatat taggtacaaa actaggaaaa
    35101 tctttaagag ctggtttaac tgtgggagtt gggtttatag gtcttaacac tattatagct
    35161 ttgctaacag ataatttagg tccagctaca caacaaatgg ttaagaattt agggctaagt
    35221 ttatcaataa tagatgtagg atggccagca gcatcagcta tagcttttgc atcaacagta
    35281 ggggctttaa ttattccaat aggtcttgtg gtaaatatag ttatgctaat tactaatact
    35341 actcaaactg ttgatgtaga catatgggat tactggcatt ttgcttttac aggagcttta
    35401 gtggcagggg ctactcaaag tgtaatgtgg ggagtatttg cagcagtagc aaatatggta
    35461 attgtattgg taatggcaga tttaactgct ccaggtatag aggaatattt aggtatgcca
    35521 ggtatatctc ttcctcatgg atttacacag gcatttgttc caattgctat agtagtaaat
    35581 aaattattag acctaatacc aggcataaat aagattgaga taaatgctga tacattgcag
    35641 aaaaaatttg gattatttgg agaaccttta ataatggggt ctgtaatagg tgtaataatt
    35701 ggtattgctg cgaaatatga tataaaagga atattacaat taggtgtaac tatgggagct
    35761 gtattaatat taattccaaa gatggcagca ttattaatgg aaggattatt accagtatca
    35821 gaagctgcac aggaatttat tgagaagaga tttaaaaaca gaggcaagat ttatataggc
    35881 ttagattcag cagtaggaat aggtcatcct gttacattat cagttgcact agtgttggtt
    35941 cctttgacta tacttatagc agctatattg ccaggaaata aagttttacc atttgcagat
    36001 ttagcagtaa ttccatttgc acttgtatta atcgtaccaa ttacaaaggg aaatgtgttt
    36061 agaacattaa taataggaat aattataatt acttctggat tattaatcgc aactaactta
    36121 gctccattat ttacccaaat ggctttaaat gctagtttta aaatgcctga aggagcaact
    36181 atgatttcaa gtatttgtga tggtgcgaat ccattaagtt gggtatttgt aaaagttatg
    36241 aactataaag ttattggagg agtagttttt ggagttatag ctttaggaat ggctatttac
    36301 aataggaata gaataataaa tgaaaataaa aaactatcta tagaagaata aggttaaaac
    36361 aattttatta aggagtgtat aggttatgaa aaaatataaa tatgattcta aaaggtactt
    36421 actcagtgtt acaataccag gattttttat gattttaata ttgatttatg cactgtttaa
    36481 taactataca aattttaatt tgaatatata tagtttgtta ataattgtct gtacttatgg
    36541 tatattcaat actttcatat catcaagtaa tcctaaaaaa attattattg acagcaaatg
    36601 tatacatttt acctcattta tgactacaca taagtatgaa attaaagata tagaaaagat
    36661 aagaataaga gaattttata ataaaaaaat ttatctaaaa attaatgatg gaaaactttt
    36721 caaaggtagg tattggataa gaacaaatat gtttaataat agtatagcat tatatagcta
    36781 tttcattgag ttggaagagt gcttatatcc agattcacta aaatttagaa ataaaaaatt
    36841 tgagaataag aacatataaa aataaaaaat tgaattgaag cctggcttaa tcttttttga
    36901 taagatataa gtttgaactt tatactaaat ttttagaatt ttcaatcaag acaataacag
    36961 aatagctaag caattagaac acaattaaga tgtataaggc atgtatatga tgaatgggag
    37021 gatttaatta atgttattag agaaattaag aaaagaagta ttacaagcat ctttagacct
    37081 tttaaactat aatttagtga cattaacagg aggaaatgta agtgggagag atgaacaaac
    37141 tggctatata gcaatcaccc caagtggaat ggattataga aatcttacag caagtgatat
    37201 tgttatagta gatgtagatg gaaatattat agatggaaaa tggaaagcat cagtggattt
    37261 atcagaccac ttgtatatat ataagcatag agaagacata aatagtataa ttcatacaca
    37321 ttctacatac tcaagttgtt ttgctatttt aaatgaacct atagaatgcg caagtacaac
    37381 tcttgcaaat gaagtagggg gttcagtacc agttgcaaaa ttttcaccac caacatctaa
    37441 aaagatggga aaatgtgtta ttgaagcaat tggtgacaaa agagcatgtc ttttagcaaa
    37501 tcatggcgta attgcagttg gtccatctgt aggacatgct cttacagccg ctgtaatgtt
    37561 agaagattca gcaaaagtat attacttagc aaaatcaatt ggcacaccag tgctactgcc
    37621 tgatgaagaa attcaaagag cgagagatgt attttttaat gtctatggtc aggataaata
    37681 aattagataa aattttaaaa gtaatatgaa aatatagata ttcaatgata ttaaggagat
    37741 ttataatgat ataataagtt taatagttaa gaagtaaaat atgaaatgta atagtatata
    37801 aattcattta agactaaaaa gaataagata aaataaaaag gagtctgtat ttctatgtat
    37861 tacttattaa acaaaagcac aaatccttac tttaatttgg cattagaaga atatctattt
    37921 ttaaatgata aatataatga tgatattata atcatatgga gaaatgaaga atccattttt
    37981 ataggtaaaa atcaaaatcc atatcaggaa gtatatcatg atgttattga aaagggagaa
    38041 attcctattt taagaagaat atctggagga ggaactgttt atcatgactt aggtaatatc
    38101 aatatgtcat tcatacaaaa agataggcaa cttcatgaga tagatttttt ggagcatact
    38161 aagtttatgc aaaagatgct ttcaacctta ggactagatg tatctataac tgaaagaaaa
    38221 gatttatttt taaatgggaa aaaaatttca ggttctgcac agtctataaa aagaaaaaat
    38281 tctctttatc atggaactct tctttacgat tcagatttaa ataaattaac taaatattta
    38341 aattcaaata aagcaactga atcaaatgca actaaatctg tttcaagtaa agttacaaat
    38401 attaagtttt tactcgaaaa agatataaat tactttttag attattgtgt tgaatattta
    38461 aaatctaata taaagaatat aaaagaactt gaattggatg aagaagatat taaaagtgta
    38521 tacaatatag gagaagataa atataaaaag atagagtgga catatggtaa aacgccgaaa
    38581 tttcaagtag tgctaccatt taataatgaa agtaaaataa atatacatgt taacagatgg
    38641 aaagtatcaa aattttttat ttcttatgat gataatgtaa ttaatatgga caagttgtta
    38701 gatttgaatt tctttaaaga agaaataaaa gagagtattt tagaaaatta tccacattac
    38761 atagatttaa tcaatttaat attttaatat aaaacctcta atttgataaa attgtcttat
    38821 atcaaactag aggtttttaa tattcttgca tattaacaac cattacaaaa ttgtaaaatt
    38881 aaaaacaaca ctattgaaaa atcaatatat atttgtttaa atatatgtgt ttttcattag
    38941 caaatagaca ttaactattt atacaactga aaatttaata tataattaat cagatggtta
    39001 aaataaaaat attaaaagtt ttaataaatg atggttaaaa ataaaatacg aggtgatacc
    39061 atgtatagtg ttataattgt tgcagcggga agcggaagga gaatgaactt agatataaac
    39121 aaacagttca taaaattaag agaaaaagaa attattgctc atacaattca agttttttat
    39181 gaaaatataa atatagatga aatagtggta tgtataaaaa aagaagaaga agattttttt
    39241 aaagaaaata taataaataa gtataacttt aaaaatataa aaatagcata tggcggaaaa
    39301 gaaagacagg actcaatata taatggttta aaaaaattag ataaaaattg tgatatagta
    39361 cttatccatg atggagcaag accatttgtc gaccatagaa taatcaacga atctataaag
    39421 gtagctaaag aaaaaaaggc tgtggttgta ggtgttccag taagtgatac tataaagata
    39481 gtgtcagatg gaacagtaaa agaaactcca gaaagaaatt tgctgtgggc agcacaaacc
    39541 cctcaaacct ttgaatataa tctcataata gatgcttatg aacaagcata taagaacaat
    39601 tattatggta ctgatgattc aatgttggta gaaaatatag gtcaaagtgt cactatggta
    39661 atgggttctt atgaaaacat aaaaataact agtccagaag atttaaatat agcagaacaa
    39721 atattaaata tggaaaaaag agatgaagtt aacagtagaa ggagaattat atgagaatag
    39781 gattaggata tgatgtacac aaattaacag aggatagaaa acttataatc ggtggtgtag
    39841 agataccaca cgataaaggt ttgttgggtc attctgatgc tgatgtattg atacatgcaa
    39901 taatggattc tattttaggt gccctagcat taggagatat agggaagcat ttcccagata
    39961 cagatgaaga atataaggga gcagatagta tgaaattatt agaacatgtg tataatctaa
    40021 taacaagtaa aggatataaa attggtaata tagacagtac tataattgct caaagcccta
    40081 agatggctcc atatattgag agtatgagaa gtaatatatc aaaagtttta aacacagaca
    40141 ttgataatat aaacataaag gcaacaacag aagaaggtct tggttttaca ggagcaaaac
    40201 agggaatagc ttcacaaagt atttgtttat tattgttgac aagtcagaat aattaatata
    40261 ttattagtaa taagtttaat ggatatcaag taataggcct atatagaata tctataatgt
    40321 atgaatttaa gtgaaattaa tataaatata aaattagcta tgataaagaa atagtaaaat
    40381 gatgaaatct tcacagagag aaaacggtgg tgagagtttt caagaggaag tctttgaacc
    40441 tgtcttttag cttaaaggta taaaaatctt tacggtagga accgttatat tcccaaaaga
    40501 gagctattca tatagctaac tagagtggta ccgcggaaat taaacctttc gtctctatac
    40561 ttgtatagag atgagaggtt ttttatattt tcaggaagtt aatattcagg aggaatctat
    40621 taatgaaaat gtcaaaaatg tttatgccga cattaaaaga aatcccagca gatgctgaga
    40681 ttacaagcca tcaattaatg gttaggtcag gcatgataaa aaaaatgact tcaggtgttt
    40741 ataaccaatt accaatgggg ttaagagtgt tcaaaaaaat tgaacaaata attagagaag
    40801 aattaaataa aaaagattgt caagaaatac tttgtgcagc cttacttcct tctgaattat
    40861 ggaaagagtc tggaaggtgg actgctatgg gtgaagaaat gtttagacta aaagacagaa
    40921 cagaaagaga gtactgtctt gggccaacac atgaagaagc attcactgat ataataagac
    40981 aagaaattac ttcatataaa caattgccac taaacttgta ccaaatacaa gtaaaatata
    41041 gagacgagag aagaccaaga tttggtgtta tgagaactaa gacttttaca atgaaggatg
    41101 catatagttt tgatgtagat gataaaggtt tagataagtc atatcaagat atgtttgatg
    41161 catatgtaag tatatttgat agatgtggat tggagaatag ccctgtacag gcagattcag
    41221 gagctatagg aggttctaca tcagccgaat ttatggttaa gtcagaagtt ggtgaagatg
    41281 aagttgtatt ttgtagtgga tgtgattatg cagccaatgt agaaagagca gaatcttgta
    41341 atctagcatc acaaaaagaa gaaatgaaag aattagaaga ggttcataca ccaggagcag
    41401 ctacaataaa agagttagaa gaatttttaa aaacttctcc agataagttt gctaaaactt
    41461 tagtatatga ggcagatgga aaaacagttg tagtcgttgt aagaggagat agagaagtta
    41521 atgaaatcaa agtatctaat gccataggtt ctgttataga atttgctctt gctacagatg
    41581 atgtagtgag aaaagtaact aatgcagaag taggatttgc aggtccaata ggtataaatg
    41641 ctgactatgt atttatagat aaagaaattg ttgaacaaag aaacatagtt gttggggcta
    41701 ataaaactga gtaccatata aaaaatgcta actatggaag agattttgaa ggaatagttg
    41761 gagattttag aaatgttcaa gaaggcgaca agtgtatagt atgtggtaag ccacttgaaa
    41821 tagctagagg tgttgaagta ggacatatat ttaaactagg aactaagtac tcagaatcta
    41881 tgaatgcaaa cttcatagac aaagatggaa aatcaaagcc tatagtaatg ggatgttatg
    41941 gaataggtgt tgaaagaaca gcagcagcta taattgaaca acataatgat gagaaaggta
    42001 taatatggcc tttgtcagta gctccatacc atgttgtgat agttccagca aatatgaaaa
    42061 atgaagaaca aatatcaata gctgaaaata tatataatga tttgcaagct atgggtgtag
    42121 aagttttatt agatgacaga gatgaaagaa taggtgtcaa attcaatgat tcagaattaa
    42181 taggaatacc tatgaggatt acagtaggta aaaatattaa tgaaggtaaa gtagaattta
    42241 aacttagaca taaagaagat aaagagataa ttgacataga agaaataaat gaaaaagtaa
    42301 aggcagagtt tatcaggaat aatgttaggt taggataata acttaaataa gatattgtat
    42361 agataatcaa agttgtactt tatagacacc attttatcta tatataagga tataaaatgg
    42421 tgttttttta taaaacaaat aaatgaggag gtaattaaaa tggcaaaaaa tgaaaaacaa
    42481 tttgttgaag aaataacaaa gatggaagat gattttccac aatggtacac agatgtaata
    42541 actaagactg acttagttga ttatgcacca gtaaaaggtt ttatggttgt aaagccatat
    42601 ggatatgcat tatgggaaaa aatgcaagaa tttatggata aaaaatttaa agaaactgga
    42661 cataaaaact gttattttcc attattaata ccagagagtt tattaaacaa agaagcagaa
    42721 cacgttgaag gttttgctcc agaagttgca tgggtaacac atggaggaaa taaaaaatta
    42781 gaagaaagat tatgtgtaag acctacttca gagactataa tatgtacaat gtatgcgaaa
    42841 tggttaaaat catatagaga attaccatat ctttataatc aatggtgctc agttgttaga
    42901 tgggaaaaat caactagacc tttcttaaga acatctgagt ttttatggca agaaggtcat
    42961 acattacatg aaacagcaga agaagcacaa gaagaaacaa tacaacaatt agaagtatat
    43021 aaagcgctat gtgaagaatt acttgcaatg ccagttgtag ctggtcaaaa aagtgaaagt
    43081 gagaaatttg caggtggtga aagaacatat actatagaag ctatgatgca tgatggtaaa
    43141 gcattacaat caggtacaag tcacttccta ggtcaacact ttactaaggc ttttgatatt
    43201 acttttgcag atagagaagg aaatttagct aatccatacc atacatcttg gggagcatct
    43261 acaagactta taggtggact tataatgact catagtgata acagaggttt agtattacca
    43321 ccaagagtag ctccaattca agttgttata gttcctatag ctgctaaaaa aggaaatgta
    43381 atggagactg ttgataaaat atatgctgat ttaaaagcta agggagtagc tgtagaagtt
    43441 gatgatagag ataactatac aactggatgg aaatttaatg agtgggaaat gaaaggtgtt
    43501 ccagtaagag ttgaaattgg accaaaagat atagaaaata atcaagctat ggtatttaga
    43561 agagatactt tagaaaagga ttctatgcct ttagaaggat tagctgatgc tatatgtgat
    43621 ttatttgatg ttatacacaa tgatatgttt gaaaaagcaa gaaaacatag agaagacaat
    43681 acatctatag ttgaaaatat ggatgagttt agaaaagctt tagaagaaaa gccaggattc
    43741 ataaagacta tgtggtgtgg agatgcagaa tgtgaagcta agattaagga agaaacagga
    43801 gcaactataa gatgtttacc ttttgaacaa gaaaacttag gtcacaagtg tgtgtactgt
    43861 ggaaaagaag cagatagtat ggtagtaatg gcaaaagctt actaaaatac atttaaataa
    43921 aaactggggt agaaagtatt taatacttta tcccagtttt ttgtttttta tgagtaataa
    43981 aatgtatttg taactatgtc ataagataag tcatagatac ttatattaaa aagaatataa
    44041 tagagaacta tttttaataa ttacatatta atgaaagcaa aatattttgt tatatagatt
    44101 ttcaataaag caaacaataa atataaatga atattaataa ggagtgcttt taatttttag
    44161 aaaataaatg acttaaaaga aagatttatg aaattaaaac taggattttc tgatataata
    44221 aacatgtgta tttttaaata aaaaggatat tattattaga tttgattaaa aataaacttg
    44281 caaaacaatg tactagttta atattatagt tatattgaat aaaatatcag gaggaagtaa
    44341 aaatgaatgt aagagtaagg tttgcaccaa gtccaacagg atttgtacat ataggtagtt
    44401 tgagaactgc tttatataac tatttatttg caaaaaaaat gggcggagaa tatatattaa
    44461 gagtggaaga tacagaccaa agtagattag tagaaggtgc tatagagaat atgcttaatg
    44521 ctatgaaatg ggctggtgtc aaccatagtg aaggtgttat attagatgat agtggaaaag
    44581 tagtacaaaa aggagaatat ggtccatata ttcaatctca aagattagat atataccaag
    44641 aatatataaa gcaactttta gatagtggaa aagcttatta ctgtttctgt acaaaagaaa
    44701 gactggatga agtaagagat gctcaaagag cagcaggaga aacagctaaa tatgatggtc
    44761 attgtaagaa tctttctaaa gaagaagtag aagcgaatat aaaagcagga ataccatatg
    44821 ttataagatt aagattgcca gagaatcata caattaagtt tacagactta gttagaggag
    44881 atatggaatt taatactaat gacttagatg accaagtatt aatgaaaaca gatggatttc
    44941 caacttatca ttttgcagta gttgttgatg actatttgat gaaaattaca catgttataa
    45001 gaggagaaga atgggtatca tctactccaa aacatgttta tttatatgaa gcttttggat
    45061 gggaagcacc tgtatttgtg catttaccaa atatacttaa taaagaaaag aaaaaattaa
    45121 gtaaaagaca aggtgatgta gctgttgaag actttaagaa aaaaggatat ttaccagagg
    45181 gattagtaaa ctatgtagca ttagttggtt ggtctcctga agataatcaa gaattgttta
    45241 caatggagga attagaaaaa gccttctctg tagaaagagt atctaaaagt ggtggagtat
    45301 ttgatactga aaaattaaat tgggttaatc agcactatat aaaagatggt gatgatgctt
    45361 atctaacaga cttagcaata ccatttttaa tagaagatgg atttataaca gaagaagaag
    45421 ctactaataa atatgatttc ttaaagagta tgatatcagt acttaaagag aaattacaat
    45481 atgtaaaaga agttactgaa catgcaagta tattttttgg agataaaata gaggtagaaa
    45541 ctgaagaggg aagagagttc ttaagattag aacatatacc tactttaata gatgctttga
    45601 gagaaaaaat agaaaaaaca gaggtattaa atgctgagtt tgttcaagct atgcttaaag
    45661 aaatacaaaa agagtacaaa ataaaaggga aaaatttatt tatgggctca agaataattt
    45721 tgacagggca aatgcatggt ccagatttac caaaagtaat ggaagtttta ggaaaagaaa
    45781 cttgcttaaa tagaatagct tatgtaaaaa ataatatatt atagtcataa aagtccgcta
    45841 atttagaagc ggactttttt tgtgttagta tttggtgaaa atatctgctt aagaaaatga
    45901 aggtatttaa ggtaataaat ttaatatata aaaagcaaag caaaaatata aataaaatat
    45961 gaataataaa ctaataaaat attaagcata gaagaaggga atctattatt ttagtttgat
    46021 ttaattatta agggggtaat tactatgtat agtaatattg atgatgttaa aaaggaatta
    46081 aaggagctat gcttagaata tgttacaatt ttagaaaaat taaaagatga aaaaatgatt
    46141 acagaagaaa cttttgaaaa gtgctcttct caaaaaaaaa tatttttaga agaacaatag
    46201 aggatggtaa tagtattatt attatgtagt ttgaaagata gtacgaaaaa tgatagtaat
    46261 actattattt attgcaattt tcaactataa tataatatat aatgttaaga agataattta
    46321 taaaaataca gtgaggtgat gagtgtgaaa gtttataata cattgactag aacaaaagaa
    46381 gaatttgttc cattagaaga aggaaaggta aaaatgtatg tgtgtggtcc aacagtttat
    46441 aactatatac acataggtaa tgcaagacca tttataatat ttgatactct aagaaggtat
    46501 ttagagtata gaggatatga tgtaacttat gtacaaaact ttacagatgt tgatgataag
    46561 attataaata gaagtcatga ggagggaata tctcctgaag aagttgcggc taagtatata
    46621 aaagaatatt ttgtagactg tgatgggcta ggaataaaaa gagctactgt tcattctcag
    46681 gttacagata atatacaaca gattatagag tttataaaag agttggaaga taagggatat
    46741 gcatatgcag taaatggtga tgtatatttt gatacaaata agtttgaagg ttatggaaaa
    46801 ctttcaggtc aaaaacaaga agatttagag gcaggggcta gaattgaggt taatgaccaa
    46861 aaaagacatc ctatggactt tgttctttgg aaggcaaaaa aagaaggtga gccaggatgg
    46921 gatagccctt ggggagaagg tagaccagga tggcatatag aatgttctgt tatgtctaag
    46981 agatatttag gtgaaacaat tgatatacat gcaggtgggc aagatttaac attcccacat
    47041 catgaaaatg aaatagctca aagtgaagct agaagtggaa aaacattctc aaaatactgg
    47101 atgcataatg gatatataaa tataaatgat gaaaagatga gtaaatcaaa aggtaatttc
    47161 tttacagtaa gagatatatc aaaattatat gatttagaga tagtaagatt tttcatgtta
    47221 tcagcacatt atagaaatcc agtaaacttt agtgatgaga tgttaaatca agctaaagca
    47281 ggtcttgaaa gactatataa tactaaagaa aaattagaat ttacgctaag taatttagta
    47341 gaatctcctt taacagaaaa agaagtagag cttgttaaag aattagatga ctttagacaa
    47401 aaattcatag atgctatgga tgatgatgtt aatacagcag acgcagtaag tgtaatattt
    47461 gaattagcta agttaataaa ttctaatgta gatgaaaatt cttctttgga gtttgctaaa
    47521 aaatgcttag atgaatttaa tgaacttaca ggagtattaa atattgtaaa taagaaaaag
    47581 gatactgtat tagataaaga cattgaagaa ttgatacaaa aaagaactga tgcaaagaaa
    47641 aataaagagt ttcaattagc tgatgatatt agacaacaat tactagatat gggaattgta
    47701 ttagaagaca caagacaagg tgttaagtgg aaaaggatat aaaaatggaa aaaactgaat
    47761 tagttactat gtcaccatta gttttagcat acttaggtga tacagtgtat gagacatata
    47821 taagagaata tttaattaga cagaatacac aaagaaaagt taatgatttg cataaactag
    47881 ctataaagta tgtaaaagct aaagctcagg caactataat tcatgaaatt gaaattgagt
    47941 taactgaaga agagagtaaa atttataaaa ggggaagaaa tcaaaagtca aatacttctc
    48001 ctaagaatgc agatattata gactacaaac atgcaactgg gtttgaggca ttagttggat
    48061 atttgtattt aaataatgaa atagagagac ttcaatatat tatcaataaa ggaatcaaaa
    48121 ttattgaaag agatatgtaa atattaaaga gtgttgtctt aataataagt aataaggcaa
    48181 cacttttttt ataactaatg tataataaat atatagaaat tagtaatgag aaaggataaa
    48241 aagttatgaa agtaaaatta atatcacata cacctgaacc agaaaaagta atagctatgg
    48301 cagctaagct atgttattca ccagttggga cagacgaaat agaaaaagac ttaacagatg
    48361 aaagtataga gaaattttta aatatgttat taagtatagg tcatgggtca atattagaac
    48421 atgcttcatt tacattttca atagaaggta tttcaagggc atgttcacat caaattgtta
    48481 gacatcgtat agctagtttt tcacaacaaa gtcaaagata tgttaaatta gaacaatttg
    48541 agtacataat tcctccagaa atagaaaaaa tagaaaaggc aaaagagtta tttatagact
    48601 ccatgaaaaa agaccaagag aattatgata agttagttga aatattgttt gaaaatcatt
    48661 ataatgacct aataaaaaac ggtaaaaatg agaaaacagc taaaagacaa gctgagaaga
    48721 aagcaataga agatgctaga tacgtatttc caaatgcatg tgaaacaaaa atggtattta
    48781 ctataaatgc tagaagtttg tttaatttct ttgaacatag atgctgtgaa agagcacagt
    48841 gggaaataag aaatttagct gtggaggtgt taagagaggt taaaaaggtt gctcctatat
    48901 tatttaaaaa gactggtcca agttgtgtaa atggaagttg tccagaagga actatgactt
    48961 gtggagatat agttcaagtt agagaaaaat ttaaggcctt gtaggaggtg aataatttgg
    49021 cgagtataga aggaagaaat ccggtaatag aagcaataaa aagcgacaga gaaatagata
    49081 aaatattaat tgcaaattca gctaaagaag gttcaattaa gaaaataata ggaatggcta
    49141 aagataagaa tataattatt cagtatgttg ataaacataa gttagatgaa gtaagtacaa
    49201 gtcattcaca tcaaggtgta atagcttatg caagtgagta taagtattat gaattagatg
    49261 agctaataga tttagcaaag aataaagatg aagacccatt tttcattata ttagatgaga
    49321 taacagaccc acataatttg ggttcaataa taaggacagc agatgcagta ggagcacatg
    49381 gagttatcat tccaaaaaga aggtctgtac acataactcc tgtagttgcc aaagcatctg
    49441 ctggagcagt agaatatatg ccagtttgca aggtaaccaa tatagttaat acaataaaaa
    49501 gactcaaaga agaagggctg tggattgctg cagctgatat ggatggagaa actttttata
    49561 aacaaaatct tactggtcct cttggtgtag taattggaag tgaaggtttt ggaatatcta
    49621 gattggttaa acaaaactgt gactttatag taaaaatgcc aatgataggt aatgttacat
    49681 ctttaaatgc atctgtagca ggtggaatac ttttatatga gatattcaga caaagactgg
    49741 ataaaagtaa ataggcatga aaaaaaatat aaatcattac ttaataatag atggctacaa
    49801 tattataaat gcgtgggaca atttgaaaga actggctaaa gaggacttag aagattctcg
    49861 agaaaagctt attgatgaca ttatagaatt ttctgagttt atgggttata agactataat
    49921 agtttttgat gcttataatg ttaaaaattc tcgagaaaaa gttgaaaaaa gaaaacacat
    49981 aacaatagtt tatacaagag aacaccaaac agcagatagt tatatagaga aatttataac
    50041 ttctttatca aagtatgatg atgtaaaagt agccactaat gactatgcag aacagcaaat
    50101 gattttagga aaaggtgcta ctagaatgtc tgcaagagaa ttaaagttag agttagatcg
    50161 ttccaagaat aaaatgaagg aaaaaaatat cggtttgagg aaaaaaattc agcgaaattg
    50221 gttggaggaa aggttagata aagaaacatt gtcgaaactt gagaacattc gtagaaagcg
    50281 ttgaaattac taggttcttt agactataat atacctataa atttgtttta tatatggggg
    50341 agatttacat gttggtagca aaagaaaaaa gttatgagtt agtggacaat tgtcagcagg
    50401 atgagtataa cattgtatta agagcaagtg aaggggataa aatagcacta gagtacatta
    50461 ttactaaata cagaaatttt gtaaaggcaa aagcaaagtc atatttttta attggagcag
    50521 ataaagaaga tataatacaa gaaggaatga taggccttta taaggcagtt agagattttg
    50581 atggaagtaa gaccaattca tttaaatgtt ttgcggagat atgtataaca agacaaataa
    50641 taactgctat aaaaactgca acaagacaaa aacatatacc tttaaattca tatgtttctt
    50701 tgaataaacc aatatatgat gaagagtcag acagaacact tttagatatt atagctacaa
    50761 gtatagtaac agatccagaa gagcttataa ttagtaaaga agagttaaaa aatatagaat
    50821 caaaaatgaa cgaattgtta agtgacttgg aattagaagt actagaatta tatttaaatg
    50881 gaaagtcata ccagtttata gcggacaagc ttaaaagaga tgtaaagtca atagataacg
    50941 ctttacaaag ggttaagaga aaattagaaa aacatcttga aaacagaaat gattaatagt
    51001 aaaatactta ccataagctt attgtgagca aaattaattt atatcgaaag ataagggagg
    51061 aaattcaaaa tggctaaagc taaatacgaa agaacaaaac ctcatgttaa tatagggaca
    51121 ataggacacg tagaccacgg taaaactaca ttaacagcag caataacaaa aacattatat
    51181 gacagatatc aattaggaga agcagtagat ttcgcaaaca tagataaagc tccagaagaa
    51241 agagaaagag gaatcacaat atcaacagca cacgttgagt atgaaacacc aaatagacac
    51301 tatgcacacg ttgactgccc aggacatgct gactacgtta agaacatgat aacaggagca
    51361 gcacaaatgg acggagcaat attagtttgt tcagcaacag atggaccaat gccacaaaca
    51421 agagagcata tactattatc aagacaagtt ggagtaccat atatagtagt attcttaaac
    51481 aaatgtgaca tggtagatga tgaagagtta ttagagttag tagagatgga agtaagagat
    51541 ttattaacag aatatgattt cccaggagat gacactccaa tagtaagagg ttcagcatta
    51601 atggcattag aagatccaaa gagtgagtgg ggagataaga tagtagaatt attcgagcaa
    51661 atagatgagt atataccagc tccagagaga gatacagata aaccattctt aatgccagta
    51721 gaggacgtat tctcaatcac aggaagagga acagttgcaa caggaagagt ggaaagagga
    51781 gtact
//
LOCUS       DAGQVA010000020        48641 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.020, whole genome shotgun sequence.
ACCESSION   DAGQVA010000020 DAGQVA010000000
VERSION     DAGQVA010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48641
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.020"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..317
                     /locus_tag="MIV85_001354"
     CDS             <1..317
                     /locus_tag="MIV85_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBY2960703.1"
                     /translation="EDLQVKNMIRNSKLSRLISDVSWSEFIRQLEYKANWYGRQIVKV
                     GKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQ
                     NK"
     gene            468..1685
                     /locus_tag="MIV85_001355"
     CDS             468..1685
                     /locus_tag="MIV85_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBY2960704.1"
                     /translation="MLIGLIAAFGLVLQKKKASDVIKGSLLAAFGIIIMETGTGMLVS
                     SIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAIHLMIARFTPIKTIF
                     LTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPWLLRKYVFDVIGDDS
                     FTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREISISGGMAVFLMFIVV
                     GIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQIMPAFQGISEKVVPN
                     ALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILIYNYFNVFNLLLIPLVITSFFECG
                     AAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNWILIFGGNDLSLFGI
                     ISRFIGSLFGGIL"
     gene            1688..2428
                     /locus_tag="MIV85_001356"
     CDS             1688..2428
                     /locus_tag="MIV85_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBY2960705.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            2751..4061
                     /locus_tag="MIV85_001357"
     CDS             2751..4061
                     /locus_tag="MIV85_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBY2960706.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            4159..5076
                     /locus_tag="MIV85_001358"
     CDS             4159..5076
                     /locus_tag="MIV85_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBY2960707.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            5092..5901
                     /locus_tag="MIV85_001359"
     CDS             5092..5901
                     /locus_tag="MIV85_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBY2960708.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDTMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            5959..7707
                     /locus_tag="MIV85_001360"
     CDS             5959..7707
                     /locus_tag="MIV85_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBY2960709.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVSTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            7969..8991
                     /locus_tag="MIV85_001361"
     CDS             7969..8991
                     /locus_tag="MIV85_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBY2960710.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            8996..11302
                     /locus_tag="MIV85_001362"
     CDS             8996..11302
                     /locus_tag="MIV85_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBY2960711.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKKILDSKPSEKKEKSIDEFEPMEYI"
     gene            11274..12389
                     /locus_tag="MIV85_001363"
     CDS             11274..12389
                     /locus_tag="MIV85_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960712.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            12407..13825
                     /locus_tag="MIV85_001364"
     CDS             12407..13825
                     /locus_tag="MIV85_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBY2960713.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPNIILPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            13840..15048
                     /locus_tag="MIV85_001365"
     CDS             13840..15048
                     /locus_tag="MIV85_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960714.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(15122..16510)
                     /locus_tag="MIV85_001366"
     CDS             complement(15122..16510)
                     /locus_tag="MIV85_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBY2960715.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            16851..18185
                     /locus_tag="MIV85_001367"
     CDS             16851..18185
                     /locus_tag="MIV85_001367"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBY2960716.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(18327..19244)
                     /locus_tag="MIV85_001368"
     CDS             complement(18327..19244)
                     /locus_tag="MIV85_001368"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBY2960717.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            19452..20336
                     /locus_tag="MIV85_001369"
     CDS             19452..20336
                     /locus_tag="MIV85_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBY2960718.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            20549..22390
                     /locus_tag="MIV85_001370"
     CDS             20549..22390
                     /locus_tag="MIV85_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HBY2960719.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            22695..23402
                     /locus_tag="MIV85_001371"
     CDS             22695..23402
                     /locus_tag="MIV85_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960720.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            23396..24706
                     /locus_tag="MIV85_001372"
     CDS             23396..24706
                     /locus_tag="MIV85_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960721.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            24823..25506
                     /locus_tag="MIV85_001373"
     CDS             24823..25506
                     /locus_tag="MIV85_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960722.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            25499..27886
                     /locus_tag="MIV85_001374"
     CDS             25499..27886
                     /locus_tag="MIV85_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBY2960723.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAIYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            28166..29308
                     /locus_tag="MIV85_001375"
     CDS             28166..29308
                     /locus_tag="MIV85_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBY2960724.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            29327..29851
                     /locus_tag="MIV85_001376"
     CDS             29327..29851
                     /locus_tag="MIV85_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBY2960725.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            29951..30769
                     /locus_tag="MIV85_001377"
     CDS             29951..30769
                     /locus_tag="MIV85_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2960726.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSQLFAKKLEESLNPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            30847..31158
                     /locus_tag="MIV85_001378"
     CDS             30847..31158
                     /locus_tag="MIV85_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBY2960727.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(31285..33288)
                     /locus_tag="MIV85_001379"
     CDS             complement(31285..33288)
                     /locus_tag="MIV85_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBY2960728.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYENMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITYPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDSSI"
     gene            complement(33441..34079)
                     /gene="recX"
                     /locus_tag="MIV85_001380"
     CDS             complement(33441..34079)
                     /gene="recX"
                     /locus_tag="MIV85_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBY2960729.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            34355..35044
                     /locus_tag="MIV85_001381"
     CDS             34355..35044
                     /locus_tag="MIV85_001381"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBY2960730.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            35045..35617
                     /gene="yqeK"
                     /locus_tag="MIV85_001382"
     CDS             35045..35617
                     /gene="yqeK"
                     /locus_tag="MIV85_001382"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBY2960731.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            35734..36084
                     /gene="rsfS"
                     /locus_tag="MIV85_001383"
     CDS             35734..36084
                     /gene="rsfS"
                     /locus_tag="MIV85_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBY2960732.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            36438..38858
                     /locus_tag="MIV85_001384"
     CDS             36438..38858
                     /locus_tag="MIV85_001384"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBY2960733.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            39694..40362
                     /locus_tag="MIV85_001385"
     CDS             39694..40362
                     /locus_tag="MIV85_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBY2960734.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(40680..40952)
                     /locus_tag="MIV85_001386"
     CDS             complement(40680..40952)
                     /locus_tag="MIV85_001386"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBY2960735.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(41183..41604)
                     /locus_tag="MIV85_001387"
                     /pseudo
     CDS             complement(41183..41604)
                     /locus_tag="MIV85_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(41623..41721)
                     /locus_tag="MIV85_001388"
                     /pseudo
     CDS             complement(41623..41721)
                     /locus_tag="MIV85_001388"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            42004..43374
                     /locus_tag="MIV85_001389"
     CDS             42004..43374
                     /locus_tag="MIV85_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBY2960736.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            43733..43891
                     /locus_tag="MIV85_001390"
     CDS             43733..43891
                     /locus_tag="MIV85_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960737.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   44177..44534
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=44177..44205
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(44676..44773)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            44999..45382
                     /locus_tag="MIV85_001391"
                     /pseudo
     CDS             44999..45382
                     /locus_tag="MIV85_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(45571..46566)
                     /locus_tag="MIV85_001392"
     CDS             complement(45571..46566)
                     /locus_tag="MIV85_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBY2960738.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(46687..48315)
                     /gene="aspD"
                     /locus_tag="MIV85_001393"
     CDS             complement(46687..48315)
                     /gene="aspD"
                     /locus_tag="MIV85_001393"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBY2960739.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        18618 a         5528 c         8139 g        16356 t
ORIGIN      
        1 tagaagattt acaagtaaag aatatgatta gaaatagtaa actatctcgc ttaatttcag
       61 atgtatcatg gtcagaattt attcgtcaat tagaatacaa ggctaattgg tatggtagac
      121 aaattgtaaa ggtaggtaaa ttctttgcta gttcacaaat atgtaataaa tgtgggtata
      181 aaaacgagga agttaaggac ttaaatataa gagaatggat ttgtcctagt tgtaatgaaa
      241 ctcacgatag agatataaat gcaagtataa atatattaaa agaaggatta agactaataa
      301 cgattcaaaa taaataacat atgtaagaac cgtaggaact acggggatag cctgtggaga
      361 attagtaaga catattttag tatgcaaaat tctatgaagc aggaaccctg tgactttagt
      421 catgggaggt tcagtttatt tcaaataata ttttacgtaa tccatctatg ttaattggat
      481 taatagcagc atttggtctt gtactacaga agaagaaagc atctgatgtt ataaaggggt
      541 cactacttgc agctttcgga attataatta tggagactgg aacaggtatg ttagttagtt
      601 caatagcacc aattaatgga gctttccaaa gtataagtgg tggtgcagta acaaaaggtt
      661 taagtgatgt tacttttact gcaagttatg gtggaattat aggtttagca atgtttgcgg
      721 gtttagctat tcacctaatg atagcaagat ttactcctat taagacaatc ttcttaacag
      781 gtcacatgct ttattggttc ccattcatat ttgtagcttc aggagttgaa gctggattaa
      841 atggtggagt attaatagct tttgcagcag tattatcagc actctattgg tcaataatgc
      901 cttggttatt aagaaaatat gtgtttgatg ttataggaga tgattctttt acattaggtc
      961 atccatctgg ttgtttagca cttatatcag gatttgttgc taaattagta ggaaataaag
     1021 aaaaatctac agaagatata aacatacctc aaagtttatc attttttaga gaaatatcta
     1081 taagtggtgg aatggcagtg tttttaatgt ttatagttgt tgggatagta ataccaggtg
     1141 cgtttaaaga tagtaatgag tttattggaa cgtatgcaat aaagcaaggt ctttcttttg
     1201 gagcaggtct tataataatg cttcatgggg taagaatgct aataaatcaa ataatgccag
     1261 catttcaagg tatatctgaa aaagttgtgc caaatgcact acctgctttt gactgtccaa
     1321 tattatttaa ttataaacca aatgctgtat taataggatt cttagttgct atgctaacat
     1381 ctacagctat gattttaata tataactact ttaatgtatt taatttgcta cttataccac
     1441 ttgttataac ttcattcttt gagtgtggag cagcagcagt aataggagaa tcacaaggtg
     1501 gtatacgtgg agctataata ggtacagcta tagctgcaat atttatggta gttttagtag
     1561 gaatatctgc tgtaatttac tcaggaacta ttcaaaattg gatactaata tttggaggta
     1621 atgacctttc attatttggt ataatcagta ggtttatagg ttcactattt ggaggaatat
     1681 tatagatatg aaatttaaat acatagatga gataagaaga ttaattgata taatagaaaa
     1741 cgaagaaaaa gtcaatatgg aaaaagcagt acaaatcttt gttgaagcaa tagaaagtaa
     1801 aaatgctata ttttcatttg gagcttcaca tgcaggaata ttaacagaag aattattcta
     1861 tagagcaggt ggctgtgttc ttataaatcc agtatttgca aaatctctaa tgttagatac
     1921 agcgcctata actcacacaa gtaagatgga aagattagaa ggatatggta cagctctagc
     1981 tgataaaact ccaattaaaa aaggagatgt agttatagtt cattcagtat ctggtagaaa
     2041 tccagtaagt atagagtttg ctatgaaagc taaggaaaat aaggcaatag taatatgtat
     2101 aactaattta agttactcaa aaagtgtatc ttcaagacat tcttcaggaa aaaaacttta
     2161 tgaagtatgc gatttagtga tagataatca tggtcaaaag ggagatgcct gtgtagagat
     2221 agatggatta aaccaaaaag ttagtccaac ttctactgta atagcaacta ctgtgatgaa
     2281 ctctattata gctcaagcta ctcaggaatt agttaataaa gggctaaaga atcctccgat
     2341 tttctatagt gccaatattg atggtggaga tgagttaaat aagaagattt ttgatgaata
     2401 taaaagtgta attcattatg aatattaagg ttaaaaaaat atgttaatga actttgaagt
     2461 ttatcaacaa agaatattaa taatatataa taaatgctat catttaaaag ctgtaggtaa
     2521 aaatctacag ctttttatta ttgtagatta aaaagatgcg taattaaatt ttaaattgga
     2581 gaaaataaat tggaaggtat caattataaa tattagaaac gttgtcatag aaaaaaacta
     2641 tattaaaaaa aagtacatag aaaaaactga ttagacaata aatacatgct ttgataatat
     2701 tttaaatgga atgaaaatgt gtagaattat aatgaaaaaa gaaaataaaa atgaaaaaag
     2761 aaaataaaat ggagggaata aaagtgggta tgttaaaaaa attatgttca ctagctatgg
     2821 tagcaattat gactacaaca cttataacag ggtgttcaag tggaaatgga aaagattcaa
     2881 aaaaggatgg cgaaaaagaa aaactagttc tttggatgcc accagtagaa aataatatga
     2941 aggaagtttg ggaccctatt ttagataaat ttgaggaaaa aaataactgt gaagtagatt
     3001 tacagataat tccttgggat aattattctg aaaaatttgc aacagctata agtgctggcg
     3061 aaggtccaga tgtaggatat atgtatgcag aaatgtatcc acagtttata gaaagtggag
     3121 cagtagaaga tttgactaac tatgcaacta aagaggataa agagcaatct atttatataa
     3181 aaacatctga aatgatgggt ggaatgtatg gtatgccatt ccaagcagca aatccagggg
     3241 tattatacta taacaaggat attttagaga aactaggaga aaaacctcct aaaacatggg
     3301 aagattttaa aagaatttgt aaaaaagcaa cgcaagatac tgatggtgat ggaaagatag
     3361 accaatgggg attagctcag ggatggggag ctaaaacttt tggtaactta aactggaact
     3421 ggtatcctta tttatggcaa gctggtggag atatatttaa tgatgattta aaatcggtta
     3481 aatttaatga taagagtggt ttagaagcag ctaatttctt aaaagaatta caagcatatg
     3541 tgcctgaaga ttctttatct aaagatagta atgaaatgat agaaagcgta tttggaccag
     3601 ggaaagcagc atttacaata atgttatctt ctgctgcaac aagtgtattt gatgaatcat
     3661 tcccggattt aaattgggga tttgtaactg gactagaaga taagaaagca gcaacttttg
     3721 gagcagtaga ccatttatct ttaatgtcat ctgctaaaaa taaagaactt gcatacaagt
     3781 taatacaaca tatgttaagt gttgaatcaa tgacagaatt tcataaagca ataccaagag
     3841 caccaataac aaaaggtgaa ccatatcaag gtgatgaaag attcaaagaa atggtggaaa
     3901 atgacaaaaa tgtatataga ccattagtag taggacctca tggagttgaa atatatgaat
     3961 atttatggaa agaacttcaa actatgattt caggagataa aactccaaaa caagcgttag
     4021 atgatgctgc aaaatattca aatgatttat tagcacaata aaagtttaaa gctgtaatat
     4081 gttgtaaagg actttacaga ttaaaattag cattgtattt ataaatacaa tgctaatatt
     4141 tatattggag aggataaaat ggaaaactta gttagagagt ttgaagaaaa ttcaaaaaga
     4201 aaaaaaacaa aattaaatat taaaccatat atgtatatat tgccattggg aataatttta
     4261 gtggcgtttt atgtgatacc aataataatg tcaatatact ttagttttac aaagtataat
     4321 attattagtc cagctacttt tataggttta gaaaattata aaaaattatt tacagatgaa
     4381 acattaaaag tatctattat aaatactatt aaatttactg ttgttgtagt accttgccaa
     4441 actatattat cattgatttt ggctgtttgg attacaggaa aaggaaatag taaaatagct
     4501 tcatttgcta aaggtgctat atttatacca gtattatcat ctatggtttt gataggtatg
     4561 gtatggaggg ctttattgaa tggagaaggt tctattatat atcaggtatt aggtgccttt
     4621 ggaatagaat catctaaact tttaggagat agtaagacag cattacctac acttatgttt
     4681 atatctatgt ggaaaaatat agggtatttt atggtaattt atatttcagc tataatgaat
     4741 ttaccaaaac actgctatga agtagcgaag gttgatgggg ctacaaaact tcaagaattt
     4801 ataaaaataa ctgtaccttt attgaaacca actacaataa tggttgtatt tttagggtcg
     4861 atatggtcat tacaagtatt tgacttaatt tatactgtga caggtggagg tccaggtata
     4921 tctactatga gtatagttat gcatgcattt aacttaaact ttaaaaactt taattctgga
     4981 tatgcaatga ctgtagcaaa cgtattattt ttgttaatag cagtagtttc gattttacaa
     5041 aataagcttg taagacgaga caattcagat ttttagaaag gtaggtataa tatgaaaaca
     5101 gcaagaagat tattaagtga tggtttgctt ttatttatag cgtgtgcaag tttggtacct
     5161 tttatataca tgttgataat atcattgaag ataacatata actcatatag tttggatata
     5221 tctttttcaa cagtaaccct tcaaaactat atagatattt ttactaaaaa aggatttgca
     5281 caatattttt ttaatacagc aatagtatct ttttcaggtg tattattaaa tttagtattt
     5341 agtacattag caggatattc ttttgcgaag atggatttta aaggtagtga taagttattt
     5401 ttatttatga taatgacttt aattatacct tcccaagtta caatgatacc actatatata
     5461 ataatgaaac acttaggatg gataaatagt tatcttgcac ttattatgcc aataccaact
     5521 gcatttggcg tatttataat gagacaagct attttaggag taccaaaaga gttattagaa
     5581 tcagcaaaga tagatggttg ttcggatttt agaattttaa tacaaatagt gttgccttta
     5641 attaaaccag cattaattac actagcaata tttactttta tgggagcatg gaacgagttt
     5701 atgtggcctc ttatagctac aactaaagat acaatgagaa cattaacagt tggattatct
     5761 actcttaaga cattccagat aactaattat ggacagatga tggcaggggc tacaataaca
     5821 tttttacctc catttatttt ctatttgatt ttacagagta aatttgttga aggtgtgtct
     5881 ttgtctggta taaaaggtta aatagtctaa tttaataata tataaagaaa cttatataaa
     5941 tatggaggaa tttaaactat ggaaatttca tatgtactga aagattgcac attcaaacac
     6001 aataaatact cagttgtaga agctgaaact tggaaagata aggatttgga tattgtagta
     6061 gctaaaggtg aaaaatttgc atttcaaatt atgttaaaag caacagaaga atttaattgt
     6121 acaattgata aaagtagtgc tatatcatgg aaaggcctgg gaaatagagt aaggttagca
     6181 ttaaatatgc ctaatagttt agaaaataat tttagtataa atatattagg atatgttcaa
     6241 gatgatacaa aggcatttgt gaatgatgct attttaaggg ataaagatgt gttagtagag
     6301 caatatttgc ctcaaacatt ttggattgaa ggtcaagtac cagaagattt tgaagaaaat
     6361 aaccttgata taggtattga tatatttaaa agctttggat atgaagacga agaaaaagtt
     6421 tgtacaattg atgttcctgt aaaagtaaga aatgttgtgc taaagccttt agatgaaagc
     6481 aagttctttt tagatttatg gcaacatcca agctgtttag ctagaatgta taaagttgag
     6541 ttatggtctg atatacattt tgaaatagtc gataactatt taaaagaatt agcatcttta
     6601 ggagaaaaag ttgcaacagt tatagtttca gattatccat gggcagggca aagttgttat
     6661 aaagtttata aaaatccatc aaacttatat gaatataaca tggtaagtgt atcaaaagga
     6721 ttggatggaa agattaaatg taactttgag agtatggata ggtatataag catagctgat
     6781 aagtataaaa tggctaagga gatagattta tttggtctat taggtaattg gtgtgctggt
     6841 gagtttggaa atcctgtaga aggttataag gaccctataa gagtaagata ttttgatgaa
     6901 aaggataaag tatttaaatt tataaacaat acaaatgatt taaaagaata tataggatta
     6961 gtattaaatc atttaataga gtgtggatta tgggacagag taaggattat agctgatgaa
     7021 ccaaataatc cagaagtagt caaagagtgt atagaattta taaattctac tgtaagcact
     7081 catcaagtta aatataaatc agcaactcac gaccaaaact ttttagacag agctaaagat
     7141 gaaattgatg atatgtcaat aaatttaaaa cttactatac aaaattataa agatatagaa
     7201 agtcttaaga aaaaaatcaa tgacaagggt gggatattga cttggtttgt atgctgtttt
     7261 ccagagaaac caaatagttt tttaagttct ccttttgtag aaaatagaat aataggatgg
     7321 tatacttatt actttggtct tgatggattt ttaagatggg actataattt atggacagaa
     7381 gacccttgga aagattcaag ttacaaattc cctatttgga aagctggaga tatgttcttt
     7441 gtttatcctg gaaaagattt aaagccagtt agaagtgtca gaatggagaa tttaagattt
     7501 ggaatacagg actttgagtt atttacaatg ttagaaaaag aaaagggaag agagtatata
     7561 gaagttgagc ttatgcaaga attattaaat aaaaaagaaa atgctgaaat taaaggtttt
     7621 ggtgacatag aactaggata ttcacttgat aattggggat atgataaagt taaaaaatat
     7681 gtattagagt tgttagacag agtataaaaa atataagagt gtctcaaaat gaacttttta
     7741 gttcatgagg cactcttttt gtatgaaatc aatatagttt cattgtttca acaatgaaaa
     7801 ataggattat ttctattcta agacagccct ttagtttttt agttgtattc aatgttttaa
     7861 aactaactat aaacgctata aagtttataa atgacaataa ttatatataa catgatgtac
     7921 tttaatttgc tataataggg attgaataat attatatgga agataacatt gtttgggggg
     7981 attaatataa aaagaatagg tattattata atgttttttt taagtatatc ttttattgga
     8041 ttttatcttg taataagaga taacagtgat acagttaaga tgcaacgagg gataaatata
     8101 ggtaatgcac tagaatcacc taaggatttt ccgtgggatg taaaaatgtc aaataagttt
     8161 tttgatgata taaaagatgc aggttttgac acagtacgta taccagtaag gttttctgat
     8221 tatacgtcag attctgataa ttttaaaatt gatgaagaat tttttaaaaa gattgataaa
     8281 tatgtagatt atgcattgga taaagactta atagttgtgt tggatttaca ccattttgaa
     8341 gaaattatga aagaaccaag agttcataaa gaaaagtttt taaaaatatg gcaacagata
     8401 gctaataggt atcaaaaata tgataaaaaa ttggtatttg aattattaaa tgaacctaaa
     8461 gaaaatttat attcacagtt actaaacgaa tacattgaag aagcaataaa gataattaga
     8521 aaaactaacc ctaaaagaac tattatagta ggaccatata atttctatca aattgattat
     8581 ttgaatgaat taaatattcc taaagattct aatatagtag tttcctttca ctattacgag
     8641 ccaaatgatt ttgcatttca aggaaatata tatcataagg gatttgagca cttaagcaat
     8701 attacttggg aaggaacaaa cgaacaaatg gattatttaa aaaaaaggtt tgatactgtg
     8761 gaaaattggg caaataaaaa taaggtaaaa atcttcttgg gtgaatttgg aataacaaaa
     8821 gaggcaccag aagcttcaag aagagcatgg ataaaagctg taagagaaga agctgaaaaa
     8881 cgaaactttt catgggctta ttgggagctt gcatctggat ttggtatata caatcaaatt
     8941 gaagggactt gggatagaga tatattaagt gcattaatag aaaagaggtg attttatgaa
     9001 gaaaaattca aaaaagatac ttataacttt aactattatt actaatgtca tatatatatt
     9061 gtggagaatt ttttacacag tacctaaaga agaagggaag tttgccttaa tatgtgccat
     9121 aatacttctt tttgtagaga taatgggcat gatggaaatg tttgtgcatt attatggtat
     9181 gtcaaatatt gagtaccctg aaaaaccaat cataagtgaa gaactttatc cacatgtaga
     9241 tgtattcatt gcaacatata atgaatctgt tgatttggtg agaaaaactg taaatgggtg
     9301 tattcatatg cagtatccag ataagaaaaa ggtacatata tacatatgtg atgatggaaa
     9361 tcgtgaagaa atgtgtattc tagcagaaaa aatgggtgta aattacataa ctagaactga
     9421 aagagaagga gcaaaagctg gaaatttaaa taatgcaatg caacatacaa attccccttt
     9481 gattgctaca tttgatgcag atatgatacc aatgcatgac tttttaattg ctacagtacc
     9541 atactttttg aaaaatgagc aagctaaaaa agatggagaa aaagaggagt atgaaaaggt
     9601 tggttttgtg caaactccac agagttttta taatccagac ttgtttcaat ttaatctgca
     9661 ctctgaagga aggattccaa atgagcaaga ttatttttac agagacattc aattggctag
     9721 aaataggaca aattctgtaa tttatggtgg tagtaataca gttatttcaa gggaagcact
     9781 tgaagaagtt gatggatttt atacttattc tattacagaa gattttgcaa caggtatctt
     9841 aattcaaagt aaggggtata gatgttatgc tattccagaa gtacatgcat caggtttatc
     9901 tcctacagat ttaaaaagtc ttattaagca acgtgaaaga tgggcacgtg gatgtataca
     9961 aactggtaga cgtctaaata ttttgtttag gagaggttta ggtttttggc agaaaataag
    10021 ttatatttct tcaattactt attggtatgc aagtataaaa cgctttgtat atataatggc
    10081 acctatttta ttttctgtgt ttaatgtgat tgtagtaaaa tgtacgttac ttcaagtatt
    10141 ggtattttgg ttgccaatgt atattttaag tagtttatct cttaaaatat tttctcaaaa
    10201 tataagaaat actagatgga ccaatatata tgaaactata atgtttcagt ctttaatgcc
    10261 agcagtaata cttgaaacgt ttgcaatatc taaaaataaa ttttcagtaa caaataagag
    10321 taaattagaa gaaaatagaa tgtataagtt tttacaggga ataccttatt ttatttacat
    10381 ggtcttatct atcataggaa ttttaaaaat gtttgtagca atatttaaaa tgagttcaat
    10441 gacatattca gttgtattat tttggttgat tggaaacctt tttaaccttg ttatggctac
    10501 attatttata tcagggagac agcagttaag aaagtctgag cgttatattg ctgaaattga
    10561 ttttaagtta aagcaaaatt cttatgttct ttcttcaaaa acaattgata tatcagaaaa
    10621 tgggtttgca tttttgctag aaaatccaga atatatttcc ccagaagaag agtttgaggt
    10681 agagtttaga gaaaaatctg gaaatgaaat gtatatagct aatatgaaag caaagattgt
    10741 taatgttgtg gaagtaaatt caaagtggaa atatgcagct tatattacac atattgaaga
    10801 tagtgaaata gataattgga tgtgtattgt tcacgataga atacctactt taccaatgac
    10861 aatatctaat caactaggtt tctttgatga tttgcaaatt aatgtaaaaa aacgtattga
    10921 aaaaactaga acattatcac gaagaagtcc aagaatcaat atgaattttc agatggatat
    10981 aaaaaataca ggtaaattaa gaatagtgaa ttttaattat caatatgtat tattaaattt
    11041 tgagaataaa agtatttatc ctaaagaaat agcattggaa attaatgaaa atattgtgtt
    11101 agaatgtgat ttgtgtgagg gtaaaattga tgaaagaggt atcttatata aagtaaataa
    11161 cattgacagc ataatgcaaa atttcttttt aagagatgaa atgatggatt ggatattaca
    11221 aaataagaaa attcttgatt caaagcctag tgaaaagaag gaaaaaagta tagatgagtt
    11281 tgaacccatg gaatatattt aggagagatg aaatgaagac tttaaaagtg tttttttgtt
    11341 ctacaaaata tcttattttg gtgtttattt tttttataaa tactactttt ataagttcag
    11401 caacaagtga taaaatttta gatttatcct ttaaaaagat agagactgac ttaagttcta
    11461 agattacata tgaggataca ggtgtaaaaa tagaaacgga tagttctaaa agcgataagg
    11521 aacgttattt atatatttac caaaatataa aagaaaattg gagcatgtat aataattttt
    11581 atattgaaat tcaaaataaa aataaaagtt ctcagagaat aaatttaagc atacaaagta
    11641 aaaatatgct tgaatttaga ttaaaagaag gtagtgaagt atttttagaa ggtaaaaata
    11701 taatatattc agataaaata aaagaaggat gcatagaagt accaggtgaa tttgaaggca
    11761 aaatttatgt gaactttaat agccttataa atgaggaaag taatgttgtg ctggactcaa
    11821 atatgctttc aaacattgtt agttggggaa ttacgtttat tccatctgat gaagaacata
    11881 atattgttat tataaaaaag atatctttat tgtctgaaga gaaattaaga tttttaaata
    11941 atattaaaat aattggcgat gaagaagtac aaataccagt attgggtcaa agtataagtc
    12001 agtatgaggt attaggtctt aaaagtgatt ctaaaattaa gtactctctt atgggaaaac
    12061 aagataatgt gagtatatct caaaacggta aattaacatt aagtaataaa gccaaacctg
    12121 gacaaattat tttacaagtt aatgttgatg ataagtttaa aattggaaag aaaataacat
    12181 taactgaatc ttggagtatt aataaaaaag ataaggatgg tgttccatat acattagtat
    12241 ctcctgagca atcaccaaca gtacaagata tgaaaaaaat aaattttatg aataatatca
    12301 taacgtttgt tcgaatttta tttgtatctc tagtaataat atgctttgga atatatttat
    12361 attggaaaaa atgttcaaaa actaagtaaa gagaggaggt tagattgtgt tattttcaag
    12421 tttaattttt ttattttatt ttttacctat aactttggtt ttatattatg tatttaggtt
    12481 taaccgaacg atacagaaca tgatattgct tgctgttagt ttattttttt atgcttgggg
    12541 agagccaaaa tttgttgtta tcatgatagt ttccataata atgaactata tatttggttt
    12601 actggtagat agatataggg aaagtaaaat aaaagtaaaa gtttttttag ttttgatgtg
    12661 tgcatacaat ataggtgttt tatttatatt taaatatcta gcttttgcgc taagaaatat
    12721 tagtgaactt attagtactg aattgactat acctaatatt attttaccta taggaatttc
    12781 attttttaca tttcaaggaa tgtcttatgt tatagatgta tatcgtagac atggagaagt
    12841 ccaaaagaat cctttttatg tgggactgta tatagcattt ttcccacaat taatagcagg
    12901 tcctatagtt agatatgaga gtgtggcaga acaaattctc aatagaaaag aaacttggaa
    12961 taaattttct attggtactt gcaggttcat aacaggtcta ggtaaaaaag tattaatttc
    13021 aaataacatg gctatagtag cagactatat ttacactatg aatagtcaag gagaaatagc
    13081 tgcatcactt gcatggcttg gttcaatagc ctatactctg caaatattct ttgatttttc
    13141 tgcttattca gatatggcta taggcttagg tcttatgttt ggttttaaat ttgaagagaa
    13201 ctttaattat ccatatatat caaaatcaat tagtgagttt tggagaagat ggcacatttc
    13261 tttgggaatg tggtttaaga gctatatata ctttccgctt ggaggttcta gagtagcaaa
    13321 taaagatatt atgattagaa atatgtttat agtgtggtta ttcactggaa tatggcatgg
    13381 agcagaatgg acatttgtaa tttgggggat tttaaacttt gttttcctaa ttatagagcg
    13441 atttataatg tttgaaaaga ttgaaaatca caattttata aaacatattt atgctttatt
    13501 agtagttaat tttggatggg tattgtttag gtcacctaat ttaaaagaag catataatta
    13561 ttttaaagct atgtttggag gcaatggagc tatatggagt gattatacat atatgttttt
    13621 aaaagaatac tgggttttct ttatatttgc atttattttt agtgtaccta ttgcaaagaa
    13681 aatcaataag tttgttgttg aacaagctaa atatagtatg atatttaacg tattttatcc
    13741 aatctcagct attttattgt tttttatttc tgtgacatat ttagtaactg gaagctataa
    13801 tccatttatt tattttaatt tttagttggg aggaaaagta tgaatagatt ttttaaagta
    13861 agattaataa ctgcaattat gttcttaatt attttattcg ctttctctat ctttaatgtt
    13921 tgttattctg gaaaagatac gatacaggaa ataaaaaatt caatagctga aaaaagtagt
    13981 ttaaaagata caatatcatc tattgataat acagtgaatg acaaagtaat atacaaaaat
    14041 acgttcattg aaacttatgg ctatttacaa aaattaatgg gtaaaaatga gttttcaaaa
    14101 tttagtgttg taaaagatac ttctggaaag atgcattata catattttgc taaagctcca
    14161 aatccagttg gtgtgatagc agatagggta agaaaatttt ctgatgaaat ggaaaagcaa
    14221 aacactaaat tggtttacct aatgactcca gataagtata taaaaggagt gacaaaattt
    14281 ccaaaaggaa taccttattc ttatagtaat gagacagcag ataatttttt aaatcaacta
    14341 aaaaagtata atgtggacta tattgatttt agagaaaata ttttaaagag tggtattcca
    14401 aaagatgatt tattttttaa aacagaccat cactggaaag tagaaacttc tttttgggca
    14461 tttggagaat tagttgagca acttaataaa aaatacaata tgaatttaga tgaaaatcat
    14521 tattatagag ataaggacaa ttataattca attgtatatc ctaagtcatt tcttggttct
    14581 atgggaagaa agactggtat cttatatggt ggtatagatg attttacatt aatttatcct
    14641 aaatttaaga ctaattatac ttattataca gattctaaat ctcaaaaatt tgaattaaaa
    14701 ggaaggtttg aagagagttt aatattatca tatcctttta atgcagacct tgatttaatg
    14761 gatggtcaat cagataagta ttttacatat ttattgggga acagaccatt agttaaaata
    14821 aaaaatatag aaaatccaga tggattaaaa gtgctgtttg ttaaagattc tctaattgta
    14881 ccaacagcag catttttttc ctctgtttgt tcatctatag atatgataga ccctagatat
    14941 tatgatggag atatactaga atatgcaaaa tcccatgact atgactttgt ttttatatct
    15001 gtatatcccc aaaatcttac aaaagaattt tttccgtttt gtgagtaaat ttctaaaaaa
    15061 gttttctgat aaaataaatg gctaactggt aaaaagttag ccatttattt tgagtgttat
    15121 tctaagaaat atttttttta ctaaatactt ctttatctat ttttccaagt gattttccta
    15181 cagtaattga tgataccata gcaccattaa catttatcat agtacgtccc atatctagta
    15241 tagggtctat tgcaagtata ccaccaacta atggaaaata agaaccaaga ccaactccag
    15301 agataacaac tgaaacggcc attgtagcag ttcctggaag accagctatt ccaaacgaac
    15361 taattgttat aacaattaac aacataacat aaaagctcat atccatgttt actccagcca
    15421 tattggcaag tgttacagcc attaaagcag gatatatacc tgcacaacca ttcataccca
    15481 tatttgcacc taaacttgct gtaaagcttg atacaccctc atcaactccg tgattttgta
    15541 ctagactttc tatcgttaca ggcaatgttc ctaaactaga acgtgaagta aatgccagaa
    15601 gtaaagcttc agttgaattt tttatataag taatgggatt tagaccattt aaagttataa
    15661 aaattaaatg tataataaat aatattgcaa ctgatatata aagagctaat ataaactgta
    15721 aaacagatac tattgaacta ataccttgtg aagttattgt atttgcaagc agagcaacca
    15781 cagcataagg cataaattta ataacagtca tagacacact tacaattatt ttgtaagatg
    15841 cttctataaa atctataaat ggttttattg tctcaaaatg ttttttactt aatctcttta
    15901 ttgaggtagc tataaatgta gcaaatatta ttgtagctac aatatttcca tttgccatag
    15961 ccattacagg attagatggt agtaatcctc ttaaagtatc cacaagagag tttatttctt
    16021 taagttcttg attttcaact aaagtaggca tattagctcc tacacctaac ttcattatat
    16081 ttgcaacgat aattccaaca attgcagcta tagcagtagt agcaagaagc atacctaaag
    16141 atttaaatgt cagagttcca agattgttat ctttcatatt tataattact tttataatgg
    16201 ataagaaaac taaaggtact actaacattt ttaataagtc cataaatcca gaaccaaata
    16261 ggctatacca cttacttact tcttgtagcc aagtgacttg agttgtatca ttaggaaaac
    16321 cagcaaaagc ttgtattatg attcccaata tgagtcctag tactgtagca tatattgttc
    16381 tcaatgaaaa ttttattttt ttcttttcaa attgtctaac aataaagaac gtacctagaa
    16441 gtaatattat gaaaaaaatt gttttaaaat ctgtaatcat aagaaattgt gataaaaatg
    16501 aactttccaa tatttttctc cttttattta aaaataaatt tttctaagtt taaatgatat
    16561 caatatatta aaaaaatgtc aatattatat cacaatttac ttaaatagag taaaacaagt
    16621 tgattttgaa aaatgtgatt aagtacagaa aaatagggta taataaatgt ttaaagaatt
    16681 tgaattgtgg taagaaaata aaaaatagct tttataagat ttgatttcaa attaaaatat
    16741 gttaaataaa taactaaaaa ttattataaa aaatgttttc atagaatata tatcaaatga
    16801 aaagcttaaa ataagtgaag aaattaacta gacatcaaag gagagataaa atgagagtaa
    16861 taataattgg tggtgttgca gctggtatga gtgctgcagc aaaattaaaa agaataaaac
    16921 ctgagtatga agttgttgtt tatgaaaaaa ctgaaatagt atcttttggt gcttgtggat
    16981 taccatactt tgttggtgga ttttttaatg atgctgatga attattagca agaacaccag
    17041 agaaacttag agaagctgga attgatttaa atatatttag agaagtcgtt gaggttgata
    17101 gtgaatctaa gaaaataaaa gtaaaaaaca taaaaacaga tgaaatatat gaagattact
    17161 atgataaatt gatgatagca actggagcaa gaagtattat gcctcctata aaaaacataa
    17221 aattgaagaa tgtttctaca ttaaaaagtt tatatgatgg agaatatcta aaaaaacttt
    17281 taagtaatga agataataaa agagtgacaa taataggagc tggttttata gggttagaag
    17341 cagttgaggc atgtaagaaa ttaggtaaag atgtagatgt aattcagtta gaagatagaa
    17401 tattgccaca agtatttgat aaggaaatga cggatgtatt agaagaagaa ataaatagac
    17461 ataatgttaa tttgcactta gatgaaatgg ttgtagaact ttgtggagaa gataaagtag
    17521 aaaaagttat aacaaacaaa ggggaaatag atacagatgt agtaataatt gctactggcg
    17581 tgagacctaa taccgagttt ttgtcaaata ctaatataaa aatgctaaaa aatggagcta
    17641 tagtagttga tgagtatgga agaacttctg tagaagatat atactctgct ggagattgtg
    17701 caactataaa gaatatagta agtaatgaaa atgtatatgt tcctttagct actggagcta
    17761 ataaattggg taggatagta ggagaaaacc tagcaggaag agaagtatct tatcaaggtt
    17821 cactatcttc aagctgtata aaaattatgg atatggaggc agcatcaact ggaattacag
    17881 aaaagcaagc taaagattta ggcataaatg tcaaatctaa atttatttct gattataatc
    17941 aaactcatta ttatccagga agaaataaaa tatatgtaaa gcttatttat gatgcagata
    18001 caaaagttat tttaggcgga caagtggctg ggtttaagga tgctgtccaa agagcaaatg
    18061 tattggcagc tgctatcttt ggaaaaatga ccacaaatca acttggaatg ttagatttat
    18121 gttatgctcc accatttgca agaacatggg atgttttaaa tgtagctgga aatgtatcta
    18181 aataatattt agattatagc taatatagtt gacaagcaat taagggaatg aatttaccta
    18241 aactattttt atcatggtaa aattcattcc taaattttta ttccaaattt ttattccaaa
    18301 tttttagaaa taaggattcc attaaattat tcatcaaaat ttaaacgcaa gcttaatcta
    18361 tcttctccaa ggatagtatt ttcaaaaaca ttagtagcat tttctaaata catactaggt
    18421 atgtctaaag aaggactaaa atgagtcagt aaaagttgtt tgacatttcc aagttttgca
    18481 agattagcag cttctctaaa agtcatatgt ttgtttctaa cagcttttga tatatctaaa
    18541 tcatcaccat acatggcttc acatataaat aaatcactat cttttatgaa atctggtatt
    18601 gattctatag gtcttgtatc ggttgtaaga cttatcttaa ctccctttct caattctcct
    18661 aagaccatat ctggagtgta ttgttttgaa tctaaaacta tattttgacc ttcttggagt
    18721 ttgttccata atattttagg aacttcgttt ttagttgcct tatctatatc aaatttaggg
    18781 tttcttctaa aattaaaact gtatcctaaa cactctatag agtgttctaa actgattgtt
    18841 gaaatttcta aatttcttaa aactttatta tctaaagaaa aattgccttg agggttttct
    18901 ataattttta aagtgtatgg tacatattct actaaatttc tcatagaacg tatacaatcg
    18961 actattccaa ctggaccaac tatagttaaa tcacttgtac gaccactatt tccaattgtt
    19021 gataaaagtc ctaaaagtcc aaatatatgg tcaccatgta aatgggttat acaaatcaag
    19081 tctatatctt taaagccaca tttttttagc ttcatagata cctgagtacc ttcaccacag
    19141 tcaattagta tttttctacc tttatagttt ataaatacag aggatagaaa tctgtttggc
    19201 ataggtacat ttccaccaca tccaagtaaa gttaaatcta tcattttttc ccctttctaa
    19261 aattaacaca aatctgttgt ttgtttttat tatgatatcc tattataatt attttaacat
    19321 taaatataac aataaatgtg tatttgagtc aagaaatatt gtcaaataaa gtttttatat
    19381 agaaatgtat aaaaatttgg aaaacaaaaa gtgaaaatta tatttaggag catttaaagg
    19441 aggaaaattt aatgaaagta ttaaagaaaa ttactatttt gtcattaatt acattaacct
    19501 tagttggttg tagtaacgga gaagataaaa aagtggttga aggttctaag aaaattcaaa
    19561 attctaaaaa agatgaacag cctataatag tacataaaga tgcaaatata ttgaaagata
    19621 ggtatgagcc accaaaagga tttaaaagag ttgatgtaga aaaaggtagt tttgaatcat
    19681 ttcttaggaa tactaagcta aaaaattatg gagagaaagt aaagtattat gatggaagaa
    19741 ctaaggaatc aaaaggtatt tatgatagtg tatttgatgt tgatattggc aatagagatt
    19801 tgcatcaatg tgcagatgca attatgctta tgagagcaga atacttgtat cagaataaac
    19861 tatatgatga aataagtttt gattttgttg atggttttaa ggcgaagtat tcaaaatggg
    19921 cacaaggata tagaatttca gtaaaagata gtggttcaag ctggtataaa gcaactgaat
    19981 attcaacatc ttatgagagt tttagaaagt ttatggatat agtgtttgca tattcaggaa
    20041 cgttatctct tgaaaaagaa ttggagcctg taaaagttga ggatatgaaa ataggagatg
    20101 tgtttatagt tggtggaagt ccaggacatg caagtataat tatggatatg gcagaaaatg
    20161 aaaagactgg tgaaaaggta tttatgatag cccaaagcta tatgcctgca caacaaacgc
    20221 aacttcttat taatcgtaaa aatccaaatt tgagtccttg gtatagttta gattttgaag
    20281 gtgatttgac aatacctcaa tggactttta aaagagacca gttgaaaaga ttttaaaata
    20341 ataattttat ataataaaag aaaaatatag atgtgaaaaa atgtaattag attaaaacta
    20401 attggatatg gacaaaatta aattgataga taaatattaa aaattacact aattaatctt
    20461 actatagttt aatatttatc taaaaagttt tatgtaaaat ataaatttta tattaaagct
    20521 aaaactaatt tgaggaggct aatttatatt gaagattaga aggtatttaa ttttggtaat
    20581 tataattcta attacaacaa gtcagagttt tatttcttat gggctagagc gatttgaaga
    20641 aataaccatt tttcacacta atgatataca tggaagatat gctgaaggtg atgaccatat
    20701 acaaatagga aatctagcca cattgaaaaa agaaactcca aactcaattt tagtagatgc
    20761 aggagattgt ttgcatggac ttccaatagt aaatatggat agagggaaaa gtgcaattga
    20821 attaattaaa tgtgctggat atgactatat tactcctgga aatcatgact ttaattatgg
    20881 aaaagataga ctgtttgagt tatctaaaag tgctaattta ggagagaata ctttaaaatt
    20941 tttatcatca aatatttttg aaaatggaaa aaaagttttt gatagtaatg atataaaaga
    21001 aatagatgga ataaaaatag gattttttgg actctcaacc caggaaacaa agagcaaaac
    21061 tggatttaaa aatgtggaag gattagagtt taaaaatcct atagaaagtg caacagaaca
    21121 agtaaatgaa ttaaaaggaa agggtgccaa tgtaatagtt gcaatatgtc atattggtac
    21181 aaatagttta agtaagccaa atagtataga tatagcaaat gaggttcaag gaattgattt
    21241 gattattgat ggacacagcc acactaagtt tgaaaatggt aaacaagtgg gtgatacatt
    21301 gattgtaagt gcaggacaat atttagaaaa tattggcgag ataaaactaa ctttggatac
    21361 taatgatgta gaaaatataa aaatagaaaa taaatcagtt agattaattg gaaaagaaga
    21421 agcattaaag tataagcttg actccgctgt aagtaaaaag gttgatgaaa taaaagaaca
    21481 acaagaaaaa atattagata aagttatagg ggtaactaca aatactctag atggttcata
    21541 tgaaaatgta aggacaaaag aaactaattt gggtaattta ataagtgaca ttttactaga
    21601 taaaactaag gctgatattt ctttatttaa tggagggaat attcgagata cgatagaaaa
    21661 aggcaatata acaagaagag atattgtaga tgtatttcct tttagcaata ctatagttac
    21721 caaagaactt acaggagcac agattaaaga tgtattggag catggagtaa aactttatcc
    21781 agaaaaaagt tcagcctttt tgcaagtggg aggaatttca tattacttta atcctaaaca
    21841 aaaagaaggc gaaaaaataa caaatattca aaaagaagga aagccattag atttaaataa
    21901 aaagtatgta gttgcaacga atgattatat agcatcaggt ggagatgaat ttccttgttt
    21961 ttcaaaagag ccagtactaa aggaatttgg aaatttagag agtgcagtca ttgaatatat
    22021 agagtacaaa aaagaaatat caaaaaatgt agatggaaga attggtatta aatctaaaga
    22081 tgagttaata agcaagaatc atgagagtga tttgatatta agtgaaaatg aaaaaaatat
    22141 caatgataat gaagagaatc tatctaataa tataaaaagc tctgatagtg ataaaaataa
    22201 aagcttagat aaaacaagtg ctagagaaag ttctaatcta ggaatatcta aaagagaagc
    22261 taaagaaaaa tctcctaaaa caggagattt aggtttttca aatagtataa ttatatttat
    22321 agtttcaagt acattgatat gtttattgaa ttttaatcaa aaagagttaa aggataaaaa
    22381 gtcaaaataa aaattaatga gcaaaaatta gtagatagta atttaatttt agataatagt
    22441 aaacagcaaa ggaaattagt tatataaata ctaatttcct ttgttttatg ttttaacatg
    22501 attactttta aataaaattg tattttatga aaaataatta cactaaatgg catagtatta
    22561 tggggatttt tagtttttat tcaagtaaat gaaatcatat taacaacttc tgatatattt
    22621 acaaattgat aaaaaaatga ttttattagt atgatataat ttagctagta tatatgatga
    22681 tggaggatat agggatgaat aatatattac ttttggaaga tgacaaatct ttaaatagag
    22741 gaattagttt taaattaaaa aaagaaggat acaatgtttt tagtgcattt ggtatagaag
    22801 aagcaaaaaa tattttcgca aaagaagaga tatgcttaat tatttccgat ataggtctac
    22861 ctgatggtag tggttttgac ttttgtgagg agattagaaa gaaaagtgat gtttacataa
    22921 taatgttgac agctcttgat gaagaggtgg atattgtcac aggatatgat ttaggtgcag
    22981 atgattatat cacaaagcct tttagcttga tggtattaat atcaaaagtg aatgcgctta
    23041 tgaaaagagt aaatacagta aaaaattata ctctattagt ttgtgatgat ttattctttt
    23101 attatataga aaataaatta attataagaa cagatgataa ggaagaagag ataattttaa
    23161 gtaagacaga gacaaaacta ttaaaatatt tgatggaaaa ttctatgcag acattgacta
    23221 aagagcaact gttagaatct ttatgggata gtagtggtaa ttttgtagat gataatacga
    23281 ttgcagtaaa tataagaaga cttagacaaa aggttgaaaa aaatccatct gaacctaaat
    23341 atataaaaac agtaagaggg gttggatata tgtggggaga aaggagtata aaaaaatgct
    23401 aaaaaatatg aacctcaaag atggtttaag tgtgaaagat gattatataa tgagaagagt
    23461 tattgtatat tctgttttat ctgtactaat agtaaccctt gtatttatac tttttgaata
    23521 tagcagatta cataaattgt atgaacatca aataaaaaac actcaaaata ttgctggaat
    23581 attgattgaa aaatatccta atgatgaaat agatatagta aattctattt ataattctga
    23641 ttatagtaag gtgtctactg gagaaaaggc atttaagaaa tttggctatg gattggaaaa
    23701 taaaatgtca aatgataaaa attttagctt atacttaaaa tcttttttta aggaatcatt
    23761 ttttattttt ttaatgatgt ttatagtagt tataggtata atatattatt ttataagata
    23821 cataaataaa agattgagta aaatttattt tatagtagat aagatgtcac aagaaaacta
    23881 cttgaaggac actactgagt cagaagaaac tggttatcta gtagaatata atgaatactt
    23941 taaagaaggc atatttagta agataaataa ctgtctatat gagcttaata gaagtttaaa
    24001 gataaagttt attaaattag aaaaagaaaa agaaagtgta aaatcattag taacagatat
    24061 ttcccatcaa ttaaaaactc ctttagcatc cttaaaatta tacaatacat tacttataga
    24121 agaagaatta gaagaagatg aagccaacga gttcttatta accaataagg cttctataaa
    24181 taaattagaa aatttaataa attctttagt gaacatatca aggttagaaa ttagcatgat
    24241 aaacataaaa aaagaagata atgatataaa aaatactatt ctaaatgcag taaaaagtgt
    24301 tacccctaag gctaagagca aaagtataac attaaattta aatgaattta acagtagaat
    24361 tataccacat gataaaaagt ggactgagga gagtattttt aatgtattag acaatgctgt
    24421 aaagtataca caggtaaatg gagaaataaa tatatctgta gaagaaactg ctaatttctt
    24481 taaaattata atagaggata atggcatagg gattgaaaaa aatgagttta ataatatatt
    24541 taaacgtttt tatagaggtt ctgctgatga aattgaatct gtagaaggta gtggggtagg
    24601 attgtattta agtagaaaga ttttagaaga acaaggtgga aatattatag tttcttcaaa
    24661 agtaggaata gggagcaagt tttctttgtt tcttacaact atgtaatatt aaatgaaagg
    24721 aaaatgtaag cctctacatt tattatataa gtataaacag ctccagaaat aaaaaattaa
    24781 taaaatatag agtaatataa cttagaatga gaggataatt ttatgaaaat actatatact
    24841 gaaaatttat caaagcatta tggaaaagga gaaagcttag taagagcttt ggacaatgtt
    24901 gacttagaaa taaatgaagg tgaatttgtt gcaataatag gaaaatcagg ttctggaaaa
    24961 agtacacttt tgcatatgat tggaggtctt gatataccta catctgggaa ggtgtatata
    25021 gataataaaa atatatttac attaaaagaa gaagaacttg ctgtatttag aagaagaaaa
    25081 atagggttta tatttcaaag ctataattta attccatctc ttaatgtatg ggaaaatgta
    25141 gtgttgccaa tcggtttaga tggtagagaa gtagatgaat cttttataaa agaactttta
    25201 aaatcattag gacttgaaaa taaacacgac gttttaccaa atacattatc aggtggtcaa
    25261 caacaaaggg tggcaatagc aagagcatta gctacaagac cagctataat acttgctgat
    25321 gaaccaactg gaaacctaga ttctaaaacg tctgatgagg ttatgagtat attaaaatct
    25381 atgtctaaga agtacagtca aactctagtt atgataactc atgatgacag tatagcccaa
    25441 atggctgata gagttatatt catagaagat ggcagggtgt caaaggttgg tgataaaaat
    25501 gattaatact actaaaatag caaaaagtaa tttaaagcaa aataaatcaa aaagtattct
    25561 aataataatt actataatac tttcaacctt aatgctttct tctattggaa tttatattgt
    25621 tgatgcagga gcatatcaaa aagaaaatac tataaagtat tcaggcaatt atcaaggtat
    25681 attagcaaat gtagatgaaa aacaggctga tatattgagt aatcatgcag atgttgaatt
    25741 aactggtgaa atgaatggag taggtgttga aaaactggaa gatgattcaa atatttctct
    25801 agcatacatg aatgaagatg ctttgaaatt aaatagtttt gaatttatca aaggaaaatt
    25861 gccatcaaaa gagaatgaaa ttgtgttaga tagtggagct ttaaaggcac ttggttataa
    25921 aaataaagat ttaggtgaaa agataaaaat atcttatgat gactataaaa atgataaaaa
    25981 aattgaaaaa gagttcatta taagtggaat cttaaaaact agcgaaatat ctgaagcagg
    26041 taaatattat tatgctatta tatcagaatc atatatgaga aatactagag atatgtcaca
    26101 agaagatttt aatatttatg tgaaatttaa tgataaaagt aatttatcaa tagagcaagc
    26161 aaaagaaaaa ttagataaaa ttgctaatga tataggactg gatactatta atactgctgt
    26221 aaatgaaaat tatataaatg ctttaaaacc agatatggaa acgattatgg gtggagtttt
    26281 tgtagggtta gtaattgtat tatctagtat tttagtaata tacaatatat tttatatttc
    26341 aatagttaca aaggttcaag aatttggaaa acttagagca attggtgcaa ctaagaaaca
    26401 aataaaaaat atagtgttta aagaagggtt catattagcc ggaatagcta taccaatagg
    26461 aataatttta ggctatgtac ttgcaaatat tataataaaa tcatttatgg atatagatgt
    26521 aaaatcatca cgattaccag ttatattatc ggttgtggta ataagcttta tatctgttgt
    26581 tttatcactt ttaaaaccaa tgaaagtagc atcaaaagta tccattgttg acgcagtaag
    26641 atatacagga aataaaataa gtaataagag taagagaaaa ggatataaaa atataaatct
    26701 aaagagatta tcacatgcca atttagaaag aaataaaaaa cgtacttaca tgacattggc
    26761 atcacttata cttagtggaa ctatatttat aacagtatca actgccttag aaagttttga
    26821 tgctgagaaa atggcaagag aacactttcc ttatgatata gaagttagac tatctggtta
    26881 tgaaatgaac agtgataaaa atcctaaaga taatttgaat attttacaaa tggataatcc
    26941 tctaagtaaa gattttttta atcaaataaa gaacatggaa ggaattaaaa gaatagaatc
    27001 tgcaagaagt gtaaaaattg gtatggagga ctatgatgtt gaatttaagt atgacctttt
    27061 acaaagtata aatgaaaatg atgtaaaatc attaaacaag aatataatag atggaaaaat
    27121 aaatcttgaa agacttcaaa ctggagatga aatagtaatt actcatgttg atacagcaaa
    27181 agaaatggga gtaaaagcag gagataaaat aagattaact ttatatgatg gagataaaaa
    27241 gataaaaaaa gaatttaaag ttcaagcaat agctatgggg gttccaagtt ttggtatagg
    27301 gaaagatttt atagatagaa ctttgaaata cgattcaact agtagcttgg gaatatatac
    27361 agaagaagga aagtatcaag aaatcaaaga tagtatcaag aagattgcta aaaataatgg
    27421 atttttagag actgatttta tagatagtag aattgagtca aataaggcta ctatttcatt
    27481 tataaagata atgggataca cgctaacagg cataataggt gtgattggat ttatgaatct
    27541 tgtcaacaca atgataacta gcatagttac tagaaaaaaa gaacttggta tgcttcaagc
    27601 tattggtctt actaataaac aattagtgaa aatgcttaat tcagaggcaa tatattacac
    27661 ttctggaatg atgataggaa gtattctatt tggaggtata ttagggtata ttgctgttat
    27721 atttctaaaa aagactggat tatcttatgc aacatattct ttgccaatag taccaatctt
    27781 gttgatgatt gtgtgtattc ttatagctca atttataaca acttatttga taggacgaag
    27841 ttttaataaa gaatctctta ttgatagagt aagatacagt gaataaaatg caaatattta
    27901 tggttagttt aactagcaaa aaacatataa aaaaatatag ttaaagagat tcataattaa
    27961 ataggttaaa gcatagtaca gagcaaacaa tttaaacaga tgtttgctct gtattttatt
    28021 atgtaatcaa taatatatct aatatactga tattattcat gttagaaaat gtaccggtac
    28081 aattctaaaa aagtataaaa ttgtaccata taaaatgaaa attttgtata ataatcgtat
    28141 agaaaataaa taggagctga tatatatgaa taagaagatt aattatgcac caggaccaac
    28201 tgaaactagg gaaaatgtaa gattagcaag agcagaaaaa acaacaaatc cagatataga
    28261 tattgatttt gttgaatttt ataaaaagac atgcgagaag tttggtaata taattggaac
    28321 aaaaaacgat gtttacatat tgagtggtga aggaatatta ggtcttgaag cagcatgtgc
    28381 atcacttaca gaaaaaggag atagagtact tgtaattgac aatggtatat atggagaagg
    28441 ttttaaagat tttgtaacaa tgtatggtgg ggagtatgtg cttttttcaa gtgagtatac
    28501 taaaagtata gatattgatg aattgaaagc atttttagat gaggatagta attttaaata
    28561 tgcaacagta gtgcattgtg atactccaac tggcgtatta aatgatgtaa gcaaaatatg
    28621 tccattactt aaaaaatatg gaatattaac tgtagttgat tctgtagcag gtatggtagg
    28681 agaaagatta agtgtagatg aatctaaaat agatataata ttaggtggtt cacaaaaagc
    28741 tatttctgca ccagcaggac ttactatagt cggaataagt caagatgcaa aaaattgtat
    28801 aaaaaataga aaaactgatg taataggttt ttattgtaat ttaaatatat gggaaggcta
    28861 ttatgagaaa aaatacttcc cttatacaat gccaataagt gacataatgg ggcttgataa
    28921 agcacttgat aatatattag aagaaggaat agaaaatgta ttaaatagac atgaaaagat
    28981 agcttatagt gttagaaaat ctattgagga atatggtcta gaactatttt tagaagaagg
    29041 atattctaat acagtcacag ctataaaaat tcctgaaagt ataggagctt tagaacttac
    29101 tgattatatg cttaaaaatt ataatacact tgttgcaaca tcactaaatc aatatatgga
    29161 tactatttta agaataggtc atatgggaga gaatgcaaat ctaaataaaa tagaacatgt
    29221 actaaatgtt ttggataaaa gtttaagtgc attaggattc aaaggaaatg gaaatttgtt
    29281 aaatttattt aataagtatt atttttaata gataggggga tatagtatgg aagttacagc
    29341 taagcaaaaa tttacaacga aagacatggt ggaaacctca ctattaatag cattagtatt
    29401 tattgcaact aaatttataa acataagatt accaatatct ataaatggtg ggcttgtgca
    29461 tttaggaact gcaatgttgt tcatatcagc aatagtattt ggaggtaaaa aaggtgcttt
    29521 atcaggggct attggtatgt cactttttga tttgatatct gggtggactt tatgggcacc
    29581 gtttaccttt atagttagag gagttatggg ttatttactt ggaaagattg catgggcaaa
    29641 tggtaataat gggaataatt ttttaatcaa tgtaatagga atatgtgttt catcaatttg
    29701 gatgctattt ggatattatg taacagaagt tatactttat ggtaatttta tagtacctct
    29761 tacttcaata ccaggtaatt taatgcaagt attgataggt cttataatag cgcttcctat
    29821 ttctaaggta ttgaaaaaat gtataaaata aatataaagt gaactaaaat ttatgatagc
    29881 ataaattata ctgtataata ttaggatgga gtacataatt aaaaaatttt agtatagagg
    29941 ttagttcaca atgttatcag ttacaagata ttcaatcaaa aatgttcgtt taaagccgtg
    30001 ggtaaagttt atttggtatt ttgagacaaa atcaaatata ctgttaaata ataagttact
    30061 tccgacagac agtatagata ttattctcaa tctttctgat gttatggaat ataaaattga
    30121 aaatcaagac tatactgcta gtaatatgca ttttaatgga ataagggata aacatggatt
    30181 tattattcaa catggaaata tacgtgttat agggatttct ttttatccat ttggtctcta
    30241 tccattttta aagataccaa tttcagagtt taacagacaa attgttgacc tagaagcagt
    30301 atcacagcta tttgcaaaaa aattggaaga gtcattaaat ccaacacaat cagtagaaaa
    30361 aattgtttta tatttagaag aagtattatt atccatatta gaagaagatt taatttcaaa
    30421 taaatatgta aagcttctaa attcatttat atatgttaat agatatagca atataaaagc
    30481 attttgtgat gatacaaata taaatattaa aacattggaa agaatctgtt taaaatatac
    30541 agggtataca cctaagattt taaagagaat ttacagattt aaaatggcaa gcaatcaact
    30601 tatttataat tataaagatg atgaactttt tgattttatt tatgaaaatg agtactatga
    30661 ccaagcacac tttataaaag aatttaaaaa attttcaggg acgtcaccaa ttaaatttat
    30721 tggtgagaat aagacgatta aagaaaatat aaagtacagc tatttataat tatactgtcg
    30781 attttttaca atacctccaa tttatttttt gatatgatat aggaaaataa attggaggtt
    30841 ttacatatga aaattattac agaaatagtt gagtttaatg tggaagaaaa tttatcaaaa
    30901 gaagagttta tagaaattgt aaatgactta gaattaaaat ttcattctat tcaatctggt
    30961 tttattgata ctgagctttt atatgatgaa aagtctcaaa agtggattat gatacaacat
    31021 tgggaatcta tagaagacct caagagtgct tctagtaaaa tgtttaaaga ttcttcaact
    31081 gagaaattta gaaaagcttt aaagaatcaa actgttaaga tgaatataat accacaaatt
    31141 aaaagttgga aattatagaa cttaatgtaa aagatagtta aatagtatca aactaaatta
    31201 gccaaataac attttgtatt taaattgtta tttggctttt agtgtttatt ttaatatgag
    31261 tgttatatac tagaaaaacc aaccttaaat actactatct aaaagcacta ttgctgtacg
    31321 agaggcaata ggcattttag aagaaggagg agttgagcta aagtatacat cataatctct
    31381 taagttttct ttttttgtgt ttcctccaaa ctctaccata tcagtattta atatcgtttt
    31441 gtagtttgta ttttgaaact ttgaaatatc aactgattgt attagattag ggtggaaatt
    31501 aaatataaat aaatatttgc ccttactgta caccaaaatc tttttatcat tatccatatg
    31561 tataagttca tgactatttt ggataaaaat atcactgtat tttgtaagtt cgagcataga
    31621 tttatcaaaa tttaataatt gtttatactt taagttgtta tcttctgaaa ggctccattg
    31681 tcttctggca tacttatagc tccaattgtt gccttctcgt ggaaaatcaa tccactcagg
    31741 atgtccaaat tcatttccca taaaatttag atatccttca cctgctagag aaaaagttat
    31801 taatttaatt aatttaataa gagatattgc tctattgata acatggttat ttgagtttat
    31861 ttccatattc cagtacattt ccttgtcagc tagccaaaaa ataattgttt tatcgccaac
    31921 taatgcttgg tcatgggatt cacaatatcc tatatttttt tctccaggtc gtctagtagt
    31981 aagttcatac cacatttttc ccaaatccca gtcttcatca gataagttag agatagtttt
    32041 tatccaaaaa tcaggtactc ccattgcgag tctatagtca aatccaattc cgccgtcttt
    32101 tatagggata cacataccag gcattccact catatcttct gcaatactta tcgaattagg
    32161 tttaatttct tttattaatt catttgcaaa ttggagatat gttatagctt caatatctgt
    32221 attcatacta aaatattttt cataactatc aaatgaaact ccaagaccat ggttatgata
    32281 taacattgaa gtcacaccat caaacctaaa gccatcaaaa tggtactcat ttaaccaaaa
    32341 ttttatattt gaaagcaaaa aatgtattac ttcaggttta ccatagttaa aaagttttgt
    32401 accccaagca ggatgatttc cctttgaacc tgagtggaaa aattgatgtt cacttccatc
    32461 aaactcattt attccttcta aagtattctt tacagcatga gaatgaacta aatccaataa
    32521 aacagcaatc cccattgaat gagcagtgtt tatgaggttt tttaagtctt caggagtacc
    32581 aaacctagat gagattgcat aaaagtttga aacttggtat ccaaaagatg cataatatgg
    32641 atgttccata atagccataa gctgaatggt attgtatcca gcttttttta tcttaggaag
    32701 tattttttca gtaaattcat tataagttcc aatagattcg ctttcagtag acatacctat
    32761 atgacattca tagattagtg gataagttat gttttttaag tcaaaatcat tgtcagtcca
    32821 gataaatgga gtttttggtt gccatatttg tccattaaat ccaccaaaat ctttttgaat
    32881 tactcttttt atatataatg gtatacggtc aaatgttttt ccatttgcag taacttgtac
    32941 ctttacctct gatttgtgag gtaagctatt ttgaccagga ataaatattt cccaattacc
    33001 agacccaatt tttcttagag gatgagattt tctattccaa ttattaaagt caccaattag
    33061 tgacaaacta tctgcatttg gagcccattc cctatagaag aatccatcat ttgtctgatg
    33121 aaatccatag taaagatgag catttgcaaa agaactaaaa tctttatagt ttttcaatgt
    33181 ttttgatttc atattctcat aatgtttcat tcgctttttt atatcagatt caaatggttg
    33241 taggtataca tcaatatcta aaattttaaa tcttttttga cttttcattg tatttctcct
    33301 ccataataaa tattacatct aaaaaataat atttatctca tactatcttc tctatataat
    33361 tgatatatat tatataatcc taataaaaag cttaagccac caatgattaa tttcataatt
    33421 tacctcccta gtatttatac ttatatatcg tattcatcaa aatttaaaag tttgtttaaa
    33481 actcttttaa taatatcata atcaaagcct ttataggaaa gatgttgaga aattttttga
    33541 tatattttct ttttatcttc tttctttact ctttcatacc ttttttttgc tagatacata
    33601 gcattttcaa attcagtgtc cttgtctaat tcagatactg cttcattgat tgtacttcta
    33661 ttgatacctt tattatataa attctgctta attctgtttt tgccacattt atttaggtta
    33721 acatttgtgt taacaatttt ttgagctaat acactgtcat ttacgagatt ataactttta
    33781 agaaaatcta tgaccctctc aattatattt tcatcaaatt ctgatgatag tttttctttt
    33841 aatttttttt cagattggtc agcatgagat aaaatattta atgctttatt tttagctttt
    33901 atatacattt catcatctaa aataggtttt aattcttctt catttatttc attccccttt
    33961 tttaaattaa atgtataaac aagttcttta aatatagcaa taaaaaattt atcatctaca
    34021 taaatattaa ctctatcatc atttcttttt tgttgttcta tttttgtaat tatacccata
    34081 agtcctcctt ttttatatgt aattatatta acaaaagcaa ctaataaaat ttaacaaaaa
    34141 acttatattt gtatgttata ttttatcaaa attaagacaa aatagtaaaa agttattttt
    34201 attaaaaagt aaagtagaat catgttaaat aattattttt ttaagtgttt tttagcatat
    34261 aaatataatt atatacccaa aaaaacaaat tataagcttt aagaaataaa aaataatggt
    34321 acaatagtat tataacatta aaaggagaca aaatatgaga agtgaaaatc tagttaagat
    34381 ggcagagttg aaaaatactg aaaaactaga gaaatttaat cgccataaag gcaaaatcaa
    34441 aataggtata ttgggaggta cttttgaccc tatacactat gctcatttag caacagcaga
    34501 atttattaga gacaagtatg acattgacaa aataatcttt ataccatcag gaaatccacc
    34561 acataaatta tgtatcacta cagataagta tgatagatat aatatgacac ttctagcaac
    34621 tgaaagcaac gaagattttt tagtttcaaa agtagaaatc gaaagaaaga aaaggactta
    34681 tacaatagat acattaaaat acttaaagaa aaaatacaaa aatgcagaca tttattttat
    34741 aacaggtgca gatgcaattt gtagtgttga agagtggaaa gatgtaaaga aaaactttga
    34801 gttagctact tttatagccg caactagacc aggaattagt ttgttaaggt cacaagagac
    34861 tatagaaaaa ctaactaaga agtataatgc tgacattata acagtttatg ttccatcact
    34921 ggatatatcg tccacatata taagggaaca gctaaatgaa ggcaagtcaa tacgttactt
    34981 agtacccgaa aatgtagaaa attatttata tgaaaataaa ctatatcaat atggagatga
    35041 ttaaatgaac ttagaaaata ttaaccaaag actaaatcaa atgctaccag tggggaggct
    35101 tagccattca aaaaatgttg caaaatgtgc tgaaaaatta tgtgagattt atggatgtga
    35161 caaagaaaaa gcttacttag caggaatgat tcatgattgt gcaaagtatt taagtgacaa
    35221 ggaaatagag gattatgtaa ataagtatga aatatattta gacccaatag aggatggaaa
    35281 tcgttccttg tctcatagcg taattggggc gtacatatgc gagtatgaat ttgaagtaga
    35341 agatgaagat attataaatg caatcaaata tcatacaaca gggagagagg acatgtctct
    35401 tttagaaaaa ataatttaca tagctgattt aattgaagaa ggaagaaaat tcccagttgt
    35461 agatacatta agagaattag catatggagg gaagcttgat gaagcacttt taacttcttt
    35521 taataatact ttaatgtttg tcatcaataa aaaagaagag atacatccaa gaacagttat
    35581 ggcaagaaac tatctaatta aagaaaagtt attataaaaa agctatataa aggcaaacat
    35641 attaataaat ttaaatttga ctatgttaca aaatcgtatt aatatgttac aataactaag
    35701 tgtattttaa ttaggaaagt gaggaatttt tatatgacag tggaacaaat gacaaaaata
    35761 gcatatgatg ccatagaaga taaactaggt caagatacag ttataataaa tataggaaaa
    35821 gtttctagtt tgtgtgatta ttttattatt actacagcat cttctcagag acaggtaaaa
    35881 gctattgctg acaatgtgga agatgaatta gcaaaactag gattagagcc aagaggtaaa
    35941 gaaggacaag gaactcaaac ttgggtactc cttgattatg gagacataat ggttcatgta
    36001 tttaatgagg aaaatagagg gttttataat ttagaaaaat tatggaaaga tgcaccttat
    36061 atagatattg acacattagc ataaacatga taatatatgt tattataatt agaaaatttc
    36121 aaaaattata ttaaattgaa tagactagag cagtaaaaga ttatattttt tcagagagtt
    36181 agtggaaggt gagaactaat attatataac tttgaactta ctagattaaa atctattctc
    36241 catggctgga ttaaaagcta tctaagagag tctatatatg tagtaggcta attagggtgg
    36301 taccgcgaag atttatcctc gtccctaaac gtaagtttag tgacgaggat tttttatttt
    36361 caaagaatta tttggaaatt ataagtaaat aatactaaat aaggtagtta tacacaatta
    36421 aaaataggag gcaaaatatg agcgtatata attttaaaga agtagaatcg aaatggcaaa
    36481 aaatctggaa agataataat cagtataaaa tggatactgc acaaactgaa aaacctaatt
    36541 attacacatt agaaatgttc ccttatccat ctggaaaaat acacatggga catgttagaa
    36601 attattctat aggtgatgtt gtcgcaagat tcaaaaaaat ggaaggatat aatgtacttc
    36661 atccaatggg atgggattct tttggattac cagctgaaaa tgcagctata aaacatggaa
    36721 tacatccgca taaatggaca atggaaaata tagaagaaat gaaagagcaa ttaaatttat
    36781 tagggattag ttatgattgg gataaagaag ttgcaacttc aactccagaa tactatagat
    36841 ttacacaaga aatatttttg aagtttttag agcatgggct tgcatataag aaaaaatcat
    36901 atgttaactg gtgtccttct tgtgagactg ttcttgcaaa tgagcaagtt gttcaaggag
    36961 catgtgagag atgtaaagca acagtattaa agaaagattt agaacaatgg tattttaaga
    37021 ctactgagtt tgcagaagaa ttacttaatg acttagatac attagatgga tggccagaaa
    37081 aagttaaaac aatgcaaaaa aattggatag gtaaaagtac aggagcagat ttagtttttg
    37141 atatagatgg aactgataaa tctatgacag tatttacaac tagaccagac acaacttatg
    37201 gagttactta tatggtactt gctccagagc atgaattagt taaagaattg gttgcaggga
    37261 ctgaatatga agcagatgtt gaagcttttg ttcaaaaaat gcatactatg acagaaatag
    37321 aaagaacagc agctgatgta gaaaaagaag gaatgtttat aggtagatat gttataaacc
    37381 ctttaaatgg caagaaagtt cctctatgga tagctaacta tgtattagtt gagtatggaa
    37441 cgggtgctat aatggcagtt ccagcacatg atgaaagaga tagagatttt gctgaaaaat
    37501 ataatttaga cataattgat gtaataacag aagataacaa aatgataaat tcagaagaat
    37561 ttaatggatt agatgcttca gaaggatttg aaggaataat cgataagtta gaaaaagaag
    37621 gtagaggaaa gagaacaatt aattatagac ttagagactg gttagtttca agacaaagat
    37681 actggggttg tcctatacct gtggtttatt gtgatgaatg tggaatagtt ccagttaaaa
    37741 aggaagattt accagttctt ttaccaacag atgttgaatt tactggaaaa ggggaatctc
    37801 cacttacgac ttcaaagcaa tttatgtcaa caacttgtcc tcactgtgga aaaccagcta
    37861 gaagggaagt tgatactatg gatacatttg ttgattcttc ttggtatttc ttaagatatg
    37921 tggatagcaa taatgaaaat gaaccattta gtaaggaatt agttaataga tggcatccag
    37981 tagaccaata tataggtgga gtagaacatg ctataatgca tttactttat gcaagatggt
    38041 ttgtaaaggc atttaagagt atgggaatgg tagacttcaa tgagccattt aaaaacttac
    38101 ttactcaagg aatggtactt atggatggtt ctaaaatgag taagtctaaa gggaatacag
    38161 tatctcctat ggatataata gatgagtatg gagcagatac tgcaagactt ttcgtattat
    38221 ttgcagcacc accagaaaga gatttggact ggtcagagca aggtgttgat ggatgcttta
    38281 gattcttaaa tagggtttat agattggttg acgagttagc agatgtggtt aaaaaggatg
    38341 tagagtttgg agaattaaat tcccaagata aggatatgag atatactata cactctacac
    38401 ttaaaaaagt tactgctgat ttaagtgaaa aattcggatt taatactgct atatcagctc
    38461 ttatggaatt aataaatgat atgtataaat ataaagagtt agataatata aacgaagcag
    38521 ttataaaaga aggtgtacaa actatagtaa ctataattgc accatttgcc cctcatttag
    38581 gtgaagaact atggactatg ataggtaaag aaggaagtgt atttgatata gactggccta
    38641 aatatgacga aaaagcttta gtaaaagatg aaatagaagt tgttgtacaa gttaatggaa
    38701 aagttagagg aaaattaact gttaactcaa atatatctaa agatgagatg gaaaaggtag
    38761 ctttagaaga tgaaaaaata aaaggattag ttgaaggtaa aactatagtt aaagttgtag
    38821 ctgtacctaa aaaattagta aatatagttg ttaaataact caaaaatatg aacaaaaata
    38881 taaatttata aaataaatga ggctgtctca aaatagagat aagccttttt tcattgttga
    38941 aattataaaa atagatttga ttttatacaa aaaaatgatt aaagaactaa aaagttcatt
    39001 cttatatacc ctagttgttg ttttaaatat tattataatt aatgttaaat cgagttaatg
    39061 tattaagtgg tatgtaaatc attcagtttc caaagtgttg ttcgtcaagg aactgctcta
    39121 agcttaaacg aaaaaaatat aattattgta ttttgaaatt tttttctata taatgaaaac
    39181 aggcaaaaaa ggtgcatatc tatgctttat atgaaacacc cagacaacga aattcagatt
    39241 catataatag ctaccatgtt tctaaaaagg aacttgtaaa aaagatagcg tttcaacttc
    39301 ccagttgatt aaaattatca gcaggaaaac aagtatggtc agcagtggta ttctaatggg
    39361 tgttgtcgat atatccaagt tgggattgtc tgaggatgtt atcaaataac ttgtgatagg
    39421 tgcagtagat gtggagattc ctgatacgga tttattctca ggggatggtt gcttcgggag
    39481 atatggagcg taaccagttt attgatatgg taaccatttt ttgtctaatt tgatgaaaga
    39541 atcccaagaa taccatacag aagtaagaca ggaattaact ggtggtataa actgataaag
    39601 gcaaatttaa aaattttgat aggatgattt taagatttat cttctatttt gttttttaga
    39661 aataattgaa atgttatgag gaggtatgta caaatggaga ctgtaacaaa taatcaatca
    39721 ggtgtagaaa ttcaactcag tctgtttgaa gctatcaaag atttattgtt aattaatcct
    39781 attttcttgt tgggaattat cttgattggt attttcttag ttgtaatatt caagaaaaat
    39841 agtgatattc caaaggtcaa aacatctatt ttatcactgg caatgtatta ctacttatgt
    39901 ttaacactat cgcatattgt tggtatacct acattcggtg aatatataag actgtcacag
    39961 ttaggggaaa cgttctttaa tccaaacata aatcttattc cttttagtga tggatttagt
    40021 ttgagtttta ttttgaatat tttacttttt gtcccattag gttttttatg tccgcttata
    40081 agcaaaacct ttgaacgttt gagaaataca ttcttgattg gttttggatt atctcttttt
    40141 atcgaaacta ttcagctttt tacgttacac agagcaaccg atatagacga cttactcacg
    40201 aacgtaattg gaacaataat aggctatttc tgcttcaaac tgattgctaa attgcgaatt
    40261 gtaaaactac attcagatga tgactctatg gaacaggatt acacagtatg tattccgatt
    40321 gccattataa tagttgccct tatattagga ttttttagtt aagttccaaa tagctaattt
    40381 gggaatccag acaatataac agatactatg ttacctttta caggagcata ctatctgtta
    40441 tattgtcaac atcctatttt atggtttgtg tgtagtttcc tgtaaactga actaaataat
    40501 taaatagaag ctattagaat taataataac agatagatat taataagcat aaacaaatag
    40561 taaaatgtgt agatatagac gtttttaagt gaaactatta taaaataatt gactgataat
    40621 caactgacaa aacctatttt tttaggttta actgacattt aactgacagt cagtttttac
    40681 tatttaaata gaagttcgct tagattgtcg gaagcttctt tgtccatttc tttaagtaca
    40741 tgagaatatc tattcatagt tatttttata tctgtatgac ccaatctttc agaaacaact
    40801 ttcatattag ttccccctaa aagcagcaga gtggcacttg tatatcttaa atcatgtatt
    40861 ctaatctttt ttaaattatt ttttttgtaa aattgtgaaa cgtttttctt agtgaagaag
    40921 gtagaaacgg atttaaattg gtgtttagac aaactaagtt atttctgttt tccaggatac
    40981 cttacaattt taatttgctt tgtcttagtt tttcaatttt caatttttca attaattctt
    41041 ttggagctga taaagctctt tttgattttg gtgtttttgg ctctttaaaa gatattttgc
    41101 cattagaata gacaagaatt tgattaacat ttatcagatt gttatctaag tcaacatctg
    41161 accacctaag cccaatagct tctcacattc ttaaacctag aagtaacatt aaaagaatag
    41221 gtatttctat attattacca agtaactttt ctattagcaa taatacttct tctctattgt
    41281 atatttcatt tgtagaatat ttttctttag aaggaagttt tataaaatca catgaatttt
    41341 cttgtatttc tcttaatcta tacgcttccc ttattacaga acttagaaag ctatacctta
    41401 ctttagcact agtaaaggta gaattattaa agttataatt tacaaaagct tgtactgaac
    41461 taggatttac ttctgtgagt tttagattct taaaaaaggt tctatgtaat ttttaaccca
    41521 agattttgta tttgtaacag tatatggaga ccaattattt ttattcatgt ctatatattt
    41581 ataacatctt tctacaaatg tcataccttt tggagcaaca aacttattat tatttatagt
    41641 agactttatt tcaattaaat gtttttcagc atcctttttc tttttatagc ttccataact
    41701 tttttgtttc tttttgccag tttcttattc cacatataca tagaattttt cccatctttt
    41761 tcttataaaa gctgatttga tattcatata tgtacgctcc ctttataagt tagttttata
    41821 aaagaacagt tggactgctc taattatgtc attatctttt taattcttta cagttacatt
    41881 ataacacgta tttgtataca cttaaattaa caggaagata aatatcgtta aaggaggaaa
    41941 agaaaattta atgtagaatt atgtaagata tatagtattt catatataaa agggggagat
    42001 attgtgaaat taaagaaatt attatcacta gggttagccg tgtcaatgtt tgctgctggt
    42061 cctatatcag ctaatgcact tgatacaatt tatactattc aaggaaaaga taaatatgaa
    42121 acggctgctc ttatagctga tgaacaaaat tatactacag ctatattaat taatgcagac
    42181 agcacaatgg ctgatggatt aagtgcgagt ggacttgcag gagcaacaaa tgcaccaatt
    42241 tttttaacta agaaaaataa catacctaat gcaactctta aaagagtaga gaaagctaaa
    42301 aaggtataca taataggtgg agaaagttct attgataaag caacagaaac tcttctaaaa
    42361 gataaaggaa tagaggctaa aagacttcaa ggtagtgata gaattaagac aagctataat
    42421 gttgcaaaag aaataaactc aattaacaaa gtaaataaag ttatattgac taatgctttt
    42481 aaaggagagc ctgatgcaat gagtgctgca cctgtagcag ttagagataa agcagctata
    42541 gtattaactg atggaaaaag tgttccattt aatacaactg gtgtagaaag ttatgtaata
    42601 ggtggtactt catcaatgag tgacaaacta gttaatgata ctaattcaac tagattaggt
    42661 ggagtagata gatatgatac taataaaaaa atagtaaata agttctataa tggcgcaaaa
    42721 gaattttata tagctagtgg tactgattta gtttatgctt tagttgcttc accaatggct
    42781 aaaaataatc ctattgtact agttgatatt ggaagtaata aagatatact taaaaatgct
    42841 gcaaaagtga ctgggatagg aaatctaagt gataaaatta tgctagagtg tgaaaatacc
    42901 atcaataata ttagtcttcc gtcttcaaat aaaaatataa tatgtggatt aaagattgat
    42961 tttgattcaa agcacataat ttggcaagat aaaggaagtt atcttgaatg ttatgatgat
    43021 aaccttgaat attatactga aaaatataaa gacccaacag ttcctataaa tatagaaaat
    43081 acaagtacac aaaatttaga tgtaacaaaa ttaaaagttt atggagaagc taattcaaca
    43141 ttatatatgg ggcaatatgc taaaataaaa atggatttta atagtttcgg tgtattaaag
    43201 ccaggagaaa aatgtactat ttatttagat ataatttcat tagatccatc aagaagcatg
    43261 acattaacat tttcttatgt aggtgataaa gaaaattata aatatgaaca aggattggca
    43321 agtagaatat tattttataa cccagatgga gaagattttt ttgaatataa ataactagtg
    43381 ggtatgtaaa ttaataaggg ttttataagt ttaatttttt tattttcgtt ttatattaac
    43441 tatgtggtat gtaaatgtct cgatattgct catatgttga gttattatat ttagtttcat
    43501 atgaactata tggattttaa aattaaaaat acttaaaaac atttacttta atagtaggtg
    43561 tttttttgat taaaagaata ttattataat gtaaaaagta ataaataggt aaaatatgta
    43621 agaattatat gttataatat ttttagcaag aagatgtaat ctacaattta tagagtggag
    43681 ttcatgtatc aaaaaattat cctcccgacg ctaagaaggg aggtgaatat acatggataa
    43741 ttttttacaa ggcatactag caagtctatc tgctagctta atagtttata tagctagcaa
    43801 actatttaga aagcgtaaaa aaccactcaa agcggcaact aagagtggtt gggaatttga
    43861 tttaaaaatc agattccata aaactaagta atttctaaat tatgaactcc actctacagc
    43921 aaaatagatt gtagttcttc ttgcttttat tatatcacaa attggtacag atattcaaaa
    43981 ataatatttt tatgatataa taaagtcata gaaattttgc agtgttcgat tttttgaaga
    44041 aattaaggct taacagttga aatataaggc attgaggact tgtgataagt gttatcaatt
    44101 gcactactca tggttcactg caaatttgag agatttgtat atgtgtaggc attggaaata
    44161 ctcaatttat tttggggttt tatattaact atatggaatg taaatatttt ttttatatat
    44221 aaacttctaa acttttacaa aagttttata ttaactatat ggaatgtaaa tacacttcca
    44281 acaagcattg tagggttgaa gtctacaggt tttatattaa ctatatggaa tgtaaattaa
    44341 atcgtattta taattatatc tacacttagt aaatgtttta tattaactat atggaatgta
    44401 aatccaatag accctccaat aactccagat attccttctg gttttatatt aactatatgg
    44461 aatgtaaata atgaactatc taaaccaagg tcataattta attgagtttt atattaacta
    44521 tatggaatgt aaattgtatc caaaaaatta caataatcat acgaattgct aatataagca
    44581 gtcaatatat gtgtacattt atccatttta tctctaaaca tataaattat tatcccccta
    44641 aaaaactttc ataaaaacaa aaagaacaat atctctttgg caactggcta acataactca
    44701 taagatattt atataagtct tagtccctat agctttgcgt cactagattt ctctagtttt
    44761 gccgatttag ttttattcta taactaaata atacaataga attagttatt attcaacaag
    44821 attgtttgaa aattgaataa atttataggt atgaacgtaa tttcacactt aaaaacagac
    44881 taaatacgta gaatatatag aaaaatttac ctgtagtttt tgtgataaaa agctcctatt
    44941 attaatttaa gctagataag tttgaggaag tgacataaat tgaaagaagg aatatattat
    45001 gttgaataaa aaattaccag atgcagaatt aaaaattatg aaatacatat ggaatactgg
    45061 ttataaaact gtaatatcaa aagatgttgc agattaaata gaaaaaacat atgcttggaa
    45121 gcatacaact acaattacac ttttagctag attaactaaa aaaggttttt tcatatcgca
    45181 gagaattggg aaacatgtac actatagagt attaataaaa gagaaagaat atctcaaaat
    45241 agagggaaaa agaatttttg gaggtctaca taacaatcca ttatcagaac taatttcaaa
    45301 attacatgat ggagaagaaa taactgaaga aaaaataata gaaataggaa attggataaa
    45361 aagctggaaa gatgaagatt aataaataaa aggtagctac taatataagt gctacctttt
    45421 ttcttgtgga taatattggg gataagttgt ggaaaatttg tgtaaaaatt gtggataaaa
    45481 tattttgctg acatttaact gacataagta ttagattttg atttaaaaat gttgaaatat
    45541 caataaataa ttaaatagaa gttattagaa ttaacaatag attccttttt caaagaagtc
    45601 tttgatttca tcaaggttat cagtttttcc aagtgctaag ataagtttta ttctagcttt
    45661 ttgacctggt aagtccccac caaatataca accaagattt tttaaatctc taccagaacc
    45721 aaagtaacca taactatcga atactctacc tgaatgacat ctagaaacta taactacagg
    45781 aagtcctttt tctctagcat attcaactcc agaaagcatt tgaggaggaa tattacctct
    45841 gcccattgcc tcaataacta tacctttata accactatca acagcaaatc ttataaagtc
    45901 agcattttct cctacatatg ctttaaataa ggcaacttta gattctacct tatcagtatc
    45961 tataattgtt ctatttacaa tatctcttgt aaggacaagt tcgttgcagt caattattcc
    46021 taatgggcca ctagttagag atttaaatgt atttagagaa agagtatttg ttttagtagc
    46081 ttcagaagct aataatactt cattgtttaa aactacaagg actccttttc ccatagcatc
    46141 tttggatact gcagtacaaa ctgatgcaga taaattactt gaaccatcat atccaagttc
    46201 agaactactt ctcatagcac ctgtgactat tacaggtttg atgttgtcaa ttgtaaggtc
    46261 tagaaaataa gctgtttcct ctaaactatc tgtaccatgt gttattacaa cacctgtaat
    46321 atcttttctt gctaataaat catttacata atttttcaat tccatcattc tataaggtgt
    46381 tatgtgaggt cctggaattt catcaaaatt aaaaacttca acatctgcaa ctttatcaat
    46441 gttggtaacc attgatagta tttgttcacc tgataaagtt ggtatagctg ctccgacttt
    46501 atcatctact gtcatagata tagttccacc agtaaaaact atggcaactt ttttcttaat
    46561 actcatacta ttctctgcct ttcataaata aaatttataa ttccgatagg attatatcaa
    46621 aaaaagtagt taaggtctac ataaactctt ttattcatat aatttagata tttcagtgta
    46681 atataattat ttcttaattt tttgccattc aacgatataa ccatttaata tctctcttat
    46741 ggcttttcct atcttagtat aagcttcatc atatagattt gctagagata ttctaattga
    46801 ccattcaggg ccatagaatc catttccact aagtaaaact actgaatagt cattagctaa
    46861 tttataaaga acatctactg gagatgcagt tttacttata aatttaaata agtcttctcc
    46921 gtagtttaat ttagcccatt cttcaatatc aaattgagtg taatatgcag cattgttttt
    46981 gttttcatta attggaagct ctaaagcttc aaataatagt ttttgacgtc tatggcagat
    47041 actcatatta agttttttgt aggcatctac tttgtcaatc aatgcaaaag cagagaaaaa
    47101 cgccatttgt acttgctgtg gagtagaaag accagcagta tggttgagag caacaagtct
    47161 gctatcagca acaactcttt ccataaagga aagactagaa gggttaagac tcatatcact
    47221 gtaacgctta tctactgatt tttttaattc tccagttaaa tcatttattt tcttatcaaa
    47281 aacatttttc ttatgaaggg caaatgtacc aagtctccat cctgtaactc caaaatattt
    47341 tgaataagaa tatactccaa cagtgttgta aggtagtttt gacattaagg atgaaaaatc
    47401 ttctacaaaa gttccatata catcatctga tattatcatt aaatctttat tataattttc
    47461 aattacatct attagattat tacaagatgt ttcatccata gctatagaag caggattatt
    47521 aggattaaca acgaataaag ctttaataga tttgtcacga agtttctcta attctttttt
    47581 tgtatattgc catgtatgag cacctttttc atcaacttca ttagcattta tatttaccac
    47641 tttaaagtcg taacgaggaa ggttaggtat ttcaagataa ggtgtaaata ttggagtcat
    47701 taaggctatg gtatctcctt tttttagaag ttcatttgcc attaatgaat caaatatata
    47761 gcacatagca gctgtagcac cttcaacagc aaaaatttct acatcaccat atttacctga
    47821 tatatcatat ttcatttctt gaactaggta atcgtgtact attttttcca tatgaggtaa
    47881 cattctatct ggaagtggat agttatcacc aataattcca tcagctagtt catgaacaaa
    47941 ttcatctcca tcaaatccaa gttcatttat accaaagttt ataatatctc tagctaaata
    48001 tgctccaggc atatctatat tttcatttat aaatttaaaa aatctttctt taataccctt
    48061 tttttgaggc attccagcca aatgacctaa atcccaatta gaacgagttt cagtaatagc
    48121 gaaatgacca aaagtaaaaa aggcttctct agcagttgaa caagtccagt ttggatttcc
    48181 acgacctgca tcaagtaatt ctctgttatt ttcttttgca gtgtattttg caatatctat
    48241 taatttgtcc ttaaattcaa aagggcttat ttttccatat atgtttttga tttctttata
    48301 agtatgattt ttcatgttaa attcctcctt atgtaataag tttcacattt ttataataaa
    48361 ataaacaagt tgcaaaaatg attatacttt aattataata ggtttataga aaaagtaaag
    48421 tatgaaatta aaataataac tctatttagc cttattaaat atatgttaaa ataaaaaata
    48481 ccttttaata aaaaatgatt gttatataaa ataaatattc aatttaatta tcaccttagt
    48541 ttttttattg tattttatta tatatgtata gttttctaat tttgaataaa aataaagtaa
    48601 aactttcttt tatattgaag ttgtttagta agatatgtat t
//
LOCUS       DAGQVA010000021        46844 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.021, whole genome shotgun sequence.
ACCESSION   DAGQVA010000021 DAGQVA010000000
VERSION     DAGQVA010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46844
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.021"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            195..1202
                     /locus_tag="MIV85_001394"
     CDS             195..1202
                     /locus_tag="MIV85_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBY2960740.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIYFFIFIIESLKLISINQFQLMYLMLILISSLCVIVYSYKITSLYIFKNF
                     KIGILLFFYFLFSQIIFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSF
                     LQSILFDRFGKKIGIVMVGTCWSLWHLPLQFTLYSPQTPIIGAIAHLIYGIGLSIFLG
                     YVYMKTKNIWFCSIMHVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEY
                     K"
     gene            1582..3108
                     /locus_tag="MIV85_001395"
     CDS             1582..3108
                     /locus_tag="MIV85_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBY2960741.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            3136..3693
                     /locus_tag="MIV85_001396"
     CDS             3136..3693
                     /locus_tag="MIV85_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960742.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            4215..5258
                     /locus_tag="MIV85_001397"
     CDS             4215..5258
                     /locus_tag="MIV85_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960743.1"
                     /translation="MLKKWFGIVKKRQKSESAKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            5369..6511
                     /locus_tag="MIV85_001398"
     CDS             5369..6511
                     /locus_tag="MIV85_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBY2960744.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            6965..8356
                     /locus_tag="MIV85_001399"
     CDS             6965..8356
                     /locus_tag="MIV85_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBY2960745.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            8609..10402
                     /locus_tag="MIV85_001400"
     CDS             8609..10402
                     /locus_tag="MIV85_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBY2960746.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(10483..11865)
                     /locus_tag="MIV85_001401"
     CDS             complement(10483..11865)
                     /locus_tag="MIV85_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBY2960747.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            12123..12470
                     /locus_tag="MIV85_001402"
     CDS             12123..12470
                     /locus_tag="MIV85_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBY2960748.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            12488..13522
                     /locus_tag="MIV85_001403"
     CDS             12488..13522
                     /locus_tag="MIV85_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960749.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(13571..14620)
                     /locus_tag="MIV85_001404"
     CDS             complement(13571..14620)
                     /locus_tag="MIV85_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2960750.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            14895..16430
                     /locus_tag="MIV85_001405"
     CDS             14895..16430
                     /locus_tag="MIV85_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960751.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(16615..17301)
                     /locus_tag="MIV85_001406"
     CDS             complement(16615..17301)
                     /locus_tag="MIV85_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBY2960752.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            17426..18808
                     /locus_tag="MIV85_001407"
     CDS             17426..18808
                     /locus_tag="MIV85_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBY2960753.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            19210..20478
                     /gene="eam"
                     /locus_tag="MIV85_001408"
     CDS             19210..20478
                     /gene="eam"
                     /locus_tag="MIV85_001408"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBY2960754.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(20571..20927)
                     /locus_tag="MIV85_001409"
     CDS             complement(20571..20927)
                     /locus_tag="MIV85_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960755.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(21078..22172)
                     /locus_tag="MIV85_001410"
     CDS             complement(21078..22172)
                     /locus_tag="MIV85_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBY2960756.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            22636..23457
                     /locus_tag="MIV85_001411"
     CDS             22636..23457
                     /locus_tag="MIV85_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBY2960757.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            23478..24674
                     /locus_tag="MIV85_001412"
     CDS             23478..24674
                     /locus_tag="MIV85_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBY2960758.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            24841..28239
                     /locus_tag="MIV85_001413"
     CDS             24841..28239
                     /locus_tag="MIV85_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBY2960759.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            28249..29922
                     /locus_tag="MIV85_001414"
     CDS             28249..29922
                     /locus_tag="MIV85_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBY2960760.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            30195..30389
                     /locus_tag="MIV85_001415"
     CDS             30195..30389
                     /locus_tag="MIV85_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBY2960761.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    30558..30791
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            30868..32265
                     /gene="asnS"
                     /locus_tag="MIV85_001416"
     CDS             30868..32265
                     /gene="asnS"
                     /locus_tag="MIV85_001416"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBY2960762.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(32438..33613)
                     /locus_tag="MIV85_001417"
     CDS             complement(32438..33613)
                     /locus_tag="MIV85_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2960763.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            34032..35396
                     /locus_tag="MIV85_001418"
     CDS             34032..35396
                     /locus_tag="MIV85_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBY2960764.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            35418..35909
                     /locus_tag="MIV85_001419"
     CDS             35418..35909
                     /locus_tag="MIV85_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBY2960765.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            36181..36852
                     /locus_tag="MIV85_001420"
     CDS             36181..36852
                     /locus_tag="MIV85_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBY2960766.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMKRLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            36937..37803
                     /locus_tag="MIV85_001421"
     CDS             36937..37803
                     /locus_tag="MIV85_001421"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBY2960767.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            37836..39338
                     /locus_tag="MIV85_001422"
     CDS             37836..39338
                     /locus_tag="MIV85_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBY2960768.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            39468..39920
                     /locus_tag="MIV85_001423"
     CDS             39468..39920
                     /locus_tag="MIV85_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBY2960769.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            40080..40883
                     /locus_tag="MIV85_001424"
     CDS             40080..40883
                     /locus_tag="MIV85_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960770.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            40941..41828
                     /locus_tag="MIV85_001425"
     CDS             40941..41828
                     /locus_tag="MIV85_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBY2960771.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKDMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            41847..42695
                     /locus_tag="MIV85_001426"
     CDS             41847..42695
                     /locus_tag="MIV85_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2960772.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            42758..43447
                     /locus_tag="MIV85_001427"
     CDS             42758..43447
                     /locus_tag="MIV85_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBY2960773.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(43777..44967)
                     /locus_tag="MIV85_001428"
     CDS             complement(43777..44967)
                     /locus_tag="MIV85_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBY2960774.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYAWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLDDGIDTAGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSERGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEPKVILTPEQEERLLAFMETDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLRDSEIGYYIDTPKTKNGKRKIPLTE
                     RAYQALQRILKNRVKAQPLVVGGYSNFLFLNREGLPKVAGNYVGMVRGLIKKYNKYHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(45045..45248)
                     /locus_tag="MIV85_001429"
     CDS             complement(45045..45248)
                     /locus_tag="MIV85_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBY2960775.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(45630..45878)
                     /locus_tag="MIV85_001430"
     CDS             complement(45630..45878)
                     /locus_tag="MIV85_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2960776.1"
                     /translation="MKHTFKKPSYYLLSQAMDGDEKAIEKVLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGLIREALIKMILGFDIALEIEEE"
     gene            complement(45882..46301)
                     /locus_tag="MIV85_001431"
     CDS             complement(45882..46301)
                     /locus_tag="MIV85_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005361151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2960777.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRHVVKDYQQGLKRRKEKEISFC
                     ELPEIMVENLAVWDDYETDYTIFNVCGNDIRVYDDELAEALKQLSERNRETLLMYYFL
                     EMNNEEIAKKQNISRSGVFQNRHNSLALMRKLLKEKR"
BASE COUNT        18046 a         5408 c         7999 g        15391 t
ORIGIN      
        1 taaactgatt gcataaaaat gatttttata taaattttaa acagaagaat aaatttctaa
       61 cgaaattgga tatttcttct gtaaatacat attcaaaaaa agaattataa gagtttagtc
      121 agcagtcgtg taagtaataa ggactttata aatatataga aatataatga tatgagtata
      181 agtagaaaaa ttttatgatt tttacaatta ttttttataa aaaagggagg ttatgtttgt
      241 tgaatttaca atcaaaatgg gtaaactttt taaagccaac atatgtcagt gatgaaataa
      301 aaagaaaaaa actacaagtt ataatatttt tttctataac ttatggttta tcttattcac
      361 taggtttatt agcaatatgt tttaatcatt taatagattc agaaatttta gctcaattta
      421 tgatgatatt gccattatct tcagtttcta ttgcaaaatt ttacacagag ggaagaaata
      481 atgataaata taatttctat tcatcagtaa tattattttt tattatttac ttttttatat
      541 ttattattga atcattaaag ttaataagta ttaatcaatt tcaattaatg tatcttatgt
      601 taattttaat aagtagttta tgtgttattg tttattctta taaaataaca agtttatata
      661 tttttaaaaa ttttaagata ggtattttgc tattttttta ctttttgttt tctcaaatta
      721 tttttggatt aataataagt gataatcaat ttgattataa gaatttcttg aattatattc
      781 ttcttcctat aatatcatta gtatacattt atcctttttt atgtgaagag tatggttgga
      841 gatctttttt gcaaagtatt ttatttgata gatttggcaa aaaaataggg attgtaatgg
      901 taggcacttg ttggagttta tggcacttac ctttacaatt tacactatat agtcctcaaa
      961 ctccaataat tggagctata gcccatttga tatatggtat tggactttct atatttttag
     1021 gttatgttta tatgaaaact aagaacatat ggttttgctc tataatgcat gttctaatta
     1081 atagcttagg attaattttt aatgattctg aaataattat taattaccat agtattatac
     1141 aaagattgat atttatacta ttattttata ctccttttct atttacaaaa gaatataagt
     1201 aagaattaca attaatttat ataaaataaa tttttaagta aatattttta tagagagatt
     1261 gttatattac atatcagaaa aatattaaac taactaaatc aataaaaaag ttggtggata
     1321 acaatttata attgttagca caacatcatc ttatgtattg aaatctaaaa tatcctcatt
     1381 tttacttagc ataaatacta ttaattaaga aaataatata gaaattataa atatatataa
     1441 gtttagtctg gtgtataaaa caagaaaact aagtgatttt taatttaact ttttattaag
     1501 cttatttttt atactattta taataaataa actccatgat gggaaaacta ttactattta
     1561 atatgtaaag gagtatttta aatgaatgaa tcatattggt ttttaaactc aagtccaaaa
     1621 gaatataaca aattaggtga aaatataaaa acagattgtc ttatagtagg tggtggaata
     1681 actggattga caactgcata tttattagca aaagaaggta aaaaagtagt gcttgttgag
     1741 gctgataaaa taggatatgg aacttctgga aggaatactg gtaaggtaac ttgtcagcat
     1801 gatatatttt actctaagat agagaaaaaa tatggattag ataaagcaaa atcatattat
     1861 aatgcaaata atgaagcttt aaatttagtt gaacaaataa tagaagaaaa caatataaaa
     1921 tgtgatttta aaagggaaac ttcttttgta tttacagaaa aagaggatac tataaaggat
     1981 attaaagatg aatatcgtac atgtaaaaaa ataggaataa attgtgagta tcatgaaact
     2041 atagaaaata ttccattaga tataaagggg gctattagtt ttactaatca aggtcaattt
     2101 aacccaaaga agtatattga tggattggca aaagcagcag taaatttagg gctaaaaata
     2161 tatgaaaata caccagtagt agaccttgaa aaaggaaaaa tatgtagggt taaaacaaga
     2221 gaggataata taatagaagc tgagaatgtt ataatttcat ctcatagtcc atggtatgat
     2281 ggattgaatt tttattttgc aaaagaatat gcagagcgtg cttatttaat ggttgcagtt
     2341 ttggaaaata aattagcaga tggtatgttt ataagtatag atgacccatc aataactttt
     2401 agacaatata atgatggaag tgaaaattta ctgatttttg gaggaggaga ccataaagtt
     2461 ggtcagggag gaactgagaa agaaatattt gatgatttag agcattatgg taaagaagtc
     2521 tttaaggtaa aagattttaa ggggaaatgg tctgctcaag acaatatgag ttttgacaat
     2581 gttccttata ttggttatat caacaaaaga gaagacaata tttatgtagc tacagggttc
     2641 tctaaatggg gaattactaa tggaactgct gctggaataa taataaaaga tttgataata
     2701 aataataatt ctgattataa agatactttt aatccatcca gattaggtag ctacttttca
     2761 aaagatttta taaaggaaaa tgcaaacgta gcaataaatt atgtaagtgg aaaattaaaa
     2821 ataggtagtg gagatatgcc taaaaataat ggagaaggaa agattgttaa tattgatgga
     2881 aaaagatatg gtgtatataa ggatgataat ggagattttt atattgtaga cactacatgt
     2941 actcatttag gatgtgaact taatttcaac agtgaagaaa aaacatggga ctgtccatgt
     3001 catggttcta gatttgacta taagggaaat atacttgaag gaccagctct taagccatta
     3061 aaactttatg gacatggtga taatgatgtt aatcctaagt tattataaaa ttatttttag
     3121 gaaggtaaag tgtatatgaa taaactttta aagccaataa ctatactatt gtatatagtt
     3181 tatattttat ctgccgtatt ttttgtagca aacaaagaat atggaagtct aggtctggta
     3241 gcaattagtt tagttggtac tttcattttg agttttataa ataagcaaac ggaaagatta
     3301 ttgagtaaag aattatatat aatgcttgct ttatttataa tgttttcatc attgttaggt
     3361 acttgtttta atttttatga tataaattat tatgatgatt ttttgcattt atggtcaggt
     3421 ataatatctt gtattgtggc tttttctata attaaatact tttatacaca aagagagata
     3481 agtaaaatga gtaaagtgtt tttagttata tttttattta tgtttagtat gggagtagcg
     3541 agtttatggg aaataggtga atttttaatg gatacttttg ttgggactac tacacaggcc
     3601 ggagggttag aagatactat gattgatatg gtagatgctt taataggcac aattataact
     3661 attcctttta tagtaaaaaa atctaatata tagttttaaa ttttttatat taattataat
     3721 ggatttaatt aatcatgttg agtttcaagg tctatatgat taattaaatc catttttgtt
     3781 atttataatt attattgaat atatttttac atataagata taaggtgata gatagaaatt
     3841 gttggattat gtaaataatt aatatataat accattatgg gcaataaata caaatcaaat
     3901 gataatatag tctatttatg taaatgttat attgtatact aagtataata gtaagttttt
     3961 tgatagtggt gtagaaagta aaaatctact agcctaaatt gatgtatgga ttagtttagg
     4021 aacagtaatt gcatatctta agtttgatgt catgttgggc tactagaaat aggtcatctt
     4081 tttcacttga atatcttttc tttaaacatg gagagtatca tatcaaaaac atatgaaaat
     4141 taagtgattt ataagaacag taatatttta tatgatagta tagaatagta ataaagtatt
     4201 aggaggaaca ttgagtgtta aaaaagtggt ttggtattgt gaaaaaaaga caaaaaagtg
     4261 agtcagcaaa agaagaaggt gaagtaatat taaaaaacga aaaaatatta tctgaagaaa
     4321 agttgataga tgaagaagga gttgtagtta atattgataa tgaaatatta actaaagtag
     4381 aagtagtaaa tgatgataat gaaatagaag aaaaaataat agaagaagat tggttaatta
     4441 gtgaaaatac cataaaatta gatgataaag aagcaattat taatgataaa aacatagaat
     4501 tatgtaaaaa agaagttcaa gttgaaagtg aaaaaatagg tttaaataag tttgaaggac
     4561 ttgaccaaaa tgaaaattat aatctagaaa aaaatgttat tgaagaaaaa aaagtaagtg
     4621 aatgtttgac agaagaagat ttagagtaca taaaagaaat taaaataaaa agaggaaaaa
     4681 gtataaaagc tataaacttg tatactaaag aagagtgggt ttttgacact catatacagt
     4741 gtagtaaaaa actcaaagtt ccattagggt acataagaga aaatttaaaa tatggatata
     4801 tggattactt tggagatgca ataaattatt taagtgaagt attaaatata gatgaatact
     4861 gcaaaagtga atggagctat ctcgataata gcaaatctcc atctgagata tttaatattc
     4921 taaacaataa aatatttagt ataaggcttt ctaatgaaaa aagaaatgaa attttgacaa
     4981 atgataaaat tgaagcatta aaaatgaatt atagatttga atgtattgat gaagaatatg
     5041 atgaatattt taaaaaatat aagtctataa tcaaaagagg tggaaagaaa aaagttgaat
     5101 tagtaaataa aaaaggtgac attttagaaa tatttaagtc tttagaagaa tgtgccattt
     5161 atttgcaaaa ggaaaagaat gaagttatac aaatgttaaa atatggagat acaaaagtag
     5221 gaagaaactt tataaggtat agtttgagaa gtatttaatt tcattttaaa ttcataagag
     5281 tttcatttct gattcacaca tttaatatta ttttaatgta aaataataaa ggtgaagtat
     5341 tgcacaatta aaattaagga gggtattaat gtctgaagaa aaaaatccaa aagaaaatac
     5401 attagatgaa tctaaaaatt cagataatgt aaattctaaa aaagatgatg tgtcagatga
     5461 aaaaaatact gataacaaag ttaaaaaaag ggaaataaag ctaaacaaca aaacacttaa
     5521 agctattgta gcaattgttg cagtaggagc tatatgttta ggtggaggct atgtttttgg
     5581 caaagaagct ggaagaaaat tgcctgctac ttcaaaacac tataatagca gtgaggtagt
     5641 agctactatt ggggataaaa aaataacagg tgaaatgtta agaaagagaa tggagccatt
     5701 attttattta aatgcaaaaa ctactatgac tgatgacgaa atacgttcat atgaatcaaa
     5761 tatgattgaa actatgatta catctgatat attatcctct gaagcagcaa aagagaaaat
     5821 aagtataact aatgaccaac tagatgctca gtataataat ttaatgagta gtatagaatc
     5881 agcaatggga atgactaaag aagagttttt aaaacagttt gatttgactg aaaaatatat
     5941 aaaagatgat atgaaaaaag agctagtagc atcaaaatat ttaaatgaaa aatcaaaagt
     6001 tactgataaa gaagcagaga actattacaa taaaaacaag agcaattatt tacaagttag
     6061 agcttcacat attttaataa aaactgttga tgataaaggt aagcaagtta gtagtagcaa
     6121 aaaagctgaa cttaagaaag aagctgaaga aatacttaaa aaagcccaag ctggggaaga
     6181 ttttgctact ctagctaaaa aatactctga agatagtagt gcagaatcag gtggagattt
     6241 aggtttcttt ggtaaaggtc agatggtgga atcttttgaa aaagcagcct ttgcattgaa
     6301 gaagggagag gtatctaaca aacttgtaga aagtgattat ggatatcata taattaagaa
     6361 aactgatgaa aaatatcagc catttgaaga ggtaaaatca gatttagtaa gcagtttaac
     6421 atcagaaaaa caaaacctac ttatacaaaa tctaaaagaa aaatataatg ttaaaattac
     6481 agataaatat caaatgaaag ctaaagaata gataaagtca atttattaaa aaaaagaaaa
     6541 attaactgta tggataaaag ctatttttac tcttaatata gagagtataa aatagctttt
     6601 attattttgc aataaaatct atttatatat atgaagtgac aaagaaataa catgcaaaaa
     6661 gatattaaaa agaaatattt ttaatttgaa ttttttcaat aaaaatttac aaaaatgaaa
     6721 aaacaaacaa aaaagaattg aagatttaag ttgttattta aatatatata tattaagatt
     6781 ttctgctgaa gatactaaaa aaataatatt tttcataatt ttaaaaataa taataaaaaa
     6841 atgaaaatac aggcgataat ctattgagta aacatagaaa agatgatatt ataagtatgt
     6901 gctaaaatgg ttaaagcaat attaatatta aatttaacta taaaacaaaa gggggcgttt
     6961 ttttatgtca agtacagaaa gcgtatctaa aaaaagtggt catccgaaga gtttttggct
     7021 tatttgcatg acaattttgt gggaaagatt tagttattat ggtttaacag ctttattggt
     7081 attatttttt acagcaagtg tagctcaagg tggtttaggt ctttctactc aagaagcaac
     7141 atccatgttt ggcttattta caggtcttat atatcttaca ccattagtcg gtggctggtt
     7201 agcagataaa gttttaggtc aacaaaaatg tatttctata ggtgcacttt taatagcaat
     7261 aggagatttc gtactatttg cttcatctac atctattgca atggtttggg taggtctatc
     7321 aataattatt ttaggaaatg gtttttttaa atcaagttgc tcaaatatag ttggggatat
     7381 atatcctaaa actgatgtgt caagaaaaga tgcagcatac agtttattct atatggcagt
     7441 aaatgtagga gcatttatag ctccaataat atgtggattg ctttctgata atgtatttgc
     7501 agtaagagga gcaagtggag atatagtatc ttatggatat aagatggcat ttttaatttg
     7561 tggtataggc atgatgttag gtatgattat atttacactt cttgcaccaa aattattaaa
     7621 tgaagtcgga aaatatcctg tgactaaagg taataaaggt gaaaaaattg agtatggacc
     7681 acttactaag ttggagaaaa ataggataat agcaatggtt attttatttt tatttgtggt
     7741 cttattctgg acagcatact atcaaacaca aagttctttt atgatttatg taagggataa
     7801 tgtaaataga actctatttg gatttgaaat gccagtagca tggcttacat cactaaatgc
     7861 tatattatgt gtggctttat gcccagtatt agctacccta tgggttaaat tatctcatac
     7921 caaaagaggt gatttctcta ttccagttaa aatgggatta ggaatgataa taatgggtgt
     7981 tgggtttata gttatggtat ttgctacatt agctaatggt ccagatggaa tggtaaaggc
     8041 tagtatattg tttatagtat tgacttatat atttacaaca gtaggtgaat tattcttatc
     8101 tcctatagga cttgcaatgt tcaataaatt agctccagct aagtatgcta cgttgtctat
     8161 gggagcctgg tatctaacaa gtttttttgc aagtttatta tcaggaaaga ttgctggttt
     8221 tacagccaca cttggttttt tacagatatt tggaggaata gcaacagttt taataatatt
     8281 tggtttaata ttattgggaa taagaaatgt attaacaaga ttaatggcta tggatttact
     8341 aacaaaagaa aaataattca tgacgaatta ttgtaaataa atgaattact ttaaataaag
     8401 gaagttacat ttaaatataa aattaaatgt aatttcctct ttgattatga aaaaaagctt
     8461 tacacaaata gatattataa ttaaaattat aattgtgata attagagtgt ataagattta
     8521 tataaattat acaaaaaata tttatgtaat aaactttaca tacttatata tttagttatt
     8581 caaactatta tttcgaggag gtcttgttgt gaatataaaa gatagattaa gtggattaag
     8641 aaaatttatg gaagaaaaaa atatagatgc ctatatgatt ccatcttctg ataatcacca
     8701 aagtgaatat gtaggagatt acttcaaatc aagagaattt atatcagggt ttaatggttc
     8761 agcagggacg gttattgtga ctaaagacga agctgggtta tggacagatg gaagatattt
     8821 tatacaggca gaatctcaat tagaaggaag tacaataaaa ttattcaaaa tgggacaaga
     8881 aggttgccca actacagatg aatatttata taaaaatatt cctgaaggag gaactttagg
     8941 atttgatggt agagttatat ctgctagaga aggagctaca ttagctgaaa aattatctaa
     9001 aaaaggtata aagatagaat atcagtatga tttaatagat agtatatggc cagatagacc
     9061 tgctttatca gatagtaaag catttttatt agatgttaaa tattgtggag aaagttttag
     9121 ctcaaaatta gctagattaa gagaaaaaat gagtgaaaaa ggtacttcta ctcatgtaat
     9181 aactactctt gatgatatag catggttatt caatataaga ggtggagatg ttaaatataa
     9241 tccagttgta ctttcttatg cagtaataac tttaaaagaa gtttatctat ttgttgatga
     9301 aagtaagtta aatgaagaaa tactaaatga actagctaag gaaaatgttc aaataaagcc
     9361 atataatgat gtgtatgaat ttgtaaaaaa tatagacaaa actgaaaaag ttttattaga
     9421 tggaactaag cttagttata caatttacaa taatatacct tgtgaagttg agaaagttga
     9481 tgagttcaat ccagtaatgt tttttaaagc tcaaaaaaat gaggtagaat tagaaaatat
     9541 aagaaattca catgtaaaag atggtgtagc tttcactaaa tttatgtact ggttaaagaa
     9601 aaatgtaggt aagatggaaa tcactgaaat aagtgctact caaaaattag aggacttaag
     9661 aagagagcaa gaaggtttct ttgagccaag tttcaataca attgctgcat ataaagagca
     9721 tgctgcaatg atgcactata gtgcaactcc agagtcaaat tataaattag aggcagaagg
     9781 attattttta gtagattcag gtggacaata ttatgatgga actactgata taactaggac
     9841 tacagtttta ggacctataa gtgatgaatt aaaactacac tttacttctg tagcaagagg
     9901 aatgataaat ctttctaagg ctaagttctt gcatggttgt agaggatata acttagacat
     9961 actatctaga agttgcatgt ggaatatggg aattgattat caatgtggaa ctggacatgg
    10021 tataggattt gtgctaaatg ttcacgaagc tccaaatgga tttagatgga gagtagtacc
    10081 tgaaagattt gatagtgcag ttcttgaaga aggaatggta actactaatg aaccaggtat
    10141 atatatagaa ggttctcatg gtataagaac agagaatgaa attgtagtta gaaaagctga
    10201 aaagaatttc tatggtcaat ttatggaatt tgaagttgtt acgttagctc ctattgactt
    10261 agatggtata gtaccagaat taatgaataa ggatgaaaaa gattatttaa actggtatca
    10321 taagttagtt tatgataaaa tatcaccttt cttaactgat gaagaaagag aatggttaaa
    10381 agtttacact agagctatat agtttgtact agatacaata aaaatcgagg tattataatg
    10441 cctcgatttt ttattgtata ttttattaac tttaaaaaat ttttaatttg ataattctac
    10501 taatttttta ttcattataa gtagtataat tccaaatatc aataaaaatg atggtatcac
    10561 tatgaagact tgtaacatac caagttggtc tataatagct tgcgtatagc cagataattt
    10621 atttgctgca aatttgccta aaaaccaaac acccattagg aatgaaatat acttttcagg
    10681 cgaaagttta tttaccatac catacccgac tggagaaaag caaatttctc ctatactttg
    10741 gaatgttaaa aatccaacta cccaaaatac acttgctttg tgaattgaat tagggtctgt
    10801 tcctgtttgt ataactgcta ctatcataaa caaaaatgct atggctaata gtataaaacc
    10861 taagctcatt ttttttggca cacttaaatc gcctttttta gtttgagata attttaccca
    10921 tactaaagca gagataggtc caagaataac acaaaggaga ccattgtatg aatctatcca
    10981 tgaagtagga atttgaaaat tgccaacagt aagatttatg tgttcctttg tatagagtgc
    11041 aatagacata gaggcttggt tatatgctat ccaaaaaaat actgtgaaaa aagctaacac
    11101 caatattact attattcttt ttttctcaat caaagttaaa ggtcttgaag ctagcatttt
    11161 cttatattct agtgattttc ttatagactc tctcccgtta ctagggtcat tattcaaagg
    11221 tttataaaac tttctgtttc caaatataaa gaagaataaa cctattagaa ccgtaattga
    11281 tgaaaataaa aatacatatc tatatccata catacttata gataatccgc ttttcatagc
    11341 aaaccattca ttagcaacta aaccgcatat taaagggcca aataaggtac ctagattagt
    11401 agccatatac gtaatagaga aagctccatc ttttcttggg tcatcattgg tatataagtt
    11461 tccaaccata gtatgtaagt ttcctttata aaaacctatt cctaatccag ataaaaatat
    11521 catgatgttt atatccatct tactatttgc tatgtatcct agaaaataac caattgaaac
    11581 cattagcatt ccaagtataa tacagttttt gggacctaaa aatctatcac tgacccatcc
    11641 accaataact ggagagaaat aagtccatgc taaaaaagat gcaagcattg atgcggattc
    11701 tgctggtgtt aaccctaaac cacctttgga gacttgttca gctaaaaaca ataataatac
    11761 caatttcata ccatagtatg caagtcctac aaaggtaaat attgaacagc agaaatataa
    11821 atctctaggt tgtttaagtt tttcttgcgt ttttaaaact gacatatgtc gagaacctcc
    11881 agataaatag tttaacaaaa ttttaccata ctatatgagt atatgttttt ttcatataga
    11941 cgtcaacttg taagataatt taattaagtc gaaatatatg taaaaatagt atcatttttg
    12001 tgtattcagt aatatttttt tatgataata tatgttatta ttatattaaa atacaaacat
    12061 atttatggaa aggatatgcc aatttagtag ttagattgat tgtttggcag gtgggatgag
    12121 ctatgataag aaagaaatct gaattacaag tagaagtaaa agaaaattta aatggtggta
    12181 taggaaaggt taagcttgaa aacataatac aaaatgaaga gcttaaagga aaaggaagac
    12241 tatttaaaag agtagcttta ccagtaggaa gttcaattgg tgtgcatgac catacaacag
    12301 attttgaagt atattatata ctaaagggaa aaggtaaagt atttgataat ggggaatttg
    12361 tagaagtaaa tgagggtgat gtagtgtata cagctgatgg cgaaaaacat tctatagaaa
    12421 atataggaga agaagatctt gagtttgtag cactagtttt atatatgtaa aatatggagg
    12481 aggagtcatg acaggcaaga tagaagaaat taaggacaag ataaatagat tttgcaactc
    12541 caatttaaat caagaataca aagatataag ctttaaaatt ttgcaaaacc ttttagataa
    12601 taataaagag ataattcatt cttctagagc tgatatatgg tcttcagcta tactaaatat
    12661 agttttagaa caaaatcttt tatacaataa gaagcatcca ctacatataa caaaaaaaga
    12721 gttttcaaaa caaataggtg tttctttaaa tactataaat aataaatcgt ctttaataaa
    12781 agatgtttgt agtattgact ttttaaatca agatactata gctatttcta atgtagaatt
    12841 ttgggtaaaa gagaccaatt ccaaatcaaa gtctgtagat ttagatttag aaaagaaaaa
    12901 aatactatat aaaagatata ttaagctatc acaagatgcg aatagtgata ttgaatcaat
    12961 tagatatatg gaggaagctg taaatatagg taaaagtatg attactaaag aagataaaga
    13021 acttggattt tggaaaggtt tatctaccag agcctatatg atagcacttg aatcccttgc
    13081 tagaaagtta gaaagtatta ataatctaaa ggagtccaaa aaagtattag aatatttaat
    13141 agaaattaat cctagtgatg agcagggaat aagatacaaa ttattaaatg tattaattag
    13201 attaaatgat agaacttcaa taaataaatt atttgaactt tataaagaag aaaaatctgc
    13261 tacatggatg tacagtaaag ctctttatta ctttaaaaat aaaagtatgt ttttggcaaa
    13321 tgattctatt aaggttgcta gaagtaaaaa taagtacgtt ggattatatt tgttagattg
    13381 gcgaaatgct tttggtagag aatttgttac agaggaagaa aaggcagaag ctgtctatta
    13441 ctatgatgaa aacatagtga tttggaatga agttaaaggt tctatggatt ggctattaaa
    13501 aaaaatgttg gaattttcat aaaaaaaact actccttact tttatataag taaaaggagt
    13561 agtttttaat ttatacatct agttttaaat cttcaggttt tattagacct ttttttctca
    13621 taaattctga aatcaacaaa gttacaatag caggaagtat aaaattaagt aaaagtatac
    13681 caacccacat agatatacct ccttttccag cactttgcat agcagttact gttccaaatt
    13741 gtccaaccaa tccacaagta cccataccag aaccaatagg aatattctcc attttgaata
    13801 ttgttgtaga taatggtcca agtaatattg aagctacagt aggtggtatc caaattttcc
    13861 aattttttat tatattaggt acttgcaaca tagatgtccc aagaccttgt gccacaaggc
    13921 cgccaactcc attttctcta aagctcataa cagcaaagcc taccatttgg caacaacaac
    13981 ctacagttgc tgcaccacca gcaagaccac ctaaacttaa catcatacaa atagctgcac
    14041 tacttatagg taatgtaaga gctattccaa caagtgcaga gactaaagct cccattatta
    14101 taggttgcat agttgtagct tgcattatta tatttccaaa tgaagtcata aaagcagaaa
    14161 cagctggacc aataagttca gctacaagta ctccaattag tattgttaca gcaggtgtaa
    14221 ccaatatatc tatttttgtt tcttttgaaa ctaattttcc aacctctaca gcaaaaagtg
    14281 tagcgacaaa tgctccaaca ggtcctccta attcattacc acaagctcca acaagtgcac
    14341 aagaaaatag tacaagtgga ggtgcttgaa gtccatacgc aatagccact gctatagctg
    14401 gaccagtaac ctgtttagca agagggctta taacttcagt aaaaagagaa atattgaaat
    14461 tatctcctaa tgtattgaaa attgttccaa ttaaaaggga cgaaaaaaga ccgagtgcca
    14521 tataacttag tgcgtcaata agataccttt gaacagaaat ttcaatattt tttcttttag
    14581 caaatgattt gaaatttctt tttttataat tgatttccaa tttaaaatcc tcctcatata
    14641 atataagtat aatttctttt taattaatta tataactttt cagctgacaa gacaaatgtt
    14701 atttcactaa aattagacta ttgtaatagt aagaaattaa cattaatttt agttttaaat
    14761 tttaaattta tggtttataa ttagtatagg gatattctga aatataataa ttttccagtt
    14821 tatcccaata tttaacttag gtagattgct tacaaaacaa atgattatat attaggctaa
    14881 aaggaagtgg atagatgata tttgtaaaaa ataagaaata cagaaaaatt gccataatta
    14941 tatctattcc tatattgctt gttgcgcagt actacctttt taaatttgga atacttagac
    15001 caatggtaaa gggagtagaa attgaaattg tagatgggga atatgttaaa gatatagata
    15061 aatatgtagt aaaattaaat gaaacagtta ctttgtctac aggtgaatat attaaggttc
    15121 cttcgtatgc taaaaatcca aatatttggt ttaatgtatt ggataactca gggactttaa
    15181 aaatagatgg aaataaaatg acagcattaa aggttgggta ttcttctgtg ggtatcatga
    15241 aaaattcaag agtattaaaa aaggctacta taaaagtagt agacccagag gtagaatcac
    15301 tagatatgga gattaatggg gatttaaaac atgttggtga tagtgctact atagaaagta
    15361 caatagaagt tgattatgat aagtttaaaa aatcatataa gccagtttat aagagtagca
    15421 atgaaaatat tttaaaaatc aaaggaaata aagtaagtgc agttggagtt ggtaaagcta
    15481 caatatatgc taagtgtgga aataaagaaa ttgagagaac atttaggatt caagctagag
    15541 ttgctgaaat aaatatggat gatataaaaa tagaagttga ccagaatgaa aaattgaaac
    15601 cagatataat aacttctcca cctggtttag aaccaccaaa aatatattat gagttagtag
    15661 attcaaaatt acctgtagaa agagcaataa gtttaagtag taatggaaat gttgtagggc
    15721 ttagagaagg taaagatagg gtgagaataa cttgtggaga taaatctaaa gtaataacag
    15781 taacagtagt caaagaaact ataacgaatg actatataca aaacttggtt ggttcacata
    15841 aaatagtaaa caataaagtt attattaaac ttgaatggga ttatatgaaa gatgtctttg
    15901 attatgatat atatcttaaa gataagttgt caggagaatc atttaagaaa attaaatcta
    15961 taactataaa tgaaagtgat ttaggtaagt ctaacaaggt atatgcaact atagaagtag
    16021 atatgaaggg taatcaaaat atagattttg atatttatgt cataggtaaa aaggattcag
    16081 atacaactaa gccaagtaat gtaataaata ttaccaatgg aaatggaaat tcaaataatg
    16141 ataataatat taaagatatg agggtagaaa atatatcagc taatgttgat agagataata
    16201 atgtcattag agttaactgg agtagtatat ctcataagga ctgtacttac agtatatatg
    16261 taaaaaataa tactaatgga gatggagaat ttactctata tcaaagtgat atacagggaa
    16321 atgagcatac tataagtatt cctgaaggag atttaaatct agatatttat gttgttgcaa
    16381 attataatgg aaatagctct caaaatagtg atgttataaa tgtaagatag atttgtatac
    16441 aaattgaaag tgttgagttt atttaaatat taaattaaga aaaaggatag tatagggtaa
    16501 ttatactatc cttttttgtt acaatatata ggtttaaaat ctctagtaat ataaattata
    16561 aaaagtctta tttacacaaa tctatagata ttttttttat taatcaatat tgtcttaaat
    16621 tgaacttagt gcggcttcta ttgcatgtat tactgtcgta tcaaatagtg gaatagaagt
    16681 gtcattttgt ttaattaaaa gacctatttc tgtacatcct aatataacag cctctgcacc
    16741 ttgtttgcca agcttatcta taatagataa gaaagctttt tttgaagatt cagatataat
    16801 tcctaagcaa agttcattaa atattgtgtc atttactatt atacggtctt cttcatttgg
    16861 aattaagact tcaattccat tattaataat tacattttta taaaaatctt gttccattgt
    16921 atatttagta cctaataagg ccactttttt tatttctttt tcccttaata ccgtagcagt
    16981 tacatctgct atgtgaagta atggaatatg tatactttct tgtattttat ctgatacctt
    17041 atgcatagta ttagtacaga taacaataaa atctgcccct gcctcttgta atttaattgc
    17101 agcatcagct aaaattttgg cgcttttttc ccaatttcca ctagattggc attcttcaat
    17161 ttcttgaaaa tctacactgt aaagtataca tttagaagag tgtagtccac ctaatctttc
    17221 ttttattact gtattaataa cttgataata tgtaatggta ctttcccaac tcataccacc
    17281 aattaagcct atagtcttca tattatacct ctcttattta tttattttga aatagctatt
    17341 tacaaataca agtatagcat ctaaaataga agcatacaat aataaaattg tatggagtac
    17401 aattataatt aagaggagta attatatgcc aataaattct tttgaaaact atcctatgac
    17461 atggaaacca aagttagata accgaaaacc accaatatat aaaactttag caatgttatt
    17521 agaagaagat attaaaagag gaaatttaaa tcctggagat aaattgcctc cacaacggga
    17581 attagcagat tttctagatt taaacttaag tacaataaca cgagcattta aactttgcga
    17641 agaaaaggga ctaatatgtg caaaagtggg aaagggaaca ttcatttctt ctgatgtaaa
    17701 tgtaagtaat acattattat atcaaacgga atcaaaagac ataattgagt tggggacagt
    17761 tcatcctccg tatgagcaaa atacatatat tattgacttt attaaaaatg tactaaaaca
    17821 accagaaatg gataggtttt tacaatacat gtctccatct ggcacatata tgcaaaaaaa
    17881 gtcaattgca aaatggatag aaagaaataa tgtatacacc agtgaagaaa atatattatt
    17941 atctacagga gggcaaaatg ctatatgtgc aactttacta ggattattta aagctggtga
    18001 tagaattgct acagattctt taagtttttc tggaattaag tcaatagcta aaatgatagg
    18061 tattcaatta gtcccaattc ctcaagaaaa taatgaaata tcgattgaat atcttgaaag
    18121 ttattgtaaa aatgaaaata taaaaggcat atatcttata ccagattatc ataatccaac
    18181 gacacatact atgtctgatt tatctcgtaa aaagatagcc aagatagcaa agcaatataa
    18241 tataataatt attgaagatg ctataaatag catttttaga gatggtatac aaactcccat
    18301 attttcttta gctagtgata atactatata tatttttagt acatctaaat ttttatgtgc
    18361 tggtcttaga gtagcatttg tagttgctcc aaaacgatat atagaaaatt tagaaaatgc
    18421 actatataat atgaatctaa tggtttctcc atttacagca gaaatagtac accgtttatt
    18481 atattctcct attatagata aaattataga agagaaaaga gatgcaatta tagaaagaaa
    18541 tgaagttgct gataaagttt tgtcagatta taatttgatt ggtgataaga attgcagttt
    18601 tcgttggtta cttcttcctg atgaattgga tggaaaatca tttgaaattt ctgcaaaaaa
    18661 tctaggagtt caagtatatt gtgccgaacg attttcagta ggaaactcta cagttccaaa
    18721 agcagttcgt atttgtgtaa cagctccaaa agatgtagaa gaattagaaa aagggcttaa
    18781 tataataaag tcacttctta agagttaaat ttattttact attatttaat taaataaata
    18841 aaaaggcgga gaaatttatt ataataaacc tccgctttta ttatttaatg aaatacttta
    18901 ctttttatta aaaaatttaa ttttaataat cttgaaaata taatcgtttt atggtaaaat
    18961 aattcttaaa aatagaaaaa attaatcatt tgttaaaaaa aatgcataat ttattgtaat
    19021 ttattgacga aggttgaaaa atattcataa atgtgcgaaa taacagaaaa aatgcaaaaa
    19081 ttaattcaat ttcatttgtt ataaaatcta tatggcaaaa ttaaatctgc ctatcagaat
    19141 gatataaaca catcagaaag gaggacgcta tcaaataata caagtagtta actttgatag
    19201 caaaaaatta tgaatgaaca aactagaata tccttagaga gagctgctga attaaaatca
    19261 aaaattgatg attatattca ggctagaaaa acgattaaca gaggtcttga aaaagaagaa
    19321 gagataaata aacgaaaaca gaaaatatta agtatcttaa atggaactga agaggattgg
    19381 aataactaca aatggcaatt atcaaataga ataacagatg tagatacttt atcaaaaatt
    19441 ataactctaa ctaaaaaaga aaaagaatat ataaaagagg ttggtactca atttagatgg
    19501 gcaatatctc catattattt gagtcttata gacccagaag atatatgtga cccaataaaa
    19561 ttactgtcta taccaacaca tatagagttg gaagatgagc aagaagattt ggacccaatg
    19621 ggagaagagt atacaaaccc agcaggatgt ataactagaa gatacccgga tagattaata
    19681 ataaatgtaa caaatgagtg tgctatgtat tgtagacact gtcagagaag aagaaatatt
    19741 ggacaacaag attctcataa gtcaaaagct attatccaag aatctataga ctatatcaga
    19801 gaaaatgaag aaataagaga tgtactagta actggtggag atgctcttac attaaaagat
    19861 gattatttag agtggattct tagccaactt aaagagatac cacatgttga ttatgttaga
    19921 ttaggtacta ggactcttgt tacaatgcca caaagaatta cagatgaatt ttgcaatatg
    19981 ctaaaaaaat atcaccctgt atatataaat actcatttta atcatccaat ggaaataact
    20041 aaggaatcta aagaagcttg tgaaaagtta gcaaatgcag gcgttccatt aggaaatcag
    20101 gcagtattat taaatggaat aaataatgat aaatttgtaa tgagatgttt aaatcaagaa
    20161 ttactgaaaa taagagtaaa accttattat atattccaaa gtaaacatgt aaagggaaca
    20221 aaacatttca atacatcagt agatgatggt cttgaaatca tggagtattt aagaggatat
    20281 acatcaggaa tggctatacc aacatatata gtaaatgctc caaaaggagg aggaaagact
    20341 cctttgcttc ctcaatacct tgtatcaaaa ggaacagatt acgttatgct tagaacatgg
    20401 gaaggaaaag ttataaaaat ggaagatgaa cctgctgtag atataaagaa acttataaaa
    20461 gaacaagcac aggattaaaa aaatatttaa agtttataaa aagaaacaac tttaaaataa
    20521 aaagaaaatg gatgtcaaat ttatatcaat ttgcatccat tttttattag ttatttatta
    20581 ttttgttgtt gattaactaa ttcaagatat ccacttgggt ggaagtaata tatctcagaa
    20641 gtattttcat ttacaaagta accaatatca ccatctgcat ctggtaaaaa tacataacca
    20701 ttaagatttt tagcttttaa tgcttcaaaa tcactagcat ttccttgata tatgtaatca
    20761 acttcattgt tgtattttac taaaagttct ttagcttgtt cttgagtcaa tttagtattt
    20821 tggcttacag gaacattctt ttgagaatct gcataagaag attcatttac tggtgcagtt
    20881 aataacaaac aagataaaac taataaagat ataagtgctt ttttcatact aaaaccctct
    20941 ttcatgttta attatataag attcattact taataatatt gtatgtttcc tataattaaa
    21001 tattaccatt aaagagaata atattacagt tacacagctg taacttttga ttacaaaatc
    21061 gtaattaaat tgtattttta ttccatttgt attttatcat gtctacgatt tacaaactca
    21121 cagaagtata tctttataac gcccatcaca ggagcagata gaatcatacc aggtatacca
    21181 aagaatcctc caccaacagt aactgctagg attgtaaaga atgggctaag acctagttgt
    21241 ccacctacga tttttggctc tataaatgta acttcaactt gttgaattat tattaagtaa
    21301 attaaagaag ttaaagcaat tgttggattg gagaataaat taattattac aactggtgcc
    21361 atacctatta ctggaccaaa atatggaacc atattcatga cacccataag tgtaccaaat
    21421 aatagtgcat attcagattt taaaaagtaa agaccaattc cagaaagtac tccaactata
    21481 aaagaatcta aaatcttacc tgtaaagtat ttaccaatat ttaaatttaa gctttgacat
    21541 agttctatta taaagtctcc atatttttta cctaaggaaa tataaactac tttttttgta
    21601 aacagtaaga atttttcttt ttctaataat atatagaaac aaattataaa acctaaaaga
    21661 aattgtacta taaattttcc aactgaaaat gtagtgctaa atatcccacc aagtgaacca
    21721 ataagcaagt tactaaattt aggcattaca ctcataattt tgtcaccata ctcttttaat
    21781 gtattagggt caactgattg taaactcttg cctaagtcga ataaaaactg ctctgtttta
    21841 tctatgtatg taggaatttg agcaactaaa tcagctaaac tatttactat ggatggaact
    21901 gtaaataata taaacgaaat tagtataact atgagtacac cataagtaag aagtaacgaa
    21961 tatattctct taaaatttaa tttactttct aagaacttta ctagtgggtt gaatatatat
    22021 gctaatacaa atgctattat aaatggtgtt agtagtgaca ttaataaact tatcactcca
    22081 aaaaaatatt tgtaattatc aataacttta atcaagatat atgaaacaac tacagtgagt
    22141 acaatattta gataaatttt tttatcttgc aaaataacac aacctttctt atatttatta
    22201 aatttagata tacttaaatc taagttaaag ttaatattta tagcttatta tacaataaaa
    22261 agcagtatta atatagtatg attaatatga aattataaat acgttaaaac tttatgttta
    22321 tagctaaaat aataaaaatt atttatattg tgtttatata taatctaaaa tgaaaaaaag
    22381 tggtgccttt gattaaacta agtttttata atttaaattt tgtacaataa gctatctttt
    22441 attattcttt aaaatatata tttcatttaa ttatgacaaa taaagataaa aattaaatat
    22501 tttagaggtg attttattta gatatagaat tttagaataa tactatacaa atgtattgta
    22561 ttattatttt tatatcaaaa atagtaataa agtctatata catttagaaa atactgttta
    22621 aaaggagtag gatttatgat aaaaaaagag atatctaact ttagaggaag tagtgattat
    22681 gtagtatcac cagaattgat ggcatcagtt aatgttgcta ttgctcttga aaagccactt
    22741 ttgattaagg gcgaacctgg aacaggtaaa actatgctag cacaagcaat ttcaaatgaa
    22801 ttaaaaaaag atttagtaat ttggaatata aaatcaacta caaaagcaca agaagggctt
    22861 tatgtatatg atactgttca aagactttat gatagccaat ttggaggaga aggtgtagat
    22921 gatattagca agtacataaa atatggtaaa ctaggagagg cctttagctc aaatcaacaa
    22981 gtaattcttt taatagatga aatagataag gcggatttag aatttccaaa tgacttgctt
    23041 tgggaattgg ataaaatgga gttttacata aatgagacaa aagaaactgt aagagctaaa
    23101 caaagaccaa tagttattat aacttcaaat gcggaaaaag aacttccaga tgctttttta
    23161 agaagatgca tatttcatta tatagaattt cctgatagag acatgatgga agaaatagtt
    23221 aaagtacatt ttgataaagt agaagaacac ctattggaac aagtaatgac tactttttat
    23281 tggattagaa gtttaaagga catacaaaaa aagcctagta catcagagtt aatagactgg
    23341 atacaagcat taactttgag tggaatgcct attgaaaaaa tagaaaaaga agttcctttt
    23401 gcaggaatac tacttaagaa taatgaggat attgaatcta tgcaaagaca cttatagtta
    23461 ataggagctg gataattatg tttattgaat ttttttattt attgaggtca agaggattaa
    23521 atgtatcttt aaatgaatgg atgactttaa ttgaagcatt ggataaagga ctgtgctatt
    23581 caaacttttc aaatttttac tatctttgca ggatgatttt aataaaaagt gaaagtgatt
    23641 ttgataagtt tgatgcagtg tttttggagt attttaaagg tatagaacac caagaagaaa
    23701 ttccagaaga gattatgaat tggcttaaaa aaccagatat agatttagaa gagtttgaaa
    23761 gattagaaca aaatccaaat ataaatcttg ataaattaag agctaaattg gaggaacgaa
    23821 taaaagaaca agattctcct cataatggtg gtaattattg gataggcaca ggaggcactt
    23881 cagagttagg acattcagga aaagggcaaa ctggtatacg tataggtgga aattctactt
    23941 atggtagagc tgttcttgaa gttgcaggag aaagaaaata tagagatttt agagatgatg
    24001 aagttttaaa tatgcgtcaa tttcaagttg cactaaagag acttcgtcaa ttttctacta
    24061 gaatagatgc tccaaagaca gagcttgatt tggataagac tattgaagag acttgtaata
    24121 atgcaggata tttaaagtta ttttttgaga agccaagaaa aaatacagtg aagcttttat
    24181 tgcttatgga ttcaggtggt tcaatgagag ggtatagcac tttatgtaat acattatttc
    24241 agtctgtaag taaatcaaat cattttaaag atgtaaagat atattatttc cataactgta
    24301 tttatgatag attatttaca acacctgaat gttggttaag taaatctatt aatactgaat
    24361 ggatattaaa aaatatagat aaaaactata aagttataat tgttggagat gcttctatgt
    24421 cgccttctga gttgcttcat attggtggta actatcgtgg tccatataat tacacacctg
    24481 gtatagagtg gcttaaaagg tttaagagaa agtacagtaa aattgtatgg atgaatccag
    24541 aacttagaga tggatgggat tcaattaatt attggtatca aactcaaaga atgatacaaa
    24601 gtgaatttaa tatgtttcca ttgactgtaa aaggtcttga gaaagcattg aaaaatttaa
    24661 tggtttcaag ataaagtaaa tataaatgat ggtatgattt attcaaaatt gtaccatcat
    24721 tatttatttt tttaatatac ctattataaa ttgtataact gaaacttaaa aaattatata
    24781 gtctaataca ttttagactc acacaaaaca tatacattaa taataatttt agaagtcgag
    24841 gtgattataa taaattatga attaattgta aaatacaatg gagatatatt gaggttagaa
    24901 gaagaattag gtgtatcagt agagatactt aattcatcat atgcaataat aacatcaagt
    24961 aatgaagaag atgtaaatat acttttaact tatccagaaa ttgaatttat agaaaagcct
    25021 tttatattac agactcagga tgtgcaaagt ttttcaagta caggaataac aggatttaaa
    25081 aatagaactg gtttaactgg aaaaggaact ataattggta taattgattc gggaatagat
    25141 tatactctac ctgtgtttag agatagtgat ggaaggtcta agatattata ttattgggac
    25201 caatctattc aaggaaatcc accagaaggt tttagagaag gaacattata tactaatgaa
    25261 gatataaata atgcaataga tggaagtatg tatataccta tttcaacaac tagcttacat
    25321 gggacacatg ttgcaggtat ttgtgcaact attgcaagtg atgccagaat aatagtggtt
    25381 agagttggaa atatacaaac cgatattttt tcgagaagta cagagtttat gagggcaatt
    25441 aaatttattt tagatagggc attagaatta agaatgcctg ttacattaaa tataagttat
    25501 ggaagtaatg aaggttcaca tagaggaaca tctttatttg aacaatatat agatgatatg
    25561 tgtttatttt ggaaaaacaa tatagttgta gcagctggaa ataatgcaga taaaggaggt
    25621 cataaaagga ttaggcttca aaataatatt acagaagaag ttgagtttat agttggggaa
    25681 ggagagcgta tattaaacat aaatatatgg ccagattttg ttgatgattt tagtgtacat
    25741 ttggtaaacc catcaaataa tcaaacacaa gcaatctctc taacttcagg tgagataagg
    25801 aatactttgg gtgaaactag aataactggt tatttttacc ctatagcacc gtattctctc
    25861 acaagaagag ttactctaca attaagttca aatacacaga taactcctgg gttatggaaa
    25921 attgtatttg aaccaataga tatagtaact ggtaatgtaa atatatattt gccaacttct
    25981 gaaggtctaa atagaaatac tagatttctg attcctactc aagagcttac tgtaacagtt
    26041 cctggaacag caagtagagt tataacagta ggtagtttta attcaagaac agatatagta
    26101 tctatatttt ctggtgaagg agatacacaa ttaggtgttt ttaaacctga tttattagct
    26161 ccaggtgaag atatagtatc ttttttacca ggaggtacaa gtggagcatt aactggaact
    26221 agcatggcta cacctcatgt tacaggggtt tgttcattgt ttatggaatg gggaattgta
    26281 aatggaaatg atttattttt gtattcacag aaattaaggg cattacttct aaagggagca
    26341 aggagattaa gtaatcaatc ttatccaaat aattcatcag gatttggttt tttaaattta
    26401 tcagatatag atttgtacac tctatctaat ataaatcaag atttagaaac agaggatatt
    26461 ggatatagaa gtattaataa gtcatttaaa gatgaggaaa atagttataa gtttatagat
    26521 ggttataata tgcaaataca taatgactta gagaatgaaa tttatataag taaaaatgca
    26581 agtagacaat caggaatact atcaggaata gatatagtcc atactcctga atttgaagaa
    26641 gaactagctg ggttaggtat gagtcaaagg ttttttaaga taagtgattc attaggtgta
    26701 ctatctataa ataatacaga ctataatagc atacaacgag ttttgcaact tccttcaatc
    26761 ataagaactg tatcgactac aaagatgaca ttacttggag aaattaatcg aggtactttt
    26821 ggaggtgtag ttgcaacaga agaaatgggc gtaaatttct ttaaaaataa tcctaatatt
    26881 aatataacag gaagagggac tctaatatca attgcagata caggaataga ctatctacac
    26941 ccagatttta tttatccaga tggcacttca aaaatagtat atttatggga ccaaacaaaa
    27001 gaaggaactc ctcctgatgg tttttatatt gggacagaat atacacgaga agatataaat
    27061 cgagctatcg cagaaaatga ccctagtcta tctcaggatg aagttggtca aggaactatg
    27121 ttgagtggga tatgtgcagg gcttggaaat gtaaatagtg aatatgcagg tatagcagaa
    27181 gattctgagc taataataat aaaactcggc aagatagatg atttttataa tagtgcaatg
    27241 ctgtttgctg catctcagta tgcatataaa aaagcttttg aacttggaag accattagtt
    27301 ataaatatgt ctttaggtac cagtagccta gcaggtttaa ccaataggag taatagtgaa
    27361 aaagcgttct ttactagagg gttatgtata acggcaggag caggaaatga gggcaataca
    27421 cagacacata catctggaat aataccatat gttggaggtt ctgttgaagt tgaattagag
    27481 ttaaatgaag atgaggaaga attatcatta gaactttggt taaatagacc agataaagct
    27541 gatgtaataa tagtatctcc cactggtgaa gaaagtaaaa gtgttggaat ttcaaattat
    27601 aataaagtaa caggtttatt tgatttagag gggactgaat attctataac atatatatac
    27661 ccaacaactt tttctggaca gcaatttact aatgttactt taaagaatgc aaaaagaggt
    27721 gtatggaaga ttcgattagt aggagtttat attataacag gaagatataa cttatacctt
    27781 ccaaatagag aacttttaaa aagtggaact agatttagag aggtagaccc tttttacact
    27841 ataaattatc ctgcgattca agatgattta ataaccatag gagcctacaa tactattaat
    27901 ggtagtttat ggcaaagttc atcaagaggg ccaactattg aagacaggtt aaaaccagat
    27961 atagtagcac caggtgttaa tataatagct gcttatcctg ggaacacgta tgcaactata
    28021 actggtacag cagcagcaag tgcacatgca gctggtgctg ctgcaatgta ttttcaatat
    28081 acttttgttg acggtagata tccaaaccaa gcatatgtgc aaaaaataaa aacttttatg
    28141 caagctggtg ctagaaaaga ttcaaacaca gtatatccaa atacaaattc tggatatggg
    28201 ctcttggatg ttagaggaat gtttgatgtt ttaagatagg agggatttat ggaaaaatct
    28261 tattgtataa tttatcaagg tgatatagaa tctgccctac aagaaaatgg aataaatagg
    28321 tatatggttt taaatagtca gcttgcagta atatatgtac ctttagattt tgatgaaact
    28381 attttaaata atataataca agttgcttgg tgggaagaat ctgaaccaat gagcagtcta
    28441 attgaaataa ctaataatgt aaataatgga gaaaccatta caacagcagc tgaaactgat
    28501 tatatttatg aaaatccata taatgatata acagggagag gaattttatt agcagttata
    28561 gattctggga tagattattt gcatcctgat tttataaatg atgatggaac tagtaaagtt
    28621 ttatatttat gggaccaaga agcaaataca aatccacctc cagaaggttt tatttttgga
    28681 agtgaattta caagaagtga gttaaatata gccataaata gaaatgatgg gagtttgagt
    28741 caagataata taggtactgg aactttagtt tctggtatat tagttggaaa tggaaggata
    28801 aattctcagt acagaggtat tactacagaa tcagacttaa tagtagttaa attaaaatca
    28861 tatacagata cttattatgc tggaaggata aattacagtg tttcagattt tttagcagct
    28921 ataacgtatg ttactaacat agcaagaaca gaaaataaac cactgataat aaatttgact
    28981 attggagtta agtcaagtgc tgtagcaact acttcaatac tagatacttt taatatattg
    29041 agtagtgctg gtgtggtagt agtgagtggt gcaggaaatc aagggaatac agatattcat
    29101 tattctggca gatttagcag tgtgggagaa gttcaagatg taataataca agatggagat
    29161 gactatgctc ttgatataac actaaatacg aatggtccag ataaagtggg agcacagata
    29221 atatctcctt caggtgaagt tagtcatgat ataaggtatt ctccagactt ttatatatat
    29281 agaggaaaat ttaacttaga aaatactact tatgcaatga gatttattta tccatatatt
    29341 acctctggaa aagaaaattt ggagataaga ttaagagata taaaacctgg agtatggatt
    29401 ttaagattga cttcagaact tataataaat ggagaatatg acatatactt gccaaataaa
    29461 aatttgatag ctccagacac aaggttttta gaccctgatt cagtagctac tataactatg
    29521 tatgctgcta gtgatgatgt aattacagtt ggtacattta acaataagac tgatagtatg
    29581 tggattggtt cttcgaaagg accaattaga ggaagaggaa ttaagccaga tatagtagct
    29641 tcaggtgtag atataatatc cacatataaa aatggaacat ataatacagg aacaggaaca
    29701 ggagtgagca gttctatagt cacaggtgtt ttagccttat tgatggaata cttagaaaaa
    29761 caggataatg taccgagatt atcattgttt acacaagttt taaaaacata tttaatattg
    29821 ggtgctacaa aacttgagat atatacatat ccaaatgtat cgcagggata tgggatttta
    29881 aatttaaaaa atacgattca acagatagca aatactctat agataagaac ctatgtaaaa
    29941 ttataattga ttattagttt aattgtatca aatactttag atagagtaga aaaatagcat
    30001 aaaaaataaa tatgaaaatt aaaaaacagt tttatatttt gaatacacaa agtaaatatt
    30061 ttgtatataa ataggtataa attaagtatt gaaaagatat gatgttaatt taaaaataat
    30121 tataatttag acttatgaat tttatttgta aaattgctaa aactattaca aaataaataa
    30181 tagaggtgat agttttggaa agtaaaaagg caagagcatt aaaaggtaaa gataataaaa
    30241 gacttaaaag ttcactttta gttggaaatg agtcgacagc agcatgggct gatgttgaaa
    30301 aattaaaacc tcatagtaaa gtttcaatac cttcaattaa gggtgtcgaa gaagcaaaag
    30361 actgggttga caatggaagt aaattataaa attttggaaa ttgaagtaat aaagaagtaa
    30421 tgaagataag tatttattat cattatgtaa ggtagaatta ttatatttta aataacaatc
    30481 agtatcaatt atataaattt attgactaaa aatttataaa ttggtataat tttgttaatt
    30541 agcagaaata ataaaagata aatactgtga agagaagagt agatataaaa tgtagttcta
    30601 gcgagttgag gatggtgaaa gctcaatacg aggtttatat tgaagaacat cttggagttt
    30661 ctaatcgaaa gcttatttag taagtagact tagacggaag gcaccgttat aggctttaag
    30721 cattgcttaa ctaagaggtc attatgacaa ctagggtggt accgcgagag taatagtctt
    30781 tcgtcccttt atatagggat gaagggcttt ttttattgaa attatattta aaagaaatta
    30841 ataacaatta tactaggagg atttaaaatg caaaaggaat ttataacagt aaaagaattg
    30901 tacagagaaa aagaacagta catagggaag actgtaaaag tagctggatg gataagaaca
    30961 tctagagtat ctaaaaattt tggatttata gagctaaatg atggaagctt ctttaaaaat
    31021 atgcagatag tatttgatga gaaagtagaa aattttaaag aggtaggaaa attagcaata
    31081 agctcatcta tacttgtaga gggagagtta gtatctacag aaggggctaa acaaccagtc
    31141 gaaatacatg caaaaagcat agttgtagaa ggggaatcag atagttcata tccactacaa
    31201 aagaagagac atacgcttga atatttaaga acgatagcac atttaagacc aagaagtaat
    31261 actttttcag ctgtatttag agtaagatca atagctgcct atgcaataca caaattcttc
    31321 caagaaagaa actttgtata tgcacattct ccaatcataa caggtagtga ctgtgaaggt
    31381 gcaggagaga tgtttagaat aacaactatg gatttaaatg atattccaaa aactgaagat
    31441 ggcaaaatag actatactca agatttcttt ggaaaagagg ctaatttaac agttagtggt
    31501 caattaaatg ccgagataat ggcactttct tttagaaacg tttatacttt tggacctaca
    31561 tttagagctg aaaactctta tacaggaaga catgcttcag aattttggat gatagagcca
    31621 gaaatagttt ttgcagacct tgaagataac atggaacttg cagaagatat gataaaatat
    31681 gttataagct atgtattaga aaatgctcct gaagaaatgg aattttttaa tagttttata
    31741 gataaaggat tgttagaaag gttaaataag atagtaaact ctgagtttat tagaataacg
    31801 tatactaaag cagtggaatt attaattgaa tctgggcatg aatttgagta tcctgttgag
    31861 tggggatgtg accttcaaac tgagcatgaa agatatataa cggagcaaat atataattgt
    31921 ccagtgtttg ttacagatta tccaaaagat ataaaagctt tctatatgag aatgaatgaa
    31981 gatggtaaaa ctgttagagc aatggattta ctagttcctg gagttggaga aatcgtagga
    32041 ggttctcaaa gagaagaaag agaagatgta ttgttagata gaattaatga aatgggatta
    32101 agagaagaag attattggtg gtatttagaa cttagaaagt ttggtactgc tactcactct
    32161 ggatttggtc ttggatttga aagaataatt atgtatatga caggtatgtc taacataaga
    32221 gacgttatac ctttcccaag aactcctaaa aatgctgaat tttaataatt atatataata
    32281 aaacttatat aactttaagt ataaacacta aaatgacttg catatttatc tattttagag
    32341 atatgcaagt tatttttatt gtactataaa tatataattt gattactttt attttgcgat
    32401 ataatactta taggtttatg taatagtatg taacctttta ataaaatgca acacaattac
    32461 gtccctgttc ttttgcagta tatagagcct tatcacaatt acttataaac tcatttaatg
    32521 ttattgtctt tccaattttc tttgtataaa ctccaatact aacagttaca cattttaaag
    32581 gaacatcatc acgctcaaaa ttgcaggact ctataatttt tcgtaaacat tctgatttaa
    32641 gtttagcatc tgcctcatta cagttaaaaa tacatataaa aaattcctca ccaccatatc
    32701 gtatagcatg ttcattttca gaacttgtaa aatctaaaat tactttggca atattttgta
    32761 gacaatagtc tcccttttga tgtccataat tatcattaaa ttgtttaaaa taatctatat
    32821 ctatcatcat tccagttata ggttcttgat ttgcatggct gattaatttt ttttgtagaa
    32881 tatcttcaag gtatctacgg ttgttcattt tagtaaggtc atctgtcata actttgtcgt
    32941 taagtaaatt atttatatga gatatttctt catattgttg actaattaaa agtttatcat
    33001 agtaagtaaa tacacgattt ctatatagca ttgtagaaac aaaaatggca agggatgtta
    33061 taaaaaatgt gttgacaata ttactaaact cattgcctgg tatagtttga atcccaggta
    33121 agaataaatt aagaaacaaa aagcatcctc caaaaactat tactgattct ccaaatttta
    33181 atactgagaa agctgcagct gctaacataa tataactaaa tacacttagg tcatttccac
    33241 ctaactggtc aagtagagta attacacaac cccataggca gaaaaaagtc acataaatta
    33301 tccataaatt tatataaaac gtacagcaat cctttttttt attccaaagg taagaaaata
    33361 caaacataaa gacagaagat acacaaaata gtgttacata catataaaaa taccattggc
    33421 gtcttggtgt gacaaaaggg cctccttctc tagctgagat tgatatcatc ataattattt
    33481 gagatattac tattattatg caaatgattt tacccgtatg ataaagataa ttgcagagtt
    33541 ctttctcaac attgtctttg tgttttttgt ctagaggaaa tccaaaaaat ttttttattt
    33601 tttctaagtt catataagcc tccattaaaa ataaagcata aaaataagta ttcctttcta
    33661 tcattagata tttggaatac ttcgtttatg atttaattat atcaaaatat attgtgtgta
    33721 acaatctaaa attgtgatag ataaaattta ttagataatg tcgagtaact ttattgatta
    33781 atactttatt ataattaaga tttacagata gtttactact gaaaataaag aatagaataa
    33841 atttaaatta agcataataa aatataaata ataaagttcg cattaacaaa ctatttaaat
    33901 atcaagacct gttaaaaaac aacagcaata aacaaataaa atagataaat atatccaatt
    33961 aaggtataat taagttttat atgatatagt tatatttgat aatttacaat agtaaaactt
    34021 ggagggaaaa aatgggtgaa aagaaaataa ataatatgaa ttattcacat aataattatt
    34081 ccaaaaagac aggtgaacca actagaaaaa taaaaaatag ccatatcact cttaaaagta
    34141 aagaagaaaa aatttgttct agttgcaata aagaaaataa tactaaggat aattactgta
    34201 aattttgtgg aaatgaactt tatgaaatag catcattaag accacttgaa acaaaactag
    34261 acttgaaatc taaaataaaa gagctttcat atcatgcaaa taaaagaggt gtatttttaa
    34321 caacatttac aaccatattt atattgttta ttattgcatt gatatttaaa gctattataa
    34381 ctattcaatt taatgatatt agttatttag taaatccagc acatataatc ctagctctca
    34441 acttgggtca aattagtgta tctatgtcta ccatgatggg ttctgggttt ataaatgcca
    34501 atataggttt gttgatatta cttataatcc ctattttggt attattaata tcaaacctaa
    34561 tttttatgag aaaaagatgt agagattcaa aaactgtatt agcaaattct ctaggagttg
    34621 gaatttttta tggattagtt ttagctattt tatctatttt tactaatgta aaaactagtt
    34681 cacatagtat gttagaatat ggatatgcat tagaatatag ttatgaattt tttagtgttc
    34741 ttttaaatgg attcgtatta gggtttatat gtacatacat aactacttat aaaaaaagtt
    34801 atgaaaaaga aaatatgtat ttatctcttt tttcaaattc tataagaaca ttcatattag
    34861 gttatgtttt agtattagta atactattgg tactaactat atctgatagt agttacttaa
    34921 atgaactaga tatgagtagt tattcaaatg gattaaattt atttactata ctcccacaaa
    34981 tagctagtta tatgtgggct tttgcaaatg gaatttcagt aaccataata aactcaacag
    35041 tatcaatgtt tactttaagt tcttcatctt tatttggaga tactaaatta atgttttatg
    35101 caatgggagc attgtctatg ttaatattat tattaaatgg atacaagcta agatttaagt
    35161 ataatacaga tagtataaga cctataatag tatttagtat atattatgca tttttgatgg
    35221 gaatattggc cttatttagt acatttatac tagatagtaa tattaatttc tttaatacaa
    35281 ctaattatgg aacaacttta ataatgcaat ttaaagtctt acaagctatt gtaatttcat
    35341 ttgtatatag ttttgtgata tctttaatag gatataagct aaattcagct gattaaatat
    35401 gattggaggg aatttctgtg gaaggaaata ctaataataa agtagatgat aaattttcta
    35461 aggttaagaa aaagtttggt agtggaaaat ttaaagttga attatataaa gaaaaatcaa
    35521 aattaaatag agagattgat gatattcaag aaaagaaagc aaagatattc ttggaaatgg
    35581 gaatactgac atatcaaaaa attagagaag attctattaa tgataatagt tttgataaat
    35641 tctgtgatga gttactagaa cttgataagt taatttatga aaaaaatatg gaaattaatg
    35701 aaatggaaat ggcagaaagt aatgtaactt gtgagtgtgg ttatgttgga aatgtaaatg
    35761 ataaatattg tgctgaatgt ggtaaaaaat ttgaattgga aaatgaatgt gatgatttta
    35821 taatttgtgg ttattgtgaa agtgagatag atacagaggc tgaattttgt ccatgctgtg
    35881 gaagaaaaat tataatggat ttagaataat attgggaaac ctatgtatag tatacatggg
    35941 tttttttatt gaaattattt aaatggactt ataacagtag ttatataaaa tgaaaataaa
    36001 caccaaaaaa atgaaataaa atttctttta aatgtaaaaa acaagctaat atataaaata
    36061 aatcagtaaa aatatagatg cgagaaaaaa tatgaaaaaa tattgcaaag aaaaagtttt
    36121 catgttatta ttaatacata aatcaagaaa ataaatttca gaaacgaggt aatttaaaaa
    36181 atgctagata aggtaaaggg aagattaata gtatcatgcc aagctttaga aaatgaacct
    36241 cttcatagtc cttttataat ggggagaatg gctaaggctg ctatggaagg tggagctgtt
    36301 ggaattagag ctcaaggagt tgaagatatt attgaaataa aaaaagttac tggacttcct
    36361 gttataggta ttataaagag aaactatgaa gattcagata tatatataac gccaactaaa
    36421 aaagaagttg atgaactttt aacaacaggg tgtgaaatga tagcattaga tgctaccaat
    36481 agagttagac caaataatga agacttaaaa gaacttataa agtatataaa agaaaacggt
    36541 gttctagtaa tggcagatat ttcaaattat gatgaggcta tcaaagcaca agagtacggt
    36601 gtagattgcg tttcaactac actatctgga tatactccat atactaaaac attagaaggt
    36661 ccagattttg tattaatgaa aagattagtt aaagatttag aaatacctgt aatagctgaa
    36721 ggaaaggtaa atactcctca agatttaaaa aaggtctttg agttgggtgt tcattcatca
    36781 gtagtaggtt cagcaataac aagaccacaa ttaataacag aaaaatttgt taaagcaatt
    36841 gaaattaatt aaaaattaat ttataaatta aaaaattatt atatttaact atatttgaaa
    36901 attaaaattg gaggtaaaga tatgagaaca acagatatga agggaattta ttcagcatta
    36961 ttagtttcat ttgataagga aggaaatata aatgaaaaag ggttaagaca aataattaga
    37021 cacaatatag atgtttgtaa agtagatggt ctttatgtag gaggaagtac aggggaaaac
    37081 ttcatgcttt caactgatga aaagaaaaga atatttgaaa tagctaaaga tgaagtgaaa
    37141 gaagaaataa aattaatagc tcaagttggt tcagttaatt taaaagaagc tgtagaactt
    37201 gctaaattta caactgattt aggatatgat gcaataagtg ctgttacacc tttttactat
    37261 aaatttgatt ttgaagaaat aaaacactat tataatacaa taataaattc tgtagataat
    37321 agattaataa tatactctat accattttta actggtgttg atatgagttt agaccagttt
    37381 ggagaattat ttgaaaatga aaaaataata ggtgttaagt ttacagcagc agatttctac
    37441 ttattagaga gaatgagaaa aacattccca aataaattaa tatttgcagg atttgatgaa
    37501 atgatgttac cagctacagt tttaggtgta gatggggcaa ttggttctac attcaatgta
    37561 aacggtgtca gagctagaca aatattcgaa ttaactaaga atgaaaaaat atcagaagca
    37621 cttgaagtac aacatgtgac taatgattta ataacagata tattaggaaa tggcttatat
    37681 caaacaatta aattactact tgaagaacaa ggtgttgagg ctggatactg tagacaacct
    37741 atgaaagaag caactgatga aatgaaatca agagcaaaag aaatatacag aaagtatttt
    37801 taataaaata cttttagtat gggaggatta gtcaaatggt aggatttact tggatagatt
    37861 ttgcaatact agtggtttac ttattggcag ttttatttgc aggattgtta ttttcaaaaa
    37921 aggaaatgaa gggaaaagag ttcttcaaag gtgatggaac tattccgtgg tgggttacat
    37981 cagtatcaat atttgccaca ttattaagtc caatatcatt tttatcatta gcaggaaatt
    38041 cttatggtgg tacttggatt ttgtggtttg cacaattagg tatgtttata gcaatacctt
    38101 tgacaataaa atttttctta cctctatata gtaggttaga aatagataca gcatatgaat
    38161 acttagaaat gagatacgaa agtaaaggtc ttagagtact tggagctttg atgtttataa
    38221 tatatcaaat aggacgtatg tctattataa tgtatcttcc atcaatagtt ctggctggtc
    38281 ttacaggaat acctgtaaat gtactgataa tagttatggg tgtaatagca ataatttact
    38341 catatacagg tggattaaag gctgtcttgt ggaccgattt tatacaagga atggtattaa
    38401 tagtaggtgt tacagggaca ttgttctatt taatagcaag tataaatggt ggttttggaa
    38461 cagtaatgga tactcttaca actggacaca agttcttagc aagtaatgaa gttatgtttg
    38521 ataaaaatat actatctaca agtgcattta taatatttgt tggagctggt cttaatactt
    38581 tttcatcata tgtatcgagt caagatatag ttcaaaggtt tactacaaca actgatataa
    38641 agcaacttaa taaaatgaca tatggaaatg gtgttttatc aatgggactt gcaacagtat
    38701 tttatctaat tggaacttgt ttatttatat actatactca aaacccagat ttagctcaaa
    38761 cagttcaaca agaccaagta tttgcatcat atatagctta tgaattacca gtgggtataa
    38821 caggaatact acttgcagcg atatatgcag cttctcaatc aactttatcg acagggctta
    38881 attcagttgc tacaagttgg actttagata tacaaactat cataacaaaa gatataagta
    38941 tggaaaagca aactaagata gcacaatata tatcattagg tgtaggtata ctttctatag
    39001 ctgttgcaat agtattagca aatggagaaa taaagtcagc atatgaatgg ttcaatagtt
    39061 ttatggggct agtactaggt gttttagcag gaatatttgt acttggtgca ttttgtaaaa
    39121 aagcaactaa aatgggagca tatgttggat tcatagtatc agcaatttta gttgtttatt
    39181 taaaataccg tatgccagaa gtaacttctt gggcatattc tctaataaca atcacgactt
    39241 ctgtagtggt aggtacaata gttagtgcaa tagaagctaa agttaaagca aaagtatctt
    39301 taccaaaagc tgagactact gtttattatg aaaaataata tttaaatgat aaattgtctt
    39361 atagagtgat tagataaata atttagttac tctataagat tgtataatat actttgtata
    39421 caaaagtata aaaatagact ttataattat atagggagat agtgcttatg atatttggaa
    39481 atataaatca tagtaagaca tattcaacat tgcatgaaga tttacttaga tgttttgaat
    39541 atgctaaaga taattcatta atagattatg aaaaaggtac ttatacaata gatggtgatg
    39601 atatttttgt gaatattgta gagtataaaa cttgtgaaaa agaagataga ttctgggaag
    39661 ctcataagaa gtatatagat gttcatttga tgcttgatgg atgtgaacga atagatataa
    39721 attttataga aaatttagaa caaaaaatat atgaagaaaa gggcgatttc ttgcctcttg
    39781 atggtaaaaa taatggatac atggaactta gaaaaggtga ttttttagtt tgttatccgg
    39841 aagatgctca tatgacagga ataaaagttt tagaaaaaga aaatatcaaa aaagctattt
    39901 ttaaggtttt ggttagataa tgataattta tataaccact agggctgaaa atagtgattt
    39961 aactttcagc gattagtgag acttcgtaaa ttttagttag attactattt tcagccttag
    40021 ttttttatga gaaaattaaa aataattaaa agcttaaaat tttgtaaagg agttaactta
    40081 tggaaaatat agatgtattc ttattaatag gacaaagcaa tgctagagga ttgggaaatc
    40141 caaaagagag catcattcca aatgaaaatt gttttgaata tttgagtact gatgaaatta
    40201 taaatatgag atgtgagcta gagacttcag aaggtgatgg tactatagca cctgcatttt
    40261 caaatgaatg gaataagctt actggaaata aagtttgttt tattcacaat gcaaaagatg
    40321 gttcaagaat aaaaaactgg aatcatgata ataactggtt tctaaatgac actatagaaa
    40381 aatttaatac aggctgtact accttaagta aacattataa tatagaaaat aaatacgtta
    40441 tttggattca aggtgaaagt gatgcaaaat atggtagtga tgtattgtac tataaagaaa
    40501 gtctaaaaaa aattgcgtat aggcttaaag aagaatgtat gattgataaa atgtttgtaa
    40561 gtttaactgg ttattggctt ggagaagatg aatattttat tagaacaaga cgaattgcag
    40621 cagcacagga gtcggcttgt agtgaatgtg atatattatg tgtaggaagc aaaattgcta
    40681 tgcagtttca tgacagagga ttaactattg atgatgttca ttacactcaa gaaggtctta
    40741 atatgttagg agaggactta tgtaaaaata tttataagta tcatataacc aaagaaaaaa
    40801 gtgtattaag tgatactata gacttatcag aagcaaggaa atatatctgt gaattggaaa
    40861 agataagtaa aagatttgtg taatataaaa ttttaaatag agttgttaat ttataaaaat
    40921 aatttgtatg gagatatgtt atgaaaaatt acgtttgtat agatgttgga ggtacttcaa
    40981 taaaatatgg ttttattaga gaagatggat ttataattga taaatcaagt cttgatactg
    41041 aagcaaagga aaaaggtgga gaaggaatat tagccaaaat aaaagatata gtaaaaaaat
    41101 atatagagga aaatgaaata agtggtatat gtatatcaac tgcaggtatg gttgacccag
    41161 ttgaaggtaa aatactattt gcattagaag aattaattcc aaactataag gacatgcaat
    41221 taaaaaaaga agtagaaaaa gagtttaata taaaatgtga agttgaaaat gatgttaatt
    41281 gtgctggact tggtgaaatg tggcttggag caggtagagg tgcaacatct tctatatgtt
    41341 taacaatagg tactggaatt ggtggatgta ttataataaa taataaactg ataaatgggt
    41401 ttagtaatag tgctggtgaa gtaggatata tgaatgtaaa tggaagttct tttcaagaat
    41461 tggcatctac tagcagtcta attaaaaaag tagcaaaaat aaaaaatttg aatgaaaatg
    41521 acttaaatgg aaaaataatt tttgatttag caaagaataa tgatgaagat tgtttaaaag
    41581 aactcgataa tatgataaaa tcattagcag ttggaatcgc aaatatatgt tatgtaataa
    41641 atccagaagt ggtaatttta ggtggtggga ttatggcaca agaaaagttc ctaaaaccaa
    41701 aaatagacaa agcattaaag gaggttctta tagagagagt ttacaaaaac actaatatag
    41761 aatttgcaaa gagacaaaat gatgcaggaa tgcttggagc attatataat tttttaaaca
    41821 aaatataaag aatagaaggg tttttaatga gtattttaga acaattggaa tcaccaactt
    41881 ttaaagtcac aaaatcagat aaattattaa tagcttatat aaaagaaaat atagatgatg
    41941 tattttataa accaatatca caaatagcta aagagagcaa tattggtgaa gcaactataa
    42001 ctaggtttgt aaaaaaaatg aattttaatg gattacagga ttttaaagtt actttagcac
    42061 aagaaatatc aactatcaat aaaaaaaata ttataaataa aaatatacaa aatgatgagc
    42121 cagctttgga tacagcaaaa aaacttttaa gttcaaatgt aaccacttta gagaacacag
    42181 tagagataat caatagtaag gatgtacatg actgcgcaag gcttataata aatgcaaaga
    42241 aagtttactt cataggtatt ggatattctg gtataatagc acaggattca aactataaat
    42301 ttatgagaat aggtcttaat tgtgtaagtt ttgacagtag tcatacaatg ataatgatgt
    42361 cttccataat ggaagaagga gatttaataa ttgcaatttc acattctggt gaaacagagg
    42421 agattataaa aactgtaaag cttgcaagag ccaataatgc taaaattata tcaattactg
    42481 aaaataaaaa ttctgaatta aaggatattt cagatgtaca cttatcttat gtatcgggag
    42541 aaacagtact ggaaaccggt tcaatatctt ctaaattagc acaatttttc attattgatt
    42601 tagtatatac acaggtagta aaagaacttt ctaatgaagc tattgaaagg aaaattaaaa
    42661 ctacaaatgc tataaaattg tttaaaaatg aataaaataa gaaatttgta atgttttata
    42721 gagctctctt aaaaatttag gaatggagag atattacatg tctaaattaa aagattataa
    42781 tattgataaa gtaataattt ttaataattt aagtactaaa acgaagaatc aacttaaaga
    42841 aaaagttaaa ctaaaaagat tacaaaaaaa agaaatttta ttttatgaaa aagatagctt
    42901 agacagtgtt tatatacttt tagaaggaaa ggtatctatt tttaagataa gtgaaaatgg
    42961 agagagaaaa gtaattttca tattaaatag tggggaagtc ataaatgata ttacacttga
    43021 cgcttctaaa aactctactg ttggctgtga agcatttgaa aattcaattg tagcttatta
    43081 tagtattgaa gaatttttag aaattatgca aaatgatttt caacttacaa aggatattat
    43141 ttcttatatg gaaagaagaa taagacgttt atatagacag ttgaaaaatt ctatatctat
    43201 aaaagtagat aaaaaacttg cagcaaaatt atataggtta agtagagaat ttggagtttg
    43261 ctgtggagaa tggactttac taaatgtaaa tattacagtt acatatttag ctgatatgct
    43321 tggctgtaaa agggagactg tttccagaat gataaaggta ttgcaaaaag aagaacttat
    43381 taaaattgac aataaaggtt tttatgttaa agaaactgaa ttatcaaggt attttaaaaa
    43441 taattaatta tgattaagta agagtattat tagaatttta attaaataaa aatattatta
    43501 agagaatcta tttatagatt cttttttatt gtctaattta ttaattttta ttttacccta
    43561 ttgaattgta taaaaaaaca aataagattc ttttttattc aaaaaactta ctaaattttt
    43621 gattatcttt tcataagttg gtaaatgccg atatatcccg tatttgaggg ctttatcggt
    43681 attttctttt tggaagatac cttgcataag ctggcattta ccagcatgaa aatgcaacca
    43741 aaagtagtaa atgagtagta aatatacgtt ccgatattaa caagccagtc tttccagttc
    43801 tgcttttgca gattggaatg taccgtgtgc gtagtagcca agcgtcatgg ttatgttagc
    43861 gtgtcccatg agatattgca gggtgttcgg gttcattccc ttgtttgcca tattcgtaca
    43921 ataggtatgt cggaatgaat gtggtgtaat gtttggtaac ttgtctttgt ggtatttgtt
    43981 atacttctta atcagtcctc gtaccatacc cacatagttt ccagcgactt taggcaatcc
    44041 ctcacggttt aagaatagga aattgctgta accaccaaca accagcggtt gagcttttac
    44101 tctgttcttt agtattcttt ggagtgcttg ataagccctt tccgtcaatg gaatttttcg
    44161 ttttccgttc tttgtttttg gagtgtcaat atagtagccg atttcgctat ctcttaatag
    44221 ctggtggtct atattgagta ttctgttctg catatcaata tgcgttgtca gtccgcaaaa
    44281 ttcagaaata cgaagtcccg tttccagaag aagcacaacc tcatcataat acttgctgta
    44341 aatcttatcc gtttccataa aggcaagcag gcgttcttcc tgctctggcg taagaataac
    44401 tttcggctcg gtatcatctt ccagaacatc acttagctta aattcaaacg ggttctttct
    44461 gatacagtcg tcttgtatcg ccatataaaa tgacgctttc aaggaacgct tatagttgtc
    44521 aatcgttttg taggcatatc ctctttcact cattctgata gcccactctt tagcgtccga
    44581 ctgtttgacg gtatcaatcg ctctcatacc caatgggtca tttttcagag cgttcataag
    44641 atactgtcgt cctttttccg tagctcgctt gatgttcttt ctttggctgt tcttcttgtc
    44701 gtaaagctgg cagactgtca ttttaccgcc tgccgtgtca ataccgtcat caaggtcttt
    44761 ttttatctgt gcttcttttt ccctcaacga tatatcatca cgttttccag caggcgtttt
    44821 gtctgtcggt acaagtttcc aagcataaat aaactgtggc tttccgtata tatcggtata
    44881 tttataaacg tatcttccgt cttttcgctg gctctctcca ttacgcaaat tgcgattttt
    44941 actgtctttt cgtttcacat tagacatagt gtaaagctcc tttccgtcat ggaatgagcc
    45001 gtgatacgct atacttatta taccatatcc acggctctat gacattagat ttcgtccaat
    45061 gtatctatga ttttttcaaa ttgttttcgc tttatctgaa tacggttgcc gttcacgata
    45121 acccagccag cgtcaatatt ttcttcggct aatttacgca acttcttttc tccaatgcgg
    45181 aagtatttgg acgcttcttc aatcgtcagt gtatattttt cccagatagg cacatcagta
    45241 ttattcataa tttatgcacc ccctttactg tgtgtcagtc tataagttat ataaacaggc
    45301 agacggcttt ggaaagctcc attagtattt caactattcc cattcttgtg ggcagaaccg
    45361 caccatgcgg aagtatcatt atgctgtaag ggtaggtcat ggcaaaacga cttttccaac
    45421 ggtcgctctc ggatcactgc gtgggtcgct cgctttcttt tggaaaggtc atggcgtaca
    45481 gttcccgtgg ctctctatcc ttacaaacgt atctgtctgc tttattcagt tttcaaagag
    45541 ctgtggcgaa agcggtatgc tttcatgtaa aagcaggagc agagcaggaa agaggggatt
    45601 gaacaaatca tgctctgcgt tactgctggt tattcttctt caatttctaa ggcaatatca
    45661 aaccctaaaa tcattttgat aagtgcttct cggataagtc cttttaactc catatctaca
    45721 acgatataaa cattaccgta ttcatcatag agtggacgca aacagcactt cgatatgtaa
    45781 gggtcataaa atgcaagtac cttttcaatc gctttttcgt ccccgtccat agcttgtgaa
    45841 agcaagtagt aagacggctt cttaaatgtg tgtttcattt gctatcgttt ctcctttaat
    45901 agttttctca taagtgccaa tgaattgtgg cggttctgaa aaactccgct tctggaaatg
    45961 ttttgctttt tggcgatttc ttcattgttc atttccaaaa agtaatacat caacaaagtt
    46021 tctcggttac gttcggataa ctgtttcaag gcttctgcca attcatcatc atagacacga
    46081 atatcattac cgcatacatt gaaaatcgta tagtctgttt cgtagtcgtc ccatacagcc
    46141 aagttttcaa ccatgatttc tggaagttca caaaaggaaa tttctttttc ttttcttcgc
    46201 ttcaatccct gctgatagtc cttgacaaca tgacggacaa ctttcttcaa acagctttca
    46261 aaacggcatt gaacagtttt ctggaagtca gacggtttca tcaatctcac cccctttccg
    46321 ttatgacgtg aaaagtgttt atccctcttt ccgcaccata tagggaatgg caagtgtgat
    46381 ttgttaagtt gaaaccagaa aaaatcgaaa aaacttttta gtaaaacaaa aacagcccgt
    46441 gtgaatgtga atacacaaac ggactgcttt ataaatgcta tctgtatgaa tttttaactc
    46501 ttgtagaggg tagaatgatt gtaatactga actaaaatat tttttcagtt gggaacagca
    46561 aagtattatt ccatatacaa tcatggcgta gcccccttta ccagagctat accttgtgcc
    46621 accaatgaaa aaggacggct ctggctatat ccaaaaccgc cccgttatgt tttcaagacg
    46681 cacaaaagta tatcatctcg gaacggttat ggtgatttaa aatgagaaaa acaaaagaaa
    46741 cacatacttt tgatttcaga ccgctagggc tggcaatcag agaagcccgt gaaaaagctg
    46801 ggctttctcg taatgattta ggcgataagg tattctatgg ggaa
//
LOCUS       DAGQVA010000022        46348 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.022, whole genome shotgun sequence.
ACCESSION   DAGQVA010000022 DAGQVA010000000
VERSION     DAGQVA010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46348
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.022"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            391..3939
                     /locus_tag="MIV85_001432"
     CDS             391..3939
                     /locus_tag="MIV85_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBY2960778.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            4124..6058
                     /locus_tag="MIV85_001433"
     CDS             4124..6058
                     /locus_tag="MIV85_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBY2960779.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6164..7159
                     /locus_tag="MIV85_001434"
     CDS             6164..7159
                     /locus_tag="MIV85_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2960780.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7131..7916
                     /locus_tag="MIV85_001435"
     CDS             7131..7916
                     /locus_tag="MIV85_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBY2960781.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7904..8602
                     /locus_tag="MIV85_001436"
     CDS             7904..8602
                     /locus_tag="MIV85_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960782.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8725..9198
                     /gene="ybaK"
                     /locus_tag="MIV85_001437"
     CDS             8725..9198
                     /gene="ybaK"
                     /locus_tag="MIV85_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBY2960783.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9395..10234
                     /locus_tag="MIV85_001438"
     CDS             9395..10234
                     /locus_tag="MIV85_001438"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBY2960784.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10247..10795
                     /locus_tag="MIV85_001439"
     CDS             10247..10795
                     /locus_tag="MIV85_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBY2960785.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10861..12042
                     /locus_tag="MIV85_001440"
     CDS             10861..12042
                     /locus_tag="MIV85_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBY2960786.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12337..12723
                     /locus_tag="MIV85_001441"
     CDS             12337..12723
                     /locus_tag="MIV85_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2960787.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12873..13136
                     /locus_tag="MIV85_001442"
     CDS             12873..13136
                     /locus_tag="MIV85_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBY2960788.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13265..14107)
                     /locus_tag="MIV85_001443"
     CDS             complement(13265..14107)
                     /locus_tag="MIV85_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBY2960789.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14402..15136
                     /locus_tag="MIV85_001444"
     CDS             14402..15136
                     /locus_tag="MIV85_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2960790.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            15146..16279
                     /gene="nagA"
                     /locus_tag="MIV85_001445"
     CDS             15146..16279
                     /gene="nagA"
                     /locus_tag="MIV85_001445"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBY2960791.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            16378..17127
                     /gene="nagB"
                     /locus_tag="MIV85_001446"
     CDS             16378..17127
                     /gene="nagB"
                     /locus_tag="MIV85_001446"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBY2960792.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17302..17574
                     /locus_tag="MIV85_001447"
     CDS             17302..17574
                     /locus_tag="MIV85_001447"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960793.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18234..18938
                     /locus_tag="MIV85_001448"
     CDS             18234..18938
                     /locus_tag="MIV85_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960794.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18940..20427
                     /locus_tag="MIV85_001449"
     CDS             18940..20427
                     /locus_tag="MIV85_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960795.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20632..22245
                     /locus_tag="MIV85_001450"
     CDS             20632..22245
                     /locus_tag="MIV85_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBY2960796.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22608..23438)
                     /locus_tag="MIV85_001451"
     CDS             complement(22608..23438)
                     /locus_tag="MIV85_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2960797.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKSACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23511..25238
                     /locus_tag="MIV85_001452"
     CDS             23511..25238
                     /locus_tag="MIV85_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960798.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FIYDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25275..27137
                     /locus_tag="MIV85_001453"
     CDS             25275..27137
                     /locus_tag="MIV85_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960799.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27470..28159
                     /locus_tag="MIV85_001454"
     CDS             27470..28159
                     /locus_tag="MIV85_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBY2960800.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28255..28941
                     /locus_tag="MIV85_001455"
     CDS             28255..28941
                     /locus_tag="MIV85_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBY2960801.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            28958..30865
                     /locus_tag="MIV85_001456"
     CDS             28958..30865
                     /locus_tag="MIV85_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBY2960802.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKHSGNQSDEKEVNAELTSSVVKA
                     NTDNENKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31317..32006
                     /locus_tag="MIV85_001457"
     CDS             31317..32006
                     /locus_tag="MIV85_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960803.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADN
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32442..32981
                     /locus_tag="MIV85_001458"
     CDS             32442..32981
                     /locus_tag="MIV85_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960804.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            33000..34043
                     /locus_tag="MIV85_001459"
     CDS             33000..34043
                     /locus_tag="MIV85_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960805.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            34045..34881
                     /locus_tag="MIV85_001460"
     CDS             34045..34881
                     /locus_tag="MIV85_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960806.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            34986..35660
                     /locus_tag="MIV85_001461"
     CDS             34986..35660
                     /locus_tag="MIV85_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960807.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35660..36712
                     /locus_tag="MIV85_001462"
     CDS             35660..36712
                     /locus_tag="MIV85_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2960808.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            36942..37790
                     /locus_tag="MIV85_001463"
     CDS             36942..37790
                     /locus_tag="MIV85_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2960809.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37780..39444
                     /locus_tag="MIV85_001464"
     CDS             37780..39444
                     /locus_tag="MIV85_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBY2960810.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            39493..40749
                     /locus_tag="MIV85_001465"
     CDS             39493..40749
                     /locus_tag="MIV85_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBY2960811.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            40772..42853
                     /locus_tag="MIV85_001466"
     CDS             40772..42853
                     /locus_tag="MIV85_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBY2960812.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSMKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            42890..43975
                     /locus_tag="MIV85_001467"
     CDS             42890..43975
                     /locus_tag="MIV85_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBY2960813.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGFVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            44029..45153
                     /gene="wecB"
                     /locus_tag="MIV85_001468"
     CDS             44029..45153
                     /gene="wecB"
                     /locus_tag="MIV85_001468"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBY2960814.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGMQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            45231..46205
                     /locus_tag="MIV85_001469"
     CDS             45231..46205
                     /locus_tag="MIV85_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBY2960815.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        18505 a         4683 c         8016 g        15144 t
ORIGIN      
        1 gtttaaattt tatgtataca aaattaattt gctaactgaa tcatataaaa aaaaacaaaa
       61 tattttttag agggaatgat tagatagaat ttttttgtta tgaaattaat tgaagagtaa
      121 ttaattagaa aaggaatgaa taataatgaa tatattacat tattactttt tgataaatca
      181 aaaataaagt tataattttt aatattaatt aagaatgatg aaatatgaat aaagatttta
      241 caaataaatc ttaagctatc ttatttaatt ctaatacagg aagaaggtaa atgtatattg
      301 aaaaaatcat agaaatagaa gtaaacaatt taaataaata caaaggtttg caaaagaagt
      361 aatataatta tatacaatga ggatgtgagt atgatgaaca gactaaagcc aagaatttta
      421 ggtattagta tcttgtttat tattataatt attttaacat gtggagctgt tttcaagttt
      481 aaatttaaat tagataataa attaaaagaa accacacata catatttgtc tgagtttaca
      541 gaacacaata taattaatct caagacaaga cttagtggtc aatttgacat gcttgaatct
      601 attgctaact tcataggaaa cttgaataat ataaatgatg aaatggtgat tgatttaatg
      661 gattctgatg taaagcgaag ttctttaatt agaatgacta tctctacatt agatggggaa
      721 tgttattcta atgatggaat tacccataat gttcaagata gagattattt taaaaaagct
      781 aaaaatggag aaaagaatat atcagagcct ttaaaatcta ttgttaataa taaagaaata
      841 atagttttat ctaccccagt ttataaaagt gggaaaatag ttggtgtttt aagtggaatt
      901 tatgattcaa aaaagttaaa tgagttatta ggattatctg catttgatga aaaagcagat
      961 gtttttgttg caaagaaaaa tggagatata gttgctcaaa aaacaaataa aaatagaaag
     1021 acgctatcat gtatatttca gctttttgac aaagataatt gtgatgaaga tgattgtcta
     1081 aaaactataa aagaaaatat gaaaaatgat aagtctggat attttaatta taacttagat
     1141 aatgaaaaat ttatgttaaa ctatcagcca cttggagtta atgattggta tgttttttct
     1201 gttgtgccaa ataaaatagt atctattcag tcagagaata tatcttatga tgtatatatt
     1261 tttgcattag aaatactact agttatattg atttttataa tatatatagc atgtattata
     1321 aataataaca ccaaaattat tataaatgaa aaagaaaaat ttaaagtact cactgataat
     1381 atattaggag gggttaaaac ctgtttaaaa gatgaatata tgactatgac atatgtaagt
     1441 caggggtttt tagagcttac aggttactct tgtgaagatt taaataaaat atttaaaaat
     1501 agatttaaag acatgattta taaagatgat ttagacaagt ttaattgtat tattctaaat
     1561 caattagaaa aacaagataa aattgaagtt gaatatagaa ttgtaagaaa agatggaagt
     1621 ataatttgga ttttggagag aagtaagtct ataaatgata ataaaggaag tgagtgtatt
     1681 cagggagttt taactgatat aacagaactt aagaaaatac aagaagaatt agattcaaaa
     1741 agatttgaaa tacaggctat caatgatagt attgttggtg gaatagtgat aactgagata
     1801 aatgatgatt ttgatagtat atatttaaat gaaggttatt taaatatgat tggatataca
     1861 cgcaaacaac tggaagatga gctaaataat aaattaatca aacttatttt taaagatgat
     1921 agaacagaat taattaatag tataaacaaa caactcaaat taagtgatac atttgcatct
     1981 gaacaaagag ttgaaaaaag ggatggcact attatatgga ttttattaaa aggaagaaag
     2041 atgatttatg ataatggaaa atctgtactt tgttgtgtta ttgtagatat tacttctgct
     2101 aaattattag agcaagaact taaaaagagt gaagaacgtc atgaaatcat tctaaagcag
     2161 acgcaaaata ttataataga atgggatata gaaaaagata aaatgaatat atcacctaat
     2221 tggtataata agtttaaata tgaccctata actgaaaacg caacaaaaaa tataattaaa
     2281 tcagtagata tatatcatga tgatatggat aagtttattt cattaattaa acttacttca
     2341 caaggtagtg agtatgaaga gtgtgaaatt agacttagaa ctagagatac tatttacgct
     2401 tggtttagta taaaggcaac aactttattt gataataatg gtaaacctta taaagtagta
     2461 ggaagtttga ctgatattga tgaatcaaaa cgagaagctg aaaagttgaa agaaagggca
     2521 gaaaaagacc ctcttacaga tctgtataat aaaaaagcat cacaatcact tatagaggag
     2581 tacataacat tggataaaaa aagaaaaggt gctttaatga ttattgatat tgatgacttt
     2641 aaaggaataa atgataattt aggacattta tatggggatg ctgtattaag tgaaattgca
     2701 aatgacctaa taaatctatt tagagcaacc gatatagtag gcagaattgg tggagatgag
     2761 tttattgtat ttataaaaga tatttctgaa acaagagata ttataaataa agcagaagaa
     2821 ttggtaaaaa catttgaaag gtctttttta ggtaaaggac gaaattataa aatatcatta
     2881 agtgtaggaa ttgctaagtt tccacaagat ggtatggact atatgacact atttagaaat
     2941 gcggatatag ctctttactc agccaaaggg aagggcaaga attgttatac attgtatgat
     3001 aaaaaatttg ataaagtcca atatataact aatacaagaa atgcaggaga tagtgataat
     3061 gtagagatgt cttttaaaga acatatcaca aattatatat ttgatatact atatgaatca
     3121 agtgatatag aagtggcagt aaatttaatt ctaagtattg taggtaaaca ctttaatgtg
     3181 agtcgcatgt atatatttga aaattcagat gataatcgag tatgtaaaaa tacatttgaa
     3241 tggtgtaacg aaggtgtaac ctcggaaatt aataatctta aaaatatttg ttacaaggat
     3301 ttaggcaact atcttttaaa ttttaatgca gatgggttat tttattgtaa tgatattgaa
     3361 aatttaggta gtgatgtgaa aaaagtactt aagccacaag gcatacgttc aatattacaa
     3421 tgtaaaattt tagagggtaa tgaatttaga gggttcatag gatttgatga atgttcatat
     3481 aatcgtatgt ggactaatga tgaagtgaac actttgacat ttatatctaa aacgctcagt
     3541 atgtttttat taaaaatgcg tattcagagt aagctagaag agtctttaac aattcaaaaa
     3601 tctgtgatgg ataatatgga tatatgggca tatgttgttg acaggaatac ctatgaatta
     3661 ctatttatca ataaaaaaat gcttgagtca gcaccaaaca ctcatgtagg tgatttatgt
     3721 tataaagcga tatggaataa tcaagataaa ccttgtaaaa aatgccctat gatatattta
     3781 aaagatggtg atgatactta taaatcattc atgcataata aaaagtttga ggtacaggca
     3841 aatataacta caactacttt gaaatggttt gatggtaaag atgcatgttt aatatttgga
     3901 agtgaaataa ctagtattga agctgaagaa aatacttaaa atactgtgtt atatatatac
     3961 ttaaaatcgc aatttgaatt tattagactt aaaatgtcta tataaatcat ttaagttgtg
     4021 gttttaagta ttttttatga tataattaag cgttaagaac aaaattaaaa gatacttttg
     4081 tataaaaaaa tatttgttaa atatatattg agcaggtgat aatatggaaa ataagttttt
     4141 accaataagc aaacaagata tgatagatag aggatgggaa gaattagatt ttgttctagt
     4201 tacaggagat gcttatgtgg accatcatag ttttggaaca gcaataatat ctagagtttt
     4261 agaaagtgct gggtataaag ttggaataat agctcaacca gactggagaa ctacagatga
     4321 ttttatgaag ctaggaaaac ctagacttgc atttctagtt aatgcaggaa atatggattc
     4381 aatggtcaat cattattctg taagtaaaaa gcatagagaa aaggatatgt attctccagg
     4441 tgggaaaatg ggttatagac cagatagagc tactatagta tattgcaata aaataagaga
     4501 agcatacagt gatgttgcaa tagtaatagg tggaattgaa gcgagcttaa gaagatttgc
     4561 acactatgat tattggagtg ataaggttag aaagtctatg ttaatagata gtggagcaga
     4621 tttattagtt tatggtatga gtgaaaagca gattgtagaa gtagccaatg cacttaatga
     4681 tggatatgac ccaaaataca ttagacatat tgatgggaca tgctatattt cagatacatt
     4741 ggaagaaata tatgataaat atatattaat tccatcatat aaagaaattt gtgaagataa
     4801 aatgaagtat gtagaagctt ttaaaattca atatgatgag caagacccat ttagaggtaa
     4861 tataattgtt caacctcatg gaagtaagta tctggttcaa aataagccag aaaaaccact
     4921 tagtagagaa gaactagatg aagtatatgg attaccatat cagaagacat accatcctgt
     4981 gtatgaaaaa tttggaggaa taccagctat agaagaagta aaatttagta tagtaagttc
     5041 aagaggctgt tttggtagtt gttcattttg tgcaataaca tttcatcaag gtagagcagt
     5101 gcaaagtaga agtgaaaaat caattattga tgaagcaata ggaataacaa atttagatga
     5161 ttttaaaggg tatatacatg atgttggagg tccaacagct aattttagaa gaccagcatg
     5221 taaaaaacaa attactaaag gtgcttgtaa aaatagacaa tgcttatctc catcaccatg
     5281 taaaaattta gatgcagacc acagtgaata cttacattta cttagagctg taagaaaatt
     5341 acctaaaata aaaaaggtgt ttgtgcgttc tggaattaga tacgattatg taatggcaga
     5401 taagaacaat aaatttctta gagagttgat agagcatcat gtaagtggtc agttaaaggt
     5461 agccccagaa catatatcag aagaagtttt aaagtatatg caaaaaccag caggaaaaac
     5521 ttatgataaa tttagacaga agttttttgc tataaatgaa gaattaggta aaaagcaata
     5581 tttgataccc tatttaatgt ctagtcaccc tggttctacc ttaaatagcg ctatagagtt
     5641 agcagagtat ttaagagata ctcactacca accagagcag gttcaggatt tttatccaac
     5701 tccagggact ctatctacaa ccatgtttta tacaggtatt gacccgctta caatgaagcc
     5761 agtttatgtt cctaaatcaa aacgtgacaa ggcgatgcaa agggctttat tacaatatag
     5821 agcacctaga aattatgatt tggtatactc tgcgttagtt gaagcaggaa gagaagactt
     5881 aattggtttt ggacatagat gtcttataaa gccaaaaaat gaaaagcctt attttaatag
     5941 aaataattct aaaaaaaatg tatctaaagg aacaaataaa aacaaaaaaa ctaatacaaa
     6001 taacagaagt aataaaaatc aacaaaaaag ttcaactaaa aaaaagaaaa aacattaaag
     6061 tataaataaa aatacttaaa aaagaaggat tattcgataa attaacagaa attagtataa
     6121 ataaatataa ttattttaat gacgttacct ttgggaggaa gagatgaaaa agtatatttc
     6181 tataatatta ttagtggtgt tgactatggt tgttttggta ggatgttcac caggaaaaga
     6241 taaccctaaa aataaggagc tatcagttgt caaacaagta aaagtagctg ttccagatgg
     6301 actaccagca gtggcaatag ctaaacttgc aaatgaaaat ccagagatta aagaaggata
     6361 tgaaacagtg tatagcattg aaaagacacc tgaagcgatt tccactagag tgatgaaaaa
     6421 agatgcagat atagctatag ttccttcaaa catggctgca atagcgtata ataaaacttc
     6481 atcatataat attgttggaa ctgtaggaat gggttcactt tatttggtgt caacagaaaa
     6541 tataaaagat tattctgatt tagttggtaa agaagttgga tgtactggaa aaggacttac
     6601 tccagacata actataaaaa gtcttttgtt acaaaaggat ataaattatt cagatataaa
     6661 atttaattat gtaaattcag caagtgaact ggtaccatta ttggctactg gtaaagttaa
     6721 aacaggtatt gttccagaac ctgcacttag tgctttgatg tctaaaaatc cagacataaa
     6781 aattataaaa agtttaaatg actcatggaa ggaagtaagt ggttcaaaag atggttatcc
     6841 tcaatctact ttaattgtaa agtctgaatt tttaagagat aataaagatt ttgttgattc
     6901 ttttgtaggt caattatcaa atagtataga ttgggcaaac aaaaatcctg aagaattagg
     6961 tgcatattct gaaaaaataa aaatatctac tgaatcaaag ataataggaa aatctcttga
     7021 aagagctaat ttaaaatata ttccagttaa ggacatgatt aaagattata aaaattacta
     7081 tgagaaatta gctaattttg atgataagac attaggaggc aaagtaccag atgaagcaat
     7141 atactttgtt gagaaataaa aaaaataaag aacaatttat agataaaatg gaggtaacac
     7201 tttcttgtgt tatcctctta tttttatggc aaattattgc tttaaaaatt gataatgata
     7261 tttttttacc aacagtaggt caagtattta atagtataaa agagattatg ctaaattcta
     7321 gtttctatat agatatactt tactctatgg ggagatgttt ttttagtttt ttactggcta
     7381 tgatttttgc tattatactt tcaatagtgt cttatttaaa tagatttttt agaaacttat
     7441 taaagccaat caatgctttg acacgttcaa taccaactat gatattggta gtacttgcac
     7501 ttatttggtt tgaaaaggat agtacccctt ttatagttgg atttactata gtttttccta
     7561 tattgtatga taacgttttg ggcgctatat tgaatataga caagaactta ttagaaatgg
     7621 ctaatgtgta taaaataagg tttatagata aggtgttaaa aatttattta ccagccataa
     7681 aatttcaaat tatatctata ctagtatcaa cattctcttt aagtttgaaa gttgctatag
     7741 caggagaggt atatagtcaa cctacatatg gtattggaac tatgatacag actgaaaaaa
     7801 ttaactttaa cacatctgga atatttgcat ggataattat tgttctttta atatctgcta
     7861 ttttacaaat agctcaaaag tttttagcaa ggagagcttt tttatggaaa agataaagtt
     7921 gagtattgaa aatataaata aaagatatga tagtcgtatt atatttagag attttaatat
     7981 tgatttttat gtaaatgagg taaattgtat ccttggaaaa tctggttgtg gaaaaactac
     8041 actcttgaac ataataagtg ggattattaa aaatgacacc aacaatctaa atatcaaaga
     8101 aaatttaaat agagtaggaa ataagcttga agctagttac atatttcaag atgatagact
     8161 tatagactgg ttaacagtag aagaaaatat aaagatagtt gtaaataaat actataataa
     8221 aactcaatta aataaaattt gtgatgaata cttggaattg gttggaatta gtgattataa
     8281 aaaattctat cctcagatgc ttagtggagg tattagacaa agagtaaata ttgctagagc
     8341 ttttatatat ccatcaaaaa atattataat ggatgaacct tttaaatcta ttgatgcaaa
     8401 gaatacacag cttataatgg ataatttcag aaatatatta agaaaagaaa aaagaactgt
     8461 gttatttgta actcataata ttgaggaagc attgttttta gcagatagga tatttatttt
     8521 aggagactct ccaattagaa taaaaaaaat attaaaaaat tctaaggaat tggaaaaaaa
     8581 tgaagttttg aagttgatat agagttataa taatactgtc gttttaaaat atatttggtt
     8641 aaaatctata agactatatt aaaatagtac agaatattca aaactgtgta taatgttcgt
     8701 attttataaa aaggaagtga atgtatggtt aagactaatg ctatgagaat attagattca
     8761 aataagattg attataaagt aatgtcttat gaagtgaaaa gtgaacatgt ggatggtgtt
     8821 gaggtggcac atgatatagg aagagatgta aatgaagtgt ataagacatt agtaactcaa
     8881 ggagttagta agaatatata tgtatatgta ataccagtac atgaaaactt agacttaaaa
     8941 aaggctgcaa aagtagctaa agagaaaagt gtagagatga ttcatgtaaa agatataaat
     9001 aagcttacag gttatattag aggcggatgt tctcctatag gtatgaaaaa gctttataaa
     9061 acttttgtaa atgaaagtgc aaagaattta gatacaatta ttgtgagtgc aggaaaaata
     9121 ggatatcaaa tagaactatc tccatttgat ttacaaagac ttataaaagt agaatttgta
     9181 gatgtaataa aaaaataaga attacatata aaatatagag cttatattct taataatagg
     9241 tgttgtagta ttaataaaat gaataataat tttaaaataa atattcagtt acttatgtgt
     9301 aattggtata aaaatattga gaaattttaa aaacaatggt aaagtgtaag tataatcacg
     9361 aatatttttt ataaagtaat ggagggatgt tcgcttgaga aaaataaaat ctgaacaaat
     9421 cgtcgagcag gtaaaaaaac tttgtataga agcgagccta tatttaggag aagatgtttt
     9481 aagctgtata aaagaaaaag cgaaaagtga aaagagtgaa gttggaaaaa atatattgaa
     9541 tatattagtt gaaaatgctg aaatagctaa agaaaaaaat ataccaatat gccaagatac
     9601 tggtatggct gtattttttg ttgaaatagg acaagaagtt ttaattgaag gagacacact
     9661 tactgatgct ataaatgagg gagtaagaca agggtatgaa gaaggctact taagaaaatc
     9721 tgttgtaagt ccaattaaca gagtaaatac aaaagataat acacctgctg ttattcatta
     9781 tgatatggta aaaggtgata aaattaaaat agaatttgca gctaagggat ttggaagcga
     9841 aaatatgagt aagatgaaaa tgttaaagcc atcagatgga ttggaaggaa ttaaaaaatt
     9901 cataatagat acagtttcag aagctggacc taacccatgc cctcctatgg taattggagt
     9961 tggtataggt gggactgtgg acaaatgtgc tcaaatagct aaaaaggcac tttttagaga
    10021 actaggtgaa tttaataagg acgaaaatat agcaaaactt gaaagtgaac tattaacagc
    10081 tattaataaa cttggtatag gacctcaagg cttaggtggt actacaacag ctttgggatt
    10141 aaacatagag acttttccta cacacatagc aggtttacct gttgttgtaa atataaactg
    10201 ccatgcatca agacataaga aggtagtaat ttaggaggaa aataaaatga taaaaataac
    10261 tacacctgta aatgaaattg atatagcaaa attaaattgt ggagatacaa ttagtttgag
    10321 tggtatactt tatacagcaa gagatgctgc tcataaaaga ttgatagatt gtataaataa
    10381 aggtgaagaa ttaccatttg acgtatatgg tcaaggaata tattatgtag gacctactcc
    10441 tacaaagcca ggagaagtta taggtgctgc aggtccaacg acgagttata gaatggatga
    10501 tttgactata cctcttttag aaagaggtct tagattgatg ataggcaagg gaaaaagaag
    10561 tgatgaagtt atagaaggta tgcaaaaata cggagcagtt tatcttgctg caataggagg
    10621 agctggagca tatatttcaa attcaataaa atcatgtgaa attattgcat atgaagattt
    10681 aggagctgaa gctataagaa agattgtagt agaagacctt aagcttacag tagcaataga
    10741 tagctatgga aataatatat atgagcaagg tcgagcaatt tatgaatgta aataatgttt
    10801 agaaataaat atgaatatca aaattaaaaa tagttgtgta tattttaagg aggaaaattg
    10861 atgtctaagg attatgcaaa attggcatta gaaatgcatg aaatcaacaa agggaaagta
    10921 agtgtagaaa gcaaggtaga agttaaaact aaggatgatt tatcaacagc atatacacca
    10981 ggggttgctg aaccttgttt aaaaatacat gaaaatcaag atgatgttta tagatacact
    11041 tctaaaggga atctagtagc agtagttagt gatggaagtg ctgtacttgg attaggtaac
    11101 attggtgctg aagcatctat acctgttatg gaaggtaaag ctatattatt taaacaattt
    11161 gcagatgtag acgcttttcc aatatgttta aagactaatg atgtagatga gatagttaaa
    11221 tctgtagagt tgatggagcc tgtatttgga ggtataaatt tggaagacat atcttctcca
    11281 agatgttttg agatagaaga gagattaaaa aaatctttaa gtatacctgt ttttcatgat
    11341 gaccaacatg ggacagcaat aatagttgcg gcagccataa taaactcaat aaagttaatt
    11401 gaaaataaaa aaatagaaga tttagaaata gttataaacg gagcaggagc tgctggtata
    11461 gccatagcaa agatactact taatatgaat gttaaaaata taatcttatg tgatagaagt
    11521 ggagcattgg aagctagtat agaaaatcta aactatgttc aaaaagaaat gttaaaagta
    11581 acaaatataa gaaatgaaaa aggaccttta aaagatatta taaaaggaaa agatgtattt
    11641 attggtgttt caggtccagg agctgttaca aaggaaatgg ttgaaagtat gtctgagaag
    11701 ccaataatat tggcaatggc aaatcctact ccagagataa tgccagaaga agcaaaatta
    11761 ggtggagcat ttataatggg aacaggtcgt tcagacttcc ctaatcaagt caataatgta
    11821 ctggcttttc ctggaatatt tagaggtgca cttgatgtta aggctaaaga gataaatgaa
    11881 gaaatgaaga tagctgctgc atatgcaatt gctaatacaa taagtgatga agaaatatgc
    11941 ccagagtata tattaccaga tgtatttaat aagaatgtag taaaaaatgt tgctaaggca
    12001 gttaaagaag cagcgataaa aaccaaagta aatagaatat aaatttttat atgttcatat
    12061 atccttatat tatcgggtat atgggcattt ttattatagg tttatactca tatatcctta
    12121 cttttatata catatcttta tgattaaagg tgttagaaaa tgtagtaaat tttatactat
    12181 cagactctat ctttattact ttagtagata catggttgta aaggtttata gaaaaaaata
    12241 taggaaggca gatttttatt gttgcgtata tatgagaatg atataatatg aatattataa
    12301 attaataaat ttaaatttat ggaggtacaa gagatgatgg aatataaagt taatgaccaa
    12361 gaacttaatg cttcaatgtt tatcccattc gtcaacagga tatggccagg agattatgat
    12421 atggataaaa cacagactgc attatcaaaa actttgaata taactgctta tgatgataaa
    12481 gtgcttgtag gatgtctgcg agttctttca gatggttatt attttggaac aattacagaa
    12541 ttgcttgttc ttccagagta tcagaaacaa ggcattggta gtaagctttt ccagcttgct
    12601 aaagagaaca ccccaactat gctatatttt ggtgcacagc caggagtaga agagttctat
    12661 gaaaaaaatg ggtgccaaag aagtctgcaa tcctacataa taaaaaagaa agatagttat
    12721 taaagttcca gctttcaata atcttaaaag tacaatattt tagtggaagc atttcatttt
    12781 ttattactaa tatgacataa acatgtcata ttagcattga tatactttta atatggttaa
    12841 gagccaaaga aaaatataag gagtgattta aaatggaaga aactaaattt tgccaatgct
    12901 gtgcaatgcc aatgggacaa actgatgaat tatatgggac aaataaagat ggaagtaaaa
    12961 gtactgatta ttgtagttat tgttttaaag atggtgagtt tacagctgat ataagtatgg
    13021 aagagatgat agaagtttgt atccctcata tgcttcaaag taataaggat atgactgaag
    13081 atgaagcaag aacaatgatg aacaatttct ttccaacatt aaaacgctgg aaataatttt
    13141 atgcaaaatt agttatatgc aaaacatgaa atatggtgtt gagaataagg ggtggtgtgc
    13201 tttatagcat accacctgtt ttgttacttg gagttcagtt attttcctaa atattttaaa
    13261 tatactattt tagataagtt ccctcttcat cttgataaat taatcctttt ttcataagca
    13321 ctccaagagc tcgtttaaaa tttttcttac ttgaattaaa taatatagaa atatctttag
    13381 gatcagattt atcattaaat ctcatatatc catcagaacc ttctaaataa cttaaaatct
    13441 tattttctaa agtatcaagt tcatcctttc tatttcctct aggagaaaga ccaagttttc
    13501 catcttcata tatttttatg acatgtaaat tttcaagaac atcaccagtt tttagttcag
    13561 taaagtactc attatgaagt attacaccag catatttatt gtctacacat atcattgcag
    13621 aattattagt ttggaatcca tatacaactc cagttacaat atctcctaca ttgtaagtat
    13681 ggtctgttaa taaatatgaa tctatatctg tagtagcagc aattcttttg cttttgtcta
    13741 aatatatata aaataaatat ttttcgtctc taaatagtgg ataagtctta gctttaaaag
    13801 gaactaatat gtctttagga agtcccatat ctataaaagt accaatgtct gtattatcaa
    13861 ctacttttaa atgtgctaca tccccaacct tagctaaagg cggtattaaa gttgcagcag
    13921 ttctgtcatc agaatcttta aatatgaaag catttacttc atcacctatg tttatttcat
    13981 tttttccgat taatctatta tgaagaagta tatcgtcttt tgtgttatta gtttgtccat
    14041 ccaaaaaata tccaaattca gtttttcttt ttactgtaag tttattaaaa tcacctatgt
    14101 ttatcaaatt aaaatcatcc tctcatttta tatttataat ttagccataa tatacttatg
    14161 tagtagtttg tcacagtatc tatattagta ttagtgaaat ttacaataaa taatatagtt
    14221 atttatgtat ttttcaattc tctagcttct tatatagtat aaactccaat ttcttttttg
    14281 tctttaggtt ttattaaaat ttttacaaaa taagttaaaa agtattgaaa taaaatttct
    14341 tttaaagtat aattggtata taccaaaatt ggtatatacc atatcgaaaa gtggtgacta
    14401 tatgaaaata gtaaataaat ctagtaatat accattgcat actcaattaa gttcaataat
    14461 aagagagatg atagaaactg gtgagcttaa agagggtgat gcaataatgc cagaaagaga
    14521 actttgcaac atacaaaatg taagtcgtat gacagtaaat aaaaccattg ttggattagt
    14581 tacagaagga cttctttata gggtacaagg taaagggaca ttcgttgcaa agcaaaaaaa
    14641 gaagtatcag ttttcaaatg taaaaggttt tactgatgtt atgaaagaaa agggagtaaa
    14701 cataaaaacg gatatattat cctttgagat ggaactacca gatgatttag ttaaaagaaa
    14761 gcttggaata agtgataata ctacaaatat atataagatt gtcagactta gatatactga
    14821 tggagagcca tttggattag aaatagtata tctatcagaa gaaatgtgta agggtctaac
    14881 aaaagggata ttggataatt cttcattata tagggtttta aatgaaaaat atggctataa
    14941 gatacaaaaa gctgaacagg taatggagcc agtaatactt tcagatgaag aaagtaagct
    15001 tcttgaaaca gatgaaggtg ctttagctct taaacttcat agaaattcct ataatagaga
    15061 aggtagccct atagaatata ccatatcaat atttagaaca gataaatatc aatatgaaat
    15121 agtattgagt gagtaggtga ataatatgaa atgtttaatt aatggaaaga taatattaaa
    15181 aaatcaaatc ttagaaaata aagtattagt atttgatgaa aaaataattg atatagctga
    15241 tagtgtacca aaagattgtg aagttataga tgctgatgga aaatatatat ctccagggct
    15301 tattgatatt catatacatg gaaacatggg aaaagataca atggattcga ctgatgaatc
    15361 tattgaaaca atttcaaagt caattatgag acatggagta acatcttttc ttccaactac
    15421 aatgactatg gataaagaac atgtttatga tgcacttgaa gttattaaaa aagcccaaaa
    15481 tagaaagctt gaaggggcac aagtattagg agcacattta gaaggacctt ttataaatga
    15541 gaattataag ggagcacaaa atgaaaaatt tataataaat tcaaaatacg aatttataaa
    15601 agaatataaa gatgttataa aagttataac ttatgctcca gaaaaagata ttgattttga
    15661 ttttactaga gaaataaaaa gatgtacaga tatagtttta tctattggtc atagtaatgc
    15721 aaattatgac caagctaaag aagctataaa tttaggagta actaatgtaa ctcacatgtt
    15781 caatgcaatg actggtttaa accatagaga cccaggcgtt gttggtgcag cacttacaac
    15841 taatgtgtac agtgagttaa tagcagatac aatccatata aataaagatt tatttcaatt
    15901 tatactaaat aataaaggaa aagaaagact gattttaata acagattcta tagaagctgg
    15961 tggtcttgaa gatggcaatt attctcttgg aggtcagaaa gtcatagtta agggtaatga
    16021 agctagactt gaaaatggag cattagctgg aagtgtgttg tctttaaata aaatggtatt
    16081 taacttctta gataatacaa accttaaagt gaatgaagca attaatttag cttctttaaa
    16141 tccagcaaca tctttgggaa taaatgacaa aaaaggaagc ttagaaatag gtaaggatgc
    16201 agatatagct gtatttgatg agaatttaga ttgtaaaatg acactttgct tgggggacgt
    16261 agtatataaa aatatatagt atacaaaaca aaccttaaag acagtaaaaa caatataaaa
    16321 aataataaat taaacttaca ttagtaaaag tagtagttaa aatttaggag gaataagatg
    16381 agagtattag tgtgtaaaga ttatgatgga atgagtaaaa aagccgctga aatgatagca
    16441 gctcaaatag ttttaaaacc aaattcaata ctgggactag ctacaggaag tacaccagta
    16501 ggtatgtata gagatttagt aaaaaaatac aatgataata tagtagattt ttcagatgtg
    16561 atgagcttta atttagatga atattataag ttaccaatat ctaatgacca aagctatgat
    16621 tattttatga aagagaatct atttaatcat gtaaacataa agccagaaaa tactcatcta
    16681 ccaaatggaa tggctgatga tattgaaaaa gagtgtatga actatgaagc ttctatagat
    16741 gcagctggtg gtatagatgt acaagtactt ggaataggtc gtaatgctca tataggtttt
    16801 aatgaacctg atactaaatt tgcaaagaga actcatgtag ttgaacttac agagtctaca
    16861 atagaagcta atgcaagatt ctttaaatca agagaagatg ttcctaaaaa agctgtaagt
    16921 atgggaatag gttcaatatt gaagtctaag aaaatattgc ttttagcttc aggagaagaa
    16981 aaagctgatg cagtatataa tactgtttat ggagatataa ctccagaagt tcctggttct
    17041 atacttcaac ttcataaaga cactatagtt atagtagatg aagcagcagc aagtaaattg
    17101 aatccaaaag attataaatt agtataagaa tagaatgtag tttaagtaaa aaatagctat
    17161 cattgagtaa tcaaatttat ttaatgatag ctatttttat ttaaattttt tacttctttt
    17221 tatttaaatt agttattatt gtttaaatta cttgcttatt actttttacg aaaactcgtt
    17281 atcaagaagt atccaaataa gatgttaaaa attattatgt ttagtgggat tctatcaagc
    17341 ataataaaat tacctataat tgggatatta ccaactggaa acataaagaa gaatacaggc
    17401 atcagtgata gtaaaaaaga tggaaaacaa agaagaagta atcttggaat atcaatatac
    17461 caactaccat cctttttgta ttctctaatc aataattcag ttcctagtaa taaaccaata
    17521 ccaccagagg aaattaaatt aataaaaatg tatcttttaa agtcttgcat ataaccagtg
    17581 taaaattgag tatagaaatc ataatttaat ttaacggcta aaaaatacat aagcaataga
    17641 atgattaaaa ataaaagata tctaagagct tttttcattt taaattctcc cttcagaaat
    17701 actttattta gttttatttt gttggaatct gattttatca tttagtttaa gaaatccata
    17761 atattagtga agaatgaaat aagtattata tatgaataaa tatttttaga attaaggtga
    17821 attgtagtgc ttaatataac tataatatta attgtttgaa tattcaataa aaagtttgaa
    17881 aaatatcaat tctgatataa actgaataaa tacagttgaa tattaaatta ttattttatc
    17941 aaaaatatgc aaagtactac accttcaaat atcacctaaa gtaattaaaa ggcaattaag
    18001 gtgaagtagt tcaagtattt ctaaaataag tttaataaat tctataataa tttatttttt
    18061 gccttaaaat tgccttaaaa tccaaacaat tttaaaacta atgtactata aaaagctggt
    18121 ataatttaaa tatagtaaaa aataagattt atcttatcta ttgggattta attatttaat
    18181 caatatattt ataccattta atttaaataa aaagtctatt aaggagtgag cttatgagta
    18241 agttaattta tatagcagat gatgaagata atataagaaa tttggtaaag acattcttaa
    18301 aaaatgaagg tcatgatgtt atggatttta aaacgggtga tgaactttta gaacaattta
    18361 atataaagga gtgtgactta gtaatactag atataatgat gcctggctca agtggttttg
    18421 aagtatgtac aaaacttcgt gagaaaagta cagtcccaat aatcatgctt actgcaagag
    18481 atacagatat agattatatt acagggataa ccttaggtag tgatgattat tttacaaaac
    18541 catttagccc aatgtctttg gttatgagag taaaatctat atttagaagg atagagtttg
    18601 aaaagaaaca aaattatgat aaatatagta actcgataga tatggaatta aaatttggtg
    18661 atgtaataat aaataaaaag aataaaatcg ttacaagtaa aaatgtaaat atagacctta
    18721 caccaaatga atataaccta ttgacttatt tgtttgaaaa tatagataga gcagtttcca
    18781 gagatgaatt attaaacaaa atatggggat acgatataga agttgagaca agggctgctg
    18841 atgatacagt gaagagatta cgtaaaaaaa ttttaaatac aaatatttta atagaaactg
    18901 tatgggggtt tggatttagg ttgaaggaga aaagttaaga tgaagaatgg aaatgacaag
    18961 aatagaattg gaaagattaa atccaaattt aaattaaagt tctcaaagaa aaatataagc
    19021 ataaaaacta ggattttgtt gagtatactt tgtttgataa ttatagtatt tatgataata
    19081 ttagtatctt ttaatgtatt tcttgataca tatataaaaa caactgcgaa tgaagaattg
    19141 acaaagtcta cagaaatagt agaacatatg gatagtaatt ttagacctat taagccacca
    19201 caagatgatg gaaagcttcc tcccaaagta ttatctaatt ttatgagaaa tgtacaagat
    19261 aaagttagga tggcagaaac acaatcagat gctgatgcta tggtagttga ttctaagtat
    19321 aacctgatat ttccaacaag agaggatgat ttcttaaaaa atgttgatga gatggagctg
    19381 attagggagt gtattcaaaa tgaaaaatta gatttaaatt cagatgaaaa tacacggata
    19441 tctaccagaa ataaggatta ttatatttca actgtaaaaa ttactagtat atatggtgaa
    19501 caagacaagt atcttatact ttttatagac atatcaaaaa ctctaaatct agcacaaaag
    19561 ataaatattg tattaatatc tgtaatgtgt tttgctggaa tattagcaat atttacagct
    19621 gtgattttat ctgagaaaat tgctaaaccg ataaaagagt tgtgtgagtt tgcaaaaaaa
    19681 atgggtcaag gagatttcaa aagaacctac tttgactttt cagataaaga attagtagag
    19741 ctctcaactg ttatgaataa gagtgctgag tatctggata agtatgataa tgaacaaaaa
    19801 atattttttc aaaatgcatc tcatgaatta aggacaccac ttatgtctat taaaggttat
    19861 gcagaagcta taaaatataa tgttatagat agtaaacatg caagtgatat aattcttgaa
    19921 gaaagtgata ggttaagtga tatggttgaa gatttattat acatttctaa aatagataat
    19981 ataactaaag attttgaact tgtagaatgt gatttaagag aagtactttc aaattgtgga
    20041 gctaggcaaa atgtaagagc tataaataag gggataaaat ttatttatga atttgatgaa
    20101 gaaatggttt tatttgaatg tgatgaaaaa aacatttcca aagcatttat gaatcttata
    20161 gaaaatgctt tgagatacgc taagagtgaa ataaaaatag tgtgtaagta taatcaaaaa
    20221 aatatagttg tgataataga agatgatgga attggaatca agaaagaaga tttacctcat
    20281 gtttttgaaa gattctataa gggagtagga ggaaatcatg gaattggatt atcaatagtt
    20341 aaatctattg taaataagca tggtgggcgt atatacgtag aaaatggcaa aaaaggagct
    20401 aaatttacta tattatttaa attgtaaaaa aattagagaa aatatagaga tgtttgaagt
    20461 tgttttttat atatatctgt tgtatactgt tgaaaaaaga acaatattaa gctgacatat
    20521 attacgatag ttgacattta aagtaaatgc ttaaatatag atacgaaagg aaaagtaaaa
    20581 tctgaagtgt atttaggttt aagtaagctt cttattttat aaaaaatatg tatgaaagaa
    20641 cagctgattt ttaatattac aaatttagta acggttgtat ttgaagcttt tgtcatccat
    20701 atgtttttat cagacttttt aggtcagaaa gaagggtata taaaagttgt aagatatgct
    20761 aaactgggtt ttataatatg tttaggattc tgtaatttaa taactttaaa ccctaaaatc
    20821 acaatgcctt taattttcat ccttattttt tcaacatcat ttttatataa aggaaattta
    20881 aagacacgat tgtttactac tgttttatta agtatattct ttatactgtc agaaattgta
    20941 gttacaagta tttttgtttt atttgtaaaa gaaggctttg aaataatgct tgaaaataat
    21001 agtataagag tattggcgac aattttatct aaaattgtct ttttgttgac ttgtaaaatt
    21061 atttgtctat ttaaaaagga tgtacattta gatatgccca taaagtattg gctcccttta
    21121 tttttaatac ctatatttag tttatttctg tctgtttcta tctttgatgt aagtaaattt
    21181 tttagtcttg aaagtttaaa atttctaagc ttaatatcta gtgttggtat tttatatatt
    21241 aattttattg tcttttattt atttaaattt attatagata aaactaaact atctatgaaa
    21301 tatgaactac ttgaaaaaga aataattcat aaggaagaat taagacttag taatgagtgt
    21361 tataaaatta ttgttgaaca gactgattct gtcgttttcg aatggaatat caaagaaaat
    21421 aaatcatttg tatcgcaggc ttggactgaa aaatttggat ataacaatgc atgtaagaat
    21481 atttttaaag aaattaaaga taaagactta gttcattctg aagataaagc tatatttgaa
    21541 ggttttcttg aaagtattaa aaaaaagaat atgcacaatc aagcagtata tcgtttaaaa
    21601 aaatctaatg gtgaatatat ttggtgtaga acatcaatta caagcattta taatgatgaa
    21661 aatgaacttt taagagttgt cggagtaatt gtagatgtag atagtgatat aaaaaaatat
    21721 gaagagttaa gaactagagc agaaagtgac tcattgacca atatatacaa taaaggtaca
    21781 tttgaaaaat tagtggaaga aactatagtt atgaatacag gtgataaaaa agatgcatta
    21841 ttcattattg atttggatga ttttaaagaa ataaatgata attttggtca tccatttggt
    21901 gattttgtac taaaaacatt tgctgataag atacaaacta gttttggtag taaagactta
    21961 gtcggaagaa ttggtggaga tgaatttgtt gtatatatgc aagattatgt tacagaagta
    22021 aatttgcata aaaaagctaa agaattaaat agagtacttt cggataatta cactgatttg
    22081 agttttagtt ttgatgcttc tgtcagtata ggtattgcaa ggtatcctca agatggaact
    22141 tcattttttg aattgtttaa aaatgcagat agagcacttt atagcataaa agcatcaggt
    22201 aaaaattcat attgtttatt tgaagaagaa ctatatgtac agtgaatttg aatttagatt
    22261 ttatgtgaga gtaagattta tatatacttg tggctgtctg atttataaaa tatgttactt
    22321 tgtatatttt tatatgtttc agtaaggtta attaacatga gcaaaggtgt aagtaaattt
    22381 atattagttt aagtttactt acacctttat aaaaatacaa ataatagatt catttacatt
    22441 cttaaatgat taaagctctt taccttctaa acatgcataa catatcgtta taattccagt
    22501 aaataagact aaaatgccca ttactaagat tacaatttca tcatctatta ctccaaatgt
    22561 ttttaaagta acttatttcg ctttgtatca taataatttg tctcttttta cattttaact
    22621 tctgctgaga tttgagttag atattcatta gaatctcgca cacttatatc atatagaaga
    22681 tattcttcat aaacaaaatc cccaatacgt aaattattct gattaaaaaa atttaataac
    22741 ttttcataag ccttgtaaat agtttcataa ctccctttat gataagcagt tacataaagt
    22801 ccctttggtt tgattgatac aggatatttc ttgtactctt tattaacttt tgtaaataaa
    22861 tatgaatatg attcaaagtc tttattaatt atatcttcac ctttaatgat tgagccaatc
    22921 gtaccataat cactcaattc atagttgtcc ataaagttaa tacattcata taaaaaattt
    22981 tcttcctcat ctcctaaaaa ctgttcttta tatgtaacag gtgttttgac caagtactct
    23041 tcttcatgtt cttttaaagt aatagtattc gcatctatat tacatgcact tttagtaaat
    23101 gaaatagtag attccattag agcttgaata ttatttagtt tttcaatttc atttttaata
    23161 tcaatggttt tcttttctaa aagctcaatt agtaaattag gtgttctttt gtctatataa
    23221 gctttaattt cttttaaagg catttttact tccctaagtg aagaaattat accaaaaatg
    23281 ctaagttgat ggtatgagta gtatctatat ccattttctt tctttaattc tggtgagaaa
    23341 agacctatat catcataatg gaaaagtgtt tttttattga ttccacaaat ctttgcaaat
    23401 tctccagttg taaaataatt ttttgaaact tgactcataa ttataattcc tccttgacta
    23461 tcctgttaca gtatagttta tcatagtatt ttgtaaagga gtgtgattat atgaaaaaat
    23521 taattcattt tttaaaacca tatagagttt taattgttgt agttttgata tttacgtttt
    23581 tacaaacact tggaactttg tatataccaa cacttacagc aaatatagta aataatggtg
    23641 tagtaaaggg agatatagat tatattgtaa aaacaggttt aatgatgatg atagtagctg
    23701 gtataacagc tttatcagct gtgttagttt gtaaagtatc agcaaatctt tcatctggat
    23761 tttgtagaga tattagagaa gcagtattta taaaatcaca agatttatca ataaatgatt
    23821 ttaataatat aggtacagca tcaatgatta ctaggagtac tagtgatatt actttaatag
    23881 gtcagtctgt gtttatgttt attcaattag tattaccagc accaattata actgtttctg
    23941 gtctattctt agcatattct atagataaag caatgacaat tattattgtt gtagtaatgt
    24001 ttttattcat gctttcagca tttttagttg gtaaaaagct tataaagttg tttaaaatga
    24061 tgcaaataaa gatggataat atgaataggg tgttacgtga ggtagtaact ggagtaagag
    24121 ttataagagc ttttaatagg agtcgttttg aaaaaaagag atttgataga actgcaatag
    24181 attattctga aacagcaatt tcaataaata aaatatttgc agtacttatg cctattgtaa
    24241 tgttaataat gaatttaggt atagtaagta ttatttggtt tggtgggatg agagtcagta
    24301 atggaaatat ggaaataggt catataatgg cacttgttga atattgtatc ttaattttat
    24361 tctatttaat catgggagta atggtattta tgtacatacc tagagcaggt gcatgtgcag
    24421 atagagtaaa tcagatatta gatatagaac ctgaaattgt agatggaaat ggtcataaag
    24481 atactgtctc agagagagga catttagtat ttaaaaatgt aaccttttca tatgcacaat
    24541 cagaagaacc tgtgttaaat aatataacat ttgaagcaaa atctggagaa gtaactgcaa
    24601 ttataggaag cactggctca ggcaaatcta ctattgcaaa tataatacca cgtttttttg
    24661 aaattcaatc tggagaaata tctataaatg gtcaggatat taagaagatt cctcaaaaag
    24721 aacttagaga taagattgga tttgtaccac aaaaagcttt tttatttagt ggaacaatag
    24781 aagaaaatat aaggtatgga aaagaagatg caagtattga agaagtaaag catgctgcaa
    24841 gtatagctca agctgatgaa tttatttatg atatggaaga caagtatgac tcatttgtag
    24901 cacaaggtgg aaataatttg tcaggtggtc aaaaacagag aatatccatt gcaagagcgt
    24961 tagttagaaa gcctgaagta tatgtctttg atgatagttt ttctgcatta gattttaaaa
    25021 cagataaaag acttagaaaa gcgttgaaaa atgaaatcaa agattcatca gctataatta
    25081 tagcacaacg tataagtaca atcatggatg ctaatcagat tatagtttta aatgatggaa
    25141 aaattgtagg tattggaaaa cataaagatt tacttgaaaa ttgtgaagtt tataagcaaa
    25201 ttgcggattc acaacttagt aaagaagaac ttgcataaaa tgaagaatta atctgatatt
    25261 tggaggtgta tgatatgagt gaaaaaagaa tagatgaaca agatatagaa gtacttagtt
    25321 ttgaagatgg catgtcagca gaaaaagcta aggatgcaaa aaaaactact aagagattat
    25381 taaaatatat ggcaaaacaa aagtttaaaa tattaattat ttttatttca gtattgataa
    25441 gttcagcgct tacagtttta gcacctatgg ttatgggaaa agctattgac caactattta
    25501 atggaataaa aactgcagtc caaacaggta caaaattcag tgtgaatttt agtactatgg
    25561 gagggatagt atcaatactt ctagggttgt acttaattag tgcagtattt atatatattc
    25621 aacagtatat tatgtcagga gttgcacaaa atctagttct tagcatgaga aaagatttaa
    25681 gtgataaact caataaactt cctcttaagt actatgattc tcataaaaag ggggaaacac
    25741 ttagtatagt aacaaatgat ttagaaaaag tagcagatag tttacaagaa ggattaatgc
    25801 aacttattac agcagtagtt acagtagttg gttctattgt aatgatgata agtataagtg
    25861 taccacttac aatagtatca gctataacat tacttgtttc attgggtatt actgttgtaa
    25921 ttgcaagaaa atcacaagaa agattctctg aaaatcaaaa ggcactagga gagttaaata
    25981 gcaatataga agagatattt actggtcaaa tagtggttaa agcatttagt aaagaaaagg
    26041 atactataag aaactttaaa atattaaatc aaaatcttta taatgcaagt agaaaagcac
    26101 agttttcgtc atatgcaata tctccaatta ttagatttat aaacctaatt ggctatgtta
    26161 ttatagcagt tgtaggtggg atatttgcat caactggagc aatgactctt ggtagtatac
    26221 aagcgtttat tcaatatgta aatcaagcat cagagcctac tacagaaata tcttatattg
    26281 taaatatgct tcaagcagca atagcatctg cagagagagt ttttacagtt atggacgagg
    26341 tggaagagat aaaggatgaa gaatcttcaa aggttattag catgcctaaa ggtaaagtac
    26401 aatttgagca tgttaaattt ggatatagtg atgattttat tcttatgaaa gatattaata
    26461 tcaatctaaa tgcaggagat aagattgcaa ttgttggacc tacaggagct ggaaagacaa
    26521 ctcttgtaaa tttacttatg agattttatg agatacaagg tggaagaatt actattgatg
    26581 gtgttaatat aaaagattta aagcgtggag aacttagaac tatgtttggt atggttcttc
    26641 aagatacatg gctatttaat ggaagtataa aagaaaatat tgcatatagt aagtcagatg
    26701 ccacaatgga tgaaattgta agagcagcaa aatcagcaag agtagaccat tttataagga
    26761 ctttaccaca agggtatgac actatattga ctgaggatgc ttctaatcta tctcaaggtc
    26821 aaaagcaact tctaacaatt gccagggcaa tactttcaga cccatcagta ttgattcttg
    26881 atgaagcaac atctagtgta gatactagaa cagaggtaga aattcaaaag gcaatgaata
    26941 acttgatgaa gggaagaact agttttgtta ttgcacatag attatcaact attcgagatg
    27001 ctgatttaat attagtaatg aaagaaggaa ctattattga acaaggaagc cataaggaac
    27061 ttattgaaaa gaaaggattc tatgaagaac tttataacag tcaatttaca agtgaatatg
    27121 atgaagatgt tgtatgatta tcaagtttta ggcaactaaa tgattgataa atattaagtt
    27181 aaatatagta acatgtaagg ttatatggaa taagagtatt tctctatttc atataacctt
    27241 ttttatttat caaaataaga taaaatttcc tttctaaatt agattgaaga atgtatttat
    27301 caatataaaa gtaaaataat cattattatt agtgaagtaa atattgtttg ccacatatat
    27361 gccataaaga tgcacttatt ttacggagat ttaacaaagt agtgtaaagt atactctaaa
    27421 tataaaataa atcaaataga gttaaataaa ttgagaggtg atataaatag tgaataaaaa
    27481 attgaactat agatttgaaa tgaagcacaa aataactgaa gcagatgtgt tagctttaaa
    27541 atcaagactc tatccaataa tgaagaaaga tgaaaatgca tctaaagatg gaaaatatct
    27601 tattaggagt ttatattttg atactcctga agataaagca cttttggata aattaaatgg
    27661 cgttgcaata agagaaaagt ttaggataag attttataat aatgactgct cttatataag
    27721 gttagagaaa aaaatcaaac attacaacat gacatcaaag ctatcaacta atttaaccaa
    27781 aaaagaagta ataaatatac taaataatga tattgaattt ctaaaagagt cgacaaattg
    27841 tttattaaga gaattttatt tgaaattaaa atgtgaaaga ttagaggcaa aaagcatagt
    27901 tgattacaat agagaagctt ttatttatcc agttggaaat gtaagagtta caatcgatag
    27961 tgatattaaa acttctgtaa attcggtaga tttatttaat aaagatttgc caactgtttc
    28021 ggtaattgat gagaatatga ctgtattgga ggttaaatat gatgaattta taccagattt
    28081 tataaaggat ttaattcaaa ttaataagac tacctctaca gcagtttcaa agtatgcttc
    28141 aagtagatta tatatttaag aataaaggct atgatttata taaagatata cataaataag
    28201 attaaaaaac aaataagtta aaaataaaaa ataaataagt taaaaatagg aaggatgatt
    28261 ttaattatga catttaatga tatttttaaa tcaagtttta tagaaaacgt atcaggtttt
    28321 tcatttgtgg acagtgcttt agcactaggt tcagcttttt tagtaggttt gtttatatat
    28381 atggtctata aaaagactta tatgggaatt atgtattctc gaccattcaa tgtgtcgctt
    28441 gtagcactta caatgcttac aacttttgta atattggcag ttacttcaaa tgtagtttta
    28501 tccttaggta tggttggtgc tttatctata gtaagattta gaacagcaat taaagaccca
    28561 atggatttag tatttctatt ttggtcattg ggttcaggta tagttttagg agcaggtttg
    28621 attcccttag ctgtcatggg ttcaataatt atgggattga ttctaatatt cttttcaaat
    28681 aaaacaatat ctgaaactcc atatatattg atggtaaatt gtaataatga agattcagaa
    28741 gatatagcaa ctgataaaat taaaaaagta tttactaaat atcaaataaa atcaaaaagt
    28801 gttacaccag aaaaaggaat agaattagtg tttgaagtaa gaatgaaaga tggagaaaca
    28861 agtcttataa atgacttgag tcaagtagat ggagttacta atgcagttct tgtaagttat
    28921 aatggtgact atgtagcata gagaggagta atcttttatg aaagataaaa aatttaccct
    28981 tcttatctcg attatgatta tatttttatg tgctgtagtt ggagtttata gtacatctag
    29041 caacaaaagt gttgatttat atagtgatgt atatattgaa aaatatttta acagagacaa
    29101 ggttatggaa gttaatatag agatagatga aagtgacttg aaggatatga atgaaaatgc
    29161 tataaaagaa gaatttaagg ttgcaaaagt aactgtagat ggagatacat atggaaacgt
    29221 aggtataaga actaaaggaa attcaagcct tatatctgta gcaaatagtg atagtgatag
    29281 atacagctat aagattaatt ttgataagta taatactagt caaagtatgg aagggcttac
    29341 tcaattaaat cttaataact gttactctga cccatcttat atgagagagt ttttaacata
    29401 tagtatttgc gaggaaatgg gattagcgac tccagaattt gcatatgcta aagtctctat
    29461 aaatggcgaa tatcatggtt tgtatttggc agtagaagga ttaaaagagt cttatcttga
    29521 aaataatttt ggtaatgtaa ctggagactt atataagtca gatgaaggaa gctcgttgca
    29581 atataaagga gatgacccag aaagttactc aaacttaatc gttgaaagtg ataaaaagac
    29641 agctgattgg tctaaaatta caaaactatt aaaatctttg gatacaggtg aagatattga
    29701 aaaatatctt gatgtagatt ctgtccttaa aaatatagca ataaatacag ctttattaaa
    29761 ccttgatagc tatcaaggga gttttgccca taactattat ttatatgagc aagatggagt
    29821 attttctatg ttaccatggg attttaatat gtcatttggt ggatttagtg gttttggtgg
    29881 aggtagtcaa tctatagcaa ttgatgaacc tacgacaggt aatttagaag acagacctct
    29941 catatcctcg ttattaaaaa atgagacata caaaacaaaa taccataaat atctggaaga
    30001 gatagtaaca aaatacctag attcagacta tttagagaat atgacaacaa aattgcatga
    30061 catgatagca tcatatgtaa aagaagaccc aacagcattt tatacttatg aagaatttga
    30121 aaaaaatata acatcttcaa ttgaagattc tagtgataat aagggatttg gtaataaagg
    30181 gtttgacaac aataactcta ataacagtga ttctaataat aattctaata gtgaaaataa
    30241 gcactctgga aatcaaagtg atgaaaaaga agttaatgct gaattaacat caagcgtagt
    30301 caaagctaat acagataatg aaaataaaaa taaaactaca aatgatagtg aaagtaagaa
    30361 taatacagat aaagataaaa gtggaaatga taataatcaa aagctagaag gtcctatggg
    30421 taaaggaggt aagtcaatac caggggtttt ggaagttgca gaagatatga gtaaaactat
    30481 aaaatctcaa ttaagtggag aaacttcttc gacaaagcaa aactctggtg atgaaagttc
    30541 aagtggaatt aaaggtagtg aaaagtttga tgaggatatg agtggtatgc cagaaccacc
    30601 ggagggaatg gatggtaaaa tgccaccagg aatgggtaat atggataagg gagatatgaa
    30661 tggtaaaaat ggcaatatga atatggatag aaatcaagat aatccaagag aagctggagg
    30721 ttttggcaat agaggaggag gctctgtgag taaaacaaca acatacttca aattaatttt
    30781 aggtggagct tcaatgataa taatgtcgat tatgttagtt ggtgtatcaa gggtaaagag
    30841 aagaagattt ataaagtcaa aataagatta aaattgaata taaataattt taatactgtt
    30901 aagtctaaat atttacttag cagtattttt tagaaaataa tgtatttggt tactaatata
    30961 aggtaataaa ttgataaaaa ttaaatacag catattaata atacataata aagtaataaa
    31021 aaaactgttt aagtataata acttatattt agacagtttt tttcatttat aaataatata
    31081 aatgaaattg aaaacatttg aaggatagaa attggttgga taaatgtata aattacttca
    31141 ccaaaaaata atgacaaaaa ttgtaactaa gttgtaataa aatggtagtt atttagcata
    31201 aaataatgta tcatagaagt atattataaa attaataaaa taagattttt gtaagaaaac
    31261 tgctggcttt tgatatttag agtgagtagt taaattatgt ttaggagggg tagaatttgt
    31321 tgcaaaaagt attatggaaa tttttaaagc tagtagtcgg tttatttata tgttcagttg
    31381 gtatagtatt gacgataaat tgtaaccttg gattatctcc ctgggatgta tttcatcaag
    31441 gactttcaaa tcatatagga ataactatag gaactgcttc tataattgta ggctctatag
    31501 tagttattgc tgatgtcgtt cttggagaaa atgtaggatg gggaactgtt tttaacatgc
    31561 tactaattgg attttttatg gatttacttt tatatagtaa tttaattcca gaggctgata
    31621 atttatttgt aggaataatt atgttgatat taggattggt tcttttgtct gttggaatgg
    31681 tattttatat gggaagtggt ttaggaagtg gacctagaga tggtttgatg gttgcaattc
    31741 aaaagaaaac aggaaaatca cttaaattaa taagaggtac tatagaagtt ggagcattaa
    31801 tagtaggatt tttattaggt ggaaaagttg gtataggaac tataataagt gcatttggat
    31861 tggggtattt cacacaaatg gtatttggct tatttaaatt agattgtagt aagattaaac
    31921 atagatttat agtagatgat ataaaattta tcaaagtgta tatgagtggt gagaaaaaag
    31981 ctgctgttca aaatatagtt aagtaattta agaataaatt caacgaaatg ttaagtattt
    32041 taaattaaca ttttgtttag atagataaat tgaatattaa aagaatatta aaatatgagg
    32101 attgctagaa cactataaaa tatagatttc tagtaatttt ttatttgttc aatatttttt
    32161 tagtactaga agtcttattc tctatttaat gaatgaatta atttataatt agagatacta
    32221 aactttatag atattaatat aaacaccttt aaactgtgta ttttccaaag cctttaaaat
    32281 gcttgtattt attctaaata aaaaaataaa aaaatgtcaa aaaaactctt gtattatatc
    32341 caaattttat atataattac ctatgttgtt tagaaatttt aaactcaatg tttagtaaac
    32401 aaaatgttta gtaaaataaa acagaaacta ggaggtgcaa catggatata ggtgaaaaga
    32461 taaaaagatt aagaacagaa aaacaactga cccaggaaga gttagctaat agatgtgaat
    32521 tgtcaaaggg atttatttct caattagaaa ataacttaac atcaccatcc atagctaccc
    32581 ttatagatat acttgaaata ctaggtacaa atttaaggga attttttaat gaaatagatg
    32641 atgaaagaat cagttttaca aaagaagata tgtttgaaac tgaagatgaa gatttaaaat
    32701 ataaattaaa gtggttaatt ccaaattcac aaaaaaatga aatggagcca ataataataa
    32761 cattgtatcc aggaggacag tataaagaag aaaagccaca tgaaggtgaa gaatttggat
    32821 atgtattagc aggttcaata tatgtccata taggcgaaaa gaaaaataaa gtaaaaaaag
    32881 gagagagttt ttactttaga ccgaaagcaa atcactatat atcaaacgag ggcaaaacta
    32941 cagcaaaagt gatttgggta agtacgccac catcatttta gaatagaggt gtttaataat
    33001 tggtagaaaa tataatagaa ttaagggata tatctaaaca ttatgaagaa cttactgttt
    33061 tagataattt caatttagat ataaagaaaa atgagtttct aacattgctt ggaccaagtg
    33121 gatgtggaaa aactacaaca ttaaaaataa tagcaggatt tgagtatgct gatgatggta
    33181 aagttttatt tgaaggtaag gagataaata atttgccacc atatgaaaga caagtaaaca
    33241 cagtatttca aaaatatgct ttatttccac acatggatgt ttatgaaaat gtagcttttg
    33301 gattaaaaat taaaaagact ccaaaagatg taatagatgc taaagtaaaa gaggttttga
    33361 aacttgttgc actagaaggt tttgaaagac gacaagttga atcattgagt ggaggacaac
    33421 aacaaagaat tgcaatagca agagctctag tcaatgaacc aaaggtatta ttactagatg
    33481 aaccacttgg agcacttgat ttaaagttaa gacaagagat gcaaatagaa ttaaagagaa
    33541 tccaaaaaaa attaggaata acatttgttt ttgtaactca tgaccaagaa gaggctctta
    33601 ctatgtcaga tactattgtt gtaatgtata agggcaaaat tcaacaaatg ggaacaccac
    33661 aagatatata caatgaacct aaaaattcat ttgtagctaa gtttataggt gaaagtaaca
    33721 tatttgatgg aattatgata gaagattata aagttaattt ctgtaataga gattttgagt
    33781 gtgttgataa aggattcgaa aaaaacgaaa atatagaagt agtaataaga ccagaagata
    33841 taaaaatggt aaagccagaa gaaggaatgt taaaggggaa agttacatct acagtgttta
    33901 aaggagtgca ttacgagata gaattgaatg aaaatggaag attgtggata cttcataata
    33961 ctaaaaatgc tgaggttggg actgaactag gcatggatat atatccagaa gatatccata
    34021 taatgagaaa agagaataac taagatgaaa agaaaatctt ttttagcata tccatatgta
    34081 gtttggagtg cgatatttgt aataattcct ttaatattag tagtattttt tagttttaca
    34141 aaagaatcag gtggaggtta tgcctttaca cttgagaatt ataaagaagt aattgaccct
    34201 atatatatga aagtttttgg gcgttctatt cttttagcag gaggagctac attaatatgc
    34261 cttatagttg gttatccagt ggcatatata atttcaaagg ctcgtgtaag tagaagaggt
    34321 tcattaatat tattgtttat tcttcctatg tggatgaact ttcttttaag aacatatgca
    34381 tgggttgcta tattaggaaa aaatggactt ttaaatacat ttttaggttg gtttggaata
    34441 caaccattag caattttgta tactaatttt gctatacttt taggtatggt gtataacttt
    34501 ttaccattta tggttcttcc aatatataca gcactatcaa agatggataa tgatttgata
    34561 aacgctgctc atgacttggg tgcaaataat atgacagttt ttagaaaaat tatatttcct
    34621 ttgagtttgc caggtgtaat gtctggaata actatggtat ttatgccagc agtcactact
    34681 tttgcaatat caagactgtt aggtggaggt aaaataatgc tggttggaga tttgattgaa
    34741 caacagttta cagttgttgg agattggaac tttggttcag ctatatcgat atttatgatg
    34801 atagtaatat taatatctat gtctataatg tcaaaatttg gagatgaatc tgacaaagaa
    34861 ggcggtgggt tactatttta aaattaaaga aaataacttc taatatatat ttagcattag
    34921 tattcttatt tttgtatgca cccatatttg ctttggtact attttctttc aatgattcaa
    34981 aatcaatggc aagatggaat ggatttacat ggaagtggta tggtcaatta cttcaaaatg
    35041 agagtataat gagtgcttta tattatacta ttgtaatagc tatattagcg tctgtaatat
    35101 ctacaatagt aggaactata agtgctatag gaatacataa gatgagaggt aagagtaaga
    35161 aattaatact aaatgtaaac tatcttccta ttttaaatac agagatagtt acagcagtag
    35221 ctcttatgag tctgtttgta tttgtaaaaa tggaatttgg atttacaaca atgctattgg
    35281 cacatataat gttttgtttg ccatacgtta tactttcagt tttgccaaaa atgaagcaat
    35341 tacctgataa tatagaagat gcagctatgg acttgggagc aacacctata tacgctctta
    35401 gaaaagtaat tttaccacaa ataaaaccag gtatagtttc tggattttta attgcattta
    35461 ctatgtcaat agatgacttt ataataagtt tctttaatgc tggaaatggt gtaagcaatc
    35521 tttctataga aatctatgga atggctagaa gaggtataaa acctgaaata aatgcattat
    35581 caacaataat gtttgcagtg gttctaggtt tacttttact agctaataaa aaagaatcta
    35641 tagtaagggg gattaaataa tgattaagtt taaaaaagca atatccctta tagctgtagg
    35701 tatgatgaca gttactttat ttacaggatg taataaagca actgattcta caaaagtttt
    35761 aaatgtatat aatgttggag attatataga tgagtctctt atagataagt ttgaaaaaga
    35821 aacaggaata gatgttcaat attcaactta tgatactaat gaaatgatgt atcaaaaagt
    35881 aaagagtggt agtacacact atgatttagt atttccttca gactatatgg tagagaaaat
    35941 gaaaaatgaa ggtcttttgg aaaaattaga ttttaagaat atacctaata tgaaatattt
    36001 agataagagt tttttaaatc ctgtatacga caaaactaat gaatatagtg ttgcatatat
    36061 gtggggaact cttggaatat tgtacaataa gaaagaagtt aaagacccta tggatagctg
    36121 gaatatactt tggaatccaa agtataaggg aaatataatg atgtttgact ctgttagaga
    36181 tactataggg ataactctta aaaaattagg atatagcatg aatagtgtaa atccaaaaga
    36241 aataaatgaa gctaaaaatc ttttaatgaa acaaaaggat ttagtattgg cttatgtaaa
    36301 tgatgaaggt aaggatagat tgcttggtgg agaagtggca atgggtatgc tgtattctgg
    36361 agatgcagtt acactaatgg agcaaaatcc tgaccttgat tatgctatac ctaaagaggg
    36421 aactaataaa tgggtagatg ctatgtgtgt acctacaaca gcacaaaata agaaagaagc
    36481 tgagctgttt ataaactttt tattagaccc agagaatgca aaagtaaatg ctgagtacat
    36541 tgggtattca acacctaata caggagcact aaaattatta gacccagaaa taactcagaa
    36601 tcctgttgca tatccatcta aagaagtact tgataaatgt gaaacttttg aagatattgg
    36661 tgaaaatata aaattatatg acaaggcttg gatagagtta aaatcaaaat agggtcttgt
    36721 tgttttaagt aaatttactt aataaatact taataaaact gttctttttt agaaaattta
    36781 ttttctaatt attgaacagt tttatttttt gtttaagtta tattcatatg caatttaaat
    36841 agtttattaa taaatgaaaa cttatttgta taatgacttt aataataatt agaaaaaatg
    36901 ggcaacttaa tagaataatt ggaggtgtaa atttataaaa aatgaatagg ataaataaaa
    36961 aaatagattt attaatattg gctttgctcg tttttatatt tttaattgtt ggaatagtaa
    37021 tactatcgat taggacagaa aataaattga atgtgttcat aatgttagca ataatttttt
    37081 ttataataat gttaacttat ttatcaaatt cagtagtggg gttgataaca agttcaataa
    37141 ttatatttat gtatacatcc tatattttat ataacaatat tactcacaat atggatgttg
    37201 aatttatatc atatatgtgg ataatagcaa caccagtatc ttcaattata atgggtaatc
    37261 tgaacaaaag cataaatgaa ttgcaaaata caaataaaaa actatctgaa cagtataagg
    37321 aattagtgac tattgatagt gaaactggac ttagaaattt aaagattttt tataatgatg
    37381 taaatatgga gataagtaaa tctattagac ataatactga tttttctctt atgatagtaa
    37441 aattaccata ctacggaaac ctacagacta tatttggtga aaacaaaact aataaaatag
    37501 taaaatatat tggttcaaat attatagaat gtacaagaaa tgaagatata atttatagtt
    37561 tacaaaaaga tatgataggg atactaatgc caaatacatc tttggaaggt tcaaaagttg
    37621 ttaaagacag aataaagaaa aggataaaag aattaaattt agatttaaac aataggggaa
    37681 aatatgtaaa tatagatgtc aaaattgcat ttttacaata taagagtagt tttggagata
    37741 gtataaattt taagaatata gttgaagagg aacttcaata tgatgtttaa aatatttaat
    37801 aaaagtctat taaaattagt agttgtatta tcaatagtac tgacaatatc aaattttagc
    37861 ttatcttcat atgcatcaga aattacttcc agcacagata aggtattaat catatatgat
    37921 tctaagaaag aaacagctta taatagagat attttaaata ttatgaggac tctattggga
    37981 agatttagtt cagatataga gctattaaaa ttgagtaact atgatggtga gataaataaa
    38041 aattattaca gtcatatatt tattttagga atcaatgaaa actcatataa taatgataaa
    38101 aacactaaaa acttgattag ttccttaaat tcatataaag gaactatatg ttggttagga
    38161 tatggtatag aaaatctttt ggaacataaa aaatacaatt tagactatgt aggaaaaaca
    38221 aacaatatag ttagtgtaaa ttatagaggt aaatcatata acttggatga acattatgtt
    38281 tttaacattg tagaatcaaa agatacaagt aataaagtaa taggaagtat taatgatacc
    38341 ttaaataagt atccatatat aataaatgat aaaaatcttt tttatgtatc aaaattagat
    38401 ttagatggag ttttatttta tatattttgc gattcactta atgatatttt taatattaag
    38461 acgtttgata aaggacgtat atttgtaaga atagaagatg tacatgcttt tagagaacca
    38521 aaaaatcttg tagagatagc ggattattta agtagtaaga atataccatt tacgattgca
    38581 ttaataccag catatgtaaa tcctaaaaat cataaggtaa taactttatc agaaagccct
    38641 gaaattgtca aagcaataaa atatatgcaa gataaaggtg gaactgtgat attgcatgga
    38701 tatactcatc aatacaagaa agaagaagtt tctggagaag ggtatgaatt ttgggatggt
    38761 aaaaaagatg aacccttaaa agaaaatatg aagatatttg tcaaagatag agttttgaat
    38821 ggtcttagag tatgtataga gaatggaatt tatcctcttg catttgaagc gccacattat
    38881 gcaatggaat cagagggata taaagaatta aaaaaatatt tttctactta tatggggcaa
    38941 catcaaaata atgataaaaa atttagcaca aatacatatc cttatattat tagggataca
    39001 gaggagttta atatatttat acccgaaaat ttaggatata tagacccaga agataagttt
    39061 acttttcaaa atataaaaga aaatttaaat aaattatcca ttgtaagagg ttttagtgga
    39121 gggttcttct ttcattcata tttaaacata gagtatctaa aaaacacaat agaatattta
    39181 gaaaaacaga atatagaatt tatgaattta agagatttta ataattgggt aaaagttgat
    39241 gaaatacaaa taagaaataa tggagatgaa attatagtca actatgataa ggacttagat
    39301 gaaataacta aaagtgatac tagatttaaa tccatatcca atattagtaa agttttaata
    39361 ttcatagtat ctataagtgt tttaatattt gtgattatat ttatatattt taagagaata
    39421 gataaaaaga aatttttaaa ataaatgatt ttatattaga atcaatattt taaaatattt
    39481 taggagaaat ttatgagaga tttaaatgta tcagagtatt tgttcgtatt tagtctgttt
    39541 agtatatggt ctttattgct tataaatatt attttagcta tgggtggata tatattttat
    39601 tttaaaaact ttgataaaga aataaaagaa attgatgaat atcctatgat atcaatactt
    39661 gttcctgctc ataatgaagc taaagtgata ggtagaactg tggagtcttt gctattactc
    39721 aattatccta agagtaagat ggaacttatt gttataaatg acaattcttc tgataatagt
    39781 aaagaaattt tagaaaatat aaaggatagg tacaacaatt ataatttcac tataataaat
    39841 acagatagtt taacaggtgg aaaaggaaag tctaatgcat taaatattgg atatacgatt
    39901 tcaaaaggag attttatagc tgtttatgat gcagataaca caccagataa aaatgcactt
    39961 agatatctag tacaaactat agtaatgaat gatgaattag gtgctgttat tgggaaattt
    40021 aggactcgaa ataaaaataa aaacctatta accaaattta taaacataga aacattaagc
    40081 tttcaatgga tgtcacaagc tggtagatgg caacttttta atctatgtac aataccagga
    40141 actaacttta tattgaggag aagtatcata gaagaaattg gaggatggga tagtaaagca
    40201 attgcagaag atacagaaat aagttttagg atatataaat tgggatacaa gataaagctt
    40261 gtaccacaat ctataacatg ggaacaagag ccagaaactg ttaaggtgtg gataaagcaa
    40321 cgtactagat gggcaaaagg gaatatatat gtattaatga aatatataaa aaatatattt
    40381 aaacagggaa gaaataagat tgtgtttgat atagcttact ttttttctgt atattttcta
    40441 tttttaacat ctgtaattat atccgatatt ttatttgttt taagtatatc taaactagta
    40501 gaaatttcta ttccaattaa cttttttcta atatggatac tatcttatct tttatttatt
    40561 atagaagtga gtataagcct tactatagaa aaaggtgaag caacaattga aaatatattc
    40621 atagtggcaa taatgtattt tacatactct caactatggc tgtttgtagc tataaaagga
    40681 atgatagagt atctaaaaga tataattttt aaaagagagg ttaaatggta taaaacagaa
    40741 agattttgat tcatgtacag gaggaattaa catgaaaaaa tttattatat caattatatc
    40801 tttagtattg tttttttcaa atatatcact tatatacaaa gtaaatgctg atgagactaa
    40861 agttaaaaat tataagtttg aaagagatat aactattgat ggtgttatag gaagtaatag
    40921 tacttttttt gaagtaaata aaaattggga tattgaagaa gttttattgc atcttaattt
    40981 tagtaagagc caaatattaa atggagatgt ttcaagttta actgtattga taaataatgt
    41041 accaataaaa tctattaaat taaatgctaa gacaaattat aaaaatacat tagaagtatt
    41101 agttccaaaa gattatataa ttcaaggata taatgaaata aaaataaaaa catacaaaac
    41161 aatatctgat aaaatttgcc aagatgattc caatactggg aactggatgg ttattcacaa
    41221 agaatcatat atatcaatta gatataagca gaaaaaggtg gaaaactcaa taaatgaata
    41281 tccgtatcca tatgcagaaa ttgaaaataa tcataaatta gatacaacta tagtagtacc
    41341 agataatatg actagaggag agactacagc agtgtttaat ttggcatcag catttggaaa
    41401 aataacaaaa aatgatgatt taaagttaga tgttaaatta tattcagaaa tgaaaaattg
    41461 gtcagatgat aatattatat atattggtaa acctgaaaat acagcagaag aaattttgga
    41521 tattttaagt ataaaggaac aaaccctatt atcttcaaac tgtataatca agcaagtaga
    41581 ttcaccatac aataagaata agaagatgat ggtggtaatt ggtagtaatg aagatgattt
    41641 aataaaggca tcaaatttat taatagaaaa tagactttct aaccaagttt tatcatcatc
    41701 agtacttgta aacaaagaga ctaatataaa aattaatagg gaacaaaaat taaatttagg
    41761 tcatttaaca ttaaaagact taggatattc tgactttttg ttggaaggag catttaatca
    41821 acaagctttg tttgatgtca aaataccaac gggtaaggta ttagatgatg gttcaaagat
    41881 tatcttaaat ttaagatatt ctgacaattt agattttgaa aaatctttag ttacagtgtc
    41941 tataaatgat gttattgtgg gaagtaaaaa attggatagg tcacattcta ataatgataa
    42001 gttagaatta aaaataccta aagatataga taataaaaac tattatcaag ttaaattgac
    42061 atttaatttg agtataaaaa attcgaattg tgttactaga gagagtaata atccttgggc
    42121 atatgtatca aataattctt atttggcgtt atctatgaaa gaaaatgaaa ccttatcttt
    42181 tgaaaattat ccgtatccat ttgttagaga tgatgaattt aatgatttaa ctgtgataat
    42241 gccagattat tcagggtcac aagctatgac ttggatgttt agattaggtg ttactttagg
    42301 tgcgaatata aattcacata atggaaatat aaatgtaatt agaggaaaag aatttagtga
    42361 caagtataag gatactaata ttgtagtttt tggagtgcca cataataatt ctgttataaa
    42421 gatgttaaat aataatttaa atataaaatt cgataaaaat tactccaatt ttatatcaaa
    42481 tgataagata agctttattg atgattatgg aaaaaatatt tctaccattc aattaataaa
    42541 atcaccatat aataatcaaa aaaatatcat ggtaattagt tcaatgaatg aaaaaaactt
    42601 atatttagga atggattatt tgttgaataa aagtaaagtt aatgatttaa aaggagatac
    42661 attgataatt gatgaatacg gagaggtaga agatttagct tataatttaa aatctaagaa
    42721 agaagtaaaa gattcaagtt ggaatatgag tataaataag acaactaaag tatttttaat
    42781 gatttctttt attactataa ttgtagtcat gatattatca atgctatata taaaaaaata
    42841 taaaagaaga taatatgata aatttattat tttaaaagag gtatataatt tgaggaaata
    42901 tatgaataaa tttaaattaa aaagaagtat tttaatctca ttaataatct taatttttat
    42961 atttatagtt tactttgtaa gtattgagtt aaaagatagg agtctagtaa ataatcaata
    43021 taaaggtaag attaaatcgg ccaatttatc tgtagattat gaaataaatc aagttatgaa
    43081 ggatatagat aaattgggat tgaatacagt aaatgtacct ataattataa atgtagagtc
    43141 cattaattct gatattatgt caatagataa taatagtaaa gaaaaggcaa ttaagttaat
    43201 aaaaaaatta aataaaaaag gtatttcaac aatattagag gcatatccat ggattgaaaa
    43261 tggaaaattg tatgagactg actggaaccc tataaataaa aaaagatttt tttatacttg
    43321 gcaaaatgcc atattaaatg aacttataat tgatgtagca aatccactgg atgtaaatgt
    43381 tttaaatatt ggttctaatt ttgtacattt ggaagaatat caacaaaatt ggggtgaaat
    43441 aatagatttt gtacaatcca aatttgacgg ttttgtaacg tacagaacta attggtggta
    43501 tacaaaaaaa gatgatttaa gtagtaagtt gttttatgaa caaaagctga acaataattt
    43561 ttttgataag ttagatttta tatctatagc agcatatttt gagttaagta ataaacctgt
    43621 taatacagtg gatgaattaa tttctgcctt acactcatct actgtaaaca atagaggaca
    43681 aaatataaaa caagaaatat ataaccttta taaagctcat agaaaaccta tattttttgg
    43741 agaattaggt ttttcaaata gagaaagtgc aagttctcag ccgtggaatc atactccttc
    43801 aaaagctgta aatggcgaag aacaagcaag gtgttttgag gcatataaga aagtttttga
    43861 aaatgaagac tggataaatg gtttttctgt gttttgtgta ggtaaaatag atgacgaaaa
    43921 aaatttttac ccatcaaaag agagtataaa agttattaag tcttggtatg aataattttg
    43981 aaagtgtaga atttatatag attaaataga tgattaggag agacataaat gaatgacatc
    44041 aaggttatga ctgtatttgg aactagacct gaagctatca aagtagcacc tttaataaag
    44101 gaacttgaaa aaagagagaa tataaaaagt attgtttgcg ttacagctca acatagagaa
    44161 atgcttgacc aagttataga aacctttaat ataaatgtag actatgattt ggatataatg
    44221 gaaaaaggac aaagcctgaa tgatataaca tgtaagattt taaataaact tcccttgatt
    44281 ttaaacaagg aaaatccaaa tataatattg gtacatggag atacaaccac aactctagct
    44341 acaagtttga ctgcatttta taataaaact cttgttggtc atatagaagc tgggcttaga
    44401 acctatgata aatattctcc ttttccagag gagttaaata gacaacttac aggtattatt
    44461 gctgatatgc actttgctcc tactaatttg gctagaaaaa acttgatttc tgaaggaaaa
    44521 cctaataata atatatttgt aactggtaat actgctattg atgctttaaa gatgacaata
    44581 aaagaaaact ataatcatcc tataattgat gagattggta acgataggat gattttacta
    44641 acctctcaca gaagagaaaa tttgggtaaa cctatgaaaa atatatttag agctataaag
    44701 cgaatagtag atgactttga agatgtacag atagtatatc ccatacattt aaatcctaaa
    44761 atacgaacta tagctgatga gatatttgga aaatttcctg aaaaaattca tattatagag
    44821 cctttagatg tagctgattt tcataacttt ttaaataaat cttatatgat aatgactgat
    44881 agtggaggaa tgcaggaaga agctccatca ttaggtaagc cagtccttgt gttgcgtgat
    44941 aaaacagaaa gaacagaagg aattgaagca aagacactta aattagtagg tactaatgaa
    45001 gatagaatat ataattcagt gagcgattta ttaataaata aagataacta tgttcagatg
    45061 agtaaagcat ctaatccata tggagatgga aatgcaagca aatatatagt ggatataata
    45121 attaaaaaat ttaattgcaa atatttaaat tagataagac ctaaaacatt aactaattga
    45181 tataagattt atgataatat taaggaatac aatttttaag ggggagtaat atggctagaa
    45241 aattaataaa aaatttgggt aaaagtaaaa gtgtaaagag agtgaaactt ttatttaaga
    45301 agatttttat tactgtattc atagtagcaa gtatagttgc tatttttaat ataacgaaat
    45361 attttgagga attatacaaa gtaagggatt taaaaagtac taaaattgaa tactatatgg
    45421 atgtggctga tgaagcagga gatggaaagg tccaattaag ttggaaggcc ttacttgcta
    45481 tagacatggt aatacatgat gaagatttaa gtaatataaa aaagaaagac acattggata
    45541 taggggaaaa gtttatagta gaagataaaa atgataaagg cgaaaaggtg tataaggtaa
    45601 aaaagtttaa taaggtatta agcgaattga aatttgactc ttctcaaaaa agtagagcaa
    45661 gaaaatacat gaaagattta gaatacacat accttggaaa taaacaatta gatagtagtg
    45721 atgaaaaaat taaatttata aagaagttag aagactcagc tataagagaa tatattgatt
    45781 atggaatatt gccctctata acaattggac aagctatatt agaatctggt tggggaaatt
    45841 ctaaacttac aaaacagagt aataatttat ttggtataaa agcagataaa gcatggaaag
    45901 gaaaaagtgt agaaatttca acttcagagc attataatga aaaaattgta gctagtttta
    45961 ggtcgtataa ttcattacaa gattctgtca aagaccacag tttattttta attaataata
    46021 aaagatatag aaaacatgga ttgtttgagg caaaagatta tattagtcaa gctcaatcat
    46081 tagaaaatgc aggatatagt acagcagaag ataaaaaagg aaatcgtata tatgcagagc
    46141 tattaataga tgttattagg agttataatt tgcaattgat agataataaa gttgagacaa
    46201 aataattgtt aactttatat gaggagataa caagataaga ttcttttcta caaaaagaat
    46261 agaaaaattg taaaaaaaac taaaaaaatg tattgacttg ttatttaaaa ggtgatatta
    46321 ttattactgt actcgaaaga gaacaaaa
//
LOCUS       DAGQVA010000023        45849 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.023, whole genome shotgun sequence.
ACCESSION   DAGQVA010000023 DAGQVA010000000
VERSION     DAGQVA010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45849
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.023"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            204..863
                     /gene="cprR"
                     /locus_tag="MIV85_001470"
     CDS             204..863
                     /gene="cprR"
                     /locus_tag="MIV85_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBY2960816.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1074..2132
                     /locus_tag="MIV85_001471"
     CDS             1074..2132
                     /locus_tag="MIV85_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBY2960817.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2383..4527
                     /locus_tag="MIV85_001472"
     CDS             2383..4527
                     /locus_tag="MIV85_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2797..2799,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HBY2960818.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4576..5409
                     /gene="fdhD"
                     /locus_tag="MIV85_001473"
     CDS             4576..5409
                     /gene="fdhD"
                     /locus_tag="MIV85_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBY2960819.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5420..5593
                     /locus_tag="MIV85_001474"
     CDS             5420..5593
                     /locus_tag="MIV85_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960820.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5651..6202
                     /locus_tag="MIV85_001475"
     CDS             5651..6202
                     /locus_tag="MIV85_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBY2960821.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRQCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6227..7603
                     /locus_tag="MIV85_001476"
     CDS             6227..7603
                     /locus_tag="MIV85_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBY2960822.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7603..8118
                     /locus_tag="MIV85_001477"
     CDS             7603..8118
                     /locus_tag="MIV85_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBY2960823.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNLDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8196..9479)
                     /locus_tag="MIV85_001478"
     CDS             complement(8196..9479)
                     /locus_tag="MIV85_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBY2960824.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9667..10089
                     /locus_tag="MIV85_001479"
     CDS             9667..10089
                     /locus_tag="MIV85_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBY2960825.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10191..11129
                     /locus_tag="MIV85_001480"
     CDS             10191..11129
                     /locus_tag="MIV85_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBY2960826.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11315..13339
                     /gene="ligA"
                     /locus_tag="MIV85_001481"
     CDS             11315..13339
                     /gene="ligA"
                     /locus_tag="MIV85_001481"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBY2960827.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13499..14848
                     /gene="rph"
                     /locus_tag="MIV85_001482"
     CDS             13499..14848
                     /gene="rph"
                     /locus_tag="MIV85_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBY2960828.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKIIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNIPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14848..15318
                     /locus_tag="MIV85_001483"
     CDS             14848..15318
                     /locus_tag="MIV85_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBY2960829.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTHMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15512..16798
                     /locus_tag="MIV85_001484"
     CDS             15512..16798
                     /locus_tag="MIV85_001484"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBY2960830.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16948..17532
                     /gene="clpP"
                     /locus_tag="MIV85_001485"
     CDS             16948..17532
                     /gene="clpP"
                     /locus_tag="MIV85_001485"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBY2960831.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17551..18801
                     /gene="clpX"
                     /locus_tag="MIV85_001486"
     CDS             17551..18801
                     /gene="clpX"
                     /locus_tag="MIV85_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBY2960832.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18872..19399)
                     /locus_tag="MIV85_001487"
     CDS             complement(18872..19399)
                     /locus_tag="MIV85_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBY2960833.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19387..19899)
                     /locus_tag="MIV85_001488"
     CDS             complement(19387..19899)
                     /locus_tag="MIV85_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBY2960834.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20079..22442
                     /gene="lon"
                     /locus_tag="MIV85_001489"
     CDS             20079..22442
                     /gene="lon"
                     /locus_tag="MIV85_001489"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBY2960835.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22432..23043
                     /locus_tag="MIV85_001490"
     CDS             22432..23043
                     /locus_tag="MIV85_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBY2960836.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23309..24679)
                     /locus_tag="MIV85_001491"
     CDS             complement(23309..24679)
                     /locus_tag="MIV85_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2960837.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFVGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24854..24969)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25257..26336
                     /locus_tag="MIV85_001492"
     CDS             25257..26336
                     /locus_tag="MIV85_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2960838.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26728..27408
                     /locus_tag="MIV85_001493"
     CDS             26728..27408
                     /locus_tag="MIV85_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBY2960839.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27401..28780
                     /locus_tag="MIV85_001494"
     CDS             27401..28780
                     /locus_tag="MIV85_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBY2960840.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28951..30036
                     /locus_tag="MIV85_001495"
     CDS             28951..30036
                     /locus_tag="MIV85_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBY2960841.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKAKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30090..30449
                     /locus_tag="MIV85_001496"
     CDS             30090..30449
                     /locus_tag="MIV85_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBY2960842.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30502..31374
                     /locus_tag="MIV85_001497"
     CDS             30502..31374
                     /locus_tag="MIV85_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBY2960843.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYISNIGMII"
     gene            31375..31818
                     /locus_tag="MIV85_001498"
     CDS             31375..31818
                     /locus_tag="MIV85_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960844.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSRHTLPTTDKTREKFSKIKLNEIKKIYETIGINIITKISIDK
                     NKLEIEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31833..32417
                     /locus_tag="MIV85_001499"
     CDS             31833..32417
                     /locus_tag="MIV85_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960845.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANLLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32670..33707
                     /locus_tag="MIV85_001500"
     CDS             32670..33707
                     /locus_tag="MIV85_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBY2960846.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33788..34153
                     /locus_tag="MIV85_001501"
     CDS             33788..34153
                     /locus_tag="MIV85_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960847.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34158..34475
                     /locus_tag="MIV85_001502"
     CDS             34158..34475
                     /locus_tag="MIV85_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960848.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34523..36127
                     /locus_tag="MIV85_001503"
     CDS             34523..36127
                     /locus_tag="MIV85_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960849.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36251..37879
                     /locus_tag="MIV85_001504"
     CDS             36251..37879
                     /locus_tag="MIV85_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBY2960850.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTSLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAALDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNIYFSEEGQSELD
                     VMYNRVVSAYTYALESMRSDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38144..39493
                     /locus_tag="MIV85_001505"
     CDS             38144..39493
                     /locus_tag="MIV85_001505"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBY2960851.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39649..40728
                     /locus_tag="MIV85_001506"
     CDS             39649..40728
                     /locus_tag="MIV85_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBY2960852.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            41073..41981
                     /locus_tag="MIV85_001507"
     CDS             41073..41981
                     /locus_tag="MIV85_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBY2960853.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41986..44355
                     /locus_tag="MIV85_001508"
     CDS             41986..44355
                     /locus_tag="MIV85_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBY2960854.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKQDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44680..45483
                     /gene="proC"
                     /locus_tag="MIV85_001509"
     CDS             44680..45483
                     /gene="proC"
                     /locus_tag="MIV85_001509"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBY2960855.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
BASE COUNT        18813 a         4838 c         8284 g        13914 t
ORIGIN      
        1 tttttatatt taagtaaata cgtgtaaaat gaatataaag tttttgaaat ataaagtttt
       61 tgtatctaaa atattttatt tgtaaaatag taattaatta ttgtaagcta taatatgaga
      121 gtattatggt taatgtgaat tttaaagata ttattaaata tataaattag aatactatta
      181 aacggataaa tggaggagtt attatgtcta agatattagt agtagatgat gagttagata
      241 tgttaaagtt gattgaaaat gtgttgaaaa gagatggaca tgaagtaaag gtaattagtg
      301 atgtagaaaa agctatgaac atggatttta attattttaa tctaataata ttagatgtta
      361 tgatgcctaa gatggatggt tttgaagtat gtaaaactat aagaaataag gttgattgtc
      421 caatactgtt tttgacagca aaaaatatgg aaagtgatat tatgtacggt cttggtatag
      481 gtgcagatga ctatataacc aaaccttttg gtgtaggaga attaagggct aggataactg
      541 ctcatttaag gcgagaaagt agagaaaaaa agaatttatt aactatctca aatgttcaat
      601 ttaacttttt aggcaaagaa gtttcaattg atggtaaaaa aattaatttt actaaaagtg
      661 aatatctaat atgtgaattt ctagcaaaaa ataagggaca agtattttca aaagaaagaa
      721 tatatgagtc ggtatatggt tttgatggag aaagtgatat aagtactatc acagagcata
      781 taaaaaatat acgaagcaaa ttaaaacaat atgatattta tacaatagaa actgtatggg
      841 ggatagggta taaatgggtg taataagtat aagtgttgtt tagtgaaaat attatatata
      901 tctacaaaat gtttgtaaaa tattaatcta tatattaaaa tttaatttat agattaatat
      961 tttttgtaaa tgacaaaatt gtaaggtatt ttgttataaa atattaagat tcatagtgta
     1021 tactaataat atagtattta gtataaatct tgagcaaagg atggttattt ctaatggata
     1081 gactaaagaa tattagaaag agtttactac agtatacatt tttatttttg ttaataggta
     1141 taacaattta cctagtgttt aaaacattgg atattaaaat gctatcaaat gttatggtta
     1201 tggtagataa gaagttttta ttcataggtg ctttggcaat aatgtgtcac ataatgcttg
     1261 aaggagtagt aatgaagata attatagaaa gcactcacaa agttaatatt agatttattg
     1321 gttttaagct agccattatg ggattttatt ataatttaat aactcctttt gcttcaggaa
     1381 gccaaccagt acagatatat gtacttaaaa aatgtaaaat gccacttagt aaggcaagtg
     1441 cagttgttac caataagtct attatcttcc aaatagtagt tactttttat tgtacaatac
     1501 ttgttttaat gaattttgct atgttagaaa aacaaatgaa aatgattatg cctctagtgt
     1561 ttctagggat agccattaat tcatttgtct taattatgat aatattagtt attttaaatc
     1621 ctaaaaaaat aaaatatttt atgagaatta ctataaagca tttatcaaaa attaagtttt
     1681 taaaattttt agataataag attgaatcca tagaaagttt tatagatgat tatagtaaag
     1741 caataaattt ttttgcaaag aataaaaagg tattaatttc aactataata gtaactttta
     1801 ttcaattaag tgcttacttt agtgtttcat tttggatata taaagcattt aatttacaag
     1861 gttatagcta tatttatata ctgacattac aagcattttt atatatggca atatctccaa
     1921 taccaacacc tgggaatgta ggagctaatg aattagcctt tttcactata ttcaaatcag
     1981 tattccctca acctttgatg ggatatgcag tatttttata tggtggattt atgtactatt
     2041 tgattctgat tggaagtgga atatttactg taattactca ctatagaatg aaaaatagaa
     2101 ttggcagaaa tattgtttta agtgaaaact aaataagttt aaagaatata tattgagtat
     2161 attaaaaaat atgtcataag aactagaata ttttaattaa atggttgaaa tataaagatt
     2221 attatgacat attttttttg aaatttaaga ggaattgtga gaaaattgtt gaatttaata
     2281 gatagtattg caaaatattt atgattttgc atattataaa aacactcatt atctttaaga
     2341 taaattttac ttatcagggg ataaatctaa ggggggaatt gtatggagaa aaaaatttta
     2401 acagtttgtc catactgtgg agctggatgc caattatatc tagtagtaaa agataataag
     2461 atattaagag ctgaaccggc taatggtaga acaaatcaag aaagtttgtg tttaaaaggt
     2521 cgttatggat gggattttct aaatgaccct aaaattctaa cacctaggct aaaaaagcca
     2581 atgataagaa aacaaggtgt actagaagag gttgaatggg atgaggctat aaactataca
     2641 gcttcaagac taaatgaaat taaagaaaaa tatggtcctg attctattat gggaacaggt
     2701 tctgcaagag gacctggtaa tgaagcaaac tatataatgc aaaaatttat gagagctaca
     2761 ataggaacta ataatgttga ccattgtgct cgtgtctgac atgcaccatc tgtagccggt
     2821 ctggcttact cattaggtag tggtgcaatg tctaattcta taccagagat agaaaatgca
     2881 gatgttttat ttatatttgg atataatgga gcagattcac atccaatagt ggcaaataga
     2941 atagtaaaag ctaaaaaaaa tggtgctaaa ttaattgtta ctgaccctag agtaactgaa
     3001 tctgcaagaa ttgctgatat acatctacct ataaaaggtg gaacaaacat ggttttagta
     3061 aatgcttttg gaaatgtatt aatagaagaa ggtctttaca ataaagaatt tgttcaaaat
     3121 catacacaag gatttgatga gtataaagaa attgttaaac catatacagc taaatatgct
     3181 gaaaagatta caggaatccc agaagagctt ataagaaaag ctatgagaga atatgcaaaa
     3241 ggtaaaaaag ctatgatact ttatggaatg ggtgtctgtc aatttggtca agctgttgat
     3301 gtagttaagg gacttgcatc aattgctcta cttacaggta attttggtag agaaagcgtt
     3361 ggaataggac ctgtacgtgg acaaaataat gttcaaggag cttgtgatat gggagctctt
     3421 cctaatgtat atcctggcta tcaaaatgta actgatgata agataagaga aaagtttgaa
     3481 aaagcttggg gggtaaaatt atctcctaat aatggttata gtttaactca agttccaaat
     3541 ttagtactaa aagagaaaaa gcttaaagct tattatatat ttggagaaga cccagtgcaa
     3601 agtgacccag atgcatcaga agttagagaa gcattagatg aattggaatt tgtcattgtt
     3661 caagatatat ttatgaataa gacagcactt cacgctgatg ttatacttcc agctacttct
     3721 tggggagaac atgagggagt atatacatgt gcagatagag gattccaatt gatgagaaaa
     3781 gctatagagc cacaaggaga tgtaaaacca gactggcaaa ttataagcga aatttctaca
     3841 gcaatgggat atcctatgaa ttataaaaat actaaggaaa tatgggacga acttagacaa
     3901 ttatgtccaa gtttcttagg tgctacttat gaaaagatag aaactcaagg atgcgttcaa
     3961 tggccttgta agagtgaaag tatggaagat aaaggaacta tgtatctgta tgaaggtcaa
     4021 aagttttcta ctcctaatgg taaaggtaat ttgttcgctg ctgaatggag accccctatg
     4081 gaagttgaag atgatgaata cccatttagt ttatgtactg taagagaagt tggacactat
     4141 tcagtaagaa caatgactgg taattgtaga acacttagtt cattagaaga tgaaccagga
     4201 cgtgttcaaa taaattctaa tgatgctgaa aaattaggaa ttgaagatga tgaattagtt
     4261 agaattagtt caagaagagg aagtgtaata acaagagcaa cagttactga tagagttaag
     4321 gaaggtgcaa catatatgac ttatcagtgg tgggttggag cttgcaatga acttacaata
     4381 gcaaatttag atcctatatc taaaacacca gagtataaat attgtgctgt taaacttgaa
     4441 aaacttgaag accaagaatt agcagaaaaa tgtgtaagag aagagtatca aagtttgaaa
     4501 gacaaaatga cagctacaaa tatctaatga tttattagat ttaagattta taaaaggcag
     4561 aaaggctaat attttatgaa caatatatac tcaaaaacta aattacaaga aaatagtaag
     4621 gataaagttt ttgaaaatag ttatagtcta gtggactaca aatatttaaa ttcttttaat
     4681 gtagaagtaa gcaaaataaa tgaacatgaa gtatcaatag ataatgaaga aataattgca
     4741 gaatatccac ttagttttat tttaaatgat aaatatataa atacattttt atgtacccca
     4801 tataatttag aggaacttat agtaggattc ttgaaaacaa aaggatacat agaaaacaaa
     4861 aaaagcttat taaaatttga gataaatgag agtgaacgtt ttgcaaaagt aactattcaa
     4921 gagaaacaaa aaaatcaaga tgagcaaatt atatttttaa attcactaga ctatataaca
     4981 tgtgctcctg taaagagcaa tataaaaata aattatgata cgatttacag tataatggat
     5041 agaaatttaa attcatcaga attatttaaa aatactggtg gggtacatag cgtatctgta
     5101 tttaattttg ataaaaaaat agtcacttgt gaagatgtag caaggcataa tgcaatggat
     5161 aaggctattg gattttgtgt tttaaatgac ataacattaa aagataaaat tgtggctgta
     5221 agtggaagaa tatcattgga aatgatatta aaagcagcta tgactcaaat tcctattgta
     5281 gtatcaaaat cagcaccgac taatttatca atagagcttt ctaaaaaatt aaatataacg
     5341 cttattggat ttgtaagagg aagacggatg aatatttatg caaatccaca gagagttatc
     5401 aaaaagtgag aatgaatata tgtgtactaa aaaagaagag caaagatatt caaagtgtga
     5461 aatctgtgga gtattaattg atgatactga taaggtgtat aataacacat acaatttgtg
     5521 caaaaaatgt aaacgaaata taagtactga gaaaatagtg aaatatataa atatatatga
     5581 tgaaagtaag tagacatatg atgaaaataa ctagagggtt ggaaatatac aaattgaaag
     5641 gtgggataat atgaaaaata aaataggctc ttttgtaata gcagacccaa acaaatgtac
     5701 aggttgtaga gcttgtgaag tagcttgttt tacaatgcat aatcagcata ataatgtggg
     5761 ttatacagtt ggaacagttg atatacctgt tatacctaga ctttacttag taaaaggtga
     5821 caatttctgt atgccaatac agtgtagaca gtgtgaagat gctccttgtt taaactcatg
     5881 tccacaaaaa gctatagtta aagaaaacaa tattatgtct gtaaatgaag aaaagtgtat
     5941 aggatgtaaa acttgtctgc tagcatgtcc ttttggagct atagacttac ttccacaata
     6001 tgaagatggt aaagaagtag aacaagtaat tttagatgaa aataagaaga tagcttataa
     6061 atgtgactta tgtaaagaca atgaaaaaat agcttgtata agtgcatgtc ctcaggaagc
     6121 attaaaactt gttactccaa tagatgacaa aaaagctaag aatagacaag ctgcacttag
     6181 tttattgtta acaaataaat aaaggataca ggggtaggtg acgtttatga taataaatat
     6241 agataaggat ttatgtactg gatgtagaga atgttcaaag gtctgtccag taaatgctat
     6301 tgaaggtgaa gagggaaagc cacaagagat aaatttagat agatgtgtta tgtgcggtca
     6361 atgtgttcaa acttgtaaat cttatgcttc agttatagat gaaggatttg agtttttaca
     6421 agagaaaaaa caagaaagag agataccaga gtctataaat gaacctatat ttgcagcata
     6481 caatgtatgt gatatagata aggtgaagaa agctttaagt gacccaaatg tattcactat
     6541 ggtccaatgt gcaccagcag ttagagttgc tttaggagaa gatttcggat attatttagg
     6601 atacttaggt gctgggaaaa tggcagcagc acttagagct ttaaattttg atagagtcta
     6661 cgatactaat tttgcagcag atttaactat aatggaagaa ggtagtgaat taattaaaag
     6721 agtgacagaa ggtggaactc ttccaatgtt tacatcttgt tgtccagctt gggtaaaatt
     6781 catggaaaaa aattatccta aattaactaa tcatttatct tcttgtaaat cacctcagca
     6841 gatgggtggt gcaatattta aaacttatgg tgcagagata aataatgtag atgcatcaaa
     6901 gatatttagt gtttctataa tgccatgtac atgtaaaaaa tatgaatgtg atagagaaga
     6961 aatggattct agtggatata gagatgtaga tgtagtatta actactagag aactagctta
     7021 tttaataaaa gacatgggaa ttgattttaa aaatttaaga gaagaaaaat ttgatagtcc
     7081 tttaggtagt tatagtggag ctggaactat ctttggtgtt actggtgggg ttatggaagc
     7141 tgctataaga acaggatatg agcttataac tggagaaagt attcctgatg tagaagtaaa
     7201 acaagtaaga ggagaaaatg gttttagaaa gtcaactatt aaaataggag acttagactt
     7261 aagagttgga gtagtaagtg gattaaaaaa tgtaatacca gtgcttgaag acttggaaaa
     7321 aggaaaatta gatgtagatt ttattgaagt tatgacttgt cctgttgggt gtgtaagtgg
     7381 tggaggtcaa ccaaaaattt tactagaaga atataaggaa ttggcttatg aaaatagaac
     7441 aaaagcaaca tacgtgcatg atgaacattt agcaattaga aaatctcatg agaatcctga
     7501 tattaaaaaa ctgtatgatg aatatctggt agaaccatta ggagaaaaat ctcatcatct
     7561 attacacact acatattgta taggaaagga agtggctaag tgatgaacta ttttgttata
     7621 gcagaccctg ataaatgcat aggatgtaga acttgtatga taggatgtgt agttgcacat
     7681 tcagatgaag atatttttta ccaaaatcta gatgaaataa attttaatcc aaaactttct
     7741 gtcataaaga caaaagaagt aagtgctcca atacagtgta gacattgtga agatgctcct
     7801 tgtgcaaagg catgtccaaa tggtggtata gttagggttg ggaacacaat aaaaataaat
     7861 gaagaaaatt gtataggatg taagacttgt atgttagcat gtcctatagg tgcaatagac
     7921 atagttacat taaaagatgt agatgaagga aagctttgct ttagagaaag aatgacagca
     7981 aataagtgtg atttttgtat agaatcgcca gaagggcctg catgtgtaaa tgtttgtcca
     8041 actaaggcat ttactatagt taaggatgag gatatagata gtaaagttaa aaataagaga
     8101 aaattagcta tattgtaata taaaaaagat ggagttttat ttatgattaa aagctccatc
     8161 ttttttatta taatatttat atatctaaaa atcaattatt gcattagttt atctaatctt
     8221 tctttattca attttttcat tcctatagaa gttataataa gtaaagtata ggcaattata
     8281 actgataaaa ttataataga ccaagaaaat ctgtatccaa aattatcaac taacaatcca
     8341 aataatgttg aacctaatgc aaatcccact gcaaaaatta attgtacgat tccatatatg
     8401 ctaccaaact ccttttgacc aaagaaagag ccagttaaat aagcaggacc aatcatataa
     8461 gcaaatacag aaagaccttt caaaatggca aatacaaatg caaaagtaga agatttatct
     8521 accaatagta atgataaagt tgctataaga accaatacaa aagatataat aagtggcttt
     8581 gtttgaccga atttatcaaa caataatcct ccaaataaat taccaatgag agcaaataaa
     8641 gcaaatgtgg agcctactgt tcctattaga ataggattta gataatttct aagataagtt
     8701 ggatattgta cggataatga tgaaacatat ataccaacaa atataaatcc aatagtcata
     8761 atccaaaaat atttaatttt tttagcttct tttaatgtat aaccccatac tgaaggagaa
     8821 attgtatcag atgctttctc ttttttacct ttagatttta ccttttcatt aatatcttta
     8881 ggcatcctga gtatgaataa tattacaggt ataccaacta ttaatgctat aattccaaat
     8941 attagataag aacgactgta tccttgagtt gctaataagc gaactgcaag tggttgtaga
     9001 aatatactac caatagaacc accagcaaaa gcaaagccca aagcttttcc tttgctttct
     9061 tcatcaaacc aagcacttat taaaacaggt attcctatag cagatataat tgtagcgcca
     9121 atttgaacaa tacatgatac agtgtaaaat tgccatagtt cagtacatat agaaaaagta
     9181 gcaaaagcaa tactagaaat tatacaacct aataaatata gtatcttaat attgacttta
     9241 gaaaataata cacctataaa aggtgatgca attgctgagg caatagtacc aatagtgaat
     9301 attagagaaa aagaagctaa actaaagcct tctccttcta caacataact tataaattga
     9361 ggctgtatac ttgctacaat actaaatgga acagcttgta tcaacataca accaagtact
     9421 ataacccaag catttgaaaa gtttttaatg ctaaatttat tgtttagtaa tgtattcatg
     9481 gtatctctcc tttaggttat gatttgtaga tattaatcta attattctaa ttttatatat
     9541 tagttttgga tagcccaact atttaaatat aatttgggta ttaatataaa aattaactat
     9601 aaaaattgat tattttaaat gtatggggta aattaaagta tataaataaa tgaaaggatg
     9661 gataaaatgt catttgaaaa aataaataat aataacctag ataaaataca caacaggaag
     9721 tgtattatgc ttgtaaactt taataaaaaa gaattatcat taattaaaaa cgtaagtaac
     9781 tttgctggaa taagagacca tatcatctta agtgataaaa atggagagaa tataataaga
     9841 gacattttag atggaaatat atcaaatgaa tgtgaaaatg ggattaagag taagtctgta
     9901 atatttaata acactccaag cacacaagta aatgcatttt tagaagggct aaaaaaagtg
     9961 agaataaata gaccttttac agctatggta acagagacat ctattgattg gacattgaat
    10021 aatttaatag aaaatttagt tcaagaacgt aatgctatgt ctttaggaaa aacaattgaa
    10081 cataagtaaa tttaagatat cttatagtaa ttttaactaa tgtacattga gtatcatatt
    10141 atattttaga atataaaatt ttaaatgtgg gtagatggag gagatttgag atgaaagttt
    10201 tatttacaat aaattatgga aaagaaaaat ttgataaaat aagagaatta ggctatgatg
    10261 tcatacatta ctctgaagat agtattgaaa ataatgagga tgtaaataca gcagatgtac
    10321 tagttacata caatccattt gagagattag atatttctaa gatgaaaaat ttacaatata
    10381 tacagacaac tagtgtaggt atagaccaac ttccaaaaga agaggtattg aagagaaata
    10441 ttaagatagc taataataga ggcggatata gtgtacctat tggtgaaagt attgtattgt
    10501 atattttaga aatatataaa aatagtgcaa aattttttaa acaacaacaa aataaagaat
    10561 ggaagatgga tttttctgta tcagaattgt atggacaaag agttggattt ttaggaacag
    10621 gtactatatc ttcagaagca gcaaaaagat taaaagcttt tggtgtagaa atatggggtg
    10681 tcaatactga tggaagtagt aaaaaatact ttgataagtg ttttgctact gaagatatga
    10741 atattgtatt tgaagaatgt gatatagtag ttgtagcaat gccttctaca aaaagtacag
    10801 atggaatagt aaacaaagat atgtttaaac ttatgaaaga tggttctgta tttataaatg
    10861 taggtagagg aaatacagtt aatcagaaag atttagaaga atgtgtagag aaatttagag
    10921 gggtagcatt agacgtattt gaaagtgaac ctttaaacaa ggacaataag ttgtgggagt
    10981 gcgaaaatgt catagtaact cctcataatt cttgggtgtc agataaaaac aaagagagaa
    11041 catttaatat ggtttataat aatttgaaac actatataat ggagaataaa cctgtagata
    11101 atgttgtaga catatcaaga ggctattaaa aataaaaaat tttgataaaa ataaaaactc
    11161 ttattagtcg tattaaagat actaataaga gttttttttg taataaattt aaagcccaaa
    11221 aagtgatata ctaaaaaata tataaatagg agataattaa ttatagggaa atttcaaaat
    11281 aatttaattt taaaaatatg aagaggtgca aaaagtgagc gtaaaagatg aaattaataa
    11341 acttatagag acaataaact accataatga aaggtattat aatcaagata gcccagaaat
    11401 atcagattat gaatacgata agttaatgaa ggagttaatt tctttagaag aagaacatcc
    11461 agaactaaag agaattgatt ctccaacaaa tagggtagga ggtaagccat tagataagtt
    11521 caatcaaatt gtacataaaa ctcctatgtt gagtttatca aatgcttttt cagagcaaga
    11581 tttgagagat tttgataaga gagttcaaga atatgtggga gaaaatgttg aatatgttgt
    11641 tgaatttaaa atagatggtc tttctgtagg tctaacttat aacaatggag agtttgaaaa
    11701 aggagcaact agaggagatg gagttgtagg agaagatatt tctcaaaact taatgacagt
    11761 aaaaagcata cctcttaaga taaatgataa aaaagaacta atagttagag gagaagtata
    11821 tatatcaaaa gataatttta gaaaagtaaa tgaacaacaa gaagaacaag aacagccatt
    11881 atttgctaat ccaaggaatc ttgcagctgg ttcattgaga caattagacc caaaactaac
    11941 agcaaagaga ccattagata tatttgtatt taatatggaa aatatagaag aatacgattt
    12001 agaaagtcac agtgaatcac tagagtactt agaaaaacta ggattttcag taagtcagag
    12061 ttataaagtt tgtaaaagta tagatgaagt tattgagcat attgaatact ggacagataa
    12121 caggggtaat ttagactacg aaatagatgg tatggtaata aaagtaaaca atataaaaca
    12181 aagagacgaa atgggatata cagccaaaag tcctagatgg gcaattgcat ataaattccc
    12241 agcagaaaag aagaaaacta aaatagtaga tataatagta gaagttggga gaactggtac
    12301 aataacacct tcagcaattc ttgaaccagt cagacttgca ggtactactg taagtagagc
    12361 tacacttcac aatgaagatt atataagaga aaaagatata aaaataaatg atacagtatt
    12421 agttcaaaaa gcaggggaca taatacctca agttttagaa gttataaaag aagaacgtac
    12481 tggagatgaa atagatttta aaatgccaga aaagtgtcca gtttgttcag agccaacaat
    12541 aagattagaa ggagaagctg ctgtaaaatg tatcaatatg tcttgcccag cccaaataag
    12601 aaggggaatt atacactttg tgtcaaggga tgcaatgaat atagatggat tgggagaatc
    12661 tataattaca ctgctattaa atgaaaaaat tattcaagat gtatctgatt tatattatat
    12721 aaaaaaggaa gatgtagtcg acctagagag aatgggcgaa aaatctgctg acaatttaat
    12781 aaattcaatt gaaaaatcaa aagaaaatga tttatggaga cttataaatg gattaggtat
    12841 taaatttata ggagttaaag cagctaagat acttgcatat aactttaagg atttagatga
    12901 agtaatttct gcaactagtg agcaactaga agaattagag gaatttggaa gtataatggc
    12961 aaacagcgtt gtcgagtttt ttaaggaaga caaaaatatg aacgttataa acaagttaaa
    13021 aaatgtagga gtaaatacaa aatcattgga taatacaggt gaaaaagtag aaaaaatatt
    13081 tgaagggatg aaaatcgtat tgactggtac acttcctaca ttaaaaagaa atgatgcaaa
    13141 agatatgata gaaaaaagag gtggaaaagc tacatctagt gttagtaaat cgacaacatt
    13201 tgttttggca ggtgaagaag ctggttctaa acttactaaa gcaaatgatt taggaattaa
    13261 agttatagat gaagagagat ttttagaatt attaaagtta tcatcgaaag atgaagtaaa
    13321 agctgtatta gagagttaaa aagtcgctta atttagtaga aaactactat aattaatgat
    13381 agaatagttc agtaagctaa taagattacg aaaaatgaca ataattaata tttgacaaaa
    13441 ttaaaaatta taaaaataaa tttataaaaa ataaaaaata tgagaaagga tataaaaaat
    13501 gaccagaagt tatgatagaa gtaacgaaca gataagacct gtaaagataa ctagagatta
    13561 tacaaagtat gcagaaggtt ctgttcttat agaaatggga gagacaaagg ttatatgcac
    13621 tgcatcagtg gaagaaaaag ttcctccttt tttaagaaat agtggtactg gatggataaa
    13681 tgctgaatat tctatgctac caagagcaac acaacaaaga aagataagag atgcatctag
    13741 gggaaaaatt gatggaagaa cacaagaaat acagaggtta ataggaagag caataaggtc
    13801 tgttgtagac ttgaataaat taggagaaag aactatttgg gtagattgtg atgtgattca
    13861 ggcagatggt ggaactagaa ctgcatctat aacaggggca tttgtagcag ttgcagaagc
    13921 aatatataaa ttatataaag caaagataat aaaagagatg ccaataacaa attttgtgtc
    13981 tgcaattagt gttggtattg taaatggaat acacatgcta gatttatgtt atgaagaaga
    14041 ttctaaagca caggtagata tgaatataat aatgactgat aagtgtgagt ttgtagaagt
    14101 acaggggaca ggagaagaga aacctttttc gagagcagat ttaaatttat tgttagagtt
    14161 aggtgaaaaa gggaataaag aattaataag gcttcaaaga gaagctttag gtgaaatatc
    14221 agatgagata ttgggtatgg attatggtaa tgaagtagtg attgctacta ataatgctca
    14281 taagctagaa gaaataggtg aaatcttaaa agattttgaa tataaagtgt actctttaaa
    14341 agatgttgat ttagcaggta tagagatagt agaagatgga aaaacatttg agcataatgc
    14401 gttgataaaa gctagaacaa tagcaaaaaa gactaaactt atagcaatat cagatgattc
    14461 tggcttagaa gtagatgctt taggcaaaaa acctggtgtt tattcagcta gatatgcagg
    14521 agaacatgca acagatgaag aaaatagaaa aaaactgtta aaagctatgc aaaatatacc
    14581 aatgagcaaa agaaatgcaa gattcgtctc tgcaatagca gtagtttttc ctgatggaaa
    14641 agaatttgta gtaagaggaa tttgtgaagg aatgatagga tttgaagaaa aaggtaaaaa
    14701 tggttttgga tatgatagct tatttatagt aaaaggatat gataagactt ttggtgaaat
    14761 acctagtgtt ataaaaaatt caatcagtca tagagcaaac gcactaaaac ttatgaaaca
    14821 agagtttata aaaagggtag tgaagtaatg aaaataggca tagtaagcga cacacatatg
    14881 atgattaaaa atatggaaaa aacaatacca tatttgaaag aatgtgacct aataattcat
    14941 gcaggagata actttactga ttcaagatat attcatagca tgactaatgt aggtattatt
    15001 gcagttaaag gtaattgtga ctttgatgct gttgaggaag aagttgtctt tgaagtggca
    15061 aataaaacca tattcttatg ccatggagat aagtatggcg taaaatatgg aactcatatg
    15121 ttagaaaaaa aggcaactga agttgatgct gatatagtta tatttggcca tacccatacc
    15181 ccatttagag aaattaaaga tggtgtactt tacataaatc ctggaagcac ttcacttcca
    15241 agaggagtat cgtataaaag ttttgtcatt atggatatag aagaagatga cataaaaatt
    15301 gaagaaatac gcatataaag gtgtatttat ctaaaaaaat ggcaaaaaac gctcaaaaaa
    15361 ttaaatttta tcaaataagt acaacgatat taatggaaca cttgtaaata aaaaaactta
    15421 tgtgatataa ttaagtggtt gaattataaa tagaatgaat tataataccg ttatcgggta
    15481 ttacataaat atcactagga ggattagaag gatgaaagca gaactaatta aaaaagaggg
    15541 taataaagtt actttaaaaa taacagtaga taacaataaa tttgaagcag cagtaaataa
    15601 ggcttataat aaaagcagaa ataaatacaa tatacctgga tttagaaaag gtaaagctcc
    15661 aagaattgtt atagagactc aatacggaaa aggtatattc tacaatgatg ctatagaaat
    15721 attattccca gaagtttatc cagaagctat caaggaatta gacatagacc caatagacaa
    15781 tccagattta gatatagaag aaataagtaa agacaatggg ttggttatgg ttcttaatgt
    15841 agaagttaaa ccagagtttg aattaggaaa ctacaagggt atagaaatag ctaaggttga
    15901 gaatactgta agtgacgaaa atgttgatgc taaactacaa gaaatggttg aaaaaaatgc
    15961 cagattagta agtgtagaag acaaagcttt agaagatgga gatacagcta taatagactt
    16021 cgaaggtttt gaaaatggtg tagcttttga tggtggtaaa ggtgaaaatt ataacttagt
    16081 tataggttca aacacattta taccaggatt tgaagaacaa ttagtaggta aaaaagctgg
    16141 tgaagaagta gaagttaatg ttactttccc agaagaatat cactcacaag atttagctgg
    16201 aaaaccagtt gtatttaatg taaaaataaa tgatgtaaaa gtaaaagaat tatctgcact
    16261 tgatgatgaa tttgctaaag atactagtga atttgattct ttagatgaat taaaagcaga
    16321 tgtaagagct aagttagaag aagaagctaa aaatagagca gatgcagaaa ctagaaattc
    16381 agtagtagaa aaagttgctg aaaatacaga aatagaaata ccagaagtta tgatacaaca
    16441 tcaaatagat aatatgttaa atgaacttaa ctaccaatta caatatcaag gatttggatt
    16501 acaacaatta ctagagatga ctggtagaac tatggaagaa ttaagagaag agagaaaaga
    16561 agatgctaaa aaattagtta agtcttcttt agtattagaa gcaataacta aagctgaagg
    16621 aattgaagca acagaagaag aatttaaggc tgagttagaa aaaatggctt ctgcttacaa
    16681 tatggaagta gaaaaaatag aagcttcttt aagagatgcc gacaaagaag atataaaagg
    16741 tcaaataaaa ataagaaaaa caatagattt attagttgat aatgcaacaa tagcttaata
    16801 aaataaacgc taactaatat agttgacgtt atgaaatgtt tagtatataa tgatgtgcaa
    16861 atataattta gttaaatgcg tataataatt tacagtagct taaaaaaagc tactgtaaat
    16921 tatatagaat aaagggggta tgaaaccatg gcattagtac ctgtagttgt tgaacaaaca
    16981 ggaagaggag aaagatctta tgatattttt tctagactat taaaagacag aataatcttc
    17041 ttaggagatc aagttaacga tgccacagca gggcttatag tagcacagct attattttta
    17101 gaagctgaag acccagacaa agatatacat ttatatataa attctccagg aggaagtata
    17161 acttctggaa tggctatata tgatactatg caatacatca aaccagatgt aagtactata
    17221 tgtataggta tggctgcttc tatgggagca ttcttgttgg cagcaggagc aaaaggaaaa
    17281 agactagcac taccaaatag tgaaataatg atacatcaac cattaggtgg agctcaaggt
    17341 caagcaacag atatagaaat tcatgcaaag agaattttaa aaataaaaga aactttaaat
    17401 gagatattat ctgaaagaac tggtcagcca ttagaaaaaa ttaaaatgga tactgaacgt
    17461 gataacttca tgagtgcact agaagccaaa gaatatggtt taatagatga agtatttaca
    17521 aagagaccgt agatagagag aggtgttaat atgtctaaat atgaagaaaa acgacaatta
    17581 aagtgttcat tctgcggtaa aaatcaagat caagtaagaa gattaattgc aggtccaaat
    17641 gtatatattt gtgacgagtg tgttgaactt tgtgacgaaa ttattcaaga agagatagaa
    17701 gatactatag atgaggatac tacatcttta ccaaaaccaa aggaaatgat ggagattcta
    17761 aatgattatg taataggtca agaaaaagct aaaaaagctt tatcagttgc ggtttataat
    17821 cattataaga gaatatacag taaaaaatct agtagtaagg atatagaaat tcaaaagagt
    17881 aatatacttt tattaggacc tacaggttct ggaaagacat tacttgctca aactctagca
    17941 agaactctaa atgtaccttt tgcaatggca gatgctacat cattgactga agctggatat
    18001 gttggagaag acgttgaaaa tatactttta aaacttattc aagctgctga ttttgatata
    18061 gaaaaagctg aaagaggtat aatatatata gatgagatag ataagattgc aagaaaatct
    18121 gaaaacccat ctataactag agatgttagt ggtgaaggtg ttcaacaagc acttctaaaa
    18181 atattagaag gtactgttgc aaatgttcca ccacaaggag gaagaaaaca tcctcatcaa
    18241 gaatttttaa agatagatac tactaatgta ttatttatat taggtggagc ttttgatgga
    18301 ttagagaaga taattcaaaa acgtggtgga gataaaacac taggttttgg agctaaaata
    18361 gaaagtaaaa aagaattaga tttagggaag ctatatgaaa aagtacttcc agaggattta
    18421 ttaaaatatg gtataatacc agagtttata ggaagaatac cagttttagc tactttagag
    18481 ttgttggatg aagatgcatt aatgcagata ttacaggaac ctaaaaatgc tctagtaaaa
    18541 cagtataaaa agttattgga gttagatgat gttgagctag aatttgaaga aggtgctctt
    18601 cgtgcaatcg ctaaaaaggc catagaaaga aatacaggag ctagaggact tagaagtata
    18661 gttgaaagcg taatgatgga aactatgttt gaagtaccat ctagagataa tataaagaag
    18721 gttatagtaa cagagaaatc tgtgaacgaa gactcagtaa atcctatcat agtacttaag
    18781 gatcaagagg aaagtgcata agatgatgaa aaggagcttt aaaagctcct ttttttatgt
    18841 taatatgcta aatataaaat aggtatcatt attataaaaa tgtgagtaat atacctagaa
    18901 taccaaagac gaatacaatt gcaatggaac caatttttcc tttatataaa agataaaatg
    18961 atgctataaa tgcaattatt ccatataaat cccaattaac ttctttggca gatgaaaaag
    19021 ctgctgataa tatgaatcct agagtaattg gtctaagaac tgtcaataag ttttctacct
    19081 ttttattatt tttaaattta gaaaataact ttgatataat agttagacct attaatgcaa
    19141 aaattgtaac accaatagtt gcggctagag aaccaaagaa gccagcagtc ttaaatccta
    19201 caaatgtagc actatttatt gctacaggac ctggtgtaga ttgtgatata gcaagtaaat
    19261 ccaaaaactc ttgattagtt ataaagtgat atttagatat aaattcttgc tggataaatg
    19321 gtagcatggc ataaccgcca ccaaaactaa atgcccctat tttaaggaat attaagaaga
    19381 gtagtattat ttctgacata gactatatac acctcctcca attattaaat aaatagggct
    19441 tatattgaat acaccaacag ataaaactgc tataattaat agtagtatgt tagttttaga
    19501 ctttggtagt ttcttgaaca tgctcgtaaa agaatacaat ataagagcta ttacaacagg
    19561 cgcaactcct ttaaaaaatc catctaaaat tttagatgat gaatttttaa agtatagata
    19621 cgataagact aagactatac aaaatgatgg taaagcagag cctaaggtac atataagaac
    19681 tcctggtata ccataaagtt tatatcctaa taatacagat atattaactg ccagtactcc
    19741 aggataactt tgagctatgg ataaataatc aataaattct tcctgctcta aaagtttttg
    19801 tttgtttaca agttcatctt gtataagagg aaccatagcg tatccaccac caaatgtaaa
    19861 cgcaccaatt tttaaaaagg ttaaaaacaa tttcaacata atagaaacct ccaaaagata
    19921 aataacatct aagtatacta atattaatat tatatcataa taaaaagata atatagtatg
    19981 atagtattct aagaatttat cattaatgtt gaaaattaac ttgttcaaat atataatatt
    20041 aaaagcaaag caattagact agaaaaggag taatgttgat ggaacaaaat tatactaaaa
    20101 tagatcatga attaccatta attcctctaa gaggattagc tatatttcca tatatgatat
    20161 taaattttga tataggtaga gagatatctc ttaaagcttt agaccaagct atgatggatg
    20221 aagaacttat atttttaact tctcagaaag aagcagaggt agatgagcca ggagaagagg
    20281 atttttatca tgtgggaaca atctgtaaag ttaagcaaat gataaaatta ccaggagata
    20341 cagttcgtgt tttggttgaa ggtgtatcaa ggggtagagt aaagaaaata gaacaagaag
    20401 atgggtattt cagagcagta atagaagaaa tagtatttga tagtgataat ttggatagtg
    20461 aaacagaagt tgaaattgaa gcatttgtaa gaaatgtatt tgatgccttt gaagagtata
    20521 taaatattgg aaatagggta tcaccagaaa tattaatatc tttagctgat atagaagatg
    20581 tagatagatt tatagatacg atagctgcaa acatatatct aaaatcaagc caaaaacaag
    20641 aaatattaga agaatttgat attagaaaaa gacttgaact tatttattct atattattag
    20701 aggaaataga tatattaaaa atagaaaaga aaataacttt aagagtaaaa aaacagatga
    20761 ataaggttca aaaagaatat tatcttagag aacaattaaa agctatacag aaagaattag
    20821 gtgaagaaga agatataaac tctgaagcag atgagtatag agaaaagctt aaaaaaataa
    20881 aagcacctaa gacaactaaa gagaaaatag aaaaagagat agataaattt tcaaaaatat
    20941 cttctatgtc tccagatgta tctgtaagta gaaactattt agatactata ttctcattgc
    21001 catggaataa agagacaaaa gataaattag atataactaa ggcaaaagat atattagatg
    21061 aagaccatta tggattagaa aaagttaagg agagaatact agagtatcta gctataagaa
    21121 ctcttgctaa gtcacttaaa gggcctataa tatgtctagt tggtcctcca ggaacaggaa
    21181 agacatctat agtaaaatca atcgccagag cattaaatag aaaatttgta agaatatctt
    21241 tgggtggagt tagagatgaa gcagaaataa gaggtcatag aagaacttat gtaggttcaa
    21301 ttccaggaag aataattaat ggggtaaaag aagcccaaac aaaaaatcct gtattcttat
    21361 ttgatgagat agataagatg gcagcagatt ataaaggtga cccagcttca gcaatgctag
    21421 aagtattaga cccagagcaa aataaggatt ttgtggacca ttacttagaa ataccttttg
    21481 atttatcaaa aatactattt gttacaacag caaatagtct aagtaatata ccaagaccat
    21541 tattagatag aatggaagta atagaagtat ctggatatat agaagaagaa aaattaaata
    21601 tagcaaaaaa atacctactt ccaaaacaaa ttaaagaaca tgctttaaaa gaaaacttta
    21661 taaaaataga tgatgaaact ttaagaagta taatcaacca ttatacaaga gaagctggtg
    21721 taagaacact agaaagaact attggtaaga tttgtagaaa ggttgccaaa aaatacgttg
    21781 aagacccaac tcttgaagag gttgttataa ataagtctga cctagagaca tatcttggaa
    21841 aagacatgtt taagtatcaa cttgcagaag ttaaccctca aataggatta gtaaatggtc
    21901 ttgcgtggac agaagttggt ggagttacac ttgaagtaga agtaaacgta cttaaaggta
    21961 aaggcgaaat tgtattaact ggaaaattag gagatgttat gaaggaatct gcgaagacag
    22021 gtatctctta tataaggtca atagtggaca agtttgatat agaccctgaa ttttataaga
    22081 cgaatgatat tcatatacac attccagaag gtgctgttcc aaaagatgga ccatcagctg
    22141 gtataactat ggctcttgca gtaatctcag cacttactaa aagacctgtg cctggaaata
    22201 tagcaatgac aggagagata actttaagag gtagagtctt agcagtagga ggagttaaag
    22261 aaaagttatt agcagctcat agagctggta taacaaaagt attaattcct aaagaatgtg
    22321 aagctgattt agatgaaata ccagaaaatg taaaagaaaa aatggagttt gtgcttgtag
    22381 aacatatgga tgaagtatta gaacaagctt tattaaagag tggtgaaaat aatgaaaatt
    22441 agaagttcag agataactat gagtgctgtg aataaatcac agtatccagc agaaggaatc
    22501 ccagagatag cattggctgg taggtcaaat gttggaaaat catcaataat aaatacattg
    22561 cttaacagaa gaaactttgc tagaaccagt caaacaccag gaaaaactag aactataaat
    22621 ttttatctaa taaataatga attttatttt gtagaccttc caggctatgg atatgcaaag
    22681 atagctaagt ctgaaaaaga aaagtgggga ggtataatgg aacgatatct agaaagtaga
    22741 caagagttat gttctatatt cctacttgta gatattagac atgagcctac agcagatgat
    22801 aagcttatgt atgaatggat aaagcacttt ggatataact gtgtagttat tgcaactaag
    22861 gcagataaaa tatctagagg acaatatcaa aaacacataa gtataataag aaaaaaattg
    22921 caaatggaaa gtagtgaaaa agtaattcct gtttcttcac taaaaaagac tggtgttgaa
    22981 gaattatggg aagagattgt aaatcaatac aatcaacatg gatatgaaat aacagtagat
    23041 taaatttaaa atgttaaata ttgacataag atttatttga ataataaatg taataatagt
    23101 tagttttaat tatattaata ttaaagtaaa atataggatg ccttaaaata gttttaatga
    23161 actttttttt ggcatcctta ttgtttataa acaataaata tcagtaattt tgctaaatac
    23221 taataaattt tagtaaggta tgggaaaatt agtataaaat agttaaacta aaaaattatt
    23281 gatttatgta gtcagtaata aatagcattt aagaaataga tttatctgtt ttcctcataa
    23341 agaaaacagt tagtataagc cctacaaaac atactgatgc tgcaatccaa taagactgat
    23401 tgctagctat aacataggct gatgtgtgac ttttaaactt ttgattgtat gtaagacttt
    23461 gtgcaaaaaa actactaaaa aatgctgttc caagagcaaa tgataaatta cgaatagttg
    23521 caagaaaact gcctccgtac ccctgttttt gaggaggaac atctgctaaa atactactat
    23581 tgtttggtga actaaatgct cctagcccaa gtccaaaaat aactaaacat acaattaaaa
    23641 ggtacaatgg agaatctgct tttaaaagtg ccattccaac tagtgagatg gtcataaatg
    23701 aaaaagatgc tgttagaatg ttttttgcac cgtgtttatc agaaagtgaa cctgcaatag
    23761 gtgctataag taccataata agtggatgta cagtcattac ataaccagcc atcataggag
    23821 ataaattttt taattgttct aaataaaatg gaagtagaaa agatactgcc atttgaggaa
    23881 aataacaagc tactccaatg atattgccta cagtaaagtt tctattttta aatagaggta
    23941 ggtcaataaa gctttgttca aattttactt ctcttaatgc caacaataag aagattataa
    24001 gtgctgttat acctaaatac aatcttgtat tacccttctc attcattgca agtaatataa
    24061 gcgtagtgca agatgcgaaa agtagaagac ctggaatatc aaagctcttg ttttgttcat
    24121 ccaaaacagg tttaggcaga aatttaatgc caagaaagac tgctataata ccaataggga
    24181 tattgataat aaaaatagaa ggccatccaa aatgttctaa aattatacct ccaattacag
    24241 gaccactcat atttcctata ccaactacag ctccagtgat tcctatagct tttccttttt
    24301 catttgctgg aaatgcattg gaaactatac caagcccagt agccattaaa atacttgctc
    24361 caactgcctg aaagattctt gaagaaatta atgttgataa attgtttgac atactacaca
    24421 gaaaagaacc tattgtaaat ataaaaaatc ctaatgtgta tagacgattt gaacctactt
    24481 tatcgccaag ttttccgaaa aataacatag tagctgttac aacaagcata taagctgtta
    24541 caacccactg aatttgtgac atgttaattt taaagtcagc agcaattgta ggatttgcga
    24601 tatttagtat acttccatca agagtagaca taaatacacc aatacagatg ataatcaata
    24661 ctatccattt ttgtttcatg ataacactcc aatcttaata gattttataa gtacgatata
    24721 attgtaaaat aaacaacaaa aaaagcacct gtatattagg taccttgaat gtgtctaatt
    24781 tcatgaataa atacggtagt tgaaggattt gtatagatta ctcatgtaaa attacataaa
    24841 ggtactcata tactattttc ttctaccatc cagattttac tgtcggcttt ggaatatgac
    24901 caaattatgc cataaggctc gcgggctttt accgccgata ggtaatttca cccgtttatg
    24961 aagaaaaaca gatgtatttt gtaatattat tttaacataa aattataatg gaaacaattg
    25021 gatttaagta atatccagct gtattacaat acaaatattt caatatggac acttaaattg
    25081 tatttataga tagaataagg cacagtatga gaatctataa taattagata aaattaacct
    25141 gttattagta ttagatggca agttttaaat ttgtcaaaat cagaaagctg taataaaatt
    25201 cttataatat gaatatctta attaagagat attgtaaatt atgaggaggc gctaatatgg
    25261 aaggaaaggt aaagaaggca ttcccgggtg gaaatacatc acaaggctca tattcttttt
    25321 ttgactatat aattcctgaa aatgtaaaaa gagttttttg tttaaagggt ggacctggag
    25381 taggaaaatc ctcacttatg aaaaaaattt ataaagagtt tttgcataga ggatatgata
    25441 ttgatttata tcattgtcct tctgacccaa gttcgttgga tggtttagtt ataaagaaat
    25501 taggcgtggt acttatggat gcaactgccc cacatactat ggacccaaag ctacctggag
    25561 ctttggatga gataattaat ttaggtgatt actggaatac agaagaatta gaaaagaata
    25621 aacaagaaat atcagtttat gataaagata ttagtaattc atttaaaaga gcatttaagt
    25681 ttttaaaatc agcagaacca atctttagag acatagaaga aaaatattct gattgtatgg
    25741 attatggcaa agtaaatttg gtcacagaag aatttataaa aaggttattt gatggagtta
    25801 aaagcacagg aaatctaaaa agagaaaagc atttatttgg ttcagctata actcctgtag
    25861 ggtgtttaga ttatacagaa aacattttaa aagatgtaaa gaaagtctat tatttagatg
    25921 gagaaatagg aactgggaaa actacattat taaacaaagt atataagaaa gctattgaaa
    25981 aaggtttaaa tgtagaagtt tatcattatc cacttattcc agagaaaatt gaaactgtac
    26041 tattaactga tttagatata ggcataacta taagtacgac ttttaaagaa gaagatacaa
    26101 ttgatttaaa tcagttttta aatagagaaa aactacttaa atatgaagaa gatattaaat
    26161 ttgatgaaaa agttttagat gatttaattt gttgggcagt actaaatctt aagagagcca
    26221 agtctaaaca tgatattata gaaagttact atagtcctaa tatgagattt gatgaagtag
    26281 ggaaattaag agataaatta attaaaagaa ttttaaaata tgaggaaaac ttataaacgt
    26341 atatgtttaa aattaatgtt aataatgata taatttttag taaattggtg tagctttgag
    26401 gctatgccat tttacttttt tttgctaaaa aatgatatta ataatctcca aagcaattat
    26461 ttgtttttca taattattat ttcctttcct aatttatgtt tttttataat atcaaaacaa
    26521 tgtttattga aagtttatat aattttaaga acatctaaaa atgcatactt gatattggta
    26581 aattagtgat aggagttcaa tgtatgatat tatatactaa agatgaattt taatatataa
    26641 ctttgatata ataagcatat gtaaatgttt aatatttaat taaagaaaat tatcatataa
    26701 aaataaattt gtaaggagca atacagtatg aaaaaacaat atgtgtttat aatactagca
    26761 agtactattt taggtatact tgttggaacc atatttagag attatagcaa tgaagaaaca
    26821 gtttatacaa gcaaagacaa gtcaataaga aaagaaataa aaatgacaag aaaatctata
    26881 aaagaattaa ccaaagagaa agacaagtta gataaagaaa ttaattcaat gaaacaaaat
    26941 caaaaaaatt ctgaagaaat atcagaaata gaaacactta gagatagtct atcatattca
    27001 gatgtaaagg gtagtgggat aatattaagt atagatgcta tagatgaaaa aacagggaat
    27061 atagctaata gtatagacta taataagatt cttgtaaaag ttataaatga attaaaagta
    27121 aacggaggaa aatacataga aataaatggt caaagaatta atcaatattc agaagttgta
    27181 cttgcaggaa gccatataaa tataaatgga gttcctgtag cacaaccata tgaaataaag
    27241 tgcattggag ataaggagaa actatctaat tatgtagata aaggtagtaa atatttagat
    27301 agcatacaaa ccaattatcc aatgaaaata agcataaaaa ctgaagaaaa tatctctatg
    27361 aaaaaaatga atatacctaa taaattaaag tatataaagg gtgattaaga ttatattaga
    27421 ggaaagcagt ttgccaatgt taataccaga aaaacttgca aaaaaatata atgtatttcc
    27481 agttgagttt caagatgata atttagttgt agaaatagaa gatgaggata tttatgctct
    27541 acaggacttg agattagcta caggtaaaga aattatattg aagaaggaga aaaaagaact
    27601 tataagtgaa aagattgaaa aatattataa tagctttgaa cttgatgagg attatgcaaa
    27661 aaaattattt gaaaatcttt tagaaaaagc tataaaagaa aacgcaagtg atatacatat
    27721 agaaccattt aaagaacatt taatagtgag aatgagggta gatggagaac taaaggaagt
    27781 atcaaagttt ttagttgatg tctatccatc attgtctacg gttataaaat taaaggcatc
    27841 aatggatata acagaaaaaa ggcttcctca ggatggtagg gtggatataa agttaggtgg
    27901 aaatttaatt gacattagag tttcatcaat accaactgtc tatggtgaaa aaatagtttt
    27961 gaggatactt aatagagata cttttttaaa agacaaatta gaacttggtt tttcagagga
    28021 agctataaaa tctataaatc gtataataaa taaaagagca ggaatattat tagtgacagg
    28081 tcctacaggt agtggaaaga ctacaacagt atattcctta ttaaatgatt taaaaggaat
    28141 aaataaaaat attatgacta tagaaaatcc tgtagagtat aagatggatg gcataagtca
    28201 gattcaagta aattcaaaag tagggttgag ctttgatgta ggtcttagag cgatattaag
    28261 acaagaccca gatataataa tggtcggaga aataagagat gcagaaacag ctaagatagc
    28321 agtaagagca gctataacag gtcatttagt tataagtact ttacatacta atgatgcagt
    28381 atcttccata gctagattac tagaaatgca aataccacca tatcttttaa atgcttctct
    28441 tataggtgtt atatctcaaa agttggttag aaaagtctgc aatcattgta gccatgagat
    28501 tatgataaaa gataatttta gtggagatgt aaatactaag gtagctgtag ggtgtgaaaa
    28561 atgtaatgat aaaggatact ttggaagaac agcaatttat gaaatcttag aaattaatga
    28621 tgatataaag acatgtataa gaaatatgga ggattctagt actattaaag atgtagcaca
    28681 aaataatgga atgataacat ttgaagatag ttgtaaaaga ctaataaatg aaaaaataac
    28741 gacattagaa gagtgtttag tagtaaatga aatgatttaa ctgaattgta tagttaaact
    28801 tcgtttggtc agttgtcttt atttaatcta ttttaattaa gatgtttgag tataaattat
    28861 atttaagtga aataaaatta aatgcattaa attagaaaat attaagttta tttaattgta
    28921 attaatataa tttggaaggt attatagtac atgagattat ctaaaaatat attttataat
    28981 ttagaaaagt tttatttagt attaaataga atcagtgata aagaaattag agtaatttgc
    29041 aaagagatag gcatattgct ggaatctgga tgtgaaatta caaaaatatt tgaaatcatt
    29101 gagagtcagt caagtaaaaa agcaaagaat ttgcttagta tagtatcaaa tcatattcaa
    29161 aaaggtaact caatagcaga atcatttcaa ataacaggta tattttctaa attctttata
    29221 agtatgataa aagcaggaga aactagtgga aacttagata taataatgag tgatttatct
    29281 aattattatg ataaagaata caaattaaaa atgaaaataa taactatttc aatatatcca
    29341 ataatactta taatattatc tatcttatca atgttgttta tattcgtatt tgtaatacct
    29401 aattttcagg tggtttttac caacaatgga attgaaccac ctttaataac tagagtttta
    29461 atgggaatat ctacagtggt tacaaataac ttagcttata taatatttag ttttatattg
    29521 ttttcaatag gaagcattta tttctttata acaaatgata atataaaaaa attgattaat
    29581 tcgttaaaat tcaaaatacc ttttataaaa aaaattaatc agttagtagc tacaacaaga
    29641 ttttcaaggg cattgtccgt tttaattagc agtggaatac aaattgtgga agctatagac
    29701 atgtcagcta gtgttataga caacgaattt atttatgaaa ggttaaagat ttccaataat
    29761 tatataaaaa aaggaaatag cataggtaaa tctttgaatt tagcaaatgt ttttccaaaa
    29821 ttatttattt caatggcaaa tacaggagaa gaaagtggga aactagataa aagtctaaat
    29881 gtaataaata aattttatga aaatgaatta aataacaaaa tagagcaaat aatgaaattt
    29941 atagaaccta tgctaattgt atttatggga ttaattattg gtacttttat tttagcaatg
    30001 gttgttccta tgtttgatgc aattactaat ttttagagag aaaaataaat tttattagat
    30061 gaaacttttg aaaaggagag aatatttaat tgataaattt gataaataaa aaacgaaaag
    30121 gatttacact tgttgaaatg attgtagtag taactatttt aggcgttata tctagtatag
    30181 cattagttaa gtatagtaag gttcaagaaa gtgccaaatt aaatgcagac tatacgaatg
    30241 ctgctaatat agtaaccgca gctagcatgg caattaatga tgatgaaaag acaatagact
    30301 ctctaagtgt agagacattg aaggaaaagg gatacctaaa tactgttcca gttcctcaga
    30361 gtacatcagg taaattcgaa cttgtcataa atgatagcgg aacagatata agcgtaaata
    30421 taaattctaa gcaattttat ccaaaataat attttatatt gattgctgta agttttaaaa
    30481 ttatttttat ttaagaagga gatggctata attaaaaaaa ttctaaactt agaaataaat
    30541 gatgattata taaggcttgt atttttaaga aaaagtcata aaaaagtttt tatagataaa
    30601 tcaattataa aagagattaa ctttgatata aaaaatgata gtaattcgat tgagaagatt
    30661 aaatatatag aagatgtagt tagatttgta aaagaggaga ttggtaaatc aaaaatatta
    30721 tataaaaatt tatactttaa cattcaaatt caggatatag tcattagaaa tgttgaagtt
    30781 ctaaatacta agaaaaaaag agacatatta agcatgattg aatttgaaat aacacaatac
    30841 attccaataa acataaataa ctattcaata aaatataaag ttataaattc taaaaatgat
    30901 aaattgaata tacaagtaat tcttttccca aagagtatta ttcaattaat taagaacatt
    30961 tcagaaaatc taaatatgaa tccaaagact ataaatataa attttgatat attacaaaag
    31021 cttataaact taaatttaat agagaatttt tcagaagaag gggtatttat agaatgtaaa
    31081 aaaagtcagt taattataaa tataacaaaa gataaaaaaa taagagaaac atacttgcta
    31141 tcaaaagagg gaaaatcata tgagttcata aaaagattat taagggattt taagtatgtt
    31201 tattactatg gtatagaaaa ttgttttatt gaagaatact ttaaatatac agataaatct
    31261 attgaagtaa atccattaag attaaaagat aaagtaaaag tagaaaataa ttttgatgca
    31321 gatttagaag acaataggat aaattatata agtaatatag gaatgattat ttaagtgaaa
    31381 gtggataaaa cgataaattt tcttaatgga tttaaaaaaa ctaaaccatg taataaaatc
    31441 tataaaataa taatagtctt aattttaacg tgtattttat ttaaatcatt tatgtatgtg
    31501 aaatctataa atgaacttga agattatata agtcaaaata agctagtgga taaatcaaga
    31561 cacactttac caacaacaga taaaactaga gagaaatttt ctaaaataaa acttaatgaa
    31621 ataaaaaaaa tatatgaaac aattggaata aatattatta ctaaaatatc gatagataaa
    31681 aataagctag agattgaagg tgtgtgtagt gatttagatg ttttaaacaa tctaaggaaa
    31741 ataaagtaca taaaatatta ttacatagac agtattgtaa gagatggaga atattataga
    31801 tttagaataa aaagttagat gggtgattat ttttgagatt aaataataga gaaaaaaatc
    31861 tacttaaaat attgttaata ttagttatta tattggcaag tgatatagca gtaagttatt
    31921 tggaagaaaa cttaactagt ttgaagaatg aaaagcaaaa tataataaat aaaataaata
    31981 atcaagataa ttatcaaata aaggataata agcatataga tgataaatat atagaaagtg
    32041 ttgaatcaaa taaaaatgaa gaattaaaaa ataattttaa taactcattt ttagataaaa
    32101 aaacaaataa agatatagtg ttattagtag aaaatgaact gagagatatt gtgaatgtag
    32161 aatatattaa tcaagaaagt agtttagata atcacaataa aaaacaagtt aatttagaaa
    32221 taaaagttaa tggagaactt gcaaatttgt tgaaacttga aggtgtaatg aagaagttaa
    32281 gactaaataa taaacttgaa aagatagaaa ttaataaatt aaaagtcaat aattttgatg
    32341 ttcaaaatat tccaaatgaa tataaacaag aaaaagacaa tattgttgaa tgtaaaatga
    32401 cagttagagt catataacaa aaaagaatag ataaagtaaa aaactattat caattaataa
    32461 aattttatag aggaattagt tttacgataa ttcatttcta caagagggat tgttgatgat
    32521 tttatcgaaa tcctaattaa agttaatata ttgtaccaaa atataagtga atttaataga
    32581 atatttactt atactataga ttgattaata aaaaaatggt ataataacaa attgtacttt
    32641 aatttaataa taagggagtg gaagtcatat tgttagggag aaatgagcta tgcccttgtg
    32701 gaagtggcaa aaaatacaag aaatgttgtt taaataaaga tattgtttca gaaagagcat
    32761 gcagaaaaac tgaactttca caaaaacaat atacagattt atattcaaag ttatatgatt
    32821 attcaagaca ggataagttt aaagaagaat gtgaaaaagc taaagaaatg ttttatataa
    32881 tgcaaaatga tagtgtaaat gaaaaatttg aaagattttt taatacttat ttaatacaag
    32941 accacataat ggaaaataaa aaggttatga cagttggttt tcttgaagaa aatggtgcaa
    33001 acctaagtca atcagaagta tcaatattaa aaagtatgtt tgaatcatac gtaagtattt
    33061 atgaggtaaa agaagtttct gctggaaaaa tagtattaaa ggactgttta agtggaaatg
    33121 aactttgtac agaagatgta aaacttctga gaagttttaa aatcggaagt tgtatgatag
    33181 ctagaatagt tgatattgaa ggaactaaca tattgataga tataactata agtatatcaa
    33241 atgaggttaa agatataatt ttaaaggata ttatgaatct attcaatcaa tatcaagatg
    33301 tatacaaaga tatgaagtcg ttcttaattt atcatacaca tatactatac aagtatatac
    33361 aacagctttt agacccaagt atagctgaat atttaaagag agaaagagat aaaaacgata
    33421 caaaagttaa ttcagaaaat gaattagctg aagaagaatg taaagtttta gatactctta
    33481 aagaaaatgt agaaaaagaa aatatagatg catgtataga gttttggaat gaatataaga
    33541 aaaatcatga aaatataaaa ggagctgaaa atggttgggc agctgctgtt gaatactatg
    33601 ttaaaaaaga agcaggacaa cctataactc aagttcaaat atcaaagaaa tacgatataa
    33661 gctctagtac actaggaaag agatacaagg atttaaaaat atcttaatta attataaaaa
    33721 gctttaagtc atagataaag aatctatagt ataatatatg tataatgttt agaaagaggt
    33781 attaataatg agtcttagtt taggaaatgc aattgctgta tcaacgaact ttataaaatc
    33841 taacccagct gtacctgtgt acaatggaga agaaatatat gcagttattt atcatataga
    33901 aataggatat aataatggtg tatcacctga taccaaacaa tatataataa tagactataa
    33961 agagtttgat ttatctatgg ataaaaaaaa tgaactaata aatattgcta aagagtactg
    34021 taaatctaaa ggtattgtag aaaacgaaaa ccttgaaata aaccttttag acaatgaaga
    34081 agcagagaac ttcttagaaa aggtgtttaa taatatgaag gttataagag gtcttataac
    34141 taaaaaagga taaataaatg gactatatag gaatagaaaa tataacacct tatgaaaata
    34201 catatgaatt tagtgtatat gaatatgatg atgaaatcac cttaggtagt gaaaagttat
    34261 atgtatgtga attaagggtt gtattgatta aagttaattc tctgtatgtt gaaagattgc
    34321 ataaatcagt tgaagcaatg gtcttagtaa aaaacttgaa aaaagattta gataaaacac
    34381 ttgttgtaaa caaaataaag aattttgtgc tagatgagat ttgggtagaa aatctagtaa
    34441 aagagaatat agaagttata tttgtagaaa gctaggaata accctagctt ttttatatta
    34501 caatctaaga gaggaaaaca atatgttaag agtatctaat gtaaaacttg gaattgataa
    34561 agatatatct ttattaaaag atgttatact taagaagcta aaaataaaag aaaaaaactt
    34621 agtcaaatat agtatatata aagaatctat agatgctaga aaaaaaggaa aaatggaatt
    34681 tgtttattct gtagatgtag aagttaaaga tgaaaataaa atacttaact caaaaataaa
    34741 agatgtaaca aaaataaagg aaatcagata cgtaaatgta cctgtgggtg ataaaaaatt
    34801 aaagaataat cctttggtaa ttggtagtgg accagctggt ttgtttgcag gtctgctttt
    34861 agctcaaatg ggttatgaac caatcatact tgaaagaggt cttgatgtag acagtagaac
    34921 caaagatata agtgattttt ggacaactag aaaattaaaa aataattcaa acgttcaatt
    34981 tggagaaggt ggagcaggaa ctttttcgga tggtaaactt acaactagaa taaaagatat
    35041 acgatgtaga aaagtattag aagagttagt tcagtttggg gcaccagatg aaatattata
    35101 ctcacataag ccacatgttg gaacagatat attaaaaaat gtagttaaaa atataagaaa
    35161 tgaaataata agtttaggtg gtcaagttag atttaattca aaagtaacag atatagttgt
    35221 atcaaatgat tctatacaat ctgtaataat aaatgatact gaaaaaatag atacagatac
    35281 aattatatta gctgttggac atagtgcaag agatacttat gaaatgttgt attcaagagg
    35341 tataaaaata gttcaaaaac cttttgcaat aggagctaga gttgaacatc cacaagattt
    35401 aataaataaa gcacagtaca aggattttta taatcaccct aggttaggag ctgcagatta
    35461 tagacttata gagcatgttt caaatggaag aacagcatat actttttgta tgtgtccagg
    35521 aggtagtgtc atagcatctg catcaaatga ttttgaaata gttacaaatg gtatgagtga
    35581 acatgcaaga gataaaataa atgcaaatag tgcattttta gtaaatgtaa cgccagaaga
    35641 ttttaagagt gataatccac tagcaggtgt tcatttccag cagaagtatg aaaaattagc
    35701 ttttgaatta ggtggaaaaa attataatgc accagttcag cttgttggag attttataaa
    35761 caataagact tctttgaatt taggaagtgt tgagccatca tatagaccag gatatacact
    35821 tacaaattta agtgaatgtt tgcctagctt cgtaacagag actatgagag aagcgtttat
    35881 atctcttgat aaaaaattga atgggtttgc aatgtatgat gctgttttga cgggagtaga
    35941 aactaggtca tcatcaccaa taagaatagt gagagatgaa aatactttag aatcagtgag
    36001 tattaagaat ctatatccat gtggtgaagg tgctggatat gcaggtggta tagttacagc
    36061 agcagttgat ggtataaaat gtgcagaaaa aataatacaa aaatacacca ataatacaaa
    36121 aatttaacat aaacttaatg attttttaat atttaacatg aatttaacat tatcactcct
    36181 ataatttgat aaaatacaat aggttataaa atttttagat acagtaatct ctttacaagg
    36241 aggaaataat ttgaacatta taataagtct aatgggtgga ttaggtctgt tcttatatgg
    36301 tatgaacctt atgggagaag gtcttcaaaa atctgctggg acaaagctaa aaaagataat
    36361 aaaactactt actagtaacc tatttatggg agttttggta ggtacaggag ttacagcagt
    36421 aatacaaagt tcaagtgcta ctactgtaat ggttgttggt ttcgtaaatg caggaataat
    36481 gactttaaaa caggcaatag gagttataat gggtgctaat atagggacta ctgttacagc
    36541 ccaattggta tctttcgact taactggtat ggccccagta gcattaggtg taggtattat
    36601 actttattta tttggaaata agcctagaat aaaaaatata gccgaaatac ttataggttt
    36661 tggtatatta tttacaggta tggattttat gaagatggca gtggagccac taagagacta
    36721 tcaaggattt actgacttac ttgttacatt tggtagatat ccactacttg gattattatt
    36781 gggatttggg attacagcaa taatacaaag ttcaagtgca tctatgggta tgttggttgc
    36841 actggcagca gaaggtctag tgccactatc agcagcactg ccaattcttt atggccaaaa
    36901 tattggtaca tgtgtaactt cactgttatc aagtattggt gctaacaaaa atgcacgaag
    36961 agcagctatg atgcatctaa tcttcaatgt tttaggaacg gtgatattct taatattctt
    37021 gaataaacca gtagtaagca tggttacaag ttgggatcca agcaatgttg caagacaaat
    37081 agccaataca catacattgt ttaatataat atctgtattg atacttttac catttacaag
    37141 tcttattata aaactagcta taaagcttgt tcctgataga gcaggtgata tagatgaaga
    37201 tgaaactaaa actattaaat atatagatga tagaatgata gaaactcctt ctatagctct
    37261 tgcaaatacg ataaaagaag cacttcgtat gggtgagaag gcgaaggaaa gcctaaatgc
    37321 atctatggaa gctttagtag aacattcaac tgaaaaaata gataagacat atagacgaga
    37381 gagattaatc aatgatttac agaaagctat tttaaattat ttacttaaac tttcaaaagc
    37441 agctttagat gatgattcaa gagaagttgt ggatactttg tttaatacag tcaatgatat
    37501 agaaagaatt ggtgaccacg ctaaaaatat agctgaatta tcacaagttg caatagattc
    37561 aaatatttat ttctcagaag aaggacaatc tgaacttgat gttatgtata atagagttgt
    37621 ttcagcatat acttatgcat tagaatcaat gaggagcgat aatgttgatt tagcttgcaa
    37681 ggttataaaa attgaagaac aagttgatat aatggagaaa tcttgtagag ctaatcacat
    37741 gtatagattg aataataatc tatgtagtat agaaaatgga gttatttatt tagatgtaat
    37801 aagtaattta gagagaatat ctgaccatgc tgtcaatata gcacaacaag ttatagcgaa
    37861 gagattagga aatgattaaa aataattaat ttaaaataat ataaaattta aaatagagga
    37921 taaataaaag agaaacttta aatgatacgt ttagagtttc tttttttgta aatttatttg
    37981 actaaaattt ttaaatttat acatagttat agtatttaga agaatcgatt tcctgataat
    38041 aaatgatgag atatgtatga ttttgtggca aacttttaaa aaaaacacct atattttgtg
    38101 ttataatctc tttaaaacga atatgctgaa aagagggatt taaatgggaa aaataaattt
    38161 tgattatagt aaagctacag agtttttttg tcaaaacgaa atagatgtca tgcaaccata
    38221 tgtagatgtt gcgcacgaca tgttacataa taaaactggt ttaggaaata cttttttagg
    38281 atggatagac cttcctaaaa attatgataa agaagagttt gacagaataa aaaaatctgc
    38341 tgataagata aaatcagact cagatgttct tttggtaata ggtataggag gctcttattt
    38401 aggttcgaga gctgctatag atatggtaag tcattctttt aggaatggac ttaaaaaaga
    38461 gcaaagaaag gctccagaag tatattttgt agggcataat ataagctcaa catatattat
    38521 ggatttatta gatataattg aaggaaagga tatttctgta aatgtaatat ctaaatcagg
    38581 aactactaca gaaccagctc tggcttttag aatatttaaa gattacttag agaaaaagta
    38641 tggtaaggaa gaagcaagaa agagaattta tgcaacaaca gatgcaagta aaggtgcact
    38701 tagacagtta gctacagaag aaggatatga gacttttgta ataccagatg atgtaggtgg
    38761 tcgtttttct gtattgacag cagttggatt acttcctatt gctgctgctg gacttgatat
    38821 tgatgctatg atgaaaggcg caaatgatgc tagagaagca tttcaaaatc ctgacttaaa
    38881 aagtaatgat agttatagat atgctgttgc tagaacaatt ttacatagaa aaggaaaaga
    38941 tgtagagtta ttagtgaact atgaacctca actacattat gtaagtgagt ggtggaaaca
    39001 gctttatgga gaaagtgaag gaaaagaaaa taaaggttta ttccctgctt ctgtagattt
    39061 ctcaacagat ttacattcta tgggtcaata catacaagat ggaaaaaggc ttttatttga
    39121 gacagtactt aatgttgaaa actgtaagag aaatataact ataagttcag aggaagtaga
    39181 cttagatggt ttaaattatt tagcaggtaa gactgtagat tttgtaaatc ataaagcttt
    39241 tgaaggaact ctattggctc atacagatgg aaaagtacct aatttagtaa taaatatacc
    39301 tcaactagat gagtataatt ttggatattt agtttatttc tttgagaagg cttgtggaat
    39361 aagtggatat ttattgggag ttaatccatt tgaccaacca ggagtagaag cttacaagaa
    39421 aaatatgttt gctttactag gcaaaccagg ttatgaaaaa gaaaaggaag agctagaaaa
    39481 aagacttaaa taattttaaa tagttaaggt ttaattaaga ttaaaataat ataatgaaat
    39541 catcaaaaag gagtttactc aaaatagatg atttcatttt ttttatgaaa aattgggaaa
    39601 aatatatttt gataatttat attatattaa gatagggagt ggtatgagat gtcaagaaga
    39661 aagaaaggga taagtttagt aatattagtt gctataataa gttcaatact tagtagtttt
    39721 ctaacaataa ttttagttaa ggacaattta gtaagcaaat ctacaggaag ttctacgccg
    39781 atagttgtaa atgatgatgg taagagtcaa aatatttatc aagcagttgc agaaaaagct
    39841 acgccatctg ttgtaggtat tacaacaact agtgttgata ctagtaatat gtttgcaata
    39901 ccaactgaaa cacaaggtgt aggaactgga atcatagttg attcaaatgg atatatactt
    39961 actaattctc atgttatatc agatggtcaa gctacaagtg taaatgtatt attcaatgat
    40021 ggttcaacaa cttcaggtaa agtagtatgg tttgaccaac aacttgattt agctatagtt
    40081 aaggttgata aaactggact aacaccagca gaatttgctg atagtgacaa agtaaaagtt
    40141 ggagatatat caatagcaat aggtaatcct cttggattag attttcaaaa aacagttact
    40201 caagggataa taagtggatt agatagaact atacaaacag aaaaaactaa tatgactggt
    40261 ttattacaaa ctgatgcaag tataaatgca ggaaatagtg gaggaccatt gttaaatcaa
    40321 aaaggtcaag taattggtat aaacacagca aaagcttctc aagcagaagg attaggattt
    40381 gcaataccaa tcaatacagc taagagtata gttgaagaag taatcaaaaa tggaaaatat
    40441 gaaaaagtaa ctttaggcat aaaaggtaca gatgtatcaa attatgaagc agcaacaggt
    40501 acaaaattaa gtactgataa aggtgtttat gttgcagaag taatatctgg ttcatcagca
    40561 gaaaaagctg gagtaaaggt aggggatatt ataactaaag taggagatac agatataaca
    40621 ggtatgaatg atttaaataa aaagttgtat actttctcaa aaggtgctag tacaaaaata
    40681 acagtaaata gaggcggaaa agcagtaaca ataaatgtga atttctaaat atgaccaaaa
    40741 agatagagac tacatggtaa agtgtagtct ctatttttat ttaattttta tagtatatac
    40801 atctaaatta attaaaatga tgtattgttt atagtttatt gctatatttt cttataaaaa
    40861 taaatttaat aaatatttaa atttaattta caaaaacaat ataaatatca taataaaata
    40921 aaatttttta atattactaa aaatatatag acaaaataat aacaaatata gtattatgta
    40981 attgtagaaa tgcttttcat aggtatattc tatgaagatg aattgcataa aaatgaaaaa
    41041 atggaatgga tattatttag gggtgaaaaa tcatgaatcc attagttata aacttacaaa
    41101 aatgtagcat acatgatgga ccagggataa gaagtacagt attttttaaa gggtgtccac
    41161 ttgaatgtgt ttggtgtcat aatccagaga gtcaaacata tacaaaacaa gttttgtata
    41221 atgaagaaag atgttcaaaa tgtgaagcat gtataaatat atgccctcat aaggcaattt
    41281 acaaaggtga aacaaaaata tgcttagacc aagataagtg tgagttttgt gaaacttgct
    41341 tagactattg tgtaaacaat gcaagagaga ttgttggtca agagtattct gtaagagatt
    41401 tggttaaaga gatagagaag gatagaattt tctatgaaga atcaggtggt ggagtaactc
    41461 tatcaggtgg agaagtaatg gctcaagata tggacttcat ttgtggagta ataaacatgt
    41521 gcaaatcaaa gggaatccat gtagcaattg atacatgtgg ctatgcaaag tcagaaaatt
    41581 atgaaagagt tgctaaatgt gcagatttgt ttttatatga tattaagctt attgatgaag
    41641 ataagcacat aaaatttaca ggaaaatcaa atgacttaat actgaaaaat gttaagattt
    41701 taagtgaatt aggggctaac ataaatataa gaataccatt aattgtagga gtaaatgtag
    41761 atgatgaaaa tttagaggtt aaaaaaatga tagagttttt aaagcctttg aatatacaag
    41821 cagtaagtct tcttccatat cataatattg gtaaacacaa gtatgataaa atttataaaa
    41881 agtatgaagg agaagaacta caaagaccat cagaagaaaa attagaggaa ataaaaagac
    41941 tgtttgaagc aagtaatttc aatactaaga ttggagggta ataaaatggc aagaggaact
    42001 tttgagagaa ctaaaaaatt aagagaagaa agtattaatg cagaaccaca catatctatt
    42061 gaaagagcag tacttatgac agaagcttat aaaaaatatg agggaagtgt agagattcct
    42121 gtacttcgtg ctttatcatt taagcattat attgagaata gaactcttag cataaatgat
    42181 ggagaattaa tagtaggtga aaaaggtgat tctcctaatg gagcaccaac atatccagaa
    42241 atttgttgtc atacaatgga agatttagaa gtaatgcaca atagagatat aataaatttt
    42301 agcgtatcag aagaagctag aaaaatacat aaagaagaaa taattccttt ttggaaaaag
    42361 agacaaacaa gagataagat aataaatgca atgacacctg agtggttagc agcatatgaa
    42421 gcaggtatgt ttacagagtt tatggaacaa agagccccag gacatacagt ttgtggagat
    42481 acaatatata aaaaaggatt tttagattta aagaaagaca tagaagcaag attaaaagag
    42541 ctagattttc ttaatgattt agatgcatat aataaaaaag cagatttaga agctatggca
    42601 atagcttgtg atgcaatggt tatattaggt aaaagatatg ctgagaaagc aagacaaatg
    42661 gcagaagaag aaacagatga agctaagaaa caagatttat tactaattgc tgaaacttgt
    42721 gatgttgtac cagctcacaa accagaaact tatcatcaag ctatacaaat gtattggttt
    42781 gttcatatag gggttactac tgaacttaat atatgggatg cttttactcc aggaagactt
    42841 gaccaacatc taaatccttt ctatgaaaga gatgtagaaa atggaatact agatagagat
    42901 agagcacaag aattacttga atgtttatgg gttaaattta acaatcagcc agcaccacca
    42961 aaagttggta taacattaaa agaaagtagc acatatacag attttgcaaa tataaacact
    43021 ggtggaataa atccagatgg tcaagatggt gttaatgaag ttagttatat aatacttgat
    43081 gttatggatg aaatgaaatt gatacaacct agttcaaatg ttcaaataag taaaaagact
    43141 cctcaaaaat tcttaaagag agcttgtgaa atatcaagaa aaggatgggg tcaaccagca
    43201 ttttataata ctgaagcaat agttcaagag cttatggaag ctggaaaaac tatagaagat
    43261 gcaagacttg gtggaaccag tggttgtgtt gaaactggat gttttggtaa agaagcatat
    43321 gttctaactg gatatatgaa cattccaaaa atacttgaat taacattaaa taatggatat
    43381 gacccaatta gtaaaaaaca aataggtatt gaaactggag accctagaaa tttccaatct
    43441 tatgaggaac tatttgaagc atttaaaaag caattacatt atatgattga cataaaaata
    43501 gaaggaaatg ctgtgataga aaatatatgt gcaaaacaca tgccttgtcc acttatgtct
    43561 acaatagttg atgattgtat agaaaaaggc aaggattacc aaagaggtgg agcaagatac
    43621 aacactagat atatacaagg tgttggtata ggaactataa cagatagttt aacagcaata
    43681 aaatataatg tatttgataa gaaaaaattc gatatggata cattgcttaa agcacttgat
    43741 gctaattttg aaggatatga agctatactt aatttagttt caaataagac tcctaaatat
    43801 ggaaatgatg atgattatgc tgatgaaata atgcaagaga tattcaatgc atattacaat
    43861 gaggtaactg gtagaccaac tgtttgtggt ggagaataca gagtagatat gttaccaaca
    43921 acttgtcata tatactttgg agaaattatg ggagcaagtc caaatggtag actttgtgca
    43981 aaaccagttt cagagggaat ttcacctgaa aaaggtggag atactaatgg acctacagca
    44041 gttataaaat cttgtgctaa gatggaccac ataaaaactg gtggaacatt attaaatcaa
    44101 agatttgcac catcagtagt tcaaggagaa aaagggttag ataatatggc taatctagta
    44161 agagcatact ttaatatgga tggtcatcat atacaattta atgtatttga taaaaatgta
    44221 ctgttagagg ctcaaaagaa tcctcaggat tataaagact taatagttag agttgcagga
    44281 tatagtgacc atttcaataa tttaagtaga acactacaag atgagataat aggaagaact
    44341 gagcaaacat tctaggtttg cttgtaaata aaacttctta ctatataaaa tcgtaactga
    44401 tataataaag tataaatggt ttgattccat ttttaaaatt ttagattaat tatgagctaa
    44461 ctttctaaat aggaagttag ctcgttaagt ttaatgaaaa aatcgttaaa tttatattta
    44521 gtaaatcata cacatattag taagtaatac atacaaaaga ataatttatt atagttataa
    44581 taaggttata ttttataaaa ataagataat tttaagcagt taaaataaag tcaatttagc
    44641 tactttaaaa taaaactaat agaaaaaagg agatttgata tgaaaacttt aggatttatt
    44701 ggttcaggga atatgggaag tgcaatgata ggtggcatag tacagtcagg attagtaaag
    44761 gcagaagata taactgtatc agatttaagc caagttgcct tagataaagt aaaagaagaa
    44821 tttggagtaa atactacaac tgattcaaag gtagctgtta caaattctga tgtggtaata
    44881 gtagcactta aacctaatat atgcgaaaag gctttaactc cacttaaaga attaatagat
    44941 gcaaataaaa taatagtatc tatagcagca ggtaaaacta tagaaagtct ggaaagtttt
    45001 ataggttcag ataaaaaaat agtaagagta atgcctaata ctccagccct tgttggcgaa
    45061 ggaatgtcag ctctttgtaa aaatagtaat gtaacagatg aagagttaaa tatgattaag
    45121 gctctgtttg aatcttttgg tgaggcagaa atagtatcag aatatttaat ggatacagtt
    45181 acaggtatta gtggttcttc tcctgcatat gtatttatgt ttatagaagc tatggcagat
    45241 gcagcagtat tagctggaat gccaagacaa caagcttata aatttgcatc tcaagcagta
    45301 atggggtcag ctaagatggt tcttgaaact ggaaaacatc caggtgaatt aaaagatatg
    45361 gtttgttctc cagcaggaac tactatagaa gctgttaagg tattagaaga agaaggcttt
    45421 agagcagcag ttataaaatc tattgttgct tgtatagata agtctaaaga tatgagtaaa
    45481 taacagatgt aattaagttt actatatggt ttcttgaatt gtttttttag tgcttattta
    45541 tatctataca taaatgtatt tggtataagt aaaataagag taatttacta taaaaaggaa
    45601 tttaatgatt gagtgagaat ttattactta aatattaata attaaataga tatattttta
    45661 actatatttg agatatatca ttgtgaaaaa ataaaattta taagtattat tgtgaggtta
    45721 taagtagatt tatttaaaaa taaatttatt tatagccttt ttaaatttga aataatattc
    45781 ataaggtaat aaaagttaca aatattttct tcgctaataa gttttaaaat acctataatg
    45841 ttttacttt
//
LOCUS       DAGQVA010000024        45678 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.024, whole genome shotgun sequence.
ACCESSION   DAGQVA010000024 DAGQVA010000000
VERSION     DAGQVA010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45678
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.024"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..2245
                     /locus_tag="MIV85_001510"
     CDS             <1..2245
                     /locus_tag="MIV85_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960856.1"
                     /translation="DDRVYQAGTSITIGSSKIKDSGISVLVKEYDKTGLSNYPKLMKL
                     KSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLLNDTIPPYNYTANFKLSG
                     ILEDDYTGYVSGIVNGIVGKGTSENLLPKRYTLSSLDFKIKQQEKFQEIVNQLAKKIN
                     LSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLFVALLVLLASGLVIYNIL
                     KISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIPIGAVIGIISSKGITGMV
                     TNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLIFSLISALPSAIYASHVS
                     PKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRTIITILSLFMSITVFVAL
                     SEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKMKNVNRTSFIKYSEYKQG
                     EIDTDINFENSGEMLKIIGIDEQTLKDLMPSITNSILEDFKNGSICFIKNPIAISTPG
                     VKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWINGVDVIVYDSVYNTLTNKN
                     KFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESDKQLKESFKQIEFLAWAV
                     ILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLYKMFLWEGVYYGIFAAIF
                     GSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLACIIATLIPLRKVKKMNII
                     DCIDINL"
     gene            complement(2485..3909)
                     /locus_tag="MIV85_001511"
     CDS             complement(2485..3909)
                     /locus_tag="MIV85_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960857.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(3928..4620)
                     /locus_tag="MIV85_001512"
     CDS             complement(3928..4620)
                     /locus_tag="MIV85_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960858.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(4672..5451)
                     /locus_tag="MIV85_001513"
     CDS             complement(4672..5451)
                     /locus_tag="MIV85_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBY2960859.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(5448..6218)
                     /locus_tag="MIV85_001514"
     CDS             complement(5448..6218)
                     /locus_tag="MIV85_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBY2960860.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(6215..6919)
                     /locus_tag="MIV85_001515"
     CDS             complement(6215..6919)
                     /locus_tag="MIV85_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBY2960861.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(7174..7686)
                     /locus_tag="MIV85_001516"
     CDS             complement(7174..7686)
                     /locus_tag="MIV85_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960862.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSDCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            8012..8269
                     /locus_tag="MIV85_001517"
     CDS             8012..8269
                     /locus_tag="MIV85_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960863.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDCEQAESLINSKLR"
     gene            8412..9038
                     /locus_tag="MIV85_001518"
     CDS             8412..9038
                     /locus_tag="MIV85_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBY2960864.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(9285..10064)
                     /locus_tag="MIV85_001519"
     CDS             complement(9285..10064)
                     /locus_tag="MIV85_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBY2960865.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(10132..10593)
                     /locus_tag="MIV85_001520"
     CDS             complement(10132..10593)
                     /locus_tag="MIV85_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2960866.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(10569..11246)
                     /locus_tag="MIV85_001521"
     CDS             complement(10569..11246)
                     /locus_tag="MIV85_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2960867.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            11479..11865
                     /locus_tag="MIV85_001522"
     CDS             11479..11865
                     /locus_tag="MIV85_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2960868.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            11868..13667
                     /locus_tag="MIV85_001523"
     CDS             11868..13667
                     /locus_tag="MIV85_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBY2960869.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(14022..15896)
                     /locus_tag="MIV85_001524"
     CDS             complement(14022..15896)
                     /locus_tag="MIV85_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2960870.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLASIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(15901..17565)
                     /locus_tag="MIV85_001525"
     CDS             complement(15901..17565)
                     /locus_tag="MIV85_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBY2960871.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(17579..18400)
                     /locus_tag="MIV85_001526"
     CDS             complement(17579..18400)
                     /locus_tag="MIV85_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBY2960872.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKNREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(18499..19263)
                     /locus_tag="MIV85_001527"
     CDS             complement(18499..19263)
                     /locus_tag="MIV85_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2960873.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(19260..20009)
                     /locus_tag="MIV85_001528"
     CDS             complement(19260..20009)
                     /locus_tag="MIV85_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2960874.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(20513..21118)
                     /locus_tag="MIV85_001529"
     CDS             complement(20513..21118)
                     /locus_tag="MIV85_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2960875.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            21297..21935
                     /locus_tag="MIV85_001530"
     CDS             21297..21935
                     /locus_tag="MIV85_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2960876.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            22067..22729
                     /locus_tag="MIV85_001531"
     CDS             22067..22729
                     /locus_tag="MIV85_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960877.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            22729..23910
                     /locus_tag="MIV85_001532"
     CDS             22729..23910
                     /locus_tag="MIV85_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2960878.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(24091..26751)
                     /locus_tag="MIV85_001533"
     CDS             complement(24091..26751)
                     /locus_tag="MIV85_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960879.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(26748..27431)
                     /locus_tag="MIV85_001534"
     CDS             complement(26748..27431)
                     /locus_tag="MIV85_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960880.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(27775..28728)
                     /gene="blaCDD"
                     /locus_tag="MIV85_001535"
     CDS             complement(27775..28728)
                     /gene="blaCDD"
                     /locus_tag="MIV85_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBY2960881.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(29269..31383)
                     /locus_tag="MIV85_001536"
     CDS             complement(29269..31383)
                     /locus_tag="MIV85_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBY2960882.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
     gene            complement(31467..32303)
                     /locus_tag="MIV85_001537"
     CDS             complement(31467..32303)
                     /locus_tag="MIV85_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2960883.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(32887..33249)
                     /locus_tag="MIV85_001538"
     CDS             complement(32887..33249)
                     /locus_tag="MIV85_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBY2960884.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(33483..33947)
                     /locus_tag="MIV85_001539"
     CDS             complement(33483..33947)
                     /locus_tag="MIV85_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBY2960885.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLVKLDVEVGFPVATYIDGKNEILQKIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(34376..35797)
                     /gene="nhaC"
                     /locus_tag="MIV85_001540"
     CDS             complement(34376..35797)
                     /gene="nhaC"
                     /locus_tag="MIV85_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBY2960886.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(35827..36891)
                     /locus_tag="MIV85_001541"
     CDS             complement(35827..36891)
                     /locus_tag="MIV85_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBY2960887.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(36876..38285)
                     /locus_tag="MIV85_001542"
     CDS             complement(36876..38285)
                     /locus_tag="MIV85_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBY2960888.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIKYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(38285..40489)
                     /locus_tag="MIV85_001543"
     CDS             complement(38285..40489)
                     /locus_tag="MIV85_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBY2960889.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(40483..40857)
                     /locus_tag="MIV85_001544"
     CDS             complement(40483..40857)
                     /locus_tag="MIV85_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBY2960890.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(40935..42365)
                     /locus_tag="MIV85_001545"
     CDS             complement(40935..42365)
                     /locus_tag="MIV85_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBY2960891.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(42358..42666)
                     /locus_tag="MIV85_001546"
     CDS             complement(42358..42666)
                     /locus_tag="MIV85_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBY2960892.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(42787..43854)
                     /locus_tag="MIV85_001547"
     CDS             complement(42787..43854)
                     /locus_tag="MIV85_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBY2960893.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKINFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(44110..45483)
                     /locus_tag="MIV85_001548"
     CDS             complement(44110..45483)
                     /locus_tag="MIV85_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2960894.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYTLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
BASE COUNT        15324 a         7860 c         5321 g        17173 t
ORIGIN      
        1 agatgataga gtttatcaag ctggtacttc aataactatt ggcagtagta aaataaagga
       61 ttctggtatc tctgtacttg taaaagagta tgataaaaca ggactttcta actacccaaa
      121 attaatgaaa ttaaaatctg gacatttgcc taaagataaa aacgaaatag ccttagatga
      181 aaacacacta aagcttatgg gtataaaacc aagactagga gtgactatac ctatgaattt
      241 agatatttca cttttaaatg ataccatacc accatataat tacacagcta actttaaatt
      301 gagtggcatt ttagaggatg attatacagg atatgtaagt ggtatagtaa atggtattgt
      361 aggtaaaggt acatcagaaa atctattacc taagagatat actttatcct ctttggattt
      421 taaaataaaa cagcaagaaa agtttcaaga aatagtaaat caattagcta aaaaaataaa
      481 tctttctcac aattcaattc aatataattg gatttactta aatgctctta agatacagtt
      541 tgaaaaagat gaaaatagtt ctaatagtga tggtatatct atgattatat tggtatcttt
      601 atttgttgcc ttattggttt tactggcttc tggacttgta atctataata ttttaaaaat
      661 ctctgttaca aagaaaatta aagagtatgg atgtttaaga gcaataggag ctgaaccaaa
      721 ccagatatat aagatagtta ttttacaaat cttaatttta tgtactgttg ccatacctat
      781 tggagctgta attggaatta tatcttcgaa aggcataact ggaatggtca ctaatatctt
      841 aaatccagat atacttctag caaatgataa taaagaaatt actgagctta tacataaaaa
      901 tacaacagca tatatgttcc cattagtatt aagcactaat gtatctttga ttttttcact
      961 tatttcagca ttaccatcag caatatatgc ttcacatgtc tctcccaaaa ttgctatggc
     1021 tggtagtact accaaaatca aaagaaaaat taaaagagaa aaaacaataa aaaactttga
     1081 aagacatcta gcatggctaa acttaaaaag aaataaagga agaactataa taactatact
     1141 atcattattt atgagtataa cagtattcgt tgcactgagt gagttctcta atgtattaga
     1201 tgtatctagg tcagtaagta atttaaaaga aggagatttt tccttaacaa atgaaatatc
     1261 tggttttgat aaatcaacac tagataaaat agctaaaatg aaaaacgtca atcgcacttc
     1321 ctttataaag tactctgaat acaaacaggg tgaaatagat acagatataa attttgaaaa
     1381 tagtggtgag atgttaaaaa tcattggaat tgatgagcaa actttaaaag acttaatgcc
     1441 ttctattaca aattctatac tagaagactt taaaaatggt tctatctgtt ttataaaaaa
     1501 tccgattgct atttctacac caggtgtaaa aactagatat acaaatttaa aacctaaaga
     1561 tagtatcaca atcaacaaaa aacaactaga tatatatagt acagtagata aaatgttctt
     1621 tttacaaggc aatggctgga taaatggtgt tgatgttatt gtatatgatt ctgtttataa
     1681 cactttgaca aataaaaaca agttcaacca gataaatatt tatgctaaag ataaatcaaa
     1741 attagaacaa ataagattgt ctattgaaca gatttgtgaa aataatcctg gctctcattg
     1801 gatatcatat attgaatcag ataaacaact taaagagagt tttaaacaaa tagaatttct
     1861 agcatgggca gttatattat ttgtgggatt gattggtact ttaaacatca ttaacacaac
     1921 tcatacaaat ataaatacta ggactaatga gattggagtt aaaagagcta ttggtatgag
     1981 taataggagc ttatataaaa tgtttttatg ggaaggtgtt tattatggaa tttttgctgc
     2041 tatatttggt tcaattgctg ggtatgccag tgctattatc ataaacatgg caactataga
     2101 aaagcttgat ttcactaata taccaattac ttcaatttta caagctacta ttatttctgt
     2161 acttgcatgt attatagcta ctcttattcc gttaagaaaa gttaaaaaga tgaatataat
     2221 tgactgtata gatatcaatt tataactatt ttacagataa taatataaat taaattatca
     2281 atgactgtct ctattttctt tcaaatctaa ctaataaatc tttttaacta taatataagc
     2341 tttaaaaaag gcctgtctca aaatagagat aagccttttt tcattgtcga aataatgaaa
     2401 atatatttaa cttcacaaaa aaagagtgcc tcacgaatta aaaatttcgc tttgagacac
     2461 tctcctttaa tttaaaatat atagttaaat gctatgccaa aatttcacac atgctccacc
     2521 tgattttgaa ttttctattt taacagaacc tccaagctgt tccactaatt gtttgacaat
     2581 gtaaagccca agaccagaat gtccaccttt tgtctgccta gcttcatctc ctcgataaaa
     2641 tttatcaaga gcctttttta aatctttaga gctaaaccct ctaccagaat cacaaatctc
     2701 ataagaaata caattttttt catcctttac agtaatacta atattaccac ctgatggagt
     2761 gtattgcaga ctgttggata tgatattatc aaaaattcgt gtcaacctat caacgtcgat
     2821 ttgaattggg gattgtatat tcccctgcat tttcaatata agttcaactt ccttttgatg
     2881 agcctgtaat tcatagtctt gcaccttttg cctcaaaaat tcaggtaaat ttataggaac
     2941 aagatttaat tgtatatttg acttttctaa gtcagacgta tattgcatct tttggacaag
     3001 agcagcactt ttttctgtat tttctcttat cactgtaaga tacctatgaa gtttttcatt
     3061 gtcatctgta ttattaccaa taagtgcatc tgtatatccc aaaataatag aaagaggaga
     3121 ttttaaatca tgtgctagag cttccaccat ttcaacacgt tcctgctcca tcttccactg
     3181 tgcagataaa gagcctttta attcgtcttt catttcagaa aaggcactac aaagtttacc
     3241 gagttcatta tctgaataat agtcgatttc aaaatcaagg tccttttctt ttatcttctt
     3301 ggacgcatca atcaatagat gtaatggttg attgatattc tttacaaagc gcttagaaag
     3361 ccatctagta aaacccacga tatatagaaa tggagaaaac aaagccatta taataactgc
     3421 aaatacaaat ctccctctaa tatttgcaaa ggtgattttc acttggtaga atagaataac
     3481 agcaccctca atctttccat tatccccttt gattggaaca gtatggatat aaccaccttt
     3541 acgaacagtt ttattgataa aattattaaa taattcttct tttgttttaa atagtttttt
     3601 ggggttagta ccatataaaa tattgccatt attatccaca acttgatata gcatatcatc
     3661 cccacgaatc gttcttttta aaccttcttc attcgattgt gataacaaag ctatgttttt
     3721 ttcattgatg tatttttcaa ttctaggaac ttgtcgctca taatagtttg gtggatagat
     3781 atccttattt aaggaatgaa tatacaaata gagagcaaat acataagtaa tcactgtggc
     3841 aactatactg gctattataa taaaaataaa agtatgtcta aattgggtaa taagggattg
     3901 atttttcatt taataacctc tctctcttta cattttattc cacttatacc caatacccca
     3961 aactgtggaa atatattctt tttctggtgt cacagcagaa aacttagctc gtattttttt
     4021 tactcgttca acaacagttg aggaatcacc ttcagaatca cacccccata ctttttcata
     4081 gatttgttct cttgagaaaa cttgtcctgc atggagtgct agtaattcaa caatatcata
     4141 ctctattttt gttaaatcaa tattcttacc atcaatttta attgcacgtt ccttcatata
     4201 taagcataac ttcccaaaat acaaagtaga tctcttgttc tcttcattga tatactgtga
     4261 acgcttttcc ctacgcagat tagcttcaat ccttgccata agttcacgca gtccaaatgg
     4321 ctttgttaca taatcatccc ctccaaaggt caaccctttg attttgtcgg tttctgattg
     4381 ctttgcactt aaaaatataa ttgggcataa aacatcatct ctaattgcct gacatacctc
     4441 aaatccattc attttaggca tcataatatc cagtataata aggtcaggct cctgttttga
     4501 taactctata cctgcctgac catcataagc tatcaacact tcatgtcctt ttgccttcaa
     4561 ttcatcctca agtagcatta ctaggtccat ttcatcatca ataatcaata ttttactcaa
     4621 tataacacca cctttctctt atgggaaggt cagtattaaa acaatattcg tctactcata
     4681 acttttcctt ccctcccaca ttttaaacca aataacgcct cctatcaaga atataatcaa
     4741 acctattgct actactataa gctctatact agctgtttgc atcactttag agtaaaatgc
     4801 ctcagttgaa atagttccag cttctttaat aaaataaatt cctggaagca tacctagttt
     4861 tactggccat gtccatggaa caaatgccca tactttttca ccaacgctag ttaatccaag
     4921 tattgctgcc atcaaaattc caccaatact aataccaata gatgcaccca taccccatgc
     4981 aaaactcacc caaagatgaa tagctaatag tggaagtgtc ccaatcacca caagtcctgc
     5041 tgctgacagg aataaccata ttgttgctcc agatggcact gcaatactca ttcctatgca
     5101 aagtatcaac gtagcaataa atgtgcatat agttaggcaa aacagaagaa aaagaaattt
     5161 tcccagatat aatctgacac gagaaatacc tacacataaa aaaccattaa aatttccagc
     5221 aagctcttcc tcctgcacta taaatcctgc taaaatacct actccaatag gaatgatgaa
     5281 tacagtccat actgtaaaaa atccttcaaa agcaaattct tgtgtacttc cagatttagt
     5341 tgtgagataa aaaaccacac ataatgaaaa aataataggc atacaaagag taagccactg
     5401 gacagctgtc ctctttgctc gaagccattc tgatgataat agttttatca tttgtcatcc
     5461 ctcctattga accaagctgc agtaagtgct gttaatacta taaacacaac caaagaaaca
     5521 acaatcccaa taggaatcac tgaagtattc aaaagtgggt ctccagcttc taatatagta
     5581 ccgttaggat gtatgttgat gattgggcat accattctaa ctgcccaact ccaaggtact
     5641 gcaatccaaa atggttttgt cgcagcaaga acaccaaata tcatacctaa agctccaact
     5701 cccatactta ggaacatacc tttccatgta gctagccata gctgaagtgg aagtatagca
     5761 agagaaacaa cccagcatac aatacttgcc cctataatct gtccaaaagg aactggacca
     5821 gctttcaata ttaaaccagt tataattgtt acgactatta aaactagcgt tgaaataaaa
     5881 ctgtagactg ccatagctat aactttatta atccaaagtg tcataggaga cacattgtgt
     5941 gtacgtaaag cacgataatt tccagctttt ttttcctgga aagctaccaa agtagcgaac
     6001 aatgcaaatc caataggcag aaataaaaat gaccaccagt taaaaattaa tgctaaaaga
     6061 ttttgccacg cccaagaagt tgtttgagat aatggatttt gcatgagtgt tgattgcatt
     6121 ataaatgcat atgctgcaaa agacactggg aaaaaaacaa taagtttacc cataaatgtt
     6181 cttttatact ttaaaagttc tgattgtaaa gcattcatct gttttgtcct cctttaagaa
     6241 taacatctgt aaaaaattct tctagatttt cattagggtc aggcattcct tgaaataata
     6301 gtcgtcctcc atttataatt cctatattat ctacaacttg agcaacctct gatagaatat
     6361 ggctagaaag aattacagtt ataccttttt tgggaaaaga agcaatcaat tcacgcaatt
     6421 cttgaatgcc aaaggggtca agaccattgg ttggttcatc tagtattaac aactctgggt
     6481 cactcaaaag tgcaatagct attcctaacc tttgtttcat acccatagaa aattgtgaag
     6541 ctctcttttt acctgtattt ttcaaattta ctatttccaa cacttcataa attttatctt
     6601 taggtattcc caatattttt gtatgtacta acaaattttc ctctgctgta aggtttccat
     6661 acaatgcagg ggattctatt aaagaaccta tttttgcaag agattctcgt ttccaaggct
     6721 ttctatcaaa aataatacga ccatttgttg ggcgaagaag accaacaagc attttaagtg
     6781 ttgtggactt tcctgctcca tttggtccta aaagtccata tatactattt cgttcaattt
     6841 gtagagaaac attgttaact gccatttgtt ctccatatct ttttgataag ttttttgttt
     6901 caagaattaa atctttcata ttaatttctc ccttcttgta ataccttaaa tctgttacta
     6961 agagaatact aacatgaaaa aataacaatt ctataacacc tactaatttt aataaaattt
     7021 aaaataaaaa atagagttac caattttatt ttggcaactc tatttaagtt tatgttttac
     7081 agttatatta gatttaaact tagtttcatt atcacactaa cttcaaattt actctataat
     7141 ctttaaatca aacactaatt tattaatcaa acactaatct attaatttat atttctttag
     7201 acatctaata tagtttgcta ctaaataata attatttata tcatatttat ctaatccttt
     7261 aaaagaagtt atttcatcat taagctcatc actaccttct acaaaaacac aacctgtttc
     7321 aaattccata cctacaataa tcttacagtc actataaatt tcctcttgag tatcgtacaa
     7381 tttttttgca tttccttcat ttggaattgt aaatacaata ggttttaatt ctttatcact
     7441 ggaaatcttt tgtgaaaaag gcttgtttaa cttaatatta ttgataacta catgtttaaa
     7501 ttcctctgaa gtttcttcta ctattacata ttttcgcttt aaaaactcta ttatttctaa
     7561 aacagactta gaatttactt ttaaaatact tttatatttt tcatataaag atttccactg
     7621 ttcaattttt tcctgtggta tttcttggat atgtgtactt attttttctt gagatatttt
     7681 tttcaattaa actctccttt caatacttaa atatccttat gaatctcaca tgactaaagt
     7741 tacaaggttt ctacttaata gaattttgca tacttaaata tgtcttatta attctctaca
     7801 ggatatctcc gtagttccta cgattcttac ataagttact tattttaaat tgttattagt
     7861 tatattctaa aaattattta ttttatcact aatataatac tcttaaaaac tttacaaatc
     7921 aatttaaatt tgctaccttt tatttataac aacttatagt acatttctcc tatgcttttc
     7981 aatatattac ttttaaaagg aggttttcat tatgatttta aatagagctg agcttttccg
     8041 aggatattct ttaaatagat ttaacgagat atgcaatata ttatcagtaa ataaaattaa
     8101 atataagtat aaagtgaaaa ataatgctta ctctaaaaaa ccttttttta atgaaataac
     8161 acttggcaat ttaggccaaa aggaagattt ctcttatgag tacttaattt atgttcataa
     8221 agacgattgt gaacaggcag agtctctaat aaattctaag ttgcgataga ttatctataa
     8281 aacatgacat tctgttgtca tgttttatat gttattatac tttcaaatat gctactatat
     8341 tttcaaaatt gtgtgcttta aaactagctt tttttagtaa tttaaagctt aaaactaagg
     8401 agactcgtta tatgaaaata aatataaaat caaagttaag tgaatttatt aaacagaaca
     8461 atctttttga tgacagcaga ataatatcct atcttcctaa tataacaata gaaacagaca
     8521 aaataaaaac tataatgatt aatgaggttg tcccaactaa caccaatgac gatttttata
     8581 gtgtagataa agatgctgat tatttaaaaa ctactattcc tttatttgac agtgcaggaa
     8641 taaaagtatc taacataaat gatatcctag atatgggtat ctatataact aatgcagtaa
     8701 aacttcctaa atcagaatat acaataactc gtgatacaat taaattacat atgcctattt
     8761 tagaagaaga aattaaatta tttaaaaacc tagaggtagt aatgttaatg ggagatgttg
     8821 caaaaaaatc ttttaatatg attactaaaa agcatataaa aaagaatgtc atcccttcca
     8881 tttcaacata taaacttcgt aataatgaac tttattatga taatttaaga gtatttccat
     8941 catatattat gactggtgga aacatactga ttgaaaaatc aaaatttgaa atggcatcag
     9001 aagatataaa aaaaatgttc gagattataa acggttgata ttacaaaata ataaaaacta
     9061 atataaaata aaaagtgcct caaaaacttc tatttatgag gcacttttat tttatattag
     9121 tgtaactata tactattaac ataatttatt atttatattg ttctttttaa tctctattcc
     9181 atttagtcta ggtaacatta ctctttacaa gattacttta tatttctttt atatctctaa
     9241 cgtttttatt taataaaaca attattaata caagtcaaat atatctattt atctaaaaat
     9301 atatctttta cagtaatatc tggatggtga tacttcttcc tattcgttaa aaaagatttt
     9361 tttacattaa tagcctcttt tggacaccag tgaaaacaag ctaggcatct ttcacactca
     9421 ttaccccact ttggcttttt atcaactata cttatattct ctacaggaca aaccctttta
     9481 catgtcccac atccattaca tttattttct gcaaaaaatt tagtagttgc aatttgcata
     9541 ttcttaccta ctaaacgaag tacaacacta tctatatgtg actttaaatt gttttttcct
     9601 tctatatttc caatctccaa gttattgata cattttgcaa tctcagctac cctattagtc
     9661 tgatttttca atctttcttc ttcaacatct ggaggtgtta tcaaagcatt tccaggcata
     9721 ttgattaaaa aaccagcaga taattttttc cccctttttt taagtaactt atctatagta
     9781 aataaactat gtccagctac cccattacaa gtggcaatgg catatatatg agtattaata
     9841 ttaaaattta atttctctac aaaagacttt actatatcag gaacatcagc aaaataaaca
     9901 ggaaaaacaa ttaccaatat atcttcattt atgtctatat tattttcttt tctatgtata
     9961 gctaagggta taacttcttt acttccattt aacgtttctt ttaaaatatt tgaaactact
    10021 agcgaatttc ctgttccaga aaaataataa atcttactat tcattcttat ccctctttct
    10081 atatttctac atcatcaata gttaaaaagt ctcttaaaat aggatttata tttactttcc
    10141 aattctatcc aaaatatcag taaacaaagg caattcttca tcagagatag atttaaatgt
    10201 ctctgttgca tatatacttg caatttcatt taatggttct tctaattctc tacctaaatc
    10261 tgttaggaat atttgaaact tacgtctatc tttaacatct actttacgga caattaatcc
    10321 cttatttttc ataacatcta aaattcttgt tgtattagat ttatccttac atgatttttc
    10381 acataaatct atctgagaaa tcccatcttg ctcccataga aaccttaata acgcataatg
    10441 gtcagttgtt atatcatatc cattttgttt aaacatcttt tttaaatcat cttttacttt
    10501 taacgaagta cttactaact tagttgtagc ttcatatagt ttctcaaaat ctttcatttt
    10561 acctccattt aaataatccc ttgctcctcc catctatcaa ttattccctt atattgctca
    10621 atatctttaa aagccattgg ctttaaaaca gcatttatag caataaaatt atagatttga
    10681 gaaagcacag gtggattttt cttttcctct atgcaataaa taaatttttt agataccttt
    10741 tgtatctttg attctacttt ttcagttata ggattttgat taaatccagt ttttatagat
    10801 aaactaccac aaacataacc tcccgaatct aagaccatgg attttataaa agaaattgct
    10861 tttgaaccac gtgcattttc atatgtagta actgctatac atggcttacg atacaataat
    10921 ctttcaagca tcatatgtgc tctatctgta aacaccttga aaagtccagt tacactactt
    10981 ccataagttg ggctaccaaa tataacacca tcactcttag taattatatc atgaatatac
    11041 tctactttat cattttgatt gatacacttg cccattttat aacaatttaa acaaccaata
    11101 caatatgatg gatttacctc acttaaatca aaataattaa tttttacatc tggtattaat
    11161 ctttctatat ctttatacaa gtaagttaaa acttttgatg tagctccatt ttttctaggg
    11221 cttccattta taactgtaat tatcatttct atatctcctt tttagttgtt atatcaacaa
    11281 taagtatatc aactataatt ttagctgtca atataaacca tttatttaaa gctatactta
    11341 cacagcttaa ataaaagttt tatttaacta catgtgctta tttaatcaac tataaatgaa
    11401 ttatttttaa taattgacaa actaaattaa tgataatata ctttatgtat tacaaatgta
    11461 agtagaagga ggtatagtat gaaaaagtta ccacatattt cagaagcaga atatcaagtt
    11521 atgaaaatta tttggaaata tgctcctatc agcactactg aagtaattga aaagttggta
    11581 gaaacaagta catggagtcc taaaacaatt caaacaatgt tattgagatt agttaaaaaa
    11641 ggagctttaa catatgaaaa aaatagcaga gtattcgttt atactccact tgttaaagaa
    11701 gaagaatacg tagctacaga aagtagttct tttttaaatc gtttttataa tggtactctt
    11761 aattctatgg tactaaactt tttagaaaat gataaactat ctgaagatga tattgaggaa
    11821 ctgagagaaa tcttaaataa aaggacgact aagggggata aataaatatg tatgccccat
    11881 tctttatacg atttttactc agtacattaa ccttatcaat attaattgct gtaattttac
    11941 ttgccaaaaa agtatttaaa aaacatattt ctgcaaagta ccaatacaat attggattta
    12001 tattgcttat aatgttaata attccatttg tccctcttaa atatattaat cttggaaatg
    12061 tatttaacta tttatatact tttaatcaac ttggaagcag tactaatagg acttctatga
    12121 taaaaaatag tccaaattct ataattaata actcaaatgc attaaacgat ttttcagtat
    12181 ccctaaacca agttaatttt gatagtttaa atattttatt actaatatca tggataattg
    12241 gaattttaat catgatagct attactattc attgcaacat taaaataaaa aatatgaaaa
    12301 aatcaataca aattttaaga gatgaggaga tagtatttat atttgaaaag tgtaaaaaag
    12361 atattggtat aaataaggat tttatactat gcaaatcacc tattataaat acacctatta
    12421 catttggata ctttaaacca cacattatat taccagataa gtctatatct aaattatctt
    12481 taaaagatat aaaatatatc ttacttcatg aattacaaca ctttaaaaat aaagatatac
    12541 tgataaatta tataatgtgc ttccttcaaa tattatattg gtttaatcct cttgtatggt
    12601 atgcatttaa agaaatgcgt atagaccgtg aaattgcatg tgatatttca gttttaaaaa
    12661 agcttgataa agatagtcat atagaatatg gacaaactct aataaacttt gtggataata
    12721 tttcaagacc atcaaatctt acacttacat cagatattgg tgggtcaaaa aaacaaataa
    12781 aaaagcgact attgaagata atggattttc ataatgaatc aaatacgtta aaattcaaaa
    12841 gcattttaat ttttacattg atagctttaa ttgtatttgg aaatattccc aaactatcta
    12901 ttatggcaga tatcaatgaa aaatatagac ctacaaatga acaaactgtg tacgaggact
    12961 taagtcagta ttttaaaggt tttgatggaa gttttgttat gtatgattta aaatccaagc
    13021 aatatcatat ttacaataaa gaaaaaagta aaacaagaat ttctccaaat tctacttata
    13081 agatttatag tgccttattg ggattggaaa atgggataat aacaagaaat aattcacata
    13141 tcccttggga tggaaagcat cattctaata gttcttggaa tgaagaccaa gacttatttt
    13201 ctgctatgga aaactccgta aactggtact ttcagactct agataaaaaa acagggctaa
    13261 aaaacataca aacttatctt aggcaaattg gatatggcaa ttatgatgtt tcaggtggta
    13321 tctcaaactt ttggctagaa tcttcattaa aaatatcacc tattgaacag gtagaattac
    13381 ttgaaagttt ttatacaaat aagtttaaat ttgaagataa aaatatagaa acagtaaaag
    13441 attcattgtt aatatcaaaa aaggatgggg tatcactttt tggtaaaaca ggcactgcca
    13501 atataaatgg aaaagatgta aatggttggt ttataggtta tgtggaaaaa aatgaaaata
    13561 cttatttctt tgctacaaat attcaaagca aagattattc taatggtagt tcagcatcta
    13621 agataacatt atccatatta aatgacaaaa aaatctataa tccttaatat atttactgta
    13681 cattctaaaa aattcacata attttcatat taattatcaa ttaaattcat atacaaggct
    13741 tattatataa acatagaaga tagtaaaact agcttaaaaa cataatataa taccctatac
    13801 aaatagtggc aactctccct cacatcctca attgttgcca ctatttaatt ttttgtatga
    13861 agttaaatat attttcatca tttcaacaat ttgggtgcaa tacaatctct attttgaaac
    13921 aacctcttta attgttttag agtttatgaa ttatttctca tactttaaaa agattgaatt
    13981 actcttgata atcttctttt gtagtcatta catatcacct actactcaac acatattctt
    14041 tgacctattt ttacatcctt gtttatatcc aaaatattta ccttcttacc atctggaaac
    14101 aataccattg ttaaagtaga ctttcctaat tcatgtattc tctttaaatc aacattaaca
    14161 agaacatctc cctgtttaac catatctcct tgtttaacag caatatcaaa gccatctcca
    14221 tttaatgcaa ctgtatcaat tccaacatga attaatactt ctccattagt tcctttaatc
    14281 ccaaatgcat gtccacttga aaccactgtt tctaatttac ctgaaatagg agaaacaatt
    14341 tttccatcta taatatcaat agcaaaacca tcacctaaca tttttttaga aaatgtttca
    14401 tctggtacat tttctaatgc aacaattttc cccttagctg gagacacaaa gttttcatta
    14461 ttttcattaa acactaattc ttcgtcttca tcttcattta tagcttcttt aggcactcca
    14521 aataaacatg ttacaataaa gcagaatgca accacaaata ttgatgctaa taagtatgtg
    14581 attaaattat atccatcata gatatacatt aaataagaag gtaaaactgc taatccatat
    14641 gaattagatt gaatatgtaa aattgataat attgctgctc ctaaacctga agatgcacac
    14701 ataataatca aaggctttaa attatatcga agctgaatcc caaataaaac aggctcactt
    14761 ataccaaaaa gttgagatag cattgctcca actgcagttt gtttaacttg attattttta
    14821 gattttttca taaatgctag acatgttcca atattcgcaa atccatacat tgcacaaaga
    14881 gtaataaggg cattaaatcc tgtatttgct aatagtgatg tttcaatcat tacataagta
    14941 tgatgtaagc cagtaataac agctaatgga tatgtaaatc caataataaa tcctccaatt
    15001 cctaaaggca aatcaatcaa taagctgatg atatcaacca tttttaattc tattgtatgc
    15061 attatagggc ctacacctaa caaaataact aacattgtta ttagcataac aaaaaatggt
    15121 gtgaaaataa ggtctaatac attaggcata tgtttacgga accatttttc aagattagct
    15181 ccaataaatg ctgtaacaat agctgttaaa acacttcctt gacaacctac aataggaata
    15241 aatccaaatg ccataattgc ttcaatttca tttgatgggt cagcaacaga atatgcatta
    15301 ggaagtattg gggaaactaa cataagtcca ataacaagtc caataacagg tgttcctcca
    15361 aatactttaa atgctgacca tacaataatt gctggtaaaa aagcaaatgc tgtttctgta
    15421 agaaccgaaa caagtgtctg aatatacaat ggaatatttg cagaagacat tccaaataat
    15481 ccaagtacat tatcattaaa caaacaaccc tttaatccca agaataatcc tgttgctgca
    15541 ataactggaa taataggaac aaatatatct gctagagttc tcataacttt cttaaatcca
    15601 gtttcattat ttttaactaa ttcatcttgt tctttttttg ataaagtttt taatcccatt
    15661 ttttcaactt ctgcataaac tttattaact attcctgttc ctaaaataat ttgatactgt
    15721 ccagaagtaa agaaaacccc tttaacctca tcaacttttt caactttctt atcattaata
    15781 atttctctat ctttaaccat cactcttaat cttgtggcac aatgtgtaat agaaataata
    15841 ttatcttcac caataatttt aataagctca tttgctattt tattatattt attcattttt
    15901 ctacctcact ttcaataata ctgcatgaaa tggtttcaaa cgcactgttt tatttaatag
    15961 atttatatca tctaaatttt ggaatacaat atcatatttt tcttctactc ttatttctac
    16021 aggtttatca gaaaaattat aataacaatc aataactacc aaatctaatt gccttctata
    16081 cgcaataata tcatcacttt ctatatcaat aggttctatt gaaccataaa tcaaacaatc
    16141 agaatactca ctatcttgtc tcaactttat catcttttta taaaattcta aaatactctc
    16201 tgaattgtta atctgactct gtgcattaat atctttataa ttttcaataa cctttaacca
    16261 tggtgttgta tctgaaaaac ctgcattttc tttatctgcc catggaaatg gcgttcttgc
    16321 attatctcgg cttcttaaat tcacaaattc taacgcttct tcttctgagt aaccttcatc
    16381 tattgaacga tagtattggt caatgctaga taaatcatta aaatcattta tggtatctct
    16441 tttaaaattt gtcattccta attcctgtcc ctgataaata aatggggttc ctcttaaaaa
    16501 gaaatacatt gctcccaaca tttttactgc atcatcattc ctttcgtatt gcaaaagata
    16561 ctttgttgta gctcttggtt ggtcatgatt ttcaataaaa ttagctgccc atccatgttc
    16621 ctgaacatac atttgactat ctaaaatgca ttttcttaaa tctggaattg tccatgaaat
    16681 tcttttaaac cactcactac cagaagcaac atctaagtca gcatgtttaa agtcaaagac
    16741 cattgaaaag aaaccatctt ctccaataaa atcacctaac tggtcatagc taatacctgc
    16801 tgcttcagca acagtcatac aatcatattt tttaaacgta ttttctttta attcataaag
    16861 cattttttct attccaggct gatttctaac tgtttttgta catttaacaa gaccatcaac
    16921 accatcactt tctaaacttt gaaaacttaa attctttttg atgaatgtaa tagcatcaac
    16981 tctaaatcct gccactccca tttgagacca ggtattaatc atttggtaaa gttcacttct
    17041 taatattgga ttttcccaat taaggtcagg ttgttttttt ccaaaagaat gaaaataata
    17101 ttcgtctcta ttctctacct tttcccaaac acttccacca aaaacagacc tccagttatt
    17161 tggcaaatcg tttccttttt taaaaatata ataatcatga taaggacttt ctggattttt
    17221 taatgcttct tgaaaccaag gatgttcatc acttgtatga ttaagaacta aatctaatat
    17281 aattttgatt cctctatctt tacttttttt aattaactct tttaaatctt ccatacttcc
    17341 aaattcactt gcaatatcca aataatcact aatatcatac ccattatcat ccataggtga
    17401 tttaaaaatt ggacataacc acaatgatgt aatacctaaa tcttttaaat aatctaaacg
    17461 agaaataatt ccctgtaaat ctccaattcc atcattatta ctatcttgaa agcttcttgg
    17521 ataaatttga taaacgattt ctttttgcca ccatttcttt tccataaatt actccttttt
    17581 atatgatatt tcttcttttt aattctttat aaattccatt atcgaatatg tcctcacata
    17641 tagatgtcgc tatatcttta agttgttgat gactattttt cattgcaatt gtaacgtctg
    17701 atgcttgaaa catgacaatg tcattttgac catcaccaaa acatatggtt tctttttgag
    17761 ttactcctaa tctttcttgt aatctcttaa ttgctttgcc cttatgaaaa tctttttgaa
    17821 taatttcata atactgacta gaaatatctc tctgtgctaa ttccatttta tcttgtagta
    17881 tatctttcac ttcgtcaaat accttttcat ttgaccataa acaaatttta tgtatatctt
    17941 gtgacttata ctcttcaatg ttattttcat atgttatttt ttcttggata tgttgtttat
    18001 ttatacaaga attagttcct ttcaactgat tcattgtttc aaatatttct ttggcttttt
    18061 gattcatgaa aactttttcc tgactctcaa tcgaaaaagc aacttctcta ttttttaata
    18121 aacaaacaac ttcctttatc aatctttgat taaaagattg attataaagt aattcaccat
    18181 gatattgaat gtaattacct cctcctgcaa tatatccatc aactcctaat gataaaacat
    18241 catcttgtat tgtacccata cttcttccag tacaaataac aacactgcaa tgattctttt
    18301 gacataaacg tatagcatgc tttgcagatt ctgggattcc atatacctca tctctaagcg
    18361 taccatctat atcaagtatt aataatttgt acaatttcat cttcctttct tactatcaaa
    18421 atcataatag cattcaaaaa aaaagatatc aatattttga tatcttttaa aaaatatgtt
    18481 catttttagc acaaattttc attttcgggg aatatgttca ctttctaaat acatcttgta
    18541 tttaatataa agcagttcaa ttaaaataaa ataaggtgtt gttacatcgt agtccagttg
    18601 tttatctaca gaaatagata tagattgaat atacaggttt tcatcacata atcttgctaa
    18661 aggattactt atcatttttg taatagaaac catataaatt cctttcattc tcatttcttt
    18721 agcaaaatca ataattgtag atgcatctcc attcaatgaa ataaagaaaa tcatatcatc
    18781 tgtttttata aaatgattaa gtgcctgaat catatcataa ccataaacat catatataat
    18841 tttccctgtt ggtaagaaaa tccttttcat ctctttagca actctttcct gagaataacc
    18901 ttctccaaag acgattatac gatttgcctt tttcattctt tcaaacataa tcgaacaatc
    18961 cttcttctct atatcattta tcaccttatt atagcaatcc attaattggt gtttactttg
    19021 atttttatat tctacttctg tttcatttaa gcgtataata actcttaatt cactatatcc
    19081 aggtaattgt agtttttgag caaaacgaga aagtgcactt gtagatatat ggtatttgtc
    19141 tgcaaattca tctatagaaa gtttaataca atcttcttta tgattaagaa tacactcaca
    19201 gatatactta tcatttgctg taaatgaatt ataatattta ttgaaaagtc cttcaatttt
    19261 cattcttttc tccttctata ctctatgtaa ttcatatgaa gcaaatctaa tagagcataa
    19321 aatgctccta cgacttcata agatatagct tgtaatgtat caagtttttg agtttcaaca
    19381 tacagattat actcacaaag tgttgcaatt gtattattat caagcctagt taaagaaatc
    19441 gtatgtatat gattgttgat aaattttgca atttcaattc ctgcttttgt ttctccagac
    19501 aaagaaatga taataaataa atcatttttt tgaaatgatt ctctcataaa ttcaatttca
    19561 cctatatcaa ataagtcaat aacacattta cctactgaaa gaaatattct ctttatttct
    19621 tgagctaaac ttttctgttc attacctgtc ccataaatat aaattgtttc tgcatcatat
    19681 attattttac aaatatcttg aaatgatatt ttttgtaatt cattcattaa tagtcgataa
    19741 ttctcgcaaa catcatgaaa attattatca ttattaacaa attctagttg attattttta
    19801 agtaaatact ttaaatcaga gaatgaatct aatccaattt ttctacaaag ccttaataaa
    19861 gtagctctag aaacattaca ttcatttgca attttttcac acgaaaaatt acggtattct
    19921 ctttgacaaa tcaatatttg tttaataata attttatcat tttcatttaa attatcataa
    19981 ttttggttaa ctaacgattc taatctcatt ttttccactc cctaaatatt attttaatat
    20041 acattagttg ctttttctag ggaagagttt taaataataa ggataaaata atcatttgat
    20101 tttattttta ttaaaataaa aataacctgc taaaagcagg caccaaaaag tacttatcct
    20161 ttcgaacatg tactttagat attgctttct tcggaagctt catctcttca tactctaaaa
    20221 tatagttttt tctaactcaa aagtattttc catagtagaa attactttaa ttcatctgcc
    20281 atttactttt tatcttattt aataattact attacttgaa tatttacttc tttaagtaaa
    20341 tttcatagtt aacaaagcta aaactattat tatagatgtt aaaatacaaa attgtaagta
    20401 ttgttataaa tatgcttaca gctacaaata tacatgatat attaaaaaga agctgtaaat
    20461 tattatcata catacaagca actatgcctc tattaatcca tgttaatttt tattatttaa
    20521 tacaaggagt tccatgagac atacatatcc attcatattt taaattatcc aattctctta
    20581 tagatttcac catcttttta taatcccaat tccatggatt aggataagga actatatttc
    20641 cattcttatt tttgactaaa tcacctgcaa ataatacagc ttcaaaaatc atgcagacat
    20701 gccctggagt atgaccagga gtatggataa tttttatatt cccaatctgc atattctctc
    20761 cataaggttc aacatcctta atgagccttc tggaaattgc ctttccaata aacttcttaa
    20821 acccaggtct atccttctct cctataataa aaggtatatc ctctacatga gcccatactt
    20881 ttgctcctgt tttttctttc aataatttaa tattagatat atggtcaaca tcatgatgag
    20941 ttaataaaat atgcttaata tctgtaagtt taatgccaag tgtttttaat tctttaatta
    21001 tatttttccc cataaaagga agacctgtgt ctataagaat aatttcttta tcaaacacaa
    21061 taaaacaatt tgagccacga gtactatcta acattaatac attttctttt atcttcataa
    21121 ataaattccc cttatttggt attttaccta tataattaat taataaagtt ataaatagtt
    21181 ataatacttg atattaattt tattttttat taaagtatac tataggtata caagtattat
    21241 atttacataa gtataccatc agtatacttt tttatcaata gaaaggaata atttatatgt
    21301 cagaattatc aaaaagagat aaagaaaaaa tacaaagaga aaatgagatt attgataaag
    21361 cagaaaaatt attttgtctt aatggatttg ataatacaac tatgaatgaa ttagcaaaag
    21421 aagttgaata tactaaacgc accatataca agtacttttc atgtaaagaa gatttattct
    21481 ttgctgttgt cttaagagga tataaaagac tttgggataa tgttaaaata gaaagtgcaa
    21541 aaggcaaaac agggtttgaa aaaataaaac tttcatactt tgcttttcat aaattttact
    21601 ctgtagaacc ttctctatta tgccttatgg gaatgattgg tattgtaaac tctgaaaaat
    21661 cggatactga tatgctgttt aaagaaaagt ttttttcttt taataaattt atgtttgatg
    21721 aaatacaagg aatgtttgaa attggaaaaa atgatagaag tattaggcat gatattgaaa
    21781 tacctactct tatgtattca tcaatattta cacttacagg attttttaat ttactatctg
    21841 taacaggaaa atcatacctg aacaacttta atatagatga ggaaaaattt attgaaacaa
    21901 ctcttgctct tttaatagat tcaattaaag cataaaccta agtttataaa ttaaagttta
    21961 tatacttaaa tgataatttt ttctatctct aatataaaaa atattaaaca taaaactaat
    22021 aacttagtta atggaataac taaattactg aaaggattaa aagtaaatgg ctaaaatact
    22081 tcttttagaa gatgatgata caattacatt tggaataaaa acttcccttg aaaagaaaaa
    22141 tcacactgta tgttgttata atacgattgc tgaagctaaa aaaaattttg ataaaactat
    22201 tgatttaatt ctgcttgatt taaatctacc tgatggtatt ggatacgagt tttgccaata
    22261 tgttaaaagt atagaagata ctccagtgat atttttgaca gtccgtgatg atgaaaaaga
    22321 cattatacgt ggattagata tgggtgcaga tgactatgtg gttaaaccgt ttttgctctc
    22381 agtacttcag tccagaatta atgcagttct tagaagaact cattcaaata ctaacaatac
    22441 tattacatgt gaaaatataa gcttgaataa ggttgaagtc aaagcatatt tagataatgt
    22501 tgaagtacct ttgacagcag gagaatataa acttcttcta agtcttatgg aaaataaaaa
    22561 tagagctatg actcgtacaa agttactaga aatgctctgg gatgtagatg gtaatttcgt
    22621 aaatgataac actcttactg ttacaataaa acgtcttaga gaaaaattaa aaaatccacc
    22681 ttgtataaaa acgttaagag gcataggata tagaatggag gacagctagt gaaaactcca
    22741 agaaatatca acagtacagt tgtttttata atattctgct taattgtaac ttttttattg
    22801 agtgtaattc taacaactat aacttctttt aatgaataca atgtactgtc taaggctctt
    22861 ggtgcatcat atgagtacaa tcctaagtct acagaaagta tactaaaatc actgaaaaat
    22921 tctagtgata aggattttaa aacaggaaat gaaattttat caaaacatgg atattctaaa
    22981 agtacatttt ggagtaaaaa ctttttttat tttctagtga tatcgtttgg tataatttca
    23041 acaatggcta cagttatata tataatcaaa catagaacaa ataagcaaaa actgagtaga
    23101 ataaacaatc ttactcaata cttagaagaa gtgaatttag gaaaagagtc tgtactttta
    23161 cgatgtgaag atgaattttc tcaccttgaa gatgagatat ataaaacagt tggggaactt
    23221 cgttgttcaa aagaatttgc tttaaaagaa agacaaactc tttcagataa tcttgcagat
    23281 attgctcatc aacttaagac tccaattact tctatgtcac ttatggcaca attactttca
    23341 gaaaattgtc cagatgaaga aatagattat attaacagac ttacaaatca aatctcaaga
    23401 cttgagagac tagtttcatc tttacttaca ttatcaaaat tggatgcaag tactttaata
    23461 tttgaaagca aacttataga tgtacattct cttcttactt atgcaattga gcctatagaa
    23521 ggttctttaa gagaaaaaca tcagacattt actatcgagg cttctccttc ggtagaattt
    23581 gaaatcgata ttaattggac tttagaagct cttttaaata ttcttaaaaa ttgtagtgag
    23641 catatagaag atggtggata tatagttgct tattatagtc aaaatcctct atatgttgag
    23701 attatcatag aagataatgg taaggggttt gctcaggaag aacttccata tatttttaat
    23761 agattttatc gtggtaaaaa tgctagtaag gacagtattg gtatagggct tgctctatca
    23821 aagtctatta tagaacgtca aaatggtact ctacatgcag aaaattgcca taatggtggt
    23881 gcaagattca taattaaatt ttacacataa aatgctggat tataggtaaa atacctataa
    23941 tccagctata tctatattct atgttatcta ttgttttagt aatatacttc tatttacatt
    24001 taaggtttta ttaaacaaac aacttaacta tccctatact tgtaagtagt cttaaatcga
    24061 aacctttaaa taagttcaaa tagattttgt ttatattgtt tcatttttta tagattctac
    24121 tatattttca ttcttcaact gcttgtatcc tgtcatatat gatgctatta caataaaaag
    24181 tatcaatata gtaaaaccta ttattgtaga tataggtgca aatggtaaat actctataaa
    24241 atatatttca tttatacgta gaaaagcata cactattcct atttgcacag gaatactaag
    24301 tagtaatggt gtaattccta agaataaacc ttccaaaata agcatctttt ttatgccttc
    24361 tggagataat ccaacagaac gcaacatagc aaactcttgt cgtctacttc taatatttcc
    24421 tgacactgta gcaagtacat ttgataatcc aatcatagcc aataaacctg taataaagcc
    24481 tactattaaa ttcatggtct ttattccact agccttttgt ttttcacttt ctaaaacatc
    24541 ctcaatacta taatctcctg aaccatagtc tttattataa atggactcta atttttctct
    24601 tactctagga atgtcctcac gattatttac tttaaatact cctatcagcc tatttgaacg
    24661 taacctactt acttcatcat aatttttaga tatttcctgt accatagaca ttggaactat
    24721 ttgcattaat gtatactttg aactagtatc tactatttta ggaagtgtgc ttgtaatagc
    24781 tcccactttc atgttgtaag tataatcccc tttatcttcg tcatatactt tttcatttaa
    24841 tttaatgtta tctcctattg aaagatttaa ataatctata tatactttat ttctacgtgt
    24901 actacgatta atatcttcct ccttattata tacaattgag gttggatttt ttgtattata
    24961 aaataacttt gggtctacag aaatttgcct acaatattct gtaaaactct tatcatcaag
    25021 cccaattata tttgaaatta tacgaaactt gccatcacgt tctataggag agtatttttt
    25081 agatgaaact atacttttaa atcctccatt tttcgcaagt tcttttgatg catctttttc
    25141 agtcagccaa gtggaagcag acattttttg ataatatagt gaacttttta caccttctgt
    25201 attatctaat ttttcaatga aagcagactc tataggttca ctattttcca aataaactgc
    25261 tatatctctt tggtccttat aattatcact tccataaaca gcttttgctc cttcttgatt
    25321 tgcaattata tgcaaaaaac atgtaagtaa taaaaaagat aatgttaaag atattgttgc
    25381 agtacgataa gattttttac gagcacgtag tgcgtttgat gcaagttctc cttctattcc
    25441 aaatatcttt cctaatgaat atttatgcga ctttttgatt ttaacactat ctccttgtcg
    25501 tattgcttct ataggagata tctttgatac ttttcgtgct ggtataagtg cagaaatcca
    25561 gactgttact attgtaagta aaactgctgg cagaaaagca ggaataccat aagtaaatac
    25621 cacttctgga acatcagtat gataattaac tgaattaaca taaactataa gcctattaca
    25681 caataaccat cctaaaaata aacctattgg taatggtata attgtcagta aaaagccttc
    25741 aaacactaca gaccttttaa tttgttttgg tgatgcacca acactagata atatccctaa
    25801 ctgagtaagt ctagcatttg cagacagtga aaacgcgttg taaatcacca ttacaaacac
    25861 ggctactgta aaaattgcta ttgtaagata cataatagga gttgaaaatt ttgatatact
    25921 actcatagat gctttctgtt ctggtgaaaa gactaacatc tttaaaagat aattactatt
    25981 gtatttaaga ttgtattttc catattcatt agtcttccat cccaatgatt tagcaagttt
    26041 tggaagttcc ttatacgtgt ctcttatatt tttaaatcgc aagtacacag ttatactatc
    26101 attaggtttt atacttgttt tatcaagata tccaagagct gtatatgcag gtattactga
    26161 tgaagtagaa acatctacct ttcctactat tgtcaatgta gcctctgaaa tttttttaaa
    26221 actttcccct ttcgattttg gggctatggg ttcaagaggc tttccattta agattctata
    26281 tcctattggg agagtaattt tatcaccaat ttttacactt ggattattct caaaatattg
    26341 ttttgataat gcaatttcat tagcattatt tggtcgacga ccctctatta tagtatcctt
    26401 ttctggcata gaattccaat actctgatgt agcatttcta taaattatat aatctctttt
    26461 ctcatcatta attttgccta cataccattg tccttttacc attacatcat caactgaaga
    26521 aaaattttca attaatggta agtcacttcc ataagtatag tcaaacaatt caccatgcca
    26581 gttaccttct ttctcaattg aaagtcttat aaaatctgtc cacatggtat acaacagtcc
    26641 acacaaagaa gacatcatgg ttgtagtaag taatatagct aacattatag ctatactact
    26701 acgtttattg cgtcgtacaa agtctaaggt gtattcttga agaatattca tttcttcacc
    26761 accttttcag agacaatcac tccatcttcc atagttacaa tacgatttgc ctctagtgct
    26821 attttctcat catgagtaat aagaagtatt gtctgattaa atcgtttatt tgataagttt
    26881 aacaagtcta caatttcttc tgaatttttt ctatcaagat taccagttgg ctcatctgct
    26941 aataaaatag ctggtctata gattaaactt ctagctatag ataccctttg ttgttgtcca
    27001 cctgaaagtt gacttggaag atggtttaat ctatcagata atcccaatat agatacaatc
    27061 tcagagaatc tatcctcatc cacctttctt ttatcaagta acatgggtaa taatatattt
    27121 tttctaacat caagggtagg tataagatta taaaattgat aaataagacc tacttttcta
    27181 cgtctaaaaa ctgcaagagc ttcttccttt aaacttgata tttctgtatc ttcaacataa
    27241 atctttccag atgtaggtct atctactccc ccaagcagat gtaacaatgt agatttgcca
    27301 gaaccagatg ctcctacaat ggatacaaaa tcaccttttt gaactgataa atttacatta
    27361 ttaagggctg tcactctggt ttgatttgaa ccatatattt ttgtgagatt ttcacatttt
    27421 aatatttcca tatacaatca tctcctttat ggttaaattt tagcaaccta aaatgacatt
    27481 atagtgacat gaatacaaat ataaattact attaaaaata ttgtttagtt tttgcacatt
    27541 atttaaaatt ataatataaa acaaaaacta tgcaatatat tttatttata cttttaatat
    27601 attacatagt ctttaaaagg tattaacttt aaatctatag gtattcaatt taataatcaa
    27661 tagcaagtat tttatgtact aaaggagttt tgctctatat agactcaatt tagtaaaatt
    27721 atttaataaa tattacagac tataggtaaa taatatttac aaataaaatt aagtttattc
    27781 ccttacacta taatatttct taattatatt aattgcaatt tcctttacct ttggccctgt
    27841 aatttcttta ttggaatcat ctgatttaat agcaaaataa taggtgtcac cttcacgctc
    27901 tagcatacca acaaaccatg catccacacg tttatttttt tcatcaaatc ctgttccagt
    27961 ttttccatat acatttatgt ttttatcatt tatatctatt ttcataatat ctcttaaaat
    28021 attaatatgc tcttttttaa agtttgtatc tccctcaaat atttttgcca ttgtttgcac
    28081 ttgttctttt ggagatattt gtaatgaaga ttctaaccaa aatccattta aatgtccctt
    28141 tccatttttt aaatcgcctt cccattcgct aatatcgcaa ttcccatact ttaaatcatc
    28201 taaaatgttt tggacagatt tagcatcaac tttatctatc aattttttgt aataccaaac
    28261 acaagactcc ttaaatgcct cttctaaact aagattttta ttccaatttt tatttggata
    28321 ctctgtacca tcatatccca taactgattc ttttgagttt attacccctt tttctaaacc
    28381 aattaaagtt gaaactattt taaaagtaga acatggtgac cttcttgttt caattaattc
    28441 tttgttatat atattatatt ctttattttt agtattataa aaaatagctc ctccactaat
    28501 accttcaaaa caatcactat agtcaaccat attaattttt tcttttttgt ttttatcatt
    28561 gttttcaatt ttggatttat ttaattcaga cttatttaat tcagatttta tataattctt
    28621 atcagttttt tgatttatat cgttatgttt tttccctaca taatacatta ccataactac
    28681 accaaccaat aagatagcta tccaaataaa attctttttt cttttcataa tttatatcat
    28741 ctcccatatt taaatttata acctactatt aaaatagtag acattatttg taatatactc
    28801 caatctaggt tctacttata agaaacaaga ctaaatgaat agctgtatct cttatatttt
    28861 cttcacctag tacaattatg ttgattaaac ctattgcgaa gataattagg taactattaa
    28921 taacatcctg tcctcctttt aatttgtgat ataataattg attccacatt taaaacttac
    28981 tattgtaata tttaaatatt acaatagtaa gttttaaatg tcaagttagt ttaggaaagt
    29041 tattttaatt gtataattgt tattacattt ataaaatatg gcatgtttaa aattattttg
    29101 ctattgggag gattaagata agcagtatta taaaagctat aaattataaa atttaatata
    29161 taatttatag cttttacttt tacaaatatt gtttttattg atttattaat gaattttatt
    29221 gacaggttat atttatataa gtaaacactt acataataag tatataatct acatatctat
    29281 aagttgagtc aattcacaag tatatgtcaa cttaagttta tgcatagctc gtgtacaggc
    29341 aatatataac aaactgcggt cataatcact ataatatgtt ttattattta ctgaaggtac
    29401 aataacttca tcaaactcta aaccttttga cattttaata gaagttatgg atactccttt
    29461 tgtaaagcta gaactttcag aagatattaa gtgaacacta tattcttctc ttaacgcatc
    29521 atatacagct ttagcgtcat tatctgtctt taatataata ccaagagtcg cattatcact
    29581 ctttttaaat tcttcaattt ctatttttat cttatttatt tcatcttgct cgttattaca
    29641 ttttaataaa gctggttctt caccatgtcg ttcaataggc tctaatgaag atatgtcttg
    29701 aatctttttg gcgaaattaa taatctcaaa agtagaacgg taactcttgt tcaacataac
    29761 taattcccca tcattatata gctgtttcat atcatctagt gtatgagtat gattaggatt
    29821 aaccaattgt ccaaaatctc caagaatagt ctttttacac ttaaaaagta agtttattac
    29881 agcatattga ataggtgtat agtcctgcat ttcatcaata acaatatgcc ttataatctt
    29941 atcttcttgt ataccttcat atgcagcatg aatatatata aatgggtata catctgacca
    30001 ttcaagtgtt ttcttttctg ccatcacaaa catgtttgat atattcattt gtttaaagaa
    30061 atccttatat agtgtaagag tattttttat tgtcaacatt ccattcaaac ttttaagtat
    30121 actttttacc tttggtaaat cttcttccat aatattatct gattcaaatt tataatgaat
    30181 gtcttcagct accttctcta atctcttctt aactggatat ctgttatatg cctcaaatct
    30241 actctgtatc cagtcacttt tagctgtaaa acttccaaaa gtgtagtctt ttggaataaa
    30301 aatcttattt ggcatttgtt ttatataatc atcaataagt tttacaaaat caagtgtaga
    30361 tttaaaacgc actctttcag accatttagc atcatttatt tctaatgggt ctttctcact
    30421 ttcaaaatta ataactctat ctaattgtac ctctgctata ttttcaaaac ttaattcaca
    30481 taatggctct tctccaagct caggaaggac attggaaata tagtctccaa agactttatt
    30541 aggtgatagg ataattacat tatttgctga tattttatct ttaaatcgat aaagaagaaa
    30601 agcaattctg tgtaatgcta tagatgtttt cccagaacca gctacccctt gaataatcag
    30661 tgtatcagct ttatcatttc taataatttg attttgttcc ttttgtattg ttgaaatgat
    30721 tgacttcatt ttttcatctg aagtgtgact aagttctttt tgaagaatat catcttgtat
    30781 attaatggaa ctttctagtg catattctaa ttttccattt ttaattttaa attgtcgttt
    30841 tcttgttatt tctccatcca cccatcctat tggagcatca tatccagctt ttccgatttc
    30901 ataatcataa aacatactgg caattggaga acgccagtca agtattataa gctcatcttc
    30961 ataatcaaat gcaaatctac caatataata cttagattca tcatccatat ctttcaacct
    31021 aaaatctatt ctagcaaagt atggagaatc tttgatttta ttaatcttat ctcgaacttt
    31081 taccataaaa gccccatagt tatctatttg ttttagtcct tgttcatttt gaaacatttc
    31141 atgtgggtct atttcaccac gattttttac catatacatt ttagcatcca tataatcctt
    31201 atcaagcttg tcaacaagat tttcagcttt cttaaaagca ttgtctagct tgttatttat
    31261 ctctattaga tgtgcaatct catctggaaa aaaagttaat aactctgcat catattcaca
    31321 catattatgt ttagaattag atgcaataat atcgcaattt actacttgtt tattttcaga
    31381 catttaaatc ctcctttgtt aattaagtac ttacactgaa tcattatact taattgtgtt
    31441 ttggagtttt taatcattct tgctatttaa cttaaaggaa gaataaattt ttgagtagga
    31501 tatccaaatt ccacaagcaa ttctgcttct gcaaagccca acttctttat catatctcta
    31561 tgtcctgtat cagctttgtc accctctcga aaggtagtaa ttgaaatatc tgtatctatc
    31621 aagaaatctt caataacttt cttcaaaaac acttgtgcaa tgtctgaatt acgatactgt
    31681 ggatgtattc caaaaaaatc aatacttcta gtttctctat taaacaccat atttgcaata
    31741 gcgacattat taagttttaa tattaaagct ctttcttcta aaatatactg ttctaattga
    31801 tatatatatt cttcctcttg caaattggga aatccatcta tgactaatct cactaaattc
    31861 atccataatg gtatgtcaga catacttgca agtttaattt ctttttccaa ctctagtaca
    31921 ttctttgaaa ataggttatc ttttttcaaa acaaatctta gctgcaaagg ataaaattct
    31981 tgttctttcc tatatttatt tggagatttt ttatacatag ctttaaatat agaagtgaat
    32041 gcctgttgac tttcatatcc agctatcaat gcaatttcaa taattggttt ctttgaaaat
    32101 accaataatt ttgctgcttc tgtcaacttt ctccgcttta tgtaatcatg cattgttagg
    32161 ccaacagaag ttgtgaaagt tctatgcagg tgatattttg agtaatgaac agcattagca
    32221 actatatcta aatccagctt ttctgataaa tgctcctcta tatagtcaat agcagttatg
    32281 acattaatta ctttgtaaga cattgcagct tccctccttt tatccatgca acattatatc
    32341 aattattact tagttatatt taatgaatct tgctatttta taaacaaatt tgttgtttaa
    32401 gttttcaatt cataaattta atatattact ttttactttc tgattaaaga ctctaatcct
    32461 ttaattttca ataacttttc atttagtaaa tctaaaaagt tatttattat tttcttctta
    32521 ttagattcct taattaaatg ataaatattt atattatacg actaaaaaca gctttttaca
    32581 attatttaat atgattacaa acttacccta tcttaaagtt taatggggtc ctgttatgaa
    32641 tctttttatt ttaatttaag ctcttcatca gtttatttta tatattgatg tatttgattt
    32701 catacaaaaa agagtgcttc atgaactaaa aagttcattt ttaaacactc tcttttatgt
    32761 aaataaattt ctattctatt ttgaaatatt ataatttgac ttataatcta ttaataccaa
    32821 aaataataaa ttgtacgtct aagaatagat tctaattagt tgctcagtag taaaatctgt
    32881 ttttaactaa tcctgctttg tatgttgaac atattctata attgtaccat ctggatgtct
    32941 caatgtcata ttatatcctg taggaacttt tttcttatct cttactacaa ctgctccatt
    33001 atccaataga taacttctcc attcatcaac agaatcaacc ataaaagtag attttgtttc
    33061 tataaatggt ttaagagcat catcagaacc agataatagt aaaacatttc ctatttgcgc
    33121 taattccaac ccaacttctt tataggaaaa acgcaaagaa catttttctt ttaaaagatt
    33181 ctcataaaaa ggtatggctt tttctatatc ttgaatataa aaacgtgtta atatatcata
    33241 tattttcata ttttccccct atatatctat ataatattac ctctaaatta taccactcta
    33301 caaattatat aacaataaat taagcatagc cttttgagca tcttaagtag accttaacaa
    33361 tatattgggg ttacattaga atacataaat taaatcacct tgatattatt taggataaaa
    33421 tttatgtagt agcagtaaat gttcttctaa ttatcaacta acaaacgata atctttaact
    33481 ttctatataa tgggtaacat cattttcgta agatattcac tagctggacg attgatatca
    33541 tttaaatact ggtaatatat atcgccatga agtttatatc cattgctatt tgcccatgaa
    33601 aataagtctt ctaaagtagg gtcttgtaat tcataaggtc ctaaatcaat tgcagttatt
    33661 attttctgtg caggaacaat cttttgtaga atctcatttt tcccatctat ataagtggct
    33721 acaggaaacc ctacttcaac atccaatttt actaaatcca tgttatgaaa acatacaatc
    33781 ggtgctcctg aagataaaat tcctctctcc tccagatatt tagaaatttt ttcaaaactt
    33841 tgttttgaaa actctgaaaa ttctaccata aagtcaattg tttttcgtat tgccaaaaaa
    33901 cagtactcag attgttcagc tattgttata ttggatattc tagtcatttt attcctccat
    33961 tactttattt tcatttctaa tctttttata ccaaattata cgaaaattca ctgtgtaact
    34021 aattatttca tatgaatata aaacataacc tccttccatt tcttatatcg aaagtatagc
    34081 aaaaataatc tcatcattct tgtcacacag tgctcttata atcagaacat acttaaaaga
    34141 cttgcctaat ttttaggcaa gtctaaaaga aatctttttc tataaaaaat ttatacaaac
    34201 aattaaaata tcaaaatata gactaatata aaactataaa tttactaatc tgaacctccc
    34261 atggctaaag tcacaagatt actgatttat agaatttcgc acactaaaat atgtcttact
    34321 aattccccac aggctacccc cctagttcct acgttcttac ataagttatc tattatcaaa
    34381 catcaaaatt taaacaagtt tcaggttcat cttctattct tgctatttta aacttacatg
    34441 caattaatac taaagatact attggattta taatatttaa taaagcgtat ggaccatatg
    34501 ttagtgcaga tacacctaat gttgctgtta tatacgcccc gcatgtattc catggtacta
    34561 atggagaagt taaagttcca ctatcttcta aagctctcga caacatctta ggatgtatac
    34621 ctctcttttt atattcctta ttatacattc ttcctggtat aactatagat agatattgtt
    34681 cacctgctat tatattggta attgtacaag ttaccatagt acataatact gttccaaata
    34741 caccctttgc taatcttagt aaagaagatg ctactacttc aagcatacct gttttttcta
    34801 aaatacctcc aagagataaa gcgcatattg ttaaggatac agtggacatc atattcataa
    34861 tcccaccttt agataataaa gcatctacct cctgtatttg tgttgacgaa acatatccat
    34921 tttgtgctgc atctaatatc gtattcatag attctccttg aaaaactact gcaaacaata
    34981 ctcccaatac agcacctact ataagccctg gtatagcagg aactttaaat acaaccaatc
    35041 caattactat tgctggagct aataataata ctggtgataa agtattaaat gtagaatcta
    35101 atgtagacct aattaattct atttgtttta tatctagtgc ttgacctgaa tacttcattc
    35161 caattacacc ataaattact aaacaaatta ataatgatgg tatagtcgaa tatagcatat
    35221 attttatatg tgtaaacaaa tctgttcctg ccattgctgg agctaagtta gtcgtttcag
    35281 ataaaggtga tagtttatct ccaaagtaag ctccagatat tatagaacct acgattaatc
    35341 caattggcat acctaaactt tgaccaattc ctaaaagagc tactcctact gtacccattg
    35401 tgctccaaga tgaacctgtc gcaagagata ctattgcaca gactaatgtt gatgctacta
    35461 aaaaaatatt tggtgataaa atttttagtc cccagtaaat catacatgga actactccac
    35521 ttactatcca agttcctata agtacgccta ttataattat gattaagatt gcttgcattg
    35581 ccatctttat actattaaac atacttaatt ctaactcttt ccatttaaat ccaagtctat
    35641 atacagccac aagtcctgct actgctgctg ctcctattag tggtacatga ggtgatgaac
    35701 catacactaa tactcctaga cttaaaaata atatcaaaca agtaattggt atcattgcat
    35761 caaacagact tgcttttcta cattctcgct ctttcataaa atagtttcct cctaattatt
    35821 taaacactac actataattt tttttgaaac atatttgctc gtactagatg acatgatacc
    35881 cccataagtt aataaaaatt ctaaattgtc acctaattta taatcatatt ttgtgttact
    35941 tacatctagt atcatgtggt ctgaacttgc ccctaatatt tttatatcag tgtctattgg
    36001 aattaaagag tcaatattta tatcttgttt acctatagct atgattgccc tttttaagat
    36061 tcccttatct tcataaacag gtttatttct aaaggcatca actcctattt ctccaatagg
    36121 aactgatggt ttttctttac attcaactac ttggcatatt aatttaaatg catcttgata
    36181 tgttccattt atattttcac cgtatgccgt ttctctacca agtagaatgg actcgcctat
    36241 tctcaaatta gtaatacctt ctggcatatt attatttatc aacagatgaa tagaacttga
    36301 attacctcca gatactattt ctagatttat tccaaatttt tcttccattc tttttgctat
    36361 acttaccagt ctgcctatat tttccctaga tggtataata gctccataac aggttaagtt
    36421 tgtagctata ccaattattt caatattttt taatcttact atctctctta cattattaaa
    36481 aaagtcttct tcataaaagt atccttctcg taaatcgcct aagtcaaaca taagaactat
    36541 cttatgaata atatttttac tttcacataa ttcatttaat ttctttattg ttcctaattc
    36601 tgagttaaaa ctaatatcgc aataattgat aacttcttct aattcactta acattgggat
    36661 tctaatcaat atcttaggta gatttatatc ttgtaaattt tttaagtttt gtattcttga
    36721 atctgctata tggtctattc cttcactaca tatttcttct actatttctt tttgtgcaca
    36781 aaatgattta gtaacaaaag atatcttaat atttctttca tgacacatct gcgaaattaa
    36841 ttttgcatta tgctttaact tttctatatc tatttctaac ctaggataca taatctttcc
    36901 tcctcaaaat tcaaactttt taacaggagc ttaagagatg cttcttcata ttttttagat
    36961 aaaacaccca tagatgccat aatatagtca ttatctatta atatctttgt tttttccttt
    37021 ggaaatagta attcattatt tttattgtat ttgagcatat tatctaatat ttcaattcta
    37081 ctagggagcc tagtaagtgc tccccctgta ccaactatat atcttacttc tgttaaatct
    37141 ttcccttctg caattttgac ttttccagtt gttccataga tatttcttat ttttcctgaa
    37201 tgtcttagca tagctttaac aacagcttct tttgtcaatc tttcaacaaa taatatttct
    37261 tcttttgatt ttggtattgg aggataattc tctattactg catcaatatc tatagatagt
    37321 tcactttgta agttttcttt acctataact tctactatat tcttcatatt tacatataca
    37381 cctaaatccc cctcaacact tctctttgca gtaggttcag gattaaccaa aattttatta
    37441 atatagtcac ttccatctgt aacagaatgt acatcagtag ttgctccacc tacatccaga
    37501 gttaataaat ctccaatatt tttatataaa agtttagaag cttccattac agctcctggg
    37561 gttggagtaa tattttcatt aaccatttct ttaatgtatt tcattcctgg tgctgtagtt
    37621 atgtgttctt caaatacact ttgaatgatt cttcttgtag gttctatatt caataaatct
    37681 attttagggt atacattttc agttatataa agcttataat tagtatcttc aaatattaac
    37741 cttatttcct cttgattttc aacattacca gcatatataa ctggtatgcc tagattcata
    37801 gaagctatca tttctgcatt ataaatagct gtatctcttt ctccataatc gactccacca
    37861 gctattaaaa ttatgtttgg gtttatttct tttattttat ttaaatcagt tcttttaatt
    37921 ctacctgatg ttatttgacg aataacagct ccagccccta aagctgcttc tttagctgct
    37981 tttactgtca tatcatagac taatccatga acagtcattt ttaatccacc agctgcacta
    38041 gaagttgcaa acatatcatt atactttata tcatctacag ataatttatt agctaaatct
    38101 ttaatagcac ctgataagcc atttcttaca tcgccacctt caaacactgt tgttggagct
    38161 tgaccttgac ccaaaaatat aggattgtta gtattaatat cgtggaaagc gtttaccact
    38221 gtagtagtac ttccaatttc agctaccaac acatctattt ttaaagaaac cttgctattt
    38281 tccattattt attactcatt tctcttcttt tttcaactaa gaaagtggct acatgtatgc
    38341 ctttgctgtt tcttccaaat ccagcatcta tgccttgttc aacagctatt tcaggtgtta
    38401 cttgtgttcc tccacacgca atcattactt tatctcttat acctttttct acacaataat
    38461 cgtgtaattt tttcatgttt ttatagtgaa tatcatcatg acttattatt gtagatgcaa
    38521 gtattgcatc tgcattcagt tcaatcgctg catctaccaa tttttctaca ggtacagaag
    38581 tccctagata gtggcattct atgccatatt tttcaatacc tccatgtttt atatctatta
    38641 tttctcttaa accaactgaa tgttcatctt ctccaaccgt agctgaaact attttcatag
    38701 gtttttcttc tatatctgct cttatttctt catcagttag taccttaggt tcttctggta
    38761 ttactaaatt gtttaaatct atatcaaacg gaactcttcc tttcacttct attctagtcc
    38821 cttcagattc atgcataact tctctactta tgacctcaat ttcttgtaag ttcatttttt
    38881 tgacaaattc caaagctgca aactctgctg ttcttttatc agtaggaagc atcattgtta
    38941 tcattacaat tccatctgca caccattcca tttcaggctt aattttagtt ccatttctgt
    39001 actcatatga ttcttttagt ctattttcta cattatcaaa atcgtcaagc tcatcaatat
    39061 atattatttt gtctggattt tcaaatgtac atccatctat taacattgat ggattatcta
    39121 tagcattttc atcatattga gctacattat tgtatccaaa gtgagcagtt acaggtgcta
    39181 aataatcttc ttctctttca taaacagtac cttcaccaac tccacctttt atttttctag
    39241 atattccatc accatttctt tctggataat ttccagaatc aacaaaaaat ccttgttcca
    39301 cagattcaaa atatccacca acttcagata tttcttccat atataataca gctctttctt
    39361 taagttctct tgctttgtct cttaattcac cgacatcttt aagttctatc atatccataa
    39421 gcccatccat accaactaaa gcttgctttg ctgtatcaca tgcttctata ttgtatatat
    39481 gccaaggtac atttctacct tcatcaggtg ttatagttga ttgtatgtca gctctagtta
    39541 atactgatgt taataagttt aatacatgag taactgttgc ttctctagtt gatgattcca
    39601 tatatttagt attcatttga gctctcatct tataatcact aaataactct ctaagtgcaa
    39661 ccgcgtaagg taagtctatt tttaaacatg gtgctggagg tgctgttggt ggaactgttg
    39721 ataagcatat attactttta tctataccta ttttttctga gaatatagag tttaaagcgt
    39781 gttgaaccat aagttcaggc attaccttcc atgcttctct agcagtagca ttagcattat
    39841 gtgctccatc aatttgagct atattggcaa aagccattat tttctttgcc tcacaagcat
    39901 ctacaaaaga ccttaccatg tttatattcc tatacagaac attatattgt gggtcttgat
    39961 gtgctccatt gactccttcc tcagcaaaca ttactgctac ttcaggacca gcaacaccac
    40021 ttacatatga atggtaatta ataggtctac caacttcttc ttctataaaa tcaagagcct
    40081 tcctttgagc tcttacttgt tttcttgtta ttggaactcc acctatacct tgtggagttc
    40141 cttctataag cccatcaaaa tgtgattgtc cagcagttct gataaccatt agatggtcag
    40201 ctccatgatg agctgccatt ctcattcttc ttatatcatc ctcaaatcta ccagaagcta
    40261 tttcagtagt aataactgga cttggttgag ggtctatatt attgaaatac ttagatgatg
    40321 gtagccctac actcttcttt aaaggttttg tacagtcttt atatttaaaa ggtcccattt
    40381 caagattttc caagtgttct ctccaaaccc aacctcttcg ttttggttta tatttatcca
    40441 aatcttttaa tatatagtct atatccaatt ttttattttc ctttaacatg attctacccc
    40501 ttctctaaat aaacatgtaa cttcatccca atattcaccc ttaactaata acaaacctgc
    40561 ttctctaacc gttatatttt tagatttagc caatttataa actacatgcc ctgctccttt
    40621 acctataaga cctctttcca taaccccttc taaaataggt tttacttcaa gagaagaaaa
    40681 tcccattctc aacaagacag acctttctat tgatggtgtt gtattctttt taccaagttc
    40741 tatcattggt tctactatct gggtagctaa actccaaaac ctttctttta actcatcatc
    40801 actcagttct tgaagatgtt ttcttctaac ttcaaaatca tcctctcttt ttttcatgaa
    40861 cattcctcca ttcgtattga tttaatcgaa ttttctgaat ttttatttta tattaaatta
    40921 aaaaacaata attactataa attatttaat acatcaacaa caaaatctct tgaacttttt
    40981 acttcttcca ttaaaaattc tatatctcga ttacttagct tatcaatatt atcaatgtga
    41041 ttattagata tacaattttt tataaatgac tttcttattt tattcatatc aatatcaaca
    41101 catttcaata attctggtct ttctggtaat attaagttta ctcctgcaat ttcttctctt
    41161 ggatttccaa attttatatc tattccattt tctcttgcaa aggtaagttg tggacatata
    41221 tgtttacctg cacccgtata ttctgtttct tgtaccacta tagctttatc ctcatctagc
    41281 tcttgagcta aagagaatgc tgctgctaaa gatgtatttc ctgctggacc tctttctata
    41341 ccttctagct gtgccaataa ttcagttgta taaaaaactt ctccttgttt tactaataca
    41401 tatctatcca tatatctaag tggtctagct gcagacctag gtacatctga cctatcaggc
    41461 catgtacagt atggtatccc aaaacctgta tgtcctgttg taaatgattt tttattaaat
    41521 tgattatcac tagccatgtg taatcctttt aaatctacac ttgctcctac tactttagta
    41581 ttaatagaac cagcttttat caatcctctt gcagttccag taagattacc accacctgca
    41641 tttgtacaaa caactatatc agggtctttt ttatactttt ctctaaattg gatagctaac
    41701 tcataaccta aagtttctac acctgcaatt ccaaatggtg aatataatga tgcgttaaaa
    41761 tagcctgttt cttctaataa aactaagaac gtataaaata actctggtcc aacagttaac
    41821 tgaacaactt ctgctccata tgcctcacat tttcgcgctt tttctatgat ttcaggttga
    41881 cctacaccat tagaatcata acattcttga actattatac attttaatcc ctgcattgcc
    41941 gcttgtgatg ctacagctgc accatagtta ccactagtag ctgctattac acctttatat
    42001 cccatttgtt tggcatgata tactgcagta gctgctcttc ttgctttaaa actaccagat
    42061 gcattcattg cttcatcttt tacaaatatt ctagctcctt taccttcttt agcacatttt
    42121 ctagctaatt tagtcaaatt tttaagctct attaaaggag tatttccaac agcatactgt
    42181 gattgaattg cttcaatatc ttgtaatgta tatcctgttt cactcatcat tttctcataa
    42241 tcaaacccta ttccctcttg ttcaaaagaa gaataatcca atccgattgc atttttcatt
    42301 atttcgttat ttcttcccat aacagcttga taactcatat ctttcattga tgttgaatta
    42361 ttcattatat acacctccaa ataatatttc tttagcttgg attcctattt ggagtaactc
    42421 tggtatacat ttaccataat catgagtata atatggattt attttaagta aattaccttt
    42481 tacaagtctg cctgtaattg ttttaacttc tactaagtcg cctatagaag catcactttg
    42541 tataaaacct ttaacccaca tttctaagga tactttctta gtatcctctg gaacttgtgg
    42601 agctctttct tctggagtca atactatatt gtgtataata acccaatcat taattttagc
    42661 atccattttt tcatcccctt attaattgac tattgcctta ctaattaatt tactgttatt
    42721 ttaaattaaa cattatttta ccaattagct aactgttatc ttactaatta gctagttgct
    42781 atcttactaa ttagcctttg attcttcttc caattcaact tctatctgat ttcttatatc
    42841 tcccattatt gctctaggta ctggtatatc caacatagtt ttaagacctg gtctagcatt
    42901 tattattaat ggaatagagt ttactatcat tgcataagta cctactcctc caggtatttc
    42961 aggatttatt tgtaaatcaa tgtttggtat accttttatt gatacatagt ctcctgtttt
    43021 aataccttct gcttctggta ttatctgttg tggatgctcc atttcaatta aaacttctcc
    43081 atttacatat ccatatccac attgtctaca accagcaaca tttccagcca atgcctctcc
    43141 gtacttagat tttctatcta ctgtagtcat tattggctct tttgtttgtt ctatcttatc
    43201 taatttccaa cctaatccat cagctatcat atttattgat tctacaaaac ctacatgacc
    43261 tgctatagtc ttatcttcta caccttttat aaattcttcc cttgttactc caacaccttg
    43321 ttccaccata acagactttc caaatggaga taaatcattt actctcttag cttttatact
    43381 agtaacttct tcacaagtac ctgaaagtgc caatactagt aaatctaata caaatcctgg
    43441 atttattcct gttccaagta tacttactcc attttccttt gcaacttcat ccattttttt
    43501 agctaaatct gcatcatcag cttgtggata tgccatttgt tctgctgttg atataacatt
    43561 tatttttcta tttaataaga aatttatttt atcaaaagcc tttttagtaa atgaatcagt
    43621 tgctaacaaa acaacatcta cacttttttc tctaaaaact tcttcataat ttttattgat
    43681 aataacttct ggtctttctc ctctttcaat tcctaaaaca tcatacatac ttttccctga
    43741 agtacttcta ctacaaacag atactatttc tataccttct ttctttagaa tcatattagc
    43801 catacctatt cccatagctc caaatcccca tattcctact cttacttttc tcatatatac
    43861 accctcctaa aaatttatat attctcaata attagttaaa gcataaatcg tgccaacttt
    43921 aaaattaaag taaatattta ttggaacgtt gaaactataa ttattttatt atgtattttc
    43981 ataaataaaa aataatattt cttatgagaa ataaaaaaaa gagcaaaata ttttgctctt
    44041 ttataataat tttgctcctc tattttgctt ttttatttta ctttgatttt gtttttttat
    44101 cttgcttatt tataatattt tgatattata tttttttatt ttatactgta aattttgcct
    44161 attcatacct aaaattgatg cagctttagt tatattgtaa gatgcctttt ctaatgattc
    44221 atatatatac ttttcttcta tctcactgat aatcttacta agtgttttgt cctccaaatc
    44281 gtttaaagaa taattgttac tctctttatt ctctttaaga gtgtaatagt cgtttagatt
    44341 aatcatactt gtttctattt gtacctcatc ttccatcata ctcatagtac aataaattat
    44401 gttttctagc tctcttatgt taccttgcca atcgtaattt tttaaaattt taatagcttc
    44461 atctgaaatt cctaccactt ttttatttaa ctttttatta tactttgaaa taaatttttt
    44521 gcacaataga ggtatgtcct cttttctatc tctaagagga ggaattttta tatgaattat
    44581 gttaagccta taatataaat cttttcgcat tttatgctcg tttaaaatta cctttggact
    44641 ttcatttgtc gttgcaataa ttcttacatc tataggtata tccttagttc ctccaaccct
    44701 tcttacataa ccttcttgta aaacccttaa tagtttagcc tgtaacataa taggcatgga
    44761 atttatctca tccaataaca atgtcccttt gttagcttgt tcaaataagc ctggcctatc
    44821 tattgctcct gtaaatcctc ccttgctagt tccaaaaaga ataccttcga atagtgattc
    44881 cggcaaagct gcacaatttt gtgctataaa tggatagttt ctcctattac ttccatagtg
    44941 aatggactgg ctaaataact ctttacccgt tccagtttca ccgtatataa atactgaagc
    45001 atcagacttg caagctttct tagatttagc tattgcttct ttaatcaaat tactttcccc
    45061 taaaatatca tcaaattcat aacccttttt ttgtctaata ctaactttat tgactaaatt
    45121 ttttttataa tttctattta gtaaattttc tatcgttgtc atattctttg atatttcaag
    45181 tgcccctaca aactcgcctt taatatcaat tggtattgta gtattaattg ctgttatctc
    45241 ttttccattt ttatccagat atttttgaat attgtctttg ataacttccc ttttttccaa
    45301 aacttctaat agtgtactcc tgtttatttt cattttgttg actatatcaa aaaatgaatt
    45361 ggttaaaata tcgtgtctgt tcattttttc cattttttgt acagaattat tgtagattat
    45421 agttttcccg tctttattaa caaaatgtac cccttcatca atattttcca atatttcatt
    45481 cattatttta aaaaatatct cttggttcaa ctatatcacc ccagtaccta aatatataaa
    45541 aacccaaaaa attaataaaa tgttgctatt gtatttatct tatcatatat ttatgatatt
    45601 ttttatgtac attatattaa tatattttta agtatattta aaattttatt tatatatctt
    45661 tcattatggt tatataca
//
LOCUS       DAGQVA010000025        44734 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.025, whole genome shotgun sequence.
ACCESSION   DAGQVA010000025 DAGQVA010000000
VERSION     DAGQVA010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44734
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.025"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..630
                     /locus_tag="MIV85_001549"
     CDS             <1..630
                     /locus_tag="MIV85_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBY2960895.1"
                     /translation="YVKEFYKTFDEAKGEYFDGFIITGAPVEQMEFEEVDYWNELEEI
                     MDYSKRKTKSTLYICWAAQASLYKYYNVKKLPLSQKCFGVFKHKVDKDSKIVDGFENE
                     FFAPHSRHTTVNIEALKENKELSIVSHSKEAGPYIITNSRDVFVMGHSEYDKYTLDKE
                     YKRDINKGDKISIPQNYYINDDPSEEPTVKWKKHSELLFRNWIKNYLIQ"
     gene            1118..1561
                     /locus_tag="MIV85_001550"
     CDS             1118..1561
                     /locus_tag="MIV85_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2960896.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            1592..3409
                     /gene="ftsH"
                     /locus_tag="MIV85_001551"
     CDS             1592..3409
                     /gene="ftsH"
                     /locus_tag="MIV85_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBY2960897.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            3587..6289
                     /locus_tag="MIV85_001552"
     CDS             3587..6289
                     /locus_tag="MIV85_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBY2960898.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            6323..7021
                     /locus_tag="MIV85_001553"
     CDS             6323..7021
                     /locus_tag="MIV85_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2960899.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            7378..8334
                     /locus_tag="MIV85_001554"
     CDS             7378..8334
                     /locus_tag="MIV85_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBY2960900.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            8511..8666
                     /locus_tag="MIV85_001555"
     CDS             8511..8666
                     /locus_tag="MIV85_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960901.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            8796..9809
                     /gene="aroF"
                     /locus_tag="MIV85_001556"
     CDS             8796..9809
                     /gene="aroF"
                     /locus_tag="MIV85_001556"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBY2960902.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            9831..10895
                     /locus_tag="MIV85_001557"
     CDS             9831..10895
                     /locus_tag="MIV85_001557"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBY2960903.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            10895..12208
                     /gene="aroA"
                     /locus_tag="MIV85_001558"
     CDS             10895..12208
                     /gene="aroA"
                     /locus_tag="MIV85_001558"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBY2960904.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELNKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            12186..13265
                     /gene="aroC"
                     /locus_tag="MIV85_001559"
     CDS             12186..13265
                     /gene="aroC"
                     /locus_tag="MIV85_001559"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBY2960905.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRVIPVIEAVTAIGIFDLMKGR"
     gene            13268..14464
                     /gene="pheA"
                     /locus_tag="MIV85_001560"
     CDS             13268..14464
                     /gene="pheA"
                     /locus_tag="MIV85_001560"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBY2960906.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRFIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            14511..15320
                     /gene="aroE"
                     /locus_tag="MIV85_001561"
     CDS             14511..15320
                     /gene="aroE"
                     /locus_tag="MIV85_001561"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBY2960907.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            15332..15865
                     /locus_tag="MIV85_001562"
     CDS             15332..15865
                     /locus_tag="MIV85_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBY2960908.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDINMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            15886..16725
                     /locus_tag="MIV85_001563"
     CDS             15886..16725
                     /locus_tag="MIV85_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBY2960909.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            16993..18474
                     /locus_tag="MIV85_001564"
     CDS             16993..18474
                     /locus_tag="MIV85_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBY2960910.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVYDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            18507..21944
                     /locus_tag="MIV85_001565"
     CDS             18507..21944
                     /locus_tag="MIV85_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBY2960911.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLITYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVELGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            21962..22708
                     /locus_tag="MIV85_001566"
     CDS             21962..22708
                     /locus_tag="MIV85_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBY2960912.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(22657..22965)
                     /locus_tag="MIV85_001567"
     CDS             complement(22657..22965)
                     /locus_tag="MIV85_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBY2960913.1"
                     /translation="MNFLKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIEKYKT
                     SYKQLLVNPNIEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            23768..27901
                     /locus_tag="MIV85_001568"
     CDS             23768..27901
                     /locus_tag="MIV85_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBY2960914.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISPPIGST
                     NLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDADNGTF
                     GFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSNVIGA
                     WWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVTGYPP
                     PQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFSEGES
                     AIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTNVFFR
                     DLIPNGLEFIPGTVTVDGVSVPGVDPNTGFSLPDIGGGTGVEVTFDVVVESIPNPNPT
                     NNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEELIYTI
                     KVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETRVIII
                     RGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNSAVPG
                     TLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGTLNSG
                     ISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISIIKVAD
                     EDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWNGSLN
                     IGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSADIEV
                     IKTSNMDTAVPEETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVTFQPW
                     NGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDETDIS
                     PLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYSIDNG
                     VTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNNNTST
                     SEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPASILSP
                     EYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPN
                     PDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTLIDNV
                     SDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNIAEVT
                     STTPDSNLNNNISRVQVEIKQFCCNDCGCKDCCCNCCCNDCGCKNCCCNCCKNDFWC"
     gene            28358..28705
                     /locus_tag="MIV85_001569"
     CDS             28358..28705
                     /locus_tag="MIV85_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBY2960915.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(28855..29904)
                     /locus_tag="MIV85_001570"
     CDS             complement(28855..29904)
                     /locus_tag="MIV85_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2960916.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            30290..31024
                     /locus_tag="MIV85_001571"
     CDS             30290..31024
                     /locus_tag="MIV85_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBY2960917.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRRSNFLGEEVIKYHKTLTTYLNALMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(31167..31658)
                     /locus_tag="MIV85_001572"
     CDS             complement(31167..31658)
                     /locus_tag="MIV85_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBY2960918.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            32007..32390
                     /locus_tag="MIV85_001573"
     CDS             32007..32390
                     /locus_tag="MIV85_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960919.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            32898..33281
                     /locus_tag="MIV85_001574"
     CDS             32898..33281
                     /locus_tag="MIV85_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBY2960920.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            33283..33633
                     /locus_tag="MIV85_001575"
     CDS             33283..33633
                     /locus_tag="MIV85_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960921.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFVDKK"
     gene            complement(33734..34192)
                     /locus_tag="MIV85_001576"
     CDS             complement(33734..34192)
                     /locus_tag="MIV85_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960922.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(34237..35025)
                     /locus_tag="MIV85_001577"
     CDS             complement(34237..35025)
                     /locus_tag="MIV85_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2960923.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(35164..35601)
                     /locus_tag="MIV85_001578"
     CDS             complement(35164..35601)
                     /locus_tag="MIV85_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HBY2960924.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            36423..36932
                     /locus_tag="MIV85_001579"
     CDS             36423..36932
                     /locus_tag="MIV85_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2960925.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            37346..37777
                     /locus_tag="MIV85_001580"
                     /pseudo
     CDS             37346..37777
                     /locus_tag="MIV85_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(37964..38157)
                     /locus_tag="MIV85_001581"
                     /pseudo
     CDS             complement(37964..38157)
                     /locus_tag="MIV85_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            38259..38765
                     /locus_tag="MIV85_001582"
     CDS             38259..38765
                     /locus_tag="MIV85_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBY2960926.1"
                     /translation="MKNEKKITVALLIVYLLILSWIILFKLQFSFSALDHIRQINLIP
                     FGGSVIANGKIDFDEIINNAIVFIPVGAYFSLLFKNKSVLKAIGSVLGISFVYEIIQF
                     IFAIGASDITDLISNTLGGIIGIALVYVLSIVLKDKTHKILNRIAIVCTVLVVAFLFM
                     LLAVNNIF"
     gene            38770..39046
                     /locus_tag="MIV85_001583"
                     /pseudo
     CDS             38770..39046
                     /locus_tag="MIV85_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4865 family protein"
     gene            39315..39887
                     /locus_tag="MIV85_001584"
                     /pseudo
     CDS             39315..39887
                     /locus_tag="MIV85_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902350.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            39990..40805
                     /locus_tag="MIV85_001585"
     CDS             39990..40805
                     /locus_tag="MIV85_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBY2960927.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALNFSNNAIIEQLDRKSIEIMDNIQKEQEKLKKIE
                     IAKKEVLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            40886..41362
                     /locus_tag="MIV85_001586"
     CDS             40886..41362
                     /locus_tag="MIV85_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBY2960928.1"
                     /translation="MTTYKVNSIGTICNNEKGAFIQLEAPYILALRALDGFSHINVLW
                     WFSDFDNTNFRSVLETEQPYKNAPEKMGIFATRSPVRPNPIALSAVEIIDIDYMSGLI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPQVPDWCSHWPHSLEESASFAWESEFNF"
     gene            41376..41939
                     /locus_tag="MIV85_001587"
     CDS             41376..41939
                     /locus_tag="MIV85_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2960929.1"
                     /translation="MSLQDYIFEKPVIETEHLILRTMNKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPELLFDKSKKSTKSFHWGIVHKQDSKVIGEIWIYLIENNRMAKVAFRL
                     SKHYQGNGLMSEVLKNVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRG
                     GKMVNTYCDYYLYGILKSDYITRWCYG"
     gene            42194..43105
                     /locus_tag="MIV85_001588"
     CDS             42194..43105
                     /locus_tag="MIV85_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2960930.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKR
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHITPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     SEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCPKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHNL
                     VTKPFMAEKYYKGNAEINYMEIWIIPV"
     gene            43183..43617
                     /locus_tag="MIV85_001589"
     CDS             43183..43617
                     /locus_tag="MIV85_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBY2960931.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            44085..44734
                     /locus_tag="MIV85_001590"
                     /pseudo
     CDS             44085..44734
                     /locus_tag="MIV85_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
BASE COUNT        17365 a         5377 c         7448 g        14544 t
ORIGIN      
        1 tatgttaaag aattttataa aacatttgat gaagccaaag gagagtattt tgatggcttt
       61 ataataacag gagctccagt tgaacaaatg gagtttgaag aagttgatta ttggaatgaa
      121 ctagaagaaa ttatggatta ttctaagaga aaaactaaat ctacattata tatatgttgg
      181 gcagctcaag caagtcttta caaatactac aatgtaaaaa aacttccact aagtcaaaaa
      241 tgttttggag tatttaagca taaggtagat aaagatagta aaatagtaga tggatttgaa
      301 aatgaatttt ttgctccaca ttcaagacat actactgtaa atattgaagc tttgaaagag
      361 aataaagagt tgagcattgt gagtcattct aaagaagctg gtccctatat aattacaaat
      421 tcaagagatg tgttcgtaat gggtcatagc gagtatgaca aatacactct tgataaagaa
      481 tataagaggg atataaataa aggagataaa atatctatac ctcaaaatta ctatattaat
      541 gatgaccctt cagaagagcc aactgtaaaa tggaaaaaac attcagaatt gttgtttaga
      601 aattggataa aaaactattt gatacaataa attttaagag tatataaatg ttaactaaaa
      661 aaatatagaa atttataggt ataaagttaa tcttaatgat actttatacc ttattttttt
      721 aaaatttgac cttataatag tagttttata ttttaagaaa atcactttag gtgtatgtag
      781 atagaggtgg ctttaatttt atatatggtg cgataatggg agactaaacc tttatagtat
      841 caataaattt gtattttaac ttttaaaaga gattaaaaag ggagaaatca gtgtaaaata
      901 tatatagatt ttttattaaa ttttattaaa aatatcctgt ataaaattaa atatcaataa
      961 gataacaaaa tttcaattga agttacaata ttgtaattga caataaatac ttaatactat
     1021 aatatttaat acattaaaca ttatagtgtt aagtatttat tacagtatgc acttcagcct
     1081 aaatttgaaa taaagtattt tcgtagggag cgtttgtatg gatgagatga gttttaagaa
     1141 agagctacta gagttgacta gagatataaa tatgaaattt acaactttat taagtgattt
     1201 ttatcagcca cttggtatta cagcagtgca agctttgatt ttatctgagt tatgtgaaca
     1261 tggagagaaa aaaataagcg atttagggaa gaacttaaac atgacaaata gtaatgtatc
     1321 agtaatctgt caaaggcttg aaaaaaatgg ctttttaaat cgcataagag atatagaaga
     1381 ccaacgaatt gtaaaagtaa aagttacaaa taaatcattg gatatacaag aacatatttc
     1441 aagtagtatt tttgatagtt attttgaaaa tatgaccagt gaaaaattgc aagatatgga
     1501 agatataata gaaggtttag agaaattaaa taaactttta acttacattg attgcaaata
     1561 acataaaaat aatttaaagg agaataaaat tatggatgaa cataaacccc aaaaaaggtc
     1621 agcactctat tattatacag ttataataat agtagtaatg tttttaaatg ctttaatatt
     1681 tccaagttta atggataaaa aaatggttga gattgactat ggaaagtttc tcacaatgtt
     1741 ggatacagga aaggttaaat ctgttgagat agaaaataat agaatagcaa taaatccatc
     1801 tagtagcaag gataagaata tatacataac tggtagaatg gatgacccag aattggtaga
     1861 tagactaaaa aatgcaaaag tagaatttac taaggttatt cctaaggaaa attcacctct
     1921 tttaagtatt ttacttacat ggataatacc tataggtatt cttatgctat ttggtaactt
     1981 aatgatgaag tctatgcaaa agcgaatggg tggtaatgct atgcaatttg gaaaaagcaa
     2041 cgccaaaatg tatgtatctg ctcaaagtgg aaaaagattt aatgatgtag ctggtcaaga
     2101 tgaggcaaaa gaagctttaa ctgaaatagt agatttctta cacaatccag aaaagtataa
     2161 aaagatagga gcacaaatgc ctaaaggagc acttttagta ggacctccag gtacaggaaa
     2221 aacactcctt gcaaaagctg tagcaggtga agcaaatgta ccatttttct caatatctgg
     2281 ttctgagttt gttgagatgt ttgtaggaat gggagcttct aggattcgtg atttatttaa
     2341 acaagcaaaa gaaaaagctc catgtatagt gtttatagat gagattgata ctattggtaa
     2401 aaagcgtgat aatggaagtg gattaggtgg aaatgatgaa cgtgaacaaa ctttaaatca
     2461 gttgttaagt gagatggatg gttttgatgg tggaattgga gtagtaatac ttgctgctac
     2521 aaatagacct gacagtcttg acaaagcatt acttcgtcca ggaagatttg atagacgtat
     2581 accagttgaa cttccagacc ttggaggacg tgaagctata ttaaaggtac atgctcaaaa
     2641 tgtaaatgta agctcagata tagattataa tgcaattgca aggtctacat caggagcatc
     2701 aggtgcagaa cttgcaaata ttgtaaacga agcagcactt ttagcagtta agtctggcag
     2761 agatatagta gaacaacagg attttgatga atctgttgaa actgtaattg ctgggtatca
     2821 acgtaaagga gctgtaattt cagataagga aaagaaaatt atagcatatc atgaaatagg
     2881 tcatgcactt gttgctgcta tgcaaaaaca ttctgcacct gtccataaga ttactataat
     2941 acctagaact tcaggagcat tgggatatac tatgcaagtt gctgaagatg agagtgtact
     3001 tatgtctaaa gaagaagcaa ttgataaaat aactactttt acaggtggtc gtgctgctga
     3061 agaggttatc tttaacactt gtacatcagg agcatcaaat gatatagaac aagctactaa
     3121 aattgcaaga gctatggtta ctcgccttgg tatgagtgaa gagtttgata tggtcgctct
     3181 tgaaactgta agcaatcaat atttaggagg agatacttct cttgcttgtt cttccgacac
     3241 tgctgctaaa atagatgaag aggtatttaa aatagtaaag gcttgtcaca aaaatgcaat
     3301 tgaaatctta gaaaataata ttgataaatt gcatgaactt gctaattatt tattagaaaa
     3361 agaaactatt acaggtgatg agtttatgga aatacttaac ttaaactaaa atgattatac
     3421 acaagataaa aatgcctatt gttaggcatt tttattttac aactaaattt tttaaattca
     3481 tatttaaatc tttacataat cttaatcatt aaaaatacat cttaactaca attttatatc
     3541 ggaattgata ttataatagt aatgaatggt gtaaggaggt tttttaatgg atagacctaa
     3601 tcctgatatt ctattagaaa aaattaaaaa tgaagaagaa aaactaagta gaggtcaatt
     3661 aaaaatattc tttggttatg cagctggagt aggaaaaacc tactctatgt tggaatctgc
     3721 acaaaattta aaaaaagtgg gtgtagatgt agtagttgga tatattgaac cacacactag
     3781 accagaaaca ttggctttac ttgatggctt ggaaattctt cctgtaaagg agatagaata
     3841 taaatctata aaactaaaag aatttgattt agatgctgct ttagcaagaa aaccagaagt
     3901 tatattagta gatgaatttg cccattctaa tgttgctggg ttaaggcata caaaaagatg
     3961 gcaagatata gaagaattgc tgttagcagg cataaatgtc tacactactg taaatgtaca
     4021 acatttagaa agtctaaatg acattgttga gataattaca aacgtatcag ttaaagagac
     4081 tataccagat aagtttttgg atacaaatac acagttagaa cttatagatg ttgaacctga
     4141 tgtacttctt gaaaggttca atgaaggtaa gatatataag aaagaacaag ctactagagc
     4201 aaaaaataat ttttttataa aagataacct ggttgcactt agagaaatcg cacttagaaa
     4261 aactgcagag agagttaata aagaagttca aatgaccaga ctatcaaagg gtgatgtaac
     4321 tgtaatacct acatcagata cacttcttgc atgtataagt ccatctccat cttcagcaaa
     4381 agttattaga actgcatcca gaatatcaga cagtacattt gcaaaatgga tagctttata
     4441 tgttgaaact ccaaacacag caagacttcc atttgatgaa caaaaacaac tacaaaataa
     4501 cctaaaatta gctaagaaat taggtggaga aataattgtt ttacatggtg aaaatataat
     4561 agagcaaata cttagaattg caaagctgag aaatgtaaca aaaattgtaa taggtagaaa
     4621 tcattcaagt aataaaagat ttagtaaaag atttaaaaaa gatatagttg acaaattaat
     4681 tgatgaagtt gattatatag atatacatat aattccatat aaatttgcct cagatgttaa
     4741 atacaaacct aaaaaggata aatcatcaat aaaatctaaa tttaaaatta gcaaagttga
     4801 ttttataaaa cttatattta ttactttgat gataagtatt ttagcatatg cagtacaaag
     4861 catgggattt ataagagaaa atatattgtt aatatatatg ttgggtgtag ttttagtttc
     4921 tatgtggact aaagggtata gtacaggtat aataagttct gtatttaata tagttctttt
     4981 aaattatttt ttcacagcac cattatatac attatctata gcagattcaa actatatagt
     5041 aacactggtt gtattctcaa tagtaggtat aataactagc actcttacgt ctaagataca
     5101 gcatgaagca gaaactgctg ctaaaagaga agaaaataca aaaatgatat atcaaataat
     5161 taagggattt ttaagattat caaataaaga tgatatagta aacaaaggta tagaactttt
     5221 gtctcttagc ttaagtagag atgtaatttg ttatttaaat gtagataagc ataataaatc
     5281 aaagctttac aaaaaaaata ctaataataa ggataaaaat gatttggata gtgaagatga
     5341 aaaagctgtt gcaagttggg ttttatccaa ttcaacagta gcaggaaatg acacggatac
     5401 acttcctggt tcaaagggat actatatacc aattgtagga atgaatttaa ctttaggagt
     5461 agtgggaata tcatgtattg attcaaaatt ggatacagaa gatataagct taattgaaac
     5521 aataattgct caaatggcaa tagcgcttga tagagaaatc ttgtcagaag ctaaagaaaa
     5581 taccaatctt gagattgaaa gggaaagatt aagaagtaat cttttaagag cagtttcgca
     5641 tgaccttaga actccactag caggaatatc tggtgcagta agtacaatta taaaaaacaa
     5701 gggtactata ggtcaagata taatagatga attacttagt ggtgtatatg aagatactca
     5761 gtggttaata agacttgttg aaaatttact tagtatgacc aagatagatg aagggaaatt
     5821 ggaagttaaa aaacattctg aactggttga ggaaattata tcagaagcgt tacaaaaaat
     5881 aaaaaaaaga attgaaaatg cacttataga tattaatata ccagaacaga tattatttgt
     5941 tcctatggat gcaaaattaa tagaacaagt tttaattaat ttaatagata attctttgaa
     6001 atattcaaag gaagattgta agatagagat aaatgtatat gagaaagatg attatgtttg
     6061 gtttgaagta tctgataatg gtcctggtat atcaaaggaa cttaaaaagc atatctttga
     6121 cagatttttt actggagaag aaggagctaa agattccaga aagggtgttg gacttggatt
     6181 atcaatttgt aaatctataa ttcaagctca taaaggtgaa attatggtag aaaacaataa
     6241 agataagggt tcaactttta agtttagttt gcctaaggaa aatgaatagt tttaaatttt
     6301 aaaattagtt ttggaggaag aaatgagtaa aaaacttata ttgttagtag aggatgataa
     6361 gacaataaga aaatttatat ctactgcact tttaacacag gattatgatg tcaaggaggc
     6421 tataactgga aaagaaggta tatctatagc tgtctcatat tctccagatg ttgttctttt
     6481 agatttaggc ttagaagata tggatggaat agaggtaata aaagctatca gacaattttc
     6541 aaatatacca ataattgtag tttcagctag agagcaagat agagacaagg tagaagtatt
     6601 tgatgcaggg gcagatgatt acttaacaaa accattctcc atagtagagt tattagcaag
     6661 agtaagagta gcatttagac attcacaagt agaagctcaa caaaaagatg atgttaaatc
     6721 tacgtttgaa gtagataaat tattgattga ttttgataaa agaaaagtta ttgttgatga
     6781 tgttgaagtc catttgacac ctattgaata taatattctt tcattacttg caaagtatca
     6841 tggaaaagtg cttactcata attttataat aaaagaaata tggggtagtg ttatagggaa
     6901 tgagactaag tctttaaggg tctttatggc aacgttaaga cgaaaaatag aaaaacaacc
     6961 tgcaaaccca agatatataa ttacagaagt tggtgtagga tacagattaa atgatgaata
     7021 gttgtaatat attaattatt agattatgtg cttattaata tatattaaaa ttatatagtt
     7081 tagttaaaat aagaatgaag tgtatgtgct tgttgtcagt ttagcacatg cattttattt
     7141 tttagctttt ttagtatcaa taatttttta gtatcaataa tatgaaatat gttttaaaat
     7201 aagtatatag tgtaatctgt aataaaaact ttggttaaat aataaatgta tttaacactt
     7261 accttataat aaatttaata taaatattaa ataataatta ttaaaatagt gtaaaataat
     7321 tacagtaagg attataaaaa atttttagaa tgtaaattga aatttaggag tagatgtatg
     7381 tatatactga atttaaatac aagagagact attgaagatt ttagagataa attttatgta
     7441 gcagaaaatt cttatcttat attaagtgct ccaaaaaatt taaaattgct taaggaaact
     7501 ttggatatag atgaaataac ttttaatgat tgtcttaaat ttgatgaaat aaccaaactt
     7561 gatttatttg ataattacga ttttttaagc ctaaatacat ttgaactaag agatggagaa
     7621 gctgttatag aagaggtaaa tatgtattta tcagataatt ttatattggt tgtagtgaat
     7681 gaagaacact ttttatttga atttgtaaaa aatattattt tgaagaactc tcaacttgaa
     7741 aaaaatccag ttattaatct atttaagata aactacttga ttcttagaga agttataaaa
     7801 aatggttttg agtctttgga aaaagttgaa gagttaattc ttcaaataga agatgaaatg
     7861 atggacaaca ttaataagaa tcatgtatct agaataagtg atgtaagagg attaacaaga
     7921 attatagtta agaatactag acctcttttg tatattgggg atagaatagt taaggaaaat
     7981 ataagatatt taaaatattc aaatgtaaaa aaatataatt tagaaaattt tcaaggtata
     8041 gattttggaa ttgacaaatt atacaatttc gcattgtcaa cacgagagtt agcagataaa
     8101 ttattagata tttattcttc cagagtaggt gagaaaacaa ataacttaat tacaaaatta
     8161 accttgttaa cagccatatc agcaccactt acaattataa ctggtatata tggaatgaac
     8221 tttagatata tgccagaatt aaactggatt tatggatatc cagcaacttt attttttatg
     8281 ctatgtataa tttttgttgg aattataata tttaaaataa aaaaattatt gtaaattaca
     8341 gatgatgttt aattgatttt ataaaaatac atcaattgag aagctgattt aagtaaataa
     8401 aaaaatattt taaattgaaa atatttatag aaaatattga caattatatt ttctttgtta
     8461 taattattaa acaagaagaa taataaatta taaaaatgga ggataatact atgaaaggaa
     8521 tattaaaaga actaacagca aaactttata gcttttttta ctttatgttc tggggctttt
     8581 attttagcgc tggctatttc ttttacaaaa atatatgtac ttcctttctg gtgaggcctt
     8641 attttagtga ttttgagcat aagtaaattt tataaaaatg attattttat atatttatat
     8701 aagatttagt gcttgataga ttattttaga gaactcatta gtgagttctc ttttttattt
     8761 taaatataaa attataatat tgggaggtag taaaaatgat agtagtatta aaaatgggag
     8821 cagataaaaa tgaagttaaa aaattaattg aggctattgg gagagaagga gtagaagtta
     8881 atcccataga tggaacagaa ttaactgttt taggtttagt tggagatact agtaaaatag
     8941 atgccaaaag aatagaagca aataaggtag ttgaaaaagt tatgcatgtg gtagagcctt
     9001 ttaaaaaggc caatagaaaa tttcatccag aaccttcaat cataaatgtt aatggaatgg
     9061 aaattggttc aaagaaaatt gctatgatag ctgggccttg ttctgttgaa acagaagacc
     9121 aaatagtatc tatagctaaa gatgtgaaaa aatcaggtgc aggatttttg agaggtggag
     9181 cattcaaacc aagaacatca ccatacgctt tccaaggatt gaaatatgat ggattggatt
     9241 tattaaaaaa agcaaaagaa aaaacagggc ttcctatagt tacagaaata atgtcaacac
     9301 aagatataga tatatttgaa gaaaatgtag atgtaattca agttggagct agaaacatgc
     9361 aaaactttga tttattaaaa gaattaggta aaacaaataa aacaatactt ttaaaaagag
     9421 gattatctgc tacaattgaa gagtggctaa tgtcagcaga gtatataatg gctggaggaa
     9481 atgaaaatgt agttctttgt gaaagaggta taagaacttt tgaaacatat actagaaata
     9541 ctttggattt aagtgcaatt ttagctgtga agaaacttag tcatttacca gttatagttg
     9601 acccaagtca tgcagcaggt aaatcatgga tggttgactc tttatctaag gcagcaattg
     9661 cagttggagc agatggtcta ataatcgaag ttcataatga cccagcacat gcactttgtg
     9721 atggaaaaca atcgattaag ccaaatgaat atgatgaatt gataagtgaa ttaaagacta
     9781 tcgcatcagc agttggtaga gaaatataat ctataaaagg atggttaaac gtggaagaaa
     9841 aactattagt aaatttaaaa gaaaatagct acaatatatt tattaaaaaa aatatactaa
     9901 agaatatagg agaagaaata aaaaaaatat attttggaaa taagattttt attgtaactg
     9961 atgaaaatat agcaaaatta tacttggata aagtaaaaaa taatttaagt gaatctggat
    10021 ttgaaattaa atctttaata ttaaaatctg gtgaagaaac aaaatcattt aatactcttc
    10081 ctaaaatata cgatagttta cttgacttta agttaactag aaaagatttg attattactt
    10141 taggaggagg ggtaataggt gatttaggtg gatttgcagc agcaactttt ttaagaggta
    10201 taagttttat tcaaattcca acatctttat tagcacaagt tgatagttct gtaggtggaa
    10261 aagttggagt tgaccttgag agaggcaaaa acttagtggg aagcttttac caaccaaagg
    10321 ctgtgtttat cgacccaaat gtattattat cacttccaga aaaattctat agagatggaa
    10381 tggcagaagt tataaaatat ggatgtataa aagacaaaac ttttttcaat aaacttttaa
    10441 gtttaaaaaa tagagaagaa gtaatgcaac atatagaata cattatacat aaatgttgct
    10501 ttattaaaaa aactgtagtt gaagctgatg aaaaagactt tggagataga atgcttctaa
    10561 actttggcca tacattaggt catgctattg agaaatacta caattttacg ggttataccc
    10621 atggagaagc tgttgccata ggaatgtata agataacttt agaaagtgaa aagataggaa
    10681 ttacaaaaaa agggacatca gaacttataa aatcaatttt aatgaattat aatttgcctt
    10741 atgagattga attaagagat aataaatcta tagtagatgc tatatctctt gataaaaaaa
    10801 atctaggtga tacattaaaa ataatacttt taaaagatat tggagagagt attatatata
    10861 atactacttc taaatttttt caggaggtaa gataatggga agtctaaaaa tatatccaag
    10921 taaattatct ggagatgtaa aaataccacc atcaaaaagt atggcacata gggcagttat
    10981 ttgttcatct ctaagcaatg gaaaaagtag aatttctaat atagattttt ctgatgatat
    11041 aatagctact ataagagcaa tgacatcatt aggagctatt atagaaaaga aagaagatat
    11101 tttagaaatt tcgggaattt tttctaaaga aggtatttta aatagagaga atcagttgaa
    11161 tcaacctaaa ttgacaatag attgtaatga atcaggctct acattgagat ttttagtacc
    11221 tatatcttta gcatttgatg gtgtaaaaag gtttataggt agaggaaatc ttggaaaaag
    11281 accacttgat acttattatg agatatttga cagacagaat ataaaatata gttacaaaga
    11341 aaatcagtta gatttgatta tatcaggtaa gcttaaacca gatgaattta gagtaaaagg
    11401 aaatataagt tctcagttta tcacaggttt actgtttata ttgcctacgc tagagagtga
    11461 ttcaaagata ataattacta ctgagctaga atctaaagga tatttagatt taactctttc
    11521 aacgataaaa gattttgggg tagaaattat aaacaataac tataaagaat ttattataaa
    11581 aggaaatcaa acgtataaag cgagagatta taaagtagaa ggagattatt ctcaaggagc
    11641 attttattta tcagcagatg ctataggaga agatattagc atattagacc ttaaagaaga
    11701 ttctcttcaa ggggatagtg aagtagttga aattttatct aggatgggaa tggaaatatt
    11761 aagagaaggc aacaaaataa aaggaataac aaatggttta aatggtactt tgatagatgc
    11821 atctcaatgc ccagatataa tacctgtatt atctgtagta gcatccttaa gtatagggag
    11881 gactacaata attaatgctg gtaggcttag aattaaagaa tgtgatagac ttcatgcaat
    11941 aaatgttgag ttaaataaac ttggagcaaa tatagaggag aaagaggata gtttgataat
    12001 cgaaggagta agcaagttaa atggtggagt agaggtgtgg agtcacaaag accatagaat
    12061 tgctatgaca cttgcaattg cttcttgtag atgtgataaa ccaataatat taaaagattt
    12121 tgagtgtgta tcaaaatctt atccacattt ttttaaagat tttaagatgt taggaggtcg
    12181 aattgatgag tggaatatgg ggaaataatt taaaagtatc aatttttgga gaatctcatg
    12241 gaaatgctat aggtataaat atagatggtc ttccttcggg gattgaactt gaccttgata
    12301 atattgataa agaaatgaag agaagagcac ctggaaaaaa ttctatatct acttcaagaa
    12361 atgaaagtga tataccagaa attctaagtg gatattttaa tggaagaact acaggaacgc
    12421 cattatgtgc aatcataaga aatagtgata ctcgttcaaa agattatgga gagcttaaaa
    12481 acttaatgag accaggacat gcagatttca caggtaatgt gagatattct ggatttaatg
    12541 actatagagg tggaggtcat ttttcaggta ggataacagc tccattagta ttttgtgggg
    12601 ctatatgtaa acaaatttta tcacaaaaag gaatagagat aggagcacac ataaaaaaaa
    12661 ttaaaaatat agaagatatg agttttgatt atgtaaatat ttcaaaacaa cagttatcaa
    12721 atttgcaaac tttggaacta cctttacttg atttatcaaa ggaagaagcc atgaaaaata
    12781 cgattataga tgcaaaaaat caaggagatt cagttggtgg tataattgag tgtgcagtag
    12841 taggtattaa tgtagggctt ggaaatccat tttttgactc tgttgaatct actttatcac
    12901 atttattgtt ttctgttcct gctgtaaaag gtgtagagtt tggtttaggt tttgaacttg
    12961 cagatatgta tggctctcaa agtaatgatg aaatgtatta tgaaggaaat caagttaaga
    13021 gcaaaacaaa taacaatgga ggaattatag gagggattac tactggaatg ccaataattt
    13081 tcaaagtggc aattaagcca actccatcaa ttagcagaca acaaaacaca gttaatataa
    13141 aagataaaaa ggacgatatt ttatatatta aaggcagaca tgacccttgt atagttcaaa
    13201 gggttatacc tgtaatagaa gcagtaacag ccattggaat ttttgatttg atgaaaggac
    13261 gataataatg gaggatttaa cgagatatag aaatgagatt gacaatatag ataaagagct
    13321 tattcaatta tttgaaaaga gaatgaatac agttcttgaa attgccagac ataaaatgaa
    13381 aaataacact actatacttc aaaaagatag agaagaaaaa gtactaagta gagccgtaga
    13441 taatttagat aataaagcat attcacaaga aacggtacag ttttttaatt ctataatgga
    13501 aattagtaga ggattacaaa aaagatttat agataatgat ggtgagcaga aaatcgagtt
    13561 tagtttagat tcatcaaata agaattttga tttgtcaaat gtaaataaat ataagtcttt
    13621 aaaagatgaa ttaaataaaa aaaatatcct agtaggcttt cctggaaaat caggttcatt
    13681 tacagaagaa gcactaaata aattcttcaa caaaaaaata tcaaaaaaac aatttaaaga
    13741 atttgaagat gttttcatag cacttaaaaa taaagaaata aactatggaa taatccccat
    13801 agaaaattca tctacaggag ctatctctga aacttatgac cttttgagaa agtacggttt
    13861 ttatatagtt ggagaagaat gtataaaaat agaccaaaat ttaataggga taaaagacac
    13921 aaagcttgaa gatataaaag aaatatattc tcatccacaa ggtataggac aatgtagtga
    13981 atttttaaaa caaaatagta catggaaatt gatacccttt aataacacag caacaagtgc
    14041 agaacttgta agaaaacttc aagataaaac aaaagcagca attgcaagca aaaaagctgc
    14101 aagtatttat ggattagaaa taataagtcc ttgtataaat gatatagcaa acaactatac
    14161 aagatttgta gtaatcagta atcaaataca cattgaagaa gaatcaaaca aaatgagtgt
    14221 agtattttct gttgaacatg aagcaggaaa actttataaa gtacttggat actttgctaa
    14281 aaataatata aatatgacaa aaatagaatc aagacctatg aaaaatgcct catggagata
    14341 tttcttttat atagattttg agtgttctat atacaatgct aaagtgtacg atttattaga
    14401 attgatagaa cataatacag catattttaa atttatggga gtatataaaa ataaaactga
    14461 atagataaga taaattttta tttaatttat aattattagg aggtgtaagt atgaattttt
    14521 tcggtctagt aggtgaaaaa ctctctcaca gtgtttcacc tcaaatccac aagagagtat
    14581 tcgagatatt gaatattgaa agtgcttata aaaactttga aatttcaaaa gaagatatat
    14641 ctaagctaga cggtgctata aaattattag gaatacaagg ggtaaatgtt actgtaccat
    14701 ataaggagcg tattatgaaa tatcttgatt ttatatcacc agaggcaaaa cgtataggag
    14761 cagttaatac aattttactc agagaaaata tgttatatgg ttacaataca gattactttg
    14821 gtcttgatag tatgtttaaa atggctaata ttgatgttca aggaaaagta gcagttatat
    14881 taggaactgg aggtgcttct aaagctgctc ttacatattt tattgattct ggtatagaaa
    14941 agctttatgt ttcaactaga aaaaaggatg ataaaaaatt attaaatagt aaagctatat
    15001 taatagatta tgaagaactt aaacatataa aaggagatat aatattaaat gctacaccag
    15061 taggtatgta ccctaatgta ggaatttcac cagtgtcaaa atctattata caaaattttg
    15121 atatattaat agatttaatt tacaatcctg gagaaacaga gtttttaaga attggtaata
    15181 gtatgggtaa aaaaacttgt gatggattat atatgctggt ggggcaagca ataaaatctc
    15241 aggaaatttg gcaagatact aaaatagata atagtatttt agatgttata tataatgaac
    15301 taaaattaga atttttgtaa gggagattgt tatgataaat aaaacaaaag aaaaattgat
    15361 attaataggt atgccaggta gtggaaaaac tacaattggt aaacttttgg ccaaagaata
    15421 taattgtagt ttctgtgata tggatgatta tataattcaa atatctcaaa aaagtatagc
    15481 agagttgttt tcagaaggag aagatatctt taggaactat gagactcaag catgtagaga
    15541 actttctata agtgataaaa cagtgatatc tacaggtgga ggtgtaataa aaaaggatat
    15601 taatatggaa atactaaaag aaacaggtat aataattttt attgatagac ctatacaaaa
    15661 gattttggaa gatataaata ttaattcaag accattatta aaaaacggaa aagatagatt
    15721 gtataatctt tacaatgaga gaataaatct ttataaaaaa ttttcagata tagagatttt
    15781 aaatgataaa tcattaaata atgctgtata taatattaca aatgcagtca gtgaaaattt
    15841 taaatttgac tttaaagaaa aataatctag ggggaaataa aaataatgaa tattgttatt
    15901 gtaggactag gagttatagg aggctctttt gctaaagcat taaaaaaagc tggatatgaa
    15961 aatgtatttg gagtagatgt agatttagaa actttaaaaa aagcagaaaa agcaaaaatc
    16021 ataaaaaaag gatgtactac aggtaaagag ttatttaaaa aagctgattt aattatatta
    16081 tctatatatc ctagattagt tgtagatttt ctaaataata ataaaaactt ttttaaaaaa
    16141 gggactataa ttactgatac tacaggaata aaagaaacac ttatcaatga tgtgttgcaa
    16201 attattccag atgatataga ttttatattt ggacatccaa tggcaggtag ggaaaaaaag
    16261 ggtattgatt ttgcaagtga acaagttttt aatggcgcaa attatataat tactccaact
    16321 ggcagaaaca acataaaaaa tttagagtta gttgaaaatt taattttaga gattggattt
    16381 aaaagagtaa aaaagttaac ttcacaaaaa catgatgaga ttatagcttt tacttctcag
    16441 ttacctcatg ttatggcagt tgctcttata aatagtgatg aagaaggtag agatacgggt
    16501 aaatttattg gagatagtta tagagattta actagaattg caaatatgaa tgaagactta
    16561 tggagtgaac tttttttagg aaatagagat aatttactaa aagttataga aaactttgaa
    16621 tcagaagtaa atttagtaaa agaagctata tttaacaatg ataaaaataa attaatagag
    16681 tattttaaaa aatcatcaat aagaagagaa gctttagaaa aataaatatt aatatttaag
    16741 ctatatatag atgggtataa atataagcga tagtgtattt aattgtatta ataaatatgg
    16801 attcaatata attaaatatg ctattgatat atttgtaccc ttaactattg ttatctttta
    16861 gatgataatg atatttattt aaatactctt tattaacaat ttataaaact taattgtaaa
    16921 aaatacttat taatagtaaa ataaagtgaa tcaattatat tataattgct aaagagagtg
    16981 aggtgtagct atttgaaaaa aaatagatta atagcaaaga atatatcaat agcatttata
    17041 gtactattct tttttagtgt atttacattc ttttatgtag gtaatattaa tagagtgtta
    17101 gaatatgaaa caaatgacat aataacagtt acaattgctg gatggattat actttcattt
    17161 ttatttttag gtattataat ttacatatta tattcaaaag caaatagtca aaaaactata
    17221 gaaaaagtag catatacgga ttttgtaaca ggttattcca actggagaaa gtttgaatta
    17281 gatgttacaa atttattaaa gaaaacatca caaaataata aatatgcaat ggtcatattc
    17341 gatattgata aatttaaagc aattaatgat atatatggcc ataaaaaggg aaatttaata
    17401 ttaaaagata ttgcagatac tttaaatgaa ttgactgata tcaatgaaac ttttgctcgt
    17461 gtaagtgctg ataatttcaa tatattatta acatataaca aaaaagagga tataataaat
    17521 attatcaaaa agattatggc aaataatgaa cttgtaaact tatcttttgg aatttatgaa
    17581 atcaaagata aggatttatc tgtaagtgta tatagtgata gagcttcact tgcaaaatca
    17641 tcaataaaaa ataatagtga tgtaaatttt gcatttttta atgacaaatt aagagagaaa
    17701 ttattatttg aagataagat agaaaaagaa atggaatatg ctcttgaaag tgggcaattc
    17761 gtaatgtatt tacaaccaaa atacaatatt aaattagata aattttgtgg aagtgaagcc
    17821 ctagtcagat ggcaatatac agaaaaagag gtcatatatc caggtgattt tattcctata
    17881 tttgaaaaaa atggatttat tagaaagatt gatatgtaca tattagaaca agcttgtaaa
    17941 gaaatccggt ctttatttga taaaggaatt tcacctttac ctatatctgt aaacttctca
    18001 agagttgatt tttttaaaaa agattttatt gaaaacatag taaatatatg tgatagatat
    18061 aaaataccat atagtttaat agaaattgaa attactgaat ctagtatgtt tggagatact
    18121 gatactctat ttaatgttag tagaaaccta caggatattg gctttatagt tgcaatggat
    18181 gattttggct ctggatattc ttctgtaaat atgcttaaaa atataccatt aaatgtaata
    18241 aaattagata gaggattttt tgtttatgat aaagatgttg ataagagtca aattgttata
    18301 aaaagcatag tttctctcat taagcaatta ggaataaggg ttgttgctga aggaattgaa
    18361 acaagaagtc aaatagaaat gttaaaaaaa gcaaattgtg atattgttca aggatattat
    18421 ttttcaaaac cattaccaat taaagaattt gaaaaattag tctataaaat atagtcagcg
    18481 agtcttaaat gggaggtggt gattaagtga taagagcaaa atcgttaaaa aatgtactga
    18541 gtattgtttt aatattttta tttacaataa tttctttttc tgattttgca tttaaaacta
    18601 atgtccagga agaagaaaat agtaaaatta atttaagaga aatatcccta caaagttcca
    18661 atgctataaa aataaaatta gatagttctc tatcctttat taaaagtgtg gcaaatatgg
    18721 tttcttattt taatactata gataactcaa aaatagttcc attattagct aatatatcaa
    18781 aagaatctga ctttcaaaga atctctattg tatctcctga tggaataagt cataccagtg
    18841 atggcaaaat tatcaatgtg tcaaagtatc agtattttaa gaaagctatt aaaggagaaa
    18901 gtaatatatc tgaagttgtg aaatctccaa ttgatggaaa agatactttt gttatagcta
    18961 ctcctgtatt taataagaat aacaaaataa ttggtgtttt atacggttct tactacaatg
    19021 ataaattagc tgaatttata gatataacaa gttttaatag tgaagggtac atagatatat
    19081 ttgaatctag tggtcaattt gttttaaaat cttcacatac aaacaaactg attaagtcaa
    19141 gtagtaacat atatgatata tttaaaaaag cttcttttga tgatggttat agctataaaa
    19201 aaatatatga agatacaaaa aataacaaga gtggctttac ctcatatgaa tacaaaggag
    19261 aaaatcgtta tgctacttat acacccattg gtgtaaatga ctggtatgta atttctgtga
    19321 taccacaata tactgtaaga agaaacattg ataaaataaa tcaattagca ttttctctta
    19381 ttttcaaggt attcttattg tttattatgc ttataacata tattatttat aaaaacaata
    19441 aatctcagaa agatatacta aaagctaaca aagaaatctc atctattaca aatagcattc
    19501 ctggaggagt acaaaagtgt accctgggtg aaacatgcaa tattaatttt ttaagtgatg
    19561 gatttataga gttgtttggt tatacaagag aagaaataaa aacattgttt aataatgatt
    19621 tttatagttt aatacataaa gatgatgttg aaagaataaa aaaagaaatt tttaaacaac
    19681 tttacaaaaa taaaactgtt gaattagaat ataggattat aacaaaaaat ggtaatacag
    19741 tatgggtttt agataaaggg gagcttataa cagaacctga tggaaaagaa tatttttgtt
    19801 gtgtaactgt agatattact agaacaaaac aattagaaca agagatggaa caaaaaaatc
    19861 tagaacttga aatgatatca gaaaatgttt taggtggtat aattataaca gaatttaatg
    19921 atgattttac tataaaatac gctaactctg gttatctttc aatgattgga tatacacgtg
    19981 aacaattaga aaatgaactt aaatacaaag cttgtaatct tgttttttat gaagatagaa
    20041 agaaggctct tgaaagtata caacatcaat taaacacaaa aggaatagct gtatatcaac
    20101 atagaataag aagaagagat ggtaatatta tttgggtttc tataaaagga aggcttattg
    20161 ttgatgatga tggtattgaa aaaggtattt ggattctaaa tgatataaca gatttaaaaa
    20221 atgcagaaca aaaacttaaa ataaatgaag aaagatttag aattgcatta aagcaaacat
    20281 caaacactat atttgagtat gatataaaaa caaagtcact tttaaatact agtaaagagc
    20341 ttgataaata taatatttat aaaattacta aaaatgttcc atattctcta gtagaattag
    20401 gagttattca taaagatttt agtgatgatt ttataaatat gtatgaaaat gtaataaatg
    20461 gagcaaaaaa agcaagttgt gtagttaaga tgaaacttcc agatgaaaat tatatatgga
    20521 ataaagttac cttgactacg atttttgatg aagatggtaa tcctgtaaga gcaattggta
    20581 tacaggaaga tataagcaaa caaaaggaag cagagataag atacaatcaa gaaggtaagt
    20641 atcattcagc tatattgtcg gaagcaatga taacttatga aataaatgta tcaaaggata
    20701 cttttatcaa aggaaatgaa agttggcaaa aaccatttgg aattaagcct gacaataact
    20761 attctcaaat ggtaaaaact atagcaaata gtattgtaca taaagacaat aaagaaacat
    20821 ttttaaatac atttttatgt gaaaacttat tggatgcata taaaaataat gtgactgaaa
    20881 taaaattaga atatcgaaga atgaatcaag aaaataaaat gatttgggtc atttgtacaa
    20941 tgcacttaat aaaagattct attacgaacg atataaaagc acttgcttat gttaaagata
    21001 ttgacaagca aaaaaatgaa gaaattagat taaaattaaa agctgaaaga gatactctta
    21061 caggattata taataaaggt actacagaaa aattgattaa tgatttcttg aactctgagg
    21121 aagcaagctt aggaatgcat gcatttttaa ttgttgatat agataatttt aaatctgtga
    21181 atgataattt aggacatgta tttggagata aagtattatt tgaagtttct aaaaacctaa
    21241 aacctatatt tagaaaagat gatatagtag gtagaattgg tggagatgaa tttatagtat
    21301 tcttaaaaaa tattcagtct tttgagaata tcaaaaagaa agcagaaaaa atatgcgata
    21361 tatttagaaa ttcttataca gaaaataaaa agacatataa aatatctgga acagttggaa
    21421 tttcatttgt accagaacat ggaactgtat ttgaagaact ttataaaaaa gcagacatag
    21481 cactttatta tgcaaagagc aaaggaaaag ataagtatgc actttataat gattgtatct
    21541 accaaaatga acttgaaaat aatataagtg ataataatat aaagttagca gataaatgtg
    21601 agaaatccaa accagtactt aaagaaattc ttgattctat tgataattat atctatatag
    21661 tgaatccaaa tacttatgaa cttctttttg tcaataataa ggtgtctcgt ttggatttag
    21721 agataaaatt aggagaaacc tgttataaat cactattaaa atctgataga ccatgtaata
    21781 attgccctct taacggatta gaagaaaata agcattcaaa attcaaaata gagacaaata
    21841 catttggtaa aaatatcagt atagcaagtt ggattaattg catagatgga gaatacaact
    21901 gtcttataga gtgtatagat tcttctttat acaaaaataa ataaaaaagg actatgaaga
    21961 tatgttaaat agtataactt tgatacttgg tataatattt acaatttact atttttatct
    22021 caaaatagtt tttggaggaa tttcatttag tgagattttc ttagttgtag gaattgtact
    22081 aattatctat caaatattta agaaaaaaat taaagaaaag aaggtttttt atagggtgtt
    22141 aaaaataata atcagcattt ttttaatagt atttgtagtt actgagagtc taattatttt
    22201 ttatcccaaa aatagtttag aatcaaaaag tgattatctc ttaattttag gagcttctgt
    22261 aaaaaagact acaccaagta caaccctgaa gggtaggtta gacactgcat tgaaatacct
    22321 aaaaattaat gataattgtt atgtggtagt atctggtggt aaaggaagtg gagaaaaaat
    22381 aactgaggca aaagctatga aagattatct tataaaaaat ggtatagata aaaataggat
    22441 aatagaagag gataaatcca cgaatactta tgagaatttt aaatattcaa aattgaagat
    22501 agaagaacat agtcaaagaa aactaagcga tttaaaagta aaaatagtaa caacagattt
    22561 tcatgttctc agaagtaaaa tattagcata tagaaatgga tataaaaata cgtcttttta
    22621 tgctagtaaa tcaaaacttt catttgtacc aacttactat acaagagaat tttttgcatt
    22681 atggaaaaca atcatttttg atagataata aataaaaaga ctagatataa actcatatct
    22741 agtcttttct attcccttaa ttctaatcca ttttccaact ttacttgttg tagaaatttc
    22801 aatattggga tttacaagta attgcttata agaagtttta tatttttcga ttccaaaata
    22861 taattttcct tcataatcca ttataaatcc aaatggtctt actcttggtt tattatcttc
    22921 aactgtagca aaatagaatg ttgagttttc ttttaaaaaa ttcattattt tttcatgatt
    22981 aaatcctctt tgtatcttat actaatataa tgaatataaa taaaatattc attatactta
    23041 atataaatcg atataaaaac aattacaata ttatattgat tattcgaaat tatatataaa
    23101 attcagaaaa aattttagtt tacataacaa aaataaagtc aactaaaatt attgatttta
    23161 gattaaagta ccggattaag catttaagta gattttaagc ttgatttgat tggaaaggta
    23221 caaactatca ccgaaaaaaa ttaaacccat ttaaaaagca atataaaagc ttgttatttt
    23281 tgagaaaaat agaccctcta aactcaatta gattaaaaat aaaatacaga aaattatatc
    23341 tctaaatatc ttaaataatt aagtttaaat tttacgatat tttgtttgat tatttataat
    23401 ataaaagcat actcttaatc ttcaaaattt aaaaagagta aaaaataaca aaaaaatcac
    23461 tgacatttca ctgacaaatt gtaattttgt tattataaat acattgaaaa tacttgatta
    23521 ttgaaaaatg gcataaaata atacatttta tgccatttac tattatttga tagtttttaa
    23581 cttatgacat aagatatttt ttaacacata caataaaata taaaaaaatt gatattgcaa
    23641 ataaaaaaaa tacatattag atgttataga aaaaaagcgc acttataggc ttaaaatgtc
    23701 acataaaaga gttttaaaga ataatatatt atgaacacaa attttgtaat cacaaaggag
    23761 tgataatatg gcaacagtat caggacaaat agtttttgat agaaatagaa gtgctaccat
    23821 tgattctgga gactcaggaa tagccaatat accagttgta ttacaagata tagcaactgg
    23881 agttagactt gtggttctca cagatgcatc aggaaattat gtttttacta atgttccaaa
    23941 tggtaactat agaattgtag aagcttttgg aactacagga ggagtaccaa caccagggaa
    24001 ttttgcaaca gcgatagtag gtccagttcc aattgcagaa atgccaccta ttagtcctcc
    24061 tattggttca acaaacttag atggtacaac acctaacaca ctattaataa cagtagcagg
    24121 ttcagatata acaaatcaaa atatattaaa tgggcctgtg atttatacac ctatagagaa
    24181 tatattggat tcttgcgtat ctgtatctaa tataaacctt attacagatg cagataacgg
    24241 aacattcggt ttttttccac caggtacacc aagtaataca ggacctgaaa tagaacctta
    24301 cccaaatgtg acgccagatt ttacgtatgt tgtaccagac ccaactaagt ttacaccttt
    24361 agatggagaa tatacagtac aaaatattat gacaaatgca atgagtaatg ttataggagc
    24421 ttggtggcgt attgctgacc atactacagg aaatgaaaca ggaagaatga tggtggtaaa
    24481 tggttttaat cctggagctg tattttttaa atcaacagta caagttacac ctaacactaa
    24541 ttatttattt agcacttgga ttttaaacct ttttaaggta acaggatatc caccaccaca
    24601 gctaggtgta agaatatttg accaaaataa taatatacta tatcaagcaa cattaggagc
    24661 tcaaattcca gttaatacaa acgcaccaga atggaaagaa gtaggtactg tgattaattc
    24721 tcaaaataat aatcaactta cagtagaatt ttttagtgaa ggagaaagcg ccattggaaa
    24781 tgattatgct atagatgatg tttctttaag agaaatagct gttccaactt ttactccaat
    24841 aaaaacaagt aacacagaaa ctgctaatgt aggtgatata atcacatata cagttacatt
    24901 agataatact tgtgatagcc ctttaactaa tgtatttttt agggatttaa ttccaaatgg
    24961 tttagagttt atacctggaa ctgtaacggt tgatggagta tctgtaccag gagtagaccc
    25021 taatacaggt ttctcacttc cagatattgg aggaggaaca ggggttgaag taacttttga
    25081 tgttgtggtt gaaagtattc ctaacccaaa tcctactaat aatatagcta atatagatta
    25141 ctcctataca cctgtagaag gcggtatacc aaatgatttt tcagtagatt ctaatccagt
    25201 tcctgttgaa gtaatatcag cagatattga agttacaaaa ttatctgaac ctactatagt
    25261 gaatccagga gaggaattaa tatacactat aaaagtagta aataatggac cattcccatc
    25321 tgaaaatgtg gttttaacag atgatgtacc agcttctatt ataaatccag agtattcatt
    25381 agatggagga gtaacttttc aaccatggac tggaagttta aatataggga cattagaagt
    25441 aggagagaca agagttatta taattagggg tattgtaaat ccatcaacag taggaattat
    25501 aacaaataca gctgtagtat cttcaactac agcagaccca aaccttaata ataatacatc
    25561 tacaatagag acagaagtga atttattagc agatatttta gtaatgaaaa cagcagaacc
    25621 taattcagct gttccaggta ctttattgag atatactatt caagtagaaa acttaggacc
    25681 agcaaatgct gaaaatgtaa tattaaatga tgatattcca gcttctatta taaatccaga
    25741 atattcattg gatggaggag caagttttca accatggaat ggaagtctta atataggaac
    25801 tttaaactct ggaatttcat taacagtttt aattcaagga acagttagtt taaattcttc
    25861 agaatatata gtaaatacag caacagtttc ttcaactaca cctgacccag atttaagcaa
    25921 caatatatct accattatta caccagttaa cccacaagca ggtatttcta ttataaaagt
    25981 agctgacgag gatgtagctg ttccaggaga agaatttgta tatacaattg aaatttttaa
    26041 tgaaggacca tctaatgcta cgaatgtagt tttaacagat gatataccag atgttatttt
    26101 aaatccagaa tattcattgg atggaggagc aactttccaa ccatggaatg gaagtcttaa
    26161 tataggtaca gttgcaccag ggcaattaat aagaattatc ataaagggat tagtaagttc
    26221 aactgctaca ggagatatta ctaatacagc agaagtaagt gcagatgtac cagaaccagt
    26281 tacggattca tcaacagtga caactcctat agttccatca gcagatatag aagtaataaa
    26341 aactagcaat atggatacag cagttccaga agaaactttc agttatacta taacagttac
    26401 aaatttagga ccatctgctg cacaaagtat cgttttgaca gatgatatac cagatgttat
    26461 tttaaatcca gagtattcat tggatggagg agtaactttc caaccatgga atggaaatct
    26521 tagtataggc actttggatg ctggagaaat aagaagtatt ataataagag gaacagtgag
    26581 ccagacagca gtaggtacaa ttataaatac agcaacaata agttcaccta cacctgaccc
    26641 aaatccagat aataatactt caacagatga aacagatata agtccattag cagatatttc
    26701 tgtgataaaa ggcaacgaac cagttgctat accaggagga agatttattt atggaattga
    26761 aattgcaaat gcaggaccat cttttgcaga gaacgtaact ttaacagata atataccagc
    26821 ttctatttta aatccagagt actcaataga taatggagtg actttccaac catggaatgg
    26881 aagccttaat ataggtactt tagatgctgg agagataaga aatatcataa taaggggaac
    26941 agtaagtcaa acagcaatag gtacaattat aaatacagca acagtaagtt caactacacc
    27001 tgacccaaat ctaaataaca atacttcaac atcagaagca gaggtaagtt catcagcaga
    27061 tatttctgta gtaaaacgaa gcaatcagac tgttgttgta ccaggagatg tactagacta
    27121 tacaattgag gtgagaaatg caggaccgtc tactgctcag aacgtaactt taacagataa
    27181 tataccagct tctattttaa gtccagaata ttcaatagat aatggagtga cttttcaacc
    27241 atggaatgga agtcttagta taggcacttt agatgctgga gagataagaa atatcataat
    27301 aaggggaata gtaagtcaaa cagcaatagg tacaattata aatacagcaa cagtaagttc
    27361 aactacacct gacccaaatc cagataataa tacttcaaca tcagaaatag atataagttc
    27421 atcagcagat atttctgtaa taaaattagc aaataaaaca gaagcatgtg taggagagca
    27481 aatagatttt gtaatagtag tatcaaatgc aggaccagaa aatgctcaaa atgttacttt
    27541 aatagacaat gtttcagata agcttaagaa agcagtattt tcacttgata gaggtgtaag
    27601 tttccaacca tggactggaa gtcttaatat aggtacacta ccagctggaa ctttaagagt
    27661 gattatatta agaggaatta taaaatcaac atgtcttgat agattaacaa atattgcaga
    27721 agttacttca acaacaccag attcaaacct taacaataat atatcaagag tgcaagtaga
    27781 aataaaacaa ttttgttgta atgattgtgg ttgtaaagat tgttgctgta attgttgttg
    27841 caatgattgt ggttgtaaaa attgttgctg taattgttgt aaaaatgact tttggtgttg
    27901 attttataaa ataattttgt ataccttaaa ttaaactgaa ataaaaaata aattcacata
    27961 tgagtaaaat attttataaa tattaataaa ttttctatct ttgatatgga ccacattcgt
    28021 aatactagtt attaaatgaa gtggtccttt ttaattcatt aaaattattt attctaatta
    28081 aattttaaat gtattaaata attttaattt tttataaaaa atattcatat gttatttata
    28141 ttaaagttta gatatctaaa aatactttta gaatttatta tattatgtta attttttata
    28201 tcttataagg attgtatttt tctaactata aaaatagtat tatacttata tttaaaaata
    28261 aaagaatttt attcctattg tgtaaagtga gaatactatt ttcttatatt ggtataataa
    28321 tagtaaatct ataatataga aaagaggtat ttctagtatg catgaaaata aaaaaaatct
    28381 attagacgga agcttagctc aatataatga tacagcagtt ccaaaaatac cagtatttgc
    28441 tggtaacgat ataacttcag aagtttatta ttttaaacct aatcaagttc ttaatgctca
    28501 tagacaccct aatggtgaac aaatatttgt gttcctaaaa ggagaaggta aaatgaaact
    28561 tggtgagcat gaatgtgatg taaaaaacgg agatactgta tttgtaccaa caggagagtg
    28621 gcatgaaatt actaatggaa gcaatgaaga aatggtagcc gttcaaatta caaaaattaa
    28681 tgctggagca gaatacagag gatagatata taagtacagt tagtacttta atatctattt
    28741 tattatataa actttaatct caaatataaa aagagtcttt taaaaggctc tttttatatt
    28801 tttgttaatt ttcattataa aaacaagaaa atatctagct aaaactaata tattttattt
    28861 aatatttttt atagcattgt ttgcaaactc agtatttacg atatctttat aaggtgcttc
    28921 cttatctagt tctttagctt ctttcataac agtcatcaat ttcttcaaac cttcctcttt
    28981 taatacagga ttttgagacc atgcatctat tgatttatat ctatctacaa ctgttgttaa
    29041 atcttctaaa gatatatctt caaagaaagg ttgcatagcc ttagctactt ctttgctaga
    29101 tgcttgttga atccataatt gacctttata aacagcattt gtaaatcttt gaattaaatc
    29161 tttattgttt ttcatgtatg atctcgtagt agagtatgct gtaaaaggta tttctccaga
    29221 atcttttcct atagatgtaa ctatatatcc actaccttct ttttccattg ctgttgctgt
    29281 aggttcaaat gctgttgtaa agtcaccctc tccacctgca aaagctccag ccattacacc
    29341 aaattgtaca tcagttctta cattaacatt gcctgctttt agattttctc caatagtaag
    29401 acctttttct tttagaacat attcaaaagt cattagtgga actccacctt ttctaccacc
    29461 taatatttcg gttcctttta aatcattgta agagaaatta ggcatttttt tcctagcaac
    29521 tagaaaacta ccatctcttt ttgtcaattg agcaaagttc actgcataat cgtttttgtt
    29581 ttgattatat acatatatag atgcttcagg acccattaaa cctacgtttg cttcacctga
    29641 aatcaaagct gccatagttt tatctgcacc ttgggtattt ataaggtcaa tctttatacc
    29701 ttcatcttca aagaatcctt tcgtaatagc agcatactgt ggagcataaa aaacagagtg
    29761 agtaacttct gctatagtta ctttatccag atttttagac gaagaagatt catctttttt
    29821 gtcattagag ttaaaatcac atccagttag acatattgta cttacaatga tagagcttgc
    29881 tattgcgact atttttttaa acataataaa tacctcccat aagacatacg aatagtatat
    29941 agtattaaat atttattgta gttgttacaa aaatgtatct atacttataa tatttctaca
    30001 aaaacttaat aataattttc agttttatgt ttagtttttt cagtaatgtg taatattgga
    30061 taaattatat tgattattta taaactaagt aataaaatta aaataatatc acttttttgt
    30121 ctattatata taaggaaaaa ttttttaata atataaatca tattcattta tattattaaa
    30181 aaatttgttt atagaaactt ttattatttt atataaaagt gataaaaact tatattttgt
    30241 atttaataga gtgttgctaa gtgaatatat ttaaaatgga ggaaacttta tgaaacaaaa
    30301 taaatatgat gatgatagat tttttaataa atacagtaaa atggaacgtt ctacaaatgg
    30361 attagcaggt gctggagagt ggcatgtttt aaaaaaaatg ttacctgatt tcaaaggaaa
    30421 aagagtttta gatttaggat gtggatttgg atggcattgt caatatgcag ttgagaatgg
    30481 agcaatttct gctgttggag ttgatatttc agaaaaaatg ttaaaagaag ctagaaacaa
    30541 aacgcaactt gataatataa attacatatg tatgcctatt gaagatatta attttccaaa
    30601 agatagtttt gatgtagtta ttagttcctt ggcatttcat tatattcaat catttgaaga
    30661 tatatgtaag aatataagta attgtctttc aaataaaggt aattttgtat tttctgttga
    30721 acatcctata tttactgcat atggaagtca agagtggtac tgtgataaag atggaaataa
    30781 tctacactgg ccagtagata gatattttga agaaggagta cgtaggtcaa attttctagg
    30841 agaagaggtt ataaaatatc ataaaacatt aacaacttat ttaaatgcgt taatgaaaac
    30901 aggatttgaa atattagaaa ttattgaacc tcaaccagaa gaaaaactgt tagatacaat
    30961 tcctgatatg aaagatgagc tacgtagacc tatgatgtta cttgtatctg caaaaaaaag
    31021 ataagtaaat ataaataatc attattgtag aaaaaaagtt gtagaaaata attacactaa
    31081 tggagatgat tataccagtg gtattaatta caccagtagt aaggaggcaa aagcattcgt
    31141 tgcttttgcc attttttaag ttgcaattat acttctacgt agtatatttc gtttccattt
    31201 tcttctataa gctttttcat atcttcaaat tttaaaaata cagtagcagt attatcattt
    31261 ggatgtatac ctattttatc catttttaat aaatccttat caaatacaac ttttacaaca
    31321 gcctctttat catttaatat accaaaagga gtcacagctc ctttagtaag tttcaagtat
    31381 ttttgaagtc tttcttctga tgcaaaacta agaggtttac tatcaatttg ttgacgaata
    31441 tcttttaaat ctgctttttt gtctttacct aatacaacta aaaaatgttc ttttccttta
    31501 gcatcacgaa gaaataggtt ttttacaaca aattccatat gtaatgtttt taattcttcc
    31561 atttcttcaa ttgtataaac tggtggatga tttacagcct cataaggtat gcttaactca
    31621 tctaattttt tatatacttc ctgttgttga ttgttcatga tttcctccca ttagaaattt
    31681 attttatata taaataatat tatcacagaa aactttaaaa gaaaacgttt tatataatat
    31741 agacaataga ttatattttt ataaagaagc aagaatactc aataaaactt aaagaaatta
    31801 aacgatttct aaaaatacct tgaaaataga accttatttg ccatttataa attatataaa
    31861 aagggattat ataaagtcat atatgaaaaa actatattat actatctttt ctttttggaa
    31921 taaactatac tttaaatata gatatttaat ttaaataaat tttacagtat taatagtaaa
    31981 ttatcttaga aaggaatgtg ctttatatgt ctacagacaa agttgttgga atcatagatg
    32041 aagaaacggc agaacttgca ggaattgaat atactggtaa aatttatgct tcttctggtg
    32101 ttataaaaca tataaagaaa aaacatagat gtcaactgag taaggatatt tttaatgata
    32161 taatagacac tataaaaatg gtattaaagt cacctgaata tataggaagt catcctaaaa
    32221 aacctggaaa aagtgtggag tttataaaaa aaattgatga ttatatttta gtagctacag
    32281 aattagatac aaaaaaagga tatttatatg tatcttcaat gtatgctata aaagaagcaa
    32341 aattagaaag tagagtaaac agtggaagag taaaacaata tgatggttaa cataatatta
    32401 ttaattttcc ctaaaatatt gaaaaatatt attatataag ttataatatt aatatacacg
    32461 tagatattta ttagttagat ttgaggttgg aaaaggcacc caatacgcta ctatagagta
    32521 gttaatagag atgcaggata cgccgccctg ccaaatctaa ttaaattaaa aagagaggat
    32581 taattcctct cttattgttt ttttgagata ctaatttaat ctataataga aagattgaag
    32641 gtcgtttata caaaaaaatt ttcagttata tacattaaac taattaaata agatatttat
    32701 aatctatatg tgatacatat tatatattaa taaaagaaaa atatatagaa aatccttata
    32761 aaaatttaaa ttgtaatgaa taggaagtaa ttaaaaagaa tttttattga tttttaaaaa
    32821 tttagttaga aactatatca ttatggtaaa aaatgtatta taatgtttag aaatattata
    32881 ataaggagcg attaaacatg aatctatcga agaaaataga agataaaaga aaagctaaac
    32941 agagagctga aaaagttaag aaagctaaaa ttgctacagc tggtgtggta ttaggagctg
    33001 ttactggtgc agtgagtgga gtacttttgg ctcctaaatc tggaaaagaa acaagagagg
    33061 atataaaaga tgcttcacaa caaattgctg aaaagataaa tatgaaaact gtagatgtaa
    33121 aaggcaaagt atctgagaag ctagaggata aaaaaggaaa ctttatagaa tcaaagaaaa
    33181 aaataaaaaa atatatagat aacaaaaaga gtgttgaaaa ttctagtgag gaagataaaa
    33241 taatagatat agttgaacca gttagtgtta ctgaggaata atatggacaa tacaataacg
    33301 attaacataa gtataatata tgtattatta gctatacttg cttgtattgc tttagtttat
    33361 ttaattattg tacttgttaa actacataag attttaaata atgttggaac tatgttaaat
    33421 gaaaatactc aaaatataaa tacaacttta aataatcttc ctaatgttgt agaaactttt
    33481 ggagaagtag gagaaaatat gaaagatgta acagaagtag ttactgaagt tacagcagat
    33541 tttcttgtta ctaaagacag tgtcaaatca aatatggatg ttatagttga tatattgact
    33601 ataattaaaa acatttttgt agataaaaaa taataagtta atataaaata agcctataag
    33661 atataattta aacgacctta aaatagcatt tataaggtcg ttttttatta gcttgatttg
    33721 acactatgtg tttttaataa ttggtaatat tcctctttat catttgaaca tatatatcta
    33781 tgcttgttgt ttcaattaca tccataagaa catctttaca ttcaagctca aaatcttcca
    33841 ttccttctaa atattcatca tcttcatcaa aaaagatata agaattatat agccattctt
    33901 caaatttttc ttcaagtata tcccaatacg aactccaaaa taatccacaa cctgatatat
    33961 aagatgctct actttgattt atataaactt catttagaag cttttgtaat ctactgctat
    34021 aaagaaaatc tgctcttcca ctgcttgata ttaattcatt taaatcttct attgacatta
    34081 attcaacttt accactttta tcataaggag tataattttc atcaacccat ttatgtggtt
    34141 tgttttctct gcatactgtt gctatcaact ctacaacttt tgttcttatc atttttttat
    34201 cctaacttat ttatttttta taaaataatc atgattttat aatttatcta tttcttgtaa
    34261 tgctaattta acagtttcat atctatcagc accatttatt actacatcac cttttacaag
    34321 tttattagct tctccaccta caacataaac ctttttacct aaaccttgct tataactaga
    34381 cgcttcaatt attaaagaat ctttcaattg ccaatgtaaa atctgagcag ccactttatc
    34441 agcatcacct gtataaacga ttacattttc atacacttta ttttcccctc ccccttgaga
    34501 atttgatata gatttgttta gtataccttc tgctatcaat ttagcaactt tatctttatt
    34561 attaacataa taatctgtat ctgctttact atctacaaaa catacttcta ttaatattgc
    34621 tggtgcaata gtatgattaa gccaataaag acctctaaca tcagactttg cacccctatc
    34681 tttgaatact gtagctaacc tagtattcac tctttctgca taggttttgc cattattagt
    34741 cttatatatt gtttctgtcc ctactggagt tgaagttgta gcatttgaat taaaatgaat
    34801 ctgaacagcc aaatcagttt cctgtttatt tgctatagca cattggtctg ctaaatgatt
    34861 acttgattca tcaactcttc ctgtataaac agtagctcca cctattttaa gccatttaac
    34921 aattaagtca ttcagtattc ttgtttcttt gctttcgttt atatacccaa cagctcctgt
    34981 accttttcca attaaagtgt gccctggtat tattactact ttcaaactaa catctccttt
    35041 acaattaaat ttaacttcta tttaatatat gcataaccta gaattttgtt tctttttata
    35101 tcttatactt ttattataac ccattttgta aaaatataga atattaagta aataatgtta
    35161 aaattataat tttgtatata agacattact tgattgcaat aattttatag catattcatc
    35221 tattctatat ccagttctat aatatatatg tttaattcca gcttgaatta tagccttagt
    35281 acaatttaag catggaaagt gagttacata aatagagcaa tttttaactg aaataccttc
    35341 ttttgcacaa taataaaggg cattttgttc agcgtgaatg gttctaatac aatgtccatc
    35401 tctcatttca tgaccaactt cactacaatg cttatctcca gaaatactac cattatatcc
    35461 agtagacact attctgtttt ctgaattgac aattatagct cctacataag ctctatcaca
    35521 agttcctctt tcagctactg tttcgcacag tctcataaaa tattcttgcc atgagcatct
    35581 attttcaagt tttttattca aatcatatac ctccaaaatt tatatctaat atataagatt
    35641 tataccttaa aaataatatt aaaaacaaat ttatatgata aataaaattt attaatactg
    35701 tttttagtct aaattatttc attttaaatt aaagttacaa ggaatctaag attatatata
    35761 tctttcttcg taatatgaat gttacaatat aaaaaactgt ctcaataaaa tagagacagt
    35821 tttacagtca aagtttataa tacaagttca tatttttctt taaattcttt tacagcttcg
    35881 ggccatgcct tttgttctgt aatacctttt tctttagcta ttttaattgc aatctctctt
    35941 atcattgcag cgccttctaa tattcccatt tttaatctcc cttcaaatat ctttttgtat
    36001 agaatataaa tagtgctaag atttattaca tgctgcatat acaatatcta tacaacacat
    36061 aacttgtaaa ttccttttat tttcatacgt ctttaaccga catataatta tattcaataa
    36121 gttttaaaat tatgaactca attataatta tttttatttt tttagaatct aaacactaaa
    36181 aattgtaggt aaatttgtct tatgccttta taaatatttc tacagtttta attactggac
    36241 atatctattt ttattataaa aagcgattaa aaatggagaa tatcctcata aaaactatat
    36301 ataagcaaaa cggttaaagg aaaaagaaga aatttacttg aatgttaaaa tgcgttgctt
    36361 gaagcaatgg gcagttttgc ctataatatc ggtaacaact gaaagaaagg tggttagccc
    36421 taatgttaag cgaaaacatt aaaacaatca ggaagtcaaa aggactttca caacaagaac
    36481 ttgctataaa actgaatgta gtgcgacaaa caatatctaa atgggaacaa ggactgtcgg
    36541 ttcccgattc tgatatgttg atttccatat cagaggtgct tgaaacgccc gtaagcactt
    36601 tacttggaga aactattgtt gagtcggaag ttgataactt aaaagtgatt tctgaaaaat
    36661 tagagattat aaacttgcaa cttgcacaaa gaaaaaacat gagaagaaaa atgtttcatt
    36721 ggttatttat tttattatgt gcagtcatat taatagtttt tgtggtctta gggagactaa
    36781 atagtcctta cttggattgg aattataccg accctgaaac cgctgttttt ggagtagctt
    36841 ttcatgcttt tgagtggcta tttgtcagat tagtaccgat tgtccttata ggagcaatta
    36901 ttggaatctt tttgacacgt aagaaaatat gaagtaactc tgctttttat aatacagcaa
    36961 gcgttcctta aaagcgtcat tctacatggc aatcgaggac gactatgtaa ggaagaacct
    37021 ttttgatttc caactaagcg aagttattga ggacgacagt aggcccaaaa ccgcattaag
    37081 taaagtacag gaagcaagac tgctggactt atactctcat gcgtcagatg caggaaatgc
    37141 gaggtctggt agcatgattt acaacgattt gtacaacgac tacgagtaga aatatatgga
    37201 gataagtatt atctacgaaa tcagaaaaga aatgacttga taatttactc atgttataat
    37261 tattgatgtg aaattaataa atcgaaattc cttttttgga tttaacaata ctgagtaagg
    37321 aaaaagtgaa ttacttttgc aaggaggtgt tatttggatg gtgctagcag gtattttgat
    37381 tgtagtacaa ggctttttga ctggtccttt agcaaaaaaa attggtgaga agcgactaat
    37441 actgataggt atgttttgca aagccttagt agcgtttgcc atggtattga caactgggtt
    37501 tgttagtgtg ttggtggttt ttggcttatt tgcggtatct tctgctatta cagtacccac
    37561 attaaacgca accctttcaa aaactgacaa tcagcataaa ggaacactga tgggatttgc
    37621 cagtaccgcc ggaaatctta gcaaagttat tgctccttta ttaactgggt atctgtatga
    37681 aagcaatatt gaattaccat atataaccac gggagggata gccttaatcg gagtggttat
    37741 ctgctatatc tggataaaaa atcaaaagaa caaatgatgg aagaggacgt ttatatggag
    37801 gttatacaca gtaactaatc tggtatagaa attcaattga ggcttttctg ctttattaaa
    37861 gtcttgctac tacttaaccc tataatatcc ttaattcatt atgacaaatt ccaattcaac
    37921 agttttgata cacataagga ggtaacaata ctatggaaaa ttatcaatga agtgctaatt
    37981 ctttatcagt gaagttatcc ataagttttt ctacctgtaa tcgtctggtg ctttttgcca
    38041 gatcattggt aggtaagaaa aattcatcaa cagacacatg aagtaatgat acaaggtcac
    38101 ttgtatgctt ggatgttgcc ctttattttc aatattagtt aagtaacgtg ggtcaatatt
    38161 tgtaattcga ttttagggaa atatttaaag aaatattttc gttttatttc tttaaatctt
    38221 caagaatatt gatagttttt tgaaagtagg tgtgtattat gaagaatgag aaaaaaatta
    38281 cagtcgcatt gctcattgtt tatttattga ttttatcatg gattatttta tttaagctac
    38341 aattttcatt ttctgcgtta gaccacataa gacaaataaa cttaattcct tttggtggtt
    38401 cagttattgc aaatggaaaa attgacttcg atgaaattat aaacaatgcc attgttttta
    38461 tccctgtagg tgcatatttc agtttgcttt ttaaaaataa atctgttcta aaagcaatag
    38521 gttctgtttt aggaattagc tttgtatatg agataattca atttatattt gctatcggag
    38581 caagtgatat tacagactta attagcaaca cattaggggg tataattgga attgcattag
    38641 tatatgtatt atctattgtt ctaaaggata aaacacataa gatattaaat cgaatagcaa
    38701 tagtatgtac tgtattagta gttgccttct tatttatgct tcttgctgta aataatatat
    38761 tttaatgcca tgttaattac atgttgtttt ggaaaagact ttaatctgtc aaagtttgct
    38821 tttgaaattg aacatgaaat tacaccaatg gaacaaatga aagctataaa tttttcattg
    38881 gagaaagatg actgtacaag taaagtatta atatacaatc cagacaaatg gaaatatgta
    38941 gaatactatt tctataaaga tagacctatt aaaaaaacta ttggaaaaat ttattcaatt
    39001 ttgcatttgt cacaataaaa tatgttttga aatattgaat acttaaatat gcaaaaaaac
    39061 aaatgtaact ggctatgggg ctatatctac taaaaagcta tgtgataggt tgggattaaa
    39121 tttaaacatc acttctagaa ggcatgaata cacaaggctg acaaactata cagttatgat
    39181 taaacgatac caacgggatt gaaaatttcg tgaagaactt tgagaagtcc tattacacat
    39241 gagcaacagc aacgaagcta ttgaagcaag gacgcaggca atctagcggt tatctgacaa
    39301 aggagttgta ggacttgaat gtagatacta tcagaacgga tataccgacc agctctgcgg
    39361 ttacagatgt gattgtgtag aatatcgagc agtcgggaac ggacacttta tctgctacct
    39421 acgaagtaga tcagcagata aaagagagag aacagacaac agcggtcaag gcaacctata
    39481 ccgtaaaagt ccatgtggac gctgacgggg atatggtaat cgttcagaac cttactcttg
    39541 caccagcaat cgaaaaatca gactatgagc caaagatatc agaaacagac gcaagcgtgg
    39601 acgctgatac cgttaatgac gctaccgcat ttctggaaac attctttgag gtgtacccga
    39661 cagccacaga aaaagaactt gcctattatg tatcggaaaa tgtgattgaa cctatcggca
    39721 gggactacct ttattctgaa ttggtaaacc cagtctttac aaaggacggg gacaatgtga
    39781 aagtcaaggt agctgtgaaa ttccttgata atcagacaaa ggcaacgcag gtgtcgcagt
    39841 atgatcttgt actccaaaag gatagcaact ggaagatttt aggataacat ggaaatgggc
    39901 ttgtatcata attatagtgt gcaagccctt ttcatattga agtatcaata atcaataatt
    39961 ataattaggt acatgaatgg agggataaaa tgttcaaaat tggtgagttt tcaaaattga
    40021 cacaagtttc tactcgtatg ttgcgttatt atgatgaaac gggtttatta aaacctgcta
    40081 aaattgattc attaactgga tatcgtatgt attcagcaga acaaatctca actttaaata
    40141 gaattatata tttacgtgat agtggcttca atgtcgctga aattgcatta gccctcaatt
    40201 tcagtaataa tgccattata gaacagcttg atagaaagtc tattgaaatt atggataata
    40261 tacaaaaaga acaagaaaaa ctaaagaaaa ttgagattgc taaaaaagaa gtgttacatg
    40321 gcaaaagtga attgtatttt aacataacca ttaaagagat accgagttat tgcgttttat
    40381 ctttaagaaa agaaatacca aattattatt atgagggcga actctggaaa gaactctctg
    40441 cttttgctaa agaaaataaa ataaatattt ctgatgaaac attctcaata tatcacaatg
    40501 aagaatataa agaaaaagat gttgatgtag aattatgtgc cattgtaaat aaaataggaa
    40561 aagctacagg agattttaag tttcgtttta ccgaaccagt ttctatgatg gcttgtacta
    40621 tggtatatgg agatttttct aatatttctt atgcttatcg ttcatttgca aaatggcttc
    40681 aagaaaacag tcaatataag atgaaaggtt caagccgtca aatagttcat cgtggaccgt
    40741 ggaacgagaa aaatccagag aactatctaa cagaaatcca aattccttta gaaaatctct
    40801 tgtaaaaaat gataatctgc cttgacttta acatggtgtt aaggtttatc gtttatttat
    40861 caagaagaaa acggaggaaa atataatgac aacttataaa gtaaattcaa taggtactat
    40921 ctgcaacaat gaaaaaggtg ctttcattca actagaagca ccatatattc tagcattaag
    40981 ggcattagac ggattcagtc atataaatgt tttatggtgg ttcagtgatt ttgataatac
    41041 gaattttaga agtgtattgg aaacagaaca gccttataaa aatgctccag agaaaatggg
    41101 gatttttgca acaaggtcgc cagtacgccc aaatccgatt gctttatcag cagtagaaat
    41161 tatcgatatt gattatatga gtgggctgat acaaattgct tatattgacg ctaatgacaa
    41221 aacgcctatc ttggatatta aaccatacac gccgagtttg gatagagtgg aaaatccgca
    41281 agttccagat tggtgtagtc attggcctca cagcttagaa gaatctgctt cttttgcatg
    41341 ggaaagcgaa ttcaattttt aaggagtgat gaaccatgag tttgcaggac tacatttttg
    41401 aaaaaccagt aattgaaaca gaacatctta ttttaagaac aatgaataaa aatgacatag
    41461 atgatttgaa agaatggatt agtgatattt ctttatacga gtattggggg aaacgtccct
    41521 caaaaagcga aaaaaatcca gaattactct ttgataagtc aaaaaaatct actaaaagtt
    41581 ttcattgggg tattgtccat aaacaagata gcaaagtgat tggtgaaata tggatatatc
    41641 ttattgaaaa taatagaatg gcaaaagtgg ctttcagact ttctaagcat tatcaaggta
    41701 atggactaat gagtgaagtg ttgaaaaacg taattgaatt ttgtttttca aaaacagaat
    41761 tacaaaaaat atggacagat gtgcatattt taaatcatgc ttcttacaag acattggaga
    41821 aagtcggttt tcaaagggaa ggacatattc gaggggggaa aatggtaaat acctattgcg
    41881 actactacct atatggaatt ttaaaatctg attatatcac taggtggtgc tatggctaat
    41941 attgaagcga cgattggcga agcaatgaac aatacagttc caaaggtcta tgatacgaaa
    42001 agcattaaaa gatatgtgat gaatttatta gatatggctc attaaaaagt accaaagaaa
    42061 taaaagttac catatagaca aaattggttt tttatatctt ttgatttctt ataagataat
    42121 ggcattgtgc gacaagctat gcaaaaaatt ttcatgtata ctttgattat aatttataca
    42181 aggaggtact gatatgtacg catatgaaaa tattgaaatg tcattaaact atattgaaca
    42241 acatttaagt gagaaaatcg aaacagagaa actggcggaa attgcctgtc tttctacatt
    42301 ttattaccaa cgcttgttta aaaggttagt taagaaatca gttcaagagt atatcaaact
    42361 tcgccgttta gcaatggtaa tagcagaatt gaataattca gaggaaagaa tattagacat
    42421 agctttaaaa tatggatttt cagaccatgc taacttcaca agagcattta aagaagttta
    42481 ccatattact cccgatgaat acagaaagaa tgttcctatg ttaaatacat ttgacaagcc
    42541 agaactttct tcacgttata tcatgattga tgaaaatgtc ccattgattg taggaaatat
    42601 tgttttggaa attcaaagaa aaacattaag aacaaaggaa acatattttg gttttgaaaa
    42661 aacagtaaat atttctgaac aaattcctgc tggagaaagt acaggaattg atgttccagg
    42721 tcagctatgg cgcgaattcc atgcaaagaa actgcaaacc gaaaatgcca tttttaacaa
    42781 tgatattgaa cttggtgtat ctcacttagc aagtccagat aaaggaacat tcctttactt
    42841 tgcaggaggt atggtttcat caacagatgt atgtcctaaa aatatggtac aacatacatt
    42901 accagcaggt gagtatattg tatgcaaaat tgaggcagaa tcttttgaag aacttgttac
    42961 tactgcttta aatcaagcaa ataagtatct gtttgaaact tggcttccaa atcataattt
    43021 ggttacaaag ccattcatgg cagaaaaata ttacaaagga aatgcagaga ttaattatat
    43081 ggaaatatgg ataattcctg tgtaaacagt aaatgctaaa taggaattat ctgacgtaat
    43141 aaaaaggaaa tagaaagctt ataaaggagg gcatagtccg ttgtgataaa cataaaagat
    43201 ataaattatg tacctaatat tagtgaaata agcgtttata ttgaaaactc tgcatttgat
    43261 gagttgtatc agcatatgaa caatgaatat aaagcagttt gcaaaatcga atacagtaaa
    43321 gatgtctggg cacgaggttg gaacgtaaag tttaaaaaat ctgggaaatc attgtgtgtt
    43381 gtctatccga agaagaacta ctttactgta ttggtggttg taggtaataa agagaaagaa
    43441 gatgttgaaa acttgttacc taggctttct gaatatgtac aggaaattta tcgtaacact
    43501 agagagggaa atggacaaag gtggcttatg atagacttaa aatctaaaaa taatgtatat
    43561 caagatgtat taaggcttat tgaaattcgt tatgccataa aatgtgtaaa accgtaataa
    43621 aaatattttt cacatacgta atctcaaggt attatcgttg agacaagtaa cctatataat
    43681 tatgggaaat gagattttta gatacttaag aaagtacttt agggggcttg cgttatggaa
    43741 agatttaagt acaattccac acaatcaaat acaatctaat aaaactttac taaaaattga
    43801 atgcaataca gctttaaagg ctcgtacaaa ctatatgttt tgtgcgggct tttttcattt
    43861 aataggaatt tggattcgtc agagagtata ttataaaaat aaaacgataa gggtacctta
    43921 aaaataaggt acctcaggct gtagacaaag tcccggactc tcgtctgggc ttttcttata
    43981 tttgagttat ccacaattca actttttaag agttatctta ttaagaaaaa agtgtatgtt
    44041 ttccacccta tagttttact tctgtgatat ttgcagatgc cactcaagta gaaagtggtg
    44101 gtacggcaga agatgtcatg cagagttcag aaagtctggg actaccgcct aattccttag
    44161 acacggaaag ctcaatcaag caggggtgta agtattttgc gtccctgctt tcttcctgca
    44221 aaaatcaagg tatcgacgat ttgaatgtag cgatacaatc ttacaactat ggcgggggtt
    44281 atgtgggcta tgtggcagga aaagggaaaa agcacacttt taatcttgca gagagcttcg
    44341 cccgtgagaa atcgggtgga aagaaagtaa cctacgccaa cccgatagcc gttgcaaaga
    44401 acgggggctg gcggtatggc tatggaaata tgttttatgt ggaattagtc aatcagtatt
    44461 taactgttcc gcaggtgtcg ggggaactgg cacaaaaggt aatgaatgaa gcgttgaagt
    44521 atcaagggtg gaaatatgtg tttgggggaa gcaatcccaa cacttccttt gattgtagcg
    44581 gacttgtgca atggtgctat ggaaaagctg gtatctactt accgagaacg gcacaaacac
    44641 agtatgacgc aacccagcat atccctttat cgcaggcaaa agctggggag ttgttctttt
    44701 tccattcaac ctataacgct ggttcgtatg taac
//
LOCUS       DAGQVA010000026        43093 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.026, whole genome shotgun sequence.
ACCESSION   DAGQVA010000026 DAGQVA010000000
VERSION     DAGQVA010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43093
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.026"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..606
                     /locus_tag="MIV85_001591"
     CDS             <1..606
                     /locus_tag="MIV85_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2960932.1"
                     /translation="ISGYLTKKLQDLNVDTIRTDILTSPTVTDVIVWNIEQSGTDTFS
                     ATYEVDQQIKEGEQTTTVKATYTVKVHVDADRDMVIIQNPTLAPAIEKSDYEPKTPEA
                     DASVDADTVNDATAFLETFFKLYPTATAKELAYYVFGNVLEPIGRDYLYSELVNPVLT
                     KDGDNMKVKVAVKFLDNQTKATQVLQYELILHKDSNWKIIM"
     gene            819..1676
                     /locus_tag="MIV85_001592"
     CDS             819..1676
                     /locus_tag="MIV85_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2960933.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPTWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVTSLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            1754..2335
                     /locus_tag="MIV85_001593"
     CDS             1754..2335
                     /locus_tag="MIV85_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2960934.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            2439..3284
                     /locus_tag="MIV85_001594"
     CDS             2439..3284
                     /locus_tag="MIV85_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2960935.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            3281..3964
                     /locus_tag="MIV85_001595"
     CDS             3281..3964
                     /locus_tag="MIV85_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960936.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIICFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVEHM
                     WKSLGGVKL"
     gene            3961..4659
                     /locus_tag="MIV85_001596"
     CDS             3961..4659
                     /locus_tag="MIV85_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960937.1"
                     /translation="MKKILSSTIQIFKQIKSDPMMFAACFSPFIMGTLIKFGIPFLER
                     ITKFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            4671..5582
                     /locus_tag="MIV85_001597"
     CDS             4671..5582
                     /locus_tag="MIV85_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBY2960938.1"
                     /translation="MEKGRLLQNKNMNKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVVSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVPSGIALTAAVLSIVIKEWMYWFTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALDIFKESINKMVDHS
                     CDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            5634..5774
                     /locus_tag="MIV85_001598"
     CDS             5634..5774
                     /locus_tag="MIV85_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960939.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            6065..6691
                     /locus_tag="MIV85_001599"
     CDS             6065..6691
                     /locus_tag="MIV85_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2960940.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNMLYQKCLVNGPISYIEDIFNEMIEKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKTQLTTHVKQFVKKYIINEKVK"
     gene            6813..7529
                     /locus_tag="MIV85_001600"
     CDS             6813..7529
                     /locus_tag="MIV85_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBY2960941.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            7679..8275
                     /locus_tag="MIV85_001601"
     CDS             7679..8275
                     /locus_tag="MIV85_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBY2960942.1"
                     /translation="MKILWIIIIMADNLLPLLLARFYPNYKHKEMALSVLGSRQSPVK
                     WIYNVWCIISGVVFCIAPYALYQENDSGWAIAIWMLLAIYGIGCEIISGVCPLNENRQ
                     DEDIITKIHGGTSAIGFMALLVVPLLFAILQFQTTKVVLGAISLVCFTIAFIFFCFFI
                     MGEKEKFANTVLRYGGLWQRLVLISCYIPLFVWSVSNQ"
     gene            8362..8553
                     /locus_tag="MIV85_001602"
     CDS             8362..8553
                     /locus_tag="MIV85_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBY2960943.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            8577..8807
                     /locus_tag="MIV85_001603"
     CDS             8577..8807
                     /locus_tag="MIV85_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960944.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            9074..9493
                     /locus_tag="MIV85_001604"
     CDS             9074..9493
                     /locus_tag="MIV85_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2960945.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            9496..9750
                     /locus_tag="MIV85_001605"
     CDS             9496..9750
                     /locus_tag="MIV85_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2960946.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            10125..10328
                     /locus_tag="MIV85_001606"
     CDS             10125..10328
                     /locus_tag="MIV85_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBY2960947.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRKLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            10406..11596
                     /locus_tag="MIV85_001607"
     CDS             10406..11596
                     /locus_tag="MIV85_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBY2960948.1"
                     /translation="MSKMKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPTGKRDDKSLREKEKQIKKDLDDGIDTIGGKMTVCQLYAKKNNQKKNIKRN
                     TEIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFHFKLSDVLEDDTEPKVILTPEQEEKLLSFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHE
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(11853..12653)
                     /locus_tag="MIV85_001608"
     CDS             complement(11853..12653)
                     /locus_tag="MIV85_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2960949.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(12848..14446)
                     /locus_tag="MIV85_001609"
     CDS             complement(12848..14446)
                     /locus_tag="MIV85_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBY2960950.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            14774..14950
                     /locus_tag="MIV85_001610"
     CDS             14774..14950
                     /locus_tag="MIV85_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960951.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            15124..16254
                     /locus_tag="MIV85_001611"
     CDS             15124..16254
                     /locus_tag="MIV85_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBY2960952.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            16495..16845
                     /locus_tag="MIV85_001612"
     CDS             16495..16845
                     /locus_tag="MIV85_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBY2960953.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            16853..17302
                     /locus_tag="MIV85_001613"
     CDS             16853..17302
                     /locus_tag="MIV85_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBY2960954.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            17404..17979
                     /locus_tag="MIV85_001614"
     CDS             17404..17979
                     /locus_tag="MIV85_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBY2960955.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            17972..19381
                     /locus_tag="MIV85_001615"
     CDS             17972..19381
                     /locus_tag="MIV85_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBY2960956.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            19565..20998
                     /gene="eutA"
                     /locus_tag="MIV85_001616"
     CDS             19565..20998
                     /gene="eutA"
                     /locus_tag="MIV85_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBY2960957.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            21016..22380
                     /locus_tag="MIV85_001617"
     CDS             21016..22380
                     /locus_tag="MIV85_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBY2960958.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            22393..23274
                     /gene="eutC"
                     /locus_tag="MIV85_001618"
     CDS             22393..23274
                     /gene="eutC"
                     /locus_tag="MIV85_001618"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBY2960959.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            23294..23947
                     /gene="eutL"
                     /locus_tag="MIV85_001619"
     CDS             23294..23947
                     /gene="eutL"
                     /locus_tag="MIV85_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBY2960960.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            23958..24659
                     /locus_tag="MIV85_001620"
     CDS             23958..24659
                     /locus_tag="MIV85_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBY2960961.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            24662..26131
                     /locus_tag="MIV85_001621"
     CDS             24662..26131
                     /locus_tag="MIV85_001621"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBY2960962.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            26227..26514
                     /gene="eutM"
                     /locus_tag="MIV85_001622"
     CDS             26227..26514
                     /gene="eutM"
                     /locus_tag="MIV85_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBY2960963.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            26641..27402
                     /locus_tag="MIV85_001623"
     CDS             26641..27402
                     /locus_tag="MIV85_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBY2960964.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYRYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            27415..28044
                     /locus_tag="MIV85_001624"
     CDS             27415..28044
                     /locus_tag="MIV85_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBY2960965.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            28086..28811
                     /locus_tag="MIV85_001625"
     CDS             28086..28811
                     /locus_tag="MIV85_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBY2960966.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            28824..29096
                     /locus_tag="MIV85_001626"
     CDS             28824..29096
                     /locus_tag="MIV85_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBY2960967.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            29089..29640
                     /locus_tag="MIV85_001627"
     CDS             29089..29640
                     /locus_tag="MIV85_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBY2960968.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGENSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQNLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            29652..30743
                     /gene="eutH"
                     /locus_tag="MIV85_001628"
     CDS             29652..30743
                     /gene="eutH"
                     /locus_tag="MIV85_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBY2960969.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            30745..31218
                     /locus_tag="MIV85_001629"
     CDS             30745..31218
                     /locus_tag="MIV85_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBY2960970.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            31731..32252
                     /locus_tag="MIV85_001630"
     CDS             31731..32252
                     /locus_tag="MIV85_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2960971.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            32631..33806
                     /locus_tag="MIV85_001631"
     CDS             32631..33806
                     /locus_tag="MIV85_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2960972.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDILKLGCEFMAKYAVEFLNKNNN"
     gene            33840..35378
                     /locus_tag="MIV85_001632"
     CDS             33840..35378
                     /locus_tag="MIV85_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBY2960973.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            35410..36612
                     /locus_tag="MIV85_001633"
     CDS             35410..36612
                     /locus_tag="MIV85_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2960974.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(36779..37378)
                     /locus_tag="MIV85_001634"
     CDS             complement(36779..37378)
                     /locus_tag="MIV85_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2960975.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            37548..38906
                     /locus_tag="MIV85_001635"
     CDS             37548..38906
                     /locus_tag="MIV85_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960976.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            38899..39531
                     /locus_tag="MIV85_001636"
     CDS             38899..39531
                     /locus_tag="MIV85_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBY2960977.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            39860..41017
                     /locus_tag="MIV85_001637"
     CDS             39860..41017
                     /locus_tag="MIV85_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2960978.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTLDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFILIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(41164..41799)
                     /gene="lexA"
                     /locus_tag="MIV85_001638"
     CDS             complement(41164..41799)
                     /gene="lexA"
                     /locus_tag="MIV85_001638"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBY2960979.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(41903..43030)
                     /locus_tag="MIV85_001639"
     CDS             complement(41903..43030)
                     /locus_tag="MIV85_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBY2960980.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
BASE COUNT        16246 a         5669 c         7712 g        13466 t
ORIGIN      
        1 atcagcggtt atctaacaaa gaaattgcag gacttgaatg ttgatactat tagaaccgat
       61 atactgacta gccccacagt tacagatgta attgtgtgga atatcgaaca gtcgggaacg
      121 gacacttttt ctgctaccta cgaagtagat cagcagataa aagagggaga acagacaaca
      181 acagtcaagg caacctatac ggtaaaagtc catgtagacg ctgacaggga tatggtaatt
      241 attcagaacc ctacccttgc accagcaatc gaaaaatcgg actatgagcc aaagacacca
      301 gaagcagacg caagtgtaga cgctgatacc gtgaatgacg ctaccgcatt tctggaaaca
      361 ttctttaagc tgtacccgac agccacagca aaagagcttg cctattatgt atttggaaat
      421 gtgcttgaac ctatcggcag ggactacctt tattcagaat tggtaaaccc agtacttaca
      481 aaggacgggg ataatatgaa agtcaaggta gctgtaaaat tccttgataa tcagacaaag
      541 gcgacgcagg tattgcagta tgagcttatt ctacataagg atagtaactg gaaaattatt
      601 atgtaagaca ttttgttggc aggatctatt ttcggatata gtctgccttt tctgtagcaa
      661 atgtactgca ctgacaagct atttcattgt attttaagca attaaacctt tcttgacaat
      721 tttatcttaa atcatatatt tatggatatt gactttctgc ttgcaataag ctataatatg
      781 actataaaat caaatcagtc atataggagg tatgtggtat gtataaagaa gttggtattt
      841 cttcaaataa tgttccgata acactttcta tctggtatac agaaagaagt agtcctacca
      901 ttgttttttt gccgggtact atgtcacacc ctctcatgta tgagaatttt ctatgtggtt
      961 tgagtgaaag aggatttaat ataataggca ttcactatct ttcacacgga aaaagcccta
     1021 aaatcaaaaa aaattataca atggaagatt tgctgcataa tgtatatgac gcaacaactt
     1081 acggaataga aaatttcggt gaaaacatag ctgtcatggg ttccagtcaa ggcgggattt
     1141 tagctgcaat ggcggcaggt agggacacaa ggttaaaagc cgtttttcca cataatatca
     1201 tgctgaccac attaaaagaa actatgagct taacaaaata tcccacatgg tcgcaccgtt
     1261 ttatggggct gatacagtgg ggctttcgtg taggtggaaa attgctgcct aactacaagg
     1321 ttccaggaga cgcttattta gactatgaca gagtatttta tagtgaacag gcaaaacaag
     1381 attgcttaaa tgaccctatg cttttaccct attatccttt aagatttgtc accagcttat
     1441 ttaatgctga cttatcgtgc ctggagaatg gggctataca atgtcctgtt attttaatta
     1501 ctgccaaagg cgacccgctt tttagctttg attataccaa caaagtattt gatttaattc
     1561 atgtaccgca aaaggaatta cttgctttag agcttaatcg tcacatgatt tttaatgagg
     1621 acacggacac tacaataaac gcattggaag ctaccttgca taaatatctt ggatagcata
     1681 ttgattatat aatcagtaaa tgttatactt ttcatgacga tataaatatt ttagtcataa
     1741 ggaggttatg agtttgccac gatttacgga acaagaaaaa gaaatcataa acagtaaact
     1801 tttgatagag ggagaaaagc tgtttgcatt acacggctta aaaaaagtaa cagttgatga
     1861 tttagtagct gctgtaaaca tatcaaaagg ttctttctat gctttttatc ccagtaaaga
     1921 acatctatat gttgaaatca attttcgctt acaaaaagag ttatttacaa gtatagaaac
     1981 aaccattaaa aagaaaaagt ataagaacca tagagattta gcaaaggacg ttatcatgct
     2041 aagtttaacg ggggtgatta cttcgcctat tctttcacag attgatttat ctttaatgga
     2101 ctatctgcaa agaaaaatat cgtcagatat ttttgaaaat catatgtaca gtgatattcg
     2161 tatattggag atattggaag atttaggggt tgtatttttg gttccgcata cggttattat
     2221 aaaatccctg tattctgtct tatcctgttt ggaacaattc aaagaggacg aagaactgaa
     2281 tatgatacaa aatcttttag tgaatggtat tattcagcaa gtagtagcag agtaacaatt
     2341 ttgtttggtt atttgacagg caggtagcca aacaaatttt ttacagttta tatgactata
     2401 tatctataaa cgtcataaag ttaaaggagg aatgaataat gattgatgta aaaaaactgt
     2461 attttagcta tactgacaaa ccgtttgtgg agaatgtaag tttccatgtt gggagaggag
     2521 aaatttttgg ttttttagga ccctctggtg ctggaaaatc aactattcaa aaagttttaa
     2581 ctgggcttaa tacaagatat aaaggcagtg taaaagttgc aggtacagaa ataagggagc
     2641 atacaaatca gttttatgaa aatattgggg tagactttga attttcaacc tgctacgaga
     2701 aattcacagc acgacaaaat ctcgcctatt ttgcttctct atatgaaaag caacctcggt
     2761 ctattgatga attattgcat atggtaggct tggaaaatga cggggacaaa aaagttgctg
     2821 acttttccaa aggtatgcgt tctcgcttga atttcattaa agcgttagtc catgaccctg
     2881 atatattatt ccttgatgaa cctacaagcg gtcttgaccc tacaaatagt cgtttaatga
     2941 aagatattat tcttgcggaa aagaaacgcg gaaaaacgat tatcattact actcacaata
     3001 tgtttgacgc aacagagcta tgtgaccaag tagcctttat cgttgccgga aaagtcagtg
     3061 cattggatag cccgcataat ttgattatgt caaggggagc tgccaaaata caatatacct
     3121 actatgataa aggcgagaaa accggagaat gtctgcttga tagaaccaca gaagataagt
     3181 tgttaaaaag tttaatttcc gaaaaccgtt tgctttctat tcatagtagt gagcctacat
     3241 taaatgatat ttttgttgat attacaggga ggacacttca atgagattgg gacgtttaat
     3301 ttgtggtgat atacatttcc aatggaaata tggtttctat tttatctact ttatattaac
     3361 agttttatat gtgtgcggga ttgccgcttt gccggaacat tggaaaacgg atattgcttc
     3421 tattatgatc tactctgacc cggcagcaat gggattattt tttatgggag cgattgtcct
     3481 cttagaaaaa agtcaaaagg tgttaaatgc tatggtggta tcccctgtaa aaatatcgga
     3541 atatatactt tcaaaaacag ttgcgttgat tgctatttct acggtaatcg cattgatatt
     3601 aggggtagtt tccggcagca atcatttact gggtatcgca gttggtacgg ctttgacctc
     3661 agcaatcttt actatgcttg gaattattgc agctacaaaa atttcaaact tgaaccaatt
     3721 tctcattgtg attatgccga tagaaattat ttgctttgta ccacctattg ttggtctgtt
     3781 tgtgaagtta ccatatctgt tccgcttttt tccattcaca gcttgcatga accttataac
     3841 tggaaaaagt gttttactat cgtttgatat ggtacttgta attgctacgt tgattatcct
     3901 ctacatagtt gctcgacata cagttgagca tatgtggaaa agtttgggag gtgtaaagct
     3961 atgaaaaaga tattatccag caccatacag atatttaagc aaatcaaaag tgaccctatg
     4021 atgtttgcgg cttgcttctc cccttttatt atggggactt taattaagtt tggtattcca
     4081 tttcttgaaa gaataacgaa gttttcttta caagcgtatt atccgatttt tgatttatta
     4141 ctttctatca tggctcctgt attgctctgc tttgcatttg caatgattac attggaggaa
     4201 atcgacgata aagtgtcacg gtacttttcg attacccctc ttggtaagtc ggggtatctc
     4261 tttacaaggt tgggagtacc ctcaattatt tcggcggtca tcgcttttat tgtactgtta
     4321 cttttttcat tagaaaagtt gtccattgga atgacaatat gtttggcgct tctcggctca
     4381 gtacaggcaa ttattgtttc acttatgatt atcacattat caagcaataa attagagggt
     4441 atggcagtta caaaactagc tgcacttaca ttgctcggaa taccagcccc cttttttatt
     4501 gatagttact accagttcgc ggttggcttc cttccatcat tttgggtagc gaaagccatg
     4561 cagaatgaag cggttcttta tttctccata ggattggtgg tagctttagt ctggtactac
     4621 ttccttacaa aacgtctgtt tcggaagctg gcaggataag gaggcatatt atggaaaaag
     4681 gtagacttct gcaaaacaaa aatatgaata aggctattca ggtttccaaa attacactaa
     4741 tcatcaatct gagtttatcg ctacttaaat ttgctgccgg atatatagga aagtcaagtg
     4801 ccatgctgtc ggacgctgta cattcggctt ctgatgtagt aagcacaatc gttgtgatgg
     4861 ttggaattaa aatatcagaa aaacagcctg atagagaaca tccttatggg catgaacgta
     4921 tggaatgtgt ggcttccatt attctctctg ttgcattggc tataacgggt gctggaatag
     4981 gatattcagg tatcaagaaa atcttttcag gacagtacaa tacgctttct gtccctagtg
     5041 gaatcgcact tacggcagca gtcttatcta ttgttataaa agagtggatg tactggttta
     5101 caagaagtgc tgcaaagcat acaaattctg acgcacttat ggctgacgca tggcaccacc
     5161 gctctgatgc actctcgtcg gttggttcct taattggcat tttaggagcg cgtttaggct
     5221 atgctattct cgaccctatt gcaagcgttg tgatttgcgg ttgtatctta aaagctgctt
     5281 tggacatttt caaagaaagc attaacaaaa tggtagacca tagttgtgac aatgctactg
     5341 aaacaaagat tagggaagtt gtgcttcagc agcaaggggt tgatggtatt gatgaattaa
     5401 aaacccgcat gtttggagcg aaaatgtatg tagatattga aatattagct gatggtaatt
     5461 tagctcttta tgacgctcat agaattgctg agggagtcca tcaaacgatt gaaaacaact
     5521 ttccacaatg taagcattgt atggtacatg ttaatacgaa tgaacttctc tattctgcat
     5581 aggacaggga agatgattta aggctattga aagggaaagg agggaagtag gttatggaac
     5641 aatactggtg gattatcatt gttgtggttt tgattgtcgt tggcttactt aaaattgtaa
     5701 ttatgaagaa gtataaccaa aggagaaatt ctaacaatcg ttcaaaagat agcgaggacg
     5761 acaagatgta ttaaggttta ttgaaatctg ttatgttgta gaatgatgtt tttagatact
     5821 agaaagtgct ttaagggggg ctaacgttaa ggaaagcttt gagtacaatt ctttacaatc
     5881 aacagtcttt tgcatagaga aatgtatgta ggaaatatgg tgcaaggcac aaaacaccag
     5941 caattgagaa atcaacctat gaaccaaagg cacactacat tttatactac ttgacaagta
     6001 aacgaacatt tactttaatg gtttaaagaa gtaaacgttc gtttactaaa gaaggaggtt
     6061 gtaaatgtct gacacaaaag aaaatatatt aaaaattgca ctacacttat ttgcagtgaa
     6121 tggttatgag gctgtttctg ttagtatgat tgcggaagcc ttgggaatga caaaaggagc
     6181 attatataaa cattataaaa ataagcaaga tatttttgac tgtatcgtag aacgtatgta
     6241 tcaaattgat aataagcgag ctaaggatta tcaagtacca gaaagcacaa tagaggtaac
     6301 cccaaatgca tacagaaata caactattgg aagtctaata acatttactc ttgcacaata
     6361 cgatttttgg gtgactgatg aatttgcgtc taattttcgc aaaatgttaa tactagagca
     6421 atatagaaat ttaaaaatga atatgcttta tcaaaaatgt cttgtaaatg gtcctatcag
     6481 ttatatagaa gatatattta atgaaatgat tgaaaaaggt gttcttcaag agtgtgatac
     6541 aaaacagctt gctattgaat attatgcgcc attatttcta ttgataagtg tagcagacgc
     6601 agttgaaaat tgttgggatt taaaaactca attaactaca cacgttaaac aatttgtcaa
     6661 gaaatatatt ataaatgaga aagtaaaata atcctttatt ctgtcctaaa tataaaccta
     6721 actttttaat ttcagcagag aaactcaaaa tgaatattgt tataagtcac aaatattaac
     6781 tattaaaata ttacaataac ggagatgaga aaatggaata tattcgcagt aaaaaatatt
     6841 ttacacccga cttacagaca aaaattatgg ggccgaatcc tataaaatta caagaggaac
     6901 tattacaaaa tcataaaatc ccgtctggta gctatgtctg tgaccttgga agtggacaag
     6961 gtttaacttc tgtatttctt gcaaaagaat atggatttgt tgtttttgca gttgacttat
     7021 ggagtgagcc aaaagaaaat gaagaatttt tcaaaaaaat gggattatct tctgcacaaa
     7081 ttaaatctgt aaaagctgac gccaatgaac ttaaatttga gaaagagttt tttgatgctg
     7141 tagtaagtac agattcatat aattattttg gacgtgaccc tatatattta gatgaaaaat
     7201 tgcttccatt tgttaagaaa ggtgggtttg tttatatcac agttcctggc atgaagaaag
     7261 attgccatga gaaacttcca gaagagttat tgttatcatg gacaccagaa gaacttgatt
     7321 atatacatga tataacatat tggtctaaca taattagtca ttgtaaaaag gcagatttaa
     7381 tttcaatata tgaaatggaa agtaattcgg aagtttggtc ggattggata aagcaaaata
     7441 atgaatatgc aataaatgac cgtaaggcaa tagaagctgg cggtggagat tatctgaatt
     7501 ttattgctat aattctacaa aaaaaataaa ttctttagaa ccaaacacta taatttgcgt
     7561 tctaatatgt ttaccgattg acatcaataa ttttatcttt gagggtaatg atttgaaaat
     7621 agaagaatac aagaagatac gaaattgata aattagaatt tgatgggatg gtgatattat
     7681 gaaaatatta tggatcatta ttattatggc agataatctg ctgccgttac tgcttgctcg
     7741 tttctatcca aactataagc ataaagaaat ggcactatct gtccttggct ctcgtcaaag
     7801 cccggtgaaa tggatatata atgtgtggtg cattatatca ggtgtggtat tttgtatcgc
     7861 tccatatgcg ttgtatcaag agaacgatag cggatgggca atcgctatat ggatgcttct
     7921 tgctatatac ggcatcgggt gtgaaatcat ttccggagtg tgcccgttaa atgaaaatag
     7981 acaagacgaa gatataatta caaaaattca cggcggcaca tcggcaatcg gatttatggc
     8041 cttgcttgtc gttcctttgc tctttgcaat tctgcaattc caaacaacaa aagtagtgtt
     8101 aggcgcaatt tcactggtgt gctttacaat agcattcata ttcttctgct tttttattat
     8161 gggtgagaag gaaaagtttg caaatactgt tttgagatat ggcggtcttt ggcaaaggct
     8221 tgttttaata agttgttata taccgttatt tgtttggtct gtttctaatc aataaaattt
     8281 agtttatagg aataacaaat tccagtttgt aaaagtcaat aaatccaaag ataaatttgt
     8341 atttgaaagg agttttgaag aatgaaaaaa tatgagtatg tagaaattaa ctataatgcg
     8401 aaaggagttg tattcctttg tactgataaa cacaaagaaa ttattgacag ttacgcaaaa
     8461 acggggtatc actacgcagg gtttgtaccc acagaaattg acgcaaaagg ctgtatgcga
     8521 aagatagatt taatttttga aaaagaagat taacttattt tagggagttg gttctaatga
     8581 taggacttaa aagacgagat atgaattata ttatgaaagt tggtgctaaa gctcaaggtg
     8641 tttctgtatc tgaatttagg gctatgctac aagataccat agacaaaact atggaaagta
     8701 cagacccaga cgtgcaggca aattttaaac gatactttgg aaataagcgc ccaacaccag
     8761 aggaatatat ttatacgatt accaaaaaga caaaggttaa ggtttaaatg ttgtaaaggg
     8821 ggcttgccgt atgaaacgct ttatgtacaa ttcagtatat tcaagcccaa tttaacagca
     8881 tactatttac aattaaatac gctataccag tagctcgtac aaaatttata ttttgtgcgg
     8941 gcttttttaa tacccgaaaa gtttttttaa ttattttcat ttttttggaa gcaaatcaca
     9001 ccttgctgta cagatatggt gcggaaagag ggataaacac ttttcaattc atagctggaa
     9061 aggaggtgag attatgaaac cgtctgactt ccaaaaaaca attcagtgtc agtttgaatg
     9121 taagctgaaa aaagttgtca aaggtattat ctggaactac cgtaaagaat taaaacgaag
     9181 aaaaaacaag gaaatatctt ttagcgaatt accagacatt acggtagaaa gtctggcaac
     9241 atgggacgac tacgaaacaa actacacaat ttttaatgtg tgtggcatag atattaaagt
     9301 ccttgatgat gaacttgcag aagctctcaa acagctaccc gaaaaaaaac gtaacaatgt
     9361 attgatgtat tacttcttgg aaatgagtga tacagagatt gcagatatta tgaattatac
     9421 cagaggggct gtgttcaaac acagacaccg tgcactagaa actatgaaag agatactaaa
     9481 ggagaagaaa tagaaatgaa gaaaaagtac aagcacccgt cttattattt gatttcatca
     9541 gctatggatg gggatgaaac tgcgattgag aaattactgg cattctatga cccgtacata
     9601 tcaaagtgtt gtttacgtcc tttatatgat gaatacggca atgtttatat tgttgttgat
     9661 atggaattaa agggacgtat tcgagaagcc ttaatcaaaa tgattttaga ctttgagatt
     9721 gatatagata tagaaaccga agaagaataa gcaaatacca gcagggcgtg attggttaaa
     9781 ttcccttctt tcctgccctg ctcctgcttt tatacatgga agcctacggc tttcgccgat
     9841 tgttctttga caactgaata aagcagacag atacgtttgt gatacagcga gccacgggga
     9901 ctgtacgcca tgacctttcc gacaagaaag cgagcgaccc acgcagttga tccgagagcg
     9961 acttgtggaa tggtcgtttt gccatgacct gctatcacag aataatgata cgtccgcatg
    10021 gtgcggttct gcccacaaga atgggaatag ttgagatact aacggagctt tccaaagccg
    10081 tctgtctgct tatgataaga cacacagaaa ggagttgttg caacatgaac aatactgatg
    10141 tgccgatttg ggaaaaatac acccttagta tagaagaagc gtcccgatat tttcgtatcg
    10201 gggaaaagaa gttgcgtaaa cttgccgagg aaaatctgga ctctggttgg gttatcgtta
    10261 atggaaaccg tattcagata aagcgaaaac agtttgaaaa aattattgat acactggacg
    10321 aaatctgatg tcttagagcc gtagatatgg tataatatta gtagcgtatc acggctcatt
    10381 ccatgacgga aaggagcttt acactatgtc aaaaatgaaa agacaagaca gtaaaggacg
    10441 caatttgcgt cttggagaga gccagagaaa agacggaaga tacgtttata aatataccga
    10501 tatattcggg aagccacagt ttgtatatgc ttggaaactt gtaccgacag acaaaacacc
    10561 tactggaaaa cgtgatgata aatcattgag ggaaaaagaa aagcagataa aaaaagacct
    10621 tgacgacggt atcgacacta tcggcggtaa aatgacagtc tgccagcttt atgcaaagaa
    10681 gaacaaccag aaaaagaaca tcaagagaaa cacggaaata ggacgacagt atcttatgaa
    10741 cgcactagaa aatgacccat taggtatgag ggcgattgat acagtcaaac agtccgacgc
    10801 taaagaatgg gctatcagaa tgaatgacaa aggttattcc tataagacaa tagataacta
    10861 taagcgttcc ttaaaggctt cattctatat ggcgatacaa gacgactgta tcagaaaaaa
    10921 tccttttcat ttcaagctaa gtgatgttct ggaagatgat acagagccta aagttatctt
    10981 gacaccagag caggaagaaa aacttctttc ctttatggaa acggataatg tttacagcaa
    11041 gtatcgtgat gaagttattc ttctgctgga aacgggactt cgtatctctg aattatgcgg
    11101 actgacaaca cacattgata tgcttaatcg tgtgattaac atagaccacc agctattacg
    11161 tgatacagag gtgggctact atatttccac acctaagaca aaaaacggca agcgagagct
    11221 tccattgaca gaaagagcat atcaggcact tgaacgaatt ttaaagaacc gaggaaaagc
    11281 tcaaccgctt gttgtagacg gttatagcaa tttcttgttc ttgaaccgtg agggcttgcc
    11341 aaaggtagca ggaaattatg aaagtatggt gcgtgggctg attaagaagt acaacaagac
    11401 ccatgaggac aagttgccga acatcacgcc ccactcattc agacatacct actgtacgaa
    11461 catggcaaat aagggaatga accctaacac cctgcaatac atcatgggac acgcaaacat
    11521 aaccatgaca ttagggtatt atgctcacgg tactttccag tctgcaaagg cagagttgga
    11581 aaggctggct tcttaatatc gaaaatgtat cttactactt atttactact tttggttgca
    11641 ttttcatgct ggtaaatgcc agcttatgcg aggtatcttc caaaaagaaa atgcccatac
    11701 agcccgaaaa tacgggatat atcggcattt accaacttat gaaaagataa tcagaaatta
    11761 gtaagttttt atatcaaaaa aatgattact gtaaagaaat cattttttat tataatcact
    11821 gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat tttttctata
    11881 atattaacta cagcgtacat tgcccaagca cagatagcca atacaaatac tcccatcatt
    11941 actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat tccatatctt
    12001 gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt aattttagtt
    12061 aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat ttgagattta
    12121 gtagctccaa aactttttaa catcttaatt ttttcttcat ctatattcat aaaataatta
    12181 taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac gattccttct
    12241 attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg aagagcattt
    12301 aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca aagagcaatt
    12361 gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc atatacagat
    12421 attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa attgtaaata
    12481 tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa aagttcccag
    12541 attacaataa aaccaattaa aattaatagc tggtagaata atacatttct tttttctctt
    12601 tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct catgtgtatc
    12661 tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac gtgttttgag
    12721 aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta tggtagctgg
    12781 tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta tagctaaaaa
    12841 agtgcaacta attgcttaaa gaaacagaat tatcaacttc agcacccata taaacaatat
    12901 taagatttcc taaactgcta tcccaaacga tactattaat aatagtagat aataacaatc
    12961 tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa ttactaacaa
    13021 taatatcaat attaatactg tcactactaa tattgatgtt actagattcc aaaatattaa
    13081 tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa actatataat
    13141 cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta ataagtcttt
    13201 ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata ttaaaaacat
    13261 tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct ttacaattct
    13321 taattttatc tataactaaa ctttcaacta atggaccatt aagattttta cagttgcaac
    13381 tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa tccttgtcag
    13441 tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat tttataagac
    13501 cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga tttttatcta
    13561 attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt tttgcaattg
    13621 ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt ctatctggag
    13681 tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca ttagctttta
    13741 catatgctgg atttctaagt attctagata aagaactagg gtcaaatttg ccaccacgag
    13801 gaccccttat tccattatta tagacatatt tatataactt agataaggac ctaagttcta
    13861 aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact tgaagcttat
    13921 acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg ttgaatccat
    13981 gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacata ttgtctttta
    14041 tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata aacatcatag
    14101 ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat gatatgctta
    14161 gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat atcctatcta
    14221 atctataaca aactaggtaa ctaaatttct tatctttggc atcctgcatc attttcttaa
    14281 attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc aaaaaatctt
    14341 ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct atagaatcac
    14401 cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt aaaaccccct
    14461 ataagttagg atatatattt gaaactattt atctacaacc ttttaagtaa acttattaga
    14521 atgaatttat taattaggta aatttatata attctacttt ttataatata tgactattta
    14581 ttttatttct ttactattca agttctaaat caataataaa ttttgatatt taattgtatc
    14641 aggacaaatc tctaatttca tagattatta atataaaatc ataggttagt gtgaaaaagt
    14701 tgaaatttaa atattttaaa agataatttt tttgaactaa taggtataac aaaaatttat
    14761 agggggattg catatggaaa tcaatgttat agaaattttc cctaaagata aagctaaact
    14821 taataaaata gaaatggata aagctagttg gtttgtaaat ataataagta aaaaatatcc
    14881 taaagaagct ttaaatgaag catttagtac tttagaaaaa gaattaaata taagtaaagc
    14941 taatacataa gctttgatta ttgattttat atactattgg ttttatacgc tatgacttga
    15001 cattatatta atcaaatagt atatttttaa atatagcaca atgaagtgtt aaaagagcaa
    15061 tggagctcca tagataaagt ctatggagct tttttgcgta tttaacttaa ggaggatagg
    15121 actttgaata actttgagat taaaactaga ataaaatttg gagaaggctc actaaaagct
    15181 ttgcaagaat taaaaaacaa aaatgtacta ataataacag acccttttat ggtgaaatca
    15241 aaaacaatag ataaaataac atctaattta ataaactcaa catatcaagt ttttgaagaa
    15301 atagtaccag acccaccaat agaagtagta gtagcaggaa tagaagcatt taaatctata
    15361 aatccagacg taataatagc attaggtggt ggttctgcaa tagatgcagc aaaatctata
    15421 atggactttt ctaaaaaaat attaaaaatt aacgaagtag agtttatagc aataccaaca
    15481 acaagtggaa caggttcaga agtaacatca tttgctgtaa taacagatag tcaaaaaaaa
    15541 tgtaagtatc cattagtgag tgatgattta cttccagata tggcaatact agacccagaa
    15601 cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag ggatggatgt attgacacat
    15661 gctatagaag cttacgtatc tacaaattct aatgactttt cagatgcact agctgaaaaa
    15721 gctataaagt tagtatttaa atacttaata aaagcatata aagatggaaa tgacatagaa
    15781 gctagagaaa aaatgcacaa tgcatcttgt ttagcaggta tggcatttaa ccaagcatca
    15841 cttggcataa atcattctat tgcacatgta ttaggtggaa aattccatat accacatgga
    15901 agaacaaact ctatattact tcctcatgta atagaatata attcatcaat agtaggatat
    15961 actaacacaa cttactctgc tacagctaaa aaatatgcac aaatagcaga attagtagga
    16021 cttgggagtg ctaatataag aatatctgtt agaaatttag taaatgaaat aaagaaacta
    16081 caaaaagaaa tgaatatgcc aactaaattg acacaatgca aattaagttt agaagatata
    16141 actaatgaag aaagagaaat agcaaaactt gctataaaag atacttgtac attaactaat
    16201 cctaaggtac caactgaaga tgatataata aacatattaa agaacattaa ataactacat
    16261 tttattacat gtaaatataa tattatacaa atagggaaaa tgtttttaaa aatataaatt
    16321 atatattgac aaatataaaa cataaaacta taatgaaagt atcacaaagg cgtgatactt
    16381 tagtagaaag caatggagct tcttaggaat attaatatta ttcttatgga gctcctttta
    16441 ttttaatcaa atagcttttt aataaactat attcaaagaa agcagggaat aaatttgact
    16501 gaagaatcta agcaaagagt tattcaagaa tatgttcctg gaaaacaggt tacattagca
    16561 catatcatag ctaaccctaa tgaagatata tataagaagt taggattagt acttgataaa
    16621 aaagatgcaa taggaatact tacaataaca ccaagtgaag cgtcaataat agcagcagat
    16681 gttgctacaa aggcttcaaa tgtatcttta ggttttatag atagatttag tggttcagta
    16741 gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa atgatgtttt agaagtctta
    16801 ggaaatatgt taaacttctc atctacaaaa atcacaagga cataataata caatgaagaa
    16861 tataatattt atgggaaaga caggtagtgg taaaactacc ttatgtcaaa aactagacca
    16921 gttagaatta aagtataaaa aaactcaatc agtggaactt tataataatg caatagacac
    16981 tcctggtgag tatatggaaa atagaaacct atataatgcc ttaataacaa catcagcaga
    17041 tgctaaaatt atagcaatag tgtatgatgc cacacaagaa gaaaattata tagcaccagg
    17101 ttttgccagt atgttttgca aagacgtaat aggaattata actaaaataa ataaagctac
    17161 tgaaaacgaa gtcaatatag cttatgaaag actatcacta gcaggagcaa gtcaaatctt
    17221 taaaatagac acagttgata atattggact tgaaaaatta tttaaatatc tagaaaaata
    17281 taaaaatata gatgaagttt aaggggaaat atttttttat tcaaaaatat tattaaagta
    17341 tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa gcgaggtagg
    17401 aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat ggatacaaaa
    17461 gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg atttgaagct
    17521 gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga gatgccaata
    17581 cttgatggta taaaggcagg caaaataata tgtaaagaaa atatagctgg tggagtactt
    17641 ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat aggtgcttat
    17701 ggatatttag taaaaacagc aagtgaaaaa tcacttatcc caaccataga aatgtgttta
    17761 aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa ttctaaattg
    17821 aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt taagatttct
    17881 gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac tacaatgatg
    17941 gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa aaatatcaac
    18001 tgcacaaaca tacttaaata ataacgaaat tgaaaaaatt atagaagtat caaaatcctt
    18061 agatttaatg gcttcttttt atgaagctga tgtttttata gatgtactaa gtaaatttga
    18121 tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt actgtgaaaa
    18181 tgttataggt aaaaaggctt taattgaaaa tgaaccagga gttataaagt gcttaaaaac
    18241 aggagaaaga gtaagagata ttaaagcttt aacacaggaa tataaactgg tcaaacaaaa
    18301 tattcagcca ataacactag atgacaaagt tttagcagta ctaatagttg aaaaagatat
    18361 aagtagtgaa gttaagaatg agtttaatgc tagtgaagac gaagaaaata aaaatttaca
    18421 tcagtttata aaacttattg gaaataatga ctttttagtt gataatttaa attcagccat
    18481 attaatattt gataaaaatg gaaaattaaa aattaaaaat cgtattgcaa ctgagatata
    18541 caaaaatctt gggtttggat atgatataca agatatgcat tacaatgatt tagatataga
    18601 aaccaacacc tttgaaaata tattaatgga tgaaaattat gatgagacaa atgaagtttc
    18661 aataggtaat atgtttttta aaataaagac catatacatc aaagatgatg aatttaaggt
    18721 ttgcaaaata gtacaagata taagtgattt aaagagaaaa gaagaagaat tagttttgaa
    18781 aacagtggct ataagagaag ctcatcatag agtaaaaaat aatcttcata cagtaatatc
    18841 tataataaaa aaacaaagta gattatctca aaatgatgaa gtaaagcagt gtttagataa
    18901 cataataaat agggtatttg caatactttc gactcattat ttactatcta aagaagttga
    18961 taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc aaggtggcta
    19021 tttatttagt aaggatatag atatacgtat aactggtgaa gattttaaaa ttagtggaga
    19081 aaaagcaaca gcaatacttt tggttataaa tgaaatacta caaaattgtt atgaccatgc
    19141 attttcggat agagaacatg gtactataca aatattaata aataaagata acgactatag
    19201 aaatattgct attatagatg atggaattgg atttgatagt aataatataa ataaaaatag
    19261 cttagggaca tatataatag atagttatat aacacagatg ttaaaaggaa atatagagag
    19321 aaaaagtagt gagaatggta cagaagtatt aattactata cctacacaaa ttaatattta
    19381 aataataact catctacaaa gtagtagttt taattgagca aagaggctta aggttattaa
    19441 tagattaagt taattgaatg tatttataaa aattataagt atatattcaa tttaacaggt
    19501 atttattata actttaagcc tctttgcttg tttaagacat acttaaattt taggaggtga
    19561 gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta ctactcagtt
    19621 aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcggtac ctagaataag
    19681 tatagtagac aaagaaatta tttataaaag caaagtttat ttcacccctc ttatttcaaa
    19741 taatgaaata aatggtcaac aaataaaaga tatagttgaa aatgaatata aaaaagcaaa
    19801 tatatctaaa gaagatatac atacaggagc agtaataata actggtgaaa cagctagaaa
    19861 agaaaatgca aatgatgtac ttcatacttt gagtggattt gctggggact tcgttgttgc
    19921 aacagcagga cctgatttag aaagtataat atcaggaaaa ggagctggag ctcatattta
    19981 ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa ctagtaacat
    20041 agcctcattt aaaaggggag aagtaaccga tactgggtgt ttggatatag gtggaaggct
    20101 tgtaaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa tagataaaat
    20161 cataaaagat aataatttaa atcttcaagt aggtacaatg gctactgtag aaaatacaaa
    20221 gccaatagtg gatataatgg ttgacttatt aatggaaagc ataggactaa agaaacagac
    20281 acctttgttt gattttataa taaccaataa atcaataagt atagatgaaa atattaaaaa
    20341 tgtttcattc tctggtggag tagctgatta tatttactat gatggagaaa taaaagatta
    20401 ttttgaatat ggtgacttgg gaattttact tgggcaagca ataaaaaatt gtgaatacct
    20461 taaaaaagta aatgtagtta aatctatgga aacaataaga gccacagtgg ttggagcagg
    20521 ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa agtttccact
    20581 taagaacttg ccagttttaa aattatcaat tgatgaagaa acaggtactt caaaacaaat
    20641 cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt tacagaaagt
    20701 tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag agtatgctaa
    20761 agggtttgta gatggaatgc aacaaatcat agaaaatgat ttacctttta tagtaattgt
    20821 tgaaaatgat atggcaaaag tgttaggtca agcaatatat gcattattaa attatgaaaa
    20881 agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg acattggaaa
    20941 acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt ttaattaata
    21001 gaaggaggta agtaaatgat tttaaataca aaattatttg gacgtactta tcagtttaaa
    21061 ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa attagcaggt
    21121 cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc acacataaaa
    21181 ttggaggata taagaaataa tcctgcagtg gcatatgaag aagatgaagt aacaagaata
    21241 atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac agtgtctgaa
    21301 cttagagaat ggctattgga ttcaaatact acaagtcttg atataagaag aatatcaaga
    21361 ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat ggacttagtt
    21421 tatgcagcta aaaagataaa ggttactgct cactgtaata caactatagg agaacaagga
    21481 acattatcag caagacttca acctaatcat ccaacagacg acccagatgg aatacttgca
    21541 tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt aaatccagtt
    21601 gatgactctg ttgagagtgt tactaaagta ttaaaaagat ttgaagaagt aaaacaaaaa
    21661 tatcaaatac caactcaaac atgtgtattg gcacacgtta ctacacaaat ggaagcaata
    21721 agaaatggtg ctcctgcaga tttaatattc caatctatag caggttctga aaaaggaaat
    21781 gaagcatttg gatttaatgg cgacactata gaagaagcta gacagttagc tttaaaacac
    21841 ggtacagcta caggacctaa cgttatgtat tttgaaactg gacaaggttc agaattatct
    21901 tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgcta tggatttgct
    21961 aaaaagtatg aaccattctt agtaaataca gttgttgggt ttataggacc tgagtactta
    22021 tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg taaactacat
    22081 ggtttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga ccaaaatgat
    22141 atggaaaact tagccatact attaacaaca gcaggatgta cgtattttat gggaatacct
    22201 catggagatg atgttatgct taactatcaa acaacaggat accatgaaac agcatcactt
    22261 agagaaatgt ttggactaac agcaataaaa gaatttgatg cttggatgga aaagatggga
    22321 ttctctaaag atggtaagtt aacagagttg gcgggagacg catctgtatt attaggatag
    22381 gaggtattta atatgaatga gaaggattta aaagcattgg tagaacaatt agttggacaa
    22441 atggttggag aattagatac taatgttgtg tctgagactg ttaaaaaggc aactgaagtt
    22501 gtagtagaca acaatgcttg tatagatgat ataacagaag ttgatataag aaagcaatta
    22561 ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa aacacctgca
    22621 agattaggta taggaagagc tggtactaga tataaaacag aaacagtttt aagatttaga
    22681 gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga atttataaaa
    22741 gaaaataata tgtttgcagt ggaaacttta tgtaaagata aagatgaata cttaacaaga
    22801 ccagatttgg gaagaaaatt ttctccagaa actataaata atataaaatc taaatttggt
    22861 acaaatcaaa aggttttaat attagttgga gatgggctta gctcagctgc aatagaggca
    22921 aatttaaaag actgtgtgcc agctataaaa cagggtctaa aaatgtatgg tatagattca
    22981 agtgaaattt tatttgttaa acattgtaga gttggtgcta tggaccactt aggtgaagaa
    23041 ttaggttgtg aagttatatg tatgttggtt ggagaaagac caggattagt tactgctgaa
    23101 tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaagc aaaaagaaca
    23161 gttatatcaa atattcacaa aggtggaaca actgcagttg aagcaggtgc tcatatagct
    23221 gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa ataaagtcga
    23281 gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat atactaggaa ttaaaataat
    23341 ttcaaatata agtccagaaa tggcacaaaa actagaatta aaatcacatc acaaaagctt
    23401 aggtttaata actgcagact gtgatgatgt tacgtataca gcacttgacg aagcaactaa
    23461 agcttcagaa gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg caaatgcttc
    23521 aacaaaactt gctggtgaag tattaggaat aatagcaggt ccaagcccag cagaagtaag
    23581 aagtggtcta aatgcagtag ttgattttct agagtatgga gcaactttta taagtgcaaa
    23641 tgatgatgat tcaatagcat actatgctca ctgcgtatca agaacaggta catacctttc
    23701 agaggtagca ggaataagag aaggtgaagc attagcttat ttagtagcac caccacttga
    23761 agcaatgtat gcactagatg cagcaatgaa agctgcagat gttaagatgt gtgaattatt
    23821 tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc aatcggcttg
    23881 taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca atccaacagg
    23941 attttaagga tagttagatg gatgctatag gcttaataga agtaatagga tatgttgctg
    24001 caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta agagttgata
    24061 aggttggagc aggtattgtt actttaacaa tatgtggaga tgtcggtgct gtaaaagctg
    24121 ctttagaagc aggtgaaata gcagcttcca gagttggtac attaagaaca tcacatatta
    24181 taccgagaat ccataatgaa gtaacaaatg ctttattcaa aactaaagaa cctaaagtct
    24241 gtgaagtttc agaagataaa gaaaaaaact ttgagattac attggaaata gctgataatg
    24301 tatcgaaaaa tttatcagaa aaagaaaatg taattttaga tgtcaatgaa aacagtggag
    24361 atactgaaaa tttatatagt gatatagata aaacaaacaa aaaaattgaa acagttgatg
    24421 atagtttaac agaagctaat gaggaaaaaa tagaaaacac taatgataaa gaagtattgg
    24481 aacaagttaa aatagaaaat tccgattttg atagagatga cctatcaaag aacagtgtaa
    24541 aaaaacttaa agctatggct aaaaaattag attcttcaat aacttataaa gacttaaatg
    24601 ttcttaaaaa agaagaatta ataaacttag ttaaaaagct tagcagaagg gatagatagt
    24661 tatgacactt ttagataaag atttagtatc tatacaagaa gtaagaactc ttgtaagaag
    24721 atctaaagtg gctcaagaga aactttctaa aatgagtcaa gagcaaatag ataaaatagt
    24781 aaaagctgtt gtagatgcag catttaataa tgctactaaa ttagctaaaa tggcaaatga
    24841 agaaactgga tttggaaaat gggaagataa agtaattaaa aatacttttg catctatggg
    24901 agtttatgaa actttaaaga acacaaaaac tattggaata attggtgaag ataaagaagc
    24961 caatacgata gatatagcta caccagttgg agttgttgca ggtcttatac cttcaacaaa
    25021 cccaacatca acagtaatat acaaaactat aatatctcta aaagcaggaa atactatagt
    25081 tttctctcca catccaaatg caaaaaactg catacttgaa acagttaata taataagtga
    25141 ggctgctata aaggctggag ctccagagga ttcaatatta tgtataacta atccaagtat
    25201 agttggaacc aatgaattga tgaaacataa agatacaaac ttaatactag caactggagg
    25261 agaagcaatg gttagagctg cttactcttc aggaacacca gctattggag ttggaccagg
    25321 aaatggacca gcatttatag ataaatcagc aaatgttaaa ttagcaatca aaagaataat
    25381 agattctaaa acttttgata atggtgttat atgtgcatca gaacaatcta tagtaataga
    25441 aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat caaggtgcat atgttttaaa
    25501 tgaagaggaa agtgaaagat tagcaaaatt catattaaga gctaatggta ctatgaatcc
    25561 acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta gcagacttaa caaatgtacc
    25621 taaaaataca aaagttctag ttgcaagaga aaataaagtt ggtcacaatg tagcctattc
    25681 aagagaaaaa cttacaccaa tactagcgtt ctatgttgaa gaaaatgtag aagctattat
    25741 gaacagatgc agagaaatat tgttaaatga aggtgcaggt catacattct caatgcatgt
    25801 aaatgatgaa gaattggtaa aaagatttgc ccttaatatg ccagtatcaa gaatacttgt
    25861 gaatactcct tcagcacttg gaggaatagg tgcatcaaca aaccttgtac cagcactaac
    25921 acttggttgt ggtgcaatag gtggaagttc aacttcaaac aatataggac cacttgattt
    25981 aataaatgtt aaaagagtag cttatggaat caaagaaata gaagaacttg gaagagataa
    26041 atctcaagtt gaaaaatcaa tgtttgactc aatggataaa gaagaattaa taaatcttct
    26101 tgttcaaaaa ctagtcaaag aactagcata actaaaataa acaatgaaac ttatggctat
    26161 cgctataaat ttctaaaaat ataaactata aaaaactata aaattaaatt tttggaggat
    26221 aagattatgg caagtgcaaa cgcattagga atgatagaaa ctaaaggatt agtaggagca
    26281 atagaagcag cagatgcaat ggttaaagct gcaaatgtac aattagtagg aaaagagcaa
    26341 gtaggtggag gattagttac tgtaatggta agaggagatg ttggagctgt taaagctgct
    26401 acagatgcag gagctgcagc tgccgagaga gttggagaac taatatcagt tcatgttata
    26461 ccaagaccac actttgaagt agatgctata ttaccaaagg tatcagctga gtaatataag
    26521 aataattata aaatttaaat tttgattgaa aaagaggcta tctcaaaaat gagtcttact
    26581 aataaactca atgtattttg aggtagtctt ttttatacat ctaataggag atgtgataaa
    26641 atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg gaaaaaacaa aaataatata
    26701 actgaatttt atatagaaaa aggtcaaata ataactcctt ctgcaaaatc ttatttagct
    26761 gagagaagta ttgagcttaa atatgttgat aaactttcag atgtaaacaa tgaacctaaa
    26821 gaagttgtaa aagaagtagt taaagagaaa aaatatagat atactactgt atttggcgct
    26881 aaattggatg aaaaaccaga acatatgact caattaaatg gaaatctttt agtttttaaa
    26941 gaccataaaa gaataatatt gagaggaaaa atagattctc ttgaatcaga aatactaaag
    27001 gtacagatac tttgtcagaa actagatatg ccaaagcttg ttaaggaatt gcaagaagta
    27061 ttagactttg taagaaatat aatgagatgt gaagttttag atgaaaagct aggggacttt
    27121 aaacttttag gattaactcc tcaagaactt agagaacaat ctcactatcc taaaaaatac
    27181 tttggtatag gacatgaatt cccaagttat gaaatgggag aagtagtagt agctataaat
    27241 agtataagaa gtaatacacg agaggttgaa cttgcagcct atgaagcatt taagggtgag
    27301 tatggaaatg ttcacagaga agatttaata aaggcactta atagattatc gtcagtattt
    27361 tggataatga tatataaggt tagaactaat aagtataagt agttggagga cataatggag
    27421 aatctattaa atgaaatagt ggaagaagta ataactagag ttaaaaaaga agcatttata
    27481 gaagttgaag catcaggaag acacgttcac ttaagtagag aagatgtcga taaattattt
    27541 ggagaaggat atactcttac aaaactaaaa gacctatctc aaccaggtca atatgcatgt
    27601 aaggaaagag ttacaataac tggtcctaaa ggaagtataa aaaatgtagt tgtacttgga
    27661 ccatgtagaa atgaaactca ggtagaaata tctttaacag atggttcaac tcttggacta
    27721 aaagctccta taaaacaaag tggagactta gaaggtactt taagtattaa aatatcaaca
    27781 caatatggtg aagttgaact tgataagggg ttaatggttg ctaaaagaca tatacacatg
    27841 actcctaaag atgctgaaaa attcaatgta tgtgataaag agatagttga agctaaggtg
    27901 atgggtcaaa gacctttaac atttgatgat gtagtaataa gagtgagtga cagttttaaa
    27961 acttatatgc atatagacta tgatgaagcc aatgcatgtg gttattcaaa aggaactgtt
    28021 gctaaaataa taaagaaagc ataaatttaa cctactatat aaattacctc tagggaggat
    28081 ttaatatgaa ttatgataac cttgtagatt taataacgga agaaatctat aaaaaaataa
    28141 atagtaatga aataaaaata tctaataaac ctaaagctgt gattgtattt gaacaagata
    28201 acaataaatt taacttatta aaagatgaat ttgaaatagt agaatttgat aaaagtataa
    28261 gggaatgtga aatagtgata gtttcaagac tttgtatgag ggggctatcg aatatagcac
    28321 ttggaaattc aacaagtgat gaagaaagat ttatactaaa aatgattatg aagggcaaaa
    28381 aagtatatgt cttagatgaa ggaattgaat acaaaaaata taaggatact gcaccaaaag
    28441 cattatataa gaaatttatg tcatttgaag atgaaatatg taaatttggt gtagaaatta
    28501 taaaagactt aaatgttata actaaaaata agttaaatat aaagaaagaa ctagaaagta
    28561 ctagaggttc taaaaaagaa gatacaaaag ttttagataa agatgtttta aatttaacca
    28621 gtgtagaaag tgtaaaaata gataatgaat ttagtttaga tttaaggaat aaaaaactta
    28681 tatcggaagc tgacttaaga aaaccaacta taaatggagt taaaaacata ttagttaata
    28741 aaaaaagtat aataacacca ttagctgtag attttatgag aatacaccat ctcaaactaa
    28801 agaaactgta aggaggtaat tttatggata taggaaaagt tgtaggtaat gtttgggcta
    28861 caagaaaaga tgaaaaatta tgtggccaaa aacttttagt tgtaaaaatt ttaaaaacta
    28921 aagacacata caaggaaggc ttcatggttg cagccgataa tgcaggagca ggaaatggag
    28981 acttagttct tatatccaaa ggttcctcag ctagagagtc gattgaaaaa tctcatgttc
    29041 cagtagatgc aactatagtt ggagtagtcg attcgtttga ggtgtttgat gaataaaagt
    29101 ataggagcca tagagtttaa aagcattgct aaaggtatag aagtatccaa tgaaatgata
    29161 aagaaatctt cagttgatgt attgtactta aaaagtattt gcccaggtaa atttctaata
    29221 atagtaggtg gagaaaattc ttatataaat gaatgtgtag attatggaat aaaacttgga
    29281 gaaggatata ttgtagataa ctttgtaata aatgcaattt cacaagaaat attagatgga
    29341 tttaaaaata agtatcaaaa tctagatagt atagtctcta taggcgttgt tgaaagtagt
    29401 aaagtatgcg ctggaataaa aatgcttgat aagactttaa aatctggcga cttagtatta
    29461 gtaaaacttc aattatcttt tgctataggt ggcaaattag tatatatagt agcaggagat
    29521 ttaagtagtt tagaatatgc attaaaagaa agtgaaaatg tagtaagaga aaaagaagta
    29581 atatataaga ctgtaatacc atcagtagac agtcaaataa taaaaagtct aataaaataa
    29641 tggggggaat tatgagtata aacgaaatta taatctatgt aatggtagtc ttcatggtac
    29701 ttggagctat agataaatgt ataggtaaca aatttggtct tggagaacaa tttgaagaag
    29761 gtataatggc aatggggtca cttgcagttg caatggttgg tgttatatgt ttagcaccag
    29821 ttcttgctga tgtattaaga ccaattgtag taccagtatt taatatactt ggagctgacc
    29881 cagctatgtt tgctggaagt ttattagcta atgatatggg tggtgcgcca cttgcacttg
    29941 aacttgcgaa agaccctaat gctgggttat ttggtggatt aatagtaggg gctatgatgg
    30001 gacctacaat agtatttata ataccagttg cgcttggaat aattgaaaaa gaagaccaaa
    30061 aattcttagc aacaggaata cttgcaggta taataacaat acctattgga gcattcgttg
    30121 gtggattagt tgcaggattc gaggtaatga tggttcttag aaacttagtg ccaataataa
    30181 tatttgcagt agttatagca cttggattat taaaattcga aaatgctatg ataaaaggat
    30241 tcacatactt tggaaaaggt gtagtaatag ttataacttt aggacttgct gctgccatag
    30301 ttgaagcttt aacaggaata gttgtaatac ctggaatgaa accaatcagt gaaggtatag
    30361 aaatagttgg agatatagca atagttttag caggagcatt cccattagtg tttgttataa
    30421 caaaggtatt taataaacca ttaatggctt taggaaaagt tcttggaatg aatgatgtat
    30481 cagcagcagg ccttgttgca agtttagcta actgtatacc aatgtttggt atgatgaaag
    30541 atatggacaa tagaggaaaa ataataaatg tagcattctc tgtatcagca gcattcgtat
    30601 ttggagacca cttaggattt acggcaggat ttaattctaa tatgataaca ccaatgatag
    30661 ttgctaaatt agttggtggt ataacagcag tattgttagc tatggttatc gcaaataaga
    30721 cactaaagaa ggagaatgta taagatggat atatcaaata tagataaaaa tttaattgaa
    30781 acattagtaa gacaaataat agaagaaaaa ataagtggaa ctaaagacac agtagatttt
    30841 gttagaaata aagacattag tggaataact tctataaagt taccaactgt aaaagttagt
    30901 gaatctgata gattagatac agggaatcca agtgatgtag tttacacaaa agatttattt
    30961 acattagagg aaagcccaag attaggttgt ggtatgatgg aaatgaaaga aacaactttt
    31021 gattggactc taaattatga tgaaatagat tatgtaatag atggaacttt agatataata
    31081 atagatggaa gaaaggtttc tgcttcttca ggtgaattaa tattcatacc aaaaggaagt
    31141 aagatacaat tttctgtacc tgattatgct agatttatat atgtaacata tccggcagat
    31201 tgggcatctc aaaattaata aaaatcaagt taagttaata atcaaataaa taatttaaaa
    31261 tacaaactct taaataagca cgcatattta aaaaagctat gaattaaaat tcatagcttt
    31321 ttttataaag aatgttatat tttagacgta ttttttctat atttactggg agatatatta
    31381 tattttttat taaataatct aataaaatgc tctacatttg gataaccaat actattttac
    31441 tgataatctt ttccttatca ctaatcttac attttaaaat attattttta ctcgtaatat
    31501 tatcataaga atttgtttct tatttaaaac taattagaat tataaagttt attgccatgt
    31561 tattaataaa ataaatccag ttaaatcgag tgctagttaa agtaataaga aacttttaca
    31621 atggtttcct ttatcgattg aaataaaagt taatatggta taatatctaa agagagaatc
    31681 ttatcaatta gaatatgcat agaaacaagt ggcttaaaag gagacgttat atggaagaga
    31741 tagtaaagaa ggaacaagca agtatgaatg atattttttt gtatcttaaa gctaaatcaa
    31801 actcattata taaatttgta atattatata atgagtttat caataaacct aaagattatg
    31861 gaactgggga acttataaac atggttgaag tacatatgct aacagcgatt gaagaaaatc
    31921 caggaataag tccaactcag ttagctaaaa tatggaacag aactaaaggt gcaatatctc
    31981 aaactatatc taaattggag aaaaagggtt atataactaa agaaaagaaa gaaggaaatg
    32041 caaaaactat attactatat ccaaccacat caggagtaga gttaagtaag gcacataaac
    32101 tatatgacac catagatgtt acaagaacat ttgaatactt aatcaaggag tgtacattag
    32161 aggagataga tagtttttat aaagtaattg atttgtttat taatttatta gaagaatctc
    32221 cgcaggaaaa taatgattct gaaaaagtgt agctgagatt gaagttgaat aaagagaaat
    32281 agatattata gaagtagtac ttaagtacac attatataaa aatataatag gtataggatt
    32341 aaaaagttta gtggtttaaa gtttaaccac taaacttttt taatgtctat aatctactat
    32401 tatttaattt actaaaaata aaaaaactca ttatattaag atagaaatag aaaaataact
    32461 agaaaaatac tataatatat cagcttaata cagaaaaaag ttaaaaaatt tgagaaaaat
    32521 aaaaatgaaa acgttttata ttgacataga gaaaaagtag tgataccatt taaatatagt
    32581 ttagtagcta aactatattt aaattataat aactatttta gggggatgtt atgaatttaa
    32641 aacaattaag tgaaaaatac gaagaatatg taattcaaat gagaagagaa tttcataagt
    32701 atccagaatt atcttttaaa gaaataagaa caacccaaag aataagggaa gaattacaaa
    32761 aaataggggt cccttttgta tctattgaac caaatatcgt aatagctact atacaaggca
    32821 aaaatgaagg taagacaatt gcaattagag gagatataga tgcgcttcca atgcaagaag
    32881 attcagatgt tgaatacaaa tcagaatatg atggaataat gcattcttgt ggacatgatg
    32941 ctcatggagc tatgttacta ggacttgcac atatgctaaa tgatataaga aaagatttaa
    33001 aaggtagagt attattagtt tttcaagcag ctgaagaagt tggtggtgga cacaaggaga
    33061 taatacagta ctttaaggaa aatggaggac cggatagatt aatagctact catgtttggt
    33121 ccgatattga agctggtaaa atttctgttg aaccaggacc tcgtatggct ggtgggtctg
    33181 gttggagaat agacataaca ggtagaggag gtcatggttc tagaccagat caaagcatag
    33241 atcctataaa gccagcttgt gatatagttt taaaagtatc ttctatacca gttaatcata
    33301 taagtgtact agaacaatgt gttgtacatg catgtgcaat acatggagga actacaatag
    33361 gaaatgttat tccaaacaat gcagaggtaa taggtggata tagatatttt actgaagaat
    33421 caggcaaaaa agtgtttgac attataaagc aaatgagtaa tggtgttgga caagtttatg
    33481 gagtggatgt gaaggttact catactggag gcataggacc tgttatcaat gatgaagaag
    33541 cagttaagat ggctaaagaa atagtttcta atatagatgg attggagtta gattcttatg
    33601 agccaatatg tgcatcagat tgttatggtg aaatattaaa agagtattct ggcttttatt
    33661 gttatctagg ggtaggtaac aaagaaaaag gaataatata tgcacaacac catcctaagt
    33721 acaatataga tgaagatata ttaaagttag gttgcgaatt tatggctaaa tatgcagttg
    33781 aatttttaaa taaaaataat aactaaaata aatctaattt tataaatggg gggatgaaaa
    33841 tgcaaggtgc attaaaggaa aataagaaaa aaagtggtgg aggattttta ggatggattg
    33901 aaaaagttgg gaataaaatg ccacatcctc tagcattatt tacatatatt acactgatag
    33961 tagtagcatt atctgcaata gcaagctttt taggtttttc agcaacaagt cctgctacag
    34021 gaaagttaat aaaagttatg aacttaataa gtgcaaaagg tttagtacta tttatgcaag
    34081 agtttgttaa gaacttccaa aacttccctg tgcttggagt agttttagtt atggcagttg
    34141 ccacaggagt ttgtgaaaag acaggatttt tttcaactgc cataaaaatg agtttatcaa
    34201 aagttaaggg gaatgcggtt gtatttataa tagcttttat aggagtattt gctaatcaag
    34261 ctggtgatgc tgcttttgta ttagtaccaa ctcttgcagg agcaatattt tatggattaa
    34321 atagaaatcc attagctggt atattctgtg gatttgcatc agttggtggt ggatttgcaa
    34381 cagctgtaat tcctggggga tgggacgtta cgctaacgcc aataactgta tcagctgctc
    34441 aaactattca acctgcattt gatatgacat tattagctag ttattatgca ctatttgtat
    34501 ctgcgtttat agtagctaca gtatcaacaa tagtaacggt taaatttata gaacctaaat
    34561 taggtaagta tactggtaaa ccagaaggta tagatgataa tcaaggtttt gaggtcacaa
    34621 aagaacaagc aaaagcagca aagttagcag gttttacagt tttagcttat gtagcgttat
    34681 taattgcttt gtgtatacca gctaatagtt ttttaagaag tccagaaggt tctttaatat
    34741 ttggagcacc acttatgtct tgcttacagt tttttatagt aatactattc ttcttgccag
    34801 ggattgtgta tggaatgagg gttggtaaaa tcaagactgt aaaagactta aatgatatat
    34861 tatgtcaatc aatggcagca atggcaccgt ttatcgtact tgcaatagtt ataggtcaat
    34921 tcttaacgct attctcagtg tctaatttag cacaggtact agctataaaa ggtggagcat
    34981 tactcaactc attgccacta ccaccacaag ctataatact gctattctta gtactagtag
    35041 cgtttataaa tatatttgtt ataagcggaa gtacaaaatg gatgatattt ggaccagtat
    35101 ttgttccaat gttaatgcaa ttaaacatac atccagcatt tactcagttt gtatatagat
    35161 taggagattc tgtaaccaat catttatcac cattaaatgc attctttata atacttttag
    35221 caacagtcca aaaatacgat aaaaatgcag gtatgggaac tatattctca gctatgatac
    35281 cttacactat aggttacttt gtagtacttg cagttttagt agtagtttgg atgacaatag
    35341 gtataccagt aggaataggt ggacaagttt ggttataaaa catatttaat aattttggga
    35401 ggaaaaaaaa tggaaacaac tgaaataaga tacaattttg atgaagtaat agatagaagt
    35461 ggaacaaact gtcttaaata tgatcttaag agtcaattta tgccagaatc tccagaagat
    35521 gcactaccac tatgggtagc agatatggat tttgcatgtg cccctgagat aattaatgca
    35581 atgcatgaaa gaatagacag aaaaatattt ggatatagct ctcaacaaac tgatgattat
    35641 tatgaagctg tatgtggatg gtttaagaga agatttgatt ggaaaataga aaaagagaat
    35701 atattcttta gcccaggggt tgtgcctgcg ttaggatttt tcacacaaat attaacacaa
    35761 aagggtgatg gtatcataat agaaaagcct gtatactatc cttttgaaga taaaataact
    35821 aacaatgaaa gaaaagtagt taatagtcct ttaaagtttg aagatggtca ttattctatg
    35881 gattatgatg gatttgaaga attagctaaa gatgaaaata ataaggtgtt tatattatgt
    35941 agtcctcata atccagttgg tagagtatgg aaaaaagaag agcttagaaa aatagtagac
    36001 atatgtaaga aatatgattt gtggataata tctgatgaaa tacattgtga tattattcgt
    36061 aaaggtgaaa agcatatacc attagaagta gcatgtcctg attataaaga tagaataata
    36121 acttgtacag ctccaagtaa gagttttaac ttagctggta tgcaattatc aaatatagta
    36181 atcaataata aggaattaca agaaaaatgg atgcttgaaa cagattctaa attagctata
    36241 ttcctaccta atccattcgc aatagttgct actaaagttg cttataatga ttgtgaagat
    36301 tggatgaatc aagtaaatga gtatatagat ggtaatatta aatatgtaga agattttgtt
    36361 aatgagtata tgcctaaagt aaagataata aaatctcaag gaacttactt agtttggtta
    36421 gactttagag ggtatggatt agatgcaaaa cagcttgaat atgtaatgct taacaaggcg
    36481 aaggtattgc tagatgaagg atacatattc ggagaagaag gagcaggatt tgaaagaata
    36541 aatgttgctt cacctagaac aattatagaa gagtgtatga atagaataaa atgtgcattt
    36601 gaaggattat aatagtaata tctaaataat atatttgtgt attttaaaaa aagactatgc
    36661 taaaaaaata tttcaaagca tagtctttta aagttttatg atgagtttaa aaaatttcaa
    36721 aacgttacta ttcacttata tgtttatatt agaaataatt ccacaatata ctcattttct
    36781 aaagttgcac ttttatacac cttgcttcac caatatcatg tgtaaccaaa atagtagact
    36841 tattctcatt cttaataata ctataaacat catcacaaac taataatcta gtctgataat
    36901 caagagctga aaaaggttca tctaaaagta gaatatctgg atttacagaa agtgttctaa
    36961 taagcgcaac tctttgtctc atacctccag ataattcttt tggatacata cttctaaaat
    37021 cccataatcc ataagtcttt aaaaggcttt caactctatc taaagatttt ttatcttttt
    37081 tgccttgaat ttccaatcca atagttatat tatccattat atttctccat tcaagcaaat
    37141 tatctttttg aaacatatat ccaatatttc cagtaatctt tatatcacca ctagttggtt
    37201 ttaaaagatt agtaagaata tttaatattg tagatttacc acttccagaa ggaccaagca
    37261 aagttaatat ttctccttct ttcaagttaa aattgacatc ctttaatact tcaagctcgc
    37321 cttccttagt gtagaagttc atatttatat ttttaacttc tactatgttg tcattcatta
    37381 tgccaccccc tataactttt agctcgtata tattatgtta ttaacaatat gacctatttg
    37441 taccattttt cataaatata atataaatat tttgtttatt tacgtatttt cttagtaact
    37501 tgtacgtata aattatagat aaataaatta taaggtaggg gataaatttg agtaacataa
    37561 taacgaattt aatagagtca atatttacta atccaataac tatattgttt ttacttgcaa
    37621 taactgtgta ttctgttttt aaaataatag aaaataacag agtatattca tttgtaagtt
    37681 caaaattaga cgaaatcaat agagactata agacaagtga gttttataaa aaggtaaggg
    37741 atgactacta tacatatagt aaagaaaatc cttatgcaga cgtaaatata acttcattta
    37801 tagaggaagt tgtatctgat ttaaagcata ataatttgcc attgttagaa aaaattagaa
    37861 gtataaaaaa ttcatcttca ataagtatat tacttggggt tttaggtacg tttgttggtc
    37921 tttctacaat gcttttatgt gttgatacta aagacattat aaattcactt ccttcaacta
    37981 ttagtagtat gcaaactgca tttacaacta gtatatttgg agttgtattt tctctaatta
    38041 taggttattt tactaagata aaagattgtg aacatgtttt gatacaaata atgttaaaat
    38101 ctgaaaattt actaacatct gaaataactc attttaagtc agaaagaatg gatttaaaag
    38161 tagaagaggt aaaaaataca ataaaacaaa taagtaagtc tatagaagct attgaaaaat
    38221 ttgataaaat atctaaagat ttaaatgact ttaatgatga atttatcagt ggtatagaag
    38281 ctttaaaaag ccttttagaa ggttctcaaa gttctattaa gacatttgac cagagcgtaa
    38341 gaaaattaga taaacagttt aatattttaa atataaaatt tgtaaagctt tttgataaat
    38401 atgataatca agataatata aataaagaga ttttatttga tataaaagaa tcttcaaaaa
    38461 atatatacaa tgccactgaa agccaattca aaattagaga ttatataaaa aatataaatg
    38521 caggatttgc tctatatgaa agaagtgctc aagatttatt aactaaatta atgacccatg
    38581 aaaataaaat ctctcaaaat caaaaaatcc ttttagatga aaagtttacc ttagatgact
    38641 caataaaaaa tctctcaagt attattgaaa acttttctaa tgacctacaa gttaaactgg
    38701 atatgatgtt tgaaaattct ttagatattc aagataagtt agatgttatg tttaataact
    38761 cttttatgaa tgatgaagtt cctcttgata gtgaagaatt atttaaggat gatgttaata
    38821 atgtatttaa tccttttagt gaagaaattt atgagataga ggataaagaa ataaaggtca
    38881 taggtgagga tgagttaaat gaataataaa tatagaagaa ctgttaacag agaatttgaa
    38941 aagagtagct tttggccaac atttacagat ttattatcta ctgtattgat ggttgtaatt
    39001 cttatcttat ttagctcaga aagtatttca ggttctgttg aacaagattt agctaagaat
    39061 gtcaatgctt ctgttgaaga aacttttaaa aaaagtggaa tacctgtgaa ggtagataaa
    39121 tctaatgggc aagtaacttt tggtgaaaaa accatgtttg atgtagatag tgatgtttta
    39181 aaaccagagg ctaaagaaat gctaaaaatg tttgttccaa agtacataga gactatttat
    39241 aaagattatg gtgactatat atccaaaata gttatagaag gtcatacaga tgatgtggga
    39301 agttatatat acaacttaga tttatcgcaa agaagagcat atagcgttgc taaatttata
    39361 gtgggagatg aaataggtga ctataaatac aaagataaag tgactaagca tattattgca
    39421 ataggaaggt caaaagctga actcatcaaa aatggtgaca atagcgtgaa tagagatgca
    39481 tctagaagag tagaactaaa atacgaaata aatattaatc aaaataaata attaaatttt
    39541 tataaaaaaa aagaaggcag ttggtgtgag ctttaagcct tctttaagga aaaagtttat
    39601 ttatttttgt tgatacttaa catattatag tttttagaag cagtttgcaa tatattaaac
    39661 gtaaatggtc gtttaaaatg cataactgga tactactgat gtaaaatatt tcattttata
    39721 taatataaaa attatacagt atcaattttc tatattattg tactataatc tattatttaa
    39781 aatattatgt aaaaaaatat cataaaaacg catatcatgt tataattact agagtattat
    39841 gaatatggag gcgtagtttg tgatagaaat aagtataaaa aataaaaaaa attctaaaat
    39901 taaaactttg atacttttat tgatagtatc tatatcaatt tatttaactg gttgtactac
    39961 attagataat ggaaataatc aatcaaataa taatgattct ttgtctagta gtatatcaag
    40021 tgataagaat gtaaaaattc attttattga cactggaaat agtgatgcaa tattgattca
    40081 agatggtaaa acttttatat tgatagatgg gggagataat gatgatgagg gattaatggt
    40141 agattaccta aacaatcaag gtgtaaaaga tattaaatat cttatagcta cccattctca
    40201 tgcagaccat ttaggtggac ttgattctgt tgtcaaaaac tttaatatag aaaatgtttt
    40261 tgtatcgaat ggttcagcag aaacaaagag ttatagggac tttataaatg ctttagcaaa
    40321 taagggttta tccccaagtg taccgcttga aaataataag ttctatttag aagattctta
    40381 ttttgaagtt ctaaatacaa atgggggaga tactactaat gaacaatctc tagtccttgt
    40441 atatactaat gggaatgata aagttttatt tacaggtgat gctgaagaag gtaccgaaaa
    40501 agaaatactc cctaagcttg agaaagtaga ccttttaaaa gtagctcatc atggttctcg
    40561 tagtagttca tctcaagagt ttttagataa agtaaatcct gaatatgcgg ttcttttagt
    40621 aggcaagggt aattcatatg gtcatccaca tcaggagaca atgaataaat taaaaaaaat
    40681 gggagtaaaa gtacatagaa gtgatgagtg ttcagatata atatttgaat caacaggtga
    40741 tggagtattt acaagttgta aagatggaag ttataataaa ggcgttagag aagatggaaa
    40801 ctctggaaaa tcaaacagta atacaagtaa aaatgattct tttaaaaata aacaaaatac
    40861 atccaattca gaagaaatag tgtattttac tccaaaaggt aagagttatc actctacaaa
    40921 aaattgtagt gggctttcaa gaagtaaaaa aatattatca ggcacaattg cagaaagtaa
    40981 gaaaaatgac ccatgtgata tatgttatgg aaaataacaa aaaaacaacc aatttatcta
    41041 taaagcttct gaactttaaa tcatttaaaa aataaaataa atgcataaaa aaataagcta
    41101 taatcaatag ataacacatt ttatctatac gaatagctta tttttttaag tattttttaa
    41161 tagctattta ataactctaa atacaccagt tacaatacct acaatttcaa cttctgagtc
    41221 attgagcata attggttcca taaaatcatt ttctggctga agtcttatta aatttccttc
    41281 tttaaaaaac ctcttaactg tagcagattc accatttata agtgcaacta ctatctgaga
    41341 atttaaggct gtattttttt tgtctactac aacgtaatct tcatctaaaa ttcctgcatt
    41401 aatcatactt tcgcctttta ctcttaatac aaaattgtta ctgcccttta ctaaactggc
    41461 agggaatgga atgtattcct ctatgttttg ttgagctaaa atgggttctc cagctgttat
    41521 ttgacctact aaaggaagct ctattatttc ttgattagct ccagaaacat catttacttt
    41581 actacgttct aaaacttcaa tagctcttgg tttagtaggg tcctttctta tgtatcccag
    41641 tttttcaagt ttatttagat gagagtgcac agttgaagta gatcttaacc ctacagcagt
    41701 acatatttct cttacagcag gtggataacc ttttaatatg atttgagact ttataaattc
    41761 caatatcaag acttgctttt cagttagatc taaatacata acatcactca tttccaaaca
    41821 tattttgttt ttatttccat acactttata tttttaatta taacataatc catttatatc
    41881 tgcaaacatt tgttcctgat ttttaatcgt cctcaatcca ttcaaaattc ttgactatat
    41941 cacgttttac atttttctta tgagctgcat aaagctgagt agttgtgaca ttatcatggt
    42001 caagtaagtt ttgaacatca tatatagaaa atcctgtttg gattagagaa gttgcagccg
    42061 ttgctcttaa tttatgggga ctatatccat tgtctctagt agtatcaagt ggaatagatg
    42121 tatatttttt taccagtgtt cttatagcct ttgctgtaat tctcttattt tgaagagaca
    42181 aaaataaagc atctttttct tcatcattta atagttcatc tcttgttctt tcgttttgca
    42241 aataatcttt tattacatgt tcacaagtat gatttatagg cattaaaact tctttcccac
    42301 gttttctata tattttaaat tcacctcttg aaaaattaaa agaggagata ttgagttctc
    42361 taagctcatt taatctaagc ccgtatgtaa caaataatgc tagtatagct ttgtcacgta
    42421 atttagtttt tctccaatat accttttctt tctctgtaag cccttcacct gtttctactg
    42481 attcaagcat cttagcaact tcatctatct caaggcgctt aatagcatct ggctgaggtt
    42541 taggaagttt tattggattg aatccatcag ttatattatt atctatctga gagtttctgt
    42601 ataagaattt aaatagagta gagatggatg atttttttct tgctaaagct ctattgttat
    42661 tttcaaaaat caatgtgttt ttttctgtat ttttgtaata tctactgcaa taatcaccta
    42721 agaataaatt tatatctctt gattttattg tattaaaatc atcttctgta atatctttta
    42781 cacaatctgc atttgttaat tctttggttt caatcaaata tgaacaaaaa aaattaatat
    42841 cttctaaata agcaagtcgt gtagaaactg caacagaacc ttttaaatat ataaaataat
    42901 ccttcataaa tacaggaagt ttattttcca aaagtagaca tttttctatg agttcatttt
    42961 ctttgataac aatattatca ggtttatctg atttattatg tacttttata attttcttat
    43021 cattattcaa aattaaacct cctaaaacta aaatataaat cttttatatt attttttgat
    43081 atttatacca agt
//
LOCUS       DAGQVA010000027        42791 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.027, whole genome shotgun sequence.
ACCESSION   DAGQVA010000027 DAGQVA010000000
VERSION     DAGQVA010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.027"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            190..1266
                     /locus_tag="MIV85_001640"
     CDS             190..1266
                     /locus_tag="MIV85_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBY2960981.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1369..2211)
                     /locus_tag="MIV85_001641"
     CDS             complement(1369..2211)
                     /locus_tag="MIV85_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBY2960982.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2395..2967
                     /locus_tag="MIV85_001642"
     CDS             2395..2967
                     /locus_tag="MIV85_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2960983.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3130..3402)
                     /locus_tag="MIV85_001643"
     CDS             complement(3130..3402)
                     /locus_tag="MIV85_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960984.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3516..4388)
                     /locus_tag="MIV85_001644"
     CDS             complement(3516..4388)
                     /locus_tag="MIV85_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBY2960985.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4684..7791)
                     /locus_tag="MIV85_001645"
     CDS             complement(4684..7791)
                     /locus_tag="MIV85_001645"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBY2960986.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGAKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7884..8116)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8291..8818)
                     /locus_tag="MIV85_001646"
     CDS             complement(8291..8818)
                     /locus_tag="MIV85_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBY2960987.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8853..9638)
                     /locus_tag="MIV85_001647"
     CDS             complement(8853..9638)
                     /locus_tag="MIV85_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBY2960988.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYERAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9648..9905)
                     /locus_tag="MIV85_001648"
     CDS             complement(9648..9905)
                     /locus_tag="MIV85_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBY2960989.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9924..10382)
                     /locus_tag="MIV85_001649"
     CDS             complement(9924..10382)
                     /locus_tag="MIV85_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBY2960990.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10422..11126)
                     /locus_tag="MIV85_001650"
     CDS             complement(10422..11126)
                     /locus_tag="MIV85_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBY2960991.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11136..11771)
                     /locus_tag="MIV85_001651"
     CDS             complement(11136..11771)
                     /locus_tag="MIV85_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960992.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVNTLVLKNEKVDAK
                     IHVKGSIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IIVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12152..13192
                     /locus_tag="MIV85_001652"
     CDS             12152..13192
                     /locus_tag="MIV85_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2960993.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13655..15010)
                     /locus_tag="MIV85_001653"
     CDS             complement(13655..15010)
                     /locus_tag="MIV85_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBY2960994.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15036..15305)
                     /locus_tag="MIV85_001654"
     CDS             complement(15036..15305)
                     /locus_tag="MIV85_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBY2960995.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15595..17565)
                     /locus_tag="MIV85_001655"
     CDS             complement(15595..17565)
                     /locus_tag="MIV85_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2960996.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGEDFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENNNNENDNSD
                     EKQPNTPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLS
                     SKSVFGTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIF
                     LFCILTPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17748..19223)
                     /gene="spoIVA"
                     /locus_tag="MIV85_001656"
     CDS             complement(17748..19223)
                     /gene="spoIVA"
                     /locus_tag="MIV85_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBY2960997.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19395..20690)
                     /locus_tag="MIV85_001657"
     CDS             complement(19395..20690)
                     /locus_tag="MIV85_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2960998.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSVINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASVA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENATKVS"
     gene            complement(20874..22283)
                     /locus_tag="MIV85_001658"
     CDS             complement(20874..22283)
                     /locus_tag="MIV85_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBY2960999.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(22335..23474)
                     /locus_tag="MIV85_001659"
     CDS             complement(22335..23474)
                     /locus_tag="MIV85_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBY2961000.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23793..24443
                     /locus_tag="MIV85_001660"
     CDS             23793..24443
                     /locus_tag="MIV85_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2961001.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAE"
     gene            complement(24600..25619)
                     /locus_tag="MIV85_001661"
     CDS             complement(24600..25619)
                     /locus_tag="MIV85_001661"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBY2961002.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNIIISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25650..26264)
                     /gene="plsY"
                     /locus_tag="MIV85_001662"
     CDS             complement(25650..26264)
                     /gene="plsY"
                     /locus_tag="MIV85_001662"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBY2961003.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(26299..27618)
                     /gene="der"
                     /locus_tag="MIV85_001663"
     CDS             complement(26299..27618)
                     /gene="der"
                     /locus_tag="MIV85_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBY2961004.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27652..28980)
                     /locus_tag="MIV85_001664"
     CDS             complement(27652..28980)
                     /locus_tag="MIV85_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBY2961005.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(29218..29418)
                     /locus_tag="MIV85_001665"
     CDS             complement(29218..29418)
                     /locus_tag="MIV85_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961006.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29420..30352)
                     /locus_tag="MIV85_001666"
     CDS             complement(29420..30352)
                     /locus_tag="MIV85_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBY2961007.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30397..31329)
                     /locus_tag="MIV85_001667"
     CDS             complement(30397..31329)
                     /locus_tag="MIV85_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBY2961008.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31384..32673)
                     /locus_tag="MIV85_001668"
     CDS             complement(31384..32673)
                     /locus_tag="MIV85_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2961009.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32702..33394)
                     /locus_tag="MIV85_001669"
     CDS             complement(32702..33394)
                     /locus_tag="MIV85_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961010.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33409..34170)
                     /gene="pgeF"
                     /locus_tag="MIV85_001670"
     CDS             complement(33409..34170)
                     /gene="pgeF"
                     /locus_tag="MIV85_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBY2961011.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(34167..34628)
                     /gene="nrdR"
                     /locus_tag="MIV85_001671"
     CDS             complement(34167..34628)
                     /gene="nrdR"
                     /locus_tag="MIV85_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBY2961012.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34650..34913)
                     /locus_tag="MIV85_001672"
     CDS             complement(34650..34913)
                     /locus_tag="MIV85_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBY2961013.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(35017..35790)
                     /gene="sigG"
                     /locus_tag="MIV85_001673"
     CDS             complement(35017..35790)
                     /gene="sigG"
                     /locus_tag="MIV85_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBY2961014.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(35882..36604)
                     /gene="sigE"
                     /locus_tag="MIV85_001674"
     CDS             complement(35882..36604)
                     /gene="sigE"
                     /locus_tag="MIV85_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBY2961015.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36629..37501)
                     /locus_tag="MIV85_001675"
     CDS             complement(36629..37501)
                     /locus_tag="MIV85_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBY2961016.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(37792..39066)
                     /locus_tag="MIV85_001676"
     CDS             complement(37792..39066)
                     /locus_tag="MIV85_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBY2961017.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39350..40507)
                     /gene="ftsZ"
                     /locus_tag="MIV85_001677"
     CDS             complement(39350..40507)
                     /gene="ftsZ"
                     /locus_tag="MIV85_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBY2961018.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40697..41050)
                     /locus_tag="MIV85_001678"
     CDS             complement(40697..41050)
                     /locus_tag="MIV85_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBY2961019.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(41149..41823)
                     /locus_tag="MIV85_001679"
     CDS             complement(41149..41823)
                     /locus_tag="MIV85_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBY2961020.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(41828..42526)
                     /locus_tag="MIV85_001680"
     CDS             complement(41828..42526)
                     /locus_tag="MIV85_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBY2961021.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42549..>42791)
                     /locus_tag="MIV85_001681"
     CDS             complement(42549..>42791)
                     /locus_tag="MIV85_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HBY2961022.1"
                     /translation="LNYLKEEGIYRKINYVNLKKESNIEILTRSNIKILLSNDDNLDY
                     NISRVSKILIDLQNKNTNGGTINLNYGKLAVYSPEG"
BASE COUNT        13375 a         7727 c         4631 g        17058 t
ORIGIN      
        1 attactttta tagaattttc acaataaaaa gtcattttac ttccgtattt aatgcaaaag
       61 tagaaattaa acttaatata aaaaatatat aacaaatttt ttttatattt ctagaagaaa
      121 agtatactct tttttgttta ataatgctaa aattgatttg tattgaattt tgattaggag
      181 gaaattatta tgaaagctca aagattaaat gctgtacttg aacaaatgaa aaaagatgat
      241 atttctcaaa tgttagtaag tgaccctact tctatatttt atcttacagg agtactaatc
      301 catccaggcg aaagactatt agcattatac ttaaatttaa atggcaataa taaattattt
      361 ataaatgaat tattcccagt ttcagaagat ttaggtgttg aaatggtttg gtttaatgat
      421 actcaaaatc cagtagaaat aataactgaa catatagaca aaaatgctac tatgggtgtt
      481 gataaaaact ggccagctag attcttatta aacttaatag aattaggtgg aggaagtaag
      541 tttgtaaatt catcttatat aatagatact ttaagaatgt gtaaagatga agaagaaaaa
      601 gagttaatga gaatagcttc aaaattaaat gacaaggcta tggaacaact taaagctact
      661 gtttctggtg aacttacaga aaaacaactt gttggtaaat tatctaaaat atatgaagac
      721 ctaggtactg atggattttc atttgaccct attataggtt ttggacctaa tggagctaat
      781 ccacatggtg aacctggaaa tgcacttgtg aaaccaggag atgcaataat cttagatata
      841 ggttgtataa aagataacta ttgtgctgat atgacaagaa ctgtattcta taaagaaata
      901 cctgaaaaag gtagagaaat atttgaaata gttcttgaag ctaataagag agctgaagct
      961 attgtaaaac caggtgttag attctgtgat atagatgctg ctgctcgtga ctacataact
     1021 gaaaagggat atggacagta cttcactcat agaactggtc actctatagg acttgaagtt
     1081 catgataaag gagatgtatc ttctataaat acagatactg tacaaccagg aatgatattc
     1141 tctatagagc caggtatata tttaccaggt gagttcggag ttagaataga agatttagta
     1201 cttgttactg aagatggttg tgagatatta aacaaacatg acaaagaaat atgtgtagtt
     1261 ggttaattct aaaatcaatt tgataaaatt aaaaagccat ataaaaatgt tttaaacatt
     1321 tttatatggc tttaatttct caatctatga tttatttcaa tccattattt atattgcagt
     1381 tattaagatt gcaccctttg aagtatatgt ccccatcact gaaccaattt cacagattac
     1441 aacatctttg tattttacat ccttttccat aacttccctt accttttgag ccttttctgg
     1501 gcaattagca tgtcctataa ataaaacctt ttcttcttta tctttaattt ttgactctac
     1561 taaagtaatc agctttttca aactgtttcc ttcacctctt gccttatcta taggagttac
     1621 aacgccatct gcaacttgta ttatcgcctt aaaatttaag gtatttataa tttttcctgc
     1681 tattggattt attctaccac ccttaatagc attttctaaa gtttcaagtg ttccaaaaaa
     1741 tggaggatta tctttatatt tatttattat tgaaacaatc tcttcaattt cttttccttc
     1801 ttttattaat attgctgctt ttaacactaa ttgtcctatt ccaattgacc cactaagtga
     1861 atctataacc tcaactttct tgttatttcc ttccttttca aacatatctt ttgctaaaag
     1921 tgcactatta taagtcccag ataatcctga acttatatta atcactaata cactttcttc
     1981 ctgacaatgg tatgcttcta aaaatttatc aggagaagga catgatgttt ttggtagtac
     2041 tttactctca ctcatttttc tatagaaagt ttcattatct atttcctttc cagatatata
     2101 actttcttct ccaaaagata catttaaacc tacaacttct atgttgtatt tttctattat
     2161 atcatcaggt aagtcacatg cactgtccac tatcaatttt attttatcca tattaacctc
     2221 actataagat attattttat ttattcagtc ggtcgtacga ccgatttaat tattatttta
     2281 tatattgaat gaaaaaaagt caatagatat agattctcgc tttattgaca ataaatatcc
     2341 ataagcttat aatgttatta atttgttata aatatacatg gaaaggtagg ttttatgaaa
     2401 acaaataata tgaaacaggc tattttatca tctgcaacca atttaatagc caaaaatgga
     2461 gttcaaaata ctagccttgc tgatattgca aaagatgtaa atataagtaa aggtactttg
     2521 tattatcact acgcatctaa agatgatatt atatatgata ttgcggatac tcatttagaa
     2581 gttataacta gtgctatact aaactgtgta aaaaatgtca aatcaaaaaa ttctcaaata
     2641 gaaatggtta acttaatctt agagaaaata tctactatag aaagtcgtgg tagggtacat
     2701 atgtatctta tttgtgaggc aattacttca aataatgatt taaaggaaag aataagatta
     2761 aaatatattg aatggagaac tactcttaaa tctgaaattg ttgaatcact agaaaaatat
     2821 aatagtagcg aaaatgaaca ggatgctgaa tcattttctt ttttactcat gtcaatagtt
     2881 gatggtttag ttgtccaaag tttattaaaa acagaaaaaa taccttatga aaatatagct
     2941 tcttttttag ttaatcattg gatttaaact taatacttag ataattaata aaagtgaact
     3001 atttaagtta tctactttaa cagttcactt tcttatttat tctcaataat ttttacttaa
     3061 aacattcaat ttttatttaa accttcatgg aatcacaaaa taaaaatctc ttataaattt
     3121 aaaatgtttt tatttatgtt catgtgtatg cccatctgaa tgttcatgac catgtgtatg
     3181 tgtatgctca tggctatgct catgagtacc tgaaaaacca tcatcatgat tatggtcgtg
     3241 acctacacca tttacatgct catgttcatg cccatgactg tgagaatgtt gatgtgaatg
     3301 ttcatggtta tctcctccac agcatccttc tcctccagtc ccacaacacc cacttgtatg
     3361 tggattatga tgatttctta ctacaaatct ctctcttaac ataattctta tacctcctag
     3421 tatattattg agtacttcat gtaccccatt aactacagta tacatctaac taggtataat
     3481 ctcaatacat atggcatttt ttaacatata taatcttaaa gaaatttatc cttaaaacct
     3541 ccacctttta cttcttcaac gttattgaca gaaataaaag cttcactatc catatcataa
     3601 attaaatctt taaatttacc tatttcattt gcagatatta tacaataaat catctttttc
     3661 ttattttgtg tatatgcacc ttctgcctcc aaaaaagtga ctcctctacc cattttattc
     3721 attatcactt tggatatttc atcatattta tttgatatta aaagtataga tttttttcta
     3781 tcaaagcaat cttttcctat atccatagta aaagaaatta tatacattgt aattaaagtg
     3841 tacatcacca atttagctcc aaataaaaaa gctcctgcac atactacaaa aaaattaata
     3901 aataaaaatg tatttttcat aggtatatca tactttcttt tcattatggc tgctattata
     3961 tcaagtcctc cagcagtagc tcttgcttta aaagttaacc ccatacctat accagttaat
     4021 gcaccaccat aaatacactg tagcatagta tcatctattg ggaaatattt agcaatatct
     4081 tgtgttagcc ccagtgctag agaaaatagt aacatattga caaaacttat tagcaaaaat
     4141 ttattatcaa aatactttct agctataata aatattggta tgttcatcaa gaaacttgat
     4201 attccctgat taataccaaa taatttgtat aatataacac aaattccagc tactcctcca
     4261 cttaataact tggctggtgc tagatataaa tttattccta aggttgatag aatcataccc
     4321 aatataatca gacaatattg taaaaatata ttattatcaa tacttagctt tttactttca
     4381 ccatacatca aaacgcaccc ctttgcataa taaataaacc accctgcata acacacgata
     4441 aatttacaaa taaatttatc agaagtagtt tcctaaaaat attattcatc ctcacttaaa
     4501 cgtttattca ttaatattct atcacatgac ataaataatt tatatgattt atatagattt
     4561 atttattgta aattttggaa tattaaaaca ttttattgaa tagataatta tattacataa
     4621 aaaatcccta tagaaatcta taaactaatt tctataggga ttttggttaa ctaactatta
     4681 tttttatttt tttataactt ttatacctgt catatggtca tttaagtttt gttcctctaa
     4741 agatttatca tctactctgt ttatttctaa agctaaagtt tcagacttga tatattcatt
     4801 aaaatggtca acagccttag caatttcatc atcaccacag tattctatta ctatattatc
     4861 taatacttca aagttattag attttcttaa ttgctgtact ttagatataa attctctagc
     4921 ataaccttca ttaatcaact cttcagttag cttagtatct agtataacaa aaagattgtt
     4981 ttcaacagat acattaaatc cttccttagc agttatacct attaatacta aatccttatt
     5041 aaattcaaaa gcttcaccat ctaaatcaac tgttaaagtc tcaccttttt caagtttatt
     5101 agcagtttca tgagcattta atttacttaa tgctccaacg aataaattca tcttagcacc
     5161 taataatggc cctgcttcct taaagtttgg ttttaaacta aagttcatat actcatctaa
     5221 atccttagca aatattacct ctttaacatt aagctcttct tttattaaat caactacatc
     5281 acttattgta tcttcaaact taccatctac taacactttt tgtaatggtt gacgaacttt
     5341 tattctttct acttctcttg aagctctacc taaagtaact aagtttttag ctaaatccat
     5401 tttttcttct aatttagtat ctactaactc ttcattacat ttaggatatt cagctaaatg
     5461 aacagatact tctcctgtta agtttctata catttcttct gacatatatg gtgcaaatgg
     5521 agctatagct ctacaaagac catgtaacaa ttcataagtt gtattgtaca ctgctttttt
     5581 atcttctgtt aattcagttg cccagaatct tcttcttgaa cgtcttatat accagttaga
     5641 taaatcatca tttataaaat cttgtatcat tcttaaagtt ttatttaact caaatatagc
     5701 taaattttct tctacatctt tcattaaatt attgaactta gataatatcc atctatcaag
     5761 ttctggtcta tctttatatt ctacaaaaaa ttcagttgga tttatatcat ctgtgtttgc
     5821 atataaagta aagaagttat atacattctt catagtacct ataaatttac tttggatttc
     5881 ttttaatcca tccatatcaa atttagttgg agtccatggt ggagaaacat atagtaaata
     5941 ccatcttaat gcatctgctc catattggtc aaataattcc attggattta ctgtatttcc
     6001 tcttgattta ctcattttct taccatcttt atcaagtaca aggtctggaa ctaaaacact
     6061 cttatatggt gcttttccta atacaaatgt tgatactgca agtaatgagt agaaccaacc
     6121 tctagtctgg tctatacctt ctgatatata gtcagctggg aacaattggt caaagttttc
     6181 cttattttca aatggatagt ggtgttgagc aaatggcata gccccactat caaaccaaca
     6241 gtctataacc tctgttactc ttgtcattgg ttttccacat ttttcacatt ttaagtgtat
     6301 atcatctaca tatggtctat gaagttcaac tgtttctgga tttacatctt ctatagcttt
     6361 ttcagctaat tcagctcttg aaccaactga atctgtatga ccacattcac atctccatat
     6421 aggaagtgga gttccccaat atctagttct tgatattgcc cagtcattta gattttctaa
     6481 ccagtttcca aatctcttct ctcctacaaa acttgggaac cattttacac cattattatt
     6541 ttctattaat ttatctttaa gtttagtcat ctctatatac cagcttggtt ttgcatagta
     6601 tactaatgga gtttgacatc tccagcagtg tggataatta tgaactactt tttctttgct
     6661 atataattta ttttcagaag ctagccattt tattatttca acatctagcc catcttccat
     6721 tacaaatcta ccttcccaag gagtagatgt aaatttacca gtttcatcta ctggttgaat
     6781 aactggtaaa tcatatcttt tacctgtgtt gtagtcatct tcaccaaatg ctggtgctgt
     6841 atgaactata ccagttccat cttcagtagt tacataatct cctactgtaa taaaaaatgc
     6901 ttttttgtca acttctacaa aaggcattaa ttgttcatat tctaaacctt ctaggtcttt
     6961 acctttcatt tcttctaaaa cttcataatc ttcacctagt actttatcag ctaaaggttt
     7021 agatacataa tatacctcat cacctttttt aacttttaaa taatctacat cagcatttac
     7081 tgttaatgaa acatttgatg gtaaagtcca tggagttgtt gtccatgcta agaagtattc
     7141 atcagcatct tttttcttaa atttagctat aactgtatta gtttttactt ctttatatcc
     7201 ttgtgcaacc tcatgactag caagaccagt tccacatctt gggcaataag gaagtatttt
     7261 atgcccttca tatatatatc cttctttgtt gaatttgttt agtatccacc atacagactc
     7321 tatatagtta ttatctaaag ttatatatgg attatctaaa tcaacttcat aagccattct
     7381 ctcagtcatt attctccatt gtttttcaaa tgagaaaact gactctctac atttttggtt
     7441 aaattcagct attccatatt cttctatttg ttgcttacta gtaagtccta actctttctc
     7501 tacttgtatt tcaactggta atccatgtgt atcccaacca gcttttctct ttacttgata
     7561 accagacatt gttttatatc tacaaactga atctttaagc gttctagata aaacatggtg
     7621 tactccagga tttccattag ctgttggagg tccttcatag aatacgaaac ttgggtcatc
     7681 tttccctttt tctaaagttt tttcaagtat atttatgtct ttccaataat caaaaacttg
     7741 tgcttctgct tgttttacag aactgtctac caatggctta aatttcgcca tgtaaatcac
     7801 cctttcctac taaatattat aattccaaaa ttttttattc tttcacataa atttaaatac
     7861 taaaaaactc gcccccttta aaccaaaggg acgagttata aatcgcgtta ccaccctaat
     7921 tctatatgta aactaaatac tagctacata taacactcta atagtataac ggtactaacc
     7981 ggcacagctt agtagaattt aatcgttcag cctgcagctc aagagtgatt tttatcttta
     8041 taaattcatt ggttctcagc atacccaatt ctctgtaaaa ttatctaaag ataaatgtct
     8101 ctatcaacgc ttttaaaaat ttatctgtgt ttatatgaaa ttctataaca aataatttga
     8161 atagtcaata tatttttgaa aaatataata atttctattt ttcttacatt tttatcctat
     8221 ttttaatctt tgttatagat ttctcaaact cacacaatta ttctacataa aaaataaaca
     8281 aattacaagc ttattctaaa gttgtagcag cttcatcatt actataatta tacactgttg
     8341 ttccttcaaa tgcgtttaca catttttcat ctacatcata aaaaatctca tcaacacttc
     8401 ttatttcatc ttctaacagt gatttaaatt tatttctaaa tatcttaaat tctttgacta
     8461 aagcatcata ctcttttctt atctctataa cacggttatt agcttgttct ataatttgtc
     8521 tagcttttaa atcagcttct tcaacaatta tcttagcctt tttattagcc gcactacaag
     8581 tgtcttctgc tgcactttga gcagttatta aagtggcttt tagtgtttct tcaatatttt
     8641 catacttgtt tacttggtct tgatataacc ctaatttttc tttaagagct gtattttccc
     8701 tacatagaga ttcataatct tccttgatga tatctaaaaa ttcatcaacc tcttcatctc
     8761 tataccctct taaacctttt ttaaactctt tattttctat ctcaattgga gttagcatta
     8821 catttcctcc cagctataat ttaaattagt ccttatacaa ttaatcttgc ttgaactttt
     8881 atttttcctt ttttagtaat atctcctatt tgtgttacct tagctcttcc tttgcctcta
     8941 atagaaatca aatcatcatt ttttactatt ttagaagttg aagttatctt ttcataattg
     9001 acatggactt tttctccatt tatgtatttt gcactatctt gtctagatat attgtaaata
     9061 ccacttatca cacaatctaa cctatctgaa gatactgtaa atgatacttc tttatatttt
     9121 gaagaactat taacaatatt ttctctggaa atttccttta caattacatt atttcttgaa
     9181 accttttcta agtttacaat tataaaatcg caaatatcac tacttacaac tacttgacaa
     9241 aagctatcat gtataattat atctccaatt ttttctcttt ttatacctag acccagtatt
     9301 gaccctaagt aatctttatg agatatattt ttaaatttga aattcccttc tatttgtaaa
     9361 aatctaagag tatcttctat atcttcatat tccatgtaaa atggataaat aaatacagtg
     9421 cttctttcag ctcgttcata acctccatcc acactgtatt ttatttcatt tgtagaattt
     9481 aatattgcta cagcattttt cacttcatat ggattaagaa actccgtaga cttaacatca
     9541 tagtttttta tacaactatt agccttgtct atcactttaa acattttatt tttcaagtct
     9601 atatccttta tgtgatttgt tagttttaat ttatccatcc tatcacctta gaatataacc
     9661 aatactaatt gtcttaggaa catcaataat actattgcaa ttaaaggaga aaaatctata
     9721 ggtccatttg tatatttata cattatagac cttattggcc cttctattgg ctctgtaaga
     9781 ttttccaaaa tatcaaaaat tttactttgt cttccatttg gaaaccaagt catcaagctt
     9841 tttataacta tcatccatgc tattatatct aaaagataat aaagtgcaat tcttattgtt
     9901 cccatatatt aaccgccttt ttactattta ttttgccaag ggaagaatgc tttactttct
     9961 aattcttttt tcatatttgc atctatatcc acattattag gagctagtat aaatattgat
    10021 ttagaaacct tttgtatact tccatctaag acataaactg ccccattcat aaagttaaat
    10081 atagatttac gaacttcaga attagtcaat ccttccaaat tcactataac tgcccttctt
    10141 tgttttagat ggtctgctat agttgcagct tcatcataaa ccttaggttc aactattaca
    10201 actttcattt ggctagttgt atgtaaattt acaattttat ttgcttttgc agtactaaag
    10261 ccactgttca tttcttcttc ttgaactata tcgtccatgc cactttcata ttcatcttca
    10321 atgtaatctt cttcttcatc aactatccaa ttcttaaatt tagatattat tccatttgac
    10381 attattaact tcctccttaa aatttattca aatttgagta attatttttt attgtagttt
    10441 ctttctccaa agattgatgt tccaactcta acaatggtag ccccttcctc tatagcaatt
    10501 tcataatcgt gactcattcc cattgacaaa acatccatcc ctacattagg gatgtttagt
    10561 tcttttattt gttttgataa atctttaaga cctttaaata cacctcttat ctcatcttca
    10621 tcttctataa aaggtgccat tgtcattaga ccctttattt ttatattttt atatttttct
    10681 gacacttctt tgacaaagtc tacaacttct tctctatcaa gtccatgctt agactcttct
    10741 ttagatatat tcacttgtac taagcaatct atttctctgt ttatttgttc tgcacgtttt
    10801 tgaatttctt cgcataatgc aattctatct aaagagtgta tcatacaaac tttatcgatt
    10861 atgtacttaa ctttattggt ttgcaaagtt cctatcaggt gccagtttaa tttgtcacct
    10921 ataatatcat actttctagc taattcttgg ggtttatttt caccaacaga agtgattcct
    10981 tccctcattg cctcattaac taagtctaca tcaacagtct ttgtgactgc caaaagggta
    11041 atctctttgc tgtctctatc tacttttttt gcagctttat caattttgtt tcttatctca
    11101 gacaaattat ctttaataga acccattatt atcacctact ttatccttat atttgtgttt
    11161 atactgttag gtcttaaaat tattttgtca tatagattaa cacttgtaac tccatttatg
    11221 tcatttttat aataatccac aaatacagaa gattcattct cataagttat tccttctaat
    11281 atgacaaatt ttacactttg tgattgttca tcaattacat atacaccacg tttattgtct
    11341 tttgttttta tagaagtttt aggtattttt aaacattcca tctgattata tattatatca
    11401 aattcttcga cacttgtatc ctgatttgca acaatttggt tacttatttt taattttact
    11461 attattttat tattattttc atatattttg taaacttttg catctaattt ttgctcatga
    11521 tattcaatta ttacattttg atttttttca aagttattag aatcttcttt actgatgtat
    11581 gtagatagat aattactctg gtcattggca tctttttcta tacttccttt tacatgaatc
    11641 tttgcatcaa ctttttcatt ttttaacacc aacgtattta catttttgct aattatcatt
    11701 actaatatat taaatactaa atatataaga ataccaagta tcactaatct ggtatatttt
    11761 acctttttca aagactctcc ccctataaaa ttactttcat tataagtact tcttctaaaa
    11821 aatgtttatt ccttttttat aagctaatat tttacgttct aataattatt ttttccatat
    11881 taaatttatt ttttatcaat cttcctatac aagactgcat tatttatata taattgtatt
    11941 ataaagtata agtttaattt acattttata cgttaagctt actttatatg tttttatagt
    12001 tatttttatt tttagataca atataaaacc aattaagatt taaaataact tttgttatgt
    12061 tgacatttat ttaggtaatc atttacgaat caggataacg ttatcataac aaaagtttat
    12121 gtcctaaaaa aaatacaagg aggattttct tatgtcagaa attttattag gaacaggttt
    12181 acttttattg gttctatgtt gtttcacaat ttttagttac aaggccccat atggtatgaa
    12241 ggctatggga gctctagcaa acgctgcatg tgctactttc ttagtagagg cattcaacct
    12301 ttctttactt ggtgatgttt taggtatgga attttttaga agtgttggag ctgctaatgg
    12361 tagtcttggt ggagttgctg ctgctatact tgtgccttta gccttaggtg tatctccagt
    12421 ttatgcagtt ttaataggat tatcttgttt agatttttct atattatctg gattcgttgc
    12481 tggatacttt gtttctttct taattaagtt tatagagaaa aaagtgccac ctggagtgga
    12541 tttagtggtt gtaattcttc tatgtgcacc actatctcgt cttatagcat caaatgtaga
    12601 cccattagtt aatagtacac tactacaaat tggacaagtt ttgatagaag ctaccaacat
    12661 tagccctata ataatgggaa ttatactagg aggtctaata acagtagttg gaacgtctcc
    12721 acttagttca atggctctta catctataat tggtcttact ggtcttccta tggcaatagg
    12781 agcattaggt gcttttggtt cagcttttat gaactcaaca ctatttgcaa aattgaaatt
    12841 aggttctaaa aaagatatta tatctgttgc tattgaacca ttaacccaat cagacataat
    12901 ttcagctaat ccaataccta tatattctac taatttcttt ggaggagcct tttctggtat
    12961 cattgtagcc ttgatgggtc ttgtaaacat gacaccaggt acagctacac ctgtggctgg
    13021 ttttgctata atgtttgctt ataatccagt tcaacaagtt cttataacag ctggtttatg
    13081 tgctttattc aatgtaattg caggattttt aggttcaaaa atattcagta cctttaaagt
    13141 tcttactgct ggtgaaatac gtggtactga tgtagaagaa gaaattgctt aaaaaacaat
    13201 aagatttata aatttatatc tcaagtagta gagttttata ttgtaggcaa ttttattaat
    13261 tgcaaacgtt ttatttttta tttatgttta tgattattat gtgtgttgaa tatttagata
    13321 aatttttatt tattattttt atttagattt ttgtttagtt ttttatttgg ttgatatatt
    13381 aggaataaaa attagtatag tttattacta gttagatggc ataacttttt agatacataa
    13441 aaaattttat attaattaga tattattaaa ataaaagcga tacatgaatt tttaaatgtc
    13501 catgtatcgc tttatttttg ccataatctt aataactgat ttttaaagtt tattatctta
    13561 acaaagttca ttatcttata taatatttaa atgcataggc ttctttaatt taaccatcta
    13621 aatatttaat taaacattat tatatgtaat ataactaatt tttaaatgaa tgtataggag
    13681 ctggaatcct tcctcctctt tgagtaaata attcagatga atttgtattt ataggcatta
    13741 ctggtgctcg tcctaaaagt cctccaaatt ctaccatatc acctacatca catcctgggg
    13801 ctggtataat tctaacggct gtagtcttat tattaatcat acctattgct gcctcatcag
    13861 ctatcatggc tccaagcgta cctgctgtag tatttcctgg cacagctatc atatcaagac
    13921 ctacagaaca aatagcagtc attgcttcaa gcttatctat acttaaagca cctttaataa
    13981 cagcatcaat catacctgca tcttcagata ctggtataaa cgctccacta agtcctccaa
    14041 catgtgaaca tgccattact ccaccttttt taacagcatc atttaaaagt gctaatgctg
    14101 ctgtagtccc atgagtacca acaacttcaa gacccatttc ctctaatata tttgctaccg
    14161 aatcaccaat agcaggtgta ggagctagtg ataagtctat tatcccaaat ggaacatcca
    14221 atctactaga agcttccttt gccacaagtt gtccaactct tgtaatttta aatgcagtct
    14281 ttttaactgt ttctgaaaca acatcaaaag gctctccctt tactttctct aaagctctct
    14341 taacaacacc agggccactt acaccaacat ttataattct atcagcctca ccaacaccat
    14401 ggaaagctcc tgccataaat ggattatctt ctactgcatt acaaaatact actaattttg
    14461 cacaaccaaa accttttgca tcttttgtta attctgcagt ttcttttatg atttctccca
    14521 tttctttcac tgcatccata tttataccac atcttgtaga acctacattt actgaagcac
    14581 atactttatt agtacttgct agagcttttg gaattgactt aattagtatc ttatcacctt
    14641 ttgtatatcc cttttgaact aatgctgaga atccaccaat aaaatctata cctaaatcct
    14701 ctgcagcctt atccaatgtc tgtgcaaact ttacatagtc attttcatct gttgcacctg
    14761 caataatgga aattggagtt actgataccc ttttatttac aattgggata ccaaattcac
    14821 gctctatatc ttttccaacc ttcaccaaat ctttagcaga actcataatc ttattgtata
    14881 ttttttctct agctttatct ccatcagggt ctatacaatc taataaagaa atccccatag
    14941 ttatagttct tatatccaac tgttcttcat ctatcatctt tattgtttca agtatatttc
    15001 ctacattcac tattatcacc tccccttact gtctactaca gattatgcat tgaattaaat
    15061 atttcttctc gctgaatttt tacatccact gataatttct tacctctttc aaccaagtcc
    15121 tcaaccgttt tctcaaaaga atttaatgat ttctccaaat caactatcat aatcatagta
    15181 aaataatcct gtaatatttt ttgtgatata tctactatgt tgatattttg cttgtataat
    15241 tcatcactaa ttcctgccac tatacctggt ttatcctttc caattactgt taaaattgct
    15301 ttcataataa tatcctccct tattttttta taaatcttat atttttacaa attgaactat
    15361 gtgttaacat atatttcatt tatttgttag taaaccactt tttatgtata tatttaatat
    15421 attttaatac ctatacattc atttgtcaat tttttttcaa tattctatta tttttatact
    15481 atttagaaaa ttcatatatt atatatgttt tctcaacaat aaatacagtt ttcataataa
    15541 tgaaaggtat tacttagcaa tctcatgatt ttctaaataa tacctttcta aaaattattt
    15601 ttttaatttt atgaatttaa ttatactttt tctagtatca ggatttacaa ttaatataga
    15661 accaatcata attggtgtta gtatacaaaa taaaaaaata atatcttttt ttagattata
    15721 ttctttagat tctaatttat aattattatt tattattcca tcataatcac ttatatttga
    15781 cttattttta tttgtatctt gatttttgtt agaaatactt tccctataag gaaaagaatg
    15841 ttcattggta ccaaatactg attttgagct taaatcataa ttatcatcat tttctgtaat
    15901 tgaattttta ttgtaaaatc ctttttcttt atcagaatta ttttctttat taccgtcttt
    15961 aggtatatca tgaggatttt tattttcatt gctatcagta cttgattcta catcatcttt
    16021 aggagtattt ggttgtttct catcagaatt atcattttca ttattattat tttcattatt
    16081 attattttca ttattattgt tttgattgtt attactatca ttattttcat ttccattatt
    16141 cccatcttga ttgttatcat cctcatctct atccgggtcg tctctacctc ctcctccacg
    16201 gtcaccatca atatcatcat tttcccgttc atcatctggt gtctcttggt tgtctccgcc
    16261 tcccattata aatcctggtt taaaaactat atttgaatac ccttctttta atcctcctac
    16321 cacttttact ctaaaacaac gcaacttaaa atcttcaaaa aaaagtatcg cttgatctct
    16381 aatatcctcc tgttcttcag atatccaatt gattccatcg cttgaatatt caacaaaaac
    16441 cttacttgca ctatacggca tatcataaaa taaaacagct acatatccat tttttgtatt
    16501 ttgaaattcc agttccaaat tgtctattgg ttttttctct ataacagata cattcaaaat
    16561 aggaactaca tcatcattta ttataatttt ttctttattt aacatttctg ttttaaactt
    16621 tcccgttata ttaaaatctt ctcccttttc caacttttca taataatcag taaaatccca
    16681 ttctacatct atatcaagtc gattaccact agatgtttct aataccatat atttgggaaa
    16741 ttttatattt tctattttat catctttact tacttttatt tcatcactaa atacaccaat
    16801 tcccctatga caacatttca caatattata gccagaatct tcagctatag agggtataag
    16861 ctcattataa tcatcaatta tataaacttt cttactttct gatataattg attgtgccaa
    16921 cttattatta tctcttagta acccactttc attgttgcta ctatatgctt ttattgaagt
    16981 ttcttctatc tcaacatcac ctttagaata aacacctata gcatgttctc cattcacttc
    17041 aatatcctta tttagtattc taatatcatt ttcagtataa attcctattg catcttttcc
    17101 atttgccttt attttttcaa cagattcgta ggatgattta atatgtaagt ctcctccttc
    17161 ttcaacgtat aaggctgtcc catcagtagc aattatgttg tttataccaa tacttatact
    17221 tccaccattt tctatatgta ttactccttc ttttcctcct tcacctatta tattcaattc
    17281 attatcatca ataataaatc tcccatgatt ttttatcaat attttatatt tgttggtatc
    17341 tattgtaaaa ttactgtcat aaggaatata aaatctaaac tcttcatcta ttaccatatc
    17401 acaagaaaga gtataaacta tttcttcttt attattttta ttttcttgaa cccacctttc
    17461 aaaatcttca agacaatttt cctcttgtcc aaaaacttta tgtggaaaac ttataaaaca
    17521 caaaactatt atactcataa aaataaatat ctcatacttt ttcatcttac actcctagaa
    17581 atttttagct ttgaaacaat cctgtcgaaa catatacttc acccactata atttttccac
    17641 aattatcaat tattgtcaat ttatataagt atctttatta attgttataa ataaaaagct
    17701 acttactaaa gcaaacagac gtttcacttt aataagtagc tatattttta taacaaaata
    17761 gttataatat tagaacttcc ttcatttaca attttttgta aagtcttttg cattttaact
    17821 cttatctctt ctggcatagt atataattta ctttgtaatt gctcttttac taagtcatgt
    17881 agtgatttac caaacatatt tgattcccat aaatctgctg gttgctcttc aaatacttcc
    17941 ataagatatt ttatcatctc ttcaccttga ttttgatttc caactattgg agaaacctct
    18001 gtagatatat ctgcttttat aatatgaagt gatggtgcat tggcttttaa cttgatacca
    18061 tattgttttc cttgtttcat tatttctggt tcttccagac taagttcttc taaagaagga
    18121 gctactactc catatccttt tatcttggca tctattaaag cactttctat tttatcatac
    18181 tcatttttaa ctttagatag tctagttatc agactaagca gttgataatc tccttcaatt
    18241 ttaaatccac ttttttcttc aaggacatta tagaataaat cttgctttgt ctgtaaatca
    18301 atatttataa caccttctcc tagctctaca ttatcaacac ctgtatcttc caaaaactct
    18361 aactcagaaa atccttgtat aataccttct atatccctta ttttacctat atctataata
    18421 ctttgtttta atgttgttat tatgctactt tttatccaat gatttctttc aagaccttca
    18481 acccattttg gtaagttgat tcttatttct gtaagtggaa aatcatataa tacagcttcc
    18541 ataacctcct ctatatcttc ttcttccatt tcaaccacat tcattggaag aactggaact
    18601 tcatactttt cttccaattc acttctaagc atactcgttt cctcactttt tggacttaac
    18661 gtatttaaaa ccactgcaaa tggtttttta agatttttca attcttgtat aactctctct
    18721 tctggttcta catagctttt tctgtcaatt ccagtaactg aaccatctgt caagacaact
    18781 atccctattg tagaatggtc ttttataact tttttagttc ctatctctgc tgccttttca
    18841 aatgtcatag cttcttgtga ccaaggagtg gatactaatc tttgttttcc accttcctca
    18901 tgccctaaag ctccttcaac tatgtatcca acacaatcta ccattcttac ttttaaagat
    18961 actgtgtctt ttatttttat ttctacacca tctgctggta caaattttgg ttctactgtc
    19021 attatcgttt tacctgaacc actttggggt atctcatctc ttgttctatc ctttttaaat
    19081 tcattgtcta tattaggtat aaccaacttt tccataaatt ttcttataaa agttgatttt
    19141 cctgttctta caggtccaac tactccaata tatatatccc cctgagtcct tttggatata
    19201 tcttcgtata tgttattatt catattattc ctcctataca tctaatctta ttaaattata
    19261 tttagagtta agggttaata ttcttaaaat agaaaaataa agaccagcaa tattaattta
    19321 atttacatat agaaatttgt aaatttcaat gtaaattaaa ttaatattgc tggtccaaat
    19381 agtagtgtat tatattaact gactttagta gcattttcat ttgaattatt attcatctca
    19441 ataagttctt tacgtctttc ttttgtcatg ttcatccata taaatgtaaa caccaatcca
    19501 attatggcta ctatagtaag aactatgaag tagtacctat atccagttac acccggaaat
    19561 gcatccaata tcttccctgc tgctaaagga caaagtactt ctggaagata tcctaacgta
    19621 gcaactattc ctatagcagt tcctgatatt gataatgaat aattaccttc ttcaagtaac
    19681 gaatagtgta aaccttgaat tgcatacata gatacatata ttgcaacaca tccaatcaat
    19741 agtatataaa tcatagatga ttttgttggt gtaaatatta cacctaaaag acctgcaatc
    19801 ataagtataa atccataaga tataatcttt gatgaaccaa ctttatctcc aagtaatcca
    19861 gaagcaactg atgctactgg tctacaatac tgagctaata ttgagattgc agatgcaaac
    19921 accacagtag ctccaaatgc ttcagttgaa taaggcgtaa aataataaaa tgacatatta
    19981 gctgaatatg aacaaaacat tattattgtt attatccatg tatgaggcat ttttattact
    20041 gcaaaaaagg cttctttatc aaattttgct gatacctctt tttcattatc ctttaatttg
    20101 aaaaatacta atactccaac tattacattt attaccgagt ataatactat aatagctgta
    20161 agaccagatt tatcacttac ttttgatgaa atatacccaa atagtatcaa tactagagat
    20221 agatgaattg cattggtaat tccacgacca ctttccataa atccaaaagc ttttccttgt
    20281 tcattttcag atgctaacat tctaacagct tttacaagag ctggccaaaa agtaagtatt
    20341 gttgttattc cccataaggc atggattaaa aacacaacaa tatatggagg ataaagtgtt
    20401 aatacaagac cagatattcc tgtaataatt aaagaacctg aaagcaattt tctggctgaa
    20461 atacggtctg ctaaaaaacc accaaaaagg tatgatacca ttgcaagtag accataaatg
    20521 cttcctaagc ttcccatttg tgtatttgta agattaaatg cttgtgcaaa agtatcataa
    20581 taataattct ttaaatatgg taaagcatat ataaatgctc ctgctacaaa gagtattatc
    20641 aagactttga aatttttcca aatgcttggt ttatttactt caactgacat acttcctcct
    20701 tatgtaaata cctgtaaatt ttcatgataa ttaattattg cttattgtat tgtttattca
    20761 atatttcgga atatttatta atatattagg ttaatctatc aataatttat ggtgagttat
    20821 gagctaaaag taaactcttt tagctcacca taataattat atttttattt atactaacgt
    20881 ccagagttat tagatatctt tttttcatag ttcttccata gcattaaacc tgttattata
    20941 acaaaaagac ctcctcctat catttcaatc tcatagatta tattatcttt taaagtctcc
    21001 ataactggtg ccgttgagaa aagtatgcca actacagtta ctacaagtac cattctggca
    21061 atattgatac aaactgaatc actttttgca attgaatatg gtctttcttc atttggtctt
    21121 gtctttctaa gtctaatata agatgtaaaa agcaagacat atggaaataa tgctgttaat
    21181 gctgtcatag taacaagaac attatatata ttatctactg atggtaataa gtttgttcct
    21241 acaagaagta gactcactat tatagcctga actattactg catttgatgg tatattgtat
    21301 ttatttgtaa cagtcaattg cttaggaaat acaccttctc ttacatttcc aaaaagcatc
    21361 tttactggac ctgctatata aagtattaat gctcctagta ctgataaagt tattccaaat
    21421 gctactattc ttataaacca acttcctata cctaaatctt gtgcaacttt agctaatgca
    21481 tctagtatcc ctgtagatgc tgcaatttta tctggaggaa gtatcattgt tattgctact
    21541 gaacctaaga tatagattcc tcctattaaa acagccacag ttaatatagc tttaggaaag
    21601 tttttcttag cattatccat ttcggttatg aaattagcag tcgtttcagc tcctgataat
    21661 gcaaatatta tagcagatat agaaactaat gaattggcat ctatttttgg tattatattt
    21721 tggattgtat atatcgatgc tgatggagct tttttgagaa taactacaga cataaatgcc
    21781 atcactataa gtaatatagc aggaattgta gaacctaatg ctcctgtatt cgtaaaaaat
    21841 tttccaaatg ccatcccacg agtacttact aaggacaaca gccaaaatat tatgagtgaa
    21901 agtgctaaaa taaacatctt attgtttgat aaatctggat ttccaagcat atatgcaata
    21961 tttatagcta aaaatgttaa gaaagaagaa taccaaaata tctttgatgt ccaatttagc
    22021 catgacacca taaatcccca cttctctcca taagcttgtt taacccattc tccaagtcca
    22081 ccatcttttg gatatgttgc agccaactct gcacatataa gtgatgcagg aacaaagaat
    22141 ataaaagcaa acaataacca aactggtata gaaccaagac ccaatccaaa actagaggca
    22201 gtagatttag ctatccatct aatcccaaat agtgctgata tattcataaa tactaaatcc
    22261 caaaatccaa ttttcttttt cactgtaatt cctccaattt caaatttatt caaactcata
    22321 cactatgtat tgatttaaat atcaagtata agttcttcaa cacttcttgg ataattagtt
    22381 ataattgtag caccattctt acctactatt gctgtatctg agtgtctaaa tcctccaact
    22441 ccaggtatat atatccctgg ttccatagaa aataccattc cttcttctaa tattaattca
    22501 ttgtcaaatc ttaaatatgg ctcttcatgt tctgataaac ctaaaccatg accaattcta
    22561 tgatttgaat ataactctag accatacttt gcaacaacag ctcttgctgc ttcatccacc
    22621 attcttgctg gtataccagc ttttattgta tctaatccag cttgttgagc ctctactgca
    22681 atcttaaaca cttctttttg tctttctgtt ggtttgccta taataaaagt tctttcattt
    22741 tctgctctat agttttcata ccaaacctgt ctactatgta ttactatatc tcctctttga
    22801 agtattctag tattagaatc taaatgaggt tgtgctgttc tatcaatccc tgaacaagtc
    22861 cagtttgcaa atcctatata tgtatcagga taattttcag aaacatattt tagtaaagca
    22921 ttatcccctg caacgtcaaa ctccaattca ctcatcccaa ctctaacatt ttctaaagac
    22981 ccttttattc ctatatcaga taggtaacct gctatcttca aaaattctat ttcttttgca
    23041 tcttttacat atctcatttc aaatatttta cttccaacat ctttgatagc aaatgactta
    23101 tcagttatat actctgaaaa gcttgcagat actatatctt tttctattcc aacagttgtt
    23161 cctttagggt atttatttaa aattatatct aagtaatgtt tatgtgatat tccatgttct
    23221 ttcatttctg gtatttcata atacacatat acattatcaa cttttgcaac ttctttagca
    23281 tgtaattctt ctaatccagg tactattaat tctattttat cttgagttac tactgttaca
    23341 attggtctag aataagttat tgctttaaat ccactaatat aaaattgatt gtctggttca
    23401 aatattaaag caatttcaat gcttttttca ttcatgtact ttctcaatct ttctagtctc
    23461 atattatttg acataatgca cctctttctt aatattcaga taatttattc aatacaacaa
    23521 ggatgaatat attattttaa aattcttaat atttttagta cttgtcgtat ttgtatgtaa
    23581 attaatttta tttgtgatta ttttatcata atcatgatta ttttgtcaat catgatttta
    23641 ttttaaaaaa ttttttatat tctagtgatt ttaaattatc taaaatataa cgagtataca
    23701 ttgtattttg taatattatt cttgatttat ggtaagttta atgataaaat cacgattata
    23761 taaactatat tgattatttg taggtgaata aaatgacaaa taaagaatta caaaagaaaa
    23821 ggatattgat gtatttcata gaagctgctc aaaatattat ggaaaacgaa ggtatagaaa
    23881 atattacact tcgtaaggtt gcagatatgg ctggctataa tagttcaact ctatataaat
    23941 actttaaaaa tttagaccat ttaatatcat ttgcatctat aaaatatttt aaagattata
    24001 acttgaatat ttcaagatgt atagaaaatg tcaatgatga atataagaaa tatataatta
    24061 tgtggaaatt attttgtaag cattcttttg ataatgctca agctttttac caggtatttt
    24121 ttaacttgtc tagtgatgaa cttagctata taacaaaaca atattatgat atgtttccag
    24181 aagatttagg tattcatgat agtgacatat ctttaatgat tacaggagaa agtataaagg
    24241 aaagaaataa gatactatta aacaaccttg tagatactgg atatatacca gctaaagatt
    24301 tagacataat caatgatata attatttctt tttatcaaaa tctattattc ttaaaaaaga
    24361 acacaggaaa aaattctgat gatgatgaat taactatgaa aatgatttct tctattgaat
    24421 acataataaa acatgctgaa taaaattaaa atatggctgt ctcaaaatag agataagcct
    24481 tttttattgt tgaaataata aaaatatatt taatttcata taaaaaagag tgcctcgtaa
    24541 actaaaaagt tcattttgag acacccctaa aataaattta ttatttatta tacaatagtt
    24601 tatatatcat cacctaaaac tacttcttcc atttcatgct ttttacttct catcattagt
    24661 tctattccaa cttctttagg atttgaacct ttctttatta cagaatatat agcattagtt
    24721 ataggcatat ctatatctaa tttttcagca acatcatgtg ctacttcagt agcagttatg
    24781 ccttctacaa ccatctttac ttcttttaaa gtatcttcta aactcatacc tttacctatg
    24841 agtataccag ctcttctatt tctactatgc atacttgtac aagtaactat taaatctcca
    24901 atacctgaaa gacctgcaaa ggtagacata ttagctccca tagcaattcc aagtctgctc
    24961 atttcactaa tacctcttgt cataagggca gcttttgcat tatcaccata ccctaatccg
    25021 tcacatatcc cagctccaaa tgctataata ttttttaatg ctcctccaag ttctactcca
    25081 actatgtctg gattcgtata aactctaagt ttagggctca taaataaatc ttgtatcatc
    25141 tgtgctattt ttaaatcttt agaagcaact actacggtag taggaatatc ccttgctact
    25201 tcttcagcat gagatggccc agatagtatt acatatggat tttgtggtaa ttcttcttca
    25261 cagacttgag ataatctaag cccagtccct ttttcaagac ctttagctac attaacaata
    25321 acttgtcctt cttttataaa tggttttatt ttttggcaag tacttcttac agcctgtgat
    25381 ggaactgcta aaactatcac cttacaatct tttatagttt tttctatatc agtacttata
    25441 attatattat ttggaaataa tactcctggt aaatagtctg tattttcttt agttctgttt
    25501 atttttttag cttgttcctc ttttcgagtc cacatgctca catcattacc tttttttgca
    25561 agccctaaag ctaatgcact tccccagctt ccagtaccta atacacatac tttctccatg
    25621 tttaacacca cctgagtata atatatttac tattctttct tttgaccaat ttttctctct
    25681 gtcccattta ataatcgctt tatatttgct ctgtgattat atattactga tgcagttaag
    25741 aacagagcta ctattaaacc agctttattt tttaccataa tcataaatat tggtgaacat
    25801 cctattccta caacagaacc caatgaaaca tactttgtta tagctaccac caatataaat
    25861 actgctagac acattagtgt tattactgga tttacagcta gcattgcccc tagtgaagtt
    25921 gcaacacctt tgcctcctct aaatcctaaa actgctggcc aattatgacc tgctacaaca
    25981 catataactg ccagatatcc agctaaaaga gtatctattc caaccaatct tgctgcaaat
    26041 tctgatatta aaacagccat tacaccttta agaacatcac ctaaaaatgt cattgctcct
    26101 gctctttttc caagtgtcct aagtacattt gtcgaacctg cattaccaga accttgagtc
    26161 cttatatcaa ccccagcaat tcgctttgca actatgtatg aggtagatat atttcctaaa
    26221 agatatgcaa ctacagcaat aattatataa ctaaatatct ccactgaatt tccccccttt
    26281 agttatattt taagatattt attttttatt tttttgtcta tactcaaact ttatggaagt
    26341 tccttcaaat ccaaaatttt ctcttatctt attctcaagg tatctttgat atgagaagtg
    26401 agttaaatcc ttatcattta taaacaatgt aattttagga ggtctaatgt cagtttgagt
    26461 cccatagtaa atttttaatc ttctaccttt gtcagatggt ggttgattta acattacagc
    26521 ttctccaatt acttcattca gtgctgaagt tgatattctc ttagaatgtt catttgacac
    26581 atattcaact gtatctagta tcttgttcat tctttgatta gtttttgcag aaacaaatac
    26641 gattggagca tacatcataa atggaaattt ttcttttata tcttttgtgt aattactcat
    26701 agtcttatta tctttctcta ttaaatccca tttattgatt acaaatatgc atccttttcc
    26761 ttcatcatgt gctatacctg caacctttgt atcttgttct gttacacctt ctaaggcatc
    26821 tattactatc aatactacat ctgctctatc tacagcactc atagctctta ttacactgta
    26881 tttttctatt gtctcatata ttttactttt tcttctaagc cctgctgtat ctattagaag
    26941 aaatttctgt ccattttttt caaaataagt atcaattgcg tctctagtag ttcctgcaat
    27001 tggacttaca attactcttt cttctccaag tatcttattg agtatagaac tttttcctgc
    27061 atttggttta cctgttatag ctactcttat tatatcttct tcatactctg tatctaatcc
    27121 tgctggaaaa ttttcaacta tctcatctaa taaatctcca aatcccatac tattggctcc
    27181 tgaaactgca aaaggcgttc caaatcccaa ctcataaaaa tcgtatatat tatcaaattg
    27241 actttgacta tcaatcttat taaccactaa gattactggt ttttttgtct ttctaagcaa
    27301 ttgtgcaatt tctttatcag cagctgttat tccagcttta ccatcaacta taaaaagtat
    27361 tacatgtgac atgtccattg caagcatggc ttgatttctc atttgagata atattatatc
    27421 ttcgctatca ggttcaattc ctcctgtatc cactaatgta aaatatttat ctaaccattc
    27481 tacttcagca aatattctat ctcttgtaac tccaggtgta ttttcaacta ttgatatcct
    27541 ttttcctgca aatttattaa atattgtaga cttaccaacg tttggtctcc caactacagc
    27601 tacaactggc ctacttatac tcattttatt tctccttcca tcttttgttt tctattttaa
    27661 aattttatcc acaaaatctt ttccttcatt caaacaaggg ataattttta ttctcataag
    27721 ttcttctaat tgatttaatt caatattatc taagaaaatt tcttcatctg cttttagcat
    27781 acttcttgtt atataaaggg cttcacctaa ttctttatct tcaagttgtt cttttaaatc
    27841 cttagctgtt aaaagacctg atacagttat tgtctctcca aaaaacttgt ttttgatttc
    27901 atatacattt acttgaagat ttttaaactt gtccatcata gcatctgcca tactctgtat
    27961 aaattcatat gcagaatgac cagtagctat tgatactttc ttctctcttt ttagaatatt
    28021 ctcaggcaat atatttagat actcttcaat ctctgttttt aacttacgta tcatacctac
    28081 accatcttca aactgtaaaa aaccttcata ttcttcatat ccaggcaatt cactattaga
    28141 tagtatataa aattcatctg ataaaaatgc aaatcgagta cctaattttt caagatattt
    28201 ctgttgtatt tgatgtattt gctctatagt tttacttgcg ctcttatcat taaatatatt
    28261 taattctact agattttctc tatgctttgt aatcccaact ggaactatcg caacactgtt
    28321 tacatatgga taaagttgag ctagttcttt tattgttcta tccaattcct ttccatcatt
    28381 tatacctgga cataaaacaa tttgacagtt catttctata tgagcatctg ccaatctctt
    28441 cattatacca tataattttc ctgcaaattt attgcttatc attttttgtc ttaactctgg
    28501 attagttgta tgcacagata tatttatagg acttattcta tattttataa tattatttat
    28561 atcttcttca ctcatatttg taagtgtgac aaaatttcct tgtaaaaaag ataatctcga
    28621 atcatcatct ttaaaataaa gagtttctct cataccttct ggcaattggt ctataaaaca
    28681 aaacatacac ttatttctac agcttttagc ttggtcaatt atcggatttg taaattcaac
    28741 acccaaatct tcatcatagt ctttttctat ctcgtatatg tagacttcgc catctttttt
    28801 ttgtatttct acatctaaat attcatcact tagtaagaat ctatactcta ttatatcatg
    28861 tattggctgt tcattcacag atataagtaa atctcctacc tctataccca tttcttctgc
    28921 aatactatct ttataaacct tacttataat attatttact ttttttacat ttacttccaa
    28981 tattttcacc actcttttgt attcatcaat gcttattata atgtatttta atatgaaatt
    29041 tatttattta ttatatttta tgatagcatt tttaagcatt tcatgtcata ataacacatt
    29101 ttaattctaa tagtcaatat aagtaaatag ctataaaata gattagaaca aataatattc
    29161 aaatttaagt ttcttaaaaa tttaaatatt atttgttctt aaaaaaattt tataaattta
    29221 atgttttact atgattaacg tcccatttgt catatcatga accattccac ctacacactt
    29281 tgacatcaac aatgccttat tttgtaagtc tttctcatca tttgcataaa atattggaca
    29341 acctccacca tttttcatat tcttatcaag tgtaactata gctagggtat attcatttaa
    29401 acctatatcc attcccatct tatgcacttc ctttctttcc tattttataa ttttttagtg
    29461 ataagttttt tcctttagag cttgaaagta ttgggcatga ctttacagct tccattactt
    29521 tttccacatt cttatctact ggtaaataag caatcattat actttcatcc tctttatttc
    29581 ttctaggtaa tggtacgaat gaaggttctc cataatctcc atataaacct aaccttgaat
    29641 atatattgta tactattgct tgtctttgac cggagtcaaa taatattcct gcattagcat
    29701 aatccttatt tttaggaatt atttgtattc ctacacctct attaatatat acttctctat
    29761 cgctttttag acctatattt gttatacctt ttaaatctcc cacctttagt atagattcgt
    29821 ccacaaaact aatttcagca ggcattacat cagctatgtc tccaatactt tttctagtaa
    29881 gaagtttttt taatataaag gctaacacta atccacaaat tgaacttatt accaaactca
    29941 tcccttcact tattttcgtt tctgcaagta ttacataata caatcctatt gttaaaaaag
    30001 atgtaactat acacatataa tttcttactt cataggttct agctatctct tctatgaatg
    30061 cagctcctct ctttacaagt tgaacttcct ctaagttttg caatgtattt cttctatttg
    30121 ctctcacttg tctaaattgt tctgctgcta gagataaaaa tgttatggat gtataagaac
    30181 gatttataag agctggaacc aataatgctc ctaatgaaga agcgacgaat gctaatataa
    30241 gttgagatag taaaacattt ggttgcgttg gatactgttt ttggtctaaa ttcaacatta
    30301 taattctaga tgttatacca ataataacag caacaaaaaa tactctatcc attaaatcac
    30361 tcctaaaata tttaatttga aattttacat gtaaatctac aaagtctttc tagaaaaatc
    30421 actctgcttt ccttttgatg tttctatgat aggtgtactt ttcactacat ctatcatgac
    30481 atctatatct ttgagtattg gcatatatgg tataaccaca gtactttttt ctaaattggt
    30541 cttagatata gcaacaatat caacctcatc tacatctcta tctatcccca tatgaataaa
    30601 tagattatgt attatagctt gtctttgccc tatatcattt actattccaa atgcacctaa
    30661 atctcttggt ataacttcta tagccagaca ttcatttcta tacttttctc ttgtactttc
    30721 tagacctatg ttagttatta ttacaccatt taccattaaa ataggtcctt caaaacttat
    30781 ttttgcagga actatatctg ctatatctgc tatactgttc cttcttaaaa atcttctaaa
    30841 aatcaaacca acaatagctc ctgacacaat agctaagatt gtgcaataaa aaaagctaag
    30901 gccatacttt cttgcaaaaa cgatataaac tatcgaagat accagtgcag aaaaaagact
    30961 tatataactt ctagattcat acgtagatgc tatttcttca acgtaagcgt ctccttttgg
    31021 tactaattct tcattatcga tattctttag tgttattctt tcttgttctg caagaccttg
    31081 aaactgttgt attgctactg caaaaaatgt caaggctgca aactccttat ctataagtgc
    31141 aggtaatgct atagcaccta acgaagctga aagcccagat ataattatct gttctaaata
    31201 atcttgtggt cttgatgggt attgtttgtc tgtaactctt aaaactaatc ctctacataa
    31261 tattcctaca actaatgcaa ctataaaaga gtgtctaaat aaatttgcat tcaataaact
    31321 ttcttccatt ttctcagctc cttctcttat atagtttgtg caaaaaacaa aaaaaattcc
    31381 cttctattta aggaaatttt tttgtaatat tgtaactata aattcgctac caatgccaag
    31441 ttcacttttt acttttatac atccatttag tgatttgact atatgctttg ttatagccaa
    31501 tcctaaaccc gttcctccta catccctact tcttgcttta tctaccctat aaaatcgttc
    31561 aaatatgcgt tctacatctt cttttggtat ccctacacca ttgtctataa ctttaattac
    31621 gattttttct tcatctttta atactacaac ttgtacaatc ccattatctt gggtatactt
    31681 tatagcatta tcaactaggt ttaagaacac ttgctttata tagtctttat tggatagtat
    31741 acttattgat ttatcatcac atttatataa aacttctata tttttttcac tagctgaatg
    31801 ttgagttatt tcatatacct ctttaaatac atcatatact acaacatttt ccataagaag
    31861 agtatcttta ttttctacaa atgataacaa caatatatca tcaatcaacc tttttaatct
    31921 atctgattcg ctttctatta tttctaagaa tctatttcta gtattcacat ctatattttc
    31981 atttgacttt agtgtttcaa caaacccact tatagatgta agtggtgttt taagttcatg
    32041 acttacattt gcaacaaaat cacttctcat attttcaagt ttaacttttt tagtaatatc
    32101 ttctatattt actatcgaac ctattattac gttgttagta ttctgaagat aaactgggtc
    32161 tacttttatc ttatatacga tatcatcttt agtagtaata ttagcagttt cattatcttt
    32221 agaaccaata aattgaagta tttgttttaa tatttcttct tcttttatta caacattaat
    32281 attatgacct tcaactaatt gatttggttc actctttatc atttcttttg cttcatcatt
    32341 tatcagaagt atatttccat ttacatctat agctaaaatt ccatgagata tactctttaa
    32401 tatagacctt aactgtaaat gtttatactg tacttcttct aaggttttat ccatattctt
    32461 tatcatatga ttaaaatttc tagctaattc gccaagttct cctttggctg atatgttaag
    32521 cctagcatga tattcattat tacttacttt ttttgagacg tatataaact cttttaaata
    32581 tttccttaat gttattgtgt atcttacagc taatataaca atggctatgg acaacataac
    32641 aataaaaaaa tatatactat ttaaatcttc cacaagataa cactcctaaa atataacctt
    32701 tttaatctat tttgtatcct acacctctta tagtctctat atatttttcc gatttatctt
    32761 catcttctat tttttttctt aaatatctta tatgaacatc tactgttcta gtttctccat
    32821 agtattcata cccccatatc ttatccaaaa gataatttct tgaaagtact tttcctttat
    32881 tttgaattaa taattttaac aattcaaatt ccttaagagt taactctatc ttttcagagc
    32941 ctttggtaac ttcatgtttt gataaatcta gttttaaatt acctgtagta agtatattgt
    33001 tttcttcacc taagctagtc aaattatatc tccttaaaac agaactaatc ctagctaaca
    33061 actcttttat actaaatggc ttagttatat agtcatcagc acctatttca agcccttcaa
    33121 ccttgtcatt ttccatattt ttagcagtaa gcattataac aggaatattt tttaagtcct
    33181 tatcacttct tatttttctc aaaacttcta ttccacttat atttggtaac atccaatcta
    33241 aaagtattaa atctggttta atttccttag cctttataaa tccgtcaaat ccatcatatg
    33301 aataactaac ttcgtaattt gacacctcca aattgaattt taatagctca actatatgca
    33361 tttcatcgtc tataacaagc actttagtat tcattaaaaa gctcctctct attttatctg
    33421 tagtaccgtt cctattcgtt ctgatgcctt attatgtttt ctataagagt ggaatttatc
    33481 tgctctacaa ctagtgcata aatttaaatt tattatattt tcttttttaa ctccactaca
    33541 tctaagcata tactcattaa ttttccataa atctaaatag taacttccct cttttattat
    33601 atagaacttt tcatcattat ttgtaagaat tgtgttaaat ttttctacta aatcttcaga
    33661 cacttcataa caacatggtc caattgatgg cccaattata catactaaat cttcaggaac
    33721 tgttttatag cattcagaca ttaattttat tgttttatga cctatattac taaaagtccc
    33781 tctccaacct gcatgagcca gtcctatggc tttattttta gcatctataa ttgatatagg
    33841 tacacagtcc gctgtaaaca gtaaaagtgg tactttttcc aagtttgtta taagtgcatc
    33901 tccatctctt cttttcccta tagtatcttt attgactata ttaactatat ctgaatgtat
    33961 ttgagaatta ctagttagat tttcaaatgt caaatcacat tctttacata cttttaacat
    34021 atcttctcta ttttttgcat ctatattctt acatgttata actagattta cagaatttaa
    34081 tttttcatca agttcttcac aattaccact taaattaaca tactctttaa tatcttgtac
    34141 attttttata tttatataat ctttcatcat ttgtctcctt tttctatcag tatactttta
    34201 agttcattta caaaagtatt tatatcttta aattgtctat acacagaagc aaatcttaca
    34261 taggcaacct catctaactc tttcaattta tccattacca tctcaccgat ttttttggtt
    34321 tcaatttctt ctataaaaca tttatttatt tcattttcaa tatgtacaac aatactttca
    34381 atctcgtcaa tagaaacagg tcttttttca catgctttta gcaatccata ttttatcttt
    34441 tctctatcaa aatattctct actattatcc tttttaatga ccattaaagg agttgtttct
    34501 attttctcat acgtagtaaa cctcttttta catgattcac actcacgtct tcttctgata
    34561 gattttaaat ctgtatgtct agaatctatt acctttgatt ctttataatt acaataagga
    34621 cattgcatct atattcctcc tttgtttaac tatatctcaa actcatctaa gcttaattct
    34681 gaacctatat ttactattat tgtatcacaa cctattttaa gtatatcatt ccaaaatata
    34741 acttcttcat cccctcctct tgaaaaaaaa cttctacttc catctccaaa aatggtaaat
    34801 gagactacct taccttcgtg aatatccatg tctatgtcta ttataaaccc catccttttt
    34861 ccatttttta catttataat ttctttttcc attatatcag aaactctaat catattgtac
    34921 tcaccctttc tttaaaaata aatatgtatc gaagtaaaaa aaaatgacct atataggtca
    34981 tttaaattaa aataatgttt acagtccatg gattacttat acatattttc tcatattttt
    35041 taaagcattt ttttcaattc ttgatacttg tgcttgagat ataccgattt catcagcaac
    35101 ttctatctga gttcttcctt tgtaaaacct taaatctaat accaattttt ctctactatt
    35161 taatttctta atagcttctt taagtgatat ttcttgcaac caattttcat cagtatcttt
    35221 tttatcttga acctgatcca taacgaatat tgcatctcca ttgtcttgat atactgggtc
    35281 aaacagagat attgggtctt gtatggcatc aagtgccatt acaactgatt ctacttctaa
    35341 ttctaattcc tttgctattt ctgatactgt aggttcttta gaatttgttc taattaatct
    35401 ttctctaact tgtagtgcct tatatgctat atcttttaat gacctactta ctctaattgg
    35461 gttattgtct cttagatatc ttctaatttc tcctataatc ataggaacag cataagttga
    35521 aaaccttaca ttttggctta aatcaaaatt atctatagct tttataagac caatacaacc
    35581 tatttgaaat aaatcgtcta tattttctcc tctgttgtta aactttttta ttacactcaa
    35641 gactaatctt aaattccctc ttacaaactg ttgtctggct tcttcatcac cattttttat
    35701 ttgtaataaa agttccttca tttgcttatt tttaagaact ggaagttctg atgtattaac
    35761 accacatatt tcaaccttat taacttgcat atattttcag tcctctctca aaagtattca
    35821 tctattgaaa ttatttacat ttccaatttt tttatacttt ttaagaagaa ttaatttagc
    35881 attatacaaa ttttttcatt tctttttgca accttgagat tattttcttt tcaagtctag
    35941 atatgtagga ctgtgatatt ccaagcattc cagcaacttc tttttgtgtt ttttcaatac
    36001 ctttatcaat aagaccaaat cttaattcca taatttgctt ttctctgtca cttaatctgt
    36061 caagtgccat aaccaacaaa tctctatcta tttcttcttc aattattttg tatatttcat
    36121 cattttctgt acccaataca tcagataata aaagttcatt tccatctaaa tctatattta
    36181 aaggttcatc aaatgatact tctgttttct ttttattatt ttttcttaag tacattaata
    36241 tttcattttc tatacatctc gaagcataag ttgccaattt tatattttta ttcagtttaa
    36301 aagtattaac tgcttttatc aaacctatag ttcctattga aatcaaatct tctacatcta
    36361 tacctgtatt ttcaaatttt ctcgatatgt agactactaa tctaagattt ctttctatta
    36421 aaattgactt tacactttca tctgtttcta gcttttgtaa aagctccatt tcttcttctg
    36481 gtttcaatgg aggaggaagt atatttgccc ctcccatata gtatattccc tttggcttta
    36541 ttatttttaa tttaatacct aacatagtaa taaagcttat tattctttct ttcaatcgta
    36601 acattccttg tcccccttaa attttcacct aaaatccagg caatatattt ggattcatta
    36661 ttgctccata ttctctatca ttaaaatttg aaataccaag tattatattt cctatctttt
    36721 gctcatctac ttctatatag tcagctttta agcctattat tatgcttgtc ttattacttc
    36781 cagcatgttt ataaggtatt attctaactc tacctgaagt tttatcatct aaacttccta
    36841 taatttcttg tgctttcttc atatctatat cttcataatt aatatttaat agtttttctg
    36901 gaataaatcc ttctaacaca ctagacttaa ctattattac atcactttga cttattgggt
    36961 cttttaacaa attaccacta tctactaaag ctttacagca aaaacttttt tctagtaagt
    37021 ttatatttat agtctttgta agctccttaa tgtacttaag cattttcaaa tctttataaa
    37081 tgtattttaa taattcacaa ctcacataag tacatgcaat taagaaagat atttttaagt
    37141 gacttattcc tgtaaaataa attataaaat aagtgcttcc agaaataaaa atgtttacta
    37201 gataaaaaac taacgctaca tgaacataat cttttttgct cttacttcta aatgaaatta
    37261 aagttattat actcatgatt attattttaa atggtacagt aaatagtata ttcattgatg
    37321 gatacaaata agcaacagaa taggcacctc ctaaactagc ccccaataac ttattttttt
    37381 taggattata tcttttagta agaatagaag tacaacttat aataatataa tttattacta
    37441 ggttttctat aacatagtac tcaatataca ccatgtatcc ccccttaaaa cctttaaaca
    37501 tattataaga tagtatgtac aaaattttat gtcacttttg atggtcgaat ccaaaacaaa
    37561 ttctatttaa aaagaacaat gatatatgtc ttatacttta tgtcgtcaaa agatattttt
    37621 ttaataccaa acaaatagac ttttttgtag aatccaatat atctaggtag aagttattcg
    37681 ctctactttt ggtatattta caaaaaaaag actacataat ttaataatat atcaagtaaa
    37741 tcttttactt atataaaatc aaattatata gtctgtaaat tcaaatataa attattgtgc
    37801 tagtaatcca tttgcatatt ttgcagattc atttagtgct tgttctggag ttatgtctcc
    37861 agctatcatc atttgaagtt gtttccataa atattcatat atctctactc catgaggtcc
    37921 aactgtcaat ggtctataca tatgtttatc tcttgtcacc atttcttcaa atcttgggtc
    37981 tccttggtat ttttcacctt tagcaactgg agctctaggt atttctttgt ggaaagcttc
    38041 cattgattct ttgcttagca tatactcaag aagtttaaat ccaagttctt tatttttaca
    38101 tgctgacatt aatgttaaat catctactga agcaaaactt ccaactgtct tatcttctaa
    38161 tgatgttaca tatccccagt ttaaatccgg gaatgattta tcaaatgtac ttgtagcagc
    38221 agaggatagc attatagtaa atgcagcttt tcctggtcca aatacacttt caatcatttc
    38281 attactatct tttgataaag catcttctgg aatatacttt ttcatatcat ttataaagtt
    38341 tgcagctttc aagccttctg cattattaaa tttaactgat tttaaatcat cattatatat
    38401 atctccacca gcttgccata aatacggata ccagttccag tttaagcttc caaatacttt
    38461 agaaccccaa ccttgtgcaa gaccccactg gtcgattttt ccatctccat cagtatcttt
    38521 tgttgctttt tcacagattc ttttaaaatc atcccatgtt tttggaggtt tttctcctaa
    38581 tttttctagt atatctttat tgtagtacaa tacgcctgga ttagcagctt ctataggtaa
    38641 accataaata ccacccatca tttttgcatc atctaagtat agataattat ctgaagttcc
    38701 tgatttttct aaataaggtg ttaaatcttc taccgcaccc atttctataa attgaggaaa
    38761 catctctgca tacatgtatc ctatatctgg accttcacct gcacttattg ctgttgcata
    38821 tttttctgcg tagttatccc atggtactat ctgaaattca atttcacagt tattttcttt
    38881 ttcaaatttt tcaaatatcg gcttccatgc atctgcatca tggtctgtta atggtgcaga
    38941 ccatacaact aatttttctt taccctcttt gcctttagaa tcttcttttt ttgaacatcc
    39001 tgcaagaatt gatactgata gaatccctac cataactaaa gaaagaacct tttttagttt
    39061 aatcatgctt aatccccttt cagactttaa tttgtctttt tcctcaaatg tttacattta
    39121 attcagattt aatattaaca aataagatta ctcttgtcta atcataaaaa actatactaa
    39181 ctcctataac tatatttttt ttctatacct attagattta attcatacta aaaacttact
    39241 ttttaaattt tatcaatatt taaaaatttt tttaagtcta gccacaaact aactatctaa
    39301 attgagcaaa ataaaaagaa gtctattgac ttctttataa gcttacatat tatcttcttc
    39361 ttcttaggaa tgtaggtatc tccatgctct catcatcatc ttcttcaatt atacttgcct
    39421 ttttaggagg ctctattttt tcctcagcaa ttacttcttc ttcaatttct tttacagctt
    39481 gttttactgt tgtatttaat gaagaacgta tgcttgattt aggtttagta tctaaatcta
    39541 aggcaccatt ttgtaatcct tcaaatcctg tcgcgattac tgtaatcatt atttcatcac
    39601 ctaaatcttc ttttatagaa gctccaaata taacatttgc ttctgggtca caggattcca
    39661 taactaaagt tgatgcctca ttaacttcaa ataatcctaa gttaggacca cctgtaacat
    39721 taagaagtac tcctttagct ccttgtattg atgtttctag aagtggagat tgaatagctt
    39781 gtcttgcagc atcaattgct ctagtttcac cactagcact acctataccc atatgagcaa
    39841 gtcccttgtc tttcattata gtagtaacat ctgcaaagtc caagtttatt aacccttcaa
    39901 ctgctataag gtctgaaatt gattgtatac cttgttttaa tacatcatct gcaactgcaa
    39961 aagcatctaa cattgatgta tttttttgta ctatctgtaa aagtctatca tttggtatcg
    40021 ttataagagt atctactttt gatttaagtt ctgctattcc accttcagcg ttcttcattc
    40081 ttatcttacc ttcaaatgca aaaggtttgg taactacacc tactgtaagt atccccattt
    40141 cttttgccaa gcctgcaacc actggagcag ctcctgtacc agtaccaccg cccattccgg
    40201 ctgttacaaa gaccatatca gctccttgaa gtaactttac tatttcatct ttactctcct
    40261 cagcagctct tttccctact tctggatttg ctcctgctcc aagtcctcta gttaattttt
    40321 ctcctatttg aactttatat tcagcttttg atgtatataa agcttgttta tctgtattta
    40381 ctgatataaa ttcaacgcct tttagttgag cttctaccat tctattgaca gcattgtttc
    40441 caccgccacc tacacctatt actttaattt gtgcacattc ttctaattct acgtcaaagt
    40501 ttagcatcat aaaccccctt ctctcatgat tcaaagttat cgtatgtatt aattatatca
    40561 ttttcttctt ttattttgtt aacctttaag taacatattc cacaaaaacg taaattttcc
    40621 tttttaaatt tcttacttat attgtcaaat attactcttt aagtataaaa taatttacgt
    40681 atatattaaa tgctctttaa tttttacgtt ttttgttcat aatattacta ataatatatc
    40741 gtctaattat agataagtta ttaaacaatc tcataccaaa aactaataca gcaacatagt
    40801 aaagagaaac tcctaacttt tctcctatat aagtcaataa tatagccaat atagcattac
    40861 ctatgaaacc agtaataaaa attacattat catagttatc ttcaaaattg gattttatcg
    40921 ctccaaaaat agaatccatt attgcaagaa tagctactga catatatatg gaataatcca
    40981 tagaatatgt aaatggaata tagtaaccta ctactacacc aaatgctaat cctcctaaaa
    41041 cccataacat aaatcttcac ctctttattt tactttgaaa cacaactaca ttacaatcct
    41101 ttttattaat tttttttact ttttctttat ttttttgtat ttttcgtttt attttgcaaa
    41161 taaattcact ttatttccat tattttcctg aacttttata ttaattccat atatatcctt
    41221 aagagattta gcatatgatt ctggagagtt tatagctgca ctcaataaat ctatatctcc
    41281 tatagctttt attataaatg gttgtccata tgtagtatca tttactgtaa tagtagctcc
    41341 tgaacatttt atcttacttg ttgctagtac tctttctcca tttatagaaa ttgctcttgc
    41401 tccagccttt tttaaatcat ttaaaaccct caaaatatct atatcatgta taatcaaatc
    41461 gtttggattc tgtccgtctt ttaactctct ctcactatcc ctcatagtaa tagttatgcc
    41521 tggccctgta acagttgaat aaccacttaa ttctttaact tcttcaagct ctttttgcat
    41581 aagtgtttgg atagattcat ttccattctt ttttgcttct ttatattcat tcaaagtttt
    41641 tttgttgttt ttaagagttt cttttaaatt ttttatttct ttttttgtat tttctacctc
    41701 actttcaata ctttcagttt gacctaatgt tatgtatact ctatttgggt ctagtgattt
    41761 tatataagtt gatatgaaaa cgcctaatat gaatgctcct aatataacta ttttcttttt
    41821 catactatta tttcccctct gctttgttta tatcactatg accatttatt tctatattgt
    41881 cttctttggt cacttttact ttggcattat aatatgtttc tatttcccag acaataccat
    41941 actttatatt aagtgctgaa gccaatgtat cagaatcacc aattgctttt attataattg
    42001 gttcttttat gacagtgtca ttcatataaa gcttgtcttc ttttaaatac atatatgtat
    42061 tagaaactat tctctggtcg tttatagata tggcacttgc ttgtgctgaa tttaatttat
    42121 ttatcattga taataataaa tcataattat atagtatact atcattttta tcagagtttc
    42181 ctaagtcttt tgtagaattt atctcaattt ttatgcctgt tccttcaaca tctgtatatc
    42241 cagctaatgt ttcatatttt tctatttctg acttaagtat gtcttgttct ccttcattgt
    42301 ttttgcctct ataagtctct atatctttct tcacactatt aacttctgat tgtagattct
    42361 ctttttcttt ttttaaagat ttaagttctt ctgtaagttg ctctcctctt ttaaaagttg
    42421 tcatccctct attttctata ttaataattt taagttgtaa actaacaaga acacccaata
    42481 caatacttcc tatgattata cttttattta taaatctttt tttcaatata tcacttcctt
    42541 acaattgtct atccttctgg actatacact gccaactttc catagttaag atttatagtc
    42601 cctccattag tatttttatt ttgcaggtca atcagaattt tacttaccct agatatatta
    42661 taatctaagt tatcatcatt agaaagtaag atttttatat tacttcttgt aagtatttct
    42721 atattgcttt ctttttttaa gtttacataa tttatttttc tataaattcc ttcttctttt
    42781 aaataattta a
//
LOCUS       DAGQVA010000028        42639 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.028, whole genome shotgun sequence.
ACCESSION   DAGQVA010000028 DAGQVA010000000
VERSION     DAGQVA010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42639
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.028"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..295
                     /locus_tag="MIV85_001682"
     CDS             <1..295
                     /locus_tag="MIV85_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBY2961023.1"
                     /translation="KGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVE
                     KAADKIIYIPNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            747..2042
                     /locus_tag="MIV85_001683"
     CDS             747..2042
                     /locus_tag="MIV85_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBY2961024.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            2484..3221
                     /locus_tag="MIV85_001684"
     CDS             2484..3221
                     /locus_tag="MIV85_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBY2961025.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            3242..4495
                     /gene="murA"
                     /locus_tag="MIV85_001685"
     CDS             3242..4495
                     /gene="murA"
                     /locus_tag="MIV85_001685"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBY2961026.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            4582..5646
                     /gene="spoIID"
                     /locus_tag="MIV85_001686"
     CDS             4582..5646
                     /gene="spoIID"
                     /locus_tag="MIV85_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBY2961027.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            5712..6380
                     /locus_tag="MIV85_001687"
     CDS             5712..6380
                     /locus_tag="MIV85_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBY2961028.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            6478..6738
                     /gene="spoIIID"
                     /locus_tag="MIV85_001688"
     CDS             6478..6738
                     /gene="spoIIID"
                     /locus_tag="MIV85_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBY2961029.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            6935..7954
                     /locus_tag="MIV85_001689"
     CDS             6935..7954
                     /locus_tag="MIV85_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBY2961030.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            7970..8398
                     /gene="fabZ"
                     /locus_tag="MIV85_001690"
     CDS             7970..8398
                     /gene="fabZ"
                     /locus_tag="MIV85_001690"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBY2961031.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(8509..9018)
                     /gene="yyaC"
                     /locus_tag="MIV85_001691"
     CDS             complement(8509..9018)
                     /gene="yyaC"
                     /locus_tag="MIV85_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBY2961032.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      9207..9310
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            9447..10640
                     /locus_tag="MIV85_001692"
     CDS             9447..10640
                     /locus_tag="MIV85_001692"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBY2961033.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            10956..12053
                     /locus_tag="MIV85_001693"
     CDS             10956..12053
                     /locus_tag="MIV85_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961034.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRISMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTGGYKENKSEIS"
     gene            12317..14536
                     /locus_tag="MIV85_001694"
     CDS             12317..14536
                     /locus_tag="MIV85_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBY2961035.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            14539..15321
                     /locus_tag="MIV85_001695"
     CDS             14539..15321
                     /locus_tag="MIV85_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBY2961036.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKIVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKDNVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            15653..17566
                     /locus_tag="MIV85_001696"
     CDS             15653..17566
                     /locus_tag="MIV85_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2961037.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            17707..18015
                     /locus_tag="MIV85_001697"
     CDS             17707..18015
                     /locus_tag="MIV85_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBY2961038.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            18039..18365
                     /locus_tag="MIV85_001698"
     CDS             18039..18365
                     /locus_tag="MIV85_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2961039.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            18404..19738
                     /gene="celB"
                     /locus_tag="MIV85_001699"
     CDS             18404..19738
                     /gene="celB"
                     /locus_tag="MIV85_001699"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBY2961040.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            19749..20270
                     /locus_tag="MIV85_001700"
     CDS             19749..20270
                     /locus_tag="MIV85_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBY2961041.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCYQ"
     gene            20363..21322
                     /locus_tag="MIV85_001701"
     CDS             20363..21322
                     /locus_tag="MIV85_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBY2961042.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            21371..22423
                     /locus_tag="MIV85_001702"
     CDS             21371..22423
                     /locus_tag="MIV85_001702"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBY2961043.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            22426..23100
                     /locus_tag="MIV85_001703"
     CDS             22426..23100
                     /locus_tag="MIV85_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBY2961044.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDIGVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            23653..24204
                     /gene="raiA"
                     /locus_tag="MIV85_001704"
     CDS             23653..24204
                     /gene="raiA"
                     /locus_tag="MIV85_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBY2961045.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            24336..27011
                     /gene="secA"
                     /locus_tag="MIV85_001705"
     CDS             24336..27011
                     /gene="secA"
                     /locus_tag="MIV85_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBY2961046.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            27026..28133
                     /gene="prfB"
                     /locus_tag="MIV85_001706"
     CDS             join(27026..27100,27102..28133)
                     /gene="prfB"
                     /locus_tag="MIV85_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBY2961047.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            28277..30418
                     /locus_tag="MIV85_001707"
     CDS             28277..30418
                     /locus_tag="MIV85_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBY2961048.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DNEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKTIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNICEIDEKIKEIGLRELSEKLEVGQVTLKDIITEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            30566..31732
                     /locus_tag="MIV85_001708"
     CDS             30566..31732
                     /locus_tag="MIV85_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2961049.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      31792..31909
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            32033..32638
                     /locus_tag="MIV85_001709"
     CDS             32033..32638
                     /locus_tag="MIV85_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBY2961050.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPFVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            32967..34007
                     /locus_tag="MIV85_001710"
     CDS             32967..34007
                     /locus_tag="MIV85_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBY2961051.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMESVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            34146..34598
                     /gene="tsaE"
                     /locus_tag="MIV85_001711"
     CDS             34146..34598
                     /gene="tsaE"
                     /locus_tag="MIV85_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBY2961052.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            34598..35314
                     /gene="tsaB"
                     /locus_tag="MIV85_001712"
     CDS             34598..35314
                     /gene="tsaB"
                     /locus_tag="MIV85_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBY2961053.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKITHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVDFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            35304..35780
                     /gene="rimI"
                     /locus_tag="MIV85_001713"
     CDS             35304..35780
                     /gene="rimI"
                     /locus_tag="MIV85_001713"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBY2961054.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            35786..36802
                     /gene="tsaD"
                     /locus_tag="MIV85_001714"
     CDS             35786..36802
                     /gene="tsaD"
                     /locus_tag="MIV85_001714"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBY2961055.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREILSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            37099..39807
                     /gene="hpdB"
                     /locus_tag="MIV85_001715"
     CDS             37099..39807
                     /gene="hpdB"
                     /locus_tag="MIV85_001715"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBY2961056.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            39811..40068
                     /gene="hpdC"
                     /locus_tag="MIV85_001716"
     CDS             39811..40068
                     /gene="hpdC"
                     /locus_tag="MIV85_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBY2961057.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            40061..41011
                     /gene="hpdA"
                     /locus_tag="MIV85_001717"
     CDS             40061..41011
                     /gene="hpdA"
                     /locus_tag="MIV85_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBY2961058.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSVENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            41327..42289
                     /locus_tag="MIV85_001718"
     CDS             41327..42289
                     /locus_tag="MIV85_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBY2961059.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(42388..>42639)
                     /locus_tag="MIV85_001719"
     CDS             complement(42388..>42639)
                     /locus_tag="MIV85_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBY2961060.1"
                     /translation="PILGLILRSIHIVGISIFLGYLYIKTKNIWFCAIIHILNNSAFL
                     ITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        17280 a         4442 c         7990 g        12927 t
ORIGIN      
        1 aaaaggaact cctgtaattg ccatagctac tcaagaaaag ttatttgaaa aaatggtttc
       61 taatatggaa gaagtaagag caagaggagc ttatgtagta gcaatagctc aaagccataa
      121 taaggatgtt gagaaagctg ctgataaaat aatctatata ccaaattcag atgatatttt
      181 atcaccaata ttagcagttg taccaatgca attacttgct tatcatgtct ctgtactaag
      241 aggatgcgat gtagataagc caagaaatct agctaaatca gtaacagttg aataaaaaca
      301 gattaaaaat taaatagata atatttattg aaaagaactc atcctgttat ttgtatttta
      361 taggatgagt tttttagata aatattaaat ttgttttgtt tttgctataa taaattttat
      421 aaaaagattg atattaaatc atctgtaaaa tgataaatat atagaccata ccaggtatag
      481 ggaacgataa atatagttca cataaaatat agtgagtact taataaacat atagtcaata
      541 tcagataaaa aaaataatag cttatgagaa aaattaaaat acaaggtatt agtaaccttg
      601 tgataagata aagtgagtag tttaaaataa gaatataagg aactatttat aaaagaatat
      661 aatgaagcta atagagtata agaaaattac tttattttag taaaataatt tcaaataaaa
      721 atttttttaa attgggagta taaattatga caaatgattt taaaaaagaa aagaaagaag
      781 attattttgt taatcttaag gcaatatcta ctgaagtttt acaagaaaaa gtgcaagata
      841 acgcttgggt tatagttgat actcgcttaa atgatgctta taatggctgg aagttagatg
      901 gagtaaaaag aggtggacat ataaaaggag cagtagattt ttctgctaat tggttaagtg
      961 tatactcaga tagaaaagat gaagtgttag aacaagcatt gaaaactaaa agaattgatt
     1021 tagataaaaa tatagtattg tatgatgcaa atggaaaaga tgctttggtt gtagcagatt
     1081 atttatctaa aaaaggatat aaatatctat ataaatatga tattaaacaa tgggcagacg
     1141 acgaaaatct tccaatggaa agatataaaa attatcaaat gatagttcct gcttttataa
     1201 taaaagatat attagatgga aaaattcctg agacatttga agattcaaag aatataaaaa
     1261 tgattgaagc gagttgggga gaagaatcgt atacaaaagg gcatatacct acaagtgttc
     1321 atgtaaatac tgatattata gaacctcctc caacatggat gcttgataat gatgataact
     1381 taactaagtt tgctttagac tatggattaa caaaggatga tactgtaata gtttcaagta
     1441 gtacacctat ggcatcttat agactagctg ttatattgag atatatagga gtaaaagatg
     1501 taagagtttt gaatggtgga acaaactcat ggttatcagc aggatatgaa ttagaattta
     1561 ttagtaatcc aaaacattca tgtactaatt ttggagcaga tataccagtt aactcacaat
     1621 taattgttac tacatctgaa ttaagacaaa aactaaaaga aaaaaataag tttatactag
     1681 tagataaccg tacttgggat gaacatatag gaaaagtatc tggatataca tattatgata
     1741 aaaaagggcg tataccagga gctttatatg gacattcagg tagtgatagt gtttcactag
     1801 aagaatatcg taatattgat aatacaatga gaaataaata tgagatttta gaaatgtggg
     1861 acaaggaaaa tatagatgtg aataaacagc ttatatttat gtgtggaagt ggatggcgtg
     1921 ctgctgaagt attaacatat gcaaatgtca taggagtgga aaatacctcc ctttatagtg
     1981 atggatggat gggctggagt cttgataatt caaatttaat tgaagtggga gaacacaaat
     2041 aaagtttttg aaagtgcaat agagttgttt aaaacaaagg tgtttttgat ttattaggaa
     2101 gagtgtgtaa attgtgtatt gggaagtgta cttaggtatg ttcatttgga gctatggaaa
     2161 ttgataaaaa agtattatct gtttattttg ttggtaaaat atgaatagat tatagattat
     2221 agattataga tttaagtata gactaagtaa tttatattac agaagagaat atataagaat
     2281 taatgcaaga tgtatttgat acatataaga aattggcaag tccaggagaa ggatagagaa
     2341 aattgagatt gaagagtttg aaagagatta ttagatgaaa aatacaaaaa tgtataaaaa
     2401 tacatattga gaaagtatat ctctcttaaa tttgttaata attctattat acagaaaaac
     2461 atatttaagg gggatttttt actatgaaaa aagtaaaatt agctataagc ttttttatat
     2521 taatgattat aggaatgaca atatcttatg cagatacaag tataaatact agatacaata
     2581 gattaagtaa agctcttgaa atatcagaag caaattttaa attttataat gttaaaatta
     2641 attctgttat aaatcataat ttatcaaata aagaatttca taatattttt atagaaataa
     2701 ttaacaatct aaagttggat aaaaaaggaa taaattggaa tcaaaaaggg tctggcgata
     2761 aaatacaatt atgtgctact ataaaaggta gcgataaaga aatttctata aaaggaataa
     2821 ataaaaataa caaagaaagt tacatagtag ttgacatatt ggataacaaa gtatataaac
     2881 ataaagaggt tatttatagt aacgtagaaa atgtgttaaa taaatattca tctcaagtag
     2941 atgtgtctgc ttgtattgtt ggagaataca caaaaaggtt acaaaacaac aaatatgatg
     3001 atattttaca aaaaatatta tataatatga gtgctaagca aatagatgaa gttaaagacg
     3061 taaacttttt atctataaca gcatatagta aagtattaaa tgattatgaa ttagaatatt
     3121 taggggaaaa aattaattta aatataggaa ttaaatataa tgaggatgac ggaaaaacac
     3181 tcatatatat tgccacacca attataaaat tagattatta attatgagga gatcaaaaaa
     3241 tatggctaag ataatagtaa aaaagagtaa tccacttaaa ggtagtgtta aaatagatgg
     3301 tgcaaaaaat gcagttttac caataatagc agcgacttta ttagcaaacg gaaaatcaac
     3361 attaaatgga gtaccaaatt taagagatgt tcatgttata tcagatttat taagacatgt
     3421 aggagcagaa gttgaatata aagaaaatac acttactgtt gatgcaagca atataaaaac
     3481 ttgtgaagct ccatatgagc ttgtaagaaa gatgagagct tcttttttgg ttatgggacc
     3541 attgcttgct agatttaata gtacgaaaat ttctatgcca ggaggatgtg ctataggaac
     3601 aagacctata gatttacatt taaaaggatt taaagcttta ggtgcaaaga tagaaatgga
     3661 ccatggtttt gttgaagcag caacagaaaa gttagtagga aataaattat atttagattt
     3721 cccatctgtt ggagcaactg aaaacataat gatggcagct tctttagcag aagggactac
     3781 aataatagag aatgcagcag aagagccaga aatagtagat ttagcaaact tcttgaacga
     3841 aatgggagca gatgttaaag gtgcaggtac taatactata aaaataaaag gtgttaaaga
     3901 gttaaaagga gcagaacata atgtaattcc agacagaata gaagcagcaa cttatatggt
     3961 tgcagcagct atgacaaaag gtgatataac tgttgaaaat gttttaatgg agcatttaaa
     4021 accagttgta gctaaattaa gagaagctgg ttgtgaaata acagaaatgg acaattctgt
     4081 aagagttgta ggtccaaaag tattaaaacc aatagatata aaaactttac cacatccagg
     4141 atttcctaca gatgttcaag cacaatttat ggctatgctt actgtagcca atggaactgg
     4201 tgtagttata gaaactgttt ttgaaaacag atttatgcat gttgctgaat ttaatagaat
     4261 gggtgctaat ataaaaatag atggaagaag tgcggttgtt aatggtgtag atgagctaca
     4321 cggtgcagca gtaaacgcta ctgatttaag agcaggggca gcccttattt tatgcggtct
     4381 tatagcagaa ggagaaactc aaataggaga aatataccat atccaaagag gttatgttga
     4441 tatagataag aagataacag cactaggtgg tcaaatcgaa atagtagaag attaataatt
     4501 ggtttataga agaaagttat aaattaatag ggttgttcat atacttaaat acaaggtttt
     4561 aaaagctaag gaggagagta tatgaagaac ccattggttg ttttgttagg atttgtgact
     4621 tgctctgtgt tagttccatc acttataact ttagtttctt ataaaaatgt agaattaact
     4681 gaaaaaccag agagcccagt atctataaac aaaactatta aaaaaagtga tattgaagac
     4741 aaaggtaata aagaagaaaa aaatacagtg aactatgaaa ctgtaaataa aaaagcacca
     4801 attatcaatg tatataatca cataacaggg aaaaccgaaa agatggacat ggagaactat
     4861 ttatgtggag tactagctgg tgagatgtct tcagagtttg atatagaagc tttaaaagct
     4921 caatctgtag cagctagaac atatgtagta tataaacagg aacatggtaa atctagtaaa
     4981 cataaaaatg cagtagtatg tactgattat aaacattgtc aagaatataa gagttatgat
     5041 actcttaaaa aattaaatgg tgaagaatgg attaagaata aatattccaa aatccaagaa
     5101 gcagttagag gaactaaagg tcaaataata acttataatg ataaggcgat acttcctctt
     5161 tatttttcta catcttcagg aaaaacagaa aatagtgaag aagtattttc tgcaaaatat
     5221 ccttatttaa agtctgtgga aagtccttat gataagtatt cccctaaatt tgcgtcaaca
     5281 cttaaaataa gtaacacaga ttttgttaaa agtcttagaa gggcatatag cactattgtg
     5341 atagatgtga ataatttaag taaacaagtt tcaataacta aaagaagtga tgccggaact
     5401 gtagaaaaaa taaaattagg aaataaagaa ttgactggaa aagacattag aactgttttt
     5461 aaattgaact ctgcaaactt tgacataaaa tttggagaag gatacataga tttcgtggta
     5521 aaaggatatg gtcatggtgt tggtatgagc cagtggggag cagaaggaat ggcagaagag
     5581 ggctataaat attatgatat attatcacat tactacacag atacaaaaat aaaagatata
     5641 tactaataat tgtataaaat gccaaaaaca cgtcaataat ccaaatgtag aaatatattt
     5701 ggaggtgcaa aatgaagaaa aagctgttag aaaaagatgg tttttattta tctttgtttg
     5761 tatgtgtttg tttattagca gtaggtggag tttggtttac aaataataat gtagataaat
     5821 tggcttctaa taaaggaatt atggaaaatg ctaataaaga tagtgaagag gaaatacatt
     5881 taattgaaaa agacaagaaa gatgctatcc ctactgcaac ggattcaaaa caaaacttag
     5941 aaaaagctaa gtcaaaagag gaaaataaat cgagtacaac aaaattaaat tacattggag
     6001 ataaagtaat aagaggatat tcagaaaaag agcctagtta ttctaaaaca cttgatgttt
     6061 gggaaactca taaaggtgta gatattagtt gtactaaagg caaagaagta aaatctctat
     6121 taaacggaat agtagtagat gtatttgatg atgaagaata tggacaatca gtcaaaataa
     6181 aaagtgacaa taacattgta gtagtatatt caaatctaga taaaaatgtt agtgttaaga
     6241 aagaacagaa ggtaacagaa ggacaatctc taggtactgt aggtagtact tctcaaatag
     6301 aaagtgaaga aggtatacat gtgcatttag aggcgtatag tggagaaaaa tctatagacc
     6361 caatgagtct aattaagtaa tagtataaca agtttaatca tatttggtta agcttgttat
     6421 attttttggt gtttttacat atatatcatt aaagctatta tgtgaggggg gtaatctttg
     6481 agatctcata tagaggaaag ggccatagtg gtagcaaaat atatacttga aaaaaacact
     6541 acagtaagac aaaccgccaa gacatttgga gtaagtaaaa gtacaattca taaggatgtt
     6601 acagaaagat tgaaggaaat aaatccatcc cttgccaaag aagttaaaaa tgtgctggac
     6661 aaaaataaat cagagagaca tattagaggg ggattagcaa cgaaattaaa atatgagaag
     6721 gaacataaaa aaatgtaggt taaaaaccta ctttttttat tgaattaaat tataaaaaga
     6781 aatatattaa gtaattataa atagcaaaat aataatactc tcaaaagatt tattttctct
     6841 tgattaaagc gagatttttg tatatgcttt attataggag tattaaaata ggcttataat
     6901 ataatctaat attataaata aaggagttga aaaaatggct ggagctgata taggcataga
     6961 tttaggtact gcaaatgtgc ttgtttatgt tagtggtaag ggaatcgttt tagaagaacc
     7021 atctgttgtg gcgatagaca aaagaacaga ttctgtttta gctgtgggag aagaagctaa
     7081 aaagatgata gggagaacac caggtaatat agtcgctata agacctttaa gagatggtgt
     7141 aatttcagat tatgatgtaa ctgagaagat gttaaaatct tttatagata agatagttga
     7201 taaaaaggga tttggaagat tttttatgcc aagaattatg gtatgtgtac caacaggtgt
     7261 cacagaagtg gaaaaaagag cagtagaaga tgctacgaga caagctggag ctagagaagt
     7321 atatatcata gaagaaccaa tagcagctgc cataggagct ggtgtagaca tatcacagcc
     7381 taatggtaat atgattatag atattggtgg aggtactgta gatatagctg taatatctct
     7441 aggaggagct gttgtaagtg aatctataaa ggttggtgga gatagatttg atgatgctat
     7501 agttaaatat atgaaaaaac aacacaatct tcttatagga gaaagaacag cagagaaaat
     7561 caagtttgaa ataggttctg catttaagag agaagaagaa aaatatatga agataacagg
     7621 aagaaattta attacaggac ttcctagttc tataactata aattcaacag aaatgttgga
     7681 agcacttaga gaatgtgttg agcaaatagt agttgctact catgctgttt tggaaaaaac
     7741 gcctcctgag ttagcagcag atataggaga tgtcggtata ataatgactg gaggaggttc
     7801 attattatat ggattagata aaataataga acagaggaca ggaataactg ttacaatagc
     7861 agatgaacca ttatcttgtg ttgcaaaagg tacaggaata gctttaggtt caatagactt
     7921 acttgaaact ggtgggtctt tcaaaagaaa ataattagga gagtttagaa tgttaaatat
     7981 agatgaaata aaaaaattaa taccacatag atatccattt ttattagtag acaagattac
     8041 agagctagaa gttgggaaaa gagctgttgg tataaagaat gtaacagtta atgaaccatt
     8101 tttccaaggt cactttccag aatatccttt gatgccagga gtactaatag tagaagctct
     8161 agcacaagta tgtggagtgg caatgatgtc tgtagaggaa aacaaaggaa aactaggtgt
     8221 atttgcaggt atagataaag ttagaatcaa gagagaagta agaccaggag atacattaac
     8281 tatggaagtt gaaatgacaa ctcttagaaa aaatatagct aaggcagatg ctaaggcata
     8341 tgtaggtgaa gaacttgtct gtaaaggtga attaatgttt gctttagtag aaaaataaaa
     8401 acttgaaata taaaagtaaa aaggtagata atttggagta tttaatcaga tactctaaaa
     8461 tatctacctt tttatataaa gaattttatc atttagttta tatttagatt aggtggatac
     8521 taataaagcc aaggctattg tttcagctaa atctaatata aagctaaggc gtatattatt
     8581 aaatgaaagt ttattatttt catcaatttt atctacaatt cctactatag aataatttcc
     8641 tatttgaggt agttttttac caacaccttt tccgggcagg ataggtcctt ctctaatctg
     8701 tatattacct atgttactct gcgaccccaa gcaagcatct atagccaaga agttaccttg
     8761 tatatgtgta ttttttatag tatctaaaga ctcatatata tttaaggcgt gaatagggtt
     8821 atctagtgta ccgtaaacgg ggtatttaaa gttactgttc ttaagtattg ttccaactaa
     8881 agggcctaaa gtatcaccta tagccctgtc tgttcctatg caaacaacaa tcgtattttc
     8941 attaattata gtttttagaa ctgaacttag catctgtata acatcatcat cgctgtagtt
     9001 tactttagct aaatacaata ggaacacccc cttcaaaaaa atatatgaat aaaaagcatt
     9061 aaaaagacct aactttaaat ttcagataga tagaaaattt tatttgtctt acaaaaaaag
     9121 gaatagaaaa aatatgacta aaaatattga caaaatttta aaaaaatagt aagctagtaa
     9181 agtaaaacaa aacttaaatc ttgattacct tatcaagaga ggctgaggga taggccctgt
     9241 gaagcccagc aaccacccaa atgggaaaag gtgctaattc ctacaagaca aaagtcttga
     9301 aagatgaggt cagttaatta gtatgtaatt acgattatta acctcttctt ataaaggaga
     9361 ggttttttta ttttgagtaa atttctaaaa ttaaaaataa ggtaaaacct ataataaaaa
     9421 ttaagaataa ataaggggga ataaaaatgg caagacattt atttacgtca gaatcagtta
     9481 cagaaggaca tcctgataag atatgtgacc aaatatcaga ttcaatatta gatgcattat
     9541 tagaaaaaga cccacaatct agagtagctt gtgaaactac agttactact ggtttagttt
     9601 tagtagcagg agaaataagt acatctgctt atgtagacat tcctaaatta gtaagagaaa
     9661 cagtaagaga aattggatat acaagagcaa aatatggatt tgattgtgat acttgcgcag
     9721 ttataacttc tattgatgaa caatctggag atatagctat gggagttgat gaaggcctag
     9781 aaagtaagac tggagaagag atagaagaag aaatagaaaa agttggagct ggagaccaag
     9841 gtataatgtt tggatttgca tgtaatgaga ctccagaatt aatgccactt ccgatatctt
     9901 tggcacataa attatcaaga agacttacag aagttagaaa aacaggttta gttgattatt
     9961 taagaccaga tggaaaaact caagttactg ttgaatatga aggaagtaaa gctgtaagag
    10021 tacatacagt tcttatatca gctcaacatt gtgaaacagt atcaaatgat aaaataagag
    10081 aagatttaat taatcatgtt attaaggaag ttataccagc agaattactt gatgaagaga
    10141 ctaaaattta tataaatcca acaggaagat tcgttatagg aggaccacaa ggagatacag
    10201 gtcttacagg aagaaaaata ataatagata cttatggtgg atattctaga catggtggag
    10261 gagctttctc aggaaaagac cctacaaaag ttgatagatc tgctgcttac gcagctagat
    10321 atgttgcaaa aaatattgtt gcggctggtc ttgcagacaa atgtgagata gaacttgcat
    10381 atgctatagg tatagctaga ccattatcta tatttataga tacttttggg acaggcaagg
    10441 tttcagaaga aaaacttgtt gaattagtaa ataaacactt tgatttaaga ccaggagcga
    10501 taataagaga cttagattta agaaagcctc tttataaaaa ggttgctgct tatggtcact
    10561 ttggtagaac tgatatagat ttaccttggg aaagaactga caaggttgag cagttaagaa
    10621 aagatgcttt aggtgaataa tttttaacta aaaagctgtt agaatgtaat tttatgatta
    10681 ctttctaaca gcttttttat tatgagttaa atatttttaa taaatgttaa tttatcatca
    10741 tataatgaat aaacagtatt taatctggtc aatacatttt atataatact ctactaaatt
    10801 tatacatatt atgggatata tgttaaagga tggttaagaa tgtgttaact aatgttaaat
    10861 aattaaaaat atattgaaat atcacaataa tgagtctaat ataatcttaa taaacttaca
    10921 ctttaaaaat aattttaatt gggggggagt agtgtatgtc aggcaaagta aatattaaaa
    10981 cggttataag ttttgctgga gcttatgttg ctactgtaat aggttctgga tttgcaactg
    11041 gtcaagaaat actgcaattt tttacgtttt atggatatgc gggtattata ggtggaataa
    11101 tctctatggt actattttca tggtttggag cagaagttat agataaggga agagaattga
    11161 aacttaagga gccaataaaa atttatcaag tatattgtgg aaaatatctt ggaacatttt
    11221 ttgaatggtt tggtccattg tttttatttg gaacattagt aataatgatt gcaggagcag
    11281 gagctacatt atcagagtac tatggattaa atccatatgt aggtaggatt agtatggcaa
    11341 tcgtttccct aataactgtt tcattaggtt tgacaaggct ttctaaaata ctaggtaata
    11401 taggacctat aataataata tttacacttt tagtaggagc aattagttta tttagcaata
    11461 ttgatgcttt atcaaatgct ggaaatatgg ttgatagttt aaatattaaa actgctacat
    11521 caaatggata tttctcggga gtactttata cttgttacaa tgtaataata gtaataacat
    11581 tcttgacagg aatgggagct tctgcagtaa ataagaaaga tgctgtatgg ggtggtatag
    11641 taggtggagt agcacttatg gcagcagcta taatgatgaa tttggcatta ctttcagaca
    11701 taggaaatat atacacaaaa gagataccag cactttactt agctgataag atatctccaa
    11761 taataggtat tttattctca gtagtacttt tactaggaat atacactaca gctgtaccat
    11821 tgttatggtc agtaacaaac cgatttgtag aagatgacca ccctaagttt aaaattataa
    11881 caatagtggt aagtatatta gcttgtatag gaggtttact gccatttgat aagttagtag
    11941 gtacactata tccatataca ggttacatgg gaattttaat tttactatgt atgctttata
    12001 gaagaattac taaaactggg gggtacaagg agaataaatc tgaaataagt tagtactgta
    12061 atatacttat gaaatttaat ttatactcta aatatagagt aactaaaata aaatagctat
    12121 ttaaatatgg tacctgtatt tcatggtacc atattttatg gatgcagatt ttttttgttt
    12181 ctgataaaat gtataatagt tggaaattac gttaagtata aaaatataaa acttttctac
    12241 gattatcata gttttaatat ataaaattat actaacattt aaatggagcg attattagta
    12301 tttttaggag ataaaaatgg aaaaattaga aggaatgata agtgaaatag tctttaaaaa
    12361 cgaagataat ggttatacaa tagctcacct ggtaaatgaa aatgatgaaa ttgtggttgt
    12421 aggatgtatg cctactttgg caattggaga aagcatagaa gttgaaggaa agtgggtaaa
    12481 tcataagatt tatgggactc aatttgaagt gaatagtttt atgccagtaa caccatcatc
    12541 cttagaagga atttatgttt acttatcttc tggaatgata catggtattg gtgaaaaaat
    12601 ggcaaaaaga ataattgata agtttggtgt agatacgtta gaggtgatac aaaattcacc
    12661 agaaaaacta caagaagtag aaggcatagg gagtaaaaaa gtaaaacaaa tagtaaaaag
    12721 ttatgaagaa gacagagaat tgagaaatat aataatacag ctatctcctt ttggaataac
    12781 accaaattac tgcctaaaaa tatataaaaa atataaaagc agtgcaatag aagttataaa
    12841 taaaaaccca taccaacttg ctgaagatat aagaggaatt ggatttaaag tagctgatag
    12901 tatagcaagt aaaattggta tagataaaaa ctctaaagat agaatttgtc agggaatctt
    12961 atacacttta aataaatctt taagtaatgg gcatacatat ttaccagagc atgttctaat
    13021 acaagattcg gaaaaattat tggagctaaa tggagaaata ataaaagagt gtgtaatgat
    13081 gctagtttat aatcaaaaaa tacatataga gaaagtaaac aatgaaaatc ttatatacct
    13141 tatgccatac tatttagctg aaaatggagt atgtagtcaa atagtaaaat tatcacagta
    13201 tgaatttgaa gacttaaaaa tagatataga taacgagatt aatgttttag aagaagataa
    13261 gaaaattaag ttagcagaaa aacaaatttt agcagtcaaa gaatctgtta atagtggagt
    13321 attaattata actggtggac caggaactgg taaaacaact accattaatg ctatcataga
    13381 tatatttgaa aataatggta aaagtgtgac tttagcagct ccaacgggaa gagcagcaaa
    13441 gagaatgagt gaaacttcta ataaagaagc aaaaactata cataggttgc tagaaatggg
    13501 attttcaaca gatgatgatt taactttttt taaggatgaa gaagacccaa taaattcaga
    13561 tgtaataatt gttgatgagg tatcaatggt agacattatc ttaatgtaca atttacttag
    13621 agctataaag ttaggaacaa gagtaatttt agttggagat agtgaccaat taccttctgt
    13681 aggtgctgga aatgtactta aggatatgat taattctaat atcataaatg tagttaaatt
    13741 aaatgaaata tttagacaag cgcaagaaag tatgataatt gtaaatgccc ataagataaa
    13801 caatggagaa ccactttatc taaatacaaa aggtaaagat ttctttttta taagaaaatc
    13861 aactaatgaa gaaattttaa atgaaataat aggattggtt aatgaaagat tacctaaatt
    13921 ttataaagtt gataaattaa aagatataca agttttatct tcaatgagaa aaggtgaatt
    13981 gggagttact aatctcaata tagagttaca gaagtatctt aacaaaaaag aaaaatttaa
    14041 agttgaagaa agtttttcta aaagattatt tagagttggc gataaggtaa tgcaagtaaa
    14101 aaacaattat acaaaaaaat gggaaacaga agaccaaaaa gaaagtggag aaggtatcta
    14161 taatggagat ataggatatg tttatcacat agataaagat aagaaaacta tttatatatt
    14221 atttgaccag actaaaattg tatcatacct atatgatgaa ttagatgaaa ttgaccatag
    14281 tttttgtaca acaatacata aaagccaggg aagtgaattt ccagttgtag tattgccaat
    14341 agcgtgggct cctcctatgt tacttagccg taatttatta tatacagcag taacaagagc
    14401 aaaaaaatta gttgtattag ttggagatgt gaaatatctt gaatatatga taaaaaataa
    14461 tagagttaat caaaggtatt caaatttagg atataagcta aataaattta aacaagaagg
    14521 gttgttgata gaataaatat gaaaatatgc aatgataatt ttattaagaa ttttaaaaat
    14581 atgattaata aatgtttgga ttttatatat cctgagaata taagttgcat aatttgtgat
    14641 aaatccataa agaaaacaaa tacttattca atatgtaaaa gttgttttaa agaaatgaat
    14701 tttatacaag atggttgcat gaagtgtgga aaaccaataa tacgtcattc aattgaaaaa
    14761 gaatttattg aagaatgtag ttattgtttt aataaagact tttattttga taaatcaata
    14821 tcttgtattg aatacaatga tgtgacaaaa aagatagtgc tagggctgaa gtataaccaa
    14881 aaaaccttta tggctaagta tatagctcaa ataatgaaag aaaaattata tttagaaaac
    14941 ataaaatttg attatatatt atttgttcca cttcataaaa aaaggctaaa taaaagaggt
    15001 tttaatcagg cacaaaaaat agcatttaat ttaagtaaaa tagtaaatat tccattatta
    15061 gattgcataa gtagaaaaaa atatacaaga atgctatata aattgaataa gaaagaacga
    15121 aaagaagaat taaaaaatgt atttgttgtt aaagacaatg ttaaattaat aaataataaa
    15181 aatatacttt taatagatga tatatttact actggtctaa caacaaacga aatttctaaa
    15241 cttttaaagt tatcgggtgc taataaggtt tttgtattga ctctacttac aaaagcaaat
    15301 gataattata ttatggaata atcttatata ttgacaattt taatttaaaa tattaaaatg
    15361 aataagtgat atttaggtct gtggttgaaa gtccaagcca gtcgcaggca aagggatcca
    15421 cgtaagttaa cactaaaaat tgggttaatg atcatggtgc ggcttagaag taagacctac
    15481 cgataataaa atcgagagag agtagtagtg cggcgaaccc aagcgaaccc tccagtaggc
    15541 gagtgtgggg tcaaaaacca ggtcagctaa atatcatatt aaaagagagc tagcatacct
    15601 ttatgtatag ctctttttta tatataataa atttaggttg agtcataaag aggtgatatg
    15661 tttgaataaa agacaagaaa atttattaac aacattgcta ttaaaagaag agtttataaa
    15721 tgttaataag attgccaatg attttgagtg ttcagaaagg acaataagaa atgattgcaa
    15781 atatattgat gaatggttat ctactttttg taatgcttat atcaaaagaa aacctaatat
    15841 tgggattaaa tttagtggag atggaacaga caaaatactg gtaaatcaga agttgcgagg
    15901 tgaagttaaa agagtaaata gtgagcttca taagcaagtt gagatattaa atttactact
    15961 ttgtaataat aaaaaagtta ctttaaatga tttatctaat aagttgtaca taaataaaaa
    16021 tattgtcaga gaagaaataa gtaaattatc agtagcatta aataattata atttaaatat
    16081 ctcgactaaa aaaggcagtg gtatatatat tgaaggggat gagaaagaca taagaataat
    16141 gttagtatca ttcttattta aatatataga taaatacaga ttaaacatag atgaaataga
    16201 gtacttccat atagtagata taataattgt aaaaaacata atgcttacta tagaggagga
    16261 tatggatata agacttacag atatatcatt caagcaattg atgctatttt tgcttataaa
    16321 tataatacga ataaggctgg gaaattcttt aaaagtatca aatactaaga aagagcttaa
    16381 gctaaaaatg cttatattgg atatagaaga tgaattgaaa tctaatttat ccatagtatt
    16441 aaattatgaa gaaaaattgt ttatagaatc tttaatattg ggtatgaaca aacaaataaa
    16501 tagtaataat attaagaaat ctttatatct aaatgaagaa ttagcaagtt atacaaaaaa
    16561 aattataaat ttagtatcag aagaatcagg aataaatttt aataatgata tattacttta
    16621 tgaacaatta atatgtcatt tgaatgttac aatgcatcaa atgaaaagca atgtttactt
    16681 agaaaatcca cttttagata acataaaaac taaattttgt tttttattta cagtaatatc
    16741 aagttcaata gaaattgaat taaaaggaaa acaaataacg gaagatgaaa ttggttatct
    16801 tacacttcac tttcaaacct ctctagaaag aaaatacagc aaaagggaat caaataaaaa
    16861 ggcaagtatt gtatgtccat ttagttttgg agtaagtatg ctattaaaag taaagataga
    16921 aaagagattt gataacataa aaattattga aacattaaga gaggaagatt taaaaagaga
    16981 taactttaat aagactatag attttataat tgcatttcaa gagtatgaaa atatccaaaa
    17041 accaattttt ataacaacac cattatttac tgatgaggat gagaataaac ttaaagagtt
    17101 cacaaacaaa ataaaagaaa aagacacttc atataaactt atgaacagat taatgatgtc
    17161 tgattattta ataagagagt tagaacatga tgatatttat gaagctataa catatttaac
    17221 taatttatta attgaaaaac attatgcaga aaaagagtat ttacaatcta ttataacaag
    17281 agaaaagtca tatccaacca atgttggaaa aggaatatta ttccctcatg gagacatgaa
    17341 atatataaaa caatctgttt tatgttttgc aaggttaaaa acaccaataa aaattagaaa
    17401 tggaaaggat ataaagatta tacttttgtt agcgtataaa aaagatgatg atagaaaagt
    17461 atttagagaa ttatttaaag aaatatctaa tttaacagag gatgaaaata tgctagatat
    17521 tctaagtaaa tgtgacattg aaaaggtaaa agatattctt atataaaatt catagtgaac
    17581 tatggataag cacaaaattt tccatgtgat ggaaaaagtt gtgcatgttt ttttgttttt
    17641 ataagatatt atatgtttgt aaggtataaa taatctaaaa gtagagaagc aacttaggag
    17701 gaaaaaatgg aagaaatagt tttaaagatt ataattcatg ctggaaatgc aaaatctatg
    17761 ctttatgaag cacttgacta tgcaaaggaa aacgatttta aaaaagcaga tgaattaatt
    17821 gaaaatgcaa atgaagaaat tttaaaagca cataaagtac aaactgaact tatacaaaag
    17881 gaagctgggg gagataaatc agatatatct attttattga ttcactctca agaccattta
    17941 atgacttgta tgagtgagag aaaccttata aaagaaatga ttatgttaag aaaagaaatt
    18001 caaaaattaa aataaaaaaa ttaaggggga tttaaaaaat gaaaagaaaa gtatatttat
    18061 tttgtagctt tggtatgtca acaagtttac ttgcagataa aatgcagaag gtagcagatg
    18121 aacacaattt accaatagaa gtagaggcat ttccgatagc agaaattgac aaaatagttg
    18181 aagaaaaaaa tccagattgt atattattag gaccacaagt taaatacatg ctaaaggagt
    18241 taaaaccaaa gtttgaagct caaggaaaac ttatagatat aatcaatgaa gttgattatg
    18301 gaactatgaa tggggaaaaa gtattaaaac ttgctataaa gctaataaaa tctaaacaag
    18361 cgtagaatta tagtaaaaaa taataggaaa tgagggtgga tagatgaata gattggaaag
    18421 aatacttatg ccattggctg aaaaaatagg taaaaataaa ttattaattg caattagaga
    18481 tggtttttta gtatcatcac cattattaat aataggttca ttatttttat tagtagcaaa
    18541 ttttcctata aaaggatgga atgaatttgt aggtcaaatt tttggtccag attgggctgt
    18601 aaaattgcaa caaccaactg tagcaacatt tgaagtaatg actctacttg cagttttagg
    18661 gattggatat tcttatgcaa agcaaataga tgtagaccca atagcatcag cagcagttgc
    18721 aatagttgcc ttttttataa taacaccatt tgtaatacca tatacaccag aaggaacaga
    18781 atcagtttac atggtaacag gtataccact aggttggatg ggttctaagg gaatgtttgt
    18841 aggtatgata acagcaataa cctctgtaaa attatttgct gcagttgtaa aaaaaggatg
    18901 gacattgaaa atgccagatg gagttcctcc aactgtatca aaatcatttg cagcattaat
    18961 accaagtgca atagttatgg tagttttctt tttagttaag atagcttttg aagctacacc
    19021 atatggaagt atacatgaat ttatatttaa gtttttacaa atgccattat taaaattagg
    19081 aaatagttta ggtgctatgg caatcgctta tatattctta catttattct ggttctttgg
    19141 aataaatgga agtagtgttg ttggggctgt gtataatcca atattaaaaa ttctatcagc
    19201 tgaaaactta gctgcttttc aagctggttc aaaaatacca aacataataa caggtcaatt
    19261 ccaagatatg tttgcgacat ttggtggagc aggtagtaca ctatcattag tcatagctat
    19321 gttattaata tgtaaaagta aacgtataaa gtcaatggga aaactatcaa ttttaccagg
    19381 aatatttggt ataaatgagc cattgatatt tggtctacca ataatgctta acccaatact
    19441 attgatacca tttgcaatag ttccaacaat aaatataata atagcttact tctgtatgtc
    19501 agcaggatta gtgcctctta caaatggagt tcagttaccg tggacaactc caattatatt
    19561 ctctggtttt ttaacaacag gatggcaagg tgcagtctta caattagtac ttcttatact
    19621 aggaatattt atgtatatac catttataaa aatgctagat aagcaatact tgagagaaga
    19681 aaatgaaact gttgaagagg aagatgatga tatatctttt gatgatttag tattatagga
    19741 ggaagattat gaagaaaata gttatgatat tggaccaaat acaagctgga gctggaggaa
    19801 aagagaaaag taatatacct cctgctggaa aatcaagccc attaggacca ggtgtaatga
    19861 tggagcaatt tttaaatgaa tctaaggtaa tagctacctt attttgtggg gatgaatttt
    19921 ttgtaaataa tcaagaagaa gtaacgagta agatgatagc tatggtaaaa aaattaaacc
    19981 ctgatgtagt aatctgtgga ccaagcttta attacgaaaa cttttctaag atgtcagcaa
    20041 tactgtctaa aaatataaat gataaaacag atataccagc ttttgcagct atgtcagaag
    20101 aaaatataga tgtgataaac gaatataaaa atgacatatg tatagttaag actccaaaaa
    20161 aaggtggaat tggtcttaat gattcattaa ataacatatg taaattggca aaagcaatag
    20221 caaataaaga agatataact ttgatgaaag aagagttttg ttatcaataa gagtattaat
    20281 tattagcaag tttaaatatt atactattta taataagcat acattagtaa aatctatata
    20341 atttaaggag gggaatttta acatgtgggg aatgatagcg acatggagaa tggccctaga
    20401 aggaataact gaggcatcag aacatttaga aaaaggcatg gaagcaggtg atgctgtaga
    20461 gcttgctgta agaagagttg aagactatcc attctataaa tcggttggat atggtggact
    20521 tccaaatgaa aattgtgagg tagaacttga cgctgcattt atggatggta acacattaga
    20581 tattggcgca gttgctggta taagagatta ttctaatcct gtcagcatag ctaggaagtt
    20641 aagttatgag aaggtaaata attttttagt tggaataggt gctgaagatt atgctcataa
    20701 aaatggattt gaaagaaaaa atatgttgac tgatagagcg aagttacatt ataaaaagag
    20761 aaaaaaagag actttagaca aaggattaag cccatatgct ggtcatgata ctgttggtat
    20821 gatatcttta gacaaaactg gaaaaatgtg tgcagctaca tcaacaagtg gattgtttat
    20881 gaagaaaaga ggtagaatag gagattctgc actatctggt tcaggattct atgttgatag
    20941 tagtatagga ggagctacag ctactggttt gggagaagat ttaatgaagg gatgtatatc
    21001 ttatgagata gttagactta tgaaagaagg gaagcatcca caagaagcat gtgatattgc
    21061 agtaaatgaa cttgataaac agcttatcaa aagaagggga aaagctggtg atttatcatt
    21121 agttgccatg aataataaag gtgaatgggg agtagctaca aatatagctg attttacttt
    21181 ttcagtagta actaaagaag aatctcctac tgtatatatt tcaaatagag tagatggaaa
    21241 gactatacat aaggttatat caaatgagtg gatggaagca tatgaggcta gaataaaagc
    21301 accaatagaa gtaagtgagt aaagtagtgg ttacataatt aaaatagagt tttataataa
    21361 ggagattttt atgaatatca taagtaataa aatagatgag ttaaaagaag atttattaag
    21421 tgatattata gatattgtaa aaatacctag tgtcaaaggg gagtcagaaa atggcttccc
    21481 ttttggcgaa aaagtagggg aggcacttaa taaagcatta gaaatatcag aaaaattggg
    21541 atttaaggtt agaaacttgg ataattatat tggttatgca gagcatggag atagtgatga
    21601 ttatgtttgt gtaattggac atgtagatgt tgtacatgaa ggagatggtt ggaagcatca
    21661 gccttataag ggagaagaaa ctaatggaag aatttatgga cgaggagtac tagacaataa
    21721 aggacctata atgtctgcct tatatggatt atatgctatt aaagaattaa acttaaaatt
    21781 agataagaga gttagaataa tatttggtac aaatgaagaa agtggatttg aagatatacc
    21841 atattattta gaaaaagaaa aagcacctat tatgggattt acaccagatt gtaagtatcc
    21901 tgttgtatat ggtgaaaaag gcatggcaaa gattagaata aaaagtaaaa tcaattatga
    21961 agaagatgta tacctaggtt ttatagaaaa tatgtctgaa aatgtgcttg ttacatataa
    22021 agagctgaat atagaaaata gtgatactat attagatata aaggtaaaat acgattttag
    22081 ttataaattg aaagatgtat tagatgaaat aaaagctagt tttccaaata gtatcgatat
    22141 agaggtaatt tctaatttta atcctgtata ttttgataaa gagagtaatc ttgttaaaaa
    22201 gcttcagcta gcttatgaaa gggttacatc attagatgga actccagtaa caactaatgg
    22261 aggtacgtat gcaaaagtaa tgccaaatat agttccgttt ggaccctcat ttccaggaca
    22321 aaaaggaata gctcataatc ctgatgaata catggatata gaagatataa tattaaatgc
    22381 aaagatattt gcaaatgcaa tatatgaatt agcaaaggag tagttatgtt agaaataata
    22441 ggaatgtcag tagaagacgc taaaattata gaagattgtg gtgcagatag aatagagtta
    22501 gttagtgctt taactgaagg tggattgaca ccaagttttg gtcttataga aagtgttgtt
    22561 aacagtgtaa agatacctgt gaacgtaatg ataagacatc atgcgaaaag ttttgtatac
    22621 agtaaagaag atataagtat aatgcaaaaa gatataggtg tggttaaaga gattggtgct
    22681 aatggagttg tatttggtgt attggataaa aacaatagta tagatgagaa aaatctaaat
    22741 gttttattga aatgttgtga taatcttgat gttacatttc atagagccat agatgaatca
    22801 aatacaatag atagtgttaa aattttgaag gattatgata aaattacgaa tatattaaca
    22861 tcaggaggga aaggaagtat agttgataac atacaaatga taaagaatat gatgcttagt
    22921 tctaatcaca taaaaattct tttaggtgga ggtcttaatt ttaataatat agaaaagata
    22981 aaggaattaa ctaaggcaag taattttcat tttggtacag cgattagaat aaataacagt
    23041 ccttttgaag atatagatag acaaaagctt aaacaactcg taaatataat ttcaagatag
    23101 tatatgaata taaaacactt agtttaaata aagagagtaa gttaattata atttgggtat
    23161 atgaatgtta ataggtatta aatatgaaat tattgttgag tatgctttat aacttttaag
    23221 tagttttaaa tataaataat gaaagaaaag atagattatg gaggttttag agggtttata
    23281 tttattaaaa aattataaag gtatattggc atataataca cataatttcc taaaattacc
    23341 atcttatgac atgaattcac atattaataa acaattaatg gagatttttg tggatagaaa
    23401 taggagtaaa aatagcttta aataaacaaa aacaagagtt attaacagtt ttatccacat
    23461 tatccacagg tgtttgtaat aatattaatc cacataagta tcaatgtaac taaaaatgat
    23521 aaataattct atcaattgaa tagaaaaaat cataaaagta aataataaaa agaggattat
    23581 gagagttcgt gtagaatata ttattaaagt ataaattttc ttatactggc ataattgaag
    23641 ggagatgtat ttatgaacat aattatatct ggaaaacaaa tcgaattaac tgatgcaata
    23701 aaaaataaaa tcgaaactaa actaagtaag ttagataatt acattcatcc agacactgat
    23761 gtaaaagtta cagtaagtgc gagaaaagca agacaaaaaa tagaagtaac aatagctact
    23821 gtaaatggtc ctataattag agcagaagat atgcaggaaa atttatacac agctatagat
    23881 gttgtatatg ataaattaag taaacaatta aaaaaatata aaaagagatt acaagataaa
    23941 cataaagaca acaagagtat aagattccaa gatgcagaga taaatctagc tgatgaacaa
    24001 gaggattatg gggatgaaaa tcaagaatta gtaattcaaa gacgtaagaa atttagtgtt
    24061 aagccaatga gtgaagaaga agctgtatta cagatggaat taataggaca tgatttttat
    24121 atgttcaaga acatagattc agatgaaata gcagtagttt ataagcgtaa taatggtgga
    24181 tatggtataa tagaacatga ataaagcaat ttagatttaa tcatattagc tatcgataaa
    24241 taaattatcg atagcttttt aaattaatat taaaagtata gtttttatgg taaaatgaat
    24301 aatagtacaa taaagaacga ggagagatgt aaaatatgag ctttatggat aatttattca
    24361 acatggcaga taaaaaagaa ttaaaaaagt tcaataaaac tgttgatata atagattcat
    24421 tagaacctaa atttgaatct atggcagact cggaacttaa aaatatgaca aatatattta
    24481 aagaaagatt agcaaatggt gaaagtatag atgatatact tccagaagct tttgcagtag
    24541 ttagagaagt ttctaagaga gtgttaggac ttagacacta cagagttcaa atgattggag
    24601 gtatagtact acatcaagga agaatagcag aaatgaaaac aggtgaaggt aaaactttgg
    24661 ttgcaactgc tcctgtttat ttgaatgcgc ttactggaaa aggtgtacat gttgtaacag
    24721 taaatgatta ccttgcaaaa cgtgatagag accaaatggc aaaaatctat gagtttttag
    24781 gaatgagtgt aggcgttatt atacacggtc aaaatccaaa agttagaaaa gaacaatatg
    24841 attgtgatat aacttatggt acaaataatg aatatggatt tgactatcta aaggacaata
    24901 tggtaataca caaagagcaa agagttcaaa gaggattaaa ttatgctata gtggatgagg
    24961 ttgactctat actaatagat gaggctagaa caccacttat catatctgga cctggagaca
    25021 aatcaactca cttatattca gatgcaaaca catttgtttt aaccttaaaa ccagatgatt
    25081 atgaattaga agaaaaagat aaggctgtat ctctaacagc atcgggtata caaaaagcag
    25141 aagtgtattt taatgttgat aatataacag atatatctca tacagaatta taccatcata
    25201 taaatcaagc tttaagagca catgtaataa tgaagaaaga tgttgattat gttgctaaag
    25261 atggagaaat agtaatagta gatgagttta caggtagact tatgtttggt agaagatatt
    25321 cagaaggttt acatcaagca atagaggcta aagaaggtct taaaatacaa agagaatcta
    25381 aaacactagc tactgtaaca ttccaaaact actttagaat gtacaaaaaa ctttctggta
    25441 tgactggtac agcaaaaaca gaagaagaag agtttaaagc aatctacaaa atggatgttt
    25501 tccaagtacc tactaataag cttatgataa gggaagattt accagattgt gtatacaaaa
    25561 gtgaaatagg taaatttaat gctgtagcac aagaaataat tgaaaggcac aaagtcaatc
    25621 aaccaatact tgtaggtaca gtatcaatag aaaaatcaga attattatca caaatactaa
    25681 agaaaaaggg cataaagcac gaggtattaa atgctaagca tcatgataaa gaggcagaaa
    25741 taatagcaca agctggtaga cttggagctg ttacaatagc tactaatatg gctggtcgtg
    25801 gtacagatat agttctaggt ggaaatccag actttttaac taagagagaa atgagaagaa
    25861 atggatttaa agaagaaata gtaaatagag tagatactcc aatagaaggt atacctgtaa
    25921 aaggtaatga aattctattt gaagctagag aagagtatga aaaactattt gaaaagttta
    25981 agcaacaaac acaagaagaa caaaaacaag ttgtagaagc aggtggactt gctataatcg
    26041 gtacagaaag acacgaatct cgaagaatag ataaccagtt gagaggtcgt gctggacgtc
    26101 aaggtgaccc agggagttca agattctata taggtcttga tgatgacctt atgagattgt
    26161 ttggtagtga tagaatatct ggtattgtag ataaaatagg tcttgaagaa gacatgccga
    26221 tagaacatag aatattatct aagtctattg aaggagcaca aaagaaagtc gaaggtaaaa
    26281 actttggaat aagaaagcat gtacttcaat atgatgatgt tatgaataaa caaagagaaa
    26341 taatatatgc agagagaaaa cgtgtattag aaggtgaaga tttacaagaa caaatacaat
    26401 caatgactca ttctataata gaagaagcag ttactcttta tacacaagat aaaggatttg
    26461 atgaagaagg attcaaagaa catatgtata atttgttctt gccaaaaggt agcatagaaa
    26521 taccagaaat agaaaaactt aatccagttg aaataacaga aaaagtttat gaaatagcta
    26581 tgaagatata tacttcaaaa gaagaacaag ttggctatga gagaatgaga gaagttgaga
    26641 gagtaatctt acttcaagct gttgataacc attggataga ccatatagat gctatggacc
    26701 aattacgcca aggtattggt cttcgtgctg taggtcagca agacccagtt attgcttata
    26761 aaatggaagg ttttgatatg tttgatgaaa tgaataaaca tatcaaagaa gatactgtaa
    26821 gatatttatt taatataaca atagaaactc cagtggaaag aaaagcagtt gtagatgttg
    26881 aaaatctatc ttctccatca gatggaacac ttccaacaag taaaactgtt aaaaaagatg
    26941 aaaaggttgg aagaaatgac ttatgccctt gtggaagtgg taaaaaatat aaaaactgtt
    27001 gtggaagata atctcggagg attaaatgtt aaagttacaa gagtatagac atagtatgga
    27061 gcagatggct tcaaatttag aagaattgag ggtttctctt tgacatagct tcattgatga
    27121 aaaatataca aattaatgaa gaaaagatga atcaacaaga cttttggaat gataatgaag
    27181 tcgctcaaag agtacttcaa gaaaataaat ctttaaaaga gacattagaa gaatatgaaa
    27241 gcttaaaaag cttattagaa gatatagaag tattaattga aataggttta gaagaagatg
    27301 atgattctgt agaaagagat atagaaaagt ccatagaatc aatggaagaa aaattatctg
    27361 aaatgaaaat aaagactctt ctaaatggag agtatgataa aaataatgct atattatcta
    27421 taaatgctgg tactggtggc ttagatgctc aagattgggc tcaaatgctt ttgagaatgt
    27481 atataagatg gtcagaaagt aagggttata aagttaagct tttagatata atatcagacc
    27541 ctgaagcagg gataaagaca gctacaattc ttgtagaagg aacaaatgct tatgggtatt
    27601 taaagagtga aaaaggagtt catagattag tgagaatatc tccatttgac ccatcaggaa
    27661 aaagacatac ttcatttgca tctatagatg taacaccaga gttagatgaa aatatagaag
    27721 tagaaattaa tccatcagat ttaaagatag acacatatag agcttctgga gctggagggc
    27781 aacatgtaaa tacgactgat tcagcagtta gaataacaca tatccctact ggtgtagtag
    27841 ttcagtgcca aaatgaaagg tctcagcatc taaataagga cagagctatg agacttttaa
    27901 tggcgaaatt gatagaatta aaagagttag aacaaaagga aaaaatagaa gatatacaag
    27961 gcaaatactc acaaataact tggggtagtc aaattaggtc atatgttttt caaccatata
    28021 aattggttaa ggaccataga acaaatgctg agtttggaaa tgtagatagt gtaatgaatg
    28081 gaaatataga cttgtttatt aatgaatact taaaaatgaa taaaatagtt taataaatat
    28141 gcactgtaat taagatatat gtataagaag gttagtgctt aatatgcact tacagcactt
    28201 aggctgagga cgataaccct cagccttcgt tctgttttgt tatacttatg aaaaactaac
    28261 attaggagtg aataaattgg atataaatca aatcttaaaa aaagagttta atcttagaga
    28321 tgaacaaata aataatacat taaaacttat tgatgaagga aatacaatac catttatagc
    28381 tagatataga aaagaaatga ctggcgaaat gagtgatgtt acactaagag aattttatga
    28441 aaaattaatg tatttgagaa atcttcaaag tagaaaagat gatgtagtta gactaataga
    28501 tgaacaaggg aaattaacag atgaaataac acaaaatata gaaaaagcaa aaacattaca
    28561 agaagtagaa gatatatatg ctccatataa acaaaagaaa agaactagag caacaatagc
    28621 aaaagaaaaa ggattagaaa atttagcatt gtcaatacta gagaataatt tagataatat
    28681 agaaatagag gcaaagaatt atcttgatga agagaaagaa gttctttcta ttgaagatgc
    28741 tctaaaaggt gctagagata taattgcaga actagtctca gatgatgcta agattagaaa
    28801 gtatataaga gaattagctt taagagaagg tatgatagtt agcaaaagtg ctactgatga
    28861 gaaatcggtt tatgatatgt attatgatta tagcgaagca gtaaaaagta tggctccaca
    28921 tagagttttg gcaataaaca gaggagaaaa agaaagtttc ctaaaggtta agttggaaat
    28981 aaataatgat aaagttttaa attacataat aaacgaatat gtaaatgata aaaatttcaa
    29041 aaataaagaa gaaatcgtaa gttcaataga agattcttat aaaagattaa ttttcccatc
    29101 aatagaaaga gaaataagaa atcatttaac agaaatagct caagaaagag ctataagtgt
    29161 atttggaaag aatgttaaaa gtttattgct tcaaccacca gttaaagaca aagtagttat
    29221 gggatttgac cctgcattta gaactggatg taaaatagct gtagtagata aaaatggtaa
    29281 actactagat tatacaacag tatatccaac agaccctcaa aatgatgtag agggagcaaa
    29341 gaaagtttta aaaggattga ttgaaaaata cgatatagat ataatttcaa ttggaaatgg
    29401 tactgcatct agagaatcag aaacttttgt atcagaaatg ataaaagaaa tagataacga
    29461 agtgcagtat gtgatagtta gtgaagcagg agcatctgtt tattcagcct ctgaacttgc
    29521 aaatgaggaa catccagata taaatgtatc aataagagga gctatatcta tagctagaag
    29581 attacaagac ccattagcag agcttgtaaa aatagaccct aaaagtattg gcgttggtca
    29641 atatcagcat gatttaaaca aaaagagatt agaagaagta ctagatggag ttgttgaaga
    29701 ttctgtaaat agtgttggag tagatttaaa tactgcatca tactccctac tagaacatgt
    29761 tgcaggaata agtaaaacta tagcaaaaaa tataatagca tatagagaag aaaatggaga
    29821 ttttacgtca agagcacaat tgaaaaaagt aaagagacta ggaccacaag catttactca
    29881 atgtgctgga tttatgagaa tcttagaggg taaaaatcca ctagataata caggtgtgca
    29941 tcctgaaagt tatgatatat gtaaaaaaat gattgagata attggatatt ctttagatga
    30001 tgtaaagaat aagaatatat gtgaaataga tgaaaaaata aaagaaattg gcttgagaga
    30061 attaagtgaa aaactggaag tagggcaagt tacgttaaaa gatatcataa ctgaaatcaa
    30121 aaaaccagga agagacccaa gagaagaagg tataaaacct atacttagaa ctgatgtctt
    30181 aaaaattgaa gatatacaag agggtatgac tttaaaaggt acaataagaa atgttgtaga
    30241 ttttggtgca tttgtagata ttggaataaa aaatgacgga ttagttcata aatcagaaat
    30301 gagtaatagt tttgtgaaag accctatgag tattgttaca gtaggtgata tagtagatgt
    30361 aaaagtcatt ggaattgact taaacaaaaa aagagttgcc ttatcaatga aaaaatagat
    30421 aagtttatgt atggttatag tacttaaatt ctatgtttgt aaatgaggtt actcgagtgt
    30481 ataaatgtta aaaatttgta aaagtataca gtaagaaaat atattaaaat aagaacgata
    30541 gtcttgaaaa tcaggaggaa aatgaatgat ttttataaaa aatggtaaaa taaataccat
    30601 aacaaatggg ataattcatg gagatatact tatagatgaa ggaaaaataa tagaaattgg
    30661 agaagatttg atagctcctt tagatgtaga ggtaatagat gctagtaata aacttgtgtt
    30721 tcctggattt atagatgctc atactcattt aggtttgtgg gaagatggta tagggtttga
    30781 aggagcagat ggaaatgaag agactgaccc aataacacca caattaaatc ccatagatgg
    30841 aattaatcca atggatagaa cttttaaaga agcttttgaa ggtggaataa cttctgtttg
    30901 tacaacccct ggaagtgcaa atgttatggg tggtcaatgt atagctataa agacatgtgg
    30961 aaaaagaatt gataaaatgg taataaaaaa tccagttgca tctaaaatcg cttttggaga
    31021 aaatccaaag agctgttatg gtcaggatga taaatctcct caaactagaa tggctatagc
    31081 tgctttactt agagaaaacc taaaaaaagc agaagaatat ttagaggata ttgatatgta
    31141 tgagagtcat gatgatgaag actgtgaaaa acctgaatat gatataaaaa tggaaagttt
    31201 aataccagtt ttaagaagag aaattccttt taaggcacat gctcatagag cagatgatat
    31261 gtttacagca ataagaattg caaaagaatt taatttaaag cttacattag accattgtac
    31321 agaaggtcat cttattgtag atgaattagt ggaagaaggg tttcctgtaa tagtagggcc
    31381 atctttgtca gaaaggtcta aatttgagct tagaaatttg acatttaata cagcaggaat
    31441 actttcaaat gcaggtcttg atgtatgtat aatgacagac catccagtaa taccagttca
    31501 atatcttcca atatgtgcag gtattgcagt caaacatggt atgaaagaag aaaaagcaat
    31561 agaatcaatt acgataaatc cagctaagac tttaggaata gaagatagag taggctctat
    31621 agaagttggt aaagatgcag acctagtaat ttgggataat tctccactag agattcaaag
    31681 taatgtactt tacactataa taaatggcaa agtagtgtat gagaaaaaat aacttgacaa
    31741 ttattaaaaa attaactaat ataagagtgt aaggaaaatt aaaaaatcaa agaagatctt
    31801 cggggcaggg cgaaattccc taccggcggt atagcccgcg aactacttaa gtggttgatt
    31861 tggtgagatt ccaaagccga cagtaaagtc tggatgagag aagatattta tggaagataa
    31921 ataagtttat tttagtttgt ttaaactata tccataaaaa ctcgaagata gggtcttcga
    31981 gttttttgtt tttcctaaaa aatataaaca tattgattag ggggaaataa ttatgcaaaa
    32041 cacagccaaa agaggcaata tgatttcaac aagaacttta gtagtaatgt caattttatc
    32101 tgcaatatct tatttattaa tgtttattca agcaccaata ccaggtatat ttccagattt
    32161 cttaaaaatt gacttatcag atattccagc aatattcgga ggaatgtctc taggaccatt
    32221 tgttggattt ggaatagttg tagtaaaaaa tgtgttacaa gcaataacag caacaacaac
    32281 tggaggaata ggagaatttg caaatatatt aattggtggt tcttatgtaa tgatactttg
    32341 ttattcatat aagagaagtg gagatttaaa aggtgtattg attggttttg tattaggaac
    32401 aatatctatg actataattg gttcattagt aaattatttt gtaatgttgc cactttatgg
    32461 tcaacttatg ggactagatg ctataatagg tttaggttca gctataaatc ctcaagttca
    32521 tgatttattc acttttgtaa tttggatgat agctccattt aatgtgctga aggctgttat
    32581 aatatcttta gtaacattgc cactttataa aaaaatggga aatataataa agaaataatt
    32641 agacaagaaa atataaaatt aaatgcattg aatagccata atttatttat aacttcagtc
    32701 ctatattgtg attgatatat taaatatatt atggctttat taatttatca aaaaatgtat
    32761 ataaaataag aaatatttag acaaatttaa attttaaaat aaaggaagaa ttaaaacgat
    32821 taactattaa aatatgaaaa aggtatctac aatatacaga gcgaatttat aataaacaaa
    32881 aaataaagtt attattaaaa aactataaag attaataatc aaacttttaa taataactaa
    32941 tttaataatg ataggggtgt atattcatgc atttatctaa aaaaataaaa aaattatttt
    33001 tagatgataa agggtattat tttaatagta attggaaaga tattcatatt ggtatttatg
    33061 atacaaaatt aggagattct ttaaagtata tcactaatga atatattgaa aatatggaaa
    33121 gtgtaaaata cgattatcgt gaattaaaaa atatagaaaa tcaaactgat ggtatgtgta
    33181 ttttagcaat aaggcagaat tacaaggcat tagagtatgt aaaaaatcaa accgaagaat
    33241 tatgtttaga agcaataaag tataattata aagcacttga atatgtaaaa gaacaaacag
    33301 aatacttgtg tcttgaagct ataaaaaaag attgtaatgc acttaagtat gtacgaaata
    33361 aaacagaagg gcttattata aaagcaataa gtcattcttc caatatagat gttgtaagta
    33421 tactaaaggc tttagagact caaacaagaa ggatatgttt agaagcaatt aaaaaagatg
    33481 gcaggtgtct tgcatacgtt agagaacaga gtgaagaatt atgtatagag gccattaagc
    33541 aaaattataa agcattaaaa tatgtaaaaa atcaaacgga aaaaatgtgt atagaatccg
    33601 taagacaaaa tggtatggca ttacaatatg taaataaaca aactgataaa atatgtatag
    33661 aagctgtcaa acaagatgga agaagtatac aatttgtcaa caataagaca gaagaaatat
    33721 gtataaatgc tataagatat ttaaataaaa aatataatat taaagatgta ctaagttaca
    33781 tagataagta tacagaagat atatgtatag agattgtaag acaaaatgga aaaatgctta
    33841 tgtatataaa aaatcaaaca gaaaaaatgt gtattgaagc agtaaaagag aactataagt
    33901 ctcttaagta tgtaaaagag caatctgaga gaatatgtaa agaagcattg aagcaaaacc
    33961 ataaagcaaa agagtatgta aaaattgcta ttgatgattg tatataaggt gtagatacag
    34021 ccatcaatag tgaaagataa aaaaagataa agacaagtac tttataataa tctaggctta
    34081 tactataatt aattaagcag tgatataaat tcacatgacg attatatcaa aatggagatg
    34141 aattgatggc aaaaatatat ttagaaaatg aaaataaaac tagagaaata ggatataaat
    34201 taggtaaact tttaaaagaa ggcagtgtta tctgtttagt aggagattta ggagctggta
    34261 aaactacaat gacacaaagt ttggcagatt cattagggat agaagattat ataacaagtc
    34321 ctacttttac tataataaat gaatatgaag gaaaaatacc tttgtatcat tttgatgttt
    34381 atagaatagg tagtagtgac gaaatgtatg atattggtta tgatgaatat gtaaattcaa
    34441 atggaatctg tataatagaa tgggctaatc taatagaaga tatacttcca aaagaatatt
    34501 tgaatataga attgagatat aaagatgaag gaagagaaat gatattaact ccaaaaggag
    34561 agttttataa agagatagtt gaggagttga ttaaataatg aaaatactag gtatggatac
    34621 gtcttctatg gcagcaagtg tagcagttgt tgaagatgat aacttaatat gtgagtttac
    34681 agtaaacaac aaaataactc attcacaaaa gcttatgcca atgatagaaa atatgttgag
    34741 tatgagtgat ttaagtataa aagatatgga tttattagct gtatgtatag gtccaggttc
    34801 gtttacagga cttagaatag gtatggctac agtaaaagct atggcccatg taaataatat
    34861 accaataata gcagtaaatt ctttggaatc tctagcaaat aacataaatt tctgtgatag
    34921 aaagatatgt tgtatattag atgcgcagaa aaatcaagtt tattcagcta aatacaagtt
    34981 tgaaaatgga gagatgatag aattagatgg tgttgatgtt gtagattttg atgctttagt
    35041 agatgaaatt gtatcaacta atgaagaatt tataatagtt ggagaagctg tatacaaata
    35101 taaagacaag ttagagaata taaaaaatat aaaaatacct tcaccagcta ataatgtatc
    35161 taacgcagga agcttatgct ctttagcatt aaataaatat aataaaaata tagatgtaca
    35221 tacttgttat acgataaatc ctatgtatat cagaaaatct caagctgaag tacaatatga
    35281 tgaaaaaatg aagaggctaa ataatggaag ataatacaaa actaatagta gatgatataa
    35341 aaatagaaga aatgactaca gaagatatag atgaagtttt tgaagtagaa aaaaattgtt
    35401 ttgaagatta ttggtcaaaa gagtctttta gaaaagagtt gtctaatgaa gtagcaaggt
    35461 atatagtagc taagttaaat ggaaaaattg tcggatatgt gggaatttgg cttatacttg
    35521 atgaagggca tataaataat gtggctgttc atagtgacta tagagggaaa aaaatagggg
    35581 acaagttgat aaaaggcata gttgatttat gtaaagataa taatattgca tctatgacat
    35641 tagaagttag agcatcaaat aaaatagcac aaaatttata tagaaaatat ggatttaaaa
    35701 tgggtggaat aagaaaagaa tactacagtg ataataaaga agatgcaatt ataatgtgga
    35761 accaattaaa agaggtgtag agtttatgag tgatataata acattagcta tagagagtag
    35821 ttgtgacgaa acagctgcat cagttttaaa aaatggtaga gaaatacttt caaacataat
    35881 ctctactcaa atcgagacac ataaaaaatt tggtggtgta gttccagaag tggcctcaag
    35941 aaaacatgtg gaaaatattg atatagttgt tcaagaagct ttagacaaag caaatatagg
    36001 ttttaatgat atagaccata tcgcagttac atatggacct gggctagtag gtgctttatt
    36061 ggttggtcta tcttatgcta aagcacttgc atatactttg aatattccac ttgtaggagt
    36121 aaatcatata gaagggcatc taagtgcaaa ctatatagag cataaggatt taaaacctcc
    36181 ttttataaca ttaatagtat ctggaggtca tactcacttg gttgaagtaa aagattatgg
    36241 caagtatgaa attttaggaa aaacaagaga tgatgcatct ggagaagcat ttgataagat
    36301 ttcaagagct atgaatttag gctatccagg aggtcctatt attgataatc tggccaagaa
    36361 tggaaataaa catgctatag aatttccaag agcctattta gaagaagata gctatgattt
    36421 tagttttagt ggattaaaat cttctgtatt aaattatcta aatggaaaaa gaatgaaaaa
    36481 tgaagaaata gtagttgaag atgtagcagc atctttccaa gaggctgtag tagaggtttt
    36541 atctactaaa gcactaaaag cagtaaaaga caaaggatac aatatcataa ctctttctgg
    36601 tggggttgct tctaattcgg ggcttagagc taaaataaca gagcttgcta aagacaatgg
    36661 tattactgtt aagtatcctc ctctaatttt atgcacagat aatgcagcta tgatagggtg
    36721 tgcaggatat tataatttta taaatgggaa aacgcatgat atgagtttaa atgcagttcc
    36781 aaatttaaag ataaatcagt agagttagat gaatttgtaa atataaaagt attgtttcaa
    36841 aaaagtaagt agaagtgaaa ttaaatataa taaaaataaa tatagtatat attaaaactt
    36901 gaagtaaaac tatttataat ctttatattc caatgaattg caacaaattt taggatatac
    36961 agattgtctt tggcttagat ttgcttcaag tttatttttt tctatagaaa gattatttta
    37021 aaaagtgggt aatataccct tttttttcat tcttaaaaag ttttatacta attatagaaa
    37081 gattaaggag gggaagaaat gagtcaaagt aaagaagaca aaataagaag tattttggaa
    37141 gcaaaaaata ttaaatcaaa ttttcaaaat aaagaaaatt taagtgaatt taatgaaaaa
    37201 aaagcaagta aaagagcaga agacttatta gatgtatatt ataatacatt atctactgct
    37261 gatatggaat ttccatattg gtataataga gaatatagaa aatcagatgg tgatatacca
    37321 gtagttagaa gagctaaagc tcttaaagct gctttttcac atatgacacc aaatataata
    37381 cctggtgaga aaatagtaat gcaaaagaca cgccattata gaggttcttt tccaatgcca
    37441 tgggtaagtg aaagcttctt tgttgctcaa ggagaacaaa tgagagaaga ggcaaagaaa
    37501 ttagccagta acacagctga tgaacttaca aaatttgggt ctggtggagg aaatgttact
    37561 gaaagttttg gaaatgtcgt ttcaatagct ggtaaattcg gaatgagaaa agaagaagta
    37621 cctgtacttg taaaaatggc aaaggaatgg gttggaaagt ctgttgaaga tttaggtttt
    37681 cactatgaaa aaatgatgcc agattatgat ttaaaagaaa acctaatgag tacacttata
    37741 tgcatgtttg attcagggta tacacttcct caaggtagag aagttataaa ttatttttat
    37801 cctttaaatt atggattaga tggaattata gaaatggcaa aagaatgtaa aaaggcagtt
    37861 gcaggaaatg catctggaga tgggcttatt ggtatggacc gtctatattt ttatgaggct
    37921 gttattcaag ttattgaagg attacaaact tggattttaa attatgcaaa acatgcaaaa
    37981 tatttagaaa gtatagagac agatttagaa gctaaaaaag aatactcaga tttagtggag
    38041 atattagaac atattgcaca taaacaacct cgtacattta gggaagctct tcagttgact
    38101 tatacaattc atatagcatc agtaaatgag gatgctatat ctggtatgtc tataggacgt
    38161 tttggtcaaa ttttatatcc ttggtatgaa caagatatag aaaaaggact aattacaaaa
    38221 gaagaggtta tcgaattatt agagctttat agaataaaaa tcacttgtat tgactgtttt
    38281 gcttcagcgg gcgtaaatgg aggagtacta tcaggcaata catttaatac tttatctata
    38341 ggtggattaa aagaagatgg ttctacagga gctaatgaac tagaagagtt attattagaa
    38401 gcaagtatga gatgtagaac tcctcaacct agtttaacta tgctatatga tgaaaagctt
    38461 ccagaagatt tcttaatgaa agctgctgaa tgtacaaagc ttggttctgg ttatccagca
    38521 tgggtaaaca actcaaatgg aacaacattt atgatgaaac aatttgctga tgaaggtatg
    38581 actgttgaag aagcaagagc atttgcatta ggtggatgtt tggaaacgtc tccagggtgt
    38641 tggaaacagt taactttaaa cggaaaaaca tactctattg caggtggagc aggtcaatct
    38701 gctggctctg gagttcactt tatagctaat ccaaaaattt tagaacttgt tcttatgaat
    38761 ggtaaagact atcgtatgaa tatacaagta tttgagcctc ataataagcc attagatact
    38821 tatgaagaag tcatagaagt atttaaagat tattataaac aagcaataaa tgttttagaa
    38881 agagcaaata acattgagtt agatatatgg agaaaatttg atacttctat aataaattca
    38941 ctactaaagc cagactgttt agacaaaggt caacatatag gaaatatggg atatcgttat
    39001 aatgcaacat taaacgtaga aacttgtggt actgttacta tggtcaattc atttgcagca
    39061 cttaagaaac ttgtatatga tgacaaagca tttacaatag aggaaatgaa ggatgccata
    39121 ttaaataatt ttggatttaa agatgcatta gaagtaggaa attattctat ggcagaccaa
    39181 gtaaaagtag ataagactgg taaatatgat gctatttata aggcctgtct tgatgcacct
    39241 aaatatggaa ataatgattt gtatgcagat aatattctta aaaactatga ggtatggtta
    39301 tcaaaagtat gtgaagaagc acaatcttta tatgctaaga agatgtaccc ttgccaaata
    39361 tctgtttcta cacatgggcc acagggagct gctaccttgg ctactccaga tggtagacta
    39421 agtggaacaa catattcaga tggttcagtc tctgcatatg caggaacaga taaaaatgga
    39481 gtatatgcat tatttgaatc tgcaactatt tgggaccaag cagtagttca aaattctcag
    39541 atgaatttaa aacttcatcc aactactata aaaggacaac aaggaactaa aaaattatta
    39601 gatttaacaa gaagttattt aagaaaaggt gggttccata ttcaatataa tgttgtagat
    39661 tcagaaacat taaaagatgc acaaaaaaat cctgacaatt atcgtcaatt aatggtacgt
    39721 gttgctgggt ttactcaata ttggtgtgaa ttaggtaaac caatacaaga tgaagtaatt
    39781 gctagaacag agtatgaagg ggtgtaaaat atgagaaagc atagtgattg tatgaatttt
    39841 tgtgcagtag atgcaaccaa aggaatttgt agattatcaa aacaaatgat taatttagat
    39901 gatgcagcat gtccagagat aaaagtaatg ccaaaatgta aaaattgtaa aaattttgtt
    39961 gaagctaatg atgaaggtat aggcaaatgt gttggcctag agaaagaaga ctgggtatat
    40021 tcaacattga atgcaattac ttgtgaagga catgtgttta atgagtagtc aaaagcaatt
    40081 agaaggcatg atttttgatg tacaaagctt ttcagttcat gatggtccag gttgtagaac
    40141 aactgtattt ttaaatggat gtccactgag ttgtaaatgg tgtgcaaatc cagaaagttg
    40201 gactgtaaga ccacatatga tgtttagtga attatcttgt caatatgaaa atggatgtac
    40261 tgtatgtcat ggtaagtgta aaaatggtgc attgagcttt aatcttgata ataagccagt
    40321 tatagattgg aacatctgta aggactgtga aagttttgaa tgcgtcaact catgttatta
    40381 taatgcgttt aaattatgtg caaaacctta cactgtagat gaacttgtgc aggtaattaa
    40441 acgtgattct aacaattgga gaagtaatgg aggagtaaca tttagtggag gtgagccact
    40501 acttcagcat gaatttttac atgaagtatt attaaagtgt catgaggtaa atatacacac
    40561 tgccattgaa acgagtgcat gtgtatcaaa tgaagttttt aataaaatat ttaacgatat
    40621 tgattttgca tttattgata taaagcatat ggatagagaa aaacacaaag aacaaacagg
    40681 tgtgtataat gatttaatat tagaaaatat atcaaacctt gcaaattctg attggaatgg
    40741 aagattagta cttagagtac cagttatctc tgggtttaat gatagtgttg aaaatataag
    40801 tgatattata tcttttatgc acaaaaataa tttggtagaa attaatctat taccatttca
    40861 cagattagga gaatcaaaat ggattcaatt aggcaaggaa tatgagtatt ctgataaggg
    40921 tgatgttgat gaaggtcatc ttgaagaatt acaagatata tttttggata atggtatagc
    40981 ttgttatgtt ggtcatgaga cagctttcta aaattaaata caagttttaa ttaaaaaaag
    41041 gatgttacac taaaagctag agttacatcc ttttttatgt ggtttttatg tagaaataat
    41101 taagtaaagt tttatatgtt ttatatattg tttatattgc tttatgtcca taaatattgc
    41161 tttaaatata ctttatatat tttttatagt ttaaattaca gttagagaat atattacgct
    41221 tacttcattg aagcagaagt tttgtggtaa aatactacta tgaaaaaatt taatagaata
    41281 tattttagaa acaactaaaa ataatagtta ggaggaagac atctatatga acaaatcatg
    41341 gagcaacttg attattaaga ataaagacaa aaaagtacgt tcagggtgga ttattatagc
    41401 tgttatggct accttttaca tacttcagta ttatttaagc atgatacttg tggaaataat
    41461 aagaaaaatc ctggttgcta caggtgacat taatttaaaa acaaactatt tttcagaata
    41521 tgctaattgg ttaaatgatg ttgggttaca gattgtattt caaattctaa cagattcact
    41581 tatgattatt attcctataa ttgtatggag atttattatg aaaaatccta ttagtgaaat
    41641 gggattacat tcttatagaa ttaagaaaaa agaaggatat gtaggaatgt tattaggaat
    41701 atttaattgt acagtaatct ttattataac aataacaatt ggtggtggtc atgttacttc
    41761 atgggtacca aaaatttcac ctttaacagt ttcttggata cttgtcttta ttttagttgc
    41821 ttttgcagaa gaaattttaa atcgtggttt ttttatggca gttttacgaa gatgtaaaaa
    41881 tatttatttt ataatgattg ttccatctgt tatttttggg ttgattcata tatggaatcc
    41941 tgatgttact tttttatctg taattaatat tataattatt gggattcttt tttcatatat
    42001 gtttataaaa tcgtcgaata tatggatgtg tataggttat cattttacat ggaatgtatt
    42061 tcaggggatt atatatggta tgcctgtaag tggacttcag gttccaggga ttataactac
    42121 acaaatcact catggtaatc tattaaatgg tggtatgttt ggtattgaag gtggaatttt
    42181 gactactttt gttaatctac ttagttttat atttgtatgg tattactata gagattctaa
    42241 gtatgatttt gttagtgata aagtaaatgt gaccaatatc aagaattagt tgattataat
    42301 aaattttaat aatatcttct aagcttaaag tattctgtag gattgttgga aatttacaaa
    42361 aatataaaaa taacttggat attctattta ctccaagtta tttttatatt cttttgtaaa
    42421 tagaaatgga acataaaaaa ttaaaacaac catagatact attagtatat catggtaagt
    42481 gatagttgat tctttagaat ttgtgataag aaaagcacta ttatttaaaa tatgaattat
    42541 agcacaaaac cagatgttct tagtttttat ataaagatat cctaaaaata ttgaaattcc
    42601 aactatatgt atcgaacgta atattaatcc taatattgg
//
LOCUS       DAGQVA010000029        42066 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.029, whole genome shotgun sequence.
ACCESSION   DAGQVA010000029 DAGQVA010000000
VERSION     DAGQVA010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42066
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.029"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            14..1870
                     /locus_tag="MIV85_001720"
     CDS             14..1870
                     /locus_tag="MIV85_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBY2961061.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    1953..2193
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    2259..2494
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2578..3795
                     /locus_tag="MIV85_001721"
     CDS             2578..3795
                     /locus_tag="MIV85_001721"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBY2961062.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNTKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            3912..4406
                     /gene="cdeM"
                     /locus_tag="MIV85_001722"
     CDS             3912..4406
                     /gene="cdeM"
                     /locus_tag="MIV85_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBY2961063.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGENRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            4671..5936
                     /gene="hisD"
                     /locus_tag="MIV85_001723"
     CDS             4671..5936
                     /gene="hisD"
                     /locus_tag="MIV85_001723"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBY2961064.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(6139..6891)
                     /locus_tag="MIV85_001724"
     CDS             complement(6139..6891)
                     /locus_tag="MIV85_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2961065.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(7009..7278)
                     /locus_tag="MIV85_001725"
     CDS             complement(7009..7278)
                     /locus_tag="MIV85_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961066.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            7753..8847
                     /locus_tag="MIV85_001726"
     CDS             7753..8847
                     /locus_tag="MIV85_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBY2961067.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISNITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            8849..9799
                     /locus_tag="MIV85_001727"
     CDS             8849..9799
                     /locus_tag="MIV85_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBY2961068.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKVDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            9792..10976
                     /locus_tag="MIV85_001728"
     CDS             9792..10976
                     /locus_tag="MIV85_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961069.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            10989..12485
                     /locus_tag="MIV85_001729"
     CDS             10989..12485
                     /locus_tag="MIV85_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBY2961070.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEECMKICEDFDFNIDPHMVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVND
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            12508..13458
                     /locus_tag="MIV85_001730"
     CDS             12508..13458
                     /locus_tag="MIV85_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961071.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            13479..14441
                     /locus_tag="MIV85_001731"
     CDS             13479..14441
                     /locus_tag="MIV85_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBY2961072.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            14813..15445
                     /locus_tag="MIV85_001732"
     CDS             14813..15445
                     /locus_tag="MIV85_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBY2961073.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            15856..15948
                     /gene="kdpF"
                     /locus_tag="MIV85_001733"
     CDS             15856..15948
                     /gene="kdpF"
                     /locus_tag="MIV85_001733"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBY2961074.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            15989..17671
                     /gene="kdpA"
                     /locus_tag="MIV85_001734"
     CDS             15989..17671
                     /gene="kdpA"
                     /locus_tag="MIV85_001734"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBY2961075.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            17696..19753
                     /gene="kdpB"
                     /locus_tag="MIV85_001735"
     CDS             17696..19753
                     /gene="kdpB"
                     /locus_tag="MIV85_001735"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBY2961076.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            19772..20398
                     /locus_tag="MIV85_001736"
     CDS             19772..20398
                     /locus_tag="MIV85_001736"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBY2961077.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEQFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVEDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            20635..21543
                     /gene="cysK"
                     /locus_tag="MIV85_001737"
     CDS             20635..21543
                     /gene="cysK"
                     /locus_tag="MIV85_001737"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBY2961078.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            21570..22160
                     /gene="cysE"
                     /locus_tag="MIV85_001738"
     CDS             21570..22160
                     /gene="cysE"
                     /locus_tag="MIV85_001738"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBY2961079.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            22320..22508
                     /locus_tag="MIV85_001739"
     CDS             22320..22508
                     /locus_tag="MIV85_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBY2961080.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(22562..23431)
                     /locus_tag="MIV85_001740"
     CDS             complement(22562..23431)
                     /locus_tag="MIV85_001740"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBY2961081.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDVINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(23628..24872)
                     /locus_tag="MIV85_001741"
     CDS             complement(23628..24872)
                     /locus_tag="MIV85_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961082.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYNMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            25163..25474
                     /locus_tag="MIV85_001742"
     CDS             25163..25474
                     /locus_tag="MIV85_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBY2961083.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      25567..25659
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            25759..26553
                     /gene="thiD"
                     /locus_tag="MIV85_001743"
     CDS             25759..26553
                     /gene="thiD"
                     /locus_tag="MIV85_001743"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBY2961084.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            26577..27365
                     /gene="thiM"
                     /locus_tag="MIV85_001744"
     CDS             26577..27365
                     /gene="thiM"
                     /locus_tag="MIV85_001744"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBY2961085.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            27388..28020
                     /gene="thiE"
                     /locus_tag="MIV85_001745"
     CDS             27388..28020
                     /gene="thiE"
                     /locus_tag="MIV85_001745"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBY2961086.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKQYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            28159..28461
                     /locus_tag="MIV85_001746"
     CDS             28159..28461
                     /locus_tag="MIV85_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2961087.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(28527..29276)
                     /locus_tag="MIV85_001747"
     CDS             complement(28527..29276)
                     /locus_tag="MIV85_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961088.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(29270..30232)
                     /locus_tag="MIV85_001748"
     CDS             complement(29270..30232)
                     /locus_tag="MIV85_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961089.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNALSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDAIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(30236..30694)
                     /locus_tag="MIV85_001749"
     CDS             complement(30236..30694)
                     /locus_tag="MIV85_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBY2961090.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNFPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            31049..31405
                     /locus_tag="MIV85_001750"
     CDS             31049..31405
                     /locus_tag="MIV85_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2961091.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            31477..32193
                     /locus_tag="MIV85_001751"
     CDS             31477..32193
                     /locus_tag="MIV85_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961092.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            32186..33010
                     /locus_tag="MIV85_001752"
     CDS             32186..33010
                     /locus_tag="MIV85_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961093.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYSLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            33022..34221
                     /locus_tag="MIV85_001753"
     CDS             33022..34221
                     /locus_tag="MIV85_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961094.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIETIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            34230..35042
                     /locus_tag="MIV85_001754"
     CDS             34230..35042
                     /locus_tag="MIV85_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961095.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVKVTGFSSFRNIMGSTESWFMFGIIACICYSFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            35053..36321
                     /locus_tag="MIV85_001755"
     CDS             35053..36321
                     /locus_tag="MIV85_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961096.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            36687..37868
                     /locus_tag="MIV85_001756"
     CDS             36687..37868
                     /locus_tag="MIV85_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBY2961097.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(38010..38927)
                     /locus_tag="MIV85_001757"
     CDS             complement(38010..38927)
                     /locus_tag="MIV85_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961098.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            39180..39974
                     /locus_tag="MIV85_001758"
     CDS             39180..39974
                     /locus_tag="MIV85_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961099.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            39975..42035
                     /locus_tag="MIV85_001759"
     CDS             39975..42035
                     /locus_tag="MIV85_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBY2961100.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT        16337 a         4505 c         7251 g        13973 t
ORIGIN      
        1 tagtggttag aatatggata cccataataa atatgtaaat tttataaaaa atatacctgt
       61 acctttttta tattgtagaa ttgtaaagag acaagaagat atagaatatc gagtagaata
      121 tataagtaag ggtatgggca aagtattaca attagaagaa ggtatttgtg ataaaaatat
      181 actagatgta ttgcctgtat ttaagtctaa aaaatatttc aaagagttgt tctcaaatga
      241 agtggattgt ataaaaaggt acattccgac acttaaaaac tggataaata taaaaaaaca
      301 gataataggg gattcataca taattttgta ttttggtaaa attgtatttg attatagaca
      361 gataatcgat tcctttgata aaaaggaaaa agtagcttat attaaagacg aagaaggcat
      421 atatatagat tgtagtgaaa atttaatacc aatattaaat aacaacatta aaacaacgaa
      481 agatatcttt ggtaaaaatg atatagaagt atggggagag aatacaggaa aattatttag
      541 agatgattat agagaaggag tatctagtaa aaaaagattt ttacaaaatc tttttgaata
      601 tgaagaaaca ttttttatgg ttgaaaaata ttttttgtat gatgaagacg aacttttagg
      661 tactataggg atagtagaca atataatata tagtggttac agtaatagaa attataactc
      721 aaaagattta atgaagatga tagaacactc aattccagag aatatgtttt ataaagatgt
      781 gtatggaaat tatattggat ttaattcagg ttttttgaat ttagcttgta tgaataaaga
      841 agaattatta gggaagaata gttataaaat atcagaagaa gaagctttaa tagataagat
      901 atttgaaagt gataagggtg tagttgaaaa taaaaaagta gttacatttg agttaaatat
      961 aagtatgaat gatgaaaaca agtgtattga gattacaaaa aggccgtttt ttgatagcta
     1021 tggaagtgtt attggaataa ttggaacagc aagggatata agtagaagaa aaagattaga
     1081 agaggaaatg gataaaacta ggatggaatt ttttgcaaat ttatcccatg aacttagaac
     1141 gcctataaat ttaatatcat cttcattaca agtgatagaa aaaaaagaag cagatttaat
     1201 agaatcaaat gatactttaa aaagaaatct aggtataata aaacaaaatg gaaatagaat
     1261 attgaggtta gtaaataatg ttatagactt tacaaaaatg caatcaggat atttagattt
     1321 taaaccagaa gaatctgata taattgcatt tatagaggag atatgtatgt ctgtagctga
     1381 ttttgcaagc caaaataata tacaacttac atttgataca gaaatagaag aattttcaat
     1441 gttatttgat tcagaaaaat tggaaagaat aatattaaat ttactttcta atggaattaa
     1501 gtacaataag aaagatggaa aaataaatat atttttatat gtgaaagata atgtatttaa
     1561 tatgaaaata tctgatagtg gtataggtat accaaaagaa aaaatagata aaatatttaa
     1621 taggtttgaa cagattgaca atgaactttc ttacagagtt aaaggaagtg gtattggact
     1681 ttcattagtg aaatctttgg ttgagttgca tgagggaagt atatctttaa aaagtcaact
     1741 tggtattgga agtgaattta tagtttcatt gcctgttaga agtaaaaata atattgaaaa
     1801 atataatcat aaaagagaaa tcagcaatga actaagtaaa aaattagaaa tagagttctc
     1861 ggatttataa gtttaaatat aaaaaataaa attttaaaaa agtattgaca attgatttag
     1921 aagggtttaa aataaattac aacataataa ataaaaaggc gatgaatagg aagagtaaat
     1981 ctaattcgat taccagagag aagagtccgt tggctggaag actttttaaa ttagagggat
     2041 tgaaaactac ctaggagcta ctttctgaag tcatctgcat tagtagattt tagtaagaat
     2101 agtcgttagc tgcgttaaag tgtaaagtga gttttcatga catatgaaaa ctaaattagg
     2161 tggaaccgcg ggaataatac tctcgtcctt atgttataag gatgagagtt ttttgttatt
     2221 taaaaatata aacagtaatc ataataatta tagaaaatat aaaagcaatg aataggaaga
     2281 gtaaatttaa ttcgactatc agagaggaaa gttcacaggc tgaaagactt tctaagtttg
     2341 agaaattgaa aactacctag gagctgtggt ctgaagttac tttaaaaagt tttagtaaga
     2401 ctaaccgtta actgcgttaa agtgtaaagt ggattttatc aataaatgat aaaatcaaat
     2461 tgggtggaac cgcgagtata gactcgtccc tttatatagg gatgagtcta tttttattgc
     2521 aataaaagat tgaaaataaa aaaaatcgga aaattataaa tttaggagga aaataaaatg
     2581 gagaataaag tgaaaattgg agtactagga tatggagttg taggaagtgg acttatagat
     2641 ataatagata ataataaaga aaaaagaaat atagaaatag ttggaatttt agttaataat
     2701 ttggaaaaac ataaggataa aaaatattct aatataataa ctaataatat agatgatata
     2761 tttaataaag atatagatat acttgttgaa gtcatgggtg gtttagaacc atcattatct
     2821 tatataaaaa aagcattaaa cactaaaatt catgttgtta cagcaaataa agatttgtta
     2881 gctgaatgtg gagatgagct tgcaaaatta gcaagtgaaa ataaagtaag tattaaattt
     2941 gaagcttcag ttgcaggagg tataccagta ttaaaaccaa taatagaatc actagaagga
     3001 aataatatag atagtataaa tgcaatttta aatggaacta ctaattttat attatctaaa
     3061 atgtatgatg agaatctatc ttatgatatg gcattaagac aagctcaaga attaggtttt
     3121 gctgaagcaa atccagagtc agatgtatta gggtatgatg ctgctagaaa actatcaata
     3181 ttatcaactc tagcttatga caatagagta tattggaagg atgtgtattt agaaggaatt
     3241 acagatatag atgaaaaaga tattgaatat gcaaaaaaat taaattgtaa aataaaattg
     3301 attggtcaaa gtaagtatga aaatgataaa gtaagtgctt ttgttagacc tgttttagta
     3361 gaaaaagata atatccttgc tagaatagac aatgagttca atgctgtcat agtgaatgga
     3421 gattcagtag gagaagtttc ttttgtaggt aaaggcgctg gaagtttagc aacaggaagt
     3481 gcggtttatt cagatgttat agatataata gataatagag tttcaagtat agattctttt
     3541 actaaagata aaatacaagt taataaaata gttagagaaa agtgtggagc acttcttaga
     3601 tttaaaaaat gtaataaaga tgaaattcta aatatagttg agaattgttt agtaaaattc
     3661 gatattttaa atgatgatga tgaacttgct attatggttt atgctgattc tgaatatgaa
     3721 ataaacaaca gtttatgtct aataaaagat aaaggatact gcgaaaaaat gaataaaatg
     3781 ttgaaaataa gttaaaaaag aaaaaatata agtttatatg taacatattt tgacgatttt
     3841 aatactatat agtatgagat gaaacaaaac atctcataaa aaaattaaaa ttcaagggag
     3901 agatatgtta tatggaaaat aaaaaatatg caaatggtgg ttattcagaa gactggtatg
     3961 aaagaggaga atctacagct aaatggttcc agaatgatag agaagaatat gaaagagcag
     4021 catacgatga agatagagaa agaagaggct caaactgtgg atgttcagat tcaggagaaa
     4081 atagacctag aaactgtgaa agatttagaa gagaagcaga gataagagaa agagaagcaa
     4141 gagaagcatt ctgtgaatct tcagagagaa agaaagaagc actagcatat gaatgtgaag
     4201 ctagaaaatt atgggaagaa gcagaaaaat actgggatga atattcaaaa tacaactata
     4261 aaggaatcga atatttagca gaagctgcta gattatttga tgaaggtatg gaatgtgaag
     4321 ctagaagaaa tggaaataat ggaggaaaca ataataattg ttgccataaa tgccataaat
     4381 gtaattgtaa ctgctgtaga aaataaaaaa attaattgac aaatcaatag ttaaaatata
     4441 tcatattatg tataataaag agaaaattca gaaaaaaata atgattagaa gaaatataag
     4501 tatatttatt agacaaatag tgctcagtta gtgaggtgag tacaatatga ttaaactccc
     4561 atcctctagc ttttgataga gggtgggagt ttttatttat ttatatatct taaatgagga
     4621 taatattgta aaataaatga gtatgagatt gtaaaattag gaggtaaaaa atgaagagta
     4681 ttaaaacatc aagtatgaaa gaaaaggtag atgaaaagat attaagagag caagtaagtt
     4741 ctataataga agatataaga aataataagg atgttgcact taaaaaatat aatgagaagt
     4801 ttgatagaaa tacaagagat gaatttagaa ttactaagga agaaataaag gaagcttata
     4861 agcatgtaga tgacgaattt ataaataact taaagattgc tgccaaaaat ataagagaat
     4921 ttgctaaagc tcaaaaacta agttttgaaa acccttttga aaaagaaatt tatccaggtg
     4981 taatcttagg tcaaactaat attccaatag agtcatgtct tgcatatgtt ccaggaggtc
     5041 agtatccatt gttttcaaca gctcttatgc ttataatacc tgcaaaagta gcaggagtaa
     5101 aaagaatagt ggcatgttca ccaactatga aaaatactga aaagataaat cctaagacat
     5161 tggtagctat ggatatagca ggtgctgatg aaatatatgc aactggagga gttcaagcta
     5221 tagcagcatt tacatatgga acagaaaaga ttaatccagt tgacataatt gtaggaccag
     5281 gaaataagtt tgtaactgaa gctaaaagac aatgttatgg acaagtaggg attgattttg
     5341 tcgctgggcc aagtgaagtt cttataatag cggatgaaac ttcaaatcca gtttatattg
     5401 cagctgattt attagcacaa tgtgagcatg atttaaatgc aagaggaata ttattgacaa
     5461 atagcttgga agtagcacaa aaagttgaaa aaaatataga aagtatgcta aaagatttgc
     5521 caacaaagga catagcatat agttcatggg aaaataatgg agagataata ttggttgatg
     5581 atatggaaga agccattaaa ataagtaatt tttatgcacc agaacattta gaagttgcag
     5641 taaatgagta taatgatatt tgtgatagat taactaacta tggttcttta tttattggaa
     5701 atctttctgc tgaggtgttt ggtgactatg tttcaggtac caatcataca ttaccaacac
     5761 ttaaagcatc aagatatact ggtggtgttt gggttggaac ttttatcaaa acttgtacaa
     5821 agcagatatt taatgaaaaa gctatacaat cattagcacc tgtagctgaa aagctggcaa
     5881 aagaagaggg attatatgca catgcaaagg ctgctgaggt taggtttaaa aagtagtaaa
     5941 aaattttatt ttggcagtcg agatttagtg ttagactgag ataaggaaaa cgctgagaac
     6001 ccgaataaat actatatttt gtgggcctcg gcgtttcttt tatatctgta tataatagga
     6061 taatactacc tgtgtgttta aatgctagct taatatttct tttctaaata atgtttatga
     6121 aatagttaat atttttagtt aatacttgaa aaaaactttt gctaactgtg caaattcatc
     6181 tgcattcgtc aatatagcag ggtgtcctcc ctgactaaaa atgtgaatac ttgcttttga
     6241 aataaaagtt gccatttgtt tgtactcttc ttcaagatta tgacgacaca tttcgtcttc
     6301 cttacttcct gtaaataaaa ttggcatttc taatttacac aattctttat gaaacaaagg
     6361 gcgtttctcg tttgcacatt gcaatagagc ttttgtatca agattaacaa cattctccca
     6421 atcttttcca tgacaccatt catagaattt tcgtgcttga atatcttgct ttgatttttc
     6481 ccttccagtg attagattat ctatgaagtt atcattaaga gtacgtccat caaagctatc
     6541 tgctataatt gcttcaacta aatcgggacg ttctaatcca gtattaacag ctgcccatgc
     6601 tcctccactt gttccaatta agccaacttt accacaattc aaatgttcaa tcaatgctat
     6661 tgtctgtaag gcttcatcat gccatatgtc aggagaaaat tgagaaactc tatccgactg
     6721 tccattacct aaaaaatcaa ttaagataca tctaaaattt tctacatata atggcacaag
     6781 tgctttaaac atattagaag aaccagtatt accatgcagg aaaattatcg gtttaccttg
     6841 tccatattct ttataaaaac aagaattacc ttgatactga aaatatgaca tatattttcc
     6901 tcctttttat ttgttaagtt aattataaca atataggtat gaatgaaaaa cctcatgttc
     6961 tttcttagaa taaaaatgtg ccacgcataa aacgtgacac atttctaatt ataaattttg
     7021 ctgtttaagt attctttgta tgcttttctc tgtcaaaaag tatttctctg ataactgctt
     7081 gatactcatt ccattttgga aatttataca gatttgagaa ttacgagaag ctaagacttg
     7141 tttggtgttt gtgttttcac cccaatgctt tttgtgctct tgctttttgg gaatataaat
     7201 cactttacca tctatatatt cttgcacttg ctcaatcagt tctttaggca gtaagtcaat
     7261 cgaattttga tagctcattt tgcacctcct aaataattat tctttaggat tagcaaaggc
     7321 tactgccact cacaattaaa aataaaattt tttattatgt acaatagcct ttgctatgca
     7381 caagttccaa ttcccataaa ctaaatactc ctttctggtt tgaaaaattc atctgaacat
     7441 tgatttcgct tttaagatag agttcaatga caaatttaca tttttattat atatattcag
     7501 atagataatt gcaactgtct ttgtatgagg atattttatt atagtcaata ctataatatg
     7561 tatttatatc atcaaactaa tatgaacagt tgaaaggaat atgaacaata aaacttagtc
     7621 aggaagaata attatgaagc agacaataga gaaatttgat tttaaagttt tattgaaaat
     7681 ttattgacaa atttaacttg taaatattat actaaactta ataaataaag tttataaagt
     7741 aaggtgttgt ctatgaaaaa tatagttgga aaaccgcaaa cgataaaaaa agtaaatgaa
     7801 gatttaataa aaaatattat aaaaaatgaa ggtcctataa caaaaccaga aatttcaaac
     7861 attactgaat tgagtttagc tacagttaat aagattgtag agcaattagc tttgaaaaat
     7921 gaagttaaag taagtggact aagtgaatct actggaggaa gaagagctca attatttgaa
     7981 ataaatgcaa acttagaaca cataatagct ttatattatt atagaaattg ttgtataggg
     8041 gtagttgcca atttattagg tgaaataatt tatcaagaag aatttaatat aagaatggat
     8101 acatatgaaa acgttaacca agatactttt tttgttatag atactctaat aaaaaaggaa
     8161 aaaggaaaca atataagggc tattggaatt ggtgtcccag gagttgtaaa aaaaggtgta
     8221 gttaaaaata taccaactat aaaaagttgg gaaggtataa atttagaaaa tttaataaag
     8281 agtaaataca atactaaagt gtttatagaa aatgatacaa atattactac tattgggatt
     8341 tatcaaaaac agtataaaga caaatataaa aatatggctc ttatgtattt agaagatggt
     8401 attggttcag gtatagttat aaatggtgaa ttgtatttag gttctacaaa ttttgctgga
     8461 gagttaagtt atctaaatat agaatttggt aagtataact ctaacaactt aaatcttgaa
     8521 gattatatta tgagtttaag aaaaagatat ttagaaagta aagataataa atttaagaaa
     8581 gaaattttat ctataatatc aaactttata aggactcttg tatgtgtcct aaatccacaa
     8641 gctatgatta tacagtgtag tatattaacc aagagtgaca tggagtttat agaaaaagat
     8701 gtaagcaata atgttggaga agaaaatttt cctaaattaa taaaagtaga gtcattgaga
     8761 gaaggaagta taaatggagt aattagtatg tgtttaaaag aaactgacta tcaatattcc
     8821 ttatctaata aaaaaggagg atattaatgt gaaatatttg gtttcaatag atggaggggg
     8881 aacaaaaact aaattttgtg taagtgactt agatggaaac atacttaaag aacataccac
     8941 tggttcaact aattataagt cagttggaat taaaaaaaca tatgaaaata ttaataatgg
     9001 atttaaaaaa atattaaaag atttatatat cgattatgac gatattgagt acactgtatt
     9061 tggtatatct ggttgtgatt ctcctaatga ttataagatt ataatggatg aaatattaaa
     9121 aattgggatt aacaaagaaa aaatatatct ggcaaatgat gcagttttag ctttttatgc
     9181 acaagcggat tcccctggtt tagtaattgt ggctgggaca ggttcaatta tactgggaat
     9241 taaagaagat ggagaaatat atagagttgg tggatggggg tataatttta gtgatttggg
     9301 ttctggatat gatataggga gaaaattatt aaagaaagta ttgctttatt gtgatgaatg
     9361 tcatgagtat agtgatttat ttagttgtgt cttggatttc tttggagcaa atagttttga
     9421 acaacttgca tatatgatta ctgatataaa caataatgtt gaaatagcaa acttagcttc
     9481 attagtgatt gattgtgccg aacaaggtga taaattggct attgaaatat taagagaatc
     9541 atcaactgaa ctatctaaat tagctcaagt aatattgaga aaaatatcta atccaatgaa
     9601 agtggataaa agcgaaataa atatagtttt gtctggtggt acattaaata aaactgtata
     9661 tgctcaaatg ttaatgaata atttaaaaac agaaaataca gataaaaatt taaaatttat
     9721 atctcaagaa aatcagccag tgtatggggg gataagactt gctatggcat tagctaatag
     9781 gagggtcaag catggataga aaaaaggtaa tagtacaaat ttttactgga ggttttaagg
     9841 ctaaagaaat aaagtttaat gatataaaat gtaaactact agaattattg gactgtattg
     9901 atatagaaaa ggttatcatg ggatggagtg tagatgaaga attatatgta gaaactaaaa
     9961 aactattaaa taaatataat gttgaactat atctttggtt gccatgtttt tctgaaatag
    10021 gattacttga aaaaagtaat ttgctaattg attatatggg gaaggaagtc aagggctatg
    10081 ctttacaaga ggatgaaaat tttgagtttt attgcccaaa taataaggaa aatataaaaa
    10141 atataaagaa aatatatagt acttatttta gtgatattaa atttgatgga atttttttag
    10201 ataaaataag gtatggttct ttttcgaata aactaaatgg tgtttttaat tgtttttgta
    10261 aagattgttt aaatatatat gaaaaaaata atattgataa agagtcgtta atgagagaaa
    10321 tgaataatgt gtctaaggga gttatagata atgaagatac tccatttggt ataacagaat
    10381 acattaatgg aaaatacaaa tttaaaaata aaatatggga agattttttt gaaacaaaaa
    10441 atcaaaatat atacaaggca ttattagaga taagtaatta ttttaaaagt aagggattga
    10501 aaataggtat agatactttt tctcctttta tttcttactt tacaggtcaa gatttagaaa
    10561 aattacaaga agtagcagat tttataaaac caatgatgta tagaactaca aaagctccag
    10621 ctggtttacc atttgaattt gaaaggttta ttgatgaatc catacataag aataaagaga
    10681 ttggaaaaag aaatttctta gatattttag gaattaagga gtatgaagga gatgtatatc
    10741 ctatagaatt tgtactagag gaaatcgatt ttatgacaag aaatcttaat aaagatatat
    10801 atgtaggagt tgaaataaat aaaaaggaaa ttatatctcc tgttacacct aagtacataa
    10861 gtgaaaatat ttcaaatata aataagacaa cagtaaaagg atatgtttta tcttgggatt
    10921 tgttgtcagc accaaaagaa aatattgatg aaattataaa atggtttcgg aattagtgag
    10981 gtgataaagt gagtaagata ttggaaatgc aacaaatata taaaagtttt ggaaaggtag
    11041 atgttttaaa agggataaat tttgagttag aaaagggaga agtaagagct cttttgggag
    11101 ctaatggagc aggaaaatct acacttatta aaattttagg aggagttcat tctcaaacta
    11161 aaggtaaagt aattttgact ggtaatgaaa taatgtttaa aaatccacat cattctaaag
    11221 aaaatggtat tagtataatt tatcaagaat taagcttgat accaacgctt acagtacttg
    11281 aaaatatttt tcttggtaga gaaattttaa aaggaagtgt gtttttaaac aagaaagaca
    11341 tgcttgagga atgtatgaaa atttgtgagg attttgattt taatatagac ccacatatgg
    11401 tagtttctaa tttaagtgta gcaaaccaac aaatggttga gataatgaaa gctgtttcat
    11461 gtaattctga aattatcata atggatgaac ctacaacatc acttactaat aatgaaaaag
    11521 atgggctatt taaaataata agtagactaa agtctaaagg taaaacaata gtctatattt
    11581 ctcacatatt agaggaagtt tttaaagtat gtgatagtgc aagtataatg aaaaatggaa
    11641 ttatgattgg aacttatgat gtagaggatt taactaaatt aaagataact caacttatga
    11701 caggaaatga taatcacaaa cttattgaga agaaggatta tacatttgca aaatatgaag
    11761 agccaccagt actagaagta aagaatataa gctggtctaa caaaataaaa aatgtttcat
    11821 ttaaagttta tagaggcgaa gttgtaggtc ttgcaggtct tgtaggttca agaagaactg
    11881 aaattataaa tttgatattt ggtatagata ataaagatag tggagacatt tttatcaatg
    11941 gtaaaaaagt agacataact tctcctaagg ttgctataaa aaacaaaata ggattgattc
    12001 ctgaagatag aaaaaatcta ggattaattt tagaacaagc tatatacaca aactcatcat
    12061 cagtacaaat tgataaattc aagaaattct tgtttataga tagaaataaa gaaattgagt
    12121 tttctaaaaa aggtgttaag gaattaggaa taaaagttaa tgatgtaaag caagaagtaa
    12181 aagagcttag tggtggaaat caacaaaaag tagtagtttc taagtggtta gagaaagatt
    12241 tagatttaat aatatatgat gagccgacaa agggaataga tattgctgca aaagaagata
    12301 ttttcaatac aatcaaagaa ttttcaagta aaggaatagg agtaatattt atatcttctg
    12361 atttagaaga agtaataaga gtaagtgata gaattttagt aactagagaa ggttctattg
    12421 tagatgattt aaaaaatgag aatatacagg ttcaagatat aatgaacagt atatttaatg
    12481 tataaaaaat gaaaatggag gactgaaatg aagaaagctt ttgagaagtt aaatttaaga
    12541 gattatggag tattattagg ttttttagct ttatgtatag ctataagtat tgcaactcca
    12601 tcatttttag gtaaacaaaa tatacttaat cttttacgac aatcttctat aattggaata
    12661 atttcagcag gtatgacttt tgttataata tctggaaact ttgatatatc agttggagca
    12721 gtagcagctc ttgcaggtgc tataacaatg aaatttgcga ctggtggaac taatttgttt
    12781 gcatccatgc tcttaggtgt agcgatttgt gcagtaatag gattaatcaa tggtatagta
    12841 gttgcaaaga taaatgtacc atcattaata gccactatgg ctatggtcac tattgtaaga
    12901 ggattgctgt tgatgcttac aggaggatat ccaattactg aaaatatacc aatacttgat
    12961 tacattggaa atggatattt gtttaatata ccaataccag tagtaatttt ctttatagtg
    13021 gtgttagctt catttattgt acttaataaa actaagtttg gtagatatgt ttattctgta
    13081 ggagggaatc aagaagcaag taaacttaat ggtataaatg tagattctca caaagtgaaa
    13141 gtatttatta ttaatgctgt acttgcagga atagctggaa tcgtactaac aggaagactt
    13201 gggactgcaa ctgcgattgc aggtgaagga tatgatatgg atgcaattgc atctgtagta
    13261 ataggaggta catcagtggc aggaggttct ggttctgtac ttaaaactgt tataggagta
    13321 ttacttatga gtgttataaa caacagtttt aatcttcttg gaatagatgt atatttccag
    13381 tacatattta aaggattaat aattttagca gcagttggat ttgattctta tagcaagaaa
    13441 aaacttgctt caagataaaa aataaggggg atttttttat gaaaaaatta atgaaacatt
    13501 tagcattgtt gctatcactt gttatgatat ttggtttagt tggttgttca aatggtggtg
    13561 acaaagaaaa aaatggagaa aagaaaatag cagtattact accaggttca acaggttact
    13621 ttgtagcaac taaacaaggt atagatgcaa aatctaaaga attaggtgta agcgtggaat
    13681 atgcagatgc tcaatgggat gctagtaaac aattatcaca agctgaagat tttatggcta
    13741 aaggggtaga catgattgca ttatgtggag ttgattctgc tgtaagtgag agaatagtta
    13801 aagctgctaa tgattcagac gttcctatag tagcatttac aaattctata ggaagtaacc
    13861 caactggaga atttaaaggt ttagttacat atataggaca aaatgaggaa gaaacaggag
    13921 cattaactgg aaaaattgct aaaaacttat taggagaaac tggtgggaaa gctgtattaa
    13981 tagaaggagt accaggaact actccacaag tattaagaaa aaaaggtctt gaaaaagaat
    14041 taaaagatag taatatagaa atagtttata atcaaacttc aaattgggag aaagagcaag
    14101 ctttaaaggt aacagaagat ttaattcaaa agaaaactga ttttaatgtt ataatatgtc
    14161 aagatgataa ttctgctaca ggtgcaggtc aagctttaaa agatgctggt cttaaggata
    14221 aagttaaagt cataggtttg ggtggaagta aagatggatt aaaagctata actgatgggt
    14281 taatagatgg tacaacttat atgtctgctg tagaagaagg tggattagtc atagaaaagg
    14341 catctaaatt ccttaaaggt gaaaaaatag aacctgttac acaaattaaa caagttgaag
    14401 ttaacaaaga taatatttca gagttcaagg gtgaatggta aattgtcata gataataaat
    14461 aagattttta gagttacttt agaaactata taaagtaact ctttttttaa tttaatttag
    14521 tgataaatta ttgaatagta tttctaaaca aataaaaaat taatataaac aaagacttaa
    14581 ttatactaaa ttataagtaa aactaatata aacttatgga aaaaaggaaa acgtctaaag
    14641 tattggaatt actatagtgt aggtgtggta ttaaaaaaac ataaaaaaac ataaaaaaat
    14701 tgttgaaaaa aatatagaaa ttttgtataa ttaaagattt gaaaagtgcg gtatacaaag
    14761 ccaattcttt tgtatataat atatataaat tcagaaaaag gaagggatat gtatggccag
    14821 gcggttattt ttagaaagga ttggacttat atttttaggt tcagcaatat tagcatttgg
    14881 agtttataat ttttattatt taaacaacat aacagaaggt ggagtgttag gtattttact
    14941 actgttaaaa aatttattca atatacaacc agcaatagca aatgttgtaa tagatggttt
    15001 gctactttta gtaggatata aatttttcgg taaaaaattc cttatatatt caatagtagc
    15061 ttctataact ttttcagtgt tatatgactt atttgaagct ataggacctc tagtaccaca
    15121 atcacaaaat atgcttttat caactatttt ggcaggtgta actgttggaa ctggtgtagg
    15181 tatagtagta aaagcaggtt gtgcatcagg aggagacgat gctttagcat tagtaatttc
    15241 taagactaca tctttgaaca tagggcaagt ttatttagca acagatgtta ttgtattgtt
    15301 gttatcatta ttttatctat cagcgtttga tatcttttat tctttgattg ctgttacaat
    15361 tagtggcaag gtaattgatt ttatttatta tcatggtaaa agtttggata tggatataag
    15421 taatgatata gttccagaat gttaatataa attaaataac tttagatttt attaggggtg
    15481 gcagatttgc cacctttttt gtgtctaaat ctttatagaa agtataatcc tatctaggtt
    15541 tttgcaaatc tcaaatatag aattatgttg aaatgactgg gaatacgatt gctagatgtg
    15601 cattttaaaa acccaatttt atatttatga aatactaatc attaatggat gtttcttaat
    15661 cctatcttta tacctaaaat gataagataa atgaagtagc aatacaaaac taaaatttgt
    15721 aaaagagatt aaattaaatg gaggagctaa aatgttggat atagttatga tagcattgtt
    15781 attcatagga tttgtttcca tgaagttact tgctgattgg tgtgggaaac aaactgaaaa
    15841 aaaataatgt aatgtatgga gggattacct atgtggtttc tggcagttgt aattataatg
    15901 ttaataatat atttggtata tgcgcttatt aatcctgaaa aattttaaac agtataaggc
    15961 taataagtaa gttgaattgg ggggaacaat ttttatggtg cagatagtaa tagtgttagc
    16021 gatttttatg attttagtaa tacctatggg caagtattta tatcatatag ctactaatca
    16081 aaaaacattt ggagatagac tatttgataa agtggacaat tttatatata aggtatgtag
    16141 tatagataag aaaaaagaaa tgaactggaa acagtatgca ttagctttat tatttacaaa
    16201 tgcagttatg gtatttatag gatatatcat acttagaact caaagtatgc atatttttaa
    16261 tccaagtgga attaaaagta tggaacaagg actatcattt aatacaataa taagttttat
    16321 gacaaataca aatcttcaac attattcagg tgaatcagga ctttcatact ttagtcagat
    16381 gacagtgata atatatatga tgtttacatc agctgcaaca ggatatgcgg ctgctatggc
    16441 atttgtaaga ggtctagtcg gtaaaaagaa aacattggga aatttttatg tagatttaat
    16501 taggataaca acaagagtac ttttaccagg agctttaatt attgggctta tattagttac
    16561 acaaggagta ccacaaactt ttgctgggac agaaacagtg actactatag aaggaaagct
    16621 tcaagatata gctagaggtc ctgtggcagc tcttgaatca ataaaacatt taggaacaaa
    16681 tggtggtgga ttctttggtt caaattcatc acacccattt gaaaatccaa caataatatc
    16741 aaatatagta gaaatattat ctatgatgat attaccagga gcttgtgttg ttgcatttgg
    16801 tcacatgata aagaataaaa aacaaggttg ggttgtgttt ggcgcaatgt caatcatatt
    16861 tttaataggt ctagtagtgt gctttaaagc agaaagtgca ggaaatccta ttttatcaca
    16921 attagggctt aatcaaagta tgggaagtat ggaaggtaag gaagttagat ttggtatagc
    16981 acaatcatca ttattcacaa cagtgactac ttcctttacg acaggtacag ttaataatat
    17041 gcatgataca ctgactcctt taggaggatt agtaccactt ttaaatatga tgctaaatgt
    17101 agtatttggt ggtaaaggcg taggtctgat gaatatgttg atgtacgcta taatagcagt
    17161 attcttatgt ggattaatgg taggaagaac accagagttt ttaactaaga aaatcgaagg
    17221 aaaagaaatg aagcttattg ctttacttat tatattacat ccacttttaa tactaatgtt
    17281 ctctggtctt tcagtagcaa taccagcagg acttgaagga atttcaaatc ctggattcca
    17341 tggattatca caggtattgt atgagtttgc atcttcagca gccaataatg gttcaggatt
    17401 tgaaggtcta ggagataaca ctatgttttg gaatataaca acaggtatag ttatgttctt
    17461 tggaagatat gtgtctatta tagtactact agcaatatca agtttgttag catctaaaaa
    17521 agctgtaaat gaaagtatag gaacacttag aacggataat tttacattta caatagtttt
    17581 agtacttgtt gttttaattg ttggtgcttt aacatttttc ccagccttag cgcttggacc
    17641 tatttcggag catctagtgt tgtggcacta aaaaattggg agggagtaaa gttttatgga
    17701 aactaaaaaa acaaagttta ttacaaaaga tattttcaaa acttccatta tagaagcttt
    17761 taaaaaatta aatcctaaat atatgatgaa aaatccagtt atgtttgttg tagaaattgg
    17821 atttatagta acattgatac ttacaatagt acctagtttg tttggtgatg aaggcaataa
    17881 cttaagagct tataatggga ttgtaacaat aatcttattt ataacagtcc tttttgcaaa
    17941 ttttgctgaa gctgtagctg aaggaagagg taaagctcaa gcagatacac ttaagaaaac
    18001 tagaaaagat acagtagcaa gggttataga tacgttagga aatgaaaaaa tgataagtgc
    18061 aagtgagcta aaacttggtg atattgtttt agtaaatgct ggagaagtta tcccaaatga
    18121 tggagaagtt atagagggta tagcttctgt ggatgagtca gcaataactg gagaatctgc
    18181 acctgtcatg agagaatcag gtggagattt cgcatctgtt acaggtggta ctacagttgt
    18241 aagtgactgg ttaaagataa gaataacaac aaaaccagga gaatcgttct tagataaaat
    18301 gatagctctt gtagaaggtg cttcaagaca aaaaacgcca aatgagattg ctttaaatac
    18361 tttgttagta gggttaacac ttatatttat ggttgtttta atatctcttt atccaatggc
    18421 aaactatgca ggtgtaaaga ttccaatttc tactatgata gctctcttgg tatgtttaat
    18481 accaactact ataggtggat tgttgtcagc tattggtatt gcaggtatgg atagagtaac
    18541 tagatttaat gtaattgcaa tgtcaggaaa agcagtagaa gcttgtggag acgttgatac
    18601 tatgattttg gataagacag gtacgattac ttatgggaat agacttgcat cagaatttat
    18661 agcagttgga aatgcagatt caaaagattt aataaattat tctgttatgt gttcattaaa
    18721 agatgataca ccagaaggaa aatctatagt tgatttaggt atgaaattag gttcaacagg
    18781 taagacaaaa gaggcagagg aagctgagtt tgtagaattt tctgcacaaa ctagaatgag
    18841 tggtattaac ttagctgatg gtagagctat aagaaaaggt gcttatgata gcataataaa
    18901 aagagtaaaa gaatctggtg gtacagtgcc agaagattta gaagaaaatg taaatcgagt
    18961 agctaaacta ggagggacac ctttagtagt gtgtgtagat aatgagatat atggaattat
    19021 ctacttaaaa gatacagtaa aatcagggct tgtagaaaga tttgctagac ttcgagagat
    19081 aggaataaag acaataatgt gtacagggga taatcccttg acagcagcta caattgcaag
    19141 agaagctgga gtagatggat ttattgcaga atgtaaacca gaagataaaa tagatgcaat
    19201 aaaaaaagaa caattagagg gtaaaatagt tgcaatgaca ggtgatggaa caaatgatgc
    19261 tcctgcactt gctcaggcag atgtaggtct tgcaatgaat agtggtacaa catctgcaaa
    19321 agaagcagca aatatggtgg atttagattc agacccaact aagatattgg aagttgttga
    19381 aataggaaaa cagcttttaa taactcgtgg ggctttgaca acatttagta tagcaaatga
    19441 tgttgcaaaa tattttgcga ttataccagc tatatttact cttgcaatac ctcaaatgga
    19501 gatattaaat gtaatgaaac tttctacgtc atttagtgcg atattatcag ctttaatatt
    19561 taatgctata attatcccat gtttaatacc tcttgcaatg aagggagtaa aatatagacc
    19621 tatgaaatca caagctatgt taatgagaaa tatgcttata tttggtcttg gtggagttat
    19681 agtaccattt ttaggaataa aattaattga tttattgatt acacctttag taatggttct
    19741 taatttaggt taataaatgg aggatataaa aatgaaaaca ttaaagccag cattacttgt
    19801 aagtattgta ttgttagttg tttgtggact tgtatatcca cttgttttga caggtgtaag
    19861 ccaagttgca tttaaagata aagctaatgg aagtatgata gaagtaaatg gtgtaaaagt
    19921 aggttcagaa cttattggtc aaagctttac agatgcgaga ttctttaagg gaagagtatc
    19981 atcagtaaac tataatactt atacaaaaga agatttagta ccagataaag atggaaacac
    20041 atcttatgga ggtgtatcat cagggtcttt taattatgga gctacaaatc cagaacttca
    20101 tgatagagta caaaaagata tagaacagtt tttaaaggat aatccaactg tcaaaagaga
    20161 ggatatacca acagatttac ttacagcatc aggttcagga cttgacccta atataagtcc
    20221 agcctctgca aaaattcaga taccagctat agcaaaagcg tctggaatat cagaaagtaa
    20281 attacaaaaa attgtagaag ataatacttc caaaaaactt tttggagttt taggtgaaga
    20341 tagagttaat gtattaaagg ttaatgtaga ggtcgcaaaa atattaggtc ttatatagta
    20401 ttttgtggaa ttttagcaac aaaatattac tcaagattta atttaaaggt taaattttaa
    20461 agagtgaaaa tcgataatga ttttcacttt tttatttgaa tattactaat atttggaata
    20521 aagtgattgt aagtataaaa tccaaaaaaa ggttgcatta tcaaaatgat aatactataa
    20581 tatatttatc gttatcaatt tgataataga tttggacata taggaggaaa tagtatgtta
    20641 tataataacg cattagagtt gataggaaac acacctgtag taaggctgaa taatttaggc
    20701 tgtactaatg ggtgttctaa catatatgta aaattagaaa aagtaaatcc agcaggaagt
    20761 ataaaagata gagctgttta tgaaatgtta gagggtttag agcaaagagg agaattaaaa
    20821 aagggagatg tactagttga agcaactagt ggaaatactg gtattgcatt atctatgata
    20881 ggaaaattaa aaggatatga agtagtaatc gtaatgcccg aaacaatgag cgttgagaga
    20941 agagatttaa tgaaggctta tggagcaaat ttggtgctta cagatggtaa agctggaatg
    21001 gcaggttcca tagaaaaagc aaatgaactt ttaaaagaaa atccaaacta taaaagctta
    21061 aaacaatttg aaaataaaga taatccaaat gcacattata aaacaacagc agttgaaatt
    21121 atgaatgatg tcaaagattt agatatattc gtatgtggag ttggaacagg tggtacttta
    21181 ataggaactg caagatattt aaaagaacaa aatccaaata taagagtaat tgcacttgaa
    21241 ccaaaaaaat ctccagctat atcagaaaac aagactggac ctcataaaat acaaggaata
    21301 ggtgctaact ttgttcctga aaattatgat tctagtgtag ttgatgaagt aatattagta
    21361 gatgatgaag atgcatttga tacagttaaa ttacttgcag caaaagaggg aattttagta
    21421 gggatatctt ctggagcaaa tatatttggt gctatagaga tggcaaaaaa gtatccagat
    21481 aaaaagatag ttacagtagc tccagatgga gttgataagt atatgtctat gggaatattt
    21541 taataatttt atttgaggga gtgaatactt tgtttaagaa aataaataaa gatattgaat
    21601 atataatgaa gaatgatcca gcagctaggt ctaagataga agttttttta ctttatccat
    21661 cagttcatgc aatgataatg cataggatgg ctcatgctct ttataagaag aagaagcttt
    21721 ttacagcaag attaatatcc cagatatcca gatttatgac tggcatagaa atacatcctg
    21781 gtgctaaaat gggggaaggt atattgatag accatggaat gggtgttgta attggagaga
    21841 cagctgaagt aggtaatagg gtgacaatat atcaaggagc tactttagga gctacaggaa
    21901 aagatactgg aaagagacat ccaactgttg gtgatgatgt attaattggt gctggaacaa
    21961 aaatactagg acctttaaat ataggttcaa attcaaaaat tggtgcaaat tctgttgtcg
    22021 ttaaggatgt acctaatggt gcaacagttg ttggtatacc agcaaaaata gtaaaaataa
    22081 gaaacctaga acctgtaaaa aagaataaaa aagaagtgtc ctatgagtat gatgaattag
    22141 ataatgtata ttatatatag gatttatata actataaaat aaactttata aaaattattt
    22201 taaaaggtat ttttttcaaa tttgaggaca taataaaaaa gaactgaatg ttacagtttt
    22261 ggttcatcaa tctttgataa acaagatttt aaatttgtag cgtctaggag gattttatta
    22321 tgaaagcaaa tgttaatcaa gatacttgta taggttgtgg attatgtcca tcaatatgtc
    22381 cagaagtatt tgatatgaag gatgatggga aatcacatgt tatagttgat gaagtaccaa
    22441 gtgatgctga agaatcagca gcagaagcta gagaaagctg tccagttgat gcaatagatg
    22501 tgcattaata aaataaatgc ctataaaaat tgaattttca atttttatag gcatttgtct
    22561 tttattcagt tagtatttca acacctgttt ctgtaactaa aaccatacat tcccattgag
    22621 cagataattt accatctttt gtataaatag tccaattatt ttcttcatca acaaaaattt
    22681 cgtgagttcc ttcatttacc ataggttcta ttgtgaatat catcccagga accaatagca
    22741 tctcagtccc ttttttagat acataactta caaaagggtc ttcatgaaag cttaatccaa
    22801 ctccatgacc acctatttct ctaacaacag agtatccatt tttctttgca taagagttga
    22861 taacatcacc tatatctcct aagaatcccc atggtttggc aacttcaaga cctttttgga
    22921 cacattcctt tgtaacttga actaattttt ttgcattttc gttaacatta cctatcataa
    22981 acattcttga agcatctgaa tagtatccgt taaaaatagt agaaacatct acatttataa
    23041 tatctccatc ttttaagata atgtctttac ttggaatacc atgacaaact tcattattta
    23101 ctgatgtaca tacactttta ggaaatccat tatagtctag tggagcaggg atagctccat
    23161 tttgtagtgt aaagtcatga accaacttat ttatatcttc tgtagacatt ccaatttcga
    23221 ttttatctga aatataatcc aaaatttttg tgtttattac agcacttttt tttatttcct
    23281 caatttgact ttcatttttt ataatatcat gagttggtac aatatgacct aacttagcaa
    23341 atgaatctat tttattatcc atatccatat gacatttttt atatttttta gtacttccac
    23401 accaacagct atcatttcta tttaacttca taacttttca tccttctttt attatttatt
    23461 taaattatgg gttacataaa ctattttaaa acataaccat tataaatatt ataacataaa
    23521 tactaagaaa tcctttatag atagtgattt attcaaagta taaattatta tatggttatt
    23581 gttgatgaaa agaggatagt taaatgtatt attggatatt agcgcactta atagtttagt
    23641 tcaagttttt caagaaaatc atatgttaga ggacaatttt cctttaaagt attttttgaa
    23701 tcttcatcaa gataataatg tacaaatgat tctgcaaaaa attcttctat aaacttgctt
    23761 atatatgcat gtgcaacttg cttagggtca taaagcttat atctttcctg agcaaatact
    23821 tccataaatt cttcagaatt tgatttttta tttaaaacat ttttatctat agcatgtgca
    23881 gtttcatgta attctaaatt ttttgatgaa tgtacatttg catagctagg gttactataa
    23941 cctattttag ccactataga attatttcta tatataccag gtacatcttt ccaagtcttg
    24001 cctgatctta cccaacatgg aggtaattga tattttaaat cactaaattc tggttcatca
    24061 gttagatttg aatttattaa ttttattttt atatcctttt ctttaagtgt ctgtaaatat
    24121 ttaatattta tttttgcaag tctgtttttc atattttcaa cttcatcttt atcataattc
    24181 aagtcatcag gaagtataag catttgttca attatatcta tactactgtc ttttatattt
    24241 tcagattctt catcaaattt atattgaaga gtattatttt catagatagt tatatttgta
    24301 ttattttcta tagaataaga gtgaatatcc tctaaatcta aaatattcat ttgttgtaaa
    24361 atatgttttg tttcgccact ccacactact aaagaaagtg aattaaaatt aattagtgga
    24421 ttttcttttg cttttatatc attgcttata tctacatcaa atacatattc aattgagtct
    24481 tctatgttaa gactatctgt attcttttta atatataaat acgcttgttt taagtctata
    24541 taaatctcat ctaaagattc gtcataaaat tctgataaat tattagtaaa gagttcttca
    24601 cttaaaagtt catttttatc agttatactt tcaattaaaa tattaatttc ttttatcata
    24661 ttgtaaatac ttatttttct atttgctttt tcactagata cattgcatgg cgcaagagca
    24721 atgcaataaa aatctttttc ttttttataa aaggctttaa gtgattttga taaaagtgta
    24781 aagtctacac ctatctgtaa gttgacctta agtgagtcat tttgtaataa ttcagtatta
    24841 tttcttttag ctgtatttaa attgttttcc ataatcattg cccccttttt attagggtat
    24901 cataattttt ttatatgtgt caatttgttt ttttgaaaat tataattttt ttgaaaattt
    24961 tattttttat aatttgtgaa ttttttatta tagaaataaa tatgttatta ttatgtcaaa
    25021 atttagcatt agattcatgt agagtatgtt ttatacatat attataatta attctttgaa
    25081 gattgcatat tcaaaataca caccattttt tttaattcta taatataata tttatatatt
    25141 taatgttagg atgtgattta aggtgtattt tacatatatt ataagatgta aagatgattc
    25201 tctatacact ggatatacca gtaatatagt tagaagaatg aatgaacata aattaggaat
    25261 taattcaaaa tacacaagag caaagggatt tgaaaaacta gaagtttatt ttgtgaccaa
    25321 cacaaaaagc aatgctatga agttagaata ttatataaaa aaattaacta gaaataaaaa
    25381 attgtctata ataaaaaacc caagtatact tataaattta attgataata aagaagatta
    25441 tattattggt aaggaaatag aacaattaac ataaatattt atagtaacat tataatgggt
    25501 gcatatggtg taaaaacttg acaataaata ctattgtaat ataatgaagt tataaatata
    25561 gtaaattaaa atagctaggg gagccaagag ctgagaggta taccgaccct tacacctgat
    25621 ctggataata ccagcgtagg aaagcttagt aaaaattcaa gtatgtatta tttgtgatat
    25681 atgctatttc taagctatac ctattgtagg tatagctttt ttaattaagt tatttaaatt
    25741 aaactttagg aggcaacaat gagtaattat aaaataccaa cacttacaat agccggctct
    25801 gattcatctg gaggagctgg gattcaggct gatttgaaaa cgtttagtgc aattggtact
    25861 tatggtatga gtgtaataac agctataaca gcacagaata ctaaaggagt ttttgctgta
    25921 gaggatttaa ataagaaaat aataaaaaaa caaatagagg cagtctttga agatatacct
    25981 ccaagagctg taaaaatagg aatggtttca agtcctgaga ttatacttga aatagttgag
    26041 aatctaaaga aatacaatcc aaaatatttg gttgtggacc cagtaatgat atctaaaagt
    26101 ggatattatc tattaaagcc agaggcaaaa gaaaacttaa ttaagtattt gataccactt
    26161 gcatacataa ttacaccaaa tataccagag gcagaagaaa taacaggaat aaaaatacat
    26221 aatgtagatg atatgaagag agtaggagaa gaaatactac aacttggacc taaatttgta
    26281 cttatgaaag ggggtcattt agatggagaa gcagtggata ttttagttgg taaaaatata
    26341 tttaaagttt ataaaagtga aagaattgat aaaaaaaata cacatggaac agggtgcaca
    26401 ttatcttctg caataacatc ttatctagca ttaggatatg aaataacaga agcagtaaat
    26461 ctaagtaaaa tctatataac agaagcaata aaaagaagtt ttgatatagg tcatggagta
    26521 ggaccagtac atcattttta taaatttgag taataaaaaa atattggagg tagaatatgt
    26581 ataatttaat taaagatgta aaaaaattaa atccattggt aattcattat actaataatg
    26641 taactataaa tgattgtgct aatgtaactt tagctgtagg agcaagtcct cttatgagtt
    26701 tttcatatga ggaagtagaa gaaatggtaa gtgtagcaaa ctctgtagta ataaatatag
    26761 gaactatgaa ctcaaatatg ttggatttat tcctattagc tggaaaagca gcaaataagt
    26821 acaataaacc tgttgttttg gacccagttg gagtatttgc aagcaaagcg agagcagaac
    26881 ttacaagtag acttttaaat gaagtcaaat ttagtgttgt taaagggaat gtatcagaaa
    26941 taaagtttat aggtggcttt aatgtaaggg gtaaaggtgt agattcattt gatgaagaag
    27001 aagattctac tgagataata agaaagattg ctgaaaagct tgaatgtgta gttgtagcaa
    27061 ctggaaaaat agatataata actaatggta aaggtacata taaaataaac aatggaactg
    27121 ataaattaaa aggaattaca ggaactggat gtatgactgc tagcttgatt gcaagtttta
    27181 tggctgttac tgagaatata ttagaagcag caacaatggg tgttcttaca atgtctttaa
    27241 gtggggaatt agctaattta aataatccac caataggtac atttaaagaa aatcttatga
    27301 atgctattta tcaaatggat atagatactt taagtaaaaa ttctaatatt gaatttttaa
    27361 attaataaag agtaagggag acttaaaatg attgataaag aatctttaaa aaaatgttta
    27421 aagttgtatt tagtaactga ctctgaaatg cttaaaggta gagactttta taaatgtctt
    27481 gaagatgcaa tatcttctgg aataacaact gtacaactta gagaaaaaaa tgcttctgga
    27541 agagagtttt taagaaaagc tatgaaactt agagaaataa ctaaacaata tggtgttaag
    27601 tttataataa atgatagagt ggatatagca cttatttgtg atgcagatgg agtacatgta
    27661 ggacagagtg acattgatgt tagagaggtt agaaagctta taggaaacaa taaaattcta
    27721 ggagtatcag caagaacttt agaagaagct atttgtgcaa aaaatgatgg cgcagactat
    27781 ttaggtgtag ggtctatatt cacaacatct actaaattag atgcaaaatc agcttcgttt
    27841 gaaactgtta aagaaattaa agaaaaagta gacatgccat ttgtactaat tggaggtata
    27901 aatttagaca atatagataa acttaaatgt ttagaaagtg acgggtatgc tataatatca
    27961 gctatattaa aagctgaaga tatctctaaa gaagtggaaa agtggacatt aaaaatataa
    28021 aattggctct ggtagtgaaa aaaatggaaa aatttgatat aatctaagag taaaatttaa
    28081 gcaattataa atgataaact tttctacata tactttttaa tcaagatata tgtagatttg
    28141 gttaaaaagg agctataaat gattaggata ttgttagtgt gtgttggagg catgtcttct
    28201 accctattgg taaataaaat ggagaaggat gcaaaaaaaa gaaatataga ctgtaaaata
    28261 tgggcagttg gagaaggaga tataaaatcg gagcttgata actttgatat tttacttctt
    28321 ggaccacaac ttagatttat gcttgatgac gtaaagtcta tagttggaga tagagctcca
    28381 gtatctataa tagatatggt aaactatggc acttgtaatg gtcatgctgt gttaaattcg
    28441 gttttagaaa tattaaaata aataataaaa gtggattcta tataatagag tccattttta
    28501 ttatttgtta ttaataggct taaaacttag cttaccattt ctttttttaa tctccacata
    28561 gcaagtgaaa aacttgaaca gcacaatatt aaaaatagta ggataacagg cagtatatct
    28621 ccaataagaa tagtctcacc aaatattaag ctacgtaaag cgttaataac atgggtaaat
    28681 ggattgagca tcactgctac ttttaatcct ccagataaac tttctatagg gaaaagagct
    28741 gaacttaaaa agaaaatagg aagtacaatt gcagtcataa ttgtttcata aactatttca
    28801 tttggcaata ataaacttat agaataagct agacttgata aaaagaaggc tgtcataaat
    28861 atcagtacta tcataagtag gattccacca atgccagatt ctatccttac tgagaagaat
    28921 atacttacta tacacaaaat agttacttct atgaaagaaa ctaagatagc ttctaataat
    28981 tgaccaagga cgattgaata cctactgata ggtgcaatta agactctata gaaacttcca
    29041 ctgttcttca ttataaagtt tataatacca ccactactac aagaagaaaa cacaaccagt
    29101 acaatgatac ctggtagtat aaaagcagta taattattga tatttatatt attcatagtt
    29161 tggtttgcaa tagaactata aagcacaagc caaagaaaag gttgtaatat agtaactaca
    29221 aatgagattg gatttttaaa acgccacttc atactacgcc ataagatatt taacattccc
    29281 attcctcctt taagcttttt ttagaacttg taagtgctaa aaatacatct tcgagacttg
    29341 gctctacaat ttctattgca tcaaattcta tatcatgttc taaaagccat ttatttatta
    29401 aagtaaaagc agttctacta tcgtttacac ttataaaaat tgaattttct cgtacgctca
    29461 taaactttac taaaccagta cttttaattg catctttata tttttttata tcttcagtat
    29521 tatggaaagt tatacgtagt atattttgtc taatgtaact acgtaaactt gatggtgttc
    29581 cttgtgctaa atcctttcca ttcttcataa tacaaatatt atcactcaat tgttcagctt
    29641 cttcaagata atgagtagtt agaaatatag ttgtgccata ctcatctcta atttttaata
    29701 acatatccca catagatttt cttgaatcga catccatacc aacagttggt tcatctaaaa
    29761 ataggatttt aggagatgat accatattca tagctatgtc caatctacgt tttacacccc
    29821 ctgaatatga tgaagtagga tattttaagt aactagataa gtcaaactta tcaattaaag
    29881 agtctattct ttgttttgca atctgtggtt ctactttata cattttactt tgaaatacca
    29941 tattttccat aagggataaa tgttcatcaa tagagatttg ctgtgctaca caagcaattt
    30001 gagtacgtat ccaagaagga ttatctacta aatcttttcc aaacattgtt acatttccag
    30061 atgtaggttt gtaaaaggta gtcaaaatat ttataagaga agatttacca gcaccattag
    30121 gaccaagtaa agaaaaaatt tctccagcat ttacattaaa gcttagagca tttaaagctt
    30181 tcacaccatt tttatattct tttactaaat tgtctatttc aatcgctaac atatattatt
    30241 cctcctcttt aagtggaaat attatctctg taatatagtt atctgggttt ccttttatca
    30301 acatacctgg tcctttaata aatacttctc tccaaggagt ttgtattttt atattatttt
    30361 catgaatata tttaaatatc atttcatacg tttttggaaa attactataa gagcctgtgt
    30421 gagtaaaaaa taaagctttt gttttaggaa attcttttgt agttataccc atacgatttg
    30481 gagtttcagc agttggaaca cataattcca tttctgcaac accagttttt tggtcaacat
    30541 catagtagca aaagaatggt gcaccgttag actttccttt tatagcttta aatacatttg
    30601 gaaaatactt tgttgcctca gtcataggtc cattataacg catggtagcc actgtgactg
    30661 attcgatatt tttgatttca attttgcaat tcattgttta cctcctaatg tgtgttcata
    30721 ttcttactag atttttaagc attaatacat ataagatttt gattagttga aaacatataa
    30781 tcttatctcg tttgcttgtt ttcaagtcta acataacata aaatatatat cctctcattt
    30841 gatgctccat tttgtaaagt tattatttaa gctttacttt agatttttta gcaaattaaa
    30901 ataaagcaat ttataaaata agtatttaca aattaagtgt attaatcgta taatacactt
    30961 aataggatac tagataaagt ctgaaataaa ggcgtatttt tttaaagtaa gtgtactatc
    31021 gtattaatac actagaatag gaggaatcat gaattttgaa ttagataata caactcccat
    31081 ttatttgcaa atagtaaagt atataaagag acaaatagta acaggagagt tgaaaccagg
    31141 agagacaata ccatcaagaa gagaaatggc acttaatcta aaagtaaact taaatacagt
    31201 tcaaagagca tataaggaga tgggtgatat gaatataata aatactttta aaaattatca
    31261 aagcagtgta acagttgatg aaaatatatt aaaaaattta aaattagagc ttataaatga
    31321 atcactatct gtttttatag aagatatgaa agcaataaat gttagcaaag aagaagtttt
    31381 aaaaataata gaagataagt attagttttt taacaaatag aaaacttagt ttagaaagtt
    31441 tatttataag catattggat gtggaggata gtaaatatga tagaaataaa gaatgtcagc
    31501 aaaacatata aaaggatgca agggcttaaa ataagaaaga tagaagcttt aaaaaatgta
    31561 agttttaata tagaaaaggg aaaaataact gcattacttg gtataaatgg tgttggtaaa
    31621 tcaactatgt taaaagcaat agcaggactt ataaacattg atagtggaga aattcgtata
    31681 gatggagaaa aaataaatga aaaggtatac aataaattgg cttttgttcc agatgtacaa
    31741 tctcacttta gcaatacaac aataaaagaa acatttgaat ttatggaaat tttttattca
    31801 aagtggaata aagaaaaatc aaaagaaatg atggacatat ttaaattgga tgaagatgaa
    31861 ataattgata acttgtcaaa aggaaacatt gcaagagtaa aattaatact tggattttgc
    31921 caagacccag agtacatact tcttgatgaa ccatttacag gaattgattt gtttaagagg
    31981 gaagagttta taggagtaat agcgcaatat atggaggaaa atcaagccat tatcataact
    32041 actcatgaga tagtagagat agaaagttta gttgatgagg ttgtaattct tgatgaaggg
    32101 cagattataa cttcatttaa tgcagaagaa ttaagagaaa gagaaggtaa atctatatta
    32161 gataagatga gggaggtata taagaatgaa taaacttcta tatctaataa atgtagattt
    32221 gagaagaagc aataagtttt atatagctta tatatcattt ttttcactaa ttacacttag
    32281 tttaaattta ttcgaaatta ataaatttaa aaattctaaa tttattatga acttagcaat
    32341 agaagatttt ggaggtatat tttatggact agggatactt agtaatcttg gttttatcca
    32401 aagtatattg ttctttggga tattgggact ttttatatac tatattttta tgtggaaaag
    32461 agagttcttt tcaaataatc aaagtattta tacacttatg atgttacctc aaaataagtt
    32521 taagatttgt atatctaaat caatagcttt gataacaatg atatatggtt ttttgataag
    32581 tcagacagca acattattta tatgtaaata tatatttaat ttcattttta gaaatatgcc
    32641 tataatcaat atgaactttg ccaaagattt atattattta aacttgaaga gtataccaat
    32701 tgattttatc tcttttatgg ctatctatgt atttttacta cttatagcta tttctattgt
    32761 aaattgctgt atattattta tcttttccta tataaataaa ttttatgtaa ttttaatcac
    32821 tttgctgatt atagcaggct tatatttttc aacaatatat ataaatataa tcactttatt
    32881 tagaaaatat tatagtctta taggatttca atttaacaat ttagtagcag ggttattaag
    32941 ttttttaatt ataatgttta ttctaaatgg aatatcttat ttgctaatta aaaagaaagt
    33001 atctctttaa ggaggggtgg tatgaaatta aaatctaaaa tatctatact tattatattt
    33061 ttgactttag caatatattt tagtataggt ttattaaata atgaagataa tttaaagata
    33121 aaaactataa aaggtgactc taatgaatta gaccatataa acataaattt tggatatgct
    33181 ttgaatggat atataaattc atattataca ataaatggaa gtaacaaaac caaaaagact
    33241 gaattaataa aactacaaaa ggatagtaag aacacaaata atttaattga tgtatctagt
    33301 ggttcagatt taattgcaca tgttggattt gaaatgaatg aggagtcaaa agatataaac
    33361 tttgtaatag atgagaaaaa agaagattta gaaaaaggtg tatttccatc agaaggaagt
    33421 gataaagaaa ttgaatatga aaaattagat atgaataatt ttacaaggac aagatataaa
    33481 gtagataaaa gtacagatga ttattatgca aatatactag catcaaaaag atataaaaaa
    33541 tacttatatg tatctgtact ttatgctaca agtgattcat cagaaaataa caaagaatat
    33601 tcaagtacta tagatataat aaaaattaat ccagaaaata aaaaaatcaa gactataaaa
    33661 agtataaatt taagtaatta tttttccgaa aaataccaaa acatagagac cataggtgta
    33721 agttatgcta gcaaatatga ggataagatg tatattttag taaatgtact aaatacaaac
    33781 ataggtgata atagtaattc taaatttcat ttacttgagt ataatcttga agaaaataag
    33841 gaaagcataa tggaattaaa aactgatagc aaaatggctt tagcaaaagc aaagttagaa
    33901 gctaataaat tatatatggt aatgtcgaat gattatgata atagttcaat tacagagtta
    33961 aatttactta cctataatat attagataaa agcttagatg aagataaata tgttttagat
    34021 aatagagaaa aaagaggaat tagaagtatt gaaattgatt caaataaaat cgttgcatat
    34081 acatcaaggc taaactctat attatcttgg gataataaat ttatgctata tataataaat
    34141 aaaaattcta aggaaattgt atatgaagga gaattacaat ttaacagttc aaatagtatg
    34201 ttagaatttg aaataaagta ggtgagttga tgaaagattt aataagatta ttcgaatttg
    34261 aactaaaaag aaatataaag aattatatat ttataataat ttgttgttgt tcttttgtaa
    34321 ttttaaacat agtaaaaaat ttaaatgact ataattacat aatagaaaat gcagttaaaa
    34381 gtgaacagtt aacaaaaatc ggaaatacga tagaaacggt aaaggttaca ggtttctcaa
    34441 gctttagaaa tataatgggt tctacagaat cgtggtttat gtttggtata attgcatgta
    34501 tttgctattc tttttttatt tggtatagag actttaatgg taggagtaaa tctatatata
    34561 cacttataat gctacctaaa aatagaatca atatttatat atctaaatta ttaaatatat
    34621 tatttctagt gtatagctat acagtagtac ttacaatatc tttgtttatt gcaagtaagt
    34681 tgttgcctag acatatgctt ggtaatgtca caaactatgg ttttgtacaa gaaacaatat
    34741 atgagttaaa aatgttactt ccatatagct ttgaaatact atttgtagag tatatatttt
    34801 tattgatagg atttgtatct gtagtattta catcaattct tataaataaa tctatttata
    34861 aagtaagcac tttaataagt tttctatttt tagttataga aattttagtg tttataattt
    34921 ctatagaatt tattataccc tacgaataca gtgatgtatt tactgttcta tattcaagta
    34981 taaacatatt tgtatgtagt cttatatcta ataaactttt gaagcaaaag attgactttt
    35041 aggagggata ttatgaaagc aaaaaatata ggaaaatata caatatgttt tataatagta
    35101 tgttttttaa tgattactat gaccttaata ttgagttatt ttaataagga taaactatct
    35161 gtaaaaactt taaaaggcaa tgtaaaagat atagggagag taagtgtagt atatacacct
    35221 aatataagca aattttctta tgaggaggta attataagta aaaatggagt aagaaataat
    35281 acaaacccaa aatcaagaat tagaaatgat tatttaaata ttgacaaaaa atacagtgac
    35341 tttgttaatg ataaaggaaa agaatttata tataaagatg atttgaatat aggagaagcg
    35401 tatacctctg ttaagtctga tttagtacaa ggaatgaatg ctttaaatga ttgtataaag
    35461 gtttcaaata aaaatttaaa aagtggggta gaagaaaatt ttgatattaa tttaaataag
    35521 tctgatttta aagaaaatag ttggaaaacc ttatttaaca aaatatataa aggtaattta
    35581 tatatggtaa ttagtgaaac taatatttca ggttctaaag tcaataatat ttgtatacta
    35641 aagatagata taaaaaataa gtcttataaa ttattaaata gatttaattt aggattacag
    35701 aatggagaac aacaaaatat caatgaaatt aaattttcta ttggaagtaa attatactta
    35761 gaaatagtaa ataataaaag taaaaatgga tatattgaag gacatgatag ttactctaac
    35821 tttattatat atgatataga agataacact tttaatataa gtaataaatt tatggataat
    35881 ctaaacaaag aaaagaatgc aaatccaaag gagattggct tattaagtaa aactaagcta
    35941 gattatatgg taaaaaataa taaattgaat cttatagtta cggatatgag taattccata
    36001 actaatcttg tttatgatat taattctaat gagattaaat tagaagatta tgagatactt
    36061 gatttaaaag tagattataa tgaagcatca tctggagtta ggaaagttaa gctactggat
    36121 gataagatat attctatttc aggtattaag aacagtatat caggagaatt aaaaggattt
    36181 aaagggattg ttgatgtagt cggaactaag ccagtaaaat ttcaagtatt tgatatgaaa
    36241 cttaaaaaga atatttatga agctgagcta ataaatggag atataagttt acaagaaaag
    36301 ttattttttg ttgcaaatta agtgttagaa ttaattttag aactttaaac ttttatatgt
    36361 atcacagata agtataagta agggagtgtc tcaaaataaa ctttttagct catgagacac
    36421 tttttttata tgaaatcaaa tatattttca ttgtttagat ttattttgat aatgaaaaaa
    36481 agattatctt tattttaaga aagacattta tttataatta tatacaaaaa tattttttaa
    36541 tgtttttgtg tataattata acaatttaat ttatattaat gcacttaaat ttgaaataga
    36601 atgcttatag tggtaaaatt aattattaga atattagaaa taataaataa ataatacatt
    36661 gtacttaaaa gggggagaaa tttaagatga acaaaaaata tattaaagca gggaatttaa
    36721 ttgatggaac cggaaatagt attatgcaaa ataagggtat aattattgat ggagatacta
    36781 tagttgaaat tgaagatata agagatgatt taaatggata tgatgtgtac gattacttag
    36841 ataaaactgt tatgccaggc attatgaatt gtcatgttca cttgacaatg gagccagttg
    36901 gaaatccaaa gatatattat gataatgtat cagatgtaga gcttgtagta aatacgataa
    36961 aacaacttga tgcttatttg gattcaggag taacatatat tagaagctta ggttgtccca
    37021 aatatgtgga tgtacaactt aaaaatctta tagacaaagg gtctatagat ggtcctggta
    37081 tagttacttc aggtccagtt atatgtatga caggagggca tggatattat tttggtattg
    37141 aaagtgatgg agtagatgaa tgtagaaaat cagccagaac agttttaaaa aatggagtag
    37201 attgtgtaaa gataatggca actggaggtg taacaactga tggagttgag ccagggtcac
    37261 cacaattaac tttggaggaa atgaaggctg ctgtagatga agctataaaa gcaggtaaaa
    37321 taactgccac acatgcacaa ggaagaactg gtataaaaaa tgcagtgctt gcaggaatta
    37381 cttctataga acatggtgtt tatttagatg atgaaataat tgatttgatg cttgaaagag
    37441 gaacttactt agttccaact gtggctgcac catattttat tctaaatgca ggaaaagaaa
    37501 gtggaataac tgaagctact cttagaaagt gtgagattgt tgccattcca cacaaagagt
    37561 cattcctaaa agcatataaa aaaggaatta aaattgcagt tggttctgat gcaggaactt
    37621 cttataatga acatggaaaa acatattatg aaatgaaact aatgtcagat tatggtatgg
    37681 ataatatgga tataatagtt gctgctacaa aaacagcatc tgaactttta agaattgata
    37741 aaaattatgg aactctagaa aaaggaaaga aagcagatgt tatagttgta aatggaaatc
    37801 cagtagagaa tatagacgta cttgcagatg tgttagcagt atttaaactt ggtaaaaaag
    37861 ttagataaat agtataaaaa taaaaaagag tgtctaaaga aatttttaaa taattataga
    37921 cactcttttt tattagtaat aattaaatct tttatacttt agaaaataga ttctatttta
    37981 tatttagata taactcttta aaatcattct tatgcaatat aatctataga atctacacat
    38041 acaaagtata ttcttgaatc attagaattt ccaagtacta taacatcatt tttcttacct
    38101 agaacttcaa caccagttag aaccaaacta ccagctacta cagtaacttg attatttata
    38161 tttgacatat aaagattatc taggatacct ttattacaac agcaatcatc acaatcgcag
    38221 ttacaattac attctttgta atgtttttta tcaagatagt aacctaaaga tgctatgaaa
    38281 tcttcataat ctgcaggtgt aatatcaaat gcaacagctt taagattaca caatgatgct
    38341 aaatctacgt ttgctaatgg agtagatgca gcaagtataa aatcaattat agcagcaagt
    38401 attgcatcta atatagcccc aaggtctatc gtaggaggaa taactgcatc aataagtgca
    38461 attaattcag ctactcctgg tatagttcct atagtattaa ttaatccctc aagagttaaa
    38521 gggactggaa taggataaga tactctacca gctatatcta ttaaatcaca gttacaagca
    38581 gaaaatcttt caaaagtacc atcaagtcca gataaattat cttttggagg agctgaaaga
    38641 tctataccta ccaaattagc acctactata aagaaatctg agataaaagc aaattgatta
    38701 aagtttacaa aaggtcttag agcatcatat cttagaagtt ctaatgcttc tctcatactt
    38761 tttttacaac aacattgttt tattttaggt tctttatatt tatttggata attatagtat
    38821 ctatcagcta cttgataatt ttcatagtat ctttcatttg tatttggata atcttcctca
    38881 tattcttgtg taaatctaaa gtcctctcta catttattat tttccactaa atacactcct
    38941 tttatatttt aatttaaatg tatagataat taagcttatc tatatagtaa tattatattt
    39001 ataatgtaaa aaaatgttac aaaagatatt ataaacgaat aaaaaataat aatttgtcag
    39061 ataaacttgt aaatttttat gaataatcca ttctaaaaca aaaaactgtg tataaaaaag
    39121 gtttatatgt tatatttata taaatataac atatgaacga gaaaggagtg gtttgataaa
    39181 tgattgaggt agataaattg tgtaagtctt ttacaagggt tgtaaaagat gataagaata
    39241 aaagttcaat aagaaagcta aagaaagtaa aaactaaaaa agaagaattt tttgctgtaa
    39301 ataatgtttc atttaaagtt atggaaggtg aaattgttgg aatattaggt ccaaatggtg
    39361 caggaaagac tacattactt agaatgttag gtggcatatt aacaccaaca tcaggaagta
    39421 taaatatttc tggatatgat tattcaatag atagaaattc agcaaaaaaa gaaataggtt
    39481 atctctctgg aaatacaaaa ctatatggaa ggctttctcc gagagaactt ctaacaactt
    39541 ttgcaagtct atatgagatg tcaaaagaag atatagaaga atcaattgaa aatattgtaa
    39601 aaataatgga tatgagtgaa tttatagata atagaattga aaatctatca actggtcaga
    39661 ctcaaagaac atctatagct cgttgtttaa tacattctcc aaaagtatat atttttgatg
    39721 agccaacact aggtctggat gttttaagta gtgcatctat tatagatttt atgaagaatg
    39781 aaaaactaag gggaaaaact gttctttact caactcatta tatggaagaa gcagaaactt
    39841 tatgtgacaa gatttttatg attcacaatg ggaaaataat tgcatcagga acaccacaga
    39901 gtttaaaaga ggaatctgga gtaaataatt tgagagatgt attcataaaa cttgccagaa
    39961 aggaggacat ttaaatgaga agtaagattg taaaatacat atttaaaaaa gaaatgttag
    40021 acatattgag agataaaaag actttattta tgatgattgt tgtgccactt cttttatatc
    40081 ctttacttat gttattaatg attcaagtaa tgaatatgtc tgcaagtagt atgaatagta
    40141 aggacattaa tatagctttt aataataaac ctaataaggt gttagtatcc atgattgaag
    40201 atgataattt agaaaaagat actaaaaata cttcaaatga taaaggcaaa ataagagtgt
    40261 tagatgtaga taactataaa aagtcattag aagaaaataa aattgatgct tatataaaga
    40321 tggaagaaaa aaaatcatct ataaattatc aaatatatat aaattcttct caagaaaatt
    40381 cttctaatgc actaaaaaga attgaaactg ttttggataa atataaaaga tttaccatag
    40441 aaaaaacttt atctgaaaaa ggattagatg tacaagctac tttagaacca ataacatata
    40501 gcactgtaga tgttgcaaag acggaagaag tggcaggata ctttttaggt cagatacttc
    40561 catttatatt aataatagga gttttactag gttcaatata tccagcaata gatgttatgg
    40621 ctggagaaaa ggaaagaggt acattagaaa cattatttac actgccaata tcaaacttag
    40681 aactggttat gggaaaatat atggcagttt ctcttagtgc aatagtaaca gcaattttaa
    40741 acattttatc tatgggactg actatggcat ttattttagt tagtggaggt attagtagcc
    40801 aatttggctt tggaaacttt aattatggag acttagtctt accaattata actactttaa
    40861 tttgcatatg tcttttttca atggtagttt cagcaataag tatgtgtgta tgttcattag
    40921 caaaaagttt taaagatgct caaaactaca taacacctct tatgttaatt attatgatac
    40981 catcatatgt ttctatgata ccaaatatag tattagatag agtgacagct gtaatacctg
    41041 tagtaaatat atctttactt ataaaaagtg tattatcttt taaaagcgat ttaaatttaa
    41101 tagccttagt tttagcatca aatgtagcct ttgttatatt ggcaatcata ctactgtcta
    41161 agatgttcaa ttctgaggaa atactttttg gtaatagtaa gagtttttct ttcttagaga
    41221 aaagaagtaa tataaaaaaa gggtctatac caactgtaag tgatggtgtt attttatatg
    41281 cagtaggatt agttctattg atttatgttg gttctttagt tcaaattaaa tttggtatgg
    41341 caggtattat aatgacacaa ttcatgataa tttctttacc attattattt gcatactata
    41401 ttaaagctga ttttaaagag gtatttagct tgacagttcc taaattaaag catgtgtttg
    41461 ggagcattgt tctttggatt ggtggataca tacttattat gattataaca cagctaattt
    41521 tattcttatt tcctcaaaat atggaagttg ctgaaagttt aaataaggct ctttttatca
    41581 aagatagtgt tttactgaat ttactagcaa tagctttatt accagctata tgtgaagaaa
    41641 tgttttttag gggatttata ttttcttcat ttagtaaatc aaaagataaa aataagtcta
    41701 tcaaactcgc tataatatgt agtggggtac tatttggtat tatgcatatg gattttatta
    41761 gaataattcc aacatcaata ttaggtatta tatttgcata cagtgtgtat aaatctggtt
    41821 caatatttgt atcaatgtta ttgcattttt taaataatag tgtagcagtt gtgttaaatc
    41881 attatacaac tggaaatata accaacttat ataaatttgt tgaagttgat ttttcgaact
    41941 taaatgtgct taaatttgcc ttaattcttc taataagtct tatattaatt atgttaggat
    42001 taagagtttt agatagaaag tctttaagaa attaagtata aagttattat atagattaaa
    42061 atatta
//
LOCUS       DAGQVA010000030        40090 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.030, whole genome shotgun sequence.
ACCESSION   DAGQVA010000030 DAGQVA010000000
VERSION     DAGQVA010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40090
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.030"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            205..1056
                     /locus_tag="MIV85_001760"
     CDS             205..1056
                     /locus_tag="MIV85_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBY2961101.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNGLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1189..2802)
                     /gene="ggt"
                     /locus_tag="MIV85_001761"
     CDS             complement(1189..2802)
                     /gene="ggt"
                     /locus_tag="MIV85_001761"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBY2961102.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(3027..4964)
                     /locus_tag="MIV85_001762"
     CDS             complement(3027..4964)
                     /locus_tag="MIV85_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961103.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKIIELIDKDINIEMYYKNRNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4951..5718)
                     /locus_tag="MIV85_001763"
     CDS             complement(4951..5718)
                     /locus_tag="MIV85_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961104.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            6006..6680
                     /locus_tag="MIV85_001764"
     CDS             6006..6680
                     /locus_tag="MIV85_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961105.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6704..7708
                     /locus_tag="MIV85_001765"
     CDS             6704..7708
                     /locus_tag="MIV85_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2961106.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7820..9049
                     /locus_tag="MIV85_001766"
     CDS             7820..9049
                     /locus_tag="MIV85_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBY2961107.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            9057..9731
                     /locus_tag="MIV85_001767"
     CDS             9057..9731
                     /locus_tag="MIV85_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961108.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9734..10966
                     /locus_tag="MIV85_001768"
     CDS             9734..10966
                     /locus_tag="MIV85_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961109.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11252..12517)
                     /locus_tag="MIV85_001769"
     CDS             complement(11252..12517)
                     /locus_tag="MIV85_001769"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBY2961110.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12570..13718)
                     /locus_tag="MIV85_001770"
     CDS             complement(12570..13718)
                     /locus_tag="MIV85_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBY2961111.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNKVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13818..14363)
                     /locus_tag="MIV85_001771"
     CDS             complement(13818..14363)
                     /locus_tag="MIV85_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBY2961112.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14586..15530)
                     /locus_tag="MIV85_001772"
     CDS             complement(14586..15530)
                     /locus_tag="MIV85_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBY2961113.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            15916..16797
                     /locus_tag="MIV85_001773"
     CDS             15916..16797
                     /locus_tag="MIV85_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBY2961114.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(16858..18066)
                     /locus_tag="MIV85_001774"
     CDS             complement(16858..18066)
                     /locus_tag="MIV85_001774"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBY2961115.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(18139..18391)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18543..19532)
                     /locus_tag="MIV85_001775"
     CDS             complement(18543..19532)
                     /locus_tag="MIV85_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBY2961116.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            19684..20124
                     /locus_tag="MIV85_001776"
     CDS             19684..20124
                     /locus_tag="MIV85_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2961117.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            20451..20678
                     /locus_tag="MIV85_001777"
     CDS             20451..20678
                     /locus_tag="MIV85_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBY2961118.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            20704..22824
                     /gene="feoB"
                     /locus_tag="MIV85_001778"
     CDS             20704..22824
                     /gene="feoB"
                     /locus_tag="MIV85_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBY2961119.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(22957..23775)
                     /locus_tag="MIV85_001779"
     CDS             complement(22957..23775)
                     /locus_tag="MIV85_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2961120.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            23982..24266
                     /locus_tag="MIV85_001780"
     CDS             23982..24266
                     /locus_tag="MIV85_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961121.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   24424..24981
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=24491..24519
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(25640..27733)
                     /locus_tag="MIV85_001781"
     CDS             complement(25640..27733)
                     /locus_tag="MIV85_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2961122.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
     gene            28386..29309
                     /locus_tag="MIV85_001782"
     CDS             28386..29309
                     /locus_tag="MIV85_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBY2961123.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            29284..30111
                     /gene="panB"
                     /locus_tag="MIV85_001783"
     CDS             29284..30111
                     /gene="panB"
                     /locus_tag="MIV85_001783"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBY2961124.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGTFPQEKHSFSINESELEKLY"
     gene            30130..30978
                     /locus_tag="MIV85_001784"
     CDS             30130..30978
                     /locus_tag="MIV85_001784"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBY2961125.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            31389..31571
                     /locus_tag="MIV85_001785"
     CDS             31389..31571
                     /locus_tag="MIV85_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961126.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            32403..33317
                     /locus_tag="MIV85_001786"
     CDS             32403..33317
                     /locus_tag="MIV85_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBY2961127.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRYYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            33707..34354
                     /locus_tag="MIV85_001787"
     CDS             33707..34354
                     /locus_tag="MIV85_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBY2961128.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(34521..35090)
                     /locus_tag="MIV85_001788"
     CDS             complement(34521..35090)
                     /locus_tag="MIV85_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBY2961129.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(35095..35994)
                     /locus_tag="MIV85_001789"
     CDS             complement(35095..35994)
                     /locus_tag="MIV85_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2961130.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGILLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(36005..36154)
                     /locus_tag="MIV85_001790"
     CDS             complement(36005..36154)
                     /locus_tag="MIV85_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961131.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(36147..36731)
                     /locus_tag="MIV85_001791"
     CDS             complement(36147..36731)
                     /locus_tag="MIV85_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBY2961132.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            37120..38445
                     /gene="cdeA"
                     /locus_tag="MIV85_001792"
     CDS             37120..38445
                     /gene="cdeA"
                     /locus_tag="MIV85_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBY2961133.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(38540..39334)
                     /locus_tag="MIV85_001793"
     CDS             complement(38540..39334)
                     /locus_tag="MIV85_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961134.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(39335..>40090)
                     /locus_tag="MIV85_001794"
     CDS             complement(39335..>40090)
                     /locus_tag="MIV85_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961135.1"
                     /translation="AGKTTLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREK
                     EFYSPDFKVGQIFEFSSSFYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNII
                     GICSNSAITIFDEPTIGLDAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHV
                     IILNEGKIIIDEEIDVIKQKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDF
                     SENDEKILKNSNIDVGYIGLQDMFVNMTKKEEL"
BASE COUNT        14339 a         5888 c         4917 g        14946 t
ORIGIN      
        1 tttcatattg tataaaatat actcttattt tattatatat ctaaaatttt caatattcat
       61 taattatttg aatttttata taaaattttt acaatttcta aagatttatt tacttatgta
      121 ataaattata ataatattag tttataaagt taataattaa tataaattaa aataaagata
      181 atataaacac aggaggtaca ttctttgaaa aacattattt cagcaaaaga acttatatca
      241 aaactagaaa aaaatgataa tctagttgta atagattgca gatttgatct tatcaataga
      301 acttatggta ttgattctta taaaaaagga cacatcaaag gcagctttat cttagatata
      361 gacaaggatt tatcatctcc tacaaaagaa catggtggta aaaatccttt acaagaccct
      421 ttaatactaa aagaaaaatt agaaaaaatg ggtgttgata acgacactac gattgtaact
      481 tatgatgatg gagatttaaa tggagcttgc agattatttt tccaattaaa acatttgggg
      541 cttaaaaatg tctatgtact ggatggggga ataacatctt tcgtaaagga aggtggagaa
      601 ttggaagaga aagtgaatat accaagttgt acaggtaagg aaattagacc aaatataaac
      661 aatggtttag ttgttccaat ggaatatgtt aagtctaaat tatacaaaaa agatactgta
      721 ataatagatt gccgtgctaa tgagagatac cagggtttag ttgaacctgc ttactcaaaa
      781 gctggtcata taccaagtgc aaaaaattat ttttgtaagg atttaataaa aagtgacttt
      841 gaaaatggct cacttaaaga tatagaattt ttaaaaaaat tctttaaaga tttaaataat
      901 tatgatgaag taattttatc ttgtggttca gggatatctg cttgtgttaa cagtcttgct
      961 cttagagaac tggatatacc tcacaagatt tatattggta gctttagtga ctggattagt
     1021 tatgatgaca atgaaatcaa aactggtcaa gaataaggct cataatctat ataaaatcag
     1081 catatgatag cttaaatttt gtaaaggcgt cagtcattgt agactttcgc ctttactaat
     1141 tatttcatat actctttaaa tttattatat atattttagt tgataatatt aataaactgc
     1201 aatatgacca tcacatcttg attccgtccc acaaatataa ctttcctgtt ctgttttaaa
     1261 tattatttga cctcgtccca tgtcgacagt atcatgaatt acttttattt catgaccctt
     1321 ttcaattaat gaatctatta tgtgctttgg catctctggt tcaacttcta tttcctttcc
     1381 ttttatccac tgccatcttg gagcatctag cgcctcttgt ggatttaatc caaaatcaat
     1441 catatttgtt aacacttgaa tatgtccttg tggttgcata aaagctccca ttacaccaaa
     1501 tggacctatt gctttatctt ctttacctaa aaatccaggt attatagtat gataaggttt
     1561 tttaaatggt tttactacat tgtggtgttt agggtctaaa ttaaaattat ttcctctact
     1621 atgtaaagca atcccagttc ttggtatcac aattcctgaa ccaaaattta tgtaattgct
     1681 ctgtatatat gaaaccatat ttccatcctt atctgcagta caaaggtata ctgtaccacc
     1741 acaatatggc tctcctgcag ttggatacaa agcctcttta ttgtcaatca ataaacttct
     1801 ttttttagca tactcttggc ttagtaattc ctgaatcttt accttcatat gctctatatc
     1861 agttacatat gttttagaat ctgcaaaagc taattttaaa ctctctataa ttttatgtat
     1921 gtcttctaca ttttctatat ttccttctaa ttccaattct tttaatatgt taagtgccat
     1981 taaaactgtt attccatgac catttggtgg gatttcaaat attttatatc ccttatattc
     2041 tgtacttata ggttctaccc atgttggata aaaacactct aagtcactct ttcttatagc
     2101 cccattaaat tttttagaat attcatctat tttatcagca agtcttcctc tataaaagct
     2161 ttcagcctga gtatttgcta tctcttctaa tgtacttgcc tgttcttcac atataaatat
     2221 atctccagcc tctggagctt taccatcttt agaaaatgta tcaaaccatg gtttgaactc
     2281 ttctccaata agttcttttt catagagttc atatgatttt ttccatacct tagctacatt
     2341 aggagatact acgtatccct ctcttgcata gtttatcgct ggagataagc attccattaa
     2401 gctaagttta ccatattttt tatttaattc tgaccaagct gctggtattc caggtacagt
     2461 tactgctcca aacccatatt ttggcatttc tttcatatta ttataatttt ttaattccat
     2521 attttctgga gcaaagccac tagaatttaa accatacaat cgtttttctt cctctatcca
     2581 aacaagggca tatgcatctc ctccaatccc attgcttgta ggttctacta ctgctaatgt
     2641 ggcggctgtt gcaactgctg catcaacagc atttccaccc ttttttagta tttcaagtcc
     2701 agcttgagat gctaatggtg ttgatgttgc aactgctcca tttttagcat acacgacatt
     2761 tcttattgat gagtatttat gttggtaggc attaaacttc ataaatttca gctcctcgtc
     2821 attttttatt tgatattctg cttagattta ttatataaca tcaattaatg taactgatac
     2881 aaaatgatat aaaatataga ctttttccta actttaattt tatctttaaa taaatatctt
     2941 aaactcaatt ctagtatttt ctatctgcac ttaaataagt tattttattc aaaacatata
     3001 tctaattctt ttaacttaaa aataatttat tcttttatca tgtttagagc atattttaaa
     3061 gttaaaaaat aatatataaa atatcctata aaataaatga ctagagttat gataattggt
     3121 acaagtaatg accttggtat aaacttttgt gctatagaca tagcaaataa attatgaact
     3181 gtacctacaa ctaatggcat taaaaatata acttttaact gttttgatat tattttctca
     3241 atatctttat tatttgctcc aagttttatt aacataatat atctttcctt atcatcatat
     3301 atatttgata attgtttaaa taagattata ctacctgtac ataaaagaaa tactacagac
     3361 aaaaatatgc ctataaacag cattagacca cttaatttta tcaagttatc ataactttca
     3421 atacttgatg taaaattaaa aggataagta aatttcatat tttcacttac tatatttttt
     3481 aattttaaag tcaaatccag ttcttttttt tcatttttta tatcaattaa tcttattaat
     3541 ctagaatttc catgtaattt taactgatta aatacgtcat cttttactac aattaaatca
     3601 aacgtagctt gtgaatttat ttctggctcc aagatgcttt tttgtacttt aaacagattt
     3661 atatcatact catttgcatc tttaatatgc aagtttattt tttcaatctc aaagtcttta
     3721 aaaaatattt ttttgtatga atcagaaaca tagtacacag attcctttga agttaattct
     3781 tcataattgt tattctgata ttgtcttaat tttttaaaat cactttctct aataatatct
     3841 acagacgttc tatcttctat ataactattt cgatttttat aatacatttc aatatttata
     3901 tctttgtcta taagttctat tattttatca aagattatct tattatcttt tttatattta
     3961 tataataatt tgtcaatttc gttatttaca taagaatttc ctaaatttat ggtataactg
     4021 tatttataat tttcacttat gttcctatct atatcgtaat aaagtgatat ggtaaaccct
     4081 agcatagtta cacttgtagc tattaatatt gctattacag ccaatacact actattgctc
     4141 tttaatttaa atccaagttc agaaaatgca attaaattct gtcccttata ataaaaactt
     4201 tttctcttct taacagcatc aataatcata tacatagttg atgaaaaaaa taaaaaagtt
     4261 ccaggtatta ttgtaactaa tataaaaact gaaagcataa tattttcagc aataaaataa
     4321 ctaattgaca ttaaataaga aatagctatt aataaaacac caagtacaca ttttaacttt
     4381 ataaattttt taaacttata cttttctgga tatttattaa ataactctat aattctctta
     4441 tttctgataa ctatagtatt tcttattcca ataactatga atattattaa aaataccgct
     4501 agtgtctgaa ctaaggcctt tatacttaag ttcatattta ctactatcat ttcattcatt
     4561 aattttacaa gcatcatagt cataagcttt gaaaataaca gtcctaaaaa tatacctatt
     4621 agtattgcaa ctatacccat caaaaaagtt tcatataaaa atatttttcc tatctgattt
     4681 ttcctcattc caagtaaact ataagttcct acttctcgcc tacgtctatt gaaaaaaaat
     4741 gagtttgaat aatatataaa taaaaataca aataccacta ttacaattga acttgtatta
     4801 atactcatcc tagttttctc tccaagtgaa ctcaacgctt cattatactc tatagattta
     4861 aaactaaaaa atacaaatac actaaataca attgaaataa agtacattaa ataattaaaa
     4921 aaactattct ttacattttg cattgcaatt ctaaataaag tcatttttat taactcctcc
     4981 aattaaggaa actgtattta ctattttatt atagaactct ctgttacttt ctccctttac
     5041 aatttctgtg aatattattc catcctttat aaagagtatt ctattgcaaa aactcgcact
     5101 tatagcatca tgagttacca tcaatattgt tttattgctg tctttgttta attttaatag
     5161 acaattcaac aaatccctag cagatttaga atctaatgct cctgtaggct catctgcaag
     5221 tactaatgat ggttttgttg ctatagctct acatacagct cctctttgct tttgtccacc
     5281 agaaacttcg ccagggtatt tatctaatat agattctata tttaattctt ttgaaatctc
     5341 ttttattcta ttttctatta ctgatactct ttcatttttt aaagaaagag gcaacattat
     5401 attttctttt attgtaagtg tatccaaaag attagaatct tgaaatacaa agcctagatt
     5461 atcacgtcta aaatctgcca attcattttg cttcatttta atagtattct ttccatttat
     5521 ataaatatct cctgatgaag gtaaatctat tgtagaaata atatttaaaa gtgttgattt
     5581 accagcaccg gaagacccca taataccaac aaattctcct ttataaacct tgaaagttat
     5641 tcctcttaga gcttcatgtt ttgaaccttt tcttccatac tcctttttta tattttcaac
     5701 agataatatt tcttccatag ttaataatca cctttcatca caattagtta tttatcaatt
     5761 ctcacaaata tattatatat attaaaatgg cttttaaaca tttaattata ttaatttaag
     5821 gttacatttt cgtaagtatt aattatattt cttcaaattt attgcaatta tgtttaaaat
     5881 ataatttatc aagtaaaata tagttatatt aatataatta ttttaggtaa taaggtagaa
     5941 atattttaat ttatcaagta gaatatagtt atgttaatat aactattttg aattaggagg
     6001 taagaatgtt taaaataatg gtagttgaag atgacgtctc attgaaaaat atcatagcaa
     6061 agtgtcttac taaatgggga catgatgttc atcaaataga aaatcttgaa aatataatag
     6121 aagagttcaa aaactataac ccagaattag ttttattgga cataaacctt ccattttatg
     6181 atggttttca ttggtgtaat gaaataagaa aaatttcaaa agttcctata atttttattt
     6241 cttcaagaaa ttctaatatg gatgtaataa tgggtgtaaa tttaggtgca gatgattata
     6301 tacaaaaacc tttttctgta gatgtcttag tagctaaagt taatgccctt ttaagaagaa
     6361 cttataattt tgttgataat aactcaaatc agattattca caatggtgtt actttagatt
     6421 tatcaactgc aacaataaac tatgaagata atactattga actaacaaaa aatgaaatca
     6481 aaattctcca tgagcttatg aaatataagg ggcagatagt aagtaggaat aaactcatga
     6541 aaaaattatg ggataatgat tggtttgtag atgataatac attaactgtc aatgtaaata
     6601 gaatacgctc aaaattaaat gaaattggtt tagaagattt tatagaaaca aaaagaggat
     6661 tgggttatat aatcagttaa aacaattcta agtaggtgaa tttatgagct ttaaagattt
     6721 tctcaaggat aaactaggtt ttttagtata caattttact ttcttaattt ttacagtatc
     6781 agttattata ttttctcctg tagatgtttt tctgactgat actattttat atatattagt
     6841 tgtaaatgtt gtgtttttat ttttatatct atttattagc tacatcaaga agaacaaatt
     6901 tttagataag ataaaaaatg atacattcaa aattaatatg aatgatatag aattagctag
     6961 atgtaaaaat gaagaaaaaa tatacttgaa cattattaaa aatcatcaat atcaatgtaa
     7021 taacataata aataataata tcgagaaatt tgaagaaaac aaagagattt taaatatgtg
     7081 ggtacatgat gtaaagatac ctatagctat aataaaactc attcttgaac aaaatgaaaa
     7141 tttaattgat gaaaaaattt cagatgacat agatagtgaa atatttagaa ttgaaaactc
     7201 cgttgaaaaa attttatatt tatcaagact cgaagatttt cataaggatt ttttaattca
     7261 agaggtaaat attgaaaaaa tcattagaaa tattataaaa aaatactcaa aatattttat
     7321 ttcaaaaaaa attattttag acttaaataa tttgaatttt aaggttttat ctgatgaaaa
     7381 atggctatac ttcatattcg agcaattatt gagtaattcc ctaaaatact cctcattagg
     7441 agataatata tctatctatt gcaaaagaac caaaaattat ttacaattaa gagtggaaga
     7501 tactggttgt ggtataaaaa aggaagattt aaatcgaata ttcaataagg gatttacagg
     7561 taataatgga agaaacaatt ctaaatctac aggtcttggg ctttatttag taaaagaact
     7621 ttgtgataag cttggtcata aaattgatgt agattcagag tacaaccaat atacaaaatt
     7681 tactattaca ttcaaatgtg atttatagta tcttattatt gatagtttat tttcattaac
     7741 ttatattcaa cttcttatag taattctata tgtacatccc agtatataat taagtagttt
     7801 ttataaaaag gaggaagaca tgtcttttct aaaaaaattt aaaaataaaa gatttagaaa
     7861 taacagtttt aaaagtaaca actttagaaa tagcagtttt ggaagtagtg gcttcaagtc
     7921 taaaaataaa ggttttaaaa acaatccctt taaaaataag agattcaaaa tatatgcagg
     7981 aatagcagta atcatacttt taattctagg agttcttgct tatgttgatt cgaaaaacac
     8041 tgaattacaa gctaatgaaa attttatcga aacatatact attcctgaaa atgaaaaaat
     8101 atttataaat gggatggttg ttcctaagca aactaaggac ttcaatatat ctggagatta
     8161 tgagttaagt gatgttaatg ttacaaatgg tcaaaaagta aatcaaggag accttctttt
     8221 tactgctaaa aatccaacta taatagcaga aatagatagt ttaaaatcac aacttagtca
     8281 atacaaaaaa caaaaaatat cactttctga tattgctgaa aataaagatg ctattgcttc
     8341 tataaatgca cagataactg ctttaaactc tcagatagct tctctggata aaaaagctta
     8401 tgacagagtt actgctcctt ttgatggcac agtatacttg aatgaccaaa ctggaaatcc
     8461 agaccaacca gtttcattta tgactattca aggtctagag ttttatatga aaggacaagc
     8521 aagtgaacaa gatttaccta aaatgaagat tgaccaaatg gtcaatatac tagttttttc
     8581 aactgaccaa aagcttactg gtagaataag ttttatatct gataaaccat ctactccaaa
     8641 tactgaaatg ggagctcagc agaatacact atcttattat gatataaaca tagcatttga
     8701 taatcaagaa ggattagtaa atggattcca tcttcaagca tcacttgaag tagctaattc
     8761 aagctttaaa ataccagcat cttgtgtact taaagacaac aaacactcat atgtatttaa
     8821 ggatttagat ggtatattga aaaagcaaat tgtagatgta gcaagtcaaa atgatgattt
     8881 tgctgtagtt agaggcggtc ttgaacaagg cgatataata ataaaacacc ctactaaaga
     8941 aatgaaagaa ggagacccag ttcaaggcga tggcgtaact gctggttcta ataatggaga
     9001 tactactcca aacaaaaaag tagaagaagt tactatggat gtgaattaat ttacatatgt
     9061 taattaaatt agaaaatatt caaaaatatt acaaagtagg gaaagatgaa ttacatgttt
     9121 taaaatcctt aaatttagaa attgaatctg gagaatttgt catgataatg ggtaagtctg
     9181 gtagtggtaa aactacttta cttaatatct taggttttct agatgtattt gatgaaggaa
     9241 gatatatatt tgatggaaca gatgtaacta atttgagtga aaatgaacgt tctgttttta
     9301 gaaatattaa tattggattt gttttccaac aatttaattt aatagaaact ctaaatgtat
     9361 atcaaaatgt agagttgcct ctaatttaca ataaagcact aaaaaaatct aatagagaag
     9421 aaattgttaa agataaatta agttctgttg ggcttttgga caagcttaag cagaaaccac
     9481 ttcaattatc tggtggtcaa caacagcgtg tagccattgc acgttgccta gcaaatgacc
     9541 ctcagataat ctttgctgac gaaccgactg gggcattaga tagtgaaact agcagagaaa
     9601 ttatggagct tttaacaagg ctcaacaaac aaggtaagac tataataatg gttacacatg
     9661 atcaagattt aactaagtat gcaactaagg ttatacgact taaagatggt gtgtttactt
     9721 cggaggtgta atcatgagtt tattaaaaaa ttctttggcc aatttaaaag gtcacaagct
     9781 tcgtgtattt gtagctttac tctggattat aataggaata acttcagtaa tacttgttag
     9841 ttctataggt aatggatttc aaaaagaaat taagaaatct gtaaacaatg taaaccctaa
     9901 taaaactact atttcgtttg aatcagccga taacacaggt cttactgatg atatgagtat
     9961 ttttttaaaa ccctttaatg caaaagattt agaagaatta tcatttgttg aaggagtaga
    10021 aagaatagct ccttcaagag atgggtttaa ccttgattca gtttactctt cacaagcatc
    10081 ttttgataaa aaaactacgt atgttgatgt tggaccagta aaaaaagatt ctaaaataaa
    10141 tttaatttgt ggtagagatt tttctttaga tgatgaaaaa agaaaagtaa ttttacttac
    10201 attacaaagt acaagtgaaa tttttgaaaa tccagaagat gccttaggtc atggtatcaa
    10261 cataaatgga actatatttg aaataatagg ggtattagat gattctcagc aaaaccaagc
    10321 tggaggattc tttggaggtt accaagatat gcaatttact acttccctag tacctaaaaa
    10381 ggcttttgac actttaatga gtcaaaattc ttattcaaat gaaatttacc agttagactt
    10441 agtttcttct aaaggctata atgtaaatga agttgcaaac aatgttatag ctaaattata
    10501 tgagatgcac cctggtatca atggttctta tactacacca gacccaactg aacagacagc
    10561 ttatcttgaa agcattaatt ccaatgtaaa caaatatgta tctataataa ctgtagttgc
    10621 aatgtttgtt ggtggtattg gtgtaatgaa tataatgtat gtatctgtta tggaaagaca
    10681 aagagaaatt ggtataagac gtgctattgg agcaaaacct aggtctatat tatttcaatt
    10741 tttagttgaa gctgttttta taacagtatg tggtggaatt ttaggaacta tagttggatt
    10801 tgctgctact aactatgttt ctaaatatat aggttttgaa gctataccta gcttaaatag
    10861 cttattttat gcaattgtag ctactatatt gactggagtt gtatttggtc tgattccagc
    10921 ctttaaagct tctaaactag accctataaa ggcaatttat aagtagaaat tgtataaaga
    10981 ttttcgattt ttagattagt ttatataaaa catacttaaa tatataacgc actattatat
    11041 atgatagatt aggaacttaa tctttccaaa tataatagtg cgttctttca taaaaaggat
    11101 tctcttcctt actatatcta aattaccaag atgttatgtt ctaattgttc aaactaatac
    11161 ttccaatttt gattaatcaa tctcattctc ctaatataca atcttttact ttcaatcatt
    11221 gtacactccg ccttaaaaaa ataatcttaa attaggcgtt atatacaatc tccccattac
    11281 atattgtata attaaccttt ccatataaag atttaccttt aaatggtgaa ttatcagctt
    11341 tagaaacaaa gctttcaact gtccattctt cttctggatt gaatataaca atgtctgcta
    11401 cagccccttc ttctataaat ccaatattta aattgtacaa ttttgcagga tttatagaca
    11461 ttttttctat taactgcatc atactaagat gatttttatg caccaaattt gttattccaa
    11521 gagctaaaga agtttcaagc ccaataattc cacttggagc ttttataaac tctctatctt
    11581 tttcttcttt actatgaggt gcatggtctg ttgctattat ttcaatagta ccatcattta
    11641 atccctctat aatcttatct ctgtcccatt tacttcttag aggtggattc atttttgcat
    11701 ttgttccaaa ctccaataca tcttcctcag tcaatgtaaa gtgatgtggt gaagcttctg
    11761 caactacatt tgcacctaag tattttgcaa atctaaccat atcaacagat acacctgaac
    11821 ttatatgttg tatatcaact ttagcaccag tctttagtgc caacatacaa tctctggcta
    11881 ccataacatc ttctgctaca cttgatgcac cttttaatcc aagttctgaa gctacctttc
    11941 ctgcatttac acctggattt ccaactaaag aagggtcttc ttcatgaaaa ctaagtggta
    12001 catccaactc ttttgcctta atcattgcct ccataattag attgctatcc attaaaggta
    12061 atccatcatc agtaaaccct ggtacaccag cttttttaag agcttccata tcaactaact
    12121 ctttaccttc aaaaccttta gttatagctg ctgcttgtaa aacatttata catgcatttt
    12181 ttgacttttc tttaacataa ttaaaagtat cttcattatc tacaatagga ttagtatttg
    12241 ccatacatat aacagttgta aatccacctc tagcagcaga tttagctcca ctttctatat
    12301 cttctttata tgtaaaccca gggtctctaa agtgtacatg tacatccact aaacctggag
    12361 caactacatt accactagca tctattattt tttcatattc atcactttca tcaaacttgc
    12421 ctattttata aattttattt tcttttataa ttaagtcaat attctcatct ctttgacttt
    12481 tagggtctat tactctacca tttttaatta aaatcatatt atttctcctt tatattttta
    12541 atttatatag actcatataa tattatacat tattttacat acttaaatac aaaattacgt
    12601 ttgacatcaa tagccttttt aggacaaagt tcatggcaac agtaacatct tatacattta
    12661 cttaagtcta taatagcacc cttagtccct atctctatag tggatgcagg acaagcttcc
    12721 ttgcattttc cacattttat gcaatcttga aatcttacca caggctttgg tgttataagc
    12781 tttgaaatag gttcatttaa aaattttggt agctttacgg aaaacaatct taaatcttta
    12841 cttacatttg gaatcttgta attttttata attaaatctt ttatatcttc acctaaaatt
    12901 tcaatatctg aaaaatcttc ttgtatatat cctctcttaa tagcacctct aattgtagca
    12961 actttatttg gaagtaaact tataatctta catgcaacaa catctatagc atatggattt
    13021 tgtgatgcta ataaaactcc tatttctcga gtagtaccag ctgaaggtcc atcaccttcc
    13081 atacctacta taccatccat aattgtcaat gttggtttta tataatcaca aatatctaaa
    13141 agtacatttt cgcaaaacaa ctcttctgta ggaaatctat aatgtatctc tgcttttttc
    13201 aatccagcta tgcatccata taagtttttt gtaccaccag taaaagttgc cattatatga
    13261 gtctttaatt tacaaagatt tattatataa tctgaatcta ctattggttt aataatatcc
    13321 atatatttta gaacatgtgc tttttcacta tgtatcttaa catctgaaac atcataattt
    13381 aacttaatgc ccagttcatt tgctacttct tcaattccag atgccttata aatgctctta
    13441 agagaacttt gattatatgg accaccaggg ctatctgcta ttgtaatatc acaatttaac
    13501 tctaaaagtt tttcacatac aacttttaca accataggat gtgtagttgt agcttcttca
    13561 ggcttttttt tcattaataa atttggtttt ataagtactt tgcttccttt tttaacaaac
    13621 ttatctatac caccaatatc ctctaaattt ttttcaatag ataactttac ttcttcataa
    13681 ttgtaagttt tacaactcct aacagatacc gacttcatat tatctccatc cttctatcac
    13741 aacagtttat ttatataatt taaaaaagga gaaaccaaag tttctccttt taatctatgt
    13801 tttaattgtt ttaattatta ttttccaaaa tgtctgttta ataatcctaa gaatgcttta
    13861 ccatgtctag cttcgtcttt acacatttca tgtactgtat catgtatagc atctaatcct
    13921 aattctttag ctctcttagc taattttaat tttccatcag ttgcaccata ctcagcatca
    13981 actctaactc ttaagttttc ttttgtatct gcaactacaa cttctccaag aagttctgca
    14041 aatttagcag catgttcagc ctcttcaaaa gctattctct tatacgcttc agctacttct
    14101 ggataacctt ctctatcagc ttgtctactc attgctaaat acattcctac ttctgtacac
    14161 tcaccagtaa agttagctct taatccttcg attatttctg catctacacc ttgagctact
    14221 cctattctat gttcatcagc ccaaaccatt tcgcctttca tttcttcaaa tttatcagct
    14281 ccaactttac atactggaca ttgtgctggt gcagcatctc cttcatgtat atatccacat
    14341 actgtacaaa caaatttttt cataattaat ttcctcccaa ttttatataa ttaaattttt
    14401 atttttaagt ttaataactt gctacaagaa tatatatacc ccagacttta tagcttaaac
    14461 actaaaaata aaatttattt cctaattaat tttatcactt tgaaacacca gtatcaacca
    14521 agttttgatg tcaaatttct acataataca taatttattt gattaattag gaaatagttg
    14581 tcatattaaa tactttctaa tgaagactcc tctgaatctt taagtttcac ttttttgctc
    14641 tttaaaaaag ataatttagt ttctgcagtt atgattgcaa caaatatcaa gatactacca
    14701 ataaccaatt ttgctgtaat aagctccttt aaaattatta tagaaaatat tgtaccaaat
    14761 acagcctctg tggataatat tatagctgtt ctagttccat caactctttt ttgacatata
    14821 gtctgaaata aaaatccaat tgtagtacta aatacagcta gatacatagt tcccatgtaa
    14881 ccagataatt cagcttccat ctttaattga cctgcaaatg tttgaactac aacagacatt
    14941 aaaaacgcta ctgtaaattg aatagctgtc aatgccattg ggttgttatc ttttgcaaac
    15001 tcacttgtaa agaatatatg aaatgcaaat ccgaatgaac atataagtgt tagaaaatct
    15061 ccaaaattaa tagagaaatc agcttctaaa gaaagtatcc caattcctat aagagctacc
    15121 aaactactta ttattcctat tttatcaagt tttcttctat aaagtataaa tcctatgaat
    15181 ggaactatta caacattagc tgctgttata aacgcatttt tagatggtgt agtgtacata
    15241 agtccaatag tttgtactgt gaatgctaga aataaaaata ttcctaaaat ccctcctgct
    15301 tttaataatt ttttacccat attggcacga atctgtttaa aaaacagtaa attcataatt
    15361 atagctgcca agaaaaatct taaagttatg atttgtagag gtgtaagccc accgtctaat
    15421 gcaaattggg ttgctacaaa gccacttccc catataattg ctataaatat tagtcctatt
    15481 tctccaaagt attttttcaa taaagctccc tcctttttat ttttttgcaa aattataaac
    15541 cccctaaaca gcaagagagt ttttctataa gcattactat aaattaatat agtaaatttt
    15601 ttcagtattt taaatctaaa tttacataca ttttgagctc aaatttatat ccactattta
    15661 acagtaatat attaatcatt ttttgtaaac acctttttaa taaattttta tattttttat
    15721 atttttttac ctatactaaa tttttttata gatattttta atatatatga tactttaata
    15781 ttatgcaaat aatgtcatat aagttacact ttagttatct tagttacaac tttgtcggtt
    15841 tactttttct actttcttcg atataattat aatatatttt tgatacaatt cgacaaaagg
    15901 gggaatgctg taattatggt aaaaaaaaga aaaaagaaaa ctgttacact tactatactt
    15961 gttgtaatag ttattggtat tttttctatg gcatgggcgg acatgtctag aaaaaaagaa
    16021 atgaaagaaa ctcaagaaag acttaaagct gaaagattag aaaaagaaag aattgaaaaa
    16081 gaaaaaaatg aacctattat tggtgcaaaa aaagaagctg taaaagaata tggatatgac
    16141 gcaaaaatag tttgggacaa acttaacaaa tacgactatt caaacaatgg agaaaagata
    16201 gtctttctta catttgatga tggaccatct actactaata ctccacaagt tctagatatc
    16261 ttgaaaagac atggtgttag aggaactttc tttattaagg gtgattctct tgaaagaaaa
    16321 ggagctaatg aaattttaaa aagaacattt gacgaaggaa atgcaatagc ccatcactct
    16381 tatactcatg actataaaaa actatatcct aacagaagcc taaatctcga tacattcgta
    16441 aatgaactta acaaaactga tgaagctatg aaaaaagtct taggaaagaa tttttcctca
    16501 aatgtagtta gatgcccagg cgggtacatg tcatggaaaa atatggaacc tctaggaaac
    16561 tacttaaaag agaaaaacat ggcatcaatt gattggaacg ctttaaatgc tgatgcagaa
    16621 ggtaaaaaga aaaatgcaca agaattattt gaacatgcaa agaaatcttc tgaaggcaaa
    16681 gaaatggttg ttcttttaat gcatgatact tatggaaaac aagaaacagt aaatgcattg
    16741 gaccaaatta taacatattt taaagacaat ggttatcaat ttaaaatttt aatataataa
    16801 aaaagcaagt ttattgaatg tacattttat actcaataga cttgctttta ctttactcta
    16861 ttttactagc tcgattttta caaatttttt ctttcctatt tgaacaacta attcactctc
    16921 ttttacaata gtgcttaaat cctctacttt ttcaccattt acctttactc caccttgaga
    16981 agctaatctt ctaacttcac tcttactctt aacaatctca ttagaaacta gtacttcgat
    17041 taagtcaaat ccatcttcct taacttgaat tgtttgtata tcttcaggta tttgaccttt
    17101 ttggaataca gatttaaatc tttcttcagc ttctttagca gattcttctc catggtataa
    17161 tgttactatt tctcttgcta agttcatctt tatatctctt ggatttactg aaccctcttt
    17221 caactgagat tctattttat taacttcatc aggatgaaca tctgtcacta aattgtagta
    17281 tttaattata agttcatcag gaatttccat agatttttgg tacattattc ccgcttcttc
    17341 atctattcca atatagttac ctaaactctt actcattttt tctttaccat ctaatccttc
    17401 tattaaaggc atcattatta ctatttgaga ctccatacca aattctcttt gtaatgatct
    17461 tcccattagt aaattgaatc tttggtcagt tccaccaagt tctatatcag cttctaatgc
    17521 tatagagtca tatgcttgca ttaatgggta gaagaactca tgtactgata ttggcatttg
    17581 tccttcatat ctctttttaa aatcttctct ttctaacatt ctcgcaacag taatagttgc
    17641 tgctaatttt attacatctt caaaatttaa cttagctaac cactcgctat taaatcttac
    17701 aatagttttt tctttatcta aaactttgaa aatttgttct tcataagttt ttgcatttgc
    17761 aagaacttgc tctgttgtta aagcttttct agctttagat tttccagttg ggtctccaat
    17821 ttttcctgta aaatctccaa ttattattac tatttgatga cctaaatctt gtaattgttt
    17881 catctttcta agaactactg tatgccctaa atgtatatct ggagcacttg ggtctagacc
    17941 caattttact atcataggct ttccttcttt ttctgattta ataagctttt cccttaactc
    18001 tttctcatct attaaatcat ctacaccttt cataattatt cgcatttgct cgtctatcga
    18061 tttcattttt cattcctcct aaaatattta tataatctat aatttttatt tttataataa
    18121 aaaaagcttt catcctctta aaaggacgaa agcattgctt acgtgttacc accttagttc
    18181 atcaatatct cacgatatta atctcttaga gtacaattac atatactcgt gtactataac
    18241 gtgtactaat ccgatatctc ttaatggttg ttatctttca gagatagtgc tctgagatgt
    18301 attcaaacta aatcaattta ttccatttca ccaaactgga actctctgtt aaataaaatc
    18361 tagccctact tcttctcttc atagcattta tatattcaga ttatttcatc aattacaaga
    18421 aatttttctt aacttactca taatatatta ttatttttat attttgtcaa ccttttttat
    18481 tattatatac atgttttttt acattatact acttttttat attttttacc aatacccaaa
    18541 atttattttt caatcaaaag atttatttgt ttattgacta tattactctg actcaatctt
    18601 atatttattt tcttatttaa aaatgcgttt ataattatta aactaataac tgttacatca
    18661 aatataaaaa acagcaataa aattattatc aaaaataaaa ttctagcata taataatttt
    18721 ctaaacttag ctattataaa gttttgtagt gacatacatg agtctctaat gataaaatag
    18781 acacttatat aggttattga tataaagatt gtttttaaat aaacagaatc aactttaaca
    18841 ttcaacagtt ttagaacttc aaaaatggct agataagaaa cacatatgta aaaagctttt
    18901 tttgagcaac ataaaaattg gtttaaattt ctaaagttct taaatattaa aaattttttt
    18961 aaagaattag aatctaaaat atgcaattta ttccctaaaa ttaaacttaa taaatatatg
    19021 caaaacacca taccaaaagg aaacaatgct atcattaaat aataaataaa atttgtatac
    19081 ccattaaaat aaatccattt gctatatcct tgaaattctt tcataaaact ataacctatt
    19141 aatgttgaag catatatatc aatgaaaacc attacaataa ccccaaatac tgaaccatat
    19201 actaaatcat ccataaccat tgtaggctta tttattagat agccacacat tataccaagt
    19261 aatacactct gacttgccca aatagcagtt cctagatttc caagtaccag agaaattatt
    19321 aaaagcgaag taattccaga taaaatggta tactttaaat cacatttcaa gcagattata
    19381 caaaaaaata ctggcactat aaaatctaag taaatagcat atccaaatcc agtactcaca
    19441 gctataattg ttactactat gaataaagat gacaataaag ctgcttcagt taatttttta
    19501 gtagtattca aaacactgcc tccataaatc ataaattttc taactaaagt tttgttttta
    19561 atatagtata tcacttttta aaaatatttt taataaatat aaattttaat aaaggtattt
    19621 atgttaaaaa tggtataatg tatcttaata ttcagttttt taagatgcta ggaggtaatt
    19681 actatgttta aaattaaaca ctttaatgat ttgagtttag atgaatttta tgaaatagca
    19741 aaatcaagat atgaggtatt tgcttgtgaa cagaagatat tttcattaaa cgattatgat
    19801 gatatagata aaagctctta tcacatattt ttaaaagaaa atggattgat ttgtgcttac
    19861 gctagaataa ttcctaaaga atacagctct tataatgatg tttccattgg tagagtttta
    19921 gttctttcta gtcatagaag aaaaggatta gcaaaacaaa tgatggattg tgctatagat
    19981 tttataaaag ttaacttaca cgaaaataat ataaccttat cagcacaaac ttatataaag
    20041 aacctttact tatcttgtgg ttttaaagaa atctcagaag tatacgacga agcaggtatt
    20101 gaacatatta aaatgagatt atagtgttga caagctaata ttgttaatat ataatttaag
    20161 tataaattaa atattgaatt gatatttagg tatttgaaaa taccttacat agagtcagaa
    20221 ggcttttgct ttctgacttt tttattatca aaattcaata attatatgga ttcaaagtgt
    20281 taatttttat tctatattct actttcccca aaagtaagaa ttatacccaa ctttgtatga
    20341 taggcatctt gcctatcttt tttttgtaaa agtaacaagg taataatata atgcatagtt
    20401 taaaataaga agattagccc aggctaaatt tcaagcatgg aggtgctatt atgaaaaacc
    20461 ttaacgatat tcaagtgaaa aaaactgtca aagttgaaga tatattatct agtggtaatt
    20521 taagagaaag aatgttagcg cttggtctta ctagaggagc tgttatagat gtagttagaa
    20581 aaggtccaaa aaataattta actgtctata aaatcagagg tagcaagata gctctacgac
    20641 aagaagaaag tagcttaata ttagtttctg acatttaaaa atttctagca ggaggatatt
    20701 aatatggggt tgacacataa ctcaactaaa atgagttctt taaaagacat gtttgatata
    20761 gacaataagg aagaccagtt tgtaattgca ttggctggca atccaaatac aggtaaaagt
    20821 actgtattta atcatcttac aggacttaga cagcatactg gaaactggcc aggaaaaact
    20881 gtagctacag ctcgtggtaa ttttaaatat aaaaataccg aatatgcatt aatagattta
    20941 ccaggaacat attctttatt tgccttatca caagaagaaa ttgtagctcg tgattttata
    21001 tgttttggta atccagatgc agtaatagta gtatgtgatg ctacatgtct tgaaagaaat
    21061 ttaaatttag tatttcaagt gatggaactt acagataaag ttattttgtg tattaattta
    21121 atagatgaag ctagaaaaaa aggcattact attgataaaa aacttttaga ggattctctt
    21181 ggtattccag ttattttaac tgctgcaaga aatggctctg gtatggatga actattggat
    21241 actttaaatg atgtatcttt tgacaaatat aaattaaata ataaacctgt tagatacaat
    21301 gaaaatatag agaatgtggt aaaatcaatt caaccagaat tggataatat tataccaggt
    21361 ataaattcta gatggttggg acttagactt attgatggcg atgaaagtat atttgaatct
    21421 atgagtaatt atatagacaa agattctata gatgctatta atgaagtaaa gaaaaagatt
    21481 ccagacaata taaataaaca gaaaataaga gatgagttta ctaaaatcaa ctatgattat
    21541 gctaaaaaac tgagtgatga gtgttgttct aatgttgcta aaaaatcaac tgatagagaa
    21601 gaaaaagtag ataaaatatt aacatctaaa atatttgggc ttccaataat gctcttatta
    21661 ttaggtacta tattgtggat tactatagaa ggagctaact atccatccac tttattatct
    21721 aatttattac tcggatttga gccaagtatt tcgggtatat taaatagtat taattgtcca
    21781 tcatggttaa atgatatgtt ggttttagga ttatacagaa cattagcatg ggtaatctct
    21841 gtaatgctac ctcctatggc aatatttttt ccattattta ccctacttga ggattttgga
    21901 tatttgccaa gagttgcatt taacttagac cacctattta aaaaagcttg tgcacatgga
    21961 aaacagtgtt tgactatgtg tatgggattt ggatgtaatg cagctggagt tattggttgt
    22021 aggataattg actctccaag ggaaagactt atagctatac ttacaaacaa ctttgttcct
    22081 tgtaatggtc gttttcctac tttgatagct atatctacaa tattttttag ctcagttata
    22141 accaactctt tcgtatcaag cgtagcaact gcactttgca taactttact gataattcta
    22201 ggtgttataa taacattgtt ggtttcttat actctttcta aaacgctatt aaaaggagtt
    22261 ccgtctacat ttacattaga acttcctcct tatagagttc ctcaaatagg aagaacttta
    22321 tatacctcta taatagatag aacaatattt gttttaggaa gggctgtaat ggtagccata
    22381 cctgctggtg tcataacttg gatatttgca aatatatata taggagattt aagtatatta
    22441 tcacatgttg caaacttttt agacccttta gctaaattaa ttggtcttga tggttttata
    22501 ttacttgctt ttattcttgg attcccagca aatgagatag ttgtacctat acttttaatg
    22561 gcttacctag caactggttc tatgatagaa ttagatagct ttagtgcttt aggtcaagtt
    22621 cttagagaac atggatggac ttatttgaca gctttaaatg ttatgctgtt cagtttactg
    22681 cattggcctt gtgcaacaac acttttaaca ataaaaaaag aaactggtag tttaaaatgg
    22741 actgccttag gattcttaat gcctactata cttgcttttg ttgtttgttt tttaacaact
    22801 acagtttaca atttatttat ataattagta ttaactgaca gtagacatat attagagaaa
    22861 ccatttaaaa atttatatac tttattataa agcatagaga tatattcaat gataagtaaa
    22921 attacttaac atttgaatat atctctattt taattcttat ctggatactt ggattgaaat
    22981 ttcagtcata taattatctt cattactttc acaaaaaaag tcaagtatac tctcctcata
    23041 cgaatttcca acaattttat attcattttc atatatatat tttttcaatt tttcgtaaga
    23101 tttatatgaa tcctcatatt ttccaatatg ttttatgcaa gcatacattc cttctggctt
    23161 tacatatagc tttttatcct ttattttttt atctatcttc aaataaaaac ttgatatact
    23221 taaatagtcc ccatttttta tattttcatt acttactatt actcccaact catatccttg
    23281 atacaaattt ttcgatttac aataattggt aaaatctatt aattccatca taaaatcact
    23341 attactcata ttactcaaat cgcttgatag aactaaatat tcttcaaact ttttggatat
    23401 ataaatttct tcactattca ttttagaaat tccttcaact gttatattta ttctattttg
    23461 catcttagaa cttatctttc ttagtttttt tattttttct cttatctttt tttcttcttc
    23521 tttaagcatt ttcacacaaa gctggggagt tctattttgt atatactctt ttatttcctc
    23581 taaactcatt cctatttctc ttaatgattg taatatatca agtgtatcat attgataaac
    23641 tgagtaatat ctataattat ttttatcttt atattcagga gaaaaaatac ctattttgtc
    23701 atagaaaatt aatgtctgct tagatatacc acacaattta gcaaattcac ctgttgtaaa
    23761 atactgtttt tccaagggtt atacactcct tttctttttg ttgtctatat agttactata
    23821 ttctttatta tttactaaat caagtagtta ttattttaga aaatcaatat ggttttgatt
    23881 ttaaagctta aatatcagtt agatgtcagt tataaatatt ttacccattc ccatcataaa
    23941 aaagatatcc cctcttaact tttggatgga atattatatt tatacttgtt agagtgaaaa
    24001 ttgtaatagg tgctacaata agatatttaa ttaaacataa agttaattat tgtaataaaa
    24061 aatctttaga taaattagag ttaaagtatg gaaatataga tagagaaaaa gctgttaaac
    24121 tagaaatatt ttatcaatat ttaatagaac ttgaatatat agaaatgagt ttattaataa
    24181 gaagattaga tactgcaata acatcattag cattagtatc tattataaca atagcatcat
    24241 attatttaat cagaaaaaat gtgtaattat gtaagctatt tataataaaa cactgataaa
    24301 attaataata aaaagataat aggatttcta tactaccttt ttgtttttat aatatagtgt
    24361 aattttatta tatttttgta tgctaatata actagataat cataagataa cacattaaaa
    24421 gaaaattata ttctgtatag ttagtataaa acgtaagtaa tataaattta tgtaaagcaa
    24481 caaaagatgg atttacattc catatagtta atataaaacg atttcaaatg attagaataa
    24541 aaatatcaga attgctattt atattccata tagttaatat aaaactataa agtgttactt
    24601 ttatttattt tattttttac ataatttaca ttccatatag ttaatataaa acgcattata
    24661 tggctgtgtc attttgcatt ctattacata tttacattcc atatagttaa tataaaacct
    24721 gcttaatgca gaattaagag aggaagtgtt ataagattta cattccatat agttaatata
    24781 aaactggttg ttcctgctcc ggtgttggtg gaactggtac atttacattc catatagtta
    24841 atataaaacg aatatgtatg gataattttt tacttaacat attagcattt acattccata
    24901 tagttaatat aaaacctgct gtaatttctg atgaagcttc tccactacca ccatttacat
    24961 tccatatagt taatataaaa ccccaaaata aacttagtat tttcaacact tacacgtata
    25021 caactctctt aaatttgcag tgaacgagca atagtgcaat tgataacgct tatcatacac
    25081 tctcaacgcc ttatatttca actgttacgc caaatttttt cacaaatatc gctcactgca
    25141 aaattcctat aattttatta tatcataaat atattacttt tgaatattga taccaattta
    25201 taccataata aaagcaaaaa aacgtaatct atctacatta gatttaaatt ctataactta
    25261 aagtttttta cataatattt atgcttgttt aatcaatcta atatatcatt cttgtatatt
    25321 gcttttaata gtcttttttc ttaaataaat atctatctga acaagcatag tttaattaaa
    25381 aacttttgta ttcccttaaa actgtatcta cctcttatta ttttatttat gatatattat
    25441 ttttaatcta aaaatagata tctattttta ttatggttat ccctttttaa aatactttaa
    25501 tcatatacta ttcccaattt aacatccatt gaaatgctat tttcttatat tgcaatttat
    25561 aattgatata tcttcaatat aataatttaa tgtatttttg attttaaagc ttttcagtga
    25621 tattattgat aaattagaat taattatcta gctttaaaag gtcaaagatt tctgttgctg
    25681 tctgcggttt tccaaataaa tatccttgta tgtaatctgg ctttatttgt ttaactaaat
    25741 catactcttc ttgtgtttct acaccttcta aacatacttt tattcctaca tcatgacaaa
    25801 ttgcaacaat aaaatgtata aatgtagcat caaacttact ctttaatata tctttaacaa
    25861 atactctatc aattttcact atatctattg gagaaaattt taaaacttct agagacgagt
    25921 atccagtacc aaaatcatcc atagcaatat aaattcctaa atcttgtaaa gccttaaatt
    25981 taaactgtaa aatactcata ttttgtactg tatgactttc tgtcaattct aaaacaagat
    26041 tttgataagg aaaattttca tcatctataa tttttactat atcttcaata aatgtgtctt
    26101 ctaatatttg aacagctgaa acgtttacac tcactttaaa aaaaggatag taatcaatcc
    26161 atttcctaaa agtacgtaat gccattcgaa gcacccaagc ccctacaata tttatcatat
    26221 cattttcttc taatattgga ataaattcca aaggagaaat tgctttgcat ttgtcattag
    26281 tccaccttaa aagaacttct acacctatta ttttatgact ttctgtatct acttgtggct
    26341 ggaatcgaag actaaacccc ctaaaatcat cattaattga tgcctttaaa tcccgcatca
    26401 tttctaatga atacatttta ttttttaata tttcttggga gaaaaaaaca agcctgtttt
    26461 taccatgctc tttcgcatat tgtaaagagt aactagcaca cttataaagt tcttttactg
    26521 tatctccatg ttttggatat attacacaac cagcagaaat tgttatattt aatccatatt
    26581 ttctccatag ttgaaggtgt ataatcatat tctgtatttg attatataga gttagaattt
    26641 cattttcttc aacattatca acaagaatgc ccatttcgtc cccatcaagt ttataaagtt
    26701 cagcattatc tggtaaaata gattgtatag actgtgctag tgtttttatt atattatctc
    26761 caaaatccct atcatacatc tcattaacat ttttaaaatc gtcaatatct aataatacta
    26821 tgcataattt ttcaatcata ggatttgaaa ttttatcttc aaatacactc ataaattcat
    26881 gataattcag taactgtgtc aatgaatcaa tcttattttg tttacctaat tgcgtcatta
    26941 ttcctgcaaa aatacttggt tctccaaatt catcacgcat tagttgacct ctacatctta
    27001 accatatata ttctccacta cgatttttag ccctaaattc cactgtatga taatccatct
    27061 ggtttttacc tatttcagtg tttgacttat aaaaacgatt ccagtcttct ggatgtacaa
    27121 tttttttcca gtaaacaagc ggattttcaa caatttctcc tggtaagtca aataattcaa
    27181 cttgtgatgg tgaatatcga aatacgcctg ttttcatatt gcaaatgtat atatattcat
    27241 ctgtacctct aatcaaagca tcataaagca atgtagaatt ataatcaaaa ttgtctcttg
    27301 aaaaattaaa aactcctttt tcttctttat tatttgatat ttcatgaaat tcattaatct
    27361 taattggttt atttaagctt gttgagtttg caatatctat tgattgatgc atatgaacaa
    27421 ctgtgccatc ttgccatgta attaaactat cataattttc aaaaacacga tttaacttat
    27481 tacatttttc ataccacttt attaatactc cttttttatc attctttaat aattctaaaa
    27541 ctttacaaaa actacaagta gaattttttt caggatataa tacttgccaa caaacttttc
    27601 cttctggatc taaaatatta tattcttctt tcattttttt gttcataaaa ataatttcat
    27661 tagtatgaat atttgtaaca tatatattaa tctgtagttg atttaatata acttcaaaat
    27721 tatgtttgtt catatactta tctcctccat agttactgct ctttataaca acattgttaa
    27781 aattattctt tttagaagat ttacttataa cttatacata tacactaaat accttaattt
    27841 aattagaaag tttattactt catattttaa attataattg ataaaaaaaa atacagcaat
    27901 atagtattac caatttaaaa aaaattaata ttacataata catctctctc ttatattaaa
    27961 ttttaacttg gtactaatct tgacaaattg tccacaaaaa taaattatat attttattat
    28021 tgttttaaat ttttataaaa aatcagtatt attgatacta ttgaagttaa aaagcattaa
    28081 tttctaaaaa catcataatt tttctaatag acttaatcac ttttaatata tatagtaaaa
    28141 caaaaaactt atattttata aatatcataa tttttttact gatattttat tatataaatt
    28201 ttatagaatt aattgtcaat tttttatgaa aatggtaaga tatttatgga tggtatcttg
    28261 ttataagaac tatactttaa atgtttttaa ttattttgtc ttatgtaact catatcctca
    28321 ggaatgagat tagaaattaa gatgttgtat cacaaagtgg aggtgatact attaaaatag
    28381 gctttattgg ttctggaaaa gttggaacat ctttggcaaa ttatttttta tcaaaaggtt
    28441 attgtgtttc aggcttttat ggaaggaatc aattatcttt attagaatca acaaatttaa
    28501 caaaaacaaa gatttacagc aatttgaaag atataattta tgaaaacgat atattattta
    28561 ttacaacatc agatgattct attgaaatta tagacaaaaa actttccaaa tttaatttaa
    28621 aacataaata catttgccac acaagtggct ctttaaaatc tagtatattg ttctgttcaa
    28681 aaaaagcagg tgcattaatt tattctatcc atcctatatt tgcattttcc aataaaaata
    28741 ccaacataaa aaaaatgaaa gacatttgtt tttccataga aggtgataat gaacaagatg
    28801 atttagttat tcaaaatttc atagatgatt tgggaaacca attttttata agagataagg
    28861 atacttcatc cacttatcat ttagctaatg ttttagtttc aaatttagta ttatctttac
    28921 tagatatagg agtaagttac tttattaaat taggtttatc tgaagaggaa tctttaaaag
    28981 ctatcagtcc tttagtaaaa aaaaatatag aaaatatact tgataatggc tttactaaag
    29041 ctcttactgg tcctgtttct cgtggagata taacaccaat aagaaaacat ctatctgtat
    29101 tggataaaaa agatgaggat atttacaaaa tactatcctt aaacctacta aaaataattg
    29161 ccttaggaaa tgacaattca ttaaaaggta taaaaaatat tactatagaa aatgcaatcg
    29221 aaaatttaat aagtaaatct gaaaaataca aagaaattta caaactttta ggaggaaaaa
    29281 acgatgaaaa ataccataca gacttttaag aatgctaaat atgaaggaaa aaaactatct
    29341 atgcttactg cttatgacta ctcaattgca aaaataatgg atgagtgtga tataaatggt
    29401 attttaatag gagattcatt aggaatggtt ataaaaggtg aagaaaacac tctatctgtt
    29461 accatagatg aaattatata tcatacaaaa gctgtaaaaa atggtgtaaa aaatgcctta
    29521 atcgtaagtg atatgccttt tctatcttac catgtttcta tagaagatgc agttaaaaac
    29581 gcgggtagac ttataaaaga aggaggagct catgctgtaa agttagaagg tggctcaaac
    29641 gttataaagc aaatagaaag cattgtaaat gctcaaatac ctgtaatggg gcatttagga
    29701 ttaactcctc aatcagtaaa ttcatttggt gggtttaagg ttcaaggaaa taccagtgaa
    29761 acagcaagac aacttattga agatgctaaa ttaatagaaa aagcaggtgc attctctatt
    29821 gtccttgaag gagtgcctac gaaaatagct gagatggtaa ctaattctat ttcaattcct
    29881 acaataggta taggggcagg aattaactgt gatggacaaa ttttagttta tcaagatatg
    29941 ttgggaatgt ttggagattt tgttcctaag tttgtaaagc agtatgcaaa tataggagat
    30001 ataatgaaag attcaattaa aaattacatc ctagaagtta atacaggtac atttccacaa
    30061 gaaaaacaca gcttttcaat aaatgaatct gagttagaaa aattatacta atattaagga
    30121 tggtacaaaa tgcttgtaaa agaaattaaa ttactaagaa atataatcaa agattggaga
    30181 aaacatggct attctatagg gcttgttaca acaatgggat ttttacatga aggacaccaa
    30241 agtcttataa aaaaagctgt aaaagaaaat gataaagtag tagtgagtgt atttgtaaat
    30301 ccaactcaat ttggaccaaa tgaagatttt aatagctatc caagagatat agataaagat
    30361 tttaaatatt gtatggatag tggagcaaca gtagtcttta acccatcacc agaagaaatg
    30421 tatttaaaag gtaattgtac taccattaat gtttctggac ttacagattt tctttgtgga
    30481 gctaaaagac ctgttcattt tggaggtgtc tgcctagttg tttcaaagtt tctaaatata
    30541 gtaacacctg ataaagctta ttttggagag aaggatgccc aacaattagc tgtaattaaa
    30601 agaatggtca aggatttaaa catagataca gaaataatag gctgtcctat aattcgtgaa
    30661 aatgatggat tagcaaaaag ttcgagaaat acatatctct ctgaggaaga acgaaaatct
    30721 gctctaatat taaataagag cttaagttta gcaaaagaag aattagtaaa aggcaatcta
    30781 aatccagaga atataaaaga attaataaca gctaaaataa attctgaaca cttagcaaaa
    30841 atagactatg ttgaaattgt agatagtgag acattacaac ctgttaagca aatagaacat
    30901 tctatacttg tggcaattgc tgtgtttata ggaaaaacca gactaattga taattttaca
    30961 tttgagttaa atatatagtc tataatttta tataatatat ctaaaaaata atagaatacc
    31021 taaaaagtaa taaattacct aaaaaataat aaattgctta gaaaataata gattacaata
    31081 actaaaattt taaaattaaa ttccttaaaa gtatgattaa ttataattat ataagtatat
    31141 tcttattaca cttatattaa tttatattaa atatctacta actcaaatat tcataattaa
    31201 actttaaact ggataaattt tcttttaaga atgaaagttt atccagtttt gcgattataa
    31261 taaccagttt tacatatcca cttgtaaaat atatctaagc aatatatcat actatataga
    31321 tttatgagtg aaataatatc tgctatttac tgaatatttt tatttttcgt tttttagggg
    31381 gattagttgt gtttaaagat aagattgatg aatgtgttca tataatgact gcatatattg
    31441 ctagtttaaa agaatactat tcattcatag aaactcaaat tggtgatttt attaaaaaat
    31501 atggagaaga tgttgtagag ttatgtctcc atagagtgat gattctacta tgcgaatgtg
    31561 gtttggcata aaattaaatt tattaaaatg ggtaagaaga atcctatata atattcttct
    31621 tacccatttt aatatatcaa tttcatagct tatcgtttaa aatattttac atccattact
    31681 agacaacttt acattctctt tttaattcta gtatatttaa atcattttag ttgctcctta
    31741 tttattctta ttacttgttt tattttataa ataaaataat tctttttaat aatgtttttt
    31801 gttgatattc ctatcacaca tccaattatt tatcattgtc ttgaaattgt ttgcatactt
    31861 aatttaatcc aattgaaaca ccccagcata gaatcccctg taaaatagaa gttggattaa
    31921 atcctaacat ctatacagaa aatactactc caagcacaag caatataatg gaatatattt
    31981 atcacttaat tttttatact ttttaaatcc catacctaaa gcattaagtg cagctattag
    32041 aattaataat tgttgtggta taaaattatg cttgcttcat atttattcat tttttactat
    32101 aaaagttctt gttttacaaa aaacatttgt tttgtatcaa aataatactt gtaaattaca
    32161 taattctcat aaaaatttct agtattactt gtactcttaa taaataatag ccaacaagta
    32221 ccttaaatca ttatatctat atctaataag aaacacagta agataatttt ttcgcccata
    32281 acttaataaa aactgttgat attagtagca attgaattta gttaatttat ttataatata
    32341 cataaattta aatattacga ataaagtatt ataaatagga tactttctaa agggaggaaa
    32401 ttatgataga taatcaaaaa tatgttattt tatcactaga attacattta tttttttcaa
    32461 gaattatgaa agagcatgct ctttttttag aagcaggatt cacaaataaa aattataatc
    32521 ttgctatgga agctgaccac tataaaaagc aatttgaaga tttattatca tacactgtta
    32581 gtgctagtaa tggtataatt agacctgata tattatattc agaagagctt gtaactactc
    32641 tcacatcagt tgcagaacaa aaaacagaag agtttacagg gatagaaata aacaaaaaca
    32701 tcactacaag agaattaaat ctacaaagtg gtgtaaaccc acaagttggt caagacttag
    32761 tgaactatgt agctcaactt aactctgatg caataagatt acttgatggg cttattaatt
    32821 ttaaagaaag agtcttagat ggtgtactat catgtactat atttacatca aactaccctc
    32881 tacttcttga acatataata catgaagcaa atttatatcg ttattatgta gttgaccttg
    32941 aaaataaaat agatattgag tcaaaaaacg ctaaagaaat agaattattc tgggaccata
    33001 ttatgatgga acatgctctg tttatgagag gattactaga cccctcagaa ggtgaactaa
    33061 taaatacttc aaatgatttt gctataaaat ttaatgaatt aattgaaaaa acaaacgaaa
    33121 tgactgattc taatatcaag aacattacag aagaaactct aaatgaaact gttgagttta
    33181 aagattttaa agaagcagga gcatcaggaa tagaacagtg taagataaaa tctataatat
    33241 taccactttt agcagaccat gttttaagag aggcaaatca ttatattaga atattggaga
    33301 gttataaaaa catgtaatta aaaattactt ttaaaataat ctttgcatat ttagataaaa
    33361 taaaggtaca gttaactgta cctttatttt ttataaactt ataaaattta aacaagttat
    33421 tcataaaata aaataataat catctataac ccacaacttt attttatatt aaataaaaag
    33481 tattagtgat tatgttttat aggtatttct ttattcagtt atttattaaa aactaatagt
    33541 aaatcttata ctaatcgcat atttatgtta taactatatt gtaactattt tcgtaatctt
    33601 aggaaaagat tacttataaa attaacctta tacaataata tatcgtataa tcttaattag
    33661 cataatagtt acaatattaa aatttaaata tgggagtgat tttagtatga taagacaaac
    33721 accattagag aaacgatatg acaagctagg tcctcatatt gtaacagcac tcaaaaaacg
    33781 ttattttgat gcttattact gtaaaactag aaatgaagct ttgcaacaaa ttttagattt
    33841 aattcctcaa aatcatgtag tatcatgggg aggatctgaa acacttaaag aaatgggcgt
    33901 acaaactgct gttagagaga aaggatttaa agttattgat agagatttag caaaaactcc
    33961 agaagaaaga actgaaatta tgcgtcaagc acttctatgc gatacttttt tgatgagtag
    34021 caatgcaatt agtgaagatg gacaactctt taatattgat ggaaatggca atcgtgtagc
    34081 tgcaatgata tttggtccaa aaaatgttat agttgtagct ggtatgaata aaattgtaaa
    34141 aaacattgat gatgcaatac aaagaactag aacaattgca tctccagcag ttgttcagcg
    34201 ttttcaagat gtcaatacac catgctatat taatggaagt tgtatagatt gcacaagccc
    34261 tgaaagcatt tgtgcataca tggttactac aagaatcagt cgtccagcaa aaaaaataaa
    34321 ggtaatattg gtaggagaaa atcttggtct ataaaatata catacatgta aatagctcta
    34381 taaataataa aatcatatga aataacttat ttctaaaagt ggtagaataa aagcttctac
    34441 aagactttca ttctaccact tttatattct tttaatttgt gtttctatat tattaattgc
    34501 tccgattttc atatatatta ctaactattt ttattttcat aatttttttg ttcttcatca
    34561 agctgtttat aataatcttt attatagtca gctagataat ctataccacc tcctgtaatc
    34621 acatttaata atttcattgc agattcttga ttaactttac aaacataatt atcaccagat
    34681 ttaacaagct ctaatgtaat attaaattct tttttctttg cagaatcaat atctttcata
    34741 gttggatttg gcatcatttc tcctagttta ggaggattct tttttaaaat agaaaccata
    34801 tcagtattgt taatttttaa atctacagtc actttatcct tattattctt tatatctgaa
    34861 atttcccaag tcatattttt agaatacatt ttaaatcctt ctttatcttc gtatataaga
    34921 ttacctaacc ctgattttgg gaaatactta tcaacagtat ctgcatcttg tgtttttatt
    34981 gaattaaaca tactatccac ttcatttttt atcttattat cattagtaca accagctaac
    35041 accagtactg atattgcaaa cattataata catataataa atttcttcat taaattatat
    35101 ccccctatac ttttttgcac aaatattatt ctctttttta tcttttgaaa aagttgtagt
    35161 aattgcattt tgtggacaaa cttttataca ttcaccacac ctaatacagt ctggactatt
    35221 tacatcttta tatattggta tatcaagctt acattttgtt tgacatgctg tacaatttgt
    35281 acatttatct ttatcaattt taaatctata tattgaaata ggattaaaaa aaccatagat
    35341 tgctcctaaa gggcatatat acttgcaaaa tggcctataa gtaatgattg acatcaataa
    35401 tatcaatagc aaaatactta acttccagct aaataaaaat cctattgatt ctcttaaatt
    35461 ctcatttcct aaaataagta gtattcctcc caaaagtgtt cctgaagggc aaatccattt
    35521 acaaaaccaa ggatttccac cccctgctac atttacaata gcaactggca aaataattac
    35581 aaacattatt aagactatat actttagata ttttagatat ttatcaccat aaactttttt
    35641 tatctttact ggaaagggta ctttatgtag taaatcttgt acaagtccaa agggacaaag
    35701 ccaaccacaa acaaatctgc caaaaaaagc accaaatgcc attaaaaaac caacaacata
    35761 aaatgagaat ttatactctc tgcttgataa aactgcttgt aatgaaccta ttggacatgc
    35821 tccaagtgca cctggacatg aataacaatt caatccaggt acacataatt ttttactttc
    35881 tcctccatat atagttcctt ctaaaaatcc atttacatat ccatttgtta atgctgtaaa
    35941 tgcaacttga gtaataagtc ttatattatt atttacctta gataataact tcatccctct
    36001 tctcctaacc aataccaata cactcaagac aaatcataat tgctttagtt aatactgtat
    36061 ttgtttctcc acgatatgta cctaatgcaa taaatataat actaattgca ataatagaaa
    36121 tgcctttttt attatcttta ataaagttac tcattggctt ttaccatttt tagtctttca
    36181 tctataattt ttttccaatc ttccttacta tttgcaccta caaccttctc acccacaaag
    36241 tttcctttct tgtctacaaa ataagttgtt ggaaactcca taactctttt aaaatcagtt
    36301 tttttaagtt cttcagatac agtcaattgt tggtaagttg catctgactt tttcataatg
    36361 tctttaacta aatttttctc ttcatttgaa agaccagttc tcatatcagt tttatcaact
    36421 tctacaacta atccctttat agctacattg gaattattac tctcatattc ttttgataat
    36481 gcttcaagct ctggcatttc acccacacat ggtccacacc aagtagtcca gacattaata
    36541 agagtaagtt ctttatttga aaatatctct tttgttacct tatttccatc aacatcctcc
    36601 gtatctaaat tactaaacca ttcactatta ttcttgtttt tttctactgg cttagattct
    36661 tttttgctac atccagaaat catacctaaa acacaaatac atcctaaaac tactatgaaa
    36721 aaccttttca tatctcacac tcctagaatt tatatagtat ataaaatcgc tgcttgaaat
    36781 aaaaataact tatcttctat attaaagtaa ttatatttaa taaataagag ctaatttaaa
    36841 aaaagatata cagttaaaat ctatttcttt tcagacaaaa tcttatatat atataatagc
    36901 ttgtaaatct taagattata tacatatatt tctaaagatt ttcttaagaa acagttagat
    36961 tttactaata taagtttatt aattagcatt atactaattt atcttaatat gattttttgt
    37021 tgattttaag ctgtttatcg tataaataaa atttttcttg actatatagt tactatatag
    37081 cttattatat atagagagta ataaaaggag gtaaaattta tggaaaattt atttacaaga
    37141 aaattcacta cttttgaatt tctaaaattt gtttctcctg caattatatc catgatattt
    37201 atatctttgt atacaataat agatggcatc tttgtatcga cattagttgg ttctgatgct
    37261 cttgctagta taaatattgt actacctata attaaccttg tttgtggatt tggaataatg
    37321 atggcaactg gtggaggtgc tatcgtttct atacgtatgg gtgaaaatag acaggatgaa
    37381 gccaactcta cattttcttt tatagttttg ttttcattga ttgttgggat tttattcaca
    37441 gtaatctcat atttctttat caaagaaata tctattttgc ttggtgcaac agataagtta
    37501 ttaccatatt gtataactta tggtaaagtt atgattttat gtacaccatt ttatatttta
    37561 aaatttatat ttgagtactt tgcaagaact gatggaaatt ctaaatttag tttatttcta
    37621 tcagtcattg gtggtgtaac aaatataata ttggattatg tatttattaa atattttgga
    37681 atgggtcttt taggagctgc agttgcaact gctataggta ttattttaac ttgtgtttta
    37741 ggtattattt acttcttatc taataaatct acactaaaat taagaaaacc aaaaaccgat
    37801 tttagactta taagagatac tatgataaac ggttcttctg aaatggttac agaattatct
    37861 acaggaatta caacattctt atttaatgta gtagctttaa aattagcagg agaaaatgga
    37921 cttgctgctc ttactatagt attgtatgct cattttttaa tgacatcagt ctatctagga
    37981 ttcgctgctg gagtgtctcc attaataagc tataattttg gtgctgaaaa cagtgataaa
    38041 ttaaaagaaa catttaaaca ttctctaaaa tttatattta tttcttctct tttagtgttt
    38101 attattgctt tagtatttgc accatttatt gttagggtct ttgtaaatcc agataacaca
    38161 gtatttaaac tagccttaca aggattaaaa atatttgcat ttgctttttt gtttgttggt
    38221 ataaatatat ttgcatcagg attttttaca gcatttcaca atggaaaaat ttcagctatt
    38281 atatctttta gtcgtgcctt tgtttttata atcataggaa tcataattct tcctcctatg
    38341 ttaaacatga ctggattatg gcttacagtt ccatttgctg aggttataac catatttata
    38401 tctattctat ttataaaaaa atataaatgt agatataagt attaaaaatt aatacttaaa
    38461 atcaacattt attaaaacta ataaacctgc tttaaaatac aaatttacaa atttgatttt
    38521 taagcaggtt ttattttagt tataataagt catttgcata ctctttaatt ggtgcttttc
    38581 taagtaataa aattataaat attatgcaaa taactataat tcctaccttt gttccaaata
    38641 aaataaaagg attctgaaat gaataaataa ttttttctaa atacaatagc attttatgca
    38701 tatttttagt tgcaaaatta actatataaa ttaccattaa tatcggtaat cctatcaata
    38761 tagtaatact agtaactttt ctaactctat atgtaaaagc tccaagtaac actcctataa
    38821 aacctataca tatttcattt atacatattt gtacaaaata atttaaataa gttagtggca
    38881 tacttgatgt tgaaggatct atcagtgctg atatagatgt ccaaatcata tctctcttta
    38941 gtaaaactga tagttctata ctgtaacctg ttataatttc tataaataac ttcgataaaa
    39001 aaatcaaaac tatacctaaa atagaaatca caaagcttaa aataattaaa tctatgacaa
    39061 tagcttttat acaacttttt ctatctgctc ttatacttaa agctcctgaa aagtctttat
    39121 ttgctatatt tactccatac acaaatagca gtatagttat atatgttaaa ataggattca
    39181 caatcgtgga taaattagtt ttagatgctt ctccaaaaat cttgagaata aacactggca
    39241 aaatattcat aacaattccc acaatcataa atataattat atacaattta gtatttttat
    39301 taaaaaattt tatatatggc tttaattcat tcaattacaa ttcctccttc ttagtcatgt
    39361 taacaaacat atcttgtagc cctatgtatc ctacatcaat atttgaattt ttaagtattt
    39421 tttcatcatt ttcactaaaa tcaccatagt aaaaataagc aactgcattt ccaaatgcct
    39481 ttttaggttt tatatttttt atacattcta atttttctaa ctcttcttta tttccagtaa
    39541 tataatgagc tttttgtttt atgacatcaa tttcttcatc tataataatt tttccctcat
    39601 ttaatattat tacatgctcc agtaaatcat ctatttcatc aatcaaatga gttgatatta
    39661 ttattgtcct tggatttttt atataactat ctaaaattat gttataaaac tcttgtctat
    39721 ttactgcatc caaaccaatt gttggctcat caaatatggt gatagctgaa ttagaacaaa
    39781 tacctattat atttgaaagt atagttttca tacctcttga cagttgttta tacttttttt
    39841 tagtatttaa atcaaaatat ttgcataatt ctttttctaa gcctttatca taacttttat
    39901 aaaaactaga agaaaattca aatatctgac ctactttaaa atctggacta taaaattctt
    39961 tttccctgac aatacaaact tcttccaaaa cttttatatc ttcttttggg ttctttccta
    40021 atatttctat ctcaccttca ttttgaatta actgatttac cattatattt aataatgttg
    40081 tttttccagc
//
LOCUS       DAGQVA010000031        38919 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.031, whole genome shotgun sequence.
ACCESSION   DAGQVA010000031 DAGQVA010000000
VERSION     DAGQVA010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.031"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            94..996
                     /locus_tag="MIV85_001795"
     CDS             94..996
                     /locus_tag="MIV85_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2961136.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKESNWKIIG"
     gene            complement(1195..1530)
                     /locus_tag="MIV85_001796"
     CDS             complement(1195..1530)
                     /locus_tag="MIV85_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961137.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKPSVKTIQLVCMEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            1480..1689
                     /locus_tag="MIV85_001797"
     CDS             1480..1689
                     /locus_tag="MIV85_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961138.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSRPNETDLIELKNAISK"
     gene            1782..4445
                     /gene="mgtA"
                     /locus_tag="MIV85_001798"
     CDS             1782..4445
                     /gene="mgtA"
                     /locus_tag="MIV85_001798"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBY2961139.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            4461..4964
                     /locus_tag="MIV85_001799"
     CDS             4461..4964
                     /locus_tag="MIV85_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBY2961140.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            5102..5779
                     /locus_tag="MIV85_001800"
     CDS             5102..5779
                     /locus_tag="MIV85_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBY2961141.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            6026..6337
                     /locus_tag="MIV85_001801"
     CDS             6026..6337
                     /locus_tag="MIV85_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBY2961142.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            6503..9268
                     /gene="mgtA"
                     /locus_tag="MIV85_001802"
     CDS             6503..9268
                     /gene="mgtA"
                     /locus_tag="MIV85_001802"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBY2961143.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            9281..9448
                     /locus_tag="MIV85_001803"
     CDS             9281..9448
                     /locus_tag="MIV85_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961144.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            10499..10798
                     /locus_tag="MIV85_001804"
     CDS             10499..10798
                     /locus_tag="MIV85_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2961145.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFMVSVSAKRGRSLFALATFAGKGVRL"
     gene            10795..11211
                     /locus_tag="MIV85_001805"
     CDS             10795..11211
                     /locus_tag="MIV85_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2961146.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGAMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            11216..11455
                     /locus_tag="MIV85_001806"
     CDS             11216..11455
                     /locus_tag="MIV85_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2961147.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            11774..11917
                     /locus_tag="MIV85_001807"
     CDS             11774..11917
                     /locus_tag="MIV85_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2961148.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            11980..13740
                     /locus_tag="MIV85_001808"
     CDS             11980..13740
                     /locus_tag="MIV85_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBY2961149.1"
                     /translation="MQEVEVIKAKNVLARQARGKAIERLRVATYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSKYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKTQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(14229..14867)
                     /locus_tag="MIV85_001809"
     CDS             complement(14229..14867)
                     /locus_tag="MIV85_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961150.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(15277..15453)
                     /locus_tag="MIV85_001810"
     CDS             complement(15277..15453)
                     /locus_tag="MIV85_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961151.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(15507..15603)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16400..16801
                     /locus_tag="MIV85_001811"
     CDS             16400..16801
                     /locus_tag="MIV85_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBY2961152.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            16798..17865
                     /gene="rsgA"
                     /locus_tag="MIV85_001812"
     CDS             16798..17865
                     /gene="rsgA"
                     /locus_tag="MIV85_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBY2961153.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            18401..19099
                     /locus_tag="MIV85_001813"
     CDS             18401..19099
                     /locus_tag="MIV85_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961154.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            19277..20167
                     /locus_tag="MIV85_001814"
     CDS             19277..20167
                     /locus_tag="MIV85_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961155.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(20560..21516)
                     /locus_tag="MIV85_001815"
     CDS             complement(20560..21516)
                     /locus_tag="MIV85_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBY2961156.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            22219..23214
                     /locus_tag="MIV85_001816"
     CDS             22219..23214
                     /locus_tag="MIV85_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2961157.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNYFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            23192..24055
                     /locus_tag="MIV85_001817"
     CDS             23192..24055
                     /locus_tag="MIV85_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBY2961158.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            24052..24846
                     /locus_tag="MIV85_001818"
     CDS             24052..24846
                     /locus_tag="MIV85_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBY2961159.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQERELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGIFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            25131..26510
                     /locus_tag="MIV85_001819"
     CDS             25131..26510
                     /locus_tag="MIV85_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2961160.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            26958..27671
                     /locus_tag="MIV85_001820"
     CDS             26958..27671
                     /locus_tag="MIV85_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961161.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(27943..29481)
                     /locus_tag="MIV85_001821"
     CDS             complement(27943..29481)
                     /locus_tag="MIV85_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBY2961162.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            30363..30818
                     /locus_tag="MIV85_001822"
     CDS             30363..30818
                     /locus_tag="MIV85_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBY2961163.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            30867..31451
                     /locus_tag="MIV85_001823"
     CDS             30867..31451
                     /locus_tag="MIV85_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBY2961164.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(31456..31779)
                     /locus_tag="MIV85_001824"
     CDS             complement(31456..31779)
                     /locus_tag="MIV85_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961165.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            31931..32449
                     /locus_tag="MIV85_001825"
     CDS             31931..32449
                     /locus_tag="MIV85_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2961166.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(32625..33293)
                     /locus_tag="MIV85_001826"
     CDS             complement(32625..33293)
                     /locus_tag="MIV85_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBY2961167.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            33408..34823
                     /locus_tag="MIV85_001827"
     CDS             33408..34823
                     /locus_tag="MIV85_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBY2961168.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            35046..35504
                     /locus_tag="MIV85_001828"
     CDS             35046..35504
                     /locus_tag="MIV85_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961169.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            35501..36085
                     /gene="clpP"
                     /locus_tag="MIV85_001829"
     CDS             35501..36085
                     /gene="clpP"
                     /locus_tag="MIV85_001829"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBY2961170.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            36397..37473
                     /locus_tag="MIV85_001830"
     CDS             36397..37473
                     /locus_tag="MIV85_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBY2961171.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            37540..>38919
                     /gene="bclA3"
                     /locus_tag="MIV85_001831"
     CDS             37540..>38919
                     /gene="bclA3"
                     /locus_tag="MIV85_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBY2961172.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGATGATGADGATGVTGPTGA
                     TGATGANGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATG
                     PTGATGNTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGV
                     AGATGATGPT"
BASE COUNT        13510 a         5322 c         7153 g        12934 t
ORIGIN      
        1 acccgatagg atatacagac ctaagtagta gttactggca acagcactta atcggtgcag
       61 gacgagtaaa acaatagaaa ggacttgaaa aatatgttta agaagaataa gaaacagaca
      121 gaaaatgtca aagaaaaaaa ggtacgtact gtcaaggtag gcacacataa gaaaaccgtg
      181 attgcattgt gggtggtgct tattgcaagc gtgagctttg gagtatataa gaattttacc
      241 gctattgacc agcacacgac ccatgaaaaa gaagtgattg agcttcgctt gcaggacacc
      301 aacgggatag aaaatttcgt gaagaatttt gcaaagtcct attacacatg gagtaacagc
      361 aaagaagcga ttgacgcaag gacgcaggca atcagcggtt atctgacaaa ggaattgcag
      421 gacttgaata tggataccat tagaacggat ataccgacca gctctgccat tacagatgtg
      481 attgtatgga gcattgaaca gtctggaacg gacacttttt ccgctaccta cgaagtagat
      541 cagcagataa aagaggggga acagacaaca gcggttaagg caacctatac cgtaaaagtt
      601 catgtggacg ctggcgggaa tatggtaatt attcagaacc ctacccttgc accagcaatc
      661 gagaaatcag actatgaacc aaagacacca gaagcagacg caagtgtaga cgcggatacc
      721 ataaatgacg ctactgcatt tctggaaact ttctttaagc tatacccaac agccacagaa
      781 aaggagcttg cttactatgt gtctggaaat gtgcttgagt ctatcggcag ggactacctc
      841 tattctgaat tggtaaaccc tatctttacg gttgatgggg acaatgtgaa agtcaaggtt
      901 gccgtgaaat tcattgataa tcagacaaag gcaacacagg tatcgcagtt tgaattagtg
      961 ctacataagg agagcaattg gaagattata ggataattat tgaaagcgtg catttcttta
     1021 ggaatttgca cgcttttgtt aagagcatta ttctttatat ttatgaaaga catcttaaac
     1081 aaagtattaa tggcttcgca aaactttttt cttaatatat ttggattaga aaaagcgcat
     1141 cttaattgta gacttactat acatatgaat tatgccagtc aacgtattta aaatttatgt
     1201 tgttttattt tgttgtaaat cgcaagaata gataagagta atcaatggtg aaggggaatt
     1261 attaaaaata ctattggttt cttctgtccc gttccaattt gcgcattgta ttttttcata
     1321 aattacagag tggtcaatta tgtagttcag atattccata caaactaatt gtattgtttt
     1381 tacactcggt ttccatactg ccacttttgt cattctatca ctcataatac aaatattatt
     1441 atgagcaact tttctaagta gttcatttaa atttgataca tggtcaaggt gaaaaccaag
     1501 aagaagtttg tcagcactca tatgtgtcaa ggggaaatgc ctatttatgt gcgagagcgc
     1561 tatgagaaaa tgcttgccgt atccatccgt gctccaaatt tagaaggaat ggttgaaaac
     1621 tttgataagg atttatctcg ccctaacgag acggatttga tcgagctgaa aaatgccata
     1681 tcaaagtaaa ttgcaagaaa aaagcaagaa tataaatata gcattttcag aacactgtgt
     1741 taaaatgtta ttacttatac ttataaagga ggggatgttt cgtgtcaaaa gcaacactat
     1801 ttgatagtcg tatcaaaaaa tacgcatact gtagaacatc agaaatttat cgagacattg
     1861 gctcatctcc ggatggttta tccattgagc aaatcggttc aatgcgggag aaatacggag
     1921 cgaacagctt caatgggcgg aaaaatgata cgacgatgca acggttgaga cgggcattta
     1981 ttaacccgtt tcatgtgatt ctttttgttc tgggcattgt ttctcttgtt acggatgttt
     2041 tcgtagcatc caattttgcg agaaatgcta ctaccgccat tatcatcttt tccatgatcg
     2101 taattagtgg cgtaattcgt ctgattcagg agctgcgagc aaagagcgct gctgctcagc
     2161 ttgatcgcct agttcatgaa agcgtcacag tgaggcgtga tggaaagtta atagagattc
     2221 ctggcgaaga attagtggta ggggatattg tactattctc tgcaggtgat cgtgttccgg
     2281 cggatatcag attgacgaag attacggatc tctttatctc tcaggctgcg attactggcg
     2341 agagcgccat cattgaaaag agctgccgaa aactcagtta cggagagcag gatacactga
     2401 ctcagcttga aaacctcgct tttatggcaa ccacagtcat cagtggaaaa ggggaaggca
     2461 ttgtactggc agtaggcaaa gataccctgt atggaggatt taccaaaccg gattctgatg
     2521 ataaaaattc ctttaaaaaa ggagccgatt ccatcgcctg ggtgatgata cgttttatgg
     2581 cgatattagt tcccattgta tttatattac tggggattac tgatggaaaa tggatggaat
     2641 cttttgcttt cgccctgtca gttgctgtag gtctgatgcc ggaaatgctt cctatggtta
     2701 ttacagcctg ccttgccaaa ggaagtcttg ctatgagcaa aaagcagacc attatcaagg
     2761 atattaatgc catgcagagc tttggtagca tggatgtgct ttgtatggat aaaacaggaa
     2821 cacttaccaa tgaaagcatc ctgctggaat attatatgga tatttttggg aatgaaaatg
     2881 cagaggttct tgatcttgct tatctgaata gctgctatca ttctggtgtc tgcaatacca
     2941 ttgataatgc cattcttgcc tgcaatacca tgccagggcg ggaagcccat tacgcaaatc
     3001 ttctgacaaa attccaaaaa gctgatgaaa ttccctttga ctatgctcgt aagtttgtca
     3061 gtacacttgt acaggatagc aatgggaata gtcagcttat tatgaaaggt gatattgaac
     3121 atatattctc acgctgcaac catgtagaat atcgtggaaa acttctcccc atggggcagg
     3181 atgcgagaca gagtgtatct tctgtagtag gtgaaatgtt acaggacgga atgaaggtca
     3241 ttgcggtggc acgaaaaaat gtgggagcgc aaaagaaaat aactcctgat gacgaatggg
     3301 gcatgactct agttggctat ctatccttct ttgatgcacc aaagcagaca gcaaaggagt
     3361 ctgtaactgc actcaaaaga ttaaaagtta tccctaagat tctgacaggg gaccaggcag
     3421 cgattgctgt gtctgtttgc cgccgggtgg gtatttatac agagcgtatc ttaactggta
     3481 ctcaactgga tgaaatgaca gactgtgaac ttaaaaaggc tgtggaacat actcatgttt
     3541 ttgcagagct tactccggga cataaggtgc gtcttgtctc tgctatgcag gataatggtc
     3601 attccgtggg atttcttggt gatggagtca acgacattcc ggcactgaat gaagcaaatg
     3661 tgggaatctc tgtagatacg gcagtggacg cagcaaaaga tgctgccgat gtggttttgc
     3721 tgcaaaagga cttgaatgtt ttggagcaag gtgtaatgga ggggcgaaaa acttttacca
     3781 atatgctgaa atatattaaa atcaccgcta gctctaactt tggaaatatt ttttccatca
     3841 tttgtgccag tgccttttta ccgttcctgc ctatgacttc aattcagatt ctgcttttga
     3901 atctgctgta tgatacgttg tgtattgtgc ttccttggga caatgtagat gaggaagaga
     3961 tgctgtcccc aagagactgg tccggcaaaa cactgagaca gtttatgctg tctttcggac
     4021 cgatcagttc tctgtttgat attgtcacct tcctattttt gtattatttc ctatgtccga
     4081 tgctatgtgg aggggcaacc tatctgcagc ttacagatcc ttccctgcaa cttcagtatg
     4141 tagcactgtt tcagactgga tggtttttgg aatctatgtg gacacaggtt ttgattttac
     4201 attttctgcg aacttccaag attccttttt tccagagcag ggcatctgca ccggtcattt
     4261 ctataactct agtggggatt attgctttta cttcccttac atttgtcggc ggtgcgtcgt
     4321 tgtttggact gacgaaatta cctctttggt atttcgtatt tttactgctg gtggtatctc
     4381 tctatatgct gctgaattca gtagccaaat atttttataa gaaaaaatat caagagttga
     4441 tttaagagga ggcattcatg atgaaaaaga atattagtta tattccgatg gattcggctc
     4501 ttgaaatctg gctattagaa aaactactaa gagatccacc ggacagtgat tgtgcgaagg
     4561 atttactttc tggtattcag gagatgattc gtggagaggt atcttcgtta ttgttaggag
     4621 catcagaaga aagcgattgg ccagtgggta ctctgtcaga tagaatcctg gcaggggatc
     4681 tggaaattta tccaagaggc agaaaagtac tgataaaagg ttctgaagtc aacctgactc
     4741 caaaggaatt tgatattttg tactttcttg tccagaacaa aggtgaagtt tttacaaagg
     4801 aacagattta tcgtgccgta tgggaggaag attatattct ggataacagc aacattatgg
     4861 cttttatccg gaagttgcga aaaaagattg aacctgctcc ggattgtccc acatatattt
     4921 tgaccatctg gggtattgga tacaaattta atgatcagat atgacaaaga cggactaaga
     4981 ccattttcgg tttcagtccg tctattttct taccaaatcg caagaaaatc gcaagacttt
     5041 agccatagga ttgtatttgg attttttata tactgttagt agttaaaggg aggtgtttca
     5101 tatgttttac acagatttta ttttgagaat tgccctctcc ttaacacttg gatttcttat
     5161 tggattagaa cggcaattga ctggtcatcc tgcaggtatt cgtatcaatg tgttaatctg
     5221 catgggtaca agtttcttta ccttgtttcc tatgctctac ggttcggatc aggtattccg
     5281 tgtcggaagc agtattatat ccggtgttgg ttttttatgc agtggtgtta ttttcaagga
     5341 cagagggaca gtacgtggaa tgaataccgc tgccacctta tggtgtactg cagcgattgg
     5401 aattcttgca agtacgggaa tgtatgcaat ggcgatcacc gccgctacta ttttaattgg
     5461 ttccaacctg attctacgtc cctttgcaag aaagtttcac ccaattactt ccagtgatga
     5521 atctgaaaag cagtatcgta tttcggttac atgtcaggaa aaggcagagc aggatatacg
     5581 cttattgctg attaacagca attcctgtaa gacgctcttt ttgaacaatc tggaaagcgg
     5641 tgatgtggtt ggtgacaagg ttgagattgt cgcagaatac tgttctgtcg gaaaatccaa
     5701 aaacaatatt ttagaaggaa tcgttgggca ggtattggta attccggaag tgattagtgc
     5761 tggttgggag gtgttgtgag tgaggagaga aatcgaagat ttgaaacgag caattctttt
     5821 tgctttctac cctgtattta caatcttatg tagctatttg ggttggaatt tctttgaaca
     5881 aagaatggta atctttaaga tatggtatca ggtgagtatt gtgatctggt ttattcttgc
     5941 tgttactatt attgtgctct tcattaaact tctgaagctg acaaaactaa gaaacaggtt
     6001 taagcattga aaggaggaac aaacgatgga ttttacatgt atcttttttg gaattttatt
     6061 tactcttgca ggcttttggt tggcctttgg aaaaggatat cgtcatcttt ccctgtggaa
     6121 aaatatgccg caggaggaga aagataaaat taatattgtc ccgctttgtc gtaatgttgg
     6181 agaaatgatt gcgttaaatg ggattatatt cttaatgaaa ggatttttgc cgggattttc
     6241 aaaccactgg tttgtatttg caataatcgc atggctgatt gttgccggct ttgatgtctg
     6301 gtatatcgaa aaaagtgtcc gctatcgcaa ccaataatcc acattgaggt ttcacataga
     6361 tattttttta agattgtgag gtgaaagaca tggactctga tgtcagtcca cgaaggcaga
     6421 gaatattata tgagaatttg gagattccgt gtcgctcata taatattcct tgcccctatg
     6481 aaaattcaag gaggtaagac caatgaacaa aaaagaaaat cgtatggcta ttcgtcagac
     6541 tgtagaaaaa gcagtcatcc gtgacgaaca gaaccgccgc attcaatttg cggcaaccaa
     6601 tcctattaaa gaagttttaa aaaaacttca taccacactt cgtggcttag aagtagatga
     6661 agtatccgta agtcgtgcta aatatggtac caataaagtc actcatgaaa aaaagaaatc
     6721 tctggcaaaa cgactggttg gcgcatttat caatccattt accgccattt tattttgtct
     6781 ggctttagta tccacaatta cagatatgat ttttccgtat ttttctctgt ttggcagtgt
     6841 gccagaggac tttgattccc tgactgttgt aatcatttta acaatggtat tcatttccgg
     6901 tacgcttcgt tttgtacagg aatccagaag cggaaatgca gcagagaaat tgttagccat
     6961 gattacgacc acttgtacag ttactcgtag aaactatgaa aaaaaagaac ttcctatgga
     7021 tgatttggtg gtgggagata ttgtgcatct ttctgctgga gatatgattc cggcggatgt
     7081 tcgtattttg gatgcgaagg atttgtttgt cagtcaggca agtcttactg gtgagagtga
     7141 acctattgaa aaaacaccca atgtaagtgc tcagaaagaa agcgtgactg attacacaaa
     7201 cattgctttt atggggagta atgtaatttc tggtagcgca acagctgttg ttgtttgtgt
     7261 tggcgatcat actctgtttg gctctatggc gtccgcagtt gctggagaag cggttgaaac
     7321 aagctttacc aagggtgtca atgccgtttc ttgggtattg attcgtttta tgctcattat
     7381 ggttccgctg gtgttctttg tcaatggtat caccaagggc gattggttgg cggccttctt
     7441 attcggcgtt tctattgctg ttggtttgac accagaaatg ttgccgatga ttgtaacaac
     7501 ctgtcttgcg aaaggcgctg tttccatgag caagaagcag acaatcgtta aaaacctcaa
     7561 ttccattcag aacttcggtg ctattgatat tctctgtact gacaagactg gcacgctgac
     7621 ccaggataag gttgtgctgg aataccatct gaatgtaaat ggcgaggacg atacgcgagt
     7681 actgcgtcac gcttacctca atagttactt ccagactggc tataaaaacc tgatggattt
     7741 ggcaattatc cataagacgg aggaagagga agccgcagat tcgcgtctca ttgacctgtc
     7801 tgaaaactat gtgaaagtag atgagattcc ttttgacttc acacgtcgtc gtctgactac
     7861 agtggtacag gataataagg gtaagaccca gatggtaaca aaaggtgctg tggaagaaat
     7921 gctctctatt tgtgcgtttg cagagtgtaa tggaggagtg cagcctctga ctgatgacgt
     7981 tcgttacaga attctggaga cagtggacaa tcttaacgat aagggattcc gcgtactagc
     8041 tattgcacag aagagtaatc cttccccaat cggcgcattt ggtgttaaag atgagtgtga
     8101 tatggtactg attggatatc tggcattcct tgatcctcca aaagaatcta ctgcggatgc
     8161 tattaaagct ctgaaagacc atggtgttat aaccaaaatt ttgacaggtg acaacgacaa
     8221 agtgactcga actatctgca agcaggtggg attagaggtt cgcaatatgc ttctcggttc
     8281 tgatttggaa caaatgggcg atgcagagct tgcaagagtg gcagagtcta cagatgtatt
     8341 tgcaaagcta acccctgatc agaaagcccg tgtggtttct gttctccgtg aaaatggtca
     8401 tacggtcggt ttcatgggtg acggtattaa tgatgctgca gctatgaaag ccgccgatat
     8461 tggtatttcg gtggataccg ccgtggacgt ggcaaaagaa tctgctgaca ttattctatt
     8521 ggaaaaagat ctgatggttt tggaacaggg tattattgag ggacgaaaga catatgccaa
     8581 catgatcaag tacattaaaa tgactgcttc atccaacttc ggcaatatgt tctcagtgct
     8641 tgctgcatct gctttgctac ctttcttacc aatgatgagt gttcatctta tatttctaaa
     8701 cttaatttat gatttatcct gtactgcaat tccttgggat aatgtggatg aggagtttat
     8761 taccaaacct cgtaaatggg acgcttccag tgttggaagt tttatgatct ggattggacc
     8821 aaccagttct atctttgatt ttacaaccta tatttttatg tactttgtat tttgtccatt
     8881 gttcgtatcg aatggtgtat tatttaatga tttgcctgct catttcagcg gtgcagaact
     8941 ggcaatgctt caggcacagt atatcgggat gttccaagca gggtggttcg tggaatctat
     9001 gtggagccag acattagtca ttcacatgat tcgtactcca aagctacctt ttgttcagag
     9061 tcgtgcatca gctccggtga ctttgctaac aatgactgga attatagttc tgaccattat
     9121 tccgtttact gtgtttggaa ctatgcttgg atttgttgca ttgcctgcag catactttgc
     9181 ttatctgatt ccatgtattc tgctgtatat gactttggca acaagtttaa aaaaagccta
     9241 tgtccgtcat ttcggagaac tgctttaagg aggtggaatg atgaactgga aagaactttg
     9301 gatgaccctt tttggaacta ccgaatggct tggtcttaat atcggctttt gggtggctat
     9361 ggcagttgtg ttgctgattg ttattgtaat gaatgtagta ttttggtcca tgaaaccaaa
     9421 aaaagacaca aaagagtctt ataaataaga tatcagtatg aatgaatcaa gggagatgca
     9481 cagtttttta ttgtggaatc tccctatcat atcaaggcgc attcaattgt ggcaatttag
     9541 tagtaaagta tgtgtttttt tatcattgaa ttacctataa atgctgtata taagtggata
     9601 attgtaattt cgatataaaa attatggtac ttaaaagaaa tttcgttttt tattgtttgt
     9661 ttacgcgtct ataacgaaat cgtgaaataa tattcaaagg tagattttat tatggaatgt
     9721 atgtctgtag aagaagcttc gataaaatga ggagatatct gaaagaagga taaaaaaatt
     9781 atgtaatgga aacagaatcc caaatctatt gtaacaacaa tgacaggtaa tgaatggtta
     9841 cgtagattga taattcctat tcaaattatt atctatctta tattgagtgg tgttttgtaa
     9901 ttacattttt atacaaaaag aatatgttga acgcacaatg ataaatattt tgtattcccc
     9961 aactaataga ataaagtttt tgcttggaaa gtatgttata taggcattat ggtttgtaat
    10021 gatcacgttg acagattata ccgctatata tgaagtcaaa gaacttaaat catttacaag
    10081 tgagataatc tatctaagtc taaaaaactg gatttctcaa tctattgtca atgagtccat
    10141 tacttattat ttgtgttttg caaagaaatg ttttctactc tagtttactt tttagttact
    10201 aaatatcggg aattggtttt gttggactat attgatctga aagtatacaa aatattattc
    10261 cgtggtctgc tgtaacccct ataagtttat tagatgcaca aggattgcta ccttatattt
    10321 caattctact ttgttatttt gcaagactga ttataaatac atactgcttt agagggttta
    10381 gtttagttct ttttgaactt ttgaataaga cgacggttat atagccgccg ttttattttt
    10441 gcctaacgtt ggacaaatta ctggatggtc ttgttttatc ggctctaggg gtagccgtat
    10501 gaaacactta catattcaac aactttcgac catcggtagt tcattaaaaa aacatttaaa
    10561 ttctacggaa cataatgctc ctatatgtgg ttttttacag catataacag gaataatttg
    10621 tttagcacaa gatcagtacg tctgtattgc ccttgtgctt ttttactgca taaaactttt
    10681 tcaaaaaatt tttgcggttg ggtatcaaat cccacctttc atggtgagtg ttagtgcgaa
    10741 aagaggtaga agtcttttcg ctttagcaac tttcgctgga aagggggtga gattatgaaa
    10801 ccatcttctt tcgagggcgc tatcagactt caatttgatt gtctagctcg caaggttgta
    10861 ggacgaactg taaagaacta tgaccgagag cttggcagac gtgcaagacg tgaaacgccg
    10921 ttctgtgatt tatctgaaat ggagttaaac cagatcggtg ccatggacga atattgcgtt
    10981 gagtttacgt catttgatgt atttggttca gaagtccata tctatgatga acgcttatgt
    11041 gaagctatca aagaattaac agaaagccga cgtaacattc tgcttatgtc ctactttctt
    11101 gaaatgaccg acgctgaaat tgcagaggtt atggaaatgg aacgattttc cgtatgtaga
    11161 aacaggctgc acacattaaa gcttattaag gatatgtacg aggaggaata aaaacatgat
    11221 gaagtctaca aaaaagtgtc catcattctc gaccatcagt tctgcagctg acggtaacga
    11281 ggtggcaatt gaaaagattt tgaaccatta tgacgcttac atatcaaaag ccagcctacg
    11341 cccgttctat gacgaacacg ggaatatgta tatcgtgctt gatatggaac tgaaaggcag
    11401 gatacgggca gcgttgatta aagtaatctt agggtttgaa gtcaaagtga agtaaatata
    11461 acagagagta tctaccacct cattttaact cttttccgtt ctttgacaag tgaatacagt
    11521 aatcagatac gtttgatata cgacgagcca gcggactgga acgccacgac cactgaaatg
    11581 gggaaagcag cgagcgatta tgccagtgaa ccgcaagcga tctttggaaa ggttgctgcc
    11641 atgactcgta tatctgaata atgatacacc cgtatgacac ggttcaccca tcagaatggg
    11701 aatggtgaaa gtccagtgga gctgccgaag ccgtctgatt acttccataa ataaaaaagc
    11761 aaggagggtt ttaatgaata atataattag gtatagtatg caaattgcta tgttaaaaca
    11821 actgcttgcc cgtaaactga tttctgaaaa agaatacact cttgtaaaac aaaggctgat
    11881 gaaagactat aaggtgcttt ctgacataac tgcttgaatt gtgtttttta aagtagtaca
    11941 ataacaatat gaaaggaaca caaaataagg aggtgtacta tgcaggaagt tgaagtaata
    12001 aaagcaaaaa atgttttggc aagacaagcc cgtggaaaag ccattgagcg tttgcgtgta
    12061 gctacatatt gccgtgtaag tacagatagc gaagatcagt taaacagtta taaatcacaa
    12121 gttcagtatt atactgacat gattaagaaa aacaaggaat gggtgttagc tgacatttat
    12181 gctgatgaag caattacggg gacacaagta acaaaacgag aagattttca gcgtatgata
    12241 aatgactgta tgaatggtga aattgacatg gtatttacaa aatccatatc aagatttgcc
    12301 agaaatactt tagacacatt gaaatatgtt cgtatgctaa aagagagaaa tatcgccgtt
    12361 tattttgaag atgaaaaaat caatacactt acaatggatg gagagttatt gcttgttgtt
    12421 cttagttctg ttgcacagca ggaagtcgag aacatttcag ccaatgtaaa aaaagggttg
    12481 aaaatgaaaa tgaagcgcgg cgagctggta ggttttcaag gttgtattgg atatgattat
    12541 cacccagagg ataagacaat aactgtaaat caagaagaag cagagattgt cagatatatt
    12601 ttcaaccgtt atgttgatgg tgctggtggt tctgttattg gacaggagct tgaaagtcta
    12661 ggttataaaa cgaagtatgg gagttccaca tgggcaccat ctacggttat tggaattatt
    12721 aagaatgaga aatacaaggg tgatatactc ttaggcaaaa cttttactgt tgatccgatt
    12781 tccaaacgtc gccttgaaaa catgggtgaa gaagataaat tttatatgaa agatcaccat
    12841 gagccgatta ttagtgaaga agtttttgaa aaagcacagg aaattcttaa tcggagaaat
    12901 aagaaccgaa caacggtagg cagcggtaag cgtgagaagt atagcaggaa atacgcattt
    12961 agctgtatgc tagaatgtgg cttttgtggt ggtactttaa caagacgtaa ttggcacagt
    13021 ggctcaaaat acagcaaggt tatatggcaa tgtgtaacgg ctacgaagaa aggaaagaaa
    13081 ttttgtaaac atagcaaagg tattccagaa acagctattg aagaagcatt tgtagaaagt
    13141 tatcgtttat tatgtgatga taataaagat gttctggaag aatttttgca gagaatggac
    13201 gatactctta gtagtagtgt ggtgtcaaaa caacttgcaa aagcggaaaa ggagatagac
    13261 gcattagaga agaaaaaaag taaacttgtg gatatgcgtc tggaagaaat tattgataag
    13321 gaaacctacg aaagtaaata tgctgattta gtaagtaaac aagaacagct tgttgaagaa
    13381 agacaaaagt tacaagaaac ttctgataat gagaaagaca taaaaaaacg tttgaaagag
    13441 tttaagaaaa ctctggaaca gaatgaggtt cttgataaat ttgaccgcta tgtgtttgaa
    13501 agcattgttg aaaaagtaat tgtaggtgga cttgatgaaa acggaaatgt tgaccctgca
    13561 cagttgacct ttgtttataa aacaggcttg aagaatagcg tagatggtgc taaatttaaa
    13621 acacaaagga aaaatgcaag aggacggcat aggactaatg aattgtgttc acatgacagc
    13681 aacgaggttg ataaaatgtg ttccgatagt agtaacgaca catgtggaaa ctgtagctaa
    13741 gataatcaaa caatagtaat gtttatatag attatatact aataatatat tgtatttgcc
    13801 accgatttgc cactgtaaag cgatttcggt ggcaaattta gtctacaatg ttatcaaaaa
    13861 tctctaaagt tttattttta attctataaa acttattata attgtaattt taaaagaaat
    13921 agtcaatcta cagtagccag attttataca actcattttt ttcatagagt aatttacata
    13981 atctatagtt gaatattatt taatattttt ataattcatt agcaaatata ggcattacaa
    14041 atgttgataa acatgtgaaa gcacatatcc acttataatt atttttttta aaaccataaa
    14101 atcacctctt catttgttgt atgtttttat aacaaatgaa gaggtgattt ccagacaatt
    14161 taaaaggttt ttgtatattg actaaaattt atttttatta tttataattc ttaataatac
    14221 atatgtacct actgattcca tattaaactg tataattttt gttcatcttt ttttataatt
    14281 aaaactacgt agttctcata atttctctta tatatatact tatcatcttt tttaacttct
    14341 aacttatatt ttttaaaatc ttcttcaatt ttatttttat tacttttatt aatgttaaca
    14401 gaatctcttt taaatttatc aatatatttt tctatttcat taatattatc tttgcttaca
    14461 actataccac cttttaaatt aaaaactttt ttgaaatttt tttcagaaaa tccttgaata
    14521 aaataacttt gtccatctcc attaatacta tcttgagtat caaatacttc aatttctttg
    14581 ttaggtattg gtatatcaaa attccaagat tcctttagca ttgaaatatt agctgttttt
    14641 cctaaaaaaa gattatatag gatacttcct aataacaaaa cacctattaa tagtagtgtg
    14701 attaatacaa tttttctctt tttcattttt cgttcacaac cttttgaaaa aacatgattt
    14761 aattcatcat ttgaaggcat gtcttcaaga ataatttttg ttgtgatagg aatgctttct
    14821 tgaaacatat catttgtaat atcaaaatct tttctttgat tactcaatat ccatttcttc
    14881 taatatttct tttgattttt tctagtacat tgaatactct tatatacatt ctcctctttt
    14941 aaaattaaaa gttataaaag aataagttat ataaaaaatt attatatttt ttaatatagc
    15001 ttatttgcaa atttataatt ttgttaatct aatccttcaa actaaaaaat catttatatt
    15061 tacagaattt cattttaaga gatgtttatt ttcacataga taagagaatt taagttctca
    15121 tatttattat ttgatacaaa tttacatctt tattatatgt attttaaata aaaaataaaa
    15181 ttatgaatac tagaaatcta tcttaattag ctttctaaca taaggctatt taaagtagat
    15241 aaaactaaaa agggttctct agaaaaccaa atctatttaa ttatacttac ttactaatac
    15301 catcacttga tgcaaacaag attctaccac attttctccg tactctagta taaaatcatc
    15361 tagttgtgta tctataaaat cacaataatc atatgaacta ccaatataag cagtcaacat
    15421 atgtgtacat ctatccattt tatctctaaa catatatatt attatccccc taaaaaactt
    15481 tcataaaaac aaaaagaata tctctttttg gcaactggct gacataactc atagtttatt
    15541 ttataagcgt tagtccctat agctttgcgt cactaaattt ctctagtttt gccgatttag
    15601 ttttattcta caattacaat aatacaatag aattgcttat tattcaatat acttatttga
    15661 aaattaaata aatttacaaa tatgaacgtt attttatatc aaaaaaaata gactatgcat
    15721 gtagaatata tggaaaaact tgattgtagg ttttgtatga aaagacagtt gttattaatt
    15781 taagtgagat aaattgagca acaggcataa aatgagaaaa caaataatag cagttaattt
    15841 ttattattaa tactaggtga acattaaatt tcaaaatacc actagatttt atagaataag
    15901 aaaatgagac aaacataaat atatgaatat attaaattat acttgaacat acttatattt
    15961 tatgataaaa tttcaataat aattattagt gaaggagtgt cttgcctgat gtcagagtta
    16021 tatataatgg taaccaacaa ataaatagtt ggagacgcat atgggttctg tttaatcaga
    16081 atttttaagt gtatttttga tacatttgat tgttgtgtct tactctgcct ttatagataa
    16141 ctaacattag acaacaaata ataatattac atattacttt gttaaattgt ggtgtagtgg
    16201 gctttaatct gctacacttt tattaatttt acacagtatt attttgaata taattatgtt
    16261 gaaatagaag atactaaatt ttctagtcca caggggtttt ctgtttttgt gtaggtaaat
    16321 atgtatacca cataaaaagg cagatataaa tacctgtgga ctttttttgt agaaaataca
    16381 cgatacggag gaaataaaaa tgaattataa aaatagaaaa cgagcttatt atcaggaaaa
    16441 ttcctgtatg gataacttta tttgcaaaaa ttgtggttgc cttgtagttc ctgaaggagc
    16501 tggtacacaa catagaaatc attgtccaca ttgtttacat agtcttcatg tagatatcat
    16561 tcctggtgac cgtgctgcag attgtgatgc taatatggaa cctattggag tgtgggtgag
    16621 aaaaaatggt gagtgggcaa ttattcatcg ttgtacacgc tgtggacatc ttagttctaa
    16681 tcgtattgca gctgatgata attcagtgaa attaatgtca attgcattaa aaccactggc
    16741 acagccccct ttcccactag aaagaatcat tgaaaagttg gaaaaggagg aaacagaatg
    16801 aatggtatga aacaaatcaa tttacaagac tatggtctaa atagaaattt tattactcaa
    16861 agtatggaat atcatgattt ataccttgct cggattatct cgcaggaaaa gaacttttat
    16921 caagctgtat gtgtaaatgg tgtactgttt gcagaggttt caggaaagct gcgttttgag
    16981 gctactatac aatctgattt tcccacagtt ggtgatttcg ttatgttgga tcgttgcaat
    17041 aataaaaatg gtaatgctat tattcatcat gtgcttcata gaaaaagctt gtttgtgcgt
    17101 aaggctgctg gaaaggtaaa tgaggagcag gtggttgcag ctaatattga cattgttttt
    17161 ttgtgcatgt cactgaataa ggattttaac attcatagat tggagaggta tctgtcttta
    17221 acatgggaaa gtggagctat cccagtagta gtacttacta aatcagactt atgtgacaat
    17281 gtgcatcgta aattacaagt agttaattct atagccttgg gtgtagatgt agttgttacc
    17341 tcatctatag agccagatgg ttataaacag atttctaagt atattaaacc aggctgtact
    17401 gttgccttac ttggttcttc aggagttgga aaatcttcat taattaattg tctgatgggt
    17461 ggagaatttt taaatacaaa ggaaattcgc atagatgatg ataaaggaag acatgccacg
    17521 actagacgag agctattttt aatttcaggt ggtggtattg ttattgacac accaggtatg
    17581 agagagttgg gaatgtggga tgtttcagaa ggtttagata aaagttttgc agatatagaa
    17641 gcttatttcg gaaaatgtca ttttcgtaat tgtactcaca cctcagaacc aggctgtgct
    17701 atctgggaag ctattgctca tcaagaactt tcgcctaaaa gatgggaatc ctatcgtagg
    17761 cttaaaactg aagcagtatt tgcagacaat aaaagcgaat acttagcaaa aaaagaaaag
    17821 aaatttaaaa atatctcaaa aataaataag aagattagaa gataagtgta gtttttttgt
    17881 tcattctatg agtctatata ctattaatat attaaatttg ccatcaattt gttactttaa
    17941 tgtgattttg atggcaaatt tggtttgtgg tattatttaa agcaatttat taattttttt
    18001 aataaagttt gattttttat atgatgatat atacatgtga taatgtatac atatttgtta
    18061 cgataggctc ctttataaag aggtcttatg taagataaga aaaggcatat ttatactaat
    18121 acataataga gtatatgctt atgtatgata gagatgtttc ttaagagcaa aactgcaata
    18181 ttgctaattt ataaagtaaa aatatatgaa ttataaaata caaataatat atttataaaa
    18241 attattgttt taatttataa taaaaatttt ttgttgaaaa taatgctcga acctataaaa
    18301 ctattaacta atatttgtaa atgtatactt ttgatgataa aatataatta agttaagttg
    18361 gtttttataa acataaattt attttaagga ggtgaaataa atgaaaatat ctagtcaata
    18421 tagaagtcaa tattcattta gatatgaaag taatataaat aatacaagaa taaatgaaag
    18481 tatggttaag aaaaatgaaa ctgtaggaaa agacacttat ttatctaata ttatgaaaca
    18541 aaagcaagaa cttaatgata gaattagaga tttaaaatat agacaagagg tttatactaa
    18601 aaaaataaat gacgcaatta agaacttatg taaatcagaa ataagagaaa caactaataa
    18661 tttttctaat atagaaatag gtattaaaaa tagcattata gaagagaaaa ataaaagtac
    18721 aatgttagat gaaaattcaa cttatctaaa tacaaatgat gaaaaagaat ctttaatcac
    18781 taaagagtct aatgaaaaaa ttgaagaaga aatattaaat gatgaaaaat tagaagagtt
    18841 agaacaaaaa aaggattata aagaggattc taataaaaaa gagaaagtat ctgaggactt
    18901 atctttagta ggtaaaactc gtgaagagct tgaaaatatg cttaaaaatt ttataaattt
    18961 aacacaagaa gaaataatga aacttgagtc gagaatagaa aagttagata aaaatgctga
    19021 agaatacaaa caaaattcaa agactaatat atttgataaa acagatgaac aaaaaaaaca
    19081 tataaatgta ctgatttaaa caatatgttt taaaaaaata agtttattat ataatgaaaa
    19141 tataaaggta caatttcaat acacttctat taaaccaata atttatgaat cagatttaat
    19201 ttcaatttac taataaccat atatttatga gttaataatt ttatgtttta aaaagaatta
    19261 aataaggggg agtagtatga agaagaatat attaactact atgattacca tgattattat
    19321 attgatgatg agtatgacag taatggcaga gccatatcaa gaagatgaaa catctagctt
    19381 gaaaaaacag agtgcaaatg aacgtaatca gactaatata ggcacaatgg atggcagagt
    19441 gcaaacaaat gcaataagta aaggtgctaa ttatgaccct aaatatcctc ttaaaggaat
    19501 gttaacacaa cttggtctta atacaacagg taaagaggga tgggatttac tctatggagg
    19561 aaatcccaat ggagttgagc ttcgagcaga tggtaaatat tattatataa ataagggtat
    19621 ggaagggcta ggattttatg cggcagcatt gtcaggtggc tcatatcaga gaataggctt
    19681 tggaaaactt gaccctatag aagtaatagc tgatggaaat tggatttctt acaaacaagc
    19741 tcaagataca cttacagtaa tcaggaattt tttaaatagc tttgactgga gaaatgcatc
    19801 tgagatggaa agagctaata gagctgcaaa attggtaacc gaagcaaaat atgcagactc
    19861 taaatattgt aacatagtct atggtaatct ggttgataaa cgtggtgtat gtggaagttt
    19921 tgcaagtagc tttcatttat taacaaggtt aatgggaatg gattcactat ctatattaaa
    19981 tccatcatta aatcatgctt ggaactatat acaaattgat gggaaatggt ataggtttga
    20041 tgggtctgaa atatcagctt ttggtggatc attagacttt gattaccgta aattaaagga
    20101 tgcaacaaga gagatgacta cttactatga tgctaaggca ttgtctatat taggatttaa
    20161 tcaataaaaa tagggggagg cttcttatag agcctttttt tattgatttg aaatttaata
    20221 aggaatttta tatgaaaatt taatcaataa aagcaaaaaa ggctctttat aaagcctttc
    20281 taagtgtttt tttaagtaaa attttttata tcaacatcag ttttaatcaa aacatataac
    20341 attttggact tacttttaaa aataaaatta ttaaaatata atattaatca tgtttttagt
    20401 ttattatatt ctataatagt ggtcatgttg actattgtag ttttattaag aatagttggt
    20461 ttatataaat atatgcaaag atagcttgtt gtttacttta cttattagta tataggacaa
    20521 gatactctaa taaatttgcc tattttaata tcttttgtac taaaaccaac taaagtttcc
    20581 tttattattt cgttttgaat aatacaaagc ataatccgat tgtttgtata aagactggaa
    20641 agtatcagag ttattttcta atttagatat acctatagaa caagaattac tctctaggca
    20701 taattctaaa accttctttg ccttattttc aacattctct tttgattgat tactatattc
    20761 aaaaacagca aattcatctc caccaagtct tccaataata gcatcattta cgaatacttt
    20821 agtcaaaata tttgaaaaat gtattagtat ttcatctcct cgaacatgac caaagatatc
    20881 atttacctgt ttaaaattat ctaaatcaaa gatgtaaaag tatccatgtg aaacagtttt
    20941 aagcatttct tttatgtgta cttcaaaaaa atgtctattg tatagtccag tcataaggtc
    21001 tttttctgat tttagtttaa attcatttgc cattgctagt gcttcttgtg ctttttcagt
    21061 tattgtttta gggtaatact catctttcat ttggtcaaag tttggaatag aatggtgaac
    21121 atggataagt ttaatcatat catctgtaac tctgtatacc atagtaaatc gagtatccat
    21181 ttctacatag atatcttttt ctaggtaatc tttttctatt acccaaagag taccatatac
    21241 tataaaagct tcgtctgtaa ctttggtaca tgaataccac tcatctataa tctcaaagtc
    21301 tatttgctct gattctgttt ggtctttttc aagacctata ataaattctt ctaatgtttc
    21361 gtaaaattca tgttttcctg ttccaattaa tgcaaggttg tcatctaata aggaaataat
    21421 aaatttaagg ttttcttctt ctggatttaa aatataaata tgccaaattt tttttgataa
    21481 atctcttaat tgtttttgta ttgtattatt ttccatagat taccccctta agatttacag
    21541 tttatatttt aatgtattat aagttgaact cttattacaa tattattata atatagaact
    21601 aaagaaatta catcctgtat aagtaaaagt atatctttta taataaaaat attacagtaa
    21661 aataaccagt tttaatatac gtattatatt tttaatttat aaacgaatat tataaatgaa
    21721 atttaaattc aaccctgaag aaataagcta aatgtattag tatataaatc catacttgaa
    21781 cataaataac ctttatgata tgatatcaat aataatatta tgagaggagt gccttgatgt
    21841 cggagttata taatggtaac caacaattaa atagttggag acacatatat tctgtataat
    21901 cagaaatttc aagtgtattt ttaatacatt taatttttgt gtcttattct gcctttatag
    21961 ataactgaca tatgacaaca aatagtattt aaaatatata ttactttgtt aaattatggt
    22021 gtagtaggct ttaatctgct acacttttat taattttgta tagtattatt ttgataacta
    22081 ttttgaaata gagagcatta atttttctag tccacaggag ttttctgttt ttgtgctgtt
    22141 aaatataagc acagagaaag gcagatatat acctgtggac tttttttata taaattatga
    22201 aatatggagg tagttaaaat gagtataatt gaacttaatg aactgactaa atcttataga
    22261 agatttgaga aaaaggcagg atttatgggg agtgtaaagt ctttatttaa taggaaatat
    22321 acagaaaaaa cagctatatc gtcatttgat ttaaagatag aagaaggaga atttgttgga
    22381 ttaataggtc aaaatggagc tggcaaaact actcttatta agatgttaac tggtattatt
    22441 gcaccgtctt ctggagaaat atctgtaatg ggttattacc ctaacaaatt agaaaataat
    22501 tttaaaaaac aatatgctgt tgttatgggc caaaaaagtc aactattctt tgaattgaca
    22561 ccagcagata cgtttctttt atttaaagaa ttatatgata tatctaatga agaatataag
    22621 aaaaacttgg attactttat cgaattattt gaggtatctg actatttaaa tgttcaagtt
    22681 aggacgcttt ctttaggaga aagaatgaaa atggaactaa tagtagccct tctacataat
    22741 ccaaaaatat tatttttgga tgaaccaact ataggcttag atgctatagc ccaaaaacaa
    22801 attaggtatt tcctaaaaga agtaaatgaa acaaaaggaa ctactattat acttacttct
    22861 cattacatgg aagatattaa gagtctctgt agtagaagta ttgttgtaga aaatagccgt
    22921 aaaatatatg atggttctac agagaaacta tttaattatt ttcaaaaata taaaaaaata
    22981 acagttagtt tttccaatga aactaacatt gtatttccaa aagattgtaa agttgttgaa
    23041 caaacaaatc ataagatatc agtaattgtg ccaaaagaaa gaggaaatga aacgattaaa
    23101 tggatttttg ataaatatga tgttaaagat gtaatgattg aagaagaaga tataggtagt
    23161 attgtagaga ggatatataa gaaaggaagt gatgagtatt atgagcaact ataatgaagc
    23221 aagttcaaat gattcaatgt tttataaatt taaacagagt attagaaggt attatgaagt
    23281 agccaaaatt aactttaaag tgcaacttat ctggagattt gatgtggtgg ttaatatggt
    23341 gtttacgatt gtaaaaattt tatttgctta tattttatgg aaagcaattt ttggtgaaaa
    23401 taaaatagtc tctggtttta catttaactc tatgttatct tactatataa taagctcatt
    23461 tttagcaggt attgatatgt caaagagtac cagtgaagag atatgtaatc gtgtaaaatt
    23521 gggcaccttt tcaaagtaca tgattattcc aattaatgtt caaaattatt ttattgctaa
    23581 aaattttgga atgacatgtt tttattttgt atttaatatg atttctgcat ttgtatggat
    23641 ttttatattt aaaatagatt ttgcctttac atcaaatcca gttcaaatat taatttcaat
    23701 tttgatgatt tttctagggt ttatttttat gatgaaactc cacttcttta ttgggatttt
    23761 gtcatttaaa tttcttgaga ttagtttttt taaaatgata attgaaaata ttgttgaatt
    23821 tattacagga acaatgatac cacttgtact cttaccagaa actatagtaa cagttatgaa
    23881 ggtatttcca ttttattata caacatattt gccatctatg ttactaatag gtagaaacag
    23941 caatgaggca atacaaggat taattattct agcattatgg gttttatttt tttctgtagt
    24001 aaataaagtt atgtataaaa gaatgagaac attatttgat ggggtgggta tatgatgaaa
    24061 aaaaatttga aaataatatt tatgttatta aaaatgaaat tatcaaagat gatggtattt
    24121 agattcgatt tttttggagc attttttgta gatagttcat tatttatatt acaacttcta
    24181 atgtttaata gtatatattc tcatgtagac tcaatagggg gatggcaaca aggagagatg
    24241 ttaatattta taggaacttt ctcattaata aatgcgataa atatgacgat tttctttttt
    24301 ggtatttatg atattccacg aaaaatccaa gaaagagaat tagactacta tattacaaaa
    24361 ccattagacc cactatttag gttaacattt gaaaatatta atattggttc atcaccatta
    24421 attctagcaa gtatacttat tgttttatat ggaatatctg agttaaactc agagataact
    24481 ttagttatga taataatata tattttcatg gtgttattga tgacattact tttttatgat
    24541 gtatgtatca tacttagaac agtttcattt tttgttatat catcttctgc gataatgaga
    24601 ttagaagata atttattgcc aatgaatatg aaaattcctg gtgtaatata tgaaggtatt
    24661 tttaaagtat tattctattt aatcttacca tatggaatta tgtcgacaat tccgactcaa
    24721 attttggctg ggacaataac aattaatgga ttaatatact caattttaat tgtatttttg
    24781 tttacattgt ttatgtggag attttggaag ttaggtatga gacattataa aagtgcaagt
    24841 agttaataaa ttagtaaaaa tagacaatgt ataactatat ataaatacgt ttcatatgac
    24901 actaaactat gtgaacaagt atttgcgcta aaggcactga aagctataaa atgattaaag
    24961 taaggattta aaagtttctt tagtagaaat ataattgtgt aaaaaagcaa gattaattaa
    25021 aactatatcc aaataattag atataattct tatgcagaaa ggaggtctgt aaatgtctaa
    25081 ttgtttggaa tatattttaa aaataattaa tgtacagaaa aataaacaaa atgagtgatg
    25141 tatattattc agaaaatcat gaacaagata atctttatga gcaagataat ttactggcac
    25201 aaagatttaa tttatttact ctattgaagt ttgcatttcc tactattttt atgatgattt
    25261 ttatggggtt gtatacaatc gtagatacta tatttgtatc aagatttatt aatacaaatg
    25321 ctctatcagc aattaatatt gtatgtccaa ttattaatct tatagttgga attggaacta
    25381 tgcttgccac tggaggaagt gctattgtag cacgtaagat gggaaatggt gatattgagg
    25441 gagcaaataa agctttttct ttaatcgtat tatcaggagt tgtaattggg gtaataatta
    25501 ctggtatagg tattgtattt atggattata tcattatatg gttaggagca agtgaagttt
    25561 taattaaata ttgtcgttca tatcttttta ttatcttggt ttttgcttct gcaaatatac
    25621 tacaagtatt atttcaatgt ttatttgtaa cagctggaaa gcctcaattt ggattatggc
    25681 tagtgttagg tgctgggtgt gctaatataa ttcttgacta tgtgttcatt gttctgttac
    25741 aaatgggtat tagtggagca gcacttgcaa ctggagtagg atacctaatt cctaccattt
    25801 caggtatggt tttcttttca aaaaataaag ggttacttaa attttgtata cctagactag
    25861 ataaaagaat attatttgaa gcttgtttta atggttcatc tgaaatggtg ggtcaactat
    25921 caacagcagt tactactttt ttatttaatg ctatgatgat gaaattaatt ggtgaagatg
    25981 gggttgcagc tattacaata attatttatt ctcaatttct tttaacttcg ctttatatag
    26041 gtttctcaat gggtgttgca ccaataataa gttataacta tggaagtgaa aataatacgc
    26101 agttaaatca tgtttttaag atttgtatat tatttatttc agtagcatct ttattggtat
    26161 ttatcttttc tatatcatgt tcaccaatca ttgtagagat tttttctcaa agaggaagcc
    26221 gagtttatga aattgcaagg tccggatttt atatattttc ttttagtttt attttttgtg
    26281 gatataatat ttttacctca tctatgttta cagcattatc aaatggaaag gtgtctgcaa
    26341 tattatcttt tctacgtaca tttggattta taactatagg tttattgata ttgccaaata
    26401 tattaaatat aaatgggata tggttagcag taccaagtgc tgagatttta accttatttt
    26461 taactgtttt ttgtatattt aagtataaga atagatataa atatatgtag atattaaata
    26521 aatagcttag atagatattt tatgttttaa taagtaattc aattagtggt agatatatac
    26581 tattgaaaat taaagttata attgatataa agaattaata aaaataacat ataaaagttt
    26641 aaaagggagt tgaacttaaa gtttgattag aaaaagtcaa ttttaagaca actcctttta
    26701 ttttactatt gtattaatct gtatctgtaa gtgtattagt ctaatattat aaactttgga
    26761 tgaaattaat tttctatagg ttttaatgta tcatacactt tattttaaag aaacttatct
    26821 taattttcat agtgattgaa tttgtctatt agagatgtta ctattagtaa tgtaaaagca
    26881 agagtagtga atataaaaaa caagatagtg atactgcaag attagaatat aataaatttt
    26941 tatggagaga tttcaatatg gatacatgtt ttaataaaaa aatattactt gttgatgatg
    27001 aaaaggatat agtagattta attgaagaag tactcataaa tgatggtttt aaaaacatta
    27061 ttaaagctta taatggtcta gatgctattt cgctgtgtaa gatagcatgt ccagatgttg
    27121 tcattcttga tataatgtta ccagatatag atggtataga agtgtgtaaa aaaattcgag
    27181 agttttcata ctgttctatt ctttttttat catcaaaaaa tgatgatatt gacaaaatac
    27241 taggtcttag tagtggggga gatgactata taacaaagcc attcagtcca agagaaattg
    27301 cttttcgagt taaagcgcaa ttacgtagac aacagtatca aagcattgta ccatcagata
    27361 gtgaagttat taaaatagga gatattacta ttgatataga aggaaaccgt gtatataaag
    27421 atagaaatga gattgagtta actggaaggg agtatcatct tttaagctac atggctcaaa
    27481 atgtaaataa aattatagga aaagaaagac tctatgaaca agtatgggga gtatatagta
    27541 gtatttgtga caatacaatt atggtgcata tacgacatat aagagaaaaa attgaagata
    27601 acccctcaaa tcctaaaata cttataacag ttaaaggact aggatataaa cttgtgaata
    27661 gaatcgatta gaatagattt taatattaat gaagatatct caagttgaat ttttagttaa
    27721 tgaggcattc ttttatgggt gaaatcaaat gtattttcgt tatctcaaca atgaagaaga
    27781 ggtctatctc tattttgaga tagcctcatt aagtttatat cctggtaatg tactttatgt
    27841 tctaataaaa tttttttagt ttatttgcag tgaaacatta actagaacat taaaatttgc
    27901 attgaaatac caattaaata atattgtata ttgtgtataa acttatacta attgtttttc
    27961 tatattaaat actttatcaa tccaaccttt ataaaatttt tcttcatggg aaactaggat
    28021 tatacttcct ctaaactgtt tcaaagcatt ttgtaaagca tcctttgtct ctgcatcaaa
    28081 gtgattggtt ggttcatcca gaataagaaa attacaagga gataacatca tacaacataa
    28141 tttaacctta gattgttcac caccacttaa agtagataca ctccttgaaa catgctcttc
    28201 cttcacacca catctggcta gatgacgtct aatctctttt gtatttaatt ttggatattt
    28261 atctgctact atttgaagtg gggttttatc aggattttcc cattttaaat cttgctcata
    28321 ataaccaatt ttaacttgtt ctgaaaactg gaaatctcca gatatacgag gaatatcttt
    28381 gactaatgtc tttaacaagg tagatttacc gattccatta aaaccagtta taactatttt
    28441 ttgacctcca tcaacagaga aatttaattt tggaagtaaa gaatagtagt atccaacttc
    28501 aagatttgtt atagtaagag cattttgagc cgatatttca atttctgaaa attgaatatt
    28561 tggttttcct gtaaaactag gaggagctat tctttctatt ttatccaatt gtttttgtct
    28621 tcctcttgca atttttgaat ttactccagc tttattttta cgtataaatg tttcttcttt
    28681 ttctattttc ttttgttgtg cttgatacct tctaatataa tcttctctta aatgtgattt
    28741 ttgtttaagg aactctgaat attttccatg atatttctta atcatgccaa attctatatc
    28801 aagaatacct gtagaaattt tttctaaaaa gtcaaaatcg tgggaaacta caataaatgc
    28861 cccattaaat gtatttaaat aatttgagag ccattcaaca tgctctttat ctaaaaagtt
    28921 tgttggttcg tctaataata gaacatcatg gttagaaagt agtaattttg ctaaaattac
    28981 ctttgccctt tgaccaccac taagctctct aacaacacga ttcattccta ttgaatctaa
    29041 tccaagacca tttgctattt tatttatttc attatctata gaatagaaat tacttgctat
    29101 tagttgttcc tgataatctg atgctttgat tagatattgc tcattttcag atatagcact
    29161 tttttgatag agtaaattca tttccttttc tattttataa agttcttcaa atgcagtgtg
    29221 taaatagagt gatattgttg tatctctatt gatttctgca tattggtcta aatggcctat
    29281 attgatatta ggttgccact tgatttctcc tgaatctgga acaacttctc ccaataaaat
    29341 tttaattaat gtacttttac ctgtaccatt ttggccaact acacctatat gttcaccttt
    29401 gaataaatca aagttagctt tctcatacag tgatttatcc ataaaacatt gtgataaatt
    29461 agttactttt aataaactca taattcaaac tccttttctt ttattaaaaa atttatggaa
    29521 ataaaaaaag cagaggaatg gcattgtaaa atgccgacct ctgcttttgg aaaaacaaaa
    29581 ggtcatagac aagcattgtt gtctatgacc agaaaatcta tattatctat cggcaaatag
    29641 gtaattttaa ataagcatag ccaaaaaact atactaaacc tatatttgcc gatgaagata
    29701 gaaagcttta agctttcaga ttaacctcta cacaacgctt catcgtatac atttgtgtag
    29761 agttaagttt tctaacaagt ttaactaatt ctatataaat cataattatt cacatcctaa
    29821 tcttagtatt aattctagtt tatctgtatt taaattgtac ttttgtactt tgtggattat
    29881 cttatttatt taaaatatgt tttattaatt atagcttaag ttatgttatc ataatactta
    29941 gttatagtca ataagaaagt tatatttact attattatat taatttagta aatctatcat
    30001 tacaaagtta tttgaagact cgctatcaat aaaattttat agtctataag aaaattaaga
    30061 ttatgagttt tataattttg atatagggat actattttca taaatattac aacatgtaga
    30121 agtatatgtc tattattgtt gaattttcaa tgatatatta aggttctaat atattataca
    30181 aaataaaaac attaattcaa cttaaataat tttaagtatt atatgtgttt tgattaaaga
    30241 aaactaaaat tttaaggaaa aataacatat ttgtattaaa ttttattgaa atgattaaat
    30301 ttatttactt aatgtaaatt attagctaaa attgtattaa ataattaagg aggtgagtag
    30361 ctctggatga aatagattta aaaataatta attctctaaa aaagaatagt agggcttcaa
    30421 cctctgaaat aagcagacaa attaatttat cagtaccagc agtctcagag cgtataagga
    30481 aaattgagca gtcaaattta attcaaaagt acactattca aattaatcgg gaaaaaacaa
    30541 aatataagct tttggctttt atatttatca atactgattt atctaaaagt atgaaagaat
    30601 ttaagaaaac tatattggaa tatgatactg tattagaatg tcatcatatt tcaggagagt
    30661 atgattactt aataaaagta ttagcagaag atacaagtaa tcttgaagag tttatatcag
    30721 tgactttgaa ggaaattggg gggattcaaa aagctaatac aaccattgtt ttatctacaa
    30781 ttaaagaaga atttaataca ataaaagata ttttttaaat aatttactag taaagtgtta
    30841 attatatttt aggaggaaaa tagaatatga aagttttagt ttttttagca aaaggttttg
    30901 aaactatgga atttagtgta tttgtagatg ttatgggatg ggctcgtaac gattatgggc
    30961 atgatattga tgtagtgact tgtggattta aaaaacaagt tatgagcaca tttaatatac
    31021 aagtattagt tgataagacg atagaagaag tatgtgttga tgattatgat gctctagcta
    31081 ttcctggagg atttgaagaa tttggatttt atgatgaagc atatgattca tcttttttaa
    31141 atctaataag ggagtttaat tcaaaagaaa aaataatcgc ttctatttgt gtggcagcat
    31201 tgccagttgg aaaaagtggt gttttaaaaa atcgtaaagc tactacatat catttgaaaa
    31261 atggtaaaag acaaagacag ttaagtgagt ttgatgtaaa tgtagttaat gaaccaattg
    31321 ttgtagataa aaatattata acctcatatt gtccagaaac agctccacat gtagctttta
    31381 agcttttaga aatgttgaca tctaaagaac aaatggatga agttaaatta gcaatgggat
    31441 ttaaactgta atggtttata gattttctaa gtaatcagaa ccccagtcac acatggaatc
    31501 taaaattgga ataatactct ttccaaaatc agatagcgag tattctactt ttggaggaac
    31561 aacaggataa accactctta taattaaacc atctgattct aattcacgta attgttgagt
    31621 taacatctta ggcgttgctt taggaattaa tttttttaat tcattgaacc tcaatatagt
    31681 gtctttaaga tgccaaagta taagtgtctt atatttacca ccaatcaatg caagtgttgc
    31741 ttctattggg caactgtaat tatctaaaca ttttttcatt tttgggctcc tttatttatt
    31801 ttaaagtatc tttttaggta ctatattaca aaaaagtgca ttattgtaat atagtaccat
    31861 agtgataaaa ttatagcata ggttaaataa atcatcaact tagcctaata aaacaatagg
    31921 gggtaaataa atgaatttcg ttgaacttgc aaaaaaaaga tattcttgcc gtaattatca
    31981 agatagaaag gttgaaaaag aaaaacttga gaaggtttta gatgttgcaa gaatagctcc
    32041 aactggtggt aatcgtcaac ctcaaagatt gattgttatt caggaaaaag aaggtataaa
    32101 taaactttct aaggctgcca atatatatga tgcgccatta gcaattcttg tatgtggaga
    32161 taaagacaaa gtttggacaa gaccttttga tgggaaacaa cttacagata ttgacacaag
    32221 tatagttaca gaccatatga tgttacaggc aactgaactt ggattggcaa gtgtttgggt
    32281 gtgctatttt aatccagata taattagaga agagtttagt ttgccagata atctagaacc
    32341 aataaatata ttattgatgg gatatgaatc taagatacca gagagcccag agagacatga
    32401 aaaaactcgt gttcctttaa gtgaaattgt ttcttatgaa actctttaat tataaaatta
    32461 agttattcat aggataaatg taataaagtg tttgttataa acaaaattca aaataaataa
    32521 tatctacata taattaattt tagtgaagta tatctagttt aactagaatg tatacttcac
    32581 taatttattt attcaaaata tttatgagga ttttaatata ttaactaaaa tatatcaatt
    32641 gaattaactt ttaaatctgg aaaagcactt gaaatatagt gttttatatc atttaaatgg
    32701 tcttgaattt gcttttctga tattttatca ggtccatata caaaatacat aatattttta
    32761 gtatcttttg ttatagctgt tcgattatca gggccattaa gaatactaga taatatacca
    32821 atattatctg ataaaaataa atcatctttt gttaaaatat gttctttacc acctatacca
    32881 taaaaatgtt cacttccatt tgctaattct attttcaaag gtaattccat tttatcaagg
    32941 tcatgacctg ctgttagaag aagatttttc aattctgcta aaaacattga ctcaattgtt
    33001 acacctacat ctgggatacc ttttgatttt aatagaatag attctaattg aagcaataca
    33061 gggtaagttt tcttgaattt tttataatac tttatataac ttgaaacagg ctctgtttta
    33121 attttttctt tgcgattgta ttctgggtgt tgttctataa tatttttaat tgtagagttt
    33181 ttaagaacta aaaaattttc tttattaggt tttgaatgtg taatatttat aaccataact
    33241 ccaaatttaa tattgggata aatttcttta actttatgtg atacctctaa cataatatag
    33301 actccttttt attttatatt ttatgatata atcttagcaa attaaaagtg gattttatag
    33361 ttccattttt atagtaattt tatagaacca cttttggagg tattagaatg tggattacga
    33421 ttaatagaaa tagtaatata tcattatcaa gacaaattta ttgtgagata aaagatatga
    33481 ttctggatgg aagcttaaag tttgagcaaa aactgccatc atctaggact ttatcaaaag
    33541 aactatctgt atctcgtaat acagttttag atgcatataa tcaattaatt gcagaaggat
    33601 atttggaaac aaggaatgga tatggaacaa ttgtagctaa aggaatatca gggcataaag
    33661 ttgattttaa gttaaatgat acttttagag atgaaaaaga tttacatact aataaacaaa
    33721 aaaattatat agattttcgt tcaggagttc cagaattaaa actatttcca cgcaaagaac
    33781 tttcaaagct atataaacaa atactgtatg atttatcaga ttcggatttc agatatggaa
    33841 gtacagctgg tgtatgggtt ttaagagtgg aaatatctaa gtatttattt cgtactagag
    33901 gaattagatg taatcccaaa aacattatga ttgtttctgg ttcaacacaa ggtttatctt
    33961 taatttcaca gcttttatac aaaagtaata aaaaggttgc tgtagaagac cctattcata
    34021 aaggcttatt aaaggttatt tcatctattg gatattcagt tgttggaatt aaagtagatg
    34081 ataagggaat gaataccaac ttaataaaat caataaaggg gatttctttt gtttatacta
    34141 caccttctca tcaataccca ttaggaggga ttttacctat tcaaagaaga ctagagctta
    34201 ttaaatgtgc aacagagaat gattactata taattgaaga tgattatgat agtgaattta
    34261 gatatgaggg tcaaccaatt agttctcttt atgaacttag cccaaataaa gtaatttaca
    34321 taggttcttt tagtaaaata ttatctccag ctattcgtgt tggatttatg ttattaccag
    34381 acaatatttt agaaagctat aaaaccttaa aaatgtactc tgatgttcat acagaaacaa
    34441 tattgcaaca tgtattagct gaatttattg gaaatggagg tttagagaag tacatattta
    34501 gaatgaagaa gttgtacaat agaaaacgta agtacctcat aaaagtttta aacacggaat
    34561 ttaaaaatga atttaaaata aaaggtgaag cagcagggct tcatatagtt gctcatttct
    34621 ataatgttaa atttacggaa agtttaattc ataaaatttt tgaagcaggt ataaaagttt
    34681 atcctataca acaatatgca attgagaata tattagaata tgactatgaa attatactag
    34741 gttatgctca tcttagtttt gatgaaattg aaaaaggtgt aaaaatactc agcaaaataa
    34801 tacatatgaa tcaaggtaca tagataaaac atgtagcaat ctacatataa tagatgtaat
    34861 taagtttaaa ctttaaaaga aatatatatt aatatttttg tataaaaata cctgatattt
    34921 ttttatcgat actttattgc tatacactaa attaagatag caatttatat taagaaaaaa
    34981 ctttttgcat aggttataat acttaaaagg agaggataga gttgaaaaca aatacagatg
    35041 ttattatgga gataattgat tatatagaag aaaatcttac agaaaatcta aatttagata
    35101 aaatagctta tattgctaat tattcaaaat accatttaca cagaatgttt acaaatgttg
    35161 taggatgtac tatccatcaa tacatacaga ggaggagact tactgaagca gctagacaac
    35221 ttatatttac agacaaatat attatagaca tagctattac agtaggatat tctacacatc
    35281 aatcttttac actagcattt agaaatttat ataaagaatc tccacaagta tatagaaata
    35341 aagatgaatt ttatcctatt caacagagat ttgttttaaa tctaaatcat caaattcaaa
    35401 gtgaaaaatg tatttcttat gcaaatatga attataaaca aagaagagat gaaatcaatt
    35461 cttatcttaa ctttaatatt aattgtgagg tgaaagtagc atgagtttag tgccacatgt
    35521 aattgaacaa acaggtcaag gggaaaggtc ttatgatata tattcaaaat tattaaaaga
    35581 tagaattata tttataggag aagaaattaa tgatgctatt gcaagtttag tagtagctca
    35641 attactgttt ttagaatcag aagacccaga ttcagatata attatatata taaatagccc
    35701 tggtggctct gctacatcag gatttgctat atatgatact atgaattatg tcagatgtga
    35761 tgtatcgact atttgtattg gtatggctgc aagcatgagt gcttttttac ttgcaggagg
    35821 aacacatgga aaaagatgtg ctttacctaa ttcagagatt atgattcatc agccaatggg
    35881 aggagctaaa ggtcaagcaa cagatgtaaa aatagctgta gataatatat tgaaaataaa
    35941 agaacgatta gataaaattc tttctgaaaa tacaggtaaa tcaatagaag atattaggag
    36001 agatacagat agagataatt ttatgactgc actagaggct aaagagtacg ggctgattga
    36061 ttatataatg aataggaatg aataaagtat caaagtatca tattaaaatg tctgttttac
    36121 aaatatatat ataatattaa ataagagtgt ctcaaaatga actttttagt ttatgggaca
    36181 ctcttttttg tatgaaatta aatatggttt tatcatttca acaattatta ccaaatttca
    36241 agtttaataa attctactat aaaaaataca taaaagataa ggttctttag taactttctg
    36301 tcgtcaaaag tttttataaa tttaataaca aaacaagaga aaataccata tattacttat
    36361 gtctgcaata tatagaagac aaaggagttg tacattatga ttacaataag tttgtgcatg
    36421 attgttaaga atgaggaaga agttataggc agatgcttag aatgtgtaaa ggatatagta
    36481 gacgaaatta taattgtaga tacaggttct acagattcca caaaagaaat agtctcaaaa
    36541 tatacagaca tggtgtacga tttcgaatgg atagatgatt tctctgctgc aagaaatttt
    36601 tcattttcta aagcttctaa agactatact atgtggcttg atgcagatga cataatttta
    36661 gaagctgata gagaaaaatt attaaagatt aaagaaagct tggatacttc cattgatatt
    36721 gttatggcaa aatacaatgt atcctttgat gaaaatggta acccaactct ctcgtattat
    36781 agagaacgat tgtttaaaag aagttctaat cataaatggg ttgaccctat tcatgaagta
    36841 gtacctcttt ttggagaggt attttattct gacattgcaa tatctcataa aaagcttcat
    36901 agacaggacc ctctaagaaa tcttagaatt tttgaaaaaa tgatttcaga aggaaaaaca
    36961 ttggagccaa gacaccaatt ctattattct agagagttgt actataatgc taggtataaa
    37021 gaagcaatag aaggttttac taagttttta gactcatcaa gaggatggat tgaggattgt
    37081 atcagtgctt gcagagattt agccacatgt tattacttaa ttaatgatga aaaaagtgcc
    37141 ttatattcat tgtttagaag tttcgaattt gatgagccaa gagcagaaat ttgttgtgac
    37201 ataggaaagc atatgtttga tagacaaaaa tataaagaag ccattttttg gtataaggta
    37261 gcattaacaa gagataagaa tgatactaat ggaggtttta agtcaaatga ttgttatgga
    37321 tatataccat ctatacaatt aagtgtctgt tatgacaggt taggagaatc agataaagct
    37381 atttattatc atgaaaaaac aaaagaaatc aaacctaacg atagtgctgt tttgcacaat
    37441 gaaaattatt ttagtaaatt taaaaatagt tgataggtca caatcatact aaatttgaca
    37501 tattatatat agagcttaaa agctcaaata tatcaggagg tgcttttaat aatgagtaga
    37561 aataaatatt ttggaccatt tgatgataat gattacaaca atggctatga taaatatgat
    37621 gattgtaaca atggtcgtga tgattataat agctgtgatt gccatcattg ctgtccacca
    37681 tcatgtgtag gtccaacagg cccaatgggt ccaagaggta gaaccggccc aacaggtcca
    37741 acgggtccaa caggtccagg agtaggggca acaggcccaa caggaccaac cggtccgact
    37801 ggtccaacag gaaatacagg gaatacagga gcaacaggat taagaggtcc aacaggagca
    37861 acaggggcaa caggcccaac aggagcgaca ggagctatag ggtttggagt aacaggtcca
    37921 acaggcccaa caggagcgac aggagcaaca ggagcagatg gagtaacagg tccaacaggt
    37981 ccaacgggag caacaggagc agatggaata acaggtccaa caggagcaac aggggcaaca
    38041 ggatttggag taacaggtcc aacaggccca acaggagcaa caggagtagg agtaacagga
    38101 gcaacaggat taataggtcc aacaggagcg acaggaacac ctggagcaac aggtccaaca
    38161 ggggcaatag gagcaacagg aataggaata acaggtccaa caggagcaac aggagcaaca
    38221 ggggcagatg gagcaacagg agtaacaggc ccaacaggcc caacaggggc aacaggagca
    38281 gatggagtaa caggcccaac aggagcaaca ggagcaacag gaataggaat aacaggccca
    38341 acaggtccaa caggagcaac aggaataggg ataacagggg caacgggatt aataggtcca
    38401 acaggggcaa caggaacacc tggagcaaca ggtccaacag gagcaacagg cccaacagga
    38461 gtaggagtaa caggagcaac aggagcaaca ggggcaacag gagcagacgg agcaacagga
    38521 gtaacaggtc caacaggagc aacaggggca acaggagcaa atggattagt aggcccaaca
    38581 ggagccacag gagcagcagg aacacctgga gcaacaggtc caacaggagc aacaggccca
    38641 acaggagtag gaataacagg agcaacaggg gcaacaggag cgacaggtcc aacaggagca
    38701 gatggagcaa caggtccaac aggagcaaca ggaaatacag gagcagatgg agtagcaggt
    38761 ccaacaggag caacaggagc aacaggaaat acaggagcag atggagcaac aggtccaaca
    38821 ggagcaacag gggcaacagg agcagatgga gcaacaggtc caacaggagc aacaggagca
    38881 acaggagtgg caggagcaac aggagcaaca ggtccaaca
//
LOCUS       DAGQVA010000032        38900 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.032, whole genome shotgun sequence.
ACCESSION   DAGQVA010000032 DAGQVA010000000
VERSION     DAGQVA010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.032"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            125..607
                     /locus_tag="MIV85_001832"
     CDS             125..607
                     /locus_tag="MIV85_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBY2961173.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIYINEF
                     "
     gene            complement(1306..2460)
                     /gene="nagA"
                     /locus_tag="MIV85_001833"
     CDS             complement(1306..2460)
                     /gene="nagA"
                     /locus_tag="MIV85_001833"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBY2961174.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(2543..3268)
                     /locus_tag="MIV85_001834"
     CDS             complement(2543..3268)
                     /locus_tag="MIV85_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2961175.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            3535..4464
                     /gene="pfkB"
                     /locus_tag="MIV85_001835"
     CDS             3535..4464
                     /gene="pfkB"
                     /locus_tag="MIV85_001835"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBY2961176.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVSK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYYVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(4593..5510)
                     /locus_tag="MIV85_001836"
     CDS             complement(4593..5510)
                     /locus_tag="MIV85_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBY2961177.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMQFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECIKAQRLLEKIINSVK"
     gene            5980..7149
                     /locus_tag="MIV85_001837"
     CDS             5980..7149
                     /locus_tag="MIV85_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBY2961178.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIVEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            7198..8049
                     /gene="gatY"
                     /locus_tag="MIV85_001838"
     CDS             7198..8049
                     /gene="gatY"
                     /locus_tag="MIV85_001838"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBY2961179.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            8375..10276
                     /locus_tag="MIV85_001839"
     CDS             8375..10276
                     /locus_tag="MIV85_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2961180.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            10279..11322
                     /gene="ypdE"
                     /locus_tag="MIV85_001840"
     CDS             10279..11322
                     /gene="ypdE"
                     /locus_tag="MIV85_001840"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBY2961181.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            11337..11642
                     /locus_tag="MIV85_001841"
     CDS             11337..11642
                     /locus_tag="MIV85_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBY2961182.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            11739..12074
                     /locus_tag="MIV85_001842"
     CDS             11739..12074
                     /locus_tag="MIV85_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2961183.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            12106..13428
                     /locus_tag="MIV85_001843"
     CDS             12106..13428
                     /locus_tag="MIV85_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2961184.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            13438..14508
                     /locus_tag="MIV85_001844"
     CDS             13438..14508
                     /locus_tag="MIV85_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBY2961185.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            14513..15700
                     /locus_tag="MIV85_001845"
     CDS             14513..15700
                     /locus_tag="MIV85_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2961186.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(15897..16769)
                     /locus_tag="MIV85_001846"
     CDS             complement(15897..16769)
                     /locus_tag="MIV85_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBY2961187.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(17163..17354)
                     /locus_tag="MIV85_001847"
     CDS             complement(17163..17354)
                     /locus_tag="MIV85_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961188.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            17574..18620
                     /gene="cobT"
                     /locus_tag="MIV85_001848"
     CDS             17574..18620
                     /gene="cobT"
                     /locus_tag="MIV85_001848"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBY2961189.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            18652..19212
                     /gene="cobU"
                     /locus_tag="MIV85_001849"
     CDS             18652..19212
                     /gene="cobU"
                     /locus_tag="MIV85_001849"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBY2961190.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            19222..19995
                     /gene="cobS"
                     /locus_tag="MIV85_001850"
     CDS             19222..19995
                     /gene="cobS"
                     /locus_tag="MIV85_001850"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBY2961191.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            20015..20629
                     /locus_tag="MIV85_001851"
     CDS             20015..20629
                     /locus_tag="MIV85_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBY2961192.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      20696..20875
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            21005..22504
                     /locus_tag="MIV85_001852"
     CDS             21005..22504
                     /locus_tag="MIV85_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBY2961193.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            22543..23919
                     /locus_tag="MIV85_001853"
     CDS             22543..23919
                     /locus_tag="MIV85_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBY2961194.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            23920..24891
                     /locus_tag="MIV85_001854"
     CDS             23920..24891
                     /locus_tag="MIV85_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBY2961195.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFWEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            24923..25993
                     /locus_tag="MIV85_001855"
     CDS             24923..25993
                     /locus_tag="MIV85_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBY2961196.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEEREYML
                     QELRNIRNIKVYDTDANFILIKIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            25995..26882
                     /locus_tag="MIV85_001856"
     CDS             25995..26882
                     /locus_tag="MIV85_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBY2961197.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            26870..27502
                     /locus_tag="MIV85_001857"
     CDS             26870..27502
                     /locus_tag="MIV85_001857"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBY2961198.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            27511..28737
                     /locus_tag="MIV85_001858"
     CDS             27511..28737
                     /locus_tag="MIV85_001858"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBY2961199.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDDGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            28734..29342
                     /locus_tag="MIV85_001859"
     CDS             28734..29342
                     /locus_tag="MIV85_001859"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBY2961200.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            29332..29907
                     /locus_tag="MIV85_001860"
     CDS             29332..29907
                     /locus_tag="MIV85_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBY2961201.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            29900..30652
                     /locus_tag="MIV85_001861"
     CDS             29900..30652
                     /locus_tag="MIV85_001861"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBY2961202.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            30636..31757
                     /gene="cbiG"
                     /locus_tag="MIV85_001862"
     CDS             30636..31757
                     /gene="cbiG"
                     /locus_tag="MIV85_001862"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBY2961203.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYHVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            31754..32479
                     /gene="cobJ"
                     /locus_tag="MIV85_001863"
     CDS             31754..32479
                     /gene="cobJ"
                     /locus_tag="MIV85_001863"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBY2961204.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            32476..33228
                     /gene="cobK"
                     /locus_tag="MIV85_001864"
     CDS             32476..33228
                     /gene="cobK"
                     /locus_tag="MIV85_001864"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBY2961205.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            33247..34725
                     /locus_tag="MIV85_001865"
     CDS             33247..34725
                     /locus_tag="MIV85_001865"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBY2961206.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            34755..35660
                     /gene="hemC"
                     /locus_tag="MIV85_001866"
     CDS             34755..35660
                     /gene="hemC"
                     /locus_tag="MIV85_001866"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBY2961207.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSAIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            35650..37149
                     /gene="cobA"
                     /locus_tag="MIV85_001867"
     CDS             35650..37149
                     /gene="cobA"
                     /locus_tag="MIV85_001867"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBY2961208.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            37166..38131
                     /gene="hemB"
                     /locus_tag="MIV85_001868"
     CDS             37166..38131
                     /gene="hemB"
                     /locus_tag="MIV85_001868"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBY2961209.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            38284..38862
                     /locus_tag="MIV85_001869"
     CDS             38284..38862
                     /locus_tag="MIV85_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBY2961210.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        15535 a         4092 c         6846 g        12427 t
ORIGIN      
        1 cctattttat ataatttatt cctaaaacat gtgaatgttt tttatgatag tttgaagaaa
       61 ttataaaatc actttataat tgaatattat atataaatta atttaaatat agaaaggaaa
      121 atatatgtac aacaatatca aaaatatttt aaaagaaaat catataacgt ttgaagaata
      181 tgaccatgaa cctattttat catttgaaaa agctaaagaa ataagagaaa aattacaata
      241 tactggagta gaaagtaaaa gtttatttat aaaagatagg tctggaaatt actatatatt
      301 tgtaaccaca gaaggaaaaa aattagatcc aaaaactata aaaaatgttt taggtggaaa
      361 agtatctata tgttcaaaag aagaattaac acaaaaaaca caatgtttgc ctggatgtgt
      421 atctcctttt ggatatgaga aaaatatctc tcttgtaata gatcaagata tatttaacca
      481 tgataaaata atcttttcac cagggatacc agaaaagaca tttattatta cagctagtgg
      541 atttaaaaaa gtaataaaca atataaacaa tacaacttat aaatatatat atattaatga
      601 attttaatca taattgtaaa ttagagaaaa taacattaga aatcatgctt aactatagtg
      661 taaataaatt atattcaaca caaaagattg atgctattat tacaatagtt actgttaagc
      721 tcaaattcaa tgtattatga gttattattt ttaaatttta attacaaaag cagggtagtt
      781 ttaactactc tgctttatat ttaacataaa atatataaaa tcaacaaaat gattttagtc
      841 tatctattag atattcttcg ctctcaatgc ttaaaacttt tagatatata caataagtgc
      901 tttcatttgt aaaaatttct atagtattat cttgtttatt tacacctaca atatctttaa
      961 aattgatatg atttttagta tttttacatt tgaaaatata tctgttatca atcaaaatct
     1021 catcattagt aattgaaata tagggtttat ctcatgcttt attaaaaatt tatatgtttg
     1081 ttcaagataa aaacttacaa ataataatag aaaagttact ttaaatgtac atattatcga
     1141 aaatattatc acaaaaatac ttataatata tatttgttta aaataacctc tatcgcaata
     1201 gtttattaac gatatggaaa taaaagtgtt aaatcagatt ttggagaaat aactttaaat
     1261 atttccagac tctttttaga cagcctccat aaccttatat tgaacctatt tattaacttt
     1321 gtacttacag ataccattta tataagtttc gtgtatatta aagtcattat ctgttactat
     1381 aaagtctgca tccatacctt gatatataga gccacagaca ttatcaatat tacaacttaa
     1441 agcagggaca tatgtagcca tttttattgc atcttctaaa gttgatatgt tccaatcaac
     1501 tatatttctc acagccttgt ccatagttaa tacacttcca gctaaactcc cactatttaa
     1561 tcttgcaaca ctatttttta catttacatt aaacttacca agagtatatt ttccatcctc
     1621 catagcacca gctctcatac aatctgtaat taaagctatg ttattactag acttagcatc
     1681 catcattatt ttaacagcta ttgggcttac atgatgacca tcacaaatta attcagcata
     1741 agtatctttt agtaccatag cagccccaac cattccaggt tctctatgat ttaaaggact
     1801 catcccatta tatgtatgta caaacacttt agcacctgaa ttaacgactt gtttaacttg
     1861 ctcaaatgta gctgaactat gaccaagaga aactgatata ttatttttag ttgcatatct
     1921 tgttaattct attgaacctt tacgttctgg agcaattgct atttttctta ttaaattttt
     1981 cgattttttt tgccataatt ttaatatatt gatgtcaggg tctttaaaat atttttcatt
     2041 ttgagcgccc ttatattttt ctgtaaaaaa tggaccttct aaataaatcc cttgtatttt
     2101 tgcaccctca actcgattga agctattgct tatattttct acagaatcac ttagtgtatc
     2161 tacagaatca gttaaagttg taggtaggaa agatgttact ccatatttta ataagccttt
     2221 tgaaattgtg tttattgctt caaatgtatt gtccatgaca tctgcaccta aaagaccgtg
     2281 aatgtgagta tcaactaagc caggagcaat atatttacct gaaaaatcta taacattatc
     2341 agtaacatta ggtctttctt gttgaaattc accgaatttg ccattaatta tactaaggta
     2401 acctttttct ttgattccat gtttcataaa aaatttatct gcataaataa aacttttcaa
     2461 aataacctcc ttataattat attatcattg tggcattgac gcttataata tcattctgtt
     2521 ttcttgaaag ttatttaact tactatctta catgtcttac tctatataca aatttatcac
     2581 ttctagcgac actcaaagta aattcaataa ctatattgtc atcattatat gtggtacgaa
     2641 gtaatttcag acaaggtgaa tctcctggta cttccaataa cttagcttcc ttatccgaga
     2701 ttattccagc tgaaaattct tcatcagcaa ctttaataat ctcgccataa tcttctctaa
     2761 atatttcata taaaggtttt tgttcgattt tttcttttgt caatcctata aattctttca
     2821 taggaagata tgttctttca agcatcatag gaaggtcatc agcaagtctt aaacgcatta
     2881 tttttatcat tttttcacca ggagttatac ctaatttttc agagaaatac tttgtacttt
     2941 ctactacctc aaatgataat acctttgtac ctggcttttt tccttgtgtt ctcatataat
     3001 ctgtaaaact ataactttcc attaagtttt gagaattttg acttagtgca gcaacaaaag
     3061 ttccttttcc atgtcttttg tatatatatc ccatatgctc taactcagcc atagctagtc
     3121 taactgtggt tctacttact ccatattcat cacaaatttt tctttcggaa agcattctat
     3181 cgtttggttc catctcattt tcaatcttag ttcttaatat ctcaacaagc tggtcatata
     3241 ttggtctttt atcatttctt tttatcataa aaatatagtc ctttctaagt ggttattacc
     3301 acaatttgat tatagaatat agaattattt atgtcaatga ataaagttta atcaaaattc
     3361 aataagtaag gctattaatt tattataaaa ttatggtaca ttgacaaaac aagtaaaata
     3421 atttatattc aaattggtaa taaccacttt ggatatatta tatgaggtat tttttatttt
     3481 acagattaat ttattgttta gaaaagtaaa aattaataat gaggagaatc tagtatgatt
     3541 acagtaataa cattcaaccc atctatagat agaatgtata gagtgaataa tataaacata
     3601 ggtgaggtgc aaagggtagt aagtaagaat gcaactgctg gaggtaaagg attaaacgta
     3661 tctaaggtat gtaaaatttt aaaagaaaat cctttagcta tgggatttct aggcggattt
     3721 aatggagaat ttataaaaaa tgaacttaga aaactagata tacaaaataa atttacaaaa
     3781 atagagcagg aaactagaaa ttgcttaaac ataattgagg acaataaagt tagtacagaa
     3841 tttttagaaa aaggaccaat agtagaaaaa agcgatttag agagatttga aaatgatata
     3901 gaggaagtac taaaaaatac taaaatactg gtagcttctg gtagttattg tgagaatatg
     3961 ccgatagact attatgaaaa gataggaaat atatgtagag caaataatat aaagtttata
     4021 ttagatacat caggagaagc attaaaaata gctttaaaat caaaaccata tttaataaag
     4081 ccaaatatag atgaaataag acatttatta ggaataaata tagaatcaag agaggaaatt
     4141 atcttgtcag gaaaaaaact tattgaaatg ggtgcagaga atgtatgtat atctttagga
     4201 aaagatggta tggtgtattt aaacgaagat aacgtatatt atgtaaaagt accagttgta
     4261 aagtgtataa atactgtagg tagtggagat agcacagtgg ctggatttag tgtaggtatt
     4321 ttaaggggtt ataaaataga aaatttactt aaatttgcaa atgcttgtgg tataagtaat
     4381 gctttaaata tggaaactgg atttgtagat ttgggagaaa ttgataaata tcaagattta
     4441 gttgaagtaa aaaagttaag ttaaatacat ttaatgggaa tataataaat ttaatgttgt
     4501 tgtaatagat tttaatttta atataaaaga tatagtctta tataaaaata ggttagaaaa
     4561 attcattttt aacctatttt tataataaat atctatttta ctgaatttat aattttctct
     4621 agtaatcttt gagccttgat acactcttct ccactgatag ctggttttat attattttct
     4681 atacaatcaa taaaatgatt tgatatatcc tcaaaaccct tttgttttaa tatatttacc
     4741 catgcaccac tttgctttaa agttaggttt ccaccttctt ctatttccag tacattaaga
     4801 ttcttaactc tttgaatctt accctttgaa agaatttcaa cttgttctaa ctttgttcca
     4861 gaatctctat gcatagaggt gtttatagag aaatttttac ctttaagttt atgacttaca
     4921 aatataagat tcttattgtc tgttaaaaat aaatcctctc cactaatttc aacatcttca
     4981 tttgctaacc ataaagcagt gtcaataaca tgtatatagt catctataag agtactgtcg
     5041 aatttaacat ttcttaagga atttaatcca tgtttacata tattgataga tacaatttct
     5101 gtagcattat ttttaatttc tttgtacata ggacagaatc tacggttgaa tccaaccatt
     5161 aaatttaagt tttttttcgt acttaattcg ataagttctt ctccttgact tactgttgaa
     5221 gcaagaggtt tgtctacata tacatgaaca cctaaattta ataatatttt tataatttcg
     5281 tagtgtgttt ctgtagagct atgtagaaaa atacaatcac attttttagc tagggattca
     5341 atagaatcga attgcatgat tctataatca ctacagactt tttccctttt aactttattt
     5401 ggagtaaaag ctcctacaaa ctcaaatctc tcagacttag ttaatatagg taaatatgcc
     5461 ttttgagcta tggagccaag acctatcatt cccattttta tatttttcat aatactttct
     5521 cctaaggttt ttatatttac agaattgatt ataattcaga cacataaatt tgtaaacttt
     5581 gtatcaaaaa ataaatttaa agcttatata agtaaattag cgaaataaga aatattgata
     5641 aagtaatttt gtaggatatc tataaaattg attgatataa atattttatg tattgacaaa
     5701 aaattcaaat taatttatat ttggattagt ggtaattacc actttggtct gaacaagttt
     5761 ttatcgtaaa ataaaaatac taaagtatat agagtatgat tttattaaat ttttaaagat
     5821 aaactataaa attaattaaa atctatagtg tatattttat agtgagttta agtagtacta
     5881 aaaatctaag caaaaaatta taaaagagta tattttttta tagtttaaag tggttataac
     5941 ctcattacca aatgtaaacg ttacaagtat gaaaggagaa tgaaaatgtt taaattagaa
     6001 gaacaaaaac taaaagattt aggtgcaata ataacaacta atgaaataaa acaacagcct
     6061 gaattatggt tagagactta tgaaatatat aaatctaaca aagaaaaatt aagtagattc
     6121 atagatacaa taagtaataa tcatgggcag tttagagtta tatttacagg tgctggaact
     6181 tcagcttaca taggaaattc aatacttcct taccttaaaa ataaaaatga cataagaaaa
     6241 tacatatttg aagcaatacc tactacggat atagtttcaa acccatatga ttacttaaaa
     6301 aaagatatac caacattatt aatttcattt gcaagaagtg gaaatagtcc tgaaagtttg
     6361 gctgctttaa atttagggaa taagattgta gataattttt atcatttagc tataacttgt
     6421 aatccagaag gagaactagc taagatgact aaaaacgacg aaaataatta cttgttatta
     6481 atgccatcaa aatcaaatga tgaaggcttt gccatgacag gaagtttttc gtgtatgatg
     6541 ttatctgcta tgttaatatt cgatagttta gaagatgatg tagaaaagtc atatataaat
     6601 gcaatagttg aaatgggaag aaatgttata gatagaaaag atgaaataca tgagttaata
     6661 aataaagatt ttgatagagt tgtatattta ggttcaggag gattaggtgg tttgacacaa
     6721 gaagcacaac taaaactttt agaacttaca gcaggaaaaa tatctacagt gtatgattct
     6781 cctatggggt ttagacacgg accaaaatca tttattgatg aaaatacact tgtatttgaa
     6841 tttgtatcta actgtttata tacaagaaaa tatgatttag atgttttaga ggagataaaa
     6901 agggataaaa ttgctaaatt cacttgtgca gtgtcagtag aaaatgaaaa taacttctca
     6961 ggaacaaagt ttgagtttaa agaaaagtat aataaattac cagatgtgta tcttgcaatg
     7021 ccatacatat tgtttgcaca aactatagca ttgtttgtat cggtaaaggt tggaaataag
     7081 ccagatacgc catcagctac aggaacagta aatcgagtag taaaaggtgt aacaatatat
     7141 gaatattaaa agataagatt aaaatattat aactaaataa tttgggaggg tatcaatgtg
     7201 gcattagtaa caacaacatc aatgcttaaa aaggcacaag atgaagggta tgcagtagga
     7261 gcatttaatg tagaaaatat ggaaatggta attgctgtta tagaagctgc tgaggagtta
     7321 aattctccag taatattaca aactactcca tctactgtaa aatatgcagg tcttgattat
     7381 tatctagcaa atgcaaaggt tgctgcagaa agagtaaaga tacctgtagc aatgcatctg
     7441 gaccatggtt caagttttga ccttgcaatg aaagctttaa gaagtggata tacatcaata
     7501 atgatagatg gttctcatga aagctttgaa aataatatat ctatatctaa atcagtagta
     7561 aaagcatgta gtccttctct tataccagtg gaagcagaac ttgggaaagt tggtggaaaa
     7621 gaagatgatt tagatggcgg gaatagtaat gattatacaa atccaaaaga ggcaaaagag
     7681 tttgtcgata gaacaggaat atcttcattg gctattgcta taggtactgc acatggattg
     7741 tataagggtg aacctaaaat agatttagat aggttatcag aaattaaaaa tgtagtttca
     7801 atacctttag tattgcatgg aggttcagga atacatgatg atattataaa agaagctata
     7861 aaaagaggta ttgcaaaagt taactatgca actgaattaa gaattgcata tagtaaaggg
     7921 gttaaaaaag ttttagatga agattctgag gttatagacc ctaaaaagta tggattagca
     7981 gggcttcaat cagtaaagga ttttgtgaaa gaaaagatta aagtgtgtgg gtctgtaaat
     8041 agagtataaa aataaaatat cctaaattta ttttagataa gtttaggata tttgttatat
     8101 gaaaaattta tattaattat atgtaaatgg tgtatttttt tcatttaatt gatgaaaaat
     8161 atcagctttt attggtaaag tattacatat ataattaaaa tatactaaaa attgaactat
     8221 atattttatt attataaaat atttatatta aattgtggaa ttaaaatata ctaggatata
     8281 aaattcttaa ataaaaagaa aagattgttt ttataaaaaa tattttttat accacttaaa
     8341 aaaacacaat aataacactg agggaggtgg ggatatgaga gaacgcatta ttcttgaaac
     8401 attaaaaaat agtagtggtt atctaaacat agattatttt gcagataagt tgggggtatc
     8461 tactcgaact atcagaaatg aaataaaaaa gatagaaact ataaaagaat gtaatggttt
     8521 taaattagaa tataagtcta aattaggata tattctaaat attaaagacc aagataaatt
     8581 cgagcattat ctaagaaact taccctcaga tttagttgaa aatccagaac aacggttaga
     8641 gtctataata gtagaacttt tagtaaatga aggttataaa actatagaac agttaagtaa
     8701 aaaatttcta gtaagttcat cccaaataaa aaatgattta aaaaagatag atgaaaagat
     8761 aaaggataca gaattaaaac tagagcgaaa ggctcattat ggaattaaaa tagaaggttc
     8821 tataaaagaa attcaaagta tattggtgga tagttatttt agagggaata gaaatataac
     8881 agagtacagg aataagttta tagataattt aaaattagct aatattagaa gtacaataaa
     8941 aaatgtactt aatgaacatg atttagaagc aaatttaaca gaacttgagg aaatattagc
     9001 acaaattatt atattgtata taagagttag tatgagagta gcgggaaatg ctagcgattt
     9061 aaaattatat acagaagatt taattataga taaattatta gataaaattt ttagagataa
     9121 aaaatataac cttaattatg atgaaaagta ttatttaaag gagcttataa aactaaagac
     9181 taaagataag aaagccacta taaagaatat tgataagaat aaacttcaag atattatgtt
     9241 cgaatttttt agagagatag ataaaaaata taactctaat tttttagaag ataaagagtt
     9301 ctttaactta ttttacttac atattgcatg tttaatagaa cgtataaaga agaaccacaa
     9361 gataataaat cctttttcag ttaaaataag tcaacagtat ccaactgttt ttaatttatc
     9421 tattcaattt tcaaaaatca tagaaaatga gtatcatata aaaataagtc aagatgaaat
     9481 agggtttata gctactcaca ttgctgttcc ttttgaaaag agagaagaag ctaattttaa
     9541 taaaaaatat aaaatagcaa taatatgctc ttctggtgga ggtagtgcat ttttgataaa
     9601 tttaagactt aaagaaattt ttccaaatgc tgagataaga aatttttcat tactagaaga
     9661 aaaagctgta atagaatttg caccagattt gattttttca ataacaaatc ttttatttga
     9721 aataaatgct ccagttatac ttataaatga aattttagac gaattggatt atttagatat
     9781 taaagaaagt gttagatttg cagaccatat aggaaatata tcaagcccaa aacaatatat
     9841 attaggtcta tttgataaga atcactttag gtgtataaaa gataaagcta agtataagga
     9901 tatccttgat agtatgtcaa aatgtatagt tgacgagggc gcttgttctc caacctatcc
     9961 caaagatgta tgggaaagag aaagctattt gagtactatt tatacaaatg gggtggctat
    10021 acctcatcca atcgagatga caggaaacaa aaatataata tcagtagctt tgatacaaac
    10081 tgatattatt tatgaaaata gggtgcctaa aattattttc atgatttcat taataaaggg
    10141 aaatttagaa cttcataagc aaatatctaa atatttaagt aagattatgg caaataagga
    10201 tatggtagac atgctaaata agtcacaatc ttatgaagag tttatgtata agttaaaaat
    10261 ctatctggga ggttagacat gaatatagag ttttttaaga ggttgtcaga agcagatggt
    10321 atagcatcta atgaagaaga ggttagacat gttttattgg aagaactaaa agcttatagt
    10381 gataaaatta tctgtgatgg gctagggagt atcatctttt ctaaaataaa agatgagagt
    10441 gcaccaaacg taatgatttg tgctcatatg gatgaagttg gatttatggt gagaagtata
    10501 gacaaacttg gtatgattca cttaataaca ataggaggag taaaacctct tgcacagttt
    10561 gtacaaaaag ttagaattac aacaaaagaa gggaagaaaa tccctgctgt cataaatgct
    10621 acatataata atggtaaggc tgaaaatata tatgcagata ttggagcata tacagaagaa
    10681 gatgtatata acctagggat taatgttggg gatatggtaa catatacaac aagctttgag
    10741 gaatttactt taccagaccg attagtggga aaggcttttg atgataggat aggatgtttt
    10801 gtgatgggag aagttttaaa agaacttagg aaagaaaatc taaattgtaa tattcacttt
    10861 gcggctacaa gtagtgaaga ggttggaata aggggagcaa agacatcaac acagttaata
    10921 aatccagata tagtatttgt aatagatgta gcatgtgcta aaaatgagtt tgtgagagac
    10981 tatacaaatc agaaacaaat tgataaaggt gtaatgctaa tgcatagaga taggactcta
    11041 gtccctagta gaaaaatgat agattatgta atggaaattg ctgataaaaa taatatacca
    11101 cttcaacatg atatgtttga atcaggtggg actgatggag gagaagcaca tctcgtaaat
    11161 gaagggaaac cttgtgtagt aacttgtgta ccagttagat atggtcattg tgcattttca
    11221 atagtaagta ataaagattt agagaacatt ataagattgt atacacagtt aattttaaat
    11281 tttgatgaag aacaatataa acatataaga aattttatct aaaggagaat aagaaaatgt
    11341 caacagaagt acaaataatg gaacttatat caactgcagg agagagtaaa tcgaaagctt
    11401 ttgaggcttt aaaaaaagtg aagtcaaaag attttaaagg agcaaaattg ttaatagagg
    11461 aggctcgtaa aatagatatt gaagctcaca ggatacaaac agaattaata actcaagatt
    11521 taaatgaaga tgttgaaagt ccagcaatga gtcttttaat ggtacatgct caagaccact
    11581 atatgacttc tcagctagca aaagacttga tagaggcttt gatatattgt cttgataagt
    11641 aattgtaata tagaaataga ttatttatgt aaaaattctt ttaaaagttt agatgctttt
    11701 aagagataat aaaaatacaa actttaggag gaattattat gaaaatatta ttatgttgtg
    11761 caggtggatt ttctactaat atgttaatgc aaaatatgaa aaaggtggta aaagagagtg
    11821 ctaaactcaa tgaaaaagat tttgagttta cagctatacc agcagattca atagaaagtg
    11881 aagttgatga ttgggatata gtacttatag gtcctcaaat agctcacaaa atagacttct
    11941 taaaaggaat attagagcca aaaaataagc cttttgcagt aatagataaa gatgtatatg
    12001 gaaaaatgga tggagctaca gttatgaagt tggcattaat aacttataag aaacatcaat
    12061 tagctcaagg ataataaaaa taatgaggga aaagggagat tagatatgtt ttcaaaattt
    12121 gaagcattta tgaatagagt atttatgcct ttagctcata aggttgacaa tcaacgtcac
    12181 cttggttcta taaaggctgg tatggttgct atgacaccat tcacaatatt aggaagtata
    12241 tttgcaatac ttccagcact tccaaatatg cttggagaaa ataatccaat aagcaaattc
    12301 atacttaaca attcagcaat attggattta ccagtaagtc tttccatagg tttaatagga
    12361 ttatatgctt gtatgtgtat tgcttttaat ctggggaact actataaatt atatatacca
    12421 ggttgtgttg cactatcaac tttttctttt ttattcctag tagcatcatt tacaccagat
    12481 ggagctttag aaataggaaa tttaggagct aaagggctat ttacaggtat gatagcaggg
    12541 cttggttctg tggagttata taatttttgt aataagaaga atatcacaat aaaaatgcca
    12601 gaaaatgtac ctgattttgt atctaggtct tttgaattaa tacctactac tataatagtt
    12661 tgtggaactt ttatagttgc tcgttttatt tcattaaaag tatttggaga attacctcca
    12721 cagatactta ctcaattttt atctccatta gtaggaagta tggataaccc atggtcagtt
    12781 cttgcactta actttgctat atgtactata ttcttttttg gaatacattc atcagtattt
    12841 agtcctataa ctagacctat aatgattaca tttatagctg aaaacatagc agctatgcaa
    12901 gctggagaaa caatacctca tttctttaca gcaggagctt caagtgcatt ctttggattt
    12961 acaggatgtg gaattagtat aggttgtgta attgcatgta tgttatcaaa aaatgcttcc
    13021 tataagaaga ttggacgtgt atcattattc cctgcattat ttgggataaa tgaaccaata
    13081 ttatttggag caccgataat attaaatcca ataatgttta taccacatgt atttggtgga
    13141 gctataatag gtacactacc aatgtttttt atgcactggg gatggttagc aaagccagta
    13201 tttgaccctc catatgtagg ggtattctta gaaggatttt taactaatgg agattggcat
    13261 tctatattag caaatgcatt gcaattagta ttagcagttt tattatattg gccattcttt
    13321 aaaataatgg aacgtcaaca aaataataaa aaacaaaaag aagaaactaa gaatatattc
    13381 tctaaagaag aagaagactt attggatgat ttaggattgg atttctaata ttttgttatg
    13441 aataatacaa tggagagatt agtatcctta atctataaaa gaggtgttga cgctcttttg
    13501 attaaagcaa aaaatactaa aagatatata ggagctttat caggtagtgg tgtatatgtg
    13561 cttgttacta aggataaaaa ttatcaaatt ctagatggca gatatattga tgaagcagat
    13621 aaaaaaacga ctggtttcat aaaaaggatt gtatctcaag gttcttatat accaactata
    13681 attgagttat taaaagaatt aaatataaaa aagttagcaa tagaaaacca agctatgagt
    13741 atacaagagt atctttcact aaaaaatgaa ggttttgaaa tcaatttaat aacaaatgaa
    13801 ttatggaagc taagggctat aaaatctaaa gaagaaattg aacttattaa aaaggcttgt
    13861 gaaattacag atgaagtatt tgatgaggtt atttctgaaa ttaaaaaaga tatgactgag
    13921 ctagaagtat cagctctaat tcagtatcat gcattaaaaa aaggtgcaag tggaatgtct
    13981 tttgaaacaa tagtggtatc aggagaaaga ggtgcaatgc cacatggaag acctacaaac
    14041 aaaaaattga aagtgaatga agctataaca atagattttg gtgttgttta tcaagggtat
    14101 caatcagaca tgactcgtac aatatctata ggtaaacctc ctaaaattat taaagagata
    14161 tatgatgtag tattggaagc acaattatct gcaatagagt caataaagga aggaactagg
    14221 gcaagtgatg ttgacaaagt ggctagaaaa attatagata aacatggatt tggcgaatat
    14281 tttaatcatg gactgggtca tggtataggt cttggagatg gtgaagtccc cactttaaat
    14341 ccaaatagtg aagatatatt agtggaagga atggtaatgt cttgtgagcc aggtatttat
    14401 attccaaatg tagggggagt tagaatagaa gatgacattg ttataataga tggaaaaggt
    14461 gttccactca ataagacatc caaagagttt ataatattag gagagtaaaa ttatgaaata
    14521 taattttaat aaagtattaa atcgtaaaga aggaaattgt agaaaatgga gcaaccatgt
    14581 gattaaagaa aaattcggct taaatgaaga tgcaattcct atggatttag ctgatatcga
    14641 ttttgagtgt gctcctgcta taaaagaatc tatcttaaaa agagcatcag taggagatta
    14701 tagttatact tttataggag atgacttcta tgatgcgatt ataaattgga ataaaagaag
    14761 atttgatgta tatatagaaa aggattggat aaaattaact tttggtactg tttcaaccct
    14821 tcattatata gtccaagcat atactaaaga aggagagggt gtattgataa atacacctgc
    14881 ttatgaccct tttgcagagg ctgtagtaaa taataataga aagttgtgtt gtagctcatt
    14941 aaaattagat aacaatagat attatttaga tttagaggat atggaaaatc aaatgaaata
    15001 cgagaatata agattgctta tattctgtag tccacaaaat ccatcaggtc gtatatggac
    15061 aaaagaagaa ctatatcaag tgtcagagtt atgtttaaag tataatgtaa ttttggtaag
    15121 tgatgaaatt catagagata taatatttaa agattataga tttgtatctt tatggaatgc
    15181 tcatccagaa atttataaaa atagtataat ctgtgtatct cctaataaag gcttcaactt
    15241 aggtggatta aaaacatcat atgtattaat aagagatgta aaaattaggg agactttatt
    15301 agaaagacta aaaagtaatt caataacttc tccaaatgta tttgcaatac cagcaatagt
    15361 tgcagcatat aatgaaagcg aagaatggct agatgctatg actagttatg tagaggagaa
    15421 ttttgaaata gtttatgatt tctttgaaac taatatacca aaagctaaag tgatgaagtc
    15481 agactcttct tttttagcct ggatagatgt aagagaagta tttagaaatg aagaagaatc
    15541 taaagaattt tttagacatg caaacttaac tatggtagtt ggaagttatt ttgtgaaaga
    15601 tggagatgga tttattcgta ttaatgtggg gtgtcctaga gaaacattaa atgaggctct
    15661 aaatagaatc aaaaaaacgt atataagtat gtattgttaa atcataaaaa aagtatctat
    15721 ggtttatata aaaacacatt atttagttat caaatattac tggaattttg tattccagta
    15781 atattttttg attaaggaat attattgagg aatattaaat aatattattt cataccctta
    15841 tattaactta tataaaaata ttttattatt ttgggaacgg gttagctaac ctttatctag
    15901 tgtatattta tattgtaaga agcagtaaaa acttttcctt tactaagttt attaataaac
    15961 ttcttatctt tataaatttt gttagaattt atactatcag caagaccata ccaaggttct
    16021 atacataaaa aaggagcagt agaattagtt tcactataat aaggagtcca aataccaact
    16081 agagggaaat cttccataga tatagttaca tatttactac catcattatt acatatagat
    16141 acttcatcta tgttggtgta tatcaaagca tcattcttga atacttctgg atttaactgt
    16201 aagtttttta attttccaat aggtattata tcatctgtaa aagaaccatt taaattgatt
    16261 ttttctacat catttttact tttaaactca aggtagtgtt tagaaaaatc attttgttcg
    16321 taaaaaggaa ggttgaatgc aggatgtcca cctatagaaa agaatatatc tttagaatca
    16381 gtatttttta caatccattc tacctcaata ctattatcat ttaatgtata gtttatgatt
    16441 agctcaaaag aatatggata cttctttaaa gtagattcat tatctgttaa tttataagtt
    16501 acaaatgtat ctcctttatc tacaatctca aagtccatat ctctagcaaa cccatgttga
    16561 gtcatgctat ataaattttc ttctattatt gtttcattat caaaaagttt acctactata
    16621 gggaacaata taggtgattg tctaccccaa tattttttat taccatccca aagaatgttt
    16681 ttgtcgtatt ttttagaaaa tattttagtt agttcagcac caaaactgct tgattcgata
    16741 attaaatttt cattttgtaa tatattcatt taaaatctcc tttattatat tttatgagta
    16801 tattatacta taaagtataa agattattaa attttatttg atattatatt tgaaaggtag
    16861 attttagtat attttgaaaa ttttgttttg aaaatttggg attatttaag aaattttgta
    16921 ttataaatag aaggaaatag ataaattgta tagaataaaa tatattaaga taagttaata
    16981 atgttaaatg ggaagtgagt ttatggaaaa accaaataca aaagttgtta actttcaaga
    17041 gtataaagac agaaaaaacc aaagagaagt aaatagagac gaacttttaa agcttataaa
    17101 aaaaattgtg acttcaaaat agggagttgt taaactccct attttaatgg gtttcataat
    17161 aattaagaca ttctgagtcc atctatataa tctttgaatt gtgagaaatc tgattcacta
    17221 cttaattcta tggtttctga accttccgta taaaaattct taagatagat agtataatta
    17281 ttatcaacac aatcatgata aatacatcta tatccatctt catacaaact ttttaactta
    17341 gaaaaatcat ccacaatatc atctccttaa agttctttta aatatatttt tacaaaaagc
    17401 atctaattgt atgcaaattg acaatgtaaa ataaaggaaa tgaacataaa atgtagaata
    17461 atttttatat gtatgtaaaa ataaaaagaa aaagttgaaa tttttagaaa ataagagtat
    17521 tttttatcta aaaagagagt ttaaaaaata aaaaaatgtt gggaggataa aaaatgagtt
    17581 tattagaaag tatatcaaaa aacatatatt ccctagataa ctcttctatt gaaaaaacaa
    17641 agcagagatt ggataggctt atacatccaa ctggaagctt aggaaagata gaagatattt
    17701 gcatgcaatt agcaggaata tttggcaatg aaaattttga cacaagtaaa aaggttataa
    17761 ttgcttttgc gggagaccat ggtgtatatg aagaaggcgt agcacctgac cctcaaaata
    17821 taacaaaatt acagtttcca aatttttcga aaggtctatg tggagttgga gtaataagta
    17881 aatttgtagg ggcagatgtt gtagctgtag atgtaggaat aaactgtgat gaaaaactgg
    17941 atggggtatt agactacaag ataagaaaag ggacatcaaa tatggcaaaa ggtccagcta
    18001 tgagtaaaca agaagcaatt agatgtttag agataggtat tgaaatagca gagcagtgta
    18061 tagaaaaaga ttataaggtt attggtattg gggagatggg tatagcaaat actactccaa
    18121 gtacagcaat aatatctgta atttcagggt gtgacccgtt agaagttact ggtataggtg
    18181 caggtcttaa gaaagaaaga ctaaagcata aggctgaagt aattagaaag gctattgaaa
    18241 ttaataatcc aaatccaact gatggagtag atattttatc taaagtagga gggtttgaaa
    18301 taggctcaat ggcaggtgtt atattaggtt gtagtgctaa taggattcca gtagtaattg
    18361 atgggtttat ttcttatgca gcagcattaa ttgcatataa gataaatcca aaaactagag
    18421 aatatatgat agcatctcat ttatcagcag aatcaggaac taaaagagca ttagacatat
    18481 taaaattaga ccctctatta aatatggata tgagattagg tgagggaagt ggagctgctt
    18541 tagcatttga tataatagaa gcttcaaact atacttataa aaatatggca acttttgatg
    18601 aaattgacat gggaagataa atataaaaat ttaatatgta ggagtgtttt gatgagtaaa
    18661 attattctag taacaggagg agctaggtca gggaagagta actttgcaga aaaactatgt
    18721 tttgacagaa ataataatac agcttatata gcaacctcta ttccatttga tgatgaaatg
    18781 aaagatagag taaaaaaaca tcaagagaat agacctagaa actggaatac ttatgaaata
    18841 tatgaagata tatattccat aattaaggag atatataaag aacatgaaac tgttatacta
    18901 gattgtgtaa cattattagt aaataatcta atgtttgaac acaatctaaa tatagaagaa
    18961 tctagtcaag aagaaataaa caaattagaa caatacataa aagaacaagt tgtcaaactt
    19021 attgaagaaa tagaaaaaac aaatctatac tttgtatttg taacgaatga gttaggtatg
    19081 ggaattgttc ctgggaataa acttagtaga atttatgctg atattgtagg tcgtataaat
    19141 caatatatag cttcgaaaag taatgaagtt tattttgtag ttagtggcat agctatgaag
    19201 ataaaggagt agtatgcaat tatgaaaaga tttattttaa tactacagtt tttgacaagg
    19261 atacctataa aattaaatgt aggatttgat gatgaatttt ataagtcaat agtatatttt
    19321 ccacttgtag gttttgtcat aggtatatta tcctatttaa taggatggat ttctatgctt
    19381 ttatttgaac catttatagc ttctataata ataactctag ctggtgtctt aattactgga
    19441 ggacttcata tagatggatt aggagataca tttgatgcaa tatatagtta tagggataaa
    19501 gaaaagatgc ttgaaataat gaaagattca agattaggta caaattcact tctagcaatt
    19561 atgtttgtac ttttattaaa ggttggattc gtttacgata taataagtaa taattcattg
    19621 tgggttataa tttttatgcc aatgattgca aggttaggag taatgttatt gacatataaa
    19681 actgtgacac caagagaaaa aggaatggga aatttattta taggaaaatt aactacaagt
    19741 atgttaataa ctgctataat atacacatta ttgatagttg ctcttattac taaatttata
    19801 tttttattac ctaatatagt gttgattaaa gtattaggtt cgattatagt ggtttttgta
    19861 tttataatat tattcaaaaa acatatttat aaaaaaattg acggagtaac aggagatata
    19921 ttaggctgtg gaatagaact ttcagagctt gtatatttaa tttacatata tttgttaatt
    19981 tttatgtttt tttaaagtaa aaagtggtga taatatgata agattaatat taataagaca
    20041 tgcactgaca aatgataata aaaaaggaag attatcaggc catataaata gttgtattag
    20101 tgaagagggc aaactacaaa taaataaaat taccagatat ctgagtaatg aaaacataga
    20161 taaggtttat acaacaccat ctacacgtac taaagataca gtagaaaaaa tatcaaaatt
    20221 gaaattatta gaaatagaag aaaaagaagc tttaagagaa attagttttg gagactttga
    20281 aggaagaact tttgaagaaa ttaaaatcaa atatccaaat gagtttgaaa aaatgataaa
    20341 agaaggtaac aactatagat atccaaatgg agaaagtttg atagactctt ataaaagagt
    20401 ggcaaaagaa attgataata taattttaga aaatgatagt aatttagata caaagacaat
    20461 acttatatgt tctcatgcag gaacaataag aaatataata acacatttga tttctggtag
    20521 ttataagtat cactggaact ttaaaattga taatgcatct attacagttt tagaaattga
    20581 tggtggattt gctgtaatag ataaaatgaa ttttacagac ttcatataat ttaatcaaaa
    20641 ccaaacatta caatctgtgt ttgtaatata tctgtaaaat tagcaatgaa aatagaatat
    20701 tagattaaaa ttaggttctt aattagatgt taaaagggaa aaaggttaga tgcctttgca
    20761 gcccccgcta ctgtgaaacc aacgaaacta taaataccac tgtcagtttg atgggaaggt
    20821 tatagaagta ggatgaagtt aagccaggat acctgcctaa tttaatttaa aacaagaggt
    20881 cttcggggtg aaagattttt aattaatata tataaaagtc ctatctttag aagtattagg
    20941 acttttttta atttgttttt tagtaaattt taacaaggag ggatggaaag tggggaaaaa
    21001 aataatgcta caaggaacag cttcaaatgt aggtaaaagt gtcttagtag caggtttgtg
    21061 tagaatattt aagcaagatg gttatactgt tgctcctttt aagtcacaaa atatggcttt
    21121 aaattctttt ataactaaag aaggattaga aatgggaaga gcacaagtat ttcaagcaga
    21181 ggctgcgaaa atagagccaa tagctgatat gaatccagtt ttattaaaac cttctggaaa
    21241 taataaaagt caagttattg taagaggtaa agttgtagga gaaatgcctt cttctaagta
    21301 tcatgattat aaattggagt tagtagatgt gttgaaggaa acatttaata gcttaaattc
    21361 aaggtatgat attgtagtta tggaaggggc aggaagtaat gcagagataa acttaaaaga
    21421 tagagatatc tctaatatgg gtatggcaga aatagctgat gcacctgtaa taatagtcgg
    21481 agatattgat agaggaggcg tatttgcctc attagcagga acaatgcttt tattaaatga
    21541 agatgagaaa agaagagtaa aaggtgtaat aatcaataaa ttcagaggaa aaaaagagct
    21601 tttacaagat ggtgtaaaga tgctagaaga catcataaaa gtacctgtta taggagtagt
    21661 accttataca gatataaaga tagaagatga agacagtgta actacgagat ttaagaaaaa
    21721 aatgaataaa agtgatatac acatagaaat aattagaact ccacatatgt caaattttac
    21781 agattttaat atatttgaga cacaagaaga tgtaagtatt agatatgtag actatggaga
    21841 atctttagga aatccagata tattaataat acctggaact aaaagtacta tagacgattt
    21901 aacatatata agaaaaagtg gtcttgaatc gcaaatcaaa aatttacata gtcaaggtaa
    21961 attgatattt gggatatgtg gtggatacca aatgttaggt aaaaaattaa aagaccctta
    22021 tcatgttgaa agtgaaattg aagaagttga tggaataggt cttttagata cagaaacaac
    22081 gtttgagaaa gaaaagacta caacacaagt agaagctact attgttgaat gtattagtga
    22141 atacatgaat aaccttaagg gaaaaaaagt aaaaggttat gaaattcata tgggaattac
    22201 aaagcgaggt aatgatgtaa gaagtttaga tttaataact aaaaaacttg ataaagaagt
    22261 gaattatact gagggaagtg taaataaaga ggggaatgta attgggactt atcttcatgg
    22321 aatatttgat gaaataagct ttacaagagc aattttaaac aatataagaa agaaaaaagg
    22381 tttaggagaa ttagaaagca aagtaaactc ttttaatgaa tttaaggata aagagtatga
    22441 taagttggct gattttttaa gagaacattt agatatagag aaaatatatg agattatgaa
    22501 ataatgatga cctttattta taatttaggt aggaggtgta ttatgaaaaa aattttaatt
    22561 gcgggtacta atagtggagt aggtaaaaca acaatatcat taggaataat gcaagctttg
    22621 gttaagagaa atatgaaagt acagccatat aaagtagggc cagactatat agacccttca
    22681 tatcacactt ttataactgg aagacattct agaaatttag attcttatat gttagatgat
    22741 gaaaaaataa agtatatagt aaataagtcc tcaaaagatg cagatatttc agtaatagaa
    22801 ggtgttatgg gcttatatga tggctttgga atagatttag ataattgtac aagttcacat
    22861 acttcaaagg tattaaagtc acctgttata ttagttataa atggtaaatc tatggcagca
    22921 tctagtgctg ctatggtact tggatataag gaactagata aagatgtaaa tataaagggt
    22981 gttatagtaa ataatgtaaa gactaatagc cattatcaaa taattaagag ttctatagaa
    23041 aaatattgta atgttgaagt attggggtat tttcctccaa ataacaaatt ctctttggaa
    23101 tctcgacatc taggattagt tcctagtgta gaaatgaaat cactaaggga aaaattttat
    23161 accttagcag atgaaattga acactatata gatattgaca gaataattga aatatcagaa
    23221 agcgatgaat ttgagagtga ttttgatttt caaactttaa tagaaaataa taaaataaaa
    23281 gaacatgtta ataataaatc aatagctata gcatatgata aagcattcaa tttttattat
    23341 agagaaaata tagagctttt agaggaactt ggtttagaaa taaactattt tagccctctt
    23401 gaagatgtat cagtgccaaa tgcagattat atttatattg gaggaggttt tccagaaata
    23461 tttggaaaag aattagaagc aaatgagtca atgagaactt ccatattaga agcacataac
    23521 aataatatac ctatttatgc agaatgtgga ggactgatgt acctaggtga gaaactattg
    23581 aatcaagaag aacaagaatt taatatggtt ggaatattta gtggaattag taagatgaca
    23641 tcttctttaa aaagatttgg gtactgtatt ggtgtagcca aggaaaatac tcttttatct
    23701 aaaaaagggg aatctattaa agggcatgag tttcatcatt caatatttga aagtgatgaa
    23761 aaatgtgtat attcaatgag aaaagaaaga gatggaaata tagtagaaga gtgggatggt
    23821 ggttatagta aaggaaacac tttggctaca tatcttcata ctcattttta taataactta
    23881 aattgtatag aaaatttttt gaaaaaagga aatgaataaa tgagtatttt atctatttat
    23941 ataggatatg tgacagactt aattgtagga gacccatatt cttttcctca tccagtgaga
    24001 tttattggta aacttataaa ttttactcaa ggtataataa gaaaggtctc taaaaatgat
    24061 aggcagttaa aattgggggg atttatatta tggtttataa ccgttggaat aacatattta
    24121 acaacttatg ctatagtgaa gttatttagt tttaatatat tattgagtat tgtagtgaat
    24181 agttttataa tttatacaac actagccaca aaatgtttaa aagacgaagc attaaaaatt
    24241 tataatgtat taaaaactga agatatagaa aaatctagga ttcagctatc ttatatagta
    24301 ggtagggata ctactaattt aagtgaacct gaaataataa gagcaactgt agaaactgtt
    24361 gcagaaaata ctgtagatgg tataattgcg cctatgtttt atgcatttat tggaggagca
    24421 ccacttgcta tggcctataa agctatcaat acattggact caacagttgg atataaaaat
    24481 aaaaagtata aagatattgg ttttgcatct gctaagattg atgatatagc caattatata
    24541 ccagctagaa tatctgtcat tcttatgaca attggaagtt tctttttaaa ttataactat
    24601 aggaactgtt ttaaaatctc tattagagat agaaagaatc ataaaagtcc aaattgtgct
    24661 ttttcagaag gtgcagtatc tggtgctcta ggaatacaac taggaggtac caacgtttat
    24721 ttttgggaaa aagtatataa gccaacaata ggggataagc ttagggagat agataaagaa
    24781 gatataatta aaactaataa aattatgtat gcatcttcat ttgtatctat gttggtattt
    24841 acactaatat atgtgttatg taggatgatt ttaattaact taattatata aattattgtt
    24901 tgttaactta agggggacat agatgaagga tttagggcat ggtgccaatg tagatgaaat
    24961 ggcaagatta tatgggaaaa acccaaaaga aataattgat tttagttcaa acataaatcc
    25021 aaatgtatta ccaaatttag agagatacat tttaaaagga ttagaagagt gtaggaatta
    25081 tccagatata aattatacaa acttgagaga aaatatatca aaatatatag atataaatcc
    25141 agactttata atacctggca atggtgcaac agaagtgatt tatttgctta tgaagagtat
    25201 taaaaaaaaa ttggctataa taaatccgac tttttcagag tatagaagaa gtgctgagtt
    25261 aaataattta gatattatag atttagagtt agatttagaa aataacttta aacttaatat
    25321 agatataata aaagaaaata taaaaagatt tgatagttta tttatatgta atcctaataa
    25381 tccgagtggt aatgtccaag atttaaagga acttgttcat ttactagata aacataataa
    25441 ggtattaata attgatgaaa ctttcatgga atttgttgaa gatgaaagta aatatagttt
    25501 ggttaaatat atagaatcaa ataaaaatat atttataatt aaagctgtga ctaagttttt
    25561 tggtatgcct ggtttaaggc taggatatgg tcttacaagc aacactgaaa ttatgaacaa
    25621 aatttatgaa cacaaagagc catggactat caattctttt gcagatatac tatccaattt
    25681 tatttttgaa gataaagagt atattaaaaa tagtaaagaa tattacatag aagaaagaga
    25741 atatatgtta caagagttga gaaacataag aaatataaag gtctatgata cagatgctaa
    25801 ttttatcttg ataaaaatat ataaaaaaac aactaaagaa ttgaaaaaag atttgtttaa
    25861 gcaaggaaac atattagtta gagatgcgtc taattttata ggattagatg atagttttat
    25921 aagagtggct ataaaatctc atgaagataa caaaattctt atagaaaata tgaaaaattt
    25981 attgggtgat taaaatgaaa tcttatggaa tatgcccagc atcttgtgga gaatttgtac
    26041 aaggtataat tgatgatgaa gaatatttat gttcatatgc aatagatatg tattctaaag
    26101 tgtatattga agaaaaatta gtagatataa atttagggag atataagtca aggttagcaa
    26161 ttgaaaaggt atttgaaaaa tttaatttac ctaaaaaata tactaaaaat atttctttaa
    26221 atataaatag taaaatacct gttggaaaag gaatggcaag ttcaactgct gatataggag
    26281 ctactataaa ggcaacatta tcattgatag ataaagattt aagtagcgag gagatttcta
    26341 aattagcagc agaaatagaa ccaacagatt ctatatttat agataaaaat agtatattta
    26401 atcctctaaa tggaactgtt ataaaatacc taggaaatct gaccaatgcg aaagttgtaa
    26461 tacttgaacc aaacaaagta ctagatacta tgaaaattag attgaggcaa gattataata
    26521 aattaaaagt agagaataaa gaagtaataa aaaaatcatt tgctctttta gaagaaggat
    26581 tgaaaaaaaa taatttatct ctagttggag aggcttgtac tttgagtagc ttagcaaatg
    26641 agaatataga aaaaaaagag tatttaaatg aaataataaa aatatcaaaa aaatatggag
    26701 catatggagt aaatattgct cacagtggaa ctgtagtagg tattttaatt gataagttta
    26761 tgaatgataa aaagatgata gatgccttat gtgaatctaa cataaattct gtctataata
    26821 aaatttatac acaaaacata attaatggag gaattaaggg ggaaatagaa tggaatacat
    26881 aaagaatcct atgaaaatag aagaaaaaag ttttgaattg atacaagaaa taatagacga
    26941 aattagacca gattataaat ttaagaataa tatcgaagaa aaaataataa aaagagctat
    27001 acatactact gctgattttg attacttaga tatattaaaa atatcagaag aagcagttga
    27061 tagtataata gatgcattaa aaaataatgc aagtatttat actgatacaa atatggctct
    27121 tagtggtata aataaaagaa agttagaatc attaggatgt aagtataaat gtttagtggc
    27181 agatgatgaa actgtaaaat tagctaaaga aaaaggaatt actcgttcta tggcagcagt
    27241 agaaattgca gctaaagaag aaggaagaaa aatattcgtt ttaggtaatg ctccaacagc
    27301 tttatataaa gttatggaga tgaaatcaga aggtagatta gatttagatg cagttatagg
    27361 agttcctgta ggttttgtag gagcacaaga atcaaaagat gaagttgaaa aaacagatat
    27421 accatatata atttctaaag gtagaaaagg tggcagtaat ttagcagcag caatagtaaa
    27481 tgctatatta tatactatgt aggtacctat atggaagaat atgtatatat agatggaaaa
    27541 aaatatagaa gaggatatac tacaggttca tgtgcaacag gtgcatctaa ggctgctgta
    27601 tatatgttga ttacaaaaaa tagaattaat actataaata tagatactcc taaggggata
    27661 ccattactac taaaagttga taatataaat atttctgata catttgtgga atgttccata
    27721 aaaaaagatg gtggagatga tatagatgca actcatacca tggatattta tgcaagagct
    27781 gaaattgtag ctaaaaatga taagaacaaa gggtatctta ctctaaagga tatagatagt
    27841 ttaagcacca atagtgagtg taaaagtgag ctctataagt ttattagggt ttatggcgga
    27901 actggtattg gtgtggttac gaaaaaaggg cttagtgtgg atgttggtaa gcctgctata
    27961 aatccgactc cacttaaaat gataaatcat gaaataagaa agcttatagg agataatttt
    28021 gaatctatac ttggaaatga taaagtttta aaaataacaa tctttgctcc acaaggagaa
    28081 actgtagcaa aaaaaacatt taatccaaga ttaggtatag ttggaggaat atctataata
    28141 ggtacaactg ggattgttga acccatgagt gatgatggtt ggaagaagtc tctatctata
    28201 gaacttcaga tgaaaaaaga acaaggctta gataaaataa tattggttcc aggaaatcat
    28261 ggagaacagt ttataagaga aaaattaaac ttagatatta agtatgtagt tagggtaagt
    28321 aattttatag gctatatgat taaagaagct caaagaatag gatataaaaa aatcttaatg
    28381 gcaggccata taggtaaatt tataaaagta tctgctggta tttttaatac tcatagtaag
    28441 gtagcagatg ctagaagtga gatattagtg gcaaacttag ctttaatggg agctagatac
    28501 gaatttttaa ataaaataaa tcaatgcgta actactgaag aagctgtaga gctaataaat
    28561 aatagtgaat atagagaagt atataatata ttaagtaata aatgtaggga gagagtaaag
    28621 caatacttga atgaagattc agatgatatt gatgtggaag taatcatatt ttcaatggat
    28681 aagtctttat taggtaaatc ggataataca gatgatttag tggaggtctt tatatgataa
    28741 acataatagg tctaggacct ggtaacttag actatataac aaaaaaaggt gaaaatttaa
    28801 tttccacttc tgatgtatta attggtggta aaagaaattt agagtctata aaaaattttg
    28861 aaggagaaaa aatagttctg gattctaatt taagagaaat tatagagtac ataaataaca
    28921 ataaagaaaa gcaaatatca ataatagcat ctggggaccc attaatatat gggataggta
    28981 gatatctatc taaaaatatt gataataaga tgttaaacat ggtttctggg attagttcat
    29041 tacagtacat attttcaaaa atatatgtag atatgaatga tgtatatatt acaagtagtc
    29101 atggcaaagt accagatttt gattacatat tatcacataa aaaagtatgt atggttacag
    29161 attcaaagat aggaccaaaa caaataagta gagaaataat agatagaaat ctaaataaaa
    29221 ttattgttgt aggagaaaat ctgtcatatg acaatgaaaa aataacaata gcaaaaccag
    29281 aagagataat aagaatggac aattttgata tgaatgttgt ggtgatttta gatgaggaat
    29341 agtgaattta taacaggtaa agttccaatt actaaggaag aggttagagc aatatcaata
    29401 agtaagttaa atttagtaaa tgctaaaaac ctcatagaca taggggctgg tacaggaagt
    29461 gtaagtgttg aagctgcata taattatcct aatttaaagg ttatatctat agagaaaaat
    29521 gatgatgcta tagagcttat agagaaaaat aaaaaaaaat tcaacttaaa aaatatagaa
    29581 gtgataaaag gatatgctcc aattaatcta gggttaaatg ttaaagttga gtctattttt
    29641 cttgggggaa caggaaataa tctggaagaa ataatagaat ggtctaaaaa aaatctcgtt
    29701 acaggaggaa gacttgtagc taattttata ataatagata catttaatca aactttaaaa
    29761 ctgcttaaaa agcatggatt taaagaaata gatgtatgtg ttttgaatgt ttctaaacta
    29821 gagaaactag gaaaaggtga atattttaaa ccactaaatc ctatatatat aatatcttgt
    29881 gaaaaagggg aaaatgatga tgaataaagt acattttgta ggagcaggac ctggagataa
    29941 agagctgata acattaaaag gatacaaatt attaagtaat gcagatgtag tgatatatgc
    30001 aggttcactt gttaatcctg aacttttgga atactgtaaa gaagattgcc aaatacataa
    30061 tagtgcacat atggatttac aagagataat agatgttatg agagaaggta tagaaaataa
    30121 taaatctgtt gtaagactgc aaacaggtga tttttctata tatggttcaa ttagagaaca
    30181 agtggaagat ttaaataaat tgaatataga ttatgactgt actccaggag taagttcttt
    30241 tttaggggca gcatcatctt taggggttga atatacagtt ccagaaattt ctcaaagtgt
    30301 aattataaca agaatggaag gcagaactcc ggttccagag aaagaatcaa tacaatcata
    30361 tgctaagcat cagacatcta tggtaatatt tttatctgtt caagaaattg agaaagttgt
    30421 gtctaaatta ctggaaggtg gatatccaaa agatactcct atagcagtta tatacaaagc
    30481 aacttgggca gatgaaaaaa tagttaaagg aactttaagt gatatagctg taaaagttaa
    30541 agaaaacaac ataaataaga ctgctttaat aatggttggg agatttttag gagaagagta
    30601 taataattca aagttatatg ataaggattt caaacatgaa tatagagggt aatattgcta
    30661 taatctgtat tacagaaaat ggaaaaaaat tagctctaaa gataaattct ctagtaaata
    30721 actgtgttat atatcatgta aaaaataaaa aaagtaattt agttgttgaa gaaacatgtg
    30781 tgcatacagt tcaaaagaag ttaagtgatt ttgtaggaga aatatttagc aaatttgatt
    30841 acatagtatt tataatggct acaggtatag ttgtacgaag tatagcacca tacataataa
    30901 gtaagtttag tgaccctgca attttggtaa tggatgaaaa aggcaaaaac gtaataagtt
    30961 tattgagtgg tcatattgga ggggcaaaca gcttgacaca gtacataagt agtcttattg
    31021 atgctaatcc agtaataaca acagctactg atataaatca aaaagcttcc ttagatatga
    31081 tagcaaaaaa actaaatgca catattgata attttagaga aagtgtaaaa gaagtaaatt
    31141 ctatgctagt gaataataaa tgtgttggat tatatattga tgaaggatat caagttgata
    31201 ctaggggatt taaacttata gaaagtaagg atgagttaag agatagtttt tcaaacacat
    31261 atatagaaaa attagttgta gtaagcaata aaataaattg tattgaagat attgagaatt
    31321 taaacctaga taataaattt gaacattgct atagtaccaa aaaaataata aaggtaattc
    31381 caagagatat agtgatagga attggttgta gaagaaacac agatagtgaa ctgatgtata
    31441 attcacttga agagtttctt aataaacaaa atatagatat tagagcaata aacacagttg
    31501 gaagtataga actgaaaaaa gacgaaaaag caataattga attatcaaaa atattgaagg
    31561 tgccatttaa aacattttca gtagatgaaa tatctaaggt tgataatctt tttgataaat
    31621 ctgattttgt taaaaaaaat gtgggcgtgt attcagtagc agaacctgta gcatatcttt
    31681 tgagcaaagg taatttgtta gttgaaaaac ataaatataa aggaataact ttttcagtgg
    31741 ggagaataaa aatatgatat acgttgtagg aattggacca ggaagtaaag atacaatgac
    31801 tttagaagca ataaaagcaa tagaagattc tgaggctatt gttggatata agacttatat
    31861 aaaactaata gaagaattta tacaagataa agaaataatc caaaatggta tgaggcaaga
    31921 agttgataga tgtaaacaag cagtagagga agcaaaaaaa ggaaaaaaag tagcagttgt
    31981 aagcagtggt gatgctggaa tatatgggat ggcaggtctt attttagaat taatatctaa
    32041 agaagatgaa gatataaaag taaaggtaat tccaggtgtt actgcaagta ttggtgcagc
    32101 agctatactt ggagctccta ttatgcatga tttctgtcat ataagtttga gtgatttaat
    32161 gactccgtgg gaagtaattg aaaaaagatt gagattggcc gctgaagccg attttgtaat
    32221 ttgtttgtat aatccaagaa gtaagggaag aagtgaacat ctaagcaaag catttaaaat
    32281 aatgggtgag tttaaaggtg gagatacacc tgttggagtg gtaaaagatg taggtagaga
    32341 aaaagaagaa aagtttgtat gtacttttga aaatatggac tttgaaaaag tcgatatgac
    32401 tacaatggtt ataataggaa ataagtctac ctatattaat ggtgaattga tgataactcc
    32461 aagaggttat acagtatgat tttaatttta ggaggaactt cagatagttt atctatatgt
    32521 gataagataa atgaactgaa aaatcaacca tatatccttt cagttactac agattatgga
    32581 agggaacttg cacaacaaca tgcagagaat gtaattttag gtaagcttgg aaaagaagat
    32641 atgctaaaat ttataaaaga taataatata gtaaaaataa tagatgccac tcatccttat
    32701 gcagttgaag tatccaaaac tgctattact tgtgcaaaac tattgaatat agattatata
    32761 aggtttgaga gaaaatcttt aattgaagaa atagattatg ataataaatt tatagtagat
    32821 acaattgaag aagcctgtga aatagcaaat aaaataggga caaatatatt cataggaaca
    32881 ggaagtaaaa atttgaacag atttatagag gaaataagtg ataaaaattt agttgttaga
    32941 gttcttccaa cgagtgaagt catattaagt tgtgaaaaat taggtttaag tgcagataat
    33001 atagtagcta tgaaaggtcc atttagccag tatataaatg aagaaacata taaacattac
    33061 aatatagatt tagtcataac aaaagaaagt ggaatagctg gtgggttctt agagaaggta
    33121 aatgcatgta aaactttcaa tataccagta ataattataa aaagagaatc gattaactac
    33181 gaaaatgtat ttaatgacat aaataaaatt aaagacatac ttgtgtaatt tttaggagga
    33241 gaatatatga agaaagcctt attagtagtg agttttggta caagctatca tgaaacgaga
    33301 gaaaagacaa tagatatatg tgaagataaa ataaaaaatt cgttaaaaag ccatgatttt
    33361 tttagagctt atacatcaaa tatgataata aataaaataa aaaaaaggga tggaatagaa
    33421 atagataatc caatacaggc tttagataaa atatatgaac aaggatatga tgaagtaata
    33481 atccaaacac ttcatattat atgtggcgaa gaatttaaca aattaaaaga acaagtagat
    33541 ggatattctt ctaaattcaa aaagattgta ttaggaagac ctttgcttac acatattgaa
    33601 gattatcagg aagctgtaga ggcaattaag catcaaattc ctcatatgga aagtaatgaa
    33661 gcagtagtat ttatgggaca tggaacactt catgaatcac attcagcgta tccagcattg
    33721 gaatacatgc ttagggataa tggaataaat gcttatgttg gtacagttga agggtatcca
    33781 gaaatagaac atgtaataag aagattaaaa gaaggaaata taaaaactgt aaatttgatg
    33841 ccatttatgt tagttgcagg agaccatgct ataaatgata tggcaggaga tgaagaagat
    33901 tcttggaaaa caatattaga agaaaatgga tttaacgtaa gagttcattt aaaaggacta
    33961 ggagaaaatt cttatataca agataaattt gttcgtcatg ctgtaaaatg tgcagagaat
    34021 gcgaagttct atggtatagg agcagggcca ggagatggtt ctttacttac gataaaagcg
    34081 gttaatactt taaagaaact ggatattcta tacactccag aatcaaaaaa gggtggagat
    34141 agtctagctt tatcaatagt tagtgaatat ttacctgaat cagtggaaat aaagtctagg
    34201 catttcccaa tgagttttga tgggaatgaa aaaagtttag cttgggacaa tgtggcacaa
    34261 gaaattatat cagatgttaa tgatggtaaa aatgtaggat ttgttacatt aggagaccct
    34321 atgatttata gtacatatgt atatataatg aaaagaatat taggagaggt agaagtcgaa
    34381 actataccag gaatttcatc attttccaat atagcatcta atcagaattt tccattagtc
    34441 atggataaag aagctttagt ggtaattcct tgtactatgg aagatgataa gatagagtat
    34501 gctttgcaaa attataattc aatagtattg atgaaagtat ataaaaattt taaagaaata
    34561 ataaaaaaat tagaaaagta tgatttaata gaacatgcta ttttagtaag taattcttcc
    34621 caagaaagcg aaaatgtgtt tacagattta aaagaagcgc accttgaaga taagatatct
    34681 tatttttcta ctatactagt aaataaagat aataaaataa aataggtgaa agcaatattt
    34741 aaaggagact taatatgaat atagtggttg gaactagggg tagtaatcta gcgcttatac
    34801 aaacagaatg ggtaataaat gaattaaaaa agaagtatcc agaaattagt tttgagatta
    34861 aaatcataaa gacaaaagga gatttaattc aaaatgtttc actggataaa ataggtgata
    34921 aaggattgtt tgtcaaagaa atagagcaac aattattaga tggaaaaata gacatagcag
    34981 tacatagtat gaaagatatg ccttcttatt tagcagatgg actaaaattt gctcatacgc
    35041 ctaagagaga agacccaaga gatgttctaa tacttagaga aggatataaa aatttagatg
    35101 atttacctca tggagcagta ataggaacag gaagtaaaag aaggaagttt caattattga
    35161 aacaaagacc tgatttaaat atagtacaag ttagaggtaa tgtggaaact aggatacgaa
    35221 aaataaaaga tgaaaacatg catggtattg tgttggcagc atcaggaata attagagcta
    35281 atttgcaaga taaaataagt tcttatttac ctgttgatgt tgttattcca gcacctgccc
    35341 aaggagcttt agctatagaa attagaagca atgatagtgc gatagaggga atagtaaatt
    35401 cactgaagga tgagaataca gaaatccaaa tattggctga aagaggtttt ttagatggtg
    35461 taaatggaag ttgtcatatt ccaatggcag cttattgtga aataatccaa gataaaatac
    35521 atcttactgg cttatatgga gattcagaag gaaaaaaagt agtaatcaag tctatagatg
    35581 gagatatttc ttctcctaga gagttaggtt taaagttagc taaacttgta ttgaaggagt
    35641 atgagaatta tgaagggtaa ggtttactta gtaggggcag gaccaggtga ttataaactc
    35701 atgactttaa aaggtttaga gtgtataaga aaatcggatg taatagtata tgatagatta
    35761 gcaaatagta gttatttaag agaagctaag cctgattgtg aacttatata tgtaggcaag
    35821 gcatcaagta atcatatttt gccacaagaa gatataaata gaattatagc agaaaaagct
    35881 aaagaaggaa aaattgtaac tcgtcttaaa ggaggagacc cttatgtatt tggcagaggg
    35941 ggagaagaag cagagacttt agtagatgaa ggtatagaat ttgaagtagt tccaggtata
    36001 acttctgcta taggaggttt atgttatgcg ggtattccta taacacatag agaccatgct
    36061 tcgtcatttc atgtaataac aggtcatttg aagggtgatg atagtggaga actaaactgg
    36121 aatgctcttg caaataacaa aggtactctt gtgtttttga tgggaatttc aaacctagag
    36181 aaaataagtg aaaacttaat gaaagaagga aaagataagg atacacctgt tgctcttata
    36241 agttgggcaa ctagatataa tcaaagagtt gttacatcta cacttgaaaa tgtttatgaa
    36301 actgctatta aagaagaagt aaaaccgcca actcttatag tagttgggag tgttgtagga
    36361 cttagagaaa agttgaactt ctttgaaagt aagcctttat ttggaaaaag tattgctgta
    36421 actaggtcta gaaatcaaaa tagtgtattg gtagaaaaaa taatggattt aggtggaaat
    36481 cctatagaaa tacctactat taaggtagaa aaaatacaaa ataatattaa cttagaaaat
    36541 gaaataaaaa atataaataa gtataattat ctaatactaa ctagtaaaaa tgccgtagaa
    36601 atcttctttg aaaagatata tgaaatgaat tttgatttaa ggatattatc taatttaaag
    36661 gtatgtgcta taggttctgc tacatcaaat gagttgaaaa aaagaggaat tatagcggat
    36721 atagtaccaa aaaaatttgt agcagagtca ctgtatgaag agttagcgcc tattttaaat
    36781 gatgacgata atatacttat acctagagca gaaaatgcta gagattatct ggttgacaaa
    36841 cttaaggcta tttgtgaagt aacagaagta catatatata gaacagtaat agatgaggag
    36901 aaaaaaggtg agatattaga tattttaaat tctaatgaca tagattatat aacatttact
    36961 agttcctcaa cagtaaataa tcttgttgaa attataggaa aagaaaatat taaaatatta
    37021 gaaaaaataa aaacactatc tataggtcct ataactacag agacaataaa tagtttggga
    37081 ataaaattgt acaaagaatc tgctacatct actatagatt cgttagtaga tttaattata
    37141 aaaaattaat tttggaggct tgaatatgtt aagaagacca agaagactaa gagcaagtaa
    37201 agcaatcaga aatttggtaa gagaaactaa ggtgaatgta gaagacttaa tatatccact
    37261 gtttgtagta gagggggaaa atataaaaga agaaattaaa tctttaccag atgtctatca
    37321 tttatcaata gatatgctag aagacgaaat aaaagaaata agtgagttgg gaattgaaca
    37381 tataatgtta tttggtgttc cagatgaaaa agatgagtgt gcttcacaag cttttaatga
    37441 taatggaata gttcaaaagg caattagaaa ggtaaaagaa ataaattcag atataaatgt
    37501 aataacagat gtctgtatgt gccaatatac aagtcatgga cattgtggga ttttaactga
    37561 tactggttat gttgataatg ataaatcatt ggagtatttg gctaaaatat ctgtaagcca
    37621 tgctaaagca ggagctgata tggttgctcc atctgatatg atggatggaa gaatacaagc
    37681 aataagagaa gctttagatg aaaatggatt agaaaatgtt ggaatcatgg cttatagtgt
    37741 taagtatgct tcaaattatt atggaccttt tagagaggca gctcattcag caccatcttt
    37801 tggagataga aaaacatatc aaatggaccc agcaaatagc aatgaagcta taatagagac
    37861 tgaacttgat atattggaag gtgcagatat acttatggtt aaacctgcat tatcatattt
    37921 agatattata agaagagtta aagataattt tgacttacct ctagcagctt ataatgtaag
    37981 tggagaatac tctatgctta agtttgctgt gaaggaaggt ttattaaatg aagatgtaat
    38041 tcttgaatca attacatcta taaaaagagc aggagcagat ataataataa cttattttgc
    38101 taaagacatt gctaaactgt tgaaaaaata aattctagca gtataaagaa tatcaaaaag
    38161 tataggaatt gtaattaact attatacagt agttttgttt agacatttat tgaagaataa
    38221 tagaaactaa tttgcaattt ctatacttta tttatgtaac taaataaaat ttggaggtag
    38281 aagatgctat atcctattaa tttaaaatta gatgagttag atgtagttat aattggtggt
    38341 ggagaagttg catataggaa atgtaaaaat tttttagagt ttaacaaaaa tgttactata
    38401 gtttctaaac aaattttaaa taaattttat gatttaaaag gaaatataaa aataataaaa
    38461 gatgattata aagaaatata tataaaagat gcttctgtaa taattgctgc cacaaataat
    38521 agagagttaa atatggaaat aggattatat tgtaaagcaa aaaataagct agtgaatgta
    38581 gttgataata tagaaatatc gaactttact gttccatcat atataaaaag aggagattta
    38641 cttataagtg tgtctactgg gggcaagagt ccttcattat catcaaagat aaaaaaagaa
    38701 attgaagaga gatatactga agattatgag gagtatttaa atgtattagg agatataaga
    38761 aaaaaggtta taaaaaaata cgaagataaa agtaaaagaa aagatgtgct taatatgttg
    38821 gtaacacttg acctagaaga acttaagaag tttgatatat aaaaaataaa ataaaaaatg
    38881 ttaaaaaggt gttgacggat
//
LOCUS       DAGQVA010000033        38441 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.033, whole genome shotgun sequence.
ACCESSION   DAGQVA010000033 DAGQVA010000000
VERSION     DAGQVA010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38441
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.033"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..416)
                     /locus_tag="MIV85_001870"
     CDS             complement(<1..416)
                     /locus_tag="MIV85_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBY2961211.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKKVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNT"
     gene            complement(494..811)
                     /locus_tag="MIV85_001871"
     CDS             complement(494..811)
                     /locus_tag="MIV85_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961212.1"
                     /translation="MKSLTIVRNAVEQQLNRANLEINKNEELYTKLRKKEKRDVLDEI
                     ELSNALREKSVNERLKIFAESLLKIIDTQIEIKEYEESEDYKIFELISEEIERDRPID
                     IQI"
     gene            complement(814..960)
                     /locus_tag="MIV85_001872"
     CDS             complement(814..960)
                     /locus_tag="MIV85_001872"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961213.1"
                     /translation="MNVRVLIAYVQFCNDKQIKASFEGLRKYNRDIELVNLYLPSKLK
                     IKGD"
     gene            complement(961..1404)
                     /locus_tag="MIV85_001873"
     CDS             complement(961..1404)
                     /locus_tag="MIV85_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2961214.1"
                     /translation="MSKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKEIREGVI"
     gene            complement(1434..1631)
                     /locus_tag="MIV85_001874"
     CDS             complement(1434..1631)
                     /locus_tag="MIV85_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961215.1"
                     /translation="MAINDNINKILRDRNLKAWKLAKEIGIDSGNLYAILRGENKNPT
                     IDTLIKIADYLDVTLDELVGR"
     gene            1700..1933
                     /locus_tag="MIV85_001875"
     CDS             1700..1933
                     /locus_tag="MIV85_001875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961216.1"
                     /translation="MTIDKITKIEATCLDCDTKVIITESKFREVCDNGLTCPMCKEHI
                     SNSNFIAEQALQYNYVINDLKKELDSCKNIRIY"
     gene            complement(1937..2107)
                     /locus_tag="MIV85_001876"
     CDS             complement(1937..2107)
                     /locus_tag="MIV85_001876"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961217.1"
                     /translation="MKNNTSDSRVKYFCKCPYCGFDNEVEVKKGLKPKICCICTKEVE
                     YEKLEQQSTPAK"
     gene            complement(2196..2987)
                     /locus_tag="MIV85_001877"
     CDS             complement(2196..2987)
                     /locus_tag="MIV85_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBY2961218.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDVNNIQTNFNRNKERFKE
                     NVHYFLLQGEYLKEFKNQPTNSQLVSKHSSQLYLWTERGANRHCKILDTDKAWEQFDN
                     LEETYFKVKQQKPSCIEDVLIESLKEMKDLRLQVNQANNIALEAKTEVKTIKEVVSLN
                     ATDWRKDTQQLIARIAKKQGGFEHINMLRTESYELLNKRFGVDLHRRLINKRRKMAEE
                     GISESKREKVNNLDVIQDDKKLIEGYVSIIKDMALKYGISDLSKN"
     gene            complement(3021..3209)
                     /locus_tag="MIV85_001878"
     CDS             complement(3021..3209)
                     /locus_tag="MIV85_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009587961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961219.1"
                     /translation="MKELSKFRKNLGLTQKQLAERIGISKSYYSKIEGNFKKPGRGFL
                     EKFKNTFPNEDMNIFFKQ"
     gene            3353..3703
                     /locus_tag="MIV85_001879"
     CDS             3353..3703
                     /locus_tag="MIV85_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961220.1"
                     /translation="MTRSDIMFSNRLRELRKQKGLTQMELAKLLNCSLSKIAMLETDK
                     RDPVKEDLLRFSEIFEVSIDYLLGKNNLDLNPRLNKEMEQALHKLYSLDEENRKAIEK
                     IIDNAYYKIINEEK"
     gene            4128..4349
                     /locus_tag="MIV85_001880"
     CDS             4128..4349
                     /locus_tag="MIV85_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961221.1"
                     /translation="MLKELRKKKKLTQIELAKRVGCHRSQISRLENNEDKDLTIPILI
                     ELEIALGLEEKYLVNYFADEYIKKRKLHK"
     gene            4408..4614
                     /locus_tag="MIV85_001881"
     CDS             4408..4614
                     /locus_tag="MIV85_001881"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961222.1"
                     /translation="MNLSFNKKKKFELSKEELELIENWLGNKYAGDMTIPAIVDFSLE
                     TDIEYEKIVVYLAEKVLESRDKKH"
     gene            4752..5918
                     /locus_tag="MIV85_001882"
     CDS             4752..5918
                     /locus_tag="MIV85_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBY2961223.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDAAIRTINKKLNINFNFHCL
                     RHTHATLLLENGANVKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILEGILQ"
     gene            complement(6026..6211)
                     /locus_tag="MIV85_001883"
                     /pseudo
     CDS             complement(6026..6211)
                     /locus_tag="MIV85_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(6451..7845)
                     /locus_tag="MIV85_001884"
     CDS             complement(6451..7845)
                     /locus_tag="MIV85_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBY2961224.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(7865..8074)
                     /locus_tag="MIV85_001885"
     CDS             complement(7865..8074)
                     /locus_tag="MIV85_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBY2961225.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(8103..9548)
                     /locus_tag="MIV85_001886"
     CDS             complement(8103..9548)
                     /locus_tag="MIV85_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBY2961226.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            9658..10452
                     /locus_tag="MIV85_001887"
     CDS             9658..10452
                     /locus_tag="MIV85_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBY2961227.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            10503..11825
                     /locus_tag="MIV85_001888"
     CDS             10503..11825
                     /locus_tag="MIV85_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBY2961228.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(11925..13142)
                     /gene="cdeC"
                     /locus_tag="MIV85_001889"
     CDS             complement(11925..13142)
                     /gene="cdeC"
                     /locus_tag="MIV85_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBY2961229.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(13325..13505)
                     /gene="ssrS"
                     /locus_tag="MIV85_001890"
     ncRNA           complement(13325..13505)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="MIV85_001890"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(13620..14525)
                     /locus_tag="MIV85_001891"
     CDS             complement(13620..14525)
                     /locus_tag="MIV85_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961230.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            14737..15135
                     /locus_tag="MIV85_001892"
     CDS             14737..15135
                     /locus_tag="MIV85_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961231.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            complement(15258..16274)
                     /gene="ccpA"
                     /locus_tag="MIV85_001893"
     CDS             complement(15258..16274)
                     /gene="ccpA"
                     /locus_tag="MIV85_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBY2961232.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(16527..16727)
                     /locus_tag="MIV85_001894"
     CDS             complement(16527..16727)
                     /locus_tag="MIV85_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961233.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(16761..16940)
                     /locus_tag="MIV85_001895"
     CDS             complement(16761..16940)
                     /locus_tag="MIV85_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961234.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(17122..17328)
                     /locus_tag="MIV85_001896"
     CDS             complement(17122..17328)
                     /locus_tag="MIV85_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961235.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(17376..17801)
                     /locus_tag="MIV85_001897"
     CDS             complement(17376..17801)
                     /locus_tag="MIV85_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961236.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            17973..18200
                     /gene="acpP"
                     /locus_tag="MIV85_001898"
     CDS             17973..18200
                     /gene="acpP"
                     /locus_tag="MIV85_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBY2961237.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(18344..19348)
                     /locus_tag="MIV85_001899"
     CDS             complement(18344..19348)
                     /locus_tag="MIV85_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBY2961238.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(19362..20264)
                     /locus_tag="MIV85_001900"
     CDS             complement(19362..20264)
                     /locus_tag="MIV85_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBY2961239.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEDLINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(20460..21635)
                     /locus_tag="MIV85_001901"
     CDS             complement(20460..21635)
                     /locus_tag="MIV85_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBY2961240.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(21722..22567)
                     /locus_tag="MIV85_001902"
     CDS             complement(21722..22567)
                     /locus_tag="MIV85_001902"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBY2961241.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(22665..23462)
                     /locus_tag="MIV85_001903"
     CDS             complement(22665..23462)
                     /locus_tag="MIV85_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBY2961242.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(23481..24491)
                     /locus_tag="MIV85_001904"
     CDS             complement(23481..24491)
                     /locus_tag="MIV85_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBY2961243.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(24510..25292)
                     /locus_tag="MIV85_001905"
     CDS             complement(24510..25292)
                     /locus_tag="MIV85_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBY2961244.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(25351..26487)
                     /locus_tag="MIV85_001906"
     CDS             complement(25351..26487)
                     /locus_tag="MIV85_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBY2961245.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(27196..27663)
                     /locus_tag="MIV85_001907"
     CDS             complement(27196..27663)
                     /locus_tag="MIV85_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBY2961246.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(27742..28284)
                     /locus_tag="MIV85_001908"
     CDS             complement(27742..28284)
                     /locus_tag="MIV85_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961247.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(28336..29022)
                     /locus_tag="MIV85_001909"
     CDS             complement(28336..29022)
                     /locus_tag="MIV85_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBY2961248.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(29022..29882)
                     /locus_tag="MIV85_001910"
     CDS             complement(29022..29882)
                     /locus_tag="MIV85_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961249.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            30017..30817
                     /locus_tag="MIV85_001911"
     CDS             30017..30817
                     /locus_tag="MIV85_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBY2961250.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            30842..31411
                     /gene="yfcE"
                     /locus_tag="MIV85_001912"
     CDS             30842..31411
                     /gene="yfcE"
                     /locus_tag="MIV85_001912"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBY2961251.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(31829..32881)
                     /locus_tag="MIV85_001913"
     CDS             complement(31829..32881)
                     /locus_tag="MIV85_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBY2961252.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADNISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(33088..34314)
                     /gene="pepT"
                     /locus_tag="MIV85_001914"
     CDS             complement(33088..34314)
                     /gene="pepT"
                     /locus_tag="MIV85_001914"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBY2961253.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPKIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            complement(34404..35456)
                     /gene="ytvI"
                     /locus_tag="MIV85_001915"
     CDS             complement(34404..35456)
                     /gene="ytvI"
                     /locus_tag="MIV85_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBY2961254.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            complement(35605..36858)
                     /locus_tag="MIV85_001916"
     CDS             complement(35605..36858)
                     /locus_tag="MIV85_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBY2961255.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            complement(36989..>38441)
                     /locus_tag="MIV85_001917"
     CDS             complement(36989..>38441)
                     /locus_tag="MIV85_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nuclease SbcCD subunit C"
                     /protein_id="HBY2961256.1"
                     /translation="VTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCK
                     KLKQEYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENES
                     KLHEIEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEE
                     SSKKKLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKR
                     ALLDTDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKV
                     EIGNISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEY
                     VSTNQLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETF
                     LTSLSLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGI
                     ISHVEELKNRVPVKLLVSSSEAGIGSKVKIEYS"
BASE COUNT        12375 a         6631 c         4202 g        15233 t
ORIGIN      
        1 gtgttcttat ctacttttac aacttgctct actgttttat atatagcagg tatcttttct
       61 tcatcttcta tgactaagct acctgctgac tttcttatac ttatatttcc taaaactgtt
      121 tctacttttt tagtcccaag taattccata cagtctttta tattgctttt taatctatca
      181 agagtattct tcttaacctt ctttaactct tgtaacctct taatctctga atctatagag
      241 tttatatcac tgtcaatgtt taatattact gacactattc tagtgttttt attttgtatc
      301 tcttgtttta ttatttcttt tatttcctct agtttttcag cttcatttcc tgttgtttct
      361 gttaaacctt cttctatttc taataaatct gtagttaatt catataaagt actcataatt
      421 tccctccgtt tgtgctataa ttagcttata ttttatatta ttttggaatc gagccactcc
      481 taatggctct tttctatatc tgaatatcta taggtctatc tctttcaatt tcttctgaaa
      541 ttaattcaaa tatcttgtaa tcctcgcttt cttcatattc ttttatttca atttgtgtat
      601 ctataatttt tagtaatgac tcagcaaata tttttaatct ttcatttaca cttttttctc
      661 ttaaagcatt acttaactct atttcatcta atacatctct tttttctttt tttctaagtt
      721 ttgtataaag ttcctcattt ttatttattt ctaaattagc tctatttagt tgttgctcta
      781 ctgcatttct tactatagtt aaacttttca tgattaatcc cccttaattt ttaatttact
      841 tggtaaatac aagttaacta actctatatc tctgttgtat tttctaagac cttcaaaact
      901 tgcttttatt tgcttatcat tgcaaaactg tacataagct attagtactc ttacattcaa
      961 ctaaatcacc ccctctctaa tttctttcat ttctctaagc atttctttga tgttttttcc
     1021 ttgatttcta gttataaaat catctaattc ataactagaa actttagttg cccctatatc
     1081 aactgacttc aaaagcccat tttttattaa ctcatatcca aatactttat ctattttcaa
     1141 tcttttactt gcttcttcaa cagacataag ataatcggga taacctttac ttataacaat
     1201 tgttagttct tttggttcta ataattctat tttcgaagtt tcatttaagt actttgagat
     1261 tttattttta tagttgttta aattcatttc tacaacttta cggatacctt ctgaaaaaca
     1321 aattgatata ttatctaggt cattaaaact tttatcttct tgtttatcta aattgaaatt
     1381 agatatattg cccaatttac tcactccttt tcaaaatatt ctgtatttaa tttttatctt
     1441 ccaactagtt catctaatgt aacgtctaaa tagtcagcta tttttattaa tgtatctata
     1501 gttggatttt tattttctcc tcttaaaatt gcatataaat tccctgaatc tattcctatt
     1561 tcttttgcta atttccatgc ttttaaattt ctatctctta aaattttatt tatgttgtca
     1621 ttaattgcca ttactttcct cctttgatat actatatttg taggataaat cctataaata
     1681 tattgttagg tggtgactta tgactattga taaaataact aaaattgaag ctacttgttt
     1741 agattgtgat acaaaagtta tcataacaga atctaaattt agggaagttt gtgataatgg
     1801 gctaacatgc cctatgtgta aagaacacat atcaaattct aattttatag cagaacaggc
     1861 actgcaatat aattatgtta ttaatgattt aaaaaaagaa ttagattcct gtaagaatat
     1921 tcgtatttat taatttctat tttgctggag tactttgttg ctccagtttt tcatactcca
     1981 cttcttttgt acatatgcaa catattttag gcttcaatcc ttttttaact tctacctcat
     2041 tatcaaaccc acagtatgga cacttgcaaa aatattttac tcttgaatcg cttgtattat
     2101 ttttcatgta tttaacctcc tagttaataa ttaattaaaa caatatattt caaaatattc
     2161 tgtatttaat tttcaaggta ctgttatgat ttaacctaat tcttgcttaa atctgatatt
     2221 ccatatttta gagccatatc ttttataata gatacgtaac cctctatgag ttttttatca
     2281 tcttgtatta catctaaatt attcactttc tctcttttag attcagatat accttcttcc
     2341 gccatttttc ttctcttatt gattaatctt ctatgaaggt cgactccgaa tctcttattt
     2401 aataattcat aactttctgt tctaagcata tttatatgtt caaatccacc ttgtttcttt
     2461 gctattcttg caattagttg ttgtgtatct tttctccagt cagtagcatt taatgaaaca
     2521 acttctttta ttgttttaac ctctgttttt gcttctaatg caatgttatt agcttggtta
     2581 acttgtagtc ttaaatcttt catttctttt aaactttcta ttaatacatc ttctatacaa
     2641 gatggttttt gttgcttaac tttgaaatat gtttcttcta agttatcaaa ctgttcccaa
     2701 gctttgtcag tatccaatat tttgcagtgt ctgtttgctc ctctttcagt ccaaagatat
     2761 aattgactag aatgttttga aaccaactga ctattagtag gttggttctt aaattctttc
     2821 aaatactcac cttgtaataa aaaatagtgt acattctctt tgaatctctc tttgtttcta
     2881 ttaaagttag tttgtatatt gtttacatcg gtttcataaa catctgctaa ttgctgtgta
     2941 gttagaactc tttcgttatt tctttctatt acttgtaagt tattcatttt ataatcctcc
     3001 ttacatcact ttaagtgata ttattgttta aaaaaaatgt tcatatcttc atttgggaat
     3061 gtatttttaa atttctccaa aaatcctctt cctggctttt taaaatttcc ttctatcttt
     3121 gaataataag acttagatat gcctattctt tcagctaatt gcttttgggt taatcctaaa
     3181 ttttttctaa actttgataa ctctttcatg ttacacctcg ccttcactat ttgtgataaa
     3241 tcaataatat cactttaagt gaatatagtc aagacttttt atctcttttc gtgaagtttt
     3301 ttaaaaaagg atttatttgt atcactgtta gtgatacaat cgtagtataa acatgacaag
     3361 gagtgatatt atgttttcta atagattaag agagttgcga aagcaaaaag ggttaacaca
     3421 aatggagttg gcaaaattat taaattgttc tttgagtaaa attgcaatgc tagaaacaga
     3481 taaaagagac cctgttaaag aagatttatt aagattctca gaaatttttg aggtatcaat
     3541 tgattatctt ttaggaaaga ataatctaga cctaaatcct cgattaaaca aagaaatgga
     3601 acaagctttg cacaaattat attccttaga tgaggagaac aggaaagcaa tagagaaaat
     3661 tattgataac gcttactata aaataataaa tgaagaaaaa taaaagagct ttttacactc
     3721 ttttattttt tttactcatt tcttcttcta ttaattttat tatgtattca tactttttgg
     3781 gttctgcttt aagaatcttt tctaatttaa atctattttt ttcaaaatat tcttctttat
     3841 tcaaatgtac catcccctat aaaatatttt atttattaat ttcacaaaac atacgttctt
     3901 aaaaatagtt acaaccacct ctttttcaaa gcttaaattt ataaaataac tgtaaaatat
     3961 tattatattt tatagcttct attatttttg ctttatctag ataaagttat ttcttaacta
     4021 cattctagca caaatttcca acaaaaagtg tgcgaatatt gcacatttat tacaagaaat
     4081 tacacaaact aacatatata aaattatcta aaaggtaggt taaatatatg ttaaaagagt
     4141 tacgaaaaaa gaagaaatta acacaaatag agttagcaaa aagagttggt tgccacagaa
     4201 gtcaaatttc taggttggaa aataatgagg ataaagattt aactatccct attcttattg
     4261 aattagaaat agctttagga ttggaagaaa aatatttagt aaattatttt gctgatgaat
     4321 atattaaaaa aagaaaatta cataaataat tcgaatgttt ctatcaaata ctatttttaa
     4381 tatataatat tatttgaggt gaataaattg aacttaagtt ttaataaaaa gaaaaaattt
     4441 gaattaagca aagaagaatt ggaattaatt gaaaattggt taggtaataa atatgcagga
     4501 gatatgacga tacctgctat tgttgacttt tctttagaaa ctgatattga gtatgaaaaa
     4561 atagttgttt atttggcaga aaaagtgctg gaatcacgtg ataaaaaaca ttaaatatgt
     4621 atctaaataa aaaagactat taattataaa cataaaactt tgtttcttat agtctttttt
     4681 atttatttta tttaaattga tatatgttat tatataatta cataaaaaaa gcttttgaga
     4741 ggagagattt tatgaaaggc ggcgtaagaa aacgtggaaa gaagtggtat tactactttg
     4801 atgcaggtat agtagatggc aagagaaaaa aggtagaaag agttggtgga aacactaaga
     4861 aagaagctga aaaatcgctc cgtgatgcaa taaatgaata tgaaaatgct ggtatagtgt
     4921 ttgatgaaac aaatatgagt ttatcagact atcttaactt ttggtacaaa gagtatgtac
     4981 ttcttaattg caaatacaat actcaggaaa gttatagaaa tttaattgaa aatcatatag
     5041 aacctagact tggtaaatgt aagctaaaat ctataaatcc agctattatt caagaatttt
     5101 taaataataa atcaaaagag acatacacac aaaacggaga agaaaaacac tacacaaaag
     5161 gagttttaaa agcgatttat gttgtattaa atgctgcttt aaaatctgct gtttaccctt
     5221 acaaactcat taaggaaaat cctgttcaat atgccagtat accaaaaaat gttttaaagg
     5281 taaaaaatga gtcagataac aagactataa cactagatga gttcaataaa atactagaaa
     5341 tatatcctaa aaatacaaat atctatattc ctctacttat agggtttcat acaggcatga
     5401 gaaaaggaga aatattaggt ctttgttggg ataatgttga tttagataat aatataatca
     5461 aagttagaaa aaatttaata aagagaaaag tttcagaatt tgaattagca tcacctaaga
     5521 caaaaacatc aataagagat attaaaatag gtgatacttt gtctaggata ttaaaagagg
     5581 aaaaattgaa tcaaaaaaaa caaaaaatta aaattggaaa atggtataaa gaaactgagt
     5641 atgattgggt ttgtagaaaa aaagatggct catttgtaaa tcacaacaat attgacgctg
     5701 ctataagaac tattaacaag aaactaaata ttaactttaa ttttcattgc ttgcgacata
     5761 cacatgccac attattatta gaaaatggag ctaatgtaaa atatatacaa caaagattag
     5821 gtcatagtca attatcaacc actatggaca catattcaca tgttacaagt aaaatggaaa
     5881 gtgaaacaat agatattttg gagggcattt tacaataatt tgccaccgaa aaaagttatg
     5941 gtggcaaaca ggtggcaaaa cgataaaaaa cattcttttt tttgctcaaa cactgttatt
     6001 ttgctatttt atataaaaaa gtcgtatttc tcacagttat acgacttata ttaaattctt
     6061 tacataagtc tccttcagat ggaagtttat ctcctggttt atatatgcca gatgctattt
     6121 gtttttttat gttgtcatat agttgttgat ataaaggaac aaaggaattt acttctaaat
     6181 ccatttcttt tttttgtctc ttttcatcca ttttgctcac ctccctatgt aacattttta
     6241 taacattata taacaagttc tttattacat attataacaa gatgaaatcg ttgtcaattt
     6301 tttttaaaat aatttttaat ttgacagtat tttcttttat tttctctagt gtgacaaatt
     6361 gctattttta cataaaaata agactgttgt acaacagatt aaattgttta tacaacagcc
     6421 tttattcact tattacattt atatttttac ttataaattt atattaaaaa atgccttata
     6481 tcccttatac atttcatata tgtctacttt agagacaatc tcatgtggtg catgcatatt
     6541 taaaactcca acaccacagt ctataacctc tgcaccttga tttgccaata tatgggctat
     6601 agttccgcct cctccttggt ctacttttcc aagttcagca gtttgccata ctacatttcc
     6661 tttattaaaa attctcttta cttctgacat aaattcagca ttagcatcat tacatccact
     6721 ctttcctctt gaacctgtat acttagttaa aactactcca tttcccatat atgccgaatt
     6781 tctcttttca tatgcttctc caaaatttgg gtcatatcca gcagaaacat cagctgataa
     6841 taccttacta tttgctaaag ctcttcttac tttaatatca caataatctc cttctaaagc
     6901 aatcagttca gccacagtat tttcaaaaaa ctttgagtgc atacctgtat tccctttaga
     6961 accaatttct tctttatcta cacataatgc aactgaagta aattctggtt gttcagtttc
     7021 tagtatagct tttacagcag catatgaaca taccctatca tcatgcccat atcccaacac
     7081 catagaccta tcaagcccta aatctctagc cttaccagct ggaactactt caatttcagc
     7141 acttaataaa tcttcttcaa ctatattgta tttctcattt aaaatcttta atatatttgc
     7201 tgttataggt tctttttctt catcttctaa aggcatattc ccaattaata tatttaaagc
     7261 ttctccacta attccttctg atagtttctt ttgcatttgg tctccagcca aatgaatcaa
     7321 taaatcagtt acacaaaata ctgggtcact atcttcttcc ccaatagata tgtccacttt
     7381 tgttccatca tttaatataa ctataccatg taaagcaagt ggaatagccg tccattggta
     7441 tttttttatt ccaccataat aatgagtctt aaaaaaacct agattactct cttgatacag
     7501 tggatttggt tttaaatcta atcttggcga atctatatgg cttcctataa tcttcatacc
     7561 tttttctata taatttttac ctattacaaa aagtgctact gccttctctt tatttataac
     7621 ataaatttta tcaccacaac ttatgcttcc tttttccata gcttcatcta ttgaaatata
     7681 gttattttct ttagccaatt ttataatttc ttttactgaa agtctttcag tctttgactt
     7741 acttaaaaac tccatataat tgctagaata ttgcataatt tgttcaatag tattttcttt
     7801 tctttcaaaa tcccaagcat tcttaaattc gtactttaag ttcatatttt cctcctacta
     7861 agttctaatt tttattgttt ttcatgtatt gctcatattc ttctggtgaa actactttga
     7921 cactatctag tcttgatcta aagtgggctc taaagttttc taaatattct ttccttaaaa
     7981 tttctctttc tttgatttca tcagcagaaa ggattccctc tttatttttc tttgctaatt
     8041 cattaatcct atctaatttc ttcttgtcaa acattttttc ctcctaaaaa acctctattt
     8101 atttaataaa ataatttatt gctttttata tctaacttgt ttttatattc acaaaaaaac
     8161 tcatctatat tatcacttat tatagatatt cccttttcta gttcttccat gcttggacga
     8221 gctatattta tcctaaagaa tctatcatcc actagattgt caaaaaaata agtccctgga
     8281 agcattgaca ctcctttgtt taacataaaa tttgtaaatg cttgagatgt atatcctctt
     8341 ggtaattcta aaaaaaagtt tattcctcca caagattttc taacttttaa tttaccactc
     8401 aatttgtcat taatcaagtt ttttgccaat ttatacttat cagtatatat cttctctata
     8461 tgactcaaat aattcttcca atcaaaatta ttcatatagt aatacattga tttttgaatt
     8521 aaacctggtg ttgatatatc tgatgaatat ttagcccata aaactttttt taacaactca
     8581 tttggcattt ctacaattcc tatcctaaga cctggcataa gtatttttga aaagcttttt
     8641 atatatacta ctctattttt atcatcataa cttctaattg ttctattgtc ctttgattca
     8701 aaaacaaaat cacttataaa atcatcttct attatataaa aatcatgttc ttctgccaat
     8761 tctatcaatt tctttttttt atatgttgag taagatattc cagttggatt ttgaaaatta
     8821 ggcataatgt atataagtct tggttttatt ttttccaact ttaattttaa aatacctata
     8881 tcaattccat catctaacat aggtatagat attatttttg cacctctact tttaaacact
     8941 tcaattgctc cattgtaaga aggttcttcc ataaaaacaa catctgaata acttataagt
     9001 cctttacaaa ctatatctat accttgttga gcacctgata ttatttgaat attttcctta
     9061 gtagttttta tatttccatc acttagatac tctaccattt tttctcttaa ttcttcagag
     9121 ccaagacctt catcatattc aaatattgaa ctaccatctt tagataatgc catatttaca
     9181 gcatttttaa atgaatcgat aggaaacata tcattagatg gattcccatt gtcaaaatga
     9241 attaaatctt ctctttgcac aataatctta tttttcctgt tatctatacc gcttttataa
     9301 gaatttaaac ttgatacaaa agtaccactc cctataattt tatatacata tccttcattt
     9361 tctaaaagct cgtatacctt aactatagta gtgttattta cttgtaaaaa atttgatagt
     9421 tttcttattg gaggcaattt ttcatgttct actaactctt tatttattat caattctttt
     9481 atatgattaa atatctgtat atatttagtt gattttttct catttaaatc tattctgtat
     9541 ttttccaaat ttatcaccgc tcattgtatt tatattttat tgatgctttt atgtatattt
     9601 gatattattt agtatgtata tataatacca aaatttttat aaaaagggga aatatttatg
     9661 ttttacgact atcacatgca ctcaagtttc tctacagacg gaaaatctac aatggaagaa
     9721 atggtaaaaa aatctattga actcggtttg gaggaaattt gtttcacaga ccatgttgac
     9781 tatgatgtat atgctgatga ttctttttca attgtctacg aagattattt taagagttta
     9841 gagactcttc aaagcaaata taaagataaa atatcaataa aaaaaggaat tgaatttgga
     9901 gttcaaactc aattaatgga tacatacaaa aaggaagcac atcaatatcc attggacttt
     9961 ataatatgtt ctatccatgc tatagataca atggacttat accttggtaa ttattttaaa
    10021 gataaaactc aacatgaagt ttatgaaaat tactatcttt atttatataa tattgttaag
    10081 aattataaag attactctgt cttaggtcat ttagatttga ttaaaaggta tgcaccttat
    10141 gacactattt tagatgatag actattttct gatataattg aagaaactct taaacaagct
    10201 atttatgatg gcaaaggtat cgagataaat acctcttgtt atagatataa tcttccagac
    10261 ctaaccccat ctaagtatat acttcaaatg tacaaagact tgggagggga aatcataacc
    10321 acaggttcag attcacatca tataagtcaa gttgcatgtg agtttgacta catatattca
    10381 ttactaaaaa atatgggatt taaatatgta tctaaattta ataaattgaa accagaattt
    10441 ataaaattat aaatttttac acctccttgt gaatatattt aaaagataag gaggtgattt
    10501 ttttgaaagt accttattta gtactatcaa cagttatttt atttatatcc aattttattg
    10561 taagaatatt tggtttttta tataaaatat tcttatcaag agcactaggt gaaacaggtt
    10621 taggtatcta tcatatgatt tttaactttt tgatgatttg cttagctgtt acaacaacag
    10681 gtatacctac tgcacttagt tgtctagttg caaagagaaa agctttaaac gatagacaca
    10741 atactaatgc tttatttata tcaactttat atatatcatt tttcgtagca ctaattatat
    10801 ctatagttgc atctttcaat agttcttttt tatcacttaa atttttaaaa gatgctaaat
    10861 taaatctatt tatactagct gtttgtcctg ctatagttat aataactctt tcaaacgtac
    10921 taagaggata ttactatggc ataaagaatg taaaaatccc tgctattgga caaatcattg
    10981 aacaaattgg taaaatatta tttgtttttt tacttgttat gtacataaat aataaatcta
    11041 tgaattgtta tatagctcta ttaggtatat cgattggtga gttgagtaat attatattta
    11101 tgcttatttg cttatggcga gattcatcat ttgacaatag gtatattata agcataaaag
    11161 atttttataa ttcttctatg gaaacattaa aaatgtctat tcccataact tgtaatagaa
    11221 tgtcaaacat acttttgcaa tctataagtt ctatgatgat accatcaaga ttagcattat
    11281 caggaatgac ttatcaacaa tctttaagta tgtatggtat tgtcagtggg atggtaatgc
    11341 cttttatatt tttacctttt actgttggtt cagcgcttat tgtaaattta ataccaacta
    11401 tttcacaaga aatggctcta agaaagcgta agagtgtaat taaaaaaatc aaatactcca
    11461 tacttcttac tttatttgta ggcatactat catcaatatt tttttatttc tttggaaaag
    11521 atttatgtat attagtattt aaaaatacac ttgcaggaga atatctaaaa gctatgtttt
    11581 tagttccact atttatgtcc ctaaatcaaa ctctatctgg cattttacat tcaataagaa
    11641 aagaattagc ttcaagtata aatactatta ctggcatgtt aattcaacta atagctttat
    11701 atgtatttct tccaattcca ggacttaata tttatgcata catatacaca atgacgatag
    11761 tatcaatctt tacttgtcta ttacatacta tagtgctttt taaatcacta aaatctatac
    11821 gctagttata aaaacgtgaa ggctaccaat gtaaattata cactttggta gccttcctta
    11881 gatgattttt atttataatt taaactgtct atatatctac ctatctatct gtggcaactt
    11941 ggctttccac ttccatgatt aggtccacat tgcgaaaaat cacatacttt agagaaagta
    12001 tcaacaagtc ttggttggat tggatttggt gatgctaaaa ctactatttg ttcacttatt
    12061 aatgtgctaa ctgtttcttg taagcaaagt actaaatcta tatcatttgg tataattaat
    12121 tcatagaaag gttcacaaca ttcgttgcat tctaatttta atatagattt tcctatacaa
    12181 tctacagtta agttagtttg atattcttgt cttaaagtaa cagctcttcc gtcagctggc
    12241 aagcatattg gtgctgaaag tgtgttaaaa gtaaattcta cataatcaac tcttctctta
    12301 catccacctc ctgctctaac tgctgggaaa gctaatgcaa cgaactctgt acatccacat
    12361 ctacctctta gctctagtac taaattacga actgctacag ttaatcctct ttgtttataa
    12421 gctactgatt tgccttttcc ttgtctacag cactcagagt ttctttctcc acaaactgca
    12481 aattcaaaag ttgtttcaca gtttcttcct actatatctc ctaatgggtc taaatcgaaa
    12541 tcttctaaag ttgtcattcc tgtgtctata acgattccat cattacttaa gcatattttt
    12601 tctatagtta cacttgcttg acctgcactt ggaactgaac caaatacttc tactacttct
    12661 gtttcaaaag ttaatggctc tccatttggt cctgttgcat ctgtaaatgt ttggaattgc
    12721 atagtatcaa atattctatt agcctctatt gcaaatggca ctgcatttga tacagagaag
    12781 tttcttggag atataggatt acagcattct ggtccacatt tgttttcaaa acattcatct
    12841 gaatccattt cacatggttc acaatcacat ttacaattgt catggcatcc acaattgtca
    12901 tcacatggat taggtttgca tggattgcat gggttaggtt tacatggatt acatgggttg
    12961 catggattgc aatcatcatg gcactcacac ttattatcag tattacatcc attatgatgg
    13021 tgtgattttt taaaacctct catgtcttct gaatttattt catctgtata cacttcttct
    13081 tcattcattg tagacattgg ctgattcatc attcttcttt tatttttttt ataatcttgc
    13141 atttttcatt gccctccctg taagcgattc ttattaagtc tttggctttt tgaagcctaa
    13201 ttaatactat gcttttataa tcttaattgt tacttgcttt ttgaatttat caataattag
    13261 gcgtatttag tagaaaaatg catattaata aaaaaagtac tactatttga aatagtagca
    13321 ctttttttgt cccgaaacac cggtggctaa gtaaattcac accctaggca ctcccaggtg
    13381 ggtgacttgc cagtaacctt taacgtccaa actaactagg catgttataa tttaccagac
    13441 acggtctccc gtatttcatt tgtaggttga atttaaaaaa gccttatcgt atgtttcagg
    13501 atttcatatt attattatat aataaatttt gaatttttta aagtggtttt atatagtaat
    13561 tgagataatc ttattctatc attacttttt cttccttttt tctttatgta tttagttaat
    13621 tatcgttttt tcttagctct agttttagta tttttttcat tataattgta ttcggattct
    13681 tgctcattaa tgttgtatag ttcctcatcg tatactatat cttcatcatt ttctatattt
    13741 tcatagcctg tgttcttatc ttctactaat tcatcttcat tatcctccat ttcaccttca
    13801 tctgttaact catcatcatc caattctttg tcttcacaat ctaattcttc gtcttcataa
    13861 tttaactcat cattattgtc ttcatcatca ttattactat catcacctct taaaagactt
    13921 cctaacaatt tgagattatt catactacca agattgttta tatttgccaa agagctcaaa
    13981 ctaaatccac cttcaccaaa gtcatctggt aaaaataatt ctgcaaataa atctatcttc
    14041 tttttcattc ctatagcttt ttcaactgaa ttttttcttt tttctgggaa tacatctata
    14101 atttccttta tcatcatatt ctttttatca tcactatcca tttttctgaa aaaatccgtt
    14161 tcatcttctg tatctaccat atctatatta tttaattttt ttattcctct aactaaatct
    14221 aaaacacttt ctatttttat tagtattttt ctttcatctc ttgacatgta ttttttagtt
    14281 cttgttatta tttccattcc catttctaaa tcttcttcac ttaaatccat gagccttaaa
    14341 cctcttttta tatcatttgc atcaaacctt aaattgccat gtgtagactg tgaaagttta
    14401 tcatttgcat tttttttgtt ttttctaact ctattatttc cttttgattt atttttatca
    14461 tcaaatatag agatattacc attactcaat gcaatcactc caatcaaaaa tagtaagtta
    14521 ttcaagacaa ttccccctta tattatataa ttgccctata ttaaagtatg tttttcatat
    14581 tttaatgttc catttttaaa gctcagtgca tatatattat ctataagaat ttttatttat
    14641 attatatatc actcacaatt caccacttca atattatttc tatatataaa tagtatgaat
    14701 ataattcaat atatatttat agaaaggggt ttttttatga aaaaattaga tacagagtca
    14761 ttagaaaaaa tggctaaaca aaaaaatatt gacaaggata aaatagaaaa gatggctgat
    14821 agttacaaag gaaaatcaga aaatgaactt atggaggaac ttataaaaat aggtaagaat
    14881 ctagatggca gagatgaagt agtatcaaaa ttcaaagcat ttttagatga aaatcaacgc
    14941 aaaaaactgg ataatataat ggaaaaaatc tcagatgcag aaaaccaaag agatactaaa
    15001 ccagctaaaa ctaagaaggc taaacctact aaaggtaagt caaattcacc tgcaccaaaa
    15061 aatacaccag gtagtcaaca aaaaaaatct aaaagtttat ttaagaaaac taaaaagtct
    15121 aatcctcatg aatagataaa aataaactat ttaagcaatt agataattat ttttagttaa
    15181 tctattatta aatttgatat tattgacata aaaaatcagg tagtgcctaa ggcactacct
    15241 gattgatttt aatagtttta tttttttctt tctgtaacac tttctctatc aacaattcta
    15301 taaggtaact ctattttctt attttcaatt aattccttat ttattaattt tataaccatt
    15361 cttattgcta ctgctcccat atcgtataga ggttgatata ctgtagtaag tttaggtcta
    15421 tacattctag ctatcttaac atcattaaat cctgcaactg atatgtcttc tggaacctta
    15481 tatccagcat cacatatagc atttatagca cctatggcag cctcatcacc tgttacaaaa
    15541 gccgcatgag gtattattcc atcatctaat agttctttca tactattgta tccactctca
    15601 taatcagttc caccatactt aatcaaactc ttgtctaatt ctatattgtt atttgaaagt
    15661 gctttctcat aaccagcaag tctttccatt tctaaaacag tatcatcttt actagtcatt
    15721 ataaaagcta tcttttcatg acctttcttt ataagatgct ctgtcatatc aaaagtagct
    15781 tcttcgttgc tagtacttac tgtatatata tcataatttc tagcagtttt acttatatat
    15841 gtcgctggta ttccacaatt ttgtatatag ttgatatgtt cttgttcaac tatccatgaa
    15901 atcataacta taccttccac ttgttttgct ctcaatagat ttatactctt aagttcttgt
    15961 tccttatcag agtatgtatt cgctaaaaga atatcatagt catacatttt agcaacctct
    16021 tctatcccat ttaacacctc attaacaaaa gaatctgaaa cttctggaac tattacccct
    16081 attaattgac tcttctttgt tactaagctt ctagcaagtg gatttggtat atatccagtc
    16141 tcttttataa cctctaaaac tttttgtttg acttcatcag ttacaggttt tgaatcattt
    16201 ataactctag atacagtaga tattgacact cctgcttgtt tagcaacatc ttttatcgtt
    16261 atattgcctt tcatcttcat cctccttatt ttactaaatt tatctaaaac tgaaccaaat
    16321 ttttgaaggt tcctatttta actacattta tataagtttt tattttacca taaaagcaag
    16381 tacatttaaa tacattatat tttatattat accctatatt caacaaattt aataatattc
    16441 attcttaatt taaatcatat taaaaaataa aataaaaaaa tgctggtata aaataccagc
    16501 atttttttat tctaatgatt taagtattag cagccgcaac ctacttcacc atcaaagaat
    16561 ccaccacatg aacaagttat tagcaataat attaagaaag gtatccatga cattatgtca
    16621 atgtctctcc agcaatcttc aaaagctaag aataggaaga atagtactat tatccaccat
    16681 cctcctccac caaagcatcc ttcttctcca aaaaatctat ctaacataac aaagccctcc
    16741 tttttttaat aactgtgttc ttattctaag catccaccac agcagcaaag tattaataaa
    16801 actattagga atggtatcca tgccattatg tcaaattctg cccagctatc tccaaaagct
    16861 aagaatagga agaatagtac tattatccac catcctcctc caccaaaaca tccttcttct
    16921 ccaaagaatc tatctaacat tatacgttac ctcctgttga tattttgttg agcttttcgc
    16981 tcctaacata tactatgcat ttggtttcca ttttgctaat gtatttttac tattttttta
    17041 aattttttaa tttgaactaa aaaaggtaaa accataactt gtataagtta ctggttttac
    17101 ctatttaata atcaatattt tttagcaaca acaaccatca tcgaagttaa ataataacaa
    17161 tactattaat ataacccata tccatatatt gtcatcgcat aataagtctt ctaaaatgtc
    17221 tgtgcataat agtaagaata ctataactat tattatcaac attttattcc caaaaaatcc
    17281 ttcgcatcct ccaaagaaac gttccatatt gtcttctaat tttgtcataa ctaatcctcc
    17341 ttgaatcatt aagagactaa gttttgtctc tttaattaaa tatatgtagt aatagacaga
    17401 taagttactt ctaaaaagtt tttattgatt agtttattta tttctttttc accaagttta
    17461 ttgtatctat caacttcatc cagataatct tttttctcct ctgatatagt atagattaaa
    17521 ctttctattg attttatttt gtactcctta tatctttcta tcaagaagga tgtttttgaa
    17581 ttttctattc ctttctttac atgcattaac cttgatatgt aatcttcttt ttcattagat
    17641 acataactct ccttttcagc tacatcttca aggattaaat tggtctccat tacataatcc
    17701 tctatacgtt gcatatctaa agttattgaa ttataataaa aatttactgc tataagtaaa
    17761 aacattccta ctgaagttag taatagtcct acatatttca tagcatttcc tcctaagtta
    17821 tatttgttat caataaagtt tattcatcaa ataatacttt attactacat ttataaaatt
    17881 ttattatttt ttatagattc catattgaaa aattcttgat attatattaa actaacatta
    17941 aaattaatta aaactgcttt aggaggctta aaatgtttga gaaaataaaa gaaataatag
    18001 cagaacaatt aggggtagac aatttagatg agataactat ggaagcatct ttaatggacg
    18061 acttagaagc tgattcatta gatgctgttg aaattataat ggcccttgaa gatgaatttg
    18121 gaatagaaat accagacgag gaagctgaaa actttaaatg tattggtgat atatgtaaat
    18181 atatcgaaga aaacaaatag tatcgttttg tctacaaata taaatagtct gtgtaaactt
    18241 ctacataata aattatatta gagttcgcac agactagatt acatttattt acaatatata
    18301 aaatacacgc tcttatattt aatttatata ctaagtatat aaattacttt tcttcataaa
    18361 acgtaacatt ctttattatt atatctatag ttccatcttg attttgtttt acagtatact
    18421 tcattgggtc ttcaaaatca gttagattcc cttttatgtc aaaaccatta tccgttttta
    18481 tacttctttt tttaagcttt ttctcaaccc attttttatc tatactaaaa ctttcgtcaa
    18541 gacctttttc ttccatatgc tctttaaagc tatcctttaa ctcatcatct ttaattgaat
    18601 tatcaacaaa gtcatttata tcaacttcat gtttttcctt cagtgtataa tttaatatac
    18661 ttcttacatc ttcagcttgc tttatatcat tactaagagc attggttatc caattttcag
    18721 ctgtattttt aaataccttg gtcttgtact tatcatcatc tattttttta gcatttaaaa
    18781 attctgttac aaacttagat tctgaccctt ctttttcagc atccttatct aaaagcctta
    18841 gatgaaactc atcatttata ccacttagac taatcaaagc tccttgcttt tgtcttaaag
    18901 tctctgggat accaatttca tttgaaacca tttgaatatt aaatttatca tccacaaatt
    18961 caattgaatg agtgtacaac tttttataat ctaatttcag tattgctaca ctcttttcat
    19021 ctttaatagt gtataagcaa attgccaaat cacaagattc tagtgcagca ttaattttca
    19081 taacatcaaa caagtaagat gcaatttctt tagaattttt caaaaaagta ctttcatcat
    19141 atattatttg ttcacaacag tttttaatta aattgtcatt ataatcttta aaaacacctt
    19201 ttcttaaatc ctcatctttt gcaattcttt ttatagcttt ctggaaaaaa ccatctactt
    19261 cttgattaac tttgccttca aagtcattta atattggaac atcactattt ttgtccaaaa
    19321 catgtattat aaatttatgt attatcatat atatcacccc attatcttaa tttcgatatt
    19381 aactctttca tatcctctgg tatatctgct ttaaatttca atttttcttt tgttcttggt
    19441 tgttcaaact ctagcttata tgcatgaagt gcttgcctat ttattagatc ttcatctaca
    19501 taaccataca actcatcacc tattattcca tgacctatat gagccatatg tactcttatt
    19561 tgatgtgttc taccagtttc taagcttact tctaatacag ttgcattttc tagtctttct
    19621 attactttat agtgagtaac agatgactgt cctctttcat ctattatcct ctttattgaa
    19681 tcttctgtag gtctataaat tggctcatct atagttccct cattttcttt tataattcca
    19741 tcaactactg ttatatactt tttttcaact ttattttcac tcattgctgt agacaaagta
    19801 tgatgtgcat aagcattttt tgctactata actaaccctg aagtattcat atctaaccta
    19861 tttacaaatc ttatttttac attttctttt tgattatcta tatagtaact aataccattt
    19921 gctattgttt tatcatagtg gctttttgtt gggtgaacta ccataaacgg aggtttattc
    19981 accataatta tatcaaaatc atcataaatt atctgtaaat ttaaatcttg aggttcaaaa
    20041 tttgcttttt cctcgtctat ttttacttct attaaatcac cactatacac ctttaaactc
    20101 ggttttttat atactccatt tactaaaaca ctcttttccc tcttcatttt tgataatgac
    20161 ctaactgaga aatttagctt gtccaataaa acttctttta aagtcatttc ttcttcattt
    20221 gtatacgata taagattata tctttgattc tcttttttaa acaaactttt acctactttc
    20281 ttttatatct tcctactttt ttatatcttc aaaatcatga tattatatat tttacactat
    20341 ttttgtttaa tagataataa ttatttttaa ctataaaaac ctgtaagaat aacaaatagt
    20401 tattcttaca ggttaaattc ataattaaat atttaatttg taaatattat aatctaaaac
    20461 tatctcttaa ctattaaagt agttcccatt cctccaccta tacaaagtgt agcaagacca
    20521 gttttagcat ctcttctctt catttcatat aaaagtgtag taagtattct tgctcctgag
    20581 catcctattg gatgtcctat agctattgct ccaccattaa cattaacttt gttcatatct
    20641 atatttaagt ctcttattac agctacagat tgggcagcaa atgcctcatt agcttcaact
    20701 aaatctatat cttcaatagt catattagca gcttctaaag cttttttagt tgctggaact
    20761 ggtccatatc ccattatttt agggtcaaca ccagctgttc cataagaaac tatagttgca
    20821 agaggctcta ttcctagttc ttcagctttt tctttagcca ttactactag catagcagca
    20881 ccatcattta ttcctgatgc attaccagca gtaactgttc catctttttt aaatgcaggt
    20941 cttaacttag caagtttctc cattgtagtg ccaggcttaa tatattcatc tttatctact
    21001 acagtgtcac cttttcttcc ttttataaca acaggaacta tttcttcatc aaattttcct
    21061 tcagcttgag ctttttcagc tttattttga cttgcaagag ctaattcatc ttgttcttct
    21121 ctagttatat tccattgctc tgctatgttt tcagcagtaa tacccatgtg atagttatta
    21181 aatatgtctg ataatccatc ttttatcatt gaatcaacaa aagcagcatc acccattctt
    21241 gcaccatatc tcgcacttgg tactaaataa ggagacatac tcatgttttc agctccacca
    21301 actaacatta tatcagcatc acctaatgct ataagttgag atgccattga aacagatctt
    21361 aatccagaac cacaaactat atttatagtc atagctggtt tttctactgg tattcctgct
    21421 cctaatgcta tttgtcttgc tatattttgt ccaagacctg ctgtaagtac tccccctaaa
    21481 agagattcat ctatcatatc tggagttatg ttagctcttt ttatagcttc tttagctgct
    21541 gttaccccta actctaccgc tgaaactgat ttaaatgctc ctccaaaact tcctactgct
    21601 gttctagctg cactggcaat tactacttct ctcatattca ttacccccat taaattagat
    21661 ttttcatata tccgaaattg ttttttaaac aattttattt aaacttttaa ttcccaaatt
    21721 cttatttatt ataatcatag aatcctatct tagtttttct tcctaattga ttagctctaa
    21781 ccattttagc taaaagtgga tgaggtctat atttagtatc tccaaactca gtatataaaa
    21841 cgttcattat agctaaaaca acatctaatc caattaaatc acctaatgct agtggtccca
    21901 ttggatggtt tgctcctaat ttcatagctt catctatttc ttctttactt gcaacaccat
    21961 ctgcatatat accaacagct tcatttatca taggtataag tattctattt actacaaatc
    22021 caggagattc agatacatct actggtactt tattgatact cttagataat tcaaatactg
    22081 tatcaaaagt aacttttgat gttaactgac cacttataac ttcaactaat ttcatcatag
    22141 gaactggatt aaagaaatgc attcctataa ctttatctgg tctcttagta gaagaagcta
    22201 tttctgttat agataatgat gaagtatttg ttgccaagat agtatcttct ttacataatt
    22261 catctagtaa cttgaaaaca tctttcttta tattcatgtc ttctacagat gcttctatta
    22321 ttaaatccat atcttttaaa tcttcatagt tagtagttga actaacatga cttaatattt
    22381 ctgcttttgt agcttcatcc atttttccct tagtaactaa cttagttaaa tttttatcta
    22441 ataaagctaa acatttatct atagcacctt gagttctact ctttaaacat acatcatgtc
    22501 cacaacttgc aaaagtttgt acaataccac ttcccatagt tccactacct attacagcta
    22561 atttcatagt tataacctcc tgttatttta gtatttatat tctgttaact agattaaaat
    22621 actatttaat ctagttaaca gcaaatatat ttttaattag atttttaccc ttttataaag
    22681 ttagcttctc tcttttcaac gaaagctgac attccttctt tttggtcttt agttgaaaaa
    22741 caaagaccaa ataaattaga ttctatatct attccagtat ttatatcagt ttgagcacca
    22801 agttgtattg cttctttaga gtatctaact gcaagctgag catttttagc tattatctta
    22861 gctaatttct caacttcttc tattaaaatg tctggctcaa cgactctatt tactagccct
    22921 attttttcag cttcatcagc ttttataact tgacctgtaa agattaattc ttttgctttt
    22981 gccattccaa ccaatcttgt aagcctttga gttcctccat atcctggagt tattccaaga
    23041 gttacttctg gctgaccaaa tttagcttta gcagatgcaa ttcttatatc acatgccatt
    23101 gcaagttcac atcctccacc taaagcaaat ccgtttacag cagctatcac tactttttta
    23161 ctattttcta tttctccaaa agcttttgct cctaagatac taaaatcttt agcagctaca
    23221 gcatctaaat ctttcatgta tgcaatatct gctccagcta caaatgcctt tccttcccct
    23281 gtcaatatta caacatcaat agtttcatca ttattaatat ctacaaatac ttcataaagt
    23341 tcttctaaag tctttgaatt tattgcatta agggctttag gtctattcat tttcactgta
    23401 catatatttc catctacttc aacagctaca ttctcataaa ctttaacatc acttgtactc
    23461 ataataccct ccccaagaaa ttagttagct aaaacttcac ctttttcttt tgcaacactt
    23521 aactgactga taagttctgg aagcacttta tgaacatctc caactatacc aacatcagca
    23581 tatttaaata ttggagcttc tggattttta tttatagcaa ctataaactc agcatcttcc
    23641 ataccagcta tatgttgtat tgctccagat ataccacatg ctatataaag gtctggtctt
    23701 acagttttac cagtttgacc aacttgtctt gctttatcta accaacctgc atctatagtg
    23761 gcacgagagc cagaaacttc tccacctata atttcagcta attcataaag tatgtctaag
    23821 ttttcttttc cacccattcc acgtccagca gaaactaata tcttagcatc ttctatttta
    23881 acttgttttt tagcttcttt tattacttgt acaacttgaa ctaatttatc agcatcatta
    23941 aattctacct tgaaacggtt aattacagct tctttagttt catcaggttc atttttcttc
    24001 ataacccctg gtctaactgt agacatttga ggtctgaaat ctttacaaac tattgttgcc
    24061 attatatttc caccaaaggc aggtcttgtc attaataata attttgtatc ttcagctact
    24121 gcaagacctg tacagtcagc agtaagacct gtatgtattc tagcagaaac tctaggcgct
    24181 aaatctctac ctattgaagt tgcaccaaat aatacaacta tagggtcagc tgcttttatt
    24241 gcttcataag ctgcttttgt atatggttca gttgtataca ctgctaaagc ttcatcatct
    24301 actactatta cctcatctgc accatagtgt gctaatgtat ctattaaacc ttctacctta
    24361 ctacctaaaa gtaatgcaga aacttttgta tcataatctt ttgctatttc tgtagccttt
    24421 cctagtaatt ctaaagaaac agtttgaatt acattttctc tttgttctat tactactaaa
    24481 acgttaccca ttctttatcc ccccttaaat tatatgatat acttctcttt taatttatct
    24541 atgataattc cagctgatgt tttcgcatct tcattgtata ttgtaccagc tggtttaact
    24601 gattttgtaa atgatttaaa tacactagtt ggagaacctt taagacctaa attagaaggg
    24661 tcaacttcta tatcttttac agtccatgtt tctactacat cattttcgaa agcatcatat
    24721 attcttccaa ctttcatgta tcttggtgtg ttcatatctt taagagttgt tataaggcat
    24781 ggcattttaa cttttaagtc atggcaacaa tcttcaaatt gtctttttac taatacatat
    24841 tcaccttcag tttttatttc ttcagcatat gttattgatg gaagatttaa atgttcagct
    24901 atttgaggtc caacttgtgc agtatctcca tctatcgcct gtcttccagc tattataata
    24961 tcaaaatcta tattttttaa tgctcctgct aatgctgatg aagttgccca agtatcagca
    25021 cctgcaaatg ctctatctgt taataatata cctctatctg cacccattgc taaagcttct
    25081 tttaaagcca tatctgcttg aggaggtccc attgttataa cagttacatg agcacccatt
    25141 tcttctttta attttatagc ttcttctaaa cctgctttat catcagggtt tattatactt
    25201 ggtactccat ctctaattaa agtacctgta ttaggatcta gtttaacttc tgttgtatct
    25261 ggaacttgtt ttatacaaac gactatattc ataaatcctt cctccatatc tattttaata
    25321 tcgacctatt gtgtatattt taatatttat ctattttaat aattttcctg aaataaccat
    25381 tctttgaact tcactagttc cttcatatat ttcagttatc ttagcatctc tcatcattct
    25441 ttctactgga tagtcacgag tgtatccata tcctccatga agttgtacag cttttgtagt
    25501 aacttccata gctgtttcag ctgcaaataa ttttgccatt gctgcttcta ctccataagg
    25561 ttttcctaag tctttattta tagctgcttg atatacaagg tgtctagccg cttgtacctt
    25621 aacttccata tcagctaatt ggaattgtgt attttggaat tttgataatg gtctaccaaa
    25681 ttgtactctt tcttttacat atttaacagt ttcatcaaga gcaccttgtg ctaaacctaa
    25741 agcttgtgca gctataccaa ttctaccacc atcaagagta gacattgcta tcttaaatcc
    25801 ttgaccttct tttccaagta aattttcttt aggtattctg caatcctcaa atattaattc
    25861 actcgtagct gaacctctta tacccatttt cttttcttta actccaaagc taaacccagg
    25921 agttcctttt tcaactataa atgctgatat tcctttgttc cccttagatt tatcagtcat
    25981 tgccattact acatatatgt caccagctat tgcgtttgtt ataaatattt ttgagccatt
    26041 aagtatgtat tcatccccgt ctaaaacagc agttgtttgt tggccagacg catctgtacc
    26101 agcattaggc tcagtaagac caaatgctcc taatttttct ccacttgcta gtggtcttaa
    26161 gaatttttgt ttttgttctt cattaccata ttgatatata ggccatgagc caagagatgt
    26221 atgagctgat aatataactc ctgtagtacc acaaactcta gacaattctt caactgccat
    26281 tatatatcct acagtgtctc caccttctcc accatattct tttggatatg gtatacccat
    26341 cattcctgct tttgccattt tttccactgt ttcataagga aatctttctt cttcatcaag
    26401 ttctgttgct aaaggtttaa cttcattttc agcgaagctt acatatagct ctttaagcat
    26461 ctgatatttt ttagaattta aatccataat agcctcctca gtattttata aatattttat
    26521 tttcatttat taattaaaat ctcggcaaca tctataataa ggtatttgaa tatacgtcga
    26581 gaaatttata accttaatca aactacgctc tatatttata tgtgattata ctaaccaatt
    26641 atgacattaa tttaatcata aattgttaat ttaaaatcaa ctatacttaa aaaaaatctc
    26701 gctttttgga attttgtgaa atttcaagtt agaataagat ttctttcaca ctggttacag
    26761 ataaaataat ttgtttacga tatttatatt agggtatatt aaacattaaa tattgtctgt
    26821 acatctgttt tttagccatg tacagaagat ttttatcgta taaaaattat tttaatagag
    26881 ctaaataatc gtatttttat ctgactattt tttattttta aatatcttac atctataata
    26941 gtatcactca aaggataatt tttcaataat ttctaattat ttttttaaca atatttatta
    27001 cattttttcc acttttttgt cattttttta ttgtttcgaa aaaaaatcag aattttttaa
    27061 ctttattttg gattattagt ttaaattaga ttttcctctt agatttataa atatttacac
    27121 aaaaaaacta cctctgtata gattgtatac agaggtagtt ttttactaat tcctactata
    27181 gtttactata tttttttacc aattcttaca aacatctacc catttttcac acttagaaaa
    27241 cttctccatt tcttcacatg taagttctat tgcagagtta ctactgccac atgcaggaaa
    27301 tactgtatca aatcttttca ttgaatcatc taaatagact tttatagaat tttttaaacc
    27361 aaatggacag actccaccaa tagcatgtcc agtaaactcc aagacttctt ctggtgtcaa
    27421 cattttagcc ttacaattaa attcagcctt atacttctta ttatcaatct tagcatcacc
    27481 agctgtcaca attaaaattg catcatctcc tattttaaat gagagtgtct tagctattct
    27541 tgctggaata accccagctg cttcagctgc aagttccaca gtagcactag attgttcaaa
    27601 ttctaatata ctgtcttcct tgccaaattg tttaaaatac tctcttacat tacttattga
    27661 cattaaatat ccctcctagt ctgaactttt ataaatttca tattattctt aattatatct
    27721 ataattgatt tatttttcaa attattccat gatattagca ttccatgtat cattattttt
    27781 tccaactact agataaagtc cttttgccat tggaatattg acaatatatt ctcctttata
    27841 ctctacactc ataccagatt cattaaagta cctataatca aaatttagtc cttttggaat
    27901 tacaaaatca acataacctt gattatttgg ttttattcca tatttcagag ttctttcagt
    27961 tatagaattt ttttcattaa ataaatctac atttacatat gcagaacact tattcattcc
    28021 ctttttattt tccacacaat tttcaaactt cattttagca ctgtttaatt tataactata
    28081 tttactatta ttgcttattt taaatcttac aatagtacca acatctctac ttctcctgct
    28141 atcaaaatca aaaacaattt cctctaaatg atttatttca taatctttga cacttaccat
    28201 atctctatat actaatttat ttatagctat gaatagtgta aaaatcccca aaataaaaaa
    28261 tgaaactttt ataaacttct tcatttttag tctccttata ttttgtgcta ttgtgctata
    28321 atattaatca aaattttaat aattaaactt attctttttt gaaatcttaa tagaaaaata
    28381 cattgatatt ataaaaatta ttattgttaa aaatgtcata ctatataaat ttatatactt
    28441 agtattagct atatcagtta cataatttga aagatatact cctccaactt tactataatt
    28501 aaaatgcttt acttgatata caatcatact aatcatcttc aaaagacttc catatacaaa
    28561 gtaaattaaa atacttacta taaaaccaca aactttcatt tttccatatc caaacttaaa
    28621 aattaaaggc agtaaaatcg tcaaaattgc taaaaatata tttacagaaa aaaatacatc
    28681 atttaaaacc atatttctaa agaacactag tgatgtcaat ttacttagta aggacacaat
    28741 tattgttaca gaaattatta atcctacacc taataaatat tttgagtaaa ctatatcttc
    28801 tatactaact ggcatactcc ttataaaaat ccttgaatca ttttcataat cacactcaaa
    28861 cgtatttata aatatcaaat aactaacaac aatacttact gtataatatg aaattgaatt
    28921 aaggaaaaaa taaaacacaa aaaatagcaa tatgtacttt aaattacgga taccatctga
    28981 actaatccct attattaaat cttttcttat taaattgaac atcatctcac ctcatttaca
    29041 taataataca ttagttcttc tatagtagga tttttgacct tatgcttatc aatttctatc
    29101 aataggcttt ttactttcaa gctatctcca actttaacaa gtgcctcatt ataatattta
    29161 tactctttca caccaactat gctttcttta attgcttcta actctgcttt atttgcccta
    29221 attatcttat attcttgttc tattaattct ttcttaacag taaaaatctg atttcctcta
    29281 tttataaaaa caagataatc agcaatttta attaaattat cagtattatg agtagaaatt
    29341 attacactac tacttccatt tttcacaaaa tcttgtaagt actgcattat ttcagttctt
    29401 acaattgggt ctatcccagc agttggttca tccaaaatca ataacttagc attgtgacta
    29461 agtgcacttg ataacataag cttttcagat tgacctttag ataaattttc aatatgcata
    29521 ttttcttcta tatcaaactt attaaggtat tcatcaaacc tttctctatc aaaattctta
    29581 taaaataaag aaactatttt tctaaattcc ttaaccttta aatgcggata aaattgtaaa
    29641 gaatcatata caaaaccaat attgttttta aagcttattg gagaattttc aatagtttca
    29701 ttacaaagtt caatttcacc ttcatctgca tcaataatcc ccattataat ttttattaaa
    29761 gtcgtttttc ccgaaccatt tggtcctata atcccaacaa tatccccttc ctttaactct
    29821 aagtttatat tatttaactt gaattttcct aatttttttg tgatattcct tatgctaaac
    29881 acatcttcac ctcttatgca tttttttata cccacctata catattttaa cacattcact
    29941 acaaaggtca tttataaatt tataaattaa gaattataaa actatgttat aatacaaagt
    30001 atgaagaggt gaatatatga aaagaattat aactataaat acaaaccaat taaataagtc
    30061 ccttgagact aaagaactct taactagaaa acttatcaat gctggctttg aagtgtattc
    30121 agatatttat ccagacacag agcttattat atcaattggt ggtgatggct cttttttaag
    30181 aacagttaga gatttcgatt ttcctgagat tcccataatg ggaataaata caggtcatct
    30241 ggggtttttt cctgatattt taccagataa gattgatagc tttattgaag cttatacaaa
    30301 aaaagattat attattcaag aaatgtcact tcttaatgcg gaagtatata caactactag
    30361 tggttctaat atgcttgctg taaatgaggt tgttataaga ggagacaagt ctaggactat
    30421 acacctaaat ttaagccttg ataataaaca tatacaaaat tttagtggag atggtatgat
    30481 tatttctact tccacaggtt caacagccta taactattct gctggaggta gtattgttga
    30541 tataaatctt gaacttatgc agattacacc tttacatccg ataaatacca atgcatatag
    30601 gtgctttaca tcaagtataa tatgttcaaa tgaatctgtt ataaagattg caccagaata
    30661 tagatttgaa gattctgtat tgattgtcgt tgatggagtt gagcacagat ttagacaaat
    30721 cgaaaatata aaagttagta tatctgatgc aaaaataaaa ttacttagaa tgtcaaacta
    30781 tgagttttgg catagagtat ctgaaaaatt tttatagact gtacttagga ggatttttaa
    30841 tatgaaaata ggaataatga gtgatactca tggtagctta ctttactttg aaaaagcgtt
    30901 aaatgtatta tctgattgtg atgttttatt acatggtgga gatgtcttat atcatggacc
    30961 tagaaatgat attccagaag gatataatcc taaaaaattt attgagacat taaataaatt
    31021 agaaaacatt gtgattgtaa aagggaactg tgatgcagat gttgaccaga tggttataga
    31081 acatcctatt cagagtcctt atgtcatgag ccaatttggt gaaattagaa ttatattgaa
    31141 tcatggttat atagaatcag aagaagaaat tattgacaaa gcaaagaaaa tgggtggtga
    31201 catattagtt ttaggacata ctcatgtaaa aaaactatac atggatgata atttaatagt
    31261 aataaatcca ggaagtactt ctatcccaaa agatggaagc cattctgtcg caattataga
    31321 tatcataaaa actgatgatg aggatgagct tgaacttgat ataaacttaa ttgacatcaa
    31381 tactggaaat ataataaata tcaatgatta gtaaattttt aataaaaata aaataagctt
    31441 taatttatta aattcataat aaagacaagt aaaccatttt atttctatct caattagaag
    31501 tttaagtaca ataccttaaa cttctaatta aatagaatct ggtttacttg ttttattata
    31561 tgctatattg aaatataact tagtttactt gtttctatta tatattatat tggagtataa
    31621 tttagtttac ttatttcatt atatattata ctgaaatata acttagttta cttatttcat
    31681 tatatattat actgaaatat aacttagttt acttatttta ttatatatta tactgaaata
    31741 taacttagtt tacttatttt attatatata ttaaagtgca acttggttta cttgctatta
    31801 ttatatatta attttgattt acacaatatt actgtaaggc taatgcttct gcatatggtt
    31861 tactattttt acctccacca acttgtacaa atttatcagc ctttactttt tttataaaac
    31921 ttttctgtgc actacttaaa cttccacttg caagtactac aggtgacttt gtttttgatg
    31981 ctaatactcc agcagcaagc ccatcaacta aatcagcttc tctaccactt ccatcttttg
    32041 caaaatacat attattaacc ttacttgatt ttccataaaa cttttctaaa actttcgcat
    32101 tagtatcttt tctatctgtc cctgctagtc tttctgagtt tactaactgt ccttcaagtt
    32161 ttttacttat actgtactcc ccacctacta tgtatgtctt agttgagttt tgtgtaataa
    32221 aattctttgc ctcacttctt atgctatcct tacctgtata tattatagct gtattatcac
    32281 ttgcagctgg gcttgatatt gaagttgcat ctgccagtcc attataccca ttaaccactg
    32341 ccacttttga gacacctaaa tcaccagtat catctagctg tctagtaaga agtaaagatg
    32401 tttcttctct atctgctcca ccgattctac tgactaatac ttccatatct tcaagagatt
    32461 cttttacact tgatgaaata gctccttcac ttccaattaa aataacttct gctggattaa
    32521 gcctttttat ttcctctgtt acattatatg gtatactatt tttatttgta agcagtattg
    32581 gtgcatccaa tttacttgcc aaaggagttg aagccaatgc atctggcaat gaatttgagt
    32641 taactagaaa caccctttct gaaccattat tccaaccact ttgagatatt tttatcgctg
    32701 tatcaaatct atcttcacca ataagttttt cctcctttgg agattttcta ccttgaagat
    32761 aattgttcat atctacctgt gcattttgat ttttactaat attgtctgca tatacacaac
    32821 ttggcaacat aatcccaagt gaaagtgcaa atgctattat ttttttagat ttaattttca
    32881 atacaattcc cccttttaaa tgttaatacc tattgatatt catacttttt attgataccc
    32941 taaactaaaa ataattatct tttataaaaa taattacaaa aatagctata ccattttaag
    33001 tacaacacaa gcttataatc agcttgactt ataaagaatg atatagctat tataacttta
    33061 aatgcttaat ttttaaatac tttttaacta aactctttca gcatattttt cagctattct
    33121 tacaattagt ttagtagctt tctccataga actaactggt atacactcat ttttcccatg
    33181 gaagtttaat ccaccagtaa atatatttgg acaaggtaat ccattaaaag ataatcttgc
    33241 tccatcagta ccacctctta caggaactaa acgtggtttt atacctaatt cctccatagc
    33301 ttctttagct atatcaacta taaacataac tggctcaatc ttttctttca tattgtaata
    33361 agagtctttt aaatccaatt ccactctatt atcgtatttc ttatttattt tttctatatt
    33421 ctctatcata atagattttc tattttcaaa tttttcttta caatggtctc taataatata
    33481 agccatactt acattctcga catttccacc tatagaattt aaatgccaaa atccttcata
    33541 tccttctgtt gtttctggtc tttcatctgc tgggaacatt tctgatattt cagcagctat
    33601 atgtatagca tttaccattt tatttttagc tgaacctgga tgaacatttc taccatgtat
    33661 agtaatagtt gcatttgcag cattaaaatt ttcacattca agttctccaa ctattcctcc
    33721 atctaaagta tatgcatatt ttgctccaaa tttttcaaca tcaaataaat cagcacctct
    33781 accaatttct tcatctggtg taaatcctat ttttatatct ccatgtttaa tttctggatg
    33841 atttattaga tactctattg cagtcactat ctcagctata ccagctttat catcagaccc
    33901 aagtagagtt gttccatcag tgactattaa atcgtcacct ttaaattctt ccaactctgg
    33961 agaatccttt acatacgtaa taacatttaa cgcttcattt aaaactatgt cttttccgtc
    34021 ataattttct attatttttg gtttaatatc ttttccacta acatcttcaa ttgtatctaa
    34081 atgtgatatg aatcctatag tatccacacc atcagtattt ccttttaaag tagccattat
    34141 ataactattt tcatctaaac tcacatcatc aacacccatt gtttttagct cttcaactat
    34201 atacttagct aaaactcttt gaccttctga agatggacag ttctcacact gagaattaga
    34261 tgttgtatca aatgatacat attttaaaaa tctttccact actttttgtt tcacgtatat
    34321 accctctttc ttaataagat taatattttt ttatttacct gtgaataaaa ttttattttt
    34381 aaaaaatcta tcaattatta taattaaaaa atatccacct tcttaagtat atcatgcata
    34441 cataccaaac ccaaacaaaa aattactcca attattcctt ttacttggat tccaataaaa
    34501 atcgctgcta gggtagctaa tggatttagt ccaacattta ctgatactag tttaggttca
    34561 agtatttctc taatcaaaga caaaacaaaa aatatcacag tcatacttat agctataaaa
    34621 taatttttta taagaaaata ataaacaatt actggaagat atattgttat tatacctagg
    34681 aatggaatta aatccattaa agctcctaca aaccctacta ttagaccgta tttcaatcca
    34741 aataaagcaa aacttcccca gattgcaaaa aatgttatag ccataagtat tgtataggcc
    34801 cttatatatc caacaagtga aagccctgcc tctttcttta cgttttttac cttctttcta
    34861 acatcaacag taaacatatt ataaaaacta ttttcaatct tatcaaggtc ttttgctata
    34921 aaatacgtag caataaacaa ggtaattata aatattataa tatatggaat agaagtagcc
    34981 aatccaagta tactagtaag aagatttttt gtaatttgca ttacttcacc actgaatttg
    35041 tttactaatt gttctacatc aaaattggct atttcttgaa atgatttcat aaagtcattt
    35101 attttattta aaaaatacat aatagtatta cttatatcct caggattagc agatatatta
    35161 tttaaaaatc ccattaattc tttcattgaa tttattacta ttattgtagt aactgtactg
    35221 actatagcca ctgcaagaaa acttagaaca agagtagaga tacctttatt tatatgaaac
    35281 ttattttcta acttttgtga tataggatta atcataagtg ctattatagc acctagaaaa
    35341 aatggagcta tgtatggaaa cgctttgtaa ataaaaataa ataacaatgt atatatacaa
    35401 aaaaagatag tgttgttttt taatttgtat aaaaaattat tttctagtat gctcatctta
    35461 aaaatctcct ttcttctaat ttatattttt attttgtcca tttcatacta gttttatttg
    35521 aatacaaaat aaaaagaagt gtataaatat aaaagatatc ttttatattt atacacttct
    35581 aataaattta agaacattat tacattatgt atatattctt atttttttaa ttctattttt
    35641 ttctatactt tctatacaaa atcttatatt atcaacttca attacttcat tttcttctgg
    35701 caatctgctt aggtgtccaa ttataaaacc tcctatggaa tcaaactcct cagattccaa
    35761 gtttacacca ataagttcat taacatcacc aattttagta cttccatcta caatatactc
    35821 atcttctttt ataacttgta tttcatcctc ttcttcatca tattcatcct ctatatctcc
    35881 aacaatgact tctactaaat cttctatagt taaaagtcca gatgttccac catactcatc
    35941 tacaactata gccatctgac ttttttcaag tttcatctct tcaagaagtt gtgttatctt
    36001 tttgaactca tacgtgaaaa aaggttctct catataattt ttaatatcaa atgactctat
    36061 ttcttcatca gataaaaata taatatcttt tatattaagt attcctacaa tatcatctat
    36121 agtttcttca tacacaggca ttctacttaa tttttcagtt ttaaatacct gtattatctc
    36181 atcataacta tcttccatat ctatagctac catatctatt ctttgtacca ttgcattttt
    36241 agcttgcata tctccaaatt caaaaacatt atttatgatt tctctctctt ccatttcaag
    36301 gacgccttct tcatgactta catttaccat agtttttagc tcttcttcag ttatgaatga
    36361 tttagctcct ttatttgtta taccaaataa tttaaatata atatttgtaa ttatattaaa
    36421 tatccatact attggtctta atataaatat aattgctttt ataggtttag atactaatag
    36481 agaaaccttt tctgaattat ttgctgctat tgtttttgga gtaatctcac caaatattaa
    36541 tactaatact gtcataacag ctgtagcaag tgccactcct ttttctccca ttaatcctat
    36601 aaacaaagat gttgatatgg atgttgctgc tatatttacg acgttatttc caaccaatat
    36661 agaacttaaa agcttatttg gattttctat taatgaactt actaacttag ctcctttaac
    36721 tccttcatct tgcatatatc tgattctgat tttactcaac gacattaagg ccgtttcaga
    36781 tgctgagaaa aatgcagacc ctataagtaa tactattaaa aaaataatct gaatcaaatt
    36841 attgggcgat tccaacactt accacactcc tacttacatg tttttatatt aatattaatt
    36901 ataaataact ttaatattag tttttattat atcacaatta catattattt ggaaatatta
    36961 gataatatat tcaattaaca tatattttct aactatattc aatttttact tttgaaccta
    37021 ttccagcctc actagatgaa actaatagct taacaggaac tctattttta agttcctcga
    37081 catgacttat tatacccaca cttagattat tactatgcaa tctttccaag gattctataa
    37141 caatttctaa aagttcacta tctaatgaac caaaaccttc atctaaaaag aaaaattcta
    37201 atggtgcact tccctttaat tgtatttgag atgaaagagc aagtgctaat gatagagatg
    37261 tcaagaatgt ctctccacca gatagagtat caatgcttct tctttctcct ccattaaagt
    37321 tatctctcat tacaaagttt agtgttgagt caatttcaag tgcatatctt ccttttgtta
    37381 ttccatccaa tcgttttgat gcttccaacg ctatatattt taattggttt gtagaaacat
    37441 attctacaaa tttatttcct tgtacacatt tatctaattc ttccaataag tccacattgt
    37501 gttcaactac cttaagttgt ttattaaaat catttatctt atctaaagag tcttttaatg
    37561 ttattaactg attttgatta gctccaatat ctttggatat atttcctatt tctactttca
    37621 aattataaat ttcatctttt aactgttcaa agtactcctt ctttatgctt cttccattta
    37681 atttttcttt tgatgatttt attttaaatg ataataactt ttgttcttct tcatgctcta
    37741 gtatttcttc aatcaatttt tttactgcat cagtatctaa taaagctctt tttactgcat
    37801 atatactttc aaatttattt tctgccaata gtttatttag tgttgatttt tggtctttat
    37861 attgttcctt agcagtttta agtctaccat ctatattgtg cttttcagca atgttttttt
    37921 catattctaa tctttgctct tccaattttt tcttacttga ttcttcttgt tctaatatct
    37981 tacatatatt ttcttcaaca ttatgtaaaa gatttttagc taaatcacct ttcgttatgc
    38041 taataacttc tttatactta ttatctctac tcaatttctt ttctacatat aattctctag
    38101 cctttattaa ttctatctct atttcatgta gtttactctc attttctctt attttaatat
    38161 ctagtgagtc tctatttttt aataaatttg aatgcccagt acttagtaat tctaattctt
    38221 tttcattctc ccttatttct tttacttttg acaatagatt agagacttta gtaatcgtct
    38281 ttaatcctag gtattcctgt ttaagttttt tacatttatt ttctaaacct tctatttcta
    38341 tgtttaaatc tcttgttaat ttcttataat tattcagact ctctcttatt tttaattctt
    38401 ctttttcaat tttatttttt tcttctttag ctaatgttac t
//
LOCUS       DAGQVA010000034        38389 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.034, whole genome shotgun sequence.
ACCESSION   DAGQVA010000034 DAGQVA010000000
VERSION     DAGQVA010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38389
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.034"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(22..684)
                     /locus_tag="MIV85_001918"
                     /pseudo
     CDS             complement(22..684)
                     /locus_tag="MIV85_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(844..1380)
                     /locus_tag="MIV85_001919"
     CDS             complement(844..1380)
                     /locus_tag="MIV85_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBY2961257.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEETKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1453..1866)
                     /locus_tag="MIV85_001920"
     CDS             complement(1453..1866)
                     /locus_tag="MIV85_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBY2961258.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2359..2997
                     /locus_tag="MIV85_001921"
     CDS             2359..2997
                     /locus_tag="MIV85_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBY2961259.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISS
                     MDGTINSMQDSITDMQVEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIK
                     SDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3605..3784)
                     /locus_tag="MIV85_001922"
     CDS             complement(3605..3784)
                     /locus_tag="MIV85_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBY2961260.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDKSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(4010..4543)
                     /locus_tag="MIV85_001923"
     CDS             complement(4010..4543)
                     /locus_tag="MIV85_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBY2961261.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQITVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(5841..6413)
                     /locus_tag="MIV85_001924"
     CDS             complement(5841..6413)
                     /locus_tag="MIV85_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBY2961262.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(6475..6738)
                     /locus_tag="MIV85_001925"
     CDS             complement(6475..6738)
                     /locus_tag="MIV85_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBY2961263.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6738..6959)
                     /locus_tag="MIV85_001926"
     CDS             complement(6738..6959)
                     /locus_tag="MIV85_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBY2961264.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            complement(7472..8008)
                     /locus_tag="MIV85_001927"
     CDS             complement(7472..8008)
                     /locus_tag="MIV85_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBY2961265.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(8026..9339)
                     /locus_tag="MIV85_001928"
     CDS             complement(8026..9339)
                     /locus_tag="MIV85_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBY2961266.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            9694..10134
                     /locus_tag="MIV85_001929"
     CDS             9694..10134
                     /locus_tag="MIV85_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBY2961267.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQIPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(10319..10507)
                     /locus_tag="MIV85_001930"
     CDS             complement(10319..10507)
                     /locus_tag="MIV85_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961268.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            11511..11906
                     /locus_tag="MIV85_001931"
     CDS             11511..11906
                     /locus_tag="MIV85_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961269.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            11949..14048
                     /locus_tag="MIV85_001932"
     CDS             11949..14048
                     /locus_tag="MIV85_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBY2961270.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEDSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(14273..19483)
                     /locus_tag="MIV85_001933"
     CDS             complement(14273..19483)
                     /locus_tag="MIV85_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBY2961271.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKEIM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNALYEEHKDWIISKREDSGSA
                     GAEGKDGRSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YTEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVNLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(19498..21993)
                     /locus_tag="MIV85_001934"
     CDS             complement(19498..21993)
                     /locus_tag="MIV85_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2961272.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(22630..22917)
                     /locus_tag="MIV85_001935"
     CDS             complement(22630..22917)
                     /locus_tag="MIV85_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961273.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(22937..23212)
                     /locus_tag="MIV85_001936"
     CDS             complement(22937..23212)
                     /locus_tag="MIV85_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961274.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(23849..24028)
                     /locus_tag="MIV85_001937"
     CDS             complement(23849..24028)
                     /locus_tag="MIV85_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961275.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGHAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(24313..25788)
                     /locus_tag="MIV85_001938"
     CDS             complement(24313..25788)
                     /locus_tag="MIV85_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2961276.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYITLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
     gene            26857..28035
                     /locus_tag="MIV85_001939"
     CDS             26857..28035
                     /locus_tag="MIV85_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2961277.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFRNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            28385..29266
                     /locus_tag="MIV85_001940"
     CDS             28385..29266
                     /locus_tag="MIV85_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2961278.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESIKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKISNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            29457..29624
                     /locus_tag="MIV85_001941"
                     /pseudo
     CDS             29457..29624
                     /locus_tag="MIV85_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(29884..32451)
                     /locus_tag="MIV85_001942"
     CDS             complement(29884..32451)
                     /locus_tag="MIV85_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBY2961279.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSNP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRAIKSGQMITVDGLAGTVTFDE"
     gene            complement(32454..33059)
                     /locus_tag="MIV85_001943"
     CDS             complement(32454..33059)
                     /locus_tag="MIV85_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2961280.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(33433..34893)
                     /locus_tag="MIV85_001944"
     CDS             complement(33433..34893)
                     /locus_tag="MIV85_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBY2961281.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            35247..35825
                     /locus_tag="MIV85_001945"
     CDS             35247..35825
                     /locus_tag="MIV85_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2961282.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKALKMLYRLYDKN
                     PFLYSPNNTDYITLLNKIPKEMLSQLEYSNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            35876..36109
                     /locus_tag="MIV85_001946"
     CDS             35876..36109
                     /locus_tag="MIV85_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961283.1"
                     /translation="MIELIQRLNDIIYKINDKLNIHTKLVDPSSELMPLYSMLSIIVS
                     IFLIILGIKVRKKFLIIIAIISIIINILIILDR"
     gene            36118..37368
                     /locus_tag="MIV85_001947"
     CDS             36118..37368
                     /locus_tag="MIV85_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2961284.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            37529..38098
                     /locus_tag="MIV85_001948"
     CDS             37529..38098
                     /locus_tag="MIV85_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBY2961285.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT        13124 a         6517 c         4619 g        14129 t
ORIGIN      
        1 agtgtgcgta gctatttttt aatcaaactg gaatacagac tccattccta ggaaattggc
       61 tgaaatatag tctgctgtca aagatgctgt catcacagaa attaaaacag atactgaaaa
      121 gtttttatgg acttcttcaa gtgaaaacat aacacctgct agtggtgcat gaaaggctgc
      181 tgataatcca gcacttgccc cacaggttaa caggaatttt tcctctgtct tccctcggtc
      241 aagagctcta gaaatacctt tacctgccat agcaccaagc tgaatggaag gaccttccct
      301 tcccaaagca agaccaccca taagtgataa gaatcctcca ataaattttg ttggcaacac
      361 tcgccaccat acttgtttta ttttccctgt catttccccc tcaagctgag ggataccact
      421 tccagaaatc attggctccc agtccaccaa ctttgataca atccacgcaa gtactgcaag
      481 tactgcaaac caagctatta tttttattgt agaaccttct acaaatttta aaatttggct
      541 aagccaagta ccagcctgcc ctaaaagtat cctgtataaa agcacaatca aaccagccac
      601 agccccaacc ataagtcctt caccaatcaa aattacctga aagtgctctg cccgtttgat
      661 aatatgagat gtatcctttt tcatactgtt cctccttcat ccaataattc tacacaatct
      721 gaatctccaa tgactaaagt catgagtgtg tacagatatt ttttaatcaa caaaaataga
      781 tttttattta ctaaatataa gaaaataatt gctcaatttc tcaataaatg taaatttatt
      841 cttttaggta tttattctcc acagtcgtgc ttcttccagc aaaatattta ttagttcttg
      901 ctttctctgt gtatagattt tacgattgtc ctcaaactgt aatgccaatt tttgtttatg
      961 actatcatag agttttgctt tgtctgtaaa agtatttaga taatctcgaa aattgatata
     1021 attattccat gcaacactat tccattcaac aacatgaata tggtgagtac gagtattttt
     1081 ctcaaaatct cccatagcaa aaagtaattg ttttggtaca tcctgacctc gaaaaacgat
     1141 tccacattgc tctaaccttt cgaggtataa tttagtttcc tctaaagaag caacacctac
     1201 aacaatatca ataataggct ttgcgctaat actgggaata gaagtgcttc caatgtgttg
     1261 aatatcaatg gcagtcttat cccatatact tttcaataat ataatgacat cttttgcact
     1321 tttatcccat atcatctgat gttccaataa tttaaccata ccacatttta aacctatcac
     1381 tatataccac ctcaatataa tccaccttta tatatattac aattttttct atcttgataa
     1441 acagtgattt agctatttca ctttttcttg acactcgcta cattccctat catgaataga
     1501 tataattcct ccacatttag aacaagtata tctctccttc tgcttttgca taaacttctc
     1561 taaaccgtac tgctgaacaa atttactatt ttccataagg cttgcttgat atctcttgtt
     1621 ataacttttt tcaagatttt ttatgagttt acaaggaaaa ttgaaacatt caaaacaata
     1681 aaacaaccct ttttgacaga cacaatcctt tattttacac ttacggcagt gttctggctt
     1741 tcctgtatcg ccattcaaac aaccagcaca tggctttttg tgataacaat gcttatagca
     1801 aaccatacaa ttcattccac aaggagcaaa cataatcgta tcaatactct cttttggcat
     1861 tttcataaca ttttactcct ttcaaaaatc caatttgtcg aattgttata tattcatatt
     1921 gtaacataaa aaatagctaa aaaattcatg cactttcatt gccaataaat tttcaaggaa
     1981 atatgaaagt ttaaaactaa gaataaaaag agataaaaag gaagctacta atcaaaatat
     2041 tcaaatacaa gtaatcaata taaataactt aaggtatatt taaaagtata tgatattacc
     2101 agcagtttta aatacaaata taaccacaca tgcctcaaaa acacttatta cagtatctta
     2161 gaaacttaga caatacataa gattcattaa taaaaaagtt ctcaatatag tcattaataa
     2221 aaacgttctc aatatagata tatttaacca tgttttgaat agcagataat tatatgatta
     2281 aaaattaaat atgacatagc gtttgtggaa tataacacct aaattatgtt ataataataa
     2341 aacaggagtg tgatagtgat ggatgaaaaa atattagagt tattacagga aatgcaaggt
     2401 aatattagta atatgcaagg tagtatcagt ggtatcgaag gcactattag cgatatgcaa
     2461 agcaatatca atggtatcga aggcactatt agcgatatgc aaagcaatat caatggtatc
     2521 gaaggcacta ttagtagtat gcaaggcaat atcaatggta tcgaaaacac tattagtggt
     2581 atgcaaggca ctattggcga tatgcaaggt agtatcagtg gtatgaatgg cactattagc
     2641 gatatgcaag gcagtatcag tagtatggat ggcactatta atagtatgca agacagtatt
     2701 actgatatgc aagttgaaat taaagaagtc aatagtaggt tagacaatat ggaacctgat
     2761 attaaagact taaaaactgg acaagttgaa actagtagta gacttgatac tattcagagt
     2821 gatgttacag aaattaagtc agatgtaaaa attaacagaa atacattaga tacagtgatt
     2881 aaacatacct cttcattagt aaaagataca tcagatatta aaaatgattt aaataatata
     2941 gagatagtca catctaagaa ttcgaatgat attgctaaat taaaatcagt taaataatat
     3001 actatagtaa aaaatacctg aaaatttcac atacttcttt aaagttatac caaattttat
     3061 acagaaatac tgattatccg acaacacact ttacttataa ataatttatt aaaaaaatac
     3121 tcattttatc ctaaaattaa cacgactaaa tgagtcttga tataataata aaaaataagg
     3181 gagattggac actaaaaagt tgtgtatctc ccttatattc tataatatag ttatataatt
     3241 tttcagccta aaataaaagt ccatctttga ttaaaacaca tccccttatc acttataaaa
     3301 ggataaaatc ttgttttcat ttttccattt atatcttctt gcttaagagt aataattttt
     3361 tcttttgata ctttaagtgt ttggttaaat ttaaccaatc gactaagttt tgttcaacat
     3421 ctatttttca tattttccaa tacttaatct attttttata aataattctt tcatttctaa
     3481 ctcacttaca ttttttacat aaaacgaagc atataaattt caaccttatc ttgtatggtt
     3541 cttaatactt aatgagtagc ttaagtatca aacattataa attttcccct tacattcaac
     3601 actcttacca tttccaaaat atacaaaata tattttgaac atttgtacaa tgatgaaata
     3661 caatacatga aaatacaata tcataactct tgtctaaaaa tagaagttct tcaacataac
     3721 ctttcacaaa aaacatatta tctaagtatt ttttgtctgc tccttgtttt cctgtttgta
     3781 gcatataaat tactgcatct aaacatataa ctactcacac gaaaaaagaa aataaacttc
     3841 caaaatacaa gctctaaaaa ctacctctaa agttgtataa tgtttactag gaataaggtt
     3901 gtataacata tagtttaaat aatcattttt taaaattgca agttattgct ttcaaaatta
     3961 gatgtttgta tatcaaataa atgattaaga atttctaaat ttaatggctt tataatgcac
     4021 tccctttctt tgggataaaa taatgttgca cagatacttt ttctaaagat aacaatttta
     4081 tttttctatc aattccacca gcataccctg tcaaactccc atttgttcct acaacacgat
     4141 gacatggaac aataatagag attccattat gccctactgc accaccgatt gcttgtgctg
     4201 acattttaga tattcctttt tgttgagcaa ctttatatgc aatttctcca taagtgattg
     4261 ttttaccata tggtatttgt tgtaaaattt tccacactgt aatctgaaaa ggagtaccta
     4321 ccatatggag tgatggtgta aaattgggtt cttttcccga aaaataaata tctaaccatt
     4381 tctttgtctg ctcgaaaatt ggcaattctt tttcttgatg ttcttggtca agattataag
     4441 cataatactt ttgattctca aaccaaagac cagttaaccc aatattatct gatgctaaaa
     4501 gaatatttcc aattggacta tggtaatagc taatatattg catacaattc ctccttatat
     4561 tctgaaaact tcactcaaat cattagacac ctcttttcta tctaccatta tataaaaaca
     4621 tactaatata atttccttct aactacactt tcgttataat atctatcctc atatcatatt
     4681 agttttatat ttacctgcat ctgttcatcc ttttttccct ttccctttga tgaatataaa
     4741 attcatacat ttaagcttcc tactgtatta acttttatag aagtgtatat tataatttta
     4801 tcaccaaata gaccaaaaaa atatcgatat aacatcaagt aatatcataa tactttcaaa
     4861 tgggaaaagt aagaataggc tgtaaaaaag aaaagtattt ttatgttaga aatccagtaa
     4921 aatcgttagt agatagaata acagaaaacg aacaatttgc tatttatcat tttacacata
     4981 aatataattg acgcaataaa gtgttttcta ttctacaacg attaataagg ttagaaaaaa
     5041 gtaaaaatga actgtatatg tatgaagcat tagtttctgt ttctttcctt tggcttatta
     5101 tgataaaaaa tattgttttg ccaccaataa aacacaaaaa tataattaat atccatatgc
     5161 aaaaaatttt acgttatatt gaaaaatact attgttttac attatattga agggtactat
     5221 tgtgaaaact taattttgga gtactatcaa gcagtggtaa tatcaataaa tcagagtgct
     5281 ccagatgatt tgaactaagt ttaaatacta taccttataa atattttact gagttttgtt
     5341 tattaaaagc aactcaattt ctaaaaggca caaatgagct aataagtgac attactataa
     5401 aagttgtttt tcatcaaata atctatttta gtaaatgttt taaagaaaaa acgggatatt
     5461 ctccaaaagt gtacagaaat ataaaaaaag agatatgatt ttttatttct tttgattatc
     5521 caaagagtaa ataaaaaata ttgtaaaaaa cttactaaca acggcaatgc tttgaactat
     5581 ggtaatactt tgaacttttg attggacttt ttttgctaaa ataatatatt taaatagcaa
     5641 agtaatctgt ttaatcaata aaaaataaga gataaaagaa atcaactaaa acttttacct
     5701 cttattttga tagtttatca gagctaatat ttacactctt tttatttttg atacttcatt
     5761 aaaaatgatg cttactctcc attcactttt aattcttcat taaaaatgat gcttattctc
     5821 cattcacttt taattcttca ttaaaactga tgcttgcact ctgtaaactc ataaacatcc
     5881 attaatgctt caccaaatct ttgatagtga actacttccc tctcacccaa aaatctcaat
     5941 atatctttca aatcagggtc atcagttaaa tttattaatt gatagtacgt agccaatgct
     6001 ttttgttcag cagccatatc ctcatgtaaa tcagttaccg aatcgccaaa gacattaata
     6061 taacttgtag taaagtttac tccattagaa tctactggct gaagaccatg tccaaaatta
     6121 gcataattac taccaagtcc agcagcctta agctcttctg gagtacaatt gcctattaat
     6181 tgatataaca ctgaagaaat tatctcaaca tgagccattt cctctgtacc tatatcagtt
     6241 aaaagtgcac gagattttcc agttggcata gtatatcttt gttgaagata tctagttgca
     6301 gctgccaact caccattagg tcctcccaac tgagtcatga tatattttgc cattctaggg
     6361 tctgcttgtc ttatgttaac tggatgttcc agtgtttttt gataaatcca catattatct
     6421 tactcctcct taatatatat ttaataataa atctaatttt aaagtttaat aattttattt
     6481 ataaaatgat ttgtcccatg gccaaggttc agatatccat gaccaaggat attcacttga
     6541 ttcatatcca aaattagtta atgctccata tttagattca taatcacaca cagcttgtgt
     6601 aaatttatcg cagtatctgt tgtatgaatc aagagctttc ttatcccttg gattgttatc
     6661 taaatataaa tttaattcta tacaggcaaa ttgatattct gaaattctct ctaaaagttc
     6721 tcttctattt aatgacatta gtacatgtta cccccttttt tagctctaac tctattttta
     6781 ggatttgcat atagccaatc attatagtta tttgactcta ttaaatctaa ttcaggaaat
     6841 aaagtacctc tttttaatgc tgtttttgga ttgtatgtgt catcataaat ttgacgattg
     6901 atgtatggtc tagcaaattc acaacaatag tcttgtttat cctcttttaa atatcccatt
     6961 aattatcctc cttaattttt agaattttaa aatagcatta tttttaaaaa ttgtatactg
     7021 gttctatatt ataactggta gttttaatag gtctttaata agattaaatg attaaataag
     7081 tatctttttt tcttatttta cctctaaaat ttttctaatt aatctttcat aaatatctat
     7141 tttaaataaa taatatagag tttatacaat tttttatagc ttaattacta tttactatat
     7201 attattcatt tttaaataaa atgtgattat tttttattaa aaacaatata aatatacaat
     7261 ttaatactat tttttaaata agcttatatt aaaatacatt tagttatata attttattta
     7321 ttctaagagt ataattataa aaataaaaaa agaataggat aattttccta ctcttttttc
     7381 tgtacttaca tataatatta aaactcttta ttttttaata tatattttaa attttctttt
     7441 ttaataaatc tttttctttt aataaatcta tttaattttc ttcttctata tcagagccaa
     7501 agggaatcca tgcattacca aactctttat ctttaaataa ataagctaat ccagttattt
     7561 gcttcaatct aagaatttca tcaacttcca tacccaggtg ctttgatatc cattcatcag
     7621 attttccaat ttcacaaagt tcagttataa ttttactcat taaatccaca ttatgagaac
     7681 ctcttgcacg attgtgtcga atagtacttg ccattctttc atcaagagat ttatcaatta
     7741 ctgaaacagg aagaagtcca ttttctctat catatatatc ctcattttca agcattactc
     7801 tatatctatg aaaaccatct acaataatat acttatcctt ttcctcatta taataacaga
     7861 caattggcat tgtataccca tcttctttta tacttttata caacaactgc atttctggtg
     7921 gggctactgc atttggatta tagtcgttag attctatctt ttcgattggc actgcgatga
     7981 ttccatatac aggactttta tattccatag catcttaact cctatctaat gaattttttc
     8041 atatttcttc ttaatatatt ccgttctaat tctctgttct tttgtaggac caaatcccat
     8101 aaatctacac atatggtcat tttttaaaat acaataacac attcttttcc aacttggtat
     8161 atctttggta aatttaatat catccgtatc atcaggtata tcatccaaaa atatgactct
     8221 actcttttta tcttttgtat gatttgaaac tccatttaat tctattttat aaccttttct
     8281 caacaattca cgtataacta tttctgacaa accaccacct gtattctgcc aaaactcaat
     8341 agatgttgaa aattttttaa tatagctatt ccttatattt tcaggtaagg tatcaagcaa
     8401 aaaatatgtg aaacttttcc atgtgtgtcc atatggcaat ttaacactac gatatcccat
     8461 agcttttgtt ttgccataaa tagaagtaaa attaactcct tgtactctag caaccaattt
     8521 cacccataca tctgggtcca atattctgta taaatttaaa ctctcttttg ctgaatcatt
     8581 aaaaggtgat gccactctca tttttcttgg agctactcca gctttataga ataagtcata
     8641 aattttatta tagtcatagt caaatttata gtgtgctaac catatatctt ctatttccca
     8701 atcatatata ggagatgccg tccagacatt tttaaattcc ttagttatcc agcactttcc
     8761 tttatatcca tgctgtttat tcacaataga acaataacgt tgtagagatt ctgctgctcg
     8821 tgttcctaat aagcaaacaa cttttgcacc ttcatgtata tctctaatcc atctaccaaa
     8881 ttgttttgcc aaactttctt gtctcatttt atatttataa taagtaaaag gattattttt
     8941 ttgatttatt atgtattctt tgactggcat ttcccttacc cataactctt ctttctcatc
     9001 atcccatgga taccaataca tttcataatt tcctacagca gttcttgtag ccattggtaa
     9061 acacacccaa tatggttcaa tatcttcaat attatcttca aatacttttt caacatattc
     9121 agtagtcaaa ctatattgag cctcaaaatc ttgatgaaat actcctattt tggaacttat
     9181 attattcttt ctcttataat ccaaaactaa atttagcagt aaaccactat cttttcctcc
     9241 gctaaaagat acatagatat aatcaaattc attaaaaaga taagaaagtc tttcttgaaa
     9301 agcttcaaat acatcggatt ctaaatatct cttatccatt tgaattatcc cctttcaatt
     9361 agaagtttat aaaaccttac aatgcaatat tattatgctt ttttagcagt aatcagcata
     9421 aattatacat tatttaaata cacaaatcca actaactaca tataattata atgtaattat
     9481 acttttgtat tataaactat attttatcat tattttacat ttttttccaa tatatataaa
     9541 tatcatattt ttctattagc taaaactaat tactttatat ttctacgtat tagtataata
     9601 atacataaaa acttgaataa tgcataaaaa cttgacatac tgttgtcata attactttgc
     9661 tataattaaa agtaaaaatg gaggtaaatt ctaatgtatg aacgtatgct tgataaaagc
     9721 aataaaccct gtttgtctca aataatagaa tatataggta aagatggata tgcacgattg
     9781 tgtaagttgg aaacttactt gaaaactcaa tataatttat caagagaact tcgatttcct
     9841 tttggaaaca attatggttg gggttacaaa tatagccata aatcttttca tttattttat
     9901 gctttttttg aaaaaggtgc atttactgtt ctgattcaga taggtgacaa gcaaattcca
     9961 gcagtagaaa aaacgttggt agctttgaca ccaaaagcta aagaactctg ggtcactcgt
    10021 tatccttgtg gcaataatgg aggttggatt aagtatcgta ttttagaaga tgcagactta
    10081 cttgatatta ttcaatatat aagagcaaaa aaatctccac ctaaacaaaa ttaactttta
    10141 ttttttgtga tttaaatata gtgtatataa attccattct ttccatataa aaaaaataat
    10201 ataaaaaata tctattagta taacttattt agtatgtctt attctacttt ttacagataa
    10261 ttaaaaagtt ttatcataaa taaatcataa ctagacatcc tagtaaatca aaattaattt
    10321 attctttttt attagaattt ttgataacag tccctataca tatgccaatt atcattccaa
    10381 aaattagacc ataacacatt gtgataccta catttccttt agaaatacct atagcacaac
    10441 ctatagccat tccaagtatc atgcctataa acatacatat aataactaaa ttgttgtttt
    10501 tattcatagt tttctccatt caatatattt taaattgcct agctcgcctt cttagcttaa
    10561 aacaaagaaa tataaattaa ctttctttca ttctaatatc tgcttgtata aatgtcaaac
    10621 aacacatttc ttgtcataac ctcctctttt tgaagtaagt acaatctccc agacgcaata
    10681 atatcaattt cctaaaacca tttaagtaac ttttatattt acataatatt tacaatcata
    10741 aactatattg ttattcattt atacatcata aacactccct cctaatcatt attatactta
    10801 aaataatgtt catttataat aatatatcta acgcacttta attgaaaaaa ctaaaacttt
    10861 gcctttcatt cccatatata aataagtata ctttttgatg ctctattaca aatcaaccaa
    10921 attaattgat ataaattatc attttctgtt gaaaatacca ttcgcacatg ctatacttaa
    10981 ttgcataaat ggtaataaat gtcatatgat tttacaaatc tattaataac aattattact
    11041 tttactgtat tttaaatttt ttggactaaa tatcaagaac tttctaaaat acaaagtaca
    11101 aaaaatttat ataagttata aatttatatg aactagataa gctcaaacaa tatgttatgt
    11161 ataaactgtg tagtattcgg ttataaattt atataaatta tataagctag atatataaat
    11221 tgcttatata agctagataa gaattatttc aactatataa actacatata taaattacat
    11281 acataagcta gatatataaa ctagatatat aaactgcata tataagctat ataagaatta
    11341 tttcaaccat ataaactaca catgtaaaat tcatgtaaat ttactaatat aaatcaaata
    11401 aaattactaa actctctaaa ctaattttgt aaaacatact ctatttttaa catttgttac
    11461 cttatacata agtacaaaca aaatctaact aaatgaaagg ataatgtaaa atgaatattt
    11521 taaaaatgaa aaaaacaggg atatttttag gaggagtact ttttggtact gtaggtgtta
    11581 agatactttc aagtgattgt gttaaaaaaa cttgcactcg tgcaacagca ggagcattga
    11641 aagttaaaga ttctgttctt gaaacaacta cgaaaattca agaaaatgta gaagatattt
    11701 tagctgaagc aaaagaaatc aacgagcaag aagacttatc tacatctaag gtaaacgttg
    11761 tacaagatac tcttaaatgc gaacaagaag ttcttaaaac tgaaactata aaaactgtag
    11821 aagatactaa ttctaatagc attaaatgtg aagaaatcaa agataacgta attgaagaaa
    11881 aaaatagtac ttgtacaaca gaataaattt aatgattatt atgattaata atatcaggag
    11941 gaagtaaatt gaatttttat ataaaacacg aaataagagg tcgtatacgc tttgacttac
    12001 aacttggcaa attaaacaac aagcagtccg atactctctt atattattta acttctataa
    12061 atggtattac caaagcaaaa gtttacgata gaactggtga tgcagtcatt tattacactg
    12121 gtgaaagaga atacataata agagaaatca ctaaattcag ttttaacaat agcaaaatag
    12181 aaaacctagt tcctgaacat accagcaggg aattaaacaa ttattataga gacaaattag
    12241 caaataaact gctagtcaaa agtatctcca aaatattttt tccaaagtcc ttaagatttt
    12301 ttttaattgg acttcattct ataaaatatt ttaaaaaagg tctctcttcc ctgctaaata
    12361 aaaaaataga agtttctgtt ttagatgcca ctgctatagg tatttctatt tttagaaaag
    12421 atatcaatac ggccggttca gttatgtttc ttcttggtat cggtgaacta ttagaagaat
    12481 ggactagaaa aaaatctata gacgacttgg ctcaaagtat gtcactaaac attgaaaaag
    12541 tatggctaag aaaaggtgac actgaaatct taattccaat ttcagagata aaggaaggag
    12601 atttagtaag tgtaactatg ggaaatatga ttccattgga tggagttata gtatcaggag
    12661 aaacaatggt caatcaggca tcacttacag gtgaatccct tgcagttaac aaaaaagaag
    12721 actcttacat atatgctgga actgtaatag agcaaggcaa tattgttatg tgcgtcaagg
    12781 aaaaagctgg tactactaga ttccagaaaa tagtaactat gattgaggaa tctgaaaaac
    12841 taaaatcttc tgtagagagt aaatttgaac atctagcaga tacattagtt ccatacagct
    12901 ttttaggaag tatattaacc tatgcaatta ctagaaaccc tataaaatca ctctctatat
    12961 taatggtaga tttctcttgt gcattaaaac tctctatccc tatttcagta ctatcagcca
    13021 tgagagaatg taacaataac aacattactg taaaaggtgg aaaatttctt gaaggtgttg
    13081 catgtgcaga tactattgta tttgataaga caggcacatt aacaaaagct caaccaactg
    13141 tttcagatat aattacattc caaaattata ataaggagga tatgttaaga cttgcagctt
    13201 gcttagaaga acacttccca cactccatag caaatgcagt agtttatgaa gctgaaaaac
    13261 aagggcttag tcacaaagaa atgcatacag aagtagaata tattattgct catggcattt
    13321 caacaaaagt tgatgataaa aaggttgtaa taggtagcaa acattttgta tttgaagatg
    13381 agaagtgtac tatcccagac ggtgaggagg ataagtacaa taatctatca gatgagtatt
    13441 cacacctatt tatggcaata tcaggtaaat tatcagcagt tatttgcata aatgaccctt
    13501 tacgaaaaga agcaaaatat gtaatttcaa atttaagaga atgcggaata aaaaagattg
    13561 tgatgatgac tggagatagc gaaaaaacag ctaaatctat agcaagtaaa gttggtgttg
    13621 atgaatatta ttcagaagtc ttaccagaag acaaagccaa ttttgttaaa agtgaaaaac
    13681 tcaaaggtcg caaagtaatt atgattggtg atggaatcaa tgattctcct gctatttcag
    13741 aatcagatgt cggaattgca atgagtgaag gtgctgaaat agcaagagag atttcagata
    13801 ttaccatatc agcagataat ttgaataatt taatcgtttt aaagcagatt agtaataagc
    13861 ttatgaaaag agttgattta agttctaagt ttattatcgg ctttaattta ggtttgattt
    13921 tacttggtgt aggtggattt gttagaccaa gtacatctgc ctttttacac aacgcatcta
    13981 ctgtcggaat aagtttaaac agtatgacaa atttattgga aaacaccaat acttataact
    14041 accattaatc tccattacat aaaacatatg atataaaaaa tttataattc atcttttaaa
    14101 aagaatatgt cttaaaatta gcttttttct aatcaaaatt atataaagca tactttacaa
    14161 attttaaact caacttattt ctatttttta caaaaaagga gatgattcaa attttcattt
    14221 tgaaacatcc ccttttgtaa atttctttaa aatttatata ttaattatat tttcaaccaa
    14281 taattgtatt ttcaaccaat ctttcttcat agcattttaa atcattttgc tttagataat
    14341 taaattcaga ctctacataa ataccacagc ctaccaattc aattgtcaaa ttaggtatat
    14401 tttcctttag tatactagtc tgctcataaa taattctttc caataaatta acttgtaata
    14461 tagaaaaatg cttcataatc tccccatcac tatctatatc tttcttgatt tcataccaac
    14521 tctttgacaa aattcccttc aaatcaatat accctagact cctcaatata tctatactat
    14581 cgctccatgc atacttacta ggtttatcaa agtatgattc tagtttcttc ttctgctcat
    14641 ttgtaagtga atcataagaa agcttcctat taaaatgtgc cttcaaagaa atcttagcca
    14701 tagaatatgg acttctacca gagtttaatc ctgcattttt gaacttttca attcctttat
    14761 cttctactga agaccatatt gagtttattg aatctgaatc attgtattta atatcaagac
    14821 catgtgtaat atttatatag ttttgtggaa atacatattg ataatagaca tcttttttat
    14881 catcatatag agagaagtat ccactatcat ataaatgaat atgcaccttt acttttaaac
    14941 tatcctctaa aatatttcgt ctaaggttcg ggatatttgc atacatggtt acatatttta
    15001 tggcatcaaa gtttttattt aatggaactt caaaactaat ttcatctcct gtcaaaagct
    15061 ttttcacttc ttcttcatta caatcatata gagaatatgt attttcaaat cccacacgtg
    15121 atttcccatc taaactgcct gttaatgcta ccttcaaaat atggttatct gttttttgcc
    15181 attggtaagc atcttggtca agaaactctc taatctgtct attttgctct ttcgcctgat
    15241 ttataacctc gttttcatct tctgtaatcc ctacatggca tctatttaag atatttacta
    15301 tattgcttcc aaatgggaat gtccatagtt gaaaagctgc tgcctcaacc tgacacaagt
    15361 atctaacctg atttaattca atttgatgga taagtttttt ctgatattca ttcatctgat
    15421 taccactatc tgacatttga taaatcaatt ctcccattgc aagattatct tttttcttat
    15481 caatcttatc agtaatgata atttgagttt ccatcatatc ctgtactttt ttaaatatta
    15541 tagaaatctc ctctgaattt tccattttta agcttccaaa ctttgtgctt aattcagtta
    15601 aaacttcctt catctttaat ttacttatct cattttcaaa aatatcttga tttttaactg
    15661 tactatcaaa tttttctaca aatggtataa cagattcttt caaagtttta tctttaaatt
    15721 ccaccatttg agtattcaat tcatctaatt tcttaatatt attttcttta tctttaattg
    15781 cctctttaac tacctctatt ttactctcaa aactagattt tacattaaga caattattaa
    15841 caccactaat cgcagtattt ataagagaac aagcagaact tccaatactc aatgcatttt
    15901 taattttaga tgtcttttgc tgtctttcaa tagcttgttt acttttctct agtgcagcta
    15961 acttatcttt ttgctgttta ttattgtaat ttgcctccaa catacctatt tcttttttct
    16021 ggatttttgt gtaaatttcc gtatactcgc tttcacttaa cccctctttt gctctttgaa
    16081 tatcgtcagc tttgtctgca taattatcat catctataga cttaactata atctccttaa
    16141 tttggtcaaa tttagttctt ctttcttcat caacacctgc caaattataa gtcattttat
    16201 ctaaagcatt ttttctatct tcacttagct gttctccaag tacaaatctc ataccatcag
    16261 aatccaattt aaaatctgaa aaatcaacca tcctgttggt ccattggtat tcctcttctt
    16321 tagctgaaag attttccttc aaagattttg cactgtcaaa tgcccctaga caagcttgac
    16381 caacaccact aaatgcagtc agtaaactca atgcgctttg tattccagaa agaattaact
    16441 gtgttttcat ttgttcctca agttttgcct gtttcttttt tagttcctct atgtcttctt
    16501 gttcatcttc tttcatcttt ataatttctt gaatcaacag gttcattttt gcattaacag
    16561 aaagcatttt attctcaagt tcatttttta aaacctctat ttgttgattt ccagattcaa
    16621 tttgagttag gatactttcc ttatatgtat tgaaatatcc ttcttttaac tcatctttct
    16681 tcccttgttc caattctctt aaggtcttat ccagataatc tgtcaaagaa cgaatatctg
    16741 taacacgatt tcctccaatt tcactttctt caatcatctg cacataaaat gctgtcttct
    16801 gctcaagtgc aaataaaatc atactccatt cgctaaaatt ctgatttttt cctacaaaag
    16861 attctattct atcagactgc atcaatttat ttataaggta ttcatagatt tcctttgcct
    16921 ctttataaaa ttctttcttt gtattcatat catccagaga aagtactgct ttatttttct
    16981 tctcaaaact atagtacttc tgaagtattt ctctatttaa ttgcatctct attttctcaa
    17041 ctgcataaaa aatttcataa atatgtgaaa attctaaaat atcagcttct aaaattccta
    17101 ctgcacacaa cagtctaaga tttctataac ctttaattcc agaaaaacca aatctctcga
    17161 aaaattcata gaagaatgta tctattgaca aagaatactc ctgctttaac aattcctttt
    17221 cttttagtgc atctccagag cgaccatctt ttccctctgc tccggctgaa cctgaatctt
    17281 cacgtttgct aattatccag tccttatgtt cttcataaag agcatttaat ttctctccat
    17341 catctgctgc ttgcttctga tttaaagcat gattaaacac atatctatca aaataatagt
    17401 agtttctatc actattatcc attggaggag aggtacctat atatcttatt gtttcttcat
    17461 atatacctct aattccacca agacctcctg caccaccagc tcctccagag cctccttttc
    17521 ctgctaaacc atgatttcca tcttttttac ttatagcact ttttaataaa ggagcttttc
    17581 caaggagata aacctgtcca gacttgcttc caagacctgc atttccacca ttacctcctg
    17641 tgcctccagt tccaccttgt tttccttttt ctgcttttac cacatagtat tttgtacctt
    17701 taacattagc aaattctttt gactcttttt tagaacctat tttagcattt gccccagctt
    17761 ctccagttat ccctgtatct cctttttttc catcttgtcc atttccacca cgtccaccat
    17821 ctacgtaaag tttaagttct cctctttttt ctatttcttt aaaagataat atgatatcac
    17881 ctgaagtacc tgcattattg ccatttcttc cattcattcc gtcgtaaata gaactttctc
    17941 caaccaattt ttctgcatcc ttaccagata cgttgattga ataagtccct tctggtatat
    18001 gtaatttttc tgtaagtagt acaatattct tacctgagaa gacttctttc tccatattac
    18061 agtcaatttt caactcacaa tctccataca tatatataga tgacaaaata ttaagttgat
    18121 aaccagatat tattttagtc aaatccgata aattcacttt aggtatagga atatatatag
    18181 aaagtacatt ttctttctca tatgatttta tatatgtaca actttgaatc ttctctatcc
    18241 tatactctgc atcttcaagc tttttggctt cttcttccct atattcttct tctgctatcc
    18301 aatatttgat atcttttaat gtatcttcta aagtattttt tagcaatgat tttaacaact
    18361 cacttagacc aacaatatga gtctcactac agtaactatt taactctaaa agaagacgtg
    18421 tttcttctaa tatattcact ttctgtacgc catcaccata tgaaagttct tgtacaaact
    18481 ccataatctc tttcatatta ttagtcctac tacataaatc tgtatacatc ttatctaatt
    18541 gaatcttttt atcttttaga ctatttatag aagatagaat ggaaatagaa tcttccatac
    18601 cttttttaac actttctata taaggaacta aaagtttttc taggtcttta taggttacat
    18661 caacagcttt ttgtatttct attttacaag aagcagtaag catcaacccc aaatctgttt
    18721 tttcaaatgt ttcaggtaga tttttcattt catccaacaa cttttctggc tgtttatcta
    18781 gtggattaca taatttaata gatacaccat ctgataatgc tacatttaat aagtacacta
    18841 attccttaca accgtcgtaa tctttctctt gactatctag gtcttctttt gctttttcca
    18901 atatatttct tattttttct tctgttacat taccaattag tgttttaggt attttattga
    18961 taagaaagaa gaaattttct ttatactttg cataatcacc aagcatatct ttcaaatttt
    19021 tgcctgtttc tatcaataat gtatgtctag agtccagtag ggattgatag tctaaaataa
    19081 ctaccatccc ttttaccttt gaagatgtgg aaatagtttc ccttacaagc atagcaccag
    19141 caatcatata ctctgctcca cggttatcaa aaaaacctgg gcaatcacat aatgaaaaat
    19201 ctctatttgc aatatctaca acttctggac ataaagtctt agaatataca ccatttccaa
    19261 tttcgacagc tgaatctttt gcagttatat atatttgtcc agtctcttca tccgtttttt
    19321 cttccatcac acagcctttt aaataattta tacaagtact ctttccaacg cctgaagcac
    19381 ctaagaataa caaaattgac ttttctttta agtcatattt tctaagctcg tctcttcctt
    19441 cttccaaaag gtttacgatt tcactataaa gtttatttgc catacatcca tccctttcta
    19501 tatttcggaa caatagcctt gatatttttc tttaataaga ttctcttcta cctttgaaac
    19561 agctgttgat aacttagtgt ttggagcatt aaatcctcca ttgtctcctc tatctccata
    19621 ttcagcgtat tctcttgctg gtcctgtttt accttcattc cagcttccac cactaaattc
    19681 tatatgatat ttaattatac tatctaactt ataatcccaa cttgtaaaat atcctgtata
    19741 gtatacagtc ttatctatac cacttggaga aaatgaaagt gtattatatc cgtgatagcc
    19801 accacttcct ccatatccac ctaaacctgg tctaccattt ggacctgctt ctccatcttt
    19861 cactgttata tcacaatgat taattattct atttttttgt tcctctgaat ctgaaatgaa
    19921 gtaaatatta cctttcttac cagcatttcc acctcttcca gcatttccac cagctccacc
    19981 tttttcacct tttttgccac ttgtaccttt ttcaaaatac cctttaaaca tctgtccgtg
    20041 gaaataactt gtatatcctg catcagctcc attacttcca gaagctcctg tttcaccatt
    20101 ttccccatct attcctttag aaccatttcc tccatttgca atcagtgtta gacgataatt
    20161 tctaatttct tctttaatat ataagtaaat attacctgca tctctaccat cttcaccatt
    20221 tttcccatac atagaattat ctacaagttc tccgctcttt ccacttacat taatttttac
    20281 attactacct acatcaagat tgttagaagc aagaataata tttttctctg atgcaaagtt
    20341 cattccaagg ttatcatcca tataaatagt atctttagca aagaacataa atgtagaaac
    20401 attgtcatct acttttctat ttttgaaata ttccaataca ctgctaatta ctaagtttgg
    20461 aattaatgct cttatttcaa tacctttctt atcattaata ttaattgttt ttactataaa
    20521 tggatttaaa atgtatttac caataaattc tctaattatc tcattacctt cttctccata
    20581 tgcacttaat cttgttatac tgtcttctaa ctcttcattt tgtgtaactg taacatttgt
    20641 caaaattgaa ttaaaatcac ttacactata tacataatcc tttttatttg caacttccat
    20701 taatttttct ctatttggta atgtaaatac ctgtttttgc acttcataag aaactaaaac
    20761 tttttctaaa ttctttctta ttataatgaa gttttgttcc attatcttct tacttgcctt
    20821 ttctataata aattccatat gtacagaagg taataaaatt tccccagttc catgttctgt
    20881 atatttactt aaagcatcaa ttatatctaa gtttcctttt atcttatttt gtaatttcat
    20941 gcaactatct tgtaagaata atccactttg tttggctaat acgttgataa atctctctat
    21001 agtaagactt gttgtacttt ccaaccagtt tttaaatact tttacaacct catcatattt
    21061 tgctatttct tgaatcattg ttatacttcc aataatattg ataaaatctt ctgtatacgc
    21121 cttaacataa tcttctaggc tagatacgat attgttttga atttctttta tcaacgtatc
    21181 taaaactaat cttgcatctg cactaattgg atattggaat gctgatgtct tatctttaac
    21241 ttcatctaat tctagtactt gctttaataa gccttccctc tcatctgatg caagtggctt
    21301 acaaagatga atattttttc cattatcttt tagcaattct tcaaataacc aagctttttc
    21361 ctctatatta ctgtctaaat tttcgcataa ttgttcatat tttcttttta taacattata
    21421 tatttgtttt tctgttcttc ctaagaaact ttttgaaatg aaaaaagtta tactaccctt
    21481 aaaattttct ttatgaagac acatatttaa ctgttggaac aggtctagta cttttgtaag
    21541 tctagaatct aatatatctg cttctggtat caatacaatt actgcacata tagatgcaga
    21601 atttttaaat acttcaccta atgaaactgc tgcactaata tcatgggcta ctcccctatt
    21661 gtcgctaaaa cctgcagtat cacataattt tgcatccatt ccttctattg gttttctcat
    21721 atttacaatg ttcgggtata aagtttgaga aacagctcct gaaccaatct ctgccacagg
    21781 gtctaagcaa tcaatatatg atataccagt atcttcatct tctacttcca tcattacaca
    21841 tcctgcaaga tagttaattg cagtactttt gccacatcct gtcccaccaa gaattagaat
    21901 taaattttga ttttcagcct tatttattgc tacttttcct tcatttaata agagtgttat
    21961 ttcttctaaa agttgattgt tattttctgg catttatttt cccccttggt tatatatttt
    22021 atttaaataa agtttaatcc cttaagtaga ttgcaaagtt tttatactat atttaaattt
    22081 gttttttatt ttttattttt aataaatttg cattttcact aaatttgtat tttcactcaa
    22141 taattattct tctttgttta ttaaaataac tgtgttgtat aatataatct ttatcaacac
    22201 agttatttta tttaatgcgc ttattttatt gtattttatg taatacagtt gttttttata
    22261 ttatatgtcc attattttcc tgtggttatt acatatagat ttttaattat atttgtacca
    22321 ttaatttaaa cattcctata ctactgctta agttttacac ctataccagc ttgaatattt
    22381 tatttttatt tgcttaaata gttcaactat actggtttaa ataggttatc tttatttgct
    22441 taaatagttc aactatactg gtttaaatag gttatcttta tttgcttaaa taagttcaac
    22501 tatactggtt taaataggtt atctttattt gcttaaatta gttcaactat actggtttaa
    22561 atagttttcc tttagtttaa ataattcacc tatacctact tgaatagttc acttttattt
    22621 gcttaaattc tataccaata ctggcttaaa cattatacta ccatgattgt attgtctatc
    22681 ttcaactaca ataaaaacag gttctaaatc tttagtagat gttattttta attctaaaaa
    22741 aacattatca gttggtaata tttttacatc ataattattt aaattattat tcgtgatact
    22801 attaaataca tcaccttgac gttcaaaaaa aacattatca actattacaa aataaacatc
    22861 ttcttttcta ctattttcaa cctctatagt attttgttta gttacattta gtctcatctt
    22921 ccacctccta ttaatattac ttaattatat taatacttgt aattgttgca ttatgttcat
    22981 cacaaggaag aggtttaaaa acaactatct ctgctaaata attctgtgga ggatttgtaa
    23041 ctgaagtagc attacaaata aatttaaaat ttgttcctgc tacaacttga gtagaaacaa
    23101 taagtggttc ataaccaacc ccttctaaca ttcctacagc ttcattaaat acttttaaat
    23161 cttcttcttc gacagctctg aattttgacc atccaccaac aaaaagactc atataaaaac
    23221 ctcctttata tatatattta tttatatata tagtagtacc aattttctca atattcaata
    23281 ttttctgtgt aactggtcaa tgaaaatgca taactggata aaaatactta taaaataact
    23341 taactttaca tataaatagc ttaatttaca tgtaataaga ttattctaca atatgaaata
    23401 catcttattt tgaatatatt ctaaatacaa taatggatat tttcaattat tatacttaga
    23461 aaatatccat tacttaattt gttttattta aaatcacata gagactttat tatttttttt
    23521 attgcatgaa tagctatttc aggtatcata aggtgatata ccccctcctt gaaaccacaa
    23581 aaaacataac aaactttacg aatcttgtct taaaagacca caggtacatt ccttatttgt
    23641 ggattggagt agccataaca agcaaatttt acaattttta tgatgacaaa aatcaataaa
    23701 atcgcttagt atataacacg aaatactact tgttgctatt aagaatagtt agataggaag
    23761 tatgcattat accaataaag gaatcaataa agaaagttaa aacatcccta caaattaaaa
    23821 atctgttaca tttttctata tttaaacgtt atttacttac aattggagaa ataacaggtt
    23881 ttccttctcg gtcaagtaaa ggcgtaaatc cggctgcatg gccataatag tggaatacat
    23941 agttcacacc tgtttcttta tccacccaaa tctccgttgc atttattttt ccttgtgaat
    24001 atactttttc aaatctatct tttcccattt tataatcctc catatttttg attggtctat
    24061 gccttcttca cttaagtaga aaaaatacat aacttatttt tttaattcta atatgagcac
    24121 gtaaaaatgt caaacagctt atttaatttc ataacttcat gttactgttc gtaaccttgt
    24181 ctgtttactt acactgcatt acagcaccat tttatccttt acattattgt attgcacaca
    24241 gtaaaaatgc ttactttatt ggatttttca actaaaaaaa ggattttttc tccacagaac
    24301 atttactatt ttttataata tatctaattt tactctcata tcaacattta atgaagatat
    24361 aacctttttc aaatattgta aagactcctt aaaaatatta gaaaaagatt ctgcaaatct
    24421 ctcaacatct ccttttttta aatacctaag tatctcaaaa catacatcaa aacgtgtttt
    24481 caaaatttca ttatattctt catgaaaaaa tctctctaaa tagattccaa atatcatata
    24541 ttgttttaaa tgtaaaaatg tttcctgtaa tacataaatt tgtgtataat ctactatctt
    24601 acaaagtaaa acaaaatctg gataaacctt acactcttca caattatttt gtaagtacct
    24661 taaatgagtt tctattttat ctacagctat caaatccatt ttatttccta gtaaaagtac
    24721 tacatcctca agagtaatcg taacaaactc catagcatcc aaaagcaaac tcaacctttt
    24781 agctccttct tctgtattta tataatcatc atcatattca gaaaaaagtg ttatatatgt
    24841 tcccttgcca ttaattgttt tagcaattcc caattcattt agctcattat aggcacttct
    24901 aactgttgga agagatacat tatatctatt aattatcgaa gtaattgatg gtagacaatc
    24961 tcctatttta atattgcctt caaaaatttg acaaattaca tctgaaacaa ttaagtcata
    25021 taaataacat ttttccaacg ttacagaatt aaaactactt gtatctatac tttgtggagc
    25081 acgattttct accattttaa gtatggattc tctacaagct ttatacatat atgttaatag
    25141 ttttttaaat tcaattagat tcccgtccaa tccatataag taagtttttc ttacctgctc
    25201 tatgtattta ttacgaaaaa agtctataca acaattatcc aagttatcca agttatcgaa
    25261 attataggcc aattgtgaaa taatgacatc atgctgaata atctcacaaa aatggtgaat
    25321 caggaaatta tttgttttac ttattagttt atttatatat tttagccttt gttctttaaa
    25381 gactaaataa ttagaactat ttttttccat acaatcgata atctcgttta attcttcaaa
    25441 gtctttagat gtaaatcttt taatattgta catagcaata gaaggaaata ttaaactaaa
    25501 aatcttatat atttctgata tttgtaaaat cttctcatat aataagtcag attctattga
    25561 ttgtttactc gtactctgga ttaaaactgg tctagaacca gcttttgtct ctataaagcc
    25621 cttttctgag agcattttta ttacagtttt tatagtattt tttgatacca tatattcttc
    25681 tgacatgctt tttatagaat caagcctatc tccaatagta attttaccag tataaatttg
    25741 ttgaattata tgctcaaaaa taattaaata ttgtggtttt ctcttcatat ttttcctctt
    25801 cgataaatta gatttattgt tttttgtaag gtatatttac ttttatttaa tagggcaaaa
    25861 tagttgctta ttttttcctc ataatctata attaatatag accatttata tatatggtct
    25921 aagttttata atactgtaat gcagtaaaat agcatattgt agctatacta cagcaaatta
    25981 acataccatt gtagtatatt aattggaata attttaagta cttcaaaatt ccagcaaaac
    26041 atatatgtgt ttttgatatt atgtatattc gttaatagaa tagctatact tgttttacat
    26101 aataaattat atgatacttg ctatatgtaa ttactatatt taatacacat aactattata
    26161 cttactatat gtaattacta tatttgatac acataattat tatacttact atatataatt
    26221 actatacttg gacacataac tattatactt gctatatgta attactatac tttatacaca
    26281 tagttattat acatgctata tataattact acacttggac acataactac tatatttact
    26341 atatgtaatt atactatacg tggacatata gttatcatac atactatatg taattactat
    26401 acttggacac ataactatta tatttgctat gtgtaattat actatacttg gacatatagt
    26461 tatcatacat actatataat tactatactt ggacacatta tcatacatac tatatgtaat
    26521 tactatactt atacacatag ttatcatata tactatatat aattactata cttggacaca
    26581 tagtcatcat acatgctata tgtaattact atacttatac acataactat tatactttcc
    26641 atacataatt actatatttg gacacatagt tatcatacat actgtatatt aagatataat
    26701 actttttaaa ttttatataa cacagacaca tgcaataaaa aagaaggtat ccataataag
    26761 ctctttgcat gtacctaaat aaaaactgta aaatagaata tataaaatct aatctatttt
    26821 aagtaaatac aatttcactt taaaagagga tgtactatga aataccatat atttttaatc
    26881 ataactacta tattaataat cgaactatgt aacatttaca tatgcaaaat agcatctttt
    26941 agaaacaaaa atataactat acataagaat tacaaatata tttttttaat aaaaccatta
    27001 accttcttga taataatatt cacaaaatta ccattaccac tatattatat attgttttac
    27061 atagtaagtc ataaattgct cttaagcaga aaaagttcta ctaacaacca ttttattccc
    27121 aatatggcag taataagttt ttgtatttta caccttatta ctgtaagtac aatatcactt
    27181 gttaaaaata caagtccaga tataatattt gcaaatatga cctataagtt aattagtatt
    27241 ttaatagctt ctattttaga ttttatctta tggtactcta tgaataaaat aaaagagcat
    27301 atttatataa taactcaaaa tcaaatagag ttcagtctat ttttaaaatt tatctggttc
    27361 actttaggat atatattatt tgatagtata caaattacat ttgctccacc aagttctcta
    27421 acttcctact ttatattggg aagtaacata ttattaatct tacaactaat tatattcatc
    27481 aatcatatat attccattga aaaaaatatt tatttggaaa aagaacataa tagactaaaa
    27541 atgataaaac aagaacaatt actaaaagta aatttattaa agaaaaaagc caacattgat
    27601 gaattaacat cagcatataa tcgaaaattt gcttttgaaa aaatacagca ttacattgat
    27661 aacaatttat tattttcatt gatatatatc gatttggata aattaaagac gataaatgat
    27721 acatatggac atttagctgg ggataactat attattaact tctcaagtat agttattgaa
    27781 aacttaggaa tagatgacat atttgctaga ataggaggag atgagtttat agttattatg
    27841 cctaaatcta atgaaaacac cacaaaagaa tttatagaga aaataagtaa aattatggat
    27901 aatacgatat cttttagcta tggtattgta gaagtttcta gcgaaaacaa aatgactgta
    27961 gaagaaatta ttaatattgc tgatattaga atgtacacta ataaacaaaa taatcataaa
    28021 aggaacaata actaaaatga atatttacat gagcttactt gtagtctcac tatgtttttt
    28081 atcttattat ctctatcatt ataatttttt taaatatctg gacataatga ttaataactc
    28141 taaaaataaa tacacagtat atattatata ttctatattt aattatttaa tttttattat
    28201 ttgtacttat ttaaagtttc atctaattat aaattggaca atttttatgt tgattttatt
    28261 catacaaatt aaagtaactt ataaaatctc cacaataaaa aacatttttt attcactaaa
    28321 ctgctccatc attggtttag caataaatat attttttagg tctttaatgt caatagtgtt
    28381 aaatatgcca gcatatttat ttgatagtaa ttctattgca aatatttaca gagtatttcc
    28441 tatatcattt agctttatag ttacaggact atatttcagt tataaaaata ataaaaataa
    28501 taagattaac tttgaggcag ttttagagga caaaaaaaac ttaattttct tattgagcct
    28561 tatgtttgga atgtacttgt atctatgttt gagtttgtca atatactata ctgttggaaa
    28621 tgtattgatt ttaaaattat atggaatcaa gtctgccata atagttttgg taggtaacta
    28681 tattgcagaa agatatagct ttagaattac tcaaataaaa ggttatgata ttaaaaatca
    28741 aatagaatat gtagaaagta taaagacaga gtatgaaatt aataaattga atgatattgt
    28801 atatacagat ttactgacag gcttctacaa tagacctttt gtaaatcaaa aactatcaga
    28861 gtggacatca aatcactaca aatttacctt atgttttact gatttaaata gcttaaaacc
    28921 tgtaaatgat aaatttggac accaatttgg tgataaatac atatccacta ctgctcaaat
    28981 aataaaaaaa cttataaatg tagaaaattc cttactattt agatatggtg gagatgaatt
    29041 tttattcctt ttacagaata caagttgtgt agaagcagaa aagataatga ttaatataaa
    29101 ttatgaatta tcaaaaataa gtaataccga cgagtatcct tatgctcttt ccataagcta
    29161 tggattagtt gagtgggatg gaatatccga tattgaaact ttaatatcaa aggcagattc
    29221 tttgatgtat gaaaataagc ttaaaaataa atctacttta aactagctag ttcagatatt
    29281 ctacaaaata tatattataa gatagtacta agaatgtcaa aatatataga ttttgcaaat
    29341 attgaataca gtttactaat gaatgcactg gatgtaagtg ttagtaaaca cctattagat
    29401 gaacacttta ctgttgtttg ggctaatgac cgttattatg aaatgttcgg ctatacctag
    29461 ctaaaaagtt aaaaatgacc actgtagccg agggaataga gactagtttt caaaaagatt
    29521 tcttgcaaga aatagactgt gatatgttac aaggatacgt gttctctaga cctttaccaa
    29581 taaaagactt tgaaaaactt atgtttcaaa actcctccaa ttaacaatat aaaattgctt
    29641 attataagtg atattattgt atcaacaaat aaaggaattg tctcaaaatt gattttttct
    29701 aatcaaattt ttattttgag acattctcat ttttttgcat aagaaaatac ccaccaagct
    29761 acggtttttc ttaccgctgt tcggtgggta ttagtagtat tatgaaatct gaaaacttta
    29821 agtattacta cttccgctag cgcaatcaca aaggtcgaaa gcttcaaagc gaaaataggc
    29881 tttttactca tcaaacgtca ccgtacctgc caacccgtcc accgttatca tttgtccgct
    29941 cttaatagct cgtgtggcaa tgtgtgtagc cataacggct gggatgccat attcacgtgc
    30001 gacaatgctt gaatggctaa gaggaccacc aatgtccgtt acaatcgcac ttgcagatga
    30061 aaataatggt gtccatgctg gagttgtggt aactgcaacc aaaacacttc caggttgaaa
    30121 gctttcaaaa tctgctggac tattcagtac acaagctgga gccgtcacaa caccagtact
    30181 ggtaccaatg cccgtcaaca caattttccc atctttctgc ttctgttgtg cttgtgatat
    30241 agtttttttg tttttctctg gcaacttgga tggtgacaca taacccatgt attttttaag
    30301 ttcagctttt cgaacaggta ttatcccgtt catatcagat agagacttgt ttttatccaa
    30361 ctgctctata agtacctcca attccgattt tgtgagccaa taaatatcat ctaaatgtga
    30421 aatagctcct cctcgtatga atcgttctga gatttcctga aacatacaac gaatcagagg
    30481 atgtcccatt cccatcaaat aaatagcatt ttcacgcata ggagaggttt cctgtgccca
    30541 atggagcaac ttaaaaaata gttttttacg caatccacct atgtgttgta aaatctcttc
    30601 ttctgcatgt tttctacgct tttcaaacgt ggtctggcgt aaaaaaggac tttccccttt
    30661 tccttccaca aatgttttta cggattcaaa agttggtgta agtgtttcct gcggtgtgga
    30721 atgcgcaaaa tcaaactcat aagcggtacg accaaactct ttaaagtact tattgattcg
    30781 atttttccat tctatccata cttcctgtga aactccaaca ggcacaactg aagacatgaa
    30841 atcttctgct atctttattg caggactgtt ttgcagataa aggttgatgc tgttattttg
    30901 ctttacccat tctgaaatac cccacaactc cttttccgat tgcagaacaa tcgtatcaaa
    30961 cccaagcagg aaaacggaag tatccgttat accagcacgt cgaactgctc cttgaaataa
    31021 ttttgtaaat aatgtttcac tgatagaagc agcaggcaat gtaagctgaa tccttgtgaa
    31081 ataaatacat gcggcataaa atattgtctg aataccctcc ataatttgat gggcgttcat
    31141 agtatgcagg ggcttttctt cccattgttt aatagcatcc tcatatcctt ttcgtgccgt
    31201 ttcccagcgt gcaacgctgt tcataagtgt cctacgtaaa gagcgtgggg aaagggattt
    31261 gatagcaatc aaaagtggat ttgatttagc agaaagataa acatatccat taataaccgt
    31321 atatgccccg ttttttggta ataatttttt cgcactttta ccaaacatat ctatccataa
    31381 aagctctgat gcacggttta cgatttcaag accaagcgtg gcgaacaaag gtgtaacagg
    31441 atttggcaaa tgttctgcca aacttccctt tgtgtataca acatcctgtt ctggcaatac
    31501 ccattctggt ggcagaacag taattggacg agcctgaaca atgtacaatt tatctttttc
    31561 cagtgcccac tctacatcca taggcatttg ataatacttc tcaattttct ttccaagctg
    31621 tatcagttgc attacctgat tacgagtaag agcatatttt tttctcaacc tttcaggaac
    31681 catggtttct tctgttcctt ctgaagtacg aaccgtcata atctctttat ttgccacttc
    31741 atacgatata attcgttcgg agtccttatc cactacgatt gtatcgggtg taactaagct
    31801 agaaaccacc gcttcaccaa gcccccatgc agcgttaata atcatttcgc tacgtctacc
    31861 attgattggg tttaacgtaa acataatacc agatgaatcg gaaaatgcaa gcttttgtac
    31921 tacaacagca agtgcgacaa tctcgtgctt tatattattc ttcacacgat aagcaatagc
    31981 acgagctgtc cataaggaag cccagcatct ctttacagag tcaataactt tatcttcacc
    32041 ttgtatgtta agataagttt cctgctgacc tgcaaaagaa gcgtcaggta aatcttcagc
    32101 agtcgcagac gaacggacag ccaccgatat gttccctaat ccagcataag ccattttaat
    32161 tgcgtccgac acttcctgtg gcatttctcc attatggaaa agctccccta ttttcttaga
    32221 tacatcttca agttggctgg tattattgga atcaatacca tctagcagtt tattaattcg
    32281 agactgaata tggttcgtct caacaaaaat ctggtatgaa gcagtcgtaa catgaaaacc
    32341 gtctggcaca gggatgcctg ctgtcaatag ttttgataaa gacatccctt ttccaccaac
    32401 aatttcaatg gttgcttgtt tatgttccag tggcaagaca taataaatca taatcattca
    32461 cctccatcat tcataattcc gtgcagaaat atattcattg tttcatccaa cattttttcc
    32521 gaactatcca atggtcgtga cgtgtagctg attgataaca tggagttaat taacaaacgt
    32581 gtcacaagag cggtatccgt tttgcgaaag atgcctgtgg tcacaccatt atcaattacc
    32641 gattttataa tatcttgata tgcataacga gcatctttaa gtctctttcg atactcttct
    32701 tctaaataat cagattctgt atttaaccac atcagtacag ttctatactg ctctggaaat
    32761 ctaagatgat taagcatgat ttttctaagg cactgttgtg gtgaaggttc accatcaata
    32821 atcctatgaa cttgttggat agttttttct atttctttct caactgcata tacaacaatc
    32881 tcgtctttcg ttttgaaaaa atcgtataga cttgactttc ccatgttggc taaaactgca
    32941 atttctctca ttgatgtttt ttggaatcca ttttcagcca taagactcaa agcaacagca
    33001 actatttttt ctcggcgttc tgcttgttgt tcgggtgtaa gcacaattcc ttttggcata
    33061 gggcgatacc tccttttagc gaccactggt cgtttctttt ttatttatca tacagcgacc
    33121 aacggtcact tgtcaaggtt aatttttttc attgtatatg gtactcgaga taaaaatgtt
    33181 cattttagaa attgctctat ttaagtagaa ataggcttca tcattagaaa acaagactat
    33241 aaatttgaga tatttatcat gttcaaattt catcaatatc aaagtttaag atattaataa
    33301 aaaaagaatt actaagaaat aacatataaa gattcaaaaa aggagttgaa cttaaaattc
    33361 aattacaaaa aatcaaattt aagacaactc ctttattctt tatctctact attctttatc
    33421 tctatttatt tattacaact ccctaacatt taccactact gccttaggtc tagtcatagc
    33481 ctcgattgaa tacttaacac cttgagttcc cataccagat gcctttacac ctaaaaatgg
    33541 gaagtggtct ggacctcttt cagtcttatt atttatttga acagtaccaa cttcaagttt
    33601 atcagctata taaaatgcct tatcaatatc acttgtaaat actgatgatt gaagcccata
    33661 ctctgattga ttagcaattt caattgcttg atttatatct ttaactctta taattggaag
    33721 tactggacca aatggttctt cccaagcaat tttcatatca acatttacat tatctaacaa
    33781 tgttggatag aataaattat tttttctaac attgcctgtt attaactttg ctcctttatg
    33841 taatgcatca tcaaccaacc cttgaacaaa atcagttgct ttattatcta taagaggagt
    33901 gataactact tcatccattg gatttccaat tgtcaacttc tctaccaatg gctttatttt
    33961 tccgactaat ttatccgcca cactctcttg tactaaaatt ctctttactg ccgtacatct
    34021 ttgtcctgaa tatgaatacg ctccagatac tatattctta gctgcaaaat ctaagtctgc
    34081 atcttctaat actatagccg catcttttcc accaagctcc aataataatg gtaccattcc
    34141 agatatttta gatatatgct gaccaacttc agtactacca gtaaagttaa taaaattaat
    34201 tcctttatgc gttacaacat aatctcctat ctcactaccc ctacctgtaa tagtattaag
    34261 tactccatct ggtatcccag cttttctcat aatttctacc acatgaagtg cgctaatagc
    34321 cccttgtgta gcaggtttta atacaactgc atttccacca ataagtgctg gagcaatctt
    34381 tgacattgat aaatttacag gataattaaa aggagatata gctaaaacag tacctaatgg
    34441 aacccttgaa acataagaca tcttatttct tgttccacca gggaaattat ctccactaat
    34501 ggcttcaccc tccatatttt ttcccacatc agctgtgtat cttaaaaaat ctgctgttct
    34561 ctcaacttct gcccttgcag attttatgtc tttggctatt tcaagtacca gtatattagc
    34621 tatctcatct atattttcta acaataaatc agcagcctta tgaaatatat tggctctctt
    34681 atatacaggc atttcagccc atacttttat actctctttt gtgtttttta taacctcatc
    34741 tacctcatgt tttgtcatag attgtacttt cccaacaaga gaattatcta ttggtgagta
    34801 aatttctatt ggctttctcg aattagattc tacccatttt ccatttatta aatttttata
    34861 tacattttct tttgttttaa gttcattaaa catattttta ttcctctctc tgatataact
    34921 ttgtgtattt aaattatagc catttattcg ttatgtaaac atttcttttt ttcataaacg
    34981 tttatctata aaaaaatttt aagttaacgt ttttctacat tcttctattt taataacata
    35041 ctcgctccaa atctatatag gtcacacttt aatatcaata tactaatata ccaatatacc
    35101 aatataccaa tataccaata taccaatata aatattataa acataaatca cttgacaaat
    35161 ttataagtag acaatattat atatctatga cttaaaatat ttttaaagtc atagatatca
    35221 tatatagata gaaaggattg ataaaaatgg ctaaaagttt tacagaaata gaaaaagaca
    35281 atataagaaa aagactaatt tcagaatgtg aaatcaactg gtctaaatat ggatacaaaa
    35341 aaactaatat tgatgaactt tgttcaaaat caggaattgc aaagggttca ttctacacat
    35401 tctttgattc aaaagaaaag ttattttttg aagtattaaa tggaatccaa aacagactta
    35461 tatcatcagt agatgaaatt ttaagtaaca tgcctccaaa agaaggcttt gcaaaagcct
    35521 taaagatgtt gtatcgatta tatgataaaa acccattctt atattcacca aataatactg
    35581 attacatcac tttattgaat aagataccta aagagatgct ttcacaactt gaatacagca
    35641 atgtacaaag tttttatagc ttaattgaaa gacataatct caagttaaaa atagagaaag
    35701 aaaaagcctt tggtgtttgc aatgccctac tgtcaagcct attgctaaaa gaagatattg
    35761 gatatgacta cattgaagta tttgatttta tggtagacaa tcttgtagaa cacatacttg
    35821 agtaataatt taaaataaat tttctaaaca tttctttata actaggagga gtaatatgat
    35881 tgaattaata caaagactaa atgatattat ttacaaaata aatgataaac taaatatcca
    35941 cacaaaactt gtagacccta gcagtgagct catgccactt tactctatgt tatctataat
    36001 cgtttctata tttctaataa tattaggtat taaagtaaga aaaaaattcc ttataataat
    36061 tgctattata tcaattatta taaatatttt aataatctta gataggtagg tacatatatg
    36121 gtaaaatcct cgaacacttt taataaaaac ttcaacttga tgatattagg tcaaataatc
    36181 tcattgtttg gtgcatcaat acttaaattt gctttatctt tatacatact tgatataact
    36241 ggtaaagcag aaatatttgc tactatacta gcagtatctt caatcccaat tatagtattc
    36301 tcccctattg gtggagctat tgcagatata ttcaacagaa gaaacttaat ggttattttt
    36361 gatttttcaa gtagtcttac agtactaatc ttagcagtat tcttattcaa caataatggt
    36421 tcaatattac ttgtaggaat tattatgacc atattatcag tcataagcac aatgtatcaa
    36481 ccaactgttc agtcaagtac acccctttta gttgataatg agcatttaat gaatgcaaat
    36541 ggtattgtag ctggagttgc atctcttaca aatattgcag gacctgtatt aggaggtgtc
    36601 ttgtatggtg tgattggaat taatgcaatt atagttataa gttgtgtaag tttctttcta
    36661 tctgcaatta tggagatatt tatacagatt ccttttatca aacaagagca aaacagcaac
    36721 attataaaaa ctatatttac tgatataaag gatggtattg ttcatatatg taaagaaaat
    36781 agatttatac taaaaatact ttttttagct atagcaataa acttattttt aagctctatg
    36841 ttaatagttg gtatccccta tatagtaaaa atcactatgg gagctagtaa cttcttatat
    36901 ggtctagcag aaggagcaat ttcttttagt tcactggtag ctgctgttag tattggtatt
    36961 ttctcaaaac atctaaaaat cactaatttg catatttcct ttattatatg tgcagttatg
    37021 ttcataccaa tggcggtttc agtatatcca tttatattaa acacaggatt tccagttcca
    37081 tttttaatct ttatagtatc atctatgcta atatttttta caacgactct tatctcaata
    37141 tatgttataa cagtcacaca attaaaaact ccaaatgaac tcttaggaaa agtaatgtca
    37201 attctttttg caggaacagc aattgcaatg ccccttggtc aggttatgta tggtaaactt
    37261 tttgatttat tatcagatag agtgtacatc attatactag gagttggatt tattacatta
    37321 cttatagcat ttgtatcaaa gataacattg aggaacgaaa atctttagat acaaagaatt
    37381 tagatataaa gatttaattt tcactaattt ctgaatttaa atgcaaaatt gtgtatcagt
    37441 atgttgacgt tttagaaatt gattgatata atcaatggaa aataaacttt ataaaaattc
    37501 aaaatattca gctagaggag tgataaaaat gagttacatg ccaactttag aacaagcatg
    37561 ggaaatatta agaaaataca ataaggaaga atttcatata agacatgctc aaattgtatc
    37621 tggagttatg agatactatg caaaggagta cgaccctgaa agagtagaat tttgggaaat
    37681 agttggactt ttacatgatt tagattttga aatgtatcct gatgaacatt gtgttaaaca
    37741 aagagaatta atgacagagc ttgatttaga taaatcaata atcgattcta caataagtca
    37801 tggatatgga ttaactggtt cagatgttaa accagagcaa tttatggaga aagtattatt
    37861 tgctgtggat gaacttactg gtttaattgg tgctgctgca ataatgcgtc cttcaaagag
    37921 cgtttctgat ttagaattaa aatctgttaa gaagaaattt aaagataaat catttgctgc
    37981 tggctgttct cgagacgtta taagaagtgg tgcagaaatg cttggatggg aacttgataa
    38041 gcttatccaa acaactatag aagctatgag aagcttgatt ccagagatgg caatatagct
    38101 cctccataca tataccatag aagttacatc tttaaagagc atttctcttt ttgatgcaac
    38161 ttctttttat attttgtaga ataaaaagtt taatatttta aactcactat ataatctata
    38221 ataaatacta taaataatat aatgtataat agtcataaac tttctaacct taaaagtttc
    38281 taataatcaa taaacaattc taatatacaa atgtcattat atgatttaat tatatatctt
    38341 caatttatat attaaaataa atatatatat attaaattct tatacacca
//
LOCUS       DAGQVA010000035        37768 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.035, whole genome shotgun sequence.
ACCESSION   DAGQVA010000035 DAGQVA010000000
VERSION     DAGQVA010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37768
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.035"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            265..894
                     /locus_tag="MIV85_001949"
     CDS             265..894
                     /locus_tag="MIV85_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961286.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            1237..1746
                     /gene="ruvC"
                     /locus_tag="MIV85_001950"
     CDS             1237..1746
                     /gene="ruvC"
                     /locus_tag="MIV85_001950"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBY2961287.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            1739..2341
                     /gene="ruvA"
                     /locus_tag="MIV85_001951"
     CDS             1739..2341
                     /gene="ruvA"
                     /locus_tag="MIV85_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBY2961288.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            2448..3467
                     /gene="ruvB"
                     /locus_tag="MIV85_001952"
     CDS             2448..3467
                     /gene="ruvB"
                     /locus_tag="MIV85_001952"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBY2961289.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            3785..4810
                     /gene="queA"
                     /locus_tag="MIV85_001953"
     CDS             3785..4810
                     /gene="queA"
                     /locus_tag="MIV85_001953"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBY2961290.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEYGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            4822..5307
                     /locus_tag="MIV85_001954"
     CDS             4822..5307
                     /locus_tag="MIV85_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961291.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            5386..6507
                     /gene="tgt"
                     /locus_tag="MIV85_001955"
     CDS             5386..6507
                     /gene="tgt"
                     /locus_tag="MIV85_001955"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBY2961292.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            6641..6934
                     /gene="yajC"
                     /locus_tag="MIV85_001956"
     CDS             6641..6934
                     /gene="yajC"
                     /locus_tag="MIV85_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBY2961293.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRLQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            6992..7354
                     /locus_tag="MIV85_001957"
     CDS             6992..7354
                     /locus_tag="MIV85_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBY2961294.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            7420..7563
                     /gene="scfA"
                     /locus_tag="MIV85_001958"
     CDS             7420..7563
                     /gene="scfA"
                     /locus_tag="MIV85_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBY2961295.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            8190..10085
                     /locus_tag="MIV85_001959"
     CDS             8190..10085
                     /locus_tag="MIV85_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBY2961296.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            10547..11950
                     /locus_tag="MIV85_001960"
     CDS             10547..11950
                     /locus_tag="MIV85_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBY2961297.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      12122..12207
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            12331..18294
                     /locus_tag="MIV85_001961"
     CDS             12331..18294
                     /locus_tag="MIV85_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBY2961298.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEANSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPDGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDGLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQEISKGNSDLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGIINNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     gene            18504..20384
                     /locus_tag="MIV85_001962"
     CDS             18504..20384
                     /locus_tag="MIV85_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBY2961299.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVIGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTVGYENINSDEGLVFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTIKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGI
                     EKISNKAIEQVGKIANKDISKNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            20751..22352
                     /locus_tag="MIV85_001963"
     CDS             20751..22352
                     /locus_tag="MIV85_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBY2961300.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADRQTYETVILVNTEKSLADGLSVSGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASKSNRQPPTITVGSTEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSKLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSNEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            22571..24160
                     /locus_tag="MIV85_001964"
     CDS             22571..24160
                     /locus_tag="MIV85_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HBY2961301.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKA
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGAPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYSLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            24373..26553
                     /gene="slpA"
                     /locus_tag="MIV85_001965"
     CDS             24373..26553
                     /gene="slpA"
                     /locus_tag="MIV85_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBY2961302.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPVFAAQTDYQNTYTVVQSKYEKAL
                     KDIQKGITDKKITEVGISYEGKPVTTITVANMDTTGTTSTKEELASALLKTTVNDKLD
                     NLGDGDYVDFDITYVGAADALTAGDLNAFKAALAADTTLKIPVASTTKFGAVVLGTGD
                     TKLDPASSAVNVSTAIEANIVGNTLTVSKKASDATKIGKEDEDNSTATDVTFKDDAKI
                     SVSVGDPKIDLAKSFAFDDTTGKLDGIVEKENTATSHAYVRVINAKEQTIDLDASSYK
                     SAEDLAKAYAFDVNELKTLYTEIEAYQKDSNNKTDKVQIVDGKYQTILYAEGKRLTTK
                     SATQASKLADENSPLKLVIKADKLKDLKDYVEDLRNANNGYSNTVTVAGDDRIETAIE
                     LSSKYYNNSDEDNAITEDAVNNVVLVGSQAIVDGLVASPLASEKKAPLLLTSKDKLDS
                     NVKSEIKRVMNLKTTTGINNSKKVYLAGGVNSISKEVENELKDMGLKVTRLSGDDRYA
                     TSLEIADEIGLDDDKAFVVGGTGLADAMSIAPVASQLNQKGDATPIVVVDGKAKELSS
                     AAEDFLDDSQVDIIGGKNSVSKDMEDAIDDATGKSPNRVSGDDRQETNAEVLKESDYF
                     PDGAVNYFVAKDGSTKEDQLVDALAAAPVAANFGRTYNIKDNDSSGTVSPAPIILATD
                     SLSSDQNVAISKALPSGKSGNNLVQVGQGIANSVINKIKDLLDM"
     gene            26801..29146
                     /gene="secA"
                     /locus_tag="MIV85_001966"
     CDS             26801..29146
                     /gene="secA"
                     /locus_tag="MIV85_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBY2961303.1"
                     /translation="MSVLDTILDKADEQEIKKLNLIVDKIEALEEEIQNLSDDELKEM
                     TNVFRNRLNNGETLDDILMEAFAVVREVSKRKLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYESLGMTVGVIISNQD
                     PNIRKQQYKCDITYGTNSEFGFDYLRDNMVPDLSYKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGDGDEDLKLYELANSFIKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEIISKAGKLDAITIATNMAGRGTDISLGAGDKEEEQEVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIQEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMIGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
     gene            29561..31432
                     /locus_tag="MIV85_001967"
     CDS             29561..31432
                     /locus_tag="MIV85_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HBY2961304.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEAIEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGINLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFIIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNVVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHTTSVAVAKAMGSFKDT
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            31539..32246
                     /locus_tag="MIV85_001968"
     CDS             31539..32246
                     /locus_tag="MIV85_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBY2961305.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELAINKIQYVHAP"
     gene            32279..34114
                     /locus_tag="MIV85_001969"
     CDS             32279..34114
                     /locus_tag="MIV85_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBY2961306.1"
                     /translation="MKISKKIVALLTITFLTITLYGNTSNASTKYTLTGSGRRETAIK
                     ISQAGWKKSEKAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENINFERISGNSRYDTSLKLAEKLNKEKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSDNGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRNKNDLIDSLAVGV
                     LAAKNSSPIVLAGNKLDTVQKDVLNTKIIDKVTQIGGLGNENVVEDILDIQEETKYTV
                     ETIDELNVVIKKADANDIIKFVPEKDRSINSSFKIETDKAIEVELKGVYKQSITINMP
                     NGKISNLGEINGTTEIKNIKNNSFINKGSIFDLDISSNNECKIENESSGEIWLITIFQ
                     NAKGVYIVNDGDITKISNNSSDVIIKNSGEIDTVTGSKEPAISGKKPRINDTKVDDTL
                     ARGLYVKADSCYNPEKDYVMVTILSEPKSSDYSIYYRVVENKPSAMYVGNKINPADWD
                     IVTKYNKEFIEKAKDGSYIEVVEVNSLTNKVSRWGKSNVTNDGVR"
     gene            complement(34157..34552)
                     /locus_tag="MIV85_001970"
     CDS             complement(34157..34552)
                     /locus_tag="MIV85_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBY2961307.1"
                     /translation="MIFKKHKETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIKFLFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFKN"
     gene            34780..37191
                     /locus_tag="MIV85_001971"
     CDS             34780..37191
                     /locus_tag="MIV85_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBY2961308.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTYKRAPLNHAVAIVGWDDNYSKD
                     NFASDAKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVANGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            37488..>37768
                     /locus_tag="MIV85_001972"
     CDS             37488..>37768
                     /locus_tag="MIV85_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBY2961309.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRT"
BASE COUNT        15683 a         4234 c         6917 g        10934 t
ORIGIN      
        1 gcataacata tatggctgtt gttatgtgaa cagttaatta cattacagtt tattctttcc
       61 aaagttatta cctcctaaac gattatttat tataaattat gtccatataa ttacaagaat
      121 ataaccatta agagaaaact accttttaga aaatatctat tcttagagta atttgaaata
      181 taaatatatt ttcttctaaa atttacctaa attgtataaa aacttacagc ttggagaaaa
      241 taatagaaaa aggaggcgta atcaatgttt gaaaagaaga aaaaagaatt atttccttgg
      301 aaaatatctg ccttaatact ggttggagta tttgtattaa gtagcggagt ttatataggg
      361 acaagattaa aacacaatgg agttcaaact ggtgaagttg taagtactag tgcgaatatg
      421 aatgaaaagt caaaagaagc ttttggatta aataaaaatt gtgaagtttg gcttcaaagt
      481 gaaggcgaaa atgaaactaa ctataagaga acacttacaa tggcaggaat agttccagag
      541 tcattattag ataagacgaa gtcagaaata gtatcatatt ttaaaaaaga atatccaact
      601 aaaaaaataa agagtatgga taaaaatgaa atcatattgg tagaatctaa atatagtgat
      661 aataaagatg tacaagcaat ggatgttact ataaaaggta aatatactat tgaaaatgat
      721 aatggaaata tagcactata taaatatgat gatagtggaa gcaaaacatt agtagaaaaa
      781 acaaaaataa gagtagattc acttcctaaa acagttcaag atgaaatcaa aaaaggtgta
      841 gttatggata ctgaagaaga ggcctattca agattagaag actttgcaag ttaatagtaa
      901 attaatatta ttttaagtta aatactaagt aagttaaata ctaagtaaat taataataaa
      961 taatttaata ttaaatagat tagtattaaa tagattagta ttaaaattgt agtcacattt
     1021 aattcctata aaaatacaat aatttatttg taataaatat aaaagttata ttgaggtaaa
     1081 atcttgcttt gatataactt ttttatttga ttttatattt tacatagagc attttatgat
     1141 ttgttaatat tatttatgat ataatgattt agaacataag tttttatgag aaatacattt
     1201 tggtatttct tttattttta gggggaattt taaaaaatga taatattggg gattgaccca
     1261 ggtatagcca tagttggata tggtataatt gaatacaaaa atagcaagtt taaagtaatc
     1321 gattatggag cagttacaac acctgcccat atgaatatat cgagaagatt ggaacttgtg
     1381 tataaaggaa ttgatacaat agtaaagaat tacaatatag atgaagttgg aatggaagaa
     1441 ttattcttta acaagaatgt aaaaacagct ataacagttg cacaagctag aggtgttact
     1501 atgcttgcat gtgctcataa tgggaagcct gtatatgaat acactccact tcaagtaaaa
     1561 caaggtgtag ttggatatgg gagagcagat aaggcacaag ttcaacagat ggtaacttca
     1621 tttttaagtc taaaaaaagt tccaaaacca gatgatgttg cagatgcttt agctgtggct
     1681 atttgccatg ctcattcaaa caaacttgaa aaaactctaa agaatatagg tggtaagtat
     1741 gtatagttat ataaaaggta cagtagaaga aatttatata gacagtatag ttgttgaaaa
     1801 taatgggata ggatataaaa taaatgtatc atccaataca ataatgaatt tacaagtggg
     1861 agaagccaca aaaatatata ctaaattaat tgtaagagaa gatgatatga gtctttgtgg
     1921 ttttgtaagt agggaagaac ttaagatgtt tgaattacta acatctgtat ctaaaatagg
     1981 acctaaagtg gcgctttcaa tactatcatt tgcatcacca gcacagttag gagcatatat
     2041 tttaagtgaa gacattggaa aattatccaa agctcctggt gttggtaaaa agacagcaga
     2101 aagaatcgtc ttagagctta aggataaggt agacaaaaat aacatagagt ttgaaccaac
     2161 attattatca caaaaaccta ccttgatatc acaagatgag tctgtagatg cacttgtagc
     2221 tttaggctat actttgtcgg aatcaaaaga ggcagttcaa aaatgtaaaa aagatggtat
     2281 gaatacagaa gctattataa agaaagcact tacatatata atgagtaaat ccttgaaata
     2341 gtatttggat tttataatat ttggatttta aaacaatatt taaggagttt atgtaaattt
     2401 gaaaatatat aaagtagatt ttcaaaagta tgagaggagg ggtataaatg caaggttttg
     2461 aagatgaaaa taggataata acttctacaa tgaagatgga agatatagat atagaaaata
     2521 gtttaagacc aaaaacttta gaagattatt tgggtcaaga aaaatccaaa gaacaactta
     2581 gtatatttat agaagcagct aaatctagaa atgagcagtt agaccatgtg cttttatatg
     2641 gaccaccagg tcttggaaaa actacactag caagtataat agcaaatgag atgggggtaa
     2701 atttaagaat tacgtcagga cctgcaatag aaagagctgg agatttggca gccatactta
     2761 cgaatttaaa tgaaaatgat gttttattta tagatgagat tcatagaatc aatagaagtg
     2821 ttgaagaagt tttatatcca gcaatggagg atttttgcct agatataata atagggaaag
     2881 ggccatctgc tagaagcata agacttgacc ttcctaaatt tacacttatt ggagctacta
     2941 caagagctgg tatgcttaca aatccactta gagatagatt tggtgttatt tgtaaattgg
     3001 actattatac agttgatgaa ctttcaaaaa tagtacttag gtcttcaagc atcttagatg
     3061 cagagataca gtctaatgga gcattagaac ttgcaaaacg ttcaagaggg actccaagga
     3121 tagcaaatag attactaaaa agagttagag attttgcaca agtcagagct gatggaaaaa
     3181 taactgataa ggtggcaaaa gatgctctgg aacttttagg agtcgatagt ttgggtctcg
     3241 attttgtaga tgagaagctt cttatgacta taatagaaaa atttagagga ggaccagtgg
     3301 gtttagatac attggcagct tctatcggag aagatagaaa tacaatagaa gatgtatatg
     3361 agccatattt gcttcaatta ggatttataa atagaggtcc tagaggaaga gtagctatgc
     3421 cattagcata tgaacactta aaaattccat atcctaatga aaaataaaaa tagattatac
     3481 gagtatttat aaaataaaag agtcattaaa ttaaaatatt tctaaaatgg ctaaaaattc
     3541 aaacatatcc acaaaatggt aattatatct gtagatactg tggataaaca cgataaaaat
     3601 tgtgtgtatt gtatctatat attgtggata agacatgtat atcgtggaaa aatatctata
     3661 tattgtggat atggtgtctg ttaaaaatag caatttcttg atagattatg gtaatattgt
     3721 ggaaaataag ttgttttttt gatattattg tagctggaga aattttaaga gaggaagttt
     3781 aacattgaaa acaagtgatt ttaaatttga cttaccacag gaacttatag ctcaagttcc
     3841 tatagaagat agagctagct caagattgat ggtattagat aaagagacag gtaatattga
     3901 acataaagta tttagagata taatagaata tttaaatcca ggagattgct tagtattaaa
     3961 taatactaga gttataccag ctagattaat aggagagaag cttgaaactg gaggtaaaat
     4021 agagttttta ttattaaaaa gaacagagga agatacttgg caggctttag taaaaccagg
     4081 aaaaagagca aaagtaggga ctaaattttc ttttggaaat ggaaagctaa ttggagaagt
     4141 tgtagattta tcagatgaag gttcaagaat tataaaattc cattatgatg gaatttttga
     4201 agaaatattg gatgaacttg gaaatatgcc actacctcca tatatcactg ctagactaga
     4261 tgaaaaagaa agataccaga ctgtttattc aaagcataat ggttcagcag cagcacctac
     4321 agcaggatta cattttacag aagaattgtt aaataaaata aaagaaaaag gtgtagatat
     4381 agcctttgta actctacatg ttggcttagg aacttttaga ccagtaaaag tagaggatgt
     4441 tttaaatcac aagatgcatt cagaatatta tatggttagc caagaagcag ctgacaaaat
     4501 aaatagagca aaggaaaatg gaaaaaatgt aatatgtgtt ggtactacca gttgtagaac
     4561 tatagaatca gcttgtaatg agtatggaaa gatgaaagaa actagtggat ggacagaaat
     4621 atttatatat ccaggttata aatttaaagt tttagataaa cttattacta attttcactt
     4681 accagagtct acactaataa tgttagtaag tgctatttgt ggaaaggata atgttttaaa
     4741 tgcatataat gaggcagtaa aagaaagata tagattcttc agttttggag atgctatgat
     4801 tataaagtag ggaggtaatg gatgcatagt ttacaaaaac aaaaaaagaa taaccctata
     4861 ttaaagattg cttttatatt tgaacgtgtt ttagcagtag tagttctaat agcagtattt
     4921 ttaggaacta tagatgttct aagacttatg tggggagcat atatagttga ttttcaaaat
     4981 ccagtacaat acagtcagct taatgatttt ttagcacaaa tattactttt agtaataggt
     5041 gttgaacttg tagtaatgct atctcttcat ataccaggag catttattga ggcattactt
     5101 tacgcaattg ctagaaaaat gttgctactg cctaaaaatg aaggtatgat agatgtttta
     5161 ataggagtta tagctatagc aggactattt gctataaaaa agtttttagt aacaaaagac
     5221 aagagtgctc ttaatataat gagtattcat gatgaagaag caattaagga acaacagaac
     5281 aaagaagacg aagataaatc tatttagaca ataaattata tgaatagctt attacaaata
     5341 tatcttaaga aataatgaga aataaatatg attaaggaga actttatgta cgcagtaaga
     5401 tacgaattga taaagacttg taagcagagt ggtgcaaggt taggaagatt acacactcca
     5461 catgggatta ttgaaacacc aatattcatg ccagttggaa ctcaagcaac tgtaaaatct
     5521 atgacaccag aagaattaaa agagattggt tcacaaataa tacttagtaa cacataccat
     5581 ttatatatga gaccaggtca tgaacttata aaaagagctg gtggtcttca taagtttatg
     5641 aattgggata aaccaatact tacagatagt ggagggttcc aggtatttag tctagggcct
     5701 ttaagaaaga taaaagaaga aggtgtagaa tttaggtcac acttagatgg ttcaaaacat
     5761 tttctaactc cagaaaaagc tatggaaata caaaatgcat tgggttcaga cataatgatg
     5821 gcatttgatg agtgtgcacc atacccatca gatagagaat atgtaaaaaa ttctttagaa
     5881 agaacaacaa gatggttaaa aagatgtaaa gatgcccata ataataccga caagcaagct
     5941 ttatttggta taatacaagg tgggatgtat aaagacttaa gggaacaatc agcgaaagaa
     6001 ataactaata ttgatttacc aggatatgct attggtggac ttagtgttgg agaaccaaaa
     6061 ccacttatgt atgacgtgtt agagcataca actccactta tgccaaagga taaaccaaga
     6121 tacctaatgg gagttggtag tccagatgac ttagtagaag gtgttataag aggagtagac
     6181 atgtttgatt gtgttctacc tactcgtatc gctagaaatg gaactgcaat gactagccaa
     6241 ggtaaagtag tagttagaaa tgcaacttat gctgaagact ttactccact tgaccctgaa
     6301 tgtgattgtt atgcttgtaa aaactattca agagcttata taagacacct tataaaagca
     6361 aatgaaatac tgggtgcaag attaataact actcataatc ttcacttttt attaaattta
     6421 atgaaacaaa taagacaagc gataatggaa gatagattac ttgattttag aaatgaattt
     6481 tttgcaaaat atggatatga aatataggtt ttgcactatt aattataatc attttaatat
     6541 ataatattca atagtactca aagatagaga aagtaaattg ttatataaac atttattatg
     6601 atttacaaaa gagtataatt tacaaaggag tgaaaaatta atgccacagc aacaaataat
     6661 tatgagtata ggtctatggg tagtagtaat cgcaatcttt tatttcctaa tgattagact
     6721 tcaaaagaaa aaagacaaac aattaaaaga aatgagaagc agcctaagtg taggagacaa
     6781 ggtcattaca ataggtggaa tagtagctaa tgtagctaaa gttgaagatg atgttgtaat
     6841 attagaatta ggaccaaata gaactaaagt tccatttgaa aaatgggcta taggaactgt
     6901 taaatctaaa aaagaagaaa tagaagaaga ctaaattagt aatttaaaag ccttttctcg
     6961 aatatatatt aatttgagag gaggtttttt tatgggaaaa tctaattata tttttaaagg
     7021 tctaggatat gcatatataa taactttggc tgttttatta gtgtataact tatttttgac
     7081 atttacagat attggtggag ataatataac tatggtctca tcatttataa ctactatttc
     7141 tgcagctata ggagggtttt acacttcaaa acacatgaaa gaaaaaggac ttatgtatgg
     7201 gcttttagta ggacttttgt acatagtatg tatttttttg actgtgtttt tagcacaaga
     7261 aaagtttgta tttgaaatag ggatgattta taagttattg ctaatatcag cagcaggagg
     7321 cattggaggc gtattgggtg tcaactttaa atagagttta tattaaagta gttttatgat
     7381 ataatcaata ggaaacaatt agaaatggag gcgttgaaaa tggaaaataa acatgtaaaa
     7441 actttatctc aagctacttt aaagcaaagt gctgcaaaag gtggatgtgg agagtgtcaa
     7501 acttcttgtc aatcagcttg taaaacttct tgtacagttg caaatcaaga gtgtgaaaga
     7561 tagaaaatta ttgatttagt tgtttgtaag agggtatctc aaagtgattc ttttatcatt
     7621 atgaggtatc ctcttttatt ttcaattatt atataaaaat atatattcta tttatgtaga
     7681 agtaaatttg atttcttatc gtttaattat gcaaaaatat ctaatcatgt aagagcattt
     7741 attttaaagt agctactctt atattttatt ttttatcaat tacatgtatt agaataattt
     7801 ttaattttaa actctaattt atgatgattt ttataatatg ttatatattt taatatatgg
     7861 agatagatat taatttagtg atatatattt aagtaataag agtaaagcaa aaattagtgc
     7921 atagtagtat ataaaaatgg agtttgaata cttttgttag tatatgattg tttagtagaa
     7981 aatcactata aaataggatt tctatctttg agcataatta tagagagcct aagtaggggg
     8041 aagggtttca agaagatatt attagtgttt gtgttagtaa attatgtaaa cacataaaat
     8101 atattgaaaa ataatattat atataatatt atttatgtgt gggaaatacg aatataaaaa
     8161 ataaaaaata atattcggag gacataaata tgttaagcaa caaaaagaga agtatggcaa
     8221 tagtaatggc aggtgctaca gttatgagtg cagcagcacc aatattcgca gacaataccg
     8281 tgacagaaaa tgttgataaa aattacacag taagtgcgaa agattctgct aaactaatcg
     8341 aagaggttag aaaagcatta gaagttaagt ttgaagatac aaaagcagga gcaaatgtaa
     8401 atgatagagt ttacgatata aaagtagaca atgtaaactt aactaatgca actcaattac
     8461 aaaataaaat aaactcttta acagaagggc aaagtttaaa agttactatt caagataaag
     8521 ggcatcaagt gttaggtgga aaagtagttg actataaaat tgaaaactac aaaactgctc
     8581 aagaaatagt agatgcagtt aatgcttaca atgcaacttt agcagaagat tctgataaca
     8641 agttaacagc aactataaaa tctacaaata cagttgaagt aaaaagagca aaagattcag
     8701 caaatgttat tacattaaat gtaggagacc aacatttaga tttctcaaaa gtgataacat
     8761 cagaagaagg tacttttgaa ggttatgaaa agagttatag tgacatagat tcaaaagaat
     8821 tacatacgat aacagttaaa aacgcagatt tacaagacat atcagcagaa gaattatttg
     8881 atggaattag attaactaca ttaggaagag aaatagttaa taaagttaaa aatggatatg
     8941 ctttaacatt tgaaaatgaa gcaatcctta ctcaagaaca agaagatagt gatgataaag
     9001 ataaaccaga aaaatcaagc tttgatatag ttttaagcaa ggcaaatgaa aagccagaaa
     9061 caataagtgt ttcaagtaaa aaccataagt tagttagaga cttacacaaa gtattaactg
     9121 atgtaaaaga tggaaaagaa ttaaaagtag aagttttatc tggtgattca agatttacaa
     9181 cagcagtaga agttagtaaa gagagattta aagatggaga agcagaagct ataattttag
     9241 ttggagaaga tgctatagtt gatggattag catcagcacc acttgcctct caaaaaaatg
     9301 caccaatatt attatctaaa aaagattcac taccatcaga aatagaagct gaaatattaa
     9361 gagtacttgg aagtaatcta tcttctaaga aaatatatat agtaggtgga gaatctaaag
     9421 tatcaaaaga aactgaagaa aaactttcta aattaggtgt aagtaaagtt gagagagttt
     9481 ctggagaaga tagatttgaa acttctttag aaatagcaaa acaattaaaa gatacattta
     9541 agactgcttt tgtagtaggt ggaaatggag aagctgatgc tatgagtata tcagctagag
     9601 ctgctcaatt tggtgctcca ataatagtta caggtaacga attagatgca aatgctgaaa
     9661 aattattaaa aggaaaagaa ttagaaatag tgggtggaga aaattctgta tcaaaagaag
     9721 ttgaagacaa attagttgat atagatttaa ataataaagt tgaaagatta gctggagaaa
     9781 atagaaaaga tactaatgct aaagtaatca ataaatacta tgcaggtgca actaaagcat
     9841 atgtagcaaa agatggttat gtaggtggaa atggacaatt agttgatgca cttacagcag
     9901 caccacttgc agctagttca aaggctccaa tagtattaac tacagaagaa ctttctaaat
     9961 cacaagaaga agtagttgag ttaagactta agaatgctac taagttagta caaataggtg
    10021 aaggaatagc taaaaacgct attgaaaaaa tagcagaaaa aataaactta tttactaaga
    10081 actaataaga tataggaatt aatattaaaa gtttatttag ataatatatg attatacaat
    10141 gcgttaatat gtaagacata gtgtagatat tataaaatat acaaataaca agataaaata
    10201 ataaaaataa ggtgtctcat ttagaattag attgagatac cttattttat tttttgatta
    10261 taatgttgag aaattcatat tgcaaaaatt attataaaaa gatacttctt ataatgatta
    10321 aacatattac taacataaat tattttgaac ttataacgta attaaataaa ataaattata
    10381 atgttttgaa tttatagaga ataaaaactt taggtatatt gtttgagttg tatggataac
    10441 tatggtatca tatataaaat atggtaacaa aattgtaact tttgattaaa aataagtatg
    10501 agtactaata aaaaatatga aaagtacatt gggggtagaa aataatatga agaatagtaa
    10561 aaagatatta gctataggac ttacactatt tttagtaatg gtaaatactc ctatggtaaa
    10621 tgcgttgaca tcagttgagc aaataaaagg gaatgacaga tatgagacag cagcaaaaat
    10681 agcagataag caaaactaca atacagcaat actaatcaac tcagataata gcttagcaga
    10741 tggtctaagt gcaagtggtt tagctggagc cttaaatgcg cctattttga tgacaaaaca
    10801 aaaccagatt ccaaacacaa ctatggaaag attaaacaaa gcaaagactg tgtatataat
    10861 aggttcagaa tcaacaataa gtaaaaatgt tgagaatcag ttactatcca aaaagaaggt
    10921 tgtacaaaga atatttggtg aaaatagatt tgatacaagt ataaaaatag ctgaaaaaat
    10981 caaagaaatt aagccaatag ataaagtaat tatagccaat ggatttacag gagaagcaga
    11041 tgcgataagt gcatcaccag tagctgctag agatggagta cctataatac ttacagatgg
    11101 aaatagtgtg ggatttgaca cgacaggctt aaagagttat gcgcttggtt ctagtgaaat
    11161 aataagcgac gaattagtta agagcacaaa ttctattaga ttgggtggca cagatagatt
    11221 tgaaactaat aagatagtta tacaagagtt ttataaaaat agtaaagaat tttatctaag
    11281 taaaggctta caattaacag acgctttggc tgcctctaca atagcaaaaa atgctcctgt
    11341 agttttagtt gaaaatggca gtaacaagag tattttaagt ggtgcagaca aattgactgt
    11401 actaggaggc ataaatcaga atgttatcaa gcaatgtata aatcaagctt caccaaatca
    11461 acaaggttta tattacaatc caaatgatag agcatttaaa gagagaataa agggtaaagt
    11521 atatgctctt acaaagcagt atagaaaaga gaatggagta agagcgttat ctgtagcaag
    11581 cagattagag ggtctagcaa atgattggtc taatttaatg gcaaataaga agactttatc
    11641 tcatacgata aatggaaaaa attcatattc tacttttttg aaatacttag attggagtga
    11701 gattaaacct ggatatatag cagttcaagg tgaaaatata attaaatata aaattccaga
    11761 taaacctgta tatacaaata gagatgcaga tgatatagga aactttattt ttaatgagtg
    11821 gaagacaaat ccagaagaag gaactaatat gttgcataaa gggtatgaaa taatgggatt
    11881 tggtatagct ataacaggag ataagaatct atatgctaca catgaatttt atggaagata
    11941 taaagaataa gaaaatatac acaaaattat gcttgtaagg aagctatata aataattaaa
    12001 ttataatgga aaatagcatt tatattaata aattaatata aatgttattt ttttataatt
    12061 taatctaaaa aaattatatt aaaaagttta aatatagtat aaaatgggta agaaagtagt
    12121 gaaaattaaa tggcaaaatt agggaaatct aatgacgcaa aactataggg attaaagctt
    12181 ttaaagccat atcagccagt tgctaaaaag agtaaagtct ttttatttta taattaagat
    12241 tctctttgag tgtctttttt tattgtctga aacttatagt atttaaattc atgaaaaatt
    12301 agatatttat taagggagga ttgttatttc atgaaaaagg caatatcttg tgtactagca
    12361 gtatctatgt gtagtgcacc actaaacgtt tttgcagaac ctatattaga ggggaagcta
    12421 agggcagttg aaaaatcagt tacagaaaag ttaaggggga gtcttgaagt agatttaaat
    12481 ttttcactgc caataaaaaa tagcgagtca gaaagtatga ctaatatgca gttacgatta
    12541 aaagatgata gtaacaatag tggaataata aagcttggag aaaaagattc aggaacagta
    12601 aatgttggga cagataatat agaatatact ataaaaaaat tatctgcaag tagaagtgaa
    12661 ataaaaaata aagatgagaa tatatcatat tataatattg tatttaataa tttacctgtt
    12721 ggaaaataca atgtagaagt ctctggagat ggatttaaga acaaagaaat taaagacatt
    12781 gatatatcaa gttattcaca aagagtctta ttaagcaata gagcaagtgt agataataaa
    12841 aataaacctt taaattatga attgttctta atgggtgatg taaatggaga cggtaaagta
    12901 gataagagtg attataataa ggttttagag aatatagatt caaataaaag agaatttgat
    12961 ttaaatagag atggaaaggt agatattgtt gacttagatt atgtacagaa aaatttagga
    13021 caaagtgaag atgcaaaaag cctagaaagt atagtatcta ccaatcctat agtagataca
    13081 agtaaggttg aattaaaagg aaatagtgat gtagatatta atggtaatgt agaaaattta
    13141 tttagtggag aaaataatgg agttacaata tcttcaaaaa atgatgaaat atctgaggaa
    13201 aaaccagcag taatggatat agctttatca gaagcactta atatggaagt catcaatata
    13261 aaagctccag aaggtactgc tccagcaaaa ggaatagttg aggttactga caaagatggt
    13321 aatgttcaac agattcctta tgaaaacaaa gaatatatga aaaacttaaa agatgaggag
    13381 caacaagagg aagtaaataa cgaacaagaa gaagtaaatc aagaagaagt aaataataaa
    13441 gatgaaaata taaaccagac tgataataac tcaaataata aagatgaaaa taatgataaa
    13501 caacaggaaa atagcgataa acaagaagca aactctaata ccaatcaaga taaaaataat
    13561 gataaagaaa attcatcaat ggataaacct aattcagatg aagatactcc aaaagaagag
    13621 ggtaatatca gtaaagatga taactctaca acatctacat atagtaggtc agcattagaa
    13681 acatatgcag atgttcaaaa tagtgatata gtaataaatc ttggtaaaca agtagcagta
    13741 aaaaagataa ctataaaaat aacagctaca acagcaaacg atagaaatct tgcagaaata
    13801 tcaaaagttg aatttttaaa caatgtatat aaagaaatac caaagccaga gatgaacata
    13861 cctaaaataa ataaaatatc gactagcact gctgttggaa atgaaaaagt atctttttat
    13921 tggaataatg aagtaaatgt atcagcatac gaacttatac tagacaaaat tgatagtaag
    13981 ggaaaagtat tatctactaa aaaattacaa actagtaaaa atacaataga agttagagat
    14041 atagaagcat atggactata tagagttagc atacaatctt taaatggaga ttggtctagt
    14101 ggttataaag atgcaacacc agaaaactta gacggagtac cagaaaatgt agattcaaac
    14161 tataaaccta tacaatttag cccagatagt atattagaat ttcaagttgt tccagacaca
    14221 aaaccagaac caccagaagg tataaatgtt aaaggtaaat ttaaatctct tgatgtaagc
    14281 tggaaaaatc ataaacaagc taaagatttt gacttgtact ataaagaaaa aggctctaat
    14341 gggtcttgga taaaatacaa tgataagctt attcgtggga caagttcaaa gatagaaggt
    14401 cttaaggata atacaacata tgaagtcaga atgacagcta ctaaccactt gggaactagt
    14461 ggaatgtcta aaacatatat aggtacaact gaaagcatgg atgcaccaac aacacctaac
    14521 tatagattaa ttaatactcc taaagaaaat ggtggatttg gaataccaac aaatcacatt
    14581 gtagatgttg tttatccaga tggatatgac aaaagtgaat atagtgataa aaatccattt
    14641 gataaattca atgtagtaga tggggacttt acaacacatt ggacattccc aacatataat
    14701 gcagctgagg gaacgaatag aggaccaata ataacttttg ataaatctta tactatggat
    14761 acttttatgg ctacacctcg ttttgatgtt tctgataaga caataaatga ctttgaggta
    14821 cgatattggg atgaaaatgg tcaattacac aatctggggg atgttccttt tgaaacaaag
    14881 acagaccctg taaataataa taagtatgta atggttagat taaaagaacc aataactgct
    14941 accaagatac aagtaagtgt ttgttcatcc tattcatata agtctaatat atcagaactt
    15001 aagttttatg agtatgacag tatagaagat gatgtaagaa atctatttat ggatggccta
    15061 caagttgaat taaaagaaga tgtaactcaa gaaaaaataa ctgaattaaa agatagatta
    15121 aatactccag ataaagctag tggagaatat catccatata agacagttat tgagagagaa
    15181 ttaaaattag ctcaagactt atataatgat agagccacac ttactgatgt aactactgta
    15241 aatcaagaaa taaataaatt aggaaaatat aaagataaaa acggacagta tactgtaaat
    15301 tccaataatt taggtatgca aaatgactgg caggcattag gagtagctgc tagagcagga
    15361 gatgaaatca cagtatatgt tggaagtaaa agtggaaaaa ctcctaagtt gatatataca
    15421 cagtactatg gagaatctgg tgcatataag agtggagaaa taaatcttaa cactggaaaa
    15481 aatgtaattc aattaagcaa acttcatagt ttagatatag aatgtggagg aagtttatac
    15541 ataagatacg ctgaagatac tccaagtgga ggagatataa aagtacgtgt agcaggagct
    15601 actaagatac cacatcttaa tctaaatgga acaataaatg ataagagtcc tgcgggagtt
    15661 tctgaatcta agaaaaagat aaaagcatat atagaagaat tagctaaata taaagatgct
    15721 gtaaaaggag aaccatatta tccaggaaca aatgttggta attcatatgg atattcagaa
    15781 aaaactggtg tgttaaacac tacagatatt gaaagtgata aagtaacatt aaatgttcct
    15841 gcaacagcag tatatcaaga gatatcaaaa ggaaattctg atttaaatac acaagtagat
    15901 agattatata atagtatgct tgcatgggaa caaataatgg atttagttta ctcagaaaga
    15961 ggagtattta aaacacaaga tttagatggt aatggaactg tagatgataa tgaatttaac
    16021 ttaactaaaa atgatatggc tccaaaatct cgtatgaaca taaaatacca aagaatgttt
    16081 attggagcat ttatgtatgc ttctggatta catgtaggag tagaatatgg ttcagttcca
    16141 gggcttatga atggagtacc tttccaaata gatgatagtg gaaaagctac aggaggaaac
    16201 ttatttggat ggggaatagg tcatgagata ggacatgtta cagatattgg aaagatgaca
    16261 tatagcgaaa ctagtaacaa tgtacttgct ttacttgctc agacctttga tgataagaca
    16321 cattcaagac ttgaaggttc aacaatggat aagatatatg agcatgtaac ttcaaatagc
    16381 ttaggtatac caagcaatgt atttgaaagg cttggaatgt tatggcaatt acatctagct
    16441 tatgatgatg attttacggg ttcaatgtta aagaataact cagatgctga tttaagtaat
    16501 gatacattct atgcaaagat ttcaagaaaa tacagagcac tttcaagtag tgacccaatt
    16561 aatagtttac caaaagacca aatgctagta gcaatggcat caagtgttgt tgaaaaagat
    16621 ttaagagatt actttaaggc atggggagta gaaattacac cagaattaaa cagtataatg
    16681 gatagcaaga actacgaaaa agaatcaaga aagatacaat atgtaaatga tgaagctaga
    16741 agaaagattt taaatgaaaa tatagctagt atggcaaaag atactaaagt aagtgctagt
    16801 ttttctgatg gaatacaaag tggttctcta gttaaatcta ataaaatatc tatagaccta
    16861 gatgtagata aggataaaga taagatacta ggatacgaaa taataagaag tgatggaaat
    16921 tatttagatg gtgaaaatgg aacacaggta aaatacagaa cagttggatt tgtggatgca
    16981 aaaggaaata gcaagactaa atttactgat aatatatctc ctcttaataa cagagcattt
    17041 acatataagg tagttgcata tgattatcac ctaaatccaa cagaagaatt tgaagttggt
    17101 actgtaaaat tatcagatga agggaaaata aataaatcag catggtcatt cataacaaat
    17161 actgtttctg acggtgatgt tagaactgaa aatgactcac atggaccatt acaaaatcct
    17221 gaaattgata atataaaaga taatgatgca agtactacat ataaaggaaa gataataagt
    17281 aaagcagagt ggaacaaaga ccctcaaaaa gaccctgata taaatgtaga agaaaatcca
    17341 tatataatag tagacatgaa agaaacatta cctatagtag gactaaaata tacaaaacca
    17401 gagacagaag ctagaaagtt ctcattaaaa ggattattta actttagaaa gaatactagc
    17461 acaacataca atcctttaac taattacaag atacaagtaa gtaatgataa aaagaactgg
    17521 gaagatgtaa gtcaaggaac ttttgaatat ggacaagatt tagttggtgg aggaaaagac
    17581 caagataatg aagctagagt tacatttaat aaagatggta aactttggac ataccaagct
    17641 agatatgtaa aactaatctc aaataataag tctaatatag aagttgcaga attagatata
    17701 ataggacctc caggtgataa tatagaaatt ggcataataa ataatgcaga cgaaactcgt
    17761 actaatggaa ttggaaaatt agcagaagat tatgtatatc aaagtgatga ctctagcaca
    17821 agtgaagatg aaacaggtaa gattccagcg ggttcaatag ttattacagg tgaatacagt
    17881 ggaaatccag catttaattt accactactt atagataaaa acaataagac tatatctgga
    17941 gaagcacttt tatttgcaga agttccagaa aaaggtgaac taggtgaaat cagtaaaggt
    18001 acatgggttt actatatgcc aaaagaaaac tttgattctt taagtgataa ggttaaggct
    18061 gaactatata gatacaatga ccttcaagga gatactccag taggtcaaag atttgtaagt
    18121 gatacaatgt atgtacctgt aggagctaag aattatgatg agttaaagac aataagtctt
    18181 actgatagta atagtaaagc tagaaaagct acaagaaatt ctattgatat cagcaataag
    18241 aaggttataa ctgtaagcaa taaagtaaag ggtaatattg ttagagataa atagtaggtg
    18301 gaactctaaa aacgtgaaaa tactaacact aacattgtat atctaatatg attaggtact
    18361 agaatagttt taaaatagta gatattaaaa gtaaagtata taaatgtaac cataagttta
    18421 gggtaattta taaattaaat ataaaagcta ggtggataag taaatttatc cacttagtta
    18481 atgatagata aggacgggtg ttaatgagta aaagaaaatc ttttataaga actatagcag
    18541 tatcaactat ggcagtagct gtaattggta gtgctacatg tgcatatgca gctccagttt
    18601 tacaaggaac aaaaacgtat gagaaagtaa atactataga tatatctgtg gactcagtag
    18661 aaaatatagt atattcattt caagccagta taaaagtaca aggtgaggtt gaagtagtag
    18721 ataatgagca gaaagaaaag attacttggt ctgataatat aaaatctcag ataaaaagtg
    18781 gaaatgcaaa tgctacttgt agagcagaat acaacaaatc aagtaataca actacattag
    18841 atatatatgt tacatcaaat gaagatttac tagacggaaa tagattgaat ataggaagaa
    18901 tatctgtaaa aaaatctggc agtaactcaa atgctgacta taaagtttta ggaaaaggaa
    18961 caagcgataa accagcctta aaaattgtaa catataacaa caaaacagtg ggttatgaga
    19021 atataaactc tgatgaagga ttagtattta cccttattaa tgagagtgaa gtaaaaccaa
    19081 ttggtggaac tggttctagt aaaaatgacc ctgaaaagta taaggtagag aaaagtgaag
    19141 cacttgaata tttattaaac aatattagga taaactattc tattgttagt aaagaaacac
    19201 aagaaagtgg ttcaaatgta atattaaaac ttggattagc acaaaaaaca actaagggaa
    19261 gaaaagctac aataaacaag tatgttgaag ttacacttcc aaaaagttta gaatacatag
    19321 ttgaaaatga attatcaaaa ccggatgaat taccaccaga taatggcaat ggtggaaata
    19381 atggtggagg aagtaattca ggtggctcat ctagtggtgg aagctctgga ggaggaaatt
    19441 caagtgattc tacatctaat gtcacaatca aaaaattaaa aggtgctgat agatttgaga
    19501 cagctatcaa aatatctcaa agtggttgga caaaatcaga tacagttgta atagtaaatg
    19561 gagaagataa aagtatggtg gatgggctta cagctacacc acttgctagt gtaaaaaact
    19621 caccgattct tttatcatca aatgaaaagc ttcctcaaaa aactgtagaa gaattgaaaa
    19681 ggctaaatcc atcaaaagta attgtgatag gtggaaacaa ctcaatgcca aattcagttg
    19741 ttgaagctat caaagctgta aattcaaaaa tatcagtaca aagaataggt ggagatacaa
    19801 gatatcaaac ttctattaat atagcaaaag aaatagataa gacgaataat gtaagcaagt
    19861 tgtatatagg ggcaggaaat ggagaagctg attcattatc aatagcatca ctggctggta
    19921 aagaaaaaac tccaatagta cttacacaaa aagatggtgt agataatgaa gctgaacaat
    19981 ttattaaatc aaataaggtg tcaaatatat actttattgg tggaatagaa aaaatatcta
    20041 acaaggctat tgaacaagtt ggaaaaatag caaacaaaga tatatcaaaa aatagggtgg
    20101 caggtcaaac tagacaagag acgaatgcca aagtaataga taaattctac tctcaatcta
    20161 aactagatgg agttgtagtt gcaaatcaag ataaacttat agatgcttta gcagttggac
    20221 cattagcagc taaaaacaat tcaccagtta tacttgctac aaatacgtta gataaatcac
    20281 aagaatcgtc attaaaaggt aaaaattcat caaagttgtt tgaagtaggt ggaggaatag
    20341 cctcatctgt aatagacaag attaagagtt taattgaaaa ataaatatta agtaaataga
    20401 aaataagaat gtatttagat ataaagttat atatttaaat gcattcttat tttattttca
    20461 ttatcttaac aatctaataa tattgaggtt aaaatgtata ataatttgag ctatattaag
    20521 tttaatttta aataaagcag atatctttta tatatataaa tataaattca attttgaata
    20581 tgttcaaaaa gaagttaaaa ataatttttt aaatttaata aaataaaaca ctaatatata
    20641 gacgagatat attcatatca tatatactct ataatatatg gaaaataaag agaaaataaa
    20701 tggaaaataa tcacaatata aatataaaat ataaaaatca tcagggggat atgaaaatga
    20761 acaaaaaaat attatcatta ggtctagcag tatcattaat cttagtaaac ttcaaaagtg
    20821 taaatgcatc atcagtagta gaaaaaatat acggtaaaga tagatatgaa acagcagcaa
    20881 agatagctga tagacagact tatgaaacag taattttagt aaatacagaa aaatcacttg
    20941 cagatggatt aagtgtaagt ggattatcag gtgctacaaa agcgccaata ctatttactc
    21001 aacaaaataa gataccagca gatacaaata gatgtttaaa aaatatcaaa aaagcatata
    21061 taataggtac agaagatacc ataagtaaat cagtagaaaa agaactagat tctaaaaata
    21121 tagaagttaa aagaattggt ggagaagata ggctaaaaac aagctattta atagctaaag
    21181 aaatagcaac tataaaaaaa gtagataaag tactattaac taatgcatat agcggagaag
    21241 cagacgcaat gagtgtatca tcagtagcta ctagagatgg agctccaatc atacttacag
    21301 atggaaagag tgtgcctttt gatgtaaaaa atattcaatc atattgtata ggttcagagg
    21361 agataatgag taatccttta gttaaaaata caaactcagt aagaatagaa ggaactgacc
    21421 gatttgaaac taacaaaaac gtaatagact acttttttaa tagtgcagat ggattctatg
    21481 tatcagatgg ataccaatta gtagatgcaa tagcagctgc accacttact aaaaactctc
    21541 caatggtact agtaaatgat ggaagcgata agactgtatt agaaggagct aagaatataa
    21601 cctctgtagg tgaaataaat gagaaggtaa tacaacagtg tataaatgct tcaaagtcaa
    21661 atagacaacc accaacaatt acagttggaa gtacagagat atataagggt gaaaagtttg
    21721 acactggcaa gttaaatata gtagctaaag ataacactgg gaaggtatta ccaatagaag
    21781 ttgatgggtt tatagataca aatagagtag gtacatacat attgacatta aaagctacag
    21841 acgaatgggg aaaaagcaca ggaaaaagag tagaaataaa agtgttggat gacaaatctc
    21901 atgattacaa cagcccagaa tttaaaaaaa tggtatctac tgaaatgtat aacttaatca
    21961 attcctatag aaaagaaaaa ggcaaagagc ctttggtagt atctagtaag ctagaaggta
    22021 tggcaaatgc atggtctaag tatatgatgg ataaaaaagt atttgcacat tatatagatg
    22081 gaaaaaatgc tccacaagta ttttctgagt ttggaatgag aagtgaggaa aatatagcat
    22141 atatttatat agattctaag aacgttcaaa cgacacaaga tgcaaaagac ttggcaaagg
    22201 ctatatttga ggtgtggaag aagtctccag agtacaatgc aaacatgctt agtaatgagt
    22261 tttatagtac tggatttggg ctttatatat tatctgatgg tcaagtgcat gctactcaag
    22321 agtttttaaa tggcaatgaa ggtagcttgt aaaaaattcc ataaatcttg tttttttgtt
    22381 aatttactga tattataaaa tgaaaatcac atctaaagta ctttttgtaa tctgttttgt
    22441 tattgattta caggttatgg tattttaggt gttttttgtt ttaggagttt ataaattttg
    22501 agggaatcac tactgaggat gtaatttatg attagctgaa ttatataaaa aaattagtag
    22561 gaggagttcg atgaaggtaa ataagagagt attatcaata ggattgacaa tatcattaat
    22621 aatggcagga gcaccaaata tcaatgcact ttcaagtata gaaaagatac aagggaaaga
    22681 tagatatgag acagctgcca aaattgcaca gaaacaaaca tatgaaaatg tagtattagt
    22741 aaatacagat aatacactag ctgatggatt aagtgcaagt ggattagcag gaacagttaa
    22801 agcacctata ttattatcac aaagaaacag tataccatca gacacagaaa aaatgttaaa
    22861 agatgtaaag aaggcttata taatagggac tgaagattca ataggaaaat cagttgaaaa
    22921 tgaattaaag caaaaaggaa tagaagttaa aagaataggt ggtaatgata gaattgaaac
    22981 aagttatctt atagcaaaag aaatagcttc aataaaacct atagataagg tttttataac
    23041 taatggttat acaggtgaag cagatgctat gagtgcgtca tcagtagcat caagagatgg
    23101 agcacctata attttaacta atggtaaaaa tgttccattt gagaaaaaag aaggtgtgca
    23161 atgttatgct cttggttcag aggagataat aagtaatgat ttagttaaaa aaactaatgc
    23221 agttagatta gctggagaag atagatttga gactaataaa aaagttataa aacattttta
    23281 tagttcagca aaagaatttt atctttctaa aggttatcaa ttagtagatg cagttgctgg
    23341 ttcttctata gctaaaaatg cacctattgt attggttgat ggaaatagtg ataagtctgt
    23401 acttagaagt gctgataaga ttacagcact aggaggaata gatgaaaaaa cactagaaca
    23461 atgtttaagt gcatcatcac tggatgcaag tgcaccaaca ataactgttg gaaatttaaa
    23521 tatttatcaa ggtgataagt ttgatataag taaactgaat atcgtagcaa aggatagcaa
    23581 tggtaatgat ttgacaccag agcttatagg aaatattaat actgataagg ttggtaaata
    23641 caaagttact ataaaagcta ctgatattgg tggaaagact acctcaataa gtgtagaagt
    23701 aaatgtactt gaatataaga ctaatgatat gaatagtagt gagtttaaaa gaatggtttc
    23761 tagtgaaatg tatagtttgg taaattcata tagaaaagaa aaagggaaag aaccattaca
    23821 agtttctaaa aacttagaag ggctttctaa ttcctggtct aagtacatgg cagataaagg
    23881 tcagttttca catgtaatag atggtaagaa atctgttgaa gtatttactg gatatgggtt
    23941 gagaagtgaa gaaaatatag cttttgtacc acttgttaca aagagcactt atacgacaaa
    24001 ggatgctaga gaagtagcaa atgtaatatt tacagtttgg aaaaaatcgg ataaatataa
    24061 tgaaaatatg ctaaacagtg attttgtata tactgggttt ggactgtata tattgcctaa
    24121 tggagaagtg tatgctactc aagaattttt aaataagtaa aattaaattt tttaagttat
    24181 taaatattga aatttaaggg tataaaaact catatgcttg ggaaaaataa taatttcaaa
    24241 aaaatgcctt gcaaaaagaa ttaaaatgga ttattataga gatgtgagaa atattaggaa
    24301 tatatggatg attattctat gtacataata aagagatgta attttaatat aatgttggga
    24361 ggaatttaag aaatgaataa gaaaaattta gcaatggcta tggctgctgt tacagtagta
    24421 ggttcggctg caccagtatt tgcagctcaa actgattacc aaaacacata cactgtagtg
    24481 caaagcaagt atgaaaaagc attaaaagat atacaaaaag ggattacaga taaaaaaata
    24541 actgaagtag gaatatctta tgaaggtaag ccagttacta ctatcactgt tgcaaatatg
    24601 gatacaacag gaactacttc aacaaaagaa gagttagcaa gtgctttatt aaagactact
    24661 gttaatgata agttagataa tttaggtgat ggagattatg tagattttga tataacttat
    24721 gttggtgctg ctgacgcact tactgcagga gatcttaatg cctttaaagc agccttagca
    24781 gctgatacta cattgaaaat acctgttgct tctacaacaa aatttggagc tgttgtatta
    24841 ggaacaggag atacaaaact tgatccagca agtagtgcag ttaatgtaag tactgcaata
    24901 gaagctaaca ttgttggaaa tactcttaca gtaagcaaaa aagcttctga cgcaactaaa
    24961 attggaaaag aagatgaaga taattctaca gctacagacg ttacatttaa agatgatgca
    25021 aagatatctg tatcagttgg agatccaaaa atagatttag caaaatcatt tgcttttgat
    25081 gacacaactg gtaaactaga tggaatagta gaaaaagaaa atactgcaac atcacatgca
    25141 tatgtaagag tcataaatgc taaagagcaa acaatagact tagatgctag ttcatataaa
    25201 tcagctgaag atttagctaa agcttatgca tttgatgtaa atgagcttaa gactctttac
    25261 actgaaatag aagcatatca aaaagatagt aataataaaa ctgataaagt tcaaatagtt
    25321 gatggtaaat atcaaacaat actttatgct gaaggaaaaa gattaactac taaatcagca
    25381 actcaagctt ctaaattagc agatgaaaat tcaccactta agttagttat aaaagcagat
    25441 aagttaaaag atttaaagga ttatgttgaa gatttaagaa atgctaataa tggttactca
    25501 aatactgtta ctgtagcagg tgatgataga atagaaactg caatagaatt aagtagtaaa
    25561 tactataata attcagatga agacaatgct ataacagaag atgctgttaa taatgttgta
    25621 ctagttggat ctcaagcaat agttgatgga cttgttgcat cacctttagc ttcagagaag
    25681 aaagctcctt tattattaac ttcaaaagat aaattagatt caaatgtaaa atctgaaatt
    25741 aaaagagtta tgaatttaaa aactacaaca ggaataaaca attctaagaa agtttaccta
    25801 gctggtggag ttaattctat atctaaagaa gttgaaaatg aattgaaaga tatgggactt
    25861 aaagtaacaa gattatcagg agatgataga tatgctactt cattagaaat agctgatgaa
    25921 ataggtttag atgatgataa agcctttgta gtaggtggaa caggacttgc agatgctatg
    25981 agtatagctc cagttgcttc tcaattaaat caaaaaggtg atgctacacc aatagttgta
    26041 gttgatggaa aagctaaaga attaagctca gcagctgaag atttcttaga tgattcacaa
    26101 gttgatataa taggtggtaa aaatagtgtt tctaaagaca tggaagatgc tatagatgat
    26161 gctacaggaa aatctccaaa tagagttagt ggagatgata gacaagaaac taatgcagaa
    26221 gtattaaaag aatctgatta tttcccagat ggtgcagtaa attactttgt tgctaaagat
    26281 ggatctacaa aagaagatca attagttgat gcattagcag cagcaccagt agcagctaat
    26341 tttggaagaa cttataatat aaaagataat gatagttctg gaacagtttc tccagcacca
    26401 atcatattag caactgattc attatcttca gatcaaaatg ttgcaataag taaagcatta
    26461 ccttctggaa aatcaggaaa taatttagta caagttggtc aaggtatagc aaattcagta
    26521 ataaataaaa taaaagattt attagatatg taatataaat tttaaatata gagtaaaaaa
    26581 gattccttaa ataggaatct tttttatatt tgaaatttgt atcaaaaata aaagagagtc
    26641 tagatatcta gtctctcttt ttgtgagaaa tacttaaatg attaaaagat gtaattcatt
    26701 taagtatgat tattatacta taaataaaaa aagttgtcta ctattccaca tttttaaggt
    26761 ataataatag ttgtatgata aaaaaggagg taagaaatac atgtcagttt tagatacaat
    26821 acttgataaa gcagatgaac aagaaattaa gaagttgaat ttaatagtag ataaaataga
    26881 ggctttggaa gaagaaatac aaaacttatc tgatgatgaa ttgaaagaaa tgactaatgt
    26941 atttaggaat agattaaata atggagaaac tttagatgac atattaatgg aagcttttgc
    27001 agttgtaaga gaagtatcga aaagaaaatt aggaatgcgt caatataggg tacagttaat
    27061 tggtgggata gtaatacatc aaggtaaaat cgctgagatg aaaacaggtg aaggtaaaac
    27121 gttagttgaa gtagcaccag tatatctaaa tgctcttaca ggcaagggtg tacatgtaat
    27181 cacagtaaat gattatctgg cagaacgtga taaagaactt atgagaccag tttatgaatc
    27241 tcttggtatg acagtaggag taattatatc taaccaagac ccaaatataa gaaaacaaca
    27301 atataaatgt gatataactt atggtacaaa tagtgaattt ggatttgatt atttaagaga
    27361 taatatggtg ccagatttat cttataaagt acaaagagaa ctaaactttg ccatagtaga
    27421 tgaggtagac tcaatattaa tagatgaagc tagaactcca cttattattg caggagatgg
    27481 agatgaagat ttaaagcttt atgagttagc aaatagtttt ataaaaactg ttaaagaaga
    27541 agactttgag atggatagaa aagacaaaac tatagcatta acagcaagtg gtataagtaa
    27601 agctgagtca ttttttggta taacaaacct tactgatata aagaacatag aattatatca
    27661 tcatataaat caagctttaa gaggtcataa gcttatggaa aaagatgttg actatgttat
    27721 ttcaaatgga gaagtaatga tagttgatga atttacagga agagtaatgg atggaagaag
    27781 atatacagat ggacttcacc aagctataga agctaaagaa ggtgttgaaa taaaaaatga
    27841 atctaaaacc atggctacag ttacttatca aaatttcttt agattatatg aaaagctttc
    27901 tggtatgact ggtactgcaa agacagaaga aggggaattt gagtcaatct ataaattaaa
    27961 tgttgtccaa ataccaacta ataaaccagt gattagagct gatttgcatg ataaggtatt
    28021 taaaacagaa gaagaaaagt atagtgctgt tgtagaagaa ataataagga tacataagac
    28081 tagacagcca atacttgtag gaacagtttc tgttgaaaaa tctgagaagc tgtctaaaat
    28141 gcttaaaaaa caaggtatta agcatcaagt cttaaatgcc aaacaacatg ataaagaggc
    28201 cgagataatt tctaaagctg gtaaattaga tgctataacg attgctacaa atatggcagg
    28261 tagaggaacc gatatttctc taggtgcagg agataaagaa gaagagcaag aagttaaaaa
    28321 tttaggtgga ctttatgtta taggaacaga aagacacgaa tcaagaagaa ttgataatca
    28381 gcttagagga cgttctggtc gtcaaggaga tccaggtaca tcaagattct ttgtaagtct
    28441 tgaagatgat gtaataaagc tttatggtgg aaaaactata gagaaactta tgaagagaac
    28501 aagttcaaag gaaaatacgg ctattgaaag taaagcactt acaagagcta tagaaagagc
    28561 gcaaaaaggt gtagaaggta aaaattttga aataagaaaa aatgttctta aatatgatga
    28621 tactattaat gagcaaagaa aagttatata taatgaaaga aataaagtgt taaatgatga
    28681 agatatacaa gaagatattc aaaaaatggt taaagacatc atacaagaag caggagaaac
    28741 ttatttaatt ggaagaaaaa gagattatta tggatatttt aaacatttat atagtacatt
    28801 tatgccagca gatacattac taatacctgg tgtagataaa aaaagtgtcc aagagataat
    28861 tgatagcaca tatgaaattt caaaaagggt ttatgacttg aaaaagatga tgattggtat
    28921 tgataaggtt gcagagttag aaaaaacagt acttttaaaa gtggttgatc aatactggat
    28981 agaccatata gatgctatgg aacagttaag acagtatata ggtcttaaat cttatgctca
    29041 aaaagatcca tttaaggaat atgctttaga agggtatgac atgtttgaag ctttaaataa
    29101 aaatataagg gaagcaacag tgcaatactt atataaattt aactaaaaaa gttcatgtaa
    29161 tttttattaa atgaaaaata aagtattttg attctttata ttgtaattac aattaaataa
    29221 ttaaggaata aaaatgaaaa agaagctgaa aatcagcttc tttttctgtg tgagaaatac
    29281 ggaaaaaaga gatgcttgaa atttctttct tccatttaat attatactat aaagaagatg
    29341 aaaagtctat tagttataaa ctggattatt aaaaaaaatt acaattttgt tacttttttg
    29401 tatacataaa tattaaaaaa ataaaatata agaaaaagtt tgtatctttt ggttaattat
    29461 tacaataaat ctcatttatt gaaataatat caaatatata ttataattgg taaataagga
    29521 aaaaataata aaaatttgaa ttttttaggg ggaaaatacc atgaataaaa aaaatctttc
    29581 tgtaattatg gctgctgcaa tgataagtac atcagtagct ccagtttttg ctgcagaaac
    29641 tacacaggta aaaaaagaaa caataactaa gaaagaagct acagaattag tttcgaaagt
    29701 tagagattta atgtctcaaa agtatacagg aggttctcaa gttggacaac caatatatga
    29761 aataaaagtt ggtgagactt tatcaaaatt aaaaataata actaatatag atgaattaga
    29821 gaaattagta aatgctttgg gagaaaataa agaacttatt gtaactataa cagataaagg
    29881 gcatataaca aatagtgcaa atgaagtagt tgcagaagca attgaaaaat atgaaaattc
    29941 agcagacctt tccgctgagg ctaattctat aacagaaaaa gctaaaactg aaactaatgg
    30001 aatttataaa gttgcagatg taaaagcttc atatgatagt gctaaagata agttagttat
    30061 aactttaaga gataaaacag aaacagtaac ttctaaaact atatatgtag gtattggtga
    30121 tgaaaaagtt gatttaacag caaatccagt tgattcaact ggaataaatt tagacccttc
    30181 tgcagaagga tttagagtaa ataaaatcga taaattaggt gtagcaggag ctaaaaatat
    30241 tgatgatgtc caattagctg aaataactat aaaaaatagt gacctaaata cagtttcacc
    30301 acaagattta tatgatggat atagattgac tgttaaaggt aatatggtag caaatggtac
    30361 atcaaagtca attagtgata tttcagcaaa agattcagaa acaggaaaat ataaatttat
    30421 tattaagtat actgatgcat ctggaaaagc aacagagctt actgtagaga gtactaatga
    30481 aaaagattta aaagatgcca aagctgcatt agaaggtaat tcaaaggtta aattgatagc
    30541 tggagatgat agatatgcaa ctgcagtggc tatagcaaaa caaacaaaat atactgacaa
    30601 tgtagttata gttaattcaa ataaattagt tgacggatta gcagctacac cacttgctca
    30661 atctaaaaaa gcacctatat tgttagcatc tgataatgaa ataccaaaag taactttaga
    30721 ttatataaaa gatataatta agaaaagccc atcagctaaa atatatatag taggtggaga
    30781 atcagcagta tcaaatacag ctaaaaagca attagaatca gtaactaaga atgttgaaag
    30841 actagctgga gatgatagac atacgacttc tgtagcagta gcaaaagcta tgggttcttt
    30901 taaagataca tttgtagtag gtgcaaaagg ggaggctgat gctatgagta tagctgctaa
    30961 agctgctgaa cttaaggctc ctataatagt aaatggctgg aatgatcttt cagcagacgc
    31021 tatcaaattg atggatggaa aagagattgg tatagttggt ggctctaaca atgtatctag
    31081 ccaaattgaa aatcaacttg ccgatattga taaagataga aaagttcaaa gagttgaagg
    31141 agaaacaaga cacgatacta atgctaaagt tatagaaaca tattatggca aattagataa
    31201 actatatata gcaaaagatg gatatggaaa taatggtatg ctagtagatg cattagcagc
    31261 aggacctcta gcagcaggta aaggtccaat acttctagct aaaactgata taacagactc
    31321 acaaaagaat gcacttagta aaaaattaaa tcttggtgca gaagtaactc aaataggtaa
    31381 tggagttgaa ttgacagtaa tacaaaagat agctaaaata ctaggttggt aataacttat
    31441 actgtggaaa agattcctta attaatacag gaatcttttt ctataattat gctatttatt
    31501 gtaaattata acattttata aagtaggagg atgtagtagt ggtagatgca actttatttt
    31561 ttacaccaca tcaagatgat gaaaccttaa gtatgggaag tgctataatt gaacatgttg
    31621 aaaaaagtga tacacatgtc atattatgca cagatggtag taaatctata ataagaaaag
    31681 ttttggatga tggagggtca tgttcttatc atattaaaga tgttcataaa tattctttat
    31741 cagaaagtga gttttcaaaa gatagagatg aagaatttaa ggatagttgt gaagcaatgg
    31801 gtgtaaaaga aagtaatata catatagaag ataatagagc ccatgatggt gagctaagta
    31861 aggaaaaggc aagggaaata atacttaagt acttagaaga atatccagat gcaaaagtaa
    31921 aaactgttac tccatttaaa gctagtggaa tacatgaaga ccatagagca ttaggagaag
    31981 ctgcactaga gttatataaa gaaggcaaaa taaaagattt aaggttttat gtagaaccat
    32041 atgactataa ggattttaaa aaagttaatc caaatgtaga ggtatggaag gtattaccta
    32101 gtcaagaaga gaaattatta agtgcaatga atgcatataa aaaatggaat cctgaaagtg
    32161 gacattatgc tataggatat cattcagtaa aatctcattt tgatgagcta gctataaata
    32221 aaatacagta cgtacatgct ccataaaata ttataaaaga attaggaggt aaattttaat
    32281 gaaaatatca aaaaagatag tggcattatt gactataaca tttttaacta ttacattata
    32341 tggaaataca tctaatgcat ccacaaaata cacgttaaca ggttctggaa gacgggaaac
    32401 agcaataaaa ataagtcaag caggatggaa aaagtctgaa aaagctgtgc tagtaaatga
    32461 taattcaata gcagatgctt tatcagctac tccatttgct aaagcaaaag atgcgccaat
    32521 attattaact caaagtaata aattggatag tagaacaaaa gcagaattaa aaagacttgg
    32581 tgtgaaaaat gtatatttaa taggtggttc aattgcatta agttcagaga ttgaaaagca
    32641 gttaaatgca gaaaatataa attttgaaag aatatccgga aatagtagat atgatacttc
    32701 tttaaaatta gctgaaaagt taaataagga aaaatctata tctaaaatag tagtagtaaa
    32761 tggagaaaag ggtcttgctg atgcagtgag tgttggagct atagctgctc aagaaaacat
    32821 gccaataata ctttctgatt cggataatgg aactgaagta gctgataatt ttatagatag
    32881 taaagatata gaaaaatctt atgtaatagg tggtacatat tctatttcta attctgtaga
    32941 aagaagccta ccaaatgcaa caagaatagc aggtagtagt agaagtgaga caaatgcaaa
    33001 gattatagaa gagttttata aagatactga tataaaaaat atttatgtta caaaagatgg
    33061 tacaaggaat aagaatgatt taatagattc tttagcagtg ggtgtattag cagctaaaaa
    33121 tagttctcca atagtattag caggaaataa acttgatact gttcaaaaag atgttttaaa
    33181 tactaagatt atagataaag ttactcaaat tggtggttta ggtaatgaaa atgttgtaga
    33241 agatatacta gatatacaag aagaaactaa gtatactgtt gaaactattg atgagcttaa
    33301 tgtagttata aaaaaagcag atgcaaatga tattataaaa tttgtaccag aaaaggatag
    33361 aagtataaat agctcattta aaatagaaac agataaagct atagaggttg aattaaaagg
    33421 tgtttataag caatcaatta ctataaatat gccaaatggt aagattagta acttaggaga
    33481 aatcaatggt actacagaaa taaaaaatat aaagaataac tcatttataa ataagggaag
    33541 tatatttgac ttggatattt cttctaacaa tgaatgtaaa atagaaaatg aaagttctgg
    33601 tgaaatatgg cttataacta tatttcaaaa tgcaaaagga gtttatattg taaatgatgg
    33661 cgatataaca aaaatatcaa ataattcttc tgatgttata ataaagaatt ctggagagat
    33721 agatacagta actggtagta aagagcctgc cataagtggt aaaaagccaa gaataaatga
    33781 cactaaagtt gatgacacac ttgcaagagg tctttatgtt aaagctgatt catgctacaa
    33841 tcctgaaaaa gattatgtaa tggtgaccat attaagtgaa cctaaaagtt cagactatag
    33901 tatttattat agagtagtag aaaataaacc atctgctatg tatgtaggaa acaagattaa
    33961 tcctgcagat tgggatattg ttacaaaata taataaagaa tttattgaaa aagccaaaga
    34021 tggatcatac atagaagttg ttgaggtaaa ctctttaaca aataaagtct caagatgggg
    34081 aaaatctaat gtaactaatg atggtgttag ataatgtaat caataagcag ataattattg
    34141 tttagttatc tgcttattaa tttttaaaaa ttatcatttt actaaacaaa taatttaaaa
    34201 ctataacgac tatattagta aatattttta caataacatc atttacaaaa agcaaatcaa
    34261 tcattacata cataattaac atttcaacga caccagaaag tagcctaaaa ctaacaaaag
    34321 acaaaaattc cttaaataag aactttattt caattctttt actctcaaac acaaaaaact
    34381 tattagtaac ataagcaaat aaaacagcaa gtatccatgc caaagcattt gcaaccataa
    34441 aattaaataa aataactcta gtaaaaaata aatacgaaac tatatttaca agagtagtaa
    34501 atgctccaaa aaataaatat aatattgtct ctttatgttt tttaaaaatc aaatataacc
    34561 ctcctaaact aatcaaatat aactagcttt aaataaaatt aacacatttt agtataacac
    34621 atctattaat aaatcaatat atcttaaaat attataaaaa taaaactata atattctata
    34681 attaatatgt actcataatc catattttat caaaataaaa tatgacctta atttagaaat
    34741 ctgatataat aaaaattaaa tacatataag ggggtaaaca tgagaaagta caaatcaaaa
    34801 aaattgtcaa agctactagc attgttgaca gtttgctttt taatagtgtc aacaatacct
    34861 gtctcagcag aaaaccataa aactctagat ggagtagaaa ctgcagagta ttctgaaagc
    34921 tatcttcaat acctagaaga tgtcaaaaat ggagacacag caaaatataa tggagtaata
    34981 ccttttccac atgaaatgga aggtacaaca cttcgaaata agggtagaag tagtcttcca
    35041 tcagcatata aatcaagtgt agcatacaac ccaatgaatc ttggtcttac tacaccagca
    35101 aaaaatcaag gaagtcttaa tacatgctgg tctttttcag gtatgtcaac tttagaagca
    35161 tatcttaaat taaagggata tggaacgtat gacttatcag aagaacattt aagatggtgg
    35221 gcaactggtg gaaaatatgg atggaactta gatgatatgt caggtagttc aaatgtaaca
    35281 gccataggat atctgacagc atgggcaggt cctaagttag aaaaggacat accatataat
    35341 cttaaatctg aggcacaagg cgcaactaaa ccttcaaata tggatactgc acctactcaa
    35401 tttaatgtaa cagatgttgt tcgtcttaat aaagataagg aaactgtaaa aaatgctata
    35461 atgcaatatg gttcagtgac atcaggttat gcacattatt caacatattt taataaagat
    35521 gaaacagcat ataactgtac atataagaga gctccattaa atcacgctgt agcgatagta
    35581 ggatgggatg ataattattc aaaagataac tttgcatctg atgcaaaacc agaatcaaat
    35641 ggagcatggt tagtaaaaag tagttgggga gagtttaatt ctatgaaagg attcttctgg
    35701 atttcttatg aagataaaac tctactaaca gatacagata actacgcaat gaaatcagta
    35761 tcaaaaccag atagcgataa aaaaatgtac caacttgaat atgctggtct tagcaagata
    35821 atgtcaaata aagtaacagc agcaaatgta tttgatttta gcagagattc tgaaaaactt
    35881 gactctgtta tgtttgaaac agactctgta ggagcaaaat atgaagtata ttatgcacca
    35941 gtagcaaatg gagttcctca aaacaattca atgacaaaac ttgcaagtgg aacagtatca
    36001 tattctggat acataaatgt acctactaat tcttacagct taccaaaagg taaaggagca
    36061 atagtagtag ttatagacaa cacagcaaat cctaatagag aaaaatcaac tttagcatat
    36121 gaaactgata tagatggata ttatctatat gaggctaaag caaacttagg tgaaagctac
    36181 atacttcaaa acaataaatt tgaagatata aatacatata gtgaattttc tccttgtaat
    36241 tttgttataa aagctataac aaaaacatct tctggacaag ctacttcagg agaatcttta
    36301 actggagcag atagatatga aacagcagtt aaagttagtc aaaaaggatg gacttcttca
    36361 caaaatgcag tattagtaaa tggagacgca atagtagatg ctttaacagc tacaccattt
    36421 acagcagcaa tcgactctcc aattcttttg acaggaaaag ataacttaga ttcaaaaact
    36481 aaggcagagt tacaaagatt aggaactaaa aaagtttatc taataggtgg agaaaattct
    36541 ttaagcaaga atgtacaaac tcaacttagc aatatgggta tatcagtaga aagaatttca
    36601 ggtagtgata gatacaagac cagtatatct ctagctcaaa agttaaatag tataaaatct
    36661 gtttcacaag ttgcagtggc aaatggtgta aatggacttg cagatgcaat aagtgttggt
    36721 gcagcagctg ctgataacaa tatgccaata atacttacta atgaaaaaag tgagttgcaa
    36781 ggtgctgatg agtttttaaa ttcatctaaa ataactaagt cttatataat tggtggtaca
    36841 gctactttat catcaaattt agaaagtaag ctttcaaatc caacaagact tgcaggaagt
    36901 aatagaaatg aaactaatgc taagataata gataaattct accctagctc agatttgaaa
    36961 tatgcttttg ttgttaaaga tggttcaaag agtcaaggag acttgataga tggactagca
    37021 gtaggagcat tgggtgctaa aactgattca ccagtagttt tagttggaaa taagttagat
    37081 gaaagtcaaa aaaatgtact taagtctaag aaaatagaaa ctcctattag agttggtgga
    37141 aatggaaatg aaaatgcttt taatgaacta aatactcttt taggaaaata gtgaatggaa
    37201 agatagtaag gatatacatt ttattattaa aaaatattca atagaagttt ataaatataa
    37261 aataacaaaa aggggtgtct caaaatgaac tttttagttc atgaggcact cttttttgtt
    37321 gttttatatt tttatcattt aaataatgaa aaataggatt gtctatattt ttagatagtt
    37381 ttcttattat tgatgaaaaa tgtaataatt ttaaactgta aaatagtgta aagttatttt
    37441 ataatataaa tatagtaaga ttttaaacaa aataaggggg aataataatg aaagcaccaa
    37501 aaactatttt aacaatactg acaatagcgc ttactttaag tagcatttct ataataccat
    37561 catatgcact tacagaggaa aaattaatag gtaatggtag atatgaaact gctgtaaaga
    37621 taagtcaaaa ggcatacagt tctagttcta atgtagtgct agttaatgac aattcattag
    37681 ctgatgcact ttcagctaca ccatttgcaa aggctaaagg agcaccaata cttttgacag
    37741 aaagtgataa gctagatgat aggactga
//
LOCUS       DAGQVA010000036        37224 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.036, whole genome shotgun sequence.
ACCESSION   DAGQVA010000036 DAGQVA010000000
VERSION     DAGQVA010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.036"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..896)
                     /locus_tag="MIV85_001973"
     CDS             complement(<1..896)
                     /locus_tag="MIV85_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBY2961310.1"
                     /translation="MKLKHIAIIGSLFPILFSIVLFFGVLMSADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNVLLAIIQVESGGTAKDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQMQYDATQHIPLSQA
                     KAGELVFFHSTYNAGSYVTHVG"
     gene            complement(893..3085)
                     /locus_tag="MIV85_001974"
     CDS             complement(893..3085)
                     /locus_tag="MIV85_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBY2961311.1"
                     /translation="MKERIQSAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTSSGFSTSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFILSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPENEDGKTREEVVKTEIESNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYMAHRARRMERRLAGAVTAGGVAGAVAGSTVSNARTTRNNSAKDNRGNTSSSMGQR
                     AGSKVGAVLDTKNKVKDKANAMKETVKDIPTQTAYAVHSAKEKAKTSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHKKNIADKRMELQKAQEARQARKTDGSATTGATRPHERPVTASA
                     IPKTNVEKTQEVKRPATTSTSKAGEPVKTNSVKERPLSSGTSDGKIPQSAQTVHSKNV
                     EKVVSHETHQNYKAERTTKAQTVEQAKRTTEHTEKNRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="MIV85_001975"
     CDS             complement(3085..5535)
                     /locus_tag="MIV85_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2961312.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNLKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEHQLPKKKYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSADDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSETRGLLHVIDELRCEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGEILSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            complement(5522..5911)
                     /locus_tag="MIV85_001976"
     CDS             complement(5522..5911)
                     /locus_tag="MIV85_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2961313.1"
                     /translation="MKKIRSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPAFLTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLQKEIFNETITAVRSVSYVPD"
     gene            complement(6029..6532)
                     /locus_tag="MIV85_001977"
     CDS             complement(6029..6532)
                     /locus_tag="MIV85_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBY2961314.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIEIGEYVSIDELNEMYEMIEELPDYIVDCLDEFIGHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIATSR
                     GMCEIPY"
     gene            complement(6535..7038)
                     /locus_tag="MIV85_001978"
     CDS             complement(6535..7038)
                     /locus_tag="MIV85_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBY2961315.1"
                     /translation="MQETRVLVETKRTTGEETTSYWFDLPIEVAEFEEKLGVSTESQD
                     YRIIEKLLPYADEVHEHTSVYQLNELDYMYRQLSSDMQEEYTMLHTVYENLEALYICR
                     NVITLYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFETYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(6957..7253)
                     /locus_tag="MIV85_001979"
     CDS             complement(6957..7253)
                     /locus_tag="MIV85_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2961316.1"
                     /translation="MNDIFRDMQAKVGCENISDLPSYKRKVWHEMKQLNLADYEEKQL
                     EDFSKYVFGMSCQTLKDVMKQQKGREEQCRKQGYWWKRKEQLAKKQHHTGSTCR"
     gene            complement(7350..7952)
                     /locus_tag="MIV85_001980"
     CDS             complement(7350..7952)
                     /locus_tag="MIV85_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2961317.1"
                     /translation="MDKVVIYIHGKGGNAEESSHYKPLFSDCDVVGLNYTAQYPWEAK
                     EEFPSLFDLICKHYKSVQIVANSIGAYFAMNALSDKQIEKAYFISPIVNMEKLIADMM
                     YWANVTEDELRDKKEIKTTFGETLSWEYLCYVKENPTTWKIPTNILFGEKDNLTSYAT
                     ISEFTKQTNATLTVMRNGEHWFHTEEQMKFLDEWINKSAR"
     gene            complement(8037..8198)
                     /locus_tag="MIV85_001981"
     CDS             complement(8037..8198)
                     /locus_tag="MIV85_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961318.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALVAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="MIV85_001982"
     CDS             complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="MIV85_001982"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBY2961319.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNHILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11017..11151)
                     /locus_tag="MIV85_001983"
     CDS             complement(11017..11151)
                     /locus_tag="MIV85_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBY2961320.1"
                     /translation="MWELLKDLLLVSFGMGIGVVLMCILTVGKEADRCMEEIKEREDN
                     "
     gene            complement(11159..12358)
                     /locus_tag="MIV85_001984"
     CDS             complement(11159..12358)
                     /locus_tag="MIV85_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBY2961321.1"
                     /translation="MNETDFLTALKEKRCAYGVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPNNPMFLLFDYVRIRFPTMDIKHIIKDILKLNIGYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLLAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIRKCENEECISKFRSFKSYGSGELVKHNETDKYG
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTQPEPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHYQIIKQQTATVEE
                     MVANVKE"
     gene            complement(12560..13954)
                     /locus_tag="MIV85_001985"
     CDS             complement(12560..13954)
                     /locus_tag="MIV85_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2961322.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFSSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(14071..14556)
                     /locus_tag="MIV85_001986"
     CDS             complement(14071..14556)
                     /locus_tag="MIV85_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961323.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQAFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(14654..15037)
                     /locus_tag="MIV85_001987"
     CDS             complement(14654..15037)
                     /locus_tag="MIV85_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBY2961324.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQVGNPQNHAPQGQPKK"
     gene            complement(15052..15378)
                     /locus_tag="MIV85_001988"
     CDS             complement(15052..15378)
                     /locus_tag="MIV85_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBY2961325.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(15614..18658)
                     /locus_tag="MIV85_001989"
     CDS             complement(15614..18658)
                     /locus_tag="MIV85_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBY2961326.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTDNHNGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITNGNG
                     NYSIAGATYGVFSDKDCTKQIATLTTDDSGNTEVAEVKATTVYIKELSAPLGYKVDTT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKANPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTTAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAFLPL
                     GTLTVEETKSPTGYLLDGAYMQANGSEEQIKALYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETKDTKPQGSATLKDTAFDIISLNDNAVLVEGKIYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSKWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGMELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPMKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DGKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            19186..20193
                     /gene="asrA"
                     /locus_tag="MIV85_001990"
     CDS             19186..20193
                     /gene="asrA"
                     /locus_tag="MIV85_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBY2961327.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKDVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            20194..20985
                     /gene="asrB"
                     /locus_tag="MIV85_001991"
     CDS             20194..20985
                     /gene="asrB"
                     /locus_tag="MIV85_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBY2961328.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            20998..21969
                     /gene="asrC"
                     /locus_tag="MIV85_001992"
     CDS             20998..21969
                     /gene="asrC"
                     /locus_tag="MIV85_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBY2961329.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            22026..22802
                     /locus_tag="MIV85_001993"
     CDS             22026..22802
                     /locus_tag="MIV85_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBY2961330.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            23073..25091
                     /locus_tag="MIV85_001994"
     CDS             23073..25091
                     /locus_tag="MIV85_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBY2961331.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            25306..26163
                     /locus_tag="MIV85_001995"
     CDS             25306..26163
                     /locus_tag="MIV85_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2961332.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            26260..27129
                     /locus_tag="MIV85_001996"
     CDS             26260..27129
                     /locus_tag="MIV85_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2961333.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(27500..28132)
                     /locus_tag="MIV85_001997"
     CDS             complement(27500..28132)
                     /locus_tag="MIV85_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBY2961334.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(28204..28557)
                     /locus_tag="MIV85_001998"
     CDS             complement(28204..28557)
                     /locus_tag="MIV85_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBY2961335.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(28635..28838)
                     /locus_tag="MIV85_001999"
     CDS             complement(28635..28838)
                     /locus_tag="MIV85_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBY2961336.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            complement(29228..29458)
                     /locus_tag="MIV85_002000"
     CDS             complement(29228..29458)
                     /locus_tag="MIV85_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2961337.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(29460..29867)
                     /locus_tag="MIV85_002001"
     CDS             complement(29460..29867)
                     /locus_tag="MIV85_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2961338.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(30227..30676)
                     /locus_tag="MIV85_002002"
     CDS             complement(30227..30676)
                     /locus_tag="MIV85_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2961339.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(30690..31616)
                     /locus_tag="MIV85_002003"
     CDS             complement(30690..31616)
                     /locus_tag="MIV85_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961340.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(31741..32145)
                     /locus_tag="MIV85_002004"
                     /pseudo
     CDS             complement(31741..32145)
                     /locus_tag="MIV85_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            complement(32295..32915)
                     /locus_tag="MIV85_002005"
     CDS             complement(32295..32915)
                     /locus_tag="MIV85_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBY2961341.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(33014..34282)
                     /locus_tag="MIV85_002006"
                     /pseudo
     CDS             complement(33014..34282)
                     /locus_tag="MIV85_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            34374..35189
                     /locus_tag="MIV85_002007"
     CDS             34374..35189
                     /locus_tag="MIV85_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBY2961342.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            35861..36628
                     /locus_tag="MIV85_002008"
     CDS             35861..36628
                     /locus_tag="MIV85_002008"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBY2961343.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(36956..>37224)
                     /locus_tag="MIV85_002009"
     CDS             complement(36956..>37224)
                     /locus_tag="MIV85_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961344.1"
                     /translation="LDKESINKIYNRKIKIEREVNIFEDEDVIINKKVLKFPKSWTKN
                     MQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVIILYYIYNH"
BASE COUNT        11595 a         6603 c         6509 g        12517 t
ORIGIN      
        1 attcccacat gggtaacata cgaaccagcg ttataggttg aatggaaaaa gaccaactcc
       61 ccagcttttg cctgcgataa agggatatgc tgggttgcgt catattgcat ttgtgccgtt
      121 ctcggtaaag agataccagc ttttccataa caccattgcg tcagtcccga acagtcaaag
      181 gaagtgttgg gattgctacc gccatacaca tatttccagc cttgatattt caacgcttca
      241 ttcattacct tttgtgccag ttctcccgat acctgcggaa cagttaaata ctgattgact
      301 aattccacat aaaacatatt tccatagcca taccgccagc ccccattttt cgcaacggct
      361 atcgggttgg tgtaggttac ttttttaccg ccagatttct cacgggcaaa gctctctgca
      421 aggttaaaag tatgtttctt tccttttcct gccacatatc ccacatagcc accgccatag
      481 ttataggact gtatcgccac attcaaatca tttattcctt gatttttgca ggaagaaagc
      541 agggacgcaa aatatttaca cccctgcttg attgagcttt ctgtatctaa cgagttgggc
      601 ggtaaaccaa gactttctga actctgcatg acatcttttg ccgtaccgcc actttctact
      661 tgaatgatag ccagtaacac attcacatac tcagaaatac cgtattcttt agcgtacttt
      721 tccaccatag gctgatgttt caagacttct gcggataaat tcatacccgt aatgcccgaa
      781 gaaaagttgc tgttctcgtc gtcgctgtcc gcactcatca gtaccccaaa gaaaaggact
      841 atggaaaaga ggataggaaa cagactgcca atgatagcga tatgtttcaa tttcattttt
      901 tcttctgtcc tttcttcgtt acaaggttac ggttcttttc agtatgttct gttgtacgct
      961 ttgcttgttc aactgtttgt gcctttgtgg tacgttctgc tttgtaattc tggtgtgttt
     1021 catgcgatac cactttttct acatttttac tatgtactgt ctgtgccgat tgtggaattt
     1081 ttccgtcaga tgtacccgaa gataagggac gttctttcac actatttgtt ttgactggct
     1141 cgcctgcttt ggaagttgaa gttgtagcag gacgtttgac ttcctgtgtt ttctcaacat
     1201 ttgtttttgg aatggctgaa gctgtgactg gtcgctcatg gggacgggta gctcccgttg
     1261 tcgctgatcc gtccgtcttt cgtgcctgcc ttgcttcttg tgctttttga agttccatac
     1321 gcttgtcagc gatattcttc ttatgctgtt cctgcttttc caagcgtccc gactgtctgg
     1381 attgttgttc ctgcaccatg ccacgcttga agtccgatac acttgttttt gctttttcct
     1441 ttgcggaatg gacggcataa gcggtctgtg tcggtatatc cttgaccgtt tctttcatag
     1501 cgtttgcctt gtctttgacc ttattcttcg tatctaagac agcacccacc tttgaaccag
     1561 cacgttgtcc catgctggaa gatgtattcc ctcggttgtc ttttgctgaa ttattccttg
     1621 ttgtccttgc attagaaacc gtactgccag ccaccgcacc agcaacaccg ccagcggtaa
     1681 cagcaccagc aagccgtctt tccatacgcc tagccctatg tgccatataa agatacggtc
     1741 tgcggaaaat tcttcgtccc atgctttgac tgtcgttagc gttcaaagag aacatactca
     1801 ttaaatcgcc taacttcatg tagataccag cgaaacacac tatctgcaag aacgccacca
     1861 taaagaacgg gtagtctgtg gaaatgttat aaaacatact ggaaatgcta aatgccaccg
     1921 ttacaatgag cgtaattcct gcccttgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggatagtaa aaagctgata ggtaaaaaca
     2041 tggcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtgat acctaagttg aagaacaaga ggaagaacac catacctaaa cggtttacga
     2161 cttgcggtat cgtcagattg ttgttgtcgt tactttcgat ttctgttttc acgacttcct
     2221 ctctggtttt gccgtcctcg ttctctgggc ttgccgatac aagagcttct acacggtctg
     2281 tcccgatttc ctctgcgttg ctgttcccaa actgtaagag tagccacggc tgttccactt
     2341 gaatagagaa taggctgtcc cttatcaagt ccacgctgtc cttgccctcg ctgtcagagt
     2401 ttgggagcat gatttttgtt cccaagtcca aagaagcggt actgatgtcg cttgaaaatt
     2461 catttatctt tttgatgtag tcgggagcat aggcaataaa tgaagccgac aaaataaaca
     2521 ccacaacaaa gttgataacg gcgtgaagtg ccttgctggt ttctctttta atcagtcccg
     2581 tataggcaac atatagtccc accactaaga taatgagaag caggaaaccg acatagaagc
     2641 cagaggttga aaaaccgctt gaggtaacgc ctgcaagggt ctgtatgctc tgcccgatac
     2701 tgtctgccat atcattgatg aagtccagct tgtaggcttc ctgcactaca tagcccgtgg
     2761 cattacttaa atataaactg atagtccaga caaaattagt gatacagtac aaaccatatt
     2821 gtactgattt tccaatcccg tccagccagt tccacggcaa ccaagcccag ctattatcca
     2881 catagaagtc aagctgatag ttggaaagcg gatatttgga atatagattt tctgcgttta
     2941 tcgtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggagagtgc caccacgaac agagccattt tgagaaagtg gaaaatcttc ttttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtatag gcggtctggt
     3121 atcaaaggcg tgtagcagtt cttcaaagac ggggtgtatc tgtaccacgc cgacacgccc
     3181 gtataagtcc tgcaacaagc attgtccgtt ctccaaatca cgaagtcgct tctgattgtt
     3241 ttcgtcctct ttgtcgatac cgaaaaattc taaagtctgt tttatctcgt tgatgtcagt
     3301 agaacggaaa gcgaatttta agccgatatt gtttttcaga ctttcctttg acacgtcccc
     3361 agaagattgc gtaacgaaat acacacctgc ctgcatagct cgtccagcac gcaccagctt
     3421 gttagataaa atttcgcctt gtgccacatt taagaacgcc cacgcttcat caaggtctac
     3481 gattttgaag atagagcggt cgctgtggat aaaatctaag gcaaaggtac taatcacaat
     3541 cagcatggaa accgatagta attcaatggt cgtgtattcc tcaaaagtcg tgtccttatc
     3601 tggcagtaca aggtcggcta cttgaatgat attgagctga ttatctaaac tgatagcatt
     3661 ttccaccgtt ccgtctgaaa acagaagatg tgcaaaatca tagtctgtaa agctgtcgat
     3721 atggtctgcg atattgcgtg aaattgcggt atcttcacag cgtaactcgt ctatcacatg
     3781 aagcaagccc cttgtttcac tctgggtaac agaacgcacc gccttacgaa gtacggggaa
     3841 tttttcgccg tccctagagg aaataccagt taaaaaggtt agtatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaacgggtca agaagccctg cgttgtcctt
     3961 gtcgcttgtt aggtttacga tattgatttc atgggcgatt tctggaagtg tttctttcca
     4021 gtttccacgc tctgattttg ggtctaagat aaccgcttga ccgccaaaca aaacagaata
     4081 gtacacaagc aggttattac agaatgactt cccaccgcca agcgaaccaa caaaagcaga
     4141 agcaagggca tttgtaactg taccttttac gccttgactg gcaagggacg gttgcagata
     4201 tacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgtgtcgca ccaaaaccaa gcccagctaa gaagtctgat tttacatact gcacataatc
     4321 attgatatat cgcttgctgg ctggtagaaa ttcagaatga agccccagca tatccccagc
     4381 aggacgtact aacttcacat tcaaatcgtc ataaaaatct ttgacttcat cacaacggcg
     4441 tttcagttcg tccaaatcat cagcagacac acggataaca taagagagct tatacatact
     4501 ttcttttgtc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtctactac
     4561 atttgagctg gtttcacttc cagcttgata agcgtgatta tcaaggtctt tcagttcctt
     4621 tttcttgttg cggacggtcg ttaatgcttt tcggttttcc acgatttcta cattcatgct
     4681 cgtatcaacg ggaaaggtaa attgctgttg ctggaaatag aagatttcac tagacggaaa
     4741 atcaagctcg cctacaatcg cattgacggt aaaataggac acataacttt ccttgtcctc
     4801 atgttccaat cgtaaatatc gctggctttc ctcaatcaca caccttgtcg ggcggataag
     4861 gtcgtaatac ttgataagtg tttctttctt atactttttc tttggtagct ggtgctcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc ataagatacc caaagtcatt
     4981 gatttccaga cggcgaacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aagtcgttca tcagcgtgtg
     5101 gttcacttca tggagaaact ctttgaacgt cagccacgcc gattttttaa ggttcttcag
     5161 attgagctgt tcttccgtaa ccatgagttt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatcttct ggtaagcgac
     5281 ttcctttaat ttccccgtaa ccaatctttt tgactgctcc tgcatacttc ttatagagct
     5341 ttccgtggca atctgcaaag catgaatttt accctcacgg gactgtgcga ttagctgtcg
     5401 gaaactgtca tgcacgataa atttctgttc tgcggataag aaagaatagt tatacggtat
     5461 cagctcatag taggcgaaca cctcattgtc cttgttccag acaaggttgt tgtcaatata
     5521 tttaatcggg aacataactc acactcctta ctgccgtgat tgtttcgttg aatatttctt
     5581 tttgcagttt tacggctttt cctgcataag tgattttcgg tcgcaacgca taggttatct
     5641 gtgatttcaa aaagctgtat ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgaggaaagc aggaataccg aagtatttta aaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ctgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggcaag ttaaagtcat tgattgcata caagactttt tctacattcc
     5881 agatacccgt gtagcttcta atctttttca agttctttca actcctctca taagtttcta
     5941 aatggaaaag gacagccctg tttcagactg tcccttaaag agaaatacgc cgtcagtagc
     6001 aacaatgctt gtcgctgatc ttccagcgtt aatatggtat ctcgcacatt cctcggcttg
     6061 ttgcaatgaa gcaaccgccc atatccaaat ctcgcccgta tgcttcatag tcaatatagt
     6121 tctgcaagct agggggaata tcgccaagtg cctgcaattc atctatgtag taataggcaa
     6181 catctgtcat ggtttcacag tcgggataat agtaaatatc gtccttgtgt tccacgactt
     6241 cctccagcgt cccataatga ccaataaatt cgtccaaaca atccacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcatcaat ggaaacatac tccccaatct
     6361 caatcgggaa gttatcggta tcatggattg cgtattcttc atactgttca ttcaagccga
     6421 ttttttcttt cacatcttcc tcgtcaatag ggaaagtaaa ccaagcaccg actaaatagc
     6481 cctcattata cttgccaaga ttagcgatat aaactgccat atcatcaatc atacttactc
     6541 tggcaattca aagataccgt gttccgttac taaaaatttc ccgtgttcct gcaagtgtga
     6601 agcataggtt tcaaagtcaa aatagtattc ttgacagtcc tcggataaat gtttgaatgt
     6661 agggtcattc atcagctttt gccttgcaac atcaatcatg cttttacagt cgggataaag
     6721 cgtaattaca ttcctgcaaa tataaagtgc ttctaaattt tcatacaccg tatgaagcat
     6781 tgtatattct tcctgcatat cgcttgaaag ctggcgatac atataatcta attcattgag
     6841 ctggtacacg cttgtatgct catggacttc atcagcataa ggcaacaatt tttcaataat
     6901 gcggtaatct tgactttctg tactgacacc taacttttct tcaaactcgg caacctctat
     6961 cggcaggtcg aaccagtatg atgttgtttc ttcgccagtt gttcttttcg tttccaccag
     7021 tacccttgtt tcctgcattg ttcctcacgt cctttctgtt gtttcatcac atcttttaaa
     7081 gtctggcatg acataccaaa cacatatttt gaaaaatctt ctaactgttt ttcttcatag
     7141 tcggcaaggt tcagttgctt catttcatgc cacaccttac gcttgtaaga gggcaggtct
     7201 gaaatgtttt cacaaccaac ttttgcctgc atatctctaa aaatatcgtt cattacatca
     7261 ctccaatctg aaatttaggt aagaaaaaag cagtcaatcc taagactaac tgctttgtgt
     7321 gtatggatat gaagttgtca aactgggatt tatctggcag acttgtttat ccactcatca
     7381 agaaatttca tttgttcttc cgtgtgaaac caatgctctc cgtttctcat aacagtaagt
     7441 gttgcattag tttgttttgt aaattcagat atagttgcat aagaagtcaa gttatctttc
     7501 tcaccaaata aaatatttgt tggaattttc catgtagttg gattttcttt tacataacag
     7561 agatattccc atgagagtgt ttctccaaaa gttgttttaa tttctttttt atctcgaagt
     7621 tcatcttctg taacatttgc ccaatacatc atatctgcaa tcagtttttc catattcaca
     7681 ataggtgaaa taaaatatgc tttttctatt tgcttatctg ataaggcgtt catagcgaaa
     7741 taggcaccta tgctatttgc aactatttga acagatttgt aatgtttgca aatcaaatca
     7801 aaaagtgatg gaaattcttc ttttgcttcc catggatatt gtgcagtata gttgagtcca
     7861 accacatcac aatcactaaa aagaggtttg taatgtgaag actcctctgc atttccacct
     7921 ttaccatgta tataaataac tactttatcc ataatagttg tcctcctcaa cttcaaattt
     7981 gtcgctttct tcatatccac attatatcat tctcatatca gcaccacaat aaaattttac
     8041 gcaccgataa tcttattgaa cagctctaac agtacgtctt tcacaccgcc agcattgaat
     8101 accaatccaa cggcaacaag ggcaactacc aagaagccga taagtttaga aaactcacgt
     8161 ttgaacccta agtagatacc aataaccaca atcgccataa gcactaagct ctgggcgttg
     8221 cttaaaaacc atgtgtatat ggataggtaa gttcctgata ttataaatat ctcaaacttt
     8281 tccccccatt cacacggagc gtgcgacttt caccgcactc cgcgttccat cgtgtttata
     8341 ttgaaaagta tttatgtagt agacctatat caagtttaat tcttgattgc cagctaatac
     8401 tctatattta tttagtctta tgagctggac tttatttagc ttcaatagag ctatatattt
     8461 ttgtattgtt tcttctgttt tagcgtgtat tagacggtgt accgcctctt ttaccaaaat
     8521 atgattttta taatcgtcat ttccaccagc tccagttggt acaatatgat gacaatgtat
     8581 ttcattagct tgttgaaatt cttccagagt tatagcacat tttccatgtt gagcagaaaa
     8641 tagcgaaatt cgattgtctg cgtattctat tgtgcgattt tccaaagata atttcattaa
     8701 ctggtacatc agtaatttat caacacttag attggtgtgg ataaattttc ttccctctag
     8761 agtgtagcaa ttcgctaaat acacctttgc cattggtttt ctgtgttgga tatatccaac
     8821 agggaaaata ggttcgccct cgccagcaac ataccggagc attttagatt taccatatct
     8881 tgttgcctcc tttgtcgtaa gttgtctgcc tgtttttctc aatctgcccc ttttgtttgt
     8941 acctaatctg ttagtgaaga tagccattac agctctattc agtttcatac aatccagatt
     9001 tacattcgtt gcaatctgat aataattttg catacctaat accattgaat tataaagtct
     9061 tgtttcttct aattccgttt tcccttttga gggagaagca attttctttg cctgtgatac
     9121 cagcttgtct ttttggtttt tgaattgttt atcacttata tgtgatttaa caactaactt
     9181 ctttcttctc ggtatcattt taatcttgaa accaagaaag tcggagtatc tttttctaac
     9241 atttacaatt cttgtttttt cttgtgatac ttccaatttt aatcgttgtt caatccattg
     9301 agtgattgct attttggctt tttcagcact ttccttgtag cggcagaaaa ctctaaaatc
     9361 atctgcataa cgaaccatat acatttcctt taactttgtt ttcttcattt ctttgtaagc
     9421 gttgctttta catgggctac cgcttttatt gatatgaacc acatagtttt ttgtaacagg
     9481 attttcctgc cattggcttt ctacccaatg gtctaactca ttaagaacaa tgtttgctag
     9541 tagtggggat attattcccc cttgcggagt tcctttctct ggatatgtta ttgtaccgtt
     9601 agtcattttg attggagctt ttaatatcct ttttaaaatg aatatcaagt gcttgtcccg
     9661 tattcccata gcccatatct gttttatcag cttggaatgg ttcacgttgt caaagaaacc
     9721 cttaatatca aattcaatca cataatgtag ctggctgatt tgtaggcggt tataggttgc
     9781 ttttattgca ttttcaactg acctattagg tctgaaacca tagctgtttt cactaaattt
     9841 agcttcgcag attggttcta atacttgttt tatacattgt tgtataagcc tgtcccacat
     9901 acaaggaata cctagaggtc tggttttacc atttggtttt ggtatttctt ttcgcctcac
     9961 tggcttaggt cgatacccat gtggactgcc tgcaacaatg tatcttactt ttttgacaac
    10021 tgtttctgct ggcaatttgc caatatcttt aattattgta ccgtctgttc ctgctgtttt
    10081 actgcctgca tttgctttga tatttcgata tgccagtaat atattttctc tcgataggat
    10141 aatatccata agatgagtga aaatatctcc attcttactt ttggcatata aatcatcaaa
    10201 ggtgttttgc atttcgtaat attcagcgtg tcttaaatct tctacacaca atgtttcatt
    10261 tttattttta ggcataaggc ttcactcctt tgcttgaaat tgagtgagct tttttatctt
    10321 actcgtaatc cttattgaaa caacataata cttttctaat atatacacga cttgagggca
    10381 ttcctccatt ctcattacaa gaatttctta ggttcgccct ctgcttttca gcattagttc
    10441 aactgcttat tgttcttcgt cagtttattc tcttgatgag aacccaatac ctttcctcgt
    10501 tccgataatc ttatctatac atatatatcc ttaggtcact agctataagc ctgctggctt
    10561 gataccgcct gtaacgttat atggcatttc ataacctata ttcttacttt gccacaccag
    10621 ctacgatttc tcgtaccttt gcatttctac aaagttcaaa tttagacccg tacattcgct
    10681 gtttcgtcag ttccttatag aacattctaa ccatagatat tttatagacc cccgacctgt
    10741 tggatacgct acccgcctct ggatagtttt cgatagaaga tatatgttca tcaactatta
    10801 cggtatcttt cagccgtctt taccgagctt caaacattct gagtttcctc atacaatgct
    10861 tgtcggaggc tcagggcagg cgtttcagag cgttacttca tcattccacc tgtcagatta
    10921 tcagttctcc taataaccaa actttttcgt tcttttatta gtgccttagc ttttcactaa
    10981 ggaacgagtc gcacataaat tttgtccgaa attcatttaa ttgtcctctc tttctttgat
    11041 ttcttccata catctgtcag cttctttgcc gacagttaaa atgcacatca agactacacc
    11101 gatacccatt ccaaatgata ccagcaataa gtctttcaat aattcccaca ttttttcatc
    11161 actcctttac gttggcaacc atttcttcaa ccgtggctgt ctgttgcttg attatctggt
    11221 agtgtcgttc ggtcagtttt gcctgctttt caatcgtttc cagatactcc gtctgattgt
    11281 ccttgtctat ctgcttcaac atcttcaagg tcggtgcaac ctgcctttgt agccagttga
    11341 gtgtacgctc cagcgtgtaa ggttctggct gtgttgtcag ctttacgggc ggtcgcccct
    11401 cgccaatgaa ccaagcccag cgtacattgg ttttccagtc gctttttcgc ttgtctggtt
    11461 ctttatcagc gaagcggata tattgattga taatagaaaa tgctgtcagt tctgcgtcat
    11521 aatgtgtcag cagttccaca acagcataat aggcacgttc atttttcaaa cgtatctcaa
    11581 atctattttt tatggggact tcctcaatcg gtatgccaag tttggcgtac tgttcgtaat
    11641 tcttttcata acagcagaag tacacttcac ttgaaaatga accaatatac agcgtgtgtc
    11701 ccataccgta tttatccgtt tcattatgct ttaccagctc tccagaacca tagcttttga
    11761 aagaacggaa tttagaaata cattcctcat tctcgcattt tcgtatcagc tctggaatat
    11821 caagtaagcc cgttcggtca ttgattgcca aatcaagacg cttcattaca ccgccctcaa
    11881 ccaatgcgtc cgtgaagaag tcataccaac ttcgctcttg tgccagcaga tagctttcaa
    11941 actggcgaca gcctttgcct ttcagttcca gcaggacacc tttttcttcg tcctgcgata
    12001 catacacaaa cacatctccg atatggtaat gctcggtgta tttgtaatgt ccgtaatctt
    12061 cgtgaagcat atagccgatg ttgagcttca atatatcctt gatgatatgc tttatatcca
    12121 ttgtgggaaa acggatacgc acataatcaa acagcaggaa catgggattg ttgggattga
    12181 atttttccac cgcttctaaa agcgtatgtt tcatgtcctc ggtcagcgtt acctttcctg
    12241 cttcgatacg gctcaaatgt tcacggctga tatttgccat gattgcaagc cttgtctgcg
    12301 atacgccgta tgcacagcgt ttttctttca aggcggttaa aaaatcagtt tcattcagtt
    12361 gtcatacccc caatcgtgat aattttgtga tattgtgata atttcaaggc tttatcacaa
    12421 aaggcgaaat gtacgaaaaa cccttatttc atgcggtctt gcaaaggttt ttgtggaagt
    12481 ttccgccgta attgtgcccc tctgttagat aatgaggggc ttgtatctgc tggcgtggct
    12541 aacgccacac cagcaacggc tagtccgtgc cgtcgccttt cgcttcgcac gtcgccgtcc
    12601 cgtcctgcct tgcgtatgca agtgagccta tggtctgcaa aaaatcatgt ccttttggaa
    12661 ctaagggtgt gtaaaattca cttatgacgc ttgttcccac atcacaatag ccacgtccct
    12721 tgatacgctt ctggaaaaac tgttttttca catcagaact gaacagcata ccgtaaccta
    12781 attcgctgat acgccccaag ccaacacgga aattaaaatt atctctgata ccgtccgaga
    12841 aatattttgc gtctggacgc tggcaggcaa caataaggaa atatcctgct tgtcgtccta
    12901 acatgacgat tttctttagc tggctaagta ggctcacact ttcttttgtc cccagcattt
    12961 caaaaaacgc cacatattca tcaaagataa gaaagcaggg cggtaaacca agataggcat
    13021 agttttcgcc cgttttatag tctgggtgtc gcttcatttc ttcgcttctt tgtaccatgc
    13081 cctcataaaa ggcattgaca caatcaatca tttcttcttt ggtgtgatac acatttccca
    13141 ttaccgtacc taaatctgca aggtcagcgt tcttcgggtc taatatgtaa agaacagcgt
    13201 tcgtatgtaa cagagcttca ataagcgtca gcagaaaata cgttttaccg ccaccagtcc
    13261 caccagcaat cagagcgtga gggagtgcgt catattccca tacaagattt ttcatcagcc
    13321 taagacagcc gttttctgct ttcacttcat caatggtaat gcggttcgct atcatatcat
    13381 aaagcatggt gtattcgata taaccgtcat gtaacgtctt gtcggtcagc tcacaataca
    13441 agccactttc caatttatcc tctaaccgta agagctggtc ttgatatttt cctaatgtaa
    13501 tttcacagcg gatatgaagc agtccttttt ccatttgata ataaatcttt ggaaaccaga
    13561 tgattttttc ccttgatctg ctttgcaggt cagtaaaaaa accgctgtct tgtacggtgt
    13621 ctgcttcata ccacttgttt tccagtatca ttcgtgccag cttttgacgg tgcaggagct
    13681 tcttgaaact gtcataacag aagcggtaat acagaaaagc gaccaatgca caaacaccag
    13741 tcgctatcag tagggttatg aagttgtaag tggaaagcgt caaaccgttg tctaataagc
    13801 tgaaatgctc ccaatcggta cgcatgagct gtttcatatt cagtagcagg ataaccgcaa
    13861 tgaatacaaa cagaagcgtc cctatggaaa agtggtagac aaggttcttg tcgctggctc
    13921 tgatacggtg tcctttgttt aaaatcattt tcataaatca atcactcctt tctgggtacg
    13981 aaaaaagcag tcaatcctaa gactaactgc tttgtgtgta tggatatgaa gttgtcaaac
    14041 tgggatttat tgttcttaac ttttctgtcg ttataaagct gacttacgca cattaacctc
    14101 tgcacagacc agcccagcta tatgctccgc tgtttcattt gtcagtacaa agagcattcc
    14161 gtcattacgg cattttttat gtgtgtcgcc attcaaggca taaacaaaac cttttacaca
    14221 ggtatcacta caggcattag ggtcaatcag tctcttgcag tcacgagaag tagtcatttt
    14281 cttttgcata tcagcaggaa gcgaagcgat tatatcctca tactttccag cgttgtctcc
    14341 gtaaatccgt gcaaaaacac ctgtcttgcg aaacacccaa ttcattactg ttttcttctc
    14401 tagttggtat gaagcggtgt aaccgctttt tgcttccttt attacaaggt cacagccctg
    14461 ctcaataagt ttggtattaa gtttctcgac aaacgcttgg tgttctggcg cgattgccga
    14521 tagaaattct ttgaatgaac ctttttcttt tgccattatc tttttcctcc acaaatttca
    14581 atttatccgt ttcttcatac acatattata acagttgctt atatccgcta caatgaaaat
    14641 ctagtttgcc agcttatttc tttggttgcc cctgcggtgc atggttctgt ggattgccta
    14701 cttgaccgcc tttattcttc aagataatat cgtcagcctt gatataccag tccacattga
    14761 cacctcgata gctggcgttt gctaccgtat cggctacggg attgacaagc tctacctctg
    14821 cattatacgg atagtccttg acgggaatat cagcaggaat tgatacttgt atcatacgtt
    14881 cctgcacact acatttcaaa tcataggttc ttcgtgtgat ttcttcactt gttgaaccgt
    14941 cgtcattttc tgctcgcacc tcatgtctga gggcagagaa cttcaataca ccgaaagttt
    15001 tttccttgtc taatacaata ccgtttgcta atctcataat catttacccc cttacttgct
    15061 ttcctcggct ggcaacatat catcagccgt taagatatag tttgtgaacc ctcgtccttt
    15121 gaccgcttta ccgtctgcgg taatctttgg attgataagt tttactcgct gttctggttt
    15181 gaaatgcttt tcgcctgctt tcgctggaat ggttacgata atatcatcag ccctttgtac
    15241 gtcagagtac aagttgtagc ttcttgatac gggcgtaaag cgtccgttaa tgcgttgctg
    15301 ttcaatcttg ttttcgccag caaattccaa gtttccaaaa gtctgtgcca tgttcggcac
    15361 tacatatttt aattccatag tgttttacct cgtttctttc ttctttttta agtttgttga
    15421 ttgtgctttc ttattctggg aattagggaa ataccagtaa tcccccagat agtaaagggt
    15481 aaatcaatgc ttcgcaccct tgactatccg tgtgcttgca ggttgttggc agacaagcca
    15541 gaataagtaa acgtctgccg tttgacagct tcggcagaga gcgtgatttt tcttttctca
    15601 taccgttacc gccttatgat ttcttcattt tacggcgttt gtaaagatat gttccagcca
    15661 gtccaccagc agatgtaagc aacattacca gaaatgccat gacatttgtg ttgtcgcccg
    15721 ttttaggact gtctgttggt ctgctcggtt tttctggtgt tgttggcgtt tcgggtttct
    15781 ctgggacttc tggtttttcc ttaaaagtaa tcgtctgtcc ctcgtcctca atgtccttat
    15841 gctcagtaac ttttttcggc tcgtttggat tgcttaaatc atacaattct tcaaaagtta
    15901 caagctgttt gccgtcaaga gaagtagcgt caaaggtaaa ggtaacttcc actttcatag
    15961 tttcgctgtc agcgataaac gtataatcac tttccacacg ttttccattt ataagaagct
    16021 ctgcattttc ttctttcaac atctgccagc ccacaagttt atactttgta ccaacttcca
    16081 agccctctaa ggttacagta tcaatgattg ttacgtcttt tcctgcttca agctctttgt
    16141 taccgtcctt atcggtagca gttgtatgta ttttgatgat acgttctgta ataagtaccg
    16201 tctgcccgtc gtcctcaata tctttatgct ccgcaacttt catgggttcg tctggattgc
    16261 ttaagtcgta taattcctcg aatgttacca gatttttacc gccaagctcg gacgcattga
    16321 atgtataaga aatttccact ttcatttctt catcatcagc aacaaaggta taatcgcttt
    16381 ctacacgttt cccgtcaatg ataatctcgg cgttttcttc ctttaacatc tgccagcctt
    16441 ttaactgata cttagtgcct tttgtaagtc cgtctaattt gacagtatca acgattgtta
    16501 cctcttttcc tgcaaggatt gtcttttcgc cgtctttact ggttgctgtg gtatggatag
    16561 tgatttcctt ttcgtattca tcagtcaaag tccctaaatc aatcacaaga ttatttcttg
    16621 ataccacgat ttcaaatggt gggataagtt ccatgccttt gttgctgtca gagcgtaatt
    16681 cttcaataat gtaagtatcg taaggcaacg cacctttgct gtcgtctggt tcagaagttc
    16741 caaaccatac accgtcctcg cttgttttgc cagcgttggt attgtgcttg tgcgaagccc
    16801 attttgaaga agtggagaat tgcccattat cgtcagttac cacaacatga ctttcgcccg
    16861 ttgtcttgct tgtgatccta aagggaacat cagcaagacg cttgtgtgtg cctgcaccga
    16921 ttttcacgcc ctcaatatcc ccacgcttaa tctgattgta gatagagtgg gcttcgtctg
    16981 ttaagtccac gatttttccg ttttctgtga ttgtaaaatc aatcggcttc gcaccgtctg
    17041 tcaagtaacc gtttggagct tgtttctcaa cgatacggaa attcccgtaa ggcaaaaggt
    17101 cagcagaagt agaagcgata ccctcaatat ccgtatggat tgtttttaca acttcgtttt
    17161 tcttgtatat cttgccctca accaataccg cattatcatt taaggaaatg atgtcaaagg
    17221 cagtatcttt caaagtggca cttccttgtg gtttggtatc tttggtttct aaatctcgtt
    17281 tctgaatttt gacaccgcca cgaatgactt tatctgatac ggaaaactgg ttacttccag
    17341 ttaatacggc aaggtcgccg tcctcggtaa tctgcgtaag gtataaggct tttatctgtt
    17401 cttcactacc attcgcctgc atatatgcac cgtctagtaa gtagcccgtt ggcgatttcg
    17461 tttcttcgac cgttagtgta ccaagaggta aaaacgcttt tccgtcctgc atatagaagc
    17521 tatcgccaga taccttgtat gcgtctgcta attttgtgat gtaatgggtt gtcccgttac
    17581 tgtctgtttc agcggttgtc tttgtaaccc atgtacgagt agcttcggca ggaagattgt
    17641 ctttattgta gaagcctgca taatatttcc atgtaaactc cgccccctct aaagaagcgt
    17701 tcccttgtgg gttggctttc tgtgtttcca tgtcaatttt aaaaagctca atcaaagtat
    17761 cggtaacttt tggcgtatca gatactttca aagtcgctgt ctttccagct tcgactttta
    17821 aggaatacac cgtagtatca actttatacc ccaatggtgc agataattct ttgatatata
    17881 cggtagtagc tttgacttct gcaacctctg tatttccgct gtcgtcagtc gtaagggtag
    17941 caatctgttt ggtgcaatcc ttatcggaaa agacaccgta agtcgcacca gcgatagagt
    18001 aatttccgtt accgttagta atgctggtat tattggaagt cttttgaagt ttggcatttc
    18061 cgacatttaa cttcgcccag aattgcccta attcctgccc ctcgccagag tagatataac
    18121 cgccgcattc atagcgtcct ttgttttctt tcacaaaggc ttttgcacca gcaaacactt
    18181 catcttgtgt tgcctttggt atttcatcat aagaagctcg cacgttatca cattgccagc
    18241 ctaagtgaac actcaatctt tgccacacaa caagctgtct taaaaggtag gcgtgatttt
    18301 tgcttatccc attgtggttg tcggtgtatt gcttcacata ttcgatagat aaggcaacat
    18361 cacttatctg gtcggcactc atacgggagc ttgcgtcagc tctggtcttg tagccgttct
    18421 taaaatctgt gttaatatcg atacaataag cgtcctcgcc ctcaacggtc aaatgcccct
    18481 cgttaaaggt agaaccaatc gaaccgtcat tcattacttt ttcaacgata ccgacacgtt
    18541 cttcactttc cgtccagtat tgcttgcttt ctgcatggac aagtgtagtc ggtaaagcag
    18601 taacgacagt cgcaaaggca agtacgcccg tacacaatcg tttcaatatc tttttcataa
    18661 ttctaaatgc tcctttcatt ttgggtaata aaatagccgt ccataatgaa cggctggaaa
    18721 tagaaaagga acgtcaattt aggcgttcca tagtctatga aatattcaat ttttttcttg
    18781 cttcaatact gatgtgccgt accatatctt tgcatatcta ggaaaacttg cgtatcaagg
    18841 ctcattcatt ggtagtaaat tagtagtaaa ttgatgtgtt tgtttccttg aaaatgctga
    18901 tagatactat gttttagcgg ataatcaact ttttagtatg ttttttgcat aaaaattgag
    18961 tagatagtag ttttattgta cttaatgatt gtatttaagt gattagattt gaaattgaat
    19021 aatgtagata ataaaaaaat attaacagaa cttaataaac tccattaata tttttttatt
    19081 atttttgaaa ctgtgataat tatcacggaa gcatagaaaa taaagtgtta agatttaaac
    19141 aagatagtaa gtaagtaaaa ctaaaatata agaaaggtga taaaaatgaa actaaaatta
    19201 gattcatcta agttcaatga aggtctgaat tatctaaaaa aagactacaa gatatttgca
    19261 ccagttttaa taccatttaa aggtactttt tcagatactg atgttataag atacaaggag
    19321 gtaaacgctt ttgaagaaat ggaatttgct aagaaagcaa acttttcacc aaaagatgtt
    19381 gtacttccca taaatcaagt attgttttat tttactgaaa aagagtttaa ggaaagcgat
    19441 ttagacaaca agaaaatttt aattttctta agagcttgtg acataaatgg tataaaaaga
    19501 cttgatgaaa tatatctaaa taatggtgaa gaaaaagatt atttttataa aaatatcaga
    19561 gataaagtaa agtttgcact tgtagggtgt aaggaaagtt ttagaaactg tttttgtgtg
    19621 agcatggatt ctaacaaaac tgataattat tcaattggat taaatataga aggagataca
    19681 ctgtacttag atataaagga tagtgaattt gaagtattta atggagaagc aactgaattt
    19741 aatgttgatt atgtaactga taatttaata tctgtagatg tgccagagaa tattgattca
    19801 aatgaaatga taggaaattc aatatgggat gaatatgata caagatgtat aggatgtggt
    19861 agatgtaatt ttgtatgtcc aacatgttca tgttttacaa tgcaggatat tttctataag
    19921 gaaaacgaaa atgtaggtga gagaagaagg gtttgggctt cttgtcaagt agatggatat
    19981 acagatatag caggtggaaa ttcttttaga aaaaaacaag gcgaaagaat gagatttaaa
    20041 actatgcata aaatacatga ttttaaaaaa agattcggat atcatatgtg tgttggctgt
    20101 ggaagatgtg atgatgcctg tccgcaatac atatcatttt caaagtgtat agaaaaaata
    20161 aatgatttag taattagtaa ggaggaagta taaatgaacc catatatacc agtaagtgca
    20221 aaaatactag atatagttaa acatactgat aaagaatgga cttttagagt aaactgcaat
    20281 acaaaaggtg tattgcctgg aaagttttat gagatatcta tacctaaata cggtgaaagt
    20341 ccaatatcag tatcaggata tggagaggat tatattgact ttacaataag aaatgtagga
    20401 aaagtaacta gcgagttgtt taattataaa gaaggagatt ctttttttat aagaggtcct
    20461 tatggaaatg gatttgatgt atccctttat gaaggaagag aaattgtagt agtggcagga
    20521 ggaagtgcat tagcccctgt aagaggaata gttgaatatt tttataataa taaagaaaaa
    20581 tgcgaaaagt ttaaattaat agtaggattt aaatcaccaa aagatatttt atttgcagat
    20641 gatttaaaga gatggagtaa aaaacttgat attttagtta ctgtagatgg agcagaggaa
    20701 ggatatagtg gtaatgtagg attagtaaca aaatacatac cagaattgga tatgaaagat
    20761 ataaacaata cttctatagt tgtagttgga cctccaatga tgatgaaatt tacagtagaa
    20821 gaatttttaa aaagagattt agatgaaaag aacatttggg tttcttatga aagaaaaatg
    20881 tgttgtggaa taggtaaatg tggacattgt aaaatggatg atacttacat atgtttagat
    20941 ggaccagtat ttgattattc atatgctaaa aatcttattg attagggggt gaagtttgtg
    21001 ataagagatt taaataccaa aaaagtaatg aaaaatgctt atagaattac aaaaacaaaa
    21061 tatgagactt ctttaagagt tagagtacct ggaggtctta ttgaccctga gagtttagct
    21121 gtagtttcta aaattgcaag tgagtacggc aatggacagg tgcacataac tacaagacag
    21181 gggtttgaaa tattaggaat aaatatggaa gatatggaag aaataaataa aattatacaa
    21241 cctgttattg aaaaaatgaa tataaatcaa agtgagaaaa acgcgggtta tccagcagca
    21301 ggtacaagaa atatagcagc ttgtatagga aataaagtct gtccaaaggc tcaatataat
    21361 acaactgaat ttgctaaaag aatagaaaaa gctatatttc caaatgattt acattttaaa
    21421 gtggctttaa ctggttgtcc aaatgattgt ataaaagcta gaatgaatga ctttggaatt
    21481 attggtatgg ctttaccaat atatgaaaag gatagatgtg taaattgtgg agcatgtgta
    21541 aaaaaatgtt ctaagatatc tgttggagca ttaaaaacag aaaataataa ggtggtaaga
    21601 gataaagata agtgtatagg ctgtggagag tgtgtactaa attgcccaac aaatgcatgg
    21661 actagagatg agaaaaaata ctatagatta gctataatgg gtagaacagg aaagaaaaac
    21721 cctagactag cagaagattt tcttttatgg gtagatgagg acagcataat aaagataata
    21781 cttaatactt atagatatgt agaaaagtat atagataaag atgcaccagg aggaaaagaa
    21841 catataggat atataattga tagaacagga tttatggaat ttaaaaaatg ggcacttgaa
    21901 ggtgtagagc ttccagaaat aactaaaatg tacgaaaaca tatactggag tggaattaaa
    21961 tatctataaa ttgagtaaaa catatatttg aataaattaa aatttaatag aaggaagagg
    22021 gagttatgca taaagaaact ttggataaat taactaatgc agctataaat aagataaatt
    22081 tattaaacac aagtaaagta aaatatttgg tatcttctgc gtttgcagga ctttatgtag
    22141 gtataggtat acttttgata tttactattg gaggactttt gactgatgca ggttcaccta
    22201 tgactaagat agtaatgggg ttatcatttg caatagcact aagtttggtt ataatgacgg
    22261 gaacagagtt atttactgga aacaatatgg ttatgtctgc tggtatgtta aataaaggtg
    22321 taagtataaa agatacttct aaaatatggg catacagttg ggtaggtaat ttaatcggag
    22381 ctttggtttt aggcattata tttgtaggaa ctggtctagt agacaaagga cctgtagctg
    22441 aattttttgc aaatacagca gctagtaaag catccatgcc atttacagct cttttcttta
    22501 gagggatttt atgtaatatt ctagtatgtg tatcagtgtt gtgttcgttt agaactaata
    22561 gtgatactgc aaaaataatt atgatattct tatgtttatt tgcttttata acatcaggtt
    22621 ttgagcatag tgtagcaaat atgacaattt atagtgtttc attattttca ccaacaataa
    22681 gtacagttac tattggagga gctatttata atttagtagc tgtaacactt ggaaatattg
    22741 ttggaggagc tttatttatg ggtcttggaa cttatatatt aggtaaagaa aagcttaatt
    22801 aaatttattg tataaattat aactctcttg ataaatacat ttttagtatt gttgagagag
    22861 ttatttttat atttttgaaa aaatatttga aacaaaaaaa atatgggagc atacgaaaat
    22921 atatcggtta tatatataaa aaatacgttt atatatgaat tatatagttc taaatataaa
    22981 aaaagttaaa gtcctaccgt aaaaaagcgc attttgaata agataacaaa tatgataaaa
    23041 ttggtcttgt tgaaattttt aggggggata tgatgacaaa gaaactagta atatcaaaaa
    23101 caaagttgtt tatttttata atagcattta tttctatatt tatatattta tttggaagta
    23161 aaaatacact tataggtgta ggtatagtaa cagctatgct aacactcttg gaaagagatt
    23221 taactatttc tccaattaaa aatttactga agtatttagc aataaatata atcttaggaa
    23281 tactatcatt ttttgcagta caaaatatgt atttaggagt tttattaaat tttatagcat
    23341 tatttataat agggtatgta tttagttatg acttaaaaag agcagtatat gtaccctttg
    23401 gtctaatgta tatatttatg gtaagtatac ctgtaggaaa aagtgaattt cctatgagat
    23461 tgtcggcttt agctgttgga gcagttataa taatgattgc tcaatttgtt atgaatagaa
    23521 ataggatgaa aaatgtcgga gataaagaac tgatatctat atgtgatgaa ttattagaaa
    23581 aaattagcct tttaaaaaat actattaatg atgatagttc tataattaaa tctagtatga
    23641 gaaaaataga tagctgtaat tatagaataa attctatatc taaaaatttg aaaatggtta
    23701 tttttgataa tagaaaagat gacttttata tcagtattag aggtatagac ataatgaata
    23761 ttttattttc attagaaaga ataagtttaa tcctggaaag atacaaaaag gatagtaaag
    23821 aatttgaaga tgaagatata aaaaatattt tagaagaaag tagcataaat agtaaatcag
    23881 atgttttagt tgtagcaacg aaagaaataa actatattaa gatgtgttta gaaaataaag
    23941 ataccataac tgataaagag atattaggat ttagagatta tgttattgct caggatacta
    24001 aaaatataaa tttaaaagaa atttatagtg ttttagaaaa tttatatgag tttttagtag
    24061 attataaaaa agtaaaatca agagacgaaa agaaagctga aagaaaatca aagatacctc
    24121 atgaatttaa acgactatca atatataaga aaaactttaa tttaaattct ataagatttt
    24181 cttatgcagt aaagattgct ttagctacag ctgtagcggg ttttattatg gattatttcc
    24241 atttaagaga tggaagatgg ataatgttaa ctgtcttttc attaacacaa ccttacgcag
    24301 aaaattgtat acaaaggtct agaaaaagaa tagaaggtac atttatagga gctgtaatat
    24361 ttattgtatt attttcaata ataaaagata gtacattaag gtcgttaata gttcttttag
    24421 cagggtatat aaactcttat gtagttgatt atagaaaatt aatggtatgt gtaactgttt
    24481 cagctcttgg ttcagcagta gttatgggag acccaaatgt tttaacaata agcaggattt
    24541 catatgtagc attaggagca attattgcat taatagtaaa taagtttata ttaccatatg
    24601 atgctaaaac aggctatcaa catgttatag aaatgtataa aggaatagtt aaaaatataa
    24661 ttgatgaagt caataagtct atagaaaatg tagctgatgt ttactatata aaaaatttat
    24721 tattgatacc atcacttatt gaagatagac ttatgttgat aaatgctata tataaagata
    24781 aacatcaaga ggatttttta gaaaatcaga aattactaat aagtaatatg tataatctat
    24841 atataaatgt taataaaaat aaaataaaag atgaagatgt tgaaaaaata ttgagagata
    24901 ccaattatat ttcaaattac aatgtagata agtatgatga aggaagaagt gtaattttag
    24961 agagtattgt aaatactaaa agtctaggtg acaagataat atgtctaaac ttactgcaaa
    25021 ctctaaatgg tgtcaaagaa atgtatagaa taagtaatat aactaaagtt tcaataaaag
    25081 aagcagctta gatattaaat tatagaatag ccatatattt aaaataaagt atatggctat
    25141 ttgttttata aaatactaaa agaaaataat atataaaaaa caaaaaacat atatttatga
    25201 attttatatg aaaatagtta aaatattgat ttttttcatt ggttgaaaaa acaatttact
    25261 taggataaac tataatagta ttcaaatatt atgggggtta gatttatgag taaagatgta
    25321 aaggtaaagc gtaataagaa atatgataca tttagtataa ctatggaact tgagagacct
    25381 ttactttatg atgaggttga gaacaaagat gataaaaata ataatagaaa atttaacata
    25441 aagaataaga tatttaaggg aataggtata ctatttgtat tgattttgct tggctttttc
    25501 atatggataa ataaaacata tgaacctcaa aagctggcaa aagaagctct agtcagcaat
    25561 agtaaagttg aagtaactgt aaatgaaaac atttcattta caccaaaagg aagaaaagtt
    25621 tctaaaggtt taattttgta tccaggagct aaagtagaaa tagaatctta tgctccactt
    25681 gcaagaaaaa tagcagaaag tggatatgag gttgtaatcg taaagatgcc acttaatcta
    25741 gctatacttg gaactaataa ggcacagaaa gttatggatt cttacaacaa catagaacat
    25801 tgggtaatag gaggtcattc attaggagga gttgcagcat caaattttgc acgtgataat
    25861 aaattaattg aaggcgttgt atttttagct tcttatccaa tgggtgatga gttgaaagaa
    25921 ttaggaaaaa aagttatatc tatatggggg agcaaagatg gagtagtcaa ttttaaaagt
    25981 cttgtagaat caaaacaaaa acttcctgat gatacaactt atgttgagat tgaaggagga
    26041 aatcatgcac aatttggaga ttatggaaaa caaaagggag ataatgatgc tattataagt
    26101 caagaaaaac aacttaatat tactgccaat agtatcatta aatttttaaa gaatatatct
    26161 taaactaaaa tttaaaaaat ataattttat aagttattat ttaaagtaaa tattaataat
    26221 ataatagaat gaatatttta ttacaagggg gattttaata tggaatacga tatgccactt
    26281 tacagaccac caagtgaggc ttatagtctt ataatacaag tcacactagg atgttctcat
    26341 aacaaatgta cgttttgtag tatgtacaaa tctaaaaaat ttaaaataaa gccactagaa
    26401 gtaataaaaa atgaaattga tatatttaga agatattata agcatgtaga aagaatattc
    26461 ttagcagatg gagatgcatt gataatacca atggagaaat taagagatat tatcttatat
    26521 ataaaagaag tttttccaga gtgtgaaaga attactatgt acggctctcc taaatctata
    26581 gagaaaaaat ctgatgatga acttaaagaa ttaagaaaac ttggtgttaa aatgatttat
    26641 ctagggcttg aaagtggaag caatgaagta ttagaagata ttaagaaagg ttttagtagt
    26701 gaacaattaa taaaagttgg tagaaaagtt aaaaaaagtg ggattaaatt atcagccact
    26761 gtaatagcag gtcttggagg aactaaaaaa acacatcagc atgcagttga tacaggaaaa
    26821 atgttaggag caatttcacc agattatgtg ggtgtactta gtttaatggt agaacctaat
    26881 actgaacttt acgatttact taaggcagga gagtttacaa tactagagga taaggctgtg
    26941 ttacaagaaa ttaaagagat gataaagaat atagatgcta atgaaaaaat tgtatttaga
    27001 agtaatcatg catcaaatta tgctaattta aaaggtgtat tacctgatga taaacaacgt
    27061 ctaattgatg aaattgatta ctatctaagt aaccaaaagc taaaaagaga agaatataga
    27121 agactatagt ttttgatata tcaatctata ttgataggta aatactaaga ttatttagat
    27181 acaaaaaatc atgctacatt aatagttgct tactattgat gtagcatgat ttttttatta
    27241 aaaaacaaaa tggtatattc atatataata tatcaataat aatgaaaatg tgaactagtt
    27301 taatagaatt ttacctatta taataaaaac aggaatttaa ataataaaaa gtaaagtaac
    27361 tttttattaa gtaactttac tttttatttt atttaatgtt gtattaaatt tatatatatt
    27421 aaaataatat acaaattttg aaaaagctct tataaaatga ttattaaagt aaagtttaat
    27481 ataaataaat tataaaatat taaactaatt tatcaatatt tcctgattga atatgcttaa
    27541 tgtttgattg aattttttta tatggccaat cccaccattt aatttctaat aattttgaaa
    27601 ttgtatcatt attaaatctc ttttttataa tttttgcagg tactcctcca acaatagaat
    27661 acggtggaac gtcattagta actactgctc ttgttccaat aattgcacca tcaccaatat
    27721 ttacacctga cataattata gaatcataac ctatccacac atcatttcca attataatgt
    27781 tacccttatt gtcccaagcg tccgttatat ggttgatatc gagtttccat tcttcataaa
    27841 agatgggaaa agtatatgtg gattttgatt tcattgagtg atttccacta gtcattagaa
    27901 attttgcatt acatgctatt gagcaaaact taccaattat taatttatca ttgtttatag
    27961 ggtaatgata caatacattg tttttctcaa aatctcttgg gtcattataa aagtcattat
    28021 atattgtgta atctccaact tctatatttt cccttgttat tacattttta agatatacag
    28081 tttgataatc attacttctt ggatatacct tatttgaact tggaatagtc atatttaaat
    28141 ctctccttta atatatatta tgtttttgac tattccacta ctacaataca tctcttcaca
    28201 gaatcactcc ttgttaagaa tcttcataag ataatggcgt ccttttttag tgttaagtcg
    28261 gatattcttt cttagtccat tctttttagc gtataactga caaactgtca ttttcttacc
    28321 aatagtgtca atgctatcat caaggtcatt ttgtattgct ttttccttat cccttaatga
    28381 tatatcatca cgttttccct ttgggggttt atcagtaggt acaagtttcc aagagtaaac
    28441 aaattgtggt ttaccaaatg aatatacata cttatatgcg tatcttccat cttttctctg
    28501 gctctctcca gttcttaaaa ttctatcttt attatctcgt cttttttcag ttgacatgat
    28561 aagaagctcc tctcaataac cgaattgagc ttgatacgtc atatgaatat tataacatat
    28621 aaggctcaat ttcattagat aaagtcaagt gtatcaacga ttttctcaaa ttgttttctc
    28681 tttatttgaa tgcgattgct attcataatg acccagccag aatcaaggtt ttcatcagca
    28741 agtttacgta attttttctc tccaatacga aagtattttg acgcttcttc aatcgtcaag
    28801 gtatattttt cccaaatagg tacatcagta ttgttcatag aatgtatcac tcctttctat
    28861 gttcgtagtt cagaagtaga tagatggctt tggtaagctc cattggtatt ttaaccaatc
    28921 ccattcttat gggcagaacc gtgtcataca ggtgtatcat tatactgtgg tacaggttac
    28981 ggcaaaacaa ccgttccaaa ggttattcac aaatcactat atagtagctc tcttgattaa
    29041 ggtcatggcg tatagtattt gttggctatc tgtatcacaa acgtatctat ctactttatt
    29101 cagttgtcaa agaacagtcg gcattgattt gtctataaaa aatcacaata gcttatgggc
    29161 ttttatagac aaataattag tgattctcca tgtaccaaat agcttgatac atggagagag
    29221 ggcgagatta agacaaatta aatctcaaaa tagcagtgat tagttttgtt cctagcattc
    29281 gctttgtttc ttcttctaca tgaatatagg gatttccgta ttcatcaaat aaagttttct
    29341 gtgaaagacg aatgatatag tgttcaaaat gtttaagtat tccgtttatt gcatttacat
    29401 cgccatgtac agcaagtaaa ataattgtaa aaggtaatac ttctttagta ggtttcattt
    29461 caatgttcct ccatgagttc tttcaactct tttagtgcat ttgttttgtg ataatgtatg
    29521 gtattttctg ctaaatccat caatgttgct atgtcagcat ttgtcatgtt gagaaagaat
    29581 gaaagtagaa ttatatcttg ttttcttttt gtaagttttc cgattgcttg tgccattaat
    29641 acatcttcaa ttcgtatgtt gtagtcgtaa gaaaccatac agatgtagtt agaatcataa
    29701 tcatctaaaa tactcaattt acttaattct gcaagtgaca aagattcgag agataccaaa
    29761 taatcatttc tgcgtttatt ttcgtcataa atatctctag catagttacg caaaactgtt
    29821 ttacagaaac tgtcgaattg atgttcaatt gtcttttcat caaccataag atttcaccct
    29881 ctttccatcg caaggagtta aataaccttg cttactccta tcacggtggg agggcgttaa
    29941 atcttcgata aatttcaaaa aaaagagaaa aaaatacaca ctctgcctat agggcaaaaa
    30001 tgtgtattct ttaaaacgta tttaatttat attggttgta agccaccacc atattgatgt
    30061 atggaaatat gcattggcta gcttttcata aaaatacaaa gatgcataag aaattaatag
    30121 aggggaaaaa cttattctgt tattaaaaag taggttaatt ctaataaatg ctattgcggt
    30181 cgaattaaac tatatacatg gcaatcaatc atgtttctat tctttattat gaattgtgac
    30241 agtattcttc aatcttaaaa ccacattttt ccaatacttt acttgaccct ctattgtagg
    30301 aatatacatt agcatgaatt ttgttaaggt tgtatttttc aaaggcaatt ttgcatattt
    30361 cttttactgc atttgttgct atccctttgc cccaatagtt cctagcaagc cagtaaccta
    30421 attcagcatt tttattaata gaggtatctt cttcaaatgt taggctgata cttccaatag
    30481 ccctttcttg ataaaaaata gcatagctaa gttgtttaac atctggagtt gccaaacaaa
    30541 aactaacaaa atctctagcg ttttgctccc tataagggtg ggggaagttg tcacgaagat
    30601 tctttgcaat ttctttatca ttcgcaaact caactaaatc ggtaatataa gcataattcc
    30661 actctataag ttccattttt cttctccttt tatgaaacag ctacaagaaa tctttctaag
    30721 ccaataccac ttatcaaaca gcgttctttt ttatttccaa gcatttgata agtccagtca
    30781 acaaatccac cgtcaactat ttcaacggtt tcatttcctt gtttgaccga taatttgaaa
    30841 ttgatacctt tataataatt attatcaaca tcatcattat gaattgataa ctctatatta
    30901 ggaaaaataa gtttgatagt ttcaaccatt ctgtcgaaaa atccgtcatt atctttgtat
    30961 ccgtttcttt tgcgtagaat aatagagaaa cgaacatttt ctatttcact taatatatct
    31021 ttataatagt ttaagtgctt ttctaacaac attttttcac aagtgtaaga ccctgtatct
    31081 ataccagatg aaaccataca atataagcca aaatgtgaat ataaaccttt acctacaaaa
    31141 ttttgtgctc ttattaccct agcagtagta gccatgtgga taggtatggt attattttct
    31201 tcttttcttt ttaatttatc agcaataatt attgccaaca tatttgaggg gtctgcaagt
    31261 gtttctgtcc ctcgtagagc acttactaca ttatattgat ctacggagcc aaaaacgcta
    31321 cagctaccta atggagcaga gggagaaagc ataatcgtct tgatatccat attgaatgct
    31381 tttctcaata attttgactc caaagcatga atttcttctg gatctatacc gctagggata
    31441 gtaaatctat ttagttggta tgactttaga atatcagttg cagttaaagt atttgcttgt
    31501 ctatcaaaca cttctaatag aagtgagttc aaatctgatt ttgatagagc tgataactta
    31561 tcaactatat tcttatcccc aattttattt gtaattctac ttaaaatatc actcatagtt
    31621 atcctccata ctgttacttt caaaataatt atagaatggt tacaacaact aatctaggtc
    31681 atttgaccaa aaatgaaaaa acactgaata tttactattc aatatttttt tactttgggt
    31741 ttatttgatt aaatcttgaa aatactgtaa tgcaaccctt tcagcttcaa cctttcggac
    31801 aataggactt tgtgataatt cctctcttaa ctcaagatac aggttgatag tagcctgcaa
    31861 tgcattaaca cagcttttat attcatggtt agcaaccgtc ttttctaatg cttcaatata
    31921 ttggggtgcg tccaattcaa tttttctaac tccacgaggt aatttaccta agagaagctg
    31981 tattaatggg gcaagtactg attgtcttaa aaaagataaa aaatcaattg tttcaaatag
    32041 ttctctacgt ccaatcttag tgcaagcgta atgaacccaa atccaaaatc tatcttcaat
    32101 ccactgtaag tctggagttg ggaagtatgc ttctttttta gtataacacc tctcactttc
    32161 ttttattagc tatcaatcca acataattat gcataggagt attatataat gaaaaaataa
    32221 aaaaaaatag gtcacttgac ccgaaataaa aaagcattga ataattatta ttcaatactt
    32281 ttttgaaatt atacttatgt tgtaggaaga ttctttaata cctctcgctg attaattaca
    32341 ctaaatcttt tgttttcata agcaattaga tgttcttgta cacattcatt tatagcacga
    32401 ttaatgcttc taattggagc gtttacttcg ctagcaagct gttttttggt aagcagattt
    32461 aattcacttc tataatagtg taaggatata cacctcagaa gtcgttcttt aacacttaaa
    32521 gatgataatt cttcaattaa ttcagcattt acaactaatt tactagatat ttctcgaatc
    32581 agaaattttg tagcttcaaa atctcccctt aaccagttta aaaaatcatc tctatgaagt
    32641 ttatatacat tacaatctgt gaaagcgaca atttcaacgg gttttttccc atcattaaat
    32701 tgttccattt ctccaaaaaa actaccactt ctataaagat gaatagttga gatgtttcct
    32761 ttcacattta agatgaatgc ttctgcaata ccgtcaatca taagaattac atattcattt
    32821 tcttgctcag caaaaagaat agtctctttc tttttatacg tttttttaac aagcttcttt
    32881 ttaatatctt cattcataaa atcaattaaa tgcatattca tccctcctta ccaaatcttt
    32941 gattaaatta tatcatcttt caattagtta ggtaagatag taaaaatata tttacataga
    33001 aactattcca ttattatttt ccagttgtca tttttctgca aagtaagctc aaactgagaa
    33061 agctgttgac aatagaacta gtaggaatat atgagcgaac catttcagta ttcaactgtt
    33121 gtaggttttc agtcagataa ttcttcaaac gttcaattcg tttgtcctgt gaatcttgcg
    33181 atgctctaac cagtttcata gatagcgttt taccttgtgc cacctgcaaa aaagaccatg
    33241 cttcgtcaag gtcaactatc ttgaagctag agcggtcagt atgaataaag tctaatgcaa
    33301 aggtactaat aacaatcaac atagcaacac taagaagttc tattgttgta tattcttcaa
    33361 agctagtgtt ggcatctggc aatacgaggt cagcaacttg aataatattc agctgtttct
    33421 ccaagctgat agactgcttc acatttccgt caccaaacag tagatgtgca aaatcatagt
    33481 ctacaaaact ttcgatatgg tcggctatgc tgttactgat agaagtatct tcttttcgta
    33541 attcatcaat gacaagtaat aaccctcgct gttcactttg ggttacattg cggattgctt
    33601 ttctaagcac tgggaactta tcactgtcac gactggagat accagcaagg aatgttagga
    33661 tatcaatcgc taaactttca gaatcatttt tacggctcaa aatgacgtaa gggtcaagca
    33721 atcctttgtt ttcatcatta ctggttaaat tgacaatgtt tatctcatgg gctatttctg
    33781 gtagcgtttc tttccatttg ccgcgttctg ctttagggtc aactatgacc gcctgtccgc
    33841 cgaatagtac cgcatagtaa acaagcatat tgttactgaa taatttacca ccacccaatg
    33901 aaccgataaa cgcagacgct aacacattgg taatagaacc ctttacccat tgactagcaa
    33961 gggcaggttt tagatagaca ttctttccag tgtccagatt gtagccaaga tagatatcct
    34021 catgttcgcc aagggtttgt gtcgctccaa aaccaagtcc agccaaaaaa tccgaagtga
    34081 catattgaat ataatcattg atgtaacgtt tgctgacagg aataaattcg ccatgcaatc
    34141 ccaacatatc cccaaaggga cgcacgagct tgagtgataa gtcgtcgtaa aagtctttga
    34201 cttcatcaca acgccttttt agctcgtcaa gatcctttgt agatacacgg acaacatagc
    34261 taagtttata catagattct ttacagttaa aagtctgttt ttaaaaaaat gtataaatta
    34321 taaatcaaaa tatagatact atcaatgacc cactaggtgc aaaaagcatt gatatggtta
    34381 aattatcaga cgctaaaagc tgggctatcc gaatgagtga agatgggtgt gcttataaat
    34441 ccattgacaa ttataagcgc tcactgaaag cgtcgttttt catggcaatt caagacgact
    34501 gtattagaaa gaatccattt aattttcagt taagtgatgt tttggaagat acaacagaac
    34561 caaaaatcgc tctaacacca gaacaggaaa tgggcttatt atcctttatg gagagcgata
    34621 agacttattg taaatattat gatgatgttg ttatcctctt agaaacagga ctacgcattt
    34681 ctgaattatg cggtttgact ttagaattgg atatgaaaaa taaagccatt atggtagacc
    34741 atcaattgtt gagtgatact aagattggct attatgtaga agttccaaag accacacagg
    34801 gtaagcgaga aattccaatg actgaaagag cttatcaatc atttgaacgt atcgtggaac
    34861 ggcgtaagaa cgctaaagca gaaccaatca ttgttgatgg ttaccagaac ttcctatttc
    34921 ttaaacaaga tggattacca aaacaagcaa ctcattatca aagcatgtta agagcgttag
    34981 tcaagaagta taataagacc catgaggaca agctaccaaa gattacgcca cataccttta
    35041 ggcatacact ctgtacaaat atggctaaca aaggaatgag tcctaatata ttgcaatata
    35101 ttatggggca taaaaacatt actatgacgc ttggctatta tgcacatggt tcatttagtt
    35161 cttcgagagc tgaaatggaa cggttataat cctagtagta tgactagagt ttactactta
    35221 tttactactt ttgatggcat tcttatacgg ttaaatgcca acttatgcaa agtatcttcc
    35281 aaaaagaaaa tgccgatact ccttgtagat acaggatata tcgacattta ccaacttatg
    35341 aaaagataat caaatttaat ataagttttt caaataaaaa gataccaaat tctttttcga
    35401 gaatctatat aacattactt aagcttggtt ggggtataaa caattgagta gctacttttg
    35461 tatggtgttc aactttagtc aaaactctta agtaatgcaa atgatttaga ttcattaata
    35521 ttcaatctct tcataagtag tgaaattcga gttatttctg cataattata ctatgattta
    35581 tagattaatt ctattagcat ccagaataat attgtttata tgagtaaaat ttaaagaata
    35641 ttgtgaaaat tataggatgt taaaataaat ttaggtaaaa aagaagtgtt tgtatattat
    35701 agagtacctt ttctaaaata tgtgggattg ttttaagaat tagaataaaa attattttta
    35761 aattagtatt tttataatgt atagtatttt taatgtataa ttaaattgtg cagaaaatag
    35821 aatttaaagt cctatagaat ttctgattat ggaggagaat atgaaaagaa aagttcaagt
    35881 aaaaaatatt actattggag aaggtagacc taaaatttgt gtaccaatta ttgggaaaaa
    35941 taaaaaagat attataaaag aggctaaaga gttaaaagat gcatgtttgg atattataga
    36001 gtggcgagtt gatttttttg agaatgtaga aaatattaaa gaagttaagg aagttctcta
    36061 tgaattaaga agttatatac atgatatccc tttattattc acatttagaa gtgtagtaga
    36121 agggggagaa aaattaatat caagagatta ttatactact ttgaataaag aaatttctaa
    36181 tacaggttta gtagatttaa tagatgtaga gttatttatg ggagatgagg tcatagatga
    36241 agtagttaat tttgctcata aaaaagaagt gaaagtaatt atatctaatc atgattttaa
    36301 taaaactcca aaaaaagaag agattgtatc tcgtttatgt agaatgcagg aattgggcgc
    36361 agatttaccc aaaatagctg ttatgccgca aaatgaaaaa gatgtgttag tgctacttga
    36421 agctacaaat gaaatgttta aaatttatgc agatagacca ataataacaa tgtcaatgtc
    36481 aggaatgggt gttataagta gattgtgtgg tgaaatattt ggttctgcat tgacttttgg
    36541 agctgcaaaa agtgtttcag caccagggca aatatcattt aaagagttaa attcagtact
    36601 taatctatta cataagagta ttaattaaat taattatata gaaatattag acggtatttt
    36661 tgaagatata aattaaatat aaaaaacttt tcagatagta aaatttaaat tgggcaatta
    36721 tatctgaaaa gcaactattt agtgtgtatt ttgaaagtga tatagaaaat cttataaatc
    36781 aactatggca tatttaaaat atgccattaa aacctactag acattagatt atagatggta
    36841 tactagcatt tctattattt atagatagta agttttcata ataactgttt tatctaaagt
    36901 agaagatata tttgtattat gtatatttgt cattattttt ttgtaattat gtatattaat
    36961 ggttatatat gtaatataat attatcactc tattttttgt atattgtaca ttacaacatt
    37021 tatatctatc atcatcaatt acagtagaat gtatgggata cttattttca cttaaccaat
    37081 atttttgcat attctttgtc caagactttg gaaacttcaa tactttcttg tttattataa
    37141 catcctcatc ttcaaaaata ttaacttctc tttctatttt tatttttctg ttgtatatct
    37201 tattgataga ttctttgtcg agtt
//
LOCUS       DAGQVA010000037        36924 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.037, whole genome shotgun sequence.
ACCESSION   DAGQVA010000037 DAGQVA010000000
VERSION     DAGQVA010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.037"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(211..1461)
                     /locus_tag="MIV85_002010"
     CDS             complement(211..1461)
                     /locus_tag="MIV85_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBY2961345.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1494..2435)
                     /locus_tag="MIV85_002011"
     CDS             complement(1494..2435)
                     /locus_tag="MIV85_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBY2961346.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2675..3751)
                     /locus_tag="MIV85_002012"
     CDS             complement(2675..3751)
                     /locus_tag="MIV85_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBY2961347.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4124..4639)
                     /locus_tag="MIV85_002013"
     CDS             complement(4124..4639)
                     /locus_tag="MIV85_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBY2961348.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5002..6072)
                     /gene="leuB"
                     /locus_tag="MIV85_002014"
     CDS             complement(5002..6072)
                     /gene="leuB"
                     /locus_tag="MIV85_002014"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBY2961349.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(6079..6570)
                     /gene="leuD"
                     /locus_tag="MIV85_002015"
     CDS             complement(6079..6570)
                     /gene="leuD"
                     /locus_tag="MIV85_002015"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBY2961350.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6585..7862)
                     /gene="leuC"
                     /locus_tag="MIV85_002016"
     CDS             complement(6585..7862)
                     /gene="leuC"
                     /locus_tag="MIV85_002016"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBY2961351.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAKLKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAIIGKISKPSEII"
     gene            complement(7819..9561)
                     /gene="leuA"
                     /locus_tag="MIV85_002017"
     CDS             complement(7819..9561)
                     /gene="leuA"
                     /locus_tag="MIV85_002017"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBY2961352.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9685..9931)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10079..10525)
                     /locus_tag="MIV85_002018"
     CDS             complement(10079..10525)
                     /locus_tag="MIV85_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961353.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTNESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10546..11265)
                     /locus_tag="MIV85_002019"
     CDS             complement(10546..11265)
                     /locus_tag="MIV85_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBY2961354.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11383..12657)
                     /locus_tag="MIV85_002020"
     CDS             complement(11383..12657)
                     /locus_tag="MIV85_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBY2961355.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12857..14224)
                     /locus_tag="MIV85_002021"
     CDS             complement(12857..14224)
                     /locus_tag="MIV85_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2961356.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14474..14938)
                     /locus_tag="MIV85_002022"
     CDS             complement(14474..14938)
                     /locus_tag="MIV85_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBY2961357.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14943..15572)
                     /locus_tag="MIV85_002023"
     CDS             complement(14943..15572)
                     /locus_tag="MIV85_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBY2961358.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRIIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNKFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(15606..16493)
                     /locus_tag="MIV85_002024"
     CDS             complement(15606..16493)
                     /locus_tag="MIV85_002024"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBY2961359.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16522..17760)
                     /locus_tag="MIV85_002025"
     CDS             complement(16522..17760)
                     /locus_tag="MIV85_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961360.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(18144..19286)
                     /locus_tag="MIV85_002026"
     CDS             complement(18144..19286)
                     /locus_tag="MIV85_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBY2961361.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(19427..20293)
                     /locus_tag="MIV85_002027"
     CDS             complement(19427..20293)
                     /locus_tag="MIV85_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBY2961362.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(20627..22174)
                     /locus_tag="MIV85_002028"
     CDS             complement(20627..22174)
                     /locus_tag="MIV85_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBY2961363.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVLVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(22167..23303)
                     /locus_tag="MIV85_002029"
     CDS             complement(22167..23303)
                     /locus_tag="MIV85_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961364.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(23566..24663)
                     /gene="dinB"
                     /locus_tag="MIV85_002030"
     CDS             complement(23566..24663)
                     /gene="dinB"
                     /locus_tag="MIV85_002030"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBY2961365.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVDVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(25053..26558)
                     /locus_tag="MIV85_002031"
     CDS             complement(25053..26558)
                     /locus_tag="MIV85_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBY2961366.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(26820..27170)
                     /locus_tag="MIV85_002032"
     CDS             complement(26820..27170)
                     /locus_tag="MIV85_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961367.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(27393..27584)
                     /locus_tag="MIV85_002033"
     CDS             complement(27393..27584)
                     /locus_tag="MIV85_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961368.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(27702..28616)
                     /locus_tag="MIV85_002034"
     CDS             complement(27702..28616)
                     /locus_tag="MIV85_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2961369.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTNESYLKS
                     DKNDVSQNNIQSSTKNTAFKTTILSTGKSDCILVEIGNKVIMIDTGEDKNGKQIVDRL
                     KEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKA
                     DIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEE
                     RLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGVLKIL
                     ERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            complement(28750..30246)
                     /locus_tag="MIV85_002035"
     CDS             complement(28750..30246)
                     /locus_tag="MIV85_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBY2961370.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            complement(30526..32016)
                     /locus_tag="MIV85_002036"
     CDS             complement(30526..32016)
                     /locus_tag="MIV85_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBY2961371.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            32483..32683
                     /locus_tag="MIV85_002037"
     CDS             32483..32683
                     /locus_tag="MIV85_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBY2961372.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            complement(32849..33727)
                     /gene="speB"
                     /locus_tag="MIV85_002038"
     CDS             complement(32849..33727)
                     /gene="speB"
                     /locus_tag="MIV85_002038"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBY2961373.1"
                     /translation="MKNNFYHMNTFMSMNKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(33717..34568)
                     /gene="speE"
                     /locus_tag="MIV85_002039"
     CDS             complement(33717..34568)
                     /gene="speE"
                     /locus_tag="MIV85_002039"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBY2961374.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(34598..35011)
                     /gene="speD"
                     /locus_tag="MIV85_002040"
     CDS             complement(34598..35011)
                     /gene="speD"
                     /locus_tag="MIV85_002040"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBY2961375.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(35098..36573)
                     /locus_tag="MIV85_002041"
     CDS             complement(35098..36573)
                     /locus_tag="MIV85_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBY2961376.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
BASE COUNT        11910 a         6657 c         3825 g        14532 t
ORIGIN      
        1 ccttataaat atacaaatac aattatatga attttcatcc tcaattatag catagaatat
       61 gactatctat atcctaaaat tatccatttc taaaaaaaag gtaactatta ttaagaatat
      121 caacttatag aatttatatt ccacatacga ttttcaatca aaaaaacaag ggctaaaaag
      181 tgaattgtgc actttttagc cctttattaa ttattcattt atttcatgta agaatagacc
      241 acatcttact ttaggttcaa accatgttga cttagctggc attatcttat ttgcatctgc
      301 tactcttatt aaatcttcaa tactagtagg atacattgca aatgctactt tcatatcttc
      361 attaactctt ttttctaatt cttcaagacc tctaattcca ccgataaaat caattctttt
      421 atctactcta ggattatcaa ttcctaaaat agcatcaata acatagtctt gtaatataga
      481 aatgtctaat gagtcaacag ggtcttctat ttctaataaa tttttatttg ctttcatttt
      541 ataccactta tcacctaggt acattccgaa agttcctttt ttgtcaggtt tatatttttc
      601 ttttccttct atttcttcta gttcaaaatt ttcttttatt ttatttataa attcttcctc
      661 gcttaaacca tttaagtctt tgataaccct attataatcc aaaaccatta aattctcatc
      721 tggtgcaatc attgctatga agtaattaaa ttcttctttt ccagtataat ttggattttt
      781 agctctcatt tctttggcta cattttctgc tgaagctgtc ctatgatgac catctgcaat
      841 gtatagataa tctaattttt caaatttatc tactaggtta tctattatat catcattatc
      901 aatcttccat actgtatgct ctatcttgtc atctgttatg aaatcatata aaggttcatt
      961 attatccata aaatcattga ttatatcatc tatcaccctt tgatgtttgt aagttacaag
     1021 tatagttccc gtattagcat cacagtattt tatgtgttta gttctatcaa tttccttttc
     1081 tggtcgagtg tactcatgtt tttttattgt tccattcaag ctttcatcaa ctgatataca
     1141 tgctactata ccaacttgag ctctaccatc catgatttgt ttatatatat atatacactc
     1201 tttgtcatct tttactagaa tttcttgttt tcgaaactca tctaaatttt ctcgcgcttt
     1261 taaataaact ttttcatcat ataaatctat attttcatct aaatcaattt ctgatttatc
     1321 tatatgcaaa aatgaatatg gattcccttc tgcaattctt ctagcttctt tactattcat
     1381 aacatcgtaa ggaagtgctg ctactttatc tactatatat ttatttggtc taatcgcctt
     1441 aaatggttta atcgttgcca ttactaattt cctccctaat tatacaaaat attttataat
     1501 gctaccccta ttagattgtt gaagtcaaga aagaaatctt gaatcacatt tactatttcg
     1561 tctcctattc tttcttgagc ttctactgta gatgccccaa tatgaggtgt aggagaaact
     1621 cttggatgat ttactaagtc taaatttaat gtaggttctt gttcataaac atctatagca
     1681 gctgctgata atttaccttc atctaatgct tttagtaaat ctttttcatc aactaaaccg
     1741 cctcttgcac agtttattaa ataagcccct ttcttcatct tatttatttc tttttcagtt
     1801 attactgccc ccttattctt atcaaatggt atgtgtaaag ataagaaatc tgcattttct
     1861 aaaacttctt ccatatcaca gaatttataa ttgttaaagc cttgcgcctc acccattatg
     1921 tcagtatata taacattcat acctaataat tctgctctct ttgcaacttc ttttgcaatt
     1981 cttccaaaac ctataagtcc aagtgtcttt ccattaattt ctgtaccttt atactttttc
     2041 ttctcccatt ttccatctct catagttaca tttgcagtat ttatgaatct tgcaagaaca
     2101 aataattgac ctattgtaag ctctgcaaca gatatactgc ttgcatttgg agtattcata
     2161 acttttatgc cattagcttg agcatattta acatctatat tatccagacc tactccacct
     2221 cttactatca acttcaactt tttaccctct aatgctttat ctattacatc tttagtaact
     2281 ttagtagctg aacgtactac aagtacatca acatctttaa gtttatctcc taaaacatct
     2341 ttttcataaa actgctctat cacattaaaa tctaactctc tcaattttct cgctgcttct
     2401 ttctctattc catcagtaac taatatatta tacataacaa actcctccaa tttttattca
     2461 cttaattttt ccaattttta ttttttaaag tattttcatc aataaaaaac tttacttaat
     2521 ttaactttct gtttatataa ttttcaaaat atttttttat taaagtcata tcaaattttc
     2581 ctattgtttg ttaaaaattt aatatgtaat ttttataaaa tattatttat tatatattct
     2641 aaatttatct taaaacatac atatttttac aatattattt attaaaacct aatatatcat
     2701 caatattatc taataattct tgtacatctt cgacagtata gtcacccata tgtgaaattc
     2761 taaaagtttt ttcttttaaa tctccatagc catttgctat ttggaatcct cgttcttgta
     2821 attttgaatt taaatttgat acactaatac cttgagtatt ttctataaca gtaagtgtat
     2881 tggataagtg attttcattg gtaaaaattt ggaagtgttt tttagcccag tttctaacta
     2941 agtttgccat gtcttcatgt ctgttgaatc tgttatctag gccttcatct aatatattat
     3001 ctaattggaa atctaaagcg aacatgtgag aaagagatgg tgttgaaggg tattggtagt
     3061 ttttcttgat taagtattca tacattgcta acaaatcaag atatactcct ctaaaaggta
     3121 cttgcttagc tctatcgatt gctttttgag aaaatgtgca aatagacatt cctggtggta
     3181 atcccagtgc tttttgtact gatgttatac aaatatctat tccaatctta tcaacctcga
     3241 cttttattcc accggctgaa cttacagtat ctacacagta gattacatct tcatactttt
     3301 taacaacttc tccaatttct tctattggat ttcttattcc agttgaagtt tcattgtgag
     3361 ttacagttat taaatcgtat tctccggtag aaagcacctt atcaaccatt tctggcgttg
     3421 ttgcctctcc taattcaact ttaaatatat ccgctgggac attattagcc actgccattt
     3481 tgtaccatct atcaccaaag gatccacagg aaaatactgc tgcctttttg gatgtacagg
     3541 aacgaatgga gccttccatt aaaccagttc cggatgacgt ggataaaagt atcgtgttgt
     3601 ttgtatagaa tagtttttgc atcttttcac ttatactctt ttggagcata gatgcatctt
     3661 ttcctctatg tcctatcatt ggtgtagcca tcttttgcaa gacttcttct ttaacatcaa
     3721 taggaccagg aataaataat ttcttactca ttataattcc ccccttttta gtttgtaata
     3781 tggatagcgt ttttactgtc cttattttta ataactataa tatcaagctg aattaactat
     3841 gtcaacataa aatttatttt ttatatataa tttattttat atattttatg aaaacattca
     3901 ttttctacct tttcataagt ctgaattttc tgaattattc tctcaaaaaa aatatacttt
     3961 ttatctatat aaattaattt ttttagtatg taaatttgac gctattacga taaatctttt
     4021 tagtataact aatttatttt tatcttgtat ttttattgta tttttaaatt ttattttttc
     4081 taaatataaa atttatgttt taaaatgtaa aatttttatt taatcaaagt tcaatatatt
     4141 ccactttttc tttcgattct tcaaaaaacc attcttcatt agaaaaatca ccttctgcaa
     4201 tttgtccaat aggcattttc atatactttc cagttgctgt cactgctata tctccatttg
     4261 gtagaattat ttctcctgta ccttcaaata attttctgtt ttctttagtt attcttccaa
     4321 caacttttat agtagcatct gttggtactg gtttcttata tttcaactct aaagatactg
     4381 ttactcccca tatttggtca tcatttatac ttacagctct tccaatagtc tcatccaata
     4441 ttgcagcaga catacctcca tgaactctcc caggataact ttgatgccaa tcctttgtat
     4501 tacaaattga tacaagctct ccattttcaa gttcataaaa atctgcttta agtcctagct
     4561 cattttgtgt tccacaaact aaacaagatt tactactatt ttgcttcttc aaaactttat
     4621 actttgccaa aaaatccatc tcctaaccga cattagtagt cgcttaatat taaataattc
     4681 taaaatatat tatataatat taataaaatc cctgcaaact tctaataata aaaataggct
     4741 acttcaatat gataagttta atttaaagta ttattttcca aaaaataact ttatcaaaat
     4801 agaaactcaa agtagatata agcctctttt tcgttattaa aatagtaaaa atatatttta
     4861 cttaatataa aaaagagtgt ctcattaact aataaagttt attttgagac acccctcata
     4921 aaacaaatta tactacaata gatttttact aattctacaa gttatatatt taaattatat
     4981 tattcaaatt aaactataat tctaaatttc atttactatt aattcgccca ttgctcttgt
     5041 tcctacaaca tttcccacac cattatagat atcaatagtt ctataacctt tattgagtac
     5101 actttgtaca gcatcttcaa tacacttagc ttcttcttct aagttaaaac tatgtcttaa
     5161 catcatgctt acagatagaa tagtcgcaat tggatttaca atatcttttc cagctatatc
     5221 aggtgcactt ccatgtattg gttcatacat accaaaacta tcttctctaa gtgatgctga
     5281 tggtaacata cctatagaac ccgtaatcat agatgcttca tcagatatta tatctccaaa
     5341 tatattatta gtcactatta catcaaattg gctagggtct tttacaactt gcatagcagc
     5401 attatcaaca tacatatgtg acagttctac atcttcaaac tctttagcta agtcttccat
     5461 tatacttctc caaagtcttg aactctcaag cacatttgcc ttatctacac ttataagttt
     5521 tttatttcta tttctggcta tttcaaaagc tctcttacca attcttctta tttcattttc
     5581 gttatatatt tctacatcat aagcattttc gataccatca atgatttttc ttccacgttc
     5641 tccaaaataa atgccccctg ttaattccct tacaacaaca aaatcaatgc ctttctcaac
     5701 tatatccgtt ctaagtggtg aagcttcttt tatactttca tacattgtag ctggtcttaa
     5761 atttgcaaat aaacccaatg actctcttaa ttttaaaaga ccagactctg gtcttttatc
     5821 tcccttacat ttatcccact ttggtcctcc aacagcacca agcaatacag cttcgttttt
     5881 tcgacaagtt tcaacagttt tattaggtag aggttctcca gtttcatcaa tcgcgcatcc
     5941 tccagctaat acatattcac aatcgaatct atgattaaat ttacaacaaa ttttatttag
     6001 aacctttata ccttcatcta taatttccgg tccaacacca tcacctttta tgactgctat
     6061 attacaattc atacttcact accccctatt tgcttttatt gagttaatta agccttcatt
     6121 taatataata ttttgcataa actcaggaaa tggttctgct ttatattctt ttccttttgt
     6181 tatatttttt atcacacctg tagaaaaatc tacttctata ttatcccctt catctatgtt
     6241 attggcagct tcttcacatt caagtatagg aagccctata tttatagagt ttctaaaaaa
     6301 tattctagca aaagtagaag caatcacaca ggatactcca ctttctttta ttacaattgg
     6361 tgcatgttct cttgatgaac cacaaccaaa gtttttagtt gcaactataa tatctccttt
     6421 ttttacctta gaaataaatt tatcatcaat atcctccata caatgcgttg ctagttcttt
     6481 ataatcagct atatttaaat atctagctgg tattattaca tctgtatcta tattatcacc
     6541 gaatttaaaa acacttccat tggcaatcat aaattttacc tcccttaaat tatttctgat
     6601 ggttttgata tttttccaat tatagctgat gctgctgcta cagctgggct tgcaagatac
     6661 acctctgaat caacatgccc cattcttcct acgaaattcc tatttgttgt tgaaatggat
     6721 ttttctcctg ctgcaagtat acccatatgt ccccctagac atggaccaca agttggtgta
     6781 gaaactgctg ctcctgcctc tataaaagtg gtaatatacc ctttttcgat agcttcaaga
     6841 tatacttttt gagttccagg gaatatcata actctaactc catctgctac ttttttgcct
     6901 ttcattatct cagctactac ttcaaggtct gatattcttc catttgtaca agagcctatt
     6961 acaacttggt ctatctttat atccttatct atctcatcta ctgttctagt attttcagga
     7021 agatgaggaa aggctactgt ttcttttagt ttggctaaat ctatttcgta tacttcatca
     7081 tagactgcat cttcatctgc ttcatatata tttacatctt ttgtcatagt tgaacactta
     7141 tgtgaattta tatattccat agtcttatcg tctactggaa aaattccatt ttttgctcct
     7201 gcttctattg ccatattaca aatagtaaat ctatcatcca tagataagta ttctactcca
     7261 tctccacaaa attccattga cttgtaaagt gctccatcaa cacctatctc ccctattata
     7321 tgaagtatta tatctttacc acttatccat ttatttggtt tattcttcaa aacaaatttt
     7381 attgctccag gaaccttaaa ccaacatttt cctgtagcca tacctgctcc catatcagtt
     7441 gaacctacac cagtagaaaa tgctcctaat gctccatatg tgcaagtatg agagtcagca
     7501 cctataatta catctccagc agttactata cctttttcag gaagaagaac atgctctatt
     7561 cccatatctc ctacatcaaa aaaatttaca actccttttg attttgcgaa acttcttgta
     7621 aatttacatt gttctgcact ctttatatct ttattaggtg taaagtggtc taaaaccatc
     7681 actactttag tcttatcata aacatcttca attcctaatt tttcaaattc tctaatggct
     7741 actggtgatg ttatatcatt acctaaaact acatctaaat ctgcttcgat taattgccct
     7801 ttcttaactt catttaattt agcatgtttg gctaatattt tctgcgtcat agtcatcccc
     7861 attttttatt tcctcctcaa tataactttt atttattgca ttcataagtg cattaatagc
     7921 tgctgtattt atgttttccg atatacttac accaaaatag acttcattat tgtgctctat
     7981 tcctacataa gctacccctc ttgaatgtga cccttcctct aatgcatgtt cccagtaata
     8041 tctaaattta taatctttca tgccacattg ctttagtgca ttattaaatg aatctacagg
     8101 tccatttcct ataccaacaa tcctttgttc atttcccata taacttattc ttgcagtcat
     8161 ctcaatcata ttagtatcat tagaatcatc attttcatag tttaattcat ccattgattt
     8221 tattttatac ttcttaactt tataagggct ctcaacttca atatattctt tcttaaacaa
     8281 attaaatatt gcttcactac taagttcttc cccaattcta tcagattcca ttttgactac
     8341 atttccaaaa tcagaatgca tatttttagg tatcataaat ccataatctg tttccattat
     8401 ataaacagct cctccttttc cagattggct atttatcctt ataatttctt tgtattctct
     8461 tccaatatca tgagggtcta ttggtaaata tggaacttcc cagtaatcat tatctctgtt
     8521 tttcattgct atcatgcctt ttctaatagc atcttgatgt gaacctgaaa aagcacaatg
     8581 tacaagatta cctgcatatg gatgtctatc atgtaccata agttttgtac agtcttcata
     8641 tatacctatt atcttatcta tattgctaaa atctagctct gggtctattc cttgtgtata
     8701 aagattaagt cccacattta ctatatccat attcccagtt ctttcaccat ttccaaatag
     8761 tgttccttca agtctatcgg caccagccaa taatccaagt tcacttgcag ccgtacaagt
     8821 tcctctatca ttgtgagtat gcaaacttag tataatagaa tccctacaac ttatattttt
     8881 acaaaaccat tctatttggt ctgcatatac gtttggtgtt gccatttcaa ctgttgatgg
     8941 aagatttatt attacttttt tttgaggagt tggtttccaa acatctatca ctgcctcaca
     9001 tatttcaagt gcataatcca tctctgttcc tgtaaaactc tctggtgaat attcaaaagt
     9061 aaattctgtt tctggatatt tttttacttc ttcattaaat aattttgctc cttcaactgc
     9121 tatatctatt atttcttgtt tactcatatt aaaaaccaca tctctttgaa gaacagatgt
     9181 agagttatat aaatgtataa ttgctttttt acatcccctt attgattcaa atgttttttc
     9241 tataagatga gccctagatt gtgtaagtac ttgtatagtt acatcatctg gaatcatatt
     9301 ctcatctatt aattttctta aaaatgtata ctctgtattt gatgctgatg gaaatcctac
     9361 ctctatttct ttaaatcctg tatcaataag cattttgaac attctgactt tttcatttac
     9421 actcataggt gttggcagtg actgatttcc gtctcttaaa tcgacactac accaaattgg
     9481 agccttaaat atttcattat ctggccattt acgatttact atttgcattt tatcatattt
     9541 tttatacttt ccacacttca tgttatttcc ccctttttct gttttttgta ttcagtatac
     9601 ctcatatcga cgcaatcctg cacaattcat aaggataaat gtcaatttta tcattagaat
     9661 aaaaaaaacc tcatctctaa taaaattaga gacgaggttt tgctcgcggt accactctat
     9721 ttagctttct aaaaagctcc cttagtaata gccaatacaa taattataat gactatattt
     9781 cctataacgt ggaattactc cgattattct aagatttaaa tcttagaaaa cagctcctag
     9841 acaagttcag aactatcaac tactaaatca caccatcctt tagctctctg aaagtttcat
     9901 tgttcttact acttctattc atcacttttt taatcattta aattttctaa atattttgat
     9961 ttaatagtta ttatatacac attaaaatgt attgtcaaca caaaaaataa ttatctcaat
    10021 tttttatttt tgataagcaa ttctataaaa catgctaact attgaaaaca gtatgatatt
    10081 atgccttaaa ctttttcatc ttttcatcta tgatattcaa taattttttt tcatcttcca
    10141 aactcaatgc ccttaatcta attttataat tagattcgtt agtgtatata tttaatatat
    10201 tttttactac ttctattttt tctattatct tataattaaa cttttgactt tgtttagatt
    10261 ttatactgaa tatacattga ttatttatta atattgaatg attatcgaga gtaatatata
    10321 cttttccctc atatttattt gaaaaatcac gaccttgttt aaatagaaaa actgctgtta
    10381 ttatacataa aatatataat attgtcgttg aatatataaa aattgtagct aaaattataa
    10441 gtgctaaaac catatatata gtcattcctt ttttaaaata accattgtca taataattca
    10501 tatagataaa cttattttta ctcaaatttt ttcactccca agattctaaa aatttatatc
    10561 aaaaaattct ataatttcat cttcatgata atttatgact aattcatctg gaaaatctac
    10621 tgcttctaaa actttttctg cattttcaaa ttctcctata gaataacata tatgagagtc
    10681 agtaccaaga attactcttg caccatatgt tttacacaat gtcaacatat gacttacatt
    10741 ttcccaagta cccgttctat gagagtttga acttaatgat gaattattta tttctaaaag
    10801 gatattttta tctttagctt tttttactat aggttcataa tctaaaggat acctactgtc
    10861 atctggatgt ccaattattt ttaccttagg tttatccata acttttaaaa tagcatttgt
    10921 attttcttct tttgtaccag aagctataca aggtctatgc aaacttgcga ttatataatc
    10981 caaatgttgc aacatatctt cttgaacatc taaattacca ttataatcca ttatatttcc
    11041 ttctattcct ctaagaatct ttacgccttg cacttcacgt ggaagcaaat gcaaattata
    11101 aaaatagaat ggatgtggtc ctcctggcat attaggtcca tggtctgata ttcctaagta
    11161 ttttatattc ttcttactcg cctcttcgac attttccttg aaagtactat gtgcatgtcc
    11221 acttattaga gtgtgacaat gtacatccat aatagacttt ttcattaaat ttcctcctaa
    11281 tattttacat aaattcgtga aaatagctaa agggctattt caaaactaaa gctgtcataa
    11341 tagacagtgt aacgttttaa aacagcccca ttttcaatta ttttacactt ctaaatcttt
    11401 aaatttatct ttaaataatt ctccaatact tcctaaagat tcctctactt ctaggtattc
    11461 tgttatatcc tcttctggct ctctagttgc ttcttttatt gaaaccaaca ttctcttagt
    11521 ctttggttta aaatcaagaa tcttaacttt aacctcatct ccaatattaa caacattagt
    11581 aactttagcc actctagtat cactcaattc agatattggt aaatacgcat ctacaccttc
    11641 tttaatttga acaaaagccc ctttttctat tattctaaga actttagcat tgacaacatc
    11701 atcaatttgt acttcttttg ctattaaatc ccaagggtca ttatttatgt cttttaatgc
    11761 caaggcaatt tttttagtct ctttatttac atccaacaca taaacttcta cttcttgtcc
    11821 ctctgaaaca acatcttcaa cactttcaac tcttgtccaa gctaaattat ttatatgtgc
    11881 taatccttca atcccaccaa tatccacaaa tgcaccataa ggcattatct ttgtcacctt
    11941 accatctctt ttttgtccaa cttcaagaga attaaataag tcttctttag ctgctttgat
    12001 acgagctttt tcttcttctc tttcttgctt aattcttgct ctttcagctt ctttttctgc
    12061 cttaatttga gctcttcttt cttctctctc tttatttata cgctcttgta atacatctct
    12121 atgagatgct acaagtctat tttttctaac atccaattct tttatataaa cttctaagtt
    12181 aagaccaaca aatttagatg tatctgtaat aaattttgta tcaagttgag aaattggtat
    12241 aaaaaatgta tatgtattgt aattagcaaa tacaccttta tctatattct tttcaacatt
    12301 tacagttatt attctatgtt catcataagc cttttgtaac tcggcaaaat catttctttt
    12361 gtcaagttgt aatttagata aagttattgt accatctttt tgagatactt ttgttattac
    12421 agcagttatt tcatcaccta tgtggtatat atcttctata tattgatttt tttctatgtt
    12481 caattcactt ataggtatta ttccatcaaa cccatagtct aatcctaatt gtacttcatc
    12541 atttctcact gcagttattt ttccagttgt caattctcca actttcactt tgctgaatac
    12601 ttgttcttgc tggtcaagta attcttgcat tgttaaatca ttttccatta taaacatcct
    12661 ttcctcttat tgattatcat atctgtaaat attataccat taatattgca aatacttaca
    12721 tttttcttac tataattttt aaaataaatt caacttcata tatttataca ttatagaaaa
    12781 tatcttatta aattaaaata caaattctaa tttttatcta ataaaatatt ttcataaaaa
    12841 atttatattg tatatcttat tcttttattg ctttaggttt tgatagaaaa catttataaa
    12901 atataaagaa agaaattgct gttatagtag cagctgttat atctgcaact ggctctgcta
    12961 aaattactgc aaaaagtttt tcattaaaga atgttggaag tataaatatt aaaggtatta
    13021 aaagtacaat ctttctaagt agagctaaaa ccaaagatat tgttgctttt ccaagtgcta
    13081 aaaatgtctg ttgacaagct atttgaatcc caaacataaa agcaccagca aaatatattt
    13141 ttatactcca actagtcata ctaagtaact gcggattctt attaaatata ctaacaaaaa
    13201 atgcaggaaa tatcattaat aaaagccata aaatagtaga atatgtaaaa catgacaaca
    13261 aacacaactt aaatgtcttt tttactctat caagttgacc tgaaccataa ttataactta
    13321 ttattggttg tgctccttgt gtaaccccca tattaggaag cataagaatt tgcattatac
    13381 tgctcattat agccattgaa cctactgcta aatctcctcc atacatttgt aatttactat
    13441 ttaaggctat aagtactaaa ctttctgtag attgcattat aaatggagag attcccaaac
    13501 caagcactgg taagatgata cttgcttttg gtatcatata cttctttttt attttaagta
    13561 tacttttctt tccaaagaga aacataagta cccaaatagc agaaacgcct tgtgcaatta
    13621 tagtagctaa tgcagctcct tttacaccca tattaaagcc aaatataaaa atcgggtcaa
    13681 gtattatgtt tattaaagca cctatagcaa ctgtcatcat tccagttgta gcaaaccctt
    13741 gggtatttat aaaagtattc atacccattg aaatctgaac aaacactgta cctattaaat
    13801 aaatatttaa atagtccatt gaatatccaa ttgtagattc acttgctcca aacatccaaa
    13861 gtaaaggctc ttttccaatc ttaaaaccta tagtcaaaag tattgctaaa atcaccagta
    13921 cagaaaaact gttactcatt attttctctg cctcatcatt gttttgctca cccattttta
    13981 tagcagctaa tggacctcct cccataccga ttaaataact acatgcagtt attataatta
    14041 ttattggaaa tgccactcca acaccagcca tagcaacttc tccattttcc attctaccaa
    14101 taaaaatcct atcgactatg ttgtataaaa catttacaat ttgtgcgata atagcaggtg
    14161 tagcaagttt aaataataat ttacccacac tttcactacc taagttagtg tttgaatttt
    14221 ccattttaaa acctcctcaa tccaataatt aaaatgtatc actaaaattt tattctatat
    14281 aaaaatttca ttttattagc agacaaattt agagtacttt ccctacaagt aatactatac
    14341 tatatttctt ttgccatagt aaacatttta gaactaactg aagttaaata ctttatctca
    14401 ttttttattt attattaaaa atttttcaca catactcata aaaaaactat ccaagtatat
    14461 tacttagata gttttatatt atatgtaaag aaagagctga aactataacc cctgataaca
    14521 aattgccaag aaatactccc ataaaagcat cttttattct catttttaat atggaagcta
    14581 tagcagatgc agtccacgtt cctgtagttg gcagtggtat acctacaaat agtattatac
    14641 caattatcga aacacttttt aatttcttca ttcttgagtt tatttttcta tcaattacat
    14701 cagcaatccc tttaaatagt ttcttccctc ttaaaaattg taatacatgt ctgaatgtca
    14761 atatcaaggg aatcgatacc aatgtagaac ctattacact aaatacataa acccatatag
    14821 gatttaagcc cattgcaata cctataggaa tggctcccct caattctgtt acaggaacca
    14881 tagataaaat taatatgtgt aaatatccca aactattccc tcctattcta agtgacatta
    14941 agttatgaat ttatttgctc tataacctca ccatcctttt tactaactaa aaatgcattt
    15001 ttagtcaatg aaagcattgg taaatcactc ttagagtctg aatatgcata tgaattttca
    15061 taatcaatct ctatcccaag tttacctaat acagccttta ttctttttac tttttcaatt
    15121 cccttacagt tttctccaat gaatttattt ttatatcttg aattttcata aaaaaactcc
    15181 gtgcctataa cctcgtctgc aagaccataa tacttaaaat atttcatata tgcatatgga
    15241 gatgcagtta tcataattat aacattatct tcttctttat ttttgtaaat aacctttttc
    15301 atagattcgt taattttttt cattatgcaa tcatcaaaaa acttttttaa atcttcttca
    15361 ctaaaatcta ctattggata aaagattgcc tcttttgcct tcttcaatgg tattattcta
    15421 attaaataca taaatagaat aaaaataatg tatggtaact ttataatagt tttaaaggtt
    15481 ttatttttta aagagtaaat aaaaaaatct atcatgctat cagtatttat aacagtataa
    15541 tctacatcaa gtaataatac actttttttc ataagtattt ccccatccta tcactaaaaa
    15601 tatcactaaa aaatcaatat tattaaacat gtaattatcc ataagattac gtttattttt
    15661 aaagcattat cttttaagac aatatcagta ggattatttt catttgtagt gttaattata
    15721 taattatatc taagtacacc ataaactaca aatattgttg taaatatcat atgtggcttt
    15781 tctggattac ttgtagaata caatgcataa catacaattg tagaacttaa tataactatc
    15841 atcatttgat ttagattttc tatgtcataa tcttccaata tttttctatg ttcaactgca
    15901 tcatctctta gagtttctat ttctttttta cgttttccaa gagctaagta cagagataag
    15961 aaaaatgtac ataaaattat ccaatttgat aaactaacac ttatggctac acatcctgca
    16021 taaaccctaa gtataaaacc aagagatatt gaaaacacat ctaatagtat tatattcttt
    16081 agtttaagag aatataatat attgtttatc aaatagagac tgagaattat agaaagatta
    16141 aaactaacaa ctgttgataa acagactgaa attaaagcta atactacaaa tagtatatta
    16201 gcactttttt tgcttattct tccacttgcc actggtctat tacatttttt aggatgtttt
    16261 ttatctttat ccatgtctat agcatcattc agtgcatata ctgatgatga cattagacaa
    16321 aaacacacaa acgcaataaa cgtatttaaa aataaattta tatttagtat gttgtttgaa
    16381 aaaattatag ctgaaaatac aaagaaattc tttatatatt gctttattct cattaacttt
    16441 atataatctg aaattttagt aagaagcctt atacttgtat tggtctgttt cataaactta
    16501 ctaccctttc aatattattt tttaaacagg atatgatttt atccctatgt ttaaaatttc
    16561 tataaatcca ttgacattac tgattactat agtaaccaat aacagcgata gaaatatatt
    16621 atacatattc ttttcatttt ttctaagcgc tttcgtaaag taagccaata aaattataac
    16681 tgcaaaacta aaatttatag ccataatact tgaattgact agattatatc ctactatacc
    16741 atgtaaagtt agattgaata taattattcc catacatagc ttaggaactc ttttttctga
    16801 attttcaata actgataaaa cacaaaaaca taaagctaat aatgtaagaa ttactggtat
    16861 tgtagcaact tctccatttt gcaaaaataa ccctttttta atacttgctc caggaaaata
    16921 aaaaaccgaa tacaataatc tctctataat cattgcaatc ttttccaaaa ttggttctcc
    16981 acttataaat ttcgtatcat actgtattac atttccaagg ttcataaaac tctcataaga
    17041 ctttgttgaa actacacaaa tatatgccat taggataaat gtaattaaat gttttaacat
    17101 ttttcctatt tttaatttaa actcaaatat catattaaaa aaatacaaat atatattact
    17161 aatagttatt ccaaatagag gaatagctgc taattctact aaataagaat tttttccttt
    17221 catcttattt gcaataacta tgaaaaatat taatgaaaat tggctatata taaatctctc
    17281 tacatttaaa gtcataaata actgtggaaa agaaaatatc attatcatag taagtaaaat
    17341 taaagttaat ctctgcattt ttatcttttt aatatgatta aagactaaag ttattgacat
    17401 agcactagtt attatttgta gacaaattag tccaaaccca taggcactat taaaatctgt
    17461 tgtcccagga tttgctattg aagtacaaaa taggtatatt ggatatgcaa aaattgatat
    17521 aattgctgaa aacaatatgt gcttactatt gtcttgactt atagcaaata catttaaatt
    17581 gaataaaact cctgtatctg tatctaacaa tacatcataa gtattgttta aatcataaaa
    17641 tatagtagtc ttagaaaaaa atatcttagt tattattaag taagttatta caactaatat
    17701 aaacaaaaac atctcgtttt tatattttaa tattttactc atcaatatat caccatccat
    17761 tcattatata ggatttgctg acacctacaa tttattcctt atatttaata gccatcttca
    17821 taatgttctt acttgtttta ttgtaattga ataactcttt atttacaacc acaatattta
    17881 ctttattgat gttataatca gtcaagtatt gtttatataa catagattag tgttgtataa
    17941 aatgagaatt tgtaagcaat attaatgtaa aatatttgaa aaactttata taaaaatata
    18001 caatgttgct tatggaatta aactataaca aattaaagca taatttaagg agacaaaatt
    18061 ataatctgtc tccttaaata ttaaaactat attttaaaac attactaaat actatacaaa
    18121 tttcaaatat agtataaaat taattagact ttaacactat tagctccatc ttcttcccat
    18181 tttttaattt cttttaatct atctattata ggtaaatgct gagtacattc aacttcacat
    18241 tttccacaag atatacattc tttagctttt gccttactat tcattgtgta attccaatgt
    18301 cctaagccat aaactaactt tgtcatttct tcatcactct ttttaaacat ctgcttttca
    18361 ttataaaaaa gcatataggc tggggtatta ataccttttg gacatacttt acaataacca
    18421 caacctgtac atatttcgtt catattctta tttaatctag tctcaatatc atgtatatcc
    18481 tcatctgaat aaattctatt ttcgtctgca attttacatg catcatctat atcttgtttt
    18541 ttattaaacc ctatcaaaga tatacttatt tgtgaaattc ctatgttgaa tcttaaagct
    18601 gattctatag tactttcgcc atcttttgat agaaaagaaa gttctttatt atactttgga
    18661 atagttccac cacttaatgg gttcattgcc acaacaccat atccattatc aacagcatat
    18721 ttggcacctt ttagcctata tggaaagttt aatatattta ttcccatagt tacaccttca
    18781 aacttatttt cacttagaat atctataacc tcatctcctg gttgatgaga tgaaaatact
    18841 atatggtcta tcaatccttc ttctttacat ttcaataatc cttcatattg acctccaggt
    18901 ctcattgcta gttcgtaatg ttccatcttt ctaatattcc aaacatgata aaaatttatt
    18961 ttagatacgc ctaatcgttc tattgatttt tttacagcct ctatagcttt ttctgatgta
    19021 tcacatgctt ttggcttttc tttagttgat acataaaaat cggtcttacc ttcctttatc
    19081 atttgtctaa aggctagtcc aaatatatct tcacttctgt catcacaata ccctggtgct
    19141 gtatcaaagt aattaatacc tttttcatac gcatatttga ctaaatcagc attttcttga
    19201 ttactttttt ctaaatcaaa ccttaatcct ccatagccaa ctactgaaac cattttccct
    19261 gtctttccat attcaacgta tctcattgta aattcctcct tagatatatt aagacttaat
    19321 ttctttatag aaaatattat accataaata atttttataa attatttatg gtataatatt
    19381 ttttttataa attatatttt tttataactt gtattttata actaagttaa aaactataaa
    19441 aaggttcaat atggactatt acttgagcat tttcattaat ttcttcttgt atttgtttct
    19501 caattttatg tgttaaatca tgagattgct ctacgcttat aaatgggtct accattacat
    19561 gcatgtcaat ataaatagaa cttttgctac ctctacttct gatattgtga acatccctta
    19621 cctcattaaa ttcaaacaca atttctttta tataatcctc atctacagcc actctatcga
    19681 ccaaaattcc aatagatggc ctaaatattc cataagccga ataaattatg aatgcagaaa
    19741 taataatagg aactatagat tctattatta ctggaaatcc taacttaaca ccaactaaag
    19801 taaccaatac acctagagac acaaatatat cacttcttgt atgcaatgaa tccgaaatca
    19861 aaacataact atttagttta gtcccaattc tatattcata catgcataca aaaatattta
    19921 taaaaagtgt aataattaaa gcaattaaac tttctatagt tatagcaggt acaactggat
    19981 tagctattct taacactgca ctaagaatta tcttaattgc tataacaaac aacataccac
    20041 ttataaataa actggttata atttcaaact ttttatgtcc ataaggatga tttttatctt
    20101 ttggtttaga tgcaaagaaa atacctataa gccccactat attagatgct ccatctgaca
    20161 aagaatgaaa tccgtctgct gtcatactat agctttttat ttgattacca ataatgattt
    20221 ttaataatgc tactgcaaaa ttagcaaata aaattatcca caatacttgc ttcactttct
    20281 tatagttatc cataacaaat tccccctccc ttcgattcaa taaagaaagc tatctatcaa
    20341 tatcaatcaa ccagacaata aaatcgtata taagcacatt tactatattt atattcaaaa
    20401 ttggttgtac ttgttcattc tatttgaaac ttaattataa ataaaaatcg taggtatggt
    20461 tttggtatac ataaaaataa gagactgtct caaaataaag ataatcttct tttttattgt
    20521 tgaaatgata aaatatattt gatttcatat aaaaaagagt gcctcatgaa ctaaaaagtt
    20581 cattttgaga cactccctta aatttttgat ataaactatt aattttttat actaagcctt
    20641 ctttaactaa gaatgaatga gcaacttctt ctggtgattt accaagttca tccacttgat
    20701 agttaagttc tctcatagtt tcttcattta tttttcctga aagcatattc ataacttttt
    20761 ctaactcagg atatttcttc aaagtatctt ctcttactaa tggtgctgca taatatggta
    20821 caaagaaatt tttatcgtcc tctaatatct taagattaaa ctttttaata agaccatcag
    20881 ttaaaaatgc atctataacc tgagattcat tattatctaa agctgtatat cttaaacttc
    20941 cattcattgc ttttacatct ttgaatttta aaccataatc tctagaaagc cctacaagac
    21001 catcttctct attttcaaac tccaaagttg gtgagaatgt aaattcttta ccatatttag
    21061 tcaaatcaga aatagtattt attccatact tttcagcagt ttcaggcatc atagctaatg
    21121 tgtaagtatt attaaatcca agagggtcaa gtaaagttaa ctgattttct ttttccatag
    21181 tatcttttac aacattatat gcttcatcag catctttaat cggagcatgt ttcattacat
    21241 ttaccaaaag tgtacctgta tagtcaacat acatgtctaa ctcaccagat ttaattgcat
    21301 taaacgcaac agatgaacca cctagattta aattcttctt aactttaaga ttcgtatttt
    21361 tttctactaa ttcagcataa acattgccaa gtataagttg ttctgtataa tctttagaac
    21421 caatagttat tgtatctttt ttacttgaaa aactagaact aaaaacaacg aacaacattg
    21481 aaacaacaag cactacagat attactttaa gtgctatata attcttctta ggtgcttttg
    21541 gatttaatcc ttttggagta actgcaactt caattttact aaataaataa tcaactaaca
    21601 gtgcaattat acatgatggg attgcccctg ctaaaatcat attattattt acagtttgaa
    21661 cccctgaaaa tactaaatat cccaaaccac cagcacctat aaatgctgca agagtcatca
    21721 aaccaacagc tgtaactgca gatattctaa ctccacccat tattatagga agcgctaaag
    21781 gaaattgtat tttaaataat gtctgatttc ttgtaagacc aataccttta gctgattcta
    21841 atactactgg gtcaatactt gttataccta tatacgtatt ttttacaatt ggtagtaatg
    21901 aataaaccac taccataaat atggctggtt tacttcctat accaagtata ggtacaagaa
    21961 gacccaaaag tgccatagac ggaactgctt ggactaagtt tacaaatcca agtacaaact
    22021 ttctaagaga tgagattctt gaaataatta ttccaagagg aacaccaact attatagcta
    22081 ttaaaataga tgtaacagtt agactcatat gttgtattaa aagctctata atcttatctt
    22141 tttgtaatag tataaagtta aaaaaattag ccaagaacac tcacctccat ttctaagaat
    22201 tgttcactta aaacagaaag taaactactt ctagtaataa gccctaccag tttattttca
    22261 tcagaaataa ccggaatata tccaaccgaa ttacgattca ttacatttag tatttctact
    22321 aaattatcac cttcatttac atgcaaaggc tcacttgaca taatatcagc aagtaatatt
    22381 gacttatcat caatatcttt catatctttt acagtaacaa taccttttaa tgtttttgct
    22441 ctatctataa ttagtaagct atcaacctta ctcgttctca taatttctat tccttgagtt
    22501 acagttctag tagaattaac agcaatagga ttttttatca taatatctct tgcttttata
    22561 tattctggat tatcccaaac tctatcttct ccgataaaat cttttacaaa gtcatttgca
    22621 ggctttctaa gtatattttc gggagtatca tattgtgcta ttcttccatc cttcataata
    22681 caaattttat cagctatctt taaagcctca tccatatcat gagttacaaa tattatagtt
    22741 tttttcaatt catcttgaag agaaaataat tgttcttgta aagatgttct cgttattggg
    22801 tctaaagcac taaaaggctc atccatcaat attatttcag catcagtagc aatggctctt
    22861 gcaacaccga ttctttgttg ctgtccacca ctaagttctg aaggatactt attcaaaaat
    22921 tcatcactat caagtcctac catctcaagt agttgcaacg ttcttttttc aatttcttca
    22981 acggattttt ccttttttag gcgtggaatt agctctatat tttcttttat tgtaagatga
    23041 gggaataggc ctgtgttctg tataacatat cctatttttc ttctaagctc tatttcattt
    23101 tcctgagaaa ttggtttgcc attaatatat atctcaccag atgtaggttt tattaatttg
    23161 tttataagct tcaaagtagt agtctttcca caaccacttg aaccaatcaa aactaccaat
    23221 gtacctgttt ctacaactag agaaatatca tctaatataa cattatttcc tatttttttt
    23281 gttacatttc ttatctctat cataatttat catccccttt ttcgaacaag caaccttctt
    23341 caatattata agttgttttt ataattatat catactattt tatttatgta aacaaagtac
    23401 gatttttagg tcactatttg tctgaatatt gctacaaata taaagtattt atatatagta
    23461 tataatacat aatgtcaaaa aacaaaaaat ataaaaatat tcataaaata acactagcct
    23521 caattatata gtattaaagc tagtgttatt tcatttaaac aaaactcaca tttggatact
    23581 atccatgtat tcaaataatg taatatcttt ataagtttct tttttatcac ttaggtttga
    23641 tattgtaact cccaatagcc taatttgttt tccattaaca tcaacatttc tcaacaaatt
    23701 atctacacca cttcttatat cattatattc gtcaatatag tgttctaaac taaggcttct
    23761 agttatcttt gtaaagtcct catatttaat ttttaatgtt aatgtttttc caaacttctc
    23821 agagtttttt aatctatgac atacttcttc acaaagttca tcaagaatgt tgcgtgtttc
    23881 ttcttcatca atatccaaat tatgacttaa tgtagtctca gccccaacag attttctaac
    23941 cctatttggt tccactggtc tatcgtctat tcctctagca aatttatata attcataacc
    24001 tctttttttg aatatatttt caagttcaaa taaatttaaa caccttaaat catatccagt
    24061 ttttatacct aaatttttaa gagtatttga agtaactttt ccaacaccaa aaaatttatt
    24121 cacaggtaat ttatctaaaa agtcctgggc attttcttcg gttattacag ttaacccatt
    24181 tggctttctt aagtctgatg caatcttagc aagaaactta ttgtatgaca caccagctga
    24241 agaagtaaga ccaacttctc taaatatatc tttttttatt tgctttgcta tctcaattga
    24301 tgaatcaata ttttttttat tttttgttac atctaagtaa gcttcatcta aagataatgg
    24361 ttcaactaaa tccgtgtatc tataaaatat atctcttatt tgctctgaca cactcttata
    24421 aacatcaaat cgaggtctta caaaaactgc atatggacac ctattgtaag ctacagctga
    24481 tggcatagct gaatggatac caaattttct agcttcataa gaacacgttg caaccacacc
    24541 tcggctttgt ggatttccac cgacaataac aggtcttcct tttaattttt tattatctct
    24601 ttgttctata gatgcataaa aagcgtccat atctatatga attatttttc tataatgttt
    24661 cattattatc accttttaaa gtataaatag attaatttta tttatattac tttttaatta
    24721 taccaaactt atgtttcttt ttggtatttt ttcattattt tctttatata ttcatatttt
    24781 ccataaataa aaccatctat aatccattaa cttcaatata atttataaaa aatccttaaa
    24841 aacacttgca aaaactatat aaaagcttta caataggtat tccaaggaac taaatttaaa
    24901 attccttatg gataacagta tatatattta atttatggga tgttttaaaa acaaaagact
    24961 gtcttatgca agacagccta ctgattttat tataattgta atggactgct caaactatta
    25021 ctttaaaaca gcccatattt ttttatataa ttttaactat agtaaagatt ttgtgaagga
    25081 tattctgggt cacaagttac atctatacca agctttctaa atgtttgttc atcatctcta
    25141 tttaatatag tagtagaatg agcttgacac ccttttaata atgctaactt ttccatagca
    25201 aattgtgcag ttggattagt tacagcacaa atactaagtg cagttaacac ctcttggcaa
    25261 ctaagtgaaa catttctact agctaaagtc tttgttttta agtttatgat aggttctaat
    25321 attacaggtg atattaagtg catatcatca gatatattgg ctaaatgttt aatggcattt
    25381 aatactactg ctgcagttcc attcattaaa tcagaaccct taccagttaa tattgtacca
    25441 tcttctaatt ctaatgcaac tacaggacaa gtatcattct tgtcagcact ttctttcaat
    25501 ttattactgt agtttctagc aggtaataca acatttctat cttctggctt taagttaagc
    25561 tcttccataa tcattttcat tctatcataa gcacctttat caacttgtcc ctttttatac
    25621 tcacaggcag ttttaaagta tcttcttatt atttcttcta tagaagcttt tcttattact
    25681 tcatcatcta ttattccaaa gccaactcta ttaacaccca tatcagttgg agattggaaa
    25741 attgattctt ttccagttat cttttctatt atttttttaa gcactggaaa taattccaaa
    25801 tctctattgt agtttactga catttcacca tacgtttcaa ggtggaatga atctatcata
    25861 ttcacatctt ttaaatcaac tgtagctgct tcataagcta tattcaaagg atgttttaca
    25921 ggtacattcc aaactgggaa tgtctcaaac ttagaatatc caactacatt acctctttta
    25981 ttttcatgat acaactgact tagacaagta ccaagttttc cactattagg tcctggtgct
    26041 gtgactacta ctattggctt tgtagtttct atatattcat ttgctccata tccctcatca
    26101 ctaactatag tctcaacatc tgacggatat ccctttgttg gataatgctt ataaacttta
    26161 attcctctac gttctaattt atttataaat acagttgtag caggttgtcc ttcaaatcta
    26221 gtaattacta cactatttac atctagttca taacctctta aatcatctat taatcttaaa
    26281 acttccatat cataagtgat accaaagtct cctcttattt tgtttctttc tatatctcct
    26341 gcatagacac aaattacaac ttcaactttt tctttcatat gttgtaatac ttttatcttt
    26401 gcattttcat caaatcctgg aagtactctt tttgcatgaa ggtctcccat caattttcct
    26461 ccaaactcta aataaagttt gtcaaaatta tttactcttt ctaagatata tttagactgc
    26521 tcttctaaat attttttgtg gtcaaatcct actttcatct taacacctca ctaaattaaa
    26581 tttcttattg ataacagtat atttatatat atttttttag taaaacatct tataaaaaaa
    26641 tgttaatact ttttcactca aagtaatatt atacaattaa gattaatttt tttcaagata
    26701 gttttatggt aaataagata tacctaatat aactaataaa ataagaatac tatattttta
    26761 tatataagta taatattctc accttagcat taatttattt caatattttc atatatcttt
    26821 tattctaaat tcaatacttt tctaatatct tctatacctt gataaacttc ttgtttagaa
    26881 aaattcatag cttctaattc ttcatcagtt ttttccataa gcatagtata aaattctatt
    26941 gctatatact gcatattttc actatttaca ctcttagctt tatcaaataa aatttcttct
    27001 gcttcgttta catttccctg aaaaactaat ctttttaaag ttataagtat aacttcttct
    27061 tctgtattat acactaaatc tttttcttca tattcactgt atttttttcc caataaaagt
    27121 cttgcaacca taagttttat ctcattgaaa atcttatcca ctatagccat ttttacatct
    27181 cctataaata aattttattt tctttttaat tatatcagac tttatcgtaa aaattattat
    27241 atgtaaatga aataattcaa aaataaattt taacaataaa aaaaagaagg tagcggggga
    27301 tttccgacta ccttcaaaca ctagattgtg attggtttgg tattttattt atacccacca
    27361 taagctttat taaatcatct aaattgattt ttttagcatc cacatcctcc atcaaaaacg
    27421 tcaccacatt cacaaagtat taataataat attaagaaag gtatccatgc acataagtcc
    27481 atttcagccc aacaatcttg gaatgctaag aataagaaga ataatattat tatccaccaa
    27541 gcacatccac caaatccgcc ttcaccaaaa aatctatcca acataatatg ttacctccta
    27601 gtcattttgt atgtggagtt tcagctccta aaatatacta tgtttaaggg gtaatatttg
    27661 ctaatgattt ttttaaattt ttttagatat ttttaaaaaa attattgatt cacactcaat
    27721 gtcttaccat cactattgat aactacctct ccattagaag tcaaaaatgt ttttatattc
    27781 aatctttcca atatttttaa aacaccttcc tctggttctt ttttctctga acatgtaata
    27841 acagcatatt ggggtgaaat agactctaaa aatgtttcag ttaatttgtc atatcttcca
    27901 tgatgaggca ttttaacaaa atcatatttt aaagtatttc catttataaa ctctgacaat
    27961 ctttcttcct ctgcatctcc tgcaaataaa aacttatgtg ctccatagct tatattagtg
    28021 attattgaat aatcatttga actctcgtac ttgctttttg aagccggatg tatgtttatt
    28081 tctgcactat tgattacaat attcatatta tcttttagta gcactggttc tatatcagct
    28141 tttttaagtg aatcaatata ttcatcatat tgcttactat ctttcttata atttgcttgt
    28201 ataatattct ttactttaac actagataac acactatcta ctccacctat atggtcctta
    28261 tctaaatgag ttaaaattaa atagtcaagt gtatttattc ctttttcttt taacctatcc
    28321 actatttgtt ttccattttt atcttctcct gtatcaatca ttatgacttt gttacctatt
    28381 tcaaccaata tacagtcaga ctttccagta cttaatatag tagtcttaaa tgcagtattt
    28441 tttgtgctac tctgaatatt attttgactc acatcatttt tgtcactttt taaataagat
    28501 tcattcgttg attttatctt actattagta gttatatttg ttacaagcaa taatattact
    28561 attatagata atgtagtaac taaaaacagg atatctttta atactatttt cctcatccaa
    28621 aagctcctat aaattttatt tattacatat ttatagtata gcaaccttaa ctctgtaaaa
    28681 tacacatata aaaagggcaa attttaggca tatttgtggc atgataaaaa aatgactgta
    28741 ccaaaacaat tatctttcta aatttacatc ttcaaattct ttaatcttat cattagataa
    28801 aacactcttt ttagtagatt gtccattttt tctatcaaaa gtatttttag cttttacacc
    28861 tgataaaaac ttacctgctc cattaataca accttcttca cacatcattc cttctataaa
    28921 attaccttct aatcttccca atttagccat tgtcattgtc tttttaattt gtcttggacc
    28981 agatactttt ataggttcaa aatcaaaact aagccccttt tcagcaatat agttctgtac
    29041 tgatttggca agtccaccag atgctccaaa tccccttcca aaaatcgaac catcatttat
    29101 atcttcattt gaacattttg ataaatctat attaaatgct tcaaataatg ccattagttc
    29161 ttcaaaagta agtacataat ctactgaatc ttttaaactt ttctctgttg cctcactctt
    29221 tttagctgta catggaccta taaatacaac tttagcatca gaatctattt tttttactaa
    29281 tcttcctgtt gctaccatag gagacactgt agatgatatt ctatcttttt catctgggaa
    29341 catcttctct atatacttaa aaaatcccgg acaacatgaa tttgtcatgt aattatctcc
    29401 tgattttatt ctttcaataa gttcattgct ttcatgaact gtaactgcat ctgctccaca
    29461 agaagcttct atcatatcta caaatcccag tgattttata gcatttttta actgaccata
    29521 tgtaatatta ctatctattt gacctgttat agctggagct actattgcat acatattttc
    29581 tttctttgca agtttttttg caacaggtgc tatcaaactc ttatcagata ttgctccaaa
    29641 tggacatgct gacatacatg ctccacaatt tatacaatta tcttcatgta tcattgcttt
    29701 catagtgttt ctattaaaat ccaaagctcc tgttggacaa acgcttttac aaggtcttac
    29761 aacttctgat atagcatcat attgacatga acttttgcac attccacaag ccttacataa
    29821 atcatgattt atatatgctc tcccatttat ataagaaatt gccccaaatt tacatgcttc
    29881 cttacatcta tgagccaaac accctctaca aagctctgta actgtaaatt catttattgg
    29941 acatctatca catgctgctt caactatata tataatttgc tcatctgtgt ccaaactaac
    30001 tgaatctgga tttatatctc catatttact atttggagtt aaacttaatg caagttgcgc
    30061 cctttcaaga actacttctc tctctttata aacacaacat ctatatctcg ccttttctcc
    30121 tttaattatt tcatatggaa ttttttctat attttctttt gttaaatttt cttcaataga
    30181 tagtcttgct actgctgtta aaacttcatg ttttaacctt tttagttgcg tttcaaattc
    30241 aaacataagt aatcctccct ataaatcaca cctttttgct atatttctac tattatgtat
    30301 attgtatttt ttatttattt ctataaatta ttataacata ggcatatact ttgttaagtt
    30361 atatacaaaa tattatatat gtaattttta ttttaagtgt atataatttt tattttagtt
    30421 gttcaataat taaatatata aataaaaata gagttgtcca aaagttaaac ctcaacttag
    30481 aacaactcta ttaacaatat gtatttttgt tgctttgtat tatctttatt tttctaaatt
    30541 tatattacta aaatctttta tctttgtatt tgctaagaca cttttcttag ttgattgaga
    30601 attttttcta tcaaaagtgg ctttaacctt tgcacctgat aagaatttac cagaaccatt
    30661 tatacaacca ccttcacaca tcattccttc tataaaatta ccttctagct ttcctaaatt
    30721 agccatagtc atagttttct tgatttctct tgaaccagaa atctttacag gttcaaaatt
    30781 aacaccaata cctttttcag caagataatt ttctatagct tttgtaagac caccagcagc
    30841 tccaaaacct cttccaaaaa ttgatgcatc atctatatct tcatttgaac acttagccaa
    30901 gtctatatca aatgcctcaa ataatgccat tatttcttca aaagtaagta cataatcaac
    30961 agctcctttt aattctttct tagctgcctc actctttttg gctgtacatg gtcctatgaa
    31021 tacaacttta gcatctggtt catgactttt tataaatcta ccactagcta tcataggaga
    31081 cactgtagaa gatatttttc ctacatgatt tgggtatgtt ttttctatat aaccaacaaa
    31141 tcctggacaa caagaatttg tcataaaagc ttctcccttt tccattcttt cagcaaattc
    31201 taagctttca tgaactgtaa ctgcatctgc tccacaagct gcttctaata catcaacaaa
    31261 tcctagtgat tttatagcat tttttatttg accatatgta acatttgctt caacttgacc
    31321 tgttatagct ggagctacca ccgcatacat tttctctttt tgaactaact ttctagctac
    31381 aggagctatc aaactcttat cagatattgc tccaaatgga catgctgaca tacatgctcc
    31441 acagtttaaa catttatcct catgtatcat agctttcata ttttctctat caaatcctaa
    31501 ggcattagtt ggacaaacac tcttacatgg tctaacaacc tctgagatgg catcatattg
    31561 acaagctttt ttacacattc cacaagcctt acataattca tgatttatat aggccattcc
    31621 tccgacatgt gttatagctc caaatttaca agcttcttta catctatgtg ctagacatcc
    31681 tctacaaata tctgttactg taaattcatt tattggacaa ctgtcacatg cagcttccaa
    31741 aatatatata atttgttcat cttcttctat atccattgta tctaaatcta tcttatcttg
    31801 acctggttgt aaccccatac ttacatttac tctctcagat attatagctc tttctttata
    31861 aacacagcat ctgtatgtag gtttctcacc ttttattatt tcatactgaa tattatccat
    31921 tgcttctctg gtaaggttat cttcttttcc aagtctagct attgcagtta aaacatcatg
    31981 tcttaatttg tgtatttgtg tttcaaattg aaacatttta ataccacccc cgtaaatgat
    32041 tttatacgat accattataa cacaatatgt ccttttatta atatatacat aaaatattat
    32101 atgtttaaat tttattttat cgaatatata tagtgttttt ttgttttatt atataatatt
    32161 attgatattt ctgaaatttc actattttta tttttacttt tcaatctaat atataatatt
    32221 ttttattata tattttaatt ttacttttta cttacatacc tttttgttac attttttgat
    32281 attaaattta ttatctacat ttacattttc gtcaaatttt acaatacttc tcactgtata
    32341 atttaacaat ttttattaaa ttctaaaagt aattaatttt tttaaaaatt ttatttgctt
    32401 ttatttaaaa tttatgttat attaatagaa cagacttatt tttttagttt gtatttttta
    32461 ataatgcgga ggttttctta taatgaaaaa cggaatagta aaatggttta acaatgaaaa
    32521 aggatttgga ttcatatctg tagagggaga agatgatgtt ttcgtacatt tctcagctat
    32581 acaaaatgat ggatacaaaa ctttagaaga aggcgaaaag gttagctttg atataactca
    32641 aggtaataga ggacctcaag ctgaaaacgt aaatagaata taattattta atttaaatat
    32701 atatatttta gaaaaggagc tatcgagggc tcttttttgt tgtttattat atttattttt
    32761 aattacaaaa ataagaagtt actttagaaa agcgtcaaac ttaaaataac ttcttatatt
    32821 ataatatata ctatttatat aaaatactct atttaatttt atcagatatt attaagcata
    32881 actctcttaa gattttacaa gctataactg tcgatacacc tgttgtatcg taatcagggc
    32941 ttaactctac aatgtcacaa ccaactatat ttatattaga gttttttata atcttaaaaa
    33001 tctcttgaaa ctctctataa tttacaccac caggttctgg tgtacctgtt cctggaaaca
    33061 cagatgcatc caatacatct aaatctatag ttagataaat attctttcca tttagcatat
    33121 taactatatt ttcaaacgta tctattcctc ctatttccat gtatgtgtgt ttttcttctg
    33181 tagcaaattt aaattcttct tttgtcccag accttatacc aaattgaaat attttattat
    33241 cacctacaat atcccatatt cttttaatta ctgttgcatg agaattttta ctattattat
    33301 attcttccct caaatcagta tgggcatcaa aatgaattac atatatatca ttatactttt
    33361 catgtactgc tttaaaggct ggtaatgtaa ctaaatgctc tcctccaatc ataaagggta
    33421 cctttgaatc tctaacaatc ttatatgtct cttgatagat ttcttttaag acttgttctg
    33481 tacttccaac actaatttct aaatctccat aatcacatat attataatcc tctaaatcca
    33541 aatctaaaaa aggactatat gtctcaagac cgtaaaattc ttttctcata gagctacttg
    33601 caaatctagc cccaggtctg ttagaagtag ttccatcaaa tccaacacca aatactataa
    33661 gattagattc ttcataattt ttgttcatac tcataaaagt gttcatatga tagaaattat
    33721 tcttcatcca gcatctcctt cacgtattga ggtaacataa acgaacctaa atgtatatca
    33781 ctattataat atttagtttt taaacttaat ttctcccatc catttctatc ttgatttttt
    33841 actggattaa gtttttttga agcaaatcca aacaaccagt gaccagatgg atatgttggt
    33901 atatgtgctt gataaacttc tgatattgga aatatctgtt ttaacttttt attagctctt
    33961 ttcatctctt tagcattaaa gtcaaaatac ggactttcac tttgatttac taaaattcca
    34021 tcatcagtca gtattctata acaatcctta taaaaatcag ttgagaaaag cccttcacct
    34081 ggtcctattg ggtcagttga atctactatt atcaggtcat atgatttatc atgtgcacac
    34141 ttaacaaaat taacaccatc ttcaaaatat aaactcactc ttttatcatc taatttacat
    34201 gagcatatat ccatatactc tttagataca tctacaacca ttttatctat ttcaaccatg
    34261 tcaatctttt ctatttgagg ataacggctt aattctctta ctgtacctcc atcacctcca
    34321 cctatgacta atactttctt tatgtttaaa tttgtagcca taggaacatg agttatcatc
    34381 tcatggtata taaattcatc tttatatgtt accatcatta atccatctat tgttagaaat
    34441 tttccaaatt catcactatc aaacacatct atcctttgaa attgagactt tccttcaaat
    34501 agatgtttat ttacttttat agaaaatctt acattttctg tccattcttc tgtataccaa
    34561 agttccatat aataatcctc actttctctt gtatgtttta tactgcttct ggtttatgag
    34621 taatcttacc taaatctttt tttgaatatt ttttaatttt tgtagttaag cctcttggaa
    34681 tttctgtaga ctcgcttctt tcagacttta aaagttgctc taataattca aaacttttcc
    34741 atgggtctat atcaccacaa gtaaaaaaat ctgctgctgc ataaccatat tcaggccatg
    34801 tatgtattgt caaatgagat tcagcaatta taacagctcc tgaaaccccc caaggattaa
    34861 aatggtggaa tacagaatcc acaattgtcg cttttgcatt taatgctgaa tcattcataa
    34921 aattttctat aagacgtggg tctttaagta cgttttcatc acaattatag tattctacta
    34981 gtatatgtct tcctagtgtt tcaaatttca tttcaacccc aactccttta tacttttaat
    35041 aagttctatt tgataaactc tacttaacaa acacttgccc ttgcaaaata aagtaattta
    35101 ttttattact agtattctat ctaagttttt atcttgtaca tctgtaagat atgcattgct
    35161 attttttaag aaaataatat actccataat ttcttctgtt atcaattctc ctggagcaat
    35221 aatcggtata cctggtggat atgccattat tgattctcca caaattctat ctatacatga
    35281 attgatttct acactttcct ttggtgcata aaaagcttct cttggattaa gtttaataat
    35341 tggatttatt tgaaccatat taaattcatt taatgttgat tcttttctat aaatctttgc
    35401 aattatagaa agtgccttta ctaatctatc tatatctgat ttatttgttc caatggacac
    35461 aagtgccagt atattatatg aatctcccaa ttctacttga attgaaaaat ttttatataa
    35521 taaatcgtat acttcaaatc cagtcaaatt taattctttt acatttatac acaattttgt
    35581 ttcatctata aatttaacac ctttttgttt caatatttct gtagataaaa cttttattcc
    35641 atcaattttg ttcaatttag attttgcata cctagataga tttaatgctt ttgacaattg
    35701 cttttcacca ttctcaacta gattaactct agcaccatct atacttgcca taagcaaata
    35761 agatgctgat gttgattgta gcatattgat tgattgaaga accttttcaa aacttacatt
    35821 atctctattc aataagagtg ctgaagattg tgtcaatgct cctccagttt tatgtatact
    35881 tacagctacc atgtcagctc ccaaacttat tgcagaagga ggtaaatcta aatgaaatgg
    35941 aaaatgtgca ccatgagctt catcaactaa cactaaaaca ttatttttat ggcatagttc
    36001 tataatactc tcaaggtctg cacaaactcc atagtaagtt ggattaagga aaaataatgc
    36061 ttttatatta caatcttttt ctatctctgt tctaactttt tcaagagtaa tatttaaact
    36121 tatacctagt ttttcatcaa attctggttg tataaatatt ggtattcctc cacaaagtat
    36181 taacgcattt attactgatt tatgtatgtt tcttggaagt aatacttttt cacctggttt
    36241 tataacactc aaaatcattg catgtattgc ttgagttgtg ccattcgtta taaagaatgc
    36301 ctcatcagcc atatatgctt gtgctaacaa atcttgtgca ttttttataa tcccatttgg
    36361 cgcagataca ttatccatag ttggtgatga atttatatcc attttcatga gactttcacc
    36421 tagatattta tttaatatag ctacacctct attttttaca tgtccaggca catcaaaaca
    36481 agctatatct ttctctgagt attcctttaa cgactctaat aatggagcac actcatagct
    36541 taattcaact gcatttgcaa actcgctatc catgatttca aattcatctc ctctctatat
    36601 tcaaatattt ttaatattta ttatttatta tttctatttt ttatttttac ttttattaaa
    36661 ctcatgatat ttattatatt aacatcccag catttttaca agtgtttttt tgaagttact
    36721 caaaaacata tacattagct atatcaatat ttataaactt tttaattttt tgttgtttat
    36781 attaattttt ttaaaactta gtatttataa actttcttat tttttattat tttggttttt
    36841 ttactttttt gagttttagt aagcttttga gtttactatt tttaatttat aagtatttta
    36901 ttactaaact tttatattat tctt
//
LOCUS       DAGQVA010000038        36742 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.038, whole genome shotgun sequence.
ACCESSION   DAGQVA010000038 DAGQVA010000000
VERSION     DAGQVA010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.038"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..307
                     /locus_tag="MIV85_002042"
     CDS             <1..307
                     /locus_tag="MIV85_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961377.1"
                     /translation="CPVEALSNILGKKWVAIIIWKIQEDKKRFGELQRAIPDCSKKML
                     VQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWSNKNLNCDKY"
     gene            444..1721
                     /locus_tag="MIV85_002043"
     CDS             444..1721
                     /locus_tag="MIV85_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBY2961378.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKEQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1842..3230
                     /locus_tag="MIV85_002044"
     CDS             1842..3230
                     /locus_tag="MIV85_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBY2961379.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3601..4314
                     /locus_tag="MIV85_002045"
     CDS             3601..4314
                     /locus_tag="MIV85_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBY2961380.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVGLSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4432..5301
                     /locus_tag="MIV85_002046"
     CDS             4432..5301
                     /locus_tag="MIV85_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBY2961381.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANINLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKELVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5456..6601)
                     /locus_tag="MIV85_002047"
     CDS             complement(5456..6601)
                     /locus_tag="MIV85_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBY2961382.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(6934..7710)
                     /locus_tag="MIV85_002048"
     CDS             complement(6934..7710)
                     /locus_tag="MIV85_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBY2961383.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8292..9266
                     /locus_tag="MIV85_002049"
     CDS             8292..9266
                     /locus_tag="MIV85_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBY2961384.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9364..9669
                     /locus_tag="MIV85_002050"
     CDS             9364..9669
                     /locus_tag="MIV85_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBY2961385.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9825..10985
                     /locus_tag="MIV85_002051"
     CDS             9825..10985
                     /locus_tag="MIV85_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBY2961386.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            11035..11937
                     /locus_tag="MIV85_002052"
     CDS             11035..11937
                     /locus_tag="MIV85_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBY2961387.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            12017..12910
                     /locus_tag="MIV85_002053"
     CDS             12017..12910
                     /locus_tag="MIV85_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBY2961388.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      12963..13144
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13372..14502
                     /locus_tag="MIV85_002054"
     CDS             13372..14502
                     /locus_tag="MIV85_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2961389.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14574..15599
                     /locus_tag="MIV85_002055"
     CDS             14574..15599
                     /locus_tag="MIV85_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBY2961390.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            15602..16798
                     /locus_tag="MIV85_002056"
     CDS             15602..16798
                     /locus_tag="MIV85_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961391.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(16926..17651)
                     /locus_tag="MIV85_002057"
     CDS             complement(16926..17651)
                     /locus_tag="MIV85_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBY2961392.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            18129..20228
                     /gene="nrdE"
                     /locus_tag="MIV85_002058"
     CDS             18129..20228
                     /gene="nrdE"
                     /locus_tag="MIV85_002058"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBY2961393.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            20240..21211
                     /gene="nrdF"
                     /locus_tag="MIV85_002059"
     CDS             20240..21211
                     /gene="nrdF"
                     /locus_tag="MIV85_002059"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBY2961394.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            21287..21913
                     /locus_tag="MIV85_002060"
     CDS             21287..21913
                     /locus_tag="MIV85_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBY2961395.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            22308..22937
                     /locus_tag="MIV85_002061"
     CDS             22308..22937
                     /locus_tag="MIV85_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961396.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIITECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            22938..23720
                     /locus_tag="MIV85_002062"
     CDS             22938..23720
                     /locus_tag="MIV85_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961397.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            23713..24591
                     /locus_tag="MIV85_002063"
     CDS             23713..24591
                     /locus_tag="MIV85_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961398.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNKEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIRSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            24624..25583
                     /locus_tag="MIV85_002064"
     CDS             24624..25583
                     /locus_tag="MIV85_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2961399.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            25897..26589
                     /locus_tag="MIV85_002065"
     CDS             25897..26589
                     /locus_tag="MIV85_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961400.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            26599..27603
                     /locus_tag="MIV85_002066"
     CDS             26599..27603
                     /locus_tag="MIV85_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2961401.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFAP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKGVNSLIKM
                     "
     gene            27851..28702
                     /locus_tag="MIV85_002067"
     CDS             27851..28702
                     /locus_tag="MIV85_002067"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBY2961402.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            28806..29552
                     /locus_tag="MIV85_002068"
     CDS             28806..29552
                     /locus_tag="MIV85_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961403.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            29552..31468
                     /locus_tag="MIV85_002069"
     CDS             29552..31468
                     /locus_tag="MIV85_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961404.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNKNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            31747..32664
                     /locus_tag="MIV85_002070"
     CDS             31747..32664
                     /locus_tag="MIV85_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBY2961405.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILLEIEKMKKIY"
     gene            32742..33479
                     /gene="cas6"
                     /locus_tag="MIV85_002071"
     CDS             32742..33479
                     /gene="cas6"
                     /locus_tag="MIV85_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBY2961406.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            33485..35335
                     /gene="cas8a1"
                     /locus_tag="MIV85_002072"
     CDS             33485..35335
                     /gene="cas8a1"
                     /locus_tag="MIV85_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBY2961407.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNMIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSN
                     VLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVY
                     KMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFS
                     PSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLPNEKEEK"
     gene            35337..36251
                     /gene="cas7i"
                     /locus_tag="MIV85_002073"
     CDS             35337..36251
                     /gene="cas7i"
                     /locus_tag="MIV85_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBY2961408.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            36253..>36742
                     /gene="cas5b"
                     /locus_tag="MIV85_002074"
     CDS             36253..>36742
                     /gene="cas5b"
                     /locus_tag="MIV85_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBY2961409.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMP"
BASE COUNT        14466 a         3702 c         6459 g        12115 t
ORIGIN      
        1 ttgtccagta gaagctttat caaatatttt aggtaaaaaa tgggtggcta taattatatg
       61 gaaaatacaa gaagataaaa aacgatttgg agagctacaa agagctatac cagactgtag
      121 taagaaaatg ttagttcaac aactagattt tttaattgaa caggggatta tagtcaacca
      181 aaaaaagttg gttaataatg ttgtagagtc aacatatttt ttaagtgaat caggattacg
      241 attgcttcct gtcatggaaa aaatgattat gtggagcaat aaaaatttaa attgtgataa
      301 atactaaaat ttactctgta agtaatgaaa atttaattaa gctatgagta gaaaaatgta
      361 ttaaaattac ataatttttt agttagattt taatttagaa atgggattgt aatattggaa
      421 ataaaataag gaggaatttt aatttgcaaa atgtaaattt atttttagta tttatagaag
      481 gtatagtatc attcttttca ccatgtatac tgccaatttt gcctatttat ttgagtatat
      541 tgtcaaatag tagtgtagaa aatttaaaag aaggaaagac gagttttata ggaagttctt
      601 tatttaaaaa tactatattt tttgctcttg gaatctcaac aacattcttt atattgggtt
      661 catcagtaaa agtattgagt atgtttttta atgaaaataa agatttaata atgtttattg
      721 gtgggattat aattattatc atgggattat tttacatggg aataattaaa tcttcaatat
      781 tgaatagaga aaaaagattt aatgttaagt ttaaagaaat gaaagcaata acagctttta
      841 tattaggttt tacgtttagt tttggatgga caccttgtat tggtccaata ttggcatctg
      901 tattagtcat ggtttcaagt tcaagtaatc atcttagtgc caatctttta atagcagtat
      961 atactattgg ttttattttg ccattcataa ttacagctat gttttacagt aaactattta
     1021 aaactataga taagataaaa tctaacatgg aaattattaa aaaaataggt gggattatac
     1081 ttatagtatc aggaatatta atgatggtaa atggatttgg aagtataagc aaacacttta
     1141 atacgtcaca aaatagtaaa attgaaagca agcaagaaga aaataagcga gaaaattcta
     1201 ctgataaaga agaaaattct gatggtaatg atagtcaaaa agactctaat aatgacaata
     1261 atgataaagg gtctaatgat gaagatagaa taaagtctat tgattttact ttaacagacc
     1321 agtatggtaa aacacataaa ttaagtgatt atgaaggcaa agttgtattc ttaaatttct
     1381 gggctacatg gtgtcctcca tgtaaagaag aaatgcctta tatagaacaa ctgtataaag
     1441 actataataa aaataatgat gatgtagtaa ttttaggagt agcttcacct aatttaggta
     1501 gagaaggttc aagggaacat gtagttaact tcttaaaaga acaaggttat acattccctg
     1561 ttgtacttga tgaagatgga gcattagcat atcaatatgg aattaatgct tttccaacta
     1621 catttataat tgacaaggaa ggatatgtaa ctcagtatat tccaggagct atggataagg
     1681 caactatggc atcatttatt gaaaatcaga gaaataaata aaagtattta agtataagtt
     1741 tataaatcaa tttaaggtta caaaaaagtg cctaattgta ccacctaaat aatcttgtta
     1801 tagtaaaagt ataaacaata caagaaaggg ttgaatttta tatgaaaaaa acatttgatg
     1861 ctataataat aggatttgga aaaggtggaa aaacattagc aggggatttg gcaaacaggg
     1921 gattaaaagt agctttaata gaaaagtcaa acaagatgta tggtggaaca tgtgtaaatg
     1981 tggcatgtat accaacaaaa agcttagaaa attcagcaaa cagcgtaaaa acaaagaata
     2041 taaattcttg ggatgaagta caagctgaat atgagaaagc tatagataaa aaagaaactt
     2101 taattacaaa actcagagaa gctaactata ataaattaaa ttcaaatgag aatgtaacta
     2161 tattcacagg aatgggaact ttcattgatg aaaaaacagt tcaagtcaaa actgaaaatg
     2221 aaatttatga gttagtagca gataatatat ttattaatac tggttcaaga ccatttatac
     2281 ctaatattaa gggaattgaa aataagaata tagtatatga tagtgagtct cttatgaatc
     2341 taagagtttt acctaaaaaa atgacaatta taggagctgg atttataggt ttagaatttg
     2401 ctggtattta tagttcattt ggagcagaag ttacaatatt aaactctaat aatggcattt
     2461 taccaaatga agatgttgag gattcagaag aaataataaa attacttgca aagagaaatg
     2521 taaaaattgt taataatgca aatataaaag agattaaaga agtttctgaa ttagcaatag
     2581 tagaatatga agtagatggt aaatctaaag aattaacaag taatatgata cttgtagcta
     2641 caggaagaaa agcaaacact gaagggctag ggctagaaaa tgcaggtata gaattaaatg
     2701 aaagaggatt tattaaagtc tcagaaactc ttaagactaa taaagagcat atatgggcta
     2761 taggagatat aaatggaggt ccacaattta cttatatttc attggatgat tatcgcatag
     2821 ttattaatca gttatttgga gataagacta gaacaactaa tgatagaaag aatatcccaa
     2881 attctatatt tataagtcca gcattttcaa gagttggtct taatgttaag caagctaaag
     2941 aaaagggata tgaagtatta gtggcaaaga tgccagtaga agcaattcca agagctaaac
     3001 agattggcaa ggcagatggg tttataaaaa tagtgataga taaaaaatcc aataagatac
     3061 ttggagctag tatgatatgt gaaaattcaa gtgagattat ccatcttatt caattagctg
     3121 tagatttaga agtagagtat acatatttaa gagaccgtgt ttatgcacat ccaactatga
     3181 cagaagctct taatgatatt ctatctccta atatgataaa agaagtataa cataagttta
     3241 atatataaat ctaaaattat cattataagt agattttaga aagaggctat ctcaaaaaat
     3301 agagataagt ctctttttta ctgtttaaat aataaaaata tatttgattt tataaaagaa
     3361 gattatttta tgagctaaaa agtttattta gaaacactac ctatttatgt tataaagtta
     3421 taaatataat atagaatcta ttattctgta ttattaagtg gggttaagcg ttataattaa
     3481 ttataaatat tgaataatct aaatggataa gataatggta ttaaaaatta tcttaaaagg
     3541 tgaaataatc tgtatttaat gtagtacagt tatatcttta aagcaaggtg gtgaaatgat
     3601 ataaataaga tatctaaaag agggtttgat gatagtgata aaagatggtt ttcaagtaaa
     3661 gaattaacaa gacttataaa ggctaaagaa gaaatagaat ggttattaaa tagggattac
     3721 aaaatagacc cagtcgttac ttttgttggt gatagatatc agttttctat aagacaaaga
     3781 gatgcattaa aaagggcagt ctgtactgat gaaaaaaata ttataagaca atcaaagagg
     3841 ctttctctag ataaaatcaa agaagatacc gtaaatatag atggctttaa tttgataata
     3901 tccatagagg taggattatc tggtggtact ctagtaatag gaagtgatgg caatataaga
     3961 gatttagcag gtcttagggg aacctataag attatagata aaacagaaga agctttgaat
     4021 ctgataggta aattttttaa taaatacaat gcacagaatc ttaaatttta tttagatgct
     4081 ccagtttcta attcaggaaa tttaaagtat aggatattag agcatgccaa aacttgggga
     4141 attgaaactg aagtagaatt agtaaaaaat gcagatgttg tattggaaaa attagataga
     4201 gtagttagta gtgatgcagt catagttgac aagtgtataa gttattttaa tgtggctaga
     4261 ggtataattg aagagtatat taaagaatgt aatatcataa atttaaataa atagataaat
     4321 ataggtgaga atatataagt atatgtagca atattcttag taatacaagt aaagtttgaa
     4381 aataggagaa cgaatacata tcgaatttca taaaatgttg taaaaagaca tatgagagga
     4441 tggatatgtg tgaaattaac taaactaaat attaaaaaat atagagcacc tatatataaa
     4501 tatgctttag caaatataaa tttgaggtct gctaaatcta ccaattcaag tatcataaca
     4561 gtaatacctc agggagccaa aatggaagta ttggatgagg aagatgactg gattaaggtg
     4621 atgtacaatt ctcaagaagg atatgtgtat aaggagttgg tatcagtaag cgaatatgct
     4681 tggagtaact taaacttaag agaagataaa tctacaactt ccaatataat tacagtaatt
     4741 cctgaaaaat ctagggttga agtccttcaa gtagatggag attggagtaa ggttgtatat
     4801 gatgataaaa taggatatgt ttttaattat tttttatcaa ttgatgggaa taaaccaaat
     4861 gaattagatt ataagtattt ttatactgac atgattaaat ttgttaacga aaataatatt
     4921 aaaagtacta gcgattatct aattgtaaca gaccttagaa ataaatatac ttatattttt
     4981 aagaaagata atggaggatg gggacaactt tacaagtggc aatgtactat aggcaagcct
     5041 gagactccaa ctataacagg tatattttat ataagtggaa gaaaaccttc ttttggaacg
     5101 gatgagtatt cagttaagta tgctactaga attaaaggtg gatattacta tcattctgta
     5161 ctatatgatt caacaggaag ttatataata gatggcagac ttggtgaagc tcttagtcat
     5221 ggatgtataa gattaagtac ggaaaatgca aagtggatat atgataatat accagataca
     5281 acaacagtta taattcatta agaaaaattt tgagtttttt attgggataa tgattcttaa
     5341 attaatagga ttatatatta acttctcata aagagtacta tttaaaaagt gtaataagag
     5401 agtgctatta acaaaacaaa gatattttga ggcactctct tataaatata cataattaag
     5461 atattttcat aaacaattct ataatcttat ctttatcaaa gaaaacagga ttagcaccag
     5521 cacaagcatc tttcatagag ttttctgcaa gcaattcaaa attaggatta tcaacaccta
     5581 catcttttaa agattttggg attccaacct cttcagaaag agcttttatc ttatctatta
     5641 caaagtcaac acactcttta tctgatttat tatttacatc cattccaata acttcagcta
     5701 ttggtcggaa tttggcaggg gctgatttag cattttcctc ctcaactatt ggaagtagca
     5761 tggcattaca tactccatga ggtaaatcat ataaacctcc taattgatga gccatagcat
     5821 gtacatttcc aagacctgca ttactaaagg caattccatt taaaaaacaa gcataacaca
     5881 tttgttctct agcttctatg tcattaccat ttttaacagc tcttggaagg tatttaaata
     5941 tctgctttat agcatataag gcagttgaat ctgtaacatc ataagcacca ttagctacta
     6001 cagcttctat agcatgagtt agtgcatcca taccagttgc tgctgttaaa ttagatggtt
     6061 tgctaatcat taattctggg tcatttactg tcattgtggc tagtgaattg gtatcaacca
     6121 ttatcatctt tacatgtctg tcttcatcag ttataacata gtttattgta acttcagcag
     6181 atgtaccagc agtagtagtt atagctatga taggaagaca ttttttagaa gttttgttga
     6241 taccttcata gtctctaata tctcctccat tagtggctaa tatagagata gctttaccac
     6301 agtcttgtgg agaaccacct cctatagtta taacgaagtc gcaattttct gattttaata
     6361 ttttaagtcc tttattcaca ttagttacag ttggattttg tttaacttca tcataaacaa
     6421 caaagtctat atctatctga gataaaatat ctgttacttt ttttacagta ccatttgaaa
     6481 ctagaaattt atcactaaca ataaatgctt ttttagttcc taatgattta attgaatctt
     6541 tagcttcatt aagacatcct ttcccaagta aatttattgg tggtacataa taaatgctca
     6601 taactaaaat ctccttttat tttcattgat ttttatgtaa aaatatatat ctaacaattt
     6661 tcactaattt actcataata tatcgtatct tagattgaga tagggttgct ggttcttata
     6721 taagaactta attcgtaatt acgattatga ttagaattta acatagtatt tttatcatgt
     6781 caataaaaat ataaaaaata ttataaaaaa aacaaagtta ctgtagttaa atcagcaact
     6841 ttgtttttat agtataaatc aaataaatac attagtttaa aacaaaattt ttaattatta
     6901 tgttttgata tcttccatat acagaatatt aatctaattt attacaatgt cttcattacg
     6961 ttcttccatc attgattgaa tatttttctg agcatttaag agtaattttt ttatcagttc
     7021 tattttttcg tcattagctc taaataaagg cagtgttaca ctaacagcag ctcttataca
     7081 tccatttttt cttattggta cggcaagaca ttttaggtgt tccattgatt cctcacactc
     7141 tgaagctatt tgtgttcttt gaacttcaag aagctggtcg tataaaacat caaaatctgt
     7201 aattgatttt tctgtaaaac cttttagacc atctggatat aagcttatta gtttttcctt
     7261 gtcaaaatca cataaaagag cttttccaag acctgtacaa ttagcaggta ttttttttcc
     7321 aacataagaa ataagtctaa tcggttctgg agaatctact tttccaatat aaagaacttc
     7381 attattgtca agtataccaa gctgacaagt ttcagaacag gaattaacta tattagtcat
     7441 ttcgtcaatt atatagttaa aaatagttct tttttcaaaa aatgaagacc ctaatgtgta
     7501 agaacgtatc cctatagaat atttggatgt gtttttatca atagtaatgt attttctagc
     7561 attaagtgta tgaactatag gaaagatgct actttttgga gcattgataa catctgctat
     7621 ttctgtaaga gtatatccat tttcggattc tgctaatgct tctaaaatat ctaatatcct
     7681 agctgttggg cgatgattat ctgaagtcat aaatttcccc ctctttttat taatttaaag
     7741 tattagaata tgttgatttt agcacactat acgatatttt acaatgtaga aaataaatat
     7801 gtaaatttat atataaataa gctcttgatt tagatacaga tagatatttt tttagactgt
     7861 acattaagga ataactaatt tccaaaatat acctaaagaa agtaagtgat atttagttat
     7921 ataatttaag taaatatatg caatagttat ttttatatgt aaatatcaaa atattatgaa
     7981 cttatatttt atctattttt tacactgtat aaaaacttta tagttttgaa tactatataa
     8041 ttttaaatac gctgtatttt tgcatataag gaagtcattt gataatatac aaggtattat
     8101 cagaaagttt gaaaaaattt tgacaaaaat ttattttttt tattgactca taaataggaa
     8161 aatgctatca ttaattcaaa gattcgtaat taaaaactta gttcttaaat acgaaccgaa
     8221 acggccgtta gaattaaagc taaaaactta ataagagtaa ttaaatatca tgttttagga
     8281 ggattaactt tatgataatg gattttatta aaaaaattcc tgcaggtatg atgatagtgc
     8341 caatgtttat agcagctttc attaatacct tttgcccaga tattgtacaa ataggttcgt
     8401 ttacgacagc agtattttca agtgttgggt ctgcaactat aattggggtt caactggtat
     8461 gcttgggaac tcagcttcaa tttagagaaa tgccaaaagt tttaaagaga ggtggtatac
     8521 ttcttggttc taaatttgct ataggtgctt tgataggtat acttatagga aagctatttg
     8581 gaatggatgg tgtccttggt ctgacaacat tggctgttat aagtgcagtt acaaatagta
     8641 atggtagtat atatctttca ttgatgactt catatggaga tgaaacagat tgtgcaacta
     8701 tgagtttact tactttaaat gatggaccat tttttacatt aatagctctt gggacttcag
     8761 gtcttgcaaa tgtaccattg ttgtcattat tggctgcaat agtgccaata cttgttggta
     8821 tgataatagg aaattttgac aaaaaaatga aagagttttt agagccaggg tgtaatttac
     8881 tcgtaccttt tgtagggttt gcacttggta gtagcataaa tcttgcaagt atactaaaag
     8941 gaggtttatc aggagtatta cttggattaa tatctgtatt tgtaggaggt atatttatag
     9001 tattctgtga taaatttata ggaaaacgtc caggatatgc aggatgggct gtagctacaa
     9061 ctgctggaaa tgcaattgct gtacctgctg ctgttgcatt agttgaccca tcatggcaac
     9121 catatgttgc aacagctaca acacaagtgg cagccgcagt agttgtcact gcaatattag
     9181 tacctcttat aactagttgg tgggctaaga agtatggatg tcctaagttc ccaaaacaaa
     9241 atgaggatgg tacaataaca gcttaattta tattacagtg agttgttggt aaaataataa
     9301 attctttaat tagattttag gatattaata aaattatatt atttataaag gagagcaaga
     9361 ataatgataa atgcagtgat aattgatgaa aaagataatg ttgcagtagc tattgaagca
     9421 atagctaaag gtagtgaaat tagttttaaa ttaaaagaca aaacagtaaa aacgattaca
     9481 gcactagatg atataactat ttatcataaa ttggctataa aagatatggc caaaggtgat
     9541 aaagttacta aatatggtga acatatagga gaagcaaatc aggaaataaa aagtggccaa
     9601 catgtacata ttcataatgt tagaagtgtt agagaggatt tggataaaca agttatgact
     9661 aatatataaa ataatattta tagagttata aaagttgtat tcattgcttt tagtgtcaaa
     9721 tagtttttaa ataggttttt agctgtttga ttagtgagtg taataaaaat tataatatat
     9781 aaaaattata gaaagtatat agactatttt aggaggaaat cagtatgaaa ttttatggat
     9841 ataaaagacc agatggaaga gttggtataa gaaaccacat attaatattg cctacgagtg
     9901 tgtgtgcatc agatacaact agaataatag catcacaagt tcaaggggca gttaccttta
     9961 ataatcagaa tggatgttca caagtacatt cagaccaaca attaactatg gatgttatgg
    10021 ctggttatgc agcaaatcca aatgtatatg gtgtaatagt tgtatctttg ggatgcgaaa
    10081 attgccaaaa tgatttggta gttgatgcaa taaaagagag aacaaataag ccaataaaaa
    10141 ctcttgtaat acaagaagaa catggaactt taaaaactat agaaaaagct gttcgttatg
    10201 ctagagaaat ggcacaagaa gcttctttgc ttagaaaaga agaatttcca atatctgaac
    10261 ttatactagg aactgaatgt ggtgggtctg acccaacaag tggattagca gcaaatccat
    10321 taataggtga attaagtgat aaacttgtcg atttaggagc aacatcaatt ttaagtgaaa
    10381 ctactgaatt tataggtgca gagcatatac tagctaggag agcagtaaat gaagaagtaa
    10441 aagaaaaaat attacatata gtacatagat atgaaaattc attaaaattg gttggagaag
    10501 aagttagaga aggtaatcca tctcctggaa atatagctgg tggtttaaca agtttagaag
    10561 aaaaatcact tggttgtata cataaaggtg gtcatagaca aataagtgaa gtatatgatt
    10621 atgccaaaca aattgataag aaaggtcttg ttataatgga tacccctgga aatgatgctt
    10681 catctgttgc tggtatggta gcaggaggag cacaaatagt ggtatttagt acaggaagag
    10741 gaacaccatc aggaaatcca atagcaccag taataaaaat aactggaaat aaaataactt
    10801 ttgcaaatat ggaagataat atggattttg atgctagtcc agttatctat ggtccacaaa
    10861 caatggaaga attaacagat gatttgttaa atatggttgt agatgtagca aatggaaaac
    10921 aatcaaaagc agagtccctt ggatatactg aaatggcaat agctagagta tgcaactatg
    10981 tataatcttt aagtaagaaa ataaatacat agaattttaa taaagggtga gattatgaag
    11041 tttgtaagtt ttactgaagg agaaaatgaa tgtaaaagaa ctggagtttt ttctaaagat
    11101 gaattattta ttatagatgt taactcttta aatctcagta gaaattttaa ggatttaaat
    11161 gaattaattc aaaatgtatc tagtgaagat attattaagt tgaaaactat tataaatgaa
    11221 agtacattct ataattatga tgtttttaaa agagagagat gtacggtaca tgttcctata
    11281 gaaaaaccaa tacatgatat cttatgtgtg ggagtgaact ataaagacca tcttgaagaa
    11341 actcaaactc actttgatga tagttttgaa gaaccacaaa aaacggttta ttttacaaaa
    11401 cgtgtgacaa aggcaatagg tccagaagat gagatagatg gtcattttga gataaataat
    11461 caactagact atgaagttga acttggagta gtaataggta aaacaggtgt taatattaga
    11521 aaagaagagg tagaagatta tatctttggt tacactgtta taaatgatat ttctgctaga
    11581 aagttgcaaa aagaacatgt tcaatggttt agaggaaaag gattagatac atttacctct
    11641 ttaggtccat gtattttaca taaaagtgca gttccttttc ctataaaact taaagtatgt
    11701 agtagggtaa atggtgaaga aagacaaagt tctaatacag gattattcat atcagacgtt
    11761 tcagacatag tttcagaact ttcaaaaggt atgaccttag aggctggaga cattatagct
    11821 actggaacac cttctggagt agggatggga ttttcacctc ctcgatatat gagtagtgga
    11881 gatgtagttg aatgtgagat tgagagtatt ggaattttaa aaaattacat taagtaactg
    11941 ttttaatata attaatatta aagctaaatc tgatgtatta atgaacatat taaaataaat
    12001 tttaggagtt taaattatga aagcagaatt tttgacacca gttgttacaa tatttgatga
    12061 agaaggaaat ttagataaag aaggtaataa aaaagtgtat gaccatctta tagatggagg
    12121 tgtagatgga ctagtcataa tgggaagtac tggagagttc tttaatatgt ctatggatat
    12181 gcaaaaagaa cttatagatt tagtaactag tcatgtaaat aagagagtaa aagtgtttat
    12241 aggtacaagt cgtatgtgta taaatgaatc tatagaactt tcaaactatg cacataatag
    12301 tggagcagat ggtgttatga taataagccc ttattatttc tctcttgatg atgatagtat
    12361 tgagttattt tatagtgaaa tagctaagaa tacagaggct gaaatatatt tgtacaatta
    12421 tccagataga actggttatg atttaagtcc agaacttaca ttaagacttg caagaaaaca
    12481 taaaaacata gttggatata aggatacagt aactttgatg ggacatacca gagatttaat
    12541 aaatactatg aaaatagagt tcccagaatt taaggtttat agtggttatg atgaaaactt
    12601 tatacataat ctaatgtctg ggggagcagg ttgtataggg gggttatcaa atttaattcc
    12661 agaagtttgc tccaaatggg ctgaagctta caataataga gatatggaga aggttataga
    12721 aattcaaaaa tatattaata aagcaatgga tttttactta ataaccaatc catttatacc
    12781 agcaatgaaa aaagctatga atatcagagg gttacaaata agtgattata tgactgctcc
    12841 atttgtaaaa ccaaatgaaa aacaagtatg tgaaattaaa aaattgatga atgaattaaa
    12901 tatatgttaa atcaaccttg caaagaggtc aacaataaat tacaattatc ttaataaaaa
    12961 ttaaattaaa ataatactag ggtactatat tagtttaata gggaaagtga tgaaaattca
    13021 ctacagcccc cgctactgta tacggatacg aaatcaaaat ccactgaaat ttataaaaat
    13081 tttgggaagg gtgatggagg aaaagccgtg agtcaggaga cctgcccagt attatataag
    13141 ttcaatttag ggtggagatt gtaatttata ataaaatgaa gtatcaattc gtttttgtaa
    13201 agttgatata tgaacttctc cttattaaat taggagaagt tttttatttt attaaaaggt
    13261 tatacttatt aaagatgact ttaggataac tttaataagt atactttaaa aagcatatat
    13321 tattaaagtt ttttagccac tcataaaaaa taagatattg gagtgaaaga gatgaaattt
    13381 aaatcaaatg ttttaaagca gtttttttta attgctatgg taatttttat ggtaggaggt
    13441 cttatagggt gtagtaaaag tgacaaagag aataaacaag ctagtactgg taagaaatta
    13501 gaattaaaat atgctagtgg atttagtgtt gaagatttag aagatggaat taaaaaagta
    13561 actgatggag ataatcgaga actgatttta atcccaaaga agattaaaat tcctgaaaaa
    13621 tataaaaatg ctaatatagt tagaacgcct gtggacaatg tattaatagc atctacaaca
    13681 caggcttgtt ctctgagaac aatagatgaa ctagatagta taaaagccgt aacaacagaa
    13741 gagcagtact ggactattaa agaaattaaa gatttaatga aagatggaaa aatacattac
    13801 gttggttcaa atttagcacc agattatgaa aaaatagtag acttaaatcc tgacttaact
    13861 atagtgagta gtggtttatc agaggctgat acaaaattta ttgacaaatt aaaagaatta
    13921 gggcttaatt atgttgtaga caatgagtat aaagagcaaa atccatttgg aagaatggag
    13981 tggacaagtt taatagctgc attttatgat aaagaagata tggctactag tgaactaaat
    14041 aaaactgtac aaaaggtaga agaagtaagt aaaaaaataa aaaacaaagc taaacctaaa
    14101 gttgtatggg catctgtata tgaaggaagt gcttatatag ctcctaaaga ttcatatgtg
    14161 gataatatga taaaaatggc tggtggaata aatgcatgtg cttcaataga ttcaaatgaa
    14221 gggcgagtaa gtattgaaca attgcatgaa gttgcaaaag atgcagatat atttgtatac
    14281 tcatcaagtt cagattatgc accaaattta gattctataa aatctagtgc acctgtattg
    14341 gctgatttgg atgttgtaaa aaacgggaac ctatgggtgt ttgctccaga ttattatcaa
    14401 tcagtagata agacggacga attaatagta gatttagttg agatgttcca cccaggtact
    14461 acaggtgaaa aaatcaaaca ttatataaat tatgataaat agtacagaga ggacacaaaa
    14521 agataggttt tatagatttt agttaatata gctttgctaa gaggagtata caaatggatt
    14581 ttatcaataa aatgagaata aggaatacaa caatatttat agtattaatt ataagtatga
    14641 tacttacttt tttagtgtgt gtagcatttg gctctgtaaa aattgaattt aaagaagtaa
    14701 tagatgttgt attaagaggt atggataata cagaacatta taaaataata tacaatataa
    14761 gaatccctag agtacttgca accatggtag gtggagcatg cctagcagta tcaggtattt
    14821 tattacagat attttttaaa aacccaatag ttgaaccgta tatattagga gtatcttcag
    14881 gttctacttt atcagtagct ctcatgattt tgggaggata cacattggga tttgagagtg
    14941 taaattcaat gagtatattt gtagcagctt ttataggagc tttaattgta atgtctatag
    15001 tcattttatt tgcaaataag gtaaagaata taacaactct tttaataata ggaattatga
    15061 ccggatatgt atgtagtggt ataacaaatg tgttacaatc atttgcaaat agtgataaat
    15121 taaaagaatt tactatgtgg tctatgggaa gtttttctgg atttacatgg gaaaaggtag
    15181 aaatacttat aatagttggt atattaggtc ttttgatgac tgtattcata ataaaacctt
    15241 taaatgcttt tttactagga gaagagtatg caaaaagtat tggcataaat ataagatttt
    15301 ttagagtttt gatagtattt atatctagta tattagcagc aatagtatca gcatttgcag
    15361 gacctatagg gtttattgga cttgcagtgc cacaaatttc aaaaatgata tttaaaacat
    15421 cagataatag agttttgata ccagtagtaa tatttttagg cagtatagtt acagctcttt
    15481 gtgatttaat atcaagagta attttatcac cagtagaatt accaataagt acgataacat
    15541 ctttattagg agctccaatt gtagtaatgt tattggtgaa aaggaaggat agggcttaga
    15601 catgttgaaa actaataatt taagtgtagg atacaataac aaagttgtta taagtaatat
    15661 aaatgtagaa gtaaaaaatg gagaaatact atgtcttttg ggaagtaatg gagctggaaa
    15721 aactacccta ttaaggtcct tatctaaact tatatcacca ataaaaggtg aaatatattt
    15781 gaatggtgta aacataaact gtatatcaag aaaagcatta tcaaaaaaaa tggctttagt
    15841 acttacaaat agattattag gtgatttaat gactgtacaa gatatagtca atataggaag
    15901 gtatccatat acaggatttt ttgggagtct atctaagaaa gatttaataa tggtagatga
    15961 agcattggag tctgtagatg ccttacattt aaagaaaaga tattttgatg aactaagtga
    16021 tggagaaaaa caaaaggtgt tggttgcaag ggctcttgtt caagaaccag aaataattat
    16081 attagatgag cctacaactc acttggatat aaaacataga ttggaactca taaacatact
    16141 gaaaaaatta agtaaagaaa agtcaatatc agtaatactt tcattgcatg aaatagacat
    16201 agcattaaaa agttgtgata aagttgctct tataaaaaat aataaagtca tagcttatgg
    16261 tcagcctgaa gatgtagtag atgaggatat tataaattcg ctttatgaat tggatgataa
    16321 aaactttaat agtcttttag gttcagtaga aattagtaat aaatctaaaa atgaagtttt
    16381 tataattggt ggtgggggta aagcaacacc aatttataga gcttttacta aaaaaggtat
    16441 aggtctgtat tctggaataa tacatgaaaa tgatattgat tatgaaattg gtagaactat
    16501 ggggataaag atgtttacag aaaatccatt tgagcctata agtgatgaga gtttcgattt
    16561 ggctattaga aatttaaatg attccaagat tataatagat acaggattta gtgtaggaga
    16621 gacaaataag aggaatatag atattataaa agaggcttta aaattggata aaaaagttta
    16681 ttcttttaga aatagagatg agagtaagaa gtattatgac agtttggata gtaagataga
    16741 acatatagat aaagtttctc aaataatcaa tagtgcagat ataaataatt tattataatt
    16801 tatgaaataa aatgtactta tgtgctatag aaaaaagagt atagattata atttttttga
    16861 aattacaatc tatactcttt tgttattttg tttatgtatt tatatattta taaaacttta
    16921 gcattttata gataaccaat agcttcctct ctagttaaaa aaaagtgaat ccctgtagtc
    16981 gattctttcc atctattttc attaaaatct tcagctacaa tcgtttctcc tactctatat
    17041 ataaaatttt catcagcata tgcacgagca cttttaaaag attctttacc atctatacta
    17101 gtaattgaca gtacttttgc cttatcacat ctacaagcgt ttgatgtagc agacactctt
    17161 tttgcgtcgc tgggtattaa taattgtacc attctaaaat taaaacattt tttatagcct
    17221 ataaatgctc ctgtttcagg acaatacaat ttaaaaaaac gggtactttc atctgatatt
    17281 actccattta aagtagcatg ttctaaattt gaattttcta aattagctcc tctaatatct
    17341 gagttagata agtcacaaaa tctaaaactt gcaccactta agtctgcatt ttttaatata
    17401 gaatttttta atgaacaatc cgaaagataa gaattattaa aaatagagtt ttctaaatct
    17461 gctttttcta aatttaaatt gataaggtca gaccacgaaa agtcaatatt acttaagcag
    17521 tatcctctta agtccatatt ttctaatctt aattctttta aatctgcctt ttctccagca
    17581 ttattgtttt taagccataa ataatgtttc tcaagtgttt tttctaattc ttgtttagaa
    17641 atagttttca ttaaaatcac cttcataaat ttatttttat atatgtagta gcaaaatagt
    17701 catatattta attatataac aataaataaa aaacttctaa ataatatata aaatatcatc
    17761 ttgaaagtac ttttttcaat atatcagaat atatttttaa gctatttaga gataatttaa
    17821 atttttaaac aggacataat aagcttgtat tgttttatat ttgagttgat aaaaatttct
    17881 ttaaataaaa ataatgtcaa ttataaagta ataaaagttt agatataaaa aaatttgtgt
    17941 atatactata tgtagtatat aatagataaa gcactgacta tatgtagtgc ttttgttttt
    18001 gaaaaatact tattgcattt ctataattat agattaattt tgggatttca actgataagt
    18061 accaaaagaa ataataagca aattaagtga aattatggca caagattatg ttaaaaggac
    18121 ggtaaataat gaattggata gagcttaaca atcaagtgat aattaaaaat gaacaaggca
    18181 agtaccaatt ggaaaaggat aaggaagcct taagtagtta catagaagaa tttatacagc
    18241 caaagttgag aaaatttaat aacctagaag aaagattgaa gtatttaata gatgaaggtt
    18301 attattcaaa agaagtaata aatcagtata gcatagatgt tattaaaaat atatatgata
    18361 tgattgataa acataagttt gaatttcaat catatatgag tgcaaataag ttttatcaaa
    18421 attatgcatt aaagagcaat gatggaaagg aaatattaga aacatataat gataaagtgt
    18481 taattgtagc tttgacacta ggaaatggtg ataaagattt agctttaaac ttggcagata
    18541 aaatagtaaa acaagaattt caaccagcta cacctacttt tttaaatgct ggaagaaaaa
    18601 gggctggaga aatggtatca tgttttttac tatctgtaga agatagtaca gaaggtatat
    18661 catatgctat atcttcatca aatcacttat caaagattgg tggaggagtt gcactaaatt
    18721 tatctaaact tagagcatct ggcgaatcta tcaaagatat agaaggtgca gctggaggtg
    18781 ttgttggagt agctaaaatg ttagaacaat catttagtta ctttaatcaa atgggagcta
    18841 gacaaggttc tggtgcggtg taccttactg tattccatcc tgattttgaa ttgttgatgg
    18901 atactaaaaa gataaatgca gatgaaaaaa taaggcttgc tacattatca ttaggagcta
    18961 taataccaga taaatttatg gagttggcag aaaaaaatga agtagcatat gcattttatc
    19021 ctcatactgt gtataagaaa tatggagttt ctcttgatga gatagaaatg gatgagtggt
    19081 atgataaatt ggttaatgat agtgatataa gaaaaaaaga aataaatcct aggcagatgt
    19141 tgacaaaaat agcacagatg caacaagaaa gtggatatcc atatgtagtg tacatagata
    19201 cagctaatag agaacataca ttaaaagatg ttggaattat taaaatgtct aacttatgtt
    19261 gtgagatatt tcaatatcaa acaccttcag aaatagaggg gtatggagga aaaaatgaat
    19321 ggggacaaga tataagttgt aacctaggtt ctttaaacat agctaatgta atggataata
    19381 aaactataga aagtacagtt gaaacagcaa taagagcact gtcatttgta gcagatagca
    19441 cagatataaa accagtgcca acggtaagca atagtaacag caagtctcat tctataggat
    19501 taggagctat gaatttacat ggatacttag taagagaaaa tattttatat acttcagatg
    19561 atgctataga tttttctaat gtattttttg caatggttag atactattca attaaagctt
    19621 ctatgaaaat agctatagaa agaaatcaaa cttttgaagg atttgataaa tcagaatatg
    19681 ttaagggaag aaatagcaag gttttatcaa aatactatga acaatcttat ctacctaagt
    19741 cagaaaaggt aagagcatta tttgaaggga tttatatacc aacaaaagaa gactggacaa
    19801 aattattgga tgaggtaaaa gaaaaaggga tatataatgc atatttaatg gcagtagcac
    19861 caactcaaag cattagttat gttcaaaatg ctacatcaag tataatgcca attactgagc
    19921 cagtagaagt aagaacatat ggagactcta ctacaatata tccaatgcca tttttaacaa
    19981 atgataatat gttgtattat caatcagcat acaggatgga tatgagaaag gtcatagatt
    20041 tagtggcaac agttcaaaac catgttgacc aaggtatatc aacaacactg tttgttacag
    20101 atgaaaagac aactagagat atagctagac attacatata tgcctataaa aaaggtttga
    20161 aaagtttata ttacacaaga acaaagatga caagagatac tcatgagtgt ctagtgtgtt
    20221 cagtataggg agagaaatta tgacatttaa tttacataaa atacataatg cagttaactg
    20281 gaatagagaa gaagatggat ttacacaagc tttttgggaa caaaatgtaa aacaattttg
    20341 gcttcctgaa gaaatatctg tttctaaaga cataaaggta tggaatgaac taagtaataa
    20401 agaaaaggaa ttatataaaa aagtattggg tggtttaaca ttactggata caaaacaggg
    20461 gaataatgga ataccatcta tgatgagttt aacagaaaac ctacaaagaa aagctgtctt
    20521 gtcttttatg gggactatgg aagaaataca tgcaaaaagt tattcttcta tatttatgac
    20581 tctactttct aatttagaaa tagatgaatt atttgaatgg atagaaacag aaccaacatt
    20641 acaaagaaag gctgatttag ttttagctca atacgaaaat actacaaatc aagagggatt
    20701 atacctatca atggttacaa gtgtattttt agagagtttc ttgttttatt caggattctt
    20761 ttatccattg tatctatctg gtcaaggaaa gatggtagct agtggagaaa taatatcgct
    20821 tattcttaga gatgagtctt tacatggtaa gtatatagga ttgctagcac aagaaatata
    20881 cgattcattt gataaaatgg ataaggagat gttagaagag aagatgtatt ctatacttta
    20941 tagccttatg gagaatgaga tagagtatac aaatgttata tacagagaaa gtgggcttga
    21001 aaaagaggtt gtgaactttt taaaatacaa tgcaaataga gctttagaaa atctagggtt
    21061 tgagaagcta tatactgtag atgctataaa tccaattgta ttaaatggtc ttagcactga
    21121 aaccaaaaca catgattttt tttcaactaa gggtaatgga taccaaaaag gagtgtatga
    21181 ggaattagag gatgaagatt ttataatata atttataatt atgacacact gttgtcactt
    21241 ttagcgtgat aatatcaatg tataaaatat atatggaggt atttttatga aatatgaatg
    21301 gagaaaaaga gataaagagt tatatttacc taaaaagaat cctgtaatag ttgaaatacc
    21361 agaacagaaa tttatcatgt taaaagggag tggagaccca aattctaaag aatttactga
    21421 agcaatagga gtactttatt ctttggcata tgcaataaaa accatgccta aaaaaggaat
    21481 tgtaccagaa gggtattttg actatacggt ttttccttta gaaggtatat gggataaggg
    21541 agaaaaaagt aaaggcttag atgtacttat taaagaagat ttaatttaca ctataatgat
    21601 acgtcagcca gattttgtta cacaagacct gttggataaa gctactgata tagtaaagaa
    21661 gaaaaaacct cataatcttc ttgaaaaagt tagatttggg tctattaatg aagggctatg
    21721 tgttcaaatg cttcatatag gttcatatga taatgaacca gaaagctttg acattatgaa
    21781 cgaattttgc aaaaaaaata aacttataag aaaatcttac acacatcgtg aaatttatat
    21841 aagtgatgct agaaaagtat cgcctgaatc attgaagacg gttttacgtt ttgaagtaga
    21901 aagggaagta taaatatttt gaataattta taagagttat aaaaagtgaa gtctgttgag
    21961 acttcatttt ttgatgcaat tttaaaatta aatttgatgt ttcataatat tttaaaaact
    22021 ttctactttt attagtgtga ataactgttg ctattaaata ataatactaa ttatataagt
    22081 attattatat aatatttata gattattata taaatagatt attagtaaga tgtatgcatt
    22141 attaattaaa ataaattaca tatactattt aatatttcat ttaaaatatt aaaaaatgta
    22201 gataaaaatt gttttattaa gaaaaaatta atatattgac aaaatttaag tgctcattta
    22261 aactattaat tgataataat attcaatatt aaataatagg aggcgttatg aataaatatc
    22321 ttctaataaa tccagtggca gaaagaatgt atggagaaaa gtttcacctt attaaagcaa
    22381 atttgataaa aaaggggtac ataataacag aatgtgaacc acagttagaa tatgtaaaaa
    22441 agcagtacaa agagtataca aaaaagactg aaaatacaat gttggattgt agatgtccag
    22501 aaagtataag tcttttaaaa agaaataatt tgataaataa ttttgaagta cctatgatag
    22561 aaccaatatt agtaaggact tgtagggttt tatacgataa atatataaaa agtaaagatg
    22621 atatgttggt agtaacctgt ccatgtacac aattaagaga ctttgcaagt gaaaagttta
    22681 aggataaggg taatgctatg ttttatacat ggaaagagtt tgctgaacaa gaaggtgtaa
    22741 aatcacttgg aaaaatagat gaatcaccaa ttccattagg atatttcaaa gatacttttg
    22801 aaaaagttct tgaagtatca agtgaagacg aaatattaag tgaaatacaa aaaataagaa
    22861 atggttttga agataagtat gacatagtag aaatgtttta ttgtaaagat ggttgtaata
    22921 atggagatgg tttgtaaatg gtcaataaat ttaataataa gtttttaagg ctagtaaaga
    22981 gtgttctgat attttttata attcttttat tatggaaaat tacaaattat cttggtattt
    23041 ggagtgatta tatattacca tcacctgaaa aggtatatag tacattttta aatatgataa
    23101 gtgatggttc aatatttatt aatgtatatg caagtatgaa aagagttttg ataggttttg
    23161 caataagtac tgctataggt gtgcctttag ggatattctt tggaatttat agtggagtat
    23221 acgaatactt taaatctcta ataaattttt taaggaatac acctcccctt gctttaatac
    23281 caatgcttat attatggttt ggtataggag aggaatcaaa aattataatt atagttttag
    23341 catctttttt cccaatcttt acaagcacat tgaaagggat taaaaattgt gactcaaaac
    23401 tgattgaagt gggtagagta tttgagtttt caaagcttca gataatattt aaaataataa
    23461 taccaaatgc cattcttgat attgctgttg ggttaaagtt agctcttgga tatagcttta
    23521 gagcaattat tggggcagaa cttgtagcag cttcatctgg tcttggatac ttgatatctg
    23581 atggaaaaga aatgtctaga acagatgttg ttattgtagg gataatcgta attggacttt
    23641 taggaataat tacagattac atattttcga ttattgtgaa gaaggtaagt aagggaaaga
    23701 tggtggaagc atatgaataa tttagtatgt gactctggat atataattag aaatttatat
    23761 aaaagttata aagttgacaa taaagaacat gtagttctta gtgatatctc tttaaacata
    23821 gatagaaacc atataacagt aattttaggt gaaagtggtt gtggaaagac taccttgctt
    23881 agagcaattg catcacttga aggtataaat agtggtgaaa ttaggtttat taatgataat
    23941 aaagagtata gacctaatgt tggttttgtt tttcaggaga gtagattaat gccttggtta
    24001 aacgtaagtg aaaatatagc ttttcataat caaagaaaaa atactatttt aaacaaggtg
    24061 cttagaaaat ttaaacacaa taaaagaatt aggagtaaaa ttataaatga taattttaga
    24121 agcttagaaa caaatgataa tttgaacaaa tcaaataaat ataataggaa aagtaatatt
    24181 gatgtagaaa aatatcttaa gatgatgaac ttgcagaaat ttaaaaactc ttatccaaat
    24241 gaattgtcag gaggtatggc gcagagagta agcatagcta gagctctttc tttcaatcca
    24301 gatatgttgc ttatggacga gcctttttcg gcattagatt attttacaag gattgatatg
    24361 caaaatgaag ttataagaat acataagtca actaataaag gcgtgatatt tgtaactcat
    24421 gatattgatg aagcgttaaa gataggcaag aaaatagttg ttttcacaga cgaaagaaaa
    24481 gtaaaagaat ttaatataga agatggttat aatagagatt taacttcaga ttactatatt
    24541 aaattaaaaa aagatatttt aatgacaatg aagtcaaata aaggcattta aagaaattaa
    24601 taatatttta aggagtaaag taaatgaaat taaaaaagct attgataggt ataacgatat
    24661 taacacttgc aacagcatct ttagctggat gtgctaaaaa aaataatgga gaaaaacttt
    24721 cagaaataaa tttaacttat gtaaaatcac cattaaatgt tccttctata attcagaaac
    24781 aggatgattt atttggaaag gaatttaaaa aggataatat aaaagttaac ttccacgaaa
    24841 ttactacagg tccagagcaa acacaagctt tagctgctgg agaaatagac ttcttacatg
    24901 cactaggtgg tacatcagct ttaatagctg catctaatgg agtagagtta aagatattaa
    24961 acacttatag caggtcacca aaaggattta tgattttgac taataataat tcaataaaat
    25021 cagcagcaga tttagtaggt aagaaggtgg caggcccaaa agggactata ttacatcagg
    25081 tattgatttc agcacttgat aaagaaggat taagtatgga tgatgtggaa tttgttaata
    25141 tgggtattcc agaggcatca gcagctcttt ctgatggcag cgtagatgct gcattgattg
    25201 ctgggccagc agctcttaaa gctatgaagt caggtagtaa acttgtagca aatggtgaag
    25261 gtttagtaga tggtataata gtaactgctg ttagcacaga ctttgcagag aaacatccag
    25321 aaatagttga aagatttatg aaggttgaaa aggaaacttt agaatatgta aataataatt
    25381 ttgatgaagc tatggaaaaa gtagctaaag aagttgattt aagtcttgaa gaaactaaag
    25441 aattatatgc ttggtatgat tttagtttag atataacaga taaagacata tcttcgcttg
    25501 aagatacaca agacttctta ataaaaaata agttacaaga gaaaaaagtg aacataaaag
    25561 aattaatcta taatgctaag tagaaactat gataaaataa tactaagtaa gaaatataat
    25621 aaaagtttaa gttaccttat taaggtaact ttttctattt tgaattagta atttcaattt
    25681 attttagaat gattagttga taataatgat taattaatca taaaaagata cttttttata
    25741 gagttttatt aagatgtcta ataatatggt tatacttatg aagtcagtaa ttgtgaagtt
    25801 agtaatatga ttaaatttat atattgtaaa aagattataa tatattaaaa ttggactgtt
    25861 atatgatgag taaataggta tattaggagg aattatatga gttataaagt atatattgtg
    25921 gaagatgaca tatcaataag tacattactt aaagattata ttgagaaata tggatttgaa
    25981 gtgattgttg aagagaactt tgatgatata atgattacat ttgaaagttt taagccacac
    26041 ttagttctat tagatgtaaa tttacctaaa tttgatggtt tctactggtg tagatgtatt
    26101 aggcaacagt cgaatttacc tataattttt atatcagcta gagatggtaa tgtagaccaa
    26161 attagagctt tagaaagtgg agcagatgat tatataacaa aaccttttta ctatgatgta
    26221 gtaatggcaa aaataaagag tcatataaga agggtatatg gtgaatattc acctaaaata
    26281 gacgaaagaa tagtggagct agatggatta aaattttatc cagaaaggtt agaactagaa
    26341 ttaaatggtg agaatctaat tataactaaa aaagaaggta tactgattga atgtcttatc
    26401 aagagatacc caaaagtagt aagtagagat tatcttttag aaaagatatg ggatgatatt
    26461 gagtttgtag aggaaaatac tttaaatgta aatgttagca ggataaggaa aagatttgag
    26521 gaattaggta tagataatgc tgttcagact gtccgagggt taggatataa attaaataag
    26581 aattggtaag gagaaagtat gaagttattt ttaaaagatt ataaaggtta tatttttata
    26641 tattatatag gcatagttat gacaattatt tactgtaatc ttatgaagtt tattagtttt
    26701 ggagagagtt tatatattct tttatttagt tcttttatat tgttatgttt tttaatatat
    26761 aagtattata aaaatagaga agtatataat ctgtttgaaa aaggagtaca ttctttggag
    26821 gagtcatttt tgtatttagg aagctcattc ttggggagaa atatatcagt tattttaaaa
    26881 caacaacata aattgtatca atcaatgata caagagcata aaaagataca tagtgaacat
    26941 ttaactttca tcaaccaatg gattcatcag atgaaaacac caatatcagt tataagcctt
    27001 cagctccaag attatgaggg agaagaagta actgaaaata taagaaaaga aatagataga
    27061 ttgaataaag ggttagatat ggctatgcat tttgcaaggg cagataattt tcagaaagac
    27121 tttatagttg aaaaagccaa attaaatgaa attgtatcta gtattgtaaa tgaagaaaaa
    27181 aggttattta taaaaagtgg aatgattcct aagattcaag tagacaagtt tacttatgtt
    27241 tatacagatg taaaatggat gaaatttata ataggtcaat taattacaaa tggagtgaaa
    27301 tattctaaag attatagtaa ctacctaact ataaaatctg aagaaaataa taaatatgta
    27361 attttaagta taatagatga aggaattgga attgtttcta aagatttaaa aagggtattt
    27421 gccccatttt ttacaggaga aaatggtcgt aagtttggag aatctacagg tatgggtctt
    27481 tatctagtaa aaaaggtatg tgatgattta ggtcataaag taagtataaa atcagaagta
    27541 ggaaaaggta cagaagtttc aatctacttt aataaaggtg taaatagttt gataaagatg
    27601 taaattatct gttacaatag ggtttttagt taattgtact tttttattat acaatttatt
    27661 aaatgaaata ttcatagtta aataatcaaa atttaagaga gtttatttgc aaaccttaca
    27721 tagatgtaag gtttgtgtaa tgtttgcaga tagttaaatt ttctaatcta aattacaatt
    27781 aatataagaa ataacataag agaaataaca taaaaaaaga aattttgtaa aaaaggaagg
    27841 atgtttattg atgagtttag atgttatttt tatattgaaa tcagtcataa tagctatagt
    27901 agaggggctt acagaattta ttccagtttc atctacaggt catatgattt tggttggtaa
    27961 tttaatagat tttaaggggc aatttgctga aatgtttgag gttgtaatac aacttggggc
    28021 tatattagca gtagtagtac tttattggaa aaagataaaa gatagcgtta tagaattttt
    28081 taaatttata tttactggtg gaaaagaagg aaagattggt tttagatttg gaatgaatgt
    28141 aattataggt tgtataccat ttgcgattat aggagttcta ttttacgata atataaaatc
    28201 attgtttaat ttacaatctg taattatagg atttatagtg ggtgggattt tattattagt
    28261 agtagaaact ttgtttagaa aaaagaatca ttccacagat aatatagata aaattactcc
    28321 aatacaagct ttaaaggttg ggacattaca agttttgtct gcatggccag gtatgtcaag
    28381 gagtgcatct actattatgg gtggatggat agcaggactt aattctccta cagcagctga
    28441 gttttctttc tttttagcag taccagctat ggtggcttct tcaggaaaag atttatttga
    28501 atttgattat tcaataatga caccaacatt gtggattgct ttggtagttg ggtttatagt
    28561 agcttttatt gtatcaataa tagttatgga aaaattcgtg aattttttaa agaaaaaacc
    28621 aatgagagtg tttgctgtat acagaataat catgggtgta gtacttgcag tattagcttt
    28681 tactaacata attagtgtat agaaaaaata gatttattat ctataaaaat taaactaaga
    28741 taaattataa ttaacaatta tatatatgtt atttcaaaaa ttaaattagg aaggatagtt
    28801 aaataatgaa aattttaact gtaaataatt taagtaaagt atatggtaaa aaaataattt
    28861 tcaacgcatt aaatgacata aattttagta tagaagatgg agaatttgta ggaattatgg
    28921 gtccatctgg tagtggaaaa actactcttt taaatatgat ttctactatt gacaagccaa
    28981 ctacaggaac tatggaatta aagggcaaga atcctttatt gttaagaggt gaggaacttg
    29041 cattatttag aagaagagag ttaggttttg tatttcagga ttttaattta ttggatacat
    29101 taactatagg agaaaatata gtattgccat tgacattaga taaggtcagt gtaaaagagc
    29161 aagatgagag attgaatgaa gtatctacaa tattaggtat aaaagattta ttaggaaaaa
    29221 gaacttttga agtatcaggt ggtcaagctc agaggactgc tattgctaga gcattgatta
    29281 acaatccatc aatactttta gcagatgaac caacaggtaa tttagattca aagtcatcaa
    29341 aggttgtaat ggagctattt caaaagataa ataaagaaaa taaagttact actatgatgg
    29401 taactcatga cccattagca gcgagctact gtagtagaat cttattcata aaagatgggt
    29461 ctatatataa tgaaatatat aagggtagta gtagagagca gttttatcaa gagataatgg
    29521 atgtacttac attattggga ggcgataact aatgaatata aaacagtttg ctattaacaa
    29581 tatttcaaga aatattaaag cgtatttagg atacttagca agtattgtta tatcatcttc
    29641 actgctattt tcttttatta tgtttacaag tcatccagat ttagatgtat ctcaatttcc
    29701 tgattattta aaagaaggtc tcaagatgag taagataatt gcatatctat tcttattctt
    29761 ctttgtgttt tattcagtta gtgtgtttct taaaagtaga tataaagaat ttggaatact
    29821 ttatattaca ggtatatcaa agcgccaagt aatgaaatta atctttatag aaaatatgat
    29881 aataaatata gtatcttctg taattggaat aataataggc ttaatctttg caaagatatt
    29941 tttagtggtt atgtctactt ttttagaatt atcaccatta aaattctata taccatttaa
    30001 tgcgatattg tctactttaa tctattttat gattttagct gtattaacat caatatttac
    30061 ttcttttata gttaaagaaa atcaggtgtt gaagttactt aaaggtacaa aaactccaaa
    30121 accagagcct aaaacatcac taatgcttgc tatattaagt atttgtttgt ttataatagc
    30181 gtattataat gctattacct caaccgacca atatacaaca tatctgcgct tagttccagt
    30241 tacatccctt actatagtag caacttactt gttcttttct caatttagtg tattttttat
    30301 gaagaagcta aaattaaaca agagatttta tagaaaaaat acaaatatgc tttggatttc
    30361 gaacttgatt tataaggtaa aggataatgc tagaatattt ttcttgataa ctataacttc
    30421 tgcagtggca tttactgcta taggtacagt ttattccttt tggaaagatg tagagcgtca
    30481 aattaattta atatatccta acacaatata ttattcaaca atgacattgc ataatgaccc
    30541 taaaaagcct gatagcaaag aaaaagacaa ggaaagaatg atgtttatag aaaataatct
    30601 aaaaaaagag aatgtagact atacaaggat taatggtgaa tttaaaactg tatttcccaa
    30661 gaaaagtgat tttaatgtca gaattatgaa agaatctaag tacttagaaa ttacagaaac
    30721 tataggggtt aagcctataa gttttgaaga taatgaatgt atatcattat tatcatcaag
    30781 tttaccagga aataagaacg tcaaagaaaa tattattgta gggaatagag gtttaaaggt
    30841 ggcaaaacaa gtggaagaat gtgttatgcc agcgtattac aaaaatatgt atgtggtaaa
    30901 ggataatttt tatgatagta tagaatcaaa atttatagtg gatagattta ctgcatttga
    30961 agtagaggat tcaagtaaaa ctatagagat atgcagagaa tttgaaaata aatttaataa
    31021 tgagtcaggg atgcaaccat atttgttttt ctctaaagaa ttaatgatag gaactgggaa
    31081 attaatgtat tctacattta tatttttagc aatatttata ggtttaattt tctttgttac
    31141 tacaagtagt tttttatata ataaatttta tatggattgc caagttgata agaaaaagta
    31201 tgaacagtta aataaattgg gtatgacata taatgagatt aaaaaagctt caacaattga
    31261 gattggaata gtatttttgt ttccttatgt agtggctgtt atacattcaa tatttgcact
    31321 tactgcactg aaaaattctt ttgatataga agtagcatca tcagctgttt tggtaatggg
    31381 aagcttgttc ttggttcaaa tagtttattt tttaattgta agaaataatt atttaaaaga
    31441 gataaggtta aatttagtca atttttagtt actattatta aatgataata aaaagggttt
    31501 agaattaatt aatattactg gaattataga tgtttatttt ttcagtaata ttttttattg
    31561 tattaactat taaaattttg tacaaatata aaatataata tggtaaatgt caaaattata
    31621 aaaaaattct acttatataa aatataaaga ggttatatgt acatatgtgt agaaataaat
    31681 aataaaaata tcaattaatg ttattagggg gggttactca ttagtaaatt agctaataca
    31741 cttagaatga tgatattaat tcaaagcaga ggcaaaatga aatgcaaaga attatcagaa
    31801 gagttggaag taagtgaaag gcaaataaaa agttacaaga tgtatttaga gcaagctggt
    31861 atatttataa attcaacacc tgggatttat ggtggttatg aaatagataa atgtaatagc
    31921 atctcattaa ttaaattatt agatagtgaa gtttcaattc tagatatgat aaattcacag
    31981 ttagagtata ataatgatat ttacaaaaat gaatttaata atattgtaga aaaaataaaa
    32041 gcagtattaa atacaggaga aaaaagcgat acatatatgg attattttac agttcaagca
    32101 caacgtaatt gtgattatga gtctgaaaaa aataagtgta atgaaataat tagagcatat
    32161 accacaaaac acaaattttg gatagaatat tattcattaa attcaggaaa tagtgaaaga
    32221 attgttcatc catatggttt atttaattat aaatcagata cttatatggt agctttttgt
    32281 gaaaaaagat ttaagtttat agactttaaa ttatgtagga ttaaagatta taaggtttta
    32341 gaagaaaaat ataatgtaga taaaagtttt agttgggatg aatatagtaa aaatagtata
    32401 ggaatttata agggagaaga aattaatgtt gttataaaaa ttagtcatcc attttcaaca
    32461 attataaagg agaaagtttg ggttaataat caacaaatca tagaatatga tgataaatct
    32521 ataatgttta aagctaaaat gagaggttat gaggagataa aaagttggat tttaagtatg
    32581 ggagcttatg ttgaggttgt agaaccagat agacttagaa atgatatatt gttagagatt
    32641 gaaaaaatga aaaaaattta ctgatttttt caaataattt atacttggac caatatactt
    32701 cacggtctag tgttaatata ttaattgaga gaggtgatat tatgaaaatg aaaattgaat
    32761 ttagtacagg ttgtatacca atatcttata attcgctctt tatgagtatt ataaaagaag
    32821 caataagaaa atctaatgaa gattactata aaaacatgta ctattataaa gaaaagaata
    32881 ataaaaaaac taaaaatttt acattttcgg tttatataaa aaagtatagt attgaaggtg
    32941 acaattttat tatagaagat aaagtaatat taaatataag tactccagat ttagaattgg
    33001 gttttcatat atacaatggg ttaatgactt ctaaaaaatg tttatataaa gactacgaac
    33061 ttacaagaat tagaatcgat ttatcaagag aaaagaaggt aacagaagaa agggtactat
    33121 ttaatgcatt gtctccaatc tgtgtaaagt ctaaagaagg aaaattcttg gagataactg
    33181 atgatagata catagaagaa ctaaactata taactaatga agtggttaaa aattataggg
    33241 ggaatggatt aaaaagaaag ttagaatttg aaaatatagg tctcaaaaag gtagtagtta
    33301 aagagagttt aagagaattt aaaaaaataa caggtaaaga gtatcaatat attaatggtt
    33361 acaaaggtaa atttatattg aaaggtgata ttgatgattt aaatcttatc tacaatctag
    33421 gaattggttt tagacgtgct cagggatttg gagatgtaga tattttagaa tggaggtgag
    33481 ataaatgaag ttaagagttt atagaggaga ttggtttttt aatatgggta tagttggatt
    33541 tttaaatata ataaagaaag cagataaaca agctgaaata tttattatgg aagattatat
    33601 cgaatttgat agcttatttc ttgaaaactt tcatgagtat tattttaatt actttatgga
    33661 tgaatatgat gtatcaaaaa gaattaaaaa aaatattgat tacagtataa attttattaa
    33721 atctaagcct gatagaatca aagatggaat taagaaaatt aaagatagtg tgaaacaaca
    33781 aaatgataag attaaaaaat ttgatgaaga aaaatttaac atgataaaag agaagctaga
    33841 tagtatgtct aagataaaaa gttatgatga atttgatagt ttagaagctt tagtagatga
    33901 gactatagat atatttaaaa taaaatcaat aaatgacagg cttacagcaa atctttataa
    33961 atatgtagtt caagataatt attttggaca agttagtttt tttaatgttg ctaaggcgaa
    34021 attagattta gatggattaa aacaggtaat gtttaatgat tatttaagac aaattatata
    34081 ttttggagag ttagaagatt tattagaaga gaatgactat gacaagttga aaaactattt
    34141 aaatgataga ttaaatagta tagctaagga tataaatgaa aaaaaagtta gtaagtctag
    34201 tataaatact atagaaaaaa ttatgaagga aataaataaa aactttataa agaaaaataa
    34261 aagcatagaa gatataaaaa agtatatgga tagtttagaa gtatgtgaaa tgtgtggttt
    34321 atataaggga atattagatg aatactcaga aagtaatttt gctccacttg gagtaagcac
    34381 caataatgct aggaatatgt tttggaatca ggcgtatgta ccatcaatat gtgatatttg
    34441 taagctaata ttgttctgta ctccagcagg ggctacttat acaagaaaga attatttaat
    34501 taatgaagaa aatgagtttt atttatttgt taacatggat acttgtataa atgagctttt
    34561 tgaaagaaat aatagtttaa aagctcaaaa aagtgagtat tcagattcca aagatgaaaa
    34621 tccttttaat cagcttataa aaagtatagt agaagaaaat acattaaaaa gtgaatggca
    34681 acttcgtaat atactttttg tggaatttaa agcaagtata gattctaaaa aatgtaaaat
    34741 aaattatttt aatattccaa cttatttagc aaagtttttt gtaaaagaaa ataaaaaaat
    34801 acaaagtata tatgattata aacttaaatc aaatgtgtta gatttaattt taaaaagtaa
    34861 agacttaaaa catttaatta ataacacttt aaggaatata gttaagagta atttagaaag
    34921 caataataaa tcaaacatat cagggttatc ttgtttcaat gttgttcaat taagaacaat
    34981 attaaataac tataagagag gagtgtataa aatggactat aaaaagttga gaaagattta
    35041 tgagtcaggt tgtgaaatac atgattatta tattgataag aatgctaaaa ataaaataga
    35101 aggaataaca tataaaattt taaatttaat taaggttggt aataaaaatg attttatgca
    35161 aacaatttta agaatttttt caccaagtga aaaaacacca ccagaagaaa ttttacagat
    35221 atttgttgaa gaagatttag attttgaatc tgtagggtat gcatttgtaa caggattaat
    35281 ttctggaaaa tatgaaggaa aagataaact accaaacgaa aaggaggaaa aataagatga
    35341 aaagagggtt aacatttaca gtaatagcac aggctcaaag tttaaactat ggggaaggga
    35401 taggtaatat atcagaatta aaaaaattaa gtagagatga tggaaatata tatacatttg
    35461 catctcgcca gtgtttaaga tatgacatag tacgattagc agcagaattg tttaattgga
    35521 atttacaggt tgtcgataaa gaaaaaggca ctattcaatt taaagacaat ataagtataa
    35581 gagaatcaga agaaatggat ttatttggat atatgaaaac aaataaaaaa gatgagaaag
    35641 ataaaaaagg aggttctttg actagagaag ctactgtaag attaagtaat gcaatttccc
    35701 ttgagccata tagaagtgac atggactttt taaataataa aggattagca gatagaatag
    35761 gagaacatcc taatcttgct aacatagagc aacatttaag ttattataca tatacagtga
    35821 ctatagattt atctaaaata ggtaaggatg gagatataga acttgataat aaagagaaat
    35881 gtagaagagt agtagaattt ttagaaataa taaaagtatt gaatagaaat attagaggta
    35941 gacaagaaaa tttatctcct ctatttgtag taggaggagt atatgaaata gcaaatccat
    36001 ttttcttggg tagaattaaa ttaaaaggag ataaaaatgg atttaaaata aataagcaag
    36061 ctatagaaga agtaattcaa ggtacttttt taggaaaaga tttaaaagaa tttacctatg
    36121 ttggaatggt agatggggta tttataaata aagaagaatt taagggattg tttgaagata
    36181 attttttaag tgtagataaa ttttttggac aactagttaa agaagtaaag gaatattatg
    36241 gggtgaatta atatgaaggt tttgaaatta gatttatttc aagaaactgc atgctacaaa
    36301 aaaccatttg ctatgaagat tacagagaca tatccactgc ctccatattc tacaataaat
    36361 ggattaattc acaaaatatt aaatgctaca gaatatatac catttaatat aagtgtacag
    36421 ggaacatatg aaagtatatt taataattac cagacaacat atttttataa aaaagatagt
    36481 attacatcta tgccaatgaa tagtcatatg ctattgaatg taaatttgat aattcatata
    36541 ggtggggatt ttgatttatt ggaagaaata tatgatagtt tattaaatta tgacgagcac
    36601 ttatcattag gtagaaaaga agatttagta agaattaatg atattagatt tgtagaagtc
    36661 aataaatttg aagtagatga ggatatacaa ttagatgatt atgaaaatta taagttatca
    36721 gaatgtaata taagaatgcc ta
//
LOCUS       DAGQVA010000039        36737 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.039, whole genome shotgun sequence.
ACCESSION   DAGQVA010000039 DAGQVA010000000
VERSION     DAGQVA010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.039"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            234..935
                     /locus_tag="MIV85_002075"
     CDS             234..935
                     /locus_tag="MIV85_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBY2961410.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            1205..2023
                     /gene="larE"
                     /locus_tag="MIV85_002076"
     CDS             1205..2023
                     /gene="larE"
                     /locus_tag="MIV85_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBY2961411.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            2078..3226
                     /locus_tag="MIV85_002077"
     CDS             2078..3226
                     /locus_tag="MIV85_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBY2961412.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            3362..4750
                     /locus_tag="MIV85_002078"
     CDS             3362..4750
                     /locus_tag="MIV85_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBY2961413.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            4779..5477
                     /locus_tag="MIV85_002079"
     CDS             4779..5477
                     /locus_tag="MIV85_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961414.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            5480..6913
                     /locus_tag="MIV85_002080"
     CDS             5480..6913
                     /locus_tag="MIV85_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2961415.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            6935..7672
                     /gene="truA"
                     /locus_tag="MIV85_002081"
     CDS             6935..7672
                     /gene="truA"
                     /locus_tag="MIV85_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBY2961416.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    7783..7990
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8243..9442
                     /locus_tag="MIV85_002082"
     CDS             8243..9442
                     /locus_tag="MIV85_002082"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBY2961417.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            9689..10735
                     /locus_tag="MIV85_002083"
     CDS             9689..10735
                     /locus_tag="MIV85_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBY2961418.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGEYLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNNSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            10843..12006
                     /locus_tag="MIV85_002084"
     CDS             10843..12006
                     /locus_tag="MIV85_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2961419.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(12095..12475)
                     /locus_tag="MIV85_002085"
     CDS             complement(12095..12475)
                     /locus_tag="MIV85_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBY2961420.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(12478..13137)
                     /locus_tag="MIV85_002086"
     CDS             complement(12478..13137)
                     /locus_tag="MIV85_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBY2961421.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(13243..14217)
                     /locus_tag="MIV85_002087"
     CDS             complement(13243..14217)
                     /locus_tag="MIV85_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBY2961422.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(14257..14604)
                     /locus_tag="MIV85_002088"
     CDS             complement(14257..14604)
                     /locus_tag="MIV85_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961423.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(14822..15778)
                     /locus_tag="MIV85_002089"
     CDS             complement(14822..15778)
                     /locus_tag="MIV85_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBY2961424.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            16221..16589
                     /locus_tag="MIV85_002090"
     CDS             16221..16589
                     /locus_tag="MIV85_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBY2961425.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            17014..17259
                     /locus_tag="MIV85_002091"
     CDS             17014..17259
                     /locus_tag="MIV85_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961426.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVINKVKTG"
     gene            17358..17621
                     /locus_tag="MIV85_002092"
     CDS             17358..17621
                     /locus_tag="MIV85_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBY2961427.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(17906..18853)
                     /locus_tag="MIV85_002093"
     CDS             complement(17906..18853)
                     /locus_tag="MIV85_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBY2961428.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(18856..20487)
                     /locus_tag="MIV85_002094"
     CDS             complement(18856..20487)
                     /locus_tag="MIV85_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBY2961429.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            20617..21534
                     /locus_tag="MIV85_002095"
     CDS             20617..21534
                     /locus_tag="MIV85_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2961430.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(21591..22166)
                     /locus_tag="MIV85_002096"
     CDS             complement(21591..22166)
                     /locus_tag="MIV85_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBY2961431.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGDGDDEQINVDLSKIPQNIA
                     KISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAELY
                     RHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(22206..22772)
                     /locus_tag="MIV85_002097"
     CDS             complement(22206..22772)
                     /locus_tag="MIV85_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBY2961432.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            complement(23228..24088)
                     /locus_tag="MIV85_002098"
     CDS             complement(23228..24088)
                     /locus_tag="MIV85_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBY2961433.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            24237..25127
                     /locus_tag="MIV85_002099"
     CDS             24237..25127
                     /locus_tag="MIV85_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2961434.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAA"
     gene            25345..27099
                     /locus_tag="MIV85_002100"
     CDS             25345..27099
                     /locus_tag="MIV85_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBY2961435.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKDTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            27483..28469
                     /locus_tag="MIV85_002101"
     CDS             27483..28469
                     /locus_tag="MIV85_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBY2961436.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKKLKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     EMSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            28638..28786
                     /locus_tag="MIV85_002102"
                     /pseudo
     CDS             28638..28786
                     /locus_tag="MIV85_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            28805..30286
                     /locus_tag="MIV85_002103"
     CDS             28805..30286
                     /locus_tag="MIV85_002103"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBY2961437.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            30312..31283
                     /locus_tag="MIV85_002104"
     CDS             30312..31283
                     /locus_tag="MIV85_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBY2961438.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(31539..32141)
                     /locus_tag="MIV85_002105"
     CDS             complement(31539..32141)
                     /locus_tag="MIV85_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2961439.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKSVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILSNSIELDNC"
     gene            32422..33633
                     /locus_tag="MIV85_002106"
     CDS             32422..33633
                     /locus_tag="MIV85_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBY2961440.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            33701..33898
                     /locus_tag="MIV85_002107"
     CDS             33701..33898
                     /locus_tag="MIV85_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBY2961441.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            33932..34903
                     /locus_tag="MIV85_002108"
     CDS             33932..34903
                     /locus_tag="MIV85_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2961442.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFRNALWMYKFTGLFIKDKTK"
     gene            35090..35467
                     /locus_tag="MIV85_002109"
     CDS             35090..35467
                     /locus_tag="MIV85_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2961443.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            35998..36657
                     /locus_tag="MIV85_002110"
     CDS             35998..36657
                     /locus_tag="MIV85_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBY2961444.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
BASE COUNT        14314 a         4155 c         5688 g        12580 t
ORIGIN      
        1 attattaacc atgaacattt gttttgtgct atcatattta tataagggaa ttgtcataaa
       61 aaatatcttg ttcatacagt tttatataga aaaaagaaat gaatcttttc tttatataag
      121 tatattttgt aaattgcctc tatatttata gtttaaataa tagtggtatt aaaaatctga
      181 caacaaaaat aaaactttca aaaaattaaa tctaaaaaga ataggagata aatatgagta
      241 ttgaagattt atatgatttt gaatgtgttc ctttgaacaa tgagattgat attgatgttt
      301 tatttgaaaa gatgatagaa gatggaaaag aaaaagaata tacaccaatt atagtcattg
      361 atgaaaaagt agggctatta agaaaaaata tagatatgat tactaaagag tatggttctc
      421 ttgaaaacta tagagagtat tgtttaacaa aatataatga aattgatgta aatcaatttt
      481 ttgattttag gaagagtgag atttcagaat tattaaagga gctaattgat ttagaagatg
      541 atttttatga ttataaacat tttagaccca ttatgaatat agatatattt catgaatata
      601 acaaagttta catagctaaa attccaacaa ttaaaccata tgaagtattt gcatacatac
      661 ctattggcgg atttaatgat tgtcctagag atgaagaaca tatagctatt gcaaaatatt
      721 ggtatgaaaa gcatggaatc tttccaatcg caattggatg tgatacagtt caatattctg
      781 taaaaaattt aactaaagat ggtaaaaaat ttgatgactt atgtattgaa ttagtatttt
      841 attgtgagga tattattata caagggtatg aaaccttaaa ggctcttaag gatgtattaa
      901 aacgctctac aatagtgctt ttttggtggg attgatattc tatcatttag atagtattaa
      961 attgttagtc accaagaatc cacttgcttt agttataggg agtgtgtcaa actaggtttt
     1021 tatacacagt gtagcatagt aatatgttta aattacaaag gttaaaaaaa tactttaata
     1081 tttttaatat tataattaat agatttaagg taattataat ttataaaata aatactttat
     1141 atgttataat cattaagaat gtaaaaaaat aatatatagt tttatagttc atatttttcc
     1201 agatatggag gtaaattttg tgaaggaaaa agaaaaatta gataaattaa aaaaaatgtt
     1261 acttgaatta ggcagtgttg tagttgctta ttctggtgga gtagatagta attttttgct
     1321 taaggtcgca aaagatacat taggtgaaaa tgttatagct gtgactattc atgcaatgat
     1381 gcattcaagt agggaaattg aagaggctaa acaatatact caaaattttg gtgttaaaca
     1441 tatcatatta aatatagaaa actttgattt aaaagaattt aaagaaaatg gtgttgatag
     1501 atgttatcat tgtaaaaaat atatattctc taaaataaaa gaggtagcaa aagaacataa
     1561 tataaagtac atagtagatg gaacaaatat agatgattta ggagactata gacctgggct
     1621 taaggcattg agtgaattag gagtaattag tccattaaaa gatagtagtt taaaaaaaga
     1681 agaaattagg tcgctttcaa aaacattagg attaaatact tttaataaac catcatttgc
     1741 atgtcttgcg agtaggatac cttatggagt tgaaataaca gatgaaaatt taagaatagt
     1801 agaaaagagt gaagaatatc tatccaattt aggtttttct caatttagag tgagaatgca
     1861 tggagatata gctagaatag aagttggaca ggaagagcta ggtaaatttt ttgaaaataa
     1921 caattttaat aaagttgata ctaaattaaa aatatttggc tttaaatatg ttacactaga
     1981 tatgtcagga tataaaatgg gaagcatgaa tttaaatgtg tagattattt taaaaataaa
     2041 taagttttat agttaatata aggaaacagg aggttttatg aaaaattata cgttaatatc
     2101 gccatgtttt tttggaatgg aaaaaatgct ggctagagag attactaatt taggatatga
     2161 aataataaaa acagaagatg gaagaataac atataaaact gatgagtttg gaatagcaaa
     2221 gtcaaacatg tggttgagat gtgctgaaag agtacatctt aaaattgctg aatttgaggc
     2281 aaaaagcttt gatgaattat ttgaaaatac aaaaagaata aactggtcta gatatatacc
     2341 ttatggagct caatttccta tatcaaaagc ttcctctata aaatcaaaat tatacagtac
     2401 accagatgta caagccatag taaaaaaggc tatagtagaa agcttaaaga aaagttattt
     2461 ggaggatggt ttgcttaaag aagataagga gaaataccct atttttgtat ttatacacaa
     2521 agataaagta accatttcta tagatacaac aggagatgct ttgcataaga gaggatatag
     2581 agaaaaggca aataaagctc caataagaga gactttagct gctgggctta tttatttaac
     2641 tccctggaaa gcaggtagag ttttagtaga ccctatgtgt ggttctggta ctatattgat
     2701 tgaagctgct atgattggta taaatatggc acctggctta aatagagagt ttatatcaga
     2761 aaagtggaga actcttgata agaaaatatg gtgggatgta agaaaagatg cttttaataa
     2821 gatagataat gaatctaaat ttaagattta tggatatgat atagatgaag aatctataga
     2881 tatagctaga gaaaatgctg aaatagcagg tgtagatgaa tatatagagt ttaatgtagg
     2941 agatgcaact caatttaaaa gtgaagatga gtttggattt ataatcacta atcctcctta
     3001 cggagaaaga ttagaagata aagacagtgt taaacagttg tataaggagc ttggttatgc
     3061 atttagaaaa ttaaaaaatt ggtcgtatta tttgataact tcttatgaag actttgaata
     3121 tgagtttggg caaaaagcag ataaaaaaag aaaattgtat aatggtatgt taaaaactaa
     3181 ctttttccaa tatccgggtc ctaagcctcc tagaaataat aaataagttt tacatgattt
     3241 atttgtaaaa tataaaattt tattaaaata agtaaaacat tatgatgccc tgaaacgtct
     3301 aattattgtg aggagatttt tgtgaacaaa tttaaagatt tataggatta ggaggagtta
     3361 aatgaaagtg ttaaagctta ttactgtagt agccctgatg atgttatttg ttactggatg
     3421 taatataaaa actgaatctc cagaacaatt agcgaagata cctgactatg atgatacaaa
     3481 aaaagtattg tatgatggta ttgaccagtt actaaaacca gattcatcta tgatattgcc
     3541 ttctaataca aaagaagtag gaaaaataaa taaggtagat ttaaacagcg atggaattga
     3601 tgaattagta gtatttgaac aaaaagaaga tttaagtaat aatgtgagtc aggtagggtt
     3661 tgtaaccttg agttacaatg gagaaaaata cgtacttgga gaccattttt tagaaaatgg
     3721 cgaatcaata gaatatgcta atttttatga tttggactca gatggatata aggaagttat
     3781 cttattggtt aaatccaaag acaaaacgaa tatgcatata tataaagtag tagataatga
     3841 aataacaaaa atatatgact tggatgcatc atggcttcaa aataaagaag attttaatga
     3901 catgaaagta aaaattggat atatagatgg agatgacaag ttagacatat tgatgcttca
     3961 tttgaataat aagactaatg aaatgtttgc aagtgttgca aattttgatg ggaaaatgaa
     4021 aatcaaagat tctgttaagt ttgaaaatgt aaaaaactta agtgaattat atataacatt
     4081 aggtaatgtt gcttcatctg ttggaaattc ttctgcagct ataaaaggta ttgtacttga
     4141 tattcctata ttgaaagata ataactatat tacgcagata ctttatatga aagatgggaa
     4201 aattaacaaa gcttttagtg attatgataa aactattact aaatcttatt atatacctgt
     4261 agatgatatt gacaaagata agattataga aatacctata gttgcaggca gtacaggtaa
     4321 taataaaaat acttatagtt ctaaatcatc tgcaactata agttggtata gatggaatgg
     4381 aaaagaaggt gctgactcaa gtttaatatt tacaagtcag atatattata attataaata
     4441 taattttaaa ttatttattc caaataattt atttgataaa atacttgttg aacaggaatt
     4501 tgttggagaa aaagcagtat ttaaatttta ctattttgac tattcagacc gtaagaattt
     4561 atttaatata gtagtagaga gtaaaaataa acttgaagat agaaaaaata caggtactca
     4621 aaattctatt gtacttcaag agagcgatga atatactttc ttactagttg taaacaatgc
     4681 aaatgaaatg gataagctag atatgactat agacgcatta aaagaatatt tctcattaat
     4741 atatggttaa tattatactc aattggaggt tttattttat gaaggaaaag atacttatac
     4801 tagaagatga aattggtatt agaagttttg ttagtataaa cttaaaaagg gaaggctatg
     4861 aaatagttga ggcaggtact ggaagagaag ctatagaaaa aatgacaaca gaaaaggata
     4921 ttacaatagc tcttttagat gtaatgcttc cagatataag tggtatagaa gtatgtaaat
     4981 ttataaggga gaattttgac caagtaggta taataatgct tactgctaaa gctcaagaag
     5041 atgataaaat agaaggattt atctcaggag cagatgatta catcataaaa ccatttagta
     5101 taaaagagct tttagtcaga gtttctgctc ttcttagaag agtagcaaag gatgattcaa
     5161 gtgttaagtc gagtgagata gtttctccac catttatact tgatatagac aaaagaaaat
     5221 tatttaaaaa tggaaaggaa attgagctta caccaactga attttcaata gtgaaatatc
     5281 taatatcaaa tgctaagcag tcgttaagta gagaccagat attagacgaa gtatggggaa
     5341 ctaactattt atatgatttt aaaatagtag atgtaaatat aagaaggata agaaataaaa
     5401 tagaagatga cccatcaaaa ccaaaatata tacaaactat ttggggttat ggatactgtt
     5461 ttagaaagga agaataatag tgttacattt tgaaggtctg agaaaaaaag taataaaaaa
     5521 ctattttata ataattatta taatggttac tctgtttgaa ggattgttca tgttttacat
     5581 acaaaactac tattatgatt ctgtcaaaca gctacttgaa tctgaaataa aatatgctga
     5641 tgaatataat gctattacaa tggaaactac aagttttgag aaaaaagtaa aaaatatatt
     5701 tgataaacaa cccttaacta aaaattcaga atttggaatt tcaataatag ataaagataa
     5761 aaatattata ttagaccaat atggttttaa aagtaaagaa aaagcaaact atgaagatgt
     5821 taacaatgca ttaaaagata taaaaactaa aaatttaaca ccttatactt atagaatacc
     5881 agatacaggg gagcatgtta tgagtatctc cttaccactt aaggtaaata atataataga
     5941 aggtgttgtt agatatacag tatcattaga tgctattgat aatgcaatat taaagcaagc
     6001 tacatggctt atattagcag gaatatttat acttattata gctatactaa taagtcttaa
     6061 atttgctgag actcttataa aaccattacg agagctaaag aaatttgcaa atgaattggc
     6121 tgtaggaaat tataatataa aattagaaaa gatgaagatt gtagatgatg aaattggtga
     6181 tttagcacag acatttgaac acatggcaca tgagattgac aaaagtgaaa aattaaaaga
     6241 ggaatttata tcatctgtat ctcatgaact aaggactcct cttacatcta taaaggggtg
     6301 gagtgaaacc ttaggttatg aaagtataac aagagaagaa ctagacttag gtttaggcat
     6361 tatacaagat gaaacagaaa gacttataaa actagttgaa gaattattag acttttcaag
     6421 gctttcttca gacaggataa aacttcatgt tgatatagtt gatgttgaag gtttaattgt
     6481 aggtgttgta aatcaactta aagttaaagc agctgaaaaa gatatatcac ttttatttga
     6541 atttgaaaat gaatttatag agaacattca aggagataaa aatagattaa gacaggttct
     6601 cataaattta atacaaaatt catttaaatt tacgagtcaa ggtggttaca taaaagttgt
     6661 agcttctcaa gatgaagaga taacaaccat atcagtagag gataatggtt caggtataga
     6721 aaagcaaaat ttaaataaag tgttagataa atttttccaa gaagattata ataaggctgg
     6781 tagtggatta ggactagcaa ttagtaatga aattgtaaaa cttcatggtg gaagaatgaa
     6841 aatagaaagt gaaaagaatg ttggaacaaa aataactttt aatataaaaa ataaatttgc
     6901 taaacaagca taaattctta gaaagaggat taagatgaga aacataaaaa tgatagtagc
     6961 atacgatggt tcaagatata aaggatatca aaaattaggt gacaataata tgactattca
     7021 agaaaaactt gaaaatgttt taagtaaaat gactaatgaa acagtggaga taataggttc
     7081 tggaagaact gatatgggag ctcatgcaag aggacaagtg gtaaatttta gaactaattg
     7141 tatggattct ttggataaaa ttcaaaaata tttatatgaa tatttaccag aagatatagt
     7201 tgtaaaaact gttgaagaag ttgatgaaag atttcattca agatacaatg taaaatcaaa
     7261 gacttatatg tataaaattg acaataataa gtatcataat ccttttataa gaaaatatgc
     7321 tactcatgta agtaaaaaat tagatttaga tagaatgaga aaagcaagtg agtatttagt
     7381 aggagaacat gattttacta gttttgcttc ttctaaatct aagaaaaaat caaatgtaag
     7441 agaaatttat tctataaata taaaagaaga tgataatgtt atagaaatat atgtagaagg
     7501 aaatggattt ttgtataaca tggtaaggat aatagtaggt gctttgatag atgttggtct
     7561 aaaaagaaga gctccacaag atattaagta tatgcttgaa tcaaaagata gatgtcaatc
     7621 atcagatact gcaccagcta aaggactatg tctttggaaa gtaacatatt aatcaattat
     7681 ataaaactct ctttaaaata aaaataaaat aaattatata gttgacataa atggaaaaat
     7741 aaactattat atattttata agagagatat aaaactttat atttaaatcc tgtgagaaag
     7801 agagtaactt ctatgtgttt tatagagagc tgaggatggt ggaagcttgg caaataagta
     7861 ttagtgaaaa gaactttgga ggatactaat tgaatttagt atgttagtag gtaatctcgc
     7921 cttaagagaa agagtggata agtttatctt atcaattaga gtggtaacgc ggatatattt
     7981 cgtctcttgg tttttccaag aggcgttttt taatatattt aattattagt gtttatctgg
     8041 tatgttgaac atttactaat tgattagcta agtttatcaa taagagtggt accgcggata
     8101 tttcgcctct tagtatttta aaatactaag gggttttttt agtattaaaa tgattttatg
     8161 tgagtctaaa ttctcagagt cattcaatat taagaatttc tataaaataa aaattataat
     8221 ttaagattgg gaggaattaa aaatgaagga aaaagtagta ttagcatatt caggaggact
     8281 tgacacatca atcataatac cttggttaaa ggaaaattat gaagatatag atgttatagc
     8341 tgtttgtgga aatgtaggtc aggaagataa aatggaagat gtatatgaaa aagctttaca
     8401 aagtggagca tcaaaggcat atgtggatga tataagtgaa gaatttgtaa ctgaaactat
     8461 atttaaagct gtaaaagcag aggctaaata tgaaggaaaa tacttattag gaacttcttt
     8521 agcaagacct ataatagcta aaaaattagt tgaagttgct cataaagaag gtgcaaaata
     8581 tatatgccat ggatgtacag gaaaaggtaa tgaccaagtt agatttgaag ctacaattgc
     8641 agctcttgac ccaactataa aagttattgc accttggaga atttgggata taaaatcaag
     8701 agaagatgct atagactatg ctgaaaaaca taatataaag gtaacagcaa ctaaagctaa
     8761 aatatattca gtagatgcca acctttggca tgtttcaaca gaaggtggag atatagagca
     8821 cctagaaaat gaacataaaa aagatgttta taaacaatgt gtagacccag aagatgcatg
     8881 tgatgtagct gaatatgtag aagtttactt tgaaaaaggt gtacctaaaa aggtaaatgg
     8941 cgaagaatta tctccagttg cactgattca taagttaaat gagttgggtt gtaaacatgg
     9001 aattggtgtt atagatatag ttgagaatag acttgttggt atgaaatcaa gaggtatata
     9061 tgagactcca ggaggaacaa tcctttatga agcacataat attttagaaa gtgctacttt
     9121 agacaaagat acattacatt tcaaacaaat ggtatcttat aaatacggag aacttattta
     9181 caatggacta tggtattgta aattaagaga atctatagat gcatttatgg aacaaactca
     9241 agataatgtt acaggaacag taaaagttaa actttacaaa ggaaatataa aacctgctgg
     9301 aatatttact gaaaatgctc tttatgatga aggaatatct tcttttggaa atagtgaact
     9361 ttatgaccac aaagatgcag aaggatttat taatttattc actttaccat taaaaatcag
     9421 agctatgaaa gctggaaaat aataaaataa attatttaag agtgtataaa aacgattttt
     9481 aggtttttat atgctctttt tttatttgaa tttattaaat tatacagtaa atagtataaa
     9541 aaaatatatt atagttccaa atggcttaat aatgtgaaaa tataagacct aaaatataaa
     9601 ttttataaat acaatagtta ttgactctct cattgtaaga gggtttatac tgaatctaat
     9661 gaaaatttat agtgaggaga tagattatat gagaaaaata attgaaatta aacatcattc
     9721 acatgattat gagtgtatgt ggaatggtat agaagattta tatataaata aaaccggtga
     9781 ataccttcca aacgattttt tctttttact gtcaggtttt ggttcatttt gttatatgaa
     9841 aacaaataaa gctgatttga aaagaatggt agctttggga gatggaagga caaaacagat
     9901 gtataaattt ttagcaccaa ttgttggatt tgaatacaaa catcatgagt ttaaaaagta
     9961 tgagcaagca ttaaagaaag caaaatctga aattgatgat ggatatccag ttattttagg
    10021 agctttagat atgtattatc taccatatta taagaagcta tatcataaag aacatattcc
    10081 ttttcattat atattaatgg taggatatga tgatgaagga atatatctgt atgattgtgg
    10141 tagaacagaa ttattacatc tttcttatga taaattacgt gaaagcatga attgcaattc
    10201 ccctggatta agcaaagaaa atactatttg cacaataaga atgaatactt caaagaataa
    10261 atataacatt gctagagaag ctattgctat aaagcgtgat atgtttttaa atccacctaa
    10321 aggatttttg ggatataaag gttttgaaaa gtttattaaa gagttgccac agtggaacac
    10381 tgaattggat aaggatgatt atgataagat tttgaccaat atggttatgt tttttggaac
    10441 agtaccaaca attccaaatg caatcaaagg aattaaagaa ccagatactg ttcaatttaa
    10501 aggtggattt gataaaatga gtagaatgct caacagtatt ggggaggaat acaaaaacaa
    10561 ctcttttata caagtagctg atatttttga taaaactgct attataattg agaaaatatc
    10621 caatattata atagattact taactcaaac atgtgatgat acagaacaac ttccgttatt
    10681 gttctctgag gtcttagagc atatgaaaac aggatattta atcttggatg tataaaaaat
    10741 atattgttga ccctaacatt acgtaatagt gtaatatgaa aatatagctt aaatatatta
    10801 gtaggtattg atggctgtaa aattaaaatt tgaggtgtgg atatgagaac agtgaaacaa
    10861 gtttctgatt taactggaat aagtgtgagg gcattacatt attatgatga aataggtctt
    10921 ttaaaaccaa ataaaattac agatgcagga tatagacttt atgatgatga atctattaaa
    10981 actcttcaac aaattttatt ttttaaggag attgatattc ctttaagaga ggttaaggaa
    11041 ataatgtcaa gccaatattt tgataaggtt gaagctctaa aaaatcaaaa aaaattactt
    11101 attttaaaac gaaagagact ggatgaattg atagagctta taaatcaaac tctaagagga
    11161 gaaggaaata ttgattttaa agagtttgat atgagcgagt attttaatgt tttagaagaa
    11221 tttaaaagag agcataggaa taaggtaatt aaaatttatg gtagtgtaga aaaatacaat
    11281 gaatatatag aaagagttaa gtctaatgaa gagaaaattg ctaaaatggc tataaaacaa
    11341 tatggaacta ttgagaagtt tgctaaagct ataaaaacaa attttagcag tgatatattg
    11401 aatttaggag aaaaatttga tagatataaa aatgattgtt taaaagaaaa acatccaaaa
    11461 ttaaaagaat tatatagaaa gcttgtagaa gatttaagta ggaatccttc ttcaacagac
    11521 cttcaagaaa tagcaaaagc gataacagat atatctaaaa aagattatga aattttctct
    11581 atggatactg gtgatgacaa ctggtattat atggttcaaa attatctagt aaatcctatg
    11641 tggatagaag aagtagataa aaagtatgga agtggagcag gaaagtttat tggacaagta
    11701 ctaaagactt atctaagaga tagaaaacca aagataaata cattgtatga aaaacttgta
    11761 gaagatttga gtagagattg ttcttcaagg gaagttcaaa gcattgttga agaaatagac
    11821 aatgaaatga aaagaagtaa tgaattttat aaaatagaca atggtgaaag atactttgat
    11881 tatatgtcag agctttattt acaagattct aactatataa aagtaactga taagaattat
    11941 ggtgatggtg catctaagtt tattggagaa gcttttaaga tttattttga taataataat
    12001 tgttgaaaat ttggaagtaa aaaatatgta agttttataa aagcacaaaa ataaggatgt
    12061 agattagctc catctatatc cttatttaaa gttattaaaa tatatagttt acatcaaact
    12121 taacactttc aataatattt cccaaatatg tttttatact ttcaacttct tctaaagatt
    12181 ttaatttatt ttcagtataa attgctttgt ccagaatatt aaaccttaat cctatttcat
    12241 caaagtactc atgatttaaa actttgtacc aatggttttt ttctttattc caactcgtag
    12301 atattgaatc agcttctttt tgagcttttt cccaatcttc attttctata gatttttcta
    12361 aaacagatat attgtcttta tatccttctg taaaatcata tagtttattg ttaacgtaaa
    12421 atccaaataa tacaaataag atagtccata gtataacaaa tgttgtagat ttcaatatta
    12481 atcacccttt ttattttgaa taaatatttt gtcattttca tctaaaacac aaataagaac
    12541 atctttaaaa gtttctatgt gattagattt taaaataccc attaaccagt tagtatcttt
    12601 ttgagctatg tctagatttt tatttattat tctaccatcc agtataagtg ggataggtaa
    12661 atgattaaaa gctcttggag gagtactatt gtagcttgat gctggtacaa cacttagatt
    12721 accatcagtc tccaaaatag catattgtac atcttttagg ttaaagtatc cttgaatcct
    12781 aagttgttct aataattcat ctatactaat tctttctttt ttaagctctt tatatacaat
    12841 ttttccttta tctattaata cagaaggttt acctgataaa aatgaactta attttctgct
    12901 ttttaatgat aagaatgaaa ttagagtctg catgattaca agtccagata ttgctgcaac
    12961 accatttatg attggtatat tattattttc cattgggaca gatgcaactt ctgcaattaa
    13021 tagtgttata actaaatcaa aacagttcat ttcagctatt tcaccttttc ccatgactct
    13081 aagtgcaatt agcactgtta tgtataatat aatacttctt attaatacta ctgtcatatc
    13141 tatcaattac tcctttaaaa aatatttaca cttagttagt atatcctata taaaaaattt
    13201 aattcaaagt ataaaaaacc ttaaataatt ggattcaact atttaaggtt tttttgataa
    13261 ttttaatatt aaatttttta tggattttct gttactttta tttattttaa taacagattc
    13321 aacaaaactc tttttatctc ctaattttaa gataaaatca ggatattctt caaattcatt
    13381 gagttttatt aatttgaaag aagaagatag atttttaaag ttaataattt tagagttatt
    13441 cactaataca cttctttttt taaaataaat ttctttttta cttatattta gtatagttaa
    13501 tatttgttta agatatatta ttatatcttc tggagttcta tcaaatttga gttcaaaatt
    13561 ttcatcttca aagtagggaa tataatataa aggtgttttg agagcaggta atttattata
    13621 taattcttca agaatatcga tatttttagg ggagttaaag aaaaagcatt tacatacatt
    13681 cattaaatcc acagcatctg aaagtgagtt atgtttaata tctccttcta cagaaaaaat
    13741 ttttttcata ttcagtaaag atatttgctt agataagatt ctattattgt atgtaatatg
    13801 ttgagatata aaaggttgaa tgtcaatcat catattaaat aactctaagc atttacctgt
    13861 atatttatac actctaaatg aagttagaag gccagttata tcaaaatcac cccaattata
    13921 tattgtaaca tcatcaaatt tacaaaacca tttataaaaa tcatccataa catataaaag
    13981 attaggagca ttattgatat ctagttggtt caatttggtt aaatttttac atttatttga
    14041 aagtatttta ttgtattttg gcttaactaa agagtaataa ttatctattg tattaaattc
    14101 gttatcaact aaaactccac caatagaaat taattccgca ccattatatt cttttggttt
    14161 atttttatta tcatctagta tattaaattc aaagtctata aataacttgt atttcataaa
    14221 tctaaagcac atcctcaggt aaattattta ttgagcctaa gcatcataag aatcaataga
    14281 tataatgact ctaaacatca aaggttcatt acaactttta tttatttcat aatttaattc
    14341 aaataaatct tttaagatat aatttataag tattctttcc caacccattt ttaaattaac
    14401 tttagagtct attaatatat tttctatctt tttaaatatt tctatatttg ctggtattat
    14461 actgagctca atattacttt taaacgggtt agactgtaaa tctgttataa gtatattttt
    14521 taattcctct gtaagttcag aaattaaact atcacctatg tattttttta tgatttcctc
    14581 tctaatttct tttaaattta gcaatattag tacctgctac ttacatagta gcttttcctt
    14641 tccttttaat actattattc atttttgaat cttatttaga tatattttaa gattaaaagt
    14701 ctttagctat ataatttttt acccattttt aacttatatt aacatattac aggcttatat
    14761 ctccaccctg tttacattga ggatggagta tattgcctat tttgataaaa atgataggtt
    14821 gctatttgcc tattcctttt tctgataatt tttctaacat atctttggtc attttatcta
    14881 aatcataact aaacttaaag ttccattctt ttactgcact actactgtct agagagttag
    14941 gccaagaatc agctatactt tgtcttacag ggtctacatc atattctatc acaaaatcag
    15001 gaatatattt ttttatagaa tcagctattt cttcaggaga aaagctcata gcagtaatat
    15061 taaaagcatt tctatggatg agtttatcag ctggagcttc gattaaatcc actattgatt
    15121 gaagtgcatc aggcatatac atcatatcca tttttgtacc ttctgctatg taagatttat
    15181 atctcttatt ttttaatgcc tcataatata tatcaactgc ataatctgta gttcctccac
    15241 caggaggcgt aacataagaa ataagacctg gaaatctaac acctctagtg tctactccaa
    15301 attttgagtg ataataatca catagtaatt ctccagaaac tttagtcaca ccatacatag
    15361 tattaggtct ttgtaatgta tcttgaggag tcatattttt tggagaattt tcaccaaaag
    15421 cagcaattga actaggtgta aaaaatttac aatccaattc tttggctatt tcaagaccat
    15481 ttattaatcc attcatattt aagttccaag cttctagagg tttactttca gcaactgcag
    15541 aaagtaaaga tgctagatga attatagtat ctacatcata tttttttgca atttcaaaaa
    15601 aacgattctt atctgtaaca tctaatatct caaatatacc agattcacat actggattac
    15661 cttcttttac tctccttgaa ctagcgatta cattttgttc tccatactca tttctaagct
    15721 ttattgttaa ttctgaacct atttgtccta atgcacctgt tataagtatt tttttcaatt
    15781 ttacaacctc ctaagggttt aatttatgta gtactactta tttttatttt agcaaatctt
    15841 ttgtttaaat acaaagaatt aaagataata atatacgact taattgaatg aagtgcagta
    15901 agtgcgtaaa aatttaaagc taatatataa tggtctattg tataacaata aaagagtaga
    15961 ttaaattatt atatatagat tgtgtgacta agtcacagaa aatagagcta atttaatata
    16021 taataaaagc atgtcaagta aagctttaaa ttaaagtaac tttatataaa aagtaatata
    16081 aattgataaa attataaatt tatttatagt gaatataggt tggattttat agatacaaaa
    16141 atagtatata tgatatgtag accattagca tgtttaaagt agcaaaacat ataaaataaa
    16201 atttgaaagg aagtataaaa atgacaagac catcaatata tcatagccaa ggatacactt
    16261 gtgcagaggc attaataaag tcttataatg aggaacacaa cacagatata ccaatctcaa
    16321 taggaagtgg tatgggggtt ggaatgaatg ttggaagtgt ttgtggagct gtaaatgctg
    16381 ctgttgttat aatagggtat ttaaatgggc gaaatagtaa tttagatgaa aatatagcaa
    16441 ggaagtattc aagagagcta ttgaatagag taagaaataa atacagctca gaaatatgtg
    16501 tatctcttaa aaaaaataaa gtaacttgtg aagaaataat aaatttcaca tatgatgctc
    16561 taaatgatat gctaaaaaat caaaaataat tctaagaaac aagtatttta cattcgatag
    16621 aatacttgtt tttttatgat atttttaata agtattagtt tattataatt tttaaatcaa
    16681 ttttattata ttttaattga aataatctac tttgaaaatt actaactgac aaaagaatat
    16741 gattatagta tagaaaaaat gtaaattatt taatattaag tgagagtata tgcttaccta
    16801 tataaaatcg tataaattaa tggctaaatt tataaattat aaagaaatat ataggaaaat
    16861 aaaagaatta attagtataa tataaagtta aaaagtgaaa atttatataa tttatttata
    16921 aagtaaagaa aaaatagaaa tttgtaataa aataaaaagt ttatgacata atatggtata
    16981 attagtaaaa atatagagat tggaggaatt gctttgttta tagatgaaga attagaaggt
    17041 tatatattaa catgtaaaat atctgaagac tttaaaaata tacctgaata tagtgatgaa
    17101 gagttttatg ttacagtcta taaagatgaa agttctgact ctgggtacta tgctttatta
    17161 gaaaataaag aagaaagagt tgtatgggat ggagaagttg ttgccaataa tatttttaat
    17221 aacctttgga ttgtaataaa taaggttaaa actggataat agtctaatta tatagtattt
    17281 gtaatatttt aaatgaattt ttacatattt gagatgagta aataacaaag attattcgat
    17341 actggaggag taattcaatg gaatatagtt atagtaagat gaacttaaaa aaaggggata
    17401 ttgtagaggt aaatttagag aaacaagcca atgtaatatt gttagaccat ataaattatg
    17461 tgaaatttaa aaatcaaaga aattatgatt actatggtgg atttgcaaag aaaaatccat
    17521 gtagaatgag agttcctaat actggaacat ggtatctagt agtaaatcaa gatggaaata
    17581 gtggaatagt aaacttttca atcaatacaa ttcaaaatta attttagaat attggatatt
    17641 cttacttttt gtacttttta tatagttaaa ataaaattaa taagcaatta ttataaaata
    17701 atgtgggtgc ctcaaaatga attttataat tcacgagaca ctctttttta tatgaactca
    17761 aatatacttt atcatttcaa caatgaaaaa gaggcgtatc tgtgttttga gatagcctca
    17821 tttatcatat atcatatata gaattttaat tattcttaac taaaattttt tccataggtt
    17881 atctgtacaa ttaaaatatt tattgttagc atacagctcc acctgtaagg tgtaaaagag
    17941 cctctagtat ctcttctttt ctttccaaaa cttcatctga taaaagcatt tctataaatt
    18001 tatcagcacc gattctatcg atagttattc caaaacgttc acctgtgtta ccctgttctc
    18061 taaataaaag aattgctttt tcaattaaag tcataagttc ctcttttgaa aataatctat
    18121 caatctgtgt tccaggacga actgattttc cccatttccc tcctatatag actttataac
    18181 cagattcttt ttcttcaata ctatcaaaat tacaactttc tatacactta ccacagttat
    18241 tacatagatt actatctatt tcaagtttac ctttatctgt taatttagct gctttaacag
    18301 gacagacctc tacaacagca cattttttac aaccaacaca aagctctgaa tcatagtcag
    18361 gtacacgttg accaacaatt ccaagatcgt ttaggtcagg tttaatacag ttattagggc
    18421 atccaccaac accaattttg aacttatgag gtagttttac atcataccaa tttttgtaaa
    18481 attcttcgtg tatttcagca gcaagtgcct gtgtatcagc tagaccatga acacaaacag
    18541 tacctttaca agccacaaca ggacgaaccc ttgatccagt tccacctgtt attagatttt
    18601 cgctagcaat aaattcactt agagcttcaa tatcttcaaa ttttacacca ggtaattcta
    18661 ctgttagtct agtagtaaat gctaactgac cgtttccgaa tttttcagca gcttctgcaa
    18721 ttttttttgc ttgtgatgca tttattacac catttacagt tattatacgt gctgcaaaat
    18781 gttctccatc cctgcttggt agaaaacctc taccttttac ttcctttttt tgttctgctg
    18841 taacattact catatttact cctccattac cttaagattt ggataaaata gtattccacc
    18901 ttcaagaact ttcgtatttg tatagccaaa gcgtcttaag cgattttgcg ccatatagct
    18961 atttttacct ttagcacata taagaagaat tttttcatcc ttagcaaggc cttcaatttc
    19021 tccattaatt tcaccaacag gaatataacg taaactagga atagaaggag cttttgaaac
    19081 atcaagttta gtccaactgt caaaatcctc aatttcgtca agtaaaacac tatcaagttc
    19141 tccattaagt ttattttgta aaacatttac tgccactaca aaagggtgaa tagctgttga
    19201 aaaaggtggt gcatatgcaa ggtccatact ttctaatgaa taaaggtcag cgcctaaagt
    19261 tattgcagta gcagcgatat ctactatttt atcaaccgct ccaggtccca taacttgaac
    19321 acctaataat tttctagtat ttttttcagc aaccattctt ataataaaat tagatgcacc
    19381 tggataataa tgagctttat catcagtagc tatggttaca gagcaaacat tataaccttc
    19441 tttttcagct atttctttac ttagacctgt ttttcctgca ttgagctcag gtaattttac
    19501 tactgttgtt ccaagaacac cattgtaagt tttagatttt ccagatatat tttgtgcgca
    19561 aattctaccc tcatgatttg cagatgaccc cataggtgac catgtaggtt tatttgttaa
    19621 agaatttttt acaaaagcac agtctccaac tacgtatata tctttgtcat ttgtaagcat
    19681 atattcatct gcaataattg tattattagg ggcaaattct aaacctgtgt cttttagaaa
    19741 acctgtgtta ggacggattc caactgacat aaccactaaa tctgttttaa tagctctatt
    19801 tttagtacga agtttttcaa ctttattttc accttcgata cctacaacct ggtcacctgt
    19861 aaaaatcatt atgcctttat cagccatatg attttcaacg tattcagcaa aatcagtatc
    19921 aaatccaggc ataacatgtt cagccatatc aacaacactt acacgtatac ccattgcaga
    19981 aagattttca gcaatttcaa gaccaatgaa acctccacca ataacaacag ctctcttaat
    20041 accgttttca atagaatctc ttagttttat agcatcattt ggagtacgca taaagaatac
    20101 tccaggtaaa tctattccag gtattggtgg ttttattggg tctgcccctg tagcaattac
    20161 aagtttgtca tagcttagat tttctttttc tcctgttgaa agcgttttca aagttacttg
    20221 ttttgcattt ctatcaatag atgtaacttc aactccacaa cgaacttctg ctcctgttag
    20281 tttagaaaaa ctttcaggtg tatttacgat taaagatgat ttatcttcaa ttatcttacc
    20341 aacgtaatat ggaagaccac aacctgcata agaaatatca tcacctttat ttagtattgt
    20401 aacagagcaa ttatcaccca tttcacgttt tatttttgca gcagtttttg ttccagcagc
    20461 aactccacct ataattaata ctttcacaat atatcacact ccaatctact ttataactct
    20521 ataataaaat tatacttctt gacaatatat ttgtaaaata ctaaaatatt aataaaatca
    20581 taagcattta ctaatgtttg ctaaggttgt gataatatga caattcgtag tcttgaaatc
    20641 tttgttaagg ttgctgaatg tggtaaaatg agtgaagtag caagaaatat gtatattacc
    20701 cagtcatcag ttagccaagc tatttcagaa atagaaaaag agtatggtgt taagctattt
    20761 gatagaattt caaaaaaatt atatttaact gaggcaggga aaaaacttct tggatatggg
    20821 aggcatcttt tagctgtaaa tgaagaaatg aatgattgta tgaagcattg tgcaaaaaat
    20881 atccgtataa gagttggggc aacagtaact gttggtacat gtgtaataag tccaataatg
    20941 ttagaattat acaaggtaaa tcctcttata gaacctgaag tatttgtaga agatacaaga
    21001 ctgattgcaa aaaaattact taatagtgaa ttagatattg cgattgtaga aggaaaaatt
    21061 aagcacccag atattgttac aaaaagcatt attaatgata atcttgtact tatatgttca
    21121 cacaagcatg agttttataa aagagactct ataaaagttt cagaactttc aaatcaacca
    21181 ttaattatgc gtgaattagg aagtggtaca agagcacaat tagaaaagca attaaaagaa
    21241 ttaaaaatcc caatgaatat tagatggtca tgttataact ctgaagctat attaagagca
    21301 gttgtagata attttggcat tgcagttata tccgaattac ttattgagga ttatttaaaa
    21361 aagcatcttt tgtgggcttg tgatattgaa ggtattaatt tacataggac atttgatatt
    21421 gcatatcata gaagcaagtt ttttacagaa aatatttcag cattttttga tatttcagta
    21481 gaatatggga aaaaacaagc gagaaagaag agtagaagtg taaacagttt ataatatatc
    21541 taaataaaaa taagagtata tcaatatact cttattttta tttagatata ttagcctata
    21601 ttaacgccaa aatttttaca caatcctgca agtccatcct caaatccaga acctaaagca
    21661 ttaaatttcc attctccatt atgtctatat agttctgcca caactattgc tgtttctatg
    21721 ctaaaatctt cacccaattc atatttaata agttcctcat tagtttcttc attatatatt
    21781 cttatatatg aattttcaac ttgtccgaaa ttttgtcttc ttgtaattgc ttcgtttata
    21841 gtaacactaa atgatatttt agcaatattt tgaggtattt tagataagtc tacatttatt
    21901 tgttcatcat caccatcacc tgttctatta tcacccatat attcaacagc tccagaagcg
    21961 tgttttaaat tattatagaa tataaagtct ccatcattcg ttacttttcc atcagttcca
    22021 gttaaaaatg cagaggcatc taaatcgaaa tcaaagccac catcatattt attaatatcc
    22081 catcctagtc ctactattac tttttttaga ccagggttac tttttgttaa acttactttt
    22141 tgtccttttg ctaaagttat acccatttaa accaactcct cattataaat tttttattgt
    22201 aattattact tatatgtatt aattaattca cgaagctctt cattttgacc aattcctaaa
    22261 gcattaaatt tccattcttc atttctacga taaatttctc ctgccaaaac tgttacttta
    22321 ccagaaaagt cttcttgaag attatattta aataattctt gcttggaatt tgaatcaatt
    22381 aatcttataa aagagttgtt catttgacca aaatcctggt ctcttttttt agctttgtat
    22441 atagaaactc caaaaactat tttatgtaca tattcaggta tgtcttctaa attaacaatt
    22501 atttgttcat catcaccttc accttttcca gttaagttat ctccagtgtg tataatagct
    22561 ttagaagggt gtttaagatt tccaaaataa accaagtcac ctctaacatt cattttatct
    22621 tggttagtca atgctattgc aaatgcatct aggtcataat tttttttacc caatttattc
    22681 atatcccatc ctaagcctac tactagattt tttacaggat tattatcttt tactaagcta
    22741 actctttgtc ctttttgtaa actaacactc attttaagtt ctccttttta tatttttagt
    22801 tttattgatg gtatcaagta taagaaccat attagctata ttatatacgt atttaggcta
    22861 agttggctat atttataaat tatttattat ataactacat gaatatttta taatttaaac
    22921 atattgacat tatatgcttt aaattatttt gtagttttat aatatttaaa tttgtatttg
    22981 attgttataa agtaaagtaa gtaataaagt tagactcaat aattctaaaa tttctaagca
    23041 tactatctaa atgagaacgg atttggaaat acttgtataa aacaataatt gatacattta
    23101 atttttatct taaaaacaac aattataata tataaatagc aagtataata tataaatagc
    23161 aagtataata taacatataa aaagttgaat ttgtatatgt taattatact tgctatttat
    23221 ttgttagtta ttctattttt ttaaatccat tacctaaagc ttcatgtata tctgtaatta
    23281 taataaaagc attagggtcg acatttttta ctaatttttt caattcgaca acttctttct
    23341 tttcaactac tactaaaagt acatttttat tttctccagt atatgcacct tctcctttta
    23401 gaatagttgc acctctatct aaatcttcca ttattttttt acttatatct tttgaaaggt
    23461 cagatataat agtgaatgat ttggaataat taaatccttc aataagcaag tcactaactt
    23521 ttactaaaat gtataaagcc acagttgaat aaagtgcaat ttcaacctgt ctatttacta
    23581 tacctgataa aacaactaca acgcagtcta caatacccat taaaacaggt atactaaatg
    23641 taggaaaata tttatttagt aggagtgcca ttaaatcagt tccacctgta gagccattta
    23701 ttctaaaaat aagtccttga ccaactccca ttaaaataga accagatata attgcaagat
    23761 acatatcatt tgttatatct aatgtagcca tatttgcagt aagcttaagt gctatggtaa
    23821 gaaaaattat tcctaaaacc gttttaaaac aatctttttt tgaaagtatt ttgtaagcaa
    23881 atatgaataa tggaacattt aaaagtaaat tgacaatcca aagttctaca ccgaataatg
    23941 aatttaaaac aactccaagt cctgttatac caccagcagc gattgcatgt ggattaaaaa
    24001 ataagttaag agaaatggcc attaatatac agcctacaat taatattaaa atttctgaaa
    24061 aagttattct atcttttttc aataacatca ctccttatat atagattata atatatatta
    24121 tatagttttt ccaattttta ataaaagaaa taaaaatata ttataaaaac aatttgattg
    24181 gaattttcag aaaattaatg ctataattaa aagtaaattt aaagggaggt tataaaatgg
    24241 ctaaattaac tctagaacat ataaaaggaa atacatatta tattccactc cctacaatag
    24301 taggtgtata cgtagatggt aaggatgcaa ttttaattga cagtggaaat aataaggata
    24361 cagctagaca agttttaaga ttattagaag aacataattt aaatcctaaa ttaataataa
    24421 acactcattc aaatgcagac catataggag gaaatgcata tttgaagaat caaacaaaat
    24481 gcaagattgc tacgactaaa attgaaggat attttacaga aaatccaata ttagaatcag
    24541 catttttata tggtggctat ccaagtaaag cactgaagaa taaattttta ttagcaaagg
    24601 aaagtgaagt tgattatatt ataccttcaa atggcaaaat tgtagataca gaacttgaag
    24661 cgatttctct tccaggtcat tattttgaaa tgattggtgt tagaactcca gataatgttt
    24721 tgtttgttgc agatagtctt acaccagaga atataattac taaatatcat tttttcttcc
    24781 tactggatat agattcacag tttaagacac tagaaaaatt gagaatgtta gaggctgatt
    24841 tctttgttcc aagtcactct gtcaaaacta cagatataaa aagtttaatt aatattaata
    24901 agaagaagat ggaagaaata atagataata ttaaaaaggt ttgttatgag ccagttatga
    24961 ttgatgaagt tattgaaaaa atgtgtgatt tgtacaatgt caagcttgat gctaatcaat
    25021 atgtgttggt tggaagtaca atacgttctt atataactta tttatatgag aataatatgg
    25081 ttgaatatat atttgatggt ggtaagatga tgataaaagc tgcgtaaata gtaataattt
    25141 tcaaattata tgatgaaatt gttttagtat gactgttatt tgaaaagtaa tataaaaaaa
    25201 tttatataaa taagctaaga tgattgatat aaagttactg ataattttaa ggtaatatat
    25261 acgttactat aatattatgt tattatttgt aaataagggg ataatttata agcaaattaa
    25321 agaccttaat ttacaggagg aatagtgtat attatgaata aaaaattcaa aaaattcagt
    25381 aaaaaactaa gtatattaat tttagttttg actatgtttc tttttaataa tttaactgca
    25441 aatgcacaga ttaaagaaga ttcaataata ggaattgata gatatgaaac agcaggactt
    25501 atagcggata gacaaactta tgatactgta atattagtta atggagataa aaatttatct
    25561 gatgggcttt catcaagtgg attagctgga gctattaacg caccaatact tttgactaaa
    25621 aaaagtgaaa taccaaaagc tactttaaat agactagata ataagagttt aaatgttgta
    25681 aaaaaagtat atataattgg tggttataat actattgaaa attcagtaga aaaagatata
    25741 aaaagaaaag gtattcaagt ggaaagaata aatggtaaca atagaattga aactagttat
    25801 aatgtagcta aaaaaataaa tgaagtaagt agtgtaaaag aggtaatgct tacaaatgga
    25861 tttgtaggag aggctgatgc tatgagtata gcacctgtag ttgcaaaaaa taaaggagct
    25921 ataatactta cagatgggaa atcagttcca tttaagactg aaggtttaaa tgtttacgct
    25981 ataggtggca aatctgcgat aaatgaggat ttagtaaatg aaactaaagc aattagaatc
    26041 ggaggaaatg atagatttga gaccaataaa aaggtaatgg aaaagtttta taatggagct
    26101 acagattttt atataacaaa tggatatcaa ttagtagatg cactaacatt atctccttta
    26161 gccaaagaaa aaccaatcgt tttagttgct gatggaagta ataaaggtat tttaaaagga
    26221 gctaaaagta taacaaaagt tggaggtatt gatgccaata tatataaaca gtgtttagat
    26281 atgattaaat ataataatat ggatatgact ccaaatattt taaaacactt aacttcagtt
    26341 gaaggaaatg aagtttctga aatacttata gaatcagata atttaggtgt ggttgttgaa
    26401 aagacgaata ccaataaatt tgagtttgat tacgtaagtg taactaatga aaaaaattgt
    26461 actttttctg tatataaaga aaattcttct aataatataa aaaatggaaa gctagttgta
    26521 agtgctaaga aaaaaataga taagaaagat agtgatttgc aagatatgaa tggcgacaat
    26581 atgataaatg caaataaaga taggatggta aatgtgataa aaattggagt tcccgataaa
    26641 atgtattcta attttaaagt agatgttgaa agtggttcag tagaacttta taatattaaa
    26701 ggaggagcta ctgttgatgt caatgacgga attgctaaca ttgttgataa caatgtaaca
    26761 aatcctttca atataaatac taatagtggg atttcaggtg taacagctga aactatatca
    26821 tctgaaataa aatttagagc aaacaatgga attgtaaatg taacagctac aaatataaat
    26881 ggcaatataa gtttatttgg aagcgataat aaagatactt ttgatggaat atttaaatta
    26941 aatctgaaaa aagaaccatc aaatttacac ttgaagttaa ttggaaatgg gataaataaa
    27001 ttgccagaag gttggtctaa agattatatt ttaggaaatg gacaaccaat tattgaagtt
    27061 aaaaataatg gcataaataa tatatcaatt ggagaataaa aacatatgaa aataaagttt
    27121 atatagtttt aaaaattata gaattttaaa atatttatat atattcttta aataaaaaat
    27181 tattttttaa gtgataatta agtgtttatc gataaggcta tggttgtaaa aatcatagcc
    27241 ttatttttat attataaata aattagagta tttatcaatt catagtagat aaaattgaaa
    27301 ttaaatataa caacaaaaaa tgaaaattac aattaattta atgttaaaga ctcaattatt
    27361 tggatgtgga atggatagta caagtagtat ataaaaagta ttgactggac aaataactat
    27421 attttatttt aaatatataa tataatgtaa taaaatatat caaatgtaga aggtgataac
    27481 ctatgaaaaa aataacaata aatgatattg ctaacttggc aggagtatct aaaagtactg
    27541 tatcaagata tctaaacaat aaagatatca gtgattctac taaagagaaa ataaagacaa
    27601 taatagatga atatggatat gagccgaatg catttgctca aagtttgaga gctaaaaaaa
    27661 catattttat tggtattata acaccgtgtt tagattcttt tgtaaaatct aaaattatga
    27721 tggcaataga tgaagaactc aaaaaattaa aatatacatc actaattatt aatactaata
    27781 gaaaaataag gtcagaaata gatagtatat caaagttagc tagtctaaaa gttgatggaa
    27841 taatactaat tggtaccgaa ataactaaag aacataagaa tgaaattgaa aagttagata
    27901 taccgatagt tgtagttgga caaaaagttg atggtatcaa tagcatagtg aatgatgatt
    27961 atggagcagg ctataaaatg ggtcaatata ttgctaataa aggttacaaa aacattgtat
    28021 atttaggtgt tgatgaaagt gatatatcag ttggtttaaa tagaaaaaat ggagtactta
    28081 atgggttaaa agataaaggg tatgatgcaa aagtatttta tactgacttt gaccaagaaa
    28141 tgtctataca aagaagtgga gaaatgctag aaagtgaaaa tccagatata ataatatgtg
    28201 caactgataa tatagcaata gcaacaatga aagaaatcaa taagagaggt aaaagtatac
    28261 cacaagatat atctgtagct ggatttgggg gatatgatgt attgtctatt ataagcccta
    28321 aacttacaac aataaagttt gaaaataaaa atgcaggtaa agtagcagca aatacgatag
    28381 taaatttaat acaagaaaga aaagaaccac tattaaagga gattaaattt gaattaatag
    28441 aaggtgaaag tacaataaat aaaaattaag atacacatta catatattag taatgtgtat
    28501 ttttttacta aaaaaactat aattctaaaa attaggaaaa cttttttgaa agaaatattg
    28561 catctgaaat aaatttatgc taatctttaa ttaaaccggt ttcgaaaccg gtttaattaa
    28621 accgatagaa tagcaaaatg agtgcaaaaa taactgattg taacaaagta tcaaagtaat
    28681 tattggagta cataggaata aacaaaatat aaaagatgta gcacattgtg taataagact
    28741 aagaattgtt ttagatagca ataataaagc aaatataaaa ttataaaaga aaaggaataa
    28801 aaatatgtac aaagagccta aatatagaac catattagaa tcgacaaaag aagaattaaa
    28861 taaattaaga aatatatctt taaatgataa atataaacca ctatttcata tacatccaca
    28921 acatggacta cttaatgacc caaatggatt agcatattat aatggtaagt accatgtatt
    28981 ttatcaatgg tatccatatg atgcaactca tggaatgaag cattgggctt atgtaagttc
    29041 tgatgatttt gtaaactgga atagagaaga tgtagcatta ataccaatcg aaagttatga
    29101 atctcatgga gcatattcag gtaatgcgat agaggtagat ggaaaattgc atatgtatta
    29161 tacagggaat ataaaatata gtgcagaaga tagatatgca tatcaaaact tagctataat
    29221 gaacaaggat ggtaaaataa ctaaatatga aaataatcca atagtaagtg aaataccaaa
    29281 aggatataca ggacatgtaa gagacccaaa agtatttaaa agaaaggata aatactttat
    29341 gttacttgga gcacaaacaa gtgataaaaa aggagttata atagtatatg aatctaaaaa
    29401 ctctatagat tggaatttta aaggagaatt aaatgtaaaa aacatagatg aagattttgg
    29461 ttacatgtgg gaatgtccag attatattaa tatagatgaa aaagatatat taatattttc
    29521 accacaagga gtagaaccta aaggatttga ttatcaaaat atatataatg tagtatatgc
    29581 tattggtaat atggatttag ataatttaac atttgaaata gatacaatga aagaactgga
    29641 aaaaggattt gatttctatg ctccacaaac atttataaag gactcacaaa taatactatt
    29701 tgcatgggct ggaatgggag aagttttata ccctacagat aaaaacaaat gggcacattg
    29761 tctaactgtt ccaagaaaat taaatataaa aaataataag ctattgcaaa tgccagtaga
    29821 tgaattaatt aaattaagat atgatgaaac aagtgggcaa aatactataa agaataatat
    29881 taatattata gaaaatgatg aaaatgtata tgagcttaat attaatataa aaaatattga
    29941 cagcaataaa tttgggctgg aattattttc atcacaagat gaaggtgtaa aattagaatt
    30001 taacaaatta ggaaacattg taactttaga cagaagcaac tttaaaaaag ttttcggtgt
    30061 tgaatatgga acaaatagaa aagaatatat aaatattgat gaaaatacta atatcaaagt
    30121 actagcggat agaagtattt tagaaatttt tataaatgaa ggagaagtag tatttactag
    30181 tagaatattt gctaaagaaa attctaatca aataagggtt tatagtgata aaatagtaga
    30241 gtatgagtat actaaattta aattaaagca aggtattgaa ttataaaaac acattataag
    30301 gggtagaaaa gatgaaaaaa gtaattagta taggagaagc tttaatagac tttataccta
    30361 atcaaaatgg tggtaaatta aaaaatgtat cagaatttag aagagtagca ggaggagctc
    30421 cagcaaatgt tagtgctgtt gtagcaaagc ttggaggaaa atcgagtttt atatctaagt
    30481 taggaaaaga tgcatttggt gattatataa tagatgtatt aaatgaagta aatgtaaata
    30541 ctgattatgt attgagaaca agtaaagcaa atacaggact tgcttttgta tcattaaaag
    30601 aagatggtaa tcgtgatttc tcattttata gaaatccaag tgcagatatg cttttagaag
    30661 ctgatgaagt taaaaaagag tggtttaata attgtcatat cctacatttt tgttcagtag
    30721 atttaataga tagtccaatg aaattagcac ataaaaaagc aatagaatac gcacttgaaa
    30781 gtaatagtat aataagcttt gaccctaata taagattacc tttatgggat agtgagcaat
    30841 cttgtaaaaa ggcaatatca gaatttttac cttttgctca tattgttaag atatctgatg
    30901 aagaattaga atttataaca ggagaaaatg atatagaaaa atcattacat aaactctttg
    30961 tggggaatgt tgaactagta ttatatacaa aaggaaaaga tggagtagat gcatacacta
    31021 aaaaagtaaa aggtatgtgt aaaggggtta aagtaaatgc aatagataca accggagcag
    31081 gagattctta tataggttca tttttataca ccttattgta taaacaaata acattgaatg
    31141 atataaaaga aatgaaacaa gaaacgttaa atgagtattt agaattttct aattattatg
    31201 cagctcgtag tacaactatt aaaggtgcga taagttcata tgcaacaaag gaagaaataa
    31261 ctgaatttat aaaaaattta tagtaggaat gagtaatagg ttttgaagga agtaacatgt
    31321 aaagagtttt taaggatgtt tactatgaaa ataattaaca tataaaaagc aataaggagg
    31381 ctgtctcaaa atagagataa gcctctttat cattgttgaa atgataaaaa atattttaat
    31441 tattgttact ttttagaaga atatatatct tattttaaat aagcaaatta tgtaagattt
    31501 atttatatta tcaatacttt acttggagta ttatgtcttt agcagttatc taattcaatt
    31561 gaattagata aaatataata aatttgtttt gcaaattgac gagaatgttc ttctttttct
    31621 ttattcataa aattaggttt acctaaatca cgttcaacaa gcattcctat atattttaac
    31681 tgtgaatgct tacagtagcg cttcatacca ttttcccaaa tatcagcacc cttttcaggt
    31741 ctatatccac atgttgtaat aagtgctact gattttcctg cccatagagc ggggcctttc
    31801 tcattaccat agtatttatt cattccatac accaatctgt caagtagtgc tttcattgga
    31861 gaagtgcagt accaagaata aattggagta gcaaaaacaa ttaaatcaca cataagaatt
    31921 ttcttgaaaa ttttctgaac atcatcttta caataacatc caaaatcaaa taagttatcc
    31981 tgacactttt tacaagcaat acatggctct attttacaat catataacca tattacttca
    32041 atatttgaat tataattttc taattcctca ataaaaggtt ttaaaatagc agcagtatta
    32101 ccttttttct taggacttcc cataagaatg catacttcca tattgatacc tccacagtat
    32161 tttaaaatag tttttagtgc ttaatatagt tttaggatac tatgagaata cgttaacaac
    32221 aatacacttt gtatatttgt aataaaattg aaacaaattg ttttatcaat aaaagttgga
    32281 atgtatctat aattaaaaat attttaggta tgtttttaca tatatgtgtg tagttaacta
    32341 tggtaattta ttgtaaaatt atcttatagg attataattg cttaatttat gattatattt
    32401 aaaatcttgg aggtaaaaaa tatgtactca aatgaagact ataaatttat agaagaaaat
    32461 gcaccatgtt atatatatga tgagactaat ataattgaaa aatgtaagga attgaaaaat
    32521 aatattttag gttttgattt tttatattct ataaaaacaa atccatataa caaaattgta
    32581 aaaagcattg cagagcaagg ttttggagca gatgcttctt caactaatga agttatgatt
    32641 tcatcaaaat gtggagtttc taaagatgat atttattatt catcaccagg caaaacagag
    32701 attgatatag aaactgtttt agataaatgc ataattattg cagatagtat tacagaaata
    32761 gaacttataa ataagatatc taaaaagcat aatcagaaag ttaaaatagg aataagaata
    32821 aatcctgatt ttactatgga tgatgatagt gctaaatcaa gcaaatttgg tatagatata
    32881 gaagatatga gcagtgtttt taagatgtta agtatgtgtg attatgtatc tgtagttggg
    32941 attcatatac atattaaatc tcaggtattg gattttgaaa agttaggaca ttattatgaa
    33001 aaatgttttt ttatagcttt aaatttaaat aaaagtaagt atattaatat tgaatttata
    33061 aattttggta gtggacttgg agtagcttat gataatctta gagaaaatcc acttaatctt
    33121 aaagagcttt caaaattaac tcaaaagatt gcttttacta attcaaacac actaaaatca
    33181 agacttctta ttgaatcagg acgtttcata gtttgtaaat caggtaatta ttatgttaaa
    33241 attgtagata ttaaagtatc aagagggaaa aaatatctta ttgtaaaaaa tggacttaat
    33301 ggatttatga gacctattat ttctaattta attgaaaata ttacttgtgg agtagaatta
    33361 gaaggtcaag agccattata tacatcaaat catgcctttt ctctttcagt attaaataat
    33421 ttaaaagaag aagagtatgt aaatgttgtt gggaatctct gtacatcatt agatgtaatt
    33481 gcaaataatg ttaaattgaa aaaagcaaac ataggagatt tgatttcaat tagtaatgct
    33541 ggaagttact cctattcttt atcaccgcta ttattttcaa gttatgaatt tcctaaacaa
    33601 tattataaaa gaaaagatgg atatattgag taaacaatag cataaattaa taaacttagt
    33661 attattgaaa aaatttaaaa tgcagggggt gtaattctat atggaattgt ggaaaagaaa
    33721 tttatttgta tgttggatag gtatgttttt tagttctata gggatgagcc aaatagcacc
    33781 tatacttcca ttatatatta aacagttggg ggtaactgat gttagtttaa tacaacagta
    33841 ttcaggtata atttttggat gtacctttgt agtagcagca ttcttttcgc caatttgagg
    33901 gaaagctgct gataaatatg gaagaaaatc aatgctttta cgtgcaagta ttgggatggg
    33961 aatagttata tttaccatgg cgtttgttca aaatgtttat cagttattag gattaagaat
    34021 acttcaagga gtttttacgg gttatgctac tgcatgtact actcttattg caacacagac
    34081 agataaaaat cattcaggat gggctttggg tactcttgca actgcatcaa ctactggctc
    34141 attaattggt ccaacagtag gaggatatat agaatcaatc ttaggtctta aaagtacatt
    34201 tattataaca ggaggattgt tgtttgtatc atttatcatc tctattttat ttgtagtaga
    34261 taattttaaa cctaaagaaa taaaagaatc aatttctata cctaaagaac aattaaatat
    34321 attgccaaat aaatttttaa ttgcatctat ttttgtaacc acattcatta ctcaactagc
    34381 tttatactct atagaaccaa ttgtaaccat atatatatca caacttacaa attttgcatc
    34441 aaatgtagct ttaatagctg gattgacatt ttctgcatca ggattagcaa atttattagc
    34501 agctcaaaaa cttggaaaaa tgtcggataa aataggtcct caaaaagtat tgttaatttc
    34561 acttttatgg gctgggatta tatttatacc acaagctttt gtaaaaactg catggcaact
    34621 gatgttgttg agatttttat tagggttgtc agttgcaggg cttaatcctt ctgttaacag
    34681 cttgcttaaa aaaattgcac cagaagaata tgtgggaaaa atatttggat ataatgcatc
    34741 tgcccagtat ataggctgtt catcaggagc atttttaggg ggacaaatat cagcacattt
    34801 aggtattaga acagtatttt tttcaacaag tttattgttg tttaggaatg cactttggat
    34861 gtataaattt actggattgt ttattaaaga taagactaaa taatcatact atttacattt
    34921 ctaattttat gatgtaaaat aaatattttt tatgtaattt atcatagaat tatataaaaa
    34981 ataaccctat ggtaaaaatt ggaaaatatt attatcgaca aaatctttga cttaaaaact
    35041 atattgcgat agtattaatt taataaaagt ttgagagggg cgtaaggtta tgacaatttc
    35101 aaaaatacca caagcagaat taaaagttat gaagtttatt tgggaaaaaa atgatacagt
    35161 aacatcaaaa gaaactattg aagctatgga acgaaaatat ggttggaaac aaacaactac
    35221 attgacactt ttatcaagac ttgttaaaaa acatttttta agtgcagaaa aaatagatag
    35281 atacactcat tatacaatag ttgttggaca taaggagtat ttaagtgttg agacaaaaga
    35341 ttttttaagc aatatacacg acaattcttt acagagttta atttcagcac tacatgatga
    35401 tgaagttgtt gataaagata tgttggattt atttgaaagt cattttaaaa atttagaaga
    35461 agagtaatta tatcaggata gaactctaag aatttaatta atctatggct gaaaaccata
    35521 aatggtatta tttaatcagc tactcactat tcataaagta atattaaata ggttctctaa
    35581 ttagtaaaat gcctaaaata attggaatag ggagtatcaa gttaaatgat accacttatt
    35641 taaataagaa atgattttta aaatttaaaa taattttata acttgtcaat attcattaat
    35701 ctaaagtatt atttctattt aaccatatca aaatatattt tactattttt aattattaca
    35761 atataaacct gtcttttgtt attataggta aactaaaagt aagaaatgat ttttatattt
    35821 ttaaacttta ttattggtaa cttatctgta aatattttaa aatgtactat agaaagttgt
    35881 taaaaatatt aaataattat attaaattta agtgtgtttt ttatgctata attagtatgt
    35941 attttttatg atatatttta taaaaaatat aatttaatca tttttgagga tattattatg
    36001 ttagatgcat ttataacaat tgtttcttct attatagaaa tatggtcatg taaaaaagtt
    36061 tttgattata ctagtcagtc aaagaccgac ttaaaaaaac taaatatgta ttttctcttt
    36121 tctgtttttc tcattatttc ttctttatat ataaatatag gagctaatag tagaatcttg
    36181 atatgtatat ttgtaatgtt cgttttctat aagtctaact ataaggttaa tatatataaa
    36241 tgtctggtaa tctcattttt ttattggtta atattaatag gtataaatgg attaagtatg
    36301 ttattagtag caacagtaag caatttggat aatatgaatg ttttacttag tggcagttta
    36361 tatagatatg aagcaatatt cttgggaaag ataatgttag gtatattact ttatgtttat
    36421 aaggcttctt ttaaaaattt taaaataagt aaaaaagaga tatacatatg tattcctatg
    36481 atagcaaatt tattgtcatt ttttgtactt tatgattata ttattaatct tgtaaaaatc
    36541 tctcctgaaa gaagaactgc ttttttagta atagttttac tattaatatt atctaacatt
    36601 tcaatctttg tattaataca tataatactt aagattaaaa ttaggaaaat aagataaatt
    36661 ttaatacgat tcatttaaat taaaagttaa taattacttt tttatgtata attttacatg
    36721 aatttctata aaagtta
//
LOCUS       DAGQVA010000040        35455 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.040, whole genome shotgun sequence.
ACCESSION   DAGQVA010000040 DAGQVA010000000
VERSION     DAGQVA010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35455
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.040"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            161..727
                     /locus_tag="MIV85_002111"
     CDS             161..727
                     /locus_tag="MIV85_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBY2961445.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            1032..1493
                     /locus_tag="MIV85_002112"
     CDS             1032..1493
                     /locus_tag="MIV85_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2961446.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1561..3807
                     /locus_tag="MIV85_002113"
     CDS             1561..3807
                     /locus_tag="MIV85_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961447.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3800..5632
                     /locus_tag="MIV85_002114"
     CDS             3800..5632
                     /locus_tag="MIV85_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961448.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVE
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6351..7628
                     /gene="hflX"
                     /locus_tag="MIV85_002115"
     CDS             6351..7628
                     /gene="hflX"
                     /locus_tag="MIV85_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBY2961449.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVDVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     MSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7861..8358
                     /locus_tag="MIV85_002116"
     CDS             7861..8358
                     /locus_tag="MIV85_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2961450.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8408..8932
                     /locus_tag="MIV85_002117"
     CDS             8408..8932
                     /locus_tag="MIV85_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBY2961451.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            9244..10608
                     /locus_tag="MIV85_002118"
     CDS             9244..10608
                     /locus_tag="MIV85_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBY2961452.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLVAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            10747..11913
                     /locus_tag="MIV85_002119"
     CDS             10747..11913
                     /locus_tag="MIV85_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBY2961453.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            12030..12812
                     /locus_tag="MIV85_002120"
     CDS             12030..12812
                     /locus_tag="MIV85_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBY2961454.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(12931..13584)
                     /locus_tag="MIV85_002121"
     CDS             complement(12931..13584)
                     /locus_tag="MIV85_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2961455.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(13608..14972)
                     /locus_tag="MIV85_002122"
     CDS             complement(13608..14972)
                     /locus_tag="MIV85_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBY2961456.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            15631..17061
                     /locus_tag="MIV85_002123"
     CDS             15631..17061
                     /locus_tag="MIV85_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2961457.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            17164..18267
                     /locus_tag="MIV85_002124"
     CDS             17164..18267
                     /locus_tag="MIV85_002124"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBY2961458.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            18282..18518
                     /locus_tag="MIV85_002125"
     CDS             18282..18518
                     /locus_tag="MIV85_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2961459.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            18535..19584
                     /gene="vorB"
                     /locus_tag="MIV85_002126"
     CDS             18535..19584
                     /gene="vorB"
                     /locus_tag="MIV85_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBY2961460.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALTSKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            19586..20326
                     /locus_tag="MIV85_002127"
     CDS             19586..20326
                     /locus_tag="MIV85_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBY2961461.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            20329..20868
                     /locus_tag="MIV85_002128"
     CDS             20329..20868
                     /locus_tag="MIV85_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBY2961462.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            20992..23091
                     /locus_tag="MIV85_002129"
     CDS             20992..23091
                     /locus_tag="MIV85_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBY2961463.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIENRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(23358..23873)
                     /locus_tag="MIV85_002130"
     CDS             complement(23358..23873)
                     /locus_tag="MIV85_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBY2961464.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(23965..25176)
                     /locus_tag="MIV85_002131"
     CDS             complement(23965..25176)
                     /locus_tag="MIV85_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBY2961465.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            25852..27294
                     /locus_tag="MIV85_002132"
     CDS             25852..27294
                     /locus_tag="MIV85_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBY2961466.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            27336..27689
                     /locus_tag="MIV85_002133"
     CDS             27336..27689
                     /locus_tag="MIV85_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961467.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            27880..28701
                     /locus_tag="MIV85_002134"
     CDS             27880..28701
                     /locus_tag="MIV85_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBY2961468.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            28959..30842
                     /locus_tag="MIV85_002135"
     CDS             28959..30842
                     /locus_tag="MIV85_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBY2961469.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            31067..31747
                     /gene="pgmB"
                     /locus_tag="MIV85_002136"
     CDS             31067..31747
                     /gene="pgmB"
                     /locus_tag="MIV85_002136"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBY2961470.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            31744..34029
                     /locus_tag="MIV85_002137"
     CDS             31744..34029
                     /locus_tag="MIV85_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBY2961471.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGR
                     PIKIIVYGKKYILEKCIKIDK"
     gene            34254..35147
                     /locus_tag="MIV85_002138"
     CDS             34254..35147
                     /locus_tag="MIV85_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBY2961472.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYSNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
BASE COUNT        13868 a         3846 c         6178 g        11563 t
ORIGIN      
        1 atatacaaat acttataaat acaagttata tacaagattt atagtagagt aataatctta
       61 taaaataatt taataaatat aaattaaatt atatgtgtat atattgtact ttaatagtga
      121 tataataata aaaaaatttt taaagagggt gatattacat atgagaaaac ttgaagagat
      181 attagaatat aataaatcat ttgtagagaa caaagaatat gaacaatatg tgacatcaaa
      241 acatccaaat aaaaaaatag tagtcttatc ttgtatggat acaagattaa ctgagctttt
      301 gcctaaggct atgaatttga aaaatggaga tgtgaaacta ataaaaaatg caggagctac
      361 tataatgcat ccttttggaa gtattatgag aagtgtttta gttgcaattt acgaatttga
      421 tgtagatgag gttatggttg tagggcatca tggatgtggt atgtgtaatg ttgatacgga
      481 taagttactt ggtaaaattt tagatagagg aatatctaat gatgtaatac ttacacttcg
      541 tagtgctgga attgatacaa aacaatggtt acatggattc gattctgcag aagaatctgt
      601 aaaagatagt attgatttaa taaaagggca tcctttaatt ccagatggta ttattgtaca
      661 tggtctaatt atatcacctg aaactgggaa gttagatgtt gttgtaaatg gatatgaaga
      721 taagtagagt atcataatgt tatataatca agatactgtt gaataagatg ttgtttcaaa
      781 atttattttg ggacaacttt tttatttgaa aatatatgaa aaggtttatt ttaagcttta
      841 caataaaaaa tataagtagc tgactaatta aaaatcttac tattatttat taaaattata
      901 actatatgat ataaaaatat ttaataaatg aaatttatat gaatttttta taaatatatt
      961 gaaaaaatgc atgcagtata gtaaaataat gcttagccga ctaagtaata taaaaaataa
     1021 ggagggcaag tatgaatagc aattctgaag aaaaattaaa tgatgttttc ttgcaattaa
     1081 tgcgaatata ttttataaga actcattttt attttgataa attaggctta tatcatggtc
     1141 aaccccaaat acttttttct ttaaagatga aagatgggca aagtcaaaaa gaattagcag
     1201 ataaaaggaa agtaaaagca tctacaacta cagttatgat aaagaggatg gaaaaagctg
     1261 gacttgtgga aagaaaacaa gatgaaaagg accaaagagt atctaggatt tttttgacag
     1321 acaaaggttt agaaatatgt aataaagttg aagaatttaa caaggaattg gaaagagagt
     1381 tttttttagg atttagtgaa gaagaaaaaa tagtacttag aagacttcta atgcaagtac
     1441 gagataattt aaaagcagga tgtcataagc atgaagatga aaaatatttt taaagtttaa
     1501 aataatgttt ttcaatttaa tgttattaga ctaattaata ttacagaagg gaagaaatgt
     1561 atgtttaaat taattaaata tttaaagaaa tcggcattat caatagtaat aatagtctgt
     1621 ctattggtaa ttcaagcggt atgtgacctt tctttaccag aatacacatc caatatagta
     1681 aatgtaggta tacaacaagg tggagtagaa aactctgttc catctgtgat tagagagagt
     1741 gaattaaata aaattacttt atttatggat aaaagtagta aggataaagt actagataat
     1801 tatactttgc tgaataaaaa ggattatgtt aagtataaag ataagtaccc aggtctaaaa
     1861 gatgaatctc tttatgagtt aaatactaaa gacaaagaca ctatagatga tttaaatgtt
     1921 atttttggta aagctatttt aatagtatca gggcttgagg gcgatagtaa agaggtaaaa
     1981 gctatgaaag ctcagttaat gagtaaactt ccaccacaag ctactcaaag tggagatgtt
     2041 gatatattta aattgttatc agcaatgcca aaggaacagt tagatacatt gactaaagag
     2101 atgagcaaag gctttgaaag tatgccagag agtatgataa cacaaagctc tgtttcatat
     2161 gtaaggtcag aatatgagaa aataggtatt gatacagaaa aaactcaaaa taattatata
     2221 ttatttactg gtgctaaaat gcttggtata gcaatgatta gtatggtagc tacaataaca
     2281 gtaggatttt tagcagcaag agtagccgca agtgtaggta gaaatttaag aagtggagta
     2341 tttagaaaag ttatgtcatt ttcaaatact gaaatgaatg aattttctac agcttcatta
     2401 attactcgta gtacaaatga tattcaacag atacaaatgt tgatggttat gttgcttaga
     2461 atagtattct atgcacctat aatggctata ggtggagtga taaaggtttt aaacacaaat
     2521 acttcaatgg cctggattat agcagtagca gtagttgcta tcttatcatt aattgtagtg
     2581 ttattctcag tggttatgcc taagtttaaa ctggttcaaa agcttgttga taagttaaac
     2641 ttagtaagcc gtgaaataat tactggtatt ccagttatca gagcttttag tactgaaaaa
     2701 catgaagaag aaagatttga taaagcaaat aaaaatttaa ctaaaacaaa tctttttgta
     2761 aatagagtta tgacatgtat gatgcctgct atgatgctta taatgaacct tatcacagtt
     2821 cttatagttt ggagaggtgc atacagtgtt gattctggag caatgcaagt tggagatatg
     2881 atggcattta tacaatatac aatgcaaata ataatgtcat tcttaatgat atcaatggta
     2941 tctattatgc ttccaagagc atccgtttca gctacacgta tagatgaagt attagtgtca
     3001 gatataagca taaaagaccc agaaaaatca gaggcacaag agtttaagga agataaaaag
     3061 ggtcttgttg aatttaaaaa tgtttcgttc atgtatccag acgcagaaga acctatatta
     3121 acaaatatat cttttacagc aaagccagga gaaacaactg cctttatagg aagtactggt
     3181 agtggtaagt caactcttat aaatttaatt cctcgtttct ttgatgttac tgaaggagaa
     3241 atattacttg gtggagttaa tataaaaaat gtttctcaac atgatttaag ggaaaaaatt
     3301 ggatatgtac ctcaaaaggg agtattgttt tctggtacta tagaatccaa cttaaaatat
     3361 ggtagaaaag acgcaacaga tgaagaaatg agaacagcag ctgaaatagc tcaagctaca
     3421 gaatttatag attctaaacc ggaagctttt aaaactgaaa tttctcaagg tggaacaaat
     3481 gtatctggag gtcaaaaaca aagactttct attgcaagag caatagcaaa aaatccagaa
     3541 gtttatatat ttgatgatag tttttcagca cttgacttaa aaactgatgc agctcttcgt
     3601 aaggctttaa aatcaaaaac tgctgaaagt acagttctaa tagttgcaca aagaattagt
     3661 actatcttaa atgcagaaca gataattgtt ttaaatgagg gcgaaatagt tggaatagga
     3721 acacataaag agcttctaaa aaattgcgaa gtttatgagc aaatagcttt atcacaactt
     3781 tcaaaggagg agctagctaa tgagtagaat gggaagaggt cctatgggaa aatctatggg
     3841 agcaggacaa aaagcaaatg actttaaagg gactatgcga aaactaattg catatttatc
     3901 taaatttaaa atatcaataa ttctagtaat tgtatttgct attggtagtg cgtcgttttc
     3961 tatagtaggt ccaaaaattt taggaaaggc aactacaaag atatttgaag ggctagtgag
     4021 taaagtttct ggaggaaacg taggtataga ttttaatgca attggaaaaa tcttaacctt
     4081 tttacttttc ctttatttga taagtgcact gttctctttt atacaaggat ttataatgag
     4141 tggaatttct caaaaagtat cctataattt aagaaaagag atttcagcaa aattggatag
     4201 attgccaatg aagtattttg atactaagac gcatggtgaa atattatcga gaattacgaa
     4261 tgatatagat actttaaatc aaagtttaaa tcaaagtatg acacagctta taacatcagt
     4321 aacaactatg ataggtgttt tgataatgat gttatctata agtggaatta tgacattagt
     4381 ggcagtttta atattaccaa tatcaatgtt tgtaatttca agaataataa agaaatcaca
     4441 aaaatacttt agatatcaac aagaatattt aggaaatgta aatggtcaag ttgaggaaac
     4501 ttacagtggc caaacaatag taaaagcatt taatcgtgag gatgaagtaa ttgaagagtt
     4561 tgataaacta aatgatagcc tgtataattc agcgtggaaa tctcaatttt tatcaggtat
     4621 aatgcaacca cttatgatgt ttattggaaa cttgggatat gtaatggtat caatcttagg
     4681 aggttggctt gcaattaaga aaacaattga ggttggtgac atacagtcat ttatacaata
     4741 tgtaagaaac tttacacagc caatgactca gattgcacag gttgccaatt tattgcaatc
     4801 aacagcagca gcttctgaaa gagtatttga gtttttagaa gaggaagaag aagtccaaat
     4861 tgttgaaaat gcagtttcaa tagatggttt agaaggtaaa attgattttg aaaatgtcaa
     4921 ctttggatat aacccaaaca agactataat aaatgatttc tcagtaaatg ttgaacctgg
     4981 tcaaaaagtt gctattgttg gacctacagg agcaggtaaa actacaatag ttaaactgtt
     5041 aatgagattt tatgatgtta atagcggttc aatactgatt gatggtcata atattaaaga
     5101 ttttaatcgt agtgagctta gagaaatgtt tggtatggtt cttcaagata catggttatt
     5161 tagtggttca attatggaaa atataagata tggtaagttg aatgctacag atgaagaagt
     5221 tatagaggct gctaaatctg cacatgttca tagatttatt aagacattac cagatggata
     5281 taagatgaaa ttaaatgaag aagcaagtaa tgtttctcaa ggtcaaaaac aattattgac
     5341 tatagctcgt gctattttag ctgatcctaa aattttaata ttagatgaag ctacaagttc
     5401 tgtcgatact agaacagaag tattgattca aaaagctatg gataatctta tggaaggtag
     5461 aacaagtttt gttatagccc acagattatc aactatacgt gatgctgata tgattcttgt
     5521 aatgaatgaa ggagatatag ttgaacaagg aaatcatgag gaacttctaa agaaaggcgg
     5581 attctatgcc aatctttaca attctcaatt tgaagaagat gaagcaatgt aacaaaaaac
     5641 tatcttagca tagacatgta attaataaga taaaataaat gagggtgcct taaaatgaac
     5701 tttttaattc ataaggcact cttttgtgta tgaaataaag tgtattttta tcattttaac
     5761 aatgaaaaag aggattctct atattttgag atagccacat aattttatgt ctttacaaag
     5821 tgtttatttt attataatat gtagtaagga aaatgttgga ggtgattatc aaaatgtata
     5881 tttaatttta ttctttaaat tttattataa atagaattta attttaatag ttgatgatta
     5941 tattgaagta tatgttttta ttacttttat taatcatgca aataactact taaatttaag
     6001 aatagggtta aatataaaat gataattaca tataagttaa ttaaactaat gtatttttaa
     6061 tatatattta gaattttaat ccttcttatg atataagtag cttgttttgt attacttaga
     6121 tttgtaagga gtttttttat tgaaaaaact gcataatata tttgggagga ggtgtaagaa
     6181 agtgattttt tatataagat tgagaaaata atgcacgatt atggttatta taatagtaaa
     6241 taagaagtgt catttaagga taagataaaa agcaaaattc ttgatgaatt taattataga
     6301 gccataatct cgtgctatag attaaataaa aaatagcaga taaggagaat atggatatgg
     6361 cgaaaaaagg aataacagta ggattaaaca taaataataa atctgaggac tttaatgaac
     6421 taatgattga acttgaaaac ttatgttcag catgtgatat tgatgttgta gggagtataa
     6481 ctcaaaatgc aaagcaggtt aatagagcat tttacattgg gacaggtaaa gttgaggaaa
     6541 tattaaactt aataaagaaa gaaaatatag agatagttat attttacaat gaactttcta
     6601 catcacaact aaaaaatctt gaagaaaagc ttaattgtga aattatagat agaacggcat
     6661 tgatacttga tatatttgca caaagggcaa aaactagaga agctaaactt caagtagaag
     6721 tagcaagttt aaaatatatg ttaccaagac ttataggttc aaatgaaaat ttaggacgtc
     6781 aaagtggtgg agttggtact aaaaatagag gttctggtga gaaaaaatta gaacttgacc
     6841 gtagaagaat agaagaaaag ataacatctt taaataggga gttggatgat ttaaaattcc
     6901 aaagagaaac tcaaagaagt atgagaagaa aatcaaatct tccaaatgta gctctagtcg
     6961 ggtatacaaa tgctggtaaa tcttcaataa tgaataaact agtagatata tttaaaaact
     7021 ctgaagaaaa gaaagtgttt gagaaaaaca tgttatttgc tacacttgaa acttctgtca
     7081 gaaatatagt tcttgcaaat aacaaagaat ttttattatc tgatactgtt ggttttgtaa
     7141 gtaatctacc acatgactta gtaaaagcat ttaggtcaac attagaagaa gcatgtgagg
     7201 cagacgtact gttacatgtt attgatattt caaatccaag ctataaaagt catattaaag
     7261 tgacagaaga tactttaaaa caaataggtg cagatggtat acctatgata catgtgtata
     7321 ataaaattga tttaatagat gtagacgtat tggatagaat tttagatagt attgataaag
     7381 aaggtatatt tgtttcagtt aaaaaagata taaatataga taaaatgata aaatgtattt
     7441 gtgatagcat atttaaagat tatgtaagat gtaagttctt aattccatat gataaaggtc
     7501 atgtagtttc ttattttaac gaaaatatga gcattataaa tacagaatac agagaagatg
     7561 gagctatttt agatgtagaa tgtagcaata tagaatataa taagtataaa aagtatgctt
     7621 tagagtaaat tttgaaaaac ttattatagc ctaaaatata tttaatttat aatttattat
     7681 aaattgattg taaatatgat tttatgaaac ggtatagcca taatgctatg ccgttttgcc
     7741 atttataata aaaataaatt tattgacata atagtaacta attactataa tataaagtaa
     7801 ttagttacta tttaaaatta tcaaaaaatt aaaatctaag ataaagagaa gtgtataata
     7861 atggatgcag aaactttaat gaaaaaatat atggtagatg atgatagtag aaaacaagct
     7921 atatttgcaa gtatatttgt aatgcaaaat aaacttcaaa ctacatgtga taaattagac
     7981 ccagaattaa caatgaaaca atggttactt ttagctattg cggactctgt agatgaaact
     8041 cttacattaa ccaaacttgg agaattaatg gggtgctcaa gacaaaatgt aaaaaaacta
     8101 gctattgctt tagaaaagaa aggttttata caaattgagc agaatgaaaa agattcaaga
     8161 gctatctgtc ttgtgacaaa agatagagtg caagagtatt ctaaaaaagt aagaggtatg
     8221 caggaaaaag tattacagct tttatttgaa gattttacag agaaagaagt ggaacagtta
     8281 ttttttggaa ttatgaaatt aagtatagga attgaaaatg tgaaaaatta tgtagaaaat
     8341 aatgacgttg gagaataagc aagtatcaaa tcaactttgt atgacatcag agagggggat
     8401 aatttatatg aaaaatgtag tagtgattta taagagtaag tatggttcaa caaaaaaata
     8461 tgctaaatgg ctttcagaat tattgtcttg tgatattttt gaaactaaga atattaatat
     8521 agaaaaggtt atgaagtatg atacgattat tttaggagga ggtctttatg cttgtaatat
     8581 agcgggaatt tctttcttaa aaaaaaatta taaagaattg cagaaaaaaa atttagtagt
     8641 atttggcgta ggagctgctc catatgatga tgaagtaata aagaaattaa gagaagtaaa
     8701 ttttaaggat gaattaaaca aaattccttg cttttattgt cgtggggcat gggatgagac
     8761 aaaaatgtct tttatagatt atactctttg tagttttttt aaaaaatcta tagctaaaaa
     8821 agaacgtcaa ggtcttaaac cagcagaagc acctttattg tctggagaag catttgattg
     8881 gtgtaataaa gaaaatttaa ctccaatact tgattatata agagaacttt aagaggtata
     8941 tatttataat tatttattat ctaaagttag atttcataga aacttactag acattattta
     9001 taaaataata ttattaaaga tggataattt aattgattca ataaggttat aattttaaaa
     9061 aatgtttatt ttaaaataaa ttattttata agcttactta tacttaataa ggggcttttt
     9121 ttattggaag atttatgtta tattgagatg aatttattat gatataaaaa ataatgttag
     9181 gataaattta aatctttttc taaaaatgta ttaatataat tcttaaagaa aggattttta
     9241 ataatggata taaaagagtt agttaaaatg caaagaaaat attataatac aggtaaaaca
     9301 agagatatat cgtttcgtat agaacagttg aagaaactta agttagttgt atcacaaaat
     9361 gaagaaaaaa tacttttagc actaaagaaa gatttaaata aatcggattt tgaaggtttt
     9421 atgacagaag taggcatgtt ttatagtgaa ttaaactttg ctataaagaa tataagaaaa
     9481 tggagcaaaa taaaaagagt taaatcaagt atggttaatt ttccatctat atccaaagtt
     9541 gttccacaac cttatggtgt tactctcata atgtcacctt ggaattatcc atttcaatta
     9601 gcacttatac cattagtttg gtcattagta gcagggaatt gtgttatatt aaaaccttct
     9661 gaatattctg tgtcaacatc tagtgtagtt aaagacatag tggaagatac tttttcaaaa
     9721 gaatatgttg cagttgttca aggaagtcaa gaagaaagtg aaaagttact attggaaaga
     9781 tttgattata tattttttac aggaagtact aatgttggta aaataatcat gaaatcagca
     9841 tcagagcatt taactcctat tactttagaa cttggaggaa aaagtccttg tatcatttta
     9901 aaagatgcta atatagacct tactgccaaa agacttactt ggggaaaact aataaatgca
     9961 ggacaaacct gcgtggctcc agattatgtt ttagtgcatg aagatagaaa aaatgagtta
    10021 atagagaaaa taaaatatta tactaataag tattttggag ataatccatg taataatgag
    10081 caatttccta aaatcataaa tcagagacat tttaatcgga tattatctct tattgataaa
    10141 gataagatag tctatggtgg aaattataat aaggagacat taaagataga gccaactata
    10201 gtagacaatg ttaattggga tgataatata atgaaggaag aaatatttgg gcctatattt
    10261 cccattttaa catataaaga tttagatgaa gtaatacaaa aaattataca aatgccaaat
    10321 ccattggcac tttatatttt tacaaaaaat aagtacctag aaaataaact tttagaaatg
    10381 attccagcag gcggatgttg tatcaatgat acagttactc atatagctac gaattactta
    10441 ccttttggtg gtattggtga aagtggtatg ggctcatatc atggaaaagc tggattcgat
    10501 acatttactc actataagag tgtgttaaaa aaattaaatt tggatgtccc tattagatat
    10561 gctccatacg ataataaatt aattaaggtt cttaaaaaga taatgtaggt tatattgtag
    10621 aataataaat ataaataaaa ttgagtattt gtattctgaa tatattttat ttttaatttg
    10681 gtatatttgt tataaaagtg gtgattttgt gataaaattt aattatatag aaataaggag
    10741 gaaaaaatga aaattaattg gaatacaaaa tacacaacaa tagcaattta tacatttata
    10801 atagctgcta gtagtattat attttatcta gtatcatcac aaattgatgt attttctaat
    10861 aatttagatg ctatatttac aacattacaa ccttttataa taggatttgc tattgcatat
    10921 cttcttaatt ttattttaaa gttttatgaa gacagaattt ttataaaaag tgagaaatta
    10981 aaaaaactaa aacaaagttc aaaaagaggc ttgggtcttt tattaacata tgcaacagct
    11041 acattgatac tttacttatt tatgcatttc gtattgccac aagtaattga gagtattgtt
    11101 ggactagcaa atgatatacc tatgtatgta aacaatgcaa ctaagcttat tgataaatta
    11161 atgactgatt taaatcttga tgagcaatac tttaatttgg cagttgataa gtggaatgag
    11221 tttgttacat atattataaa gtttgtaaca gatttaatcc caatattagg aagtatgtta
    11281 aagaatgtag cctctagtat atggaatatt gtactaggat taattgtttc agtatactta
    11341 ttaattgata aagaaaaatt ctatggatta agcaaaaaaa taacttatgc agtatttaca
    11401 gaaaaacaag ctgccagaat tttagaatta actcatagaa gtaactatac atttggaaga
    11461 tttttaggtg gcaaaatatt agattcattc attataggta ttctaacatt tgtaatactt
    11521 acgttagtta aaatgccata tacattatta atatcagtta taattggtat tacaaatatt
    11581 atccctttct ttggaccttt atttggagct ataccatcta cgctaatagt gatgtttgta
    11641 tctcctataa aagctttctg gttattgttg attatattaa taatacaaca gatagatgga
    11701 aatattatag gacctaaaat acttggagat tcaattggta tatctgcatt ttggattttg
    11761 ttctccttat tggttgcagg aaaattatta ggttttattg gaatggttat aggagttcca
    11821 atgtttgcag taatttattc tataattaag gatattgttg aaagtaaatt ggataaaaag
    11881 ggattaccga cagatacttc cgattatatg tagctaaaaa atattatgta taattaaaaa
    11941 tatataaatt aagcaatatt taaagcactg agaaagttaa actcttggtg ctttttagat
    12001 ataaaattat tatagaagag gtgttttttg tggcatttat agaatgtaaa tttaaatcta
    12061 aatatactgg aggagaaact gatataattg taattttgcc tgtagcaaat ggaaaagaac
    12121 tttttagtgg taaagagata tatgattttg aaggtaaatt taaaacatta tacttatttc
    12181 atggtttaga agatgaccaa agctcatgga ttagatatac taatgtagag cattatgcta
    12241 aaaataaaaa tatagcccta gtaataccaa gagtagaaac tagtttttat accgatatgg
    12301 cgtatggaca ccaatatttt acttttgtaa gcgaggaatt acctaaattt gttagagcta
    12361 tatttccttt atcagataaa agggaagata actttgtagc tggtatgtct atggggggat
    12421 atggagcttt aaaattagcg ctttcaaaac caaaagagtt ttcggcagtt gcaagttttt
    12481 ctggttcgcc tgatatgatt catgagttag aaaatcaaca aatagaaacc aatgcagaca
    12541 ttctatttca cgattttggt agaccagaag acgctagaaa tagtgagaat gatttacttt
    12601 acatacttaa gaaccttaaa gaaagaaatg aagatattcc taaaatttat caattttgtg
    12661 gtgatagaga ttttttatat aaaaataatc agatgtttaa aaaatatgca gattctctgg
    12721 gtgtagatgt tgaatatgaa gagtgtgtag gggggcatga atggcgtctt tggaatttat
    12781 ggataaagaa atttatagat ataattggat agtacactta tggtattaac aggtatacta
    12841 taaaatatct ttaaatatga taaagactga aatcctaaaa tcaaattatg attttaaaat
    12901 ttcagtctct aagaatttaa taaaatttta ttaagttctt acacgagtta ttattggagt
    12961 aaaattgtca actatatcta tatagtattt actcaattcc tctaaaatct cttcgcataa
    13021 atccgtacta tgaccaagat taataagaaa ctgttttgta aaatgcttta ttacagcttg
    13081 agaagatata tcgtacttgt gtgaagtata aactctaatt atttcaggtt tcatagcaag
    13141 tataccaata caagaaagta ttaattcatc atgttctata gattctttat cattaacata
    13201 tcttttcatg accatttcgg ttacacttct ttgatagctt aaaatagctt cttcataagc
    13261 tatatccaaa taaaaatttc tatatgcttc gttttttaga aggaaacaaa ggtcagcatt
    13321 catagcaaga aagaacatca tcatagtacc ttcttcatgg tagttataga ttaaagactg
    13381 catttcattt cttatatctt catatattat agctcctatt tcgcttttac ttgagaagta
    13441 atagcttatt agacctaaat ttatattagc tctttctgca atttgcctag ttgttgtctt
    13501 atgataacct tgctcaaaaa ataattctct agcagcactt ataatactag cttttgtttc
    13561 tttgcccttt tctgattttg acatatttac tgtgtatacc tctcttttca atcttttttt
    13621 gaaaatttgc taactataaa tattgtaata gaaccaccta ttataggaac caaaattctg
    13681 tcaaatacag taagaatacc aatcatattt aataatgcca atataacact tactataaca
    13741 gcatagatag ctcctttttt tgtagcacct ttccagcaaa gaccaattac aaatggtgca
    13801 aatattacac ctgtacataa tggagctggc caaaacaata attctaataa actatcaaat
    13861 ttaagtgcta tgattgcacc tattatagct gtcaaagctg atgcaatttg agaatacttt
    13921 agagtatttt ttaaatcatt aaattctata ttaggatgta ataatttgtt ataaatatct
    13981 cttgatataa tagcactcat tgaggtcatt aatgaatcgg cagtagacat tatggcagcc
    14041 aatatagcag ctaagaataa tacagatatt aaaggtggca aagtagtcga tatcatttga
    14101 ggtaaaacct gaacagatga tatatttgga aataaactac caccaatagc tccaattatt
    14161 cctataggga aagcaagaaa taatagtata aatcctgcaa ttacactact tttaactgca
    14221 tttttagcat tatcagcaca ttgatatctt aaaaaacttt cataagaaaa tattgagcct
    14281 aaaactaatg gtaaaactgt atacataaaa tcactaatcg atttatttcc tggaaagaat
    14341 ggttctttta ccattgattg taacataagt aaagggttgt cgccaactaa ttttaagctt
    14401 atataagcta ctattggcaa aaacactata caaatagcaa gttgaataaa tgctgatact
    14461 gcaactcccc acattcctga tgtataagta tatataatga taactataac tcctataatt
    14521 acagctatat cataaggaat accaaatgca gtagatacag aaccaaaaga aatcaattga
    14581 ctacccataa tagctagtat agatattggt gttacaagac tttgataagc tcttaaaaat
    14641 acactatgac catatctagt ttcaatataa tcagcaggtg ttatatcaca agataagctt
    14701 cttaattttc ctgcgaaaaa tgcatttata aagcaagcta aagctgcacc tatagtagaa
    14761 tacattccaa cccaaagtcc tctttcagct ccccattgaa ctccaccaac taagcaccct
    14821 cctccaaaag atgtagcagc aatggttgca gctagtatag gcaaaggcag atttctacct
    14881 gcgattagga aatcggatgc tgttttaact ttttttgaaa aataaaaacc aatccatatg
    14941 tatattgcac acgtaacaat taaaagtaac atagtctttt ctcctttata aaatatttta
    15001 ataaaatata caaaatatat ttaaaatata ttttatataa aagtagtacg atatttgttt
    15061 tattggtttt agattaatat agctataata atttatgata ttagatggaa attacgtaaa
    15121 aatagaaaat tgaaaattct gaaatttttg tatattgata tttatctcat agattctttt
    15181 ttgtaattgt aacacgcttt tatttttaaa tcaatagtac atgtataaaa ataaaaggaa
    15241 tttaaataag aaaaagatat ttttaatatc tggatgtagt atagaaatat cttgaataaa
    15301 ttattcttga ataaaattat aaaaaattaa aatcactaga aatatgataa aataatttaa
    15361 aatacgcatt tcaatgacat ttcaaaacaa taaaataata aaaaacaaac ctaaattaag
    15421 tctaaatagc tttttagtta attttagtag taaaaaataa aacttaaaaa gtgtttgaca
    15481 attatgaatt ttgagaatat aattaaatta aaattataca catataaaaa tatactcctg
    15541 aatcaagaat gagatattta agattcaaaa tatatattat tatacgtgaa taataaaaaa
    15601 gtaagaaaat tttataaggg aggggtagat gtgagtagtc aagaaagcaa accaaaagga
    15661 aatcttatat caaattttag agatgatatg agagacccta agaaaagagc aatatacaca
    15721 tattcaagtt ctataaactt agcgtacaat tttataggtt actttgtatc aactgttaca
    15781 aatatttttt taactgatgt ggcaaaactt ggtgtaatta tggcaggtgg tatgcaaatt
    15841 atacaatctt tcataaaaat tgctgtagct cctataacag gtacagtatt tgacaaacaa
    15901 ccattcaaaa aaggaaagta ttatccatgg cttagatatg caccagcagc gttagcatta
    15961 acatatggaa tatttttcat agttccatta atgaaaataa gtccagcatt acttttacct
    16021 ttgatgacag ctttattatt aatagcatct tgtgctcagc aagtagtttt cactataatt
    16081 tatgctattt accctgtagt tgctaagaca cctagagacc gagttatagg ctcaactact
    16141 acgaatatat ttaaagaagt tggtaaattc ttagtaggtt tttcatatcc gttattatta
    16201 gttttatttg cagatgtatt aggtggagaa ggaatgggtt atttaggtac ctacttattc
    16261 tttgcagcag gatgcctttt agtattttgg ttttcttcaa cagagataat aaaatctgga
    16321 gcagaagaag aagttcttca aaaagaagag aagccaaaga ttaaagcaag tgaaatggca
    16381 aaagctttat tcactaatgt accacttatg atggcatttt gtttagaatt tcttatatgt
    16441 ataagatcta taggattagg acctttggct ccatattatt ttaaatatgt aatagaagat
    16501 gaacgtggat tagcagtatt tttatcaatc atgcctttgg taagtgtagc attcatgttt
    16561 ttcgcaccag tgtttataaa aatctgtaga gagcaaaaac tagcttcaat aatttctttt
    16621 tctatatgtg cactatgcca cttattggtt gcatggactc cttgggggaa aactacttta
    16681 ggagtaacta tgttgctggc aattggtgga ggtttttcaa atgtagtatc aataataaat
    16741 cttaatttct ttgccggttc ttgtgattat gggcattgga aatcaggaaa agacttacct
    16801 ggcttaagta tgtcactata tccagttgca atacaagtag gagtattact tgcaactact
    16861 ataagaacag ttttaatgaa ctcaatggga tatcaagctg atatggtagt cacagaagca
    16921 gttaaatcag gttttataaa tatgatttct tattctatgg caataccttt aataatagct
    16981 gttgttatag caatactata tccagtaagt gacaagaaat taaaccaaat aagagaagag
    17041 ttaaatcaaa gaaatgctta gttaaaagaa agttaagtag atggttaatt taagctatta
    17101 aagtaagtag acgcaatagc gtttatataa atgaaaatac atatacagag ggggctttta
    17161 aaaatgatag aaaaattatt gagaaatacc gtaaaagaat tacatcaata tgttccaggt
    17221 gaaccaatag aaaaagttaa ggaaaaatat ggtgtaaaag aaataataaa attagcttca
    17281 aatgaaaatc ctctaggacc atcaccaaaa gcaatagaag ctatgattga aatgttaaaa
    17341 caaggtcaac tttatccaga gccagaagct aacgaactta gaagaaaatt agctgaaaag
    17401 ctagatttaa aaccagaaaa ttttattgtt gctaatggtg cagataacgt tatcactcta
    17461 ataggtgagg cttttataaa tagaggagat gaagttatat attgtaaccc aacatttcca
    17521 tcatatagaa ctgcaactat aaaaaatgaa gggataccag tagaagtacc tttaacagaa
    17581 gattataagt atgatttaca aggtatatta gataagatta cagataaaac aaaattaata
    17641 tgtgtatgta accctaataa tccaacagga acaattgtgg atgataaaga gttagaagaa
    17701 tttttaaaga aagtccctga aaatattata actatattgg atgaagcata tatagaattt
    17761 ttaacagttc ctaattatgt ggatggactt aagtatgtaa gggaaaatta taacgttata
    17821 gtaacaagaa ctttctctaa aatatatggt cttgcagggc ttagagtagg atatggtatt
    17881 gctaaagatg agataataag aactttattt acagtaaaag agcctttctc tgcaaatcgt
    17941 gttgctataa gtggagcaac agcagcactt gatgatgaag agtttataaa agaaacatat
    18001 gaattaaata gagttggaat ggcttacttt aaagaagagt ttacaaaaat gggatttgat
    18061 gttgtagatt cacaatcaaa tttcctttat gtagatatga aaacagatat acctaagtta
    18121 tttgaagact tgaaaaaaag agggtttgta ataagaccaa gtgctacaca tgcacgtgta
    18181 agtattggaa ctatggaaga aaataagaaa tttgtagcag ttttaaagga aatattaaat
    18241 attaaaggag agccaagtat tggataatag atagaaatat tatgaaacgg ggtgtagata
    18301 tgaacttaaa aataaacgca gagagatgta aaagttgtga atactgcgtt atatcttgta
    18361 aaaaaggagc attaaaaata tcaagtaaga taaacaaaga aggttatgct catgtagaag
    18421 ttgatgagag taaatgcata ctttgtggaa tttgctatca ggtgtgtcca gataatgttt
    18481 ttgaaataat taaagaagaa gcatgtcaag aggcttagaa ggagttggga taatatgaaa
    18541 aagatgtgga aggggaacca cgccattgca gaagcagccc taagaggagg ttgtgaattt
    18601 tatgcaggat atccaattac accacaaaca gaggtaatgg aatttttatc acatagaatg
    18661 tctgaacttg gaagaacttt tatacagtcc gaaaatgaga tggctgctat atatatggta
    18721 tatggagcat atgcaagtgg aatgaggtct atgacgagtt cttcaggacc aggaatatct
    18781 ttaaaacaag aagggatttc ttacttatgt gcaaatcatt acccttgtgt aatcgtaaat
    18841 gtacagagat gggggcctgg tcttggctca ttggactcag cacagacaga ctatctaaga
    18901 gatactagag ggggaggaaa tggagattat catttgatag tttatgcacc aaacagtatt
    18961 caagagactg tagatttgat gtataactca tttgatgtag cggagaagta cagagtgcct
    19021 gtcgaaattt tgacagaagc agctttaggt caaatgatgg aaccagtaga atttccagag
    19081 tttaagaaga gagaaggaga tttaggctgg acttatgatg gaagtaatag agaccatgca
    19141 aaggttgcag ataaccaaaa gccaactttt tgtatggaga aacgtatgag aataactgaa
    19201 aatgaacaac aatgggaaga ttatcaagta gaagatgcag aatatgtgtt tgtagcgttc
    19261 ggtataccat caagaacaac tatgaatgct gttagaagac ttagagaaca aggtgaaaaa
    19321 gttggaataa taagaccaat aacagtatgg cctttcccat ataaagcatt tgaaaaggta
    19381 agtaaagatg taaaaggatt tatctcagta gaatcaacag acacaggtca attagtagaa
    19441 gatgttgctt taacctcaaa gaaagtatgt aaagaaaatg tacctgtgta tggtttattt
    19501 agtggaaatc atataccaaa aacattgcaa gtaatggaca cttatagcaa aataaaatct
    19561 ggcgaaatca aggaggtgtt ctaatatggc tacagaaaaa ttaacaccta gcgttgtttc
    19621 aataccaaac aagttttgcc caggttgtgg tcatggaata gtaaatcgta taatagcaga
    19681 ggtaatagaa gaacatggat atgaaaaaaa tcatgtatta acattaggag ttggttgtgt
    19741 ctgcaatatg aattttagct ggaatggtga taagatgcaa actgcacatg gtagagcttc
    19801 atctacagct ataggagtta aagtagcact tccagataca ttagtaatga cttaccaagg
    19861 tgatggagat gcttatgtta taggtctttc tgaaacttta aatacagcat atagaaatca
    19921 taatgtgact gtatttgtaa taaacaataa taattttgca atgactggtg gacaaatgtc
    19981 atggaccact atgccgggtc aagtcacaac aacaagtgta aatggaagag atataaagac
    20041 tactggtagt ccactgaaag ttcctgagat ggtggcaaac ttctttgatg tagcatatgt
    20101 agcaagaggt tcagttcata gcccaaagga aataattaat ctaaaaaaat atataaaaaa
    20161 tgcaatagaa gctcaattaa atggagaggg atattcctta gttgaaatat tagcaccttg
    20221 tccaactaac tggggtgtat cactagagaa atctatcaaa tggatggaag aagaaatagt
    20281 gccatattat gctcttggcg aatttaagca aagggatggt gaatagttat ggaaaaagag
    20341 ctagtatttg cagggtttgg tggtcaagga gttttaactc ttggtctgat tgtagctgag
    20401 tcagcacttg aattggggaa acaagtaact tggatgcctg catatggtcc aactatgaga
    20461 ggtggaaaag cctatagtgt agtaaagttt tctgatgaga gtataggtgg gcctgatatg
    20521 gaagaaatag atgttttagt agcaatgaat aaaccatctt tagattatat aaatttagtt
    20581 aaagaaggtg gaacagtagt tattaataca tctgcaatag atgagaatgt aacattaaga
    20641 gaagatataa gtgtagttaa aataaattgt caggaattag ctcaaaaagt aaacaatcca
    20701 aaagcagcaa atatagtagt acttggagca ttaattgcta aaacagggtt atttgaaaaa
    20761 gaattagctt taaaaactat gtgtgatttc tttgaggaaa aaggaaaagg aaagtttaat
    20821 gttcaaaatg aagcagcatt catggaaggc tataataacg ccatttgata aattaccctt
    20881 atcttaagtg atttatctca agatttaata atctttagtg ccaagagaaa cttcatcttg
    20941 agataaaatt cacttaaaat cacaactata aacatatagg agcgtgaatt tatgagtttg
    21001 gaaaaactta ttagaccaaa aagtattgct atagtaggag tgactgataa acttggtttt
    21061 ggaagaagtg cagcacttag tatagtaaaa agtaaggaaa cagatagagt atattatgtt
    21121 aatcccaaaa gagaagaatt gtttgggaga aaatgttata agacgataca agaagttcca
    21181 gaagtagtag actgtgtagt agtatgtaca cctagaaatg tagttccatc tgtattaaaa
    21241 gattctggag agttaggaac aaaggcagca gtggtatatg ctagtggatt tgcagaggaa
    21301 ggtacagagg aaggtacaga tttagaaaat caacttatag aaatatcaaa tacatacgat
    21361 atgaaaatat tgggtccaaa ctgcatgggg ttgctaaatt gtatagataa ggttaatcta
    21421 tgggcaggag gttctaaatg ggatttagat actaaaaaac ctggtatagg aattgtaggt
    21481 caaagtggat ttataactgc tgaaattgtt tcaagtgatt attttaatat atcttatggt
    21541 ttttcaacag gaaatggaaa tatagttaca ctagaagatg cagtagattt ccttgtagat
    21601 gatgattatg catcagtaat agcaatttac cttgaaggtt taaaaaatcc tcaaaaattt
    21661 atagatgctt taaaaagggc agcacaaaaa agaaagccag taataatatt gaaatcagga
    21721 aggtcagaaa aaggtgctat ttctgctgct tctcatacag gaaatttagc tggttcgagt
    21781 aaagcttttg aaagtatttt tgaaaaatat ggagtaattt ctgtggaaaa tttagaacag
    21841 tttatgtgtt tagcacaagc ttttagtgtt ttagatggta atttacctgc aaattctaat
    21901 tttgcagcaa taaacttctc aggaggagaa aatactattt gtgcagattt agcagaagaa
    21961 aatggtgtag aacttgcaga aatatcttct gaaactaaag aagaaatgaa aaaatatctt
    22021 ccaggatttg caacacctaa aaatccacta gatgctacaa cagcattatt ccatgaaaag
    22081 gatatgatag taggtttatt acataccttt gaaaaggatg atagtgttgg atttactatg
    22141 gtaggtgcaa atataagaga tgaagaaaat gaaatgcatg aaaccctttg taaagctgta
    22201 agtgaagcta gagaacaagg attgaaaaaa cctgtgtttg cagttcctac acttgaagga
    22261 aatagatatt tagattatag gactagatta gaagataatc aagtgcctat aatgtcatca
    22321 gttggaacta catttacttg ttttaataaa atggctaagt ttatagatta tgattattca
    22381 aaaagaactt tagaatttaa agctgttaag aaaagagagt caaataatgt agtagcatta
    22441 tcagaattag atagtaagat tgagatgaaa aaatatggag taccagttcc aggacaaggt
    22501 aatgcaaaaa gtattgatga attagatgaa atcttaaaat atattaagta tcctgttgtt
    22561 ttaaaaataa attcttctga aatattgcac aaatctgatg ttggaggagt taaaatagga
    22621 attgagaata gagatgaggc agtagatgca tataatgaga ttttaactaa tgtaaaaaaa
    22681 gcaaaaccag atgctaatat tgatggtata ttagttcaag aaatggtaga aagtggtata
    22741 gaaattatta ttggtataac taatgatgac caatttggac caatgttatt agtcggttta
    22801 ggaggagtat ttgtagaggt atttaaagat actacattat atccattacc tataaatcat
    22861 gatgaagcta ttatgatgct taaaaaacta aaatcattta agcttttaaa tggctataga
    22921 ggaagtgagc cttgtgatat tgatgctctt gcagatatga tggtcaagtt aggaaaatat
    22981 gcttatgaaa ataaggatga agtcaaggaa atagacttaa atccagtgtt tgtatatcct
    23041 aaaggaaaag gcgtatgtgc agtagatgcc ttaatagtta aatataaata gtttataagt
    23101 tttggtattc aaccataatt aaagcaccga ctgaaaatca cattttgtaa gttagatagt
    23161 gtgattttca gtcaccccaa atttaattta aaaatatttt aaaatgaaag tatagtttta
    23221 agtttaattg tgaaatagca ctgtataaac aataaaatac tacgtataaa acgaataata
    23281 aaaggtgttt taatgataag aatcaatctt gattttcatt aaaacacctt ctttattata
    23341 ttaaaaattt ttaaacgtta tattgtcaca ggtgggtttg ttggagctgc atatgtacga
    23401 ttagcaaatt cttggtcaac aaagaataga ccaccctctc cagcaagttt aacacgtttt
    23461 atattgtctt cacaatttgt ttcttcttct gcttgttcag atataaacca aagtaagaat
    23521 tgagaagttc taaagtctga ttcagagttt gctacagctg ctaagttgtt tattaaagct
    23581 gtaacctttt tttcatgagc taacgtacgc tcaagaatat ccattgcaga agtaaagtct
    23641 gaatctggca ttgggatagc atcaagctga acctttcctc ctacattatg taagtatttg
    23701 taaaaaaaca tagcgtggtc tgtctcttct ttatattgaa cataaaacca attagaaaat
    23761 cctttaagtc cttctgcttc aaggtaagaa gacatagaaa gataaagata cgcagaatat
    23821 aattcatggt taatctgctc attaagtaat ttttccattt tagctgaaat catttttata
    23881 cctccaaatt ttaaatgctc ttataaaata taataatatt aaatggaaaa atattcaata
    23941 aaagtgttta aatattttac atatttaata aaaatttata ctaccattaa aaaaattata
    24001 acttacaatg gctatagagc caattaatgg tgcatttgct ccaaaatttg aatgccttac
    24061 acttattttt ttatatttag aaaaacttgc tgaagcagtc aattttttta ataatgtatt
    24121 ttctataaat gtaccaggta tattaaagtc atagcctatt attatagaac tacaatcaat
    24181 caatgtaagt gtattaacta atgcatatga tacgtatgta caaaattcat caagcaaaaa
    24241 catggcaaga ctatctttat tatttgcctc atctattaac ttgactaaag aaaaatcttt
    24301 acagttaatt aatggggagt taggataaat atggctcaat gattcaattc ttttaattag
    24361 attactgaca cttgtataat aatctaaaca tccattatta ccacaactgc acaatggtcc
    24421 actaaaatta attgatgtat gtcctatttc tccactttgt cctaggttgc cagtatgaag
    24481 tttattttct agaactagac cagctccaat accattcatt atgtgtaggt atatataatt
    24541 tgatatattt ttacctaaac catacatttt ttctgctaat gcacccgaat tagcatcatt
    24601 tatcaaaaat attggcaaat cagacatttc ttttataaaa tctactatat ttaggtttga
    24661 tacatttcca aaatctgggg gatttagtat ggtaccattt atatcatcta ctggacctat
    24721 tgaagaaata ccaattccaa ttatatctct cttgttgatt ttcattattt tagtaaacat
    24781 tctttttatt atatctttta aaacatcatt tgatagacat ttggggtaag tttcagaaag
    24841 ttgttttaca atattacctt ttaaatctga aataattacc ttacatatat ttcttcttat
    24901 taggattcca caaatacaag gcgatatatt agaaatatct aataaaatag gtttacgacc
    24961 tgatgaatgt gcatttaaag ttgatgactc tatttcccta atcatatttt cattaataag
    25021 ttcagtaact agatttgata aagtcatttt agtaagtcct gtagacttag ctaaatcaac
    25081 tctggacata ggtgtatttg tagaaagtaa tttcaatatt attaacttat ttttaatttt
    25141 tacatctttg atgttagaac cttgtttgtt actcatcata aatctcctta aataaagtta
    25201 agtgttttat ttattttcaa gtatactatc accttataat agagtaacat ttttttactt
    25261 gaaaatatca ttaattagaa tatatcacat tatatatcat aaaatatata aaaaaatgtt
    25321 agaattaaat taaaagtgaa aagtagattg atatataaat agtaaatact taattaaaaa
    25381 aagataatga tagcaataat tattgttacc aagaatctac tacttcaagt gttaccttag
    25441 gtatttaagt tgatagtggt ttgcacgtaa taaacttgat gtaatatata ttcttaataa
    25501 tatcgataaa agatttactt aaaaataata tagattatgt aaacatataa tctatttatt
    25561 gtatacaata aaatttcatt ttgtaaaaca gtgaattaaa tatgtaatat agatatcgat
    25621 ttttattaca aattgttact aaatataggt acattagaac aaaaatctag taaattgtaa
    25681 ctaaaatgta aatttttcct ttaatctata caatattatg gaaacttttt gtaatttatg
    25741 atataataac aaatatataa ttattaaatt ataataaatg actatagcgt agatgtaata
    25801 ctatgttata gtcatttttg aattaaactt gatatatcaa gggggaagaa tatgagaaca
    25861 attagaagag ttttagcatt aggtttaaca ttagctatat ttctaataaa tgtacctaat
    25921 gtagatgcat taacatcaga tacaattaaa ggtaacaata tatatgagac ggctggatta
    25981 atagcagata aaaagagtta tgatacagca attatggtaa atatggataa ttctatagca
    26041 gatggtcttt cagcaagtgg tcttgcaggt gctgttgatg ctccaatttt gcttgcacaa
    26101 aaaaataaga taccaaatga aacaaaacaa agattaaaaa atgttaaaaa gatatacata
    26161 ataggtaaag aattatcaat aagtaagtca gtagaaactg aactaaaaaa cacaggggca
    26221 caggtaacta gattgggtgg agatgacaga ataaagacta gttatagtgt tgctaaagag
    26281 gtaaatggta tcaaaaaagt tgatgaagtg atattaacta atgcatataa aggagaagca
    26341 gatacaataa gtgctgcacc tgtatcagta agagatatag ctcctatagt acttacagat
    26401 ggaaagagtg tacctttttc aacaagcaat gtaaaaacat atgcagtagg tgggagtata
    26461 tcaatgagca ctagtttagt taataaaact aatgctaaaa gacttggtgg ttcagataga
    26521 tatgatacaa ataagaaagt tataaaagag ttttatccag atgcatcaga attttatttg
    26581 agtgatggat atgatttagt aaatgcactt acaggttcta caattgctaa ggaaaatcca
    26641 attgtattgg tgtcagaaag tagtgataag tctatattag caggagcaga taagattact
    26701 agattaggtt caataagtga cagtgtgtat aataagtgtg tttctgctgc acaaaataat
    26761 ggcgattcgt ctacaaaagg tgagtcacct atgaaaaatg agacaagcat attaggtcag
    26821 ccaacagcta gtttagaagc gtgcttaaaa tgggcaaaat ctaaaaaagc taatgattta
    26881 tttatagagt taataccaat attatatgat actgctgttc aggaaggtgt taatcctgtt
    26941 ttggcagtag ctcaatctgc aaaagaaact ggtttttgta attttggtgg agtattagat
    27001 gcatcattta agaatccttg tggacttaaa acttctgtag gaggttctga tactgataag
    27061 aatgcccatt caagatttga tacttgggaa gaaggaatat tagctcaaat tcaacattta
    27121 tgcttatatg caggacaaga tggttaccca ctttcaaatc cagtagaccc tagacatgaa
    27181 aaatctttat ttggtaaggc taaaacagtt gaaagtttat ctaataattg ggctggaggt
    27241 caatatggac aagatttagt aagaatgatg ggagaaattg aggcaacaaa ataattgaag
    27301 attatcaaat atccaataaa taaggattga ttattatgaa aaagagtaat atttttagta
    27361 tcatatttcc tacagtcata atggtgctaa tgtttttaac ttttgctaca gatatattta
    27421 atattccaga tattcaatct aaaagtattt ttgttgtggg aatggttttg atttttccaa
    27481 tttctttttt gatacaaggg ataatttgtg tattaaataa gactaattgg attttatctc
    27541 ttattgtgtc tttagtaact tatatagtat taatgtatat atttttaaat gattctgcat
    27601 atatatatgt tttactttat acagcttttt atatgattgg acatataaca gctaaactct
    27661 attacaaaat taagactttt aaaaattaaa ttgaagtata taaaagtaac attaggagaa
    27721 gtatccttaa tgattttcta aaatcagaaa taggtgcttc tcttttttgt aaaaataaaa
    27781 gtatgtaaat aaaatttaac cattataatt ttcttttaac aaatgtatac aataaacttg
    27841 ttgtataatt aagatagata aaataaaggg agggataata tgaatttaat agataatcat
    27901 attcatacta atttttcaag tgatggaaag gattccatgg aagatacaat aaaaaaagct
    27961 ataagtattg gtgttagata tttgactttt acagaccatt tagaacatga tgaagataga
    28021 ggattttgca taaattataa tgactatgtt ccagtattta ataagtttaa agaaaaatat
    28081 aaaaaggaca tagagttatt actaggtgtt gaagtgggtt acagaaaaca tctaaaaaat
    28141 gaaatagaag aaataataaa ttctaatcct tttgattttg tattgtgctc aactcataca
    28201 attgacaatg tacctgttcc atcaaaggag tattttaaag gtcttagcaa agaagatgcg
    28261 tattataaat attttaatag catacttgaa actaatcgtg aatttggaga ttacaatata
    28321 tatggtcatt tggattatat atctaggtat ggaatatatt cagataatag agttatatac
    28381 aatgacttta aagatgttat tgatgaggtc ttaaagtcaa taatcaataa tgggagtggt
    28441 atagagctaa atacttctgg ttatagatat ggattaaatg ctatacatcc aaatgaagat
    28501 attctaaaaa gatataaaga acttggagga tttatagtta ctgtaggttc tgattctcat
    28561 agggtagaag atatatgtaa agattttgat gtggcctatg atatgcttaa gtatcttgac
    28621 tttaaatatg tatctttatt taaagaaaga gaaacttatt ttgtaaatat agaaaaagtt
    28681 aaatctaaca atatagctta gagtgtgttt tgaagtaaat taatggatag ttaaaaagtt
    28741 aatagttata atattgtatc ctctagaaaa atactagagg tttttatttt gctaaaataa
    28801 ctaaatagaa ttaaatttaa atagtatagt ttattttaaa ttgaatagtt tattgttgat
    28861 atattttact attatatatt tttattgtga tataatagta aaatatatta acctatcttt
    28921 agattatata aattattata aaggagggaa attttaaaat gtctaataaa aataaagaaa
    28981 atataacttt aagtaatcaa atcaaaggaa caattcaaaa tagtttaaca aaagaagcta
    29041 tattacatat accaatgagc aattatgcct atggttatga tagagaaaca ctacatataa
    29101 gacttagaac taaaaaaaat gaagcgaaaa gagtaatttt acgaatagga gaccaatatg
    29161 tgtgggataa aggaggtgca ggaggaggaa atttaaatgc atctggagtt ggttggtctg
    29221 gtggaacaaa tatagtaatg agtaaagaag tagaaactga attatttgac tattggatag
    29281 ctaagtgtaa gcctttaaat aaacgctcac gatatggctt tataatagaa ggtcaagagg
    29341 aaaaactttt atttacagaa aaaagaataa tagagttggg aaatgaaaat gatgaaaagg
    29401 aattatgtga aataggtaat ttttttggat atccatattt aaattatata gatataccta
    29461 aagtgccaaa ttgggtgaaa gatactgttt ggtatcagat atttccagat agatttgcaa
    29521 atggtgaccc gtctataaac ccagaaggag tagataaatg gggagctatt ccaaccagag
    29581 ataattttac aggtggagat ttacaaggtg tgatagaaca cttagattat ttgagtgatt
    29641 tgggaataaa cggaatttac ttttgcccta ttacaattgg aaaaaccaat catagatatg
    29701 atacggtaga ttatatggag gtagacccta cattaggaga taaagagact ttaaaaaaac
    29761 taatagaaga agcgcataag agaaatataa aaataatgtt ggatgctgtt tttaatcata
    29821 taggatatta ttctaaacag tggcaagatg tagttcaaaa taaggaaaat tctcgatata
    29881 aaaactggtt ttatataaaa gatatgagta aaattgatac tccaatagaa caaatagatg
    29941 aaaaaaatat accttatgaa acctttgggt gtgaaaaata tatgcctaaa cttaatacag
    30001 aaaattcaga agtaataaaa tatttattgg atgtaggcaa gtactggata caggaatttg
    30061 atatagatgc gtggagatta gatgtttcaa atgaagtaga ccatgttttt tggagaaagt
    30121 ttagagaaga agtcaaaaaa gtaaaaccag acatttatat attgggagaa atttggcatg
    30181 gtagtttacc atggctaatg ggtgaccaat ttgattcagt tatgaattac ttgatgtcag
    30241 aagccatgaa aaaattcttt tgtacagatg agataaacgc cgaagaattt aagtatatga
    30301 taaatgatgt aatggtaagt tatccaatac aagttagtga agttattttt aatttacttg
    30361 gaagtcacga tactacaaga atattgactt atgctaatgg aaatattgat agatttaaac
    30421 ttgcatatat gtttatgttt gtacaaacag gatgtccttg tatatactat ggtgatgaaa
    30481 tcggaatgga aggagaatta agttcaatat ctgaaggtca aagaaaatgt atggaatgga
    30541 atgaagaaaa atggaataag gatatatttg attttatgaa gaagattatt agacttcgta
    30601 aagaaaataa agaacttagg tctatatcaa atgaatgggt gttagcagat aaggaaaatg
    30661 gaacgattat attgaaaaaa gaatctattt ctataataat aaataattca tctaaaaata
    30721 taattttgac gttaccagat tatttagcaa ataaaaaagt aaaagattta tatgaagaag
    30781 aaatagttga tttaaaagaa gaactaatgt tagagaaata caagttcatt attttaaaat
    30841 aatacaaaaa agtatttatt ttagatttca tgttaaatta ttatacagtt taaataagtc
    30901 tttataaacg ataaaaaaat atggtctaca agtgagtgaa ttgaaagtag attttaaatt
    30961 aaagactgag ttagagtaga taattttata aataatatct taaatacaag atagaaaata
    31021 aattgattat tagtctaaaa atttcttgta gaaagaggaa ataagaatga ttgaagcatt
    31081 tatatttgat ttagatggtg taattacaga tactgcatat tatcactata tggcttggag
    31141 aaaactagcc cataaagttg ggatagatat agacacaaaa tttaatgaat ctttaaaagg
    31201 cataagtaga atggagtcat tggacaggat attagaattt ggaaataaga aatattcatt
    31261 ttcagaagaa gaaaaagtga gaatggctga agaaaaaaat aattactatg tatcattgat
    31321 agatgagata acttcaaatg atattttgcc aggtatagaa agcttgttaa ttgatgtaaa
    31381 atctaataat ataaagatag gtctatcttc tgcaagtaag aatgcaataa atgtattaaa
    31441 tcatttgggt ataagtgaca aatttgattt tatagctgat gcaggaaaat gtaaaaacaa
    31501 taaaccacat ccagagatat ttcttatgtc agcgaaaggg cttaatgtaa atccacaaaa
    31561 ttgtataggg atagaggatg caagtgcagg tatagacgct ataaactcag ctaatatgtt
    31621 ttctgttggt gttggaaatt atgaaaactt aaaaaaagca aatttagttg tagattcaac
    31681 aaatcaatta aagtttgaat atatacaaga aaagtataat gagtatatag ttaggagaat
    31741 tatatgaaat gtttatttag taatgtagat gagtggaaga ttatacaaga taagattgaa
    31801 atcaaagaaa atagattagc agagtccata atgagtatag gcaatggata tatgggtatg
    31861 agaggaaact atgaggaaaa ttatagtgga gatacacaca aggggtctta tatagctgga
    31921 gtatggtttc cagataaaac tcgtgttggt tggtggaaaa atgggtatcc agaatacttt
    31981 ggtaaaattc ctaattcagt caactatata ggtgtaagaa ttttcataga tgatgtagaa
    32041 ttagatttag caaaatgtaa agtagaagat ttttatagag aattagatat gaaaaatggt
    32101 attttaaatc gtaggtttat tgtaaatata aatgataaaa aatttgaagt tagggttgct
    32161 aggtttttaa gtatatctgt taaggaactt gcagtaatta aatacagtat aaaatcatta
    32221 aattctaata ctaaaataaa atttgtacca tatttagatt caaatataaa aaatgaagat
    32281 tcaaactatg aggaaaagtt ttggaatgga atttcttcaa gttctttaga atataaaggt
    32341 agtattcttt ctcgaacaaa ggagaatgca tttaatacac cagtattcac tgtgggttca
    32401 atgatgtata ttaagacaaa tggtgatgta gaagctgtat ctcatgagag tgattataat
    32461 tactgtgaaa attcgataac aatggatgtt ttaaaaaatg aggttgcaag tatagaaaaa
    32521 tatgtatcta taacttcaac tagagattat aaggaaagtg agctattaag aaaatgtgaa
    32581 gacattttaa atagagaact atctaaaagt tatgatgata tattaaatga acatacaaag
    32641 ttatggaata aaagatggga aagtgcagat gtaaaaataa atggagataa aagtagccaa
    32701 caaggtataa gatataattt attccaacta ttttcaacat attatggaga agattcgcga
    32761 ttaaatatag gtccaaaagg atttactggt gaaaagtatg gaggagctac ttattgggat
    32821 acagaagcgt tttgtgttcc agtatatcta ggtgtagcag ataaggaggt aactagaaat
    32881 cttttagaat ataggtacaa tcagttagaa caggcaaagg ataatgcaaa aaaactaggg
    32941 cttaaaggtg ctttatatcc aatggtaaca tttgatggag tagaatgtca taatgaatgg
    33001 gagataacat ttgaggaaat ccaccgaaat ggaagtatag tatatgcaat atataactat
    33061 acaaattata caggtgacta taaatatata aaagaaaaag gaatagatgt aataatagaa
    33121 atagctagat tttgggcaag tagagttcat ttgtctacaa aaaaagattt gtatatgata
    33181 catggagtaa caggtccaaa cgagtatgaa aacaatatca ataataattg gtatactaat
    33241 tatatagcta aatggtgttt agattatgct gtagaaaata tcttacgatt agagaaagag
    33301 tgtaatgaat gtattgacag aaataatgtg actagggaag aagttgagtt ttggaaaata
    33361 atatcaaata aaatgtatct gccgtatgat gaggaactac aaataataat tcaaaatgat
    33421 aattttttag ataaagaatt tgtagaagta aaggatttac caaaagaaaa ttttcctctt
    33481 aatcaaaatt ggtcttggga taagattctt aggtcgtgtt ttataaaaca agcagatgta
    33541 ttacagggaa tttactattt tggaaataga tttactaaag aagaaaaaaa gagaaatttt
    33601 gacttctatg aaaaatatac tgtacatgaa tcttctttat cttctagtat ttattctatt
    33661 attgcctcag aaatagataa cctagaaaag gcttatgaat tatattcaag aacagctagg
    33721 cttgatttag ataattacaa taatgataca aatgatggac tgcacataac ttcaatgtct
    33781 ggttcatggc tttccattgt acatggattt gcaggcatga gaacatggaa tgaaactcta
    33841 tcttttgacc ctaagttgcc aaaagagtgg aaaaattatt ctttcaatat aaattataga
    33901 gataatatta ttaatgtaga tgtatgtagt gatttaatta aaatagaaaa tttaaaaggt
    33961 agaccaataa aaattattgt atatgggaaa aaatatatat tagaaaaatg tataaaaatt
    34021 gataaataga tttaataata tttttattat ataaatagtt aaaataagct atctaattat
    34081 ttatttattt taactatttt gtgtgataga aaactatata ttataacaat agtagtgctt
    34141 ttaattaaat atatttcata aatcttcata aaatcttcaa aatttcgtaa agaatatgtc
    34201 acaaaagtaa ggtatattat attcagcaga tagtataagg gaggacaata tttatgaaga
    34261 ataaaaaatt cattgttata atactgataa tatcaatttt aataggtgta ttagtgaagg
    34321 aatattcatc tagagagata aaaaaggatg atataaatgt cagtaagtat ataaaatatg
    34381 ctgatttagc aagtaaaaat aatgcacaag ttaactggaa gtatgtagct tccattgttg
    34441 ctgtgttaaa taaaaataac ttaaaaaacg ttaaggattc acagatacaa gaagtatcag
    34501 atttatttgt taagaatttt tctaaaaata ataaaataaa taagttaagt gatattttgg
    34561 atgagttaga atttagtaat agacaaaaaa gattggttga taattatata gacaatctta
    34621 aggattatgg tataaaacca gaaagattga agtctgatac aaaatatatg aagtttattg
    34681 atgaaattaa aacagaagca atacaaaatt ataaggatta taaaatactt ccatctataa
    34741 ctattgcaca agctataata gaatctagct ggggcaagtc aactttggca aaacaatata
    34801 gcaatctatt tggtataaag gctgacgctt attggaaagg taagtcagtg actttagaaa
    34861 cgaaagaaca tttagataca attatagatg ataaatttag aatatatgat gataaaaatg
    34921 aatctataaa agaccatgca aaatttttag ccacaaataa aaggtataaa aacaatggtg
    34981 tatttgatgc aaaaacgtat atatatcaag ctaaagcatt agaaaaggca ggttatagta
    35041 ctgcgaagga tgaaaatggc aatagtatat atgcagctcg tctaatagaa ttaattcaac
    35101 agtataatct tcaattaata gacagtgaaa ttcaaagtga aatgtaactt tgattaaatt
    35161 tttattgata aggctatgat ttttaaaatc atagccttat tttgacatgc ttttacttgt
    35221 aattattaaa tcgatatcat tatctttcaa aatttacttt atactgtaaa tcaaattatt
    35281 taagttaaaa cttggaatta tttataaaag gattatttac tttatctaaa ttctgcactt
    35341 aaagaacatc ttttccctta agactgaccg ttagtctata aaaattataa ttacttataa
    35401 aaaagtgaat atatatataa agttttcaga aagactttta cttgtaaatt gaaat
//
LOCUS       DAGQVA010000041        35396 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.041, whole genome shotgun sequence.
ACCESSION   DAGQVA010000041 DAGQVA010000000
VERSION     DAGQVA010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.041"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(123..599)
                     /locus_tag="MIV85_002139"
     CDS             complement(123..599)
                     /locus_tag="MIV85_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961473.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(798..2423)
                     /locus_tag="MIV85_002140"
     CDS             complement(798..2423)
                     /locus_tag="MIV85_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2961474.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(2761..3780)
                     /locus_tag="MIV85_002141"
     CDS             complement(2761..3780)
                     /locus_tag="MIV85_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBY2961475.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(3777..4346)
                     /gene="mocA"
                     /locus_tag="MIV85_002142"
     CDS             complement(3777..4346)
                     /gene="mocA"
                     /locus_tag="MIV85_002142"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBY2961476.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(4453..5175)
                     /gene="yqeC"
                     /locus_tag="MIV85_002143"
     CDS             complement(4453..5175)
                     /gene="yqeC"
                     /locus_tag="MIV85_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBY2961477.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSLINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(5358..6635)
                     /locus_tag="MIV85_002144"
     CDS             complement(5358..6635)
                     /locus_tag="MIV85_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBY2961478.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(6774..9080)
                     /locus_tag="MIV85_002145"
     CDS             complement(6774..9080)
                     /locus_tag="MIV85_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBY2961479.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(9073..9867)
                     /locus_tag="MIV85_002146"
     CDS             complement(9073..9867)
                     /locus_tag="MIV85_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBY2961480.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(9974..11332)
                     /locus_tag="MIV85_002147"
     CDS             complement(9974..11332)
                     /locus_tag="MIV85_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBY2961481.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(12677..13768)
                     /locus_tag="MIV85_002148"
     CDS             complement(12677..13768)
                     /locus_tag="MIV85_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961482.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTLMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDMSEVRQEINIMKEDISEVRQ
                     EMTVMKEDMSEVKQEINVLKEDMSEVKQEMTVMKEDMSEVRQEINIMKEDMSEVRQEI
                     NTMKEDMSEVRQEMTVMKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINV
                     MKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIE
                     IKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKED
                     IAEIRRDLNLVELATSKNWSDIVKLKSVK"
     gene            complement(13998..15083)
                     /locus_tag="MIV85_002149"
     CDS             complement(13998..15083)
                     /locus_tag="MIV85_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBY2961483.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFDPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(15119..16432)
                     /locus_tag="MIV85_002150"
     CDS             complement(15119..16432)
                     /locus_tag="MIV85_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBY2961484.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(16433..18724)
                     /locus_tag="MIV85_002151"
     CDS             complement(16433..18724)
                     /locus_tag="MIV85_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBY2961485.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGSDKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEQFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(18714..19508)
                     /locus_tag="MIV85_002152"
     CDS             complement(18714..19508)
                     /locus_tag="MIV85_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBY2961486.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(19547..19993)
                     /locus_tag="MIV85_002153"
     CDS             complement(19547..19993)
                     /locus_tag="MIV85_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBY2961487.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(20065..21471)
                     /locus_tag="MIV85_002154"
     CDS             complement(20065..21471)
                     /locus_tag="MIV85_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2961488.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(21489..22859)
                     /gene="hydA"
                     /locus_tag="MIV85_002155"
     CDS             complement(21489..22859)
                     /gene="hydA"
                     /locus_tag="MIV85_002155"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBY2961489.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLETKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(22992..24179)
                     /locus_tag="MIV85_002156"
     CDS             complement(22992..24179)
                     /locus_tag="MIV85_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBY2961490.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            complement(24306..25520)
                     /gene="dpaL"
                     /locus_tag="MIV85_002157"
     CDS             complement(24306..25520)
                     /gene="dpaL"
                     /locus_tag="MIV85_002157"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBY2961491.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(25883..26554)
                     /locus_tag="MIV85_002158"
     CDS             complement(25883..26554)
                     /locus_tag="MIV85_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2961492.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(26637..28853)
                     /locus_tag="MIV85_002159"
     CDS             complement(26637..28853)
                     /locus_tag="MIV85_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBY2961493.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(28856..29326)
                     /locus_tag="MIV85_002160"
     CDS             complement(28856..29326)
                     /locus_tag="MIV85_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBY2961494.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(29388..30782)
                     /locus_tag="MIV85_002161"
     CDS             complement(29388..30782)
                     /locus_tag="MIV85_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2961495.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(30855..32216)
                     /locus_tag="MIV85_002162"
     CDS             complement(30855..32216)
                     /locus_tag="MIV85_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBY2961496.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(32513..33835)
                     /locus_tag="MIV85_002163"
     CDS             complement(32513..33835)
                     /locus_tag="MIV85_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBY2961497.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(34191..35231)
                     /locus_tag="MIV85_002164"
     CDS             complement(34191..35231)
                     /locus_tag="MIV85_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2961498.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT        10734 a         6961 c         3801 g        13900 t
ORIGIN      
        1 acttaaataa tctgttttat tttaatttat cgcctcagtt attatacttt tttacgaaaa
       61 attatacttt acaataaaaa agatattccc ttatagaaaa tatcttttta aatactatat
      121 tattatatac ttgctaacat tggaatatct aacatcttct tcattacatc atctactttt
      181 tttgctttat attcattgta tccaattaaa tatccttttt catatgaact ttttaaaatc
      241 tctttttcat ataaattatc agatttggct tctgtgacac ttaaattata aagcccttta
      301 cacccatctt cataaccttt attataccct ttttctgcaa aatagttttt atgatttttt
      361 tcgttatgta ctgaagatat tgttactcca gaattttctt ttgtactagc ataaggacaa
      421 aaacctttat tgtgttgatg tgctgaatgt cctccacaat aataacgtgt taactctgat
      481 ttatttttat tatgatgacc tcctgatgaa ttatgccctc ctgagtgagc atatgaaaaa
      541 ttccctacac taatcatagc taaactaatt actacagcta ctaacctttt cttaaccata
      601 atctattccc cccaaaatgt tatatatttt tattatatca tctactatat tatatttaaa
      661 ttcttaatat acaaaatatt actctattct gctaataaac atgtttaaac aacataaaaa
      721 acctcctaat atttgattaa aaatttacac actcatgcat agcatgtctc aaatattaaa
      781 aggttttata ctaataatta tttatctttt ccatacattt tagctaattg gtcttgtatc
      841 tctttacttt ctaaatactc atcaaagtcc atttttctat ccattattcc atttggagtt
      901 atctctataa ttctatttgc tatagtagat ataaattcat ggtcatgaga agtaaataaa
      961 agcactcctg ggaacttttc aagtccttta tttacagaag ttatactttc taggtctaag
     1021 tggttagtag ggtcatctaa tacaagtaca tttgcatttg aaagcattag cttactaagc
     1081 atacatctaa ccttttctcc tccagatata acttgagctt cttttaatgc ttcttcacct
     1141 gagaataaca ttctacctaa aaatcctctt ataaaacttt cacttttttc ttcagagaac
     1201 tgtctaagcc agtcaaccaa agaatattct actccgtcaa aaaacttatt atgatttttt
     1261 ggaagataat cttgagaagt agttactccc catttatact ctccactgtc tggttcaagt
     1321 tctcccataa ctatgttgaa aagtgcagta gtagctattt catctcccat aaatactact
     1381 ttatcatctc tatccaatct aaatgacaca ttatcaagaa ccttaacccc atctatagtt
     1441 ttagttaaat tgtgtacttc taaaacttca ttcccaattt ctcttgcagg tgtaaatcct
     1501 acatatggat atcttcttct tgatggttgt atatcttcaa cttctaattt ctctaactgt
     1561 ttctttcttg atgttgcttg tttagccttt gaagcattag aactaaatct agctataaat
     1621 tcctttaatt gagctatctt ttcttcagtc tttttatttt ggtccttagc caattgtaaa
     1681 gccaattgac ttgactcata ccagaaatca tagtttccaa cgtacatttg tattttacca
     1741 aaatctacgt caactatatt agtacatatt tgatttagga aatgtctatc atgtgatact
     1801 attataacta tagattcttc taaatccatt ataaaattat ttaaccagtt tattgattta
     1861 aaatctaagt ggtttgtagg ttcgtccatt aatagtattt caggcttacc aaaaagtgat
     1921 tgtgctaaca ataccttaac cttttcccca ccaactagtt ccttcatttg tttgtaatgc
     1981 atatctttcg ttatgccaag gcccataagt attttctcag cattagtttc tgcatcccat
     2041 ccgtcaagct ctgcaaactc accttcaagt tcggcagctt ttatcccatc ttcttcatta
     2101 aagtcttcct tcatatacaa tgcatctttt tctttcatta tgttccaaag tctctcatga
     2161 cctcttataa caacatttaa aacagtttct tcttcatatt caaagtggtc ctgttttaaa
     2221 actgacattc tttctttatc agttatagat atactacctg tattaggctc tatttctcct
     2281 gataatattt ttaaaaaagt agattttccc gcaccattag ctcctattat tccatagcaa
     2341 ttacctttag tgaattttaa gttaacatct ttaaatagtt ccttatcacc aaatctaagt
     2401 ccaacacctg taacttgtaa cattaatata ttttcctttc tttttgctca taatttattt
     2461 tatcataaaa ctttgataac atttttatta tatattatca cgtaaatagt atatttttta
     2521 tactaaattt gtgaaatatt tattaaaata atactaaaaa ttgtaaattt ataaaaatta
     2581 acaatctctt atattatact tataaagaaa tcaaattgca actttattca ttcttttaca
     2641 cattgaaaat aagttattat aatttctaaa taaatatgct tttcttaaaa catcattcta
     2701 gctgttttgt ttcatattta aaaagagtac ttaatttgta aatactcttt tttaataact
     2761 ttatatttta gcaaaattac atgcaggata agtacataca tcacagttca tacaaaggcc
     2821 accatgacca tatctagcta tatcatactt atcaagcttt tcatcaatta aaaccctaga
     2881 taaaactata tcaaatactg tagttttgtg atacattgcg catcctggta tacccataat
     2941 tggaacttct ccataataag caagtaaaaa catagctcct ggtaatattg gtgaaccata
     3001 tgtcactaaa tcagctccag tttcttttat agctgttggt gtaacatcat ctgggtctac
     3061 actcatccca ccagtacaac agataagttc tgctccttga cttataaatt cttttattgc
     3121 actctttata atctctttat catctgggca tatagtctgt cctataactt cacaaccaaa
     3181 gccttttact ttttcttcta ttacgggtcc aaatttatca acaattctgc tataaaacac
     3241 ttcatttcct gtagtaacaa ttcctacttt cttaggttta aaaggtacta catttactat
     3301 ttttctatta ccaactactt tttttgcatc ttctaatttt ttctcatcta taaccaaagg
     3361 tatcactctt gttccagcta cttttaaacc tttatttact ataaaattat tatgaagagt
     3421 agccatcatt atttctccaa cacaattcaa atcaaaaagt gcatcaacat ctatctttaa
     3481 tagaccatca catgctgcta taaaatctat tttcccttct tttatttcac taaaatctaa
     3541 attttctcca gcagttagtt cttttaaaaa caatgcgcct tcattttcat gaaccattcc
     3601 ttctgacttt tcccatacat acaaattatc tttaccaaga gataataaca ctggaatatc
     3661 ttcttctttt actatgtggc cttttttaaa ttttcttcct ttaaattctc caggtattat
     3721 ttgagttatg tcgtgacata aaacttgtcc aacagcatct atagttttta ttagcttcat
     3781 aatttacccc caattctctc atagtccatt tttgtatcga tatcaaataa catttcttta
     3841 ggaacttcta catactttat ttttgatgaa ttttttaaaa tggttttacc tttttcatct
     3901 tctttaagtg ccaacaattc ttctttcttg ctatatggga atatgactgg atttccacac
     3961 atatctttgt atcttggaat tactataaaa tctctatcta atttaaaagt atttataatt
     4021 ttatctatat ataagttatc aataaatggc tggtctccta caaagaacat ataaccatca
     4081 cattttgagc tatttaaaac tcctaatttt atagattcac tttgacctat atttgcattt
     4141 ttattatcta tatattcaaa accatattta ttacacaata acaaaacctc ttcatattga
     4201 cttactacta caacttgatg aaaatcaatc ttgctaactt ctctaaatac atgttctatt
     4261 atagaacagc ctttataatt taataaaagt ttatttgctc ccattcttct ggcaaagcct
     4321 gatgccatta tcactgcatt tatcatatat atcatccttg gtatttataa tatattgata
     4381 gttctatgat ttttataata tctctattga tattatctat atatataata tcatataaac
     4441 tattttaata cttcaatatc ttacacaaaa tttttgtttt acacttccat aaaatatctc
     4501 tatttcactt tcatattctt taatattttc tattaatttt atagctaaat ttttatattt
     4561 ttcattttca actttattaa taaataatac tctttttcca gaataatttt taaataatcc
     4621 atttggattt aatactatat tttttaagtt ttcaatactt actgtagaac tactattaat
     4681 actacttgta tctaaatttg ctattttttt aaatatttct actctatgta tattctcttc
     4741 attaatattc attccaaatg atgttatatc taatatccct atggtttttg tagttttatg
     4801 atatactact ggttctttag cattccaacc tttaagtttt tttctctttg agccatctcc
     4861 ctctattaaa actaaatcaa attggtctac aatttcatcc aaaatagagg aatcaatact
     4921 tactaattta ttttcattat ttatataact gccacagact gttattccat gacaaataga
     4981 tggaataaca gttccatcta ttgtaataat tatattgtca taatcgtttg gtacatatat
     5041 tttagttgtt gttgtaagga gaactttcaa tttatctcta taaaaatttg caaaatagtt
     5101 tataagcgaa gtttttcctc ctgctccaac tacagttatt atttcattct tttctattat
     5161 atttgatagt tccacacttt cacctcttat aaccagtttt ctaatctctt aattattata
     5221 gttagacctt tttagtaaaa gtgatttttg aaattccata aactcgaaag taaatagatt
     5281 ctgttgtaaa caacaaggcg gatccaattc gccgctaagc tgtaagctta cgctatcagt
     5341 ttatctttta aatataatta agatattctt actctctgtg gttgctttaa tatttgagga
     5401 ttattctgta aattagataa attaactact tgtgattttt ttagtatatt aagactcgca
     5461 tttacatctg catttataat gattccaaca ctggatttgt actgtccacg cgttattctt
     5521 tcccctttaa agtcatattt tttaacattg tccacattga tatcaggtag aaaatcatca
     5581 gcaaaaaaat ctgatttact agtatagctt tcttcttgcc taataaaatt gatatttttt
     5641 attttacaca gatattctaa ttttcctttt atctctccaa atgggattct tataaaattt
     5701 ctatatattt ttctctccat attatcactt ttttctaact tagcattata tcctacaatt
     5761 aaatttccaa tattattttt tacacaataa tcaattatat aaaaacaggt tttatttaca
     5821 tagtctttaa cttgattatt tctcttattc caaactttaa attgttttct tgttattgca
     5881 gttatattct tttttaattt taaggcttct attttatcat tctgtttgtt tgcccactga
     5941 ttcacagatt ttagcctttt tccatctatg ataaaactat cacctaaatt ggtaacacat
     6001 gtacataaat tttctaaacc caagtctata gctagtgcat ttttttgatt tgaaacttcc
     6061 tctgattttg gtatttcata acaatactga atttcaaaga acctagcttt atgtttaggt
     6121 attattctta tttctttaat ttttttctct agtatatttt gtggaacttt tatacttact
     6181 ttcccatata gttttttaaa tgctggagac ataggtacat ttaaaatccc atcttctttg
     6241 attcttattt gacctattat tatgctaaaa aatccttctt tatctaaata tttaggtgat
     6301 tttatccctc taaagtcata ttttccttct ttggctaatt taattaatcc aaaaaatgac
     6361 ctaaacgaac tgtctacttc ttttaatatt tgttgcgcta tattactatt gagaagctta
     6421 tagttctcat tttctttgca tacatgataa ttagcttcat agttaagatg ttctccttga
     6481 ttgaaataat gctgtcttac attatatgta ccaacattat ataagttctt agctaagaag
     6541 cacatttctc gtagagcttg atattctttt ttagttaagt tttttaattg ttgtctctga
     6601 gttccatagt gtatattttt tattctgttt gacatgaact cacctccttt agaatatact
     6661 ctactagaca ttatatacgg tatttttaca aaacaccata tataatgtcc atttaattac
     6721 tttattttac aaaataattt aaatttactt gcttttatac atcttattat ttattataat
     6781 tgtttattat tatttttcat acccatataa actttttcaa aagtcatagg aagctctctt
     6841 aaacgaactc ctgtagcatt aaatattgca tttgctatag ctggtgctgg tgtatgtata
     6901 actatttctc ctaatgattt agcaccataa ggacctcctg ggtcgaaatt ctcagcaaaa
     6961 tctaccaata tatttccaac ttcttttttt gtaggaactt tatactgtag gaaactatct
     7021 gttaataatc taccatcttt atcaaatata gggtcttcat acattgcaaa ccctataccc
     7081 atcatcacac caccttctac ttgtattcta gctaaagttg gatttataac tgttccacaa
     7141 tcaggtacac atgcaaaatt tatgacttta tattcgcctg tatttttatc taattctatc
     7201 tctgcaaatc ctgctataaa tggttttatt tttttcaaca tgccaaaaga ttctgttgct
     7261 tccaaaacta ctggtacatc atcactagca aatcctattc ctccaacaga ttctctaccc
     7321 aattcctcta atagaacaaa cttgctatta tcgtttttaa caaaaaccct gtcttttccc
     7381 aactctaaat cttctttttt aaatcctagc tttgactctg caactgaaag taatatatct
     7441 tttaatttat ttgctgtctt tattgttgca tttcctgtaa ccgttgtcgt acaagaagca
     7501 aatgctcctg tatcataggg acataagtct gaatcacctg tataaataga aattctatct
     7561 acagtagtat ttaaagcttc cgcagcaatt tgagcttgaa ttgtatcagc cccttgacct
     7621 aagtcagcaa gaccagataa tagtttatat gtgccatctt catccattct tatagtgact
     7681 gttgccatat ctacacgcgg tataccagaa ccatgatttg ctactgccat acctactgct
     7741 cttactttgt tgtttcctat atctttacat ggatatttat catcccaatt aattaatttc
     7801 ttgccctttt ctatacattg tctcagctca caacttaata tttcgtcttc agctgctttt
     7861 ccattggtat acctatctat tatattttta attctaaatt caagtggatc cattccaatc
     7921 ttatgtgcca attcatcaat agcactatct attgcaaata ttccctgtgt agcaccatac
     7981 cctctaagtg ctcctgctgg taacctatta gtatatactg ttctagcatt aaatctaaca
     8041 gcatcaatat cattatatat tggtaaggta ttgtgtccag attcggaaga aacagagaca
     8101 ccattcccac cataagcacc tgtattgttt aatgacttta gctctattgc ttttaaattt
     8161 ccttctttat ctgcaccaac tttaacatca aaaaacattt catgtctact attagaacct
     8221 acaaaagttt cacttcttgt aaatacaaat tttgctggtc taccagtttt catagtaaca
     8281 aatgcagtaa atatatctgt tgctgctata ttctttcctc caaatccacc acctattcta
     8341 ggtttaatta ctcttatttt tgaagatggt atacccaata cttttctaag tattctcttt
     8401 acattgtgtg gtgattgtaa tgatgaaact acaacaattc tatcatttat atctttatat
     8461 gaatatgacc tatgagtttc catcatgcaa tgcgattgac tttgggtttt gtatgaagat
     8521 tcaaccacaa aatcactttc tttaagctta gcttcaacat ctccaaattc aaaaaattct
     8581 tttgatacta tattattttt tgcatccaat ccaaaaggat atggctctac tatgtctttt
     8641 tctggatgta taacaacttc atttccttct gcttctcttg catcaaacac aggctttaaa
     8701 acctcataat ctacctttat catttttaag gctttaagtg ccgttttctc atcttcagca
     8761 gccactaaag ctacttcatc tccaataaat ctaactgtat cttcaagtaa aactctatca
     8821 taaggtgatg cttctggttc tgtttgacct ggcacacaat atctgacctg tggtacatct
     8881 ttatacgtat aaatacccac aacccctgga attttttcgg cttttgatgt atctatattc
     8941 tttatcttag catgagcatg tggacttcta agtagtttta atgtcaaaac atctttatgc
     9001 ataatgaggt cttcagtata tagaggtttt cctgtgacaa ttgctgtact atctatcttt
     9061 cttatcccct tattaatcat tatacattcc ctcctcaata gcattataca tccttttaac
     9121 taatgcactt gccatatcct ttctgtactc tttactagct ctcatattac ttccataagt
     9181 aagttcctta ctagcaacaa tagatgcctt atctatatct ttttctttat ttaatatatt
     9241 actcgcttca agtgctaatc tagctttttg aggtcttgcc ccaattgcta ttttgtaagt
     9301 atcattttct tttagcattg ctgaatttaa tacagaaaaa tctcctgtgc attttcttat
     9361 tgagtcaaaa acagctattg catctttttt tggtagtatt acttcgacca atatatccct
     9421 acttaattca ctatccaaaa actcacttaa ctctagtatt cctttattgt ataatctcac
     9481 cttcgctcca acaaccaaaa gcgctggtat taagtcagaa aagccatact ttgaaaatac
     9541 acttgcacca attctagccc cttgtctaaa ttgaacacca actatattag aaacagcgct
     9601 tgaaagtatt ccactacagt aattttttat agttttatca atttctaaac ttctaagtga
     9661 agtatctgca cctatcaaaa tatttttttt atcctctttt atataattta gatttatatc
     9721 ttttaaatct atcgctgttc ctatattttt attacttaat tttataaatc cacatccacc
     9781 taaaataaca ttattttttt tagaaattaa aattttatat gcttcttcta aactctgtgg
     9841 aactgaatat tcctttatag taaccatctt atccccccat cattaactta ttaaaacaca
     9901 aaagttttta ataaatcttt tatttatatt tataattgta gtatatttaa ttcacatata
     9961 ttaaaccttt acattataaa cttttatttt tatcctcaac cttatcactt ttatttccag
    10021 gaaattttac catatataaa gcttgaatta ttatggctac cattgctcct gaaactacac
    10081 ttgaatctgc aagtaatgtc tctataaatt ttggaaattt ttcaagaact tgaggagcta
    10141 ccatgaatcc aataccagaa gccatagaaa gacctaatat catgctattt tcttgattaa
    10201 atccatccat actaacaagt cttaaaccag atgttgtaag agttgaaaat ataacgagtg
    10261 ttgctcctcc aaccacacag ggaggaattg ttcttattaa attagctaat aaaggcgata
    10321 ttcctgccaa aaataatcca attcctccaa tagctagtac aaatttactt acaacctttg
    10381 tattggaaac gattgcagaa ttttgtccaa acatccccat tggagttgca gaaaataatg
    10441 cacctattgt agagagtact ccatttccta aaacagcaga agaaagttct tcatctgtta
    10501 cttgtctatt aagccctcct accgcagaaa gtgtacaagc acccattata tcagctatct
    10561 caactaaata tattattgaa aacattacaa caacttcaag tcttatatct agcccaaaag
    10621 caagtggttt tggaagtgca accaaagtaa actcctgaat tgaagaaaaa tttactatac
    10681 ccaaaattaa tgataaaatg tatccaaaaa ttatgctaac taatattgat gcatctttaa
    10741 ataatccttt tccatactta tttaatccta atatcataag agatacagat attccaacta
    10801 taaaattaat tggattccca aaagtctcat tgcccatacc cccagctaag ttttttatag
    10861 ctattggaaa aagtccaaga cccatacatg caactattgt tcctgataca gctggagtaa
    10921 atataaatcg tattttttta agaccaaaac caattataat tattactata ccagctatta
    10981 tttgagagcc aaataatact ggtagtccat acttacttgc aacagatacc ccagctccta
    11041 taaacatagc tgtagctccc attataactg gtattcctcc tcctaattta aaacctttaa
    11101 acaaaggtat tggatataat tgtaataaag ttgataatcc tgcaaaaact aatgcggctt
    11161 gaatcaataa tgttgacatc ttatgattaa gtccagctgc atttgcaatc aatatcgctg
    11221 gtaaacaact acctattacc attgccatta agtgttgtaa ccctaaaggt attgcttcct
    11281 ttagtggtgg tattccgtct aattcaaatt ttgatgtact ttttgctttc ataataaaaa
    11341 ctcccgttac ataaaactta ttgaattata taaatactta aaaatctaat atattaaatt
    11401 aatgatgttc ataaatatca actatactcc aacatatatt taagttttta gtcttaaaaa
    11461 acagatgcaa taaatttaat tattaacaaa taaacgtatt ctttaatttt gtatacatta
    11521 tataccatgc tttacaaata taagagtatt atagctatga atttttaatt ttttatagta
    11581 aatttaattc aatttaaatc tttcaatctt aatcattata agttataagt tttcataagt
    11641 atttacatgt ttcaagtttt aaacatttac ctataaacgc tactttatag atgtcacttc
    11701 aaatccagtg acctcatact ttcatatgag cgtagactat ttcttcatct tcagcattac
    11761 ctgctaagag caacccgttt ccactatcaa tcgcttatag tgtactctct ctcgagatag
    11821 tcgtttgacc ttcctatttc taggcttggc gaccaaatgt ccatttttaa gtacttaggc
    11881 tctcaccata taccatcctc actattgttt ctggttttca ccacattcat aaaagtttct
    11941 ttctatcttt tattgtagtt gcaaggcttt aggatttact ggttttaaag ttgtgtccta
    12001 catagatttc tctatgtacg gggccaaaag tacaatttat ttaacatact ttgctttacc
    12061 ccctgtaaat aatattattt actctttcac tgtttttgtt attaaattaa ttaaatatca
    12121 attaatctaa gcataaaata attatttaat ttaaactcaa aatatttatg aatattttat
    12181 aatataattc tcataagaca gaaaaactta ataagctatg tatctcagtt gtaccaatgt
    12241 actctccttt actatatttg tatctgcaac ataaaatata caagtttcta tctatttata
    12301 gatatatatc tataagcaaa atagtaatat tatttttata gtaaaaattt tattcatatt
    12361 actatttata atttttatag agcaatttta gtgccaatat ttgcatacat ttgtatagta
    12421 taaaattttt atgttctcat tgataaaatt ttacttattt caagcgttct attagatttt
    12481 atcatctaaa ttttaggttt tatttttata aattaattgt atttacataa aaaaaaagac
    12541 ctaaaaacaa atttttaacg gtcttttctc aattttttat tttcatttct aaaatttata
    12601 ataaatagta agaacactat aaattctttt atataaaatt cttagtttgt ggatgataaa
    12661 ttagtgaatt aaaatactac tttactgatt ttagtttgac aatatcactc caatttttac
    12721 tagtggctaa ctctactaaa tttaagtctc ttcttatttc agctatatcc tcttttatag
    12781 aattagtgtc accttttata tatgctatgt tatgttctat attatcatga gtagctttat
    12841 ttatttcaga attatgtaat aaacttccta aaatattatt ctgttctatc tgtatctctt
    12901 tcattgattt atcttcacat tctagactat caatcttaat ttcaattcca tataattttt
    12961 catttgctat ggatacctcg tccttaattc cattcatatc ttcattaatg ttatttattt
    13021 tattttgcat aaagtttact tctgatttaa cttcggaaac atcttctttc attacagtta
    13081 tttcttgtct tacttctgac atgtcttttt tcattacatt tatctcttgt tttacctctg
    13141 atgtatcttc tttcattaca gtcatttctt gtcttacttc cgacatatct tctttcatta
    13201 tatttatctc ttgtcttact tccgacatat cttctttcat tacagtcatt tcttgtctta
    13261 cttccgacat atcctctttc attgtattta tctcttgtct tacctcggac atatcctctt
    13321 tcattatatt tatctcttgt cttacctcgg acatatcttc tttcattaca gtcatttcct
    13381 gttttacttc cgacatatct tcttttaata catttatctc ctgttttact tccgacatat
    13441 cttctttcat tacagtcatt tcttgtctta cttcggatat atcctctttc attatattta
    13501 tctcttgtct tacctccgac atatcttctt tcattacagt catttcttgt tttacttccg
    13561 acatatctcc ttttaataca tttatttcct gttttacttc cgacatatct tctttcatta
    13621 aagtcatttc ttgttttact tccgacatat cttcttttaa cacatttatt tcttgtttta
    13681 cttccgacat atcatttttt atgctaacta catcttcatt tatagtatat aataactcta
    13741 aaatcttctc ttgcacttgc atcaccatcc ctattaatta ttataacatt ttacacaaat
    13801 gctatacaat gttaacatat atatcagaat tattaaaatt ttaattaaac aaaattgatt
    13861 cactttatta cttcaaaact aattaatatc taaaataact acaaataaac aaaaataagg
    13921 tcaacaacaa aaaaggctta tctctttgag atagcctttc ttatttttat ttaaaacttt
    13981 gttttttata aaataatcta tacattcagc tctgaacatg aaatttttct tccaagtgct
    14041 tttggtttac aaactgatat acaaagtcca caatatctac actcttcttc attcaattcc
    14101 atcttatcat tcaattttct cgcttgatat gcacaaactc tctcgcacat cttacattta
    14161 gtacattttt cttcatcata agtaaactca aagctaagtc tttcattaac atctcccata
    14221 tgattatgta ctataccaca agcattttct atagtattat atcctaatct attaagatta
    14281 gattttaaat catcatgtat tttagatatt acttgtgcgc cttttaaaat tactactgaa
    14341 catataccaa caaagtcagc acctgccata atcatttcta aggcatcatc tccacttaca
    14401 catccaccta agccaattat tggtatatta acttgttttt ttatttcata tattctctgt
    14461 aaagttattg gcttgatagt ttctccactt aaatatccta ttccatttcc acctaataaa
    14521 ggttgccctg tttctatgtc tattctaaat gctggtccta cagagtcaca agcagttatt
    14581 gcatctgctc ctgcttcttc taatttttta gcaaaatcgc ctatctcatc tatcatagga
    14641 ggaagtttaa ctattacagg tatatttact ctttcctttg catctttaag cattggtatc
    14701 aaatctctat agtcataaga tactaattca ataaagtcag ctcctgcatt tgcaactttc
    14761 tctactaatt cgctactttc ttcaattgta tgacctattg aagctataca gacagtccca
    14821 tctcttttca tttgtggtat ttcaaaatct atccattgct ctggatcaaa atctgtccat
    14881 ttttcattat ttaaaagagc attagctgta tttctaacca tatgtggtgc tggatttata
    14941 gctctttctt ttcttatagt cttagtcaca actgcccctg ctcctgcatc acttaatatc
    15001 ttgcatccag ctgcactata tgttaatggt cctgaaccta ttataagtgg tgattttaat
    15061 tctttaccta aaaaattata cattatctgc ttcccctttt catatatatt tacattcgtt
    15121 aaaatttcca aaattcacaa gcaacttctt tcatttcttt aacaatagct tttttatcta
    15181 aatcaactaa ctgtttttct tttaaaatat gtctaccatc tatgtataca tttgatataa
    15241 attctttttt accctgaact actatctggt caaatatatt atcaagagtc acaggagttt
    15301 taaattcatc ttccataact attatatcag ccttattacc aactgctatt ttaccagaat
    15361 tttgaagtcc taatacataa gcaccatgct ctgttgccat tctaaatact aaatttgctg
    15421 gcattactga tgcatcttct tcaactgatt tatgcattaa aaatgcacct ctcataactt
    15481 caaaaaaatc atttatatat ccatcagtac ccagtgccac ttttatgcct tttttaatca
    15541 tttttggtac tggagaaaaa cctccaccta cttcacagtt gctaagaggc atatgaacca
    15601 cttttacacc tttttctttt aatatatcta tttcttcatc atttactttt acacactgag
    15661 atgctaatac agtttcatcc aatatatcta aatcattata gtagtcaact gcttttttgc
    15721 caaaatgttt ttcagcatag tttggctcat atatactctc acataaatga aattgcattg
    15781 gtgcatttaa tttttttgca tcttctttag ctttcttaat aaatctatca gaacatgtga
    15841 agcttgtatg tgtacacatt attccattta ttaatttact attttctcta ctccacttta
    15901 ttaaattaga attttcatct aaacatctaa gtccattttc aaagcttatt ctttcacaac
    15961 tttctaagga taaaatcgct ttcatgccta tttcttctag tatttttcct tgctcaatta
    16021 aagttccttc ttctgtattt ggagcttcta gggtatcaca aaaagctacc acaccagatt
    16081 ctataagttc tattgctgat gctttagttg ttgccttcac ttctttcaat ccaattctat
    16141 tttctataaa tggccaccaa tagtcattta agaaaccttc aaagtcggta aaatgtacat
    16201 ttgccggtat tcccctagaa agaactccat attgatgcat atgaccattg acgaatcctg
    16261 gcattattat agcatctgat ttatctatta tttcttcaat atttttatat tttatttcaa
    16321 cttcttcatt tggcaatata tcttttataa tgtcattttc tactacaaca gcagaatttg
    16381 tatatatttc atcagcagaa gatattaagt atttactttt aatagcaatc atttatttac
    16441 ctccctgatt taattttttc atggccatat aaactttctc agaagttata ggaagttctc
    16501 ttatacgaac tcctgtggca ttgtatattg catttgctat tgctggtgca ggtgtatgaa
    16561 taactatttc tcctaaagat ttagctccat atggacctgt tggctcataa ttatctacaa
    16621 aatcaacaat tatgtttcct atatcttttt ttgttggaac tttgtattgt aatagattag
    16681 aagtttgaag ctttccatca gaaccatgtc tagggtcttc atacattgca agccctatac
    16741 cttgagttac accaccttca acttgtattc tagcaagtgc aggattcata actgtaccac
    16801 aatctgtaga acaagcataa tttattactt taaactcccc tgttgtttta tctaactcta
    16861 tttcagcaaa tcctgctaag aatggtttag cactctcttg tataccataa gattcagatg
    16921 aatataaaac ttcttgattt ccaccaccaa cagattcttt tcctaattca cttaacaaaa
    16981 caaactgctc tacatcttca ctataacaaa ctctgtcttc atatagtatt aaatcatcta
    17041 ttggtaaatc gagtttcttc tgtgctactt ttaatatctt ttgttttaaa ctttcagcag
    17101 attttattgt agcatttcca gttacataag tagtacaaga agcgtatgca ccagtatcat
    17161 atggacacat atctgtatct cctgtataaa cggaaattct atcaatagat gtattcaatg
    17221 cttttgcagc tatttgtgca agtattgtgt cagaaccagt tcctaagtct gaagacccag
    17281 aaaacaactt ataagttcca tcttcatcca tcctcatatt tactattgcc atgtctatgt
    17341 tggctatacc agaaccatga gttcccacag acattccaac agccctcacc ttattgttgc
    17401 caatatccct aacagggtac ttttcatccc atccaataag ttttttacct ctaattatac
    17461 attcatcaag tgcacaactt cttattggaa aattcattat tccgccttca gtttgttttt
    17521 ttataatatt ctttaacttt atttctgttg ggtccatatt aagtttatgc gctaattcat
    17581 caattgcaca atcaagtgca aatgtacctt gtgttgctcc atatcctctt aatgctcctc
    17641 ctggaactaa attagtatat acagttctcc catcaaattt tattgcaggt acattattat
    17701 atgttggaag tacattatga cctgattcag agcaaactga aggtccatta tcaccataag
    17761 cgcctgtatt attcaatgct ttcatatcta tagcttttat gtttccttct ttatctgacc
    17821 caatttttat atcaaaaaac atctgatgtc tagtattagt cattgcaaaa gtttcttctc
    17881 tagtataaat tagttttgct ggtctttttg tcatccaagt tacaaatgat gcatatatct
    17941 ctgttacagc tatgtttttt ccaccaaaac ctccacctat tcttggtttt attactctca
    18001 cttttgaaag aggtattccc agtgctttag aaacctgtct tctcatatga taagctgatt
    18061 ggtttgcaga agttactact aatctgccat tcgtatctat atacgtataa gctctatgag
    18121 tttccatcat acaatgggct tgtgattgag tcatataaga atgttctact attacatcac
    18181 tttctttaaa ctctttttct acatcccctt tacccatttt ttctctcgat acaatatttt
    18241 ttgtagcatc caatccaaaa tcaaatggac aaaacaaatc atcttcttca tggattaaaa
    18301 ttttatttcc ttccgattct cttgcatcca atataggagt cattacttca tattcaacct
    18361 ttataagttt catagcttta atagcagccc tttcatcttc agcggctatt atagcaactt
    18421 catctcctac atatctaact acgtcttcaa gtattaattg gtcatgaggt gatgcttctg
    18481 gatatgactc tccaaccatt gaatatctat aatttggaac atctttgtaa gtgaatatgt
    18541 ttactacacc ttttaccttt aatgcatttt ttatatctat gttttttatc ttcgcaaaag
    18601 catgtggact tctaagaagc ttaattgtta aaacatcttt atgaaaaatt aaatcttctg
    18661 tatatattgg ttttccagta acaatggctt cactatctat ttttcttacc tctttattta
    18721 ccatcacact cacctccaat actattatac attctcacta ctaaggcttt tgccatatct
    18781 tttctgtatt ctttacttcc tcttatatta cttccaaatg aaagttcttc acttgatact
    18841 tcaccagctt tttctatatc attttctaaa cttaatattt cacttgcttt ataggcaatt
    18901 tttgctcttc ttggtctagc gcctattgca attttataaa tacttccttc ttttaacatt
    18961 gctccattta atactgcaaa atcacctgta cattttctta tagaatcaaa tacacctata
    19021 gcatcttttt taggtaatat aacttctatt aatatatctt tttcaagctc actttctaaa
    19081 aaatcagcta agttcataac ccctttttta tataacttaa cctttgcatc taccactagt
    19141 aatgaaggta ttaaatctga aaatccatac ttagcaaata cgctagctcc tactctagct
    19201 ccacttctaa attgaactcc tactatatta gaaacagcgt ttgaaattac cccattacag
    19261 taatttttaa taaccttatt taattctaaa gttcttaaac ttgtgtctgc tccaattaat
    19321 atgctatcat cagtttcatt tatataatct aaagctaagt cttttaaatc tattgctgag
    19381 ccaatatttt tactacctag ttttaaaaat ccacatcctc caagtattat gttgtttttt
    19441 cttgatatta gcagttcata agcttcatct aaactttttg gaactacata ttcctttata
    19501 gttatcatac tctctcccca tatcaactta attttcactt aaaagtctaa gtgtttaaat
    19561 atttatgtat tgctcttaat tgacctttat atcctgtaca tctacaaagg ttaccattta
    19621 cataatctat aacttcttct tctgttggat tttgaagctc tcttttcatt gccaaaacca
    19681 tcattataaa tccaggagca caaaatccac actggtcagc cccttcgtct gcaagaaaat
    19741 ctccaaactt ctttgcttca tccaagacac cctcaagtgt tgtaatatgc tgaccgtcta
    19801 ctctagcagt aagataatta catgaaagca cggccttgtc atttaccatc actgtacata
    19861 acccacatga gcctgtatca cacccttttt taacacttac atatccattt tctcttaatg
    19921 tatctgctaa aaaatcatct ggtcttatac ttaattcttt ttctttatta tttatggtac
    19981 atttgataat caaataaatc acctcaaaac tcatattttt aagctaaagt tttactatac
    20041 ttttctatga ataaattaca tttattaata aaggctattc catttatgac cttccattct
    20101 attttttata gttcctctta cacaaagtct ctcagctgta tcttgagcat cttttaatgc
    20161 tttctcttca ttagctgtca atatttttga atcttccatt attatatttc catctactat
    20221 aacactctct atatttttca tactagaaga atatactaat gtagataccg gattatgcat
    20281 aggtatcgct tttggtgaaa gcattggatt aaatattagt aagtctgctt ttttacctat
    20341 ctccaatgaa cctatctcat cttccattcc aatagctctt gctccatcta tagttgccaa
    20401 ctcaagaact ttttctgctg acattgctaa tgggtcacac ttattaactt tatgttgaag
    20461 tgctgttaat ttcataagtt caagcatatc ttgagagtta ttactagcgg ctccatctac
    20521 tcctaaacta actgttattc cttttttaag catttctggt actggtgcaa cacctgaaga
    20581 taagtacata ttacttgctg tattatgaga cactttcata tcgtattttt tagtaagttc
    20641 catatctttt tcagttagat acacacaatg taccataagc acatttggtc caagtattcc
    20701 taatttttct aaaacatcta tgtcatattg cccatgcaat tcttttgctg cttctctatc
    20761 aaaaggagtc tctgatatat gtactgtaaa taaagcatca tcatattctt ttactactct
    20821 ccatagcatt tctagcattt cttgagaatt tgaccatatt gctgcaggag ctactcctat
    20881 tttgattctt ccattttctg tattatggtg tttttcaaac aatcttctta catctttttc
    20941 aaccgtttct acatcttgca ttattccagg atgaactcca aattgagctc ctgtattcat
    21001 acatcctctt ccaagtattc ctcttattcc taattcttta taagcatcta ttattccatc
    21061 acaaagacct ggcttactat gaggatacat gtagtcaacc attgttgtta taccacttct
    21121 aagtccttca atacatccaa gcattgcagc atcataagta tcttttggct ctaaatagtt
    21181 agctgctgga aatgtcatag tttctaacca gtctttaagt accatatcat ctcccaatcc
    21241 ttttaataaa gtttggaata aatgattatg tgtatttata aaacctggga ataaaacttt
    21301 acctttagca tctataattt ttttaacatc agtatattta ctttctatct ctttagaatt
    21361 tccaatatca gcaatcttgt tatcttttac tactaatgcc ccatcaaaaa taacttctct
    21421 ctctttattc acagttacta ttatggcatt cttaataagt atatccatca ttcttatttc
    21481 cccccgcatt atttagtaat ttttctttta atatattgac ctgttggatg ttctttaaca
    21541 ttacaacttt gtactacatg atttcctctc aaaaatacat cttcaacttt acatttaacc
    21601 ttaaatcctt catatggagt ataatctaca ttttgttttt gagttttata actaattgtt
    21661 tcttctttat tgatatttaa aatgactata tctgcatcac ttcctacagc tatctcacct
    21721 tttttgggat acattccaaa tatttttgca gcattcgtag aagtaacttc cacaaactta
    21781 tttacactta ttctattttc taagacccca tatgtatata aaagtgctaa cctatgttca
    21841 acaccaggtg ctccatttgg tatcttacta aaatcatcaa ttcccaagtc tttttgcccc
    21901 ttaaaattaa atgaacagtg gtctgtgcca actgtttgaa tatctccact agacaatcct
    21961 tcccaaaggt aatttatgtc ttcttttttt cttaaaggag gagacattac atacttagca
    22021 ccctcaaatt tatccttatt atataaattg tcttctaata atagatactg tgggcatgtt
    22081 tctactatca tatctatgtt tttttctcta gccattttta cagtttcaag tgactcccta
    22141 caacttaagt ggactacata ggattttgaa ttagataatt tagttatatc agcaagtctt
    22201 gaaacagact ctttctcaac tatgttaggt cttgtaagtg gatgatattt tgtctctaaa
    22261 ttaccatttt gtatattttc ttctatcaat acatctagta aatccccatt ttcacaatga
    22321 aatccaacta tacaacctaa atcccttgct ttctttaaaa ccctgtatat tgttccatca
    22381 tctactttca tgccatcata tgccatatac atcttaaaag atactatccc atccgaaata
    22441 agtttttcca tatgattaaa tgtatcttta tttaaacatg taattgtcat atgaaaacca
    22501 taatcacaat aacaatttcc acttgctttt ttatgatatg cttctacacc ttgcagtagg
    22561 ttttccccct cattggcttc tgcaaaatct agtattgtag tagttcctcc agctatagct
    22621 gctcttgttc ctgtttcaaa attatctgca gttgtaatag aacctgcatt catatcaaaa
    22681 tgagtatgtg tgtctattcc accaggaatt acaattttac ctgtagcatc aataacctta
    22741 tcaccattta tttctaagtt atttcctatt tcaactatct tttcatcttc tatccttaaa
    22801 tcacttatat aagtcttatc agaggtaatt atagttccac ctcttagtat tgttcccata
    22861 tatacctcct aacttttaag ctttaaagta ttttctaagt attgtaaaac tttatttaaa
    22921 attgtatttt ctaaaggtgc tatattcagc acctctagac tatatttaaa taatttattg
    22981 tgaactaaat attattttcc gtatacagat tttaatattc catagtaacc ttctgttcct
    23041 ataaataact gttcttgctc tatatactca tctattgtgt gagcaagatt ttccttagaa
    23101 ggaccaaatc ctatagtttt tattccagct tcacctgcat agtgacttcc attcgtacag
    23161 aatgagtatt gagttatttc tgaatctatt ccagcttctt ttaatccctt atatgctgct
    23221 tgaacaaatt catcttcttc gtcatataac caacctggga agaatctttc actttctata
    23281 gtatttcctg tatagcaatc agctttttca accgcataag aaacttttgc atttaattct
    23341 gggtcttctt tcatcatttc atctaataaa gcttgtattg gagctaatac gccttctctt
    23401 gtttctccaa ctaataatct tctatcaaaa gtagctttgc aataatctgg cactactgat
    23461 gctcctggat atggagaaga ttttatatct gttaaaacta atattccatc acctaaaact
    23521 ggatgagttg gaggtactaa ttgttgtatc ttttggatta cattagccat tttataaact
    23581 gcatttacac ctttttctgg attagcagag tgagctggtt taccaaaagt ttctactact
    23641 atttctcctc tacctctctg accaatcttt aagtttaact ctgaagactc acctattaca
    23701 acatagtcag gttgaacagc cttacttatc tctctagccg aaacaccttc aaatatttct
    23761 tcatgaacaa cacctgctac atatagttct ccagcaaaat ctctattagt gtctttagca
    23821 aaatacgcta cagcagacat cattgcagta tattgacctt tcatgtcaga agttcctcta
    23881 ccatatatct ttccatcaac tatttttcct tcaaaaggag gaacactcca tttacttgca
    23941 tctggaactg gaactgtatc tatatgtcca tcaaataata ttttcttacc tggcttgtta
    24001 ccttttatac atcctactat atttccatat ctatctcttg accaactatc aaaacctaat
    24061 ttttcaaaag actcttctat tgcttttaca acaccttctt catttccaga agaactagga
    24121 ttttgaatta atttttggca tatttcagtt acttcttgtt ttctttgttc gtttaacatt
    24181 tcattatccc cctaaatttt ttataatgta tgtattttat atacttatat attttctaaa
    24241 ttttagaact tatatatctt ctaaatatgt aaaccaatat ctaataattg cattttagta
    24301 attccttata tacttggata ttctccatcc caaactatac ttctatattt gtcagggtca
    24361 gtatctcctt ctgtgcttat taaaagtatt cttgaatttt catctaattt taaatctttt
    24421 cttaaatctg ctaaatcttc tctttccata gctgctacta aaagaccagt tgtaactgct
    24481 ccagattctc cagaaattac cttttcatca ccatttaaag gattacctaa tgttctcata
    24541 cctttagcag aaacccagtc tggtgctgaa acaaatgctg ctgcatgatt ttttaatact
    24601 tcaaatccta tagtatttgg ttctccacaa gcaagccctg ccattatagt tggcatatct
    24661 cctccaacaa atcttggttt tccatctcca gcttctgctg atttatagta acaatcagct
    24721 tcatcagcct ctactactac tgttattggg cattcatcat atattgaagc aacataccct
    24781 tgaactgcac cagcaagtga accaactcct gcttgaacaa atacgtgtgt tggtctatct
    24841 actccatatt cttttaattg ctctatagct tcttgagcca tagttccata tccttgcatt
    24901 atccatgctg gtatttcttc atatccgtcc catgctgtat cttgaaccat tactccatgg
    24961 tcatcagctt ctgcataatc attagctaat cttactgcat catcataatt taagtctgtt
    25021 atactagcat ctgcaccttc tcctttaatt ttatttaatc taaattcaga agaacctttt
    25081 ggcattaata caacagattt ttgacctaat ttattagctg tccaagcaac tcctctaccg
    25141 tgatttccat ctgtagctgt aaagaaagtt atttctccta atttttcttt tatttctttc
    25201 gaagtcaatt tgtcataccc taactcagat atatctgtat ctaatctttg agctaagtat
    25261 ctacccatag aataagaacc acctaatact ttaaatgcat ttaatccaaa tctataagat
    25321 tcatctttta catatactcc tgcaacacct aatttttttg ctaaaccttc taggtttgct
    25381 aatggagttt ctttatattg aggaaagctt ttgtgaaaat ttctaacctt agttatttct
    25441 tcttcattta aaaatttgat acaattttcc ttatcgccct ttggcaaatt atttactttc
    25501 catttaattt cttttaacat ctaaaatacc tccaaattat tgttaaattt ttatacttta
    25561 atatataagc aattaacatg ccaacactaa atatatacta gatatttttc tatgactctt
    25621 tagtatagaa attgcaatgc ttttattatt ttttcttttc tatctttagt tcatacaatg
    25681 tatgtagaat ttaataacta aaaaaccttt tctatcttct cactttttaa ttctcatttt
    25741 taaaatttaa aaataaatct caaaacactt tgtttctata ttttttaata taaaatctat
    25801 aaaatctaaa ttaaaacata aaatagtgat gcaataatct attacatcac tatttgtata
    25861 tattcaataa tataataaat ctttagtggt ctctaagagg tgatttttca tcttttttaa
    25921 catctaattc ttcttttacg acattccatt tttcaagacc aaacttagaa accataactg
    25981 cctctgctgc accttttcca agtcttttta ctgtgtccat acctgtctca tcctcttggg
    26041 caccttttgc ttttccatct ttactccata ttgtaccacc tatatagcat ccacctaaac
    26101 ctccagacac taacatttca tgcattagga agaaatttat tataggaagt tttgtcaatt
    26161 cttggccacc atatctagtt ccaccagtag ttatagctgc accaacctta ttttgaagtt
    26221 ttcctggatg aactaaatac attggacgaa gtctattaaa tactgctgta agttgagcag
    26281 ttatattcat atcataaact ggagaaccta ctataattcc atctgcctcc aatatttttt
    26341 gctctaattc ttggatatca tcttttataa tacacatagt ttcttttctt atacatgcat
    26401 cacaatgtac acaaggactt atttttttcc ctctaactga ccaatactca gtttctatac
    26461 caggtatagt ttctgcttct ttcaaagctt ctaacactgc atattctgtt gctcctttac
    26521 gtggacttcc acaaatacct aatatctttg ccataataat atctcctcac caaataaatc
    26581 tatttttatt atctatttac aaatacaata aattgttatt tctgctttaa tttctactat
    26641 tttaatttta ttggtaatga atgtatctct acatcagttg cattatatac tgcatttgca
    26701 acagctggcg caactggtac aacggcacat tctccaatac tcttaccacc aaaaggccca
    26761 gctttttcat aaccatctac aaatgcaact tgacattttg gcatatctac agttctaaat
    26821 aatttatatg ttttaaaatc agtagcttta ggtctacctt gttcatcaaa tgccaattct
    26881 tcactcaatg cgtatcctag acccatatga atcccacctt ctaattgtcc ttctaaattt
    26941 agaggattta taactctacc aacatcatgt acagctacaa aatcaactac ttttatatcc
    27001 ttagtttctt tatctactaa aacttcagca aaatgtacac cataagaagt acgtccagct
    27061 ggtgaagaat aatcttcaac aacagttaac tctcttaatg atttactttg actatatact
    27121 gcgacatcag aaagtgatgc ttttacattt tcatcaagtt tactaattac acatccattg
    27181 tctagatata aatcttcttt tgatgtttca agtaattttt ctgcttcttc taatataaga
    27241 tttttcaatt tctctgctgt ctttttagct cctccacctt ctacaaatac ccctctactt
    27301 gcatagtcac caaggttgaa tgtacatgca tccgtatcag tttcaaatgt atcaacttta
    27361 tcaggtgtta ttcctaaaac ttcagctacc atcattgttt gcatagttac aacaccatta
    27421 cccatatcat gagctcctgt tagtagtgtc aacgtaccat cttcatttaa tttaagagtc
    27481 aatgtaacaa catctctatg tgcaccaaaa actccattac catgtgcacc tattgccata
    27541 cctatacctc ttaaatattt tccttcttct tttggaagtt ttttcttttc atcccactta
    27601 aacatcttct taccttgctc tatacaatcc aatactctag gatttccaag agaaccgtgg
    27661 aagattatat cgacatcatc tggctctact gcatttttat tttgaaaatc gactaaatcc
    27721 atacctattt cctttgctat tttcgcaaat tgagcttgtt gagccataaa tatttgaggt
    27781 gacccatagc ctctcatagc tcctgctatt ggtgtatttg tatatacagg catcccagta
    27841 aactttatat ttggtatttt ataaacttta aatactttat gactaagtgc tcctataaca
    27901 tttaaagcac ttgatgcata tgctcctgta tttgtatata tttttatgtc ttgtgctatt
    27961 acttcaccat ctttatttac accagttttt aattttacaa aagacccatg acgagttctt
    28021 gtcgatatca tagattcttt tcttgtaaga accattttaa ctggtcttct tgtcattttt
    28081 gataatgcgg ctgctactgg ttcaattgta agttctaatt ttccaccaaa tgagcctcca
    28141 atagcaggtc ttataactct tactttattt aatgacatcc caaaaatttg agatagtatt
    28201 attctaaatc caaatgtatt ttggcaaggt gtatgtacag ttaatttatc attataatca
    28261 tagtgtgcaa ttacactatg agtctctatt gcactatgat gtattgctgg agtagagtat
    28321 tcatcttcaa atatatagtc acattccttg aagccttttt ctacatctcc cccatttatg
    28381 ttgttttgag aaactatatt tgaatctcca tgtatgcaga tagcatcttc ttttattgca
    28441 tcttgtatag taaatacagc tggcaattct tcatattcaa cttttataag ttttacagct
    28501 ttctctgcta tttctggagt ctctgcagct actgctgcaa cacggtcacc aacaaatcta
    28561 actgtatctg aaaatataac ttcattttca ggtatattgt gctcataaaa tcttaatgaa
    28621 ccattatatt ttctttgtga tgtattgaga taagtagcta tagctctaac acctactact
    28681 ttctcagctt cacttgtatc tatacttttt atttttgcat gtgctacagg acttaaaagc
    28741 atcttagcgt aaagtacatt ttgtggtttc atatcagcca cgtatttcat ttgaccagta
    28801 acttttaaag ctgcatcttt tagagggtat gattttccta ttaccttttc cataattatc
    28861 taccccctaa tctagctgca gataatttta cagcttctat aatctttaca tatcctgtgc
    28921 atctacagag attttcttta aaagcttctc taatttcatc ttcattagga gatgcatttc
    28981 tatttaaaag agcttgtgtt gttataatca taccaggagt acaatatcca cattgtacag
    29041 ctccaacttc tataaaagct tcttgtattg gatgaagatt ttctccatta gcaaaacttt
    29101 ctatagtgta tataacttta ccttcgcagt tttttgcaag aagtttacaa gatttcatgt
    29161 caactccatc tatcaaaact ttacatgctc cacaactgcc actattacaa ccttgtttcg
    29221 ctccagttag atttaatttt tcacgaagta catgcaaaag agtttcattc ttttcaactt
    29281 ctatttcata catgtaatca ttaatattta attttatttt ttccattttc tcctcctaca
    29341 gataaactaa tgttgtaata gaatattatt acaatcttat tttaatatta gtataagcta
    29401 ttccacttat gtccttccat tctattagtt acattagctc tcttacataa ttcttctgct
    29461 gcatgttgtg cattaagcaa cacttgttct tcactttcaa ttgtagttac ttttccattt
    29521 tcaagtatta catttccatc aactaaaaca ctctctacat tgtgcatact agctgagtat
    29581 accaaagttg atacaggatt gtgaagaggt attgattttg gagaaagcat tgagttaaat
    29641 attactaggt cagctttttt cccaatctcc aaagaaccta tttcatcttc cattctaaga
    29701 gttcttgctc cctcaattgt agccatttca agaactttct ctgcagaaat tgccagaggg
    29761 tcacaattat ttactttgtg ttgtaaagct gttaatttca taagctctac catatcttgt
    29821 gcgttattac ttgctgcacc gtcaagacct aaactcacat ttataccttt ttttaacatt
    29881 tctggcacag gtgcaacacc agaagcaaga tacatattac ttgctacatt atgagaaact
    29941 tttatgtcat actttttaag catttccatg tcttcatcag ttatacatac acaatgtact
    30001 gctacaactt ctggacctac tataccccat ttttcaagta attttatatc tatttctcca
    30061 tgtatatcct ttgttgctgt tcttgcaaat tctgtttcag atatatgaac tgtaaaatat
    30121 gaatcatatt ctttaactat attccaaagc atcttaccca tttcttcaga tatagcccac
    30181 attgaagaag gagctacaca gatttttatt cttccatttt ctgaattatg atatttttcg
    30241 aatacccttc tcaaatcttt ttcaaccgtt tccacatctt ctataagctc tttgtgaata
    30301 cctaaatcta tacaacctct acctacaacc cctcttatac ctaaatcttt atatgccttt
    30361 actattccat ctgtaagtcc tggtctattg tgagtatgca tataatcaac cattgtagtt
    30421 ataccacttt ttaaaccttc catacatcca agcattgcag catcataagt atcttgttct
    30481 gttaagaatt ttgctgatgg aaacatcatt gtatttaacc actcatgaag tgccatatca
    30541 tcacctaaac cttttaataa cacttggaac aggtgattat gagtatttat aaagccaggg
    30601 aatattactt ttccattagc atctataact tttttagcat caagatactt aggctcaata
    30661 tcaactgtat ttcctatgtc caagattctg tcaccttgaa tagctattgc tccatcaaat
    30721 ataacatctc tgtctttatt aactgtaaca attattgcat tttttattag tatatcaatc
    30781 atcttaaatc cccctttgaa tactttcatt acaacatttt accatatggt tttctcatat
    30841 tatatctaat acatttatcc aatattttcc tcaagatttg aagtaacgtt ttcagcactt
    30901 ttacgtgact ttaatttaaa taatgtttga agtaatatag ctattattgc tccagaaact
    30961 atacttgacc ctccaaggac agttccaatt gtttctggga attggtctaa aacttgtgga
    31021 gcagttgtaa gacccatact tgttgctata gatacacctg ctataagatt gttttcttca
    31081 gtgaatccat ccatactcat aatagagaaa ccagacattg ctattgatga gaaaactact
    31141 aaagttgctc caccaacaac acaagatggt atagttgtca ttattgcacc caatgctgga
    31201 gatatccctg ctagtaataa tacaagtgcc cctagtgcta ttacaaatct acttgtaact
    31261 ttgttcatag atacaattac tgtattttgg ctaaatactc cagttggaag agctgcaaat
    31321 agtgatgaaa ttatagaagt tatagaattt cctaaaacaa ctgatgctaa ttcttcgtca
    31381 gttacctctc tatccattgc tcctactgta gctattgtac aggcacccat catatcagct
    31441 atacctatta tgtaaataat agtaaacatt actattaact ctggtctaaa ttctaatcca
    31501 aaagctgctg gtgttggtaa agatactata gctgctcctt gaacggctga gaaatcaacc
    31561 aatcctaaaa ctaaagatat agcataacct actaatattc ctattaatat tgaagaattt
    31621 tttactaaac ctttaccgta tttatttatc attattatta caaaagcaac tataactcct
    31681 actgtgaagt ttattgggct tccaaatgtt tgtgtgcctt ctcctccagc taaattcttt
    31741 atagctgttg cgaatagtcc aagtcccata catgctatta tagttccaga aactattgga
    31801 gtgaatatat gtctaatttt cttaactcca aatcctacaa agaatacgat taccccagca
    31861 gcaatctgtg ctccaaatag agctgctaaa ccatctttag ctgctactga aagacaagct
    31921 cctaaaaata cataactcat tcccatcatt acaggtaatc ttgaacctaa cttaaatcct
    31981 ttaaataaag gtattggata taactgtaaa aacgttgcta aacctgctgc taacatagaa
    32041 ccctgaatca acattgttgc ttgcccctgg ttaagtccta ccacgtttgc tattaatatc
    32101 gcaggtacca tatttcctac tatcattgct aacagatgtt gtaaggccaa aggtattgat
    32161 tcctttagtg gtggtatccc atcgacatca tattttgaag tattacgtgt tttcataaaa
    32221 taaatcctcc catacataaa tatcttgact aaatattttt ataattattt tctataaata
    32281 tttttatgac catgaattta ttgctcaacc gataaacaca gctaaactga gctattttta
    32341 taaaaaatta acaaatttct aaatattccc tccccgattt tcaacttaaa tgaacattaa
    32401 ttgcctggta tatatttatt tgttaaattt tttattaaaa tgaatagcta tcaaaaataa
    32461 tctaacaatc tcatactaaa taatttaaac aattctttta aattattata tcttaattag
    32521 tctcttccat aacagctctt tctttagcct catcctctag acttttattt ggtattatta
    32581 gatttaaaac gaatgcaacc aatgttgcaa ttactattgg agattctcca aatactaact
    32641 ttacaaatga aggaaatgcc tcttgggctg ctggtactga tgttattccc atgcctaagg
    32701 caattgccaa accaacaatg gtaatatttc ttgatgacaa ctcttctgta ataattaact
    32761 ttatacctgt cattgttatc atactaaata tagatattgt agctcctcct aaaacagaat
    32821 atggtatagt agtcattaat gcaccaaatt taggcacaaa ccccgacaat aacataaata
    32881 taccagctat tccaagcaca aatctactta ttactttgtt catagctacc atccccacgt
    32941 tttggctata tgatgatggt ggtaaacctc caaacaaagc tcctatcata gtacaaattc
    33001 cacttcctat tactccactt gataattcct tatctgtgat attcctatcc atgcctccca
    33061 ttgtagtagc tgataaatct ccaattgctt gaacagcatt gattatactt acaattacta
    33121 ctgagattat tacaggcata tcaaattcca tcccaaattc aagcggttta ggtatcgcaa
    33181 accaagttgc ctctctaata gggtcaaaat ttattatacc cagaactaaa gatacacaat
    33241 atccaactat aattcccaaa aatattgctg ccaattttgc atatcctttt gcaaattgac
    33301 taagacctat aactaccact aatgttatag ccgctactgc ccagttttgc atagaggcat
    33361 aagtaggact atttacacca cctgccatat aatttattgc tataggatac aaagataatc
    33421 caattgtaaa aaccactgtt cctgcaacta tattcggaaa aaattttctt atctttttta
    33481 tgaatatccc tattaatact gtagccactc cccctattaa ttgtgcaccc aaaatgcttg
    33541 ctaatccata atttcctccg actgctacaa gtgttggtac ataagtaaaa ccaactccaa
    33601 aaattatagg caatcttgaa ccaatatttc ctattggata tagttgtata agtgttgata
    33661 taccagctat tattaatgca tattgcacta aaagtgttat ttgtgtaggg ctaacaccca
    33721 cagctcctcc tacgactata ggtactgtaa cagttccaac tatcattgct agtatatgtt
    33781 gcattgatag tggcaaacac tttaaaattg gtggccttcc atcaatatca aacatagaaa
    33841 cattcttttg atatttactc aaggttatca ctcccaacta ttttttaatg acagttatta
    33901 ttatctcaca caacatcctt tcttttttta ttttgtcatc tcaacttaat atgaagcaat
    33961 tataatgcca attttttaac ataattgttt tacatatata atttttatta tatttgttag
    34021 tatttgataa tttattaaag catttatttt tttaaattct tttaaatttt ttttattttt
    34081 ggataataaa atgctattac acaaaaaaac acttagaaaa tagttttcca agtgtttttt
    34141 atcaatttta taatttcaaa ttttagaatt gagaataaaa agcctaatta ttatacatct
    34201 atttttctgt acaatgtagc tagtgatatt ccaagttttt tggcagccag ttttttagac
    34261 ttagtatcat ttccgtaaaa ctttaacact ttctttatat aggctctttc aaactcttca
    34321 agtgtaagta tgtcttgttc catacttatc tcatagtcac tttcctcaag taactttata
    34381 tttatattat ttaacttaaa atattcaagt atctttctat ttattattcc tttatgtatt
    34441 attccatctt cctcaagaag gtttaatgcc agttctatag tattttccaa ctctctaata
    34501 tttcctggcc aaggatactt aagcaacatt tgttccacat ctggctctat atggtacacg
    34561 tttttcttca tctttctcga atatttgtct ataaaattgt ttattaatat ttgtatatcg
    34621 tctcctcttt ctctaagtgg aggcacttct aaaggtatta cattcaatct atagtataag
    34681 tcttctctaa atttattttc cttaaccaac tcaaataaat ctctattagt agctgatatg
    34741 attctaacat ctatatcaat tagttcattt gaacctattc tcgtaaactt cttttcctgt
    34801 aataccctca ataactttga ttgtagttga attggcatat ctcctatctc atctaaaaat
    34861 acaacccctc cattggccaa ttcaaactta ccaattttac cttttgaatc tgctccacta
    34921 aaagctcctt ttgtatatcc aaaaagttca ctttctagta aaggttctgg tatagcagca
    34981 cagtttatag caacgaatgt tttattccct ctgtttcctg cgagatgaat ggctcttgct
    35041 attaattctt ttccagtgcc actttctcca gttatagcta cagtagaatc actatttcca
    35101 attttacaaa ttctattctt aagagcacgc attacatcag actctccaat tatggagtct
    35161 actgttgttg ttccccaaat attatatact tccattccac catacattac tgaatcactg
    35221 tgtttgtcca taaaatatca actccaaata agtattctat ataataatca ttcacattat
    35281 ctatttaatt atatcataac agaaaagctt agttataatt taataatatt attttaaaac
    35341 aaaacttaat aaaaagtata tctacttagt tttaatttga tagatatact ttcttc
//
LOCUS       DAGQVA010000042        35364 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.042, whole genome shotgun sequence.
ACCESSION   DAGQVA010000042 DAGQVA010000000
VERSION     DAGQVA010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.042"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            130..498
                     /locus_tag="MIV85_002165"
     CDS             130..498
                     /locus_tag="MIV85_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBY2961499.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            501..872
                     /locus_tag="MIV85_002166"
     CDS             501..872
                     /locus_tag="MIV85_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBY2961500.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(1017..1472)
                     /locus_tag="MIV85_002167"
     CDS             complement(1017..1472)
                     /locus_tag="MIV85_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961501.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(1511..2776)
                     /locus_tag="MIV85_002168"
     CDS             complement(1511..2776)
                     /locus_tag="MIV85_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBY2961502.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            3246..4697
                     /locus_tag="MIV85_002169"
     CDS             3246..4697
                     /locus_tag="MIV85_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBY2961503.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(4895..5536)
                     /locus_tag="MIV85_002170"
     CDS             complement(4895..5536)
                     /locus_tag="MIV85_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBY2961504.1"
                     /translation="MTDNYIFDSYNNLVDGLSAYLGEGYEFILYKFNGVHYSINKIAN
                     GKYNTVKEGDIITDFDLALINKLENDADGDFISYFNRNKLGEPLKSTDIVIRGVDNKI
                     IGLLCIHFYLNTPLTRIIGSYIPEHNAMQSAPVLENIVEDTDEVILKSYQDAKVIVEN
                     DSNISSNDKNKSIVSILNESGIFKIKDSVVKVADLMGLSKNTIYMHLRNLNKN"
     gene            6010..7389
                     /locus_tag="MIV85_002171"
     CDS             6010..7389
                     /locus_tag="MIV85_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2961505.1"
                     /translation="MAQDKIVVEILENIGGKENIKEVAHCMTRLRIKVCDSSQVNQEK
                     LKKIKGVLGLVLKGEQYQIVIGPNVSQVYNTLNEVIGIIPEKDSKKTISEGKQNSIAK
                     ILDTIAGIFNPIVPALAGAGLIKAILALLVASKFLSADSETYIILNTISDGVFSFLPF
                     MLAYSAAKIFKMNTYVAVAIAGAMLHPNFINLIQQGLTKISFIGIPMSLIQYNGSVFP
                     IVLTIWFASYIEKGVDKITPKALKIILVPALTILFAAPIALIIIGPIAQMLGNYIAGG
                     ASILFERGGIFAGLIYGGIYSFMVVTGLHHGMVPVLVDGITRYGFNYISPVSGSSNMA
                     QAGSAFGVWLKAKDKDLKAVAATATISALTGVTEPAIYGVNLRLKKPFLCAAIGGAAG
                     GGFAAYFQCKAFAMGGPSFLTLPMFIGEGGHVGLVAIAFTIAFIVSAIATYIVGFEEE
                     VTADSHANL"
     gene            7433..8167
                     /locus_tag="MIV85_002172"
     CDS             7433..8167
                     /locus_tag="MIV85_002172"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010990049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBY2961506.1"
                     /translation="MKIYLTKDYEEMSQVAAQMVLKYMYSNDNKRINLSITAGQTPKR
                     TYEILSEFVKNKPYFENVHYYNFDEIPIKGEKVGVTIRNLTNMYFREAQIPEERIHVL
                     DENNYQGFDRKIEADGGIDMVLMGLGWDGHFCGNLSGTVNSFDEETRAVSTYITDDMA
                     KLLTKSVGGNPEKLFDYYVTYGPKTIMHCKNIIMIVNGKHKAQILKQTLFGPLDLLCP
                     SSLLRLHPNFTLIVDEEAASEIKDLI"
     gene            8256..9455
                     /locus_tag="MIV85_002173"
     CDS             8256..9455
                     /locus_tag="MIV85_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006875852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2961507.1"
                     /translation="MYNHMKKVFQGLEGGLFSSVEKADVGDSYQKLGEQGVSLMGWAD
                     PFFPDYCIPRHILDAATLAISSNMSTHYTAPVGNDLLKIEIAEKLKEVNNLDVDFKRN
                     ILITPGSDSGLYYSMLPFINEGDEVLIPTPCYPNNIQNTKLMGGVPIFVELKESDGYQ
                     IDITEFEKRLTNKTKLVVLTHPNNPTTTIFNKESLEKLAKFIIDNDLILICDQAFEDF
                     TFENELITPASLEGMFERTVTIFSTSKGMGLSGFRVAYMVCSDKLMDKYYGAAVTVLG
                     ATNTVAQMSTIEAFKDRSFMEDFERVFDKRRQEAYKIINEIPNVSMQMPESGFLGWIN
                     VSKLGTSSEIQKYLVDEAKVCINDGINYGPGGEGHLRIILGSYKDDSKVIGALNRIKD
                     ALIKKQQ"
     gene            9479..9961
                     /locus_tag="MIV85_002174"
     CDS             9479..9961
                     /locus_tag="MIV85_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2961508.1"
                     /translation="MLSIFKSKKNDNKLKAFASGKVIPIEDVDDNVFSSKMLGDGIAI
                     YPTNEYVVAPCDAEVNIIMKDTKHAVGIKLFNGMEILFHVGIDTVSMNGEGFEIFVSP
                     GDKIKRGDKLISFNSKLIKEEGLQDVVIMVVTNSEQYKNIKYHIGLEAVIDDTIIAEI
                     "
     gene            complement(10279..10876)
                     /locus_tag="MIV85_002175"
                     /pseudo
     CDS             complement(10279..10876)
                     /locus_tag="MIV85_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11120..11548)
                     /locus_tag="MIV85_002176"
     CDS             complement(11120..11548)
                     /locus_tag="MIV85_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961509.1"
                     /translation="MKIHSIQNLTLDTRNLIKKYSLTLNEDLIWEFKHGKYHTIKYFT
                     HKFAVKESVLALLFNIHKLCYAKIKYFESSFSKYEPYKYSYQNEFVKCEMYDMNFMFH
                     KYSNIMIDLRNLQEIKTIEEFRLFCDYLESFEDNLQDLII"
     gene            complement(11949..12410)
                     /locus_tag="MIV85_002177"
     CDS             complement(11949..12410)
                     /locus_tag="MIV85_002177"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBY2961510.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLD"
     gene            complement(12515..13708)
                     /locus_tag="MIV85_002178"
     CDS             complement(12515..13708)
                     /locus_tag="MIV85_002178"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBY2961511.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(13731..14396)
                     /locus_tag="MIV85_002179"
     CDS             complement(13731..14396)
                     /locus_tag="MIV85_002179"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBY2961512.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(14430..15542)
                     /gene="ribD"
                     /locus_tag="MIV85_002180"
     CDS             complement(14430..15542)
                     /gene="ribD"
                     /locus_tag="MIV85_002180"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBY2961513.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(15674..15795)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            15984..18467
                     /gene="recQ"
                     /locus_tag="MIV85_002181"
     CDS             15984..18467
                     /gene="recQ"
                     /locus_tag="MIV85_002181"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBY2961514.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      18556..18667
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            18809..20110
                     /gene="thiC"
                     /locus_tag="MIV85_002182"
     CDS             18809..20110
                     /gene="thiC"
                     /locus_tag="MIV85_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBY2961515.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            20164..20358
                     /gene="thiS"
                     /locus_tag="MIV85_002183"
     CDS             20164..20358
                     /gene="thiS"
                     /locus_tag="MIV85_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBY2961516.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            20351..21154
                     /gene="thiF"
                     /locus_tag="MIV85_002184"
     CDS             20351..21154
                     /gene="thiF"
                     /locus_tag="MIV85_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBY2961517.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            21217..21987
                     /locus_tag="MIV85_002185"
     CDS             21217..21987
                     /locus_tag="MIV85_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBY2961518.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            22004..23107
                     /gene="thiH"
                     /locus_tag="MIV85_002186"
     CDS             22004..23107
                     /gene="thiH"
                     /locus_tag="MIV85_002186"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBY2961519.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            23108..23797
                     /locus_tag="MIV85_002187"
     CDS             23108..23797
                     /locus_tag="MIV85_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBY2961520.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            23985..25379
                     /gene="yfcC"
                     /locus_tag="MIV85_002188"
     CDS             23985..25379
                     /gene="yfcC"
                     /locus_tag="MIV85_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBY2961521.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            25896..27263
                     /locus_tag="MIV85_002189"
     CDS             25896..27263
                     /locus_tag="MIV85_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBY2961522.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            27288..27896
                     /locus_tag="MIV85_002190"
     CDS             27288..27896
                     /locus_tag="MIV85_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBY2961523.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            27944..28315
                     /locus_tag="MIV85_002191"
     CDS             27944..28315
                     /locus_tag="MIV85_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBY2961524.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            28494..28832
                     /locus_tag="MIV85_002192"
     CDS             28494..28832
                     /locus_tag="MIV85_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBY2961525.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            29298..29801
                     /locus_tag="MIV85_002193"
     CDS             29298..29801
                     /locus_tag="MIV85_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBY2961526.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            29848..30807
                     /gene="moaA"
                     /locus_tag="MIV85_002194"
     CDS             29848..30807
                     /gene="moaA"
                     /locus_tag="MIV85_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBY2961527.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            30811..31281
                     /gene="moaC"
                     /locus_tag="MIV85_002195"
     CDS             30811..31281
                     /gene="moaC"
                     /locus_tag="MIV85_002195"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBY2961528.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            31317..31748
                     /locus_tag="MIV85_002196"
     CDS             31317..31748
                     /locus_tag="MIV85_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBY2961529.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
     misc_binding    32179..32390
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            32553..33842
                     /locus_tag="MIV85_002197"
     CDS             32553..33842
                     /locus_tag="MIV85_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBY2961530.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            33896..34975
                     /locus_tag="MIV85_002198"
     CDS             33896..34975
                     /locus_tag="MIV85_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBY2961531.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            34996..35361
                     /locus_tag="MIV85_002199"
                     /pseudo
     CDS             34996..35361
                     /locus_tag="MIV85_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
BASE COUNT        13484 a         3961 c         5940 g        11979 t
ORIGIN      
        1 ctcaaagtta tattagtaaa aattggaatt atttataata tactccaaaa tttaaaaata
       61 atggttgaaa aatctaatta agagtactat aatttaatta agtaattact taatcaaaac
      121 gaggtactta tggaaaactt ggttaaaata tttaaagcat tgagtgatga aactagactt
      181 aacatactta tattagtatc caagagaaat atatgtcaaa aggggatttc taaatatcta
      241 gggatttcag attctgctgt ttcacaacat ataaaaatat taaaagatgt tgggataata
      301 acaggatata aagaaggata ctatgtttta tatcatatta ataaagaatc atttaatata
      361 tgtgtagatt ttataaattc tatgttaagt aattctagtg aaagctttat agatgtattt
      421 gatgtaaata caatacatct aggatgcagt aaagaatgta aatctataaa aaaatgttgt
      481 aagagaaggg agaaataata atgaaagtat gtataccagt agaggagaat aaaggattgg
      541 atagtaaacc atatggacat tttggttctg ctccaatttt tgttgtgtgt gatttagaaa
      601 gtggagaagt taaatcttta gataatggag atttagatca tgaacatgga aaatgtcaac
      661 cattaaaagc attgtcaggg acagctgtag atgcagtagt tgttggagga ataggacaag
      721 gagctataat taaattaaat ggaatgggaa taaaagttta cagagcagaa ggtgatacta
      781 taagtgctaa tttagactta cttaaaaatg gaaaattagt agaatttcca tcagaccata
      841 cttgctcaca tgacggatgt ggacatcatt aaaaaaaaac agctgatgaa atatatactt
      901 catcagctat tttttctttt aataaatacg attttattct tttaaaacca aaatttagat
      961 ttttatattt tttgtagtat ccttaataat atttcaagtt tacaagttta ctacttttag
     1021 attttttttg tatgtttttc tatatagtca atatcattta atatgtcatt gagttcttta
     1081 ttaagtgttt ttaaatcatc accatctaca ttgtagttta aaaatagttc ctctacatta
     1141 tcaatgatag aattgacttt tctagtaact tcaacaaatg tcttaaagtt actactattt
     1201 ttagcattta gaaatttttt taaatccttt gatataaatg atactatttc atattcatca
     1261 ttaaatagac ctctaccaat aggatatggt tcaattctct gtaaaaaata ttggtcttta
     1321 gcattaatat tataagtata agatatttcc caaccgtctc ctaaatcaaa cttgataaaa
     1381 tataatgtac tacttacttt tgatattctt gtggcaccaa gctgtcttaa aagaacttca
     1441 atcgaatcac cttgaacagt attaatattc atatatacac atccccttta gtattattat
     1501 actatatttt ttaaaatttt ataattaaat aaacagtaga tataataata gatataatca
     1561 taagtggaaa acctattttg aaatactcct taaaagagat aggatgaccg tgtttattac
     1621 ctatacctgc tagtacaaca ttagcagatg ctcctattag tgttccattt cctccaagac
     1681 aagctccaag agatgttgcc caccatagtg gcattacatc aataccttca gcttgcatag
     1741 tcaaaataag aggaattagt gttgcaacaa atggaatatt atctaagaaa gaagagacta
     1801 tagctgacaa ccataatatc aacaacattg taaatacaag atgtccttct gtaagtccaa
     1861 tcaatgcttg agccaatttg tttattatcc caacttctac taatccacca actactacaa
     1921 ataatcccat aaagaataaa attgtagacc attcaatacc tgccataatt tcatctacat
     1981 cttgttttcc tattaaaagc attatagatg ctcctgtcag tgctacaaca gaagaatcta
     2041 tgtggattgt actgtgaaac ataaaaccaa aaagtatgaa tgctattaat ataaggcttt
     2101 ttataagtag aggtttatct ttaacagatt ttttttcatc tagttttaat attgcatttt
     2161 tagctctttc attcacaaca agttcttttc cataaataaa tctaaagcat attatagtta
     2221 tagcaagtat tactataaca gcaggaccta aatttattac aaaatccata aaactaagat
     2281 tggcagcact accaatcata atatttggag ggtctcctat aagagtagct gttcctccta
     2341 tatttgaagc taaaatctgt gttattaaaa atggaactgg attaagtcct aatatttgtg
     2401 taataactat agtcattggt ccaataagta agacggttgt aacattatct aatacagctg
     2461 ataaaatagc tgttataata gcaaagcaaa tcattatctt ccatgggtca cccttagctt
     2521 tctttgcagt ccagatagct atatattcaa ataaccccga gtttttgaca acagctacaa
     2581 atagcatcat accaactaat acaccaatag tattgaaatc tatatggctt aatccttcat
     2641 caagtgtaag tatattgaat attatcatta atagtgcacc accaacagct gctacggatc
     2701 tgtttacctt ttctgtaata atagctgcca taactattaa aaatatacat atagctatta
     2761 tttgttgaaa ttccataata taagtacctc catttgtatt attttgtgcc taatgctagt
     2821 actatatata gtattacttt tttattgttt tttcaatgga tgtatgaaag tatattattt
     2881 aacaaagttt ttgaaaaatt gacagaattt aaagaaaatt tttgttattt aaataaattt
     2941 taaaattatt ccattgataa taatattaaa cgacaaacga aaaaatatac cctttaaact
     3001 agaatttatt gtatctaata acaattataa aatattaaat atatctatat tataaaaaca
     3061 ataaaaaaag gtttgatttg aatataaaac tgcaatatat taaaaaaatt attcatttta
     3121 aaccttgtaa tttgatttta taaatattat aattaaatta atgaattttt aacaaggaat
     3181 tattcatttt tttgatttta agatttattg agaaaacaaa actaaatagg ggggtaatta
     3241 atataatgga ttttttcaat ggtattttaa cgagtattaa caatgcagta gtatttgtaa
     3301 acaattactt atggtcgtat atcttaatta taatgttagt tgtaattggt atttacttta
     3361 ctattaaaac aaattttgta caattcagat attttataga aatgtttaga cttctgggtg
     3421 atggtacagc gaataaaaat gcaaaaaagg aaggaaaaat ctcttcattt caagcatttt
     3481 gtataagtac atcttcaaga gttggaactg gaaatatagc tggaatagca attgcagtgg
     3541 tagcaggagg acctggtgct gtattttgga tgtggcttat agcattaatt ggttctgcat
     3601 caagctttgt tgagagtaca ttagctcaga tttacaaagt gaaagatggt caagctttta
     3661 gaggtggacc agcgtattat atggaacaag gtctaaataa aaaatggatg ggtattttat
     3721 tctcaatact tataactata tgttatggtt ttgtatttaa tgcagttcaa gcaaatactg
     3781 tttcacttgc atttaataat gcatttggaa taagtaaaat ggctatggga ataggtcttg
     3841 gaattttaac tgcaatagtt atttttggtg gagtgcatag agttgcaaaa gtttctgaaa
     3901 taatagttcc tgtatttgca ggattatata tattagttgc tttggctata gttgtaatga
     3961 atataacaga gataccaagt gttatagcat tgatagttga aagtgcattt gattttaaag
     4021 gaatggcgat tggtacattt atgggagttg taatgactgg agtgaagaga ggtctatttt
     4081 ctaatgaagc aggtatgggt agtgctccta atgctgctgc aacagcacat gtaactcatc
     4141 ctgtaaaaca aggtttaatt caatctttag gtgtttttac agatactata ataatatgta
     4201 gttgtacagc attcatggta ttattatatt caggttatag tagtagtgga gcaactggaa
     4261 ttgaattagc tcaagaagct ttaactcatc atataggacc agttggaaat atatttatag
     4321 cagtttgtat attcttgttt gcatttagtt ctatagttgg taattactat tatggtgaat
     4381 caaatatgga gtttatgagt ggaagtaaga ctaaacttaa tgtatttaga gtttttgttg
     4441 taggtatggt tttatttggt tcacttactc aagtggatgt agtttggaat cttgcagact
     4501 tatttatggc attgatggcg ataataaact taatagcaat agcactttta ggaaaatatg
     4561 catttattgc tttaaaagat tatacaagtc aaaaaaaatc aggaataaaa gaccctgtgt
     4621 ttattgcaga tgaaatagaa ggcctagaaa aggtatcaga gtggcatagg gaattatctg
     4681 aggaacattt aggataaaaa atagtataaa attataaaac cattttgaaa gactagagta
     4741 tgtatatact ttatatgaat ataatattga attaatttat attactggaa tttttaattc
     4801 cagtaatatt tttttaatta caaggatatt atgatgactt aaagactgtg gaaaactctt
     4861 ttttagtttt cattattaat attaattgac aaatttagtt tttatttaaa tttcttaagt
     4921 gcatataaat cgtatttttt gataatccca ttaagtctgc aactttaaca acagaatcct
     4981 taattttaaa aataccactt tcatttaaaa tagaaacaat agatttattt ttatcattgc
     5041 tagatatatt agaatcattt tcaacaatta cctttgcatc ttggtatgat tttaaaatta
     5101 cttcatcagt atcttctacg atattttcta aaacaggagc actttgcata gcattatgtt
     5161 ccggaatata tgaaccaatt attcttgtta gtggtgtatt aagataaaaa tgtatgcaga
     5221 gtagaccgat tattttatta tcaactcccc ttatcactat atctgttgat tttaaaggtt
     5281 cacctagttt gtttctatta aaataactga taaaatctcc atcagcatca ttttcgagtt
     5341 tattaatgag tgccaaatca aaatcagtta taatatctcc ttcttttaca gtattatatt
     5401 taccattagc tattttattt attgaatagt gtactccatt aaatttatat aaaataaact
     5461 cgtatccttc tcctaaatac gcagataatc catccactag attgttataa gaatcgaaaa
     5521 tatagttatc agtcatgtta aaagtcatat gttacctcct aagaaatatc ttaatatcat
     5581 attaacatat aaaatgaatt taataaaata tatttcagtg aaataataaa tataatgaaa
     5641 aaaaaactat tgactgaaaa atatttcagt gatattatta aaatacagta aggcaaacgt
     5701 attattgaca gaatatataa aatgttaaaa atagtatcta ggaattaaac aaattaaagg
     5761 actagtgatt tgaatttttt tagtataata tgtgacttcc aattaatatt tattaaacac
     5821 caataaaatt gtaaatatgc ttaatgatat actttagcga tgaagtgaaa atattttatt
     5881 tttatgatta acctatagga attaatttag catactgttt agctagtaaa tctaaataaa
     5941 ttttagcttt agctgatatc atgttgaata aagtttctat tggattttgt ataacaaagg
     6001 agtggggaga tggcacaaga taaaattgtg gttgaaattt tagaaaacat tggtggtaag
     6061 gaaaatatta aggaagtagc acattgtatg actagactga gaataaaggt atgtgatagt
     6121 tctcaggtaa atcaggaaaa actaaagaaa ataaaaggtg tactaggtct tgtattaaaa
     6181 ggtgagcaat atcaaattgt tataggtcct aatgtatcac aagtgtataa tactcttaat
     6241 gaagttatag gaattatacc tgagaaggat agtaaaaaaa caatatctga aggtaaacaa
     6301 aatagtattg caaaaatatt agatactatt gcaggtattt ttaatcctat agttccagca
     6361 ttagcgggtg caggtctaat aaaagctata ttagcattac tagtagcatc aaagttttta
     6421 tctgcagata gtgaaaccta tataatatta aatacaatat ctgatggtgt attttcattt
     6481 ttaccattta tgttagctta ctcagcagct aaaatattta aaatgaatac ttatgttgct
     6541 gtagcaatag caggagcaat gctacatcct aatttcatta atttaattca acaaggctta
     6601 actaaaatat cttttatcgg tattccgatg tcactaatcc agtataacgg aagtgtattt
     6661 ccgatagtac taactatttg gtttgcatcg tatatagaaa aaggagtaga taaaataaca
     6721 ccaaaggcac ttaagataat attagtacct gcattgacta ttttatttgc agctcctata
     6781 gcattaatta ttattggacc aatagctcaa atgctaggaa actatatagc cggtggagca
     6841 agtatcctat ttgaaagagg aggaatattt gcagggttaa tttacggagg aatttattca
     6901 ttcatggtag taacaggatt acatcatggt atggttcctg tattagtaga tggaataaca
     6961 agatatggat ttaactatat aagtcctgtg tcaggtagtt caaatatggc tcaagcagga
     7021 tctgcatttg gagtatggtt aaaagcaaaa gataaagatt tgaaggctgt agcagctaca
     7081 gctaccatat cagcattaac tggagttacc gaacctgcaa tatatggtgt taatttaaga
     7141 ttaaagaaac cgtttttatg cgctgctata ggtggtgcag caggaggtgg atttgctgca
     7201 tatttccaat gtaaagcatt tgctatggga ggtccatcgt ttttaactct tcctatgttt
     7261 ataggagaag gtggacatgt aggattggta gcaatagcat ttacaatagc atttatagta
     7321 tctgcaatag ctacctatat agtaggattt gaagaagagg taacagcaga ttcacacgct
     7381 aacttataat aaagagaaat tatttaacat atcaaaaagg agattaatta ctatgaaaat
     7441 ttatttaact aaagattatg aagaaatgag ccaagtggca gcacaaatgg tgttaaagta
     7501 tatgtacagc aatgataata aaagaataaa cctttctata acagcaggtc aaacaccaaa
     7561 aagaacatac gaaatattaa gtgaatttgt taagaataaa ccttattttg aaaatgtaca
     7621 ttattataac tttgatgaaa taccaataaa aggcgaaaaa gttggagtta ctataagaaa
     7681 tttaactaat atgtacttta gagaagctca aataccagaa gaaagaatac atgtgttaga
     7741 tgaaaataat tatcaaggct ttgatagaaa gatagaagcc gatggtggaa tagacatggt
     7801 attaatggga ttaggttggg atggacactt ctgtggaaat cttagtggta cagtcaactc
     7861 ttttgatgaa gagacaagag ctgtttcaac ttatataaca gatgatatgg ctaaactatt
     7921 aacaaaatct gtaggtggaa atccagaaaa attatttgat tactatgtga catatggacc
     7981 taaaacaata atgcattgta aaaatataat aatgatagta aacggaaaac acaaagctca
     8041 aatattaaag caaacactat ttggaccatt agatttatta tgtccatcat ctttattgag
     8101 attacatcct aacttcacat taatagtaga tgaagaagca gcatctgaaa taaaagattt
     8161 aatataaata agtaaggaat taaaattaaa aatgaattta ggtgcaaagt aatattttat
     8221 tttgcacctt tgctttaata aaaaggagaa taaaaatgta taatcatatg aaaaaagtat
     8281 tccaaggatt agagggtggg ttattttcaa gtgtagagaa agctgatgta ggcgattctt
     8341 atcaaaaatt aggtgagcag ggtgtaagtt taatgggatg ggcagatcca tttttcccag
     8401 attactgtat acctagacat atattagatg cagctacatt agcgatatca agtaatatgt
     8461 caactcatta tacagcgcct gtaggtaatg acttattaaa aattgagata gcagaaaaat
     8521 taaaagaagt aaataattta gatgttgatt ttaaaagaaa tatattaata actcctgggt
     8581 cagactcagg gctttattac tcaatgttac cgtttataaa tgaaggggat gaggttctta
     8641 taccaacacc atgctatcca aataatatac aaaatactaa attaatggga ggagttccta
     8701 tatttgtaga gttaaaggaa tcagatggat atcaaataga tataacagaa tttgagaaga
     8761 gattaactaa taagacgaag ttagtagttc ttactcatcc taataatcca acaactacaa
     8821 tatttaataa agaatcttta gaaaaattag ctaaatttat tatagacaat gatttaatat
     8881 taatatgtga tcaagcattt gaagatttta cttttgaaaa tgaattaata acaccagctt
     8941 cattagaagg tatgtttgaa agaacagtaa caatattttc aacatcaaaa ggtatgggat
     9001 taagtggatt tagagttgca tatatggtat gcagcgataa attaatggac aaatactatg
     9061 gagcagcagt gacagtatta ggtgctacta atacagtagc tcaaatgtca acgattgaag
     9121 catttaaaga tagaagcttt atggaggatt ttgaaagagt ttttgataaa agaaggcaag
     9181 aagcatataa gataatcaat gaaataccta atgtatctat gcagatgcct gagtccggat
     9241 ttttaggttg gataaatgta tcaaagcttg gaacatcatc agaaatacaa aagtatctag
     9301 ttgacgaggc taaagtttgt attaatgatg gaattaatta tggtccagga ggagaagggc
     9361 atttgagaat aattttagga agctataaag acgatagtaa ggtaattggt gcattaaata
     9421 gaataaaaga tgctttaatt aaaaagcaac aataaataaa aaataattgg agtggagtat
     9481 gttatcaata tttaagagta aaaaaaatga caacaagctt aaggcatttg catcagggaa
     9541 agtaattcct atagaagatg ttgatgataa tgttttttca tctaaaatgt taggtgatgg
     9601 aatcgctatt tatccaacta atgaatatgt tgtagcccct tgtgatgcag aagtaaatat
     9661 aataatgaaa gatactaaac atgcagttgg aattaaatta tttaatggta tggaaatctt
     9721 atttcatgtt ggaatagata ctgtatctat gaatggagaa ggttttgaga tatttgtttc
     9781 accaggtgac aagataaaaa gaggtgataa attaatatct tttaatagta aattaataaa
     9841 agaagaaggg ttacaagatg tagttataat ggtagttact aattcagaac agtataaaaa
     9901 tataaaatat catattggac tggaggcagt aatcgatgat actattattg cagaaattta
     9961 aaaacagtta tttaagtaaa tacttagata atttagatat agttaaaatt aaatccttaa
    10021 aatcaaatta tttaattttt gtgtaatttt aactataaag ccgattaata atataaagta
    10081 tactaaataa tatggttatt atgattgtta ctgacaaagc ctaagtagat ataacaattt
    10141 gctctaattg agtattgcta tatctacttg tttttatatt taaaataaaa gagtctgcat
    10201 tgaaaagata attctgatga gagtaaatag ggtatttaat aatagtttaa ttctgactta
    10261 tcaagatgaa cctattcata tacctaaaac atctttaaca ccttctaaat tcatacaaat
    10321 agctgtatag gctgccttat tgattatttt tccgtcaatt tttactttgt agtgaacagc
    10381 atatataaat attatcgaat agattgtatc aagagctcta ttttgctatt cattagctaa
    10441 agatagtact ctgtcagtta tttttgaaac taatgcatga gatatatcaa ttccgtaaat
    10501 attatttaaa tgtatgatat atatcgcgag tcgacattcc ttttgagtac atgccaatta
    10561 cttggttctc tattccagaa atttcatttt cgtaattttg aataacccta ggctggaaat
    10621 catccctagg gatatttaat tttacctctc caaaatctga tttaacattc ttagctctat
    10681 atccatttct tgaatttgat gttgctttac tttggttatc atatctctcg tacattaaat
    10741 gatcttcaat ctctgactct aacattttgt gaattgtgct tgcgaataaa tcttttaaca
    10801 tctcttggat gtctttagta ttttttacat catactcttg aactaagtgt tttaatattt
    10861 aatttttgtt gtacataaaa aatgtgtacc tcctattttg gtaattagat ttaatatctt
    10921 gacttttagg agaatacaca ttttatttta cagaccctct tttctagaaa agtttttatg
    10981 aaaattgtga tataaattat taataaaaaa taattttata tttattttat tatgtaattt
    11041 agttttatta aaaatttttt attattggat atagattatc tattataaat tttatcttta
    11101 agtttattct cctaaaatac tatataatta aatcctgtaa attatcttca aagctttcta
    11161 ggtaatcaca aaataatcta aattcttcta tggttttaat ttcttgtaaa tttctcaaat
    11221 ctatcattat attactatat ttatgaaaca taaaattcat atcatacatt tcacatttaa
    11281 caaattcatt ttgataacta tatttataag gttcgtattt tgaaaaactc gactcaaaat
    11341 attttatttt agcataacat aatttgtgta tgttgaacaa aagtgcaaga acagactcct
    11401 taactgcaaa cttatgtgta aagtatttta tcgtgtggta tttaccatgt ttaaactccc
    11461 aaattaaatc ctcatttaaa gtaagagaat atttttttat aaggttacgc gtatctagtg
    11521 ttaaattttg tattgaatgt attttcataa tttattctcc tcataaatat ttaataagta
    11581 ttaaattata gtgttttatt attaattgtt cttaattata ttgtatggta aattaaaaaa
    11641 gtaataaaat agataattaa tatactagta atatatgcta taaataaaaa caatagctaa
    11701 aatagtaata tatatgtttt tatgatattt tatgtttagg gttatatttg taattatttt
    11761 aagcttctaa aagtagattt gatggataac gtataatttt agaaggatat gcaatttgtt
    11821 tgataagaac gtacatatga ttaaattaaa aatattaagt accaaaaaga agaaagatag
    11881 tttctccctt tggtacttaa tattttgtat cctttacact aatttttaat atttattaat
    11941 gatattattt aatctagaga cttaaataaa tttgccattt ctagcgcatt catagcacaa
    12001 tcataacctt tatttccagc ttttgtacct gctctttcaa tagcttgttc aatattttct
    12061 gtagttacga ttccaaatat aacaggtaat tcactgtcta aagatacttt ggctatccct
    12121 ttagagactt cactacatac ataatcataa tgagaagtag cccctcttat aacacagcct
    12181 aaacagatta tagcatcata cttaccactt ttagccattt tttgagcaac aagaggaatc
    12241 tcaaaagctc caggtaccca aactatttct atattttctg gagaaacgtc atgtcttaaa
    12301 agacagtctt cagctcctga taaaagtttt gatgttataa attcattaaa acgagaattt
    12361 attataccta tttttaaatc ttttccaata agttttcctt catatatcat ttttacttcc
    12421 tccaatttta tttatgttat agatttatat ttataaatat ctttaattta attataaaaa
    12481 actacttagt agaaaaatat catcatataa tcatttatat aatatctaaa agatgtccca
    12541 ttttatcttt tttagttttt aaatatagct tattaaagtc attaatttct tcattaatag
    12601 ggattctatt ttcgattttt attccatatt tctctaattg atttatttta tctgggttat
    12661 tacttaaaag atttatactt tttatgttta aattttttaa tatttgagca gccatataga
    12721 aatctctcat atcttcttca aatccaagca ttaaatttgc ttcaacagta tcgtaacctt
    12781 cttcttgaag tttataagcc ttaattttat ttaaaagacc aatacctcta ccttcttgct
    12841 tcatataaat taaaactcca cttccatttt ccacaatttt cttcatagaa gattctagct
    12901 gtaatccaca atcacatttt agagagtgga acacatctcc tgttaaacat tcagaatgaa
    12961 gtctaactag agtattttct atatttatat ttccataagt aagggcaatg tgttcttcat
    13021 ttgaataagt atctctatat cctatgattt caaaatttcc atattttgtc ggaaggaaag
    13081 cactagatac tttttctata gtagtttcat ttattttgcg gtattctata aggtctttta
    13141 tagtgatgat ttttaaatta tgcttttctt tgaaaatcat taaatcatca actcttgcca
    13201 ttgtaccatc atctttcatt atttcacaga taagaccaat ctctttaaaa cctgcaagtc
    13261 tagcaaggtc tactgaggct tctgtatgtc catccctgac aagaactcca ccagtttttg
    13321 ctattaaagg aaagatgtga ccaggcgttt tgaaatcttt acttgtagaa ttttcatcac
    13381 agaataattt tacagtttca gctctttcat atgcagatat accagttaga gtatctgctc
    13441 catctatagt aacagtaaag gctgtttgaa atgtatctgt attttctcta accataagag
    13501 gtatattaag acttttaaat tttttttcag tggcaggtag acaaattaga cctctaccat
    13561 atgtagccat aaaatttatt gattcaggag tagccatttc agctgccatc aataaatctc
    13621 cttcattctc tctactttca tcatcaacta cgattaccat tttcccattt tttatatctt
    13681 caatagcttc ttcaatagta ttaaacatgt aattcactcc tttattattt ttaaaaacca
    13741 tttttaaata aaaaatcttt atctatattt gatttatggt tactactatt agaatttaat
    13801 tccttgtagt tattagccat aaaattatta acatactttc caattacatc gctttctaaa
    13861 ttaacgaaat ctccaacatt ctttgtcaag agaatagtgt taattttagt atgaggtata
    13921 atagaaacct taaatatttc atcatctaaa tatgatatag ttaaacttac accatcaata
    13981 gcaacagaac ctttgagtat cattgaggat aaaagttttt tatcaggtcg tatacttact
    14041 aaaactgcat tttcatcttt ttcaaatttg cagatagttc ctttaccatc aacatgacct
    14101 gttactatat gaccaccaaa tcttgaagaa agactcatag ctctttcaag atttaccttg
    14161 tcatttgcat ttaataaacc taaatttgtg gaacgaattg tctccatcat aacatcggct
    14221 gtaaattcat tttttccgag gtttgaaaca gttagacaaa ctccatttac ggctatacta
    14281 tctccaagat ttgtgccatc taatatttta tttgatagta tggttacttt tccactctta
    14341 ccattagcag taatttttct aagtattcca acttcttcta ctatgccagt aaacatccta
    14401 acctcctata tgaatgtatt aacaaaaatt taatttaaaa catctgattc tataagaata
    14461 tcgccatcta tcaaagttac attattgatt gttaactgtg ttgaatctga caaatgattt
    14521 attccttctc cagaaacgaa tgtaggtgca tctttaccac ctataatctt gggtgataga
    14581 aataatttga ctttatcaac taacttattt ctaaagagac tgtcattgag agtagcacca
    14641 ccttcaacta gaacagaatc aatgtttaac tctcctaatt tatacattac aaactccaaa
    14701 tctactaagt tgttttttga aggagaaatt attgtttcaa cattattttc ttttaacata
    14761 gataatttta tactttcttt gcaacatgtg aaaactatag ttttactggt tttatcttta
    14821 accaaattac tattaagtgg caactttagg tgtgtatcta ttactattct tgtaggatga
    14881 gacacttttt cttgattgag cctacaagtt agtaaaggat tatcgttcaa aactgtattt
    14941 atgccaacca ttatactttg gtatttattt ctgtatttat gagttagata ccttgatgat
    15001 tcattagata tccattttga ttctagtgat tttgtggcaa ttttaccatc tagacttact
    15061 gctgatttta caatacaaag aggtcttttg ttttttatat gataaaaaaa tgcctcattt
    15121 aaatctcttg cttcatcttc taatattccc acagtaacat caatattgtt atcttttaat
    15181 ttttttactc cattaccaca aacaagtgga tttgggtcta atgtagatat tacaactctc
    15241 ttaatcttat tttgtataat tttatctaca caaggaggcg ttttcccata atgagaacat
    15301 ggttctaagt ttacataaag agtagagtct tttagacttt gtttagcact gtttatagca
    15361 tttacttcag catgattaga gccaaatttc tcatgatatc ctttgcctat tatattacta
    15421 tctttaacaa ttacacatcc aactaatgga tttggattta caaagccttc tccattttta
    15481 gccaattcaa tagctttttt catataataa atatcttttt ctttttgatt cacaaaattc
    15541 acaatatgta cacctcctgt ttaattggat aatttttaaa caaaaaaccc tgagaattaa
    15601 ctcagggttt agaataatct acaataaatg tttaataaat gtagaacaaa attgctctac
    15661 aaaaacactc attaaatatc ttcttccatc cagactttac tgtcggcttt ggaatttaac
    15721 caaatcaacc aagttttaca ttggctcgcg ggctataccg ccgattggga atttcaccct
    15781 accccgaaga ttaagtatta aatttatatt tagaatgtat cataaattat tttactttgc
    15841 aaactatttt tttaaaaaat atatgttaat atataatata gaatgtctat aaactttgaa
    15901 ataccacgat tgtgaatata aaaataaaaa tttgaacata atcaggaaag aagtctaatt
    15961 aatttaaatt aggagagtaa tatatgaata aaaaactttt agaaatacta tcaaaatact
    16021 atggatatac aagttttaga aaaggtcagg aatctataat aaattctatc ttaagcgaaa
    16081 aagatgtgct agctattatg ccaacaggag ggggaaaatc aatatgttat caaattccag
    16141 ctttgatttt agatggaatg acaatagtaa tttctccact tatatcactt atgaaagacc
    16201 aagtagatgc cttaaagact atgggaatta gtgctgcttt tataaatagt tcattaagta
    16261 gcaaagaatt taatgaaata ttaaataata ttagaaaaaa taattataaa atactctata
    16321 ttgctccaga gagattagat gcacaagagt ttattgagct aataaataat aacaatgtaa
    16381 gtcaagttgc gatagatgaa gcacattgtg tatctcaatg ggggcatgat tttaggttga
    16441 gttatagaag gatttctgat tttataaaaa atttgcctaa aagacctata gttacagcat
    16501 ttactgcaac agcttcagaa gaggtaagaa ctgatataat aaatttactg tgtttagaaa
    16561 atccagatta ttatataact ggatttgata gagagaattt atcaataaat atagtaaaat
    16621 catctagtaa aaataagtat attttagatt atattcaaaa tcataaaaat gagtctggaa
    16681 ttatatatgt tgcaactaga aaggaagttg aaaatatata taatggttta tctaagagaa
    16741 atatatctgt atcaaaatat catgcaggtt tatctaaaaa tgaaagaagt aaaaatcaag
    16801 aagattttat aaatgataat gtggatataa tggtagcaac aaatgcattt ggaatgggta
    16861 ttgataaacc taatataaga tgggttatac attacaatat gcctcaaagt atagaaaact
    16921 actatcaaga aataggtaga gctggtaggg atggagaaaa aagtgagtgt gtacttttat
    16981 tttctccagg agatgtacat atacaaaaat atttaattga tattggagtt gaaaatcctg
    17041 aaagaaaatt atttcagcat aagaagcttc aatacatgat tgacttagtt tacagtaatt
    17101 catgctatag aaagacaata ttgagttatt ttggagaaaa ttatatagac aattgcaata
    17161 attgtagcaa ttgtttagta gagggtgaaa tagtagataa aactatagat gcacaaaaag
    17221 tcatttcatg tgtagctaga atgaaaagaa gttatggtgt tactactatt gtagatgtgc
    17281 ttagaggttc taagaataaa aagattttac agcttggatt aaatactttg tctacatata
    17341 acattatgag agattattct agtgaagact taaagaattt tgtaaataca ttggtttctc
    17401 atggtttttt agatttagtt gagactctag gcaatggaaa tagaggtagt tttcctacta
    17461 taagattaaa tgagatgtct atgaaagttt taaaaggtga agtgaaagta gagtttaaag
    17521 aaattgttat gacaaaatca ttggaagtag aggatgagtt atataatgct ttaagagaac
    17581 ttagacattc aattgcaagt gaagaaagga tagctccata tatggtattt ggagatggta
    17641 cacttagagc catgtctagt agttatccaa ttaataaaga agaaatgcta gatatctctg
    17701 gagtaggaga aattaaatac caaaaatatg gtagagattt tgaagcagta attaaagaat
    17761 atgtcgaaaa aaataatata aataaaaaaa tagatgaaaa aaatgtcgat tcaaagaacg
    17821 ttaatagtga tttcttagag gttaatacag ataaagtttt atatgaaaaa ctgttagtca
    17881 ttagagaaga atatgcaaca aaggaaaaat tacctgcata tatgatttta gccaataagg
    17941 ctttgaaaga aataagtgga agatatccac ttgatgaaga acaattaaaa gatatttctg
    18001 gcataggtgg agtaaaattt gaaaaatatg gagctagtat tttggcagag gttaataaat
    18061 atgtaaaaga aaataatatt aatgttattt gggagaaaaa gggcaaaagg aagttaatat
    18121 tagatggaga aagtagaaaa aataatgaaa tagcattaga tttgctaaat caaggaaaag
    18181 atatacaaag tatcagtcaa gaaatagaag tttcactgtc aaccattatt ggatatgtgc
    18241 atgactatgt aaaggatgga catagtatat catttgaatt aggactagaa aatttttata
    18301 atgaagataa aaagaagatg attttagaag tttgcgaaaa agttggctat gataatttaa
    18361 ataacataaa aagaaaactt ccagattcaa taaagtatga aaatataaga gctgtgatac
    18421 ttgactctta tcttgaaaac ttaaaaaata atattatagc agagtaattt ttaacttaat
    18481 aaaaaataaa atttgtatta ttgtgttgaa ctaataattt tgctgtgtta tactgaattt
    18541 gtaaaaataa tgaaaaatta gagctagggg cgctagaatt ggctagctga gagataaagc
    18601 cgtaacttac aaaccctaat aacctgatca agataatgct tgcgaaggga agctttttaa
    18661 tataatttta ttatataaat aggcaaatta ttcaatgtta ggagaaattt gtctaagtgt
    18721 atatacgatt ataagagtgc tttccaaacg aggaaaagca ctttttttat tttcaaaaac
    18781 tataacttta atcttggagg attgtaatat gaactataca acacaaatgg atgctgctag
    18841 aaaaggcata ataactaaag aaatggaaat cgtttctcaa aaagaacagg tagatgtaaa
    18901 tgaattaaga gaattaatag caaatggaca agttgttata ccagctaata aaaatcataa
    18961 atctttaagt gcagaaggtg taggtaaaaa tttaagaaca aaaataaatg taaatctagg
    19021 aatttcaaga gattgtaagg atatagaaaa agaacttgaa aaagttagag tagcaataga
    19081 catgaaagct gaagctataa tggatttaag taattatggc aaaactagag aatttagaga
    19141 aaaggttgtt gaaatgtcac ctgcaatgat aggttcagta cctatgtatg atgcagtagg
    19201 atatttggaa aaagaattaa aagatataac agaagaagag tttttaaatg taataagaca
    19261 acatgctatt gatggagtag actttattac tatacatgca ggtcttacaa gaagtgtttg
    19321 ccaaaaaata aaaaatcatg agagattgac tcatatagta tctcgtggag gttctttatt
    19381 gtttgcatgg atggaattaa ataataagga aaatcctatt tatactaatt ttgataaaat
    19441 attggatata tgtgaagaat atgatgttac attgagttta ggagatgctt gtagaccagg
    19501 ttgtataaaa gattctactg atggtgttca aattcaagaa cttgtagtat taggtgaact
    19561 tactaaaaga gcatgggaaa gaaatgtaca agtaatgata gaaggtcctg gacacatggc
    19621 tattgatgaa atagaagcaa atgtagtatt agaaaagaga ttatgccatg gagcaccttt
    19681 ttatgttctt ggaccattgg ttacagatat agcaccaggt tatgaccata taacaagtgc
    19741 aataggagga gctttagcat gtgctaaagg agtagatttt ttatgttatg taactccagc
    19801 agaacattta agattgccta atttagatga tatgaaagag ggtataatag ctgcaaagat
    19861 agctgctcat gcaggagata tagctaaaaa tgttaaaggt gctcgtgaat gggataataa
    19921 gatgagtaaa gctagagctg atttagactg gtgtgagatg tttagacttg caatagaccc
    19981 tgaaaaagct aagagataca gagatgaatc aactcctact catgaggata gttgtactat
    20041 gtgtggaaaa atgtgctcaa tgagaacagt taagaaaata ttaaacaatg aggaacttaa
    20101 tctaatataa tttttggcta gtatgactgg aataaaaata agctgaaaag aggaggtgat
    20161 ttagtgaagg ttaatgggaa ggaaattgaa tttgaaaaag atttgactgt tatagattta
    20221 ttaaataaat ataatttaaa aagtgataga gttgtagttg aagtgaattt agagataatt
    20281 gaagaatcta actacaatac atatgtatta aaagacgagg acattgtaga gcttattagc
    20341 tttattggag gtggttaaaa taaaaatatt tgtaaatgaa ttattaacag atgttgagga
    20401 aaatacaact gcttataaag ttagagatag ctataacaat aaatgtgatg tattggtgtt
    20461 aaatggatat ccaattaaaa cagatatgac cctttgtgaa aatgataaat taacacttat
    20521 acaaaaagga gttaagccat cacttgatga attggaaagc ttgttgattg ctagacatac
    20581 tccaaatata cataataaat taaaaaaagg gaaagttgct atattgggat tggggggact
    20641 tggttccaat atagctatct ctttagctag aataggagtg ggagaacttt tacttataga
    20701 ttatgatgtt gtagaaccat ctaatttaaa tagacagcag tattttatag atgatatagg
    20761 aaaactaaaa actgatgcca tgatagaaaa tataaaaaaa ataaatccat ttataaaatt
    20821 aaataaacga gatatttttt taaacaagaa caatatggat actattaagg attcagattt
    20881 aataattgag gcctttgatg atgcttcatg taaagcacag gtatgtaatt atgtattaat
    20941 aaatttaaaa gataaatatt taatagcatc atctggtatg gcaggttact atgattcaaa
    21001 tataataact actaagaaga taaaagacag gttttatata tgtggggatt ttgtgaatga
    21061 agctaaattt ggtgaagggc ttatggctcc aagggttgcc atctgcgcaa atcatatggc
    21121 aaatttggca acgcaaatac ttatagatat gtaaatatta aaattagata taaaaaagat
    21181 tgaatattaa aaaaatttaa cgtggaggga aataatatgg ataaattggt acttggtgga
    21241 catgaattta atagcagatt attggttgga acaggtaaat atggttcaaa taatatattg
    21301 cctgaggtaa taaaagaaag tggaagtgaa ataataacaa tggcacttag aagagtggat
    21361 ttagacaata aacaagaaaa catattaacg tatattccaa aagagatgac aatacttcca
    21421 aatacatcag gagctactaa tgcagaagaa gctgtaagaa tagctagaat atctagaaaa
    21481 atgggatgtg gagattttat aaaaatagaa gtaatatcag atactagata tttacttcct
    21541 gataatgaag aaactataaa agctacaaag atacttgctg atgaggggtt tatagttctt
    21601 ccatatatga caccagacct ttatgctgga agaagactta tagaagctaa tgcagcggca
    21661 gttatgccac ttggagctcc aattggttca aatagaggtc ttcaaatgaa agaaatgata
    21721 agaataatga tagatgagtt ggatatacca ataatagtag atgcaggtat tggaaaacca
    21781 tctcaagcta tggaggctat ggaaatggga gctgatgcag tacttgtcaa cactgctata
    21841 gcttcagcag gagaccctgt acaaatggct agagcattta aattagctgt agaaggtgga
    21901 agagaagcat atattgcaaa aacaggaaat gtgtcagaat ttgcaaatgc atcttctcct
    21961 ttaacaggtt ttttaggcaa tttatagaaa gtggtgattg gtgatgagtt tttatgatgt
    22021 aatagaaaaa tatagggatt ttgattttga tggatattta aataatgtta ctgataatga
    22081 tgttttaaga agtttatcaa aagacaagct tgaagatttt gatatattaa atttgctttc
    22141 taaaactgca gtaaaacatt tagaagatat ggcacaaaaa gcacataaat taagtgttca
    22201 atactttggt aaaacagtat gtttatatac accaatgtat atagcaaatt attgtgttaa
    22261 tcaatgtgtt tattgtagct ataatataaa gagtggaata aaaagaaaaa aattaactat
    22321 ggatgaaatt agagaagagg gagaagcaat ttcaaaagaa ggtttcaaac atctacttgt
    22381 tttgactgga gaaagtagtt ttcactcaag tgtagaatat ataggtgagg ctatagaaat
    22441 attaagagag aaatttccct ctataggtat agaagtttat ccaatggaag tagaagaata
    22501 taagtacatt gtagataaag gtgttgaagg attaacagta tatcaagaaa cttatgacga
    22561 ggaaatatat aagagagtac atataaaagg cccaaaatca aattataaat ttagactaga
    22621 tgctcctgaa agaggggcaa aagcaggtat gaggacttta tcaataggtg cacttttagg
    22681 gctaaatgat tttagaaaag aaactttttt tacaatattg catgggaaat acttaaaaac
    22741 gaaatatcct catattgagc tttcatattc aacaccaaga atgagacctt ttaaagggtg
    22801 ttttgaggaa ttggtagata taagtgatac tgatttagtt caagctatgg tatgtatgag
    22861 attatttgac cctcatgcag ctataaatat atccactaga gaaaatttag aaatgagaag
    22921 tcatataata cctttaggag taactaaatt gagtgcaggt gtatctactg atgtaggagg
    22981 tcattctcaa gatgaacatg atactgctca atttaagata aatgatgaaa gtactgttaa
    23041 agatgtggag aaaatgctaa actcaattgg ttatcagcat gtgtttaaag attgggaaag
    23101 attttaaatg tatctgataa caaacagaaa attatgtagt gaggaacgat atttagaagt
    23161 tattaaagag tctatattga gtggtgtaga aaatataata ataagagaaa aggatttaga
    23221 atatcaagag ctaagaaaat tatatatgaa aataaaaact aaaatcaatt gtatagattt
    23281 tcaagagcaa atatcagatg aaagtttgaa aactaatata aatcaaaaag agtgtagaaa
    23341 taaattcaag gttaatttta taataaatag taacattgaa ttttttgaaa aagtggattg
    23401 tcaaggtatc catcttcctt ttaaattatt cttgaattta attgaaaata agtataattt
    23461 taatgaaaat aaaatactag gattatcttt acataaagta gaggaagtag attatttaga
    23521 aaaattaata agaaatcaaa atataaaaat agattacata acattatcac atatatatga
    23581 aactaaatgt aaagaaggat taaatccaaa aggaattgag cttttaaaag aagctaaaaa
    23641 gattactgat attaaaataa ttgcacttgg gggaatttta ccatctaatg tcaaggaaac
    23701 attaaaatac tgtgatgatt ttgctataat gtcaactata atgaggtcta aagatattaa
    23761 aaaaaccata tcaaattata atgaaaagtt gaattagtaa atatagtata ttgaattttt
    23821 aacttaaata aaaataaaaa agttatcttt taaattttaa aaggtagctt ttttatttta
    23881 tatctttgct aataaaaaat tgtaaaaagg gaaaacttta gtcagagaga ttaaacaata
    23941 tcctagaaag atttaaaatt tagtaaagta tggaggacat tataatgact gacagtaaaa
    24001 agaaacgatt tattatacca cacactttta caataatatt tttactaata gtcttgatgg
    24061 caatattgac ttggatagta ccaagtggtg aatttagtag agaagatgta gaaggtagaa
    24121 tggtagttgt accagggact tatcaaagtg tagaaagtaa tcctcaagga tttgcagatg
    24181 tttttaaagc accaatagaa ggctttatcg attcagctga agttgtaggt tttgttttaa
    24241 tagttggagg tgcttttggt attgtaaata ggactggagc tatagaagca ggaatagctt
    24301 cggttatctc taagtttaag ggaaaagaac ttcttataat tccaatatca atgattttat
    24361 ttggacttgg aggtacaaca tttgggatgg cagaagagac attaccattt tatatgatat
    24421 ttgttccact catgacatcc ttgggatatg attctctaac agcaatagca attgtattta
    24481 taggagcagc agcaggagcc gccgcttcaa caataaatcc attttcagtt ggtattgcac
    24541 aggcactagc tcaacttgct cctggttcag gagtaactta cagagtagtt atttttatag
    24601 catatatact aataagtata gcatttgtta tgtactatgc taagaaggta aaggaaaatc
    24661 ctgaaagttc aatagtatat gaaatagata aaaataataa atcaatactt aatcaaactt
    24721 caacagaaat aaaagaattt acttttaaag aagtatctgt tcttgctata tttggaatag
    24781 ggatggcaat aatgatttgg ggtgttttaa gtcaaggatg gtacattcca gaaatatcaa
    24841 tgtgttttgc tgcaataggt gtgctttctg gattggttgg tagattatct caaattgaaa
    24901 tctcagaaag ttttatagat ggagcaaaag atttagcatc tgcagctctt gctatagctt
    24961 tggctcgtgg aatcgtaata attgctcaaa atggatttat aatagatact atattaaatt
    25021 ccgcagcagc ctttctaggt gggcttccaa aggttatatt tgtatattta tcatttttct
    25081 tggaagctgc attggcattt ttaattccat catcttcagg tcttgcttca cttacagtac
    25141 ctgtacttgc tcctcttggt gatttggtta atatatcggc tcaagtgata gtaaccgctt
    25201 atcaatttgg tgtgggtctt acaaacttta taactccaac ttcaggagta ctgatgggag
    25261 cacttgcagt agcccatatt ccattttcaa aatgggtaag atttataatg cctatcttgt
    25321 tgattttgac agctgtatct ctagtctttt taacaatagg tatttatata gggttttaat
    25381 taagtgtagt tttatttaag atatttagta atggtataaa atgataatat gttttcaata
    25441 aattgccact aatttaatta gtggtaattt gttttttgta tttaaaaata aatatattta
    25501 cttgtatttt gaattaatat ctacttagac attgttttaa ttgttatatt ttcatttaat
    25561 taagcattga tttatcattt tttatatttc atataacaat gcaaaaaata atttttatat
    25621 agtaaatgac aaaagtttac aataaatgta tattttctta ctcattcctt aaaattactc
    25681 atttagttta ataactctca tttcatatgt aaagttggta aaaaaattaa aattaaaagt
    25741 aaaaaactaa ataaattaat gttaatttga aatatatatg aaggtttttg gagaatactt
    25801 acttatgata ggaaaaaatg ttaaaataat agtgtaatca aatataaagg actgaaataa
    25861 ttaacagtta ttaaatatta ggagtgtaaa aatttatggg attaaaagaa tttgatttta
    25921 ttgaagagtc tattgatatg ttgaggacaa tgtcaccaac attagaaact atatcagatg
    25981 aaatagaaga gtattttgaa aatatcttgg atgaaaagaa tcaagaatat ataaatgtaa
    26041 cctctagaat aaaatcagaa tcaagtttaa gagaaaagat aattagaaat agatatttaa
    26101 aaaaatatgg agaagcaagt aatcttattc ataatgtttc tgacttaata ggcctaagaa
    26161 ttgagtgtag atttattgag gatgaaaaca aaatatatag acttttgaga agatatttta
    26221 ataaaacaga tgacaaaata aactattata ataaagagaa taagaatatt aaattaaaac
    26281 tatctgagag acaacccaat aagcaaaaaa atggatttga aatatataaa atagatggag
    26341 tttttgcgta tttagataga gaagtaaaat ttgaacttca aattaaatct cttgtaaatg
    26401 tgttttggag tgaaatagaa cataaaataa tttataaaaa caatacatat ttacttgctg
    26461 ataaatttat aaaggatatg atggactcta taaagaataa tcttactatg atagataatc
    26521 agcttttaag tatttataaa aactttcatt cagggaagtc ttttaatatg aaagtaagta
    26581 aaaaagaaat tgaaaaatta tttgcgaaac tagtctatga cgctttttct gaaaagatga
    26641 ataaaagtat aggttttgtt gtagatttta aaaaaccatg tgagactata ttgaactatt
    26701 cttttaataa acaagatata agtgatgaag ttttaggtaa ttttatgctt gatgagtttg
    26761 caagattaaa tgaaattgta aacaaggata tagattttaa tgagcaaata gaatttgaaa
    26821 gagaaccaac atttgatgat aagttttgta aagacctagg aaatcatttt agaagtagat
    26881 taaacacaga atttccatgg aacctatttt ttagaatatt atttgaaata gagccatata
    26941 acaataccaa agactttgaa aactttgtag agtttataaa agaaaatgtg ctactagaag
    27001 aaaataggga gcaattatta tgccaatttg aagaagatag caaacttata attgaagata
    27061 tatatgattg tatatttaat agtataagtg agattgatag tgttgaaatt ttatataact
    27121 ataatcttga aaaaataaac tttacatcaa gtgaaatcat aaattgtata tgtagagaat
    27181 atgagtgtta tggtgaatac ttagaagaaa aagaaaagct tatgaataca tttaaagaaa
    27241 agattattca aatctttgag taataggtca atgctgaagt ggcgctaatg cgccattttt
    27301 caaatatata tgaattaagt aaaattattt tggaggaggc gatttgtata gagaaaacag
    27361 gtgtaatttt ggcaggggga agaaattcta gaatgggtag agataaagcc tttttagagt
    27421 tacatgataa gctttttatt gaaattgcaa tagaagcatt taaaaacttt gatgagttga
    27481 taataatatc taataatgaa gaattatatt ctaaatacga tattaaagtt tataatgata
    27541 tagtaaaaga tgttggtcca attggaggaa tatatactgc tcttgaatat gcaaagtatg
    27601 atatagttac aattgcatgt gatatgccat atctaaataa tcaaatagtc gaaagaatag
    27661 ctaataaaat gaatgataaa agtgtgattt cagtgacaaa tggaaagtta caaccattgt
    27721 gttctggata taaaaagagt ataataaata aagtatcttt atgtataagg gaaaatgatt
    27781 taaagctcag aagctttata gataaaatag ataaaagtta tatatacttt gatgaagaag
    27841 atttattttt aaatgtaaac actgttgatg agtatgaaaa attaactaaa gtttaattag
    27901 ctatggttgt aaaatagagt aggatttata tggaggagag tttatgaatt tacttaaatg
    27961 cgattcttgg gcagtaatat taaataatag cgataaagaa agtaaagcat ataaaatatt
    28021 agatgaactt aaaaggaata tgtacaaagt tgttgctata gatgaagaga aaaaacctat
    28081 tgaaggaata gatgtgtatg aatgtttaaa agatgttcca cacaatattg atgttgtagc
    28141 tattattgat aaacaatcta agatggatgt gattttagaa gaagtagagc ttttggatat
    28201 acaaaatatg tggtttgaaa aaggaagctt tagtgaaatg atgattaaaa agactaaaga
    28261 tttaaaatta aatatagaat ataatttaag tttatatgat gagttgacta gataaaatta
    28321 tatatcttaa taataaaaat ataattagtt aataaaacat attattttat agtatagatt
    28381 ggttaataaa agtacagatt ggttaatgaa acattaaatt acaatatttg ttaaaaaaat
    28441 tgtgagttac atgatataat gtattaaata ggatactaag gagttgatat attatgttaa
    28501 tagtaactac agaaaaagta gaaggtaaaa agatatcaaa ggttttagga ttagtgagag
    28561 gaagtacaat aagagcaaaa catgttggaa aagatatagg agcaagtttt aagaatcttg
    28621 ttggaggaga acttactgga tataatgaaa tgctcactga agcaagacaa attgccatag
    28681 gtagaatggt tgaagatgca gaagctaaag gtgcaaacgc agtaatagca tttagactgt
    28741 cttcagcttc agttatgcaa ggggcagcag aaatgcttgc ttatggaaca gcagttgttt
    28801 tagaagatga taatagtatt cttgaaaaat aaaatataaa tagttaaaaa gaggcatctt
    28861 ttaaaaattt tatggatgcc tttttttatt tgaaaaaact aatttgagaa gaaattttaa
    28921 ctattatgac aataaaatta gggtgatatt atataaataa gtaaaattat attatataat
    28981 gtatggtata gactttaaaa attttatttg tagagaaaaa tatggacaat gttataataa
    29041 ttatagaaat taaaagtact tacattcatt atgtatgtga catgtataat tagttttata
    29101 tttaatacag ttttgaagta atatcttcat tttgagaacg ttggaataat aaaaaatgta
    29161 ttattatagg tgatataaat aaaaaataaa tataatatgt tatattgctg atagaaaaga
    29221 gaataaaaga aaataggttt tattaaaaga gatttttatt tataggactt aatcaatgta
    29281 tagaggggtg agaacatatg tttaatgttg caattataac acttagtgat aaaggatatg
    29341 aaggaaaaag agaagatata acaggaaaaa agttaactga atttgttgaa aatacaggag
    29401 cttataaagt tactgaatat gtacttataa aagatgataa ggaaatgcta aaggaaaata
    29461 ttataagact ttgtaatagt aataaaatag atttaattct tacaaatgga ggtactggtt
    29521 tttcaaaaag agatataacc ccagaagcaa ctaaggaagt gttggaaaaa gaaataccag
    29581 gtctgagcga atatatgaga atgaaatcca cagaaattac taaaaaggcc atactaagta
    29641 ggggtgtaag tggaataaga aataattcta taataataaa tttacctgga agtcctaaag
    29701 gtgcagttga aaatctaagt tttataattg atgttttaga ccatggcata gaagttttaa
    29761 gaggagaagc tacagaatgt gccactaaaa aaagtgaata gtatataatc tagatagata
    29821 aaaaatagac aaagaggtag ataaagtatg attgataagt atggaagaaa aatagactac
    29881 cttcgtattt cacttacaga taagtgtaat ttaaggtgtg tttattgtat gccaccagat
    29941 gtaaaatttg ataaaaatta tataaatgaa aatctaagct ttgaagacta caagtttatt
    30001 ataaaggcta tggctgaaca aggtataaca aaaattagat ttactggagg agaacctctt
    30061 ttatatccta aattaaatga gcttataaaa tttacaaaag aagaatgtgg aataaataac
    30121 ataggaatga ccactaatgc tattgggctt tctgatagaa tctttgagct tgaaaaatgt
    30181 ggcttaaata aagttaatat aagtttagat tctttgaagg aatataagta taaatccgta
    30241 acaagaggag gaaacttaaa agatgtctta aaatcgattg aatcttgttt aaacttaggt
    30301 ataaaagtaa agttaaattg cgttgctata agtgggttta atgatgatga gcttaaagat
    30361 tttatgtttt taacagttaa atcaccaatt gatgtaagat ttatagagct tatgccatta
    30421 ggtgaggcta atagagttta taagaagggt tattttaatg taaaagaaat gattgaaaaa
    30481 atatatggtt tatataaagt caaaaatgat gaaaaaagta cagcagaata ttatatgttt
    30541 aaaggagcta aaggaagaat aggaattata actccattaa gctgttcatt ttgtaacact
    30601 tgtaatcgta ttagacttac ttctagtggt gcaataaaat tatgtctaca ttcaaaagaa
    30661 gaaatagata taaaaccatt tttacataaa ccattgttat ttagagaatc tatgaaagat
    30721 ataataaaac aaaaaccaga aaaacatcat ttaatagaaa ataaatgtag tgatacaaat
    30781 aggcgtatgt atgaaattgg aggataagta atgttaacac atataaatga aaaagggtat
    30841 gccaagatgg tggacataag tgaaaaagat gatactaaaa gaacggccgt agctacagct
    30901 acaattactc ttagtaagga agcattagaa aaagtaaaaa atggtcagat aaaaaaagga
    30961 gacgtattgt ctgtagctca agttgcaggt ataatgggag ctaaaaatac atcttcaaac
    31021 ataccaatgt gccatcagat taaattagtt ggatgtgatt tagaatttga tgtagatgat
    31081 tctatgtctg ctattaagat atacgcaacc tgtaaatctc ttgggaaaac tggagtagaa
    31141 atggaagctt taaatgcatg ttctttagca gcacttacaa tttatgatat gtgtaaagca
    31201 gttgataaaa aaatggttat aagtaatatc catcttgtag agaagactgg tggaaaatca
    31261 ggagatttta agttcgagta aattaataat atattgggtt aaaatttgga ggaaatatgg
    31321 cgaaggtagt gtcaataaat ataagtgaga aaaaaggtgt aattaaagtt cctgtacaat
    31381 gtgcagagct aaaaataaat catgggatag ttggagatgc acatgcagga aactggcatc
    31441 gtcagataag cttacttgga aaagaaagca tagataaaat gaaaatgaaa ggctttgacc
    31501 aattaaaata tggagatttt gctgaaaatg taactacaga agggatagaa gttttttccc
    31561 tgcctgttgg tacaaagtta agaatagggc aatgtgaagt tgaagtaact caaataggga
    31621 aaaaatgtca caatggatgc gaaattaaga aattgacagg tgactgtgtg atgccacgag
    31681 aaggaatttt tgtaaaggtt ctaaaagaag gaattataaa tgtgaatgat tcaatagatg
    31741 taatctaatg aagtcactat taaaatataa ttataagtaa atactattaa gatttaaata
    31801 tatattttaa gagagaatta attttaataa aatattttag ttataaattg gaatattggt
    31861 tatataaagc tatgaatgta aaatcatagc tttttgtttt tgaattttaa aatataatat
    31921 tttatttata tatattaaat tatattttat ataaaatcaa ttgtttaaat atatattatt
    31981 tatactgtaa atttatagat aataaagtat aaaaaaaata tattttgatg aaatttaaaa
    32041 aaatacatta tataaatata gtaatagtat gaaaatttac atataaaact aaaaaatgca
    32101 agtaattgac tttttaagtt gacaaaatat tgcatatata ttatgatata aatcataaat
    32161 taactacaaa tcaatattat atattcgtag aagaagaaag tagcataaag gaattttaca
    32221 gagagttaga tttggctgag aactaatatt ggaatttatg tgaaaaggac tttggagaat
    32281 actattgtaa ttatgttaga atagtggttt aattcgcctt aagaaaatga gtgagtaaaa
    32341 ttaattttta ctaataagag tggtaacacg gatttatatt cgtctcttgg atttttccaa
    32401 gaggcgtttt ttattataaa cttatttcag aaaatttaaa actatatatt aaatgaaaat
    32461 tataaaaata tgatagttaa taaatttata aattagaaaa ttgtaaaata tgctaaggtc
    32521 agtagtttta cgatttaaat ggagggatga aaatggaaga agaaaaaatt aactatgctc
    32581 tggaacagat tccagagaat caaaaacgtg gttgggtagc tatgttttca gttttagtag
    32641 caataggtgt ggatttatca tctgttattt taggcgctga gttggcacag agtatgccaa
    32701 tgaaacaagc aatattgtca gtaattgttg gttcattttt ttctgcaatt ttgtatacta
    32761 catgctcttt ggttggctca tctacaagtt tatctacatc tatgataaca aagtatgtat
    32821 ttggagaagc tggagcaaaa atattttctc tagttatagg ggtttctcta ttaggttggt
    32881 ttggagttca agtaggtttc tttgctcaaa atgcacagat aataataaaa gatatattta
    32941 atttagatgt aagtatgcag attttaagcc taataggtgg tctcttgatg atgagtactg
    33001 caatttatgg atataaggca atggagaagt tgagtgtgta ttcagtacca tttttattag
    33061 ttcttatgat gctaactata ttcttagctt ttagagcaaa tggaatttca gttgatgata
    33121 atatgaaatc tactatgaca tttgcaggtg gagtttctct gtcaatgagt ataataatag
    33181 ttggtgcaat tgtatctcct gatataagtc gttgggctaa aagtagaaga gactgtgctc
    33241 tttcaagctt tttgggaata caatttggaa atgcttttat gataatagtt tcgatagtat
    33301 tagtaaaatg tatgggaact tcagatatta tgagaatttt tattacatta ggaattgcta
    33361 taccaggtat aatagtactt acattagcac aatggactac aaatacaagt aatgtatatt
    33421 cagcatcatt aagtatagct cttgtactta agaaggctcc tgagaaagta ttaactatag
    33481 tccttggtat tatagcaaca ttattggctg tatttggaat atatgaaggt tttataggat
    33541 ttttaaattt acttggaatt gtaattgcac ctgttggtgg tgtatataca gcagaatatt
    33601 acatagtaaa gcaagaactt aaaggctttg ataaaggagt attatataaa ccaatagtta
    33661 aacgttcaat agtgtcttgg ataattggta tattaataac ttacctttca acatatggat
    33721 ttataactct tactactata gcacctttag atggttttat agcagggttt gtagtacaat
    33781 ctattattgg aaaagtgctt tgttcaacaa aaaataagca agaaatagac aaagcagtat
    33841 aaagaaattt gtttataaag tataaaataa attagaaata tgaggagaaa gtaacatgag
    33901 atttttaaca gaagaaagtg tagataaaat agcagttggt gcagcagtgc ttggaactgg
    33961 aggtggaggt gacccatatg taggtaaatt ggttgcaaaa caagccatta aaaagtatgg
    34021 tcctgtaaaa gtaataagtt tagatgaact tgatgatgat gctttggtag ttccagtatc
    34081 tggtatgggt tctcctgtaa ttacaataga aaaattactt tcagaagttg agttaactac
    34141 ccctttagaa ataatggaga aattattaaa tagaaaagtg gatgttataa ttcctataga
    34201 aataggaggg ataaactcac ttatgcctat agcagttgct gctaaaaaag gacttcctat
    34261 cttagatgca gattctatgg gtagagcttt ccctgaagct caaatggtaa ctttttatct
    34321 tgaaggatat gaggcatctc ctgccgtaat gtctgatgaa aaaggtaatt ctgccatcct
    34381 ttatcctgtg gatggaattt ggtcagaaag attagctaga actttaactg tagaaatggg
    34441 aggaagttct tctattagtg actataattt aagtggagct caagttaaaa aagctgctat
    34501 aggtaatact cttacaatag ctgaaactat aggagggttt ttacttgaaa ataaatctga
    34561 ttcaaaaggt gctgttgaga atatactaaa agaattgcgt ggatacaagt tatttgaagg
    34621 aaaagtaatt gatattaaga gagagttgaa aggtggattt actagaggac atgccttttt
    34681 tgctgggatt aatgagtatg atggagagta ttctatatta ttccaaaatg agaatttaat
    34741 tgccaaaaaa ggtgatacac cactttgtat tacaccagat ttaatagcag tattagattt
    34801 agaaactgga tttccaataa ctacagagag aataaaatat ggctctcgtg ttatggtagt
    34861 agcttttcct tgtaatgaaa aatggagaac agaaaaagga attgagacag ttggacctgg
    34921 atactttgga tatgatgtgg aatataaaac agtagaagaa ttacaaggaa aataaaagtt
    34981 taggaggaaa ttttgatgta tcgtgtagga attgacgttg gaggaacaaa tacagatgct
    35041 tgtatactgg atggggaatt aaaagtaatt cattcagtta aggtggcaac tacaaaagat
    35101 gttgaaactg gtgtttacaa tgccttaaaa aaagttatag atgaaagtaa gattgaccat
    35161 tcattaataa aatatgctat gcttggtaca actcattgta caaatgctat tgtagaaaga
    35221 aaaagactta ataatgtggc tatgataaga ataggaaagc cagccactac tgccattctt
    35281 ccatttatag attggccaga agacttaaga gaaaaaatag aattagattc aatattggta
    35341 tctggtggat atgagtttga ttaa
//
LOCUS       DAGQVA010000043        34849 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.043, whole genome shotgun sequence.
ACCESSION   DAGQVA010000043 DAGQVA010000000
VERSION     DAGQVA010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34849
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.043"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(186..842)
                     /locus_tag="MIV85_002200"
     CDS             complement(186..842)
                     /locus_tag="MIV85_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2961532.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(897..1526)
                     /locus_tag="MIV85_002201"
     CDS             complement(897..1526)
                     /locus_tag="MIV85_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBY2961533.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1657..2298)
                     /locus_tag="MIV85_002202"
     CDS             complement(1657..2298)
                     /locus_tag="MIV85_002202"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBY2961534.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2307..2978)
                     /locus_tag="MIV85_002203"
     CDS             complement(2307..2978)
                     /locus_tag="MIV85_002203"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBY2961535.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLSDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2983..3867)
                     /gene="rsgA"
                     /locus_tag="MIV85_002204"
     CDS             complement(2983..3867)
                     /gene="rsgA"
                     /locus_tag="MIV85_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBY2961536.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3965..4702)
                     /locus_tag="MIV85_002205"
     CDS             complement(3965..4702)
                     /locus_tag="MIV85_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBY2961537.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4810..6825)
                     /gene="pknB"
                     /locus_tag="MIV85_002206"
     CDS             complement(4810..6825)
                     /gene="pknB"
                     /locus_tag="MIV85_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBY2961538.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6842..7594)
                     /locus_tag="MIV85_002207"
     CDS             complement(6842..7594)
                     /locus_tag="MIV85_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBY2961539.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7614..8645)
                     /gene="rlmN"
                     /locus_tag="MIV85_002208"
     CDS             complement(7614..8645)
                     /gene="rlmN"
                     /locus_tag="MIV85_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBY2961540.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8653..9978)
                     /gene="rsmB"
                     /locus_tag="MIV85_002209"
     CDS             complement(8653..9978)
                     /gene="rsmB"
                     /locus_tag="MIV85_002209"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBY2961541.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(10040..10741)
                     /locus_tag="MIV85_002210"
     CDS             complement(10040..10741)
                     /locus_tag="MIV85_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBY2961542.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10810..11562)
                     /locus_tag="MIV85_002211"
     CDS             complement(10810..11562)
                     /locus_tag="MIV85_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBY2961543.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTVVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(11572..12501)
                     /locus_tag="MIV85_002212"
     CDS             complement(11572..12501)
                     /locus_tag="MIV85_002212"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBY2961544.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12516..12956)
                     /gene="def"
                     /locus_tag="MIV85_002213"
     CDS             complement(12516..12956)
                     /gene="def"
                     /locus_tag="MIV85_002213"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBY2961545.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12974..15499)
                     /gene="priA"
                     /locus_tag="MIV85_002214"
     CDS             complement(12974..15499)
                     /gene="priA"
                     /locus_tag="MIV85_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBY2961546.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15738..16937)
                     /gene="coaBC"
                     /locus_tag="MIV85_002215"
     CDS             complement(15738..16937)
                     /gene="coaBC"
                     /locus_tag="MIV85_002215"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBY2961547.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16942..17208)
                     /locus_tag="MIV85_002216"
     CDS             complement(16942..17208)
                     /locus_tag="MIV85_002216"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBY2961548.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17211..17828)
                     /gene="gmk"
                     /locus_tag="MIV85_002217"
     CDS             complement(17211..17828)
                     /gene="gmk"
                     /locus_tag="MIV85_002217"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBY2961549.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17858..18739)
                     /locus_tag="MIV85_002218"
     CDS             complement(17858..18739)
                     /locus_tag="MIV85_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBY2961550.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18743..19573)
                     /locus_tag="MIV85_002219"
     CDS             complement(18743..19573)
                     /locus_tag="MIV85_002219"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBY2961551.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(19860..20894)
                     /gene="ltaE"
                     /locus_tag="MIV85_002220"
     CDS             complement(19860..20894)
                     /gene="ltaE"
                     /locus_tag="MIV85_002220"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBY2961552.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21190..22965
                     /locus_tag="MIV85_002221"
     CDS             21190..22965
                     /locus_tag="MIV85_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBY2961553.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDALHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23180..24832)
                     /locus_tag="MIV85_002222"
     CDS             complement(23180..24832)
                     /locus_tag="MIV85_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBY2961554.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(25131..26342)
                     /locus_tag="MIV85_002223"
     CDS             complement(25131..26342)
                     /locus_tag="MIV85_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBY2961555.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26626..27159)
                     /gene="pyrR"
                     /locus_tag="MIV85_002224"
     CDS             complement(26626..27159)
                     /gene="pyrR"
                     /locus_tag="MIV85_002224"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBY2961556.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27519..28466)
                     /locus_tag="MIV85_002225"
     CDS             complement(27519..28466)
                     /locus_tag="MIV85_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBY2961557.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(28435..28881)
                     /gene="lspA"
                     /locus_tag="MIV85_002226"
     CDS             complement(28435..28881)
                     /gene="lspA"
                     /locus_tag="MIV85_002226"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBY2961558.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29191..29970)
                     /locus_tag="MIV85_002227"
     CDS             complement(29191..29970)
                     /locus_tag="MIV85_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBY2961559.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(30025..30507)
                     /locus_tag="MIV85_002228"
     CDS             complement(30025..30507)
                     /locus_tag="MIV85_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBY2961560.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(30773..32194)
                     /locus_tag="MIV85_002229"
     CDS             complement(30773..32194)
                     /locus_tag="MIV85_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBY2961561.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(32340..33110)
                     /locus_tag="MIV85_002230"
     CDS             complement(32340..33110)
                     /locus_tag="MIV85_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961562.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(33115..34317)
                     /locus_tag="MIV85_002231"
     CDS             complement(33115..34317)
                     /locus_tag="MIV85_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBY2961563.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        11113 a         6376 c         3489 g        13871 t
ORIGIN      
        1 ttttctaaag atttaaatat atttaaaatt aatatacaaa aaaaagtagt tcttattgta
       61 ttaattaaat taatgatttg aaatataaaa ttaatatcaa taaaacctac tttttaattt
      121 tttaaatatt tatttttaat ttattttgtt tttaatttac ttcgatttta aaatgtcctt
      181 gacttttatt ttataaatgt acatatttct tctactggtt ttttagatgg actcttcaaa
      241 ttgtcctctg gcactccaag agctaacatt gcacctaaaa aatactctcc cttttcaaaa
      301 ccagtttctg cttctaaaac agcttctatc tcatctgctg catagttttg acttgtcaac
      361 caacaagaac catatccaag ttcaattgct gatagtgtaa agttttcaat tgcagcacct
      421 agactctgca tacctggatt tcttataaat aatttatcta tagtctcctt aggtgcatct
      481 ataagctcta attcataata tcctgatgga ttatatacct ttgtaaaaac taatactaaa
      541 actggagctt ttaagtaaaa tagtgtaaaa tttttaacaa attttctaaa tctattagcc
      601 ttatccactg atactttatc catttctaca agtatttctt gttgcttttt agttatcaca
      661 tctgctatct tttccattaa atcacggcgt tttataacaa caaaatgcca gttttgaata
      721 ttcttgcctg atggtgctgc acctgctgct tttatcattt ttaaaatatc ttcatctgat
      781 acatcttgat ttttaaactt tcttacactt tgtcttttaa aaatagtatc ttgtaattcc
      841 atttttaaat ccccccataa cttttttatt attttaatat aatttttaaa ctcatcttat
      901 tttaatatat catgttctaa caaatcttta aatgaatcta taaaataatc atatacatct
      961 acattcccaa acccatattt ggcatatata aaaggtatac ctacaaactt agcactattt
     1021 gcatcacctt gcgtatcacc aacatagatt ggatttatta atttatttct ttcaattata
     1081 agtttattat tttctccttt atgcaaacca gtattaccag gacattcaaa atctataaaa
     1141 tactgttcta gtttatgtgc ttttaaaaaa gattctatat atccagcttg acaattactt
     1201 actataaata atttatattt tttagatagt aatttaagag tatcttctat atcatcaaat
     1261 aatttagctc cattttcaga taaatagtca cattctttca aagaacattc attcaataaa
     1321 ttcattcttt cttcttcact taaatttgga aataaacgat ttgctatttc ctcaaaagaa
     1381 agccccataa gacttctaaa taaatctttt gtgacactta attctatttc cttatgctca
     1441 cttaaaacat cctgccagac tttgcatact tcttcagttg aatcccacaa tgttccatct
     1501 aaatcaaaaa taatactatc taccacaaaa aatccccctt atgtcaaagt ttattatata
     1561 tttataatta tatactaaaa agcagataca atcataaata tattttactt gattgtatct
     1621 gctctacaat ataaaaccaa ttgtcaaaat caaattttat aaatttctaa ctacaagtac
     1681 acagccttgc tctactttaa tcttacaaga attactcaac ataacatttg atattccaat
     1741 aggtacagag tatttcatat aataattatc gagagggtat tctaagccag taagtgttac
     1801 acccttagca tcaccattta tagctattac agaaatagtg tcccctgggt ttccatacaa
     1861 tgaaatttcc tcattttcaa ctatatacat ctcttcttta tcagaaagta tcctagaata
     1921 tataccatct tcttttaaat aatataatag ctttatattt gcaagagtgt ggtcaatcct
     1981 tccccctaaa gcaccaaaaa aatcaatatg atttgcttta agtgtcttag ctaaaaaaag
     2041 acaaagctct gtatcagtct catctttttt agatggaaat ttttcaaatt taacaccttt
     2101 atttttatag aagtttatct tttcttcttc tactgaatct aaatctccta atatataatc
     2161 tggcattatt tccattttat aagtgtgatt tgcccctcca tctgcacata ttatgcagtc
     2221 ataacattcc ttaattataa tatctcttgt aacttcgtaa tcttcaattt cgccatttaa
     2281 aacaatacag attttcatta ttaaatttaa actaattctt caagagaagc attctttcta
     2341 aataaattaa ctgtttcttg aatgtcatca cttccaaata ttgcagaacc tgctactatt
     2401 acattagctc ctgcttgtac aacttcggct acgtttttag ggcttatacc accatcaact
     2461 tctatatcaa tgtttaatcc ttgactatct ataatagctt ttaactcttt aatcttatct
     2521 aaaacacaag gaataaatga ttgtcctcca aatccagggt taacagacat taataatacc
     2581 atatctaaat cagatagtac atgtttaatc gtatctactg gtgtagctgg attaagtact
     2641 acaccagctt ttattccatg tgattttata ttttgtatag ttctatgtag atgaacacaa
     2701 gcctcctggt gaacagttat tatatcacat cctgctttta caaattcttc aatatactgg
     2761 tctggatttt ctatcataag atgagcatca aataccatat ttatattttc tttctttaaa
     2821 cttttgacta caagtggtcc taatgtaatg tttggtacaa agtgtccatc cattacatcg
     2881 atatgaagat attcacatcc tgcactttct acttttctta catcttctaa taattttgca
     2941 aaatctgctg ataatattga tggtgctaat ttaatcatgt ttctaatacc tcctactatt
     3001 attttgtctt atttcatgta gcagctgtat ataactatca tatctttctt tagatatttc
     3061 tccatttgta acagcttctt ttatagcaca attaggttca ttttcatgaa tacactttga
     3121 accaaactta caatcattaa atttatcaaa ttctataaaa taatctttaa gttcaacttc
     3181 ctctatatct tcaagtgcaa gggaactaaa acctggtgta tctgcaacca ttccaccaaa
     3241 ttctaatttt aaaagttcag cgtgacgagt agtatgtttt ccccttttta ttttatcact
     3301 tacaactcct gtttgaagtt taaaattttc atctatttca tttaataagc ttgattttcc
     3361 aactccagat ggtcctgcaa acactactac attttctttt aattcttctt ttactttatc
     3421 tatatttaac ttagtaatat tgcttacagg aatgacttta taaccactaa gttcatatat
     3481 atttttaaca gtttctaatg tatcattatc atctaaatct gcttttgtaa ggattattac
     3541 agtttctaaa ttttcttttt ctgccaaaac tataaatcta tctaaaagag ataagtttgg
     3601 tttaggattt tttattgcga atactattaa tgctttatct acatttgcaa taggaggtct
     3661 tataagttct gtatctctac tgtcgatttc ttctaagata cccttttttt catcttcatc
     3721 aacaatgctt attttgactc tatcaccaac caaaggtgtt attttctgct ttctaaatat
     3781 ccctctagcc ttacattcat aaataccatt ataagtatct acataataaa atccactaat
     3841 cccctttata atttttcctt ctagcatcaa atgcctccct ttataaaatt tatataaaca
     3901 catactgttt atgagtagta tatcgtgtta ttctttccta tttttatata ataccacatt
     3961 ttttttaaat aacaaatcct ccgtttggac taattacctg accagtgata aaatttgatt
     4021 tgtctgatgc caagaaaata gcacaatttg ctatatcttc tggagttcct agcctcatta
     4081 gaggggtttc ttccacaaga gcgtctatat cttcctcatt atatccagat aacatgtcag
     4141 tattaatgac acctggagct atgctattta ctctaatatt tgatggtcct acttctttag
     4201 ctaatgcctt tgtcatacct attatacctg cttttgttat agaataatgc acttcacaag
     4261 acgcacctga tataccccag attgaagata tattaattat atttcctttt ttttctgata
     4321 tcatgtattt taaagcaact tgtgaacaat aaaagcttcc ttttaaatta atattcatca
     4381 tattatccca atcttcatca gttatatctg taaacaactt atcttgactt acaccagcat
     4441 tgtttacaag tacatccaat cctccaaatt cttttataca ataatctacc atatcctcta
     4501 catcttctct atttgaaata ttagccttaa aaagttttac agaaaaattt ttttcattta
     4561 atatagtgta caactcttta gcttcatttt ctgacttatt aaaatttact aatacattgt
     4621 aaccttcttt tgcaaaagct ttagacatag ctttaccaat ccctctagct cctcctgtaa
     4681 ttaaaactgt tttcttcttc ataaatactt ttctccttat attataacca attcagtatt
     4741 ttatacaaaa caaactgccc tttaaagaaa atattttcta taaaaggaca gctcttattt
     4801 tattaatatt tattctgttt taccaatgtt tgcgccagtt cctgatgaag ttcctccatt
     4861 atctcctgag tttgagcctc ctgaactatc tccattgtct cctgagtttg aacctcctga
     4921 acttcctcca ttgtctcctg agtttgagcc tcctgaactt cctccattat ctcctgagtt
     4981 tgagcctcct gagtttccac cactatttcc tgagtttgaa cctcctgagt tacttccatt
     5041 attgcctgag tttccaccac tatttcctga atttgagcct cctgaatttc caccactgtt
     5101 tcctgagttt gaaccaggtt ctgttggtgt attattctct ggtgttgttg gttttttatc
     5161 tggtactgtt ggagtctgtg tatttgattt ttctgaacct ttgcttacat atagatttac
     5221 ctcatcacct tcctgagctc ttgatgagcc agcacctgga ctctgactta aaactgtacc
     5281 ttctttatat attgagctgt attcatactt aacagttccc acttttaagt tattttcttc
     5341 aataagttgt tttgcattac tcaaagtaag tcccactaca ttaggaacag atgcctgact
     5401 tgaaccttta cttacgacaa catttatagt atcacccttt ttgacatttg tacttccacc
     5461 ttcaggtgtc tgtgatatta tacaattttc atcaacttca ctattatact cttcactttt
     5521 tacactcagg tataatcctt ctttttcaac agcactttga gcttcttcta atgtcatatt
     5581 tacaagatta ggaacagtca aagatttatt gccaaaccct ccagcaaata aaaacttata
     5641 tgctaagaat acttgagcac acaatatcag tatcaaaaca gccgcaatta cttttaatct
     5701 tcttctagat tttgggcttt cctgtttttt cttctttttc ttagttctct tacttggagt
     5761 actcttaggt ctctgattct ttttagctct cattatctct tcctcttctt catcttcatc
     5821 atcatcttct tcataaaaat catcatagta atcttcatca tcatccaaat cagctacttc
     5881 aacaggctta accacttttt caggagctgg ttttgcaagt gttggattta caactttatt
     5941 aatttctttt tcatcaattt tcttagttgc aaaatcatca tattctttta taaaatctaa
     6001 atcaatattt ttttctatat actctatatc ttctatcaat tcttcagcag tttgatatct
     6061 atctgcacta gatttttctg taagcttttt tattgtagtt cttacacttt gaggaatcct
     6121 aactttttct tctgatgtaa agtctatatc atcattaatg tgttgaagtg ctatagaaat
     6181 tggactatct cccctaaatg gaacttttcc tatcaacatt tcatataaaa ctatacctag
     6241 agaatacagg tcagcattat tagttacaaa tttaccttta gcttgctctg gtgaaaaata
     6301 atgcactgaa cctattatac taccaatatt agtcattgtt gaatttgaaa cagctttggc
     6361 tataccaaaa tcagccactt ttactactct tccttcattt gatatgagaa tattatgagg
     6421 ttttatatct ctatgtataa tccccttttt gtgcgctgca ctaagtgcca tagctatttg
     6481 ttttgttata tctaatgcag tatattcatc taatatacct tcatcttgta taatctcttt
     6541 tagattcttc ccatctacaa actccattac aatgtagtga acttttccat cttcaccaac
     6601 atcataaaca tttactatat ttggatgtga aagacttgct actgcttctg cctctctttt
     6661 aaactttgtt agaaattcat catcatctac aaattcaggt ctaagtactt taagtgcaac
     6721 agtcctgttt aataatctgt ctttagcctc atatacaaat gccattcctc catcaccaat
     6781 cttcctgatg atttcatatc gatttcctaa aattgtatct cccacaatat caccgtccta
     6841 attatacttt tatcactata accgaaacat tatctttacc agaaacatca ttggccatac
     6901 ttatcaattc ttcacttata ttactagttc tctcatattc ataatctaat attaaatctc
     6961 ttatatcttc atcatcaata aacccagtta atccatctgt cgcaagaagt attatatcac
     7021 tttttttgat ttctttctta aaaatatcta caacaaccat atcatctgtt ccaattgctc
     7081 tagttattct attcctctgt ggatgtcttc ttgcctcttc ttctgtaatg acatgggcca
     7141 tcataagttc ttcaaccacg gaatggtcta tagttatttt atcaaatttt tcatctgtta
     7201 acaaataaca tctgctatct ccaacatttg ccacatataa gacattatta tacactatag
     7261 ccgtaactaa tgtagttccc attccttcaa attctatatc ttccatagat tttttgtgca
     7321 caattgagtt tacattatta taagcctgtt ttaatatatc atctatatag tctattttta
     7381 cattatcatg ttgtaataag ttttccttta gaaaatcaat tatattttct actgctaatt
     7441 tactggcgac ttcacctttt ttatgtccac ccattccatc agctatggca aatattccta
     7501 ttggaccatg ttctgtatct ataacttctc cctcacaata gtcttcattg ttttttctta
     7561 tttttcctat atgggaggca caactataaa ccatacgact tcctccttac aaattacttg
     7621 tattttcttc tcaattgccc acaagctcca ctaatatcag aacccataga catcctaact
     7681 gtggcaggta tattgttctt ctccaaacta tccctaaatt tataaataaa tgctttatct
     7741 ggcttttcat attctctttc ttcaacttta tttattggaa ttaaatttac atgacatagc
     7801 atacctttta ggagcttagc taatgccttt gcttcttttt ctgagtcatt tacccctttt
     7861 ataagagaat attcaaatgt aacccttcta tttgtctttt ttatataata tctacatgca
     7921 ttcaatattt cttcaataga ataagcattt gctacaggca taatttttct tcgttcttca
     7981 tcatatggtg aatgaagtga taaagctaaa tttatagcta tttctaagtc tgccaactca
     8041 tacattttag gtactattcc acaagttgaa agagttatat gcctataccc tatattaaga
     8101 ccattttttt cgttaattat ttttaaaaat tgttttgtat tttcaaagtt atcaagtggc
     8161 tcaccactcc ccatcaatac aagatttgat accctcttac cagtatcttc ttgaatttta
     8221 ataacttggt ctaaaatttc ccatggctct aagtttctaa ttaatccatc cattgtagat
     8281 gcacaaaaat tacatcccat cctacaacct acttggttag aaacacagac agtaactcta
     8341 ctatcataat ccatcatcac agtttctatt atatttccat catctaataa aaacaaatat
     8401 ttttttgtat tatctacctt agattctaac tttaattcta tatctatatg ccctatacat
     8461 gaaacctctt ctaatttatt tctcaaactt tttggtatat tgttcatatc atcaaaagtt
     8521 tttgcaccct tatatatcca agagaatatt tgacttcctc taaagggctt ttcatctata
     8581 gttttcataa attctttaag ttcatcttca gtaaaatttt ttaatactat ctttttcttt
     8641 tccattctct cactacctta ttctctttaa ttttgctatg aaaaaaccat ctataccatg
     8701 aatattagga tatatcttta aatatccttt atcttgattg tctaagtcta catttactgt
     8761 atcaattgga acaaattcaa agttgtgatt ttcttcaaca aaagaagtaa ctatatttat
     8821 attctccaca tcttgaattg tacatgtact atatactaaa gttccaccaa ctttgacata
     8881 tttagatgca ttttctaaaa ttttcttttg tatagaagtg atgtctttta actcttcttc
     8941 tttcttatac ttaatttctg gtttacgtct tattatacca aaaccagagc aaggaacatc
     9001 tgctaaaaca taatcaaatt tacttatact attttcatca atctcagaag catcaaatct
     9061 ttctacaaac acatttttaa gccccaatct atttacagta gagtttataa gctttagttt
     9121 atgctcaaaa atatctctag ctactacttg accagtattg ttcattaaag tagctaagtg
     9181 agtagatttc cctccaggag cactacatac atccaaaaca aatgagcctt cttttggatt
     9241 aattactttc cctactatca tagaacttat atcttgaatt gtaaataaac cagccttaaa
     9301 taattcattt ttttctatat ttttcatttt ttcgacttta atagcttctt ctaccatagg
     9361 aacttttaaa catacaatac ccatttcact taatttttca ataagttctt ctctacttat
     9421 tttaagtgta ttcgttctta tatagatact aggcttttca ttatttgctt ccaacaaatc
     9481 ttcagcaaat tcttgtccaa atttatctat ccagtttttt ataatccaag agttatagga
     9541 atactttata gataagtatt ttacactatc ttcctcagtt atgtccatta tagtctcttt
     9601 agctcttatt tcatttctaa gaatagcatt tatgaaacca gaagattttt tatcatattt
     9661 cttagataat tttacagttt cattaactgc tgcataatct gatatactat ctaaaaataa
     9721 aatctgatat gttcccattc ttaaaaagat tttaacataa gttgacattt tttttacctt
     9781 tatttttgaa agtttattga ttatataatc taaataatat ttattttcta ttactccata
     9841 aattaactct gttgcaagtc ctctatccat atcacttatt tctaaatttt taaaatgctt
     9901 atttattgca atatttgaat aattgtcatt tttttctata tcacataata ctttaaatcc
     9961 aacttctctt gcatccatat aaatttctcc cttttattaa acataaaaaa gggttgtttc
    10021 taaacaaccc actttacttt tagtcatttc ttctttgagc tattagtaac aatctaagta
    10081 attgaagtat tgaaaccaat gctgctgcaa catatgttaa agctgctgct gaaagtactc
    10141 ttctactttg tcttgactca ctttcatcta taatacctaa attcccaagt tgaacgattg
    10201 ctctacttga agcattaaat tctacaggca atgttattat ttggaataac actgaagccg
    10261 aaaacaatag tataccaatt tttaaaaatg gaccagccat aataaatcct aaaaatatta
    10321 aaaaccaaga tatacttgaa gcaaaattca ctactggtac taaactactt cttatttgaa
    10381 gaggtgcata acctttagca tgttgtatgg catgaccaca ttcatgtgca gctactgcaa
    10441 cagaagttat agatgttcca taatatacat cttctgacaa ccttacagcc tttcttcttg
    10501 ggtcataatg gtcacttaga tgccctctaa ccatttctat ctttacatca tacaaaccat
    10561 ttgaatcaag tactcttctt gctgtttgct ctccagtata tcctcgacgt gtatttactc
    10621 ttaaatactt atttgttgtt gaactcactt taaattgtgc atatatagta agtaatatag
    10681 ctggaattaa tacaaccatt gttgggtcaa atccccaaaa accgccatat acagggtaca
    10741 taaataacac tctcctaaaa tatattttta ttatacatcc tcttaatatt cacttaactt
    10801 aaaaacagtt taattacaaa ctaatatatt ttttcctgtt aaaaagccta tagctttttc
    10861 aatatccatc atgtctacat tagtatttac acaaggtcca ttaggtcttt tgttaaatac
    10921 acctaaaaca ggaattttct taatatcttg tattccagat gtcaaatctc tttcacatgc
    10981 aacagctaca acagctttag gtttagtgtc cattataatt tttctagcta gagttcctcc
    11041 tgtagctaca aatattttta cattagtttt ttcctttagc ttaattaatt ctcctatgtt
    11101 gcatcttcca cattctttac aattatctat atcattagta acttttaatt tacaactatt
    11161 ctcttgaata caatgaggta ttaaaattat tatatcctct ggattaaaat tatatttatt
    11221 actgtatata tattcattat ttaactttat atatattctt ctaatatcac tttttgacat
    11281 accaaatgat gatgcaatga aagatataat aggaaataat ccactgacaa tattaaaatt
    11341 tattttcatt atatttgagt taacatactt tcctttaatt actctataag taactactgt
    11401 tgaacatagt attataagta ttagtgatat tattataata tttatcatca aggagaatat
    11461 ttgagttaaa cttattataa aaaaattaac aactcctatc aaaattccta atattaaaat
    11521 caaaatccca acacttgtta aatacttctt tatatctgtc atacttttca cctaacccaa
    11581 tactaaacca gtttctatag tattcccttt tatatattca ccaaccaaca ttctcttttt
    11641 attcggcatc tgaatttctt caattaaaag tacattatct atagtactta cttttatccc
    11701 atctttgctt acatcaatta ttgtacctac atcttttgtg cttttttcat ctaacacttt
    11761 agttttccaa actttcatta tgacatcatt ataggtagta taagcacttg gccatggatt
    11821 tactcctcta actaaattgt gtatttctct ggcacttttt gaaaaatcta tgttacctaa
    11881 tgatttattc attattggcg cataggaaaa ttcttcatga ttttgtactt ctcttggagc
    11941 atttccttct tcaattaatc ttaatgtttc ttttaaagtt tctgctccta tattcatcat
    12001 tttatcatga agttctcctg ctgttatatt ttcatcaaga tttacttctg tctttagtat
    12061 catatctcca gtatctaatc cttcatccat atacatagtt gtaacaccag tcttttcttc
    12121 accatttatt attacccaat ttataggtgc cgcacctcta tattttggaa gtaaagaaac
    12181 atgaacattt atacatccaa gtttaggaat ctctaatatt tcttttggaa gtatctgtcc
    12241 aaaagctaca actactatta catctggatt taaagattta attttatcta taaattcttt
    12301 atctctagcc tttactggtt gatatacagg tatattattt tcaattgcca gttcttttac
    12361 tggactcata cctagttttt tacctcttcc ttttggttta tctggttgag ttacaacacc
    12421 caatatttca tacttctcat ctattatttt ttgtaaacat ggaactgcta tatcaggagt
    12481 tcccataaat actattttca tcaaatcaac tcctactact tttctatttt gtcaacaaat
    12541 aaaattccat ctaagtggtc tatctcatga caaaatgctc tagctaaaag ttcttctccc
    12601 tctaactcta ttgtttcacc atttctattt aaagctctga cctttacata atttggtctt
    12661 ctaacatttc ccgcttctcc aacaacactt aaacatcctt cctcatctat ttgctcccca
    12721 gatgtttcta ttatttcagg atttataagt tctataagct cttctccaat atctattact
    12781 actactcttt ttaatattcc aacttgaggt gcagccagtc caacaccatc tgcatcatac
    12841 atagtttctg ccatatcatc taataattgt attatctttt catcaatttt ttcaaccttt
    12901 tttgattttt ttcttaatac tggttctcct atttgaacta tttgtcttaa agccattata
    12961 attcctccta aatttataat acactgtttg gattaatatc tatagataca ttgatattct
    13021 tatcaaatat caaatctcgt tttgttatac atatatattt tattataccc tttaagagat
    13081 taatttcaat attttcatct ttaaagagta tttgccatct ataattttga tttatttttg
    13141 atattgaaca tggatttgga cctaatataa atcctaaatc atttataccc cttttttcta
    13201 ataaataaat caatgatgca tgcatatttt ttatattttt tatcactaat ctttcatctt
    13261 caccactaac aactacactt aacatattat taaaaggaga atatccaaat gcttttctta
    13321 tttttatctc atcttcataa aaaccctcat aatcatattc aatagcatgc ttaatagcat
    13381 agtgttcagt gtcataagtc tgaagtacta cttttccctc tttatcagct ctccctgctc
    13441 ttccagagac ttgagttatc aattgaaatg tagtttcaaa acttttaaag tctggaaaat
    13501 ttaatatcat gtctgcagac aaaataccta ctaaagttac attctcaaaa tccagccctt
    13561 tacttaacat ctgtgttcca ataagtacat ctgcttcttt atctttaaat ttatttagta
    13621 tctcatctaa agcacctttt tttgaagttg tatctttatc cattctcaaa gtttttatat
    13681 ctggaaaaat atattttaat tcctcttcaa ttttttgagt tccaactcca aatggcttaa
    13741 cataagtact tttacattca ggacactctt ttggaatttc tttctcatat ccacaatagt
    13801 ggcatcttcc agtattgctt ttcttatgat aagttaaaga tatatcacaa ttttcacatt
    13861 gaaacacata tccacacttt ctacaagata caaaatttgc ataacctctt ctgtttaaaa
    13921 atagtattac ttgattattt tcttcaatcg cataacgtat ttctttttgt aatttcaaac
    13981 taaatatact tctatttcct ttatctaact catctttcat gtctacaact tcaatgtttg
    14041 gaagaggctt atcatttgct ctacttttta tatttataag tttgtattct ccagattttg
    14101 ccctataata ctcttcaatt gagggcgttg ctgaacctaa aataagagtt atattatttt
    14161 ttaatgccat aaatctagca acttctatag cattaaattt tggattcttc tcagacttat
    14221 atgatgactc atgacattca tcaattatta ttaagcctaa ggaattaaaa ggtgcaaata
    14281 aagctgacct agctccaatt aacactctta ctttacctgc tttgacagct ttgtaaacgt
    14341 catgtttttc tccttcagat agtttactgt ggaacactcc aactaaatct ccaaacctac
    14401 tctttagcct atctattgtt tgaggagtta atgctatctc aggtactaag aatatactgt
    14461 ctaagccttg atttagagca aattctatta tttccatgta aacttcagtt tttccacttc
    14521 cagttactcc atgaattaag tatggttttt tatcatctac aaacatattc gactttatct
    14581 catcaactgc ttcttgttgc tcattgttta attttatact ttttagtacg gatttgtaaa
    14641 tactttttgg ctctctataa taatccttaa attctagggt tattagcttt ttcttactta
    14701 gagaatttat actttgtttt gaagcattta ataaatccaa taaatcattt atctctacat
    14761 tttcattatt tttaagaaaa cttaatatct ctttttgttt acttcccaca tttattttat
    14821 tttgctctat ataatcgtca atcttatcac tttctaaact caaagatata taacatactt
    14881 tcttttcatt tttgtgattt ttatattccc aacataattt tataattcca tttttattca
    14941 ttgtgtacaa agaactattt aagtttggta tatattttaa cttatcaacc ttaattttac
    15001 ctttactatc aatcactttc tctactattt ctctattttt atcacttaaa gttgatattt
    15061 tttccttcaa ttcaatatca tttaatccac ttaaactttc acctaatagg actactttat
    15121 aattatttaa tttgtatccc tttggatata tcaaatttat acattctata taagtacaca
    15181 aatatctatt tttcatccaa taaaccaact ctaaatcttc ttttctaaat atcggatttt
    15241 catctaatat atcaataatt tcttttattt ttattttttc atctaagcta tctgtaaatt
    15301 gaaatacaaa ggcttctgtt ggtttattac cttttccaaa tggtactaat attctgtgcc
    15361 caatttttat tacatcagat aaaaatacag gaatttgata tgtaaataaa ttatctgtat
    15421 atatagtatt acttctaact attacctttg catatttttt cattataaaa cctctactta
    15481 aatttaatat attgttcata ttttaatata ctttacaaga tattaaaatc tcagaattta
    15541 taagcaattt caagttatta atattaactt tattttaata attaactatt aattatattt
    15601 tatactttat gacaaaataa atgctgaaaa ctacaattta actgacattt gcgagttttt
    15661 actcgctaaa attaaattgc agctttcagc cactttagct gtgataaaat acacaaatat
    15721 catatttaaa aaaggtctta tttctcaagc aacgctttaa ctttatctaa aataacattg
    15781 gctacttctt cttttttcat cttaggatac tcagtaatat ttccctctac atctattatt
    15841 tttacaatat tagtatcagc tctaaaacca gcaccttctt tagttaaatc atttgccaca
    15901 ataaaatcta aatttttctt ttttattttt cctttggcat gttctataag gtcattagtt
    15961 tcagctgcaa atccaattag tatcttatct tcttttattt ttcctatttc ataagcaata
    16021 tcataatttc tacttagttc tattgataaa tcatcattct tctttttaat ttttttgtca
    16081 gaataagttt ttggtttata atctgcaact gctgcacttt gaattactat tttattttca
    16141 cttaaatttg atactactgc ttcatacaaa tcttgtgctg actctatttg aacaaatttt
    16201 ttaagatttt gtggaataga aagatttgta ggacctgata ttaatgttac atcagcacct
    16261 ctagctatag cttctcttgc tatagaatat cccattttac cagaagacct attagttaaa
    16321 tatcttactg ggtctatact ctctacagtt ggaccagctg taactatcat actttgacct
    16381 tttaaatctt gctctttagt aagattagtc aaaacttcct ctactattat atctggatta
    16441 gctagtttac ctgttccaat atctccacat gcaagccttc cactttccgg ttcaataaat
    16501 ttatatccaa agctctttaa agtttgtata tttttttgaa caattggatt ttcatacata
    16561 ttagtattca tagctggtgc tataagaacc tgtgcttttg ttgccataac agtagttgtc
    16621 aacatatcgt cagctatacc atttgcaatc ttgcctataa catttgcact tgctggcact
    16681 attaagaata aatctgcttt ttttgctaat gatatatgtt caacttccca agtttttggt
    16741 tcttcaaaca tatcttctac tacataattt tgactcagcg attgaaatgt aagtggttta
    16801 acaaattctg ttgctgattt tgtcattata acatggatat ttgcatttag tttttttaac
    16861 ttacttacaa catcacaagc cttatatgca gctataccgc cacttatgcc aattacaaca
    16921 gttttatctt ttagcatgac cttactcctc ttctgaaatt tgttggtgtt gctcagcatg
    16981 atgtctagct tcttctatct ctatttcctc ttctgtcaat aatctatatg ttatttttcc
    17041 acttgcaact tctttagttg ctacacatac aggcttttcc ttagttttat ttgaaacata
    17101 tggttcttct ccatcaatta attttcttgc tctctttgaa acagtcccca ctaaatagta
    17161 tctgttgtct attttttcta gtacctcatt gatagatggt tttaacataa ttataattcc
    17221 tccttaaatt tctctattat aatattttta tatctgctaa ctttattctt ttcagatgat
    17281 attatacctt ctatttcttt agcagatgtt tttacatctt cattaaatat aaaataatca
    17341 taatccttaa tcattttaat ttcttcatat gcacagctaa atctcttctc tatttcagct
    17401 tctgtttctg tacctcttcc aacaattcta ttttttaatt cttcaagtga tggtggtagt
    17461 acaaatataa atactccctc tgggcaaact tcttttattt gttttgctcc ttgcatttca
    17521 atctccagta atacatcttg tcctttttct aaacattcca ttattgccgc ttttggagtt
    17581 ccataaaaat tatcataaat ttgagcatac tccaaaaact cacctttttc tatcatctct
    17641 tcaaactttt ccttacttat gaagaaataa tttactccat caacttctcc agttctgggt
    17701 tttcttgtag tagctgatac agaaagtttt attgtatcat tttctttaag tagttctttg
    17761 caaatagtac cttttcctgc acctgatggt cctgatacaa ctagcaataa tccttttttc
    17821 acaaacattt aagcattccc cttctaatat tgtattctta ctctatattt tgtatttgtt
    17881 ctcttatttt ttccaattcg ctttttactt ctactactaa attagttata tttatatcag
    17941 atgacttcga acctatagtg ttagtttctc tattcatctc ttgtattaag aaatctattt
    18001 ttctacctat agagtcgtct ttaaatatag tatttttaag ttgccctata tgacttttaa
    18061 atctaactat ttcttctgtt atactgcttt tatctgcata tattgcaact tcttgtgcta
    18121 atctattctc atctattata cttgggtcat ccagtaattc acttattctc aaattcaatt
    18181 tttctctata atcttctaca acactacttg aatatttttc aatctcttct atatgatttt
    18241 ttaataaatc acatctcatg gcaatatctt cagctaattt tttaccttct tcacttctca
    18301 tttctcttaa tttgattaat gcatcttcaa ctgcttgatt caacattgac cacaataaat
    18361 cttcatcttc ttccttttct tctattttca caatatcagg aaactttgca acattcataa
    18421 cgctaatatc atctataata tcaaatttat tttttatttc ttttagtatg tctatatact
    18481 gagatgctaa tccctcatca aaatttaagt ttacatcttc tttgcctaat aagtcaaact
    18541 ttatgtataa atctactctt cctcttttta cataattttt tactaaattt ctaactttat
    18601 cctctaaaaa tgaaattttt cttggaagac gtatgtttat atctgaatac ttatgattta
    18661 tcgttttaca ctctactaaa aagtaataat tatcatcctt gtattctcct cttccaaaac
    18721 cagtcatact tatagccatt aattaaacct ccaaaatacc ttcacatatt tttactgctg
    18781 gacctgtcat ataagagaaa tctcctacat ctattttaac tgttccacct tgagacgtta
    18841 catttacact actttctacc atattaagta aattgcacac tattgctgat gcagtcatac
    18901 cagtaccaca acctaaagta tatccacaac ctctttccca agtataaaca tgtatattat
    18961 acttatcttc tacctttaca aaatttacat tcgttttttc aggaaatatt ttattatttt
    19021 caatctcttt tccatattta caaacatcat ctacatctaa ttcatctact ataactactg
    19081 tatgaggaac ccccatcaac atagaagtaa ctttaagctc cctatctaaa acctttatac
    19141 tttcttgcac aaaacgttct ttatttgtaa gtacaggaac gtccttagct ataaaacttc
    19201 cttttcccat attgactctt atagagttta tttctctatt agtaagattt acttttatat
    19261 cttttatacc atctaatgta tctactgtaa aactttcttt tttaactata caattatcat
    19321 aaacaaattt acaaaaacat ctaaggccat ttccacacat agctgctctt gaaccatcag
    19381 aattataata taccatttct acatctgcaa cttttgaatc tttcacaact aacaatccat
    19441 ccgctcctac agaaaatctt ctatggcata ctttttttgc taaagcagta taatcagatg
    19501 gatttatctg gtcgaatctt ccatctattg ctataaaatc atttcctatt ccatgtagtt
    19561 tccaaaattt cataagtatc gctccttcgt aaattaacgc ttaaactatt ataacataaa
    19621 aaaattccca taaacttata atttatggga aaagttttgt aatgacaact ataatttgag
    19681 gatgtgaggg agagttgcca ttacaattag ggtaattata ttatgttttt aagctagttc
    19741 tttctatgtt tatatattaa tatttctata tgaattttat gtatgtttta tttaaactgt
    19801 ctatgaattt tttaattaaa catctggtaa ctagctataa tccttctagt agatatctat
    19861 taacatacac ctattaattc tttaagtgtt tttaaaacat agtctaaatc ttccttagta
    19921 atatctacat gagttacaaa tctatattca ccattttcca ttttattaat ttttatattt
    19981 ctttcaaaaa attcttttat taaaacatcc tcttttataa tatcttcact catcttaaaa
    20041 aataccatac ttatatctgg attaacattg tttacttcaa tgccatcaat tttatttaat
    20101 tcacaagcta aatattttgc attttcatgg tcttcattca atcttaaagt cattttttca
    20161 atggcaatta taccagctgc tgcaactata cctacttgtc tcattccccc acccataact
    20221 ttttgctttc ttctagcttt tgctataaat tctttatttc cagcaagtat agaacccatt
    20281 ggtgcagcta aaccttttga cacacagaac ataacactat cacaacactt tgctatttct
    20341 ttagcttcta cacccaaagt taatgctgcg ttaaataatc ttgctccatc taaatgtact
    20401 ggtaagttat gtttctcagc tattttttta atttctctta aattatcaag actcacaact
    20461 gttccacctg aatatgcatt ttctacacat ataagccctg tctgtggttc atgtatgtca
    20521 tctcttctaa ttgccttttc aacaagttca ggatttagag ctccactttc gtcttcatct
    20581 atagttctaa gctgaactcc agctattaca gcaggtgccc caacctcatg agtcacaatg
    20641 tgataacctt taccaataat tatttcttgc cctcttaggc aatgagtaaa tagagctaat
    20701 tgattcccaa aagttccact tggaaggaaa atagcatctt cttttccaac tttagctgct
    20761 gctaattctt caagtttatt tacagtaggg tcatctctaa agattgaatc tccaacagga
    20821 gcctttgcca tagcttctct catttcgtca gtaggcatag taacagtatc acttcttaaa
    20881 tcgataaatc tcattttttc aaccttcttt catatttata tactatagaa ccttaaaatt
    20941 gattttttct gtaaagttca tatactttca tagcttatac tctacacaat aattatacta
    21001 tatttacttt atatttaatc tactttaaat tattaatttt aaaaataaag tttcctctct
    21061 aataaatata aataattata caatttaaat attaatctct attgtttaaa ttccccctag
    21121 tcacaaagcg tatattatgt gtataattaa tttactgact cattttggtc aaagaaaggg
    21181 gtgctataaa tggcattaga tggattagtt atacattcaa tagtcgatga attatcatca
    21241 aaacttacag gtggaaaaat agataagata catcaacctg aagatgatga ggtaattttt
    21301 aatataagaa ataataaaga aaattttaga ttggttttaa gtgcaagtgc ctcaaatcct
    21361 agagtttatc ttacaagtaa ttatcaaaaa gaaaaccctc taaaagcgcc tatgttttgt
    21421 atgttactta gaaaatacat acaaggtgga aatatagtag aaatttctca aataggtttt
    21481 gaaagaataa taaaaataag tgttgaatct ttagatgaat taaaagaaaa gacagttaaa
    21541 aatattatga ttgaaattat gggaagacat agcaacataa taataactca tggtgaagaa
    21601 aataaaatta tagattctat aaaaagagtc ccttttagca taagtagagt tcgtcaagtt
    21661 ttacctggtc atgattattc attgccacca gaacaaaaca aactcaaccc tcttgatgat
    21721 atatctaagg atttgtttat taaaaaccta gaggaattgg aaggacctat ctttaagtct
    21781 atatattcta aatttctagg tataagccct attatagcta aagaaatttg ctacagagca
    21841 ggtgtaaatc aaaatgctat cataaaggat atatctgatg aacaatttga tgctttacac
    21901 aaagtatttt gtaatttatt caatgatata aattctaaca aatactctcc ttgcattatt
    21961 atagataaaa aggtggataa ggtagttgat ttcagttgta taaaccttac attatttagc
    22021 gatttatcat atataaataa ggatagtatg tctcgtattc tggaagattt ctatagaact
    22081 aaggatatta aagatagaat taatcaacgt tcatctgatt taaagaagag tatatctgtt
    22141 aagcttgata gactttataa taaacttaaa aaacaagaag aagaattatc agaatccgaa
    22201 aatgcagaca tttataagat aaaaggagaa ttgattactt catatattta tatggtagaa
    22261 aaaggtatgg aaagtattga agttgctaac ttctatgatg aaaattgtaa tgatgtaaca
    22321 atagaattaa ataaaaactt gacaccatct gaaaatgctc aaaaatactt taaaaagtat
    22381 aacaaaatga aacatgctaa agtcgagata tctcatcaaa tttccttaaa taaggaagaa
    22441 atagattact tagaaaacat aattttaagt attgaaaact gtgaaaattt agctgaatta
    22501 caagatataa aagaagaact tgctaaagtt ggatacatca agactcaaaa gaaaaacagt
    22561 aaaaaggata ctatcccatc tacaaaacct catgaatttg tgtcttctga tggatttaaa
    22621 atattggttg gtaaaaacaa taagcaaaat gactatctta cactaagact tgctgataat
    22681 gatgacttat ggatgcatac aaaaaatatt cctggttctc atgtaataat aaagtgtgct
    22741 ggtaaggaag tccctgataa tactgtattt gaaggagcta tgctagcagc attctttagt
    22801 aagtcaaaac tttcttctca ggtgcctgta gactatacta agagaaaaaa tgtgaaaaaa
    22861 cctagtggtt ctaaaccagg tatggttatt tatgaaacta acagtactat ttatgttact
    22921 cctgaagaag aaacagtagc caagcttaag gttaaatctg aataaattct gcactaaata
    22981 caaaataaat gttagacaac tacacattat cattctaaat aaaaatagtg gccttcttat
    23041 aaagtacaat aataaggcca ctttctaatt agcttacttt taattttcta acaaaatact
    23101 tttctgtttt aataactata cttatattcc caacaaatat tttcagtctt cttatataga
    23161 tgtaattaaa aagttaacac taaaagctat tttttaattt attgatttgt tttagtaatt
    23221 cattatattc tgattcatac aattcttttt ttagattatc tttttctata gataacatag
    23281 atataacagt tgtaagtcta ttttctaata ctagaagatt ttcttttttg atttggtttt
    23341 ctctactagg agttttttta tttctgctaa ttgtatattc gtcataatta caatcaaact
    23401 cccttatttt agcatctttt atctctataa tatagttaca aatatgtgat acaaatactc
    23461 tatcatgaga cactataagc atagttttat cagtatttat cagtgccttt tccagtgctt
    23521 ccatagattt tatatctaag taatttgttg gttcatcaaa tactaaaaaa ttattatctt
    23581 ccaatattat tttacatagt gctattttta ccttttctcc accactaagt acttttactt
    23641 ttttgtagac atcatcacct ttaaacccaa ataggcttaa gtttatcctt ataaaagatt
    23701 catcaaatga actattaact ttagtattgt atagaacact cttttcctca tctaataaac
    23761 tttgattttg gtcaaaataa cctactttta ccttgttatt tatttttata ttgtcatttt
    23821 tatcagccaa tatttctttt atcagagtac tttttccaca cccattatca cctaacaatg
    23881 ctatcttttt acctcttttt atcttaaagg aaacattatc taacaggagc ttattttcta
    23941 actttagagt catatctttt acctctacta gatttttgct aattatctcc ataccatctt
    24001 gcatcttaat gttcatttct ttagaaactt taggtttatt ctttacctca agtttatcaa
    24061 ttctgctttt tatagccttc acatttgagt ccaacttttt cttattagtc tgaccaccca
    24121 ttttgtgcaa cctagcttct gaattaccca ttctttttgg tgtttttctt atgccatcac
    24181 ttaaagcttt tttatataaa agagcttttt caagcctttt tttctcttta acatattctt
    24241 gatactcaaa atcagctctt tttacttctt catctttttg cattaaataa tcagtgtaat
    24301 tgcctttgta agcttttagt tttccatctt ctagttctaa tatagttgta cataactcat
    24361 ccagaaaacg tctatcatga gatattaata ataatgctcc ctcatgcctt ttaaacatat
    24421 cttccaaaac cccaatgctt tttttatcta agtttgaagt tggctcatca gctattatga
    24481 tatttttctt attactcagc gcatctgcta tttttaactt aaccttttcc cctcctgata
    24541 agtgttcttc aaatttatct ggagcattta aaagactctt ctccttacta tgactacatg
    24601 tttcaatatt attttcactc tgacttatat aagaatagct ttctgtaagg taagtatatc
    24661 cttcatcaat ttctatttct cccaatattg cttttaataa tgttgttttt ccttgaccat
    24721 ttgaaccaac tagacctatt ttgtcatttt ctaatatttc aagtttatct atatccaaaa
    24781 ttaatttatc tgcataatat ttctttaaat tctctacttt tactaacaac ataaaaaatc
    24841 cctccttaac acacttaaat ataaggagag attctataaa taggcataac aaataaacgt
    24901 atagactata atctactctc cttaatttaa gcattgcaaa taaagccacc aaaataggct
    24961 tttcaaaaat tacaatactt taaattataa aaaatagatt atattctcat tgtcctagtt
    25021 accttgccct ttctttcatt tatttttaat cattatatca acattaatta caaatgtcta
    25081 tagaaaatta actaatttta gttattcaat atacaactta ttctttaaat ttattcttct
    25141 tcaactttaa agtcctgatt atttaaaatt ctgtttaata caattccaac aattgcagct
    25201 aaactaagac cagttatctt tactgtactt gttataggga ttccaacaga aataccttta
    25261 ttagataaat atgttgttcc aagacctatt aataatataa ctgctatgat taatatattt
    25321 attttacttt ctacacaaga actgtccctt atagttttta atcctacata agttatcatc
    25381 gaaaatagca ttatactaat tccacccata actgaacctg gtatactttg aagaaatcca
    25441 ccaaacttgc ctacacatgc aagcaatata gcaaatattg ctgtacgtct aagtattgaa
    25501 gggtcatagt ttttagttat agcaagtact gctgtatttt ctccataagt tgtattggct
    25561 ggtcctccta aacaccctgc aactatagtc gcaaatccat ccccaagtaa tgttctattt
    25621 aatccgggat tttctataaa gtttttacct actacagcac cattagtagt catatctcct
    25681 atatgttcca taaatacagc taatacaact ggagatataa tcactattgc tcctaaactg
    25741 aacttaggaa ctgtaaagtt aggtattgca aataaacttg cttctgtaat agtagttata
    25801 tctactaatc ttaatatcaa acagattata tacccagaaa aaactgctat taatattcct
    25861 aattgtttta taaatcctct accaaactta ttggttaaaa ttgctattgc taaagttata
    25921 aatgctatca caaaattggc tgaagccata ctaaaagctg ttggcaataa atttaatcct
    25981 ataactacta tcatagctcc tgtaacttgt gcaggaaaat ataatttaat tttatttaca
    26041 ccaactactt ttactataat cgacattata atataaatta atcctgctac tattatacca
    26101 ccttgagcat atgctaaatc tccaccatat gcctctttag ctgctagtat aactggtata
    26161 aacgcaaaac ttgaacctaa aaaggcaggt acttttcctt ctgtacaaaa atgaaatatc
    26221 aatgtaccaa caccagcaca gaaaattgca actgacggat taaaacctgt caaaatggga
    26281 actaatactg tcgctccaaa catggctaat agatgttgta aagacattat cgtttttttc
    26341 ataaaaacct ccaaaattat tatatataaa taaatcctct gtttaattaa tatcttttaa
    26401 ttaattatca ttccctagat tctatttttt aacctctata tacttattat ataatttatc
    26461 attattttac attttacgac atcaaaaact caaataaagg agaataaaaa ctacattaag
    26521 actcacatcc ataaaattat aatatttatt ttgtgcaatc tatgtaagct ttatcctcct
    26581 ccctgactat tcaatgctaa gcttttatat aatacttaaa aataattatt ctttgattgt
    26641 aactgaatct tctccatcaa tttctaataa actgacagat ataatttcat gtctagaagt
    26701 aggtacattt tttcctacat aatctgctct tataggcaac tctctatgcc ctctgtccac
    26761 tagcactgct aattgtattg atttaggtct tcctatatct ataatagcat ctagtgaagc
    26821 tctcacagtt cttccagtgt ataaaacatc atcaactaaa actactgtct tatcatttac
    26881 attaaaatct aaataagttc ctttaactac aggttcaaca tgaatttttt ccaaatcatc
    26941 tctatacaaa gttatatcaa tatctcctgt atctactttt gttccttcta tttgttctat
    27001 tttcttagaa attctatttg caattggcac acctctagtc tttattccaa ctaaaactag
    27061 attttctaca cctttatttc tttcaattat ttcatgactt attctagtaa ttgctcttgc
    27121 tattgccttt tcatccatta attgagcttt ttctaccata tcataattat tgtcaaagat
    27181 ataatatatc tatttgacaa atctactcct ttcttttaat tttttataaa tttattttta
    27241 tttaaaattt caatttaaac aacaaaaaaa cttctcatca caagacaaga agctcttata
    27301 taaaaaatat acagtgcaat ttagcaattg tcttacgata tctctgtatc gtttaaagat
    27361 aattttttaa tctatcaaat caaattatat atttatattt caaatttttc aagctttttt
    27421 aaacaaaata ctttaatata agatatttta tttaaatttc actaaattta tttacttata
    27481 taaaaacaaa aaatgattta taagtattat acaaatagtt attttatctt tttaataact
    27541 tccttaaaat actcaggtaa ttctgaatta aattcgatat attccttagt agtaggatgt
    27601 ataaatccca acttcttagc atgcaaagtt tgtcctttta atttaaattt agtttctttt
    27661 ggaccatata cataatcacc taaaagtggg tgatttatag acaaagcatg aactcttatt
    27721 tgatgagttc taccagtttc aagcctagct ctcatatgtg taaacttatc aaatctttct
    27781 acaacttcaa agtgagtgat tgcatttttt ccatctttta ctacagccat ttttaatcta
    27841 tccttaggat ttctccctat aggtttatca acagttattt tatcttcttt aaccacacca
    27901 tagcatataa attcatactc cctagttata gtatgttcct ttaactgttc tgctagaaaa
    27961 ttatgtgcat aattgttctt agctatcata agaagaccag aagtatcttt gtctattcta
    28021 tgaactatac caggtctaat aacgccattt attgatgaca acttatcttt acaatgatat
    28081 aaaatcccgt ttactaacgt attttcatag tttccaggag caggatggac aaccatatcc
    28141 tgaggtttat ttattattaa gacatcatca tcttcatata caatatctat tggaatatct
    28201 tgaggtaaaa cttctaatac tttaggttct ggtatctcta taacaatatt atcttcctct
    28261 ttaaccagat atctagcttt ttctacttta ttattaacct ttacttttcc atcttttata
    28321 attttttgta tataacttct tgacatatca cctaattgtt ctgctagata aatatcaagt
    28381 ctaacttctt cttcctcttc aagtactaaa aactctttta cttcatccat tatatcacct
    28441 acttttactt tcaaaaaata aaacatatat acataaaaac acagttccta caactacaaa
    28501 tacatcagct atattgaata catattccca tataattcta aagtcgaagt aatctactac
    28561 aaaacctaat cgtactctat caattagatt tcccaatgca ccagatataa ttaatataat
    28621 tcccaacctt ccaaatatat gtactttcct tgtattaaga tagtatagtc caaatactgt
    28681 tgcaagtaat gcaacaatta taaatatcca ttgattattt tgtaataatc caaatgctgc
    28741 acctctattt tcgacataag ttaaatgaaa tacattattt attattggta ttgttgatac
    28801 atccaccaaa ttattcaata cccatatttt agacagttgg tctaaaccta tgagtagaat
    28861 tattattaat atatatagca atgatttttc cccctataaa ttatttaaaa accaatttta
    28921 tttgaagcac actattatta ttatacaaaa aaaatgctct aaagagcaac tttattaaaa
    28981 ttgtattttc ttaataaagc tagaacaaaa tttaaaatag tactactttt tttatattgt
    29041 agatttctac atatttaaaa tcatatcatt atgtataaaa aatttaaaaa taccatacta
    29101 atcaatattt tttgtgtatt ttatagatta aagattaatg atgtctgtaa tttaaactta
    29161 caatcaccac taatcttcaa acaaatattt ttacttttgc acttgcttat ttttatctaa
    29221 atgttgtata agttcagata ctgttacgaa tttatatcct ctctctttta atttaggaat
    29281 tactacttct aaagcttgta tagtttgtga tttatcattt cttttagtgt tataatcatg
    29341 taaaagtatt atattaccat tttggacctt tgtaaggata gtatttataa ttgcatctac
    29401 tccagggtta gaccaatctc tagggtctaa gtttgaccaa agaattatat tcatgccttt
    29461 agaaactata atatcacaga cacttttact catggctcta tatggaggtc taaatatctt
    29521 tggttctact cctattacac tttttataat attttgcgta tctgttattt ctttttcaac
    29581 actactataa ctattttttg caacatttat atgtgtaaat gtatgattcc ctatttcatg
    29641 cccctcatca tattgtcttt ttaataattc tttgttatat tctacttttt ctccaactac
    29701 aaaaaaagtt gcttttacat catttttctt taatatatca agtacttgtg gtgtaaaatc
    29761 ctcatctgga ccatcatcaa aagttaatgc taaaattttt tcatcctcat ttcctttttt
    29821 tattattaca tcttcataat cgtcttttat attgtcattt aaactatatg cttcttttga
    29881 actatcttga ttatgtgtat tatgattata tgtatataca cctactatag ataataaaca
    29941 tatacatata ccccatatta ttttcttcat gtcattacct cttttctaat tcattctagc
    30001 aatatatttt ataatgtcag ttttttaatc tctcaatatt ccatttttat ttaaatcagt
    30061 taaatttgtt aggtcttctg aataaaagtt agaatcttct acatcagggt tttgcattgc
    30121 atcacctaat aaattatttt ctttctttgc acaatcatta cataaacttg tatctggcaa
    30181 tatatccaat ctttctaaat ctatttgatt atgacataaa tcacaaatcc catatgttcc
    30241 attctctatt ttagataatg ctaagtctat ttgatacaat cttccctctt catgatttat
    30301 tagactgttt tgcatatttt gcatatataa atctgttccc atgtctccta tatgattatc
    30361 ataactagat aattctcctg atgaatactt ttcacttgta tgtttagttg tatctccaaa
    30421 taaagtatta tctttcatat cctctactaa attagttaaa ttttctcttt ctttcaataa
    30481 tttatcttta tattttttag tatccatttt taacacctct aattttaata tttacatcat
    30541 aaaaatagta tgtggaaaag taaattaaac atacaataaa aataagattt gattcgaaaa
    30601 atggaatgtc tcaaaatgaa atttttagtt catttaaccc tcttttttat atgaaatcaa
    30661 atatattttt atcctttcag caataaaaaa gagacttatc tctattttga gatagtctct
    30721 tctttgaaca taatttaaat acaatttttt aatttttata gttattattt tactaacttg
    30781 ccaatttatg attattttgt tctttaatat gttttgcttt tttaaagaat aaaagaccaa
    30841 gaattattgc tacaataaca cctattccat tagatatatt aactggtagt ctaaatcctt
    30901 cttttgcttg cattatataa ctaaatgtta ctacagtcat aaaaagtgct ggtaatgtag
    30961 ttatataatg gtttttattt gctttgacta aatatgcaga accagtccac aacattatca
    31021 ttgcaagtgt ttgatttgcc caagagaaat atctccaaat tatattaaaa tctataaatg
    31081 taagagcaac accaactgcg aataatggta aagctattaa aaatctattt ttgactgcat
    31141 cttgattata attcattgca tctgctattg tcagcctagc acttctaaat gctgtatctc
    31201 cagaagttat aggacatgcc acaactccaa gtatagctaa agctcctcca ataggcccca
    31261 ttaatccaac agatactgta tttactactg ttgctgctcc accatcatta aatatcacat
    31321 taagttgagg tatgccatgg aaatatgaca tggctgctgc tgcccaaact aaagctatta
    31381 taccttctgc aaccattgac ccataaaata ctggtcttgc ctcactctct ttctcaacac
    31441 atctcgccat aagtggtgat tgagttgcat gaaaacctga tattgctcca catgctattg
    31501 ttataaataa gtatgggaat aaaggtgttc catttggatt catattttgt aaatttatat
    31561 ttggtatgtt ataccccttt attattaatc ctccagctac acctactgcc ataattaata
    31621 atgctgctcc aaataaagga tatattttac caatcaattt atctattggt aaaacagtag
    31681 ccataatata ataaagtatt atcactccaa cccatatttg tgcgtttaca cctgtcaatg
    31741 tctttaataa tcctgctgga cctgttacaa atacaactcc aaccaatact aaaagaataa
    31801 cactaaatat tctcattgct atttttgcac catttcctag ataaaggcct accaactctg
    31861 atgcagatgt acctttgttt ttcattgata gatatcctga agcaaaatcg tgtactccac
    31921 cagcaaagat tgttccaaac acaatccata aaaatgctga tggtccaaat aatgctcctt
    31981 gtatagctcc aaatatcgga cctaaccctg ctatatttag aaactgaatt aaaaagattc
    32041 tcttccattt cattggcaca taatctactc catccctaca agctatagct ggagtttgat
    32101 ttttgtcatt ggttccaaaa accttttcta caaaagtacc atagacaaaa taacctacta
    32161 taagtactac tattgaacct aaaaagctta ccataaattc atccccttag tttttatata
    32221 attgctttat aaatttttat gagtttaaga aaactatttc cagttcaaat agtaatactt
    32281 ttttatgcta atataaatat taattacatt aagtgcatat ttaagtacat gaaatgactt
    32341 tatatatgca ttaacagcct aaattctttt actttgcttc tacttacagt tacttcataa
    32401 tcactatttt ttaattttaa tatgtatgta ttattaaacc atggtataat ttcttttact
    32461 ttggttaagt ttacgatata agacctatgt gttctaaaaa atgttttatc atttataaga
    32521 ttttcgactt ctgatatgcc ttcttttaat ataaactttt ctttctcagt atatataaat
    32581 gtctgccttt cattagcttc acagtaatat atatcatcaa tatctattac aactaattta
    32641 tcacctttcc aaaggctaat tttatgtgtt atttcttcta tctcctgatt tactgcttcc
    32701 ttcttatatt tgtataaatt actatttaca ttaaatagtt caatatcact catctcactt
    32761 ttttctaatt tattcagcat agaaataatt ctctcttcag aatatggttt caatatataa
    32821 tcaaatacat ccaaagaaaa agcatctact gcataacttt catatgctgt tataaaaaca
    32881 attttaggtc ttgatttaaa ctgatttaat gtttttgcaa gtagcattcc atcaagatga
    32941 ggtatattta tatctaaaaa aattacatct attttatttt cctgaataaa gtctaacacc
    33001 tctataccat tggtaaattc acttactacc tcgattccac ttttattttc aataaaatat
    33061 ctcaattcct ttcttgctgg aaattcatct tccactatta tagctctcat acttctactc
    33121 ctttacataa aatactatca aagtcccatt atctattctt cttatattaa gccctcttcc
    33181 atacatcagt ttaagcctta aatgtacatt ataaagccca atcttatttt ctggcatatt
    33241 atcttgatat acattattta taatttcctc acttatacct ataccattat cctctattga
    33301 tattctcaca gtattttcta atgaatacgg taactttttt atggatattt tcactacacc
    33361 agctctacca ctttctaaaa taccatgtat tattgcattt tccactaatg gttgtataat
    33421 caaacttgga atctttatat ttacatcttc tatatcataa gatacagtta gtaattctcc
    33481 aaacctagct ttttctatct ctacaaaaga tttaacttgt tcaatctctt tatttatatc
    33541 aattaagtta tcactatatt caagattata tcttagataa gttgataaat ttattattaa
    33601 ctctctagcc ttatctggac taaatcttat aaatgaagct attgtgttta gggaattaaa
    33661 caaaaaatgt ggattaattt gtctttgaag tgcttttatt tctgctttat ttctcgcttc
    33721 tatatctttt ttatctttct caatcccctc tactatagat ataacaaatc ctattccaat
    33781 ctgcccaact attaaaggta aatatattcc accgattatt tgaattgcta aagaatgtgg
    33841 atatgatatt aagtatataa gtaatatagt aaaactttca gaaatcatgc ctaccaatat
    33901 tccatacatt actctatgtt gttttggtat cctcttatat agaaatcctg ataatacacc
    33961 tgctagtata cttgataaaa gacatggaac agatgttatc cccccaatat ccataaaata
    34021 tctatgaatc cctgaaaaaa ctcctgctgt aatacctacc atcggaccaa ataaaatgcc
    34081 acctgatact atagatatta ttctagtgtt tactattgac cccatataat ttataccact
    34141 ataagttcca aatatggcta aaaaagtaaa aactaatgct atacagacca agtcattaaa
    34201 actatattct tccttttgaa atatctgctt aaatattttt aactttgtta ttagaagaaa
    34261 caatactaca ataaggcttg tcttttctat taatgcgatt aaaattgatg ttttcataat
    34321 ctccctttaa aaaataaatt tttacacact ctaaatttat tatggttgtt ataaattaca
    34381 tatttgaagt aatcctatca caaaactttc cacatttaat cttttaatta aataagaaat
    34441 agttgtactt ctattaacaa ctaatactag ctagcataag cttgtaataa cttgtagtta
    34501 ttattaactt tacaattcta gtatttaatt ttatacttta gaaatctctt ttcttagaaa
    34561 taatactttc gaatatcata taatacaata ttatgtagat tcttactcat acaacatatt
    34621 tctttaaaaa ttttatacta ttctttgttc aaatatctca tttgatttaa ttgtgttaaa
    34681 cacacattat catctctctg ttatatattt attatatagc cgtatatcga taaagtaaat
    34741 aaatcccata tttaaaataa tatgtttgac aataaattat tataatgtat atttaccata
    34801 ataatttgtc aaccttgaaa gttacttcta taattattgt taaataatt
//
LOCUS       DAGQVA010000044        34689 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.044, whole genome shotgun sequence.
ACCESSION   DAGQVA010000044 DAGQVA010000000
VERSION     DAGQVA010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34689
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.044"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="MIV85_002232"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="MIV85_002232"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBY2961564.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="MIV85_002233"
     CDS             complement(2851..3216)
                     /locus_tag="MIV85_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2961565.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="MIV85_002234"
     CDS             3415..4263
                     /locus_tag="MIV85_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961566.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
     gene            complement(4700..5788)
                     /locus_tag="MIV85_002235"
     CDS             complement(4700..5788)
                     /locus_tag="MIV85_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961567.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5913..6641
                     /locus_tag="MIV85_002236"
     CDS             5913..6641
                     /locus_tag="MIV85_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBY2961568.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6843..7334)
                     /locus_tag="MIV85_002237"
     CDS             complement(6843..7334)
                     /locus_tag="MIV85_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961569.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7345..7788)
                     /locus_tag="MIV85_002238"
     CDS             complement(7345..7788)
                     /locus_tag="MIV85_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961570.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7778..8617)
                     /locus_tag="MIV85_002239"
     CDS             complement(7778..8617)
                     /locus_tag="MIV85_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961571.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8836..10221)
                     /locus_tag="MIV85_002240"
     CDS             complement(8836..10221)
                     /locus_tag="MIV85_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2961572.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10394..11137)
                     /locus_tag="MIV85_002241"
     CDS             complement(10394..11137)
                     /locus_tag="MIV85_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBY2961573.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11157..12419)
                     /locus_tag="MIV85_002242"
     CDS             complement(11157..12419)
                     /locus_tag="MIV85_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2961574.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12603..13601)
                     /locus_tag="MIV85_002243"
     CDS             complement(12603..13601)
                     /locus_tag="MIV85_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBY2961575.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13585..15096)
                     /locus_tag="MIV85_002244"
     CDS             complement(13585..15096)
                     /locus_tag="MIV85_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBY2961576.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15150..16112)
                     /locus_tag="MIV85_002245"
     CDS             complement(15150..16112)
                     /locus_tag="MIV85_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBY2961577.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="MIV85_002246"
     CDS             complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="MIV85_002246"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBY2961578.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17092..18105)
                     /locus_tag="MIV85_002247"
     CDS             complement(17092..18105)
                     /locus_tag="MIV85_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBY2961579.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18333..19310)
                     /gene="bioB"
                     /locus_tag="MIV85_002248"
     CDS             complement(18333..19310)
                     /gene="bioB"
                     /locus_tag="MIV85_002248"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBY2961580.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(19516..19779)
                     /locus_tag="MIV85_002249"
     CDS             complement(19516..19779)
                     /locus_tag="MIV85_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961581.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19849..20922)
                     /locus_tag="MIV85_002250"
     CDS             complement(19849..20922)
                     /locus_tag="MIV85_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBY2961582.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21181..21939)
                     /locus_tag="MIV85_002251"
     CDS             complement(21181..21939)
                     /locus_tag="MIV85_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961583.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISIVCLLAAVILFNKKPV"
     gene            complement(21936..22853)
                     /locus_tag="MIV85_002252"
     CDS             complement(21936..22853)
                     /locus_tag="MIV85_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961584.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22853..23053)
                     /locus_tag="MIV85_002253"
     CDS             complement(22853..23053)
                     /locus_tag="MIV85_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBY2961585.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23058..24152)
                     /locus_tag="MIV85_002254"
     CDS             complement(23058..24152)
                     /locus_tag="MIV85_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961586.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24662..24802)
                     /locus_tag="MIV85_002255"
     CDS             complement(24662..24802)
                     /locus_tag="MIV85_002255"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBY2961587.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDIYPDSGWGFMTWDEN
                     GE"
     gene            complement(25112..26419)
                     /locus_tag="MIV85_002256"
     CDS             complement(25112..26419)
                     /locus_tag="MIV85_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2961588.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIVHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26484..26963)
                     /locus_tag="MIV85_002257"
     CDS             complement(26484..26963)
                     /locus_tag="MIV85_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBY2961589.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27010..27873)
                     /locus_tag="MIV85_002258"
     CDS             complement(27010..27873)
                     /locus_tag="MIV85_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBY2961590.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27873..28628)
                     /locus_tag="MIV85_002259"
     CDS             complement(27873..28628)
                     /locus_tag="MIV85_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2961591.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28655..29143)
                     /locus_tag="MIV85_002260"
     CDS             complement(28655..29143)
                     /locus_tag="MIV85_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2961592.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29161..29562)
                     /locus_tag="MIV85_002261"
     CDS             complement(29161..29562)
                     /locus_tag="MIV85_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBY2961593.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29565..30062)
                     /locus_tag="MIV85_002262"
     CDS             complement(29565..30062)
                     /locus_tag="MIV85_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2961594.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30086..30490)
                     /locus_tag="MIV85_002263"
     CDS             complement(30086..30490)
                     /locus_tag="MIV85_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2961595.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30720..33287)
                     /locus_tag="MIV85_002264"
     CDS             complement(30720..33287)
                     /locus_tag="MIV85_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2961596.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33453..34196
                     /locus_tag="MIV85_002265"
     CDS             33453..34196
                     /locus_tag="MIV85_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBY2961597.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT        11236 a         6354 c         3558 g        13541 t
ORIGIN      
        1 cttaaaaata attcgtcaat actttttaaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaacgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaaaaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgttaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggctctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcatgcc taacaatgtg cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggca tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctgtac aaggtatacc acaagctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtgttgg tgattcagaa
     4501 tagtatggta ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attgaccaca ataataaatg tattcctcat
     4621 aatattcccc caatattata gaaataaatt taagcgagat taaattcagt taatctcgct
     4681 taaataatgt ctaaatttat tattccaaaa aatcatcaaa atctaatgaa cctgattctg
     4741 caaaatcata taatgcattt tgctcaaaga aaaatttctc ttcaaattta atatagtcgc
     4801 tataattaga ttgacttatt tcattgatat aattgcaatc attttcgtta taagtaccaa
     4861 taaaaaactt atttcccatt aagtaatata tagctttcat atcattattt attatatata
     4921 cattttcttt tacatggtca ttattaaaat taaatctagt aaagaatata ccttcattca
     4981 tattactttt taacagaaat ggattttctc tataaaatac tcctgcaaat tcttcaggtg
     5041 aatttacact gtaaacactt acaaattcac ttttagaaat ctcatcaaat acctcaaaat
     5101 catacatagg ttctttatct gtcactaata gagaattaat tctaaaacca gtttcataac
     5161 acttacttat gcaaaaagca attttacata tataatatcc atcattatct tcatataaag
     5221 cttcacttat atatctgcct tgacctttat cacttaccac gtttttaagt aatgttccat
     5281 ttatattagt aatgtgcata tttgcaatct cgtcacttcc agaaaagtac tttaaacttt
     5341 ctctatccca tgctataaat ctcatggtca tatagtttat aaattcaact tcctcgtcaa
     5401 ctcttttaca tattttattg tataattttt ctatagttaa atctgtttta tagtttttta
     5461 taatatcaat atactcacat ttatctcctg gcaatagctt atcataataa agattcttat
     5521 taccaaaata agatactaaa aataaagatt catccttcgt taattcaact ctatctgaac
     5581 caaatcctcc catcaatctt tcttcttcca tataagcttc ttcttgtgtt gggttattta
     5641 aactcacata atccgctaat cctaatccct ctgcatctaa taaaaaatat tgacaaaagt
     5701 gattgttttc atcatctatc caatttatta taagacctaa actgcccata agtctagaat
     5761 ttgtagcctt tgcaaaatta aaattcatat agtcacatcc tttaaactct aaaatacttg
     5821 ttttttaata tataaattat tatacatata ttttaacaac ttagatacaa tttataatat
     5881 aatataagga aatgattaat tgaggtggtc ttatgaaaaa tatagcagct ttttttgata
     5941 tagatggtac tctttataga gactctctta tggttgaaca ttttaaaaaa ttaattaaat
     6001 acgatataat tgaccaaaaa aattggtata aacatgctag agacactttt atggattggg
     6061 ataaaagaca aggtaattat gatgattatc tattagaaat atgtgacctt tatgttgatt
     6121 cactaaaagg attagataaa acctgtatca actttacaag tgaccaagta attaaattaa
     6181 aagcagatag agtttataaa tacacacgtt caaggattga gtggcatcta aatcaaggac
     6241 acatagttat atttatatct ggtagccctg gatttcttgt tgaaaaaatg gcaaaaaaat
     6301 ataatgtaac cgattttcta ggaagtgatt atgtctttga aaacaatata tttacaggca
     6361 cagttattcc aatgtgggat tctataagta agaataatgc tataaacgat tttgttgtaa
     6421 agtatgattt agatttatca aactcgtatg cctatggaga tactaatggt gatataaata
     6481 tgctaaaaag agttggaaat ccaatagcaa taaatccaac aaaggaactt ttatctcaaa
     6541 tatcacttga tgaggaaatt tctaaaaatg ttgagataat agtagaaaga aaagatatta
     6601 tttattctct atctacagat gtaaatatag tggatattta atttatacta tctattttaa
     6661 aaacttatat tatatctaat atttatatct aacatataaa agctttgact aaaaatcaaa
     6721 gcttttatat gttgcactaa gaatatatta aatttagctt tatgctttaa tgtatattca
     6781 tatatatcat ttacacttat ctaaactaca atttcattaa aattaaatat aaaaatcaac
     6841 tattattttt taaatagcat ctttcttaat ctattattgt aataacctat aaaagaactg
     6901 taaacatagt catatactat aaaggctatc tcaaatgaac ctataataaa tatgtttatt
     6961 ggaatataaa ctattgttct taataaaaaa tacaatataa gtatcattat atttgcaaat
     7021 actaatttca taaaatactc aatatatata gacctatctt tttctataag atattttaca
     7081 ataccatata ttccaaaggt aagtgaatat acaatccatt gagacttact tgccatcact
     7141 ataaatccta aaactataga acctatataa aaagcaattc cactcttaaa gccccattcc
     7201 attattacaa ttgatactaa aagtgatgct aaccccataa taaacaatgt atttacagga
     7261 ataatgtttg taagagtcaa caatatcaca tttaatgcta ataaaactcc tccataagca
     7321 acttttatac tcatatttat catcctaaca acaagttatt aaatctccac caaaacattc
     7381 acaacatgaa tctaaacacc aaagtttagc acaattttca caacaatcgt cacctagaca
     7441 acaacagcaa tcatcacagc aacagcaaca acatccatct aaatcattac gtcttcttct
     7501 attataattg tcagccctat tgctataatc atttctatat tgtgtataac ttctaagtgc
     7561 atcactatat tcactatttt caggctccat aaattttgct ctttttaaga agtcttcacc
     7621 ttcttcataa tatcctatgt tcattgcaga aaaaccagtt aaataatacc actctgcaca
     7681 tttgtcagtc aaagttttta aaaaatcata tgctttttta aattcactat tttctatgaa
     7741 tgatcttgct ctcataaaat tttcattatt ataagtatta ctgtacattc tttccacctc
     7801 tactttctaa tatattaata tatcttaaat aaacaccaga ataaattata ttttctatta
     7861 ttccaacatt tttatttaga tttagattat caattcccct agctaaaaat cctaatgatg
     7921 ttactattat tttttttact ttttctttta actcatcatt tttatcaata tactctataa
     7981 atggattata tcttcctttc ttaaaatctt catctaaatc ttcataggca tctagtagat
     8041 atatatactt acctatatta aaacctatca ttcttaagtt tctctcattt tcatcttttt
     8101 tatagacaaa tacttcaccc attatatttc caaatatact agatacttca tctatattta
     8161 tatttttatc tttttctaac ttatttaatt catttagttg ttgttttata tactctgctt
     8221 tttcaggata cttttcatat gctaatttta atttgttttt atatatataa tatgccaatt
     8281 tatcttttat gcgtttatca tccattaaat tatcttccaa tttataatac gttaaaagaa
     8341 tattcatact tgctgcatat tctgtaatat catttgtaat tacctttttc tttttaaatg
     8401 gatttactat acacacttcc tctgtactta tagactctgg gttatatact gctgttaata
     8461 aaacaattaa aaatgttata tcatagttca aagaaaacct agagatttct ccatgatttc
     8521 tttttaagta tttacatagt ccacaatagt aagctttgta ataatcatat tctctaaatg
     8581 ttaaatccat tttgtttatt ttaacatatc caaacataaa tactcctttt tgtactattt
     8641 tttatttaga ttatatatag tataacactt tttatcaaga ttatataatt tacagtattc
     8701 taagaaactt aaaaaattcc ttctaatcat tgtatcttaa atttaaaata attagaaggt
     8761 tgggttaaaa ataatattaa attatatact tatattaact catacaagtt agttatgctt
     8821 atatcaattt aagttttaaa taattggtat atatttaaaa ctacctacag tatccttcaa
     8881 ttcttttttt gctttgttta taaccaattc atcaagcatt acatcattta ttgaacatga
     8941 tatagattta gatgccaata acattgcctt aaatcccata tcagaacctg cactggcaca
     9001 agattgccat gtatgggcag aaataccaat aggccaaact gaacaagaac actgtgctgt
     9061 aggaattatg tagctaacat ctccaatatc taatgataat gatatacagt tattatgagt
     9121 aaatgtatca tccgtaactt catcatgcag attcatctta gtaatatcct tatttccact
     9181 taatacacta gaaacactac ttcttttatc tatagacact gtctcagcta atttatctgc
     9241 aaaatagtag tcatcttcat tatagttttg cacacctact aatttcatat tttgtgatag
     9301 aatatctgtt aatattgtat ttggaatata gtcatatact ccacttataa tgtcatattc
     9361 cataatagta ccagtcatta atgctgctcc ttttgctata tcaacaatcc taccaaatac
     9421 atctcttaca tgctccattt taactcctct tatgtaatac cacacttctg caaaatcagg
     9481 aactatattt ggcatttttc caccattagt agttacatag tgtactctac aattatcaaa
     9541 tatatgttct ctcaaataat tacaacctat attcataagt tctactgcat caagtgcact
     9601 tcttccgtta taaggagctt gtgctgcatg ggcactaatc ccattatatc taaatttcac
     9661 agagtaatta gcaagtgttg gtattcttat tggagtattt atatcaaatg gatgccaact
     9721 aaaagcacaa tcaattccat caaaaaaacc tttttttatc atcaatactt ttccagataa
     9781 atcttcttct gctggacatc catagtattt tatagtccct ttcagctttt ttagtttgat
     9841 taattccttt actgcaatta cagctcctat tgaacctgta ccaagtaagt tatgtccaca
     9901 tccatgacct gcaccaccat ctacaatagg ttctttagta gtggatactt tttgagacaa
     9961 accatctaaa gcatcatatt ctcccaaaac tgctataact ggtctacctt ctccataact
    10021 agccacaaat gctgtatcca taccttctaa tccctctata ctaaaaccat gtttttttaa
    10081 acattctttt tgtaaatttg aagcatagta ttctttatac tgaagttctg gatttttcca
    10141 tatcttatct gatatatctc ttaattctcc ctgtatctca tctatatatt ccatcaaaaa
    10201 ctttttattt aaattatcca tattaattat ataaacctcc ctgtttctaa taacttatcg
    10261 attatcagcc aaaatgacta attttaactg atttaaaaat attttctacc atacaaccat
    10321 tttatacaat aaaacctctt gacttgtaag tttcatttta tcaagtaaga ggttttcaag
    10381 ttttataaaa tttttagcat gttaaccaat caagcatatt aacccataat ttattatagt
    10441 atttccaatc agtaaattct tttggacccc agtgaggtgc acagtcagaa ctaaagatag
    10501 cagattttcc ttttccaaac tcgccaacag ctacaaatgg gtctcctcca atagttgcta
    10561 aaacaggaca attatctcta gctactgttt tgttatatcc taaaaacttt ggccattctg
    10621 ttggtatacc ttttaatact ggatgttcag agtcaataac ttctggaatt attcctgctg
    10681 gtttttcaac tctatcatct ttatctatca ttgttattgg taatacatct ttgatagcag
    10741 tttctccaaa tctagctttt gcatctattc ctgtaaatga catatatcca cctaccatga
    10801 ttaacgcccc accattattt acatactctt tgattagttc aagtctatct ggattactat
    10861 tgcaatctat aaaagtacta ttagataata agaacgtatt agaacctata tcagataata
    10921 ttatacagtc atactcattt aactcttcta atttatacgg aaaactatct gctgctacat
    10981 gtgcaggcat atgaactgtc tcatatcctc cagattctat tgcttctttc aaccacttta
    11041 cagcttcttc ataatgagtt gtaacaaacg tatcaaaccc ttttatatga gttatatttt
    11101 ttacccaaga ttcccctact attaatactt ttttcattta tatattcctc ctacttttat
    11161 aagtttaata ttagacttgc atacataagt atactatcta aatactcctt aatttcaaca
    11221 tattcatcaa ttgaatgaca ttgttctatt gaacctggcc ctaatataag tgttggtatt
    11281 tcagctaaat ttttcattac tctcgcatca ttgccagctg ttgaaccttt tatctctaat
    11341 ttttttccta gagtttcttc tagtatttta tgtgcattca ctacaaaatc agaatccttg
    11401 tccatctcaa aacctaaccc tgattgatat atgtttatat ttggtttatt atctttaagc
    11461 cataaatctc cattagccct tgtcattatg acatttgtta catcatttac aacttgttca
    11521 taactcatta tatttggcaa gaagtgtaca cataaattaa atacacactt atctggcaca
    11581 gtagaacctg ctgttccacc atttattaca cctaaattta ttgtaggtga aggtaatagt
    11641 ggatgtttat atatcataag ccagttatgt tccaactctt ttatatcttg aagcaacaac
    11701 atagccttct caattgcatt tacaccctcc cacttactac cacagtgaag agacacacct
    11761 ttaacctcaa cttcaaagaa tacaaatccc atatgtgcaa ctattaagtt ttgttctgat
    11821 ggttcacaaa ttatgcaaca atctccatca ataccattca taactgcatt tatggtacca
    11881 tttccgccac cttcttcatc tactactgac attattttta cattaccagg tacatttaga
    11941 ccactatctt ttataagctt tacagctaat attgatgcta taagtccaga tttcatatca
    12001 gcagttccaa gaccataaag ttttccatta tcttctgtag cacgatatgg attatatttc
    12061 cacttactta tatcacccgg tggcatagtg tctacatgac cattaaatac aattgtctta
    12121 ccaggtaaat catcactata cttacaaatt aaattatatc tatcttgata attgtgacct
    12181 agatttcctt ctttatatat attttttgct tttttaatta attcttcgct catttcttgt
    12241 ctatccacac taaaacctat gtaatttgca agtttttcaa tatattcctg tccttctttt
    12301 tcaaatccac ctagtattcc atgaccaaca tcttcagtct ttatacttac aagttctttt
    12361 aaataatcta tgtattcttg ttttttacta tttaatgtat ctaagagaat ttttttcata
    12421 tttcctccta agatttattt ttacatttaa aatttcaagt ctaatctcat ctatttaagc
    12481 catagtaaac tttttcactt agcatattct cattcaatgt ataaagatgt atgcaaatta
    12541 aagtataaaa atatatacaa aaacttaata atttttatag tttataagct aaaatttaat
    12601 tactatttag atttagctga tttttttaat tttatattat ttatccatat agcaaataac
    12661 attaccaaac cttttataat catttgatta tatgaagata cacttaataa gtttaatcca
    12721 tttcctaata ttcctattat tccgacacct atacatgtac ctactataga accagaacca
    12781 cccatcatat tagtaccacc aagcacaacg gctgctatag catccaattc tgctccatct
    12841 ccaacagttg gtgaacctga tgccaaacgt gatgatagta ttatcccagc taatgctgtt
    12901 agtagtccag ctagtgcgta tacttttact ataactttat ttacttttac tccacataat
    12961 ctagcggcct cttcatttcc acctactgca tgtacatgac gtccaaaatt agttcttttt
    13021 aatagaaaat gtcctgctat tacaactata atcataatta taactggtat tggtattggt
    13081 ccaatatatc ctctaccgag catcttaaat gcatctgtat ttactgatat aggtcttcct
    13141 cctgtaaata caaagcttgc cccacttatt atcgttaaca tggctaaagt tacaatgaat
    13201 ggaggtagtt tttgtgttga aataattgca ccttttatga ctcctaatat tgtccctatt
    13261 gctaatgcaa gtatcatacc tacccatata ggtgcattat aattcactac tgttgtagcc
    13321 caaaatgtac ctactaaagc aattactgct cctacactta aatctattcc tcctgtaatt
    13381 attacaaatg tcatacctac tgcaagtatt gcatttattg atatttgtct tccaacatta
    13441 attaaattat ctaaagttaa aaagttagat gaagctacac tcattattat aaaaattatt
    13501 acaagtccta cagctgcact cccttggtct ctaaatacac ttgttaattt tgtcaataat
    13561 ggagaagatt tttcttcttt atgcttagtt attgaactca ttaattttac ctccgaaagc
    13621 caattttaat acattatttt caaccatttc ttcaccttct aaaaatccac ttatatgacc
    13681 ttctctcata accattattc tgtcactcat tgatattaat tctggtattt cagaagatat
    13741 cattattata cttacaccac tctccactaa atctcccatt agattgtata tctctgcctt
    13801 agcatttaca tctatacctc tggttggttc atccataatc aatatatctg gttgtaataa
    13861 aagccatctt gctattatag ctttttgttg gtttccacca cttaaacttt gtataacttg
    13921 attcatatgt ggtgttttta tctttaaagc ttctatgtat ttttctaaaa tctctttttc
    13981 cttttttcta tctataattg atttaaactt agatatcttt tttaacccag ccatagttgt
    14041 attttctttg acactcattt gtaaaaacaa tccagtacct tttctatctt ctgttattaa
    14101 tcctagtcca ttttctattg catctgatgg agttttaaac tttacttctt cattgtttaa
    14161 atatattttt ccagaatcat atgttctaag tccaaatata gcttctacta tttcacttct
    14221 cttacttcca actagtccac ctattcccaa tatttcacct tttcttatat taaagctaat
    14281 atcattaaaa acattgttct tagttagatt ttccactcgc ataatttctt cttttatttc
    14341 tacttttctt tttgggaaaa attggtctag ctttctatct atcattaaat taactaattc
    14401 ttcctcagac gatacatctt tggtatttaa agtcgaaatc gttttcccat ctcgcattat
    14461 agttattctg tcacaaatct caaagagttc ttccatccta tgggatatat atattatact
    14521 aactccactc tcttttaaat catttataag tctaaaaagt atttcagtct cttttttact
    14581 tattgaagaa gtaggttcat ccattattaa tactttagtt tctgatgata aaactcttgc
    14641 tatttctacc atttgttttt gagctatact aagctctttg actaaactat ttggatttat
    14701 atctattccc atattatcga aaatcttttt agcctcttca ttcatttttt tgtcattggt
    14761 taagactttg ccatttattt cttttcccat aaaaatattt tgtgctactg ttaattcgtc
    14821 aaaaactgtt agttcttgat atatggcatt tatacctatc tttttagaga tatctgggga
    14881 tatattctct atttctttgc cttcaaaaat aaattttcca gaagttttcg aatgtgcacc
    14941 agttaaaatc tttatcattg ttgatttacc agcaccattt tcacccagta gtgcatgaac
    15001 ttcgccatga aataactcaa aattaacatt atctaatgct ctgacaccag gaaattcttt
    15061 agcaatatta cttaacttca gaattatatt actcataatg acactccttt ttaaatagga
    15121 tttctttcaa ataatctcat tttattttac taattcttaa agtcttttat attttcctta
    15181 tcataaagta aagctggtac tggtatattc ttttctacct tttccccttt tatagctttt
    15241 actactgctt ctacagctaa acgtcccatc tctttaggtt gttgttgaat catagcaaga
    15301 atagttccat ctgttattcc acttgatgct tcttcagtta agtcaaatcc tacaatctta
    15361 acatccttat tttttgcaga ttcaagtgca gctttagctc ctagtacact attttcagct
    15421 gttgcatata ttatatctac atctggatta gattgaatta agttttctac tgtattaaga
    15481 gattcttctc tgtcatatcc tggttgtgaa tttaatatct taacatttgc tgaacctttt
    15541 aatgcatctt taaatccatc tattctctgc atttgtattt gagattttaa atctgtcact
    15601 attgctattt ctgactttcc acctaacttt tcatctatgt attttttagt gtattcccct
    15661 aattttttac cagcatcata actaactgtt cctacataac ttgtaatatt ttcagtattt
    15721 aatacagcat ctactgtaac tactggcatt ttttcaaatg ctccttctac tgctggtact
    15781 atagccgaat tatcagttcc aagtactatc attccatcta cattttgttg tataaaatct
    15841 tctattgctg atgtttgctt agctacatct tggtctgggt catttactat aactttcaca
    15901 cctaattctt tagctttttc ttttattccc tcatcaatat ctataaaaaa ttgatgttga
    15961 agagttattg tagatactcc aatagttaaa tctttcttgt ctgaaccacc tttattatct
    16021 gatttacttg gtccttccat tgaacaccct gttaacattc ctattgctag tattccagca
    16081 attcctaaag ataaaatttt tctcactctc ataattaacc tccattttta atagttttaa
    16141 atttgaacaa attagatttt tatttattat ttaaatattt ttcaacatct tctttataag
    16201 gcataccaga ttgtgcacct agtttagtta cagacagacc tgatactact actgcatatt
    16261 ctactgctgt atataaattt ttcccttctg ttatagccac tgccaatgct ccattaaatg
    16321 tatctcctgc tcctgtggta tcttgaacat caacacttat acaagataca tgcttgattt
    16381 cctcaccatc ataaaatcta gctccatttt ttccttctgt tattacaagt ttatttggat
    16441 atttttttaa tacttcttct atcccttcat ttgtgtcaaa aactatctta tattcatgtt
    16501 catttggtgt taagtaagtt actttttcta ttatatcttc atttagtttt actgctggtg
    16561 ctggatttaa taaaacccta atcctatttt caaaacagaa attcactaca taatttattg
    16621 tttttaatgg aatctctaat tgtagcaata ctatatctgc attctttatc tcttcttcat
    16681 tctttttaat taattctata tctactagct cattagtccc tggtacaaca acaatactat
    16741 tatcattttc acataatgtt ataacagcaa caccagaact tttgtgatta tttctggata
    16801 ctaagctata atcaacttta ttcgttctaa aatttcttat taactcctct cctaagccat
    16861 cttcccctat gcatgatatc atttttacat ttgctcctag tttagaagct gagatagctt
    16921 gattagcccc ttttcctcca ggtgatgtaa aaaaactatt acctaatact gtttctcctt
    16981 tttctggtct tttatctaca gaacatacca tgtccatgtt tacacttcct atgacaacta
    17041 tgtttcccat tacattactc ctttacatat ctatttatgt ctctcgtgct gttattcact
    17101 ttcttttgtt gaatctctta tgaccaattc tggtttgaaa atcaattcat caaacgattc
    17161 ttttttatct cctcttaaac aatttatcaa tatttcactg gctttatatc ctatatcata
    17221 agacggctgt tttactgtgg taagagaagg gcttattaga cttgatgttt gaatatcatc
    17281 aaatcccacg acacttatat catttggtat acttaatcct ctttctttaa gacctcttat
    17341 gacacctatt gcaatcaaat catttgcaca aaatattgca tcaaaatcta tcttttctaa
    17401 attttttata aattcttgtc cccattcaat cttatatttt ccttcaaata cataagcagg
    17461 attgtagctt aaattgcact cgattagagc ctttttatat ccttctaatc tatctactgc
    17521 tatttcattt tgaagtggac cacttaggta tattattttc ttatttccaa tatctaataa
    17581 atgttttgta gctatatagg ccccttcaaa gttatttatt ttaacaattc cttttaaggt
    17641 ttctttgttc atacttatct tcttatcaat caagacagtt ggtattttta tatctttata
    17701 atttgcttct ttccagtttg tatttgaaga tgctgcaaat ataattccat ctatcatcct
    17761 ctctgatagt gttcttattc cttcatattc ttttttagca tcttcatctg tattacataa
    17821 aattatattg tagccttctt cattagcttt gtcttctaca cctcttgata catctgtaaa
    17881 gaatggattt cgtatatctg gtataagaag ccctatagta ttagtttttt tagttactaa
    17941 actttgtgct aatttatttg gtacataatt tttttccttc attattttca aaattttttc
    18001 tcttgttgcc tgacttatat tttcatcttt attattaatg acttttgaca cagttgtttt
    18061 agaaacacca gccaattcgc caatttcttt tatagttata ctcaagaagt tcacccccaa
    18121 aatttaggaa accgttttac ttaaccggtt acctagatac tatcacatct tttttccatt
    18181 tgcaaccatt ttatataaat tttgatattt ttcccttttt tcaaaatatt gcaacttata
    18241 attcaatttt aatatttaaa ttaatctgaa aaaaaaatta atatactttt ataattatct
    18301 aaaagtatat taattaattt aagcagtatt tattaaagtt caaatccttg ctctataatc
    18361 atttttttat cattttcaat cccacttcca acagttgtca aataatcacc aacaattgca
    18421 gaatttactc ccccattaaa tccaactttg tcatatccct ttaatgatag ccttccacca
    18481 gcatacctta tgtacacatt aggaattata aacctaaata ctgctgttgt ttttagtatt
    18541 tccattggtt ctaatacatc ataattttcc attggtgtat tcttaatagg atttaaaatg
    18601 tttattggaa atgattttac atttaattct cgtatttcaa aagccatttt tagtctctgt
    18661 tcttcactct cattcattcc aattataccg cctacacata catctagccc agctttttta
    18721 gcatctttta tagtttttat cctatcttta tatgtgtgtg ttgtacatat attatgaaaa
    18781 ttatctctac acgtctcaac attgtggtga tatgtagtca cacctgctga cttcaacatt
    18841 ttagcttgct cataatctat aatacctaaa gatgcacata attttaaatt agtattttcc
    18901 ctcaatcctt catagatatt taaaatatta ttaaactcct ttcctgacat acctttacca
    18961 cttgtaacca atgagaatct atgcactcct ttactctcca tctctttagc tctatttaag
    19021 atttcattgt aatctaataa tgaatattct tctacaccag ttttataata agaagactga
    19081 gcacaaaatt tacagtcttc actacatttg ccagatttag cattcattat cgtacataaa
    19141 tctgcttttc ttcccataaa atattctctt atttcatttg cagattttaa tagaatatca
    19201 aaatcgtttt tattatttgt atcaaggctt attaaattaa gagcttcttc ataacttatt
    19261 tctttttctc tcaatacttt attttttaat tttattatgt atttttccat atatcctcct
    19321 atttgtcaac ttaatatttt tatgtagttt acttattata tatagtattg catatataac
    19381 atttattggt caactttatt ttagacacaa gtttactata cacaaaaaaa tactgcttca
    19441 aaacaatatt agtatataga ttatacatat tattattaaa gcagtatttt ttattagaat
    19501 ataattctta ctggtttata aaactatcct tgtcttaact ccatccaagc tttccattgt
    19561 aataacttct aagccttcat attctctaaa tagccatttt aaatccttca tggcttgatt
    19621 aacctgactt tttgttagat tatttataaa atattctttt ctagtttcct catactcttt
    19681 gctagtcaaa aagtttctta gaaaattaaa cgcaaataca cttggaatat tgtttacatt
    19741 agccttcttg ctgttttcct tctcatagta aattttcata aatgcatact cctttgatac
    19801 ttttagattt ctcttacaat aattatatgc atttaagtgc tactattctt ataattttat
    19861 taattcatat tctttacttc ccatacccat ttcacatgca tagtctatta ttctagttcc
    19921 atttacatga ggatgttcat gtttgaaaac atcatgaccc atttccttac aaatcaaatc
    19981 atagcatgct tgttcaatag ctacagggtc tgttgatgct aatattccta tatcatgggc
    20041 aattggtcta cctgaccaag gtacacaatc acaaagtgga gttacattca taacaaaagt
    20101 tatataccct accttgtctt ttttatttga tactgctcca taagcgtatt ctgccatctt
    20161 ttcgacaaac acatctgagt cactttccca ttgtatagtt actgctctag ttggacagac
    20221 agttggacat tctccacatc cataacatac atcagaatct ataactgctt ttttatccac
    20281 tatacttata gcttttgtag gacaagaatt aacacacttt ccacaaccta cacacttctt
    20341 ttcctttact actggagtaa catcagaatg ttgcatttgt tttcctgctg cacttgcaca
    20401 tcccatagct aagtttttta atgctcctcc aaaacctgct gcttcatgac ctttaaaatg
    20461 actcattact atcattgcag aagaattata aatttctcca cctattttta cactttcaaa
    20521 atgttttttg tctattttta cattctcata atttctacta tataatccat ctgcaattat
    20581 tactggtgca tttacaactg cataagcaaa tccattttct atagcagttg taagatggtc
    20641 tacagaattt gttctactcc ctgtatacag tgtatttgta tctgttaaaa atggctttcc
    20701 ttcgcagtct ttaaccttat caaccacttg tctaactgcc acaggactca tatatgtagt
    20761 atttcccttt tctccaaagt gaagtttaat tgcgacttgg tcattttttt ctattaaatc
    20821 tttgaatcct gcttcatcaa ataatcttct tacattgttt ggtacgtttt tattttgcga
    20881 atttgagtat aaatcacaaa aatatacttt tgacttttcc atatctacac ccctttaaaa
    20941 tatttactta tactaatttt atcactttta aagtaatttt tagtatattt taacataatt
    21001 aaatattctt atatttattt gatacaaata atattatttg tattattttc tacacttaat
    21061 tctatatatt aaactacacc taaaaatcaa aaagacttga aacttaagtc caagtctttt
    21121 tgatttttag gtgtagtttt taacaacata agattacttt accttgtgat aaaggtatta
    21181 ttaaactggt tttttattaa ataaaataac agctgctagt aaacatacta tagaaataag
    21241 aactgttata ataattggaa taataaattc tggcattgcc actttccctg aaatcaagtc
    21301 tatatttttt gacatcaaga aattaggagt ataaggtgca atctgtttag gaatagaaat
    21361 taaactcaat aagagagttg ctaccaatac aagtaaaaca ctggcaaatg ctggtctaaa
    21421 tagtacacac ccaagaatta atacactaat atacataatt cctataagcc ataaattaaa
    21481 tgctgaaaat ataatatgat taagatttgc agttggccaa aaatacattg tatagccata
    21541 agcaaataaa aaactcaacc aaaaaccaat tgtcataata atcaccgtaa cagagaattt
    21601 agacaatact atagatgaac gtgataaacc tttagtcagc ataataacaa gtgtcccttt
    21661 agaatattca tttgataaaa tattacaaaa aataattaga gttaaactca taccaagacc
    21721 agagatattg ctaaaaaatt gtgtccaaga atctaaagca gttggtgcag cagtaacttt
    21781 taaagtcggt gcaaaatgag caatcaagtc tggcataaat tttgcagaaa taggactact
    21841 tataccaaat attagaaata aaataattaa actaaataat ttataatttc ttaaattctc
    21901 tttaaattct ttttttgtaa atgctatgta ttctctcact ttactacctc caaaaataaa
    21961 ttttcaagtg ataattctat tagttccatc tttactggac aaagattcat ttctgcgagc
    22021 gtagatataa ctgttttttg tattgctttt atatctttac catgcaaaac aatttccata
    22081 ttagtttctt ctgaatcttt tagtaaggat ttaataccat cactagactt aaacttttga
    22141 atttcatcat tacttgcaaa ctccagtaaa agtctatcct ttccgtgcat actttttatt
    22201 tctgaaagtg taccactaag ggcaatgctt cctttgttta atatagcaac atggtcacag
    22261 attctttcaa catctgatag tatatgtgtt gaaaatatta cagttgttga gtctttgatt
    22321 ttaagcataa tatctaatat ttcttttcga ccaacagggt caagtgcact tgttggttca
    22381 tcacaaataa gtaatttggg gcgtgaaagc aaagcttgag ctataccaag tcgttgcttc
    22441 attccacgag aaaacccacc tattcgtctc ttttcatttc taagacccac aagtgataac
    22501 aactcttcac tccttatctg tatttctttt tttgaaagtc ccgtaatttc accacaaaga
    22561 gaaagatatt caagtggtct catataattg taaaactctg gaacatcagg cagataacct
    22621 acatgacgat tagaacttgt tttcccatag gtcactttct caccacaaac atctatagtt
    22681 ccactatctg gtttaagtaa cccaagtacc attttcattg ttgtagtctt acctgcacca
    22741 ttcttaccta caaacccaaa gactgaccct tctggtacag taaaatttaa attatctatt
    22801 atctttcgat taccaaaacc ttttgataat ccatttattg agacaatatt catcattctt
    22861 cacctcttcc tattgtaaaa tacaaaattg gtcctattaa actaataaac agtactacaa
    22921 taatccatat tgccttattt ccaattttat aatttggatg tctcaacaca tgaacaagtg
    22981 cagtaattat aagtattaaa tctaaaataa taacaggaac caaaagtggt aagtattcca
    23041 tcaaattttc cataatctta ttcctccaat aaagataatt tttctataag aaatttgtat
    23101 tctttgtttt cacttaatac agaaaacatt ggattatttt taatagcagc aacaatacct
    23161 gcttttacga ttgtatcatc acgtgtaata cctgttccaa tttcagaaat ccatctgtca
    23221 agtttattaa aaaagtcatc cccatgtatt ataattgggt atatatcacg tgttgctaaa
    23281 tctacatatt ttcgtaatga tttaatagct ccttcattat caccatgtat taaattaatt
    23341 tgtgcctgtg ttaaatatga agaaagcata atagcaggag ataatgtatc aagctcaaat
    23401 atatctgaaa ttgctagaat acgtctttct atttccttca tttgtaattt atctgcattt
    23461 tgcaaaatac ccactagatt ttggactaat gatataaggt tctgatatgc accaagttga
    23521 aatgtttctc ttgcttcatc catttgacca ttcatcattt gcccttgtgc aagaagtata
    23581 gattcattta tcatgggaaa attgctgttt tgcaataaat caatcacttg tatgggttga
    23641 tttaacaata tataacaagt tgcctccata ctttttgctt gacggcaaat atctatgtca
    23701 ttacaagttt cctgtatacg aataaatatt tctaatgctt cactaattaa tagttcacgc
    23761 tttttttcat ctacaatatc atagtgatta actattaaaa gacccatccg aaaaatcaaa
    23821 ggaaaacatg aataatattt ttttatgatt tctcttattt catccatgac ttcatcaaat
    23881 ggtttaaccg taaagtcttt gcacagttta ttatacagtt tattaatatc ttccttcatc
    23941 atttgaggtt cataacatat taactcatca acggtaatgt tgaaatatgt cgcgagttgc
    24001 ggtaaaaagg ttatgtcagg atagctttgt ccagtttccc atttagatac agaagcttta
    24061 gaaacgccta tataatttgc aagttcatct tgtgtaattc ctttttcttt acgctttaaa
    24121 atcagcgttt ttgcgatgtt taattcattc atgtcaatcc ctccttatgt ataattatat
    24181 ccttaaacat gtaaagctaa caagcgattt gaagttgact tttgacgaaa aaatcaacca
    24241 cagagaaaca aataaacaag tatataaaat atatatttaa atttatcttt aatctccttt
    24301 gtaaaatatg taaactttgt aaataaaatc catattatat aaaactaata gttaatctat
    24361 ctaaatacag tttttattta tcacgttttt aaatattttg tgtaaaacct cttttaatat
    24421 aaacacctta ttttcatttc tcatttcata ttctttttaa aatactgaat ataactcttc
    24481 gattttccat ttaatccttt tataaagtta ttattcgtat ttattcctct aattataaca
    24541 ggcaactatc atgtattggt atttgtctat tatataaaaa tctataaaag aaaagcagtc
    24601 aatcatttag attaactgct tgtacatata tcttattaaa ctgtataaac tataattttt
    24661 attattctcc attttcatcc caagtcataa atccccatcc actatctgga taaatatcga
    24721 tagacttttc tctaatcata taaccaactt tataacactc ttttgttatt ttattagata
    24781 gtatacatcc ttctccattt atctaattcc atttaattaa cttttctttt caaccttaac
    24841 ttttataaaa tcatcttttt taataatttc atacttattt tctcttcaac atcatcaaat
    24901 gagggtgtct caaaattaac tttttacttc ataaggcact cttttttgta tgaagtaaaa
    24961 tatattttca tcatttcaac aataagtaag aggcttatct ctattttgag acagccccat
    25021 ttgatggtgt tgaacattta aataaggttg aactcgtttt atctctcttt ttaagatatc
    25081 tgtaaatttg cacataaagt ctcttcttct tttacaattc taatagtttt attaaagcca
    25141 aagtatatat ctccatattc tttcgtatat gatttattgg tactctttca tctactccat
    25201 gaccaccagt tttatacgct aagaacttag gtccaaacgc caccatatct ttaaaccaac
    25261 ttgcatatgt gccaccaccc atagcaattg tatatccatt ttcatctgtt acttcttcat
    25321 aggcttctaa taatttttta agtactaaat tactctcatc cacataatgt aagtctttat
    25381 gaacaataac ctctattttc caaccattac aaaaaacctt tttgaatcta tctattatat
    25441 tgtttaaaac tatattttta ccatacctta tatctaactc acatacgatt ttttcctcat
    25501 ttacttttaa tattcctaaa tttaaggtag tgtttttgaa tacctcatca tattgattaa
    25561 tccccaatgc atctccataa taatcactac aaaggtattt tgaaactaat tctatatctt
    25621 ctctatgctg aaaatccata ttatcctcaa ctatctttat taccatttta gatatagcat
    25681 tttctccctt ttcaggatta cttgcatgta cagctactcc tttagtagtt aactctgaaa
    25741 taattccatt aataattttt gcagtacaat gagatggaac aacattttct ttagttcctc
    25801 cacttactat tatgtaaggt ttacttttgt caattttaat ttctttttct atccttatat
    25861 gaacccttcc tttttctcca ttaaccactg gatacatagc atctggagta aatcccatac
    25921 ttggaatttc ttcaccttta tctaagtaat atttgataca tttcatacct gtctcctcat
    25981 ttgtaccaaa aattaatctt attcttttat taattgtagg atacatatcc tctatgtttt
    26041 tcaatacatg tataagcata gatacagcac ccttattatc tatgacacct cttccataaa
    26101 taatattgtc aattactgct cccgaaaatg ggtctacact ccacccctct cctggtggaa
    26161 ctatatctaa atgcattgga atccctatta attcctctcc ctctccaatt tctgcatatc
    26221 caatataatt atcaatattt ttaacactaa aacctaaact agcacagtaa tctaaagttt
    26281 tatctaaaga ttttttaggt cctataccaa aaggacattg tgaaataggt tcaccttgtt
    26341 gtgaatcaat ttttatcaat tcttttagaa attctatggt tctatttaaa ctattatcta
    26401 cacttctgct tatatccata aatcaaccta ctttctatct ttttaaagcc tgtccttgaa
    26461 gaacaggctt ttagcattaa aaattatttt tttgtaaata ctaattcaca aacttcatca
    26521 tcatgagcac atttttgagc aaaatctaat ttaacacctt gtgcacagtc aactcttcca
    26581 taatccccat aacaagctaa tctacaaatt tcttttcttt cttctttagt taatccatat
    26641 tctttccaag cagcatctaa tggacagtga tggaatttta aaacgccatt ctcatctgta
    26701 ttttctacta attccatttc aaacactttt tgtcctttac tgttatataa catttctgcc
    26761 atttttcctg gagtatctgc tacgttatat ttttgacctc tcattttacc aaatccatat
    26821 attgcttctt tacatatatc atctggatta gctcctaatt tttcagcttc tttcataaga
    26881 agatagaacc atactgctct ttctcctgtt gctcctctaa ttccttctaa atattccttt
    26941 tctgtataca ttttttctga catttctttc tcctcctaaa attaaattct atattttaat
    27001 cactgtgaat tagaatattc caatgaatga ccctaccaat gctaatacaa ctaaaattac
    27061 taataactta gttattgtcc acttcttgta tttcattccc caatatacga agaatacaac
    27121 accaagtggt aataaacctg gagcaatcat atttaatgta tcttgaacaa caattgcttt
    27181 accaccaata tcaaatgata gcggagttga aagcttaact gtagttgcag ataatgctcc
    27241 catcataaac attcctagaa ttgaagcacc atcaattatc ttattgacaa taccacctga
    27301 tagaattttc ttaattgaat ctctacctaa agaatatcct aaatgaaata agtaataacc
    27361 ttcgcaaaat agtaatatac taaacattat tgggaaaaat gcacctataa cacttccttc
    27421 tgctccaaat gaagcaccta aagctaagaa tattgtttga aatgtaccaa aatctaaagt
    27481 atctccaatt ccagccaaag gtcccataag accattctta acacctgaaa taacttctcc
    27541 tgggattttt ccttcagtag ctttctcttc ttccatagct aaaactgtac cgtgaattaa
    27601 tcctccccat atagcttgag tattaaaaaa ttgtaagtgt ctctttaacg catctactaa
    27661 atcttctttt ctcttatata acttttctaa agccggagtg aaacttgcac aaactgctaa
    27721 tgcttgcatt ctttcaaaag agttggataa ttctgctgtc caccaccatc ttagatatgt
    27781 ttttgttaca tctttctttg taagtactct tgtcttatta acttcagttg gaccttgtcc
    27841 atttttaact tctttatttt ttatttcttg cattatactt cacctaccct tttgtcttct
    27901 ttcataaagg taattaaaag agctatacaa acaccaaata ttgcagctgc agtaattgat
    27961 atttcaaaat attgaaccat aaaaaatcct ataataaaca ttggtaaaaa tttattttta
    28021 cctatagtaa atattgttgt tgcaaaacct aatgcaggta atataccgcc cattactgtt
    28081 aatccattca ttaaccattg tggtataaca tctaataatg attgaactaa atctgctcca
    28141 aaaaagttac atacaaaaac tattggaaac cttaaaacaa acccaaatat taaagaataa
    28201 agtgttgcac atctccagat gccttttgta ttaccttctt cagcatactt atctgcctta
    28261 tgaaccaata cagcattacc agttcttctt aagttattaa ctaatactcc tataacacct
    28321 aaaggtaccg caatagatac tgcaacttct gcattaacac cagtttgaag tgctactggt
    28381 attgcaataa gagcagctag acatttatct gatggaatat ttccccctgc tgcgaccatt
    28441 cctagataaa ccatttctat acttgcacca acaatcatac cagttgttac atcaccccaa
    28501 agtaatccaa ggctaaaacc tataaataaa ggagacttta gtgttgagaa aagggtatac
    28561 cctgcaagac ctgctgcaaa ccaataccat aatcctgtta caattgccaa catcaaaaca
    28621 gattccattt ataattcctc ctaatttata ttttttattt aaatttcttt aacgcatttt
    28681 catatgtcat agatgattcc tctggtataa cttgtaggac tatttcaacc ccattttcat
    28741 taagttcatt aagttgttct acatcctcat ttcctaatga aacagctgta aacaccattt
    28801 tctttcctgc ttcatttgga atacctccta attgaatctt ttcatattta agtccagctt
    28861 tataagcctt atttgccata tcaacatttt taaatagaat aaatatattt ttatctccta
    28921 aagtgttgtt ttggaatgct tgtcccgcat cttctgctgt taaaataact acttctactc
    28981 ctgatggtgc tgccatttta tatatgtcag ccataaattc atcttgacct aagaagtcat
    29041 caactattat tattttttga gcttgagcga tttttaccca ttttgttata acttgcccat
    29101 gaattaatct gtggtctact cttactaatg ttatttttgc cattatattc acctcataat
    29161 ttatattttt ttaaattctt taattaaatc cacacaaagg ttattatttt ttttgacgat
    29221 tctttctggt aatgtatgta atttatcttc tttgcttaat tcttcatcta cgattaaaat
    29281 tgtctgtaag ctaagtccat ttattgcatc tattcctctt cttatagcaa cagctattgc
    29341 gacacttgat gtagatcctc catataaatc tgatattata attttcacat cttctttatc
    29401 tactacttct tcaacctctt tcataaatac agaaacatct ttttcagaac ttagtgataa
    29461 aacttcatat tgatttgaca atccaaagtt tttatttgtt tcttctacta agacttttcc
    29521 ccaagttcca tggcacagta tgattacctt atatttattc attgctaaat aaactctcct
    29581 ttatagcgat taatattttg gtttaattct acttcttctt catcaggtac catttgaatt
    29641 gatacattaa tattcttttt aataaattca tctattaaaa gaaactcttt tttattaatg
    29701 tatacatttt gagatatttt cttttttcct attcctgtag gtattcttcc aacaataagt
    29761 tttttgatat taatcccttc ttctatcatt ctatttgcag tatctaaatt tttaattaat
    29821 acaaaaacgt tatcatcagc ttgattatta taaaaatatc tccttgattc acttacagtt
    29881 aatatcgata aatcaatatt ctttggtgct gccattttta tcaaaccttt agcaataaca
    29941 tcattggttg tttcatcatc tactactact atctttttta cacctagatg cttaacccat
    30001 ttatatataa cttgaccatg tattaatcta tcatcacatc tgcaatattt tactaaagac
    30061 atttttaatc aaactccttt ttctattaca ttgagctaag aactttatta atattgttta
    30121 taccagtttg tcctgcttca atacatgctt ctgctaactc ttctaaactt tttccctctc
    30181 tattaattaa agcttcaagt agcattggaa gatttactcc agtaagtgca tgaaacttgc
    30241 cacctttttt aaggtttaaa cttgcaacat tacttggcga acctcctaat aggtcagcta
    30301 atactaaaac tccgtcacct tcatctaatt catttaactt ttctacaaaa tttttattta
    30361 agtcttcaat attatcattc ctatttagtt taattgctgc tgttctttct gctggtcctg
    30421 caataagttc acagcttttt ataatttctt cactaaaact cccatgagtc ataactatta
    30481 ttcctatcac caatttcacc tcacttttct tgtcactttt tatataagca attgccgtgc
    30541 caacttatgt gtatcaataa caaatggcta ttttacagga tttaatcaaa actttttact
    30601 caattttttt taaaaactta ttatttctat atgtatcaaa agattttttc aacctgtatc
    30661 aaatctgtat caaaaaaagt aaaaaaaaga tagccttttg gctattttta aattttgtat
    30721 caacttttga atttatctgt atcatattgt gattcaaata tatctaatat atttgcatat
    30781 tccatatctg aaataattat atcgaatgtc tcttctacta gcttaaaact ttcttttata
    30841 actaaatata attctttatt tctactaatt ctttcttcat atgatttata aactaaagac
    30901 tcttttatta ttactctttc aatcatacat gaacaatgaa atataaactt tactaaaagt
    30961 tcatcttgaa ttactaaaga atagtgttca ctaattctat taattacttc ttttaatata
    31021 aaataagcct tttccccatt taaaaaagtc aaagttttac taatattatc aattagtaat
    31081 ctatcaaaat atctaccacc attatctttt tcagcatatg taacttccat atctccataa
    31141 tgtttcttta tagattctat aatattaaaa tataatttct ctaatgtcat ttctggagtt
    31201 agagcctttc tagttgcttc tattacaata ggtgtactta ccatatctat tgcttttact
    31261 tcttttcctg tagcatcacg aataacttta gcaaatgtta aaatagaccc catatcagtt
    31321 aaaattaaaa ttccttttcc tttatcaatt ttattggcta tttctacagc ttgtactaaa
    31381 atatcctgaa ctctatcttc taatcccata ttaattgcca ctgcatggtt acaatccagt
    31441 aaagtattgg ctacattcac catgctagat gctgtagatt caccatgcat tatgactaat
    31501 attgctatac tctcctcatt taatcccaca tacgataaat aaagaaatgt tgctaaaaaa
    31561 attgcttcat cttctggaaa ctctactcca tacattaatg acatgttaga taatatttct
    31621 tttgctatgt tatattcata tgctctttcc ttcataattt catctttatt aggatgcttt
    31681 actatatttc caatctttat tctttcaatt aaattctgaa tatgtaaagc tatagctttt
    31741 attaatttat ctaatccttc tcttttgctc catttatcat gcttttgtaa aatatatttt
    31801 acagtagttg caattgaatc attaacaatg ttgttataag ctgtttgatt actactatta
    31861 tatataaaag tattcattaa attataggaa tacttctgta tgtctccatc tataacactt
    31921 ctaatttgtg actctttaat accttcttgt tgaagtttat tccaagtttc ttttatcatt
    31981 ccataaaaat ctaaatcata ttttttattt tctattaata aattttcact ttcaaaatcc
    32041 ttttcttctg gtaaaaaaat aatatcatct tttccaataa aactgaaatt ttgtacaaac
    32101 tcctcttttc tattatttcc atataatgat tctctaatat tatttggtag aagagagagc
    32161 cttacatata cacattccct tttataggtc atataatcta aaaaagctct tgcacaaatt
    32221 aattgtatat cgctttttaa ttggcctatg tttcccttac acttatataa aataaatgcc
    32281 ttaataactt cttttgaaac ctttaactta acaccaatcc taacactctc ttctttaaaa
    32341 aaataacata taagcttcat tctctcttga aagcctcttt cctctaaaga cggaatcttt
    32401 atagttacag gtattcttct taaaaacgtt tccaacattg ctgtttctgg gtcttctgta
    32461 gtggctgcaa ttatcataac tctacactcg tgtaccttat tagcctctcc taaccttcta
    32521 tatatccctt tatccataag cagaaatagc atttcttgtc cctctgcaga taatctatga
    32581 acttcatcta aaaacaatac tccattatta gcttcatgta caataccata cttatcttta
    32641 tcagctccag taaatgctcc ttttacatat ccaaaaagct gcgctaataa taattgctga
    32701 ttatcagaat aatcagcaca gttaaatatg ataaatggtg cattatcact atcttctttt
    32761 atagttaaac tatacttata catatattct gcaaatatag atttaccaac tcctgtaggt
    32821 cctattatta atgtactcaa ccccttaggt ggatatatta ctgctgcttt agcctgttct
    32881 atttgggacc ttaaacttcc atcacatcct actaaattaa aaatattgtt ctcttttttt
    32941 atactctcta aaatatactc atctttgata gaatcatttt cactatattc gtttatagag
    33001 ttaatattat caaatatccc tttatttagt ttctttccta aaatactctc aatactttct
    33061 ttatataagt actgaacagg cttacccttt atctttataa taatactttc ttttattaat
    33121 tgatttaatt ccttactagc attacttcta tttataccta cttcagtagc tatatattct
    33181 gcatcaaatc caaatctaat gccattatta aagttcaagt gttcttctgt taaccttttc
    33241 aagcaaatta aaactttttc tttccttgat agcttctttt gtgtcatagt taacctcccc
    33301 tataagcagt aatactgtta aacatttatt attaagctta attctacaat attttaatat
    33361 ttttgtctaa ttatgtaact attgattttc tttcctattc gttttataat ataaattacg
    33421 ttaccctcat cttttataga ggaggaattt atatgaattt tttatcagat ttacacaccc
    33481 actctatagt cagtggtcat ggctatagca ctttactaga aaatattaat tattgtaaag
    33541 aaaatggaat taagatacta ggtacatctg aacatggtcc taagatgcct ggttctcccc
    33601 acagatggta ctttcacaac attcaaaata tcccaagaat cataaataac attataattt
    33661 taagaggctg tgaagcaaat atactagata ttaaaggaaa catagaccta gagccttttg
    33721 taattcctcg cttagattat cttattttgt catttcacga agctgtgttt tctccaaata
    33781 cattagagaa taatactaaa gctttaataa atgcaataaa taagcatgat aatattgaaa
    33841 tattaggaca ccttggaaac ccaaactacc caatcgacta tgaattaatc attaaattag
    33901 ctatagaaaa gaatatctta atagaaataa ataattgttc tattaaaggc gtgtcaagaa
    33961 atggtagctc ggataactgt aagtatattg ctacactttg caaaaaatat ggtgctaaaa
    34021 tcatactgac ttcagatgct cacatttgtt ttgacatagg taactatgag tattctgaaa
    34081 atatcttaaa ggaaattaat tttccagatg aattaataat gaattatcct aaaaaactta
    34141 ttaatcattt tcaccaaaaa ggtaaattac tagatgttga ttatacaaat atctaagtaa
    34201 taatacatgc ttactttaac tcccataaaa attttaatac tatttatatt atatgaaata
    34261 aagaaattat aataaagaag ctatttaata aagcttaatt acttttatga acttgatgga
    34321 ttgatatggt ctatgatagc aatagaaatt ataacatttt taataaactt agttttatat
    34381 accttatagt ataaatctaa aaaagcatca tctaaaaagg agctgtcaca tgagcaaatt
    34441 aaatttgttc tatgatagct ctttttttac ttattttaat taggtatatt tttaattatt
    34501 ttatataaag cttatgttct aagtaaaatt atgcataaca aacaaaggta taaaaatacc
    34561 attttttcag ataatattta attataaata ataaatttag aatacttctt ttaaatgatg
    34621 agagtctaga aatttttatg tgtattcttt aaataaaaat ttccagactc tagccccttt
    34681 ttgaatatt
//
LOCUS       DAGQVA010000045        34475 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.045, whole genome shotgun sequence.
ACCESSION   DAGQVA010000045 DAGQVA010000000
VERSION     DAGQVA010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34475
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.045"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(143..1837)
                     /locus_tag="MIV85_002266"
     CDS             complement(143..1837)
                     /locus_tag="MIV85_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBY2961598.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     gene            2330..3151
                     /gene="yidA"
                     /locus_tag="MIV85_002267"
     CDS             2330..3151
                     /gene="yidA"
                     /locus_tag="MIV85_002267"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBY2961599.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            complement(3288..3437)
                     /locus_tag="MIV85_002268"
     CDS             complement(3288..3437)
                     /locus_tag="MIV85_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961600.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSNDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(3444..3929)
                     /locus_tag="MIV85_002269"
     CDS             complement(3444..3929)
                     /locus_tag="MIV85_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961601.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            complement(3942..4694)
                     /locus_tag="MIV85_002270"
     CDS             complement(3942..4694)
                     /locus_tag="MIV85_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961602.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            complement(4871..5500)
                     /locus_tag="MIV85_002271"
     CDS             complement(4871..5500)
                     /locus_tag="MIV85_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961603.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            complement(5461..6024)
                     /locus_tag="MIV85_002272"
     CDS             complement(5461..6024)
                     /locus_tag="MIV85_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961604.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            complement(6034..6258)
                     /locus_tag="MIV85_002273"
     CDS             complement(6034..6258)
                     /locus_tag="MIV85_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961605.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            complement(6263..7354)
                     /locus_tag="MIV85_002274"
     CDS             complement(6263..7354)
                     /locus_tag="MIV85_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2961606.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            complement(7389..7847)
                     /locus_tag="MIV85_002275"
     CDS             complement(7389..7847)
                     /locus_tag="MIV85_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961607.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            complement(7840..8925)
                     /locus_tag="MIV85_002276"
     CDS             complement(7840..8925)
                     /locus_tag="MIV85_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBY2961608.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            complement(8952..9137)
                     /locus_tag="MIV85_002277"
     CDS             complement(8952..9137)
                     /locus_tag="MIV85_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961609.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            complement(9299..9631)
                     /locus_tag="MIV85_002278"
     CDS             complement(9299..9631)
                     /locus_tag="MIV85_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBY2961610.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            complement(9887..10723)
                     /gene="nadC"
                     /locus_tag="MIV85_002279"
     CDS             complement(9887..10723)
                     /gene="nadC"
                     /locus_tag="MIV85_002279"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBY2961611.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            complement(10704..12005)
                     /locus_tag="MIV85_002280"
     CDS             complement(10704..12005)
                     /locus_tag="MIV85_002280"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBY2961612.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            complement(12018..12932)
                     /gene="nadA"
                     /locus_tag="MIV85_002281"
     CDS             complement(12018..12932)
                     /gene="nadA"
                     /locus_tag="MIV85_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBY2961613.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            13350..14807
                     /locus_tag="MIV85_002282"
     CDS             13350..14807
                     /locus_tag="MIV85_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBY2961614.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            15030..15458
                     /locus_tag="MIV85_002283"
     CDS             15030..15458
                     /locus_tag="MIV85_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961615.1"
                     /translation="MNNKLHELEKNLPEISCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            15518..15826
                     /locus_tag="MIV85_002284"
     CDS             15518..15826
                     /locus_tag="MIV85_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBY2961616.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(15973..16995)
                     /locus_tag="MIV85_002285"
     CDS             complement(15973..16995)
                     /locus_tag="MIV85_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBY2961617.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(17170..17676)
                     /locus_tag="MIV85_002286"
     CDS             complement(17170..17676)
                     /locus_tag="MIV85_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBY2961618.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            complement(17736..18437)
                     /locus_tag="MIV85_002287"
     CDS             complement(17736..18437)
                     /locus_tag="MIV85_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961619.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            complement(18655..19725)
                     /gene="buk"
                     /locus_tag="MIV85_002288"
     CDS             complement(18655..19725)
                     /gene="buk"
                     /locus_tag="MIV85_002288"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBY2961620.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            complement(19778..20353)
                     /locus_tag="MIV85_002289"
     CDS             complement(19778..20353)
                     /locus_tag="MIV85_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBY2961621.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            complement(20355..22142)
                     /gene="iorA"
                     /locus_tag="MIV85_002290"
     CDS             complement(20355..22142)
                     /gene="iorA"
                     /locus_tag="MIV85_002290"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBY2961622.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            complement(22203..23462)
                     /locus_tag="MIV85_002291"
     CDS             complement(22203..23462)
                     /locus_tag="MIV85_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBY2961623.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            complement(23724..25724)
                     /locus_tag="MIV85_002292"
     CDS             complement(23724..25724)
                     /locus_tag="MIV85_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2961624.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEIVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            complement(25732..27618)
                     /locus_tag="MIV85_002293"
     CDS             complement(25732..27618)
                     /locus_tag="MIV85_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2961625.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNETRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            complement(27645..29486)
                     /locus_tag="MIV85_002294"
     CDS             complement(27645..29486)
                     /locus_tag="MIV85_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2961626.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            complement(29617..30036)
                     /locus_tag="MIV85_002295"
     CDS             complement(29617..30036)
                     /locus_tag="MIV85_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBY2961627.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            30349..30531
                     /locus_tag="MIV85_002296"
     CDS             30349..30531
                     /locus_tag="MIV85_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961628.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            30860..31882
                     /locus_tag="MIV85_002297"
     CDS             30860..31882
                     /locus_tag="MIV85_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBY2961629.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(31975..32577)
                     /locus_tag="MIV85_002298"
     CDS             complement(31975..32577)
                     /locus_tag="MIV85_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBY2961630.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(32594..33742)
                     /locus_tag="MIV85_002299"
     CDS             complement(32594..33742)
                     /locus_tag="MIV85_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBY2961631.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            complement(33735..34112)
                     /locus_tag="MIV85_002300"
     CDS             complement(33735..34112)
                     /locus_tag="MIV85_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2961632.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
BASE COUNT        11339 a         5904 c         3641 g        13591 t
ORIGIN      
        1 attttctttt ttttttaagt acaaatcttt tttagtttat tttatcaatt tagttaaaaa
       61 caagactatt ttcacaacaa ataatcactt tttatatatt ttttaatttt tcacttttat
      121 acaataaaat tctcataatt ttttataatt tgctgtcatt tatttcatca aaccaagatt
      181 taacatcacc tataatagac tcaatacagc catcatcaaa tggagaatac aaatttccca
      241 tactcacaat atctaaaaat gattttgttc ctccaacttt acagatattt atataatctt
      301 tccatcctgc atctctatct tgaatcattt ttttccaaaa ttgtaacgca caaatttgag
      361 ctaatacata atctatataa taaaacggat ttttaaatat atgtccttgt ttaaaccacc
      421 aacaacctct ctctaaaaaa gaattatcac catattttct atgaggtaag tattttttct
      481 ctaaaaatct ccagatttct tttcgttttg acttatctac attaggattt ttgtaaatat
      541 agtgttgaaa ttcatcaaca attactccat aaggtataaa tttaattgaa gatgataagt
      601 gagtgaattt gtacttatct gtatcttctt taaaaaataa atccatccac ggccatgtta
      661 taaattccat actcattgaa tggatttcac aactatcaag cgttggaaaa ttaatttctg
      721 gcatatcaat ccatctagac atatacaact gaaatgcatg tcctgcctca tgtgttaata
      781 catctatatc atcagcagtt tgattaaaat tagaaaaaat gaatggtgac ttataatctg
      841 gtatataagt acaataccct ccagctcctt ttcctttctt cgtttctaaa tccataagtt
      901 cattttctaa cataaaatca aaaaattcat ttgtttcttt tgacagttca gaatacatcc
      961 ttttaccatt tttaattatg tatcttgaat ctccctttaa acttgcattt cctgttaaaa
     1021 attccacgcc ttcatctatg taacttaaat attctagacc aattctttta gcttgttttt
     1081 cataaagctc atttgccatt ggaacaacat attttagtac ttgttttcta acatttttta
     1141 tcatatattc tctgtagtca cttctcatca ttctaacata cccaagctct acaaaatctt
     1201 caaaacctaa ttttttagac atcttatctc taagtttaac caatttatca aatatgtcat
     1261 caaatttagt ttcattttct tcaaagaaat tataatatgc tttgtttgct aattctcttg
     1321 tttttctatt cttagaatac atgaatttcc ccataccaga taaatttctt attttcccat
     1381 caaacattat ctcagctgaa gctaaaagtc tagtatactc tgaacacaat ttattttctt
     1441 cctgcaattc acttattatt tctttggaaa aactttttaa agaatactct actattgtga
     1501 aaaattgctc tccaaactct tttatcaaat catatttaaa ttttgaattt acaatggcat
     1561 tataaaaata tgaatttaat tcttcataca aaggcatata ttcatcccaa taattttttt
     1621 cttctttgta gaatttatta aatgtgtctg tactatatct tatcgaagct atatttgaca
     1681 acgtttctat tttatttctt aataaattaa tcttatgtat atttttttgt tgctctttat
     1741 aattacgaga attatttata tcttctacac aactcaaaaa ctcttttttc atactattat
     1801 aattgggtct ttcatactta aactctgaaa acttcattta aagcactcct ttacaacttt
     1861 actttattgt atttataaat atagatttac atgtactatg taatactctt ttataaatta
     1921 ttatatatat caaatattct ttatattata atcatgttga ataataacat atgattaatg
     1981 gaattacaat attttataac acaaaactaa ctaatataac aaattaccat cagtctattt
     2041 attcaaactt ctaactatat aatatacatt tatttatatt aacaatgcaa acgataccat
     2101 tatttgtaat taagaatttt ggaattattg attacaaagt ttttacattc tcatctcaca
     2161 taagtaatat ttttatcaaa aaattaatat tattaaactt tctaaattac ttatctcttg
     2221 atataatagt atacaaaaca aaccatattt cccactgaaa ctttgttcaa cactagctgt
     2281 gtcaacgttt tcacaggaaa tttgagtata taatttattg gaggttgata tgtacaaatt
     2341 aatcgcacta gacattgatg gaacaatatt aaatacacaa aaaaggatta ctcctgaagt
     2401 ctttgagtcc attcaggagg caaaaagggc tggggcaaaa gtagttataa caacaggcag
     2461 acctcttcct ggtgtaaaag aacttctaaa tcaactaaat ttaacagatg aaggtgatta
     2521 tgttatatgc tttaatggag caattattca agaagttaaa agtgagaaaa tcatacatga
     2581 tgtagaaatg agtttagatg attttgattt tatatataat aacgtttgta aaaaatataa
     2641 gactaaaata cacataaata caatgacaaa tttaattaca ccaaatgaaa cgcctggcaa
     2701 atatacactt catgaagcga aattaaataa tatagaagtc aaatatatac aaaaagataa
     2761 aattgatgaa tctattaaaa tctgtaaaat tatgatagtt gatgaaccag aaagattgga
     2821 agaaatcata cagcaactac ctaaaaattt attcaataaa tatactatag taaggtctgc
     2881 tcctttttat ctagaatttt taggtaaaac tactaataaa ggaactgctc ttaaaacatt
     2941 atgtacgaat ctaaatatac ctatagaaaa tgctattgct gttggcgatg aagaaaatga
     3001 ccaacatatg ataaagtatg caggtcttgg tgtggctatg gggaatgcac gtaatagtat
     3061 aaaggaaatt gcagattatg ttactgatac taataatgaa aatggagttg caaaggttat
     3121 aaataaatat atacttaata aggctatcta atcatctaaa aaaaactaaa aatatacctt
     3181 tagatttaaa tacttttcac atccctactc tatactaatt tatatagtat ggatattacc
     3241 tatcattttt atctaaaggt catttttagt ttttcatata tgtatatcta tgatagtacc
     3301 ttttgtttga gtttaaatat tttatatgat tctactattg cctcattaat atctaaacaa
     3361 tatatatctt catcattaga taatcccgct tcgtttgtcc aagcatcaaa atcactcttc
     3421 gtccagaaga aattcattat atttcagcaa ctagcagccc aatttagatg cttatcaaga
     3481 tttatatgaa gcactcttaa gtttggatta ttcacatact caatcttttc attttttata
     3541 attacttcta tttccttacc tgtagcacta caaatagagt ttatttttat atcttggttg
     3601 aatgtgcaag aggttcctat agcatctata gcacacattg cactgaaact tctattatct
     3661 ctcaaagtta ctttatgatt tgttggcaat gctgatacag gatatataaa atttatacta
     3721 ttcccatcaa caaccattat atttttataa ataaaatatt gtagtgtcct ttctatatat
     3781 tctttttcta tattcaactt tttacttata tattcagtca cttcttgaag tgtaacacta
     3841 gaacctttat ctattatcat atccataata gagattctta ttttctgttg tgtattatcc
     3901 aaactattgt atttttctat ttgactcatg tctactcctc tttaaacttc ataacacttt
     3961 gataaagtat cagttaattt gtttttgtac tcttcatatt tttggcttcc tctaattcta
     4021 ggtcttggaa tatctatatt tatatcatca ataattcttc ctttatctct cgacattact
     4081 ataactctat cactcatata tacagcttca tcaacatcat gagttaccat taatgcagtt
     4141 attttcttct ttatccatat tcgttctagc tcttcctgta aattttgtct catttgaaaa
     4201 tctacagctc ctaatggttc atccattagt aatacctctg gattacatgc taaagctctt
     4261 atcatggcca ctctttgttt cattcctcca gataattgat gcggaaacag tttttctttt
     4321 cctttcaagt ctgacataac caaaagttct tctagcattt cttctctttt ttcttttggt
     4381 attttctgct gtttcatagg aaatagaaca ttacctctta tagttttcca aggaaataaa
     4441 gcataatttt gaaatataaa agctctatct atgcccggtt ttttaactct tttatcattt
     4501 ataaaaacat ctccacgttc tgatttttga aacccaccta ttatagtaag taaagttgtt
     4561 tttccacaac ctgatggtcc taaaagacag acaaattgtc catcatctat atccatactt
     4621 atatcttcta aaacctttgt atgtactcta ttatttacaa atgtcttatt tatatctctt
     4681 acacttaact tcattaatct gcaaacctcc atctacaaag gattttattt ataaacttta
     4741 ataccctatc tattataaat cctattaaag ctgcaaatat cataagccca attaatacat
     4801 ctgtatgcat taatgtttga gcttgtacca ttgagtaacc gagaccggca ctcgtagcta
     4861 taaactcggc tcagataaca gacatccatc ctgtacttat agcaatcctt gaaccagtta
     4921 gtatatctgg aagagatgcg ggaacaatta catttgtaaa tatcacaatt ggcgatgctc
     4981 ccatacttct agctgcatta taataatcct ttgatattgc tcttactcct tgaatagtat
     5041 ttaaaattat agggaaaacc cctgaaaaag ctattaaaaa tattgttgga ccatctccta
     5101 taccaaacca tactatagta agaggaaccc atgccattat tggaacttgc cttacagaat
     5161 ctactactgg agataaaacc ctttcaaaag ttttagaaaa tcccataata aatcctattg
     5221 gaagcccaaa caataatgca tacataaaac ctttaagtac tctctgcaat gttataaaaa
     5281 gattagtgac tgtctctgca tctgtcacac agaaaaagaa accttttatt acatctactg
     5341 gcattggaag taacaaagaa ctccctatat cttttgctgc aaaatgccag actaaaaata
     5401 taataactaa tagtattatt ttatataaaa tatccatact accatcagtt tttttcttag
     5461 ttaatctatc gcttttatct ttagaaattt taatttccaa ttgcttattt cctccatatc
     5521 tatatttctt atattcctgt actcttttaa tgctttctta aatgtagctt tattctttaa
     5581 agcatcaaca cttttattgt aaagtgttat aaaatcacta tatgctttac tttttttaaa
     5641 ctctttactt acaactaata cataggtatc ataatctcct aatttagttg tagattttct
     5701 tttgccctct aacccaattg actttatgca atctattaca acaccatcta ctaaattact
     5761 ttctaatcca tatgctagtg cagtccctaa taagggagct acttccacat tcttgtagta
     5821 ttttttaacc aattctgact ggtaatctct attttgaatg actcctatct tttcaggatt
     5881 attatcactt aatagaaata tatcagaatt ttgaactaca gtaccaacaa tttcaaatcc
     5941 actatttaca tttacatatt gttttgcagc atctttacat atgattgcta tatctatttc
     6001 ctctgaactc agagcccact gcattgtact tgctcagcaa tcattaattg taaaaatatc
     6061 cattatatca cttactttta tattttcaaa gtagtctcta tttaccatat aatttattac
     6121 aaaaccagag gtatcatcag atacccctat tcttaatttt ccttttattt cttctttatc
     6181 ttcaaaatta aaaaatatta taaatatact tcccaaaata atgataaaaa gtattattat
     6241 atttttcata ttctccattt atttataata cctttgcttt ccagtcttca taactcatac
     6301 cttcaggaaa ctctgggtta actttttctt ttataaattt gtcaaaatca tcagctccac
     6361 aagagtccaa taagcttgta tcaatcgtat cttcatattt aggtatatca tctaaagcct
     6421 ttaaatcttt atacatttgt aaattatttt tatattcttc acctgtaact ttccaagtaa
     6481 gagttctacc ttctccaaca gtcttcttat agatagttct aagtgcaact tcttcttcta
     6541 cattataata ttttgcaaat attttagctg cttcagctgg atttgtatat atatattcta
     6601 ttgcttttgt atgtgctaga accaattttt ttgctaaatc tggatgttct tttataaagt
     6661 ttttgtttaa tgagaatgaa caacagttat attctttgcc attagctttt tctttatatt
     6721 gagtagatgc tattattttt cctgcaccgt cattttcagc tacagaaccc caagggtcac
     6781 aagatgtaaa agcttgaatt ttcccagttt taagagctaa atatttatct ttgtctgaat
     6841 ccatatttac aacttcatat tttgatgggt cagttggtag acctgtttct ggaccataat
     6901 cacttgtcca taagaaatca ctcatatctg ttgcaatttt tttacctatt aaatctttag
     6961 gttcttttat atcttttgaa actattaaat attcagaacc accagtatgg ttgttagctg
     7021 ctattgttat tggtgaaccc ttaggtattg ctccaactaa ccccttagtt cctatgtaac
     7081 ctgcatccat ttttcctgct gccatagctt caggaacttt accatttcca acagttttta
     7141 cattaagacc taaatcttta tatattcctg ccgattctgc tactggtccc gcagtcatat
     7201 ggtcacaatt ataataacct actgttattg tataatcatc ttttccagtt tttgcttctt
     7261 ctttttcttt tggtttacta ctacatcctg ttaatataga tgtacccatt acaccaaata
     7321 agattaatgc ttgaatcttc ttagataatt tcatataaat ttcccacctt tatgtattat
     7381 ttttattttt agcaacattt gtccatatct tcgccaaata aatcaacaaa ttttttaccc
     7441 tctactctgt aaatagcata tcctacatta ccatttttag accctgatac aattacttct
     7501 attggtgctt tatcatcaat atttttaaag gttatagttt gattctctat aggtgctggt
     7561 attggctttg ttatatagtg gctattttta tcagaaacta cgactaccat ttcatttgaa
     7621 ttattgcttt ttttatatat aactactaaa tcttttttcc catcattatt taagtcttct
     7681 tcagcacaag ttattatgtc ttctttataa ttttttctaa aatattctaa tgtttcttta
     7741 ttcacatttg gaatagaagc atcttctttg atgttatcat caactatttt tgataaaatg
     7801 attaacacaa ctactatgca ggatattata actatctttt taagcatgat ttcctatgac
     7861 ctctttcatc tttggtatta ttgatttaaa tgcaaataaa ataattaaaa tagtacatac
     7921 atactcaaaa ctatcaggta tatttaacat tagtttattt gccaactgta ttgaagaatt
     7981 tgttgcatct aaatttactg agttattatt cactaaaagt aaatttgtta tatatccaat
     8041 tattattgaa gacagtgtca aagttacaga atatataata acagttcttt ttccaataag
     8101 tttaaacata cttataagtt ctggtagatt tgtagctgct ccagctatta gaaatgttat
     8161 cgctatacca ggagatgctc cacttgcaac aagggctgct ataaacggta tatgtcctac
     8221 agcacataca tacataacac atgcaagtat tgctatactt ccaagagata gcaaacctgg
     8281 atttcctaaa tatttttgaa ttatactatt tggaaaaata gttgttataa atcctgcaaa
     8341 aaccataccc attactacat atttactaat agtaagggct aattcaccaa aagaccattt
     8401 aagaccatca atcatatttt ccataaaact tcttttttct tcttctaatt ctattacttc
     8461 ttcctctgaa tcattatgaa gtgataattc ttcttttcca aaacaatttc ctaaaaatcc
     8521 tactaaaaat ggtactaaaa aaccagctat tagataaatg attgtaactt taggacctaa
     8581 aagacctaga caaagaacta cagctattgg atttattatt ggagttgatg tcataaaagc
     8641 aagtactggt cctaaatatg ctcctgaata atacatactt attccaagtg gtattactcc
     8701 acaactacat attggtaaaa acattcctga gatagtactt ttaattaaag aagaaaattt
     8761 cttatttcca agttgttttt gaaaccttct tggagttaaa acattgtgaa gtacacctgc
     8821 caagataaaa cttatcataa gccatcctga tgctccattc agtgtaacta tagaagctac
     8881 tatagtatct ttaactccat ttaaaacaat ttctaatata ttcatttttg atactcctaa
     8941 tttttaaact tttaattatt gtttatagct tctactattg ccctttcaat tgtatcttta
     9001 tttaatctat catatttctt tttctgattt attattaaag ttccttttgt tataatccca
     9061 tattttttta tatacgaaaa atctttccct gcttgatata attttatttc caatttatca
     9121 gcatactttt ctgacatttt ttttataaac actccatgtt catcacaaga tggtcaagtg
     9181 tttataaatt caactaaaat tttagacatt tgttcatccc ctactttaaa caatttatct
     9241 tttacttaaa ataatccaca gaaaataaat ttttctatgg attgtatcct atactaattt
     9301 ataacgttat aacttggtcc acacctgcac tgcctaaaca agcatatagg tttgggaaac
     9361 atccaattgt agctccatca accaaattat tctctatacc tctttctata gcacattggt
     9421 cacaagccat tattatcata tcagtttttt catgtaattt acttagtctc tcgcctacag
     9481 gattaccttt agataaaaat aaggtattat ccataaagaa aaacatccct agaacgtcta
     9541 ctccatgagt tccttgttca agttgtggta ttatcatttt gtctagaatt ttatgtgtat
     9601 tagtactact aaaaatataa gctactttca tttttattcc ccctatactt tttatatttt
     9661 acaaaatttt acagatacaa ttatattata agtttattct tatttatctg taaaatagat
     9721 attaactata ttattaaaag tgtatatagt atttatctat ttttattaaa ttattgattg
     9781 atttttttct atttttatta attttaatga ataaaaaata gactccttaa atttataaaa
     9841 caaatttaag gagtctattt taattaagtt tatttcaata taaaatttat atatttctca
     9901 aattcttcat acttatatcg agagctttaa cagaatgtgt aagcgctcct acagaaacaa
     9961 catccacacc aatttttcct atatcttcta tagtatctaa atttacattt ccggaaaatt
    10021 ctacaatggc tcttccattt ataatatcta ctgcttgttt tgccatttcc aaactcatat
    10081 tatccaacat tattatatct gcattggctt ctattgcttc ttttaccatg tctaaagttt
    10141 ccacttccac ttctatcttt ctaacaaaag aagtattttt tctagctaat tcaactgcct
    10201 tcttaacact accagcagcc ccaatatggt tgtctttaag caatattcca tcagataaat
    10261 taaatctatg attgcatcct ccacctactt tgacagaata cttatctaat attctaagat
    10321 taggtatcgt ttttctacta tctaataatt ttgtatttgt accttcaagc ttttcaacat
    10381 acctacttgt aatagtagct ataccactca ttctctgtaa ataattcaat gctacacgct
    10441 ctcctacaag taagtttcta gtactacctg ttaatacagc tatcttttca cgattcttta
    10501 ctctatcacc atcattttta tataatttta catctacatc accaagtatc tcaaaaactc
    10561 tcttaaatac acctaagcca gctattatac catcttgttt gcaaattaaa tctacagtag
    10621 atttagaatt ttcatccaca atagaattag ttgttatatc ttcacttgga acatcttcta
    10681 tcaaagcatc ctgtatcatt ctatcaataa tcaaataatt catcgccaaa atcctcactt
    10741 gttctttcaa tttcttttat gactaatatt ttattttctt tttttacctg ttctatatct
    10801 atatccatat ctggtacatc tataaactta acttttacat tatctataac tgagtttata
    10861 tttttagctg ctctttttga aaatacaagc ccttcaagta atgaattact tgccaatcta
    10921 ttggctccat gaacacctgt acaactaatt tcaccaactg catataaatt ttccatagat
    10981 gtttttgaat ccaaatctac atgtatcccg cccataaaat aatgttgtgc aggagatacc
    11041 tttatacatt ctttcgttat gtctgttcct ctagctaaac attcattata aataaaagaa
    11101 aatctattaa ttaaatattc actatctaaa tgtgttgcat ctaaatacac ataaggtaat
    11161 ttatcttttt ccatttgctc aaaaatagct tttgaaacta catctctagg aagaagttca
    11221 tccacaaatc tttctttatt tttatttaaa agtttagctc cctctcctct taatgattca
    11281 gatataagca ttctcctacc ttcattattt tcttcataaa aggctgtagg atgtatttga
    11341 atatattcta aattttctat ttttatatta tttcttaaag ctattgcaat tccatcacct
    11401 gtaagatgtc tttgattagt agaattttta aaaagcccac caattccacc tgtagctaaa
    11461 actactattt ttgaaaaaac atgaatctct tttttagatt taaaaattct agctcctata
    11521 catttattgc catcttttaa tatatctaaa agatatgcat cttctataag agttatattt
    11581 tctctagttt tagcttcttt taataaagtt ttaaaaacaa cttctccagt attatcctta
    11641 ctatgaacta ttcgatttac actatgtgct ccttctcttg tgtaatctat ctctccattt
    11701 tctttgtcta aaggcatacc atattctact atctgaccta cattttctat agattcatct
    11761 gcaagtactt gaactgcttc aactctattt ttatactgcc cagccttcat tgtatcttct
    11821 acaaaggatt ctatatcatc aatatttcta gcagttgaaa ttccaccttg tgcaagatat
    11881 gtattgttgt tttcaattgt tgatttcgat actactagca catttaaact tttatctaaa
    11941 tttaatgcac agtataatcc tgaaactcca cttccaacta ttaaaacatc ttgttctaaa
    12001 ttcataagtc tatccctcta tccttctgct aatttgtgca tgttaagcag tgaatttaaa
    12061 gccttttcca tgatttcatc ttctacaata acttcatttt ccatattttt aagtgtacta
    12121 tataaatttt ctaatgttgt ctttttcata tctgtacata gtatttttcc accaggaata
    12181 taaaagtttt tattaggatt atttttcttt aattcatgta atataccttc ttcagttgct
    12241 attataaagt ctttgttttt actattagta gcatatttta ttattcctga tgtactacct
    12301 acataatctc ctaaatctct tatttctttt ttacattctg gatgtactaa tacttctgca
    12361 tttttatact tatcttttaa ctcaattatt tcttcagctc ttatattgtt atggtattta
    12421 caatatccgt cccaaaatat aaagttttta tctggaaatt gttctgcaat atatcctcct
    12481 aaatttttat ctggaaggaa tataatttct ttattatcta tgttttctag tattttaatt
    12541 gcactagaag atgtaacaga aacatcacaa tgtgccttaa ctttagctgt agagtttata
    12601 taacatacaa ccaaagcatt tggatactgt tgctttaatt ttatcacgcc ttcttcatct
    12661 accatatctg ccatagcaca cccagcgtta cttactggca tcaatacagt tttttcaggt
    12721 gataatatct tagcactttc tcccataaac cttactccac aaaatacaac cacttcttct
    12781 ttacaatctc tagcaatctc acttaaataa tatgagtcac caactgcatc tgctaattct
    12841 tgtatttctg gtggttgata aaaatgggca agtattattg catttttttc tttctttagc
    12901 tctttgattt gatatgttaa atctttatcc ataattgcac cgctttctat atgtactagt
    12961 gtatatacac ctgtaaaccc attatatcac ttgactattc tttcttcaag aattttaaac
    13021 ctcttaatat tgttaagata tagacattta tattctcaat tgattttcct tttttctcca
    13081 tctatttaaa ctaattttta tattttttaa tttttttgta aaatattatc agaattttgt
    13141 ttatattctt tattgctata acattgaaaa tattaccaaa tacctgtata ctaagtacat
    13201 ggttatgtat atgtatttat ttctgaaatt atattagttg taatacttta tagaatttgt
    13261 aggttgtcca gaattaaatt caatataaat ctacacattt agataatatg tatacaaaga
    13321 ccaaaaaatt ttataaatgg ggtgatatta tgacaacatt cttaatcggc ttggctatat
    13381 tactaatagg aggtgcttta tatggtgctt attgtgaaaa agtatttggc ccagatgaca
    13441 gaaaaacacc tgcacttgct caaagtgatg gagtagacta tgtcccaatg aaaaaatgga
    13501 aaaatagtct aattgagttg cttaatatag ctggtacagg accaattcta ggacctatcc
    13561 aaggtatatt gtttggtcca atagcattca tactaatacc tatcggctgt gtatttggag
    13621 gagctttgca tgactatatg agtggaatga ttagtataag agaaaaagga gcacaaatgc
    13681 cttctcttat cagtagattt ttaggtaata aagtatttca agtctataat atattccttt
    13741 gtcttttaat gcttttagtt ggtgcagttt ttatttatac acctggggat ttagttgtta
    13801 ctcaaatttt aaatatgaaa tcgactataa ataatccagt tgtctggata gtttatggac
    13861 ttatctttct atattacttg tgtgcaacac tatttccaat tgataaaatc ataggaaagg
    13921 tatatccaat atttggagct attctacttt tatctgctgc tggtgttgga attggaatct
    13981 ttacacaagg ttatgattta gctaatttaa gtcttgcaaa ttggaaaggt attcatcctg
    14041 atggtattcc tcttattcct acattctttg ttacagttgc ttgtggtatt gtttctggat
    14101 tccactcaac tcaagctact cttatagcaa gatcagtttc aaatgaaaaa gaaggaaaaa
    14161 ctacttttta taatatgatg attttagaag gtttaattgc aatgatttgg gctgcagctg
    14221 ctatgggtat ttacaataaa ggaataccta aagaattagt aggttctcct gatgtaatag
    14281 gtttggttgc aagagattta cttggttcta ttggtggtat catagctata ataggtgtaa
    14341 ttgttttacc aataacttct ggagatacag ctttaagatc tttaagatta atgcttgcag
    14401 attactttca ttatgaccaa aaggaaaaga aacatcgtgt tatattgtca atctgtatat
    14461 ttattcctgt catagccatc cttatatttg caaagcttag tgcttctgga tttaatatat
    14521 tgtggagata cttctcttgg agtaatcaaa ctattgccat atttgcattt gcaatgatta
    14581 cagtttacct tataataaaa gaaaagaatt atattataag cttaattcct ggtatgtttt
    14641 attcctttgt tatattcagt tatatattta atgctcaaat tggatttaac ttaaacataa
    14701 atatatcata tgttttagct gccatattta ctgtattata tgctatttta actgtacgct
    14761 ctggtagaaa gttaaaaagc aaagcagata ctaagttggc tgactaaatc taaataaaat
    14821 aatacttaga ataaatttta ttaaaaaatg ataaaaaagt aggcaatctc aagttagatt
    14881 tgcctctttt ttatttaata cagtaataaa tacttaagta tttactcctt attggaatat
    14941 ttatcctaaa tctctaatat aaataaataa aagttttaaa ataatctatt catttatata
    15001 cttaaaataa attttttgga ggaatactta tgaataataa attacatgaa cttgaaaaaa
    15061 atctaccaga aatatcttgt tctttttgca cacatctttc atttaagggg cctagcctag
    15121 actatagata tgatattaga tgtgttattt cagatacaaa gcccgatttt agaggatgtt
    15181 gtgaatattt tgaaccagaa tatacagaat taaatacagg agatttagac aatctataca
    15241 taaactttct tgagacatgc ctcaaggtaa attataatga ttacatcaat tctatgtatt
    15301 ggaagttatt taaagaaaga accctactag aaaacaattt taaatgttct atatgtggat
    15361 caactgaaaa tgttgatgtg tatcatgtta ataaaaattt aggaagggaa acttccaaag
    15421 atgtagttgt taaatgtgat aaatgtaatt gtaaataagt gtataaaatt tagataactt
    15481 cacataataa gtttaaataa aacttaggag gttatttatg aaaaataata atttaaattg
    15541 tgctgctact aattgtgctt ataatactag tggatattgt tatgctggta gtataaaagt
    15601 agatggaatg caagcaacta ctacagaaaa tacttattgt gcttcttttg aagacaaata
    15661 tacatctggt ataactagtc gttctaatga aactaaccaa gttgatacag ataacattca
    15721 ttgtgaagct gtaaaatgta aatacaataa aaatgaactt tgcaaagctg aaaaagttca
    15781 tataaatgaa agaaatgcaa gttgtgaaac ttttgaaatg aaataaattt ctttttattt
    15841 agttttatag tatttataca aagcaaaatt gaacctatca aatagatgtc tttattaatg
    15901 atgtctattt ataggttctt ttttaaaaca attcataatt tatatataaa aataaattat
    15961 tattttaata tattacctag aagtaaattt aacacccaga atatccataa ggaacataaa
    16021 tattggaact ccaattagta atccccatac acctaaataa tgctctccta caagtaaaat
    16081 aataaaaaca aaacaaactg gaagtttagt tctattcgac atcaacttag ggtttaatat
    16141 gtatgtttct actgcatgca ctatacaaat cataagtaaa actccaaaaa cctttgttat
    16201 tcctcctgta ttaaatgcta ttacagttaa tggaatcaaa gacactataa ctcctgctac
    16261 tggaataaga cccaacacaa aaatcataaa tcctaaagcc catatttgag ggaatcccat
    16321 gaaacctaag aaaatcatag aaacaacaga atttataaag gcaatcataa cttgtacttt
    16381 cattacttca ccaaaatttt taacaaagct ctttccaaaa aatacaagcg aattataaat
    16441 aaaagaaatc ttactatcag aaagtttatc tccaaaattt ttaatttcat ttttttcaag
    16501 taaaaggagt aaactcagta aaaatgccaa taatatattt actccaaaac ttccaacttt
    16561 tgttgctgtt gatgctataa gtagccctgc ttgtgaaata tatttattaa aatccagctt
    16621 tgagacaata ggatacaatt tcggtcctaa agattgagca aattgattta catcaaaatc
    16681 actaaaaacc ctactcaact ctgtaagttg aactataatt attggtacaa ctgcatagct
    16741 aatcaatact aacaatatag caaatagtgc atataacact ataattatca atgaatctgg
    16801 aatatttaaa gaagaaaact tcttaattcg ttttcttgtg gctacaagca agttatagaa
    16861 aataaaagtc ataataaatg ttaaaagcac catatttaac atataccaaa atgtaattag
    16921 aataattact acgacagata tagaaacaat tttatatttt gaactgtcac gtgccaatcc
    16981 tttgttatct tccatagttt aaatcctccc caaattttta tgactttata atgactgccc
    17041 tttttatttt aatctcaaaa aacaagtaga aaaatactaa aaataactta ttaattttca
    17101 taaaacaata ttaaaattta gagaagatac attttaaata atcttactta tactgaaatc
    17161 tgctctacat catatattta atttattatt atctatctca tatagcaatt cgtatatctc
    17221 tggatattca aaaaacaaac cctcttttag taattgtctt atttcatctg tgcttaccca
    17281 ctttatatca cttacttctt cctcctgtaa aatagcttta gatatatcat attctttttt
    17341 aactaagtat acatcccaaa gagtatcttc atgaatcata cttctaaaaa ctttcatctc
    17401 atctttagtt atatctatcc ctatttcttc ctttgcttcg cgaattgctc cttctaaact
    17461 gtcttcccca gaaacaatac atccagttgt cattccccac atatttggca atgttttttt
    17521 acttttagac cttttctgaa ttaaaatttg agagttacta tttaaaatcc acacttcaac
    17581 tgccaaatgg taataacctt cttcaataga attacctctt tttataacat ttcctgtttt
    17641 aattccatca gcattatata aatcccataa ttccatttca aaatctcctt gactttacta
    17701 taaattagat aaactacaaa tatattttag cataattaat tctgctcatt ttttattaca
    17761 atacttgatt tacatttatg ttcattgctt ttcttttcct tccattctct tatatcatct
    17821 ataataaatc tatgtttcag caattttgtg tcaaatttaa atattctaaa cactatttgt
    17881 aatacatatc ctaaacctaa agcacttaca agcgtaccaa tacctacaga acctcctaat
    17941 aaccatccaa caactaatgc tagtatttca agaattgttc taacaagacg tacagattta
    18001 ttagtttttt tctgaagagc aatcataagc ccatctctcg gtccacttcc taaacaaaca
    18061 cctaagtata gaaaacttgc tatagctgcc aaaataattc ctataacaac cataaacaca
    18121 cctatataag tgttgcttgc atgaggtatc actccagaaa atattactaa atcaataaaa
    18181 attcctataa atgtcatgtt gagtaaagta ccccatccta tattttcacc aaaaactgca
    18241 tccaatataa caattacaac tcctaccatt atagaagcct gacctatagt tatgcctagc
    18301 tttatagata aaccttggtg aagtacatcc caaggcataa gacctacatg tgcattaatc
    18361 ataagcacag aagaaattgc aaatataaaa aaacctgaaa ataatcttat catacttttt
    18421 aaacttattt ttcccatcaa aaatcactcc tcataataat aataacaata aataccaata
    18481 aaatatatat ataaatacga aattttacag aattatttat taggttaaga taaaatttta
    18541 attataaaaa gtggcaatcc aaattttata cattttcacc tatactctaa gctttcgtgt
    18601 ataaaaaacg gatataccac ttttttagta tataaacatt tttagttttt cttattaatt
    18661 ttcactataa attctagctt cttcttctcc atttagtact cttaaagttc caaaagcaag
    18721 tgattccaac tcattttctc ctgccataat ttctactggt gctataaact caactttctt
    18781 tttaaccatt gaagtaaaca tttcagaata tgcaattcca cctgttataa ttatagcatc
    18841 tacctttcca tctactacag ttgctaactc tccaatacct tttgctaact gataagccat
    18901 tgcttcataa ataatttttg cttcttcatt tccttctgct atcatttttt caacttctct
    18961 agcatctaca gtatttaggt atgaaactat accaccttta cctcttatct ttttagtcat
    19021 ttctctttct gaatattgac ctgaataaca ggcagccact aattttgtag caggtactct
    19081 tcctgacctt tctggagaaa atggtccttc atcatcagat agcatatcaa ccattcttcc
    19141 tttttcatga agataaatac ttactcctcc accaatgtga gctactatta agtttaagct
    19201 cttataatct tttcctttat ccttagcata ttttaaagcc attgctctag tatttaatgc
    19261 atgccctgca cttgatctat ccattccaca aagtccagat attctcgcta catctataag
    19321 ctcatctact gcaacagaat cataaatata tgagttgatt ccaagaggtt ctgatattgc
    19381 atgtgccaca acagcaccta aattggaagc gtgttcaagt actggtctat gtcttagtac
    19441 atcaatcatt tcttcattta ctaaatatgc tcctgatttt actggtggta aaactccacc
    19501 tcttcctact attgcactaa gagattttaa gtctatacta ttttctttaa gaatattcaa
    19561 aactgcttcc ttacgcattt caaactggtc ttgtatagta ttatattttg caatctcttc
    19621 agctggatgg tctatcgtct tcacaagaat ttgttcttct ccatcatata ctgctatttt
    19681 tgtagaagta gaacctggat ttatggctaa tattctgtaa gtcataattt tcttcctttc
    19741 accttaattt ctatagtcta tttatatcta ttataaacta tttgctaacc atttccatac
    19801 cttcatggaa agcttttatg tttaattcaa caaattttgg tttaacattt tcacttataa
    19861 ttttttccca atcaatagac tctaattgca tagatttaac tagacatcct aataaaataa
    19921 cattcattat ttttgaattt cctagttctt cagctttatc agctgcattt ataacttttg
    19981 catttaatct acttaactct gcatctatat cactttcttg atattcagct cctccgatta
    20041 aaacagtcat agaatctatc ctatgattat ttactaaagc ttttccttct ggttttaaat
    20101 aattgaacca tcttaaagct tccatttttt caaaagatac taatatatct gctccaccaa
    20161 tttctataac tggagaatga acacaatctc catatctaac ttgtgaggaa actgaacctc
    20221 ctctttgact cattccatgt atttcactca tctttacatc atatccagct tccatcaatc
    20281 ccatagttaa taatttacta gcaagtatag ttccttgacc tcctacacct accaaaagta
    20341 tactcttagt catattattt ttcctcctta actattgctt gttttggaca aacttgtgca
    20401 catactccac atcctacaca ctgatttcta tctatatttg ataacttatt ctctttatca
    20461 aatgatagag ctggacatcc agttttcaaa cataatttac atcctataca tttatcatgg
    20521 tcaactttac acttagtctt aaatggatta ttaaattctt ctatatcttc tttagagaat
    20581 tttttaagta cacatggcca tcttgttatt attactgatg gttcatcttc tatagctaaa
    20641 gcccaatcta gtgcttcatt tacttctttt aaattattag ggtttataac tcttacatgt
    20701 tctattccac aagctttaac taatccttct atatcaactt ctttagtttt agcaccttgt
    20761 aaagtatatc ctgaacctgg gttttcttgg tgacctgtca ttccagttat tctattatct
    20821 aatataaccg aaatagaatt acctctattg taaacaacat ctaaaagtcc atttattcct
    20881 gtatggaaga atgttgagtc tccaagtaca cctaccaatc ttttttcatt atcatccttc
    20941 atattaagaa ctttttgagc tccatgtgca gttccaaaag cagaacccat acaaacaaca
    21001 taatctattc cattatatgg aggagcaaat ccaagagtat aacaacctat atctccacca
    21061 actattaaat tttttctctt tccaagttca tagaagaatc ctctatgtgg acatcctgca
    21121 cagaaacttg gtggtcttgg tgttactaat tcagatttgt attctatagt atcatttgtt
    21181 tttccaaata tagcttttct taaaacatct ggtgtcattt ctccatatgg tggtattaca
    21241 tcttttccaa tacaatctat tccatatgct tttatttgtt cttctataaa tgggtcattt
    21301 tcttctataa catatatttt atcaactttt tctgcaaatt cttttatttt ttcataaggt
    21361 aatggatttg taaatcctag tttcatatat gatgcatttt ttccaaaaac ttctttggca
    21421 aaattacagc acataccaga ggctataaca cctatttttg tatcatttat ttcatagtag
    21481 tttaaatcag tttcatttga gaatttttta agaatttcca ttctttcttc aacaacgccc
    21541 cttcttattt gagcatttgc tggaacagtt accattttct tagcattttt aacatactct
    21601 ttaatttcaa cttcttctct atcatagcac tccactaatc cttttgaatg acaaagtctt
    21661 gttgtaactc tatataaaac tggtgtatcg tatttttcac taacttcaaa agcttctttt
    21721 atcatatctt tagcttcttg actagttgat ggctcaaata aaggtatctt tgcaaatttt
    21781 gcatacatcc tattgtcttg ctcattttga gatgaatgca ttcccggctc atctgctgta
    21841 ataagtacca taccaccatt tacccctgta tatgcataag taaatattgg atcagctgca
    21901 acattcaaac caacatgttt catagaagcc attgttcttg ctcctgcaat tgaaccccct
    21961 atagcagcct caagtgctac cttttcgttt ggagcccact ctgcaactat tgcatcttta
    22021 tatgttgcta tattttctaa tatttctgta cttggagtcc ctggatatgc agatgcatat
    22081 ttaacaccag cctcataggc tccacgtgca attgcttcat tacctgtcat caattgtttc
    22141 atataaaatt ccctccatct acaattatta aattcatagt ccacccaatt tgttcaatga
    22201 aattaattat ttatttttac ttctaaactt tcaagtgctt cttttataat acttggtgct
    22261 ttcttacatt tatcttcaga aactgcacaa actgcaaatc ttaaacccat ttttaatgga
    22321 actgcaaata aattatgttt agtcaattct tcacatactt cttttggatt atcacatggt
    22381 atacttacaa agaaacctgc tatatatgga agaatttcta atcctactct ttcagcttct
    22441 tttacaaata catctgctct tctagtaagc atgtttttgt atatttcttt ttcatcctca
    22501 tattctttga attttttagg gtcatttaca atgttagata atactgccat ggcacttcta
    22561 ttacaatttg accaatttgc tctacatgaa tgaacacatg agtaatggaa ctcttcagct
    22621 acatcttcac ttgaagatat acaaattata gcccccattc tcataccata agctgtaaat
    22681 ccttttgaca tactgaatcc aaccaatacg agaacgtttt caggcaaatt agaaaatttc
    22741 ttaaaaaact ttctacatac atcatcatca cctgcaaagt caatatatgc tgaatctacg
    22801 aaaaatatta tctttttgtc tttatctttt gcgacttctt ttgataagtc taatatttta
    22861 tcccactcat catctgcaac actatatcca gttggattat gcgctggtgt gtttataatt
    22921 gtaaagactc taccttgttt ttctgctata tttacaaatt tttctttaaa cgactcaaaa
    22981 ttaaaccttc tattttcatc aaaaagttgg taattaacta cttttctatt agcctcttca
    23041 gctatactta catatggact ccagaaccaa tcagatgtta atacctcatc tccttcatta
    23101 gtatagttcc atacagctaa ttttattgca ccacttcctc ctggtgaagc taatactctt
    23161 atatgtcctt ctggtaagta atctctgaaa aatacttttt taactgcttc taagtaatct
    23221 ggttgacctt caagagctgc atatgcacct atctcacagt tatctaatgc tttatattct
    23281 tcatatacag ttttcattgt tatcaatttt cctgaatcat ccattagagc gcctattgtt
    23341 gcatttatta cattatccat accaaaagcc ttctctgctg cttgagctct gccagatatg
    23401 ctaaatataa catcattttc ttttggccac attgcatgct taccaaccat actttgactc
    23461 ataccatcac ccctaaaatt gtatttactc ttacattata tattaagcaa ttactatgcc
    23521 aataaatccc actttatgta aaattgattt tgtttagaat tattattttt ttcattatta
    23581 aattaagtgt tttaactatt tttcttataa atatatatgc ctgtctaaaa aaataaaaat
    23641 ttgcaaaaaa gtaatgttaa tttttcttaa cacttgtttt aaaaaattaa cattacttca
    23701 aaataattta tatgtaatta tatttaaata tttttattgt atttcttcca taaagatgtc
    23761 ctgcttattc caagaacttg tgcaacttca tttttagaaa gtccttgagc aaaaagcata
    23821 cttattattt tttcttcaac atacttattt acttctttta tatctatact tatcttacca
    23881 tcatttatct tacttatatt tatagattca tcttggactt ctacacttgc tgtcgtttca
    23941 gaattaaatt tgtctacttc agagttagga agtaattttt tagttttaaa atctctatct
    24001 tgtctcaatt taattttacc tgtcacaaca tatttttgag ctattgtctt taactctctt
    24061 acatttccag gccagctata attatatagc ttatccattt catctttagt caaaacaaaa
    24121 ttttcatcta tactgtttat tccattgaga ccatcatcct ttaatacttc atttacaaaa
    24181 ttgttaaaca aaggtattat atcttctctt ctgtctctta aaggaggtat atttatctct
    24241 aaactactca atctataaaa taagtctgct ctaaatgtac ccataactat tttttcggtt
    24301 aaagattcgt tcgttgctgc tataatcctt atatccagag gtattatata atcagaacca
    24361 attctcatta tttgacgttc ctctattact cttaatagtt ttgtctgaat attaaaggat
    24421 agactattta tttcatctaa aaaaagagtc cctccatgag caagttcaaa tagccctctt
    24481 tttccaccct ttctagcacc agtaaatgca ccttcttcat agccaaaaag ttcactttca
    24541 agtaaatttt ctgctatagt agcacaattt atagcaacaa aaggcctatc ttttctttta
    24601 cttatattgt gtatactatg agctataatt tctttaccag acccactttc cccataaagt
    24661 aaagttgtat aatcactttt tccaattttt ttagcttctt caataaattc tttagttaat
    24721 ttatctttaa ataaaaaatc atcaaaagta tatctagcat agagaccttt ttgattcaag
    24781 tcaaatctta tttttctttc taagttttgt agcttggtta tatcttgtat tattcctaaa
    24841 actccataag tactattatc aacttttatc aatgttgtcc tagtattaac aattagatta
    24901 tttatatttc ttatctttct atcttctacg tcctcttttt catgtaaaca atctaacatc
    24961 cactccattt taggaaatac atctaagatg tatttattaa gtgcacattt tctctctact
    25021 ttaagcatgt tttttgcact ttcattgtac aaaattatac tgccattact atctatagca
    25081 attactccat cttttatacc atcaagtata tttcgtaaca cttcattatt aaacttttct
    25141 tcacctaatg tatctaataa ttttttacaa tattctacag cttctcttat agattcatca
    25201 ctagcagttg caaatacact atcaattcca tattgccttg caaaagaaca tgccaaacct
    25261 cctcctacga ttacaatttc atctttttgg tctatatatt ttacaacttt acttcttatc
    25321 tcatacttag attcaaacca ttcttcagtt atttcagtac ttatgacatt tctccagcca
    25381 acatagtcaa aagaaacttc attgtctcca agaatcaata ctactttttt agaatatttc
    25441 tttgctattt ctattgctct taaaaggtca gttgacttca tattcattgg tataacaggt
    25501 acatttactg tatctattac taaactataa cctccacctc taccaattat agcttgggca
    25561 cctttttcaa caagtatacg accttgattt tccattaagt ctaggttaag tatgtcgatt
    25621 attatagttc cattttctac atcttctcta tataattctt ctattctttc ttttaattca
    25681 atatcagagg ctataattcc tatttttttt cgcaacaaaa tcacctcaat tttaaattat
    25741 aatgtattga tttctacctg ctttttttga tttatatagg ttcttatctg catcttcaat
    25801 taatatttca acatcttttc tactacgaca tctttttata cttactccag cacttatagt
    25861 tatatagttt tttattttag aatatatatg ttcaataccc tcaaattcaa gaagtttgaa
    25921 aactctttta atatataatt ctatattatc aatctcttca acaccgattg attctataga
    25981 atctactaat attaaaattt cttctccccc atatctgatt atgtgttcgg taatatctat
    26041 aaatacactt cttataatat cagttacctt aactataact ttatctcctg ctagatgacc
    26101 ataattatca ttataacttt taaaacaatc tatatcgacc agtattgcga ccatattttt
    26161 gtctctggtt tcattaaata aatccaactg ctgttccaga tatcttctat tatatagttt
    26221 agtaagtcca tcttttaaaa tatcattttc taatttctta ttatcatcca ctagtaatct
    26281 taaactctct tgtttttgtc tgagttcata ttgtttgtga attgcttgag atgttttata
    26341 ggaattattt ttttcccacc tatcagaata ccaatccata cttttataat attctattgc
    26401 cagtttaaaa tcttttttta gctcatatcc atttgctatt agcccataaa atatagatat
    26461 ttttctaaga ttcaatgaac tctttttaac taaatttaaa ccttttatat aacaacttat
    26521 accttcatct atattaccaa attttatata taaatctcca tacaacttat atatgtaatc
    26581 tagtttagaa ttatatataa aaacatctcc aaaactttta tatatatttt ttgataaaat
    26641 taaataggtg tttacctttt caaaactaca attatctttc tttaactcaa tttcagctga
    26701 atataaaaat ataaatgaat ataaataatc cttatataca ccttcaacaa ctttcattaa
    26761 ttttatagtc tttaataaaa taacttctgc ttctttattc atatcttctt ttaaatatgc
    26821 ccatataagg tctattttta tagacactct ttcagttact gatattgagt tattactgtg
    26881 tgcaacatct aatacattat ttatgtattt tatagcttct acattatttc cactctctaa
    26941 ataacacaaa cttattatac atttacaaaa agcctctata gagtataaat tattttcttg
    27001 agccaatttt agacattcaa ttaagtattc catacttttt ataaagttat taaataaata
    27061 tagataaact ctcccaaata tataatttgc cctacttaca agagctttat tttttaaagt
    27121 tttaaaaaaa gacacttctt ctactaaagc tattacatcc gttttggtct gatataaagc
    27181 acttatttct acacataaac tcatatttaa caataccaac aactcattta aatgattttg
    27241 tcttataatt ttttttgctg agaaataaaa attatttacc ttatcatatt ttcttataga
    27301 aatagctgat aaagtaagat aaatataaat tttagatatt atatctgaat catcttttaa
    27361 tgacaatttt ttaatatact ttaatgactc tatcaaatag ttgtatgatg cttctctatc
    27421 tttttttata tagtttataa gactaattaa atataaagta tagactctac tattatcttc
    27481 taattttgta tttaaaaggt ctttgtgata atccaagatg tagtttaaat ctgtcaaatt
    27541 tagatagaat ttagtcaaca tatcgtattc tatcttgttt atatttctct ttaaatcttc
    27601 tattaaactc cttttcaagt aaatcaccaa tcctatttca acagttaaaa attcttaaaa
    27661 tcatgataat gcaaacatct atttctacca ctttcctttg ctttatataa agctttatca
    27721 gcattttcaa ttatttcttt tatatctata ctactatttt tacatgtatc aatgccaata
    27781 ctaactgtca aattattgtt taaaaatttc tttacaatcc tacataattt tcttccaaat
    27841 attttacttt ttttataatc tttacataca gataatatca gaaattcttc tccaccatac
    27901 cttatcataa gcatgtcttt ttttagatat ttttttatta ttatagttat atttttaaga
    27961 gcaatatctc cattatagtg tccataagta tcattgtatt ctttaaagta atctacatct
    28021 atcataaatg ctgtgcaata ttcactaact tcttgttttt ctaaaaaatc gttcaaaaaa
    28081 gttctattat atgcacttgt caaatggtca acatactttt ttttatctaa atcaagtttt
    28141 acttttctca tgttatttat ttctttttct atatactcat gtctataatt taaggaatct
    28201 atataatttc tatttcgagc ttttatatac atcattttta actcataata cattttaaag
    28261 tatttcatac tcatttcata attttgaatc ttttcaaaac acaaatatat actcttgtat
    28321 gctaacttca cataattata atttttagca tttttagatt tttcaaggag ttttttattt
    28381 gtgtttaagg cattatcata atatccaaag atataatata tctttgcctg gtgataaatt
    28441 atttctaaat catatattat atattcttct atatttttta tcatatttaa tatgttttta
    28501 gctctatcta aatagcatat tgattgttca aaagattttt cattactttt tgcataatac
    28561 atggctaaac ttataaataa atcaaacttc tctacttctt ttaagctatg atttttaatt
    28621 ttttctagat atacttcaga ttttgctaaa ttatttattg cgacaggata atttctagtc
    28681 tttattaata ttttagttat gttgtttgat gctctatatt tttgaattat atttacattt
    28741 ctatactttt tattgcttat tacttcattg aaatattcca tggaacattc ataattttca
    28801 aacgaacatt cacactcacc tatctttata ttacatagtg aagatacttg catatccttt
    28861 agtaaatctg catattttct tgcttttaaa aaatttacct tagcaattag agcatcatcc
    28921 aaaaacaaaa aatatatttt accaataata aaaaaatata tttttttaca attaaaatcg
    28981 ttaatttctt ttatctttat atacaacgtt tctatctctt taattattac agaagattct
    29041 atacacttac ttgccttaat gtaaataagt tgtgatttaa aaataatttc ttcaattaga
    29101 aaattatttt catcacaaat aagattaaat ttatccatat ataaatttgc cttatttaca
    29161 tcttcatttt ttaaacttaa aatagctatt tgtgaataaa atcgtgctaa aaatttataa
    29221 tctttgggta agcatttatc aatatattta caggaaatca aaatatactc tttcattttt
    29281 tcactaaacc cttgaatacc atataataaa gctagcaaaa aatttgattt taataacatt
    29341 aaactatttt gttcagtttt atagcaatca attaaattct ttactacatc aattttattt
    29401 tcaataaaat cgttattagt caataatctt tcattcaagg ttagtttaaa cattgaatct
    29461 aaaattgtat catctatctc ttccaaatat ttactatata ttgtaactca cctccgactt
    29521 acattatctc ataaatttag taattttcca tactattttt gaaaaaagtt gatgtctcaa
    29581 tttagaaatt tctcttaaat taagacatac tttacactaa actatacaat tttctatctg
    29641 aactatataa tcctgacaat tttcgcaaat tatcacactt acaatataac tattatcaac
    29701 tttatttgcc cttgatagtt tattaaaaga tagtccttta taatcaacag atatattgct
    29761 tattacatat tctccatctt tactgaaaat ataaaagtga tattctaaaa aaggaaagaa
    29821 ttttttcttt tcttttactc cttctaaaca taatggacat gcttcttgat aatattctac
    29881 atcaaaatca acttcttctg cttcattaag tatatcaatt atttttgaaa tacttactcc
    29941 ttgaactgga ttttcttcat catttattaa agcactacag ttctcctctt ttaataaata
    30001 ttccttatca tcatatataa acttatataa actcatatta tatcctcctt ataattatta
    30061 atctccaagt tattctacca tttaaataaa gttaataaaa gtaattgttt ataatcttta
    30121 taattaagtt atgtatacat atattcctat gcgctatctt aattaatgat tttaaaatcc
    30181 aagtttgcac tttgaacatc cagtttccca aaatctattg tcaaaactca ctttagttat
    30241 taatataatg atataaatat ataactgcat agatgttaca cacttaacta tttaatatga
    30301 tacgatttgg tatctaaatt tatatattgt atataggggg agatatatat gtataaagat
    30361 aaaagtgatg aatgtataca cttaatgact gcatacatcg atagtataag tggatattat
    30421 tcatttattg acacacaatt agaggatttt atgatgaaat atggtgaaaa cattgttgat
    30481 tcaaatttac acagtataat gatgttgctt tgtaaatggg gattatctta gcatttcaag
    30541 aaactttttt gtatattgta ttctatatta tttattcatt aacaaaaaag attgacataa
    30601 acttaaaagc tatatataga tttctttaaa aatctatata tagctttttt aattttttca
    30661 aaatgtatac ttaaataagt tagttttttt caaaatttga ctatctaata tgatataatt
    30721 taactatcta caacaataaa aaatatctaa tatgtattat ctagtttagc tcatcataat
    30781 aacatcccta tatttacaat taagatattt tcaatatagt aatactcaat tttaatatta
    30841 taaaaaggag agattttgta tggattacaa tgacttacta aaatcagcta gagagaactt
    30901 taatggaaca tgtaaagtat gtaaaatttg taatggatta gcttgtgctg gagatgttcc
    30961 tggtatgggt ggtaaaggaa gtggttcgtc tttcattgaa aatagaaaaa gtctagaaaa
    31021 aataaagata aatatgagag tcatacataa tgtttcaaag ccagatacat ccatagaatt
    31081 atttggtaga aaaatgagtt ctcctatatt cgctgcacct gtatcaggta ctatattgaa
    31141 catgggtggt aaagtttccg aaaaagaata catagagcct gttgttagag gttgttctaa
    31201 ttctggaatt tatgctatgg ttggcgatac taatgtagat acttttttac tggataattt
    31261 agatgtattg aaggataata ggggaaatgg aattgtattt ataaagcctt ggaataattc
    31321 aaagataata gataaaatta gattgtctga agaagcaggt gcttttgcag ttggtgtaga
    31381 ccttgatgct tgtggactta ttaataatca atttcaagaa aatccttttt ctcctaaaac
    31441 aattgatgag attagagaat tggttgaatc cactagatta ccttttatta taaaaggaat
    31501 tatgactgta gatgatgctt tgatggctgt agagtctggt gctagtgcca ttattgtttc
    31561 aaatcatggt ggaagagtac ttgattatac tcctggtact tgtgaggtac ttccagatat
    31621 agctaagtct gtaaagggaa agataacaat acttgttgat ggtggagtta ggactggtgt
    31681 tgatgtagtt aagatgcttg gattgggtgc tgatgctgtt ttgatgggaa gaccttttgt
    31741 tactgcttct tttggcggtg gtcttgatgg tgtggagttt tttatagaga aggttaggaa
    31801 tgagttatgt gagactatga ttttgactgg ttgtcaaaat gttaaggata tagatggtag
    31861 agttatatgg aatttattgt aaaatagttt tataacattt atatttaaat agtgtctcat
    31921 ttaaattgaa aaatcatatt gagacactat ttaatatatt tttagatttt aatcctatga
    31981 aagagtaggg tcagttagtc tacccaattt atcccaagta gctggaccaa ttattccatc
    32041 tgcagacaaa ccgtattttt tttggaaact tacaactgca ttatatgtct tacttccaaa
    32101 agaactatct atacctacat tataaccaag taaagttaac atgatttgtg cagcttttac
    32161 ttcttttccg ctattaccct ttcgtataac ttttgttgta cttatagtca aatactcatt
    32221 actcataatt gttatagttt tagcacctat attataagaa acagtataac ttgcataaac
    32281 acctttacta ttgtcctcat tcattagatt agctgattct ggaacaaata tctcatcatc
    32341 tggcttaggg tctatattta tctcttcaca attttgttta tgttcatctc ttatttcttg
    32401 tggcgcattt tcatatgtat atatataccc agaaagagta aaagaatcta ggtttttctc
    32461 tggaacagtc tctttacttc ctcctttctc tttacttgtg tcagcaaatg ccacacttgt
    32521 aaaagtaagc aataagcaac acataatagc tactattttt cttaattttg ttaacataaa
    32581 atcctcctta taattatttt attaattgat tataatcttt catatccatt tctattatgt
    32641 catagtctct aggtatttta ccttctaatt cgcatttatc ttcataaaat ttcctaattt
    32701 catttggtgc atctttataa taaatattta taattttatc agtcgtctta ttcaataaaa
    32761 attcattaat attgttattc attccattat taccctcatc aattctaact tgagcatcaa
    32821 cttcaacaaa agatgttata gaagtcataa atactaaaac agcaattagt attccacttt
    32881 tgcctttctt tttaacaata ctctcaagtc tcttttccaa atttgtctta tcaaactcgg
    32941 ttgtcaaaat cttactatta taatttttac taaacttaat tgactttata agtgctagtg
    33001 catattcttt tttatctttt aaagaacatt ctaccaaaac actttcatca caacataatt
    33061 cacaatctag atttacttta ttgctcatta catatacaag tggattaaac caatatatta
    33121 ttctaacaga caaaactaaa aactttatta aaatatcttt atttttaaaa tgcattaatt
    33181 catgtttcaa aatccaagtt agttcatctt tactataagg atagtctggt aagaatatgt
    33241 aagatttaaa taatcccata cctgctggac ttatcaattc atcagaacct cttaattcaa
    33301 ttttcttttt tatatttaat tcttttaaca agtttttgta gatacagttt atatcattat
    33361 cttcaatatc ataagataca tcaacaacta gatttttaaa tcttgtatac tttataaatg
    33421 tataaactgc aatgactata gttacaaata accataaata agctacatac agcataagat
    33481 tattatctgt agaaatatca atttgtgtaa tattatttcc taatgcattt tctttgggtt
    33541 cttttacttc atacactatt gtataattaa atagaaaaag taacattcta aagactatta
    33601 tcaaccaaat ataataattg aatctcttac taaacttctt aaataaatat cttttcaaaa
    33661 ataataatag acaaatacca agactacata caatagttgt ctttataaga ttttcaaaaa
    33721 catatagcat ataattattc atcctttaaa ttatcaaaat aactttctag aaaatctagc
    33781 ttatctttac ctatattttc atcatcatgt aatgctgaaa ttaagcttct taaagagtca
    33841 tcatgtatat tacttaggaa atcctttgtc tcaaaactta aataatcttt gtgttttact
    33901 cttattgtgt aatgtgtata tctgtctatt ttttgagcat ctaagaatcc tctttttacc
    33961 agcctagata aaagtgtcag tgtggtggtt tgtttccagc catatttttg ttccatagct
    34021 tcaataacat cttttgatgt cactgtaaca tctactttcc aaatgaattt cattactttt
    34081 agttctgctt gtggtatttt tcttatcatt atttacacct ccctcaaaac tcctgctacc
    34141 ttaattctac aacatgtgaa ttttttagtc aaacacttta tgaaaaaaat gtgaattttt
    34201 gtactttttg ttaaatttct aattttttta caatattaaa agttagattt taaaatatat
    34261 ctatttaaat attttacttt ttacatattt aattacaata gtgtagaatg ttatttacac
    34321 attaaaacta tttaataaaa attcctatat tttcacacaa ggaatattat aatacttttt
    34381 tttaaaataa actagagtaa tatctaataa attttaataa ccttctaatt atgcctttat
    34441 gatattaaaa catctatttt atactgatta tttac
//
LOCUS       DAGQVA010000046        33345 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.046, whole genome shotgun sequence.
ACCESSION   DAGQVA010000046 DAGQVA010000000
VERSION     DAGQVA010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33345
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.046"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            230..547
                     /gene="flgB"
                     /locus_tag="MIV85_002301"
     CDS             230..547
                     /gene="flgB"
                     /locus_tag="MIV85_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBY2961633.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            555..959
                     /gene="flgC"
                     /locus_tag="MIV85_002302"
     CDS             555..959
                     /gene="flgC"
                     /locus_tag="MIV85_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBY2961634.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            969..1286
                     /gene="fliE"
                     /locus_tag="MIV85_002303"
     CDS             969..1286
                     /gene="fliE"
                     /locus_tag="MIV85_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBY2961635.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1311..2861
                     /gene="fliF"
                     /locus_tag="MIV85_002304"
     CDS             1311..2861
                     /gene="fliF"
                     /locus_tag="MIV85_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBY2961636.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            2874..3944
                     /gene="fliG"
                     /locus_tag="MIV85_002305"
     CDS             2874..3944
                     /gene="fliG"
                     /locus_tag="MIV85_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBY2961637.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            3937..4668
                     /locus_tag="MIV85_002306"
     CDS             3937..4668
                     /locus_tag="MIV85_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBY2961638.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            4672..5991
                     /gene="fliI"
                     /locus_tag="MIV85_002307"
     CDS             4672..5991
                     /gene="fliI"
                     /locus_tag="MIV85_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBY2961639.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            6022..6468
                     /gene="fliJ"
                     /locus_tag="MIV85_002308"
     CDS             6022..6468
                     /gene="fliJ"
                     /locus_tag="MIV85_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBY2961640.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            6497..7702
                     /locus_tag="MIV85_002309"
     CDS             6497..7702
                     /locus_tag="MIV85_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBY2961641.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            7720..8328
                     /locus_tag="MIV85_002310"
     CDS             7720..8328
                     /locus_tag="MIV85_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBY2961642.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            8355..9338
                     /locus_tag="MIV85_002311"
     CDS             8355..9338
                     /locus_tag="MIV85_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBY2961643.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9351..9554
                     /locus_tag="MIV85_002312"
     CDS             9351..9554
                     /locus_tag="MIV85_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBY2961644.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9554..10372
                     /locus_tag="MIV85_002313"
     CDS             9554..10372
                     /locus_tag="MIV85_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBY2961645.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10362..11057
                     /locus_tag="MIV85_002314"
     CDS             10362..11057
                     /locus_tag="MIV85_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBY2961646.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            11069..11512
                     /locus_tag="MIV85_002315"
     CDS             11069..11512
                     /locus_tag="MIV85_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBY2961647.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIADLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11527..11901
                     /locus_tag="MIV85_002316"
     CDS             11527..11901
                     /locus_tag="MIV85_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBY2961648.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            11902..12567
                     /gene="fliP"
                     /locus_tag="MIV85_002317"
     CDS             11902..12567
                     /gene="fliP"
                     /locus_tag="MIV85_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBY2961649.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12580..12849
                     /gene="fliQ"
                     /locus_tag="MIV85_002318"
     CDS             12580..12849
                     /gene="fliQ"
                     /locus_tag="MIV85_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBY2961650.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            12861..14675
                     /locus_tag="MIV85_002319"
     CDS             12861..14675
                     /locus_tag="MIV85_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBY2961651.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            14684..16759
                     /gene="flhA"
                     /locus_tag="MIV85_002320"
     CDS             14684..16759
                     /gene="flhA"
                     /locus_tag="MIV85_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBY2961652.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            16734..17750
                     /gene="flhF"
                     /locus_tag="MIV85_002321"
     CDS             16734..17750
                     /gene="flhF"
                     /locus_tag="MIV85_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBY2961653.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            17747..18625
                     /locus_tag="MIV85_002322"
     CDS             17747..18625
                     /locus_tag="MIV85_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBY2961654.1"
                     /translation="MIDQAQILRKIAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            18639..19340
                     /locus_tag="MIV85_002323"
     CDS             18639..19340
                     /locus_tag="MIV85_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBY2961655.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19356..19778
                     /locus_tag="MIV85_002324"
     CDS             19356..19778
                     /locus_tag="MIV85_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBY2961656.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            19763..19948
                     /locus_tag="MIV85_002325"
     CDS             19763..19948
                     /locus_tag="MIV85_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBY2961657.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            19989..20762
                     /gene="flgG"
                     /locus_tag="MIV85_002326"
     CDS             19989..20762
                     /gene="flgG"
                     /locus_tag="MIV85_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBY2961658.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            20783..21544
                     /gene="flgG"
                     /locus_tag="MIV85_002327"
     CDS             20783..21544
                     /gene="flgG"
                     /locus_tag="MIV85_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBY2961659.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21567..22448
                     /locus_tag="MIV85_002328"
     CDS             21567..22448
                     /locus_tag="MIV85_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBY2961660.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22451..22825
                     /locus_tag="MIV85_002329"
     CDS             22451..22825
                     /locus_tag="MIV85_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBY2961661.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            22857..24260
                     /locus_tag="MIV85_002330"
     CDS             22857..24260
                     /locus_tag="MIV85_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBY2961662.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLYMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            24376..26313
                     /gene="htpG"
                     /locus_tag="MIV85_002331"
     CDS             24376..26313
                     /gene="htpG"
                     /locus_tag="MIV85_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBY2961663.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            26700..27830
                     /locus_tag="MIV85_002332"
     CDS             26700..27830
                     /locus_tag="MIV85_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBY2961664.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            28057..29079
                     /gene="splB"
                     /locus_tag="MIV85_002333"
     CDS             28057..29079
                     /gene="splB"
                     /locus_tag="MIV85_002333"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBY2961665.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            29261..30172
                     /locus_tag="MIV85_002334"
     CDS             29261..30172
                     /locus_tag="MIV85_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2961666.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            30187..30603
                     /locus_tag="MIV85_002335"
     CDS             30187..30603
                     /locus_tag="MIV85_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBY2961667.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(30703..31095)
                     /locus_tag="MIV85_002336"
     CDS             complement(30703..31095)
                     /locus_tag="MIV85_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961668.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            31236..31631
                     /locus_tag="MIV85_002337"
     CDS             31236..31631
                     /locus_tag="MIV85_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBY2961669.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            32034..32240
                     /locus_tag="MIV85_002338"
     CDS             32034..32240
                     /locus_tag="MIV85_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961670.1"
                     /translation="MSKYSSLWEYFKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(32397..33128)
                     /locus_tag="MIV85_002339"
     CDS             complement(32397..33128)
                     /locus_tag="MIV85_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961671.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
BASE COUNT        13596 a         3545 c         6019 g        10185 t
ORIGIN      
        1 agcaactttt cgaagaaata tttaaataca tattaaaatt tttttatatt ttcatgggac
       61 ttcattaaaa aaatattagt tttcttacta aattgataca ttattgtatt aatgtaatgg
      121 aaatgcgatt aatttaaata aataaagaag tcattttttg taatatagca acttcatttt
      181 ttttattaat aaacaaaata gataaaatat attttgagga ggggtgagtg tgaatacata
      241 tgacattata aaaatgggat tagatgcaac taatctaaga agtcagacaa tagcaaataa
      301 tatagcaaat ataaatactg aaggatataa aagacattat ataacttttg aagaaacact
      361 aaatgatgct atgcctaaaa tagaagaaaa aacagacaat tctaaaggtt taagagtaga
      421 tggtaataat gtagacatag aagaagaaaa agtaaatcaa gcaatggcaa cattacaata
      481 taatgctttg ataagttttg caaatggaaa aatagcaatg accaaatcaa taataagtgg
      541 gaggtaatta gaagatgagt gtgttcagtg gaatgagaat atctgctagt ggattaacag
      601 cagaaagttt gaaaatggat atcatatcat ccaatgtagc taatataaat gctacaagag
      661 gtccaaatgg agaagcatat aggagaaaag ttgtttcatt tgaagaaaac tatgataata
      721 aattaggtat gctaggagta aaagttacat ctgttgaaga tgataaatca cctcttaaag
      781 aagtatatga cccatctcat ccagatgcaa agccaaatgg atatgtagaa tatccaaatg
      841 taaatatatt ggtagaaatg acagatttaa taacagcttc acgagcatat gattctaacg
      901 tagatacatt gaatgctcag aagtctatga tatcaaaagc tttggaaata ggaaagtagg
      961 gataaattat gccaattaca caaattaaca atttaatgca aggtgcaaag ttagataatt
     1021 tgattggaga agcaaagcca ttaactctta ataataaaga agaaaaaaag aattttgaag
     1081 atgtaataat agatactata gataaagtta attttcaaca agtaacagca gatgatatga
     1141 aagaaaaatt tataaaaggc gaagatgttt ctatgcatga agttatgtta ataggtcaag
     1201 aagcacaact atctatgcaa tatttaatag aagttagaaa taagattcat gatgcatatc
     1261 aagaaatgaa taaggtgcaa atttagcctt ttgaacagga gtaataatca atgataacca
     1321 gttttaaaaa taagattaag gagcaagttg ctaaatctag gacaaagata agttctttaa
     1381 aaaagggaac taaaatagca ttaggtatag gggttattgc tatatgttta gcgctagtat
     1441 ttacagcaat atctgcgagc aaaaataagt atgcagtctt attttcagaa ctagatgctc
     1501 aagatgctgc agatatatca gcagagctag agtctaaaaa gatagatact aaggtaaaag
     1561 gaagtacgat ttatgtacct agaacagaag ttgataagtt aaggctggag ttagcgccaa
     1621 gtcttacagg tggttctaaa ggatttgcac taatggatga tagttcatca atagggctta
     1681 ctgatgaaga atttcagatt aagaaacaaa gaatgataca aggtgaaata gaaaaaacaa
     1741 taaagagttt tccacaagtg gaagacacta gagtacatat aacatttgga gagtcatcag
     1801 tatttgagaa ggaggctgtt ccagggagtg cagcagttta tttgatgcta aaaccaggga
     1861 cgactttaga aaaaaaccaa ataaagtctg ttatggcact tatatcagga agcgttacaa
     1921 atataccaga gaaaaatgtt caggttattg ataacaaaat gaatttatta tctgaaggta
     1981 ttttggagga tgaaaatgtt gatgaaaata atcaaccaat aaatagtggc attagtgttg
     2041 ataaaaataa ggcatctgaa caagcattga ataaacaact agaaaagtct attttagaaa
     2101 tgctagaacc gatatttggt aagggaaagg tgaaagctac agtaaatgct gatttaagtt
     2161 ttgatacagc tgaaaaaact gagataaaaa ttgaccctga taaagttgca ataaaggaga
     2221 caaggtcgaa aaattcatct aaatctgctg caaataatgt tcaaggtgta gatgctaaca
     2281 tgaataacca aggaaataac aatggtacta atacagaaga tagtttagat gagagttttg
     2341 agtatgaaac aggtaagatt gaaactcaca ctatagttgc gcctggagaa cttaatagat
     2401 tgacagcttc tgttgcaata gatggaaaaa tagctaaagg tgttcaagct gatgtagagg
     2461 atattgttaa taatgctata ggtatggatg gagcgagggg agatactctt agcgttgttt
     2521 caatggtatt tgacccagaa ggtaagaaag aggctaaaca agagctggaa gagattaaaa
     2581 aagaaggatt taaaaagaac ataataaaag cagttattgg agtagtagca gtaatagcag
     2641 ttggagctat tggatactta atatataaga aaagaagtga acgagaagat atggattatg
     2701 aagatgaaga ttatatttct aaatctgatt ctgttgatag gaaggataat cctctattag
     2761 gagatgatcc agaactgaca ttagaggaag ctgttaaaat gtatgcagaa gaaaagccag
     2821 accaagtaac agagataata aagacttggt taaatgagta agggggatag aaagtgtcca
     2881 cggaaattac aaatgttaat gcgtttgact taagtgatat aaatgaaagt gataagaatg
     2941 agaaggtaga aggtgagggt ttaaaaaaag ctgctgtatt attaatgaca ttaggcccaa
     3001 atgtgtctag tgatataata aaaagcttgc ctgataaaca agttcaaaaa ataggtttgg
     3061 aaattgcaaa tatttcttca atagcttcaa aagaaagaag agaaatctta aaagagtttg
     3121 tagaaataaa tagggcaaaa gattatgtta tagaaggtgg gcttgaatat gcaagagagt
     3181 tattaagtaa tgctttagga aatgttaaag caaacaaatt acttgaaggt atatcaataa
     3241 atacaagtac aaagcctttt aaacatatta taaaactaga tgtaaagaag atattagaaa
     3301 tacttaggaa tgaaagtgca caaactatag ccgttttact tgcacatatg gaaccagaaa
     3361 atggagcaga agttttatca tacttagatt ttgatttaca aaatgaagta gctatgagaa
     3421 taagctcaat gggttcaata tctccagaag taataaaggt aattgaaagt tcattagaag
     3481 ataaattaca ttcaataagt ggtgatgatt ttaatgatta tggaggggtg tctaccttag
     3541 ttcaaatatt gattaattct gatagaaaaa cagaaaagaa tattttggga actattgaag
     3601 aacaaaaccc ggatttagca gctcaaatta aatctcatat atttgtcttt gaagatattg
     3661 tcaagttaga tgatataagc atacaaaaag tgttaaaaga agtgactatg aaagatttag
     3721 tatatgcctt aaaaggtgta gatgatgaga tttcagatgc tatatataga aatcaatctt
     3781 ctagagcagc agatgcactt aaagaagaaa tggaaatggt tggtgttata aaggttacac
     3841 aagttgaggc ttctcaacaa aagatagcta atatcgtaag aaaacttgaa agagaaggtg
     3901 ccataactat tgtaaggaat tttggtggtg actttgttga ataataagat tattaaaagt
     3961 aaaaaagcat tatataaagg agtgctagat ttaaccataa tagataaagt tagagtggga
     4021 gaatcaaatg taaataaaga aaatgattgt agatttaggg atgaggtaat aaaagaagct
     4081 atagaatctg ctgagataaa aaagaatgag atattagaag aagcaaaaat aaatgcacaa
     4141 aatatagaaa agcaagcata tgaaaaaggg tatagtcaag gtcaaaaaaa tggatatgag
     4201 gatggatata aagagtcata tgatgaatat acccaaaaag ctaaagatga agcagatttt
     4261 ataaaaaatc aggcaaattt aatcttatta caagctaatg agaagatgac tgagtacata
     4321 aaagaaaaaa ataaagagat tgtaagactt gctattaata tggccagttc tgttttaaaa
     4381 aagcatttcg aagatgaaga atctatgagt gatctgttaa agcaaattat tcaagattat
     4441 gaaggaagta gttcatttat agtaagatgt aattctttct ataaagataa tatagagaaa
     4501 gagtttgaat tattcaaaga ggaaacatca ctaaaatcaa gtgtatttgt tattgcagat
     4561 gatagtatag ataaaggcaa tgctattatc caaaaggaaa atggaagaat aatagttggt
     4621 attgattgtg ctatggaaaa actaaaagaa gaattgcttg gtgaataaag tatgtataaa
     4681 actgatatat ctatagattt tgacaaaata aataagaaaa tagaaaattt agaactcact
     4741 atatcagaag gtagagtaaa gaagataata ggacttactg tagaagttga aggaataaaa
     4801 gcttttgttg gggagttatg cgttatatac aaccaagtta ataaaccagt gaattgtgaa
     4861 gtagtaggtt ttaaagataa agaagtcata ttaatggcgt tgggagaatt aacattgata
     4921 gcacctggtt gtaaagttat ttctaagggg atacctttaa gtgttatgtg tagtgataat
     4981 ttactaggta aagtacttga tggtcttgga aatcctatag acaactcaga tgctgtttta
     5041 ggagatagat acaacctgaa caatgaacct cctgatccaa tgaagagaaa aaagatacga
     5101 aatataatgg aaacaggtgt aagagcaata gatgcattta ctacttgtgg tgaaggacag
     5161 agaatcggca tatttgcagg aagtggagta ggtaagagta cgactctagg tatgattgct
     5221 aggaatgcaa aagcagatgt aaatgtaatt gctcttattg gagaaagagg aagagaagta
     5281 ctagatttta ttgataaaga tttaggtgaa gagggaatga aaaaatctgt tgttgtgtgt
     5341 gcaacatcag ataaagcccc tctagttagg ttaaaaggtg ctcttactgc tactgcaata
     5401 gcagaatatt ttagagacca aggcaaaaaa gtaatactta tgatggattc agtaactaga
     5461 tttgctatgg cacaaagaga agttggtgta gcaataggag agccaccagc tcaaaaagga
     5521 tatacaccat ctgtatttgc aatgttgcca aaacttatgg agagaacagg gacatcagat
     5581 aaaggttcta taactgcatt ttatacagta ttagttgatg gagatgactt taatgagcca
     5641 atagcagata caacaagagg gatacttgat ggtcatatag ttttatctag agacttggca
     5701 aataagaatc actatccttc tatagatgta ttaaacagtt taagtaggct tatgaatgaa
     5761 attgcttcaa aagaagacat aaaaatagcg tcttttgcaa gagacatgct tgctgagtat
     5821 agagaagcag aagatttgat aaatataggt gcatatgctt caggtacaaa taaaaaaata
     5881 gatgaagcaa tctattatca tgagcatatt attaattttt taaaacaagg gataaatgaa
     5941 aagagttctt ttaatgaaac tataagtagt ttgagaagag tttttgaata aacaattaaa
     6001 aaaatatttg aataggttgt gatggaattg gataaaaact ttaagtttag attacagaaa
     6061 gttttagact taaaagtgaa agatgaagaa gagataaaaa tggaatttgc taagattcaa
     6121 caaaaaaaaa tagatataga gactaattta gaaaacttag aaagtaatta tagcaaatat
     6181 tctataagta aaaataacga tagtattcaa aatcaaaaaa taactattaa ctatttacta
     6241 gctttaaaca attctataat ggatttatca gaagagttgg ataagtcaac aaatgaactt
     6301 gaaaaagcta gaaagcagct tataagcaaa cagatagaga gaaaatcatt agaaaaatta
     6361 aaagaaaaaa agtatggaca gtattataaa gaagaaaatt taaaagaaca aaacactaat
     6421 gatgagtttg caagtatgag ttatttaagg aatagacaag ttctataaga atagtaggaa
     6481 gtgaggatat tattgtatga agatacaagc agattcttat aatattatta aagatattgg
     6541 ggatagaaaa agttcatcta agaacaaaaa tataaaaaat aataaatttg aagataatct
     6601 atataaggca acagaccata aaaaagttaa agatagaagg gaagtaagta agcaaaatat
     6661 tagctcagat aaaccggaaa atagtgataa tgagtgtcat ttagatgaag ataaaagtaa
     6721 tcacttagaa gatgaaaata catatgaaaa agattgtagt aagaataatg aagctttgca
     6781 gcaattactg aatcttttaa aggataatta taaaaaagat aaagatataa acactatatt
     6841 gaataatata gaaaaactaa gtatatcaga tgaattaaaa caagaactta agcttaataa
     6901 aaatatatta aataagattg caaatcaaaa ttcagagcta aataaagcta atataaataa
     6961 ctctaatgat atagaaaatt tagacatagt taaattaaga gaacttttgg aagataatgc
     7021 taataaagat attgaagtaa ttactaaaac tacagaaaat gataccaaaa atatagattt
     7081 gtatagtttt gatagcaata gaatggataa tcttaactca aataaacaga aagatgatag
     7141 ctctgatatt ttggaaaaac tagcaggggt aaatggaaat aagagtggga attttggaca
     7201 agtaataaat aaaaatgttg atatgaataa aattaaaaat gataatgtca atttaaaaca
     7261 gatagaatca aatgtaatgg atgactctat aaaagctatt aagcatatga aaacaaatga
     7321 tatacaagaa ttgacaatta aattaagacc aaaagaatta ggagatatga atatacaatt
     7381 gttaaaagat ggtgaaagta tgagagctgt tgtgactgtt ttcaataaag atgtctttga
     7441 ctctataaat aaaaacatag cagatttaaa gcaacatctt gaacttacta atgtaaatat
     7501 aaaagatgta tcagtgcaaa tgcacagcga taatacaaat acatctgata cctttgataa
     7561 agcatttgaa caacagaata gacaaaataa ccaagaaaac atgagtaaga agaatacaaa
     7621 tgataagcat aataatgtag tcatagaaga tgacattaaa gaaaatacta ttgatgatga
     7681 tagagtagat ttactagctt agtaaggggg aagtattgca tgtacggaat agcaacggct
     7741 ttggcaggaa ctcagggaaa ctataggtca aataacttaa gccaacttga aagaaatatt
     7801 aatgatattg ccaataaaca agttagaagc aaaggaaatc agacagtaac agacaatggg
     7861 actccaatta taggacaagg tgatgatgct gataaagact tgtttatgaa gatacttgtg
     7921 gcacagatgg gtaatcaaga cccaatgaat ccgcaagacc caacagaata tgtgtcacaa
     7981 ttagcacagt ttgcaacttt agaaaagatg tcagctatga atgagaagct agatgtactt
     8041 ttagccttaa gtaattccac tctaataaac tctgctttaa gtatggcaac atcattaatt
     8101 ggtaaagaag tagaagtatc tggggaagag aaagaagatg aaaacattgt aggagtagta
     8161 aagtccacat atataaaaga tggggaagta cacttagaat tagaagtaga tggaagtgac
     8221 aaaactgtag gtgttaaata tgaaaaatta cttaaaatag gagaggtaga tgaaaattca
     8281 ggagaagaaa atgattcttc agaacacgaa tctccagaag aagcataata ttaaatgaga
     8341 aaagaggtaa attcatgata aaagcaatgt attcaggtgt aagtggaatg aaagcaaatc
     8401 aaacaaaatt agatgtaata ggtaacaatg tagccaacgc tggaactact tcttttaaga
     8461 aaagttcagc tagaataaca gattcatttt atcaaactgt actatatgca agtgctccaa
     8521 cagctgcatt aggaggaaca aacttaggac aagtaggtgt aggtagtaag atatcaagta
     8581 taaataaaga tatggtacaa ggaaatgtac aaccaactaa tagaccatct gatttaatga
     8641 tagatggaga tggatatctt ccagtagtaa gacaaggaac agttatgtat acgagagatg
     8701 gttcttttaa tttagataca ggatttaaag cagctgatgg tgctttgaag aatattaaag
     8761 gtggaagact tgtaaatggt gatggatata tgttacaagg tatgatttat gatggggaat
     8821 ataaagctga tactggagaa tttgttaaaa agggtgatgc taaaggaaaa gagcctattg
     8881 taataccact tcaaagtata agtcctaagg atggaacagt tcaaaatgta ctagagtata
     8941 atatatcaaa ggatggaaca gtagaatttt tattgagtga tggtcaaaga actcaatttg
     9001 tctatgatat acctgatggt gctaaggtag gagatacacc tgctggaata gataaattaa
     9061 aaggtacaat acaaaaagtg caaacatatg cattccaaaa tccagcagga ctagatgcag
     9121 aaggaggaaa cttgtttaaa ccatcagcaa actcaggaga cccacaaata gcaggagcta
     9181 caggcacaat aatacaaggg gcaatagaag cttccaatgt agatatagca gaagaattta
     9241 cagaaatgat aatagcaagt aggtctttcc aagcaaacag taaaataata tcgacatcag
     9301 acgagatact tcaagaaata ataaatctta agagatagta ggtacatatt atgataagag
     9361 taacggattt aaacggaaga aaatacatat taaattcaga ccttatagtg aggattgatt
     9421 ctgtaccaga aagtaggatt ctccttacaa caggagaaaa aaaccttgta aaagagtcgg
     9481 tagatgagat agtagataaa gtaataaagt ataaaagaaa aataaatgta ggttatatta
     9541 ggagcgaaaa ataatgaaaa aaacagattc actgacattt attggactaa tagtatctac
     9601 agtattagtt ttagttggtg ccgcaaaagg aagtagttca gggttaaaga atttttttga
     9661 tgtttcatca atattaatca cagtgcttgg ttcatttgga gctctaatga ttacatttac
     9721 tatagatgat ataaaactta taaaaaatgc attacaatac tcatttaaga caatgagtgt
     9781 atcaaagtta gatttactag aacaatttaa aacactttct aaaaaagcta gaaaagaagg
     9841 tcttttatca atagagagtg atgtaatggg aatagaagat ccatttatga agaaagggtt
     9901 agagctgtgt attgatggat tggaaatcaa tgagataagg tccatcttag aactagagat
     9961 agattctgtt gaagatacaa ataacagata ctctaaacta tttaaaactt ggggaacctt
    10021 tgcacctgct tttgggatgt tgggaacact aataggttta atacaaatgt tagctgacct
    10081 tacatctcca gatttaatag catctggcat gggaaaggca ttaattacaa cgttttatgg
    10141 ttctttactt gccaatatcg ctttgaaccc aattgcatat aatatagatg agaagactga
    10201 aaaagaaatt tatgtaaagg aaatgatgtt ggaaggtata ataagcatac aatctgggga
    10261 gagcagtata gtagttgagg aacgtttagc cacatacctt tcaaacaatg agaagttaga
    10321 aattatgaaa tccaataaaa atacagaaag agcaatgagc aatggcgcgt aaaaaaaata
    10381 agaaaaagga tgagataaat ccagatgcat ggctggctac ttatgcagat actataacac
    10441 tgattcttac atttttcgta ttattgtatg caacatcagt tgtagatatg gaaaaattta
    10501 aaaacatagc agatgcgtta aaaggtcagt tttctgggac aagtatattt agtacgggtt
    10561 caagtacaag tgagaaatct ccaatagaca gtgttttagt ggataaaaat gataaatcaa
    10621 atttagaaca ggatttaaaa gataaagtta ataattctaa cttacaaaat agtgtaacag
    10681 tcaaagatga tagtagaggg attttactag agttagatga ttcaatttta tttgactctg
    10741 ggatttctga gttaaaagta gatagtaaag ctactcttaa taaagtatat gacatgataa
    10801 agatgatgaa aaataagata gttatagaag gccatactga taatgtacct gtaaaatcaa
    10861 gtacacatga atccaattgg gatttatctt ctagtagagc agtaagtgtt gtaagatact
    10921 ttgtagaaga aaagggcatg gaccctagac tattttcggc aacaggatgt ggagagtatc
    10981 aacctttggt ttcaaatgaa acagcaaagg gaagggctga gaatagaaga gttaatatac
    11041 ttataactat tgactaggag gaagaggttt gttcaaaaat aaaaaaatta ttataattat
    11101 tttgatactg attattttct cagcgggagc aggttttttt atattaggag aaggtggaaa
    11161 taaacaagtt gacaagattg cagatttgtt tattccaaca ggaaaaggta aagatgaagt
    11221 aaagaccgaa aatcttgact tagaagagat ggtattaaag ctagctgatg aaggtgtaag
    11281 atatttaaaa gtatcaataa ctgtatctta tgattcttca tataaagata tagaaaaaaa
    11341 tacgccttta attagggata atattataaa ttgttttatg gcaaaaaggg cagatgattt
    11401 tactgctgat aatttaaaga acataaaaga agaaataaaa aatacattaa atatacaact
    11461 aggtgaaaat gtaattcaaa atatatattt cacaaatata gtagtgcaat aaaaggatgg
    11521 taagacatga tactttattt actaaaaata ttaatatgta tcccaataat tttaatattg
    11581 atagtcttat ctttaaaaat tagccaagga actttattaa aaaaatataa tgataaatat
    11641 gtaaaaatac tagatattgt aaatataagt aaaaacaata gcataataat tttaaaaata
    11701 ggtgaagaag gatgcattat ggcatcttct tcttctagca tgagtaaaat aaaagatttg
    11761 accaaagaag aaatattaaa aatagaaaac gacattaaag aaagaaattt taaaattcaa
    11821 gattttaaaa tggaaagaat taaaaagaaa tatgatttca gtagatatat tggaaaattt
    11881 acaaaaaagg aagataagta aatggaacta ttatcaaaat tacctttggc tgatgtacca
    11941 tatacaagtt caatgcaatt gtttttattt ctaactgcat taatgttttt accatttgta
    12001 atgttcatga tgacaagctt tgtcagaata gttataagtt tatcattttt gaaatcagca
    12061 ttaggagcac agcaagcaat tccaagtcaa attttggtag gacttgcaat agtattgaca
    12121 atatttataa tgagaccagt attaaatgag ataaacgaaa aggcattaca accatatatg
    12181 aaagaagaag ttactatgga agaagctatg aaggaagcag aaggacctat taaagagttt
    12241 ttattaacac aaaccagaca gacagattta gatttatttg tagaacaggc tggtttaaaa
    12301 gaaaagaaat taactcgtga aaatatacca ctatctgttg tagttccagc atttgctata
    12361 agcgaactaa aaactgcttt tcaaataggt tttttaatat atataccatt tttgataata
    12421 gaccttgttg tggcaagtgt tttgatgtct atgggtatgt ttatgttgcc tccagtcatg
    12481 atatcattac catttaagtt attattattt gtaatggtgg atggatggaa cttgatagta
    12541 aaaacattga tattgggatt tggataggag aaaaatagta tgagtgaatt tatgataatg
    12601 agtgttctta aaaatggcat gtttacagga gctatgattg cagctccagt actcattgtt
    12661 tctcttgtag ttgggctttt aataagtgtg tttcaagcta caactcaaat ccaggagcaa
    12721 actttgactt ttgtaccaaa actaatagct attcttttag tagtagctat tggtggaagc
    12781 tggatgttac atactcttat tagttttact tctgagatat tcaatatgat atctcttata
    12841 actaaataag taggatacat atgatttttg tatttattag aatagtagca ttctttggaa
    12901 cactaagaat actatttcca gctggtacac ctgctttatt taagtcactc tttgcaatca
    12961 ttatatcaat attgatttca agtactatgc aaattgaata tgcaacaaat atagacaaca
    13021 ttgtattgtt taccttatat ggtgtaaatg agaccataac tgggattatg cttggatata
    13081 taaccaacct atgtttttat agtatcagaa tggcgggttc tatgatggac caacagatgg
    13141 gattatcaat gattaatatg tttgacccaa attcaatgac tcagacaact ttaattgata
    13201 atcttatgaa ctggacagca cttatgatat tttttagcat ggatggtcat catgttttaa
    13261 ttagaggtat aaggtatagt tttgagttaa ttccaatagg aaaaccattt gtagataata
    13321 acatagatta tataataaac atatttgtgc agtgcttttt aactggattc aaaatagcaa
    13381 tacctattgt actttgtctg cttatggcag attttatttt agggcttata tcaagaagtg
    13441 tacctcaatt aaatgtaatg atagttggta tgccattaaa aatattggtt ggtattgcat
    13501 tatttatcat atcaatacct ttaattgtca atcaaataag tcatttatta agtcaaatac
    13561 caaagatgta tgagggaact tttgcactag ctcctatgtt ttttatgggt tcagcagata
    13621 aaacagaaga agctactcca aagaaaaagg gagaacaaag aaagaaaggt aatatagcaa
    13681 agagtagaga attacccgtt gcaatgactc tacttgcatt caccttatta gtacctacat
    13741 tattttcata tgtagtagat acacttaaat cttcgcttaa ttattttttg agtctagatt
    13801 tttatatgaa cataaattat tcaaacctag agaaattagt tatagcagga ttaatggatt
    13861 tttttaagat atttttacca atagctattc cctttttagt tttaggcata atagcaaacc
    13921 tatttcaggt gggaatactg tttactggtg aaactttaaa accaaattta tcaaaattaa
    13981 atccaattag tggattcaaa aacatgtttt ctatgagaag tttgtcaacc ttaataaagg
    14041 atacagcgat tatatctatt ttggcttaca taggatatac attcttccaa gataattatt
    14101 tagatatatt aaagctaggt aacatatacc taccaacttt aatgtacaca gttaaagact
    14161 tagtatattc aatattgagt aagatttgtg tagctatgat agctatagca gttgcagatt
    14221 atgtttatca aagatacagt cataaaaagc aactgagaat gacaaaacaa gaagttaaag
    14281 atgaatataa aaactcagaa ggagacccag aagtaaaagc taagataaaa caaaaacaaa
    14341 gacaaatttc gtctcaaagg acaatgcaag cagtaccaag tgctactgta atagtaacca
    14401 atccaaccca cttatctata gcagtgagat atgaaaaagg gaaagaccaa gctccagtag
    14461 tggtggcaaa aggtgcagat tatctagctt ttaaaataag ggaaattgca aagggaaatg
    14521 acatccctat aatagaaaac aaacctattg ctaggttgtt atataagcaa gtagaaatag
    14581 accaagaaat tccagaggac atgtatcaag cttttgcaga gatattagtg gcagtatata
    14641 aaatcaaaaa tagatacaaa gtccccaaaa ggtaggataa gtaatgaata agtttaattt
    14701 aaaggaaaat atggatgtaa tagtggcatt tggtgttgta gggattgttc ttatgatgat
    14761 agtgccatta cctacattta tattagatat tttactggca attaacataa gtttatctgt
    14821 gctaatttta ctaatgacat tatttacaac aaatgtactt gatttatcta tatttccaac
    14881 agtgttactt gtgacaacac tatttagatt gggattaaat ctttcatcaa ctagattgat
    14941 tttaacacag ggatatgcag gtgaagttat agaggcattt ggaagttttg ttgtaggtgg
    15001 aaattacgta gtaggaataa ttatattctt aattatatta attgttcaat ttgttgttat
    15061 aaccaatggt tctggaagag tatctgaagt aacagctaga tttacgttag atgccatgcc
    15121 aggtaagcag atgagtatag atgcagattt aaatgcagga gttatagatg acaaaactgc
    15181 tagaaaaaga agaaaagagc ttcaacaaga agcagatttt tatggttcta tggatggagc
    15241 aaataagttt gtaaagggag atgccatagc aggtcttata gtaacagcaa taaacataat
    15301 aggtggaatt gtaataggag ctgtaatgct gaatatgact cttatgggtg cagcacagac
    15361 atatgtaaga cttactatag gggatggtct tgtaagtcag atacctgctc tattaatatc
    15421 tacatcagca ggtataatcg taacaagagc ttctactgat gaaaactttg gtgacttagt
    15481 aggtaaacag ttaacggcaa taccaaaagc agtaatgatg actggttgtg ttctaatcgt
    15541 acttggtatg atgcctggat tacctaaacc agcatttttt tcactaggta taggagctat
    15601 agcagcaggt tactttttag gaagagaaaa gaaagatact ttagaagact tggagtttga
    15661 aaaacctgat atggtaaacc cagataaaaa tgaagtagaa gatgtaacaa atttaataaa
    15721 tgtagaatca atagaagtag aaattggata tggtttaata tccttagctg atgaatcagc
    15781 aggaggagat ttacttcaga gaatagcatc aataagaaga caatgtgcaa tagatatggg
    15841 tatagtcgta caacccataa gaataagaga taacttacag ttaaatccaa accaatacaa
    15901 tataaaaata aaaggaaatg tagttggtgg gtatgagata atgcctaata tggttttatg
    15961 tatggaccct atgaatcaag gatttagtat atttggaata aagacaattg aacctacttt
    16021 tggaatagag gcactttgga tagaaagtga caaggtagaa gatgcagagt taaagggtta
    16081 tacagttgta gattcatcca caatacttat aactcactta ctagatataa taaaatcaaa
    16141 tgcacacgaa ttactgggaa gacaagaagt taagactatt atagatgcag caagagaaaa
    16201 ttatagtgct gtagtagatg aattgatacc agatttgatg acacttggtg aaattcaaaa
    16261 agtacttaaa aatctgttaa gagaaaaagt aaatataaag gatagagtta caatacttga
    16321 aacgcttgca gaccagtcta gaaatacaaa agatatagag cttcttactg aatatgtaag
    16381 aatagccttg gctagaagta tttgtaataa tttagttgat gatgataaga caattgtagt
    16441 ggctacattg tctccagaaa ctgaagagtt ggtatctaat aatttacaga ggtctgtaaa
    16501 tggaacttat ccagcagttg acccagaaaa tacaaataaa atatttgaaa gtatacaaga
    16561 agtaatgagc aatgtatatt tcaatcataa tataccagta atagtagtat caccaaagat
    16621 aagagctcca tttagaaaat tagttgaaat tgtatatcct aatttgactg tattatcatt
    16681 aaatgaaata cctaacgata ttaaaatcaa agcagaaggt gtggtgagca tatatgatga
    16741 cgaaaaagta tacagctaac acaattcagg atgctatgaa tctagccaaa atggaattgg
    16801 gtgacaatat tacattaata gataaaaaag aggtaagaaa gtctggaata caaggtatct
    16861 tttcaaaaaa agatattgaa ctaactattg gatgggaaaa gagagaaaat gtagaacaaa
    16921 aagatttaaa acgagagata gaacaattaa agtcaattat taacaatatg gggtttgata
    16981 ataagaatga taatgatata gataaaatat gtaaaaatct actaagttta gaattgaatg
    17041 aagaaattgt agaatctata agaattgatt tgcaagaaat gaagttcaat ggaatcgata
    17101 caagtaaaaa tttagtagaa attttaaaga aaaagattaa aatagaaaat caagtaataa
    17161 atggtaaaat tgctctagtc ggaccaccag gagtaggtaa aacgactaca atagcaaagt
    17221 tagccgcaaa attagttttt gaagaaaata aaaaagtagg agtaataact atagatacat
    17281 acaggattgg tgctgtagaa cagttgaaga tatatactga tataatgaat attcccttta
    17341 aaggggtaat aagtcctgat gaaatggaat tggcacttga cgagatgaaa gattgtgatg
    17401 ttgtattaat agatacaaca ggtagaggct acaaaaactc tatgcaaata ctagaaatca
    17461 aaaatcttat agataaagct gaaactgata atatacattt agttttgaat tgtacaacaa
    17521 gagaaagtga tacaaaagca attatagatt catatagaaa tgtgaatttt aaaagcttaa
    17581 taattacaaa gctagatgaa acaataacat atggctcaat atttaacata atgaattatg
    17641 cgcaaaaacc aatatcatat attacaacag gacaaaatgt tcctgatgat attataaaac
    17701 ctaatgaaga taagattata aggttactat taggagttga aagtatatga tagaccaagc
    17761 tcaaattttg agaaaaatag caatggaaaa aagaggactt gatgagttta tagtagagaa
    17821 tgagaatgta cctaagataa ttacaatagc ttctggtaaa ggcggtgttg gaaagagcaa
    17881 tctcgctaca aatttgtcta tatgcttgac caaacttaat aaaaaagttc ttatattaga
    17941 tgcagacata ggaatgtcta atatagatat aataatgggg gtaaatgtaa aagggactat
    18001 aattgatgta attaatggcg aaaaaaatat agaagatata atttcacaga ctaagtatgg
    18061 tgtaaatata atatctggag gttctgccct taatcatata gaagacttta cagaagctca
    18121 aagaaataag tttatacata gcatagaaca aattcacgat gtggatttta taataattga
    18181 tacaggagct ggtatgagca aaagcctatt gtcatttata tactgtagta ctgaattttt
    18241 cttaataaca actccagaac cgacatcatt gactgacgca tatagtttat taaaagctat
    18301 aagtaatttt ggcataaaga gaagtgcaaa tataataatc aatagggtaa ttgatttaga
    18361 agaagcaaaa tctacataca aaagaataaa aatggttgtg gacaaatttc taaaccttaa
    18421 tctagaattg tatggatata taatagatga caaaaaagta agtttatgtg taaaaaaaca
    18481 gataccattc attttagaat atcctacaag tattgcatca aaatgtatta tagccatagc
    18541 aaagagaatg gtaagtcagt caagagaaga tattgttgat aataaaagtt ttctaagaaa
    18601 gatgtttagt atatttaaaa gctaaggagg cgtagttaat gaatagagaa gaattaataa
    18661 aagagaatat gcctcttgta aagagtatag caagaaaatt ttttatacca gggaaaggtt
    18721 ttgaatatca agacttagta aatagtggag tcattggatt gattgatgca ataaataaat
    18781 ttgatgctga aaaaggggca aagttttcta gttactctta tataaaaata aaatctgcta
    18841 tattagatga aattagaaat caaagtccaa tttctaaaca taatctaact aaagtaaata
    18901 agtataatag agtggtagaa aagttgcaat ctaaattatt aagagagcca acttcatatg
    18961 aaattgcaaa agaattaaag gtttcagaaa aagaacttca tgatatcgaa agtaatatag
    19021 atatgttaaa tattgtatca ttaaactatg taatctttga agatacaaat gaaactgtac
    19081 aagatgtaat aagtgataga gaagaggaag ctccagaaaa tataatagaa gaagaagaaa
    19141 agttagagat tctatccaaa gcaattagta atttaaatga aagagaaaaa ttaatacttt
    19201 cactgtacta ttatgaagat ttaaatctaa aggagatagg gaaagtgcta ggtgtttcag
    19261 aatcaagagt ttcacaactc cacagaaaat caataagaaa cttaagaaac aagataaaag
    19321 aacttaaata ttctatatag atggtgattg ataagatgat acaaattata ttaatagtag
    19381 tgtctatttt aataatagta actatagtta taaatttaca taaggaatca aaaaataaag
    19441 ataacagata ctttgataaa atatttgagc aagaatatga agcaaatgat agattaataa
    19501 ttgcagaaaa aagaagattc tttttagaca aagtacttgc agaaaaaaga attaatagtc
    19561 atataaaagt ttatgaaaat tataacctaa taaaggctaa tgaagaaaga aaggaaaaca
    19621 tatttataga atcaaaaaag gaagtaagac aagaaaatga gttatctctt aaagtgaaac
    19681 atcttataag ttcaggttat gatgatgtgg aaatatgtaa gatgctagat attggaaagg
    19741 gggaactgtt attaataagg agttgttaca aaatataagg atattattat gtgataaaaa
    19801 agtattctta ggaataggta ttggtatatt aatatcaact ttatgtataa tgctttttag
    19861 taataatgat atgagtaagg cagagataga aaaaaaggcc agagcgttag gcatgaaata
    19921 tacaagtgag atgaaagttt tagaatagat gatattgttt agacatttac aaaaaaggag
    19981 gtcataatgt gataagagga ttatatacag cagtttctgc tatgataact aatcaacaaa
    20041 agcaaaatgt tgttgtcaat aacctagcta atatggatac aaatggatat aaaagtaaac
    20101 aacttttgac taaaagtttt gatgaattaa agttggaggg ttacaataac tacgcaaatg
    20161 gaactaaaca aaagcagatt ataggcgata taagtccagg tatttctatg gatgaaacta
    20221 tcacaaattt taatcaagga cctataaaaa ctactgataa taaaatggat gtagctattc
    20281 aaggtaaggg attttttcta gttagtgatg cagctggaaa tcaattttac actagaaatg
    20341 ggaacttcag aacagacaat caaggtgacc ttataacaag tgaagggtat tatgtacttg
    20401 ggacgaatac tgctactggt gctgtaggtc atataaatgt aggaaatcaa aaatttgaag
    20461 tggcaaaaga taatacaata tcactagacg gaaatgctat gtataaattt aatattgtag
    20521 attttaataa ctacaataac ttaaaaaaag aaggagataa cttatattct ggaggaggag
    20581 ctatgaaagt aaataatgca cttacaatac aaagtgcgat agagtcctct aatgtagata
    20641 tggtatctga aattaataat atgatgacaa tatcaagaga atatgaggca aatcaaaaga
    20701 taattcaggc tatggattct aaattagcaa aaatagcaag tgagattggt tcagtaagat
    20761 aggtaatagg aggtgaattt ttatgtacac aatgttttat actagtaaaa cagctttatc
    20821 agcaaatcaa agtaaactag atataatatc taacaatata gcaaattctg attcaacagg
    20881 atataaaaaa ataaatatgg aatattctga tttagtggat gaagtactaa atagaccatc
    20941 atatcctaca aatggcaatg atatatcgac tggaacagga gctaaggcaa cagctcccat
    21001 gagaaattat gaacaaggtg cattggctcc tacagatagt aagagtaatt tggcaataga
    21061 tggagaagga ttctttagag tgataagaaa agatggtaca tatgcatata caagaaatgg
    21121 tggatttaat gtagatgctt taggtaagat tgtagatgat aatggaaata tattagatgt
    21181 ccaatttgat gcaggatata actataataa tacaaatata gatagtacaa acctgacagt
    21241 ttcaagaaat ggagagctat tcgtagataa taaaaaaata ggaaaaatca acttatatca
    21301 acctatagga actcaaaatt ttatatctga aggagatagt ttattcgtcg caactgatgc
    21361 agcacagatt aaacaagttg agaaagtcga tatagttcaa ggctatagag agaggtcaaa
    21421 tgtttcttta caagaagaat ttgttgactt aatagccact caaagagcat ttcaaatgaa
    21481 ctcaaaggga ataaagacag cagatgaaat gtggcaaata gcgaataatt taagagctaa
    21541 ataattatgt aaggtgagga atattcatga atgatatgaa agagtacgat tttggcaaac
    21601 ctcagagtta ttcaagagaa aatttaactt gtttaaattt tttattagct gaattttgta
    21661 aaaaatataa aaactatata atttatgaac ttaagtgtaa ttctagtatg gttgttgata
    21721 gtatagacca agtaaattat cagacttttt tagatagagt aacttcttca tgcgtagtag
    21781 tacaaaatgc aatggaacct gttatgaaaa acttttcttt tagaatagat agaagtgtag
    21841 ctgatatgtg gattgatata acttctggag gaactggagt tgtaaaggat aatgatagag
    21901 aacttacaga acttgataaa aaagtgcttt tacaccttat ggatgattta gtaagaaata
    21961 tgcacttatt tgagggtttt gaaaatatac aagtattgga tacacataca catattaatt
    22021 tgccacaatt atgttctcca actgcaccag tatgcgttgt agatttaaaa gtgctaaatg
    22081 ataatgagta tattggaagt gtttctcttt gctttccata caatggttta gaggctctgt
    22141 tagaaagtat atctgttata gaattttttg ataatgatgt aggagatgat tcagaggaat
    22201 ttacccaaaa aatctataat agtgtatcta atatagaatt atcagttatt gcagagatag
    22261 gaaaagtatc aattaatgtt gaggatttac tcaaactaga agttggagat gtaatagtaa
    22321 caaataaaaa aataaatgat tatatagata tatttgtaga aaattcaaaa tcatacacag
    22381 caacaccagg atttatatca agtaaaaaag gtgtaaaaat aaatgatgct gttggaaaag
    22441 aggtgtagtt atggacaata gtaatcttat ttcagatgaa gaagcaaaga tgttattaaa
    22501 tgataaagtt gaaagtgaag ttgatggaga tgatgagtta gccttagatg tctctgaagt
    22561 taatcgaaat aatatacaaa ggatacttga ccttaagtta gaattatctg tagttatagg
    22621 aagaactaag atgactctaa gagatatttt aaatttacat aaaggttctc ttattgaact
    22681 ggatactttg gcagaccaag atgtggaaat actaatagat aataaggttt tggcttatgg
    22741 aaaagtagtg gtggtagatt taaattttgg tgtaaagata acaagtatag taagtgaaga
    22801 agacatggta aaatctcttg tttagagata acatcaatta atacttaagg catgaggtgg
    22861 tacttatttt aaacttaaat gatataaaaa aagatatact aaaactcaat aaaaaagact
    22921 catgttctct atataatgaa tctattaata atataaataa taattgtata tcaactggat
    22981 taaaattttt aaaacaagca agagatttaa acccagatga tgttgatata ttaaatctca
    23041 caggtcttgt aaacttacta aaatgtaatt ttgatgatgc tgtagaaagt ttctataaga
    23101 gttcactttg tgaaaaaact gctctgtgtg aaaagtatat aaacatgctt acatctgagg
    23161 agtttttaat tttctttgaa aagtacaatc aacttataag gttaataaat aaaggaatgt
    23221 ataaagaagc tatacaaggg tttaaactta taactgacca atactgtgat ttaatagaac
    23281 cttatgagtt gcttgcctta ctgtatgaca aggaagaaga atatataaaa tttgatgaat
    23341 gtttagaagt attgaagatt attgataagg aaaattattt attaaatcaa gaaaataaca
    23401 cattatatat gtataatagt gctaatatac aaactaaaag taatataaaa gtagatgatt
    23461 ataagaatga gttcttacat aaaagtagta gtaaccataa aattaatgat tataatgatg
    23521 taactaaaga aaagagttca agcaaaaacc agaaaagttc agattctaat aagaaaaaaa
    23581 gtattaaaaa aaataagtac ctatatatag ccataatatt aggaatatta ttagtaggac
    23641 aaagtatata tagttcttat aagatgaata atttaactga taaaatatct aaaaataatg
    23701 aaactaaaaa tgaagagtca atagattcta acttgactaa gaaagaaaat aatatagaag
    23761 aaaatgaaga tatgagtaag gcttctaata taaataagag taataaaaac attaataaag
    23821 aggatgatgt aaaatctaaa aaaaatactg tagaaaatga agatgataaa gattctgact
    23881 tatttacaga ggatgaattg atgtctaagg cgaatacttt aaaatcagaa aagaaaacta
    23941 aatcttctat acaactatat aagaaagttg cagatatagg tgaaaataaa gggaatacat
    24001 ctgaagcaac ttatcaagtt gctattctca gtgaaaagtt aaaagactat aaaactgctg
    24061 aagaatatta taaaatgtat gtagaaaatt actcagaaaa agatgcttat tttgatgaat
    24121 cttattataa tttaggtatg atgtactata acaatggtga tttaaaaaat tctaaattga
    24181 cattaaagaa gttggttaat aaggtaccaa atagtatgta taataattca aaagtaaaag
    24241 aaattttaaa agaagaatag ttaaattaga taagaaaaat aaattatttt attttaaaat
    24301 aatatgatta taatatattg acataccatt ttaaaaaatt taaaatatta attataaaat
    24361 gaggagggat aaaaaatgga atttgaaaaa gggagtattt caattcatac agaaaatatt
    24421 tttcctataa ttaaaaaatg gttatactct gataaagaca tatttataag agagcttata
    24481 agtaatggat gtgatgcagt aagtaaacat aaaagacttg tatcactagg agaaatatca
    24541 gaaaataagt catcagatta taaaattaca gtatctgtaa ataaaggaga aggtacactt
    24601 aaatttattg acaatggaat tggtatgact gaagaagaga taaaaaaata cataaatcaa
    24661 gttgcttttt caggtgctga agatttcttt aataaatata aggataaaat ggaagagtca
    24721 aatgatataa taggtcattt tggattagga ttttattctg catttatggt gtctaaaaag
    24781 gtacaaatag atacactttc atatacagaa ggagcgactc ctgtaagatg gatatctgaa
    24841 ggtggtacag aatacgaaat atctgaatca gatgctagaa atgatagagg aactactata
    24901 acactattta ttgatgatga tagtaaagaa tttttagatg aatttactgt aagaggaata
    24961 ataaataaat actgttcttt cttaccagta gaaatatatt tagaagatgt tgaaagatta
    25021 gaaagagaag ctaaagaagc agaagaaaaa gctaaaaaac aaaaggaaga tggaaaagaa
    25081 gagattgtag atgcaaaagt aattgagcct ttaaacgaca ctaatcctct atggttaaaa
    25141 tctccaaaag actgtactga tgaggagtat aaagagtttt atagaaaggt attcaatgta
    25201 tttgatgaac ctttattttg gatacattta aatgtagatt atcctttcaa tttaaagggt
    25261 atactttact tccctaaatt aaaaaatgag tttgaactga ctgaaggaaa agtaaaatta
    25321 tacaacaatc aagtgtttgt ggctgacaat ataaaagaag ttataccaga atttttactt
    25381 ttattaaaag gagttataga ctgcccagac ttaccattaa atgtatcaag aagtttctta
    25441 caaaatgaca gggatgtaag caaaatttct aaacatataa ttaaaaaagt agctgataag
    25501 ttgaaatctc tttgtaaaaa tgaaagagaa gaatacaata agttttggga tgatatacaa
    25561 atatttatta aatatggttg cttaaaagat gaaagtttct atgagaaggt aaaagaatgt
    25621 atattattca aaactattga tgatgagtat ataacattac aagattattt agaaaaatgt
    25681 aaggacaaac atgaaaataa ggtattttat gtaagtgata aggaacagca atctcaatac
    25741 attaaactat ttaaagaata cgacttaagt gctgttgttt taaactcatc aatagatact
    25801 cattttattt catttatgga atataaagag aatggagtta agtttaatag aatagatgca
    25861 gacctttctg atgtattaaa agataaaaat gaaaataaag atagtgaaga aaacaaagaa
    25921 gagatagcta agatagaagg tctgtttaaa gaagctgtcg gagaaagagt gaagaattat
    25981 tctgtagaag gattgaaaaa tgaagacact ccagctatgg tattagtatc agaacaatct
    26041 attagaatgg cagaaatgca gtcaagattt gctggaatgg atttaggaat gaattttgag
    26101 gaagaaaaaa ctcttgtaat aaatgagaac agtccaataa tcaaaaaatt ggtttctctt
    26161 aaagatgatg aggaaaagaa agataagatt acgcttattt gtaaccagat agcagattta
    26221 gctttacttt ctaataaaga attaaagcca gatgagttag attcatttgt acaaagaagt
    26281 aataagctta tgagtctttt gatagaatta taagattgaa tttgaataca ttgaagcaaa
    26341 tttataaaaa gtattcaata tcagtgataa gaaagaagtg tctcaaaatg aacttttcag
    26401 ttcatgaggc gcttttttta tgtgaaatta aatttatttt aatcatttca acaatgaaaa
    26461 atatatttat ctctattttg agacagacca ttctttattt ttttatcttt ggttaatttt
    26521 aaatatttaa gtaggttcta ataaaaaact ctatttagtt aaatatagtt aacttgatat
    26581 ataataagat aatacatata attaagtaaa agattgtttt ttagtttatg tttaaataca
    26641 taattacact ttgttaaaaa cataaaatta ttactaaagt agaaatagga ggttttagaa
    26701 tgaattttaa ttataatttg ccagtaaata tcttatttgg gagaggcaga attaatgatg
    26761 tgggaaaaga agtatctaaa tatggcaaaa aagtattgat agtaacaggt aaaaatagta
    26821 caaagaaaac tggattactt gataaaacaa tagatttact aaaagactct aaaatagaat
    26881 atgaagtttt tgatagagta gaacaaaatc ctcttataac tactatatat tcaggagtag
    26941 aaattataaa atcaactgga tgtgattgtg ttttaggtct tggtggtgga agcattatgg
    27001 atgctgccaa gagtatagct ttttcttata aaaacccagg agatttaaat gattatatat
    27061 ttggaattag acaaggtgaa gaagctttac ctataatctt agttccaaca acatcaggta
    27121 caggtagtga aggaaattgt tttgcagtac ttacaaattc agaaactaaa gataaaaaat
    27181 ctataaagaa gaatagtatg tatgcaaaag catcaataat tgacccagaa cttatggtta
    27241 caatgccaaa acatataatt gcatcagttg gatttgatgc acttgcccat aatatggaag
    27301 catatctttc taatggaaga aaccctcttg cagatgtaca agctatttat gggattgaac
    27361 ttatatcaga aaacctaata aaggtatata atgatgttaa tgatttagaa gcatgggaaa
    27421 aaataacact tgcaagtact attggaggaa tgacgattgg tacagcgggt acagccttgc
    27481 cacatggaat ggagcatcct gtaagtggtc ttagagatgt aatgcatgga aaaggacttg
    27541 cagctttgac tcctactatt atagaaagtt catgggatag tgatattgaa agatttggta
    27601 atatttcaaa ggtattagga ggaacttgtg cagaagattg ttcagatgca attagaaatt
    27661 tccttaaaaa aatagattta gatataaaac taagtgattt aggtattgaa aaatcagata
    27721 tagattggtt aactgataat tgtatgaaaa tatcagttgc aaatattaag agacatccaa
    27781 agtattttaa taaggaacaa ataaaggaaa tgtaccataa gtctttataa tttgacttta
    27841 catatttagt tttatataaa aattataaat taataataaa aaattataag taattaatag
    27901 taaaaaaatt gtgtatagaa gttatatata taataaattt gtcttaagct tttattttac
    27961 tttctaataa ataaaggagt ttaaaaaagg gaagattaat taagtaatat tttataaaat
    28021 tcttcgattt aaaaacttta agtagaggtg aaataaatgt ttaatcccaa aagaataata
    28081 ttcgaaaaag gaactttaga cactgatgtg ggtaaaaaaa tatacaataa atttagagat
    28141 aataaagatg tagagataat taatatatca tcaaatagga ttaaagaaca tattccaggt
    28201 gaaaatctat atgaacaata tagaagtggg aagcagacta tggtagttgg gattagaaaa
    28261 agtctgaagt ttcaaacatg taaaccttct gctaattatc aactaccact tgtcagtgga
    28321 tgtatgggaa gatgtgagta ttgttatttg aacacacaat taggtgataa accatttata
    28381 agggtgtttg taaatgtaga tgaaatactt gaacagacaa aaaaatatat tgaagataga
    28441 aagccacagg taaccatatt tgaaggggca gctacatcag acccagttcc agtagagcca
    28501 tatactaatt ctttaaagaa aacaatagag ttttttggaa gagaggaaaa aggaagattt
    28561 agatttgtta ctaaatacag tgatgtggat agcttattgg atgctgaaca taataatcat
    28621 acagaaatac gatttagtat caatactcct agaattataa atgaacatga gcattataca
    28681 gcctctgcaa ataaaagaat agagtcagct gtaaaacttg ctagggctgg ttatcagatt
    28741 ggtttcataa tagcacctgt gtttttatat gaaggttgga aagaagagta taaaaatctg
    28801 attataagta taaaagaagc tttaccaaag gattttgata aaaaaattat atttgaagtt
    28861 atatctcata gatatacaac taaagcaaaa aatagaatac tagagattta tccagataca
    28921 ctattgccaa tggaaaatga ggatagaaag tttaaatacg gtcaatttgg atatggtaag
    28981 tacgtgtatg ataaagaaca attagatgat atgaaagagt tctttcttaa ggaaataaat
    29041 ggagtattta aaaatagttt aataaaatat ataatatagc aaatcttacc taaagatttg
    29101 ctatatttta tttttataca ttttatgttt ataataaagc aatgagattt agcactatca
    29161 tataagaaaa ttaaaaaggg cactatctat caagaacatt ttttctagtt ttgatactat
    29221 aaaggataag agtaacaaaa atatcaggag gagttatagt atgcatgcat gggagtctat
    29281 tcaaattaca ttggatttaa tagaagcaaa tttatcagaa gaaatatcaa ttaatgaatt
    29341 agcaaataaa gcaaatttat caccatttta ctatcaaaga ctatttaaaa gattggtaaa
    29401 taagactgta atggagtata taaagcttcg tcgtcttgca agagcttctg aatacttagc
    29461 agaacataag aatcgtatac ttgatgtagc tttaaatttt ggatttgcta gtcatgagac
    29521 atttacacgt tcctttaaaa aagcatatgg attaactcca gaaaaatata gagcaaatcc
    29581 agtaaaactc aatcacttta ttaagccaga attaatttta aattatgcta tggttgatga
    29641 aggtgttcca ctgattgcag atgatatagt gattgaagtc aatcgtaaga cattgagtaa
    29701 tccaaggaca tttgttggaa tagaaataga agtacctatt tgccagttgg tgggcggtga
    29761 aacaactgga attgcaatag tagaggaatt atggatgaaa cttggaagtc aaagacataa
    29821 tataccaaat caaattccag gtggaaatga atttgctgct ctttatatgg gaaatgcaaa
    29881 agaaggaaat tgtatgtata tggcaggtgt agaggtagag tcaggtacat cagtagaagg
    29941 atatagtact tttgagttgc cagctaaaga atatttagta tgtggatttg aggcagaaaa
    30001 ctttaatgag ttagttaatt cagctgtttt taaagcagat aaatttatgg aaagatggat
    30061 gaagaaacat aatttaacaa ctactgattt tgcaattgag atgtattacc ccactacacc
    30121 tgaagcagca tatctggaac attggattgt tccggttcct attgaacaat agaaaggatg
    30181 atgaatatga attggcaaga tgcgtttttt caagatacta aacctacatt tgagcaaatt
    30241 aatgaattta ttaataatcc attatgggac aagttaaata aaactttggt ttctacttat
    30301 aatgtagaac ctaagcttga atacagtaaa tgttcaatgc aaagaggttg gaatgtaaaa
    30361 tataaaaaaa gaggtaaatc actatgtact ttatatccac aagaaggtta ttttaaagct
    30421 ttggttattg taagtgaaag caatagagta gaggttgatt tatttattaa tacttgttgt
    30481 gattatatca aaaaaatata taatgaggta aactttttta atggaagtaa atggctaatg
    30541 attcaagtag atagtttatt ggtattaaac gatatgcttg aactaattaa atttagagct
    30601 taacatatag aacaggatga atatataagt catcctgttt ttatattcaa tcagataaat
    30661 taatatatag tctataatat gaataattta gtaaatttaa atttacttta tctttctaca
    30721 ttctttgcaa ctaagtccac atgtgttttt ttcttgcata ttagtagcac cccaattagc
    30781 aaattgttgt aaaataggca caatactttt acctttactt gttaatgtat attcaacttt
    30841 tggaggaatt tcattatatt gtttacgatg aacaatacca gtagactcta aatcttttaa
    30901 tgattgagct agcatagtat ttgtaatgcc atccaatttt ctttttatgc tactatatct
    30961 aattggattt tcaactgcta acatacatat aataggtaat ttccacttac caccgacaat
    31021 gtctaatgca taacggattg gacaggttaa ttcttcaacg tttttagtta tatttttttc
    31081 agtatttata ctcattttaa ttactcctta gttatagtag tatctttttt atactttatc
    31141 agaaaaaact gcatacttgt tttttctgta ttttatatta aaattatatc aaaggataat
    31201 ccttaataca agtatttaaa aggggtgtaa gaattatgaa agcattagaa tttttgaaca
    31261 aggcacgagt ttattattta gcaacagttg atgagaacaa tcaagcacat gtgcgtcctt
    31321 taggatttgt tatggaatac aatggtaaac ttacattttg cacatctaat caaaaggata
    31381 tgtttaagca acttattttt aatccaaagg ttgaactttg ttgtatagac caaaacctta
    31441 atactctacg tattttaggt gaagcagtat ttgttacatc aaaagaaaca caagctaagg
    31501 cacttgaaat aatgccaagt ttaggtcaga tgtactctgt aggagatggt aagtttgaaa
    31561 tattctctat tgataaggca aaagttagtt gttgttcaat gagtggtaaa aagattgatg
    31621 tagagcttta attataattg aatcgacatc catagtgaaa attaagaaaa cgttattact
    31681 gaaatgttga tagatttaat ttaaatgcaa taaaaagatt tttaaataat gaatatgtaa
    31741 aaatttttag ttattagatg tgtatttcaa taatgatata ctattttgaa taattacata
    31801 ctagaaataa gataattaaa atttacttta taatgggata gatttctttt aaaaaatatt
    31861 ttaactataa ttgattttta tttaatctga aaaaaatatt atgactataa aaaattgcta
    31921 cttattattt ggatattttt atatataaat aataagtagc atgactttat acattaataa
    31981 tgatagaata taaattaata gataagatat gattttaaaa ggagtgatat aagatgagta
    32041 aatatagttc tttatgggaa tattttaaga aaaacaatag tcaatcgttt aaattaactt
    32101 ttgaagaaat aaaagatatt gctgggatag agatagacca ttcgtttttg aaatataaaa
    32161 aggaattaaa tgaatatgga tatcaagtag gaaaaatctc tttaaaagag aagactgtta
    32221 ttttcgataa aattggttaa gacataaata attacatata ataaaataat ttgtattgat
    32281 gattattaca aataaaaaag ggcgtagcac tattttttag tgtcacagcc ccttttttgt
    32341 ttataattat gtacatttca cattatcacg atataagcat ttttcttatg agaaaattaa
    32401 ttagaattat ttttattcat atttaaatta tttaaattgt tttcccagtt ttttatctcc
    32461 tttttaactt cttcacttaa agtatcactt gaagatattt tctttaattt atcattcaaa
    32521 gatttctttt gttcctctga aaggtctgtt tttattgtag gatcaataat atctattaca
    32581 tcttttacat caaaatcaac aaatttgcac agttcttcta gatgatcaat tagaaaatct
    32641 agaccttcat atgaccattc tttataatct tttccgtttt ttaatagaaa ctcattcact
    32701 tggtaattct gatttgctaa ttcaaagaat gaacctgaag gatccattat atcatttata
    32761 gagttttcat agttaacaat attaatttgt cttattaatt tctctttttc tgttaagttg
    32821 ctataattct tgttaacaaa agctactaat ccaaattcaa agtttaaaat tgaatcttta
    32881 cgttttttta ctgaatcttc tccaaattcc ctaagacctt ctaaattttt atcaatggct
    32941 ttatctctaa tctctattaa ttgttctata cttaaacctt ctaagttttt aggtactatt
    33001 tcttcattat tcttagtaac ttctttcaat ttattgttag tatttttatt attgaaaata
    33061 aatatagcag ttaataaact taaaattatt actaaaataa ttaaacttac atttttttta
    33121 cttaacatat taaacctcct tttttaaata agtattgtac ttgtgaaaaa taaatttgtt
    33181 tatgaagata acatttacta ctgtttgttc taaagattat aatagaatat ttttttgata
    33241 taatctatat ttttcttatt aaattttctt attagatatt taatatcaat attttttaga
    33301 tagaaaagat tttaataact ccaaatattt aataagtaaa ataaa
//
LOCUS       DAGQVA010000047        30988 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.047, whole genome shotgun sequence.
ACCESSION   DAGQVA010000047 DAGQVA010000000
VERSION     DAGQVA010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30988
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.047"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..965)
                     /locus_tag="MIV85_002340"
     CDS             complement(<1..965)
                     /locus_tag="MIV85_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBY2961672.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDE"
     gene            complement(1013..1873)
                     /locus_tag="MIV85_002341"
     CDS             complement(1013..1873)
                     /locus_tag="MIV85_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBY2961673.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2142..2351
                     /locus_tag="MIV85_002342"
     CDS             2142..2351
                     /locus_tag="MIV85_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBY2961674.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2351..2617
                     /locus_tag="MIV85_002343"
     CDS             2351..2617
                     /locus_tag="MIV85_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBY2961675.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2646..3218
                     /locus_tag="MIV85_002344"
     CDS             2646..3218
                     /locus_tag="MIV85_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBY2961676.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3453..4643)
                     /locus_tag="MIV85_002345"
     CDS             complement(3453..4643)
                     /locus_tag="MIV85_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBY2961677.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKISYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4903..5334)
                     /gene="dut"
                     /locus_tag="MIV85_002346"
     CDS             complement(4903..5334)
                     /gene="dut"
                     /locus_tag="MIV85_002346"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBY2961678.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5447..7675
                     /locus_tag="MIV85_002347"
     CDS             5447..7675
                     /locus_tag="MIV85_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBY2961679.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7786..8271)
                     /locus_tag="MIV85_002348"
     CDS             complement(7786..8271)
                     /locus_tag="MIV85_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2961680.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8523..9746
                     /locus_tag="MIV85_002349"
     CDS             8523..9746
                     /locus_tag="MIV85_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBY2961681.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9750..12884
                     /locus_tag="MIV85_002350"
     CDS             9750..12884
                     /locus_tag="MIV85_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBY2961682.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12918..14216
                     /locus_tag="MIV85_002351"
     CDS             12918..14216
                     /locus_tag="MIV85_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBY2961683.1"
                     /translation="MSKIVAISCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14505..14750)
                     /locus_tag="MIV85_002352"
     CDS             complement(14505..14750)
                     /locus_tag="MIV85_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBY2961684.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(14964..17591)
                     /locus_tag="MIV85_002353"
     CDS             complement(14964..17591)
                     /locus_tag="MIV85_002353"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBY2961685.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17652..18494)
                     /locus_tag="MIV85_002354"
     CDS             complement(17652..18494)
                     /locus_tag="MIV85_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBY2961686.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18501..19139)
                     /locus_tag="MIV85_002355"
     CDS             complement(18501..19139)
                     /locus_tag="MIV85_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961687.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19575..20867)
                     /locus_tag="MIV85_002356"
     CDS             complement(19575..20867)
                     /locus_tag="MIV85_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBY2961688.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(20904..21260)
                     /locus_tag="MIV85_002357"
     CDS             complement(20904..21260)
                     /locus_tag="MIV85_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBY2961689.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21295..21654)
                     /locus_tag="MIV85_002358"
     CDS             complement(21295..21654)
                     /locus_tag="MIV85_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961690.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21723..23696)
                     /locus_tag="MIV85_002359"
     CDS             complement(21723..23696)
                     /locus_tag="MIV85_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBY2961691.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(23918..24931)
                     /locus_tag="MIV85_002360"
     CDS             complement(23918..24931)
                     /locus_tag="MIV85_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBY2961692.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(24944..25489)
                     /locus_tag="MIV85_002361"
     CDS             complement(24944..25489)
                     /locus_tag="MIV85_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBY2961693.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            complement(25865..26734)
                     /locus_tag="MIV85_002362"
     CDS             complement(25865..26734)
                     /locus_tag="MIV85_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2961694.1"
                     /translation="MDYLKYFKKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            complement(26886..28001)
                     /locus_tag="MIV85_002363"
     CDS             complement(26886..28001)
                     /locus_tag="MIV85_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBY2961695.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            complement(28237..29373)
                     /locus_tag="MIV85_002364"
     CDS             complement(28237..29373)
                     /locus_tag="MIV85_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2961696.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            complement(29429..30892)
                     /locus_tag="MIV85_002365"
     CDS             complement(29429..30892)
                     /locus_tag="MIV85_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBY2961697.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
BASE COUNT        10517 a         5267 c         3806 g        11398 t
ORIGIN      
        1 tcttcatcaa acatttttat tatatttttt atctcatact tgtactcatc ttcattcatt
       61 ctataaagca ttaaatcttc tagtacatct ttcatatcga agtacacatc ttctaataaa
      121 taaaaatagc cttcctctat atctttcaat ttatctatag tatccatttt tttacttata
      181 tctttcataa tttctaaatt ttgtatattt acatctatga ttgttaataa gtacattctc
      241 acagttttta ttatttcaac agaaaaatct acaatattat aatttccttc ttttttatat
      301 aatgactcct taaatttgtt aaaacaatta tctaaattag aatttatatc gttaaatggt
      361 ggtcttatta tgtcacgtat tattaaaaga ttttgtatat ctacattatt tgtgattgcc
      421 tcatccaaaa taaataaatt atatgcatca tttaatgggt catgggcatc tccactaaac
      481 tctaagttaa caaattcaag taaatttttc aatgatatat agttcataca tctcatacca
      541 caatttatat atttttcttt tatatctaca aataaatctc taatgttatt tacaaacctt
      601 ggatggttat tttttttagc acttctcata tctgtgttat tgaaacatgt caaatccaaa
      661 ttaccaaaag tatatattcc tttaatatca gaaaatatgc caagccattt tttaaacttt
      721 ctcatgacct cttcataact tggtgcactc ttcaattctt cagaagatat atgtgttaat
      781 tcttgtatat gaggatacaa ctcctcatta cttactggtc ttattaaaga tttaaattta
      841 tcaatatttt ttgttttttc atcatacata actgctccga ttgcaattat atcagaatta
      901 aatactgctc tttttgattt agaatttggc atattcattt caaaatctat atatactctt
      961 ttcaatataa acaccctttc caattgttta tagtgattct ttttaactat ttttattcaa
     1021 aattttctaa gaaagaatgt ttctccccat ctttttgcca accaagtact gaatcaagat
     1081 ttacattttc tgccgcctta aatatagatt tttctacatt tttaaaattt gattctaagc
     1141 tctttattaa gtcttttatc tcatatcttt tattacctgt ttttttagca gcaaccatac
     1201 atgcacaatt taatggccat ataccactat tttgaataaa tcttataata tgttcttctc
     1261 ttatataata aagtggtctt ataattttta taccttcaaa attagtagaa ttaagtttag
     1321 gaagcattgt tttaaaattt ccagcacaca ataaattaag cattgttgtc tctattacat
     1381 cgtcataatg atgacctaat gcaagtttgt tacaccctaa ttcttctgcc tttgaatata
     1441 atgctcctct cctcattctt gcacacatat agcatggata atcttttgct atttcatctg
     1501 ctatctcaaa tatccttgaa tcaaataaat gtattggtat atttagatac tcacaattat
     1561 ctataagtaa ttgtcttata tttgcatgat atccagggtc catagcaata aattcaacat
     1621 caaaattaac ttgtccatgt ttttttaact cttgaaacat tttagccata agaatactgt
     1681 cttttccacc agaaatcgct acagctatct tatcaccttc ttcaaccaat ttataatctc
     1741 ttattgcctt cataaactta gaccataaat ttttcctata tttttttatt atactttttt
     1801 ctatatctct tactggaagt ctttcctcaa aaggaactat aatttcacag ccttttcctg
     1861 atagttcact catctaatca cctcgtatat ttatgttaat aatattttac aaaaaagtct
     1921 accttcatcc acaaaatact ataattttta ctttaatttt actaaataat ttatagttta
     1981 caataacaca taaacttata ataacataaa taacctcttt cttttattat cttttttatt
     2041 tttctcattt aatattttat tattagtaac gatttttaaa tgattgaata ttatacacta
     2101 gatagagtta cctatctatt tacaacaagg aggttttcat cttggaaaat aagactagag
     2161 atatcaaaaa aaattgtggt ccatctttgg ctagaccata cattaataat caaattttca
     2221 cagaaatgta ctgcctttct gatgcattaa aatttggaac tatatttcca gaactaaact
     2281 tactagagtc tgaaatgtac aacaaagaat tatatgctaa gccaaaaaaa tatagaggag
     2341 gtagaagata atgaaagact catctagagc tgaacttatg agaaaagttc aggaaacatc
     2401 ttttgcatgt gttgatatga acttatattt agacaatcac cctgatgata aaaatgctat
     2461 caacacttat aattcattat gtaatcaatt tgcgcaagct agatatgctt acgaaaataa
     2521 atacggtcct ttaactaact ttgggtatgc tccaagtaga tgcccttggc aatgggctga
     2581 ccaaccttgg ccttgggaca gagaatttaa ttattagaca tcaagtattg gaggattgaa
     2641 aattcatgtg gatatatcag aaaactatac aacacccagt taatataaaa acttgtgacc
     2701 ctagaatggc taaatttctt ataactcaat ttggtgggcc aaatggagaa cttgctgcat
     2761 ctttaagata tttaagccaa agatatacaa tgcctactgg taatatgcgt gcacttttaa
     2821 cagatattgg tacagaagaa ctagctcacg ttgagcttat atgtactatg gtttatcagt
     2881 taacttctga tgcaagccca gaagagttaa aagctgcagg tcttggttca aactatgctc
     2941 aaaatggata tggaatttat ccaacagatt caaatggtgt tccatttgat gtaagaccta
     3001 tagcagttat gtcaaatccc gtaaccgatt tacatgagga tatggcagct gaacaaaaag
     3061 cacttgcaac ttattatcaa cttataaacc taacagatga cgttgatgtt atagatgtat
     3121 taaaattctt gggtcaaaga gaaataattc attatcaaag atttggtgaa gccttaatgg
     3181 atgcttacga gttagaagaa tctcaaaaaa tgttctaaaa tttttatttg tataactatt
     3241 attatttgat aatttataat ttactgttgt gttaaaattt ataaaaaata taaatataat
     3301 ttattttcta taaacagaga aaataaataa aaagcaggta tcaatcaaat agtaacatgt
     3361 attatactat acattactat caatattgta cctgctttca tattataagc aataaagaaa
     3421 aatctattta ttaggtttta taataaaaac aattataaaa ctcttcttgc atttacatat
     3481 ctacttgaat agtagctact atttatatta gatattgtta ctttttttga tgaacctgaa
     3541 gatgcatgta tcatatctcc atttcctatg tatattccaa catgacttac agaaccatta
     3601 tttgaacctt gtgtatcaaa gaatactaaa tctccacttc taaggtctcc tctatttaca
     3661 tatgttccat acttactttg gtctctagat actcttggta tactaactcc tacagatttt
     3721 ttcataacgt actgcgtgaa tccagaacag tcaaaactat ttggaccttc tgctccccat
     3781 acatatggtt ttccaagtag tgtctttgca aaacttatta cactatcagc tccttgactt
     3841 ggagaattag tcgaataaga tggaattgaa gtatcaacag aacctttttc agcaaggtat
     3901 tgacttgaca catatccagt ttgattgcca taacttattt ttgtccatcc tccactttca
     3961 gaaatacttc caacctcagt accataactt aatgtagcta ttttagaatg acttgtacct
     4021 ggtcctgttc taacgttcaa tgactttgct gttacaacct ttgtaccctt tacaaggtca
     4081 tttgaactgt tttcagcatt ttcatttgta gagtcattta cactagttcc taaatattta
     4141 cttgaaacat aacctactct accattagaa cttatttttg accatccatt tgactcagat
     4201 atgtatccga cttcagtccc atatcctagt gttgatattt tagaactact tgtacttggt
     4261 cctgttctaa aatttaatcc ttttgctgtt acaacttttg tcgacttaac tgaagtatca
     4321 ctactttcat tgctacttcc aaggctattt attgctacat aatttccatg cacataacct
     4381 gtgtttccat tatatttaac ttttacccaa gaaccttctt ttcctacgta ctcaacttta
     4441 tcacctttgt aaagtttccc cattgattca tggtttgtac ctggtccttt tctaaaattt
     4501 accgcattcc ctgttattgt tctgctttct atactcacac tctctacttc agactcatta
     4561 gcatatgcta aattccccat agtaggcatt attatcgcag ttgccattat actggctgct
     4621 attctctttt gattaaaatt cataactttc cactcatctc ctcttttcta ctatctttat
     4681 ttcacttcaa aatataaaag aaataattga cactatcaaa atatcaatta tttcttttat
     4741 attaatatta ttacaaattt gtaactattt gtctatagta atatttgctt accataaatt
     4801 accatgtata aattttaatc tttaatagcc tgtaatttag taatatagcc atcttttacc
     4861 ttttttaaaa atggctatat tttttaactt ttttgtaact ttttaaaatc cagttgagcc
     4921 aaacccacct tttcctcttt cggagtcact taattctttt acttcttcta tgttaatatc
     4981 atagataggt tttactatca tttgagcaat tttcatatgc ttttcaacct taaaatcatt
     5041 tttaccatga tttattaata taattttaag ctctcctctg tatccttcgt caatagttcc
     5101 tggtgtattt aatacagtaa cagaatgctt taaggcaagc ccacttctag gtcttacctg
     5161 cgcttctgtc atagtaggaa gctctataca tatcccagtt ttgataagtt tagtctctcc
     5221 aggaggtatt acaacctctt ctatagaata caaatccata ccagcatcac ctttgtgagc
     5281 aaaattaggt attatagcat catcatttaa tttttttact tttaaattgt acatcttata
     5341 tctcctttca actttctata aatattataa cttaaatttc gacctcttga agttttttat
     5401 ttttttgtgg taatataatt attagtgttt taaaggagga ttttttatga aacttgtact
     5461 tgctgagaaa ccatctgtgg caaaaactat agcatcattt ttaggtgcaa agaccagaca
     5521 agatggttac tttgaaggaa atgattatat aattacttat gcagttggac acttagtatc
     5581 attatatgat atgaaggatt atgataaaga taaatactct ggctcttgga aaatgaacaa
     5641 tttcccattt gttcctgagg ataagtttaa atttaagatt gatagttcta aaactaaaca
     5701 attcaacact gtaaaaaagc ttttgaatag aaaagatgta gaatatgtaa taaatgccac
     5761 tgataatgac cgagaaggag aacttatagc atttttaata tttttactgg caaaaaataa
     5821 aaaaccagta aaaagaatct tggtaaatga atggacacca gaagatatta caagaggtat
     5881 aaaaaaccta aaagatgaag atgaaatgag aaatcttcaa gctgctggat atactaggct
     5941 tattactgac tggttgattg gaataaattt cacttctgtt gctacattga aatacggaaa
     6001 tgggaaacta ttaaacatag gtagggtaat tcttccaaca gttaaattag tctatgatag
     6061 agatatggaa atactaaact ttgttcctaa aacttattat gaaatagaag ggcattttaa
     6121 agctgaagct ggtgaatata aaggtaaata tgttaagggt aaagaaagta aatttgatac
     6181 acttgaagat gcaaataaaa ttatagcttc aattacatct gaaactggta aaatactaga
     6241 taaaaaagtt actatgtcaa aggaatatgc accaaaactt tttagtttga catcacttca
     6301 aggatatata acttctaagt attccaattt tacatctgat aaggttttaa atgtctgtca
     6361 atctctctat gagggtaatg gtaagggtgg atacataact taccctagaa ctgattccat
     6421 tttcttagaa gaaagtttgg cttcaaaagc ttctcaaact ttagataaat taaaggttgg
     6481 tcttgaatat gaaaataaaa ttaaattttc taaaactaaa agagtttttg attcttctaa
     6541 agtagactcc catagtgcta taattccaac ttatataatt ccaaaaagtt tatctaagga
     6601 tgaacaatta gtttatgatg ccataaaaga tagatttgta gcaaacttta tgcctcctgc
     6661 tgaatatgag aatacagaaa ttaagactga agtagataat tgtactttct taacaaaagg
     6721 taaggtgctt aaatcaaaag gataccttga ggtatataat aaggaagaaa aaaacgattt
     6781 acttccactt gtaaataaag atgatgttgt agatgtgtta gaaataaaac cattaactaa
     6841 gcaaactact ccacctaaac cgtatactga ggacacactt ttaaaggcta tgaaaaattg
     6901 tggtaaaaat gtgcctgaag aagatacaac agtgctatct ggatattcga ttggaacatc
     6961 agccacacgt gctgatgtgt taaagaagat aagtcaagtg ggctatgtaa agaaaaaagg
     7021 taaatcttat tctataacag accttgggaa aaatttagtt gaaatttttc ctgttaaaga
     7081 cttatttgat gtagattata ctggaaaact tgaaaaaagt ttaagcgata ttcaaaaagg
     7141 aaagtataca agaaaagaat atcttactaa tatcattagt tttatatatc aaaatgtcaa
     7201 tattataaaa caagatgctt caaaaaatat aaacacagaa gcatatactt tcgattcaaa
     7261 aactaaaaaa tttactaaaa caaaagaaaa aaaacagaaa aaagatgtaa ctaatactga
     7321 aaaagaagtt gctatatcaa aggattctaa taacaaaaaa gaagttaaaa atggtgatga
     7381 aaatcaatct cttggcaaat gccccatttg tcaaggtgat gtactagaat ttgacaaagg
     7441 ctttgcttgt aaaaatcata aagaatgtaa atttgttatt tggaaaaatg ataagtattt
     7501 aagtctttat aaaaagaaag ttaacaaaac aatggtcaaa aatattttaa aaaaaggtga
     7561 aactaaagta aaatctttaa ctgctaaaaa cggtaataaa tttgatgcta cattaaaata
     7621 tgataaaaat ccagatactg gctatttcaa ttggaaaata gagtttgaca actaaatatt
     7681 cataagaaaa gaaatagcag tagtataata atctatatta tattactgct atttcttttc
     7741 ttatgaagtt tcaacttttt taatagtgac ttttacaatc acactctaac ctaatttctt
     7801 tactatttct gataacttta atgtatgttc atctaataaa gttagttcct cttcagaaag
     7861 attagataat ttttttacta gagattcttt gagaatagct tttactgcat caaataattt
     7921 aaatgcttta tctgttaatt caaccctaag aatccttcta tcttttgggt caggaaattt
     7981 attgactaaa ccatgttcca ctaatctgtc aataatcgga gtcatatttg attttaaaat
     8041 tcctaaatta gaagctattt gagaaattga tgatgaattt gatgtcataa gataaagaat
     8101 taccttagca tgtgatggag ccattggaca ttcttcaaaa taagctttca ttatatcaga
     8161 gttattttga aactttttta acaaatcgct ttctttaaat atattatttt caagcacaaa
     8221 taaaaaatct aaaaaagagt ccgctatttt aagtatattg ttgttatcca tatttgtaac
     8281 atcccttcaa tagataatat aataaaacat tgttgtttaa tatagtataa attataaact
     8341 attaataaat ttaaaacaag aaaaagttat tgactcataa taattataaa tttataatca
     8401 aattagagaa ttataaattg ccaataaagg gaagtttttt aattagtcta aaactaaact
     8461 taaattataa gacactttaa attctacaac aagctagtgt gcaatatata ataggaggag
     8521 atatgaaaag atatttaata gttttcttaa tgtgtagttc actgttttta gttggatgtg
     8581 gaaaaacaga agaatctgaa cctgagaaac caatagcagt ttctgttcaa aaagcaatag
     8641 gtggagaaat tgaaaacaca aattctttct caggaactac aaaggttaaa gatgaaacag
     8701 ctgttactgc acagactgtt ggcacagttc aagaagtgta tgtaaaactt gggcaaaatg
     8761 taagaaaagg agatgaatta ttgagtataa gcagtccaga gctagaaaat agtgtaaagc
     8821 aaagtaaagc ctcactagat ttagcaaaag caagttattc aagtgccact ggtggttcat
     8881 tagaggcaca agtaaatcag gcaaaaacag ctcttgacaa tgcaaagatt caatatgagg
     8941 agtctcaaag aaattatgac aataataaga ttctttatga acaggaagtc attagtttag
     9001 accaatttaa aaaaatagaa ttttctttag agcaaacaaa acaacagtta gattctgctc
     9061 aaagagcata cgatacagca acttcaaaaa gtatacctca agctaaagca cttgctaaaa
     9121 aacagcttga ccaagctcaa gtatcatata atttagcaat gagtaattta gacaaattaa
     9181 cattaacatc tccagtagat ggtacaataa cagctaaaaa ctttgattca aaggaaatga
     9241 taacacaatc acaaccagct tttattattt ctaatcctaa tatactagaa gttgatttaa
     9301 atgtagcaga atcagatata ggtaaattta agaaagatgg aaatgtagat gttataattg
     9361 aagaccaaag gattttagga aaaatagatt atgtaccttc agtagttgac cctcagacat
     9421 ctttatatcc tgttaaagta cttgtaaata atacaaacaa caaatttaag gcaggtatgt
     9481 ctgctcaagt aaacttaagt gttgaaaaag aaaatggtgc tgttacagta cctaaaaaag
     9541 caatatttga agaaaatggt aaaaaatatg tatacatagc aacaaaagac aatatagcaa
     9601 agaaacactt ggttcaaact ggaattgtaa cagaggataa aatagaaatt aaaagtggtg
     9661 taagtgataa agatacagtg attatcggag ggataagtct tatttctgac ggaactaaga
     9721 tatttcctgt agaaaaggag aagtagacta tgaatttaac acagacttcc gttaaacgtc
     9781 ctctcacaat cataatggtc tttttagtat taatagtttt tggtggtatt ggatataaaa
     9841 aaatgtcaat aaatctaatg cctgatatag aaataccagt tgtaatggtc atgactactt
     9901 ggacaggtgc tggtcctcaa gacgttgatg aacaagttag tcaaaaagtt gatgaaagtt
     9961 tatctgccgt ttcaaatgta aaatctacta tatcaagttc acaagaaagt gtttctatgg
    10021 tagttgctca gtttgaattt ggaactaatt tggatgaaat aatgaatgat gttaggtcta
    10081 aagttgatgc attacagacc agcctcccag atgatgcagc taaaccaaca gttttaaagc
    10141 tggatatgaa tgcacaggct ataggtcaac ttgtcatatc tggaggaaat gaaaatagtt
    10201 cacaagcctt aagaaaatac gctgaagatg taattcagcc taaaatagaa tccatagatg
    10261 gtgttacttc agcagacctt aaaggtggag aaaaagcaca ggttaatgta atagctgacc
    10321 cagctgttct ttcaaattat ggagttagtt tatccactat aaaaggtgtc ttatcctcta
    10381 gtaataaaac attcccttat ggttcaatta ctcaaggtga ggataaaata gttttaagag
    10441 cgattgataa attagaatcc ctagatgata taaaacagat tcaaattcct gtaaaaggag
    10501 gaaatacagt tagattagat aatctttgta gtgtagatta tggatatgca gacaaagata
    10561 gtatttatag atacaatgga aaagacagtt tggtaataga tatttctaaa caacaagatg
    10621 ccaacactgt aaaagttatg cagagtgcat acaaatacgt agatgaattg aataaggaaa
    10681 atcctcaatt taaaattaaa attgctaatg atacaagttc atacataagt gaatcaataa
    10741 acagtgtaat gagcaacttg cttataagtg ctgttatcgc atttattgta atatttgctt
    10801 tcctaaaaag tgtaagagct tcactagttg ttgcagttgc aataccaatt tctataatag
    10861 gtgctatagc aattctctac tttactggtg aaagtttaaa tcttattact gcaagttcat
    10921 tggtaatttc agttggtatg gttgttgata atgctacagt tgtaattgaa aatatattta
    10981 aatataggaa aagtggtaga ttgagtcttg atgattgtgc tattgaggga acaagaactg
    11041 taacaaatgc aatacttgca tcaacattga ccacaatagc aatattctta cctatcatgt
    11101 ttacagaagg tatagctaaa ataacttttg gggcattagg taaaacacta atagcttcac
    11161 tagcattctc ctttataggt gcaattacac tcgttcctag tgtatttgca aaattaagca
    11221 gaggaaaaaa tagtcaaaag atgcaagaaa aagatagtcc tatatttgat aaggtaagtg
    11281 aagcatataa aaaattatta agtgtatgtt tgagacatca acgcttagtt gtaatatcaa
    11341 gtttacttat ttttgtagct tccttatttg gaatgggatt tataggtatg gactttatgc
    11401 ctgcagcaga caagggtgaa ttatctattt ctatagaact tccaaaaggt cttagcctag
    11461 aatccaatga ttactatgta tctatgactg agaaaaaagt ctcagatatt ccagaaatta
    11521 aaactttaat aacaactttg acatcagatt caaataatag taaagcaagt atagcaattg
    11581 aattagaatc tcaaaaaaat agaaaaagaa ctactgatga aatagaaaaa gagataattg
    11641 atagagtggc tactgtacca gattgtaaaa taaatgtaag tcaaaacagt agtgttatgg
    11701 gtggagctgg aggagcagac ttcacattag aaatgaaagg tcctgattta gatgtattaa
    11761 aaatactggg aaaagaagct gaaaaagaat ttagctctat aaaaggattt agaaatgttg
    11821 aaacttctct tacagataca acacaagaag ctcaatttac tatagataaa cataaggctc
    11881 aagaatatgg tgtaaatacc gctgaaattg caggcatgtt acgtacagca ataaatggtg
    11941 actccgtaac cactgctact attgatgatt acaaagtgga tgtaaaccta aaatttaaag
    12001 cagatactat tgatagctta gaagatataa agcaactaaa agtaaactct gcaactggaa
    12061 aagaagttcc tcttggtgcc ttttcagata taaaaatggc agatggtcta caatctatat
    12121 ctaggactga tggagatttt tctgtaaata taactgctac acttgacaat ttagatgctg
    12181 gtactgctac aaaactagca ctagaaaaaa cgaataaaat ggtaattcct aaagattact
    12241 ctataggtgt tggtggtgaa acagaaatga tgaatgaatc tatggcaagt cttggatttt
    12301 caatggtcat agctatagca ttagtttata tggtaatggt agctcagttt gaatcattta
    12361 gtaaaccatt tataatcatg ttctgtgttc catttgcatt cgttggagtt gtgctttcgc
    12421 ttctagttag tggtcaaagt ttaagtactg tcggtatgct aggtataatc ttacttatcg
    12481 gtattgttgt taataatggt atagttctta ttgactacat agagcaactt agaaaaacaa
    12541 atcgtaacaa tgatttaatt ggtttggttt caattggttg tgcagcaaga ttaagaccag
    12601 tcttaatgac tacagcaaca acaattttag gtatgttgcc aacagcacta tctcttggtg
    12661 aaggtggaga aactatgcaa ccactagcca tagttataat gggtggtcta actgtatcta
    12721 cacttataac tttggtgctt atacctacta tatacttaat atttgataaa tgggaaaata
    12781 agttttcaga caaaatgcct aaaatatttg gtaagataac agataaaata ggaagtataa
    12841 aacgtaaaat aataaagaaa ccaaaattga aagctaaagt ttaaatagaa tggagggtga
    12901 ttgtattgaa taaaaaaatg agcaaaatag ttgcaattag ctgtggtgtt ggtataataa
    12961 ctgccaattt aatcccagtt tacgcagata ataatacttc ttctataaac aaagttgata
    13021 attctatttt aagtgactca aataaaagaa catctgaaaa ggaaattttg actgctagag
    13081 aagctgttag tgctgcactt aaaaatagtg aaaaattaaa aatgaaatca gaagaaataa
    13141 aaatgttaaa agaaaagtta gaagtacaag atgagtttga tagttttact ggaagtgaca
    13201 actcgtttcc atacgaccaa attggacttc ttaaaaatca aagtgaacag gctaaaggct
    13261 ttatggagga ccaaatagca aatgatatta ctaataaatt taacgattta gtttcaagag
    13321 aaaatgagct agataaaata aaaaacaatc ttgaaataaa aactaaagaa attaaagata
    13381 tgaaattaaa aaaagattta gggttagtaa catctttaga aactgaatca gctgaacttg
    13441 aacttcaaac actacaaaat actcaaaaag ctaaacttca agaactaaaa aacaatcaag
    13501 actattttaa gttattaact aatatagatt taaataatta tcaattggat aaagaatata
    13561 gatttgaatc ttttagagta ggtggctcag ttgattcata tatggaaggt aaggttaatg
    13621 aatatttaaa atacgaccaa ttgattttag aacgtacaga agaaagcttt aatgataaag
    13681 atgagaacaa agcagattta ccagatagac ctaaccttac aagaccagtt gctcctacaa
    13741 aaccagagca aggtaaccta actgatgatg aatacaaggt tcttatggat aagtatgaaa
    13801 aagattatga tagatataaa aaagaagttg aagcatacaa tcttgaaaga cagacttatg
    13861 ctgctggcct tactacttat gcaaattatc ttcaacaaaa atttaatact gaaaatggtc
    13921 tagtaacatt agaagacagt aaaaaagctc ttaaaaaagg gttaattgat agctatgctc
    13981 aattacttgc tttagaagat acaattcaga ttactaaaaa acaacttgat ttatcagaaa
    14041 aacaattaaa aaatactaaa ttaagatatg atttaggatt aattactcta actgattata
    14101 aaaaacaagt ggtaagtaat gaagatgcta aaaatagcta tgacactctt attgtgaatt
    14161 ataactcact aaaaaatggt atagaaaaac cttggatact taatactgga aaataattct
    14221 ggtaaataga aagattactt taacatacgt ttgattaaaa aatagttatg catactcgtg
    14281 gctttagtca tggaagattc agaaggcaaa taatagaaat agattagtaa aaatatattt
    14341 acttataaaa ctgtatactt ttatagaggc tatctcaaaa tagagataag cctctttttt
    14401 attgtttaaa ttataaaaat atatttgatt ccatacaaaa agagtgcctt ctgaactaaa
    14461 aagttcattt tgagacaccc tcaaaagctt aactctaaat ttaattattt tttatcaaat
    14521 gtttcatcta ttttacatct caccatgtta acaaattcag aaatattata tcctctaagt
    14581 ttgcatccac atttaggaca ataatccagt ttcctagata ccaaagccct acaactaggt
    14641 tctggacatc ttatttttag actctcatct gctactttaa atccacatcg tgggcatata
    14701 ctacctggac gtgatgatac ttcctttcca catttaggac actttgtcaa ctttatcccc
    14761 tccagtaaac tcaatttaat tgatagttga aatttctctc tacaataata tatgcaatat
    14821 aattaaatac gtttcactta caactatata agttaaattt ttataataaa aatcccctat
    14881 attcaattta caaatactta atttgataca ttgaacaata ggggatttta tttttattta
    14941 gttacatatt ttgcagtcta ttattatcta ggatttttta tagatgcttg agctgctgca
    15001 agtctagcaa ttggcactct aaatggtgaa caagatacat agttaagtcc tacactataa
    15061 cagaactcta ctgaagatgg ttctcctcca tgctctccac atattcctag ttttaattct
    15121 ggtttaactt ctctacctaa tttagctccc atcttaacta acttaccaac accattttgg
    15181 tctagtactt ggaatgggtc tttttctaat atttcttcat ctacatattg acctaagaat
    15241 ttaccagcat catctcttga atatccaaat gccatttgag ttaagtcatt agtaccaaaa
    15301 ctgaagaagt ctgcttcttg tgctatttca tcagcagtta aacaagctct aggtatttct
    15361 atcatagtac ctacagtata aggaacttct ataccttctt cttttattat agcgtcaaca
    15421 gtttctacta tcatttttct tattattttt aactcattta cttctccaac taatggaacc
    15481 attatctctg gagaaacttt aacacctgct ttgattgctt ctatagcacc ttgtattata
    15541 gctttagatt gcattacaca tatttcagga taagttattg caagtctaca acctctgtgt
    15601 ccaagcattg ggttaaactc atctaaatca actattctct tcttaatatc acttactttt
    15661 attcccatag attttgaaag ttcttctata gtctcatcat catgaggcaa aaattcatgt
    15721 agtggtgggt ctagtaatct tatattaact ggttttccat ccataacttt aaataactct
    15781 acaaaatcct ctctttgcat tggtaatatt ttttcaagag ctttttctct ttgttctact
    15841 gtattagata atatcatttc tctaactgct ggcaatctag cttcatcaaa gaacatatgc
    15901 tcagttctac atagacctat accttctgca ccaaactcta tagctgcacg agcatctcta
    15961 ggattatctg cattagttct aaccatcata catttgtgtt tgtctaccca gttcattaat
    16021 ttttcaaaat ttccagttaa agatacttct gttttcttaa catctcctag gtacacattt
    16081 cctgtagaac catctataga aatgtattct ccttctttta taactacatc atcaagtgct
    16141 cttatttctt tattaaactc atcaactttt atttctccac atccagcaac acaacattta
    16201 cccatacctc tagcaacaac tgctgcatgt gacgtcattc cacctctagc tgtaaggatt
    16261 ccttctgctt taaccattcc ttctatatct tctggagatg tctctagtct aactaaaact
    16321 actttttctc ctttttcatt tgcttttact acatcatcag cattgaaata aactttacca
    16381 cttgctgcac ctggtgatgc tggtaaacct tttgctataa ccttggcttc ttttaatgcc
    16441 ttatcttcaa attttggatg taataattgg tctaattgat taggctcaat tctcatgata
    16501 gcctcttttt catcaattat tccagcttca actaaatcaa ccgctacatt tattgctgct
    16561 gctgctgttc tcttaccatt tctagtttgt agtatatata atctttcatt ttctatagta
    16621 aactctatat cttgcatatc tttataatga ccttcaagta tatgagtaat ttttacaaat
    16681 tcatcgaata cagctggcat tacatctgca agagttgata tattttgagg agttcttata
    16741 cctgcaacaa cgtcttcacc ttgtgcattc attaaaaatt caccaaataa tttattttct
    16801 cctgtagctg gatttctagt aaatgcaaca cctgtaccac tagtttctcc catattacca
    16861 aataccattg attgaatatt tactgctgtt cctaagttat gagctatatc attcaattta
    16921 cggtatacga ttgcacgagg attattccat gatctaaata cagcctctat tgcaagcatt
    16981 aattgctctt ttgggtcttg tgggaaatca ttttttattt cttttttata aattgcttta
    17041 aattctttta ctatttcttt taaatcatca gttgtaagtt ctgtatcaac tgtgtatccc
    17101 tttgcttctt ttactctgtc taatacattt tcaaatttat attttggaac ttccatagca
    17161 acatcagaaa acatttgtat gaatcttctg taactatcat atgcaaatct ttcattttgt
    17221 gtagcctctg ctaagccaac aacactattg tcattaagac ctaggttaag aattgtatcc
    17281 atcattcctg gcatagagaa tactgcacca gaacgaactg atactaataa tggattctta
    17341 ttgcatccta atgttttatt taagtctttt tctaaagtag ctaaatgctc ttctatttct
    17401 tttattatct ctgctcttat actttcattg ttaacataat aatcattaca tgcttctgtt
    17461 gttatagtga atccaggagg gacaggtaag cctatcttag tcatttctgc taaattggca
    17521 cctttacctc ctagtaaaga tttcatgtct ttgcttcctt caccaaaact ataaacatac
    17581 ttagtttcca ttgttaaatc ccccattaat ctttttattt taatttatat catttttatt
    17641 aatagacatt attaaatttc tatttctttg tatatcttta gaccattttc tttcattatg
    17701 tctaaaatta tacctgctgt ttcttctatt gccttatttg aaacgtttat tactgggcat
    17761 ccaattcttt tcattatctc ttctgaataa tctaactcct gaagtattct ttctaaatta
    17821 gcgtagtttg ctttactgga caatcctaaa gcttttaatc tttgggttct tatctcattc
    17881 agcttttcag gtgaattagt aagacctatt atttttttag tatctatctc aaacacttct
    17941 ttaggaattg gtatttctgg aactaatgga acattagcta cttttatatt tttattagct
    18001 aaatacatac tcaaaggagt tttagatgtt cttgatattc ccactaaaat tatgtctgct
    18061 tgaagaacac ctctagggtc ttttccatca tcatatttca ctgcaaattc tatagcttca
    18121 actctcttaa agtaagattc atctaatttt ctaattatac cagcttctct tttaggtttt
    18181 cttcctgttc tcttgcttat ttctcttagt atatctgtca ttaaatctat acaactaaga
    18241 ccttctcttt cgcaatatct ttcaacaata ctgcataatt cttcatcaac taatgtatat
    18301 acaattaaag cgttttcagc ttttgcattc tccaaagttt caagtagtac tcctttatta
    18361 atcatgtatg gaaatctttt tatttcataa gtttcattca cataaaactg agacatacat
    18421 gcctttgcaa cttgttgtgc agtctcccct actgaatctg atactgcata tataattagg
    18481 tttttcacca gcatacctcc ttaattgtca actatttcta agaatagctt agttatgttg
    18541 gtttttgata ttctcccaac aactctcata tgatttttgt cttctccctt atattcaaca
    18601 atcggaatcg aatctacttc atgttctatt atttttcttg aagctaataa aacacttgct
    18661 cctttagtta aagtgactac atttggagtt cttgtcatta tcatacctat tggcatttta
    18721 tttatatcag aacctcctat agttgctttt agcaagtctt ttctggaaac aactccacat
    18781 aactcttcat tctcatctat aataactata ctccctacat cagataaaaa catagtgact
    18841 attacatcat atatactttc atccttctta gctagtacag gcatgctcat tatatcctct
    18901 actgtttttt cttttacact tttaccaatt aaatttattt cactaactcc tgaataaaaa
    18961 tatccaactt ttggtcttgc gtctaatatt cctgtcattg ttaatatagc taaatcagat
    19021 ctaagtgtag cacgagtcac attcaagctg gaggcaatac tttcactcgt tattggttca
    19081 ttttccttaa ctatatctat aatttttagt tgtctttcat taagctgaat aataatcacc
    19141 ttctttcatt gtgctatact ttttatcttt tcgcatctta tatagtatat tatataacta
    19201 tatataccat tctgtaaaca gattttttat tgaatacgat atatttttta ctaagttctc
    19261 tcgcttaaag atatttatta tatattaatg ggggatattt ctttaattaa tagaactata
    19321 ttagtattac agttaatatt ataatacata attggtcatt ttaattcatt ttatattaaa
    19381 atttttaata atattatttc aatgtgaata taaaattgca gaactaattc aaaataattt
    19441 ttacgactac aaataaccta taatatactt ttaaagaaag tatcctaaca agaatatata
    19501 aaaatttaaa agggttgatt taaaaataac catcaaccct ttttactaat atctatttat
    19561 attaccatca aatcttaccc aaatattttt tcttgcaatt gtcttaaatg atataaagta
    19621 gtatcttttt ctatctctac catatcgtaa gttataactt cacctttttt aatatctttt
    19681 acaactttag tctttttact tatcaaacca ataggtacag cattcatagc ctttgctaca
    19741 tcgtattttt ctatagtacc atagcatgta tatgctccat agccatccat aaactcacct
    19801 tttttcaaat ctttcttagc tatagtcata acttctgcta ctagtccagc tttaggtact
    19861 attgtagcct tatggtctaa gactgccata gctgctgata aaggagtctc taaactacat
    19921 aaatgatatg gtctatataa tatgtaatta ggtccatcac ccatacttaa atattttagt
    19981 tcatcattaa ctgcttttaa tttatgggct actactacga aaactccagg tgctatacca
    20041 tttacaaaat caactacacc ataattatct aatactccac cttcgctttt taatgcatat
    20101 ttcttaggta cttcattaac tgtagcttca ataccatgac cacctcttac atcaggcaca
    20161 aatccagttg cattacacat taaagccatt tctaccattg ttttagttcc ttctttaaaa
    20221 gaagctatca tatgaggtga agctcctttt ctttctgctt cttctctaac tgtatcagga
    20281 ttacaatcta aatctaattt attattttta cctttaccta tcactctaac ttcaaacccc
    20341 attgcatctg caaaatcaaa taattccatt actgcacctg gctcatctcc tgcagaacct
    20401 gtaaatatta ctccagcatc atctgctaat tttttaagta ttggtccaac aacacaatca
    20461 gtttcagcat ttaacataac tatatgtttt ttatttaaaa tagagtttaa tgctatctct
    20521 gcaccaattg caatacctcc agttgcatct ataactacat ctattgactt agttttacaa
    20581 gccacaagaa aatcattaca tgtcaatact tttccttctt gtaattttat ttctgcatcc
    20641 ttttcatttg ttacattatc tataatttct tcatctattc ctgcatcagt aaaagcttta
    20701 tgagccaact ccaaatttat atctacaaca atagaagctt caataccttt catatttgcc
    20761 atttggctta ccattccatt tcccatatgc ccagctccta taagagctac ttttattttt
    20821 ttaccttcct cttccaattt tgcaagtttt ctgtttaaat ctaacatacc aattcctcct
    20881 gttataataa ttttattttc aaattaagaa atagttatta aatctccaat agttatatct
    20941 ggatttccta tttccacatg tatttctcct ggtaaattta cttcacattt tccatcaaat
    21001 ttgattgtac aatgcccaat ttctctaaga gtcttctgag caatatcacc aactgaaact
    21061 atacaataat ctctattccc tatagtaagt gtatctccta tttcaacatc actttttaac
    21121 gttgctattg aatgaattac agatatatcc tttaagtcgt catcattaat ggtttcatca
    21181 tatataataa gacaattgct ttcatccatt aactctttaa ctaaactgcc tatcccactt
    21241 atcttaactt catatttcat gacattcctc ctgataattt atatttatat tgagttaatt
    21301 aaaagaaaca tttatttttt cttttataaa ttttatagct tgtacaatac tctcttcatc
    21361 tttaaatttt tgctctgcac tatatatatc taatccttct atttcttcaa tctctttaaa
    21421 tttagccatt actgtacgtc cttttaaaat ttctccaaac tttataaacc catctgaatc
    21481 tgaagatata atggctatac ttcctttaga aaaatagctt ttctttttgc ctgtagacac
    21541 tatatcaccc ttttttttag ctctatttaa agttttaaaa tacaatttat tctgcttcat
    21601 tataaatata gtatttaaaa tataagcaac aaataaaatc actaataatt tcatatttat
    21661 acaccttcca aaaatcacat tatttttaaa tctgtataac aactataaat gctgtacaat
    21721 agttatataa ggtttttaag taacaccttt ttaaattcta aaaaagttct acatttactt
    21781 atcttattcg ttaattttac atcttggcct atctttaaaa cttcttcata aatttttact
    21841 aataagtctg agtctatctt attctcacat ggaaacattg tcataagaat tatttttata
    21901 cttctatttg catattctat tggttcttct aaaattccaa ctgccattaa aaacttatct
    21961 gatttttcat ttacagaatg aggaaataat aaacctttat caaatactgt gggagatttt
    22021 tcttctctat tgactatatt ttttctaaac ttatcatcaa tgcatcctaa atccataaga
    22081 tggtccatca ttttttctaa tgaagcaagt atagtctttt catttaatat cataaattta
    22141 tcttcatcta acaaattatt tattagtaaa tttgtagaat tagtagtgtc aatattccct
    22201 tctcttaggc acaatactgt ttttaattgt tctcttagtt tgttttcatc aaatattgta
    22261 tttattttta atactattgt atttatattt gatgtgtcta aatcaatagt tgtaaaaact
    22321 atatcatatt catctaagtt aatatttctc aaattaaaac ttgaaagagt atcaatttta
    22381 ggattatttc ctatcagttt ttctactctt attttcaata gttttgctgt tcctagacct
    22441 gtactacata taattgctat tttttttatt gaatagaatc tactgctatt tctttctaaa
    22501 tatccactga aatggattgc tatatatcca atctcatctt ctgaaacttc taagttatac
    22561 tttttctcta ttacttttcc tgctatttgt gctaatttaa atggaagtat ataattttgc
    22621 ttaatctctt ctaacaaaac attttttaac tttatattaa ataatagcct gtttaaagta
    22681 aaactaagat gatatcctag acctactctt aattcatcct catttataaa aatacccata
    22741 tcgacatata tttgattaaa tatattttcc atcaactcat caatgttttt actaattcta
    22801 ctactattta aagcacattc tgatgctggt gcatttccac taactaacgg tatagttaaa
    22861 taaataattt cttcatcatt taaagtacat tcaaacattc ctgatattat atgttttatt
    22921 tccctagcaa taaagtattc atcatatgat ttaagtaaat caaactttac atcataatct
    22981 tttactttct tttcttcttt tactctatag actaaaacta ctatgtagtt aataacttct
    23041 cttaacattt catctgtaac ataaaaatta ttttttttaa ataaagtcaa tagtttttct
    23101 tctaaattta tgatttcttc ttttttgatt cctttaaaat actttgaatt actgaaatct
    23161 ttccttgagt ttttatacaa ctgatttaat ataaacagtc taatatcaag ttcatttcca
    23221 tttaatttca tacctgtatt ctgtttttta atcaagttta aattatatga agccaaaact
    23281 ttttctacat actggaaatc atttactaaa gtagttcttc ctacacacat ctcatcagct
    23341 aaactatcaa gtgtaataaa tccatctagt tctatcaagt aatttagtat aaactctact
    23401 ctatcttctt ttgaatttaa tgaaaataca ttttttctat tcatatcaat aatcttattg
    23461 agtatctgct catcttttat ttctagttta tagccttgac cctttatata tttgattact
    23521 gctatatcat tacctaaatc tttattcaat tgttttatat acgtccttac acttctagtt
    23581 gtgacattca attcatttgc tattgagtta atactcacaa actctttttt actacacata
    23641 atcaatatct taaatatctt gcggtcaata gaaggaattt tctcagttac actcattttg
    23701 tatctcctcc ttgatttcat tctagtacaa atttgaaacc aaattaatac ataaaatttc
    23761 actttaataa aggaaaattt agtattaatc taactcgata attacagcta attaatagta
    23821 taaaagctag tctttcatta acaaaaaatc ttgactagct taaatttata tttacaattt
    23881 tattaattaa ttccaagcct tatattgaca ttaaatatta tctcaatgca aatactgcaa
    23941 ctccatatgc aataataaca gctattggac cagttattaa acgagagtaa aataaagctg
    24001 gaacaccata ctctacagtt tctggttctg cttctcccaa acttaatcct actggtacaa
    24061 aatcacatcc agcttgccca tttattgcaa ataaagctgg aagtgctaaa tatgctggta
    24121 ttgcaccaag accaatttgt gtacctacaa gagtccctac tacttgagct ataactgcac
    24181 caggtcctag tattggtgat aagaatggaa gtgtgcaaat tactgatata atcaataatc
    24241 caccaatatt acctgcaagt ggagatataa ctcttgcaat ccagtctccc agtccagatg
    24301 ctaaaataat tcccataagc atacttacaa atgccataaa tggtattacg ttattcatta
    24361 ccatttggat agtatctcga cctgcatcat aaaattttga tactacttgc cctgcccctt
    24421 gaccaataga aagtattatg ttctttttag catattcacc ttgtgctttt gacttaacct
    24481 catcataatt atcaggcttt ctaatagaac tcttattttc gcttttattt tcttgagatt
    24541 tttgtggcat atcttcccca tctacaacac ttatacagtt aggattaaca tctgatacat
    24601 aatattcttc tgttataaat tttgctaaag gacctgtttt tccaactgga tttacattta
    24661 ttgtaggtat ttttttcttt ggataaactc cacatctagc agttccacca caatcaataa
    24721 taactactgc tacttcttca tcagaaactc cagttttaaa tccatctaca atttcacaac
    24781 ccagtagttc ttttattttt aatgttactt catggatacc accagcagtc attgacagta
    24841 tcttatttct attcccttct ttttttatat acaaaggacc tccccagcct gaagttccct
    24901 tttctatttt taatatttta ttctcctcca ttttatctac ctcctaagcc ttatttgttg
    24961 ctctattttt tcttgttaga aaagcataca ttttttctgt tactatacct cttataaaaa
    25021 ttacaattag accaactata aaataccaca atgccaatgt agtagtttct ttacctaaag
    25081 tagtcaaacc tgcagatatt cccaaccata caaaaagttc tcctgcattt gcatgtggaa
    25141 aaagacctgt aattggatgt acaaatgaaa ctgctgcatc ataaaatcct gctttgtgct
    25201 cttcttttaa aaatctacca aatgtatagc acataggatt tcccaagaaa aatactgata
    25261 ctaatggaag tagaatatat cttgtaaaag agttctttcc tagcttagaa gcccaattat
    25321 taactctttc ctcaccaatt atcttaatca aagagttaat agctaccatt aatacaatta
    25381 gcgttggaag agtacctgaa acaagaccta taaattgttc tccccctttc tgaaacaaac
    25441 cgataaacca ctctgcacct ttacttagac ctgtaataac gttttccata aaattataac
    25501 ctccctataa tatctttaaa tttttaattt tactgcttac cataaatttt acaaattaca
    25561 tcttttttct gtactatatg ctaatattgt aaatgttttt ttattaatat cattttaata
    25621 taatattttt gataaataaa tacatctttt ttcaatttta taaaggaaaa aattgtacta
    25681 attagaattt tcagaaatat acaattctta tttcgactat attctaaatt cttcttagaa
    25741 atttaagaac ttatttttat ttcttttatt attaaaatta tctaaatctg ataaaaataa
    25801 aaaatagatg ctcttttacg aacatctatt tcttaatcaa attatttttt agttttctta
    25861 tagattattt tataggtata taaatatcaa tttgtgagtt cacattacta ggacctaaaa
    25921 atcgttcatc atatacttca aaatcatctc ttatatcaag ttcttctttt gaacttaaaa
    25981 accaagtacc ccatatatat tcataagttt tgtctaaatt atctaagcta ccagtatgag
    26041 taaatatagc atactttcct tccttaatag tttttgaaac aaatgaattt ggaatcacat
    26101 cataactatt aacttcaagt cctattatct cattaaattc catactttca ctaactaggt
    26161 gtatttcaga gattgcttca cagattccaa aaactctctt tgatggcaaa gtatttggga
    26221 caatatgatg tacttttctg aatttctccc acaagtcagg taatgaatta ttttctaaaa
    26281 ttactttatc ctttatacct attaccttta ttttttctat ttcttttata actggtttaa
    26341 tcgttatatt tccaacaaga tgtctcataa aatctaactc taattttttc tttttaccaa
    26401 caaatacatc aattctattt tttctatatt ctatagggct aaccttgtat atagatttaa
    26461 atgctctgct aaatgcttcc gaagattcaa atccactacc aatagctata tctatcactt
    26521 ttttatcact atataaaagt tcttttgtac tacttactaa tcgtcttttt tttatataac
    26581 ttcctacact ctcaccaaac atagacttaa ataagcgtgt taaatgataa taagaatatc
    26641 cagtttcttt tgccacatca tttacagtta tattttcatg taaattattc tcaatataca
    26701 ttacagcttt tttaaaatac tttaagtaat ccaatatggc acctctcttc tacttaaact
    26761 ctttaaatat gtaaaatagc actatttttt actatactaa aatattataa ctaattcaat
    26821 acgataaata aaaactttta gttgatttat atatcctaat tatttagaat aattaaatac
    26881 attttttatt caatgaaatc aaaaaagtca gatggtgctt tttcaatatt tatgtttatc
    26941 ctctgtgtta tagatttaat gtcatttttt aaatagtagc tctcccattt attctctagt
    27001 ccaccccata aaatattaaa ctttcctata tttaaatcca taactatact ttttaaagtt
    27061 ccaaaaaaat cattatagta attacaagat aagccatttg gatattttga agacaataaa
    27121 ttcattaact ctttctctcc aattttttta gacttattta tatattcttt aattaattta
    27181 tatctatgaa tagaattttt cattgattgt ggctctaatt tatgaagttt atcaatatgt
    27241 gtatgattag tagagtgtaa aaaatattct cttttacttt ctaaactatt gattatattt
    27301 acttcttttt tcccatctaa agtctccaca agtgcaatgt ttccagactt atctgcaagc
    27361 aataaattaa tattgtatgc aattggcata tcttttaaat attctaatgc ttcatctaca
    27421 tctttgcaat tttctaacaa atatctaata acagcccaaa actgtaaacc tacaattgct
    27481 ggttttctta aaccatctga attgcctaca ggaataccac atgatgactg acttacacct
    27541 aagccacatt cattcatacc ttcacctctt ccaaattgca taacggtagt acctatatgt
    27601 gcatattttc catttacctt agttttacat aaaacaaaat cctccatatt gtgtgagaaa
    27661 tcgaaattac gtgcaaatag tacatgccca ttttcagtta attctggtgc taatgcaact
    27721 tgactacaac ctggtttaag ataagtcata gtataatata aaatttgatt acaattcact
    27781 tgaattgcat cagcaaaacc ttgcaattct tcattaagac ctggacaata tttatcaaac
    27841 aactctatca tctctttttc ttcttttttg cttaccagat tagatttatt aatctgacct
    27901 tctattatct ctggcatatt agcaaccaat tctcctagtc tgtatcctat ctcataattt
    27961 gtaccactca attcaatatt tcttacttct aaagtttcca tatgtacccc tcctatatat
    28021 cttataatcg attttatcat tcgaattgta atcattcatg atattttgtg ctacaagtta
    28081 aaaaaggtca tataaaaaca gataagcctc tttttcattg ttaaaataat aaaaatatat
    28141 ttaatttcat acaaaaaaga gtgtctcata aactaaaaag ttcattttga gacactcttc
    28201 ttattttaaa gagtataatt aaaaatagtc taagttctac tcttccttca tttttttcaa
    28261 taactctgga ttttcaaata aattaaatcc tgttaaagct aatattttta taccatcaat
    28321 tactctatct tttgcatatg aatttataga agcctccaaa aattcttttg tatgtagttc
    28381 ttctccattt tcagaaaact tcatcaaagg atgtatacat ggcattattt gacttaaatt
    28441 tcccatatct gttgaaccta acattacttg ttcatcttca tatattccaa attcctccat
    28501 aatctttgta aatatgtcta ccaaaacttt attttcattt aatccttggc aagttggttc
    28561 aaagtgataa aattcaagtt cacatccagt ggctattgca gcacctctag cacaattttt
    28621 cactttttct actacttcat caaagtaatt ttgttctttt gcccttatct ctaatcttac
    28681 ttttcccata tcaggtatta catttgcagc agttcctgct tctagtataa taccatgtat
    28741 tctcgttcca tctactaatt gttgtcttag tgcatttata ttattatata gtaatactac
    28801 tgcatctaaa gcatttattc cgttatatgg cttagctcct gcatgagatg cttttccagt
    28861 aaatatgaaa tctagacctc ctattgctat aatttcaggt gttacacaag tttttgaatt
    28921 tggatgtatc atcattgctg catcatagcc atcaaataca ccatgttcta tcaagtaagg
    28981 ctttccatct ccagtttctt cagcaggtgt tccaattata cttacttctc ccttgtaagt
    29041 atccagtata cttgaaagag ctattccagc tccaactccc atagatgcaa ttaaatgatg
    29101 tccacatgca tgtccattgc ctggaagagc atcatattct gctataaatg ctattttagg
    29161 accatctcca tttttcttgg ttgctttaaa agctgtagcc atacctgcca agttttcctc
    29221 aacatcaaaa ccctcttctc ttaaaaattc tgatattttt ttagcagatt tatattcttg
    29281 caaagcaatt tctggttcat catataaaga ttgacatagc cctagaattt tttctttctt
    29341 tgaatcagcc acttgtatta ttctttcttt cataccaatc ttacctccca ctaaatttat
    29401 ttagtaattt ttatatttta ttataacttt aatttaactc atgcttatcc tcttttaagt
    29461 atctattttc ccaaaactca gcatttctta tatctaactc tatagggtta aaagttctat
    29521 cactcctttt tattcccatc ttcttctgtc ttatataatc ataatatgcc tttatagctg
    29581 gtttttttag tgtaaagatg gcaattaaat ttatatatgt taatacacct atacatatat
    29641 cacctaatgc ccagcttgta agtggttcta taaaacaaca cattgctgca catgctataa
    29701 gcataaatct acagacatta attatgtact tttcatgttt ttctgcttta attctagtta
    29761 ctaagtaaga tacattagtc tccatcatat atgagaaggc taataaagtt gtaaatgtaa
    29821 ataataataa aactattgct ataaaaatat cacctaattg tggatgtaat gtatttattg
    29881 cactctgtac atattgtggt cccggttcta cacctggcag tgctgtgcaa acacctgtaa
    29941 cattatacat tcctgttatt acaatcataa tacctgtagc catacatatt aataatgtgt
    30001 ctacataaac agaaaatgct tgaactaatc cttgtttggc tggatgactc acttctgctg
    30061 ctgccgcacc ataagtccca gaaccttctc ctgcttcatt tgagtatata cctcttttta
    30121 ctccccaaga tattgctgaa cctagcattc ctccaaaaac tgaaccaaat ccaaatgcag
    30181 atttaaacat tgttacaata gcctctggaa ctaaactaat atttgttata attattacta
    30241 atgtcataat aaggtatgct ccacccatta taggtactac tttttcagca aataaaccaa
    30301 tccttttaat tcctccaaaa attattatcg ctaatgcaat agaagatgct actgctattg
    30361 tcatttttga aaatccaaat gcttgattca ttgctagata taaagtgttt gattgtgtac
    30421 caggcataaa aaatgtataa cttattattg caactattga aaataaaact gaacactttt
    30481 tccacccaag acctttttca aaataatatg gaggtcctcc tctatactgc ccatcatgct
    30541 catctttata tatttgagct agagtagatt ctacaaatgc agttgctgaa cctaatgtag
    30601 ccattataca catccatact aatgctcctg gacctcccat tgctattgct acagctacac
    30661 cagctatatt tccagtccct attcttccag ccatagatgt agcaaaacct tgaaatgatg
    30721 atataccaac atgagaacta tctccttcaa gcaagagagt aaacatttct tttacatctc
    30781 ttatttgaaa aaattttaat ttcaatgaaa aatataatcc tatacacaaa cacattgcaa
    30841 ctaatacggg tgaccaaaca attccattaa tggtgttaac taaatcggtc acttaactca
    30901 ccaccattca ttttatattt atagacaata atttaaacag ctatatttca atattttata
    30961 taatctttat attaatatat ctaaaaaa
//
LOCUS       DAGQVA010000048        29594 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.048, whole genome shotgun sequence.
ACCESSION   DAGQVA010000048 DAGQVA010000000
VERSION     DAGQVA010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29594
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.048"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            140..1054
                     /gene="murB"
                     /locus_tag="MIV85_002366"
     CDS             140..1054
                     /gene="murB"
                     /locus_tag="MIV85_002366"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBY2961698.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            1058..1771
                     /locus_tag="MIV85_002367"
     CDS             1058..1771
                     /locus_tag="MIV85_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBY2961699.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            1802..2659
                     /gene="rapZ"
                     /locus_tag="MIV85_002368"
     CDS             1802..2659
                     /gene="rapZ"
                     /locus_tag="MIV85_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBY2961700.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            2671..3777
                     /locus_tag="MIV85_002369"
     CDS             2671..3777
                     /locus_tag="MIV85_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBY2961701.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            3846..4271
                     /locus_tag="MIV85_002370"
     CDS             3846..4271
                     /locus_tag="MIV85_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBY2961702.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            4288..5235
                     /gene="whiA"
                     /locus_tag="MIV85_002371"
     CDS             4288..5235
                     /gene="whiA"
                     /locus_tag="MIV85_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBY2961703.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            5392..8961
                     /locus_tag="MIV85_002372"
     CDS             5392..8961
                     /locus_tag="MIV85_002372"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBY2961704.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            9170..10129
                     /gene="pfkA"
                     /locus_tag="MIV85_002373"
     CDS             9170..10129
                     /gene="pfkA"
                     /locus_tag="MIV85_002373"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBY2961705.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            10181..11941
                     /gene="pyk"
                     /locus_tag="MIV85_002374"
     CDS             10181..11941
                     /gene="pyk"
                     /locus_tag="MIV85_002374"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBY2961706.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            12116..13480
                     /gene="rlmD"
                     /locus_tag="MIV85_002375"
     CDS             12116..13480
                     /gene="rlmD"
                     /locus_tag="MIV85_002375"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBY2961707.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHIETCVLLQ
                     RRTM"
     gene            13723..16767
                     /locus_tag="MIV85_002376"
     CDS             13723..16767
                     /locus_tag="MIV85_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBY2961708.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPSTAVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDKNGNTDVVEVKAGTVYIRELSAPAGYKVDTT
                     VYSLKVEAGKTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAILPL
                     GTLSVEETKAPNGYLLDGAYMQAGDKSEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETSDTKPQGSATLKDTAFDVISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSAEWTSHK
                     HNTNAGKTSEDGVWFGTSEADDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDSEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFIADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKEIEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKAEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFNEKPEVPEKLETPQTPEKPN
                     RPSDSPKTGDSTNVMAFLVMLLTSAGGLAGTYLYKRRTMKKS"
     gene            16893..17219
                     /locus_tag="MIV85_002377"
     CDS             16893..17219
                     /locus_tag="MIV85_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBY2961709.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRKVIARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDVGHTDYVLVADDI
                     VAVEEK"
     gene            17235..17618
                     /locus_tag="MIV85_002378"
     CDS             17235..17618
                     /locus_tag="MIV85_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBY2961710.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNTGTSQNHTPQGQPKK"
     gene            17720..18157
                     /locus_tag="MIV85_002379"
     CDS             17720..18157
                     /locus_tag="MIV85_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961711.1"
                     /translation="MCEECYSDENRITPLLNPLDCLENHTQYICGTCGRCICIEHDPN
                     RGLQRWNFPFKSLEIAKLYLRTADYTTKSSCGIYEIENSKGRVSYKIFAGNEDLHLFL
                     KKNKDKKCKQMTPVFNVGEYKEYPHTEVRKLTSDEIKQYMSER"
     gene            18251..19645
                     /locus_tag="MIV85_002380"
     CDS             18251..19645
                     /locus_tag="MIV85_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2961712.1"
                     /translation="MRMILNKGHRIRASDKNLVYRFSMGTLLFVFVAVILLLNTKQLM
                     RTDWEHFSLLDNGFTLSLYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSVFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEQMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNLRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGFLAQARQ
                     DGTATCEAKGDGSD"
     gene            19830..21026
                     /locus_tag="MIV85_002381"
     CDS             19830..21026
                     /locus_tag="MIV85_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBY2961713.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGIMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKYYQSGELIKHREDDR
                     EYMGSTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFIDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAILSEKHEMIIKQQTTPA
                     KDLVES"
     gene            21039..21173
                     /locus_tag="MIV85_002382"
     CDS             21039..21173
                     /locus_tag="MIV85_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBY2961714.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSISKEADYEMKQLEESEDN
                     "
     gene            21174..21395
                     /locus_tag="MIV85_002383"
     CDS             21174..21395
                     /locus_tag="MIV85_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961715.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            21434..22228
                     /locus_tag="MIV85_002384"
     CDS             21434..22228
                     /locus_tag="MIV85_002384"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961716.1"
                     /translation="MGTINYFLKGIKVLMISDEMRVDILHAVFINKNFIKDEENCNYE
                     KYLLELVNKSIYFREKSNFAEYVPPKSENHGECDCNSPNYQMDFKLLESTTRLHASKE
                     LTGQIQKFCDGVIGKCPPRRPNTQMTVTRLFASLRDYDCESLHSCLTEKYEYGTIEFD
                     IQTYVKLLTFKKNLFFFFPYKFSFNTCYNFKYALDSIRIALEKDFRESNLFREKYYAE
                     YDTFLAYIYEDNLIISKFEQDGKLQMIDCIYLFKSQTYSKLYEYTW"
     gene            22327..22623
                     /locus_tag="MIV85_002385"
     CDS             22327..22623
                     /locus_tag="MIV85_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2961717.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     KDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGYWWKREEQMAKKQHHTGLTYR"
     gene            22542..23045
                     /locus_tag="MIV85_002386"
     CDS             22542..23045
                     /locus_tag="MIV85_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBY2961718.1"
                     /translation="MQETRVLVETGRTNGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSADMQEEYVELLTVFENLEALYICR
                     NVITVYHDCKSMIDVARQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENKRYLVTEN
                     SIFELPE"
     gene            23063..23566
                     /locus_tag="MIV85_002387"
     CDS             23063..23566
                     /locus_tag="MIV85_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBY2961719.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            23684..24082
                     /locus_tag="MIV85_002388"
     CDS             23684..24082
                     /locus_tag="MIV85_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2961720.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            24060..26510
                     /locus_tag="MIV85_002389"
     CDS             24060..26510
                     /locus_tag="MIV85_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2961721.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYEMIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            26510..28714
                     /locus_tag="MIV85_002390"
     CDS             26510..28714
                     /locus_tag="MIV85_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2961722.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            28711..>29594
                     /locus_tag="MIV85_002391"
     CDS             28711..>29594
                     /locus_tag="MIV85_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBY2961723.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQTMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQDIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVT"
BASE COUNT        10581 a         4441 c         6453 g         8119 t
ORIGIN      
        1 tttgtaatta agaagcttaa aatataaaat ccatatgata agcaaaatca tatattattg
       61 aatatagtta atactatata ctaatgtaat ttaaataata atgacagcta aagttcagta
      121 taatttggga ggaaatacaa tgaataatca agatatatat ataaatttat taaatatatt
      181 aagtaaagag gatataaaag tcgatgaacc tatgaaaaaa catatttcat ttagggtagg
      241 aggaccagca gatatattag ttagacctag aactgaagaa caattaaaaa atgtacttaa
      301 gttggtaaaa gaagaatcta ttccgtattt aataattgga aatggttcaa acattttaat
      361 taaagatggt ggaataagag gagtggtaat agaactagct gataatttca attcttatga
      421 gataaatgat actaggatga ctgctcagtc aggagcttta ttatcagttt tagggaaagc
      481 tctccaaaag caagaattaa aagggtttga gtttgcatca ggaatacctg gcacattggg
      541 aggagcatta gccatgaatg ctggagcata tggtggtgaa atgaaggaca tagtgaagtc
      601 agtaagactg atggatatgg aaggcaatat atttgaatta tcaaatgaac agatggaatt
      661 tgggtataga aaaagtataa tatcgaaaaa cggatatata gctttatcag cagaattgga
      721 attacaagaa ggaaattatg atgaaataaa aagtttaatg gatgatttag cgacgagaag
      781 aataactaaa cagccattaa attttgctag tgcaggaagt acatttaaga gaccaacagg
      841 atattttgca ggtaaattaa tagaagaaac tggattgaga ggtcttactt taagaggagc
      901 acaagtatct gagaagcatt gtggatttgt agtcaatcaa ggagaagcaa gtgctaaaga
      961 tattttggat ttaatatatg ttataaaaag tgctgtatat gccaagtttg gggttatgtt
     1021 ggaagaagaa gtcaaaatac ttggagagga ttaacaaatg aaaatactgg ctgattatca
     1081 tacacataca ttatatagtc atggcaaagg gactattgag gataatgtaa aggtagccat
     1141 ttctaaagga ataaaaacaa taggaatatc tgaccatagt tataaacata ttgcatatgg
     1201 tgtaaagaaa aaagatattc tcaaaatgag agaagaagta gattatttaa atgataagta
     1261 cactgatata aatatacttt taggtatgga gtgtaacata ttagatgata aaggaaatat
     1321 agatatggat gataaattta ttagagattt tgattatatt atggctggat atcattttgg
     1381 ttctactcca acatcattaa gaagcttatt aaatcattgt aataactata tttttaaaac
     1441 tgaaaaagca aaagaatata atacaaaagc tgtaataaat gcgataagta ataatgatat
     1501 ttttataatt actcatccag gagataaagg cgatgtgtat atagaagaag tagcaaagac
     1561 agcaaaaaag acaaatacta gacttgagat aaatagtagc cattcttttt tgaatgtaaa
     1621 tcaattaaat aaaataaaag ggctagaaaa taaatttata ataggctcag atgcacattg
     1681 tccagaaaga gttggtgatt ttgaactagc tatgaagact atatctgact ctaatctgga
     1741 tatatcgtta gtagaaaaca ttataatata ataaacataa gataaaaggg aggagttagc
     1801 aatgaaattt gttatagtta caggtctttc aggatctgga aaaagtgaga caatgagagc
     1861 tttagaggat atgggatttt attgtgtaga taatctacct cctgctttga taactaaatt
     1921 tgcagaatta tgttatcaac caaattcaag tattgataaa gttgctctag ggatagatat
     1981 aagagggaga aagttttttg aagcgcttca tgaaagctta aattatttag aaaaagaaaa
     2041 ttatgaatat gaaatggtat atttggattg taatgatgat gtattgttaa agagatataa
     2101 aatgacaaga agaaatcatc cattggcaaa agatatgcag attccagaag gtataaaaat
     2161 ggaaagaaag ataatggaac ctttaaagga gttatctaca tgtataattg atacaactaa
     2221 catgaaacct aaagacctta aggaagaaat aaagaaaata tattcttcag gtgaagataa
     2281 tccaaaccta actatttctg tagtatcttt tggatttaaa catggtatac ttgctgatgc
     2341 agatttagta tttgatgtaa gatttcttcc aaatccctat tatgttgaag agttaagagc
     2401 taaaactggt gatgataaag aagttagaga ttatgttatg aattctaaaa tcagtgaaga
     2461 attttatgtg aaacttttag atatgattca ttttttagta cctcaatata tagaggaagg
     2521 aaaacaacat ctagtaattg gtgttggatg cacaggtgga agacataggt cagttactat
     2581 aacaaatctt atagcggagg atttatctaa taagggatat agagttgtaa agaaacatag
     2641 agactctatg ttgcgataat ggaggcaaac atggctaaat tacttattat tgtaggaatt
     2701 ttaggttgga ttgcattaat tgtatcgtta tttatatata aaaaagcaaa aaatgaaaaa
     2761 gtaaaactat ttcaaaggtc tattgttgaa aatagagaac caaatgtggt tgtgataggt
     2821 ggaggtactg gtcaatcggt atttttaaga ggtcttaaac acactacgca aaatataact
     2881 gcaattgtaa ctgttgctga tgatggtgga ggttcaggtg tattgagaga agacttagga
     2941 atgctcccac caggagacat aagaaactgt ttattagcac ttgcaaatat agagccaaca
     3001 atgaatgaag ttatgcaata taggtttaca gaagggcttt taaaaggtca gagttttgga
     3061 aatttgtttt tggctgctat gaatgggttg tatggaaact ttgaaaaagc tgtatataaa
     3121 ttaagtgaaa tttttgctat aacaggaaga gttttaccag taactttgga agatgtaaat
     3181 ttagttgcca aattagaaaa tggcaatata ataaatggag aatctagtat acctgaagag
     3241 tcaaaaattc aaaaaagctc tattgataaa atttttttaa atccaaaaga tgtaaaacca
     3301 ttaaaggatg ttattgcatc tatttatgat gctgacatta taattatggg tcctggaagt
     3361 ttatatacaa gtataatacc caatttactt gtagagggga ttgtagacgc tattaaatcg
     3421 tctgtagctc caaaagtata tatagcaaat ataatgactc aaccaggtga gacagaaggg
     3481 tacaatgtat tagagcatgt taatgctata gtaaaacaca ctgatgagaa tttaatagat
     3541 tatgtaatcg caaataatga gatattgcca gaagaaatgc ttgacttata taaacaagat
     3601 ggagcagagc aagtcttgtt agataaaaag caaaaagata aattaaaaga gatgggtata
     3661 aaaactgtag agaagaattt aattgaaata aaaaataatt atataagaca tgatgcaaag
     3721 tatatatcta acatagttat tgagttagcc ctaaatcata attacaacaa aagttagtaa
     3781 aaaaggattt taaaaaattg tgtagaaatc cttatcatta tgttagtttt aaggagtgaa
     3841 catcgatgag agaagaggtt agtgctggtg gtgtagtcct gtttggcaat acgattcttt
     3901 tactaaggaa gttcaatgga gattgggtgt tacccaaggg aaaagtagaa gaaggggaaa
     3961 ataaccaaga ggcagcatta cgtgaagtaa gtgaagaaac tggagtaaaa gcagatatat
     4021 tgaaatattt aggtgaaata cactatacat tcaaagaaaa ctgggatgaa aatagagcag
     4081 ttcataaaac agttttttgg tatttgatgc aagcaaagaa tatggatact attccacaaa
     4141 aagaggaagg ctttattgat gctaaattta tccacctaga tagagtagta gacttagcta
     4201 ggtatgatga tgaaaaggag ataataaagg ttgccttaca agaaataaaa aaaaggttaa
     4261 agaaaaatta gttaataggt gatagatatg tctttttcaa ctgaaaccaa aaatgaacta
     4321 gcaagagtta tatctgggaa tgaatgttgt aatatagctg aattgtcagc tctagttaaa
     4381 tcagggggaa gtatacaaat tgttggatat aagaagctaa atctaaagat aacaacagag
     4441 ttaaattcaa tagcccgtaa agtatttaaa ttattaaaaa agaattttaa tatcaatact
     4501 acaatctcag taaataagaa tcaaatgcta aagagaaata acagttatgt attaatggta
     4561 acaagcgaaa tgggttcaga aatgttatta aaaaagttag gtatacttga agataaagaa
     4621 ggatttttta ctataaacaa aatttcagag aacttaatta agcatgaagg atgtaagaga
     4681 gctttcataa gaggagcttt tcttggtgga ggttctataa gcgacccaga aaagaactat
     4741 catatggaat ttgtaactaa taatgaggag tttgcagatt ctctaaaaga acttataaac
     4801 tctttaggtt ttaatagtaa aattgtggct agaaaaaata atcacgttgt ttatatcaaa
     4861 gagagtgaac aaatatcaga tttgttgagt attataggag gacaccacgc tcttttaagt
     4921 cttcaaaata ctaaaatagt aaaagaaatg agaaataatg taaacaggat agtaaattgt
     4981 gagacagcta acctttctaa aacagtaaat gcagcagtaa gacaagtaga aaatattaag
     5041 ctcatacaag agactatagg aattagcagt ttgccagaaa atttacaaga gatagctaag
     5101 attagaatcg agtatgagga tatgactctc aaagaacttg gagagatgtt agaaccacca
     5161 ataggaaaat ctggagtcaa tcatagactt agaaaaatag aagaaattgc aacagatttg
     5221 aaaaaaaaat catagcaata aattgagggg acaatctcag aataagcatt aatttataac
     5281 atataatggt atatgttgaa gttaattcct attttgagat aaaagtctct gtttttgttt
     5341 taggacatat atttgtggta aaattaaaat tataaagcag gaggtgattt aatgaacaaa
     5401 gattttgctc atcttcatgt acatactgag tatagtttac ttgatgggtt ttcgagggtg
     5461 aaaaaactta taaaaagggc taaggaacta aacatgagct caatagctat aactgaccat
     5521 ggttgtatgt ttggtgttat agatttctac aaaacagcta taaaagaagg aataaagcca
     5581 attatagggt gtgaagtcta tacagctgca cgtggattga gagataaaga cccaaactat
     5641 gacaaatatc aaggacattt agttctgtta gctaagaata tggaaggata taaaaattta
     5701 ataaaaatag tttcaacttc atacgtagaa ggtttttact ataagcctag agttgacatg
     5761 gaagaactta aaaaacataa caaagggatt atagcacttt ctgcatgcct tgcaggagat
     5821 gtagcacgtg ctttaatgaa tagaaattat gaaaaagcaa aacaatttgc tcttgactac
     5881 agagacatat ttggagaaga aaatttcttt ttggagattc aagatcacaa tttacctgag
     5941 caaaaagaag taaactctgg tttagtaaaa ttatcaaaag agactggtat accactagtt
     6001 gctactaatg atgttcacta tgtaaataaa gaagattcga aaatacatga tgtacttatg
     6061 tgtattcaaa tgggaaaaac attaaatgac ccaaatagaa tgagatttgg tagtgatgag
     6121 ttttatttaa aatcaagaga agaaatggaa gaattatttc catatgcatt agaggctatt
     6181 gacaatactg tgaaaatagc tgatatgtgt aatgtggagt ttgattttaa tactatacat
     6241 cttcctaagt atgatgttcc agaaggatat acaccagaaa cttatttaag ggagttgtgt
     6301 tttaatggat taaaagagag atatgataat cctagtaatg agatactaga gagattaaat
     6361 tatgaattag atgtaattga aaaaatgggt tatgtagagt attttttaat tgtttgggat
     6421 tttataaatt tttctaaaga aaataatatt atagtaggac caggtagagg tagtgcggct
     6481 ggttcgatag tagcatatac acttaaaata actgatatag acccaataaa gtactctcta
     6541 ttatttgagc gttttttaaa tccagaacgt atatccatgc cagatataga tatagatttt
     6601 tgttatgaga gaagagaaga agttatagat tatgtaaaga gaaaatatgg tgatgaccat
     6661 gtagcccaga taataacttt tggaacaatg ggtgcaaaag ctgcaataag agatgttgga
     6721 agggtattgg atataggcta caataaagtt gacaaggtag ccaaggaaat accatttgct
     6781 ttaggaatga caatagataa ggccctagat acaaatccta atcttaaaga attgtatgac
     6841 caagacccgg aaacaaaaga aataataaat atatcaaaac agatagaggg aatgctaaga
     6901 catgcttcta ctcatgcagc aggagttgtt atatcaaaaa atcccgtaga tgaatatgta
     6961 cctttgtaca aacatcaaga tgcaatcaca acacagttta ctatgacaac acttgaagaa
     7021 cttgggcttt taaagatgga ttttcttggg ctaagaactc ttacagttat aagagatact
     7081 cttgatttaa tagaaaaaaa tagagttata aaaaattaca cagaaaaaat agacttttca
     7141 aagatggatt atgacgaccc gaaagtatat gaaatgcttt catcaggaaa tacactaggg
     7201 gtgtttcaat tggagagtgc tggcatgaga agttttatga aacagctaaa accagacaat
     7261 tttgaagata ttgtagcggg aatatcccta tttagaccag gtccaatgga ttctatacct
     7321 gcatatataa aaaataaaag caacccaaaa gatgtaacat atctacatga aaaattaaag
     7381 cctataatgg aagttacata tggttgtttg gtatatcaag agcaggttat gcaggtcgtt
     7441 agagatttag gtggttatag ttacggacga agtgacctag ttagaagagc catgagtaag
     7501 aaaaagatgg acgtgatgga agaagaaaga caatatttta ttcatggtaa atttgatgaa
     7561 gatggtaata tagaaattgc agggtgtatc agaaatggtg tagaagagga aatagctaat
     7621 aaaatatttg atgatatgat agacttcgct agatatgcat ttaataaatc acatgcagct
     7681 gcatatgggg ttttagcata tgagacagct tatctaaaaa catattatcc agttgaattt
     7741 atggcagcat tgataaccag tgtaatggga aatactgata aggtagttga gtatataaga
     7801 gaatgtaaag cactagaaat agatgtatta cctccagata taaacaaaag tttttcaaag
     7861 ttttcagttg aaggcgacaa tataagattt ggtctagcag ccgtaaaaaa tgttggcgta
     7921 aatataataa acaatataat cgctgaaaga gaatctaatg gattatttgt agatttagta
     7981 gatttagtca aaagattaga ccaaaaagat acaaataaga gagtaataga aagtctaata
     8041 aaatgtggag cttttgataa tataagtgaa aatagagcta gtctgatggc tggttatgaa
     8101 agtttattag aaagtgtatc tatggataga aagaaaaatg ttcaaggtca aatttcttta
     8161 tttgatgctt ttggagatag tgaggaagat agtgattttc aacaaatata cagtttgcct
     8221 aaaaggcaag agtacgaaga aagagagaga cttaaccttg aaaaagaagt cttgggaatg
     8281 tatgtaagtg gacatccttt atcacaattt gaaaaagaac tacaagaaaa aacatctatg
     8341 gataatggaa aattaaattc attaaaagag gaagaagagt catacctaca aatgaatgaa
     8401 acagatgtta taatgggtgg aatgattgta actaaaacta ttaaaacaac aaaacgaaat
     8461 gaaattatgg catttattga attagaagat ttgtatggtg ctatagaaat aatagttttt
     8521 cctcaattat tacaaaagta taatgtcatt ttgaatgaag ataatataat atatgtaaaa
     8581 ggaacattaa gtataaaaga aggcgaaaat gcaaaactta tagctagaga gataaaagat
     8641 ataaatgatg atactgactt tgcagataga aactacaatt caggaagaac tagaaatgta
     8701 gaaaatatta agccagaaag tggtaaaaaa ttgtatttga aaatagatag tatgtctgat
     8761 actgatacaa ctaataatat tgtagaaata gccaaacaat atccaggtaa tgacagtata
     8821 tacttatacc ctatggatga aaatataaat ggtaaacgta aagcatataa aatgaccggg
     8881 gcattgactt gtatatgtga tgaatttata aataacttag aagagttact tcctaaagat
     8941 aacataaaag taaaagcttg attttttata taaaaatcta aatatattat aataatatga
     9001 aaaatattgt ccgttttgtg atataatatc acaaaatgga catttaagga catttaattt
     9061 ttttagtctt gatgggatta aaaagtgata tagggacaaa aaaagtccat tagaatacaa
     9121 taacaatgat tataataaaa aattgacata aaatccaagg aggtaaaaaa tgaaaactat
     9181 aggattacta acaagtggag gagatgctcc aggaatgaat gctgcgatta gagcggttgt
     9241 aagatcagca atatattatg gatgcaaagt atatggaatc aatagaggat ataagggatt
     9301 actagaagaa gatttaactg aaatgaactt atcttctgtt ggagatatta tacacagggg
     9361 aggaactata ttaaaatctt ccagatgtga agaatttaaa acagaagaag gtagattaaa
     9421 agcagtaaaa attcttaaaa agtataaaat tgattgctta gttgtaattg gtggagatgg
     9481 ttcatttgca ggagcccaaa aacttagtga cttaggattc ccagctatag gcataccagg
     9541 aactatagat aacgatttag catatacaga ttatactata ggatttgata ctgcaatgaa
     9601 tactattata gatgctatag gtaagataag agatacatca tcatctcatg aaagagttaa
     9661 catagtagaa gttatgggaa gacactgtgg agatttagct ttatatgcag gtcttgcagg
     9721 aggagcggaa actataatag taccagaagt agaaattaca gtagatgaag ttgctctaag
     9781 attaaagact actcaaaaaa gaggtaagag acatagtata atcgttttag cagaaggagt
     9841 cggaagtgct agtgatttag aaaaggaact taaaaaagag tcaggagcag atttaagagt
     9901 cactgtattg gggcatgtcc aaagaggagg aagcccaact gtatctgata gaatactagc
     9961 aagtagactt ggagtaagag cagtagaatt attattagat ggaaaatcag ctagagttgt
    10021 aggaataaaa gaaaacaaaa taattgattt agaaataagt gaagctttag ctcaaaagaa
    10081 agtatttgat aaagaagctt atgagatggc aaaaatatta tctatataag ttttagtatt
    10141 aaaaataaat ctgtggaata atatctcagg aggagcaaat atgttaaata atgtaaagaa
    10201 gacaaaaatt gtttgtacac taggtccagc atcacaaagt gaggaagttt taactcaact
    10261 tatgcaaaat ggtctaaatg tgtgtagatt taacttttct cacggttcgc atgaagaaca
    10321 taaagaaaga attgatatgg caaagaaagt tagagaaaaa ttaaataagc cagttgctat
    10381 attattagat actaaaggtc cagaaattag aacaggtaac tttgaagacc cagaggtatt
    10441 tttagaagaa gggcaaaagt tcactataac tatgaaagat attatgggga ctaaagaaat
    10501 gtgtacagta agctataaag gtcttgctga agacgttaaa tcaggagatt ctatactaat
    10561 agatgatggt ttagttggct taagagtaaa agaaataaat ggagaagata tagtttgtgt
    10621 tgttgaaaat tcaggaatag ttaaaaatca taaaggagta aatgtacctg gtgttaagat
    10681 aaatttacca gcaataactc ctaaagatat aagtgatata gagtttggaa taagtcaagg
    10741 aatagattat atagctgctt cttttgtaag aaaggcatct gatgtactag caataagaga
    10801 agtattagag aacaataatg caactgatat acaaataata tctaaaatag aaaaccaaga
    10861 aggtgtagag aacctagatg aaatattaaa agtttctgat ggtataatgg tggctagagg
    10921 tgacttaggt gttgagatac caactgaaga gatgccaata gttcaaaaaa tgatgataaa
    10981 aaaatgtaat gaattagcaa agccagttgt tactgccact caaatgcttg attctatgat
    11041 aagaaatcca agaccaacaa gagcagaagt tacagacgtt gccaatgcta tatatgatgg
    11101 aacagatgcg ataatgttat ctggagaaac tgctgctgga aaatatcctg tagaggcagt
    11161 aaaaatgatg gctacaatag caaaaagaac agaagagact ttagattatg atagattact
    11221 aaaggaaaat ggtactaaca atgttactgt aacagatgca ataagccatg caacttgtac
    11281 aacagcagta gatttaaatg catcagctat aataacatct acttcttcag gatatactgc
    11341 tagaatggta tctaaattca gaccaaaatc tccaataata gctactacaa ataatgaaaa
    11401 gactatgaat aaattagctc ttacatgggg agtatatcca gttaagtctt ctgttgcagg
    11461 aaatacagat gaagttatag aaaaggcaat tgaggcagct agacaagctg attatataga
    11521 taatggggaa ttagtagtta taactgctgg agtaccagta ggagtaagtg gaactactaa
    11581 tttaataaag gttcatgtaa taagcgaaga aatcgtgcaa ggtataggtg taggtactca
    11641 aacagtagaa ggtaaagttc gtataataaa gaatggaaat gcttgtgtag actttaatga
    11701 aggcgacata cttgtttcta ctgctactga tgctgaaatg aacaattata tagaaaaagc
    11761 aggagctgta gtaactgaga atggtggaat gacatcacat acagctattg taggtataaa
    11821 tttagatata ccagttattg tgtctgcagc tgatataaca aatctagtaa aagatggaga
    11881 agttgtaact gtggatgcat caagaggcgt ggtatataga ggttcaacta gagttttata
    11941 agaaaaataa taaatttatt tactaagggg ctttataagc tccttttttt ttggtaaaat
    12001 aaaatattgt agcttagtaa aaaatatagt ttaattaata gcaatatttt aatataaatt
    12061 taaagaaaaa agtttgtaaa gatttaaata taatagattg attggagggt gatttatgct
    12121 ttcgaaaaac gagatgtata ttgtagatat agtagacatt ggtcaaggcg gagtaggagt
    12181 aggaaagtac aatggtatta cagtttttgt agagggcgga ttaatacatg ataaagttaa
    12241 agttaggatt aataaagtaa agaaaaatta tgctgtggga gatattgttg agataataga
    12301 aaagtctcca ttcagggtga aaagagtgtg tagtgacaat cttagggatt gtggagggtg
    12361 tcagatacaa gacttagatt ataataaaca acttgaaatg aaaacaaatg aagttaaaca
    12421 agtactttcg agaataggta agttagagga tgtagaagtt catgacacta taggaatgga
    12481 taatccatat agatatagaa ataaagcaca atttccaata caaaagaata atggtattcc
    12541 aattattggc ttctataaaa agaagactca tgatgtaata tcgacagaaa aatgcgtaat
    12601 acaacatgag ataaatgata aaattgttaa aataataaaa acatatataa gggcctataa
    12661 ggtaagcata tatgatgaaa agactcacac ggggttgatt aggcatttag taacaaaaat
    12721 aggttttaca actaaagaag taatggttgt attagtagca aatggaaaca aacttccata
    12781 tcttaaagaa ttagcttcag tgcttaagga aaatatacct ggatttaaga ctttggttgt
    12841 aaatgtaaat caaaaagata cgaatgctat tctaggaaga gaaaatatag ttatatatgg
    12901 agatggaaaa ataaacgatt atataggaga cttagtgttt gagatttcac cattatcatt
    12961 tttccaagta aaccctgtcc aaactaaagt attgtatgat aaggctcttg aatatgcaaa
    13021 tttaaatgat actgatactg tttttgatat ttactgtggg ataggtacaa tatctttatt
    13081 tttggcacaa aaggctaaaa aggtttatgg aatagaaatt atagatgatg ccataaaaga
    13141 tgctaagata aatgctaaat taaacaatat acataatgct gaattttatg ttggaaaggc
    13201 agaggaaatt gtacctaaga tgtatagaga gggtaagact gccaatgtag tcgttgtaga
    13261 cccacctaga aagggatgtg acgaaaaggt attagagact attgtttcaa tgaatccgga
    13321 aagaattgtc tatgtttctt gtaatccttc tactttagca agggatttag attatctaaa
    13381 tgttcacgga tttaaatgtg ttgaggcaca acctgtagat atgttccctc attctacaca
    13441 tatagagact tgtgtgttgc tacaaagacg aactatgtag aaatccttaa ttttaggcac
    13501 ttttttaagc atatagtctt tacgagcgag ggcgataaaa tcagaaataa agagataaaa
    13561 aactatatca atgtttcagt agttgttgat atagagtgtg ggaacacaaa caattaaata
    13621 ttagatttga ggggtacttg taaaaagtat cccttttcaa tgtaagacgt tcaatattga
    13681 gcgtctattt ttttacccaa aatgaaagga gcatttagaa ttatgaaaaa gatattgaaa
    13741 cgattgtgta cgggagtact tgcctttgcg actgtcgtta ctgctttacc gagtaccgcc
    13801 gtccatgcag aaagcaagca atactggacg gaatcagagg aacgtgtcgg tatcgtagaa
    13861 aaagtaatga atgacggttc gattggttct acctttaacg agggacattt gactgttgag
    13921 ggcgaggacg cttactgtat agacatcaat acagatttta agaatggcta caagaccaga
    13981 gctgacgcaa gcacccgtat gagtgccgac cagatttcag atgtggcgtt atccttagag
    14041 tatgtcaaac agtatggcga agcacacaag gaattgaact acaagcaagt ctatctgttg
    14101 gaacaatgtg ttgtctggca gagattgagc gtacatcttg gctggcaatg cgacaacgtg
    14161 cgagcttctt atgatgaaat accaaaagca actcaggacg aagttttcgc tggtgctaaa
    14221 gcctttgtga aagaaaataa aggacgctat gaatgtggcg gttatatcta ctctggcgag
    14281 gggcaggaat tgggacaatt ctgggcgaag ttaaatgtcg gaaatgcaaa actgcaaaag
    14341 acttccagta ataccagcat tacagacggt aacgggaatt actcaatcgc tggtgcgacc
    14401 tatggtgtct tttctgataa ggactgcacg aaacagcttg ccacccttac gactgataaa
    14461 aacggaaata cagatgttgt agaggtaaaa gcaggtacag tctatattag ggaattatcc
    14521 gcaccagcag gatataaagt tgatacaacc gtgtattcct taaaagttga agctggaaag
    14581 acagcgacct tgaacgtatc agatacacca aaagtaacgg acaccttgat tgagcttttc
    14641 aagattgata tggaaacgca gaaagacaat ccgcagggaa acgcttcttt agagggtgca
    14701 gagtttacat ggaagtatta tgctggcttc tataacaaag acaatctccc tgccgaagct
    14761 actcgtacat gggttacaaa gacaatcgct gaaacagaca gtgacgggac aactcactac
    14821 atcacaaaat tagcggacgc ttacaaggta tctggcgaca gcttctatat gcaggacggc
    14881 aaagcgattc ttcctttagg aacactatct gttgaggaaa caaaagctcc aaacggctac
    14941 ttgctggacg gtgcatatat gcaggctggc gataagtctg aacagataaa aggcttatac
    15001 cttacacaaa ttacagagga cggcgacctt gctgtattga cgggaagtaa ccagttttcc
    15061 gtatcagaca aggttatccg tggcggtgtg aaaattcaga aaagagattt agaaacgagc
    15121 gataccaaac cacaaggaag tgccactttg aaagatactg cttttgacgt catttcctta
    15181 aatgacaatt ctgttttggt tgagggcaag ctatataaga aaaatgaagt ggtaaagaca
    15241 attcgtacag atattgaggg tgtggcttct acttctgctg accttttacc ttatgggaaa
    15301 ttccgtatcg ttgagagtga agctcccgac ggttacttga cagacggtgc gaagccgatt
    15361 gactttgcaa tcacagagaa tggaaaaatc gtggacttaa ccgacgaagc ccactctatc
    15421 tacaatcaga ttaagcgtgg ggatattgag ggagtgaaaa tcggtgcagg cacacacaag
    15481 cgtcttgctg atgttccctt taggatcaca agcaagacga cgggagaaag tcatgttgta
    15541 gttactgatg ataacgggca attctccact tctgctgaat ggacttctca taagcacaat
    15601 actaacgcag gcaagaccag cgaggacggt gtgtggtttg gaacttctga agcagacgac
    15661 agcaaaggtg cattgcctta tgatacttac atcattgaag aaatgcgttg cgatagtaac
    15721 aaaggctttg aacttatccc accttttgaa atcgtggtat caagaaataa ccttgtgatt
    15781 gatttaggga ctttgactga tgaatacgaa aaagaaatct ctatccatac cacagcgacc
    15841 agcaaagaca gcgaaaagac tatccttgca ggaaaagagg taacaatcgt cgatactgtc
    15901 aaattagacg ggcttacaaa aggtacaaaa tatcagctca aaggctggca gatgttaaag
    15961 gaagaaaatg cagagcttat cattgacgga aaacgtgtgg aaaatgacta tacttttatc
    16021 gctgatgatg aagaaatgaa agtggaaatt tcttatacat tcaatgcgtc cgagcttggc
    16081 ggtaaaaatc tggtaacatt cgaggaatta tacgatttaa gcaatccaga cgaacccgtg
    16141 aaagttgcgg aacacaaaga cattgaggac gacggacaaa ctgtattgat tacagaacgt
    16201 atcatcaaga tacatacgac tgctaccgac aaagacggca acaaagagat tgaagctgga
    16261 aaagacgtta caatcattga taccgtaacc ttagagggct tggaagtcgg tacacagtac
    16321 aaacttgtag gctggcagat gttgaaagaa gaaaatgcag aacttcttat caatgggaaa
    16381 cgtgtggaaa gtgattacac ctttaccgct gacagcgaaa ctatgaaagc ggaagttgcc
    16441 tttacctttg acgctacttc ccttgacggc aaacagcttg taacttttga agaattgtat
    16501 gatttaagca atccagacga gccgaagaaa gttaccgagc ataaggatat tgaggacgag
    16561 ggacagacga ttacttttaa tgaaaaacca gaagtcccag agaaactcga aacaccgcag
    16621 acaccagaaa agccaaacag acctagcgac agtcctaaaa cgggcgacag tacaaatgtc
    16681 atggcatttc ttgtgatgtt gcttacatct gctggtggac tggctggaac atatctttac
    16741 aaacgccgta caatgaaaaa atcataaggc ggtaacggta tgatgaaaga aaaatcacgt
    16801 tctccgccga aactgtcaaa cggcagacaa gccagaataa aaaattacaa tcataaactt
    16861 atcaaatata gaaagaaacg aggtaaaaca atatggaaat gaaatatgtc gtgccagata
    16921 tggcacagtc ttttggaact cttgaatttg caggcgaaag cgagcctatc tttgaaaggg
    16981 ataaaaacaa ccgcaaggtc atagccagac gaagctataa cctttattct gacgtacaga
    17041 aaggcgaaaa tgttgtggtg gaaattcccg tgcaggctgg cgaaaagcat ttcaagtatg
    17101 aacagaaagt aaaacttgtc aatccgaagt tatacggcag agggtacgca atcggggatg
    17161 tgggacatac cgattatgta ttagtagctg atgatattgt agcagttgaa gaaaagtaaa
    17221 ggagtgaaga atttatgaga ttatcaaatg gatttgtcat tgacaaagag aaaacatttg
    17281 gagaattaaa atttacagcg gtgcgtgatg tgttcttgca aaatgaggac gggacaccga
    17341 gtacccagct taaaaagcgt atctatgatt tgaagtgcag tctgcatggt ggaattatcc
    17401 ccgtgtccgt accgccagaa gtaccgttaa gggaatttcc ttacaatgca gtcgtggagc
    17461 ttgtcaatcc cgtagccgat acggtatcac gaaaaaccta tacgggtgca gatgtggact
    17521 ggtatgtaaa ggcagaagat attgtactga agaataaagg caatcagaac acaggcactt
    17581 cacagaacca tacaccgcag ggacaaccga aaaaatagac ttgctgaata gattttcgtt
    17641 gtagaggata tacggaactg ttataatatg ggtatgaaga aagcgacaaa ttagaatttg
    17701 ataaggagcg aaaagaaaaa tgtgtgaaga atgttactct gatgaaaata gaataacacc
    17761 attactaaat cccttggact gcttagaaaa ccacactcaa tatatttgtg gaacttgtgg
    17821 acgttgcatt tgtattgaac atgacccaaa cagaggatta caaagatgga attttccttt
    17881 taagtcattg gaaattgcaa aactttattt acgaacagcc gattatacaa cgaaaagttc
    17941 atgtggtatt tatgagatag agaacagtaa aggcagagta tcttataaaa tattcgccgg
    18001 gaatgaggat ttacatctat tcttgaaaaa gaataaagac aagaaatgca aacaaatgac
    18061 acctgtgttt aatgttggag agtataaaga atatccacat acagaagtac gaaaattgac
    18121 ttctgatgaa ataaaacaat atatgagtga acgttaaatt ccagtttgac aacttcatat
    18181 ccatgcacac aaagcagtta gtctatacga ttgactgctt ttttcatacc cagaaaggag
    18241 tgattgattt atgagaatga ttttaaacaa aggacaccgt atcagagcca gcgataagaa
    18301 ccttgtctat cgcttttcaa tggggacact cctgtttgtg ttcgtagcgg ttatcctgct
    18361 attaaataca aaacagctca tgcgtaccga ctgggaacat ttcagcttat tagacaatgg
    18421 ctttacgctt tccctttaca acttcataac catactgata gcgactggtg tttgtgcatt
    18481 ggtcgctttt ctgtattacc gcttctgtta cgacagtttc aaaaagctac tgcaccgtca
    18541 aaagctggca cgaatgatac tggaaaacaa gtggtatgaa gctgataccg tacaagacag
    18601 cgtttttttt actgacctgc aaagcagatc aagggaaaaa atcgtctggt ttccaaagat
    18661 ttattatcaa atggaaaagg gactgcttca tatccgctgt gaaattacgc tggggaaata
    18721 tcaagaccag cttttacggt tagaggataa attggaaagt ggcttgtatt gtgagctgac
    18781 cgacaagacc ctgcatgacg gctatatcga atataccctg ctttatgata tgatagcgaa
    18841 ccgcattacc attgatgaag tacgggcaga gaacggctgt cttagactga tgaaaaatct
    18901 tgtctgggaa tatgacgcac tccctcacgc tctgattgct ggtgggactg gtggcggtaa
    18961 aacatatttt cttctgacgc tcattgaagc cctactgcat accaacgctg tcctttacat
    19021 cttagacccg aaaaatgcgg acttagcaga cttgggaaca gtcatgggaa acgtgtatca
    19081 caccaaagaa gaaatgatag actgtgtcaa tgctttttat gagggcatgg tacagcgaag
    19141 cgagcaaatg aaacgacacc cgaactataa gacgggcgaa aattacgcct atctgggact
    19201 gccaccctgc tttcttatct ttgatgaata tgtggcgttt tttgaaatgc tggggacaaa
    19261 agaaagtgtg ggcttactta gccagttaaa gaaaatcgtc atgttaggac gacaagcagg
    19321 ttatttcctt atcgttgcct gccagcgtcc agacgcaaaa tatttctcgg acggtatcag
    19381 agataacttc aatttacgtg tgggattggg gcgtatcagc gagttaggtt acggtatgct
    19441 gtttggttca gatgtgaaaa agcagttttt ccaaaagcgt atcaaagggc gtggctattg
    19501 tgatgtggga acaagcgtca taagtgaatt ttacacgcct ttagtcccga aaggacatga
    19561 ttttttgcag acaatcggtt ttcttgcaca agcaaggcag gacgggacgg cgacgtgcga
    19621 agcgaaaggc gacggctcgg actagccgtt gctggtgtgg cgtaagccac gccagcaggt
    19681 aaaacccctc ggtatctaac agaggggtac gtttgcaaat agacaataga caaaaaaaca
    19741 taggaaacat aaggcttctg gcatggtttc ctagcaaaaa tcggctgtga agtcgcctta
    19801 aaaaacttca cacttgacag attgggggta tggttctgaa tgaagaacaa tggataaaag
    19861 aattacggga gaagcggatt gcttacggta tctcacaagg caggctggcg gtagcttctg
    19921 gtatcacaag ggaatatcta aacaagatag aaagcggaaa aatgaagccg tcaaaagaac
    19981 ttctggaaac tttgcataaa gaactggcaa ggttcaatcc agaagcaccg cttaccatgc
    20041 tgtttgatta tgtgaaaatt cgttttccca cgctggatat acagcacatc atcaaagaca
    20101 tattaaaact gaatatcaat tatatgctcc atgaagatta cggacattac agttatacgg
    20161 agcattattc attaggggac atctttatct atacgtcggc tgacgaagaa aaaggtgtcc
    20221 ttttagagtt aaagggtcgg ggttgcaggc agtttgaaag ttacctgctg gcacagcaaa
    20281 gaagctggta tgactttctt atggacgcac tcatagacgg aggcattatg aagcgtatcg
    20341 accttgctat caacgaccat acgggcattt tggatattcc agagcttgcg gagaaatgca
    20401 ggaaacggga atatatcgga aagtccagaa gctataagta ttaccagtcg ggcgagctta
    20461 tcaagcacag agaggacgac agagaatata tggggagtac cctttatctt ggttcgctga
    20521 aatcagatgt gtatttctgt atctatgaaa aggactatga gcagtatgtc aaattaggta
    20581 cacctctgga agaagccgac attatcaacc gttttgagat acggcttaga aatgaacgtg
    20641 cttactatgc agtacgagat ttgctgacct actatgacgc agagcagacc gctttttcta
    20701 tcatcaacca gtatgtgcgg tttattgatg aagaaccaga caagcggaaa aatgactgga
    20761 aactcaatga ccgctgggct tggtttattg gcgataatcg gcaaagtctg aaactgacga
    20821 caaaaccaga accttacacc ttagaccgca cattgcgttg ggtacaaaga caggtagcac
    20881 cgaccttgaa aatgctgaaa aagattgata agggaaacgg tacagactac atggaaacga
    20941 ttgaaaagca ggcaatcttg agtgaaaagc atgaaatgat aatcaaacag cagacgaccc
    21001 ctgcaaaaga tttggtggaa agttaggagt gataaaaaat gtgggaatta gtaaaagact
    21061 tcctgctggt atctatggga atgggtatcg gcgtagtctt gatgtgtatt ttgagtatca
    21121 gcaaagaagc tgactatgaa atgaaacaat tagaagaaag cgaggacaat taaatgaatt
    21181 tcggacaaaa tttgtatcaa tggtttttat caaatgcaca gagcttagtg cttatggcga
    21241 ttgtggttat cggtatctac ttagggttca agcgtgagtt ttcaaaactt attggcttct
    21301 tggtagttgc ccttattgct gtcggcttag tattcaacgc tggcggtgtg aaagatgtac
    21361 tgttagagct gttcaataag attattggag cataacgaat tttattgttg ctgtaatatg
    21421 agaatgttat aatgtgggta cgataaatta ttttttgaaa ggaataaaag tgcttatgat
    21481 ttcagatgaa atgagagtgg atattttaca tgcagtattc ataaacaaaa attttattaa
    21541 agatgaagaa aattgtaatt atgaaaaata cttgttggaa ttagttaata aatcaatata
    21601 ttttagagaa aaatcaaatt ttgcagaata tgtaccacct aaatctgaaa atcatggaga
    21661 atgtgattgt aactcaccta attatcaaat ggactttaaa ttacttgaaa gcacaacaag
    21721 acttcatgct tcaaaagaac ttactggtca aatacagaaa ttctgtgatg gtgtaattgg
    21781 taagtgtcca ccgagaagac caaatacaca aatgactgta actaggttat ttgcttcgtt
    21841 gcgggattat gattgtgaaa gtttacattc ttgtcttaca gagaaatatg agtatggaac
    21901 gattgaattt gatatacaaa cctatgtgaa attgcttact ttcaagaaaa acttattttt
    21961 cttttttcca tacaagttta gttttaatac ttgttataac tttaaatatg ctttagacag
    22021 tataagaatt gctttagaaa aagattttag agagtcaaat ctttttagag aaaaatacta
    22081 tgcagagtat gatactttct tagcatatat ctatgaagat aatctgataa taagtaaatt
    22141 tgaacaagac ggcaagttac aaatgattga ttgtatatat ttatttaaaa gtcaaacata
    22201 cagtaaactt tacgagtaca catggtaaat cagttacact taaacaaatt catacttaca
    22261 cacaaagcag ttagtcttag gattgactgc ttttttctta cctaaatttc agattggagt
    22321 gatgaaatga acgatatttt taaagatatg caggcaaaag tcggctgtga atacatttcc
    22381 gacctgccct cttacaagcg taaggtgtgg catgaaatga aacggctgaa ccctgccgac
    22441 tatgaagaaa aacagttgaa agatttttct aaatatgtgt ttggtatgtc ataccagacc
    22501 ttaaaagatg tgatgaaaca acagaaagga cgtgaggaac aatgcaggaa acaagggtac
    22561 tggtggaaac gggaagaaca aatggcgaag aaacaacatc atactggttt gacttaccga
    22621 tagatgttgc agagtttgaa gaaaagttag gtgtcggtgc agaaagtcaa gattaccgca
    22681 ttatcgaaaa ggtgttgcct tatgctgatg aagtccacga acacaccagc gtgtaccagc
    22741 ttaacgaatt agattttatg taccgccagc tatcagccga tatgcaggaa gaatatgtag
    22801 aacttcttac cgtgtttgag aacttagaag cactttatat ttgcaggaac gtgattaccg
    22861 tttatcacga ctgtaaaagc atgatagatg ttgcaaggca aaagctgatg aacgacccga
    22921 cattcaaaca tttatccgag gactgtcaag catactattt cgattttgaa gcctacgctt
    22981 ctcacttact tgaaaacaaa cgctatcttg taacggaaaa cagtatcttt gaactgccag
    23041 aataggaaat gaggtggtgc ttatgattga tgatatggcg gtttatattg ctaatcttgg
    23101 cagatacaat gagggatatt tagtcggtgc gtggttcact ttccctattg acgaggaaga
    23161 tgtaaaagaa aaaatcggct tgaatgaaca gtacgaagaa tacgctgtcc atgataccga
    23221 caactttcct atcgacatag gggaatatgt ttccattgaa gaactcaatg aaatgtatga
    23281 aatgatagag gaacttcccg actatatcgt agagtgtctg gacgaattta tcagccacta
    23341 tgggacgctg gaagaagtcg tggaacataa ggacgatatt tatttttatc ccgattgtga
    23401 aaccatgaca gatgttgcct actactacat agacgaattg aacgcacttg gggacattcc
    23461 agctaactta cagaactata ttgactatga agcctacggg cgagatttgg atatgggtgg
    23521 tcgattcatt gaaacaagcc gaggtatctg tgagatacca tattaacgct ggaagatcag
    23581 caacaagcat tgttgctact gacagcgtat ttctctttaa gggacagtct gaaaatggct
    23641 gtccttttct ctttgaagaa cttacgaaag gggctgaaag aacttgaaaa agattaaaag
    23701 ctacacgggt atctggaacg tggaaaaagt cttatatgca atcaatgact ttaacttacc
    23761 ctttcccgtt acctttacac agattacatg gtttgtgatt acggaattta tcatcattct
    23821 gtttggggat atgcccccac tttccatgat tgagggagca tttctcaaat acttcggtat
    23881 tcccgttgct ctcacttggt ttatgtcgca gaaaaccttt gacggaaaga agccgtacag
    23941 ctttttgaaa tcacagataa cctatgcctt gcgacctaaa atcacttatg caggaaaagc
    24001 cgtaaaactg cataagcaga tattgaatga aacaatcacg gcagtaagga gtgtgaacta
    24061 tgttcccgat aaaatatatt gacaataacc ttgtctggaa caaggacaat gaggtgttcg
    24121 cctactatga gatgataccg tacaactatt cttttctatc cgcagagcag aaatttatcg
    24181 tgcatgacag ttttcgacag ctaatcgcac agtcccgtga gggaaaaatt catgcgttgc
    24241 agattgccac agaaagctcc attagaagta tgcaggagca gtcaaagaaa ctggtaacag
    24301 gcaaacttcg tgaggtggca gtccaaaaaa tagacgaaca gaccgaagcg ttagtatcaa
    24361 tgattgggga caatcaagtg gactaccgct tttttcttgg ctttaagctc atggttacgg
    24421 aagaacagct caatctgaag aacatcaaaa aatcggcatg gctgacgttc aaggaatttc
    24481 ttcatgaagt gaaccacacg ctgatgaatg attttgtttc catgccgaat gatgaaatca
    24541 accgttacat gaaaatggaa aagttactgg aaaataaaat ctcccgtcgc tttaaggtgc
    24601 gtcgcttgga aatccatgat tttgggtatc tcatggaaca tctttacggc agggacggta
    24661 tcgcctatga agattatgag taccagctac caaagaagaa attgaagaaa gaaacgctga
    24721 taaaatacta cgaccttatc cgtccgacaa ggtgtgtgat tgaggaaagc cagcggtatt
    24781 tacgattgga acatgaggac aaggaaagct atgtgtccta ttttaccgtc aatgtaattg
    24841 tcggggagtt ggattttccg tcctctgaaa tcttctattt ccagcaacag caattcacat
    24901 tccccgttga tacttctatg aatgtagaaa tcgtggagaa ccgtaaggca ttaacgacag
    24961 tccgcaacaa gaaaaaggaa ttgaaagatt tggataatca cgcctatcaa gcaggaagtg
    25021 aaaccagctc aaatgtggtg gacgctttag acagcgtgga cgagctggaa accgatttag
    25081 accagagcaa agaaagtatg tataagttaa gctacgtcat acgggtgtct gcacccgatc
    25141 ttgacgagct gaaacgccgt tgtgatgaag tcaaggactt ttacgacgac ctcaatgtaa
    25201 aactggtgcg tcctgctggc gatatgttgg gacttcattc tgaattttta cctgccagca
    25261 agcgatatat caatgactat gtgcagtatg taaagtcaga cttcttggct gggcttggtt
    25321 ttggtgcgac ccagcagtta ggggaaaaca cgggtatcta tatgggctat tccgttgata
    25381 cgggaagaaa tgtgtacctg caaccgtctt tagcttcgca gggagtaaaa ggcacagtta
    25441 ctaatgccct tgcttctgct tttgtgggaa gtcttggcgg tggaaagtca ttctgcaaca
    25501 atctacttgt atattatgcg gtgctgtttg gcggtcaagc acttctgtta gaccctaaaa
    25561 gtgagcgtgg caactggaaa gaaacgctcc cagagatagc ccatgaaatc aatatcgtaa
    25621 accttaccag cgacaaggac aatgcaggac ttcttgaccc atttgtgatt atgaagaatg
    25681 tgaaagacgc tgaaagtctg gcaatcgaca tcttaacatt ccttacgggt atttcctcta
    25741 gggacggcga aaaattcccc gtgttacgaa aagcggtgcg ttctgttacc cagagtgaaa
    25801 atagaggact gttacacgtt attgaggaat tgagaaaaga agataccgct atctcacgca
    25861 atatcgcaga ccatatcgac agcttcacgg actacgactt tgcacacctg ctgttttcag
    25921 acgggacggt agaaaatgct ataagccttg ataaccagct caatatcatt caagtagcag
    25981 accttgtact gccagataaa gataccactt ttgaggaata cacgaccatt gaattattgt
    26041 cggtgtctat gctgattgtg attagtacct ttgcccttga ttttatccat tcggacagaa
    26101 gcatttttaa gattgtagat ttggacgaag cgtgggcgtt cttaaatgtg gcacaaggcg
    26161 aaaccctatc aaataagctg gttcgtgctg gacgagctat gcaggcaggc gtttatttcg
    26221 ttacccagtc tgcctatgac gtgtcaaagg aaagtctgaa aaacaatatc ggtttgaagt
    26281 ttgcatttcg ttctactgac atcaacgaga taaagcagac cttagaattt ttcggtatcg
    26341 acaaggacga cgaaaacaac cagaaacgct tgcgtgattt ggagaacgga caatgtttat
    26401 tgcaggactt atacgggcgt gtcggtgtgg tgcagataca cccagtcttt gaagaattac
    26461 tacacgcctt tgatactaga ccgcccgtac agagaaatga ggtggagtga tgaaagaaag
    26521 gatacagagt gcgttcacaa aaaggaagat acttcacttt ctcaaaatgg ctctgttcgt
    26581 ggtggcactt tcccttatcc tgctttcact tctggggacg gtggctcatg cgacggggct
    26641 tgtggacgat accataaacg cagaaaatct atattcaaaa tatccgcttt ccaactacca
    26701 gcttgatttt ttcgtcgata atagctggtc gtggcttccg tggaactggc tggacggtat
    26761 cggaaaatcg gtacagtacg ggctttactg cattaccaac tttgtctgga cgataagcct
    26821 ttatttaagc aatgcaactg gctatgtggt gcaggaagcc tataaacttg attttattaa
    26881 cgatatggca gacagtatcg gaaaaagcat acagaccctt gcaggcgtta ccgagaacgg
    26941 cttttcttct acgggcttct atgttggttt cctgcttctt attatcttag tggtgggaat
    27001 gtatgttgcc tatacgggac tgataaaacg ggaaaccagc aaggcacttc acgctgttat
    27061 caactttgtg gtggtgttcg tgctgtccgc ttcgtttatt gcctacgctc ccgactacat
    27121 caagaagata aatgaatttt catcagacat cagtaccgct tcgcttgatt tgggaacaaa
    27181 aatcatgctc cccaactctg acagcgaggg caaggacagc gtagacttga tacgggacag
    27241 cctattttct attcaagtac aacagccgtg gctactctta cagtttggaa acagcaacgc
    27301 agaggaaatc gggacagacc gtgtcgaagc tctcgtatcg gcaagtccag aggacgagga
    27361 cggaaagacc agagaagaag tcgtgaaaac agaaatcgag gacaacgaca acaacaatct
    27421 gacgataccg caggtggtaa accgtttagg tatggtgttc ttcctcttgt tctttaatct
    27481 tggtattacg atatttgtat tcttgcttac gggtatgatg ttgttcagcc agatactttt
    27541 tattatcttc gctatgtttt tacctatcag ctttctactt tccatgatac cgagctatga
    27601 aagcatggca aagcaggcaa tcgtgagggt atttaatacc ataatgacac gggcaggaat
    27661 aacgctcatt gtaacggttg cgtttagcat ttccagtatg ttttataaca tatccacgga
    27721 ctatccgttt ttcatggtgg cgttcttgca gatagtatgt ttcgctggta tctatatgaa
    27781 gctgggcgac ttaatgagta tgttttctct caacgctggc gacagtcaaa gcatgggacg
    27841 caggatattc cgcagaccgt atctgttcat gcgacatcgg gctaggcgta tggaacaccg
    27901 tattgcaagg gctgtaagtg ctggcggtat ttcgggcggt gtggctggtg cggtagctgg
    27961 aagtgccgtt gctggcaaga gagccgaaag aaaaaatacg gcttctaaag aaaatcgggg
    28021 caataccact tccagtatgg gacagcgtgc aggctcaaag gtgggtgctg tcttagatac
    28081 gaaaaataaa gtgaaagaca aggcaaacgc tgtcaaagag aatatcaagg atatgcccac
    28141 acagaccgct tatgcggtgt attccgcaaa ggaaaaggca aagtccagcg tgtctgattt
    28201 caagcgtggt atggtgcagg aacagcagtc cagacagacg ggacgcttgg aaaagcagga
    28261 acagcataag aaaagtatcg ctgtcaagcg tatggagctt caaaaggcac aagaagcaag
    28321 gcaggcacag cgaaaggctg acggatcagc gacaacggga gctacccgtc cccatgagcg
    28381 accagccaca gcttcaaccg tttcaaagac gggtgcggaa aaaatgcagg aagtcaaacg
    28441 ccctgccaca actccgacta cgaaagcaag cgaaccagtt aagacaagcg gtgtcaaaga
    28501 acgtccgcta tcttctagta ctcctgacgg gaaagcgacc caatcgacat ataggcagaa
    28561 tgtagaaaaa gttaccgtgt caaaggaaac acgccagaat tacaccaaag accgtaggac
    28621 aaaggttcag cagacccaga ctgtccagaa gaaccagcag accacagaga aaatccgtaa
    28681 tcttgtaacg aagaaaggac agaagaaaaa atgaaactga aacatatcgc tatcattgga
    28741 agtctgtttc ctattctctt ttctctggtg cttttctttg gggtgctgat tagtgcggac
    28801 agcgacgacg aaaacagcaa cttttcttct ggcattacgg gtatgaactt atccgcagaa
    28861 gttttgaaac atcagactat ggtagaaaaa tacgccagag aaaacggtat ctccgagtac
    28921 gtcaatgtac tactggctat cattcaagta gaaagtggcg gtacggcaga agatgttatg
    28981 cagagttcag aaagtcttgg tttaccgcct agttccttag atacggaaag ctcaatcaag
    29041 caggggtgta agtattttgc gtccctgctt tcttcctgca aaaatcaaga tatcgacgat
    29101 ttgaatgtag cgatacagtc ctataactat ggcggtggct atgtgggcta tgtggcagga
    29161 aacggaaaga aacacacttt taatcttgca gagagcttcg cccgtgagaa atcgggtgga
    29221 aagaaagtaa cctataccaa cccgatagcc gttgcgaaga acggaggctg gcggtatggc
    29281 tatggaaata tgttctatgt ggaattagtc aatcagtatt taactgttcc gcaggtatcg
    29341 ggagagctgg cacaaaaggt aatgaatgaa gcgttgaaat atcaagggtg gaaatatgtg
    29401 tttggtggtt cttctccaac cacttccttt gactgttcgg gactgacgca atggtgctat
    29461 ggaaaagctg gtatctcctt accgagaacg gcacaagccc agtatgacgc tacccaacat
    29521 cttccactct cgcaggcaaa ggctggcgat ttggtatttt tccattccac ctataacgct
    29581 ggttcgtatg taac
//
LOCUS       DAGQVA010000049        27987 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.049, whole genome shotgun sequence.
ACCESSION   DAGQVA010000049 DAGQVA010000000
VERSION     DAGQVA010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27987
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.049"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..210
                     /locus_tag="MIV85_002392"
     CDS             <1..210
                     /locus_tag="MIV85_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961724.1"
                     /translation="AMSELRSLIKQYDEMIHKDWNLATEEQKNRVEKLKCEVDNLKKS
                     DTGDDSKIWVEAIQNIAMKRGVNNG"
     gene            203..1612
                     /locus_tag="MIV85_002393"
     CDS             203..1612
                     /locus_tag="MIV85_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBY2961725.1"
                     /translation="MDKALLTLLDCYWDNPVWFAEDMLNFKADKWQSDVLMALAQTPK
                     VSIRSGQGVGKTGLESIATVWYLSTRPFPKVVATAPTRQQLYDVLWAEIAKWLSNSKV
                     EKLLEWTKTKVYMKGFEERWWATARTAVKPENMQGFHEDYMLFVVDEASGVADPIMEA
                     ILGTLSGAENKLLLCGNPTRTSGTFYDSHNRDRDLYKTFKVSSLDSPRTSKDNIEMLK
                     RKYHEGSDPWRVRVLGEFPKGESDSLISLEAVETSTIREVNISNDYILNIGADIARYG
                     DDETIIAPRIGGKVFDLLTYSKKDTMETVGNILRAVDKFKSMYHQINRVKIKTDDDGL
                     GAGVTDRLKEVIRQERLKYEIVPIQNGSSAIEKDKYYNKASEMWDNMREELDANLSGF
                     IQNKEAIIQLPNDDKLIKQLSNRKYTVDSKGKIQIESKKEMKKRIGESPDRADAVIYS
                     FAENNNTDLSLLKGGSVWG"
     gene            1603..3105
                     /locus_tag="MIV85_002394"
     CDS             1603..3105
                     /locus_tag="MIV85_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBY2961726.1"
                     /translation="MGIISYVKKLFKRPTGEIMRMSSGNIGVYKLDDSRVDYELAREL
                     YQNKNANYKLGSSFVRPIVNSTTGFMGVPHFQIEDEEAQYILDEFVLDNTSKMLKTHT
                     DSLKQGDCYIWITREERENPLYPDKKVRLIYNFISPEEVKEIILDPTTKEPIAYILES
                     QNEWTDLEENKRRAKVKQIITAESRIIEVEGDKIEGLEEGETPNVWGFIPIIHFKNEA
                     DETLKYGQSDIEPIEPLLKAYHDVMLHALKGSKMHSTPKLKLKLTDVASFLAHNFGVE
                     DPVKFAKEGGKINLDGHEILFLNKDEEAEFVEVKSAIGDAKELLKLLFYCIVDVSETP
                     EFIFGVHTPSALASVKEQMPIMVNKIRRKREQFTNSWQLLARMVLIMSSNSSGMKYSS
                     YDVTIGWDEVNPRDDKELAETLEKVCSALDKALEGGFISEESTVNFLAQYIDTMSNYI
                     SDDPEIVGEREKIIKTKMLKYRLDDSQGLDDESNEIDKEIDKIKDNNDNG"
     gene            3098..4105
                     /locus_tag="MIV85_002395"
     CDS             3098..4105
                     /locus_tag="MIV85_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961727.1"
                     /translation="MDKSTLELITVAGEYKKWALEARKKFIDLRLKQDDEIRTMYINI
                     TRNITKEIRKGNLSDFNKVRLKQILKQLTQEIKILNEQLVFNFDEYLNKNVETATSYS
                     KNILINAVETAQITKVTKAMIQKAFYDINIRTVEAYYTRVKDGLFLSDRIWSKCKKYR
                     EDMKVILQTAVTEGQDCVKTAKMLDKYVLKGKKTLVDEYPNMIKRIGNRVPQNISYEA
                     LRLARTEMTSAYGDGVLASAMINPATIGIQFMLSMAHPHTDICDEICGEDNFGLGKGV
                     YPINEAPAYPFHPHCLCIMLTVVQPLDILVGRLKNWIKNPMNDTPLEMWYQEVYGNLN
                     F"
     gene            4125..5459
                     /locus_tag="MIV85_002396"
     CDS             4125..5459
                     /locus_tag="MIV85_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961728.1"
                     /translation="MNVITGEMDSMNALISSIKPSDIPLAKDIDIEALKSIDDDPLEV
                     VVEIPATKSKRGWNYTAKSLKDIVDYTNENTLNGFLGHQKAENISTEFAPPVTHWIGA
                     EMKGDKAYFRGLIDADATNLKRWIRTKRIKEVSIFGYPKLKKSAKGEMNVIGYEPLSI
                     DWTPLHRPGMPTSIVGMEMSARGEQLDGTFEALRIDLREALKTKFSINDNNSYLYIQN
                     IRYDNNTVIYELEQNGLCKLYSIPFTIVENKINLGQEIEVIKKISYEAKGEMKGEENK
                     LEGKELIKNVKGLLQTGEISYSEVIQGIGLTKEIVTGEMEDVKSSLKAEKELREVKKV
                     LGIVGEMDTVEVAKKASKALENEKKEAWNCIVNKVIKDKVSGEIAQTLVKKMLNVEEG
                     SSEEVITGEIENILNDEFVKNTMSNMYKDNPTTTGLLNSSNNGSLTTKKNRI"
     gene            5475..5858
                     /locus_tag="MIV85_002397"
     CDS             5475..5858
                     /locus_tag="MIV85_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HBY2961729.1"
                     /translation="MAFKGQPTPSTITQITRAKISDGKSVRVILSEGESTKTQQFYLI
                     NGFFGVAMQDGEKGDEVTLQIEQAEYETDNIVTSEAFEAGKLIYWDNTAKKFTTTSAS
                     NRLVGRVTDGKDSNNVIWFILLPQQ"
     gene            5877..6914
                     /locus_tag="MIV85_002398"
     CDS             5877..6914
                     /locus_tag="MIV85_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HBY2961730.1"
                     /translation="MAFKVISQENLLEQKRKETLQEDIPFIVNGEMEYVTKKISNGEM
                     ETLELNKPLGEMMTFSSTSNLKELLRKVVLDVELGREQVQLLYKPIYDSIADSNLPQV
                     MDAKWALQGNCVFLEHIEGEEIKFGTINAENGPVARIQTYATGFEYTKEMKDFNQTFS
                     VEILNKSIGESYNALLNHIHLSPIINFNYKASNKTAFKGETNDPIWLGIWRTLTQAQK
                     DTVIAKRQGNILMASSADQIEIEMALNGGHLLNGSMYPSIKNISTVIYYDGWEVTVGK
                     KTYSYKGVTPGKGYLIRPKRGFKELIKRDLTTEVGNADLSKLVENQIVGHCYRGAFAA
                     VEENVQEISFR"
     gene            6954..7292
                     /locus_tag="MIV85_002399"
     CDS             6954..7292
                     /locus_tag="MIV85_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961731.1"
                     /translation="MTPARDLIEKLRLLLNDKDKKSFTDEELNLFLEEADCIYCAASQ
                     GWILKSLQYENTVGEMYEYKVGQETYKSSSIKDLVSVAYQNADKFKDMCTNKKEKGSF
                     MLGISTEFEI"
     gene            7289..7666
                     /locus_tag="MIV85_002400"
     CDS             7289..7666
                     /locus_tag="MIV85_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961732.1"
                     /translation="MINIDRRRKDIIRTININPTNITITSIKKTEIDGAFEETETEIK
                     CVVRIFNEKTAEKQISSEKQGTFSSIRTYGMLVSNDVILEVNSRDSLEFECIYGRMKI
                     VNIYPQIVKGELCGYQCSLERID"
     gene            7668..8078
                     /locus_tag="MIV85_002401"
     CDS             7668..8078
                     /locus_tag="MIV85_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961733.1"
                     /translation="MSAFTNAINDINRKKAGMLVLCMSASAMLEGEAKANARWTDRTS
                     HARQSLNAKTLSGGNNFIIRLSHGAEYGGILEEGSKPHVITPKSAQALYWRGASHPVK
                     SVQHPGTKATPIIKPTIDKNIGKIGNMIFRYWSD"
     gene            8079..8900
                     /locus_tag="MIV85_002402"
     CDS             8079..8900
                     /locus_tag="MIV85_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961734.1"
                     /translation="MRAGIRKALIDNIKELKGCYEPNVPNKDTKKPYMVVVQGQDNDH
                     GETIGFERSIEVWIYEGRTTFKKLDKLTKQVVEVLDMNTIVDESENEAFTCIYKGTSE
                     NDIVVEEWDAIARGIRFSVIALEDKEDTTNDRWVEALSRHTKDLLEIESYKDNWKKNF
                     IAPCALWRTTHIENKRINYHLIEITKTMKCHVVSKNKDEIVKLLETLETSLIIDKRVR
                     LREDKNMYLTLVSVVEDRESDMFTTGQLTAVFKMIGKIKREGPTMDKIYGNGNLK"
     gene            8913..9116
                     /locus_tag="MIV85_002403"
     CDS             8913..9116
                     /locus_tag="MIV85_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961735.1"
                     /translation="MAETNNKKINVSKQEEKYLKSDFIKNSEALGYGKMVVAGALFNC
                     KKEELTKAEFEKLIKDFLEREVK"
     gene            9118..10539
                     /locus_tag="MIV85_002404"
     CDS             9118..10539
                     /locus_tag="MIV85_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBY2961736.1"
                     /translation="MATGTWNEKERKEIPGFYNRFKTQAEKSTNTGLKGRLAMPIRAN
                     WGDVGKVVTIKNDLRQLKNLFGDDMNYSAFKLGKLALLGNVKELLLYRLVDGNQKKGT
                     LTLKDTTENSAKDVIKLETKYPTARNFNVTIKSNLVDSDKKDFIFFENTKQLFSSSIK
                     GTIDEIVLEINSNLDNEYVIATKVADSDTILANVVNQALEGGNDGCTSITNESYLKAL
                     EEFERYSFDSFVLDGVADEALQETTKAWVAKNKELGKDILLFLGGKKEDNIKQINDKS
                     KGFNDENIVNIGSSAYYEGIKYTPSEVAVYIGALAVSKGITGSICNAKTIFEEVEPRL
                     SQSEVKECLKSGTLILDFDDGDVIIVDDVNTFKKYVDDKNEAMGYISNIMFINTINKD
                     TSLKRKEFVGKIFNDSTGQTTVICALKKYFEELMSQGIISEFNVDIDTELQVTAKADE
                     FYWKWDAVKVDVMKKIYGTGYLG"
     gene            10555..10977
                     /locus_tag="MIV85_002405"
     CDS             10555..10977
                     /locus_tag="MIV85_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961737.1"
                     /translation="MGKYDENIIDAANVVDGSNARIIIDGEEEGYGTEFTAEVENDKK
                     TFRVIGCKWELNKASTQKGTFSLTVLKTTSKWIKKGFNKFEIITEIENPGLVGYERIR
                     YKNCMVDKIQLASIKSDENIEIQIDGTFEGFELLDEIA"
     gene            11054..11527
                     /locus_tag="MIV85_002406"
     CDS             11054..11527
                     /locus_tag="MIV85_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961738.1"
                     /translation="MENLDKEFLNEGIEEERELTKDEIAKQQEDNIIMKLTEDAILPE
                     KTIFVKRLDIPLTLRALTEKEISALQKKYTKVTKVRGRRESKLMEDEFNIALIEKATI
                     VPNFGDARLLNSMKVSNGVEFIRRKFLAGEIALISDEVLELSGFYEELSDGDIKN"
     gene            11708..12715
                     /locus_tag="MIV85_002407"
                     /pseudo
     CDS             11708..12715
                     /locus_tag="MIV85_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994354.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            12916..13794
                     /locus_tag="MIV85_002408"
     CDS             12916..13794
                     /locus_tag="MIV85_002408"
                     /inference="COORDINATES: protein motif:HMM:NF018205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBY2961739.1"
                     /translation="MKNLCKNCGKEFNGKVNQKCCSRKCSNELKFPKVITKCDYCGKK
                     IEKRPYEIERSKHHYCSSECRFKHQKLTLKGESNPNFKKANIDVKCSNCGKKINILKC
                     TIKNSDGTTKKNFYCSQICKAEHQKKILKKESNPNFKGGDINCSCDNCGKEINVKRHK
                     YKIHKYHYCSQDCKAKHQQVILVGKNNPFYKLDLSEEDRVKLRCIDGYNTWRRLVYER
                     DNYTCQCCSDDKGGNLEAHHLDGYNWCKEKRTNVNNGVTLCEICHNKFHNLYGFGNNK
                     KEQFEEFMKNNKNQAS"
     gene            14056..17340
                     /locus_tag="MIV85_002409"
                     /pseudo
     CDS             14056..17340
                     /locus_tag="MIV85_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994354.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            17420..18340
                     /locus_tag="MIV85_002410"
     CDS             17420..18340
                     /locus_tag="MIV85_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBY2961740.1"
                     /translation="MNFFKRKDDIKNFKLMYIKGHPHFNNELTCTMYIDKKLVSVYTL
                     QQVPISEIKLLDIEKVFIDNDMLIIESKKSVLYFKSNSKDKICNIINQNIADMQDKKT
                     DTILRNKNKIVKQGVMKMDYYNSVGVPNCRGEAISIIIDNHNACLVIESKLLKEEKMR
                     IKFSDLYSVNKYSEKEIAYNNKSVVGRAAIGTLFGPMGTIVGGLSGTGNKKSKTEKLF
                     ISIEYFSHGELREIIAEDSILNFHSQEFIDNIRRKINISKNNLENNKEKQIKSNDDAI
                     QQVKGLKELLDMGAITEEEFNKKKKELLNL"
     repeat_region   18598..19020
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=18598..18626
                     /rpt_unit_seq="attttatattaactatgtggtatgtaaat"
     gene            19313..19480
                     /locus_tag="MIV85_002411"
     CDS             19313..19480
                     /locus_tag="MIV85_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012159739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961741.1"
                     /translation="MPSKKIGRPTDNPKGSRITIRLDEESKNILEKYCEKEDIDKAEG
                     VRRGIKLLKDK"
     gene            19599..20417
                     /locus_tag="MIV85_002412"
     CDS             19599..20417
                     /locus_tag="MIV85_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBY2961742.1"
                     /translation="MNELMNFEGKDIEIFEYNGQVLFNPYDCGRCLELSDSAIRNHLS
                     KMNDTQAILLKNSAVLDKDIRKLNNAGEKFLTESGVYKLIFKSQKEEAEKFQDWISDE
                     VLPNIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLKELLDDAGFDNKSKLLT
                     AKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPAQMAVCEIIKKIDLEEN
                     EVKGVWETNGSWTGTVNKYTKSVIDKISKWIEENNRPTKIQGEKKNFHVVYKIE"
     gene            20471..20632
                     /locus_tag="MIV85_002413"
     CDS             20471..20632
                     /locus_tag="MIV85_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961743.1"
                     /translation="MCENLLDSIDIEKRKEECRIKLLKIRETDIDIYNKIESIVYKLS
                     EKKLEKNND"
     gene            21497..22168
                     /locus_tag="MIV85_002414"
     CDS             21497..22168
                     /locus_tag="MIV85_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBY2961744.1"
                     /translation="MVIDIYLKNEKEKIDFHFPVNPQDSLSIKKEKRFETVDIVNLGE
                     FDIKKEGEKIREISFKTFLPFQYDASYCRYSELKNPIEVVSMLEKWVDQAEPLRLIVT
                     GFGYNGLVTISSFSNTQVAGREEDRDIEITFRTYRELKIETLKKETKSNTKTDLKDNR
                     PNTQTKSKIYTVKASDTLYKIAKNLLGKGSRWPEIYNIPENKKVIGKNPNIIKKGQKL
                     VIPSK"
     gene            22165..23127
                     /locus_tag="MIV85_002415"
     CDS             22165..23127
                     /locus_tag="MIV85_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ"
                     /protein_id="HBY2961745.1"
                     /translation="MKIILNGKYDIANFNEGITLSEAIDGVAYKMDVSLIEPKQLKDI
                     NIKKGDKIVLIDIAYESKKEETIFDGVIWETRRSEKSKKLTLSCRERTVYMEESEEQY
                     SFKENTATQRIEYYCKQWNIPYYNLANTGKKLAKVIHKTNILDMIKKDLKETASKGGD
                     LFRVRMDNKLKLFKLGTNVNVYKLDSILEDANFTSSFNDAVTSVKVLGKSKDENTKAP
                     IIGTYKKDADKFGTLQKIKQDEKITNAKEAKKAAEAMFNSGEETISVDCVVDINRIRA
                     GDKVSLKNKEYYVIDVTHTLDSRPKMKLNIGTLEYIRRKFYTND"
     gene            23120..23485
                     /locus_tag="MIV85_002416"
     CDS             23120..23485
                     /locus_tag="MIV85_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961746.1"
                     /translation="MTDARFNGIARILKENMNKSVANGTFGMGCELAEITANGLKVSG
                     YKDEIQDYLVLENLTLKEDYFTFSDEALSGEYRHKHKIETPKELKPLRIGDNVLVAVM
                     GAEFVVIGRVVNAKPISSK"
     gene            23460..23918
                     /locus_tag="MIV85_002417"
     CDS             23460..23918
                     /locus_tag="MIV85_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBY2961747.1"
                     /translation="MPNLFPQSETFETVELKNNDENELDLKGSFLFDFEKGEFVKNAD
                     GTLKKCDKVQAYKQWCQKAILTPRYKKAAYTNIYGSEIKDLIASNLSQSAKELEITRL
                     IKETILVHPYTKEVGEFSFNWLENSRLVEYEFDVLTIDDENIVIDGNIKR"
     gene            23927..25060
                     /locus_tag="MIV85_002418"
     CDS             23927..25060
                     /locus_tag="MIV85_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBY2961748.1"
                     /translation="MERELPIPVFLTEDEDSVHERMLSNFQDVSTLEGDFIYDATRPT
                     AEQIAELKQLGLQNNLKIAFPQTSYGTYLEWLGECKGVFKNQPTKATGVITFTGVQGT
                     IITKGTIVTTIATDEKQSIEFELLETKTIGENETVDIKAESRIVGTIGNVSKGSISVL
                     LGSINGVKSVTNKDFKGGTDIEDEEHFRERVLVAEQEDKLSGASSDYIRWAKEVDGVG
                     YAYVVPEWNGAGTVKVLILDKNRKAATQELIDKVQEYIYPLNISEGENRDGKAPIGAL
                     VTVVTPDTLLINVKASFIFSNSFNEETVLNNLKTKIDKYLDKIDLGGTVSYNAIQAIV
                     GSMMLTDEGIQDFSNLTINDAKENIKLQDQVVGIGEIVNEVVG"
     gene            25057..25827
                     /locus_tag="MIV85_002419"
     CDS             25057..25827
                     /locus_tag="MIV85_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBY2961749.1"
                     /translation="MITSKKGKEMLLTLSPIYEQSLVMNSIYEAIGSEFDNLELLNKE
                     IELQLFPQTATWGLEFWENRVGLSTNIDEDIEARRRKVIAKLQMKYIVNPNRLATIIK
                     SYTGTDVYIKENIAPYTFKVTANVDDVINYEDFKYITNKTKPSHLHWMPSFALKFTDI
                     EKFEVKMINRIFIDFRGNISNFLDGMWLLNGSKNLSAYILYNEPISLNMKNKLFVKES
                     EVFTNLKVIIKKNLYYLNGLEMLNGNKLLNAELREEVL"
     gene            25830..26210
                     /locus_tag="MIV85_002420"
     CDS             25830..26210
                     /locus_tag="MIV85_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBY2961750.1"
                     /translation="MANAVTTDIARQKMCKARAGDITLPTIVSMAFGDGGIGNDGTII
                     APLSSDIALKNEVFRKDIENYVYPIPTTCRYSTTLLKNEAEGKNINEIGLIDSDGDLI
                     AIKSFGNKYKDSDMEMVFQIDDEF"
     gene            26315..26923
                     /locus_tag="MIV85_002421"
     CDS             26315..26923
                     /locus_tag="MIV85_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961751.1"
                     /translation="MLDNDKYLNNKIDTTKTELNTRIDTENEKQNIKIDQLIAGGSNV
                     ASTQIITIDDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENVVTNFKIIDDNSIE
                     IRSETRSELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDSISSIQLIDTSIS
                     ITDANDRFTSDKLDGVLEEIMVEISGQRTKGITIVNNLIDMI"
     gene            26937..27575
                     /locus_tag="MIV85_002422"
     CDS             26937..27575
                     /locus_tag="MIV85_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961752.1"
                     /translation="MTEKLTENASLGELMAALENVQTDFQTGKNNISSALGSPFIGTD
                     KFGTTKTKIETLKNVLVETINSKNVSATSSETFTNLIEKVNWIFQSIEIFSLKNRIQA
                     TTLNTPSIVYNEVSSIKGTLRFTGELKASKMRADYATAKIEILCGNRKEYFYVTDDTP
                     SASSSFVRFTKDIIVENGMDIKVQILLTSVGAGNLDGSYAARAEIEKLTILR"
     gene            27585..27797
                     /locus_tag="MIV85_002423"
     CDS             27585..27797
                     /locus_tag="MIV85_002423"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961753.1"
                     /translation="MKKQVYYNSLDEKEKIISENSNLYVIEIYETLNENYLVLSSSPI
                     QDEKLSYEELENELLIMTNELQGGLL"
     gene            27797..27979
                     /locus_tag="MIV85_002424"
     CDS             27797..27979
                     /locus_tag="MIV85_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961754.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKNSGVVEGIEPTA"
BASE COUNT        11595 a         2985 c         5371 g         8036 t
ORIGIN      
        1 gctatgagtg agttaaggag tttaattaaa cagtatgatg aaatgattca taaggattgg
       61 aatttagcta cagaggagca gaaaaataga gttgaaaagt taaaatgtga agttgataac
      121 ctaaagaaaa gtgatactgg agatgattca aaaatttggg ttgaagctat acaaaatatt
      181 gcaatgaaac gtggtgttaa caatggataa agctttattg acactattag attgttattg
      241 ggataatcct gtttggtttg cagaggatat gttaaatttt aaagctgaca agtggcaatc
      301 tgatgttctg atggctttag ctcaaacccc aaaagtatct attagaagtg gtcaaggagt
      361 aggtaaaact ggattagaaa gcattgcaac tgtatggtat ttaagcacta gaccttttcc
      421 gaaagtagtt gctacagctc caacacgaca acaattatat gacgtactat gggctgaaat
      481 agctaaatgg ctaagtaata gcaaggttga gaagctactt gagtggacta aaacaaaagt
      541 gtatatgaaa ggctttgaag aaagatggtg ggctacagct agaacagcag taaagcccga
      601 gaatatgcaa ggttttcatg aagattatat gttatttgtt gttgatgaag cttcgggagt
      661 tgctgacccc attatggaag ctatattggg aacattatca ggtgcagaaa ataagcttct
      721 tttatgcgga aacccaacta gaacaagtgg aacattttat gatagtcata atagggatag
      781 agatttatat aagacattta aagtatcttc tttagatagc cctagaacat caaaagataa
      841 tattgaaatg ctaaaaagaa agtaccatga aggttctgac ccttggcgtg ttagagttct
      901 tggagaattt ccaaaaggtg aaagtgattc tttaatatct ttagaagctg ttgaaacaag
      961 cacaataaga gaagtgaata tatctaatga ctatatatta aatataggtg cagatatagc
     1021 aagatatggt gacgatgaaa ctataatagc tccacgaata ggtggaaaag tgtttgattt
     1081 attaacttat tctaaaaaag acacaatgga aactgtagga aatatattaa gagcagttga
     1141 taaatttaaa agcatgtatc atcaaatcaa cagagtaaaa ataaaaacgg atgatgatgg
     1201 tttgggtgca ggtgttacag acagattaaa agaggttata agacaagaaa gactcaaata
     1261 tgaaattgta cctattcaaa atggttctag tgctatagaa aaagataaat actataataa
     1321 agcttctgaa atgtgggata acatgaggga ggaattagat gcaaatttaa gtggcttcat
     1381 acaaaataaa gaagctataa tacagcttcc taatgatgat aaacttatta agcaactatc
     1441 aaatagaaaa tatacagtag attcaaaagg gaaaatacaa atagaaagta aaaaggaaat
     1501 gaaaaaaaga attggagaat cacccgatag agctgatgca gtaatatatt cgtttgcaga
     1561 aaataacaat actgatttat ctttactgaa agggggtagt gtatggggat aatatcttat
     1621 gtaaaaaagc tatttaaaag acctactgga gaaattatgc gtatgtctag tggaaatata
     1681 ggcgtatata aattagatga ttctagagtt gattatgagt tagcaagaga attgtatcaa
     1741 aacaaaaatg ctaattataa attaggttct agttttgtta gaccaattgt caattcaaca
     1801 actggtttta tgggtgtacc tcattttcaa atagaagatg aagaagctca atatatatta
     1861 gatgaatttg ttttagataa cacatctaaa atgttaaaaa cacacacaga tagtttaaag
     1921 caaggtgatt gttatatttg gataactaga gaagaaagag aaaatccttt atatcctgat
     1981 aaaaaagtta gattaatata taacttcata tcacccgaag aagtgaaaga aataatatta
     2041 gaccctacga caaaagagcc tatagcttat atattagaaa gccaaaatga atggactgac
     2101 ttagaagaaa ataagagaag ggctaaggta aaacaaataa taactgctga aagtagaatt
     2161 attgaggttg aaggggataa gatagaaggt ttagaagaag gggaaactcc taatgtatgg
     2221 ggctttatac caataataca ttttaaaaat gaagctgatg aaacattgaa atatggtcaa
     2281 agtgatatag aaccaataga acctctttta aaagcttatc atgatgttat gttacatgcg
     2341 ttaaaaggta gcaaaatgca ctctactcca aaactaaagc tgaaattaac tgatgttgca
     2401 agtttcttag cacacaactt tggtgttgaa gacccagtta aatttgcaaa agagggtgga
     2461 aagataaatc ttgatggaca tgaaatacta ttcttaaata aagatgaaga agctgagttt
     2521 gtagaagtaa aatcagctat aggtgatgct aaggagcttt taaagcttct tttttattgc
     2581 atagtagatg tatctgaaac acccgagttt atatttggag tacatacacc tagtgcttta
     2641 gcttctgtaa aagaacaaat gcctattatg gtaaataaga taagaagaaa aagagaacaa
     2701 tttacaaata gctggcaatt acttgcaaga atggttttaa taatgagttc taattctagt
     2761 ggtatgaaat attcatctta tgatgtgact ataggttggg atgaagtaaa tccgcgtgat
     2821 gataaagaat tagctgaaac actagaaaag gtatgtagtg cattagataa agctttagaa
     2881 ggtggattta ttagcgaaga atcaacagta aactttttag ctcagtatat agatacaatg
     2941 agcaattata taagtgatga ccctgaaata gttggagaaa gagaaaagat aataaaaact
     3001 aaaatgttaa aatacagatt agatgattct caaggtttag atgatgagtc aaatgaaatt
     3061 gacaaggaaa tagataaaat aaaggataat aatgacaatg gataaaagta ctttggaatt
     3121 aataactgtt gcaggggagt acaagaaatg ggcattagaa gctagaaaaa aatttataga
     3181 tttaagactc aagcaagatg atgaaataag aacaatgtat attaacataa caagaaatat
     3241 tacaaaagaa ataagaaaag gaaatctttc agactttaac aaagttaggt taaaacagat
     3301 actaaaacaa ttaacacaag aaataaaaat attaaatgaa caactagtat ttaattttga
     3361 tgaatactta aataaaaatg ttgaaacagc tactagttac tctaaaaata ttttaattaa
     3421 tgcagttgag acagctcaaa taactaaagt aactaaagct atgatacaaa aagctttcta
     3481 tgatattaat ataagaactg tagaagctta ttatacaagg gttaaggatg gtttattttt
     3541 atctgataga atttggtcta agtgtaagaa gtacagagaa gatatgaaag ttatattaca
     3601 aacagcagta acagaaggtc aagactgtgt taaaacagct aagatgctag acaaatacgt
     3661 tttaaaaggt aagaaaactt tagttgacga atatccaaat atgataaaaa gaataggaaa
     3721 tagagtacct caaaatataa gttatgaagc tttaagattg gcaagaactg aaatgacatc
     3781 agcttatggt gatggggtct tagcttctgc aatgattaac cctgcaacca taggtattca
     3841 gtttatgttg tccatggcac atcctcatac agatatatgc gacgaaatat gtggagagga
     3901 taattttggt ttgggtaaag gtgtttatcc tataaatgaa gctcctgcat atccattcca
     3961 ccctcattgt ttgtgtatta tgcttactgt agttcaacca ttagatatat tagttggaag
     4021 gttgaaaaat tggattaaaa atcctatgaa tgatacacct cttgaaatgt ggtatcaaga
     4081 ggtgtatgga aatttgaatt tttaaattga aaggtggtga ttaaatgaat gtaataactg
     4141 gagaaatgga ctcaatgaat gcgttaatat ctagtataaa accttctgat attcctttag
     4201 ctaaagatat agacatagaa gctttaaaat ctatagatga tgaccctctt gaggtagttg
     4261 ttgagatacc agctacaaaa tctaaaaggg gatggaacta tactgctaaa agcttgaaag
     4321 atattgtaga ttacactaat gaaaatactc ttaatggttt tttaggacat caaaaagctg
     4381 aaaatatatc aactgaattt gcaccacctg taacgcattg gataggtgca gaaatgaaag
     4441 gggataaagc ttatttcaga ggactgattg atgctgatgc aacaaacttg aaaagatgga
     4501 ttagaactaa aaggataaaa gaagttagta tatttggtta tccaaaactt aaaaagagtg
     4561 ctaaaggcga aatgaatgtt ataggatatg agccactatc tattgattgg actcctttac
     4621 atagaccagg tatgccaaca agtattgtag gtatggaaat gagtgcgagg ggtgaacagc
     4681 tagatggaac ttttgaagct ttaagaatag atttaagaga agctttaaaa actaagtttt
     4741 ctattaatga taataattca tatctctata tacaaaatat aagatatgat aacaatactg
     4801 tcatatatga gttggagcaa aatggattat gtaagcttta tagtatacca tttactatag
     4861 ttgaaaataa aataaatcta ggtcaagaaa ttgaagtaat aaagaaaata agctatgaag
     4921 ctaaaggaga aatgaaagga gaggaaaaca aattggaagg aaaagagtta ataaaaaatg
     4981 tcaaaggatt gctgcaaact ggtgaaatat catattcaga ggtcatacaa ggaataggct
     5041 taactaagga aattgtgaca ggagagatgg aagatgtaaa aagttcatta aaagcagaaa
     5101 aagaattaag agaagtgaaa aaagtacttg gaatagtagg agagatggac acagttgaag
     5161 tggcaaaaaa ggcttcaaaa gctttagaaa atgagaaaaa ggaagcttgg aactgtatag
     5221 ttaataaagt aattaaagat aaagtgtcag gtgaaatagc tcaaacatta gttaagaaaa
     5281 tgttaaatgt tgaggaaggc tcaagtgaag aagtaataac aggagaaata gaaaatatat
     5341 taaatgatga gtttgtaaaa aatacaatgt ctaatatgta taaagataat ccaacaacaa
     5401 caggattatt aaactctagc aataatggaa gtttaacaac taagaaaaat agaatataaa
     5461 ggagtgatgt ttatatggca tttaaaggtc aaccaacgcc aagcacaata acacagataa
     5521 caagagcaaa aataagtgat gggaaatctg taagagttat tctttcagaa ggtgaaagca
     5581 ctaaaacaca acaattttat cttataaatg gattctttgg agtcgctatg caagacggag
     5641 aaaaaggcga tgaagttact ttgcaaatag agcaagctga atacgaaacg gataatattg
     5701 ttacatcaga agcttttgag gcagggaaat tgatttattg ggataataca gctaagaaat
     5761 ttactactac atctgcaagt aataggctag ttggtagagt aacagatggg aaagacagta
     5821 ataatgtaat ttggtttata ttattacctc aacaatagaa aaggagtgat aaatatatgg
     5881 catttaaagt aattagtcag gaaaatttgc tggaacaaaa aagaaaagaa actttacaag
     5941 aagatatacc atttatagta aatggtgaaa tggaatatgt aacaaagaaa atatcaaatg
     6001 gagaaatgga aaccttggag ttaaataagc cacttggtga aatgatgact tttagctcga
     6061 cttcaaattt aaaagagtta ttaagaaaag ttgtattaga tgttgaacta ggcagagagc
     6121 aagtacaact attatataaa ccaatctatg acagtatagc agattctaat ttaccacaag
     6181 ttatggatgc taagtgggct ttacaaggta actgtgtatt cctagagcat atagaaggtg
     6241 aagaaattaa attcggtaca ataaatgcag aaaatggtcc agttgcaagg atacaaactt
     6301 atgcaactgg ttttgagtat acaaaagaaa tgaaggattt taaccaaaca tttagtgttg
     6361 aaatattaaa taaatcaatt ggtgagagtt acaatgcctt gttaaaccac atacatctaa
     6421 gcccaataat aaattttaat tataaagctt ctaataagac agcttttaaa ggtgaaacta
     6481 atgacccaat atggctagga atttggagaa cattaacaca agcacaaaaa gatacagtta
     6541 tagcaaaaag acaaggtaat atattaatgg cttctagtgc tgaccaaatt gaaatagaaa
     6601 tggcgttaaa tggaggacat ttattaaacg gaagcatgta tccatctata aaaaatatat
     6661 caacagtaat ttattatgat gggtgggagg ttactgttgg taaaaaaaca tattcttaca
     6721 aaggtgttac accaggcaaa ggatatttga taagacctaa gcgaggattt aaagagttaa
     6781 taaagagaga tttaacaaca gaggttggaa atgctgattt aagtaagtta gtagaaaatc
     6841 aaattgtagg tcattgttat agaggtgctt ttgcagcagt agaagaaaat gtacaagaaa
     6901 taagttttag ataaaacact cataagagtg ttatttttat gaggtgataa tatatgacac
     6961 cagctagaga tttaatagaa aaattaagac tattattaaa tgataaagat aaaaaatcat
     7021 ttacagatga agaattaaac ttgtttttag aggaagcaga ctgtatttac tgtgcagctt
     7081 ctcaaggatg gatattaaaa tctttacaat atgaaaatac agtaggggaa atgtatgagt
     7141 ataaagtggg tcaagaaaca tataaaagct ctagtataaa agacctagta tctgtagctt
     7201 atcaaaatgc agataaattt aaggatatgt gtactaacaa aaaagaaaag ggaagtttta
     7261 tgttaggaat tagcacagaa tttgaaatat gataaatatt gatagaagaa gaaaagatat
     7321 aataagaact attaatataa accccactaa tattactata actagtatta aaaaaaccga
     7381 aatagatgga gcttttgaag aaactgaaac agaaataaaa tgtgttgtta gaatatttaa
     7441 cgaaaagaca gcagagaagc aaatatcaag tgaaaagcaa ggtacattta gttctattag
     7501 aacatatgga atgttagtaa gtaatgatgt tatcttagag gttaacagta gagattcttt
     7561 agagtttgag tgcatatatg ggagaatgaa aatagttaat atatatcctc aaattgtaaa
     7621 aggagaactt tgtggatatc aatgttcact tgaaaggatt gattaaaatg agtgctttca
     7681 caaatgcaat aaatgatata aatagaaaaa aagcaggtat gcttgtactt tgtatgagtg
     7741 caagtgcaat gctagaaggt gaagctaaag caaatgcacg ttggacagat agaacatcac
     7801 atgcaagaca aagtttaaat gctaaaacac ttagtggagg aaataatttt atcattagat
     7861 tatctcatgg tgcagaatat ggagggatac ttgaagaagg ctcaaaacca catgttatta
     7921 ctccaaaatc agctcaagcc ctatactgga gaggtgcttc acatcctgta aaatcagttc
     7981 aacatcctgg tacaaaagca acgcctatta taaaaccaac tattgataaa aatataggta
     8041 aaataggtaa tatgattttt aggtattgga gtgattaaat gagggcagga ataagaaaag
     8101 ccttaataga taatataaaa gaattgaaag gttgttatga acctaatgta ccaaacaaag
     8161 atactaaaaa accttatatg gtagttgtac aagggcaaga caatgaccat ggagaaacaa
     8221 taggttttga aagaagtata gaagtatgga tttatgaagg tagaacaaca ttcaagaaat
     8281 tagataaatt aactaaacaa gttgttgaag tcttagatat gaatactata gttgatgaat
     8341 ctgaaaacga agcttttact tgcatttata aaggtacaag tgaaaatgat attgttgttg
     8401 aggaatggga tgctatagca agaggtataa ggtttagtgt aatagcttta gaagataaag
     8461 aagatacaac taatgatagg tgggtagaag ctctatctag gcacacaaag gatttattag
     8521 aaatagagag ttataaagat aattggaaga aaaactttat agctccatgt gcattatggc
     8581 gaactacaca tattgaaaat aaaagaatta actatcattt aattgagatt actaaaacta
     8641 tgaaatgtca tgttgtaagt aaaaataaag atgaaatagt taagcttctt gaaacattag
     8701 aaacaagctt aataatagat aaaagagtaa gacttagaga agataagaat atgtatttaa
     8761 ctcttgttag cgtagttgag gatagggaat cagatatgtt tacaactgga caattaacag
     8821 ctgtgtttaa aatgatagga aagataaaaa gagaaggtcc tactatggat aaaatttatg
     8881 gtaatggaaa tttaaaatag gaggtgcaag aattggctga aacaaataat aaaaagatta
     8941 atgtaagtaa gcaagaagaa aaatatttga aaagtgattt tataaaaaat agcgaagcac
     9001 ttggctacgg aaaaatggta gttgcaggtg ctttatttaa ttgtaagaaa gaagaactta
     9061 caaaagcaga atttgagaaa ttaataaaag atttcttaga aagagaggtg aaataaaatg
     9121 gcaactggta catggaatga aaaagaaaga aaagagatac ctggttttta taacaggttc
     9181 aagactcaag cagaaaaatc tacaaacaca ggattaaagg gtagattagc aatgcctatt
     9241 agggctaatt ggggagacgt tggcaaggtt gtaacaataa aaaatgattt aagacagctt
     9301 aaaaatctat ttggggatga tatgaattat tcagctttca agctaggcaa attggctctg
     9361 ttagggaatg taaaagagtt attactatat agacttgtag atggaaatca aaagaagggt
     9421 acattaacac taaaagatac tacagaaaat agtgcaaaag atgtaattaa gttagaaact
     9481 aagtatccaa cagctagaaa ctttaatgta acaataaaat ccaatttagt agattcagat
     9541 aaaaaggact ttatattctt tgaaaatact aaacagttat ttagttcaag tattaaaggc
     9601 actatagatg aaatagtact agaaataaac tcaaatttag ataatgagta tgtaattgca
     9661 actaaagtag ctgatagcga tacaattcta gcaaatgtag taaatcaagc tttagagggt
     9721 gggaatgatg gttgcacatc tattactaat gagtcttatc taaaagcact agaagaattt
     9781 gaaagatata gttttgactc ttttgtactt gatggtgtgg ctgatgaagc attgcaggaa
     9841 actacaaaag cttgggtagc taaaaataaa gaattaggaa aagatatact actttttcta
     9901 ggtgggaaaa aagaggataa tataaaacag ataaatgata aatcaaaagg tttcaatgat
     9961 gaaaatatag ttaacattgg aagttcagct tattatgagg gaataaaata tacacctagt
    10021 gaagtagctg tttatatagg agcattagca gtaagcaaag gtataacagg tagtatatgt
    10081 aatgctaaga ctatatttga agaagtagaa ccaaggttaa gtcaaagtga agtcaaagag
    10141 tgtttgaagt caggtacact aatacttgat tttgatgatg gagatgtgat tatagttgat
    10201 gatgtgaaca cctttaagaa gtatgtagat gataagaatg aggcaatggg atatatctct
    10261 aatattatgt ttattaatac tataaataaa gatacttcat tgaagcgaaa agaatttgta
    10321 ggtaagatat tcaacgattc aacagggcag acaactgtta tatgtgcatt aaagaaatat
    10381 tttgaagaat taatgagtca aggtattata tctgaattta atgttgatat agatacagag
    10441 cttcaagtaa ctgccaaagc agatgaattt tattggaagt gggatgctgt gaaagttgat
    10501 gtcatgaaaa aaatatatgg tactggatat ctaggataaa ggaggttata aagtatggga
    10561 aaatatgatg aaaatattat agatgctgca aatgttgttg atggttcaaa tgctagaata
    10621 ataattgatg gagaagaaga aggatatgga acagaattta cagctgaggt agaaaatgat
    10681 aaaaagactt ttagagtaat tggttgtaaa tgggaactta acaaggcatc cactcaaaaa
    10741 ggaacttttt ccttgactgt acttaaaact acatctaagt ggattaaaaa aggatttaat
    10801 aaatttgaaa taattacaga aatagaaaat cctggattag ttggatatga aagaattaga
    10861 tataaaaatt gtatggtaga taaaatacaa ctagcaagca taaaatctga tgaaaatata
    10921 gaaatacaaa tagatggaac ttttgaagga tttgagttgt tagatgaaat agcataataa
    10981 ataaatttaa gctacacgta attaatttta tgtgtagctt tttataaaac tataaaattg
    11041 gaggaagtta aaaatggaaa acttagataa agaattttta aatgaaggaa tagaagaaga
    11101 aagagagctt actaaagatg aaatagcaaa gcagcaagaa gataatataa ttatgaaatt
    11161 gacagaggat gctatattac ctgaaaaaac tatttttgta aaaaggttag atataccact
    11221 tacgctgagg gctttaacag aaaaagagat aagtgcattg cagaaaaaat atacaaaagt
    11281 tactaaggta agaggtagaa gagaaagtaa actaatggaa gatgaattta atatagctct
    11341 aatagaaaaa gctacaatag ttcctaattt tggtgatgca agacttctta attctatgaa
    11401 ggtatcaaat ggagtggaat ttataagaag aaagttttta gcaggtgaaa ttgcattaat
    11461 tagtgatgaa gtactagaat tgtctggatt ttatgaagaa ttaagtgatg gtgatataaa
    11521 aaactaataa agagaggtgg gaagattact attttatata acgcatatgt taaacatagt
    11581 gttcttccag aagattttct aaaaagagag aaaacacctc aacagcttct tagagttttt
    11641 actcaatatg aaatagaaca agaaaataaa gctatgaaaa ataaatgaaa tttaaactga
    11701 aagtgaggtg agagaaatag ctaaaaaaga aatgtatcat attgatgtcg ttattgatgt
    11761 tacaggagat gaacaaacta agagtaaatt aagtgctatg gaaagataca cgaaacagac
    11821 agaaaagaga atgaaagcac tgaataggat aaaagctaat ccaattatac aagctcaaga
    11881 taaaacatct agtgttgtaa atagaattag caacaactta aaaagagtgg gtagaactat
    11941 atctacaacc ataaacgcaa aagatagagc atctagcgtt gtaaatagag ttaaaaacaa
    12001 agtaaatagc ttacttacaa gtcgacaaag agaagtttta ttaaaggcta gagacaaagc
    12061 tagtcaagtc gtagataaag taaaggcaaa ggtacaaaat ctgactgcgg ctacaataat
    12121 tagtttaaat atgaaagctg acccagcgct aagagttatt tctcaaacta gaagtaagtt
    12181 aggagagctc aaaaacaaca caataataaa tattaaagca aaaggtgaag aagcattaaa
    12241 tactatttct cgtactaaga gtaaattaca agagttttct aatagaactt accaagcaat
    12301 tgtaaaacta aaagatgaag ctagtccaac tttgagtggt attggaagta aaatagattc
    12361 atttataagt ggagcaataa gtaaattcgc tcaattaaca acagcaatta ctgttgcact
    12421 tggaggtata ggggttggtt cttcgataaa aacttttgct aatttcgagc aaggaatgaa
    12481 aaacgttcaa gctgtcacag gagcaagcgg aaaagaaatg gaagctttaa ctgtaaaagc
    12541 tagaaatctt gggaaaacaa ctgcatattc agctagagaa gtgagcgatg ccatgtatta
    12601 tgcgggtatg gcaggttgga aaactaatca gattatcgaa ggtatgccag gcatcttgaa
    12661 tttagcagca acaggaggaa cagatttggc actaacgagt gacattgtga ctgaaataca
    12721 ttggtcggtt atggagaaat ctatagcata aaacattcgg caaaatcggt agattctaag
    12781 ttctaattga taatttatag tataatattt atagggatag attaggaagt cgcgagccta
    12841 attgaaaagg agtatttccg agacttcttc ccttttataa attaagtagg aaaaatactg
    12901 cggaggtatt taaaaatgaa aaatctatgt aaaaattgtg ggaaagaatt taatggaaag
    12961 gttaatcaga agtgttgttc aagaaaatgt tccaatgaat taaagtttcc aaaagtaata
    13021 acaaaatgtg attattgtgg caaaaaaata gaaaaaagac catatgagat agaaaggtca
    13081 aagcaccatt attgttcatc tgaatgcagg tttaaacacc aaaagctaac attaaaagga
    13141 gaaagtaatc ctaactttaa aaaagctaat attgatgtta agtgtagtaa ttgtggaaaa
    13201 aaaattaata tacttaaatg tactattaaa aattctgatg gtacaaccaa aaaaaacttt
    13261 tattgttctc agatatgtaa agcagaacat caaaagaaaa ttctaaaaaa agaaagcaat
    13321 ccaaatttta aaggtggaga tattaattgt agctgtgata attgtggaaa agaaataaat
    13381 gttaagagac ataaatataa aattcataaa tatcattact gttcacaaga ttgtaaagct
    13441 aaacatcaac aagtaatttt agtagggaaa aataatccat tttacaaatt ggatttaagt
    13501 gaagaagata gagtgaaatt aagatgcata gatgggtata acacatggag aagacttgta
    13561 tatgaaaggg ataattacac ttgtcaatgt tgtagtgatg ataaaggtgg aaatttagaa
    13621 gcccatcatt tagatggtta taattggtgc aaagagaaaa gaactaatgt aaataatgga
    13681 gtaactttat gtgagatatg ccataataag tttcacaatt tatatggatt tggaaataat
    13741 aagaaagaac aatttgaaga atttatgaaa aataacaaga atcaagcatc ttaaatttta
    13801 agatgctttt tattatacta aagtttttta ataagaatat gaaagtaccg aggtaatatt
    13861 acagattgcg aaaggttgta atacaccgta gagcgtagga gttgaataaa tataatactc
    13921 ccaagagtgc cgaacaccct aacgaattag acgagggtga aaatgtacgc caaactaggc
    13981 ttgaaaagac aagccgatga aaatgaggga aacttctaga gtctaagata aaaagcttag
    14041 agataataac tattggatgg actaactgcg ttaggaatga ctgctaaaga tactggtcaa
    14101 ttcgttgata ttatggctgc aactataaca aattctaata caaatgttga gttatttggg
    14161 gaaacactta aatttattgg gtctctagga ggttctttgg gtgtacctat gagggacgtg
    14221 gctctagcaa caggtttgat ggcaagtagt gctatcaagg gaagccaagc aggaacttct
    14281 ctaagaatgg gtcttttaag acttataaat gagcctaaga gagctgcaac agctatgaga
    14341 aaatatggaa tagaaatgaa aacaactaaa agtggaagtt tagatttagc agcaacaata
    14401 gatgaactta gaaataagct tggtaagctt agtgacacga agaaagtagg agctttagga
    14461 gatatagtag gagctaatgc ttcaagtggt tgggctgcaa tagtaaatgc tagtgaaagt
    14521 gactataata aactaaaaaa agccatagct gaaagcgagg aagaagctaa aagaatagct
    14581 gacatgaaga tggattcctt gaatgggcag ttcgctaaat taaaaaatac tataaatgat
    14641 gtaaaaatta gtataggaga aaaattaggt ccagtaacaa gaaactttat ggaaaatata
    14701 attagtagta tgcctaaagt tggtgattca attgtaaatt ttgtgagtaa ttttataaat
    14761 aactttgata aaataaaaaa tgttttacaa ggtgtggctt ctgttgttgg tggtgttatt
    14821 gctggattta tggcttttaa agctttaaca gtaatttcta gcgtaataag tataattaca
    14881 aagatagcta cagcatcaac gctaattgga ggaatagttg gagttcttgg acccgttggt
    14941 gcaatagttt tagctatagg cgtattagca ggagcatttt tatttgctta tcaaaaatct
    15001 gaaactttta ggtatggtat taaaaacata ggtaaatcaa tatctaattt tttaaaacct
    15061 ttaaatcctt ttatagaaca aataaaaggt aaatttaaag aacttataaa tgcgttaaaa
    15121 cctttgtttg cagttttttc taaattaggc tcaatgattg taagtgcttt atcaccagtt
    15181 atacaatttt tggcgacagt tttcataata aaatttatgt attcatttaa tgtaattgtt
    15241 aacaaggtaa aagctatagt aaatacaaca acagtagtag taaatggttt aatagagata
    15301 tttaaaggga tagctgatgt agttaaaggt tttataaata gagatatgag ccaagtagtc
    15361 aacgggctta aatctatttt taaagggatt atagatattg ttaagtcatt gtggagtggg
    15421 ttagtagatt ttgtgacatc accaattcaa gctgtagtcg atattttgga tactaagttt
    15481 ggcaaaaaag tggaaggcat aaagaaaaaa tggaatgaat taaaagactt tttaaaaaat
    15541 cctactaaat cagctccaaa agttcagcct gttaatttat ctagcgagaa agcatcaagc
    15601 gaactgcaaa cttcatcaaa tggagcaaaa gaatatataa gctcattagg tcaaaaaata
    15661 ggagaaggta ttgggaaaat taaagagaaa tttggagaac tcaaaacatc tgcgacagaa
    15721 gtatttaata atatagtaac ttttataggt ggcaaagcaa cagaattaaa agataaacta
    15781 ttagaaggca taaaacctgc tatagataca tttaaacaag ctttttctaa tcttaaagaa
    15841 acttttgggg gctctttgga cagtataaaa gaagcttttg gaggtttaaa aactgtattt
    15901 gatgaaaata ttaaaacgcc tttcgaaaat ttaaaacaaa aagttttaga aacaaaagaa
    15961 agtttaaaac cagtttttga taacttaaaa tctagctttg cagaactagg aaaagctctt
    16021 gaaccaataa aagaagcatt tagtggaata aaagatttct tttcaaattt gtttaagcca
    16081 atcaaagatg atggagcaac taagacaact aaaactaata tggatgagtt aaaacaatca
    16141 acacaaagcg taggaacgtc tttcaaagag ctagggaatg cttttaatca attaaaagaa
    16201 gcagcaaaac cttttataga ctatttaaaa cagataaaag attctttaac atctactctg
    16261 ggagatatag ggggaggatt actcaaaggt gtagcaactt ctatagtttt agttataact
    16321 tctgttatta atgcaattgc atctattata aatgctgtag caggggctgt aaaaggtgta
    16381 attgacatag taaaaggaat atttgaagtt ataggaggga tagttactgg tgatggtgaa
    16441 aaaataaaac aaggtttctc tgatattttc aaaggtattg gggaagtggt taagtcttta
    16501 tgggaaggta taaaaggagt tttgggagca ccacttaaag ctgttgtaga ttttgtaagt
    16561 aatggatttt cagaaaaagt agggcaagta aaacaatggt ggtctgattt aaaaactaat
    16621 gtaggccaaa aaataagcgg atttgttagt tttgtaagca atggttttca acaaaaagtt
    16681 caacaagttg gaatgtggtg gcaaggactt aaagtaaatt tatctggcaa aataagtgga
    16741 tttgtaagtc ttgtagaaaa cggatttaaa agtaaagtgg attcaattaa atctgcttgg
    16801 gattctctta aaaagaaact ttctaccaaa ataactggtt ttgtaagtat agtaaaaact
    16861 ggagtaagca atatactaga ccattttgca gatggtggtg ttgcaagtaa accatccata
    16921 tgtggagaag caggtcccga aatggttatt cctctttcta atagtaaaag aagtagagca
    16981 ttaagtttat atgaacaagc aggacagata cttggaacta aagcaagtaa taatgttatt
    17041 ccaatttctc agaaattagg aaatagcttt aattctacaa gtagtattca aaagagtact
    17101 tctaatatta ttgataacat taggcaattt cctgctagac aagaagaatt taataataca
    17161 gaaaatagaa tttatcaaga agctcaacta caaaacataa tttctagtgg aagtaatgcg
    17221 attaatgttg gtggaatatc tataaatatt caagacaaca ataacaaaga agaaatgata
    17281 caagaaatat tgtctcaagt ggaaagtgag ctaagagaag cattacaaga tattggataa
    17341 tgtcgaatta ttgttaaaaa aatcctcctt atagatgtta taataacatt atagactatt
    17401 gatttatgag gggattaaaa tgaatttttt taaacgaaaa gatgacataa agaattttaa
    17461 gcttatgtat ataaaagggc acccacattt taacaatgaa cttacatgta ctatgtatat
    17521 agataaaaaa ctagtatctg tatatacatt gcaacaagta cctattagtg aaataaaact
    17581 tttagatata gagaaagtct ttattgataa tgatatgcta attatagaaa gcaaaaaaag
    17641 tgtattgtat tttaaaagta actcaaaaga taaaatatgc aatataatta atcaaaatat
    17701 agcagatatg caagataaaa agacagatac tatattaaga aataaaaata aaatagttaa
    17761 acaaggggta atgaagatgg attactataa ttctgttgga gttcctaatt gtaggggtga
    17821 agcaataagt ataattattg acaaccataa tgcatgttta gttattgaga gcaaactttt
    17881 aaaagaagaa aaaatgcgta ttaaattttc tgatttatat agtgtaaata agtatagtga
    17941 gaaagaaata gcatataata ataagtctgt tgttggaaga gcagctatag gaactttatt
    18001 tggtcctatg ggaacaattg ttggtgggtt gtcaggaact ggaaataaaa aaagtaaaac
    18061 tgaaaagttg tttataagta ttgaatattt ttctcatgga gaattaaggg aaataatagc
    18121 tgaagattca atacttaatt ttcatagcca agaattcatt gataatataa ggagaaaaat
    18181 aaatataagt aagaataatt tagaaaataa taaagaaaaa caaataaaat caaatgatga
    18241 tgcaatacaa caagtgaaag ggttaaaaga gttattagac atgggagcaa taacagagga
    18301 agaatttaat aagaagaaaa aagaattatt gaatttataa caagagaaaa taaataagta
    18361 taaacataca aagcacttgg atattctgtt gtttcaagtg ctttatatgt taaaaaatgg
    18421 tataatatag gtaaggcttt agcagtgttc gattttttga aatattgctt gtagtgattg
    18481 aaattactat attacaggta tgctttatga aatgccaaaa aacactactg gtcgctcact
    18541 gcaaatttaa gaaagctata tatatgtaag tattggaaat actaaattta ttttgggatt
    18601 ttatattaac tatgtggtat gtaaatgcaa aagctgttat tgcaaaagtt atattactta
    18661 gcagatttta tattaactat gtggtatgta aatcgttaga attaatcaaa ttcattttca
    18721 actcactaaa ttttatatta actatgtggt atgtaaataa gcagatgatg cttgtgagaa
    18781 aatagttctt aatgtatttt atattaacta tgtggtatgt aaataaggct ttagagactg
    18841 taagaagtat atttgctcaa gattttatat taactatgtg gtatgtaaat gctaaaacat
    18901 tacttgataa aaacaaaatt acaggatttt atattaactg agtggtatgt aaatttatca
    18961 atcttagtat tagatgtatc tttgtataat tgttttatat taactatgtg gaaaaaaata
    19021 aataaaaaaa gaaagcactt acttttggta ggtgcttttg ttttgctcaa attacctaat
    19081 tctaaaatcg gtttaactga ctttagaacg tacaaatagt aaaattaact aacttagaag
    19141 ttgttaagta caacttttga gaattataca atataaaaat gaactaaagt gattgatttt
    19201 actcaagttg gtcggttgag tgaaataatt agaaaaaatt ggaataagtt attgactttt
    19261 gtctgccaaa actatataat ataattaagg cagacaaaag tgaggtgaag atatgccaag
    19321 taaaaaaata ggtagaccta cagataatcc taaaggcagt agaataacta taagattgga
    19381 tgaagaatct aaaaatattc tagaaaaata ctgtgaaaaa gaagatatag acaaagccga
    19441 aggagttaga agaggtataa aactactaaa agacaaataa aaagtagccc aaccgccgac
    19501 caaagcaaaa tggactactt acaccagaag ttaccttcta tgaaatattt tatcatagta
    19561 aggtacttct tacaatcaaa tttaaggagg aatttactat gaatgaatta atgaattttg
    19621 aaggaaaaga tatagaaata tttgaatata atgggcaagt tttatttaat ccatacgact
    19681 gtggaagatg tttagagcta agtgatagtg caataagaaa tcatttatct aaaatgaatg
    19741 atactcaagc tatcttgtta aaaaattcag ctgtcctaga taaggacatc cgaaaactga
    19801 ataatgcagg tgaaaagttc ttaactgaga gtggggtata caagttaata tttaaatctc
    19861 agaaagaaga agcagagaag ttccaagact ggataagcga tgaagtactt ccaaacattc
    19921 gacaaacagg tgcatacata actaacaatg ccaaccccga aaaactaaga gaaaaagcaa
    19981 gcgagattga aaaactacaa ctagcttata acagtacatc tatgttaaaa gaactattag
    20041 atgatgcagg atttgacaac aaatcaaaac tattaacagc taaaacatta tataaaaagg
    20101 caggtattga tttaccgatt gagataaacg aagaagaaca ttattttgat acaaaacaaa
    20161 tagcgtctaa actgaaaata tattctaaga gtaataaacc agctcagatg gctgtttgtg
    20221 aaattattaa aaagattgat ttagaagaaa atgaagtaaa aggagtttgg gaaacaaatg
    20281 gttcttggac tggtactgta aataaatata caaagagtgt aatagacaag attagcaaat
    20341 ggatagagga aaataataga cctactaaga tacaaggtga gaagaagaat ttccatgttg
    20401 tatataagat tgagtagatt tatcagttgt attaaataat atattttatt ttattttggg
    20461 gggtaataca atgtgtgaga atttacttga tagtatagat attgaaaaga gaaaagaaga
    20521 atgtagaatt aaacttttga aaataagaga aacagatata gatatatata ataagataga
    20581 aagtatagta tataaacttt ctgagaaaaa attagagaaa aataatgatt aaatagacat
    20641 ataaagcact tgaatatttc actgtttcaa gtgctttatg tagtaaaaaa tgatataata
    20701 taggtaggaa attatattaa ctaagtggta tgtaaaggga aaaaccgttg gggatgctat
    20761 ggaggcactt gcagatttta tattaactaa gtggtatgta aagtcttctt ttgagataaa
    20821 cagtaaagta atagtaaata attttatact aactatgtgg acttaaaatt aaaaatatca
    20881 aagaacactt acttaaatag taggtgtttt tttattgaaa gaaggcgatt ataatgcaaa
    20941 aagtaataaa taggtaaaat atgtaaaagt tatatgctat aataattgta gcaaggaaaa
    21001 taataattga aaagtgctaa gagtggctat ttccatatta aacgccaaat tccataacgg
    21061 aaggaggtgg aaccatatgg tgataaattt tttattgagt atactagctg gtgttatatc
    21121 agctttcatg tatgataaaa taaaaaacca ctcaaacgcc aataagagtg gtttaaaaaa
    21181 gtaattcttt aaatcgattt tgatggaaat agctactctt gtataaagta aattattatt
    21241 tccttgcttt tattatacca caaattagaa aaaatattac ttataatatt ttttatagtc
    21301 aataaaaaga tgaaattttt tatacaaaat aatgatgaat ctaaattaat gaataaattt
    21361 aattgtaaaa cggtaaatac agtaagcact tacaaacatg taggtgtttt tttatacaaa
    21421 aaatcaaaga aggtgaatat atggtaagga gactgcggtg taatgtcaaa aaacatttta
    21481 gaaaggaagt gataaattgg taatagacat atatctaaaa aatgaaaaag aaaaaataga
    21541 tttccatttt ccagtaaacc cacaagattc tctatctata aaaaaagaaa aaaggtttga
    21601 aactgtagat atagtaaact taggtgaatt tgacattaaa aaagaagggg agaagataag
    21661 agaaatatca tttaaaacat ttctaccttt tcaatatgac gcttcttatt gcagatacag
    21721 tgagttaaaa aatccaatcg aagtagtgtc aatgcttgaa aaatgggtag accaagctga
    21781 accattaaga ttaatagtaa ctggctttgg ctacaatgga ttagtcacaa tatctagttt
    21841 tagcaatact caagtggcag gaagagaaga agatagagac attgagataa catttagaac
    21901 ttacagagaa ctgaagatag agacattaaa aaaagaaaca aaaagtaata ctaaaacaga
    21961 tttaaaagat aatagaccta atacccaaac taaatctaaa atatatactg ttaaagcaag
    22021 tgatacatta tataagatag ctaaaaatct tttaggtaag ggttcaaggt ggccagagat
    22081 ttataatata cctgagaata aaaaagtcat tggcaaaaat ccaaacataa ttaaaaaagg
    22141 gcaaaagttg gtgatacctt ctaaatgaaa ataatattaa atggaaaata tgatattgca
    22201 aattttaacg agggaataac attaagtgaa gctatagacg gagttgcata caagatggat
    22261 gtatctttaa tagaacctaa acaacttaaa gatataaata ttaaaaaagg tgataagata
    22321 gttctaattg acattgcata tgagagtaaa aaagaagaga cgatatttga tggggtcata
    22381 tgggaaacta ggagaagtga aaagagtaag aaactgacac tatcttgtag agaaagaaca
    22441 gtttacatgg aagaatcaga ggaacaatat tcgtttaaag aaaatacagc aacacagagg
    22501 attgaatact attgtaagca atggaatata ccatattaca acttagctaa cacagggaag
    22561 aaacttgcta aagtaataca taagactaat atcttagata tgataaaaaa ggacttaaaa
    22621 gaaacagcaa gtaagggtgg agacttattt agggtaagga tggataacaa attaaaacta
    22681 ttcaaactag gaactaatgt aaatgtatat aaattagata gtatattaga agatgcgaac
    22741 tttaccagta gctttaatga tgcagtaaca agtgtaaaag ttttaggtaa gagtaaagac
    22801 gaaaatacaa aagcacctat aattgggaca tataaaaaag atgctgataa gtttggaact
    22861 ctacaaaaga ttaagcaaga tgaaaagata actaatgcaa aagaagctaa gaaagcagca
    22921 gaagcaatgt ttaattcggg tgaagaaaca ataagtgttg attgtgtagt agatataaac
    22981 agaataagag caggtgacaa agtaagttta aaaaataaag aatattatgt tatagatgtc
    23041 actcatacac tagattctag accaaaaatg aagctcaata tagggacttt agaatatata
    23101 aggaggaagt tttatacaaa tgactgatgc tagatttaat ggaattgcta gaatattgaa
    23161 agaaaatatg aataaaagtg tagcaaatgg cacttttgga atgggttgtg aacttgcaga
    23221 aataacagca aatggactta aggttagtgg ctataaagat gaaatacagg actatctagt
    23281 attagagaat ttaacattaa aagaagatta ttttactttt tcagatgaag ctttaagtgg
    23341 agaatataga cataagcata aaatagaaac tccaaaggaa ttgaagccac tacgtatagg
    23401 cgataatgtg ctagtagctg ttatgggagc tgaatttgta gtaattggga gggttgtaaa
    23461 tgccaaacct atttcctcaa agtgaaactt ttgaaactgt agaattaaaa aataatgatg
    23521 aaaatgaatt ggacctaaag ggttcttttt tatttgattt tgaaaaaggt gaatttgtta
    23581 aaaacgcaga tggaacacta aaaaaatgtg ataaggtgca ggcgtacaaa caatggtgtc
    23641 aaaaggctat attaacacct agatacaaaa aagcagctta tacaaacatt tatggaagtg
    23701 aaataaaaga cttaatagct agtaacttat ctcaaagtgc aaaagagctt gaaataacta
    23761 gattaataaa agaaactatt ttggttcatc cttacacaaa agaagtagga gagtttagct
    23821 ttaattggtt ggagaatagc aggttagtag agtatgaatt tgatgtacta acaatagatg
    23881 atgaaaatat agtaattgat ggcaatataa aaaggtaggt gattatatgg aaagagagct
    23941 acctatacca gtatttttaa cagaagatga ggactctgta catgaaagga tgttaagcaa
    24001 ctttcaagat gtttctacat tagaaggtga cttcatctat gatgcaacaa gacctacagc
    24061 agagcagata gctgaattaa aacaactagg attacaaaat aatttaaaga tagcatttcc
    24121 tcagacttct tatggaactt atttagagtg gcttggtgaa tgtaaaggag tatttaaaaa
    24181 tcaaccaact aaggctactg gagttattac atttacaggt gtacaaggaa ctatcattac
    24241 aaaaggaact atagtaacta ctattgcaac tgatgaaaaa cagagcatag aatttgagct
    24301 tcttgaaacc aaaactatag gagaaaatga aacagtagat attaaagcag aaagtaggat
    24361 tgtaggaact atagggaatg tgtctaaagg tagtatatcc gttttactag gttctattaa
    24421 tggtgttaaa tcagttacta ataaagattt caaaggtgga acagatatag aagatgaaga
    24481 acattttaga gaaagagtcc ttgtagcaga gcaagaagac aaacttagtg gagctagttc
    24541 agattatata agatgggcta aagaagtaga tggagttgga tatgcttatg tagttcccga
    24601 atggaatgga gcggggacag taaaagtatt aatactagat aaaaatagaa aagcagcaac
    24661 acaagagtta atagacaagg ttcaagaata tatatatcca ttaaatatat cagaaggaga
    24721 aaatagagat gggaaagctc ctatcggtgc attagttaca gttgtaacac ctgacacatt
    24781 acttattaat gtaaaagcta gttttatatt tagtaacagt tttaatgaag aaacagtatt
    24841 aaacaatcta aaaactaaga tagataaata tttagataag attgatttag ggggaacagt
    24901 ttcatacaat gctatacaag cgatagtagg ttctatgatg ttgacagatg aaggtataca
    24961 agacttttct aatcttacta taaatgatgc aaaagaaaat ataaaattgc aagaccaagt
    25021 ggtcggaata ggggaaatag ttaacgaggt ggttggatga taacttctaa aaaaggtaaa
    25081 gaaatgcttc taacattatc tcctatctat gaacaatctt tagttatgaa ctctatatat
    25141 gaagctatag gaagcgaatt tgataatcta gaattattaa ataaagaaat agagttacaa
    25201 ttatttcctc aaactgctac atggggactt gaattttggg aaaatagggt aggtttatct
    25261 actaatatag atgaagatat agaagctaga agaagaaaag tcattgctaa gcttcaaatg
    25321 aaatatattg ttaatcctaa cagactagca actataataa aaagctatac tggtacagat
    25381 gtatatataa aagaaaatat agctccatac acttttaaag taactgctaa tgttgatgat
    25441 gttattaatt atgaagattt caaatatata acaaataaaa cgaaaccctc tcatcttcat
    25501 tggatgcctt cttttgcact caaatttaca gatatagaaa aatttgaggt aaagatgatt
    25561 aatcgaatat ttatagattt tagagggaat ataagtaatt tcttagatgg catgtggtta
    25621 ttaaatggta gtaaaaactt aagtgcttat atactttata atgagccaat aagcttaaac
    25681 atgaaaaata agttatttgt aaaagaaagt gaagtattta caaatcttaa agtaatcatt
    25741 aaaaagaatt tatattattt aaatgggcta gaaatgttaa atggaaataa actgctcaat
    25801 gcagaattaa gagaggaagt gttataagta tggcaaatgc agtaacaaca gacattgcaa
    25861 gacaaaaaat gtgtaaagct cgagcgggtg atataacatt acctactata gttagcatgg
    25921 catttggaga tggaggaatt gggaatgatg gaactataat agctccactt tcaagtgata
    25981 tagcgttaaa aaatgaggtg tttagaaaag atatagaaaa ttatgtatat ccaatcccaa
    26041 ctacttgcag atattcaacc actctattaa aaaatgaagc agaaggaaaa aacataaatg
    26101 aaataggttt aatagattct gatggcgatt taattgcaat taaatctttt ggaaataagt
    26161 ataaagacag tgatatggaa atggtttttc agatagatga cgagttctag gaggtgaata
    26221 aatgcctaat gaattagatt ttaataatga gattgaagaa tatttaataa ctacaccagc
    26281 tcatgcaaat gagtttaata atcgacaaca aaaattgtta gacaatgata aatatttaaa
    26341 taataaaatt gatacaacta aaacagagtt aaatactaga attgacacag aaaatgagaa
    26401 acaaaatatt aaaattgacc aattaatcgc aggtggttca aatgtggcat ctactcaaat
    26461 aataacaatt gatgattggg ttgaggatgc agaaaatgga ttcaaagcaa ctgtaacaca
    26521 tagtttgtta acacagagaa tagttgtaaa tattatagat gctactacaa aagaaaatgt
    26581 agttacaaac tttaaaatta tagatgataa ttctattgag attagaagtg aaacaaggtc
    26641 agaattaaac gtttatgtga taaatggaaa tgcagaaact cattttatta atgcaactgt
    26701 agatgataac agagtgtctg aaatgactac ttattcatct aagaaaatag aggattctat
    26761 tagcagtata cagcttatag ataccagtat aagtattaca gatgctaatg atagatttac
    26821 aagtgataag ttagatggag tattagagga aataatggta gaaataagtg gtcaaagaac
    26881 taaaggaata actatagtga ataatttaat agatatgata taagcgaggt gaaaatatga
    26941 cagaaaaatt aactgaaaat gctagtttag gggaacttat ggcagcatta gaaaatgtac
    27001 aaactgattt tcaaactggt aaaaataata tatctagtgc attgggtagt ccttttattg
    27061 gaacagataa atttggtaca actaaaacaa aaatagaaac attaaaaaat gtattagtgg
    27121 agacgattaa ttctaaaaat gtttcagcaa catcatctga aacatttact aatttgattg
    27181 aaaaagttaa ctggattttt caatcaatag aaattttttc tttaaaaaat agaattcaag
    27241 ctacaacttt aaacactcct agcatcgttt acaatgaagt atctagtata aaaggcacat
    27301 taagattcac aggcgaactt aaagcgtcta aaatgcgtgc tgattatgca acagcaaaaa
    27361 tagagatact atgtggaaac cgaaaagaat acttttatgt tactgacgat actcctagtg
    27421 catcttcttc ttttgtaaga tttacaaaag atattattgt tgagaatggc atggatataa
    27481 aagtacaaat attattaaca tctgtaggag caggaaattt agatggttca tatgcagctc
    27541 gtgcagaaat agaaaaatta acaatattaa ggtaggaata aattatgaaa aaacaagtat
    27601 attataattc tttagatgaa aaagaaaaaa taattagtga aaactctaat ttatatgtta
    27661 tagaaatata tgaaacttta aatgaaaatt atttagtgtt atcaagtagt ccaatacaag
    27721 atgaaaaact tagttatgaa gaattagaaa atgaattatt aattatgact aatgaattac
    27781 aaggaggatt gttataatga atataaataa tgttgtggta agaatattag cagaaagaat
    27841 attaaatgga gggttaaacc ctttgaaaaa tagagagttt caacttgatg atgtaactaa
    27901 cacagaatac agaaaagcag tagaggatta tattataaaa aatagtggag tagtagaagg
    27961 aatagaacca acagcgtagt aggttct
//
LOCUS       DAGQVA010000050        27688 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.050, whole genome shotgun sequence.
ACCESSION   DAGQVA010000050 DAGQVA010000000
VERSION     DAGQVA010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27688
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.050"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..189)
                     /locus_tag="MIV85_002425"
     CDS             complement(<1..189)
                     /locus_tag="MIV85_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2961755.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILIS"
     gene            374..718
                     /locus_tag="MIV85_002426"
     CDS             374..718
                     /locus_tag="MIV85_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBY2961756.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTSIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            749..2350
                     /locus_tag="MIV85_002427"
     CDS             749..2350
                     /locus_tag="MIV85_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBY2961757.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            2369..3469
                     /gene="dprA"
                     /locus_tag="MIV85_002428"
     CDS             2369..3469
                     /gene="dprA"
                     /locus_tag="MIV85_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBY2961758.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            3502..5589
                     /gene="topA"
                     /locus_tag="MIV85_002429"
     CDS             3502..5589
                     /gene="topA"
                     /locus_tag="MIV85_002429"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBY2961759.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            5754..6539
                     /gene="codY"
                     /locus_tag="MIV85_002430"
     CDS             5754..6539
                     /gene="codY"
                     /locus_tag="MIV85_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBY2961760.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            6646..7911
                     /locus_tag="MIV85_002431"
     CDS             6646..7911
                     /locus_tag="MIV85_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBY2961761.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            7942..8712
                     /locus_tag="MIV85_002432"
     CDS             7942..8712
                     /locus_tag="MIV85_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2961762.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            8821..9267
                     /locus_tag="MIV85_002433"
     CDS             8821..9267
                     /locus_tag="MIV85_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBY2961763.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            9285..10478
                     /gene="nifS"
                     /locus_tag="MIV85_002434"
     CDS             9285..10478
                     /gene="nifS"
                     /locus_tag="MIV85_002434"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBY2961764.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            10532..10972
                     /gene="nifU"
                     /locus_tag="MIV85_002435"
     CDS             10532..10972
                     /gene="nifU"
                     /locus_tag="MIV85_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBY2961765.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            11261..12340
                     /gene="mnmA"
                     /locus_tag="MIV85_002436"
     CDS             11261..12340
                     /gene="mnmA"
                     /locus_tag="MIV85_002436"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBY2961766.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    12483..12721
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            12789..15428
                     /gene="alaS"
                     /locus_tag="MIV85_002437"
     CDS             12789..15428
                     /gene="alaS"
                     /locus_tag="MIV85_002437"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBY2961767.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            15453..15710
                     /locus_tag="MIV85_002438"
     CDS             15453..15710
                     /locus_tag="MIV85_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBY2961768.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            15720..17891
                     /locus_tag="MIV85_002439"
     CDS             15720..17891
                     /locus_tag="MIV85_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961769.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            18097..18522
                     /gene="ruvX"
                     /locus_tag="MIV85_002440"
     CDS             18097..18522
                     /gene="ruvX"
                     /locus_tag="MIV85_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBY2961770.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            18600..18887
                     /locus_tag="MIV85_002441"
     CDS             18600..18887
                     /locus_tag="MIV85_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBY2961771.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            19169..19627
                     /locus_tag="MIV85_002442"
     CDS             19169..19627
                     /locus_tag="MIV85_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBY2961772.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(19744..20481)
                     /locus_tag="MIV85_002443"
     CDS             complement(19744..20481)
                     /locus_tag="MIV85_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBY2961773.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFIAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            20698..22374
                     /locus_tag="MIV85_002444"
     CDS             20698..22374
                     /locus_tag="MIV85_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBY2961774.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            22580..22780
                     /locus_tag="MIV85_002445"
     CDS             22580..22780
                     /locus_tag="MIV85_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBY2961775.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            22834..23997
                     /locus_tag="MIV85_002446"
     CDS             22834..23997
                     /locus_tag="MIV85_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBY2961776.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEIISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(24208..24630)
                     /locus_tag="MIV85_002447"
     CDS             complement(24208..24630)
                     /locus_tag="MIV85_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBY2961777.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(24651..25487)
                     /locus_tag="MIV85_002448"
     CDS             complement(24651..25487)
                     /locus_tag="MIV85_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2961778.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFGSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            25785..26381
                     /locus_tag="MIV85_002449"
     CDS             25785..26381
                     /locus_tag="MIV85_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBY2961779.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            26411..27130
                     /locus_tag="MIV85_002450"
     CDS             26411..27130
                     /locus_tag="MIV85_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBY2961780.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            27132..27671
                     /gene="scpB"
                     /locus_tag="MIV85_002451"
     CDS             27132..27671
                     /gene="scpB"
                     /locus_tag="MIV85_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBY2961781.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
BASE COUNT        11231 a         2907 c         4981 g         8569 t
ORIGIN      
        1 agaaataagt ataaatttat tctcatttga taaagaaaaa aatctaactt gattatttat
       61 tataattaga aataatatta tcatagttat gaccggatac aatgtatttt caacattttt
      121 caaatagctt acaactaata taaataaaga taaatatcgt ataaaagcaa ctaatttttc
      181 tctgttcatt aaaggcactc ctccaaaaaa aataaacttt tcctatgaaa actagaataa
      241 tatcataaaa gaataaagtc aatagaagta tttattaata ttgatggaaa taaaatcaat
      301 ccaaaaactt gaatagtaaa attgtatact gaccataatt taaaagtgaa aatttaatgt
      361 attggagtga ataatgaata ataaagaaaa aggtgatttt ggagaaaaag tagcagttaa
      421 ttatttgcta tcaaaaggag caaagatact agaaaaaaat tacagattaa agatagggga
      481 aatagatata atagcaaaaa tggaagatga aattatattt gtggaggtga aatcaaggtc
      541 taacataaag tttggctacc cttgtgaatc tgtaagcttc aaaaaaagaa aaaagataat
      601 tggagttgca agttattata ttataaaaaa taacttaaat aacacttcca taagatttga
      661 tgttatagag gtatatttat tagaaaaaag aataaatcac ataatgaatg ctttttaaaa
      721 aagataatgt ttttggaaag gattaaatat gttaagtatt attaattcaa gcaacttagt
      781 aggaatcgac agctttttag ttaaggttga agtagatgta agcaatggaa tacctagttt
      841 taatattgtt ggtcttccag gcaaagaaat taaagaagca agagaaagag taaagtcagc
      901 aattcttaat agtggatata aatttccaag cacgagaata gttgtaaatt tatcaccagc
      961 agatataaaa aaagaaggag cttttttaga tttatctata agtataggcc ttttaagaga
     1021 gttaataaaa aaagatgaaa attacataag agaaagtatg tttataggag aattatcatt
     1081 agatggaaaa ataagaaaag taagaggtat attgcccata attatgggtg caaaaactca
     1141 gaacataaaa cgtattttta taccaattga gaacataaaa gaaagtctat ttgtagatga
     1201 aattgatata attcctatta aaagtttaaa agaatgtgtc gattttttaa acgaagagat
     1261 aaaagtcgat aaagtaagga taatgtcttt tttggatgat aagtcaagaa aagagaacga
     1321 agaattagaa aaagataata gttatataga ttgcaaatat actaagatta ataatgaaga
     1381 aagtaaatat gatgaagact ttaaagatgt aaaaggaaat tattttgtaa agaggagtgc
     1441 agaaattgct gctgctggaa atcataatat gtttatgatt ggacctccag gctcaggaaa
     1501 aactatgatt gcaaaaagag taaggacaat tttaccagat ataagtgtag aagaaatgat
     1561 agaagtaagt aaggtttata gtatattggg tatgataaat gaaactaaag gaataattga
     1621 taaaagacct tttagagcac ctcatcatac aactacaaag caatctttaa ttggaggagg
     1681 aatggatgca agacctggag aaattgcttt agcacataga ggtatcttat ttttagatga
     1741 gatagccgaa tttgatagaa aaatacttga gactttaaga caacctatag aagatggata
     1801 tgtaaatata tccagagtaa agtacagtgc aaaatatcct tgtagagtac tgttagttgc
     1861 agctatgaat ccatgtccat gtggttatta tatgtcagag acagagtgta gatgtagaag
     1921 taacgaaatt gatagataca taaataaaat atcaggtcca ttgttagata ggtttgatat
     1981 ttttgtagaa gttaattcta taaaatattc agattttaat tctttaaaac aagaagaaag
     2041 ctctcaaaaa ataaagagaa gagtagaaaa tgctagaaaa atacagataa atagatttaa
     2101 gaaggataat ataaaaaata atagtgaaat taaagcttac aatttattta aatattgtaa
     2161 actggaaaaa gaagcttcaa aaacggctga gatgatattt aataaataca acctaagcag
     2221 tagaagttat acaaaacttt taaaaatggc aagaacaata gcagatttag aagaaagaga
     2281 cttgataaat tcacagtgta ttatagaagc tttttcattt agaaaggctt attatagtta
     2341 ttttaaatag ttttttgagg tggattttat ggaaaaaaga gatacttatt tatggttaaa
     2401 atcaattggt ggaataacaa caaaaacaat tgaaataata gaaaatgaaa tagtaaatat
     2461 tgaagatata tttgattttt ctgaaaaaga aatatataat ttaaaaaata taagcttgaa
     2521 tattagaaaa aatatagtaa aatatagagg tcacgcttat ttagaaaata taaaagaact
     2581 actttacaaa aaagcgatta aatatatttg taaatatgat aaagaatatc ctgaaaattt
     2641 aaagaatata tacaacgctc caaagttatt attctacaaa ggtgacatag gcttagttaa
     2701 taataatttt aatatagcta tagtaggttc aagaaaacct acagcctatg gaattaattg
     2761 tgcaaaaaca ataagttgtc aactatccca atatggagtt aatatagtaa gtggattagc
     2821 tataggaata gatgcatact cgcacatagg ttgtatgagt ggaaaatcta aaactatagc
     2881 agtacttggt tcaggagtag acaatcctct tccaaaacaa aatttacatt tatcaaataa
     2941 aatattagaa aatgggggat tattattatc agagtataat attaactcga cagtagcccc
     3001 gtaccatttt tctaatagaa atagaattat cagtggttta agtgatggag tagttgttgt
     3061 agaagcagca ataaaaagtg gtgcactaat cacagtagat tttgctcttg aacatggaaa
     3121 aaatgttttt gcaatacctg gtaatataaa ttctcaaatg agtagaggtt gtcataaaat
     3181 tataaaagaa ggtgcaaaat taattgaaaa tatagatgat attttaaatg aatataacat
     3241 atttaatatt attgataaaa aaataaatca aaaatatgat aatataagtc taaatgccaa
     3301 gtctaagcaa ataattgaag ctataaaaag agaaggaaac ttgcatatag atagtatttg
     3361 tgattatact ggtatagaaa taaagtatgt aaattcaata atcaatgaat tagtactaaa
     3421 tgagttagta gtagaaatga ataataaaac gtacagttta aatgtataaa ttaagattag
     3481 gtagtggggg tgtatggttt tatggccaaa acattagtca tcgtagaatc gcctgcaaaa
     3541 gctaaaacta tagaaaaatt tttagggaaa agtcattaca cagttaaagc atcagttggt
     3601 catgtcagag atttacctaa aagtaaatta ggtgtagata tagaaaataa ttttgaacct
     3661 caatatataa atataagagg aaaaggcgat gtaataaaag aattaaaaaa agaagctaaa
     3721 aaatctaaac aagtatatct agcaactgac cctgatagag aaggtgaagc tatatcatgg
     3781 catttagctc atatactaaa tttagatgaa tctgaggatt gtagaataga gtttaatgag
     3841 ataactaagg atgcaattaa aaaagcaatt aaacatccta gaaatattga tataaatttg
     3901 gttgatgcac aacaggcaag aagagtgcta gacagacttt taggttatca aataagtcct
     3961 atattatggc aaaaggttag aaaaggtctt agtgcaggta gagtgcaatc tgttacaaca
     4021 aagttaattt gtgacagaga aaaagaaata aaggcattta ttccaaaaga atattggaca
     4081 atagatgttg aggctaagac agtaaaagac aaagatataa ctttgaaatt ttatggtaaa
     4141 aatgatgaaa aaattgaatt agaaaatgaa gaagctgtaa atgaaatact aaaagaaatg
     4201 gaaggtaaag atttaaaggt tgagaagata gaatctaaat caagacgtaa atcagctcca
     4261 aaaccattta caacaagtat gcttcaacaa gaaggagcaa ataagttatt ttttactact
     4321 aaaaaaacaa tgatgatagc acaagaatta tatgaaggta tcgacataga aggtgaaggt
     4381 actgttggtc ttatatcata tataagaact gactctaaaa gaatatctga tgaagcaaaa
     4441 gaaaaagcta agggctatat cgtaaacaat ttaggagaaa actactataa aaacactggt
     4501 gataaaaaag aaaaaaagga tactaaaaag gttcaagatg cccatgaggc aataagacca
     4561 acctcagttg atagaactcc tgagagtata aaagcctcat tgagcaaaga ccagtacaag
     4621 ttatacaatt taatttggag aaggtttgta gctagtcaaa tggaagattc agtgtttgat
     4681 atactaaatg tagaatgtaa aataggcgat attgtattta aggcaactgg ttcaaaaatg
     4741 aaatttgatg gttataccaa ggtatataat ttttcagaaa gagaagacaa aattttacca
     4801 agtatagaaa aaggagatat attaaatata gaaaatatat tgccagacca acattttaca
     4861 caaccaccag caagatatac agaagctagt ttagtaaaaa cactagaaga actaggtata
     4921 ggtagaccaa gtacgtatgc tccaacaata gctactatac tgaatagaga gtatgttgaa
     4981 aagcaaggca caagtctatg tccaacagaa cttggaataa tagttactga tattttggaa
     5041 aataatttcc ataaatttat agatgtagat tttactgctg atatggaaag taaacttgat
     5101 gttatagaag aaggcaatac agattggaaa aagattgtat cagaatcata tgcaccactt
     5161 aaagaggcta ttgaagaagc tcttgaaaat atagaaaaag taaatatgga tgaagaaact
     5221 gatgagattt gcgagaactg tggttctaat atggttatca aatatggtag atttggaaag
     5281 tttatggctt gtaaaaacta tcccgattgt aaaacaacta gaccaattat gaataaaatt
     5341 ggtgttaaat gtccaaaatg tgaagaagga gatattatac ttagaaaatc taaaagaggt
     5401 aaagcttttt atgggtgttc taattatcca aactgtgact ttgtagcttg gaataagcca
     5461 acaggagagt tttgtgagaa gtgtggttca tatatggttg aaaaagtgac taaatctgaa
     5521 acaaaaacag tgtgttctaa taaagaatgt aataaagaga caaaagagca taatgacgga
     5581 aaagagtgaa aattgaaaaa aatcacataa ttctcttgaa aaaggttcca atctatgata
     5641 atctttcaag tgtaaacaac taatagaaaa ataaattttc attaaatgtg aaaataatat
     5701 tagaaaatat aaaaggttat taaaaggcct aaatttcatg aggagatgat taaatggcaa
     5761 gtgaagtgtt acaaaaaaca aggaaaataa ataaaacatt acaaacaagt ggtggaagca
     5821 gtgtctcttt tgatttactg gccggagcat tgggcgacgt tttaagttct aatgtttatg
     5881 tagtaagtgc aaaaggtaaa gtactaggtc ttcatttaaa tgatgttcaa gacagttcag
     5941 ttatagaaga tgagtatact aagcaaaaga aattttcaga tgaatatact caaaatgtgt
     6001 taaaaattga tgaaacatta gaaaatttaa atggtgagaa gatattagaa atctttcctg
     6061 aagaacatgg aagattacaa aaatatacta cagtagttcc aatattagga agcggtcaaa
     6121 gattaggaac attggtactt tcaagatatt caaattcatt caatgatgat gatttagtaa
     6181 tagctgaata cagtgcaact gttgttggtc ttgaaatatt aagagcaata ggtgaagaat
     6241 tagaagaaga aatgagaaag aaagctgtag ttcaaatggc aataggcact ctgtcctact
     6301 ccgagcttga agcagttgaa catatttttg ctgaattgga tggaaaagaa ggtctacttg
     6361 tagcaagtaa gatagctgat agagttggta taactaggtc tgtaatagta aatgcactta
     6421 gaaaatttga gagtgcaggt gtgatagaat caagatcatt aggtatgaaa ggtactcata
     6481 taagaatact taatgacaaa cttacagatg aattaaaaaa attaaaaaac aatcaataat
     6541 ctatatttta taggtttaga ttagaaaagg tatctatttc aaatagatac cttttttaga
     6601 cgaattatta aggtaatgat aagtatatta aaaaggagtg agaaaatgcc tttagcagat
     6661 aaaataagac caaaaacaat gaatgatgta ataggtcaaa gtcatataat aggtaatgga
     6721 aaaatattgt ctaagatatt acaatctaat tttttaccaa atatgatatt ttttggtcct
     6781 cctggtgttg gtaaaactac agtagcggaa ataatagcag aaagaagcaa taaaagcttc
     6841 tataaaataa atgctactaa ttcatcttta gaagatataa aaaaggtgat atcagagctt
     6901 ggaagtataa ataatgtaaa tggagtccta ttatatatag atgaaataca aagttttaat
     6961 aaaaaacagc aacaatcaat attagaattt atggaaaatg ggagtataac tttgattgct
     7021 agcactacag aaaatccata tcattatgta tataaagctc ttttaagtag gtctactgta
     7081 tttgaattta aacctttaga aaaacttgat atagaaaaag gactgaaaag agctgttgaa
     7141 gtattaaatg aagatagcta catggatatt gagtgcaata ataatgctat tgaagatata
     7201 gcaattcttt ctgatggaga tatgagaaga gccttaaata ttttggaagt ggtagtctat
     7261 tcaactaaac caaataagga taatataact tatatagatt cagatgtaat aagggcatct
     7321 acatttaata aaattataaa ctatgacaaa aatggtgata gtcattatga tattttaagt
     7381 gcatttcaaa aatctataag aggaagtgac ccacaggcat ctatacacta tctagcaaga
     7441 cttataaaag gtggagattt gataagtata tgtaggagac ttttagtaat agctagtgaa
     7501 gatataggtt tagcttatcc aaatgctatt gtaattgtaa aggcatgtgt agactcagct
     7561 atgcaacttg gatttccaga agcgaaaata ccattagcag aagctactat tcttttggct
     7621 acatctccaa agtctaattc tgcatgtata gcaataatga aagctatgga tgaactggat
     7681 aaagagtttg ttaaggatat accaaatagt ataaaggatg ctcactattc tggttctaaa
     7741 gaaataggta ggggttgtgg atacaaatat cctcataatt ttaaaaatca ttatgtaaag
     7801 caacagtatt taccagatag cataaaagat agtatttatt acataccaca agaaaataaa
     7861 actgagaaaa atataaaaaa atatttagaa tatctaaata gtgattttta gactgaactt
     7921 tatgtatcgg gggtagatat tatgattata aaacttaact caacttatca cagtagagtt
     7981 atgaaatact taaaaaaaga acctgagtac aatttgttta taatagggga tattgaaaga
     8041 tatggatatg gaaataattt tttaaatata tgggcagatg tgggtgaaca tggtgaaata
     8101 aaggcaatat tacttaaata ttttgaattt atgatgtttt attctgatgg agagtatgat
     8161 gttgaaggtt tttataatct acttcgtaat actaattacg aagaaatatc tgggaaaata
     8221 tgtgctgtag atgctttagc aaagagatta ggacttaata atttaaaggt agttgatttt
     8281 tgcaaacttc aaactaaaaa gtttttgata gataataatt gtaatgcaaa ggttaagaga
     8341 attaggcttg gaaatctaaa aaagacagta aaactttatg acttaataga tgaatttcac
     8401 agtacaactt tagagaattt aaaaaatgga ctaaggacag gtagaggata ttgtatagag
     8461 attaacaaac aggtggtgtc aatggcaaag agtacttcag aaaataggac tcatgcaatg
     8521 ataattggag taggaacaca tcctaaatat agagctaaag gacttgctac aaaatgccta
     8581 attaaactat gttcagagtt actgagagaa aacaaaattc cttgtttgtt ttatgataat
     8641 gaagaggctg gaaagatata taaaaaacta ggatttgaaa acattggaaa atggggaatt
     8701 tattcaaaat aaaaaattaa aattaatctt gacaaaatta gtagggtata ataaaattat
     8761 cttgaaagta attcctacta aaacagtatg aattagattt ctatatagag gtgataatat
     8821 atgaagttgt ctactaaagg tagatatgga ctaaaagcaa tgtttgaatt agcattaaat
     8881 caagacaatg gaccagtatc attaaaattt attgctaaga agcaaaaaat atcagatcag
     8941 tacttagaac aaatattttc atctttaaaa aaatcgggtc tagtaaaaag tgtgagaggt
     9001 gctcaaggag gttatttgct ttcaaagaat gctgaagaca taacagtagg agatatactt
     9061 gtagtattag aaggaccagt tgcattatct gactgtgtac tagatgaaga tgtatgtgaa
     9121 aactcaaaca tgtgtgtaac aaaaatagtt tgggaaaaga tgaaaaaggg tatagaagat
     9181 gttatagatt caattactct taaagatatg ataaatgact ataacaaaaa taaattagaa
     9241 aatgatataa caaatattaa aaaatagatt tggagatgaa tgtaatggaa aaaagaagat
     9301 tgtatatgga ttattctgca acaacaccta ttaaaaaaga agtattggat gcaatgatgc
     9361 catacctaac agattatttt ggtaatgcat ctagttttca cacattcgga agagaagcaa
     9421 aagatgcttt ggataaagca agagaacaag tagcagccct tataaatgct gaacctagtg
     9481 aaatatattt tacagcaggt ggttcagaaa gtgataactg gacactagag ggtgtagctt
     9541 atgctaataa aaacaaaggt aatcatataa taacttcaaa aatagagcac catgcaatac
     9601 ttcatacatg tgaatactta gcaaaacatc atggatttga aataacttat ttagatgttg
     9661 atagcgaagg aaaagtagac ttaaagcaac tagaagattc aataaaagat actactatac
     9721 ttataagtat aatgtttgca aataatgaaa taggaactat acagcctatt aaagaaatat
     9781 ccgaaatagc taaaaaacat aagatattat tccacactga tgcagtacaa gctacaggta
     9841 atattccagt agatgttaaa gaattaggaa tagatttgat gagtatgtct tcacataaaa
     9901 tatatggacc aaaaggtgta ggagctttat acataagaaa aggtgtaaga cttcataact
     9961 ttgtccatgg tggagcacaa gaaaaaagca aaagagctgg tacagaaaat atacctgcaa
    10021 tagttggata tggaaaagca gcagaattag ctaaggaaaa tatgcaaaat catgtagaaa
    10081 ctttaactcg tcttagaaat aagttaatag atggtgtgtt agaaagaata ccttacacaa
    10141 gagtaaatgg tagcttagaa aatagattgc caggaaatgc aaactttgca ttccaattta
    10201 tagaaggtga aggaatactt ttattattag atatgttagg aattgctggt tcaagtggtt
    10261 ctgcatgtac ttctggttca ttagaccctt cacatgtact tcttgcaata ggtttaccac
    10321 atgaaatagc acatggttca ttaagactta cagttggaga ttttacaaca gatgatgata
    10381 tagattatat actagagaac ttaccaaaag taatagaaag acttagaagc atgtcaccac
    10441 tttatgatga tgcgaagaaa caaggtttag taaaatagac ataaagataa agcataaaaa
    10501 atagacataa attgagtagg aggaaaagat aatgcaatat agtgataaag ttatggaaca
    10561 ttttatgaat ccaagaaata tgggagaaat tgataatgca agtggtgtag gtgaagttgg
    10621 aaaccctaca tgtggagata taatgaagat atttttagac atagatggag atgtaataaa
    10681 ggatgttaag tttaaaacat ttggctgtgg ttcagctata gcaagttctt ctatggcaac
    10741 tgaaatgata aaaggaaaaa ctataaaaga tgcattagaa cttacaaata aagctgttgc
    10801 agaagctttg gatggtttac caccagtaaa gatgcattgt tcagttttag ctgaacaagc
    10861 tgtaaaagca gctcttatag attatgctca aaagaacaat atccatatac cagaattgga
    10921 tggatatgtt atagatgatg ctcatgacca tgatgttgaa gaagaagaat aaaaataagt
    10981 gattgtgtta tgagaagttt acaatgatta aaaagaagta ctaatgatat aattaggaca
    11041 taaaaaatag ctgtttttaa aatggctatt ttttattgcc taaattaagt attttaactt
    11101 gatttagagg ttaattagtt aacaaaataa tccataagat tcaaataata aagatgatta
    11161 tttttttaga aaatagaaca agctatattt taaataagta caatacttgc tctatatggt
    11221 ataataataa gtaatgcaaa agatgaggtg aaatttgttt atgaataaaa aagtaatgat
    11281 aggtatgagt ggaggagttg atagctctgt agctgcatat cttttaaaac aacaaggata
    11341 tgatgtcatt ggtgttacta tgaagttgtg gcaagatgat gatgttgttg aaattgaagg
    11401 tggttgttgt tctttatctg ctgttgaaga tgctagaagg gtagcaaata aaataggtat
    11461 accattttat gttttaaatt ttagagaagt gtttaaagaa aaagtaatag attattttat
    11521 agatgaatat ttggaaggaa aaactcctaa tccctgtata gcttgtaata aacatataaa
    11581 atttgatgat ttttataaga aggctagaca aataggttgt gattatgtag ctacaggtca
    11641 ctatgcaaag atagaaaagg atgaaagtac aggaagatat ttgctaaaaa aatctgttac
    11701 agataaaaaa gaccaaactt atgcacttta taatcttaca caagagcaac tagagcatac
    11761 tttactacca ataggtgact atgaaaaaga tagagtaaga gaaattgcta aggaaatggg
    11821 tatggcagta cacaataagc ctgatagtca agaaatttgt tttgttaaag ataatgacta
    11881 tgcaaattat gtaaaaaaac attctaaaaa gcgtattgaa gaaggttttt ttgtagatac
    11941 taaaggcaat atacttggaa aacataaggg tatattatat tatactatag gccaaagaaa
    12001 agggcttgga attacttttg gaaaaccaat gtttgtaata gacataaatc caataaataa
    12061 taccatagtt cttggagaca atgaagattt atttaaaaag gaacttattg ctaaagatgt
    12121 taactttata tcaatagata cgttagaaga acccttaaga gttcaagcca aaataagata
    12181 ttcagcaaaa ccatcaccag ctactattca tagagtagga gaagatacta ttaaaatagt
    12241 ttttgatgaa gctcaaagag ctattactaa aggtcaatct gtagtaatgt atgatggaga
    12301 tattgtagta ggtggaggta taatcgagaa aagtttataa aaacatctaa aaaattaaaa
    12361 aaataaacaa taaagtatat taagagtaaa taaagtttat aaaataaatt tattgtatat
    12421 gaaaatatag tattgattaa ttttgtaaaa tttagtaata taattagtat attaattaaa
    12481 aaacaaatac agtgataagg aatagtaaaa tatttgatgt cttacagaga gagggaaatg
    12541 ctggaagccc ttagaatatg atatttgaag cagcctttta gtagcaatct tgaacaattt
    12601 atcttttata aagaagattt aagtagagat tgacggtagt tacgttatag ctaaggtttt
    12661 ccgaagatat catactttgt atgataatta gggtggtacc gcgattgtcc tcgcccctat
    12721 aaatttattt atagggacga ggttttttat ttaaacgaaa aaataaaatt tattaggagg
    12781 aacatgatat ggaaaagatg ggattaaatg aaataagaag taagttttta gaattttttg
    12841 agtcaaaagg tcattatgta gcaaatagtt attctttagt accaaacaat gataagagtt
    12901 tgttacttat aaactcaggt atggcacctt tgaaaaacta cttttcaggt gtagaagtac
    12961 ctccaagtgt gagaatgtgt acatctcaaa aatgtataag aacaggagat atagaaaatg
    13021 taggtataac tgcaagacat gctacattct ttgaaatgat gggtaacttc tcatttggag
    13081 attactttaa aagagagtca atcaaatggg gatgggaatt tgttacagaa tggctaaata
    13141 taccagaaga taagatatgg gtgactgtat atgaagaaga tgatgattct tatgatatat
    13201 gggcaaaaga aatgaatttc ccagaagaaa gaatggttag acttggaaaa gatgataatt
    13261 tctgggaaat aggtacaggt ccttgtggtc cttgttcaga aatatatttt gatagaggag
    13321 aagaatatgg atgtgacaat ccagactgta aaccaggctg tgattgtgat aggtatttag
    13381 aattttggaa ccatgtattt actcaatttg atagagatga agaaggaaat tatagtctat
    13441 tagaaaacaa gaatatagat acaggtatgg gtcttgaaag aatgggatgt attatgcaag
    13501 gcgtagacac tatctttgaa gttgatacaa ttaaatctat actagaagca gttgagaagt
    13561 taacaggagt aaaatatgga gagaatccaa aaaatgatat atcaataaga ataataactg
    13621 accacataag agctgtaaca ttcttagtta gtgatggagt gcttccatca aatgaaggaa
    13681 gaggatatgt tcttagaaga ctccttagac gtgctgctcg tcatggtaag ttattaggag
    13741 taaaagaatt atttttacag aaactaatag atgaagttat aaaagtaaat gataaagcat
    13801 atccagtttt agttgaaaaa gaaagttata ttaaaaaagt agttggaata gaagaagaaa
    13861 aattcaatga aactatagac caaggaacag aaatattgaa ctcttatata gaagtattaa
    13921 aaaatgaagg aaagactgtc ctaagtggtc aagaagcttt taaactatat gatacttatg
    13981 gcttccctat agacttaact aaagaaatat tagaagaaga acatctatct gtagatgaag
    14041 aagcttttaa tgaagaaatg gaaaagcaaa aagaaagagc tagaaatgct agaggaaata
    14101 tggatggaga aagttggaag gaagaccctc tatcaaaatt agaatctaca gttgacagta
    14161 catttaatgg gtatagtgaa atttatggtg aaggaactat tgaagctata gttaaagatg
    14221 atgagctagt tcaaagtgca gaagaaggcg ataaggtatc tatagtacta gataacacta
    14281 ctttctatcc tgaaggtgga ggacaagttg gagattgtgg attgataact aatgaaaact
    14341 tagttttaga agtattaaat actaaaaaag gtgctaataa tagtataaaa catataggta
    14401 taataaaatc aggaagaata agtaatgggg acaaagtaaa gacactcgta gatagagaaa
    14461 ctagaatgtc agctgcaaga aatcacagtg ctacacattt acttcataag gcattaagag
    14521 aagtattagg agaacatgtt aatcaagctg gttctttagt aactccagaa agacttagat
    14581 ttgatattac tcactttgaa gcaatatcaa atgaagaatt aaaagtaata gaagaaaaag
    14641 taaataatgt tattttatca tctttagaca taaaatgtga tattatgaat ataaaggaag
    14701 ctaaagaaaa aggagctaca gcactatttg gtgaaaaata tggtgatgag gtaagagtag
    14761 tttctatggg agattattct acagaacttt gtggaggaac tcacttgaca aatacttctc
    14821 aagtaggaat gttcaaaata ttatctgaag gtggagtagc agcaggtgta agaagaatag
    14881 aagcaataac aggaaaagct gtttatgaat acctaaaaga aagagatgga attatctctg
    14941 aagtttgtgt aaacttaaaa tctaaagaag ataatttaat tcaaagaata agttctttat
    15001 tagaagaaaa taaaaactta tctaaagaat tgcatgatat gaaagctaag atgagtttac
    15061 aatcagttga ttctattttt gattctaaag ttgaagtaaa tggagttaat ttgataacta
    15121 ataaatttga aggtatggat atggatacac taagagaaac agcagataat ctaagagata
    15181 agcttggttc tggtgtagta gtacttgcaa atgtagtaga tgataaagtt aactttgtag
    15241 ttactgccac taaagatgta ttagataagg gaatacattc aggtaatatt gttagagaag
    15301 ttgcaaaaat agctggagga aaaggtggag gaagacctaa tatggcacaa gcaggagcta
    15361 gtgatgtatc taaggttgac caagctttaa gctatgcaag tgaggttatt aagacacaag
    15421 ttaaataaca ttcactcaag gaggttttta gtttggaaaa agatttagac tacactatga
    15481 aatttgaagg aataccagaa gataggatga gtgtaggaga tactattgat tttgtatata
    15541 aagcattagt tgaaaaagga tataacccta taaatcaaat tatagggtat ctcctttctg
    15601 gtgattctag ctatataact agtcataaaa atgcaagagc tataattaaa aaatttgaaa
    15661 gagatgagat acttgaagaa gtaatcacgc actatctgaa tagaaagtag gtcaaataaa
    15721 tgagaaaaaa gattatgtcg ttgtttgcaa tagtcattat gatttttgta tcaactgcta
    15781 gctatggttt tgctgaagaa aaaggcaagg tcatatttat tgatatgaat aggaccaatc
    15841 ttggaagtat gatgaatatt ccaatcttga aaaatgagat agaaaagaga ggctatgtag
    15901 ctctcatgaa tataagaggg gatcaaggta ctgatgatag aaggtcttat gcaagtatgg
    15961 gtgcaggaac aagagctagt gtaactactg aagactatat caattttcaa aaagtagacc
    16021 aagatactgc taaagctttt gaagtcgcaa caggtcaaaa agctaaagaa ataaatgatt
    16081 taggcattaa tagatctata aatgaaaatc ttgagtatgg agaatatgga gcaaatttag
    16141 ggtcattagg aaaaacttta tcagaaaatg gtttaaagac atctgtaatt ggaaatgctg
    16201 atataattga aaataatcaa ttagttaaaa acagaaactt atgtttagta gctatggacc
    16261 aatatggaag gattgattca ggtaatattg ataatattaa taagaaagat tctaaaatgc
    16321 catttggaat atctacagat tatgataaat tactagatga aactaaaaaa tcctataaaa
    16381 atagtgatgc tatatttgta gaacttggag atacatatag attagatatg tatagattaa
    16441 atctaaatga taatacttat gatacaatga agaaaaatat tgtaaaaaat ataaataaat
    16501 atcttgaaca agtattttct atggttggag aaaatgacac tgtttatata gcaagtgcat
    16561 ttccaagtga cctagattat aagaataaga gaagactttc tccaataata aaatttagtg
    16621 gagaagggaa aggtctactg gaatctgcca caacaagaaa ggctggaatt gttgccaatt
    16681 tagatgttgg agtagatata ctaggtacat ttggtcttga aaataaagag atggtaggta
    16741 gaagttatac tttagtaaat aaagaggaca atattagcta tctaaaatca ctttatgaaa
    16801 ggatagtgtc tatatcttca ataaggtcaa ctattataaa tggctttgta ggcgtaatat
    16861 ctgcttcttg ggtaattgcc atgtttgcga ttttctttag aaattatatg ccacataaag
    16921 agcgtgtatt caaagtactt aaggagttta taaaattagg cataataatg ccactatcat
    16981 ttatgttagc tcctttgatg aattttaaaa ctccaatttc aatatctttg ggaatatttg
    17041 cgactacgct aatattatac ttgttaggta gaaaattatt taaggacaat gatataaagc
    17101 acatgggatt ttttgcaaca cttactattt tagtcatagt tatagattct gtatttggaa
    17161 catacttaat gcaaaataac ataatgagtt atgatgctgt cataggagct aggtactatg
    17221 gtgtaggaaa tgaatatgaa ggtgtaacta tagcaagtgc agtatttggc ttagcagtat
    17281 tattacatta taagaaggta tctaaattac ttgttgtaat tttttcatta ataatactta
    17341 taactagtgc atatccttca atgggtgcaa atgttggtgg agctatatca gaatgtgtag
    17401 catatttgtt gtttataatg cttatatatg acattaaaat agattttaag aaagctgtat
    17461 tattagctgt ttcagctgta gttgtcgttt ttgcatttgc agctttagat atactttcag
    17521 gtagtgaatc tcatttaggt atgtttgtac agagaatttt cctaaatgga ccaggagaaa
    17581 tattacaaac atttggaaga aaaattcaaa tgaatatgca actagcacag acaagtgtat
    17641 gggtaaatat tttacttgta ggaattggag taattgcagt gcttatattt aaaccatcta
    17701 gacactttag aaagataatg aataattttc caatcttgtt taaagggttt attgcatcta
    17761 tggttggttg cataattaca cttttagtta atgattctgg aatagttgct gcatctacag
    17821 catctatata tatacttata ccactaataa taataagtat aaatatgata atatttgaaa
    17881 aaaataacta aaaaaatttt tactgttcat ataggattta aataaaaaat gcaatatgat
    17941 tattaatgta aactggatgc ttacataaaa aatcatattg caatttttat gattgattat
    18001 gtaaaattat atgaagcagt aagcctgtga ccttagttat gagaggttca gaatatgtat
    18061 ttaatctata gaatataaat agataaagga ggaactatgt tagatggaag aataatgggt
    18121 cttgatgttg gtgataaaac tattggagtt gctgtgagtg atttgatggg attaactgca
    18181 caaggtgtaa aaacaataaa aagagttggc aagaaaaaag atattgaaga gctaaaagca
    18241 ataataaaag aaaaacaagt aaataaaatt gtatcaggat taccaaaaaa tatgaatgga
    18301 actttaggtc cacaaggaga aaaagtaatc aagttttgtg aattggtaaa agcagaaaca
    18361 ggtattgatg tagagttttg ggatgagagg ctttctacag tagcggcaga gaggtcttta
    18421 ttagaagcag atgttagtag acaaaaaaga aaaaaggtta tagatatgtt ggcagcagta
    18481 ataattttgc aaggatattt agattttaaa ataaattcat aaaagaacta taaaattgaa
    18541 tacttatgat atataatata aataataaaa ataaaaataa atttgaggtg aatgacatta
    18601 tggaagaaaa tataataaat ttaatagacg aaaatggcgt tgaaagccaa tttgaaataa
    18661 tattaacatt agaagcagaa ggaaaagagt atgcaatatt aatgccttta gatgatgaag
    18721 aagctgaaga agctttaatc tttagaattg atgaggatga agaaggtgaa atcttaatac
    18781 ctttggaaag tgatgaagag tatgaaactg ttgtagctgt gtatactgct ataatggaag
    18841 aagaaggttt aaattacgac gaagatgaat caaatggact taactagata agtaattaag
    18901 tttgtatata aaaatcagat atttattata tttgctttaa ttaaacctta ttaattgtaa
    18961 aagcatttat agtatatatc tgtttttttg ttttttatta aaaataccaa aaaatttatg
    19021 aattttggtg aataatatat cttttatggg tatatattta tattatgaga ataaattaaa
    19081 tttatttaaa tgtcttgaca aaaaatgaat tatcaattac aatattattt aataaagatt
    19141 atcaattgaa aatagtaagg gtgatgttat ggcaaataca atggatttat taaaagacaa
    19201 gttaaaagaa actggtttta agattacgcc acaaagaaga gcaatagttg aaatattgct
    19261 taaacatgac cattcacatc taagtagtga ggaaatctat gatttagtta gggttgactg
    19321 tcctgaaata ggcttagcta ctgtatatag aacaatgcag ctattggatg aaataggatt
    19381 aatatcaaaa ctaaacttag acgatggatg tataagatat gagattagtc tacataaaga
    19441 agactgtcat aatcatcatc atcttatttg taaaaattgt ggaaagataa tggaagctaa
    19501 agaagacctt ttagacaata tagaaaaaga gatacaatca ttgtacaaat ttaaaatact
    19561 tgatcatgat gttaaatttt atggactatg tgacgagtgt aatggagtaa gcgattcaga
    19621 agaataaact tctattgctt aatgtcgatg gaagaatagt atagaacttt tatattctat
    19681 gctattcttc cattttttat tataaaccat ctataaaatg caaatataca gttttcaaga
    19741 tacttatagt tttaatattg aaaatataat taatcctata agtacaaaaa tgaatgattt
    19801 ttctatgaaa ttactaaatg gtcctccaac agttaaaaaa cctaaagaaa ttttcttttc
    19861 gcttagcgga taaaaaattg gtattccttg ctttgtaaat aaatctccta aaaacatatg
    19921 acttgcataa ccaatcgtac cataaaaaga taaattatta atattagtga ttaattctat
    19981 ctgttttagt aaaaaatata ctattatagt tgcaaatatg ctatgagaaa aacttctgtg
    20041 ctttaaccag ggaaaaattg acaacattag acaaaaaatt gtaaaatata tttcaacttc
    20101 tatgatgtat aagcatatag ctaatagtat aaatattaat gatagaaaaa cttttcttag
    20161 aaatgtgtgg gttagttttg cttcaataat tataattgca ataaatgtaa ttattgcgct
    20221 taaataaaaa ttatcattta tatttattga aataaagaaa ataataatat taacagcata
    20281 tataaaaatt ctatatatgt atttggatac attgtttttt agaatgaaat ttgagaccat
    20341 agaattagat ttatccaaat cgggtagtac agcaaaagta gctgaaacta aaatatcaac
    20401 taaagatata ggaattttaa atattaaaga tgtttggata gctgttaaga ttcctattgc
    20461 acaatgagtt ttaccacgca taaatcctcc taaattatcc gatattaaat catataatat
    20521 ttagaggata tcaaaataaa ataggtttgt caaaataata cgttaaatgt attttaaata
    20581 tagcttaaaa tatgatacga attatggtac aataagaata actggtagcg agtgcgtgat
    20641 ttgatattat ttatgattgt agaacgtgtt aaaaaattaa atagacagaa ggagatgatg
    20701 caattgttca aaaagaacac caacaagata aaggtaatgg ccttgggtgg acttaacgaa
    20761 gttggaaaaa atatgactgt tgttgagtat aaagatgaaa taattgttat agatgctgga
    20821 cttagttttc cagaggatga aatgttagga gtagatatag ttataccaga tataacttat
    20881 ttagtaaaaa atagggataa aataaagggt atatttatta cacatggaca tgaagaccat
    20941 ataggagctc ttccatatat attaaagaaa ataaatgtac ctgtatatgg ggcaagactt
    21001 agtataggtc ttatacaagt aaaacttaaa gaacataaaa tgaataatgt taagttaaat
    21061 gttataggtc ctagacaagt tataaagctt gataatatgg aagtagagtt tttgaaaaat
    21121 aaccatagta taccagatgc ttactctatt gcaatacaca cagaccaagg tataatatac
    21181 cacacaggag attttaagat tgatttgact cctattgatg gagatgttat ggatatgcat
    21241 agaatctgtg agttgagcaa aaaaggagtt cttttaatgc tggcagatag tactaatgca
    21301 gaaaaaccag gatttactat gtctgaaaag actgttgggg taggtcttga cgaattattt
    21361 gcaaaaggaa atggcagaag aattatagtt gctacctttg catccaacat acacagatta
    21421 caacaaataa taaatactgc tgaaaagttt aatagaaaag ttgctatatc aggtcgctca
    21481 atggtcaatg tagttggagt tgcaaaagaa ttaggatact tagatatttc tgatgacatg
    21541 cttatagatt taaatgatat atgtaagtat gaagatagtg aattagtgat aataacaact
    21601 ggttcacaag gtgaacctat gtcagctctt gctagaatgg ctttttcaga gcacaaaaaa
    21661 gtagaaataa agagtggcga tttagttata atatctgctc atccaatacc aggaaatgaa
    21721 aaattaatat caagagtaat caatttctta tttgaaaaag gagcagaagt agtatacagt
    21781 gatatagctg atatacacgt ttctggacat gcctgtcaag aagaattaaa acttatacat
    21841 gcattagtta gaccaaaatt ttttatgcca gctcatggtg aatatagaat gttaaaaaga
    21901 catgctgaaa tagctgaaca gcttggtatg gataaagaaa atatttttgt catgcaaaca
    21961 ggagatgttt tagaattaga taaaaactct gctaaggtag caaaccgtat acaaacagga
    22021 aacatattag ttgatggtct aggagtaggc gatgtaggta atatagtttt aagggataga
    22081 aagcatttat cagaagatgg tcttatgata gttgtagtta ctatttccaa ggatgagggt
    22141 aaggtcttag caggtccaga tataatttcc agaggattcg tatatgtaag agagtcagaa
    22201 gatttaatgg atggagcaaa ggatataatt aagaatgttc taaatgaatg tgaagagaaa
    22261 aatattaaag aatgggctta tttaaagaat aatattaaag aaaacctaaa agaatattta
    22321 tatcaaaaaa ctaaacgaaa tccaatgata cttcctatca taatggaagt ataatataaa
    22381 aaaactataa atttgaaaat tagacctctt gtaattttta aagtaatatc aaaaatccaa
    22441 ttgatattat cttaagaatt acaagaggtc tttttaatac tcattttaaa aaaatatata
    22501 ttacataaaa taccaattat aacaatcttt tattagtaaa aactacttat atataaattt
    22561 tactgatagg aggattctta tggatgatgt ttcaagacaa aatgctataa aagctttaaa
    22621 acaaacaaaa atggaaatag caggagagta tggaatgaat tatgaagatg cttttgaaat
    22681 aatagaaaat gcgtctaata aaggtgtttt agaaggttac tttaaaaagc ttgaaaagaa
    22741 aaaaaattta ggtcaaggta tatctaggca tttagaataa aaaaagttaa atgtgagaaa
    22801 ataagtttaa ataaacttta agaggtgaca tcgatgaaaa aattagctag tactgctttg
    22861 gctatattaa ttgcgcttac tcctttaagc ttttcttttg caaataataa ggaaaatgct
    22921 gatgccaacc aactaaatat atcttcaaaa tcagcaattt tgatggatgt tggtagtgga
    22981 caaattttat atgaaaagga tgctcataaa aagcttcctc ctgctagtgt aactaaggta
    23041 atgactatgc tacttatagt agaagctttg gattcaggca agattaagct tgatgatgaa
    23101 gttcaagtaa gtgaaactgc atctagtatg ggtggtagtc aaatattcct agagccagga
    23161 gaaactcaaa aggttgatac attattaaaa ggtatagctg ttgcttctgc aaatgatgct
    23221 tgtgttgcta tggctgaaca cttagctgga agtgttgaag gatttgttga tagaatgaat
    23281 gctaaagcaa aagagttaaa tatgaatgat actcattttg caaatacaaa tggacttcca
    23341 gttgcaaacc actatacatc tgctcatgat atagctttaa tgtctagaga actattaaaa
    23401 cacgaaatta taagtaaata cttaactaca tggatggata aggttgtagt agggaagaaa
    23461 caagttacag taggtcttgc aaatactaat aaacttataa agcattatca aggagcaact
    23521 ggtgttaaaa ctggttttac tcaagaagca aaatactgtt tatcagcatc tgcaaagaga
    23581 ggtaatactc atctagttgc tgcaacttta ggagcagaga cttctccaga aagatttaat
    23641 gatgcctcta gccttttaaa ctatggattt gctaattatg aaagtgttaa gttatgtagt
    23701 aaaggtgata atatagcaac acttacattg gataaggctg atgaaaacaa agttaaattg
    23761 gttgctaaag aagatttaaa tgctcttatt aaaaaaggaa gttctaaaga atttgagaag
    23821 aaaattgaaa tagtaaaaaa tcctaagatg ccaattaaaa agggaactgt tttaggaaaa
    23881 ataaagatat gtaaagataa aaaagtaata ggcgaagtgg aattgataaa tactaaggat
    23941 ataaataagg caagctatct acaaatgctt caaagaataa ttgataatat gatataaata
    24001 attatcagat gaaatataat tataatacac aaagatatga ttataataca cataaaaaat
    24061 acccttatgt aattatttgc cataggggta tttttattta ccatatagaa gtattttata
    24121 atcttatgat ttttatagaa atatagaaaa gtttatgtat cttaaaatat catttgattt
    24181 aatatcatat atagggttgt ttaacaatta tctaagtaaa ggcatactac cagtaagttt
    24241 attcactttc tttttattcc cataaattgc tatcccaaaa tactgtaact catcttctgg
    24301 aacactagca atcttttgtg taaattcttc ataaagattg caactttgtg ctacatctga
    24361 aaaatctaca acagttaaat cgttaaattc caaagtatat aattttttac gtaaatcttt
    24421 tattatttct ttgtttcctt ttaaaatagg tacaggaatg tcaataattc ctaagtggct
    24481 attacctgtt ttgtcaatta catctgggcc aacagtttct ggggcatgtt ttcctagtgt
    24541 aattcccatt atagctgctg tattggatat aattcccatt ggtaaatttt cgtctattac
    24601 catgacacat tttgaatttt tagtttccat ttttatttct cctttttacc ttatttaaag
    24661 ttgtttgaat catcatttat aaatatattt tgatactgct ttggtgtaag accaataaaa
    24721 ttcttaaaaa agtttgtaaa gtgactttgg tctacaaatc ctgtttgtat cgcagcatct
    24781 ataggttcta cgcctttttc taaaagcttt ttagctttgt ttacccgtat attttctagg
    24841 tatctatatg gtgtaatacc ttttaatttc gtaaaattac gaagtagaga gtacttattc
    24901 atacctgcta tagtgcttaa ttcgtcaagt actatatgtt cagcataatt attttctaga
    24961 taatcacata ctgcttgaat ttctatattt gtattttcca agttagattg caaatttggc
    25021 tctgtatgtt cttcaattaa ttgttcaatt aggaagaaaa aaagctcttc ctttttaaaa
    25081 tccaattctt cttccatgat tatatagtgt aattcttgta gtagaggtac tagctcactg
    25141 ccaaatataa caggttgatt aaattttggt aaataatttt tacctgtaat ttcaaagacg
    25201 gtttttttca ttatttctgg cttaatatta atacatctgt aatcaagtac tttatcatct
    25261 atttgttcac aagtatgact atcaaaaggg ttaaaaagta gcaaatctcc agtacttgtg
    25321 gtatactctt tatttttaca agataaatat ctttgacctt tttctataaa accaattaca
    25381 taatgttcat gaaaatggtt tgggaatttt tgcattatgc ctttaaatct atatgcttca
    25441 atttttaatt ccctatcaaa gcatactgtg cgttcttctt gtctcactta agtaacctcc
    25501 tttcatgtta tacaaagtgt aacacatatt tttttatact tcttgtataa tattgactaa
    25561 gagacaataa tgtcaattca tgtcaatata atattatact tacagtaggt gtaattatta
    25621 tattttcaca atgaatatga tataataata aaagttataa aataaaaagc aaattttaat
    25681 tttatgccta gaagttaaaa ttattataat gtaaaataat tttgattata agctatttaa
    25741 ttgttataat aatattaaaa atttaattta ggagatgtac attaatgtta agtatgaata
    25801 taggagaaat agtagcaagt ttagttggta tagctatggc aatatcaata catgagtttg
    25861 gccatgctta ttcagctcac ttgttgggag atgatacagc taaagcttat ggtagaatga
    25921 cattaaatcc tgtaagacat gttgacccaa taggtctttt ggctatgttt atccttaaga
    25981 tagggtgggc aaagccagta ccagtaaatc caaataactt taaaaactat aagataggaa
    26041 acctgatagt ttcacttgca ggcgtttttt gtaatgtttt gactgctata ctgtgtgtaa
    26101 ttatcaataa gtatgtgcat atgtatgcta taaatacaat agctggatat gtgcttttat
    26161 atagtatggg atttgcagct tttaacttac ttccgatacc tccacttgat ggatggggag
    26221 ttatatctac atttgtacca tataaatgga atgaatattt gtataaattt gaaagtatga
    26281 gttatataat tttattaatt gctttattta ctggtatata tcaaataata ctatcaccaa
    26341 tatatacagt gttgctaaaa atagtatatt tatttgttta atataataaa cagattaaag
    26401 agggattgat atgaagtata atatacaatt acaagtctat gagggaccat tagatttact
    26461 ttatgattta ataacaaagc ataaaataga cataaaggat atatctataa tagatataac
    26521 taagcagtat ctaaattatt tgaaaatgct agataaaatg gatttagaga taactagtga
    26581 atttataact atggcatcaa aacttttaga gataaagtct aaatatctgc tttataagca
    26641 aaaagatgaa gaagaagacc caagaataga acttatggaa aagttagaag aatatagaaa
    26701 gtttaaggta gcatcacaag atataaaaga aaatataact tatgttaatg agagatttta
    26761 tagaaataaa gaagagataa ttattgatga caatgtggat ttagaagata tatcaataga
    26821 agcaataaaa aatatacttc catacatatt taaagttaaa acatcacaga tagaaaatgc
    26881 taatgatgag aaactagata aaatagtaag gaagaaaata atatctgtag aagaaaaaat
    26941 attatatata agagatatta taaaagataa gattgaagtt acttttacaa atattataaa
    27001 atcatatgaa aatgatgaaa taatagctac ttttttatct atattagagc ttataaaaga
    27061 aaaagaaata gtcgtagtac aagatatatt ttttgatgat attctaataa gaaaaagttc
    27121 ggagtgttaa aatgaaaaga gaagatataa agtatattat agaatctgtt atgtttgcat
    27181 atggtgagcc aataagtata aaagaattaa actatataat aaataaagaa ctttcatcaa
    27241 aagaaataga gattatgtta aatttactta ttgaggagta cagagaacaa aatagaggta
    27301 ttcaaataat caagttagag aataagtacc aaatgtgtac aaataaagac tatgcagaat
    27361 atataaagaa gattattgaa ccaaagaaaa agaaaagttt gagccaagct acattagaaa
    27421 ctcttactat aattgcctac aaacaaccaa taacaaaggt agaaatagag gatataagag
    27481 gagtaaaatg tgataaggta ttacaaactt tgtttgaaaa tgaacttata agagaagctg
    27541 gtagattgaa taagataggg aaaccaataa tttataaaac aacagatgaa tttttaaagt
    27601 tgttgaatat agaaagtctt gaagaattgc cacctataga aaattatcaa gaagtggcaa
    27661 caaatgaata aaaatataaa atcacaat
//
LOCUS       DAGQVA010000051        27073 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.051, whole genome shotgun sequence.
ACCESSION   DAGQVA010000051 DAGQVA010000000
VERSION     DAGQVA010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27073
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.051"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            573..1901
                     /locus_tag="MIV85_002452"
     CDS             573..1901
                     /locus_tag="MIV85_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBY2961782.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2654..3487
                     /locus_tag="MIV85_002453"
     CDS             2654..3487
                     /locus_tag="MIV85_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBY2961783.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3580..4512
                     /locus_tag="MIV85_002454"
     CDS             3580..4512
                     /locus_tag="MIV85_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBY2961784.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEVLKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4564..5046
                     /locus_tag="MIV85_002455"
     CDS             4564..5046
                     /locus_tag="MIV85_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2961785.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQESMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            5058..5927
                     /locus_tag="MIV85_002456"
     CDS             5058..5927
                     /locus_tag="MIV85_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBY2961786.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIRAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5970..6725
                     /locus_tag="MIV85_002457"
     CDS             5970..6725
                     /locus_tag="MIV85_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBY2961787.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSITKIKGLKDKTLENKLNNELLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSIYIKTISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6767..7588
                     /locus_tag="MIV85_002458"
     CDS             6767..7588
                     /locus_tag="MIV85_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBY2961788.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7593..8354
                     /locus_tag="MIV85_002459"
     CDS             7593..8354
                     /locus_tag="MIV85_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBY2961789.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKYKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSDCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8515..8772
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8885..9124
                     /locus_tag="MIV85_002460"
     CDS             8885..9124
                     /locus_tag="MIV85_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBY2961790.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9428..10423
                     /gene="ilvC"
                     /locus_tag="MIV85_002461"
     CDS             9428..10423
                     /gene="ilvC"
                     /locus_tag="MIV85_002461"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBY2961791.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDHT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10476..12164
                     /gene="ilvB"
                     /locus_tag="MIV85_002462"
     CDS             10476..12164
                     /gene="ilvB"
                     /locus_tag="MIV85_002462"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBY2961792.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSIEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(12525..13655)
                     /locus_tag="MIV85_002463"
     CDS             complement(12525..13655)
                     /locus_tag="MIV85_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBY2961793.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINKKYKDDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKVKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVKHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(13895..14401)
                     /locus_tag="MIV85_002464"
     CDS             complement(13895..14401)
                     /locus_tag="MIV85_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBY2961794.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
     gene            complement(14664..16253)
                     /locus_tag="MIV85_002465"
     CDS             complement(14664..16253)
                     /locus_tag="MIV85_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBY2961795.1"
                     /translation="MKSIISDVINRFNATPFLFVGSGLTRRYYNLPNWEDLLKVFAEK
                     ISNDDFIYTSYKNKAKSENPKMGINPRIAELIENDFNKKWFSDSSIRSLDSKYLDIVK
                     SGVSPFKAEIAMYIKNNSKIVDKYQDEVEKLSNISKKSLSGFITTNYDCFLETIVDNY
                     TTYIGQENLVFSSIQGIAEIYKIHGCVSSPNSIVINEADYIDFDSKSAYLAAKLMTIF
                     VEFPIIFIGYSVTDVNIKKILNAIVNCLSNENAKKLEERFIFIEYEKNFNDIEISSHT
                     IVFDNKMITMTKIKLEDFNLLYEALSEKKSKLPVRILRMFKQEFYDFTITNKPTAKIR
                     VGSVDDTRIKDEDLVLAVGKASDFGLKGLKGLSFDEWYRDIVMNDLEFSSDELLEYAY
                     PSLIKQYNKLPLNKHLFNSTLEFPDYRTIALESDFENIISNSIKKNRNNTYIKNRSVY
                     GIWNDEHQSFEKATRLIAFLEEKEIDTEQLENLLKKIFEENPNILESAKTSEKTNLRR
                     LIRIYDYMKYSNMQKSLGYSE"
     gene            complement(16277..16840)
                     /locus_tag="MIV85_002466"
     CDS             complement(16277..16840)
                     /locus_tag="MIV85_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBY2961796.1"
                     /translation="MSILSDRLKFLRKEKGVMQKEIANYLNITTSAYGFYEQGKRTPT
                     PEMLSSLAEYFGTTVDYLIGRYDNKASNISSKTSCNNTLFQKRLKELRAEKNMTQEDV
                     ANKLNLTKSAYGYYEQGKTVPDAYMLSSLAEIFNVTTDYLLGRSIVKNDIDTVAAHRV
                     NPHKDLPEEAQEQLNDYIEFLINKYKK"
     gene            16993..17214
                     /locus_tag="MIV85_002467"
     CDS             16993..17214
                     /locus_tag="MIV85_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961797.1"
                     /translation="MNNLKELRTERNLKQKDVALKVGITTSYYGMIESGTRVPSLAIA
                     IKLSKCFGVSIEKIFLNTNTTRCCLKERS"
     gene            17217..18032
                     /locus_tag="MIV85_002468"
     CDS             17217..18032
                     /locus_tag="MIV85_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein/antirepressor Ant"
                     /protein_id="HBY2961798.1"
                     /translation="MKDLKIVKVNNKLTTDSRDIALMVEKEHKILLRDIRNYINQMEE
                     ANKNMSTDLYPSDYFIENTYLDDYKREKPCYAITKIGCDFIANKMTGIKGTAFTGIYT
                     KKFEEMEQVLKNEQPKLPTTYKEALQHLIEQVEVNEKLQLEGKMKDQVIKELKPKADY
                     TDMILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHS
                     ETIDITRSDGMTDVKMTTKWTQKGRLFLYDLLKVNNILPDIEKEYSYQTSMLC"
     gene            complement(18211..18390)
                     /locus_tag="MIV85_002469"
     CDS             complement(18211..18390)
                     /locus_tag="MIV85_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBY2961799.1"
                     /translation="MSTSLPKYTLRINRVLLEKIKYIAESEGRSANKEIEQIIKKHIE
                     DYEQRKGEIKINIEE"
     gene            18526..18705
                     /locus_tag="MIV85_002470"
     CDS             18526..18705
                     /locus_tag="MIV85_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961800.1"
                     /translation="MNSNKKRITVRMPEKLNEEITKKSKYLGLTKNSFILDILWKEFE
                     LLEYRSYKKEVDKHE"
     gene            18698..19489
                     /locus_tag="MIV85_002471"
     CDS             18698..19489
                     /locus_tag="MIV85_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBY2961801.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDSRNISNNFNNNKDKFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFASKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EETYFKVKQHKPTCIEDVLIESLKEMKDLRLQVNQANSIALEAKTEVETIKDVVSLDS
                     NSWRTNTHQLIARIAKKQGGFEHINMLRTESYELLNKRFGVDLHRRLINKRRKMAEEG
                     VSESKREKVNNLDVIQDDKKLIEGYVAIVKDMALKYGISSDLSKN"
     gene            complement(19572..19766)
                     /locus_tag="MIV85_002472"
     CDS             complement(19572..19766)
                     /locus_tag="MIV85_002472"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961802.1"
                     /translation="MKFVYVKIFNNWIDITDIGSINGCNAIEYINENLDKMYSSNYVS
                     INYKDKNYCIHPSCIQIVTK"
     gene            complement(19922..20140)
                     /locus_tag="MIV85_002473"
     CDS             complement(19922..20140)
                     /locus_tag="MIV85_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961803.1"
                     /translation="MTKFKDNIKLVRKQMNMTQKQFASLFGISERAYQYYEAGSREPN
                     LETLILISNKLNVSTDFLLGLSPNQNRN"
     gene            20253..20447
                     /locus_tag="MIV85_002474"
     CDS             20253..20447
                     /locus_tag="MIV85_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961804.1"
                     /translation="MKINNNLKLQREKIGLTQLEVAQKAKITERSYQYYEAGERLPNI
                     RTALKIAIILNTNCEKLFNE"
     gene            20489..21283
                     /locus_tag="MIV85_002475"
     CDS             20489..21283
                     /locus_tag="MIV85_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBY2961805.1"
                     /translation="MNNLQLNNKNTITTLEIADMLEIRHWEVLRKLEGTEKTKGIIDI
                     LNDNNFVVVDYFIKSTYLDSKNESRPCYNVTKLGCDFLANKFTGEKGIIFTARYVRRF
                     NEMERVLKEQQPKLPTTYKEALQQLLVEVEEKEQLQLENQEKDKVIQLQQPKVLFADA
                     VSASNNSILVGELAKLIKQNGVDIGQNRLFTWMRENGYLIKRKGEDYNIPTQKSMNLR
                     IMEVKKRVINNPDGSTKVTRTVKITGKGQVYFVNKFKSSKQLSMLS"
     gene            21340..21549
                     /locus_tag="MIV85_002476"
     CDS             21340..21549
                     /locus_tag="MIV85_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961806.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(21559..21933)
                     /locus_tag="MIV85_002477"
     CDS             complement(21559..21933)
                     /locus_tag="MIV85_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961807.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            22009..22206
                     /locus_tag="MIV85_002478"
     CDS             22009..22206
                     /locus_tag="MIV85_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961808.1"
                     /translation="MLIGDNIKQILRKRDIKPYKLAKELNIDVSGLYKLLKNKNSNPT
                     IDTLIKLADYLDITLDELVGR"
     gene            22237..22629
                     /locus_tag="MIV85_002479"
     CDS             22237..22629
                     /locus_tag="MIV85_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2961809.1"
                     /translation="MDISESITKQFSDSLKSLIEIEINKQETDRVKSQTVEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTVFMRRLVSTGLIKSLARGDGRKISRYEV
                     DDFIERNQGKNLDELLKVAERGDEIVKP"
     gene            22616..22759
                     /locus_tag="MIV85_002480"
     CDS             22616..22759
                     /locus_tag="MIV85_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961810.1"
                     /translation="MLSLNTNKNNIVTLKKDGKAIADIVFKDIKTGKKISVGVLNKKV
                     LVK"
     gene            22926..23168
                     /locus_tag="MIV85_002481"
     CDS             22926..23168
                     /locus_tag="MIV85_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961811.1"
                     /translation="MEAARLIAIGQIKQAEKEICKLQGTKNNSSLMWWEAVKFASQNI
                     LEGLEHDIELEASIEFREAMMYQEELEKDRPIDVQI"
     gene            23247..23528
                     /locus_tag="MIV85_002482"
     CDS             23247..23528
                     /locus_tag="MIV85_002482"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961812.1"
                     /translation="MKTKNEIIKGLEDRLFLLRFTTVDEVDWDVKFGQISALEFCIDK
                     HRKGCTLEQFKEHLDEYKLQGNYGDYIDGFVSVLERNIREMEGEIDGSE"
     gene            23515..24153
                     /locus_tag="MIV85_002483"
     CDS             23515..24153
                     /locus_tag="MIV85_002483"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBY2961813.1"
                     /translation="MEVNNIYIKLMDVRIKFNKLDIKKSGQNKFANFKYFELADFLPQ
                     ATELLQEAKLCPIVTFTNDYATLTLINGEKPTEEIIFTSPMRELQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITENDTFDATSGKEDYKRNDLTNSSIKASENGQIKISQNQIKRL
                     FSIGNTIGKDSDRVKSEVYYKFNKEVKDLSKQEYDQICVGYEKLQREKGIIK"
     gene            24163..25059
                     /locus_tag="MIV85_002484"
     CDS             24163..25059
                     /locus_tag="MIV85_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBY2961814.1"
                     /translation="MKDRDKATIEKGNILSDGYGLSPQLVARDSWLTTGARALYFYLS
                     SFAGASGTCYPSRDIMTHELGINKDTFSKYLNELKTSGYIKVYKNKTREGRMQNNIYE
                     VVFDRSYIESHISIRCKKENKKKPCPKKADMEPCPNLPDMVQPDMEKSDTISNSIINN
                     SFKSSMYIEQAVDNSLKEFKKLYEENIGVVYPVTAEWLLEVSNEVDIRVFKRAIEICA
                     ERMNMNLSYLKGILKKWKDANITTYEQLESYKLQHENKKSKKTNSVVSKNKFANFEQT
                     FTQYSNKELDEIIKKSQKAKFK"
     gene            25079..25498
                     /gene="ssb"
                     /locus_tag="MIV85_002485"
     CDS             25079..25498
                     /gene="ssb"
                     /locus_tag="MIV85_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBY2961815.1"
                     /translation="MNQVVLVGRLTRDPELKYIPGTGTAVASFTIAVDRNYINKEGKR
                     DTDFIPIEVIGKSAEYCANYITKGKLVALEGNIRVDNYQTQSGEKRIFTKVSTKSVQS
                     LESKNKSSNSYKESVQDGTIGLDPQGFEIIDDDELPF"
     gene            25528..25890
                     /locus_tag="MIV85_002486"
     CDS             25528..25890
                     /locus_tag="MIV85_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961816.1"
                     /translation="MFKVERYFSGSVVDNLIEDDLTCRNYLALYCCLLGITKNGKKIY
                     PKPEKMLAEFGVKKDRKIKKELPVRIRNVNTGEVKEFESIDGAACFLRLKYQAVYQAI
                     KKKTKTRSGWKVEYIKEE"
     gene            26124..26975
                     /locus_tag="MIV85_002487"
     CDS             26124..26975
                     /locus_tag="MIV85_002487"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBY2961817.1"
                     /translation="MNVLSLFDGISCGQVAFERARIKVENYFASEIKEIAIKVAMNNY
                     PKTIQLGDVRELNVSKIPKVDILIGGSPCQNLSKGRLIANKIQDGLTGDKSNLFWEYI
                     RILKQLNPEYFLLENVVMPKKDENMISQLLGVEPIKINSNLVSYQNRDRLYWTNILNV
                     QQPKDLKISFQDYKDTSFDYCKEFEIKKTPSREKMWGNGLNGNCKNVTYEDKINCVTL
                     KQDRFSNSGLVEFGSFCRYLTTRELELAQTLPVGYTKGLSIRQAQNVIGDGWTIDVIA
                     HILSNIN"
BASE COUNT        10970 a         2892 c         4521 g         8690 t
ORIGIN      
        1 aatatgaatg aaagtagtgg gttttataaa aaaacatatt tagattttaa catctaaaag
       61 gagttttcaa agctaatatt tcatttttaa ataaaaaaat aaaatattag ttttgatttc
      121 tggtttaaat tgggttataa taaattgtca aattatttat taatataaaa tagactataa
      181 aacaagcaaa aatcatacta ttatataaaa gaccttaaag atagaaaact acagaaagaa
      241 gccaaaatgt ttttgaaaaa aatgaaattt tattgcaaaa aaatcaaaat gaatttaact
      301 taatagttat aatctatttt tagtgttaca aatatacaat gtatattata caatataaaa
      361 aatacattta cttagaagta ttattatatt tggatttttg gtttttataa tttttttata
      421 tttaaacata gctaaaaata aaagattacg aaagctaagt agagtttatt ttattttaat
      481 aaataataaa gctatttttc tatatattgg cataatatat gcttatttaa ctatgaaatt
      541 aaaattaaat aggattaatg aggaggaaaa aaatgggaag taatgaactg aaaaagactc
      601 ttggcgtatc agcagcatta tcaactgttg ttggttccgt tataggagcg ggcgtatttt
      661 ttaaaccaca agcagtctat acattaactg gaggagctcc aggtcttggt atattggcat
      721 ggttaatagc tggaatcata actataacag ctggtcttac agctgcagag gtatcagttg
      781 cgataccaaa aactggtgga atgatggtat atataaaaga aatttatgga gaaaaattag
      841 gttttttaac tggatggatg caaattgtat tattttatcc agggatgatg gcagcattag
      901 gtgttatatt tggagaacaa gcatcagcac taattggtag tccatcactt ttacttccaa
      961 tagcaattgg aattatagta atagttgcag ggcttaatat gttaggttca aaaactggag
     1021 gagtcataca aactgtttct acaatttgta agttaatacc acttatttta ataatggttg
     1081 ttggatttat taaaggtggt ggaaataatc caatacttac acctatggtt ggtgaaggat
     1141 taagcctggg tagtgtacta ggtcaagttt taattgctat attatttgct tttgatggat
     1201 ggatgaatgt tggtacttta gctggagaaa tgaagaatcc tggaaaagac cttccaaaag
     1261 ctataatagg tggattgtca gttgttatgg ctgtttattt tataataaat ttagcgtatc
     1321 tttgggtatt accagctaat gaattagcaa attatgcttc tcctgcatca gcagttgctg
     1381 aagttatatt tggttcaatg ggtggaaaaa taatatctgt aggtatatta atttcagtgt
     1441 ttggagcatt aaatggattt ttactaactg gttcaagggt ggcatatact ttagctacag
     1501 ataagacttt accaaagtat ggtatatttt ctaaattaaa ttctgctcaa gttccagcaa
     1561 atgcaatagc attagtatct gttattgcat ctatatatgc tttgtcaggt caatttaatt
     1621 tattaactga cttagctgta tttgctactt ggatattcta tgtattaact tttatagggg
     1681 ttatgaaact tagaaagact catccaaata taccaagaga gtataaagtt ccattatatc
     1741 ctattgttcc tataatagct atagcaagtg gtatatttgt tgtagttaat caattgtgtt
     1801 ttgcaggtat gaaaactact atgatatcta taggaggtct tgtaataaca gctataggct
     1861 taccagtgta tgcttatatg actagaggag taaaaagata aaccaagtag tttacaaatg
     1921 cttcataatt aaaataaaag agactgtctc aaatagagat aagtctcttt tttattgtta
     1981 aaatggtaaa gatatgttta attttacaaa aaaagagcgt tccatgaact aaaaagttta
     2041 ttttaaggta ttcattttat ttttagtttt ttgattataa aattaaacat ctaaaaaatt
     2101 atttatttta aaatacttta ttttaaagtg ttttttatca aactaagtgg tatctgtaca
     2161 acaaatatta tacatagctt ttatgaaaat taaatctttc tgttatatat aatagaatat
     2221 tgtattatat agaaaatatt acctgattaa tatagtgatt tataaatgag attagaaaat
     2281 tttatttgat aacaaaaatt agataatatg aatatataat gtatgtatta aaaatgtggc
     2341 aaatagttgt tttgctattt attatttgtt taatatttct aatttataaa aaaaaaatta
     2401 taaattttaa aaattataaa tgacatttta actagaatta attgtaaaaa acactatata
     2461 atactcaatt ttcaacattc tatacaatta tacagaaatt atacagcata ataatcaccg
     2521 aaataacaaa ttttaaaaat taagcaaaac tttttgtcga agttcaacgt ctatatatat
     2581 gtagtgtaaa tttttgggat aaaatactac aaaaatataa atgtaaaaat atagtaatat
     2641 tggaggtcga acgatgagaa ataaaaagaa aaaaataaat agaaagaagt tgtatttgct
     2701 tttaagtgct attgtagtgt gtctggcttt tatagtagtt ggtgttcgcg tcagctcttt
     2761 aaatatgaag gaaaatgaaa ttagtagaaa tgcaaaactg tcaagttcta ctattacaga
     2821 tatagtatct aatacatcaa tagaagttag taaagggcca agtaaaagtt ctggaaaaat
     2881 agcatacata actatagatg atggtccatc taaatttact gacgagatga taaaaacttt
     2941 aaataaatac aatgttaaag caactttttt tatgatagat gggaatatga aggaatatcc
     3001 acagcaagtt aaaaatataa ttaaaaatgg gaacacagca ggttttcata gtgtatcaca
     3061 tgatattcac aagctttatg ttactagtac atcagcaaaa gaggaatttg atacaaatga
     3121 tcaaactttt tataagataa ctggtaaaca ttcaaaagta ataagaatac cttatggaag
     3181 caaaccatat acaccacaag cctcttatca ggctttagtt gatgctggat ataaaatttg
     3241 ggactgggac ttagatacag aagactggag atctaattct tctcaaattg tacaaaatgt
     3301 aaaaaatcat attaagaata gaaaaggtga agataaagac caacttgtag ttttaatgca
     3361 tgagaaaaaa cagagtgcag aagctttaga ttcagtttta aaattcttat cagatgaagg
     3421 ttatgaattt gcgccagtag atcaaaacca aataccaaaa aattattggt tacgtaattt
     3481 agagtagtta aaatataaga atattgattg atatttttag aaattgagaa taaaaatgag
     3541 tgaggtgtag gtatattgaa taaaaaaatt tatataggaa tggtcggaat attgtctttg
     3601 atgatggttg gttgtaataa aagtttagca aaagtaaatg atgtggaaat cacaaaagaa
     3661 cagtacaaaa aaacaaaagc agttttatct gctactaata attatataaa tgggcagtct
     3721 ttagatgaat tagaaaaaac tttggataaa aaaggtagaa ataaattaga aaatgttata
     3781 atatcgttta tggtggataa tgaactttta tatcaagagg ctaaggataa aggactaact
     3841 ccaagtaaaa gtgaagtaga ctcaaaatat caagaactag aagataagat gaatttgaat
     3901 acaagctata aggaaaaaat ggacaaagca ggtgttgata aagattattt aaaacaagaa
     3961 atatctagag atttagcaat agataaaaat aaaaaggcct ttgaagatag aataaacata
     4021 agtgataatg atatggaagc ctactataca agtcataaaa aagattttaa tgtagaagaa
     4081 gtaagtgctt ctcagatact tatatcgact ttagataaaa ataaaaaaga agtaagcaaa
     4141 gataaaaaag aagttttgaa gaagaaggca gataatatat tgactaaaat caaaaatgga
     4201 gaaagttttg aaagtttggc taaaaaatat tcggatgata aagcaactgg aaaaaatgga
     4261 ggacagctag gatattttac aaaggatgat aaaaatgctg agtttacaaa ggaagtgttc
     4321 aaattaaaga aaaatgaagt ttcaaatgtg tttgaaacta gttatggata tcatatagtc
     4381 aaagttactg ataaaagaga aagacaaaaa agttttaatg agtgtcagag tttaataaga
     4441 gaatctattt taaatgaaaa gtatattgag catataaaaa aactgaatga agatgctaaa
     4501 atagacagat agaatttcta acagctcaat cctagcctgt aatcggaggg agattttaca
     4561 ggaatgttta agagtttaaa gagaacgaaa gttgagaaat acattatcga taataaagac
     4621 tctttttata gaatagcata tagttatacg aagaatgaag aagatgcctt agatgtggtt
     4681 caagaatcca tgtataaggc actatactca gtggaaaata ttaaagaagt aaattatata
     4741 aagacatggt tttataaaat tttagttaga acgagtatag attttattag aaaaaaccgt
     4801 aaatataata atatgacaga tattgacctt atagatgaga ctggagagta tgataaatat
     4861 actgatttgg atttaagaag agctttggaa gaattaccta ttgaatacaa atctattata
     4921 atattaagat tttttgaaga tttaaagatt gaagaagtag caataatatt ggatgaaaat
     4981 gtgaatactg ttaaaactag gttatatact gctttaaaaa aactaaaatt aaaaattgaa
     5041 gagtagggat aaaaagaatg acaagcaaag aaaggttaaa taagttaaaa gatgagtatc
     5101 ataaaattcc aatacccaag aaattagata ctataataaa tcatgaaaaa atagaaaaca
     5161 tatatcgaga gaaaaataaa aaagtaaata gattaagatt taaagttgca atagcctttg
     5221 catgtatatt tacagtatta gtaaatataa gtcctgtatt tgcagacaat ttttctaaga
     5281 tacctgtaat tagagcaata gtagaagtaa taactataaa aaattatagt ttaaaaagtg
     5341 aaaattatga agctgagatt gatattccta aaatacgagg tttaaaagat aaaaacttag
     5401 aacaaagatt aaacagtagt tttatggaag atggaaaaag actttatcat caattccaag
     5461 agagaatgga gaagatacaa tcatcaaaga ataaaggata taaatcttta agtttgagtt
     5521 atagtgtaaa aaataattct aaaaaatttc tatcaataga gatgacaaaa aatgagatag
     5581 aggcttcatc atatgtgagt aaggtacatt atactattga taaaaaaaga caaatagttt
     5641 tgactttgcc aatgcttttt aaagatgata agtatataaa agttataagt gataatataa
     5701 aagaacaaat gagagaacaa atgaaaaagg atagtacaaa atcctatttt atagatcaaa
     5761 aaaaagactt gcctgttgaa gattttaaaa caattaataa gtatcaggat ttttatttta
     5821 ataaaaatga agaccttgta atttgttttg atgaatatga agtagcacct ggttatatgg
     5881 gcgcagttga gtttgtaata ccatataaag taataaaaga tttgtaaatt gaatagtagt
     5941 ttatatataa atcttttaag gaggacaata tgactacata taaaaaactt aaaaaatcta
     6001 tatttaaaat tgctatattt tcaatatgct tattagtttc attagtagat acaaacccta
     6061 tatttgcagg tagctccttt aatgaaactt caaatagtga tacgataaag gtgttaaatg
     6121 ctaagagtat caactttaaa caagacaatt atgaagtgaa tgtgagtatt actaaaataa
     6181 aaggtttaaa agataaaact ttagagaata aattaaacaa tgagcttttg caagatggga
     6241 aaaaaattta cagtgaattt caaaataaaa tgaaaaagga aaataataag ggtcatagat
     6301 acctaaatgt aatccataat gtcaaaaata attctaagga ctttttatca atagaaatga
     6361 caaaagaaga gatagaagct tcctcatcta taactaagaa gcattacact gttgataaaa
     6421 atagaggaat actattaaat ttaccaatat tttttaaaga tagtatatat attaaaacta
     6481 taagtgataa tataaaagag cagatgagaa atcaaattaa gaaagatgat acaaaatctt
     6541 attttataga ccaagataaa gactccccag tgaaagattt tgaatctata aataagtatc
     6601 aagattttta ttttaataaa aatggaaatc ttgtgattag ttttgatgaa tatgaagtag
     6661 cacctggtta tatgggagca gtagaatttg tgataccaaa taaagtaata aaaagactaa
     6721 gatagatata tagaagattt ttagatagac tggtaaggag aattatatga atatatatga
     6781 acaagcaata agattaatag aaaataatga ggatttcgca tttgctacaa taacgtctca
     6841 ttcaggttca acaccacgtg aaactggagc aatgatgatt gtgaaaaatg attctactat
     6901 atttggctca gtaggaggag gtagtgtaga agcagaatgt ataaaacatg caattaatgt
     6961 tataaaaaac agagaatcaa tgttgtataa atttactcta aacaaatctg atgtggcaaa
     7021 actaggaatg atatgtggag gtactggaga aatacaaata gattttatag atagtaaatt
     7081 aaaaagtaat atagaaaaat ttaataagag actaaaggaa aatacaagta aagcatatat
     7141 atttggtgca ggtcatattt caagagatgt tgctgtgata ctatctcttt tagaatttag
     7201 aacagtagta atagatgata gagaagaatt tgctaatcat gaaaggtttc cagaatcaga
     7261 agtagtagtt ttagattctt ttgaaaacat accagatttt ccaactgacg aaaatagtta
     7321 tataattatt ttaacaagag gtcatctata tgattcaagt gctttagaat gggctcttaa
     7381 aagagaggct ggttatatag gtatgattgg aagtagaaca aaaattggat tgacttacga
     7441 aaaactcatg aaaaaaggtt ttaagaagga agaattatca aaagtacatg caccaatagg
     7501 cataaaattg aatgctcaaa caccagctga aatagctgta tgtatagctg ctgaacttat
     7561 aaattgtaga gctaataagg aaaaataaac taatgaacac agggagtaaa gatattgata
     7621 ctttaaaggt taattttaga gggattgaaa taaaagcagt tttagtatat aaaaatagaa
     7681 aaaatatttc tataaaaata gatccatttg gcaaaataac tgtaatgagt cctcctaaaa
     7741 tatccaaaaa aataataaaa gatataatta ttgaaaaagg agactggata cttaaaaagt
     7801 cagaaaaata taaaggaaga gaggaagtat ataaacaaag aatgtttata actggcgaaa
     7861 aatttcttta tttaggtgaa gagtaccatc tagttataaa agaactgttg agagattctg
     7921 tcaaaaaaag tgactgtaga ataactatta acgaatatca aatagttgtt cagacaaatg
     7981 atacaagtac agattttatt aaaaaatctt taaaatcttg gtataagatg gaaagtgaaa
     8041 gaatagtatt agagagaata gattttctta aattaaattg tgaaataatg aagcaattag
     8101 ttccagcgag tgttaaggta aaagaacaaa ataagagatg gggaagttgt acagctcaaa
     8161 aaaatattta tataaactca aaaatatcta tggcaagatt agatgtaatt gattatgtaa
     8221 taatacatga gtttagccat ttagtacata tgaatcactc taaaaaattc tatgatttag
     8281 taaaatccat tatgcccgat tataaagata aagaaaattg gctaaaaata aatggatata
     8341 aaataataat ctgaaaacga ttattccaaa atataggcgt aaagtataaa agaagtatta
     8401 ttatgaaaaa aataaataat ctgaaaattt taaaaaaagt cattgacatt gtaaatgata
     8461 gggaatataa tctatattaa caacaaaaca gaattaaaat ataaaattaa aaaattaaaa
     8521 gcaatgacag agacaacaat actaatagtg ttatccacag agaaccaatg ttgctgagaa
     8581 ttggtgttaa cagtagtata atgatcactc tggagctttt gtactgaata tttttagtaa
     8641 gtacaaacgt atgtcaacgt tacatgacta aggttaaggt aattaattac ccgacctgaa
     8701 aaaagagggg tagatgtatt ttttatatct acaaataagg tggtaccgcg gaatataact
     8761 ttcgtcctta taagtaatat ttatattgct tataaagatg aaagtttttt tattttaagc
     8821 gatataaata aatttaatcc atataaaatt aataaaaaaa taataaaaat aaggagggat
     8881 ttttatggaa aatactgtat atgctaaatt aaaccaagga atagattctt ttttaagagt
     8941 ggctatgact ctaagaagaa gagaggttga tatacaatca ataagtatga ctgtagataa
     9001 tatgaataat tcaggtataa aattaatagt aaatgaagaa aagacatctt tagattctgt
     9061 cttaaaccat atgaaaaaac tacatgatat aagagagata actgttgaaa gaatgagaca
     9121 ttaattaaat atattttata aaactaaaga taaatatgct tattttaaaa taaaaaacta
     9181 aagataaata ttaaataaga aaaatcttag attaaaatat aagtgtcatt gaatttatta
     9241 gtttatcaca gttaataaat ttattagttt gttgtagcta ataaaaactg aaaattctaa
     9301 aattataatt gtaagattat ataaatttag aatttaaatc tgttgaataa tattaaaaca
     9361 atgataatga gtatgaattt ctaataaaaa taaatatcat aaaaataaga aaaagtattg
     9421 ggaggaaatg aaaatggcaa gaatgtatta tgaaaaagat gtggatttag aggttttaaa
     9481 aaataaaaag gttgcagttt taggttatgg aagtcaagga catgcacatg cacaaaatct
     9541 tagagataac ggtgtacatg taatgatagg tctttatgac ggaagtaaat cagcacaaaa
     9601 agcaaaagaa gatggatttg aagttaagag tgtagcagaa gctacaaaag aaagtgattt
     9661 gacaatgatg ttaatgcctg atgaaaaaca aaagaaagtt tatgaagaga gtgtaaagga
     9721 taacttaaaa gaaggtcaga cattagcttt tgctcatgga ttcaatatac attataatca
     9781 agtacaacca ccagaatttg ttgatgttgt aatggtagct cctaaaggac ctggtcactt
     9841 agttagaaat gtatttacaa agggaagtgg agttcctgca ctatttgcag tatatcaaga
     9901 ccacactaaa aaagctacag agacagtttt agcatatgca aaagggatag gagcaacaag
     9961 agcaggtgtt ttagaaacta cttttaaaga agaaacagaa acagatttat ttggagaaca
    10021 atcagtactt tgtggtggaa taagtgaact tataaaattg ggatataaaa cgcttgtaga
    10081 tgcaggttat caaaaagaag tagcatattt tgaatgttta catgaaatga aactaatagt
    10141 cgaccttata tatgaaggtg gatttgaaag aatgagatat agtataagtg acacagcaga
    10201 atatggagat tatgtatctg gtaaaagagt aataactgat gctgcaaaac aaggtatgca
    10261 aaatgtttta gaggatatac aaaatggaaa atttgcaaaa gcgtggatta aagaaaatga
    10321 agaaggacgt gaaaacttcc taaaaactag agaagaagaa tataatacag aaattgctga
    10381 agttggtaga aatctaagaa gtatgatgtc attcttaaaa taaatatata ttaaatggat
    10441 tagtttgagg gaaagagtgg tgtatagtag tgcgtatgaa tggagcaaag gtaattttag
    10501 aatgtttaaa gaaagaggga attgacacaa tatttggata tcctggtgga gccgtgatac
    10561 ctctttatga tgctctatac gattattcag atgattttaa acatataagg acatcccatg
    10621 aacaaggttt agttcatgct gcagatgggt acgcaagaag tactaataca gtaggagttt
    10681 gttttacaac atctggtcca ggagcaacaa atgccataac tggaatagca acagctttta
    10741 tggattcttc acctatggtt gtaatttcag ggcaggtgcc aactagttta ttaggaaaag
    10801 attcttttca agaaattgac ataactggag caacattatc tatgacaaaa cataattatt
    10861 tagttagaaa cactaaagaa ttagttccta caataaaaga agcttttaga gttgcaaatt
    10921 caggtagaaa aggacctgta cttgtagatg ttccaaaaga tttattttta gcagaaatgg
    10981 attttagtgg tgaggactat gatttatgtc aaatagatga ttatatggat tataagagtg
    11041 attttgatct agatgatgaa actaatatta agcttttaaa tgaagcaata gatatcataa
    11101 aagaatctaa aaagcctgta atatatgcag gtggaggtgt taaatcttca gacagtgagg
    11161 aaattcttga aaaatttgca actaagatag atacacccgt actaaataca cttatggggc
    11221 ttggaaatat agatagaaag aatgaactat ctcttggaat ggttggaatg catggaagta
    11281 gagaaagtaa tttagcactt tctaattcag atttagtaat agcgataggt gcgagattta
    11341 gtgatagagt gataagtaaa agttctgaat ttgctaaaaa tgcaaaaata atacacatag
    11401 acatagaccc atctgaaata agtaaaaata tagaatctaa tgtatctttg gttggagatg
    11461 taaagctagt ccttagttta ttaattgaaa gggttgaaag taagaataat agcaattgga
    11521 aagaagagat aaagagattt agaaagagtg agggtgtaca aacatatgaa tttcatccac
    11581 aaaatatact taaaaaaata aatgaaaaat atgaaacatt aaagaaaccc actgtggtag
    11641 taactgatgt cggtcaacat caaatgtggg ctgctaagta ctggaatttt aaaggtaata
    11701 aaagttttat aacatcagca gggttaggaa ctatgggatt tggtttaggt gcagctattg
    11761 gaactaaagt tggtaatgta gataaaaatg tggttttagt cactggtgat ggaagtttta
    11821 gaatgaactg taatgaacta gctacagttg caaattataa tgtacctatg cttattttac
    11881 tactcaataa tagaacatta ggaatggtaa ggcaatggca aaagttattt tccaatcaaa
    11941 gatactctca aactgacatt aatgaaaatg tggattatgt taaactcgta aatgcatata
    12001 atattgatgg atataaggta tccagtatag aagaattagg aaaggcgcta gatatgatag
    12061 attttaataa acctgtattt ttgcaatgtg atatagataa ggattatgat gtttatccta
    12121 ttgtagcacc taatgatgca ttggaaaatt tgatatgtaa ctaaaactta tactgaatat
    12181 tgataaaatt ttttattaaa tttttattgg tattcagttt ttgttgttta gagatagatt
    12241 ggcatttttt attttttcaa ataaatcaat gactatataa ttaagaactt attaaatttt
    12301 aattatacaa tttggaatag tattacaact taagtaaata ttaagtttta ttcgttagat
    12361 ttattattaa taccttatat tagttatggt tgttatatac tctaaagcct tgaaattaca
    12421 agtgtatagc tgactatata aatttgataa ttttagcttt taaaatagat aaattagatt
    12481 ttgccaccca tttgccaccg tattatattt ttgggtggca aactctaatt tgtaattttt
    12541 tcaaatatat ctacagtttc atttttcatt ttatcagtta catgtgaata ggtatccatt
    12601 gtagttgata gttggctatg acccaaacgg ttttgtatgt ctttaatgtt agcaccattt
    12661 tctaataata gagtagcatg tgcatgtctt aaagaatgaa aatggaagtc attgtttaaa
    12721 gctactcgaa tttgtcttac tatagtgtct aaagtgtgag tattcacttg ttgaccattt
    12781 tctttggtac atacccaatc actatcaaag taaaattctc catattttaa tttcattttc
    12841 ttttgatata atttatgttc ttttaatgcc tttattaaag tgtcacctgt aaatatagtt
    12901 ctgcaagaac tttctgtttt tggttgccct aattcaaaca ttccatttgg ttttttaatc
    12961 aaagtatgct ttactgtgat agttttatta tcaaggtcta tattatccca ttttagtgca
    13021 ataatttcac ctcttcgcat accagtatga aatccaatta gtaaaactat acgttgaaat
    13081 gaatcttgag gaaatatatt tagtatttga ttaaattctt ctaatgtaat agttttaact
    13141 ttattagttt ctgttttaga tttagttttt ggtatgctta catattgcat agggttttct
    13201 cgtatgtgtt tgtaaggatg gactgctgat tttaatgacc tatgtaatat ggcttttaat
    13261 acttgtaatg tattttgaga gtaatcatct ttgtactttt tatttatgaa gttttgtagt
    13321 attgcaggag ttaaagcttt tactttgtaa gctcctagtt ttggctttat atgtttttct
    13381 atgtttattc ggtagctttc ttgagtgttg tatttacagt taagtaagac atattctttg
    13441 taccaaaagt ctaagtagtc tgataaactg atattgcttt cttcaaatac tatgccagag
    13501 ttttcatatt catttagtgc ttctcttaag gctttttctg cttctttttt agtattgcct
    13561 ccaactcttt ctactttttt tctttttcct tctactatgc ctaggtcaaa gtagtaatac
    13621 catttgttac ttctttttct tactccacct ttcataatag tatccctccc ttttagaatg
    13681 tatgtttgtt tggtgtttat ataaaagagc agattaactg ctctttatat acttttgtta
    13741 tgtacaatat tatcttaatt ttgtttatct ggttttcact taatcatttt cttaatattc
    13801 ttacaatttt ttagctttta tgtgtagttt attataataa tattgaaata tatatttatt
    13861 aagtaaaaaa tctataaaag tagaataaat gagtttaaaa aatatcctca tatatgtaga
    13921 aatttggcaa attagttaat actaaaaatc tattatttcc taagtccaac atgcttttct
    13981 tttttgatag aaattctaat ctttttagta agaagttgat gctaacttgt aattcttcag
    14041 ctatttcgta tacacttgta gcgtgtgaat taataacatg tattatttct tcttctgtta
    14101 taagaaattc acatgcccat tttagtgctt tgttttcagt tttgtctatt aagattttat
    14161 ttttgtaact gttttttgaa gatacatagt ttccaacact ggtaaaatga tgtcctaatt
    14221 cttctgctaa gatttctatt agtttagcat tgttttgttt taatgaatta agtaatgata
    14281 taatctttag tccttgtctg tttatataca atccttttat gtcatctgct attttgtcag
    14341 tgtagtaaat ttctatctct tcattatttg ctaagtctaa aagtgcgtct agtttgttca
    14401 ttgaaatccc cctataaaaa gaatgtattt ttgatttttg ttatatataa agagcaggtg
    14461 tgaactgctc taaatattca ttttttatcc aaaaaagatt ggataatttt agctgtagac
    14521 aaaatatgga ttatagtata tgattataat ataattacat ataatatatg taagcactta
    14581 caaatgtgtg ttagtatagt tagcactaaa tttgtatttg tgcttaaagc gattaaagga
    14641 gttttggagc ggtgggtaga gttttactca ctataaccaa gactcttttg catattagag
    14701 tatttcatgt agtcatatat tctaataagc cttcttaaat ttgttttttc gcttgttttt
    14761 gcagactcta aaatattagg attttcctca aatattttct taagtagatt ttctaactgt
    14821 tcagtgtcaa tttctttttc ttctaaaaaa gcaataagtc ttgtagcttt ttcaaatgat
    14881 tgatgttcat cattccaaat accataaaca cttctatttt ttatgtaagt attatttcta
    14941 ttttttttaa tactattgct aataatattt tcaaagtcac tttctagtgc aattgtccta
    15001 taatctggaa attcaagtgt gctattaaaa agatgtttat ttaatggtaa tttattatat
    15061 tgcttaatta aagatggata agcatattca agtaattcat ctgatgaaaa ttctaagtca
    15121 ttcatgacta tatcacgata ccattcatca aaacttaatc cttttaatcc tttaagacca
    15181 aaatcacttg ccttgccaac tgctaaaact aaatcttcat cttttattct tgtatcatca
    15241 acactaccaa cccgaatttt agcagtaggt ttgttagtaa ttgtgaaatc gtaaaattct
    15301 tgtttgaaca ttcttaatat tctaactggt aattttgatt ttttttcaga taatgcctca
    15361 tagagtaaat taaaatcctc cagtttaatt ttagtcatag taatcatttt attatcaaaa
    15421 acaattgtat gacttgatat ttctatatca ttaaagtttt tttcatactc aatgaatatg
    15481 aaacgttcct cgagtttttt agcattttca ttagatagac aattaactat agcattaagt
    15541 atttttttta tatttacatc tgtaacagag taaccaataa atatgatagg aaactcaaca
    15601 aatatagtca ttagcttagc tgccaagtag gcacttttgc tgtcaaagtc tatataatca
    15661 gcttcattta ttacaatact atttggagaa gaaacacatc catgaatttt ataaatttct
    15721 gcaatacctt gtatagatga aaaaactaaa ttttcttgac ctatatatgt tgtataatta
    15781 tcaacgatag tttccaaaaa acaatcataa tttgttgtaa taaatcctga taaacttttt
    15841 ttagagatat tactaagttt ttcaacttca tcttgatatt tatctactat tttagaatta
    15901 tttttaatat acatagcaat ttctgcctta aatggagaaa ctcctgattt aacaatatct
    15961 aaatacttag agtctaagct tcgtatagaa gaatctgaaa accatttttt attaaaatca
    16021 ttttcaataa gttctgcaat tctaggattt atacccattt ttgggttctc tgattttgct
    16081 ttatttttat aacttgtata tataaagtca tcattactaa ttttttctgc aaagactttt
    16141 agtaaatcct cccaatttgg aagattatag tatcttctag ttaaaccaga accaacaaat
    16201 aaaaatggtg tagcattaaa tcggtttatg acatctgata ttatagattt catataattt
    16261 atcacctact tttaatttat tttttatact tatttattaa aaattcaata taatcattga
    16321 gttgttcttg agcttcctct ggtaaatctt tgtgaggatt aactctatgt gcagctacag
    16381 tgtctatatc attttttaca atagacctac ctaataaata atcagtagtc acattaaata
    16441 tttcagcaag gctagatagc atataagcat caggaactgt ctttccttgt tcataataac
    16501 cataagcgct tttggttaag tttaatttat ttgcaacatc ttcttgagtc atattttttt
    16561 cagctctaag ttcttttagt cttttttgaa ataatgtatt attacaagaa gttttgctag
    16621 aaatattgct tgctttatta tcatacctac ctattaaata atcaacagta gtgccaaaat
    16681 attcagctaa actagataac atttctgggg taggtgttct tttaccttgt tcataaaatc
    16741 catatgcact agtagttatg ttaagatagt tggcaatttc tttttgcatt acaccttttt
    16801 ctttcctaag aaatttcaat ctatctgata aaatgctcat ataatcactc ctcttaataa
    16861 agttgccttt attaaataat acaacaaata gttgtaaaat gaaataaaaa aataaaaaaa
    16921 ctatttacaa acaacatata gttgtgtatt atataagtat aaacaacaaa atgttggtaa
    16981 ggaggatata gcttgaacaa tctaaaggaa cttaggacag aaaggaattt aaagcaaaaa
    17041 gatgttgcat taaaagtagg tataactact agttattatg gaatgattga aagtggaaca
    17101 agagtaccaa gtttagcaat agcaataaaa ttatctaaat gttttggagt atcaatagaa
    17161 aaaatttttt taaatacaaa tacaacaaga tgttgtttaa aagagaggag ttaaatatga
    17221 aagatttaaa aatagtaaaa gttaataata aactaacaac tgacagtaga gatatagctc
    17281 taatggttga aaaagaacac aagattttac taagggatat aagaaattat ataaaccaaa
    17341 tggaagaagc caataaaaac atgagtacag atttgtaccc atctgattat tttattgaaa
    17401 atacttattt agatgattat aaaagagaga agccatgcta tgcaataaca aagataggtt
    17461 gtgacttcat agcaaataaa atgacaggca taaaaggtac ggcatttaca ggaatatata
    17521 caaaaaaatt tgaagaaatg gagcaagtat taaaaaatga acaacctaaa ctaccaacta
    17581 catataaaga agcattacaa catcttatag agcaagtaga agtaaatgag aaattacaac
    17641 tagaaggaaa aatgaaagac caagtaataa aagaactaaa accaaaggca gattatacag
    17701 atatgatact taaaaacaaa ggacttgtca caataactca aatagcaaaa gactatggaa
    17761 tgagtggaaa agaaatgaat aaaatacttc atgaaagagg gattcaatat aaacaaagtg
    17821 gacaatggct tttatataaa caacaccaag ggaagggata cactcattca gaaacaatag
    17881 acataactag aagtgatgga atgactgatg taaaaatgac aactaagtgg actcaaaagg
    17941 gaagattgtt tttatatgac ttattaaaag taaataacat attaccagat atagaaaaag
    18001 agtatagtta tcaaacttca atgttatgtt agtactttga aaaataaata cagaatattc
    18061 aaaaagaggt gatttaaagg ttgagtaata gaaagaagta taccttgagt attacgaaag
    18121 aattatacaa taaatgtaaa gaaaaagcta atcaaagagg tatgtcagtg aatgattaca
    18181 tactatcagt gattagcaag agtatataaa ttattcttca atattaattt taatttctcc
    18241 ttttctttgc tcataatctt caatatgttt ttttattatt tgttcaattt ccttattagc
    18301 agaacgacct tcgctttcag ctatatattt aattttttca agcagaactc tgtttattct
    18361 taaagtgtat ttaggtagtg aagttgacat aataatacct cctttttaaa gtctaaatga
    18421 tgtcataatt atatcataaa aataatttat agaaaatcta taaaatatat tgacggcata
    18481 aagacggcgt gatattatta aaacaagaaa ggggttgacg gcaaaatgaa ctcaaataaa
    18541 aagagaataa ctgttaggat gccagaaaaa ttaaatgaag aaataacgaa aaaatcaaaa
    18601 tacttagggt taactaagaa ctcatttata ttagatatac tatggaagga atttgagtta
    18661 ttagaatata gaagttataa aaaggaggta gataaacatg aataacttac aagtaataga
    18721 aagaaataat gagagagttc taactacaca acaattagca gatgtatatg aaactgactc
    18781 aagaaatata agtaacaatt tcaacaataa caaagataag tttattgaag gtaaacatta
    18841 ttttttattg caaggtgatg atttaaagaa ttttaaaggc attcatacag aatatgaaaa
    18901 cctaaaattt gcttcaaaaa tgtatctttg gactgaaaga ggagcaaata gacactgcaa
    18961 aatattagat acagataagg cttgggaaca gtttgataat ttagaggaaa catatttcaa
    19021 agttaagcaa cataagccaa cttgtataga agatgtatta atagaaagtt taaaagaaat
    19081 gaaagattta agacttcaag ttaatcaagc aaatagcatt gctttagaag caaagacaga
    19141 ggttgaaaca ataaaagatg tagtttcatt agactcaaat agttggagaa caaatacaca
    19201 tcaactaatt gcaagaatag caaaaaaaca aggtggtttt gaacatataa atatgcttag
    19261 aacagaaagt tatgaattat taaataagag atttggagtt gacctacata gaagattgat
    19321 caataaaaga agaaaaatgg cagaagaagg tgtatctgaa tctaaaagag agaaagttaa
    19381 caatttagat gtaatacaag atgataagaa actcatagaa gggtatgttg ctattgtaaa
    19441 agatatggct ttaaaatatg gaatatcaag tgatttaagc aaaaattaag ttaaatcaca
    19501 acagcacttt gaaaactaaa tataaaataa aaatatctcc cttaaaagtt ttttaaagag
    19561 agataaacac tttattttgt aactatttga atacatgatg gatgaatgca atagttttta
    19621 tctttgtaat ttatagaaac ataattacta gagtacattt tatcaaggtt ttcattaata
    19681 tattcaattg cattacagcc atttatagag ccaatatcag ttatatcaat ccagttatta
    19741 aatatcttaa cataaacaaa cttcatgata acaccaactt tcattagaat ttaagttaat
    19801 tataacatgg tgtactgaga taatgtgtta agaaatagat acagaatatt caaaagaggt
    19861 gattagatgg aaatagagca aacaacaata cgcctgctaa aaagcagacg aaagttgaat
    19921 attaatttct attttggtta ggcgaaagac ctaacaaaaa atctgtagat acattaagtt
    19981 tgttagaaat taatattaaa gtttctagat ttggttctct tgaaccagct tcataatact
    20041 gatatgcacg ttctgagata ccaaacaaac tagcaaattg cttttgagtc atattcattt
    20101 gctttcttac tagcttaata ttatctttga atttagtcat aactacacgc tccaataaaa
    20161 aaataaataa atttcttgac acgaacaata ttagcgtgta atatataaaa catagcacga
    20221 acaatattgg cgtgttaaat aaaaaggaga gggtgaaaat aaataataat ttaaaactac
    20281 aacgtgaaaa aattggctta acacaattag aggttgctca aaaagccaaa ataacagaga
    20341 gaagctatca atattatgaa gctggcgaac gtctcccaaa cattcgtaca gctttaaaga
    20401 tagctataat tttaaatact aattgtgaaa aactctttaa tgaataatag cataaaagga
    20461 ctcagattac aagaaaggag ctttagatat gaataatttg caacttaaca ataaaaatac
    20521 aataacaaca ttagaaattg ctgatatgtt agaaatcaga cactgggaag tcttaaggaa
    20581 attagaagga acagaaaaaa caaaaggaat tattgatatt cttaacgaca acaattttgt
    20641 tgtggttgat tactttataa aatcaacata tttggattca aaaaatgaaa gtagaccttg
    20701 ctataatgta acaaaattag gttgtgactt tctagcaaat aaatttactg gagaaaaagg
    20761 tattattttt acagctagat atgtaagaag atttaatgaa atggaacgag tattaaaaga
    20821 acaacaacct aaactaccaa ctacatataa agaagcattg caacagttat tagtagaagt
    20881 tgaagaaaaa gaacaattac aattagaaaa tcaagaaaaa gataaggtaa ttcagttaca
    20941 gcaaccaaaa gtactgtttg ctgatgcagt ttcagcttca aacaattcta tattagttgg
    21001 agaacttgca aaacttataa aacaaaatgg agtagatata ggacaaaaca gattatttac
    21061 ctggatgcga gaaaatggat atttaattaa gcgtaaaggt gaagattata atattccaac
    21121 acagaaaagt atgaatctaa gaataatgga agttaaaaaa agagtaatta ataatcctga
    21181 tggaagtact aaagtaacta gaacagtaaa aataactgga aaaggtcaag tttattttgt
    21241 taataagttt aaaagtagta aacaattatc aatgttaagt taaatcataa cagtaccttg
    21301 aaaactaaat acagaatatt ttggaaagga gagattgaat tggaaaataa gaaaatagaa
    21361 gaaatagaga aaagaataac catgcttgaa aatcaattgc aagcacagtt atttagtcag
    21421 ataacagctc aatcaaatag tgattttata gattatatgt accaatgtat agttttgtat
    21481 ttacatgaga tgaataaaag tgaaaaaaga aaaattagtg aaattactaa agaaagaatc
    21541 agaaaataag aatgataatt acaatataaa acctattctt ctagcaggtt ttgaagggtc
    21601 agttttcttt actgaagtta tcataaagtt tatctgtgat gtgtgttgaa gaatttcaga
    21661 ataaactcca tttactatgc cgtagtagtg aattagacaa gggttatgat aacctacttc
    21721 ttcaacaatc attaatacat cttttccaaa gttagtcaat tttagtgcaa tttcatgttc
    21781 atcatcaagt tctttttcaa attcctctat agatttaaga ataattttat attgaaattc
    21841 agcatagtaa aaatactctg tgttagaagt atcagagact gtctttctta tactttcttg
    21901 taattcttta gatatattgt ttgaaaactg cataatacac catccttttg aaaattttgg
    21961 aatttattcc atgtttatat tataccatgt agaactgagg tgaatacaat gttaataggc
    22021 gacaatataa agcaaatact aagaaaaaga gatataaaac cttataaatt agcaaaggaa
    22081 ttaaatatag atgtaagtgg tctatataaa ttgttgaaga ataaaaattc taatccaact
    22141 atagatactc taataaaatt agctgattat ttagatatta cattagacga attagttgga
    22201 agataaatat ttgaaaagag gggagagaat tttaacatgg atatttctga aagtataaca
    22261 aagcaattta gtgatagttt aaaaagttta atagaaatag agataaataa acaagaaaca
    22321 gatagagtta agagtcaaac tgttgaacaa aaggtaaaag tactggagcc taaagatata
    22381 gttgttttaa taaaaagagg ttatccaaat tatttgataa cagtagaaga agcaagggga
    22441 attttaaaat tagatacagt ttttatgcgt aggttagtga gcacaggttt gataaaatca
    22501 ctggctagag gtgatggtag aaaaatttca agatatgaag ttgatgattt tattgaaaga
    22561 aatcaaggta aaaatttgga tgaactttta aaagtagcag agagggggga tgaaattgtt
    22621 aagccttaat actaataaga ataatatagt aactcttaaa aaagatggaa aagctatagc
    22681 agacatagta tttaaagata ttaaaactgg taagaaaata tcggttggag tattaaataa
    22741 aaaagtgctg gtcaaataac caacacacaa aaaaataaaa aataaaatat aacacaaaca
    22801 aattatagca caaaaagaat ggatttagaa taggtaatat aacattctaa aaggtttaat
    22861 gtgtaataat tgtaacaatt tagaatgtag cttatataga tagtaataaa ttgggaggga
    22921 tttaaatgga agcagctaga ctaatagcaa taggtcaaat taaacaagca gaaaaagaaa
    22981 tatgtaaatt acaaggtaca aaaaataata gtagtttaat gtggtgggaa gccgtaaaat
    23041 ttgctagtca aaatatatta gagggtcttg aacatgacat tgagttagaa gcttctattg
    23101 agtttagaga agctatgatg tatcaagaag aacttgaaaa agatagacca atagatgtcc
    23161 agatataaaa aaagagcctt cgcacaggct ctaagtgaaa ataagttaca aaaattatag
    23221 gtatattata acataagggg gaataaatga aaacaaaaaa tgaaataatt aagggtttag
    23281 aagatagatt atttttatta agatttacaa cagtagatga agtagattgg gatgtaaaat
    23341 ttggacaaat atcagcatta gaattttgta tagataaaca tagaaaagga tgcactttgg
    23401 aacaattcaa agaacattta gacgaataca aattacaagg gaactatggt gattatatag
    23461 atggttttgt gtcagtttta gaaagaaata ttagagaaat ggagggagaa attgatggaa
    23521 gtgaataata tttacataaa attgatggat gtaagaatta agtttaacaa attagatata
    23581 aaaaagagtg gtcaaaacaa gtttgctaac tttaaatatt ttgagttagc agacttctta
    23641 cctcaagcaa cagagctgtt acaagaagct aaattatgcc ctatagtgac ctttacaaat
    23701 gattatgcaa ctctaacatt gattaatgga gagaaaccaa cagaagagat aatatttact
    23761 tctccaatga gagaattaca attaaaaggc tctaatgagt tacaagcatt aggaggaatt
    23821 gaaacatatc agacaaggta tttgtacatt cagttattaa acattacaga aaatgatact
    23881 tttgatgcta ctagtggaaa agaagattat aaaagaaatg acttaacaaa ctcctctatt
    23941 aaagcaagtg aaaatggtca aataaaaata agtcaaaatc aaataaaaag attgttttca
    24001 ataggaaata caataggcaa agattcagat agagtaaaaa gtgaagtgta ttataagttt
    24061 aataaagaag ttaaagattt aagtaaacag gaatatgacc agatatgtgt tggatatgag
    24121 aaattacaaa gggaaaaagg aataattaag taggtgaatt tcttgaagga cagagacaaa
    24181 gcaactatag agaaaggaaa tatacttagt gatgggtatg gtctttcacc acaattggta
    24241 gctagagatt catggctaac aacaggagca agagctttat atttctatct atccagtttt
    24301 gcaggagcaa gtgggacatg ttatccatct agggatatta tgactcatga acttggtata
    24361 aataaagata cttttagtaa atacctaaat gaactaaaga cgagtggtta tataaaagta
    24421 tataaaaata aaactaggga aggaaggatg caaaataata tatatgaggt agtatttgat
    24481 agaagctata tagaaagtca tatatccatt agatgtaaga aagaaaataa aaaaaaacca
    24541 tgtccgaaaa aagcagacat ggaaccatgt ccgaatttac cggacatggt tcaaccggac
    24601 atggaaaagt cggacactat aagtaacagt attataaata acagttttaa aagtagtatg
    24661 tatatagagc aagctgtgga taactcttta aaagaattta agaagctata tgaagaaaat
    24721 ataggagtag tatatccagt cacagctgaa tggttattag aagtatctaa tgaagtagat
    24781 ataagagtat ttaaaagagc tatagagata tgtgctgaaa gaatgaatat gaatttatca
    24841 tacttaaaag gaatccttaa aaagtggaag gatgcaaata taactacata tgaacagtta
    24901 gaatcatata aattacaaca tgaaaataaa aagtcaaaaa aaaccaatag tgtagtaagc
    24961 aaaaataagt ttgctaattt tgaacaaaca tttactcaat acagtaacaa agaattagat
    25021 gaaattataa agaaaagcca aaaggctaaa tttaaataat attgatggag gtattaaaat
    25081 gaatcaagtt gtattagttg gaagattaac tagagaccca gaactcaaat acataccagg
    25141 aacaggtaca gcagtagcat catttacaat agctgtagac agaaattata taaataaaga
    25201 aggaaaaagg gatactgatt ttataccaat agaagtaata ggtaaatcag ctgaatactg
    25261 tgcaaattac ataacaaaag ggaagctagt agcattagaa gggaatataa gagttgacaa
    25321 ttatcaaact caatcaggtg aaaaaagaat atttacaaaa gtcagtacaa aatcagtaca
    25381 atcattagaa agcaagaata aatcgagtaa ttcatataaa gagagtgtac aagatggaac
    25441 cataggacta gaccctcaag gatttgaaat tatagatgat gatgagttac cattttaatc
    25501 tgaaaaatta aatatgaggt gaaataaatg tttaaagtag aaaggtattt tagtggctca
    25561 gtagtggaca accttattga agatgacctt acatgtagaa actacttagc attatattgt
    25621 tgtttgttgg gaattacaaa aaatggaaaa aagatatatc ctaagccaga aaaaatgtta
    25681 gctgagtttg gagtaaagaa ggacagaaaa ataaaaaaag agttaccagt aagaattaga
    25741 aatgttaata caggggaagt aaaagaattt gagtctatag atggtgcagc ctgtttttta
    25801 agattaaaat atcaagcagt ttatcaagct attaaaaaga aaactaaaac aagaagtggc
    25861 tggaaagttg aatacattaa ggaggaataa tggaagtttc aaggacagaa tatacaatta
    25921 aaagagcaaa agagttatat gacaatggag aggatatatt tattgctata gataaggcta
    25981 gagaaaaata tgaggagatg attaaaagtg aatatcttag ctagtgtgat attagtaata
    26041 ggaagtttta tagctggtag agtttatgag tatagattga acctaaaagg gtgtgaaaat
    26101 tgtgataata agaaggtgca aatatgaatg tattaagtct attcgatgga attagttgtg
    26161 gtcaagttgc ttttgagaga gctagaataa aagtagaaaa ttattttgca agtgaaataa
    26221 aagagattgc gattaaagta gcaatgaata attacccaaa aacaatacaa cttggagatg
    26281 taagagagct aaatgtaagt aaaatcccta aagtagatat tcttattggc ggaagcccat
    26341 gccaaaattt aagtaaagga agattaatag ctaataaaat acaggatgga ttaactggag
    26401 ataaaagtaa tttgttttgg gaatatataa gaattctaaa acaattgaat ccagaatatt
    26461 ttcttttaga aaacgtagtg atgcccaaaa aagatgaaaa catgataagc caattgttag
    26521 gagttgaacc aatcaagata aatagcaatt tagttagtta tcaaaataga gacagattat
    26581 attggacaaa tattttaaat gttcaacaac ctaaagattt aaaaattagt tttcaagatt
    26641 ataaagatac tagttttgat tattgcaaag agtttgaaat taaaaaaact ccaagtagag
    26701 aaaaaatgtg gggtaatggt ttaaatggaa attgtaagaa tgtaacatat gaagacaaaa
    26761 taaactgcgt aacattaaaa caagatagat ttagtaattc aggtttagta gaatttgggt
    26821 ctttctgcag atacttaaca actagagaat tagagttagc gcagacgcta ccagttggat
    26881 atacaaaagg tttgagtata agacaagcac aaaatgtcat aggtgatggt tggacaatag
    26941 atgtgatagc acatatttta tcaaatatta actagttctt tatatataaa ttattattga
    27001 agcggttagc tatcatgata cttgtagcag taagttttat agctggtagg gtttatgagt
    27061 atagattgaa tct
//
LOCUS       DAGQVA010000052        25397 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.052, whole genome shotgun sequence.
ACCESSION   DAGQVA010000052 DAGQVA010000000
VERSION     DAGQVA010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.052"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(393..2312)
                     /gene="cooS"
                     /locus_tag="MIV85_002488"
     CDS             complement(393..2312)
                     /gene="cooS"
                     /locus_tag="MIV85_002488"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBY2961818.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(2919..3830)
                     /locus_tag="MIV85_002489"
     CDS             complement(2919..3830)
                     /locus_tag="MIV85_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBY2961819.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(3946..4524)
                     /locus_tag="MIV85_002490"
     CDS             complement(3946..4524)
                     /locus_tag="MIV85_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBY2961820.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRAIDEIPE"
     gene            4750..5673
                     /locus_tag="MIV85_002491"
     CDS             4750..5673
                     /locus_tag="MIV85_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2961821.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQGSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(5845..6987)
                     /locus_tag="MIV85_002492"
     CDS             complement(5845..6987)
                     /locus_tag="MIV85_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBY2961822.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(7005..8759)
                     /locus_tag="MIV85_002493"
     CDS             complement(7005..8759)
                     /locus_tag="MIV85_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBY2961823.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            8895..9101
                     /locus_tag="MIV85_002494"
     CDS             8895..9101
                     /locus_tag="MIV85_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961824.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(9106..10029)
                     /locus_tag="MIV85_002495"
     CDS             complement(9106..10029)
                     /locus_tag="MIV85_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961825.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(10283..11983)
                     /locus_tag="MIV85_002496"
     CDS             complement(10283..11983)
                     /locus_tag="MIV85_002496"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBY2961826.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(12393..12806)
                     /locus_tag="MIV85_002497"
     CDS             complement(12393..12806)
                     /locus_tag="MIV85_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBY2961827.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(12872..15250)
                     /locus_tag="MIV85_002498"
     CDS             complement(12872..15250)
                     /locus_tag="MIV85_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBY2961828.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            15569..17020
                     /locus_tag="MIV85_002499"
     CDS             15569..17020
                     /locus_tag="MIV85_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBY2961829.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(17224..19737)
                     /locus_tag="MIV85_002500"
     CDS             complement(17224..19737)
                     /locus_tag="MIV85_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBY2961830.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTSQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKALDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(19960..20781)
                     /locus_tag="MIV85_002501"
     CDS             complement(19960..20781)
                     /locus_tag="MIV85_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBY2961831.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(21299..21775)
                     /locus_tag="MIV85_002502"
     CDS             complement(21299..21775)
                     /locus_tag="MIV85_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBY2961832.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(21810..22388)
                     /locus_tag="MIV85_002503"
     CDS             complement(21810..22388)
                     /locus_tag="MIV85_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBY2961833.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGNEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(22492..25092)
                     /locus_tag="MIV85_002504"
     CDS             complement(22492..25092)
                     /locus_tag="MIV85_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBY2961834.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHSNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNVFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
BASE COUNT         7894 a         4605 c         2826 g        10072 t
ORIGIN      
        1 ccgtcttcag caaacatcct agagagcatt gaagaaaaag tcgttttacc tactccacct
       61 ttacctgtta ttgctatctt cataatccct accacctttt attactattt gctttttagt
      121 agttaatttt acagttaaat attttttata ctctatattt ttatacacta aaaataaact
      181 acagctagtc cttacaggaa ccaattaaat ttaccctact agcttttcaa agcagcatgt
      241 atagttttat tattctttaa tattgtttat attttattta ttcagtatat tcattatatt
      301 ttgatgttct ttactttaat atttgacttt attcaacttt attcaaccag aaacttctta
      361 taaaaacgtt tattctataa cttcactatt ttttaagctt cagccttttc tgccattttt
      421 tcttcaacta atgcttcaaa gtgaacacgt tttttctcta tatcttctat tattgtagct
      481 gctaactctt ttggatttgt atttacagta aatgtagctc caactttatc ttttaattca
      541 ctagttaata tatccactgc tcttgaagaa ccagctattg gaggcattat tcctaaataa
      601 gtgtctatac cagaagctac aacatagcat cctatagcaa ctgctttttc tgacatccac
      661 tctggagcta tacctacaac tggaaggtca cacatatcca tatctaagta attagctgct
      721 gctccaacta aatctagtat acggcttata tcaacacaag aacccatatg tagtactggt
      781 gggattccta ctaatttaca gacagttgca agacctttac ctgcatattt ttcagccgca
      841 tcagattcca ttaaaccaaa cttagctgct gctgaagctc cacaacctgt agtaactact
      901 attatgtcgt ttttgattaa ttctttcatt attgttacgt gagcctcatt tgaaactcct
      961 ttagcattgt tacatccaac tacaccagct gctcctctta atactccagc ttttaaacag
     1021 tctgttaatg gcttaactgt tcctgctggg tctatatgag agtttacaac tctgtctaat
     1081 tgatttacta ctgcttctac actataccca actgttgcgc ctgattttaa ttcaggtata
     1141 agtacttttg atttatctct atttttaaag tttaaaatag cttctttaac tattgcttta
     1201 gcatcatcaa gtgcttgttc ttctctaaat tcaatataag ttgaacctgt tatcttagct
     1261 tttggagaag ttgttacaaa tttagtatgg taacaatctg caactctagc taatgcaggg
     1321 aatatacatt gaacgtcaac tattacagct tcaactgctc cagttattat tgcaagttct
     1381 tgttgatgga agtctcctgc tatttttaca ccatgtctca ttgtaatctc attacctgta
     1441 caacacatac ctgctaagtt tattccatca gcaccaactt ctttagctaa agctactaag
     1501 tctggctctt ctgatgctaa aactatcatt tctgataatg ctggctcatg tccatgtaat
     1561 attatgttaa ctttattttc ttctaatact gctaaattcg cctctgttct tcttggcact
     1621 ggagttccaa ataagatatc gcttagacga gtacctatca tagaaccacc ccaaccatca
     1681 gccatagaag ttctaagact catgtgtatt aaactatcta tatcaccagt acatcctata
     1741 tgagtagagt gcattattgt tgcaatttct ctatctatag ctcttggctc tatagcgtat
     1801 tctttccata ttttttgtct tggttctggt gcatttttta taaatcttaa tgtcccaaaa
     1861 ggttttccaa attccattaa tgcaatttct gccacttcat gtgctacatc atagatatct
     1921 ctaccttctg tctctacatc ccattcttta gctaaagtaa ttaacttagc ttcgtctctt
     1981 attttatagt ttccatttgg atcagctaat gctaatgtat gtgctatatc tctagcatgg
     2041 tctgaatggg cagctgtccc accagcaacc attcttgcaa agtttctacc tactatagta
     2101 tgctcatctg ctccacataa cccccttgga gtcttagggc ttattctaca tggtcccatt
     2161 ccacatattc tacagcaaac accttgaaga ccaaaaccac attgtgcctt aaagccttct
     2221 tttctatcat acattgtttc tacgccttct tctctagctt tagctatcat cttctggctg
     2281 tttaaatcaa ttgttaacat tttttcatcc atattcctat cccctttttt tgatttttaa
     2341 aatcccccag gtgactgact tcatgtcata aaataataaa ataaatgctt tctaagttga
     2401 ttatatacta attttcagtg ctttgcttta gatttaaata tttttttaac aaaattagat
     2461 aatacataaa aattttattt tctacactta atttaagttg attttatcgc ttgtttttgg
     2521 ctatttgtta atatctaaac ctactttttt gatacttcag tttaattaaa ttatgttttg
     2581 atttttttaa atcaaatttg aaatttttct agtcattttt atattattgc agattgtttg
     2641 tgtatttatt atctttcact actgtttgga cttattacag atttttactc cctaaactta
     2701 attagtaaaa atttcttaga atagcatttt ttggactaat ttttttgaat ttttttattt
     2761 ttcctacttt aatattaatt atagcttcaa attgaacatt tgtatatatt catttgaagc
     2821 tataattatt ttttatataa aactttttta atacagcatt aatttagaca ttttgactat
     2881 tttttctact ttaattcatt tatttcaagc gatttatcct atttcatatt tttagctaca
     2941 atagccccat atgcaataga atataattta gattcatgtg aatcagctct tgacactaaa
     3001 actataggag cttttgcacc cataattata cctgctgatt tagagtctgc catatatgta
     3061 aaggctttcc ctattccatt accaacctct attgttggaa ccaatatgat atctacatct
     3121 ccagatactt cacttttaaa cccttttatc tcactagctt cttttgaaac agctaaatca
     3181 aaagccagag gaccttctac aattacattt tcaccaaatt ctccttcttt acaagctttt
     3241 gctaacatat ctgcatctac agttgcttgc atcttaggat ttactttctc tttagctgcc
     3301 aaacatgcaa cttttacagt ttccattcct aaagcttttg cagcttttat agaatttttt
     3361 aatatctttg ccttttgttc ataatcagga gctatattca tacctccatc tgtagttata
     3421 agtaatttat ggtatttttc taactcatat accataacat gacttaataa actatcagtt
     3481 ctaagaccat agtctttatt taacacttct tttaatatga cagatgtatc taataatcct
     3541 ttcattacaa agtcagcttc tttacttgat actaatttaa ctgctatttc tgcacactct
     3601 ttgatatcat ccttatccac tattttgata ccacttaaat caaatcctat ttcttttgat
     3661 atttctctta ttttgccttc atttccaacc aatataggag taattatatt tctttctaca
     3721 gcatccttta ttgccattaa aacttcttta tcatgagctg ctgctacaga gagtacaatt
     3781 ttctctcctc ccttaagttg ttctaaaata tcatctaatt tttttatcaa aagtaacccc
     3841 tcccttatat atatttaact aaataatacc atatttgcta taccttttct caatttattt
     3901 tttatgttat aaagaattta tataactaaa agacagttta atattttatt ctgggatttc
     3961 atcaatagct cttaaaagct ttgcaggaac accacctaca atagtatttt ctgcaacatt
     4021 ttttgttaca actgctccag cagcgataat tgcattatct ccaatagtaa ctcctggaac
     4081 tacagttaca ttagcaccaa tccatacatt ttttcctatt gtgattggag aaggataagt
     4141 tgtaccacgt ttctctggtg caataccatg gttaagtgta gccaatacca cattatgccc
     4201 aatttgcgta ttatctccaa tctcaatccc cccctggtct tgaaaatggc aactgctatt
     4261 tataaaaaca ttttttccta ttgtgatgtt ttttccacaa tctgtataaa atggtggaaa
     4321 cataaaaaat gattcatcta ccttttttcc aattaactca gaaaataaac tacggacttc
     4381 ttctggttca tgataagaag aatttaactt acttgtgatt ttcattgcct cattactcaa
     4441 cttaaccata aattcatgta tttctgattt actagaaaca ggttttcttt gattgatatg
     4501 tgttaaaaat tcattgatat tcattttata catcctttca atatgtgctt taatttattt
     4561 gtacattcta aataatattt taataaaaat taatttaatt tatttttatt aaaatatcat
     4621 tgcttctttt agtgtaatat acaattatat ctatatcaaa tatctatatt aaatacttaa
     4681 ctatacttaa aaagcatata aattgatata attatataat aaataagtta atattgagga
     4741 gggataatta tggaaataag agtattaaga tattttttag caattgcaag agaagaaagt
     4801 atatctggtg cggcaacctt tttacatata acacaaccaa cactttctag acaaattatg
     4861 gaacttgaag aagagttggg agttaaatta ttggttcgag gaaatagaaa aatcacctta
     4921 acaaatgaag gtaggctttt acataaaaga gcagaggaaa ttatatcatt agttgataag
     4981 gttgaattag aatttgacaa tcccaatgag attattagtg gtgatatata tataggaagt
     5041 ggtgaaactg aagctatgcg acttatagct agaactgccc atcattttca tcaaaaatac
     5101 cccaatgtaa gatatcacct ttttagtggg aatgctgatg atgtgactga aaaattagac
     5161 aagggactgc ttgattttgg tattttaatt gaacctgcaa atatacagaa gtatgattat
     5221 gcacaaattc ctgctactga tgtatggggt ttactaatgc gtaaagatag tgcccttgca
     5281 tcacaaagca caataaatcc aaaagattta tgcaatatac ctcttattat ttcaagacag
     5341 acacttgttg ataaagcaat ttctaaatgg cttcaaggca gtaatgaaaa actaaacatt
     5401 attgcaacat acaatttagt ttataacgct tctcttttgg tagaagaagg tctgggctac
     5461 gctctgtgtt tagatagact cgtcaatact acagaaaaca gtaatctttg ttttagacct
     5521 ctatctcctc ctttagaagc taaattaaat attatatgga aaaaacatca aatattttca
     5581 aaggcagcag aaaaattttt acttcaaata caaaaagatt tttcttctat catgttggat
     5641 acatctaagt tggatacacc taaagaaaaa taaatcataa taaaaagtga gagtgtctca
     5701 aaatgaactt tgcactgtat aaggcactct tttttataca aagtaaaata tatgttcatc
     5761 atttcagcac taaaaaagag gcttatctct attttgagat agccccactt aaccaataaa
     5821 attaaataca acttaacaat atccttactt atttattcca agttctctta gacaagcaat
     5881 cgtaatttca tcttgtggat ttaattcata agctctttct atatagtaag ttgcatcatc
     5941 aatatcacca ttatttaaat aagccattcc taaattgcaa agtatttctg ggtcttcctt
     6001 tatcttagcc gcttgttcaa aatactctat tgctttatct aaattattct tataagcctc
     6061 acaaagcccc aattccacta tagtatccac ctgattaggc tttattatca atatcttctc
     6121 aagatacatc ttagcctgct ctatttcgcc cataccctta tatccaagtg ctatcataaa
     6181 cagcaagttc caccaatcca tatgttcttc ttctaatgga agtaacttct ctaatccttc
     6241 cttaaactta ccttggaata caagtgtata tccttcttca tattgaactt taaagtccat
     6301 cttgcccaga ttctcttgta cctcagctac taaatcagca tctaacccta gccttaacgc
     6361 ttcttcccaa gtcagcttag tctttaaata ttgaccttga ttataataat ggtagcctaa
     6421 gtgataataa cctaatgcaa aattctcatc aacatcaatt accttttcaa gcttagccat
     6481 ggcttcaagt aagaatgcat tcattgcctt atcatccata tctttttgat actgtttagc
     6541 tatctcttgg caaacaatcg catagttata cattgcatct aaatcatctg gatacattgt
     6601 tataaatgct tttatatata ttaaagaatc tgtatgttca ccaatctcaa agtattttct
     6661 cgacatatat cccatatacg atttcaaatc caaatcaata tcttttgata aagcatttaa
     6721 aaacttctca tactctgcat tgtttttaaa cttactatct attccaatta tatatatcat
     6781 tgcatctgct atagacattg aatttaactt atcttgagca gtcttttctt ttatcccttt
     6841 tactaatacc tcatttttta taggtacatc taatccacct tttggcactt catagctttt
     6901 taatttaaac tctccaccat gttttatagt tataaaagct aattcttctg ctttttttag
     6961 caaatatttt tctatcttaa aatccatttt atcctcctaa atacttaaat ctctacttta
     7021 tgagttttag atttctcaaa tattttttta tcatcatact caaataagac tacattttct
     7081 acttctctta tttctgtatt tatatcattt tttaaatcca caacattaaa tctaaatggc
     7141 tcaaaatgaa catattttat tatatgttta gctggtttat caacaaaact aggtaaatat
     7201 gttgataagt tatcattatc ttgtaaaaat acatggcatc tattcttaaa atcatccaca
     7261 tctagcttat taaaaaactg tggtatattt gatgttttac ccagtgatat atagtcatat
     7321 tttaatatat cgttgaatac atcattatct atgttgattt tttcattata gaaatccatc
     7381 aatattttat ataactgatt ctttccttgt gccaaatcaa agtagccatt ttcatcaaaa
     7441 tacttggcaa aaacctcaaa gaatttaaaa gggctttttt tataaaatct gcctataata
     7501 tatctcatag ataacacaaa gtttttagaa ttgtagtatc tctccagtat atcttctata
     7561 tcctttagct tcaaagtttc ttcatagctt atataattat tgtataaaaa ctcatatgga
     7621 gcataatcct tatatttaaa accatgctca tctgcaactt ttctcatacc tgtcccttta
     7681 atcatcttta aaaagcctaa ttgcagatgc tctataccta gattaaatac atcattaaaa
     7741 gaattttcaa agctcttata atcttcataa ggcagtcctg caattaagtc taagtgttga
     7801 tgtatatttc tataagatgc tacagtttgt acaacatgag acaacttttt aaaatcatcc
     7861 cttctaccta ctgcatcaag tgttttttca ttcgttgact gaacccctat ttcaaattga
     7921 aaaagacctt ctttacaatc agccaaaaac tcaagcatct tatcatctat caaatacgct
     7981 gtaacttcaa aatgataagt tgtatatcca ttatcatttt tcataagaaa atccatgatt
     8041 tccatagcca cttttctatt tgcattgaat gtcctatcta taaactttat ttgtgatact
     8101 cttgcatcta ttaaagcttt taaatcactc tttatcctgt ctaaactaaa ataccttaga
     8161 cctggaatag tagatgataa acagtattgg cagttaaaag ggcaacctct tgatgattca
     8221 taatacacta ttctattttc atattctttt ggattcaagt tttcataagg actaggaatc
     8281 tcatccaaat cttgaagtaa ttccataggc ttattcacta ttatctcatt gccttgtcta
     8341 tatacaagtc catttacatc atttatttcc atctttcctt gcaagtgaag tactaaatct
     8401 ctaaaaatta attctccctc tccataaagt atataatcca caaaatcata ctttttcatt
     8461 gcctcataac tatcataact cacttccggt ccgcccaaag ctattttagt attaggtcta
     8521 atttttttta gattatcaca aagtttaact atatctccca cattccagat atatgttgag
     8581 aataatatta tatcatattc atttttatat atatccttta aaatatagtc caaatcgttg
     8641 tttatcgtgt attctttcat attaacttct atcaaatctc ttacaaattc ttttagatat
     8701 cttatagcca aatttgtatg aataaacttg gaatttaatg ttgttaataa aattttcaaa
     8761 tatttctcac ctctttttaa gattatactg tctttttgta ccccttatag gttaaaatag
     8821 tatatgtaaa gtctaaataa tatctatata attaatttat taatttcaag taatgtgagg
     8881 aaaggaagtt ttttatggaa ttaattgaaa aagtatctat caactcttta tcaaaaagag
     8941 atttactact tattataaag tctcttgaat acactaatga aaatactcaa attagtgatt
     9001 tcattgacct taggaataat atagtaaagg aattatgttt tttaactgac actaaggaaa
     9061 aagatttttt agattatcta gaaaaaaata gcacactcta ataacctaaa cctttttaaa
     9121 ctttaatata taaatacctg atttagaatt tatttttatg cttaatatat tatcattaaa
     9181 ggttttcgac ataactgtta tttgattaaa tatagggtct actatagtat taccttcttc
     9241 aagtcttata agacttcttg ggtctatgct tttattatat gccttaactc caattttata
     9301 ttttctcaat ttaacaacat attcggacat agaaaaaata aaatctatat tatcttcatt
     9361 taatttacta tcttcaccca aaatggataa tatagatttt tttatgctat taattccttc
     9421 attttctaca gttctatctt ccatatatac atcatataga acatttaaaa catttaataa
     9481 aatactttct tcatcataat cttcagattt caaatcaatg tacttatcaa ttaattgtat
     9541 tgctttaatc cttgccatct gaaactttac aacatctgat ttgtctaatt ctatagaaaa
     9601 tcctattatc ttgtctttaa tactctgtag taattcgaca tactctattt tactattatt
     9661 tataagattg tgcataatgg aattatacac cacagaacct aataaataat caaataaaag
     9721 ttcttctttt ttaaaataaa taacatactt ttttattagt ttaataacct catcttcact
     9781 tttttgaata ttagtatttg ataaaattag tggtaataaa atatttaaaa aattgatatt
     9841 tcctattttt tctccataaa atctatagta aataagttca tctctcagtc tattttcgtc
     9901 tatatacaca catctttgcg ttttatcatc tattaaggat tttgtattta ttatagttaa
     9961 atctttaaga gccctacttg cactactaaa agaagatgtg tagacttttt ttagtaattc
    10021 gtcattcata aatatatcct ttctgaaaaa ttgaatgtaa ataaattgtt attaaaaaaa
    10081 aagagacagc ccgtttaaga agctgtcata tataggggga tagtagtgta caaaaatcat
    10141 tgtaatctac tatctatata ttattatacg atactacttt tttatatgta aagcatcagt
    10201 tttcgacatc cctatatttt acagttatac aaattgcgta ctaagttcaa ttttattctt
    10261 tttatttcaa cattttatca tgctacattc tttcaggagc gtgcattccc aacaatttca
    10321 gagaattttc taaagtttgt tttgttgcta aaactaatgc aagtcttgct tttcttattt
    10381 ccaaattttc tactaaaatt ggattgtcat gataaaattt attaaacgct tgagctaaat
    10441 ctagcataaa tctagtcact atatgtggct catttttctt tagagcaagt aaaatattct
    10501 tattgaatga ttctataact ctaagaactt ctgcactatc ttcatcagct aatagactat
    10561 aatctatatc agaagtcact tctacttctg cttttcttaa aactgcacag catctagcat
    10621 gtgtatactg aacatatggt ccagtctcac catcaaaact aagcgttctt tcccaagaga
    10681 aggtatagtc tttaattcta ctattagata actcttggaa tactactgcc ccaacaccta
    10741 cttgcttaga tatttcatcc acatttttag catttgggtt tttagctagt ataatttcct
    10801 tagttttatc tatagcttga tttaaagcat cttctaaaaa tactactctt ccttttctag
    10861 tcgacatagt accttcttca agtgcaacca taccaaatcc aacatgaatt aaatcttttg
    10921 cccaatcata tcccataagc tcaattacct taaaccattg ttggaaatgt aagttttgtt
    10981 gagaaccaac tacatatata cacttgtcaa aatcataagt ttcttttcta tatattgcag
    11041 cagctaaatc tcttgtcata tataacgttg aaccatcatt cttagtaata agtgctggtg
    11101 gcattttata ctcttctaaa tcaacaattc ttgctccttt agactctttt aaaagatttt
    11161 tctcttctaa tagttcgata actctgttca ttttatcaga ataaaaactc tctcctgcta
    11221 aagaatcaaa ttctatatct aaaagtttat aaactctgtt aaactctttt aaactctcat
    11281 ttctaaacca ttgccataat tcttgtgctt cttcgtcacc attttctaat ttattaaacc
    11341 atgctcttgc ttcatcttcc atttctgggt gttgttcagc ttcatcatgg aatcttacgt
    11401 ataattttag taattctgga attggattag actctactac ttctttttct ccccactttt
    11461 taaaggccac tattaactta ccaaactgag ttccatagtc acctaaatga tttattctta
    11521 tagtcttgta tccttgcgaa tcatatatct tatataaagc attacctata actgtagttc
    11581 ttatgtgccc tatatggaaa ggttttgcta tatttggaga agaatattca actattacag
    11641 ttttatcttt tccaaaatca ctatgtccgt aattttcttt ttcatctaaa acttttttaa
    11701 ttacagtttc tgctaattga gatttattta caaagaaatt tacatatccg cctaattgta
    11761 ttacttttgt tatctctcca cttggttcta tactttccgc caattcactt gctatcatgt
    11821 ttggagcttt tctaaacact ttggctaatt taaagcatgg aaaagcatag tcccccatat
    11881 ccttatttgg tggaacttct ataagtgcct ctatctcttc tttcgataaa tcttctattt
    11941 tttctttaag gcaatttgat attgccacct taaaatcttg cattctgttg ctcctctcta
    12001 cattgttcct ggtttatatt gtgcttatct ctttatgtta aatcaaattt cgtgtttttt
    12061 caagtatttc attacagtgt aaaacacttt agtaattatg ttttctgtat atattaaaaa
    12121 tactataatt tcagttttta atcacactat tattgatttt ttataagact tttttctatt
    12181 ttattgtttc ttgtactatc cagttgactt tatatacttt ttttaatctt ttatctgttt
    12241 tcatacatca atgtcagctt tatatacatt tttttaatct tttatctatt ttcatacatc
    12301 aatgtcagct ttatatactt tttttacttt tttatctatt tttatacatc aatattagct
    12361 ttatatactt tttttactct tttatctatt ttctataaat ctttttcact cttaactttt
    12421 attccttctt cttctaatag ccttgctgtt atacctttcc ctggtatctt tttacctgaa
    12481 aaactaccat catatattag attacatcca caagaggggc taccctcttt tagtattgct
    12541 tcgctacata catataaatt tgctattttt agagtttcat tagcccctct tacaaagttt
    12601 tctgttacat ccttattatc tttagtaatt acttttccat caactatctc agcaggtggt
    12661 cttggtgtag atagaccacc taactgctct gggcatacaa gtgtaaattc tttgcctttt
    12721 aaatattcct tgactttttc attatcatta ttatcgccac tatatttaca atttattcct
    12781 attaaacatg cagataccaa tatcataaaa atgtgctcct atacaaatta tatatattct
    12841 catacaaatt actaatgtat tcttatacaa attattttaa tttaacaatt gttactcctg
    12901 ctccaccttc tccatattga ccacctcttt gtgattttac atgtctattt cttcttaaaa
    12961 tgtcttgtag ccctgctttt aatactcctg tacctattcc atgtattact gttacagact
    13021 ctaaacctgc cacatatgca tcatcaagat acttttctac ttccattata gcttcttcta
    13081 ggtttaaccc tctaaggtca acttcatttt ttacactacc agattttgac cttataatgt
    13141 ttctcgttga tttagttaca tttgttgaaa catctttgcg tgttttttgt aaagatttaa
    13201 aaggtagagt catcttcatt ataccaattt gcactactgc ttcttttctc tttttatcta
    13261 ctgaaactac actaccattt tgatttaaag ttattacctt aacttcttca cctggcttta
    13321 agtcttttat ctccttattt gatacctttg gaactatcat actttttact gttggctgaa
    13381 gacttcccat agagctagtc aattcttttc taagttcttc tatcttacga ttcttttctt
    13441 ttgaagctct ttcttgttca agacttctaa gttcttttat tataatatct acttcttctt
    13501 tagcttgtct tataattgaa aatgcttctg atttagcttt ttcaatcatc ttatctcttt
    13561 gactgaccaa tttttcaagt ttttcgtcat actctacttt cagtttttca atctcttctt
    13621 ttaatctttc agcttcttct ctatcttcta ctgctttgat tctattcttt tcaacattct
    13681 gtaacacatc ttctaaagct atgttttctg tatttatata ttctttagca cgtgaaatca
    13741 cataatcact tagcccaagt tttctagaaa tctcaaacgc atttgatttt ccgggaacac
    13801 ctataagtaa cttatatgtt gggcttaaag tttctatatc aaattcaact gctgcgtttt
    13861 ctacacctgg tttagtaaga gcataatttt taagctcact atagtgagtg gtagctatac
    13921 atttagctcc tacagaattt atatcttcta atactgctat tgcaagggca gctccttcaa
    13981 cagggtctgt tcctgctcct aactcgtcaa atataactaa agagtctgct gttacgtttt
    14041 gtaatataga tactatattc gtcatatgag atgaaaatgt tgatagactc tgttcaatac
    14101 tctgctcatc tcctatatct gcaaatacat tatcatatac acacatacta cttccataat
    14161 cagcaggtat atgaagtcca ctttgtgtca taagtgcaaa tagacctaca gtttttattg
    14221 taacagtctt accacctgtg tttggacctg ttatcaccaa tgtatggaag tctcttccta
    14281 aataaatggt atttgctact accttctttt tatccagcag tggatgtctt ccatttttta
    14341 tgtttaaata tttatcctca tttaaagttg gttctattcc tctcatctgt atagaaagtt
    14401 ttccctttga aaatgcaaag tccaatcttc caagtatctc ttgattagag attaaatctt
    14461 cgctcacttc tccaaccata gcagaaagct ctgataaaat tctttctatt tcttcttgct
    14521 cacctagttt taactgtctc aattcattgt tcatctctac tatagtcatt ggctctataa
    14581 aaagtgtcgc accagaagat gactggtcat gcactatacc agctacttgc gacctatatt
    14641 cagattttac aggtactaca aatctatcac ctcttagaga aattattgca tcttgtaagt
    14701 acttttgata agtagttgaa cttattattg aatttaattt tgacctaatg gattgatttt
    14761 tttgggctat tcttcttctg atatctctaa gtgtacttga agcattgtca gatatttcta
    14821 cttcactaat tatagcattg tatatctggt cttctatgtc cttgtataca tatagagaat
    14881 ttgatagaga ttgtattatt ggataattaa aatcttcttc atcactacta gataagctat
    14941 ttcttaatct tctagccact cttaaggtat ctgctatcat aatcagactt cctgggtcaa
    15001 gagaagcacc tatataagct ctctttacct tatcttctat atcatgaata ccttccaacc
    15061 ctactgaacc tctctttata ataattgatt gagcttcact agtttcttct agcatagatt
    15121 tcacttctac aaaatcagta tttggtacta aattttctat atattttaga cctaaagaag
    15181 atgaggcttt cttctttaac aaatctatta ttttattgta ttctagaact cttaacgatt
    15241 tctcattcat tttctatatt caccatcctc gatattttaa cttttttatt taattttaaa
    15301 aatgtatgtt ttcaagcatt tccaataaaa actgcaagtt ttatttcttt ttcatttcta
    15361 aaattattat attttttctc ttttagatat attttacaca tattttgtat tatactatgt
    15421 atgtagctat ctatatatta tacataaaca tgctttattt gtaatataat ctgttaaaaa
    15481 atcttcttta atatttttaa aggagtttat tttagcttat aaaaaaaaat agctacttat
    15541 atagataaat taaggaggaa catgagtcat gggaaacgta ttagaaggat taaaaccaga
    15601 aagtgttttt aaaaactttg agaaaatatc tcaaattcct agaggttctg gaaatgaaaa
    15661 aggcataagt gattttttac ttagctttgg taaaaattta ggtcttgaaa ctattcagga
    15721 tgaaagctta aacataataa taagaaagcc tgctacaaaa ggatatgaaa attgtccagg
    15781 tgtagttctt caaggacata tggatatggt ttgcgaaaaa gaaaagaatg ttgaacatga
    15841 ttttcttaaa gaccctataa aattaagaat tgatggtgac atgatatatg ctactggaac
    15901 tactctagga gctgacaatg gtatagctgt tgctatgggt atggctatat tagaagataa
    15961 tactttagag catcctgcac tagaagtttt agttactgtt aatgaagaag atggtatgaa
    16021 tggtgcagat gcactagacc ctagcttaat taaaggtcaa tatatcctaa atatggactc
    16081 cgaggaggaa ggatacttat tagttagctg tgctggtggt aaaacttgtg ttgttagttt
    16141 acctgttgaa tacaaggaag ttaaaggtga caaacaagga ttattagttg aggttactgg
    16201 actattaggt ggacactctg gtatggaaat tgttttacaa agagcaaatg ctaacaaagc
    16261 aatagctaga gtattaagtg tattgaatgt tgattatgaa ttagcttctg ttgatggtgg
    16321 tactaagcac aatgctatac ctcgtgaagc taaatgtgta atagctgtta ataaagctga
    16381 tgttgaatct gctaaaaaac aaataaatga cattttaact gcatttaaac atgagtttac
    16441 tacttctgac cctggcatga cttactcagt agctgaaact tctgtagaca aagttcttac
    16501 taaagattgt aaagaaaaag ttgttcaaat gtcttgctta actcctcatg gagttcaatc
    16561 agtaagtctt gatatagaag gattagttga aagttctact aacttcgcta taatcgaaac
    16621 taaagaatct actattgaat ttttaacttc tgttagaagt tctgttatgt ctattagaga
    16681 tgaaatcgct gatagaataa gacttttggc tcaagcttta ggtgctaatt acgaccttat
    16741 agctcaatac ccagcttggg aatttaaaaa aggctcaaaa ttagaaaaaa tatgcagtga
    16801 aacttatgag aaattaactg gtaaagttcc tactgttatg gctctacatg ctggtcttga
    16861 gtgtggatta ttacttgata aacttcctca tgctgaagct atctctatag gaccagatat
    16921 gtttgatgtt catactccaa atgaacatgt tagtatccct tctgtagcta atgtttggga
    16981 ttatgttatt gaaatattaa aatctatgaa ccaatattaa atttaagttt tgattctaag
    17041 tagattttaa ttttaagtaa tctatataaa attaactctg taaattaata ctacggttag
    17101 tataatattt actttcaata ttaacttata gaaataaagc ctaatgatag ataataacat
    17161 gtatcattag gctttattgt aatttaaata ttattaagct ttattctgtt ttaaaattaa
    17221 ttcttatact attttaaatc tatttcttcc ttgtctctta gaatcataaa gagcattatc
    17281 tgctatttga tacagttcat catactcttg accaggcttt gctataacta cccccatact
    17341 aatagataaa ctttctccat ttggcaactt aatgagatga atatgattgt atacatcatt
    17401 acatttatta ataagttctt ccttatttat tatatcattg atataaacac taaattcatc
    17461 tccacccaaa cgacctacta tatcattttt tgcaaaactt tcatcaagtg cctttgcaac
    17521 atcaataagt actttatctc ctaacaagtg accataagta tcattaatcg atttaaaata
    17581 atcaatatct ataatcaata aagcaccatt tttttcagtt gataaattca acaaattttg
    17641 tgaagttaat tttctaatat atgctgcatt ataaatattg gttaaactat ccctttgagc
    17701 cttatctaac aatctattct tttcctcttt ttcagaatca atattacata ttttcccgat
    17761 tacatacatt ggtatttttc tatcattata aattattttt gaagtaactc taatccaatg
    17821 aaaagtatca tcaagcataa tagaatacat ttcagttgtt ccattttctt gtgattttat
    17881 tacatcaaaa aactttttat tatattcttt ccttatttta tctctttcat tttctatatt
    17941 gccattttca ctttccttat catttttatc caaaccataa taagtctcaa tacccttttc
    18001 tggcatagaa attatcaatt tatcttgctt ataatcatac tcaaaaaagt attcacttgt
    18061 catttcatac aactgagtat gttttttgag ttctaaagat atcttctcgt tcatacttgt
    18121 acgagtatgt aaaccaaatg ccataaatcc aataatacaa attaataaac tggctacaat
    18181 aaaaatagtc tcaattggat tctgttgcat aatataaagc aacgagaaat cttgtctata
    18241 tgtagtattt tggtagacaa ttgattgcat tttttctgat gaaatactta taatagcttt
    18301 attaaatata ttcaataatt cttgtttatc ttttttaatt ataccaaaac aaatactctt
    18361 tgctttatag gtttgaggaa ctagacgcac atttttatac ttaggttgat tcatatagta
    18421 ctgcatagaa taaccttcgc cataagtgta atctgcatag cctttattaa cagcttctat
    18481 acactcttct aaattatcat accaaactat attctcttca aactgaccat aataattaat
    18541 acctttggct agagctacac gttttccatc taaactattc tcatttaatt tattattaat
    18601 catcatagta tattgagtag aaagaaaagg ccgagacata gctatattat gttcacgaga
    18661 gtattcataa tcataaatca ttcctgctac aatatcaatt tcacgctttt tagtcatgtt
    18721 ttctaaatct tcttgagatt ttacaggcac aagttcaaat tctaagcctg ttttatcaca
    18781 tatatgattt aacaaatcaa ttgatatacc tcttaattca cctgtatctt tatctatatt
    18841 ttgaaatggt ggtttgttta aaagtactcc tacttttaat ttttctgtct ctttaatgta
    18901 attagtttct tcatcagata aaaacatttg attattctct ggtgtaaagt atttttcata
    18961 taaagtagtt gaaaaatatg ggtctttctg ttcaatatta ttaattgctg agttaagctt
    19021 ttgagttaaa tttgtactac ctttaggagt aatgaaataa aatggttttg atgaaaattt
    19081 tgctacagta cgtacacctt ctattgggtt catactcaca ttaagaagta catctgcttt
    19141 accactcttt agtgcttcta gttgctcatc atttgtttta caatatacca attcaggtga
    19201 cataagattc attttacaat actcatctaa ttctttaagt ctagtatcag aattttctat
    19261 tacagcaata cggatttttt tcacatcttg tgaactcatt atgttatcaa tatctgtatt
    19321 ttcatataat gcttgtagta ctgtatttgc tactccataa ttattccctg cataattata
    19381 tattttttgc attggttcat tgtataacat acctcccatt atatcaattt caccattttc
    19441 taacatcttc attaattttg taatagattc atttatctct ccaggaactt gaacaaattc
    19501 ataattccat ccagtatact gtgcaatttc tagtaaatat tcatatgtat acccaaaata
    19561 gttaccttgc tcatctattt cagttaaacc tttttgaata ggataagcaa cacgaatggt
    19621 acgattatca ttacctatag cgttgatacc aaaagaaaat atgcaagaag tgaatataga
    19681 tgtaattaca ataattaata aaagtaattt ttttaaattc actacacaat cctccatata
    19741 gttaagattt acagtataaa ttactgcata aacttgtaga catgtaaaaa tagattagta
    19801 tataaaagga tatataaatc tacttagaaa tttaaatatc cttaatatat acaatatatt
    19861 taaattataa ctcatttata tgtctattac aacaaattta ccctgctaaa tacctactct
    19921 atatcccata attttacaag ttgtagtgaa gtttaagttc tatctcacct caaatttagc
    19981 agtgtttcta tttacagttc ttttatattt cacatctgga taacccaata taaatgaagt
    20041 gataactgct tcgttctcgc tcattcctaa cagttctttt atctttggct ctacatttga
    20101 tgccataaca aaaaatccat tataacaaat tcctaatcct tgagaatagg ccataagttc
    20161 catattagat gcagccaatc ctccatctac ataagcactt ccacctagag acatatcacc
    20221 tacaactacc ataagtagtg gggcatcata aaataaagaa tcatttccgt tctctttgta
    20281 tcttttgtac attttcttaa atgtattttt atagatagaa cgtacagggt cattgtcatc
    20341 agtatctaat gccaaattat aaagaccttg tattgccagt tctttcactt cttttagctt
    20401 ttcttttact aatatgtatc ttataggctg tctattacca cctgttggtg tgtatctacc
    20461 agcttccact atgtttttta ttttttcttc ttctacctct atatctttat attgtcttat
    20521 acttcttcta aatttaataa aattcaataa cttttcgggt tctaattcaa aactttcacg
    20581 attgtattct attacttcat ttttatcaaa tccttgcatt tctattgcat ctgttgggca
    20641 aattgccata cagtgaccac agttaataca gagaatattt ttaacctttg ctttatcatc
    20701 cttaactttt attgcattta caagacagtc tgattcacac atcccacagc ctacacattt
    20761 ttctaaattt atgtctatca ttccaaatta ttcctccttt taaaaaattt actttagtat
    20821 aaaacaaata gttgtctaag tcaattttta tttttttaac aatatactag ccttaactac
    20881 actttaatgg agaaaaatat acataaattg gaacttaaat tagaacttat tcaaagtaaa
    20941 agataaaaga agtagatgtc taaaagtgaa ctttttagtt aattagatat tctttattgt
    21001 atgaaatcaa gtggatattt atcatttcaa caataaaaaa ggcttacctc tattttggat
    21061 atgtccctgt caagtagaca gactaaaaaa aggctatctt tatgcactga gatagcccct
    21121 tttcccaact actattgttt atcttaatat tagtcaataa atttaatttg ctataacctg
    21181 taagttacat tttaatttga tgtaacttta aattacattt ttaagtaata tctttaaatt
    21241 atattcttaa aatatatcat taaactacat tttaattaat ctaaaaacta tatcttaatt
    21301 aatctaagaa acttacatta taatctttta gtttcccatt atcatataca atctttgcac
    21361 taaagatatt tccagtctta gcccaattta agaacagcct gtcaccttcc cacatattta
    21421 aatcgaatat tttatcatta tcaacccaaa ttaaatttcc ttctttacaa tcatttaaat
    21481 ctttttcaga taattcacct tcaaactcat ctgagaaata caaaaacata taccaatctt
    21541 cttcatcttt aaattttgga aaagttatca accctttata tgacaatgat ttaagagtaa
    21601 gaccagtctc ttcttttact tctctaatta cacattcttc tggagtctct ccttgctcaa
    21661 actttcctcc aactcctaca tacttacctt catgtatatc atctttcttt ttatttctgt
    21721 acaacatcaa agtcttgtca tctttttcta tataacaaat agttgtaagt ttcatgtatc
    21781 tcgccttgct ttctctttta tattctcaac taattatttt cagcactttc aagcacatca
    21841 cttatattct tcattgcatt aagagaaagc tctgcaaatt catcaaatgg aatccctata
    21901 tcttctatac ttctcattgc atctctattt acatttgaag caaatctcgt ttctttcatt
    21961 cttttaataa cagacttagt ctttacactg gtaagttttt tatctggata aactaaagct
    22021 atagcagtta taaacccagt tatagggtct gctgcatata ttgctttttc cattaggcta
    22081 gttcttgtaa ctcccattcc atcatgatga ccaagtattg ctctatacat ttcttcgtta
    22141 ccgaagtttt cttttttaag cagttctact gttgttgtag catgtccttc acatatttct
    22201 cctggctttc ttccaactat atctgaatcc aaatcatgta aaagacctgc cactgcccac
    22261 tcttcttctt tttctggctc tagtcttttg gctaattctc tcataacagc ttcaacagca
    22321 taacaatgtt ttctcattct atcagtttct aaatacttaa ataaaatttc taaagcttct
    22381 tctctcattt tcaccaatcc ccctgttttt tcacatatat gatattttta tatattaata
    22441 cacataaatt caagctttta tatatattca tgtatatttt tcatgttata tctattctac
    22501 acctttatag tagtgtcctg caactgttcc aatttcatct aatttcttat acaagtctgt
    22561 agcctttttt ccaagtttat aattattact cagtacctca atgtgagctt caataacctt
    22621 tttaaccatc tcactatctt caactgtaaa atctatccta aatacatcta ttccaatttc
    22681 ctctaactca tatagattgt ccaacataca agtaaccttc gaattgtaaa ttgtacttct
    22741 acagaatata tcttgtgtta tcctataact tgcatccgta aagtctctta aagcataact
    22801 actttcctta catttagcaa ctctcttgtc ctttttacaa tctctaacaa ctactcccat
    22861 aggacagtat tctgtaacca tcataggagc atatccatat attactgctt caatttctac
    22921 atctgtatat tttaaagttt gtttaatttc atttaagttt agttcttgtg acaaacaaac
    22981 tgtacttgct ccctcttctt tgaagtgatt tatactttca ctattgaata catttaagta
    23041 gcaatctata tttaagtctt ttttcttaaa gtattccata gagccccagt taccaatttg
    23101 aaccttatta attcctttta tattatccaa tatctcaaat tgcttgtact ctttatttct
    23161 aacaatcctt ggtgctgaat agattaattt tttgtcagtg actgctgtat tagagtggtt
    23221 cttattcaaa gtatctattt tacttgtatt tgacaaagta tctatgttat ttgtatttga
    23281 acccattagt tctttaggag tacctaaaga cgaagaagta tctaaatcca tagaaatact
    23341 tgaatctata gaaatatttg aatctataga gatacttgag accatttgta aagcttttga
    23401 taatgtattt atatcttcat aatagattaa atctacatta taatttaata ctgcttctaa
    23461 ttgctccaag ttcttaactt taactctaat cttaggagct gtatcaagtt ttttctgttt
    23521 atttactcta tttggctggt attttaatct attcttctta aattttctat cttttatctt
    23581 tattctttct tcatctaaaa gctcaataca atcccttctc atttgattta acacacttat
    23641 aggcatactt acaccttcat ccaggtcaat ttctatctct tttaacttat atggtgtatt
    23701 tccaagcttt tgaatttgtg tttctatttt ttctttactt aaagccacct ttatagcttt
    23761 ttcaactatt ttgtctcctt ctaccaccga tttatttcca caaaaatcac ttataaaaag
    23821 ctctggcttt ttacctagtt taatactcac ttttgcacgt atattagttt ttatgaactc
    23881 tttatcttgc tgaaatgtag cttgtactct atccattaat tcgctgtcag aagtcttata
    23941 tataagctga tttctctttg cttctccaac aaaatctaat tctatcaaat cccctttatg
    24001 tgctattgta gttatctctc catcctttat tattcttcca atagtacctc cacctaagtt
    24061 aattccatca cctttcttaa gcgtattttc tagcattact ctaagtcttt tgttctttct
    24121 attataatct aaaacttttc caatatatag cccttgatta ttaggtctat tagagttcat
    24181 tatatcctta ccaacttcac ctaatatata tccttttgta aactttctat taaatatggt
    24241 atacaaatta tttattattt cctcagaaat acttattttt ttcttatcta caaattcatt
    24301 aatcgcttct ctatatcctg aaaccacagt agctacatac tctggctttt tcattctacc
    24361 ttcaattttt aaagataata cacctgcttc aattatttta tccaaatctt ctatagtact
    24421 taaatctcta ggactcaaca aataatctcc attacttttt actacttctc ctgtatttat
    24481 atctatcaac tcatactttt gtctacatgg ctgtgcacac ctacctctat ttccagacct
    24541 attgcctatc atactactca taaggcattg acccgagtaa catacacata aagctccatg
    24601 tacaaaaact tctatatcta cagttgtatt ttcacaaatc cattttatct catcaacatt
    24661 taattctctt gctaaaacaa ctctatcaaa ccctacactc tgaaggtatt ttacatcttc
    24721 taaggaatgt gctaccattt gagtgcttgc atgtagttca aagtcaggta atagtttttt
    24781 tataagtctt gccattccta tatcctgtac tattaaagca tcaatatcta tatcgtataa
    24841 aaattttaca tactctacaa aatcttctat ttcatactgt tttatcaatg tatttacagt
    24901 aacaaagact tgcactcccc ttatatgaga gtatttaaca gcctcaatca gctcatttct
    24961 atcaaagtta tttgcagatg ctctagcact aaagtcttta ccacctaaat acacagcatt
    25021 tgctccgttt tgaactgctg cttttaatga atcaaaagag cctactggtg caagtaattc
    25081 tatttttttc atatttttct cctctattta tacttgttag gttaatataa ttatatctat
    25141 aacttaaata tttgtattaa atttatatat ttcttactat attttaaatt cttcaatcaa
    25201 tttatatatt agttatttat atttggttca tttgagttaa catatacatt atttactata
    25261 tttagtatat ttctattaac ttatatattg attactgtat tttaaattct tcaattaatt
    25321 tatatactgc ttactaaatt taaaacattt taattaattt gtacactgtt tactatactt
    25381 gaaatacttc tattaat
//
LOCUS       DAGQVA010000053        25289 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.053, whole genome shotgun sequence.
ACCESSION   DAGQVA010000053 DAGQVA010000000
VERSION     DAGQVA010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.053"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(41..364)
                     /locus_tag="MIV85_002505"
     CDS             complement(41..364)
                     /locus_tag="MIV85_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBY2961835.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(357..1058)
                     /locus_tag="MIV85_002506"
     CDS             complement(357..1058)
                     /locus_tag="MIV85_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBY2961836.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(1336..2721)
                     /locus_tag="MIV85_002507"
     CDS             complement(1336..2721)
                     /locus_tag="MIV85_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBY2961837.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALVEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(3167..3589)
                     /locus_tag="MIV85_002508"
     CDS             complement(3167..3589)
                     /locus_tag="MIV85_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBY2961838.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            4067..6970
                     /locus_tag="MIV85_002509"
     CDS             4067..6970
                     /locus_tag="MIV85_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2961839.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISVSEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            7003..7449
                     /locus_tag="MIV85_002510"
     CDS             7003..7449
                     /locus_tag="MIV85_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2961840.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            7572..7874
                     /locus_tag="MIV85_002511"
     CDS             7572..7874
                     /locus_tag="MIV85_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2961841.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            8055..9461
                     /locus_tag="MIV85_002512"
     CDS             8055..9461
                     /locus_tag="MIV85_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBY2961842.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            9805..10863
                     /locus_tag="MIV85_002513"
     CDS             9805..10863
                     /locus_tag="MIV85_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBY2961843.1"
                     /translation="MGDKMRASVLYSVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            10962..11648
                     /gene="araD"
                     /locus_tag="MIV85_002514"
     CDS             10962..11648
                     /gene="araD"
                     /locus_tag="MIV85_002514"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBY2961844.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            11666..12313
                     /locus_tag="MIV85_002515"
     CDS             11666..12313
                     /locus_tag="MIV85_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBY2961845.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(12486..13853)
                     /locus_tag="MIV85_002516"
     CDS             complement(12486..13853)
                     /locus_tag="MIV85_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBY2961846.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(14043..14131)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            14559..16679
                     /locus_tag="MIV85_002517"
     CDS             14559..16679
                     /locus_tag="MIV85_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBY2961847.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKTIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKTCNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            16783..18036
                     /locus_tag="MIV85_002518"
     CDS             16783..18036
                     /locus_tag="MIV85_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBY2961848.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSKMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(18189..19250)
                     /gene="ytvI"
                     /locus_tag="MIV85_002519"
     CDS             complement(18189..19250)
                     /gene="ytvI"
                     /locus_tag="MIV85_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBY2961849.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            19524..20264
                     /locus_tag="MIV85_002520"
     CDS             19524..20264
                     /locus_tag="MIV85_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBY2961850.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            20276..22054
                     /locus_tag="MIV85_002521"
     CDS             20276..22054
                     /locus_tag="MIV85_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2961851.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            22221..23138
                     /gene="pfkB"
                     /locus_tag="MIV85_002522"
     CDS             22221..23138
                     /gene="pfkB"
                     /locus_tag="MIV85_002522"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBY2961852.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            23175..25094
                     /locus_tag="MIV85_002523"
     CDS             23175..25094
                     /locus_tag="MIV85_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2961853.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         9981 a         2842 c         4209 g         8257 t
ORIGIN      
        1 agttttaaaa taacttatac aataaaacat tatccaaata tcacaagata attccaaata
       61 aatatataga tatcactcct gtaataatag aaataccaat agatttaaac ttatatgcaa
      121 caagaagtac aatcataaaa gatataattt tagggttagc tatagataaa tatagactat
      181 ctccattaaa aaatacatct ttagcagtta aggaagtaag tattgctaca ggtataaatt
      241 tcatgatttt tttcaaaaaa tcaggcatct ctttttttga aaaaattaac ataggaagca
      301 ctcttggtag atatgtaaca atgtacattc caattataat aaaaaatata taattattat
      361 tcataagatt cctccttttt acagtaagat tcttctataa agaaaccaat taaagatgct
      421 aaaattgatg caactattat tactaaattg cttttgaata atgcatataa aataacagaa
      481 ataatgattg atgatataaa tactacaata taaatcttat tttttatttg agaaactatt
      541 aaagctataa acatagaagt caatatgaag ccagaaatag aactgtctat agatatactt
      601 tctcctaaaa atgctccaat aaaattagct aaaactgatg aaattaagca gaagaaatta
      661 agataaatag catttctatc agaccaattt ccagcagtaa atttttcata attaactgca
      721 aaagtttcat ctgttatagt atgacaaaat ggcaatataa attttggact tttatttttt
      781 atgtacatgt tcaaattaga actcattaga aaatgtctta agttaactat aaatgtagtc
      841 aaaacaatag atgttacact tgcaccagta gaaatcattg aagctgcaat gaattgagaa
      901 cttcctccaa atactaaagt taccattagt gctatttgaa aaggtgaaag accagatttt
      961 tgtaatagta ttcctcctac tatacctata ggtatataac ctaagaatat aggaattgaa
     1021 gcaataaagc tttcttttaa ttgttgagtt ctttccacaa taaatcactc cttttgtatt
     1081 aaatgtatta aagtattagt aaaacagaaa aatagattaa ttgtataatt gcaattataa
     1141 ttaaaaataa atttggatta atatataaaa tactatacaa caaatagata atcttaaacg
     1201 gttattaaat tttatctatt tgttattatg atgtaataat acatattaat ctctataagt
     1261 taattactat ctggtgtaat tttattttaa caacaaaaaa aaatacacac aattaaaata
     1321 ttgtgtgcaa tacaattatt ttttctcttc taatagtctt tttaatacgc tcaaaccagc
     1381 tttaagttct tctgtacttt ctgtagcaca tacagctatt cttattgcag aaattggttt
     1441 ttcttttcca acagcaaaac gttcagaagc atagacttgt acaccttctt taagtgcttg
     1501 tatctcaaat ttttctgcca ttattccatc aggtagaatc aaccatctaa atatacattc
     1561 ttcatttccc aaaagattat atccagataa atattgatta ataatcttgt ttcttcttct
     1621 tgcagattta cggcgtgcat taattaattt atcggcttca cctgatgtaa tcatgcgata
     1681 agcaatttct gttaaaaaat aagattgaga tagattaatg ttgtataatg cgcttgataa
     1741 tgcctctcga tactgtttag gtgtagagat atatgctagc cgtaaactag gtgcaataat
     1801 ttttgataaa ctcgtaatat aaattgtttg atttggcaga taggaagcca ctggatttaa
     1861 atgtgtttca ttaagtaaac tatgaatagc atcctcaata acaattaaat tgtatttaga
     1921 tgcaatattt gcaatcattt ttcgtccatt ttgtgacatt atatgtgtag ttggattttg
     1981 ataatctggt attatgtata gacctttaat attttcattt ttacaagcat ataatagtcc
     2041 ttcttcacta atctcattat cttcttgttt aattggaatt agttgaatcc caagcatttt
     2101 agctgctgtc tttattccag gataagttaa tgggtctaca cctattctat ctccatgttg
     2161 aaacaaacca gctaaaatag caacaattgc attttgtcca ccacttgcag gaagtaagct
     2221 atctgatgta gtttcaagcc cagctttata aattaatttg gcaatagctt ctttttgcca
     2281 tttagcacca tctctttgtc catattggaa tatagtttta aaatctattt ccttaattat
     2341 gtgtttaaac aaagtattca tttcttctag cgtgaaatct ggattcattg tgcccatttc
     2401 aataaatgta attttattat tactggacat caagaataga tttgaacgtg tatcataaga
     2461 tacaaaagtt ccacttcctg taactccact tattagacct tttttttcac aaattttaaa
     2521 agctctagag atagtactca cattaacatc taagaaatct gccaattcac gttggggtgg
     2581 taatttagta cctggtaata aaaatccatt gttgatatct tgttctagtt gttctacaag
     2641 cgccttatat aatatttgcc cttttgaagg tctctttggt ttccagttca taggataatt
     2701 ttcaaaagaa ttaattggca taagttttca cctcacatta ttaatttgat tttttcttta
     2761 tctaaaacaa taaattctaa agatacaaat aaaaactgat aggaaataat tctatcagtt
     2821 tttgtctttt aattgatttc aaatcttcct ataattttta taccttcttt atcataaaga
     2881 gggattgttt ttttaaatat attaaaattt ctttttcttg tatataaaac agcttcttct
     2941 ggtgtctttg gttggttatc acaatcgtac aaatttcttt tttttaacta aaagcaataa
     3001 tacataaaat tattattgct aatgatactc ttaatgtggt atatagtcat agtgtcacat
     3061 gtctatcaat agttttttca gtaattattg taacgaatag taggactcat aaaatactta
     3121 gaaatatgtt tttagataaa ttttaaatat ataatctaac ttatatctat aaattaacac
     3181 tattattctc caattccatt tctagttttt ttataaattt attaaattct tctggttgcc
     3241 tttttccaaa caatactctt acaagagctg aattgatttt tccaaatata ttcctcttgc
     3301 tctcactttc aataaaaata agttttgtat tttctaagtc aatatgtact aattcatatc
     3361 tagtaatagt actttctctt ttattgcttg tttttatctc atatactcta tttttttcga
     3421 aattagttat ttcaacctta aatcttttat tatttttttg ctgtacaaat gttcctactg
     3481 cttttttctc attaaaatta ggaaaattta gtcttgcaga ttttgtaaat atattaaata
     3541 tgtcttttgc agaatatttt aataaaactt cagttttaaa tgtattcata tcgttttccc
     3601 ttctgtatat aaatttaata tttataagtt aatttttaag ttaaaatagt ataatatgcc
     3661 atattaaatc atgttaaaac tatttatata gctaaaatct tacctatata agtatgtata
     3721 ctatcatata aaaataaaat cttaaaatag aaagggttaa aaacacagtt tattataatt
     3781 tttattgttg agtagatacg tactattata tatgattgag caagtttttc aatcataaat
     3841 ttataaagta ttttgcatta aaatttaaac aaagaattaa attatttaag attatgaata
     3901 actaatacat ttagtaaatt actaaatata caaaatgtaa atacttatca aaatgtataa
     3961 atacttatga catctagtta cttacagggt ttaagtagaa aaaaatatca aagtaagtat
     4021 ggcatgatag ttgcttatat atttatcaag aaaggagtta ttaagcatgg agttgagaga
     4081 taaacttgta aacatcataa atacagaaaa taaaaaagat ccattaacag atgttcaaat
     4141 agcaaagttt ttaagtacaa ctagagagaa cataactaat ttgagaaaag aacttaatat
     4201 aagtaattca aggcaaagaa gatatcctta tttaaaatca gcaatttcgg caatattaca
     4261 aaagaataag aatatttctg tatcagaaat tacaagggaa ttgatgacag aaggctttaa
     4321 tatatctaga agagttgtgg aggaactttt acctaaagaa agtttagaaa tggatgtagt
     4381 agaggaatct gaagaagaat cgaatgaccc atttgaaact ctgataggta ataaagggag
     4441 tcttagaaat gctgtagagc aggctaaatc tgctatattg tatccaccaa aagggttacc
     4501 aacgttgatt attggggaaa gtggagttgg taagagttta ttttctagac atatgtatga
     4561 gtttgcaaag caaaaaaaga tagtaaaaga aagctccaat tttgttgtat ttaactgtgc
     4621 tgattatagt gacaatccac aattattatt atctttgtta tttggatata aaaaaggtgc
     4681 atttacaggt gctgaatatg atacaccagg tcttgtagaa gaagctgatg aaggagtttt
     4741 atttttggat gaaatacata gattgcctcc aaaaggccaa gaaatactat tttctatttt
     4801 agatagggga aagtttagga gattaggtga aactaatgct gaaagaaaag taagtattat
     4861 gttgattggg gcaactactg aaaatgtaga gactaattta ttattaacat tcagaagaag
     4921 gataccaatg ctaataactt tgccaccatt acatgataga ttactaaaag agaaaataga
     4981 ccttatatac aatatctttc aacaagagtg taatagaata aatgcaaaaa tatttgtaga
     5041 taaaaatgtg attgaaatac ttgcactaaa aaagtttagt ggaaatatag gacaattaca
     5101 aaatatgatt caggttcttt gtgcaagagc ttttatgaag tttataaatt ccaaagatga
     5161 agatagtgaa tcgatagtag tagtagatat aaatgaagtt ttaaagctta aagattcttt
     5221 taaagatgct gcctttcaag agattgaata tacagagata agaaaatatt tgaaaaatgc
     5281 tatatttata ccatttaatt tagaagaatc atcagtaaaa ggaagtcttt taagtgatga
     5341 atatatatta ccagaggaca tatacaaaac aattgaaaag aaatattatg acctaaaatc
     5401 cctagacatt gaagatatag atatagagaa tattttatgg acttttattt taaatagatt
     5461 tgctgactta aagtttaatc tcgatagtaa tgaagaaatt ttttcaatga gtgatttaaa
     5521 tagttttgta agtgatagtt tagttaaact ggtaaaagaa cttatgaatg atatagttga
     5581 aaaaaatatg aatttagaag taaataaaaa tatgttcaaa tatctagcaa tacacttaga
     5641 agaagctata aaaagaatta agctaaatca aaagataata aatgtaaatt tagaaaaaat
     5701 aaagattgac ttttcaaaag aatatgaaat tagtaaaagt tttgcaataa aaattgagga
     5761 atcaattggt attaagattc cagatgatga aattggattt ataacactct acataaagtc
     5821 tgctctaaaa aatgaagtga aaaaagataa agtagggtta ataataattt ctcatggacg
     5881 tatagctaca gagactgtaa atgtagttaa agaactttta ggtgtaaagt ttcctgtggc
     5941 tatagatatg cctttagatg aaaaaccaat aaatatatac aataaggcag tagaactgtc
     6001 aaaaataata gaccaaggga aaggcatatt gtttttggtg gatattggtt cacttacaaa
     6061 cataggtcaa atagtaaata agagaaccaa tataagcact aaaactattg atagagtaga
     6121 cctcctaatg gcactagaag caactagaaa agtttctatg ggagaggaag aacttgatga
     6181 aatatttttt tctttgctaa aagataggat gggatataac tatgaattag aaaaacacat
     6241 agataaatca aatgcaattg taacattatg tcttactgga gaaggaactg ctaagtatat
     6301 aagtaaaacg ttggaagaaa agtatgataa cactaaatgt tatcaaatga gtgcattgga
     6361 tgaaaattta ttttgtaaaa ttgaaaatct aaaagagaca aacaatatat tagctattgt
     6421 tgggacaata aaccctaaga taccaggtat aaattttata ccctataata aagaactttt
     6481 caaaaatttg gatatctatc tatcaaaatc aaaacaacaa gatgacagac cagttaaatc
     6541 gtatgaaaga atgcttgatg aggatttagt gatttttgaa ccagatatat attttaaaaa
     6601 ggatttatta gaatatgtat gttcaattct tataaataaa gaatatgtag aaaaagatta
     6661 cttagattct gttttacata gagaagaaat gcttccaaca tattctaaag gagctatagg
     6721 tgtgcctcat ggagattctt ctactgtaaa tagtacaagg tttgtttttg ttaaactaaa
     6781 gaatcctatt gattggggtg taggtaatgt aaatttcata tttatgccag tttttcaggc
     6841 taatgataaa gagattgtta aaaatgttct tgagatacta aaagatgcag aatttatgaa
     6901 caatgccaat aagtgttttg ataaagatgc ttttagaagg attatatttg ataaatttaa
     6961 acatctgtag ccatagcaaa aaaattgaga ggagttagag taatgaatgt agatttaata
     7021 tcattgggtt tagaatctaa tgattatgaa agtgttattg aagaattagg aagtataatg
     7081 tgtaaaaaag aatatgtaaa agaaacatac ataaatgctg tcttggaaag agaaaggaca
     7141 ttaccaacag gtctagatat tggagaaatg tgtgttgcta ttccacatac agattcaaag
     7201 catgtaaatg agtctaatgt agctgtaggg atattgaaaa atcctgtaaa gtttaattca
     7261 atgatagacc caaaagatag acttgatgta gaacttgtat ttttattagc agtaaagaac
     7321 ccagattcac aagtaaaact gttaaaggat ttaatgtcag tttttcaaaa tataaagtta
     7381 ttaaaaaata taaaaaacgc atcaacaaaa gaagaagtag ctaaattatt ggattttata
     7441 gaaatttaat gtaggagaat tttataaata aaaaattaaa atttaaacaa tcaaagtaag
     7501 tattattttt ttaataggtt taatcttata taaaataaaa atttagagtg aaaaattagg
     7561 aggaaattat tatgaaacaa tttaatgtat tatcagtttg tggttcaggg acagttacat
     7621 catctatggt agcaggtaaa ttaaaagaag tactaggtaa taaggggatt tctattacta
     7681 caacagaagc tagaccaaca gaagcactaa atttagcaca atcaggaaga tttgacttta
     7741 taacatttac gagtccactt caaacaggcg attatggaat accaactata aatgcatttg
     7801 cttgcctaac tggtataggg gaagaggcat tctttgaaga agttttgact gttattgaag
     7861 ggatagataa gtaagttttg gagacgtgaa tttatagtat ttaaatcaat gatttagata
     7921 ctataataag ctaatattaa ctaaatattt gtggaaaaaa cattttatat gttgtcataa
     7981 attaaaaaat tataaaaata gtcacttaag tattaaatta agcttataaa tatttataag
     8041 taggagggaa aaagatgtta gaatttatga aatctataat cgatacattt ggttctgcaa
     8101 ttatagttcc aattataata ttcataatag caaagatatt taaagtaact actaagaaat
     8161 cgtttctttc tgctgtgtat gcaggagttg ctttacaagg ttttacactg attttaaatt
     8221 catttacacc aataataaca ccagttatca ataggatggt tgagagtaca ggagtaaacc
     8281 taccagtttt tgatgttggt tggcaagcaa catcattggt tgcattttca acaagtgcag
     8341 gtatgatata tttaggtctt ggtatattat tacaaacaat tttatttttg ataaaatgga
     8401 cagacgtgtt tcaaccatca gatttatgga ataactattc ttatatggta tggggagcaa
     8461 tggttatagg agtaacagga aattttcctt taggtatagc atgtatggtt ttattaaacc
     8521 tatatagttt attaatatca gagttagttg caaagagatg gtctagttac tatagatatc
     8581 ctaattgtac aataatagct atgcataatg ttgaagcttc tgtgtttgca gtatttgcag
     8641 accctatata caataaattg ggattaaata aaataaaatt aaatccaaaa gaattagaga
     8701 agaaattagg gtttttaggt gaaccaatta ctttaggtct ttttttaggt atgtttatag
     8761 gtatattagg taatatgacg agaataaata ctatggaagc ttggggagaa ataatgaaag
     8821 taggtatatc tacaagtgca gtgatggcaa ttttccctaa agtagcaagt atgtttgctc
     8881 aagcatttgc acctataaca gaagcagcta gaaagattat gcaaaaagct ggaaaccgtg
     8941 agtggtacat agcagtaaat gatgctgttg ggtatggtga acctgcaact ttaatatcag
     9001 gtcttatatt aattccaata atgcttgtaa tagctatggt acttcctggt aataaggtat
     9061 taccagttgt ggatttattg gcaattccat atatggttca aggtttagtt gccatacata
     9121 atggtaatat accaaaagta ttggtttcag gtataatttg gtttggatta ggattatatg
     9181 tttgtacatc tacagcacca ttatttacag atatggctac aaatataggt gtagctatac
     9241 ctgcaggagc aatgttaata acaagcttta atatactagg aaaacctttg atgggattag
     9301 ttttctttgc atttctaagt gcaaatccaa tttatatagg tctttcagtt gtaatttact
     9361 ttgttctatg ggcattgttt agaaagaaca aaacaagtat tcttgattat ttagaaaaac
     9421 aagcacttaa aaatgtagaa gaagagcctg tagcagttta agtttataaa aatgaaataa
     9481 gaataattaa aggagtttat aattgatttt atataagtat cagataatac ctgagaaata
     9541 tttaaatgaa atatagactt ctttttattt gataatattt gtaattataa tgcattgtat
     9601 ctttatagtt gagttttctg tataacctgc tatttaaaac atactctttt atatttatac
     9661 agtaatgtgg tttaatttta taaaatgtaa tctctactgg taaaagactt tgtatataag
     9721 gcatttgcct gaataaacca tttatctttt gtatggcata gatattgcta tatagaagta
     9781 tatagcatga aaggagatat ttatatggga gataaaatga gagcatcagt attgtatagt
     9841 gtaggtgatg tcagatatga aatggtagat ataccagaaa taacagatac gcaagtgctt
     9901 gtaaatgtaa aatatgttgg gatatgtggt tcagatttac ctaggtctat ggtaagtggt
     9961 ttgagtggaa atacaaaata tccattgatt ttaggacatg aattttctgg cgaagttgtt
    10021 aaaattggag aaaaagtaaa gcatattaat gtaggagata gagtagctgt tgcaccatta
    10081 gtaccttgtg gaaaatgtga ttattgtaat gaaggtaatt ttggcttgtg tgatgattac
    10141 aatataattg gaacaagagt aaatggagcg tttgcagaat atgtaagagt tccagaagaa
    10201 catattttaa aactaccaga tacattggat tatgaaactg ctgccggaat tgaaccagca
    10261 actatagctt atcatgggat ttcaaagtct aatattagag taggagatag tgtagttgtg
    10321 ttaggatgtg gtccaatagg tcagtttgtt atacaatggg caaaggtgtt tggtgcatct
    10381 aagattatag cagttgatat ttttgatgaa aaattagaac tttctaaact tctaggagca
    10441 aactatatac ttaactcaaa agaagtaaat gtaatcaaag aaataaaaaa aataacaaat
    10501 ggtggtgctg atgttgtaat agagactgct ggtagccgat ttacacaaga acaatctcta
    10561 tttgtagcaa aaaagagggg aaatatagtg tttgtaggta tatcacacac agaattacca
    10621 cttagtgcag acgctactga gtgtatatta cgtggagaac ttaccttgaa aggttcttgg
    10681 aattcatata caagccctta tcctggaaga gcatggactg caacattgga ttttatggga
    10741 aaaggtgaca ttatttttaa acccatgatt tcacataaaa taggtcttaa tgaagtgggt
    10801 gactttttaa gtaaaatgag caagagagaa attaatttca ataaaatcct agtagaaata
    10861 taaaaattta ataaaaaatt ctaaaagcaa ttaaatttta taactatgac attaaataaa
    10921 ataaaaataa ttttcttaaa taaaatatag gaggaagaaa agtgttagaa aatttaaaag
    10981 aagaagtatt aaaagcaaac ttagaattac ctaagaaaaa gctaattact tatacttggg
    11041 gaaatgtaag tggaatagat agagaaaaag gattagtggt gataaagcca agtggtgtag
    11101 agtatagtaa tatgactgta gaagatatgg ttgtagttga tttagaggga aatatagttg
    11161 atggcaaatt aagaccttct tcagataccc cgactcatct agttttatat aaagagtttg
    11221 aagaattggg gggaatagta catacacatt caagttgggc aacaatttgg gctcaaatag
    11281 gaaaatctat accatcttgt ggtactactc atgcagatta tttttatgga agtataccat
    11341 gtaccagaaa aatgactaga gaagaaattt gcaatgaata cgaaaaggaa actggaaatg
    11401 taatcattga agaatttatg ggaagaaatc caattcattg tccaggaata attgtaaatg
    11461 accacggacc ttttacatgg ggaaaagatg caaatgaggc tgtacacaat gcagtagttt
    11521 tagaagaagt cgcaaagatg gcttattata cagagttaat gagtcctgat aatattatgg
    11581 ataaggttct tatgaataag catttttcaa gaaaacatgg aaaaaatgca tactatggtc
    11641 aaaaatgatt atctggaggt gaattatgct agactcttta aaaggtaaaa ttgtggaaat
    11701 agcaattaaa gcagagcatt atggtttatg taaagaaaag actggtaatt ttagtattag
    11761 agataaggat actggatata tacttataac cccatcaggt gtaggaagag aagaattaaa
    11821 agttgaacat atttgtgtat tggatttgga tggaaatgta atagaagttg agaaaggtat
    11881 taagccaagt agtgaggtat tgatgcatat tgaaatatac aaaacaagag aaaatataaa
    11941 tgccatatca catactcatt ctttatatgc aacagcattt tcagtagcaa agaaaccaat
    12001 tataccaatt gtatatgaat cagttaatta tggcggttat gtagatattg ctccatatga
    12061 aagaccagga actttaaaat tagctaagag tgtttcaaaa ttactgatag atacagatgc
    12121 atgcttatta gaaagacatg ggttgacaac tgtaggtaat gatttagacg aagcattatt
    12181 aaaatcaaga tatgtggaag aggtagcaga aatatactat aggtctttag tattaaatca
    12241 atttaaagaa cttgaagtag tagatgttga tgagtttaaa tcttggaaat acccagaaga
    12301 aataaagttt taatctaaat aattttcatt gaagtggtta attaaaatat atgtattatt
    12361 tatatcaatt actatgtttt attatgttaa ttaccgtatt ttgcaaatat atttattaca
    12421 ttttttcaaa aaaatataga atccgaaagc catataaaat tgacttggga ttctatactt
    12481 tttatttatg catttttctt tatctgattt tctggagaat ttatatgttc aaaatatttt
    12541 ttagtttcag atactattat aggtgataat gcaagtaaag ctataaggtt aggtattgcc
    12601 ataagcccat ttacaatatc agcaattatc caaacaactt ctaactttaa gaaagcacct
    12661 aataacacca tagccacaaa tacagttcta tacccattca tgccttttac accaaacaga
    12721 aattcaaaac atctttctcc ataataactc catcccaaaa ttgtagtaaa tgcaaataat
    12781 gttaaactaa ctgtaagtaa tattggtcca aatgtaggaa ttgctccgtt aaaagctgct
    12841 tgtgtcataa cagctccatt taggtctgaa caccacactc ctgaaataac aagagagaat
    12901 ccagtaagag tacagattat aatagtatct ataaaagtac ctgtcataga tataagacct
    12961 tgttccgctg gccattcagt tttagcagca gcagcagcta ttggagcact acctagacca
    13021 gactcatttg aaaatacacc acgagcgata ccatttctaa ttgccagtga catagttgct
    13081 cctaaaaaac caccagtagc agcagtaggt gtaaatgcac ttttaattat taacataaaa
    13141 gtttcaggga ttttattcca aaaagatatt aaaatgattc cacagattac aacatatata
    13201 actgccataa aaggtactat tttagtagct acattagata tacttttaag tcctccaaat
    13261 acaaccaaag ctacaaatac tgctaataca acccctgtaa ttctagggtc tatcccgaaa
    13321 ctattattta ttgcatctgt tattgaattt acttgagtaa aagtaccgat tcctaaaagt
    13381 gcaactagta taccacttat agcgaaaaat attgcaagag gtctccattt ttctcccata
    13441 ccatttacta tgtaatacat tggcccacca gacacttggc catttttatc tttagttctg
    13501 tattttattg caagaacacc ttctgaatac ttagtagcca ttccaaagaa tgctgctatc
    13561 cacatccaaa aaagtgcacc aggtccacca gctttgatag ctgtagcaac accaacaata
    13621 ttaccagtac caactgtagc agctagagca gtacataagg ctgcaaaact tgaaacatca
    13681 ccactacctt tgttttcagc agagaatatt aacttaagag ctcttggcag tttagttatt
    13741 tgaacaactc caagcttaac agtaagtagt ataccagtac caactaatag taccagtagg
    13801 ggtggtcccc aaataaaagc atcaactttg tttaaaatat caattagatt cataaaaaca
    13861 ctccctcatt ttttttgctt tacataatca atagaatttt taatgaagta attgacagga
    13921 aataagtata atttattaat aatttctagt gtaataaaaa aagctaaatc taaaaaagat
    13981 tcagctctgg atgtacacta attagcaacc aaaataaaag tattagtaaa tactgttttt
    14041 ggtagataat ccctgtcctt ttgcctgaga gattgagcat aaaagccttg ccccttcggc
    14101 gcccataatg ggtctctcca gagttccgta aattttacag tcctactttt aaaagtacct
    14161 gagagtgtta ctccttcggt gtgctatata gcaactcttc tataaaatct taaccggata
    14221 ttgatttgtc atagcttatt gtattaataa tattaatata agtttttatg ttttgtcaac
    14281 taaaaaatta aaaaacaaag aaaaaatata aaaatgtaag cctatttacg aattataaac
    14341 ttagaaagat gagtaatata cgtgaaaatg aattttgtaa tacacataca aatgaagtgt
    14401 aaaataagtt ctaaataaaa aaataataaa atcttaaata attaattaga tatgattaaa
    14461 ttatggtaat attatagtta cgatattaag aaaagttcta tttagttaga ttttaagcgt
    14521 aatatgagat tatgtataga gaaaggatgt atttttagat gggaaaaata ttagtgctag
    14581 cagaaaaacc ttctgttgga agagatatag caaaagtttt agggtcaaaa aatgaaaaaa
    14641 atggttatat agaggggcca aagtatgtga taacttgggc actaggtcat ttggttacac
    14701 ttgctgaccc cgaaagttat ggagaaagat ataaatcatg gagcttagaa gacctgccaa
    14761 tacttcccaa gcaccttaag actgttgtaa taaaaaagag tggaaagcag tttaatacag
    14821 ttaaatcgca aatgaataga aatgatatag atgaaatagt tatagcaaca gatgcaggtc
    14881 gtgaaggaga acttgtagca aggtggataa tagaaaaatc acaggtaaaa aaaactataa
    14941 aacgtctttg gatttcttca agtacagaca aagcaataaa agacggattt gcaaaattaa
    15001 gaagtggaaa agaatatgaa aatttgtatt actcagcaat agcacgagca gaagctgatt
    15061 ggattattgg aataaatgca accagagctt tgacaacaaa gtacaatgca cagctttctt
    15121 gtggaagagt acaaactcct actcttgcaa tgttgcttaa aagagaagaa gaaataagaa
    15181 atttcaaacc taaagagtat tatggattag aattaattgc tacaaaggga aattcagata
    15241 taaaatttat ttggaatgat aaaaacaata attcttcaac ttttagtaaa gaaaagatag
    15301 aatccacatt aaaaaaagta aaaggtgtag acataaaaat atctgaagta aacaagtcat
    15361 ataagaaaaa atattcacct gcactctatg atttaacaga attacaaaga gatgcaaata
    15421 aaatgtttgg attttcagca aaagaaactt tatctataat gcaaaaactg tatgaacatc
    15481 ataaagtact tacttatcct agaactgatt ctagatattt aacatcagat attgttggaa
    15541 cattaaaaga tagaataaaa gctgtaaata ttagtgatta ttcaaagact tgtaataaat
    15601 tattaaaaag caatattata gctaataaat cgtttgttga caattcaaag gtaacagacc
    15661 atcatgcaat aataccaaca gaacagaagg tattcatgag tgattttagt gacaaagagc
    15721 gaaaaatata taatcttgta gtaaaaagat ttttagcagt actatctcct ccttttgaat
    15781 atgagcagac aactataagt gcaactgtag aaggagaaat atttaaggct aagggaaaca
    15841 aagtaataaa tttaggttgg aaagaaagtt ataaagatat tgaagatgaa gatgagtatg
    15901 aaagtatacc aaatatttta gaaaaagatg tacttaaggt caagggatta aagataactt
    15961 caggaaaaac aaatccacca ccatacttaa atgagggaac attattgact gctatggaaa
    16021 agaatggtct agggacagtt gctacaagag cagatataat agaaaaatta ttcaattcat
    16081 ttttaatgga aaagaaaaat aaagatatat atataacatc aaaaggaaga caattattag
    16141 atttagttcc agtagactta aagacaccag aacttacagc ttcatgggaa aagaaattat
    16201 tggatatttc aaagggaaaa cttagtaaaa atacattcat aaatgacatg aaagattatt
    16261 caaaagatat tgtactagaa gtaaaaaata gtgataataa atttaaacat gataacttaa
    16321 ctaaaaatag atgtccagaa tgtggtaaat ttatgttaga ggtaaatggt aaaaaaggta
    16381 agatgttgat ttgtgaagat agagagtgta atactagaaa aactatatca caagtaacca
    16441 attcaagatg tcctaactgc cataaaaaat tagaacttcg tggagaaggt gaggggagaa
    16501 tcttcacttg tagttgcgga tacagagaaa agttgtcgtc tttcaacaag agaaagcaag
    16561 aagaaaaaca gaaggcatca aaaaaagatg ttaatcaata tttaaaaaat caaaataaaa
    16621 atcaagagac atttaataat ccatttgcag aagcattagc taagctaaaa aacaaataat
    16681 tttaaagtta ttattataca caattataac tttaactgta tattagttat atgtactgat
    16741 ataatatagt gtatagttta ggcatgaaag tagggctgtt aaatggattt aagtggcata
    16801 tttaaatact attgtaaaga gtgtgaaaat acatggaata attcgagtgt tgaattattt
    16861 gagaatatag aaacgtatag taaagattca caaaaaaaga gggaaaaaga attagataaa
    16921 ttgctaaata caatatcagt tcatttagag aggtatccaa gtgatgctgt attgagaaaa
    16981 atgtgggtaa aaaagggcga ggttttctta caaaagacat tggaaaaaga aaatattttt
    17041 aagttagaaa aaatggatgt agaggataga aaaaaatttt tagatataac aaaacagttt
    17101 attagagatg ctagaaaatt tgatgatgat ttacctatag gtgatattat gcaagctatg
    17161 aggaatgtat ggatttcaaa tgcattacaa ttattatttg gtaaagaagt atattattca
    17221 aaagctaact ttgcatatag tatgttatat ccatatactg ataattattt agacaataca
    17281 aatatagata aaaatgataa gattttattt aataactggt tagaaaaaag gctcctggga
    17341 gaacacatta aatctaagga ttatcatgaa agtaaagtat ctaaaatgat agattatatt
    17401 gaaagtgtat accctagaga aaagtttaca gaagtttatg aatcgttatt attaatattt
    17461 aaaagtcaag taaatagttt aaaacaacat ggtaaggaaa atcatttgtg taaagaagat
    17521 ttattatcca tttctattga aaaaggaggt tcatccgttt tagtagatgg atatttaata
    17581 agtggattga tgacaaagga agaaatagag ttttgtatag gatatggatt tttattacaa
    17641 atatctgatg atttacaaga tataaaagaa gatttaaaat acaaccataa aactattatt
    17701 acagagatgt caaaagaggg tactttagat aaagttgtaa ataaactaat aaattttact
    17761 attgagttaa tagatagttt taaaattaat aataaaaata aatctgtaat aactatgata
    17821 aagaatgatt gcttaatgtt aattttattt tctgtagttt ataatgctga atttttttct
    17881 gtaggatata taaaagaagt agagaaattt attccatata caatagatta ttcattagag
    17941 attgaagaaa aaataaaaga aaaatttaaa aatatagatg ttttaaataa tgaaaatgaa
    18001 tataaagaaa tgattgatat tatttgtgca gagtagaaaa aaagggagtg tcttagaata
    18061 gactttttag tttatgaggc actctttttg tataaaatca aatgtatttt catcatttta
    18121 ataattaaaa agagcttatc cctatttgag aaagcccttt ttaatttaat aaaaatgtca
    18181 aggttaaact atttaaatgc agtaataatc ccattatcat gtaagttttt tatgattgta
    18241 gctgcgatag ggaatccaaa taatccagct attccaaata gttgagctcc aacaaacata
    18301 cacattaatg ttattaaagg atataggcca atttggtgtc ctactacctt tggttctaat
    18361 atttgtctaa caacggttat aattatgtat agtattaaaa gtcctattgc taaattaata
    18421 tttccattaa tgagtgagat aatcatccaa ggtgtcaaaa tacttcctgt acccaagact
    18481 ggcaaaatat caacaagtgc tatgatgaca gatatagtaa atgcattttc aacctttagg
    18541 atagtaagtc caataagtag ttctatgaat gtcactgata gtagtattgc ataggctttt
    18601 agtagtttta aaagagcatt aatactgcta ttttttatat ttattatcat aaattgactt
    18661 ttttctggaa attgttttaa gataaagttt actatttttt gatagtcaaa agtaaagaaa
    18721 aaagaagcaa ttaaagtaat aataagtttt aacataaatg caggtgtttt acttgcaata
    18781 ctagcaatag cattgagtgc atttgttgaa atagaagcta ctaaagacat catagattga
    18841 cttatattat cccaaccaag tattaatgct aggttaacat taggtgtact agcatctatc
    18901 tttgaaaata aagtatttag cgttggttgt atacttgatt tatatatttc aggaagtcta
    18961 aaaaatacat cacttacact tgcaaatatc ttcacaccaa agctaactaa taaaaatata
    19021 cacaacccat aaaaaattaa aagtattact atagaaataa gtgtacgatt taaatttgta
    19081 ttatttgtaa taagtcttat aataggtctt aagatggatg caatgataaa actgattaca
    19141 aaaggcatta ataatggcaa taagaatttt aatacaatat atacaatact tgttattaaa
    19201 actacatatg taaatttaat tataaaattc ttttgctttt gaatatccat aatataaaac
    19261 ctccaatgta tttgatatta ttctaaatat ggtctttttt acagaaaata tactactgta
    19321 tattgattat aaactataaa gcttatgtaa agtaaataaa ttatgtaaaa tttaggttaa
    19381 ttttgtataa agagatactt ttatatttta caattaataa ccaaatacta aaaaatattt
    19441 taaataaaga acttaaaatt gtgataaaat taatttatag atattaaaaa aagtataata
    19501 tatggttttt aagaggtgct aagatgaaaa attttagaga tttaggtggg aacaaaactg
    19561 aggatggcag aactgtaaag aagggattat tttataggtc tgcaaaatta tcaaatctaa
    19621 gtgaaaatga tataaagatt ttaaaagagt taaatattaa atatatattt gattatagaa
    19681 gtgatgaaga agctcgtaaa catccatcaa caataatatc aaatataaaa aatataagaa
    19741 taccagcaat gagagagcta gaagaatcag gaggaagttt tggttctatt gaagatatga
    19801 ttgatggatt gtttgaaaaa gatggtgcat ttaatatgtt aaataatagt tactataatt
    19861 tgcctataaa taatccgtca tataaaaaat tagtagaact tataagagac tattctaatt
    19921 taccaatatt aaatcattgt acagctggta aggatagaac tggtgtgggg agtgctataa
    19981 ttcttatgat tttaggggta tcgagagaga atataatgaa agattatcta aaaagtaatg
    20041 attttgcaga taaagagata gaaagattta tagaatataa gcctaaattt aaggacattc
    20101 caaaagaaaa tttgaaatat atatttggtg taaatgaaga gtatatgaaa actgcattta
    20161 gaagaattga tgaagaatac attagtgtag aagcatattt atatggagaa tttaatttaa
    20221 ataaagaaga aataagaaaa ttaagaaatc aatatctaga gtaaaaggtg agtttatgag
    20281 tttaaatata acagcaagac agataaatat aataaaaata ttgttaaatt caaaagatac
    20341 aattagtggt attgccttaa gtcaagagat aggatgttct tcaaaaacta tacaaaatga
    20401 aataaaggat attaataaac aacttagaaa tggtaaaatt ttgtcaataa gaggagttgg
    20461 ttataaacta gaaggaagtt ttgatgaggt aaatctaaat agcaatctct atgatgatgt
    20521 agatagagta gaatatataa tcagaaaaat attaacctta agtaatgaag aaaaaaatac
    20581 tataaaactt gaagatttag ccgattctat gtatgtaagt gtttcaacag taaaaaatga
    20641 tttaaaagaa gtaaaaagaa tgttggaaaa gtattcaata tcagttaaat ctaagcataa
    20701 acaaggtata tgtgttttag aaagtgaaga taagatatta aattgtatag ttgacttaag
    20761 caataagaga gataatcaat tgagtttaaa tgatttttta aatgatgata taaaggaaag
    20821 aaaactatta ataaaaaaat tattattaga catattaaat gaaaatggat tagtattaac
    20881 tgatatagaa tttaagagtg tgttaaataa tatattagtt atgttaagca gacataagta
    20941 taatgaaaaa gaatttatag agaattatat agaaaattat aggagcaaaa gaagctcaat
    21001 tttagaaaat gaacaaaaca aagaaattat aataaattca ataaaaacat tttgtaaaaa
    21061 tttaaaatta gctacatcaa tagatataag taatgataag gtatttgaag agtttttata
    21121 taagcatatt agtagtttat gtaaaaaaat aaagttaggt ataaatcaat cacctataat
    21181 ggctcaagat ataaaaataa aatatccatt tgcttttgaa ctagctaata tagctaaaaa
    21241 gacaatagaa aaagatttga agatagaaat taatgaagat gaagttgcaa acatagctct
    21301 acatatagga ggagcagttg aaagagcatc ttataataat aaagataagg ttttcaaaac
    21361 tataatagtt tgtacttcag gcataggcac atcaatgtta ataaaagcta aattagagaa
    21421 tatatttaag gaaaaattag aaatactaaa gattattcct tcatacttag ttgaatatat
    21481 aaaagttata gatgttgatt ttgtaatatc tactgttcct attgaagtag gagatgtgcc
    21541 agtaataaat atatctccaa ttttaagtga gaaagaaatt agattaattg aaaaatatat
    21601 agaaacagga aatatatacc tagatttaga tataaaaagc ctgtttgata gtgaattgtt
    21661 ttttactgat ttggtgttta aaaggaaaga agaagttata gattttatgg caagtaaact
    21721 tgtacaaaag ggctatatag atgaggatat gaaaaaatct tactttgaga gagaaaaaat
    21781 agcaacaaca gaaataggga atatggtaac tataccacat ggagctattg gaaaaatttt
    21841 tgataataaa atagcaattg gtatattaaa gaagcctatt tcttgggaaa tatcagatgt
    21901 tcgtttaata ataatgttag cccttgataa agataaaata ttagattatg aagtaatatt
    21961 ttcaaaaata tataaaagag tagattctat agcaaaagtt ataagtatat gtgaaaatag
    22021 tagttttgaa aaatttgtaa atttatttaa ttagatgggt agtattgtat atacacctgt
    22081 aaatttggat aatataaaac taaataagat aaaaacgata aatttctctt ttaattaaga
    22141 gaaatttttt gactttcaag gatattaata taaagttaag atataaacat aaagcaaata
    22201 aataaaaaag aggtggcaat atgatttata cagtgacatt aaatccatca atagattata
    22261 tagttaagct agatgagcta aagacaggaa gtacaaatcg tgtaaaagaa gaatacgttt
    22321 atccaggagg aaaaggtata aatgtatctc gcatacttaa ggaacttgga aatgataata
    22381 catctttagg ttttataagt ggttttactg gagaatatat aataagaaca ttggaagaaa
    22441 aagaattgaa gacagatttt ataaagataa aaagtggttt ttcaagaata aatgtaaaaa
    22501 taaaggcgtt aaaggaaact gagattaatg gacaaggtcc aaatatagat gatgaagaca
    22561 ttgatacttt atataaaaaa cttgataagc taaatcaaga tgatatttta atattggcag
    22621 gaagtatacc atctacttta gatgaaaaac tatacgaaaa tataatggct agattagaaa
    22681 aaaagaatat aaaagttgta gtagatgcaa ctaaaaatct tcttcttaat gttttaaaat
    22741 acaaaccttt tctaattaag cctaataacg acgaattaga agaactattt ggtgttaaat
    22801 taaattcaat tgaagacatg gtaaaatatg ctagaaggtt aaaggaaatg ggagctataa
    22861 atgtcttggt atcaatggga aaagatggag cattgttgat tacagaggaa gatgaagtgc
    22921 ttataagtga tgttccaaaa ggaaaagtaa aaaattctgt aggagcaggt gattcaatgg
    22981 tagcaggatt tatatctggg tatttgaata ctgggaaata tgattatgct cttaaattgg
    23041 gagcagcttc aggtagtgca actgcttttt catatgactt agccaaaaga gaatacattg
    23101 ataaattggt aaatgaaata tctgtaaaga agttttaaaa tattaaaaaa tatatagaaa
    23161 ggtaattaat atttatgaaa attatagatt tattagatga aaagtcaatt aagttaaatt
    23221 taaattcaaa aaccaaatca gaagcaatag aagaattagt agatttggtc gcaaatagtg
    23281 gaaatttaaa tgataaagaa aactacaaaa aagcaatttt ggctcgtgaa gaaatgagta
    23341 caacaggaat tggagaaggt gtagctatac ctcatgctaa aaattcttca gttactaaag
    23401 cttgtatagc agcagcagtg tcaaaagaag gtatagatta tgaatcgttt gacggaagtt
    23461 tatcaaatct attttttatg atagctgcac cagacggagc taacaatact catcttgaag
    23521 tattatcaag attatctaca atacttatgg atgaagactt tagaaataaa cttataaatt
    23581 caagctctga aaaagaattt aaggaaataa tagataaaaa ggaaagagaa aaattcagtg
    23641 aagaatatca agatgagaaa gtggctgaaa aaaatataat agatactaaa gagaatgatg
    23701 ctaataagta tcctaaggtt ttagcagtaa cagcatgtcc aactggaata gcacatacat
    23761 ttatggcagc tgaaagttta aataaaatgg cagaaaacaa aggtgtatca ataaaagtag
    23821 aaactaatgg ttcagcaggt gttaaaaata agcttacaaa agatgaaata gaaaatgcaa
    23881 catgtataat agtggcagca gataaaaatg ttgagatggc tagatttaat ggcaaaaaag
    23941 tcataaaaac taaggtggct gatggtatac acaaagcgga agaacttata gacaaggctg
    24001 taaatggaga tgctccaatt taccatggag gagatggaag tcacaacgaa tcaaatgaag
    24061 aaagtgaaag tggatttaga aaagtataca aacacttaat gaatggtgta tctaatatgt
    24121 taccatttgt tattggtgga gggatactta tagcgatagc ctttttactt gatgattata
    24181 ctattaaccc ttcaaacttt ggttcaaata cacctatagc agcatttttt aaaggaatag
    24241 gagataaagc ttttggattt atgttacctg tacttgctgg atatatagca tactctatat
    24301 ctgatagacc agcgtttgtt gtaggatttg taggaggtgc tctagcaggt gatggtggtt
    24361 caggcttttt aggtgcacta cttgcaggtt ttatagcagg ttatttagta gaagggctta
    24421 agaaaatatt tagtgtacta ccagcttcat tggaaggaat aaaaccagta ttgttatatc
    24481 ctttacttgg aacacttttg atgggaatta taatgacatt tttagtaata cctccagtta
    24541 cagcaattaa taatgcaatg gttggatttt taaatggttt aggtggaact tcaaaaatag
    24601 ttttaggatt agtattaggt ggaatgatgg ctgtggatat gggtggacct gtaaataaag
    24661 cagcatatgt atttggagtt gcatcacttg aatcagggca gtttgaaata atggcagcag
    24721 taatggctgg tggtatggtt ccgccacttg ctatagctct tgcaactaca ttttttaaga
    24781 atagatttac taaagaagaa agagattctg gtaaagttaa ttatgtaatg ggattatcat
    24841 ttgttactga aggagctata ccttttgcag ctggagaccc acttcatgtt ataccagctt
    24901 gtgttggagg ttcagcagtg gcaggagcac ttagtatgtt gttcaacgca gctcttcgtg
    24961 cacctcatgg aggagtattt gttataccag tggttaccca tccatttgca tatatattag
    25021 ctatagctgt aggtgctttg gttggaatga tgcttttagc attacttaaa aaaccattaa
    25081 atcaagaagt atagcaatta aaggatattc aagaacttaa aatatgatgt tttataaaaa
    25141 ttaatatatt gctgaattat tttaaaataa ggattttatg aggctgttat ataacgattt
    25201 gtaattgtta tcttgacagt cttttatttt tatataagta aaataagtgt gttttgcttt
    25261 atttgtattt aaattgtttt taagttaga
//
LOCUS       DAGQVA010000054        25027 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.054, whole genome shotgun sequence.
ACCESSION   DAGQVA010000054 DAGQVA010000000
VERSION     DAGQVA010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25027
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.054"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            132..752
                     /locus_tag="MIV85_002524"
     CDS             132..752
                     /locus_tag="MIV85_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBY2961854.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(918..1454)
                     /locus_tag="MIV85_002525"
     CDS             complement(918..1454)
                     /locus_tag="MIV85_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBY2961855.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(1567..2241)
                     /locus_tag="MIV85_002526"
     CDS             complement(1567..2241)
                     /locus_tag="MIV85_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBY2961856.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            2444..4318
                     /gene="asnB"
                     /locus_tag="MIV85_002527"
     CDS             2444..4318
                     /gene="asnB"
                     /locus_tag="MIV85_002527"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBY2961857.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(4410..5846)
                     /locus_tag="MIV85_002528"
     CDS             complement(4410..5846)
                     /locus_tag="MIV85_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBY2961858.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            6175..6753
                     /locus_tag="MIV85_002529"
     CDS             6175..6753
                     /locus_tag="MIV85_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBY2961859.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            6792..7370
                     /locus_tag="MIV85_002530"
     CDS             6792..7370
                     /locus_tag="MIV85_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBY2961860.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            7456..8085
                     /locus_tag="MIV85_002531"
     CDS             7456..8085
                     /locus_tag="MIV85_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBY2961861.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            8075..10834
                     /locus_tag="MIV85_002532"
     CDS             8075..10834
                     /locus_tag="MIV85_002532"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBY2961862.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            10921..12483
                     /locus_tag="MIV85_002533"
     CDS             10921..12483
                     /locus_tag="MIV85_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBY2961863.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            12484..13620
                     /locus_tag="MIV85_002534"
     CDS             12484..13620
                     /locus_tag="MIV85_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBY2961864.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            13684..14760
                     /locus_tag="MIV85_002535"
     CDS             13684..14760
                     /locus_tag="MIV85_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBY2961865.1"
                     /translation="MKYFDYICKDDLEKIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNRHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            14738..15976
                     /locus_tag="MIV85_002536"
     CDS             14738..15976
                     /locus_tag="MIV85_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBY2961866.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            16030..17118
                     /locus_tag="MIV85_002537"
     CDS             16030..17118
                     /locus_tag="MIV85_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBY2961867.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLISKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            17146..17937
                     /locus_tag="MIV85_002538"
     CDS             17146..17937
                     /locus_tag="MIV85_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBY2961868.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(18052..18606)
                     /locus_tag="MIV85_002539"
     CDS             complement(18052..18606)
                     /locus_tag="MIV85_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBY2961869.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTHKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            18802..20004
                     /locus_tag="MIV85_002540"
     CDS             18802..20004
                     /locus_tag="MIV85_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBY2961870.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            20061..21041
                     /locus_tag="MIV85_002541"
     CDS             20061..21041
                     /locus_tag="MIV85_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBY2961871.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            21289..22242
                     /locus_tag="MIV85_002542"
     CDS             21289..22242
                     /locus_tag="MIV85_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBY2961872.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            22232..23188
                     /locus_tag="MIV85_002543"
     CDS             22232..23188
                     /locus_tag="MIV85_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBY2961873.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            23185..23940
                     /locus_tag="MIV85_002544"
     CDS             23185..23940
                     /locus_tag="MIV85_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2961874.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            24032..24997
                     /locus_tag="MIV85_002545"
     CDS             24032..24997
                     /locus_tag="MIV85_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2961875.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         9846 a         2634 c         4270 g         8277 t
ORIGIN      
        1 taattatacc ttaactgtaa acttatatag attatttact ttttaatatt agattcattt
       61 tttgagattg gtatataata aacatataga gtatataata atagttaaag ttaaaaaagg
      121 ggaaaagcaa tatgcagtat atacaagaac tacttgattt gactcaaaat tattgggtgt
      181 tagccacaat aatcggctta ttaagtgcat ttatagaaag ctttatacca gccttaccac
      241 ttgttgctat agttacagca aatgctgcaa tacaaggatt atttattgga tgtttgttat
      301 catggattgg ctcaggactt gggacaactt cattattctt attaataagc agatttaatg
      361 atagtaagct ttttaataag ttgagaaata gtaaaactga aaaagcaata agttggatgg
      421 ataaacaggg atttaagtta ttatttatag cgtatgcctg tccatttatg cccggttgtt
      481 tagttactat cgcatcagct tttggtaaaa aagatttaaa agattttgtg ccagcaatgt
      541 tggcaggaaa atttgtaatg tttatagtta taagttacgt ggcaagtgat atagaaggtt
      601 ttataacaag tcctttaaag atagcatcat ttatattatt ggtgtttttg tcatggaaga
      661 ttggaaatag agtaaataaa aatcttgaaa atcataatta tgatttccat cataaaaaac
      721 atcacaatga taaagatgat aaaatgattt agcttgtacg aaataaaacg tatcttaaaa
      781 tgatttagta ctaaattatt ttaagatacg ttttattttt tgtattaagg tacaaaattt
      841 ttagttcttt tgtaaactaa aatatataaa acttatttat acttagttca aaatattgtt
      901 atttattttt tctacaacta taataaaata taaaattgat atccaatcaa aaaaataact
      961 atgaaattta atagcttaga tatgaatttt tctgtttttg agttagtttt tataggtagt
     1021 aaagaaatgt ttatggtaat gggataaaac aattcaatac cttctttagt aataaggtca
     1081 agacacaagt gagatagata tcctattata aacccactgg acaaacatga gaaaactata
     1141 ttattgttag tgaagattgt cagagattta aaaaaactat aaataagtaa taaggcaatt
     1201 agactgtgag taaaccctct atgtctaaac ctacttccaa ataatttgta tattaacata
     1261 aattttttac ttatgtaaga acctctcata tctatatctg gaaataaaga acctaaatat
     1321 gcaaaataaa tataaattat aattaatact attttatatg caatatcgta tttaactagg
     1381 tatagattgt ttataaaggg gagtatcaaa agtgcgaata tataacctcc cctttcatgt
     1441 gtttctttta tcatataaaa atcctcctga atcgtcacta taaacattat attggtaaat
     1501 ttagactatc ttttattata ttatatagca aacataagtt tttttcaaaa ggattttaat
     1561 atttaattaa tcttgagatt ttaaattttt gtaattttct aaagcaccat tccaatttac
     1621 tacattaaac cagttgtcaa tgtattcatt tcttctattt tgatatttta aatagtaagc
     1681 atgctcccaa acatcaagtc ctattatagg agttaggttt ttacttacag ggctatcctg
     1741 atttggagta gtcataatag ataatttgcc atctttagta gctacaagcc aagcccaacc
     1801 agaaccaaag acatctaaag cagatttttg gaactcttgc ttaaattttt caaaagaacc
     1861 aaagtctcta tcaatagctt cttttaaaga ttcagaaggt atggtttttt ctggcgtcat
     1921 tatatcaaaa aagaatttat gattataagc tccacctgca ttatttctta cagttgtagc
     1981 aatatcttta ggtaaagaat ctaaattttg caataattca cataaagaat aattataaag
     2041 ctcaggatat ttttcaagag cagcatttaa tttatcaaca taagcttgat aatgcttatc
     2101 atgatgcagt ttcattgttt ctttatctat ataaggttca agtgcatcat atgcataagg
     2161 taatggttta accttaaatt tgttattttc aggtgtaaaa gcaaatgaag ttatgcactg
     2221 tgagattata aataaagaca taataactgg tattaatatt tttttcttca taaaaatcac
     2281 ctcctaatat agtatttcta gaaataaaaa aaatatgaaa tattaacaga taatttataa
     2341 gaatttaata gcaatttcat tttaaattga ataagtttta aagccaaaga caaaactatg
     2401 aaatatagaa taagactaaa ggacagaaag gaattttgat tatatggacg gcaatatttc
     2461 aatttattat aaaggtgata tatctaaaaa agaagatatt aaatttaaaa taaaagaatc
     2521 tgtaaataat acaagacttt ctagtagaat agagtataag gatgaggaaa aaacttttga
     2581 ttttgaaaga tttaatgtaa ttgatgctat ttatggaaat aaaccatttg aaaaagatgg
     2641 aaaagttatt gtttttaatg gaaatatata taactatcat gaaataaaag aagaattaat
     2701 taaaaaagga cacaatttta ctacaaatga tgatattgaa gtcttattgg catcttatat
     2761 agaatttggt aagaattgtg tacataagat taaaggaatg ttcaacttta taatctatga
     2821 tagagaaaat gaaagtatat ttggagcaag agatttattt gggataaaac cactttatta
     2881 tataaataag gaaaatgcaa taattttttc ctcagagtat aagtttttac ttgaatatat
     2941 gaaaaattta aatataaatg aaagaagctt acaaagttat ttttcatttc aatatgtact
     3001 tcctgaagat actatgatac aaggaataag gctgatacca gcaggtcact attttagggt
     3061 agaaaatggt atactatctt taaagagata taataaactt gagtttagaa gtagtacaaa
     3121 atttttttat actaaaaatc acttaggcaa tagagatgtg aacgaggatg atataagaaa
     3181 tatagtagta gattcaatag taactcatat ggaagaggag aaagaaattg gaacattttt
     3241 gtctggtgga atagattcat ctattataac tactgtggct tcacaaatta atccaaatat
     3301 aaaatctttt tctgcaggct ttagtgtcaa aggatatagt gaattagaag tagcaaagaa
     3361 aacagctgat aagttaggta tagaaaatat ccagattaat ataacacaag atgaatatat
     3421 aaaatcatta ccgaatgtaa tttattcttt ggatgaccct atagcagacc cttcagaagt
     3481 aggtctttat ttcttaatta aagaggcagg taaacatgtt aaagtagcat tgtctggaga
     3541 aggagcagat gaattatttg gaggatataa tatatataaa gagtatagta ctatgaaatc
     3601 agttgtcaat tcacctactt atattaaaag tatattagga agagtttcag aacttatgcc
     3661 aaacataaaa ggaagaaatt atctttatag agctacaaca ccattagaaa aaagatatat
     3721 aggaaatgca aaagtttttg aaaacagcga agtaaaaaga ttctttttta agtataagga
     3781 aaagaatata tatgaatacc tgttgtctaa tttgtataga gatgcacaaa aaaataatta
     3841 cgattatata agtaaaatgc aacatataga tgtgaataca tggcttcaag gcgatatact
     3901 tcaaaaaatt agcaaacttt ctacagctga gcaggttgaa cttagagtac catttttata
     3961 taaagatgta tttgatgtag caaaaaattt aagaatggag caaaaaataa ataagaataa
     4021 tacaaaagtt ttacttagag aggcgtttag agaaatagtc ccagaacatg ttgttcaaag
     4081 gaaaaaatta ggatttccaa ctccaataag agtttggtta aaagattctc taggggatat
     4141 tgtaaaggaa actatttata attcaaatgt agatgaattt atagataaaa aatatgcaat
     4201 aaaactttta gatacgcatc ttaaaggtca tagagataat tcgagaaaaa tatggactat
     4261 atttacattt tgtctatggc atcaattatt tattgagcat aaaaatgtcg agtattaata
     4321 ctgttttcaa tattaatcag agggcaaaag catgcaatgt tttcaccctc ctgattatta
     4381 tggaatagga taagtagaat tttgattgat tagtttacta tctcaataaa attattggca
     4441 aatattttga caagactact ttcaacagct aaatttaagt tttgtccatc atcatatcca
     4501 gcggaaatca atcctagcaa gtttccaaac atatccaaaa gagctcctcc tgaactacca
     4561 ctagagattg gagctgtaaa ttgtatcatt tgaaccgttt caaaatcacg aaaagctgag
     4621 ataattccat ctgaaactgt attaaaaaga cctaaagggc ttccaattgc aactattttt
     4681 tgacctctca caggtttttt actgacttta acaggtattg gcttgcattt tctattaacc
     4741 tttatcacag ctaaatcata atctgaatgg tattttataa tttggtaaga tgtataaact
     4801 ttatcatcat tttcaaatct aactaaaaat gaatacccat cattgactac atgaagattc
     4861 gtaagtatat aaccttcatt atttattact actccagaac cgctcttaaa cggtttattt
     4921 tcgttattgc acacaacaat cataacaaca gaagctgata actttgcaag gtcttcataa
     4981 gaaagttcta cttcctcatc ttgtacaatt tttttagatg ttagatttgt gttattaagt
     5041 gtatttttag agttaggttt attcgtagta ggagaagtct tattggtatt ttcactgtaa
     5101 tttatatttg taatatgcct ttcaaaaggt atttctaata tatttggagt cttcctagaa
     5161 agttcaaata gagtagaaaa ttttgaacat tcaggatata aatcaagaat atctttattt
     5221 ggatttatat ataaaatatc acacccaagt tgtgataaaa aatataagaa aaaaagttct
     5281 tgccttttaa tatttccaaa gtatactatc tttggtgaaa tagtagtctt caccttgtta
     5341 taaaataatt taggtagaaa atagtctatc caacacaaaa gtttaactgc aaagtttttg
     5401 atgatagagg atgtacaatt tggcatactt gtggaaaata aatctaaagt atttttaaat
     5461 gcaatctttt tagtccaatt taaagtgtca ttttctattt tacatggaaa gtcgatatta
     5521 tataaatccc aactgttaaa cttagaacta tcataaatat taaaaatttt aagcatctta
     5581 tctgtttgtt ctttgtcaaa atttattttt agattgttta atctaatata gggaattgta
     5641 ggattattaa aaaaataagt atctatattt ttaatttttt ctatgtattt atcaattgaa
     5701 tcatcaacac ctatatatct tgtaaagtag acttctttaa tatatgaaga actcttattt
     5761 ttataggtag tatcagatat aaattcaatt agaggttcag tagacttttt tattgaaatc
     5821 tttaatggtt taatagtaca aatcatattt tttctcctat aataagatga tataatctat
     5881 tataaaacaa cttaaaacaa tatagtacaa taattttgta gtttcaaaat aaaatatgta
     5941 cttgtttata taaatgatat ataattacat attaaacata gcttttatgc atttaataaa
     6001 gtatgtaaaa tctatgtaaa aagtaagaaa tataaacatt tttttaatta tattttaaaa
     6061 atatcaagca agttttcttc acaaatgaat aaaaaatgtt ataatatgat taaagaaaaa
     6121 gataaataat tagcaagatt tgtttagcta aaattaacaa gggagcgata aattatgggt
     6181 ataacattat caaaaggcca aaaggttgat ttaactaaag gaaatccagg ccttaaaaat
     6241 attttagtag gtttaggatg ggatactaac aagtatgatg gtggatttga ctttgattta
     6301 gatacagcag catttttaac aggagcaagt ggaagtgtta ctaatgatgg agattttgta
     6361 ttttacaaca atttaaaaca tacatctgga gcagttgagc atctaggaga taacagaact
     6421 ggcgaaggtg atggagatga tgaacaaata gttgttgatt tatctaagat tcctggagaa
     6481 ataagcaaga tttcttttac tgttacaatt catgatgcaa cagaaagaag acaaaatttt
     6541 ggacaagtaa gtaattctta tataagaata gtagataaag acacaaatga agagttaata
     6601 aagtatgaat taggagaaga ttttagtata gaaacagcta tagtagtagc tgaaatatat
     6661 aagcacaatg gagaatggaa gtttaatgca ctaggttctg gctttgaagg tggtcttgct
     6721 gcattatgtg gaaactttgg aataaactta taatttcaac tataacaata aactaaaggg
     6781 ggatattttc catggctata gtattaaaaa aaggacaaaa aatcgattta actaagggaa
     6841 atccaggtct taaaaatata aaacttggac taggatggga tacaaattca tttgatagtg
     6901 gctatgatta tgatttagat gtaagtgttt tcatggttgg agaatctcaa agagttgaaa
     6961 aagatgaaga ttttatattc tacaataact taaaacatcc atctggagca gttgaacact
     7021 taggtgataa tagaactggt gaaggtgatg gagatgatga ggaaatatta gtgaatttag
     7081 agacaatgcc aaagcatata caaaagatag ctgtaacagt tacaatatat gaggctgctg
     7141 aaagaagaca aaattttgga caagtaagta actcatatat aagagtatta aattctgaaa
     7201 atgatgaaga aatattaaga tatgacttag gtgaagaatt tagtatagaa actgcaatta
     7261 cagtatgtga gatatataag tataatggag aatggaagtt tagtgcagtt ggagcaggat
     7321 ttgaaggtgg cttagaagca ctttgtagaa actatggctt aaatgtttaa tttaagcaat
     7381 ataatatatt aaatataaat aacctataca aataatgtat aggttatatt atataaaatt
     7441 ttgtggaggt ttagtatgtc gattaattta tcaaaaggtg ataaaataga tttaaaaaaa
     7501 tctaacccag gactgagtaa catacttgta ggtctaggat gggaccctgt gcaacaatct
     7561 ggcggaggtt tttttaaatc gttatttggt ggaggacaag ctgatataga ttgtgatgca
     7621 tctgtattta tgcttaatca agaaggtaaa ttaagtggaa taaaagattt aatttatttt
     7681 ggaaatctaa aaagtgcctg taaatcagtt ttgcatacag gagacaatct aactggtgag
     7741 ggtacaggtg atgatgaaca aatcctagtt aatttggata aagttccatc aaatattcat
     7801 aaattattgt ttgtagtaaa tatatacaat tgtgtagata gaaaacaaca ctttggaatg
     7861 atagaaaatg cctatataag agttgaagac caaggtaata agaaagagat agcaaaatac
     7921 aatctatctg ataattattc tgaaaaaact actcttatag taggagctat atatagaaaa
     7981 gatggaagtt ggcaatttaa agcaattggt gaaggaacaa aagatgcggg tcttaaagaa
     8041 gtaatgcaaa atttagacag gattgagtgt gcatatggaa tttaataatg atatcaaata
     8101 ttataatgta gataaagaag aagttacaaa agacttatct gttaatcctg aaaaaggttt
     8161 atcagaatca gaagtcaaga ctagaagaga aaaatatggt ttgaatgaat ttactccaaa
     8221 agaagagggt agtttttggg atgatttaaa ggaaagttta agtgaaccaa tgatagttat
     8281 cttgattatt gcagcagtag taagtgcagt aattggggaa actcatgatg caatagggat
     8341 tgtaggtgct atagcaatag gtatagcaat aggtatgatt acagaaggtc gttctaagaa
     8401 agcagcagag gctctttcta agttgactga aaacatagaa gtaaaagtat tgagagatgg
     8461 ggaagtacat caaatttcta agagtgaatt ggtaccaggt gatatagtat atattgaaac
     8521 tggtgacatg gtacctgctg atggtagact tatagaaagt ataaacctta aaattagaga
     8581 agatatgtta acaggagaat ctgatgacgt atctaaaaag tgtgatgtag tagtttctat
     8641 ggaagagata gaatctaaag gagcagtagt agtacaggag ccaatacctg caaaacagat
     8701 aaatatggtg tttggtggca cacttgtagc ttatggtaga ggagctctag ttgtaacttc
     8761 aattggagat aatagtgaaa tgggtaaaat tgctcaaaac ttatcagaaa cagatgagca
     8821 aactccactt cagataaaac ttggaaattt aggtggtttg atagccaaag tttctagtgc
     8881 agtagcagga ttactattta tatttatggt tttccaaatg ataagtaaga atgtattaaa
     8941 tgtagatatg tctggaatat taccgttttt agaatcaata gacccagtta aaacagcatt
     9001 tacagtatgt gttgcgttga tagttgcagc agtgccagaa ggtcttccaa ctatgataaa
     9061 tatgacactt gcaataacaa tgcaaaaaat ggctaaaata aatgcattgg ttactaaaaa
     9121 agaagcttgt gaaacgatag gttctgtttc tgtaatatgt tcagataaaa ctggtacatt
     9181 aactgaaaat agaatgactg tagaagttgc atatgttgat ggcagatata ttgaaagttc
     9241 agaagaggaa ataaatagtt attttgaaga aaactgtatg ataaactcta cagctgatgt
     9301 agagcacaat gatggtgata ttaagtattt aggaagtgct actgaatgtg cattgctttt
     9361 atattacaaa aacgtagatt atagacaagt tagaaaaaat tctaatatag tagctcaaaa
     9421 tccttttact tcagattcaa agagaatgac ttctgttata ggtcaagata atcatcatgt
     9481 actattatca aaaggagcac cagaagtctt acttgaatta tgttcacata ttcaaagagg
     9541 aaaagacata gttccattaa ctgaaaatat aaaacatgag attttagaag aaataaagaa
     9601 attgcaaata aaatcaatga gaactttagg gtttgcatat aaagaaatct cacaagctga
     9661 agaagaagca gcagtaactg ctgaaagtga tgctatgaat gtaagtgcaa tggaaaacaa
     9721 tttagtattt agtggttttg ttggtataag agacccactt agaaaagatg ttatagagtc
     9781 tgtaaataca gcaaataaag ctggtgtttc tgtaaaaatg cttacaggag ataatataaa
     9841 tacggcaaga gctataggtg aagagttagg cctattaaaa aataatatga gagtggttga
     9901 agcttcatat atagatactt tagatgatga agaattaaaa caagagatac aaagtatttc
     9961 aatcgtggca agaagtaaac cagatagtaa aatgagaata gtttcagctc tgcaaaagag
    10021 cggagatgtt gttgcagtaa caggtgatgg tataaatgat gctccagcac tttcaaaagc
    10081 agatgttggt atagcaatgg gtatatctgg tacagaggta tctaaaaacg cagcagacat
    10141 aattttaact gatgatagtt ttagtaccat tgtaaaaggt attaaatggg gtagaggaat
    10201 ttatgataac ttccaaagat tcgttcaatt ccaattaact gtaaatgtaa ttgcattttt
    10261 agtggctata atatctcaag ttatgggaca agagatgcca tttactacaa tacaattatt
    10321 atgggtaaac atcattatgg atggaccacc agcactagca ttaggtttag agccagttag
    10381 ggaccatgtg ttaaatagaa aacctgttga tagaaaagcc aatataattt ctaagtcaat
    10441 ggtgtataca atagtattaa atgcatttta tataacagca atactaatgt tacaatctac
    10501 atttaatttc ttaggagttg atgaagcgca taagggaaca gtaatgtttg cgttatttgc
    10561 ttttagtgca ctgtttaatg catttaactg tagagagttt aatgcagata gtatcttccc
    10621 taattttaca cataacaaat tagcactaca aataatagtg ttgacaggaa ttgcacaagt
    10681 aatatttact cagctattcc aagatttctt taactctgta gcaatggatt ttatgacatg
    10741 ggtaaaagtt ttatgtgtag cagcaagtgt aattgtggtt aatgaagttg taaaatgtat
    10801 aataagactg gtaaaaccaa aaaagactgc ttaaaacaaa ttttttagaa gaaaacagac
    10861 tgactcaaaa tatgaatttt gggtcagttc tgaataaaca tttaaattgg gaggatagtt
    10921 atgggtgact caaaggtatt tgaaaaaata ttctccagcc aatcagatag aggaaattac
    10981 actccttcaa agggatatct aagttatttt atttcgtata ttggtttaga agatgaagtt
    11041 ttgtacaatc tcgagatatt taagacaaaa caaaatattg atagcaaaaa agatattgct
    11101 ttatttactg atgttatagc aaatcctagt gattttgata ttataaatta ttttaaaagt
    11161 ggacttcaaa aatatagaac tagcatggaa gatgtagata taaatatttt gggatttgaa
    11221 gagattgatt ataaaataaa gcaagcaatg gatagagtgt taaaagaaga ggaaaaagaa
    11281 tttactaatg atagagttaa acaaaatttt atagtgaaaa taatggcatg gataaaaatt
    11341 tatatcggtg ctttagatat aaataaaaat gaagctccaa aagtaatatt ttatggagat
    11401 ataaaaaaac atgaagttta tttactctta atattatact tggcaggttt tgatgtttta
    11461 tatcttaatc caaattcaaa gagtaatata gatattttaa aatcagaaag atacaatata
    11521 gagtttgaag aagccaacat aatagaagaa aaaatttctt ttgaagaaag ggttatttta
    11581 ggggaaaaaa tagataaaag ttctgtaaaa aaagctttta ctgttggggc agaagcatca
    11641 aagcgtataa gtgaggaatt gttaaatgat gcaggattta taaaaccttg gcaactccaa
    11701 gatagaaaaa taaaaaatct acttctaagt tcaactgttg atgaaatatc aatatactgg
    11761 aatcaaccac ttaaattaag accaggattt aagtttaatg atgctattgt agaagctcca
    11821 aattttcttt ctaagattaa tggaatatat aacgataaga atgaatatat taagttttta
    11881 gatttattaa gagattcgga aagttcaaca tttattgaat ttaatggaga tgtagataga
    11941 ttttcaaaag cttttacaag agaagctttt agtttatcct ttttattgga ttcaaaaggt
    12001 gcaatagata aaaactctgt tttaaataat aaagattatt ccatatcaac actagcattg
    12061 aatcaacaaa ttatgatttt agagaaagtg gaagagttgt tagaaggaag tatgtttttg
    12121 aatggtttaa gtggagaaga caagataaaa ggtctattta cagtacttca catggataag
    12181 aaatttgttc atatgatgaa caatttcgat tactcactta taaacccaaa attgattata
    12241 tacatgtaca agagtattgt atttgataaa gaaatagttt ttcttatgct tttacttagt
    12301 aagattggat ttgatattat catattatgt ccaggaggag aaaacaatat agagaatgtt
    12361 ataaataacc aattgattga tgtacacaga ttggataaaa tggtatatga ccttaaatta
    12421 aattcgcttg aaaatgatat acctttactt aaaaaaattt ttggaaagag gagacgattt
    12481 tagatgggga taaatataaa tagtttttca aaagataaga actctgtaga ggttactgag
    12541 aatttgccta cagcagttca agaagaaaac ttcgatataa tggaatatac aaataataaa
    12601 aaaaatgaac tgagaaagtc taaggaagtt gaggcattga catcccttat agaagtagaa
    12661 aatccagata cgattttaca gtttggtagg aaagcatctg aaggagtagc aagagtttct
    12721 gatagccttt taaatacaat aaaattaaat agaaatgaag aaaattctaa aatgctggtt
    12781 catttaacta aaataatgga caagtttgat ttagacgatt ttcaagaaac taaggaacca
    12841 aatttcgttc aaaaactttt caaaaaagct aataatgcca ttgaaatgat gtttcaaaag
    12901 tatgaaacat tgggaggaga agttgagaaa attcaaattg aacttgaaca atacgaaaga
    12961 gatatagcac tttctaataa gcaaataggt gctatgttaa atgaaaactt tgagttttac
    13021 aatgaacttc aaaaatacat tgttgctgga gaaatggcaa tagaagaaat ggataatgaa
    13081 atactacctt tctttaaaca aaaatcagag actagtggag accaaatgga tgttgtcaat
    13141 tatcaagaac tattaaaagt ttatgatatg ttaaatcaaa gagtctatga tttaaggata
    13201 gcagaaaata tagctatcca aacaatacct atgcttagag gtatgcaaca taataattat
    13261 ggtttaatta gaaaaataaa tagtgcattt gtcgtaactt taccagtatt taaacaatgt
    13321 ttatctcaag ctatattact taaaaagcaa gaattacaag caaaatctct aaaagcactt
    13381 gatgacaaaa ctaatgaatt attgcttaga aatgcacaaa atgtaagtac tcaaagtgca
    13441 caaatagcta gaatggctgg aacaagttct gttcaaatag aaacattgga aaaaatgtac
    13501 aatactatca aatctggtat agatgaaact atgagaatag aagaaaacaa tagagcttta
    13561 attaaggata atacaaagag attggaagaa ttaaatacga ctataattta taataagtag
    13621 tattatatta agggctaatt tgtataaagt tggccctttc tatgtatatg aggaggctag
    13681 acattgaaat atttcgatta tatctgcaaa gatgatttgg agaaaatttt tttgaaggag
    13741 ccagaagatt ttagtgctaa gactgaaaaa gatgtgttga aatatgcact gggcgctttt
    13801 ttatacgttc cagctactca atataatatg atttataaga gtattatagg ggatgttaag
    13861 ggagttagac cattagctat ttgtttagaa gatgctgttg gagtaaatgg agagttggag
    13921 gctatagaaa atcttagatt aattttaaaa aatattagca atgaaagtat aactaataaa
    13981 gatggaatac cactaatttt tgtaagaata aaagatgtgg agcaactgtt gagaattaaa
    14041 gagattataa ttaaaaatag acattctata acaggaatat taattcctaa agcaaattcg
    14101 gagttaatag aaaattgtat agaagcttta gattctatga atcttcaaga tatgtatgtt
    14161 attccgataa tagagacaaa agaatttata tataatgaaa aaaaagaact tagttttact
    14221 aatttgtaca atgctatttt aagacataag tcaagaatat taagcattag agtaggcata
    14281 actgatatat tagggatgta tggtataagg agagataaga acttctctat atataataat
    14341 ttgatttgtt cttcatttat attagatata atcacatatc ttcaaagacc agagttagat
    14401 atacctataa gtggtggagt atcagaattt tttgatatga cgaataagga tataagaaat
    14461 aagtatatag aagaaatatt attggataaa tatcatggat taattggaaa gaccgtaatt
    14521 catccaatgc aaattcaaat tgtacaagcg ctatctacag tatcatatga agattttact
    14581 gatgctttgg atatactgga tagtacagac agtaagtatg gtgtgagcaa gggtgtatta
    14641 ggagagagaa tgaatgaaac aaatccacat tttttatggg ctaaaaaaac attgattcta
    14701 tctaaaatat atggtgtatt aaataaagga gtagactatg aagaattgct taaattttaa
    14761 ttgtgagatt gacattattg ataatccatt gaatttagaa ctaaatgatt ttttagacgt
    14821 aggaataaga aataatagca aaagacgttt tttgtttatc tcaaagaaac tcggtaaaca
    14881 tttagcatgt aagccaagtg agatggataa tttgggaaaa ttaatggcta caatttataa
    14941 tgaaaaaaat aaggaagaat caaatggtac tgttatagct tttgctgaaa ctggtacagc
    15001 tgttgggcat agtttttttg attacttatg tggagattat gaatttattc atactactag
    15061 agagcagttt gacgagttag aaaatctgga atttttagag gaacattccc atgcaacaga
    15121 ccagaattta tactttggta tgcttaacaa ctttaaattt ggagatgaga taatattggt
    15181 tgatgatgag attaccacag ccaatacatg catgaatata attaggaaaa ttcaaagcat
    15241 ttatcctaaa aagaaataca ctatatgctc aatactcaat tgggtaagtg atgaaaattt
    15301 aagtaaagtt actcgtttag aaagagagct agattgtaag atagattttg tatacttatt
    15361 taaaggaaac tttaaatttt atatagatga agatattatt tcaaattaca acgataatta
    15421 tagtattact aaattagaga ctatttcaag tgataaagta aatttagtag taaatcatat
    15481 ttatgttgat ttagaagatt atattggaaa taagaaatat gtaaaatata caggaagatt
    15541 tggaattaat agaagagaac aatttagatt aaaagaaatc gttaagagag aaagtaaaaa
    15601 aataactatg gccagtaaag aatctttaaa aaatgaaaaa gaaaagattc tatttttagg
    15661 tactgaagaa tttatgtata tacctatgct gtttgcaaaa gaaaaagaaa atcaatatga
    15721 tatatactat cattcaacaa caagaagtcc aattattaat attgataaga ataattatcc
    15781 tattaaaagt aaatttatgc taaagagttt ttataatata gatattcaaa attatattta
    15841 caatatagat aaacataatt tttctaagtg ttatttattt gtagagctga ataaaagtga
    15901 aaattcttat ctagaattta ttgatataat taaaaaaaca agtataaaag aattaactat
    15961 agtatgttgt agctaaagtg ttttaacagg ataaaatata tcacgatttt aagataggag
    16021 ttgagtcata tgagagattt tagcacgtat tctaaagatg atgttatttt tttattaaaa
    16081 gatatatcaa atttaattga agaagaagga aataaagaaa gagaattaaa aatacaaaat
    16141 ggtagacatt attcagaaat gataccaata gagtatgaag ttagtgaaga ttatctgaat
    16201 ttatatcatg agaaactaag agaaaataaa gataaacttg cattttctat aggagttatg
    16261 tgtgaaaaaa taattaaaaa aaatggaaat gatgtagtac tagtttcact tgctagagca
    16321 ggaacaccta ttggtatttt ggcaaaaaga tatataagaa gcaagtataa tgtaagttta
    16381 cctcactata caatctctat aataagagat aagggaatag atatgaatgc aattgaatat
    16441 atagtaaaga atcatccgag ctcaaaaatt caatttttag atggatggac tggtaaagga
    16501 actatatcaa aagaacttga aaaagcatgt gatgaactta atgttaaatt taaaaaatat
    16561 tttgactcaa cacttgctgt attagctgac cctgctggat attcaggact ttatggaatt
    16621 agagaagatt tcttaatacc aagtgcatgt ttaaattcaa cagtttctgg tttagtaagt
    16681 agaactgtac taagagagga tttaattagt aaaaatgact ttcatggagc taagttttat
    16741 agacatttaa aagataaaga tgaatctatg aactatatcg aaactataga agaatgtttt
    16801 aaaaatcaat ttaagaatat atctgatgaa gttgaaaact gggaaagtga cattataaca
    16861 agagatggat actttgatgt tttaaatata aaagaaaagt ataacataac agatattaac
    16921 tttatcaaac caggtgtagg ggaaacgact agggttttac ttagaagagt tccgtataag
    16981 attcttgtta aagacttaaa tgataaatct ttagaccata tattcatatt agctaaggag
    17041 aaaaatgttg aagttgaaca aatggattta aaagcctata aatgttgtgg aataataaaa
    17101 aatatgaaag atatttagga aatatattag acaggagaat attgaatgat tgttttttca
    17161 gatttagaca ggagtatcat ttactccaat aaatttttaa atgctgatag taaatatgct
    17221 aatatagaaa tttataggga aaaagaaata tcttatatat ctttagatac tataaattta
    17281 ataaagcaaa tacaatatta tggtatgttt atacctacaa ctactagaac agtggagcaa
    17341 tttaagcgta tagaatttaa taaatatggg atttattttc cttggagtat aacttcaaat
    17401 ggaggagtta tacttaaaga taatgaaata ttgaaatcat ggagtgaaaa aatagataaa
    17461 ctaaaatctg attatgagcc cattgaaagt atgattcata aatttaaaga ctatttgaat
    17521 gtagatggaa taactaattt taaagttgca gaagatacat ttttttatat agttgttgat
    17581 ttatcaagat ttaatttgga ttcaatcaaa gaatatacaa atatattgga atcaaaaaat
    17641 tggaagtttt atgtgagtgg cagaaaaata tattttatac caaaagaaat ttcaaaagaa
    17701 aatgctataa aatacttgac taaagaatta ggaatagaat atttttatgc agttggagat
    17761 tctattatgg actatggtat gcttaatatc tcaaataaat cctatgtatt gaagcatggt
    17821 gatataaata aaaatgaaat agaaaattca tttatatcaa gttctttcaa tggaatgagt
    17881 ggaactgaag agatactatc taacatttta gatgagaact gcctacttaa tatataatga
    17941 ctgatatata aataataaac tagaaaaatc tgaaataaat tatagtaaag tttatcatac
    18001 taatttattt cagattttta tcaatttata tttaagtaag aactcaatat gttaaaatga
    18061 aggtggagtc attgcccaga ctgagataca tacctcatca tcataatttt catacacatg
    18121 tggtatagta ctgttaaaat aaaaactatc tccttcctcc aatagatatt ccttatttcc
    18181 aagtgttatc ttcattttac cttttattat atagccacat tcttctcctt cgtgtgtcac
    18241 aaattcactg tttttgtgtg tatgaccatc tagtgtaaca agtataaatt ctattttttt
    18301 cccagataaa ttaggaacaa gaagttcgta aaattttgta gaatcattag ttactatttt
    18361 ttttcgatta tttttcttta ctactatatc agagtcttct cttccaatct cttcaaaaaa
    18421 ataacctata tttatatcaa gagcttttga tattttccac attgctacaa tagatggaac
    18481 aaccatatta cgctcaattt gacttattaa gcctgtactt aaatctgaat tttttgctaa
    18541 agtagagata cttatatttt tagattttct aagagatcta attttgcttc caacatctat
    18601 attcattaga tacaaacccc ctcagacatg attataacat ataatttata aagattaata
    18661 aaataaaaaa aaagttttac aatacaagta ttttttatgc tatattgaat tttctgaaaa
    18721 gatgcattat aatagtatta atattcaata tattgaatat tgataacgat attttaattt
    18781 aatgaaatgg aggtaattaa gatgaagagt tttgtaagtc ctgataatat ttgggtatta
    18841 tgggcagttg taactggatg ggcagcattt agtatttatt tggaacaaaa gtacaattgg
    18901 gcatcaaaag tgtcgggagc aataatagct cttgtaggag caatgttatt atcaaatcta
    18961 aatattatac cagtagagtc tgttgtatat gaccaagtat ggggatatgt tgttccttta
    19021 gccatagctt tattgttata tcaatgtaac attaaaaaga tatggaaaga aagtggaaga
    19081 ttgctcatta tatttcttgt aggttctgta ggaactgtac ttggagctat gattggattt
    19141 ttagcattaa aaaatgtagt accagattta aatattgttg cagctatgat gacaggttct
    19201 tatataggtg gaaatgtaaa ctttgctgct atgtcagggg cgtttgatgc gccaggagaa
    19261 ttagtatcag caacagttgt agcagataat cttttaatgg cattatattt ctttgtctta
    19321 atagctatac catcaattgg attttttaga aaacatttta aacatccaca tgtagatgaa
    19381 atggaaagta taggtataac tgaaggagaa acagtagcag caaattattg gggaagaaaa
    19441 gaaatatctt taaaagatat agcaatagcc attggtagcg cttttataat tgtcgcagta
    19501 tctgtagaac tatcaacttg gtttaaagct ataataccat tatcaaatcc ttttttagca
    19561 atgttaaata ctttatttgg aaatcaatat ctaataataa ctactttgac tatgttgttt
    19621 gccacattta tgcctaattt ctttggtgat ataaaaggag cacaggaatt gggtacattt
    19681 ttaatatata tattctttgt tgtagtaggt gttcctgctt caataacatt aataattcaa
    19741 aaatcaccat tactactttt atactgcgga ataatggtac taataaacat gctagttaca
    19801 tttatagttg caaaaatatt taagtttagt ttagaagaag ctattcttgc atctaatgca
    19861 aatattggtg gtcctacaac agcagcagct atggcaatat caaaaggatg gtctaagcta
    19921 gtagggccaa tacttatagt tggaacattt ggatacatag tcggtaatta ttttggtctt
    19981 ttagtaggaa atattttgat ataattttac gtgaaaaaaa gttgtttttt agaaagattt
    20041 ttatttaatt ggaggttgtt atgattttcg atggacattc agatacttgg gcagatgtaa
    20101 caataagaag gcttaacggg gaaaaagatg tatttagaag aatccatctt gataatttta
    20161 aaagagcaaa tatagaagga gctatttttg taatatggat agacccacca tatgataaag
    20221 agcctgaaaa aagagttaaa caaattataa gctctataaa agatgaaatt gaagatatga
    20281 aagatgttgt aaacatagta aaaaaatatt cagatataga taaaggtata agtgaaaaca
    20341 aaataaatat tttaattggt cttgaaggat taagccatat tggaagaaat atagatttac
    20401 tagattattt ttataaagaa gttggtgcaa gacatgcatc attaacttgg aatgaacaga
    20461 atgaacttgc tacaggatgt ttaggggatg aaaatcgtgg tttaactgaa ataggtaaaa
    20521 aagcagtcaa taaaatggaa aaattgggca tgatagtaga tgtgtcacat ttaaatgaaa
    20581 aatcattttg ggatttaatg tctgttgcaa gtaagccagt tatagcttct cattctaatg
    20641 ctaggagttt atgtgatgct aaaagaaatc ttacagataa tcaattaaaa gaaatttcaa
    20701 atacaggtgg attagttgga ataaatagtt ttagaggatt tactaatagt aatcctaaga
    20761 agcaagattt aatacatttg gttgaccata tagactatat ggtaaatctt ataggtatag
    20821 aacatgtatc ttttggtttt gattttagtg attacttagg gaaagagact ataggttctt
    20881 ttactggaaa tgctagtgtg ccaagtgtag atggtcttga aagcacacat acagcacaga
    20941 acatagtagt agagcttgaa aatagaggtt ataaaaagaa agatatagag ttaatctcta
    21001 gtggtaattt ttataggctc tttaaagata tactaaaata atataataaa gaacttaaat
    21061 ttataaaata gtatatttat acaaataata tctacatatt taaattggcg ttcataattt
    21121 attaaattaa attttaatgt tactagaagt ttcaattcta gtaacatttt ttatgttaaa
    21181 aacagatata gatatatatt gacaatgata attattattg ataaactata aaagtgaaaa
    21241 tgataataat tttcatttta attaataaaa gatttttaag gagggagaat gaagaaaagg
    21301 tatttagtca taggaataat aattttgtct tatttttctt tatttatagg agctgaagat
    21361 ataaatataa tgcatatatt tgccaaaaat cagcataaac ttatgatatt tatcatgagt
    21421 agaataccaa gattaataag tatattgatt gctggtgtag gaatgagcat agcaggtctt
    21481 ataatgcaac agataagtaa gaataaattt gtatcaccta caacaggtgc tacaatagat
    21541 gcagcacaat ttgggatagt aatatgtatg cttttagtac caactgcctc tatttttaca
    21601 aagacaataa tagcatttgt attttctctt gtagggactt ttacgtttat gaaaataata
    21661 gggaagttac aatttaaaaa tataatcttt gtaccattag taggtataat gtttggaaat
    21721 ataataggtt ctatgacgga ttttatcgcg tataaatacg atttgagtca aaatgttagt
    21781 tcttggatgc aaggtgactt ttctatgata cttaaaggaa attatgagat attatatatc
    21841 acaatacccc ttataatatt agcatatatt tatgcaaata aatttactgt tgttggtatg
    21901 ggtatggatt ttgcgacaaa cttaggtctt agttacaaaa gaattgtcaa tataggtctg
    21961 ataatagtag cacttgttac agtatgtgta gtcgttacag ctggtaatat cccttttata
    22021 ggtctaatag ttcccaatat cgtatccttg tatatgggtg ataatataag agcaagcata
    22081 tggtatactg gtttacttgg agcgatattt gtacttatat gtgatatttt tggaagaatt
    22141 attatttatc catatgaaat atctataggg cttacagttg gagttatagg aagtatacta
    22201 ttcctttatt taatattaag gaggaatgta aatgaagctt agtctcaatc aaaaaattta
    22261 ctttgtaagt atattactat tcatatcaat agcacttttt ataatttatg gaatagacat
    22321 gaatcattta gaatatgcat tatcacaaag aataccaaaa atatttgcta tggtattagg
    22381 tggaggatgt atagcattta ctactgtagt gtttcaaaca attacaaaca atcaaatatt
    22441 aacaccaagt gtactaggtt tagattcatt gtatgtaatg attcaaacta taatagtatt
    22501 catatttggt tcaagcagta gtctgattat aaatgaaaat tataatttta ttattaatgt
    22561 agctatgatg attggagctt cattgttatt atataagacg ttatttgaaa aaaataaaaa
    22621 taatattttc tttttaatcc tagtaggaat gatatttgga accttattta aaagtgcaac
    22681 aacatttatt caggtaatga tagaccctaa tgaattttta gctttacaaa ctagtataat
    22741 ggcaagttta aacaatataa acactaatgt attgttaata gcatttataa taattattgc
    22801 cataatacct tttatatatg atgaaataaa gtatttagat gtattgtcgt taggtaaaga
    22861 acaagcaatt aatttaggtg tagattttga taaagcagtt aaaaaaatga taatattaat
    22921 agcaatttta gtctcaatat caacagcact tattggacct atgacatttt taggactttt
    22981 acttgctaat ataacaagag aaatttttaa aacatataag catacatact tgatttcggg
    23041 ttctatgttg atagggatga ttacattgat aataggtcaa ttttttatac aacatgtatt
    23101 taagtttgat acaactttaa gtgtagtaat aaattttata ggaggaattt actttattca
    23161 attactatta aagggggcaa atagatgata gagataaaaa atatatttaa aagatataag
    23221 aataaaaatg ttgtagatga tgtctctttt agtatagaaa agggaaagat aacatctttt
    23281 ataggaccaa atggagctgg aaaaagtaca gtactatcaa tagttacaag acttatagga
    23341 ggtgatggtg gagaagtaat aatagaagga aaaagcttga ctaattatag caataaagaa
    23401 ttagcaaaaa aaatagctat tcttaaacaa tctaacaata taactttaaa gcttacaata
    23461 agagaattag ttggatttgg aagatttcca tatagtgaag gtaatctaac taaagaggat
    23521 gaaaattata ttgatgaagc aatagaatat atgaagttga ctgatataca acataagtat
    23581 ttagatgaat tgagtggagg tcaaagacaa agagcttata tagcaatggt aatagctcaa
    23641 gatacagagt acatattact tgatgaacca ctgaacaatt tggatatgaa ccattccgta
    23701 cagatgatga aggtacttag aagtctttgt gatgagttag ataagactat agtattagta
    23761 atgcatgata taaattttgc atcatgttat tcagataata tagttgcatt aaaaaatgga
    23821 aaagttaaaa aagtaggtcg tacagatgag atagtaaatg aaaaagtttt agaagatatt
    23881 tatgagatga attttaacat taagaatata aatggaaatc gaatctgtat ttatttttaa
    23941 aatattgtat atgaaaataa acttgctata tgatttttta taaagttttt aaattaaaat
    24001 aaagattaat aggagagagg aaaatattga tatgaataaa aaagcagcaa tagtagcagc
    24061 agtagctatt ataggattag tgacagtgtt tgcattaggt ggaagtaaaa agaatgaatc
    24121 aaaaacatca gaaaattcaa ataatactat gaagataact cataacttgg gagaaacaga
    24181 tgtaaaatta aatcctaaaa aagtagtggt atttgattat tcggctttag atacaatgga
    24241 tgcattaggt gtagctgaga atttagtagg acttccaaaa gcgagtttac cagcatcctt
    24301 agaaaaatat aaggatgaca agtatgcaga tttaggagga ttaaaagaac cagatttaga
    24361 gggtataaag tcggcaaatc cagatttaat tataataaat ggaagacaag aagattttta
    24421 tgagcaattg tcaaaaatag caccaacaat aagtacaagt aaagatgata agaagtactt
    24481 agaatctgtt aaaaataata tagacaaaat agcaaaaata tttggagtag aagaaaaagc
    24541 aaatcaagaa tttagtaaaa ttgaaaagaa aatagaaact ttgaataaaa aagtaacaga
    24601 taaaaattta aatgctttaa ctataatggt aaatgaaggt aatttaagtg tatttggtga
    24661 agaatcaaga tttagtatat tatacaatag ttttggattt gaaaataaag ataaaaatat
    24721 aaaagaatca agtcatggac aaaatattac ttttgaatat atagctaaac aaaatccaga
    24781 agttatgttc gttatagata gaggaatagc tactggcagt gatgtaaaag aaagctcaac
    24841 tgcaaaatct gttttgaaca atgatataat aaaatctatg gatgcatata agaatgataa
    24901 tataatatat ttagattcac caacatggta tgtaaatgat ggtggtctaa catctttaaa
    24961 taaaatgata gatgatgctt caaaagcggt aaattaataa tccgatataa tcaaaatata
    25021 tttttta
//
LOCUS       DAGQVA010000055        25001 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.055, whole genome shotgun sequence.
ACCESSION   DAGQVA010000055 DAGQVA010000000
VERSION     DAGQVA010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25001
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.055"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..826
                     /locus_tag="MIV85_002546"
     CDS             <1..826
                     /locus_tag="MIV85_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBY2961876.1"
                     /translation="IYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIK
                     LKYSYEVETPAFFNSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVY
                     WFNPFIYIMDKHIDLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAG
                     LHKQSDIKKRVMNMFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDL
                     RTVSSIRFSVIGFTYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND"
     gene            1742..2764
                     /locus_tag="MIV85_002547"
     CDS             1742..2764
                     /locus_tag="MIV85_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBY2961877.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            3061..3981
                     /gene="pyrB"
                     /locus_tag="MIV85_002548"
     CDS             3061..3981
                     /gene="pyrB"
                     /locus_tag="MIV85_002548"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBY2961878.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            4020..4712
                     /locus_tag="MIV85_002549"
     CDS             4020..4712
                     /locus_tag="MIV85_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBY2961879.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            4705..5607
                     /locus_tag="MIV85_002550"
     CDS             4705..5607
                     /locus_tag="MIV85_002550"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBY2961880.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            5692..6276
                     /locus_tag="MIV85_002551"
     CDS             5692..6276
                     /locus_tag="MIV85_002551"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBY2961881.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            6491..7417
                     /locus_tag="MIV85_002552"
     CDS             6491..7417
                     /locus_tag="MIV85_002552"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBY2961882.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(7469..8359)
                     /locus_tag="MIV85_002553"
     CDS             complement(7469..8359)
                     /locus_tag="MIV85_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2961883.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            8547..9578
                     /locus_tag="MIV85_002554"
     CDS             8547..9578
                     /locus_tag="MIV85_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBY2961884.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
     gene            9872..10747
                     /locus_tag="MIV85_002555"
     CDS             9872..10747
                     /locus_tag="MIV85_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HBY2961885.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            10765..12255
                     /gene="cls"
                     /locus_tag="MIV85_002556"
     CDS             10765..12255
                     /gene="cls"
                     /locus_tag="MIV85_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBY2961886.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            12448..12732
                     /locus_tag="MIV85_002557"
     CDS             12448..12732
                     /locus_tag="MIV85_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBY2961887.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            12765..14393
                     /gene="groL"
                     /locus_tag="MIV85_002558"
     CDS             12765..14393
                     /gene="groL"
                     /locus_tag="MIV85_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBY2961888.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDVGMPGMGGGMPGMM"
     gene            14655..15395
                     /gene="larB"
                     /locus_tag="MIV85_002559"
     CDS             14655..15395
                     /gene="larB"
                     /locus_tag="MIV85_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBY2961889.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            15479..16213
                     /gene="larC"
                     /locus_tag="MIV85_002560"
     CDS             15479..16213
                     /gene="larC"
                     /locus_tag="MIV85_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBY2961890.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            16243..16662
                     /locus_tag="MIV85_002561"
     CDS             16243..16662
                     /locus_tag="MIV85_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBY2961891.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      16722..16823
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            17044..18579
                     /gene="guaA"
                     /locus_tag="MIV85_002562"
     CDS             17044..18579
                     /gene="guaA"
                     /locus_tag="MIV85_002562"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBY2961892.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(18656..19702)
                     /locus_tag="MIV85_002563"
     CDS             complement(18656..19702)
                     /locus_tag="MIV85_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBY2961893.1"
                     /translation="MPAYKDEQRKSWYASFYFTDFDGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRRWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGSIGKKNAD
                     EMNFWTLEEFKKFIEFEKKSEPRLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IRLNGEDIVSSPKTPKSKRVVPIPHFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LDRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(19779..19994)
                     /locus_tag="MIV85_002564"
     CDS             complement(19779..19994)
                     /locus_tag="MIV85_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2961894.1"
                     /translation="MLKKLRKKKRMTQLELAEKMRRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKLQEIKRRGK"
     gene            complement(20428..20829)
                     /locus_tag="MIV85_002565"
     CDS             complement(20428..20829)
                     /locus_tag="MIV85_002565"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961895.1"
                     /translation="MQTLAEIIKEYRSEHNLSLREFSNLCGVSHTYIDKIEKNRDPRN
                     GKAVEPTLDMLEKMSFGLNLTLKELLTKLGKIQPNTQQDDELLKKVNSKEDNEVNELI
                     NRLASLDSDDKNAIKKMIDNAYYKAVNTKKE"
     gene            20994..21206
                     /locus_tag="MIV85_002566"
     CDS             20994..21206
                     /locus_tag="MIV85_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961896.1"
                     /translation="MKNNLQYIRKESRISQKKFADKIGISRPYLSRIENGKVNPSLEI
                     AHKISLETGKTINEIFFDFTVNHSKL"
     gene            21446..21583
                     /locus_tag="MIV85_002567"
     CDS             21446..21583
                     /locus_tag="MIV85_002567"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961897.1"
                     /translation="MQREQTTLRIPEDLHKALIDLSSDIGMPITSIIIIACWLYISKI
                     N"
     gene            complement(21569..21880)
                     /locus_tag="MIV85_002568"
     CDS             complement(21569..21880)
                     /locus_tag="MIV85_002568"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961898.1"
                     /translation="MTTITVRIYTPLNENLEKISYQTGILKSSLILYAINDIIRNSKV
                     NELQSISYKSDDTVRSTLRIPGVLKELLEKTAKENNLSINSLINNVVHSFCISDWLIY
                     L"
     gene            22001..22171
                     /locus_tag="MIV85_002569"
     CDS             22001..22171
                     /locus_tag="MIV85_002569"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961899.1"
                     /translation="MEKVRMTVRLVPKLNQYVQNIAKECGKSKNSIIVDACWEFIEKI
                     KKENKFNVESEE"
     gene            22174..22812
                     /locus_tag="MIV85_002570"
     CDS             22174..22812
                     /locus_tag="MIV85_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961900.1"
                     /translation="MNNLQIFEKLEFGQIRMAEIDNKPYFVGKDVAKSLGYKNTNDAI
                     LRHCKGVVKHEGFKINGIKIALITEGDVYRLIVGSNLPNAEKFESWVFDEVLPSIRET
                     GQYQAQQHVITELTGTIGDLKGTIKEYKKLCKITCSKKQQYSKYIKNRLDIDKANKEY
                     NQVKARLFLILGVEKWEDIDFDTSNNLIQIIDDCIRVIKSERPYKQLSYFEN"
     gene            22871..23041
                     /locus_tag="MIV85_002571"
     CDS             22871..23041
                     /locus_tag="MIV85_002571"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961901.1"
                     /translation="MKNNISDSRVKYFCKCPYCGFDNEVEVKKGLKPKICCICTKEVE
                     YEKLEQQSTPAK"
     gene            complement(23044..23277)
                     /locus_tag="MIV85_002572"
     CDS             complement(23044..23277)
                     /locus_tag="MIV85_002572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961902.1"
                     /translation="MNIGKITKIEATCFDCGTKVTITESKFREVCDNGLPCPMCKEHI
                     SNSNFIAEQALQYNHAVNKLEKELDSCKNIHIY"
     gene            23346..23543
                     /locus_tag="MIV85_002573"
     CDS             23346..23543
                     /locus_tag="MIV85_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2961903.1"
                     /translation="MAINDNINKILRDRNLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKLADYLDVTLDELVGR"
     gene            23582..23791
                     /locus_tag="MIV85_002574"
     CDS             23582..23791
                     /locus_tag="MIV85_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961904.1"
                     /translation="MAKAVAKEQLFYRAKDIAKILDVCEATAYKIIGELNKELEKEGF
                     KTFSGRVSVAYFKERYCYKPRKGVI"
     gene            23949..24161
                     /locus_tag="MIV85_002575"
     CDS             23949..24161
                     /locus_tag="MIV85_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961905.1"
                     /translation="MVFNLEKFKVGNAIRISCERFGFEIDCIVVVATEKELNLAYFDE
                     GRGCMEYQALITEDIQDGDYEIKILS"
     gene            24260..24502
                     /locus_tag="MIV85_002576"
     CDS             24260..24502
                     /locus_tag="MIV85_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961906.1"
                     /translation="MEAARLIAMGQIKQAEKEISKLQGTKNNSSLMWWEAVKFASQNI
                     LQGLEHDIELEASTDFREFMITQEELERDRPIDVQI"
     gene            24586..>25001
                     /locus_tag="MIV85_002577"
     CDS             24586..>25001
                     /locus_tag="MIV85_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBY2961907.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNT"
BASE COUNT         9925 a         2590 c         4483 g         8003 t
ORIGIN      
        1 aatttacact atatttaaat atataaaact taaaaattta ataaatgact tatcttatga
       61 tgttgatgat agagagattg taaatcttta taaaaatata ttagaagaat ttaatataac
      121 aaaagatata aaactcaaat actcttatga agttgaaaca ccagcatttt ttaattcatg
      181 tgtacttttg ccaccacatg agtataaatt gaaagagtta gactggattt ttagacatga
      241 gcttatgcat tttaagagta gggaccttta tttaaaatat gtaatcctat ttttaaaaac
      301 agtatattgg tttaatccat ttatatatat aatggataaa catatagatt tagattgtga
      361 actttattgt gatgaaagag ttttaaaaaa tcgaaattca gaggaaaaaa aggattatgc
      421 tttaacaatt ctaaatgcaa tgagaaaagg ttcaaatact tcaaataaat ttatagctgg
      481 acttcataag caatctgata ttaaaaagag agttatgaat atgtttaatg aaaagtacaa
      541 gaatggtata ttaatggcat taactttatg tttattatct tctattactt ttttgaaggt
      601 taattcaact agtattgtta atcttaatgt attacctaaa ggatttgaag acttacgaac
      661 tgttagcagt atacgttttt cagttatagg atttacatat gcagatgctc ctaaaaatat
      721 gagggaagaa tataaaataa attgtgaatc attaggtttg atacctaaag actctgataa
      781 aatagaagtt ggtatagaat attatgacag tctattgaat gattaaataa atattatttt
      841 aacagatatt aattataaag ttttgaatag taatttgttg agaaataaat atatccttat
      901 aaaaatagat acttatatac caagaataaa aaatagtcaa gatagtacac aaggatatac
      961 ttataaagaa cttaaataag tgaaataaat tattaattat aaggtttata attttaaaaa
     1021 attagataaa ttcaggtgta aaatactata aaacacaatt cggaaaagtg tatgttgaac
     1081 ttcatttaaa atggaatttc aaagttgcta tagtaagtag tttaagcatt cttcttatat
     1141 taatctttga gaataatgta tttaaaaaag ttagtaaaaa atttaactat tgtatattaa
     1201 tgatagttgc tattgatata ttatctaaaa aaattaagta tgaaaagatt actgctagga
     1261 caatcttttc atacttaatt tttaatattt atattatcca aaattttcat ctttttaact
     1321 tagaatttga gaatcactat taggaaatag gctttgattt atgtagggtt aaaaatttca
     1381 cagaatatct aactttatac taaatccatc aaaaaatata cgccatacaa aagcgcataa
     1441 aaaaacacat aaaacaatat ttatgcgcac tttaacctcg aatggtacaa aattctttac
     1501 ttttacagac ccatattata taattaagta aataatgtat atttaggtga catattggat
     1561 aagctaattt atttatttta ttaatataat aatactataa aagttatata aagtggttta
     1621 caaaaaagtt acagatagag cttttattaa tgtattgtgt attagtattt tatccttagg
     1681 tacacttcac ctacaaaata gaatcataag ataattatgg gaaaatttta ggaggtttat
     1741 cgtgaagaaa aagatattaa taccagtatt tgcatcagtt atggcattat cagtaagttc
     1801 aattgtaaat gcagatgaag taaatgattc atctcaaaat aaggatgata aaacaaatac
     1861 tgaattaaat ttaggtgaat ataaagaagt aaaatataaa gttgcaaaaa taaaagatgg
     1921 agtagctata aagataagag aagaaggtca agttcaaaac atagcttatt ctggagatga
     1981 atttacggtt ttaggaactc aaggagaatg ggttaaggtt aaagttgaag atggcgaagg
     2041 ttggttagct actagatatg tagatatatc tgaaggtgta ggatatacta acgctgataa
     2101 agtaaactta agaaaagata agagtgaaag ttcagaagta attgaagagc tggaaaaagg
     2161 aagttcttta ttggttttgg aagataatgg agattggtta aaagttaaag atggggaaac
     2221 agaaggatat gtaaaatcat cttatatatc tgataaagct cctgtaatag aagagccaca
     2281 agtaaaccca agtattgacc aaaatgtaga ttctacaaat aataatcaac aaaacaatgc
     2341 aaatactaat caacaaaata ataattcaaa tgtgccaaca gctaactcta atgcagttca
     2401 agctgtactt aacttggcat attctaagca aggttgtcca tatgtttggg gagcagaagg
     2461 accaaacact tttgactgtt ctggatttac acaatatgtg tatagaaatg cagtaggaaa
     2521 gaatatacca agaacatcta aagcacaatc taaatatgga caaactgtaa gtaaagcaaa
     2581 tttacaacca ggagatttag tattcttcac aactaatggt tctggttctg ttagtcatgt
     2641 tggaatatat gtaggtgggg gtaatatgat acactcacca tcaacaggaa aaacagttag
     2701 tgtaactagt ataaattcat catactatac agcaagattt gttacagcaa aaagaatatt
     2761 ataatcggtt tgtaatatga caaattgata aatacataaa tatatataaa cgctctatat
     2821 tatatttaat ttaatcatgg aaacaaaata atgattatat tttaaatgta ctatagagcg
     2881 tttttgtatc actttaaatc taatcaagat tcaagttaat atgactgtta aataggagcc
     2941 ttttcatatg atgattattt gtgcaatccc ttgacaggat agggtaaagg tggtaagcta
     3001 ctaacagtac aaaaatactt ttaattttag ttcagagagg ctaaaaaagg aggacgaaag
     3061 atgttaaaat caagaaattt aatccaacca gaagactttt caatagaaga aatagatgaa
     3121 atattagaat tagctcaaaa gataattgac aatccgtcaa aatattctcg tatatgtgaa
     3181 ggaaaactat tagctacatt attttatgaa ccatcaacaa gaacaagatt aagctttgaa
     3241 tctgctatga acagattagg aggacgtgta gtaggctttt cagagccaaa ttcatcctct
     3301 gcatcaaaag gtgaaactct aggagataca atgaggatag tatctggtta tgttgatata
     3361 atagctatga gacatcctca atcaggtgca gcttcagaag cagctagata tacggaagtg
     3421 ccatttataa atgcaggaga tggcaaaaac cagcatccaa ctcaaacact tacagactta
     3481 cttactataa aatcattaaa aggaacttta gaaagccata caataggatt atgtggtgat
     3541 ttaaaatatg gaagaactgt gcattctttg gttaaggcta tggcaagata taaaaataca
     3601 aagtttgtat ttatagcacc tgaagagtta aaaatgccag attatataaa agaagctata
     3661 aagggacatg catattatga aactaataat ttggatgatg ttataggaag cttggatgtt
     3721 ttatatatga ctagagttca acaagaaaga tttgaagata aatcagagta tgaaagactt
     3781 aaaaactatt atattttaaa taaagctaaa ttagaaaagg cgtctaaaga tatgttagta
     3841 atgcatccat taccaagagt aaatgagata gacatagatg tagatagtga tgatagagct
     3901 gtatatttta aacaagctaa atatggaatg tatgttagaa tggctttaat aataaaactt
     3961 ttaggtataa atgaagacta atagttatca tataatagta aaacaaagga gattttggga
     4021 tgtataaaat tctggaaaat atatatatag gcgaagatat gtatagaatg aaagtaaaag
     4081 gtaattttga aggtaaaatg ggacaattct atatgttaag agcatgggat acttatccag
     4141 tactttcaag acctataagt atacatgata tagatgaaga agggataact tttctttata
     4201 aagtagtagg agaaggaact caaattttga gtaacctaaa ggtaaatgat actataaaat
     4261 tggaaggccc ttatggtaat ggatatgcta aggttgatgg aaaggtagct ctagtaggag
     4321 gaggaatcgg tgtagctcca ctatatttgg ttgctaaaaa tataaaaaat tgtgatgcat
     4381 atcttggctt tagagaagat gttatattag aagatgaata taaacaagta tgtaataaag
     4441 tatatacaac agtaggaaat acttttgtaa cagatataat tgatgttgag aaatatgatt
     4501 atatattaac atgtggtcca actccaatga tggaaaaatt agttaagatg gtagaaggta
     4561 ctaaaacgag aattatggta tctcttgaaa accatatggc ttgtggagta ggtgcctgtt
     4621 tagtatgtac gtgtaaaact aatggaggaa ataaaaagac ttgtaaagat ggtccagtgt
     4681 tctggggaga ggacgtgatt tttaatgggt aatttaagtg tgaaatttgg aagtgtagaa
     4741 tttaaaaatc cagtaataat ggcgtctgga acttttggat ttggaaaaga atataatgag
     4801 atttatgata tacaaaaact tggtggtata agtagcaagg gtcttacttt aaataaaaaa
     4861 cctggtaaca atggtatgag agttcatgag acaccatccg gtatgatgaa tagtgttggg
     4921 cttgaaaacc ctggagttca aggatttata gactatgaat tacctttttt tagtaaacta
     4981 gacttagtca gaatagctaa tgttggaggt gggacattag aagactactt attaggggtt
     5041 caaatgttaa atgacaagcc tatagacatt attgaattaa atatatcttg cccaaatgtc
     5101 aaagctggtg gaatggcttt tggtataaaa aatgaagtgg caagagaagt tgttcgtgag
     5161 gtaagaaaca taacgaaact gcctttagta ataaaattat cacccaatgc agaagatatt
     5221 gtaggaatgg caaaagtttg tgaagaagaa ggtgctgatg gagtttcatt agttaatact
     5281 tttaaagcaa tggcaattga tataaaaaat agaagaccag tatttgaaaa tgtatatgct
     5341 gggttatctg gaccagctat aaaacctata gctttgagaa tggtacatga agtgtgtaaa
     5401 aatgtaaata tacctgtaat gggaatgggc ggaataacta aagccacaga tgctatagag
     5461 tttataatgg caggagctac ttgtatccaa gttggaactg caaattttat gaatcctaga
     5521 ataggtattg aaataataga tggaattaat gaatttatgg atagagaagg aataaaaagt
     5581 ttagacgaaa taagaggaat tatataaggt agaataaata gtattttaaa gataaaaaat
     5641 atagattaaa taaacaataa ttttataaca ttaacatgga ggaaaaataa tatgagtaaa
     5701 gtagatgtag tggatatatt aaagaaaagt gatgcattgt tggagggaca ttttttatta
     5761 tcttcaggaa aacacagtaa tagatacgta caatgtgcaa aagtattaag atttccagaa
     5821 tatgctgctg aggtattaag tacagttgtt gaacaaataa aagacttaga tatagactta
     5881 gtagtaggac cagctatggg tggagtaata gtttcttatg agttaggaag acaattagga
     5941 aaagaagctg tatttactga gagaaaagac aatacaatgg agttaagaag aggatttgaa
     6001 gttaaaaaag gagcaaagat aataattgct gaagacgttg taactactgg taaatcaact
     6061 atggagacaa aaagagtatt agaagcctta ggtggagaag ttgtaggtgt tgcatgtata
     6121 gcagatagaa ctaatcatga tataggtatg cctatatata gtgctataaa acttgatatt
     6181 caagtttatg aatctgatga gtgtccttta tgtaaggaag gaaaattacc agttgttaag
     6241 cctggaagta gggagttcaa ggaattaggg atgtaataaa aacttaatta tttatagtgt
     6301 tacttaaaaa atgtaaattt tttagagtaa aaatttgtaa tataacatat aacttaaaaa
     6361 taaaaagcag ttagccttat aaatgaaggt tagctgtttt ttttgttaaa aatatattta
     6421 caaaataaga gatagtagca gtacaatata agtataaggt aaaagtatta tatattaggg
     6481 aggggtaagt atgaaaaatc aattaaatga aaatcataaa aaggttgtat tttttggagt
     6541 aggtgctgta ggagctactt ttgcagaaca attttttaac tctaaatatg attttaaaat
     6601 tctttgtgat aatgaaagaa agaaaagata tttagaagaa ggatttataa taaatggaaa
     6661 aaggtatgat tttgattatg taactaaaga tgagtataaa caagaggctg attttataat
     6721 tataggtcta aaatataata atttaaaaga aaatataaaa gaattagatg gattagttgg
     6781 aaaaaataca gttataatgt ctctgctaaa tggagttgat agcgaagaga taataggaga
     6841 aagatttgga attgaaaaaa tggtatattc atatgttacc aatatagatg caaagaaaat
     6901 caataataat attatacaca ctactaatgg gataattgta tttggtaaca aagataatag
     6961 tgaagataga aaaactaata taataaccga agtctttgat gatgtaaata tagaatatac
     7021 tttatcaaaa gatattcaac gagatatgtg gtggaagtac atggttaata ttggtgtaaa
     7081 tcaaacttca gctatacttg gtgcacctta tggagttttt cagagttctg agcatttaag
     7141 agaattagca aaatctgcaa tgagggaagt tgttgctata gcacaagcaa aagacatatc
     7201 tcttacagaa gatgatgtgg aacattcatt acatagaata ctagaacatt caaaagaagg
     7261 aagaacatca atgcttcaag atgtggaagc tcatagactt acagaagtag atatgttttc
     7321 taagaatatc tgcaaacttg gaaaaaaata taacatacct actcctataa atcagacttt
     7381 cttttatatg ataaaagtaa ttgaaagtag attttaaagg gtctttgtaa gaaatattga
     7441 taattattga ttttaaattt tattaatgtt atatactatt taagttacta aatattttta
     7501 actcttcaat gaaaatagtt gctgcttttg ataaagttat atcttttgga aatatatatg
     7561 agaaatgtct gttgtagctg cttccaagct ctatgacaga cagctcattg tttagaacag
     7621 gtaagcttgt cactagatta gagactattg taattcctaa attatttcta acagattctt
     7681 tgacagcata attacttcca aaaaccatca tactttttgg aataatttct ttaacactta
     7741 aaaacatatc taaataatct ctggttccag aaccatcctc cctgactatc catttttggt
     7801 tttgaagttt atcaaaacta aaatctttta ataaatgact cttgtatgga agtgctaaaa
     7861 ccatcttatc ttcaaaaaaa tattcttgaa taaatgaagg ggaagagcaa gtgccttcaa
     7921 taagaccaat gtctaaaata taatccttaa catgagaaga tacgattgat gtatttttta
     7981 taaaaacttc tacatctatg tcaggatact ttttagaaaa taatgctaga aaatttggta
     8041 aaatatactc tccaatagtt aaacttgcac caatctttaa gtgaccagtt atagcatctg
     8101 aaacttggct tacatcatga taagtaatat ttaaaagatt taatatttct ttagctcttt
     8161 tgtacaagat ttgtccactt tctgttataa aaatggtttt ttgtttaata gacctgttta
     8221 taagcacaac tttaaaataa ttttctagat tttttatgtg tttacttaca cttggttgtg
     8281 atagatttaa atattcccca gctttagtaa agtttttgta ttcaacaaca gctacaaatg
     8341 tttttaattc ttcaaacaat tttttgtctc ctttacctaa tgaaatttta cattttttat
     8401 atactttcta cagataatta tactatatat aataaccatt aaaaacatta atcattacga
     8461 tattatatat ttattttact tatggttatt acaattatat actattgcta tgaagaaaac
     8521 tatattaatt ataaggtagg tatattatgt taaagaaaaa aagcagtttg acattaaaaa
     8581 ctataaggga aatattacca ggactgtttg tatcagtatt agtaggttat attagtatat
     8641 ttatttctat tttaattcct aaggtagggg cagcatcaat ttctatattt ttaggtatgt
     8701 ttgtaggaaa cctattttta aatcaaaagg tatttcaaaa aggttataaa ttttcagaga
     8761 cagatttgtt atcatattca atagtactat taggagcaac actcagtgta tctaccttaa
     8821 tagacttaaa agtttcagga attttattta taatattgca aatgacaata acaataatag
     8881 ctgcacttta tataggtaaa aaactaggat ttgaagaaaa ctttagattt ctaatggcaa
     8941 gtggaaatgc agtatgtggt tcttctgcaa taggagcaac agttccagtg gttaatgcga
     9001 cagataaaga aaagggaatt gcagtaacta ttgtaaatgt tactggtata tttcttatgt
     9061 ttttacttcc aataatatct caatttttat atagccatga acttgtaaaa acttcagcaa
     9121 tgataggtgg aactttgcaa tcaattggtc aggttgtagc aagtggagca attgttggag
     9181 aaaatgtaaa agatttagct actattttta agatagtaag agtaatattt ctagttgttg
     9241 ttgtattagt atttggacat atgaaaaatc aatctaatag ggaaattctt gaagaagaaa
     9301 aggatgagat aaaaaagaaa aaagtgacta taccatggta tgtaattgga ttctttataa
     9361 cttgtgcact tttttcaatg aacattatac cacaagaagt atctgtgttg tgcaaagaaa
     9421 taagtaacaa actagaaata atagctttag cagcaattgg attaaaggtt aatgtaaaag
     9481 atttagtgaa acaagggaaa gaagtttctt tatatggttt atttgtaggt atagtacaag
     9541 ttgtatcagc tgtagtttta ataaaaatat ttatatagca taaaaatagt atttgtaata
     9601 ttaatttgat taattaaaat aatatgatac taataattta taatataaat aaaaaatgaa
     9661 tttcgataag tttaagtggg tataaactta tagaaattca ttttttattt aaggtaaaaa
     9721 tttaaagtaa aatattattt tacataataa taaccttata aattttgaaa ttacttatct
     9781 ttgtgttaaa ataagtaaaa tgcacatatt agagctaagt ttttaagtaa ataaacaaaa
     9841 tgaaaatata aatattaagg agatttggta tatgaatgtt tatgaaaaag gtaatggagt
     9901 tatactagaa ggagtaacag attttgaccc agtacatata tttgagtgtg gtcaatgttt
     9961 tagatggcac aaacaagaag atggctcata cactggagtt gcaaagggga gaatattaaa
    10021 tgtcaaaaaa gagaatgata aaatatattt aaataatact aatttaaagg agtttaacag
    10081 catttggtat aattactttg atttaggaac tgattataca gaaataaaga ataagctaaa
    10141 aaatatggat gaatatttaa ataaggctac tgaatttgga tggggaataa gaatattaag
    10201 acaagatgga tgggaaatgc ttatatcatt tataatttcc tctaataata ggattcctat
    10261 gatacaaaga gctatagaaa atttatcaag aaaatttggt aagtatatag gtgaatatga
    10321 aggtaatgaa tactatgcat tcccaacacc agaagaacta aataaggcct cacaagagga
    10381 aataagagca tgtcaaacag gttttagaga taagtacata aaaagtacta cacaggcagt
    10441 tatagagaat aatgatgagg tatctgaata tacaaattta agtactgagg attgtagaaa
    10501 agagctttta aaatttaatg gagtaggacc aaaagtatgt gattgtattg cattatttgg
    10561 tatgcaaaaa tatgattctt ttccagttga tgtttgggtt aagagagtta tgcaagaatt
    10621 ttatatagat gaagacatga gtttacctaa aatgagaact tatggaatcg ataaatttaa
    10681 agaaatgtct ggatttgctc aacagtactt attttactat gcaagagaac tcggtatagg
    10741 aaaataaatt aagggggaga aattatggga gtaataggaa caatatttct gttctattta
    10801 attatatcat atctagctgg agccataatt tctgtgatta tattgcttga aaatagagac
    10861 cctgcaaaaa caatgtcttg gctattgatg tttattatat ttccaggtgt aggtttaatg
    10921 atatatgcta tttcaggtag aaatattaga aaaagaaaat tatttaagac tcaaaaacta
    10981 gctaataata taaaagaaaa gaaactattt gatacattag aaaagataac agaaatagtt
    11041 gaattagaaa aagaatctat aaaacaaaat aagcttttaa gagatgaaga ggatggtagt
    11101 tatagaaaaa gggtaataaa tatgttgtta aagactggta tgtttccctt tactaaaaat
    11161 aataaagtgg atgtatttgt agatggaaat gaaaagttta aaagacttat agaagatata
    11221 agagaagcca aagaccatat tcatttagag tactttatca tcaaagatag tgaaataggt
    11281 agggtgttaa aagaagaact tataaaaaag gctaaagaag gcattaagat aagaatttta
    11341 tatgatgatg taggatgctg gagattttgg tttaatagaa aatttttccg agaaatgagg
    11401 gaagtaggta tagaaattgc agcattttta cctacaaaat ttcctataat aggagggaaa
    11461 ttaaactata gaaatcacag aaaaattgtt gttattgatg gaataattgg atatacaggt
    11521 ggaataaata taggagatga atatttaggc aaaaatgata agtttggata ttggagagat
    11581 actcatatta ggattaaggg tatttctgta tacatgcttc aaatgacatt tctgattgat
    11641 tggtattata cgacaaaaga agtattagtg actaaaaatt atttcccaag tgtagggaat
    11701 gttggtgaaa gtatgataca agttgttgcg agtggtccag acagtgactg ggaagatatt
    11761 cattatgctt atttttctgc aatatgtcag gctagaaaaa atgtttatat agaaactcca
    11821 tattttattc cagatgaaag tctactaaaa gctataaaga gtgctgctct tagtggagtt
    11881 gatgtgagaa taatatttcc taaaattgca gaccacaaga tagtaaatat agcatcttat
    11941 tcatattttg aagaaatatt aagagcaggt ggtaaagttt atttatataa taaaggattt
    12001 atacattcta aagtcgtaat aatagatgat aaaattgctt ctgcaggtac agctaatatg
    12061 gatttaagaa gttttatgct taactttgag gtaaatgcat ttatctatga tgaagaagtt
    12121 attagggtaa tgacagatga tttctttgag gatttaagtc actgtgaaga acttaatttg
    12181 gaggtattta agaatagaaa tatcatacaa aaaatcaaag aatctgtagc aagattattt
    12241 tcaccaatat tataaaaaat tattaaaaaa ggtattgaaa attatgtgtg attggtatat
    12301 tataataatt gttagcactc tattagatag agtgataata aataaaaagt atatatataa
    12361 atctacatat ataagtagta ttaatttaaa aataactaaa aacataggcg aactagtcta
    12421 tacttaatat tttaggaggc gtgaataatg aaaataagac cattagctga cagagtagta
    12481 attaaaaaag tagaagcaga agaaaaaact gcaagtggaa tagttttacc aggagcagct
    12541 aaagagcaac ctcaaatagc tgaagttgta gaagttggac caggtggaat agttgaaggg
    12601 aaagaaataa aaatggaatt gacagtggga gataaggtta tattccaaaa atattctgga
    12661 acagaagtta agatagaagg acaagaatac acaatactaa gacagagtga tgtattagct
    12721 gttattgaat aaatatagaa taaatttatt aggaggggtt taaaatggct aaagaaatta
    12781 aattttcaga ggaaacaaga agagctttag aagctggtgt aaataaatta gcagatacag
    12841 taaaagtaac attaggacct aaaggaagaa atgttatatt agataaaaaa tttggttctc
    12901 cacttataac taatgatgga gtaactatag caaaagagat agaactagaa gatagatttg
    12961 aaaatatggg tgctcaatta gttaaagaag tagcaactaa aactaatgat gtagctggag
    13021 atggtactac aactgctaca gttttagcac aagctataat aagagaaggt ttaaagaatg
    13081 taacagcagg ggctaaccca atacttttaa gaaaaggaat acaaaaagca gtaacagtag
    13141 cagtagaaga attaaaaaat caatcaagaa tagtagaaac acaagaggct atatctcaag
    13201 ttgcttctat atctgctggt gatgaagaag ttggaaaatt aatagcagaa gctatggaaa
    13261 tagtaggtaa agatggagtt ataactgttg aagagtctca aactatgaat actgaattag
    13321 atgctgttga aggtatgcag tttgatagag gatttgtttc tgcatatatg gttacagatg
    13381 tagataaaat ggaagcagtt ttaaatgacc catatatatt aattactgat aaaaaaatat
    13441 ctaacataca agaattatta ccagttcttg aacaaatagt tcaacaaggt aaaaagttat
    13501 tgataatagc tgaagatgta gaaggtgaag cattatctac attagtagta aataaattaa
    13561 gaggaacatt tgatgtagta gcagttaaag ctccaggctt tggagataga agaaaagaaa
    13621 tgcttcaaga tatagcaata cttacaggtg ctcaagtaat atcagaagaa ttaggttatg
    13681 atttaaaaga agctgattta tctatgctag gtagagcttc atctgttaag gtaactaaag
    13741 aaagtactac aatagtagat ggttctggag ataaaaaagc tatagaagat agagtaactc
    13801 aaattaaaca tcaagtagag caaactactt cagattttga tagagagaaa ttaatggaaa
    13861 gattagctaa acttgctgga ggagtagctg ttgtaaaagt tggagctgct acagaagtag
    13921 agttaaaaga aagaaagtta agaatagaag atgctcttaa tgcaactaga gcagctgtag
    13981 aagaaggaat agtagctggt ggaggaactg cttttgttag tgttatacca gcaataggaa
    14041 cactaattga gagtttagaa ggagaagtta aactaggtgc tcaaatagtt aaaaaagcgt
    14101 tagaagagcc attaagacaa atagctataa atgctggtct tgaaggtgct gtaattgtgc
    14161 aaaatgttgt taattctgaa gcagaaactg gatttgacgc attgaatgaa aaatatgtaa
    14221 atatgataga agctggtata gttgacccaa ctaaagttag tagaagtgct ttacaaaatg
    14281 ctgcatcaat agcaagtact ttcttaacta ctgaagctgc tgttgctgac cttcctgaaa
    14341 aagaagatgt aggaatgcca ggaatgggtg gcggaatgcc tggtatgatg taatttaaaa
    14401 aatttaaaat ataaatttta atataaagaa ctatttcgac ttagatttta aactctaagt
    14461 tgaaatagtt cttttgtata tatctaattt ttgtatatct ataaattcaa tacacatatt
    14521 tagataatca gtatctagtt tgtaataata ttttagagta gtattgttat tttttaggtt
    14581 atgattttag atatatatta attaaggtat aattgttgat agagaataaa tcaaatttaa
    14641 aaggatgcga taatatggac ttaagaaaat tgcttgaaga agttaaaaat gaaaatattg
    14701 atatagattt tgcgttagaa aagttaaaag atttacctta tgaagacctt ggatatgcaa
    14761 atatagacca tcatagagaa ttaagaaatg ggtatccgga agttatttat tgtgaaggta
    14821 agagtgatga gcatatttta gggattattg ataaaatgaa tcaaaaaagt tctaacatat
    14881 tggggacaag gtgcagaaaa gaaacttttc tgaaaattaa agaaatctat aatcatgctg
    14941 agtacgaaga ggcgtctaaa attcttaaga ttcaaaatca tgatatagag aatataggaa
    15001 aaggtaaaat tgtgattgct acagggggaa cttctgatat accagtagca gacgaagctt
    15061 atcatacagc taagttttta ggtaatgatg ttgatagaat atatgatgtt ggagtggcag
    15121 gtatacatag gcttttaaat aaaagacata aaatagatag tgctagagta atagtagccg
    15181 ttgcaggtat ggaaggtgct cttgcaagtg taattggtgg actggttgat gttccagtaa
    15241 tagctgttcc aacttctgtt ggatatggag caaattttgg aggattagca gcattactag
    15301 ctatgttaaa tagctgtgca tctggaatat ctgttgtaaa tattgataat ggatttggag
    15361 caggatattt agcatcaatg ataaataaac tgtaaataca ttgatataaa ttaaacaaaa
    15421 ctatataata aaatttaatt tctattatat ttttactatt aaaattgagg agacatatat
    15481 gagtgaaaaa atactttatt ttgatataat aagcggtata tcaggggata tgacccttgc
    15541 aagtttatta aatttaggtg tgcctaagga aatttttttg gaggaaattc ataaactaag
    15601 aatgagcgat gaatttaata taaacatcag ctcgaaaact gaaaatggaa tagtaggtac
    15661 aaaagtagaa gtaattacaa aagaaaaaca tacacataga aatttagtgg atatatttga
    15721 ggttatagat aaaagcactc taaacgaaaa tgtaaaatct aaagcaaaaa aaatatttat
    15781 ggtaattgga gaagcagaag caaaagttca tggaactaca atagacaaga tacattttca
    15841 tgaggtaggg gctatagatt caattgtaga tatagtagga gcttctatat tagttgactt
    15901 actttgtgta gataaagttt gtgctagtac agtgtctgtt ggttcaggat ttgtaaaatg
    15961 tgaacatgga attataccta tacctgcacc tgcaactata gaaattttaa aaggtgtgcc
    16021 aattaaatta aataatgtaa atggagaatg tacaactcca acaggagctg caatcataaa
    16081 agtcttgtgt gatgagtttg tagatgagct tgaattttct ccaaagcaaa ttggatatgg
    16141 tataggtcat aagaagtttg aagtaccaaa tatactcaga actgtattag gtgaaaaaaa
    16201 aaagaagaat taatttatga aattagtgca aacattgatg atatgtcttc agaaatctat
    16261 tcttatttgt atgaaaaaat attagatgag aaagcattag atatttatac agagagcatt
    16321 tatatgaaga agaatagacc agcaacaaaa gtatcaattt tatgtaatga atcagattta
    16381 gaaaaattta ttaaaatatt acttttagaa actagtactt ttggagtgag atataatgca
    16441 tataatagag aaattctaga gagaaaattt gtaaaattag atacaaaata tggagtggtt
    16501 acagtaaaac tagggtatta taaaggaaaa ctagtcaagg ctactccaga atataatgaa
    16561 tgtaaaacta tagcaaaaaa tgaagatatt cctataaaaa aagtgtttgc tgatataaat
    16621 tttagaataa aagaagaatt tagtgaaaac ttattgacat aagtaataaa ttttgataaa
    16681 ttaatattca gccttattaa ataaaagtaa acagaaaaaa atatataaaa tataaactca
    16741 ctcgtatatg ctcagaaata tggtctgaga gtctctacca agataccgta aatatcttga
    16801 ctatgagtga aattattata ccaaaagacc tagttaagta aatgtgtagg ctgagttaaa
    16861 ctccctatgt gttggctata agataaaggt attttggaag cctgtatagt aatttcactt
    16921 ttgctagaaa ttatggaagt tactatacag gttttttgtg taaaaagatt taatataatt
    16981 tagactgtat tgtgttaaaa taaatatata aaaactatat tatacaagga gagatgtaaa
    17041 tttatgaaac atgaattagt acttgtaata gattttggag gacaatataa tcagttgata
    17101 gctagaagag ttagagaaaa caacgtatat tgtgaaatac ttccatgtac tgcaagcata
    17161 gaaagaataa aagaaaaaaa tcctaaaggg ataatattta caggcggtcc aaatagtgcg
    17221 tatttagaag attctccaac aatatcaaaa gaaatatttg aactaggagt accaatactt
    17281 ggaatatgct atggtattca aataatgtct catgtattgg gtggagttgt aagaaaaggt
    17341 aataaacaag aaaaagaata tggaaaaaca gctataactt atggaaaatc atcattattt
    17401 gaaggaataa ctacaaatag tgtatggatg agtcatacag atttaataga aaaagttcca
    17461 gaaggattta ctatagttgc aaatactaat gattgtccag tagcagctat ggaaaatgta
    17521 gaacgaaacc tatatggagt tcaattccat ccagaggtag aacactgttt ggaaggggac
    17581 aagatactta caaacttctt atataatatt tgtaaagtaa aaggtgactg gactacagat
    17641 tcattcatag aagataaaat aaaagaatta aaagaaaaaa taggcgataa aaaagcttta
    17701 tgtgctttaa gtggaggagt tgattcttct gttgctgcag ttcttattca taaagcaatt
    17761 ggggacaact taacttgtat atttgttgac catggtttac ttagaaaaaa tgaaggaaat
    17821 gatgtagaaa gaatatttag agagaaattt gatataaatt taataagagt taatgcagaa
    17881 gatagattct tatctaaatt aaaaggagtt tctgaaccag aagctaagag aaaaataata
    17941 ggtgaagaat ttataagagt atttgaagaa gaatcaaata aattaggaaa aatggatttc
    18001 ttagtacaag gaacaatcta tccagatgtt atagaaagtg gacatggaaa tgctgctact
    18061 ataaagtctc atcataatgt tggtggaatc ccagaagatg tagacttcca agaaattgta
    18121 gaaccattaa gagagttatt taaggatgaa gttagaaaaa taggattaga gcttggtata
    18181 gaagaaggat taatatttag acatcctttc ccaggaccag gtctaggaat aagagttata
    18241 ggtgatgtaa ctaaagaaaa atgtgatata ttaagagaag ctgatgctgt ttatatggac
    18301 gagcttagaa aagcaggttt atacagagaa atatggcaag cttttgcaac attaccagat
    18361 gttaagactg ttggagttat gggtgatgaa agaacatatg cttatttagt tggtttaaga
    18421 gcagttactt cttctgatgg aatgacttct gactggtata agatgcctta tgatgtatta
    18481 gaaagaattt ctaatagaat aataaatgaa gttgatggag taaatagagt agtttatgat
    18541 ataacttcta aacctcctgg aactattgaa tgggaatagt aaataaaaaa gtcgtaagcc
    18601 ttgtattttc aaggtttgcg acttttaaaa aaatctttgt gatactaaaa tgatactata
    18661 tatttaaatt atctagtttt tgggcaactt caagttgctt atttgggtat aaatgtgaat
    18721 atgtattcca agttgtttct actttttcat gccccaatct ttctgctata gttaatatat
    18781 ttacatccat atttaccaat aatgacgcat gagaatgtct caaatcatgc actctaattc
    18841 tttttacatt agataactta cagcatctat ctagctcttt agaaagataa cttttagcaa
    18901 atttaaatat tctttcatta tcttttaagt catatagctt agatagataa tcttttatat
    18961 tattatataa gaaatgtggg atagggacaa cacgtttact tttaggagtt ttaggagaag
    19021 aaacaatatc ctctccattt agtcttatgt agcttttttc gacgcttatt ttattttcga
    19081 aaatatcttt tggagtaaga gctaacaact cccctagtct aagacctgtc caaaataaaa
    19141 tttcaaatgc tagtctaggt tctgatttct tttcaaattc aataaatttt ttaaactctt
    19201 ctaatgtcca aaagttcatt tcatctgcgt tttttttacc gatagaacct gccaaatgag
    19261 caggattaga aggtaagtta taatatttaa ctgcataatt taatacagca acaagctggt
    19321 tgtttatcgt tttaatatat gtttggctat aatcactttt taataattcg ttttgccatc
    19381 ttcttatatg tgttgcagta atttcattta tttttagact tttaaaaaaa ggtaaaattc
    19441 taaagtttat taaatacttt ttagtttcta atgtagataa ttttaatcta gaagacatat
    19501 cgtgcatgta ttcttctatg agactttcaa aactcatatc agtactcatt ttagatttat
    19561 tcaaaaattc tctttcaaac tctagagctt cttttttagt tttaaaacct ctcttaattt
    19621 tctttttcct atccccatcg aagtctgtaa aataaaagct agcataccaa ctttttcttt
    19681 gttcgtcttt gtaagcaggc attttagaca cccccaatta tgtcatttta atattacaat
    19741 aattataaca tgttagatat gctatctaaa taattgtttt attttcctct tctttttatt
    19801 tcttgaagct tgtaatattt acacagttct aagaagtctt cttctagtgc tatagataag
    19861 tctaatatcg tagatatacc tatatctttg tactcttgat tttctagttt tgatatataa
    19921 cttctgttac gtctcatttt ttctgctaat tctagttgtg tcattctttt cttttttctt
    19981 aattttttca acatttatta aaatccacct tttaattatt tttatgacat ttttataatt
    20041 aatagtttgt gtaatttctt gtaaaaaatg ttcctcatta gaacattttt tggtggaaaa
    20101 atgtgttaaa atgtaagtaa gaaaagcact ttcaaagcac tataaaaata gtgctgaaat
    20161 agataaacaa ataaaagtaa taaggaggaa agatagattc tagagggaaa tcattatcat
    20221 ttttaagaac gtatgttcgg ttggtgggat agaaaaatac tttacagggg atggtttatt
    20281 tgaatgagaa tgaaaatatg agtttatatg tcagtaagtt aaaagaagta ttgaaaaata
    20341 attcagaaga gtataaaaaa ataagagcta aaataaatga aatttataat ctaaatgaaa
    20401 agaaagaata aaagggcttt agctctttta ttctttctta gtattaactg ctttataata
    20461 agcattatct atcatttttt ttattgcatt tttatcatct gaatctaaag atgctaatct
    20521 atttattagt tcgttaactt cattatcttc ttttgagtta acttttttta ataattcatc
    20581 atcttgttga gtgttaggtt gtattttacc taatttagtt aatagctcct ttaaagttaa
    20641 atttaatcca aaactcattt tttcaagcat atctaaagta ggttcaacag ctttaccatt
    20701 ccttgggtct ctgttttttt ctatcttatc tatatatgta tggctcacac cacaaagatt
    20761 agaaaattct ctaagagata agttatgttc acttctatat tctttaataa tttctgctaa
    20821 tgtttgcata atttcacacc tcatctaagt aatagttgac ttaattatat cagaaaaatg
    20881 taaactattg ttaacaaaaa taaaaattta gtaaaaaata attgacaaga gtaaaaaaaa
    20941 gacgtatact atgattaaca aaaaggttat aaataaagtt aggagggatt aatataaaaa
    21001 ataatttaca atatattaga aaagaatcta gaatatcaca aaaaaaattc gctgataaga
    21061 taggtatatc aagaccgtat ttatctagaa tagaaaacgg taaggttaat ccgagtttag
    21121 aaatagcgca taaaatctcg ctcgaaacag ggaaaacaat aaatgaaatt ttttttgatt
    21181 ttactgtaaa tcatagtaaa ctataaggtt ttaattgtac cttgaaaact aaatataaaa
    21241 tattttaaag gagcaagtat atgaaaaata aagaaaaaga aataatcatt agaggaattt
    21301 taataggaat tttttatttt ttaggaattg tatttagtaa tacttttttt aaataataaa
    21361 tagaaggggt aggtgaaata ccaactcccc aaatcaaaat aacactttgg aagttaaata
    21421 taaaatattc aaaagaggtg attagatgca aagagagcaa acaacgcttc gtataccaga
    21481 agacttgcac aaagcgttga tagatttaag cagtgatata ggaatgccta ttacatctat
    21541 tataataatt gcatgttggt tgtatatatc aaagataaat taaccaatcc gatatgcaaa
    21601 atgaatgcac aacattattt attagagaat tgattgataa attattttct ttagctgttt
    21661 tctctagcaa ctcttttagg acaccaggaa tcctaagagt agaacgaaca gtatcatcac
    21721 ttttatacga gattgattga agttcattaa cttttgaatt tctaataata tcattaatag
    21781 cgtatagaat aagcgaagat ttgagaatgc ctgtttgata agaaattttt tctaaatttt
    21841 catttaatgg tgtatatatt cttacagtaa tagtagtcat tttgacacct ccctaatgac
    21901 attatacaaa aaatatttaa aaaagtcttg acactaaaat agtgtcataa tataatgatt
    21961 atagacagta aaacagtgtc ataaggaggg aggaataaga atggaaaaag taagaatgac
    22021 agtaaggctc gtcccaaaat taaatcaata tgtacagaat atagccaaag aatgtggaaa
    22081 aagtaaaaat tctattattg tggatgcatg ttgggagttt attgagaaaa taaaaaaaga
    22141 aaataaattc aatgtagaaa gcgaggaata aatatgaata atctacagat atttgaaaaa
    22201 ttggaatttg gacaaataag aatggcagag attgataata agccttactt tgtaggaaaa
    22261 gatgttgcaa agtcattagg ttataaaaat actaatgatg caattttaag acattgcaaa
    22321 ggggtagtga aacacgaggg gtttaaaatt aatggtatta agattgcttt gataactgag
    22381 ggtgatgttt atagattaat agtaggttca aatctaccaa atgcagaaaa gtttgagagt
    22441 tgggtgtttg atgaagtgct tccaagcata agagaaacag gtcaatacca agcacaacag
    22501 catgtaataa cagaacttac aggaactata ggagacttaa aaggaacaat aaaagaatat
    22561 aaaaagttgt gtaagataac atgctctaag aaacaacagt attctaaata cataaagaat
    22621 agactggata tagacaaagc taataaagaa tacaaccaag tgaaagcaag gctattccta
    22681 attcttggag ttgagaagtg ggaagacata gacttcgata catctaataa tttaatacaa
    22741 attatagatg attgtataag agttataaag tcagagagac catacaagca gttgagttat
    22801 tttgaaaact aaatacagaa tattttgaaa tatattgttt taattaatta ttaactagga
    22861 ggttaaatac atgaaaaata atataagcga ttcaagagta aaatattttt gcaagtgtcc
    22921 atactgtggg tttgataatg aggtagaagt taaaaaagga ttgaagccta aaatatgttg
    22981 catatgtaca aaagaagttg agtatgaaaa actggagcaa caaagtactc cagcaaaata
    23041 aaattaataa atatgaatat ttttacaaga atctaattct ttttctaact tattaacagc
    23101 atggttatat tgcagtgcct gttctgctat aaagttagaa tttgatatgt gttctttaca
    23161 catagggcat ggtagcccat tatcacaaac ttccctaaat ttagattctg ttatggtaac
    23221 ttttgtacca caatcgaaac aagtagcttc aattttagtt attttaccga tattcataaa
    23281 tcaccaccta atcatatatt tataggattt atcctacaaa tatagtatat caaaggaggg
    23341 aaataatggc aattaatgac aacataaata aaattttaag agatagaaat ttaaaagcgt
    23401 ggaaattagc aaaagaaata ggcgtagatt caggaaattt atatgcaatt ttaagaggag
    23461 aaaataaaaa tccaactata gatacattga taaaactagc tgactattta gatgttacat
    23521 tagacgaatt agttggaaga tagaaattaa atacagaata ttttgaaagt aggtgtattg
    23581 tatggcaaaa gcagtagcta aagaacaatt gttttatagg gcaaaagata tagctaagat
    23641 tttagatgta tgtgaagcaa ccgcttataa aataattgga gaattaaata aagaattaga
    23701 aaaagaaggt tttaagactt tttctggcag ggtatcagtt gcttatttta aagaaagata
    23761 ttgttataag ccaagaaagg gggtgattta gttgaatgta aaaggtacta atagcttata
    23821 tacagttttg caatgataag caaataaaag caagttttga aggtcttaga aaatacaaca
    23881 gagatataga gttagttaac ttgtatttac caagtaaatt aaaaataaat aaggaggtct
    23941 aattgtatat ggtatttaat ttagagaagt tcaaagtggg aaatgcgata agaataagtt
    24001 gtgaaagatt tggttttgaa attgattgta ttgtagtagt agcaacagaa aaagaattaa
    24061 atttagcata ctttgatgaa ggtagaggct gtatggagta tcaagcctta ataacagaag
    24121 atattcaaga tggtgattat gagattaaaa ttttatctta ggaggaaata aaatggcagc
    24181 tttaataatg gtaggtttat ttgcaatatg tttagtagga ttagtacaaa atagagatta
    24241 agtgaagggg tgtatttaga tggaagcagc tagattaata gcaatgggtc aaattaaaca
    24301 ggctgaaaaa gaaataagta aattgcaagg tacaaaaaac aatagtagtt taatgtggtg
    24361 ggaagccgta aaatttgcta gtcaaaatat attacaaggg ttggaacatg atatagagct
    24421 agaagcatca actgatttca gggagtttat gataacacaa gaagaacttg aaagagatag
    24481 acctatagat gtgcagatat aagaaaagag cctagggtga ggctcaattc aaataaatat
    24541 taaaaaattt aattaagcta attatagcat aaacggaggg aaattatgag tactttatat
    24601 gaattaacta cagatttatt agaaatagaa gaaggtttaa cagaaacaac aggaaatgaa
    24661 gctgaaaaac tagaggaaat aaaagaaata ataaaacaag agatacaaaa taaaaacact
    24721 aggatagttt cagtaatatt aaacattgac agtgatataa actctataga ttcagagatt
    24781 aaaagattgc aagagttaaa aagggtcaaa aagaatactc ttgatagatt aaaaagcaat
    24841 ataaaagact gtatggaatt acttggtact aaaaaagtag aaacagtttt aggaaatata
    24901 agtataagaa agtcagcagg tagcttagtc atagaagatg aagaaaagat acctgctata
    24961 tataaaacag tagagcaagt tgtaaaagta gataagaata c
//
LOCUS       DAGQVA010000056        24296 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.056, whole genome shotgun sequence.
ACCESSION   DAGQVA010000056 DAGQVA010000000
VERSION     DAGQVA010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.056"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            382..894
                     /locus_tag="MIV85_002578"
     CDS             382..894
                     /locus_tag="MIV85_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961908.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KMDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(1347..2444)
                     /locus_tag="MIV85_002579"
     CDS             complement(1347..2444)
                     /locus_tag="MIV85_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBY2961909.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            2737..4263
                     /gene="glpK"
                     /locus_tag="MIV85_002580"
     CDS             2737..4263
                     /gene="glpK"
                     /locus_tag="MIV85_002580"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBY2961910.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            4304..5419
                     /locus_tag="MIV85_002581"
     CDS             4304..5419
                     /locus_tag="MIV85_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBY2961911.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(5700..6464)
                     /locus_tag="MIV85_002582"
     CDS             complement(5700..6464)
                     /locus_tag="MIV85_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBY2961912.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            6723..6813
                     /locus_tag="MIV85_002583"
     tRNA            6723..6813
                     /locus_tag="MIV85_002583"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6757..6759,aa:Ser,seq:gct)
     gene            6901..7689
                     /locus_tag="MIV85_002584"
     CDS             6901..7689
                     /locus_tag="MIV85_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBY2961913.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLTFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            7710..8450
                     /locus_tag="MIV85_002585"
     CDS             7710..8450
                     /locus_tag="MIV85_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBY2961914.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            8626..9000
                     /locus_tag="MIV85_002586"
     CDS             8626..9000
                     /locus_tag="MIV85_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961915.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            9092..10552
                     /locus_tag="MIV85_002587"
     CDS             9092..10552
                     /locus_tag="MIV85_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBY2961916.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            10605..13634
                     /locus_tag="MIV85_002588"
     CDS             10605..13634
                     /locus_tag="MIV85_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2961917.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCAIILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            13711..15777
                     /locus_tag="MIV85_002589"
     CDS             13711..15777
                     /locus_tag="MIV85_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBY2961918.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    16160..16370
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16596..17411
                     /locus_tag="MIV85_002590"
     CDS             16596..17411
                     /locus_tag="MIV85_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBY2961919.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            17439..18116
                     /locus_tag="MIV85_002591"
     CDS             17439..18116
                     /locus_tag="MIV85_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBY2961920.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            18175..18897
                     /locus_tag="MIV85_002592"
     CDS             18175..18897
                     /locus_tag="MIV85_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBY2961921.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            19545..20696
                     /locus_tag="MIV85_002593"
     CDS             19545..20696
                     /locus_tag="MIV85_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBY2961922.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRLSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            20742..21917
                     /gene="thiI"
                     /locus_tag="MIV85_002594"
     CDS             20742..21917
                     /gene="thiI"
                     /locus_tag="MIV85_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBY2961923.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSILPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            22073..22876
                     /locus_tag="MIV85_002595"
     CDS             22073..22876
                     /locus_tag="MIV85_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBY2961924.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFSQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYSPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            23119..23760
                     /locus_tag="MIV85_002596"
     CDS             23119..23760
                     /locus_tag="MIV85_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBY2961925.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         9643 a         2480 c         4357 g         7816 t
ORIGIN      
        1 gaatattcag taaaatgatt ttgatatact ctctatattt tgtatgttaa aagtaaataa
       61 attattgtta aagaaggtaa agacttttaa atttcttatc ataggatttt aagtaaataa
      121 gaaggattgg agtaattaaa aatttttatt ttgcaaaaat aagtatttat ttatatggat
      181 aaatttgatt ttaaatctat aaatatagat aaaatctaat tatttaactt caactattcc
      241 tcaaaaaagc aacttttaag gaatagttga agcaaaaagt ttggttacat aatagtaatt
      301 ttagttacaa gaatgaaact gtaaaactta ggattttctt tatataattt cattgagaac
      361 atttaattta ggaggtaaga tatgaaagta aaaaaattta aaagtggtat agtaatggca
      421 ttaacagtaa tggcaattgg agcatcattg acaaatgtat cagctatgga attaaacaag
      481 agtaaagagt ttgaaactaa atacaatgaa atgaagatgg attttcaaga ggaatatgga
      541 aaagaagaca aatttaatat aacattggat gatgaattta caaaagaaga agtaaatgga
      601 gctaaaggga ttataaagac aactaataaa atgaataatg aggttgtagt attaaattat
      661 tttgatgaaa tgaaatctgg aattgaattt gagttgaagc caaaagcaga aaaaaatgca
      721 attttgagag atgaatttca acaaggttat ggaaaggaag ataaattcaa agttgtgtta
      781 gatgatgaat ttacaaaaga agaggtaaat ggagctaagg gcattataaa gactacagat
      841 aaagagacag gtgaggttat cgtatataat tactttgatg agcttgaaaa ataatgctta
      901 aagattactt tgattgaatg aaaaggtaat tgtgttgaga atataaaatg actgaataaa
      961 aacagttgta tcaaaacaaa caataataga atgtaagaat gattgtgttg aaaatattaa
     1021 atgactgaat aaaaaacgat tgtgtcaaaa ataaaaaata attaagtgta agaatgattg
     1081 tatcaagaat ataaaatgac tgaataaaaa acgattgcgt caaaaataaa aaacaattaa
     1141 atgtaagaat aattatgtca aaaatataaa ataaattaaa agaaaaagat tatattgaag
     1201 gaaaaagatt tgaaataggg gtgaacttta catattatag ttcaccctta tacaaaaata
     1261 taaaatataa tttattatag gaaaatttaa aaaaatcagt ctatttaatt tatactgata
     1321 tattgtagga ttttacaaac aaactgttat ataacttttt ttatctccaa ttttgatttt
     1381 aagatatcta agaatttata acaatcttct ggatatattt ctcccatatt tgctacttgg
     1441 aatatattag catctaggaa tttacctttt cctggataga caacatagcc actttccctt
     1501 tctagcccta atataaactc atttacattg atttctttag gtagaaatac agatgttact
     1561 gtattagaca tatacttatc tggaagtaaa aatgttagac ccaattcttc cataccattc
     1621 cttaaaatag cagaacattc tttgtatctt tctattttac tgtcatcttc caaaaactca
     1681 gttaaagctt cattaagggc aaatattaaa gtaacattag gtgtatttgg tgtttgagaa
     1741 gatgatttag caactttata gtgtttataa agattaagat acacattctt acattgattt
     1801 tctttaatat tttgtaaaat actctcttta gcacaaaggt atgcagaacc tggaaatgct
     1861 ccaagagctt tgccaccaac acctgttatt atatctatat taaactcttc cacatcaata
     1921 tattcacctg ctgaggcact tattgcatct acaaaaaata ttttgttata cttcttagca
     1981 agttttccta gttcagggac tggatttatc attcctgaac tagtttcatg gaacaccata
     2041 gcaattactt ttatatcaga attttcaatt atgtattttt ctaaaatgtc taggtccggg
     2101 tattctgccc attcaaaatt aggtttatat gtttttacat tataagtaga taatatttct
     2161 tctagccttt ctccaaaaac accattacta actagcagaa ctgcatcttc tttgtcaaag
     2221 atagaagata gtacacattc atttacagat gttccagagc cagatacaat taatgagtag
     2281 taattagaag ttgcattata tagtttattg attttttgtt gtgtatcttt gaataaatcc
     2341 ataaactcat ttcctctatg gcatatatca tagtgaagaa gtgaatttct gactttatct
     2401 gtaaccatta ctggtccagg actgaataga tatgtttttt tcattgtaaa gcctccttaa
     2461 aaagttaaat ttaaattttt gaatgactga ttatgtgtaa atattaaaat attatgtgtt
     2521 attttaacta gattatagaa taaaataata aatattgcaa taatatttca ataaaaatac
     2581 ttttttaatc actataatta aaaataacaa aaaatattgt aatgaatatt gcataaatcc
     2641 acatgatgat ataaaatata aataacttga atagattata tattcaaaaa ataaaaaaga
     2701 atttattaat tctgaaaata aagggggaca tttaaagtga aatatgtatt agcaattgac
     2761 caaggaacaa caggaacaag agcagtattg ataaacgaaa aatcagagtt tgtttttagc
     2821 gattatatgg aacatactca aatatatcca caatctggat atgttgaaca tgaccctata
     2881 gaaatttgga ataatacaaa aactgtgagt aataatgtat tacaacaggc ttttgaaaat
     2941 ggaatcaatg aaagtgatat aaaaggaatt ggtatagata atcaaggtga aacagtaatg
     3001 ttatgggata aaaatacagg taaaccactt tacaatgcta ttgtgtggca gtgcaggaga
     3061 acttatgatt atgtggaaaa tttaaagaat ataccaggtt tagaaaataa gataatagat
     3121 aagactgggt taattataga cccatatttc tcaggtacaa aaattaaatg ggtaatagat
     3181 aatgtaaaag gtgtaaaaga aaaaattaaa aatggagaag tacttgcagg aacattagat
     3241 agttggttaa tatggaaaat gacaggagga aaatcttttt taactgatgt atctacagca
     3301 gcaagaacaa tgctttttaa tataagagat atggattggg atagagagtt gcttgacatt
     3361 ataggagtac ctagaagtat tttagcagat ataatgccta cgagtggtga ttttggaact
     3421 acagataagg aggcattttg tggggtttct ataaaaatta ctgcttcaat ggtagaccaa
     3481 ccagcagctt tatttggcaa tggatgtttt gaaccaggaa tggttaaaaa tacttatggt
     3541 acaggatgtt tcctatatat gaatataggt gaggaactaa atatagcagg taatggtatt
     3601 ttgacaactg ttgcttggaa aataggagat aaagttacat atgcttatga tggtggagtg
     3661 tatatagcag gtgctgcaat acaatggctt agagatggca ttggagttat aaaaaattat
     3721 tcagaaactg atgacatggc aaattccata tcaagtactg gaggtgtata ttttgtacca
     3781 gcatttgcag gtatagcagc accttattgg gaccaatatg ctagaggtac aatggttgga
     3841 ataacaggaa gtactaaaaa agagcatata gtaagagcga ctcttgagtc tgttgcactt
     3901 caagtcaaag atgttgttga ttctatgaac ttagcctcag ggaaaaaaat aaaaatgttg
     3961 agagtagatg gtggaattac taaaaataac tttacaatgc aatttcaatc cgacatatta
     4021 ggtataccaa ttgaaattgc agaaaatcct gagacgacag tacttggagt aggatatatg
     4081 gcaggtcttt cttgtggtgt ctggaacagt attgatgaaa ttagaagtga atttacaata
     4141 agcaaaaaat atattccaaa tatgactact caaaaaagag aagaaatatt acttggatgg
     4201 aaccaagcag taaaaagagc tatgaattgg gaaaacgata ccaaaaaggt gtgtgctaat
     4261 taagttacaa tagagtattt tacatgtata ggaggaatta aaaatgccct ttgataaaat
     4321 tatattatac ataatggctg tgggagtgct tttaggagcg ttagatagaa taattggaaa
     4381 taaatttgga cttggcgagc agtttgaaga agggtttaat tcaatgggtc cattggcttt
     4441 aggaatggtt ggtatagttt gtttagctcc agtaatttca gatgtactag gtcctataat
     4501 aataccaatc ttcaatctct gtggagctga cccatctatg tttgcaacta ttttagcgaa
     4561 tgatatggga gggtatccat tggctatgga acttgcacac aataaagagg caggaatgct
     4621 tgcaggattg gttgtgtcat ccatgcttgg atgtacatta gtattttcaa ttccagtagg
     4681 actaggtctt atagaatatg aagacagacc attctttgca aaagggttac tgataggctt
     4741 gataacaata ccttttggag gtattatagg aggattaata gcaggattta acttatcaat
     4801 ggtaattata aatatgatac cagtgataat attggcagta atattggcag taggtttaaa
     4861 atttaattct acgcttatga taaatgggtc attagttttt ggaaaattta tatctatatt
     4921 gataacgata ggtttgggag cagcagcatt tcaagaaata acaggtatag tacttataaa
     4981 aggcatgaca cctataagag aaggtattca agtaattgga agtattgcaa tcgtgttatt
     5041 aggtactttt ccaatattac atttattagt taaagttctt aataaaccac ttacaatagt
     5101 gggtggaaaa ttaggtatgg atgccactag tgcagcagga ttagttttta ctttagccaa
     5161 tagtattcca gtatataaaa tgatgaaaga tatgagtcca aaggggaaag tagtaaatac
     5221 tgcttggctg gtttgtgcta cagcagcttt gggggaccat ttaggattta cagcaggagt
     5281 agttccagag atgattacac ctgttgtaat tggaaaattg gttggaggag tattggcaat
     5341 tgcacttgct atacttatga caaaagattt aaccttggaa gaagaacaaa gtattaaaat
     5401 gaagaaagat gcagtgtaga ataaacaata cttaagtcaa atttaaatta ttttaaagta
     5461 ggagtttaaa taactaaaaa taaattaaaa agacagacaa ttaaaaaata atcgaataac
     5521 taaaacttat aaattaaata aaatggcaat caaataacta aaaatgataa gctaactgaa
     5581 agtagttaca taattaaaat ataaagtata gtttagacat aaatggagct aaataaataa
     5641 ttatttggct ccttaatttt aatttattac atcaaggaac taaaaatcaa tcatataagc
     5701 taattatcag ctatgactaa aggtattcct ttttgagaaa actctattat tatattatgg
     5761 tctatactag cagaggtaat aatagtatct atatgttcta taggagctac tgatgcaaat
     5821 gaatttatac caaacttagg aggttcgaca actactatag attttctaga cctttcaatc
     5881 attttttttc taacaagtgc ttcttctaag tgatagtcag agattccatt ttcaagagtg
     5941 atacctccag cgcctaaaat agctttatca acattaaatt gttcaatagc tgacagtgta
     6001 agcggaccag aaaaagaacc ttcagtttct ctaagatagc ccccaagcac atatactttt
     6061 atattagtat tcataagctc gtttgcaact aaaattgagt tggttattac agttagattc
     6121 tttttatctt tcaaattttt tgaaacttca agtacagtag ttccagtatc cataaaaata
     6181 gtatcatttg tatttataaa ctcactacat ttaatagcaa tctgtttttt atcgtttgag
     6241 tttatttttt ttcttttaac atagttaagt tctacgctac ttgctataac tggtatagca
     6301 ccaccataaa ctctttttaa aagaccgata ctctccatat gggctaaatc tcttcgtgca
     6361 gtttctattg atatatcaaa catttgaact atgtcattta ttttaattat attatctgat
     6421 ttgagaatac ttaaaatctt ctcatatctt tcctgtggta acataaaata tcctccttgg
     6481 actagtatta ttttagtttt ggcataactt acaattaagt cagagtttag gtatatttgt
     6541 taatgtatgt atatttatca aataatatta taagtgttat gcaagataat tttaccatat
     6601 ttaaaactta catttaagca aaaaagtaaa aatagatgtt taataattca aaataactca
     6661 aattttataa aacaattgac taaaatatga ttttattata taatttacta gtatagagat
     6721 atggagaagt actcaagtgg ctcaagagga tcccctgcta agggattagg ctgggtaacc
     6781 ggtgcgaggg ttcgaatccc tccttctccg ccaattatta aaggctattt ttattaaaga
     6841 tagtcttttt ataatgtcat aaatgattag atatgtataa ctaaagaaag gagggaatag
     6901 atgacaactt taattttttt catagtgggg atagcatctt tggtagttgc ttttgttatt
     6961 gatgggggac atgttggagc attatttgta ttttcatcag cacttgttgt gtttggtgga
     7021 actataggag ctgttggagc ttcgactcca ttccctgtgt ttaaaaagtc tataaagata
     7081 atgttattaa cttttaaaaa taaaaagcct aataacatag aaaatataat ctatttcaaa
     7141 gaaattgcaa caaaggctag gaaagagggg cttcttagta ttgacaaaga aataagtgag
     7201 aatgatgaat tagacccttt tattagaaaa gggcttgaac ttatggtaga tggagtggat
     7261 gcagttacta taagaaatat attggaatca cagatacaga taacatcaaa acgacataaa
     7321 gaaggaatag caatttttga ttcagcaggt ggatatgcac ctacactggg gataataggt
     7381 acagttatgg gattagtaca tattttaggt aatctttcaa gtaatccaga tgcattagga
     7441 cctcaaattt ctgttgcatt tttggctact ttgtatggtg ttggttctgc caatttaata
     7501 tggttaccaa tagcatcaaa acttaaggct ataaatcaac aagaagtaag tgaaagactt
     7561 ttggtgatag aagcaatatt atccatactt gagggtgata attctaattt aatgacagaa
     7621 aaattaaaaa tatttttaaa ttcaaaagaa ctaattgaac ttgaagaaat tggtggtaga
     7681 gctgaataat ataaaaggat ggaatgttta tgttgtatga tgaagatgaa aaagaagaaa
     7741 acaatgagcg atggctttta acttattcag acctcataac attacttatg attttctttg
     7801 taataatgta ttctatgagt aatgttgatg cggagaaata taaacaatta tctcaatctc
     7861 taaattctgc ttttggtggt tcttctggag ttattgaagg tggtaatagc aagatagaac
     7921 cagtagttga accaggaagt aatgatttag atactttaca aaatgctaag tttaaaaaaa
     7981 ttggtgaaga aattcagaag tatttaaacg aaaatggtat ggctaattca gtatcattaa
     8041 gagttcaaga tagaggatta gtaataagcc ttaaagatac aatactattt gatacaggga
     8101 aagctattgt gaaggataat tctagagata agattattca aataggtaag atgttaaatg
     8161 aaatgaatag ttacatgaga gtagaaggcc atacagacaa tatgtctata aaaaattcag
     8221 agtttaagtc aaattgggat ttatcagtta tgagagcaac caatgttgtt caacttctta
     8281 ttgacaatgc aggtatagca ccagataaat tatctgctgt aggatatggt gagtttagac
     8341 caatagcaga aaattcatct gaagaaggta ggtcaaaaaa tagaagagtt gatatagttt
     8401 tagttgatag taaatatgat aatgtagaaa atgtttcaaa ggataaatag ttaaattagc
     8461 tgtctcaata cagaattaat tctaaaggag atggcttttt tatgcgaaaa tcaaaaatag
     8521 atacatagta agttaccttt ttgtaggaat atatggtatc ttaaatatat aatatttaaa
     8581 taatgtataa gctcaattaa aaaatttata gaggatggaa aataaatggg aaataaaaat
     8641 aaaaatacta aatataaaga taaaacaaga gaaaggtata ataaaaaagt tgagaattta
     8701 aataaagaaa aattaaataa aattaataag caatctaaga aagtagataa gattgatgat
     8761 attattaata aatctagtat tgtattatgt gtacttctag tagtgttttc attgctttac
     8821 ttatttaaac tggttcaact taatataata atgatacttt tagtaattac agtagctatt
     8881 caacaaggat tggtgtcatt tggtgcattt agaaataaaa attatgtaaa agctttattt
     8941 tctatatttg taatagtatg tttcttaatt gcttttaaat atgttgtaaa tcctgtttaa
     9001 atatatcaat aaacgttcta taattaatat aaatagtgaa gttacagttt taatgctatt
     9061 ataaatttta taatttgaag gagtagattt tatgaatagg tgtaagtttg caaaattaat
     9121 tatcacatca atgattgttt tattacttac aggatgtagt ttaaagaagg aagataatta
     9181 taagttagac ccagaaaatc cgacatcaat acaaatttgg cattattata atggacagca
     9241 gaaaatggct tttgataagc ttgttaagga atttaatgac actgtaggtg ctgaaaaagg
     9301 aattattgtt gaagcattca gtcaaggtaa tgtagttgat ttatcagaga aagttttaga
     9361 ttctgcaaat aaaaaagttg gttctgaaga tgtaccaaat atatttgcag catactcaga
     9421 tactgcatat gaaatggata aattagggtt actagtagat atggataagt acataagtaa
     9481 agaagaatta aatgaataca tagacgaata tgtagaagaa ggcagaataa attctaagga
     9541 tgagtttaaa cttttcccaa ttgcaaaatc aactgaaatt ttgatgttaa ataaaactga
     9601 ttgggataaa tttgcaaaag ctacaaattc aaatataaat gatataaaaa caattgaagg
     9661 attagtagag acatcaaaaa aatattatga atggacagat agtttaacga aagagcctaa
     9721 tgatggtaaa gcattttttg gaagagatgc tttagcaaat tatattatta taggaagtaa
     9781 acaactagga gtagaaattt tttctgttaa agatggtaaa gttacactaa atattgatga
     9841 aaaagttatg aaaaaactat gggataattt ctatgtacca tatataaatg gatattttgc
     9901 ttcttatggt aagtttcgtt ctgatgatgc aaaaacaggt gatatattag ctcttgtagg
     9961 ttctagttca ggagcagcat actttccaga tagagtaatg ctaaatgata atgagagtta
    10021 taatattgaa acatctgttt ttcaagcacc acgttttaaa ggagaaggaa aatatgctgt
    10081 acaacaaggt gcaggaatgg ctgtaacaaa atctactaaa gaagaagaat atgcatcagt
    10141 agaattttta aaatggttta cagataaaga acctaatata aaattctcta ttgcttctgg
    10201 atacttacca gtaaagaaaa aaacgaatga tttggatgtt ataaaagaag ttatgaagaa
    10261 agataatttg agtttatctg ataaagttga aggttcaata gcctcatcta ttgaacagat
    10321 taacagttgt aatttatata ctaataaagc atttgatggt ggaactaaag ctagacaaat
    10381 acttgaatat tcaatgcttg ataaagctaa agaagattca aataaaataa atgaattagt
    10441 aaaaagtgga acttctaaga aggatgcagt agcacaattt aataatgata aaaattttaa
    10501 aacttggttt gaaagtttta aggctgagct tgaaaatgct ataaaaaaat agatgaattg
    10561 gcagttagtg tgttgacgag cacaaaggta taggtggaat gggtatggaa aacaatctaa
    10621 gaaaaaacaa ttcaataatg aaaaagatga tatttcccct aattattgtt atgctaattc
    10681 aaacaagttt attttgtgcc ataattttat ggggaggaac tattaagaaa ttaaatgata
    10741 attcgtttga catcttaaat gaaagagtaa ttaatcgtaa aaattatata caaaatgaaa
    10801 tgttacaaag atggtcaaat acaagtgaaa cggaagctac aattaattcc tctgtaaaaa
    10861 aagtattaaa tgaaaaaaat gccttaattg aggatgtagg caacaatgaa gaaattaaca
    10921 aagatattat aaaaagcata tcaaatgatt taatatatct tttgagaaaa aattctgtta
    10981 caggagcttt tataatccta agtgacaaaa atattaacga taagtcaata gatagtaaag
    11041 gtgaaataag taggacagga ttgtatataa gggatttaga ccctaagttt aatccaaatg
    11101 ataattctga tttgttaatt gagagaggtt catcagatat agcaagaagt tttggaatat
    11161 ctatggacag ttattgggaa cctaagtttt catttaaaag tgaaaatgag caagatggag
    11221 atgatttttt ttataaacca tttagagctg caattgataa tccaaatgta tcaagttcta
    11281 atttaggata ctggggaagt aagtttttat tgacaaatgc aggtgatagg cttatgacat
    11341 atacagttcc ccttatttat gaagatggaa ctgtatatgg agtacttgga atagatttaa
    11401 gtgtaaatta tttaagagaa ttacttccat actcagagat aaatggaaat aaaaagggta
    11461 attatatttt aggtgtagat agaaataatg atatggcctt tgaaaatgta atttcaaatg
    11521 gatactcatt aaaagaaaaa ttttgggatg gtttacattc taatttagag cagaaggaat
    11581 cgtataaaaa tatatataag attaaaaata aagataatga atgtggtaat ggcaacattt
    11641 atgctagtgt acaatacttg gatttatata actccaatac tccatttgaa aatgaacgtt
    11701 gggctctttt gggtattatt gaagaaaaaa gtcttttgtc attttcaaaa agggtagaga
    11761 aattagttat aatatctata gcaatttctt tattaatagg tctaataggt atttacattg
    11821 catcaagatt atttacaaaa ccaattgttc ttttagccaa caaagttaga aacagtaatc
    11881 catcaaaacc agtaaatctt gataagataa atatatctga aatagatgaa ttatcttcag
    11941 ctatagagtt gctcagtgca aatgttgcag attcttcgtc aaaattatca cagattattg
    12001 aaatggtaga tatgccaatt ggggcttttg agttatacaa aaacgcagag aatgtttttt
    12061 gtacaaaaga attttttagc gtgtttacta ctgaaatcaa atttgaagaa tatggatata
    12121 tggaaaaaaa taagttcctg aaaaaattaa ggggactaga taaatatttg caagaaagtt
    12181 atgaaacaga aaatacatat atatataagt ttgaatctaa agataaaaaa cttaagtgga
    12241 taagaatgaa tatctttgaa gatgagctaa aggttcttgg tgttgttgtt gatgtcacaa
    12301 aagaatttat tgagaaaagg aagatagaat atgaaagaga ttttgatatt ttaacgaatc
    12361 ttttaaatag gagagctttt cattcacaga tacaagaaaa atttaagaat aaagatgaac
    12421 ttaagatagc agcatttatt atgtgggatt tagataatct aaaatatatt aatgatacat
    12481 atggacatga tgctggtgat gaatatatta ggtgtgctgc agacatactt aagaagttta
    12541 tatcatggaa tggtatagta tctagacttt caggtgatga gttttatgta tttatatatg
    12601 gatatgaaag caaagatagt ataagagata ttattaattc tgttaagaaa cagatgaata
    12661 ataccttatt aaaacttcat gatggaacag aatttaaaat aagggcatca gcaggaattt
    12721 cctggtaccc tgatgactca accaactatg atgaattaat gagatacgca gattttgcta
    12781 tgtatcaaat taaaaataca atcaagggtg aagttagtga atttgatatt aatatatata
    12841 ataaggattc attcttattg agtaatagag aagaattaaa caagttaatt gatggtcaat
    12901 tagttgagta tgcatttcag cctattgtag attgtaaagg taaagtattt gcatatgaag
    12961 cacttatgag acctaaaata aaaactttta gttcaccaat agatgtcatt agattagctc
    13021 gttcacagtc taaattatat caaattgagc gtattacatg gtttaaagca cttaaatcat
    13081 ttaaaaaata caaagaaaaa tttggcgatt gcaaattgtt cttaaattct attcctaata
    13141 ataatttgtc aaaagtagat tttgaggaaa ttgaagattt atatggtgaa tatttaaata
    13201 gagtagtact agaaataaca gagaatgata agattaatga agattttatt gaaaaaaaga
    13261 aagcatatat agaccattgg aatatagaaa ttgctttaga tgattttggg acaggttaca
    13321 acggagatgc tgtactatta tatataatgc cagactatgt aaagattgat atgtctattg
    13381 taagaggtat tgataaagat gaaaacagac agaaaatatt aaaaaatctt atctcatatt
    13441 ctaacgaaag aaatattaaa gtgatagcag aaggtgtaga aacaaaaggt gaaatggaaa
    13501 cactaattaa tcttggagta gattatatgc aaggctacta tattagtaaa ccatcattta
    13561 tacctgaaga tataagcgac aaaattaaaa aagaactcaa gatatgtcat gaaaatagga
    13621 atgatgtggt ttaatagagg aaaaattaaa tttattttta tgaactttta gtttataatt
    13681 aaaaagaaaa taatataatt ataaatcaag gtggtggagc taataatcac aacaaatata
    13741 gatataagaa agttaaatga aaatcaatta gaagcagttg agcatataga tgggccttgc
    13801 atgatacttg cagggcctgg ttcaggtaag accagagtaa ttacatatag aatagccaat
    13861 atggttgtaa acaaaaacat agcaccaaca agaatcttgg caataagttt taccaaggca
    13921 tcttcaatag aaatgaaaaa tagagctttg aatttaagtg atgacataag acttaataag
    13981 gtaacctatg gtacttttca ctctgtattt tttaaaattc taagatactt tgaaagatac
    14041 aacttagaca gtatatttga tgaaaagtca aagcgaatga caatcaaggc aatcctaaaa
    14101 agtttaaata tagagaatgc tgatgatgat gagaatatag gacaagttat aaatgaaatt
    14161 tcctatgtaa aaaatgaact tatggataaa aatgaattta attcagaagt attaacaaaa
    14221 gatgagtttt taaaagtata caacttatac gaagaacaaa aatctaaagt taataaaata
    14281 gattttgatg atatgcttat aagaacttat tatttacttt tgaacaataa gtctgcacta
    14341 gaaatggtta gaaatgtgta taaatatata ttgatagatg aatttcaaga tataaataaa
    14401 gtacagtttg aagttttaaa gttaatttgt agcccattaa acaatatatt tgcagttgga
    14461 gatgaagacc aaagtatata tggatttaga ggtgctagac cagatttttt gcttgaattt
    14521 gaacaatact ttaataatac taaaaaaata atattagata taaattacag gtctaaaagt
    14581 gagatagtgc atactgcaaa tagacttatc gacaaaaata aaaatagata tgaaaaaatc
    14641 attaagtgta gtcaggggga tggaggaagt gttacctata tttctccaca tgattcagag
    14701 gaagaagcct tatatattgc cagggaaata attgacgaaa tacaaaaaga ttatgtagag
    14761 tattcagatt ttgcagtaat ttatagaact aatatacagt caagagcatt agtagatgta
    14821 tttatggata tgaggattcc atttgtagta aaagactcag taattacaat atatgaccat
    14881 tgggcaagtc aagatatact agcctattta agaataggta ttaatccaaa atcaaataaa
    14941 gattggttga gaattataaa caagcctttt agatatatat ccaaagacag tataaatatg
    15001 gttaaggatg aaaaagactt tataacagca ttaataaata agtgtaatct tcatcctaaa
    15061 caagttaaaa caataaatga tttggaaata gatttaagtt atttaaatac tttaaatcct
    15121 aaaaatgcaa tatcttatat tagaactagt cttgattatg atagatatgt tttagattat
    15181 tgtagcaaca gaaagataaa gactaatgga cttgtagaga tattaaatga acttgagagt
    15241 tcagcaacta attttaatac tgttacagag tttttagagc atattgatag agtaaagact
    15301 gagttaacgg aaaataacaa gaataagcag actgagggtg tcatatttac aactatgcat
    15361 agtgcaaaag gattagaatt tagaaatgtt tatattatag gtgtaaatga aggaacaata
    15421 cctcatgaaa aatcatatga tatttgtaag gaagagaaaa aagaagaaca attagaagaa
    15481 gaaagaagac ttatgtatgt tgctattaca agagctgaag aaaagttatg tataagctct
    15541 actttaaata agtatggtaa gaaagttgat aaatcattat ttattaatga tataaaatct
    15601 ccaacgaaaa aagaaattga cagtattggt gtaggggata aggtatacca taaaaaattt
    15661 catgaaggag aaataattaa aaaagatgga attatgttta caataaagtt taaagataga
    15721 gagcgaatct tggatttgaa aacttgttta ttgaagaata taatttatac tatttaattt
    15781 agaatctaaa tttagataga aatataatgt attatttatt atgtgcaaga caaatagata
    15841 tgtgtaaaat gtattattta acttattaga aaaagaaata agggtttaat atattattta
    15901 tagttgttta gaaaaagcaa caatgtggaa aatattattt agtattatta aagaaaagca
    15961 acaatgtgaa agatattatt tagtattatt taagaaatag ctaaaaatat gaaatatact
    16021 atttataatt acacaaataa tatcaataaa tataaacagt agtatttaga taatttacaa
    16081 gtaaaaatta ttaaaaaaat aaaaaactta ttgacaaaaa tattataagg aagtacaatt
    16141 gtattaacaa tttaaggaaa caaatccaat gatagagaaa gtagcatata tggatttaca
    16201 gcgagttagg ggttggtgta agcctaacaa tgaagtctat gtgaagagag ctctggagga
    16261 gattatcaga aactttagta tgataattgg tttacccgcc ttaagggatt gagaggataa
    16321 gtacttactt atcaaaaaga gtggtaacgc ggatataatt cgtctcttag ctgtaaagct
    16381 aagggacttt tttgatttta aaataaaaat atccatacag cttaaaagct aacagtcaca
    16441 aattttgaaa gtaatataag tatttatcaa taagagtggt aacgcggtaa agtcgtctct
    16501 tagtcattaa agactgagag actttttttg taactcgaaa catttaagta ttaaaatctg
    16561 agggaaatta taattaaaag agaggggtag ttaaaatgaa agtatttaaa aaattattaa
    16621 gtttaggatt agtattagga ttgacattat cgctagtagg atgtagtggt ggaggagaaa
    16681 aaacaaagtt agaacaaata aaagacaatg gaaaattagt tgttggtact agtgcagaat
    16741 ttcctccatt tgaatttcat aaggtagtag atggaaaaga ttcaataaaa ggattcgata
    16801 taatgttggc tgaagaattt gcaaaagagc ttggtgtaaa ggttgaaatt aaggatatgt
    16861 catttgatgg attaataggt gctttaaatg cagaccaagt tgatattgtt cttgcaggta
    16921 tgtctccaac accagagaga gaaaagagtg ttgatttttc agaattatat tatttaagta
    16981 gaaatgcagt tatagttaaa gatgcagata tagacaaagt aaaaactgaa gatgatttaa
    17041 agaaacttag agttggagtt caagcaggaa gtatccaaga agaatatgta gttaacactt
    17101 taaaaatgac aactacaaaa tctttgaaag caatacctga tttaattaca gaattaaaaa
    17161 atggaaacat agatgcagtt gttactaatg aagcagtttc tttaataaat gttaaaaaat
    17221 atgatggaat aaaaatggca aatactgaag ttgggaaaga tgtaacagaa ggtatggcag
    17281 cagcaatcaa aaaatctgac aataacaaag attttataga attattaaac aaaaagataa
    17341 aagaattaca agatggcaag aagatagaag aatttttaaa tgaagcatct actgaagctg
    17401 cttcaaatta gtaagaaagt tatgtgggag atgaaattat gagtttagat tttagttttt
    17461 taagtagatt tgggacttct tttttggaag gaacaggtgt gacagtatca atttctcttg
    17521 tggcattatg ctttggattt ataataggta taattatctg tatggcaaaa atatcaaaga
    17581 gcaaagtatt aagagcaata tcatcaatct atattgaggt tttaagaggg acaccattat
    17641 tagtacagat atatatagta tggtttggtt tacctcaatt aggaataaga ttccctatgt
    17701 tgtttggtat accaagtgaa tttatagcta gtgcatttgc attatcagta aactctggtg
    17761 catacgtggc agagatactt agatcaggta tacaatcagt tgataatgga caaatggaag
    17821 caagtagatc attaggatta aattattggt caactatgag atatataata atacctcaag
    17881 ctataaaaaa tatattacct tcattagcaa atgagtttat tacacttgta aaagaatctt
    17941 caataatatc tgtaatagga gttgttgaga taatgcgtac tgctgatata gtaaaaaatg
    18001 cagcatttag agcattagag ccattaatag tagcagcagc aatttacttt gttataacat
    18061 ttactctatc aagattagtt ggattattag aaaagaaact atctgtgtct aactagatga
    18121 gagcatgttt agcatttagg gaaaacatag aatagtaaaa aggaaagtga taatatgatt
    18181 acaataaaaa atttaagtaa atcttttgga gatttaaatg tattaaaaaa tatagactta
    18241 gaaatcgcta aaggcgaaat aatggttata gtaggtccaa gtggttctgg taaaagtaca
    18301 cttcttagat gtatgaattt actagaaata cctacaggtg gagaaataat atttgaagga
    18361 aaaaatttgg tcgataaaaa aactaatatt gatgaggtta gacaaaatat aggtatggtg
    18421 tttcagaact ttaatttatt cccacataag actattttag ataatataac attagcacca
    18481 attaaattaa aaaagatgac taaggaagaa gcagaaaaaa aagcagaaat tttgttgagt
    18541 agagttggtc ttttagataa aaaagattca tatccatcac aattatctgg aggacaaaag
    18601 caaagaatag caatagctag agcacttgct atggaaccag atatgatgtt gtttgatgag
    18661 ccaacatctg ctcttgaccc agaaatggta aacgaagttt tggatgttat aaaagaactt
    18721 gctaaagaag gtatgacaat ggcaattgta actcatgaga tgggatttgc taaggaagtt
    18781 gcagatagag ttatttttat agatggagga agtatacttg aagataatac tccagaagaa
    18841 gttttcggaa atccaaaaca tgaaagaaca aaagcgtttt tagcaaaagt gctataatat
    18901 ataaaaagga tgttattgat attagaaatt caatacatcc ttttttagtg atggttaata
    18961 ttaattttaa aattaaagtt atattaatat taactttatt tttacgattt tttgcagaaa
    19021 aaaaaagagc tcggggtaag ctcttttttt ccaccgaatt aatttccgtt actaatccga
    19081 tttttaataa atataaaata tatccttatg aaagggtatt gggaatagat atattaacta
    19141 actagggtta ccagggggat aaccttaatt tattataaca aaatgcgaca caaaaatcaa
    19201 tatttttttt gaaataaatt ataaaagtta tttttataac aagtaagctt ataaatttaa
    19261 cttttatagt aaaaataagt atatgtataa tataatatat ttattttata taatatatta
    19321 ttttatcata tattgtattt tataatatat ttttgtaggg tatagtataa gtatattata
    19381 ttttactata aaaatttgta ataaagtgaa aaaactagct tttcatgaaa taatatttta
    19441 taatttaaga ttgtcttttt aataaagatt aacaaaaaaa atactataat tagtggtata
    19501 atagttagag ttgaagattt taaataaagg taggtgtaat taagttggaa atatacttag
    19561 acaatagcgc aactacaaaa ccttatcaag aagttataga taaaatggtt tatgcactta
    19621 atacggaata tggaaatcct tcttctgtcc atagaaaagg tgtagaagtt gaaaaagcta
    19681 taaaagaagt aagacaagat atagctaaat ctctaggagc gaaagaaaag gagatttatt
    19741 ttacatcagg tggtacagag tgtaataata ctataataag aggtattact agtttaaata
    19801 aaaaaagaaa aaatcacata atatctacta acatagaaca tccttctgtt ttaaatacat
    19861 taaaagattt agaagaagat ggttttgaag taacttattt agaggtcgga aaagatggga
    19921 aaataaatat agaggattta aaaaatgcga taaagtcaac tacatgctta gtaagcatga
    19981 tgcatgttaa caatgaaata ggaactatac agccaatagg tgaagttgga aagtatttga
    20041 agggtttaaa agaaaaaatt tatttccatg ttgatgctat tcagtcatat ggaaaaatta
    20101 attttagact atctaaatac aatatagatt ttatgagtgt aagtgcacat aaatttcatg
    20161 gtccaaaggg aattggattt atgtatataa aagaaaataa tcgccttaag cctatgttaa
    20221 caggtggtgg tcaggaaatt ggaattaggt cgggaacaga aaatgtacct ggaatatatg
    20281 gtcttggaga agctgttaga atactaaaca aagatttaga tgttgttatt tcgaaagtaa
    20341 ataacttaaa aaatatatta aaaaatgaaa taattgataa tatagaagat ataaaaatta
    20401 attctccaga agatggagta tgtcatatat taaatgtatc atttagaggg acaaaaggag
    20461 aagttttact tcattactta gagcaaaagg gtatttatgt atcaactggc tctgcatgtt
    20521 cttctaaaaa gaaaggtagt tacgtattaa atgctatagg tcttacaaat gaagaaataa
    20581 atggaacaat aagatttagt ttatctgata tgaatacaga agaagaaatg ttagaagctg
    20641 tgaaagtttt gaaagaatca atttgtgact taaggtcaat aatgaaaaga aaataaagaa
    20701 tactgtatag atagtgataa taaattagtt taagaggtga aatggtgtat aatatattaa
    20761 tagtaaagta tggagaaatt ggagtaaaag gaaagaatag atatatattt gagaataggc
    20821 ttataagaaa cataagaaat atgttaaaac caattggaag atttaatgta tataaagagt
    20881 atggaagaat atatgttgat ttagaagact atgattatga agaagtaatt gaagaagtta
    20941 gaaaagtatt tgggatagtg ggtgtgtgcc ctggagtaag agctaaaaaa gattatgata
    21001 cattaaaaga aatagcttta aaaatgttag aagaaaaaat agaggctgga tataaaactt
    21061 ttaaggtaga gtcaagaaga ggagataagt ctttcgggtt gacttctcaa gaaatgagta
    21121 tggatatagg tggatactta ttatcaaagg taggagatag gattaatgtt gatgtaagaa
    21181 atccagaagt taaaataaag tgcgaataca gagaatttca tactatggtc tatagtgata
    21241 ctatacctgg atatggtgga ttgccacttg gaacgaatgg tagagctatg tctcttttat
    21301 caggaggtat agatagccca gtagctacat ggatggttgc aaaaagaggt atggaagtag
    21361 aggcagttca ctttcatagt tatccattta caagtgaaag gtcacaggaa aaagttaagg
    21421 atttagctaa aatactggca aaatactgtg gtagagtaag gcttcataaa gttaatatct
    21481 tagaaataca aaaagcaatt ggcgagaatt gtaatgaaga agaagctact attctttcaa
    21541 gaagatttat gatgaggata gcacagagac tttctgaaaa aagacattgt gatgctttaa
    21601 ttacaggtga aagtattggg caggttgcat ctcaaactat acaaggactt acttgtacta
    21661 atgccgttgt agacttacca gtgtttagac cacttatagc aatggataaa tcagatatag
    21721 ttgatatagc caaaaaaata gggacttttg aaacatctat attgcctgaa gaagattgtt
    21781 gtagtgtatt ttctcctaga aagcccgtca ctaaacctag attagagaaa atagaaaaat
    21841 ctgaaacagc acttgacatt gaaaaattag tacaggatgc tattgacaaa atagaggtag
    21901 aggatattga gttttagcat acaagttatt taattactaa attgaatatt gagtatatta
    21961 gtagttctgt aagtatatta gtagttctgt tgaaaggatt tatgtagaca atttattaat
    22021 atgtagtatt taaaaataag tactataatt ttatttaatg ggaatgatta ttatgaataa
    22081 aaagggtttt acactaattg aattgttagt agttatatct ataataggca ttttagttat
    22141 agtagctgtt ccagcattgt ttagaaatat agaaaaaagt aaagcagtta catgtctttc
    22201 taatagagaa aatataaaga ctcaaattgt tattgcaatg gctgaggaat caagtaaagg
    22261 caagaatgaa gtcatgaaag aggtattaga aaacaaagat ggtaagtact ttgaaacaga
    22321 accaaagtgt aagtcaggtg gaatatattc agcaacgttt gatgatggtt atgatggaat
    22381 aactggaata gaaagcattg caaaagtgta tgttacttgt acaaaacatc cagatggtgt
    22441 tgaaatggct agggatatac atcaaagtat gaaagatttg attgcatcat tttcacaaga
    22501 cccttctata ataccaggag cctcaaaggg taatgatgat tttagaaaat atttattaga
    22561 caataaatat aaaaatgggt ggcctacaat tccagatgaa tttaaggcaa aatatggatt
    22621 aagtaaggat acactatata tacaaccata tgcatatagt cctactaaat ctgatgctac
    22681 tgtagttgta tttgcaaata ataagactgg gggtaattgg tatacttccc tagtttacga
    22741 ttatgatgaa ggtagatggt ataaaggtaa aaatggtatt tctgttgcag gtaggtcatg
    22801 ggatgttgac acagatagtg ttaagtctgt aaaaacagag attcattcta aagagggatg
    22861 gggtccttta aattaatata tcatgtttta ttaatctggt attgattaaa ctatagaaaa
    22921 gagcagtttc tatagatgac gaataccaga ttttcattta tatatataat tgagatatat
    22981 taaaagtgtt tatattttta agtcttcaca tacaagctaa aaataattat aataatattg
    23041 taaagaaatt taattataag attaattttc tgaagattta gtatttgtac taagaaatac
    23101 ataaaaaggg gaatagatat gaataataat tttcaagaca accaaacaat aaatttaata
    23161 caaagtcgta gaagtatacg aaaatttacg acagaacaaa ttagtgatga gcaagtaaac
    23221 acattattac actgtgcatt tgcagcacct tcaggatgta ataaacagcc ttggcacata
    23281 actgttgtgc aagaccagaa acttttaaaa gagattagtg atgatacttt atctaggatt
    23341 catgaggtga gtaatgttga gataaataaa aactttaagt tattttatgg tgctccaacc
    23401 gttttattta tttcttatga tgaaagtagt tcatgggctc catatgatat aggaatactt
    23461 acagggaata taacaacagc tgcacaagca ctagggcttg gaagttgtat aataggaatg
    23521 gttagaggtt tatttacacc tgttgaacaa ggggatattg aaggtcttgt gagtgtattg
    23581 gataaagaag atgtaaaaga atcagagtca ataaagatga agtttgatac aaataaaaaa
    23641 tacagagaac tacttgatat accagaaggg tattctgtac catttggtat tgctgtaggt
    23701 attccagatg gaaatttacc aaatgctaga gaggtagttt ataaagtttc cagagtttag
    23761 gataaagtat tgcaagaacc aatcagttac ttgaagaatt aaaccagtaa tatacaaata
    23821 aattgatgga agaggaagct atttaaaaag tagtttagat ttttcgttgt aaaataatta
    23881 aataaagaat aaggtgataa gtattttatt tattatctta ttctttttta tttttgtttt
    23941 gtagaatgat aaaaataagg attaagtgta ataaaataga aaacaagtat gttaatttta
    24001 agtatatgct ttaaaattta tccaagttaa aaatttaaga tatcttttca gtataatgga
    24061 aaaaatgtca aaatattgaa atagggaaaa aatagtgata taataagaaa aaatagagaa
    24121 aaaaagtaac ccttagttat aaaaaagtta ctatttattg aaaatttaga tatttttcta
    24181 aaaattatct atgttaatag ttaaatttat gaacattttt tgtttttatg ttaggatatt
    24241 tcttagaaat gaaatacttc ttaatttgat ttgatatgta tatttttata gctatt
//
LOCUS       DAGQVA010000057        23917 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.057, whole genome shotgun sequence.
ACCESSION   DAGQVA010000057 DAGQVA010000000
VERSION     DAGQVA010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.057"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            190..1377
                     /locus_tag="MIV85_002597"
     CDS             190..1377
                     /locus_tag="MIV85_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBY2961926.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            1393..2976
                     /locus_tag="MIV85_002598"
     CDS             1393..2976
                     /locus_tag="MIV85_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBY2961927.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            3004..4332
                     /gene="ssnA"
                     /locus_tag="MIV85_002599"
     CDS             3004..4332
                     /gene="ssnA"
                     /locus_tag="MIV85_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBY2961928.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            4477..5829
                     /locus_tag="MIV85_002600"
     CDS             4477..5829
                     /locus_tag="MIV85_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBY2961929.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            6021..7130
                     /locus_tag="MIV85_002601"
     CDS             6021..7130
                     /locus_tag="MIV85_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2961930.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            7413..8804
                     /gene="hydA"
                     /locus_tag="MIV85_002602"
     CDS             7413..8804
                     /gene="hydA"
                     /locus_tag="MIV85_002602"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBY2961931.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            8798..11359
                     /gene="xdh"
                     /locus_tag="MIV85_002603"
     CDS             8798..11359
                     /gene="xdh"
                     /locus_tag="MIV85_002603"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBY2961932.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            11511..12857
                     /gene="rpoN"
                     /locus_tag="MIV85_002604"
     CDS             11511..12857
                     /gene="rpoN"
                     /locus_tag="MIV85_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBY2961933.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            13655..14677
                     /locus_tag="MIV85_002605"
     CDS             13655..14677
                     /locus_tag="MIV85_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBY2961934.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            14737..15744
                     /gene="gap"
                     /locus_tag="MIV85_002606"
     CDS             14737..15744
                     /gene="gap"
                     /locus_tag="MIV85_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBY2961935.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            15966..17168
                     /locus_tag="MIV85_002607"
     CDS             15966..17168
                     /locus_tag="MIV85_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBY2961936.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            17194..17937
                     /locus_tag="MIV85_002608"
     CDS             17194..17937
                     /locus_tag="MIV85_002608"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBY2961937.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEIKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            17946..19478
                     /locus_tag="MIV85_002609"
     CDS             17946..19478
                     /locus_tag="MIV85_002609"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBY2961938.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            20066..21358
                     /gene="eno"
                     /locus_tag="MIV85_002610"
     CDS             20066..21358
                     /gene="eno"
                     /locus_tag="MIV85_002610"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBY2961939.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            21951..22175
                     /gene="secG"
                     /locus_tag="MIV85_002611"
     CDS             21951..22175
                     /gene="secG"
                     /locus_tag="MIV85_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBY2961940.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(22559..23497)
                     /locus_tag="MIV85_002612"
     CDS             complement(22559..23497)
                     /locus_tag="MIV85_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBY2961941.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(23485..23883)
                     /locus_tag="MIV85_002613"
     CDS             complement(23485..23883)
                     /locus_tag="MIV85_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBY2961942.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNIK
                     INLNIKGYKFLPYVKNLQASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT         9556 a         2728 c         4617 g         7016 t
ORIGIN      
        1 ttcaaaataa aaactaaata aaattaaata aaaccaaata aaattaaaat aaagtctaaa
       61 taaaaattta ataaataaaa tataaagaaa taaaaaatca atagattaag tgaaatgcta
      121 ataaattaaa aaagtgaaat atcaaaataa aacgtcaaca aactaaaaat tatatggggg
      181 aatatcaaaa tgttaaatga aacaagaaaa aaacaattaa ctgaagtatg ccaagactta
      241 ataagaaatg ctagttattc aggtcaagaa gaaaacgtag taaaagctat agaagaaaat
      301 tttgctttac taggttttga tagttggtca agagatagat atggaaatat agtaggatgt
      361 ataaaaggaa ataaaccagg taaaaaaata ttatttgacg ggcatataga tacagttcca
      421 gttccagatg caagtaaatg gagtgttcct ccttttgaag cgagaatagt agatgggaaa
      481 atatatggta gaggaacttc tgatatgaag gggcaagtaa gtgctatgat ggctgctgtt
      541 tcatactttg cagaagatac taacaaagac tttgaaggtg aattgtatgt agcaggtgtt
      601 gttcatgaag aaatatttga aggtgtttca gctagagaga taagtaaggc tgttcaacct
      661 gattatgttg taataggtga atcttcagaa ttaaacttaa agataggtca aagaggtaga
      721 ggagaaatag tagtagaaac ttttggtaaa ccagctcact ctgctaatcc agaaaaaggt
      781 ataaatgcag tttataaaat ggctaatgta atccaaaaga tacaacaatt agtacctcca
      841 actcatccag ttttaggtga tggaatatta gttttaacag atataaaatc ttctccatat
      901 ccaggagcat cagtagtgcc agattattgc aaagctactt ttgatagaag attattagtt
      961 ggagaaacaa gagaaggcgt attagctcca atacaagctt tattagatga aatgatgaaa
     1021 gaagacccag aattaaatgc aaaagtttct tatgcagttg aaaaagctga ttgctataca
     1081 ggaaatacta tagaaagtga aagattcttc ccaggttggt tatatgatga agaagatgaa
     1141 tttgttcaag cagcgtataa gggattaaaa gaagctggaa tagattcaga aataactcaa
     1201 tactcattct gtacgaatgg aagtcactac gcaggtgagg ctggaataag aactatagga
     1261 tttggtcctt ctaaggaaaa tcttgctcat acaatagatg agtatataga attagaccaa
     1321 ttattcaaag gtgcagaagg atattatggt atattaaaat cagtttataa aaaataatta
     1381 ggagatggtt ttgtgagaac tttaataaaa catgggctta tagtagatgg aaataaaaca
     1441 ccagcatatg aaggagatat tttaatagaa aacgagaaaa tattaaaaat atcacaagat
     1501 ttaaacgaag aagctgacaa agttatagat gcaaaaggta gagttatatg tccaggtttc
     1561 atagatactc atagccattc agacctagtt attttagtta atccatataa tgaggtaaag
     1621 attagacagg gaattacaac agaagtgttg ggccaagatg gtatatctat ggcccctcta
     1681 cctcaagagc atatatcttc ttggagaaaa aatttagcag gtctagatgg tgaaagtgat
     1741 gaaattgatt ggaaatatga aacaacagag aattatttaa aaatgatgga ttacaatggg
     1801 gtaggtttaa atgaaactta tttagtacct catggaaacg ttagaatgga agctatggga
     1861 cttgaagata gacctgctac taaagaagaa attcaaaaaa tgtgtgaaat cacagagaga
     1921 gaattaaaag caggagctat aggattgtct actggactta tatatatacc ttgtgcatac
     1981 tcattgactg aagaaattat agagatgtgt aaggtagtag caaaatatga cggagtattt
     2041 gtagttcacc aaagaagtga agcagataca attttaactt caatggaaga aatcatagaa
     2101 attggaaaac aatcaggagt aaaagttcat ttttcacatt ttaaggtttg tggtaaagca
     2161 aactggaagt atataccaca agttatagag cttttagaaa aagcagaaaa ggaaggaata
     2221 agagtatctt ttgaccaata tccatatgca gcaggaagta caatgcttgg agtagtttta
     2281 cctccttggg cacattctgg aggaactgat aagttaatag aaagattaag tgatgaaaac
     2341 gaaagagcaa aaatgaaaaa agatatagca aatggaatag aaggctggga taattttata
     2401 gaatttgctg gaatagacca aatatttgta acaagcgtaa aaacagaaaa gaataaagat
     2461 acaattggta agagcttatt agaaattgga aaaatgagag gaaaagaccc attagatgca
     2521 acgtttgatt tattaaaaga agaagaaaat gcagttggga tggtagattt ctatggatta
     2581 gaagaacata taataggatt catgaaaaga gacgagcaaa atgtgtgtac agatggtctt
     2641 ttagcaggta aaccacatcc aagagcttat ggttctttcc ctaaaatact aggaagatat
     2701 gttagagagt tgaatgtgtt aacaatcgaa gaagctgttt ataaaatgac taaaaaggca
     2761 gctacaagct ttagtataaa agatagaggc gaattaaaag aaggatattt tgcagatata
     2821 gttatatttg acaaggatac agttagtggt tgtgatgatt ttatcaactc tatgcagtac
     2881 cctacaggta tagattacgt aattataaat ggaaattgtg ttgttgaaga aggaaaatac
     2941 aataaaatta aagcaggaaa agtacttaaa aattaaatct tagctttaag gaggaataaa
     3001 tttatgattt tagtggggaa tgggaggcta ataagccaag attctttaaa tccctatatg
     3061 gaagatggat gtgtagtaat aaatgataat ctaattgaag atataggtac tacagaagaa
     3121 atgaaagcta aatatccagt acatgaattt atagatgcag gcaagaaaat aatcatgccg
     3181 ggtctaataa attcacatat gcatatatac agctcatttg ctagaggaat ggcagttcca
     3241 ggaaaacctt ctgagaactt tttagagata ctaaataatt tatggtggag acttgacaaa
     3301 cagcttacac tggaagatac aaaatacagt gcatatgcaa cgtatataga atgtataaaa
     3361 aatggtgtaa caacagttta tgaccatcat gcaagtccaa atgcaattga aggcagtttg
     3421 tttacaatat cagatgttgc aaaggatttg ggaattagaa cgtgtctttg ttatgaagtg
     3481 tctgatagag atggtggaaa tacaatccaa caaggtatca atgaaaacgt aaactttata
     3541 aaatacgctc aaaaagatga tacagacatg ataaaaggaa tgtttgggct tcatgctgca
     3601 tttacactat ctgatgatac attaaataaa tgtgcttcag agatggctgg tcttgataca
     3661 ggttaccatg tacatgttgc tgaaggacta gcagacttac aatataatgt agataaatat
     3721 ggaaaaaggg ttttagaaag attcaatgat tttggagtac taaaagaaaa aacaatagca
     3781 gttcattgta tatatataag tgcagaagaa atcagtcttt taaataaaac aaatacattt
     3841 gtagttcata atccagaatc taatatggga aatgcagttg gatgttctcc tgcaatagag
     3901 ttattaaaaa ggggagttac agtaggatta ggaactgatg gatatactag cgatatgttt
     3961 gaatcattaa aagttgccaa tataattcac aaacatcact taaaagaccc aagagttgga
     4021 tttgaagaat cacaaacaat gttatttgat aacaatagaa aaatagctaa agcttattat
     4081 aaaaatgacc taggagtact taaaaaaggt gcttatgcag atgttatagt agttgattat
     4141 ataccacata ctccattgac agaaaataca atagggggac acactatttt tggaatgagt
     4201 ggaagaagcg tagatacaac tattataaat ggaaaagtac ttatgaaaga tagaaagtta
     4261 ataaacatag atgaagaaag tattctagca aaaagtagag aattaagtca aaatctatgg
     4321 aatagaattt aaataattga tattaatata caagtaagaa acaagaattt agatgttaaa
     4381 aacagagctt aaacaaaaat aggaatttaa atgaagtata taaataaaaa atatacggaa
     4441 tagaatatta aattaaatat agaagggaga cccaaaatgt ctcgagataa aagccctaaa
     4501 atagctccag tagatgaaag gttacctgta tccaaatctt gggtattttc actacagcac
     4561 gttttagcaa tgtgtgcagg agcagtagca gttcctatga tgataggaag tgctgcacga
     4621 ctagatcatg ctagtattgt ttttttaata aatgcttgct tgtttatggc aggtatagga
     4681 acactcatac aaagtgttgg tataggaaat attgtaggtg ctaaaatacc agtaatagaa
     4741 ggaactagtt ttgccgctgt ggcaggtatg acagcaatag cctcatcata tagtgattca
     4801 caagttgcaa tacagacagt atttggctct gtaatagtag ctggattgtt ttgtatatta
     4861 cttgctccag tatttgaaaa attaataaga tttttcccta gtgtggttac tggaacagtt
     4921 gttatggtaa taggtatttc actatttcca gttgggataa aatggataac tgacaacaaa
     4981 ttggaagcgg ttgaaccaaa ctcattagca ttagctttag cagtattggc aataacttta
     5041 ctttcattta aattcttaaa aggaatttgg aatagcacag ctatattggt aggtatagta
     5101 cttggtacac tactttccat ggcagttgga atggcagatt ttagtgcagt aaatggagtt
     5161 ggttggctta acttaaatgt acctttaaaa tttggaatgc ctagatttga accatctgca
     5221 atactatcat tgtgtttgat tatgttggta cttatgacag aatcagttgg taatatgata
     5281 gctattcatg aaatggtaga caaagaagta acaggtaaaa atattaaaag aggtctattt
     5341 ggagatggaa tatctacagc attatctgga atattcaatt catttccaat aactccattt
     5401 ggtcaaaata caggaatagt aggtcttaca ggtataaaat caagatttat agcagtttac
     5461 gcaggggtta tattgctagt acttggattc ttaccaaaat ttgcagcaat aataggagca
     5521 atacctaagc ctgttcttgg aggcgtagga tttgcaatgt ttggaatggt aatggttgga
     5581 ggagtaaaaa ctttaagcaa agtgaaattt gatggaacta aaaatggggt tatagtagca
     5641 gttagtgttg gtttgtctat gataccacta acaaatcctg atttctatca taatttccca
     5701 acttgggtac aaacaatatt ccatagtgga ataacaacag gtagtttatc agcagtgctt
     5761 ttaaacatat tcttcaatga actaggttct aaaaaagaaa aaaataataa agttgaagaa
     5821 gcaaaataaa aataaaacaa gtaaaaatct atattgactt aaagtcatta agtattaata
     5881 aaaataattc agagatatta ataattcaac aaaactatct tatattttaa ataatataaa
     5941 aaagtaaata aataacgaat acaaataaaa gaatacaatc taaatattaa aaatatttaa
     6001 tttaagggag agataataat atggctaatt taaaagttaa tttatatggg atggaatttt
     6061 taaacccaat tatgacagcg gcaggacctg gagcaaaaga tggtgctctc tgtcaagagg
     6121 cagcaaaagg tggagcagga gctatatgta caaaaactat atctgtatta ccagctgatg
     6181 taccaagacc atgtatggca aaaactaata gtggtttttt aaacacagaa ttatggtcag
     6241 agcttccaaa agagcaatgg atagaggaag aatacaaaaa ggtaaaagaa acagggcttc
     6301 cagtaatagt aagtatggga tattcagcag agcaaatagc tgaggttgct cctttagtaa
     6361 agccttatgc agatgcagtt gaattatcta ctcattatgt aggtacagac gttgcaccaa
     6421 tagtaaatgc tttaaaagct gcaaaagctg ttttagatgt accagtattt atgaaaatga
     6481 gtcctcatac tgacattcaa actattgcaa aagctgttga agaagcaggt gcagatggac
     6541 ttgtaatgat aaactcattt ggaccatgta tggcaataga tgtaaataca ggatacccta
     6601 taatgggaag taaagctgga tacggatggt tatcaggtgc accaataaga cctctagcaa
     6661 taagatgtat atatgaagct tctcaagttg taaatatacc aataatcggt gttggtggaa
     6721 tcacttgtgg aaaagacgtg gctgaaatga tgatggctgg agcaagtgct gttcaagtat
     6781 gtacagaagc aatccttaaa gggccttcta tctatggaaa aattgctaaa gaattaaatg
     6841 aatttttaga tgagaatgga tatgctgatg ttaatgaaat aaaaggatta actcataaga
     6901 aaatggcagc tagagggttt agaactcatt cagtagctcc agtagtggat gataacaagt
     6961 gtatcaaatg taagcaatgt gtaacaagct gtgtatacga agctttagaa gttacagata
     7021 agttgaacat agatgcagac aagtgttttg gatgtggatt atgtgtaact agatgtccaa
     7081 aaggagcttt aagcatctgc tacaatcaag tagaagctat gaatgagtaa taattatata
     7141 gaattttggt aattaactta gagtaatagg tattaggata ataaaatata tcagataaac
     7201 aaacacacat tatgcattaa taatacagtc taaagttaat aattttatta tattgattta
     7261 actaaatatt agtttagctg aatattaatt taattaggta ttggtttaat cttaatatag
     7321 atttactacg tataagtgaa ctaactagat tactttaagt taattttttc atataaaata
     7381 aattgataca ttacaagtaa ggtggagtct atatgggaat tgttttaaaa ggtgggaaag
     7441 tagtaacaag tgaaaaaact tactgtgcag atgtaagaat agaagatgaa aaaatagtcg
     7501 atataggtct tgatatatca aaagaaaatg atgaaatagt tgatgttagt gattcttatg
     7561 ttataccagg aggtatagat acacacacac actttgactt agatacaggc gttactaaga
     7621 cagcagataa ctttgagaca ggaacaaaag ctgctatagt aggaggaact actactatat
     7681 tggattttgc tacacaagct aaaggatgtt ctttgaaaga cggattagaa gaatggcatg
     7741 aaaaagctaa ggataaatca tattcagatt atggctttca tatggctata acagattgga
     7801 atgactcggt ttgtaatgaa atggaggata tggtgaaaga gggagtatct tcatttaaac
     7861 tgtatatggc gtataaagga agccttcaag ttgatgatgg tgtaatcttt gaagcattga
     7921 gaaaagcaga agagatagga gggattattg gtttccattg tgaaaatggg gacataatat
     7981 gtgaacttgt ggataaagca aagtcagaaa ataatttatc tccaaaatat catcaattaa
     8041 ctagaccagc tataatggag gcagaagcta catcaagact tatgaagata gctgaagttg
     8101 caaactctaa agtatatgta gttcacttaa gctgtaaaga atccttagag gaggttttaa
     8161 aagctaagca aagaggtgtg gatgtaatag ttgaaacttg tcctcaatac cttctattaa
     8221 atgatgaatt atatgattta gatggatttg aaagtgctaa gtatgtaatg tcaccacctt
     8281 taagaaataa agaaaataat gaaatattat ggaatgctat tttagataat caaatagaca
     8341 ctataggaac agaccattgt tcttttaatt ataagggaca gaaggaactt gggataaacg
     8401 atttcagtaa gataccaaat ggttctccag gtgtagaaca taggatgagt cttttataca
     8461 catatggagt ctgtaaaaat aaaatatcta tcaacaagat ggtagaagta acatcaacta
     8521 atgcagcaaa gttgtttgga atgtatccta ataaaggaac tatagaaata ggcagtgatg
     8581 cagatatatt agtcttaaat ccaaacaaaa aatccaaaat agaagcaaaa aaacaattac
     8641 aaaatgtaga ttatacacct tatgaagggt atgaagtgga ttgtcaaata gaacatgttt
     8701 atttaagagg aaaagaagta gttagagatg gagaattaat ttgtaatact ccaagtggga
     8761 gatatataaa taggcgtcta acaaaggggg ctagagaatg gtagaattta tattaaatgg
     8821 agagaaagtt gttgcaaaag aaggcaaaaa acttttagac ttccttagag aagatatgaa
     8881 tataacttca gttaaaaatg gatgttcaga aggtgcttgt ggaacatgta tggttataat
     8941 agatggtaaa gctactaaag catgtgtatt taaaactgat aaattagctg ggaaaaacat
     9001 aacaactata gagggattat cagagagaga aagagatgtt tttgcatatt cttttgctag
     9061 tcaaggagct gtacaatgtg gattttgtat tccaggtatg gtaattagtt caaaagcact
     9121 tatagacgtt aataataatc ctactgaaga tgatataaag aaagctttaa aaggcaatat
     9181 atgtagatgt acagggtatg taaaaataat taaagctgtc gatttagcgg caaagatttt
     9241 tagagaaaat atagatgtgc caaaagtaaa ctgtaagggt ttagtaggtg aaaatcttcc
     9301 tagagttgat gcagttggca aagcacttgg atattctgaa tatgtagatg atatgagaat
     9361 tgagggtatg atttatggtt cagcagttag agctaagtat cctagagctt tagttaaaaa
     9421 aatagatata gaagaagcaa aagcttatcc aggagttgtt gcagttctaa cagctaaaga
     9481 tattccagga actataaagg tagggcactt aaagaaggat tgggatactt taataccaga
     9541 aggtgaaata actagatact taggagatgg aatagtttta gtagcagcag aaactagaga
     9601 agcgttagaa gaggccaaaa agctagttaa gatagattat gaggaattaa caccattaag
     9661 tactacagca gatgcactta gagaagatgc tccaaagata catgagacag ggaatatact
     9721 tgttaaggaa catttagtaa gaggaaacgc taaagaaaag atagaaaatt caaaatatgt
     9781 tgtaactaaa agatatacta cacctgctac agaacacgca tttttagagc ctgaatgtgc
     9841 agtagctggt ccttatgaag atgatggagt aataatctat tcaacagacc aaggggtgtt
     9901 tgccactcaa catgaatgtg cagatatgtt aggattacca tatgagaagg taagagttat
     9961 aaacaaaatg gtaggaggag ggtttggtgg aaaagaagac atgagtgttc aacaccatgc
    10021 agccttactt gcatatcata caaagagatt tgtaaaagta cagttaacaa gaaaagaaag
    10081 tattattgtt catccaaaac gacatgccac agaaatggaa tttacgacag catgtgatga
    10141 aaatggatac ttaacgggta tgaaggcaac gataatatct gatacaggtg catatgcctc
    10201 tcttggagga ccagtgctac aaagactgtg tactcatgca gcaggaccat acaattatca
    10261 agatattgat ataacaggaa cagcagtata tactaataac cctcctggag gagcatttag
    10321 aggatttgga gttacacaga gttgttttgc aactgaatgt aatctaaatt tacttgctga
    10381 aatggttgga atatctcctt gggagataag atataaaaat gcaataagac ctgggcaagt
    10441 tttaccaaat ggtcaatttg cagatgaagg aacagcaatg gcagagacac tagaagctgt
    10501 aaaagaagag tatgaaaagc atccacgtgc aggcatagct tgtgctatga aaaatagtgg
    10561 ggttggagtt ggtatacctg atgttggaag atgtagattg gtgataaaag atggcaaagt
    10621 tcacataaga acaagtgctt cttgtatagg tcaagggctt ggtactgtta tgactcaagt
    10681 agtttgtgaa actgctaacc tacttcctga aaatatagtg catgaagttc cagatactca
    10741 tttaacacca gactctggta atactacggc ttcaagacag acagtattta cgggagaagc
    10801 tactaaggtt gcatcaaata agttaaaaga agctttagac tctggcaaaa ctttacttga
    10861 tttagaggga gaagagtttt atggagaata tgaaagtatt acagataaaa tgggttgtga
    10921 caaagaaaat ccagtaagtc atgttgctta tggatatgca acacaagttg taattctgga
    10981 tgaaaatgga aaactagaaa aagtagtagc agcacatgat gttggaagag ctataaatcc
    11041 aatcagttta gaaggtcaaa tagaaggtgg agtagttatg ggtcttggat atgctctaac
    11101 cgaagattac ccagtagtca actctgttcc tacagctaag tttggtacat taggtttatt
    11161 taaatctaca gatataccag aaatacaagc tttaatagtt gaaaagaaca aagatttatt
    11221 ggcttatggg gcaaaaggtg taggagaaat ttgtacagtt cctactgcac cagcagtaca
    11281 aaatgcctat tatgtatttg ataaagaatt tagaactgag ctaccactac aaaatactcc
    11341 atatagtaaa aaaaagtaac aaaaaaaaga aatattaaat aaaaaaatag atgaaattgt
    11401 aaataaaaaa aacccttttg cataaggtat attttaaatg atagaatata catatacagg
    11461 agggtttttc ttttataaaa taagtttaat aaaattgaga ggtgagcaga atgaatttta
    11521 ataatagtct agaattaact cagtctcaga agctaataat gactacacaa cttaagcaat
    11581 cattatcaat attaaatatg agtaagttag agttagaaga agagataaaa agagaagcag
    11641 agaataaccc attagttgaa gtcgagaaaa gtggggagat aaattgggaa gagtatataa
    11701 aagacatgga taggtcaaga cgtttagata gaacagagat aagctataat cctgataatg
    11761 aagttaatct agaaaattta gttaaatatt cgtcaaattt atatgaagat ttaaaatttc
    11821 agataagcct gtataaactt acagacaaag aattggaagt ctgtgagtat ataattgata
    11881 gtttagatga ggatggatat ttaagaactg aggaaaaagt aattgttgat accttaaaga
    11941 tagatgaaga actttttgaa aaatgtttaa ttagtgttca gcagttggaa cctagtggag
    12001 taggggcaag aagtctttca gaatgtctga tgatacaaat ggctagttta ggaatatata
    12061 atgaaatttt agaggaaatc gttacaaaag acttaaattt aattgcaaat aataaataca
    12121 aagagataag taaaaagtac aatatgtcat tacaaaaatg tgttgaacta ataaacataa
    12181 ttaagacatt agaccccaaa ccaggaagaa cttgttcagt agagaaaagt gtatacattc
    12241 aacctgatgt aacagtagaa aaaattgatg atgaatttat tgtatattta aatgagaaag
    12301 attcttatca aataagaatc aatagttatt ataaagacat attaaaaaat tcacagtctg
    12361 atgaaagtgc aaaagaattt ataaaagaaa gactaaattc agcaacagga cttatgaaaa
    12421 atatagagag taggaaaact acagtactta agattgcaga agagatagta aaagctcaag
    12481 atgaattttt gagaaaaggg acaaaatata taaaaccttt gaaaatgaaa gacatagcag
    12541 aaaaattaga atttcatgaa tctactataa gtagaggtgt aaatggtaaa tatatgctaa
    12601 caccttttgg cgtatatgaa tttaggtact ttttcagtag cgccattgag actgagaata
    12661 atgaaatggc atctagtaca agcataaaaa aaattataaa ggaaacaata aaagacgaaa
    12721 ataaaaagaa acctttaagt gatgaccata tatctaagtt attaaaagaa aaaggaatca
    12781 atgttgcaag aaggacagtt gccaaatatc gtgaagaatt aggaatccca tcttcaagta
    12841 agagaaaaga atactaataa gtaaaagaca aatatcagta tggtaagggg aaaaggctaa
    12901 ttaagagatg aatgtagatt gggctaaaaa ttttataaag taaaataata gaatatggaa
    12961 aagtattaaa atgctataag gtattaaaaa actggggaac attaaaacat taagatagca
    13021 aagaacataa aaaactaaag aagattaaaa cattaaagaa cattagagct ttgaggaata
    13081 ttagaacttt aaagaatatt aaaatttata aaatataaaa atactaaaaa gaattgaaaa
    13141 actggggaac attaaaatat tgtaaaatgc taaaaaacta gaaaacataa ttaaataagt
    13201 gcttataaag aatgattaaa ttaaataagt gtttgtaaag aataattaga tattagaaaa
    13261 agaagaatac ctagataaat aaactattat taaatttaat aatcacaaaa ggaaaacacg
    13321 tagggtataa ataaaaatct taactagata aaagtaaact tagttgtaga taaaaataac
    13381 tagaaataaa agtaactaga aataaaatta tttatagtaa taaatattag aatgaaaata
    13441 taaaaaaata tatataaaaa gccttatata aaaagaaaaa atactgtgat ttgaaaatgg
    13501 tggagaaata ttttataaaa taaaaaaata aaaaagtttt tgaaaaacta ttgaaatcta
    13561 tacgcaaatc ctataaaata aaaatatctt gtgggactta aataaacact agggacaaaa
    13621 aaagtcccga aaggaaagca ataaggagta tgttatgaag aacttattag aaattcaaaa
    13681 gaaattgatt ccacaggcaa ttgaacttat ggaaagaaga tactctattt taagacaaat
    13741 atctttaagt gaaccaatag gtaggagaac attatcaaat gtattagaga ttagtgaaag
    13801 aataatcagg tcagaaactg agtttttaaa agaacaagga cttatagacg tagctgtatc
    13861 tgggatgact atcactaaag aaggttctga tttgttagat aaacttaagg acatcatgag
    13921 tgacatcatg ggattgtcta agttacaaga tagagtcaga gaaaagcttg gaataaaaag
    13981 ggtaatatta gttcctggaa gctgtgatga aaatggaagt ttactaaaag atgtaactag
    14041 atatggatgc gaatatttct taggcatttt aaaagatgga gatatcgttt caataacagg
    14101 aggaagcact atgttggagt tttcaaacgt tattaaaact gataagagat atccaaactc
    14161 tacaatagtt ccagctagag gaagtatggg aactgatgta gagatgcaat ctaacaatat
    14221 agttgcttca ataagtaaga aattacattc taattgcaaa cttttacata taccagatga
    14281 gttggatgaa agtgcaatga aaactcttag ccaagtgcca gagattaaga caactttgga
    14341 gtatattaaa agaacagaca ttttagtttt tagtataggt agagcagatg tcatggcaaa
    14401 gagaagaaaa cttccagaag acaaggttga tgagatatta tctaaaaatg cagttggaga
    14461 agcatttgga tattatttca acaaagatgg agaaatagtt tacaaactga acactgttgg
    14521 aattgattta gaaacagtta aacaagtaaa agaaactatt gcaatctttg cagggactga
    14581 aaaagtagaa gccttattag ctatatcaaa tatgcataaa aacatggttc ttgtaacaga
    14641 tgaagaaagt gcttataaga tattgtcatt attataaaag tcaagaccta gcacagagct
    14701 agaaaacata catttacttt ataggaggta gcgaaaatgg ttaaagtagc tataaatgga
    14761 tttggaagaa taggaagatt agcattaaga aaaatgatgg agcaacaaga taagttcgaa
    14821 gttgttgcaa taaacgactt aacagacgct aaaatgttag ctcatttatt taaatatgat
    14881 acagctcaag gaagatttaa cggagaaata gaagttaaag aaggtgcttt tgtagtaaac
    14941 ggaaaagaaa taaaagtaac agcagaaaga aatcctgctg acctaccatg ggctgaatta
    15001 ggagtagata tagtattaga atgtacagga ttctttacat ctaaagataa agctgaagct
    15061 catatacaag caggggctaa gaaagttgtt atatctgcac cagctactgg agatttaaaa
    15121 acaatagtat tcaacacaaa cagtgacata ttagatggtt ctgaaacagt tatatcagga
    15181 gcttcttgta ctactaactg tttagctcca atggctaaag tattaaatga taaatacggt
    15241 atagaaaaag gattaatgac tactatacat gcatacacta atgaccaaaa tactttagat
    15301 ggtcctcatc caaaaggtga tttaagaaga gctagagctg ctgctggaaa catagttcca
    15361 aacactacag gagctgcaaa agcaataggc ttagtaatac cttcattaaa aggaaaatta
    15421 gatggggcag cacaaagagt accagttgta actggttcaa taactgaatt agtttgtaca
    15481 ttaggaaaaa atgttacagt tgaagaaata aatgcagcta tgaaagaagc ttcaaacgaa
    15541 tctttcggat atactgaaga aatgttagta tcttctgaca taatcggaat aagctacggt
    15601 tcattatttg acgctactca aacaaaagtt atggaagtag atggaaaaca attagttaaa
    15661 gttgtttctt ggtatgataa tgaaatgtct tatacttctc aattaataag aactttagga
    15721 tactttgcac aattagcaaa atagtcagtt ttgagaaaat agaaaagtag attgacaaag
    15781 tccgagtttg tagtttaata ctacggactc aggacttttt ttaagaaaaa atatataaaa
    15841 tacacctaaa taatgttaca tactatatat aaaaatatga taatatgata tatttaatag
    15901 ggtaaaagta tgtactatat tatacttggc aataaaaaat tactttatta aaaggagaga
    15961 tatttatgtc aatgcttaac aaaaaaacta tagaagatat tgatgtgtgc ggaaaaaaag
    16021 tattagtaag atgtgacttt aatgtgccat tacaagatgg tgtaattact gatgaaaata
    16081 gattgaacgg agctttacca actattcaat atttaatttc taaaggggca aaagttatat
    16141 tatgctctca cttaggaaag ccaaaaggag aagctaaacc agaattatct ttagcaccag
    16201 tagcaaagag attatctgag atgttaggaa aagaagttgt atttgcagca gacgataatg
    16261 ttgtaggaga aaatgcaaag aaagcaactg aaaaaatgga aaacggagat gtagtattat
    16321 tagaaaatac tagatataga aaagaagaaa ctaaaaacga agagaatttc tctaaagaac
    16381 tagcatcact tgctgaaata tttgtaaatg atgcatttgg aactgctcat agagcacatt
    16441 gctcaacagt tggtgcaggc gagtttttac aagagagagt ttgtggatac ttaattcaaa
    16501 aagaattaaa attcttagga gaagctgttg caaaccctgt aagaccattt acagctatac
    16561 ttggaggagc taaagtttct gataaattag ctgttataaa cgaattatta gaaaaagttg
    16621 ataatctaat aataggtgga ggaatggctt atacattctt aaaagctcag ggttatgaag
    16681 taggaacttc tttacttgaa atagataaag ttgaatatgc taaagaaatg atggaaaaag
    16741 ctaagaataa gggtgttaac ttattattac cagtagacgt tgttatggca gaccactttg
    16801 caccagatgc tactccaata gtaacagaag atgctaatgt aaaagaagat tacatgggac
    16861 tagatatggg acctaagact atagcaaact ttgtaaaaac tataaaagaa tcaaaaactg
    16921 tagtatggaa tgggccaatg ggagtatttg aatttgaaaa ctttgcaaat ggtacattat
    16981 cagtagctag agctatggca gagttgactg atgcaactac tgtaattggc ggtggagata
    17041 gtgcagcagc agttaatcaa ttaggatttg gtgacaagat gactcacgta tcaacaggtg
    17101 gaggagcatc actagaattt ttagaaggta aagaattacc aggtattgca gcattagata
    17161 ataaataaac taatatatag aggagattgt aaaatgagaa aacctataat tgcaggaaac
    17221 tggaaaatgc ataaaacaat aaaagaagct ttagaatttg taaatgaaat taaagataaa
    17281 gtaaattctg ataaagtaga agctgttata tgtgcaccat ttactttatt aaaggattta
    17341 aaagaagcta ctaagggtac aaatataaag ataggtgctc aaaatatgca ctttgaagaa
    17401 aaaggagcat ttacaggaga agtttcacct cttatgttaa aagaaataga tatggactat
    17461 gttgtaatag gacattcaga aagaagacaa tacttcaatg aaactgatga aactgtaaac
    17521 aagaaagttt taaaagcatt agaagtagga atagacccaa tattatgtgt tggagaaact
    17581 ttagaacaaa gagaagctgg aaaaactaaa gatgtttgta aagttcaagt tgaaaaagct
    17641 ttagaaaatg ttcttaaaga tgatttagca aaagtagttg ttgcatatga gccaatctgg
    17701 gctattggaa ctggtaaaac tgcaactgct gaagatgcta atgacgttat atcttatata
    17761 agagaagtta taaaaggatt atatggagaa ttagctaatg aagttagaat acaatacggt
    17821 ggaagtgtta aaccttcaaa tgtagccgaa ataatgggtc aaagtgatat agatggagct
    17881 ttagtaggtg gagctagttt agctagtaat gattacctag accttgttaa tttctaagga
    17941 gtgaaatgat gaaaaaacca gttgctttaa ttattatgga cgggtttgga tacaataagg
    18001 atgttaaggg aaatgcaatt gctgagtcca aaactcctaa tttagataga ataaaaaaag
    18061 agtatccaaa cacattgata aatgctagtg gtcttgatgt tggtctacct gatggtcaaa
    18121 tgggaaattc agaagttgga cacactaaca taggtgcagg tagaatagta tatcaagatt
    18181 taactagaat aacaaaatct ataaaagatg gtgacttttt tactaataaa gttttatgtg
    18241 aagcaatgga taatgcaaaa gaaaattctc ttcatgtaat gggacttttg tctgatggag
    18301 gagtacattc acatatagac catcttaagg ctataatcaa aatggcaaaa gataaaggcg
    18361 tacaaaaggt gtatgttcac gcatttactg atggtagaga tactgaccct caaagtgcat
    18421 tagaatatgc caaagaagta caagctagta tggatgaaat tggagtaggt gaatttgcta
    18481 cagtttctgg tagatactac gctatggata gagataagag atgggaaaga gtagaacttg
    18541 catacaatgc catggttaga ggtattggtg aaaaagcaaa ttctattgag gaagctattc
    18601 aaaactctta tgatgatgga aaaaatgatg agtttataat gccaacagtt attatgaaag
    18661 atgataaacc agttggaagt ataaaggaaa atgattcaat tatattcttc aactttagac
    18721 cagatagagc tagacaaata actagagctt tagtttgtga agagtttgat ggatttaaaa
    18781 gagaagatat taaaaacttc tttgtatgct taacagagta cgatataact atagagaatg
    18841 tgcatatagc atttggacct caatctttag ccaacactct aggtgagtat ctagctaaaa
    18901 atggaaaaac tcaacttaga gctgctgaaa ctgaaaagta tgcacatgta actttcttct
    18961 tcaatggtgg agtagaagag ccaaataaag gtgaagaaag actattgata ccttctccaa
    19021 aggttgcaac ttatgattta aaaccagaaa tgtcagcata tgaattgaca gataaagctt
    19081 tagataaatt aggagaagat aagtttgact ttatagtatt aaactttgca aatcctgata
    19141 tggtaggtca tacaggaagt atagaagcgg ctataaaggc tgttgaaact gtagatactt
    19201 gtgtaggaaa attgatagat aaaatagtag agttaggtgg aagtgcaata ataactgctg
    19261 accacggaaa tgctgaatat atgttagacc cagaaacagg aaaaactgta acagctcact
    19321 ctattaatcc agtaccattt attgtagttg gtcaagaata tgaaagtgca aaattattgg
    19381 atggaggaag attatctgat atagcaccga ctgttttaga tatgatgaag ttagaaaagc
    19441 cagaagaaat gactggtcat tcacttattt caaaatagtc gattttgata agtagagaat
    19501 aatatataaa ctacaatata aatttaaaaa taatgcagtt taggtttatt ttgtaaagtt
    19561 tagactttat gacataaggt ttaaattttg taagttctgg atattgtaag gtgtagatga
    19621 agatatattt tataaaattt acaagataga caatttataa aataaaaaat tacaatatag
    19681 ataataatgt aaataatgat ataaataata acaagataga caataacaat ataaataata
    19741 ataattaata tatattatat aagcaaaaat tttagaatca ttagttgtac attttatgtt
    19801 taatgtttta aatctagtta taatatttgt gtatttaaga ttggttttgg attttagaca
    19861 agttttttta tattatataa attaaaatat tataaaaaat aaaataaaaa taggaacttt
    19921 tacaaattta cccatcaaat aaatttgtac ctaattttca aaagcaactt tatgtactat
    19981 aatatagaaa gtagattaaa atagtagacg gatgtttaca gtaaatgaaa atttaactaa
    20041 tagaaaatcg aagggagata tacaaatgtc agttattgaa ttagtatatg ctagagaagt
    20101 attagactca agaggaaatc caactgtaga agttgaagta gtattagaag atggagcaat
    20161 gggaagagca atagttccat caggagcatc tacaggagct tttgaagctg ttgaattaag
    20221 agatggagat aaaggaagat acttaggaaa aggtgtagaa acagctgttg ctaacgtaaa
    20281 tgaaataata gcacctgaaa tagaaggaat ggatgcattt gaccaaccag ctatagatgc
    20341 aatcatgata gaattagatg gaactccaaa caaaggtaaa ttaggagcta atgctatatt
    20401 aggtgtttca atggcagtag ctagagcagc tgctgatgaa ataggtttac cattattcca
    20461 atacttaggt ggagtaaatg ctaaacaatt acctgttcca atgatgaaca tattaaatgg
    20521 tggagagcat gctgataata acgttgatgt tcaagaattt atgatattac cagtaggagc
    20581 ttgttgtttc aaagaaggtt taagaatggg agcagaagta ttccattcat taaagaaagt
    20641 tttaggagaa aaaggattag cttgtggtgt aggtgacgaa ggtggatttg ctccaaactt
    20701 aggttcaaac agagaagctt tagaattaat agttgaagct ataacaaaag ctggatataa
    20761 gccaggtgaa gacgttatgt taggtcttga cgttgctgct acagaaatgt acaacaaaga
    20821 aactaaaaaa tacgttttag caggagaagg aaaagagtta actgctgctg aaatggttgc
    20881 tttatatgaa gattggtcaa acaacttccc aataataact atagaagatg gtttagacga
    20941 agaagattgg gatggatgga aattattaac tgaaaaatta ggaaataaat tacaattagt
    21001 tggtgacgac ttatttgtta ctaacacaga gagattagaa aaaggaattg aaaatggagt
    21061 agctaactct atattagtta aagttaatca aataggtaca ataactgaaa ctttagatgc
    21121 tatagaaatg gctaagagag caggatatac tgctgttata tctcacagat caggagaaac
    21181 tgaagattct actatagcag atttagctgt tgcagtaaat gctggtcaaa taaaaactgg
    21241 tgctccatca agaactgata gagttgctaa gtacaaccaa ttattaagaa tagaagaaat
    21301 ggttggagag caagctagat attgtggatt aaaatctttc tataacttaa aaaaatagtt
    21361 attaaaatgg ttactaaaaa agattaatga agagagaata taagatattt aagctcatct
    21421 tataagatat aaaagagata agtgttaatt gatttttcaa ttcacttatc cttttttata
    21481 ttttattact taattttatt catagattca gaaaaaatat gaataaatgt ttctatctca
    21541 tttttatcta attgcatagg aggtttttat taaaaaataa aagtgaagac atattttgat
    21601 ttaatcataa ttgtcattaa agtattattg ctaaatgtgg attatttatt ttaaattatg
    21661 ttgaaattaa aagttatatc aatattttaa aatgattgtt ttattttggt ggctatttat
    21721 aatatatgca atgagagtag attattttaa gtgttaattt atgtattaat ttaaatagtt
    21781 ttctcttcta agttttattc atttttatat tgagaatata gtaatatatt atagtaacaa
    21841 tatatttttt tgtatgttat ttatagcata atagtcttga aatggctata ttattgtgat
    21901 acactaaaga gtaatgaaat ttaagtaata aacagatagg aggggcaaga atgagcaaca
    21961 ttttaatggg tgtgcaagta gtactaggga ttttactagt aattagcata atgcctcaag
    22021 attctaagaa tgctttacct tcagaatttg gtggagaagg aagccaagct tactttaaac
    22081 caaaaggaaa acaagcattt cttgctagag ttacaaagat aacagcagta ttatttttta
    22141 taaatgcatt ggcattactt atagttaaga agtagtgata ttgttgaata actggccatt
    22201 atttaattag tgcatttgct agacatttaa aaattaaatt tagtttttaa taaaagtaca
    22261 tcaacataaa aagtacgtaa aataaaagct ggactaatga ttttatatga ttagtccagt
    22321 ttttatttta tagattgact atttgttggc gtttattatt tgtatttata tattgtttgt
    22381 atttatatat ttttttcaaa ctaaaaaata tatagcaaca ctactttcac catgtttaat
    22441 gagataatat acacaaagtt atattatata gtaaaaatag tataataata tgtttttacg
    22501 caattaaatc gattttatat atgtttctca taataccaat ttgtgttatc aaatatcatt
    22561 aaataagatt attctgcttt aaaataaata ttattaaaaa tactgtaatt atagaaaatc
    22621 cagaagtaaa tactacaatt tgtccagcta attcactgtc agaatccatc tgttgtgcca
    22681 ttgtaaatga agaaactgca gttggagcag ataacattat cataagtgaa gctaattcta
    22741 catttctaaa tccaagaaaa atgctaattg gtaaaaatat agcaggtaca agtataagtt
    22801 ttccacatac gcccaatata atggggttta tatgcccctt tatagcagaa aaactaaaag
    22861 agccacctag aattataagt gataaaggag tagctatttt agaaatatca ccaatagttt
    22921 tgtgtaaaaa tgtaggtata ttaatattta aaattagcat tgtcaatcct ataaaagagg
    22981 cgattatgag tggatttgtt aagacgcttt taatcatatg ttttatattt actttgccac
    23041 ctctaaaaat ttcaagaatt acaacagata atacattaaa cataggtaca ataactgcaa
    23101 ttaataaaga tgtgactcca atactcttat cgccaaatag tgaaattgtc acaggaatac
    23161 caaatataac gaaattgcta cgaaatacac cttgtattaa tgcacccctt gtcttattat
    23221 ctttttcaat tttaggaata ataaagacta agattaagaa gattgaaaaa ataattataa
    23281 cagctacagc cataagccta aaattaagag aaccatctaa atctgtattg tatatattaa
    23341 aaaataataa taatggcaag aaagacttga agcagacatt attcatttta tttaaagtat
    23401 gagtatcaaa tagacctaat ttttttagaa catatccaag tgacattgtg agaaacaaag
    23461 gaagaacaac atttattgat aggattaaat tttccaaggt ttactctccg tgattctatg
    23521 atttgataat tcaattaaat ttccattagt ttttttcaaa taaatagatt tcatattacc
    23581 aaagacacct gtacattcta caattcctcg cttaatttga atctcatttt gttctaagta
    23641 tttttttggc tcatcaatat ttgtgtttat tttaaaacat aagttatctc tacttgcttg
    23701 taaattttta acataaggta aaaatttata accttttatg ttaagattta tcttaatatt
    23761 tctagcatta agtttataat ttttgctcat ttctttagat gaaaaaccaa attttttata
    23821 aaaattgata taattttcta tattattatt agtaatgacc acatgttcta ttttttttat
    23881 catggcaact ccttaagatt ttatataagt tattaaa
//
LOCUS       DAGQVA010000058        23879 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.058, whole genome shotgun sequence.
ACCESSION   DAGQVA010000058 DAGQVA010000000
VERSION     DAGQVA010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23879
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.058"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..866
                     /locus_tag="MIV85_002614"
     CDS             <1..866
                     /locus_tag="MIV85_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2961943.1"
                     /translation="YKYILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIEN
                     ENLSKLYSQNLYDKLRISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGH
                     SLSTTIIQLNAIEKLLKDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSL
                     FKIKELVKSFIKLTNINVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIR
                     IFITFNTSNLIITISDNGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRAS
                     FPKFSGGDFFE"
     gene            859..1506
                     /locus_tag="MIV85_002615"
     CDS             859..1506
                     /locus_tag="MIV85_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961944.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            1635..2570
                     /locus_tag="MIV85_002616"
     CDS             1635..2570
                     /locus_tag="MIV85_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961945.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            2584..3681
                     /locus_tag="MIV85_002617"
     CDS             2584..3681
                     /locus_tag="MIV85_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961946.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            3684..4748
                     /locus_tag="MIV85_002618"
     CDS             3684..4748
                     /locus_tag="MIV85_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961947.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            4992..5489
                     /locus_tag="MIV85_002619"
     CDS             4992..5489
                     /locus_tag="MIV85_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBY2961948.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5665..5913)
                     /locus_tag="MIV85_002620"
     CDS             complement(5665..5913)
                     /locus_tag="MIV85_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961949.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(5979..6995)
                     /locus_tag="MIV85_002621"
     CDS             complement(5979..6995)
                     /locus_tag="MIV85_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBY2961950.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGIACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(7053..7820)
                     /locus_tag="MIV85_002622"
     CDS             complement(7053..7820)
                     /locus_tag="MIV85_002622"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBY2961951.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(7888..10077)
                     /locus_tag="MIV85_002623"
     CDS             complement(7888..10077)
                     /locus_tag="MIV85_002623"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBY2961952.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            complement(10651..11943)
                     /gene="brnQ"
                     /locus_tag="MIV85_002624"
     CDS             complement(10651..11943)
                     /gene="brnQ"
                     /locus_tag="MIV85_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBY2961953.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGIK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
     gene            complement(13062..14354)
                     /gene="brnQ"
                     /locus_tag="MIV85_002625"
     CDS             complement(13062..14354)
                     /gene="brnQ"
                     /locus_tag="MIV85_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBY2961954.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
     gene            complement(14743..15639)
                     /gene="ylqF"
                     /locus_tag="MIV85_002626"
     CDS             complement(14743..15639)
                     /gene="ylqF"
                     /locus_tag="MIV85_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBY2961955.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDAETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            complement(15960..16310)
                     /gene="rplS"
                     /locus_tag="MIV85_002627"
     CDS             complement(15960..16310)
                     /gene="rplS"
                     /locus_tag="MIV85_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBY2961956.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            complement(16495..17190)
                     /gene="trmD"
                     /locus_tag="MIV85_002628"
     CDS             complement(16495..17190)
                     /gene="trmD"
                     /locus_tag="MIV85_002628"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBY2961957.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            complement(17199..17714)
                     /gene="rimM"
                     /locus_tag="MIV85_002629"
     CDS             complement(17199..17714)
                     /gene="rimM"
                     /locus_tag="MIV85_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBY2961958.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            complement(17822..18049)
                     /locus_tag="MIV85_002630"
     CDS             complement(17822..18049)
                     /locus_tag="MIV85_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBY2961959.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            complement(18114..18386)
                     /gene="rpsP"
                     /locus_tag="MIV85_002631"
     CDS             complement(18114..18386)
                     /gene="rpsP"
                     /locus_tag="MIV85_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBY2961960.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            complement(18424..19776)
                     /gene="ffh"
                     /locus_tag="MIV85_002632"
     CDS             complement(18424..19776)
                     /gene="ffh"
                     /locus_tag="MIV85_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBY2961961.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            complement(19773..20141)
                     /locus_tag="MIV85_002633"
     CDS             complement(19773..20141)
                     /locus_tag="MIV85_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBY2961962.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            complement(20244..21524)
                     /gene="ftsY"
                     /locus_tag="MIV85_002634"
     CDS             complement(20244..21524)
                     /gene="ftsY"
                     /locus_tag="MIV85_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBY2961963.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            complement(21551..>23879)
                     /gene="smc"
                     /locus_tag="MIV85_002635"
     CDS             complement(21551..>23879)
                     /gene="smc"
                     /locus_tag="MIV85_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBY2961964.1"
                     /translation="ENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNENLKN
                     VNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNRGVK
                     EVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYLKQN
                     NLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTILIN
                     NIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTEKIS
                     NIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEIESL
                     KGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKRYND
                     LYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEEHEI
                     IKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQHIE
                     LKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDENLDIDRKFLESLKRE
                     IRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFEIKF
                     EEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGGEKA
                     LTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHRRGT
                     MEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
BASE COUNT         7656 a         4052 c         2538 g         9633 t
ORIGIN      
        1 aatataagta catattgttc tcttttgtta taatatcttc tcttattatt agtttagata
       61 aaaatatata tttggcactg gagtcaagct ctatattgct aattataact gtactttcta
      121 tatatataga aaatgagaat ttatcaaaat tatacagtca aaatctttat gataagctta
      181 gaatttctaa agatgaatta aaaaaagtta atgctgattt ggaaacttat gcaagttcta
      241 tagaagaatt agcaatttta aaagaaagaa atcgaatatc aagagaaata catgatagtg
      301 taggacattc tctttctaca acaataatac aattaaatgc tatagaaaaa ctcttaaaag
      361 acaaacctct aatttatgac ttagtacatg aacttagaga atttgtaact gaaagttttc
      421 aagatgtaag aagggctata tctgagttaa aacctgttga atatgaaaat taccaaagtt
      481 tatttaaaat caaagaatta gttaaaagct ttattaagct tacaaatatt aatgttaaat
      541 taactatttc aaaaaatact tggaacttat ccagaaatca atctatagct ttatatagac
      601 tcatacagga atccctttcc aactcatcta ggcatggaaa ggcaactgaa atcagaattt
      661 ttattacatt caatacttca aatcttataa ttactattag tgataatggt ataggatgtg
      721 gcaatataaa aaaaggaaat ggacttaata gtatcaatga gagaatatat gaattaaatg
      781 gtaaagttga atttgataat tctaataatg gtttcacaat tagagcttct tttcctaaat
      841 tttcaggggg tgattttttt gaataaaatt aaagttctta tagtagatga cgaaaaatta
      901 attagaaaag gtcttaaaat tatattatca tcttataatg atttagaaat tgtaggagat
      961 gcttctaatg gatatgaagc tttagaattt tgtaaaatga atgatgtaga catagttctt
     1021 atggatatac gaatgaaagt atgtgatggg gttctaggta caaggcttat aaaggaatat
     1081 aataattcta taacattatt aattttaaca acttttaatg atgatgaata tataaaagat
     1141 gctatgaagt ttggtgcttc aggatacctt ttaaaagata gctctgatga agtattgcat
     1201 gaagggattc gttcttcatt ttttggcaat attgtgcttg ataaaagtgt agctgaaaaa
     1261 atcatgacct ctgaaaaaac ggttaaacaa gagcatcttt atgacatgta caatttaaca
     1321 gaaaaagaaa tatctataat tagactaatt gcaaatggac ttaataataa agaaataagt
     1381 caagaactat tcttatctga aggtacaata aagaataaca taactaatat tttagctaaa
     1441 ctagaacttc gtgacagaac tcaactagca atctttgctt tcaaaaataa aattgtaata
     1501 gaataaatct aaaaatataa agtgacttaa gtcacttttt ttagtgactt atagtaatag
     1561 aattataatt cacaattctt tattataata ttatagcttt ttaacttata caaaattatt
     1621 ttggagggat tactatggat atagtcagag taaataatat aacaaaaaga tttaatgata
     1681 aattagtact tgataacatc agcttttctg ttaaaaaagg tgagatattt ggacttattg
     1741 gcccaaatgg tgcaggtaaa tctacactta taaatataat tacaaatctt atgttaccaa
     1801 atagtggtag tattcaaatc aatggtttag atttatcaaa agattatata aaagcaaagt
     1861 ctataatagg gttagttcca caagaattag caattataga aactcttact ccttttgata
     1921 acttagagta ctttggagct ttctacggtt taaagggaaa actacttaaa gaaagaatca
     1981 ttgaagcatt agaagttaca ggtcttactg aagtcaaaaa gaaaaaggtc aaaaaattat
     2041 ctggtggtat gcaaaggaga ttaaatattg gaatagcact cttaaatcat cctaaaatat
     2101 taatattgga tgaaccaact gtaggtgtag acccccaatc aagaaatcat attttcaatt
     2161 ttataaaaga tatatctaaa aaacatgaaa ctactgtaat atatacttcc cattatatgg
     2221 aagaagttga acacctttgt tctaaaattt ttattatgga tgaaggtaaa gaaattgctt
     2281 ttggagataa tgattattta aaatcactcg tatctacaaa tacaaaattg attatggaaa
     2341 taaaaaatat aaatgcccaa cttatctttg atttaaaaaa tactaaaggt gttatatctg
     2401 ttttagaaaa taattcatta ttagaattgg atatagataa aaaattacaa cttacagata
     2461 tactctctgt tattgacaaa aacaattcaa aaataatgaa aatttcttat gaagaaccta
     2521 gcctagaaga cgtattttta aatctaacag gaaaaaattt aagggactaa tggaggtgat
     2581 tttatgaaat tatacatgag tgtaaaaact atgctaaaga gtttaaaaag ctcctttata
     2641 cttaatttaa tatatttttt agctttgcct ctgattttat cttggtttct tgggatggtt
     2701 acagaaagca tgtttcaaaa ccctataaaa acagaatcta cccccattgt tatatatgac
     2761 aaagataaca caagattatc aaatgatttg acaaagtatt tgaaaaatga tttatcttat
     2821 atattaacag ttaaaaaaga tgattctaag gcagaattaa agcttactat acctaaaggc
     2881 tatgagagta gtttattaaa tgaaaaatca aatactctaa acatagaaaa acttggaact
     2941 cgtgatgata ttgcaatatt gcttcaagat atattagata cttaccatga aaaattttat
     3001 ttaaataatt ctcagaaaat aagttcagaa gatttttcta aattatttaa taaaaattct
     3061 attgatactt ctataataaa taacaatgtt aaacagagct cttatgaata ctttgcttta
     3121 gtttcactag gatttcttgt aataattttt ataatgaaca atattttatc aaattatata
     3181 agtgaatcaa agggactttc aaaaagactt tattctatgc ctataactag agtacagttc
     3241 ttaatttatg actttgtagg tttatggatt tattcattta tattcttatt attatatgtt
     3301 ttattcttta gaatacttgg aataacattt aaaggtaatt ttgccatatt gctcctactt
     3361 tgtgctttat catcttattt tatgacttca atatctacct ttgtaaccag cttttttagt
     3421 aaaaaatacg gtacagcaat agtttatgca ttactctttt tacagacaat ttttggaggt
     3481 atcttcagta tgataagtga tacatttact aagcttacaa gtttatctcc tacctattta
     3541 ataggagaat tgtttagtaa ttatgaaaca tttaaaacta tagattcaat aggagattta
     3601 attttcacat gtttaattat ctctacaata ttaattgcac ttgctattgt aaaggaaaaa
     3661 tataaatgga gggaggttta ataatgatta gattaactat tgcaaatata aaaagatatc
     3721 taaaaaatca tactctttta attaatatgg ttatgcttcc tattatacta attttttcac
     3781 ttaatttttt tatcaacaac tcaggaaatc aatcaatgta cttttctcca gtagcaattg
     3841 tatctgactc ttcaggaaag tatgaacata agttaataaa tagttctaaa ttaaaagaaa
     3901 attcatttag attaaatgaa caagataagg ctatgaatct attaaaaaat aataaggttt
     3961 ctgctgtatt cgttttagat aaaaattttt caaatagtat agataaatta caacgacctg
     4021 tagttaaatg ctttaaaatt gaaaatggtg gtggtagtct ttgggcagaa tcacaaatag
     4081 aatcttttat tactaaatcg ttaaaattga aagtggataa aaatatagat gataaattga
     4141 caaagacaaa tataattgat aacaaaccag ataagaataa aggttcattt ttagtagtct
     4201 tcttgatatg ctattttatg tatattaatg cggcacatct tgcttctgat ttatttacat
     4261 taaaaaaatc aaatgtgcta aaaagactta tctctacaga taataaagat ataaaaataa
     4321 ttttcagtat atttttagga ctatttttta ttcaatcaat tgtatacact tttgctctat
     4381 tatgtttttc aattatagaa gactttaatt tgagtctgaa tgtattgatg attgtactag
     4441 caaatagttt tgtttccact ggatttgtat tttgggtagc tagagtattt aaaaatgaaa
     4501 gttctataag tcttatatct acattttatt ctttaatagg tctagctata tctatctcta
     4561 gtctaatacc atcaatggat aaattatcct ttatgactaa tctttcaaag ttcacaccat
     4621 tttattggac tatagatgct attaaaaaca atggtagtat tttaataaat ataatagctc
     4681 taatattaat tggaattata tttgtaactg caggaagtct taaactaaga gattttgcta
     4741 aaaactaata attattaaat ataattagta tctattttta tataattgga aaagaatatt
     4801 tcaacatatt aaattatttt atcttatatt tttctcttta gtttcacaca tcaccaagtc
     4861 taaactttat attatatatt aatatttttg acttgtcaag ttatttatgt tataatatta
     4921 atcattagat aattaaagca ttgtacctaa gttgcaatat ctaaaattca atttggaggt
     4981 ataactagca tatgtataaa attggtgaaa gtgtaatgta tccaaaagag ggagcctgct
     5041 ctgtaaatga tattgtaaca aagaaaataa atcatgagat gcaaaaatac tatgaattaa
     5101 gtgtcatttt taatagtaac cttaaaattt cgattccagt tctaaatgca gatagaattg
     5161 gcatacgtcc agttatggat ggaaatgatg ttgataattt tatccaatct attaataaaa
     5221 cagatggtgt atggattttt gatagaaaag aaagacttaa actgtaccaa gataaatttc
     5281 attcaggaga tgtttttgaa attgtaaaat taatcaaaat gcttatgata caagacagtt
     5341 caaaacaatt gtgtagcaca gataaggagt ttttaaataa agctcaaaaa tttgctttat
     5401 cagaattagc tgctgctcaa tgtaaatcct atacaatggt attagaggaa atgaaaaaac
     5461 atatattaaa ttcaaagaat acaaattaaa ccagtttttt aaactggttt tattttttat
     5521 actaatcatc catgctactt tagcttattt taaactgcct aatctaatat taataaagtt
     5581 atctcaatta gatagatgta ttttattcaa ataaaaaaaa ctaagagtaa atcatattac
     5641 tgatttactc ttagctaata aaatttaatc ttcttcaagt tcttttttct cttgtaataa
     5701 tacacttaat tcatttgctt ctaaaacttg tgcctctgca atatcaagta actcttgttg
     5761 ccattccaca catttatctt tgtaatcaaa aggtagcgtt ctgtcaacta tgtacttatc
     5821 aatacagtcc tccgcacttt taattatttc ttttctttca tcaataaatt tttctaattc
     5881 tactaaggct tcttcataag cttttctact catataaatt ccccctttgt acaattattc
     5941 tacattaaaa tgatttttcc tcttttttgt ataaaatttt atttgtatat aacttttcca
     6001 tcaatatctt ttatagtttg acatccagtt aatatcatag aactacttag ctctgattga
     6061 agtttattta cataagtttc tacaccatca gttgcaccac caaaagaagc agtcacaaaa
     6121 ggtcttccta ttaatactgc atctgcacct aaacctatca tttttagtac gtctaaacca
     6181 gttctcactc caccatctgc aagtattgta actttacctt taacagcatc agcaattttt
     6241 ggtaaaactt cacatgctcc tggtgtacag tcaagcactc ttcctccatg atttgataca
     6301 actattgcat ccacacctgc ttctactgcc attaaagcat cttcaacagt cattatacct
     6361 ttcaatataa atggtagttt agtagacttt actaactcct ttatttgttt aacattttta
     6421 ggaagtactg gttttccatg taatgataaa gttactagac cacaggcatc tatatcaact
     6481 ccaactgcaa atgcaccagc ttcttcagct aatcttatct tttttataat attttcatta
     6541 tcccaaggtt taataaatac aattccagct ccattatact ttttgactac atctaaattt
     6601 tccattaaaa aagcatctac tgccgtatca ccaaccattg cataaatacc actattagca
     6661 catcctgcaa ctactggttc tatgtaatct ctttcattaa tttttccacc catatttaaa
     6721 gtagttcctg ttactggagc tgcaaatata ggtgcactca ttttctttcc aaacatctct
     6781 atagatgtat caggatttga tacatcatgt attactctca tatttacttt tactttttct
     6841 aaactcttgc tattttctat aaaagaagaa ccacttcctt tacctcccat gccaggcact
     6901 tcacctgcac aagcaatccc attacaaacc ttacaaactt tacaacttcc atttaaattt
     6961 tctctagcac tttttaataa ttcattatat tccatcttta atcccccatt aactatagta
     7021 atttatatta tatatattat atcatattat atttacagta tatttttcaa aaaacttttt
     7081 ctgtggatag gagttatgcc atatttttca atagcttcat agtgttcttt agttccatat
     7141 cctttgtgag atttaaaccc atattctggg tatactctat catattggta cattatacta
     7201 tccctagtaa ctttagcaag tatacttgct gctgctattg atatagattt tgaatctcct
     7261 ttcacaattg gattttgaga tatgtcaata cctggtattg ttgctgcatc aactaataaa
     7321 taatctggtg ctttttttaa acaatttata gcctttttca ttgccatata tgtagcattt
     7381 aatatattaa attcatctat ttcttcatta tttactatac ctattccata atctagtgct
     7441 tcttctttta ttacttcaaa aagttcatct ctttttgcct cactcagttt cttagagtca
     7501 tttacacctt ctattttggt atctttttta aatactacaa cagaagctac aacaggtcca
     7561 gcaagtggcc ctcttcccgc ctcatcaatt cctccaatat ataaataacc tttatcatag
     7621 ccttcattct caaatatatt tatagtttcc aatctttctt cttcttttct aatattatcc
     7681 agcttttttg ctagttttat agctagacct tgtacagatt ttctttcatc aactcttaac
     7741 agctctatat attccatata tttttctact tctaaagtct ctattatttc tttaatctcc
     7801 ctcacacttt tatcctgcat accattccct catctttcgt ttttaaaaat ttaatttttt
     7861 aatatattaa aattttttaa ttagagttta attgcatcca ctatagccac attttaaaca
     7921 tatactacat ccacctgtat gtgcaattcc ttcacttcca cactcagggc acacaaattt
     7981 ttcatcttct tcaaaatttt tatttattat ttctttggct ttttcatctt tattatcttt
     8041 ttctttttta ttatttttat aatattcttt tttactattt tcttttttat cttctttatt
     8101 attttcttcc tttttttcat ttattaaaat tccactcctt ttacatccat ctctaaatat
     8161 tgttactcct ttaagaccag cctcccacgc cttaatatat atattgaaaa catcttcaac
     8221 tgtagtttca aaaggtatat ttattgtaga tgatatagaa gcatcaatat acttttgcca
     8281 tactttttgc atgtttattc tttcttcata tcctatattc atagcagtaa caaaaaaatc
     8341 tggtaaacat tcttcatctg taataccttt cttgtccatg tactctttaa caattggagt
     8401 atatacttta taatacacat cctcatcatg caagctttca gtttttctta tatatgaaag
     8461 attaaatata ggttctattc caccactgat acctatcatt gtagatatgg aacctgtagg
     8521 aggtatggtt aaaagttgtg aatttctaag cccatacttt ttaaccattt ccttagtgtc
     8581 ttcatttaga ttttctataa aaaacttaga tttagaaata ttttcatatt tatactcact
     8641 aaatgttcca tattctttag caattaatgc tgattgcttc acagcttcat ttaacatagt
     8701 cttaccaatt aaatcacata gttctaaaga ttcatcagaa ccatatctta ttcccatttt
     8761 tataagcata tcagctatac ccattacacc taaacctatc tgtctatact tatgtacact
     8821 atctctttgt tcttgtaatg gatgcaagtt caatccctca tctaagacat catttaaagc
     8881 tactacagct tctctaacgc aagattttaa tttattaata tcaaaagtag catgttcacc
     8941 aaatggttgt attataaact ctgacaagtt tattgagcca agtagacaac ttcctccact
     9001 tggaagtggt tcttctgcac aaggatttac tcctgaaaag caaaagttct tatcttcact
     9061 cataaaatta tatgttttta ttttatccca aaacaatata cctggttctg cataatccca
     9121 gttatttttc acaaatttat taaataaatc ataagcattt actatcttaa ctattttttc
     9181 tccagtagtt tcaacttcaa aagtacaatt atataacttt ttttctctta cagcttgcat
     9241 aaattcatct gttactctta cagaaatatt tgctttagta accttctcca aatctgtttt
     9301 tatatctata aagtcttcta tctctggatg atttacatcc atagaaatca taagagctcc
     9361 tcttctccct ctttgaccaa ttaagccagt tgtcatactg taaagttcca taaaagagac
     9421 tgctccagtc gtatgttttg cagcattgtt aactttcgct ccttttggtc ttagctttga
     9481 aatatcaatt ccaactcctc caccataact aaaagttcta gcaagttttt ttgcagtatc
     9541 aaatatatct tctatgctat cttttggtgg ttctattaca taacaattag aatatgttac
     9601 tttttttccc tctttctgta atcctctatt tgctaaaatt cttccagcaa atagaaatct
     9661 tttttgtctt attagttttg atattcttga actattattt gaaattctct ttatccattc
     9721 atcaaaactc tcaccattat gtctatactt gttcttccat attgattttt gtaattcatc
     9781 aaactcccaa gctttagtcc ttatttcaga gcgtctttct ctatataata tgtagtgttt
     9841 tgctatatct tttctatttg attccataag tagtacttca actatatctt gtatttcttc
     9901 tacggataag catttttcca tagaattata gtcattagct atttttcttg atatatcata
     9961 tgccaactct ctatctactc caccttcact atttatacta gctttataga cagcatcttc
    10021 aatcttactt ttactaaaaa gttcttttgt accatctctt tttattatgt atttcatttt
    10081 taaacctcca ataaattagt attaaattaa tacacacatt aactataact ctaaacaaac
    10141 tttttatata tttgtatatt ttcatattaa ttatctaaca taatatatat tatactattt
    10201 tatattcaat ataacactcc ttatagtttt cttaacttgt aaaatatctt cctaaaaaac
    10261 tcaaaaataa tataaaaaag tatataaaag tcaaattata ctcttatata ctttattttt
    10321 ttatattttt ttcattttaa ctttgattaa ttaataagta tttagaaaat aaattcttta
    10381 ttttttcttt acaaaaatat gtattgatgt ttttatatta atactaaaca tttataatat
    10441 ataatttaat tttatttata attataaatg aatctttttt attttattat ttttataaat
    10501 catactactt caaaaataaa tttttaaatt tatcaaatag gattaataat gttcttttat
    10561 ctacaataat ttaataattc ttttaaatat aaaaaggaat tgcctatata atttaaaggc
    10621 aattccataa ttatcaatta gtttttatta ttatgcagtt ttactgcttt tagatggaat
    10681 aaagtttcct attattcctg ctattacaac tggaactatc cagttaaatc ctaatgaagc
    10741 aaatggtaag ctattaacta gaggaatttt tataccaaaa cttgttgcaa ctgttaatac
    10801 acttactaat aatgccatgt atgcagcaca tttgaacacg ttgtcatttt taattttatt
    10861 actaaataat gctagtataa ctagagttat agttgctgga tataccatac ttagtatagg
    10921 agaagagaat tgtattattg tacttactcc aaagtttgat atgattgcac taaatacaca
    10981 aactactata actatatgct catactttaa ttttccatct gtaagtgttg agaaatattg
    11041 accagctgct gaagaaagac ctatagctgt tgttaaacat gctaatgcaa ctataatagc
    11101 caataaaatt ttacctgtag ttccaagtaa agctgctgtt attgcaacta ttaaagctgt
    11161 ttgttgaaca tcttgtccat attgttgaga cacagttgct ccaagataac ataatccacc
    11221 ataaactaat gccattccta ttactgcaat tacacctgca cttattgtgg ctttcatctt
    11281 ttctttctca cctgtataac ctttagctat tactgacatg attataattg atgcaaatac
    11341 actagctgcc aatgcatcca ttgtttgata accttgagtt ataccttctg caaatacatt
    11401 ttgtattaaa gaactgtctc ttatttctcc taatggagat acgatacctt taactattaa
    11461 tactgctaaa gctataagta aagctggagt taatattgac ccaactatat ctacaacttt
    11521 tgatggtctt attgttaaaa ccaatactag agcaaagaat actatagaga atattactgg
    11581 gcttattcca gaacctattg taggtaatat acccatttca taagttgttg ctgctgttct
    11641 aggtattgct aaaagtggcc ctatacagat taccattgca catcctaatg caatacttaa
    11701 tcctttgcct gctcttgaga acatcttcga tgtgtctcca ttgaacttag ttgctgctat
    11761 aactgctaat aatgccaaac caccatctgc aaaaaggaat cctatgaaag ctactagcca
    11821 actacttcca gataaaactc ctagatatgg agggaagatt aagttccctg caccaaaaaa
    11881 cattgcaaat agtgcaaatc caattacaat tacatcttta aaattgattt gtttctcacc
    11941 catttaaagc acccccattt gaattttact accttttact aaaaaataag tccaatctct
    12001 taattaaatg aaaacctttt gacgagattt tatttaatta tacatttttg acttaaattt
    12061 gtcaattatg tttcataatt tataaaatct tcacaatatt taatacaact ttcttaatta
    12121 aacaaaatca acctgtatac tttaaacata gttggttttt tgttttttct ctaatttttc
    12181 ttgataaaat taactattcc gaataattaa aatattaaga ctttttagat tattcgattt
    12241 attattaagt tgtattgctt tatatactgt atatatcact ctcctttttt acattcatat
    12301 aatcttttta attcaattta aattttaaat attttgtgtt tattatataa tctgaaaaaa
    12361 aagcagtcaa tagcattttt aattttttta attttcaaaa ttatgattct taaaaaatcg
    12421 ttttcctttt atcataacac ctatttacgt taattcttgt agtattttgt atttattttg
    12481 ctaaattgac agttaacttt attcaatttt tattctactt acgtaaattt gcctcttgtt
    12541 ttttactctt aaaaccattt tttctgaaaa ttccttatta tgatttatca acttattttt
    12601 cttcataaca attactctct aacttccaac ttacttaaac tttgcagttg ctagtattca
    12661 cgtttacata cttatatgtc ataattaact aaaaattctt aatatatctc tcaatgaaaa
    12721 caatttactc atttatttaa tacatttata taatcatatg tcttaaattt tgttttatta
    12781 ttttattatt gtcacaattt tatttatatt atatttttgt aaaaatcatt taatatgtat
    12841 acttaaattt ataaaattac tctaaaattc ttttttaatc tctattattg ttaaaaaata
    12901 aactatatat ttttttgata ttttcttata ctttttccat attaaataca aataattaaa
    12961 tatagaatct aaaaataaaa ggagttattt gtacaaataa ctccttttac ttttagttaa
    13021 ctcatttatt tacaattgat tatattttaa ttaaacaaaa cttagtttgt tccaagtgta
    13081 ttagattgac tctttgatgg tataaaatta ccaattattc cagctattat aactggcacc
    13141 acccagttaa atcctaatga attaagaggt aaagaattta ctactggaac agctactcca
    13201 taactagata taactgttag tatacttaca agcaatgaca tatatactgc tcctttgtat
    13261 acattatcat tcttaatttt ttcattgaag aaagctaaaa ttattaaaac aattgatggt
    13321 ggataaacta tacttagtat aggagatgct atctttatta tagttccaac accaaaagat
    13381 gctactactg cactgaatac agatacagct aatactattt tttcataact caatttacct
    13441 tttgtaagtc tagagaaata ttgacctgtg gcagatgtaa gacctataga tgtagttaaa
    13501 catgctaatg atactactac tgctaaaatc gctttcccaa catttccaag caatccttca
    13561 gttatattta ctattacttg tgattgtact gcatctgttc catacattgt tgatacagtt
    13621 gccccaagga agcataatcc tccataaact agagctaatc ctccacaagc aagaacaccc
    13681 gccttaccaa tcattttcaa cttgtcacta atagtagaat atcctttatc atttaaagat
    13741 actattagca ctgatgcaag tgctattgct gcaaaagcat ccattgtctg atatccttga
    13801 cctatacctt ctgcaaatac attaggtatc ataggtttat ctactatatc tccaagaggt
    13861 gatataatac cttttataat tataaatgct aaagctatta gaagagctgg agttaaaaac
    13921 tgtccaacta tatctacgac cttagaaggt cttattgtta gtacatatga aatcgcaaaa
    13981 aaaagtatac agaataataa cactggaatt gaagttccaa ataaaggcat tatacccatt
    14041 tcataagttg ttgcacctgt tcttggtata gctaagaatg gtcctataca taaaatatct
    14101 gcacaaccta taagaatccc taacttcata ccacatcttt taaacatttc aactacgttt
    14161 ccatcgaatt tagctgtagc cattactgct agaagtgcca atccagcatc agcaaacgta
    14221 aatcctaaga aggcaattaa ccattctgga cctgtaatta ttcccaagta aggtggaaat
    14281 attaagttac ctgctccaaa gaacattgca aataacgcaa atccaaatac tataacatcc
    14341 ttggtcttac ccattataaa atcccccttt ttaaccttat taaattaata aaatgtctcg
    14401 attgtttacg cttgcataag taagttgaat taaacaataa gaacttatta ttaaattaat
    14461 aaaattaaat aaattaaatt tttaatatat tgtatttatt tgtgcttatt atatattata
    14521 cgaaacaagc aagtcaatat gctaaaattt taaataatca cactcatttt aattttcaaa
    14581 atattaggta tatttgtctt aaattaatat ttttaaaggt tttctaacct aatttatact
    14641 tttatatgga gatatttgtc tatatttcaa aaaaataaaa aagcctttgc taaaaggctt
    14701 ttttaaattt ttaacattaa atttttgatt ttgttttaaa atctatcttt taacgttttc
    14761 tggaacttcc aatgttatat ttcctatttt tccatctcta aattcattta atacagttgt
    14821 ggctatgcgt gtataatcta gttctttttt acctgttata aaccctcttt tatggccaat
    14881 catatccata gtttcaattg gagtttctcc tagacaatct aacttatatc tggctttcaa
    14941 cttctcaggt tctattttca taagtttttc tataagtctt aaagccaaag tttcagcatc
    15001 taaaatctca tcctttatag ctctactaaa tgctaaattt aatgcaactt cttggtcttc
    15061 aaacttaggc caaagtattc caggtgtatc taaaagttca agatttccct ttaatctaac
    15121 ccattgtttc cctttcgtta ctcctggctt atctccagtt tgagtgcttt ttctacctgt
    15181 taatttgttt ataagagacg atttaccaac gtttggaact ccaactatca ttattcgtat
    15241 agctctttct tttctccctt tgtcttttaa agaactcatt ttttctctag ttacattttt
    15301 acattcttcg attatcttat ttataccaac gccttttatt gtatctactg gtatagcttt
    15361 gatattaatt ttcttatagt attcaatcca ttgattcaat ttatccctat ctgccatatc
    15421 actcttatta agtacgacaa ctcttggctt atctcctaca agcctgtcta tgtctggatt
    15481 tttactacta aacgggattc tagcatccaa aagttcaatt actacatcaa tcaattttaa
    15541 gttatttttt actaactcct tagttttttt catatgacct ggataccagt ttatatgtag
    15601 attgtcattc ataagatact cttcgtattc atttgacaca tgtatcactc cttattaata
    15661 ttatattatt atatcctaat tccactaaaa aaatctatct taacaaacta taatattgtc
    15721 atctttttaa cgtcatactt tacataatac tgttctctta tttttaatat tgttacaaaa
    15781 tataatgcaa tatttaccaa ttttattttt cattttaaaa gctataaatt catagataaa
    15841 taatgtatat tttcaacaaa tatttctatt tatttctagt ataattattt gctgtaattt
    15901 tcattaaaat agaaagagga ctgataaatc agccccccat ttataagtaa agtttttaat
    15961 tatttatttc tagcttcttt tatcttagca gctttaccta ctctacctct taagtagttt
    16021 agtttagctc ttcttacttt accttttcta gtaacttcta ttttttctat ttttggagag
    16081 tgaactggga aagttctttc tacaccaaca ttgaaagaca tttttctaac tgtgaaagtt
    16141 tctcttgctc ctccaccttg tctctttaat actacacctt cgaatacttg tattctttct
    16201 ctttttcctt ctataattct aacgtgtact ttaactgtgt ccccaggtcc aaaattagga
    16261 acttcatttt ttaattgttc ttgctcaatt gctcttagca tttcattcat ctttcttcct
    16321 cctagatatc atagacgttc ttaactaccc gaccagtgta aacagaggaa cgcccgtatt
    16381 ttcaacattt tatattatac tatacttcaa tagttattac aagcactttt atgtttttaa
    16441 ttccatttat aggtacttta ttgtatacat atatattaat ttttcattat atttttattt
    16501 ttcattagac tttttatata aatcaaatcg tctttctttg gttatcctta tagattcttc
    16561 tcttctccac tcatctatct tcttatgatt ccctgataaa agcacttctg gtacttttaa
    16621 tccttcaaaa tctctaggtc tagtgtaatg aggatattcc aataagttat ctttaaatga
    16681 ttcttcttca aatgattctt cttggtttaa tacacctggt attaatctcg atatagaatc
    16741 tatcattata agtgctggga gctctccccc agttaataca taatctccaa ttgaaatttc
    16801 atcagtaact attaaatcaa tgattctctc atctattcct tcataatgac cacatagtag
    16861 tattatatct tcttttaaag acatctgctt tgccatagat tgattgtata ccttaccttt
    16921 tggagtaaga taaattacac ttgggttatt tatattatga gttgttatta tatgcttata
    16981 tgtgtcatat ataggttgag gagtcattac catccccgct cctcctccaa atggataatc
    17041 atctactttt ttatgtttat tattagaaaa atcccttata ttatatatat gaacctcaat
    17101 tatacctttt tcaactgctc tcttcattat actttcatcc atgtacgaat taaatatttc
    17161 tggaaaaagt gtcattatat gaaatctcat attaccacct aatctatcat tcccttaata
    17221 gggtctataa tcatttttct ttcatcaata tctattgtag gtacaaattt ttttatagct
    17281 ggtatcataa attctttatc ttcctcacct tttactacat agacatcatt tgctgagtat
    17341 tgaagaacat cttctagtat tcctacatat tttccatcta cagttaaaac ttccattcca
    17401 atcatatctg ctataaaaaa ttcgccttct tcaagctctc tgctatcttc tctagataca
    17461 tacataaatt tattttttag tttttctgct ttctctatgc tgtctatgcc ttttatcttc
    17521 attataacca tagaaccttt gtatcttact ttttcaacag ccaatttatt atttaaatct
    17581 tttcccagat agaaatcttt taattcatca aacctctcta tatcatcagt aagtggataa
    17641 actcttactt caccttttaa accttgtgta tttactattt gacctacctt aaaatgagtt
    17701 aatttttctt tcatgttatc accttcttaa aaaatttaat cttatgtggt catatcatca
    17761 taaaatctta aactacgcat ttatataaaa aggactaggc attataccta atcctcctat
    17821 tttatactat ctcaagagaa acttttatat tttctctatt tgcaacagat cttacgacag
    17881 ttcttatagc tttagctatt cttccctgct tcccaataac cttacccata tcctcttgag
    17941 caactgtaag ctttaagacg ataccatcat tatcttcaaa ttcctcaaca acaactgagt
    18001 caggattatc aactagagcc ttagctatat ctacaactag ctctttcata tatttcatct
    18061 cctaaagtaa ccttagcaat gagcccttac ttaaactaat tgccaagaaa aaattatttt
    18121 gcttgtttag aagcttcgaa tttttctatt actccgtttt ttacaagtaa ttttttaact
    18181 acttctgttg gctgagcacc agtagctaac cattttatag ctttttcatc atttattctt
    18241 acttgtttag gttcagaaat tggattatag tatcctattt cttctataaa ttttccatct
    18301 cttggagctc ttgaatcagc tactactatt ctgtagaaag gttttttgtt agctcccatt
    18361 ctttttaatc ttattttaac tgccattaca gtcacctccg aataattttt acttttttat
    18421 attttattta aaaaaaggta aaccgcctaa gccgcccctt ttcttcatac tcttttgtga
    18481 accagcaaac atcttcatca tttttttcat ttcattaagt tgttttataa gtctatttac
    18541 atcttgtaca ctagttccac tgcctttagc tattcttttc tttcttgaag catttaatac
    18601 tcctgggttt cttctctcat atgtagtcat tgactgaatt atggcttttg ttctcttcat
    18661 ttctttgcca ttcaaatcta catctccaag ttggtctttt acatttccca taccaggtat
    18721 cataccaagt atcttgtcaa gaggtcccat attttgtatt tgttccattt gttgtaagaa
    18781 atcttcaaaa tcaagctctt gttttttaat tttttgctct aattctttag ctttctctaa
    18841 gtctatattt tcttgtgctt tttctattaa acttaagaca tctcccatac ctaatattct
    18901 tgatgccatt ctatctgggt ggaaaggttc tatatcatct agcttttctc ccatccccat
    18961 aaattttata ggcttttgtg taactgctct tattgaaagt gcagcaccac ctctagtatc
    19021 tccatccaat ttagttaata ctactccatc aacaccaagt gcctcattga agctttctgc
    19081 aacatttaca gcatcttgac ctgtcataga atctacaacc aaaagtatct catgtggctt
    19141 aacttctgat ttaatagact ttaactcatc cataagtact tcatctatat gaagtctacc
    19201 agctgtatct ataataacta aatcattagc atttttaatc gcatggctta aacctgcttt
    19261 cgcaatattt actggatttt ctttatctcc catattgaat acaggtatat ccaatttttc
    19321 tccaacaact tgaagttgct ttatagctgc tggtctataa atatcacaag ctactaatag
    19381 aggtttttta ccttgctttt taaaatatcc tccaagtttt cctgctgtag tagtcttacc
    19441 tgcaccttgc aatccaacca tcattaaaat tgtaggaggc tttgaggaaa tcattacttt
    19501 actttgtaca tctcccatta aacttgtaag ctcttcattt acaattttga ttacatgctg
    19561 agctggagtt aagctttgca taacttcttg cccaacacat ctctcttgaa ctttttttat
    19621 gaaatcttta actactttaa agttaacatc tgcctcaaga agagcaagtt taacttctct
    19681 catagcattt ttcacatcta cttctgtaag ttttccttta gattttaact tactaaatgc
    19741 cccttgtagt ttatcagaca atccttcaaa tatcatttta tcatctccct acatacatct
    19801 tctatatttt ctagcttagg gattaaatta gcacaatctc tattgtgcaa taaatcttct
    19861 ttaatgtcaa taattttatc ttttataatc ttaatatttt tttcctgctc ttgaatcttt
    19921 gatactaagt gtaacttttc ttcataatct cttagtattt tttctgaacg ctttaaggta
    19981 tcataaacac cttgtcttga tacattcaga ttttcactaa tttcacctaa agaataatct
    20041 tcttcatagt atagagcaac tatttctttc tgcttgtcag ttaataattc tttatactgt
    20101 tcaaataaca atccaatttc gaccattttt tctatattca tatcttacac ttcctagcag
    20161 tatactgtaa aggttattta ctttacacta ttgtatttta tatcataaca acactcttgt
    20221 caaccattat ttttaaaaga acattagtta ccaaataatg catctgaaaa tgattttgca
    20281 ttgaaatctt gtaggtcttc tacactttct ccaactccaa taagttttac aggtacatct
    20341 acttctgatt ttactgcaag gactactcca ccttttgcag ttccatcaag ttttgtaagt
    20401 actatacctg ttatatctgc aacttcttta aatgtctttg cttgaacaac tgcattttga
    20461 cctgttgtag catccaccac aagaagtact tcacgttttg cttctggaaa ttctctatct
    20521 actattttaa atacttttcc aagttcattc ataagattag ccttattgtg taatcttcct
    20581 gctgtatcac atattaatac atctgttttt ctagcttttg cagcttttat agcatcaaat
    20641 actacagctc cagggtctgc tccctcttga tgttttatta tgtctacatt ggttctattt
    20701 gcccaaattt ctaattgctc tgtcgctgct gctctaaatg tatctgctgc tgctaataaa
    20761 acttttttac catctttttt gtatctattt gctagtttac ctattgtagt agtcttaccg
    20821 accccattta cacccaccat taatattata catggtgctg gttctatatc tagtgtagag
    20881 ttttcatttg taagaatatc ttcaactata gatttaagtt cttctcttac ctttattggt
    20941 tcagtaatac ctttttgctt tattttatct cttagtcttt caattatatc catagttgta
    21001 tttacaccaa catctgctgt tattaaaatt tcctctaaat cttcaagtaa ttcttcatct
    21061 atctttgtat atgattttaa aacttcatct attctatcag ttattccttg ctttgctttt
    21121 gtcaatcctt gttttagtct ttcaaacaag ttaactttct tatcttcttt atcttctatc
    21181 tctttagact caatttcatc ataattttct aattcttcga ttatctcttc ttgagaatca
    21241 ttatttgaaa tattttctac ttcttttcca ttactatcca tctcaacttc tattttttca
    21301 aagttttcga tttcttcagt gccttcatta ttgacacttt cctcattttt ttcttcaaca
    21361 tcttccactt tatctatcac ttcttcttca agtcctgaaa aaatagtttc ttccaagttt
    21421 tctaaattat caacactgtc ttcaacttct atttcttctt cagcatcttt tttttctatt
    21481 tccttttcct tgtcttttcc aaaaccaaat aattttttta acactgttat tcctcctatg
    21541 tcaatctaag ttatataata tctgttattt cctgagcttc ttttaatttt aaactaataa
    21601 cttttgaaat ggctttttct tgcattgtaa ctccatagat ataatcagca gcttccatag
    21661 ttcctctcct atgagttact gatataaatt gagtctcttt agataaatcc ttcaaaaatt
    21721 ctccaaatct aaatatattt gcgtcatcaa gtggcgcttc aatctcatct aatatacaaa
    21781 atggtgttgg ctttgtaatc aatatagcaa ataatatact tattgccgtt aaagctttct
    21841 ctccaccaga taataggttt aaatttttca tttttttacc tgggggttga gctgttatta
    21901 gtatatcact ttctaataaa ttttctttat ctaaaatagt taattctcca caacctccac
    21961 caaataatct cttatataca tatttaaaat ttttacttat ttcttcaaac ttaatttcaa
    22021 attcagattt catattttct tctaaagtat gtataagttt ttctatctct tccatagact
    22081 cttctaaatc ttgcttttgt tcgctataaa aatcgtatct ttcttttatt tcctcatatt
    22141 cctttataga gtctatattt atatttccaa gacttcttat ttctctcttt agactttcta
    22201 agaattttct atctatatcc aaattttcat ctttaatttc caatgcttgt actaaggtca
    22261 tatcatattg ctcaaacaac ttatttatat atgtgtcttg actagttttt aatctttcta
    22321 atcttccacc aactttaaat aaactttctt taagttctat atgctgtcta tctatagttt
    22381 ttaattcttt attaatttca tcaaaactat tttttaaatc atcttttgct atttttctag
    22441 tttcaagatt tctattacta tctcctagtt gttttgttaa attttctttt tctttttctt
    22501 cagtgagtat agaatcttgt aatttaatta tttcatgttc ttcataattt aatgactctt
    22561 ctaattgttt atttttttct tctagctcac aattttcacc agatattctt tttatatctc
    22621 taactatact attgtaaact tctgttttct tcactaaact taagttcaat tcatcaaatt
    22681 cagatttttc tttatcatat aaatcattgt atctttttat ttcctcattc aatgcatcaa
    22741 ttttttcttt atttttattg tataaatcat ctaactcttc catatctttt ctaacatcat
    22801 cacttttttc aagtgtataa tttaggttag aatttaaatc attcttctca ttttctaatt
    22861 tagtaatact accttttaac gattcaattt cagactcaac attctttata cttgtacttt
    22921 ttattattat acttttttct aaatctttta ttttactttc atgtgaatca atttcatttt
    22981 tgatattttt cacatctttg tctaaagatt ctctttttaa ttctagatgt gaaatttcat
    23041 tcttgatatt acttatcttt tctgtatatt cattaatgta tctttttctc gatagtatat
    23101 tcccattagt ttttagactt cccccagtca aagaacctcc tggatttaag atttcaccat
    23161 ctaaagttac tattttaaac ctatgaccag tttcttttgc aaattttatg ccctcatcta
    23221 tattatttat aagtattgtt cttccaagta tattttcaat tatatttcta tacttttcat
    23281 caaatgtaat taaatcactt gctattccta tgaacttagt atttgctttt aaatttccta
    23341 gacttatttt atttgattta attatattta atggaagaaa tgttactcta cctaaattat
    23401 tctgttttag atagtttatt gcagacttag cactaaactc attatcagtt attatatttt
    23461 gcatataagc accaagagct gcttctatag atttctcata cttttcaggt acatttataa
    23521 tctgtcctaa tgctccatga actcctttta aatttttatt ttttagtact tcttttactc
    23581 ctctattaaa tccttcataa tgattttcca tatctatata gacatttaac tttgaattat
    23641 atccatttaa attatattta cttttctgta tttcatcttc tagtttattg tgttcactaa
    23701 ttgaatcctg caaattaatt gataattctt tatgtctatt atttacattc tttaaatttt
    23761 cattttgcat attaaattct ttatttatag tatctaattc agatgatttt atttcaatat
    23821 ttttgtttaa ctctgttatc tctgaattta tattttcatc tctgatattc atattttct
//
LOCUS       DAGQVA010000059        23402 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.059, whole genome shotgun sequence.
ACCESSION   DAGQVA010000059 DAGQVA010000000
VERSION     DAGQVA010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.059"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..696)
                     /locus_tag="MIV85_002636"
     CDS             complement(<1..696)
                     /locus_tag="MIV85_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBY2961965.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSI"
     gene            970..1644
                     /gene="fsa"
                     /locus_tag="MIV85_002637"
     CDS             970..1644
                     /gene="fsa"
                     /locus_tag="MIV85_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBY2961966.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(1766..3160)
                     /locus_tag="MIV85_002638"
     CDS             complement(1766..3160)
                     /locus_tag="MIV85_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBY2961967.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFTFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(3238..4584)
                     /locus_tag="MIV85_002639"
     CDS             complement(3238..4584)
                     /locus_tag="MIV85_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2961968.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      4834..4936
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            5030..6406
                     /locus_tag="MIV85_002640"
     CDS             5030..6406
                     /locus_tag="MIV85_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBY2961969.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(6520..7665)
                     /locus_tag="MIV85_002641"
     CDS             complement(6520..7665)
                     /locus_tag="MIV85_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBY2961970.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            7918..8625
                     /locus_tag="MIV85_002642"
     CDS             7918..8625
                     /locus_tag="MIV85_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961971.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            8672..10267
                     /locus_tag="MIV85_002643"
     CDS             8672..10267
                     /locus_tag="MIV85_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2961972.1"
                     /translation="MSNLSILIKNNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIGSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            10370..11452
                     /locus_tag="MIV85_002644"
     CDS             10370..11452
                     /locus_tag="MIV85_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBY2961973.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            11601..11762
                     /locus_tag="MIV85_002645"
     CDS             11601..11762
                     /locus_tag="MIV85_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBY2961974.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            12103..13371
                     /locus_tag="MIV85_002646"
     CDS             12103..13371
                     /locus_tag="MIV85_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBY2961975.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            13566..14354
                     /locus_tag="MIV85_002647"
     CDS             13566..14354
                     /locus_tag="MIV85_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBY2961976.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            14354..14803
                     /locus_tag="MIV85_002648"
     CDS             14354..14803
                     /locus_tag="MIV85_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBY2961977.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            14807..17071
                     /locus_tag="MIV85_002649"
     CDS             14807..17071
                     /locus_tag="MIV85_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBY2961978.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLIYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGRMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            17211..17522
                     /locus_tag="MIV85_002650"
     CDS             17211..17522
                     /locus_tag="MIV85_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961979.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            17808..18308
                     /locus_tag="MIV85_002651"
     CDS             17808..18308
                     /locus_tag="MIV85_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBY2961980.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            18365..19351
                     /locus_tag="MIV85_002652"
     CDS             18365..19351
                     /locus_tag="MIV85_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBY2961981.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSGKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            19401..20123
                     /locus_tag="MIV85_002653"
     CDS             19401..20123
                     /locus_tag="MIV85_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBY2961982.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            20152..22086
                     /locus_tag="MIV85_002654"
     CDS             20152..22086
                     /locus_tag="MIV85_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2961983.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLEIIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            22079..23347
                     /locus_tag="MIV85_002655"
     CDS             22079..23347
                     /locus_tag="MIV85_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBY2961984.1"
                     /translation="MSKNIYVKETYEWIRIGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIHIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
BASE COUNT         8989 a         2498 c         3793 g         8122 t
ORIGIN      
        1 tatagaacta atatcttcta aatgagcaaa cttgaaattt ccatcaaatt taaacttttt
       61 atcttccata actataaata cttttttact tgaatttatt atagccttct tcgtaagacc
      121 atcttcaatt tcaaaagttg taagtgaaga gttgaataca tctactccac aacttcccat
      181 aaaagtctta tcaaacttat atttcgatat aaactctata gttggagtac cgacaaaacc
      241 gtctaaactg agatttaata aacctccagt ggaaattata tttaaattat ttggttttga
      301 agtaactaca tttagtatat ccagcatatt tgtaacaagt gttacttttt tattactttc
      361 agctaacaac tttgcaagca agatgttaat tgtagagata tctaaaaata tagtttctct
      421 atcttcaatt aaattaaatg ctttttctgc tattattttc tttgttggaa tattaatttc
      481 ttttctgtct tttgtatcct gattttctag tgtttctcta gctagtacag ctcctccata
      541 aattcttctt attgaagaaa tcttttctat attttttaaa tcttttctta tacaatcttc
      601 tgtaacatta aatttagaac tgagctcttt gacagtaact ctaccttctt tttttaggat
      661 atttaatata gcttggattc tttcttctgc aaacattttc tacctctttt cgcaatatag
      721 tattatagta aatattataa gataaaatac aatatatcaa ctattttaac atgaaataca
      781 aaattaattt aatataaaaa gtatgttttt tctaactata tatttagaat ttagtaaata
      841 aaaaaattat aaaactaaga aggaaaagta aaacaataat aaaaaataaa aaacaataag
      901 caaaatgttg aaaataatac caaatcaata tataataaga ataaagaaag attaaagggg
      961 gatattttaa tgcaactaat cttagataca ggtaatgtgg aggagattaa ggagttatgt
     1021 acttgtttac caatagatgg tgtaactaca aatccaagta ttgtttcaaa agaaaaaaag
     1081 aattttaagc aacttataaa tgaaattggt gagattatag gtgaggatat gcctatacat
     1141 gctcaagtgt taagtacaaa gtatgaagaa atattagaag aagcattata tataagtagt
     1201 ttgagaaaaa atatatatgt aaaaatacct gtaacacaag atggtttaag agctataaaa
     1261 gaccttcaca gaaaaggtgt aaaaataact gctactgcaa tattcactgc tcatcaaggt
     1321 tttttagctg caaaggctgg agcaaattat attgcacctt atgtaaatag gcttgataat
     1381 atatctggtg atggagtagc tatggtttca gaacttataa aaataataga tacttataaa
     1441 atggatacaa aagtacttgc agccagtttt aaaaatgcac aacaagttat agaattaatg
     1501 caacatgggg tgcatagtgt tacagtacca tatgatattt gtaaatctat gatgaatcat
     1561 ccattaactg attggagtgt agataagttt atagaggatt gggagaatac ttttggaaaa
     1621 ggaagtaaaa caaataatat ttagtattat ggtaaaagag tagttttgtc caatttcaca
     1681 agaacttata taaaaagatg aaaatatgaa ttttcttttt aataatttcg ttattatctt
     1741 aagttaattc atattttcat cttttttaga tttctagtcc tataaatttc caccaaggga
     1801 atgttataca tattattata aagtaggtta aaggaatcaa agttaaaccg tatttgaaaa
     1861 taaccttgct attatacaga ttttcaccat gaccaaccat tattgtagca tgatgaaatg
     1921 gtaatatgta ctgtatgctt actataatgt agacaaatag acataaagta acactatttt
     1981 cctttagtat atgtaaactt ccaagtaatg gtattactac agatgatgta gtgacagcac
     2041 ttccaagaca tatattcaag attattgtga gagttatcaa aaacaatatt gaaataattt
     2101 ctgaagagtt tggtataaac tttatcaaat aatttcccat tatatctaca actccagagt
     2161 actttaacac tcctccaatt gaaaatgctg ctataaaaaa aataaggacc ttccaattta
     2221 tttcttttaa agtactaaat ccaactattt ttcttagtaa taaaagaagt acacaaattg
     2281 acattataat taatgtgttt atgttatgta tgaactgagt taaaaacata aaaaacatta
     2341 ttcctaggca taaaaatacg tgtttttgtt ctttgtttag caaattaaat tcttttttta
     2401 aattagaata tgaaaaatga agtttattac cctcaagatt ttcattagaa ataaatttta
     2461 ttgaatgcaa ttctttttta aagacaaagg taaataaaaa ataagttata aaacaagtaa
     2521 ttatagttgg aacagacata taaaaagccc attgacccca atttatatta caatttccaa
     2581 gttctagtac aacataattt agaagagtgt ctccatttac aaaaaacatt gatgtaaagg
     2641 tagatgctgt aaatatacta aataaaagta tagattttga atcttcagtt atctgttgtt
     2701 cttttaaaaa ctccttgtaa aaagcagata caagaataac ccttggaaat ggttgtggga
     2761 taaaaaatat taaaagtata cctaaaatat acgataaaag aatcattttt ttaggggtat
     2821 ttacagtatt taaaattaac ttctcagaaa taatttttgc gacacctgtt tttgtaactg
     2881 cattagtaat tatgtatgca agaattatta tgtaaaaatt ttctgtaaat aaaaactgta
     2941 aaataacctt tattggtgca atgttaaata taaacgctag aattacaaaa aacaatgcaa
     3001 caaaagtttt ttcaactgag tctacagccc atatcaagat agttaaaaaa gataagcata
     3061 tagaaaattt tatgttgaaa ctgtaattaa gagagaagta gagaattatg gtagctataa
     3121 cagtcatata aaattgtttt ggcttaagaa taatacccat ttttatattc acctccataa
     3181 tttattatat cataatggag gtgaatacaa tgaatgtgaa tacattttat aaaaagatta
     3241 ttcattgatt ctgtgattta caatagcttt agttttccaa tgtcctttct tatagtagat
     3301 aactgtaaca ataagaccta aagtccaacc aaaaggaata cccatccaaa ttccgtctgt
     3361 tccaaaaaat ttagaaagca tataagaagc tggaagtctt ccaagccata aagatactat
     3421 tgagcttata agtgcaaaca tggaatcacc agcacctttc attgcacttg aaagtacaaa
     3481 agaagttcca ataaataaga agaatggtcc tattataaat aagtaagaag agccaatttt
     3541 aatgacatct ttatcagtat tgaatagagc aattagattt tccctaaata gcaaaattaa
     3601 agcaataact gtaactgcta aaactaaggt catttttata gattctcgaa tgcctttttt
     3661 aactctttca ttttctccag cacctatgtt ttgagcaaca aaagtagaaa cagcagaacc
     3721 aagattcata ataggtaagc ttataaaatt ttctatccta agaccagcac caaaagctgc
     3781 catagcagat gtaccataac tattaactaa aaattgaaga gccatatttc caattgaaaa
     3841 caacatttgt tgaactccac ttggaagtcc taatctaagt ccatctttaa atattttgtt
     3901 atcatataca attcccttga ttttaaattt aagcacttca tgttttttat ttaaataaat
     3961 tatacttatt ataaatgata ctgcctgagc cattatagtg gcaagtgcaa cgccctcaac
     4021 acccattctt agcactacaa taaaagttaa gtctaaaact atatttagaa ttgtggctat
     4081 tatcagaaaa taaagtggag ttactgaatc tccaagtcct ctaagtattg cacttactga
     4141 attatatcca gcagaaaata atattccact aaatattata gtaagataca attttgattg
     4201 agcaaaaacg gattctggtg tattcataag cttaagcatt gggccaccaa atactattcc
     4261 aagaatactt attaatatag aaccaataaa taaaagtata tatgtagtat caatagtagc
     4321 ttttaccttt tttaaatctc ctgagccata aaattgtgac actaaaatag aaaatccaag
     4381 gctaacaccc ataagcgctg ccaccaataa aaacattata gggttagctc cagagactgc
     4441 cgccattgct tcttttccaa taaatctacc aactattata ctgtcagctg tattgtatag
     4501 ttgttgaaat aaactaccaa taagcatagg catggcaaaa aagaatatgg actttccctc
     4561 atgacctgta gttaaatctt tcaccttatt cctccaaata aaaaaattat taatttatta
     4621 tagtataatc ttaacataaa ctttatatcc aaactataaa taaattgtat caaaatatca
     4681 tatatttttt taaaatgtaa agaatataat tataatttga atttaataaa tcaatattta
     4741 atataatcga atattaatac aaaatcaata caatatatac gtatatattg acaaaattaa
     4801 ttatataaat taaaataata ttcgtaaaga aaaattcatg ttttgtactg tataacatat
     4861 aattttgaca atatgggtca taagtttcta ccggaatacc gtaaatattc tgactatgta
     4921 tactattatt tagttaatta aatatttaat taactgaatt atgaaggata cggctcagct
     4981 tatcaactac tgtgtcgttt ttttgtaaaa tttaatagga ggtgttgtta tgcaaacaac
     5041 aaacagtagt actatgcaga aactttttcc aattttgact aataaaaatg tcgacatgaa
     5101 gaaggaaata attgcaggag taactacttt tttaactatg gcttatataa tagctgtaaa
     5161 tccaaatatt ttatctgaga caggcatgcc tgcaggtgca cttgttacag gtacttgttt
     5221 agcagcagca tttggatgta ttttaatggg tgtagttgct aaccttcctt ttgctttagc
     5281 atcaggtatg ggtcttaatg cattttttgc atatacagta gttttacaaa tgggtgttcc
     5341 ttgggaagta gctcttacag cagtatttgt agaaggtatt atttttatag tattatcagt
     5401 aagtggagtt cgtgaggctg ttgtaaatgc gataccaaaa aatatgaaat tagctgttac
     5461 aggtggtata ggaatattta ttgcacttat aggtctagtt aacagtggaa ttgttattgg
     5521 agaccaagcc actcttatca aaatgggtag atttacacca gcagtaataa taacttgtgt
     5581 aggattaata attattgctg tattagataa aaaaagagtt aaaggttcta tactttttgg
     5641 aatagtagtg agttcattac ttgcttgggc atttgctttt ataaatccag agtatgcaca
     5701 aaaattaggt atatatttac ctggtggatt atttaaattc gaaagtttag caccaatagc
     5761 aggtaaaata gatttaggat atgtactaca tccaacaaat ataggtggtt ttttagtagt
     5821 agtttgtaca tttttatttg ttgatttttt tgatacagta ggtacattag ttggtgtttg
     5881 ttctaaagca aacatgttag atgaaaaagg gaatgttcct aatgtaggta gagccttact
     5941 tacagatgcg gttgcaacta cagttggtgc aggacttgga gtatctacag ttacaactta
     6001 tgttgagagt tcaacaggag ttatcgcagg tggaagaact ggatggacag caataacagt
     6061 tggaatttta ttcttagctg caatgttttt ctctcctgta tttatagcaa ttccatcatg
     6121 tgctacagca ccagctttaa tatatgttgg atatttaatg cttggtacag ttaaggatat
     6181 agagtttgat aatataactg aaggtgttcc agcttttgtt actattgctt gtatggcatt
     6241 aacatatagt ataggtgatg gtttaacttt aggtatatta acttatgttt tcgtaaatat
     6301 attttataat atatttggag ctaaaaaggc agaagacaaa aaacatgttt ctgtagtaat
     6361 gattgttctg gcaatattat ttataataaa actttggcta ctataatagg tattatttaa
     6421 aattttaatt taatataaaa taaagggctg taatttatta tcaattgtga tgataaacta
     6481 cagctctttt gtatttgttg tatttttgta tttattgtat tatttaataa tgtctattag
     6541 ttctccattt tgtaaagttt taggtgtaat tactatattg aactcttttt gcaaatcttt
     6601 tataatatct aattcttttt ttgttattat tgagattgtg ttaccacttc gatttcctct
     6661 agcagttcga ccacatctat gcaggtattc atttttactt tttggaaaat ccaagttaaa
     6721 aacatgactt acatccacaa tatctagtcc acgagcagat aaatcagttg taattaaaat
     6781 ctttgcttta ccaagtttaa atttatttat tgcattcttt ctatcttctt tttccatatt
     6841 tccaaaaatt cctattgctt tgtaattatg ataatttagt tttgatacta ggacttctat
     6901 atttttttca ttatttacaa atacaatagc tttttttgga tttgtagctg ctaatgcctt
     6961 tctaagaaaa gtaaatttat cccttatctc acctaataaa tatgagtgat tgatgttagg
     7021 atttatttgt gatttttcct ttgtttttat tatttcaaac tccttcataa gtttatcaca
     7081 aatttttata gtgctatcag taagacttgc agagcatcct ataatttgtc tatctcttaa
     7141 cgttgttctt attatgtctt ctatacaagt tatatttttt ccattcaata gattgtccac
     7201 ttcatctaag acaatagttt ttatattatg tgattttagt ttcttttgtt ttatcaagtc
     7261 taaaactctt ccacaagagc caattactat gtgtggtttt actgctttta tattttttat
     7321 ttgtttttgt atattgacct ccccaattaa agctaaagaa gtaacggaga gttctgcatt
     7381 tttagccaat aattcaacct ggtttgtaat ctgcattact aattcatgcg taggtgcaag
     7441 tataagagct tgtgtttctc tttttgatgt atcaattttt tcaaatatag gtaaaaggta
     7501 cgctagtgtt tttcctgttc cagtctgtga attaatcaat aaatccttat tttgaattat
     7561 atttcctata acaagtgact gaacttctgt tggagaagtt atgtcttgtt ttttgagtcc
     7621 atctattaga gtggaactta tttttagttg ttcaaatgta ttcatatttt gctccttata
     7681 ttttaataat tatagtcaac tattttttat tatacattgt ttattcaaat cgaactatat
     7741 attcttttat aattatgtgt aatttgaaag taaatatcaa ttatatttat acctttatat
     7801 ttctgatacc tttgcatttt atagatttct aaaataaaca aataaaagtt gtaattgttt
     7861 gatatttgtt atatattata tataacaaat atcaaaacta taatatggag ggaaattatg
     7921 ttaaaagtaa tcaatgtatc taaatcatat aaaaataaaa aagtagtaag tagtgtctca
     7981 tttgatgtaa atgatggaga gctttttggg tttataggac ataatggagc aggtaaaact
     8041 actactatta aagcaattgt tggaatacac gattttgaag agggagaggt actaataaat
     8101 tctaaatcta taaaaaaaca gcctgttgaa tgtaaaaagg aaatggcata tatacctgat
     8161 aatccagatt tatacgagtc attaactggt atacaatacc ttaattttat agctgacata
     8221 tttgaagttg ccaaagataa aagagaagag ttaataaaat attattcaaa taagtttgaa
     8281 ctcaataaag cattaggaga tttaatatct tcatattcgc atggtatgaa acaaaaatta
     8341 gctataattt cggctttgat acacagccca aaaatcttaa ttcttgatga accttttgta
     8401 ggtcttgacc caaaagcttc ctttatattg aaggaaatta tgagggagtt ttgtgacaaa
     8461 ggtggttgta tatttttctc aacacacgtt ttagaagttg ctgaaaaaat ttgtgataag
     8521 attgccataa taaaagatgg aaatataatt gcttatggaa ctacagaaga agttaaggga
     8581 agtaattcac ttgaaagtat tttcatggaa ttaatagaga aataaaatgt tttttataca
     8641 atatagtgtc taaagtgagg aatgataaaa tatgagcaat ctaagtatat taataaaaaa
     8701 taatataata aatgaattta aattaaatgc gttaaaaaaa gctgatggta gagaaaaaca
     8761 aaaaataatg ggaatgatgc tttcagttgt tataatagcg ggtctattaa ttttttatgt
     8821 aacgagctta agtctctctt tagttgatat cttaaagcaa ataaatcaac tggaaatgct
     8881 actgatattt ggttttggat tatcaacatt aacaactatt gttacatcat tatataaaac
     8941 gtcatcatat ctatttcaag caaaagattt agaccttttg actagtttac ctataaaaga
     9001 atctactgta ctagcaagta agatattaat gttggttgga gcaaactatt tattttcttc
     9061 aatatgtatg attatacctg cagtggttta ctttttaaat tctgatgtaa gtataactta
     9121 tttcccttat ttgatattgc tatttttagc tttaccatta ttaccgatag ttgcttcatc
     9181 aataattttt ctatttatag ggcagatatc atcaagaata aaatacaaaa atttagtatt
     9241 aatcataggt agcattatat tgatgttgct ttatacccta cttatgtcaa gacttaattc
     9301 tatgtcagtt gaaatgctaa agaatagtgt gtctatttca gagacaatta gaaaagtata
     9361 tcctcctata tattattttg ttgatgctct taaaacagga agtatagttt catttttagc
     9421 atttatagcc atctcaataa taccattttt tatgtttgta actctgtttg caaaaaaatt
     9481 taaagatata aatgctaaga tgagtgaagg atataagtca aaaaattatg aatttaaggg
     9541 tcaaaaaact tcaagacctt caaaagcttt attaaaaaaa gaatttaaga gatatacttc
     9601 ttcgtttata tactttttaa attcatctgc aggtttgtta tttctaatag taggtacaat
     9661 tttaatatta ttatttggag cagataaagt gggtgagtta ctgaaattga atatagattt
     9721 taatcttata aaaatacaat tattgggagt attcttcttt ataatagtaa tgaattgtac
     9781 aacatactgt tcaatttctc ttgaaggaaa aaacttatgg atactgaaat cttctccaat
     9841 agatgaaaga gaaatattct ggtcaaaaat attgatgaat tttttattga atgcaccact
     9901 atctatttta tgtctaatat tagtatctat aagattagac tttgaaattc agtttattat
     9961 tgtatcaatc tgtttgattg gaagtttttc aatgtttgta gcattgatgg gattattatc
    10021 aaatttatta tacccaaacc ttgattggaa aaatgaggtg gctgtagtaa aaagaagtgc
    10081 aagtatgata gttacaatgt tagtatcatt agcttatgta attatacttg gaggtatata
    10141 tgtattactt ggaatttcgt ttttaaatat atatattatt ttggcaagta tacttacttt
    10201 gatattagat tttatgatat ggagaattat ttctactaaa ggagtaaaaa tatttaaaaa
    10261 tttataagtg tatttatgtc aaataaagac ttatcttttt tagtcttgca aataataggt
    10321 taagtagtat actatgtata gtgatatgaa aaaatttagg agaaaataaa tgagaaaatt
    10381 atccaaaaga gaaaaagatt ttattcaata tggattttta ttatttttga tatgtattac
    10441 tacttattta gtattaacta ctttagatat aaaactaata cctaaaatta taaggctagt
    10501 aaataagact tatatatttc ttggcatatt gacaattata gtatatatga taattgaatc
    10561 tattgtaact catttgataa taaatgcagt tcaaaaaaca aaagtaaaat ttattggtat
    10621 taaaatggct acaatgggat tttactataa cttagttact ccatttgcat ctgggagtca
    10681 accaatgcaa atatatgcac ttacaaaata tgatgtaagc cttagtaaat cagtggctat
    10741 agttactaat aaaactgtag tatttcaaag tacagttact gtattttgtg gaattttaat
    10801 tttgctaaat aagtcattac tgatggagca agtacattct gtgaaagtct tgataacttt
    10861 tggaatgatt atgaatgtaa gtatgttgtt aggtggacta ctaatagtat ttagtccaaa
    10921 acaagtaaaa atgatagcag aagttttgat taatttttta tctaaattta aaacatttaa
    10981 atttttagat tcaaaacgtg atagaataaa tcattatatt gatgattata attattctat
    11041 aaaaatattt attaaaaatg taagaatctt agttttaagt atattactta ctgtgttaca
    11101 attaatcgca tatttcagta tagtttattg tgtgtataaa gcctcaaatt taagaggagt
    11161 ttcatatgta catataatga cattacaggt ctttttatat atggctatat caccaattcc
    11221 aacaccagga aatgttggag ctaatgaggt tacatttttt actatgttct ccaatataat
    11281 tccaaaagaa ttattggggt actctgtact cttatatagt gggtttgtat actattttat
    11341 attaatagtt tcaggtttat ttacatttgg aacgcattat acattaaatt cttggaaaaa
    11401 ggaagataaa gtaaattcta atttagataa ggttattgaa aaattaaatt aataaaataa
    11461 ttagggaaat tctatatata aatatggtgt tgaataagct atattatatt gagatatttc
    11521 ccttttttga ttaaaattat agaaatttga aataataagt aataaacaga aaaagtgata
    11581 ttgttttgaa aggagaaact atgaaacaag ataaacaaaa tgaaaaacaa agtgagattt
    11641 ctaagataaa acaaagcaat gataataaac ttgaaatagc tcaagaatta catgtaagta
    11701 aaaatatagg gaatatgctt ggatatagaa tagataagaa aaaaatgaat agaccaagtt
    11761 aatgaaaatg ttgaaaatgg tacattttaa aaaatatata taatgaaatg ttttattgtt
    11821 aaatttaaac ttattttaat ggaggaaaaa gtcgaaaaat atctaaaaag atatggatat
    11881 aaaaaatatt aatatatata tactataaac ttgacaaaat caacctttta ataactagca
    11941 aaaaatagca aaattatata agcgttattt aattgtcaaa aatgaaagct aaattgcatg
    12001 tcctaaaaaa aatgattgat aacatttatt tgtgtgctat aattatatag taaaacaata
    12061 agtatattgc ataatgtatg caaatcggga ggagagacgg acatggaagc atctatacac
    12121 acaattgcca gcaataattt attgataatt tttgctattg taagtataac tggaataatt
    12181 tgtagtaagc ttagtgaaat aataaaggtt ccagatgtag tgttatattt acttgtaggt
    12241 attttaatag gaccatcatt tttaaaattt atagatattc gtggatttca aatagaaaat
    12301 caactaatac ttacatttgg ttctgcattt attttatatt taggtggaaa agaaataagt
    12361 ttaaaagtat tgagaaatgt gaagatatct gtattcttat tagctacttt aggagttgtg
    12421 atatctgctt ttataatgca acaagtaata ggatttactt ttgggataag tgcaatgact
    12481 gctttactag caggaactat aatagcatca acagacccag ccactcttgt acctatattt
    12541 aatcaggtaa agataaagga tagggtaaaa caaactgtaa taagtgaatc agcttttaat
    12601 gatgcaacag gagctatact aacatcagca gtgttggctg taattttgtc aaataaattt
    12661 tcattaggtg aaaatattta tgaactgggg acaatggtta ttgtcggagt tttagttggt
    12721 ttaattacag gaatactgct tttgaaatta gttaatgata aaccttatgg aatatttaaa
    12781 gattttgcac caataatatc tgttatttca gttgtagttg catatgaatt atctacaaaa
    12841 ttaggtggaa gtggatatat gtcttgcttt attgtaggta taataactgg taacaagaaa
    12901 aactttaaaa tttggttaag tcaaaaatct tatgatgcag atttttatgt tgctgaaact
    12961 ttaggtacta tttgtcgtat ggcaatattt ataatattgg gtagccaagt taatttggct
    13021 cagttaagta aatattttat gccatctgta attacagtat tagtattaat gtttatagca
    13081 agaccacttt gcgttttagt ttgtacactt gtagacaggg aagcaaaatg gagtaaaagt
    13141 gaaatattat ttatgatgtg ggtaagggaa acaggcgtaa taccagcagc actttgtggt
    13201 attatttcag caatgaaagt tcctggatac gaagtgattt catctgtagt attcatgact
    13261 atactaatta cattagtaat acaaggaagt actacaaaat tagtagctaa aaaacttgga
    13321 ttattagaag aagaagtgat aaatataagt gaaaaagtat caacttttta aagttttgct
    13381 ttaaaatagt acctgttaat ggctatttta atattgtcta atgatgatta ttgaaatagt
    13441 cattttttta tgtataagta atttacagaa tttacatatt agacatattt attatcaaaa
    13501 tttgttgaag ctatgatata attagttgta tttaaaataa gaatagcaaa taagggagga
    13561 aatttatgtt tacggttatg gatattgtac agccagatac agtagaagaa gcgtactcaa
    13621 ttttaaataa aagaaaaact aaccaagtaa ttggtggaag tgctttttta agaatgggga
    13681 aaaaaagaat aggaacagga atagaattat ctaaattaaa tttagattat ataaaagagt
    13741 atgaagatta cgttgagatt ggttctatga ctacttttag aacattagaa acaagttcca
    13801 taataaaaaa taattttgga agaataatag aagattcagt taaaaatata ataggagttc
    13861 agtttagaaa tgtagtaaca gttggtgcaa cagtattttc taaatatggt ttttctgact
    13921 tgatagtagc attactttca ttagatacgg aagtagaatt atataatatt gggagaatta
    13981 gtcttgaaga gtttctaaat agagattatg agaaagattt acttattaag atatacataa
    14041 agaagacaaa taagaatgct tcttataaat cacttagaaa tgcaaagagt gattatccaa
    14101 ttctaaatgt atctgtatca aaacatatgg aacaatttaa gttatgtgta ggagcaagac
    14161 cgcagaaagc tacgattgca aaacaagcta gtgaatttct atctaacaat gaaatcaatg
    14221 aaattaatat agataaagca gtagaaatag catcagaaga actaactttt ggttctaaca
    14281 tgagagcatc tagggagtat agaaaagcta tgagtaaagt acttttaaaa agagctataa
    14341 tggaggttat ttaatgttag taaagattaa tataaatggg aagaaaaaaa gtgttgatat
    14401 agaaccagaa gaatatctgg ttgatacttt aagaaaagtt ggtaatttaa gtgtgaaaag
    14461 aggttgtgac acaggttgtt gtggtttatg tacagtttta attgacaaga aacctacatt
    14521 atcttgtgca acactgacat tgagagcttt agataaagaa ataactacaa ttgaaggttt
    14581 agaaaatgaa gttaaagaat ttagtgaagt tttggtaaaa gaaggagctg agcaatgtgg
    14641 tttctgttct cctggcttta tacttactgt acttgcaatg aaggatgagc ttgaaaatcc
    14701 tacagatgat gaaataaagc attatcttac aggaaatcta tgtagatgta cagggtatat
    14761 gggacagtta agagctatca aaacttatct ggaggtaaaa tagaacatga atatagttgg
    14821 aaaaggaatc aagaaaatag atggaatgag tatcacaaca ggaaagcctg tatatacaga
    14881 tgatttatca gcaaaagatg ctttggtggt aaagatactt agaagtcctc acgcttatgc
    14941 aaaaataaaa gatatagata catcaaaggc agaaatggtt gatggtgttg aatgtgtttt
    15001 aatatataaa gatgtaccaa aatctcgatt tacacttgct ggtcaaacat atccagagcc
    15061 atctccatat gatagattaa ttcttgaaga tgttgtaaga tatgtaggtg acgaagtagc
    15121 tatagtggca gctatagatg aaaaaactgc aattaaagca atgaatctta tcaaagtaaa
    15181 gtatgaagta cttacacctg ttttggattt tgaagaggca ataggaaata aaactatggt
    15241 acatgatgaa gatagacatt gtaactttga tataggtatg caaagagaaa aaaatatagt
    15301 atcccatcat gattatacaa aaggtgatgt agaaaaagta ttaagtaatt gtgatgtagt
    15361 gattgaagaa acttattata ctcaagctca agcacatgca atgatggaga cgtatagggc
    15421 atacaattat ttagaccata tgggaagatt ggttgtagta agttcaactc aaataccatt
    15481 tcatgtaaaa agacatttat ctcgtgcact agaaatacca gctagcaaaa ttagggttat
    15541 aaaacctaga attggtggcg gatttggtgg taaacaaact gcatgtgttg agattttttc
    15601 tgcaattgtt actttaaaaa cagggaaacc agctaaaata atttatgata gaaaagaaac
    15661 ttttaattgt tcaacaagta gacatgcaat gagattaaaa gttagactag gtgctacaaa
    15721 tgatggcata ataaaggcaa tagatataaa agcactttct gatacaggag catatggaga
    15781 gcatgcttct acaactattg gtttggttgg agaaaaaact ttaccaatgt ataataaagt
    15841 tgaagcaaca agatttattg cagatgtggt atatactaat aagatgccag caggagcact
    15901 tagagggtat ggagcatcac aaggatgttt tgctgttgaa tcaactataa atatgcttgc
    15961 taataaatta aaaatggacc caacagattt aaggttaaaa aatgtggtaa cagaaggtga
    16021 aactacattt gcatatggta aaactttaaa tagtgtcgat ttaataaaat gtataaataa
    16081 aggcaaagaa cttattggat ggaatgaaaa atatccttgt aaacatcttg ataatggaaa
    16141 aattagaagt gtgggtatgg caattactat gcaaggttct ggtatacaag gtcttgataa
    16201 gtcttcagct gaaataaaat tgaatgactg tggagattat actcttatga taggttctac
    16261 tgatatgggt acaggaagtg atacgatttt agctcaaatg gctgctgagg ttcttgatac
    16321 aagcattgaa aatataacag ttatatcagc tgatactgac ttagttccat atgacccagg
    16381 ttcatatgct tcaagtacta cttatgtaac aggtatggca gtagttaagg cagctcaaga
    16441 cttaagagaa aaaataattt ctgctggagc aactaaacta ggtgttgaga aggatgaagt
    16501 agaatttgat ggtataaaat taactagtaa aaaaggtagc actttattat tcgatatagc
    16561 agttgattct acaattggtc cagatactaa tcaattaata ggtcttgctt ctcatggtag
    16621 cccagtatct cctcctcctt ttatagcagg ttttgcagaa actgaaattg acacagaaac
    16681 tggaaaagtt gatttagtaa attatgtagc tgtagtagat tgtggaacgg ttataaataa
    16741 aaatctagct aagatacaag ttgaaggtgg aattgttcaa gggattggaa tggcattatt
    16801 tgaagaagtt agatacacag aaaaaggaag aatggacaca aatacattta tgcaatacaa
    16861 gattccagct agatgtgata ttggaaatgt taaagtagat tttgttgaaa cttatgaacc
    16921 aactggacca tttggtgcta aatctgttgg agaagttgtt ataaatacac ctttaccagc
    16981 aatacaagaa gctgtgttta atggaattgg tgtaagaata aatacactcc ctattacacc
    17041 tgaaaaagtt tttatggaaa tgaataaata attatttatg aaaatttaga ctagttttac
    17101 atgttaaaca accagttatg tcatacctgt tgaaagatat ttaataagta gttattataa
    17161 tattatgaat tttacttata aaatacaaaa ttaaataagg ggatgatgtt ttggctggta
    17221 atctaaataa tatgagagca gtaaataatt ttagaggaga taagaacatt ttagaatgtt
    17281 tagtcagctt tgagggtcgt tcaataagtc agagaaaagt aagggtattt tttaaagaaa
    17341 aacaaaatca aatagaaatt gattttgcag aagaggaaat ttctaaattg gttgaaaatg
    17401 ttgttttaaa tacatcatat caagaaatgt tatatgatga aatagagaaa caactggaaa
    17461 ttgattgtat aggtacttgg atgatattat ctaaattaaa agatggtagt agagttcact
    17521 gattttaaaa taaattatta gagcctaatt ttaaggctct tttttgctgt ttttaattaa
    17581 caatagaaaa tttatcttta gtttgtatat aattttaata tcatatattc tatatatata
    17641 aaattgaatt tgtatgtatt atattgtata atataaaatg aattgggaaa atagttcgct
    17701 aaaataattt gtttttataa aattactgtt taagtttata gattttgtat aaaataaagt
    17761 tatgttatta atttttttaa aaataaaact tttactagga gacagatatg agaaaaaata
    17821 gtattaatat agcactaact gcagcaatta cagcaatcta tgcagtttta acattatcat
    17881 tgggatttat aagttatgga ccaatacaat ttagggtagc agagattatg atgcttttgg
    17941 catttttaga taaaggatat atagtaggtc ttacattagg ttgtttttta gcaaatgtaa
    18001 taggaccata tggtgtacct gatataattt ttggaacatt agccacattt ataagtgcaa
    18061 gtatgattta tattactaga aagttaggta aacagaataa aagtacttta gttatagctt
    18121 ctttatggcc aactgttata aattcgattg tggttggtct aatgttaaat gtattctttg
    18181 ggcttccatt aattctatct atgatacagg taggttttgg agaatttgta gtagtaacaa
    18241 ttgtaggagt accatttttc tgttttttaa tgaaaaaata taaaaatgtc attaatatta
    18301 aattttaaat agtgtatagt aatttaatta attgagagta ttattagtga aaagaggtgt
    18361 ttatttgtcg aaggtaaaaa gattgactga tgtttggata tatattaatg ataagcaaaa
    18421 gtttacaata aaagagttgt cagaggaatt taatctttca gctaaaacaa tacaacgata
    18481 tttaaaagaa ttaaataaaa tgggacttcc aattcaagca gaacaaggta gaaatggagg
    18541 ttatagggtg ctaaataata gctatatacc tcctgttata tttacagaaa aagaagttat
    18601 gattatacta tttgcactta agtcacttca gatttataat tataagttaa tggaaataga
    18661 aattaattct ataatgagaa aagtaagtta tgaacgtaaa agcagtataa aagtaggtat
    18721 agaaaatatt aaaagataca ttggctttgt agctaatgat actaatgatg gagattttaa
    18781 gagtagtaat gtaactgagt tttttagagc ttcttcagaa tctctaattt taaatattaa
    18841 gtataagtgt ggtaatcaga ttttggaaaa aaacgtatgc cctataggta tatatttaaa
    18901 taagggagca tggttttcac cagcatatga ttgtaaaagt ggtaaaataa tattagttca
    18961 tatagataat ataattgata taaaaagaac aggagaaagt aaaaaaatac atataaactt
    19021 ggaagaatgg ttacatgaag tatataacaa tttatatgga aatagttcaa ctactaaaaa
    19081 atttggtgaa attatttatc taaatgtatt attaactaaa gaaggtgttt ctaaaataaa
    19141 ggacagttct tggaatttag atatggagct aaatgaagat ggtagtggaa taattagtac
    19201 attcataaag gttgaagata tagattgtta tgcttcgatt ttatttttta ttggaaataa
    19261 tgctaaggtt atagagccaa aatttttgaa taagctactt tatgataagg ccaatgagtt
    19321 aagatatttt tatgaagaaa atatggtata atatttagaa atgttgaaat taaataatta
    19381 ttaaggagat atacgttata atggaaaatt ttaataagaa tgctaaaata attggtattg
    19441 gagctgaagg tattaatata ataaatgaag tagaagaaaa aataaaagca aatatggata
    19501 tagaaaaaat aaacataaat caagagattg aaaaagaata tgttagaagt cttttagatg
    19561 gtgtagatat attatttttg atatattcat ctgaagataa acatattaga gatattataa
    19621 aagctgtttc atatatgtca aacgaaagaa gagttctatc tataggaatg gattgttcag
    19681 agaaagaaaa taaagaagat ttagagcttg ggagagagtt taaaatcaat aatgatagta
    19741 tatttaaatt tgttgattta atgaatatca tggtagagtc tatttctgat tcttgcatga
    19801 taaatataga tattactgat ttaaaagaag ctattgtagg agataaagga attaagtatt
    19861 cttttgaaga gtttgaagat acaaagtcat atagcgagat agctgacatt ttatttgaca
    19921 ggatggaata tattggtgag gaatttataa gtaagaaagg aattgtattt gttgaaggaa
    19981 gtccagaatt ttctataatg gaattgaatg atttaataag taatattcag agcaaggtag
    20041 aagaaagcta tgaagtaata ttttctttat atataaagga aaatttaaat ggaaatatta
    20101 gagtaggctt attgtataat tagtatattt tagatattaa ggagagtgta tatgtctgaa
    20161 aatataagag gtacagagta ttggttaatg gaagaatttt tttatcagga aacagacaca
    20221 ccacagattt ttagagaaga aagcataatt gcacttggat ttgatataaa aataaattta
    20281 aaaaaagtat tcagtatggg gaaaaaatca gaaaagtata ttaatgagaa ttgtaatgat
    20341 aaagatttta taaaaaagtt tatgtcgatt aaaaaaggag attatttttt atataaagca
    20401 tatcaaaata tagaagaaaa agttaaatgt aatgtgtcta ttggcatagt tgaagaagat
    20461 tttgaaaatg gatatgaatt aagtcatatt ttagggcata cactaccagt aaaatggatg
    20521 cataattttg atacagtttc aaattgtaaa gtatatacaa gtgaatttta taaattaaat
    20581 aataatgata ttagctcata tttagaaatt attaagtcac aagataagaa attattgaga
    20641 aaaagaatag aagaaagtga aaataataaa tggtatttaa aaaactatta ttataaaaat
    20701 gtagataagt gtgtagatga tgaagaatta tttattcagc ccattaatct agaacaatta
    20761 gaaagcctaa aaaatataaa gacagatgat tatattttat tgtataatag cgagaaagta
    20821 atttgtgaaa atgaccatac aatgaagagt ctatttggcg tatgtcaagt tatggaaggg
    20881 ttcgataaag agaaagtaag tgctttggag ggtggatatt tttttcctgt tagatggata
    20941 gagtatgaaa aggagaatat agacggaaat gcatgggtta tatttgaaaa taatagtata
    21001 gttgaaaagt atgtaaaaag atttactaat aaaatgccat taaatactat actttatgga
    21061 ccaccaggaa ctggtaaaac atacaataca aaacagatgg tttacaatct agtaagtgaa
    21121 accagtctaa gaaacagata ctatacaggt tacttagatt ataaaaacaa tgtagaattt
    21181 tgtacatttc atcaatcata tggatatgag gaatttatag agggtcttaa gtctgatggt
    21241 gaaggcaatt ttaagccaga agatgggata ttaaaggata tatctataga agcatgttat
    21301 aatgcattga aatttgaaaa aaagatgagc tttgagttgg aaaaagatag cttgacttta
    21361 gaaattataa aagacaggaa aaagaaatta gtattagaaa atatagaata tagtgagagt
    21421 tttaattttg aagaatcaga aaactatgtt ttaataatag atgaaattaa tagagggaat
    21481 gtatctaaaa tatttggtga gctaataaca ttattggaag atgataaaag acttactaaa
    21541 tcaaatcaaa ctattgtcaa actaccatat tcaaaggaaa aattttctct acctccaaat
    21601 ttgtatatag ttggaactat gaacacatca gataaatcaa tagcactttt agatatagct
    21661 ttaagaagaa ggtttaattt tgaagaaatt atgccagatt atgatttatt gtctattgta
    21721 gatggtatag atattagaaa aatgctatat acaatcaata aaaggataga gtttttatat
    21781 gatagagacc atgttattgg acaagcttat ctacttgctg tagaaaatat taatgatata
    21841 gtagtagtat ttagaagtaa aataatacca cttcttcaag agtattttta ttatgattca
    21901 gaaaaagtag gtttgatttt aggaggaatt ggaagaaatg aaaaagataa atacattgtt
    21961 tataaagaaa aacttatagc ttctgagtta tttaaaaata ataatgcctc aataatggag
    22021 agtaaagtta actattgtat aaaacaaaac atatctagtg aggagctaaa aaatatatat
    22081 gagtaaaaat atatatgtta aggaaaccta tgaatggata aggataggta atggtgaaaa
    22141 tgagcttaca gaaattgaat atgaaaaatt gcttaagtat ctagagaaca ataatgatgt
    22201 attaaaaagt aatataatag atattaaata caaaaaactt agatttataa actatgtagg
    22261 catcatatgt tttgaaaatg taatacttga aatacttcct aaattgtcat taagtgataa
    22321 tcttgtaaaa gatagagaga tactattaca gatgctttct atatgtaata aaatcccaat
    22381 tacaatgaat gaaaaaataa gattgagttt gaaaaattat aatctcttaa atttttttgt
    22441 tatgtatttc attgagagta tgcaaacaca gatgaaaaaa ggtatttatt ttgaatatat
    22501 aaataaaata gagaacttaa atgttatgag gggtaaaata ttattaagta catatgcaaa
    22561 agaaaaaggc atttctccaa tgaaaataag atgtgaatat gatgagtata gtgaaaataa
    22621 tttcttgaat caagttctta aaaaagcatg tatatctatt ttatgtagaa taaatgacaa
    22681 ttcaattcaa ggcaagatta aaaaaatttt aagctatttt caaaatgtag atttaattca
    22741 tatagataga aaaaaactgt tggattataa attttataaa aacaatgata gatttaaaga
    22801 ttgttattta ctagctagac ttctactttt aaacttgtct atggataata gtcaaaataa
    22861 tcaagaggca ttttctatat tatttgaaat aaatactttg tatgaagaat atataggaat
    22921 tttaatcaaa agtatatggg acaattcatt tagagaaaca tatatacaag ataagagtaa
    22981 atttcttttg aaaaatgaac aaacaggtaa gaaaaacttt aatttaagac cggatatagt
    23041 tttatatgac ttaaaaaatg aatatgaaat tataattgac actaaatgga aagctattga
    23101 agtagattca aatgtttttt ataggtcaag tgatatatac cagatgtatg catatataac
    23161 agcatatgaa aatgcaaaaa gatgtatatt attatatcct tgtattcaaa aagataagaa
    23221 ttatagttcc tggaaattat cagaatcatt taagggtaag tttatagaag caaaaactgt
    23281 gaggttagat gatataaaaa acacaaaaaa tgatttaaaa aagataattt ttaattataa
    23341 attttaaaaa taagaatttt aaaatttata aaagtaattt tatataggta taaaaattac
    23401 ga
//
LOCUS       DAGQVA010000060        23314 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.060, whole genome shotgun sequence.
ACCESSION   DAGQVA010000060 DAGQVA010000000
VERSION     DAGQVA010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23314
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.060"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..867
                     /locus_tag="MIV85_002656"
     CDS             <1..867
                     /locus_tag="MIV85_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:607..609,aa:Sec)
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBY2961985.1"
                     /translation="VPIMTKLGLKLVRGEEIGPPEEEGYIMRGIRKNFFHELRGSERA
                     IDMLVKKMKGESFETEYPMPEFDRVTPMKPVKDLSKIKLALVTSGGIVPIDNPDKIES
                     SSATKYGIYDLTDMDSMSNKEFTTIHGGYDRAYVLENPNLVVPLDVVRELEKEGVIGE
                     LVDYFITTTGTGTSVGNSKRFGEEFSKKLLEDDVDAVILTSTUGTCTRCGATMVKEIE
                     RAGIAVVHICTVVPISLTIGANRIVPAVGIPYPLGNPMLGEEESKKIRKNIVLKALNA
                     LTEDIEEQTVFE"
     gene            1145..1876
                     /locus_tag="MIV85_002657"
     CDS             1145..1876
                     /locus_tag="MIV85_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2961986.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            1878..3236
                     /locus_tag="MIV85_002658"
     CDS             1878..3236
                     /locus_tag="MIV85_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBY2961987.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            3275..3760
                     /locus_tag="MIV85_002659"
     CDS             3275..3760
                     /locus_tag="MIV85_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961988.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(4023..4259)
                     /locus_tag="MIV85_002660"
     CDS             complement(4023..4259)
                     /locus_tag="MIV85_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2961989.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTDKIQTAS"
     gene            complement(4414..4638)
                     /locus_tag="MIV85_002661"
     CDS             complement(4414..4638)
                     /locus_tag="MIV85_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBY2961990.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(4735..5988)
                     /locus_tag="MIV85_002662"
     CDS             complement(4735..5988)
                     /locus_tag="MIV85_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBY2961991.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            6248..7237
                     /locus_tag="MIV85_002663"
     CDS             6248..7237
                     /locus_tag="MIV85_002663"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBY2961992.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            7309..8049
                     /locus_tag="MIV85_002664"
     CDS             7309..8049
                     /locus_tag="MIV85_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBY2961993.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            8265..9416
                     /locus_tag="MIV85_002665"
     CDS             8265..9416
                     /locus_tag="MIV85_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBY2961994.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            9441..10196
                     /locus_tag="MIV85_002666"
     CDS             9441..10196
                     /locus_tag="MIV85_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBY2961995.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            10388..12775
                     /locus_tag="MIV85_002667"
     CDS             10388..12775
                     /locus_tag="MIV85_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBY2961996.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGCTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(13006..13239)
                     /locus_tag="MIV85_002668"
     CDS             complement(13006..13239)
                     /locus_tag="MIV85_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBY2961997.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            13528..14118
                     /locus_tag="MIV85_002669"
     CDS             13528..14118
                     /locus_tag="MIV85_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2961998.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEYFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            14232..15077
                     /locus_tag="MIV85_002670"
     CDS             14232..15077
                     /locus_tag="MIV85_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2961999.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENESNKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            15074..15757
                     /locus_tag="MIV85_002671"
     CDS             15074..15757
                     /locus_tag="MIV85_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962000.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            15754..16470
                     /locus_tag="MIV85_002672"
     CDS             15754..16470
                     /locus_tag="MIV85_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962001.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            16567..16830
                     /locus_tag="MIV85_002673"
     CDS             16567..16830
                     /locus_tag="MIV85_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962002.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            16802..17257
                     /gene="def"
                     /locus_tag="MIV85_002674"
     CDS             16802..17257
                     /gene="def"
                     /locus_tag="MIV85_002674"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBY2962003.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIEQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            17309..17770
                     /locus_tag="MIV85_002675"
     CDS             17309..17770
                     /locus_tag="MIV85_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBY2962004.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            17820..18722
                     /locus_tag="MIV85_002676"
     CDS             17820..18722
                     /locus_tag="MIV85_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962005.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            19092..19904
                     /locus_tag="MIV85_002677"
     CDS             19092..19904
                     /locus_tag="MIV85_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBY2962006.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            20952..21713
                     /locus_tag="MIV85_002678"
     CDS             20952..21713
                     /locus_tag="MIV85_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBY2962007.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            21778..22560
                     /locus_tag="MIV85_002679"
     CDS             21778..22560
                     /locus_tag="MIV85_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBY2962008.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            22827..23246
                     /locus_tag="MIV85_002680"
     CDS             22827..23246
                     /locus_tag="MIV85_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBY2962009.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
BASE COUNT         9304 a         2392 c         3806 g         7812 t
ORIGIN      
        1 gttccaataa tgacaaaact aggtcttaaa ttggttagag gtgaggaaat aggacctcct
       61 gaagaggaag gatatataat gagaggaata agaaaaaatt tcttccatga acttagaggg
      121 tctgaaagag caattgatat gttggttaaa aagatgaaag gggaaagctt tgaaactgag
      181 tatccaatgc ctgaatttga tagagttaca cctatgaaac ctgttaaaga tttatctaag
      241 ataaaacttg ccctagtaac ttctggaggg atagttccaa ttgataatcc agacaaaatt
      301 gaatcttcaa gtgctactaa atatggaatt tacgatttaa cagatatgga ttctatgtca
      361 aataaagaat ttacaactat acatgggggg tatgacagag catatgtcct tgaaaatcca
      421 aatttagttg taccactaga tgtagttaga gagcttgaaa aagaaggtgt aattggagaa
      481 ttagtagatt attttataac tactacagga acaggaacga gtgttggcaa ttctaagaga
      541 tttggagaag agttttctaa aaaattgtta gaagatgatg tagatgctgt aattttaact
      601 tctacatgag gtacttgtac tcgttgtgga gcaacgatgg taaaagagat tgagagagct
      661 ggtatagcag ttgttcatat atgtacagta gtaccaatat cacttacaat aggagctaat
      721 agaattgttc cagcagtagg gataccatat ccacttggaa atcctatgtt aggagaagag
      781 gaaagtaaaa aaattagaaa gaatatagtt ttaaaagctt taaatgcact aacagaagat
      841 atagaagaac aaacagtatt tgaataataa aaatacaaca caacactgaa ataaaaaaag
      901 atatcaaaaa ataatttttt aaaattattt tacgatatct tttttttatt aggtaaattc
      961 gaaatttgca ttttttaaaa ttaaatttat aaaagtgata aattagttta ttataatatt
     1021 gatacacaaa ttcaaattag atatactatg aaaagcgaga ttattacatt ttggaacaaa
     1081 tattcaacat attagatcat attaattgaa cagaaaaaat taactttata taataattag
     1141 aataatgata agaaagaagg tgtatatatt gatttcaatt gccatttgtg atgatgaatc
     1201 ctatatgcta aatcatttaa aggaaaatat agaattatac atgaagcaga agaatttatt
     1261 atataatata gagcttttta ataaagtaga agatttacta tgcaatcatg aaaagtttaa
     1321 tattgtattt ttagatatac agatggaaga gattaacgga atgcaggcag ctagaaaatt
     1381 aaggtcatat ggtaatgagt gctttataat tttcgttaca gttttaaatg aatttgtatt
     1441 tgatgctttt gaagtagatg ctataaatta tctgataaaa cctctatcta atgagaaact
     1501 atataaaact ttggataaaa tagttacaaa acttgatgat aatgaaagta attatatcac
     1561 aatacaaaaa ggttattcat attggaaatt aaaacttgct gatattttat attgtgaagt
     1621 tataaaaaga aagatttatg ttcatttaaa gaaagagact gtagattatt atgagactat
     1681 tgaaaattta gagagaagtt taccaacaaa tttttttagg tgtcatcgta gttatataat
     1741 caatttacaa tatgtatatg gatatgaaaa tggtaatgca gttatggaaa gtggagatag
     1801 aatacctgtt tctagactac gtcaacaaat attttcaaaa gttatgcttg agttcatgaa
     1861 aaataggagg atataagatg attaatttat tttcttccga tttattttta aagtacagtt
     1921 ttttattttc ttttattgta tatagaattt taatggtaat agtgcaatac tattttctaa
     1981 tcagttttac aaatgttaat tcaaaatttt ggtgttttat tttatattcg ataatttcaa
     2041 tttttttaat cattataaat acatatttta atttatataa tttattttct tcacagattc
     2101 tattttttct tatgactttt ttatttgtaa agtacataat aaaacaatct actgttttat
     2161 ctatagtatc aactttgtta gtatatttaa ttgaacaatt agtatatgga tttacagctc
     2221 cattaaatta cttgatattt actagtgata taaatacaga tatttataaa tttgatataa
     2281 atatgggact atcttcttta attactatta taatagctgg atttatatat tggtatagtt
     2341 ctaaaaagtt taatattaag gtcatgaact ttgataaata tatagcaatt ttgatgattc
     2401 cattgttgct tataatatta tttatgcaat catttgaata tagttcaaat ataaatatag
     2461 atacaagtct tgggattgta aagctgctat taaatacttc tataactgaa gaaattcaag
     2521 cttttctttt ttctataatt ggaactatat gtgtattttt ttctctattt acctttaaga
     2581 aactaattca agctctcgaa gatgacaagg agagggcaat tatgaatcaa cagattcatg
     2641 ctcaaaaaaa ctatattgaa gaagcgaaat cacgattatc acaaactata tcctttagac
     2701 atgattttaa taatcattta gctattgtca atggattgtt gaaaaaagac caaattttaa
     2761 aagcacaaga ttatttaaat aagcttgaaa aagtaacaag tgacctatca ttttcttgta
     2821 atacacagaa tattgttatt gatgctcttt tcaacaataa attaagtata gcaaaacaat
     2881 taggcataga ggtagattgt gaagtaatta taccccaaag cactaacatg aacgattttg
     2941 acctatgtat agtgtttgct aatgctattg acaatgcaat taaagcttgt agagttgtag
     3001 ataaacaaaa taggtattta aagctttcca ctaagttaga gggtggattt tttatgatag
     3061 aaataaaaaa tagctataat ccaataaata attatacaag tggctcaggt ataggtcttt
     3121 taaatataaa agaaattgct aaaaaatatc aaggggctat aagtatagat aagacatcag
     3181 attattttca aataaatgta ttgctggtta tttcattaca ttgcgctagt atttgataac
     3241 aatttcattg aaaatagtat ttgtaagcta tattatgtac ttgaatagag aaagtttgat
     3301 atatagaaat gaggaggtta ctaaaatgaa agttggaaat ataaatggtc aagcaccaat
     3361 tacaaatggt ttagatagtt gtcaaagtga ggtacaaggc ttagaacaaa agaaaaaatc
     3421 attacaggat gaaatagaga aagtaagaag tgataaaagt attgatggtg aaacagccaa
     3481 attaaaaata gaagctttaa aaaaagaaat ggaagagatt gaaaataaaa ttcaagagtt
     3541 aaaaggaaat aaagcaaaaa aaacaaataa agaagaaaat aatgtttcag aagtaaataa
     3601 taatctatta gagagaaaaa aagaaccttc taataatgaa aatgtaaaac aattatatga
     3661 tgtttttgaa agaagcaatg tagacgaaca atgggataat acttatcgtg ttctccaaga
     3721 tgataaaaac ttaaaagtaa aatttaatag acctatatag tttatttata aaaatagtta
     3781 atattttaat tatcaccact ttttagaaga atacacactt tattttaaag acccacatat
     3841 ttatttacag ttagcacatt tatatgtggt tttataacta ttatttacaa gtctatattg
     3901 ataactttta catagtatat aatgtttaaa tacttattca aatttatcta tacataaaca
     3961 aaaaaagaga ttttaaaatc tctttttaga ttgttgactt atggcttttt gatttaataa
     4021 aatcaagaag ccgtttgaat tttatctgtt ggctgatacc cttctgatat tgaaacacca
     4081 tttttgtttc caaaatcgtt taaaattaag aacttattat gaatgactat ttcattatga
     4141 acaataagca gataacatga atcttcaatc aatgttttaa cagtagcatt aaatgcttgc
     4201 ttatacagtt ctatcgtttg tttgaactgt ccattaaagt aaatatgagt caataacata
     4261 actatatcta cacaaattaa tataaatttt ttatactgta cattatctaa ctgttgatta
     4321 tctgtattac aacatgattg aatttaaaaa gccatcaaca catagaatgt tgatggcctg
     4381 aaaatagatt taaaatctct tttttattat atattaatta ttttttaaat ttatattttt
     4441 tgcatcagat tttctaatag ctaagtcaaa ccctctaaat ctaatcacta tagggtcatt
     4501 aagaggagct atctttttca cttcaacttc agtgccatct attagtccta aggctagaag
     4561 tctcttcata agtttttcat ttccagctat attgtctata attccctttt gtccaagttt
     4621 taagttgtaa acagtcatta ttaacacctc ctaatgaaaa tcattatcaa actttatatt
     4681 tataatatat aacaaaaaga gcaaattgtc aatatataac aaaaaataaa catactaagt
     4741 tagtatgttt ataaaaaata gtatacatgg gatactaata gcatctagca aaaaaccact
     4801 tactaatggt acaactaaaa aggcttttgg agaatcacca tatttttgtg tcaaagaact
     4861 catatttgcc agagcgttcg gagtagctcc tattccatgt ccaatcaaac cacttattat
     4921 gatggcagaa tcaaaatctt ttccaagtac tctaaagcaa ataaatattg aaaataggat
     4981 tataaagatt acttgaaaag ttactattaa gagaatagga ggtaataatg tagataattc
     5041 aaataaatct atattcataa gtgataaagt taaaaaaatt cccaatgaaa gttcttttaa
     5101 aaaatctata agtttaaaat ttaattctag tatatttatc ttatcattta aatttctaaa
     5161 aataacagcc gaaaacatac aagttacaac agagggtaat agtatattaa acgttatata
     5221 gaagcatcta cttataattt ctcctgtatt tatacaaata aatatgagaa gaacctgttc
     5281 caaaaataca gatggtgtta ttgtttcgga gaagttatta ttttttatcc tattcttatt
     5341 tctaaaaaat ttacttccaa atctctttag atttctatta tatctaggaa tcgacaagtc
     5401 tatatttgat gatggtttta atttatattt atttattaga aatttagcta caggacatcc
     5461 caatatacca cccataataa gtcctattgt tgcagcagat aatccaaccc caactgctcc
     5521 ttctataccg agattttcta ttgtaagtcc aaatgcagca gaataaccat gaccaccttc
     5581 catagataca tttccacaca taagccctaa aagaggttca agttttataa tctttgatat
     5641 tgtaatagct aatatatttt gacaaaatgc caatactcca cacaaaatcc aatatctaaa
     5701 taatacacta ccacctttct ttataagatt tatgcttatt tcaagtccta tagttgtaaa
     5761 aaagaaggtt atgaaatttg gcattaaatt tccacttata gatatatctg ctatattaaa
     5821 atatttaaaa aataaattta gaaaacaaaa taatagacct cctattactg gtgcaggtat
     5881 acagaaatta tttaaaaagt taactttatt cttcaataaa ttaccaatta aaaagaagaa
     5941 tatagatagt gtcaaggttt gcactatatc aaaacttaag gtaatcaaaa taagtcctcc
     6001 tttgtaattc aaagttttaa ttatataact taaattctta tgtattgaaa ttttattatc
     6061 aaatgtatat taataaatgt atattaaaaa gaatcagtag atataattag atagtcataa
     6121 attaaattaa aatattttaa tgagatatga cttttttaga attaaaaacc gtagtatatt
     6181 gatataatag aaataagact taaaaatctg ttgatagtat tatttataag tacagtagga
     6241 ggataaaatg tttgaaaatt tacctaagat agatttacat tgccacttag atggaagtgt
     6301 tagagtagaa accatgcttg atatagctat taaagagaaa atagatttac cttcaaataa
     6361 tatggatgaa ataaaaaaat tagcaaaggt ttcttttaat tgtacttcac tagatgaata
     6421 tttagaaaaa tttgatttac ccttaaaagt aatgcaatct aaggaaaatt taaaaagaat
     6481 tacttttgaa cttttggaag atgcaagtag agaaaatgta aaatatattg aaattagatt
     6541 tgcaccatta cttcacaccc aaaaaggtat gagtgttaaa aatataattg agggtataat
     6601 tgaaggaatt agagaagctg aaagtattta tgatataaaa ggcaatttaa tattaggttg
     6661 tatgagaaca atgacctcaa aagaggcatt attagtaatt gaagaaggga aatcatttgt
     6721 aaataaaggt gttgtagcag tagacttgtg tggtccagag aaagagggat tttgtaagga
     6781 atataaagat gtttttaaat tagcaagaga atatggatat aaagttacaa tacatgcagg
     6841 agaagctgca agtggagaaa atgtattgga tgctataaat attttaaagg cggataggat
     6901 tggtcatggg gtaaaaatta aagaccataa aaaggcgtat aatttagtta aagataaaaa
     6961 aatattgctt gaattatgtc caactagtaa tgtacaaact aagacagtag attcttatga
     7021 agcacatcca ttttatactt tttataaaga taatttacat gtaagtataa atactgataa
     7081 tagaactgta tcagatataa atttaagttc agaactaaat gttatatttg atacttttaa
     7141 actaggatta gaagactata aaataattta tagaaatgca gtagaagcta gttttgcaga
     7201 taaagaaact aaagagtatt tgaatagttt aatttaatag ataaaaatat ttaaacttta
     7261 aattaagcta ttaaattgat aaaaatacat tgtattagga gaaaaaatgt gaaagattat
     7321 gaagatgttg tttatattaa actagtcaaa aaagaacttg aagaatggaa gaaaaatata
     7381 ttaaagaaac cttctatatt tgacaaagca tcaaagggta tacagaataa atttaatgga
     7441 gtattgccag ataaatatca tgaaataatt acttcttcta taaaagtaat gacaaaaacc
     7501 gtactgtttg gatataaata tgctacaaag ccaccactta gaaatatgtc attagaagaa
     7561 agagaaaaat tagttttaga aaaagctaaa acttacaaga ctacagcaat gattgaaggg
     7621 gcaggaacag gggcaggagg aatcctctta ggtttatctg attttccttt gcttttaggt
     7681 attaaagtga aatttttata tgatgtagct tcaatatatg gatatgatgt taaagattat
     7741 agagaaagga tttatatatt aaatatatta cagttggctt tttctagtca acagcatata
     7801 aacaaaactt ttaaattgat gaataactgg gatgaatatg taaatagtct accagaagac
     7861 atcaatgatt ttgattggag aacatttcaa caagagtata gggattattt agatttagct
     7921 aagtttttac aactaatgcc tggaatagga gcatttgtag gattttatgt gaatggaaaa
     7981 ttaattgata aattatgtga aactgctgtg tctgcttata gattgaggat tcgagagctt
     8041 aagttataag aaaaattata acataaaaaa ttagttatac aatatatcta tatgtatcta
     8101 attttgcatt gataaaaaca attatggata aaaggtaaag catgatagaa tctaatgtag
     8161 aggtttgtat tttaatggaa aaatttagtt tttattgctt aagatacaaa ttgaattacg
     8221 aagagattga attatgaaga gaagtaattg ggaggaatat tttcatgaca aatttgccaa
     8281 aacaatttga tagcttcaat gaagctagac aaaaaggatt tataaatgca aaggaactta
     8341 aggaaagtgg gaaaaagatg gttggagttt tctgtacatt tactccagtt gaaattccaa
     8401 tggcagctgg agcaactgta gtaggtgtat gcggcgttag tgaagagcca atacctgatg
     8461 cagaaagggt gcttccaaga aatctttgtc ctttaattaa atcaagctat ggacatgcaa
     8521 taacagatac ctgtccttat ttctattttt ctgatttgtt gataggagaa accacttgtg
     8581 atggtaagaa aaaaatgtat gaagaacttg caaaagttaa gccaacatat gtaatgcatt
     8641 tgccaaatac ttcaaaagga gaatttgcct ataaactttg gaaagatgaa atgataagat
     8701 taaaagaaga ggttgagaaa tctttaggtg taactataac tgaagaagat ataagaactg
     8761 ctataaaaga taaaaatgaa gaaagagaac ttttaaaaga gttttatgca cttggtaaat
     8821 tacaaccatc tgcacttaca ggccttgagt tacataatgt tttatatcaa gcaggtttta
     8881 aatttgaccg tgcagaactt aaacattctt taagaaaagt tatagatgat atgaaagaaa
     8941 gatatgaaaa aggtgaatgt cctgttcaaa aagataagcc aagaatattg ataacaggtt
     9001 ctcctattgg tggaataagc gaaaaaatag ttaaaacttt agaagatgca ggggcatcag
     9061 tcgttgcata tgaactttgt ggagctatta gatcaaacga tttattggtt gatgaagaaa
     9121 tagaagatgt atatgatgct ttaacacaaa aatatataaa tataggttgt tcttgtatga
     9181 tgaataatga caatcgtatt gaattattag atagaataat agatgaatat aatgtagatg
     9241 ctgtaataga tgtagtttta caagcatgtc atacatttaa tatagaaagt tatagaataa
     9301 gagaatttgt tacaaaagaa aaaaataagc catttatgtc tcttgaaact gattattcaa
     9361 aatcagatac tgaacaatta agaactagat ttgaagcgtt tgtagagatg ttgtaggaat
     9421 aaataaaagt aggaggaact atgtttagta taggagttga ctcagggtca gtggcaacaa
     9481 agggtgtgct atttgatggt gaaaaaatta ttaagaaaat aattatacca actggatgga
     9541 gccctaaaag tacatctaaa caggtctatg agttgctaag tagtgaaatt gacaaaaaag
     9601 atataaaaaa ggtggtaggt acaggttatg gaaggggagt aatggatttt gctgataaga
     9661 aagtaacaga aataacttgt catactagag gtatttactt tttaaacaag aacataagga
     9721 ctattttaga tgtaggtggt caagatagta aagttataaa tttagataga gatggaaatg
     9781 tatttaactt tataatgaat gataagtgtg ctgcaggaac tggtcgattt ttagagatta
     9841 cttctaacct tttaggaagc gatattgaaa gtatagatac attagctaaa ggatatgaac
     9901 cagttaatat atctagtatg tgtacagttt ttgctgagtc tgaaattgta agtcttctag
     9961 ctcaaaacat ttctactgga gaggtagcag cagggatact taaatctatt gcaaataaat
    10021 ccacctcaat gttagcaaga ggtgaggtaa tagatgaagt tgcatttact ggagggcttg
    10081 caaaaagtaa agaactagta aaaatgatag aagaaatact gggtaaaaaa atttttattg
    10141 cagaagatac tcaaataata ggagctttag gagctgctgt aataggattt agataaaaac
    10201 atataaaaag aaaatgagaa gctgaattta ttataaataa attcagtttt ttattttatt
    10261 ttatttattt ataaaggaaa actttggtat aattgattta aatgattgta tatttgtaaa
    10321 tacttgatat ttagtcatat ataacattat aattttaaaa attagctcaa aataaggggg
    10381 agaaagcgtg aaaaaattta cttcaaaaaa agtaacaagg tttgttgcgc tgtttttaat
    10441 atctatttta gtaatgtcaa caattcctgt atcagctgac aatagcaata cattgaatca
    10501 gataaaaaaa gcagaataca gtgagacgta taaacaatat ctaaatgatg ctaaaaatgg
    10561 atgtacagaa aaatataatg ggattatacc aaatccatat cagttggaag gtactcaaat
    10621 ccaaagtaaa ggaagaacag ctccaacatc ttatgaccct agaaaattag gtcttatgac
    10681 atcaataaaa aatcaagagg atttaggaat ctgttgggat tttgctgcaa tggcaacctt
    10741 agaaagtttc ttaaagttaa ataattatgg agactatgat ttatcagaag aacacttaag
    10801 atggtgggct tcagatggtg aatatggatg gtctgtaaat gatatgaatg gtgctttaaa
    10861 ttatgaagct atgggatatt taacatcttg gtcaggtcct aaattagaaa aagatatccc
    10921 atacaatggt agagtatcta aagcacaagg agcaaaaaaa ccaactaata tgaatacagc
    10981 acctactgtt tttaatgtga cagatgctgt gtgtgtaagc aatgacataa attctacaaa
    11041 aaatgctata ttacagtatg gagctgtaac atctggttat tatgaagata ttaaatatca
    11101 aagtgatgac caaaattcat attattgtcc aacaaaaagt tttaatacaa atcatgctat
    11161 ttcaattgta ggttgggatg ataactattc taaagataat tttaatgcaa atattagacc
    11221 atcaaaaaat ggtgcttggt taataaaaaa tagctgggga gattataatt ctgagggtgg
    11281 atatttctgg atatcttatg aagacaagac acttatgtct gatatagata atttttcaat
    11341 caaaggtggt aaaaaaccaa atgatgatga gaagatgtat caacatgact atgcaagtat
    11401 tgtaccttta atttcaaaaa agataacagc tgcaaatgta tttgatttca atagaggcga
    11461 tgaaactcta aaatctgtaa tgttcttaac tgaaagtata ggagctaagt atgaagtata
    11521 ttatgctcca gtagtaaatg gtatacctca agaaaacaat atgaaaaaat taaaagaagg
    11581 tactgcccaa tattcaggat acataacagt tccaattgat tcttttgata taccagaagg
    11641 aaagggtgca attgtagtca gtatagaggg gaaaaatgga gagtcaacta taggttctga
    11701 gtcaaatgta ccaggatatg atacatttaa agcaaaagct aatttaggtg aaagttatat
    11761 catagataat actggaaaat tctttgatat aaatagagat agtaacttct atccgtgtaa
    11821 ttttactata aaagctgtta cagaaaagtc ttctggtgag agtatcccaa atgagtcttt
    11881 aattggtagt gatagatatg aaactgctat caaagttagt caaaatggtt tcaattcttc
    11941 agaaaatgta gttttagtaa atggcagttc aatagtagat gcattggcag caactccttt
    12001 tacatctgct ataaattcac caatattatt gacacaaaaa gaagctttaa attcaaaaac
    12061 taaagctgag atacagagat taggtgctaa gaaagtatac ctaataggtg gagaaaattc
    12121 tataagtaaa gaaattgaac aacaattaaa aagcttaaat atatcgatag agagaatatc
    12181 aggaagtgat agatacaaga caagtttatt attagctcaa aagttaaatg gtataaaaaa
    12241 tgtatctcaa atagcagttg taaatggagt gaaaggatta gctgatgcaa ttagtgtagg
    12301 cgctgcagca gcagaaaata acataccaat catacttgca aatgaaaaga gcgaattgca
    12361 aggagctgat gaatttctaa attcattaaa tatagagaaa tcttatatta ttggaggaac
    12421 agcatcccta tcaaacaatc tagaaagtaa gttaaaaaat ccaactagat tatctggtag
    12481 tagtagagac gaaactaatt caaagataat agataatttt tataaaaaag atactttaaa
    12541 aaatgcattt gtagttaaaa atggaatcaa gaatcaaaat gatttaatag atggattggc
    12601 agttggtcct ttaggagcaa aaactgggtc accagtaatt ttagttggtg ataaattagc
    12661 tgatagccaa aaagaagttc ttaaaaataa gactttagaa aaagtaactc aagttggtgg
    12721 aggagcaaat aaaaatgcat ttaaagagtt agtaaaatta aaaagtgcta aatagagtac
    12781 ttaagtatta acatatatta gtgtgtatta gtaacttatc ttaataaaag ctgaaaataa
    12841 ttacttcaaa ttattgataa ataagataat caatgattgt aaagttttgt tttcagcttt
    12901 aaatttatgt agtataagtt taaaaacata aaaaagggtt actttatata gaaatataga
    12961 aaatcttaca ttttatatat aaataaccca tatttaatta actttttata gtgttctaat
    13021 agatattatt gaacttaatg gtaaatataa tgtgtaagtt tcatttaaag ttggattaga
    13081 ttcatctata tatcttgagc aaagtgtaat tgataagcta tctgcttcta taatttcacc
    13141 atatagagga caactgctaa agtaagaatg tacttcaaca tatttattta agttttcttg
    13201 aacataatcg taaaaacggt tttttgtagt agtagccata aaatcaactc ctttattttt
    13261 tattaaagtt gaaactttta aaaagataaa tatgattact tctattagaa actaagttaa
    13321 aaaataagca aatagatatg aaaattagaa taatatatta tttatatctt aattataaca
    13381 ctagataata aaaaatgcta tataaaattc agaattttcg aaagttttta agcttatttt
    13441 taaatatact aataatacta ttgacattag atagaaaaag tattatattg actatataaa
    13501 ttattttagt caaactggag ggaaaagatg cctaaatcat attctgataa agaaagagag
    13561 tatataataa aaagacttaa agaagaagca agattgtgta tggagcaata tggtattaga
    13621 aaaactactg ttgatgagct tgtaaaacgg gtaaaaatac caaaaggaac tttttatcta
    13681 ttttttcaat caaaagaatt actctttttt gaggtattaa gagatataca tgactctata
    13741 caaaaagaaa tcttatatga gataaataga gtagatgaaa gtattacatg tgaacaattg
    13801 acagatatat ttatgaaatt ctataggatg gttgatagta cttcaatttt aaatctcatg
    13861 ataaatggag aatttgagat attggtgaga aagttaccag attctataat tgaagaatac
    13921 tttagacatg atgactttga aattggagag attatatctt gcataccaaa tgcaaaaaat
    13981 aaagacatag aaagctttag tggagcattt agagcagttt ttcttaccat gctatataag
    14041 cgcgaggttg gaagtaattg ttttgaagat gctttaagat taatgataaa cggattagtt
    14101 atacaactta tggaatagaa tttaaatttt gtttgctaat aacttttatt aaaaattatt
    14161 aacaaacaaa aaaattatat tttattgacc atatagtcaa aatagtcaaa aatttgaaag
    14221 ggtgatattg aatgattaaa gttgatgatt tatcatttag ttatacagat agagattttt
    14281 tacaaaatat taactttgaa gtaggaaaag gggaaatact aggattttta ggaccatcag
    14341 gtgcaggaaa atctacatta caaaagattc taattggaat gataactaat tatggaggaa
    14401 gtgtcattgt aaatggagta gagagtaaaa gacactcaaa taaattttat gaaaatatag
    14461 gagttgattt tgaatttcct agtttatatg aaaagttgac tgcaatagaa aatttaaaat
    14521 attttgggtc tctatattct aaaaaactac tatctattga tgagttatta aaatcagtag
    14581 gactagaaaa tgaatcaaat aaaagggtat ctgagtattc aaaaggtatg aaatctcgat
    14641 taaattttat aaaagcttta ttacataatc cagatatttt atttttagat gaaccaacaa
    14701 gtggtcttga cccatcaaat agcaaggtta tgaaagatat aattttatca gaaaaatcga
    14761 aaggtaagac tattatttta acaactcata acatgttaga tgcaacagag ctttgtgaca
    14821 gagtagcgtt cattgtaaat ggtaaaatat ctgctttaga tacaccacat aatcttatta
    14881 tgtcaaaagg agctattaaa gttagatata cttactttga taatggagaa aaaacttctg
    14941 aatgttttct gaacaatact gctaatgata aaaatttgaa tatgcttatt gagaaaaata
    15001 aacttttatc aatacatagt agtgaaccaa cattaaatga tatttttatt gagataacag
    15061 ggaggaattt acaatgaggc taaaaaatct tattttagga gatataaagt ttcaatttaa
    15121 gtatggtttt tattttttat atcttttttt aagtattata tatatttgta ttatcaatgt
    15181 atttccaact tttatgagag aaaaaatagc tataattatg atttattctg acccagcagc
    15241 aatgggattg ttttttatgg gagctattgt acttcttgag aaaagtcaaa gggttttaaa
    15301 ttccttagct gtatctccag taaaagtatc tgagtatatt ttatcaaagg taatttcatt
    15361 aggagtaata tctagtattg tagctatgtt tattgctatt acattaaatt tagataatat
    15421 tataatatca actataggta cctttttttc ttctattata ttttctttgc ttggattgat
    15481 aattgcaagt aaagcatcta gtttgaatca gtttattgtt ttaagtattc ctattgagat
    15541 tatatgcttt attccaccaa tactgaatgt acttcttgac acaaaatcat atgcaaattt
    15601 gtaccctttt aatatatgta tttctcttat tagtggagat aaaaatttta taatgattaa
    15661 tattttaatt ttaatatcaa ttataataat aatttatttt ataacttatt attttatttg
    15721 tagcagttgg aaaaaggtag gtggagtaaa actatgataa agattataaa tgcgtttaaa
    15781 caagagtttg aacaaattaa gagagatgct atgcttttta tagtatgtgt ttctccaata
    15841 ttatgtggag tatttataaa atttggaata ccattaatac agaatatatc acttaacaag
    15901 ttttattatc aattaaattt agagccgtat ttcttgatgt ttgatttact tttagctttt
    15961 attacacctt ttatgttctt ttttgcttct acaatggtca tattgggaga aattgatgac
    16021 agcatttcaa gatatttaat agtaactccg cttggtaaaa ctggttatct tatttcacga
    16081 tttggaatac caggtatctt agcatttatt attactatga ttctacttat ctttttttct
    16141 ctaactaaaa tttctctctt gttaaactta tcaatttctt tattagtttt attacaagga
    16201 gttattatat caatattagt gatttcttta tcatcaaata aactagaagg aatggtaatt
    16261 acgaaattct caggtgtttt tatgatgggt attttagcac cattttttat tttaaataaa
    16321 gcacaatata ttctgttctt cttaccaact ttttggatat cgaaggcatt taaggaagat
    16381 aattatgtct atatgtttat ttcaattgtt atatcattaa tatggatttt attattattt
    16441 aaaaagttta gtaaaaaaat agttaaataa gaaaatttaa tatataaatg taaggttgac
    16501 ttgacagtaa tgttgaaaaa tgttacattt aagatgtaaa gttaacctta catgaatgga
    16561 gcaaatatga aaaataaaat aaagatatta agagaaaaat taggattgac acaagaacaa
    16621 ctagggagat tagttggaac atctagacag gctataaatg ctatagaaac tggtaaaaat
    16681 gaaccttcaa tatggttggc atatgatatt tcaagaattt ttaatgaacc aattgaaagt
    16741 gtatttttat ttgaagaaag tgaaagaaaa tcaagagcac agataagtag gggagaatat
    16801 tatggctata agaaagataa gaacatttga tgatgaaatt ttaagaaaaa agagtaagta
    16861 tgtagaaaac gtagataata agataagaga aatattaaat gacatggcag agaccatgta
    16921 caatactcca aatggaggag gattagctgc atgccaagta ggagtattaa agcgattagt
    16981 tgttatagat ttaggagaag gacttattaa gcttgttaat cctgaaatta ttgaacaaga
    17041 aggggaacaa attgttgttg aaggatgttt aagttttcct gaagtatggg gtaaattaaa
    17101 aagaccaaaa aaagttacag tgcaagctct aaacgaatac ggtgagaaaa tagaaattaa
    17161 aggttcaggt tttatggcaa aatgtctttg tcatgagata gaccatttaa atggtatagt
    17221 ttttacagat aaaattattg aacatgtaaa attgtaagat agattggtta ttgaatttat
    17281 aaaatatttt atagtaagga gttaaattat gagattatgg cataaggatt taattgatgt
    17341 attacctaaa aatcaattag taagtcaatg gagagagcta cttgctataa aaggttctat
    17401 agataaaaaa ggtactccaa accatctatt agtgaataaa gtattgaatt atagtataga
    17461 tgaatttaaa ttttatacaa aaattgtaca tgatgaaatg ttaaaaagaa attataaacc
    17521 taatgaactt aaatatacaa gtatattaaa atggaaaaat agaaattttg caaatgatat
    17581 atctaatgaa catagtttaa atttagaaaa tttatatgat gattggcata ataaaatgta
    17641 tttaaagcaa tgcttatata atttagaaga aaaagcaaca tgtggaggaa taccaataaa
    17701 tgaatggaat atattacttt gtaaatatag taaagattat gaattgtggt ctggaaatat
    17761 catgttttaa ttactataga ttaacattat agtattattg tatataaaga ggtgattatt
    17821 tgtataataa aataaaatat attccaataa attgtgaaat agcttgtaat aaattaaaaa
    17881 ggagtatgcc atataaatgg gatttaaata tttatcgtgg atgtgagcat ggatgtaaat
    17941 attgttatgc tatttactct cataagtaca tcaactccaa taattatttt gaagagattt
    18001 atgtaaaaac aaatatagta gaaaaacttg agagacaact taaaagcagt aaatggaaga
    18061 aagaagtaat caatatagga ggagttacag atagttatca accaatagaa gctgactata
    18121 aaattatgcc agaaatatta aacctgctaa taaaatacaa gacaccagct attatttcta
    18181 caaagtcaga tttaatttta agagattacg atttaattga taagctatct aggattacat
    18241 atatcaatgt agcatctaca attaccacag taaatgaaga tacacaaagg cttattgagc
    18301 caaatggtgt ggattcaatg agacgattta aaatgttaaa agaatttaga aaaactaacg
    18361 catcagttgg tctacatatt atgccaatta taccatatat tacagatgat tttgataata
    18421 taaattcgct atttagacat gcaaaagaat gtaatgtaca ttatgtttta cctgggactt
    18481 tatacttaag gggtataact agaggtgttt tttttgactt tgttaaaaaa gagtttcctg
    18541 aattatttga taaattatca atactatata gtgcaggttc acttaatagg gagtataaaa
    18601 atcaattgta taaaatggtt aatgaactta gatataagta ttctctatca agcagttact
    18661 ctaaaataat gaaggaaaag ttaaaaaact caggagatgt acagatatct ttttttgatt
    18721 agttttatat aaaaaaattt tttttactat gatgattaaa atttattaaa attaaaattt
    18781 attgacaaat ataaaattta aatatataat taattcataa aataaaaata tgaaaggatg
    18841 atgttgttcg gtgatatttg atatcataaa atcgttgata taagtattgc tggaaaagag
    18901 tgaataaaat caaatttaat aagcaaacaa agtaaagcta tagttttatt gttgtgctta
    18961 aaaatatttg gttctatttt actcttattt aaactcatct ttttgaagtt aaaccacaga
    19021 gtaaactctg tggttttttt attttaaaaa taaattttaa ggagtggtat gttttgttaa
    19081 acaaattatg tatgtattta gaaagaccag agctttataa acaaagtgaa attaattttt
    19141 gggatgatga gtatatttca aagcaattat taaaagcaca cttagacact aattttgaag
    19201 gagcaagtag aaattttaac tttatcgagg attctgtaaa ttggatagtt acagttgcaa
    19261 atccagctaa ttatcctaaa ttacttgatt taggttgtgg tccaggttta tatgcagaga
    19321 aatttgcaca aaaaggttat aaggtaactg gaattgattt ctcaaaacgt tctattaact
    19381 atgcacaaaa tagaaataag gagactaatt taaacataaa ttacttgttc caaagttatt
    19441 taaatatgaa ctataatgag gaatttgatt tggctacttt aatttattgt gattatggag
    19501 ctttgtcaac tgaaaataga aggttattaa tggaaaaaat ttatgatagt ttaaaacctg
    19561 gaggaaaatt aatattagat gtatttacaa taaataaata caataatttt gaggaaatta
    19621 aatattggga aataaatgaa gatggaggat tttggagtaa tgaaaaatat atgtgtctac
    19681 aagataattg taaatacaat gattataata cattagaaca aactcttgta ataaccgaaa
    19741 aagatgaaaa tgtattttat gtttggaatc actatttttc aaaagaaagt ttcttattag
    19801 aagttgaaaa tattggattt aagtctgttg agttttttag taatgttaag ggtgaagcat
    19861 attctgacga tagtatgact atgggattag ttttacaaaa ataataattt ttttaaaatg
    19921 aataaataaa aacttgaaac ctttaacaat aaaataacat aataaaagct tacatattga
    19981 aaaatggaaa cttttatgtt atttttagta cattacaaat ttgcttatat aaaaatcaat
    20041 acttgaatta ttatttttat gtgaaattta tctatagtat atttttataa acaagtaatg
    20101 ttattaaaat taagtatgta gttaaaagtg tatagcaaaa aggctgttat attaatgtta
    20161 gaggttcagg gaaaatatat aaagcaaagt atttacagat aatgtagatt gcacagctat
    20221 aagttagata atagaattat gtaatcaaga atttacaaca aagtataaga taaggataat
    20281 gctaaattgc catacaggtg ctagatgtgt aaatggattt aattaatact attgataaag
    20341 tgcaacaagc acataaacca attgatgaga ttattaaaac tataagagat atagttgaca
    20401 taattaaaat attggaactt gtttataatt ttaaatcaaa tcaataatga ttaagattaa
    20461 aataatatta aggcatcaat gttataagag tacaatataa ggagtactat atagtactcc
    20521 ttacttatac atattaggca ataggaaatt ttttcatagt taaattttca agtatttttt
    20581 aggaaacttt ataattgaga attaagggta tagtatgtga tgaacttact gaatttataa
    20641 ttaggttata taatggaata atcatcaata gttttacttt agggaaaata tatgcttaag
    20701 gaagtatagc ttactaatat tattaaaatg tatatttaaa atgataaaaa aagaattaga
    20761 caagtattta gtaaattgac tatgcaaaat tctatcaagc aggaacccta tgactttagt
    20821 catgggaggt tcagtaggta acttgttgaa ttaagtttat attatttaaa taaactactt
    20881 aatttagata atataaaaag tcagaatttt aagaatagag ctatataatc ttagctatta
    20941 ggagaattac tatgatagga atatatttta gtggaacagg aaattcaaga tactgtgtag
    21001 aaaaattttt acaagaatat gatataacag caaattctta ttctattgaa gataatgaac
    21061 ttttacagca catcaataat catgagaata ttatttttag ttatccggtg caatatagta
    21121 atgtgccaaa aatattgaaa gattttataa taaatcattc aactttgtgg aatggtaaac
    21181 gtgtttttat tattgcaact atggctctat ttagtggaga tggctctggt gtgttatcta
    21241 gaatattaaa aaaatacggt gctataactg ttggtggatt acatgtgaag atgccagata
    21301 gtataggaga tgaaaaggta ttaaaacatt ctttagagta taatagaaag cttgtaataa
    21361 aagcagaaaa gaaagtaact aaagctgcta aaaaactgaa acatgggtca ccaccaaaag
    21421 aagggttagg ttttttgagt catattgtag ggttatttgg acaacgattg tattttatca
    21481 acaaaacaaa tatgtataca gataaactaa aaattaatac tgaggaatgt attgtatgtg
    21541 gtaaatgtgt taatttatgt ccaatgaaga atctagtaat taaaaattgt atgattgttg
    21601 caaatgggca atgtacaatg tgttatcgtt gtgtaaataa ttgtgctaaa aaagcaatta
    21661 cattgttagg taaaaaagtt gttgaacaga gtaatattaa aaaatatatg taagaaattt
    21721 aaagttttat tgaatgtaaa ttgatgtata ttttatgtta gaaagagagg ttaaataatg
    21781 gaatactaca tagttgattc atttgcaact aaactattta aaggaaatcc tgctggagtt
    21841 tgtgttcttg acagaagaat acctttagag ttaatgcaga aaatagcaga agaaaacaat
    21901 ttaccagaaa cagcatttgt agttaaaggt aaaggaaatt atgaattacg atggtttact
    21961 cctaaagcag aaattgattt atgtggtcat gcaactttag cagcagctta tgtaatatca
    22021 aattttattg atgttaatgt aaaaaggata gatttcttta ctcaaagtgg aaagcttgaa
    22081 gttacacgaa atggaaatct atatgaaatg atatttccag aaataatgcc tattgaaata
    22141 gagttatcac cacaacaagc taatttgata ggctgtgtac caagtgctgt ttattcttca
    22201 agagatttaa tcttattgct aaacagtgaa caagaagtta taaattataa acctaattac
    22261 gcacaattgc gtaaattgac agactggtta ggtataataa tcacagcaca aggaagtaat
    22321 acagattttg tatcaagata tttttgtcca gaattagatt cagaagaccc tgttactggt
    22381 tcatcacatt gtaatcttat tccatactgg tctgaaaagt tgggaaaaca caaaatggta
    22441 gctgctcaac tttctaatcg tggtggtata attcagtgtg aagtgttgaa ggataatact
    22501 gtgaaaattt ctggtgaagc agtcttgttt atgcagggaa caataaagat tgatatttaa
    22561 ataagtataa taactaattt attatgaaaa ataattaatt ttcttagtgt taacaataat
    22621 aaagtagagt taaaaaactt gatttcactt aaatcaatat gatagatgtt gatactaaga
    22681 ttgacaagca tgattaaaaa agataatatt taatctataa agataaaaac acagtctggt
    22741 tggtagtcca gacgcagcaa tagctgtcag taacctgcct ccttggttgt ccgttcttta
    22801 gaaagtaatt taaggaggaa ctagcaatgg acaaaattag tggaaaatta acagtcttat
    22861 ttgaagaacc attttgggta ggtatatttg aaagacaaga tggtaaaaaa tatgaagcat
    22921 gtagggtagt ttttggagca gaacctaaag aagtagaagt gtatgaattt atacttgaaa
    22981 gatttttctc attagatttt ggtagcatta aattagaaaa aaatgtgacc aaagacaaca
    23041 ttggatacaa aagaatgcag agaaaagtaa aaaaggaaca agaaaaagaa actataggga
    23101 ctaaggctca aaatgctctt aagcttcaat atgaagaaag aaaacaggat agaaaaaacc
    23161 tagctaaaaa tagaaaagaa gaagaaaaag aaagactatt taatttgaaa caagaaaaga
    23221 gaaaagctaa acataagggt cattaatttt aattaaatat ctttttaata attgctagaa
    23281 aaaggtgtat aaaattttta attttataca cctt
//
LOCUS       DAGQVA010000061        23251 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.061, whole genome shotgun sequence.
ACCESSION   DAGQVA010000061 DAGQVA010000000
VERSION     DAGQVA010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.061"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            445..1515
                     /locus_tag="MIV85_002681"
     CDS             445..1515
                     /locus_tag="MIV85_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962010.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            1499..2368
                     /locus_tag="MIV85_002682"
     CDS             1499..2368
                     /locus_tag="MIV85_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBY2962011.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2412..3272
                     /locus_tag="MIV85_002683"
     CDS             2412..3272
                     /locus_tag="MIV85_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBY2962012.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3303..4607
                     /locus_tag="MIV85_002684"
     CDS             3303..4607
                     /locus_tag="MIV85_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2962013.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4670..5932
                     /locus_tag="MIV85_002685"
     CDS             4670..5932
                     /locus_tag="MIV85_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBY2962014.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            6119..8089
                     /gene="uvrB"
                     /locus_tag="MIV85_002686"
     CDS             6119..8089
                     /gene="uvrB"
                     /locus_tag="MIV85_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBY2962015.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8108..10933
                     /gene="uvrA"
                     /locus_tag="MIV85_002687"
     CDS             8108..10933
                     /gene="uvrA"
                     /locus_tag="MIV85_002687"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBY2962016.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            11192..13009
                     /gene="uvrC"
                     /locus_tag="MIV85_002688"
     CDS             11192..13009
                     /gene="uvrC"
                     /locus_tag="MIV85_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBY2962017.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            13009..13938
                     /locus_tag="MIV85_002689"
     CDS             13009..13938
                     /locus_tag="MIV85_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBY2962018.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14152..15948
                     /locus_tag="MIV85_002690"
     CDS             14152..15948
                     /locus_tag="MIV85_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBY2962019.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(16088..17869)
                     /locus_tag="MIV85_002691"
     CDS             complement(16088..17869)
                     /locus_tag="MIV85_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBY2962020.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(17892..19778)
                     /locus_tag="MIV85_002692"
     CDS             complement(17892..19778)
                     /locus_tag="MIV85_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBY2962021.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(19795..20292)
                     /locus_tag="MIV85_002693"
     CDS             complement(19795..20292)
                     /locus_tag="MIV85_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBY2962022.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(20610..22091)
                     /gene="cls"
                     /locus_tag="MIV85_002694"
     CDS             complement(20610..22091)
                     /gene="cls"
                     /locus_tag="MIV85_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBY2962023.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSIFSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            22409..23179
                     /locus_tag="MIV85_002695"
     CDS             22409..23179
                     /locus_tag="MIV85_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBY2962024.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
BASE COUNT         8912 a         3088 c         3902 g         7349 t
ORIGIN      
        1 gggtaaattt ataaaaatta aaaaattttt attttttatg tttaaacctt gtaaatttgg
       61 gacataatat aattgtaaaa cttaatatag caaaaataaa ttactcaatc tcccccactt
      121 aaagacctct atcccccata gaggtctttt ttactttcaa atcaaattat ataaaaaata
      181 aatagtttta tatgactctt cataaattaa aattacattg tgatagcaaa caatgaatat
      241 gaaaaatata gaaaattata gctaacataa gctgtatatc atcttaacct cagtatattt
      301 aacaaaaaat gtttataatt taacctttat tttaataagt ttaccatata ttcactttgt
      361 cttaatatat cctttacaaa ttaagagtat tattaatcta taagtaaatc gtagaattaa
      421 attaaatatt ttgggaggat aaaaatggca gatataagac tagaaaatgt aacaaaatct
      481 tataataaaa aaaatacagt tatagaaaat ttaaatctta ctatagaaga tggttctttt
      541 acagtattgg taggcccaag tggatgtggt aaatctacta cgttaagaat gattgcaggt
      601 cttgaagata taacttcagg taggttgaag attgaagaaa atgatgttac aaaaacggat
      661 gctagtaaaa gggatatagc tatggtattt caaaattatg cattatatcc acatatgact
      721 gttagagaaa acatagaatt tggtcttaaa aacaaaaaag tagaaaaaga aaaaagagaa
      781 aaacttataa cagaagttat tgatgtagta ggattgagag aatatttaaa tgtgaaacca
      841 ggcaacttat ctggaggtca aagacaaaga gtggcacttg ctagagctat ggttaaaaat
      901 ccaaaggtat ttttaatgga tgaaccattg tcaaatttag atgctaaatt aagaaatcaa
      961 atgagaacag aattaataca attacatcaa aaactaaagt ctacatttgt ttatgtaact
     1021 catgaccagg ttgaggcaat gtcaatggca gataagatag ttataatgaa caaaggaaag
     1081 ataatgcaaa taggttctcc aaagaagata tatcaaaatc ctaaaaattt atttgtagct
     1141 caatttatag ggagtccttg tatgaacata ctagatataa aaaatgatat taaatttgga
     1201 ttcagaccag aaaaagcaac actagagagt ataaacatag atggaaaaaa tgatgatgta
     1261 tttagtctat ttggaaaagt tgtaactaaa gaagtgttgg gaaatgaaac tatatattgt
     1321 ttatctgttc ttaatagaga gataagagtc aaaacagaaa atgatatatt tgatattgga
     1381 agaactttaa gaataagtgt attagaaaaa gatttatatt attttgataa aaatggagaa
     1441 agaatagaag atgtaaaagt atgtaaaagt atgtattcta aaattaaagg agatatttat
     1501 gaaaaagcaa tttaataaag catatttata tataacacct gctattatag gaactttatt
     1561 gtttatagtc tatccaataa ttaagacgat atctctaagc ttcaaatctg gtagtcttct
     1621 tagttcaacc tttgaaaatg taggcttaaa caattataca gaacttttaa agaatccaga
     1681 gtttatacaa actataacaa acactgcaat ttatactttt tttatggtga ctatatctat
     1741 atcactagcc atagtacttg ctgtttggct aaataaaaat tctataatac acaatttaac
     1801 gcaaagtata atctttacac cacatgtaat ttcactagta tctgtagctg tattgtggct
     1861 ttggattatg gagccacaat atggcttttt aaactggata ctatcgacat tacatttacc
     1921 aacatcaaag tggctttcaa gtgaaagttc agctttaatg tcactaattc taataggaat
     1981 atggaagact cttggatata atatcttaat agtgttatca ggtcttaaat ccataccaaa
     2041 ctatatatat gaagcatcta aattagataa tgcaaacaaa ataacgaatt tctttaaagt
     2101 gacattgcca ctattatcac caacaatatt ttttcttatg ataacaacaa caactgcatc
     2161 ttttcaagta tttgatgaga taagtataat gacacaaggt gggccagtgg gttcaactaa
     2221 catgttatct tattatatat atgagtctgg atttatatac tatgacatag ggcaagcgag
     2281 tgcagcgagt atgtttttgt tagctatagt tatgattgct acatatgcta actttagact
     2341 cttatcaaag aaagttcatt atcaataaag aaaaagtaga tattataagg tttatccaaa
     2401 aggaggagac aatggatatt atacaaccta tcaaaaaaga caaagttgat ataaaaaaaa
     2461 tagcatcaaa atcaatagaa atattaattc tattactttt atctgcaata tttatattcc
     2521 cttttatatg gatgctatct acatccttta aaaatccaca agaaatgatg caattaccgc
     2581 ccactattat accaaatgat atagtgttag aaaattatag tacagcatgg cattcaggtc
     2641 cattttttag atatttgcta aacagtgtat ttgtaacagg aagtgtttta attgtacaat
     2701 ttttagttat ggttccagca gcatatgcat tttctaagat taaatttaaa ggtgaaaaaa
     2761 tgctatttgg gcttttgctt gtaggactta tgattccacc acaagtaact tttctaccag
     2821 tctatatgat gatgagtaag tttggattta taaatactta tgttccactt ataattccat
     2881 ttatgacatc ttcatttggg atatttctgc ttagacagaa ttttatgcag atttcagatg
     2941 aaattattga agcagctaaa ctagataatg cttctgactt aaaaataatg tttagaataa
     3001 tggttcctat ggcaaaacca gcagtaataa catttatatt atttaatttt atataccatt
     3061 ggaataatta tttctggccc ttagtaatga caaatacaga tgcaataaga actttaccaa
     3121 taggagttgc gctccttaaa tcttcagaag gaattactgc atggaatgta ataatggcag
     3181 gaaatataat tctaatttta ccaataattc ttgtttatat atttgcgaat aaaaaagtaa
     3241 aagaagcttt tatgtattca ggaataaaat aaaaaattaa agactaaatt tggaggatga
     3301 aaatgaagct taaaagaaaa ttagcaacag gattagcaat aacattatta ttaggttctt
     3361 tagttgggtg ttcaaattct aatgatgcaa atgcatctaa aggagaaaag actgatagca
     3421 atattacgaa gatagatttc tgggctcctt taggtggaac taatggagaa actgctcaaa
     3481 aaatggttga ccaatttaat agtgaacata aggatgtaca agtaaatatg ttaaaacaga
     3541 aagattacta tgaaaatgca acaaaactac aggcagcctt aacatctaaa gaccaaccag
     3601 atgtaacatt attagaaata actcaaacag gtacattcgc atcagcaggt gctttagtag
     3661 atatgagtaa atattttgat aaaacatatc aagaaagatt cttttctggt cttttaacaa
     3721 attcatatta tgaggataag tttgttggta tgccatttaa tagaagtaca ccaatattat
     3781 acataaataa agatatggca actaaagcag gtcttgaccc ttcaggtcca aaatcatggg
     3841 aagagcttaa ggattatgct agtaaaatga caaataaatc agaagatact tatggttttg
     3901 aaacaccaat agatatttgg ttctatgaag ctatggtaat gcaaagtgga ggagaaataa
     3961 ctaatggtaa aaaagtagca tttaataatg aggcaggaca agcaccagtt aagttctggc
     4021 aagatatgat gaaagctgga ataatgaaaa tgcctcctgg agaagattat aatgcctggg
     4081 acgtagcaaa acaagatttt gtaaatggta aagtaggtat gatatttaca tcaacagcag
     4141 atttagcagg acttatgcaa caaacagaag gtaagtttga aatatcaaca gcattcttac
     4201 caaaaaatca aaaatacgca actcctacag gtggagctaa tctagttatg cttgaaggtg
     4261 gaacagataa agaaaaagaa gcaagtgcag aatttataga atggatgaca caaacagata
     4321 aaatcgttca gtttagttca tcaacaggat acttaccaac aactgaagat gcaacaaact
     4381 cagaaaagtt acaaacatta tataaagaaa aacctcaata taaggttgca actgaccaat
     4441 tacaatatgc tgttgcactt ccaatgttaa atggatacaa ggaagcaact gataagctaa
     4501 tggatgagat taaaaagggg cttactgatt taaatgcaaa tccaaaagat gtagtaagca
     4561 aaggaacttc tgcaatgcaa gcagtaatag ataaaacaaa taaataatta tatagacttg
     4621 taagttgatt aaaagtattc aataatatat aaatgaagag gtaatgtaaa tgacaaaggt
     4681 tatagtatta tcagtagatt ctttatttga aaaagacttg gaatttgtaa aaaatctacc
     4741 aaactttaaa tctatactag aaaactgctc catagtaaaa aatataaatt gtgtttatcc
     4801 cactctgaca tatccgtgtc atactagtat ggttacagga gtatatccta aaaaacatgg
     4861 tatatatcat aatgaaaaat ttgacccaaa taaagaaaat aaagactggt actggtactc
     4921 aaaggacata aaagcaaaaa ctattataga tgtagcaaaa gaaaataatc taactacctc
     4981 tagtgtatta tggcctgtaa tgggagcaaa tccaaatata gattataata ttgcagaaat
     5041 atgggctcct agtagagaag atgacccaag agaaactttt gaacgaagtt ccagtaaggt
     5101 tataatggac ggtatttaca atagacattg tcattatatc gattggaaat tagaacccaa
     5161 catggattta tttggagtaa actgttcagt agatataata aaggaatata aaccagattt
     5221 aatgctaata catttagcta cattggacca tacacgacac aattatggct tatttaatga
     5281 cgaagtagat aaagcattaa aaatgaatga taaatggtta ggagatatta ttcaggctac
     5341 aaaggatgca ggtacataca aagatacaaa ttttataata cttggggacc atggtcatct
     5401 tagagttgat aaagttataa atccaaatgt cttgcttaaa tcaaatggat ttataaaagt
     5461 tgaaaatgga gaagttaagg attttgatgc ctatgtaaat tcttctggaa tatcagctca
     5521 aataatagta aataacttag ataggttaac agaattaaga gaactgcttg aagaatttaa
     5581 agaagaatta ttcatagaga atatttttac caaagaggaa gcatctaacc ttggtcttga
     5641 aggtgatttt gaaatggtaa ttgaaggtct tgaaggaatt tcatttggaa atgatttcga
     5701 aggaagtatt ataaaagatt cagatataaa agattacaag tttgctgttg cgacacatgg
     5761 tcatttacct actaaaggta atagacctcc atttatagct tttggaccaa atattaaagg
     5821 tggtgtggtt atagaagaag gagacctgag agcacatgca gcaactatat taaaaatgtt
     5881 taatttaaaa ttagatggag ttgaaaaaga agcatttgat tttattatgt aagttgaata
     5941 aagtatttat tttccatgaa ttatagactt ctattgcaaa gatagaagtc tttttttatg
     6001 ttttagattt aagtaaaatt taaatgggta aaatatttaa aataacttaa acaattttat
     6061 aaaggtatga tataataata catgtcagga actaatgttc gaaaaaagga gtgatactat
     6121 ggattttaaa ataaaatcag acttcaaacc tacaggtgac caaccagaag ctattaaatc
     6181 aatagtggat tctataaata gaaatgagaa attttcgaca ttattaggtg taacgggttc
     6241 aggaaaaaca ttcacaatgg caaatatcat tcaacaagtt aagaaaccta ccctaataat
     6301 ggctcataat aaaactctag cagcacaact ttacagtgag tttaaagaat ttttcccaga
     6361 caatgcagtt gaatactttg taagttacta tgattattat caaccagaag catatgtagc
     6421 tcacagtgac acttatatag aaaaagatgc aagcataaat gatgaaatag ataaacttcg
     6481 acattctgct acagcatcta ttttagagag aagagatact ataataatat catctgtatc
     6541 ttgtatatat ggacttggtg acccaaaaga ctataaagaa cttatgttat ctataagacc
     6601 aggtatgcaa agagacagag atgatgtaat aaaaaggtta atagagatac aatacgaaag
     6661 aaatgacata aactttacac gaggtacctt tagagttaga ggagatatac tagaaatatt
     6721 cccagctagt aatgatgaaa aagcaataag aatagaattt tttggtgatg aggtagatag
     6781 aataacagaa attgattatg taacagggaa gattgttggt actagaaatc atgttgttat
     6841 attcccagca tctcactatg taacaacgcc agaaagaatt gaaaaggcaa ttgtagaaat
     6901 agaaaacgag cttcaagaac aaattaaatt tttcaaggaa aatgataggc tattagaagc
     6961 acaaagaatt gaacaaagaa ctaagtatga tatagaaatg ttaaaggaaa taggattttg
     7021 tcaggggata gagaactatt ctagacatat tacaggaagg tcagaaggag aaagaccata
     7081 tactttaatg gatttcttcc cagatgatta tttgataatt gtagatgagg cacatgtcac
     7141 tataccacaa gtaagaggta tgtatgcagg agacaggtct agaaaaacat cacttataga
     7201 gaatggtttt agattacctt ctgcacttga caatagacca ttaaattttc aagaatttga
     7261 aggaaatata aatcaaatgt tgtttgtaag tgctacacca gggccttatg aaattcaaca
     7321 ctcagagaca atagcagaac agataataag accaactggc cttttagacc caattgtaga
     7381 agtaagacct ataaataatc aaatagatga tttggtagga gaaataacta aaactataga
     7441 aaaaaatgaa agagtgctta taaccacttt aactaaaaaa atgagtgagg acttgactaa
     7501 ctatcttaaa gaaataggga taaaagttaa atatttacac tcagatatag ttacattaga
     7561 aagaacagaa ataataagag atttaagatt agggaagttt gatgtccttg taggaataaa
     7621 cttacttaga gaaggattgg atataccaga agtttcactt atagcaattt tagatgcaga
     7681 caaagaaggt ttcttacgtt ccgaaacagc tttaatacag actattggac gtgcagctag
     7741 aaatgaaaat ggaagagtaa ttatgtatgc agacaggata actgactcaa tgcaaaatgc
     7801 tattgatgaa acaaagagaa gaagagatat acaaaattta tataatgaag agcacaatat
     7861 cattcctaaa actatacaga aaaatataag agatagtata gaagctacta aggttgcaga
     7921 ggaagaagtt gtatatggaa tatctgatac agatgataaa gacgaaataa gagctaatat
     7981 agataaatta aaatcagaga tgatggaagc tgctcaaaac ttacaatttg aaagagcagc
     8041 agaacttaga gataaagtga aacaattaga agaaaaattg gaaaaataga aaggtaaaaa
     8101 caacattatg gaagataaaa ttataataag aggagcaaaa gaacataatt taaaaaatat
     8161 agatttagaa ttaccaagag ataaatttat tgtttttaca ggtttgtcag ggtctgggaa
     8221 gtcttctttg gcatttgata caatatatgc agaaggacag agaagatatg tagaaagtct
     8281 atctgcttat gcaagacaat ttttaggtca gatggaaaag ccaaatgtag aatatataga
     8341 gggtttatca ccagctatct caattgacca gaagactacc tcaaaaaacc cacgttctac
     8401 ggttggaaca gtaacagaaa tatatgatta tttgagacta ttatttgcaa gagtaggaga
     8461 tgtgtattgc cctacatgtg gtgaaaaaat aagtcagatg actattcaag aaatagttga
     8521 taaaatgcta gattttccag atagaacgaa attacaaatt ctttcaccaa ttgttagagg
     8581 acaaaaaggt acacataaaa aagtctttga taatatcaaa aaagaaggat ttgtaagagt
     8641 tagagttaat ggtgaaaact atgaagttag tgatgatata atcttaaata aaaatcaaaa
     8701 acataatata gaagttgtag tggacagaat agtaattaaa gatggaatag aatcaagact
     8761 agcagattca attgaaactg cagttaagct atctgatggt cttgtaatag cccaaataat
     8821 agatggagaa gaaattcttt tttcaactaa atttgcatgc ccagaacatg gaattggcat
     8881 agaagaatta tctccaagaa tgttttcatt taatgctccc tttggtgctt gtgatgtttg
     8941 taatggtctt ggggaaagta aagaagttga cccagaatta gtagtaccaa acaaagattt
     9001 atcaataaaa caaggtgcag tggcagcatg gggttcaaca ggtgttaatg atgacactta
     9061 ttacagtaaa atgataaaaa gtttagcaga gcattttaat gtatctttga caacaccgtt
     9121 taaagattta ccagatgatt ttgtggagga attactttat ggtaaagata atataattgt
     9181 agagtttact tatgagtcaa aatttggagg aactagaaat tataaatcat actttgaagg
     9241 tgtaatagta aacttagaga gaagatatag agaaactaat tcagattaca tgagagataa
     9301 gattgaagaa tacatggcag agagaccatg tccaaagtgt aaagggatga gacttaaaaa
     9361 ggaagtttta tctgttttag ttgatggaaa aaatataatg gaagttacaa acttatctgt
     9421 aaatgaattg attgacttta tggaaaatat aaatcttaca gaaaaacaga gatttatagc
     9481 tcatgagatt ataaaagaga taaaaggaag agctatgttc ttaagagatg taggtcttga
     9541 ttatttaaat ttatcaagaa aagctggaac tttatcagga ggagaagcgc aacgtataag
     9601 attagctact caaataggtt ctgcattggt tggagtttta tatgtacttg atgagccaag
     9661 tatagggctt caccaaagag ataatgatag gcttataact actcttagac atctaacaga
     9721 tttaggaaat accttaatcg ttgtagagca tgatgaagac acaatgagag aagctgatta
     9781 tgttatagac attggtccag gtgcaggtat acatggtggt gaaatagttg cacagggtac
     9841 tttagatgaa ataattgaaa atgagaactc aataacgggt caatatttaa gtggtaaaaa
     9901 acaaatattg cttcctgaga ctactagaga aggaaatgga agttttatag aaatagttaa
     9961 agcatcagaa aataatctga aaaatattga tgtaaagttc ccattaggta agtttacatg
    10021 cataacaggt gtttcaggtt ctggaaaaag tacattaata aacgatatac tttacaaagg
    10081 tgttgcaagt aaagtgaata gacttaagca aagagctggt aagcataagg agataaaagg
    10141 aattgaaagt atagataaag ttataaatat agaccaaagt cctattggaa gaacacctcg
    10201 ttcaaatcct gctacttata caggtgtatt tgattttata agagatattt ttgcatctac
    10261 taatgaagct aaagcaagag gttataaaaa aggtagattt agttttaatg taaaaggtgg
    10321 tagatgtgaa gcttgtaagg gtgatggaat aataaaaata gaaatgcatt tcttaccaga
    10381 tgtatatgtt ccttgtgaaa tttgtaaagg tgaaagatac aatagagaaa cattgcaagt
    10441 aaaatacaaa gataaaacta tatctgatat attagatatg aatgtggaag aagctgttga
    10501 gtttttcgaa aatataccaa atataaaaag aaaattagaa actttaatgg atgtaggact
    10561 ttcatatatt aaattaggac agccttcaac tcaattatca ggaggagaag cacaacgtat
    10621 aaaattagct gctgaactta gtaaaagacc aacaggaaag actttgtata tattagatga
    10681 acctactact ggacttcata tggcagatgt agacaagcta atccaagtat tacaaagact
    10741 agcagataca ggaaatacaa ttatagtcat agaacataat ttagatgtta taaagacttg
    10801 tgattatgta atagacttag gaccagaagg cggagataag ggtggaacta tagttgcaac
    10861 tggaacacca aaagaagtat ctaaagttga tggttcttat acaggtcaat tcttaaagaa
    10921 atatttttct taagttatat aaattgtgaa aaattttaga gcagatatac gataaactgt
    10981 tttgttataa gtaaattagt caaatataag ttgtaaatag taatacaaag taaagtccat
    11041 attactcttc atggttaaaa ttgttttcaa atcaattata gaagggaata tgggctttaa
    11101 cttgtttaaa gcactggaaa ttgtataact ttttaaaatt catattttag ggtataattt
    11161 tagtataaaa tttaatgttt tggagggcga gatgtttgat atacaagagc atttaaaaaa
    11221 attaccttct gagcccggag tatatttaat gaaagacaaa tacgaccata taatatatgt
    11281 gggaaaagcc atatctctaa aaaatagggt aaggcagtat tttcaatctt caaaaaacca
    11341 tacatctaaa gtaaaatcta tggttaagaa tatatataag tttgagtata ttataacgga
    11401 ttcagagtta gaggcattaa tacttgaatg taatttaata aaaagataca gaccaaagta
    11461 taatgtagtg cttagagatg ataaaactta tccatatata aaagtaacta cgaatgaaga
    11521 ttatccaaga atcttaaaag ttagaagagt tcttaaagat aaggcaaagt attttgggcc
    11581 ctataccaat ataactgctg tgaatgatac cttggagctt ataagtagta cgtatccaat
    11641 aagaagctgt aaaatagata tagataaagc aataaagaat aagacaagac cttgtttaaa
    11701 tctacacata aataaatgtt taggaccttg tacaggaaat gtttctaaag aagagtatgg
    11761 aaaaatgata gaagagatta taatgtgttt atctggtaaa gaagaaaaat tgatggaact
    11821 tttaaaggaa aaaatgaatg agagttctat gaactttaga tttgaagagg ctgctgtata
    11881 tagggataag ataaagagcc ttgaagagat gatacagaaa caaaaaatag atgctactgt
    11941 aagtgactta aaccaagatg tggttgcaat ggcaagagct cataatgaag cttgtgtcca
    12001 ggtatttttt ataagaaatg gtaagattgt aggtagggaa cattttatat tagaaggggt
    12061 aatggatagt ccaagagctt ctatattaag ttcatttgta aaacaatttt ataatgaaca
    12121 agagtatata cctaaagaat taattataga agatgagata gaagatagtt ctatattaga
    12181 agaatggctg tcatctaaaa aggggcaaaa agtaacaata agagttcctc aaaagggaga
    12241 gaagaaaagc ttagttgaaa tggttaggaa aaatgctgta gaatatcttg aaaaattttc
    12301 tgatatgaat aaaagaaaat atgaaaaaag tattggagca ttggaagaat taaagcaaat
    12361 attaaatcta gaaaagttgc caataagaat agaggcttat gatatatcaa atatacaagg
    12421 tgtagattcg attggttcta tggtagtgta tacgaatgct aaaaaagata agaaggaata
    12481 taggagatat aaaataaaga cagttattgg acctaatgat tatgattcta tggctgaaat
    12541 tgtagataga agattaaaac atggaaattt acctgacttg atattgttgg atggtggaaa
    12601 aggacaagtt agtgcagtaa aaaaagtact agaactcaat gatgtagata tacctctttg
    12661 gggaatgtac aaagatgata agcatagaac taaaggattg atatgcaaag aaaaagaaat
    12721 agaactagat aaaacaacta atttatatag atttattgct agtatacaag aagaagttca
    12781 taattatgca ataacatatc atagaagtct aagaaataaa gctttgacaa aatctatctt
    12841 agatgatata caaggaatag gtgaaaaaag aaagaaatca ttattaaatc actttaaaga
    12901 tgtagatgct ataaaaaaag ctactatgga agaactttta gaagtagatg gaatgaataa
    12961 aagcattgca gataatgttt ataatttttt tagaaaggaa gaaaattaat ggaaactagc
    13021 aataaagtat caataagaga gataataaaa gagttgaagt taaaagtagt atacatgcct
    13081 gatgatgtag attattatgt ctactctcaa gatataaata gaccaggatt acagtttgca
    13141 ggatattttg attattttgc atatgaaaga atacaaatag ttggaaagac agaatataat
    13201 ttttttggat taatggatag tcatattcgg gaagaagtac tagatagatt tttctcatat
    13261 gaaataccag cgttaataat ttctagagac ttggaaatca agccagatgt aattgaaaag
    13321 gctaaaaaat ataaaagaat acttttgagc acaaatagaa ataccactag acttataaat
    13381 agactgtcaa actatttgga taataagtta gcaccacaca caacaattca cggggtgcta
    13441 gtagatattt atggtatagg tgtactgata aaaggtgaaa gtagtatagg aaagtcggaa
    13501 acagcattag aattgattca aaggggtaat agattagttg cagatgatgc tgtagaaata
    13561 agaaaattag atgaaagtat gcttgtgggt cagtcacctg aactaataag acattttctt
    13621 gagataagag gaataggaat aatagatgtt agaagtttat atggagtagg ggcaatcaaa
    13681 aattctaaaa tgatagattt agtagttcat ttagaagctt gggatgaaac taagtattat
    13741 gatagactgg gactggataa agaatatgaa gaaatacttg gtgttaatgt agagaaatta
    13801 gttgtacctg ttaaacctgg aagaaatact gctatgatat tagaagtagc agcaatgaat
    13861 tttagacaaa gaggaatggg atacgatgca gctcaagaat ttactaaaaa attatcaaaa
    13921 ttaatcgata ctaagtagta ctgaataata gtgaactaca catcatttaa ttaaatattg
    13981 attaggatta tgtcctacac cttataaatt aaaatcaagt tgtatatata taatgtttat
    14041 taataagata tattatataa ggataattta aagtacagtg ttagattata ataatactag
    14101 attaatttta tatttgagtt tcattatata acaagaaagt tggaattttt tatgggaata
    14161 gaatatttta gtaaactttt agaaagtagt actgaaaaag aattgctctt aagtaaaaag
    14221 tcaaataaca taagtacagc aagattaata tcttttttga tagtgatagc agggtttgct
    14281 attggatttt acaataaaaa tatagtaggt atttttgttg gagttttatc aataataata
    14341 tttatagcac tcttagttat tcatagtaaa gtaaaagaag aagaaacata ttttaaaagt
    14401 aagagcgaag tattaaataa gtatattaag agatttggag atggttggaa ggaatttaaa
    14461 atagatggta aagaatactt aaaagatgaa aattcgcaag caaaagattt agacttattt
    14521 ggaagagcat cattgtatca atatatctgt gtagctaata catcttatgg gaaaaatttt
    14581 ttagccaaat atttgtggaa tgaaaatcca gatgagaatg taatcttaga aagacagaga
    14641 gctataaaag aacttttatc aaaagatgat ttttctattc atattcaaac actcagtaat
    14701 ataattggta aagagcaaaa aaacaattca gatagtagta tagaatcgtt tatagaatat
    14761 ggagaaaata agaatgtgta tataccaaaa tggatgcata tttttacttg gggtttacca
    14821 actgcaacaa tcttatcttt tatattttgt atgttaggat ttttacctgt tttacctgtt
    14881 tttttacttt ttataatcca gttagggttt agtggttttg gatatccaag acttatgcaa
    14941 actcttgctc cattattttc atttagtaga agtatacaag tatatgaaaa aatgtttgag
    15001 gttttagaaa aagagacgtt tgagagtgca tatttgaaag aattacaaga taaactttct
    15061 aagggaagtg gagtttcaag aggtgttaaa caattaaatt caataggaaa tgctgtaaac
    15121 ctaaggtata atcagatact atatataatt gcctgtggtg ttttgatgtg gaactatcat
    15181 tgtgcagaag ctttggagcg atggaaaggt atatatggaa atcaaattag agattggttt
    15241 gaatctattg gagaatttga agctctaata agtttaacag ttgtttctca tgtaaaggaa
    15301 aatacatgtt ttccagtaat aaaatatgaa gatactccaa gattgaaagt tgaagaggta
    15361 taccacccat taatagcaga aaaaagtgtc atagcaaatt cgatacaatt aaattctcag
    15421 acttgtatta tcacaggttc aaatatgtct ggaaagacaa catttttaag aagtatcggt
    15481 gtaaacttag tgctggcata tgcaggtgct ccagtatgcg ctaagagttt tgatgcgacc
    15541 tgtatggcta tatttacttc tatgagaata caagatgatg taagtcaagg aatatcaact
    15601 ttctatgctg agattcttag aataaaatca atgattcaat atagtttaaa agaactgcca
    15661 atgttggttc tagtagatga aatttttaag ggaactaact ctgctgatag aattattgga
    15721 gcaagtgagg cagtaaagaa attatcaaaa ccctgggtta taagtatggt gacaacacat
    15781 gactttgagc tatgtgacct ttcaggtagt ggagatgttg aagttgtaaa ctatcatttc
    15841 tcagagtact atgtagacga taaaattcat tttgactata agataaaaga tggaagatgt
    15901 aaaactacaa atgcaaaaca acttatgaga atggcaggta ttctttaatt aatagatagg
    15961 ttaattaaag aataagtcta tttagaaata taatttaatt tgtgaaatta ataaggattg
    16021 tcttaaatta cgtaaaagta ttttaagaca atcctttttt aagaataaat tttatatttt
    16081 gttatgacta cttagcttct tcacaagcac attcttgtgg acactctcca tagacacaac
    16141 tcttatcaaa gtaatgagta tgaaggtatt tatgggctac atcactattt ggttctccaa
    16201 agaagtcttt ataaatagct tgtaaatcag gattctcatg agatttacga atagccttat
    16261 ttctatctat ttcatataac gcatttgcac gtctatcaac tatttcagta ttaccatggt
    16321 gataaggttg accagcacct ccaacacatc caccaggaca tgccataact tctatgatat
    16381 ggtatttaca ttctccactt ctgaccttat ccataatctt tctagcgttt ttaagtgtat
    16441 ttacaataca cacattaact gtagttccat caacatctat acttgcttcc ctaattcctt
    16501 taagacctct aacattagtg aagtttacat tatctaaagt cttattagtt atcttctcat
    16561 atgaagtacg tagggcagct tctaaaactc caccacttgc tccaaatata gatgcagcac
    16621 ctgtagattt tcctagagga ttatcaaaat cttggtcttg aagattaggt aaatcgattg
    16681 cagcttcttt tatcatctta gctaactctc tagtagttat agaaaggtca acatctagta
    16741 ttccagattc acttaattct tctcttgaag cttcatattt tttagctaca caaggcatta
    16801 cagatacaac ataaagttct tcaggattga ttcctaatat tttaggtgca tagtagtttt
    16861 tagctataga accaaacata ccttgaggag acttacagct agatgctaag tttaacttgt
    16921 ctggataatt gtgctctaag aagtttaccc atgcaggaca acaacttgtt aatataggaa
    16981 gattttcacc tttttggatt ctttctataa attcagtagc ttcttccatt atagtaaaat
    17041 ctgcaccaaa gtttgtatca aatacatgtt caaatccaag tgcttttaaa gcagctacca
    17101 ttttccctgt agagattgac cctggttcta atccaaactc ttcaccaata gcaactctta
    17161 cagcaggagc aacttgcact actatagtct tttctttttt atttaaaaca tcccaaagtt
    17221 taggtacatt atctacttct gttaatgctc cagttggaca gacagatata cattgaccac
    17281 agaatgtaca ctctgtttca accatatcag agttaaagaa tgtactaact aaagtattaa
    17341 atccacgatt aactccagat aatgctccta ctgtttgtat gtcattacat acagtctcac
    17401 atcttctaca taatatacac ttagaatggt ctttaactaa agatttagta gaagtatctt
    17461 tacctgcaaa agatttagaa ccttgatatc ttatttttct tactcctaaa tcagcagcta
    17521 tagtctgtaa ttcacaatct ccattttttt cacagacaaa acaatcttgt ggatggtctg
    17581 ataacaataa ttcaacaata gttctacgag catttaatgc tttagcacta ttagtctgaa
    17641 ctttcatacc ttcctttata actgttccac aagctggaac taatcctctc tctgtctcaa
    17701 ccatacaaac acgacaagaa gcacaagtgt caagcttatc tatttcattc atatgtaaat
    17761 gacaaaggtt gtgtattttt atatttatta atttcgcagc atctaagata gaagttccac
    17821 taggtgctga aacgtgtttg ccattaatag ttaaattaac taaactcatt gttattcctc
    17881 ctccaaataa gttatttctt gattatagcg ttaaatgtac aattatctat acaagcacca
    17941 cattttagac acttagaagt atctattgta tgttgttcct taacagaacc tgttatacaa
    18001 ccagcaggac acactctaga acattttgta caacccttac agtcatctgt tataaagtaa
    18061 gaaagtaagt tctgacattt accagcagga catttcttat ctacaacatg agctatatac
    18121 tcatctttga aatattgaag agtacttaaa acagggtttg gagcagcttt accaagacca
    18181 cataatgaag cagtttgtat agtttcagca aggttttcta ggtcatctaa atcttgtaga
    18241 gtaccattac cttctgtaat tttagttaat atttctaata atcttgtagt acctatacga
    18301 caaggtgtac atttaccaca agattcttca acagtaaact caaggaagaa cttggctata
    18361 tctaccatac agtcagattc atcaagaaca agcataccac cagagcccat cattgaaccg
    18421 atagaactta atgaaccaaa gtctatagga gtgtctaaat gttcagttgg tatacatccg
    18481 ccagatggtc cacctgtttg aacagcctta aatttcttac cttcagggat tcccccacca
    18541 atttcaaata caatatctct taaagtagta cccattggaa cttcaacaag tcctacattt
    18601 tctacttttc caccaagagc aaagacttta gtaccactag aatcttcagt acctaagttg
    18661 gcaaaccaat ctccaccctt aagtataatt gcaggtatgt tagcaaaagt ctcaacgtta
    18721 tttaagcaag taggagattt ccatagacca ctcttagaag aactataagt tttcattcta
    18781 ggttcaccac gtctaccttc aattgaatgc attagcgctg taccttcacc acaaacgaaa
    18841 gcacctgcac catattttaa ttctaattta aagttaaatc cagtgcctaa gatattttcg
    18901 ccaagtaaac cgtatttttc agcttgagct atggctactt ttaatctttc tatagatttt
    18961 ggatattctg ctcttatgta tatgtatcct gtatcagaac ctatagcgta tccacatatt
    19021 gccatagctt ctagtacact atgagggtca ccttcaagta cagatctatc cataaatgca
    19081 cctgggtcac cttcatcagc attacataca acaaactttt tatctgttgg accagctgga
    19141 ttttttgaag cagcttccca tttagagcca gtagggaaac ctgcaccacc tctaccacga
    19201 aggccagaag tttttacctc tgcaataact tcttgaggag taagagaagt taaacatttg
    19261 cctagagcta aataaccatc attggcaata tattcttcta tactatctgg gtctataaga
    19321 ccacaatttt ttaaagctat acgtaactgt tttttgtaga aagacatttc ttcttgttct
    19381 tcaacttttt tacttaaaga ttcttcctca tataataatt cctcgacaac tgtatttcta
    19441 attaagtggc tttgaactat cttttcagca tcagatggct caacttttac gtagaaaacg
    19501 ttatcaggat aaacttttac aataggacct tgagcacaga aaccaaaaca acctgtcaaa
    19561 cgaacactaa ctttatcttg gattcctgat ttctttattt cattttctaa ttcactaact
    19621 atttctagac tgtttgaaga tgtacatcca gtatcacaac aaacaagtaa ttctcttctt
    19681 aatacatttt ccttagaata attttttctt aagctaagat taggtttcag ctcatcagct
    19741 aaaactttta attcatcaaa tgaatttact ttacgcatta tttattcacc cctcttaaca
    19801 attcaattct aattctctat aagtatctaa tatttcgctt acttggtcag gtttcacttt
    19861 accataaact ttaccattta cagtaacaac tggagctaaa ccacatgccc ccaaacatct
    19921 taaaccttct aaagaaaatt taaaatcact agtagtttct ccaactttta tgccaagctg
    19981 tttttcaaaa gcacttaaga ttttgtcagc accttttaca aaacatacag ttcctagaca
    20041 gacactgatt ttatacttac ctacaggttc tgtagtaaaa taagaataga atgtaacaac
    20101 cccatatacc tttgcaggag ctactccaag ttttctagca acatgaagtt gaacttcttt
    20161 tggaagatat ccaaatatac cttgggcttc atgtagaact tgtattaacg caccttcctt
    20221 tgttgcaaga gagtcaataa atatatctag ttcgtcaaat aattgcttgt tgtgtgaaat
    20281 aaaatcgcac ataacaaatc ccccttttct ttttaaagtt attatttttc ataaaataat
    20341 taaccatgag ttgaccccaa cattatgtgg gtgaacaaaa ccaaaacaat aaagaaagaa
    20401 taatatacaa caatttcttt atttataaaa acaatgcaaa aaagttacct attaaaaata
    20461 aaaactatac tagtctatta taatataaaa taattcagaa tagttaaaaa aaataaaaaa
    20521 aatgagctaa attcaataaa aaaaaaataa tacatataaa aaactttaaa aaataaacca
    20581 aaatgtaaaa tttttataaa ataaaagatt tataaaactg ctgataatag tcttgaaatt
    20641 gattccttga tttttatata agtagaccta gaattatata tatctaatgt tatttcctta
    20701 gaatttaaaa tatcattttc aaatataatt ctttgttcca atgctttttt tgaagagtac
    20761 ataaatgcat taacttcgaa attaagctca aaacttctga tatccatatt agctgttcct
    20821 atagagaata tagagtcatc tataactatt gtcttagcat gtaaaaatgc attttgacca
    20881 taagtataga ttttagctcc aaactttaaa agttctccag catatgaata tgatgcccag
    20941 tatacaaagg gatggtcagg tttagaagga atcataactc tcacatcaac accagataaa
    21001 caagctattt ttaaagtatc tataaaagtt gagtcaagta ttaaataagg actctgtatg
    21061 tatatatact ttctagcttt ctgaatcatt ttaaggtaac catatttaat ctcatcaagt
    21121 tctgatatat ctggaccact tgatactatc tgaatcccaa tattttcaga aggatgatta
    21181 gaatttgtat cttcttctat aaagtacttt tctaaatcta agtcttcttt agttgtatat
    21241 ctccaatcaa ggatgaatct catatttagg tcaattacgc aatcaccagt aagcttagta
    21301 tgtgtatctc tccatagacc aaattttgga tttctaccta aatattcatc accaacatta
    21361 tatccaccta caaatcctac cttaccatca atgacaacaa tttttcggtg atttctatag
    21421 tttaagttaa agtttacaat tttcaagaat gatgggaaga agcttccaac tttaacacca
    21481 ctttctttaa gtctggaaag tgtactattt tttagtgttc taccaccaac tgcatcaaat
    21541 aaaagtctta cttcaacacc ttctttagct ttgtctataa gaatgtctat tatttcagtt
    21601 ccgattttgt catctttgaa aatgtaaaat tgtatgttta tatatttttt agctttttta
    21661 agttcttcaa gaagactgtt aaaaaattga ctagattcag cataaatcca cacatcgtta
    21721 ttattggtat aatgagcatt atttgaatta gccaatgcat aaatcatatc cttatgttga
    21781 tgtatatctg aatcaatttc agatgtagat tggagtttaa cctgagtatc tagtatatta
    21841 cttttgatta tcttatcatc cttttctttc aatctaaaca tattgttttt tgaaatattt
    21901 ctgccaaaag ctatataaag tatgaatcca agagcaggaa tcaatactaa tataagaagc
    21961 catgttaaag ttgtatttat gtttcttttt tctctaaaga taaggtttag tataaccatg
    22021 aaattaatta tatatattgt agtaactgct atttcatata ttgacatttc gaaaaatgat
    22081 atatcaaaca taaaattccc tccttcaaat atttattaaa ataagtaatt atatataata
    22141 acacaaacat atatctatta tatataatac ctcaataatt aaaaagtaaa ataaataatc
    22201 aaaaggtaaa tttttcaaat tcaatataaa ttatttcgaa attaacaaag ttgttatata
    22261 ataaatagta taattatatg agacaagtat atataagtat atagtatatt ttttatgtta
    22321 ataaaattta ttatatatca tattgttatt atataattat tgccataaaa agacaaggga
    22381 aagtataatt tttaaggggg aaggatttat gagtaaagga ttcttgacac ctggggaaac
    22441 tgcacaagca actataagtg caggcattaa aaaagcaaat atttcgacac aaaacgcaat
    22501 tctattaggt ttatttggag gagcatttat aggttttggg gcattgggga gtatgatagt
    22561 tagtcaaact tttggcaaga tagacccagg ggtagctagc tttttaagtg ctatggtctt
    22621 tccagtaggt cttatgcttg tagtagtggc aggagcagaa ttattcactg gaaacacctt
    22681 aatggctatt gcacttatgg acaaaaaaat aacattagga aaaatgttaa gaaactgggg
    22741 actggtttat tttgcaaatt tagtaggttc aattttgcta gttgcacttg tgttttattc
    22801 ttctacattg acaggagatg cagctacaaa agctatagct gtggcagaag ctaaggttaa
    22861 ttcaactata gcatcaatgt ttttaaaagc aatactttgt aatattctag tcgttttagc
    22921 tgtatggatg gctacagcat ctcaagatat aatgtcaaaa ttggcttcat gttggacagt
    22981 aataatgcta tttgtattat gtggattcca acatagtgtt gcaaacatgt tttttatacc
    23041 aatgggaatg gcattaggag caaatataac tatggttcaa tttataacta atttggtatt
    23101 tgtaacgctt ggaaatatcg ttggaggttc catagtagtt ggagggattt attatctttg
    23161 ctatgtcaaa aatagttaga taaataatac gaattaaatt gccttttaaa gcattgatat
    23221 cagtgatatt gatgcttttt ttaaattatt t
//
LOCUS       DAGQVA010000062        23116 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.062, whole genome shotgun sequence.
ACCESSION   DAGQVA010000062 DAGQVA010000000
VERSION     DAGQVA010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23116
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.062"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            164..1000
                     /locus_tag="MIV85_002696"
     CDS             164..1000
                     /locus_tag="MIV85_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2962025.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1353..2930
                     /locus_tag="MIV85_002697"
     CDS             1353..2930
                     /locus_tag="MIV85_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBY2962026.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGIANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2923..4107
                     /locus_tag="MIV85_002698"
     CDS             2923..4107
                     /locus_tag="MIV85_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBY2962027.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4125..4724
                     /locus_tag="MIV85_002699"
     CDS             4125..4724
                     /locus_tag="MIV85_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBY2962028.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4748..5218
                     /locus_tag="MIV85_002700"
     CDS             4748..5218
                     /locus_tag="MIV85_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBY2962029.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5590..6336
                     /locus_tag="MIV85_002701"
     CDS             5590..6336
                     /locus_tag="MIV85_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBY2962030.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6397..7071
                     /locus_tag="MIV85_002702"
     CDS             6397..7071
                     /locus_tag="MIV85_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBY2962031.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7440..8786
                     /locus_tag="MIV85_002703"
     CDS             7440..8786
                     /locus_tag="MIV85_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBY2962032.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLSGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8813..10213
                     /locus_tag="MIV85_002704"
     CDS             8813..10213
                     /locus_tag="MIV85_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962033.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GESGHYKNLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10423..11859
                     /locus_tag="MIV85_002705"
     CDS             10423..11859
                     /locus_tag="MIV85_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBY2962034.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            12203..13147
                     /locus_tag="MIV85_002706"
     CDS             12203..13147
                     /locus_tag="MIV85_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBY2962035.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13316..14248
                     /locus_tag="MIV85_002707"
     CDS             13316..14248
                     /locus_tag="MIV85_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBY2962036.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENTLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14353..14820
                     /locus_tag="MIV85_002708"
     CDS             14353..14820
                     /locus_tag="MIV85_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBY2962037.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15064..15918)
                     /locus_tag="MIV85_002709"
     CDS             complement(15064..15918)
                     /locus_tag="MIV85_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBY2962038.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16084..18048
                     /locus_tag="MIV85_002710"
     CDS             16084..18048
                     /locus_tag="MIV85_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2962039.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18048..18509
                     /locus_tag="MIV85_002711"
     CDS             18048..18509
                     /locus_tag="MIV85_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2962040.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18512..18832
                     /locus_tag="MIV85_002712"
     CDS             18512..18832
                     /locus_tag="MIV85_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBY2962041.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18848..19948
                     /locus_tag="MIV85_002713"
     CDS             18848..19948
                     /locus_tag="MIV85_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBY2962042.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20068..22668
                     /locus_tag="MIV85_002714"
     CDS             20068..22668
                     /locus_tag="MIV85_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBY2962043.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDENIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYHIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         9092 a         2356 c         4066 g         7602 t
ORIGIN      
        1 atatgacaaa ttaattgatg acaataaaaa atattttgtt attgtagtat tatagggtaa
       61 attgcaaaat atatacgaaa gtaaaatttt aaatattgac attaaattaa atatactata
      121 ctatgtaagt gtgatgagag aattttttta gaggggattt atagtgaata taaaaaagat
      181 atttaataac aatgtagtag taagctccct agaagatggc acagaaataa ttgtcactgg
      241 tgctggagta ggatttaaga aaaaagtagg cgatttgata gatgaaaatt tgatttctaa
      301 gaaatatttt gttcaagacg atcaaaggga caaatacaat caaatactta ataagacctc
      361 tattgaatac tttaaaattt cagaagaaat tatagaaaag gctaatgaag ttttaaatac
      421 tcaagtgaat gattcaataa tattagcctt aactagtcac atagaatttg ctgtccaaag
      481 agaaaaacaa ggtataaaat taccaaactt aatattgaat gagacaaaac aactttatag
      541 ggaagaattt gaatttggat tatgggcaat tgatgaaatt gaaaaaagga taggaataaa
      601 attgcctgaa gatgaagcag gatatattgc tattcacata atcaatggtt tggaaaattc
      661 tcaaaaagat gaaggtatta atatactaga gttttcaaaa caagttattc agataattga
      721 agaagtacat ggatttaaat tggatgtaaa ttcattaaat tatactagac ttataactca
      781 cttaaagttt tttgttcaaa ggattctccg aaaagaaact tacaatgata gtgatattga
      841 agatatgtat aagttagtga ataaaaatta caataaacct aaagtgtgta ctgaagaaat
      901 tgcagcattg gtattagaca gatttgaata taagattagt aaagaagaag aattatattt
      961 aatgattcac ataaataaaa taacaaacag tggttgttag gattgtaact gataaagcag
     1021 gcaaaaccta agtcattgag cttaactatt agattaagtt ttttgattta ggttttttta
     1081 ttagatacaa tcaaaataca gacagtgact tttaggattg taactggtta agcaggcaaa
     1141 acctaaatca ttgaatttaa ctattaggtt aagttttttg atttaggttt ttttattaga
     1201 tacaatcaaa tacagacagt gacttttagg attgtaactg gttgagcagg caaaacctaa
     1261 atcattaaac ttaattatta aattaagttt tttgatttag gtttttctat aaatttgatt
     1321 atgtttttag ataaaaatag gaggggaaaa ttatgaaaaa aaataagtta ggtttatgga
     1381 acttcttcca aatgttagga aaaacgttta tgttcccaat agcactactt agtgtttctg
     1441 ggatgatgct aggacttggg gcaggtttta cagaccctaa gatgattgaa atggttccat
     1501 ttttagggaa tgaatatgtt aacttagttt taaacttcat gttaacaata ggattatttg
     1561 catttaacaa cttgggagca ttatttgcaa tggcaattcc actaggatta ttaaaaaaag
     1621 aaaaagagtt tggtgctttt tcaggattag taggatttat agcaatgcat ataggtacaa
     1681 atttttattt aacaagagct gatttgttag taccagcaga acagatgtca actaatggtc
     1741 aagctatgat tatgggtata caaacatata atacaagtgt tttaggtggt attgtagcag
     1801 gattaattgt ttatgcaata tatgataaag ttagtaattt aaagatacca gaatcattag
     1861 gattctacag tggaccaaga ttagttccaa ttgttagttt aatagttatg agtatagttg
     1921 gattattaat acctattgtt tggccaccat ttttcaatgc attccaaagt ttaggaagat
     1981 ggatttcttc agcaggacca ttaggatatt tttcatatgc agtggcagaa agagttacaa
     2041 ttccatttgg actaaatcat cttgtaacat ctgtattccg ttttacacca ataggtggaa
     2101 ctgctgttat tgatggagaa acgtactttg gtacattgaa catgtttatg gcatatgtag
     2161 aaaataatca gattatacct cttgatttag ctggtaaaat ggaacaaggt aaattgatga
     2221 ttcaatatgg attagctggt gctgcattgg ctatctaccg tacagcaaaa ccagaaaata
     2281 gaaaggcact taaaggactt ttaatatcag gagtgttgac agttattata ggtggtataa
     2341 gtgaaccaat agagtttcta ttcttattca tatcaccagc attatttgct ttccatacat
     2401 ttatgaatgg tatagcaaac atggtacttc catacttagg cgtgttgatg ggattcacag
     2461 gagatttaat tgcatttata agttttggtg tgttaagagg aacagctaca ggatggccaa
     2521 tagcagtatt agtagcagtt ttatattttg caatatacta ttttgtattt aagtgggcaa
     2581 ttattaagtt taatataaag accccaggac gtgaggataa agaaataaaa gtatctgaag
     2641 gaaatggttc agatttcaaa aatttgtcta catataaagg acaacaaatg atatctgctt
     2701 taggtggtca atctaatata ttatcactag ataattgtgt aactagattg cgtttaaaac
     2761 tacaagatgt atcattaata aatgaggatg caattaaaga ggctggtggt atagcagttg
     2821 ttaaattaga tgagcataca atacaagtaa ttataggaac tcaagtgtat tctttaagaa
     2881 agcagatgga taaagctatg gaaggtcatt tggaggcatg taatgattaa ttttgataaa
     2941 aaagtagacc gattgggtac atattgtacc cagtgggact atgtagaaga tagatttggt
     3001 aagaaggatt tgcttccttt tacaatttca gatatggatt tagagtttcc atttgaaata
     3061 acagaggtgt tgcaggaaag gttaaatcat agagttttgg gatacagtag atggaaacat
     3121 gatgatttta gaaattcagt tacgaattgg tatattaaaa gatttaattg tagcgttgat
     3181 agtaactgga tatattatag tccaagtgta atgtattcaa ttagcaaact tattgagatg
     3241 ttaagtaatg aaggagatgg aatccttata aatactcctg catacaatgc tttttatgat
     3301 gtgataataa ataacaatcg taatattata aagtcacatc ttgtaaatag gaatggattc
     3361 tattcaattg attttaatga ttttgagaaa aagtgtaaaa aatctaagat atttatttta
     3421 tgtaatcctc acaatccaac tggtagagta tggagtgagt tagaacttgt taagatgata
     3481 ggaatttgta agaataatga tgtcaagata atatcagatg atatacacat ggatattgta
     3541 tatgacaata gaatgacacc tatcttaaat gttgcaaagg actatttaga ttctgtattc
     3601 atttgtacat cagcgtctaa atctttcaat ataccagcat tgactgggtc atatgtgatt
     3661 ataccaaatg aaggtattag aaataaattt gaaaatatca ctagataccg tgattttgta
     3721 aattcgccag caattctagc aatattagct acaatggtct gttatgatga ctgcgaatat
     3781 tggttagatg aactattaaa ataccttaaa gagaatctta aatatacgat tgattatata
     3841 aaagataatt tagaaccatt gaaattggtc atgccagaag gctgttactt tgcttggata
     3901 gatttttccg aacttaaaat aagtggtgag aaattccaaa aattattgat ggatattgga
     3961 gaagttgcta ttatgtcggg gtctgtatat ggtgaagaag gtgagtttta tttaaggtta
     4021 aatgtggcat gttcaagaga aaaacttgaa gatggtttaa ataggattaa aaaaactatg
     4081 gattatattg caaaaagaat tttatagtag gaagggagat agttatggga tatttaaaaa
     4141 caatggttga tgttatgact actgaaatga atgccataag atgtttaata gatgaagcag
     4201 gaatagaata tgaaagtata gttagtgaaa ttgcaaattg tgaaggcaaa gtaattttta
     4261 tgggtgtagg aaaatctgca catataggta agaaattggc agctacattt gctagtactg
     4321 gtacacctag cttttttgta catgcaacag aggcagtgca tggagattta ggaatgattg
     4381 aaagtaagga tattacaatt ttaatatcaa atagtggaaa ttctatggaa gtggtaaact
     4441 gtataaaata tattaaagca ataggttcta agacaattgc atttacttca aacagaaatt
     4501 cagtactggc aaaagagtgt gattatgctt taatatatcc tgcaaaggat gaagcagacc
     4561 atttaaatct agcaccaaca acatcatcta caattacttt ggttttagga gattctattg
     4621 catgtgcatt atctaagagt agtaattttg gttcttcaga tttttataag taccatccag
     4681 gaggaagttt aggtgagaag ttaaaaacag ctaacaatgg ataaaagcaa aaaggagagt
     4741 agtttttatg ttcaaaatgt ttaaaaaaaa atcaataaaa tcacccatat caggaaaagt
     4801 aatagagtta tctaaaatac aagatggtgt attttctcaa aaaattatgg gagagggtgt
     4861 agctatagat tctacaggag acattgtata tgctccaatc aatggaaaga tagtagtagt
     4921 agcagagact aaacatgcat ttgtaataga attagaaaat gggatggaac ttcttattca
     4981 tgttggttta gatactgtaa atttaaaagg cgaaggtttt gaggtattgg tgagtatggg
     5041 agaacaagtg aaggaaggaa caccaatgtt gaaaattaac cgtcctttga ttgaatcaaa
     5101 gggtatatca cttattactc cagttacaat aactaatcat tcagagtaca atatgaatac
     5161 atgtaatgta ggcaatagtg ttgaaggtgg gaaagatact gtaattgagt ttaaataaag
     5221 aactaaaata caaggttaat atttataaat acctataaac ttatgtttta taagattgat
     5281 tgtatagatt tgttgtatag atttgttgta taaaaaagaa ctctttaatt ataaattaag
     5341 gagttctttt ttattttgta aatattgttt agatttatat agaaaaacac ttagtaataa
     5401 atagaataaa taagtattta tatagctaaa aatctaaata gttttgttta aatatatttt
     5461 tatattttgt aatttcaaat taataaataa ttagatttaa taaacaaaaa ataaaaatgt
     5521 tgattatatt aataaacttt aatataatat atttatgaaa aatgtaaact gtgaaatgga
     5581 ggtagtaaca tgaaaattga aaatctttct attgatgata ttaaacgagg ctatatattt
     5641 aatgatgatt taaattgtta tagttgcatt aaatgtacaa aaacatatga ggtaggagaa
     5701 atatataaaa taggtaatag attctttgaa gcttcaaaag ctattgaact tcatatggaa
     5761 ttagaacata gtgattattt agagcaattg cttaatagtg attcaaaata caacacattg
     5821 actgaaaatc aaaaacaatt atttcaatta tttattagtg atttaccaga taaggagata
     5881 gcaaaacagg ttggagtatc cacatctact atacgccatc aaaaatttat tttcagagaa
     5941 aaagcaaaac aggctaagct ctatttagca ctatatgaat ctgtatttga agataaatct
     6001 aataaaagta gtactataat accaatccat gaacatgctc gaatggtaga tgaaagatat
     6061 gtagtaactg aagaagagag aaaacacatt ttggatacat catttgaaag tatgaatcct
     6121 ttaaaattaa aagtattttc ttcaaaagaa aagaaaaagg tcgtaatttt atctaagatt
     6181 ttggaacaat ttgaacgtgg gaagaaatat tcagaaaagg aagttaatca gattttagaa
     6241 tctatatatg atgattttgc aacaattaga agatatctaa ttgagtatgg ttttatgagt
     6301 agaaataaag aatgtacaaa atattggtta acataattaa aataataaat tttactaatg
     6361 tgtaatgtta tttttatcta gggggaggag tcaaatatga atgatgaatt aaaatctatt
     6421 ttatacaata aaggtgtaga cattgttcgc tttgttgata tatctgaatt tccaataaat
     6481 caaacacaag gtttttctaa agcaatttta ttttgtatag ggttatcaaa aaaatttatt
     6541 acagatatat acaataactt acctacagat agtgatgagt ttttggaaaa agaggagaaa
     6601 gtagaagaat tagctgactg gatttcaaaa tatattcaaa ataaaggata tagagcatat
     6661 tctcaatcgg agaaaaacaa tctagaacat ggatattttg aaaaagccta tattaatcca
     6721 gaaatgcaat cagggattag tcctttacca cataagacaa tagcaaatat tagtggcatt
     6781 ggatttatgg gaaaaaataa tttgtttgta acagaggaat atggatgtgc ttttagcatg
     6841 tgtacagtac ttacagatgc tccaatttct gttgaaagat atcctttgat tgattcaaaa
     6901 tgtatggatt gcaatgtttg tgtagagaac tgtcctgcaa aagctataca tggaaatgaa
     6961 tggactttac ctggaaaaag agaatctatt attgatgttt caaagtgttt ttgtgtattg
     7021 aggtgtatga tgagttgccc atggtcatta agatatgcaa atcaaaaata actttactag
     7081 agaaggtatt aaattgaata ttataaaatt tttaaaatgt aagattatat aagatttctc
     7141 aaaataaaaa tttgtataga acactcagaa atgagtgttt ttttattggg attaaattat
     7201 attgatacaa agcttaacta ttttaatcat tatataaaat ttgtattaaa aaattaagaa
     7261 taacttggta atagtgaaaa tataatgaga ttataattga tttataatat aactataatg
     7321 atattgtaaa aatgaaaatt gtcctctcaa aattcccaaa gagagtaaaa gtcacttcag
     7381 ttatagtcaa aaaaattttt ctgtgaaaag aatttagatt tgaaaaggag gaattaatca
     7441 tggaaattga aactaaaact ccagattgga ttaatgtact agaattaaac agtaaaatag
     7501 atattactgg gaaatatgat gtaagtaata tgatacaaaa tattgtctct gataagtcac
     7561 tagaaggttc cattatatat tttccaaaag gtaattactt atttgagaaa ggtattaaaa
     7621 ttagtcaaca aataacactt caaggagatt cttattatgg aggaggtaat caagtatcaa
     7681 atttagataa aaaacaatca atcataggaa caaccaattt tataacccga ggagtttcta
     7741 atatgagtat tattacattg tcaggaacaa gtcaatgtat caaaaatatt aatttttatt
     7801 atgatagtca tgatatagag aaaataccgc ctaaaaatgt atctgctatt acagaatatg
     7861 gagaaacaca aggactatct cattttgaac atctgtttat ttctggattt tcagggatag
     7921 gaattgaaat tccatactat tcaactggta atgatattac tgttagttca tgtggtcttg
     7981 gtatgaggct tggagagaag tcaatgcttt ctagtagcaa gatttacgaa tgtaaaaatg
     8041 gaatggagat tactactggt gttagcttaa ataatgtgag aatagaagaa ataaaagaaa
     8101 taggtattaa taataaagga tttggtttta acctgattat gaatcttatg gtcgaccaat
     8161 gtggatattg tggatttatg tttgaaaaaa tgtgctatag ccagataact gccagaatta
     8221 ctagatgcgg tcagtattat aaaagtgttg attataatgc ttatgagaat atggaagata
     8281 ggaaagaaga agcttattcc attttttatg gagatatttt agaaaattgc aatattgtat
     8341 tgatgaatag taatattgat accttggaaa atgattcact tgatgaacat aagatatatg
     8401 taatcaaggc aaatgaaaca aacaatgtaa tgctaacatg ttatgctgaa gcagataact
     8461 ttatacaatg tgcaaagggc aacttgctgt tagaaaatgg tgaaaatact tataaatttt
     8521 ataatggtga gatttgttct gtaggaggtg ttcaaatttc tgatatagat gaaaaagatt
     8581 taatcaaaat aatagagaac actttgtata tagatgataa aggtaagtat ttaatggttc
     8641 ctagattaaa aaagaatact gtaatatatt cagtactaga ttctacagaa gaaataaata
     8701 aattacatgg tggaatatgg gaacagattg atgtaaaagt attagctggg gaatccatgt
     8761 actattataa aaagataaaa gattaaatta tcaaactagg aggtagtgat taatggaaga
     8821 gtctataata attaaagata taagtggctg gattaatgtc cttgattatg gaatttgtaa
     8881 tgatgaaaca aaagatgtaa gttttaagtt gcaagagatt atggatgctg taccagaaga
     8941 ttctattata tattttccaa aaggaaaata cttatttgaa agtggtgtta agattaagaa
     9001 acgattaact ttatgtggag attcttatat tttggcgaat gttcctaaaa atactgctgg
     9061 agtaacacaa tttactttta aaggaaagaa aaatcctaaa agtgaaaata tagcaattat
     9121 aacagcaaaa agtgtaagac actgtattaa gagcatttgc ttttattcag atagttgtga
     9181 tagagatatg acatctaatc atgaacctcc aacagatgga aaacctagat ttcatcataa
     9241 tgtaattata aattatagaa atatatcggc tattgtatgt gaagataaac agggagaatc
     9301 aggtcattat aaaaatctat cttttagtgg tttttctgga attgcacttg atatgcctaa
     9361 taattctaca gcaaatgata ttacaatttt tacatccgga cttggaatta gtacaggaga
     9421 aaattcaact attgctaaca gtaaggtttg gggctgtgtt gatggaatga taatttctac
     9481 tggaactttt ataaatggta tgagggtaga agaaataaaa aaagttggaa ttaaaaatat
     9541 tggtagaggt ttaaatttta ttacaaatat cacaattgac caatgtggat attgtggagt
     9601 ttggtttgat tctatatcca atgttcagat atcaggaaat atcacaaggt gtgggcagta
     9661 ctattatgat gtaagctatg ataattattt aatgttggat aatagagtta aagaagcata
     9721 ttctttattc tatggtaatt tattggaatc aagtaatata gttttatcaa ataccaataa
     9781 agataattgg gaagatttca aagaagataa gcataaggtg tatcttgtag aagcacttga
     9841 aaccaagaat gtactattaa catgcaatat agatgctact gactggattg ttaagtcaga
     9901 aaaaggaaat ttaacgtaca ataatatgcg acaaactgtt atattttacg atggaaaact
     9961 aagtagtatc aatggaattg gtatatctga tgaagattat ggggataaag tcaagataaa
    10021 aaaaggaaat atatatataa atagtaagga taaggatatt aagatgcata aaccagaggt
    10081 aggtgacatt atgtcaacaa ttattaaaga taaaagtatt ctttctgctc attatggggg
    10141 aacatgggag aaaattggtg aaaaaataga gtttggaata actgtacact attataaatt
    10201 gatagagaaa taagtaaata cgtagtattt gaatagatgt attttattgg agagctagga
    10261 ctatagtttt aatgtaaatg gtttggtaat agcatggatt gaataatata aaaataatat
    10321 aaaaaattaa tttgattatg taaaattcta tgaagtagta aaactgtgac tttagtcata
    10381 ggaggttcaa actaagtaaa agggaaagga atatataata ttatggaagg aagaactggg
    10441 attaaagatg gaagatggat taatgtagta gaaagaggta ttaaaaatga tggttcgtac
    10501 aacgtaggtc ctgctttgca ggatattatt gatgaaatag aaacagattt ttgtgtctta
    10561 tattttccaa aaggtaaata cctatttaca agtggtgtta aaattaataa agaaattgta
    10621 ttgcaaggtg attctaattc atctacaggc actacacaat ttataactcg tggagtagaa
    10681 aatatgagta ttattacatt gacagggaaa aaacaatgta ttaaaaatat aaatttttat
    10741 tctgatagtt gtgagataca ggtaaataaa gaaccaccga caaaaggtaa tcctaaatat
    10801 cattatgaga tgattattaa taagaatgaa aagaatgttg agatgaataa tgtatcagca
    10861 atcctgtatg ataacagtaa gaatatgatt aaaggtctag gtcattatga aaatatttat
    10921 ataagtggtt tttcgggtac aggaattagg ataccatatt actcaattgt aaatgatatt
    10981 acagtttcat cttgtgggct gggtattgat acaggaatag acacaattat ttctaatagt
    11041 agaatatcta agtgtcaaaa tggaatgagg attagaactg gaactagtat aaataatgta
    11101 aggattgaaa aaatacagaa agttggtctt ataagtagtc aagttaaggg gtatgagggg
    11161 tatggaagtt ataaaattaa taatattacg attgaccaat gtgggtattg tggcttttca
    11221 tttgattcaa tgaaagatag ttatttttct ggtattataa gaaggtgtgg tcagtattat
    11281 tataatacag attatgacac atatttaagt attaaagata gagtagaaga agcatattct
    11341 ttattttatg gaaattattt tacagaatgt aatattgatt tagttagtga taataaggat
    11401 aactgggatg atggcttaga atataaacat aaagtttatg tatttaaaac ccttcaaata
    11461 ccaaaattaa cattgagatg caatatagat gcctatgatt atatcgttaa atcggtacat
    11521 ggaggaggta atttaatgtt aaaaaataat tttaacaatt atatatttat tgattcatct
    11581 aatccagaag ttattaatgg aattaatttt aattatcaaa agaatggaaa cttgttaagg
    11641 ttaaataatg gtaaattaag ttataaaaat ggaaaggaag aaacagctat attcagacct
    11701 aattatggtc ttattgtagc atcaacagat tcagaatgtg aacaaataga gactagctat
    11761 ggaggaaaat gggagaagct tggttctgaa gtaattggag aagaaacggt atattattat
    11821 aaacatcatg aaccagataa aacaaaccaa atacaataaa atttgtatta tataatgata
    11881 taaagtttta atatatagtg tttaccttta atgtaatatt ggtatatttg tatagtatta
    11941 aatttgttaa aaagtaaaat tgtagggtgc ttgaaaatag cacctttttt agtttcatta
    12001 taaaattagt tttgaaagtt taggaataat gtatatttat ttttaaagaa ttataacctt
    12061 attaaggata ttttaaatgc tagaaatgaa tcagtaaatc atactggaat tatcttaaat
    12121 gttttgatta aattaagtat ttagagctat aattatatta aaaatatatt agaacataat
    12181 tatattacta tggaggttaa atatgatagt aagtgtgagt agaagaactg atatacctgc
    12241 tttctatagt aagtggtttt ttaacagact taaagaaggt tttgtttatg taattaatcc
    12301 aatgaatcca aaacaggtta gtaagataga gttaaatcca catactgttg attgttttgt
    12361 attttggaca aaggatgtaa ctccaatgtt atatgattta aataaattaa aagactataa
    12421 atattatttt cactatacta taacatcata tggaaaagaa gtagagacat gtattttaga
    12481 taaaagaaag gtaatagatt catttaagga attgtctaga aaaataggca aagaaagagt
    12541 aattttaaga tacgacccga ttttcttaag tgaaaagtac acagtagatt atcatatcaa
    12601 agcatttgcg agtttatgta atcagcttga tggatttaca gaaaaatgta taataagttt
    12661 tatcgattta tataagaaaa caaaatttaa tactaaagca ttacatataa agccaataga
    12721 aattacagaa atagaaacat tatcaaaaga gatttctaag attgctcata agcatgggat
    12781 aacacttgaa atgtgttctg aagaatataa tttaagtaaa tttgggattg gaaaaagtaa
    12841 gtgtattgat gatagattaa tatcaaaaat tataggatgt gaagtagagg taaaaaaaga
    12901 tagtacacaa agagatattt gtggatgtgt taaaagtgtc gatataggac aatacaatac
    12961 ttgcagacat tattgtctgt attgttatgc taactttaat tatgcaaaag tagaagaaaa
    13021 ctgtaggctt tataaagaag ataataaatt actcatagat actttaagag atgatgcaaa
    13081 aataagcatt agagatatga agactattaa agtagataag aataaacaaa ttagtatatt
    13141 tgattaaaat aaatatacta attaccttaa tatattaaga atatagatac ttttgataac
    13201 aaaattaaac ttaatagata ttttctatat aagaaagatg gtcataatat gtcaatttga
    13261 ccatcttttt gatataatta aaacacaaat aatttagtaa caaaggaggc agaacttgaa
    13321 tttattaaaa aaatatccta tacctattgc aagtttgatt ttgtcaatct ttactttagg
    13381 taacttatta caatcttata gtgaatcatt acgtaatgta attggattta taggatttat
    13441 tttgtatgca atttatatag tcaaaataat attacttaga aagggtgtta aagagcaatt
    13501 agagaacact ttaatatcaa gtacatttcc aactataaca atggcaacaa tgatatttgc
    13561 tacatatata aaaccattat ctttagaatt aagtattatg atttggagca taggaattgt
    13621 gggtcatctt gtgttaatag tcttatttag taagaagttc ttagttaaat tctcaataaa
    13681 aacggtattt ccatcttggt atatagtata tgttgggata gttgcagcta gtgttacggc
    13741 accagcattt aatcaacttt tgattggcaa aattgctttt tggataggat ttgtatctta
    13801 tatagttctt ataccagtaa ttttaaagag agtatggata atcaaggaaa tgcctgaacc
    13861 atctttacca agtatagcta tattagctgc accagggtca ctattattgt ctggatatat
    13921 taattctttt tcagataaaa ataatgtagt attatacttg ttattcatat tatcaattgt
    13981 attttatatt atagttttgg gatatttacc gaaattatta agattgcctt tttatccgag
    14041 ttttgctgca tttacatttc ctatggcaat aagtgcaatg ggtatgaaac taatgaatgg
    14101 ttatttaact aaatcaggtc attttataag ttggatttca tatgcttcta agttagaaga
    14161 gataattgct acagtgatta ttttatatgt tttagttttg tttattatat atcttagtaa
    14221 atctgaaact acatctaaag ctaaataaga attattaaat atgtgtattt aataggaata
    14281 ttgatataaa tatatgaaga taagataaac catagaaact taatttagct taattttatt
    14341 ggaggaaaac aaatgaaaac aaaagaagaa tatttaaaag aagttagaaa catatcagaa
    14401 gaatacttta gaaaaggaga gtttttttgc tctgaagcag ttctccagac aataaatgat
    14461 gctttaggcc aacctttaag tccagagata actaagttag catcaggatt tccgatagga
    14521 cttggaaagg cacaatgtct ttgtggagca atatctgggg gagagatggc tttaggtata
    14581 gtatatggaa gagttcatgg tgaagctatg aatccaaaga tgtttgagca tgctaaaggt
    14641 ttgcatgatt atattaaaaa agagtatggt gcaacatgtt gtagagctat tacaaagaaa
    14701 tgggatggtg ataactttat gtctcccgaa agaaaagagc actgtattaa aataacaggt
    14761 caagttacag agtgggttgc agataagctt atagaagatg aaaaacttaa tatcaaatag
    14821 tgtaatatta gttggtgaat ttataaagtt aaatttactt atagtataag atacttgata
    14881 ttctcgtatt gatagaaaaa tttatagcat atgtatttaa tgaaatatac ttatatttag
    14941 agtgtggttt aatttcataa atacatatgc tattatttta agtatataag caaatttatt
    15001 taaataaata gaaacagtta atttatatgt acaaaactat atatgattag tgtaaataaa
    15061 tacctatttt ataatactca acataaagac accagacatg attagtatta taccaataaa
    15121 aatagcaagc cattcttttt tgttcttctt ttctttaaaa aatataatcc ctcctaaagt
    15181 ggctactatc acacaactct gagagataga aaaacttatt gtaactccca atgtattagt
    15241 cgttatgaac atacctaaat ttgctattga ccacaatata ccagtaatta aattgaataa
    15301 aacattttcc ctatatacaa tctctttaga aaaatacttg acaataatag atgaagttat
    15361 caacatacca acagattgag gtaatataat tctatatcct tcaattaaaa atatttgatt
    15421 agttacaaca tataatgata aaaatagaga tgataataat acaactccaa cacattttaa
    15481 catattttta tctgtagatt ttttagtttg ataatttgtg agaagtatac caagtattat
    15541 acataatatt gataaagaac caatcagtaa cattttagaa ctggtccatt cattaaacaa
    15601 gattacagct aataatgtcg taaaagttaa ttgtgaacca tttgaaattg gcattacttt
    15661 agatacacta gcaatttgaa ttgctttaaa ctgcattaat tgtcccaaac tccagaatat
    15721 gccagaaatc atacttatac aaaatgaaaa aaatgtaatt tcaggatgta taaccagagt
    15781 tattatagtg gaaaatataa acgcacttat ggatgtacct aaaagctgtt catgaggaga
    15841 acttttcttt agatttgcaa ctatgggcat caatccccat cccattacag gaagtaaagc
    15901 aataattatt gtcagcatta aactatttcc tttcatatta aatttagaca gcttttaatt
    15961 tatcatctaa aattaaagtg ttcaatacat aaaaattacc gtatttaatc aggaaatatt
    16021 agtagttttt tagaaaaaca ttttccatta aaataaagac aaagggaagg agtaaaattg
    16081 aaaatgttaa ctgatatgat tcaaaatcgt gaaattaaaa taataaagtt tttattaaaa
    16141 gaaggtcata caactgtaaa agcaatagca gatgatttag atgtttcaga aaaaacagtt
    16201 tcaaaatctc ttaaagaagt agaagcagtg cttaaaaaga taggtctttc tttaataaga
    16261 aaacctaaga taggtgttta tattgatgga gatttaaaaa aaatacttcc ttacctagat
    16321 aataaaggaa gtcaaattcc tacaaccaga gaggagagag ttatctatat atattcagta
    16381 cttttaaaga gtaatgatta tattactata caacaacttt ctgatgaact atatataagt
    16441 cgtggaacta ttgaaaggga tttagcagaa gttgaaaaac tgctaaaaaa cgaagggatt
    16501 tccatatata agaaacctag taagggaata aagttaaata taagtgaaag agataaaaga
    16561 caacttactg ctaagtttat acataaattt tggagtagaa actggtatat taagcaagag
    16621 caagaaagct tttatcaagc atttgaaaag atacaagcag atgtaaatgg tattttttcg
    16681 gaagatgatt tatcaataat tattgatatt cttaggaatt tcagcagaga aagaaaattt
    16741 gagttctctg attatgaatt tcagtcatta gttattcatt tggcaatagc tgtagagaga
    16801 attagaaaag gcgaatatat agaagaaagt ttgtatactg gtaatataga aaataatcaa
    16861 atgtcaaata ccaattattt agcaaaacaa ttagaagaaa aattttcaat attattacca
    16921 aaatctgaaa ttggatatat aaatttacat ttagtagcgt ctgaccaaca tagagatact
    16981 aatgaactaa aaaatacttc aactaatcct tgtgagacaa gtacaaataa tatatcaaat
    17041 cttcgggaaa ttataaaaaa tacattgtat gagacagctt atgacaagga tttaattgat
    17101 ggattgactt cacatgtaca ttcatcaata aatagactga aatatggact tagtattaaa
    17161 aatccatatg taaatacaat caaacaaaac ttttctttat catttgagca agctttagat
    17221 ttaaagaaag taattgaatt tatatatgat attaggataa atgatgatga atgtgcttat
    17281 atagcattac attttgaagc ttttagagaa agaatgaaag aacttccaca aaatattaga
    17341 gtaattctag tatgcagtac aggattaggt tcatctaggt tattgtctgc aagaataaaa
    17401 aaatactttc caatgataaa gattgaaaaa gtactttccg tacaagaatt agtatccagt
    17461 aaaattgatg cagatttagt aataagtact atttatttag agttagaaac aattccaacc
    17521 atagtagtta gtcctatttt aaatgaaagt gatataagaa ccttggaaag aaatatacaa
    17581 aatgtttcaa gttgtacttc taagaagtat aaatctttca gaaacttaat ctttgaagaa
    17641 aatatattgt tgaatattga agcttcaaac tatgaagatg caattaagta tataacagat
    17701 aacctaataa aaaaaggttt tgcaaaagaa ggtatagcta aaagtgcaat tgagagagaa
    17761 aatttatctt acacttcttt ccaatcaata gctacacctc atgctaatcc tagttatatt
    17821 aaaaaatcta atatatctgt tgcaacgtta aaaaatccta ttacatgggg aaatgaaaag
    17881 gtggaagtta ttttctttat ttcattagaa aatgacaaaa acctagagct tgatgaaata
    17941 tatgaagttt tttatgactt tattgacaat aaaaaaaata taaatgacat attaagtgca
    18001 acttccacaa aggaagtgta cgatttgcta gtggaggaga gtatatagtg aaaatatcag
    18061 atgtattgaa aaaagagcaa attgttttta atcttgatac aaatacaaag gaagaaacaa
    18121 taaaaaaatt aagtagtata tttgttgaaa atgggattgt ggacaatgaa gaagaatatg
    18181 ttaagtctgt tttggaaaga gaagaacatt caactacagg tattggtaat ggtattgcta
    18241 ttcctcatgg gaaaagtaat gctgtcaaaa aatcttctat aatatttgca aagactaagc
    18301 ataagattga atgggatgct ttagatgaaa aaccagtaga tagtattttc ttattggcta
    18361 taagcaatat tgataaggat agcaatcatc ttgtactatt atctaaatta gcaactaaac
    18421 ttatggatga tgacaatgta gatgcactaa aattagccaa ttcagaacaa gaaataatca
    18481 atatatttag tgaagaagga gagatgtaga aatgaaaaga aaaattatag cagttacagc
    18541 atgtgcaaca ggagttgcac atacatatat ggcagctcaa gcattaaaga aagcttcaaa
    18601 aaagatgggt caccttataa aagttgaaac acaaggagct acaggaatcg ataatgagtt
    18661 aactacaaag gatgcacaaa ttgcagaagt agtaatattt gcagtagata ctaaagtcag
    18721 aaatgctgaa cgttttgagg gaaaagaaat actagaagta ccagttaatg cacctataaa
    18781 ggatgcagag aaagtaataa atgatgcatt aaagttaatt gacactaaat aaatggaggg
    18841 aaatgtaatg ttgaaaaaga tagtctctga gttaaaaaag catgtcttaa ctggaatctc
    18901 atatatgatt ccattagtaa ttgcaggtgc tatgataatg gcgatatctc gtgtaggtgg
    18961 ttctttctat aatataccag atatatggga tgctaaatat gcagaaagtg ctagtagtat
    19021 tgttagatta ttacatgatt tagatgggtt tggaggtact gcattaggat taatgtttcc
    19081 tgtaattgct gcatttatag gattttctat agctgataaa ttagctattg taccaggtct
    19141 tgttggaggt atgattgcta aagatatagg tgcaggattt ttaggagctt tggcagttgg
    19201 tcttatagca ggatatacat gtttgtttat taaaaatcat gttaaattac caaaatcagc
    19261 agcttcaata gtaccaatat ttatagtacc agtatttggg acattaatca ctgttgtatt
    19321 aatcaattat gtgataggta taccttttgc cacattaaat actggattag aaaattggtt
    19381 aaatggatta tctggtacaa atcagatact aatggcagct attatagggg ctatgatggc
    19441 agttgactta ggtggaccag ttaataaagc agctttaaca acatcacttg cattattaac
    19501 aagtggaatt tatgcgccta acactgctgc aatggtagga atagttatac caccactagg
    19561 attgggactt gctactatac tagcaaaaca aaaatataat aaacagttac gtgaagctgg
    19621 aaaatcatct cttataatgg gtttaattgg agtaagtgaa ggagcaattc cttttgcggt
    19681 agaatctcca ttaaaagtaa taccttcatg tgtaattgga acagcaattg cttcagctat
    19741 ggcagttggt ttaggttcag taaatgcaac tccaattagt ggattttatg gatggtttac
    19801 agtagagaat tggccaatgt atgtgttatc aatagcagtt ggaacagtaa ttgtagctgg
    19861 attagttata gtattgcgtg gaaatccagt gattgaggat gatgaatttg aagatgatga
    19921 ttttgatgaa gcagagtggg aatcttaaaa tttaataact atttaagacg tgttataagc
    19981 tatattcaat atgaatctta tactaaataa agtgttaaat attcagttta gacttaaata
    20041 taaaagataa agaacagagg agaataaatg ataaaagcac atattgttaa tcatacacac
    20101 tgggatagag aatggtattt tacttctgga gatgcattag tacttagtga acaactattt
    20161 acagatgtaa ttgatgaatt agaacgtaat ccagatgtaa gttttgtact tgatggacaa
    20221 ctttctattt tggatgatta tgtacaatta cacaaagaaa aaatagaaat cattaaaaag
    20281 ttaataaaag aagatagact acatattgga ccatggttta ctcaaactga tgcattcttt
    20341 gctagaggag agtctatttt aagaaactta atgattggaa tttttgaaag taaaaagtat
    20401 ggtaagtata tgaaaattgg gtatttgcca gatacatttg gatttaatgc acagatgcct
    20461 atactattaa agcatgtagg tcttgataat atattctttt ggagaggtat acatcttggt
    20521 aaacaggttc aatcaccata ttttaagtgg aaaagcttaa atggagaaag ttatatatat
    20581 gcagtaaata tgccacatgg atatggaact ggtatgcttt tagagccttc attaaagtat
    20641 gttaatggac gcttagaccc agctattgat tttattaaat catatactga tgtagatgag
    20701 gtgttaatac cttctgggaa tgaccagtta aatataatag gtgatttcaa aaataaaatt
    20761 aaagcgatta atgatatcgg aaagtattca tatataacga gttcatatca agagttttta
    20821 aaatatataa agtccataga atcactagaa agctatagag gtgaatttag agaacctgta
    20881 ttagcaagaa tacataaatc aattggttct agtagaatgg atataaaatt agcatgtgat
    20941 aaactagaaa acaagctgat taaaagaata gagccattat tagtaattgc taaaaagagc
    21001 aaaattgaaa taagcaatca gttacttata aatacatgga aaaaactttt ggaaggacaa
    21061 gcacacgata gtttagctgg atgtgtaact gatactgtaa cagatgatat tcttcaccgt
    21121 ataagagaag caaatgaaat atgtgacagt attgaaaata ctattgtaaa aaagatttca
    21181 gaagggctta aattatctaa aaatgatatt ttagtattta atacagaagc taagcgtttt
    21241 aatggatata aagagataca agttgtaagt gatagtaaaa atatttattt taaagataat
    21301 ttagatgcta ctataattga agaaacttat gtaaaaccga gagaaaatgt attagaagaa
    21361 acacctgctg gtaatatatt tattgaagaa ccaggatatt atatattaaa agtaagaata
    21421 aatgtacagc ttcctgcact tggttataaa gttgttagtt ttgaattaag tgataaagaa
    21481 atggtgtcac ttgataaatc taatgacact tttatatcta atgataatta taagataata
    21541 tatgaagatg gaagcttaaa tttacaactt aaagatggaa cttacatatc aaacttttta
    21601 acattaaaag atagtggtaa tgcaggtgat acctatgact tttctccact aaaaaatgat
    21661 gagaatataa aactttcgtt tgataaagtg tatacagaaa aagctttagg atatgaaaaa
    21721 atggtggtta aaggtactac tttactacca cttacattag aagatagaaa aaacaaatat
    21781 cttaatggta aattaaatgt aaaagtaagt attgtcttat ctaaagaaaa cccattgatg
    21841 gatgtaaaac tttgtgttga taacacgata tataatcata gactacgtgt tcatataaaa
    21901 actgatataa aagataataa aaacatagca tcattgccat ttggatatat aacaagaaaa
    21961 aatggagttt tagacaactg ggaagatatt tacagtgaaa tgcctataga tttagaacct
    22021 ttggaaagta atattacgct tacaaaccaa aatagaagtt gtactgtatt tactagagga
    22081 ataaaagagt atcaacatat tgaagatgaa attgcattga ccttacttgc tactacagat
    22141 gaactaggaa agcctgattt attatataga ccaggacgtg cttctggtga tacaactaaa
    22201 aaaggtcata taagaattaa aacagataaa gctcaaatgc ttaaggaatt agaattttca
    22261 tttgcaatat atatggattc taaatcattt gatgaattgg aaattgcgaa tttaacccac
    22321 aattatctaa gggaatgtgt aaattatcaa ttacaggatt acaatttctt tttatatcat
    22381 atagataata agattcaaaa atcaattgtc aataaaactg taagtagaga attagaaata
    22441 atatctttac cagaaaacta tcttatatca gcatgttatc cttcttatta cagtaaagat
    22501 aaatttataa taagagtgga aaatccaagt agtaatagaa tgatattgga tgagcaaata
    22561 tttaaaaata gaaatgggaa aattgtaaat gcaatagaag atgtagaaga ggaacaggta
    22621 tatgaaatag caccttttga cgttatttca atattattgg atttataagt gtaaaagtaa
    22681 gtttattgtt taaagtctga cagatattaa tctgccagac tttttaattt gtataaattt
    22741 gggtaaatat taatgaatgg ttttagtatt taagtatgaa tttagtattt aatatagaat
    22801 ttattgaagt agaataatta gtttaacagg ataagcagtt taaataaaga attattatat
    22861 tagagtgatt ttatatataa tttaaaataa taaaatttta ataaaatgag ttaaagattg
    22921 tatattaata gagttgatgt agttacaaaa aagttaccaa ttgttatgta tttacaaaac
    22981 tgatatatta attacataaa atctaaaata gtttgtaata ggagtatata taataaaaat
    23041 tttaattaaa taaagctagg tatatttata atattaataa atatattgct ataaaagttt
    23101 gtttaataaa ttaaat
//
LOCUS       DAGQVA010000063        22459 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.063, whole genome shotgun sequence.
ACCESSION   DAGQVA010000063 DAGQVA010000000
VERSION     DAGQVA010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22459
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.063"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            41..922
                     /locus_tag="MIV85_002715"
     CDS             41..922
                     /locus_tag="MIV85_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBY2962044.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSIKDVEKFINFFSAIPAKDTDDTIKISEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(1235..2014)
                     /gene="hisJ"
                     /locus_tag="MIV85_002716"
     CDS             complement(1235..2014)
                     /gene="hisJ"
                     /locus_tag="MIV85_002716"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBY2962045.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLILGSDSHCAEEINKYDIV"
     gene            complement(2560..2910)
                     /locus_tag="MIV85_002717"
     CDS             complement(2560..2910)
                     /locus_tag="MIV85_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBY2962046.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(2926..3342)
                     /locus_tag="MIV85_002718"
     CDS             complement(2926..3342)
                     /locus_tag="MIV85_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBY2962047.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(3361..3552)
                     /locus_tag="MIV85_002719"
     CDS             complement(3361..3552)
                     /locus_tag="MIV85_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBY2962048.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(3703..4518)
                     /locus_tag="MIV85_002720"
     CDS             complement(3703..4518)
                     /locus_tag="MIV85_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBY2962049.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(4565..5503)
                     /locus_tag="MIV85_002721"
     CDS             complement(4565..5503)
                     /locus_tag="MIV85_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962050.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(5500..6372)
                     /locus_tag="MIV85_002722"
     CDS             complement(5500..6372)
                     /locus_tag="MIV85_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962051.1"
                     /translation="MNKNLSEKMEIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(6397..8325)
                     /locus_tag="MIV85_002723"
     CDS             complement(6397..8325)
                     /locus_tag="MIV85_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBY2962052.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(8437..8814)
                     /gene="gcvH"
                     /locus_tag="MIV85_002724"
     CDS             complement(8437..8814)
                     /gene="gcvH"
                     /locus_tag="MIV85_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBY2962053.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(8901..11027)
                     /gene="cdhC"
                     /locus_tag="MIV85_002725"
     CDS             complement(8901..11027)
                     /gene="cdhC"
                     /locus_tag="MIV85_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBY2962054.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(11084..11890)
                     /locus_tag="MIV85_002726"
     CDS             complement(11084..11890)
                     /locus_tag="MIV85_002726"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBY2962055.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(11940..13307)
                     /locus_tag="MIV85_002727"
     CDS             complement(11940..13307)
                     /locus_tag="MIV85_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBY2962056.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(13338..14282)
                     /locus_tag="MIV85_002728"
     CDS             complement(13338..14282)
                     /locus_tag="MIV85_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBY2962057.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(14302..15072)
                     /locus_tag="MIV85_002729"
     CDS             complement(14302..15072)
                     /locus_tag="MIV85_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2962058.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(15128..16513)
                     /gene="lpdA"
                     /locus_tag="MIV85_002730"
     CDS             complement(15128..16513)
                     /gene="lpdA"
                     /locus_tag="MIV85_002730"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBY2962059.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(16557..17438)
                     /locus_tag="MIV85_002731"
     CDS             complement(16557..17438)
                     /locus_tag="MIV85_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBY2962060.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(17474..18148)
                     /locus_tag="MIV85_002732"
     CDS             complement(17474..18148)
                     /locus_tag="MIV85_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBY2962061.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(18185..19057)
                     /locus_tag="MIV85_002733"
     CDS             complement(18185..19057)
                     /locus_tag="MIV85_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBY2962062.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(19149..19781)
                     /locus_tag="MIV85_002734"
     CDS             complement(19149..19781)
                     /locus_tag="MIV85_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBY2962063.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(19886..21562)
                     /locus_tag="MIV85_002735"
     CDS             complement(19886..21562)
                     /locus_tag="MIV85_002735"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBY2962064.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(21811..>22459)
                     /locus_tag="MIV85_002736"
     CDS             complement(21811..>22459)
                     /locus_tag="MIV85_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase"
                     /protein_id="HBY2962065.1"
                     /translation="ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVD
                     DIPENFCKEYNGVRLLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAG
                     IEHLGRGTAQGVDAFIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEE
                     FIIQNLEDGESLGFIYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
BASE COUNT         6764 a         4541 c         2538 g         8616 t
ORIGIN      
        1 aaatatgtcg acacaataaa tttaaaaagg agaattaaat atgaaaaaaa gattaataat
       61 aatgatattg tctgttgtct tagtactatc aagtatactt acgatatttg catattcaaa
      121 tattaaatat aataataata aattgatata ttctaatatg atagataaaa aaactcaaaa
      181 tagtgtaaag gaaatcctaa aagaaaataa aattaatgaa aaagacatag atacatttat
      241 taaagcagtc aacaattata ataaattgca agttaaaata cttcaaaata atataaatat
      301 atctaaatct ggatattctt caatcaatgc aaaacaagtt ccatataacc tagaaaaatt
      361 gcaagataat tgggtgaaaa aattccctga ttatatggat gtaaattgta gaataactgc
      421 ttttagactt tttaaagatt ttataaattc aaataagaaa tttactggag actctattga
      481 tttgaatgtc gacttggaca ctataatgaa taataaagat gctaaattta gcatcaaaga
      541 tgtagaaaaa tttatcaact tcttttctgc aataccagct aaagatacag atgatacaat
      601 caaaatttca gaacaaataa aaaatgaatg gaaaaaaaga aaaatatctt ttaaaaataa
      661 taaaaatata tctattataa atggatttct tcgttatcca gaaactaaaa acgtatttat
      721 aggtcataca ggcatatgta ttaaaactaa aaatggcatt ctatttttag aaaaatacgg
      781 tgttacatca ccttatcaag ttactaaatt taaaaataaa gaagatgtaa aaaattatat
      841 gtttaataga ttgaagatgt cagaaggtga aattgaatta cctgacccta taataatgga
      901 aaacgataaa cttatgaaat aataacttta aacgcaaaat aatatttata attactaagt
      961 caatataata gagaaggtct atagatttgt gtaaatacaa gcttatctac aatcttatat
     1021 aagaatattt atataaataa gatagattaa ttctaagtcc tattattcta ttgaatttta
     1081 ttattatttt atttagattc tattgttatt ttacttagaa cttattatta ttttgtttaa
     1141 gttctattac tattttcaat catataaatt tacaaaagac tgtacataaa tttattttat
     1201 acaaacttat ctacagtctt ttgtgtgaat atatctaaac aatatcgtat ttatttattt
     1261 cctctgcaca gtgagaatca gaacctaaaa ttaatggaat atcgtatttt tttaccaact
     1321 ctaataagta tccatctata taaggctctt tgcagtactc ttttctattt ccagaaacat
     1381 tataatcaag ttcataacct ttttctttaa ttaactttat taactcttca agaattgtat
     1441 ttcctttata atcgtatgga aatacctgat taaactttct aactaaattt aaatgaccta
     1501 ttctttttgg tttatgtata cctaaatctg aatttacagc ttttatcaat gtttcataat
     1561 acttattata aacagcttca atacttccta atttgtcgat taaattttga aactcctcta
     1621 cactgtaatc tacacaataa taatcatcat caatcttaat tatatgtact gataaaagag
     1681 aatcctctaa ttcctttcca tatttattta aattctcctt tatcccttct tcgtatcctt
     1741 ctataaaatc cacttccgac ccaacattta tcttgatttt accctcatac ttttctttca
     1801 acttcttgac atcattaaaa tactttggta aatcttcaat actcatacaa ctatcatttt
     1861 caggagcagg gtctctaaat ccatttgcat acggaaaatg ttctgtaaat gtcatttctg
     1921 ttattccaac atccattgct ctttgtacat atttttcaaa atcatcctta cttccatgag
     1981 gacaataagg tgaatgtata tgaccatctt tcataaataa ttcactcctt ttttaaagaa
     2041 aaaatctaat ataaatgcat aaatctttta acttcaaaat aatattttta atcatgctaa
     2101 tttttattat atctaatatt agagtaattt taaactgcct tttaagtatc ttatcattag
     2161 tactattttc aacttaacat taatattatt ttttaactta acattaatac tatctttaaa
     2221 tagtaatact caatatataa ttacttaaca taaaataact caaattgctt gatgaggctt
     2281 ttgcagtatt taaagaatat ataattattt aacattaaat aatccaatct tgtaataaaa
     2341 tttactcatt aaagtatatt acagaaaata cctcaaaata aactttttag ttcatgatat
     2401 actctttttt gcatgaaatt agatatattt ttatcatttc aacaatgaaa gggaggctta
     2461 tatccatctt tagacaaccc cttagataaa atttttaata attaaacatc acaaaatata
     2521 aaaatcgctt atatcaaacg tataagcgat taattatatt tacatatgtt ttttagcctc
     2581 taacaacatt ttattagctt cttccatata ctctatagcc ttttcaatac tctttgctgt
     2641 ttcttctttt ccaatagctc tagccttttc aacccactct ctaaatcctt cttcatgagt
     2701 ttcattgtga tttatccaat gtactaaaag tatttttaaa gttttttcat ccttagactc
     2761 tgatgattcc tcatgactat gttcgtggtc gtggtcgtga gcatggtcat gtggatgttc
     2821 atgacatata tctccatgag tatgttcgtg gcagtggtca tggtcatgat gtccatgatg
     2881 atatcttaca atctctttat caaaaatcat tagttattcc ccctgttatt ttatattaaa
     2941 ctcttttttt ataaggttta cagaatcttt tacaagtagt gctaatggtt taccttctaa
     3001 tccaactaac tccacatttt ctggcataat aggtaaaagt atcttaagtg cctcactgtc
     3061 tgcaatagct tcacttatat tacaagtaac ttctcccatc atagaattag gtattattac
     3121 agaaataggt gcaactatta tatttgcttt tttagctgat actactatag cattttcccc
     3181 tgtagctcct ttattagcat gagctttcat catagaacta gttgctatag aattagtccc
     3241 tagtgcataa atttctacat atgtaggtaa ctcttctctc aaagaagaaa ctatctgggc
     3301 tccaatacct ccacccattc catctatcac tgctattatc atatgaaatt cccctattaa
     3361 ttaattttct tgtattatta tcttatggtc catcaatctt atttctttaa ttatcccatc
     3421 tattatcttt tgctctccta ataaatccgt taaataaatc tttccatcac aagggtctat
     3481 attaaccaca ttttccataa ccttttctaa ctcattatta cttttacaaa tgaaagctga
     3541 tgattcacac atataaatct cctcctaata tgatttttat taaaaatcaa aaaaagattc
     3601 ccttaggtat ttcaatacac caaagaaacc ttcatgattt cagtttttgt atattattat
     3661 accttaagta tatcacttta atttatgtaa agtcaattaa agttaacgct ttttattata
     3721 ctcttcattc ttgtattttt catatagttc tttaactaat tgcttctcat aatcagtcaa
     3781 atcgccctcc acaaactcaa cattaaattg ttcagctaat ccctttacta tgtttttctg
     3841 tagaatatct atgtctattt ttctgccaat ttcattttct attccacttg cttttttagc
     3901 tgtaaatttc atagctcttt ctttcaattc tggtgtctta gtttttatta atttaaacaa
     3961 tttttctaca tcaaaatcca gtattattga accatgttgt aataaaacac catcttttct
     4021 gctttgagca cttccaatta ccttcttatt attaatagta acttcatatg atgcatgtgc
     4081 attaaaacat gcagctgata aattttccct acttattctc tcgcctctat ttaaattatc
     4141 tgtttctata ccacttagat tcaacccttt aactagacct tcacttatat atctataaga
     4201 taggttgatg ctcttatcga ttaaaggatt atcttctcct ataattatac tataagttag
     4261 ctcattatca tgtaatacag ctcttccacc tgtaattctt ctagtatagt ctatattcat
     4321 acatctacac ttatctaaat ctatctcatc ttccaatttc tgaaaatatc ctatactcaa
     4381 acaagctggt tcccatgtat aaaatctaag agttggctta ttatgtccct tcttatatgc
     4441 agtaaatata gcttcgtcaa ttgccatatt cattgctcct tcatatgatt tattatgtat
     4501 aactctccac tgattcatga ttattacgcc cccattttta gtataaatat atcctagaaa
     4561 tcctctatag atttatttct cttattgcta aatctatctc actttgattt aaaggtcttg
     4621 aatagttgta tatagtactt cctggtcttt cattatagta tggtctatta caatccttac
     4681 aacctcttat ttcaaaagga tagcctttgt ttatgtcttt taaaatatca ttgtcaagct
     4741 ttatactatt taagtatcca tttttaaact taaaatactc ttttggataa cctttattta
     4801 tcatataaga cattaactgt acccttctat aactttctat gcttggttga tttatctttt
     4861 ccattttagt tcctctaact ggagtaaatg caaataaact aatcgttaca tcattttcct
     4921 ttaaataagt atataaattg tatatatctt catgactttc acccatacca actattatat
     4981 gtgtacttat tttattggga tatgattttg acatttcagt tataaatttt aacttttcat
     5041 catagttatt tccttttatt ttttcatata gttctttatt tgctgcatct attgctattc
     5101 ctattttatc aactcctact gaaaaaaact tctttatctg ttcatcattt tctaattttg
     5161 cagatagtga aattggcatg tctatcttac cacttatata gtttataaag tctaaaacag
     5221 agttatgtgc ttcttcactt gccattgatt gaatacatat tctctttata ttttttcctt
     5281 tataagcttt taaagcatct aatatttctt cttttgaaaa ctctggccaa attactcttg
     5341 ataatttatc ttttctagta ctactttcta ttgattgaga acaaaaactg catttattta
     5401 tgcatttttc tccaatcatt atatatgctg tggtaggagg tatatcgctt tttttgttta
     5461 atatcccaag ttctattgct gtcccaactg atagtctaat cataaaacgc aacactcctt
     5521 acactcattt attgtcatat tcatttctat agccttattc tttgcagacc ttgatggtaa
     5581 tactattcta ttgactccac acattataga taattggtct agctcttttc tatacactcc
     5641 tcttggtctc atacaaccta gattaatttc agtatctggt aaattaattc tagcttcaca
     5701 taaaatatct gctacccctt ctaactcagg aggttctaca ttttcatact cagtcccttt
     5761 tgttggaata aggactataa atgtaagctt attaggagga tttttttgta ggtattctat
     5821 aatttcatat tcacccttta tttgtcctcc ttttaaacca atacatatat gtggtgctac
     5881 ttctgtatgt tcttgtattg tattatagac ttcaatataa tcttctttac tctttttcat
     5941 cttataaact tctcttattg tctcatcatc aaacactaaa tcaaaagaaa ctatatctaa
     6001 atacttacac aactctacaa tgctatcttt atccataaga cctaaatgag cattcaatct
     6061 atatccttgc tcttttaagt ttttaatggt attaatatga gtatttatag ggacatctcc
     6121 ctcataacta caaccgccac tcaatagaaa gctagttata ttccttgatt gtactttttc
     6181 ctcatattct tctattggca ccatattgtt taagtagtga ccgttgcaat gggcacattt
     6241 caaactacat tgattgcttg tagtactaag agctagtgtc tggttaggat aagcaaactc
     6301 tattttattt ccaaaattct ttaatttaat atcaaatgct atttccattt tttcagatag
     6361 attcttattc atagtttatt ccttcttaag tacattttac tcttctagta atttctttgc
     6421 tgttgggaac tgctctatat tcgtatgtgg taagaaacat gcagaaataa attcatccat
     6481 ataacttgga tatacactaa gttcaacata agttatttga ttacctattt cttcaagttt
     6541 attttttgca tctttactta taagagctaa gtaagaacca acaagtgaac tattccctat
     6601 ataagtaaat ttttctctat caatatcagg aagtaaccct ataattattg agttttctat
     6661 gtctaggttg tttcctatac cacctgctat ataaacccta tctaatatac taaaatccat
     6721 acctaaacta tctacaagag tgtatgcgcc tgaatatata gctcctttag ctctgatgaa
     6781 attatctata tcaacttcat tgactactat atcattttct aaatcaaatt cttctttaaa
     6841 tgctaataca tactctccta tctcatgctc attaaatcta actctcttat tatctaaatc
     6901 cctgtatatt ttacctcttc tatctattac ccctttagta atcatttgac agattaaatc
     6961 aattatacca gaaccacata taccaactgg tgcacattca tcaataatct ttaatgttgg
     7021 ctctaaagtt tctttatcaa taattacttt ctctattgct cctgctgatg ctctcattcc
     7081 acagcttatc cctccacctt caaaagcagg tcctgctgaa catgcacagc tcatcatata
     7141 atctttattt ccaaatacaa tctctccatt agttcctaaa tctataaata aaacattttc
     7201 ttcacttgac catatccctg ctgataatac acctgctgtt atatctcctc ctacataact
     7261 tgcaacagat ggagctaagt acacatatgc actgtcattt acaaaaagac caacattttc
     7321 acccataagt tttggagatt ttaaaaatgg tggtatgtaa ggttcttgtc ttaagaagtc
     7381 tgtatacaca cccaagaata aacttgtcat agttgtattc ccagcagcca ctaatgtaac
     7441 tacatcttcc ttatctattc catttctttc atatattgtt tttaatagtg gatttatagt
     7501 ttcctcaact atagctttat gaagtgtctc taatccattt ttcttagttg aatatataat
     7561 tctatttata acatctgctc catattttat ctgtgcattt ccagaagatg ctttatctac
     7621 tacctctttt gagtataggt ctactaaaca aacaactact gaagttgtac caatatctat
     7681 tgcaactccg tataaggaat tttctttatt tccttgttct atatttatga ttgtaagttt
     7741 cttttgtttt tgaacatatg ttattgtaac cttaaaatca ctctttctaa atacagttgg
     7801 catttttcta agtatatcca atctaaaatc tatttcatta tatcctaggt tatttctaac
     7861 atatctttcc aatctatcta catcacttat attatcatct aaatttggtt cttccatttc
     7921 tatgtatttc ttttttatat ttgttttaaa ttgaaggtta tgttcttcaa ttattttttt
     7981 agctctttca aaaatttccc tatcctcttt tttattacta ccttctatct tcataccatg
     8041 catagaagat gatactttag aaggaacttc aatttctata tctgatatta cctttgtaca
     8101 acaagctagt atataacctt gctcccactc atcatctgtt atatgtcttg ttttttctgt
     8161 atcaactttt ccattcaata attttacttt acacttccca caagacacgt ttccattaca
     8221 aggagcatct atgaatatat ctgcatttct tgcaacctct agtaatatat ccccctcatt
     8281 acaataaacc tctttattgt ttggtgtaaa acttactttt atcatgttat ccctcccaat
     8341 ttgttctata tatgataaaa ggaaagtata gctaaatttg cgtgcactca aattttacta
     8401 tactttcccc aattataata atatcttaat ctttaattat tctaatccag cctcgtattc
     8461 tttatcactt aataacgtat caagttcagc cacatcagct agttttactt ttaatatcca
     8521 gttttcatat gggtcttcat ttatacattc tggctcatct tctaattttt cattaacttc
     8581 caatacctca ccattaacag gagatattaa atcagaagct actttagaag actcaactac
     8641 tccaaaatct actcccttag ttacagtatc ttctacttct ggtgtttcaa caaacaatat
     8701 ttctcctaat tgatcttgag catagtctgt tatacctata tatacaacat ctccatcaat
     8761 tacttttacc cactcatgat ctttagagta ttttaattct ggtaataatt tcatttcgat
     8821 agacccccaa tattatatta ttgattaaat tacttaaatc atattaatat tatatcatat
     8881 tattttaaat tttccatcaa ttacattaca ctttccatag ctaatgctgg atgacctttt
     8941 tcttctaaga aagctaatac tccttcagaa tcgtcagcta tagtttcatc acaaaccata
     9001 tcacagaagt tttctattcc agtcatttct ttaactgtag catttaattt atcagctaca
     9061 taatctttta attcttttgg catccaaact attctttctg gtccaccttc tgcataagcg
     9121 aattttttag aagatatgaa atgtcttccg tgtcccataa atcctggagt ttgaactcct
     9181 ccacctgtca tagaagcaag ttctccgaaa gtcataccaa ctggagtaac acttgcaaat
     9241 tctctgttaa ctacaacaaa tccatttgct tctggcatta taccacagat acattcgaag
     9301 catccacaag aagtcattgg gtcttctagt atagagtata atgtaacaga ttcaactgca
     9361 ccttgagata tttggtttac agtttcattt actgaattcc atacacctgt tctatcatct
     9421 aagcactcgc ctttttctat tggttgacaa ggacctgttg ggtctaattc tttagtagcc
     9481 ttagcatcta accagctaac tgctccacaa agaccaagtc tttcaggagt aacaacacaa
     9541 acgtgagctg gtgcaaatga ttgacataag ttacaagaat agaaagtatc aacactttca
     9601 tcaactaatg aagctaatct ttcatctcta gcattgtact tagctattgc ttctcctttt
     9661 aattcagaaa ctttttcagc atctgtaatt atagttattt cacacttatc aactactgat
     9721 tcaaattcat ctaacatctt agcatataaa acttctccta tatgctcaag tctaaatcct
     9781 ttatcaaatg catctttaga gattcttacc caagccatat ctctttgtcc aacgtgcatt
     9841 acaccttcta tatagtttaa gaagtagtgg aaacgtcttt caagaactgg ctcgaaatct
     9901 tcttgcatat ttttaccagc tattttaact attacagcaa gtggtaatct taatacacca
     9961 tctgcatcaa cttcatctat atttggtcct attatttcta tcttatggtc ttcaacttct
    10021 gttgcttctt tcttaacaac aagctcccaa gcttcagttc tgtttccacc aaactcagca
    10081 aacatatcgc tctttctaat tctctcacct tcaaatgctg ctgcaaatga aactgggata
    10141 ggtatttcag taacttttat ttttattcct ctagcttcta atgaagtagc tactatctta
    10201 tcgtaatctt tttgagttaa taggttcatt ggaacttcaa gaactgtttg gtcagttata
    10261 actgggaatc ctaaagctat tgctccagca cctgcagata caactaattc acttaatggt
    10321 ccaaatgcat taacaaatgc aggaactcta ttagctgtgt actctaataa tccgtttaaa
    10381 tcaccaggag ttaatccacc gaatattaat gctgctctta ctgcaacaga tacaacgtgt
    10441 ataacagaag ttacatcata tcctagaggt ataactctta gctcaagacc catttttact
    10501 ccagcttcta tagcttggtc tataacttta ccaactaaga aagttagtaa acctttagat
    10561 tggtaatctt ttataacttt tgctgctgat tctgcatctg gacactcacc aagaacaact
    10621 gcaacaccag gtatatctcc tgtaactaat ggtacaccaa gtgatctgat tatagggtca
    10681 gttatatgac ctgcacatgg ctcactatat ggagcatcca tagttgaata ttttaatgct
    10741 tcaattactt ctgctgctaa agctgtagct aaaccagcat taaaagcatg ttctagtaaa
    10801 tgagttctat ttattaaaga ttttactact tctaaagcac cttctaagtc ccctaaagtg
    10861 ttcatctttt gtcctgttgc agcatatata caaggtaatg aatatgctgt atcagggaaa
    10921 gcaactttat gctcttttcc attcttttct atagcttcag ctaacatagc ttgagccgca
    10981 cctaaagctt gttctgaccc tgtaaagatt atattatata gattcattct atttccccct
    11041 ttaatattta cacctatttt ttattaacta taccctaaaa accctagaaa gcaaatccac
    11101 cttcatttaa ctctaagaaa gagtctgcat ataaagatgc cccgttgatt atgtcacaag
    11161 attttacagt tttcattaat tctgggtcac atggattcat tatagctgaa ctaaatccat
    11221 tagccattgc cattgctaag aatgcactat ctaaaacagg tctaacatgc ttaggacatc
    11281 cattagatac gttagataat cctcctgtag ttaaaagtcc catctcagtc atcattttta
    11341 tagcttctaa aacttctact tgtttttctt gcataccttt tataactaag cataatgggt
    11401 caaatagtat atcagttggc tccattccta acattaagcc tttttctaat atttcttggc
    11461 agtaagccat acgctcatca ttatctcttg ggataccttc ttttgcacat aaacctataa
    11521 ccattgcttc gtattcagct gctatatcta ttaaatcaaa tcttgaacca gcatcagcag
    11581 agtttattat tggttttgca ttagttctat cataaacttt aagtccagct tcgatagctt
    11641 ttttattagc tgtatctaat gctataggaa cattgttgaa ctcagattga agtaatttga
    11701 ttccccatgt cattatttct tcgccatctc tttcggcagg tcctatatta aaatctatat
    11761 agtgtgctcc tgcttctaat tgctcttttg ctctttttaa gattggagct gggtctcttt
    11821 ctgctaatgc ttttcttatt gaaggtgata tacaatgtat tctctcacct ataatcataa
    11881 atttttccat ttataatgtc cccctttaaa tttaatatta atagttagtt aatattttat
    11941 tagtttgttt ggcatgcttt ttcttggtat ccttttaaga acttaggtaa ttccatagat
    12001 tcctctggtc ctataactac attccatcct ggtaagttat cttctatatc acctttaagt
    12061 actgcaactt ttcctggaat gataaggtct ttacaattag ttacttcttc taccttactt
    12121 tctttaatga aagcagagat tgagtttcca ccaaatttac cagcagccca agatgtaaga
    12181 actgaatatc cacctgcatc tggtattact aaccatactg gaacttttga tctttctata
    12241 tcaccagcaa ctatgaagta agttaatgca aagtcaacag taactaatac tggagaattt
    12301 tcatctgggt tgttgattgg ataaatcttt ggttcaactc tcattggtct ttgtgggtca
    12361 gtgtatatgt tttgtcttag tgcaaataat ggtaatgcct tagcataact aatatcatct
    12421 attactatta tagaaccgta ttttatagtg aatattgatg ataaagcaac ttccatcata
    12481 gggtttgaat tagataatct atttgcaaat actattgaag gatatccaaa tgttctatct
    12541 tgctctttta aagctgttct tctaacttgt atagcattag tgtaagtatc ttttatgttt
    12601 tctcctgtta catctaatac taattcttta tatccagcag cttgaattaa ttcaactgtt
    12661 tcatataatt cttctaagct accagctttt acacctaatg gtaaacttgc tcctttaact
    12721 acttctatca tatctttgta gttctcttta gttgctccat ataccattgg tctagcatct
    12781 tttaatactt caacagcttc tttaactact tgtgcatcat cacaagctaa aatataagct
    12841 acttctaatc cactgccttt tattttatct attaatttta aatacgcatc tttatctcca
    12901 caatactcta aaacagccat ttcaactttc atttgttcac caattcttac atagtcaact
    12961 tttttcatgt tagctatttt agcatctact gcttcatcac tcatacaagt acagaatgaa
    13021 actgcatatc tatttctact tactaatgtt ttttcatgtc taaataatac tgtttctcca
    13081 cctagttcat actcagatgc accagcacca acttttaaag ctttcattaa aggtgcagta
    13141 gcctctgata attttgctat agcgtcatca gacatatgtg ggcatttacc tacttctaca
    13201 gctcctgaag caaccttcat agagaaagcc atacaagttg ggaatccaca atccttacag
    13261 tttttctttg gtgttaattt aaatatatct aaagctttta atgccattat tttttccccc
    13321 taaccttaac aatttaatta agctaatgcg ttaaccaatt cttttatagt ttctattgat
    13381 tttggatgac gaagtataac tgcgtttgaa ccacctacta aaacacttgc tgcagttgaa
    13441 acttccattg ctatagttct ttcttctgga caaccccaat ctggctcatc ttctattgga
    13501 gctatagctt ctttaacatg acctacttca aaagctactg gtgttatgat aggcatttgt
    13561 aatgtcttat cattttgacc aaatgctgca agtctaattc tatccatagt agatgcaacg
    13621 tactcatatc cataaccaac tgctgaacat ccaacattca taactatatt ttcaccttta
    13681 acgcctagtt gagttaacaa tacgtttaat tgtttagcta ggtttatatc aacagaagat
    13741 tcagctccta ctttatgtgc ataagccata ccagctgatg ctcctactcc tttgtagtta
    13801 tcttctactg ctgacataaa taagcagtta tgtccatcca atgtttgagc taatttttca
    13861 aataatttac catctttttc atgatttcct gaaccagcta caactaaagg taattttatt
    13921 gcttcaatta ctgccttagc tacatcagca cattcatcaa ctgacttatc taatccattt
    13981 gggtcagaac catcaaattt taaacaaata aaatctgctt gtgtattagc ttcaacatat
    14041 ttagcccact ctactggaca attagctaca tctttgtata attccttata tgaatcagtc
    14101 cagctttcag gataaacatc tgatatttgt atccctattt ttggagaatt acctacttct
    14161 ccatcaaaac tataaaaagg taatacattt tccccaccta atttaattgc tttttcccct
    14221 attcctactt caacttctga tatttttcca gaatattttt gagtagacat tttaaatgcc
    14281 atattttttt cccccttaag cctattttaa ttctaattta gcaaaaattt ctttcatagc
    14341 cactttagat tttgaatctt caggtaaatt aactaaagga atacctgtag aatcatattc
    14401 atatatcaat tcatccatag gtacaacacc gattagctct aggttatgct tttcaatttc
    14461 ttctttaaca ccatcattca taaccccatt tggaacttta tttacaatca aaagtattct
    14521 tccaacactt aactttagtt cctcagctaa atctcttatt ctagcaacag cttgtatgct
    14581 acgtcttgag caatcactaa ccaataaaag tgtatcaaca tgtctagtga cttttctact
    14641 tagatgttcc ataccagctt cgttgtccat gactaagtat ttgtaatgac cagatatttt
    14701 gtttacttgt tctctaagta tcccatttac aaaacagtaa catccttcac cttctgacct
    14761 acccattact aataagtcat atccttcgcc ttcttcgatt atagaattta atctaaattg
    14821 aagatattgt gcctttgtca taccaccagg gaatgcattg cctaactttt ctctttgatt
    14881 tacttcttct cttatttctc ctattgttgc ttcaacttcg atacctaata cttcatttat
    14941 gttagcattg gcatcagcat ctacaactaa tactggtccc tttttgtcct taaccaaata
    15001 atcaatcaaa agccctgtga gacttgtttt accagttcca ccttttcctg caacagctat
    15061 attgtatccc attttaagac ttccccctta aatctagcca cagagcctta tgtactctgt
    15121 ctgtctatta taatttaggt acagaatgaa cacattctcc atgtacatca tgaagtgctt
    15181 ccattagccc ttcagataaa cttggatgtg gatgtattgc atcccctact tgttctactg
    15241 ttaatcctag atgaacagca agtgacaact ctgtcaataa atctgtagca tgaggtccta
    15301 ctactgctgc acctattatc ttatcagttt ctttgtcagc tataactttt acaaatcctt
    15361 ggaaatgtcc tatagcttgt gcttttccaa gacctctaaa atcaaattga cctacattgt
    15421 attctacacc ttcagcttca agttgctttt cagtcttacc aacaccagca acttcaggtt
    15481 cagtataaac acatcttgga attgctctat aatctactac cttagtctta cctaaagcat
    15541 tttcaactgc tacgatacct tctttagaag caacatgtgc taggaaagga gtatctatta
    15601 tatcgcctat tgcgtatata ccttctacat tagtttcaag atgttcatta actactactt
    15661 ttcctctttc catttcaatt cctatatctt ctactccaga attgtcaagg ttaggtcttc
    15721 taccaacaca tactaatgca tattgtgctt ctataacctt tccattagaa agagttgcaa
    15781 cagccttacc atcaactact tcacaagttt gtactccaat acctgtaata accttaattt
    15841 tatctttctt aaattgtcta agtagttgtt tagctacatc tttgtcttca tttaatagta
    15901 tttggtcaac catctcaact atagttactt ctgttcccaa ggctctaaag aactgcccta
    15961 tctcacatcc tataactcca ccacctacta ttaacataga ctcaggtatc tcttcaagtc
    16021 caagaacttc atcactagtt attacaactt ttccatcata tgggaacatt cttggtacaa
    16081 ctggaacaga accatttgct agtattatct tatctgcttt tatagtttct actgttccat
    16141 catctttagt tacttctata gtgtttttat caattaattt tccaaaacca ttaactaagt
    16201 ttactcctct tttttcaaat aagaactcta taccacttat taattggttt acaactttat
    16261 tttttctttc cattatggca gtgaagtttg gcttaactgt accatctatt tctataccaa
    16321 aatcctttgc ttcttttaca gtattcaata ctcctgaaga agcaagaagt gctttagttg
    16381 gtatacatcc tgcatttaag caagttcctc caactcttct tttttcaaca actgttacat
    16441 ctgcaccaag catagaagct tttatagctg ctacatatcc tcctggtcca ccacctacta
    16501 ctactatctt catctttaat tcccccaaac ctaatataat ctacaatctt gcaatactat
    16561 aaacctgcgg catccagtat agcaggtata ttctcttctg ccccaattgc cattatatga
    16621 acaccatcac ataaatcttc ttcttttaat tgtttgataa gttcccctgc catttttatt
    16681 ccttcactta cccagttttc ttttccagct gctcttaatc tttcgatttg ttcatctgga
    16741 acaaatattc ctggtacatt tgcagtcata aatttagcca ttcctggtga ttttaaaggt
    16801 actattcctg ctaatacctt gcaatccata tcccttgtta attctctaaa ctttctcatt
    16861 gtatttatgt cataaagtgc ttgtgtttgg aaaaatttag cccctgcttt tattttcttt
    16921 ttcattttta ataattgaac ttctattgga gaatattctg gagttactga tgctcccaga
    16981 taaaaatctg gagaaccttt taacttatta ccagccatgt ccgtacctgc cattaaagtc
    17041 tcagcagttt gaagtatccc cacagaatct aaatcaaaca ctcccttagc ttgtggatgg
    17101 tctcctacgc tagtatggtc tcctgttagt gccaacagat tgtttatccc aaatacacct
    17161 gctgacaaca tttctccttg tatagctatt ctatttctat ctctccctgt tatttgaata
    17221 actggctcta atccagcatc ttttaataat ttacatgtag caagagaagt tgctctcata
    17281 actgccgatt gaaagtctgt tacatttgct gcatgaactc ttccaactaa cggctttgca
    17341 cattctatta aatgtgaaag gtcagtccct tttggaggag ccatttcagt agtaactgca
    17401 aattttccac tttctaatgt ttctcttaat aagctcatct ctaatccccc ttttaacctt
    17461 ctaaaaaaaa cttttatgaa tttgctgctg cttctttctt tttctttgca cttaaacttc
    17521 ttggattatt ttgcttagaa tagtcttttg gtggtcttat ttctgctaag ttatctaatt
    17581 gtcctatagc ttctagtctt tcatatatct ttatccaagc acaatcattc tctgagttta
    17641 cttcacactt accattttta gctccaccac aagccccatt cataagacct ttagcacaca
    17701 tagttactgg acatatccca cctgtccaac caagttcaca gtctccacaa gccttacagg
    17761 cttcttcata ttctccaact ctttgtactt cccctataaa caaagtattg ttggctggat
    17821 aaactggctt atcttttaaa ttcttaacta ttgtctgtgt accatctcca catgctaaag
    17881 ataaaactgc atcagcttcc ttagtctctt cctttagagc ctttaaatcc tttttagact
    17941 ttaaaaggtt acaagcaggg tcaagcatta catatcctaa gatttttttg ccttcacctt
    18001 caagagtttc cttcattttt aaaacttctt cttccccacc acttttacaa gttgctgcac
    18061 attgattaca accaactaaa accagcttgt caaaatcttt taagtaccct agcacttctt
    18121 ctaatggttt attttcagaa attatcatat ctacttcccc cctaaacctt ccacatatat
    18181 atatctattt attgttttgt aatttacaag ccttaactac atgttttgca agtatagatg
    18241 ttgtaactga accaaccccc gctggaactg gagttatcat tgatactttg tctaaaactg
    18301 catttgtatc aacatctcca cataaatttc cttcttcatc aacatttata ccaacgtcta
    18361 taactaccgc tccatcttta acaaaacttt catcaaccat cttagctcta ccaatagctg
    18421 ctattagcac gtctgcctct gctgctacac ctgatagatt tttagttttt gaatgacata
    18481 ttgtaacagt tgcatgttca cttaataaaa gcattgatac tggctttcca actaccattg
    18541 atcttccaag aactgttacc ttacttcctt ttaaatcaac attatagtgt tttaatatct
    18601 caactactgc tgtaggtgta catggtggaa atccactttt atccccttcc attaccttag
    18661 cagagtttat tggactaaaa caatctacgt ctttttccgg tgcaataaca tattttataa
    18721 cttcttcatt taagtgtttt ggaagaggtc taaaacataa tataccatta acatttttgt
    18781 catcattaac tctctttaat acatcaatat attcctcttg tgttatatcc tcagctaact
    18841 ctaacacttc tgttgttata cctatgtttt gacatctctt tagtgctcct ctttcataag
    18901 ataaatcatc acttcttgcc ccaactctaa ctattgttag tttaggattt ataccttctt
    18961 taattagtaa atcgacttct tttattaatt cttcactaat cttatcagct acaggttttc
    19021 cttttataat ttgtccttta gttgacattc cttccataca ttcacaactc ccctacaagc
    19081 aaacttaaat taatttattc tatataccac atattaataa catagtatct actttcgtca
    19141 tttaaaaatt attttccaag agctttttca actttggcat aaacttcatc acaaattttt
    19201 acaccatctt caactaactt atctacttct gtttttacct tattaacata ttctttatct
    19261 tgtatagaat ttatatttat aactacattt aattgtccac caagtatagc agctcttaaa
    19321 cactgaactc ctacaccaac atcacttata gcaagtcttg aacctttatc aactaaatct
    19381 tcatgtaact taatagcttc atagcaaact cttactatgt ttaatggtac ttcacaagca
    19441 acttttaatg ccttttccat tgtttctgct tttattcttt tttcttcttc tgtttcttta
    19501 ggaagcccgt aagcttttga taatggtaag aaacattctg catcatcatc tatcattttt
    19561 aataaatctt tttctaactt tcctgcctta cttaatatct cttttacact ttcttcatac
    19621 tcagcatact tcttcttccc tattgtaagg ttacatacca tactacctaa agccatacct
    19681 attgcaccta ctagtgcagc agctccccca ccacctggta ctgcttcttt ggaagatagt
    19741 acttctacaa aatcaacaca agttttatct gctattttca tgataatcct ccttgaaagg
    19801 atgtaggaaa atatctcaaa ttgttcgaga tattttacga actattttaa gatatctcct
    19861 actctttatt tataaattaa tttccttaga ataatccagc tattactcca ttttcatcaa
    19921 catctatttt ttctgctgct ggaacttttg gtaatcctgg catcttcatt atttctccag
    19981 taagtgcaac tataaatcca gctcctgctg aaattgttgc ttgtcttaca gttattctaa
    20041 atcctgttgg tctacctaat ttagtttggt catcagttaa agaatattga gttttagcca
    20101 tacatactgg aactttagta aatccaagtt tttctaagtt agctatttcc ttatcagctt
    20161 caggagtata atctacacca tctgctccat aaatcttagt agctatagca tttatcttgt
    20221 cttttataga taaatcatct tcatagcaga atctaaagtt attttcttct tcatccaata
    20281 atcttaaaac ttctttagct actgcaattc caccttctcc accttttgcc catacttcag
    20341 aaagagcaac attaacacct aattccttac acttgtcttc aacaagttta agttcagctt
    20401 cagtatcaag tgggaatcta ttgattgcaa caactgctgg taatccatat acttgagtta
    20461 tgttttcaac atgttttaat aagtttggaa gtcctttttc aagagcttct aggttttcgt
    20521 tatttaagtc tgctttagca actccaccat tgtattttaa tgctcttaca gtagcaacta
    20581 ttataacagc atctggtttt aagtttgcca ttctacattt tatatctaag aatttttctg
    20641 ctccaaggtc agcaccgaaa ccagcctcag ttattacata atctgcaaag tgcatagcca
    20701 ttcttgtagc tataacagag ttacatccat gagctatatt tgcgaatggt ccaccgtgta
    20761 caaatgatgg tgttccttca agagtttgaa ctaggtttgg ttttaaagca tcttttaata
    20821 atgcagccat agcaccatta gcttttaatt gtctagctgt tacaggttca ccttcgtagc
    20881 tgtatccaac tattatgttt cctaatcttt cttttaaatc agatatatca cttgccaaac
    20941 agaacgctgc cattatttca gaagcaacag ttatatcgaa tccatcttgt ctaactgctc
    21001 catcaccttt tttacccata ccatcaacga tatttctaag ttgtctatcg ttcatgtcta
    21061 cacatcttct ccaagttatt ttcttagggt ctattctaag tgcatttcct tggtgaatat
    21121 ggttatcaag catagcagct aaaagattgt tagcagctcc tatagcgtga aaatctcctg
    21181 tgaagtgtaa gtttatatct tccataggaa caacttgtgc atatcctcca ccagctgctc
    21241 cacctttaac accaaatact ggtcctagag atggttctct taaagcaact aatacatttt
    21301 tgtctagttt agcaaatgca tcagcaacac ctatagtagt agtagttttt ccttcacctg
    21361 ctggagttgg gtttatagct gtagttagta ttaacttagc ttttttacca gtctctcttt
    21421 ttagtagatt gtagtcaact tttgctttgt atttaccata aagttctaca tcatcttcac
    21481 ctagtcctaa tttttttgca acctctctaa tatcttgagg cttagcttct tgagctattt
    21541 caatgtcaga tttaaatccc ataactgaat ctcctcccac aacctaaata gatttaaaat
    21601 ataatttttg taaaaattgt attaatatgt aaaaattata ttttataaga taattataca
    21661 tgtaaaatta cttaaaaact agctactaag ctattaaaat attcaaactt aatagctagt
    21721 tatttatcta attacttact tattacctat ctattgccta tgtctaacct ttaaccaact
    21781 taaaatccca aatcaaaatt tctatctatt ttacttatcc ttaagtgaca ttaatttatc
    21841 ttttattgct ttaatctgtt ctttcgttgt ttcactagaa tcatatggag attgattagc
    21901 tctatcagaa tcaataacat cttggttata ataaataaat cctaaagatt ctccatcttc
    21961 taagttttgg attataaatt cttcatcttc cttatttcta attttatttc ctactacaaa
    22021 tactttattt acacctatat catgtccaag tttcttaact tttctataag tctgtagact
    22081 tctctctcct ggttctacaa ctactataaa agcatctaca ccttgggctg ttcctcttcc
    22141 taagtgttca attcccgctt ccatatccat aaccactaca tctttatttt gtagtattaa
    22201 atgtgagcag agtctcttca aaagaacatg ctctggacat acacatccag taccaccaga
    22261 atctacggtt cccaatgtaa gtaatcttac tccattgtat tctttacaga aattttcagg
    22321 gatatcgtct actttaggat tcatcttaaa catttttcca aatgaaccta cagaagcagc
    22381 tgttctatct gaaactaatt ttttcatttc tgatataggt actattgatt catatacttc
    22441 ttttggaaaa cctagtgct
//
LOCUS       DAGQVA010000064        22382 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.064, whole genome shotgun sequence.
ACCESSION   DAGQVA010000064 DAGQVA010000000
VERSION     DAGQVA010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22382
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.064"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            37..957
                     /locus_tag="MIV85_002737"
     CDS             37..957
                     /locus_tag="MIV85_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBY2962066.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            1072..2229
                     /locus_tag="MIV85_002738"
     CDS             1072..2229
                     /locus_tag="MIV85_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBY2962067.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(2310..3206)
                     /locus_tag="MIV85_002739"
     CDS             complement(2310..3206)
                     /locus_tag="MIV85_002739"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBY2962068.1"
                     /translation="MLKKVKYPIGQVKVSDKFKTIKLLSRKYSISSMCKLISVSRSGY
                     YKWLSYSKKSSDRGIKDRIIKDYIIEIHKKYRGTYGRKRICTYLNKILDTPINHKRVY
                     RLMKELGIKSIIRKKVYRRKFKSYEIYDNILNREFRANQPLEKICMDITYIPIGKKFL
                     YMNVAKDLFNGEIVAYEISTKMDTKLVNNTVNQLINMNLAKDCILHTDQGSQYTSRSY
                     SKRLKDNGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPKEMISLINDYIYF
                     YNNERIQLKNGMSPIEYRTHSE"
     gene            complement(3164..3481)
                     /locus_tag="MIV85_002740"
     CDS             complement(3164..3481)
                     /locus_tag="MIV85_002740"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBY2962069.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQN
                     WVKDYKNKGKTAFDDETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLD
                     KSK"
     gene            complement(3618..5117)
                     /locus_tag="MIV85_002741"
     CDS             complement(3618..5117)
                     /locus_tag="MIV85_002741"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBY2962070.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIEDEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            5713..7137
                     /locus_tag="MIV85_002742"
     CDS             5713..7137
                     /locus_tag="MIV85_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBY2962071.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANESEEDSTSLEEAKAKMSDMKSASKNSEKNIEKKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLDIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            7172..9301
                     /locus_tag="MIV85_002743"
     CDS             7172..9301
                     /locus_tag="MIV85_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBY2962072.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFSLASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIIK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKGKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNTKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIMSIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDE"
     gene            9331..9753
                     /locus_tag="MIV85_002744"
     CDS             9331..9753
                     /locus_tag="MIV85_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2962073.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAK"
     gene            9772..10923
                     /locus_tag="MIV85_002745"
     CDS             9772..10923
                     /locus_tag="MIV85_002745"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBY2962074.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEIYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEAHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSNGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      11029..11130
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            11313..11885
                     /locus_tag="MIV85_002746"
     CDS             11313..11885
                     /locus_tag="MIV85_002746"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBY2962075.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKEEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            11949..12599
                     /gene="fsa"
                     /locus_tag="MIV85_002747"
     CDS             11949..12599
                     /gene="fsa"
                     /locus_tag="MIV85_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBY2962076.1"
                     /translation="MIFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHEGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            12751..15675
                     /locus_tag="MIV85_002748"
     CDS             12751..15675
                     /locus_tag="MIV85_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2962077.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKEPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPVLNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            16252..16710
                     /locus_tag="MIV85_002749"
     CDS             16252..16710
                     /locus_tag="MIV85_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2962078.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            16771..17046
                     /locus_tag="MIV85_002750"
     CDS             16771..17046
                     /locus_tag="MIV85_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2962079.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            17105..18379
                     /locus_tag="MIV85_002751"
     CDS             17105..18379
                     /locus_tag="MIV85_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBY2962080.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            18509..19561
                     /locus_tag="MIV85_002752"
     CDS             18509..19561
                     /locus_tag="MIV85_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBY2962081.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            19561..20592
                     /locus_tag="MIV85_002753"
     CDS             19561..20592
                     /locus_tag="MIV85_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBY2962082.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            20684..21496
                     /locus_tag="MIV85_002754"
     CDS             20684..21496
                     /locus_tag="MIV85_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBY2962083.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            21499..>22382
                     /locus_tag="MIV85_002755"
     CDS             21499..>22382
                     /locus_tag="MIV85_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBY2962084.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTT"
BASE COUNT         8931 a         2551 c         3991 g         6909 t
ORIGIN      
        1 ttaataatat tagtgaaaat gaaaggatta taaaatatgt ataaatcaga aaatttttca
       61 aaaaaatctg tattaataaa ttcattttta agtaaatttt taaaaataat tggatggggt
      121 ttggtaagct tatttacatt atcagcctta gtactttcaa ctatttccat tataattgga
      181 tgggctgtaa tacttcctat tcaagtatgt gcagtatttt tacttatagg aggagtttgt
      241 atttttaaag gtaagagatt aggagaccaa atttctcgtt ataaaaaata ttgtacaatt
      301 ataaacaata gaaatattat tccagtagaa cttattgcag aaaacacatc taaatcatta
      361 aattttataa taaaagatgt acaaaagatg atagacaaaa actactttat aaatacttat
      421 attgataaaa gaaataatca gattgtgtta acaaatgaag attttgttcc accaagatat
      481 gaagatgtag catatgaagt caaagaagaa gaaaagactg atgaatccaa tgaagttgat
      541 acaattataa ataaaggaat gaattatcta acacaaataa aagaagctaa taaaaatatt
      601 aaatcagaat caatgggcga taaaattgta caagtagaag atgttacaag taaaatattt
      661 gatgttgtaa aacatgaccc atcaaaactt actcaaatac aaaaatttat ggattattat
      721 cttccaacca ctttaaaact attaaattca tatcatacat tggaagaaca aggaattgat
      781 agagaaaata taacaacaac tatggaaagt attgaaaata caatgaatac gattgtagta
      841 gcttttgaaa atcaattgga ctatctgttt gaagatgaag ccattgatat ttctacagat
      901 attactgttt tagagaatat gttagtccaa gaaggattaa cgagtggtaa attttaactt
      961 caatagaaaa aatattctgt tatttttaaa caattaatta gtcataaagt ataaaatgtg
     1021 tattatataa gttaatcagt actttatgaa ggaagaggag agaaagatac aatgaataat
     1081 ttagatgata taccagttat gccaactttg acacttgacc catttggaga agaatcaaac
     1141 actaatgata tagataattc tgacttatta atgaaaaagg atgaaaaaga cccagaagaa
     1201 gaaaaactgt ctgaatctga acgcaagatg gtaaaggaat ttgcggaaaa aatagatatt
     1261 acaaatacaa atatgatttt gcaatatgga gctggtgctc aaaaaaaggt agcaagtttt
     1321 tctgaaacag ctttaaagag tgtaaagaca agagatttag gagaagttgg agatatgctt
     1381 acaaatctag ttactgattt aaaagcattt tcagcagatg aaaaagaaca aagtggtttt
     1441 ttaggaattt ttaaaaaggc aaataataaa atttcaaatt taaaaactaa gtatgatagt
     1501 gcagaggtaa atgtggataa agtaagcaaa gagcttcaaa agcatcaggt taaaatattg
     1561 aaagatatag caatgcttga taagatgtat gaattgaact tagcttactc aaaagagctt
     1621 actatgtata ttatagcagg aaaacaaaaa ttaaaggata tgaaagaata tgagatgcca
     1681 aagttgagag aaaaagctcg tttatctggt tcaacagaag atgctcaatc tgtaaatgat
     1741 atggtttcac tttgtgacag atttgaaaag aagattcatg acttagaatt aactagaatg
     1801 gtatcgcttc aaatggctcc tcagataaga ttggttcaaa atagtaataa tctgatggca
     1861 gaaaagattc aatcaactat agtaaatacc attccattat ggaaaaatca aatagtgctt
     1921 gctcttggaa tttctcactt aaatcaagct atgaaagcac agcgtgaagt tagtaatatg
     1981 acaaatgagc ttttattaaa gaatgcagaa actttgaaga tgggaacaat agaaacagca
     2041 aaagaatcag aaagaggaat tgtagatata gacacaatta agaaaactaa tcaatctcta
     2101 atatctacta ttgatgaggt agttaagata caacatgatg gtagaataaa gagacaagaa
     2161 gcagaagttg aattatcaaa aatagaaaat gaacttaaaa gcaagcttct tgaatttaca
     2221 gttaaataaa aattatacta agataaaaag agactgtctc aaaattggat atgtccctgt
     2281 caagtagaca gacttaaaaa aggctatctt tactcggaat gagttcgata ttcaatcgga
     2341 ctcattccgt tttttaattg tattctttca ttattataaa aataaatata atcatttatt
     2401 agactaatca tttcctttgg atctgtagta tcaattaaat atattaattc agatttaaaa
     2461 tgactgaaaa aactttctat aggagcatta tcccagcagt tgccccttcg ggacattgat
     2521 tgtataatac cattatcctt aagcctttta gagtaagatc tacttgtata ttgtgaacct
     2581 tgatctgtat gtaaaataca atctttagct aaattcatat ttattagttg atttactgta
     2641 ttattaacta atttagtatc catttttgta cttatctcat atgccactat ttcaccatta
     2701 aataaatctt tggctacatt catatataag aattttttac cgataggtat gtatgttata
     2761 tccatacaaa ttttttctaa tggttgatta gctctaaatt cacgatttaa tatattatca
     2821 tatatctcat atgatttaaa cttacgtcta tatactttct ttctaataat agatttaata
     2881 cctagttctt tcatcaacct atatactctc ttatgattaa taggggtatc aagtatttta
     2941 tttaaataag tacaaattct ttttctacca taagttcctc tatatttttt atgtatttca
     3001 attatataat ccttaataat tctatctttg atacccctat cggaagattt tttagaataa
     3061 cttagccatt tatagtaacc gcttcttgac acacttatca acttacacat actagaaata
     3121 ctatacttcc tagacagaag tttaattgtt ttaaatttat cgcttacttt gacttgtcca
     3181 atagggtact taactttttt aagaattcat tctccatgcg taagtacttc aattcttctt
     3241 caacagattt aaattttcta ttatcatttt ctagactaat atttttaaat ctgcccctag
     3301 tttcatcatc aaatgcagtt ttgcctttat ttttataatc ttttacccag ttttgaactt
     3361 gtgttttgct tcttatattc agcatctcag caattttgta tgatgagtat ccttctttta
     3421 tatataagtt tacagctttt agcttaagtt ctttgctata ttttttgtgt tttttagaca
     3481 tagaaaaacc cccttagagt atacgctttt tagacctatt ataatagcct tttatttaaa
     3541 tgtctactat aaggggatta tactaaaata gagataagtc tctttttcat tgtttaaatg
     3601 attaaagtat atttatatta taaatttcta ttatctttta acataacatc atgagctcca
     3661 ccttcaacta tactagtaga agatacaagt gtaagtttag catttttttg aagttcagga
     3721 atgctaagtg ctccacagtt acacatagta gaacgaactt tacttaaaga aagagttaca
     3781 ttgtctttca aagaaccagc ataaggaaca taagagtcaa caccttcttc aaaagaaagt
     3841 ttcttatctc caccaaggtc atatctttgc cagtttctag cacgagcaga accttctccc
     3901 caatactctt tcatataact accatttata ttaactttgt tagttggact ctcatcaaaa
     3961 cgagagaagt atctaccaag cattataaaa tctgcaccca tagctaaagc taaagttata
     4021 tgatggtcat aaacgatacc accatcagaa caaattggaa tataaatacc tgttttttca
     4081 aagtattcgt ccctagcttg agcaacttca attatagaag tagcttgtcc acgtcctata
     4141 cctttttgtt cacgagttat acatatagaa ccaccaccaa taccaacttt aacgaagtca
     4201 gcaccagctt cagctaggta aaggaatccc tcacggtcaa ctacatttcc agctcctacc
     4261 ttaactgtat caccatattt ttcacgaatg aaatcaagtg ttattttttg ccactcagaa
     4321 aaaccttctg aagaatctat acataaaaca tcagcaccag cttcaactaa agcaggaaca
     4381 cgttcagcaa agtctctggt attaatacca gctccaacta catatctctt agaagaatct
     4441 aaaagttcaa gtggattttc tttatgagaa gagtaatctt tacggaatac catatacata
     4501 agattaccat tgtcatcaag tacaggaaga gaattaagtt tgtggtccca tataatgttg
     4561 tttgcttcct ttaaagtaac atctttgtta gcataaacta tagatgacat aggagtcata
     4621 aattcactaa ctttagtatc taaatccata cgacttatac gataatcacg acttgcaaca
     4681 atacctaata atttaccagt tgaagttcca tcttcagtaa cagctactgt agaatgtcca
     4741 gttttttctt ttaagtcaag tatgtctttt aatgtgttat caggtttaat atttgaatca
     4801 cttacaacaa aaccagcttt gtgggattta acacgtgcta ccatagcagc ttcatcttca
     4861 atagtttgag aaccgtatat aaatgaaata ccaccttctt tagcaagtgc aatagccatt
     4921 ttgtcatcag aaacagattg cataatagca gaagtcaaag gtatattcat ataaatatct
     4981 gcttcctcgc cctttttaaa tttagtaaca ggtgttttta aacttacatt agcaggtata
     5041 caatcagtag aagagaaacc tggtacaaga aggtattcac tgaaagtatg tgatggtgta
     5101 tcaaaataaa acgccatttt ttaatcactc cttatatttt tatacttttt ataattgata
     5161 gtattaatta taacttattc tttaatttta ttaaagtatt ttgtcaaata ttgagatttt
     5221 tgaaaaattt aaactatttt aattgaattt gtttaatata tattgcctta tagggtaaag
     5281 ttgtatatta aataatgttt agtgtttaat agtagctaat ttgaaattaa tctttagtta
     5341 ttcatataat tacatttgta tagtttatat tgataatatt gctagagagt gcataaacct
     5401 caaaaataca gataaattaa atctatatta gtatatccaa aagtacattt aataaattta
     5461 tttaactgaa ttattatttt catttctatt aaatttaaat attttataaa aatagtatta
     5521 tttacaaaat catatactcc aaaatactac ataaataaaa ttaaacaaaa actaaaatga
     5581 caaatgtcat tatctaaagt gacatagaaa cggtttctta aagttgttac tataaaatat
     5641 aaactctata ataaaagtat aacaaaaggg aatcatatcg atatagaata taattcaaga
     5701 ggaggtaaaa ttatgagtag ttctaatcaa tcgacaataa agacatctat acagcgagta
     5761 gggaaatttt taagtggtat ggtaatgcca aatataggag cttttatagc atggggtctt
     5821 ataacagcat tatttatacc aacaggatgg atgcctaatg aaaaattgag tactataggc
     5881 gacccaatga taaaatacct tttaccacta ttgatagctt atactggtgg taaagcaata
     5941 gcaggacaaa gaggtggcgt aataggtgca gcagcagcta tgggagtaat tgttggggca
     6001 gatataccaa tgtttatcgg agcaatgata atgggaccat ttgcaggatg ggtaattaag
     6061 aagttcgata aatttgtaga tggaaagata ccaacaggat ttgaaatgtt agtaaataac
     6121 ttttcaatag gtataatagg tatgcttctt gcaatactag gattttatgc aattggacca
     6181 gcaatagtag cagggacagc tcttatagaa tctggagttc aatttatagt tagcaaaagt
     6241 ttattgcctt tagtttcagt atttatagaa cctggaaaag tattattctt aaacaatgca
     6301 ataaatcatg gtatattagg gcctataggt atagctgagg caaaagaagc aggtaaatct
     6361 ataatgttct tactagaaag taaccctgga ccaggtttag gagttctatt agcatattgg
     6421 atgtttagta gaggaagtgt aaaacaatca gcaccaggag ctgtaataat acatttcttt
     6481 ggtggtatcc atgaaattta cttcccatat attttaatga atccagtttt aatattggct
     6541 acaatggcag gtggagcagc aggaatattg actttttcaa tattaggagc tgggcttgta
     6601 gcagcaccat caccaggaag tatatttgca cttatggcac tagctccaaa gggaggatta
     6661 cttccagtat tagcaggggt tgcagtggca acagttgtat cattcttagt ggcagcacca
     6721 tttgttaaga gagcttcagc aaatgaaagt gaagaagaca gtacttcttt agaagaagct
     6781 aaagcaaaaa tgagtgatat gaaatctgca agtaagaact ctgagaaaaa tattgagaaa
     6841 aaacagcttg aagtaaatga gattaagaag attgtatttg catgtgatgc aggaatgggt
     6901 tcgagtgcaa tgggagcttc tagatttaaa aatagaataa aaaacttaga tttagatata
     6961 gaaattacaa attcatctgt tgataatctt ccagatgata cacaaatagt agtaactcac
     7021 aatacattag ttgaaagagt tgctaagaac aattcaagtg ttgagatagt ttcaataaac
     7081 aattttttaa atgacccaaa tttagataca ttatttaaaa gattagaatc taaataaaaa
     7141 taaaaagtac cactaattag gagtggataa tttgaaaaaa aagaagatta catctaggca
     7201 aaaaaagata atactaatga tagtagaaaa ttcaaagaaa aacattccaa taactatttc
     7261 tgagattgca gggacgttag agttaagttc aagaactgta cttagagata tgtctggaat
     7321 tgaaaaatgg tttgatgaaa atgattttaa ctttgtaaaa aaaccaggag taggattgat
     7381 tttagaggaa aatatagaaa atcaaaactt tataattgag ttgttagaag aagaaaaaat
     7441 agaaaaagaa tacagcaagg aagaaagaaa tttaattata ttatcaaagc tactagtttc
     7501 taacgagcca gtaaaatctt attattttgc aaaaatatta aaggtatctg aaggggtact
     7561 gaataatgat ttttcattag caagtaaatg gttggaaaga tttgatattg agcttgttag
     7621 aaaaccaggg cttggtgtct acctaaaagg tcaagaaaaa agctttagag aggcatatgt
     7681 aaatcttata tacgattcat tcaatgaaaa agaaatacta gatatggtca gaaatataag
     7741 tgaaaatata caaacagata aagcaataga aattttaagt gaaaatagac ttttaaattt
     7801 aatggatagg tgcataataa taaaagttga agctacatta acaaagaagc tttcagattt
     7861 agatgtaaat ttagctgata gtgcatatat agggcttgta gttcatattt cattagcctt
     7921 acagaggata aaaaatggtg aaaatataac tatggataaa gagtttctaa aagaattatc
     7981 tataacagaa gagtttaaat tagctaaaga aatcgtaaaa ggtatggaaa cagattttaa
     8041 catggatata ccagtagatg aggttggata tataactatg catataagag gtgcaaagca
     8101 aaggtcatct tcaaatcata aggctttaaa cttggatgat atagaaataa tggaaattac
     8161 aaataagatg atagatttgg ctgaagatga atttaaaata agtttaaaaa atgacgagag
     8221 gttatttaaa gacctagcaa atcacttagg accttctata aatagattga atatgggatt
     8281 agaaataaga aatcctcttt tagatgaaat aaaaagcaag tattcatatg cctatgatgg
     8341 agttgaaaaa atttctagaa ttataaaaga taaactaaat ataaattcaa tacctgaatc
     8401 agaaatagga tatattgcaa tgcactttgc atcagccata gaaaaaaatc ttatgatgaa
     8461 tactaatata aatattgttg tggcatgtcc cactggaata ggtacttcaa gattcttatc
     8521 aactaagatt gaaaataaat ttcctaattt aaatatactt gaaaccatat cagctataaa
     8581 catagatgaa gagtatttaa agggaaaaga tgttgattta atagtgtcta cagttgagtt
     8641 aaatacaagt ttaaattata tatgtgtagg tccatttatg agtttagatg atgaacagat
     8701 aatcaaggaa aaaataaaat ctatagctca aaataaatta attaatttaa atacaaaaaa
     8761 tgatactaaa agtaagaata aagtatatga acagataaca gaaagtatga atataggaaa
     8821 agatattctt caatttttag aggaaattag atttgaaaaa tttgaaagta aagatttaag
     8881 tgagcttatt gaagactcat caaaaatatt tgcaaaatct agtgaagata taatgtctat
     8941 aaaagaatcg ttaaaagaaa gattaaaaat ctcaattcca tatatagaag aatcaaaaat
     9001 tctattatta cattgtatga gtgaaagaat agatattatg aagttatcaa taataaaact
     9061 ggagaatcga atcgtgctag attcaaatga agaaatcgac aatgtagttt ttatgttact
     9121 tcctaaaaat tcaccaagtt atcaaagaca aataatgagt gaaataagtg gttcattaat
     9181 agacaatata atttttacta ataagataaa taaattctct atagaagaga tgacattaga
     9241 ggtaaaagat atagttttta atttttatac aaacagatta aaagcattta tagatgaata
     9301 aaattaatat taaaaaggaa ggttgatact atgagtaaag tattgaatga gaataatata
     9361 tttttagggt tagatagtgt ttcaaaggaa gaagctataa ctttagcagg aagaaaatta
     9421 gttgaaaatg gatatgtaaa agaagaatat ataccagcaa tgctagaaag agaaaaagta
     9481 atgactacat atatgggaat gggagttgct attccacatg gtgtaaatga agcaaaaaaa
     9541 gaaatattat cttctggaat agttatacta caattcccta atggtataga ttttgatgga
     9601 gaaaaagcat acttattaat aggaatagct ggtgttggag atgaacattt agaaatacta
     9661 tctaatatag cagtagtttt agatgatgac ttaacagaaa gactaaaaaa ttcaaatgac
     9721 aaacaagctt ttatggaagc ttttgccaaa taatcttagg agggatttaa aatgaaaaag
     9781 gcaatccagt ttggagcagg aaatattgga agaggtttta ttggaggctt gttagttaag
     9841 tcgggttatc atgtagtatt tgctgatgta aatgaggaga tattaaactc aataaataaa
     9901 gataaaaagt atactataca cataagagat gtagaatgta tagatgaagt aattgataat
     9961 ataagtgcgg tttcatctat aaaagaagaa ataatagatg agattgtaca ggctgaaata
    10021 ataactacag cagttggacc tttagttttg actaaaatag cctctacaat tgcaaaaggt
    10081 ataaaggcta gaaaagaaaa gggtttaaca agtaatctaa atataatagc ctgtgaaaat
    10141 gcaatatacg caagttcttc tttaaaagaa gaggtactta agtatttaaa taaggaagaa
    10201 gtagaatatt tagagatata tgttggtttt ccaaactgtt cagttgatag aatagttcct
    10261 cctggtaaaa atgaaaatcc tcttgatgta acagttgaaa atttttatga gtggaatgtt
    10321 gaaaaacaag gatttaaagg ggaaatacca actatagttg gaatgaattt agctgacaac
    10381 cttatggctt atatagagcg taaattgttt acactgaata caggtcatgc tataacagct
    10441 tatataggat atttaaaagg atataagact atagaagaga gtataaaaga taaatttatc
    10501 tgtgatatag tcaaaagtgc aatggtagaa agtggagaag gattgattaa aaaatacaat
    10561 tttgactcag aagcgcacta taaatatatt gataaaattt taaatagatt taaaaatcca
    10621 tatcttaatg atgatgtatt aagagttgga agggaaccat taagaaaact aagtgataaa
    10681 gatagattga ttaaaccttt aatgacagca aaatcatatg gattatcagt tgacaatttg
    10741 attcttggaa taggtgcagc gcttcattat aataatagtg aagatactca aagtgtagaa
    10801 ttacaagagt tgataaagtc taatggtgta aaaaaagctg ttgctaaaat agctaatata
    10861 agcaatgacg aagaactttt aaataatatc gaaaaaagtt atatatttat gaaaaattta
    10921 taaatttact tgaaaaaaag tagttctgat aaagtaacta taatatatta ttctacacag
    10981 tttgaattat ttgttgaata atagagaatt ataatatata attaaaagga ataaattaat
    11041 atatttacct gtatatgttt gataatatgg ttcaaatgtt tctactaagc taccattaat
    11101 agcttgacta caggagtgaa gaagatatag tttatactta ttttaaatta tatattaagt
    11161 taattacttt gaattttaag ctcctgtcta tgatatagac aggagctttt ttagtatttt
    11221 aatataaaat acttacaaga atagatagca aaattagaac aaatataatt tttttattaa
    11281 tataacttta gaaagggcta ggtggaagtt caatgaaggc tttacaagaa aagatattga
    11341 gagaaggcag tgtttcagga aatgatatac taaaagttga tagtttttta aaccatcaaa
    11401 ttgatgtagc ttttttaaat gaaataggaa gagaatttaa agagagattt aaagaagaaa
    11461 aggtggataa gatatttaca atagaggctt caggaatagc tatagcatca attgtttcac
    11521 agtattttga taatgcacct gtagtatttg caaaaaaatc agaatctaaa aatttggata
    11581 aagatgtata tgagactaat gtatattcat ttactaaggc aagagaatat tcagttaaag
    11641 tttctaaaaa gtacataaac aaaggtgaaa atatattgat agtggatgat tttttggcaa
    11701 atggaagagc tgctcttgga cttaaagatt taattgagca agcagaagct aatttagttg
    11761 gagtaggaat tgtcattgaa aaaggatttc aagctggagg agcactttta aaggctaatg
    11821 atgtaagatt agagtctttg gcggtagttg aatctataga taatggaact gtaaaattta
    11881 ggtaatttat gatattatat acttgtgttt agcacatatt ttaactatgt aattatggag
    11941 gattttttat gatatttttt atagacacag ccaatattga agaaataaaa gaagcaaatg
    12001 atttaggtgt aatatgtggt gtaactacta atccatctct aatagctaaa gaaggtagag
    12061 attttataga ggtagttaaa gaaataagtg aaatagtaga tggaccaata agtgcagaag
    12121 taataagttt agagcatgaa ggtatgatag aggaagcaga aaaattatct aagatacata
    12181 aaaatatagt tataaagata cctatgacag cagaaggtct aaaagcggtg aaagtactat
    12241 caagtaaagg tataaaaact aatgtaacac ttatattctc tgctggacaa gctcttttag
    12301 ctgctagagc tggagctaca tatgtaagtc cttttgttgg tagattggat gatatatcac
    12361 aaaatggtct tgatttaatt gaagaaatcg ttgatatatt tagtgtaaat agtattgagg
    12421 ctcaaataat agttgctagt gttagaaatc caatacatgt tttacaagct gctagaatgg
    12481 gagcagatat agcaacagtt cctcttaaag ttataaacca aatgattaag catcctttga
    12541 cagacaaagg aatagatagc tttatgaagg attgggaagg tgcttcttta aaattataat
    12601 tataaactac gctttataag tatattaaag aggttattat ggaaattcta agtaataagg
    12661 ctaggctatt ttgcctagtc ttattttggt gtataatata ttgaaacata ttattgaaat
    12721 agattaattt tttaagtgag gaggcgaaaa atggataaaa tattaagaga gatacaaaga
    12781 gaagataaaa aaaatccata tactgaccaa gaacttgctg aaatgttaaa tgtagctagg
    12841 tctgaagtga tatcagtgag gaaaaaaaat aatattttag attcgagaga aagaagaaaa
    12901 aaaatattaa taaaagatat atcaaaaatt gtaagtgaaa atcctcaaat gtctgaaaga
    12961 aaaataactg agatattaat agagaatgga tataatatat cgagaagtgc agtttcaaaa
    13021 ttattaaaag aagaaaattt aaatcagtca aagattggga ttaaagataa agagccagca
    13081 tcatcaggaa agtatgtgaa ggtgagtaaa gttgtagaag aagatggatt tgaagaattg
    13141 ataggtataa agggaagttt gaaagaaaag gtaaatctag ctaagtcagc aataatgtat
    13201 cctcctaatg gccttcatac tataatatat ggagaaacag gggtaggtaa aagtgaatta
    13261 gctacatgta tgtataaata tgctataaaa aacaacatca aagaagagaa cagcccattt
    13321 atagtgttta actgtgcaga ctatgcagaa aatcctaatc tattgatagc tcaactcttt
    13381 ggggtagtaa aaggtgcata tacaggagct gatgcaaata gagaaggtct tgtagaacaa
    13441 gctaataatg gaatattgtt tttagatgaa attcatagat tgcctgctgc tgggcaagaa
    13501 atcttatttt cattaataga tagaggagaa tttagaaggt taggagaaag tagttctaat
    13561 agaaaggcaa atgttctcat aataagtgct acaacagaaa acccagattc taatttactt
    13621 caaacattta gaagacgtat accaatggta ataaatttac ctaatatgag tgaaagacca
    13681 aaatctgaaa gatatgaaat aataataaag ttttttgaaa gagaagcaaa gcgagtaaac
    13741 aagaatttta taataactaa agaagttatg tgtgcactta tgaattataa gtgtactgga
    13801 aatataggtc agttaaagag tgatatacaa gtaacttgtg ctagagcttt tagtaaatca
    13861 atattttcta gcgataaggt aattatagat ttagatagtt taagggatta tataaaaagt
    13921 ggatattatg attgtaattg taaaaatgaa aagtattctg agttttcagt tgaggatata
    13981 tatatagata tcagtgaatt ggtgagtgga aaaaatagaa ttttatctga taatgagata
    14041 agcgagatat ataattatgc agaaaaagag cttaaggttt tggaaagtaa gtgtttttca
    14101 gaagaagagt taaaaaatgc atttatagaa aagttagata agaagtttaa tgctattaaa
    14161 aacaataaaa atttatctga tagaagaagt cgaatagact ggggaggaca attaaaagag
    14221 tctacattgg agataatgga taaggtaatt gtatttatta aggagcagtt taagcatgta
    14281 aatcaaggat tgtacttggc tctagcaatt cacattgagc atgctatagg taggataaaa
    14341 gatggaaaaa ctataataaa tccgagttta gataaaataa aagcatcaat gccaatggaa
    14401 tatgaattgt caagatatat aatgggtata gtggaagatt tgacacaagt aacatttcca
    14461 gaagatgaac ttggatattt ggcttattat ataaataaat tttgttataa tgaggaaagt
    14521 ataaaagata aagttaaagt agtaatagtt acgcatggta aagttggaat tgaaatgtct
    14581 aaagttgtaa atcatatttt aggtatagaa tgtacactag gtatagaaat agcacttaca
    14641 gattcaccat cagaggggat agagcatgta ttagaagagc ttcaaaagat agaagctaga
    14701 aaaggtattc tagttctaat tgatatgggt tctttggtaa ttcttggtga tgaggttgaa
    14761 aaaagacttg gaattagatg taaaactgta aacagagtag atacgttatt ggcaatggaa
    14821 gcaggaaaac ttgcaaccat tgaaggaaaa agtttagatg gtataatagc agatttaaag
    14881 aaaaataaga attatgccat gataaataca aataaattta gttacagaaa aaacgagtat
    14941 ggaaagaaaa atgtaatcat tactttatgt ttgagtggtg taggtacagc tttaaattta
    15001 aaagagcata tagaaaaaca aattaaggaa tatgacactt taattgaggt aaagccagtt
    15061 gcttttttaa ataataattt agaagaagag ttaaatgata ttgaagctga atataatatt
    15121 attgctatct gtggaactat cgatatagat tataaaaacg taccttttat ttcttataat
    15181 gaggtacttg gtaaaaatgg tattaataaa gtattagagc atttaaacag taaacaacca
    15241 gttttaaata ttgaaaacca gttgaataat ttaatacatg aagatttgat tttatacaat
    15301 tttgaaggaa tttcaaagga gtatataatt gatactcttg tttcaaagct tgaagaaggt
    15361 ggatatgttg actcaaagta tatattaagt gtatataaaa gagaagcaat gggaagtgtt
    15421 gtaatggcct ctaaggtagc cgtgccacat ggacttccag aaaacgttat aaagcctgca
    15481 atagcaatcg caaggttgaa taagcctata gtgtgggaca ataaatttat ggtggatttg
    15541 gtagtactac tggcacttaa agaaaataat aagaaagaaa tacgaagctt attttcaaag
    15601 attaatgacc aacatacttt agaagtttta ttaaatactg aagataaaaa tgaaataaaa
    15661 gaacttttaa gctaattatt agtacagaga agaaagacaa aaaatttgct ttagtataaa
    15721 atttaaaact acttaattgc taagtagtta attactcgat ataaggctag ttctatgaaa
    15781 tttatttata tgattttata gaattagctt ttttcttggt aaataaaata tatgaattta
    15841 tttatgcaaa aagtaaattt tattggacaa ttctatgaga atttttccta tatttcttat
    15901 aaaatataga atatataaaa ataaattaaa ttcataataa ataattttat aaaatagttg
    15961 ttaaacataa aaaaccattt gtaaaaaaca aaaaaatcat ttctctaaca aaaaaaacca
    16021 caaaaaatat aaaaaagtat ggctagttaa gtgattaaca agtaaaaatt aaaataaaaa
    16081 tcaaaaaaaa tttatcaatg aaagtcagct aaaatcctgg aagagagcat tatttttggg
    16141 aaaacatttt cttttgtttc acaaaaaaag ccactttttg gcacacaaca tgctttatat
    16201 aaagtcaaga aaaactaagg tataagacaa aggcaattag gaggtgtaaa tatggagttt
    16261 ataaattttg taagtgataa agttatagac cttaaaatgg attgtaaaac gaaagaagat
    16321 ttctttaaag aaatacataa taaagttttt gatttaggct ttgtaaaaga agaatttgga
    16381 gaaaaaatat tagcaagaga aaatgtattt ccaacaggtt taaatttagg agattatgga
    16441 gtagcaatac cacatacaga tgcagaatat attaaagagc aatttatatc agtctgtact
    16501 tttaatgaac cagtagtgtt tagttctatg gaagaccaag atgaaaaagt acctgtaaat
    16561 ttggctttcg tattaggact taatcaacca cacagtcaat tatctgtatt aacagaatta
    16621 atgggaatta tgcaaaataa agagttagtt gataagttga tgagttctac tgataaagaa
    16681 gaagttttaa agacactaaa gtctttataa aaataaaaaa gtactaaaaa taaaaaatat
    16741 aaaaataaaa attattagga ggaaataaaa atgaaaaaaa tattagtagc atgtggagca
    16801 ggaatagcaa catcaacagt agtttgtgac aaggtagaga gattagttaa ggaaaataat
    16861 atacaagcag aagttataca atgcaaaata gctgaatgtg caacaaagca agaaggagca
    16921 gatttaatag tatcaacaac tatactacca acaacttata atataccagc aataaaagca
    16981 acagcatata taactggagt aaatacagca gcattagata aaaaaatatt agatgcttta
    17041 aaataatcct atcatagata cattgaaata atattttata aaacagaaaa aggaggattt
    17101 ataaatggat aaattattag cagtagtaca atacatttta aatatgggac cgacagtaat
    17161 actaccaata acaattgtag tactaggaat gatatttaga attaagttta caaaagcttt
    17221 aaagtcaggt cttacaattg gtataggatt tgtgggtata aacttagttg taaacctatt
    17281 aacatcaaca ctagggccag cggctcaagg aatggttgaa agattcggac ttaatttaac
    17341 agtaatagat gttggttggc caacaacagc atcagcaaca tgggcttcac cagttgcacc
    17401 aatattaata ccagtttgtt tattagtaaa cttactatta ttatacttca ataaaacaaa
    17461 gatattaaac gttgatatat ggaattattg gcactttata gtagcaggtg cagttggata
    17521 tatagtaaca ggaagttatg tttgggctat attctgtgca atactaatgg agttattagt
    17581 actgtttatt gcagaaaaga cagcaaaaaa tgttcaggag ttttatgatt tagaaggtat
    17641 agcattacca actggttcaa cagcttcatt tgctccactt ggatatttag taggtaaatt
    17701 tgttgaaaaa ataccaggaa taaataaaat acaagcagac ccagactcta tacaaaaaag
    17761 atttggtata tttggagaac caatgatgat ggggattata ctaggtataa tacttggagc
    17821 acttgcggga tatgatgtag caggaatatt caatgtaggt atatcaatgg gtgcagtaat
    17881 gttacttatg cctagaatgg ttagaatatt aatggaaggt ttaattccaa tttcagaatc
    17941 aataagagat ttcttacaag caaaatatgg agacagagaa ctttatatag gtctggatgc
    18001 agcagtagca actggacatc cagcagttat atcaacagct cttatacttg ttcctataac
    18061 tttgttctta gcagttatac taccaggaaa caaagtttta ccatttggag acttagcgac
    18121 aataccattt tatatggcat ttatagtgtg ttttagaaaa ggtaatatag ttcaatcagt
    18181 tataacagga acaatagtaa tagctatatc actttatatg gctacaaact ttgcagatgt
    18241 tcatacacaa ttattacaac aagcaaatat gatgccagaa ggaacaacaa tggttacaag
    18301 tatagataca ggtggaaact tgctaaaatg gggaatattg aaattatctc aattagtttc
    18361 ttcatttgga atattctagt atgtagttaa tagagattac tcttttttag taaagtatgc
    18421 gaaaatttaa catttagcag ctactaaaaa agagtaatat tttttataaa tttttaaaaa
    18481 tacaaaatac aagaggagga gatttatcgt gaaagcagca gtattacatg gcacaaatga
    18541 tatgagattt gaagatatag aaataaaacc atgtgaaagt gatgaagtaa aaataaaagt
    18601 tatggcagca ggaatatgtg ggtcagatcc tccaagagta ttaaaacatt ggaaatatcc
    18661 agttccagct ataccaggac atgagttttc tggagtaatt gctgaagttg gtaaggatgt
    18721 aaaaaatgta aaagttggag atagagtagt tgcaattcct tttatacctt gtaatgaatg
    18781 tgaatattgt aaaagaggat tattttcatt gtgtgatgac catggaatgt taggagctaa
    18841 aagttttgga gcttttgcag agtatgtaaa tataaaagct acaaatgtac ttccaatagg
    18901 agatatgaac tttgaagatg ctgcaatgat agagccacta gcagttgcta tgcatggagt
    18961 acttaatata ggtgttcaag ttggagacac tgtagctgta atgggtagtg gaacaatggg
    19021 gcagttggta atacaaggac ttaaaatagc aggggcagga acaattatag cagttgatat
    19081 atctgataat aaattaagag aatcaaagga attaggggct gatataataa ttaatgctaa
    19141 agatattaac ccagtagaaa aaataaaaga acttactggt ggaaaaggtg ttgacatagc
    19201 tcttgaatgt gcaggttcaa aaataactca agaacaatgt ttacttataa ctaaaaagaa
    19261 aagtaagata ggatttttag ggatagcata ttcagatata actttatcag aagaagcatt
    19321 tgaaaatata tttagaaaag aactagaatt aaaaggtttt tggaactctt attctgcacc
    19381 atttccagga caagaatgga ctaagggaat caatctagtt aatgaaggaa agataaaatt
    19441 aaaagaaatg gtatctcata gattctcact tgaagatact tacaaagcat ttgaaatgat
    19501 aagagataga aaagaagaat ttaacaaaat attaatttta ccacaagggg ttgaaaaata
    19561 atgaaagcag tagttaaaac taaaccaggc tatgataatg tagaagtttt agaagtagaa
    19621 gaaccaaaag ctacaggaga caaggttaaa ataaaagtag aatatagtgg tatatgtggt
    19681 tcagatatac attcatttaa aggtgaatat gcaaatataa aagccccagt aacattaggt
    19741 catgaatttt ctggaattgt tgtagaagta ggagaagatg ttaaaaatat aaaagtaggg
    19801 gatagagtta catcagagac tacttttgca acttgtgaga aatgtatata ttgtgaaact
    19861 aaagattata acttatgccc aactagaaaa ggtattggta ctcaagtaaa tggaagtttt
    19921 gctgagtatg tattatcaag agaagaaagc atacatgtac ttcctgaaaa tgtatcttta
    19981 ttatcagcag cccttacaga gccactagct tgttgtgttc atgcagctct tgaaaagact
    20041 actatagaaa gttctgatac agttttaata ataggaccag gaccaattgg tttattatta
    20101 gctcaagttg ttaaatctca aggtgctaca gttataatgt ctggtgttac aaaagataag
    20161 gaaagattag aaatagctaa aaatcttgga gtagatagaa ctgtaaatgt aatggaagaa
    20221 agtttggcag atgtagtgaa tgaaatgact gatggaaatg gagtaaacaa aggatttgat
    20281 tgttctgggt ttatgccagc agttaacgaa gccttaagac tgcttagaaa aaaaggtact
    20341 ttcgtacaag ttggaatctt tgctaaaaaa ttaaatgaaa tggaccaaga agcaataatc
    20401 caaagagagt tacaatatat aggaagcagg tctcaaaagc caagttcttg gattacagca
    20461 ttagatttaa tggcaaatgg gaaagtaaat acagaagctt tagttactag aactgttggt
    20521 ttagacgaat ttaaagaagg tattacagct ttaatgaacg gggaagaaat aaaagtagca
    20581 gtaaaatctt aaaaaaacat ttgtattatt ttaaaaaaaa ttgtaaaatc tactgtagga
    20641 taaaaaaatg taaggtctta aaaaataaca ggaggaagaa agtatgagca ctcttagaga
    20701 tcattctaat aatattagaa aaaacataat aaaaatggtt gcagaagcta aaagcggaca
    20761 tccaggtggt tcattatcaa tagctgatat gttgacagta ttatattttg ataagatgaa
    20821 cgtatgtgca gaaaatccaa aaatggctga tagagataga tttgttctat caaaaggtca
    20881 tgcagcacca gctttatatg ctacattagc agaaaaagga tttttcccag aagaagaatt
    20941 aataacacta agaaaatttg gttctaagtt acaaggtcac ccagacatga aaaaagtagc
    21001 aggaatcgat atgtctactg gttctcttgg tcaagggcta tctgcagcaa atggtatggc
    21061 acttgcagga aaattagata acaaagacta tacagtatat actatattag gtgatggaga
    21121 aatccaagaa ggtcaaatat gggaagctgc aatgacagca tcacattaca aattagataa
    21181 tttaattgca tttgttgact taaatggatt acaaatagat ggttctaatg aagaagtaat
    21241 gaatgtaagt ccagtagatg acaaattcaa atcttttgga tggaatgtaa tagtaataaa
    21301 tggacattct tttgaagaaa taggaaatgc agttgatgaa gctaaaaaag ttacaggaaa
    21361 accaactgta ataatagcta aaacagtaaa aggtaaaggt gtttcattta tggaaaataa
    21421 tgctgcatgg catggaacag ctccaaatgc agaacaagca gagcaagcat tgaaagattt
    21481 agaaggaggt ctataggaat gggaatagca actagagaag cttacggaca agtgttaaaa
    21541 gaacttgcag aaaataaaga tatagtagta ttagatgcag atttaggaaa agctacaaaa
    21601 agtatatcat ttaaagaagt tgccccagat agattttttg acatggggat agcagaaggt
    21661 gacatgattg gtacagcagc aggtcttgct acttgtggaa aaataccttt tgcgagtact
    21721 tttgcaatat ttgcagcagg aagaggctat gagcaaataa gaaactctgt agcatatcca
    21781 aatttaaatg taaaaatagc agctactcat gcaggtgtaa cagtaggtga agatggtggt
    21841 agccatcaag ctatagagga tatatctcta atgagaggta taccaaatat ggttgtatta
    21901 aatccagcag atgctttaga agcaagacaa gctattctta catctattga ttataatgga
    21961 cctgtttata taagattagg tagagctgca actcctgatg taaacagtga aaattataaa
    22021 tttgaaatag gaaaaggaac tgttttaaga gaaggttctg acataacagt aatagctaca
    22081 ggaataatgg tagcaaaagc cttagaagca gcagaagaac ttgctaaaga aggtataaat
    22141 gtagaagttg ttaatatatc tacaataaaa ccattagatg aagcattaat aaaagaaact
    22201 gctaagaaaa ctggaaaagt agttacagca gaggagcaca gtataatagg tggtttaggt
    22261 tcagctgtat gtgaagcttt agcagaaact aaagatgtag tagttagaag aattggtgtt
    22321 aaagatgtat ttggtcaatc aggtacacca gctgatttat taaaacacta tggtttaact
    22381 ac
//
LOCUS       DAGQVA010000065        22154 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.065, whole genome shotgun sequence.
ACCESSION   DAGQVA010000065 DAGQVA010000000
VERSION     DAGQVA010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22154
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.065"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..174
                     /gene="tuf"
                     /locus_tag="MIV85_002756"
     CDS             <1..174
                     /gene="tuf"
                     /locus_tag="MIV85_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005791980.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBY2962085.1"
                     /translation="VTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGG
                     RTVASGVVATIIE"
     gene            546..857
                     /gene="rpsJ"
                     /locus_tag="MIV85_002757"
     CDS             546..857
                     /gene="rpsJ"
                     /locus_tag="MIV85_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBY2962086.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            949..1578
                     /gene="rplC"
                     /locus_tag="MIV85_002758"
     CDS             949..1578
                     /gene="rplC"
                     /locus_tag="MIV85_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBY2962087.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1608..2231
                     /gene="rplD"
                     /locus_tag="MIV85_002759"
     CDS             1608..2231
                     /gene="rplD"
                     /locus_tag="MIV85_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBY2962088.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2231..2521
                     /gene="rplW"
                     /locus_tag="MIV85_002760"
     CDS             2231..2521
                     /gene="rplW"
                     /locus_tag="MIV85_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBY2962089.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2551..3381
                     /gene="rplB"
                     /locus_tag="MIV85_002761"
     CDS             2551..3381
                     /gene="rplB"
                     /locus_tag="MIV85_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBY2962090.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3416..3697
                     /gene="rpsS"
                     /locus_tag="MIV85_002762"
     CDS             3416..3697
                     /gene="rpsS"
                     /locus_tag="MIV85_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBY2962091.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3729..4064
                     /gene="rplV"
                     /locus_tag="MIV85_002763"
     CDS             3729..4064
                     /gene="rplV"
                     /locus_tag="MIV85_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBY2962092.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4087..4902
                     /gene="rpsC"
                     /locus_tag="MIV85_002764"
     CDS             4087..4902
                     /gene="rpsC"
                     /locus_tag="MIV85_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBY2962093.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4938..5369
                     /gene="rplP"
                     /locus_tag="MIV85_002765"
     CDS             4938..5369
                     /gene="rplP"
                     /locus_tag="MIV85_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBY2962094.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5371..5574
                     /gene="rpmC"
                     /locus_tag="MIV85_002766"
     CDS             5371..5574
                     /gene="rpmC"
                     /locus_tag="MIV85_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBY2962095.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5598..5852
                     /gene="rpsQ"
                     /locus_tag="MIV85_002767"
     CDS             5598..5852
                     /gene="rpsQ"
                     /locus_tag="MIV85_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBY2962096.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5878..6246
                     /gene="rplN"
                     /locus_tag="MIV85_002768"
     CDS             5878..6246
                     /gene="rplN"
                     /locus_tag="MIV85_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBY2962097.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6270..6575
                     /gene="rplX"
                     /locus_tag="MIV85_002769"
     CDS             6270..6575
                     /gene="rplX"
                     /locus_tag="MIV85_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBY2962098.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6605..7147
                     /gene="rplE"
                     /locus_tag="MIV85_002770"
     CDS             6605..7147
                     /gene="rplE"
                     /locus_tag="MIV85_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBY2962099.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7165..7350
                     /locus_tag="MIV85_002771"
     CDS             7165..7350
                     /locus_tag="MIV85_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBY2962100.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7383..7781
                     /gene="rpsH"
                     /locus_tag="MIV85_002772"
     CDS             7383..7781
                     /gene="rpsH"
                     /locus_tag="MIV85_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBY2962101.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7812..8354
                     /gene="rplF"
                     /locus_tag="MIV85_002773"
     CDS             7812..8354
                     /gene="rplF"
                     /locus_tag="MIV85_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBY2962102.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8390..8758
                     /gene="rplR"
                     /locus_tag="MIV85_002774"
     CDS             8390..8758
                     /gene="rplR"
                     /locus_tag="MIV85_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBY2962103.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8779..9288
                     /gene="rpsE"
                     /locus_tag="MIV85_002775"
     CDS             8779..9288
                     /gene="rpsE"
                     /locus_tag="MIV85_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBY2962104.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9303..9488
                     /gene="rpmD"
                     /locus_tag="MIV85_002776"
     CDS             9303..9488
                     /gene="rpmD"
                     /locus_tag="MIV85_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBY2962105.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9521..9964
                     /gene="rplO"
                     /locus_tag="MIV85_002777"
     CDS             9521..9964
                     /gene="rplO"
                     /locus_tag="MIV85_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBY2962106.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10008..11276
                     /gene="secY"
                     /locus_tag="MIV85_002778"
     CDS             10008..11276
                     /gene="secY"
                     /locus_tag="MIV85_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBY2962107.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11293..11943
                     /locus_tag="MIV85_002779"
     CDS             11293..11943
                     /locus_tag="MIV85_002779"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBY2962108.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11944..12690
                     /gene="map"
                     /locus_tag="MIV85_002780"
     CDS             11944..12690
                     /gene="map"
                     /locus_tag="MIV85_002780"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBY2962109.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12712..12981
                     /locus_tag="MIV85_002781"
     CDS             12712..12981
                     /locus_tag="MIV85_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBY2962110.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13019..13237
                     /gene="infA"
                     /locus_tag="MIV85_002782"
     CDS             13019..13237
                     /gene="infA"
                     /locus_tag="MIV85_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBY2962111.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13273..13386
                     /gene="rpmJ"
                     /locus_tag="MIV85_002783"
     CDS             13273..13386
                     /gene="rpmJ"
                     /locus_tag="MIV85_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBY2962112.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13539..13910
                     /gene="rpsM"
                     /locus_tag="MIV85_002784"
     CDS             13539..13910
                     /gene="rpsM"
                     /locus_tag="MIV85_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBY2962113.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13946..14344
                     /gene="rpsK"
                     /locus_tag="MIV85_002785"
     CDS             13946..14344
                     /gene="rpsK"
                     /locus_tag="MIV85_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBY2962114.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14376..14999
                     /gene="rpsD"
                     /locus_tag="MIV85_002786"
     CDS             14376..14999
                     /gene="rpsD"
                     /locus_tag="MIV85_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBY2962115.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15077..16024
                     /locus_tag="MIV85_002787"
     CDS             15077..16024
                     /locus_tag="MIV85_002787"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBY2962116.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16045..16386
                     /gene="rplQ"
                     /locus_tag="MIV85_002788"
     CDS             16045..16386
                     /gene="rplQ"
                     /locus_tag="MIV85_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBY2962117.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16506..17339
                     /locus_tag="MIV85_002789"
     CDS             16506..17339
                     /locus_tag="MIV85_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBY2962118.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDDLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDGMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17327..18193
                     /locus_tag="MIV85_002790"
     CDS             17327..18193
                     /locus_tag="MIV85_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBY2962119.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18187..18990
                     /locus_tag="MIV85_002791"
     CDS             18187..18990
                     /locus_tag="MIV85_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBY2962120.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19022..19753
                     /gene="truA"
                     /locus_tag="MIV85_002792"
     CDS             19022..19753
                     /gene="truA"
                     /locus_tag="MIV85_002792"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBY2962121.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19873..20304
                     /gene="rplM"
                     /locus_tag="MIV85_002793"
     CDS             19873..20304
                     /gene="rplM"
                     /locus_tag="MIV85_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBY2962122.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20333..20725
                     /gene="rpsI"
                     /locus_tag="MIV85_002794"
     CDS             20333..20725
                     /gene="rpsI"
                     /locus_tag="MIV85_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBY2962123.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21184..21936
                     /gene="cwlD"
                     /locus_tag="MIV85_002795"
     CDS             21184..21936
                     /gene="cwlD"
                     /locus_tag="MIV85_002795"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBY2962124.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8897 a         2587 c         4551 g         6119 t
ORIGIN      
        1 gtaacaggag cttgtaagtt accagaagga atagagatgg taatgcctgg agataacgta
       61 acaatggaag tagacttaat aaactcaata gttgtagaag agggattaag attctcaata
      121 agagaaggtg gaagaacagt agcttcagga gttgttgcta caataataga gtaatccttt
      181 actaaactaa tggatttaat ataaaaaaaa gagggggtaa ctcctctctt ttttgttttt
      241 tgttgacaag tagcgctaaa gcatatatac taaactagtg ccttgagaca gattaacaat
      301 caagtttaag gttatgatgt tgtaatagaa aataaaattg aaaaaaacag aaaaaaaact
      361 tgaaaaaatg taacagatga tataaaatat aatagtgtgc ttgagagatt aagaaaataa
      421 taattaaatc ctagtgaaat acgaactgat atcgatttaa aagttacaac acacccggag
      481 cagtgtatcg gtattggttg tacgcaactt gaaaattaaa cacgtgataa aggagggaaa
      541 acaaaatggc taagaatgaa aaaataagaa taagattaaa atcatatgat cacaaattat
      601 tagatttttc agcaggtaaa atagttgaaa ctgctaaaaa ggctggatca caagtttcag
      661 gacctgtgcc tctaccaaca gaaaaacaag ttgtaactat attaagagct gtacataagt
      721 acaaagactc tagagaacaa tttgaaataa gaactcataa aagactaatc gacatagcta
      781 atccaacacc taagacagtt gactcattaa tgagattaga cttaccagca ggtgtagata
      841 tagaaataaa attataagaa cccctaagat attatcctat agatgattat cttagaatga
      901 ttactctaaa agatgtaatc cgctgtaaga attataggag gtgctaatat gaaaggaata
      961 ttaggcaaaa aagttggtat gactcaaata ttcactgata aaggtgtagt tatacctgta
     1021 acagctgttg aagcagggcc tatggtcgtt actcaaataa aaacagttga taaagatgga
     1081 tacaatgcta tacaaatagg ttttgaagat gctaaagaaa aagctttaaa caaacctaaa
     1141 aaaggacatt tagctgctgc taatgtttta aagaaacatt taaaagaatt tagagtagat
     1201 tctgtagaag gatacacagt aggacaagaa ataaaagctg atgtatttga agcaggtgca
     1261 aaaatagatg ttactggaat aagtaaaggt aagggattcc aaggtccaat aaaaagacat
     1321 ggacaaagta gaggtcctga aactcacggt tctagatacc acagaagacc aggttcaatg
     1381 ggagcttgtt cttacccagg tagagtattt aaaaacaaaa aattagctgg acatatggga
     1441 agcgtaaagg taacagttca aaacttagag gttgttaaag tagatgctga caagaacctt
     1501 atattagtta aaggagctat accaggagct aaaggttcag tagtaactat aaaagaagct
     1561 ataaaggttt ctaaataatg actaacctag agaaaggagg aataacaatg ccaaaattaa
     1621 atgtactaaa tgttagtgga caaaacgttg gagaaataga attatcagat tctatatttg
     1681 gcgtagaagt taatggacat gttttatacg aagttgtaaa aaatcaatta gcaaataaga
     1741 gacaaggaac tcaatctgct aaaactagag cagaagttag aggtggcgga agaaaacctt
     1801 ggaaacaaaa aggaacaggt agagcaagac aaggttctac aagatctgta caatgggtag
     1861 gtggaggagt tgcttttgca cctaaaccaa gaagctacaa atatacatta cctaagaagg
     1921 taagaagatt agctatgaag agtgctttat cttcaaaagt tcaaaatagt gaagttatag
     1981 tattagatgc attaaacatg gatgctccta agactaaaga atttgctcaa atattaaaca
     2041 atataaatgc tgctaaaaaa gctttagtag ttatagctga caaaaacgat aacgtaataa
     2101 aatcagctag aaatatagaa ggtgttcaaa ctgcattagt taatactatg aatgtatatg
     2161 atatattaaa atacgattca tttataataa ctacagatgc tgttaaaaaa gtggaggagg
     2221 tgtacgcata atgactaatc cacatgatgt aataataaga ccagttgtaa ctgagcacag
     2281 tatggctgaa atgggtgaaa aaaaatacac ttttgttgtg gctaaagatg cgaacaaaac
     2341 tgaaataaaa aaagcagtag aaaaagtatt cggagttagt gttgataaag taaatacttt
     2401 aaactacgat ggaaaagtta aaagaatggg tagaactcaa ggaagaacat caagctttaa
     2461 gaaagcagta gttaaattaa ctgctgatag taaagaaata gaattcttcc aaggaatgta
     2521 gtattataac aaacgaagga gggaaaacag atggctataa aaaagtttag accaacttct
     2581 cctgccttaa gacaaatgac agttttagtt tctgatgaaa taacatgtaa tcaaccagaa
     2641 aaatctcttt tagttaactt aaagaaaaat gctggtagaa acgtacatgg tagaataact
     2701 gttcgtcata gaggtggagg acaaaaaaga aaatatagaa taatagattt taaaagagat
     2761 aaagatggta tacctgctaa ggttgctact atagaatatg atccaaacag aactgcaaat
     2821 atcgcattat taaactatgc tgatggagaa aaaagatata tattagctcc agttggaatt
     2881 aacgttggag atactatatt atcaggatta ggtgctgata taaaaccagg aaactgttta
     2941 gcattaaaag atatgccagt tggtactatc attcataata tagaattaaa gccaggaaaa
     3001 ggagctcaat tagttagatc tgctggagtt tctgcacaat taatggctaa agaaggaaaa
     3061 aatgctttat taagattacc atcaggtgag atgagattag taagcataaa ctgtaaagct
     3121 actataggtc aagttggaaa tatagagcat ggtaacgtag ttatcggtaa agcaggtaga
     3181 aaaagacata tgggaataag acctactgta agaggttctg taatgaaccc taatgaccat
     3241 ccacacggtg gaggggaagg tagatctcca ataggtagac catctcctgt tactccatgg
     3301 ggtaaaccag ctcttggata caaaactaga aagaaaaata aagcttcaaa taaactaata
     3361 gtatcaagaa gaactaagta gtaaatttat ttttgctcgg aaaggaggaa tataaatgtc
     3421 aagatcaact aaaaaagggc cttttgtcca tgcaagactt ttaaagaaga tagaagctat
     3481 gaatgctagt ggaaataaag aagttataaa aacttggtca agatcttcaa ctgtatttcc
     3541 acaaatggta gaaaacacta tagctgttca tgatggaaga aaacatgttc cagtatatat
     3601 aacagaagat atggttggac ataaattagg tgagttcgtt cctactagaa ctttcaaagg
     3661 acataaggat gacgaaaaat ctaataagag aaaataatta aattatgact aagaaaggag
     3721 gaataacaat ggaagcaaaa gctactgcta aatacgtacg tgtatcacca agaaaagcag
     3781 gccaaatatg tgaccttgtt agaggaaaga atgttgatga agcattagca atattaaagt
     3841 ttactccaag aggagcagct tcaataatag ctaaggttgt aaaatcagct aaagctaacg
     3901 cagaaaacaa tcacgaaatg gatactgaaa aattatatat agcatcaata gttgctaatc
     3961 aaggaccaac aatgaagaga ttcatgccta gagctatggg tcgtgcaact acaataagaa
     4021 aaagaacttc tcatatagag gttgttgtta aagaaaaaaa ataattaata gataggaggg
     4081 aaagtaatgg gtcaaaaggt taatccacac ggcttaaggg tcggtgttat aaaagattgg
     4141 gactcaagat ggttcgctac tgataaaaaa gagttcggaa acttattatt agaagaccat
     4201 aatatacgta aattcttaaa gaaaagatta tactcagctg gagttgctaa gatagaaata
     4261 gaaagatcag ctaacaaaat aaaaatggac ttacacgttg ctaagcctgg tgtagttata
     4321 ggaagagctg gtgcaggaat cgaagcatta aaagctgaat tagaaaaaat gacaaagaaa
     4381 actataatag ttaatatagt agaagtaaga agtacagata aaaatgctca attagtagct
     4441 gaaaatatag ctttagctat agagagaagg gttgctttca gaagagcaat gaaacaagct
     4501 atacaaagag caatgaaatc tggtgctaaa gggataaaag tttctgcttc aggaagatta
     4561 ggtggagctg aaatggctag aactgaaggt tatagtgaag gaaatgtgcc actacaaact
     4621 ttaagagcag atatagatta tggtttcgct gaagctgata caacttatgg aaaaatcggt
     4681 ataaaagttt ggatatgtaa tggtgaagtt ttaccaacta gagacggtgt aaatccaaga
     4741 gaagaaagca gaaagagcga tagaagagac aacaagagag ataatagaag aaacgataga
     4801 agaggaaatg acagaagagg aaatgataac agaggaaact acagaggaca aagacctcaa
     4861 ggtggatcaa gacctcaaag aactgaaaac aaaggaaatt aataatagtt aggttcaagg
     4921 aaggaggaaa aatactcatg ttaatgccaa aaagagtaaa gcgtcgtaga gttcatagag
     4981 gaagcatggc tgggcaagct cataagggta ataaagttac ttatggtgag tttggattag
     5041 tagcattaga agcttcttgg ataacttcta atcaaataga agctgccaga atcgcgatga
     5101 ctagatatat aaaaagaggg ggaaaggttt ggataaaaat attccctcat aaaccagtaa
     5161 caagaaaacc agcagagact cgtatgggtg cagggaaagg ttctccagaa tattgggtag
     5221 ctgtagttaa gccaggaaga gttatgtttg aattagcagg tgtttctgaa gataaagcaa
     5281 gagaagctat gagacttgct gcacataaat taccaatcaa atgtaaattt gttaaaaaag
     5341 aagatttaga agtaaagggt ggtgaatagg atgaaagcta aagaattaag agatttaaca
     5401 agcgaagagc taatgaacaa attaaacgac ttcaaaagtg aattatttag cttaagattc
     5461 caattagcta ctggtcaatt agaaaataca gctagaataa agtttgttaa gaaggatata
     5521 gcaaaagtta aaactgttct tgctgaaaga aagttatacg aaactagagc ttaatttgga
     5581 aaggaggctt tttaaacatg gaaagaggaa gaagaaaagt tagaataggc cgtgttgtta
     5641 gtgataagat ggataaaaca atagtagtag ctgttgaaga attcgtacgt catccactat
     5701 ataataaacg tgttaagaga actaagaaat tcaaggctca tgatgaaaag aatatatgta
     5761 acatcggaga tagagttaaa ataatggaaa ctagaccatt atctaaagat aagagattca
     5821 gactagttga agttgttgag aaagttaagt agtttttgaa gaaggaggga ttacgatatg
     5881 atacaacaag aatcacgtct aagagttgct gataactcag gagctaaaga acttttatgt
     5941 atacgtgttc taggcggaag taaaagaaga tatggtaaca taggcgacgt tatagttgct
     6001 actgttaaaa gtgcaacacc tggtggagtt gtaaaaaaag gtaaggttgt taaagctgtt
     6061 atagtaagaa gcaaacaagg cgtaagacgt aatgacggaa gctatatatc ttttgatgaa
     6121 aatgctgctg ttataataaa ggacgataaa actccagtag gaactcgtat attcgggcct
     6181 gttgctagag agttaagaga caatgaattc atgaaaatag tttctcttgc tccagaagta
     6241 ctataattaa ggaggtgcaa taggacatga tgcgtgttaa aaaaggtgac actgttgtag
     6301 ttatagcagg taaagataaa ggtaaaaaag gttcagtttt aaaggtatat cctaaaacta
     6361 gcaaagtgtt agttgaaggt gtaaatgtaa taactaaaca tcaaaaacca agtgctatga
     6421 accaacaagg tggaataata aataaagaag ccccaataca catatctaat gtaatgccat
     6481 ttgatcctga aacaggaaaa ggcgttagag taagatatga agtaaaagat gggaacaaag
     6541 taagagtatc agcaaagagc ggaaaagaat tataataaat attgcttgaa aggagggacc
     6601 ttaaatggct tctagattac aagaaaaata catgaaagaa gttgctcctg ctttaatgga
     6661 gaaatttgga tacaaaaacg taatggagat acctaagtta aataaaatag ttattaacat
     6721 gggtataggt gacgctagag aaaatccaaa aggattagaa aaaggcgttg aagaattaga
     6781 aatgatatca ggacaaaagc ctgttataac taaagctaga aaatctgttg ctaacttcaa
     6841 attaagagaa ggaatgccaa taggaacaaa agttacatta agagctgaca aaatgttcta
     6901 ctttatggac aaattagttt cagtttcttt accaagagtt agagacttta gaggagttaa
     6961 ccctaatgct tttgatggta gaggaaatta tgctttagga gttaaagaac aattaatatt
     7021 ccctgaaata gaatatgata aaatagataa agtaagagga atggatataa tatttgttac
     7081 tacagcaaaa actgacgaag aagctcgtga attattaaaa ttattaggaa tgccattttc
     7141 taagtaagca aaggagggat tcccgtggct agaaaagcga tggttgttaa gcaacaaaga
     7201 aagcaaaagt acgctactag agaatacact agatgtacta tatgcggaag accgcattca
     7261 gttttgaaaa aatttggtat atgccgtata tgctttagag aattagctta taaaggtcaa
     7321 atacctggtg ttagaaaagc aagctggtag aagcttgatt agaatggaag gagggcaaca
     7381 aaatgacaat gacagatcca attgcagata tgcttactcg tataagaaat gctaatgttg
     7441 ttaagcatga aactgtagat gttccagctt ctaatatgaa gaaagaatta gctagaatct
     7501 tattagaaga aggtttcata agaggttatg atgttataga agatggaaaa caaggtatca
     7561 taagaataca attaaagtac ggacaagaag gcgaaagagt tataacaggt cttaagaaaa
     7621 tatctaagcc tggaatgaga gtttacgctg ctaaccatga gataccaaaa gtattaaacg
     7681 gattaggaat atcagttata tctacttcaa aaggaatatt aactgacaag caagctagaa
     7741 aagaaaatgt tggtggagaa gtaatctgct acgtttggta attaatatga acaatgtaag
     7801 gaggtgcgac catgtcaaga ataggtgtta agccaataat aataccagca ggtgttgaag
     7861 ttactatagc tgaaggaaat ttagttacag taaaaggtcc aaaaggaact ttaactaaac
     7921 aattaagtgc tgagttaaac ataaaaaaag aagaaaatac aataatggtt gaaagaccaa
     7981 ctgataataa aaaacataga tctttacacg gactaactag aactttatta gataatatgg
     8041 ttgtaggtgt aaatactggt ttcgaaaaga aattagaatt aaaaggtgtt ggatatagag
     8101 ctcaaaaaca aggaaagaaa ttagttatga acttaggttt ctctcatcca gttgagatgg
     8161 aagatccaga aggaataact gttgaagctc caaaccaaac agagttaata gtaaaaggta
     8221 tagacaagca attagtaggg aattatgctg ctaagataag agcttggaga aagccagagc
     8281 catacaaagg taaaggtata aaatacgttg atgaagtaat cagacgtaaa gaaggaaaaa
     8341 ctggtaaaaa ataataccaa aacttaaacg ctagaaagga gtgagctagg tgttaaaaaa
     8401 ggctgataaa aatgctaata gacttcaaag acataagaga gttcgtagaa aaataagcgg
     8461 tacttctcaa agaccaagat tatgtgtatt tagaagtgct aacaatatat atgctcaaat
     8521 aatagatgac acaaaaagag taactctagt tgctgcatct tctttagaag cagaagttaa
     8581 gagtgctgtc aatcatacag gaaacaagga agcagctaag aaagttggag aattagttgc
     8641 taaaaaagct gttgaaaaag gaatcactga agttgtattt gacagaggtg gatacttata
     8701 tcatggaaga attcaagaat tagctgaagg tgctagagaa gctggtctta agttctaata
     8761 cgaaggaggg aaaaatacat gctacgtcgt aagccgatag atgcaggaca acttgactta
     8821 caagaaaaag ttgttgaagt aagacgtgtt actaaggttg taaaaggtgg tagaaatttc
     8881 agatttgcag cattagtagt tgttggagat gaaaacggac acgttggtat aggtgctggg
     8941 aaagcaatgg aagtaccaga cgctataaaa aaagcagttg aagatgctaa gaaaaatcta
     9001 atagtagtgc caatagttgg gactacaatt cctcacgaag tacgcggaca ctttggtgct
     9061 ggaaatatat taataatgcc tgctgtagaa ggtacaggag taatagctgg gggacctgct
     9121 agagccgtac ttgagctagc tggactaaaa gacgttagag ctaaatcttt agggtctaac
     9181 aatccaagaa atatggtaaa tgctacaata gaaggactta attctctaaa aacagttgaa
     9241 gatatagcta aacttagagg taaaaaagtt gaagaacttc tagggtaagg aggtagtgta
     9301 aaatggctaa attacaaata aagttagtta gaagtgttat aggaactact cctaaccaaa
     9361 aaaagaatgt tgaagcgtta ggattaagaa aaagagaaca agttgttgta aaagaagaca
     9421 atgctcaaac aagaggtatg ataaataaag taagtcactt attagaagta actgaaatag
     9481 ctgaataatt tttataaagt agtgcaagga ggtgcaatcc atgaagttac atgagttaaa
     9541 acctgctgaa ggtgcagtaa gagctaagag aagattaggt agaggtactg caactggaca
     9601 aggtaaaact gcaggacgtg gacaaaaagg tcaatggtct cgttctggtg gtggagtaag
     9661 agtaggattt gaaggtggac aaatgccact agctagaaga cttcctaaga gaggtttcaa
     9721 taacatattt aagaaagttt acacagaagt taatgttgaa gttttaaaca gatttgaaaa
     9781 tggaacagaa ataactgcag aattattaaa atctactaaa actataagca aaataggtaa
     9841 agacggaatt aaaatcttag gtgaaggtaa tttagagaaa gctttaactg ttaaagctgc
     9901 taaatttaca gcttcagctc aagaaaaaat agaaaaagct ggtggaaaag cagagttagt
     9961 ataataacct gctaatctcc tagccagtac aggcggggtg aattagcgtg ctgtcaaaat
    10021 taaaacaagc ttggaagatt aaagcagtaa gaaaaaaagt aatgtataca cttatgatga
    10081 tcgtgatatt cagaataggt actactatac cagttccagg catagacact agtattatac
    10141 aaaagatggt aggcggcaat agtctacttt ctctgtataa tatgtttact ggtggagcat
    10201 ttagtaactt ttcactattt gctttaggta taagtccata tatcactgca tcaatcataa
    10261 tacaacttct aacagtaggt tttgaaagtt tagcagaact tcaaaaatct ggtgaagaag
    10321 gaaagaaaaa aatcaataag tacactaaat atacagcact agctctagca gttgtacaag
    10381 ctttgggaat tacattagga attgtaagaa gtgctttaat atcaaatagt gtgtttttta
    10441 tcacaactgt tgtaataaca ttagtttcag caagtatgtt agtaatgtgg attggggaca
    10501 aaattactga aaaaggaatc ggtaatggta gttcagtaat aatatttgca ggtataatat
    10561 caagaatacc tacagatgtt attaaaatat cgcaacaagt taaatctggc gaagttgcac
    10621 cttgggttat agtgattcta gctgtagtta tattacttac agtaacagga gttacattta
    10681 tacaagaagc aactagaaag atacctgtac aatatgctaa aagagttgtt ggaagaaaaa
    10741 tgtatggagg acaaagttct catataccaa tgaaagttaa ccagtcagga gttatgccta
    10801 taatttttgc tagttcactt ttagctttcc ctcaaacaat agctatgttt atgggtccaa
    10861 atgctcaggc ttttgttcaa aaatacttaa gtatggcaac agaacaagga ttttggacat
    10921 atagatcaat tgagattcta cttataattt tcttctcata tttttataca actgtatcat
    10981 ttaatacaga agacatatct aaaaatatga aaaataatgg tggatttata ccaggtataa
    11041 gaccaggtga gcctactatg gattatttaa atagaatttt aactagatta actttagctg
    11101 gagctacttt cttagcaata attgctatgg tgccagctct tacaacacat tatatgaaag
    11161 taaatatgag tctagctggg acttcattgc taatcgttgt tggagttgct ttggagctta
    11221 agagacagtt agagtcaaac ttagttatga gaagctatca aggtttctta aaataaaatg
    11281 gagatggata atatgagaat aatattactt ggacctccag gtgctggtaa aggtactcag
    11341 gcggcaggaa tagtagaaaa atacaatata cctcatatat caacaggaga tatattcaga
    11401 aagaatataa aagagggaac agaacttgga aaaaaagcta aagaatacat ggaccaaggt
    11461 ttattagtac cagatgagtt aactgtaggt ttagttactg atagaatatc tcaagaagat
    11521 tgtaaaaatg gatttatgtt agatggattt ccaagaaatg tagcacaagg agaacattta
    11581 gatatcttct taaaaaatgc tggtatatca ctagataaag ttgtcaatat tgaagttgat
    11641 aagagtatat tagtgtctag agcagttggt agaagaatat gtaagtcttg tggagctact
    11701 taccatgttg agtttaatcc tcctaaagta gaaggtgtat gtgatgtatg ccaaggagaa
    11761 ttatatcaaa gagctgatga taatgaagaa actgtatcta agagaataca agtttatcta
    11821 gatgaaacta agcctttagt agattattat agcaaacaag gtataatagc agatataaaa
    11881 ggtgatcaag caatagataa agtatttgaa gatattgtcg cagccttagg aagtggaaaa
    11941 taaatgatta tcttgaaatc aaaaaaagaa atagaacttt taagagaagc aggtaaaata
    12001 gttgctgaca ctcatgaagt tttaagaaaa gctatttctc cgggaatatc tactttagaa
    12061 ttagataaaa tagctgaaga gaatataaga aaatacaatg cagaaccttc ttttaaagga
    12121 tatggaggtt ttccaggaag tatatgtgct tctatcaata gagaggtagt acatggtatt
    12181 ccaggagaaa ctatattaca agaaggtgac attgtaagtt tggatatagg agcctattat
    12241 aaaggatatc atggtgattc tgcgaaaact cacggagtag gcatgatatc tgaagaagat
    12301 aggaaattga tagaagtaac tagagaaagc ttctatgaag gaataaaatt tgctaaatta
    12361 ggatatagac tttcagatat ctcacacgca gtacaaacac acgttgagaa acatggtttc
    12421 tcggtagtta gagatttagt gggtcatgga gttggagcaa atcttcatga agacccacaa
    12481 gtacctaatt atggactccc aggaaaagga ccaagactta gagaaggaat ggttattgct
    12541 atagagccaa tggttaatgc aggtcgttat catgtaaaga ctctatcaga tgggtggacg
    12601 actgttacaa tagatggaaa aaaatcagct cattatgagc atacgatagc aattactgaa
    12661 catgaacctt tgatattgac aaagttgtaa tttaaaaagt aggtgaaaaa agtgctatca
    12721 gataatttaa gtataggtca agttgttaaa gtttcattag gacgagataa aggaaattta
    12781 ttctttgtag tcaaaataat taataatgaa tatgtattaa tagctgatgg aaaaaagaga
    12841 aaacttgaca aacctaagtt aaagaaagtg aagcacttaa aaaaatataa ttttattaat
    12901 gatgaagtta gaaaaagagt agtatctgga caagagatta cagattcttt tttaagagct
    12961 gaacttacta agttaaatta gataatttaa cttattgaaa tggagggctg gttagttaat
    13021 ggccaaaaaa gatgttatag aattagaagg tacagtttca gaagctttac ctaatgctat
    13081 gttcaaagtt aaactagaaa atggacatga gatattatgc cacatttctg gaaagctaag
    13141 aatgaacttc ataagaattc ttgaaggtga caaggtgaat gttgaacttt ctccatatga
    13201 ccttacaaga ggaagaatta cttggcgtaa gaagtagact atattaatat ttagtctaag
    13261 gagggattaa taatgaaggt tagaccatca gtaaaaccaa tatgtgaaaa atgtaaagta
    13321 ataaaaagaa aaggaaaagt aatggttatc tgtgaaaatc caaagcataa gcaaaagcaa
    13381 ggataagaaa ttattactag cattttgtta aattttatag tataatacta tattgtgatg
    13441 ttaacaaaag aacgttaaaa tcgttgaaca atctggcgta ggattggcat atgatgtgaa
    13501 gttttaaaca ctaaaaacta tgtgtaggag gtgcgatcat ggcaagaata gctggggtag
    13561 atttacctag agaaaaaaga gcggagatag gcttaactta tatatatggt ataggtaaag
    13621 cgactgctaa cgaaatatta gctaaggctg agataaatcc agatactaga ataaaagatt
    13681 tatcagaaga tcaagttaat gagttaagaa aagttataga tgacgatttc ttagttgaag
    13741 gtgacttaag aagagaaatt gctttaaaca taaagagatt aagagatata aaatgttata
    13801 gaggaataag acacgctaaa ggtcttccat taagaggaca aagaactaag actaatgcta
    13861 gaactagaaa aggtcctaga aaaacagtat ctcgtaaaaa gaaaaaataa ataaataata
    13921 actagatgaa ggagggaaaa ggaaaatggc taaaccaaaa aagaaagtta cacgtattag
    13981 aagaagagaa cgtaaaaata tagaacgtgg tcatgctcat atacaatcaa ctttcaataa
    14041 tacaataata actttaactg acgttcacgg aaatgctata tcttgggcaa gttctggaca
    14101 attaggattc aaaggatcaa gaaaatcaac tccatttgca tctcaaatgg ctgctgaaac
    14161 agctgcaaaa gctgcgatgg aacacggact aaaaagtgtt gaggtattcg taaaggggcc
    14221 aggttcagga agagaagctg caataagagc tttacaagca actggactag aagtaactat
    14281 gataaaagac gttactccaa tcccacataa cggatgcaga ccaccaaaga gaagaagagt
    14341 gtaattaata agagtacaat aggaggtgta gataaatggc aagatataca ggtgcatcat
    14401 gtagacaatg ccgtagagag ggaatgaaat tattccttaa aggtgataga tgttatacag
    14461 ataaatgtgc tatagtaaaa agaaactatg ctccaggtca acatggccaa ggaagaaaga
    14521 aagtttctaa ctatggatta caattaagag aaaaacaaaa agttaaaaga atatatggag
    14581 ttttagaaac tcaatttaga aatttatatg aacgtgctga aaatatgcct ggtaaagcag
    14641 gtgagaactt attaagttta ttagagagaa gattagataa tgtagtttac agaatgggac
    14701 tagcatcttc tagaaaagaa gctagacaat tagtgactca tggtcatttc actttaaatg
    14761 gaaataaagt agacatacct tcattaatag ttaaggttgg agatgttata gaagttaaag
    14821 agaaatcaag atcttctgca aaattcaaaa atttagtaga agttaactca agaatagctc
    14881 ctaagtggtt agaagctaat gtagaaggaa tgacagcaaa agtagttggt gttccaacaa
    14941 gagaagatat agatcttgag atagcagagc acttaatcat agaactttac tctaaataat
    15001 aagcacactt ttaaaaatta ttttaaaatt ttgtttaccc tcagtggatt actgaatttt
    15061 aaggagggtt ttgtccatga tagaaataga aaagccaaaa gtagatatag ttgagcttag
    15121 cgaagactat agatatggta agtttgttat agagcctcta gaaagaggat atggaataac
    15181 tataggtaac gcattaagaa gaatattatt atcatcatta ccaggtgtag cagtgaatgc
    15241 tataaaaata gatggagttc ttcatgaatt ttcaacaata cctggtgtta aagaagatgt
    15301 tactgagata atattaactt taaaagagct ttcagcaact atagatggtg aaggaagtag
    15361 aacacttaaa atagaagctc aaggaccatg ctctatcaca ggtgcagata taatctgtcc
    15421 tccagatgtt gaaatattaa gtaaagattt agcaatagct acattagatg ataatgctaa
    15481 acttaatatg gagatatttg tagataaagg tagaggttat gtttctgctg aagaaaataa
    15541 aacagagaat gttccaatag gtgttttacc tgtggattca atatatactc ctgttgagaa
    15601 ggttagttat catgtggaaa acacaagagt tggtcaaaaa acagattatg ataaattagt
    15661 actagaagtt tggactaatg gtagtataaa tcctcaagag ggcatatcat tagctgcaaa
    15721 ggtattagtt gagcatttaa acttatttat agacttaact gaacatgtaa gtagtgttga
    15781 aatcatggta gaaaaagaag aagatcaaaa agaaaaagtt cttgaaatga ctatagaaga
    15841 attagattta tcagttagat catataactg tttaaagaga gcgggaatta atacagttga
    15901 agaattagct aataaatctg aggatgatat gatgaaggtt agaaacctag gtaagaagtc
    15961 attagaagag gtaatacaaa aactagaaga acttggattg ggattaaaac caagtgaaga
    16021 atagcgagca aaggagggat aagaatggct aagtaccgta aattaggacg tgaaacagct
    16081 cacagaaacc ttatgttaag aaacttagta acttgcttac taagaagtgg aagaatagaa
    16141 actacagtga ctagagcgaa agaaactcgt agaatggctg aaaagatgat aactcttgct
    16201 aagagagggg atcttcatgc tagaagacaa gttttagctt atgttatgga tgaaacagta
    16261 gttaataact tattcacaga tttagctcca aaatatgctg agagaaatgg tggatacact
    16321 agaataataa aaatagggcc aagaaaaggc gatgctgctg aaatggcttt tatagaatta
    16381 gtatagtaag gaaaggatta ggcttgatgg cttaatcttt tttttatttt tttgactaag
    16441 gtgtgatata ataatgtgta aaatgatttt tataagttat tgcttactaa aaggagtatg
    16501 agttaatgga taatatagta aaggtaaata atatttcgtt tgagtatatt acagatgaag
    16561 caaaacttaa agcaatagat gatttaagcc tagatgttaa aaaaggagaa tttgttgcaa
    16621 taataggaca taatggttct ggtaagtcta ctttatctaa aaacttaaat gctattctta
    16681 tgcccactga aggaaatatt cttattgatg gtatggacac taaagaagaa gaaagattat
    16741 gggatataag acaaactgca ggcatggtat ttcaaaatcc agataatcaa atagttgcta
    16801 ctatagtaga agaagacgtt gcatttggac ctgagaactt aggtatagaa ccaaaagaaa
    16861 taagacgaat tgtagaagag tctttaaaaa gtgtaggtat gtatgattta agagatagac
    16921 agcctcactt gttatcagga ggtcaaaagc aaagagttgc aatagcagga attattgcta
    16981 tgaggcctaa atgtataata tttgatgaag caacagcaat gttagatcca tctgggagaa
    17041 aagaagttat gaaaacaata aaaagactta ataaggaaga aaatataact gttatacata
    17101 taacgcactt tatggaagaa gcagtagaag ctgatagagt tgtagttatg gaaaaaggaa
    17161 agaaaatctt agagggaact cctagagaag tattcagtaa aataaagatg ttaaaggaaa
    17221 tcggtttaga tgtaccttgt atgacagagt tatctagttt attaatagaa gaaggtataa
    17281 atattagtag tgatatatta actgtggatg agatggtgat ggaattatgt caattatagt
    17341 aaagaattta acacatatat ataatgaagg gatgcctttt gcaagtaagg cacttgatga
    17401 tgtttctttt gagattaaag atagagattt tgttggtctt ataggtcata caggctcagg
    17461 aaaatctaca ttaatacaac atttaaatgg attactaaag ccttcctcag gagaaatatt
    17521 tataaatgat tttaatataa cagataaaaa cttgaattta actgagatta gaaaaagagt
    17581 aggggttgta tttcaatatc cagaatacca attgtttgaa gaaacgattg ataaagatat
    17641 agcttttgga ccctctaatt taggcttaga ggagtctgag atacataaca gggtaaaagc
    17701 atcaatggaa gctgtaggac ttgattatga gggatttaaa gacaaatctc cttttgaatt
    17761 atctggggga caaaagcgta gagtagcaat tgctggagtt atagccatga acccagaagt
    17821 tctcatattg gatgaaccaa ctgctggtct tgaccctggt ggaagagatg aaatttttaa
    17881 cttaataaaa gacttacatg aaaaaaagaa tatgactata atactatcat cacatagtat
    17941 ggatgatatg gcaaagttag caaaaacttt aattgttatg aatcatggta gcgtagaatt
    18001 tatgggaact cctagagaag tgtttaaatc aaatgctagt aaattaaaag atataggatt
    18061 agatattcca caagttttag aacttgcatt gaaattgaga gaaaaaggct ttgacatcag
    18121 tgaggatata ttgactttag aagaagcaaa acaggaaata ttaaaagttg tgagaggacg
    18181 aggattatgt taaaagatat aactataggg caatactacc caacaagttc tgctattcat
    18241 aaattagatc caaggataaa gcttgtagcg acaattgtat ttatggtatc tatatttgta
    18301 gtaaataaat tttggcctta tatagtagtt ttattatgtt tattagctat gataaaattg
    18361 gctaatatac cagtcaaata tattgttaag ggtgttaaac ctcttaaatg gattattttg
    18421 tttacatttc ttataaatat ttttttctta ccaggtgatg aaatatggtc atttggattt
    18481 ttagctatta caaaacaggg tctaagacaa gcaattttta tggcaataag attaatattt
    18541 ttagtagttg gtacatcatt gcttacttta acaacttcac caatagaatt aactgatgga
    18601 atagagagat tgttgaatcc atttaagaaa attggtttgc cagttcatga acttgcaatg
    18661 atgatgacaa ttgctttacg ttttattcct acattgttag atgagacaga caaaataatg
    18721 aaggctcaga tgtctagagg tgcagatttt gaaagtaaga atcttataaa tagagcaaag
    18781 aatttagtac cacttttggt acctttattt gtaagtgcat ttagaagagc tgatgaattg
    18841 gctatggcca tggaggccag atgttacaga ggtggacata ataggactaa gatgagagag
    18901 tctgttatat caagaaggga ttatatggca tgtgtatttc aggttgttta tctgggagca
    18961 attatagcta ctagatttat agcaatttaa ttaataagtt atagatataa tgaggtaaag
    19021 tatgagaaat ataaaaatta aaatccaata caatggtaag aattattgtg gatggcaaaa
    19081 gcaacctgat tctttaggga tacaaggtac aattgaaagg gctatatatg atataacaaa
    19141 agaagaaacc agtcttatag ggtctggtag aactgattca ggagttcatg ctattggtca
    19201 gattgcaaat tttaaaatta attcaggtat aagtatagaa agtataccaa tggcactaaa
    19261 tgccaagttg ccaaaagaca tatcagttat agaagcatgt gaagtaaatg atgattttca
    19321 ctccagatac agtgcaaaag gtaaaacata taaatattta gtatataata gcaagtttag
    19381 aaatccaata cttagtgaga tatcatatca agtaaaatat gaacttgatt ttgataaaat
    19441 gtgttcagaa gcaaaaagtt tattaggaac acatgatttt aaaggtttta tgagttctgg
    19501 ttcatctgta aaagatacag ttagaacgat atatgatatt gatataagta aaaaagatga
    19561 cttgattact tttgagatta gtggtaatgg ttttttatat aacatggtga ggattattgt
    19621 tggaacactt gttgatatgg gtcgtggcag aattaacgaa ccatttttag atataataca
    19681 atcaaaaact aggtcaagat gtggacatac agctccagca caaggattat ttctcaaaaa
    19741 agttcattat taacttgaca caccaggcta catgtattaa aatatatgag aatgtgttaa
    19801 taagtccact tgccccggac ttgacataaa cggtaaaaaa attttatgaa aagtagttaa
    19861 ggagggacag ttatgaaaag ttatatagct aagccagctg atgtacaaag aaaatggtac
    19921 ttagttgatg ctgaaggaaa aacattaggt cgtttagcaa cagaaattgc gacagtattg
    19981 agaggtaaac ataaaccaac atttactcct cacgttgatg gtggagattt tgttgttgta
    20041 gtaaatgcag aaaaaatagt tttaagtggt aagaaattag atcaaaaata ttacagatac
    20101 catactggtt atgtaggtgg attaaaagaa atatcttaca gagatatgat ggataagaaa
    20161 ccagaagaag ttatatcaca tgctgtaagc ggtatgttac ctaaaaataa attaagaagc
    20221 agaatgatga ctagattaag agtatttgca ggtgctgagc acactcatgc agctcaaaat
    20281 ccagaagttt taaactttaa ataagattaa taggtgaaag gaggagttta taatggctaa
    20341 cgttcaatat tatggaactg gaagaagaaa aagttctgtt gctagagtaa gactagttgc
    20401 aggtgaagga aatatattag taaatggaag agcattagaa aattatttta attatgagac
    20461 attaataaga gatgttaaac aaccattagt tttaactggt aatgaaaata aatatgatgt
    20521 tatagtaaaa gttgaaggtg gaggattcac tggacaagct ggagctataa gacatggaat
    20581 atctagagct ttattaaaag ctgatttaga tttaagacct gctttaaaga aagaaggttt
    20641 cttaactaga gatgcaagaa tgaaggaaag aaagaaatac ggattaaaag cagcaagaag
    20701 agctccacaa ttctcaaaaa gataattact tatttttttg gaaaagcaaa atcctttatt
    20761 tactgttatt cagaaagtat tggtatttta aaaatgttgg gttaagttaa ttattgatat
    20821 ataataaaat aataagatat cttattagga tgtttttcat taagaagaac atccttttta
    20881 ttttgactat ttaataaaaa acatatgcta ataagattta aattttattt ttataatatt
    20941 gtaatttaaa agtttatata aggttatata ttttaagata ttatttaaca atataaattc
    21001 tgaatatacg ttatcaaagt ttataatata aactaagtat aatttattgt atagtattga
    21061 atgttagata aacatagtga attaaatagg ggcagaaata taatatcatt acataataat
    21121 atattaatac caataaataa agatatatca atattaaaaa aatttaaatg tttgtactaa
    21181 tatatggaat attatagtgt ttttataagt atacatatac agggtgatgt tgtgagaaag
    21241 tacataaaac atataatttt tagttttgca atgatatgtc tagtagtagt atccatattt
    21301 gaaattaaaa atatttctga agatgttatc aagtatatgc cagtaacaaa caaaactata
    21361 attttagatg ctggtcatgg aggcattgat ccaggtgcat taaataagga taagagtaca
    21421 tctgaaaagg atattaacct agcaataaca cttaagctta gagagcttat agaatcaagt
    21481 ggtggccttg taatattaac tcgagaagat gacagtagcc tttataaaga agaaaataat
    21541 aaaactacaa gacaaaaata taatgagaat ttgaaaaata gaaaagaaat aatatctaat
    21601 tctaatgcca atatgtttgt ctctatacat cttaatgcat ttgaacaatc aaaatactat
    21661 ggagctcaaa ctttttatcc taaagacaaa caagacagta aagaattatc gaagtgtatt
    21721 caagaagaac ttaaaagagt agtagataag acaaacaaca gagaagtcaa accaagggat
    21781 gatatatatc ttttgaaaga aaataatatt ccatcagtac tgatagaatg tggtttttta
    21841 tcaaatgaaa aagagtgtaa actcttaact gatgaaacat atcaagaaaa aatagcatgg
    21901 gcaatctaca taggaataca aaaatattta agttgaaata actataaaaa taggtctaaa
    21961 tatgtaaata gcttgtatta aagcagttaa aatgcattaa tataggctat ttttattttg
    22021 acaaaaaaat atttaaaata aaagttaaaa agttgttgac ttagaataat atagatgata
    22081 ttatatatga gtgcccaaaa ggagcaccaa aataagacaa aagaactttg aaaattaaac
    22141 agtaggttaa ttta
//
LOCUS       DAGQVA010000066        21867 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.066, whole genome shotgun sequence.
ACCESSION   DAGQVA010000066 DAGQVA010000000
VERSION     DAGQVA010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.066"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..782)
                     /locus_tag="MIV85_002796"
     CDS             complement(<1..782)
                     /locus_tag="MIV85_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2962125.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANG"
     gene            1088..1534
                     /locus_tag="MIV85_002797"
     CDS             1088..1534
                     /locus_tag="MIV85_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBY2962126.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            1536..2630
                     /locus_tag="MIV85_002798"
     CDS             1536..2630
                     /locus_tag="MIV85_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBY2962127.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGIISHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADRNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            2718..3248
                     /locus_tag="MIV85_002799"
     CDS             2718..3248
                     /locus_tag="MIV85_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2962128.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(4185..5561)
                     /locus_tag="MIV85_002800"
     CDS             complement(4185..5561)
                     /locus_tag="MIV85_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962129.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILSNYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            5829..7001
                     /locus_tag="MIV85_002801"
     CDS             5829..7001
                     /locus_tag="MIV85_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBY2962130.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPAICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            7015..7662
                     /locus_tag="MIV85_002802"
     CDS             7015..7662
                     /locus_tag="MIV85_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962131.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            7664..8173
                     /locus_tag="MIV85_002803"
     CDS             7664..8173
                     /locus_tag="MIV85_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition protein"
                     /protein_id="HBY2962132.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVLVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(8537..9649)
                     /locus_tag="MIV85_002804"
     CDS             complement(8537..9649)
                     /locus_tag="MIV85_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBY2962133.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            9947..10213
                     /locus_tag="MIV85_002805"
     CDS             9947..10213
                     /locus_tag="MIV85_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBY2962134.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            10458..12185
                     /locus_tag="MIV85_002806"
     CDS             10458..12185
                     /locus_tag="MIV85_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962135.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            12185..13975
                     /locus_tag="MIV85_002807"
     CDS             12185..13975
                     /locus_tag="MIV85_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962136.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(14137..14445)
                     /locus_tag="MIV85_002808"
     CDS             complement(14137..14445)
                     /locus_tag="MIV85_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962137.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(14707..15255)
                     /locus_tag="MIV85_002809"
     CDS             complement(14707..15255)
                     /locus_tag="MIV85_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962138.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(15358..16029)
                     /locus_tag="MIV85_002810"
     CDS             complement(15358..16029)
                     /locus_tag="MIV85_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2962139.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            16425..17330
                     /gene="garR"
                     /locus_tag="MIV85_002811"
     CDS             16425..17330
                     /gene="garR"
                     /locus_tag="MIV85_002811"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBY2962140.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            17466..18848
                     /locus_tag="MIV85_002812"
     CDS             17466..18848
                     /locus_tag="MIV85_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBY2962141.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKINPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            18919..20355
                     /locus_tag="MIV85_002813"
     CDS             18919..20355
                     /locus_tag="MIV85_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBY2962142.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSEKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKILGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(20541..21395)
                     /locus_tag="MIV85_002814"
     CDS             complement(20541..21395)
                     /locus_tag="MIV85_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962143.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHTIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(21663..>21867)
                     /locus_tag="MIV85_002815"
     CDS             complement(21663..>21867)
                     /locus_tag="MIV85_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBY2962144.1"
                     /translation="SFLDESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNI
                     LVAPETDRVNLYIETCCSSFECK"
BASE COUNT         8130 a         2600 c         3526 g         7611 t
ORIGIN      
        1 ccattagcaa caatatatcc tatacgttca ccaggtagag ataatgattt actataagag
       61 tatcctataa atgaatttct atagtatttt agtacacaag gaactttggc accatcataa
      121 attatttctc tatatggctc atcagaaatt aggtatatgc ttgtattaaa ttctttttgt
      181 tttgaatcca ataattctcc aagatttttt aataattctt cagaatatat gacaccagta
      241 ggattatttg gagtgtttat tattaaagct cttgtttttg gagtaatagc attttttaga
      301 gcatctaaat ctggctcaaa agtctctata tttgtaggaa cttctattaa ttttccatca
      361 tagttttctg tataattttt atactcacca aaatacggtg caaaagcaat aacttcatca
      421 ccaggattta aaagagtttt taaaataata tttagaccac cagcagcacc acaagtcata
      481 attaaatttt ctcttgtaag atttaatcca tcttttttat ttatgtgttc agcaatagca
      541 tctcttacat cctcatatcc tgagttgttc atatatccat gaactaaatt tggagattct
      601 tcatttaaaa tatcatttat aactgcttta atagtctctg gaggttcaac acttggattt
      661 cctatactaa aatcaaaaac attttcctca ccataaatat cagaaagttt ctttccttct
      721 tcaaacatag ctcttataac agaactattt gcaactaaag tttgcatttt attagatatc
      781 atatgtaaca ctccttttta tagatttata ttgcttatgt atatattacc atatttttac
      841 tgaatttaga caattttcga aaaattactt gtttgaaaat ataaactttt atataaaata
      901 tatttatgta cagtacatat taaaaattcc aatttctaat tttatcatga ttattttata
      961 taatagtttt ttaaagaatt aataaaacat agatttagag aataaaatat tcttgactat
     1021 attaattgtt taatataata tagttgatat agtcaaacat attataatta tagaagggaa
     1081 atttaagatg gattttaaaa atttacagta tgaaagtttg tcatatatta tttgtaactt
     1141 gcaaaaaaac tttaaacttt attgtgaaaa atgtttaaaa ccatataaac ttacgaatgg
     1201 tctatatttc tatttaattt atattaataa aaataggaat tgttctttga atgatgtttc
     1261 tacagaattt gaagttgata aagctcatac aacaagaact atatctaggt tagaacaaga
     1321 tggatacata gaaaaaatcc aaaaccctaa tgatagtaga gcttttcagt tgagagtaac
     1381 agataagggt gaggaagtat taggggatat aaaaaacata ttttcaaagt gggataatca
     1441 cataaaaaaa gagttctcgg atacagaata taaggaactg gtaaagaatt tacatgtggt
     1501 aaaggatata aaaacagctg tggaggaaga ataggatgta ttgtaattta ttaaaaccaa
     1561 ttaaaattgg aaatttggaa ttaaaaaata gagtatcttt tgcacctaca agcatgggtc
     1621 ttaaattgga agaaaaaatt aaaaagtttt ctgatattgc taagtcagga gtagctctga
     1681 ttactctagg agatgtatct attagaccta gttttcataa ggtagctata agcctatcgg
     1741 atgaagatgg agtcatgaaa tacaagaaaa ttgtagatga aatacacaat tctggtgcaa
     1801 aggtatcagc acaactattt tgttcagatt atgatgttaa tttaattaaa gatactatga
     1861 atatgggaat tatttcacat gatgagataa aaaaaataat gaatgacgga gtaaaagatt
     1921 acataacaaa tatgcccaaa gaagaaatta aaaatattat aaatttattt aaagtaacag
     1981 cattgaatgc aaaaaaagca ggttttgaca tgattcaaat tcatggtgat aggcttgtag
     2041 gaagtttttc atcaagtata tttaataata gaaatgatga atatggtaga acgtgtgata
     2101 atagaagtag atttgcaagc gaaataatta gtagtatccg agatgaagtt aaggacattc
     2161 caatagacta taaatttgca ataagacaag aaaatcctca ttatggaaat gcaggagttt
     2221 tactttcgga agttgagtat tttgttaaaa aatttgaatc cctaggtgta aacagttttc
     2281 atgtaacact tgcaaatcat tcaaaattag aagatactat accaaccaat aatcatcctt
     2341 actttaaaga agaaggctgt tttttatatt tagctgatga agtaaagaaa cacacaaatc
     2401 ttccagtatg tggggttgga aaattgtcta gcccagattt tatagaaagt attatttcaa
     2461 ataatagagt agatatggtt tctatgtcaa gacaattact agcagatagg aattggttac
     2521 agaaagtaaa agatggaaga gtagatgaga ttaaaaagtg ctgttattgt aataagaagt
     2581 gtgcagatgc tttacaaaca cgctctcagt ttggatgtat actagattag aatatcctta
     2641 taaaaataaa taatttgtta aggttaatat atttttggtg atttagataa gtatttagat
     2701 aaagaggagg agacatcatg aaaagtttag ttttatattc aagtttaact ggaaatacta
     2761 aaaagattgc ttatactata tatgatgaaa ttcaagaaga aaaagacatt aaagatgtaa
     2821 atgaattagt tgattatagt attgactatg aaaattatga tatagtattc ttaggctatt
     2881 gggtggacaa gggaatttgt gataaaaatt caaaacaagt gcttgaaaat attcacaata
     2941 aaaagatagc actatttgga acaatgggag caagtaaaaa aggaagttat ggagctagta
     3001 taatagaaaa gatagaatca attatcccaa aagataatga aatattaggt tcattcatat
     3061 gtcaaggtaa gatagcagaa ggattgaaag caaaatataa agagatgtta aaactttctc
     3121 ctgacaacga acatattcgc caacaattaa ataaccatga ggaatctcaa agtcatccag
     3181 atgaacaaga aatatatgaa gccagtatgt ttgcaaaaaa tatgatgatt aaagctagta
     3241 ttgtgtagta gttaaacaat aagttcatat aagatataga ataaataatt tagtaaaaaa
     3301 gtatagcaaa taatttgcta tgcttttttt atgaaatcaa aaaaataata aaaatacttg
     3361 actgtaaacc ttgtttatac attattttat agaaaataag atagttttaa atataaaaaa
     3421 agatatatta ttgaaaggag atattattgt atgaaaactt ataaaagata attagtttga
     3481 ttttaagata tactaaatat acaattttat agagtgaaaa tatttaagac tatattatag
     3541 ttataaatta atagaataga gaggtagtgt ttaaattgca ataacagtat ttccaaagtt
     3601 gccacctcaa attcctatcc aatggaataa tggtgtagct aattatgtag ataaaaaatt
     3661 tatttatgcc taccctgtca tttgtgttgt attcagaatc cttttacgtc catttatatg
     3721 gagatggtta caaatacatg ctttttatag tgacactatt gcagattatt taacgaattt
     3781 tatgtgtttt gtagcgttgt ctatagaaat attctctata ctttttattt acaatattgc
     3841 cagacatgtt acaataatta tttttataga tatacttgta tttattgctt tactgataat
     3901 aggtatgtat aaattattta aaaaatacaa ttaattttta aaaattaagt aataagtgat
     3961 agtgtaaaaa gtagccactg caaattatgg attgtagtgg ctattttatt atttgtatat
     4021 gaaattattt tgtttttcta ataagttacg atatattatg gtttatttca ctgataaaag
     4081 gtttaggtat tttaaagtaa aaagttgtat attctaataa aatttaaaca ttttgattct
     4141 ttaaaattag agaaaataca ttgttcttat taaaaaatta aatattaaga atttaatttc
     4201 tgcatcttat ttagaaaaga taagaaatca actttatata tttttttggg ccttcctctt
     4261 tgattatcga gttttgtatt tacaatagtt gcaattcctg ctttatataa gatactcaat
     4321 attctattag cacttctaag agttatgttc atatagtttg ataatatttc tgctgacaca
     4381 ttatttgaat ttctatcatt aatcatacac atgattttag atacatttgt attagataga
     4441 ggtataaaag aagcaacttt attggctatt gagctatctt caatattatt agaattttta
     4501 tttgaatata aagggcctat tgtatcatta gtatcattta ctataaaagt acagtttcca
     4561 ttcaaagaag cagatttacc attagcttga cgagcatttt gctctgcatg aatatttgta
     4621 tttccaatgc cccaacctat atttaagcta tatttaattt cttttaaatc ttctgaaata
     4681 aaaaaatctg tatagttatt ggtcatattg tttaacattt ctttagtagt gtgtatctct
     4741 attttcatat catttttttt gacctgaact ccataaaatc catgtcttga tagagaattt
     4801 aatatagtgt tatatatttg attttgtatc tcatcatttt taaatatcaa atcttcattt
     4861 atgtactctg aactatttac tgtaactata caagttgcag atttattttt gtctaagttt
     4921 tgtaatgtta tttcattcac cagagattta aatgtattca ggattgattc tgtagatgga
     4981 accatgtaaa tacaatcata tccaagttta ttaagttcac aactaatgat gtaatttcta
     5041 gtaaaagaaa ggttaatctt attatctcgc aataagtcta aatgtatttc caataattta
     5101 tcatttaatt ttttaaagtc atatacaggt tgagggatat taaaatcttt aattgtatat
     5161 ggacatttat tagagtctat taatgaatat atatcataat aattgttgtc ctctcttaaa
     5221 aaatccataa atgattttgt aaagtcaata tctttttggc tatttaataa tttgaataag
     5281 tatttataaa aatctctttc atcaagcttt aaaaaattta atggaacttt tatgtctttt
     5341 atatttatta taagttcact atatggaact ataccactgc atacaaatcc atcaaaatta
     5401 tctacttgct catagtatat attaggtaaa ttattaaaag gattctcccc tttgagctca
     5461 ataaatgtaa tttcacaagt atcatttaat tctttaagag cttgtttaaa cttatctgac
     5521 ataaaataag atgttgtcaa aaaaccaatt ttatatttca taaaacctcc tttaaaattt
     5581 cgagagtata gtaactaatc aatcaattta taacctcatt ttataatagt agataaaacg
     5641 cgtcaattta ttttacaaaa ggaaaattta aagaaaaatc agaaaatata aaaaagactg
     5701 aaaaatatgt tgactgtcaa gaataattgt gctattttgt aattaaggac tagtctttta
     5761 agatttccta aaataaactt agattttagg aaagaaatac attttatttg aaaataaagg
     5821 agaagattat gaatacatat ttaaatgaaa tttctaagtt tgttgatgag aatagagaag
     5881 aaatagtttc attatggaaa gagattgtta atatagaaag ctatacacat tgtaaagaaa
     5941 gcgtaaataa attggctaag agattaaagt ttgagtttga aaaagaaggt ttagattgcg
     6001 agttagtaga tgttggagat aatggtagta cattgatagg tacacttggt tctaatataa
     6061 ataaaaagcc tataattttt tcaggtcaca tggatactgt ctttgaaaca ggtacatttg
     6121 gagagaatcc atttaaaata atagaaggaa aagcatatgg cccaggtgtt ttagatatga
     6181 agggtggtat aataatttcc ttatatgtta ttaaagcatt aaataaaata ggatacaaag
     6241 aaagaccaat aaaaatagta ttttctggag atgaagagat aggacataag gattcaacag
     6301 gtgcagatgt tatattgagg gaagcaaaag gtggtctttg tgcttttaat atggaaactg
     6361 gattagtaga taatagtttg tgtgtaggta gaaaaggaag aataggatgt aatatacatg
     6421 taaaaggtgt agaaacacac gcaggtaatg attttgaagg tggaagaaat gctatagaag
     6481 aaatggctaa taagatacta cgcatacaaa aattgactaa tttagatgtt ggaactacag
     6541 taagtgtaag tgtgattaag ggtggaagag tggaaaattc tattccagaa gattgtagta
     6601 taaaagtaga ccttagattt gaaaaagtag aagaaatgga gaatgttaaa gaacaagtta
     6661 gagagatatg taaagaaact tacatagaag gaacttctac agaagttaat tttataagtg
     6721 aaatgatgcc atttgaaact acagaagatg ttatgagatt tcatacattt gtaaatgaag
     6781 tgtcaaaaga aaatggattt ggagaattaa atgctaagag acttggaggt agttcagatg
     6841 ctagttattt gactattgca aacgttcccg caatctgttc atttggtgta agaggggaat
     6901 ggaaccacac atcaagagaa tatgcagtag tagattctat gtttgagagg gtgaaattaa
     6961 tttctacagt tattttaaac ttagataaat ttgaggtata aagggggatt ttatatggat
     7021 gtaacagctg gagataataa ggtaacatgg aaagggtatt tatctttatt tgtattgata
     7081 gtattatttt caggagtgtt taaagatagt caaggcttcc ttaaagcatt agattttgct
     7141 aatctgacag gttcatttgg tactattgca gatggtgtag actttatggg taaaggagga
     7201 acgggagcaa aagatggttt cttatttgct ctgactttga ttccaactgt ctgttttgct
     7261 gtaggtctta tagatgtagt tgaatctatg ggaggaatga aagcggcatc aaagatattt
     7321 aatccattgc ttagacctct gcttggtata cctggaatag caggaatagc atttgtatct
     7381 tcatttacta gttcagatgt agcctcaata atgacgaaag aattatttga aagtggggaa
     7441 ataacagatg atgaaagaac tatatttgta gcatatcaat atgctggttc agctgttata
     7501 ctgaacacaa taaatactca agctccactt ttaccaatag cattattggc attaggtcca
     7561 ataatcctta tagagatatt ctgtaaaata cttggtgcta atctagttag attaatcata
     7621 ggtgtaagaa ataaaaagaa taaggctaag gaggctgtgt agtatgagtc aacaaaatac
     7681 tggaaatgca attgtaaata gtaaacctaa gaaaactgct gttgagatat ttatgggggg
     7741 agcaaaaaaa ggtttttaca taggtgttga acagatatta ccagccatga taatgggtta
     7801 tgtaatagtg cagtttttac aattaactgg tttagttgat attttaggaa atatttttgg
     7861 accagtaatg ggtatttttg gactacctgg ggaatctgtt ttagttttga tagcagcatt
     7921 ctttgctaag gcagcaggag cagctacagc tgcaaactta tttgcacaag gtctaatcac
     7981 tgcaccacaa gcaaccatat taattatgcc atgtatgtta atgggtactc tagttggtca
     8041 ttatgccaga atagtgcttg tagcaaatgc cagtactaag tatagaatgt tactgttggc
     8101 agttcctata tttgatgcaa tagtggggat gttaatagta agagttttac tcactgttat
     8161 gggattaatg taaataacat aaaattataa cctaactata aatgatatat aagaattaat
     8221 atatacaagg attaatgagt agtaattgat atatagtaat aaactaagat agtaattaat
     8281 gtgtatatta attaaaaaaa gagagtatct caaagtgaac tttttagttc atgagatact
     8341 ctttttgtat gaaatcaagt atattttcat aatttcaaca atgaaagaga ggcttatctc
     8401 tattttgaga cagcctcttc ttttaaattt atatttctag aatttatgtt ttttatttat
     8461 ccaacattaa cattagttat tagaaataat tttaagaaaa atatactttc atgttaatat
     8521 cagaataaat ctgtttttaa aggatgattt gttttgaatt ttcacgaata tctacttcta
     8581 tgactttttc tattgtatct cctctaaaac ctaataaatt acttgtcaag tttgcagtgg
     8641 aacaagaatg attaggtata attcttattc tatcaccaat ttttatatca gtttcaccat
     8701 ttactttaat ttttccaact tcttctgaaa gtgaatcaat agtaagttct ggatgtccac
     8761 ataccctacc ataaccaaca atactactat ttccatgtgc acctttatca agtccaaggc
     8821 acttacttcc acaatcaatt aaatagtatc cactgctatt ttttgagatt acagtgcaca
     8881 caacagtaag agcacacata tcttcagtag cacaacctaa acctatctgt atagcatcat
     8941 agtatacata gtttccaggt cttacagcag ttatagtttt agaagcagct tcagattcaa
     9001 ctgttggagt actaccagaa gcgacaattt ctatattaaa tccattatca gttagagctt
     9061 tgtatgcttt ctccatagaa gaatcttctt gaacacaaac atctggaaca ccttctggag
     9121 aactacaacc atacacttga cctggatgcg aacttatacc aacaatcttt atgttttcta
     9181 gcttagaaat ttcagtagca agttcaacca ctttctctgg ttcaacccca aaacggtgta
     9241 agccacaatc tacaataata agtagcttgc actctatttt tgatttagaa aaagcttcac
     9301 tataagcctt agcacattct atattatctg tagcacagat taaatttatt tttgatgcca
     9361 tagtcacaat tctatttata tttacttctc ccatgtaagg ataagccaac ataatatctt
     9421 caaaacctgc ttttatcaga gcttcacctt catcaagtgt tccaactaga aaaccactag
     9481 cacctgcatt tttttgaagt ctcgctatgt aagtactttt atgtgtctta agcataggcc
     9541 aaagttgttt attattattt gtacaaattt gttgaatttt atctatattc ttttctaact
     9601 ggtctaaatc tagcaaaaaa tttggagtag cgacttctga aattttcatg ttatttacca
     9661 cctttcaaca aaagtaaatt aactataagt attataatta ttatattagt aatatcgtct
     9721 ttataatatt aatagcttat aattatatta tagaactagc gttaacagag agcaatattt
     9781 atttgtaata attagaattt tcaataagtt agtgtggttt taaattattt atataatata
     9841 tttttaattt tatgcaaagt ttatttaaat tagtttgagg atttattaat agggtattat
     9901 tgaatgagta aaaaagtgat gtttacatag aataatcaca ctataaatta atttagaacc
     9961 taaaaaatta attgagcaaa ttggaaaaga gaaggataaa aaagatattt ggatagttgg
    10021 tggaggcgat atagtaaaat tatttatgaa agataactta attgatgatt attatatata
    10081 tatattgcca ataatattgg ggagagggat ttcactattt aagtctggta tagataagac
    10141 taatttgaat tttaagaaag ctagtaatat tggagaactt gtaaaattgg aatacagtaa
    10201 aaaacaaaaa taaattacat gccaatttgt tacaatgtta tgaaatgaag catttaaaag
    10261 acttttggct atatgaattg acattacttg tcaaatatgt taacatataa gcgacttgtc
    10321 ggagggtgta ttaaaaagaa tatgctggag aagagagtgc gttaactctt ttctcctttt
    10381 tttataaaat taagcattta taaatttagt attattacat gattacacta tctcaaaaat
    10441 taagaaagga gaaaaatatg aaattaattt taagttattt aaagaattat aagttattaa
    10501 tagtattaaa catactggct atatttagtt ttgcattagt cgagttgggg attccaacta
    10561 taatagctaa aataattgac aatggtattg caaatcagaa tatagcttac ataaaacaaa
    10621 tgggaatagt gattgttatt atttctatta taggggttgt aggtagtata ttgttgggtt
    10681 attgttctgc taaggtatca acaagtgtaa ccagagatat aagaaatgac atatttgaga
    10741 aatcacaaga attttcacat actgaataca ataaatttgg aatttcttca atgattacaa
    10801 gaacaacgaa tgatgcattt caaattcaac aatttgttaa tatactacta aggactgcct
    10861 tattaactcc agttatgttc attataagta taataatgac aattagaaca agtgtggaac
    10921 tttctatagt attggctata tcagtacctt ttataattat tggagtagca ataatagcaa
    10981 aagtatctca ggcaatatct tcaaaacaac aaaaaggact agataaatta aaccttatat
    11041 cgagagaaaa tttaactgga ataagagtaa ttagagcttt tggaaatgat gattatgaaa
    11101 cagagcgatt tgaaaaaaca aatacatatt atgctaatgt ttctaagaaa ctatttaagc
    11161 ttatgtcaat tactcaacca gcattctttt tactattaaa tatagctgtt ttggctgtat
    11221 tttggatttc aagtgagaag ataaatattg gagagcttca agttggacag ttggttgcat
    11281 ttttggaata tcttttccat gccatgtttt caattatgct tttttcaatg gtatttatta
    11341 tgtatccaag agcagaggta tctgcaaata gaataaaaga acttttaaat gaagaaccat
    11401 tgataaaaaa tcctgaaaat ggaattaagg atactgaaaa taagggtatc atagaatttg
    11461 ataatgtaac ttttacctat ccagatggag aagcttctgt acttaaggat atttcattta
    11521 ctgcaaaaac aggtgaaaca gttgctttta taggaagtac tggtagtggg aaaagtactc
    11581 taattaactt gatacctaga ttttatgatg taacagaagg tagtattaag ataaatggag
    11641 tagatataag agaatatgat ttaaaagctt taagaaaaaa gataggattc atacctcaaa
    11701 aatcactgct ttttactggt agcatagcaa ataatattag atttgggaaa cataaggcag
    11761 gagagtcaga attagaatat tccgcaaaag ttgcacaagc atatgagttt atatcaaaaa
    11821 aacctagaaa gtttgatgaa ttgattagtg aaggtggagc aaatgtatca ggaggtcaaa
    11881 aacaaagact ttctattgca agggctatta taagaagacc tgaaatatac atttttgatg
    11941 atagtttttc tgcacttgac tttaaaactg atgcaatact tcgtgctaaa ttgaagaagg
    12001 aaacaaaaga tgcaattgta ttgattgttg cccagagaat tagttctatt attgatgctg
    12061 ataagattat agtactcaat gaaggacaag ttgtaggaat gggaactcat aaagaattat
    12121 taaaaaactg tgaaatatac tatgaaattg caacatctca gttaaaaaag gaggaattag
    12181 aataatgaaa aagtctaaag gttttaagaa aacaattggt agacttcttc catttgtaaa
    12241 gaaatataaa ttttccttta ttatagctat tatatgtata atttcagcag ctactatgaa
    12301 tgcacttgca cctaaaactg aaggattgat aataacacaa ttgactaaag atgtaattag
    12361 tatcgcaaaa ggagtaccag gggcttccgt aaattttgat tatgtaacaa aaatattggt
    12421 gattttagca tgtatatatt ttgccaatgc aatttttacg tatacttcaa gttttctact
    12481 taccaatgct attcaaaaca caatgagaga tttaagaaat gaagtcgaaa ataaaataag
    12541 aagattgcct attagttatt ttgatagtaa tagttttgga gatgtattaa gtcgtatatc
    12601 aaatgatgta gatacaatat caaatgcatt gcagcagagt tttatgcaaa ttgtaaactc
    12661 aatcttagtc ataattttgg cactttcaat gatgtttaca attaatatat atatggctct
    12721 tatagctctt tttataattc caattagtta ttttgtatct aaatttgtag taaaaaaatc
    12781 tcaaagtaga ttttcattgc aacaaaatgc tcttggaaaa ttaaatggga aagtacaaga
    12841 aatgtatact ggatttaatg aaataaaact atatggtaaa gaagaagatt ctataaaaga
    12901 atttaaaaaa gtaaatcaag aactttgtga aaatggattt aaggcacaat ttatatcaag
    12961 tatgatgaat cctatggttt cattagtaac ttactttgga attgcagctg tggcagttgt
    13021 cggttctata tatgcagtaa gtggaggaat aacagtagga aatttacaag catttgtgcg
    13081 ttatatatgg cagataaatc agccactttc acaaatgact cagttatcta cagtaataca
    13141 atcttctttt gcagctatag aacgtgtatt tgaaatttta gacgaagaag aggaaatacc
    13201 tgatgttgaa aatccagtta agatagaaaa tgtaaaagga aatgttacat ttgagcatgt
    13261 taattttgga tatggagaaa attcaacttt aatagaagat ttaaatgcag aagtaaaaag
    13321 tggtcagatg gtagctattg ttggacctac tggagcaggt aaaacaacat taataaactt
    13381 attgatgagg ttttatgatg taaagaaagg tgctattaaa attgatggag tagatataag
    13441 agatatgaaa cgtaaagatt tgcgttcaat gtttggtatg gtgcttcaag atacatggtt
    13501 atttaatgga accatttttg aaaatataga atatggtaga tttggagcta ctaaagaaga
    13561 aattatacaa gcagcaaaag tagcaaatgt tcatcacttt ataaccactc ttccagatgg
    13621 atacaatatg tttttaaatg aagaagcatc taatatatct ctaggggaaa aacagctttt
    13681 aaccatagct agagctttta tatcagaccc ttcaatattg atacttgatg aagctacgag
    13741 ttctgttgat actaggctgg aacttatgct tcaaaaagca atgagaaatc ttatgaatgg
    13801 tagaactagt tttgttatag cacatagact ttctacaatt cgcaatgctg acttgatttt
    13861 agttatgaat aatggaagta ttatagagca ggggaatcat gatgaattaa tggaaaaggg
    13921 tggattttat gagaagcttt ataatagcca atttgcagac aaagaatcag aatagataac
    13981 ataaactttt gtataaaatt ttgtatcaaa ttcaaatatt aatcatataa ttaaaaagag
    14041 tatcagtaag ttgttttttt atagatttac tgatactctt tgattttaag accaaaggta
    14101 cttatgattg gtacttataa ttcacaacta gtcttgttac atctgataac cagaattaca
    14161 gtacttttct tttttacctt tttgttctct aacatataac aattcgctta acttatcaat
    14221 gtaataacca tcatcactta tgcgaattaa actagtcaga taatatccat ctttgcttct
    14281 aggaatcttt ttatttattg ctaaatcaat agctgtcttt gctgcttcaa aatgctttaa
    14341 atgtgtatga ccttcttcaa aactctttct agtattataa actacataac cttttttaac
    14401 ttgaaaaact ataaattctt tcttttcata tattttatta aacattcaat cagcccttct
    14461 caagatagtt ttatagcata acattagaag cttctaaaaa attttacaaa gaacataaat
    14521 attttataaa ttataaatct aaaactataa tttataaaga taactttctg attatttata
    14581 tgataattca tatagattaa aagtaaatta tctttaggtt aaacaaaagt aaaataaaag
    14641 actagttata atatttatat gaaaaagtac aaaatatagt atatgaatat agaaaattta
    14701 aattatttat ttacagtttt tatttccata agtatattta ccttcagata ccttgtcatc
    14761 atggaaatat attctttcac aacttttatc tccccataga atgttttttg ttattttatg
    14821 ggacgtatct cctgtaaata cttcagctac agtagtatct gtaacatcac agtaaagaga
    14881 agcgaatttt ttaaaccaag gattttcctc aaatcttaaa agccaggaag ctccataggg
    14941 gcaatgtaac tcttcaaatt caggaaccca tcctagaaat ggaacatcag ttgtgctaat
    15001 aatattgtct gcaattaatt catctccatt ttcatgagct ctctctctca tagcaatagc
    15061 tctttcttca gacctttcaa ataaaacttt tcttaatatt tcgctagttt tatcttcacc
    15121 aaactcttca aataacactt tggaaaaata aaaatataaa tcaccaaaat gtttgcatgc
    15181 catacgaact tcttcaatag cataatcttt gtcaatagtt tcattagtta caacatcttc
    15241 gttcaaaaaa atcactcctt agaataagta ttagttacaa tataattata gaatattttt
    15301 tataaattag gaaattaatt tgagatagat atatttttaa taaatgaaag tataatgcta
    15361 aaataactta ttgttacaaa aatcttctaa attaatgtat ttaggagttt ccatatgaat
    15421 gagagtagtt ctgtaaatat cttcaataca tccatttgca atattattaa aaatatctgt
    15481 gtgctctttt aatgttgttt caagccttcc ttcatgtgac aatgaatcga gagctaattt
    15541 ttttattctg tacatataat tgttaaacat tttgtcaaat tcagtatttt gagcatatga
    15601 aactatagtt gtgtgaaata atgtatcgta ttctgcaaat gagtttaaat ttttatcacc
    15661 taataaaata tctttttgtt tatctaaaag atgttttaat ttacttatag tttctactgc
    15721 tctagcttct ttgtattgac ttgtaattaa aaaagtacaa aatccttcta ttgcagagcg
    15781 tatttggaat atctctacaa tttcatttgc tgtaatttga tggattctaa atcctttgct
    15841 tgggattata tctataaatc catcttgact aagtctttga agagcatctc ttataggtgt
    15901 tctagagata cctatttcac tagcaagttt tgtttcagaa tatatttcat tttctatcat
    15961 ttctccagat agtatcaatt cttttaagta gtcatatgct tgttcttgta atcttttaaa
    16021 tgtagccata cttaataata cccccctaaa caatataaaa atacaaaaac ttatataatt
    16081 ttaagcatac aacatagtga aaataaggtc aatcttttgc aatttaaatt gcagataaga
    16141 ttaaaaaata taaaaaatta ttgaagtgtg aagcatgatt aacattaaag gcagattaat
    16201 taaaactaat tgaaattagt taaaatacaa aactgtaaaa gtagtatatt atatttgaaa
    16261 acaatagtat gtattaaaac ttatatagga tgactaaata taataaatga ctttaaaaat
    16321 tactatttat tgttaaaata aatactttta tattttatat tgaccggtat actggtatgt
    16381 agtatactct aaaacataaa aaacgttttc aaaaatgtga agatatggag ggttataaaa
    16441 tgaaattggg atttattgga ttaggaataa tgggaaagcc aatggcaaaa aatttattaa
    16501 aagatggatg taatcttttg gtgtatgaca ttaataaatc tgctgtggat gaacttatat
    16561 catgtggagc aaaatacgca agtgttttag aaatgggtca agaatgtgat attgtattta
    16621 caatccttcc aaatggaact attgtgcagg atatattgtt tgggatggat ggattggcaa
    16681 aaactttaaa agaaggaagt atagtagtcg atatgagttc agttactcct acagaatcca
    16741 tattgtgtgc aaataaatta aaagatatgg gcttagaatt tatagactca ccagtaagtg
    16801 gaggggagcc aaaagcgatt gatggtacac ttgcttttat ggctggtggt aaggaagaaa
    16861 tttataagaa agtagaacca ttttttaata taatgggaag ctcatctatt ttaattggag
    16921 ataatggtag tggaagtgtt acaaaactta caaaccaagt aattgttaat ttgacgatag
    16981 cagcagtttc tgaggcattt gtacttgcag caaaagcagg tgcagaccca gaaaaagtat
    17041 ataaggcaat aagaggaggc ctagctggta gtacaatatt ggatgcgaag ataccaatga
    17101 ttatgaatcg tgattttaaa ccaggtggga aaatatctat taatttgaaa gatattaaga
    17161 atgtaatgca aacagcacac aatttagatg taccactacc tatgacaagt caattattag
    17221 aaattatgca gacattaaaa gtacatggac atttggaaga tgaccatagt ggaatagcac
    17281 agtattttga aaagttggca ggtgttgaaa taaaaaaaca caataattaa tatttaaata
    17341 tatcaatata attaaataca tattattagg attagattat ataaatacag cgaggttaag
    17401 ttatcatagt aaaagaaaaa taaaattgat aaataataaa gtagaatgat aaaggggtaa
    17461 agattatgat tacaggatat ggacttttga tagcatttgt tatatctata ggaattttac
    17521 ttgtatcgat tattaaattt aaaataaatc cgtttttggc attactgata acatctataa
    17581 ttacaggctt tatggttaga atgcctataa atgaaatatc aaccacaata tcgactggat
    17641 ttggaaatac attaggtagt ataggtattg taattggact tggaataata tttggaaata
    17701 ttctttcaga atcaagagca acagaatcta ttgcaaaggg gttgttagct aagactggag
    17761 aaaaaaacag tgctttagca gtaactacag caggtttttt aatttcaatt ccagttttta
    17821 tggatgcagc ttttgttata atgatgccta taattaagta tgtttcgaga gtaactaaga
    17881 aatctctaat ggtttttgta tgtgccttag gagttgggac tatagtaggt catgcacttg
    17941 taatacctac accaggacct ttagcagttg cagcaaatgt aaatgcaaat gtaggtagtt
    18001 ttatacttta ttctataatt gttgcttttc cagcagctct tataggtgga tggatttatg
    18061 gaaaacgttt tgaaaaatat ccagcttatg ctattgatga gaatgataga gaaaaaaatt
    18121 tagagcaggg aaaagatagc ataaaaattg aagatgatga ttcttctaaa gtaccaggtt
    18181 ttggaatttc tatgttttct ttattgttcc caatacttct tatacttata tcaaatgtat
    18241 ttagtatgtt cttagaaaaa ggttctacaa tgagtggagt acttgcattt ataggagata
    18301 aaaacatagc aatacttctt ggaatattgg tggcaatagg atttttaaag aaatacataa
    18361 ataaacctat gggagatgta gttattgaag ctgctgattc agcagggcta atattattga
    18421 taacagggtc aggtggtgcg tttggcagtg ttataaatgc aagtggtata ggtaacttct
    18481 tagttgatac tatgtctggt cttagtatat cagttgtagt gcttggattc ttattaagtg
    18541 ccttgcttag aatttctcaa ggttctgcta ctgtagcctt agtaacaaca tcatcaattt
    18601 taggacctac aattttggca actggaatgt caccagtttt agtagggctt gctatatgtg
    18661 ctggaggagt tggtttctcc cttccaaatg attctggatt ctgggtactt tcaagattta
    18721 gtggattatc agttaaagat actttaaact cttggacaat tggaggaacc attgctggag
    18781 ttgtagcatt tataatggtt ttattgctta gtgttataaa tggaattata ccacttccag
    18841 gtctataaat aacaaactat tgtttatatc atataaatta catttagact atacaaatta
    18901 cataaagggg cgttttaaat gagagaagta aaaccaatta gcatagatat acttaatact
    18961 tttaaacaag tagatgagga cagattaaat aaacttcttg cagatgagct taagcattta
    19021 gatagaaaaa ttgttgtatt agatgatgac ccaacaggtg tacaaacagt tcatgatatt
    19081 tctgtttata ctgattggga taaggatagt atggaacaag gttttaatga gaaaaatagt
    19141 atgtttttta tacttaccaa ttcaagggga tttactgttg ctcaaactac aaaagcacat
    19201 aaagaaattt caaagaatat tgtggatgta tcaaagaaag ttaataagga ttttataatc
    19261 ataagtcgta gtgattctac tatgagagga cattatcctc ttgaaactaa tttattaaaa
    19321 agcgaagtag agagattatc ggagaagtta tttcagggtg aaataataat gccatttttt
    19381 aaagaaggtg gtaggtttac tatagataat gtacattatg ttaaagaagg agaaatactt
    19441 gtaccagcag gaatgactga atttgcaaaa gataaatctt ttggatataa atcatctgat
    19501 ataggtgagt ggtgtgaaga aaagacaaat ggaaagtaca aatctagtga tatgatatat
    19561 atttcgtcaa aagaacttag agagctaaat attgaagcta taacagaaaa acttaaaaaa
    19621 gctgaaggat tcaataaaat tattgtaaat gcaaccgatt atgtagatgt aaaggtattt
    19681 acaattgcgt ttatacgagc agtaaatagt ggtaaggaat ttatgtttag aagcgctgct
    19741 gccataacaa aaatacttgg cggagtgagt gacaaggaac tacttactaa ggatgaatta
    19801 gtatcaaaag gtaataccaa tggaggaatt atacttgttg gttcacatgt gaataagact
    19861 acccaacagt tagaagaact taaaaattgt aaatatccga tagaatttat agaatttaat
    19921 caacatttag ttcttcaaga aaatggtcta aaaaatgagg taaaaagagt tataaaagtt
    19981 gtagaggaaa aaataagcag gggtaaaact gttgctgttt atactagacg agagcgtttt
    20041 gacttggata cgaatgataa agataaacag cttatgattt ctgtagaaat atcagatgca
    20101 gttaccagta taattggtat gcttaatgta agaccaaatt ttattatagc taagggtgga
    20161 attacttcta gtgatgttgg tactaaagca ctaagagtaa aaaaagctac agtaatggga
    20221 cagataaaac ctggtatacc agtatggatg acaggcaaag aaagcaaatt tcctaatatg
    20281 ccatatataa ttttccctgg aaatgtggga gagattagca cacttagaga atcagttgag
    20341 atattgatgg ggtagtatat tagtgtattg aagtttaaac gcttaaattt actgagttaa
    20401 aattaaaata aactaaaatt ataaattaag attaaaaata atagtatatt aattagggtt
    20461 tagagtattt tacaaaaaat attctaaacc ttaatcttat gtattagtat ttttattatt
    20521 taacttatgt gtttatttta ttatttatct tttttaattg atttaatatt ttctttgatt
    20581 ttatttaaaa tatctgtatg cttattagag cttatgttgg ggaatgcttt gattatacgt
    20641 ctatgaagta atttgtggtt agacagcaaa gtattaagtt tattttttag ctcatcaata
    20701 cgatttttag catagcgata attttctttt tctttaagta tttcaaacct atcttccaaa
    20761 gtatccagtc tattttcaac taaagattca agtttgtttt ctatagtttc ttgtgtaata
    20821 agtttgtagt attctttctt atcttttaat tccttaatta taagattgat ttgttttaac
    20881 ttaccattta attgtaaaat tgtatggact gtgataacta aatctaaaac aaaataaatt
    20941 tctatagata tagcaaatat aaatagcaca tttttagaga tagagttaat aaagtcaacc
    21001 acaataggat gtactataag cattacaatc aatgataata caccaaacat aagtgagttt
    21061 tccagacaaa ctcttccgtg aatattaaat ttatgtttag aataatccca ccaagtcata
    21121 ttaaatattt tttctaaaat aaagctcgta caatactcca ttatgctagt tataattata
    21181 ctaaacaaaa acaacaaagg aatagtgtgt acaaaaggag tcaaggtagc aactattgct
    21241 aatgctccaa atccatatat agggcaaaat ggaccattta aaaaacctct atttacaaat
    21301 tgtttttgta aaactgaaca atatgtagtt tcacaacacc atcctataaa gctataaatt
    21361 acaaaataaa gaaattgaat ataaaatgta ctcataagca cctcatttct agttagtata
    21421 acactatata ctcgatattt tatttttatg attaatttac taaattcaat ttacatattg
    21481 attataccaa tttatagaaa tttatcaaat ttaattacag ttagaacatt ataaacatgg
    21541 ttataataat gaaattttat ttaaaataaa taagggtgtc aagtataatc aaactaatag
    21601 ttgtagatac tctacactat gttagtttaa ttacatttga cacccttata tttatactat
    21661 gactatttac attcgaaact agagcaacat gtttcaatat aaaggtttac tctatcagtt
    21721 tcaggagcaa ccaatatatt atcaagtgta cataagctac catctttgtt gtatttacaa
    21781 ttttttacag tacaaactaa ttcctcacaa tttctattat taacgttgct agataaatta
    21841 ctataaatag attcatctaa aaatgaa
//
LOCUS       DAGQVA010000067        21827 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.067, whole genome shotgun sequence.
ACCESSION   DAGQVA010000067 DAGQVA010000000
VERSION     DAGQVA010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21827
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.067"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(8..2602)
                     /gene="clpB"
                     /locus_tag="MIV85_002816"
     CDS             complement(8..2602)
                     /gene="clpB"
                     /locus_tag="MIV85_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBY2962145.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(2639..3235)
                     /locus_tag="MIV85_002817"
     CDS             complement(2639..3235)
                     /locus_tag="MIV85_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962146.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(3252..3656)
                     /locus_tag="MIV85_002818"
     CDS             complement(3252..3656)
                     /locus_tag="MIV85_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBY2962147.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            4023..4397
                     /locus_tag="MIV85_002819"
     CDS             4023..4397
                     /locus_tag="MIV85_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2962148.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            4394..5257
                     /locus_tag="MIV85_002820"
     CDS             4394..5257
                     /locus_tag="MIV85_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962149.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            5257..5895
                     /locus_tag="MIV85_002821"
     CDS             5257..5895
                     /locus_tag="MIV85_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBY2962150.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            6387..6800
                     /locus_tag="MIV85_002822"
     CDS             6387..6800
                     /locus_tag="MIV85_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962151.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
     gene            6991..8208
                     /locus_tag="MIV85_002823"
     CDS             6991..8208
                     /locus_tag="MIV85_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBY2962152.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            8370..9068
                     /locus_tag="MIV85_002824"
     CDS             8370..9068
                     /locus_tag="MIV85_002824"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBY2962153.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(9288..9905)
                     /locus_tag="MIV85_002825"
     CDS             complement(9288..9905)
                     /locus_tag="MIV85_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBY2962154.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(10032..11054)
                     /gene="argF"
                     /locus_tag="MIV85_002826"
     CDS             complement(10032..11054)
                     /gene="argF"
                     /locus_tag="MIV85_002826"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBY2962155.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            complement(11163..12350)
                     /locus_tag="MIV85_002827"
     CDS             complement(11163..12350)
                     /locus_tag="MIV85_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBY2962156.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYVERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(12380..13240)
                     /gene="argB"
                     /locus_tag="MIV85_002828"
     CDS             complement(12380..13240)
                     /gene="argB"
                     /locus_tag="MIV85_002828"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBY2962157.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            complement(13255..14472)
                     /gene="argJ"
                     /locus_tag="MIV85_002829"
     CDS             complement(13255..14472)
                     /gene="argJ"
                     /locus_tag="MIV85_002829"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBY2962158.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEAHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(14513..15547)
                     /locus_tag="MIV85_002830"
     CDS             complement(14513..15547)
                     /locus_tag="MIV85_002830"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBY2962159.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKIASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(15801..16014)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16232..16999)
                     /locus_tag="MIV85_002831"
     CDS             complement(16232..16999)
                     /locus_tag="MIV85_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HBY2962160.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKQRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     gene            17298..17771
                     /locus_tag="MIV85_002832"
     CDS             17298..17771
                     /locus_tag="MIV85_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962161.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(18140..18697)
                     /locus_tag="MIV85_002833"
     CDS             complement(18140..18697)
                     /locus_tag="MIV85_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2962162.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSFL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            18955..19653
                     /locus_tag="MIV85_002834"
     CDS             18955..19653
                     /locus_tag="MIV85_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2962163.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNIPTKILYGKHDELTEIGVVEKFVEKFNCNLTIVENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            20669..21136
                     /locus_tag="MIV85_002835"
     CDS             20669..21136
                     /locus_tag="MIV85_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBY2962164.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            21147..21362
                     /locus_tag="MIV85_002836"
     CDS             21147..21362
                     /locus_tag="MIV85_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962165.1"
                     /translation="MAIVVNLDVMMAKRKISLKELAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
BASE COUNT         7477 a         3317 c         2408 g         8625 t
ORIGIN      
        1 tcttttatta tttaactaaa acttcaatat tttcatcttt tccatctata actatagtac
       61 atccattata cacatctcca gcaataagtt tctttgcaat tatagtttct aatgtatttc
      121 ctatatatct cttaagaggt cttgctccat atacagggtc atatccttct ctcaccataa
      181 catcttttgc tgaatttgta acttcaatag taatatcttt ttcttttaat ctatttttta
      241 aatctttcat aaatatatct ataattttct tgatattttc ttggtctaaa ggcttaaaca
      301 ttataatatc atctactctg tttaaaaact caggtttaaa tctatgcttc atttcattca
      361 ttactaaatt gttagtagtc tctgttatat ttcctcctgc ttctaataga taattacttc
      421 ctatattaga agtcattatt ataagagtat ttttaaagtc tactgtctta cctttattat
      481 cagtaagtct accatcatct aatatctgta agaacatgtt aaatacatcc tcatgtgctt
      541 tttctatctc atcaaatagt attacagaat aaggagcacg tctaactgct tctgtaagtt
      601 gaccaccctc ttcatatccc acgtaccctg gaggaggtcc aactagtctt gatacagcat
      661 gtttttccat gtattcagac atatctattc ttattatatt atcttcacta tcgaataaat
      721 ttctagcaag agtttttgca agttcagttt taccaacacc tgtagggcct aagaaaataa
      781 atgaaccaat tggttttctt tcatctttta atcctgctct tgcacgtatt actgcatttg
      841 aaactgctgt aactgcttca tcttgtccaa taactctttt atgaagttca tcttctagtt
      901 taagtaattt ttctctttct ccttcaacta gtttagttac tggtatacct gtccactttg
      961 atacaatgct agatatttct tcttcagtaa cttcttcttt taaaagagaa ttttcagaac
     1021 catcattcat attttcttcg tactgcttta tttgttcttc taacttaggt atttcaccat
     1081 atttaacctc tgctgctttg ttgaaatcat attctctttc atacttttca gctttacctt
     1141 tagcttcgtc taattgagcc tttaagtttt taatatctaa tatttgactc ttttcttttt
     1201 catattttgc tgtcatttca tcatttttag attttaactc tgctatttct ttttgaatat
     1261 catccaatct tgatttactt ttatcatcat tttctttaag taatgcttct ctttcagttt
     1321 ctaatgtaaa taactttctt ctaacaacat ctaattctgt tggcaatgaa tctatttcac
     1381 tacgaatcat agctccagct tcatcaatta aatcaattgc tttatctggt aaaaatctat
     1441 cttgtatata tctatgagaa agttttgctg ctgctacaat agcattatca tgtattctta
     1501 ctccatgatg tatttcaaat ctttctttta aacctctaag tatagatatt gtatcttcaa
     1561 cagtaggttc ttctgcaatt acaggctgaa aacgtctttc aagagcctta tctttttcta
     1621 tatactttct atattcatca aaagtagttg caccaataca gttcaattca cctcttgcaa
     1681 gcataggttt aataagatta cctgcatcca ttgaaccttc tgttttacca gctccaacaa
     1741 tagtatgaat ctcatctata aacagtataa tttttccatc agaactttga acttctttta
     1801 aaactgcctt taatctttct tcaaattcac ctctatattt tgcaccagca attaaagctc
     1861 ccatatcaag tgagaataca atcttatctt ttaaaccttc tgggacatct cctcttacta
     1921 ttctctctgc taacccttct acaattgcag ttttacctac acctggctca ccaatcaata
     1981 caggattatt ttttgttctt cttgataaaa ttcttataat ccttcttatt tcttcatctc
     2041 tcccaattac agggtctaat ttatttttct tggctaaatc tactaagttt gttccatatc
     2101 tagcaagtgc atcatatgtg ccttctgggt cttgtgtttc tactctttga ctacctctca
     2161 cttgtgataa aatatttaaa aagtcattct tatttatatt atattgtttt aatattttac
     2221 caacagctga ttttgattct gtttccatca ttgcaagcat aacatgttct acacttatat
     2281 atgaatcttt aaattcttta gaaatactct ctgcctttat aagcacctca tttatttttc
     2341 tagtagctga tactccttgt gagtcagcac cttctccata tacttttgga agcttatcaa
     2401 tttcaaagtt tacagtattt ctcaaagaat caattgatat attcattttt tcgattatat
     2461 ttggtatcaa tccatcctct tgattaataa gtgctgagaa aagatgaatt acatctactt
     2521 gttggttatg attttttact gcttcgttat aagcctcatt taaacttttt tgaactctta
     2581 aagtcatttt ttctacgtcc atataaatcc ctccatttta atattatatc caaataaatt
     2641 aaattctctc atttataatt attgattttc taagctctaa aagactatca agtaaattct
     2701 cgtttttttg tatatcgaaa ctcaatgtta aattaaatgt tccatctgaa ttaaaaaaat
     2761 cgaatacttc ttttgatttt gctattaaat acaagtcttc atctataagt cttttttcac
     2821 ctattaataa atactgacat ttatctataa aactcttttt aaaatcaata gtgtatagat
     2881 tttctaaaat attatattga taaatagcaa tattattaaa cacttttaat atgtttgaat
     2941 ttacaaaatt gtaaatttga ttattgttat acagtgatat ttgttcgtat atatattccc
     3001 taaataaagg atgaatgttt tgcttaagtt ttaaagtaac ttcagctggt atttcaaaat
     3061 aaagcttcca gtacttagag ttattttttt ctaaaataaa agctactttg ttcaaactgg
     3121 tagaactaat ctcctttagt gtacaattaa aattatagtg tctcaaacta gttttttcat
     3181 tctcaaatac atagtcaaac cactgtagaa catttctatc aagttttaaa ctcatataaa
     3241 aaccttcttc cttatttact aaccttatta ggtcttttta tctgattata ttctgctaat
     3301 aaactttctt tatcagctct actaccttta tatgctatat gtggatttat catatactca
     3361 ccatttttca ctctttgtaa aaaatccatt tttttcagct ccgtaaacaa tgaagataaa
     3421 gaagtttttg gatattcaaa ttcacaagat aattcatata atgtttttct aatcttatta
     3481 tttttatcca tagagtttat taattttaat ggaattaaat ccctcttagt atacattcct
     3541 tctactactt taatataatt cttaaaacaa acattcatat acttactttt attcataact
     3601 aaacttttgc tctctgtata ttcctgattt aaatcctttt ttaatgtctt atccaaatta
     3661 aatatctctt ctcactctcc ttatctctaa ttgataatat aaatatatta caaaaaaata
     3721 tgtatgtcaa aactgaaaat gcaaaaagtt caccttataa gtaaactttt atttagctat
     3781 aagctaaact ttattatttt tttaatttag tatttccaat ttattggcag gatttttgaa
     3841 caatatttat aaatttttta aaaaaattta aatctattta atatggcaga ctttcataaa
     3901 atacattaca tttattaaat gtataatatt ggcaattagt tttttctaaa atcagttgac
     3961 atattatata tatatttata taatgtgtat atactatata tacaatttaa ggaggtgtct
     4021 tattgaatat agttattagt aattcgagtg ggaagccaat atatgaacag attactacac
     4081 aaattaaaag tatgattata agtggagagt taccagaagg ctcagctctt ccaagtatga
     4141 gactattggc aaaagaactt agaataagtg taattactac aaaacgagca tatagcgatt
     4201 tagaacgaga cggatttatt gagacagtta ctggtaaagg cagttttgta tctagtaaaa
     4261 acatggattt tgtcaaagaa gaacaatttc gtttaattga agaataccta caaaaagcag
     4321 ttgatacagc aaaaagtagt gatattacat atgacgaatt aaaagatatt ttatttttat
     4381 tatataaagg agaatgataa gtatggatgc aataactata aaaaatttaa ataaaactta
     4441 taaagatttt agcctacaag atatatcttt ttcagtacca aaagggagtg taatgggatt
     4501 tgtaggtgaa aatggtgcag gaaaaacaac tacattaaaa gcaattttaa atttaatatc
     4561 ttatgatagt ggaaatatag aaatctttgg tcttgatagt aaaaaaaatg aaaaagaaat
     4621 taaagagcaa attggggttg tatttgaggg aagcaacttt catgaaaatt taaacactga
     4681 ccatgtttca aaaatcatga gtaaaatcta taaaaattgg aatgacacat tatttaaaga
     4741 ctacttaaaa aaattgagag taccagacaa taaattaatt aaggagtttt caaaggggaa
     4801 taagatgaaa cttagtattg ctgtagcctt atctcataaa ccaaaattat taatactaga
     4861 tgaggcaact agttcacttg accctatcgt tcgtgaagaa atactagata tatttttaga
     4921 ttttatacaa gatgaagaac actctattat cttatcttca catattacaa gtgatttaga
     4981 taagatagca gactatatta catttataca taaaggaaaa attgtattta gtgaaaataa
     5041 ggatgaatta attgatacta tgggagtttt aaaatgtaaa cctagtgatt ttgataacct
     5101 ttcaagagag gattattcat attatcgtaa aagccaattt ggatatgaag tacttcttaa
     5161 agataagcat agatttatct caagacatcc aaactgtatt gttgataata cgtctataga
     5221 agaaattatg ttattttatg tgagaggtga taaataatga aaggtctaat tttaaaagat
     5281 ttacttaatt tgaaaggaaa tataaagttt atacttttat tcatcattat gtttggcttt
     5341 atgtcttctt taggagatgg aaatgttaat aactttatag gtgttattat agttttatgt
     5401 actacaatga ttgtttcaac attttcatat gatgatttga ataaatggga tagttatgta
     5461 cttacaatgc ctattaatcg caatgatatt gtattaagta aatatttaac tatgttaata
     5521 tttagcttta taggtgttct tgtttcactt attgttagtg taactattgg ttattttaaa
     5581 aatacactta tattaaatga aacactactt attaatgcac taatcttatc aatttcagta
     5641 tgttttggta gccttattct accacttatt tataaatttg gtacagaaag agctcgttta
     5701 ttaatgattt tatgcttttt agttccaaca ctagctttat tagtttttaa aagtatttta
     5761 gaaaatatta gttcacctat ttctatagaa attatactta atacactagt atattctctt
     5821 ccatttgttg ctattttact atttgtgatt tcatatttta tatcatcaaa aatctatagt
     5881 aaaaaagaag tataaaatat actatatatg tttctgtatt taagtattta aataaaatac
     5941 tatcgagttt attttggtag tattttattt tttaattatt aatctctact aggtatttat
     6001 tattttatta cttatattta ataagactat ttactacttt ctaatcttat ttatataatt
     6061 tattcatttt ataaattgaa ctactaatga tattattgaa catagcaata gaataacatc
     6121 taaaatagtt tttatgtatt aaattaactt attttaatat tcaacaattt aggtttacta
     6181 aatttattga tgatttcttt ttatataact taaactacat ttttatttaa aaaaatttaa
     6241 tatcaacaat ataaaattaa gaataagtat tattagtttg acattagcat aaatgcctat
     6301 tagaataatg ttaaactata ttctttctac tgattttatt aaaaaatacc aatatacaaa
     6361 agattataca aggagaaagt tcaaatatgg aattagaaat tacagaaaaa atagaaaaac
     6421 aagatgaaga tactattttt caaggattat taaaatataa tcttgctaga cttgaagata
     6481 aaaacccagt ggatttagga atatatattc gagataaagc aggtaaaatt gttgcaggtt
     6541 ttataggtgt tactcatggt aattggcttt ctataaaata cttatgggtt agtgagaagc
     6601 ttagatataa aggtactgga agtcaacttt tatataaggc tgaaaaaatt gctaaagaac
     6661 gaggttgtaa atatgttttt ttagatacat tcagttttca agcacctaaa ttttatgaga
     6721 aatttggata ccataaagta ttttcacttg aaaattatcc tctaactgga aagagatatt
     6781 attttagaaa aatactataa taataaaaat catattttat atttttaact taaaacttct
     6841 gctcttcgtc tacagacttt atatttttat atcattatta atactaaaat agtattttac
     6901 tatacataca aaattatttg aaagttcaaa aattataagt ataaaagcta atcttagctt
     6961 aaataaaaat tatattttta ggaggtaaat atgttaggaa aaaaatgtat ggattatcta
     7021 caaacattag gaaaaataag ttcaacaaca aatggtctta caagacttat cttgactcaa
     7081 gaacataaaa aatctattga tttaattagt tcatggatgg aaggtttaaa tcttgatatt
     7141 gaaattgatg acattggaaa cgttataggt acatataaat caagctttcc aaatgctccc
     7201 acattagtag ttgcatctca tcaagatagt gtaaagtgtg gaggtatatt tgatggtatg
     7261 ttaggtataa tagtgcctct agttggtctt gaagaagcaa aacacaataa taggtcttat
     7321 cctttcaata ttaagctaat tgctttcgct gaagaggaag gaactagatt tgaaacttct
     7381 ttaatgggaa gtaaagtttt tgctggtact tttaaagagg aacttcttaa atctgttgat
     7441 gaaaatggaa ttacacttga agaagctgta acaaagtttg gatttaatac aaaaaactta
     7501 acaaatttgc atcctagaaa agatgtagat gcatatttag aatttcatat tgagcagggt
     7561 cctgttttag aaaatgaatc tcttcctgct ggaattgtat caagtattac aggatttaaa
     7621 agttttaaga tatcagtaaa tggtaagtct ggacatgctg gtacacttcc aatgaatatg
     7681 agacttgatg ctggatgttg tgcctgtgaa tgtgtattag ctatcgaaaa agtagctaaa
     7741 acgactgctg atttggttgc tactgtagga aagatgaatt tctatccatc ttcatcaaat
     7801 gtggtacctg aaagagctga atttactctt gatgtacgct cttgttcaca agaaattctt
     7861 gataattctg tagaaaagat atttaatgaa atatcacata tatgtgaaaa tagaaaactt
     7921 aattatacaa gtgaacttgc ttttgaaaat gttcctgtac catgttctaa taaaataaca
     7981 aaaatcatag aaaaaagttt tatagattta aatcttaatc ctttttatat ttatagtggt
     8041 gctggccatg atgctcagga aatggataat ataactgata ttggtatggt atttataaga
     8101 tgcgctgggg gcgtaagtca taatcctaat gaaagtgttt ctgtagatga cttggatact
     8161 gctgtaaaaa tatttttaaa aatactagat aatcttgatt taaaataatt cttatataag
     8221 aaagtatatt aaaatatata atctaaaaaa tcactttata tttatattat ataagtgtac
     8281 aatataatct attataaaat ataattttat gcttttatag atttttattt tatacataaa
     8341 tatatttata tataaaggag ataattttta tgaatgaaaa attaattggt attttggctg
     8401 gaatgggtcc aaggtcaaca gccccttttg ttgatttaat tattgatgag tgtcaatctc
     8461 aatatggagc aaaatatgat gatgaatttc caaagatgat gatatattca ttacctaccc
     8521 cattttatat tgaccgtcca ataaatcatg aacttatgaa agaaactata attgatggat
     8581 tacaaaagct tgaatcaact ggtgtaaatt ttattgcaat gccatgcaat tcagcacata
     8641 tatactttaa agaattaaaa gagtctatta atataccaat attaaatatt gtagaagaaa
     8701 cagttaaaaa attacctact atctcacaaa aagtaactct tttttcgact agttcaactt
     8761 ttgagtctac aatttaccag aatggtataa tacataatgg acatgaattt atatttaaag
     8821 atgaatggca aataaaatta aacaatctta ttcaaaatat aaaaatggat aaagaaaatc
     8881 cacacaatat tgatatttgg aataaactta tcgaagatgt taaaaatgaa tctatagaaa
     8941 atatagtaat tgcttgtact gatttaaatg tagttttaga aaaatcatat ccttcaataa
     9001 atattgttga ttcatcaaaa tgcttggctg aatcagttgt caataaatat ctaaaattag
     9061 ttaaataaat ttttcatgca ctatattata aaaaatatat gttataagtt tattttaaat
     9121 agtatagact tataacatat atcatagttt cttgacaata tagaaattaa ccatgtattt
     9181 cattatatta ataaaaagga taccaaaaat ggtatccttc ataaatattt atatgtttat
     9241 ttataaaaat aatcatatat ttattacttt actacaccta aacaatatta ttcaagtgta
     9301 ttcatagagt tagaaaattc ttgtcctgct gtaacaagat tagataacaa tacatcagct
     9361 actgcatcat ttactgaact tattatccat ttattatcct ttttagaaca ttcaaactct
     9421 acattttttg taacataagt ctctttaacg cttttttgtt tttctttcat aattgatact
     9481 aacatttcag ttgttttctc atcagttaag tcttgtcctg aaaaactcat accaatcatc
     9541 tttgtaaatg cctcagctac tatttcttga agtaatggtg ttgaatctat aaatttacat
     9601 tctactttga ttgtagcctt atcaccttta acctcgctgt cttttattgt atatgtgatt
     9661 ttagatgcat tctgttttag ataatctaaa acatattggg catttgggtc ttttgtatct
     9721 aattccttta atatatcctt atatttttcg tcattatttt ccattacctt attcatgcct
     9781 tcaaagtcaa actttttcgc actgttaaaa aaactatcaa ttgtatcttc tggttttgca
     9841 cttgaacatg ctgttaaaga tattgctaat aaaaaagttg ttaaagctaa tatgattttt
     9901 ttcatatctc aaatcctccc tcttaatttg ttgatacata agttatttta acatataatg
     9961 agagtttttg aataatatat ttaaaatatt ttataaattt tcattaaagt aaagtctata
    10021 ttaaaacata tctatattaa attattgttc atatttacat cagtcatagt agaaaccata
    10081 acagctttta ttgtatgcat tctattttca gcttcttcaa atacctttga atattttgaa
    10141 ttaaatacct cgtttgtaac ctctaattct gataatccga acttttcata aatctcctga
    10201 gcaaccttag tttctaaatc atgaaatgct ggaagacagt gtaaaaatat aacattttca
    10261 ttttcagttt tctttatcat atccatattt acttgataat ctttaagttg atttattctt
    10321 gcttcatatt gctcctcttc tcccatagaa acccatacat ctgtatatat aacatctgca
    10381 cctttaacat catcaatatt ttcagtcaac attatatctc ctttggattt cttggctatt
    10441 tccttcattt ccttaaccaa ttcttcattt ggccaaagtt ccttaggtgc tagtgctacg
    10501 aaatgtattc ccattttagc acatcctatc atcagtgagt ttcccatatt atttctagca
    10561 tcaccaacat atacaaattt aactttattc aaatctttat ctacattttc aattactgtt
    10621 aaaaaatctg ccagtatttg tgttggatga tattcatctg taagtccatt ccaaacaggc
    10681 acaccagaat attttgctag actttcaact gtttcttgtt taaagcctct aaattctatt
    10741 ccatcataga atcttcctag aacttttgct gtatctgata cagactcttt tttacccata
    10801 tgacaatcat ttggacctag ataagttaca tgtgctcctt catcatgagc tgctacttca
    10861 aatgaacatc tagttcttgt tgatgttttc tcaaataata aagctatatt ttttccttgt
    10921 agcaaatcgc cttttatacc aacttttttc ttagttttta aataacttga taaagttaat
    10981 aaatatctaa tctcttcttt tgtaaaatcc tttaatgtca aaaaactctt accttttaaa
    11041 cttatattat tcatattaat tcgccccttc ttataaactt tttaaattca attaaacttg
    11101 ttagcacttt acttttttat ttacttctaa tttttatctt taatcaacta tttcttgaat
    11161 atttagttaa tttctagtaa tatatctttt aggatttcaa gagcctcatc tatttcctta
    11221 taactgattg ttaatggtgg taaaaatctc aatacatttt ttccagcagt caaaataagc
    11281 aatccttttt ttctagcttt ctcttctata atactagatt caatattagt ttcaattcct
    11341 atcattagac caataccttt tgtctttaat acaactttgt tattaaaact ttcaatagat
    11401 tttcttatat aatttccttt ttctaatact tcattataaa aaccatcttt agatatctca
    11461 tctaatacaa ctgaagctgc caccatagct aataaattac ctccaaaagt tgtaccttgg
    11521 tctccttttc ctagtacttt tgaaagtttt ttatttacta atactcctcc tactggtatt
    11581 cctgctccca acccttttgc tacggtaact atatctggtt ttacatcaaa atattcatag
    11641 ccaaaaagtt taccagttct tcctataccg cattggactt catcaaaaat cactacaata
    11701 tccttttctt gacatatttt tactatttcc aaaacataat ctttttcaag aacattaact
    11761 ccaccttcgc cttgaatcgc ttcaagaatt attgcacaaa ctgtggaatc aagattattt
    11821 tttaaatctt caatattatt tctttctaca tatttaaaac cttcgggaag aggataaaaa
    11881 tacttatggt atttgtccat accagttgcc attaaagaca tcattgttct accatgaaaa
    11941 gagtctttta aacttatgat agttcctcta ccattaccat atttgtcact actatacttt
    12001 cttgctattt tgaatgctgt ttcatttgct tctgttccag aattacaaaa atatacttta
    12061 gccattccac ttgaattaat tattttctct cctgaataca acactggctc attaaaatat
    12121 aaatttgaag tatgtaataa tttatctact tgctctttta gagcattctt taaattacta
    12181 ttactatacc caagagaaga tactccatat ccacttgtaa aatctatata tttattgcca
    12241 ttagtatcaa aaaaacaact tccttcacca taatctatga caaaattggg ttgattatat
    12301 gtatctataa aatattcatt ccattttgaa attgtattgt cgttattcat tcttattctc
    12361 ccctcttaaa cttataattt tattcatttt cttttcttat taatgtacct attccactat
    12421 cagtaaatag ctctgttatt atagaatgtg gaactcttcc atccaaaata tgtaccctat
    12481 ttactccgtt atttaaggca tctacgcatc cctctatttt aggtatcata cctccagtaa
    12541 ttataccttc ttcaaataat ttatcaacat cctctaatat aacttctgtt attaatgatt
    12601 tttcttcatc tggctctctt aacaaaccag ggacatctgt aagaagtatc aatttatctg
    12661 catttaactc tttagctata gcagaagctg ctgtgtcacc atttatatta taagtctctc
    12721 catcatctcc aacacctata gttgcaatta ctgaaatata acctgacttt agacaagatt
    12781 ctataagctc aacatttact tttttgattt ctcctacaaa tccaagttca taatttttat
    12841 atgggtcaca taaaatcata ttattatcta ttccacaaag ccctactgct tttccacctt
    12901 ttgtatgtat tttatttact aggtctttat taacctttcc agcaagtacc atttttacaa
    12961 tttccatggt ctcttcatct gtatatctaa gaccatttac aaatttactt tctatatcca
    13021 cttttgctag catcttattg atttctgccc ctccaccatg tactaaaact atattgattc
    13081 caacataact cattaacaca aggtcttcca taacagattc ttttagacca tcttttttca
    13141 ttgcacttcc accatactta actacaatag tctttccctg atgtttttct atatatggta
    13201 aagcttctat aagtgtattt gctttttcta tattaatcat taaagtatat cctcctaatt
    13261 tctataactt ccatttattc ttacataatc atagcttaaa tcacatcccc atgcatttcc
    13321 tctggcattg cccatattta aatctactaa tatacttatt tcgtcatctt caaggatttt
    13381 ttttgctttt tcctcattaa aatctaatcc atttccattt ttacatactt caatatatcc
    13441 tttcatactc tcaaaaataa tatcaacttt ttccatatct atttcttcac ctgcataacc
    13501 taaagcacac agtattctac cccaatttgc gtcagctcca aatacagctg tctttactaa
    13561 tgaagaagat ataactgttt ttgctaattt tactgcatgt gcttcactta atgctccatt
    13621 tatatagcat tcaattagtt ttgtacatcc ttctccatct tttgcaacaa gtttagcaag
    13681 ttctatacag acatatgtaa gtgcactcaa aaatacttga taatgttcat cttttttgtt
    13741 tattctatca ttttttgctt ttccatttgc tagaatcatt accatatcat tagtacttgt
    13801 atctccatct acactaactc tattaaaact tttgtcaaca gcaattttta aagcttcttt
    13861 tagcaaaact ccatcaatat ttgcatctgt agttataaat cctaacgttg ttgccatatt
    13921 aggatgtatc ataccagaac cttttgccat acctccaata gttatttttt tatctccata
    13981 cattattgct actgctattt ctttttttat aatatcagtt gtcataatag cttctcttgc
    14041 tccaatatga ccttgtttac ttagattatt cactaattca tccatatttt cttctattaa
    14101 atctatattt aatggctttc ctataacacc tgtagatgca accaaaacat cactttcttt
    14161 aatatttaat ttatcactgg tgaatttagc cattttataa gcatttataa gtccttcttt
    14221 tccattaaag gtattagcat tagcactatt tactatgata gcttgtgctt ttccattttt
    14281 aatgtgttcc tgtgtaacat aaacaggatt gccctttact ttattttgag ttactactgc
    14341 tgctgcatca cataaaacat ctgaataaac caaagctaaa tctctttttt ctttattttt
    14401 tctcaagcca cagtgaatcc ctgaagcaaa aaatccttct gaaactgtaa ctccaccctt
    14461 tataatctcc atatttatcc tcctaattat atgagtttag tattttttat ttctaaaatg
    14521 atggtgcaat attttttaaa cctgtatttt cttcaatacc aaatattata ttcatgtttt
    14581 gtatagcttg acctgctgct cccttaatca tattatctat agctgaacag attatcaatg
    14641 tatctccatt ttcatgtaat gatattacac atttatttga gaatctaaca ttctttaaag
    14701 aagctatctt atctaatgga agaatttcta taaattcttt aaattcataa taatcagtta
    14761 atttcctatg tatatcattt atagaaatat tatcttcttt tgtacaatat atagttgata
    14821 agattcccct atttactggg attaagtttg gtgtaaaaac tacacttact ttttctttgc
    14881 aggattcact taaattttgt tctatttctg gagtatgtct gtgtttccct attttatatg
    14941 cagtgatatt ttcattaacc tccgtaaagt gactactaat cgataattct ctaccagcac
    15001 ctgtaagacc tgatttagaa tcaattatta tattattatt ttttatcaat ttagaactta
    15061 gtaatggcat caatggtaaa gaaatactag ttggataaca tccaggattt gcaattatat
    15121 ctgcatcttt tatatcttct ttgtatattt cacttaatcc atatacagct tttttatgta
    15181 agattttatc tataaaagat actccatacc atttactata tacttcttca tcttttattc
    15241 taaagtcagc acctaaatct ataactttct ttttcgattt aattgccttt attacaaact
    15301 tttcactaac tccatgtgga agggctgtaa acacaacatc acacatatct ataacttttt
    15361 cattttctat acatatcatg ttatttttat atcctatact tggatatata tcaactatat
    15421 cttttccaac atacgaattt gaacctatcg ctgtcacttc gactttatca tgattcatta
    15481 ataatctaat caactctgcc ccgacatatc cagttgcacc aataatacca acttttattt
    15541 tattcatttt gttccctcca tttttatatt caaatagtct taaaatccta tctttccact
    15601 ttactatatg ataatcattt gataatacgt agattaaaat actctaatta aaacaaaaaa
    15661 ccccttagca ttataaatac taagaggcga ttttccgcgg taccactctt attggtaaaa
    15721 ttacaataat cattaaaact caaattaaaa agtatctaca aaatgtacat ttaaaattaa
    15781 aaaagcctct tggtcaaaga ccaagagacg aatatacacc cgcgttacca ctctaattga
    15841 taagataatc ttacccactc taatctctta aggcgagatt caccaattac catactatta
    15901 cttctggtaa tctcctccaa agctctattc acaataaaat tcgttactag gcttccacca
    15961 ttcccagctc tctatcaact agctttatgc tactctcttt ttcacaggat ttcaatttat
    16021 tttcttattg ttttatatga tagtttattt ttttaacttt gtcaatataa tttttaaatt
    16081 tttggaaata ttttctatat ggttaatttc cagcattttg tatctaaatt gcgatataat
    16141 ttttatattt cattcgtcaa tttaaaaaac atccaaaata tattaaatta taaaataata
    16201 tattttcaaa atacaatatt tacatctctt tttaattaaa ttttttaatg ttggtatcta
    16261 aaaatttctc aatctttttc tcagaaagta tctcgttggt tacaaattca ccattaaaaa
    16321 aaagactgta tgtagtaaat ggtgcaggag cattttgtgc ttcttttgct gtttcgaatt
    16381 ttataagatt tacatcaata cctctagaat ttgcaatttt tttcaaaata ggagcatatt
    16441 tttccgtatg tggacactga ttactgtaat ataaaactat accattctca tttaattttc
    16501 tttgttttac acaattctta aaacatggaa taggagcatt atcagtaaag ggaaaatata
    16561 atagctcata atttggttct gatgtatctg ctaaacaaaa gtccttatat tttagatatt
    16621 tagcatcaga taaaaaaggc atttttttac tagacgaaag cacaactaat ccatatttac
    16681 cttttgattt tgcatcatca acacactctt gtagcaatag attagaatat ccttgaccct
    16741 taaattttcc agatatccaa aaacagttaa taaatatata attgtccgca gtaataggac
    16801 accatgcatt ttctgctgga atatattcta taaaagcttt acctcttaca tcaaatcgtt
    16861 taaagactag acctttatca aaattatttt tcatccaagc ttttttagaa aaaacacaat
    16921 tttctccttt tttttcagaa attgaacaac atatatgttc attgtcaata ttatttatat
    16981 ttatatcaat aatctgcata cttatctcct tttctaattg cataataatt tttaaatata
    17041 ttctatatat ttttatctta atattttgaa tacaacaaca tcatgtcata tatattttta
    17101 ttttacataa tattatttta agattatctg aattattaaa ttgtatatat aattaaatac
    17161 attctatggt ctaactacac tataatataa attatatatt atcataatat tctaaattta
    17221 taaaacaaat tgtattgaat tgaatttatt taagatatat aattataatt aaaataataa
    17281 taaaggtgtt gtttataatg ttcaaagaat acttaataag agaattaaaa gaagatgata
    17341 ttaaaaatgc attagactta atctggaacg tatttgaaga atttgaatct ccagattatt
    17401 gtgatgaagg aattacgaca tttcatcaat ttatagaata taactctatt attgaaaaaa
    17461 tcaaagaaaa aactctcttc ttttggggtt gttttgactc taaaaaactt attggagtct
    17521 tagctattag aaatttaaat catatatgta tgttatttgt agataaaaac tatcataaac
    17581 atggtgttgc aaaaaaatta atgactacag gcatacaata ctgtatttgt aataaattta
    17641 atttaactga aataactgta aattcatcac cttatgctgt tgaagtttat cataaattag
    17701 gatttaaaga tactgctgtt gagcaaattg ttgacggtat acgttttaca cctatgaaat
    17761 tgttaatata ataaattaaa taaaaagcaa agtctcttaa atattttata gttactttgc
    17821 ttttaaacca agatttaaaa taatactatc ttttttgttt tttaataata tactttaaaa
    17881 tccttactaa tatgaactat aatttatttt ttgatatcct ttttgattaa catataaatt
    17941 aattcaatta ttaaacataa actatgttgt ttctctttat atctcttctt tgtaaacaat
    18001 attgggcatt tgaaaataaa tattcttaaa atatactgtt ctcctgttga ttttcctttg
    18061 gtacaaatga taaaaattta atttacatgc cccataatga agtgttcaat aaataagtta
    18121 aaataattta tttacctcct taatcatatt ttttatgaat acctaataac acagtatcaa
    18181 tagaatcgac taaacctttt atagcttctt ctttactcaa aaatgatttc ccaagttgca
    18241 aagtcgaata accatgaagt acactcatta ttaagtttaa tacttcacct gtattctttg
    18301 tatttagatt acaagaaaga ataagttttt ctaataagga tttatattca tcaaagattt
    18361 ctaatgtttc attatttcca tgccaagtag cccactgaat tgtttcataa acaccaggat
    18421 tagaaattat aaaattaaag tatgctatac ttatacactt tatagctgta tctccaaaat
    18481 ttccaatagc cgcctttatc atttgactat tcatctctct cattccttta tgagctactt
    18541 caagtaataa atcatctaga ctttctatat gattgtacaa agatggtgta cgtattccta
    18601 gcttttctgc aataactttt aaagaaactt tgttaagccc atctttatta actatatctg
    18661 atgtagcttg tataactatt tctctactaa cacgcatgat tttccctctt tcatttaaaa
    18721 ttaattactt tattagttta actaatctaa ttagtttcgt caattattgt aatttataaa
    18781 attctttata ctattataaa atcttgacag tttaattata atttaatata atactaatta
    18841 aattagtttt aatactaata taattagtat tatattaaat tctatattac aacattattt
    18901 tatagtttga ttaatttaat aatcactaat atatcaaact gaaaggagat ttttatggaa
    18961 aaaaaatatt tcgaaattca tggagttcct tcaatccttt ggggaaatcc ttcaagtaaa
    19021 ttatatattt acatacatgg acaatgtggc aataaagagg aggctgaagc ttttgctaat
    19081 attgcagttc cacatgagtg tcaagtttta agtgttgatt tgcctgaaca tggagaacgt
    19141 aaaagagaaa aaaattcatt taacccatgg catgttgttc cagaattagt atctattatg
    19201 gaatatgcaa agtgccactg gaatcaaatt tcgttatatg caaatagcat tggagcatgg
    19261 tttagtatgt taagctttga aaaagagaac ttaagagagt gtatttttgt atctccaatt
    19321 ctagatatgc aacagctcat ttcaaatatg atgctctggg caaatgtatc agaagaacag
    19381 cttaaacatg aactaattat cccaacttca tttgggcata ctctttcatg ggaatatcta
    19441 caatatgtaa aacaacatcc tatcactcaa tggaatatac caacaaaaat attatatggt
    19501 aaacatgatg aacttactga aatcggtgtt gtagagaaat ttgtagaaaa gtttaattgc
    19561 aaccttacta ttgtagaaaa tggcaaacat tggtttaaca caccacaaga attaaattca
    19621 ttatatgaat ggttaaatac tttagttaaa taaaaaataa ttatattatt aatatgatta
    19681 aattatttat aaatgttatt taattaattt tattttagca ttattaaaat aactacataa
    19741 agaataaatt agttattatt aaagaaatta aaagtatata gagtattaat aattttttaa
    19801 taattagtta ttatagaaaa aagagggata taatattgtc tccctctctt tcttctgtaa
    19861 tattatataa tttttattta tcactctcaa taaattatag ttatctacaa aattcaatct
    19921 ttaatacatt attaatatat tgtgatatta atattacagt attaaataaa atctaataaa
    19981 attaactata aaatatctat tatataaata tccactctta tgtttgaaat ccgtcatata
    20041 gttttatcct tcttatcttt tatatcaata acttttttta ataaaattga caaaactaaa
    20101 gtaaaaaacc ttattgataa tgaaacaaat gatactataa gttctgatat tatagtaatt
    20161 gcatataaat agacatcata aaaataatat aatattgtca ctataaaatt aaatgtaaaa
    20221 atctcaaatc taactaaata cacatatagg tattttttaa gtttttaggt atttcttctg
    20281 aaaatgattt attgattgat accaatttac ataatctttt taatataaac aatgatacaa
    20341 tatatgggac agcacatatg tatatagcta cttatattac agttggcata ttcgtatttg
    20401 taatgcttat accaatttta aaatacacca tcagtactaa tagtattaaa ataatctata
    20461 ataaagttaa aattattcca attagtacaa tattatttaa tattttacaa ctcatatcct
    20521 tttttatata aatttaccac cttatacatt cttattttta gtgtatatta caatggtttt
    20581 atatattata tcaatatttt attattgaaa ttcaataaat tatatattat aatcaataat
    20641 atactttata taaaggagat gatattttat gattacaaaa ttttttagta atatattatc
    20701 agtatttcta tattttctat tatcactttt aggagttgct ggtataatat tcttatgtat
    20761 gatacctatg tttttatatg attttagttc tgacaaagta attgctttaa ttgcaagaat
    20821 actatatttt tctgactact ttatagtcat cttattcttg atatttataa ttaatagtac
    20881 taagtattcc ccattcgtac ttgaaaatgt aaaaaggttt aaagtaatgg gattttgttt
    20941 attgataaac actataattg aatgtatcaa tggttataat ttaaatacta ataatataag
    21001 aatttttgga actgatagtg gcggtatctc accacttatg gttatctctt ttatatttgc
    21061 actaatgtgc tttgtaattg cagaaacatt tgataaagct ataaaaataa aagaagataa
    21121 tgatttaacg atatagaggt gatgttatgg caatagtagt taacctagat gtaatgatgg
    21181 caaaaagaaa aatatcactt aaagaattgg cagaaaaaat agatattaca aatgcaaatt
    21241 tatcaatttt aaaaactgga aaagcaaaag ctattagatt taccactcta aacgaaattt
    21301 gcaaagcttt agactgtcag ccaggtgata tacttgaata tgtagaagat gaaaatgatt
    21361 aaaaaagagt gtttagaaac actctttttt attatactat atgattttta ttcttttact
    21421 atattattga cattaatatt aactttgttt aaagtcataa caaaatatgt tctaagaaag
    21481 aaactgttcc tttatctatt tgttatccat tacctataag aactgtatca cactaaataa
    21541 tacttttaaa ttgataattt taccacagat tcctatatac attcttttct acataatatt
    21601 tatttaaact gttagcaaaa catggaactt tttcatttac ttatacctcc atttatatta
    21661 ttgcatagct tatagctatg tgttataaat tacattattg atgattttat ctaacatttg
    21721 taatctttta gatactcttt gaagttacaa cactgttata ctctaattaa gtaaactaaa
    21781 tctgatacaa gttggtgatt atatgaaaag aaaactttca acctatt
//
LOCUS       DAGQVA010000068        21797 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.068, whole genome shotgun sequence.
ACCESSION   DAGQVA010000068 DAGQVA010000000
VERSION     DAGQVA010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21797
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.068"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            151..1749
                     /locus_tag="MIV85_002837"
     CDS             151..1749
                     /locus_tag="MIV85_002837"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBY2962166.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1984..4065)
                     /gene="bclA1"
                     /locus_tag="MIV85_002838"
     CDS             complement(1984..4065)
                     /gene="bclA1"
                     /locus_tag="MIV85_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBY2962167.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGVTGEIGPTGVTGPTGVTGSIGPTGATGPTGATGVTGEIGPTGATGPTGNT
                     GVTGATGPTGNTGVTGVTGATGPTGATGVTGEIGPTGATGPTGEIGPTGATGPTGATG
                     VTGEIGPTGVTGPTGEIGPTGATGPTGVTGSIGPTGATGVTGEIGPTGPTGVTGSIGP
                     TGATGPTGNTGVTGVTGPTGATGPTGVTGEIGPTGATGPTGVTGEIGPTGATGPTGPT
                     GNTGATGSIGPTGVTGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNN
                     GDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFP
                     ILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATL
                     TIFRIADTVMT"
     gene            complement(4743..5267)
                     /locus_tag="MIV85_002839"
     CDS             complement(4743..5267)
                     /locus_tag="MIV85_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBY2962168.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(5332..6084)
                     /locus_tag="MIV85_002840"
     CDS             complement(5332..6084)
                     /locus_tag="MIV85_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBY2962169.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(6115..7413)
                     /locus_tag="MIV85_002841"
     CDS             complement(6115..7413)
                     /locus_tag="MIV85_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBY2962170.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVKSTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(7430..9694)
                     /locus_tag="MIV85_002842"
     CDS             complement(7430..9694)
                     /locus_tag="MIV85_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBY2962171.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(9949..10767)
                     /locus_tag="MIV85_002843"
     CDS             complement(9949..10767)
                     /locus_tag="MIV85_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBY2962172.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(10760..11458)
                     /gene="cbiQ"
                     /locus_tag="MIV85_002844"
     CDS             complement(10760..11458)
                     /gene="cbiQ"
                     /locus_tag="MIV85_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBY2962173.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(11461..11739)
                     /locus_tag="MIV85_002845"
     CDS             complement(11461..11739)
                     /locus_tag="MIV85_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2962174.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(11729..12481)
                     /locus_tag="MIV85_002846"
     CDS             complement(11729..12481)
                     /locus_tag="MIV85_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBY2962175.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(12663..12855)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(12987..14759)
                     /locus_tag="MIV85_002847"
     CDS             complement(12987..14759)
                     /locus_tag="MIV85_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBY2962176.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(14773..15702)
                     /locus_tag="MIV85_002848"
     CDS             complement(14773..15702)
                     /locus_tag="MIV85_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2962177.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            15931..16119
                     /locus_tag="MIV85_002849"
     CDS             15931..16119
                     /locus_tag="MIV85_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962178.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            16112..16813
                     /locus_tag="MIV85_002850"
     CDS             16112..16813
                     /locus_tag="MIV85_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962179.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            16815..17738
                     /locus_tag="MIV85_002851"
     CDS             16815..17738
                     /locus_tag="MIV85_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2962180.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRVQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            17895..18818
                     /locus_tag="MIV85_002852"
     CDS             17895..18818
                     /locus_tag="MIV85_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962181.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLANDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            18811..19548
                     /locus_tag="MIV85_002853"
     CDS             18811..19548
                     /locus_tag="MIV85_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962182.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            19559..20332
                     /locus_tag="MIV85_002854"
     CDS             19559..20332
                     /locus_tag="MIV85_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962183.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIMSLLLCACLSAFILKGLKHNEKN"
     gene            complement(20873..21481)
                     /locus_tag="MIV85_002855"
     CDS             complement(20873..21481)
                     /locus_tag="MIV85_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBY2962184.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(21659..21775)
                     /gene="rrf"
                     /locus_tag="MIV85_002856"
     rRNA            complement(21659..21775)
                     /gene="rrf"
                     /locus_tag="MIV85_002856"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6924 a         3790 c         2863 g         8220 t
ORIGIN      
        1 atattaaatt tgtagtattt atgtaagaaa taaattttat ataatatttt ttcactaaat
       61 ttttttcttt ttacaacaaa tactcactac cttttgatat aatattttta tcaattatta
      121 ttatattcaa gttttgaaag gagtattaaa atgagtttat tagttttcgg acataaaaat
      181 ccagatacag attcaatatg ttctgcaatt tcattagcac atttaaagaa caaactagga
      241 ataaaagcaa cagcttatgc tttaggagat atcagaaaag aagctaaata tgccttggat
      301 tactttaagg tagatgcacc tgaaatttta gataatgtta gaatacaagt tagagattta
      361 aattatgata aagtagtacc tttaacacca acttcatcta tattagaggc ttataacctt
      421 atggatgaaa aaaatgttaa aacactacct gtaacttatg atgatggaac ttttgctggt
      481 atcattacta tgaaagaaat agctaaaaat ctacttcatc aacactttac aactatacac
      541 acatcactat caaacatttg taaaaacctt aatggtacta ttcttgtgga ctgtggtgaa
      601 gatataaaag gtagagtagt cactttatca tttggaatgg agactctaat agagacttta
      661 aaagaaggag acatagctat tgttggagat agatatgata gtattgaata tgctattgat
      721 acaaaagtta aacttttaat acttactaat catacagaga tttcaaaaga tttgctagct
      781 cttgctaaga taaatggagt gtctgttgtt tctgttgaaa gtgacaatta taaaacttct
      841 aatgtaataa atcaatgtag tttcttagac tctatagaag ctacagaaaa tttaattaca
      901 ttcaaagaag atgattatat ggatgaaata aaagagatta tgctagaaac aaacttcaga
      961 tcttatccaa tattagatga tgataataag tttttaggtt tagtttcaaa aggtcatcta
     1021 ttaaacccat ctaaaaagaa tgttgtttta gttgaccata acgaatatgc tcaaagtgct
     1081 gatggaattg aacaagcaaa catagttgaa ataattgacc atcataaact tggcggtatt
     1141 tctactgatg ttcctatgtc atttagagtt atgcctgttg gatgcaatag tactataatt
     1201 tatcaaatgt acaaagaaaa taatgttgag ataccttatg aaatagctgg gcttctttta
     1261 tctgctatat tatcagatac attattattt aagtctccaa caacaactga tatggataag
     1321 aaagcttgtg aagaattaag taaaatagca aaagtagaca tggaaaaata cgctatggat
     1381 atgtttaaat gcggtacttc tttagatgaa tatactatag aagaaatagt aaatatggac
     1441 tttaaagaat ttaatatgag tggacataga gttggtattg gacaagtatt taccttagac
     1501 atagactcta tatttgctaa aaaagatgag tttttatctt atataaattc gactgattat
     1561 gataaattaa ttctttcagt tacagatata atcaaagaag gttcttattt aatctataaa
     1621 gcagaagata gcttaattgc taacgcattt ggtgttgaag gtgttcaagg cacatttgca
     1681 ccaggtgttg tatcaagaaa aaaacaatta gtccctaatt taactactgc aatcaaaaat
     1741 tttaaataat ataaaatttt taaataacga aaactgtctc aaatctatat ttgagacagt
     1801 tttttattat atatatattg ataataaagt taaataaaaa tccataaatt taaaattttt
     1861 atgaatatat tttattatta ttgttatttt attcattcta aaataggtaa aactcaatat
     1921 ataaaaatac ttttgtcatt taaataaaac ctaaatagtt tttaagatta ttttagacac
     1981 gttttaagtc ataacagtat cagctattct aaatatcgtc aaagtagccg cagttcctgc
     2041 tgattgccca tttcgtatcc ctactgttgt agatgaaaag ttatttattg taaaagtagt
     2101 cccaccaaat aaaaaaccag caaaatatcc agaaagtact cctccgcctc ctggctcagt
     2161 agtaagccct gccaaatctt ttcctcctaa aattgggaat aggatagcga aagaatattg
     2221 atttatactt gatgaacctg gttgtaatgc tactgaaact gatatataat acacaccatt
     2281 ttcttgtact gtaaacgtac catttgcatc tactgttata cttgaactat ttcctattat
     2341 tgtttgccaa cctgttatag catctccatt atttagtgtt tgtggagatg gtgcatttac
     2401 gaggaagtta gcaactggct gagaggaatt gcctgttgct cctgttggac ctgttgggcc
     2461 tgttactcct gtcgctcctg ttgctcctgt tggacctgtt actcccgttg gccctatact
     2521 tcctgtcgct cctgtatttc ctgttgggcc tgttggtcct gttgctcccg ttggtcctat
     2581 ttctcctgtt actcctgttg ggcctgttgc tcccgttggt cctatttctc ctgtcactcc
     2641 tgttgggcct gttgctcccg ttgggcctgt tactcctgtc actcctgtat ttcctgtcgg
     2701 tcctgttgct cccgttggtc ctatacttcc tgtcactcct gttgggcctg ttggtcctat
     2761 ttctcctgtc actcctgtcg ctcctgttgg tcctatactt cctgtcactc ctgttggtcc
     2821 tgttgctcct gttggtccta tttctcctgt tgggcctgtt actcctgttg gccctatttc
     2881 tcctgtcact cctgtcgctc ctgttgggcc tgttgctccc gttggtccta tttctcctgt
     2941 tgggcctgtt gctcctgttg gccctatttc tcctgtcact cctgtcgctc ctgttggacc
     3001 tgttgctcct gttactcctg ttactcctgt atttcctgtt ggacctgttg ctcctgttac
     3061 tcctgtattt cctgttggac ctgttgctcc cgttggtcct atttctcctg tcactcctgt
     3121 cgctcctgtt ggacctgttg ctcctgttgg tcctatactt cctgtcactc ctgttgggcc
     3181 tgttactccc gttgggccta tttctcctgt cactcctgtt gggcctgttg ctcccgttgg
     3241 gcctatactt cctgtcactc ccgtatttcc tgtcggacct gttactcctg ttggtcctat
     3301 acttcctgtc gctcctgtac ttccggttgg gcctgttact cccgttggcc ctatacttcc
     3361 tgttgctcct gtatttccgg ttgggcctgt tggtcctatg cttcctgtcg ctcctgtact
     3421 tccggttggg cctgttactc ctgttgggcc tgtacttcct gtcgctcctc ttggtcccat
     3481 tggacctgta attctaattg gaagacactc acatttagga taacaattat ctataattct
     3541 atcttcaaat gttacaagta tatacggttt gttacaacct ctactagatg taaattcaag
     3601 aatctgataa gggtaattta aagataaagc taacccataa ttaggatatt tattcattgc
     3661 ccatgctttt atagttcccg taatatttaa acaaatatag ttggatgtat cacttatccc
     3721 aattggtaaa tatcccctga tattttccat agacactcta tcattccatg ttatagttcg
     3781 taaattataa tattcactta ttcttttaat ttcaatatct actttttctt taaaaatatg
     3841 attcttattt gaatcaatat gaataaataa ctctgctttt aatatacttt tgtcttttaa
     3901 tatatctggt attctcactt taaaaaaagt aatcaacttt tcttttacaa aactatttga
     3961 acatttactt cctattaagc aataatctaa attactaaag tttttatctg gatatttttt
     4021 agatataaaa gtatcatcat ttaaataaag tataatattt ctcatttata atccctccat
     4081 tttgggtcta tatcatacta tgtttaaaat acatgcttag ttacaataca attaaaattt
     4141 atagtattaa atttttatat aataatgctg atttctacaa aaaaagaaca tgtcattaga
     4201 aatttctaat agcatgttct ttttcattat tatatattac actttaaatt attccttgac
     4261 tggcttagct ggtgtaaact aaaccagtct ttctaaaata ttaagcactt ttttcttatt
     4321 atgtttttta ggatttattg tctatattat tgtaaaccaa agttataaaa ttgtaaatag
     4381 aatatattac cataacaata tttttttata agtaaaaatt ataaaaaact ttatttttgt
     4441 taaatggaat aaataaaata agtttaaaaa atactgaaat aagtgttttc cacatatttt
     4501 atatatttat ttaatacatt attatttaaa aataaatata taaacaatca taataaaatt
     4561 tttttaataa aactttattt tttagttaaa atcatacaat atatagattt ccacaataca
     4621 aataaattaa aaagtgaaat gtatttgtct aaaaacataa taacatttca ctttatcctc
     4681 atttttaagt aatatatatt tttaattttt atttataact aaatctagtt tttatataaa
     4741 ttttagtttt tttctacatc tgagtaatct attccaaaag tttctacagt aacagatttc
     4801 ataatttgtg gagtttgtgg cttatcagct gaatctgttc taactgatgc tatttcatca
     4861 actgtatcca taccttctat cactctacca aaacctgcat actgaccatc taagtgtggt
     4921 gagtttttat gcattatgaa aaattgagaa ccagctgaat taggtgccat agttctagcc
     4981 attgatatga ctcctctttc atgttttaaa ttgttagtaa atccattacc actaaattca
     5041 ccttttattg agtgacctgg accacccatt cctgtaccat ttgggcatcc tccttgtatc
     5101 ataaatcctg gtattactct atgaaatatt attccattgt aatatccttc atttactaat
     5161 gatacaaagt ttttaactgt atttggagct atatttggat ataactcaat tttgatttct
     5221 tttccatttt ccatttctat agttactata ggatttttat tttccataat ttattacctt
     5281 ccttttcatt agttaaatta cataattaca tttattatat tatactctaa attaaagtct
     5341 atcaagtata ttttttccta tttcatatcc ttcttgataa atagttttac aaaactcatc
     5401 atcaaagtta agcgtgtctt taggagcaaa ttgagtatta ggtctaacta ctattatttt
     5461 atcttcatca tatacttttt taatatcttc tggcaactca taattatatt ttgtggatat
     5521 taaaataatt ttatccacat tatccccaat taatggttca attaatgcac tcctaattaa
     5581 acctccatct aatttgaaac catcataaat tccttcttgc acatctttca caaattgttc
     5641 tttaaatcca agagttgcgt ttggatttga tggtaacaac ccactgtatg aaatgctgat
     5701 aatggcttca ttacgaggca tttttgatac atcaacaatc ttttctgata ctactttatt
     5761 atcaacttca acataattaa cataaaagtt catttcttct atattactat catctagttc
     5821 ccttaggttg tctatagcag gagaattatc cacagtatta tttactattt ttacatttcc
     5881 attctggata tcttttatat ttgtccacat tttctccaag ttatcaacat tccctgtgta
     5941 caaataatat ccatttattg ctcctattga tgtccctgaa atcgaataaa atttatttat
     6001 tcctccatca tacaaggctt taactactcc tgcttgataa gccccttttg ctcctccacc
     6061 ttctaaacat aatcctaatt tcatagtctc atctccaaat tgtttatctt atatttatat
     6121 ttcaaaaaac ttactaaatg ttttatatat actatagtgg tcctcaacat ttcctaattc
     6181 tcttatagaa tgcattgcta aaattggact tcccacatcc acagatggta tatctatatg
     6241 agtagaagat attggaccta tagtacttcc tcctctttca tctgacctat taacaaattc
     6301 ttgatactca acattagctt ctctacatat atttttataa atagctatag aatatccatc
     6361 actagtatac gcctgactag catttatctt tataaccgga ccttttccca ttattggttt
     6421 attagttggg tcatgctttt ctggaatgtt tggatgaata gcatgagcta aatctgatga
     6481 tatcataaaa gatgaataaa tagactcaaa gaatccctct ctatccttac ccattgatat
     6541 acaaattctc tccaatatat ttaacaacat gtttgaatct gcaccttgtt tagtagagct
     6601 accaacttct tcattgtcaa atacagccat tacatttaca ccatgttgac ctttagtatt
     6661 aacaagagca ttcaaactag catgtaccat tgcaagatta tcttgtctcc caatagatat
     6721 aaattcatca ttagccccta ttaaacttcc tttttcaaat tcatataaaa ataaatcaaa
     6781 atctataata tcgtccatat ttacatctaa gttagatgct atttgcttta taagaaaatt
     6841 atctttttct aatgtatcat ttaacatccc aactaaaggt aacatatctt tttgcttatt
     6901 atatgaatga ccatcattta tacttctatt taaatgtatt gctagatttg gtattataca
     6961 aattggcttt ttaaagtcta taagcctttc atttggtttt aatatactat caccttttaa
     7021 aactactcta ccagctatcc caagaggtct atccaaccat gtacttaata ttgctcctcc
     7081 atagcattct gtatttaact tcaaataaga tttttcagct tctatttctg catttggttt
     7141 aatactaaat gtaggagaat ctgaatgaga gcctattatt ctaaatccat ctctttctat
     7201 atcttctgaa tttactacaa aagctactat agctgataaa ttcttagtaa cataatactt
     7261 tccaccaact cttagattcc atctttgatt caaaactaat tcttcaaatc catttttatc
     7321 taagatttcc ttagtactct tgactgcatg aaaagacgac ggactatcat atatgaagtc
     7381 tattaagttt ttagcaaagt ttatactatc cattcctcat ttacctccat tataaaatat
     7441 ttagtgttgt atattcttta tttatttttt taattccctg ttggtcaaaa gctatagtaa
     7501 catctgtacc aattatagaa accactgtcc caaccccaaa tttaggatga tgtaccttag
     7561 aaccaagttt tatatcatct ggattagttt ctttattaga atcttttatt gtagcattaa
     7621 ctttatctgc aactttagat ttgcttatag tactcatata ctttttagta tatttatcta
     7681 acatattata acttgcttta gaatagctta gttctttttt tactttgtac aatctttcta
     7741 tacattcttc tggcagttct tccataaatc ttgaagctat tgcaacattt gttttaccat
     7801 ataatgttct cttctctgtc aatgacatat atagctcttc tttagctcta gttataccaa
     7861 cataacaaag tcttctctct tcttctattt gtgaatcact catagatttt atagctcttg
     7921 atataggaaa taacccttct tccatacctg ttaaaaacac aacagggaac tctaaacctt
     7981 tagatgtatg aattgtcata agcgaaaccc tatcattgtc ttcttcatca tttgattcag
     8041 atgtaagtgc tatacttgtt aggaatgtct ctaagtcttt attttcataa gtatcatcat
     8101 tactactttc aaactccaaa gctatagaaa taaattctct caaattatca attctgtctt
     8161 gagcttcttc acctttgcct gttaaatctt tttcattttt atttcttatc tctacaagct
     8221 cgtccatata tcctgtagtg tccaagactt tttctataag tttgctaaca ggataaactt
     8281 cttttatagt tctaagagtc cctataatat caacaaatcc acttatactt gcccttgcct
     8341 tagtagatat atctgaattt gtttctatat caattaatac tgagtatata ctttcctgtt
     8401 ttaagttagc tctatcttca attttttcta tggttctaag ccctatacct cttctaggaa
     8461 catttataat cctttttata gatatatcat cttgtggatt ttgaataact cttaaatacg
     8521 ccaacaaatc ctttatttct tttctctcat agaattttgt accaccatat atattgtatg
     8581 gaatttgact tctatttaaa gcgtcctcta caggtcttgc ctgtgcattt gctctataaa
     8641 gtactgcaaa atccttataa ggtctatttt cttttctagc tatttgtgca attgaatcag
     8701 caatgaaatc agcctcttct atttcactac cagttaattg tatctttata agttctcctt
     8761 cttttttttc actccaaagc ttttttcttt ttctttctat attattagat ataactttat
     8821 tagctgcatc taatatcact tgtgtagacc tataattttg ttccaacttt acaacatgta
     8881 cattgtcata atctttctca aattcaagta tgtttcttat atctgcacct ctccatccat
     8941 aaatactttg gtcatcatct ccaacaacac aaatattttg atgttctctt gctaataatt
     9001 ttatcaattc atattgagct ttacttgtat cttggtactc atctaccatt atgtatctaa
     9061 atctacttct gtaatatgct aacacttcat cattagcctt gaaaagttct acagttttaa
     9121 gtattaaatc atcaaagtca agtgcactat ttctttttaa acggtcttga tatagcgcat
     9181 aaatatctgc aatcttaacc attctattat ctgccatatt gatatcttta aactgctttg
     9241 gagtataaag tttatctttt gctcctgaaa ttgcacttat aactgctttt ggttcaaaca
     9301 ctttatcact taaatttaat tcttttagac agtctttaac caatgtaact tggtctgctg
     9361 aatcataaat tacaaaactt ctattgtaac caatcttatt tatatctttt cttagtatac
     9421 gaacacagca agaatggaat gtacttatcc acatatcctt agtttcagga cctatatttt
     9481 gttcaactct ctctctcatt tcatttgcag ctttgtttgt aaatgttata gctaatatat
     9541 ttggtgcttg tacaccttta tcttctataa gatatgctat tcttgttgtt aataccttag
     9601 ttttacctga accagcacca gccagtataa gtactggacc ttcagtcttt tctactgctt
     9661 ctctttgagc aggatttaat gtatctaaat tcatatttct cctcctgtta acagccataa
     9721 atatatttta atctaaaata tgaattactt caaattataa ttatgtatta tattaataga
     9781 ttatttccaa tatattacaa ttaaataaca tttttccata taatttattt cattgtttaa
     9841 taaaaaaaat aaccttatga tttggggaat cataaggcac ctttaagggg tctaggttaa
     9901 gggttattat atataaatct atttttttaa aataggttta gggcttaatt atttatttgt
     9961 attaagttct ctttccttcc aatacttata caaatcttct tctttcttaa ataagggtaa
    10021 attcatattt ctatgtactt ttactaacca tggggattct aggccagctt gtataatatt
    10081 attttcattt ataaacacat tttctgcttt tccttcatca atcaaaatcc ccttatccaa
    10141 tacatatatg taatcacata tttcatacat taaattcata tcatgactgg atattactat
    10201 ttttatatta tttttattta atccctttat tatatctaca atagacctag tacttactgg
    10261 gtctaaacca gctgtaggtt catcaagtaa tacaatttca ttttccattg ctataactga
    10321 tgctattgcc actctttttt tctgtccata gctaagaaaa tgtactggcc tgtctataaa
    10381 atctattcca ttaacagcta ctagagcttt gtttattctc tctttaattg ttttttcatc
    10441 cataccaatg tttctcattg caaaggctat atcatcatat acttttgaat aaaaaatttg
    10501 tttttctggg tcttggaaca caatacctac attttttcta aggttgtata aacttctctt
    10561 atcatatttt aacttttctt ctttaaaaag aatttctcca gatgtaggct ttaatatacc
    10621 cattaaattc ataaataatg ttgattttcc tgaaccattt gaacctatta tacctataac
    10681 atttcccttt gaaaaatcca tattaatgtt taatagtgca ttggtatttt tttcatattg
    10741 atacgttaaa ttatttattt taaacatcat tatcccctac tatgtgaaat ttaccatcat
    10801 acaattttat gtctaatgat atacacatat catcatacct tgtcataagt cttttgtaca
    10861 gcatacttcc aagaatacct aaggatttat atgaagtttt taaatttata tatccaaatc
    10921 ttagctcttg tgacttgtat atttctgaaa attcttctaa aaatatgaat ataaacctat
    10981 atattaacat tgataactcg acaaaagtgt caggtaaatg aagtttttta aaaaagaata
    11041 ttaattgatt aaaaggtgtt gtaagtatac aaaaatacac acaagtcaaa caagacatcg
    11101 ctctaaataa cacatgaata gacatgtcaa tagacgcctt tgatattcct acattaaaac
    11161 taaaaaattc aaaactatat aataaatctg ctttattaaa agatatattt acaagagtta
    11221 ttcctatact aagaaataaa aagtacattg gtattctaag taattttaaa taatttttta
    11281 aatctattcc agccacacaa acaaccaaaa tactcattaa aatcataatt ccacttaaaa
    11341 taaatatatt ttgtattacc atagaagcaa tcagaaaaat tactcctatg gctacttttt
    11401 tgtttggatt tactttactc aatctatttg tatatgcata tttatcaatt ataagcatga
    11461 ttaacttctc tttccttttt gaagacctaa tatgtatcct attacaccag cccctaaagc
    11521 tgcttgtgca gagaataata aactttctat ttctccactt ggtggctcat atggactgct
    11581 aaaccatggt ttgtaatttg gatttatctt agtaatttca ctttcagctt gaccatctgc
    11641 tcctccatat tcagcacctg agttgacaag taatgggaat ataataagag ctactactaa
    11701 taaaagtaat aatatgttag tttttgtttt agcactcatt agctttaact cctttatcat
    11761 tattttctag tatgcttttt tctccgtttt ctgtaattaa attatataca attacagtaa
    11821 gtataccttc tgctattgct attggtattt gagtcataaa gaaaattcct aaaaatttaa
    11881 ttgctgaagc cattacccca cctgatgggt ctgggaaagc cagtgctaat tgtattgaag
    11941 ttattgtata tgtggctaag tctcctattg ctgctgcaag aaatactgga atagcattat
    12001 ttccatcttt tttctttaaa gccttaaata ttaggaatga tacgattggc cctattatcg
    12061 ccattgaaaa agcattagct cctaaagtag ttattcctcc atgtgctaat aacaatgctt
    12121 ggaatattaa aactatagtt ccaagaacaa acattacgct tggtccaaac attattgctc
    12181 caagacctac accagtagga tgtgaacaac ttcctgttac tgaaggtatt tttagtgctg
    12241 ataatacaaa cacaaatgct ccacataaag ctaataatac tttcttttta gggtcttgct
    12301 ttactatttt acctattgat tttaatccga ataagaaaaa tggtataaat ataactcccc
    12361 atgctataga ccattttact ggtaagtaac cttccattat atgcattgca tttgatgtaa
    12421 ctggagttaa aatgattaac ataagtgcag ctataacccc taatttaata ttctgtttca
    12481 tcttagtatc cctctctccc tttctaataa ttaaaacata ataatacatg tctgatttat
    12541 ttaataaaat aaaaaagcct aactcgatgg ttaggcttct aattttccac aatctaaata
    12601 caaacacata aaacaaacat atctgtataa ttattataag aaactttctc catccccgaa
    12661 gaaattactt taatatttta ggcaggtctc ctgacttagc ttcatcctac tcctcttcct
    12721 tcccatgaga tataaaaaat atcatcatag tggctaacaa aagtttcgtc tgcatcacag
    12781 tagcgggggc tgtaaaggaa tttaaccttt ttccctatta atcttgctta aagaacctat
    12841 aatattatat atttaatttt taaattcttc ttaaattatt ttctatataa atcattgtat
    12901 accttttctg tgaaaatttc tacatttttt ataaatttta ttcattttta tatttttatg
    12961 tatataaatt cttttttgta agtttattaa tttctaatta tcttctttaa atacattgaa
    13021 actacatcag aaaatctagt tatatctctt gaatatataa aatcatttcc atatattaat
    13081 ctttcagctt caagttctga ttcttttcct gtaaatactc ctaatactaa tatattttgc
    13141 tttctagctt ttctcacttc attggctgta tctctcaaac caactatacc cctataagcc
    13201 ttttctcctc ttaatgttct ctcactactt tttcctatct ttacatcatt tggtcttcca
    13261 tcactgagaa ctatcaggat tttattttct tcatctctat ttattagacc actacatata
    13321 gattttattg ccaaaccatc tctattatta ccagcacaaa aatattcaaa tatattttca
    13381 ctatttttta tactatcatc ataatcttta aatcttttta atattgtata gtctaaaaaa
    13441 ctagaaaatc ccatcactct atttggtatg ccaacttctg ttagagcatt tgcaattatg
    13501 taagcttgaa ttgccacatt tccctgattt ctactttgag agccacttgc atccaataat
    13561 atatcaataa cgtatttccc tttttcattt tctatatctt tataaaatat tttattatta
    13621 ttacttctac caactctcca agctctattg gctaatatag taccacaatc agaatatact
    13681 ctacttttag cattttcttc tattaaaatt cttgatagac tttcttttaa tctctttatt
    13741 tgctgtctat acattctagc atgttctcta aattttccta aattattttc tttttgtctt
    13801 gttacatatt ttagttgaaa tacattatta cactcacttc taagaactcc atctgtaaag
    13861 tgtattctac aaccttcatg aacatttcta caattttgtg tctcaatttt tttaatttca
    13921 cctttactca aataagtttt tccataataa tgttctattt ttgaatatat cttatttgca
    13981 gtgtcttcat caacatatat aactcggtct gctgaattgc tacatttaga atcatcaaaa
    14041 tcccctacac cttctacaag catggatgaa gatattgaat ctatatcact ttcaataata
    14101 ttttcttctt catcactata aagttcttca tacatgaaat cagcaaatgt atcaaaattt
    14161 acttctacac tttctacatt attttcatca ataagactat tttcttctcc atttaatatg
    14221 tattcaaaat aagttaaata tataacatct aatgctttta aaatctccat aatatcttga
    14281 ttggtatcta tatttcttat atcattaact attcttctag tcatactatc taatgctggg
    14341 tgcttgtcca tactataaag tacaaatgtg tatttaattt tatccataat attatcattg
    14401 tgtattttgg taaaacgtga aacaatatct ttataagcat ttcttcttat gtcttctatc
    14461 cctggcctat ctttaatgac cttttcttca actattgtat ttaatataac ttgaattaga
    14521 cccagtataa tatctttgtt gtatcctttt cttattctat ttgtaagata ttttttaact
    14581 atatcccaat ctacatactt tcttctagca cctgcaatta ttgcaaaata tagacctatt
    14641 tcttttgaag agtaatcttt ttctgatata tctatacttt cattgtaatc accagctatt
    14701 gtccatgata agttattagc tctattttca aattcataat catcatatat ccatttcata
    14761 atctcaccta tattaaatat gacttattgg aaacacatct atactctccc atttattagg
    14821 tattctagtt ttaattacat ctccaaccat ttctttctca tatacatcaa aagtctttcc
    14881 tgtaagtccc atattaattg caagagttgg ttttaatcct cttcttatag tcttaagaga
    14941 tgccataaga ccacgtaaat caatagcttt actagatatc tctccatttt gagacttcaa
    15001 ttgtaaatct aaaaatattc ctgcaaagtg tattagtttt tcttcatcag catctgaaaa
    15061 ttcatttttt aaaatcatca ttaacttatc ttcttctata ggaggaatat ctattaccat
    15121 aaatctagat accagtgctt cattaagttc ttttgttcct gcatattcat aattcatagt
    15181 cccaataaat cttgttgctg gatgtagatt gactctctca tacccaggta catcaattat
    15241 tcttctatag tctaaagctg aatgtaccac aactatagca tcattttttg ccatattaat
    15301 ttcatcaaac accccaaaac ctccattaat agcacactca taaactgagc ctcttctaag
    15361 tttaacttca ttgtctataa atgtatctgt acctataagt gttgaactgt ctgtatttat
    15421 atgaaatgat gtattccact gaggtctatt aaatatttcc cctagattat cagcaagtaa
    15481 gttttttccc gttgcctttg gtcccgataa taatatattt tcttcttcta aaatagctgc
    15541 tatacacata gacaagatat ctttaccata aaaataagtt ttagactttg ttactctgta
    15601 ttctaaatct ttttctaatc cataataatt tctaaaatac agtacatctt caataagttt
    15661 ttcatctacc ccttgcaccc ttagattatc tattatatcc atatttttac cccttttata
    15721 taaatagtat ttgtttcatt tcttatcacc attttagcat aaaaggatat aagctaaaat
    15781 tgatttttta atctccccca ttttaagtaa aaccatgcac cattttatca ctacaaaatt
    15841 aagagtacta cttactgata tttcttgatt ttattcgtct atacgtatat aatatatact
    15901 gataaattat gaggaaagga tgattgaaat atggaatata tgtcttgccc agaagtagca
    15961 aaaaaatggg gtatttctga aagaagagta caaaaactat gtgaagaaag tcgcatacca
    16021 ggagtttcaa aactcgggta tatgtggctg ataccaaaga acgcagaaaa gcctgttgat
    16081 ggtagaacaa aaagaagaaa ggaagtacaa tatgaatagc gttttgatta tagatgatga
    16141 caaagaactt tgtgctctta tgaaaaaatg tgttgagcaa gaaaatttat ctgctattac
    16201 tgcacatggt ggtgcagaag gtctacattt agtcgataaa aatagacaca cactctctct
    16261 tgtaattttg gacataatga tgccagatat agacggtttt caagttctga aaaaaattag
    16321 agaaacaagt aatattccag taattatgct tactgctaaa aatgacgagg atgataaagt
    16381 ttccggacta cgtttaggtg ctgacgatta cctaacaaaa ccgttcagca taaacgaact
    16441 tatggctcgt gtcaattctc ttattcgtcg gtatactatg ctaaaccctg cttttataac
    16501 agacacagat ttcataataa taaatggcat gattattgac aagacaaacc gaattgtttc
    16561 tgtcaataat attcctgttc aacttacaag caaagaattt gatttacttg cttttctggc
    16621 ttctaataag ggacgggtgt ttaccaaaaa acagatttat acacaagtat gggaagaaga
    16681 atatgctttt gacgatagta acatcatgtc tttcatcagt aaattgagaa aaaagattga
    16741 accagacccc aaccatccat tttatatttt gacagttcgt ggtgtcggtt atcgttttaa
    16801 taaggaggct taacatgaat acaagtgtct atctgctttt gatattggct cttagcctga
    16861 ttattatagc gtaccttgtt tctgtcctgc tacgtgtccg agtacaactt acacttataa
    16921 aagatgcttt agaggatata aaaaatggaa accttaatcg acgtatttta acagatgaaa
    16981 acgacattac aaaacaaatt tgctatgata ttaacgaaat agcaatcaat agccaatttc
    17041 aacttattca gcaaaaacaa tcagaacaag cctacaaaca gctaatgaca agtctctccc
    17101 atgatgtaaa aactccactt gcttctttgg tcggttattt ggaagcagta gaaagtaaaa
    17161 ttgttgtagg agaggaaaaa gacgagtata tccatgttgc gtctaataag gctcattact
    17221 taaagaattt tgtagaaaat ctatttgaat gggtaaaatt ggattctaag gaacaagttt
    17281 ttcattttga tatttttgac ttgaatgaat tatcccgtaa tattatatct gattggatac
    17341 ctgttttaga aagcagtcat tttgaatatg aatttgatat accagaaata gagtacttct
    17401 tacgtataga cgcaaatgca tatacccgta tcattaataa cctattacaa aatattatta
    17461 cccatagtag tggaaacaaa atgacattga gaatttttga aaacaaagag caagctcaaa
    17521 ttataataac agataatggg aaaggtatat cttcagacaa tctcccacat atttttgaaa
    17581 ggttgtacca atgcgaccat tcacgagctt caaagggaaa tggtttaggc ttggcgattg
    17641 caaaggaact tattaacgct cataagggaa atattaccgc caacagcact cccggtatgg
    17701 gaacagaatt tacaatattg cttcctaaag ccctgtaaaa gtacgaggct ttcttactct
    17761 aaaacaagat aaaagcaaga ttatggcaag gttttggcaa ggttcatgtt ttataattct
    17821 aattgtagtt gattttgacg ttgtatcaac tatcttttgt agaaacaaat ttattaaaag
    17881 tgaggaaatt atatatgaat gattttgtga ttgaaacaaa gcaacttaca aaaatttatg
    17941 ggaatcaaac agtagttgac aaagtcaatc tccatgtaaa aaaaggccga atatatggtc
    18001 tgttaggacg caacggagct gggaaaacca caattatgaa aatgatttta ggattgactt
    18061 caatcacgta tggcgaggta gatgtatttg gagagaatat taagggacgt gaaaaacaag
    18121 tatatccccg tatcggtgca attatcgaaa cgccaggatt ttatcctaat ctgacaggaa
    18181 cggagaactt ggagattttt gcaaaactgc gtggtacagc cgcccctaat tctgtaaaaa
    18241 gagcattgga aattgtaggc ttaccttata aaaataaaaa gctgtttagt aaatattcac
    18301 ttggcatgaa acagcgactt ggtattgcca acgctatcct gcatgaccca gaactgttag
    18361 ttttagatga gccaaccaat ggtcttgacc ctattggtat tgcggagatg agaaagttta
    18421 ttagggactt gagcgttgag catggaaaga caattcttat ttccagtcat attctttcag
    18481 aaatctcatt gttggctaat gatattggaa ttatcgacca cggtgttctt ttggaagaaa
    18541 gtagtatgag tgaactagaa aagaaaaaca gtaaatatat cctgctacaa gtttcagata
    18601 ttccgaagac atcacttatt ttagagcgtc aatttaacac gaaggattat tccgttcaag
    18661 atgactacac gttacacctt tataacacta atctggatat gggtgaaatc aataaagcac
    18721 ttgtaatgca gaatgtaact gttattagtt ctcaactttg taatgatact ttagaggact
    18781 actttaaaaa aatcacagga ggagagggca ttgcttaaac ttattcaaac agaatttctt
    18841 aaactgcgtc gtaggaaact tatttggctg atgttgttgt ctgctctcat tatgccgttt
    18901 ttcgcactac tatacttcaa ttattttggt aaaacaggtg ttgagccaat aaagttttat
    18961 aaatggtctg catttggtta tacactttgg attattttgc ctgttgtttt gggtatattt
    19021 tgcaccatgc ttatacacga agaaaaccag tatgatatgc tcaaacagct ttggattgta
    19081 cctattagta aaatgggata cttttttagt aaatttttcg ttgttttgat ttactctatt
    19141 tgttttatgc tgattacagc cgttgcttct gtgttattta gtgtactttc tggatatgtc
    19201 gtatttagct gggcaagcat tttatatttg ttgaaaaaat gtttagaaat tggtgtaatc
    19261 actgcttttg taatgttgcc gattttggca atcgctacat ctcaaaaagg atacattctc
    19321 ccaatttgta tcacattggt atatgccttt tccggttttg ttataatgac aataaatatg
    19381 tatttacacc cattatccag tatgggagtt attatcatga gaaataaaga cattccaggt
    19441 cttatatttt cacaggaaat taatgtccca ttagcatttc tttgtatttg tatttggagt
    19501 attgtatcag tattgtttgc aaatattgca ctaggaagaa gaaagtgagg tgtagataat
    19561 gtggaaatta ctttgggctg aatgtcaaaa aattcgtcgt tcaaaaattg tttggattac
    19621 agtttttgca tccattatga tagcagtcat agtttttgca ggggggcagg atgtatataa
    19681 tgacccagat ttacattatg gcttaaagag cgtttatgac ggttcacggt atatagacaa
    19741 tgcaggttgg tatatggacg cagtacaacc ttggtcaact ttttttgttc ttcctgctgt
    19801 cattgcccta ttaggaagct atattatttg tcgtgaagaa gaggaggaca ctattaaatc
    19861 cctgcgtctt attcccataa atgaaacaaa tttaaccata gcaaaaatga ttattacttt
    19921 tatattcagt atacttcttt atttgttact ctttactata acatttttga ctgaatccgt
    19981 tttacatttt tccgatttat cgacaaaatt ggttttaagt tgcatgaaag agtattttct
    20041 tgatggcata ggtgtattct ttgcaatttc tcccattatt gccttggtat cgcgcatgaa
    20101 aaaaggatat tggcttgcat tagtattcac agaagtttat tctattgctg gactatttgc
    20161 gggtatgtca aatgtcttac aaaccttttt tcctattgcg gcaatattta atatttctgg
    20221 atactatata actactggag aaaaaattat ggggagtatc atgagtttat tactttgtgc
    20281 ctgcctttct gcatttatac ttaaagggct aaaacacaat gaaaaaaatt gaaataggta
    20341 tatcaaaatg aaaaagataa aaaaactgat tattctaatt gtattcttgt ttctttttgg
    20401 catgttacac tgttatactg aatggaaatt caacaataac ccacctaaag gggtaataga
    20461 aagaataaat gagtggactg ataagattgg actggattag taacttatgt taattatagt
    20521 gaatgtaata ttagcaagtt attgtttcgt attttaatac tataacttta aatatttggt
    20581 tttaatcttc caaacgaata taaaaaaact gtcacagagg caacatattt ttgaatattt
    20641 ataaagtggt agttttgatt ttcaaagcta ccgccttttc ttctatataa gcaaacttat
    20701 cctcaacaaa gtgtaaaaca tggtgcattt taagaaaaaa gtaccacaga cacaagcaat
    20761 aaaagaaacg ccgagaacct acaaaaacgt agtgcttatg cagatttacg acgccttcta
    20821 ttttctcaac cgtcttaatg accttgtaca aaagaaattt ttctaatatt ttttataatc
    20881 ttatcttgtg atgtttttta tgtataaatg acttaataac aaatccaata aaaattatgg
    20941 atattggtat aattagaacg aggaatttat aatcattata atgtgacatt attcttaccc
    21001 aactctcaga aaaaatatat cctatactga ttaatgaagt attccatatg gttattccca
    21061 cgatagatga tattacaaaa gttataatat tttgacctgc tatacctgct ataaaagata
    21121 tgtatgttct acataaaggg attaatctac atacacaaac agaaatagaa gagtatttat
    21181 taaaataatc ttgagatgca aatattcctt tctttgcctt tggacatatc tctattattt
    21241 tatttatgat agatttacct ccccaatttc ccactgtata acaaaatatc gaaccaagta
    21301 tacctgcaat tatacttaaa attaaaattg tcagaaatcc aaaatgattt cttgcagcaa
    21361 ttgctccaca taaaggtaaa acaacttcgc taggtaatgg aaaacaagca tactcaatca
    21421 taattaatac aaatacagag attaatccat attgtaaaat aaaactattg attacagaca
    21481 cttacttatc tatctccttt cttatttaaa ggttttaagg gtacatgttc taaggattct
    21541 caccctatat ttaaagaatc aatctcttta aactattata tgtatttaca caaagcattt
    21601 ataacatact ttaaaaatag taccttaaaa taagaaactt aataaataaa aaaagattac
    21661 gtggctacgt cctactctcc caggcagttt cccaccaagt accatcagcg ctagagagct
    21721 taacttctgt gttcggaatg ggaacaggtg tatcctctct gctattgtaa ccacataatc
    21781 tttatgctta atatttc
//
LOCUS       DAGQVA010000069        21701 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.069, whole genome shotgun sequence.
ACCESSION   DAGQVA010000069 DAGQVA010000000
VERSION     DAGQVA010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21701
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.069"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(253..540)
                     /locus_tag="MIV85_002857"
     CDS             complement(253..540)
                     /locus_tag="MIV85_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2962185.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            complement(553..2472)
                     /locus_tag="MIV85_002858"
     CDS             complement(553..2472)
                     /locus_tag="MIV85_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2962186.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQPYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSIIELINKQN"
     gene            complement(2816..3340)
                     /locus_tag="MIV85_002859"
     CDS             complement(2816..3340)
                     /locus_tag="MIV85_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962187.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            complement(3344..3841)
                     /gene="coaD"
                     /locus_tag="MIV85_002860"
     CDS             complement(3344..3841)
                     /gene="coaD"
                     /locus_tag="MIV85_002860"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBY2962188.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            complement(3843..4397)
                     /gene="rsmD"
                     /locus_tag="MIV85_002861"
     CDS             complement(3843..4397)
                     /gene="rsmD"
                     /locus_tag="MIV85_002861"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBY2962189.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            complement(4456..6513)
                     /gene="recG"
                     /locus_tag="MIV85_002862"
     CDS             complement(4456..6513)
                     /gene="recG"
                     /locus_tag="MIV85_002862"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBY2962190.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            complement(6594..8237)
                     /locus_tag="MIV85_002863"
     CDS             complement(6594..8237)
                     /locus_tag="MIV85_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBY2962191.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            complement(8256..8606)
                     /locus_tag="MIV85_002864"
     CDS             complement(8256..8606)
                     /locus_tag="MIV85_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBY2962192.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            8967..9155
                     /locus_tag="MIV85_002865"
     CDS             8967..9155
                     /locus_tag="MIV85_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBY2962193.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(9315..9467)
                     /locus_tag="MIV85_002866"
     CDS             complement(9315..9467)
                     /locus_tag="MIV85_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBY2962194.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(9565..10041)
                     /locus_tag="MIV85_002867"
     CDS             complement(9565..10041)
                     /locus_tag="MIV85_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBY2962195.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            10260..11021
                     /locus_tag="MIV85_002868"
     CDS             10260..11021
                     /locus_tag="MIV85_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2962196.1"
                     /translation="MEYTVQKLSKLACISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(11281..13209)
                     /locus_tag="MIV85_002869"
     CDS             complement(11281..13209)
                     /locus_tag="MIV85_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBY2962197.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            13443..13895
                     /locus_tag="MIV85_002870"
     CDS             13443..13895
                     /locus_tag="MIV85_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2962198.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTNEVKNASDASHLVKYITNKMKEE"
     gene            13898..14206
                     /locus_tag="MIV85_002871"
     CDS             13898..14206
                     /locus_tag="MIV85_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBY2962199.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            14320..15426
                     /locus_tag="MIV85_002872"
     CDS             14320..15426
                     /locus_tag="MIV85_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBY2962200.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            15501..18179
                     /gene="mngB"
                     /locus_tag="MIV85_002873"
     CDS             15501..18179
                     /gene="mngB"
                     /locus_tag="MIV85_002873"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBY2962201.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(18496..20829)
                     /locus_tag="MIV85_002874"
     CDS             complement(18496..20829)
                     /locus_tag="MIV85_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2962202.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKAVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(20804..21520)
                     /locus_tag="MIV85_002875"
     CDS             complement(20804..21520)
                     /locus_tag="MIV85_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962203.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         7433 a         3420 c         2574 g         8274 t
ORIGIN      
        1 agtagtattg gataggttct atcctatctc tacatatagg tttccctata tgctgactat
       61 tttagctact aactcatgac taaggtcacg agtgtgcgta gctatttttt aatcaagcat
      121 tatatttttt agtgataggt caactgttta agttttctac cactaaatcc ctcctctctt
      181 tcttactatt tttgaactta gtaagttttt attttattct gattaactta aatttacttt
      241 ttaaaactta tactatttct tatcattttt atcacttaaa aaagtttgaa caacttctgt
      301 gacttctgct aaatccatgt actttttaac tggatataca tctacattac aagttccttt
      361 taattcattt aacaattctt gacttgtgaa tatacagtca caatcagcac ctctagctga
      421 atttatatct gtattttcta cttcacattc tatacctaac tgctttagag ccttttggat
      481 tgtcattttt aataccattg atgaacctac accaaaacca catactgcta atatcttcat
      541 ttttcattcc ccctaatttt gcttatttat aagttctatt attgaacttt tatcaccatt
      601 aattattagt tttacatttt cttcctcgta catcatctct gatagtgatg ctaatgctct
      661 aatgtgagta gtgttatcta cagcagctaa taccataaat atatttactg gttttcctaa
      721 taaatcaact tcatcttcta ctattagtaa agacatagca agcttgttta ctccttcttt
      781 agaacttgca tgtggtagag caaatctatc agctaaaaca atatatggtc catatttctc
      841 aactgacttt atcatatttt ctatatataa ctcttctata gagttatctt ctaacaatgg
      901 ctttgaggct atttttattg cttctttcca atctctaaca ttttttatta tattgaccct
      961 ttctgcatta attaattcct ttaacattgg ttgatacatc tctccttcat ctatcttgtg
     1021 tattatgttt aataaatcag cttttagtgc ttcttcatta ttgataactc cattttttct
     1081 tatagcttgt attattaatt caagattgaa atacttctcg ttttctttta cacttattag
     1141 tttgttcata agtaattgaa catctgatga tgttaaaaga ggatttacaa caattacgtt
     1201 gtttacattt tgtatatcta tagttgtaat tatgtaatcg tagtatacat ttacttcttt
     1261 tagttgctta atggatacta tacctactat ttctatggtt ggtatgtatt tatatggttg
     1321 tatttccaaa ctctttgata ccataagacc attaggacaa actagtaaga ctttatttct
     1381 tcttagacca ttatccctag accctcttaa atatcctcca aaatacgctg ctataaatcc
     1441 tatttcttct tctcttatcc cctcaaatac aggaaactct tcttcattct ctataattga
     1501 ttttataatt ttataaagtg actcatgttt atacttagtc tcatctaaca ttggatttct
     1561 aataggaaac ttaaatcgta ttctgttgta agaagagtgg aggtgcctta aaatattttt
     1621 cttaaactca tgcttacttt ctaattttat tgctgtattt acttcaaact tatctataag
     1681 tttatctaca tattcttcaa caacatcttc cttaacttca ctatttaagc tgggaagtga
     1741 acttatgtaa gtgcatatat aggcttgttc attttcatta gcttcttcac ataaaagttc
     1801 tttacaatta ctaaagtaac taattttttt agcttcattt agatatttat atgagtataa
     1861 tgttttccca tctcttatcc ttttatttag aaattccaca aacttagtta gatttaataa
     1921 agaataatca gtaagtttta tatgtccttt tgtatcgaaa ctacttactt cctcacttat
     1981 agaattaatt tccagtacat tttcttgaac aattatcaga aacagctctc taataacgta
     2041 ttcatcacct ataattttgt actttccctt atactctaat cttaacccca ttgtttgaag
     2101 gtattttttt acatcagtta ttgtttgtac tactgtgttt tttgaaagta acatttcatt
     2161 tgttagtttt tctattgata ttttttcgcc aagtaatatc ttgtttaata taaaagtttt
     2221 tctgtaatca ctatctaaaa atttatcttc ttcagttgaa attattttcc ttgcatcaca
     2281 taaattacct tcaaatataa atttgtgttt tacatttttt atattaccac tttttcctag
     2341 ttgttcattt atagctagaa tatcgtaata aatagttctc tttgaaacat taaacttttc
     2401 ttgtagttct tgtgatgtta cattgttatt tttaataata aaatctaata tttttttagc
     2461 cctttccttc atactacctc cttaatttta ttatctatat tttctacatg tagtgccata
     2521 ccaaataatt gcacatgatt tagtattatt ttataatttt gcacagtcta actctaatct
     2581 aaaagaagac agtggtaaaa ttattaaaaa aatttgaaaa taacctatat tatttataca
     2641 aataaataag ttgatttcaa caaataaaag attaaactac attataatat caaaataaga
     2701 tataagtaat ctaaaaagca caattatata acaaaaaatt gctatattaa aagagagcta
     2761 tcacacataa attggaattt tttgtgtgat agctccattt ttatttattt aaaatttatt
     2821 ttttaggtct aagttcagct ttatctcttt ttacttcttc taatatttct cttaaattat
     2881 actcaacact agaaagcaca tcctctgcat attcaattga cccaattctt atctcattgg
     2941 ctattctctc agctctatca actatatctt ttgctctttg gtctgcttga acaacaggtt
     3001 cactggattc tacatatgcc tttactacat cttcagaatt tttctttaat tcctctatat
     3061 tatcttgata ttcttgttgt attctctcag cttctttttt cgcttgttca actatatttg
     3121 tagcatcttg cttagcttga cttattattt tatttctttc tttattaatc catactgcct
     3181 gtgttacttc ttctggtatt aaagttctta tatcattaat tattgctaaa acctcatctt
     3241 tatccactgt gcatttatgt gagaaaggga ttgtagaagc acttctaaat atctcctcta
     3301 actgctcaaa tagttcaatc atttctaaat ctatcttcat atatcaatta cccccactag
     3361 tttttttctt taattcttcc aaaacaatct ttggaaccaa attttttata tcagcatcaa
     3421 agagcaaaac ctcttttatt aaagatgaac ttataaatga atattttgta caacttggta
     3481 aaattatagt ctctatatct ggattaagct ctctattcat atgcgccatc tgaagttcat
     3541 aatcaacatc agcaccactt ctcacacctc taactaatgc tccaatccca ttttcctgac
     3601 agtaatttat taataaacca tcaaaagtca caacttttat attatttaaa tggcttgtac
     3661 ttttttctat aagttttact ctttcatcaa agctaaatag acccttttta ttaggattat
     3721 ttaatactcc tatttgtaat tcgtcaaata acttcgaagc cctgcaaata atatctaaat
     3781 gtccattagt aattgggtca aaacttcctg caaatatagc ttttctaggt ttattttcca
     3841 tattatgcct ccatcttata aaaagttaat gtagtatttc catatttctt atctctagtt
     3901 ttctccaatt tacatatctt atctggaaat aaatcattcg tatcatgttc tacaactatt
     3961 attccatctt cgttcaatag attagaatta tcaatttttt caatagcttc tataaacata
     4021 tttttataat acggagggtc cataaaaatt atgtcaaatt tactattttg taatttaagt
     4081 ttatctattg cagtcttaaa atcaaggttt aaaataatac tttcactttc aactcttgcc
     4141 ttttttatat tggacttaac aatatctatg ctttccttac tgatatctac aaaagtacat
     4201 gacttggcac ccctagataa gcactctatt cctaaagaac cagtcccagc aaataaatcc
     4261 agaacttcac tttccattat atatgaattt atcatattaa atagagactc ttttactcta
     4321 tctgtagttg gccttacatc ttcatttttt ggagtattta gttttaatcc tctcgctttt
     4381 cctgaaatta ctctcaatat gacaatctcc cttcagcaca ttattacatt agtaatattt
     4441 taacacaatt taaaattaat ttaatgaaat ttctttcaat gtatctttaa atttatctat
     4501 aatttctttt ttgagtgcca tgttttcttt taattgtaga ttattatctt cacccaatat
     4561 atatcgagct tcttgctgtg ctaacttcag tatttttata tgcttaaata agtttgctac
     4621 cttaagttct ggaagaccat gctgccttgt cccaaaaaat tccccaggtc ctcttatttc
     4681 taaatccttc tctgaaatct taaaaccatc attggtctct tccattatag ccattctttg
     4741 tctacataca tctgttttag aatcataaat tagtacacaa tacgatttat gactacctct
     4801 tccaactcgc cctctaagct gatgtaattg tgcaagtcca aatctttctg cattttctat
     4861 tatcattaat gttgcatttg gcacattgac accaacttct attactgttg ttgaaactaa
     4921 aatatctatt tctttatctt taaaaagtct cattacttca tctttttcac ttgacttcat
     4981 tttaccatga agcaacccaa gccttaagtc gtgaaaatat tccgctctta actcctcaac
     5041 aagttcaact gctgatttgg cttctatggc ttcactttct tctaccaagg gacatacaat
     5101 gtacacttgt cttcctgatt caacctctct tcttacaagg ttattatatg ctctatctcg
     5161 cttacttttt tcaatagcaa ttgtttctat tggctgtctt cctggaggaa gttcatctat
     5221 aatagaaata tctaaatctc catagagtat aagtgctaaa gttcttggta ttggtgttgc
     5281 tgtcattact aatatatcag gatttgctcc tttcaatgaa agtttgctcc tttgcataac
     5341 accaaatcta tgttgttcat ctgttataac taaaccaata ttattaaatt caaccttatc
     5401 ttcaattagt gcatgtgtac ctattaatat atcaatctca ttattcttta tttgttccaa
     5461 tactgtatcc ttttgttttt ttgtaagact acctattaat agacctacat ttattccaaa
     5521 atcttttaga gactcagtaa gtgaaatata atgttgccct gctaatatct ctgtaggtgc
     5581 catcaaagcg ccctgataac catttaaaac acaatttgca agtgctaaga gagctactac
     5641 tgttttacca ctccctacat caccttgtac caatctattc attattttct ctaaattcat
     5701 atcttgtata atttcatcta atgccctgtt ttgagcttta gtcagtttaa atggtaaagc
     5761 acttattatt ttttttaagt ctttacttgt ttcaaacttt attccatctt ctttatttct
     5821 gccactttta aatacaaaca accctagttg tagtataagt aattcttcaa atacaattct
     5881 atataaagct atttttaatg attccttact acttggtgaa tgtatgtttc taactgcaaa
     5941 atctatacta catagcctat atttttctat aattctttgt ggcatatatt cttgtataat
     6001 taattcttta tcttcaagta ctgttctaat tatactcata atttctttat ttgtaacacc
     6061 gtatgtaagc tggtacacag gcataaatct acatgtattc ttaggtgaat tagtaagata
     6121 ttctaattca catgatgtaa gttctaagtt attaaatttt ttcttaacct tcccaaaaac
     6181 taatattgaa tctcctggac gaaaagtatt ttttatataa ctcttattaa aaaacactaa
     6241 tttagccgag cctgtctcat cttttacatc aatctttgtt aaagtcatac cttcttttgg
     6301 gctaaatgta tttatacttg atattactgc ttttatcgta actttctcac catcttctaa
     6361 ttgtgctatt ttctttagat tatttctatc ttcaaattgt cttggaaaat aatacaatag
     6421 gtcttttagt gtaaatatac ccagtttatt taatttatct gcttttttag gtcctattcc
     6481 cttaacatat tgaacatctt tatataaatc caacaaatat atcacctact acacaaaaat
     6541 cctgtacaac caattttata aaagctactt ggtcatacag gttcttataa tcattattca
     6601 actgaaatta agtaataata aagaggttgt cctccataat ataactctac atctacatct
     6661 tcaaactttt cttctaaaga agtacgtagt tcatttgctt gagattctgt aacatcttca
     6721 ccaaagaata atgttattat agcagtatct tcatcaacca acttttcaat aaggtttgat
     6781 gttacttcat ccacataatc tcctgctgat aataaattcc cttctgcaat tccaattata
     6841 ttaccttctt taacatcaat ttcgttcatc actgtatccc taacagcaaa agttacttga
     6901 cctgatttaa ctgagtttaa agcattcatc atagcttctt tattttcatc ttcgcttaat
     6961 tctccattaa aagttactaa tgcagcaaat ccttgaggcg tattttttgt aggtataact
     7021 attatatttt tatcactcaa ttcttttgcc tgattagcag ccattattat attgctgtta
     7081 tttgggaaaa taaatatatt tttagcattt atatgcttta tagcattcat aaaatcttca
     7141 gtacttggat tcatagtttg accaccttct attatatggt caactccgaa atctttaaat
     7201 atatttgcca aaccttcacc catagaagta gctataaacc caaactcttt ttcttcttct
     7261 aaaggttcac tatcattttc tttcttttct tctacatcca gtaatgtatt ttcatgttgt
     7321 aacttcatat tttctatttt tatagttaat aattgaccgt actttagagc ttcttgaagt
     7381 acatttcctg ggtcattagt gtgtacatgt acctttatga ctccatcatc tccaactact
     7441 gctaggctat caccataagc catcattatg tctcttattt tagtatcttc taccttagaa
     7501 ctttctaaaa taaattctgt acaatagcaa tattttatat catctgtgct agtagtactc
     7561 tttgcaaaat ccatacttgt tgaaatatta gtatctaggt caacattttt tatttctatg
     7621 ttatcgcctt ttatagaagc taacattcct tcatatataa gtacaagacc ctttccacca
     7681 gagtcaacca caccagcttc ttttagattc tttagaaggt ctggagttct ttctaatgaa
     7741 gaatttgatt ccttcacaag catacttaaa aactttacta catctttctc ttttttcgca
     7801 gtttttattg caaactctcc actttctcta actacagtaa gtatagttcc ttcaattggt
     7861 tttattacag ctttatatgc tgtgtctgaa ccatttttaa aagcttttgc taaatcttct
     7921 gttgataatt tactttttcc ttctatagat ttagctatac ctctgattat ttgtgaaagt
     7981 ataactcctg agtttcctct agctcccatt aaagaacctt tagataatgc ttttccgata
     8041 tctgatatat tatcattttc aacttttgct aattctttta aggcataaga tattgttaat
     8101 gacatattag ttcctgtatc tccatctggt acagggaata catttaactt gtcaactaac
     8161 tctttattgt tttggagatt gtttgcacct gaaataaaca tctcccttaa ccttttacca
     8221 tctatatatt gaatcatttg tttcctccta tgaaattact taactcttat tccttgtaca
     8281 ttaatatcaa ttctagtaac tcttacgcca gtcatttttt caactacata ttttactcta
     8341 tctattatat tattggcaac agtagatata tttgtaccat attgtattat aacataaagt
     8401 tcgattgcta tggcatcttc ttctacttcc tcaactctta cacctttagt tgcgttctcg
     8461 ccttttaata gctctactat tcctttagac ttatatgcta aacctactaa gccataactt
     8521 tccattgcag ctctatatac gacttgagct attacttgat tatctatttc tatatttcca
     8581 tattgattcg ttacctttgc actcatggtt gaccccctta agcttatttt tattaaaaac
     8641 atttcttaat ttatttttta ctatttttac ttatttatta tataaaatta taatcatatc
     8701 atactataaa tatggtataa tttaaaccta gaaaagtttt tggataaaat ttcttctata
     8761 gtatatatat tcaaagaaaa ataataatta ttttccaaat atatttactt tatataaaat
     8821 tatatatata attttatatg ataataagaa attcttcaat atgtgtaagg caaatatata
     8881 tttctattgc aaatttttgt tatttatgat aatataaata tgtttttagt ctttaaatag
     8941 ttatcatttt aaggaggtgt gcgtagatgg caaaagtatg tagcgtatgt ggtaaaggta
     9001 aggtttctgg aaaccaagta tcacactcaa ataaacataa taaaagaaca tggtcagcta
     9061 acttaagaag cgtaagagcg attatagatg gagctcctaa gagagtaaaa gtttgtacta
     9121 gatgtttacg ttctggtaaa attgaaagag cttagtaacc acgtttaaaa gcctacttcc
     9181 gtaagtaggc tttttaattt aatcattttt actctttctc ataaatttta ggattatact
     9241 tgaaatccat tttggtaatt ttattgttac tactttcatc aatactcacc ccacacttta
     9301 tagttaaaac tattttaaca aaaaaataat aatgctccac atccaataag tattaatgcg
     9361 gtaagtgctg accaaatcca gccaggaagc aacattgaca gaattacagc cattcctgtt
     9421 gctagacaaa gtattcctag caatacctta gacttgttat ttctcatgga acacctccac
     9481 atagaacctg tatctataaa tattttcata ttcaagttta tgcgacagtt ttccatttta
     9541 gaccaataaa cacattatgt aattttaatt tttcatacta gaattattac tgaactccga
     9601 tatagattct acaatatcca aaattccttt ttttctactt aacctttcag gtccactata
     9661 taaaacaact ggtataactt taggaagttt aaaattttta tcttctattt cttcaaggct
     9721 ttttttcata ataaaacttt tccaaatttg ttctctatac gatttcaatc ttgggacaat
     9781 ttcagtatcc atttctgttt gaaattctaa cactatataa tgtgatactt tgccactttt
     9841 agaaaatacc ttataaatta tatcaacttc ttttccttta tattcacata taaaagatgt
     9901 ttctaactct atatttttaa gagttaattc ttttgctatt gagacacttg taaaattttg
     9961 aatcaaactt aaaaaacttt ctttatctga atacattctt ctgtactctt ctcgtttttc
    10021 attgcttctt tttaaattca tacagttcct cctagactat agaccctcta ttttttagta
    10081 aagatagtct ataaatttta ttttttaatt ttcattagtg agtattgaca gttgtgtgta
    10141 aaatatccag taaagatatt tttttatatt tttattaaaa gatataaatt tttatatttt
    10201 aatgtattga catttacgtt gcgtaaaagt gtatatttaa tttataggag gtactactta
    10261 tggaatatac agttcaaaaa ttaagtaaac tagcttgtat aagtactaga acacttagat
    10321 attatgatga aataggtctt cttaaaccac ttaaaataaa ttcttcaggt tatcgtatat
    10381 atggtcaaaa tgaagttaat aaacttcaac aaatactttt ttatagagaa ttaggaatta
    10441 acttagaaaa tataaaaaac attataaatt caccaaactt cgatagttta agtgcgttaa
    10501 aagaacacca taataaatta ctagccaaaa gaaagcaaat tgatttacta atagaaaatg
    10561 taactaaaac tatagctctg aaggagggaa aatacactat gacagatata gaaaaatttg
    10621 aaggttttaa agaaaagatg attgatgaaa atgaaaaaaa ttatggaact gaaattagag
    10681 agaaatatgg taaagatatt atagatacat caaataaaaa acttaaaaat atgtctaagc
    10741 aagattatga aaattggcaa aacctaaata tcgaaataat tagtaaactt aaaaaagctt
    10801 ttaaaactgg tgatgcctct agtgaactgg ctcaggaagt tgcaaaatta catcataaat
    10861 ggttgagtta cacttggaac acatactcta aagaagctca ttcctctcta gcacagatgt
    10921 atgtatatga tgaacgtttt acatcatatt atgatagaga acaacctgga ttagctaagt
    10981 ttttaaggga tgctatagta atatatacaa gagataaata atataaaata ataaaggtgg
    11041 tgtctcaaaa tgaacttttt agttcatgag acactctttt ttgtatgaaa tcagatatat
    11101 ttttatcatt ttatcaatga aaaacaggtt tctctctcta ttttgagaca gaatctttat
    11161 tgtataataa ttataatcaa tacaaaataa taacaaatta tacaaaactt acttatacta
    11221 tttatgctaa aaacaaaaaa tattttatta aagtttttaa aacttatgta atataaaaat
    11281 ctatactata gacttgatta tggaaagaaa attatcaaaa tcattacaat tagatatact
    11341 atctctaata tcattgtcat gaattatctt taaaaggata tcataaatgg agtttatttt
    11401 tatataatca tctttattta tagccaacat catgattaat ttaacagtag aatcttcact
    11461 ccaatatatt ggttcatcca atatggaaat acaaatctta gttcttatag agcttaattc
    11521 cataggatga ggtatagcta aaaaatcatc tatattggta gaagataaac tttctctgta
    11581 aaatacagat tcagcaaatg atggaaatac aatttcactt tgagttaatt tgttgcacat
    11641 caactttata agctcatctt tatctttgat tttaggatta acaataaata aatttttatc
    11701 aaagaaattg tccaaaagat tactataaat atgggaatta ttagtgattg acttagatat
    11761 attctctata tcttttttta atagttttaa atccactaat acaataggaa tactatcatg
    11821 atttaaagga attgtcgata ttattatatc tacatctgac aattcactag ctaaaaattg
    11881 attaaatgat agacattgaa gtatatttat tttatcatga aaaactttgt ttaattgaac
    11941 ctctaataac ctacttgaac cataccctga accacatact aatactacgt ttttacactt
    12001 aatattactt tgaaaaaatc tctctattcc agcacctata tgcagggata catatccaat
    12061 ttcatcttct gttaaagagt aaatactatt tttaaaaact ttttctatag catttaaagt
    12121 tatttcaaat gctaaaggat aattactctt tattgtattt ataaggggat tcaccttatt
    12181 taaattataa gatttagaat tgagaattga tttaaagtgc agtactaaat catcaaataa
    12241 tacactatca tttctaaggt caaaagtata ttgattgttg attacttcta aaatttcttc
    12301 aacatactct ataattttag tatctaccct attggaaacg ttatccaaaa gagaactttt
    12361 agttataaaa tgattatata gataaactct gtctgccttt gaaataatta tagtatattt
    12421 actctcaata taattaaata tattttcaac agttgtattc gattgaaaat ctgttaaaac
    12481 aacatctaaa acattatcta agcagtaacc atcaagtatt ctacttacag taatagctaa
    12541 atggataata aagtttttta gattaaaatc taggaaattg atattaaatt tattaatttc
    12601 acttaacact accctttgaa gctctattaa atctacatta ttaaataatt ctatttctct
    12661 atctgtaatt ccaattatat agttttcaaa attcctattt atcatattat tagaaataca
    12721 tcttcgaata tctatttcct taccttcaac tttaactcca taatatggct tagaaactaa
    12781 tattaaatta tactttgaca aaataggctt tattcttttt atgtcattta gtattgtaaa
    12841 tttactcaca tacaagctat tagctaaatc ttctagtttt atatatgtat tgttatagag
    12901 aatatatttt aaaatatatt gatttctttc tataggagaa tctggtattt cacttgaatc
    12961 cataatatca tcagatatta atgctagata ctgttggtat aatgctaaat taagaatatc
    13021 tatataatat ccttctcctt tttttatttt aataatagca ccatttttct ctaaagttcc
    13081 atttatagaa gtaatatcat ttcttatagt tctctcactc acttttaaat gattacttaa
    13141 agttttacaa gtaattttat catcactttc atttaataat ttaaacaacg tgagcaatct
    13201 cttgtgcata aatatccccc cttatagaat ttcttctaaa ttatactatt tacactcata
    13261 taatacaatt actctaataa aattgtatta taataattta tttccacttc tatatggaaa
    13321 ttagttatta tcataatata aatttccatg tcgaagtgga aattagttat atttaattta
    13381 attaggataa tgattacaat ataaatataa gttaagacat tatgaatgga gtggaaaaat
    13441 atatggtact acaagaaaaa tatatattta tagataaaga cttaaaaagc aaagaagaag
    13501 tattaaattt tattgcagat agtgcttata tactaggtat tacaactaat aaagaggctc
    13561 ttttaaaaga ccttctaaaa agagaaaatg aatttccaac aggaataaaa gatggatttg
    13621 cgatacctca tacaaaaagt gtaaatgtaa aggaagcttc catactctat attaaaacaa
    13681 ctaacgagtt agagtggaaa actttagatg atagtaaggt tagatatgta tttagtttgt
    13741 tagccccaca taaaaatgaa ggaaatatac atttgaaaac tctatctaaa ttagccacat
    13801 gtttaatgga ggatgatttt acaaatgaag ttaaaaatgc tagtgatgca agtcatttag
    13861 taaaatatat aactaataaa atgaaggagg aataattatg aaaatagtag caataacatc
    13921 atgtatagca ggattagcac acacacctat ggcagcaaaa gctttagaac aagctgcatc
    13981 aaaaatgggt catgaaatca aagtagaaca acaaggtgct atgggacgag taaatactat
    14041 aacaaaagaa gaagcacaag atgcggactt tatacttata gcatctgacc aaactatatc
    14101 tggaatggaa agatttgatg gtaaaaaggt gataaaagtc aaaataggta tagcgttaaa
    14161 aaaaccagaa gctgtcttaa caaagtgtat agaagctatt tcttaataaa aaaatctcac
    14221 tctaatatag aatgagaaaa atcaaaaatt aaaaaattgt ctaatgtaat tataacatat
    14281 tatcaaaaaa tataacaaac ttatatagga ggattaaaaa tgagtaaaaa aaataaatct
    14341 cttttaagtg aacttaaggg acacttaatg acaggtatct catatatgtt gccacttgta
    14401 ataggctcat ctttagttgt agctatccca aagcttacag ctttagcaat gggtataaca
    14461 agtttagatg cttataaaaa tgtatctggt ttttatcata ttctttactt aatggaacaa
    14521 gttggttgga ctggcatagg tctattaaat acggtattag caggatttat agcattttca
    14581 ataggtgaga aaccagctat gggtgcaggt tttattggtg ggctcatagc aagtaatact
    14641 aatgcaggat tcttaggagc agtaatagca ggtttctttg ctgggtatgt ttgtaagttt
    14701 ttaaagaaaa aaattaaaat atctgggtca gcatcaggaa tgatgccact tataataatg
    14761 ccacttataa cagttggatt aactggtttt ttaatgagtg ttgtattagc aggaccttta
    14821 ggaaacataa atacttcatt aaatgcttgg gtagctgaaa tgtgtcaaaa tggaacaaat
    14881 tcggtggtat tggctttaat tttaggcgca atgataggat tcgatttagg tggaccagta
    14941 aataaagcag cttggatggc aggaaatgca ttattgttag agggaatcta tctaccagcg
    15001 atattggtaa actgcgcaat agttatacct ccactaggat atggtttagc tacattcata
    15061 agaaaatcaa agttttccaa tgcattagct gaaacaggaa aaggcaatat agttatgggt
    15121 ataattggaa taacagaagg tgcaattcct ttcactttaa caaatccatt aaaattagtt
    15181 cctgttaata tgataggatg cgctttgggt gtaggattat cagctttgtt aggtgtacat
    15241 gctataatgc ctccagttgg tggattatat ggatttatat caataggttc tggatgggct
    15301 tacttagtag gtgcaatatt tggagcttta gtaatagcaa tattatcaac aactttagta
    15361 gacttcaatg aagatgaaac tacggaaaat acagaatttg atgaaataga gttagatata
    15421 atgtaaatta aaaacttaat tttagataat tgagaattga gtgtactctc aattctcaat
    15481 taaattttgg gaggattttt atgaaaaaga caaaagtaca tgtagttcca cacagtcatt
    15541 gggatagaga atggtatttt acaacatcaa ggtcaaaaat atatttaatg aaagattttc
    15601 aagatatatt agacatattg gaagaaaaag aagactttaa atactttact atggatgcac
    15661 aagcttctct cttagatgat tatttaaaat ggagacctca ggatgaatat agaataagag
    15721 atttagttca aagaagaaga ttagttattg gaccttggta tactcaaaca gaccaattgg
    15781 ttatatcagg agaatctata attagaaacc tttactatgg aatagataga tgcaatgaat
    15841 ttggtgaacc tatgagggtt ggatatgtac cagattcttt tgggcaatca gctcaaatgc
    15901 cacaaatata cagaggtttt ggaatagata gttcattatt ttggcgtgga gtttctgatg
    15961 atatggtaga tacaacagag tttatatgga aaggttctga tggttcaaaa gtattagcag
    16021 ttcaaatacc atttggttat tactatggag gtaatatacc agaagatgat tctgatttaa
    16081 aagaatattt aaaagatata atcggaaaac ttaaggttaa agcttctact aataacgtat
    16141 attttccaaa tggatttgac caagcaccaa taagaaaaaa ccttcctgat atattaaaaa
    16201 aagctaatga aatagataat gaaaatgaat acgaaataag tgatatagaa aactatatag
    16261 attcagtaag aaatgaaaga aatgaattta cagagcttaa aggtgaattt ttaaatgcta
    16321 aacatatgag aatacacaaa tccatattct cctcaaggtc agaccttaaa ataatgaata
    16381 acaaattaga aaattatatt acaaatgtac ttgaaccatt attaacatta agttattcac
    16441 ttggaaatga ataccctcac ctagttataa aagatatatg gaaacttatg tttgaaaatg
    16501 cagctcatga cagcataggt tcttgtaata gtgacacaac aaatgaggat gtatacacaa
    16561 gatacaaaca agccagagat ttgagtataa atttattaga tttgcatatg agacttataa
    16621 gtactcaaat caaaaataat aatgaagaaa taacattaac agtattcaat ggattcccag
    16681 aagtcagaaa tgaagttgta gaatttgata cttatattcc aggtcaagat tttgtgataa
    16741 agaataaaaa tggaaaaatt cttaattata taataaaaga aaaagaagat attacaaatt
    16801 atatattaac tcaaacaata agattaaacc caagtaaaaa aatatatata cccaaaactg
    16861 tatatagagc aaaaattgca ctttcagtaa aagatatacc accaatggga tatactcaac
    16921 tagtttttga attggatact aaaaataaat gtgaaataga aacaagtaat tgcaaggaaa
    16981 tagaaaacaa atactacaaa ataacagcca ataaaaatgg ttcattagaa atattagata
    17041 aagaatctaa taagacttat aaaaaccaag ctgtaattga agacaatgga gatgatggag
    17101 attcatacaa ctattctcct ccaagaaaag atatttatgt ttcatcttta gattctgtat
    17161 cttcagtaga agtgctaaaa tcaaacattc aagaagaaat gatacttaaa tattcattga
    17221 ccataccaac ttcactggaa gaaagggcta taggtaaagt ttctgtgaaa atgccagtaa
    17281 caatgaaaat caccttagaa cctaaagaac aaataattaa gtttaatgtt aatataaaaa
    17341 ataaccaagc actatctcat agagtaagag ttttatttaa tacagaaata gcatctaagt
    17401 tttctatagc agatcaacaa tttggaataa tacaaagacc aacagtatta gaaaaagacc
    17461 ttgcattgtg gaaaagagac aattactcat ggcaagaaaa acctataact atcgaaccaa
    17521 tgcaaagttt tgttacttta gaggatggac aaagaggaat agcattaata actggttgtg
    17581 taagagaata tcaaatagtt ggtgataatt tagatacaat agcattaaca ctattcaggt
    17641 catttggata tatgggaaga gaaaatttac tttatagacc aggaagagct tctggagaaa
    17701 aaataatagc aacaccagat gcacaattac ttaaagagtt aaactttgac tttggtcttt
    17761 acatatataa caataaattt gatgaagcaa atgtagctaa tacagctaag agattcttaa
    17821 cacctataca aatatatgaa tatgctgatt ttttaaatgg tagacttata tttgcattca
    17881 atgacgaaaa acaaatatat gaaaatgaat ttagtttgat gaatgtaaat aattcaaatt
    17941 tcacagtaag tgcaataaag aaagaagaaa aaggagatgg aattgtagtt agaatcttca
    18001 atggtatgaa aaatgaggat gctaagggaa gtcttaacat caataaaaat gtcaatgatg
    18061 cttatagtgc aatgctcgac gaaatctatg ataatactag caagcttaaa gtaaatacta
    18121 aaactgtaga ggtaaattct ttatcacatt gtaaagtaca aacaatagta attaaataat
    18181 ataaaatagc ttatacaaga tttcaaaata aattgctagt actatgttaa tagtaaagcc
    18241 agatattatg ctatttataa gctctgtaac actaaataac attttgtaaa ataaaaaggt
    18301 gaaccttgta tattaggatt cacctttttt aaataaatca acattctgtt ttaaaataac
    18361 atttataagc tgttttgaaa taatgcttac aaattatttt aaaacaatac ctataaattt
    18421 ttatttaaag aatacacata aatatttcca gattctttta ttctatagac tttataatta
    18481 ttaaagaagt ctaatctaat ttttgttaaa agtaattgta actttgaata aatcaccatc
    18541 cacacttata ttcatcttac caccctgtaa ttctataaaa ctttttgcta tcgctaaacc
    18601 aagaccagaa ccttctgtgt tacgtgattt atctcctctt acaaatctct ccattatatc
    18661 atctacacta aaatcaatct cagatgcaga catattttta agcataatat ttactttatt
    18721 atctgtttct aaaatatcaa tatacactct tgaatttggc attgcatatt tgcttatatt
    18781 tattataaga ttttcaaata ctctaaatgt acgctgacta tctaatggta atattatttt
    18841 ttcattagaa aagttattct ttactattag agatgaatct gcaagtttgt catctaattc
    18901 taaaagtgtc tgcttcatta gagatacaat atccacattt actatattca aataaacatc
    18961 tccactattt gccttgctta cttcaaacaa atcttctatt agatgttgca atctttgtga
    19021 ctttctgtct aatgtatcaa tatacaactt acgattttca tctgttatac tttcatcttt
    19081 taataaatct atataagtga ttatagatgt tagaggtgtt tttaagtcat gtgatacatt
    19141 tgatataagc tctgttttca tcttttgact cttaacctct tcgtcaacag cttttttaaa
    19201 tccagtttga atatttccta attcatcttt tataggatta aaaaatccta aatctttttc
    19261 catatttaca tctaagtttc catctgaaat tttctttgta acatctaaaa gttgattata
    19321 ttcatatatt gtctttttag agtaatctga cagtatctta aataatacta ctgaatatat
    19381 taatgcgagt attattccaa agaaccacat actacacatt ataactataa tcaataaatt
    19441 tattcccaaa attgtaacta tagttttatt tggcttttct ttcagattta ttgttctaat
    19501 ttgattaata actgcttttc ctgctttttt taaccataca aaaaacattc ctgtcacagt
    19561 atgttttgta aaatactctc ttattccaac atttaaaatg tgttttaaaa gtattataaa
    19621 tacaaatatt attgagaata ttacaaacca ataagttaaa ttcattaaac ttaccaatat
    19681 actagccatt ttagcactta tgtcattgtt tataaggtac tctacataat tcccactcaa
    19741 ggtattactt attataacag taggatataa atctacaagc ccctgtataa tagcaagagc
    19801 aataaagagt atctctaacg gtattcttga taatgtatca aatcctagca actctttaga
    19861 ttttctatat gggaatgcta aagctacaat aacaactata gctaatataa tttttaaaat
    19921 cattccagaa atcttataat aagaattatt ttctacattg cttatatatg aaattatacc
    19981 atcatcaaaa taagtatttc cataaccata ctctacacta tcacctttac ttattacttt
    20041 aggtacagca tatactaatg ttatattttt tattggagat aacttatatg aaattgaatt
    20101 tcctcctaaa cttgtatcca ttaaatcttc tcttgcttta gataacaaca tttgattaat
    20161 aattttttga tttactccat aagaatccac aatatttact tttccatctt tatcaaaatt
    20221 cattacaacg tagaatctat agttttcttt tatatctgta atctgctttt gtctttcctc
    20281 atcattcatt tctgtatttt ttgactgatt ttcattagaa ttttcttttg aagcatcatt
    20341 ttttgttgta tcaagtactc ctaattcttt attatcatta aaaaattcaa aattgctttc
    20401 tttatcaact aaatagtact ttaaattctt tcctgacgct ttaatgaaat gctcccaatt
    20461 ttcaaagttt tcattaaaat ctgcattaat actatcatct gtataataag tttctgaacc
    20521 atcataagta tctttttctt tacttacatt ttttatatag ttcatagttt cttcattgat
    20581 aaatagcttt gatggttgta tcatcttacc ttcttgttct tccttcatat tatgatataa
    20641 aacataactt cctttatata tactatctac aaagctttcc tgttcaaatg gattctctgc
    20701 tccaccttta gcacttgctt gtatagtaga atattgacta atcataccta atgatgctga
    20761 taacataagt ataaaaacta taatagtaac tatatattta tctttaaatt ttttcaattt
    20821 tgtatccaac accccacacc acctttaaat atttaggatt ttttgggtca atttctatct
    20881 tttcccttat attcctcaca tgtaccataa ctgtatctgt atttacagca ttctcattcc
    20941 aaactctttc atatatttca tcagcagaaa aaactcttcc tgcatttctc ataagtaaac
    21001 ttagtatttt aaattctata ggagttgttt ttatatactt tccatcaata ctaacttctt
    21061 ttgtattttc atttaattct aatccgccta ttgcaaacac actatcgtca ctttctacct
    21121 tttgctcttt atttccaacc atgtttagat acttagtgta ccttctaagt tgtgaattaa
    21181 ctctagccaa tagttctaat ggcttaaaag gttttgttac ataatcgtct gctcctatat
    21241 taagccccat tattttgtca acttcttctg attttgcaga tagcattatt actggaaaat
    21301 tatagttttc tctaagcttc attgtaagtg ttataccatc cattttaggc atcattatat
    21361 caactatagc taaatgtatt tcttggtttt ctataacctt aagaccttct aatccattgt
    21421 atcccttaaa aacattatat ccttgattta atagatatat ttctatagca tctgctatct
    21481 ccttttcatc ttctaccacc aaaatattat atgaattcat tctaatctcc tttatattaa
    21541 tttataaatt ttctttacat atatgattat acaatatgat agaagttttt ccatttatat
    21601 atatatttat atcttttgtt ctggttattt gtatttaatg tccatcttag aaacctcctt
    21661 ctagtttaaa tttaatattt tttcattttg ttttatatac t
//
LOCUS       DAGQVA010000070        21336 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.070, whole genome shotgun sequence.
ACCESSION   DAGQVA010000070 DAGQVA010000000
VERSION     DAGQVA010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.070"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     regulatory      118..228
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            332..703
                     /locus_tag="MIV85_002876"
     CDS             332..703
                     /locus_tag="MIV85_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBY2962204.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            800..1747
                     /gene="trxB"
                     /locus_tag="MIV85_002877"
     CDS             800..1747
                     /gene="trxB"
                     /locus_tag="MIV85_002877"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBY2962205.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            1851..2168
                     /locus_tag="MIV85_002878"
     CDS             1851..2168
                     /locus_tag="MIV85_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBY2962206.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            2437..3723
                     /locus_tag="MIV85_002879"
     CDS             2437..3723
                     /locus_tag="MIV85_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBY2962207.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            3835..4308
                     /locus_tag="MIV85_002880"
     CDS             3835..4308
                     /locus_tag="MIV85_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:3967..3969,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBY2962208.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            4340..5650
                     /gene="grdB"
                     /locus_tag="MIV85_002881"
     CDS             4340..5650
                     /gene="grdB"
                     /locus_tag="MIV85_002881"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5387..5389,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBY2962209.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            5906..7438
                     /locus_tag="MIV85_002882"
     CDS             5906..7438
                     /locus_tag="MIV85_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBY2962210.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            7449..8594
                     /locus_tag="MIV85_002883"
     CDS             7449..8594
                     /locus_tag="MIV85_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBY2962211.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            8904..9983
                     /locus_tag="MIV85_002884"
     CDS             8904..9983
                     /locus_tag="MIV85_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBY2962212.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATRLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            10096..10695
                     /locus_tag="MIV85_002885"
     CDS             10096..10695
                     /locus_tag="MIV85_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962213.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(10882..11754)
                     /locus_tag="MIV85_002886"
     CDS             complement(10882..11754)
                     /locus_tag="MIV85_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2962214.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            12171..13574
                     /locus_tag="MIV85_002887"
     CDS             12171..13574
                     /locus_tag="MIV85_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962215.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            13601..15145
                     /locus_tag="MIV85_002888"
     CDS             13601..15145
                     /locus_tag="MIV85_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBY2962216.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKSGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            15176..16567
                     /locus_tag="MIV85_002889"
     CDS             15176..16567
                     /locus_tag="MIV85_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBY2962217.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            16760..18256
                     /gene="abfD"
                     /locus_tag="MIV85_002890"
     CDS             16760..18256
                     /gene="abfD"
                     /locus_tag="MIV85_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBY2962218.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            18391..18666
                     /locus_tag="MIV85_002891"
     CDS             18391..18666
                     /locus_tag="MIV85_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962219.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            18690..19997
                     /locus_tag="MIV85_002892"
     CDS             18690..19997
                     /locus_tag="MIV85_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBY2962220.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            20017..21135
                     /locus_tag="MIV85_002893"
     CDS             20017..21135
                     /locus_tag="MIV85_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBY2962221.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
BASE COUNT         8246 a         2395 c         4204 g         6491 t
ORIGIN      
        1 tgcaaatttt atagaatgtt tatatactta agtcaacaga gatagaaaaa agctatttat
       61 agaaaacaaa ggataaattg cttaatttta aattttctga aaaaaataat aatccggatg
      121 aagagtatgg gagactgctt tataaaaagc gaccgaaggg acaagtttaa tcttacttac
      181 ccaaaagatt agatgaaatt ctcaggtaaa ggtgactgta cttggacggg gctctgaaaa
      241 tgattttaac agggaagaca aattgggaga tttgtttttc ctgtttttta tttatcaagt
      301 aataaataaa agtttgaaag agagtaaaaa aatgataata attacgaata atccaaaagt
      361 aaaagaagaa gttcaaggca gagaagtttt gtttaaagac acaacttata ttggaatctt
      421 agaagcaagt agagatttga tacatgaagg ttatgaactt ttatctcatc cactctatgg
      481 gagtgtaaag ccaaatgaaa caccttacag gactgttata ctaaagaaag gaaatcgttt
      541 ggatataaac tctttaacct taattgaaga agcaatcatc actgcaagta aatttcagaa
      601 taataaaaag actccaaaat ggacagaaag tgttcaagat gattttagag taattgatta
      661 tgatatattt tataatacaa tacaaagaat gcagtatgaa taaaaaaaaa ttgttaaaaa
      721 gttattaaaa cagcctaaat attaaatcta atttaatatt aaataaaatg agaaatttaa
      781 ttggggagga taagtcaaaa tggaaaatgt gtatgactta gtaataattg gttcaggacc
      841 agcagggctt gcagcaggtc tttatggagc aagagcaaag ttaaaaactc taatcctaga
      901 aaaagacaag actggtggac aaattgtaat aacacatgaa attgcaaatt atccagggtc
      961 agttccaaat gcaacaggac caagtttaat agctagaatg gttgaacagt gtaaagagtt
     1021 tggagcagaa atgctaagag acaacattgt tgatactgag ctagatggag atataaaagt
     1081 tttaaaaggg gaaaaggcag aatatagagc aaaagcagta ataataggaa caggagcaac
     1141 accaagaaag attggttgtc ctggagaaaa agaacttact ggtaaagggg tttcatattg
     1201 tgcaacttgt gatgcagatt tctttgaaga ttttgaagta tttgttgtag gtggaggaga
     1261 cagtgcatta gaagaagcaa tgtatttaac taaatttgct agaaaagtaa caattgtaca
     1321 tagaagacaa ggatttagat gtgctaagag tgttgaagaa aaagcaaaag ctaatccaaa
     1381 gatagagttt ttattagata cagtaattga agaaatcaaa ggtgatggaa tattagaatc
     1441 agttgtattt aaaaataaag ttactggaga aactcatgaa tactttgcag atgaagaaga
     1501 tggaacaatg ggagtatttg tgttcgttgg attagatgct caaactgatt tattcaaagg
     1561 taaagttgat atggatgaaa aaggttacat aataactgat gaagatatga gaactaacat
     1621 accaggcgta tttgcagcag gagattgtag atctaagact ctaagacagg ttgtaactgc
     1681 aactaatgat ggagcaattg catctatagt agctgagaaa tacattgatg aaaaatttgg
     1741 gaactagaat ctgtaaatta agaaatagtg tctgtaaatt taatgaataa tatttaaaat
     1801 taaaattaat atttaaaatt aaaataaaaa tttcaagggg gaataagaaa atgttagatt
     1861 tagataaggc tacatttgaa gaagaagttt taaatgcaga aggttttgta tttgttgatt
     1921 tttggagtga aggttgtgag ccttgtaaag ctttaatgcc agatgttcat aaattagctg
     1981 agacttatgg ggataaaata aaattctgta agatggatac aacaaaagct agaagattag
     2041 ctataaaaca aaaagtatta ggtcttccaa ctatggctat atacaaagat ggagaaaaag
     2101 tagacgaagt tactaaggat gatgctacag ttcctaatat agaaaacatg attaaaaaat
     2161 atctttaata tgttgataaa ttattaacat taaaagaaaa aatctatttt tatctgaaga
     2221 taagaagaaa aaggttttta tgtccaactt tgttaaaaaa ataattttaa ataaaataat
     2281 ttttttacaa taaatatttt ttagtaataa aataaagatt taaggcataa aaacacaata
     2341 atatatcttt aaaaaaataa gataaattgt aaaatgatat aattttgaga aaaactcaaa
     2401 tgcatataca caaattaaat aacaggaggt gcaagtatgc gtcttgaatt agggaaaatc
     2461 tttataaaag atattcaatt tggtgatgta acagaagtaa aagatggagt attattcatc
     2521 aataagcaag agatgctaca agaaattggt ggagatgagc atattaaatc tatagatata
     2581 gaattagctc gtccaggtga aagcgtaaga ataacacctg taaaagatgt tattgagcca
     2641 agagtaaaag ttgaaggtaa tgggggaatc ttccctggta tcatgtctaa agttgacact
     2701 gtaggagaag gaaaaactca tgctttaaaa ggtgtagctg ttgtaactac tggaaaaata
     2761 gtaggtttcc aagaaggtat aatagacatg actggagaag gagctaagta cactccattt
     2821 tctaaattaa ataatgtagt agtaatagct gaacctattg atggtttaaa acaatacgct
     2881 catgaaaaag ctgttagaat gataggattc aaagcagcaa tgtacttagg agaagtagca
     2941 agaaatctta ctccagatga agtttcagta tatgaaacta aacctcttct tgaatcaata
     3001 aaagaatatc cagagcttcc aaaagtagga tatgtttaca tgcttcagac tcaaggttta
     3061 ttacatgata cttatgtata tggagtagat gcaaaacaaa tagtaccaac tttattatat
     3121 ccaacagaat taatggacgg agcaattgta agtggtaact gtgtttctgc atgtgacaaa
     3181 aacccaagtt atgttcatat aaacaatggg gttgttgaag acttatatgc aagacatggt
     3241 aaagatataa actttgtagg tgtaattata actaatgaaa atgtttatct agcagataaa
     3301 gaaagatctt caaactggac ttctaaatta tgtaaatatt taggattaga tgcagttata
     3361 gtttcacaag aaggttttgg aaatcctgat actgacctta taatgaactg taagaagata
     3421 gaaatgcaag gtgttaaaac agttatagtt acagatgaat atgctggacg tgatggaggt
     3481 tctcaatcac ttgcagatgc agatgtaaga gctgatgctg ttgtaacagg tggaaatgcc
     3541 aaccaagttg tagttcttcc taagttagat aaagttattg gacatttaga agtagtagat
     3601 gtaatagctg gtggttctga tggaagttta agagctgatg gaactattga agttgaaatc
     3661 caagctataa caggtgcaac taatgaaaca ggatttggtc atttaactgc taaaggatat
     3721 taagaagtat tttattaaac gattgagtaa tgttaataaa acatattata gataattata
     3781 ataagtgtta tagatatata aaaatatatt agaaatataa taaggaggat tattatgagt
     3841 ttacttagta ataaaaaggt tcttataata ggtgaccgtg atggtatacc aggacctgcg
     3901 atagaagaat gtgtaaaaac agtagaagga gcagaggttg ttttctcatc tacagaatgc
     3961 tttgtctgaa cagctgctgg ggctatggac ttagaaaatc aaaacagagt taaagatgct
     4021 gctgataaat tcggagctga aaatgttgtg attttactag gtgctgctga agccgaagct
     4081 gcaggtcttg cagccgaaac agtaactgct ggagatccaa ctttcgctgg accacttgct
     4141 ggagttgcct taggattaag tgtttaccac gttgttgagg aaccaataaa atcattattt
     4201 gatgaaagtg tatatgaaga ccaaataagt atgatggaaa tggttttaga agttgaagaa
     4261 atagaagaag aaatgtctgg tataagagaa gaattttgta aattttaatg cctaaaagca
     4321 aaaggggtga aactaagaga tgggaaaact aaaagcagta cattatatta atcagttctt
     4381 tgctggtata ggtggagaag aaaaagctga tactaagcca catgtggcag aaactttacc
     4441 tccaataagt ttacaacttg ataaattatt aggtgaagat attgaaatag ttggaacagt
     4501 agtttgtgga gatagctatt tcaatgaaaa tatagatagt gcaagtgaag aagttttatc
     4561 aatggtaaaa ggttttgaac cacaactttt catagctggt cctgcattta atgctggtag
     4621 atatggggtt gctgctggaa caataactaa agttgtaaaa gatgctttga atataccagc
     4681 tttaacaggt atgtatgttg aaaatccagg agcagatatg ttcaaaaagg atgtttatgt
     4741 agtagaaact tctgattctg cagcaggtat gagaaaggca cttcctaaga tagctaaact
     4801 tgcagtaaaa cttgctaatg gagaagaaat tggaactcct aaagatgaag gatacatagc
     4861 tagaggaata agagttaact acttccatga agacagaggt tctaagagag ctgttgacat
     4921 gttagttaag aaaataaaag gtgaaccatt tgaaactgaa tacccaatgc caaactttga
     4981 tagagttgac ccaagtaaag ctgtaaaaga tttatcaaaa tgtaaaatag ctttagttac
     5041 ttctggtggt atagttccaa aaggaaatcc agatagaata gagtcttctt cagcttctaa
     5101 atatggaact tattctatag caggagttat ggatttaaca gaagagactt atgaaactgc
     5161 acatggtgga tatgacccag tgtatgcaaa tttagatgca gatagagtat tacctgttga
     5221 tgttcttaga gatttagaaa aagaaggtgt aattggaaaa ttacatgaga ctttctatac
     5281 aactgtaggt aatggtacat ctgttgcaaa ctctaaaaaa tatgcttctg aaattggagc
     5341 agcattagtg gctgatggtg tagatgcagt aatattaact tctacatgag gtacttgtac
     5401 tcgttgcggt gcaacgatgg taaaagaaat agaaaaaact ggacttccag tagttcatat
     5461 gtgtacagta gtacctattt cattaacagt aggggctaat agaatagttc caactatagc
     5521 aatacctcat ccacttggaa atccagcgct tgaccctaca gaagaaaaag ccctaagaag
     5581 aggccttgta gaaaaagcat taaatgcttt aactacagaa gtagatggtc aaacagtatt
     5641 tgaaaaataa aaataacaca cacatatatt atatagataa aaatataaac acacactaaa
     5701 aataaaaaat aactatacac aaaaaaataa tatagatttc atgaatggat aaattggagt
     5761 tattcattca tgaaatctta aaaaatgcca aaatacataa acaataatag aatcaaatat
     5821 acaataaaat acaatgatta gagcttttaa taagtttaat aagattaaaa aataagtgtt
     5881 cataaaattt atggaggtgc acaaaatgac ttatccagtt ttaaaagggg caggctatgt
     5941 acttattcat actccagata tgatagtgca aaatggaagt acttgtacag ttgaaagagc
     6001 aacaaatcca gattcagaat ttttaaaaga agtaagtaat catataagaa gttatgaaga
     6061 tgtagttaac tacatgccaa atcaagttta tataggaaat agaagaccag aagaattaag
     6121 agatttacca atgccatggt gtgaacaaaa gattgaggga actagaaatg gtaagtttgg
     6181 agaaataatg cctcaagatg agttcatagc tttaatgcaa ataagtgatg catttgattt
     6241 agtaaaatta tcacaagaat ttattgatga agtaaagcca aaaatcgaaa ataactaccc
     6301 tgaaattgca ccatttgtag gtaaattaaa gggtgatgat atagaagaag gtaaagaatt
     6361 agtagcaaca cacatagctg aaggattata ccatgatgga aaatttgttg gttatgtaaa
     6421 aagagcacat gatgtagatg ttaacttaaa tgcccataca atgtttgaaa atctagtagt
     6481 aaaagcatct ggagttttat ctgctattca aatgctaaga catagcaaaa tagaccctgc
     6541 tgaaatagat tatgttattg agtgttcaga agaagcttgt ggagatataa accaaagagg
     6601 tggaggaaac tttgctaaat caatagctga gatagcagga cttcaaaatg caactggttc
     6661 tgacacaaga ggattttgtg cagcaccaac tcatgcatta attcaagcag cagctttagt
     6721 aaaagctggc atacataaaa atgtaatggt agtagcaggt ggagcaagtg ctaaacttgg
     6781 aatgaatgct aaagaccatg ttaaaaaagg tcttcctgta cttgaagatg ttgttggagg
     6841 atttgcagta cttgtatctg aaaatgatgg tgtaaatcca gttataagaa ctgatttaac
     6901 aggtaagcat actgttggaa ctggttcttc accacaagca gttatgacag cacttataac
     6961 ttcaggtctt gatagagcta atttaaaaat aacagatgtt gatgtgtatt cagttgaaat
     7021 gcaaaaccca gatataacta agccagcagg agcaggagat gttccagaag caaactacaa
     7081 aatgataggg gcacttgctg ttaaacgtgg agacttagaa aagaaagaat tgaaagattt
     7141 tgtttctaac aaaggattac caggatgggc accaactcaa ggacatatac catcaggagc
     7201 tccttatata ggatttttaa tagatgattt aactacagga aatagaaata gagctatgat
     7261 agttggaaaa ggtagtttat tcttaggaag aatgactaac ttatttgatg gagtatcttt
     7321 tatagctgaa agaaatacag gtgttactga agagacttca ggaatatcta aggatgaaat
     7381 taagaagata atagctgaat ctatgaaaaa actagcatta gatatgttag aagaataggg
     7441 gtgaggatat gtcaaaaaaa gtaatcgcag atgtattctt agaagtagct aatgcaatag
     7501 aaagcggcga atttggcaaa aaagtaaaaa ttggtgttac tacacttgga agtgaacatg
     7561 gtgtagaaaa catggttaat ggtgcacaat tagcaaaatc taatttattt gatattgtgc
     7621 ttattggacc aaaagtggaa actgaccttg aagtagttga agttaatgat gaaaaagaaa
     7681 tgcatgcaaa aatggaagaa ttattagatt caggatatat tgatgcttgt gttactatgc
     7741 attataattt tccaataggt gtatctacag taggtagagt aataactcca gcaaaaggaa
     7801 aagaaatgat acttgcaaca acaacaggaa caagtgctac taatagaata gaggcaatgg
     7861 taagaaatgc catttatggt attgctacag ctaaatcaat gggtaacaaa tgcccaaaag
     7921 ttggaatact taatgttgat ggagcaagac aagttgagaa gtgcttaaaa gaattaaaag
     7981 ataatggata tgacatggag tttgcggatt caattagagc agatggtgga tgtgtaatga
     8041 gaggtaatga tttacttgta ggtgcacctg atgttatggt tactgataca ttatctggaa
     8101 atatatttat gaaagtattt tcttcatata ctacaggtgg agattatgaa gctcaaggct
     8161 ttggatacgg acctggagtt ggagaggact atgatagaaa ggtacttata gtatcaagag
     8221 catcaggttc tccggtagta gcaaatgctt taaaatacgc ttatgatgtt gtaaagggag
     8281 atataagtaa tgttgcaaga aatgaatttg caaaggttaa aaaagcaaaa tttgatgaca
     8341 ttatatcctc tcttactaaa aaagaagtta aagctgaaaa agtagaagtt aaaatgccag
     8401 ataaagaaat tgttactcgt caaatagctg gtgttgatat aatggattta gaagatgcag
     8461 tatctgagtt atggaaaaac ggaatctatg ctgaaagtgg tatgggttgt acaggtccaa
     8521 tagttttagt aaatgaagct aaaggagact tagcagttga aactttagtt aaagctggat
     8581 atactgcaaa ataagtacat tttttatatg taaataagaa catatagtta taattttatt
     8641 gattataatt atatgttctt tttattttat atcttgtcaa tatttatata ttaacacaat
     8701 ccatttattt gattctctag ctaatttatt atatttattc aattaaaatt aagctttcta
     8761 actaaataaa aactaatgaa gtattaaaat gaaattgata aaatatgaaa aaattttagg
     8821 aataaagtat ctgttagata aaaataagat taattagtga tataatataa ttaagataaa
     8881 atttattatt tggaggtaaa atcatgagca gagtaaaaaa tgtagtagaa ttgttggaaa
     8941 ctaaaggtgt tgatgcacta tatctaacaa agaaaactaa tgtaaactat ataagtggtt
     9001 ttcctgatga agaagcatat gcagtgattt gcaaagatgg aaacttttta gttactgata
     9061 gtagatatat ggagcttgca gaaaaggttt gcaaagattt tgaaattata aattggcata
     9121 attttgatag aagtgtggca aaggcagtta aaagtgtatg tgataaagtg ggtataaaga
     9181 aacttggatt tgaaagaact aatatagtgt ttgataaata tgaagaactt aaaaatctga
     9241 ttgagaagga taatggagaa ttaataccta cagaaaatat tgtagagact ttgagatatg
     9301 taaaagacaa agatgaaatc aaaaatacaa gaaaagcttg tgaaatagcg gataaggcat
     9361 tagaagaatt gattccacat ataaaagctg gagttagcga aattgaactg gctacaaggt
     9421 tagagtactt tatgaaaatg aacggagcac aaaatatagg gtttgaaact atactgatat
     9481 caggagcaaa gacttcattg cttcatggta agcctagtga taagattata gaaaaaggtg
     9541 attttgtact tatagactat ggtgctatgt ataatggcta tatatctgat acaactagaa
     9601 cttttatagt tggaggagct tctgaaaagc aattagaaat atataattta gttaaggaag
     9661 ctcaaaatgt aggggttgag aacatgaaag ctggtgtaca tgcgacaatt ccagatgctg
     9721 agataagaaa agttgtcaaa aaatatgaag actattacta tcaaggtata ggacatggag
     9781 tcggtagaga tgttcatgaa gaacctttca ttggtaatta tggtgataaa atcatagaag
     9841 agggatgtat aataacaatg gaaccaggta tttatttccc tggatggggt ggagttagaa
     9901 tagaagatac tgttttgatt actaaaaatg gtccagaaag acttactaaa ttccctaaag
     9961 atttgatgat tttagacaaa taatttaatt tatatatatt tttttacata aaatataaca
    10021 taatctcact attaagctct atttacatat tatagtaaag agggcttaat tttattgtga
    10081 gaggtgatag tatatatgta taaaaaacat aaatttataa aaaatataaa aaaagcctgg
    10141 tataaaatca aattaattga tagatgcctt ataattgtaa tggcaatatt aatgtttcaa
    10201 tctatatata acttatttgt taatgaagta aattcacaag atactacaac tattgatgta
    10261 gtagtaagaa ccacttcagc agctatattt gggtattttt taagtgctaa ttttataaag
    10321 agacctttaa ggaagtatac aaatactgat gtatcttcaa atctttttat agataataat
    10381 ttatccccaa aaggtcaaga gtctaatcaa aataatataa tgaatgtcaa aaataccatt
    10441 ggatttactt cagaagctga taattatgaa aagaaaatac ctattaataa taatgaaggt
    10501 tttgaagaag gagaaactag tgaattgcaa attattatag ctactgtaat ttgcatagta
    10561 gcattaacag tactttttgt tgtaagaaat tttacaacta caacatcagc ttctttaggt
    10621 actatttcac agatgagaga ttttgtctca ggatgcgtgg gttttttgct aggttgtcca
    10681 agtaaacctg attaaaaaag tattatcaat aaaaggtatt ttaaaaagta tcagtataat
    10741 aatatttaga tttaaatgta tacaattata attctgtaac attctatatt gtatttttat
    10801 actgatactc taaactatac tatttattaa aatattttaa cattgtattt aaacaaaata
    10861 ttatatctgt ataatataaa tttagtttat atgaatagat gccatatact caataaaaag
    10921 tttcatacta tgagatatgt attgatttct tctccaaaga accccaatat ttgcagtaat
    10981 tgcacgttct aatggtattg aacagagatt ttctgtattt tgaaatattt ctttatacaa
    11041 tattgttgaa gccaagtcat tttctagtaa ataacgtatg gtagaaagtt gatttgagtg
    11101 taaaattata tttggcttag ctttttcaag tctttttgta ataatcttat agtgataaga
    11161 accttcagat aagattacaa aaggtacatt ttttaacata taattcgata taataggatg
    11221 ttttgccaat tcatttttgg gatttgtaac taagtataat tctgttttat agattgtctt
    11281 tgaatctata tcatcataaa tatcactgtc aattatacca atacaaaaat caagtgtaga
    11341 ttcttcaatc attttagctc caacaaatgt tggaacttca aaaattttaa gctctatatc
    11401 tggataaatt acattaaacc taggaagtat ttttgaaagc aaaaacgtac ctaaaactgt
    11461 aggaatacct attttgagag aagcttttct cttttttcct aaatcaagtg cgtcacattg
    11521 aaaatcctca aattgtttta taaaatgttt tgacttgtct aaaaaaattt ttccttcagg
    11581 cgttaactct attttattac ctattctgta aaaaagttca aagccaagtt ctttttctaa
    11641 ttctttaatt gctaatgtta tggatggttg agaaatatga atactttccg cagccttagt
    11701 catgttttta tatttacaga cagtttgaaa atagtataaa tagtttatat tcatttggta
    11761 ttagttcctt tcatttacat attagtgaca agtatataat taacaatagc ataagttttg
    11821 tatattgttg taaaaaaata gaatagtttt aaactatcat agcataagtt tttgatattt
    11881 tcaatctatt aagaatagtg ctattattaa attaacaaaa gagaatagct ggtatggttt
    11941 agagtaaatc aatctatatt acagttatat caacgaatat caaaaaatta tctattaaaa
    12001 aataaaaatt atttttacaa ttaaattgtt aattaaatca taaagaaaaa agtgatatta
    12061 acaagataaa atttttttaa tcagaaatgt taatttaata acaaaataga gtattgggga
    12121 gaaaggagaa atatattttt taataatatt tgttaattta ataacgaaaa atgaaaggga
    12181 gtgatttagt gaagtttgaa ttgatggatt ttttaatgaa tccttttgtc cttatgtttg
    12241 ctgcagtaat tacaggaatt ttatttggaa aaattaaatt tgggaagttt aattttgggg
    12301 tatcaggagc attatttaca ggattattta ttggatggct tgcatatagc ttggggaatc
    12361 taataatagc aaaaggggaa acagcagcag gatataaggc agcaactgta atgatgggga
    12421 atggaattat ttcttctgac ttctttgatt tctttttaat aatatttgtt gcagcagttg
    12481 gtctattggc agcaaaagat atgaaagctg tattaaagaa gtatggagca agatttgtaa
    12541 ttttaggagt tcttataact tttataggtg gctctatgac ttatgcaatg actttactat
    12601 caagtgataa aggaagtagt gcttatgaag tttctggcgt ttacacagga gcattaacaa
    12661 gttcgcctgg attagctgct gctttagaaa cagctggtaa acatgcagaa gatgtatcaa
    12721 aagaatttga aaaagcttca ataaaagata aaaaagaaat tttaaaagta gtcgacccag
    12781 aaggcaaatt ggatgtgaat acaactacat cactgactca agagcaaata gataagtata
    12841 ttgcatatgc tgaagctggt gttggtatag gtcatgcagt cgcatatcct tttggagttt
    12901 taatagtaat cttaggtgta aatttccttc caaaattatt taggatggac ctaaaagaag
    12961 aaagaagaaa atatgagaag gaaatgaagg aagcaagaga tagtgtttct ggtaaaacga
    13021 taccagaagt tccatttaat ataataacat ttttcttgac atgtttagct ggatacttag
    13081 ttggaggaat acatgtattt atgggaccac tagggtactt cacactaggt gcaacaggag
    13141 gttcactaat tgtatctcta gttcttggat atataggtaa gataggggta gtaaatttca
    13201 gaatggaaga aaaggtttta aatattttaa aacaaatagg gctagtgttt ttcttagcaa
    13261 tagttggatt aagatatggt ggaaaagtag ttgattcaat tatgacatct ggtatgcacc
    13321 tagccttagt agcaatagca gtaggtgtta cagctatgat gataggattc ttagttggca
    13381 aatacgtatt taaattaaat tggattttat tatctggagc tgtctgtggt ggtatgacat
    13441 caacaccagg tcttggagct gctgttgatg ctcttgatag tgatgaccca gcagcaggtt
    13501 atggtgctac gtatccattt gcattattaa ctaaagttat attggttata gttttacaca
    13561 aacttccaat gtaaataaga ttttatatgg ggggatattt atgaataatg aaggagcatt
    13621 tgaagaatta agtggaagat taagaaataa agaattgtgt gatttaataa tgaatgcaga
    13681 tgaagctgct aaaattatag aggatggcat ggttattgga gttagtggat ttacaccttc
    13741 aggctatcca aaagcagtac cattagcagt ttcagaaaga gctaaaagtg gagaaaagat
    13801 aaaattaacc gtatattcag gagcatcttt aggtccagaa gttgatggag catggtcaga
    13861 agcaggtata attgaaagaa gacttcctta tcaaactaat tcaatactta gaaataatat
    13921 taataaaggt gttgttgatt atatagatat gcacctaagt cattctactc aatttttaaa
    13981 ttatggaact atacctaaag tagatgtagc tatagtagaa gcacttgcaa taactgaaga
    14041 agggaatatt ataccaacta gtgggatagg taattctcca tcttttataa aaagtgcaga
    14101 taaagtaata gtagagataa atcttgcaaa accaatggaa atggaaggta tggcagatat
    14161 atatattacg gaaaatccac caaatagaaa accaatagaa ataaatcatc ctaaggatag
    14221 aattggaaca acatatatac cttgtggttt ggataaaatt gcaggagtag taattaccaa
    14281 tatgcaagat aagacccgtc cattgggggt tgtagatgaa gcttcgaaaa aaatatcaaa
    14341 taatattatt gcttttttaa gagaagaagt aaagtcaggc agattatcaa agaatttact
    14401 tcctcttcaa tctggtgtag gaagtgtagc aaatgcagta ttatatggat tatgtgaatc
    14461 tgaatttgaa aatttaactt gttatacaga ggttgtacag gactctatgt tggatttaat
    14521 aagaatgggt aaagttacaa tggcatctac tacatctgta agtccatctc cagaaggatt
    14581 aataaaattt gaaaaagata ttgatttttt taaggataag attatattaa gacctcaaga
    14641 aattagtaac aatccagaaa tagccagaag aattggtgta attgcaatga acactgcaat
    14701 tgaagttgat atttatggaa atgtaaattc tactcacata atggggtcaa agatgatgaa
    14761 tggaattggt ggttctggtg attttgctag aaatggagca ataactatat ttagtactga
    14821 gtcaattgca aaaaatggtg atatatcatc aatagtacct atggtatctc acgtagacca
    14881 cactgaacat gatgtaatgg taattgtaac agaacaagga tatgctgatt taagaggtct
    14941 tgcacctaga gaaagagcta taaaaataat agaaaattgt gcccatccag attataaaga
    15001 acaacttagg gattatttaa atagagcttg taaaagtgga gcaaaacaaa cacctcacat
    15061 attggacgaa gctttatcat ggcatagtaa atttatgagt acaggtacaa tgaaaaaggc
    15121 tgaaactttt aaaagtgcat tataaaatat ttaataaatt ggaggtagat tttaaatgga
    15181 aaaagcagtg gaaaactttg aagatttaag taaggaatac attaatggtt atattgagag
    15241 agcaagaaaa gctcaaagag agtttgaatg ttatactcaa gaacaagtag ataaaatagt
    15301 aaaaatagtt ggaaaagtag tgtattataa tgctgaatat ttagctaaac ttgctgtaga
    15361 agagactgga atgggagtat atgaagataa ggtagctaaa aataaaagca aagcaaaagt
    15421 tatatataac aatttaaaag ataaaaaatc agttggtata attgatatag atagagaaac
    15481 tggaataaca aaggtagcta aaccagttgg agtagtagcg gcaataactc cttgtacaaa
    15541 tccaatcgtt acacctatga gcaatgcaat gtttgcactt aagggaagaa atgcaattat
    15601 tatcacacct catcataaag caattggatg tagtacaaaa actgtagaga tgattaatga
    15661 agaattagaa aaaataggag ctccagaaaa tttaatacaa atacttgacc aacaatcaag
    15721 agaaaataca agaaatttaa tttcatcagc agatgtagta attgccactg gaggaatggg
    15781 aatggtaaaa gctgcgtact caagtggaaa accagcactt ggtgtagggg caggaaatgt
    15841 tcaatgtatc atagatagag atgtagacat taaagaagca gtacctaaaa tcatagcagg
    15901 aagaattttt gataatggta tcatttgttc aggtgaacag tcagtaatag tagcagaaga
    15961 aatgtttgat aaaataatgg atgaatttaa aaataataaa ggttttatag ttagagataa
    16021 agtacaaaaa gaagctttca gaaatgctat gtttgtaaat aaatctatga ataaagatgc
    16081 agtaggtcaa tcagttcata caattgcaaa aattgcaggt gttgagatac cagaagatac
    16141 aaaaataata gtaatagaag ctgatggacc aggagaagag gatattattg caaaagaaaa
    16201 aatgtgtcca gttatatctg catacaagta taaaagtttt gaagaaggtg tagctattgc
    16261 aaaagcaaat ttaaatgtag aaggaaaagg acatagtgta tctatacatt caaatacagt
    16321 taaaaatata gaatatgcag gagaaaatat agaagtatca agatttgtta ttaatcaatg
    16381 ttgtgctact agtgctggag gaagtttctt taatggtctt gcacctacta atactctagg
    16441 ttgtggttct tggggaaata acagcatctc tgaaaatctt gattataagc atctaattaa
    16501 tatttctaga attgcttatt atatgccaga aaatgaagtc cctacagatg aagaactttg
    16561 gggataaaat ttagacaaaa aatattcatt ctaaattaaa gtaggaatat attttaattt
    16621 agaatgaatt taagacataa attaaattta aattagttta ttggactaaa tttaaaatat
    16681 taagagacat atagaagaag gaagtattat aatttaaaat aaataaaaaa atctataaaa
    16741 gagaaggagt ggttttatta tggcattaat gacaggagct caatatattg aaagtttgag
    16801 aaaattaaat actaaggttt atatgtttgg tgaagaggtt aagaattggg ttgaccatcc
    16861 tatgattaga ccatctataa attgtgtagc agcaacttat gacttagctc atgacccaga
    16921 atatgcagat ttaatgacag ttacttcaaa tatcacaggt gaaaaaataa atagatttgg
    16981 tcatcttcat caaagtgttg atgatttgat aaaaaaagta aaaatgcaaa gactatgtgg
    17041 tcaaaaaaca gcttcttgtt tccaaagatg tgttggtatg gatgcgttta atgcagtgta
    17101 ttcaacaaca tttgagtgtg ataaagccca tggaactaat tatcatgata attttgtaaa
    17161 atacttaact tatatacaag aaaacgattt agtagttgat ggagctatga ctgaccctaa
    17221 gggagataga agtctatcac ctagtgctca acctgaccca gatatgttcc ttcatatagt
    17281 agaaagaaga gaagatggga taattgtaag aggagcaaag gcacatcaaa ctggttcaat
    17341 aaattcacat gagcacctta taatgcctac tataagtatg actgaagcag ataaagacta
    17401 cgctgtatca tttgcagttc cttcagatgc tgaaggagtg tttatgattt atggaagaca
    17461 atcttgtgac actagaaaat tagaagaagg tgcagatgtt gatttaggaa ataaggagtt
    17521 tggaggtcaa gaagctttag tagtatttga taatgtattt gttccaaatg atagaatttt
    17581 cttatgtgga gaatgggatt tctctggtat gttagtagag agatttgcag gataccatag
    17641 acaaagttat ggtggatgta aagtaggagt aggtgatgta ataataggag cagcagcttt
    17701 agcagctgat tataatggag caaacaaagc ttcacatata aaagataaac taatagaaat
    17761 gactcacctt aatgaaagct tatattgctg tggtatagca tgttcatcag aaggtcacaa
    17821 aacagaagct ggaaactatc aaatagattt acttcttgca aatgtgtgta aacaaaatgt
    17881 aactagattt ccttatgaaa tagtaagact tgcagaagat atagctggag ggcttatggt
    17941 tactatgcct tcagaaaaag actttaaatc agaccttaaa gttggaacaa gtggaatgac
    18001 tattggcgaa gtatgtaaca agtattttaa agcttcttca gtggcttcaa cagaagaaag
    18061 aatgagaata ttaagattct tagaaaatat atgccttggt tcatctgctg ttggttatag
    18121 aactgagtca atgcatgggg caggttcacc acaagctcaa agaataatga tttcaagaca
    18181 aggaaacata aatcaaaaga aagaattagc taagaaaatt gcgggaataa aaaaagagga
    18241 agctttaaat ttataaaaag ttgatatata aagggaaatt atatattaat gtgtattaat
    18301 taatgaaaaa atatgtagta taagagatag ttataaaatt atggtggttt ttagctaagt
    18361 aaagaaattt ttaataagga gaatttacac atgacctgtg gagttagatt ttgtgggggc
    18421 tgtaacccta gatacgaaag agggaaggct cttacaataa tcaaagagca cttcaatggt
    18481 agggtagatt ttagtatagc acaagagaac gtcgagtatg atttgctact tataattgga
    18541 ggatgcgcaa ctctatgcgc atcctatcaa caatataaag tgaaaaatga atgtgttaag
    18601 atgtgggatt ttagccatat agaaagagtt ataaatgtga ttgaatcagc aatttgtgaa
    18661 acttaaaaaa gctaaatggg gggatttcat tgagttggca agaattgtat caaagtaaat
    18721 tatgtagtgc tacagaagct gtaaaacaga ttaaaaacgg tgatactgta gtatttgcac
    18781 attgtgtagg tgaacctcct gcactagtag aggctatgat tgaaaatgct gaacaatata
    18841 aagatgttga gattaaacat atggtaagct tgggtagtgg tggatatact gctaagggaa
    18901 tggaagctca ttttagagta aatccaatgt ttgtaagtgg aaatgtaaga aaggcaattg
    18961 aaaatggaga tggtgatttt acacctgcat tcttccatga agtaccaaag ttgcttagag
    19021 aaaaaagatt aaaatgtgat gttgttttag cacaggtaac tccaccagat gaacatgggt
    19081 attgtagctt aggaacatca gttgattata cttatgaagc cattaaaact gctagaacag
    19141 taattgttca agtgaatgac cagtttccta gaacctatgg tgaggtagtc catgtatcag
    19201 agtttgacta tatagtggaa aaatcacaac ctttatttga actacaacct gcaaagattg
    19261 gagaagtaga agaagcaatt ggtaaaaatt gtgcttcatt aattgaagat ggttctactt
    19321 tacagctagg gattggtggg ataccagatg cagttatgtt atttttaact gataaaaagg
    19381 atttagggat tcattcagaa atgatttcag atgggacttt ggccctttat gaaaaaggtg
    19441 ttataaatgg taaatataaa aattttgata aagaaaaaat gacagttacc ttcttaatgg
    19501 gtactaaaaa attatatgac tttgcaaata ataaccctgc agtagaggta aaaccagtag
    19561 actatgtgaa tcatccagca attataatga aacaacataa gatggtttct ataaattctg
    19621 ctatacaagt tgatttaatg ggacaggtag ttgcagaggc tatgggactt agacaattta
    19681 gtggtgttgg aggtcaagtt gactttatac gtggagtgtc tatgggtgaa gatggaaagg
    19741 caattatagc tatgccttca ataactacga aaaaagatgg tacagtaatt tcaaaaatcg
    19801 tgtctattgt ggatgaaggt gcacctataa cgacatcaag aaatgatgtt gactatattg
    19861 taacagaata cggtatagca gaattaaaag gaaaatctct tagagaaaga gcgagaaatt
    19921 taataaatat agctcatcca agtgtaagag aaagtctagc agtagaattt gaaaagagat
    19981 ttaaggagaa atattaataa tagaggggtg ttaataatgg aagcacttag agtagttcca
    20041 aagatatttt actttgatac atttaaagaa tttaatgaag aatttaaaat aggaaaaaat
    20101 gatttagtaa ttactaatga gtttatatat gagccatata tgaaacctct tggaatagat
    20161 acaaatttaa tttttcaaga aaagtttgga acaggtgaac catctgatga aatgatagac
    20221 tccatgacaa aggaaatgaa gaaatacaat tttgatagaa ttattgcatt tggaggagga
    20281 acaatagttg atatatgtaa gatattagca cttgatgttc cagaaaagtc tattgattta
    20341 tttgaaggag aagtatcacc taaaaaagta aaagagttag tagtagttcc tacaacatgt
    20401 ggtacaggta gtgaagtaac aaatgtagct attgcagagt taaaatctaa acatactaaa
    20461 aaggggcttg cagtagaaga aacatatgca gactatgcag tgttaattcc agagacagta
    20521 aaagggttac cttacaaatt ctttgttaca agttcggtag atgctcttat acatgctatt
    20581 gagtcttatc tttctccaaa agcaagtcca tttacagaga tgtattctct acaagcaata
    20641 aaaatgatta tggatgggta taagaagata gttgataaag gagaagaaga gagatttaat
    20701 catcttagag actttgtact tgcatcaaat tatgcaggaa ttgcttttgg aaatgctggt
    20761 tgtgcagcag ttcatgcact atcttattca ataggtggag ctttccatgt tgcacatggt
    20821 gaagcaaatt atcagttctt tactgaagta tttaagatgt attctagaaa aaaacctaat
    20881 ggaaaaatta taaaatgtac aaaaatttta gcagatgccc ttgaatgtga ccctaactgt
    20941 gatgtttatg gagaattaga aaagttttta aataaattaa tagctaaaaa agctttgaga
    21001 gaatatggaa tggtggaaag tcagatagat gaatttacag atagtacaat agcaaatcaa
    21061 caacgactac ttgctaataa ttatgtagag cttagtagag aggaaataag agagatattt
    21121 gcaaatcttt attaatacaa ttttttattt atatgtatag tcaacataaa caatgctaat
    21181 tatatttatg tacaaataaa aataagggaa cttaaatttt aattaaagtt aagttctctt
    21241 atttttatat ggagttaaat ataagtatat ttttaattta aaatatgctt atatttaagt
    21301 ctattacttt atttgaaaca atttgtagaa tttcaa
//
LOCUS       DAGQVA010000071        21130 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.071, whole genome shotgun sequence.
ACCESSION   DAGQVA010000071 DAGQVA010000000
VERSION     DAGQVA010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21130
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.071"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..679
                     /locus_tag="MIV85_002894"
     CDS             <1..679
                     /locus_tag="MIV85_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962222.1"
                     /translation="LSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALK
                     NIEASLNNTLVELSEKIKTSFDSSDTSVQDLQNQVTQKNNTITQLETELSKRKRFITG
                     TYTFTKTDAENFNLSIYDKEGTSKTLTIPVNMGFSPSLIVLSGVTFSTTSKSYVYFDN
                     VCNSNFYNFGYNSDSTHSNPKAVGILNVSNVGYSSLVLTLYKLSMSEAVGIWAKEGAT
                     LTYKIYI"
     gene            700..1047
                     /locus_tag="MIV85_002895"
     CDS             700..1047
                     /locus_tag="MIV85_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962223.1"
                     /translation="MNRNNRIIYDQTGNIWLQTGEATGDIQEWSKITELNFLDVEFGS
                     IDYSKQYIESINPVTKEPIIKDIEVILTDEQKRLQALEKELSMLKEENKNRDSEIVNT
                     AFEVENIKLNNNL"
     gene            1059..1229
                     /locus_tag="MIV85_002896"
     CDS             1059..1229
                     /locus_tag="MIV85_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962224.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKIDVFYAVNRITEEQYLELTSL
                     LNKEETPAEPIK"
     gene            1260..1826
                     /locus_tag="MIV85_002897"
     CDS             1260..1826
                     /locus_tag="MIV85_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962225.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTESKFTSENVEGALKECIDR
                     ADEAFQEADSGKTLLSTAIGSPATSEQTFQDYANYITGFKSNISNLETQLKSKYSIRY
                     GPIDGYDGNPFSANFGKSASYLIVYVYFRRSVYYYNPSGSSLGSNTGGSERAWITIDS
                     NKTGFSVHSYDTSYEPYPFTGYYIACFA"
     gene            1857..2147
                     /locus_tag="MIV85_002898"
     CDS             1857..2147
                     /locus_tag="MIV85_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962226.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNSSNRKIQDDTETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKVEASTKQAHLRIDEIINRIGGK"
     gene            2151..2408
                     /locus_tag="MIV85_002899"
     CDS             2151..2408
                     /locus_tag="MIV85_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBY2962227.1"
                     /translation="MDNLISFIPEQLLILVAALYVIGAGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGVNQTYKQFKDGEK"
     gene            2669..3532
                     /locus_tag="MIV85_002900"
                     /pseudo
     CDS             2669..3532
                     /locus_tag="MIV85_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
     gene            3611..4423
                     /locus_tag="MIV85_002901"
     CDS             3611..4423
                     /locus_tag="MIV85_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2962228.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFINR"
     gene            4517..6916
                     /locus_tag="MIV85_002902"
     CDS             4517..6916
                     /locus_tag="MIV85_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBY2962229.1"
                     /translation="MIFKKYIKSLLIVVSVTLIMNKSILFVNALDLESNNNIKSYKRK
                     NVKEIDISNKFVDESFRRDIVEKVLDNRDDPLTNEVASKDNYKIYESDLNKIESCLEL
                     DLHKNPDVSNPNKIDNLDGIENFRNLEKLDCSSNNLESVDLSKNIKLKYLDISGNKIL
                     NINLKNNNLINELHCDANKLSSLDLKNNKNLVSLFFTSNELTEIDLSNNVNLENLQFL
                     NNNLKSIDLSHNKKLKSLNCTNNKLKSLNLSNNVFLKNLSCSGNNLSKLNIKGLTSLE
                     YLGCAKNKLQDLDVSTNIKLDSLFCGKNSLTKIDISKNKELKSLECSGQYIEKSIIKN
                     GENIVVDIGIENSKLKELYPQNYNISTGFLTWKNISEFPNNVSYSLEYEYGPVNDVET
                     MDVNISIDKLVKCRIRYIDYDGSIINEKEISDNSSINEIQINPQRENYEFNGWRNNKD
                     EKIYTSEQVSKLVFDDSTDFIATYKRKSTGSSGSSGGTSSKEDFNIAPSKEKLTGADR
                     NETSVKISQKGWNKADNIVLINDSSISDALSATPFAKSKDAPILLTKNNNLNKLTEKE
                     INRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRISGNDRYETSIKLAKELDKNSNL
                     SKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQNDDMKDIKDLIANKNISKSYVIGG
                     ESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFYSKDTLNDLYVAKNGMNKQDDLV
                     DALSVGVLAGKTESPVVLVGNGLDDSQKELIKNKKFKNITQIGGNGNEKAFNEVENLV
                     K"
     gene            complement(6957..7142)
                     /locus_tag="MIV85_002903"
     CDS             complement(6957..7142)
                     /locus_tag="MIV85_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBY2962230.1"
                     /translation="MILLEQRKLRVAFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            complement(7690..7866)
                     /locus_tag="MIV85_002904"
     CDS             complement(7690..7866)
                     /locus_tag="MIV85_002904"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962231.1"
                     /translation="MEQKESKIVYSKGGSGTYSAKISLPLSQLEKMGFTREKRKAVVI
                     FKEDEIIIKKSDEE"
     gene            8583..9260
                     /locus_tag="MIV85_002905"
     CDS             8583..9260
                     /locus_tag="MIV85_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBY2962232.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            9434..11470
                     /locus_tag="MIV85_002906"
     CDS             9434..11470
                     /locus_tag="MIV85_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBY2962233.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(11661..12227)
                     /locus_tag="MIV85_002907"
     CDS             complement(11661..12227)
                     /locus_tag="MIV85_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2962234.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            12515..13450
                     /locus_tag="MIV85_002908"
     CDS             12515..13450
                     /locus_tag="MIV85_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2962235.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            13915..15129
                     /locus_tag="MIV85_002909"
     CDS             13915..15129
                     /locus_tag="MIV85_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962236.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETMNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(15549..16070)
                     /locus_tag="MIV85_002910"
     CDS             complement(15549..16070)
                     /locus_tag="MIV85_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962237.1"
                     /translation="MKFKRLRTSENKLCYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            16426..17223
                     /locus_tag="MIV85_002911"
     CDS             16426..17223
                     /locus_tag="MIV85_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBY2962238.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGIKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            17333..17923
                     /locus_tag="MIV85_002912"
     CDS             17333..17923
                     /locus_tag="MIV85_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBY2962239.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            17989..19686
                     /locus_tag="MIV85_002913"
     CDS             17989..19686
                     /locus_tag="MIV85_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBY2962240.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            19900..20739
                     /locus_tag="MIV85_002914"
     CDS             19900..20739
                     /locus_tag="MIV85_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBY2962241.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
BASE COUNT         8499 a         2186 c         3416 g         7029 t
ORIGIN      
        1 gttaagtata agtaagaata taatgccact gcccgaaaat gtaaatttaa atgatatatc
       61 aacaaaatta gttgaggtta atgcaggatt taaagttggg aaaacaagta ttataaacac
      121 tttagcactt aaaaatatag aagcaagttt aaataataca cttgtggagt tatcagagaa
      181 aataaaaaca agttttgata gttcagacac tagtgtgcaa gatttacaaa atcaagtaac
      241 acaaaaaaac aatactataa ctcaattaga aacagagtta agtaaaagaa aaagatttat
      301 aacaggaact tatacattca caaaaacgga tgcagagaat tttaacttaa gtatatatga
      361 caaagaagga acttcaaaaa ctcttactat accagttaac atgggcttct ctcctagttt
      421 aattgtactt agtggagtaa cttttagtac aacaagtaaa tcttatgttt attttgataa
      481 tgtttgtaat tcaaattttt ataattttgg ctataattct gattctactc atagtaaccc
      541 gaaagctgtt ggtattctta atgtatctaa tgttgggtat tcttcattag tgcttacatt
      601 atataaatta tcaatgtcag aagcagttgg aatatgggca aaagagggag ctacattaac
      661 ttacaaaata tatatttaat aaaaaaatga ggtgataata tgaacagaaa taatagaata
      721 atttacgacc aaacaggcaa tatatggctt caaactggtg aagcaacagg agatatacaa
      781 gagtggtcaa aaataactga attaaatttt ttggatgttg aatttggtag tatagactat
      841 agtaaacaat atatagagtc tataaatcca gttacaaaag aaccaatcat caaagacata
      901 gaagtcattt taacagatga acaaaagaga ttacaagcat tagaaaaaga attaagcatg
      961 ttaaaagaag aaaataaaaa tagagatagt gagatagtaa acacagcctt tgaggtagaa
     1021 aatataaaat taaataacaa tttataggag gaattaacat gtataactta ttaaaactta
     1081 tgatagaaca aaagaactat agcactaaag aggatttgca acacaaaatt gatgtattct
     1141 atgcagtaaa tagaattaca gaagaacaat atttagaact tacaagttta ttaaataaag
     1201 aagaaacacc agcagaacca ataaaatagg ttcttttttt attgaaagaa ggtgactaaa
     1261 tgacttttaa agagttagtt aataaagtta gaaatcttgt attagaagca aagaatgtaa
     1321 ctatagaaga tacagaaagt aaatttacaa gtgaaaatgt agaaggagca ttgaaagaat
     1381 gtatagatag agcagatgag gcttttcaag aagccgatag tggaaaaaca cttttatcaa
     1441 ctgctatcgg ctctcctgct acatcagaac aaacatttca agattatgcg aactatatta
     1501 caggatttaa gagcaatata agcaatttag aaactcaatt gaaaagcaaa tattctatta
     1561 gatatggtcc tattgatgga tatgatggta atcctttttc tgctaatttt ggcaagagtg
     1621 caagttacct tattgtctat gtttacttta gaagaagtgt atattattat aatcccagtg
     1681 gtagttcttt aggaagtaat acaggaggtt ctgaacgtgc atggattact atagacagca
     1741 ataaaactgg tttttcagtt cattcatatg atactagtta tgagccatat ccttttacag
     1801 gttattatat tgcttgtttc gcataataaa ttatattatt aaaactagga ggatgtatgg
     1861 aagaaattag cataaatcta ttatgtgcag ttgcaggagt tgtaatatcc tacttagcat
     1921 ttagaaatag ctcaaacaga aagatacaag atgatacaga aacaactaca aaattagaac
     1981 aacaaataac ttttctgtgt gagaatgtaa gagatataaa gcatgatgta gcaaagttta
     2041 atacaagttt cttagatatc agtgaacgag ttgcaaaagt agaagcaagt acaaaacaag
     2101 cacatcttag aattgatgaa attataaata gaattggagg aaaataaaag atggataatt
     2161 taataagttt tataccagag cagttactaa ttttagtagc tgctctttat gttataggag
     2221 caggttgcaa aaaatataaa caattagata ataaatacat tccagtagtg ttattgatac
     2281 ttggaatagg tttctcaata tggatgctag gattaaatcc tgttgcagtc ttacaaggtg
     2341 taatttgttg gggagttgca ataggtgtaa atcaaactta caaacagttt aaggatggtg
     2401 aaaagtaatg aaattaacaa aaatattatt actcacaaaa atttaaaaaa tttcattaaa
     2461 tagagtatac ttttatagct aataagtata taataatagt acagaactcg taaagcattt
     2521 atatgctcaa atatacggga cattgatttt tgaaggaacc cgccaagctt cttttatagc
     2581 tcaaatagtc gggacagata aatttaccca ctaatattaa ttggtgggtt ttattatata
     2641 aaagtatatc tatgaaaagg tgaaaacaat ggttgaagta aaagaagaaa aaacatttga
     2701 tgaacaaata gatattttaa aaagtagagg attaataata aatgataaag aagatgctaa
     2761 atttgtatta agtaatgtca attattatag gtttacagca tatcttctaa gttttaagaa
     2821 tgatgatggc tcatataaag aaggaactac gtttgaagaa gtttatgata tatataggtt
     2881 taataaggaa tttaggatat tattaacaga tttgttaggg agcatagaaa tagcatttag
     2941 gacatacatt gcatatacat tagcaattaa acatggtgct tgtggatatc tataaaggga
     3001 gagtttcaaa gatgaaaaat tctatattaa ttttttgaca gcattagaga gagaaaaaaa
     3061 taataattca gataagcttt ttattataca ccataaagaa aaatataaag gaaaacttcc
     3121 catttgggtt gcaacggaaa taatgacttt tggtatgttg taaaaattat attcaaacat
     3181 gttgccagaa gatactagat acataaaaaa taatttgtgt agagtgaata ctttattagt
     3241 taaatcttgg ttacaatcat taacacaggt cagaaatcaa tgcgctcatt atggtagaat
     3301 atataataat aatttccgta ttataacaat aaaaaacgaa tataaaaagt ataacttgga
     3361 taataaaaag atattttctt atatacttgc tatgaagcat ttgactatgg ataaattaat
     3421 ttggaatagt ttttttataa aacttcaaaa gttaattaat gattataata attctataga
     3481 cttaaagctt attggttttc ctaataattg gatagagata ttggctaaat aaaatagtta
     3541 ctttaagaag tttataaaca cttactatat gtaagtgttt ttttattgaa aagaaggagg
     3601 aaaataaata atgaaaatat gtattacagt aggacacagt attttaaaaa gtggtgcatg
     3661 cacttctgct gatggagtag ttaacgaata ccaatacaat aaatctcttg caccagtatt
     3721 agcagataca tttagaaaag aaggtcataa ggcagatgta ataatatgcc ctgaaaagca
     3781 gtttaaaact aaagcagaag aaaagactta taaaatacct agagttaata gtggaggata
     3841 tgatttactt atagaactac atctaaatgc aagtgatggt caaggaaaag gttcagaagt
     3901 tctatattat agtaataaag gtttagaata tgcaactaga atatgtaata agctaggtac
     3961 agtatttaga aatagaagag ctaaattaga taaaggatta tatatcttaa atagttcaaa
     4021 tcctacagca gtattaattg aaagtttctt ctgtgataat aaagaagatt atgagaaagc
     4081 taagaaacta ggtcatgaag gtattgctaa gttaattgta gaaggtgtat taaataaaaa
     4141 tataaataat gagggagtta aacagatgta caaacataca attgtttatg atggagaagt
     4201 tgacaaaatc tctgcaactg tagttggttg gggttataat gatgggaaaa tactgatatg
     4261 tgatataaaa gattacgtgc caggtcagac gcaaaatctt tatgtcattg gtggtgcagc
     4321 atgtgagaag attggttcta tgactaaaga aaaatttact atgataaagg gtaatgatag
     4381 atttgataca ctttataagg cattagattt tattaataga tagattatat aaaatatttt
     4441 agtatttctt gaaaatcata agtatggtaa tatttagata aatattattt attattaata
     4501 ggtatggggg tagattatga tatttaagaa gtatataaaa tcattactga tagttgttag
     4561 tgttacattg ataatgaaca aatcaatatt atttgtaaat gcattagatt tagagagtaa
     4621 caataacata aaatcttata aaagaaagaa tgtaaaggaa attgatataa gcaataaatt
     4681 tgttgatgaa tcctttagaa gagatattgt tgaaaaggta ttagataata gggatgatcc
     4741 attaacaaat gaagttgcat caaaagataa ctataaaata tatgaaagtg atttaaataa
     4801 aattgagagt tgcttagagt tagatttaca taaaaatcca gatgtttcca acccaaacaa
     4861 aatagataat ttagatggga tagaaaattt tagaaatcta gaaaagcttg attgtagttc
     4921 aaataatcta gaaagtgtag atttaagtaa aaatataaaa ttaaaatatc tagatattag
     4981 tggaaataaa atattaaaca ttaatttaaa aaacaataat cttattaatg aattacattg
     5041 tgatgcaaat aaattatcaa gtttagacct taaaaataat aaaaatttgg taagtttatt
     5101 ttttactagt aatgaattaa cagagataga tttaagtaat aatgtgaact tagaaaattt
     5161 gcaatttctt aataataatt taaaaagtat agatttaagt cataataaaa agttgaaatc
     5221 tctaaattgt actaacaata aacttaaatc tcttaattta agtaataatg tttttttgaa
     5281 aaatttaagt tgttcaggta ataacctaag taaattaaat ataaaaggac ttacaagtct
     5341 tgagtatttg ggatgtgcta agaataaatt acaagattta gatgtatcta caaatataaa
     5401 attagattct ttattttgtg ggaaaaatag tttaacaaaa atagatataa gtaaaaataa
     5461 agaattaaaa tcattggaat gtagtggtca atatatagaa aaaagtatta taaaaaatgg
     5521 tgaaaatata gttgtagata taggaattga aaattcgaaa ttaaaggaat tatatccaca
     5581 aaattataat atctcaacag gttttctaac atggaaaaat atttctgaat ttccaaataa
     5641 cgtaagttat agtttggaat atgaatatgg tccagtaaat gatgtagaga ctatggatgt
     5701 aaatatatca atagataaat tagttaaatg tagaatcaga tatatagatt atgatggaag
     5761 tataatcaat gaaaaagaaa tatcagataa ttctagtata aatgaaattc aaattaatcc
     5821 tcaaagagaa aactatgagt ttaatggttg gagaaacaat aaagatgaaa aaatatatac
     5881 atcagagcag gtaagtaaat tagtttttga tgatagtact gattttatag caacttataa
     5941 aagaaaatca acaggatcaa gtggttcttc tggtggaact tcaagtaaag aagattttaa
     6001 tatagcacca tctaaggaaa aattaacagg tgcagacaga aatgaaacat cagtgaaaat
     6061 aagtcaaaaa ggatggaata aagctgataa tatagtgtta ataaatgact ctagcatatc
     6121 ggatgcttta tcagcaacac catttgctaa gtctaaagat gcaccaatat tacttactaa
     6181 aaataataac ttaaataaat taacagaaaa agaaataaat agattagaag caaaaaatgt
     6241 gtacatagtg ggtggattaa agtctgttga tgaaaaagta gtgtctgatt taaagaaaaa
     6301 aggattaaat gtaattagaa tatctggaaa tgatagatat gaaacatcaa taaaacttgc
     6361 aaaagaatta gacaaaaatt ctaacctgtc aaaagtagta gtggtaaatg gagaaaaggg
     6421 actagctgat gcagtaagta tgggagctat atcagcaaaa gaggaaatgc caattcttct
     6481 tactaatcaa aatgatgata tgaaagatat aaaagactta atagctaata aaaacatatc
     6541 aaaatcatat gtaataggtg gagaatcttt atttaataat aaagaagtga ataacacatt
     6601 accatctgta actaaaatag caggttctga tagaacagaa actaactcaa aagtaataag
     6661 tcatttctat agcaaagata cacttaatga cttatatgta gctaagaatg gaatgaataa
     6721 acaagacgat ttagtagatg ccttatcagt aggagtgctt gcaggtaaaa ctgaatctcc
     6781 agtagtatta gttggaaatg gattagatga tagccaaaaa gagttaatca agaataaaaa
     6841 gtttaaaaat ataactcaaa ttggtggaaa tggaaatgaa aaagcattta atgaagtaga
     6901 aaacttagtt aaatagattg aaaggtagta actggaaata gttactacct ccttttttat
     6961 tcattttcag ttttttcaat aattattttt ccatcctcaa aagtaacaag aacatccctt
     7021 tcatcaggag agatattcat ctctttaatc catgacattg gaagtatcaa tctgggtgta
     7081 aaagagcctt tgccactttt attgaatgca actctaagtt ttctttgttc caataatatc
     7141 attcctttct actattaata aatgccagca ataataaagt aaataccaaa gcaataagag
     7201 ctttaaaagt aaaacttatt attatattaa taatatttaa aactatagtg ataccaagaa
     7261 taatcataca aattctataa aatttattat tcatattaaa ttagaaaatg tgttataata
     7321 ttagaaagaa gctacctaga aggaaggtat tttcctccta ggattgaaac ttataattct
     7381 ttaatcaatc ttagtattgc gagtactaga ttaattaaaa ctaatgtgaa agagaaagca
     7441 tttttaattt tattaaattt gttttctctt ttattttttc ttctttctaa tctccccact
     7501 ttctttgtcc tcccttctaa gttttttatt ttcttacctc ctttctatat ttatattata
     7561 tcatcacgtg acgtgaaagt caataaatat tccatatttt tcaataaagc tataaaatat
     7621 attaatataa aatacaaaat ataataaaaa taagtggatg tttacattat acacccactt
     7681 attttagagt tattcctcat cagatttttt tattataatc tcatcttcct taaaaataac
     7741 tacagcctta cgtttttccc ttgtaaatcc cattttttca agttggctta aaggtaaaga
     7801 aattttagcc gaataagtac ctgaaccacc tttactgtaa actattttag attctttttg
     7861 ctccaaacta ttttcctcct tttttatatt gtaatgtaac aaatattaac aataaaatgc
     7921 ttactattaa tcctattata ttgttgatat taaaatgtaa aaataaaagt attatgtcta
     7981 ttactatagt tatagcaact ataataagac agaatttata aactttatca ctcatatttt
     8041 atagaaaatg tgttataata tttagaaaga agtcactagg aagaagatta aattcttcct
     8101 agcttacaaa actataaatc ttttaataat ttaattagtt tatcaattaa atttattaaa
     8161 atgggtaaga tagagagagc agttttaact ttggcgagtt tgctttctct atcttttttt
     8221 cttctttcta ttctactcat tttccttttc accccctttc tatatttata ttataatatg
     8281 ccgaaccggc aaaagcgata tttatttcca tatttttcaa taaagttata ttgacaaact
     8341 atattttttt acaaataaaa ataagggtgg caaaaccaaa cttgccaccc ttttgccacc
     8401 gaaaataaat aatagaataa atttaaatta aacataataa aacataaaca acaaaactga
     8461 ccttaataaa acattgaaat accaacactt gtaaaaaata acaacaataa acaaataacc
     8521 tagaataata ttacaactta agtaaataat aattttgaat aataatttac ggaggtattc
     8581 atatgtttaa acacgataaa gcattattaa aagaagtaaa agtagaaaga ccaaatcctc
     8641 aatatgctgt tttaatgcaa gaacagttgg gtggtgcaaa tggagagtta aaagcagcta
     8701 tgcaatactt gtcccaaagt tttagaataa aagaccctca aataaaagat ttatttcttg
     8761 atatagcagc agaagagctt agccatatgg aaatggtagc acaaactata aatttattaa
     8821 atggacatga tgttgattat aattcagtta atacaggcga aatagaaaca catgtattaa
     8881 ctggtctatc accagtctta ataaactcat caggagctcc ttggactgct aattacgtta
     8941 cagttacagg ggatttagta gctgacttac tttcaaatat agcttctgaa caaagagcta
     9001 aggtagttta tgagtacttg tatagacaaa tagatgataa atatgtaaaa gaaacaatag
     9061 atttcttact taatagagaa gaagcacata atgctctatt tagagatgct ttaaataaag
     9121 ttaaagatac aggttcaaat agagattttg gagttacaga agattctaaa ttatatttcg
     9181 atttgtctac tccagggcca aatcacgata ctaagataga tattaatcct ccttcttttg
     9241 aaaaaccttt aaaaaaataa tttgatattt tttatgttgt tttgttttag tagttataaa
     9301 aattatttac taggagaatt aattatatga aaaattaaat atgtatggtt aaaaatgggt
     9361 atacacttat tataagtgta tatctatttg tttattgcaa aacatataat aaaataacaa
     9421 atgaggtggt attttggaca gtaatagaaa acctaataat ctaataaatg aaaaatctcc
     9481 atatctttta cagcatgcat ataatcctat aaactggtat agttggaatg atgaggcttt
     9541 taaaaaagca aaagaagagg ataagccaat atttttaagt gtaggatatt caacatgtca
     9601 ttggtgccat gttatggaaa aagaatcttt tgaagatgaa gaagttgctg aaataatgaa
     9661 tagaaacttt gtggcgataa aagtagataa agaggaaaga cctgatgtag atagcgtgta
     9721 tatgacagtt tgccaagcca tgacaggtag tggtggatgg ccaatgacca taataatgac
     9781 accagataaa aaaccttttt ttgcgggaac atatttccca aaatattcaa ggtataatag
     9841 acctggagtt atagatttat tagagaatgt atctgaaaag tggaatacaa gcagggatat
     9901 attaataaaa tctggagatg aaataataga agctcttaag gatgattttg gtgtaaaaaa
     9961 tactgagggt gatttatcaa aagagatgtt gagttcatca gttagagtat ttaaggctat
    10021 ttatgatgaa aagtatggtg gttttggtaa tgctcctaaa tttccaagtc ctcagaatct
    10081 tatgttttta atgaaatatt atagtataga aaaagacaaa gatgtgttaa aaatggtgga
    10141 aaaaacttta gatggaatgt atagaggagg cttgtttgat catattggat ttgggttttc
    10201 aagatactct actgataaaa agtggttggc tcctcatttt gaaaaaatgc tatatgataa
    10261 tgctatgctt actatagctt ttttagatgc gtataaaata acaaagaaag agttatataa
    10321 agaaattgct ataaaaacta tagattatgt agttagagag atgaaggata aagaaggtgg
    10381 gttttattca gcacaggatg ctgatagtga aggtgaagaa ggtaaatttt atacatttaa
    10441 tcctcttgag ataattgaag ttttgggtga agaagatgga attttcttta ataattattt
    10501 tgatataact agtagtggaa attttgaagg caaaagtatt cctaatctta taaaaaataa
    10561 agaatatgag agacataatg aaaagatagc tgaccttagt aaaaaggtat ttgaatatag
    10621 aaaagaaaga acatctttgc ataaagatga caagatactt acatcatgga atgcattgat
    10681 gatagttgct ttaacaaagg catatagtac tttaaaaaat gacatatatt tagagtattc
    10741 aaataagtgt cttaacttta taaataataa tcttgtaaat gagtcaggta gattattagc
    10801 tagatataga gatggaagtt ccgactattt agcatattta gatgattatg cttttttaat
    10861 ctgggcgtat atagagcttt atgagtcaac atttaatatg aaatatttag aaaaggcttt
    10921 aaatttgaat gaaagctgta tcaacctttt ttgggattat gaaaaaagtg gattttatat
    10981 atatggtaaa gatagtgaaa atttaatagc aagaccaaaa gatttgtatg atggagctat
    11041 tccatcagga aattctgttc aattatacaa tcttataaga cttgcgaaaa ttactggaga
    11101 taatagactt gaagaaatgt catataaaca attaaaactg tatgtggata atgtaaagag
    11161 ttctccaact ggctacagct tttatatgct ttcattgatg tttgaacttt attctactaa
    11221 ggaaattata tgtattttta aggaagattc tgatttaatt gcatttaaag aattgataag
    11281 tgaaaatttt ataccaaatg caactttttt agcaaagaaa tacaatgaag aaaacactat
    11341 tataggtttt ttaaataact atatattgaa ggatgataag actagttatt acgtgtgtca
    11401 aagtaatagt tgtagtcaac caattaatga tttacaaaaa ttaaaagata tgattttagg
    11461 agtagaataa tcataatagc gaaaaaggag atgctttaaa ataaaagtct aatcatctcc
    11521 tttttttgta taaaaaacag aaaaagagtt cctaagaaca cctaatctat gtaatgattg
    11581 ttttgttaaa aaataaaaat gacattatag ttatataaaa tattgtacta taaaaaagtg
    11641 gtattataga tgcgatagta ttaatctttt ttatttaccc tatttcttct ttttgcaaat
    11701 tcttcaagtg cttcagattt aattttatct atttcttcat attccataaa attagcatct
    11761 tcttcaaagc catcttgttc ttcaccatta aaacgataca ttttttttag taaactccat
    11821 aaggtctcta attcatcttt ggtaaattcg tgaaatacat ctgccataaa gtttattcca
    11881 gtcctactac atgttaccat aacctttttt cctaagtctg taactttaac attaattgct
    11941 ctcttatcat gaggacttgg aattacatca acatatccat ttttttcaag attagcaact
    12001 agtctattta tattttgttt acttgtaccc atttttcttg caatattatt taatgttgtt
    12061 tcttcctctg gtaaatgaag aattgataaa atagtcatat actgtcttga agtaagtata
    12121 ccaaaatatt tatctccttc tatttgtatt ttgtttgtaa gggtaaaaag agttgcatat
    12181 gtttgattca ttaaaaagag ctcttttagt tcatttgaat aatccatgaa atatatctcc
    12241 tttattttta gatgttgttt tgtcgaaaac agaatatcat gaattaattc taatgtcaat
    12301 atggtgtcaa aatatattaa agtattactt ttttatgtaa ctattaatta attaaattat
    12361 tgtataattt tatgtaaaaa cttctatgta ccaatgataa tttctatgag gaattaataa
    12421 ttcttaaatt ttttagaaag attttgactt gaaaatactt gtaatataat atataaatta
    12481 atatactgaa taaaatcaat ctggagggat aattatgaag tgtacaaact ttactttcaa
    12541 aggagaggaa ggtttagata tatatacata taaatgggaa gatgaaaata taaaaaaacc
    12601 aaaggcagtt atccaaattg cacatggaat ggctgaaact gcacaaaggt atgagacttt
    12661 tgccaaggta cttactaaaa atggttatat agtatatatc aatgaccata gaggtcatgg
    12721 aaaaactgca aagataatag aaaatgttgg acatttagct gaaaaagaag gatttagatg
    12781 tcttgtagag gacatgtata ctttaacaaa tattataaag aaagaaaatg aagatttgcc
    12841 aatttatcta tttggacaca gcatgggttc atttgcaagt caaagatata taatggatta
    12901 cagtaataat ttatctggtc ttatactatg tggttcaaat ggaaagcaag gaatcattct
    12961 aaatcttgct catctgataa tcaatcgtga gattaaaaag tatggaagac gttctaaaag
    13021 taataaaata aataatttga tatttggtgg cgaaataata agaagaaatg aaaagactaa
    13081 gtttgactgg ttaagtagag ataaagaaca agttgaaaaa tatataaatg acccattttg
    13141 tggagtagtg tgtagttgtg gcttttttta tgatttagtt caagggttaa aagaaattga
    13201 ggataaagaa aacttaaaaa aagtgccact tgatatacct atttacataa tatctggaga
    13261 taaagacccc ataggaaaaa atggtaaagg agtcttaaga ctaagggata gatatataaa
    13321 attaggagta aaagatgtaa cttgcaaact ttacaaagat ggaaggcatg aattgttgaa
    13381 tgaaataaat agagaagaag tttttgagga tataatttgt tggttaaata ataaaataga
    13441 aatattgtaa taaaaaaata taatgatata tttgctttaa atttatttat atataatatt
    13501 tgaaaagtgg attatgtata tgcaaagtag aaaagagaga gcctagaagt gattttttgc
    13561 tataatgcca tttattgaat aggtgggtgt tattataaat aaattattaa cactcagtat
    13621 gattatcatt gtatatggaa tttattttat ttaaaattcc ttgaaagttt aaatatagta
    13681 agttgtaata aagagaaaat ctaaatattt aaatgctatt taatgtgaat ctattaatta
    13741 ggttatactt aaacttaatt aatagatttt atatttcaag ccaatgagat agggttttag
    13801 attaaaatat aaccaatggt taaattacag acattttgtt aactttccct cgatttacta
    13861 gtaaatattt tttttatata cttaaattac aacagatgta ctagggaggt atatatgcaa
    13921 attaaaatag gtaaagtcat acagtgtctt agaaaagaac gaaatttaac tcaagaacaa
    13981 ttagcaaagt ttataggtgt gtcaacacca gcagtatcta agtgggagag tggaaattct
    14041 tacccagata tagaattatt gcctttatta gcagactttt ttaatgtgtc tattgataag
    14101 cttttaaatt acaagattga tttaagtgaa gaagaagtaa tgaaaattta taaagaatta
    14161 gaatcaggct ttgctagaat tgaaattgat ttatcaacag aagaaccaaa agaagaattt
    14221 agacaagact tagaatctgt aaaaaagctt tccaatatgt atatagagaa gtatcctaaa
    14281 agctatttat tgaagctaag gatatgttcg ctgtatcaga tgtattcata taaatttggt
    14341 aagagtgaac ttaatgacag agtaaaagaa acaatgaata ttcttgaaga tatagtgaga
    14401 aatacagatg atatccaaat aaaagaaaca gctcttatta tattatcaaa cgcatattgt
    14461 atgttggagg attatgaaaa ggcagagttg tatttaaata tgatacataa gtcaataggg
    14521 gatacaagtg ttaatttagc tatgatatat ttaaagcaaa atagacttga agaagcagaa
    14581 atattgcttc aaaataaatt gtttagtaat gtatttaata taagcatgga ttgtaaggga
    14641 ataattaatg tatacaaaaa tcaatacaag gaattaaaga aaaaattgga gaatagaaat
    14701 tttaataaaa atgcaattga gagagaaatg gagtatataa aaaataagtt gctggggtat
    14761 gcaaatcttt ctttagaaat aaaaaaaatg ctcagtgaag ataaaggtgc attttttagt
    14821 atgtatatgg attatatgga attatctcta atttttttat tttttaacat gaaagaagaa
    14881 gcaaaaaaag ccttatatag tctaaaagaa atattagaaa aatatcctat acatgaaagt
    14941 ttggatgtaa gtcaaatgag attttttgat aaggtagagt ctaaaaattt atatactttt
    15001 aatatatata caaacttgtt aattgtactt aatgatgata gttataatga gcttagagaa
    15061 gaaccaattt ttaaggatgt aattgaaaag attttagata tggaaaaaat gttgaaaaat
    15121 aaagaataag taaaaattta atataggact taaagattaa tcaaattaaa agaaagtgtt
    15181 tcaaaataaa aatttgaatc accttttttg tcggtcttaa acagttattt agaaaaatag
    15241 aggtttcaaa atagaaatct gaattatctg tattattaca caaaaataga aacctaaatt
    15301 tataaaaata gaataaagtt tgttatataa aatgtaattt tgtctataaa atctcacttg
    15361 ttttcttaac tttaagcgtg aaaaagagaa tgtatcatga attttttagt tcatgatgca
    15421 tccttctttg tatgaaatcc aatatatctt tattatttaa acaatggaaa agagccttat
    15481 ttctattttg agacatctct tttatttaat tatgaagttt tatacagttc aataaatagg
    15541 aattatattt agaaactcat gacattattt cttagatagt gattaaattt atcatattcc
    15601 attttagata acttttctgg gtaagacatt acaatcaggt tatgcccatt aaatttttca
    15661 tggtatggtg gatgaatgtg ttcataatta tttgtcttat attttactct ttcatagaac
    15721 gccttgcgat aaattgaaat ctcatcaatt ggaaggtcaa tttctaaaat aatagttttt
    15781 cctttcttat ttaaaagctc taacgctctt tgtccatatc tattattgcg catttctgga
    15841 aaaatgcaga aatgttctac atagataaag tcatctgttt cccaacataa aattatgccg
    15901 acaaactggt ttttatcata aattaaattg aactgatatt ctttattttt caaaatttct
    15961 tcttgcaaag aagattttct ttgttcatga aatgggaaac taattttata taattccata
    16021 gccttgtaac ataatttatt ttcactggtt cttaaccgtt taaatttcac tttactcctc
    16081 ctaatcacga aaattccaat ttatttatga gttcatttta ccatagtcag tatttgcata
    16141 caatgtgttt taagttgagt gtcatttctt tcttttattt atgcttatat ctcatagact
    16201 aagagataat tgcttaagac ataactaaaa actattatat taagctttga taatctaaaa
    16261 acagtatatt tatggacttt tctaggtcta aaagtaatct taataatttt agaagttaca
    16321 aaaaagttac ataaatttgg aaagctataa tatacatata taatataagg ttaaaactgt
    16381 aatgaataat attaatttaa aatttgaaca tggaaggaga ttattatgga gaaaagagaa
    16441 aagaggataa taatatcatc tttattaagt gtatcaattt taatgggttt ggtaagtata
    16501 tattctatat taaataaaga agacataatt ttaactgtta agggtcaaga gcaaaaagta
    16561 tcttccttta agaaaacagt tgaggaactt ttggatgaac agggtataaa gtataattct
    16621 gaagataaga ttaatccaag tttagataca gaactaaaag atgatatgaa aataaaagtt
    16681 gttaaggtaa ctaaaagtaa aaaagaagag attgaaaaaa ttccatttga tacaaagcat
    16741 gtaaatgata gtaatttgtt aaaaggaaaa tctaaagttt atcaagaagg tcaagaagga
    16801 gaaaaaaaac tagtctataa tttaacttac catgatggaa agttagtcaa aaaagtctta
    16861 tcaaaagaag taatatctaa ggagccaact acaaaaatta taaaatatgg aactaaagaa
    16921 aaagtactaa tagcatcaag aggagcaaat ataagaggag gcaaacatat gaaagtggtt
    16981 gccactgcat atgcaggaga tacaataaca tctactggta caactccaag atggggtgtt
    17041 attgcagttg acccacgtgt aataccatat ggaacaaaag tatatatacc taaactgggt
    17101 atgacttttg tagcagaaga ttgtggaggt gcaattaaag gtaatagaat agacattttt
    17161 atgaacagtg aaggaaaagc ttcaaattgg ggaaggaaaa gtatagatat atatctacat
    17221 taaattagtg aatagaataa ctttacttga aggacaaaaa agtataaaat atgaattaac
    17281 taaactgtta gattattctt aaaacataaa aatatatcta aggggggata agatgaaaat
    17341 agtatgctta ggagacagtt taacgtatgg atttggagta tcacgaagta attcatggac
    17401 aaacattgta aataaagaga ctcgattaga aatagtaaat aagggtataa atggtgatac
    17461 aacaagtggt atgttagcta ggtttaatga agatgttgta aaaaattctc ctgatatagt
    17521 ttttataatg ggtggcacca atgattttat tgctggtgcg ggaaatgaaa ttattaattc
    17581 taatataatg gctatggtgc atcagtcata ttcaaaaaat attataccta taataggtat
    17641 accattaaaa ccagatattc caaatgttag ggaagattgg agttgtttta ctgattttaa
    17701 tatagtatct caaaacttag aatcatatag ttattggata aaaaaatttt gtatgacatt
    17761 taatactaat ttcgtagatt tttattcaga atataataaa aatatggaac tagaaggata
    17821 taaaaaatta tattttgatg ggttacatcc aaccaaagag ggtcatagaa taatggcaga
    17881 catttttatt aattcaatta ataagtatat agaagagtta tagattacat taaaatgctt
    17941 gtttatgcgt cagttgcaat aaatacatac agtagagagg ggtttattat ggattatact
    18001 aaaacttatg aagagtggat aaagggttca tattttgatg aagatacaaa gctagagttg
    18061 gagaatataa aaaataatga aaaagaaata gaggatagat tctataagga tttagaattt
    18121 gggactgcgg gtcttagagg aataattgaa gcaggaacga atagaataaa taagtacaca
    18181 gttagaagag ctacttttgg attggcaaac tatatattag aaaacacaac aaaagaagaa
    18241 acaagtagag gagtagtaat agctcatgat aatagacaca agtctagaca attctgtata
    18301 gaatctgcaa atactttggc agcatgtggt ataaaagcat atatatttga tagtttgaga
    18361 actactccag aattatcttt tgctgttaga agcttaaatg caatcgctgg tatagtcata
    18421 acagcaagcc ataatcctcc agaatataat ggatataagg tatactggga agatggagca
    18481 caagttatgc cagagattgc aaatgcaata acagagaaag taaatagtat acatgattat
    18541 agtacaatac caaccttaac ggaagctaat aaaaatttgg tagttttgtt ggacgaatca
    18601 caagatacta aatttataga agcagtgaaa agccaaatta taagaaaaga tttagttaaa
    18661 aatgtaggta aaagctttaa gatagtttat acacctcttt gtggaacagg gaatgttcca
    18721 ataagaagag cattgaaaga agttggtttt gaaaatataa ttgtagttcc agaagaagaa
    18781 aatccagacc caaattttgc agggcttgat tatccaaatc cagaagagaa aaaagcttta
    18841 aatagaggta tattactcgc aaaagaaaaa ggagcagacc ttgtaatagc aactgaccca
    18901 gattgtgata gagtaggtgt agcagtaaaa actactacag gtgagtatgc tttacttaca
    18961 ggaaatcaaa ttggtggtat gctgacacat tatataatag aaggattaaa agaaaataat
    19021 aaattaaaag aaaatcctac aataataaaa accatagtta catcagaatt tggagcagat
    19081 atagctaaag caaataatgt tgatgtatta aatgttctta caggttttaa atttattggt
    19141 gaaaaaataa aattatttga acaaaataaa aatagaagtt atgtatttgg atatgaagaa
    19201 agttatggtt acttagttgg gactcatgct agagataaag atggtgtagt ttcttcattg
    19261 ttaatatctg aaatggcagc attttactat tcaaaaggta tgagtttata tgatggttta
    19321 atagaacttt ataaaaagta tggatttttc aaagaacaga ctatatcttt gactttaaaa
    19381 ggtatagaag gtgtagaaaa gataaaagaa ataatatctt attttagaga aaatcaaatt
    19441 gattatataa atagtattaa agtagttgat aaaaaagatt ataaaaatgg tatagataat
    19501 cttcctaaat ctgatgtttt aaaatacttt ttggaagatg aatcttgggt agctataaga
    19561 ccatctggaa cagaaccaaa acttaaattt tacatagctg taaaaggagc tagtgatatt
    19621 gaagcagata aaaagattca aggtttgaaa aagtatatag atgacatggt cgaaaaatta
    19681 aaataaaata ttattatttt ataagataat tttgtaataa tatttattta gctgaaaatt
    19741 ataatttact ttcattgagt agaatatgga aatgttagta gaattgttat tttcagcttt
    19801 tatttgtgtt atttttactt aaataattat attatagaat gaatctgagt ataattaata
    19861 ttgtataatg aaattaattt gatagaaaag gggatattta tgtttggtat agataagaaa
    19921 ttgattgaat atataattgc aaaatccaat tacagtgaat taagttcaaa gtcagcagaa
    19981 gtatctttct tcttaatgtt gtccatattt ccttttttaa tatttacaat aagttctata
    20041 gcttatatac cgattcttca tttaaataag tatatagctt tgtttagaaa tatgatgcca
    20101 gaaggtgctt ttgctgtgtt atcttcaatc atagtttctg caatagacaa tagaaacctg
    20161 aaatttttag cagtcagttt tgtacttact atgtggacat tttcaagagc agtaaaagct
    20221 cttattaaag gaatgaatag agcctataaa gttaaagaaa ctaggtcttt ttttaaaatt
    20281 ttatctatat catttttatt tacaataatg cttttggtcc ttattttttt atctatgata
    20341 tttttagttt acggtgaaaa aataggttat tttattttta atcttgtagg attggatgag
    20401 atatttataa aaatatggga tattctaaga tacactgtag gtataataac aataatagtg
    20461 atatttacac ttttatataa atacactcca aataaaaagt taactattaa agaatctgcg
    20521 ccaggtgcta tttttgctac ttttgcttgg tttttagtat catttttata ttcttattat
    20581 acaaattact atgctaacta tgaagtaatc tatggaagta tagctgaaat aattgtactt
    20641 atgacctgga tgtattttag tagttggtct atcgttattg gctatgaggt aaattcaaga
    20701 ttgtatttta gaaagataag acatgaaatg ttaaagtaaa gtatttaaaa taaaagagag
    20761 tatttagtat tataaatgta attgaattaa taaagaaata ttgacattta agttaaaaag
    20821 tctagaattt ttctgggctt tttttatttt tagtataact tgacaaattt tatttaatgg
    20881 gatagtttta atttataatc atctttaaaa agatgactat tgataagtaa gagataaaat
    20941 tggtaagtat caaaaaatat actaaataaa aattatagtc ctaatgagtt aatttctgta
    21001 ttttcaaata atgcagtatt tagtcatgtg tttttatatg cgcctgtatt tctaattagc
    21061 aatatattag aataagctac tgtaattaga tttagaaaaa agcgacataa ataattataa
    21121 acaaataata
//
LOCUS       DAGQVA010000072        20564 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.072, whole genome shotgun sequence.
ACCESSION   DAGQVA010000072 DAGQVA010000000
VERSION     DAGQVA010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20564
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.072"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            344..1237
                     /locus_tag="MIV85_002915"
     CDS             344..1237
                     /locus_tag="MIV85_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBY2962242.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1237..2631
                     /gene="gltA"
                     /locus_tag="MIV85_002916"
     CDS             1237..2631
                     /gene="gltA"
                     /locus_tag="MIV85_002916"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBY2962243.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            2997..5216
                     /locus_tag="MIV85_002917"
     CDS             2997..5216
                     /locus_tag="MIV85_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2962244.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5363..6109
                     /locus_tag="MIV85_002918"
     CDS             5363..6109
                     /locus_tag="MIV85_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962245.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6109..7989
                     /locus_tag="MIV85_002919"
     CDS             6109..7989
                     /locus_tag="MIV85_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962246.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKNYTRKVWF
                     FD"
     gene            8108..9499
                     /locus_tag="MIV85_002920"
     CDS             8108..9499
                     /locus_tag="MIV85_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2962247.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9606..10646
                     /locus_tag="MIV85_002921"
     CDS             9606..10646
                     /locus_tag="MIV85_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBY2962248.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11135..11788
                     /locus_tag="MIV85_002922"
     CDS             11135..11788
                     /locus_tag="MIV85_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBY2962249.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVNASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11864..12073
                     /locus_tag="MIV85_002923"
     CDS             11864..12073
                     /locus_tag="MIV85_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962250.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12213..12779)
                     /locus_tag="MIV85_002924"
     CDS             complement(12213..12779)
                     /locus_tag="MIV85_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBY2962251.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            12940..13593
                     /locus_tag="MIV85_002925"
     CDS             12940..13593
                     /locus_tag="MIV85_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBY2962252.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13751..13927)
                     /locus_tag="MIV85_002926"
     CDS             complement(13751..13927)
                     /locus_tag="MIV85_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962253.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
     gene            14455..15399
                     /locus_tag="MIV85_002927"
     CDS             14455..15399
                     /locus_tag="MIV85_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBY2962254.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            15421..16047
                     /locus_tag="MIV85_002928"
     CDS             15421..16047
                     /locus_tag="MIV85_002928"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBY2962255.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            16081..17130
                     /gene="hisC"
                     /locus_tag="MIV85_002929"
     CDS             16081..17130
                     /gene="hisC"
                     /locus_tag="MIV85_002929"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBY2962256.1"
                     /translation="MREKESIRELKGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYK
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            17133..17711
                     /gene="hisB"
                     /locus_tag="MIV85_002930"
     CDS             17133..17711
                     /gene="hisB"
                     /locus_tag="MIV85_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBY2962257.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            17713..18318
                     /gene="hisH"
                     /locus_tag="MIV85_002931"
     CDS             17713..18318
                     /gene="hisH"
                     /locus_tag="MIV85_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBY2962258.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            18315..19037
                     /gene="hisA"
                     /locus_tag="MIV85_002932"
     CDS             18315..19037
                     /gene="hisA"
                     /locus_tag="MIV85_002932"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBY2962259.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            19019..19777
                     /gene="hisF"
                     /locus_tag="MIV85_002933"
     CDS             19019..19777
                     /gene="hisF"
                     /locus_tag="MIV85_002933"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBY2962260.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            19805..20473
                     /locus_tag="MIV85_002934"
     CDS             19805..20473
                     /locus_tag="MIV85_002934"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBY2962261.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         8167 a         1940 c         3629 g         6828 t
ORIGIN      
        1 atttattaaa taaataattg aataaaaaaa ttttattatg tatttataaa atttttgtta
       61 caaatttggc ataatatagt atactttaag tgtgtattag gttaaatcta taacaaatta
      121 gacgtatgat atagacttag tgtttattgg catttacaag aaatttgtta atatcaacta
      181 tttgtagttt gggcagttat aattattata ggggggatgt ccaatacaaa acaatcaacc
      241 aagaactaat attatattat aaagagttat agttttgtgt gtttatgttt ttaattaaat
      301 ttaaagtggg aaaaatatat ttgttagaat ggagaatagc gagatgagta ataaaatagt
      361 tagtaagaga caattaacag atagtattta tttaatggaa atagaggcac ctagagttgc
      421 aaaatcttct caaccaggtc aatttataat aattaaaaat gatgaaaaag gagagaggat
      481 tcctcttaca atagctgact atgatagaga aaaaggaaca gtaactattg tattccaaac
      541 agttggtgct tcaactaaaa agttagcaat gtttgaagaa aacgattttg taatggattt
      601 tgtagggcca ttaggacaag caagtgaatt tatacatgaa gatatagaag aattaagaaa
      661 taaaaagata ttatttgtag ctggtggagt tggttctgct ccagtttatc cacaagttaa
      721 atggtttaaa gagcatggat tagatgtaga tgtaataatt ggtgcaagaa ctaaagaatt
      781 aattatatta gaagatgata tgaaaaaagt agctaaaaat gtatatgtat caacagatga
      841 tggtacatat ggatttaatg gaagagttac agacctatta aaagatttag ttgataatca
      901 aggtaaaaaa tacgaccaag caatagtaat tggaccaatg ataatgatga aatttatgtg
      961 ccaattaact aaagaactaa atatacctac tatagtaagt ttaaatacaa taatgataga
     1021 tggaacaggt atgtgtggtg gttgtagagt tagtgttgga aatgaaacta agtttgcatg
     1081 tgtagatggt cctgaatttg atggtcattt agttgatttt gatcaagcaa tgagaagaca
     1141 gtctatgtac aagactcaag agggaagagc tatgctaaaa cttgaagaag gcgatagtca
     1201 tcatcatagt aattgtggat gtggaggtaa caaataatgg atgctaaaaa agtaaaagta
     1261 ccagttagag aacaagaacc tgctgtgaga gcaacaaatt ttgatgaagt atgcttaggg
     1321 tataataaag aagaagctat ggcagaagct aatagatgtt tggcttgtaa aaaaccaaaa
     1381 tgtgtgggtg gatgtccagt aggaatcgac ataccagggt ttataacaaa aattaaagaa
     1441 gatgatatag aaggtgctgc taaagtaata gctaagagca gttcattacc agctgtttgt
     1501 ggtagagtat gcccacaaga aagtcaatgt gaaggtgtat gtatacttgg aataaaatca
     1561 gatgctgtat caataggtaa attagaaaga tttgtagcag attggtcaaa agaaaatgac
     1621 ataaatttat ctgatacaga gcctaagaaa aatcaaaaag tagcagtaat aggaagtggt
     1681 ccagcaggtc tagcttgtgc tggtgattta gctaaaaaag gctatgatgt aacaatcttt
     1741 gaagcaatgc atgagccagg tggagtttta acttacggaa tacctgagtt tagacttcca
     1801 aaacaagctg ttgttcaacc tgaaatagac aatataagaa aattaggtgt aaaaatagaa
     1861 actaatgtaa ttgttggtaa aacaattaca gtagatgaac ttatagaaga tgaaggattt
     1921 gaagctatat tcataggttc aggagctggt cttccaatgt ttatgaatat accaggggaa
     1981 aatgcaaatg gagtattttc tgcaaatgag tttttaacta gagtaaactt aatgaaggct
     2041 tatagagatg attatgatac acctattagt tctggtaaaa aagttgctgt agtaggtggt
     2101 ggaaatgttg ctatggacgc tgctagaact gcattaagat taggttcaga atcatatata
     2161 gtttatagaa gaagtgaaaa agagcttcca gcaagagctg aagaagttca tcatgcaaaa
     2221 gaagaaggca ttatatttaa tacattaaca aatcctaagg aaattttagt agatgaaaat
     2281 ggatatgtta aaggtatggt ttgtataaga atggaattag gagagccaga tgattctgga
     2341 agaagaagac ctatagaaat agaaggttct gaatttgtac ttgatgtaga cacagttata
     2401 atgtcacttg gaacaagccc aaatccacta atatcttcta caacaaagag tcttgatata
     2461 aataagaaga gatgcttaat aacagatgaa aatggtcaga cttctaaaga gggtgtattt
     2521 gcaggtggag atgctgttac tggagcagca acagtaatat ctgcaatggg tgctggtaaa
     2581 acagcagcag catcaataga tgaatattta aaagcaaaag ttaatgctta atttgtaaat
     2641 taaagagagg gtgtctcaaa atgaactttt tagttcatga ggcactcttt ttgtacaaaa
     2701 tcaaatatgt tttaatcatt tcaacaatga aaatttcatt cctgtagaaa gtctaacttt
     2761 taggtcttag tacaatctct attttgatgt agccactttt ttagatggtt taataattta
     2821 tcagttatta ttgtaatatt tgatactaag taacataact ttgtctaact atgataaaat
     2881 agttatacaa taaaggtctt gtaaggagtg aataatgtgt ggctaataaa atcagatttg
     2941 tcaaatctaa cattaaataa tagaaaaata aattgtgtaa ttaatggtat tttaatatga
     3001 aaaaaagaga aaaagtattt gatgggctag tttttaagca tatattaatc ttattaatac
     3061 tattagtttt gattgattta acaagtacca tcatatatgc aagtaactct atggaaatta
     3121 cttctagaaa tatgattgag gcatcaaaaa gagaacttga aaactattta gaagtaaaca
     3181 tatctttatt aaaagctctt agtcaagatg atagattttc taatggtgaa acatcactaa
     3241 ttgaaaaggg aaaattatta agtccatatc aaaaggaata taatcttttt atgattggta
     3301 taacagatac aaaaggaaat gcttcaagta catataggga aaatgttaac tcaataaaag
     3361 ataagcctag ttttgagaaa gcaattaaaa caaagcaagt agtagtttca gatattgaag
     3421 tcagtaatgt aacaggtgac aaagtattta tcatatatgt accaattgta aaaaataatg
     3481 agatgattgg gaccattttt gcttcttttt attttcaaga tgtaaataat ttaataagta
     3541 gaagcaattt tgatgattct attaaatttc taatgataga taaagattat actattattt
     3601 ctcatccaaa caaaaaatat gtaaatgata aaagtaagat gcttgattta gaagggaata
     3661 ttataggaac cactaaaagt gaaatcttaa aaaatataaa taaaaaatgt caaggtgatt
     3721 ttttatcttg ggataattgg agattatata atgtaaaata tacgaacata aagtggacta
     3781 attggacttt agtatcaaaa tgtaatatat ttaagaactt taaaaatcta atagttaatt
     3841 ttatgataaa gttgtatttt tatatagtaa tatttatgat attgtggaaa ttaagtaatg
     3901 ctaaattaat agaacaactt aaaaaattgg cttattatga ttctttaagt ggaataaaaa
     3961 ataaagaaaa gtttagaaaa gattctatgt atattttaaa gaattattat caagataatt
     4021 tttacttagt acaattggat gtcaataaat ttaaatatat aaatgagatg tttggatatg
     4081 ctgaagggaa taagatatta attcatatat cacaggtttt aaataataat acaaataaat
     4141 atgaaatttg tgctaggatg gataatgacc attttatatt gttgattgct tgtaacactg
     4201 aagatgaact tttaaataga ttatctaaaa taaataaaga aatttgtaac ttaaatacta
     4261 ctaactcatc taagtataaa attgttatgt caagtggaat atataagatt actaaaaagg
     4321 atgatattaa aaagattgac ttgttaattg atagagcaaa tattgcagca aaaagtaaaa
     4381 aggaaaaata tgaacattca tattcatttt ttaatgaaga tacaagaaat cgattgtaca
     4441 aggaaaaacg attggaagat aatatgaata aagctttaga aaaaggtgaa tttatagtat
     4501 attatcaacc taagtatagt ttagatgatg taaatgaaat tgaaggagca gaagccttga
     4561 taagatggaa tagtccagaa tttgggttta tttcacctat agattttgta cctttatttg
     4621 aaaagaatgg ttttattgta aatattgata tgttcgtgtt tgaagaagta tgcaaaacat
     4681 taaacaagtg gataaataaa gggtatactc ctgtaccaat ctctgtaaat atgtctagag
     4741 ttcatttata tagggataat tttatagaaa atataactga tttgataagt aaatacaata
     4801 tatctcctga gtttattgag cttgaactaa cagaaagtgt tgtgtttgat aatttaaata
     4861 tattgattga tataatgaaa aagattaaag agataggatt ccttatatca atggatgatt
     4921 ttggttcggg atattcatct ttaaatctgt taaaagacct ttcttttgat attttaaaat
     4981 tagatagagg atttttaatc gaaacaacag atacaaaacg tggaaaaatt attatttcta
     5041 agattgtgga aatggcaaaa gcgattgata ttaaagtaat ctgtgagggc gtagaaactt
     5101 atgaacaagt agagttcttg aaagagatag gttgtgataa ggttcaagga tacttatttg
     5161 ctaaacctat ggtattagat gaatttgaaa aacacttaaa ctttaaattt gattaatcat
     5221 taataattat tagactataa gataccctaa caacttactt acaaatatgt aagttaattg
     5281 ttagggtatt tttatggtta aagtagtata ttcacgatat tatggtattg tagtaaaaat
     5341 aaaaaattat ggagaatata aaatgaacat attgagtatt agaaatatat caaaaacata
     5401 ttgtggaaat attccattta aagcattaga taaggttagt ctaaatatag aaaagggaga
     5461 atttgtgtct gttatgggac catctggaag tggtaaatct actcttttaa atataatatc
     5521 tacagttgat agacagagtg aaggtgaggt tgtattagat ggatatgatg taagtaaatt
     5581 gaaaggagaa aaacttgctg aatttagaag gaaacaactt ggttttgtat ttcaggattt
     5641 taatttgatt gacactttaa ctgttggcga aaatattatg ttgccactta cactagaggg
     5701 ggcaagtatc aaagatatga atatacaaac taaaagtata tctaaatttt taggaataga
     5761 taaaatttta gatagaaaaa cctatgaaat ttcaggaggt caagctcaaa ggtgtgctat
     5821 tgctagagct attataaata aacctgccat acttcttgca gatgagccaa ctggaaatct
     5881 tgattcaaaa tctactgatg atgttttgaa attatttact aggataaaca aagaacaaaa
     5941 ggtaacaaca cttatggtaa ctcatgaagc atatagtgca agttattcag atagagtaat
     6001 ttttataaaa gatggttgta tatatacaga aataaaaaaa tctgaaagca gtaattcttt
     6061 ctattctgat atactagctg ttttgtctca aataggaggt gtaagatagt ggattttaga
     6121 aagtttgctt ataataatat agttagaaat ttcagggcat atttagcata ttttttaagt
     6181 tctgtttttt ctataatgat attttttgtt tttgcagtgt ctatgttcca tccaattata
     6241 acaaaatctg gaatgcagag tggttctact gcatttatgg ctcttatgac ttcagaatta
     6301 ataatattcg gttttagtct actttttata ttgtactctt taggaaattt cttaaaatat
     6361 agattgaaag attttggagt attgatgata attggaatga gtaacagaca actgaaaaaa
     6421 ttgatattaa ttgaaaattt gataatagga tttttagcag tgatgttagg aatattactt
     6481 ggtttatcaa tttcaaaatt gtttttattg tatttaagca aactgtttta tatgaattta
     6541 actgaatttt attttccagt aaaagcaatg ctattgacta ttgtatcatt tatgatttta
     6601 tttttgataa caggaccaat gagcttaaaa ttattgagta aaaagagcat tttagagctt
     6661 ttagtaggta caaaaaagcc taaaaaagag ataaaatctt caaagctatt tggaataatt
     6721 ggtgtaatat gtcttatatt aggatatgct atgatactat ttggcaataa gttaaaaata
     6781 aatggaggta tgtatacaac agcactatta attactttgg ggatattttt atttttttct
     6841 caatttacta ttttgatatt aaagtattta aaaaataaag aaaaatttta taagaacaaa
     6901 gtaaatatgt tacttataag taatttgata tataaattaa aggataatac acgattgtta
     6961 tttttaataa caatactttt atcggctact ttagtagcat ttacaacaac ttcaacactt
     7021 gtaagttctc aaggagaagc ttctaaaaat aatttcccaa tggtttactc atatttttca
     7081 gagcataata atgaaaaaga atatgaagaa ctacaacaaa ttagagaagc aatcaaagga
     7141 tatgattata aggagttaag ttttcctgta cttaaatata atagggaagt cttactaagt
     7201 gtaaagaatt ataacaaatt atcaaaggaa ttgggattag ataaaattag ttcaaagtta
     7261 gaaaaatatg aagggattat aattcctagt agcaattcgc aagaacatat aaattcttta
     7321 aaacaattaa aaaattatag tataaaaaat ttaaatatag aagtaaaaaa atcaaaaaat
     7381 aaaataattt ttcctacagg actgtttagt aaagttgtgg ttataagtga tgacttatac
     7441 aatgaagtaa aaggtgaatt ttcaaaaatt aattttcatg gatttgatta taaaaactgg
     7501 caaagcagtg caaagataac tgaaaattta aaagaaaaac attttaattt ggatagagaa
     7561 tataacaggt catatttttt aacattacca gatatgtatt tagtagagtt acaacaaagt
     7621 aaaattcttc aatttatggg tgtttttata ggagtgatat tatttatagc agtttttagt
     7681 tttttatact tcagattata tacagacgag atagaagata atgtaaagta caaaaaacta
     7741 tcaaaaatag gtctatcttt taaaaatatg aataagattg ttagtataga gataggtaca
     7801 ttgtttttta taccgtattt tatagcaatt ataaatagca taatttcttt actgttttta
     7861 aatcaagtat taaataatag ttttaagtta gaaaatttgg gtatattact actgatatca
     7921 tctatatatt cactttattt ttacttatta aaaaaaaatt atactagaaa agtttggttt
     7981 tttgattaaa gtggtatata atagatatat aaattaatat ttaaaaagta gttaatatta
     8041 ggggagggca tttgcacctc ccttgtaata tgtggaaaat tgaatattag aagaaggagg
     8101 agacttgatg gaaaatcaac aattattagg aacagaacga attagtaaat tactactaaa
     8161 atattctata ccagctataa taggtatgtt ggtaaatagt ttatataatg tagtagatag
     8221 aatttttatt ggaaatatac caggggttgg accacttgca ataacaggtc ttggtgtaac
     8281 aatgccaata atgacaataa tacttgcatt tgggatgttg ataggtatag gaactactac
     8341 taccatatca ataaaacttg ggcaaggtaa agtagaagag gcaagaaaac ttataggaaa
     8401 tgcaatgacg ttatctgtaa taacaggaat tatcataatg atacttggaa tattatttgc
     8461 aaataaaata cttacattgt ttggagcaag tgaaaatact ttaatatatg caaaatcata
     8521 tatcaatatt atattattag gtacagtagt aaatcttctt tccttttctt taaaccactc
     8581 aataagagct gatggtagtc ctaaaatttc agcaggaata atgatagtag gatgtttaac
     8641 taatatagtt ttagactgga tattaatatt tggattcaat ttgggaatac aaggagctgc
     8701 aattgctaca gtaacttctc aggctcttac agctatttta actatagggt attatataag
     8761 tggaaaatca aacttacgat tcagtaaatc taatctaaaa ttagataaaa agctaataaa
     8821 agcagtgttt gcaataggta tgtcgccatt tgctatgcaa cttgcagcaa gtttagttca
     8881 agtaatatca aatattgcac ttaaaactca tggtggagat ttagctatag gggctatggc
     8941 tactatttct tctattgcaa tggtattttt gatgcctatc tttggaataa atcaaggagc
     9001 gcaacctatt ataggtttca attatggagc tgaaaaatat gatagggtta aaaaagcata
     9061 tttaggttca ttagtagtag ctactataat tttatgtatg ggtatggtag tagttatgct
     9121 tttcccagaa gctattatag gtatatttaa taaagaccct gaacttatga atatatctgt
     9181 taatggatta agaatatact tacttatgtt gccaattgta ggcttatcag ttacaggaac
     9241 aaactttata caatctatag gaaaagcaaa aatggctatg ttattgagcc ttttaagaca
     9301 agtaatttta ttgataccag cagtattaat tcttcctaca ttcttaggtt tacagggtgt
     9361 atggacagct caaccagtgt ctgattttat agctacagta attacaggta tagttgtatt
     9421 tagagaatta aaaagatata ctcctaaaac tgaaaaatta aatgaaaatg aaagactaaa
     9481 cgagataact actgagtaaa aatataaatt cagataattg agcaagaaat tgcaaaaaat
     9541 acgattatat gataaaataa aaccgctgtc aaggataaga gaaattctaa ttatggagtg
     9601 attttatgga atttacaaag aaaagcaaat taaaaaatat gtatgtaaac atgaatgtag
     9661 ctagaatgtt gtctaagata aatgagtata agggtagaca actgctttac aaaaaacaac
     9721 caaaagaaat tttagaaaac ttagaaaaaa aatctttagt agattgttct gaatctacat
     9781 acattggaaa tcaaagagat agtagtaatt ttaatctaga aaagttgata agtaatgaag
     9841 ttacacctag aagtagagag gaattgagta ttgttgaata cagagatgtg gtaaaaacta
     9901 ttaacagtgc ttatgagagt attcccatca gttcacaaac aattcttgag cttcatggat
     9961 acttatataa attttcatct actagaggag gaagttataa gtcagataat gattttattg
    10021 aacacaattt aaaacctagc gaatttataa gtactgattc aagtgtcaat aaagttgaaa
    10081 aagctgtaga agaaatatgt gaagcttata atacattgat agaggaagat gaaattgata
    10141 tattaatatt aatttctgca tttgtgttag atttcatatt gatacatcca ttcaaagaag
    10201 gtaatataaa aatggcgaga gtacttatcc tattgttact aaataaaaat gggtatgaag
    10261 ttggaagata tataagttta ggaaagatat ttgatgatag ttcatatgaa tattatagta
    10321 atttaaatta tttgaaagcc tcaataggta gtgaaaaagc agatatgaat gcatggattg
    10381 agtatttttt agagacgata ttaactgcat atgagaagct ggatgatagt ttaaatatat
    10441 ctgataagaa aagacaaaca aaaactagta gaatagagaa aataataaat tctacccttg
    10501 gatattttac aaaagaagat ataagagatt tatgtcctga cattccagaa cctactataa
    10561 atagagtttt taataatcta agaaaacaag ataagataga agttgttgca agaggaagaa
    10621 gtgcaaaatg gaagaaaaaa tattaaaaaa tgtttagata actaaaatgg tatagtgttt
    10681 tacactatac catttttaat gtcattagca tgagcaataa tttaacaact taagcaatat
    10741 caattttatt tattgattat ttttgaactg aaaaatggcg ttatatggta tacctcagtg
    10801 gtaattaatt ttggatgaga agatataata ttacagaata tattaggagt atatgtagaa
    10861 aaaatataat aaaagtgtga ggcttagtaa ttaacaaatt atgtggcttc acactttttt
    10921 ataaaataaa gatacttagc agaataatat tttagttgat atgtttataa gatggtactt
    10981 gtttgggtaa aagtataaat agtaaaaaag tagaagtaat gtgtataaaa acataagtta
    11041 cattctgtaa taatagttat tttataattc aacaaaagaa tagaatgggt atatttgtga
    11101 aataataata taaaataatc ttaggagtga gcttatgaag aaaaaattat tatatataaa
    11161 tgtaaattca aaacctgaag acttatcttc aagtaaaact gtagcaagaa aatttataaa
    11221 taaatttatg gaaaaaaata aagattttga ggttgaagag atagaccttt ataaagaaca
    11281 tataccaaga cttgagtatc agtactttga aaaaagaaat agcatagtta gtgaagaaaa
    11341 tgctaaaaat ttagacgata aggatagaaa agagcttaca aagattagaa atctttgtga
    11401 ccaatttgtg aatgcaagtg tttatgtaat agcagcacct atgtggagtt tatcttttcc
    11461 agcaccactt aaagagtata tagattgtat aattcaagat ggaaaaacta tatcttttga
    11521 aggcaatgat aaaccacaag gaattttaaa tgatattgat agaagtatgg tatatataca
    11581 atcttctggt ggacacatac catgggtgtt gaagccagtt atgaataaag ggttaaatta
    11641 tgtggaaagt attatgaaat ttataggaat taaaaaattt gatgaattgt tagtagatgg
    11701 aactggaact agtgaagaag aaagacaagc tgcaatagaa aaagcatctg aaaaaataga
    11761 tggtataata gatgggatga aattttaatt ataatatttt attaaaaata taaaggaaaa
    11821 acctctttta atgtagaaac ttatattgaa ggaggcgaga atcatgcgag aagaaaaaag
    11881 taatgaaaag tatgattgtt attggtgtaa tcaagagaat aatttctgtg tagaaataaa
    11941 agataatata gtcatgatag atgatggcac tggtacgtta aaacaagccg ttttcatagg
    12001 gtataaacaa atccaaatta atttaaactg ttcacattgt caaaacttaa atagaataaa
    12061 attaaatttg tagaatttta aaatggaaat tattgaagga attaaaaata gaaagtgtta
    12121 atatttagac tgaaaattat attttataca ataaaagttt atttaaataa cattgtattt
    12181 taatatttat tttcagtctt actttattaa aattattttt tggttatgtc tggaaaatat
    12241 ctgtctacta atttttctga aatatttttt aattggtcag ccattgaagt cagacttaat
    12301 aaggctatca ataaatcatc tttattttct ggatttatac taatattttc aaaattagac
    12361 tctataaagt ccggtatatt ctttctttga ttttctttta ttaacatgaa tttttcgtaa
    12421 catgaaacta aatctttttc actgaaatta tccttttcat acacaccatg taagattctt
    12481 ttaatttctt gtattgtaag tgtatttttc atagaataaa taattatcat ctgtaaaatt
    12541 tgttctttag tatacttttt tcccttaact ggtttgatta atccctcttt gctgtaatta
    12601 tttatcatgg ttttagtaag aattttatca ctttcaaatc ttttattagc agaaagctta
    12661 ttgtcaatta gagaaataat ttgatccata tataagtcaa tagatggaat atcgtttgaa
    12721 gttatatctg cattatttag tgtttctagt attatagtat taagttcatt attcatcata
    12781 tgttacctcc ataatatata taatacacta aattagaaag taaaacaata ttaaggcttg
    12841 taaaaaaaac ataaagtggt ataattaaat atataatata gtaatcaaaa ctatatttat
    12901 gaatctgatt tttaaaatac ataattgtag gaggacgaaa tgtatcaatt ttttttaaag
    12961 ggtagagacc caataagcag tttaactcat tttataggtg cttgtttatc tcttttagca
    13021 actataattt tagtttttca atctgttaca ttacaggaaa cttctctctt gatgatagta
    13081 tctgtatctg tatttggact ttcactaatt gctttatata gtgcaagttc gtattatcat
    13141 tttttaaagg ggacaccaga acaagaattg ttttttagaa aagtagacca tgcaatgatt
    13201 tacgtattga ttgctggctc ttatacacca atatgtctga attttatgga aaaaaaagaa
    13261 ggcataatat ttgttacagc aatatggata gttgcattta ttggcataat aataaaaata
    13321 ttttggatgg atgcacctag atggttatct accagtatat atttacttat ggggtgggca
    13381 attgtttttg atataaatgc attcaattca attcctaagg attgccttag actattaatt
    13441 atggaaggtg tatcttactc tataggtgcg attatttata taattaaaaa gcctaatata
    13501 agtcctgagt ttggatttca tgaaatattt catattttta ttatgatagg ttctttattt
    13561 cactttttag cagttttatt gtatgtttta tagttttaaa agatttgatt aattgatact
    13621 aaaattctac aatgaataaa atggaactgc cttatataga ttatatctta gacaataaga
    13681 cagttcctta ttataaatat taaattctac ttataataaa attttgataa aaatagtcca
    13741 ttcaaaatgc ctattccata attcctttaa tgtacttttc atttacgaca tatagtttga
    13801 atttatgtac tataattata tcctctaaat tctctgaaac actaacaatt ctgacacatt
    13861 tgtttctaat ttctacaggt aaatctaaat catttgttaa attcacatag tcatcatatt
    13921 tatacataaa atcatccctt tacattaaga tatacttatt atactatatt ttaataagtt
    13981 tttttaaatt attacaattt ttcccgaaat ttcatttttt atacataaaa tttccaaatt
    14041 aggtaaagat taaatttttt attgtataaa caaaagttac atataaaata ttttattcaa
    14101 ttttttaaat aactattgcc aatttttgaa aaatatatta ttattaatag taacaaaaaa
    14161 ctgtaaattt agaatattaa taaaaattat ttgggaggaa attatcatgg tgagattaaa
    14221 tatagtaaaa ttaaatacaa aattaaatca tcaccatcat catagattaa agggattgta
    14281 atatgaaatt aattcataga cacaagccct gtttttagtg taattggtct tgtatctatg
    14341 atgggaagta attttaagag aaaattatag ccatataggt ataaagccta tgtggctttt
    14401 ttattgtttt aaatttgcaa atataagagt aaatttaatg aagagggtga gaatgtgaaa
    14461 tttttgagga ttgaagatga ggttatttat tctaaaaaaa gatataaatt aaaaagggaa
    14521 atagataaac tttttttgga tgaagaatat tttcaaatag aaccacaatt atttgaagaa
    14581 tatgatgaat ttacaactat aaataataaa attccagaag aatctatggt aaaggttgta
    14641 aatggaaaag taatggtact tagagctgat ataactacaa gtataataaa aagccttgta
    14701 ccaagatggg aagatggttt aaagcttaag cttttttata attcatcaat atataaaaat
    14761 aaaaatacag ttggaataaa agagataaga caaataggtt gtgagtatct aggagaagcc
    14821 tctgtagaag cagatagaga agtagtgaaa ttagctctta agatacttga aaaatacaat
    14881 aataatttta ttctagaggt tgggagtagc aagtatattc atggtttgtt agaagaatta
    14941 aatttaaata agaattgtga aaatcaaatt aaaaatttac tatatacgaa gaacactcat
    15001 gaactaaaag tatatattga agaattaaaa attaagcgtg aagtaaaaga gttattatca
    15061 aatattttaa gtttacaagg gaatttatat aatgttattg aaaaatcaaa caagttctat
    15121 tgtaataata agatgaagca agctcttgaa gaattaaagc aagtaaataa cttgattgag
    15181 gaatgtaatt ttttagataa ggctagattt gatttatcaa tgattactat gcttgactat
    15241 tatgaaggaa ttatgtttag aggatactac ccaaactcat ataaagaaat tcttagtggt
    15301 ggaagatatg attctttaac taaagagtat ggaaaagaaa ttccagccat tggatttaca
    15361 ctaagtgttg atgagttaat gaagtatgta tataagtaaa gtttagaagg agggattgct
    15421 ttggattatt tgactatagc actagcaaaa ggacgaattg aaggggaatc atttaaaaaa
    15481 tttaaaaaaa tgggtctagg agacagtata gacacagata cgagaaaact aatttttaaa
    15541 gatgaagaaa ataaaattat atatatacat gtaaagccat cagatgtagt tacatatgtt
    15601 gaaaaaggag tcgctgacct cggtatagca ggtaaagata ctattttaga gaatgagaca
    15661 gatgtatatg aaatatatga tttaggtttt ggaaaatgta aatttgctgt agcaggatta
    15721 aagggagata gcatatatag agaagatgaa tatttaaaag tggcaacaaa gtatcccaat
    15781 atagcaaaaa agtattttaa agagaaaggt caaaaaattg aaataataaa attaaatggt
    15841 tctgtagaac tagctccaat agtagggttg tcagatgtaa ttgtagatat agttgagact
    15901 ggcaatacac ttaaagcaaa tggtcttgaa atattagaag acatatgtaa tataagtgct
    15961 agaattatat caaatagagc tagctataga tttaaatatg aacaaattca gaatataatt
    16021 cgtttatttg aagaacttga taattaaaat ataattgagc tttataagga gggatttaag
    16081 ttgagagaaa aagaaagcat aagagagtta aagggatatg aaccaaatca cgtaaactgt
    16141 aaagtaaaac ttgatgcaaa tgaaggaagt aagaggttgt ttaaatacct tattaaagaa
    16201 atttcagata gtgatataga tttaaattta tatcctgaag attcttatag tgatttgaaa
    16261 gaatctataa tagattacat aaatatttct ggagtaaata agaaaaatct tctagtagga
    16321 aacggttcaa gtgaaataat tgatttaata atacatactt ttgtagataa agatgaagta
    16381 atattgagtt tctctccaag ttttagtatg tattctatat atagtcagat aaatgggtct
    16441 aaatttatag gtgttgaaag tgatgaaaat ttagttataa atatagataa tgtgattgaa
    16501 aaagtaaagg agaataatcc taaaatagta attgtatgta atcctaataa tccaactgga
    16561 acaatattaa agagggaaga gataataaag cttttagatt caactaatag tctagtggtt
    16621 ttagatgaag catatatgga ttttggagaa gaaagcatgt taagtgatgt ttttaagtat
    16681 gataatctaa tagttcttag aactttatca aaggcatttg gattggctgg aataagaaca
    16741 ggatatatgt tatctaatag tagtttaata aattctgttg agaaagtaag acctccatat
    16801 aatttaaatt cattatcaga ctttattgct acaagagcac ttagaaataa agatgtggta
    16861 aaggcttata taaaggaagt aaaagaggaa agagaagttt tatataaaga aatgattggt
    16921 atgggaatta aagcatataa atcacaagca aattttatat tattttattc tgaaatcgaa
    16981 aatttatcac aaaaacttat tgatagaggt gttttaataa gaaaatttgg tggaaagtta
    17041 gaaaattatt acagagttac aattggtgat aaagaagaaa attctatgtt tgttggagct
    17101 ataagagata ttttgaaaaa ggagaaatag gtatgagaat ttggaaggta gaaagaaata
    17161 ctcttgaaac acagatttta gtagaattaa atattgatgg ttctggtaaa gctgaaatag
    17221 atactggaat aggattttta gaccatatgc ttaccttaat gtcatttcat ggcaagttcg
    17281 atttaaaagt gatttgtaag ggtgatacat atgtagatga ccaccatagt gtagaagata
    17341 taggtatagc tataggtgaa gcatttaaaa atgctctagg tgacaaaaaa ggaatacgaa
    17401 gatattctaa tatctatata cctatggatg aatctctatc aatggtagca atagatataa
    17461 gcaatagacc ttatcttgta tttaatgcta aatttgatac ccaaatgatt ggtagtatga
    17521 gtactcaatg ctttaaagaa ttttttagag cttttgtaaa tgaatcgaga gtaacattac
    17581 atatcaatct cttatatggg gaaaatgacc atcataagat agaaagtatt tttaaagcat
    17641 ttgcaagagc tttaaaagag ggtagtgaaa tagtttctaa tgagatagca tcttcaaagg
    17701 gggttttgta gaatgaatat aatagtagac tatggtcttg gaaatataga ttctgtgtct
    17761 aggggtttta gaaaagctgg aatagaaact aaaatttcta gtgatataga tgaaataaaa
    17821 caggcagatt cacttatact tccaggtgtt ggagctttta gagattctat aagtgcctta
    17881 gataaactag gattgatacc aataataaag gagcatgttt ctaagggtaa atttatgata
    17941 ggtatatgtc taggaatgca attactttat gaaaaaagtt atgagtatgg agaatatgaa
    18001 ggattaggac ttataaaagg aagtattgat aaactggata taagtttaaa agtgccacat
    18061 atgggatgga ataatctaaa atttaataag gcaaatgatg atatacttaa atatataaat
    18121 gaagatgatt atgtatactt cgttcactca tattatgcaa attcatcaaa tgaagaacta
    18181 attgcatttt cagaatatga aaagaaaatc cctgctattg ttagaaaagg caatgtatat
    18241 ggtatacaat ttcatcctga aaaaagtgga gaagtagggt taaatatatt aagagcatat
    18301 ggggagatga taaaatgata atatttccag caatagatat aaaagataat aagtgtgtaa
    18361 gacttacaca aggagaattt gacaaagtaa atgtatatta tgataatcca ttagaagtag
    18421 catataaatg gaaaaatgaa ggagcagaat atatacatat agtagattta aatggtgcta
    18481 gaagtgaatt tggtgtaaat acaaaaataa ttgaggacat agcaaacaat atagatatac
    18541 ctattcaagt tggcggtgga gttagggata aggaaaaagt caaaagttta ataaatgctg
    18601 gtgttactag agtaatatta ggtagtatag cgattgaaaa tttgaattta gttgaagaat
    18661 tggtcaatga atataaagag aaaattgtag tttctataga tgctaaagat ggaaaagtag
    18721 cagttagggg atgggaagtt gtaagcaatg tagactcatt aacattatgc aaacaacttg
    18781 aaaagatagg tgtacaaact attgtttata cagatatatc aaaagatggg atgttgcaag
    18841 gtccaaattt tgacatatat gaaagaatag caaaggaaac atcactaaat gttattgctt
    18901 ctggaggcgt aacttctata gaagacgtaa aaagactaaa agctatgaac ttatatggtg
    18961 caataatagg taaagcgctt tatgataaaa agatagactt taaggaggca caacaattat
    19021 gcttactagg agaataatac cttgtctaga tgtgagaaat ggaagagtcg taaagggaaa
    19081 aaaatttaaa gatatagtag atgttgatag tccagaagta cttggaaaat tttatagtga
    19141 ttgtggtgca gatgaacttg tattctatga tataactgca tcaaatgaag agagaaagac
    19201 atctttagaa tttgtgacaa aagttgcaga aaatataaat ataccatttt gtgttggtgg
    19261 aggagtaaat aaattagaag atttcactga tattttaaga aaaggtgctg ataaagtttc
    19321 tataaattca tcagcagtca aaaatcctga attaataagg gaagcttcat taaaatttgg
    19381 agcacaatgt gttgttttat cgatagatgc aaagaaaaat gaagagggtt catggagcgt
    19441 atacgtaaaa ggtggaagag aaaaaactaa tctggatgca attgaatggg ctgttaaagg
    19501 tgtagaactt ggagcaggag aaatcgttgt aaatagtatg gatgaagatg gaatgaaaaa
    19561 tggatatgat atagaattat tatcaaagat aacttcttta gtaaatgtac ctgtcatagc
    19621 atctggaggc gctggaaaaa aggaagattt ttatgaggcg gttaataaat ccaatgtaga
    19681 tggaatttta gcagcatctg tttttcattt tggcgagata aaaataaacg atttaaagaa
    19741 atatttaaaa gacatgggtg tagaagtaag attataagtt aaatactaaa aggagattag
    19801 aaatatggat aataagtgta acaatgtata cagtgatgaa gtagagaaat ttataagaag
    19861 tataaagttt gatgataaag ggttagtccc tgttgttgtt caagaggtag ttagcaaaga
    19921 tgtactgatg ttagcatata tgaataaaga tgctataaag aaaaccttaa aagataaagt
    19981 agcttgctat tttagtagaa gtagacaaga actttgggtt aaaggtgaga catctggtaa
    20041 tactcaaaaa gtagttaaga tgtcttatga ttgtgatgta gatactatac tactttttgt
    20101 tgaacaaact ggtgtagctt gtcatacagg caattattct tgtttttaca gagacttgtt
    20161 tgatgatagt tcaaaaatgg agcttgaagt acaaacaaat atattgaaag aattatatga
    20221 tttaatcaat gaaagaaaaa ataatccagt tgaaggttct tatactaatt atctttttga
    20281 aaaaggaata gataagattc ttaaaaaagt aggtgaagag agtagtgagg taattatagc
    20341 atcaaaaaat accgataaaa gtgaacttat ttacgaaatt agcgatttag tatatcatac
    20401 attggtttta atgatagaaa aaggtgttga aattgatgaa ataaaaaaag aattacttaa
    20461 aagaagaaaa tagaataaga tagattaatg ggtaataaga aaatatacca cttttaataa
    20521 aaagtggtat attttttatt ttatattttg atttatagaa taat
//
LOCUS       DAGQVA010000073        20490 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.073, whole genome shotgun sequence.
ACCESSION   DAGQVA010000073 DAGQVA010000000
VERSION     DAGQVA010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20490
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.073"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            133..2151
                     /locus_tag="MIV85_002935"
     CDS             133..2151
                     /locus_tag="MIV85_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2962262.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            2659..4671
                     /locus_tag="MIV85_002936"
     CDS             2659..4671
                     /locus_tag="MIV85_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2962263.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKIYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            4913..6826
                     /locus_tag="MIV85_002937"
     CDS             4913..6826
                     /locus_tag="MIV85_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962264.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKVTTYISFVKKELVKYWPLIIEKCDGISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            6819..9038
                     /locus_tag="MIV85_002938"
     CDS             6819..9038
                     /locus_tag="MIV85_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBY2962265.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKSGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLSLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9147..9977
                     /locus_tag="MIV85_002939"
     CDS             9147..9977
                     /locus_tag="MIV85_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBY2962266.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            9967..13434
                     /gene="addB"
                     /locus_tag="MIV85_002940"
     CDS             9967..13434
                     /gene="addB"
                     /locus_tag="MIV85_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBY2962267.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIINFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13434..17261
                     /gene="addA"
                     /locus_tag="MIV85_002941"
     CDS             13434..17261
                     /gene="addA"
                     /locus_tag="MIV85_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBY2962268.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKSDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17307..18518
                     /locus_tag="MIV85_002942"
     CDS             17307..18518
                     /locus_tag="MIV85_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBY2962269.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18505..>20490
                     /locus_tag="MIV85_002943"
     CDS             18505..>20490
                     /locus_tag="MIV85_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBY2962270.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLL"
BASE COUNT         8829 a         2020 c         3588 g         6053 t
ORIGIN      
        1 ttttataatt tttttagaag tttatttttt atgtacttat ttataatttt gggtaaaaac
       61 actttgatat aatttcaaaa attaaaaggt taaaaaacaa agtagaaatt tatgttaaat
      121 aaggagatta atatgagaag aaatacaaaa ttattaacaa cagggattct ttcaatggca
      181 atcgtcgcac ctacaatggc atttgctact gaatctaatg ctatggaaaa taacgctgat
      241 ttaaatataa acttagagaa aaaaagtatc gttttaggta gtacctcaaa agtcagtgtt
      301 aagtttaaag aaaaaccaga tgcagatagc attacattaa agtataaatg ctatgatatg
      361 ccattggata caactttaaa ctacaatcaa tcaactgagt catatgaagg aactatcaat
      421 tataataaag acccagaata tctaaatgtt tgggaactac aagggataac aataaacagc
      481 aaaaataatc ctaaaacttt aaacaaacaa gaactagaaa agatgggatt aaatttaaaa
      541 gactataatg taacacagga atgtataatt gaagatataa cttctagaaa agatgtaaat
      601 aaatatttaa gaaaaacttc tgcacctatt acagaactta caggaagtga tagatacgaa
      661 acagcagtta aaataagtaa agaaggctgg aaaaatggtt cagataaggt agttataata
      721 aatggggatg taagtataga tggcattata tcaactccac tagcaactac atataatgcg
      781 ccaatacttt tggttgaaaa aaacaatgta cctaatagtg taaaatcaga attaaagcgt
      841 ttaaatccta gggatgtaat tataattgga gatgagaatg ctatttctaa aactactgct
      901 aatcaaatta aatcgactgt aaatgctagt caaacacgtc taaagggctc taatagatat
      961 gagacatctt tattgatagc aaaggaaata gataaaaatc atgatgtgga aaaagtgtac
     1021 ataacaaatg ctaatggcgg agaagtggat gcacttacta tagcagcaaa agcaggtcaa
     1081 gacaagcaac caattatatt aactgataaa aatagtatta cagacaacac atataaatgg
     1141 ttaaagagtg aggatttaca aaatgcttat tttataggtg gccctcaaat gatatcaaca
     1201 aatgttataa ataaggtaaa tgatataact aaagataatg ttactaataa tagagtatat
     1261 ggagcagata gacacgaaac aaatgcaaac gtaataaaaa aattctatac agatgatgag
     1321 ctagaggctg ttttagtagc taaatcagat gtacttgttg atgctttagc agcaggtcca
     1381 ttggctgcca acttaaaatc tccaatactt ataacaccaa agacgtatgt atctgcatac
     1441 cataaagaaa acttagaagc taaatcggct aataaggtat ataaaatagg aggaggattg
     1501 acttctaagg taatgaactc tatagcatca tcattatcta aacacaatac gactccaaca
     1561 gaaccaggaa atagtggggg taagacagtt atgattgacc caggacatgg tggttcggac
     1621 actggaacaa caggtaaacc attagggggt attaaagaaa aagactatac attaaatact
     1681 tcacttgcga caactgaata tttacgttca aagggattca atgtaataat gacaagagat
     1741 acagataaga ctttatctct tggaaataga actgctttat ctaactcttt gagaccagat
     1801 ttatttacga gtatacacta taatgcatct gatacaactg ggaatggtgt agaagtattt
     1861 tataagctta aagataaaga tggaggaact actaagactg tagctacaaa tatattaaat
     1921 agaatcttag agaaatttaa tctaaaaaat agaggtgcaa aaacaagaac actatcaact
     1981 gaccctacaa aagattattt atatgtttta agaaataatg atatgccagc tgtacttgta
     2041 gaatgtgcat ttttggataa tgagaaagat atgagtttac ttaatacatc aaataaagta
     2101 aaagaaatgg gtacacaaat aggtaaaggc atagaagatt cattaaaata gtctacaatg
     2161 agagcataga aaaatttaaa ataaattaat ctataatttt aaatttaaac taaagctata
     2221 agataagaat gtaattataa tagtaataaa gactgtatat acattgtgca tataaatgcg
     2281 aaatgaggta tatacagtct ttttataatt aattgtaaaa tgatttatgt tatatgaaaa
     2341 atttacatat attaaggcta cagttaattg tcaagagctg gagtattcat ttgtaataca
     2401 caatataagc ttaattacta tattttattg tgtgtttttt gtggattttt atgtcaataa
     2461 atgatatagt atagataatt aaatgtatta aatatattta atttttttat tttttgagtt
     2521 ttataagttt atttttatat attacttata tattacttat atattattta tattttgggt
     2581 tagatacact ttgacatatt ttcaaaagtt aaaagattaa aaataaagta gaaatttatg
     2641 ttaagtaagg agattaatat gagaagaaat acaaaattat taacaacagg gattctttca
     2701 atggcaatcg tcgcacctac aatggcattt gctactgaat ctaatgctat ggaaaataac
     2761 gctgatttaa atataaactt agagaaaaaa agtatcgttt taggtagcaa atcaaaagtt
     2821 agtgtcaaat ttaaagaaaa accagatgca gatagcatta cattaaagta taaatgctat
     2881 gacatgccat tggatacaac tctaaattac aatcaatcaa ctggggcata tgaaggaact
     2941 atcaattata accaagaccc agaatatcta aatgtttggg aactacaagg gataacaata
     3001 aacagcaaaa ataatcctaa aactttaaac agacaagacc tagaaaagct gggattaaat
     3061 ttaaaagact ataatgtaac acaggaatgt ataattgaag acataacttc tagaaaagat
     3121 gtaaataaat atttgagaaa aacttcttca cctattacag aacttacagg aagtgataga
     3181 tatgaaacag cagttaaaat aagtaaagag ggttggaaaa atggttcaga taaagtagtt
     3241 ataataaatg gggatgtaag tatagatggc attatatcaa ctccactggc aaccacatat
     3301 aatgctccaa tacttttggt tgaaaaaaac aatgtgccta atagtgtaaa atcagaatta
     3361 aagcgcctaa accctaaaga tataattata attggagatg agaatgctat ttctaaaact
     3421 actgctaatc aaattaaatc aactgtaaat gctagtcaaa cacgtttaaa tggttctaat
     3481 agatatgaga catctttatt gatagcaaag gaaatagata aaaatcatga tgtggaaaaa
     3541 atatacataa caaatgctaa tggcggagaa gtggatgcac ttactatagc agcaaaagca
     3601 ggtcaagaca agcaaccaat tatattaact gataaagata gtattacaga caatacatat
     3661 aaatggttaa agagtgagga tttacaaaat gcttatttta taggtggtcc tcaaatgata
     3721 tcaacaaatg ttataaataa ggtaaatgga ataactaagg atagtgttac taataataga
     3781 gtatacggag cagatagaca cgaaacaaat gcaaacgtaa taaaaaaatt ctatacagat
     3841 gatgagttag aggctgtttt agtagctaaa tcagatgtac ttgttgatgc tttagcagca
     3901 ggtccattgg ctgcgaactt aaaatctcca atacttataa caccaaagac gtatgtatct
     3961 gcataccata aagataattt agaagctaaa tcagctaata aagtatacaa aataggagga
     4021 ggattgactt ctaaggtaat gagctctata gcatcatcat tatctaaaca caatacgact
     4081 ccaacagaac caggaaatag tgggggcaag acagttatga ttgacccagg gcatggtggt
     4141 tcagcacctg gaaattcatc tggaggaatg attgaaaaag attacaattt aaatacttca
     4201 cttgcaacaa ctgaatattt acgttcaaag ggattcaatg taataatgac aagagacaca
     4261 gataagactt tatctcttgg aaatagaact gctctatcta attcattgaa accagattta
     4321 tttacaagta tacattataa tggctcaact aataaacaag gtcatggtgt agaagtattt
     4381 tataagctta aagataaaaa tggagggact actaaaactg tagctaccaa tatattaaat
     4441 agaattttag agaaatttaa acttacaaat agaggtataa aaacaagagt acttcctagt
     4501 gattctacaa aagattattt atacgtttta agaagtaatg atatgccagc tgtacttgta
     4561 gaatgtgcat ttttggataa tgaaaatgat atgagtttaa taaactcatc tgcaaaagta
     4621 aaagaaatgg gtacacaaat aggtaaagga atagaagatt cattaaaata aatggaaata
     4681 aaaatattta aaaacttaat gtaaatttat agttgtaaat ttatactaaa gtcaaaaaat
     4741 gaaatataag tgtatcaata gtaagactgt atgtacattt gcacatgtga atgcaagtat
     4801 atatacagtc tttttttgta gttaaatgca ataatttgat tgtgttttgt aaaatacaca
     4861 atatgatata attagataat atacacttaa tttaattgag gaaggtgatt atatggaata
     4921 tttatttgaa aaaagtagtt taaaagaata tggaaatgaa gctttagata aatatagaga
     4981 attattagat aaaactggta ataattcaag gtgtattctt ttgttagtac caaacaataa
     5041 cacaaagata cgatatgaaa gggctctaag attaaattat agtgaagaac tgaaagtaac
     5101 aacatatata agttttgtga agaaagaatt agttaaatac tggccactaa taatagaaaa
     5161 atgtgatgga ataagtacaa aggttgtatc tccaacattt atatcaaata gtttaagtga
     5221 atatttaata gtgcaaaaag ttaaggaaaa aaggatacaa gaaggatatt ttgaagatat
     5281 tacaggaacc aataaatcca tagcaaatag tataatgact aacataaata agtctgcatt
     5341 taatttaatt gattttgatt ttattggaga aaaaatatat tcatcaaaga aaaataaaga
     5401 tagtatatat agattttcat acactcaaat ggatgaaatt atatcatatt atataaattc
     5461 cttactatca aattcaattt tagataatgc attaagcata tatttataca atcaatacct
     5521 acttaatgat gatttttatt taaaaaactt atttacagaa gtgagatata taattgtgga
     5581 tagccttgaa agctcaagta atgcagaagt tgattttata acagaagcat tggataatac
     5641 attacaaagt tatatatatt ttgattatag tagggattat tctgtattta ataatgtgga
     5701 tatagactat ataaatgaga aaataatatc aaaaattaag cctaaagaag aaaatattaa
     5761 aaagaaggag attagaatag aagatttata cttattacct gcaaatatag aattaaatca
     5821 atcaagtcaa ttatataatg aaatgttaga tttaataagt gaaaaagtta tatctcttat
     5881 agaagaagat gtatctccaa gagatatagc aattatatct cctataaaca atagtatatt
     5941 ggagcatcaa attagagatt ctttgataga aaaaaatata gatgttttta gtactaagaa
     6001 ggataaaaaa gctgtggatt atccatatgg gaatgcattg gtagtggcta catgtatatt
     6061 ctatggatat ttagatttta taaaagatga tgaatactta agctttttag aaactctttt
     6121 agaaataaat aggataaaag catttaagat ttttaatgaa acaagacatt taagtattga
     6181 taatatagat gaacatagtc agtatcgtga tattttacag tatattgaag aaaaaaagaa
     6241 gagtgatata aaaatacatg aatttttaac tcaattttac atagataaaa tgttaaattt
     6301 aaaagaaggt aaaaagaatg ttgggttatg taaaaagata atagctgaaa gtgagtcttt
     6361 tagtgaaagt ttaagtctac ttgggatgaa aaaagaaaag atatttgtag aagctttaaa
     6421 aagtacaata aacgattatt actctgttgt cgatatagaa gagttgaaat ccaaagacaa
     6481 aatagtaata actactcctt attcatatat atcatcaaat atagatagaa gtatacaaat
     6541 atgggtagat ataggaagta atgcttggaa tatgaaaata gaaaaagata taagtaattt
     6601 aattgtactt agaaaatctt ttgaagaaaa aaagatttat acaaatgaaa tggaagaata
     6661 ttataaaaaa tattatctat acaatacagt atataatttg ttattaaatg caaagaaaat
     6721 ctatgcattt aaaagtgaat atgcgattaa tggttatatc caagagagta tattatatag
     6781 tatactttta aaaatctcac ataaaggaga taaaaattat gattaatata aattatagag
     6841 aagaccagat accaataata aattacgata atggtactat ggcagtacca gcagtaccag
     6901 gtgctggaaa aacatttata ataacaaatt tagtagctaa actattactt gaacagaaac
     6961 ataagagtgg taaaatatta attcttacat atatgaatag tgctgtaaat aattttaaag
     7021 gtagaataag aaagattctt gaagagaata aaatagatga tactaattcg tatgaagtaa
     7081 tgactataca cagtttggct gtaaaaataa taaaggaaaa gccagaagtt gtaatgttaa
     7141 gtgaggattt taacatagct gacgatttgc aaaaaagtat tatattaaat gaatgtataa
     7201 gtagatttag atttgaaggt ggagaaagag cttttagatg gtttttaaag gagcaaaaag
     7261 atgaacgctg gaaagaaata actcttgaag cctgggaaag aggttttttt gaatttgcag
     7321 gaaatgcaat aagtgaactt aagtataagg gaatttctcc agataaactt gaagaaatat
     7381 tgtcaagagg acacaaagga atgcttaaaa ttattttacc aatatataaa ttgtatgata
     7441 gaaaattaaa gcaaaatgga ttgctagatt atgatgatat attaatttta gcagaaaaaa
     7501 ctttaagctt agacgaaggg cttagaaaga agtttcaaac tagatacaaa tatatatttg
     7561 aagatgagtg tcaggactca aatgaaattc aaggtaatat aataaaaatt atatctagcg
     7621 aaaataaaaa cctagttaga gttggagata taaatcagag tataacagga acattttcat
     7681 catcagaccc taaatttttt aaagaattta taaatagtgc agatttctgt tataggatgg
     7741 atatgtcaaa tcgaagttca aaagatatac ttgatttagc aaacactctt gtcaagtatg
     7801 ttacaaagga atttagacaa gaagaatgta gacatgctct tgaagatatg caaataaaaa
     7861 ctgtgccaaa tggaatggga tataaagaaa accctaatcc agaacattat aatataaatg
     7921 taaagtggta tgagagttgg aaaattgaaa tagagcaaac tgctagatac gttaagggta
     7981 taaaaaataa atatccagat aaaagtatag gtatattggt tccatttaat gaacaagtga
     8041 cacaagttgc taaagaactt agagagaata atctaacctt tgaagaatta ggaccaaatt
     8101 ctttgaataa aaggaaggtt ataaacaaca tagcatatat tattgatttt atgttacatt
     8161 gtgatgatgt agaaaagtta atagttgtac ttaataaagt ttttatagat actgataatg
     8221 aagaagaaat aaagtatttt ttagaagaat taaaaaacta ttctaccgaa gaaattattt
     8281 ataattttga atttagtaag ttagataatg atttaataga atttaaagaa gaaagtgata
     8341 tatacttaag ttttaaaaga ggaatagata ttataaaaca gatattagaa tatccaataa
     8401 taaggttaga cctcttagtt ttgtttattg ggaaaaaact tagtttagaa aaagaagata
     8461 aagctgtact ggattatata tctttttata taaagtatct agtatcagaa aatataaata
     8521 tggatttaga agatgtatat aatttattgt ttgatgtaaa gaacagggtg tttaatcata
     8581 taatagatgt ggtatatgag ataaatggat atgaaccaga gcctggtagt ataacactat
     8641 gtaactatca taaatcaaag gggatggaat gggattgtgt gtttttacta ggtcttgttg
     8701 aatataattt ccctgacaat attaatcaaa agtttcagag tgataaatgg tatctaaaag
     8761 aaaaatataa aaaccctatg gcaattatta aatcagaagt tgaagctata ttaaaaggaa
     8821 gtatttcaac agattatgct cataaaacga agattgattc tataaatgaa aagattagac
     8881 ttttatatgt agggattact agagcaaagg aaatgttagt actttcagga agtgcttata
     8941 gagatgaaag tgatataggg aataagagaa aagagcaaaa accatgtata tatttaagca
     9001 gacttaatca acatattatt gaaaaaaggt caaattaata tataataagt tattaaaaga
     9061 ttgtttgaaa tatatctaaa agaggataaa acaatatgta cagtaagtaa ctactaaaaa
     9121 ataaagttaa gagagaagtg atatgagtga acgataaatt aaaatatttt tcttatagtc
     9181 aaaattcaat taacacatat aaatcatgtc cattgaaatt taaatataaa tatattgata
     9241 gaataaattg gaaaaatgat gatgttggta gtagagagta ttatgaaact ttaaaaacag
     9301 gaagagattt tcatttgatt tgtgaaagat attttagcaa tatacctctt ggaatctatt
     9361 ttaatgagga tgataaaaat agtaaaaagt ttttaaagtg gatggaaaat ataaaaaaag
     9421 ttgttcctat tgaaaaagga aaaacgtatt tgccagaata tgaagtaagg atgacattaa
     9481 atggggatat aatacaggca aagtatgatt tagttgtaat tggaaataac aatatagaaa
     9541 tatgggattg gaaaaccgag tctaaaaaga ttgactataa acacgtagaa aatagaatac
     9601 aaactattgt ttatatgttt ttagcaaaag aagtaatacc taaagtttta aaaatggaca
     9661 taaatgttaa agatataaat atgagatatt atcaacctga atttgatgac ttaccaatta
     9721 ccattttata tgatgaagaa aaacatgaag caaatagaaa taaaattcaa aattatataa
     9781 gtatgataaa aaacactaat tatgaagaac atacatacga agacaatcta tacaatgata
     9841 tagaaaaggt atataataaa gaagaacgta tgtgctatag aaataaaaag cattgcaagt
     9901 attgtgaatt taataagtta tgtaatggca aagaaataga ttatagtatt ttggaggcgg
     9961 aaatttatgg gacttaggtt tgtattaggt agaagtggaa gtggaaaatc cacctatata
    10021 ctagatgaga ttaaaaaaga agctcaaaaa aatgaaacga catcaattat acttttagtt
    10081 ccagaacagt acacatttga ggctgaaaat agagtaagta aactattttt aggaaaagaa
    10141 aaagataagt atctaagagt tagggtactt agctttaaga cactaagtaa tatagttttt
    10201 tcacaagtag gaggattgac agatgtaaat ataaattcta gtggaaaagc aatgatggta
    10261 tatagagcta ttgaagatgt aagtgaagaa ttaaatgtat tttcaaaatc aaaatcgcag
    10321 tctggttttg taagctcaat tacagatatg atatcagaaa tgaaacaata caatataagc
    10381 cctgaaatgt tagaaaatat atctggagaa ttggataatg aaactttaag tttaaaatta
    10441 aaagatataa gtaaaatata taattctttt gaagggaaat tgcatgaaaa ttatgtagat
    10501 gctcaagata tgttaacttc attggcaagt aaaattgaat taagcagtta tttagatgga
    10561 gcttgtgttt atatagatga atttacaggt tttacaccaa atcagtacaa tgtcataaag
    10621 agtatattaa ataagtctaa aagtgttaat atctctttga ctgtagatga tatcaactat
    10681 attgggtaca gtaaatctga tatgttttcc agaacgaaat ttacttattc aaaattgact
    10741 caattgtgca acgaagaagg cataaaaata ttgccacaag taaatttaaa cacaggtgtt
    10801 ataaaaagat ttgaaaaagt taaggaatta cagcacttag aaagatttta taatgcttat
    10861 ccatataaaa tatattcaaa tcaaactgaa aatataaaga taaaagagtt taacaattta
    10921 tattcagagg tggaagagat agccagagaa attgtacatt tagttagaga taagaatgtc
    10981 agatatagag atataaccat tgctacaaga gatttaaata gatatgattt tttagtacac
    11041 tctatattta atgaatataa tataccaaac tttatagata agaagagaga ggcaaaaagt
    11101 aatccaatag ttattttaat tatttcagct ttagaaatga agaatagacg atatgggtat
    11161 gaaactatgt ttaggtattt aaaaagtgga cttataggaa ttgataatga tgatataaat
    11221 ttactagaaa attatgtgtt ggctaatggg attaaaggta aaaaatggtt tgatgaaaaa
    11281 tgggattata gaataaccca aagtctttca ggtcaagaaa gtgaatttga actggaatta
    11341 aaagagaaaa taaatgaaat aaaaaataga gtattagagc ctatagtaat tttacaagaa
    11401 aaattaagag gaaaaaatag agtaaaagaa atctgtagat atatatatga atttttatta
    11461 gatataaata tgccagaaac tatagaaagt ttaataataa attttaagga taaaggggaa
    11521 cttgatgttg caaatcaata ctcacaagtt tgggacatag tagtggacat attagaccaa
    11581 atggtggaac ttatgggtga tgaaataatt tctttagaaa aatttataaa attaataacc
    11641 ttaggttttg atgaatatga attaggactg gttcctccta gtatagacca ggtacttgta
    11701 agtagtgtgg atagaatgaa aaatccagac acgaaatatt tatacctagt tggaactact
    11761 gatggtgtgt ttccgctgat tacaaaggat agtggaatat tgagtgataa tgatagggaa
    11821 agtcttggaa acaaaggaat cgaagttgat attgatagta agactaggag ttttgaagaa
    11881 cagtttcttg tatataaagc tcttacttcg acatctaaga atttaaccat aacatatcca
    11941 atatcagacc atgaaggtaa aacgcttaga ccatcaataa ttatatcaag acttaagaag
    12001 atatttccaa atatagaaaa taaaagttat ttagtggaag aaaataaaag cactgataaa
    12061 gatatactta aaaaaataac ggttaaatcc cctacattta atgaacttat aaacgtaata
    12121 aaaaattatg acagtgatgg ttacaataca gaagagatta atagtatttg gttagatata
    12181 tataggtact atttaaaaga tgaaatctac agttctataa caaaaaaagt tataaaaggt
    12241 cttagttata ctaatcaagt tcataagatt gaagagaaaa aaataaggtc attgtataaa
    12301 agtaattctc ttagcatatc taggcttgaa aaatatgctg aatgtccatt tgcttatttt
    12361 atacaatatg gtctaaaagc aaaaaagcgt aaagagtatt catttacacc accagattta
    12421 ggaactttta ttcataatat tttagatagg ttttcaaaag aacttttaca agataattta
    12481 acttggagag atattgatga aaaatatata gaattaaaga taggtataat agttgatgaa
    12541 ataattttaa agataccagg atatatatta aatagttctg agaggtataa ataccttgca
    12601 tatagattaa agaatatgtt gacaactgct ataactataa ttagtcagca aataaaacaa
    12661 ggttcatttg aaccaataga ttatgaagtt aaatttggca acaatggaaa atatccacct
    12721 ataaaaatgg tgttagaaaa tggacaagaa gtaagtttaa ttggacaaat agatagagtt
    12781 gatgaatttg aagaaggaga aaataaatat ataagaataa tagattataa gtcaggcaat
    12841 aagtccataa gtctaacaga aatatattat ggtctacaat tacaattact tgtgtattta
    12901 gatgcaatcc ttgaaagtgc aaaggatgaa gatataaata taaatccagc tgcaatacta
    12961 tattgtagaa taaataatcc aatagcaaaa tttaatgaag ataaagatga tgaagaaata
    13021 caagaagcaa tattaaaaga acttagaatg aaggggcttg tagtaaaaga ctctcacata
    13081 gttaaagaga tggataaatc attaatagat ggagaaagga aaaactcttt agtaatacca
    13141 gtaggtctta ctaaggatgg aaatgtaggt aaaagtactt cagcaataag ctatgaggat
    13201 ttcaaactgc ttagaaaata tgtaaggcat gctataaagg atttatgtga agaaatgtta
    13261 agtggagaaa tacgtatagc tccatataaa cataaagatg gaacatcatg tgacttttgt
    13321 gattactctg ctatatgtca gtttgattca actataaaag ataacaagta taaaaattta
    13381 aataataaga gtaatgaaga gataataaaa atgatgaaag gagatgttaa ttagtgagtt
    13441 ctcctaaatg gacaaaagag caattagaag ttatagaaag tagagaatgc aatttattgg
    13501 ttgctgctgc tgctggttca ggaaaaacag ccgttctagt tgagcgtata attcaaatga
    13561 taacaagtag agaaaatcca attgatatag ataagttatt agttgttaca tttactaatg
    13621 ctgctgcgtc agaaatgaga gagaggatag gggatgctat aggaaaagcc ttagatgaaa
    13681 acccagaaaa taaacattta caaaaccaac ttgttttatt aaataaatct agtattacaa
    13741 caatacactc attctgtttg gatgttataa aatcaaactt tcatagaata aacttagacc
    13801 ctaatttcag aataggagac caaactgaat gtgctatttt gaaacaagaa gcaatagagg
    13861 aagtatttga agatttatat gaagaaagag atgaggggtt tttaaattta gttgaaagtt
    13921 atgcagaaag aggaggagat aaagaagtac aagatattat cttgggaata tattcatttg
    13981 caatggcttc tcctgaacct aaaaaatggt tgattgactc agcagaacga tttaatattg
    14041 atgaaaattt tgatttttca cagtctattt gggctagagc tatattagat actgtaaaaa
    14101 tagagattaa tggtctttgt ctaaatatgg aaagggcatt aaaagaagtg gaatcaatag
    14161 aagaattaga aacttttgca gaaaagttat ccgttgaata taaaaaaatt gctgacattt
    14221 cacaagcatg taataaatct tgggatgagg catataaaaa gatggcaagt atgtcctttg
    14281 aaaattatgt aaaaggagta aaaagaattt caaaagatgc tccttcgtat ataaaagaat
    14341 caaaagaaaa ggcaaaaact ataagagata agactaagaa gtctttagaa agtatagtaa
    14401 gtgctacatt caataaagat aatgattcta ttagagaaga aataaaatat ctttataaca
    14461 tagttaaacc aatatctagt gttgtactga gatttgaaga ggaatatagc aataagaaaa
    14521 gagaaaaagg aataatagat tttaacgata tagagcattt tgcattaaat atacttacag
    14581 atgtagatga aaaaggtaat attgtacctt ctgatatagc agttggatat agaaacaagt
    14641 tttatgaaat atttatagat gaatatcagg atagtaatct agtgcaggaa gtactgctta
    14701 aagctgttgc aaatacagaa actccaaata gatttatggt tggtgatgta aaacagagta
    14761 tatatagatt tagacaagca aagccagaat tatttttgca aaaatataat aactataatg
    14821 ataaaaaggg aagctcccat agaaaaataa tgctttacaa aaactttaga agtagagaag
    14881 aagttgtaga tgctgtaaat tatatatttg aaaatataat gaatgagaat ataggagaaa
    14941 ttgaatatac agaaaaagaa agactaaatt taggtgcaaa ttttaatgtg gatacagacg
    15001 agaaatctat tattggtgga gcaacggaga tacacctaat acaaaaagat aataaacttg
    15061 atgatgatat tataaatgat aaagacgata gaattaataa caaagaaaat gaaatagagg
    15121 aagaagaaaa attagataat atacaacttg aggctagaat ggttggaaac attatcaaag
    15181 atttaatgaa agtcaatgaa gatggaaaaa ttcaaaaggt ctatgataag ggaatagatg
    15241 gatatagacc tgtggaattt agagatatag ttattctttt aagagctaca tctgcatggg
    15301 ctccagtgtt tgcagatgaa ttgatgaata tggatatacc aacgtatgct gatgttggag
    15361 tggggtattt tgatacgatt gaaataaaaa caatattgtc attacttcaa ataatagata
    15421 atccaatgca agatatacct cttatatctg tattaaaatc acctatattt ggatttacac
    15481 cagaggattt gattgatatt agagttcaga gtaaagataa aattttttat gaggttttaa
    15541 aaagtacagc agagtatgat ggatttacag attctcaaaa tgaaaatgag tctgagttta
    15601 taccaagtga agaatgcata aacaaaagta aagatttttt aattaagcta aaggaattta
    15661 aagaaaagtc aatgtacatg agtacagatg aatttatatg gtacttgtac acaaggactg
    15721 gatactatgc ctatgttgga gcattgccag gtggaagtca aagacaagct aatttaaaag
    15781 tattgtttga gagagcaaaa caatttgaag aaaccagtct taaaggaata ttcaactttg
    15841 taaattttat agagaaatta aaaaaatcta gttctgatat gggaagtgca aaaacacttg
    15901 gtgagaatgc aaatgttgtt agaataatga gtattcataa aagtaaaggt ctagaatttc
    15961 cagtagtcat atgctctgca atgggtaaaa atttcaatac tcaagatttt aaaaagagta
    16021 ttttatatca tcataattta gggtatggac ctcaatttgt agactatgag agaaggattt
    16081 cttttccaag tatagccaaa gaagcattaa aaagcaaaat aaatatagaa aatttatcag
    16141 aagagatgag agttttatat gttgcattta caagagctaa agaaaaattg attataactg
    16201 gttctactag aaatatacaa gatagtataa agagatggtc aaatggaatt gaaagtttag
    16261 atacaatatc acaatacgag atattaaaag gtaaaaattt tttagattgg ataatgcctt
    16321 gtgtattaag acatagggat ttatctaatc tactagaaga agtaggatta gacgcagttt
    16381 ttaatgttga acataattca aaatggtatg gaaagttgtg gaataagagt gatattttag
    16441 tggaaaagaa gagtgatgaa gaaaaagaaa gtattgaaga aattcttgaa aaaatagatg
    16501 tagataatcc tgatagtgat tattacagtg aaatagaaga aaaattaaac tatatatatc
    16561 catatgaatt tagtacaaga aaacctgcta ctatatctgt tacagaaata aaaaagatac
    16621 aaaataatta tgaagaagag ttaataaata ctatatttga acaaaaagta atattaaaaa
    16681 agcctctatt tattcaaaat gaagaagaaa gagaaaaaat aagtggaaca gaaagaggta
    16741 caatagtcca tttagttatg gaggttttag acttaaaaaa tgtaagtagt gtaaatgata
    16801 taaaatcaca aataagaggt tttgtttcaa aaggtataat aacagaaaaa caagctagta
    16861 tagtaaatcc atataaaata tataaatttt ttgcctctaa cataggaaaa agaatgttga
    16921 atgctgaaat tataaataga gaaaaatcaa tttatgcaca agtaaatatg aaagacatat
    16981 atatttatga aaagcttata aacaatgacg ataaaaaact ttatgataat gaaagtgtca
    17041 tgttaagagg tatagttgat gcttattttg aagaagacaa tcaaatagtt ttggtggatt
    17101 ataaaacaga ttttgtaaat gaggaaaata taaatcaaat aatagagaaa tataaaaaac
    17161 agttggattt atatgcagat attattgaaa ctttaactgg taagtcagta aaagagaaat
    17221 gtatatattt atttggagtt gatgaagctg tttgttatta gtttttatat ataaattaaa
    17281 cctaaaagat agaggaaggg gaaaaaatga gatttattca tacatcagat tggcatctag
    17341 ggaagtccct agaaggccat tctagaattg aggaacaagc aaagttttgt gaggaattta
    17401 taaaaatagt agaatcaaat gaaatagata tggttataat tgctggagat gtatatgata
    17461 cttctaatcc accagcacaa gcagaaaaac tattttatca gactgtatca agacttgcca
    17521 ataatggtca gaggtgtgta ttaataattt caggaaatca tgataatcca gagagactct
    17581 ctgcaataac acctctagca catgaacagg ggatacttat atatggttat ccattaagtg
    17641 ctacgataga agctaagtat aaagggtttg aaataacata tgcaactcag ggatgtacaa
    17701 aactgaatat aaatggagaa aatattgtgg ttgctacatt accttatcca agtgaaaaaa
    17761 gattaaatga agttttttca agtgaagatg agtttgagaa acaaaaaaat tattctgaaa
    17821 aggtaggaga tatatttaga agtttagaag aaaattttag aagtgatact ataaatatag
    17881 ccgtatcaca tatatttgta ataggtggag agagtactga atcagaaaga cctatacaat
    17941 taggtggaag ttttttagtt gaaagaaaag atttgccaga aaaggctcaa tatactgcac
    18001 taggtcattt acataaacaa caaaaagctt ccgaacgttt aaatgcatac tattctggtt
    18061 ctccacttca atatagcaag gatgaaagag cgtataccaa aggggcatac atagtggata
    18121 taaaagctgg tgaaaaacca ataattgaag atgtatattt taataattac aaacctatag
    18181 aagtatttaa atgtaatgga atagaagaag cactagatat atgtgagcaa aatcaagata
    18241 gagagatttg gtcatatttt gaaataaata ctgatgagat aatatcacag aatgaaatta
    18301 aaaaaatgaa ggaactatta aaagacataa tagaaataaa accaataata acatcttgtt
    18361 atgaacaaga aagtgtagat ataaaagaaa agtctatggc agagttgttt agagagttct
    18421 attcttttag taaaggtgta gagccaaaag gagaacttat ggatttattt ctagatataa
    18481 taagtgaaga aggtgaatca gcagatgaga ccaattagat tagaacttac agggcttaat
    18541 agctatattg ataaacaagt tatagacttt gaaaaattaa ttgaaagagg tttgtttggg
    18601 atatttggaa ctactggaag tggaaaatct acaatcttag atgcaataac tattgctatg
    18661 tatggaaata tatccagaaa tacaaaagaa tatataaaca gtgtgtgcga taaggcaatt
    18721 atatcatacg agtttgagat aggaagcaaa aacactagaa gaagatacat tgtagataga
    18781 accattgcta gaagcaaaac aggaacaaag acctctaatg ctagattaat agaagtattg
    18841 aatgacaata cccaaaatgt tttagctgat aaagttgtgg aagtaaatga aaaagtagcg
    18901 caggtcgtag gattaacggc aaatgatttt actaggtcag tagttttacc acaagacaaa
    18961 tttaatgagt ttctaagatt atcacgtgca gatagaagag acatgttaga gagaattttt
    19021 aatcttgaga aatatggaag aagtcttggc gaaaaagtga aaaagagaaa aaatatacag
    19081 ttacaaaatt taaaagattt gaaatcaaaa ttaagtcaat atgatggaat tacagaggaa
    19141 gtatataaca atataaacca agaattaata gagttaaaaa atttggaaaa agataagaat
    19201 aatgctttag acctagctca aaaatcttat gaagaaagta aaacagtata tgaagaacaa
    19261 ttaaagttag aaaaaaatga acttagaaaa aatgagcttg atttaaaaaa tagtgagata
    19321 aaagaaaaga ttgctcttgt agaaaatgat agtaacgcta aaaaggtaga cccatacata
    19381 agttcagttc aaaatctaga aaaaaagata gatgaagata gcttcgcagt aagtaattta
    19441 gaaaagaaat tagcaatatt aaatcaggag cttgaagtta caaaaaatag atatgaaaaa
    19501 ataaacaaaa ttaagaatga agaaatccct aaattgagtg aagaaaaaat aagattgcaa
    19561 caagcaataa aattagaaga agagttagtt ttattagata gagagttaaa agagctaaaa
    19621 gaaagtggaa ttaatttaaa taagactaaa gttgaattag aaaaagtaaa gcaggtgtca
    19681 gagtccagaa aagatgcagt tactaaatct ataaaagaag ttgaaggaaa gattgataaa
    19741 gtaaatataa gtgcagaatt aaaacaaaaa atatttctag catatgaata cgagaaagat
    19801 tacaacaacg tattggaaga aaaaaatcaa aagctaaata aactagaaga aatactcaaa
    19861 gagacagaaa atataaattt aaaagttaga tatattgata aagataagaa tgatgtaaat
    19921 cgtaatttag aaaatttatc acttcacttg gatgttcttc ttaaaaaatg tcctggtaag
    19981 agtgctgatt tacttttaaa atctgaatat gttactgaat taagaaataa agcaaataat
    20041 actaaagaaa atgaaattaa gaaaagcagt atacaagatg aattaaagat aatacttgaa
    20101 agtaagttta atactgaaag ggaagtaaat ttactaaatg aaaaacttga aaataataga
    20161 aagaacagag atgacttaga aaaagaatta gaagaactaa agtatttaaa tttagcctct
    20221 gaacttagac gtgaattaaa agaaaatatg ccttgtccag tttgtgggtc aaaacatcat
    20281 gaaaatcatg atataactaa gtatgatgaa aatatatctt ttgtcaaaga aaaactggag
    20341 aaattagaaa aagaaaaaat aagtataaga aacaatatag aggaattaaa tgctaaagta
    20401 agtgggtatt tatctataga aaaaatgaag actaaagaac ttgaagatgt aaaaggaaaa
    20461 ctagggggga ttccatctag tcaattatta
//
LOCUS       DAGQVA010000074        20309 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.074, whole genome shotgun sequence.
ACCESSION   DAGQVA010000074 DAGQVA010000000
VERSION     DAGQVA010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20309
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.074"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..491
                     /locus_tag="MIV85_002944"
     CDS             <1..491
                     /locus_tag="MIV85_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBY2962271.1"
                     /translation="NKLAKLQRELSRKTIGSLNRNKARLKVAGLQEHIANQRNDFLQK
                     LSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWYGRKIVKV
                     GKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQ
                     NK"
     gene            609..914
                     /locus_tag="MIV85_002945"
                     /pseudo
     CDS             609..914
                     /locus_tag="MIV85_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            927..1832
                     /gene="truB"
                     /locus_tag="MIV85_002946"
     CDS             927..1832
                     /gene="truB"
                     /locus_tag="MIV85_002946"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBY2962272.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            1963..2892
                     /locus_tag="MIV85_002947"
     CDS             1963..2892
                     /locus_tag="MIV85_002947"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBY2962273.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            2996..3253
                     /gene="rpsO"
                     /locus_tag="MIV85_002948"
     CDS             2996..3253
                     /gene="rpsO"
                     /locus_tag="MIV85_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBY2962274.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            3493..4338
                     /locus_tag="MIV85_002949"
     CDS             3493..4338
                     /locus_tag="MIV85_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBY2962275.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            4463..6574
                     /gene="pnp"
                     /locus_tag="MIV85_002950"
     CDS             4463..6574
                     /gene="pnp"
                     /locus_tag="MIV85_002950"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBY2962276.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            6840..7583
                     /locus_tag="MIV85_002951"
     CDS             6840..7583
                     /locus_tag="MIV85_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBY2962277.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            7741..8988
                     /locus_tag="MIV85_002952"
     CDS             7741..8988
                     /locus_tag="MIV85_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBY2962278.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGI
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            9023..9268
                     /locus_tag="MIV85_002953"
     CDS             9023..9268
                     /locus_tag="MIV85_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBY2962279.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGDILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            9278..10501
                     /gene="dapG"
                     /locus_tag="MIV85_002954"
     CDS             9278..10501
                     /gene="dapG"
                     /locus_tag="MIV85_002954"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBY2962280.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            10614..11348
                     /locus_tag="MIV85_002955"
     CDS             10614..11348
                     /locus_tag="MIV85_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBY2962281.1"
                     /translation="MKDYREDNEKFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            11471..13882
                     /locus_tag="MIV85_002956"
     CDS             11471..13882
                     /locus_tag="MIV85_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBY2962282.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            13885..14943
                     /gene="mnmH"
                     /locus_tag="MIV85_002957"
     CDS             13885..14943
                     /gene="mnmH"
                     /locus_tag="MIV85_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBY2962283.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            14937..16271
                     /gene="rimO"
                     /locus_tag="MIV85_002958"
     CDS             14937..16271
                     /gene="rimO"
                     /locus_tag="MIV85_002958"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBY2962284.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            16258..16800
                     /gene="pgsA"
                     /locus_tag="MIV85_002959"
     CDS             16258..16800
                     /gene="pgsA"
                     /locus_tag="MIV85_002959"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBY2962285.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            17088..18134
                     /gene="recA"
                     /locus_tag="MIV85_002960"
     CDS             17088..18134
                     /gene="recA"
                     /locus_tag="MIV85_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBY2962286.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGISVSKEIVEE"
     gene            18310..19851
                     /gene="rny"
                     /locus_tag="MIV85_002961"
     CDS             18310..19851
                     /gene="rny"
                     /locus_tag="MIV85_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBY2962287.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
BASE COUNT         8318 a         2051 c         3905 g         6035 t
ORIGIN      
        1 taaacaagct tgctaaatta caaagagaat tatcgagaaa aacaatcggt agtttaaata
       61 gaaataaagc aagattaaaa gttgcaggac ttcaagaaca tatagctaat caaagaaatg
      121 attttctaca aaaactatct actaaattaa taaaagagaa tgatattatt tgcatagaag
      181 atttacaagt aaagaatatg attagaaatc gtaaactatc tcgcttaatt tcagatgtat
      241 catggtcaga atttattcgt caattagaat acaaggctaa ttggtatggt agaaaaattg
      301 taaaggtagg taaattcttt gcaagttcac aaatatgcaa taaatgtggg tataaaaacg
      361 aggaagttaa ggatttaaat ataagagaat ggatttgtcc tagttgtaat gaaactcacg
      421 atagagatat aaatgcaagt ataaatatat taaaagaagg attaagacta ataacgattc
      481 aaaataaata acttatgtaa gaaccgtagg aactacgggg atagcctgtg gagaattagt
      541 aagacatatt ttaatatgca aaattctgtg aagcaggaac cctgtgactt tagtcatggg
      601 aggttcagtc aaaggtatct agtatagttt taactcaaga catgatgaat agaaataata
      661 ttagctttaa tgatgttgat ggaataacaa catatacaag agacataaaa ggtatagaag
      721 ttggaatttt atttaaagag aaaaaacaaa atgaaattaa agtgagtttt aggtcaaaaa
      781 attatgttga tgtaagtgaa atagccaagt tatttggtgg tggtggtcat gtaagggctg
      841 ctggatgtac tattagagat agtattgata atgcaaagaa aatggtacta gaggcagtgt
      901 taaaatcaat ttaaggtgac agtaaaatga ataagattat aagtatattg aaacccacag
      961 gtatgacatc tcatgatgtt gtaagtagag tgagaaagat tttaaatata aaaaaagttg
     1021 gtcatacagg tactcttgac ccagatgctt caggtgtttt accaatctgt atagggaaag
     1081 ctacaaaagt atgtgaagtt attttaaaca aagataaatc gtatatatgt gagcttactt
     1141 taggtataag tacagatact tatgatgctt caggtgaaat tttaaaaaaa gttgatgatt
     1201 ttaaatttag taatgaagac atagaaagag cttttgacac acaaagagga gagataaatc
     1261 aacttcctcc aatttattca gctttaaagg taaatggaaa gagaatgtgt gatttagtaa
     1321 gaagtggtag acaatctgaa attactttaa aaacaagaag agtaaatata aaagacataa
     1381 aaatactaag tataaaaggt aataaagtaa tgttttatgt tgagtgttct aaagggactt
     1441 atgtgagaag catttgccat gatataggag aatatctagg ttgtggagct catatgtcgt
     1501 ttttgaatag aacatcttct ggtaaatttg acttagataa ttcaataaca ttagaagaat
     1561 tagaattatt ttatgaaaat aaaactttag acaaatactt atatgatata gattatgtcc
     1621 ttgattcgtt taattatgtt gtattaaacc ctaatgctat aaaatattat agtaatggtg
     1681 gctcaataga tgataaaagg tttttaaaaa ataatttcga taaagatgat gaatttgtaa
     1741 gagtatacag tacagataat ttcttaggat taggaaaatt atcaaaacac aataatacaa
     1801 taagtgttaa aagtgataag atgttcatat aaccaatgta tttaaaaaaa caacaaaaga
     1861 gatagtacta taataacttc tatagtctat ctcttttact tatgctataa tagtttgtga
     1921 ataagttaag agtaaattat attttagcgg ggaacattta ttatggtgat tataaaatct
     1981 ataaaagaaa tagcaaacat aaaagaaagt gtcattacca taggaaattt tgatggtgta
     2041 cacaaaggac atcaagttct tataggaaaa acagttgaac atgcaaaaaa agaaaatata
     2101 cagagtatcg tatttacatt tgcaaatcat cctgtaaatt actttagacc aaactcaaca
     2161 aaaaatatta taagcaatga tgataaaata aaattattag aagatttggg aatagatata
     2221 gttgtaatca taccatttga tgagtatatg actaaaatac ctgcaaagga tttcgtagat
     2281 gagatactag taaaaaaatt aaaagctaaa aagatagtaa ttggacatga ctttacattt
     2341 gcaagggcaa aagaaggcaa tgttaatcta ttaaaaagct tagaacatga atttggtttt
     2401 gaggtagaag taataaaacc catcaaaatc aatgatgtaa gagtgagtag tacttatatt
     2461 agaagtttag tatcccaggg tgatatggct aatgtcaagg aatatttggg tagaaattac
     2521 aagttagaag gttgtgttat acattctaaa caccttggaa gaactatagg attcccaacg
     2581 gcaaatattg accttaagaa taatatgctc gttccaaaga gaggtattta tgcttctatt
     2641 gtacatattg gagatgagac ttattttggt gctacaaatg taggctataa cccaacagtt
     2701 aatggaaaaa ctttgtctat tgaaacaaat attttagagt ttgatagaga tatttatggg
     2761 gaaaatataa ttgttgaatt tttggaaaga ataagagatg aaagaaagtt taattcaata
     2821 gatgacttaa aaaatcaatt gtataatgat acaaattatg tgtatgaaaa ctatgtttgc
     2881 aaaaacaagt aatgtatgat aaaatgatta aggaaaataa ccattactca gcatttgaat
     2941 actccaatca atgcttagta ataggcgttt ctaaaaaaat acggaggtaa tctaaatgat
     3001 aaacaaatca gaaataataa aagaatatgg aagagctgaa ggggatactg gttctccaga
     3061 agtacaaata gctttattaa cagctagaat aaacgagtta aatggacatt taaaaactca
     3121 taagaaagac caccattcaa gaagaggact attaaaaatg gttggtagaa gaagaaactt
     3181 attagcttac ttaaaggaaa aagatcttga aggatataga gcattaatag ctaaattagg
     3241 attaagaaag taatttcatt ctttataaaa aagcaggtat agtgtatacc tgctttttta
     3301 tagttaattc attataaagt aaaatagtta ataataaaag tagtttatat gttataaaaa
     3361 attataaaat gaataatatt gggtaagaat attaaaatag tatacaaata cataatcaat
     3421 ttaaaaggaa agacaggata aatatagaaa ttttataaca ggataattag ttggaataag
     3481 gaggatatta ttttgaaaat aaagttagta tgcgatagtt tgtgcgatat tccagatgaa
     3541 atatcagaaa aagattatat agagatagtt ccacttacag ttatttttaa tgatagggaa
     3601 tatatagaag gagtagatat aaagaaagaa gagttttata aaaaagtaaa agaaatcaag
     3661 caaataccta aaacttcaca agctacatat atggagttta aagaagtgtt tgataagttc
     3721 ataacagaag gttatcatat aatctgtatg acaggggctg caaacgcatc aggaactttt
     3781 caaagtgcta tgatagctaa aaatgatgta aatgaaaatg aaaaaataca tatatttgat
     3841 actagaaatt tatctctagg tagtggacaa tatgttataa aggcatgtga acttcttgaa
     3901 gaaggactgg gatttgaaga aattatagat gaattagaaa atactcgcag tagtgtaaga
     3961 ttgctttttg caccatatac acttgatttt ttaaagcaga gtggaagagt tccagttgca
     4021 actgctttga taggaaatat gttaaatata aagcctatat ttttctttga taatggggaa
     4081 gctaagttgg taaataaggt tagaggaata aagaatatag caagtaaatt ggtcgatata
     4141 attttagaaa tgaatgaagg gtctttagaa ggaaaaatcg tcacaatagg ttgtggagat
     4201 aatttacacg attgtgaaat attaaaagat gaagtaaata aaagaataaa agcaagaaga
     4261 gtattattta ctcgaggagg agtttctatt tgctctcata cagggccaga tatattggct
     4321 ataagttgtt ctaattagta gtaatataag gtttttgcat atatatgtga agataatttt
     4381 atattgttaa tttatagtat ttttgataat atagtaaata gagtgatata cgtgtttttt
     4441 aataagagga ggacaagcat taatgtttga acataaaata tttaaaatgg attttgcagg
     4501 aagagaactt tctgtagaaa taggaaagat ttgtgaaatg gctagtggta gttgtatagt
     4561 tcgatacagt gatagtatgg taatggtaaa tacaactaaa tcagccaaac ctagagacgg
     4621 aatagacttt tttcctttaa gtgtggatta tgaagaaaaa ttatactctg taggtaagat
     4681 acctggaggt tttttaaaga gagaaggcaa gccttcagag aaagctatac ttacatcaag
     4741 attgatagat agaccaataa gacctttatt cccaaaagga tttagaaatg atgttcaggt
     4801 agttgcaaca gttctatcag tagaccaaga ttgtacacca gatatagtag caatgatagg
     4861 ttcttcaata gccctttcta tatcagacat accatttaat ggaccaacag gttcagtatg
     4921 tgttggcctt gtagatggtg catttgttgt aaatccaaac gcagagcaaa gagaaaaaag
     4981 ttcaatgcat ctagttgttt caggtacaaa ggaagcaata atgatggttg aagccggagc
     5041 tgatgaagtt ccagacgagg taatgcttga tgctatttta tttgctcacc aagaaataaa
     5101 aaaaatagtt gagtttatag aaggtatagt tgcagaagtt ggaaaagaaa aaatgcctgt
     5161 tgaattatac catgcaggag aagaaataac tcaattggtt cgcgaatttg caactgataa
     5221 gatgaaaaaa gcagttcaga cttttgaaaa gttagagaga atggaaaata tggatagagt
     5281 taaagaagaa actttagctc actttgaaga aactttagaa gattttgaag attttgttgg
     5341 agatatagaa gaagtattac aagatataat aaaagaagaa gtaagaaaac ttatagtaca
     5401 tgaaaatgta agaccagata atagaaaact tgaagaaata agacctatat ggtgtgaaac
     5461 tggcatgata cctagagctc atggttcagc catatttact agaggacaaa ctcaagtact
     5521 taatgttgct actttaggtg ctttaggaga tgttcaaaaa ctagatgggt tagatgaaga
     5581 agaaaacaag agatatatgc atcattataa tttccctgca tatagtgttg gagaagctag
     5641 accatcaaga ggaccaggaa gaagagaaat aggacatggt gctttagcag aaagagcttt
     5701 attaccagta ataccatctc aagaagaatt tccttatgct attagattag tttctgaagt
     5761 attaagttca aatggttcta catctcaagc aagtgtatgt ggctcaacat tatctttact
     5821 tgatgcaggt gtacctataa aagatatggt tgcaggtata gcaatgggac ttataaagca
     5881 tgatggtaag gttgcagtgc tttcagatat acaaggtatg gaagaccatt taggcgatat
     5941 ggactttaaa gtagctggaa cagagtatgg tataacagca atacaaatgg atataaaaat
     6001 tgatggtata gataaagaaa ttctacaacg tgctttaaaa caagctaaag agggtagaat
     6061 ccatatacta ggagagatga gaaaaactat atctcagcca aaaccagaac tttcaccata
     6121 tgcacctaag attgttaaaa tgcaaataaa tcctgacaag ataaaagatg taataggacc
     6181 tggtggaaag ataataacta agataataga cgaaactgga gttaagatag atattgaaca
     6241 aactggggaa gtatttatat caggtattga gattgatatg attaagaaag ctcaagaact
     6301 tataaataat atagtagttg aaccagaagt aggaaaaact tataaaggta aggtaagtag
     6361 aataatgaac tttggagcat ttgttgagat acttccagga aaagaaggat tacttcatat
     6421 atctcatata gctcatgaaa gagttgccaa agttgaagat gtattgaata taggggatga
     6481 agttgaagtt aaagttacag agattgatga aaaaggaaga gttaatttat caagaaaagt
     6541 tcttttacca aaaccagaac ataaaaataa ataacttatt atataattaa aagcaaagtc
     6601 ttaggatttt gcttttttaa atacaaaaaa gtagataatt ttaaaatgat agttatggat
     6661 ggcttatagt tctttttctg tcaggcttta ctcttataaa gaagctattt aaaagctgat
     6721 taatagagag ctttattgat atatatagaa tcacttaagt tatatttagt gcataaacag
     6781 agcttatttt taatagtatt aaataagaaa caatttgtac ataattaggg ggagttttaa
     6841 tgataatgat ggtacttaat aagagtaagc tcaaaaaaat cataatacta attttagtag
     6901 tgttattagt attatcagga ggggtaatgg tattaaagtt atttaacaac aagccagtat
     6961 ttaatttatt taatggtgta gatttaccat atgaaagagg tacaaaggat aaaagtggat
     7021 atgttgcatt aacctgtaat atagaccttg gatgggaaac agagtacgta gaatccattt
     7081 tagaaacact taaaaaagaa aatgtaaaga ttacatttaa tgtaactgga aaatgggcag
     7141 aaaagaataa ggatgaatta ttaaagataa aaaaacaagg acatgaaata ggtaatcatg
     7201 gatacaaaca tttagattat tctacattat catatgaaga caattatgag caaatagaga
     7261 cctctaaaaa gataattgaa gaaattatag gtgaaaaaac taaatttttt caagcaccag
     7321 caggttcttt tggtccagaa acagtaaagg ctgctaaagc attagggtat acttctatca
     7381 aatgggatgc cgatactata gattggaaat acaaagacca accagaggta atcattgata
     7441 gaatgaagaa aaaagacatt aaagatagta gtataatttt aatgcatcca accaacgcaa
     7501 cgacaaaatg tatagatgat attatagcta ttgtaagaga aaaaggacta aaaccaggaa
     7561 aacttagtga tgtatttaag tagacaaagt ataaatattt ggttaagatt gtataagttg
     7621 tagttgaatt aattaaaaga ctgacttata atgtaataca tataaaaaat aaatataatt
     7681 aaaacatagt gttttcaata atccaatatg aaacaaagaa taaattgtta ggagaatgta
     7741 atgtataaga caaaaatact ggaaaatggg cttacaataa ttggtgaaga aataccatat
     7801 ctaaagtcaa taacattagg tatttggata aatgcaggct ctaggataga agaagcacag
     7861 gtgagtggaa tttctcattt tatagagcat atgatgttta aaggaaccaa aaacagaaca
     7921 tcaaaagaga ttgctagttc aatagataat ttgggtggtc aaataaatgc atttacaagt
     7981 aaagaatgta catgttatta tgtaaaacta atagatgagc atatagatac aggaattgat
     8041 gtattgagtg atatgatact aaattctaaa tttgataaaa atgatataga taaggaaaga
     8101 cttataatat tggaagaact taagatgtat gaagactctc cagatgactt atcttatgat
     8161 ttattagtgg aaaatatata tgctaatgat ggattaggaa tgaatataat tgggacaaaa
     8221 gaatctctgt acaatataac tagagaatcc atgttagaat acttaaataa gtattatatt
     8281 ccaaataacg ctgttatttc tatagctgga aactttaact ttgatgatat ggtggagaaa
     8341 atcaaatcaa aatttggaca ctgggaaaag aaaaatttaa gtatagacat aagtgaggct
     8401 aagtttaatc cttgctttat atcaaaaaat aaagatactg aacaggtgaa cttagctatg
     8461 tgcctaaaag gtattccttt tgaaaatgat gaagaagtct attcaatggc agtggtaaat
     8521 aatattttcg gtggaagtat aagctcaagg ctttttcaga aaataaggga agaaaaaggt
     8581 ttagtatatt caatatactc atcacagaca ttatatagga aatgtggtga attaggtata
     8641 tttgcaagca tgagtacaga aaatttacaa gatgtatata atttaataaa gaaagaaatt
     8701 gaaaatataa gagaaaacta tcttacagaa aaagaaatat ctgaaagcaa ggaacagtta
     8761 aaaggaaatt atatattgga tttagaaagt actagcagta gaatgatgtc tactggtaaa
     8821 tctatgttac ttagcaaaaa agtaaaaact acagatgaaa tacttgaatg tataaataat
     8881 gttaatatta attcaataaa gaaggttgtt gataaggtat tcaatatcga aaatattggt
     8941 acatgtatag ttggaagaga tgtagaaaag attctacact tggattaata ttgaaaaaag
     9001 taaatctctg gaggtataaa atatgaattt atctgaaata gcaggtaagg aaatagttaa
     9061 cttggtcaca ggagaaagat tgggggtcat tggagaatgt gaccttatac tagatgaaac
     9121 tacaggcgat atattagcgc ttctaattcc aaaagaaaaa ggattttttg ccagaagaaa
     9181 agataagtca tttttagaag taccatggag aaatgtaaaa aaaataggta atgacatgat
     9241 aattatagaa tatgagggat atatttagga ggaaaaaatg agtattttag tgcaaaagtt
     9301 tggtgggaca tcagtagaat catatgaaaa aatgaatgaa gtatgtaaga tagtaaaagc
     9361 atacaaaaaa aatgatgaag aattacaatt agtattagta gtttcagcaa tgggaagaaa
     9421 aggagctcca tatgctacag atacacttat aaatttgtgt agtgcagtaa atgatgagcc
     9481 aagtaaaaga gaacttgatt taataatgtc ttgtggagaa ataatatcag gaacaattct
     9541 tgctaattta ttgaatgcac aggggataga ttctgttttc tttactggtc agcaagcagg
     9601 tataattaca agtgatgaat attctaatgc aaagataaag tatataaatc ctaaaaaggt
     9661 aaaaagagct ttagatgatg gtaaggttgt agttatagct gggttccagg gtgtaacaga
     9721 tgatggagaa ataactactc ttggaagagg cggaagcgat acatcagcag ttgctattgg
     9781 taaagcttta gaatgtgaaa cagttgaaat ttacactgat gtggatggta taatgactgc
     9841 agaccctaga gtagaaccaa acgctaaagt attgagtttt atagactatg aggaagtatt
     9901 ccaaatggct gacaaaggtg caaaagtaat acatccaaga gcagtacagt tggctaaaag
     9961 tggaaatata actttagcca taaagaatac aatgaatcca acttttgaag gtacaaaaat
    10021 aggttcttta tgtagacact tagaagacaa tatagaatat gaacaagaaa gagattttaa
    10081 ggttgctgtt gcaaataaag atagcgtagc acaagttaag attaagtcag cagaagaagt
    10141 gtttacagaa gtattaaatg agatagaaaa gaaacttata actatagata tgataaattt
    10201 ctttatatca gaaaaagcat ttgttgtaga agatgctgat ataaaatcat taaaggaaat
    10261 actagataaa tttgaattag attatgaagt aaatagagac tgtgctaagg taacattgat
    10321 atgttcaaga attgctgatg aaatgtctgg tatcatgtca aaggtagtta gaggattatc
    10381 aaaagcaggg gtatctcttt tacaaacatc agactcaaat atgactatat cttgtttagt
    10441 tagtgaagaa gatatgcata cagcagtaca tgctatacac caacaatttt atttaaaata
    10501 aactgtataa tacaattatt ttttaatcaa atttaagaat ttcatatata tcttaatata
    10561 tttgatttat ttggtaaaac taaattaaat ataattttga taggagtttt tttatgaaag
    10621 attatagaga agataatgaa aaatttgata aagataattg tagtgaagaa tctagttgcg
    10681 aagagagaga atgtataaag caatttggta ccaatgaaat gccacctcaa cctcctaaag
    10741 atattcaatg tataactata attggagaaa ttgagggaca ttttatagga aatcctcaaa
    10801 aaaaagctac aaagtacgag catataattc caatgctata ctcaattgag gaaagtaatg
    10861 atgttaaagg agtgttagtt gttttaaaca ctgttggagg agatattgaa gcaggtttag
    10921 ctattgcaga acttttaaac agtacatcta aaaaagtagt tactcttgtt ctaggaggaa
    10981 gtcatagtat aggtgttcct cttgctacag caggagatta ctcatttata gcaccaacag
    11041 caaccatgat tatacatcca gtgcgaacta ctggtcttgt gattggtata aatgagactt
    11101 ttgaatattt taaaaagatg caagatagaa taattcaatt tataataaga acatcaaata
    11161 tcaaaaaaga tgtacttgaa aaacttatgc atgaaaaaga tgaacttgta agtgatgttg
    11221 gtagtgtatt aataggaaaa gaagctgtgg attatggtct tatagatgaa gttggaggac
    11281 taaaagaagc acttaaaaaa ttaagagagc ttataaaaga atctgaggaa gaaaaaaata
    11341 atgattaaaa tttgtttaaa taataaaatt tatgatataa tgatgtaata aagtaggagt
    11401 gttagtgtta aggcattagc actttttgct gtgaaggggt aaaacttgct aaaaataagg
    11461 agtgatatta atggccacga aaaagaagaa aaaaaagaag gtaaatacct taagttttaa
    11521 tgcagaatat cataatttaa taacaatatt tataggtgta tttttattat atagtttaaa
    11581 ttctaattct atgggatgga tacctgtgtt aatgcaaaat ctttttaagg gactatttgg
    11641 agggctttca atagcaatac catttatagt aattataaca ggacttttag gattttttga
    11701 tggaaatgaa tatatatata ggctaagaaa gactaaacta tactacataa ttattttatt
    11761 tatatttgta ttttatggat tattaaatgc aggaactctt cctgtagata gcccactaaa
    11821 aggtaacatg tttgatgatg ttatgaaatt gggtgtaagt ggacaaggta gtggtttgat
    11881 agcaacaact attgcgtatt atatgagtaa aatatttggt atagcaggtg gatggttaat
    11941 aagtatcttc gcacttatac tttctgtaat gtttatattt aatatttcta taaaagattt
    12001 ggtgtcaaat gcaaaatcaa aatctaaagc atctaaagac agcaatttaa cgtttaaaga
    12061 taaaattgca aatatgaaaa aatctgcaat agatatgatg actgatgaag tagatgatac
    12121 tactataaat aaaaaaccag gtttctttaa agggttaatg tcaaaaggtc ttaataatga
    12181 tgatgaagaa gatgaatatt ttgaagaaga aaatagtgat ggtgtagatg ataaaactat
    12241 aaaaatagtt ggatttaata aggcagaaga tgagtattta gaaatattag aaggaactca
    12301 aagtatgcca gagttagatg ttttaaaaga attacaaaaa gctaccaatg aaaatccagt
    12361 tgtagatact aaaccagaaa aaaaagttga tatagctaaa cctaatttaa atatagaaaa
    12421 aactcaacct atgagtattg tagcagagcc agttaatgag gattattcaa actataaaaa
    12481 gcctagcatt gagcttttaa ataaagtaaa taagaagtct gatgaaaatg gtaaaaagaa
    12541 agtgttgaaa aatgcttctc ttttagaaaa gacactatca gattttggag tggaagcaaa
    12601 aattaatcaa gttacagttg gacctactat aacaagatat gaaatacaac caagtccagg
    12661 agtcaaggta agtaaaattg taaatttaac tgatgatata gctttaagtt tagcagctaa
    12721 aagtataaga attgaagccc caattcctgg taaaagtgca attggaatag aagttccaaa
    12781 tgaagaagct caaatggttg gtgtgagaga agttctagaa agtgaagaat ttaataattt
    12841 taactctcct cttgcaatgg gacttggaaa agacgtagca ggaaaaatta taattggaga
    12901 tataggtaag atgccacact tactaatagc tggttctaca ggttcaggaa agagtgtgtg
    12961 tgtaaataca ttaataagta gtattttata taaggcaaat cctgatgaag taaaattact
    13021 attaatagac ccaaaagtag ttgaacttgc aaattataat ggaataccac atctattgat
    13081 accagtagtt actgacccta aaaaagctgc aaatgcttta aattgggcag ttacagagat
    13141 gaatagaagg tacaaattat ttgcagatgc tcaagtaaaa gatgtaacaa gttataatga
    13201 gaaagcggaa gaaaaacttc ctaaaatagt aataataata gatgagttag cagatttaat
    13261 gatggcaagt gcaaatgatg tagaagatta tatttgtaga ttagctcaaa tggcaagagc
    13321 tgctggaatg cacttgattg tagcaactca aagaccatct gttgacgtta taacaggggt
    13381 aataaaggct aatataccat ctagaatagc atttgcagta tcatctcaaa ctgattcaag
    13441 aacaatcctt gatatgggtg gtgcagagaa gcttctaggt aaaggtgata tgttattcta
    13501 tccacttggt gcagcaaaac cagttagact tcaaggggca ttcatatcag agagtgagtc
    13561 ggaaaaagta atcgattttg taaaaagtca ggttaaagat ggaataaaat atgaagaaga
    13621 tataattgaa actatatcta aggttaatac ttcaaagggt agtgatgagg atgagttttt
    13681 gagtgaagcg atagaatttg tcgtggaaag tggtcaagca tctgcctcta tgctacagag
    13741 aagatttaaa ataggattca atagagcagc tagacttata gattctatgg aagaaagagg
    13801 aataattgga gcaagtgagg gaagtaaacc gagaaaggta ttaataagca aacaggattt
    13861 gcagaattta gaaggtgaat agaattgtca gttataaaaa tagaaaaagc acttaagcta
    13921 gataaagtaa tatttgtaga tgtgagaact gaaggagaat atgaagaaga ccatatattg
    13981 aatgcaatca atatgcctct ttttaaaaat aatgaacata atgaagttgg aacaatttat
    14041 aagatgcagg gaaaacatga agcaatacaa aaaggatttg actatgtatc gtataaatta
    14101 aaggatatat atttacaagc agcagaactt gcattaaatt atgataatat tgtcatatat
    14161 tgtgcaagag gcggaatgag aagtggcagt atagtaaatt tattatcatc attaggtgta
    14221 aatgtatatc aacttgaagg tggatataag gcttatagaa attttgtttt agagtattta
    14281 aggcatgtaa tggatacaaa aaactttgta tctgttcatg gattgactgg tacaggaaag
    14341 actgatttgt tacatttatt agatgaaaaa ggaatagacg tgctggattt agaaggcata
    14401 gctaaaaaca gtggttctac ctttggtttt ataacttttg ataaaaagcc accatctcaa
    14461 aagaactttg aaacaaaact atttgaaagt atattttttt cgaaagagaa ttatatattt
    14521 gtcgagagtg aaagcaaacg agttggaagt gttacagttc caaatgaaat tttcgaggca
    14581 atgacacgag aaggacatca tatattatta gaatgtgata ttgaaaatag agttgataga
    14641 ctttgtagag attatattta tgataaagat gaaggtaata tattgatttt aaaagaatgt
    14701 ataaacaagt ttagaaaaag attgggtaat aaagtagtag atgattatat tgatttatta
    14761 gaatcaggtg aatataaaga acttgtaaaa agatatcttt tagaatacta cgacccactt
    14821 tatatgcatt cagtagagaa atataagtat agtaagatta taaattttaa tgatacacaa
    14881 aaagctttag aagatgttat agacttatat gagagtatat tggaaggaga aagtgaatgt
    14941 taaaaatagc attggaatca ttaggatgct caaaaaattt agtagatgca gaaataatga
    15001 tgggaatttt aaataacaaa ggctataaat taattggaga ttttgaagaa gctgatgtaa
    15061 ttatagtaaa tacatgtggg tttatagagt cagctaaaca agaatctata gatacgataa
    15121 taaactttgc agagttaaaa aaaactggca atttgaagtt gttgatagta acagggtgtc
    15181 tagcccaaag atattctgaa gaattaaaaa ctgaaattcc tgaaatagat gctatagtag
    15241 gaacaggaag ctatcaaaat atagataaaa tacttaaaga attaagtgaa atgcatcaaa
    15301 ttgtaagcct taatgatata gagtttgtat ttaatgaaga tttaccaaga tatatatcta
    15361 cacctagcta tatggcctat ttaaaaattg gagaaggatg ttccaataat tgtacttatt
    15421 gtataatacc aaaactaaga ggtaaatata gaagtagaaa atttgaagat ataattaaag
    15481 aagctaagaa attagctgaa tctggagtaa aagaacttgt ggttatagca caggatacga
    15541 caaagtatgg ttttgattta tatggaaaag aaagattatc agaactttta gaagaacttg
    15601 caaaaataga tggatttaag tggataaggg ttatgtattc atatccagaa tctataacag
    15661 aagaattgat acaagttata aagaaatatg ataatatatg tagttacttt gatatgccaa
    15721 tacagcatgc aagtaacaat attttaaaat taatgaatag aaaaactact aaagaagata
    15781 tattaaataa aatcaatctg ataagaagta atataccaga tgctatactt agaactacaa
    15841 taatagtagg gtttcctggt gaaacagaag atgacttcaa acaacttgtg gactttgttg
    15901 aagaggttaa atttgataga cttggtgcat ttgcatattc aagagaagaa gatacaccag
    15961 cagatagatt gccaaaccat atagatgaag aagtaaaaat acaaagaaga gatactttaa
    16021 tgatgattca acaaaaaata tctgaagaac ttaatgacaa aaagatagga aaaacttatg
    16081 aggtgttaat agaagaacag atagaagata atgtatatac aggaagaaca caaggtgatg
    16141 cagaagaaat tgacagtata gtgtatgtaa aaagtgtaga caatcttgaa gtaggagaat
    16201 ttgtaagtgt tcaaataaat gatgcaatgg aatacgattt aatgggagat gttttatatg
    16261 aacttgccta acaagttaac tttgtttaga atatttttaa taccagtatt tgttttaatt
    16321 atgttgctca atgtaccaaa taaattttta atagcttgta ttatttttat aatagcttca
    16381 attactgatg ctttagatgg aaaaatagct agaaaataca atctagtcac tgactttgga
    16441 aaatttatgg acccattagc agataagtta ttggttattt cagcacttac atgtatgata
    16501 gaagaccatc ttgtaagtag ttggatggta attataatag tggctagaga gcttacagtt
    16561 agcatattaa gagctatagc tgctgctgat ggaaaagtaa ttgctgctgg aaacagtgga
    16621 aaacttaaaa cgataactca aatggtatct atagtgtttt tattgttagg tgctcagttt
    16681 gaaaatgtat tgatattaaa tattggtgaa attctcattc ttatagctac actacttaca
    16741 ttatattctg gatgggaata tctatataaa aataaagagc tttttatgtc ttctaagtaa
    16801 aaaattatgc tttaataaat aaaaactaat gattaataaa taaaaaataa caacttaaaa
    16861 ttttaaaaat gtaaaaaagg gtatactatt atagtatacc tcttttcatt ttaagaatat
    16921 tttcttttgt gtatataatt attaataatg gtttataaat aaaatgtaat gaataaaaat
    16981 ataatcatta gtagcgtttt taaattgact aggtttgatt tatgttatat aattaatata
    17041 taacaagaga acaaatgttt gtagataaat gaagggatgg tatagagatg agtgtagatc
    17101 aagaaaaatt aaaagcgttg aatgaagctt taggtaaaat tgaaaaagat tttggtaaag
    17161 gttcagtaat gaaattggga gaagcaacat ctatgtctat agatgttata tcaacaggag
    17221 cgattggttt agacatagct attggtatag gaggtctacc tagagggaga atagttgaag
    17281 tatatggtcc agaatcttct ggtaaaacta ctgttgcgct tagttgtgta gcatcagctc
    17341 aaaaagatgg aggaatagct gcatttatag atgcagaaca tgcacttgac ccagtatatg
    17401 caaaagcttt gggtgtggat gttgataacc taataatatc tcaaccagat acaggtgaac
    17461 aggctttaga gatagcagag gcattgataa gaagtggagc gatagatata atagtaatag
    17521 actcagtagc agcattagtt ccaaaggctg aaatagatgg agatatgggt gattctcatg
    17581 taggtttaca agctagactt atgtcacaag cacttagaaa gttaactggt tcaattaaaa
    17641 aatcaaattg tgttgctata tttataaacc agttaagaga gaaagtagga ataatgtttg
    17701 gaaacccgga aactactact ggaggacgtg cactaaaatt ctattcatca gttagattgg
    17761 atgttagaaa aatagataca ataaaacaag gtgataaagt tataggtagt agaactagag
    17821 ttaaagttgt taaaaacaaa gtagcaccac catttaagca agctgaattt gatataatgt
    17881 atggagaagg aatttcaaaa attggagacc ttttagatat agctgctgat gtagatatag
    17941 ttaaaaaatc aggttcatgg tatagttaca atgatactaa acttggacaa ggaagagaaa
    18001 atgttaaaaa attcttggaa gataatttag atttaactac tgaaatagat gagaaagtta
    18061 gagcatttta caatttaaat gaagaacatg aagaatcagg tatttcagta tcaaaagaaa
    18121 ttgtagaaga ataagtaaaa atacaaaaaa ataactagta attaaagaca tgccacgctc
    18181 cctattagct tgacacaatg ttgaaaaaat tataaaatta agtgaggata aaatatctaa
    18241 atttaatttt aattattagg aatatttttt aatcatagtg atgacatttt gggattatta
    18301 acgaaggagg tggatgtcat agatagtgta gtaatgattg taataggtgc agctgttggt
    18361 attatagctg gatattttgt tagaaaaaat atatctgaag caaaaattgg acaagctgaa
    18421 aacttggcca aagaaataat agataaagca caccacgact cagaaacagt acaaaaagaa
    18481 aaattactag aagctaaaga agagatccat aagtggagaa cagaagctga aagagaaaac
    18541 agagaaagaa gaacagaagt acaaaagtat gaaaaaagag tagtacaaaa agaagaagtc
    18601 ttagatagaa aattacaaaa tttagaatct aaagaagtaa acctaagtga aaaattaaag
    18661 gtagtggaaa agaaagaaga agaagttgaa gtaataaaaa ctcaacagtt agaaaaatta
    18721 gaaagtatat caggaattac ttctgataag gccaaagaaa tcatcttaac caatgcggag
    18781 agagatgtaa gacgtgaaat gtctataatg ataaaagaga tagaaagtca agctaaagaa
    18841 gaagctgata agaaatcaag agaaattata ggatatgcaa ttcaaaaatg tgcagcagat
    18901 cacgtagccg aaactactgt aacagtagta agcttgccta atgatgaaat gaaaggtaga
    18961 ataataggta gggaaggtag aaatataagg actttagaaa ccttaacagg tatagacctt
    19021 ataatagatg acactccaga agccgtaatt ttatcaggat ttgatccaat aagaagagaa
    19081 attgcaagaa ttgctctaga aaaattaata gcagatggaa gaatacatcc agctagaatt
    19141 gaagaaatgg ttgaaaaggc gagaaaagaa gttgacaata ttataaaaga atatggtgaa
    19201 caagctgcat ttgaaactag tgtacatggg attcatccgg aattaataag attattaggt
    19261 agacttaact atagaactag ttatggacaa aatgtactta aacattctat agaagttgct
    19321 catatagctg gtataatggc tgctgaaata ggagcagata ttagattggc taagagggca
    19381 ggtttattac atgatatagg taaggctgta gaccatgaaa tggaaggtac acatgttgaa
    19441 ataggtatgg atttacttag acgttataaa gagtctaaag aagttataca tgccatgagt
    19501 actcatcatg gagattacga gcctcaaaca gtagaggctg tattagttac agcagcagat
    19561 gcaatatcag ctgctagacc tggtgcgaga agagaaactt tagaagcata tataaagaga
    19621 cttgaaaaat tagaagaaat agctaattca tatgaaggtg tagaaaaatc atttgctata
    19681 caagctggta gagaaataag aataatggta aaaccagaag ctataaatga tgaagaaata
    19741 catctattgg ctagagatat gactaagaaa atagaggatg aacttgaata tcctggacaa
    19801 ataaaagtaa gcataataag agaaacaaga gctatagagt atgcgaagta aaagaaataa
    19861 tatctaaata ataagaaaat atttttagaa atttaaattt gccacaagat atgataatat
    19921 atcttgtggc ttttaaattg tttaagttta attttatata atgcaaaaat aatctaagtg
    19981 ctaaaagtgc tacttacaaa agattaataa aataaagctt tatatatgta ttatttatat
    20041 aattatccaa gtttgtttga tataatgaag ttgtaaaatc aatactttac tacaaaataa
    20101 atagtaaata ctacagtaaa atctaaaaat aggatataat agtattaata taagaagatt
    20161 ataaataaaa cctgctaatg aaaatagatt atttttagta ggtttttaaa ttttttataa
    20221 taaatcttat ttttggctaa caagatttat tttttttaag actttactta ttattttaag
    20281 cattaattat gaaatttatc attttatta
//
LOCUS       DAGQVA010000075        20276 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.075, whole genome shotgun sequence.
ACCESSION   DAGQVA010000075 DAGQVA010000000
VERSION     DAGQVA010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20276
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.075"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(83..961)
                     /locus_tag="MIV85_002962"
     CDS             complement(83..961)
                     /locus_tag="MIV85_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBY2962288.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            complement(978..1295)
                     /gene="trxA"
                     /locus_tag="MIV85_002963"
     CDS             complement(978..1295)
                     /gene="trxA"
                     /locus_tag="MIV85_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBY2962289.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            complement(1445..2677)
                     /locus_tag="MIV85_002964"
     CDS             complement(1445..2677)
                     /locus_tag="MIV85_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2962290.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(2667..3338)
                     /locus_tag="MIV85_002965"
     CDS             complement(2667..3338)
                     /locus_tag="MIV85_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962291.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(3354..4190)
                     /locus_tag="MIV85_002966"
     CDS             complement(3354..4190)
                     /locus_tag="MIV85_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962292.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(4216..4890)
                     /locus_tag="MIV85_002967"
     CDS             complement(4216..4890)
                     /locus_tag="MIV85_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBY2962293.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYIFKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(4904..5632)
                     /locus_tag="MIV85_002968"
     CDS             complement(4904..5632)
                     /locus_tag="MIV85_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBY2962294.1"
                     /translation="MMFDRVKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(5759..6448)
                     /locus_tag="MIV85_002969"
     CDS             complement(5759..6448)
                     /locus_tag="MIV85_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962295.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(6456..7019)
                     /locus_tag="MIV85_002970"
     CDS             complement(6456..7019)
                     /locus_tag="MIV85_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBY2962296.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(7021..7989)
                     /locus_tag="MIV85_002971"
     CDS             complement(7021..7989)
                     /locus_tag="MIV85_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBY2962297.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     regulatory      complement(8090..8133)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            8498..9127
                     /locus_tag="MIV85_002972"
     CDS             8498..9127
                     /locus_tag="MIV85_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2962298.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMYSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            9102..9506
                     /locus_tag="MIV85_002973"
     CDS             9102..9506
                     /locus_tag="MIV85_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBY2962299.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            9509..9982
                     /locus_tag="MIV85_002974"
     CDS             9509..9982
                     /locus_tag="MIV85_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBY2962300.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            10552..11217
                     /locus_tag="MIV85_002975"
     CDS             10552..11217
                     /locus_tag="MIV85_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBY2962301.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            11239..12171
                     /locus_tag="MIV85_002976"
     CDS             11239..12171
                     /locus_tag="MIV85_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBY2962302.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            12192..12833
                     /gene="pcp"
                     /locus_tag="MIV85_002977"
     CDS             12192..12833
                     /gene="pcp"
                     /locus_tag="MIV85_002977"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBY2962303.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(12953..13285)
                     /locus_tag="MIV85_002978"
     CDS             complement(12953..13285)
                     /locus_tag="MIV85_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962304.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            13551..14171
                     /locus_tag="MIV85_002979"
     CDS             13551..14171
                     /locus_tag="MIV85_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2962305.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNKLIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(14496..15320)
                     /locus_tag="MIV85_002980"
     CDS             complement(14496..15320)
                     /locus_tag="MIV85_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBY2962306.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(15331..16734)
                     /locus_tag="MIV85_002981"
     CDS             complement(15331..16734)
                     /locus_tag="MIV85_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2962307.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(16738..17463)
                     /locus_tag="MIV85_002982"
     CDS             complement(16738..17463)
                     /locus_tag="MIV85_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962308.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLFAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(17575..18348)
                     /locus_tag="MIV85_002983"
     CDS             complement(17575..18348)
                     /locus_tag="MIV85_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962309.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(18354..19241)
                     /locus_tag="MIV85_002984"
     CDS             complement(18354..19241)
                     /locus_tag="MIV85_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962310.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRAGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(19255..20235)
                     /locus_tag="MIV85_002985"
     CDS             complement(19255..20235)
                     /locus_tag="MIV85_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962311.1"
                     /translation="MFISLGILVLILMISIFITPVLETESYYIDKEKGRIEDTRSGID
                     IGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNEYKDISFWKVFNYRV
                     TNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALNSKIFVALLVPLVIY
                     SVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKYVILNIGIELLMFEG
                     WAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLSVVSNVNYYDLIFGF
                     NKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIKSDYISR"
BASE COUNT         7021 a         3226 c         2176 g         7853 t
ORIGIN      
        1 aataaaaaac tgtcttgaaa taataaaatt atttcaagac agttttttat aaatatcttt
       61 aaaaagttaa tcaatataaa tattaagccc tctttaattt atctaaatag taaacagcat
      121 ttaaagctgc tatttgccct tgaccagctg cttttatata agaatatggt tttccaacac
      181 aatctccagc agcaaagcat ccatctatac tagtcttcat attattgtca actttaatat
      241 gaatgccatc aatctctatt ccaggaacca atgcacttgg agctgtacta tcttttataa
      301 cgaatactcc atcaacttca atgtggtttt ctttaaaaga tactttgttt acaagtttat
      361 ctccatctat ctgtactggt ctgtcatgta taacttcaat agaatcatct aggttatctg
      421 aacttctcat aagattatct tttttgtaca taggtataaa ataagtcttt gaagtgagtt
      481 cacttaaaaa atttgcttct tctttagatt cttcattata tcctataact gctacctttt
      541 tatttctata aagtggtgca tcacatgtag cacagtagcc cacacctctt cctagaaatt
      601 cttcttcacc cttgattggt ctagtatact ctaccccagt tgcaaggatt acagtagtag
      661 cttcatacat atcatttcca gacattattg taaagtattc tcccatagca taaatattat
      721 ttattctttt attttcaatt gaaatatcca tactatctat atgtgattta aacttgtctt
      781 ttaattcatc accacttata tcataaaaac ctaaataatt atctattgaa ggagctttaa
      841 caagcttatt acttaaatta tcattaccaa acatgataat tgttttattt cttatttttg
      901 catttatagc agcagacaat ccagctggac cactgccgat tatagctata tcatatctca
      961 taatactcac ccatttttta taaatatgat tttacttgca tttcaatttt gttctttggc
     1021 atgaatccaa ttaaagtttc tactggtttt ccatctttaa atataatcat agttggtact
     1081 gtagatacat tgaattgttg agctatttct aagctctcat ctatatcaac ttttacaaat
     1141 ctagctttat ccttcatctc ttcacctaat tctgcaaata caggtcccaa catgttacaa
     1201 ggtccacacc aagttgcaaa gaaatcaact acaactactc ccttactacc ttcaacacta
     1261 cttctaaatt cagatgtatt tataactttt gccattttta aatcctccta ttaaacttta
     1321 ttatccctat ataattatac tatgaaattt ataaatataa atttactttt ataaggtctt
     1381 tttatatttt atactaatta gtatacccat tcttcatttc taaaaacaat tttttatatt
     1441 tttattattt taactttttg ggtattgaca attcaaatgt agttccaata tctacatcag
     1501 aagttacatt tatatcaata gataagttta aactaatcat gcgagctatt gaaagtccta
     1561 ttccagaacc ttctaaatct ttatttctta cattttcact tctaaaaaat ctatcaaata
     1621 taagaggtat ctcttctttt tttatgccta taccagtgtc acttataagt aaagttacct
     1681 catcctctat atcttctttc aattctaatg ctatctcatc acccaatttt gtatacttaa
     1741 aggcattatc aatgaaaatt aatataagct gtcttaattt atttttatct gttattataa
     1801 ctttattctt aagtttagaa ttaaacacga atcttttttc ctgaaactca gcaatgtcaa
     1861 tatagtcttc tgatatttct tccaataact tttctaaatc tatttcttct aaattaactt
     1921 taacaataga gtcctcttta gtaagagaca ataaatcagt tatcattttt ttaagtcttc
     1981 tagtttcctt cattgcagta gctattgttt caacttcatc atttactgta ctttctgggg
     2041 attttaacat actttctaat tttgatgaaa ctattgttat tggtgttctt aattcatgag
     2101 aagcatcttg tataaactta gcttgatttt tccatgctgt ttctattgga attaaagctt
     2161 ttctagtgag atatacagcc acaaagtaag taattattac agaaattaat attccaatta
     2221 taagaacaga tgtaagctgt cttaaagaat tcatctcaga atctatattt ctaattatct
     2281 gtatttggta tctacctaca tctacattta attctctaaa agtatatcca ttttctgtgt
     2341 atttaaaaaa cgaatttttt ttatctagtc ttctatctgg aagtaactca tcaaaatatt
     2401 cattttgagt atagtaactt atccttccat cttcatacac atacaccata tctttaggat
     2461 ctttcagtct tattgggttc aaaaatgaag ttcttttaaa ttgagagact atatattcaa
     2521 gttcatcatt tatctcacta tcaattccac tatatgtaag tcccctaaaa tatgagtata
     2581 taaatataga aaagattatt aaaaaactac ctactacaat aatatacatt tttattaaat
     2641 gatttttagt actggtaaat acattcttat ttatcatcga atatatatcc taccttacgt
     2701 ttagttttaa tatatttatc atatccatat ttacttagtt tttttcttag attacttaca
     2761 tatacttcca ctatttcaat agtcgcatct gaatcaattc cccatattct atcataaatc
     2821 tgctctttta ataaaattga acctttattt aatacaaaat actcaagcaa gttaaactgt
     2881 ttgttttgaa gttttatttc ttctttttca atatacactc ttttttctag tgtatctaaa
     2941 tataaagatt taaattctaa tccgtttctt tcttttatct ttccattagt ccttaatata
     3001 gcgtataccc tagctactaa ctcttccata taaaaaggtt ttgtcaaata atcattagct
     3061 cctatagtaa atgcttctac tttgtcatct aatgtttctt ttgctgtcaa tataagtaca
     3121 ggtgtatcta tattattaac tctcattttc tttaggatat caaatccatt tatattagga
     3181 agcattaagt ctaaaatgac taaatcatat atattttgat ttactaagta taaagcttct
     3241 tctccatctt cacacttttc agtttcaaaa tgcttgctaa gttcttctac tacactttct
     3301 aaaagtatct tattatcttc aactattaaa accttcataa gtatccccta cctttatttg
     3361 tctatcttaa ctttatgaga ttttaagtca atatccacat tggctttttc ttttatatca
     3421 tcatacgtat atcccactat ttcaacactt tttgcctttg ttgaacacaa tatatctata
     3481 tctgtctctt ctgaaggctt taaaatctta tatgatggca cacgatttac tgttaaatat
     3541 tctccatttt cattaacttc tgctgtctta agaataatat ttcctaaatc ttttgatgat
     3601 gaatttttta cttttacttg atacgtaatt ccctcatttg attcatttac ttttttaagt
     3661 tctgatgtag atagcacctc atactgacta ctattttcta gcttaatatt attatttctt
     3721 atattaatag tattttcttt taaattaaca tacacaatct taccctctgc ctcatattca
     3781 tatgcataaa cttctacacc ctttacaaaa gttttatgcc cacattctat gtaagcaact
     3841 ttcccaggca ttaaagtcat gtccaacaaa gccttactat ccgaagatat aattttttta
     3901 ttctcatcat attcattata tatcaattca acattggata tattaaatgt tgaattattt
     3961 tctacctttg ttgatgtatc tactttatca ccttcatcta tatttataat ttctgatttt
     4021 cctatattca atacttttgc atttccctca tctattttta tctcattttt atcttctgtt
     4081 tgaatatcaa ctgaatcagg ctgttcatct ttttcacatg ctgtcaacat aaaaataaat
     4141 attgttaata taatcattag agaaattgat ttttttacta ttttattcat attaagcacc
     4201 tcatatagta gtattttata gtagattttt atactttttc ataaattctt tcaatgcctg
     4261 tgtaagtatt tgatgttttt caaaattcga attactacat aatctttcaa aatcattcca
     4321 tatttcttta tctatacgta ttcttgttgt ttttaattca tctatgtgtt catcatctat
     4381 atgtacatct tttttattag atactttttt aggctttata ttgtaatctt ttacttctaa
     4441 ataccaatca tatacttcac aaagcttatc taaatcttct tgagttatat ttatttttct
     4501 atctttctta ggcttaatat tttgttttgg ctttgcattt tttaaacctg tatcattaaa
     4561 ctcaatttgt tcaacacttt tacttaaagc cttttcatta gaaatctttt ttttggtgct
     4621 tacttttttt ctattactta tagtattctt tttacttttt tcatactcct tagctttctc
     4681 ttcttccaag tttctattat ccaaactttt attataattt aattcgtctt taaatatgta
     4741 tttacctttt tctgacttat atcctttttt atttaaaaaa gttcttaaag tactttgact
     4801 aatctttaga ttttgagcta tctctgcaaa tttaaatcct ttgctttgaa gttctaaaaa
     4861 tttgtcaatt ctgtcttcat tgttattcat taatattcct ccgtcaacat cttcttgtct
     4921 ttcttttcat acttcttatt atattcttct tttctaaatc tactctattt gattcaatta
     4981 ttttttgtag cattttatta taagtgaaat catctaaatt attatttttt atatagagaa
     5041 aagtttcctc ttcacattta ataaaacaaa ttgatagcaa ccatgccata cccattttaa
     5101 cataatattc ttcactttgt atattattac agtattcaaa tatttcttta atatgtttat
     5161 catcaacata atatattaaa aacataacta atgcaaatct aatttcccat ggattctttg
     5221 aataaacata ttttttaagt atatcataca tattttcttt atattttttc atagacttta
     5281 aatcagaaca aaatccatcg caaactgacc aattatcgat tttaggtata aatcttttta
     5341 catagtataa agtttcttca aaattactat ttatattgcc aattaccata ccttgtagcc
     5401 taacttcttc atagtatgta tcctctgcta cttctaaaaa ttccttccaa ttcccttggc
     5461 ttatttcttt tgataacttt cttaaattag gaactctaat acctattata ttttctgttc
     5521 caggtataag ctttttatta aaatctctat attttatatc ttgtatagac atcatatatt
     5581 ctaaaagttc attataatcc aatttattcc attttaccct atcaaacatc atttaattgc
     5641 tccttaattc cttttttctt attgtaacat aaaactctac aaaaaaagct tctaactatt
     5701 agaagctttt tcaaaaacat aagaaacttt tcaattttaa atttaaacta aattaatgct
     5761 aatctcctac accaaaatct gtattattgt ataaaacttc tatatttgga ttttcatcca
     5821 agaatttata cttactaaca aaccatttca ctaactcttc atctcttttt atactagaag
     5881 aattatttat aaaaacattc actgtcgctt tttcaaaagt atttaggata atctctatat
     5941 ctttatctat catctctttt gtttgtcctt ttattccaac cataatacaa ggtgaatcaa
     6001 aatattcttt tacatcttgt ggagtcttaa aatttgcatt tttatttaaa atattatttc
     6061 taaaatcatt gtcaaaggtt tcaactccaa ttttaaatac cacaggaatt tcaaaatact
     6121 ctctcatttc cttaagccta tttttgtaag accaatgact ttctaaaaat aattttttta
     6181 tatttttctc ttttataata cactttattt tttctaaagt atccttaggt aattcaaaac
     6241 agcttccaga atttatgact tcaagaactc catatttccc agttacgttt tttaaaacct
     6301 ttagatttaa tttattcatc tcttcttcta aattagaatt atcatctata taatcacaaa
     6361 aagaacactt tccccatata caaggaaatc ctttaagcag aacaatttct ctttgatttt
     6421 tatttgttat ctcactatat ctatccattt tctatctatt ttcctccagt caatgatacc
     6481 tttaaagttt ttggaactgc atttaatcct aaattcacta aaacaactgc taacagctta
     6541 tctccataat cagtaaatac ttgggttaca aacacactaa aaacatcccc cagtcctaac
     6601 actttcaaga tttgcactat atatgatgaa cctgaagagg tcatacctcc aaataaaaat
     6661 gctgaaatta ttgaacttat tatagatgtt ggaatggcaa ataaaagtac tcctagtgga
     6721 gtttttaaac cccttaaaaa attcttttta aatgctattc cagcaagtaa tccggttgat
     6781 atttgaactg gtgcaaaata gagagaatac acatcaaacg taattccact tattaaactt
     6841 ccaaacacac ctgtaacaac agcgtattta ggtcctaaaa gtgaagctat cattatagtt
     6901 cctattgaat ctaagtatac aggtaatctt aatcccatag ctataaaagc gcctattata
     6961 tttatagaaa taccaaaagc tataagtgta atagttttta cacatatttt tcttttcaca
     7021 ctatatcact ccttccacag agtctataat gtcttcataa cctttaaaaa gcctctttaa
     7081 aaacatgtac ataaatttct tctcatcaac ttcatttaga acaattgcat taggattttt
     7141 tttatagaaa ttgaaagaat ccactataga ctgacccata gctattccat cttctacaac
     7201 ttctacatat gattcaaatc ctttacatat acttctatct ataaagtacg ctactgctag
     7261 agggtcattt atcacacagc caattattcc ctcctgttcc caatggaaat caatataaaa
     7321 tctagttatt tcagttatat actttgccat cttcttatca agtctattta taaactcaat
     7381 aatattagga gtaagtacaa tttttctagt tacatctaaa cctaccatgt ggattttttt
     7441 agataaattc ttgtaaacat aatctgctcc atgtgggtct acccaataat taaactctgc
     7501 tactggagag caatttccat gaatcctaaa tgctcctccc atagatacaa actcatcgag
     7561 attttcaaat gctttcttat ctttaataag tgctttagct atatttgtaa gtggtgcaag
     7621 tgctattatt gatacttttt catgattata taaagtattt attataaaat ccactgctcc
     7681 attttttgct ttagctccta caaccttttg ataaaagttt tctccaatac catcttctcc
     7741 atgtgtatct tgagctgtta caagttttct ttttagtggt gcttcttctc ctatatatac
     7801 tggaatattt agtgaagaac acatttgaag tgtttttagt gcattttctg cacctatatt
     7861 tgctggaaca tttccacaac atgtggtaat tccaattact tctagctctg gtgagtttaa
     7921 agccagaaga attgccaaag aatcatcaat tcctgggtca caatcaatta ttacttttct
     7981 cttttccatt ttttatcctc cttgatttgt ggtcgaggag aactacacat cttttttcca
     8041 ctttcaaaaa ggtgtgtcta agggtattaa ttatatactg ccactatata attccttagt
     8101 tttttatact tggagttctc gaacaagtac agatgtaaaa tcatattttt aggctactta
     8161 ctatagactc ttaaaaacta tagactgtta aaaaattttt aaacatctga tttaatagct
     8221 ataaaataaa ttttatagca taaaagaatt tattatattt taatgtatct tattaaagtt
     8281 tatttagaat tatgaaccaa ctttaataag atgtggcgca tttaaaccga ttattattat
     8341 acaataatat cttaaatatt acaattaata acattaattt attatccata aaaatatatt
     8401 aacttatatt atttaataat ttattgacag tattaaaatt aaattataca ataacagtgt
     8461 aaattaactt aacaccgtta agcaaagagg tgattatatg agtatcaaag aaagacgtaa
     8521 aaatgaaaaa gaagaaatga agaaaaagat tatggatgct agcatcgaaa ttataaacca
     8581 acatggatat gaaaatttat caataagaaa aattgctaca aaaatagaat attctccaac
     8641 tacaatttat ctttactaca aagacaaagc agagattatc agcgatatga ccaataaact
     8701 ttataacaca gtagaaagta atgccattga cattatgaat aattgctcat cactaccaat
     8761 agataaacaa atcatagaaa ttatgactag ctttataaaa actctttcta gtgaaccaga
     8821 gatggcaaaa tctatcatgt atagtagaat gaatattata tttgcatctg aaaatacaaa
     8881 caatacgcct agcaataatg gtataaaaat gcttgataaa ttcctttcca ttggaattga
     8941 acaaggaata ttcaaaaaaa atatagataa aagctcatgg atgcttataa gtgcattgtt
     9001 aggattcgtt ttatgtgttg ttgaaaataa actatattct ttacataatt tttctcaact
     9061 tatagaaaat ttcttagata ttttagtggg aggactttac aatgaaaatt cgcaacaagg
     9121 ctactaataa aaagaaaaaa tatgtaaaaa tatctattgc tctattcttt gtatttatat
     9181 gcattattat tgtaattgta agcaacttaa agccagaaaa cttggtagta aaagatatag
     9241 atattaataa tgttaaaaat ggcatttata ctggaagtgc tgataataac ttggtaaaag
     9301 ctactgtgtc tgttgaagtt aataatggta aaatccaaaa tattaatatc ttaaaacacg
     9361 accatctttt aggtaaacct gctgaaaaaa ttacaacaag tattattaaa caacagtctt
     9421 tagatgtgga tgctataact tctgcaactt atagcagtaa tactatacga aaagctgtag
     9481 aaaatgcttt aagaaaggga gaataattat gaatactatt attatatatt caagtaaata
     9541 tggttgtaca aaagactgtg caaatatact aaaaaataaa ctatcagata atgtcactat
     9601 tgttgatatt aataataata ataaaattga gttatcaaaa tttgataaaa ttattattgg
     9661 aagttctata tatgttggtt cagtttcaaa aaaaatacaa gtgctatgta atgataatgt
     9721 agagttatta aacaaaaaac aagttggcat tttcctttgc tgtggctttt ctgaacaagc
     9781 agataaatat ttaaaatcaa attttccatc atccttatta gaaagtgcaa atgctattgg
     9841 aatttttggt agtgaagctc gattagaaaa aatgaaattt ttagataaac ttattatgaa
     9901 ggctgtttca aaaggtaatt atgacagttt tagaatatca caggataata tagataattt
     9961 tttaataaat cttaatagct aaaataaaac taattatttc tatgataaat tcttttattt
    10021 ataagtaata ttgctcaaaa tagtctttaa actttatcaa aattttattt ttcttagtga
    10081 aatctaatga aactagcact taatatatgc tttattaatc ataacaaata tgttttatta
    10141 atcataacaa aaagagagtg tctaatgaac taaaaaattc attagacact ctctttttgt
    10201 atgaaatcaa atatattttt atcatttcaa aagtgaaaaa tacacttgtc tctatgtttg
    10261 gcacattctc tttttataat ataatatcta atttaaaacc tatttcaaat attgacatat
    10321 acttaaacta tagacttaca aaatcaattc atattagctt aaaatataat ctttgttatt
    10381 caaattccta tacacaacca ttatttactt tgatacttta aaacatcttc cctatttttt
    10441 attaaatttt ataataatag tcctattaac gcaaatacta taaaaagagt ttaactttat
    10501 ccattaaata aatttaaatt aaaacatata gaaatggaag gagaacaatt tatgataaaa
    10561 ctaatcggta tattgatagt tgtaattgga tttatactta aaattgacac attatttact
    10621 gtattattag caggagtggc aacaggaatt gttgcaggat tagattttaa tcaaattttt
    10681 acaattttag gagattcttt tgtctcaaac agaggtgtat cattattcat attaacattg
    10741 ccagtaatcg gtgtattaga aagatatggt ttaaaacaaa gagctgtttc tttaatagaa
    10801 aaattaaaaa gacttacaac aggaaaagta cttactatat acatgatagc tagacaaata
    10861 gctggtgctc tatcaataag aatgagtgga catcctcaat ttgtaagacc acttgttaat
    10921 cctatggcac aagctgctgg tttaagtaat agtgatgaac taaaagaatc ggatgaagaa
    10981 gccataaagg cattatctgc tgcatcagaa aactatggaa atttttatgg tcaaaactta
    11041 tttgcaggta gtagtggagt attacttata gcatctactc tgactcaatt tggatacaat
    11101 gtaactggac ttaatatcgt aaaggctagt actattatgg cagtaatagc acttgtagtg
    11161 gctacaatcc agtttacctt atatgataaa aaattaaaca aaagtcataa aaaatagttt
    11221 tatttaggag gaataaaaat gcaaaatttt ataaacatat cattagaaat cttttacgca
    11281 ctaatgggat ttttaatgat tgttatagca tataagtctt ttactaccat aaataacaat
    11341 aagaaatatg gtacatcatt attttggata cttatatcac tgccattcat atttggtaga
    11401 ttgattccag ccaatataat aggaataata ttaatattat ctagtttatt aacactttct
    11461 aaacaagttg tatttgcaaa gtatgaagaa ccagatgaaa attttggaaa agaacaagca
    11521 gacaaactta aaaataaaat atttatacca tcattaatat tagcatttgc tgcagtagta
    11581 gtagctatga gcctttctaa ttttgataat tcttctcaat ttgcaatagg tgtgggttca
    11641 ataattgcat taatatcagc ccttataata actaaggcaa aacctgctac atcagttcaa
    11701 gatggctcaa gattacttca acaaatggga cctgctagta tgttaccaca acttttagtt
    11761 gcattgggag ctttatttac tcaagccgga gtcggtgaag ttatttcaac catgatatct
    11821 ggtgtagtcc ctgctgatag cagattattt ggtgttatag cttatgtatt aggtatggtt
    11881 atatttacca tgataatggg aaatgcattt gccgcatttt cagtcataac ggcaggaatt
    11941 ggtattcctt ttgtattgtc tcaaggtgga aatcctgcta taattggagc attagcatta
    12001 acagcaggat attgtggaac tctacttact ccaatggctg ctaattttaa tatagttcca
    12061 gcagccttgc tagaatgtaa aaatgattat attgttataa aatatcaagc tccagttgct
    12121 ttggtattaa ttatagccca catattagta atgtactttt taggatttta atataattag
    12181 gaggtaaaat aatgaaaatt ttgttaacag gatttgaccc atttggtgga gaaccaataa
    12241 acccagctca agaagcagtt gaaagggtca ataataatat aaacggtgca gaaatcataa
    12301 agataactat accaacagtt atgacaaaat ctgttgaagc tatagataaa gctattcaag
    12361 agcacaatcc agatatagta atatcagttg gacaagctgg aggtagattt gacattacac
    12421 ctgagagagt tgctataaat atagatgatt ttagaataaa agataatgag ggtaaccagg
    12481 ttatagatac tattataaaa gaagatggtg aacctgcata tttttcaaaa ttgcctgtaa
    12541 aagctatggt aaaacatatg aatgaaaata aaattccagc tagtgtttca aacactgcag
    12601 gaacatttgt ttgcaatcat gtgatgtatg gaattcttta tatgatagac aagaaatatc
    12661 ctaatataag gggtggattt atacacatcc catatacaac ttcacaagta atagataaaa
    12721 aaaatacacc attcatgtct ttagaagaaa tagtaaaagg cttagaatta gctatagaag
    12781 cttgtattat atataaagaa gatgtaaaag aaattggtgg tgaaatttca taataaattt
    12841 tttagtattt ttataaatta aaaatactaa ctattaattt aaatatagac tgtgagtaga
    12901 ttattcaaac aattttactc acagtctttt tatggtatct acagatacaa aattaaggtc
    12961 tattcctctc tccccactca cacattgcat ctaaaattgg aatcagagat tttccccttt
    13021 ctgatagact atattctacc ttaggaggta tttgaggata ttcagtacga ataatcaagt
    13081 tatctgcttc taattctttt aatgataaac tcaaagtttt ataggagata gtatttatat
    13141 aacgttttaa tgcattatat cttacaactt caaattctac aagacagtaa agaattatca
    13201 tcttatattt accactaatc agtgaaagtg tataactaaa tcctgtttca cttaaatctg
    13261 tatttgatat acagtctata ctcatatatt acactctcct tttggttagt attgaacaaa
    13321 aatgtgcgta cttgttttta gaataattta taataaaatt atagtgtaag aataattgaa
    13381 agtcaatttt ataataggag gtgtatttac taaaaaaaaa gttattttaa ataggattct
    13441 aagattagac atttctatat aaattgataa tattcatgaa aatcctattt tataaaaaat
    13501 aatatctctt agaaaatcta ttaaataaaa ttcattggag gaaatttata atgaaagttt
    13561 tattgataaa cggtagccca aaccaatatg gatgtactta tacagcacta aatgagatta
    13621 ctaaagtatt gagtaaacac gatattaaaa cagaaatact gtatttaggt aaagaaacaa
    13681 tcccaggatg tattagttgc gcatcctgtt ttgaaactgg aaaatgtatt cgaaatgata
    13741 aagttaataa attgattgaa gatctggata atattgatgg tattattatt ggttctcctg
    13801 tttacttttc tagtgcaact ggtcaattaa cttcttttct tgaccgtcta tttttcatag
    13861 ctggaagtcg catggctaca aaattaggtg cttcagttgt gtcatgtaga cgtggtggtg
    13921 caagtgcaac atttgaccaa ctaaataaat atttttcaat cagcaatatg cctattgtat
    13981 catcacagta ttggaaccag gtacatggct ttactccaga ggatgttatg aaggatgaag
    14041 aaggattaca gactatgcga actctaggag aaaacatggc atggcttctt aagtgtatat
    14101 cagcaggtaa aaaagctgga attaaagaac cacaatatga agaaacaatt atgactaatt
    14161 ttataaaata aataaaaaat gtactaatat taattaaaac aaaacactaa tttataaata
    14221 aaataagcat aaatgtagga taaaaagcac taaaacagag gtattgaatt ttatatcaaa
    14281 cctctgtttt attattacat taataaccaa accatgtata acatcatata tttctaaata
    14341 aattataata ttatattcta atgttattga aattacaata actgaatttc tgctcataaa
    14401 tttaaatatt ctacaaatct catctaaata acaattttaa tagacctaaa acaatcctca
    14461 tactgttcat tttgtattaa aaatatcact tacaatcaaa aaccatttat taagtatatt
    14521 cctaagatat acaatatata tacatggatt ggatagtata aataaaataa atacttcata
    14581 ctcttccctt tttctccatt gtaaagtaac attaaaggta gagaagcaat catcatccat
    14641 tggtaatttt gtaaaataga attttttaaa ctataatctc catttgacat tgttgtaaat
    14701 ataaatatac acattaaaac ataacaaata ctcaaactga actttttacc tctacacaaa
    14761 taaaaaataa tcccaagtat aatccaaatt ggtccacctt ctactaaaaa tggtactggt
    14821 accaaaatca taaataaagc aataactctg ttagtgactt taaaaagtaa agctactgta
    14881 aatattccta aaattatagg aatgattatc atcaataatc ctataataaa atatttaatt
    14941 tctttctctt ttctaaattt ctttatgaac tctattgctt gtaaataaat cgctattaaa
    15001 aataatgttg aaaaaatgtt atttataatt atagctcctt ctggatgtga aaatacatta
    15061 ttaattattt gatttcctat agccataata acagaccaaa tatacaatct acttatatat
    15121 ttttttctgt tactagtgtg ataaaatcct tcaacagcca tgaatataaa cagtggtgct
    15181 gatattctgc ctacccaatg aaaccaaatt ggtatttgca ttgtttgtgg cataaatgct
    15241 gctatatggt caaatgtcat aaatattaat gctaaaattt taatagtaaa cccacttata
    15301 ccttttttaa aaaaatccat atcatatctc ctaattttgt tttatctcta taataatttt
    15361 tgttcctatt ccaatttcac tacttacata aattttacct ttatgaatct ctattatttc
    15421 tttagaaata gccataccaa gacctgaacc tttatgcatc tcacctgtat tagtacctct
    15481 ataatatttt ttaaaaatat gtttcaaatc acttttgctt attccaattc cattatcttt
    15541 tattataatt tctatattat ctttttttac aatttctaca cttatcaaag ttccttcgct
    15601 attatgaact attgaattaa atataagatt ggttatagcc cttctgaata agattgaatc
    15661 tacatatact tcaattaaat cttcattact ttcaaattca atattcctat ttttatatct
    15721 attatcattt aaaatatcaa ttattatatc tctgactaaa ctgactaaat ttattttttt
    15781 cttgtccaga actatagtat tattttttaa tcgagtagat aaatttaaat catcaactaa
    15841 atcttttata tacttagact tattatatat aatttctgta tactcttgta tttcatcttc
    15901 ttcaaactca taatctttgt cattaattat ctctgcatac ccttgtatag atgctagagg
    15961 tgtctttata tcatgtgtta tatttgccag ccattcctct ctcaactctt cattttcttt
    16021 tctctcaact tcatttactc ttaaagtatc agctaacata tttatatttt taaaaacttc
    16081 ttcatatata cctctgtcct taagatataa actataattt ccattagcca tagtctcaat
    16141 actccatagt acgcttgaaa ttggttttgt aagttttcta ctaaataaat atcctacacc
    16201 taaagctacc acgctatcaa ttactagtgt tataatgata actttattta aagttttttt
    16261 aatgttattt tgagaatagg ttaaaattat tcttgatata tctctactag gtatacctac
    16321 tattatgttt aaatgttttt tgtttaaata tttttctagt acaaaattaa catactttgt
    16381 ttctatatac ttgtaattat tcaccatttg aaagggtgta tatttttttg gagtatcctt
    16441 tggcacattt actccataaa cttcctctcc taaatcattt aaaacctgta tccaggaatt
    16501 tgatttttct aatttttcag ctccaatctt agatagttta aattctccat ctttttcata
    16561 taaatctttt tcaaaagaac gtgcaaattc ttcaggatta tttccagaat ctacaacttt
    16621 aaaaaagcta ttagttgaaa tcacatacaa tatagatatg atatttataa ttactactga
    16681 tatagctaca aacacaattg taaatataaa atttctagta atcttccact tcatattcta
    16741 atcttccttt actgctaatt tatatccaag accttttatt gtcagaatat attcaggttt
    16801 tgaaggatta tcctctaatt tttccctaat ttttcttata tgaaccatta tagtattgtc
    16861 aaatccaaca taatcttctc cccacacttt atcccatagt ttttctttac ttataatttg
    16921 attttgatta tgtgcaaata aagataggat ttttagttcc tttgcaaaca gtcctataga
    16981 ttttccatct tttataagtt ctgccctact ttcatttaat atatatgggc caaatgatat
    17041 aattttttct tcattattat ttagattttt actttcgttt tgagcatcac taaaataact
    17101 taatcttctc aaatgcgctt taactctaaa agccacttcc ttagggctaa aaggttttgt
    17161 aacataatca tctcctccaa tcgctagtcc aagtaactta tctaattctt cggttttagc
    17221 tgataaaaat attattggag aattggaggt ttttcttatt tctttacaaa tatcataacc
    17281 ttcgccatct ggtaacataa tatccaatac aatcaaatca ggattaatac ttttaaataa
    17341 ttctaatcct tcttttttag tttttgcagt atatatatta ttaaggcctt ctttttttag
    17401 gacagtttct aaaagcttca atatttctac ttcatcatct attattaaaa cacgattttc
    17461 cataaacaac ctcctgtaat aatttacata tatattagca tatattttat ctaaaattca
    17521 tttatcttat ttttaattaa actaaaatat aaataaaatt actattattt ttagttaaaa
    17581 ccttttgctt gatgtaaaat tttcatatgt tattttagtt aacactatca ttaatataat
    17641 tgagattact atagaaaaaa ctatcaaaat acttggtaca ttatacttaa ccatttgttg
    17701 gctcatcata atccaatttg gagtcactga cataaatttt atagctttat ctggtataaa
    17761 acctacacta aagtatggaa ttgccattat caatccacct agtataaatg gaattacagc
    17821 cgatttaaat atagatgaaa gtgttaagcc tatttgtgca aatataaaag aagcaaaaat
    17881 agtagtcaat ataacaatta tatacatttg tattactgta agatttaaat tactatttcc
    17941 aaagtaccat aagttatgaa tcgattcatt taaattttta aaatcaaaaa aactaaaacc
    18001 tctaattcct actaacaata taaaagaaat attaataata gataaaatta atccattagc
    18061 tactagtttt gataatacta ctgatttttt tcccttttta gttgtattta ttaaacctgt
    18121 catattagaa tcatattctt taatgtaatt tccagaagtt attataaaca ttatcaaacc
    18181 tattagaggt attgagcctt ctatcttgta aaatatatct gcataagtat ctaaaacatc
    18241 aaactttcta atcagaaaaa atccaaaaaa tattaaaaac agccaaatta tccaaacact
    18301 ctttgatttt aatattttta tcatttcagc tttaactaaa tacatcattt ctactacacc
    18361 tcccttgcat cttctaaatc aaaataaaac atgtatacat cttcgaattt tgcttgaact
    18421 ggttgtatat tatcctcgct tggaatatcc tctgaaacaa ttctaagtac tattgaatta
    18481 atatcacttt gaatacttac aaccttatat ttagattgta tatcatcaac ttcacattca
    18541 tttttaactt gaacattata tactttattt tccatgtgac ttaatatgtc tttgtgtgtt
    18601 cctttcatta ggagtttgcc atctttaatc attattgttt cctttgcaac tgattctata
    18661 tcggaaatta tatgagtaga aagtattatt atcttatctc tagacatttt tgctattaaa
    18721 ttcctaaatc tagctctttc ttgtgggtca agacctgctg ttggctcatc aaggactatt
    18781 atcttagggt cgtttagtaa aacttgtgct atcccagctc tcctcttcat acctcctgaa
    18841 aattttccta tagacttatt tctcacatca taaagaccta ctaaatctaa taattctcct
    18901 atcttactat ttaaatattt tccccttaaa ccttttaaag ctccaatata ctgtaaaaat
    18961 tcttttgctg taaaattttt ataaactcca aattcttgtg gcaaatatcc taaaatattt
    19021 ctataatcag catccatttt aaatatatcc tcaccattat aaagtatctg accttcatca
    19081 ggttttatca acgttgttat ttgtttcatt aatgtagatt ttcctgctcc atttggtcct
    19141 agaagaccat aaactccatt ttctagagtt actgtaatct tgtcgtttgc tactttttta
    19201 ccatatatct ttgaaagatt ttctatttct aatttattca tcttaactcc ccttttatct
    19261 acttatataa tctgatttta ttactaaaaa acataatgac atagcaccta tcaatattgc
    19321 catcaaaagt cctattgcta tattgacaat gtctatattc actttaaata tcataatatc
    19381 acctagataa tttcctatta ttttattaaa accaaatatc aaatcataat aatttacatt
    19441 tgatacaact gaaagtaatt ttttaggtaa tatatggatt accgacatta tcttagttat
    19501 agatataata aatataaaaa aacttattga agatattgaa gacttactta taaaagaccc
    19561 aaatatggct atcatggccc atccttcaaa catcaaaagc tctatgccta tatttaatat
    19621 tacatacttt gttatactta aattagtttt caatgcaact acattgtcta ctattctaaa
    19681 agattctaag tctccattaa caggtactcc ttgttgcata caagttataa taaatattcc
    19741 cattaaataa acagaataaa ttactaatgg aactaataaa gcaacaaata ttttagaatt
    19801 taatgctttt ttcttctctt ttgatgatag tatgatatct tttaccgaag taacgacttc
    19861 atctacgtaa atattagata taattataga tataatgatt aacattccta catttataag
    19921 tgaatttgta actctatagt taaatacttt ccaaaaacta atatccttat attcattcac
    19981 acttagatta tcaagttttt tctttgacat taattcaatt tttttagaaa attcacctgt
    20041 atctgtttga tttgaaaact gctttaaaac attaatctta ttttgaaatt tctcattacc
    20101 tatgtcgata ccacttctcg tatcttctat acgtcctttt tctttatcta tataataact
    20161 ttctgtttct aaaacaggcg taataaagat actaatcatt agtattaaca ctaatatgcc
    20221 tagagatata aacatactct tagatttagc caattttttt atttcccaat ttacca
//
LOCUS       DAGQVA010000076        19355 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.076, whole genome shotgun sequence.
ACCESSION   DAGQVA010000076 DAGQVA010000000
VERSION     DAGQVA010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19355
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.076"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            117..7043
                     /gene="tcdB"
                     /locus_tag="MIV85_002986"
                     /gene_synonym="toxB"
                     /pseudo
     CDS             117..7043
                     /gene="tcdB"
                     /locus_tag="MIV85_002986"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426838.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
     gene            7165..7665
                     /gene="tcdE"
                     /locus_tag="MIV85_002987"
     CDS             7165..7665
                     /gene="tcdE"
                     /locus_tag="MIV85_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBY2962312.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            7994..8176
                     /locus_tag="MIV85_002988"
     CDS             7994..8176
                     /locus_tag="MIV85_002988"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962313.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            8393..16525
                     /gene="tcdA"
                     /locus_tag="MIV85_002989"
                     /gene_synonym="toxA"
     CDS             8393..16525
                     /gene="tcdA"
                     /locus_tag="MIV85_002989"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBY2962314.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(16860..17558)
                     /gene="tcdC"
                     /locus_tag="MIV85_002990"
     CDS             complement(16860..17558)
                     /gene="tcdC"
                     /locus_tag="MIV85_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBY2962315.1"
                     /translation="MFSKKNDGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            17984..18229
                     /locus_tag="MIV85_002991"
     CDS             17984..18229
                     /locus_tag="MIV85_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBY2962316.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLI
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(18447..18716)
                     /locus_tag="MIV85_002992"
     CDS             complement(18447..18716)
                     /locus_tag="MIV85_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBY2962317.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
BASE COUNT         7636 a         2221 c         2933 g         6565 t
ORIGIN      
        1 acataattag gatatatcta caaaacaata ggatatttta cctattaaaa ttcatataaa
       61 aaatctaact attattatct tttttatata ttaaattgag atataatgaa tatatttata
      121 tagatacata taaaaaatct ggtagaaata aagccttaaa aaaatttaag gaatatctag
      181 ttacagaagt attagagcta aagaataata atttaactcc agttgagaaa aatttacatt
      241 ttgtttggat tggaggtcaa ataaatgaca ctgctattaa ttatataaat caatggaaag
      301 atgtaaatag tgattataat gttaatgttt tttatgatag taatgcattt ttgataaaca
      361 cattgaaaaa aactgtagta gaatcagcaa taaatgatac acttgaatca tttagagaaa
      421 acttaaatga ccctagattt gactataata aattcttcag aaaacgtatg gaaataattt
      481 atgataaaca gaaaaatttc ataaactact ataaagctca aagagaagaa aatcctgaac
      541 ttataattga tgatattgta aagacatatc tttcaaatga gtattcaaag gagatagatg
      601 aacttaatac ctatattgaa gaatccttaa ataaaattac acagaatagt ggaaatgatg
      661 ttagaaactt tgaagaattt aaaaatggag agtcattcaa cttatatgaa caagagttgg
      721 tagaaaggtg gaatttagct gctgcttctg acatattaag aatatctgca ttaaaagaaa
      781 ttggtggtat gtatttagat gttgatatgt taccaggaat acaaccagac ttatttgagt
      841 ctatagagaa acctagttca gtaacagtgg atttttggga aatgacaaag ttagaagcta
      901 taatgaaata caaagaatat ataccagaat atacctcaga acattttgac atgttagacg
      961 aagaagttca aagtagtttt gaatctgttc tagcttctaa gtcagataaa tcagaaatat
     1021 tctcatcact tggtgatatg gaggcatcac cactagaagt taaaattgca tttaatagta
     1081 agggtattat aaatcaaggg ctaatttctg tgaaagactc atattgtagc aatttaatag
     1141 taaaacaaat cgagaataga tataaaatat tgaataatag tttaaatcca gctattagcg
     1201 aggataatga ttttaatact acaacgaata cctttattga tagtataatg gctgaagcta
     1261 atgcagataa tggtagattt atgatggaac taggaaagta tttaagagtt ggtttcttcc
     1321 cagatgttaa aactactatt aacttaagtg gccctgaagc atatgcggca gcttatcaag
     1381 atttattaat gtttaaagaa ggcagtatga atatccattt gatagaagct gatttaagaa
     1441 actttgaaat ctctaaaact aatatttctc aatcaactga acaagaaatg gctagcttat
     1501 ggtcatttga cgatgcaaga gctaaagctc aatttgaaga atataaaagg aattattttg
     1561 aaggttctct tggtgaagat gataatcttg atttttctca aaatatagta gttgacaagg
     1621 agtatctttt agaaaaaata tcttcattag caagaagttc agagagagga tatatacact
     1681 atattgttca gttacaagga gataaaatta gttatgaagc agcatgtaac ttatttgcaa
     1741 agactcctta tgatagtgta ctatttcaga aaaatataga agattcagaa attgcatatt
     1801 attataatcc tggagatggt gaaatacaag aaatagacaa gtataaaatt ccaagtataa
     1861 tttctgatag acctaagatt aaattaacat ttattggtca tggtaaagat gaatttaata
     1921 ctgatatatt tgcaggtttt gatgtagatt cattatccac agaaatagaa gcagcaatag
     1981 atttagctaa agaggatatt tctcctaagt caatagaaat aaatttatta ggatgtaata
     2041 tgtttagcta ctctatcaac gtagaggaga cttatcctgg aaaattatta cttaaagtta
     2101 aagataaaat atcagaatta atgccatcta taagtcaaga ctctattata gtaagtgcaa
     2161 atcaatatga agttagaata aatagtgaag gaagaagaga attattggat cattctggtg
     2221 aatggataaa taaagaagaa agtattataa aggatatttc atcaaaagaa tatatatcat
     2281 ttaatcctaa agaaaataaa attacagtaa aatctaaaaa tttacctgag ctatctacat
     2341 tattacaaga aattagaaat aattctaatt caagtgatat tgaactagaa gaaaaagtaa
     2401 tgttaacaga atgtgagata aatgttattt caaatataga tacgcaaatt gttgaggaaa
     2461 ggattgaaga agctaagaat ttaacttctg actctattaa ttatataaaa gatgaattta
     2521 aactaataga atctatttct gatgcactat gtgacttaaa acaacagaat gaattagaag
     2581 attctcattt tatatctttt gaggacatat cagagactga tgagggattt agtataagat
     2641 ttattaataa agaaactgga gaatctatat ttgtagaaac tgaaaaaaca atattctctg
     2701 aatatgctaa tcatataact gaagagattt ctaagataaa aggtactata tttgatactg
     2761 taaatggtaa gttagtaaaa aaagtaaatt tagatactac acacgaagta aatactttaa
     2821 atgctgcatt ttttatacaa tcattaatag aatataatag ttctaaagaa tctcttagta
     2881 atttaagtgt agcaatgaaa gtccaagttt acgctcaatt atttagtact ggtttaaata
     2941 ctattacaga tgcagccaaa gttgttgaat tagtatcaac tgcattagat gaaactatag
     3001 acttacttcc tacattatct gaaggattac ctataattgc aactattata gatggtgtaa
     3061 gtttaggtgc agcaatcaaa gagctaagtg aaacgagtga cccattatta agacaagaaa
     3121 tagaagctaa gataggtata atggcagtaa atttaacaac agctacaact gcaatcatta
     3181 cttcatcttt gggggtagct agtggattta gtatactttt agttccttta gcaggaattt
     3241 cagcaggtat accaagctta gtaaacaatg aacttgtact tcgagataag gcaacaaagg
     3301 ttgtagatta ttttaaacat gtttcattag ttgaaactga aggagtattt actttattag
     3361 atgataaaat aatgatgcca caagatgatt tagtgatatc agaaatagat tttaataata
     3421 attcaatagt tttaggtaaa tgtgaaatct ggagaatgga aggtggttca ggtcatactg
     3481 taactgatga tatagatcac ttcttttcag caccatcaat aacatataga gagccacact
     3541 tatctatata tgacgtattg gaagtacaaa aagaagaact tgatttgtca aaagatttaa
     3601 tggtattacc taatgctcca aatagagtat ttgcttggga aacaggatgg acaccaggtt
     3661 taagaagctt agaaaatgat ggcacaaaac tgttagaccg tataagagat aactatgaag
     3721 gtgagtttta ttggagatat tttgctttta tagctgatgc tttaataaca acattaaaac
     3781 caagatatga agatactaat ataagaataa atttagatag taatactaga agttttatag
     3841 ttccaataat aactacagaa tatataagag aaaaattatc atattctttc tatggttcag
     3901 gaggaactta tgcattgtct ctttctcaat ataatatggg tataaatata gaattaagtg
     3961 aaagtgatgt ttggattata gatgttgata atgttgtgag agatgtaact atagaatctg
     4021 ataaaattaa aaaaggtgat ttaatagaag gtattttatc tacactaagt attgaagaga
     4081 ataaaattat cttaaatagc catgagatta atttttctgg tgaggtaaat ggaagtaatg
     4141 gatttgtttc tttaacattt tcaattttag aaggaataaa tgcaattata gaagttgatt
     4201 tattatctaa atcatataaa ttacttattt ctggcgaatt aaaaatattg atgttaaatt
     4261 caaatcatat tcaacagaaa atagattata taggattcaa tagcgaatta cagaaaaata
     4321 taccatatag ctttgtagat agtgaaggaa aagagaatgg ttttattaat ggttcaacaa
     4381 aagaaggttt atttgtatct gaattacctg atgtagttct tataagtaag gtttatatgg
     4441 atgatagtaa gccttcattt ggatattata gtaataattt gaaagatgtc aaagttataa
     4501 ctaaagataa tgttaatata ttaacaggtt attatcttaa ggatgatata aaaatctctc
     4561 tttctttgac tctacaagat gaaaaaacta taaagttaaa tagtgtgcat ttagatgaaa
     4621 gtggagtagc tgagattttg aagttcatga atagaaaagg taatacaaat acttcagatt
     4681 ctttaatgag ctttttagaa agtatgaata taaaaagtat tttcgttaat ttcttacaat
     4741 ctaatattaa gtttatatta gatgctaatt ttataataag tggtactact tctattggcc
     4801 aatttgagtt tatttgtgat gaaaatgata atatacaacc atatttcatt aagtttaata
     4861 cactagaaac taattatact ttatatgtag gaaatagaca aaatatgata gtggaaccaa
     4921 attatgattt agatgattct ggagatatat cttcaactgt tatcaatttc tctcaaaagt
     4981 atctttatgg aatagacagt tgtgttaata aagttgtaat ttcaccaaat atttatacag
     5041 atgaaataaa tataacgcct gtatatgaaa caaataatac ttatccagaa gttattgtat
     5101 tagatgcaaa ttatataaat gaaaaaataa atgttaatat caatgatcta tctatacgat
     5161 atgtatggag taatgatggt aatgatttta ttcttatgtc aactagtgaa gaaaataagg
     5221 tgtcacaagt taaaataaga ttcgttaatg tttttaaaga taagactttg gcaaataagc
     5281 tatcttttaa ctttagtgat aaacaagatg tacctgtaag tgaaataatc ttatcattta
     5341 caccttcata ttatgaggat ggattgattg gctatgattt gggtctagtt tctttatata
     5401 atgagaaatt ttatattaat aactttggaa tgatggtatc tggattaata tatattaatg
     5461 attcattata ttattttaaa ccaccagtaa ataatttgat aactggattt gtgactgtag
     5521 gcgatgataa atactacttt aatccaatta atggtggagc tgcttcaatt ggagagacaa
     5581 taattgatga caaaaattat tatttcaacc aaagtggagt gttacaaaca ggtgtattta
     5641 gtacagaaga tggatttaaa tattttgccc cagctaatac acttgatgaa aacctagaag
     5701 gagaagcaat tgattttact ggaaaattaa ttattgacga aaatatttat tattttgatg
     5761 ataattatag aggagctgta gaatggaaag aattagatgg tgaaatgcac tattttagcc
     5821 cagaaacagg taaagctttt aaaggtctaa atcaaatagg tgattataaa tactatttca
     5881 attctgatgg agttatgcaa aaaggatttg ttagtataaa tgataataaa cactattttg
     5941 atgattctgg tgttatgaaa gtaggttaca ctgaaataga tggcaagcat ttctactttg
     6001 ctgaaaacgg agaaatgcaa ataggagtat ttaatacaga agatggattt aaatattttg
     6061 ctcatcataa tgaagattta ggaaatgaag aaggtgaaga aatctcatat tctggtatat
     6121 taaatttcaa taataaaatt tactattttg atgattcatt tacagctgta gttggatgga
     6181 aagatttaga ggatggttca aagtattatt ttgatgaaga tacagcagaa gcatatatag
     6241 gtttgtcatt aataaatgat ggtcaatatt attttaatga tgatggaatt atgcaagttg
     6301 gatttgtcac tataaatgat aaagtcttct acttctctga ctctggaatt atagaatctg
     6361 gagtacaaaa catagatgac aattatttct atatagatga taatggtata gttcaaattg
     6421 gtgtatttga tacttcagat ggatataaat attttgcacc tgctaatact gtaaatgata
     6481 atatttacgg acaagcagtt gaatatagtg gtttagttag agttggggaa gatgtatatt
     6541 attttggaga aacatataca attgagactg gatggatata tgatatggaa aatgaaagtg
     6601 ataaatatta tttcaatcca gaaactaaaa aagcatgcaa aggtattaat ttaattgatg
     6661 atataaaata ttattttgat gagaagggca taatgagaac gggtcttata tcatttgaaa
     6721 ataataatta ttactttaat gagaatggtg aaatgcaatt tggttatata aatatagaag
     6781 ataagatgtt ctattttggt gaagatggtg tcatgcagat tggagtattt aatacaccag
     6841 atggatttaa atactttgca catcaaaata ctttggatga gaattttgag ggagaatcaa
     6901 taaactatac tggttggtta gatttagatg aaaagagata ttattttaca gatgaatata
     6961 ttgcagcaac tggttcagtt attattgatg gtgaggagta ttattttgat cctgatacag
     7021 ctcaattagt gattagtgaa tagataaaaa tatgttaaat atatcctctt atacttaaat
     7081 atataaaaat aaacaaaatg atacactaca taaagtgttc tatctaatat gaagatttac
     7141 caataaaaag gtggactatg atgaatgcac agtagttcac ctttttatat ttctaatggt
     7201 aacaaaatat ttttttatat aaacctagga ggcgttatga atatgacaat atctttttta
     7261 tcagagcata tatttataaa gttagtaatt ttaactatat catttgatac attattagga
     7321 tgtttaagtg caataaaaag tcgtaaattt aattctagtt ttggaataga tggaggaatc
     7381 agaaaagtag caatgatagc atgtatattt tttttatcag tagttgacat tcttacaaag
     7441 tttaactttt tatttatgtt accacaagat tgtatcaatt ttttaagact aaaacatctt
     7501 ggaatatctg aatttttctc tattttattt attttatatg aaagtgtaag tatattaaaa
     7561 aatatgtgct tatgtggatt accagtacct aagagattaa aggaaaaaat agcaatttta
     7621 ctagatgcaa tgacagatga aatgaatgct aaggatgaaa agtaagtaat ggtagatata
     7681 ataaagatat taacaaataa aaagtgttat ccaaataaga atagctgaaa gttatcataa
     7741 ttcatgaaac taataatgaa aacgagggag cagatgccaa gagacacaca agtattaaat
     7801 acatataatt tcgaagcaag tgttcattac tatatagatg acaaggtagt atatcaaaca
     7861 ttggttcaca aagatggtgc atggtcagtt ggtaaaatct attaagctac attagttaca
     7921 gatatcacaa actataatag ttaaacatag aaatatgtgt aaattgtgat ggaaattatt
     7981 caaaaacaca aaaatacgtg atgaaggaca aaatgatata gaaaataagt atcaaacctt
     8041 aataaatgat ttaattgata gtttaaaagt tataggaaaa atatataaag aaataaaaac
     8101 attaaaaaaa tataagatat gtttacaaat tactatcaga caatctcctt atctaataga
     8161 agagtcaatt aactaattga gtatctttaa attgaaatgt taggaagtga tttaaatatg
     8221 aaaacttaaa ttataaaaaa tcaatattaa tttattttta aaaaatagaa aggagtgtat
     8281 aagatttatt ttcaaagttt aaaaacaaga aaatcaattt aaatttcaga aggaataaat
     8341 gtggttatag aagtggattt attatcaaaa ataataatac taggaggttt ttatgtcttt
     8401 aatatctaaa gaagagttaa taaaactcgc atatagcatt agaccaagag aaaatgagta
     8461 taaaactata ctaactaatt tagacgaata taataagtta actacaaaca ataatgaaaa
     8521 taaatattta caattaaaaa aactaaatga atcaattgat gtttttatga ataaatataa
     8581 aacttcaagc agaaatagag cactctctaa tctaaaaaaa gatatattaa aagaagtaat
     8641 tcttattaaa aattccaata caagccctgt agaaaaaaat ttacattttg tatggatagg
     8701 tggagaagtc agtgatattg ctcttgaata cataaaacaa tgggctgata ttaatgcaga
     8761 atataatatt aaactgtggt atgatagtga agcattctta gtaaatacac taaaaaaggc
     8821 tatagttgaa tcttctacca ctgaagcatt acagctacta gaggaagaga ttcaaaatcc
     8881 tcaatttgat aatatgaaat tttacaaaaa aaggatggaa tttatatatg atagacaaaa
     8941 aaggtttata aattattata aatctcaaat caataaacct acagtaccta caatagatga
     9001 tattataaag tctcatctag tatctgaata taatagagat gaaactgtat tagaatcata
     9061 tagaacaaat tctttgagaa aaataaatag taatcatggg atagatatca gggctaatag
     9121 tttgtttaca gaacaagagt tattaaatat ttatagtcag gagttgttaa atcgtggaaa
     9181 tttagctgca gcatctgaca tagtaagatt attagcccta aaaaattttg gcggagtata
     9241 tttagatgtt gatatgcttc caggtattca ctctgattta tttaaaacaa tatctagacc
     9301 tagctctatt ggactagacc gttgggaaat gataaaatta gaggctatta tgaagtataa
     9361 aaaatatata aataattata catcagaaaa ctttgataaa cttgatcaac aattaaaaga
     9421 taattttaaa ctcattatag aaagtaaaag tgaaaaatct gagatatttt ctaaattaga
     9481 aaatttaaat gtatctgatc ttgaaattaa aatagctttc gctttaggca gtgttataaa
     9541 tcaagccttg atatcaaaac aaggttcata tcttactaac ctagtaatag aacaagtaaa
     9601 aaatagatat caatttttaa accaacacct taacccagcc atagagtctg ataataactt
     9661 cacagatact actaaaattt ttcatgattc attatttaat tcagctaccg cagaaaactc
     9721 tatgttttta acaaaaatag caccatactt acaagtaggt tttatgccag aagctcgctc
     9781 cacaataagt ttaagtggtc caggagctta tgcgtcagct tactatgatt tcataaattt
     9841 acaagaaaat actatagaaa aaactttaaa agcatcagat ttaatagaat ttaaattccc
     9901 agaaaataat ctatctcaat tgacagaaca agaaataaat agtctatgga gctttgatca
     9961 agcaagtgca aaatatcaat ttgagaaata tgtaagagat tatactggtg gatctctttc
    10021 tgaagacaat ggggtagact ttaataaaaa tactgccctc gacaaaaact atttattaaa
    10081 taataaaatt ccatcaaaca atgtagaaga agctggaagt aaaaattatg ttcattatat
    10141 catacagtta caaggagatg atataagtta tgaagcaaca tgcaatttat tttctaaaaa
    10201 tcctaaaaat agtattatta tacaacgaaa tatgaatgaa agtgcaaaaa gctacttttt
    10261 aagtgatgat ggagaatcta ttttagaatt aaataaatat aggatacctg aaagattaaa
    10321 aaataaggaa aaagtaaaag taacctttat tggacatggt aaagatgaat tcaacacaag
    10381 cgaatttgct agattaagtg tagattcact ttccaatgag ataagttcat ttttagatac
    10441 cataaaatta gatatatcac ctaaaaatgt agaagtaaac ttacttggat gtaatatgtt
    10501 tagttatgat tttaatgttg aagaaactta tcctgggaag ttgctattaa gtattatgga
    10561 caaaattact tccactttac ctgatgtaaa taaaaattct attactatag gagcaaatca
    10621 atatgaagta agaattaata gtgagggaag aaaagaactt ctggctcact caggtaaatg
    10681 gataaataaa gaagaagcta ttatgagcga tttatctagt aaagaataca ttttttttga
    10741 ttctatagat aataagctaa aagcaaagtc caagaatatt ccaggattag catcaatatc
    10801 agaagatata aaaacattat tacttgatgc aagtgttagt cctgatacaa aatttatttt
    10861 aaataatctt aagcttaata ttgaatcttc tattggtgat tacatttatt atgaaaaatt
    10921 agagcctgtt aaaaatataa ttcacaattc tatagatgat ttaatagatg agttcaatct
    10981 acttgaaaat gtatctgatg aattatatga attaaaaaaa ttaaataatc tagatgagaa
    11041 gtatttaata tcttttgaag atatctcaaa aaataattca acttactctg taagatttat
    11101 taacaaaagt aatggtgagt cagtttatgt agaaacagaa aaagaaattt tttcaaaata
    11161 tagcgaacat attacaaaag aaataagtac tataaagaat agtataatta cagatgttaa
    11221 tggtaattta ttggataata tacagttaga tcatacttct caagttaata cattaaacgc
    11281 agcattcttt attcaatcat taatagatta tagtagcaat aaagatgtac tgaatgattt
    11341 aagtacctca gttaaggttc aactttatgc tcaactattt agtacaggtt taaatactat
    11401 atatgactct atccaattag taaatttaat atcaaatgca gtaaatgata ctataaatgt
    11461 actacctaca ataacagagg ggatacctat tgtatctact atattagacg gaataaactt
    11521 aggtgcagca attaaggaat tactagacga acatgaccca ttactaaaaa aagaattaga
    11581 agctaaggtg ggtgttttag caataaatat gtcattatct atagctgcaa ctgtagcttc
    11641 aattgttgga ataggtgctg aagttactat tttcttatta cctatagctg gtatatctgc
    11701 aggaatacct tcattagtta ataatgaatt aatattgcat gataaggcaa cttcagtggt
    11761 aaactatttt aatcatttgt ctgaatctaa aaaatatggc cctcttaaaa cagaagatga
    11821 taaaatttta gttcctattg atgatttagt aatatcagaa atagatttta ataataattc
    11881 gataaaacta ggaacatgta atatattagc aatggagggg ggatcaggac acacagtgac
    11941 tggtaatata gatcactttt tctcatctcc atctataagt tctcatattc cttcattatc
    12001 aatttattct gcaataggta tagaaacaga aaatctagat ttttcaaaaa aaataatgat
    12061 gttacctaat gctccttcaa gagtgttttg gtgggaaact ggagcagttc caggtttaag
    12121 atcattggaa aatgacggaa ctagattact tgattcaata agagatttat acccaggtaa
    12181 attttactgg agattctatg cttttttcga ttatgcaata actacattaa aaccagttta
    12241 tgaagacact aatattaaaa ttaaactaga taaagatact agaaacttca taatgccaac
    12301 tataactact aacgaaatta gaaacaaatt atcttattca tttgatggag caggaggaac
    12361 ttactcttta ttattatctt catatccaat atcaacgaat ataaatttat ctaaagatga
    12421 tttatggata tttaatattg ataatgaagt aagagaaata tctatagaaa atggtactat
    12481 taaaaaagga aagttaataa aagatgtttt aagtaaaatt gatataaata aaaataaact
    12541 tattataggc aatcaaacaa tagatttttc aggcgatata gataataaag atagatatat
    12601 attcttgact tgtgagttag atgataaaat tagtttaata atagaaataa atcttgttgc
    12661 aaaatcttat agtttgttat tgtctgggga taaaaattat ttgatatcca atttatctaa
    12721 tactattgag aaaatcaata ctttaggcct agatagtaaa aatatagcgt acaattacac
    12781 tgatgaatct aataataaat attttggagc tatatctaaa acaagtcaaa aaagcataat
    12841 acattataaa aaagacagta aaaatatatt agaattttat aatgacagta cattagaatt
    12901 taacagtaaa gattttattg ctgaagatat aaatgtattt atgaaagatg atattaatac
    12961 tataacagga aaatactatg ttgataataa tactgataaa agtatagatt tctctatttc
    13021 tttagttagt aaaaatcaag taaaagtaaa tggattatat ttaaatgaat ccgtatactc
    13081 atcttacctt gattttgtga aaaattcaga tggacaccat aatacttcta attttatgaa
    13141 tttatttttg gacaatataa gtttctggaa attgtttggg tttgaaaata taaattttgt
    13201 aatcgataaa tactttaccc ttgttggtaa aactaatctt ggatatgtag aatttatttg
    13261 tgacaataat aaaaatatag atatatattt tggtgaatgg aaaacatcgt catctaaaag
    13321 cactatattt agcggaaatg gtagaaatgt tgtagtagag cctatatata atcctgatac
    13381 gggtgaagat atatctactt cactagattt ttcctatgaa cctctctatg gaatagatag
    13441 atatatcaat aaagtattga tagcacctga tttatataca agtttaataa atattaatac
    13501 caattattat tcaaatgagt actaccctga gattatagtt cttaacccaa atacattcca
    13561 caaaaaagta aatataaatt tagatagttc ttcttttgag tataaatggt ctacagaagg
    13621 aagtgacttt attttagtta gatacttaga agaaagtaat aaaaaaatat tacaaaaaat
    13681 aagaatcaaa ggtatcttat ctaatactca atcatttaat aaaatgagta tagattttaa
    13741 agatattaaa aaactatcat taggatatat aatgagtaat tttaaatcat ttaattctga
    13801 aaatgaatta gatagagatc atttaggatt taaaataata gataataaaa cttattacta
    13861 tgatgaagat agtaaattag ttaaaggatt aatcaatata aataattcat tattctattt
    13921 tgatcctata gaatttaact tagtaactgg atggcaaact atcaatggta aaaaatatta
    13981 ttttgatata aatactggag cagctttaac tagttataaa attattaatg gtaaacactt
    14041 ttattttaat aatgatggtg tgatgcagtt gggagtattt aaaggacctg atggatttga
    14101 atattttgca cctgccaata ctcaaaataa taacatagaa ggtcaggcta tagtttatca
    14161 aagtaaattc ttaactttga atggcaaaaa atattatttt gataatgact caaaagcagt
    14221 cactggatgg agaattatta acaatgagaa atattacttt aatcctaata atgctattgc
    14281 tgcagtcgga ttgcaagtaa ttgacaataa taagtattat ttcaatcctg acactgctat
    14341 catctcaaaa ggttggcaga ctgttaatgg tagtagatac tactttgata ctgataccgc
    14401 tattgccttt aatggttata aaactattga tggtaaacac ttttattttg atagtgattg
    14461 tgtagtgaaa ataggtgtgt ttagtacctc taatggattt gaatattttg cacctgctaa
    14521 tacttataat aataacatag aaggtcaggc tatagtttat caaagtaaat tcttaacttt
    14581 gaatggtaaa aaatattact ttgataataa ctcaaaagca gttaccggat ggcaaactat
    14641 tgatagtaaa aaatattact ttaatactaa cactgctgaa gcagctactg gatggcaaac
    14701 tattgatggt aaaaaatatt actttaatac taacactgct gaagcagcta ctggatggca
    14761 aactattgat ggtaaaaaat attactttaa tactaacact gctatagctt caactggtta
    14821 tacaattatt aatggtaaac atttttattt taatactgat ggtattatgc agataggagt
    14881 gtttaaagga cctaatggat ttgaatattt tgcacctgct aatacggatg ctaacaacat
    14941 agaaggtcaa gctatacttt accaaaatga attcttaact ttgaatggta aaaaatatta
    15001 ctttggtagt gactcaaaag cagttactgg atggagaatt attaacaata agaaatatta
    15061 ctttaatcct aataatgcta ttgctgcaat tcatctatgc actataaata atgacaagta
    15121 ttactttagt tatgatggaa ttcttcaaaa tggatatatt actattgaaa gaaataattt
    15181 ctattttgat gctaataatg aatctaaaat ggtaacagga gtatttaaag gacctaatgg
    15241 atttgagtat tttgcacctg ctaatactca caataataac atagaaggtc aggctatagt
    15301 ttaccagaac aaattcttaa ctttgaatgg caaaaaatat tattttgata atgactcaaa
    15361 agcagttact ggatggcaaa ccattgatgg taaaaaatat tactttaatc ttaacactgc
    15421 tgaagcagct actggatggc aaactattga tggtaaaaaa tattacttta atcttaacac
    15481 tgctgaagca gctactggat ggcaaactat tgatggtaaa aaatattact ttaatactaa
    15541 cactttcata gcctcaactg gttatacaag tattaatggt aaacattttt attttaatac
    15601 tgatggtatt atgcagatag gagtgtttaa aggacctaat ggatttgaat actttgcacc
    15661 tgctaatact cataataata acatagaagg tcaagctata ctttaccaaa ataaattctt
    15721 aactttgaat ggtaaaaaat attactttgg tagtgactca aaagcagtta ccggattgcg
    15781 aactattgat ggtaaaaaat attactttaa tactaacact gctgttgcag ttactggatg
    15841 gcaaactatt aatggtaaaa aatactactt taatactaac acttctatag cttcaactgg
    15901 ttatacaatt attagtggta aacattttta ttttaatact gatggtatta tgcagatagg
    15961 agtgtttaaa ggacctgatg gatttgaata ctttgcacct gctaatacag atgctaacaa
    16021 tatagaaggt caagctatac gttatcaaaa tagattccta tatttacatg acaatatata
    16081 ttattttggt aataattcaa aagcggctac tggttgggta actattgatg gtaatagata
    16141 ttacttcgag cctaatacag ctatgggtgc gaatggttat aaaactattg ataataaaaa
    16201 tttttacttt agaaatggtt tacctcagat aggggtgttt aaagggtcta atggatttga
    16261 atactttgca cctgctaata cggatgctaa caatatagaa ggtcaagcta tacgttatca
    16321 aaatagattc ctacatttac ttggaaaaat atattacttt ggtaataatt caaaagcagt
    16381 tactggatgg caaactatta atggtaaagt atattacttt atgcctgata ctgctatggc
    16441 tgcagctggt ggactttttg agattgatgg tgttatatat ttctttggtg ttgatggagt
    16501 aaaagcccct gggatatatg gctaaaatat atgtttgata aaaaattatt cctgtgctac
    16561 taagaaatta tttttatata ataaatattg agatttaatt aaaagtcatg tgttattgta
    16621 atacatgact tttagttaaa atttttctat catttaataa tctattattc ttgactattt
    16681 tataataaaa ttcatatatg gaaatattaa tactaaataa ttaatagttg ataaaaaata
    16741 gataatatgc taaaagcaaa aactaattta gagccttgta actgtttatt tgcaattata
    16801 aaaacatctt taaacatatt gactataata taaaatatta actataatac aaaacaatat
    16861 taattaattt tctctacagc tatccctggt atagttatat ttccacccat agttgattca
    16921 taagttatag ttccagcact tatacctctt atagttatgt aatcatcctc taatactctt
    16981 gaaggagtta ttgatttttt ataactacat agtacaacct tatcataatt tccagacaca
    17041 gctaatctta tttgcacctc atcaccatct tcaataactt gaataacctt accttcaaat
    17101 tttacctttt tgtacttata atcatcaggt gttctagcta attggtcata agtaatacca
    17161 gtatcatatc ctttcttctc ctcttcttct tttttgcgtt gttcttcagc ctttttagct
    17221 tcttcagctt ttttagcttc ttcagcttta cgttgatttt cagcttcaat agctttcttt
    17281 tcgtcgtctt tcattttgaa ccatggttca gcatcagaca atttgctatt taaagtttct
    17341 atttctgttt tttgagaatc tataactgat gtttggttag aaatgacctc ctcatggtct
    17401 tcagaacaag ctggtgagga tatattgcca aaaaacacgc ctaaaataaa tgccagtaga
    17461 gcaataccct ttgtgctctt aaagaattta attattttct tagagcttcc ttttccttca
    17521 ttactaaatt cgttaccatc atttttttta gaaaacataa tacaatctcc cttttattag
    17581 atatatttta ttttaaaagt taaaaactta aaataactag ttgactaaaa attatatatt
    17641 catattttcc taaaatatat ttcccctaag cataatttta caaaataaag taagaagatt
    17701 caatatattt tgaaaaaata agataaaaat gtcagattat aatataattt tcttgaaggt
    17761 gaattttata tattaaatta aacataaagt attttatttg tataaaacta tattatgatg
    17821 taattaagtg actcagtgat ttagaggtgg taaaatatat atatatgaaa gagcataaat
    17881 aaattgatat aataaaaaat taaatattaa atattaacta taataaaaaa atatctggta
    17941 ataggtataa tataaaaaga atataccaga aagaaggtga agtatgggag aactacaaaa
    18001 aattccaggg gtagggaaag caacagaaaa atctttaatc atgttaggat atacaactat
    18061 taaatcactt aaagatgcaa acccagcaca aatgtatgaa aaggaatgtt taatacgtgg
    18121 acagcacata gacagatgtc agttatatgt atacagatgt gcagtatatt ttgcatcaac
    18181 tgaaaatcca gaaccagaaa aattaaagtg gtggtattgg aaagattaaa aaatcaaaaa
    18241 agttagacat aaaaaagagt tgaatatccg ttttaaataa taaaaactaa tactcaactc
    18301 ttttttagtc gtaaatttta tgtaaatcta tttgtatggc taaatatacc catcaataaa
    18361 tgtataaata taccaatcaa caaatgacta aacatactac ctaacaaagg attaaataaa
    18421 ttacttaaca aagcattcta aaacaattaa ttagaaactg tttcttcaag ccattttcta
    18481 cattgctcaa tatttaccat agggtcaaaa ccttggtctt ttcccttatt taaaagcata
    18541 tcacaaggga aagtatcaca ttcaccacaa tgattaagtt ccttactttc acagcaagtt
    18601 ttaaccttac attctccacc ccaaaatggt ttttccatag ttgggcaacc agtgcaattt
    18661 acttgttctt tttttgtaca actgtcacaa cagacaccac atcttgattc aaacatgttc
    18721 aaacatcctt tccattattt aaaaatatta taaaatgatt ttagatgaat acaaaagtgc
    18781 aaatagttga ttttaggtca tctaaatgtt aaacataaaa ttattagtac tggtaaattt
    18841 ataaaaacta ttccaaaaat ctttttgaat atttcaaaac acaataaatt acttcaaatc
    18901 cctttgaata tattttacag cattatagat tgctttaaat ctctttgaat attctacaag
    18961 actatagatt agtttaaatc cctttgaata tattttacaa cattatagat tgttttaaat
    19021 ctctttgaat attctacaag actatagatt agtttaaatc cctttgaata tttcaaaaca
    19081 ccatagatta ctttaaatcc ctttgaatat tctataacac tataaattac ttttaacttt
    19141 tatataacca taaagttttt atctggcact ttaaatggag ttttatatca aatttgcctt
    19201 ccatcgaata accaaactta atttaattac acattccaag agtcaaatat tcattcaata
    19261 tatttgataa ttctatgtta tagctataat taaatataga ttattaaagt taaatattta
    19321 tttaatatat tgaatgattt tttacctata tttaa
//
LOCUS       DAGQVA010000077        18900 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.077, whole genome shotgun sequence.
ACCESSION   DAGQVA010000077 DAGQVA010000000
VERSION     DAGQVA010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.077"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..255
                     /locus_tag="MIV85_002993"
     CDS             <1..255
                     /locus_tag="MIV85_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBY2962318.1"
                     /translation="KVPSNLMKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQF
                     SKLDEPTAVTEGKFFYFEESFEDVFILNKKADAIQFVVEA"
     gene            274..507
                     /locus_tag="MIV85_002994"
     CDS             274..507
                     /locus_tag="MIV85_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962319.1"
                     /translation="MPQVKKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLSV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            517..918
                     /locus_tag="MIV85_002995"
     CDS             517..918
                     /locus_tag="MIV85_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962320.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            912..1259
                     /locus_tag="MIV85_002996"
     CDS             912..1259
                     /locus_tag="MIV85_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962321.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            1259..1549
                     /locus_tag="MIV85_002997"
     CDS             1259..1549
                     /locus_tag="MIV85_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBY2962322.1"
                     /translation="MARWGSVDFREFKRVCKKMEELTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            1659..2465
                     /locus_tag="MIV85_002998"
     CDS             1659..2465
                     /locus_tag="MIV85_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962323.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNNLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            2814..3251
                     /locus_tag="MIV85_002999"
     CDS             2814..3251
                     /locus_tag="MIV85_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962324.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRTLKKNSFDVHYFPKSNDKSFEIDEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIVDNVLHFFVDYNYFTIKNNDINKMDTVELFGGLKRGDNFE"
     gene            3244..3420
                     /locus_tag="MIV85_003000"
     CDS             3244..3420
                     /locus_tag="MIV85_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962325.1"
                     /translation="MSKTLSKGTDYKFTKEQIVNSKKYINRKDLLNAILKENELYSFS
                     EVEEIINSFMKGVS"
     gene            3422..4732
                     /locus_tag="MIV85_003001"
     CDS             3422..4732
                     /locus_tag="MIV85_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBY2962326.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDIGLVESSLIYWAAGVIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVN"
     gene            4749..5219
                     /locus_tag="MIV85_003002"
     CDS             4749..5219
                     /locus_tag="MIV85_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBY2962327.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVEKFNLLAGME"
     gene            5291..5731
                     /locus_tag="MIV85_003003"
     CDS             5291..5731
                     /locus_tag="MIV85_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBY2962328.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            6072..6233
                     /locus_tag="MIV85_003004"
     CDS             6072..6233
                     /locus_tag="MIV85_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962329.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
     repeat_region   6971..7394
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6971..6999
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            7558..7731
                     /locus_tag="MIV85_003005"
     CDS             7558..7731
                     /locus_tag="MIV85_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HBY2962330.1"
                     /translation="MSSKMGRPKVDNPKNIDVKVRFDENTHKKLLDYCEKENLTRTEA
                     IRKGVDLLLEEDK"
     gene            7855..8682
                     /locus_tag="MIV85_003006"
     CDS             7855..8682
                     /locus_tag="MIV85_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBY2962331.1"
                     /translation="MNNELMNFENNELGIKIRTIKYEDGSIGINAEDTAVGFGWCQTQ
                     NKNGKQYVSIRWETINKYCKEFGFLNLLGKDEYIPESLFYLLGMKAKNEIAVKFQTWL
                     AVDVLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLKELLDGAGFDNKSK
                     LLTAKTLYKKAGIDLPIEIEEEESFFDTKQIASKLKIYSKSNKPAQLAVCEIIKKIDL
                     EENEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPAKIAGEKKNYHVVYKIE"
     gene            8745..8921
                     /locus_tag="MIV85_003007"
     CDS             8745..8921
                     /locus_tag="MIV85_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962332.1"
                     /translation="MCENLLNEYNLKTDEDVEYFVKFATLLYKLKQDNEEKFQEYAEI
                     LRGILREQQERENK"
     gene            complement(9334..9537)
                     /locus_tag="MIV85_003008"
     CDS             complement(9334..9537)
                     /locus_tag="MIV85_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008982964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962333.1"
                     /translation="MYFNIDKLLESKGRTRYWLAKEVGIAYPNMMKLANNETSSIKLD
                     LFEKLCLVLECTPNELVTLSSKE"
     gene            9781..10167
                     /locus_tag="MIV85_003009"
                     /pseudo
     CDS             9781..10167
                     /locus_tag="MIV85_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013726857.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
     gene            10231..10584
                     /locus_tag="MIV85_003010"
     CDS             10231..10584
                     /locus_tag="MIV85_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962334.1"
                     /translation="MKLLVTKTFFERAGIELPLEVEEKEHFYDTKQIAKKLGLYTMSN
                     KPAFMAVKQIIRKLDIKEDEMKTVLETNGNWTGTVTKYSNKVTEKVKVWLKENNNPIS
                     IKGDKKNYYILYKNN"
     repeat_region   11016..11967
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=11016..11044
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaat"
     gene            12097..12612
                     /locus_tag="MIV85_003011"
     CDS             12097..12612
                     /locus_tag="MIV85_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBY2962335.1"
                     /translation="MFCSNCGYEITGAGKFCSNCGTATLADKVNNDDLFINVHGKELN
                     LTNIYKETKGDKILAIDIAMKLLGLDIKECKNIIYPAFKELSEKINIEEEKEILREDE
                     YKQTNVLEDDVARCPRCGSVSLSAHKKGFGIGKAVAGATIAGGIGLVAGNLGAKKVRV
                     TCLSCGKQFWA"
     gene            12677..15070
                     /locus_tag="MIV85_003012"
     CDS             12677..15070
                     /locus_tag="MIV85_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBY2962336.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTNSINTTINSLERLQGRLNNPLN
                     AGNIQASQQSLNNIESILTRIEQKIGRNTNEQENFNNKIRQGSEAGSLLVSKLKSIAG
                     IYIGIKGIDSITKVADTIASTKARLNLMNDGLQTTDQLNKMIYLSAQSARASYADTAA
                     QIAKLGILAGDAFGSSAEVIKFTELMNKAFVIGGTSANEASAAMYQLTQAMGAGKLQG
                     DEFRSIMENAPLLATKIADAMGKTKDQLKELSSSGAITADVIRNALFKASDEIEKKFA
                     SMAITFSQALTMMKNDAYMIFSETLSKISGALQSVRFSEIVVSMRNVMIAISSNIYDT
                     LNIIKNILNSDFFSDFVSNVTLGAILIINGLGWVTNATLNVANVFAQNWSIIAPIIYG
                     VIAAIAIYKGVLLASTIATTVASFVNSLYAVAAYKSCAALAAQEFAIFGKISAQTMEA
                     LVTAQATAAQWGFNAALLSCPIFWIIAGIIAFVVVVFVAVAAVNKFSGTSLTVLGAIV
                     GAVFAAVAFIQNIMIWLFNRCVDVNEGIANGWNQCVYLMKQAIAKGVIFIIEKMASLN
                     DAVNNAGNALGKAFIDGANIAIRGVNKLIDLINKIPGINIGKVGEATFTPVKADNSYI
                     KQQIDSLNKWVGDAPEKIKLDRMGYKDIGAEFQKGNALGTKWQNAITDKFKDTFDINK
                     MLEDAKKKLGLDDLWNKQNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKY
                     LRDIAEQETINRFTGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMIVSAEGIV"
     gene            15086..15775
                     /locus_tag="MIV85_003013"
     CDS             15086..15775
                     /locus_tag="MIV85_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBY2962337.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKIVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKKVPKY
                     TIYKGQVLRLV"
     gene            15768..17660
                     /locus_tag="MIV85_003014"
     CDS             15768..17660
                     /locus_tag="MIV85_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBY2962338.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPAVIDGITWEIERRGSPSK
                     LEFTIAMDDILEFCEGNSVRIYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSITKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDVLLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            17674..17934
                     /locus_tag="MIV85_003015"
     CDS             17674..17934
                     /locus_tag="MIV85_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBY2962339.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            17939..18358
                     /locus_tag="MIV85_003016"
     CDS             17939..18358
                     /locus_tag="MIV85_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBY2962340.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFENIKGKVQCKFSVHTKYGNIKAEKVVSV"
     gene            18371..>18900
                     /locus_tag="MIV85_003017"
     CDS             18371..>18900
                     /locus_tag="MIV85_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBY2962341.1"
                     /translation="MTFENIIKRMLDSVPNTLDKREGSIIYNALAPVAVELTETYIAM
                     DELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPLDSRFNLGEYNYI
                     AIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETAELTEILINGEDEESEDSLRQ
                     RYYDSLNSQSFGGNIQ"
BASE COUNT         7507 a         1978 c         3594 g         5821 t
ORIGIN      
        1 aaagtaccat ctaatctaat gaaaactgca tatgatttta caactggatg gaaagtagga
       61 gcaggagcta aacaaatctt tatgtcctta gttcacccaa gtgcaataat tacacctgtt
      121 tcttatcagt tctctaagtt agacgaacca acagcagtta cagagggaaa attcttctac
      181 tttgaagaaa gttttgagga tgtatttata ttaaataaaa aagctgatgc aatacaattt
      241 gttgttgaag catagaaaaa ggagtgatat atagtgccac aagtaaaaaa actaaataga
      301 atactaacca tagaagaatg taaaatagat gatttcttag agatgggata tgatttgata
      361 gatgaaactg gtaaggcagt aaagtatggc aagtcattaa gtgtaaaaga tttaatagct
      421 gaaaataata ttttaaggtc aaaagttgag tctttagaag aagaaaataa gcagcttaaa
      481 gagaaaaata aacttactaa aaagtaggtg aaaattatgg aaaataatat aattgatgaa
      541 atagaaaaaa gacttgaaag ttttggatat atattaaaag atggagataa gtggttaata
      601 ggttttgtaa gagaaaaaat agaaaatatt attaaactag attgtaatat aaaaactatg
      661 ccaattgaat tgaaagaaat tgaagttgat atgatagttg gagagttctt atttaccaag
      721 aaaaatatgg gtcaattaga tatagaaagc attaactttg aagctgtaga aaagtctata
      781 tcagaaggtg atacaaaggt agattttgct ataggaagtg gttctcaaac accagaacaa
      841 cgctttgata gcttaatagc ttatcttact acttatggca agaataagat attaaccttt
      901 aggtgcttaa gatggtaagt aaaactagaa aagcaataga aatgttatat agagataaat
      961 gtactatagt tgagtatcag ccaattaaag accctgtaac aaaacgaact aacaataaag
     1021 aagtgattgt attagaaaat caaccatgta aactttcata taaaaatata gtttctgcta
     1081 cagaagggaa agtagctaag ctagagcaaa ctattaaact ctttatatct ccagatatag
     1141 aaattaaagc aggttcaaaa cttattataa atgataaaga gtatgtaaga agtggagaat
     1201 cagctatata tccaaatcat caagaaataa tacttgagtt atttaaggat aaagcataat
     1261 ggctagatgg ggcagtgttg attttagaga gtttaaaaga gtttgtaaaa agatggagga
     1321 gcttacaaag attgatttag ataagttttg caaggatgca gcaagagaat tagcagcacg
     1381 attacttggg aaagtaatta gaagaacacc agttgataca ggattcttac gacaaggatg
     1441 gaatggagtg gcttatgcta ggtcgcttcc tgtgtataaa caaggaaata attatattat
     1501 agaggttgtt aatccgactg aatatgcctt aacacaatgg ggcatataaa acccagcaaa
     1561 atcggtaaac gctaagtgta atagtgttac attataaagt aggtagaata tggacataga
     1621 ataactcttg atttataatg tataaaagag gtgattttat ggcaaaattt ttagatatta
     1681 caggaaaaaa atttggaagg ctaagagtca ttaaattttc taaagagata aaaagtggta
     1741 aaagaaatag aaaatattgg ttatgtaagt gtgattgtgg aaatttcaaa gaaataagaa
     1801 ctgactcttt aactagtggc ttagtacaat cttgtggatg tttaaaaaaa gaacaagata
     1861 aattaaattt aacagacaaa taccaattta aaaagaaata taaggttcaa aataaaagac
     1921 tttacagtat atggaagggt ataatatcta gatgtacaga taaaaataat aaaagataca
     1981 atagatatgg tgaaaggaat ataattgtgt gtgatgaatg gttttgctat gataattttg
     2041 caaattgggc attgagtaat ggatattcag agaaacttac aattgataga ataaataatg
     2101 aaggaaatta tgaatcaagc aattgtagat gggtggatat aaagacacaa tgtagaaata
     2161 ggtcaacaaa tatattagta aagcatgaag aaaaagaaat tacattgata gagctttctg
     2221 aaaaaacagg tatttcatat tcttgcttaa gaagtagata ttctaaggga ttagtaggaa
     2281 ataatcttat agaaaaagtt aagattattg aagaaagcag agctaagtta tctattgagg
     2341 atgtaaaaga aattagaaaa aagtattctg atggatatac aataaaacaa ctaagtgaaa
     2401 tatatcctgt aacatattca tctatatcaa atatagtcca tagaagaaca tggaaaaata
     2461 tttaattaat tatatatgcc aataccgagg aaaacctata gattgcgaat aggctatagg
     2521 tttccgtaga gcgtagagag tgaataaata taatctctcc aagagtgctg ggcaactaaa
     2581 taaagtttat tttgttgatg atgtacgccg aacttatagg aaactataag agctagagga
     2641 taaaaagcct ttaggataac aaaatgcata tgttgaatat ggccatagaa ctaaagatgg
     2701 aaaaggttgg gttaaaggac aacatttctt aacaatttca gagatggaac tacaaagcca
     2761 agttgataag attatagaga aaaaactatt aatattgctt aaaggagtat ttgatgctta
     2821 ataatataat tgatggaata tctattaaat tagataaaac atttggagag agttatacaa
     2881 tttatagtga agatgtggag caaggtataa atgaaccttg tttttttatt gttcctttaa
     2941 atccaagcaa agtatcctat ccaagtggca ggacattaaa aaagaactct tttgatgtac
     3001 attattttcc aaaaagtaat gataaatcat ttgaaataga tgaggtagct gagatgctac
     3061 tggaggaatt agagtatata gaaattgatg gagatttagt cagaggtaca aatatgaact
     3121 ttgaaattgt agataatgta cttcatttct ttgttgatta taactacttt actataaaaa
     3181 ataatgatat caataagatg gatacagtag agttattcgg tggtttgaag agaggtgata
     3241 attttgagta agacattaag taaaggaacc gattacaagt ttactaagga gcagatagtt
     3301 aattctaaga agtatataaa tagaaaagac ttattaaatg caattttaaa agaaaatgag
     3361 ttatattcct tctcagaggt agaggaaata ataaatagct ttatgaaagg agtgagttaa
     3421 tttggcgtta ggtggaggaa catttgtaac acagaataaa atattaccag gtagctatat
     3481 aaattttatc tcagctaaga gggcaaccag ttcattatcg gatagaggta ttgttgcaat
     3541 acctttagag ttagattggg gcatagatga agacgtattt caagtaacca gtgatgattt
     3601 tgagaagtat tcagtgaagt attttggata tgattatact catgagaagc tgaaaggttt
     3661 gagagattta ttcaaaaata taaggttggg atatttttat aaattaaata aaggcgttaa
     3721 agccagttgt actatagcca cagcaaaata tagtggtatc agaggaaatg acttaaaagt
     3781 aacagttaca acaaatatag atgataatgc taagtttgat gttgtaacac ttttagataa
     3841 taagaaggta gatactcaaa tagcaaaggt tattacagac ttacaagaca atgactatat
     3901 cacttggaag aaggatgcaa cactagaagc aagtgcagga cttgtattta ctggtggaac
     3961 taatggcgaa gctgtgacag gagcagagta ccaagctttc ttggataaaa tagaaagcta
     4021 tagctttaat gctttaggat gtttggctac aacaacagaa attaaaagtt tatttgtaga
     4081 atttacaaag agaatgagag ataaggtagg agctaagttt caaacagtac tatataagaa
     4141 aagtgatgca gattatgaag gtgtagtgtc tgtagaaaat aagattaaag atattggatt
     4201 agtagaatct agtttaattt attgggcggc tggagttata gcaggatgcg atataaataa
     4261 atctaatact aataaaaagt atgatggtga gtttgatgtt gatgttaatt atacacaaat
     4321 acaacttgaa gaagctttaa aaactggtaa atttatattc cacaaggtgg gagatgaagt
     4381 tcatgtgtta gaggatataa atacttttgt atcatttaca gatgataaaa atgacgattt
     4441 ttcaagtaac caaagtgtta gagtacttga ccaaattgct aatgatattg caactttatt
     4501 taatgaaaag tatttaggta aagttccgaa tgataaggca ggaagaataa gtttctggaa
     4561 tgatgttgtt aaacaccata aagaattaga gaatataagg gcaatagaag attttaaaac
     4621 tgatgatgtt agtgtagagc ttggaaatga taagaaaact gtcatagtat ctgatgctgt
     4681 taaggtaata aatgctatga gtaagcttta tatgactgtt tcagttaatt agagaggaga
     4741 gtgataatat ggctcaaaca ataaatgcta aagatacagt tagtgcaaag aaagctgaat
     4801 gttttataac tatagaaggt aaaagatata attttatgca agctatagat ttagaggcta
     4861 aaatggaaaa aaataaaagt gaagttccaa ttctaggaag aacaacaaag ggaaataaaa
     4921 caactgggag tacaaatact ggaagtgcaa catttcatta taatacttct atttttagag
     4981 aattacttta cagatataaa gaaactggtg aggatattta ttttgacata caagttacaa
     5041 atgaagaccc tacatctgct gtaggaagac agacagtagt acttaaagat tgtaatatgg
     5101 acagtggaat aattactaaa tttgatgctg atggtgagta tttagatgaa gatatggatt
     5161 tcacttttga ggattgggaa ttagtagaaa aatttaattt attggcagga atggagtaaa
     5221 atacacattt ataaattata tatgtgtatt ttttatatga aaaattaaaa taaaaggaga
     5281 ttagaataat atgagtaatt taagtgcttt tttaagtcaa aatgcaataa aggttgataa
     5341 tgtaaaatat gtagcgagta acagattttt agataaagaa gggaaaccag ttgaatggga
     5401 attaaaagtt ttatcatctg aagaagacga agcactaaga agaaagtgta ctaaaagagt
     5461 aaaagtgatt ggtaacaatg gtaagcatac tggacaatat acaagtgaaa ttgactacaa
     5521 tagttatgta gctgaattat gtgtagcatc tacagtattt ccagatttaa aggatgccga
     5581 actccaaaat agttatggag taatgggaga agctcagtta ttaaagacaa tgcttacagc
     5641 aggtgagtat gtcaattata cagtaaaagt gaatgaagtc aatggatttg atacatcttt
     5701 tgaggataaa gtagaagaag caaaaaacta atcagaggtg gcgattttga tgctagcatc
     5761 actcattatt gtattcaaaa attaaagtgg aagccaagtg aatatatgaa tttagaagtt
     5821 aatgagagag cgttagcagc cgcctcaata cttataaaga tagaagatga agaggaagca
     5881 atgaaagaag ctgaaagaga gagaaagagg ggacgaagaa gatagcaaaa taaaaaaata
     5941 aatatagaat aggtaaaata tgtaataatt atatgttata atatttttag caagaagatg
     6001 taatctacaa tttatagagt ggagttcata ctgggataaa acctacttcc taatgaaagg
     6061 aggtgggaag tatgaataac tttttactta atgtaatagc tggcgttatt gctagtttaa
     6121 tattttgctt aatttgtaaa gtatttctaa aagtaaaaag ccactcaact cgtggcaaga
     6181 gtaaaagtgg ctgggaattt gattttaaaa tcaagttcca taagttcaaa tagattcatt
     6241 taattatgaa cttcactcta ccgcaaaata gattgtagtt cttcttgctt ttattatacc
     6301 acaaattaga aaaaatattg tttatataaa ataaaaaata aaaattttta ttaaaaaatt
     6361 gaaaacttga ttataaagca attaatttat aaaatatata taaataagta ggtatttatt
     6421 tacttgaatt tcattgttta tataaaaaaa atggaaaaat atgtaataat tatatgttat
     6481 aataattgta gcaaggataa taatcgaaag tgcgaagggt gattattttc atattaaacg
     6541 ccaaattcca aataaggaag gaggtgaaat tatatgatag gttttttatt aagcatacta
     6601 gctggtgtta tatcagctta tatttatgac aaaataaaaa atcacccaga cgccaataag
     6661 ggtgatttaa aaaaataatt ctttaaatca attttgatgg aaatagctac tcttgtataa
     6721 agtaaattat ttccttgctt ttattatacc acaaattggt acagatattc aaaaataata
     6781 tttttatgat ataataaaaa tgtagagatt ttgcagtgag caatatttgc gataaattga
     6841 agtttaacaa ttggaataca aggtattgag ggtgtgtgat aaatgttatc aattgcacta
     6901 ctcatggttc actgcaaatt tgagagagat gcgtatgtgt aggtattgga aatgccaagt
     6961 ttattttggg gttttagatt aactatatgg aatgtaaatt aaccttttta ttgttgttgt
     7021 tattcttatt gttattcgtt ttagattaac tatatggaat gtaaatgttg taagaagtat
     7081 cattctattt tttaatcttt ctgttttaga ttaactatat ggaatgtaaa tagtacatat
     7141 aatgagtctt taacatcagt tatgaaaggt tttagattaa ctatatggaa tgtaaatgat
     7201 tgtactttag cgtctgcact agctttgtct atcgttttag attaactata tggaatgtaa
     7261 attattttac agatgaacaa ttacagttac ttcttgaatg ttttatatta actaagtggt
     7321 atgtaaataa tggaagcaag ataattttta aaggtatgga taattgtttt atattaacta
     7381 tgtggattca aaattaaata gaaaaaagaa agcacttact taaatagtag gtgcttttgt
     7441 tttgctcaaa attggtcggt tgagtaaaat aattagaaaa aattgggata agttattgac
     7501 tttttggaac acaaataata taattatatt atggaacaca aaaagtgagg tgaaacaatg
     7561 agttctaaaa tgggaagacc aaaagttgat aatcctaaaa atattgatgt caaagtaaga
     7621 tttgatgaaa atactcataa aaaattatta gattattgtg agaaagaaaa tcttactaga
     7681 acagaagcaa taagaaaagg agtagactta cttttggagg aagataagta aaaaagtagc
     7741 ccaacgccga ccaaagcata ctggactact taacctagag ttatctctat atgaaatatt
     7801 ctatcatgta aagataactc tttcaagata ataaatcgaa agggtgattt ttgtatgaat
     7861 aatgaactga tgaattttga aaataatgaa ttaggaataa aaataagaac tattaaatat
     7921 gaagatggaa gtataggaat taatgcagag gatacagctg tagggtttgg atggtgtcag
     7981 acacagaata aaaatggtaa gcaatatgta tcaattagat gggaaactat taataaatac
     8041 tgtaaagaat ttggtttcct caacttgttg gggaaagatg agtatatacc tgaatcatta
     8101 ttttatcttt taggtatgaa agctaaaaat gaaatagcag taaaatttca aacatggtta
     8161 gcagtagatg tactaccatc aataagacaa actggtgcat acataactaa caatgctaat
     8221 cccgaaaaac taagagaaaa agcaagtgag attgaaaagt tacaattagc ctataacagc
     8281 acatctatgt taaaagaatt gctagatggt gcaggatttg acaataaatc caaactatta
     8341 acagctaaaa cattatataa aaaggcaggc attgatttac ctatagaaat tgaagaagag
     8401 gaatctttct ttgacacaaa acaaatagca tctaaactga aaatatattc taagagtaat
     8461 aaaccagcac agttggctgt ttgtgaaatt attaaaaaga ttgatttaga agaaaacgaa
     8521 gtcaaaggcg tttgggaaac taatggttct tggactggta ctgtaaataa atatacaaag
     8581 agtgtaatag ataaggttag aaattggata gaggaaaata atagacctgc taagattgca
     8641 ggtgaaaaga agaattatca tgtggtttat aagattgagt aaatttatca gttgtattaa
     8701 ataatttagt ttagtttatt ttagttttga gggggattaa tacaatgtgt gagaatttac
     8761 ttaatgaata taatttaaaa actgatgaag atgtagaata ctttgtaaag tttgctacat
     8821 tattatataa attaaaacag gacaatgaag aaaaatttca agagtatgca gagatattga
     8881 gaggtattct tagggaacaa caagagagag aaaataagta aaataatata gataaagcac
     8941 ttgaatatta catagtttca agtgctttgt ttggtataaa atggtataat agagataaga
     9001 gttatattaa ctatgtggta tgtaaagaat gtataaggca tcttctcaaa ttctgcgttg
     9061 gtcattttat attaactatg tggtatgtaa agtgcgttaa ctgcaataat gctgaactca
     9121 tttcttgatt ttatattaac taagtggtat gtaaatgtta attccttcaa ccttctaata
     9181 gaagatgctt ttaggtttat attaactaag tggtatgtaa atgtttcaac atttgacatg
     9241 tgctgtggag taatgtttat gttttatatt aactatgtgg attcaaaatt aaatagaaaa
     9301 aagaagcact tacttaaata gtaggtgctt ttgttattct ttgctagata aagtaacaag
     9361 ttcattaggt gtacattcaa gaacaagaca aagcttttcg aataaatcta attttataga
     9421 acttgtttca ttgttagcta atttcatcat gttaggataa gctataccta cttctttagc
     9481 taaccaatat ctagttcgac ctttggattc aagtaattta tcaatgttaa aatacatttt
     9541 ttcacctctt aagtatatta tacaacaatt atataatgtt tgcaatatat aatatgcaaa
     9601 caatataatt atataatgtt gacattatat aatgtgtgcg atataatata cttaaggaat
     9661 aaaaaataag agccactcgc ccctaccaag tttgagtaac tcttattgac atatactaca
     9721 tatacattaa ttatagtata tgtcattcct taaaaaaaat caattaagga gtgtgttttt
     9781 atgaacaatt tagtactaat taacaatcaa gaagtgcaag ttaaggaatt taataatcaa
     9841 agagtagtta catttaaaga aattgacaga gtacatgaaa gagtagaagg aacagcaggt
     9901 agaaatttta gagaaaataa gaagcacttt ataaaaaatg aggactattt ttatttagaa
     9961 ggaaaagaat tatcaacaat taaacagaca acgaatttcg ttggcagtaa tgcaagagaa
    10021 ttaatcttat taactgaaac aggttatcta atgttagtaa aatcttttac agatgattta
    10081 gcttggaaag tacaaagaca attggtaaat agttatttta gagttaaaga agaaaagaaa
    10141 gaaatgaaag cattagaaaa attagaaaca gttaatgagt caattaggtt aataactcca
    10201 atttttgatg atttaaacat tgataaaagt atgaaacttc ttgtaactaa gacttttttt
    10261 gaaagagcag gtattgaatt gcctcttgaa gttgaagaaa aagaacattt ttatgataca
    10321 aagcagattg caaaaaaatt aggactttac acaatgtcta ataaaccagc atttatggca
    10381 gttaagcaaa ttataagaaa gcttgatatt aaagaagatg aaatgaaaac agtattagaa
    10441 acgaatggca attggactgg tactgtaaca aaatattcta ataaggttac agaaaaggtc
    10501 aaagtgtggt tgaaagaaaa taataatcct atctcaatca aaggagacaa gaaaaactac
    10561 tatatattgt ataaaaataa ttagatttta gtttttgggg gggtaataca atgtatgaga
    10621 atttacttga tagtatagat attgaaaaga gaaaagaaga atttagaatt aaacttttga
    10681 aaataagaga aacagatata gatatatata tataataaga tagaaagaat agtatataaa
    10741 ctttctgaga aaaaattaga gaaaaataat taaataaata gataaagcac ttggatatta
    10801 tgttgtttca agtgctttat ttggtataaa atggtataat aaaaatatag gaattttgca
    10861 gtgttcgatt tttctactta agtatagttt aacaattgga atacaaggca ttgagaaggt
    10921 ttgataagtg ttatcaattg cactattacc cgctcactgc aaatttgaga aagttatatg
    10981 tgtgtaagtc ttggaaatac acaatttatt ttggggtttt atattaacta tgtggtatgt
    11041 aaatcttttt aaaaaagcac gtcaattaca atactaaaat tgttttatat taactatgtg
    11101 gtatgtaaat ttgaaaactg catgttcttt aacaaaagca tctaattgtt ttatattaac
    11161 tatgtggtat gtaaatgtat tactcccaat tatgaacata ggatatagtc tttgttttat
    11221 attaactatg tggtatgtaa attatagttt gccatatgtt cctggttcgt atgattgggg
    11281 ttttatatta actatgtggt atgtaaataa atttaatatt actggaaaag gagaaatgga
    11341 tatcggtttt atattaacta tgtggtatgt aaattttgtt ataagaatat cgccaccttc
    11401 cttttctggt gttttatatt aactatgtgg tatgtaaatt tttctgcatc ttctactatg
    11461 ttatattctt ctaatggttt tatattaact atgtggtatg taaatgcaca tttaacttca
    11521 agtcttagag tattatctgc aagttttata ttaactatgt ggtatgtaaa tttcgttcaa
    11581 cttttatctt agcttctcct gctacttgtt ttatattaac tatgtggtat gtaaatgtac
    11641 tagaaaatgc actacctgca ttcattccta tacggtttta tattaactat gtggtatgta
    11701 aatgtgctat ttccaacttt tttttcaagt tctgaatact gttttatatt aactatgtgg
    11761 tatgtaaatt agttagtccc atatcgttat ggtactgcat taacgcgttt tatattaact
    11821 aagtggtatg taaatagtgt aaaaggcatt ttttcaaatt gtgcattggt ttggtttata
    11881 ttaactaagt ggtatgtaaa ggctaatgtt tgagtattta aaagcatctg agcaaacaat
    11941 tttatattaa ctatgtggac ttaaaattaa aaataattca aaaacactta caaatgagta
    12001 agtgtttttt taatgaaagg aggtgataat aatgtaaaaa ttttacgtat atagtataat
    12061 agtgctataa aataagtatt atgtgaggtg attgttgtgt tttgttcaaa ttgtggttat
    12121 gagataactg gtgcaggcaa attttgctca aattgcggaa cagctacatt agcagataaa
    12181 gttaacaatg atgatttatt tataaatgtt catggaaaag aattaaatct gactaatatt
    12241 tataaagaaa ctaaaggaga taaaatctta gcaattgata ttgcaatgaa gttactaggg
    12301 ctggacataa aagagtgtaa aaatattata tatccagctt ttaaagaatt aagtgaaaaa
    12361 ataaatatcg aagaggaaaa agagatattg agggaagatg agtataaaca aactaatgta
    12421 cttgaagatg atgttgctcg ttgccctagg tgtggctctg tttcattgtc tgctcataag
    12481 aaaggttttg gcataggaaa agctgtagca ggggctacta tagcaggagg cattggttta
    12541 gtagctggaa atttaggagc aaagaaagtt agagttacat gtttgagctg tggtaaacag
    12601 ttttgggcat aaataataaa cacttactaa tgtaggtgtt tttttatatg gaaatttatg
    12661 aaaggagagt gaggaaatgg ctacaataca aacttcaata aagattttcg acggaatgac
    12721 accagcattt cgtaatatga ctaattctat taatacaaca attaatagtt tagagagatt
    12781 gcaaggcaga ttgaataatc cactcaatgc aggtaatata caagcttctc aacaaagttt
    12841 gaataacata gaaagtattc tcacaaggat agaacagaaa attggaagaa atacaaatga
    12901 acaggaaaac tttaataata aaataagaca aggtagtgaa gcaggttctc tattagtgtc
    12961 taaattaaaa agtattgctg ggatatacat tggaataaaa ggaatagata gtattacaaa
    13021 agtagcagat acaattgcaa gtacaaaagc acgtttaaat ctaatgaatg atggcttaca
    13081 gacaacagac cagcttaata aaatgattta tttgtcagcc caaagtgcaa gagctagtta
    13141 tgcagataca gcagcacaga ttgctaaact tggaatactt gcaggagatg cttttggaag
    13201 ttcagcagag gtgataaagt ttacagaact tatgaataaa gcttttgtaa ttggaggaac
    13261 atcagcaaat gaagctagtg cagcaatgta tcaattaaca caagccatgg gtgcaggaaa
    13321 acttcaaggt gatgagttcc gttccataat ggaaaatgca cctttattag ccactaaaat
    13381 agctgatgca atgggaaaaa ctaaagacca attgaaggaa ttatcaagta gcggagcaat
    13441 aacagcagat gttataagaa atgcactgtt taaagcttct gatgagatag aaaagaaatt
    13501 tgcaagtatg gcaatcactt tttctcaagc tctcacaatg atgaaaaatg atgcttatat
    13561 gatattttct gagactctca gtaagataag tggagctttg caaagtgtac gttttagtga
    13621 gattgttgta tctatgcgga atgttatgat tgcaatatct tcaaacattt atgatacatt
    13681 aaatattata aaaaatatat taaatagtga ttttttttca gattttgtta gcaatgttac
    13741 attaggagct atactaatta tcaatggact gggatgggtt actaatgcaa cactaaatgt
    13801 tgctaatgtc tttgctcaaa attggtcgat tattgctcct attatttatg gagtgatagc
    13861 agcaattgcg atatataaag gagtattact tgcaagtaca attgccacta cggtagcatc
    13921 ttttgtaaat tcattgtatg cagtagcagc gtataaatct tgtgcagctt tagcagcaca
    13981 agaatttgcg atatttggaa aaatatctgc acaaacgatg gaagctttgg taacagcaca
    14041 agcaacagca gcacaatggg gttttaatgc agcattatta tcctgtccaa ttttttggat
    14101 aatagcaggt attatagcat ttgtagtagt agtttttgtt gcagtagcag cagtaaacaa
    14161 attctcagga acaagtctga ctgtactagg agcaattgta ggtgcagtat ttgcagcagt
    14221 agcatttata caaaacataa tgatatggct atttaataga tgcgtagatg taaatgaagg
    14281 gattgcaaat ggatggaatc aatgtgtata tctaatgaaa caagctattg caaaaggtgt
    14341 aatctttata attgagaaaa tggcatcatt aaatgatgct gtaaataatg ctggaaatgc
    14401 acttgggaaa gctttcatag atggggcaaa tatcgcaata cgaggtgtaa acaaattaat
    14461 tgacctaata aataaaatac cagggataaa tattggtaaa gttggagaag caacatttac
    14521 gcctgtcaag gcagataata gttacatcaa acaacagatt gacagtttaa ataaatgggt
    14581 aggagatgca ccagaaaaaa taaaattgga tagaatggga tataaagata ttggagcaga
    14641 atttcaaaaa ggaaatgcac ttggaactaa atggcaaaat gctataactg ataaatttaa
    14701 agatactttt gacattaata agatgctaga agatgcaaag aaaaaattag gattagacga
    14761 tttgtggaat aaacaaaatc ctttaaacaa ccttggtgga tttggtggag atttaggaaa
    14821 aaatgtaaaa gacacagcag gaaacacagc caaaatggct aaaacaatgg ataaaagtca
    14881 agaagacctt aaatacttaa gagacattgc agaacaagaa acaataaaca gattcacagg
    14941 agtaaacata aaaattgata tgaacaatac taacaatata agtaaagaca cggatgtgga
    15001 tggtatagta aatgttttaa cagaaaaact gaatgatgct atgattgtat cagcagaagg
    15061 aatagtttag aaaggaggga tataaatggc ttatgacttt tatttagatg gagtacaatt
    15121 accaatacct ccgccaaagt tagagattaa agttacaaat aaaaacaaga tagttgattt
    15181 gataaatact ggagaagtaa acatactaaa aaaagaagga ttatctgaaa taagttttga
    15241 agcagaattt acacataata agttgccatt ctatcgtgga gcttttaggg atgttcaatt
    15301 ctttttaagt aaactggaac tattaaaaac tgattgtaag ccatttcaat ttattgtatc
    15361 gagggaatta ggtaataaag tactatttaa cactaatata aaagtatctc ttgaagagta
    15421 tgctatttca gaagatgcag aaaatggttc agatacaaaa gttgcaataa agttaaagca
    15481 atatagagat tactcaacta aaaagttagt tcttgcccct cctaaaaatg agactggtag
    15541 acctaatgta aagatagagc caaaacgagt tgattcagtc aatgccacaa acactaaaac
    15601 atatacagta aaagcagggg atagcctttg gtcaatttgt cagaagcaac ttggtaatgg
    15661 ttcgttatac aagaaagtat atgagttaaa taaaacaatg atggataaag ctaacaaggg
    15721 taaaaaagta cctaaatata ccatctataa agggcaggtg ttgaggcttg tctgatgatt
    15781 tagttctggc gaatgataga gatataaggc tagttattgc acattgggaa gatttctacg
    15841 aacctgctgt cattgatggt atcacatggg agatagaaag aagaggttca ccttcaaagt
    15901 tagagtttac tatagcaatg gatgatatat tagagttttg cgaaggtaat tctgtaagga
    15961 tatattataa gggaattggc atattttatg gatatatatt tcagaagaaa agagataaag
    16021 aaaatcacat taaaatagtt gcttatgacc agttgagata ttttaaaaat aaagatactt
    16081 atgtatatag taataaaaca gcaagtgaac ttgtaaagat gttggctaaa gattttaatt
    16141 taaaatacaa tgtcatagaa gatacaaaat ataaaatatc gagagttgaa gaaaataaaa
    16201 cactctttga tatggtctta actgcactag atgatactct aagagagaaa aaagaaatgt
    16261 atgtgttata tgatgatttt ggaagaataa cattaaagaa tgttgcatca atgaaattag
    16321 atactgttat gaacaatgat gtaatagaag actttgacta taattcatca atagatagtg
    16381 atacttacac aaagattaaa cttgtgagag ataatgaaga aacaggaaaa agagatgtgt
    16441 atattgctca agactcaacg catatgagga gttggggaat acttcaaatg tttgatacag
    16501 tagacaaaaa catgagtgaa gcagagataa aacaaaagtg tgatatactt ctaaaactat
    16561 ataataagaa aactaagtca ttaagtttaa aaaatgtact tggagatatt agagtgagag
    16621 caggttgttt agtacctgtt tttttaaatc taggagatat taaacttcaa aattatatgc
    16681 tagttgagaa agtaaaacat acttttgaaa ataacagtca ttttatggat ttgactcttg
    16741 ttgatggaga tgaatttgct tcttattctt caagctcata ttcaagtgga aatactaaca
    16801 ataaggatga aaagaaaaat ggtcctgcac aaagtattac gaaaaaaaat acaggtaaaa
    16861 aagttcctgc tatatttact gcatattatc cagggaacaa tgcaatggaa ggcggaaaaa
    16921 cagattgcaa tggaaagcca cttgatgtaa aatcaagaac tgttgctggt ccaatgaatc
    16981 gagaaggagt taagaaaact tggtatactg atgattttct aaagaaacat ccagtttttg
    17041 aatatggaga taaagtaaaa attatacttc ctggtactgc ctatgacaac aaagtatata
    17101 cagttaaaga taatggagga agaatatatg ttgaaacaaa cggaacatat catatagatg
    17161 tactattagc taatgctagt gaatgtaaaa aatttggtag aaagaatggc tatataatta
    17221 taggtggaga tgaagaacaa acatatcaag ttgaaggtaa taaccaaagt agtacaaata
    17281 ataactctaa agaagataaa ttaattagta tagcaaaaag taaactgggt tgtaattatg
    17341 tgtatggagc agaaggtcct aataattttg attgcagtgg gtttactcaa tggtgttata
    17401 aacaaatagg tataaaaatt cctcgtactg cttctgcaca aagtaaagca ggaaaagcag
    17461 tagatttaaa agatagaagc aagtggaaag caggagactt attatgtaga attggaggag
    17521 gaagtagtaa tcatgttgta atgtatattg gaaacaatca aataattcat tcaccacaaa
    17581 caggagatgt ggtaaaaata gagtctgtta attcttatag aaaaggaaaa gcatacacac
    17641 atgtgagaag atttatataa gtgaggtggc aatatgagcc aagatttatt acagataata
    17701 aaaaaagctg caatggatgc agtagaaaca agcaacccaa tgagggttgt atttggaaca
    17761 atagaaagta ttagtcctct aagagttaag atagaacaaa aactatctat tggtgaaatt
    17821 tttctaatac aaacagatac atttaaaaga tatacagata aaaaaatagg agataaatta
    17881 gtcttaattc gtatgcaagg agggcaacaa tacttgattt tagataggat gtgataaagt
    17941 gttaccaagt gataatttag attatgatat tgaagatgta tcaataatta attttgatgt
    18001 aagacaagag ccaagtaaga catttaaact tcatatagaa aagtctaaga ttgatggtat
    18061 ttgtgatgat gtagaagcat taaaacagac catctttttg attttaaaca cagagagata
    18121 ccaacatcta atatatagtt ggaattatgg agtcgagttg aacgacctta ttggagagcc
    18181 tatatccttt gtaataccag agttagagag aagaatcaaa gaagcactaa ttcaagatga
    18241 tagggttgaa aatgtagata attttgagtt tgaaaatata aagggtaaag tacaatgtaa
    18301 attttcagtt catacaaaat atggaaatat aaaagcagag aaggtggtga gtgtataatt
    18361 gtttgagtta atgacatttg aaaatataat taaaagaatg ttagatagtg tacctaacac
    18421 acttgataag agagaaggtt ctataatata caatgccttg gcaccagttg cagtggagct
    18481 tacagaaaca tatattgcta tggatgaatt actagaccaa acattcgtag atactgctag
    18541 ttattactat ttagagaaga gatgtaaaga gcgaggaatt acacctttac cagccactaa
    18601 tacaattgct aaaggagttt ttaacataga tattccactt gattctaggt ttaatctagg
    18661 agaatacaat tatattgcaa ttgagagaat atctgaaaaa acatataaaa tgaaatgtga
    18721 aactgctgga cctatatttg agttaggaaa actaatacct attgaatata tagatggtct
    18781 tgaaactgct gaactaactg aaatcttgat aaatggagag gatgaagagt cagaagatag
    18841 tttaagacaa agatattatg atagcctaaa ttcacagagc tttggtggga atatacaaaa
//
LOCUS       DAGQVA010000078        18504 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.078, whole genome shotgun sequence.
ACCESSION   DAGQVA010000078 DAGQVA010000000
VERSION     DAGQVA010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.078"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(505..1377)
                     /locus_tag="MIV85_003018"
     CDS             complement(505..1377)
                     /locus_tag="MIV85_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2962342.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1771..2349)
                     /locus_tag="MIV85_003019"
     CDS             complement(1771..2349)
                     /locus_tag="MIV85_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBY2962343.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2407..3123)
                     /locus_tag="MIV85_003020"
     CDS             complement(2407..3123)
                     /locus_tag="MIV85_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBY2962344.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3314..4399
                     /locus_tag="MIV85_003021"
     CDS             3314..4399
                     /locus_tag="MIV85_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBY2962345.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4554..5213)
                     /locus_tag="MIV85_003022"
     CDS             complement(4554..5213)
                     /locus_tag="MIV85_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962346.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNSNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5430..6722)
                     /gene="lysA"
                     /locus_tag="MIV85_003023"
     CDS             complement(5430..6722)
                     /gene="lysA"
                     /locus_tag="MIV85_003023"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBY2962347.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYVEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6740..7933)
                     /locus_tag="MIV85_003024"
     CDS             complement(6740..7933)
                     /locus_tag="MIV85_003024"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBY2962348.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(8294..8911)
                     /locus_tag="MIV85_003025"
     CDS             complement(8294..8911)
                     /locus_tag="MIV85_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962349.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9081..10781)
                     /locus_tag="MIV85_003026"
     CDS             complement(9081..10781)
                     /locus_tag="MIV85_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962350.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(11178..11741)
                     /locus_tag="MIV85_003027"
     CDS             complement(11178..11741)
                     /locus_tag="MIV85_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962351.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11900..12613)
                     /locus_tag="MIV85_003028"
     CDS             complement(11900..12613)
                     /locus_tag="MIV85_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBY2962352.1"
                     /translation="MGKVAKILLSLIVIVLVLVGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12905..14569
                     /locus_tag="MIV85_003029"
     CDS             12905..14569
                     /locus_tag="MIV85_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBY2962353.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14676..15575)
                     /locus_tag="MIV85_003030"
     CDS             complement(14676..15575)
                     /locus_tag="MIV85_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBY2962354.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15602..16240)
                     /locus_tag="MIV85_003031"
     CDS             complement(15602..16240)
                     /locus_tag="MIV85_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBY2962355.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16581..17579)
                     /locus_tag="MIV85_003032"
     CDS             complement(16581..17579)
                     /locus_tag="MIV85_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBY2962356.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17677..18252)
                     /locus_tag="MIV85_003033"
     CDS             complement(17677..18252)
                     /locus_tag="MIV85_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962357.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
BASE COUNT         5998 a         3067 c         1947 g         7492 t
ORIGIN      
        1 ttataaaaac tttattttat ttttataaag tattatattt ctaaaaaagt ttccctttcc
       61 ccaaaaatgg ctacttaaaa aatcaagatt tcatacctaa ctactaattc tatgattttt
      121 aaatttttca acttctttgt caaagttaaa ataaaatact aaaagacaca tattatagtg
      181 aacaaaaaag atagaaatac atattttaat agaattttaa taagatatta tatacttaaa
      241 tacaaataaa attaatttta taattgttaa ttaaggaaat gatattgttt agagaaataa
      301 aaaaagcact ctccatgaag ggaaatgctt tctttaataa attagttgat gtagtaaaga
      361 tatattcaga atacatcttt atgttttgag tctcgaaata tttatttgta ttatttaaac
      421 gaaaatttat tttttaagtg ataatctagt atttattaat aaggctatga ttctcaattt
      481 catagcctta ttaatacaca aactttactc atacacagaa tatcttttcc aaatttgctc
      541 taaatcatca aaatgctgtt taatatcttc tttttccttc atcccaacag atatagcaag
      601 agcatttgaa atactaagag ctggaactag agaatctaca aatgaagcca tattactctt
      661 aactagaaga gtgttatctg caagtgatgc tactggcgca aataagctat ctgttaatga
      721 tattacatgg gctccttttt ctttagcata attgacaatt tgataagatt tcttagaata
      781 acgagggaaa ctaatagcaa ctattacatc ttcttcattt attcttacaa tctgctcaaa
      841 agcatctccc atatccattc taattatatg aacattgtca agtattatat ctaagtaaaa
      901 acctaaatat tgagctacta caaaagaact cctcattcca agtatatata tttttctcgc
      961 tcttaaaagt ttgttagaag cttctttaaa cgctctctcg tcaatttctt ctagtgtaga
     1021 ccttatatta tctatatcac tttttaaaac tttgtttagt attgcaaaat catcggaata
     1081 atcatgtgcc atttcaactc tttgtactgt agttagttta ttttttatga gttcttgaag
     1141 tgcagcttgt aatttaggat atccactata acctaatgca tttgcaaatc ttacaactgt
     1201 agactcactt actcctacag tttcacccaa tttacatgca gtcataaatg caactttatc
     1261 ataattattt aaaatgtatt gtgctataag tttttgaccc ttactcaatc tcgtatattg
     1321 agattgtata tttgatatca aatgtttact gtccttcatt tcatttgttt cttccatttt
     1381 tttctccttt tagttatata aactattttg ttttattaac actgtctttt tctctaaaaa
     1441 ttttattttt tatctcaatt tcatcttagt ttttatcata gcttcttaaa ctcataaaat
     1501 tctaactttt ctgtacctta tacttcacat agtattttcg attaaattta ttataccatc
     1561 tttccttgca ttttttaata tttatccaat atttctttta aatttttcaa tttttactca
     1621 tttaaaagtt atctatctta ttttgcatat ttagatgtat attttgtttt gagaataaac
     1681 tgttgtatac ttattattta aagtattttt aataggtcac actatatata ttaactctta
     1741 atacaatctt gtcaagtttt ttagtattta ttatgctttt ttcttttcaa ttaaaatcaa
     1801 ttgtggtggg ttattgactt gatttaaaaa cttagattct aaaacattaa attcatcttg
     1861 atttaaatta ttgacaaggt tatatatgca atctttttct tcttgacctc catcatgccc
     1921 tgtatatatg gcaatgctta ttactccatt ttcttttaac atttctaaac ttaactttat
     1981 agcctttaaa gttgtatctg gtttggttat aattgaatgt ttcgctcttg gaagataacc
     2041 caaattaaat aaaacacatg aaacttcttc ttttatatat tgattcattt tttcatgccc
     2101 atcaaatatc aattttactc tatctgtata tccttctttc tctagtttct ttcttgtaga
     2161 ctttattgct tcttcttgta tatcaaaagc atatacaaag cccttttctc caaccttctc
     2221 agctagatac cttgtatcat acccatttcc catagtagca tcaattacta tgtcaccttc
     2281 atttataata ttttctaaat aaaatttatt tatatctgta attttagtta aatactttgc
     2341 atatgccata atactatttc tccctactat taactttatt tcattttttc tcaatttatt
     2401 tttatcttat tttattgatt ttaaatattt tatttcatct tctgttaggt atctatattc
     2461 tccaactttg gtgtctttta atactatttt ccccacagaa atccttctta aatttaaaac
     2521 tggatgattt atagctttgc acatttttct tacttgtcta tttctaccct catgtatagt
     2581 tatttcacac actgaataat ttttttcttt attttcttta gttaccctta ttttggcagg
     2641 tgccgttgtg taatcttcta tttttagtcc tgtttcgaat tgtcttatct catcatcact
     2701 tataattccc ttcacacttg ccacatacat tttatcaatt tcatgctttg gatgggtaag
     2761 cttatatgtt aaatcgccat cattagtaag tattaataaa ccactagttt cataatctaa
     2821 tctccctatt ggatatactc tttcccttac atctttaagt atgtctatta cactgggtct
     2881 attgaattgg tcttttactg tagttatata tccctctggt ttatttaata ctatatatat
     2941 ataattttca cttggtttta cttttttatt atcaaattct actatgtctt tttcttcatc
     3001 aatattaaaa gataactctt ttactacact tccatttacc tttattcttc ctccaagaat
     3061 tatttcttct gcttttcttc ttgatgctat tccacaagaa gctatatact tattaattct
     3121 catacttaat ccttccttat cttaaattat gtgtgtttaa tatttttatc aatgttaatt
     3181 ttgctacatt attatactat actagacctt aattaaaaac aagcaaaaaa attatttaat
     3241 tttcctaaat aattgtaatt tcttttcaca tactattaat atgtaatagc tgactaaaca
     3301 ctattttaag gaagtgatta ttatttcaaa ggaaaatata aaatattatt taatagtcgt
     3361 gtttattgga attttatttt ttaaatttat taatactcca tcagacttta tatctagtat
     3421 tgaaggattc ttaaagtttt ttagcccatt tttattagct attttacttg ctttactttt
     3481 aaatccactt gtgatgcttt ttgagataaa attcaaagca catagacttt tagccatttt
     3541 tttatcttat atatttatag gttttatttt agcctttgcc attaggttat taattccatc
     3601 aatagctaat acattaaata gattgataaa tgaaatgcct atgtatactg attatataga
     3661 tagttttata gaaaaaaata tgtcaaacat atattttcta aaaactttaa ttcctcatat
     3721 acaacatagt ttagataatt tattaaaaga agcaagtaat tttgttggta aaattcctaa
     3781 aaacttctta atctatacac ttagtatatc ttctatgcta tttaatatga caatgggatt
     3841 tatactatct atatacatta tatatgacaa agaaaaaatt gcattgggat ttaagagatt
     3901 tctatattct tctactgcta gaaacaaggc agataacatt atagaatttt ttaggactac
     3961 tcatgatatt ttctatgatt atttacttgg tagaatatta gactctctta ttattggtat
     4021 aattgcattt ttaggatttc aatttgttat cagaatagaa aatgctttat ttttagcttc
     4081 aataatattc ttaggtaata taattcccta ttttggtcct tttattggtg caatccctcc
     4141 aatagccatg actatattat atagtccaca aaaaactata tgggtcattg catttctatt
     4201 tatattgcaa caattagatg gaaattttat agaaccaaaa gttatgggta atcaagttgg
     4261 tataggagct atatgggtaa tatctgctat tttggtggga caatctctat ttggtttcat
     4321 aggagttttt ctttcagtac caatagctgc tgttgtaaaa acttatgttg ataaatatat
     4381 agataatcgt ttacaatagc ttatctctac tgtgacttta atttttagtt taaaatttaa
     4441 ctgttattta ttaaattatt tctcaaaaaa tatctcttag taagaaaaaa ttgctaagag
     4501 atatttttta taatatataa tttgttcatt aaatttatgc atatatttta tacttattga
     4561 ttatttgagt tttgagaatt tccaccacta tctgaaccac cagtagtatc ttgtggagtt
     4621 ggtgctggtg ttggattact attatttggc ttttcttgat tttgagaaga actgttacta
     4681 ttgtcagact tattactatc tgatttttta tcattatttt tagaactaga tttattattt
     4741 ttactacttc cactataaga agatttcctt gcatctgatt caactctata cctatcttct
     4801 ccagccgtat cttttgcctt tttctttctt tgttcctctg cttcgttttg ttctttttct
     4861 aatttagtta actcttcttt ctttttagtt gcctcttctt taataacaga ggaaccattt
     4921 ttgattttct ctataagttt aagttccttg attgcaccct cataattttt taattcttca
     4981 aactccgtca tatttgacat tctcatagct tgcatataca tagctcttgc attctcatta
     5041 gtactatctt cttccagtgc agaggataat gattccatag cttttttata gttatgtttt
     5101 tctaaatatg tttttccttg ctctactaaa tttatttcat cttttttatt aaatgaacat
     5161 cctacaagaa atatagataa tatcgatatt aataaaatta ctcttcctct cattaaatcc
     5221 ctccttgtca tatactttaa attttatcat aattataaag tttttaaaat attttatatt
     5281 tattacaaga aatttgttag taaaacaaaa aataagcaga tatgctacga acgatacaat
     5341 aaaccaaaaa ttaatttaga gatacatatc ctagcaaatc tgctcataat aaactttaat
     5401 atttaatttt tattatatac ttctccattt tatatctcta aagctaataa gtcctcatag
     5461 ctttgtctct tacaaattat cttatcattt ccatcaaata ctgatactac tgctgctctt
     5521 ggtattttat tataatttga agacattgaa tatccatatg caccagttga tgttgttata
     5581 agtatatctc cacttttaat atccattatg tttatatctc caattaatat atctccactc
     5641 tcacaacatt ttccagctat tgttacatga ttcatagcct catgattaat tttattcaca
     5701 atactacact cataactagc ttggtacaac gaaggtctta cattatctgt catacctcca
     5761 tctacactta cataaaccct aacatctttt atatctttta tagaacctac tgtatacaat
     5821 gtacttcctg catttgcaac tattgacctt cctggttcta ttaccaatgt aggtacttct
     5881 attccaagct ctttacatga agtttctgct ttagtgatta tggtttcaca aaactctttt
     5941 atagttttag gtttatctcc ttcgctataa taaacgccaa ctcctccacc taggtcaatt
     6001 tctgttagtt gtatgttgaa tttttctttt atttctttta ccaagttcat cattatatcc
     6061 actgtatcta tgtatggttc tacatcaaat atttgtgaac ctatatgagc gtgaagaccc
     6121 acaagtttaa tatttttata ttcacttaat ttttctattg ctctaaataa atctccattt
     6181 actaaagcaa atccaaattt agaatctatc tgtccagttt ttatataatc atgtgtatga
     6241 gcttctatac caggagttat tctaaagtat atctcttgag ttttaccttt atcttcacat
     6301 aatgcttcaa gcaaatctaa ttcataaaaa ttatccacca caaatttacc tacacctaaa
     6361 tctaatccca tgtttatttc ttctttagtc ttattgtttc catgaaagaa aactttttcc
     6421 ataggaaaat ttgatttata agctgtatat aactcgcctc ctgaaactac atctaaacac
     6481 atttgttctt catttataag attacacatg taaagaggta aaaaagcttt ccctgcataa
     6541 gcaaccttat tttttccctc tctagcctta aaatattcta catattctct acaattttgt
     6601 ctaactaaag cttcatcaaa tacataaagt ggagtttgat attttttact aagttctaaa
     6661 caactcactc ctccaatata taattcatca ttatttacag tcatagttcc atgaagtttc
     6721 ataatagcct ccccaaattt tatatattaa atacttctgc tattttttct atagctactt
     6781 gcttatcatc agaatttata gcacaagtta tacgaatctc tgatgtagtt ataagtttta
     6841 tcattatacc attttcattg aatatcttaa atactttagc agcaactcca gaagtatttt
     6901 tcataccaag acctactaaa gaaaatttag tgatattatt atcaatcact acatgttctt
     6961 catctgtata tttagatact atctttttac attctcccaa ctcttctttt ggaactgtaa
     7021 atgatacact tatcttatct aaaataggtg cagtttggct tatcatatct acacttatac
     7081 ctatagttgc tatatcttca aataagctag atatattttc agctttaaaa tcttttattg
     7141 ttatagaact gtcatcatca ctagtagcta atcctgttat tactttatcc tctaatttca
     7201 tgtcttttcc ccctcttata tatgttcctt tttctgtacc acatgtacgt ccgacataga
     7261 tttcaacacc atatttttgt gcaagctcta tacttcttga atgcattact tgtgctccta
     7321 aactcgctaa ctcaagcatt tcttcatatt caatctcatc aagtttacta gcctttgaat
     7381 attttcttgg gtctgtaaaa taaattccat caacatctgt atatatctca cattttccat
     7441 ttaatttaac cgcaagagct acagcagatg tatctgaacc acctcttcca agagtggtta
     7501 catcaccatc ttcgttgatt ccctgaaatc cagttactat cacgacattt ccttcatcta
     7561 aactattttt aattctgttt acgtttatat catcaatttg agactttcca tgaagaccac
     7621 tcgtttttat atttaactgg taagcattat aacttatagc tttacatcca agtgcattta
     7681 atgctattga taataaagat gctgaaatca tttcaccagt agacattaaa gcatctaatt
     7741 ccctcttact aggttcatta ctcaattcct ttgctaaagt tatatattca tcagtggatt
     7801 ttcccatggc agacacaact attaccattt gtggattttc ttttcttcgt tctattatat
     7861 tttctgctat tgattttatt ttttcagtat ctgctactga acttccacca tatttttgaa
     7921 caattatact catgctttct ccccctcaag ctaaattttg ataaataaaa acgcccaaag
     7981 gtatactttg gacgtgtaaa tttcatagac caagtaacct tgtagctcac cactttaaaa
     8041 gtgacagcct tatgcatatt ctgcataagt ccagaaaatt tgtccgtcaa caaaatttct
     8101 tcggctatat accctttcat caattatcaa cgcttaccag ctcctattga atactattga
     8161 atacagctac ctctacccta ggctcattat ttttaattaa tttattaata tagttttatc
     8221 atattctata taatattgca acaattattt tacaaaatgt ggcaaatcga tagttttctt
     8281 ttctaaagtt agcttatata caattaaata gtttatttaa tcctaaatct ataaaattta
     8341 tgctatactc attatcatat ctctctaaat catttaattc ggatagatta tctggtgtaa
     8401 ctaccaaaac gtttggtact ttaaaaaatg gaattgtaga tttatctatt tttttagaaa
     8461 gattttcgta tttagaaatg tctatttcat tatttaagtc aacatcaact aaaacttgct
     8521 ttatattacc aaattggtct gtatattcaa taaataaatc gtatttcaca tcatctacac
     8581 taacatttcg gtaaaatctt tttacatcac aacctgcagt attgattcta acaactaatt
     8641 ctgatcctac tagagccttt attaaatcat ctcccttaaa aagtttacta ccgtttaaat
     8701 agtatacata agagaggtct ttataattat aataatccac atcacaagga tattttttta
     8761 gtgtatattc actacacatt tttctcaaag tttttttaaa atttttttta ttgtatcttt
     8821 tttggtctcc ataaattttt ctaaattgag actctgtaac acatctaacc ctgctaatta
     8881 aaagtaatat ctctttttcc atattcgtca tagtacattc tccttgaagt attatttgca
     8941 aagttgtact aatattatat taattttatg acattaaatt tacaaagaat taaaataaaa
     9001 tagctaattt ttatagaatt aaattctata aaaattagct atcactatgt taaatactat
     9061 tatcaatctt tttatttaaa ttatacatta ccttgatttt cagaatcttt ggaatctgta
     9121 ttttcatcag ttcctgtttt ttcttttgct tttttatctt caaagtttgc aatatttagg
     9181 ttatcaaatt ctgacatttc tattacacca gattcttctt ttgaatacga tattttgact
     9241 ttatcaccaa cctgagtcaa tggcaattcg ctagatactt ttgaagtagc cctaaatatt
     9301 atatctttat ttgaatctaa agttacataa taattagtgt taccacctcg cacatctggg
     9361 cttattcttg tcactgtgcc ttctaatacc tcatctttta aatcattatc aagttttaaa
     9421 tcattaccct tagattctaa tgcatcctta tagtttctta atgcttcatt cttatcttca
     9481 cctattccaa gtacattata atcttcaaca gatacaaatg caactctctt aacaagacca
     9541 gccttatctt ttaatgatga tacatatgtt ggctgaccca atatattata cattacaggg
     9601 aacgtcgctt cataattttt ttcttgaaca ttaccttcag ctgatttcat tgcagccgtt
     9661 tcagtagctc ctggttgttt atataatcta gcttcttttg ttctagaatc aactaacata
     9721 aatccaattg tagattcatc tccacctgaa gatgttatac ctgtatacca ataagacctg
     9781 ttatcattgc cataaactag tgatgtacct tctgttggta ctaaaactcc cttttctgat
     9841 ataacagagt ttaaaaatcc attaacataa acaccccagt ctttaatttg gtctgttaca
     9901 aagctttgtg gttgtattct atccacccat ttaggcgtgt ttttaacatc ataaacattt
     9961 atttttccag tttctgcatc aacagtggct attcctgttg catttgctcc tccatagcca
    10021 attttatgtt catataaact tacaacccaa taaggtcttc cttcatcatt tatttcaaga
    10081 gtgaaatctg tcataccaac atttacaata ccatgtatgt ataaatgtct ttgtaaatcc
    10141 tgatgtaagt aggcttctgg ttggtaaact atctttattg gctttccatc tatttcttga
    10201 actaattgga cgtcttgagg attactagct gatactttta cataaccact tgtaccactt
    10261 agagatgtta tccatttaat tatgtctctg tgaacaagag gcgctaccca gtacaactct
    10321 ccatctacat tttgtatatg aaattttcct aatttggata cactccctat tgcaggaact
    10381 tctccaagct ttttgtcacc taatttcatt gccatatctt catctacaag acgaatgtca
    10441 tttacactga cagggctaat gtcatcagta aatttacttt cagttacttt tcccaatagt
    10501 tctctatatg attttgcatg aagtacaggt gtagaagtta taaagggaac tactacaata
    10561 tacacaagca aagctattgc tattgaaaaa ttatatttag ccattttaga tgctctttca
    10621 tttctatcta acatcatatc tagtattcct gctacaacaa agaaaattat tcctactgaa
    10681 aataaagatg taaaatctaa tcttagtaca ggtaatttaa taaatgcata aattattaca
    10741 attattaatg caactccata tgttttaaga tatcgtttca tttaatactc ctctctaaaa
    10801 aatgttatta ttactattat atccatatat ttacaaaaaa taaatattta tcatatttat
    10861 tatatattaa gatatcttta tatatttata gttctgctta ttcaactata tttaacatta
    10921 tacgtgtatg tataaatact ttttatacac tgtttgtact atccatcccg cacctaaagg
    10981 agtgggattt ttgcactatt ctgtattata tatatccaaa aatattataa aaatacaaat
    11041 attagcagaa atttaaaaac tgaagaaagt attctaacta agatttacaa attcttaatc
    11101 ctatcgaagt taaactacta tcttcagcct aattatctag caatattttt ttatatgaaa
    11161 aactctaaat caagttttta aatgtttgcg atttttgata cataagaatg ttgtctagaa
    11221 ttatattctg ataataaacc ttcatactct aaggttaagc cagataaatt ataaaaatca
    11281 tttggcgtta cttcaaatgc ttgtttattt aaaatgtcta tctcactttt ttctaacatg
    11341 tcagcaacaa aatttgaaca tacatattta tattcagatt gtctctgaat attcattagt
    11401 aaatatatta atgccattgt atcgtaatag taatcttctc tataatcact aattaatttt
    11461 atatttttat atagattttc atattgtaaa ttatctactt ctaacgaata taccctacac
    11521 acagtgtttt ttcttatagc atataatcct tgatttatat tttcttcaac aaatcctcca
    11581 ataaatggat tccttggatt tagccttcca aaagaataca ttggttttag attttcattt
    11641 aatgatattg acacatgtgt atacagcttt ttacttatat tccttattaa gtaagataat
    11701 atagttcctg tatatgttgt tacaatatag actttattca tcatttcccc ccaatctagt
    11761 aactaaataa tattatacac ttacaattta atatcataag atattctaac ataataaatg
    11821 tggttttaca aattttgatt ttaaggtact ttaatattat ataatataat aaaaatataa
    11881 atataagttt tctatatttt taaccaacag atgttttctt caaattaatc agatgattta
    11941 gtatatcttg aacctttcca gagtccttta aatatcctaa tgccccattt atttgtgatt
    12001 ttaaatctat ttctacttcc atatccaaat caacatttcc tttttttata gatatatttt
    12061 taagtgttat tggataaaga taactttttt ccaaagtaat cttatttcca ttaacctcaa
    12121 atggaacttt tttattgtag ttacttaata ttttttctag cattttatca cttagtttaa
    12181 attttccaat tttcacattc tcaagactta caactaagtt tccatccttt aaagtaggtc
    12241 tcaattcaag ttcatattga ctatttacca aaccaaatac cttatatggt cctgctacct
    12301 ttattttacc atttttcatt tcaacaaaat tattttcaag ttcattaatt ccatgcttct
    12361 gcatcaatgt atatattaaa tttttaaact cttcctctga aacagatatt tttccaacca
    12421 ttctaagtgg attttttact acctccatag aatttatata tgagcctttt gataaatatt
    12481 cttcatctat gattttatta ttttgtgaac taacatcata tctttctttt ggtgtcaaga
    12541 tatatacaac aattcctaca agtactaaaa caataacaat taaacttaac aaaatctttg
    12601 caacctttcc cataatcgtc tcctttacaa atctgtcatc agatttaaaa taaatttaga
    12661 taactaactt cacataatat tcttaacaat atacatacta taatacagtc ttttaaaaat
    12721 taattcaacc aatctaatgt tttgtaaata aactgtaaaa acatgttttt agtataaaag
    12781 ttaatatttt gcataatact cttaattaca cctttatttt tttctaatct tggattaaaa
    12841 ttaatattat gcaatacagt gtagtgttct gtattataat caaattaaat aggaggtata
    12901 gaatatgtca aatgaaacga actcatctaa ctttataaag aatattatta taaacgactt
    12961 agaaacagga aaacatgaca gtatcataac tcgttttcca cctgagccaa acggatattt
    13021 acatattggt catgcaaaaa gtatatgtct taattttgga ttagctaagg agtttaatgg
    13081 aaaagctaat ttaagatttg atgatacaaa cccattaaaa gaggatgttg aatatgtaga
    13141 gtccataaaa gaagatgtaa agtggttagg atttgattgg aacgagttaa attttgcatc
    13201 taactacttt gatgaaatgt ataagagagc tttaatacta ataaaaaagg gtaaagctta
    13261 tgtatgtgat ttgacacaag aggaaatgag agaatatcgt ggtactctaa ctgaaccagg
    13321 aaaagaaagt cctcatagaa acagaactat tgaagaaaac cttgatttat ttgaaagaat
    13381 gaaaaatggt gaatttaaag atggtgaaaa aacattaaga gccaaaatag atatgtcttc
    13441 tccaaatata aaccttagag acccaattat atatagaata tctcattcaa cacaccataa
    13501 tacaggagat aaatggtgca tatatcctat gtatgctttt gctcatccaa ttgaagatgc
    13561 aattgaagga ataactcact ctatatgtac tttagagttt gaagaccaaa gacctcttta
    13621 tgattggttt gttaaagaat gtgagatgga aaatatacct agacaaatag aatttgctag
    13681 acttaatata aataatactg tcatgagtaa aaggaaatta aaacaacttg tagatgaggg
    13741 tattgttgat ggttgggatg accctcgtgt tcctacaata tccggaatca gacgtaaggg
    13801 atatactgca gaagcattgc gcaatttctg tagtgaaata ggggtatcaa aagttaactc
    13861 tacggtagat agtcaaatgc ttgattattt cctaagagaa aacttacaac caaaggctcc
    13921 tcttactatg ggagttttaa gacctttaaa acttattata actaattacc cagaagataa
    13981 gattgagatg cttgaaatag agaataatgc taaagatgaa tctcaaggaa agagattagt
    14041 tcctttctct agagaattgt atatagaaca agatgatttt atggaagaac ctgttaagaa
    14101 atattttaga tttttcccag gaaatgaagt ccgtttaaaa ggtgcttatt ttgtaaaatg
    14161 tactgatgta attaaggatg aaaatggaaa tgtagttgaa atacatggta cttatgaccc
    14221 tgaaactaag agtggctctg gctttacagg acgtaaggta aaatctacaa tacattgggt
    14281 tgatgctaaa tcagctatcc catgtgaatt tagattattt gaaccattaa ttcttgatga
    14341 tatacctgaa aatgaaggta aacatttctt agaacaaata aatcctaatt cattggaaat
    14401 attacaaggt tttgttgaac ctacacagat aaaagatgct aaaccttttg ataaattcca
    14461 atttgttaga aatggattct ttagtataga taataaatat acaactgatg aaaaatttgt
    14521 atttaataga atagttcctc taaaaagttc ttttaaacca ggtaaataat cttacaatca
    14581 aaaaatgaag acttaaaata taaattactt ctactataaa taaacttagt tagaagtaat
    14641 tttttatttg agtcttcatc atttacttta aatgattaac ttttttcact acagattccc
    14701 atgacttcta ttccatcttt tatgcattct atgttaagag gaaaatctgg tcctttttct
    14761 ccgtcaatat ctgttataag tgaatcttca cattctatat gcaccttttt agttttaaag
    14821 tatagtattt catttccatt atattgatct aaataatcac ctctaagcac acttatcaaa
    14881 actggtattg attttggtat tggcattcct ttaaaaataa ttacatccaa atatccatca
    14941 tctatttcag ccttatatgc tagatttata tttcctgctg ttttgccatt aaaaatcaac
    15001 ataagataca tatctccatc ataatacatt tcctcagaag atacttttat cttaaatttc
    15061 ctcatataca atgcttcttc tattcccttt atataataag aaattcttcc aaatgaattt
    15121 tttaagtctg tgtttatcct ttgtgataca tccgtaaaca taccagcact tgcaacattt
    15181 ataaagtact tattattgac tttccctatg tctattttct ttggttttga atttatgatt
    15241 tcatttatag cttcttttat atcaaatgaa atttgaagag catttgaaaa atcatttgca
    15301 gttcctgtag gcaaaattcc aattggaatt tttatgtcta attctttcat tgcatttact
    15361 actaaatcta cagtaccatc accaccagct atcaatatgt gttcataaga actatcaact
    15421 tccttaaatg cattctttac aggttcttta atagttaatc tatagggtat caataaataa
    15481 tttttttctt gatataattc tatgatagtg tctaaatttg ataatatctt tttttcacct
    15541 gaattaggat tgtatataag ttttactttt ttcattattt ctccttactc attttattct
    15601 tttagtatcc aaaatcttca tttaaaaaaa tcacatgtat tctttctggt gttaattgtc
    15661 tttttataag tgtataacta cagcatattc ttcctggact tgaacagtct atacatatac
    15721 cagtagtctt acatccagta tttgtactta atcttttaca attggctgga gcagctattg
    15781 tttttgttct ttttatagct tcatctacat ctttaactat tttatttact cctgctataa
    15841 ctattacttt atcaggtcca tatatcatag cagcaaccct attcccattc ccatctaaat
    15901 tgtaaagttc tccatcctct gttatcgcat tagtacttgt aaaataagca tctgcagaaa
    15961 atgactttct atatatttct ttcatttctt ctggtttgat atcttttgca tatctatcaa
    16021 gaaaattata tttttctctt ataaaatcaa tcactcctgt ttcaaataag gtcatagaac
    16081 ctccacatcc tactagagaa cctgctttaa ctatttcttc aattttttta agaagctctt
    16141 ctttgttact tactaaatac cctttcatat tattgttttc caaagatttt attgtttttt
    16201 ctattctttt ttcattaagc caatttaaat tttgatccat tttaacttcc cccttatttt
    16261 taatatgtac ttaattattt ataaacttta ttttctttat aagtttattt tagtacatct
    16321 aaaaaaaaat acaatataaa acttaaatag ttttacataa ttttttccaa aataacttac
    16381 tcaatcaaaa aaggaaagta gatgtactat tctactttcc ctatattgta tgtagtatta
    16441 tatattgcct aaaatctata tattaattat atgtttcata ttatatgaat atcacagtta
    16501 attaaaatgt aatactatct tctttttaaa catataaatt gtattattaa atttaatata
    16561 tccaacttca ataaatctta ttaatttgat gaagaagatg ctatagctgc acttgttgct
    16621 gccattacac atgcaatttg aatagcaaca acaatattta aaaatatatt attagttata
    16681 gagcctatat tattctcatt tcgtatcaaa tctgcataaa ttgaagctac aatagcagaa
    16741 ctaatcatta ctctattact ttttcctaaa gaccaatttc caaagccttt ttcttcttta
    16801 agtttatttg aaacattttt tatctcttct attatttcat cttctctata atctaataat
    16861 gaaattgctc ctattattgg atatccataa taattcattt tacaatcatt ttctttaaat
    16921 gcttttttaa gttcaatagt ctttttacat ttgagcatag ttctatcatc actaaataaa
    16981 agaatttggg ataatgcttg taaatcattt cctttataaa aaccattttc atttagaaat
    17041 tcataacatt tttctatgta ttctaaatct tcatctaaat tttttgaatg aattgcaata
    17101 agtgctatat tacaatagtc atcactagaa gttagaaatg gatgtttttt cctcatgtaa
    17161 tcatatatta ttttcatttt tgatatacat gtaagataat ccattttctc tctattttca
    17221 taaactattg atgctgtaag tggtaaatat gtatcgcccc aaaacttttc acttttaagt
    17281 tctttgtata tatctaaaat catcttaaaa ctactttctg gatttgattc aaacgaaagt
    17341 agtgttgcca tataaaacat attatatcct ctaaaattag agaataatcc agtatttttt
    17401 ttaataagct ctattcgttc ttccactaat ctaggactta ttctcttgtt cttaagggta
    17461 aatgcaagtg cacaactatg ttgtatcaat cccatttgcc aagaaccttt aacttcattt
    17521 aatgctttgt aattttctat taataagttt acttttccat ttataaacga ttgttccata
    17581 ttgccctcct agtaatatat ctcattgtac taatagtttt atatttatta tatatatatt
    17641 aaatactaca atcaatacat attacttcaa agaacatcat tcttcaacaa taatgtagcc
    17701 ttttttgtaa tgtcttccca tattattgac tctatcatag tactctgatt cactttcatt
    17761 actccatttg ggcacaaata catctattgc attagaatta ctaaaatatt tactagaccc
    17821 cctatccata acagttttta attttccatc tacaataatc ttagttccaa aacttaagtg
    17881 attgtttgct acaaaaccat cttctaaatc atctcctgta gcagttatcg ctccatatcc
    17941 attttcttga ttaagacttg tgtaataact aacttcaaaa gttataggta ctaacttctt
    18001 tattttaata cctaactgat tttgtagttt ctccttttgt actttcaact tatactcatc
    18061 actattttta taatcttcca taccttgatt atacttggaa ttaaagcttt tacctgactt
    18121 tactatagta tctatattta ctatagattc tttacaatga tctgcatcta tttttgtttc
    18181 tccatttacc aataatggag ttaaacatac actacataca acacatgtaa tcaatgcttc
    18241 tttaagcttc ataaattccc cccttattat tttgatatat tagcatattt aatattatat
    18301 gtctacattt agatttaaat accacaccca tttgctttaa gaagttgtct tatatttaat
    18361 tcaccttaaa cacttataaa tcctctatct tagaatcata tagaataaag cttttatctt
    18421 taaatatttt ttattaatct tttaaaatct aaaactactt tatctaattt tctctttttt
    18481 agaatttaag aattaaaatt ctat
//
LOCUS       DAGQVA010000079        18433 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.079, whole genome shotgun sequence.
ACCESSION   DAGQVA010000079 DAGQVA010000000
VERSION     DAGQVA010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.079"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            17..1354
                     /locus_tag="MIV85_003034"
     CDS             17..1354
                     /locus_tag="MIV85_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2962358.1"
                     /translation="MNENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSKGVGELA
                     LAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSIIILSII
                     ILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKTDGFPIL
                     ATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRKNSTLNF
                     SKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSVINYINT
                     LVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICMAFSGPI
                     VSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVISLGRGL
                     VIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKVA"
     gene            complement(1472..2140)
                     /locus_tag="MIV85_003035"
     CDS             complement(1472..2140)
                     /locus_tag="MIV85_003035"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBY2962359.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(2207..2635)
                     /locus_tag="MIV85_003036"
     CDS             complement(2207..2635)
                     /locus_tag="MIV85_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBY2962360.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            2742..3335
                     /locus_tag="MIV85_003037"
     CDS             2742..3335
                     /locus_tag="MIV85_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBY2962361.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            3454..4389
                     /locus_tag="MIV85_003038"
     CDS             3454..4389
                     /locus_tag="MIV85_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBY2962362.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(4660..5604)
                     /locus_tag="MIV85_003039"
     CDS             complement(4660..5604)
                     /locus_tag="MIV85_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBY2962363.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            5922..7352
                     /locus_tag="MIV85_003040"
     CDS             5922..7352
                     /locus_tag="MIV85_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2962364.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            7552..8136
                     /locus_tag="MIV85_003041"
     CDS             7552..8136
                     /locus_tag="MIV85_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBY2962365.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(8240..9019)
                     /locus_tag="MIV85_003042"
     CDS             complement(8240..9019)
                     /locus_tag="MIV85_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBY2962366.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(9077..10333)
                     /locus_tag="MIV85_003043"
     CDS             complement(9077..10333)
                     /locus_tag="MIV85_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBY2962367.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            10591..11490
                     /locus_tag="MIV85_003044"
     CDS             10591..11490
                     /locus_tag="MIV85_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBY2962368.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            11514..12962
                     /gene="ddlR"
                     /locus_tag="MIV85_003045"
     CDS             11514..12962
                     /gene="ddlR"
                     /locus_tag="MIV85_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBY2962369.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDIEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            13021..13827
                     /locus_tag="MIV85_003046"
     CDS             13021..13827
                     /locus_tag="MIV85_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBY2962370.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            13853..15772
                     /locus_tag="MIV85_003047"
     CDS             13853..15772
                     /locus_tag="MIV85_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBY2962371.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(16014..16361)
                     /locus_tag="MIV85_003048"
     CDS             complement(16014..16361)
                     /locus_tag="MIV85_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBY2962372.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(16348..18276)
                     /locus_tag="MIV85_003049"
     CDS             complement(16348..18276)
                     /locus_tag="MIV85_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBY2962373.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
BASE COUNT         6809 a         2698 c         2466 g         6460 t
ORIGIN      
        1 ggatacaaaa atatctataa acgaaaacat gagtctaggt aaaagatttt ttaaatacct
       61 agcaccatct gtagttgcaa tgtgggtttt ctcactatat acaatggttg atggaatatt
      121 tgtaagtaaa ggagttggag aattagcttt agctgctgtc aatatatcaa tgccttttat
      181 taattttata tttgcagttt ctctattatt ttcaactggt gcatctacca taattgcaat
      241 ctatctgggg aaaaaagata ttaaatctgc taacgaagtc ttttcattta acttagtatc
      301 aataattata ttatcaataa ttatattagc tataactttt tttaatttag atagattagc
      361 actattttta ggagctacag aatctacaat tggtatggtt aaagattatt taggaataat
      421 aatatttttt aacggattct ttatagtgtc ttattcttta gaagttataa taaaaactga
      481 tggctttcca atattagcta ctgttggtgt aataatatct gctcttacaa acatcatact
      541 tgattacttg tttgtaattg aatttggatg gggtgtaaaa ggtgctggta ttgcaactgg
      601 tttgtctcaa gtcttttcta ctattttctt cttaatacat tttttaagaa aaaactctac
      661 tttgaatttt tcaaaattta gaattgattt taagacactt agaaaaattg tatttatagg
      721 ttttcctgat tcaactactg aattaagttg tggtatagtt gttttacttt ttaacttaag
      781 tcttactaaa tatattggag aaaatgctct tatttattat agtgtcataa attatataaa
      841 tacattagta cttatgacta tgatgggtat aactcaaggt atgcaaccac ttactagctt
      901 ttattatggt gcaggaaata tagataatgt aaaaaaatta ttaaaaatgg ggataaaagc
      961 cacaataata gcatcagttg ctgtatttgc aatttgtatg gctttttcag gaccaatagt
     1021 ctctttattt atacatccag aagaaacaat gctattcaat gaaggagttc gtgtatttaa
     1081 aatattctct atatctttct tattggtagg aattaatgta ataatttctg gattctttgt
     1141 atcagtagaa aaaccatcaa tttctactgt tatatctctt ggtagagggc ttgtaatagt
     1201 tgttttaagt ctaatttcaa tgatactaat atttggtgga caaggaatat ggatgactac
     1261 tattgtttct gagtttatat gtcttatttt atcattagtt tttctaaaaa agaatttttc
     1321 tacattagac tctaatctaa ataaggttgc ttagatgata agagtgacaa tatatgaaaa
     1381 tatctaaata aaaaatacct attatacaat cttgcaaata ttaaaccttt gcaaaaatta
     1441 ggattatata ataggtattt tatttatgta attattttat ttctaaatat ccatagccat
     1501 cttttattaa agttcctttt acttcatatt ctacaggttt tttaaatatt ggaccatcta
     1561 cgacaaatgt atgatactct ccatgttctc cacatgggtc tgcaccagca ttttttatct
     1621 tctccacaag ttctctagtt aatttttttc ctaaaaattc ctctcctaag tgctttaagt
     1681 ttacttttgt tacaacacta caaaatccac tgtctataaa ttcatatact aaatcctctc
     1741 tactctcttg ccataatggt aaatctactt tcataccaac tgcttcacat ctatcagtat
     1801 cccattttct atgactttct atatctatat ctccatatgc acatatcgtt gctcccatgt
     1861 ttttagcttt tattaaagcc ctctcaaagc tctcttcata tccttctacg ccacactcag
     1921 caactaataa aggtaatcct atgttgctac ttacttgctt aagcatatta tattctaaat
     1981 tatgtgtcca tgactttcca tgttcttcac ttatagttgt caagagtgcc acaggcttat
     2041 atcctttttt caacattcga tttaatgcta atatactatc cttaccacca ctaaatgaca
     2101 ttacaaattt ttcatcagcc aattttaaca cctctttcat ctaactttgt tttattaaca
     2161 taattatacc aaatttttga gttgcatagc aaattatatt aaattgttaa ttcactataa
     2221 agaatgtccc taatattaaa agtataaccc ctatgtattt gtataaatgc attgtttctt
     2281 gtcccaaaat tacgctatca ataaaaaatc caactaaaac ttgggataca agagttaata
     2341 taagtgtatt tgatactcct aaatttggaa ttgcctttac tgtaaaatat attattagac
     2401 ctccaaatac tcctcctaat aacaacttat aattaaaacc atttatagat actagacact
     2461 ttaagtcacc tgtaactatt atacttgcca aaaaaaatat tgctcctaca gttaagctta
     2521 taaaggtggc cactaatgct gttgtacttt ttcctagctc tccatttata aaagcttcaa
     2581 gagctgtaga accacctgct aataatgcaa atattattgc ccataatttt gtcatggaca
     2641 aacctccttc tatataattc tattaataga agtttatgat acaacctatt aattaattac
     2701 taagtatagt ttaattttta tacactaggc tttatttgga tatgaatttc tgttataatt
     2761 gttctatcga ttttggaggt gattttatgt acacaaattt taatatcgat tttaataact
     2821 ttaataaaaa agaaaatgct attaaattta tgttaatggg agtattactc attatattag
     2881 gattattatg ccttacattt aagacattag gtataaaatt aatttcttgg acttttggta
     2941 ttgcactttt attctttgca tatttaaatt taaaaaatat taatgagtta aaaagatatg
     3001 ctactaaaga agaaattaaa ccctctatta atatccaatg ggttctaata attgcatgta
     3061 tattactttt tgtatttcct caaaaaatac aaagcatatt ttcattattt ttaggatttt
     3121 atttaatctt taatcaacta gtagcacttg taaatagtaa gaataatcct tattctaaat
     3181 ttacaacttg gaatatagtt aagattctat ttggtatatg ccttatatta tctccacttt
     3241 ttttatctag atttatagta tcgataatgt cttttttcat aatattattt ggactagttc
     3301 tatttttctc tggaaataca gcgagaaaat attaattatt ttctcgctgt atttttatat
     3361 tacttaaaat agaatttgtt taagttatct atttgtggta atatgttttt tgtacaagct
     3421 cagcgtacaa ttttattaga aataggtgat tttttggata aatttaaata tgcttttgat
     3481 aataaaagat atcatacttg gaattactat cttagaaata cttttggaga aaaagttttt
     3541 aaggtatcta taaatgcagg atttacttgc ccaaacattg atggaagtct tggttatggc
     3601 ggatgtacct attgtagcaa agaaggctca ggtgattttg ctggaaaccc taaagataat
     3661 cttatcagtc aattttataa tataaaagaa atgatgttaa aaaaatggcc tcatgcaaag
     3721 tatattggct actttcaagc ctatacaaat acgtatgctc ctcttgaagt tttaaaagaa
     3781 aaatatgaga ctatattaga acttgaagat gtcataggtc tttcaatatc cacaagacct
     3841 gactgtttgc cagatgatgt tgtagaatac ttatctgaac taaataaaag aaccaattta
     3901 tgggttgaac ttggacttca aacaattcat gattctacat ctaaaattat aaatagaggt
     3961 catgattata aaacatttgt tgaaggtgtt gaaaaactaa agtctaaaaa tataaaggtt
     4021 gtcgtacaca ttataaatgg tcttcctggt gaagattata atatgatgat ggaaacagca
     4081 aaggcagttg gtaaaatggg tgtagacggt ataaaaatcc atctattgca tgttataaaa
     4141 gatactccta tggaaaagat gttacaaaat ggtatgttaa ctcttatgga acaagatgaa
     4201 tatatcaatc ttgtctgtga ccaattagaa atacttcctg aaactatgat aatccataga
     4261 ctcactggtg atggtaagag ggatgaacta gtaggtccta tatggagcct aaaaaaatgg
     4321 gaaattttaa atcaaattga tgatacttta aaggctagaa attcttatca gggctgtaag
     4381 tttgtttaat acaaaataat aactatagaa atggttatat aaatatagtc ctttctatag
     4441 ttatttagta tttacaaaac aaaatattaa tttgtacatt tatacaatat ataataaaaa
     4501 atagatagtc taaactgtat ctacttatat tttatttgta ctgtccactt tattctataa
     4561 aatttataaa tagttatttt ttaataccaa atataatttg gtataatttt tgttggactc
     4621 taaaatgtat accaataaat cctttttaag tatataattc taaatacttt cagttttttc
     4681 aatctgcttt aacttgttgg acttataaaa tattcttatt tcatcataag aaagattaag
     4741 tgctactact gcagatatta acatcaacat cactccaaat aacttcccta aggaaaaact
     4801 ttctcctaat atagtgcaac caattattac tgaaccaact aattctactg atgccacaac
     4861 acctgcaact gacaactcta cacctttaga tatacctgct gcataaaaaa tatatgcaag
     4921 tgcagctgga acaatgccta acattagcat acaagataaa acatctaaat ccttagcata
     4981 atttaagatt tcccaaggtc ttgaagaagg aatcataaat atagctccaa ataagaaact
     5041 gtatactaat attgttgaac ttgaaaattc ctttaaagca tttttactaa tagttggcat
     5101 aagtgcatat gctattgctg ataatacccc aagtaaaagt ccaaaagcgt ttaaaccttg
     5161 aaaatccaaa cgtccaccag tcactgccat aattgcacca ataaaacaaa gaataagtga
     5221 aaataatttg cttctagtaa tattttcttt ataacatatt tttgaaaata ttgctaaaaa
     5281 cagtggtgat gtatatagta aaactgctgc aattgataca cccgcaatgt caattgcttt
     5341 aaaataacat aaattaaaca ttgcctgaca tataatacct attattactg aatatataat
     5401 tccttttttg cttatcttta agatttgtgg tgtccttata gatgaatata cgcctaaaac
     5461 tataaatcca aaaaacaatc ttgtaaatgc tacttgttct gatgtcagtc catttcccat
     5521 taaaaacttt ccaaataatc caagtgtagc ccataataac cctgctattg ctataaatac
     5581 atacccttta cttttttctc ccattttaaa ttcccttcta tttttattta gtcaatttac
     5641 actcttcttt ttaagcaaaa actatgccat cttaaatcaa tatatatcga ctctaaaacc
     5701 ctagtctttc caataatact aataaatttt caattttttt atatttattt ttcacttact
     5761 ttaagttgat ttagacttat tttaattgta aaatgagtta tatataactt atttaaagtt
     5821 aaaatagact gaaacttata tataaatatc aaattttaag tatattaatc aattaaacct
     5881 attttaatat atcattaaaa atttaggagg aaaatataaa aatgaattta gatttggaat
     5941 tttatcaaaa aatattagaa gcttcccatg atgaaatatg tgtttctgat gataaaggaa
     6001 taataatata ttgtaataaa gcatttgaag aaaattatgg tctaaaaaaa gaagatattt
     6061 taggaaaaaa tgtttctttt ttagaagact ctggatattc aacaaaaagc cccataccaa
     6121 ttgtattaaa aacaaagact aaattttcac tggaacaaga tactcaaaca gggaaaaagc
     6181 ttatcataac tgctacccct atatttgatg aaaatggaaa cttagaattt actgttgaaa
     6241 attgtagaga tataactgaa cttaataata taaaaaataa acttgaagac acaaaaaagc
     6301 aagtaaaaaa atataaatct gaagtagaaa cactatacag aactgcactt agaattgagg
     6361 atactgtaat tatggacgga atagttatga gaccaatcat aaacacagta aatcatgttt
     6421 ctaaaacgga tgtaagtgta cttttattgg gtgaatctgg aacaggaaaa agctcacttg
     6481 ctagatatat acaccacaac agcaatagat ctaatggccc atttataaca ataaattgtg
     6541 caactatatc tccacaactt cttgaatctg aactttttgg atatacttca ggtgctttta
     6601 caggtgcaag tactaaaggt aaagttgggc tcgtagaatt agctaatgga ggaactcttt
     6661 ttttagatga aataggagat ataccacaaa atctacaggc aaaatttttg caattaatac
     6721 aggatagaac ttttactcca gttgggagct taaaaaataa aaaggtcgat ataagaatta
     6781 tatctgctac aaatgttgat ttagtttcaa aagtaaaaga aaaaaagttt agagaagatt
     6841 tatactatag attaaatgtt atagaaataa aattgcctcc tcttagagaa agaagggata
     6901 atctagtgga aattataaaa tattatttta ataggtactc aagtgacttc aatctaaata
     6961 aaactatttc taaagaagct atggatgcta ttgcaaatta tagattccca ggcaatataa
     7021 gagaattaca aaatataatt caaaaaatct tgcttacttg tacagataat catataacaa
     7081 tagatgactt accaaacatt cttacaaaaa atatacatat taccaataat ggaaataaaa
     7141 cacatatatc ccaaattaat aaggttatta tatctgactc aaaatctact aattataaaa
     7201 ataaaaattt tgacacttta attaaagagt atgaaaaaaa tataattttg gatgcttatg
     7261 aaaaatttgg tagttcttat aaagtagcca aacaccttga aatctcacag tctaaagcca
     7321 ataggttaat tagaaagtat actaatactt aattttaaat ttgataaata aaaacttaac
     7381 actatttaca tattgtaaat ttggccattt actgttatta tgaatatggt tgaaattatt
     7441 taaataaata ctgttgactt agtttcatat atttaccatt aaacttttat cataaatatc
     7501 atatcataat aatatattta ataagtctaa taaactatac gaggtgtaaa tatgttaatg
     7561 aatacccatt ttattatggc aaaatcaata cttgataata tagatgaaaa taaaacattc
     7621 tttataagcg aaaaaaattt tatatatggc aatataaagc ctgatgcttt ttctaaatat
     7681 aaattaaaaa aacattattt agatgagtca tttaatatga ttgtttctaa aataaactat
     7741 ctatgcagtc ttaatataga tagtctttct aaatactttt cagtaagtag acttagtcag
     7801 gaactaggag tcatatgtca ttttttatgt gattttttct gtgtagctca cagtgaacgt
     7861 tgggagttta agcatagctt aaataaacat gttacttatg aaagagaact tggagcattt
     7921 gcaaaagatg ttgatttatc taaaattaaa tgtggtacta taaatagtag ttttgagaag
     7981 ttttttacta aactttatag cgattacaaa aagaaaactg attatatgaa tgatttaaaa
     8041 ttttcagctt atacttgtaa tagtgtcata aattatatac ttgactctat tttatctaat
     8101 acaataaaat catatcatat agcaaattgc ggttaactta agaattttta aacttatata
     8161 aacttataat tgaatataat taaaatgact gctctataga atataatttt atacttctct
     8221 aggacagtca ttttttatac taactattta tctccattat aacatctatg gcacttttta
     8281 cactatctac tacataattt gcactttgct ttacatcttc ccttgcctta gacattgcaa
     8341 aactatattt aaatccttct aacatgcaaa tatcatttgg agaatcccca atagtagcaa
     8401 cttcatctgg acttacattt aacgttttta ttacatgctc tatacttcct ctttttgaca
     8461 cacttttagg aactatattt aaagtatatg ttccagaaaa atatatttct aagacttcac
     8521 taaactcact ttttagataa agttctattc tggataactc ttccaaattt tcagaacata
     8581 cgcctatatt tcctataaga ttatcaaaac tacttctttt ttcaaagtct gggtcaacta
     8641 taaagtcact agaataatgt ctaaaagcag tggtatcact acccacaatt acatcaccct
     8701 tatatttaaa ataaagttgt gcatcacttg actcaaatct atcaatgact ttttttacta
     8761 aattatcatc tatcgttctt ttaaaaatta cattataatc tttatcatat ataaatgaac
     8821 cattttcaca tacatagtat ccattcatat ctaaactatc tttgataata ttatgtgctt
     8881 gtttaaaaat tctacctgta gcaacattaa actgtactcc ctttttttct atttcttcaa
     8941 ttgctactat atcttctttt gttatggttc cattttcata tagagttcca tctaaatcac
     9001 aaaatatatg ttttatcata aattaaaagc ctccaaaaac aattttatat tttactaata
     9061 ctttaatcaa aataacttaa agcttttcta attgtattct caactcatta agcaaatctc
     9121 tagtagctct taatcttatc tttcttctat ccccattaaa tatatttttc tttactattg
     9181 tttttccatt tatatatatt gcagtataaa ccagtcccac aggcttctct ttggttcctc
     9241 caccaggtcc agctactcca gttgtagata tacctatatt agctttaagt cctttagcaa
     9301 cgccctcagc catttctata gctgtttgct cacttactgc tccaaactct tccaaagttt
     9361 ctctttttac tcctaatctt ttcattttag aatcattaga atatgttaca caaccttcaa
     9421 gaaatacaga ggatatacct ggatagttta taagagatga agaaaccaaa cctccagtac
     9481 aagattcagc cactgctatt gttagatttt tttctacaag tagcttagaa acagcatctt
     9541 ctaaagcagt ctccccttca gatatggaaa tatctccttc agtatataca tatttaccaa
     9601 ctctactttt tattttttct tctactggtt ttattaattt aaaagcttct ctttcatttt
     9661 cagcctttgc agttattctt attgtaactt ctaattcttt tgcatataaa gcaactgttg
     9721 gattagtctg ctcattaatt atatcgagaa tttctaattc tagatttgac tcacctattc
     9781 catataatct taaagtctta gatactagca tttcatttgt gaattgttgt aagtaaggtt
     9841 tgacactctc attaaacata gctttcattt ctcttggagg tccaggcaat actattataa
     9901 atttaccatc tttttttaaa attgcccctg gagctgtacc attattattt tttagtacta
     9961 tagcatcttt tggaaagtac acttgtttca tattattttc ggccattttt ttccctgttt
    10021 taacaaagaa agattccaaa acctctagtg aaggtttatg tagttctaat ttctgaccaa
    10081 agtattctgc agcagtttct tttgtcatat catcaccagt tggcccaaga ccacctgtag
    10141 taattacaaa atcacttctc tttaagcttt catcaaaaca ttctaaaagt ctttgtttgt
    10201 tatctccaac agtactctga tggtatactt ctattcccaa tgatgcaagt tctttagcta
    10261 aaaattgaga atttgtattt actatatctc ccaataatat ttctgttcct acacttatta
    10321 tttcagcttt caaaatttat cactccttga tttatagcca ttaagactag tcttaagttc
    10381 ataacaataa ttttagcaaa aataataaca taaataaagt taaaaaatca tttaaacata
    10441 tctttaaact agattattat tctaaaacca cacataatat aaacttcgta tatagtggta
    10501 ctttcatcct caactgttaa ttcatataat taagtatgta aataaaaagt ttactttaaa
    10561 ataataaaaa ttaaaatagg agtgtataat atgaaaatag cagttataat gggtggaata
    10621 tcatcagaga gagaagtttc tttaaattca ggaaaagaga tatataataa ccttgataaa
    10681 aataaatatg aagttgtaaa agtaataata gatgataaaa aagatatatt tacaaagata
    10741 ccagaagata tagattttgc aatacttgct ttacatggaa aatttggtga agatggatgt
    10801 atacaatcaa tacttgagac tatggatata ccatactctg gatgtggacc tctttgcagt
    10861 gggatgtgta tggataaaaa tataactaaa aaaatgctta gagattcaaa cctacctact
    10921 gctccatggg ttttagtaaa atcagttgat gaaatagact atgatgaaat agataatata
    10981 ggttatccag tatttataaa accaaactca ggaggttcaa gtgtagccac attctttatt
    11041 cattctaagg atgaagttga agaagcagtt agaaaaggtc tggaagttga tgaatttgta
    11101 atgattgaaa aatatatacc aggtggagaa tatacttcat tcatattaaa tggagaagtg
    11161 ttccctacaa tatctataaa atctgattca ggattctttg attatgaagc taagtactca
    11221 gttgaaaaag gtgcaaagga agaagttgtt tacttagatg aagaacttca aaaaagagta
    11281 aacgaaattt ctgagacttg ttggaaaatt tttaattgca aagcatatgt aagagttgat
    11341 atgattataa gtgaaggtat tccatatgtt cttgaactaa atactcttcc tggaatgact
    11401 caaactagtt taattcctag aagtgctgct gctagaggta ttaagtacag tgaactatta
    11461 gataaactta tagaatactc tttaaattag atgaaataat ttgaggtggt aatttgatat
    11521 tttcaaatct aaaactaaat gataatgaac caatttatat acaacttaaa aattatataa
    11581 gtgatatgat atcaaaagga ctaattccag acaatagtaa gctcccttct acaagggagc
    11641 ttagtcagct tttacaagtt agccgaaatt ctgtagtttt aacttatgaa gaattaaaat
    11701 cagaaggatt aatctactct atttcaggaa aaggtacatt tgttaaatca aagaataagt
    11761 cttcaaatac tacatggtca ttaaactggg attgtttaga gaatacatac tctaaaaaag
    11821 ccaatgaatt ggacattata aaaagtgaaa ttccttggag ctctgacctg atttccttta
    11881 aaagtatttc tccagatgga gatttattcg acatagaaga attaaaaaaa tcctttttaa
    11941 atagaatttc actagaagga cataaattac tcaactatgg atatgcacaa ggttataagc
    12001 cccttattga ctatttacta gaatatatga caaataaggg tgctgatata agtaataaag
    12061 atatactaat aacaaatgga ttcacagaag gctttgatat tattatgtca tcttttaccc
    12121 aagaaaaaga ctacataata tgtgaaaatc ctactcataa tactgctata aaaattatga
    12181 aatctcataa cctcaatatc ttaggtgtag atataaatga agatggtttg gacttcaata
    12241 tgctagaaga caatttagtt aagtataaaa ataaaataaa gtttgcatac attacaccct
    12301 cttatcacaa tcctacagga attgtaatga ctcctgaaaa taggtacaaa ttctataatc
    12361 ttatgaaaaa atacaatata gcaattatag aagatggatt taatgaagaa ttactctaca
    12421 atagttctca tatatttcct atctgttccc tagataatat gaataatggg gtcgtatata
    12481 ttggtagttt ttcaaaaatt ttatttcctg gaatgagaat tggatggata tttgcagata
    12541 aaaaagtaat caataagcta gaaagtgtaa aaaggtgcag aaacatacat gtatcctttt
    12601 tggaccaagg aattttattt gattatttaa gtaatggagg ttttgaaaaa tacattaaaa
    12661 aaatacgtaa attctatggg gacaaattta actttgcata taagtgtata aaaaaatata
    12721 taaaaacaga atatatcttg ggtgatggtg gtttgcatat atttataaaa ctaaaaaata
    12781 tagatactag agttttatta gaaaaatgtt atgaaaaaaa tgttatattt atgcctggag
    12841 atttattttt tacagataac tctggttttg atactttaag actcggattt tctaggttgt
    12901 cttttgaaga cattgaaatt ggaataaaaa taattggaga aactataaat gaaatgttct
    12961 aggttaacta aatattgtta gcctagttta tttttatgag gtataatata tatagtttat
    13021 atgaatctaa tactggggga taatatgagt aaaaagtcaa aacgaagaaa aattaataaa
    13081 ttaaaattaa cgattgtaat aactgtatta tttcttgctt tattatctat atatgagata
    13141 ctgttctcta atcccaacaa aaaaggtaat ataaagagtc aagaaactat gcaaaataaa
    13201 aataatacaa cagatgattc taaaaataat caaagctcta ccaaaaagca ggaagataat
    13261 aatatcaagc ctactttttc atattcttca ataccagata atataaaaaa taaaatgatt
    13321 ggtaaatcta tgcctactga tgaacctata agctttgata gtctatctta tttaaaactt
    13381 acatattatg gatttgatga aaaaactcat caaggagaaa tgatagtaaa cagtgaacta
    13441 gctccagaag tagtggatat ttttaaggaa ttatacgaaa aaaaatatcc aattgaaaaa
    13501 attaagttaa tagatgacta tgatgctgta gatgaaaaat ctatgtctga taataatacc
    13561 tcatcatttt gttatagaac tatagctggt acaaatgtag tttcaaatca tggtaaagga
    13621 cgtgctatag atataaaccc attacagaat cctcaagttt ctggaaatga tgttacacct
    13681 aaagtaagta cagtttatgc tgataggtct agcacaaaat ttggaatgat aaaaaaaggt
    13741 gatgattgtt ataatgcttt tgtaagcaga ggttggagtt ggggtggcta ttggaaaaac
    13801 ccagattatc aacattttga aaaataatag attagaaata aaggtgaatt atatgaattt
    13861 aatgacattg gaaaatataa gtaaaagcta ttctgaaaaa aaattactag aaaatatatc
    13921 tcttggaata aatgaagggg aaaaaatagg acttattggt gtaaatggta ctggtaaatc
    13981 taccttactc aaaattattg caggagttga agaaagtgag actggtaata taacaaaaac
    14041 taatggtatt aggatagaat atctacctca aaatccaact tacaatgaaa attcaactgt
    14101 acttgaacaa gtatttaatg gaacttctga agaattaaag ctacttggtg aatatcaaga
    14161 aatcctagaa aaacttaatt caaactttac agaggaatta aataaaaaat tattatcagt
    14221 acacgaaaaa atagatgcct taaatctttg ggatttagaa agtgaagcta agtcagtact
    14281 tacaaagctt ggtataaatg actttaatca aaaaatagca gaactttctg gtgggcaaag
    14341 aaagagagtc tctctggcat cagcccttat tacaccttgt gagtttttga tactagatga
    14401 gcctacaaac catctagaca atgatactat agattggctt gaggaatatc ttaattccag
    14461 aaaaggctca ttgcttatga taactcatga tagatacttt ttagaccgtg ttacaaatag
    14521 aattattgaa ctggacaaag gtagattatt cagttatgat gggaattatt caatattttt
    14581 ggaaaagaaa atggaaagac tttcgctaga agcaagtatt gaagataaaa gacaaaattt
    14641 aataagaaca gagcttgcgt gggtaagacg aggagctcag gctcgtagca ctaaacaaaa
    14701 agctcgttta caaagatttg atgaacttat aaatagagat tcttttaaac ctgatgaaaa
    14761 tcttgatata tctgttgcat caagtagact tggaaataaa ataatagaaa tacacaatat
    14821 atctaaatca tttgaagaaa atactgttat agataattta gaatacactt taactcgtac
    14881 agatagaatt ggtataatag gcaaaaatgg tatgggtaaa tctaccctta taaatatact
    14941 taatggagaa atagagcctg atagtggata tatttcaatt ggagaaacgg ttaaaatagg
    15001 ttgtttttct caagacgact ctcatatgaa tattgatatg agggctatag actatgtaaa
    15061 agaagctagt gactatatag aaacttcaga tggtactagg attacagctt ctcaaatgtg
    15121 tgaaagattc cttttcaatg gtactatgca atatactttg ataggtaaat tatctggtgg
    15181 tgaaagaaga agactacatc ttcttaaaat ccttatgaca gctcctaatg tgcttctttt
    15241 agatgaacct acaaatgatt tagatattga aacgcttaaa atattagaag aatacctaga
    15301 cgaatttaaa ggtgtagtag ttacagtatc acatgataga tatttcttag atagaatttg
    15361 taataaaata tttgcatatg aaggtaatgg aaaaattcat atctatacag gtaattacag
    15421 tgattatctt atttatagag agattcaagg aattgaattt gaagaatcta aaaaggaatc
    15481 agttaaaaaa gatgactcta ctaccctaaa aaaagaaaaa cctaaaaatg ataaaaagct
    15541 taagttctca tataatgaac aaagggagtt tgaaaatatt gactctgata tagaaaaact
    15601 cgaatctaaa attgcaacac ttgatgaaag tactgcaaaa ttttcaactg attttactaa
    15661 acttcaagaa attttagatg agaaatctaa actagaaaaa gaacttgaat acaaatatga
    15721 aagatgggaa tatttaaata atctagctga tgaaatagct aataataagt aatattaaaa
    15781 taatcttaag tttaataagt tttgctttaa atctgtaatt tataaatatt ttaaaggaag
    15841 tgtctcaaaa tgaacttttt agttttatga gacactcttt tttatgagaa atcaaatata
    15901 ttttcatcat ttcaacaata caaaagaggc ttatctctat tttgagacag cctctttcat
    15961 aattaccttc taatttatat gctctaatat atctataata attcttatta tatctatata
    16021 tccagtcttt caatataatg acaattaact tcaatatgat ttaaaaatac taacaacctt
    16081 tcataaagtg gatgagattc ttctccatat ttagcttcta ggttcttgcc tatttctcta
    16141 acagtccttt gaccatcaat ttgtaaaaaa acaaaactgg aatattcatc tagttctatt
    16201 tttttgtatt taggtattct agcttttaac tttctaaaaa acttttgaat tttatggtcc
    16261 tgtttttcaa gtatagtaac aactctattt tcagctactt catattcaag tccatcagta
    16321 attttaaata caatatctaa aacatcatta ctcttgctca ttatttttta ctttagataa
    16381 aacaataggt aatgctgtaa gcacaactaa aactactaat aaagcaattg ccattgaatt
    16441 tgttgcagca aatccacttg gtacctttgg agttacaact ccagttactt gtaatattat
    16501 acctattaaa ccaatgatag aaccaccagc aacaagacca gaagataaac ttataccatt
    16561 agaaacttta acttcttttt ctttttcagt tttagatact aattcaacaa ataaacgaat
    16621 taatgctcca actaatatta tagaagttgt tgcaattggt aaatagaatc ctatagctat
    16681 agtcattatt ggtaaattta atgcatatag aactattgcc ataaatactc caacaataat
    16741 cataacccaa ggtaaactac ctgacataat accagaagtt aatgttgaca ttaagtttgc
    16801 ttgtggtaat gcaaattgta cattatcacc agttgctcta agttggtcag aaagtaataa
    16861 aattactcct acaacaacta taacaccaac tatacttgca attgtaaagt aacgttgcat
    16921 ttcgtttttg ctaccaccaa taatataagt tactttttga gattgagtat aacctccagc
    16981 tatagcaata gcaacaacta taaatgaacc aaataaaagt aatgatttat tagcttctaa
    17041 atcagtccat cccattataa caaacactaa tgttacaata actagagaag ctatagtcat
    17101 accagaaact ggaagatttg atgttccgat tgttcctgtt aaacgaccag ctactatgac
    17161 aaataataaa gataataaaa gagatatgat agctccaata attgccataa caatgttacc
    17221 agaaattaag aatgctgcta aaaatccaat aactactcca cctaataaaa gtatcatttg
    17281 tatagatgaa ccttcttctc cttctccagc acttgattta gctttaagtg tttcttttat
    17341 agaagcgatt atagttggta taagttttat tgcaccaata atacctccac aaagcatcat
    17401 accagcacct atatatttta cataactact agatattgct ccaacatcca tttggttaag
    17461 aggcattgca ggattattcc ataccatagc tccatcttta gccatatctg taaagtatcc
    17521 tattaaaggt gctataccaa agtttgataa aatacttcct gcaaacattg ttaaagaaac
    17581 ttcaagccct actataaatc caattcctaa aagtagagga tttacttcaa tatcaaattt
    17641 ccatttgtag aatttgcttc ctacaagact cattacattg tttgctacat ttaagaatga
    17701 accagttaat acagtaataa atccacttat tacaaatcca attcccatgt acttaattga
    17761 atctccacca gcctctgaag caacaagtgt ttcagatata gccattgatt ctgggtacat
    17821 aagtttacca tgttcttcaa ctattagata gttgtgaact atagcagcaa ttcctatacc
    17881 aaataaaact ccaccaactc caacagctaa gccttcaaag aatgtaattt ggcttccaat
    17941 taatataact gctggtaata cgaaaataaa tccacttgca acagattctc caccacttga
    18001 cataccttgg attaagtttt taccaagaat accctttgaa cgagcaaatg ctccaacaaa
    18061 agcagaacct attatagctc ctggaatacc tgcggcaact gtaagaccgg ctttcattcc
    18121 agagtaagtt gtagatgcgg caaaaatggc agctaaaata ataccgataa tcagtacagc
    18181 tacatttcca ccggttctgg acttatctgt gatatatgga acgtaatctt ttccactaac
    18241 ctcaccataa gcacccttag gtaatttttt gttcataaaa ttttcacccc ttttcaattt
    18301 gtatatatta taacatatat acatataaaa cttaactttt tattatttta caaatagcga
    18361 gtcaaaacta ctaaaattta accctatatt attaatttct acttttagat atttttatgc
    18421 taattttctt ttt
//
LOCUS       DAGQVA010000080        18405 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.080, whole genome shotgun sequence.
ACCESSION   DAGQVA010000080 DAGQVA010000000
VERSION     DAGQVA010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.080"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(229..909)
                     /locus_tag="MIV85_003050"
     CDS             complement(229..909)
                     /locus_tag="MIV85_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962374.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(959..2974)
                     /locus_tag="MIV85_003051"
     CDS             complement(959..2974)
                     /locus_tag="MIV85_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBY2962375.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(3046..3723)
                     /locus_tag="MIV85_003052"
     CDS             complement(3046..3723)
                     /locus_tag="MIV85_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962376.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(4303..4386)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(4619..5461)
                     /locus_tag="MIV85_003053"
     CDS             complement(4619..5461)
                     /locus_tag="MIV85_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2962377.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(5713..7497)
                     /gene="pepF"
                     /locus_tag="MIV85_003054"
     CDS             complement(5713..7497)
                     /gene="pepF"
                     /locus_tag="MIV85_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBY2962378.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLVHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(7563..8228)
                     /locus_tag="MIV85_003055"
     CDS             complement(7563..8228)
                     /locus_tag="MIV85_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBY2962379.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(8379..8540)
                     /locus_tag="MIV85_003056"
     CDS             complement(8379..8540)
                     /locus_tag="MIV85_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBY2962380.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(8618..9127)
                     /locus_tag="MIV85_003057"
     CDS             complement(8618..9127)
                     /locus_tag="MIV85_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBY2962381.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            9333..9551
                     /locus_tag="MIV85_003058"
     CDS             9333..9551
                     /locus_tag="MIV85_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBY2962382.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            9569..11515
                     /gene="feoB"
                     /locus_tag="MIV85_003059"
     CDS             9569..11515
                     /gene="feoB"
                     /locus_tag="MIV85_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBY2962383.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(11694..12749)
                     /locus_tag="MIV85_003060"
     CDS             complement(11694..12749)
                     /locus_tag="MIV85_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBY2962384.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(12797..13597)
                     /locus_tag="MIV85_003061"
     CDS             complement(12797..13597)
                     /locus_tag="MIV85_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBY2962385.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(13590..14381)
                     /locus_tag="MIV85_003062"
     CDS             complement(13590..14381)
                     /locus_tag="MIV85_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2962386.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(14421..14843)
                     /locus_tag="MIV85_003063"
     CDS             complement(14421..14843)
                     /locus_tag="MIV85_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBY2962387.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(14859..15338)
                     /locus_tag="MIV85_003064"
     CDS             complement(14859..15338)
                     /locus_tag="MIV85_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2962388.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(15470..18226)
                     /locus_tag="MIV85_003065"
     CDS             complement(15470..18226)
                     /locus_tag="MIV85_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2962389.1"
                     /translation="MRDEILSFVNECVLFNSFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGIAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT         6022 a         3155 c         2024 g         7204 t
ORIGIN      
        1 tatatagatt tagatataca atttatccat cttttcaaat ataatctata aaataatagt
       61 tccattacgc atttttttat ataataaaac tgactgtaat ttaactggca aagtctagaa
      121 gaataggatt tatcaattaa attacagtca gctattttat aataatttag tttagatatc
      181 gttagtattt cacatttata acaattatta atgatattaa tatatttatt attccttatt
      241 aaaataatat cctgctcctc ttattgttat aattttctga ggatttttat aatctttctc
      301 tattttcttt cttaatccat tcactgcaac taccacacta tagttatcct ctaagtattc
      361 attcatccat acatgttcat atatctcttt agtagtcaaa gtcttttcag gattctctat
      421 aaaaaagttt aacaacttat tttctgttgg agtcaatttt attattttat cttctaactt
      481 tattactcca ctagttctat tatattcctc taattttgta ttattttcat tattatttac
      541 atatgagttc attcttctta aaatagcttt tacttttgcg tataatattt ctaaatttag
      601 aggctttatt aagtaatcgt ctccaccaga atttaaagca tttaaaatgc tttggtcttc
      661 atttatataa gtcatataaa caattggaca agtagttaca tttctaattt ttttacaaag
      721 agtccatcca tcaccatcac ttagaattat ttctaaaaat attaaatcat atttattgct
      781 aaatattttt ccaatagctt cttcacaatt atatgctaaa tctatactta ttcctttttc
      841 ctccagaaat ccttttagct tctggcaatt atccttgtct ccatctatta tcaatatctt
      901 agtttgcatt ataatcactc ccaaatatca ttattctttt atattaaata agctattatt
      961 ataaaaaaca tagacttaat tttattgtaa aaacagttcc ttttcctagt tctgaatcta
     1021 caaatatttc tccaccatgc tctcttataa tggatttgac aatatatagc cctaaccctt
     1081 gcccttttgg ctcattattg tctctttctg taaagaatct gtcaaatacc tttggtatat
     1141 tttctggagg tatacctttt ccattatcag aaattttaat aattgcaaat ccatcttctt
     1201 tatccattga taaaattatc tttccatcaa atggagtaaa ggtcaaagca ttataaatta
     1261 aattctcaaa tgctcttgta agcatctctt tatttatctt tgcatatatt tttttctcca
     1321 atacataagt ttcaaagttt acaccacatg cttgtgtatc tggcaaatta ttttcatata
     1381 tctctttaat aaaattattc agacatattt tttcactaat accaatgctt ttatcttgtg
     1441 atgtaaattc ttgcaaacta cgtactctat tttgtacttc atttgacttt tgatttatag
     1501 cataaagata ggttcttgtc tcttcatcta catgaatatt accaaccttt atcaaatcta
     1561 taaatgcttg tatagccgaa acaggtgcct ttaaatcatg tgctacatct gccaagaatc
     1621 ttttacgttc atttaacaat gttgtaagtt cattagttct cacttcaact tcatgttcaa
     1681 gattccttgt aagtttttca ttctctttta ttattattct attcctgttt atcatcataa
     1741 cagaaaataa aataacaatt acaaacccac aatattctgt ttgccaccct gtaaatatag
     1801 gctcaaatct attactcgta actgcatcaa ataatatgct aattccaaaa acagtgttta
     1861 ctgaaactaa aatataagaa cttatatgct cagagcatgt ctttttatat attgaaacca
     1921 gcgaagacat taatatatat ataaatacaa tatatttata tatgtctatt aacttcccat
     1981 atatgttgac aaagtacata tcatatggaa gaagaataat tggtatcact atagatatga
     2041 tactcattgt aattcctaat ggtaaaatta aaaatctata cactttattt tcttctattt
     2101 tggatatact tccatttata caaataatac ataaaactac cataaaatat gacaaatctt
     2161 caaccgcata tgtaaagctt accaaaggca gtcctaacaa atgtacaaag ggataggata
     2221 catggatggc aaagaaaaca cacatacatc caaaatataa gtaaatttta cttttgtttg
     2281 aaagaaacca tacagacaat gaaaatatag ctattgcaaa agttgtgaag caaattatac
     2341 tataaaaaag taatcgataa aacatcatat tacttatgtc ctttgtttct cctaatgcag
     2401 gcggataata caaaccacta taataatgtg aaaaattcga tacattgatt ataatttctg
     2461 tatttttctt tgcaataaaa cttactactg aatttttaat tttgggtcta tatttttctg
     2521 ttcctacatc tcctaattta gaaaccattt ctccatttat ccatacttca cttgcggaaa
     2581 aaatctcagg aagctctaaa cttagtagct tatccttgcc ttcatttttt attctcatac
     2641 gataagtagc attcccatat ggtgactgag tcccttttct catagaaaaa tctggatatt
     2701 gacctataaa aacatattct ggttttatat cttgctctgt aaaatcattc ggtttaaata
     2761 ttttatgatt ataaaactcc cagtcatcta tcaaaaagac aagtttacct ttagtgaaag
     2821 tatcattatc tatagttaaa attccattac ttgctctaat agacttatat gtatatttat
     2881 tatcatattt atacagaaga tttaatcctg ttattgccag cagagagact atcaatacaa
     2941 tgagagttcc ttttagtata ttatactttt tcattgtatc aaccacatct ctttcatagt
     3001 agtattaaat aaaacaagaa ctatttatta attacagtat ctcacttatg gtacaaactt
     3061 atatcctttt ccccatacgg tttgaatgta ttgatgctcc ctgcttaaag aattaatttt
     3121 ttttctcatc tgtgcaatat gaacctgcac tgtatgttga tctccaatat caggcatttt
     3181 ccaaacttgg ttatatatct ctatctttga aaatacttgt tctttgttct cagctagaaa
     3241 caataatatt tcaaattcca tagtagttaa atctatactt tctccatcaa aagttacttt
     3301 tcttgaattt acatttatta ctaacgctga aaactttaac acattaggaa ctgatgtaat
     3361 atttttgtac tgcctcatac gagcatatat tctaagttca agttctttta aactataagg
     3421 ttttgttata taatcatccc ccccagctaa aaatccccga actttttctt cttcatgctc
     3481 ataattagat aaaaatatta taggtatgtt aaccttttct tttatatcat tgcacatttt
     3541 atatccatct atatctggca atgaaatatc caaaattata cagtctaaaa ctatactctc
     3601 tactatatcc atagcatctt tagcagtctc tgatgtatat acattaaaac ctatattaga
     3661 aaaataaatt tgatttatgt ttaaaatatc aacatcatca tctacaacca gtaaattata
     3721 cattacacca ctccattcaa aggtatttta attataattc caagttttat agttattaca
     3781 aattataatg ttttattttc atatataact ggtattatta ttttataata tctttacaaa
     3841 ctagactata atacttaagt atttttgaat aattcttgaa tattgtatta aacattaaga
     3901 ttcattatta aatactaatt aaagtctccg attgttggag aatggagctt aaagtcattt
     3961 tcacgtataa atttattatt tttctagaaa cttgtctatt ggctagtttg agtattgatt
     4021 tatatgattt atatggttat aatataaaat aaattgtatt attttggtaa atatattgtt
     4081 acaaaaggtt tatattctgc atctcaatgt ttataaaaac tttattttct tattataata
     4141 ctattattct tttaaaaaaa tttccctttt ccaacaaatg gctactttaa aagccaaaat
     4201 tttacctatc aataaaaatc ttaacgacta atactcttat tttcaaattt tgcaacattt
     4261 ttgttaattt taaaacaaaa aaagactatg caatataaaa attatattca tagccggttg
     4321 caccactaac tccatatatc tctagatgcc caataataag atatacttct cagtttctaa
     4381 aatattttta ttaaaaatct tttatatatt ttcataaatt tcttttttat tctaacattg
     4441 taatattatt ttgtcaatat ttccatattc ttagagataa gatactaaaa tacctatttt
     4501 atctaaagat atttatattt ctacattcaa taatagacaa taccctgcaa gttaaagcat
     4561 catttttatg agcttatctc acagggtatt atatgtttac tttatattat aactcttgtt
     4621 attgattaac tttaataaat cctttttctg aaacaagtgc ttgtccttca tcacttaata
     4681 tataatctat taaagcttta cctttttctg acaaaccatc ttctttatta actaatataa
     4741 atggtcttga tattggatat ttattagcta ttacatttgc atcagttgct tcaacatcat
     4801 ttatttttaa actatttact ttctcatcaa catatccaaa tgatatatat cctatagcat
     4861 tttcatttcc ttcaactgta gtttttatat ttcctgaacc atcacttatt tgtgcatctt
     4921 tagttagttc ttctgaatca aaccctacaa tttcttggaa tccatctcta gttcctgaac
     4981 cttcttctct tgatactatt actattggtg catcatttcc tcctacttct ttccagttag
     5041 taatctttcc tgtatatata cctttaactt ggtccattgt cagatttttt actgagtttg
     5101 cagtattagt tatcaatgct ataccatcta ttgctatttt agtttccttt aatccagcac
     5161 ttttttcttc atcttttaaa tctcttgaac tcattcctat ttcagatgtt ccttctatag
     5221 cattttttat acctccagaa gaaccaatct gttgtacttc tacactaaca ccttgatttt
     5281 tttcttgaaa cttttctccg atagtttcca taagaggacc tattgaagtt gaacctgaaa
     5341 cagaaacttt gcttgaatct cctgaatcac ctgaacctcc tgagttagaa ctacatccta
     5401 ctgctaaagc tccaactaac attgtactag ctaaaagaac gcctattttc tttttaaaca
     5461 ttttacttac ccccgcttat attttaattt tttgttgtca tttttctata ttttaataat
     5521 acagattctt tgttaaatga atattagagc agggttaagt aaatgtaaat attgttaaat
     5581 acatgtaaaa acttaatttt atatgattta ttcttaatta gattaacttt ttaaagttac
     5641 tttaggcaga tataaacata atacaactca tattatcaga agtcttcatt gaagctatca
     5701 acctatcaca tcctataatt ctttttctag tttattaact aattcagcaa atacatttaa
     5761 ggcttcctct atagattctt ttttcgtcat atctacacca gcagatttta attgttctag
     5821 tgggtattct gaccctccac tttttaagaa gtttatatat ctatctactg cagtacttcc
     5881 ttctgaaagt atctgttgac ttaaagcact tgcagcagaa aaccctgtgg catacttata
     5941 tacatagaag tttgaataaa aatgaggtat tctcgcccat tctattccta tttgtttatc
     6001 tactattgca gattttccgt aatacttttc atttaatttg tagtatatat tagtaaattc
     6061 atcagcagta agtggttctc cactctctac cctttgatgt acaatttttt caaattcagc
     6121 aaacatagtt tgtctatgaa ctgtagttct aaattgttct aaataataat ttaataagta
     6181 tatagtttca tccttagact tagaattttc taataaataa tttataagaa gtaattcatt
     6241 taatgtagat gcaacttctg caacgaatat cttatagtcc gaatataaaa atggttgact
     6301 tgttcttgaa taatgactgt gaacagagtg ccctaattca tgaactaaag tgaatagaga
     6361 attaaggtca tttttatagc tcattaatat ataaggatgt gaatcataac ttccccaaga
     6421 ataagctcct ccttttttac cttcattatc atatacatca atccaccctt catcaaaagc
     6481 actttttatg accttcaagt attcttctcc taaaggttta agtgcctcta atatgatatc
     6541 ctgtgcttta tcatatggta tatccatgtc aaatttatct gtcaaaggaa catacaaatc
     6601 atacatgtgt atttcattca atcctaaaaa tttcttttta agctcaacat atttatttag
     6661 attaggaata cttttatcta tagctgatat aagattattg taaacatcta aacttacatc
     6721 atctgaaaat aaagacgctt ctattgctga attatacttt ctagtttttg cgtaaaatat
     6781 ctctgatttt attccaccat aaagcgttga ggcaaatgta tttttatatt tctcatatgt
     6841 tgaaaattca ccttcaaaag cgtcttttct aactctacta ttcttacttt ttataaataa
     6901 agagtagttt gaatgagaaa gcttaacctt attcccctcc tcatcttcta tctcaggaaa
     6961 ttccatatct gcatatgcta acatatcgta tacattttct ggaattgtcg ataattctga
     7021 tgtagctgca agtatttctt cctctcgttc actcaaagta tgtggtttat ctctcaatat
     7081 atcctttata tattttgtat aaaaggatag cttctcatct tttaagtatt cacttaactt
     7141 attctcttct atcgccagta tttctggaac tatataagaa gtagccacac ctaaatcagt
     7201 agataacatt tctgtcttag tggctcttcc ttgattatca ttaattctag tatcttcatg
     7261 ttgtttcata tgagtatata catataaatt ttgaacaatc ctagatgcat tttcagagat
     7321 atttaatact ttatataagt tctccttact ctcagaaagc ttccctttat attcttttac
     7381 ttcttggata agatttttta ctttacttat gtctttttca atttcctctt tactggagta
     7441 catcttatct atcttccatt tgtacttttc ttctattgta cttctatcag ttcccatatc
     7501 atacacctct attttaattt gttttatatt ttattcactt tacaaaatat attgtatata
     7561 ttttagtcca aataatctac atttattact ccttctatca tatttatttc tttcataaca
     7621 tcgtgtaagt gtattctctt agcataagat acaaaaaaat taaccttcca gtattcttca
     7681 ttacgacatt ctatttccat atttcttacg ataagttgat ttttttcaaa tttatcatat
     7741 aaaaaaggta tagagtccaa attgcttaat tttaatatca atacattctt ttcttggcta
     7801 aataaaaacg tattgattat cctaagcaca aataatgcta tcattacaaa taatccacct
     7861 agaattgcca attcataata accatatcca actgctatac caatacatgc agttgcccac
     7921 atcccagcag ctgtagtaag cccttttacc ccacctttat tttttaaaat tgctcctgca
     7981 cctaaaaaac caattccaga taatacttga gcaggcattc ttgctgggtc agcatttgta
     8041 tacaaattat aatcaaagaa taattgaatc gaagttattg aaacaataca agaacctatt
     8101 gcaattagta tatgtgtcct aaatcctgca aactgtctta ttttttctct ctctaagcct
     8161 attattcctc ctattattag tgctaatagt aaccttattg ctatctcctt acttcctata
     8221 tcaatcataa tataaaaccc tcctgactta attacaactt atgtcctaca gataatttac
     8281 acatcagaaa tactatttta tatcttaata ttattattaa tatatgtaaa atatagccat
     8341 ctgttaattt ttgatacaaa aaaacccaca actgtgggct atttgcttag gtacatgtat
     8401 ttatttatta atatatctat tttcttactt gattctacta actcttcttg aaatatttct
     8461 ggatattcta tgtatgtatt tatctcttcc ctaactgctt caatctcatt ttttaacgct
     8521 tctaattcat tgttcgccat aataatcacc actattacaa atttgtatat ttttatatac
     8581 attttatcaa acaatattat attttgtcaa tattatgtca ataaaactta ctataaaaat
     8641 gctttaattt aggtattgta tacctggata ctaagcctac aaacatacca gttactaatg
     8701 atgccattaa cataaatggt aagtacccta tagcaagtat attttctatg attaaacttg
     8761 caactattaa ttgacctata ttatgcccta ttgcacctat aatgcttatc cctattagtg
     8821 ataaatcttt tattttactc gctaaataca taaataaaag actcagataa gctcctccta
     8881 tactaaatag tagatatgat aaagggcctg caaatattga tgacaaaatt accctgatag
     8941 taacaattat aacagtatct ttgacaccta acaacattaa tgaaattaaa gttataatat
     9001 tgctcaaacc caattttgcc cctggaaata taactataag aggatttggt atatatgtct
     9061 ctaatacata taaagctaaa ctatacccta tcataagacc taaaaatgtc atttttctag
     9121 ttttcattaa gttaactcct ccaaatttta tctatcatct tacattataa tacaaaatat
     9181 ataaaaacac ctaatttaga ctaaaatatt tttaatctat ttagaataaa tattagttat
     9241 ttcaatgtgc aattacctct ataaatcttg actttttgta tcatacttgt tacaatttta
     9301 atgataatga atttcattag gaggtgttaa taatgactgt ttacgattta aaaataggag
     9361 aaaaaggatt tattaatagt atagatggag atattaaatt atctaaaaga ttgcttgcac
     9421 ttggatgtat aaatagtact gaaatagaag ttaaaaaggt tgccccactt ggagacccaa
     9481 ttataattag atttagaggc tttgaccttg cgattagaaa atctgatgct aaaaatattt
     9541 ctttacaata atagaggagg agctacccgt gattaatgta gcattattag gaaacccaaa
     9601 tgtcggtaaa actactgttt ttaatctact tacaggttca aatcaatatg taggtaactg
     9661 gcctggtgtt actatagaaa aaaaagaagg atttcttgga aaagagataa aggttgtcga
     9721 tttacctggt atatatgcaa tggatacttt ctcaaatgaa gaaaaggttt ctaaatcata
     9781 tttagaaaat gaagatgttg atgtaatagt aaatgtagtt gatgcttcta atttatcaag
     9841 aaacctttac ttaacaactc aacttatgca atttaacaag cctatagtta tattgcttaa
     9901 tatgttagac attgcagaat ctaaaggagt taatatagat gccaaaaaat taagtgaaga
     9961 acttggagta attgttgttc caattatagc aaaaaagaaa aatggtgttg ataggataga
    10021 agaagagatt aagggagcta cgcaaaaagc ttttatatat cagaaaaact ttggaagtga
    10081 aacagaaaca tataaaaaat tagaatccat tttatcgaga tgtacaaaaa ctacatatac
    10141 acaaaagaaa tctatcagtg ataagataga caatatagtc ttgaatccta tattagcata
    10201 tccgatattt attggtgtat tgttcctctt atttaaattt acctttgact gggtcggagg
    10261 accactacaa gagggatttg ctagtcttat agaggcttat atttctgcac ctgttagtga
    10321 tatgttatct aactctagcc catggtttaa atcacttata gttgatggaa taattggagg
    10381 tgttggtggt actttaccat tcttcccttt aatatttaca ttattctttg gtatatcgtt
    10441 gtttgaagat agtggataca tgtcaagaac agcattttta atggataaag ttatgagaaa
    10501 ggttggtcta tctggtaaag cttttatacc tatagttatg ggtatgggat gttcttctcc
    10561 agctataatg gcaactagaa cattggaaag cgaaaaagat agaagagtta cagctcttat
    10621 tgcaccactt atgacttgtg gagcaaagct acctatatat gcactatttg tagctatatt
    10681 ctttccacat aatgctgctt tagtaactac atcactgtat ttggtgggta tagttatggc
    10741 aattgtagtt gcattattct taaataaaac agcctttaaa acagaggctg aaccatttat
    10801 attagaatta ccagaatata gaatccctac tatagatgca cttattaaaa atacttggaa
    10861 taaatcaaaa ggtttcttga taagagttgt tactgtcatg tttgcaatgt cagtcgtaat
    10921 ttggggactt tcttcattca atgtttttgg atatacagaa gatataaatg taagcttctt
    10981 ggctactcta ggtcatatta tatctcctat attcaaacct cttggttttg atgattggag
    11041 aacttcagtt gctattttaa gtggtcttgg agcaaaagaa atcgtagtaa actctttaaa
    11101 tatactatat ggtaatctaa ctgttgtctt accaacaata tttaatggag ttactgcata
    11161 tacattcttg atatttactg ctttatatac tccatgtata gctgcacttg caactatgaa
    11221 aaaagaatat ggcaataaaa tgatgtttac atcatttgca tatcaattta tactagcatg
    11281 gataatggct tttatagtta aaagtatagg tggagtacta tttatgggta attcaataat
    11341 ggaagctttg ataggtggaa taattatagt ccttgcactc tttattctgt ttaataaatt
    11401 caagtctaca aaaaacggaa atgtctgtag tggatgttct atttgttctg gatgtccaag
    11461 tgctaattct tgctcaagta aggaagacag caataaaaaa aataatgcac actaatatat
    11521 aaatatttta gtttaaaata agataaaagt gggtgtctca aaattaactt tttagttcat
    11581 gaggcactct tttttatata aaatcaaata tattttcatc atttcaacag taaaaaagag
    11641 cttatctagt aaaaaagagg cttatctcta ttttgagaca acctcttttt ttgttactta
    11701 ttcagtttct tgctacctaa cttcatgtgg aacctagtat cttttggaac acttgggtct
    11761 acacctctta atgtaggtat ttccccacat attagttgta taggtactat aaaattaaat
    11821 gtttgatagt aaggattatc tgtgatatca atctttaaat ttttatcatt ttctgtaaca
    11881 tctctaccta tagcaaatac attttccgtc caaccagaaa gtacatcaat catcttagtt
    11941 actctaggtt cttttcctgt atctagtata aatatagtag aatcactatt tatagcatta
    12001 tatataccat gtataaactc ttcaaactca tacccagtta caggtattct cattgtttcc
    12061 aataatttta atgctgcttc taatgtatct ccatatatat cagagtgacc tattattctt
    12121 atttctttag aattaactaa cttttctttg tttctttcaa tccattgttt agagagctta
    12181 tacactgctt caaatctatt aattgcgtct aatatcttat ttatttcctc attgtacttt
    12241 tcactagata ttataccttt ttctctagct atttgaagac ctaataacat taagtttaac
    12301 tttgtacaat aatatccttt tgttttagct ccagattttt cttcaccaca atttactgtt
    12361 aatatataat cagaaatctc atctattaaa gcattcttac aacctgccat agatgctatt
    12421 ttacagccct tatcttcagc taacttcata gcgttgtatg tagaataact actcccacct
    12481 tgagatacac ctactactag ggtattttca ttatcaaact tgaatgtatc ttcagttatc
    12541 ataaatggat acattttcac aacatctata tctaataaat tttgtaaata tggttgcacc
    12601 tgcactcctg agtgatagct agtacctgaa cctgttatta taatcttttt tagatttgtt
    12661 ctcttaactt cattaaataa gctatctgca ttagatataa tttctctcat tctaactggt
    12721 gtttctaaca tataatcttg tattgtcatt ttatacacct tccttatcta tatattcaat
    12781 aaattataat taatttctat aacaaaccta tagcatgtaa agcgattcct gttactatag
    12841 tgcctatagt taattttgtt acacttacct ttctctttaa catgtagtat attacaaatg
    12901 caaaggttaa aggtaacata ttaggtatta ttttatctag tatatcttgt aaaattactt
    12961 ctgcaccatt taagttgaat ttcagaggag tagttatact caacatagtt gcaaccattc
    13021 ctcctacaac gaataaacca acagttgtag ccatagacat tattttctcc ataagtccct
    13081 ctctttgtat tctttcaaga gaatttaccc ctacttgata accatactta agtccaaata
    13141 ttctaagggc aaatgctggt atattgtata atagtaagaa taatagtggt ccaaagatat
    13201 taccttcttt tgcaagtgat actcctactc ctgctgctat aatcctaaat gttccccaga
    13261 ataatgaatc accaattcct gcaagaggtc ccataagagc tgttttaaca gcactaattg
    13321 aactttcatc aaattctgga ttattagcat tctcttcttc catagcggct gttataccta
    13381 atatagcagg aactaccact gtcgttgtat taaaaatctc caaatgcctt tctattgctt
    13441 ttgcttgatt ttctttctta ttgtatagct tctttattgc aggtaacatt gaataacagt
    13501 aacctaagtt ttgcattctt tcgtaattaa atgcaccttg aagagcaaat gaacgccaaa
    13561 acatacttct taattctttt tttgttaatt tattcaaagt caatctctcc ttccgttaaa
    13621 gtattgattg ctaattgagg attttgatta ttttctttgt tattgatata aaagtttagt
    13681 acaaatgcta cacatactcc aaataaagct atagcagtta tatctaatcc accataagat
    13741 gctaacaaaa accctataaa gaaaaataca gacatctttt ttgaaagtaa catatccata
    13801 agcaatgcaa aacctactgc tggcaacaat gttcctgcaa cacccaatcc gtctaatata
    13861 actttaggta ttgcatttat taatgctgta actttatcag caccaatcat aattgctaaa
    13921 aaggttggaa ctgatgtact taaaaagaat aatattactg gcaaccacat cattatggta
    13981 actttcttaa aatcagcctg tttagcatag aaaactgcct tttgagaaaa gtacgaattt
    14041 attattctaa ctaatactcc aagagattgt gctaagactg ctactggtac tgctactgct
    14101 aaagcaactt ctgcaccatt acctgataat atagcaaaag ctgtacctaa tacacctcct
    14161 gttactacat ctggaggagt agctgcacct attcctgcaa ttcccatcca aattaattca
    14221 agctgtgcac caatcataat tcctgatttt atgtctccta aaactaatcc tactaacata
    14281 cctgtaacta ttggcctatc aagcatagat tgaccaaata tacgcccatc tagtatacca
    14341 actcctgcta taatagctaa catagtagct tgtactaaca tattgaacct ccattttaac
    14401 ttagtttaat ttacattaaa ttacattaca tttttgattt tgttttgatt ttctaataac
    14461 tcatttacat aaacaattcc attttttgct tcctctaatc ctgatttaac tattagtttt
    14521 gtatcctcct caactaataa aagtatagat aaaagcattg gtaaatttac tcctgtcaat
    14581 aattcaaatt tgaacccttg taaaagtaag tttgtacata tgtttgccac acttccacca
    14641 aacacatctg ttaagacaac aaattcttca ctatctttat tatttgataa tatacttcta
    14701 atttctttct cagcatcatc tgctgattta tccgttgtca tacaaaaata ctcaatatta
    14761 gttaatgaac caattattaa tttacttgtg tcaacaagct ctctggacaa ttctccatgt
    14821 gttgcaatta gaaatttttt cattctcttt ctcctaaatt attttattaa atctgatagt
    14881 tgtttctttt tgtctctagg taacattcta aattctatat caatccctaa atcacctatt
    14941 tgtttaaagt tatttatatc atcatcatca acagcaacta aatctgtaag tttcttcttc
    15001 ccttcctcat atcttaatcc tcctacattt atttctttta atactcctcc tgaattttta
    15061 gctacaacta aagcatcttt ggtatttttt actaacacta atacattgct tttctttgaa
    15121 gaagcaaatt tttctactat ttctccagat tcctctaccc cccttatata taaagttaca
    15181 ttgctaggtt tcgctaagtt cagtgacata gctttcattt ggtcattttt tgcttcatca
    15241 tttgcaacta gtattacatt tatacctagt gatgttgccc atccatatgc aacctgacca
    15301 tgtatcaatc tgtcatcaat tctcatcaaa gataccattt tccccaaatc ctccatcata
    15361 cattaaaatt tttattgttt atactctcat ttatctataa aagcaaaaag tatgccaaat
    15421 actggcatac ttttttaaat ttcattcact tattttgtaa tcttgtattt tactgtggta
    15481 gaccatagat aatattataa atatatccta tctctgaaat tggtatttgc acactataac
    15541 tcttttctag cacactaaat gcatttttta ttagttttac ttcactatga tggtttttga
    15601 ttaacaaatc catatcagta tactcttcaa tttcagtttg tctaactaat ctttcaatca
    15661 tacaacttaa gtgaacatat aaagaaatct ttttatcatt tgaaagtttt ttcttttgaa
    15721 tattttctat agcattaatt ccttcttcta ttctctctat tatctttttt gaatctaaaa
    15781 tagttagact atctattact ctaattaatg aaaaattctt tacaatagaa tcatttatgt
    15841 tctttatttt ttcattttct actactctgc taaatattct aaaaacatca tcttctcctt
    15901 ttcctgatat tatatcctct aataatataa aatctacccc attcacattt ggattggcag
    15961 ttcctactat agccatcaca tcatacattt caaaaactgg ttctttatct cccatagaaa
    16021 caagactatc ataatcataa ggtattattt tgacatcaac tattccaatt aaactttcgg
    16081 aaagtagatg ttggattttt atagcaatac ctatccctgt aaaacaagat gatattatag
    16141 catattcttt atttttttga ggataataca attgtatatt aggtttagtt tcttcatcca
    16201 taatttctgc aatctcttca atgtttttac cttgcattaa taaatttcct acttctagtg
    16261 cagaaatagt ggatatttgg tctataaata acattgggct atttatctta ttctttaaat
    16321 cttcatatat aagattaaga gagcccatat caaataatac aattaaacca ttctttatcc
    16381 tatctccctc tagatatcta gacatttgtt ttgatacatc agcaatagta gcatctatag
    16441 gcatatcaat agctgtaaat atatttttac ccaacatccg attacataca ttcgccatac
    16501 tactggcagt agcatatcca tgtgctataa tagtcgcatt aacttgatta aatttcattc
    16561 ttataattgt tgatttaata aatataatca ttatgattgt atctacatta ttaagataca
    16621 tatccaatct attcgttatt aatgttgata ttttacttat tatagagtat tctttgtaac
    16681 tctctttttt taaatatatt agtaatttat tttctaaagc tttatactca tcagacaatt
    16741 gataagattc gtccttcaaa taaagataag acgaaaatgc caatacatta ttcccatcat
    16801 attttatatt gttattaact tctaaatttc taaatatatc ctgcattatc gatattataa
    16861 gctccataag tacgttatta ttttcatcat tatttgaaaa gactaaattg tccattagtc
    16921 taatcattag attagaactc tttttactaa atttttcctt tgttatttca tttttttcta
    16981 gtctatcaaa gtaatctaaa cattttatga aactttgata gattatattt cttttatttc
    17041 ttccatttga catttcaata ctaaattgtt taggagaaaa gataatgctt ttgcttttac
    17101 cactttggaa ttgaaatata tctacatttt ctatataaag atttctagga aggtcttgaa
    17161 gagtaacaaa aatatttcca tttcttcttt gattttttgc ataagctcgt ccacatgcat
    17221 attttattac atttttacat tcacctatat tccccttgaa ttttatcttt aaaatcgcat
    17281 ttaatgtaat ttgagttatc tctataggca aaccaagtac cttactttct tcataaataa
    17341 aatgttctac aatctttctt ttttcaatag tccctctttc ttctatattg ggaacataaa
    17401 tatttatggg tattcttctt aaaaaggttt gtaaaaattc agatagactt tctgttgtag
    17461 caaatattaa tcttacccta gcttttctaa ttactccatt ctctccaatc ctagaaaacg
    17521 tacctgtatc cataaatgta aataactttt cctgaccttc actatttaat ctatggactt
    17581 catctaaaaa taaaacacca ccatctgatt gttctattag acctgctcta gattcatttg
    17641 ctccagtata tgctcctttt acatgcccaa ataatagact agacaataac tccaaattat
    17701 tataatactg cgcacagttt aacacattgt atggagaatt tttttctaat acattactgc
    17761 ttacactata tttgtatatt atcttggcta aaaaagtttt tcctactcca ctttcacctg
    17821 tcagcattat tgtaagtccg ccatttggat aaagtacagc ggtttttatt tgttcgatta
    17881 cttcttttaa gctattatca tatcctatga tactattaaa cacagtctct tgctttaata
    17941 atttacactc atttttaagt tcatctaaat tttcataaat actttttttt gtaggtccta
    18001 ctacatcatt tattttattt ttaggtaaaa aaataacagg tctactgttt atctttataa
    18061 gattatcaga ttttactaaa tcatttaata atctacttga ttgagttcta cttaaattaa
    18121 acttttttac tatatcttct gttattatgc cactttcttt tttaagttca tcaaagctgt
    18181 taaataatac acattcattt acaaaactta aaatttcatc cctcatgttc aacctccaat
    18241 acaaatatca ataatactat aatattagta tatcatttat atatttatga aaaagataat
    18301 tatattccta tcttgattct cttttgtaag gttgtaaaat caaacttttt ataagtataa
    18361 aatctagatt ttttaacata atctcaaggt tcttatcttt ccata
//
LOCUS       DAGQVA010000081        18048 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.081, whole genome shotgun sequence.
ACCESSION   DAGQVA010000081 DAGQVA010000000
VERSION     DAGQVA010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18048
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.081"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..382)
                     /locus_tag="MIV85_003066"
     CDS             complement(<1..382)
                     /locus_tag="MIV85_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962390.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEE"
     gene            734..1801
                     /locus_tag="MIV85_003067"
     CDS             734..1801
                     /locus_tag="MIV85_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBY2962391.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            1820..2980
                     /locus_tag="MIV85_003068"
     CDS             1820..2980
                     /locus_tag="MIV85_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBY2962392.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPISMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            2993..5089
                     /locus_tag="MIV85_003069"
     CDS             2993..5089
                     /locus_tag="MIV85_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBY2962393.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(5248..5592)
                     /locus_tag="MIV85_003070"
     CDS             complement(5248..5592)
                     /locus_tag="MIV85_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBY2962394.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            5884..6774
                     /locus_tag="MIV85_003071"
     CDS             5884..6774
                     /locus_tag="MIV85_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBY2962395.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            6992..8278
                     /locus_tag="MIV85_003072"
     CDS             6992..8278
                     /locus_tag="MIV85_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBY2962396.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(8367..8810)
                     /locus_tag="MIV85_003073"
     CDS             complement(8367..8810)
                     /locus_tag="MIV85_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBY2962397.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(8834..9628)
                     /locus_tag="MIV85_003074"
     CDS             complement(8834..9628)
                     /locus_tag="MIV85_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBY2962398.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(10194..10670)
                     /locus_tag="MIV85_003075"
     CDS             complement(10194..10670)
                     /locus_tag="MIV85_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBY2962399.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(10771..11940)
                     /locus_tag="MIV85_003076"
     CDS             complement(10771..11940)
                     /locus_tag="MIV85_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2962400.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLEKPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTNTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            12103..12966
                     /locus_tag="MIV85_003077"
     CDS             12103..12966
                     /locus_tag="MIV85_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBY2962401.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWGKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            13037..13630
                     /locus_tag="MIV85_003078"
     CDS             13037..13630
                     /locus_tag="MIV85_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBY2962402.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(13881..14516)
                     /locus_tag="MIV85_003079"
     CDS             complement(13881..14516)
                     /locus_tag="MIV85_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBY2962403.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(14596..15327)
                     /locus_tag="MIV85_003080"
     CDS             complement(14596..15327)
                     /locus_tag="MIV85_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBY2962404.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEGDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            15658..17847
                     /locus_tag="MIV85_003081"
     CDS             15658..17847
                     /locus_tag="MIV85_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBY2962405.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
BASE COUNT         6928 a         2076 c         2912 g         6132 t
ORIGIN      
        1 tttcttctga tgcatgatat atataatctt tggcatcctc actttctggt ttaagttcaa
       61 actctacaaa taaaattgaa ggtgtaaact cagttgtagg cattggagat actatctcgt
      121 aaaacatttc actctttgga aatttcatca taactctatc ttcttttcta atgactaaat
      181 catcagtatt attgtcatcc ataaacatat ataaaggagt gtctaaaact tcagcgattt
      241 ttctcaatga agacaaggat ggttcaatag catctctttc tatttgagag atataactta
      301 tagataaatc tgtcaatttg gaaacatcac ttaatgtttt tttcttgctt tttcttatat
      361 ttctcatctt ttcacctagc ataagaacct ccaaataata aaattaatat aaaatattcg
      421 cttaaaacaa agtaattata gcacaacata gaagtagtgg caataagaat acatagtaga
      481 ttttgacaat taaaatttaa ttaaatccaa ataaaagtct atgaaaatga attattgtta
      541 aattaataca aagaaaataa taataaaaaa atttaataga agagtattaa ttgaattaag
      601 attatcacat tatattttgg aaaagagtaa attttcagta aattatcttg acatatatat
      661 tgaagtaata atataattta aagtataaaa ttttaaaaat tgaattataa cttcaaaaaa
      721 taaggagggt aatatgaaga taacagatat caaatttgaa aagcttagaa ttaaattaaa
      781 aaaacctgta gtagtttcat ttggagtaat tgagtatgga gaaagtataa ttttaaaaat
      841 tgaaactgat gaagggtatt gtggatttgg cgaagcagca cctcttgcag cagttacagg
      901 tgaagttttg gataatgttc tttcagtatt gcttatgttt aaaaaagagt taataggcaa
      961 agacccacta gatattgaaa ccatacatac catcatggat ggaattatta taggtaatac
     1021 ttctgcaaaa gcagctattg acatagcttt atatgatatt aaaggaaaaa ttatgaatgc
     1081 acctctttat aaagttcttg gaggatttga tagtaaagtc caaacggata ttactataag
     1141 tatagataag ccagaaaaaa tggcagtaga agctttagaa agagtaaaag aaggttttag
     1201 gatattgaag cttaaagcag gtataaatcc tgaagacgat attgaagctg taaagttaat
     1261 tagagaagcc gttggagaga gtataagaat tagaattgat gcaaatcaag gatggaacgt
     1321 aaatagcagt ataaatacta tcaaaaagtt agaagaattt aatgttgatg caattgaaca
     1381 agcacttcca cattgggatt tagatggtac tgcttacata agaaataaaa gtaacacaaa
     1441 aattatgata gatgaatcat tacattcacc aatagatgca attaaggcta taaaaaagaa
     1501 tgcagttgat acatttaata ttaagctgat gaaatcaagt ggaatatatc ctgctataaa
     1561 aatcaacaac atagctgagg caagtggagt aaattgtatg ttaggatgta tgctggaaac
     1621 gagaattggt ataacagcag cagcaaattt aatagcatct aaaaagaaca taacagaagc
     1681 tgaccttgat agttttatgt tttgtgaaga attagaaggt atatctggag gatttgtaat
     1741 ggatggagat attatgaatc ttgtcaataa accaggttta ggaatagaag taaacttatg
     1801 ataaatttgg aggttaaata tgaatacact tttttcaaat ccaggtagta tacttgctgt
     1861 aatgacatca atgattgcat tgggttttta cttacaaaga tacaaagcca ttaaaagctt
     1921 aggaccagca cttacaataa tcataatggg aataatactt tcaaacttaa aagtagttcc
     1981 agtaagtact gagttatatg gaactatttc aacatatgct attccaattt ctatgactat
     2041 aatgttgatg agtgttgact taaaagaaat gacaaaatta tcaagagaac ctttaattgc
     2101 aatttttgta gctgtattaa ctgtaagtat catggcattt ttatttggat tagtatttgc
     2161 agaaaaaata tcagaaggtt ggaaggttgc tggaatgttt gtaggtacat atactggtgg
     2221 aagtgctaat cttacagcta ttggaacagg tcttaatgta agtagacaaa ctcttgcagc
     2281 agcaaatgca gcagactatg taattggagt accaacattg atatttatgt ttgctctacc
     2341 agcaatatta aaaaattcaa agaagtttaa aaaactttgg ccatatcatg tagaagaatc
     2401 agaattagaa gattgtcaaa atgaagaatt tatggagtca aaagaatgga gtattaaaga
     2461 tatagcttgg atgttggcta taggttttgt tgttacagaa gtttcaacaa tacttgctgg
     2521 atatttcaat tcaagtttta gtagtgcagc aagaatactt ttagttacaa caatttcaat
     2581 tataattgct caattaaagc cagtaaagaa actaaaggga aatttagatt taggattatt
     2641 tgttgcatta ttctttttat gtacaatagg tttttcagta gatataaaag agtttttagg
     2701 ttcaactttt actataacac tttactgttt tagtataatt tttgcttcat ttgttttcca
     2761 tttaggcata actagacttt taaagataaa gtatcaatat gtaatacttt ctatagtagg
     2821 agcaattgct gatggtccta cttcagcttt agtagctgct tctgcaaagt ggaattcgct
     2881 tgtaagtgta gcagtcgtaa tgggagtaat tggtggagta ttaggaaatt atgcaggtat
     2941 atcagtggca tatgcaataa agatgtctct aggattatag gggggagttt aattgataaa
     3001 atttaaatta tacatatctg gactatacag tggaaatgta atctttgatg gagatttatt
     3061 aattgaaaag ttgaatcctt ttacaaataa aatagaaagt ttaaaaccaa taagcaaaga
     3121 agaaaataca tattatttaa atcttacaaa aatagattta aagtctttat ttaataattt
     3181 tgatgtatat actaaaagct tagtaaacac agataaagac acagttataa ataacttagg
     3241 agaaacgcat tctaaactta atgaatatat atgggttcaa agaaacaaaa agttcccact
     3301 agatataatt attgtagata ataaaatagt aggttttatc tgtttatcta gagaaacttg
     3361 tactatatta attatggatg gatatgaaga gtatactgta ttaaaagaat gggaaaaaac
     3421 tcataaaaat gaagagatat attctataag atttggtgga aattatatga ttgatatgaa
     3481 agatggtata aaactttcta cagatgtata tctccctgat tttgtagatt ctgccaaaaa
     3541 agcaccgaca attcttatga gaactccata tggaaaagaa aatgataaag aaatatatta
     3601 taaatatgta caaagaggat atgctgttgt aatacaagat gttaggggaa gaaatgaatc
     3661 agaaggtaag tgggaaccta tgattcatga gagggaagat ggagatagta ccataaattg
     3721 gatagtatca caggaatggt caagtggaat agttggaatg cttggagcat catatcttgg
     3781 ttatgtccaa tgggcagctg catcttcagg caataagcat cttaaagctt tagttagtat
     3841 agtaacatca ggaagccctt ttattgatat accaagaaaa ggaggagctt ttgtatctgg
     3901 tatgcttgca tgggcattta tggtatcaag aaataaagtt gatagaagca aaatggtaag
     3961 agatgattgg gatgatgttt taaacatacg accaatagaa aatatacctg ttgaagctct
     4021 tggatataga attgaatttc tggaagaatg gttaaagaga gtagaaaaag atgagtattg
     4081 ggatttgatg gactggcatt tacaaaaaga taaaataaat gtacctgcat tggttgtatc
     4141 tgggtggtat gatgataata gtatgggaac tacagaggcc ttagatgtta taaaggacta
     4201 tgaaaaagga aagagaaagg ctattctagg tccatggatg cataattcaa atactttaag
     4261 agatataaat ggtatttctt taggaaatag ttcattaaga tatgatttgg attataatta
     4321 tctattatgg tttgataaat acttaaaagg tatagaaaat aacatagata cgactgctcc
     4381 agtagagtat tactctgtag gttctaataa gtggaagaca gaagaaaatt ggccaataat
     4441 aaataagata gataaaagta tgtatctaat aagtgatgga aatgctaaca catctttagg
     4501 aaatggtaga ttagtatttg ataatgattt agaagaaaag tatgatagtt atatatataa
     4561 tccaaaagac ccatcagtac aactaattga tatgtcagag aatgaagttg gagttccaaa
     4621 taactacaaa gatttagaaa aaagaagtga tatgttgtgt tatacatcag atgcttttag
     4681 tgaagaattt actgtaacag gtgatataaa gttagagttt tttgcatcaa gttctgccaa
     4741 agatactgac tgggttataa aaattatgga cgtggattta gatggaaatt caattaaatt
     4801 agctgatggt atacttagtg ctagatttag aaatagtttt tataagtcag agtttatgga
     4861 agaaggagag atttataagt ttacgattat aacttcaaaa atatcaaaca cgtttaaagt
     4921 tggtcataaa attagactag atataacgtc tagtgctaaa aactttattt tccaaaatag
     4981 caacacgaca gagggatata atagtattga atatatagaa gcaaagaata cgatttacca
     5041 tggaggtaaa tatccatcta aattgatatt gccaatagag aataagtaaa tttatataga
     5101 ttaaatagtg aggaggtgtc tcaaaatgaa ttttttagtt cgtgagacac tttcttttat
     5161 acgaaatcaa atatattttc atcatttcaa caatgaaaaa gaggcttatc tctctgtttt
     5221 gagatagcct cctataagct aaattgatta ttttgtagct gcaacaacgc tcatttcaac
     5281 taacaaatgc tctctagcaa gtctagcttc aacacaagct ctagcaggtt caaatccttt
     5341 ttcaacccaa gcatcccaaa cagagttcat agcttcaaag tctttcatat ctcttaaata
     5401 aatagtaaca gatagcaaat gttgcttatc tgaaccatat ttgtttaata aatcttctat
     5461 tttagctaaa acttcagttg tttgttcaat tactcctcct tcagcatgag tttgtccaca
     5521 taaataaact gtattgttat gaactacagc tctactcatt cttccagttc cttcatatct
     5581 ctttatttcc atattttaaa tacctccata gttaaaaaat ctattaaaaa tctaaataat
     5641 aaattaaaaa aagtctatac tatataaaat tatattatat attctgataa taatccataa
     5701 aaacatataa ctttttagct ataattatta ttgttattaa ttgaaaagat ttattagtta
     5761 cttgacatag tttacacttt taattatagt ataaattgga atatttagat aattattatt
     5821 taatgtataa gctaagtttt taattaatat ggctttatac atttatatag aaaagaggta
     5881 cgtatgagta gcacaatcaa atcaaatcga ataaaaggta taatgtttat aatagcatca
     5941 gcgcttggct ttgcaatgat gtctgcattc gtaaagctag ctggagattt accaagtttt
     6001 caaaaagtgt tctttagaaa tctggtatca gctataatag ctttttggct tatcataaaa
     6061 cataaaggaa gtctaactgg taaaaaagaa aatttaaaag tacttttata taggtcaata
     6121 tttggaactc taggagttat atttaactac tatgcaattg acaagttgat gctttcagat
     6181 gctaatatgc taaataaaat gagtcccttc cttgtagtaa tattttgtgc aattgctcta
     6241 aaagaaaaaa taaatgtaaa gcagatagga gctattataa ttgcatttat aggagcttta
     6301 ttcataataa aaccaacatt tagtgtagaa gtaattccat atcttggagg aattgcagga
     6361 gctgtatttg cagcaatggc atatacttgt ttaagagttc ttggagatag agaagattac
     6421 tatacaattg tatttttctt ttcagttttt tcattagtta ctgtagggcc aattgctttt
     6481 gcagtatatg aaccaatgac ccttatgcaa cttatatatc tattactagg tggagtattt
     6541 gcaagtctag gtcaatttgg aataactcta gcatataaat atgcacctgc taaggaaatc
     6601 tctatatttg actatagtaa tataatcttt tcagcaattt taagtatatt cttattcaat
     6661 gtctatccag atatgttaag tgttgttgga tatttaatag tattttcggc agcattttat
     6721 atgtttttat acaataagaa gttagataaa ttagacaaag aaaagaagaa gtaaactaga
     6781 taaaagtgtt tttataattt gtatttaata tttaagtctt tgtattaaaa ttaaagaaaa
     6841 tttaattaaa aatgtttggt atattaactt ataacagcag ttaaaattga aaaattataa
     6901 ctgctgtttc ttttattaaa aatatccaaa tgtctgtaaa aatagactat aatagagtag
     6961 tataaataat ataaagggga taaattaaag tatggaaaaa gtgaaagttg ctgtgattgg
     7021 agcaggtaat agaggaacgt atgcatatgc tccatatatt tatgaaaatt ctgatgtatg
     7081 tgaaatagtt gctgtagcag aacctaaaaa aggaagacga gaactattta cacaaaaata
     7141 taacctagat agtaaaaatg tatttgaaac tttagaagac ttttttaaac atgacaagat
     7201 ggcagatgca gtaataatag ctacaaatga tgatagacat tatgatgtag caaaactagc
     7261 tcttgaaaaa ggttatcatg tactattaga aaagccaatg tctaatagtt tagatggtct
     7321 ggtacatata gatgacttgt gtgataagta taaagataag atttttatga tttgccatgt
     7381 actgagatat tctccatttt ataataaatt aaaagaaatt gtagaaagca aaaaattagg
     7441 agagctagtt agtatacaat ataatgaaaa tataggatat tggcattttg cacatagctt
     7501 tactagaggg aattggagaa atagcaatga aaccagccct ttaattttag caaagagttg
     7561 tcatgacatg gatattttgt tatatttagt aggaagtaga tgcaaaaaaa tatctgcatt
     7621 tggaagctta aagcatctta ataaccaaaa tgctagtgga gagatggcac aaaattgtct
     7681 tcagtgttta gttgaaaaaa aatgtccata ttcagcaaag agaatttatt tagaaaaaga
     7741 tagaagtata aatagagctg ttcacataaa tccaactgaa gagaatctat tgaatatact
     7801 taagacaagt ccatatggaa gatgtgttta cagatgtgat aataatgttg tagacaatat
     7861 ggtaaatata ctacagtttg aaaatggagt gacggctact tttaatttat gtgcatttac
     7921 taaagaaaat ggaagaacta taaagttaat gtttagccat ggtgaagttg gtggggattt
     7981 aaataaaaat gagataagaa ttaaagaatt tggaaaaaac gaagaaatag ttatgaatcc
     8041 atcaaatcaa cagaatatgg tagaggaata tgatagaaat cttatagctg aatttattaa
     8101 attagtttca aataaagaac tagaaaaggg tagagtagca gcaaaagaag ctatacaaag
     8161 tcatgtaatg gcatttgcag cagaatattc tagggtcagt gatgaagtag tgtatataga
     8221 agaatttttt gatagtgcta agcaaatgac taaggagata gaagaaacta tattttaatt
     8281 aataaaaatt tattaaataa aataaagata gattaaataa tagaaatacg aaaatatgtg
     8341 ttctattaag gaatctatct tttttattaa ggttttttct tatccctatc aaaaaaatcc
     8401 atacattctg ataaaagata agaaagtaaa gcgaataaga tttctgtact taaaggaatc
     8461 gttactgaat ccataaaggt atcaattatg ttcatagcta gaaaagttag tataaaatca
     8521 attataaatt cgcaaagttt atatattgag tatggtaatt tgtttacata tctgaatata
     8581 tctaaaatag tagtgcatag aaaatcaatt ggagtggtta tacaaaaata tattaaaaag
     8641 aaaattaata cagctccaag agatttatat tcaaatccta agaatgataa gaagccaatt
     8701 cctataaccg tgaaaataca aaaagttata ccaaaaaaaa cagcaaaaaa taaaaataca
     8761 gaaataaatt cgcctaaagg aatccttctt ttattactta tcttaatcaa ctccttaatt
     8821 tatgatatga aatttatata aataataaca ttcttaaaaa ttcataatag tcctctgttt
     8881 caaatagtac tgtttgagaa tctatttttt tcatatttgg ataaaaagag gccttaaaag
     8941 ctttataatg ttctctaaat tttatttcta tcttaaattt atctggcaat tttattaagt
     9001 gcctagataa atctccagat aaagcttttt tgacaccttt ttcaattttt tttagtgcaa
     9061 ggtttggatg gattgaaatt gaaccatttc caattccttt tgacacagga acagtgacta
     9121 tatttggatt tagttttttt gcactctcac aaagcatttc atctccactt aaaaatgcta
     9181 caggaacatt ataatatgca gcaatataag catttatagt aaattcagat gctatttcat
     9241 catttatttt aaaatagtca taatcaatat ccatagtatg agaaagtgga ttaccattac
     9301 aagtagctcc agagtgatag ccggtgaata tacatgcatc aaagctttca tcaattcctg
     9361 ccatcataac tagtgggtct ttggtccatc ctctaagtat tttgacgttt tcaggtaaaa
     9421 tatttggatt aatatttcta ccactgtcat gtgcatcttt aacaagtatt tcatgtacac
     9481 cagattgagt agctccatca catgctgctg ttatctcttt actcatttgc gttctatagt
     9541 gttgcgaaaa ttcacattca agttttgttt catcccaatt tacaatacca caagtacctt
     9601 ctatatcagc acttaaatac aatttcataa tatatacccc cttatgttta ttattgatga
     9661 taataacaga taacagaaaa tacataatca ataaagggca taaaaatatt atgtcttact
     9721 attaactatt attaaatctg taactgaaaa ataactaaat tggtataaaa aaatataaca
     9781 ctatgtgtca tttatttata tagtttttta tatttgatgt ttatataaaa ttgtaacata
     9841 taagtggtta catttactag tttaacatag ttaaaatagt taggtattat ttttaagtta
     9901 aattgattat tataaaatcg cagaataaaa gaaaaattta atttattaaa atgcatgaaa
     9961 tgttttttcc tcaacataat gctaaattaa actcaaaaag aaataataga aaaatcttat
    10021 gtagcttaga aagaatgtga atgatttaag ggaaaaatag aaatttatta tataatatta
    10081 ggttgtatta tataatacag cctaatatta tatgtatatg tgacataaaa tcttggtaag
    10141 tgtaaataaa ataaatgtgg aaaacaagtt aatgaaatca agaaaaaagt aatttaaaat
    10201 tcaatttcat cttcccaatt aaattctcct gatttttcta cactcttagg ccagtgacta
    10261 caccatttag gaacggacgg attttcaacc ctatcaacgc ttggagtata tggctttaag
    10321 tcaataacag gactattatc attagcatca atatatggta tttttattat gccattttca
    10381 tggtcgatat tgataatttg tacagcagtc aatgctattg gattgggtct tataggtgac
    10441 cttgttgcaa atattcctat aacgtctggt ccacttttat aaggttttgg ggtttctaaa
    10501 atacttctta gttcaggatt atcaaaccca tcagcccacc aaaatacatt taaatgactg
    10561 aaatcgtcga gttcatttaa tgcaggtaca tactttttgt ctaatttaat aaagacctct
    10621 tcgccttgaa tacatatttt acctatagga tttattaata tttctttcat aatattacct
    10681 ccaactattt aatttatcat ttgtaatttt agggtataac atgacatcat gtgagggtca
    10741 atataaaata ataaataaaa atattaatag ttagaatgat aatacatttt ttacatggag
    10801 catgacacca gtaataaggc aatcttcgtc aatatcaaaa gtagaggtat gcaaagggga
    10861 agtaatgttt ttttcacgat ttgcacaacc aaggtggtaa aaagctcctt cacagtgtct
    10921 tagaaaatac gaaaagtctt cagcaccaag agtgggcgag tctttaagga taatattttc
    10981 ttcaccaaac aattctacag cattttgttt gacgtaatct actagatggt ttgaattgat
    11041 aagagctgga taaccttcct caatttcaac agaaatactt cctccaaatg ttttacaagt
    11101 aaaatcgcaa atttctctaa ttcgtttttt tgaaaactct ctagtttcag gagtcaaggt
    11161 tctcaaagta ccccttataa ccactttgtc acaaactata ttttctttga ttccaccttc
    11221 aatctttcct agagaaataa ccacagaatc agttggattt gtgtttcgac taacgattgt
    11281 ctgtagagct gtaataatat gagcagatat aacaatagca tcaatacctt gatgtggata
    11341 agctccatga cattttgaac catgtacagt taattgaagt gtattggtgg aagcatttag
    11401 agtgttgtat tttaattcaa ttagattttt gttgatattg ggatttacat ggagtccaaa
    11461 tatatatttt acatttggtt tttcaagaca tccatcttct atcataagtt gagccccacc
    11521 aatagtttcc tcagcaggtt gaaaaaagaa ttttacattt acatttaagt aatcctttaa
    11581 tttaaatagt atattacaag tacccagtaa aatagcagtg tgtgcatcat gaccacatgc
    11641 atgcattttg ccaatattaa tagatttata agaataatta agttcttctg ttataggtaa
    11701 ggcatctata tcagctctta tagcaactgt ttcaaagttt ggactcacgt taatgtatgc
    11761 agttatccct gtatgattct tatattcaat ataatttata cctatttcat ttaagtattt
    11821 aataattttt ttcttagttt gaaattcttc taatccaagt tctggagtct tatgtaaatc
    11881 tcttcttata tttataaccc aatcatttat ctcatgacaa agagttttta tattaagcat
    11941 aaaacacatc ctaactatat taaaaattta tttttcttca ttaattatat tattttatgt
    12001 aaatcattat tatgtatcaa gtacaaataa aatatcttat aattatatta gagatattta
    12061 gtatggagaa gaatatatca ttttataaga agaggtgttt aaatgttagg aataattgcg
    12121 ccatctgggc cattaagaaa tacaagtttg gaggaaataa agtttaattt agaaagttat
    12181 ggttacgaag ttaagttttc tgaaagttgt agtttaaatt ataaaggtta tttagctggt
    12241 aatgatgata ttagagcaag ggatatagaa gatatgtttt tagataaaga tgtagatata
    12301 attatgtgct taagaggagg ttatggaaca acaagaatat tggataaaat aaattatgat
    12361 ataataaagc aaaatccaaa accatttata ggtttttctg atataacagg tttaaattta
    12421 gctttctata aaaattgtgg tcttttacca tatcatggaa taatggcagc aaatgtaggt
    12481 aaatggggta aatttaccta taaatcattg gtaaatgctt tagaatttaa agatgaatta
    12541 tatttagaaa atccaaaaga agaaaagatt tatactgtat gtgaaggtaa agcagaggga
    12601 ataataatgg gaggaaattt atccttaata attgccacaa tgggaacaaa atatgaaata
    12661 gatgcaaaag ataaaatttt gtttattgag gaaattggag aacctcaata taaactggat
    12721 agaatgttaa cacaactata ttcttcagga aaacttgagg aatgtaatgg tataattttt
    12781 ggagatttta aggattgtat tgaagaaaat gatttgatgg aattactaat agaatttgca
    12841 aataaggtca ataaaccttc tatatataat cttcagtcag gacattgtat cccaatgata
    12901 actattcctt tgggcagaat gtgcgaatta gatgctacag aaaaaatcgt taaattaaaa
    12961 aaatagtgtg tatataaata taatagaaat atggtataat cttatacaag taaaaattta
    13021 gctaggagga tgaaaaatgt ctgatgatag aataatagac tttaacgaac taaagaacaa
    13081 agttaaagat tctgatgtag ataaatttga gcaatacata tataacttat atttttctgt
    13141 tatggatgga aagatgtcta tggctgagtt ttcaagaaaa atattcgatt atatgagaga
    13201 taacaacata tctcaagaaa aatttatgaa aatacaaaag caatttatgg agagatatgg
    13261 tatggacact gaagaagtag aaaaacaact tagaaacttt ggaatcgacc cttctacagc
    13321 aggttttatg agtaataata cttccagcaa agtatctaca gaagatttag agtcatttaa
    13381 gaagagtgca ggattttatg agaaatatgg agaaaaaatc caaccaaaga gttgtataac
    13441 aacatttata aaaaatgact taaatgatat taatgtaata atcgaccaag aaaagataat
    13501 gctttgtagt gatagaaaaa taaatcttat ggattcagaa ctaaatgagt ttttattaga
    13561 atataagaat atgtttaata aaaaaataaa ggtagtaatg tgcgaaacta cgaataagta
    13621 tgattattaa aaaatgaatt taaatactga agtagtataa attaattgta ctacttaaaa
    13681 ataaaaatcg caatttatta ttccttataa atttgtataa ggaatatcta aactgcgatt
    13741 ttttatattg tgaagattag taataataga tagtgtttta aattgtaatc ttctcactaa
    13801 aactgtgttt ttctattaga aattttatta aaaataaata tctgataatt gtattatatg
    13861 ggatgtaaag tattagaagc ttaacgaatc tcttttaata cattaactcc attttgaatc
    13921 atactgttga aaaatactaa gtttaaaatc tcagcagggt gaacgttagg aatatcataa
    13981 gtatctacta aattcatagg tacaactata tttttttcaa tattatgttg attaaaatat
    14041 gattttagag ttattgcaaa ttgatatata catatatctg tgcaatcgcc aactataatt
    14101 atattatcta tattatcaaa atccaaattt tctaatgcaa aaaatccatt agtagaattt
    14161 ttaggaagaa tttgtaggtt ttctatcgac ttaagttcat caaccaattc actttctaca
    14221 tcattttcca aacagtgaac aggataactc aaaagttcta ttgatttagg agtatgagaa
    14281 tcagtaaatg ctattactct atttaatttg tttgatattt tttttgtaaa catttcaatt
    14341 ggctttatta aagactctac tctaggagag tataatgcac cttgtcttgc aaagccatta
    14401 ttaacatcaa ttataaataa agcagtttta ctcaaatcat aattttctat tttttctatt
    14461 ggtagattat ctaaattact ctttaaagct tcaagttcat ttaataagtt atccatagtt
    14521 atacctccaa gataaattta ataaaattgt acatattaat tatataaaag tcaaggagta
    14581 caaactattg tataattagc tgtattgttt tgagtgtaaa agatttgaag caatatctgg
    14641 atagttagta aaaataccat ctacattgag ttttagacag tgtagtatat caccctcttc
    14701 atttacagta tatacattga caccaagtag atttttgtga caaagttcaa ttagagattc
    14761 atttactaaa actagaggtg gatgaagata actattaccc agaaatttag caaaattgac
    14821 tacattgttt ataggtaaat aacataataa tcctgttttt atactagggt ctaatttatg
    14881 aaagtttttt aaactattgc tgttgaaact agatataaga actctatttt tcatattata
    14941 ctttaaaata agctctaaaa cgtctttttc tatattggga tagtttattt tgtcagtttt
    15001 tagttctata tttaaaataa ggtctgtagg tgaaattaga attaatactt cttctaaagt
    15061 tggaatttta cattctttat tgctttgata tccttcaaaa gatgagttta gagtttttaa
    15121 ttttcttaaa gtaaagtctt ttacaaaacc atgtccatta aaagttctat caaccttttc
    15181 atcatgaata actacaattt ttccatcctt agttctgtgg acatcaagtt ctattccata
    15241 tatatccata tccaaacatt ttttaaaagc tagaatagta ttttctggat actttccact
    15301 aaacccccta tgagcataaa tattcattta tatggttccc tcctataagt ataacttatc
    15361 ttataaaaat ttaattaata taatatatca tattccaaaa ggtattgtta tatattagtt
    15421 aaataactat ttgtaattta tatattatat aaatgtagaa aaataaaatc atatatgtgt
    15481 tataatatat tttaaacatt gtaaatatta cgaatttagt agtcataata agtgtaattt
    15541 tatgcaagct catgttttta gagcttgcat atgtattatt aatatattta tatattgtga
    15601 aaataaaatt ccaaaagaat tttttctata gacttagtag taagggggaa ttttgatatg
    15661 tatgaagtta atttagaacg agctatgaat tattggatgg atttgttaga tgattatacg
    15721 aatatagcaa aaattccaaa tgattttttt tataaagatt gttctgatga agtagtagat
    15781 gaggttttta agatgaatat tgagaaacat gaaaggttaa ttcaatattc taaagtgaac
    15841 aatattagca tagactctat catagaaact atatatggcc ttatacttca aaagtatata
    15901 tatgaagatg atgtagtttt tggtaaaaca atgaatataa ttccaataag agtaagagtt
    15961 agacaaagtg aaaaatttat agatgttgta aggaagctaa aaaggcagtg gagcaggtct
    16021 ttagagtatg gatactattt gttatcagat atagagaata aaaatcatct aaatactaag
    16081 cttataaaca caatatttat agctaaaagt tttgatttat catatgatta tgacatagaa
    16141 aaaaaaggat atgatttatc tgtaatagta tatactaaga gggcacttaa aataaaaata
    16201 aagtataaac catctatata taaaagagaa actattagaa gaattttaaa tcaatttgat
    16261 tatataatag agcaaataat agaagataat gatattttaa tagaagattt agaatttgta
    16321 tgtaaggaag aagaaaaagt attattggaa gactttaata ataatcaata tgaaatacca
    16381 tatgataaaa gttatgttga tttatttagg gagcaagtta aggtaacacc tagtaatata
    16441 gctgctaggg atgaaaatag aaagttaaca tataaagaat tggatgaagt aactgataaa
    16501 cttgcaggtt atttaaatca tataggagtg gaaagtgaag acatagtagc tgtaatgtta
    16561 ccaagagata ttaacataat tattacagca atagggatta tgaaatcagg gggagcattt
    16621 tttccaatag acacaagtaa tccagaagaa agattgaatt accttcttga agatagtaat
    16681 gcaaaagtag tgataactac agatgaactc aaaagtaagg ttgtaaatga gaataccata
    16741 gtactcgata taaatgatga agaaatgttt aagcttggat atgaattaac tgaaaaaata
    16801 acatcatcaa attgtgcata tacgatatct acttcagggt caactggtag gccaaagacc
    16861 atagctatag aacataagag tttagtaaat atgtgttatt atagcgtaaa atctataagc
    16921 gctacagaaa atgatatatg tggtatatac ttaagtttca gttttgatgc tgtaatgaaa
    16981 caactattcc cttatttgct tgtaggtgca tcaatagata ttatgcctga agaagctaaa
    17041 tttgatgaat atacagtaaa tgaatactgt gaggaaaatg acataactat actagcattg
    17101 ccaacagcat ttgcaaggtt atttatacaa aattgcaata ataattcact tagagttgta
    17161 cagaccggag gagaaagatt aaaaggatat agaaagcgta attatgaact atataatgag
    17221 tatggaccaa ccgaatttac tgttgtatcg acttcttttc atgtggacag agaatatgga
    17281 aaaataccaa taggaaaacc tatatttaat acttatgcat atgtattaga taaaaagaac
    17341 aaactatgtc caattggagc accaggagag ctatgtctat caggcattca aatatcaaga
    17401 ggatatttaa ataaaaaagg gctaacagag caagtatttg tagagaatcc ttacaaaact
    17461 tgtgaacata ataagttaat gtatagaact ggtgatttag taagatggtt agatgatgga
    17521 aatttagatt atattggaag gatggacaat caggtaaaaa ttgatgagtt taggatagag
    17581 ctatatgaga ttgaaaatat aataaataat attacagaaa ttaaaagtgt tgtttgtata
    17641 tcgagaacaa atgatgatgg agatatgtat atatgtgcat attatgtaat tgatgaggaa
    17701 gatagtggta agataaatga aagaactatt agagaatatt taaatgagca tctacctcca
    17761 tatatgattc caacaataat aatgaggata gataagatac cagttacacc aatcggaaaa
    17821 gtaaataaaa gagcattacc agaataattt tttattatga taggtgtcat aaagtgattt
    17881 cagacatttc tttatgacac ttatttttat aaaagaatca atttgcataa aaacaagaat
    17941 tttctgtata tatttactat ggtgaaaatt tatttataag aatgattatt gtatttttta
    18001 tacttttccg tgttttaaag catttttttt acaaaattaa ttttacat
//
LOCUS       DAGQVA010000082        17767 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.082, whole genome shotgun sequence.
ACCESSION   DAGQVA010000082 DAGQVA010000000
VERSION     DAGQVA010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17767
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.082"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            45..914
                     /locus_tag="MIV85_003082"
     CDS             45..914
                     /locus_tag="MIV85_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBY2962406.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
     gene            1789..2496
                     /locus_tag="MIV85_003083"
     CDS             1789..2496
                     /locus_tag="MIV85_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBY2962407.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            3095..3595
                     /locus_tag="MIV85_003084"
     CDS             3095..3595
                     /locus_tag="MIV85_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962408.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSNLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3845..4624)
                     /locus_tag="MIV85_003085"
     CDS             complement(3845..4624)
                     /locus_tag="MIV85_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962409.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(4621..5100)
                     /locus_tag="MIV85_003086"
     CDS             complement(4621..5100)
                     /locus_tag="MIV85_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2962410.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            6086..7093
                     /locus_tag="MIV85_003087"
     CDS             6086..7093
                     /locus_tag="MIV85_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBY2962411.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            7131..8558
                     /locus_tag="MIV85_003088"
     CDS             7131..8558
                     /locus_tag="MIV85_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBY2962412.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTKKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SAGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQMYMGVEE"
     gene            8700..9965
                     /locus_tag="MIV85_003089"
     CDS             8700..9965
                     /locus_tag="MIV85_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2962413.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            10007..11605
                     /locus_tag="MIV85_003090"
     CDS             10007..11605
                     /locus_tag="MIV85_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBY2962414.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            11640..12662
                     /locus_tag="MIV85_003091"
     CDS             11640..12662
                     /locus_tag="MIV85_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBY2962415.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(13050..14453)
                     /locus_tag="MIV85_003092"
     CDS             complement(13050..14453)
                     /locus_tag="MIV85_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2962416.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            15320..15829
                     /locus_tag="MIV85_003093"
     CDS             15320..15829
                     /locus_tag="MIV85_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBY2962417.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            15857..16051
                     /gene="rpmI"
                     /locus_tag="MIV85_003094"
     CDS             15857..16051
                     /gene="rpmI"
                     /locus_tag="MIV85_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBY2962418.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            16107..16463
                     /gene="rplT"
                     /locus_tag="MIV85_003095"
     CDS             16107..16463
                     /gene="rplT"
                     /locus_tag="MIV85_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBY2962419.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            16773..17318
                     /locus_tag="MIV85_003096"
     CDS             16773..17318
                     /locus_tag="MIV85_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962420.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            17305..17469
                     /locus_tag="MIV85_003097"
     CDS             17305..17469
                     /locus_tag="MIV85_003097"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962421.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLLGLYFIVSFHLS
                     NDLEWYNEVF"
BASE COUNT         6613 a         1977 c         3020 g         6157 t
ORIGIN      
        1 aatttctata ttaatatgta gtaattcaat attattataa aggagtggtt attattaagg
       61 caattgaact ttataaaaaa ttagatttag aatttaatat taaaaatatt aatgatgatt
      121 ggagttttat gaattttgaa aatgatttta ttactccaga atttagaaaa aaatacatag
      181 gattagtatt agataatgct caaaatatta ataaagtata cacaactact tttcctgata
      241 aagaaataat taagcaagtt atagataaag atgaaaaaga tattttaatt ttttcacatc
      301 atgcaatggg atacatagca tcagatgaag gttttccatt tcacgacata ccactatctt
      361 atatggaaga gatgaaaaat cgtagaattt ctttttatgt attacattct ccactagaca
      421 actatagtga ctattcaact tctgttagtt ttgcaaaagc tatgggttta gaaatagtca
      481 aaccattttg taaatatgac gataaaattg aagtaggagt tatatgtaaa acatcactaa
      541 aatcaataga agagattaag gaattaatta aaaaatctgt tggtcatgat gtgaaattgt
      601 atgattatgg agattctgta ttaaaagatg gtttagttgc tattgcagca gggggaggaa
      661 gttatccatt tgtagcaaga gaagttgctg aacttggtat aaatctatat attactgggt
      721 ttactaagcc tttaaaacat tttgaaccag tattagagtt ccatcaaata gcaaaagata
      781 atttaattaa tgttataggt gctactcatt attctacaga aaaatttgcg tgtatgggca
      841 tggtcgatta ttttaaaaat ctaggtttag aatcagaatt tttgcaagga aagtattact
      901 tagaggattt ataggacata ttaaacaata aaaataaaca gttagtaaaa atttatttta
      961 ctaactgttt atttttttac ctatttatcc agtgttttga aaaaatctat ctttattttt
     1021 taaactaaga aaatagactt ttaattgctg attagaagat ttagttttga tgtcttttaa
     1081 attatttttc gatatttttt agtttatttt ttgatgtatt ttagattatt atttaggatt
     1141 gattagaatt tataaatatt tattttagat tattataaat atttatttta aaaaaataga
     1201 attattatat ttatgataat aaatggtata ataaaaggta aagtgtcaaa tatgcactaa
     1261 attaaataag ttaattagta tataggttaa agtggaagta attaaaactt attaagtatt
     1321 agaaaatgac ttcttattag agtaagtatc taaaatgata taaaaattat gattactcat
     1381 taaagtgact attatagagt ggataagatt actcattaaa gcgattactg tggagtagat
     1441 aaaattactc actaaaataa ctatcataga gtggataaga ttactcatta aagcgattac
     1501 tgtagagtag ataaaattac tcactaaaat aattatcata gagtggataa gattactcat
     1561 taaagcgatt gctgtggagt agataaaatt actcactaaa ataactatca cagtagataa
     1621 gattattcat taaagttact atcacagagt ggataaaatt acacattaaa attgtctgtt
     1681 aaagaatgaa taaaaaagag attgctcaat ataagaagca tataaaaaat aaaaaatcaa
     1741 acgtataaaa tttaataaat aataactgat agggaaagga aagatagaat gatatttaca
     1801 aaaagtaata aatacgataa ggactttctc atgaaaaata tgatgggacc taattgtata
     1861 aaaatattgg aagaattaac aagtaagata aaactagaaa agggaatgcg tattttagac
     1921 ttaggttgtg gtaaaggtat atcttcgata tttttagcaa aggaatttga tgctactgta
     1981 tttgcaacag atttatggat agaaccaact gaaaactata aaagatttaa agagtttaaa
     2041 ttggatgata aaatatttcc aatacaggca gaggcacatg aactacctta tgcagaaggt
     2101 ttctttgatg cggtgataag tatcgattct tatcactatt ttggaaacaa agaaggattt
     2161 ttagacaatc atatatcacc tcttgtaaaa gaggggggaa tacttgctat ggcaatgcct
     2221 ggattaaaag aagatttcgt ggattgtata ccagatgaac tcattccatt ttggcaagat
     2281 aatatgaact tccattcaat tacatggtgg aataaacttt ggtctgaatc ggagtctgtg
     2341 attgtagaga aatgtgaagc tttaaattgt catgatgaag cttggaagga ttggataaat
     2401 tgtgataatt catatgctat aaatgacaaa aaaatgatgg aagtagagaa tggaaagtat
     2461 tttaatacaa tttctttgat agcgagaact aaataattgt gatgaattta taaaagtata
     2521 agataagtag aaatataagt tgaatgagag tataagaagc atagaaatat aagttgaatt
     2581 aaagtagaag gtaaataaaa atgtaagtta aataaagagt ttatacaaaa atgatttttt
     2641 agattattta tacccaatcg agttgcttag gtcagttggg tatttttatt ttttaaagtt
     2701 aaattgcaaa tactattgtg tgatatatat tttaatacta aatgtttgtt ttataagaaa
     2761 taaactaata gaaaaaatag ttttaacaat gaaagcaaaa aaggtattga tgaagattaa
     2821 aaattttata gtaccatttt atatatttta ttatacttta aatcaaattt caaaatgatt
     2881 aagtatatat acccaaaaga ttaaagaact atatttatta tactattaaa aattatttta
     2941 atagagatac aagagataga tatattggtt ttaattttat agaaatatac aaagatattt
     3001 taagctaata tatagtaatt tatatagcat tataaaatag aatcatataa aataagttaa
     3061 ctacaatcaa aaattaaaaa ggggaaatgt taagttgata gaaggcataa aatttataaa
     3121 ggcagaagaa aagtatattt attcgtattg gcaaactttt gataaaatag caaaagagag
     3181 gaaatatcta gctatggatg aagcctttcc ttttgaagaa acagttgaat ttataaaaaa
     3241 tattataaat aaaaacttac cacaactgtt tataattgat ttagaatcag ataactgtat
     3301 tggttggtgt gacgttttac ctaaaactga aaaagttggt tatttaggca tgggtattct
     3361 taaagagtat agggaaaaag gtatcggaag taatctttta aaacaaatta ttgatttatc
     3421 aaaagaatat gggtatgaaa aaattgagct tgatgtattt aaaagtaata gtagagctat
     3481 tcatgtttat aaatctttag ggtttgtaga ggtaaataca atatctagtg gttttacatg
     3541 gaatgataga cctgtaaaag aagaagtaat tcaaatggag cttacactta tataaaataa
     3601 agttaaagtc tttaaaattc catatacact tgtataaaat aaagttaaag cccttaaaat
     3661 tccatataaa agaaatattt ttaagggctt tttaataatg cttcttttga aggtagctaa
     3721 atatctaaaa ttttatatat taaatttaaa gaaaatataa agatggaaga tacaaccatg
     3781 tttactaata aaaaaattaa agtcataaat aataaactca taaacaactt attattactt
     3841 atgtttattt tgcatctatt acttcatgag ccattttaac taagtcattc atagataaat
     3901 ttgagtcttg aactgtaaaa gaatagtaaa ctccatcttg tttccatgtc aaaaacttaa
     3961 atttattaac ttcaactttg tctgattcat tatttggccc tacactaaat gtgtatttgc
     4021 ctgatttttc atcaatttta tcctgttctg tcattttata accttctggt acaaactttt
     4081 gtgcgaatgc ttcataagaa atattaatat ctttgtaagt atctacaact tttagattgt
     4141 cagaactctt cccaagtaca ttatttgctg tgtcaagaga tatttcatca ttgccatttt
     4201 tatattcaaa actaagtgct tttgattttc ctaaaacatt attttctttg tcaaatgctt
     4261 ttttatttac agtatatgct cctttaaatt tatatccatt actaaattca gaaactatat
     4321 taggggtaaa gttaaagtct ttttttactt gttctgtagt tgggatagat gtataggtag
     4381 ccttagtact tgattttcca accaaactat atatatgtcc tactgcaagg gctgttgtgc
     4441 tcaatatcaa agtaatggct aaagttgcaa ctaagccttt tctaaatggt aatttgtgtg
     4501 ttttattatt aatcatttta taattttcct ctctttctgg taaactattt agtgttttgc
     4561 ttaaactatt atgaaaactt tctggaactt ctggaaacga attatttaat atatttttat
     4621 tcatatgatt acctccgtgt tttctaattt agtttttaat aatcttcttc ctcttgataa
     4681 tctacttttt acagttcctt gaggtatatc taatatttcc ttaacttcat ctactgaata
     4741 accttcaata tagtaaagga ctattggaat tttaattttt ttaggtagac tttgaatagc
     4801 agtatacaaa tcgctatagt catctttttc atcaattttt ttgtttttga agacatcttc
     4861 aaatgataga gattttaatc gtttgcgtct taatgaatta cattcattta tgactattct
     4921 aatcagccat gttttaaagt attgttcttc cttaagagaa tccaactttt catatgcttt
     4981 taaaatagca ttgttgacgg catcttcaca gtcttggtcg tttcctagaa tagacttaga
     5041 tactcgatac aaagtctgtt ctgattcaag tatattgttt gtaaatgtag ttttatccaa
     5101 ctaagttcct tcccttctat gcaaatcgta gcgctacttt tttgtctttc acttattaga
     5161 taaaatttta ctatagatgg ttcacttttt ttatgattat ttgataaatt taagtttgaa
     5221 agttttgcct attctataca aatattctat aatatatttt ttctagtatt ttcccctcat
     5281 atataaagcc atgtagatat attaaacttt agaagccatt tatatattta gttttatagt
     5341 aagtctttat attgagtaat tagaaaatag taagtattta atgttgagta gttagaataa
     5401 caatgctttt ggattattta cttcatgtac agatttaaaa taagttcttt aaatagcaac
     5461 tttttgaaaa aacgcaaaaa tattttatgt tgtctgatta tatttataga tgtgaaacaa
     5521 tattgtatag agtaaaagta tatagaagat gattacatag agtttatact tgaattttac
     5581 aaatataatt atcaaaatac tgtcaaagag aaaaatagtt ttgatgaacg tttttatcaa
     5641 attgctacag agacagggct aagtgctaat actgtatata aagtattcaa taaaataata
     5701 aatagtggaa aaactgaatt tacatcaaag gaattagcta ctatatgtgg tgtaagtatt
     5761 agaactatgg acaggattat acttagattg tgtgattctg gttattgtga ggtagtgagt
     5821 gaacagctta tgagcaagta tggtagaccc agtagaatat tacgttttaa accttttctg
     5881 ttgttttaaa tagatataag tcaaaaatta aatttttatg ataacatttt ctttacaatt
     5941 ttttagatat atgttaatat ttagaaaaat gcatatgtat tcataaaata aacttaaaac
     6001 agctaaaaaa tcattaaaaa ggaaatcgta tgcatgaaat gagaaagtta atttataact
     6061 taaataaatc tgggaggaga taattatggg aaaatatcag gattcaaaaa aagttgtaag
     6121 aaattatttt gaagcattag aaaatgctac tggggatgag gttgaaaatg tcttaaagca
     6181 acatatgaaa tcagattata actggaaagg tgtgtatcca tttcgtgaac aagaaggcac
     6241 tgaaaatgta gcagatgtat tttggaagcc tttaaaaaaa tcattgagta atatgcaaag
     6301 acgacaagat attttcattg caggaacaaa tgagattgac aatagtgaat gggtaatgag
     6361 tatggggcat tttatgggac tttttgataa cgattggctt ggcattaaac atactcgtaa
     6421 aatgattagt ttaagatatg cagaatttaa ctgtgttcaa gatggtaaaa ttgctaaaac
     6481 tggattattt gtagatataa ttgggtttat gattcaagca ggagttaatc cattgccacc
     6541 acaaacaggt tcatattttg tatatccagg gccaattgac cataatggat tactttttga
     6601 agatgcagat gaagttgaag gagtaaaaac tttagcatta gtaaataaaa tggtagatga
     6661 tttatctgaa ttaaatgaaa gtggtgctat gggatgccca ccagaaatac ttgaaaaatc
     6721 ttgggctaaa gatatgattt ggtatggtcc aggtggaatt ggtgcttctt atactatacc
     6781 tagatatcaa gagcaacacc agctaccatt tagaaataat ttaaaaggaa agactttcaa
     6841 tgggcatgta tgtagatttg cagaaggtaa ttttgcttgt ttctttggat ggcctaatct
     6901 gactaatgta ccatgtggag gttttttagg attaccaggt ggagaggtta aagcagatat
     6961 gcaagttgtt gatgtttatt atcgtaaggg cgataaactt caagaaaact gggtgttaat
     7021 tgatattcct tattggttga aacaacaagg gcttgatatt cttgagagaa ctaaaagtat
     7081 ttttaatgct tagttatgca tacgtattct aaaataaagg gggatataaa gtggcatcta
     7141 ccaacaaaaa taatgcaaca agtaaagaag aagaaaaaga agtttctaca agtgggcttg
     7201 aatcatgtac ggttaaagaa aacaaagcta aaatgaatca aactaatttt agtaatataa
     7261 atgaaaatca aacaaatgag aataaaacga acacatataa aagaaatata gataaaggaa
     7321 atatagataa agggaatata gataaaacaa acacaaataa atccgacata aataaagtta
     7381 acatagatac agtggataca gataaattaa atacaaatac tcttactaaa aaaaataaaa
     7441 aagttatatt taagggggaa gataatatgt catctacaaa aatttactat ggagattcat
     7501 tagaagtaac gcctgttgga gtaatggatt acaatgattt ttcaaaacag acaaaaaggg
     7561 aacaggaaat acctggattt gattctaagt atagagattt tgtagattat attatgaaga
     7621 ttacacataa tatctgggaa gaaaaaggta taggtgttat ttatgataca tatcacaata
     7681 atgttacaat gcattgtggc tcttcaaatt tagttggtat taaagatgtt atttccaata
     7741 ctcttcaaac attacatgcg tttcctgata gaagattaat tggtcaaaat gtaatatggt
     7801 ctaactttgg tgctgatggt tttttatctt ctcaccgtgt tttgtctaca gcaactaact
     7861 taggtgatag taattttgga ccagcaacag gtagaaaaat aaactttaga actgtaattg
     7921 attgtgccac aactaacaat agaatccacg aagaatggtt ggttagagat aatttatgga
     7981 ttgttactca attaggatta aaccctcagg aagtagcaaa gagtatggca aaggcaagtg
     8041 aatctaaagt gcttagttta caatcaactt atggtatctg tgaatctatg gatggtcaat
     8101 ttatgccaac taagtatcaa gcaaaagatg attctgctgg cgaaatgatg cttgaaatga
     8161 caagccgtat ttataattat aaatatataa atgaagttaa aaaatactat catgataatg
     8221 cagtagtaca ttttatatgt gataaagatt taaatggtta tgatgagatt caaggaatga
     8281 ttgtaagttt acttgcatca attccaaatg gaagttatga agtggaaaga gtaacttgta
     8341 atcaaagaga aaaaaatgaa ggttatgatg tatctgtaag atggagatta cgtggaataa
     8401 atgaaggtat aggatttttt ggacagcctt ctggaaagca tatagaagta atgggaatca
     8461 atcattatca tatactacaa ggtaaagtaa aggaggagtg gataactttt gatggtatgg
     8521 atgtattaaa acaaatgtat atgggagtag aagaataaag ctgtttagag tataaatagt
     8581 tttgaaatat atagggaagt attgctttat aaaatttaag tggggaatgt atatgaaaaa
     8641 tagatgttta aacttttagc aaaattatga ctaaatttaa aagggggaat tataaaaata
     8701 tgaaaacaac ggttgaaata gaaaatgata tcatattagg aaaagactat tcaaacctaa
     8761 aaagaggaat tgcatttttt tcaattgctt taatatactt tttttattgc tacaatttta
     8821 tggtgggtac ttttattaaa ccaacaatga tttatgcttt agcagatggg ggatttggtt
     8881 tttcattaaa acaaacagaa gaaatatttg cagttatgtc ttttggtaca attccaggta
     8941 catttatttt tggggtgatt tctacaaaaa ttgggaagaa gaggacttta attagcgttg
     9001 ctttactgat tggattgaca acatttatac caatgttatc tcctacaaat attatgttat
     9061 ggaaaatagc acgtttgtgt acaggagtag tgttgggagg cgtatttgga acagctatgc
     9121 ctttagttgc agatatgttt ccaagtaaat atcgtggtaa gttagctgct atattaactg
     9181 ctttattttc attagcaatg atttttggtg ggaaagtata tggcgtttta ggtgatgcaa
     9241 attggcaaat attgatgtat actgcgatta taccacctat agttggagct atcttagcaa
     9301 ttttctttgt gccagatgat ttggagtata caaaggaatt agttaaaaag ggaaaagaaa
     9361 ctggtgaaaa gattagctat ataagtatgt ataagggaaa atacttatgg attggattgg
     9421 gaacgattct tttatcaggt gcaaatttta cagcatattc agcattttca aataatgcaa
     9481 ctacatacct agtgacagga ataggaatgt cagcagcagt ggctgggtct atatatagtt
     9541 tacaaggaat tggtcaatta gtaggatatt tattctgggg ttcaattgca gataaatttg
     9601 gaagaaaaat accttttata ggtatggcat tagcagcagt atttgttttt atatatacaa
     9661 aattaggtgg agataataca acaacattct atatgatatc agtattacta ggtgttgctg
     9721 ttggatattc tggagcatgg ggagcatact acacagagtt gttcccaagt aaatatcgtt
     9781 cgttgtcatc tggtatgtca tttaatggag gaaggattat atctacgttt gcaatacctg
     9841 ctatagctgg tacagcttct ggtactttag gtatgatgac tatcttttac atatcaatcg
     9901 cagtctttgt agcaggtgct attgtatggt tattcttacc ggagacgtta aataataaaa
     9961 aataaaatac taggaattta ttttgttact tagaaagggg tggcttatga tttcatcaat
    10021 tgatgtatgt attataatag gatatttgct attaatgtta gttattggtt attattcagg
    10081 aaaagataat aaaaatcaag aagattattt cttggcaggt aggtcaatgc catggattcc
    10141 aattgcttta tcagttgcag ctactatgat tagtgcaaat ggctttatag gtggtcctgg
    10201 atgggcatat gtagatggaa tgtatccagt aatggttaat attacagtac ctttagcaat
    10261 attttttgca ctgagcatta ccaccccagt tatctataaa ttaaaaataa cctctatata
    10321 tgaatatatg ggacttcgtt taggaaatta ttcaagagga ttaactatta ttcaattttt
    10381 tattaattca ttgattcaag ctagttctat ggtatatatt ccagtgctta ttattcaaat
    10441 gattactggc tggtcacttt atgctttagt cccaatagtt gtacttgtat caattatata
    10501 tactctatta ggtgggatta aggcagttat atggactgat agtattcaaa tgatagtagt
    10561 aataagtgct gtatttatag taattattgt agccttaaaa ggaatgaatc taagtttctt
    10621 tgatacatta caaattgcac aacagagtgg aaaattaaat acatttgatt tcagtaggga
    10681 tatttcagtg acaaatactt tttgggctac tttaattggt ggaactgtaa tgtggataag
    10741 atacttttgt tttgaccaat ctcaagtaca aagagtttta acatctaaat ctttaaaatg
    10801 tgcaaaaaat tcttttgtag ttagtgcatt tgttatgaat ttagtttact actttatgct
    10861 attggtagga gtaattttat ttgtttttta tgggggaagg acatttgaaa cttcaaatga
    10921 aataatgatt acttttattt taaatgaact tccagtagga gccattggaa ttattattgc
    10981 aggtgtgttt gcagcagcaa tgtctagtat cgactctata ttaaacagta tgacaactgt
    11041 ttttacgaag gatatttatg agttttattt caaaaaagac aacaaagaat catcattaaa
    11101 agttacaatg attataactg tagttatagg agttgttatg acaggtttta ttattatggg
    11161 atttggagga agcatcaaat caattcttga ccttgttggt aactatatct catactttgc
    11221 tggaccagct acaggtgcat ttgtactagc aatgtttaca tataaagcta atgataaagg
    11281 agtatctatt ggttttattg tagggttagt tttaggattt tttatttcta ataaatataa
    11341 tgtgagttgg ttgtggaatc cagcaatagg tgctacaata acattgatat ttggatatat
    11401 ttttagtgtc attttaaaga aaaatcataa tgcagatgat attaaaaaat acactgcatt
    11461 tggtatgaga aatcacctta tttctcaagg aatggataaa gtagatggag tatctatagt
    11521 gccattttct ttaggtaaac aagaactaat tgtattagct ttttttatta tccaatatat
    11581 tatattattt ttgatacaat tttaagaaga aatactagat atttaaggag aaatactaaa
    11641 tgaatcaaaa gaaagttcat tataataaat cggctacctc aaaagatgtt gcaagattgg
    11701 caggagtatc tcaatcatct gtttcaagag catttggtag tgcaaatgga aagggcgtaa
    11761 aacctgaagt aagagaaaga atttttcgtg tagcaaacga aataggatat gttcctaatt
    11821 tggtagcacg gggaatgatt agtggaaaaa ctaatgttat aggattgata gttggtgata
    11881 gtctaggtcc attttacaat agaattatca atttatttgt agaaaaaatt caagagatag
    11941 gtaaacagtg tctcgttttt aaagttccta gacaacaaag tatagatagt ataatttcaa
    12001 aagtaattca gtttcaagta gaagctgtga ttattacagc ttcggccatg aataaggtga
    12061 tggctgagac ttgtgaagaa aacaatattc ctgtgattct ttttaatcgt tttatacctg
    12121 gtataaaaat aagtacagtc tatgtagacc caattgaagg tgggggaatg gctgctgaat
    12181 atctgcttaa gaaaggtcat aagaatatag gatatattca atttacgaga gaaacaagtg
    12241 aagaaatgga aaagaaaatt ggattttatt ctaagttaag acaaagtggg attcataacc
    12301 ttaaagaaga atctgcaaac tatgattatg attctggata tgaagcaggt aagagaatgt
    12361 tagcattatc aaatcctcca acagcaattt tttgcacaag tgacttgata gctattggtg
    12421 taatggatgc tgcaaggttt gagtacaagt tgagggtgcc agaggattta tcagtgatag
    12481 gatatgatga tattcaaatg gcttcatgga agagttataa tttaacgacg attagacagc
    12541 cactagattt gttgattgaa aaaacaatta acatacttaa gtccttatta aatgaagaaa
    12601 atccagagtc agttgttgaa atgttaaaac ctgaattgat tgaaagaggt tctacacttt
    12661 aagtggtaga tatttaatta agtggtagat acctaattaa gttgtagata tctgataaga
    12721 aatttttaag ttttcaatcg ttctaaattg tgagtataaa aatctactaa atttagttat
    12781 gtaaaatata aattataagt gtagaaacta ggctactagc ttttatacca cttcaaacat
    12841 tactggaggt agttaagttt acatcagttt agttttatgt agatataata ttctgtaaat
    12901 agacaaaatt aaaatatgta agtgtctcaa aatgaaattt ttagtttatg aggcactttt
    12961 ttgtataaaa tcaaatgtat ttttataact ttaacaataa aaagaggctt atctctattt
    13021 tgagacagcc tcaaattttt aaaactatat tagtttacag cttcttttcc tatcaaatct
    13081 tttaactctt catgagtcat agtttctttt tcaaataaga atttagaaac agaatgtaaa
    13141 tcttcaagat tatcctttaa catctctaaa gtctctttat aacaaatttc aactatacga
    13201 tttgcttcct tttgaacctt atcacataag aaagtcttat catttccatc aatagtcata
    13261 aatcctaagt tactcatacc atattcacaa accatttggt tagctatttc agtgactttc
    13321 tttaagtcgt cctttgcacc agtagattta tgattaaata ttaattcttc tgaagccttt
    13381 ccagcaagta atatttttat ttttccaatc aactcatcct tagtataaat atatctatct
    13441 tcatcaggta attgaagaac ataacctaat gcttgtcctc taggaactat agatattttt
    13501 tgtataggac aaattcctac tatatcactt acaagagcat gtccagcttc atgatatgct
    13561 actatttttt tctctttttc aaccaatgca gagtttttag attctagccc tgcaataact
    13621 ctttcaagtg ccttgtcaaa atgttctgat gtaatacact cactgtcatc tctaactgca
    13681 aatatagctg cttcatttgc tatatttgaa agatgagccc cattgaaacc atgagttttt
    13741 ttagctaaaa gttctagatt tacagatttg tctataggtt tgtcatctgt atgtaccttt
    13801 agaatttcaa atctagtgtg atagtttggt gcacctatat gaatgtgtct gtcaaatctt
    13861 cctggtctaa gtaaagcttc atctaataag tcaagtctat tggtagcacc tattattaat
    13921 acattggaat ctttattaaa tccatccatt tcaactaaaa gttggtttag tgtttggtct
    13981 ttttcgttgt tactttcaag atgtctcttt gctcctacag catctatttc gtctataaat
    14041 attatacttg gagcttcttt tctagctttt tcaaatagag ttctaactct ttttgctccc
    14101 acacctacat atttttcaac gaactctgaa ccagtaacat tgaaaaatga tgagtttgtt
    14161 tcaccagcta cagcagatgc aagtagggtt ttacctgttc ctggaggacc ataaaataat
    14221 actcctttag gtatttttgc acccattttt tgatattttt gtggtgactt cataaaatcg
    14281 actatttcaa atagttcttc ttttacttca tctaatccag caacatctct aaatgtagtc
    14341 tttggttttg tagaaagtga atcatctgtt tgattatctc tttccatttt tgtctgtgca
    14401 aagacaggag ctggattgtt gattttctta aaaaagttgt ttagcatttt catattcaca
    14461 cctcaggtaa ttaattattg ttaatcaatt ttatattttc catatttact attttttatt
    14521 atttattttt catggaaaaa atatacatgt tatctaaata aaaataaatt tgtaagatgt
    14581 atgaaaaaat gaatttatgt atatagagat ttctacttat gtattgaata aagtattaca
    14641 aattataaat tatgtattga ttatatattg agtaaagtat tataaagcat gtattgatta
    14701 agtattgaat aaaatattac aaatttagtt gaaatgaaaa tgataaaaaa tcttgtacta
    14761 tattttacaa atcatataaa tagagaaatt gttgtagcac aaagtagtag gtagtatatt
    14821 agaatataat ataggatttg ttgtgtagta tagtagcata ttagaatata atataggatt
    14881 tgttatgtag tatagtagta tattagaata caatatagaa tttgttgggt agtatagtgt
    14941 tatattagaa tacaatatag gatttgttat gtagaatata tagagtcatg tagaatataa
    15001 atatataaaa ggattttggg tataaattta aaaattaata gcaaaatgag tagtatagac
    15061 atataattag tagtaggaag taattaaatt tttcctaaac aaaaaaaata gttgcaaata
    15121 atttgattaa gtgatatagt agataaggta agaataaaac aaagaagaag tccgcttctc
    15181 accttacgcc ggaggttagt aaggtaaata taagttaaag cttaatttta atttaagttt
    15241 gtttaaattt ggtaacttat attgcggatg attacgtcat ccgcttttta ttttataaaa
    15301 attttggagg tgtcctacaa ttagcaaaga attagcaatc aatgaacaaa taaaagataa
    15361 ggaaataaga gtcctttcac caacaggtga acaacttgga gtaatgccta ctaaagaagc
    15421 tcaagcaatg gctaatagca aaaacttaga tttggttcaa atctcgccga atgcaaatcc
    15481 accagtatgt aagataatgg attatggaaa gtttagatat gagcaagcga gaaaagagaa
    15541 agaagctaag aaaaaacaaa aaactatagt tgtaaaagaa gtaagactta gaccaggtat
    15601 tgaacaaaat gatttaaata cgaaagctaa taatgctata aagttcctta aaaaagggga
    15661 taaagtcaaa gttgaactta gatttagagg aagagaatta ggacataaag acataggtaa
    15721 agaagttatg cttaagtttt tagatataat aaaagagttt ggagaaccaa caaaagcccc
    15781 tgcatttgag ggtaataata tggttgtaat tatagatcca aaaaaataga tgattaactg
    15841 agaggaggaa tttgtcatgc ctaaaatgaa aactcataga ggtgcagcaa agagattaaa
    15901 gaaaacagga actggaaagt taaagagagc taaagctttt aaaaaacata tattaactaa
    15961 aaaatctgca aaaactaaaa tgaacttaag aaaatcaact ttagtaagtg atggagatgc
    16021 taagagaata gcacaattat taccatacta agatacagat tgtaaataat aactatagaa
    16081 gagggatata aaaggaggtc ataacgatgg caagagttaa aaaagctatg aacgctcgta
    16141 aaaagcataa gaaaatatta aaacttgcaa aaggattcag aggatctaga agcaaattat
    16201 atagaccagc aaatacattc gtaatgaaag cattaaaaaa tgcttatata ggaagaaagt
    16261 taaagaagag agacttcaga aaactttgga tacaaagaat aaatgcagct gctagaatga
    16321 atggaatatc ttattcaaga ttaatgaatg gattaaaatt atctggtatt gaagttaaca
    16381 gaaaaatgtt atctgaaatg gctatacaag acccagaagg atttgcaaaa ttagcagaag
    16441 ttgctaaagc aaaattagct tagtattgaa tcatgagatg taaagtcttt gagttatata
    16501 aataattcaa ggactttttt attttttgaa aaatacttat tagtgtcatg tacaaccaat
    16561 tttataatga taaataaaat aagcaataca atagaatttt atgagattta ttataagaat
    16621 tgttacaatt atttatgata gctataaaaa gtcatagtaa aaatgatatt gatgtatgtt
    16681 gatatatgta taaagctttc aatcaatctt gaattaatat tatcaacatg ataatattat
    16741 cttattaata atataaataa gggggagata atatgaatga aaaactaatg gattgttttg
    16801 taaacccaat taaatgcaag ttattgattg aaattttttc aaataatcga actacagcta
    16861 aacaattagg agaaaaattt caagatatat caaaggcaac actttatcgt taccttaata
    16921 aaatgttgaa agatgatatt ataaaagtag ttgaagaaaa taaaataagg ggaactgttg
    16981 aaaaagtata tgctatgaag ttagatatag ctgatgatgt gaacaaaatt atagatgaga
    17041 actctggaga agaatatgct caactgttta ctcaatatat gatgggattt ttaagagaat
    17101 tttatgaata cgctgaaaga aaggaaaagg atatcctaaa agatggttca ggattttctg
    17161 tctgtccagt atatgctagt attgatgaga tagttgaagt gagtaaaaaa attgctagta
    17221 tactagaacc tctaagaaat aactcgcacg aagaaggcag aagaatgcat tctataggag
    17281 tgataatcac tccacctaaa gaggatgaag ggaaataaat ctgatttaca tgaggtagag
    17341 ccaatttaca cggaaaatcg ttttatgatt tacatatgta tccagagcaa agtatctctg
    17401 cttggattgt acttcattgt atcatttcat ctatctaatg acttggagtg gtacaatgaa
    17461 gttttttaat ttttcatatc aatgcctaaa gaaatgaact ttagaccaca tatgcaatta
    17521 ggttacatta tacaattaga ccagatatac aaaataaaaa tcagtatttt tatagcagat
    17581 aaattgactg ttattcttct taaaaatcat ctattagtta ttgttagcat attgaaagaa
    17641 attataggaa tctattgaat aaatgaatat tgcccataat catataaact gctatagttt
    17701 aaaataaagc aggacgttaa attttatagt aatctaaaaa tttaagaggg ggattttatg
    17761 aaaataa
//
LOCUS       DAGQVA010000083        17700 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.083, whole genome shotgun sequence.
ACCESSION   DAGQVA010000083 DAGQVA010000000
VERSION     DAGQVA010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.083"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..257)
                     /locus_tag="MIV85_003098"
     CDS             complement(<1..257)
                     /locus_tag="MIV85_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBY2962422.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFY"
     gene            484..1185
                     /locus_tag="MIV85_003099"
     CDS             484..1185
                     /locus_tag="MIV85_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962423.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            1267..1875
                     /locus_tag="MIV85_003100"
     CDS             1267..1875
                     /locus_tag="MIV85_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBY2962424.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            2199..2663
                     /locus_tag="MIV85_003101"
     CDS             2199..2663
                     /locus_tag="MIV85_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HBY2962425.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            3300..4316
                     /gene="gap"
                     /locus_tag="MIV85_003102"
     CDS             3300..4316
                     /gene="gap"
                     /locus_tag="MIV85_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBY2962426.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            4711..5880
                     /locus_tag="MIV85_003103"
     CDS             4711..5880
                     /locus_tag="MIV85_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962427.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            6260..10513
                     /locus_tag="MIV85_003104"
     CDS             6260..10513
                     /locus_tag="MIV85_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBY2962428.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDIPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            10662..11156
                     /locus_tag="MIV85_003105"
     CDS             10662..11156
                     /locus_tag="MIV85_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBY2962429.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            11272..11649
                     /locus_tag="MIV85_003106"
     CDS             11272..11649
                     /locus_tag="MIV85_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBY2962430.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            11855..12295
                     /locus_tag="MIV85_003107"
     CDS             11855..12295
                     /locus_tag="MIV85_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBY2962431.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            12954..14261
                     /locus_tag="MIV85_003108"
     CDS             12954..14261
                     /locus_tag="MIV85_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962432.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYYNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    14347..14609
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            14735..15538
                     /locus_tag="MIV85_003109"
     CDS             14735..15538
                     /locus_tag="MIV85_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2962433.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            15576..16187
                     /locus_tag="MIV85_003110"
     CDS             15576..16187
                     /locus_tag="MIV85_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBY2962434.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            16219..16890
                     /locus_tag="MIV85_003111"
     CDS             16219..16890
                     /locus_tag="MIV85_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBY2962435.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            17188..17550
                     /locus_tag="MIV85_003112"
     CDS             17188..17550
                     /locus_tag="MIV85_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBY2962436.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
BASE COUNT         7224 a         1683 c         3090 g         5703 t
ORIGIN      
        1 atataaaaat atactaataa aaattgtaaa aatagtataa atggtatacc aaatgtaaat
       61 ttaatgtgtt tagttttatg tctaaaagaa tacattccaa ttatagaacc tatactacct
      121 ccaattactg ctatagacat aagagtagct tcttttattc tccattcgtt tctaattgct
      181 cttttcttat ctatgtacat tgaaaagaaa gcaatagaat taatcactat aaaatatatt
      241 agaataaaat ttttcacagt cttgcctcca taaaaatata ttatacatta taaaacaaga
      301 tatttgtttt ggaaagttaa atttgtaatt agtacatata aaatatttga taagaacaaa
      361 tataatatta attggaaaat ttaaaaaaat taaacaatta gcaaataggg ggtatattta
      421 taagacacaa agtgataaaa tctatttaga aaataatgta aaataacagg aggataaagc
      481 aaaatgaaat ttatagtaga aaaagaagtt tttgataaat tagaaaatgt atgctttggt
      541 gtagtagttg caaaaggaat agataatact aaagaaatag aaagaataag caacctttta
      601 gatataagta tagatagagt agaagattac ttcaaagata aaaaagtaaa ggaatcagaa
      661 gaaattatac catatagaga ggcatttaga agtctaggca tgaacccaaa taaatttatg
      721 agttcgatag aagcaatgac aacaagggtt gctaagaata agaaacttcc tcatataaat
      781 cctattgtag atttaggaaa ctctatttct ttaaaatatt tacttccaat gggtgctcat
      841 gatatggatt ttagaaatga tgatgtatat gttagatttt ctaaaaaagg ggataaattt
      901 gtaccatttg gagaaactga tgttgaatta atggaagaag gagaattaat ttattcagtt
      961 ggagacatgg taaaaactag aagatggata tggagacaag gagaagaagg aaaaattact
     1021 aatagctcaa aaaatatatt ttttcctata gatggtttta ctgatgctaa tttagataag
     1081 gtaatgagtg caagagaaga attagcaaaa ttgttaaagg aaatatttaa ttgtgaaatt
     1141 aaagtaggtt ttgtagataa agataatcct gaaatggaaa tataataagt tgttgaatac
     1201 ttgttaagat attatattta cttaatgatg ttaaaaaggt attaaaaaag aaaggtcgta
     1261 gtaaatttga aaaaaactat aataaagaat gtaaatccaa tgattgaaaa taagtttata
     1321 ggactttttg aaatagagta taaaaacaaa ttagatgaag ataaggtttg gatggtagca
     1381 tcaagaaaaa gtagtgagca attaaaaaat atttatttga agaatgaaga agatagtgta
     1441 gatgcagttg taatagttgg gcttcataaa agtagtaaaa aattaatttt aataagacaa
     1501 tttagagtac ctattaatgg atatatatac gagttaccag caggtcttgt tgatgaagga
     1561 gagtctatag atatttccgt tgaaagagaa cttagagaag aaacaggact tactctttta
     1621 gaaattaaaa aaaataaaag tattgataaa gtttatttat ctcctggaat gagtgatgaa
     1681 tctgttgcct ttgtttattg tatatgtgat ggtgatataa cagatgaatt tttagaacca
     1741 gatgaagaga ttgaagcgct tttaatttcg caagaagatg caaaagagat tttacaaagt
     1801 aatcataaga tagacacaaa agcatttttg attttacaaa tgtttgtgag tttaggagct
     1861 aaattatttg aatagatata tagaaaagag gttatataga agagtaaaat aataaagttt
     1921 attttacttg tgtaaattat aatctctttt tttatacaat aaagtataat tttgtgtatt
     1981 tttaaataag tgatttgact cttaaatttt cataatatgt tataaaccaa tttaagatac
     2041 tacaataatt aaaattccaa aattatttaa catatttgca attaaaatga gaaaatgtaa
     2101 aggctgaatg attgaaaaat ttgatgtaaa atagtagctt agtttaatac tatagtttgt
     2161 agggttaaaa attagaaatt gtaagggaga taaattctat gaaaaaatta gttattattt
     2221 taattagtat cattagtatg gttagcttga cagcttgtaa aaaaagcaat gaaagtaaat
     2281 ataataattt aaacaacaaa gaatccggac aaacaaccat tgaaatggac ttagataaaa
     2341 attatgatac ttcagaccca tttgttaatg cacgtttgtt ttgtgtgtct aatgatatag
     2401 atgttttaga cacagagatt tcttttaaaa tggatggaga tagtggtatt gtggaaataa
     2461 aggacaataa aacagatgaa actttatgga gtaatacatg gcatggaagc gttgataatg
     2521 atacattcac aatttctctt tctaatatac aaaaagagaa agagtatgct atatgcttta
     2581 ctggaattaa aataaatcat gcagttgtaa aggttacttt tgaaagcaat ttagttaagg
     2641 agaaagaaaa accctcaaaa taaattccag cttttctata acttgatatt cagtacataa
     2701 aagcagttga tatttatgat tgactgcttt ttcttatcaa aaaggatagg ttgtgcattt
     2761 ttacttgaaa tagtttatgc acatcaaaag ttggtgagca tgatattgga aatggtaagc
     2821 atgaaatctt gataatacaa ggaaataaat ttaagttttc aattaagtat atttccataa
     2881 tttagttaac aataagctaa ttattattta tattttgata tataaataat aattgtagca
     2941 aattttaaaa aatcatatat tttttgaact aaataaaaat ttatttttat tattttaaat
     3001 tagaggagat tcttgaagat atattatttt taaaaataag tatagtttaa aaattcaaaa
     3061 aaaagatggc aaaatatgtc ccaagggaca ttgagtaaaa taaatgattt cagcttattt
     3121 acactaaaaa gtacatacta aatgaggggt aaaataaaga aaaatgatat actaattgtc
     3181 ttttgataat aaaaaaacat ggaatttgat tatttaatca agaaaaagta ttgaacaaat
     3241 gatttattta gtgtacaata atcatgtaaa aacatagtaa tggagggaga catttcataa
     3301 tgaaaattaa ggtaggaatg aacggatttg gaagaatagg aagagctgta ttaagaatag
     3361 ctcaagaaga attaggagat aatatagaaa ttgtagccat aaatgcaaga gcaacaacag
     3421 aatctttggc acatttattt acatatgatt catgctatgg aacttttaga ggtgaagtag
     3481 aggcaaagga tgaagacact ctagtagtaa actctaaaga gataaaaata ttaagatata
     3541 atgacccaga agaattacct tggaaagaat tgggggttga tatagtaata gaatcaacag
     3601 gattatttac acaaagagaa aaggcagaaa aacatattaa agcaggagca aaaaaagtaa
     3661 ttataacagc tccaggaaaa aatgaagata taactatagt tatcggagtt aatgagaaag
     3721 aatatgataa tgaaaagcac aatataattt caaatgcatc ttgtactaca aattgtctag
     3781 ctccttttgc taaagtattg gacgaaaaat ttggtatagt aaaagggtta atgactacag
     3841 tacattcata tactaacgat caaagaatat tagataaaag ccataaagat ttgagaagag
     3901 caagagcagc ggctgaatct ataataccta ccactacagg agcagcaaaa gctgtgtcaa
     3961 gagtactacc acaattagaa ggaaaattaa atggtttttc acttagagta ccaacaccaa
     4021 cagtttcact tgttgattta gtgtgcgaac ttaaagaaaa cgttacatct gagcaagtta
     4081 actctgtgtt aaaagatgct gctgaaggag aattaaaagg tgttttagga tattgtgaca
     4141 agccacttgt ttctatagat tataaaggag attcaagatc atctattata gacgctctat
     4201 ccacaatggt tatagaagac aatatggtta aggtagtttc ttggtatgat aatgaatggg
     4261 gatattcttc aagaactgtt gacttagtaa aatatgtagc tgaaaaatta aaataatata
     4321 tatttcttaa agcaaatttt aaaaaaattt tttaaaaaaa ttatataaaa ctaaaaaaaa
     4381 agattatgaa aaatattgaa ggaaaaattt tttcataatc ttttttcttt catgcaaaaa
     4441 gatacaagtt acaacttata tttgcatatt aggtcgttag agaagtatat atatatttag
     4501 taaggaatca tactttttat aaaatgaaag ataagatgtc gaaaacttgc ataaatctga
     4561 aaaattttta ttattaaaat actgatttcc attttaaaaa tgataaaaaa atgacaaata
     4621 aagttgcaaa tagtaatact tataagtata attaaaaaag agaaaaggtt ttgttaaact
     4681 ttataacaaa aaaagaaggg atgattcaaa atggagaagt taacagacag gagacaggtt
     4741 aaggcagtaa gcatggaaac cttcattttc ctaatattac tagtagttgg ttttgggtat
     4801 gttggtagta ttatgggagc aggaatgatg ttcaaagtaa taatgagtac agcacatgct
     4861 ttactattgg agacagtttt cttaattatg gctatggcag ttcttgcagg cgcattaagc
     4921 gcactacttt cagagtttgg agtaatagcg ttaattaata aaattttcgc tgtatttatg
     4981 aagcctttat atggactacc tggtgctagt atagcaggag ctataacaac ttatttatca
     5041 gataatccag ctattatacc ttttgctaaa gataaaacat tcacacagta ttttaaacaa
     5101 taccaagttc cagcattatg taacttagga acagcctttg gtatgggact tatcttaaca
     5161 acatttatga tttctcaagg tacagaatat gtacttccag cattaattgg taatttaggt
     5221 gcaattatag gtagtgtcat aagtgttaga ataatgttga catttactaa gaagttttat
     5281 aaatacaatc cggaagaaga taaagcaaca ggaacattag agaaaaagga tgaatttaga
     5341 gaaatcagag aaggaaatgt atttcaaaga gctttagatg caattcttga aggtggtaaa
     5401 atgggggtag atatgggaat ggctataatt cctggagtcc tagtagtatg tacattggtg
     5461 atgttattaa cttttggacc atctacagat cctgttacag gtcaagaagt ttatacagga
     5521 gctgcatatg aaggaataaa attacttcca gttattggag ataaacttgg atttatatta
     5581 gaaccattat ttggatttac atcaccagag gcaatagcat tccctataac ttcattggga
     5641 gctgttggcg cagcaatgtc tctagttcca gagtttataa agtcaggagc tataactcct
     5701 aatgatatag cagtatttac agctatgggt atgtgttgga gtggatattt aagtacacat
     5761 attggtatga tggatgcatt aaatgctaga cagttggcag gtaaagctat tctttctcat
     5821 acaataggtg gtttatgtgc aggagcagct gctcacttta tatttacact cgtaggataa
     5881 atgtaatcag ctaagataaa aaataatata caaaaaatgg ttgttgatat gtaataagaa
     5941 tttacatatc aacaaccatt tttttctgac taaagataat ttataataca taaacattaa
     6001 gtggatatta gagttaagtt atatttatgt aaaaagtaac aaaaatctgt agaaatttat
     6061 gacaaaattt agtacactaa ctatatgttc ttatttaaaa tttaaggtta gaattaggaa
     6121 ttacctagta gagtaagctt tgattaataa aagaatcata aaataaaaat attagtcata
     6181 aagattataa ataacttact taaaataaag ccatagaact tacaaaaatt aaaaaagcat
     6241 ataaatatgg aggggtacaa tggatgaatt atttcatata ggaattgatg taggttctac
     6301 aacggtgaag gttgtggtac ttaataatag taataatata gttcataaag aatatagaag
     6361 acattattct gatgtaaaaa aatcagttaa agaagtacta aatggtatat atgaaaaatt
     6421 gggagatata aatactacca ttataataac tggttcaggt ggaattggaa tatcaaaaaa
     6481 attaggtgta aaatttgttc aggaagttat atctagtaca aaatcaatag agtattttca
     6541 tcctgaaact gatgttgtca tagaacttgg gggtgaagat gcaaagataa catatctaag
     6601 tggaggaata gaccaaagaa tgaatggaat atgtgcaggt ggcactggag cattcataga
     6661 ccagatggca tcacttttaa agacagatgc cagtggatta aatgaacttg ctaaagggta
     6721 taatgttata tatcccatag cttcaagatg tggtgttttt gctaaaacag atattcaacc
     6781 tcttataaat gatggagcca atcagactga tatagcaatg agtattttca atgcagttgt
     6841 cgtacaaact gtgagtgtcc tttcttgtgg aagaaaaata gaaggaaatg ttgcgttttt
     6901 gggtggtcca ttgtactttt tatctgaact tagagaagca tttaaaagag tattagattt
     6961 aaaagatgaa aacataatct tcccagaaaa tgcacaactt tatattgcta ttggagcagg
     7021 attattatca gtagatgaag ataatataca actaaaatct ctaatagaaa aattggatag
     7081 tataaagaat attgaagatg gagaagtaaa tttattagaa cctttattta aagataaaaa
     7141 tgagtatgaa gaattttcaa gaagacatga aaaagaaaaa ataaattatg tggacataaa
     7201 ttcaataaaa agcaattgtt atttaggaat tgatgcaggc tcaactacaa ctaaagcagc
     7261 acttattgat gaggatggaa gacttgtata ttcttattat aatagcaatg aaggaaatcc
     7321 attaaaaaca accattaaag ttataaatga agtatatgat atattaccaa aaaatattaa
     7381 aatattgagt tcaactgtaa ctggatatgg agaaggtctt attaaaaaag ctcttaaaat
     7441 cgataatgga gagatagaga ctatagcaca ttacaaagct gctaaatttt tcaacaaaga
     7501 tgtagatttt atacttgata ttggtggtca agatatgaag tgcctaaaaa taaaagatgg
     7561 agtaattgat aatataatat taaatgaggc ttgttcatca ggttgtggct catttttaga
     7621 gacatttgca agttctttat ctatgacaat agaagaattt gcgcatgaag gtatttattc
     7681 tcaaaatcct gtagatttag gttcaagatg tactgtattt atgaattcta gagtaaaaca
     7741 agctcaaaaa gaaggtgcaa gtgttggaga tatatcagca gggctatctt attcagtaat
     7801 aaaaaatgct ttatttaaag taataaagat tagagattta aatgagattg gtaataatat
     7861 tgttgtacaa ggtggaacct tttataatga tttggtgctt agaagctttg aaaaactaat
     7921 tggaaaaaat gtaattagac ctaatatttc aggaattatg ggagcttttg gttcagcact
     7981 tatagctaaa gaaaaatatg aaagtggata caaaacatcc ttgttatcta aggaagagtt
     8041 gaataatatc aagctagaag caagtgtaac tagatgtaaa ggttgttcaa atcattgtct
     8101 tcttacaata aataaatttt ctgataatga aatttttatt tcaggtaata gatgtgagaa
     8161 aggtgaagct atttatggtg ataaaaaaat aggattagaa aagaaaaaac caataaattt
     8221 atttaagtac aaatacaata gaatttttag atacaaacca ttggaaaaag aagaagcaaa
     8281 aaatggggaa atagggatac caagagtatt aaatatgtat gaagattatc cattttggtt
     8341 tacttttttc aatgctatgg gctttagagt tgtactttca gataggtcat caaaacagtt
     8401 atatgaaact ggtataacta gtattgcatc tgaaacagtt tgttatccag gaaaattagt
     8461 tcatggacat atagaaaatt taattgcaaa aggtataaaa aatatatttt atccaagtgt
     8521 aacaaatgaa aataaagagg attcaaatgc agataattat tataattgtc ctgttgtaat
     8581 atcatattct gaagtaataa aaaacaatgt agagaatata agaaataaga acataaatta
     8641 tataaatcca tttataagtc taaatgacaa ggaaaaattg aagaaaagac tctatgatga
     8701 attatcaaga catttttctg atataaaaat aactaaagaa gaagttaatc atgcagttga
     8761 taaagctact gatgaacaga atttatttaa aatggagata caagcagcag gtgaaagagc
     8821 acttaaagaa ataaaagaaa gaaatatgaa ggggattgtg ttatgtggaa gaccatatca
     8881 tatagaccca gaaataaatc atggaatgcc agagcttata aattcattag atatggcagt
     8941 gcttactgaa gactctatat gtcatttagc caatgtacaa agaccactta gagttgtaga
     9001 ccaatgggta tatcattcaa gattgtataa agcagctagt tttgtaagag ataaaaacta
     9061 tttggaactt gttcaactta attcatttgg ctgtggatta gatgcagtaa ctacagacca
     9121 ggttcaagaa atacttaatg aaaaatcgaa gatatatact attataaaga ttgacgaagg
     9181 caacaattta ggagcagcta agataaggat gaggtcctta aaagcagcta tgtttgagag
     9241 agaaagcaaa aatatagatg taaaaaatat aaaggtaaac aggatacagt atgctaaaaa
     9301 taatcagata acgaacaaac atactatatt agcaccacaa atgtctccaa tacatttcca
     9361 attccttgaa aaagctgtta acttaagtgg ttataatata gaaattctaa aagatactga
     9421 tagtagtgta attgaagaag ggttaagata tgtaaataat gatgcatgtt atccagctat
     9481 aatagttgta ggtcagctaa taacagcatt aaaatctggc aaatatgatt taaataacac
     9541 ttctgttact ataactcaga ctggtggagg ttgtagagct acaaattata ttggattctt
     9601 aagaaaggct atatacgatg ctggatttaa agatattcct gtcattgcac ttagtgtaaa
     9661 tggaatagaa gatagtggta taatggataa tatatcacta aaattaatca atagactctt
     9721 tatgtctgtt gtttatggtg atttgctgat gaaagtacta tatagagtaa gaccatatga
     9781 aaaagttact ggaagtgcaa atgctctata tgaaaaatgg gttgatatat gcaaatcttc
     9841 tcttgttaaa gcaaaaattt ctgtatttac tagaaatata aaagatatag taaaagaatt
     9901 tgataattta gagatactag atatcaaaaa accaaaagta ggtttggttg gagaaatatt
     9961 ggtgaaattc catccaattg caaataataa tttagtagat atattagagc gagaaggtgc
    10021 tgaagcagtc gtgccagacc ttacaaattt cttcttaagt tgtgccttta atactatata
    10081 caaacacact catttagaag gaagtagaaa gagtagaatg ataggagaag catttatata
    10141 cataactgga atatatcaaa gagtatataa aaaagcactt gataagagtg agagatttta
    10201 tgctccagcc aatataaaaa atgttgctaa aagtacagaa ccagtagtgt cattaggtaa
    10261 tcaaactgga gaaggttggc ttttaacagg tgagatggtt gaattattaa atgaaggtgt
    10321 agaaaacatt atttgtatgc aaccttttgg atgtttacct aatcacataa ttggtaaggg
    10381 ttctataaaa gaattaaaga ggttgtataa aaatgcaaat ataataccta ttgattatga
    10441 cccttctgca agtgaggtaa atcaacttaa caggataaaa cttatgcttt ctaaggcttt
    10501 taaaaatata taagatttat attttgatat gttaaaagtt aatgaattta aaaatatact
    10561 ctatattaag tatctataaa aaagagttat cctatttttt agggtaactc tttattagtt
    10621 aaaaaattat atgtatactg atattaaagg ggggaagtaa tatgagttta gtatatgatg
    10681 tttataaatc aaaattagga aatttgtaca tattaagtga agatggtttt atagttagta
    10741 tatacatagg agatgaaaaa tttaataatt taaaaaatga atgtattaaa aaaggaattg
    10801 atataaagag aagtaaggaa gatttaaagg aagcaataag ccagatagat gattacttta
    10861 atggaaaaag aaaagtcttt aatttaaata ttcgtattga agggactgaa tttcaaaaat
    10921 cagtttatag ggaaatgtta aaaatacctt atggagaaac attgtgttat tcagatatag
    10981 caagaaatat aaacaatcca aaatcagtaa gagcaatagg acaagcaagt aaaagtaata
    11041 aaattccaat aataatacct tgtcatagag tagttggcaa aaaagatatt ggtggatata
    11101 tggggaatca ttctgatttg aaagagatac tattaaattt agaaagacag agttaactta
    11161 gaaagaaatg tttttattgt taatatttga tataataata gtaaaaagaa gtatttttta
    11221 caaaaacaat gaagaattta ttttaattta taaaaatgag ggggaatttt aatgtgtgat
    11281 aaagttatag catcaaaata tcatgagaag ggatttaatt gtgcagaatc agttataaaa
    11341 gcatataatg aggaatttaa tacagatata ccagtttgtt taggaagtgg actgggttca
    11401 gggtgtgggg ttgctagttt atgtggtgca gtaaatgcat caaatataat aattggatat
    11461 gtaaaaggca gaaaccacga agatgaaagt actaaagcta aagtatatgc taaagattta
    11521 actacaacag taagaaaaga gtatggttca gagttatgta tagacctaaa aaaagattta
    11581 gttgcttgta gagaaataat ggatttcgca tatgatagtc taaaggaaac tttaaaaaaa
    11641 gaattataag aaaataagct atcaagtata aattatttga tagcttattt ttatagtcga
    11701 tactaaataa atcaaatata ttttagaatt attatttgta aataaacagc aaataatttt
    11761 aggattttta tttaatatag tttttattta tatttatttt tgaatatgtt atactttgtt
    11821 taaataaata tttgtaatga gggagatgag aagattgaag aatctcaatt tacttattaa
    11881 taaattatat tcaaaaaatc ataatgaagc atataaaact tttttattct tagaaaatga
    11941 aagtttaaaa tcaaatatta catattgttt ttttgactca ttcctagaaa tgattgataa
    12001 cgaaaactca tatattcgaa caaggggatt gttattaatc tctgcaaatg ctcagtggga
    12061 tattgataat aaaattgaaa taaatataga tagtatacta agtcatatcg tagataaaaa
    12121 accttctgta tcaagaatgt ttattaaatc catacctaat attacaaagt ataaagaaaa
    12181 tcttattaat cgcataaaaa tggaattaag taatgcagat ataagtattt ataataataa
    12241 tatgaaacca ttagtagaaa aggatataaa cgatacatta tctaatatta gttaaatatt
    12301 aatatagaaa ttgaatatta tctagttaca attatttata actaagataa taaaacaaca
    12361 atggtgctaa tttatatgta taaattaatt atgaaaaatt tatataagta aaatatatta
    12421 acataaaggt aaaattttgt atactaaaag ggaatattta cagtttaatg gcagttttaa
    12481 aataataaat taaagctgtc atttttattt aaaaattttt agaaaaagta caatagtgtt
    12541 aatgtgtgaa ttagataagg tgtatataat agtttagatg atatgatata aaatatgttg
    12601 taaattaaat gttttctttg acaatatata cacaaggatg ataatatcta tatgaataaa
    12661 agatagtgtg taatttgata atatgtaatt ataacattat gatataatta caataaagta
    12721 tgtaataatc tgtagaaatt tcaagctagt tatctaagtt ttcggataac taaatctaaa
    12781 cggaatacat aatgtattaa ataaatgatg atactaaaat gatactattt ttatagaaat
    12841 ttattgaggt atataattaa tgaaaataat atattaaatt atataaatta aattatataa
    12901 attaaattat ataatatatt gagttttaca taaaagcaaa ggtgggaata aaaatgaaag
    12961 aaattgctga tgctataaca tcagagtatt taagctatgg tatcaatgaa gatattagta
    13021 tctatgaagg tagattttgc atatatttag ataaaaaata tagatgtaat gggaaaattt
    13081 attataaaat gacacctcca atatctataa gttttaaagc agacataggt tgtgttgaag
    13141 agatagacaa tgaagatgac aatttagctt tagattatga taatgctatt cttgaagttc
    13201 atggatataa aattatttct ataacaataa atactttaag tgaatttagt gtagaaggtt
    13261 atatcaatga tgactgcata aaatctaaga actcctatgt tgaatatgta gattttaata
    13321 taataaactt agataaaata cctggaaaac tcattaaata caatgataag gtatacgcag
    13381 gtagaattga atttgatata aatgattatg ttgtaactat agacaagcga tatgattata
    13441 gaaaagaatt aaaatcagaa ttaaagtcta aatctggagc aataataact catataggta
    13501 ggattagaag aaaagatggt agaattttta gaacaaataa tacaataaat cttttagata
    13561 ggatatcaac agctttgagt tttatgtgtg gaagatatgt agggttttgt ttggccaaag
    13621 ggtatagaag tggtaatgaa gtttatagaa tatggaatga aaatcaaata tctcctttta
    13681 gatatgtacc aacatggtca gatacacttt caaattatta taatatggaa aaatatataa
    13741 gccttatgtg taaaaagcta gaagattttt attatggttc tgctataaag agtgttgttg
    13801 attggtacat agaatctctt ggaagtgcta ccatggaaaa caatataata tctgtacaaa
    13861 ttgcacttga aactttgtca tatgtaattc tagtggaaca aaataagata cttacagatg
    13921 aagtatttga ctgtaatttg gcatctaaaa atataagact cttacttgat acatgtaaga
    13981 taccatatgg taaacatgaa ttaaatatat ttgataatat aataaaaaat aaatttgatg
    14041 atggagtgga tttagttatt tatttaagaa atagcatagt tcatccaagt agaaagactc
    14101 atagagctgt gttagaggtt gaagatattt ggaatataat ttcaatagga acgagatata
    14161 ttgaacttgt tttactcttt attttaggtt atagaggaga atattcaaac agattagtag
    14221 aaagatgtta tggtgaagtg gaagttgtac cttggaacta gatttttata tttattttaa
    14281 aatatatatt gacatatatt gccttatgct ataaaatcaa tatcataata ataattcaga
    14341 ataacattaa atgctaagaa aagaaatagt aaaagtagtt aatcttaaac agagagtttc
    14401 cgattggtga gaggagcaat agattttact ttgaacacat ctttgagcag gactctgaaa
    14461 gagtagaaat actttattag gagatttccg gaatccttgc acccgttata gtgctagagt
    14521 ataataattt tattgtactt aaagaggtta gtgtcgtgag gcattaatga acagaggtgg
    14581 aaccacgaga gttaactccc gtcctctagc agaagctaga ggcgggagtt ttttaatata
    14641 attttttaag cgcgcagaga attatattgc aatagataca ctttttaaaa aataatcaaa
    14701 atattttaaa aattaaaagg cgagggagaa tattatgaaa aatatattaa aaaaagtagg
    14761 aatatttaca attatgttag gtttattagg tggagttgta ggttgttcaa aaccagataa
    14821 tgaaaaagat aaggatgctt caaaggaatc taaaaaagaa gtagttgtag ggtttgataa
    14881 tacgtttgta ccaatgggat ttttagatga aaagggagat acagtaggat ttgacgtaga
    14941 cttagctaaa gaaacattta aaagacttgg aatggaagtt aagtttcagc ctatagattg
    15001 gtcaatgaaa gaaactgaat taaatgattc aaaaactgta gatgtattat ggaatggata
    15061 ttctataaca gacgaaagaa agaaaatagt atcatataca gaaccatatt tacaaaataa
    15121 gcagataata gttactctaa gtgactcaaa aataaattca aaagctgatt taaaagataa
    15181 agaagttgga acacaacaag gttcaacagc acttgatgca gtggaaaagg ataaagattt
    15241 tatgaatagc ttaaaaggtg gagcaccagt tctttatgat acttatgata aagcacttag
    15301 agatttagag ataggtagaa ctagtgcagt tgttggtgat gaagttttaa ttagatacta
    15361 tatgggacaa aagggtgaag acaaatacaa ggtattaaaa gacgattttg gattagaaga
    15421 ttatgttgta gcaacttcta aagaaaatcc agaactttgt gagaaaataa atgaaacatt
    15481 aaaagaaatg aaaaaagatg gaacttttga caagatttat gataagtggt ttaaatagaa
    15541 gataagttag ctgttaagaa gggggcacta aaggcatgtt acaaggttta gagatagtta
    15601 tagcaatgtt ttgtataaca ttgatagtat caattccatt ggggattgga gttgcatttt
    15661 taagattatc aaagaataaa ttagtaagtg gtattacaca atgttatata ttgataatga
    15721 gaggtacacc tttacttttg caaatgatag tcatatttta cggattacct cttttaggaa
    15781 ttgtatttga cagatttaca gctggagtag tagctttctt cttaaattat gcagcatatt
    15841 ttgcagaaat atttagaggt ggaatacagt caatcgatag aggacaatat gaagcttcaa
    15901 aagtactagg atttgataag tttactatgt ataagagagt aatctttcca caagttttta
    15961 aaagaatact agcacctatt tcaaatgaag taatcacatt agtaaaagat acatctttag
    16021 tatatatatt aggattaaat gatattttaa gaatatctca aatagcaatg aacagggaag
    16081 caagtctgtt accattattt gaggcaggag cgatatatct tatatttgta gctatactta
    16141 ctaagggatt tgaattactt gaaaaaaaat attcttatta tagataaagt tacaatatta
    16201 taggaggagg ttttttatat gttgaaaatc aaaaacttaa ataaatcatt taaaaaaaat
    16261 agagtactta aagatatttc ttttgagtta gaagaaggtc agattggagt tttacttggt
    16321 aagtctggtg caggaaagac cacaatatta aggtgtataa atggtcttga agaatttgat
    16381 agtggagaga ttataataga taatgaggta ataaaaaata agagagatat ggcaaaaata
    16441 cgaggaaaaa taggtatggt ttttcaaaat ttcaacttat ttcctcatat gacagtcctt
    16501 gaaaatataa ttgaatcccc agttaatgtt tttaaagttc ctagaaaaga ggctgaagag
    16561 agggctagag aacttttaag attagttgat ttagaagata aattaaattc ttatccattt
    16621 gaattgtcag gaggacagca acagagagtt gctatagcta ggtcatgtgc attgatgcca
    16681 aaagtccttt gttttgatga acctacttct gcacttgata ttgatactat tcaaagagta
    16741 gtcaatataa tgaacagact taaagacaaa ggtatgacaa tattaataat tacacatgat
    16801 gttgtcttct caaataatgt tgcagataaa attataagta taaaagatgg tatagtagaa
    16861 aatgttcaaa taaaagaaaa aattgtttag agttttataa atataaacta gggtagaatt
    16921 ttataatata aataaagggc aagtaaaatc aaatatacta tgcccttttg ttatctcaaa
    16981 atttaatctt atattttatg tttaagttac attataattt ataataaaaa taaaaggact
    17041 atttaaatat ataatgtgaa taatgtttaa taatttgaaa tatgataatt ttttatgttg
    17101 aaagcttata atgattatga tataaattgg ttatagtata caatttatgg gtataacaat
    17161 aaaaaattag aaaggaattt ttataaaatg attaaattat atggatatac aaaatgctct
    17221 actgttaaaa aagctaaaaa ttggcttaag gaaaataatt tagaatttga agatatagat
    17281 atggttcaaa accctcctag taaagaggag ttaaaatcaa tttataagac tagtggatat
    17341 gatataaaga aattttttaa tacaagtggt atgaaatata gagaattggg tcttaaagat
    17401 attgtaaaaa ctgaatctga tgataaactt ttagaaatat tggtaagtga tggtatgctt
    17461 attaaaagac cattactttt ggatggtaaa aatgtattat tgggttttaa agaagatgta
    17521 tggaaaagta ctttgctaaa agaagattag gaagagatag gtgtgttgat taaaattatt
    17581 aattaataca cctataaatt tatgtattaa atctaatctt tataaatatt aattagcaaa
    17641 ttcaaatcaa aaaaattcat atcaacaaac atattacttc ttattacaaa ttatatcata
//
LOCUS       DAGQVA010000084        17255 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.084, whole genome shotgun sequence.
ACCESSION   DAGQVA010000084 DAGQVA010000000
VERSION     DAGQVA010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17255
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.084"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            429..724
                     /locus_tag="MIV85_003113"
                     /pseudo
     CDS             429..724
                     /locus_tag="MIV85_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1132..1821
                     /locus_tag="MIV85_003114"
     CDS             1132..1821
                     /locus_tag="MIV85_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962437.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIRYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            1821..2738
                     /locus_tag="MIV85_003115"
     CDS             1821..2738
                     /locus_tag="MIV85_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2962438.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLVEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRAIVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            2811..3737
                     /locus_tag="MIV85_003116"
     CDS             2811..3737
                     /locus_tag="MIV85_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962439.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVNPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            3734..4414
                     /locus_tag="MIV85_003117"
     CDS             3734..4414
                     /locus_tag="MIV85_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962440.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4512..4847
                     /locus_tag="MIV85_003118"
                     /pseudo
     CDS             4512..4847
                     /locus_tag="MIV85_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            5951..6601
                     /locus_tag="MIV85_003119"
     CDS             5951..6601
                     /locus_tag="MIV85_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2962441.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            6928..8994
                     /locus_tag="MIV85_003120"
     CDS             6928..8994
                     /locus_tag="MIV85_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBY2962442.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            9011..10966
                     /locus_tag="MIV85_003121"
     CDS             9011..10966
                     /locus_tag="MIV85_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBY2962443.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     NEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            10982..12172
                     /locus_tag="MIV85_003122"
     CDS             10982..12172
                     /locus_tag="MIV85_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBY2962444.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            13321..13695
                     /locus_tag="MIV85_003123"
     CDS             13321..13695
                     /locus_tag="MIV85_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2962445.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            13697..14554
                     /locus_tag="MIV85_003124"
     CDS             13697..14554
                     /locus_tag="MIV85_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962446.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            14557..15195
                     /locus_tag="MIV85_003125"
     CDS             14557..15195
                     /locus_tag="MIV85_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBY2962447.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            16201..16935
                     /locus_tag="MIV85_003126"
     CDS             16201..16935
                     /locus_tag="MIV85_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2962448.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
BASE COUNT         6554 a         1896 c         2887 g         5918 t
ORIGIN      
        1 atgaaaaacc aaacttatag attaaaaaat aaatgattta tagatgaaga actaaactta
       61 tagattaaaa aataaatgac ttatagatga aaaatcaagc tcatagatta aagaataaat
      121 aacttattag atgaaaaacc aagcttatag ataagaagtc catgcttata agccagaaaa
      181 tgaatagttt aatagattaa aaaatacata tttgtgaatt atagaatgaa taactccata
      241 aactagaaaa tttataataa tatctatatg aaaattagaa ttattttatc acaaaaaaat
      301 taagttaaat aaatatgaaa ttacttccaa atatacttcc aaaaacatgt aatcgcatat
      361 ataatataat tataaaaata ataaatattt ttatagtagt agttaattat taataaggag
      421 gggtcaaaat gcctagcatg attatggaag ttgtaggagt actatttata gctattggat
      481 taatcttgac attcattgaa ataaaaggaa atttcccttc tttttatggt tttggtcaaa
      541 attaaaatgc tgtaggtatt atagcagcag gaattgcttt aattttcttt agaaatggca
      601 tagatacata gattctatag ctacttatgg tgtattttta gcaatagaac ttgttgtaat
      661 agttgcatat ttcttaataa gaaaaaaatt tactaaagaa gataaacatt taagaactaa
      721 ttaactaaat tatctactat aaaattggaa aattaaaaac aaataaaagt ttgtttttaa
      781 ttatttaaaa tccaaatttg attattttta aagaaactat gttctgtata aaactagaat
      841 gtggtttctt ttttatgtat aaaatatttt ttagcaaaag ttaaaaggtg ttttataata
      901 taaaatagtt aattgtagat gttaataaaa gaaaattatg tatattttag ataaagataa
      961 gagagtatac tatattttaa ttcttttttc aataaagctt attgaaaaga actttaactt
     1021 agaagagtat caccaaattg cagatacaat atcataagca gttatttatt gacaaccctt
     1081 tttaataaat atatcatttg aagtatactg acgaaaagga gttgaataat aatggacatc
     1141 ttattggttg aagatgataa gaatattcga gaaatggtat acgattttct gattagtgag
     1201 aattactctg ttaaaactgc cattgatgga aatacagcta ttgaaatatt taaaaattat
     1261 tcatttgata ttattttact ggacttgatg ttaccaaagt ctagtggttt tgaagtatta
     1321 aaatatatac gaagtgtgag tgttgttcct gttattatta ctactgcgaa agatagtgac
     1381 acagataaaa tgctagggct taatctaggt gcagatgatt atattacaaa gcctttttca
     1441 atcgtagaat tgcttgcaag aattaaagct aatattagac gtgcaacagt gtatagcagt
     1501 tcaagaaact ctcaagatat ggttattcgg tataaggatt tgattataaa catatcaaaa
     1561 tatgtagttt caaagaatgg aattgactta aacttaacac atacagaatt tgaaattgtt
     1621 aaattactag cgactaatca aggacgtgct ttttcaaagg aacaattata caacgctatt
     1681 tggaaagaac cttattatgg aaatgaaaat gtgctaaata ctcatattaa caggttaaga
     1741 aataaattgt ctgatggtat agaaaaaaat aattatatta aaactctttg gggaattggc
     1801 tacaaaatgg aggaagaata atggagttat ttttagttgt aatttcgatt gtactatttg
     1861 ctctctactt aaaagaacga aataaatcaa agaaaatgga aagtgattat aagtatatca
     1921 attcaagact tcgtgacata acaaatgatg atgaaattaa ttatatttta gtaccatctg
     1981 atatttcgat tgtaaaagaa acagcagtag atataaataa acttgttgaa aagttttaca
     2041 gcaggcaaat taattataat agaagtgaaa aagcgatatt gcaaatattt acaaacatat
     2101 cacacgattt acgaactccc atcacagtat taaagggtta tattgaaatg ctatatcttc
     2161 aaagtcaaaa agaagaatta tcttcttcaa tgagagcaat tgtggaaaaa atgcaaacaa
     2221 attcaaatga gcttgttaat tcaataaata acctgtttaa tatggcaaaa atccaatctg
     2281 gagatatgat attaaatctt caaaaatcca atctaacaca attatgtcat gagattattt
     2341 tagagtttta tgatttgcta gataaagaaa actttaatgt tgaagttaat attgaagata
     2401 gacctatata tgcaaatgtt gacacagaag cattacaacg tatactcaaa aatttaattg
     2461 ataatgctat aaaatatggt tcagatggta gatttttagg gatttcacta tatgaaaagg
     2521 aaaaacatgt ttttatagat attgaggata aaggttcagg tatttctgaa actgaaaaag
     2581 agcatatttt cacaagagct tatactgctg acagaaaaaa aggcaatggt ttaggtttgg
     2641 ctatttctca agggcttgca aactctatgg gaggttcaat ttatgtaaat agtagaccta
     2701 atgtaaaaac agtttttacg gtaaaattga aaagttagaa aaaagttaga tttaaaagag
     2761 agaaaagaca attttatttt gtatactgtt tttagaaagg agggagtatg atgaactata
     2821 tcatagagac ccatcaatta aagaaaatat ataaagataa agctgttgtt aatgctgtta
     2881 atattcatgt gaaaaaggga gaaatttatg gatttgttgg accaaacggg gcaggtaaaa
     2941 gtacagtaat gaaaatgttg ctaaatcttg ttaatccaaa ttctggagaa atagttatgt
     3001 tcggtaagaa agtggcagaa actgattttg aaatattaaa aaagattggt actattattg
     3061 aaaatccgta tttatatgag aatttgactg ctaaacagaa tcttgattta cactgtgaat
     3121 atatgggtta ttataacaaa gaacatatat cagaggtatt ggaatgtgtc ggattgtcaa
     3181 agcaatcaaa caagaaagtt tcaaaatatt ctttagggat gaaacaacgt cttgcaatag
     3241 ctagagcaat tcttactaaa ccagaattat tgattcttga tgaacctata aatgcactcg
     3301 acccagaggg gataagagaa atgcgagaat tattccgtaa gttaaataca gattatggaa
     3361 taactatatt tatttctagt catattcttt cagaggtaga acaaattgcg gacactattg
     3421 gaattattca agatggtaaa cttattaaag aaatttctat gtcagatata cacaaatatc
     3481 aaacagatta tgttgaagta gatgtagata atgtggagct tgctggatac ttgttagaaa
     3541 aagaatttgg aataaaagac tttaaaatta cttcggaaag ttgtattgaa atatatgatt
     3601 tacgaaaaga tgtaaaagaa atatccaaaa tatttattca aaatcaaatt ggtataaata
     3661 gcattggacg taaacaaagt tctttagaag attacttctt ccaaactaca ggtacaggag
     3721 gtaaagaaac actatgatac atttaatgaa actagagcta aaaaaagttg ggctaaaaag
     3781 atatttttta ttttcaatgc tggggatttt cttatgtatg ttttttgtct ttactggatt
     3841 gaatgataaa tctacttcaa tatatgatta tgatgttaca tttaggacaa tcagtttatt
     3901 tttctgtttt tactatatta tattatttgc tgtgttgaat gtggcatata taataaatga
     3961 atatacaaat aaaacaatct tgattttatt ctcttatcca cttgaccgta aaaaacttat
     4021 tttatcaaag ttacttttga ttacgactct tatgatatca tcaatgatag ttggatatat
     4081 ctgttgtttt acattcgttg ttgtgttgga taagtatttt aatttagtta ttggagattt
     4141 tcatatttca attttatctt attggatacc aggagcaatt aaaagtatta ttgtattttg
     4201 ctcattaggt atatggacat tcgttgttgg aatgataaga aaatcaatac ctgttaccct
     4261 tgtcagttca attattttta tcaatttaag acaatttatt ttagctggta caaatacaac
     4321 tcaagacagt ttgatttctg tttttattat agttggtata actgtgattg gtatatatta
     4381 tatactaaat cataaagtta ctgaaattga ctagatactg tggataggag ggtagttatt
     4441 aattgtatct tcttgggata ataatgattt gctattatat cagctattat taatattatt
     4501 agagttttaa taatattgca caaccatttg aagttgagcc aaagcttgat gaattaattg
     4561 aatggtacta tagtcagagt gaagtatcta ttaaagttat agctgaattt cattatagat
     4621 ttgaattgat acatccattt caagatggta atggtcgcat aggtagattt gttatgctaa
     4681 aacagatgtt agaaaataat cttcctataa aaattgtatc ttgggatagt gaggaattgt
     4741 atagaaactc cttaaattct tgtagtttag gtaattatgt ccctttaatt gaatatttat
     4801 caagtttaga agattttaga gaagtatata aaatgttatg gaaataattg tttgcagcaa
     4861 aaaaagtttt tatataaata tatttttatc tatgctattt aacgctaatt tcttagttat
     4921 tcttagcttg gactataccc actattttaa ctatataaaa tagtggatat agtttaacta
     4981 tctctttata actattttta tgtatcttag ttgtttctta atatggggac agttcataaa
     5041 actaaaagtg atttttaatt ttatcattta taatttacca ttacatcaga aaaatgctta
     5101 tcattagaat tttcataaaa ggtacctatt tttttcaatt aactgaatca attctattag
     5161 tcttaatctt tcatatttca aattgataat ataagaaaat aaaaaataaa aaattttaaa
     5221 ttttttattt attgcgaaaa aaataaaaag gtgctatact ttttgtaaca tattattcaa
     5281 attattaaga gatagtaaac atttatagtt taatttgtag tacactagca tgatttgcag
     5341 aacaatgaat taatctatag tataatagtt taatttaaag tacaacgatt taatctatag
     5401 tacactagca tgatttgaag tacaacgatt taatctatag tacactagca tgatttgaag
     5461 tacaacgatt taatctatag tataatagtt taatttgaag tacaacgatt taatctatag
     5521 tacaataact tgatttgaag tataacgatt taatctatag tacaataact tgatttgcaa
     5581 tacaatgaat taatctatgg tataatagtt taatttgaag tacaatgaat taatctatag
     5641 tataatagtt taatttgaag tacaacgatt taatctatag tataatagtt taatttgaag
     5701 tacaatggtt taatctatag tataatagtt taatttgaag tacaacgatt taatctatag
     5761 tacaataact tgatttgcaa tacaatgaat taatctatag tataagagca tgatttacag
     5821 tacaataatt taaattgtag tacaaaagta ctatcaaata agaatttcta ctttaaaaat
     5881 attactaaaa gtaattaaag tccagtaatt caatataata tggcaaaaga atagaaataa
     5941 ggtgagagta gtgaaagtaa agtcaaattt agatgaaatt ttatatcata agattattga
     6001 aagtcttatt cgtggtgaat actctgtagg tcaaaaaata ttactaaatg acctttgtga
     6061 aaaatttgaa gtaagcagaa caccagttgt acaagcagta aaaatgctaa ataaagatgg
     6121 agtgcttact attatgacaa atggtaaagt gtacgtacca gagtatgaat atgatatggt
     6181 aaaacaagtt tgtgaaacga gaacactgat tgaaacatat gctttagaaa aaatgatgca
     6241 agaagaggaa gaggtttttc aacaaaagct agatgtaata aaaagatact ctgataaatg
     6301 cgaggagtac tatcgtcaag aaaaatctgt agaacttgca ctagcagatt tggaattaca
     6361 taaagccatt gtagaagggg caaataatga gattttaaat gatgtatatg ttggtataca
     6421 aggaagattt atagtagtga actatttaat tcgaccatta aaaaatcgta attatgaagg
     6481 aacagtacaa gaccattttg aaatattaaa attcattgaa gacagagata caaaaaaagc
     6541 agtagataaa ctaagaaatc atattcaagg aactattaaa agattctgtg aagatgaata
     6601 ataagttttg aagttactat atatacttat ctattaagtt gctaaatgta gtctaagtat
     6661 aatctaatta tagtttaaac ataatctaaa tataatctaa taaatataat ctaaatatag
     6721 tgtaaataag tctaagtatg aattaaatat agattaagta tagattaagt atagattaag
     6781 tatgaattaa gcatgaatta agcatggatt aaatatactt taaattacaa atattacaag
     6841 gaagccagaa ggcttcctaa aaaaataacc tttataaaat tttttatttt aaatttaaaa
     6901 ttttttattt taaatttaaa ataaaaaatg aaagaggtgg tagagagttt gaaaaaaatt
     6961 actaaagaaa ggatagaaaa tactatgaaa aagctattta cgagtgaaac atttttggaa
     7021 tatcaattta taagtgattg ccaaatatca ccagatggag gatatacagc atttattgta
     7081 aaaaaagctg atatcaaaga gaatggttac acaagccaag tttatatatt aaacaataaa
     7141 actggcgaat taaaacaaat aacgtctata aactctgttg gagcatatgc ctgggaagat
     7201 gaaaatacta tcttgttccc tgctttgcga aatgaaaaag taaaagaagc tgtcaaaaac
     7261 ggtaagcaat gcatgagtta ctatgcttta tctttaaatg gtggagaagc agaagaactt
     7321 tttagactcc ctatcaaagg tggtaaattg aatcctatag gaaaaggttt gtatgcagtt
     7381 attgattctt atgacaatga ccgacctatt gtagagggat tgccagaaga agaacaacag
     7441 aaaaaaataa atgcttataa caaaagacat tatgaacatt tcaaagaaat tccttatgct
     7501 gtcaatgggg agggatatat tagcagaaaa agaaaacgcc tatatgtata cgacagtaat
     7561 ataaatgagt tgaaggcaat tacagcacct atgtttaatg ttgtaggtat gaaaataagt
     7621 gatggaaaaa tcttatatat agggcaagag tttaaagatg taaaaggttt gaaaaatggg
     7681 gtctatgtat ttgatacaaa cacaaacaca aatgtctgta tattagaaaa agataagtat
     7741 attataaaag gttttgaatt atatcaaaat caagtgatac taaacctaac tgatgcttta
     7801 tcttatggaa atggagaaaa tggagatttt tatactattg atattgatac gaaagaaatg
     7861 aaacttcttt cagggcatca acatcattgt attggaaata cagtaacatc tgatgttaaa
     7921 atgggtgctg gtcagacaac aaaggtagat ggagaatata tttattacac ttctacagta
     7981 gatatggact gcattattga aagaatacat attccaacag gaaaacagga aaaagtaaca
     8041 cagacaggtt cagttgattt tatagatgta aaagatggca atattgtatg tgtgggttgt
     8101 ttaggaaatg gattaccaga agtttataca gtagagaatg gaacattgtg taagaaaaca
     8161 catttaaatg accatatttt agaggaatat aaaatttctg tgccagaata catagagtca
     8221 aaaggaagtt ctaaatggga aatacaagga tacgtatata aaccagtaga ttatgaggtg
     8281 gggaaaaaat atccagctgt attggcgatt catggaggac caagattgac atatggacca
     8341 tattttatgc atgagataca ggtatttaca agtgcaggtt actttgtatt cttctgtaac
     8401 ccaagggggt ctgaaggtcg tggcaatgct tttgcagata ttaggaaaca gtttggagat
     8461 attgattata tagattttat ggaatttaca gatactgtac ttgaaaaata tacagacatt
     8521 gataaaacaa aattggctgt tgaaggtgga agttatggtg gatttatgac gaattggata
     8581 attggtcata caaaccgttt tgctgttgct tgtgctcagc gttctattgc aaactggagt
     8641 ggcatggagg gtacaacaga cattggttat tatttctgca aaggacaaac aggtgcttct
     8701 catatggaaa accacgagct tcaatggaaa cagtcacctc ttgcttatgc tgataaatgt
     8761 gttacaccga ctttattttt acatggtgaa aaagactata gatgctatat gcaagaagca
     8821 ttccagatgt tttcagcatt gaaaattcat gggtgtccta caaaactttg tctatttgaa
     8881 ggagaaaacc atgaactgtc tcgttctggt agaccaaaac aaaagctaca aagattagtt
     8941 gaaatgctag attggttttc agtatatata aaaaaagata acataggaca gtagaaagga
     9001 gaatataaaa atggaaaaaa taaagattga aagttcagat atttttgaat atatattccc
     9061 tcatgatatt tcttgttcac ctgatggaaa gcatattgct tatattatat caaatatcaa
     9121 cgaggaaaaa gactgctatg aacatgactt atatgtgatg gacatcaaaa cagaaaaaca
     9181 aatacatatg actcaaacaa aagatgtaac atcatttagt tggatttcta atacagaact
     9241 cctttttaca tctaaaagaa ataagccaaa atcaggtaca acagattttt acactatttc
     9301 tatagaagga ggagaagcaa aaaaagcatt ttctattcca aaagcttgta gcgtacctgt
     9361 atcacttgga aataaattgt ggttactgac aacaaaaaat ccaacggatt ctaaaaaatc
     9421 agaaccagat agggcagtag agggtgtaga ttattggaca tttacagata aaccttttat
     9481 aagagatgga gaaaattttt ctcaaagaag acgtgtaaca ttagaattat atcaagaagg
     9541 tgaaaatata acaaaagcca ttacaccaaa attttgtgaa gtagcaggtg tagacgtttc
     9601 ttctgataaa aacagaattt tatatactgg tcagatttat gaagattgtg caactccttt
     9661 ttctggactt tgggagtatc atatagacag tggtgaaacc aaagaacttg taccacaagg
     9721 aaagtaccaa ataagtttgg caaaatatat tggcaaagat aaagtaatgt tgcaagcttc
     9781 aacattagac cgttctatca cacagaatca tgatattttt atacttgatt tgagtactaa
     9841 tgaaataaat atgattgcta gtccagatgg tatgtatgct acattgctgg atgtagatgc
     9901 agtatatggt ggtggacgta gtaataaagt tataggagac aaatttattg gtgcaagaat
     9961 ttgcagaact atgacagaat ttaatgagtt tgatacaaag acaggtaata tacgtatcat
    10021 cacaaaagta gatgctttta catcttttga tatttacgac aacaccatgt acacagtaat
    10081 gttgaaagat tatgagttag cagaaatata tagcattgat atgactacag gtacaatgaa
    10141 aaaaatgact gctttttcta aaccatattt agatactcat aaggtttcat tacctgaaaa
    10201 attgacgttt gtagcaaaaa ataaagaaga agttgatggt tttgttatac cacctataga
    10261 tgctaaagaa ggcgaaaaat atcctgctgt attgttcatt catggtgggc ctaaatgggc
    10321 atatggctat atgtttacac acttgaagca gtgtgtaaca tcaaagggaa tgtatgtgat
    10381 ttattgtaac cctcatggtg gtgacggtta tggtgaaaaa ttcttagaaa tggtagaaag
    10441 atgggggtat gttgactatg agcatcttat ggaatttgta gatacttgta ttgaaaaata
    10501 tcctgggatt gatgcagacc gcttaggggt tgcaggggga agttacggtg gttatatgac
    10561 aaactggata attggtcata cagaccgttt caaagcagca gtttctcaaa gaggtattag
    10621 taacttgatt acagcttctt taattattga ctttggggat agaattatga agcagacttg
    10681 tggagataag acgccttgga atcatgagga ggttctttgg aatcattcac ctattaaata
    10741 tgtgaaaaat gttaagacac caacattgtt cttacatagt gatagggatt atagatgttt
    10801 tatgggggat actttccaaa tgtttacagc attaaaacag cttggtgtag atacagaaat
    10861 gtatttgttt catggagata cacatggatt gtctagaaat ggaagaccat ctaatagaat
    10921 tgcaagagca aatgctattg tagattggtt tgaaagatat ttataataag ggggttattc
    10981 tatgagtgat atgttattat ggtttagtgt cgtattagtt ttatttgcta ttggggattt
    11041 aattgcaagc aaaacaaaag caaaagtatc agctgtattt gttacactac ttttattttt
    11101 gattctattt gtcacaaaag caataccagc tgatattatt gaaaaagcag gtatgaccgc
    11161 agcagctagt tggagtgttc caatgattat gtttagtatg ggaacaatgt tgaatgttaa
    11221 acaatttata gacgaatgga gaacagtatt gacagcatgg cttggaattg tagcagttat
    11281 agtctgtgtc tcattatgta ttcctttgtt tggaaaatca acagtattga caagcatacc
    11341 agttataaat ggagctttac ctgctactac tattatgaca caagcagcac tagaaaaagg
    11401 actgacactt gcagcagcta cagcaacagt tgtatttgca attcagaagt ttattggtac
    11461 accaatagct tcaagagcag cgttacaaga ggcaaaccgt cttttagtag aatatcatga
    11521 agcaaaatca aaaggcattg atttagcaaa tgttgatact gataagaaag aagcagagaa
    11581 tacaggcaca aaagtaaaac aagctttctg tgaaaaatac gataaatatt attctacaaa
    11641 tgtttgtata ttttttatag cattattctc ttatctaggg tatgaacttt cagagattat
    11701 tcatgtaaat tattctattg tatgtcttgt tgttggtgtt attgtaacac gtattggtat
    11761 tgtgccaaaa gacattttgg aaaaaggaaa aatcaaggga tttatcaaca tggttgtgtt
    11821 tgcagctgtt attccttctt tagcaaaagt ttctttgaca gatttaatta gtctttttgt
    11881 accaattgtg ggtatgtttg cagcttctat cattggtata ttccttatga tgaaggtgtt
    11941 accaggttgg aaaattatcg gttctaaacc tcttgctttt ggagtagggt tttgtcagat
    12001 gttgggattc ccaactacat atttaatttc aaatgaagtg tgtaatgctg ttggagaaac
    12061 ggaagaagaa agagcatatt tgatgtctaa gattatgcct aagctggtag ttggtggtat
    12121 ggcttgtatg atttctattg tggtagctgg tcttatggta ccaatgttgt agataggttt
    12181 catagttaaa aaagtggtat taatttatag gagaagctaa aaagtagtat taatttataa
    12241 aataatttta tattagttaa tttgttataa gaatattttc tttttataat tataattttg
    12301 attttataag atagcagatt ttttatttgc tatgctaata gttataattt gtttttattt
    12361 gctaaaatgc aactttaatt tgatttatgt ataatatagg gtatttaata atatttttga
    12421 agaattttta taaaaaatta aaaagaggag aaaaaaggga gtgccacaaa gtgaactttt
    12481 tagttctaag gcactctttt ttgtacgaaa tcgaatatat tttcaacgtt ttaaaagtga
    12541 gaaagagact tatctctagt ttgagatagc caattttaat tattaaaatt attttttgtt
    12601 ttatttatca aagagtattc gtgttttaga agttagtatt ttttatttta tatatacaag
    12661 gttttccgtt tctaatgttt tcttttttaa aataattagg gtattcaatt atagtaaaag
    12721 gtggatggta ttttggagtg atattattta aagcacagta ttgaatgttg aaatcctcac
    12781 attttagagt attatctttt gtaatcaaaa aaatcttcta tacttatagc aaggttactt
    12841 ctgcaaatat tccatacata ataatatccc aatttaaatt tttttaatat agagtttacc
    12901 tctagtctac actcttgaat aactctttcc tctatccaaa ttcttataaa ttcatcccat
    12961 ttattactat ttatttatta ttatctaaat tttttagtat gtttgtaatt agaaatggat
    13021 ttattccttt atgtttttta taaatagttt ataacttaat ttatcattaa acaaatcatt
    13081 catacaggat tactttttct tttatatatt caattcttac ttttaataaa tatttaatac
    13141 atcctatctt atgtagtttt aaaaagtgtt tatggctatt aacaatctct aatatttcat
    13201 tcatatttat tttgtcatag taatatttta catcttttat attgacaaaa aagtgctcta
    13261 agtgtatagt gtgtatatga taacatcaca ctgaaagtga taaaaagggg gtgataaaaa
    13321 atgaaagtgc tcatttctaa cacatcagat aagccattat accaacaaat taaagagcaa
    13381 attaaagaag caatatttac tgaagaactg aaagaagggg atgcaatgcc atccataaga
    13441 aattttgcta atgatttaaa agttagtatt ttgactatta gacgagtgta tgaagaactt
    13501 gaaaatgaag gctttcttac acgccaagtt ggaataggaa catttatttc aactggaaat
    13561 ttagaaatac taagagactc aaagagacgt atagttgaac aaaaaatggc agatatgatt
    13621 aaagatgcaa aagcactagg aattacacag atagagttac aagaaatgat ggatattcta
    13681 tatgaggagg attaatatgg aaaatatttt agaagtttat aacttaaata agacttatac
    13741 cgatttttca ttatctaata taagctttgc attaccagaa gattgtataa ccggatttat
    13801 aggtgttaat ggagcaggaa aaacaacaac aatccgttcg atattggatg tcgtaaagcg
    13861 tgatagtgga aaaataaaaa tctttggtaa agatttcgat ggaaatgaga aggaattaaa
    13921 aaatcgaatt ggagttgtct ttgatgattc atatttctat gaggagttgt caatggcaga
    13981 aatgaaaagt attattgcac cttcatatga taattggtgt gaagaagatt atcaacaaaa
    14041 tatgaagcgt tttaatctta acccaaaaca aaagattgat acactttcaa aaggaatgaa
    14101 aatgaaattt gctttagcat tagcattatc gcataaagct gagtttttaa ttatggatga
    14161 gcctacaagt ggtttagacc cactaatccg tagtcagata cttgacatac taacaggata
    14221 tatgaagaaa tgtggtcgtg gtgttttctt ttccactcat ataacatctg atttagacaa
    14281 aatagcagat atgattgtta tgattgacaa tggacgtatt atattagagc gtgaaaaaga
    14341 tactctattg gacgaacata gaaaagtaaa aggggatatt caatttctaa atgatgaaac
    14401 caaaaaatta tttttaaatt tagaaattac aggttatggt tttataggga ttacctcaaa
    14461 aattaatgaa gtgcaaaaaa atatgccaga tattttaata gagcgtccta caattgaaga
    14521 tattatgctt gcatatattg aaaggagaga gtaattatgt tgattcattt agttaaaaaa
    14581 gatattctga ttgtaaaaaa atatgtattg ttgatattat ttattgcaat aggaatccca
    14641 ttatttatat tatggcgttt acctccattt gcacaaatat tgggatttgt actatcaatt
    14701 atattttcag aatttatgct gtgtcagtat ctattattaa aggagagtca atattcaaaa
    14761 gcatctgtat tactttgttc aactccttat cctagacgtg gcttagttca atctaagtat
    14821 gttttatttg caatggtatt tatctattgt acattagttt actggattga aaatttactt
    14881 attccacaaa taggaacttt tgacttgaca tatattttga ttgttttatt aataagttct
    14941 attatttatg gagtttatat gcctattcaa tacaaattag gatatgaaac aacaaaattc
    15001 tttttcgtga tgataatcat ggcttcatca tttgtattac cattaactat agctcacagc
    15061 aattttgaaa ttccatttat atatcagtat ccatccatga tagtgaatat tgtattgttc
    15121 cttttaagtt taattatact gttagcttca atgtttattt ctattaaaat ttttagtaat
    15181 aaggagcttg tataaggtaa gggggacttt tatatgccac atttaccaga ttgggctgtt
    15241 ttactttgta tcttacttcc aatagtatat aaagcttgtc agatatttaa aagtaaaaaa
    15301 tagagtatat atttatattg ccatttttat tgagtgaagt tagatggtat gaaaaggtta
    15361 cttgaaaata aagttacttg gtgtgggaga gtaacatcat aatattatag attatatgtt
    15421 tcttgtgaat caatttgtat tttttaatag ggaatatcca gtaattttgt tttccattga
    15481 ttatttttca attatgagta tgattgtgtg tattgtatac catcttttaa ggtgttttta
    15541 aaaaattata tcgtcaaaat ataaatctaa ggaatcctat aaataaagct ttttaatttt
    15601 agaaaactaa taaaaagtag gacgttaata aaaagaagct gtctcaaaat agagataagc
    15661 ttctttttca ttgctgaaat gacgaaaata taattgattt aatataaaaa agagtgcttt
    15721 atgaactatt tattttgaac agtagataca cttgcactca atttagttac tcctaagctt
    15781 tatgaactaa aagtttattt tgaagcttat ttttattaaa agagatttta tttttctaaa
    15841 taatcatcta tatacagtat tgcgtttctt ttatttattc ataatttatt ttcttattaa
    15901 agtttttcta tattcatatt ttctatatta ctttactttt aattttatac gaattatcaa
    15961 aaataaaata gttattagaa aaaaataaaa gtaattgcaa agcttgcaat tacttacttc
    16021 tatattaatt actataccat aaaataacaa aaaaatcaag tcgagtaatc cttcaactta
    16081 aatgatatac taggtattaa taatttttaa ttaataaaat ataactagag gaaaatctac
    16141 attttctcaa tttctttaat taaattgacc tctaattaag taattataag gagaaaaatt
    16201 atgaatttag caaagggatt agatgtttta aaaatttcat caaatgtatt cggtgaagat
    16261 aaagttatgt atattcctgt aatctacaca gaagatgatg caacacttat tgacacaggt
    16321 cttccgggtc aaggtgattt aataattgat gctcttaata aaagtaacac gagctttgat
    16381 aagttaaaaa atataataat cactcatcat gatatagacc atataggaaa cataaattat
    16441 ctaagagaaa aatctaagaa taatatcaaa gtatatgcat acaaaagtga aatcagctat
    16501 ataacaggag aagaaactcc ttttaaactt tatatgttgg aacaaatggt agataaaatt
    16561 gatgataaga tgcttagtat gctaaatgtt atgggacttg gatttaaatc atcatatact
    16621 aaagtagatg tgtcattaga taaccatgaa aaattgaatc taggtgagga aatagaagtt
    16681 atacatacag gaggtcacac tagaggtcac atatgtcttt atttaaaaga gtctaaagta
    16741 cttattgctg gagatttgtt acaggtagaa aatggagaac ttaagcctgt tgatgtgatg
    16801 tacagcaaca aacaagagtt aaaagatgct attaaaaata taagtaatta tgatatagaa
    16861 acgatagttt ttagtcatgg tggattatat caaagaaaca taattggaac attgaaaaac
    16921 ctaattattg agtagtacta tatgatttac aataatttct taaattactt aaaattatat
    16981 ctaaagatgt agaatcaaaa ttaaatataa gtaataagaa ttttgcttta aaattatact
    17041 taagtgttaa gggtgatatg tagtattaca agtattttag aatataattt tttatagtaa
    17101 ttttaaagtt ctacaatact tcagttgaaa aatatttaac agcatagtat aataggaaag
    17161 aaaatatttt aaataaactt tagtatacaa agtgaagaaa aatatttaaa tcatgtatca
    17221 taatgcaaag taaagaaaat catttaaatt atata
//
LOCUS       DAGQVA010000085        16938 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.085, whole genome shotgun sequence.
ACCESSION   DAGQVA010000085 DAGQVA010000000
VERSION     DAGQVA010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16938
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.085"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(106..2244)
                     /gene="vanT"
                     /locus_tag="MIV85_003127"
     CDS             complement(106..2244)
                     /gene="vanT"
                     /locus_tag="MIV85_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBY2962449.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(2262..3068)
                     /locus_tag="MIV85_003128"
     CDS             complement(2262..3068)
                     /locus_tag="MIV85_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBY2962450.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(3065..4165)
                     /gene="vanG"
                     /locus_tag="MIV85_003129"
     CDS             complement(3065..4165)
                     /gene="vanG"
                     /locus_tag="MIV85_003129"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBY2962451.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(4426..5508)
                     /locus_tag="MIV85_003130"
     CDS             complement(4426..5508)
                     /locus_tag="MIV85_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2962452.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            complement(5558..6259)
                     /locus_tag="MIV85_003131"
     CDS             complement(5558..6259)
                     /locus_tag="MIV85_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBY2962453.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(6693..9224)
                     /locus_tag="MIV85_003132"
     CDS             complement(6693..9224)
                     /locus_tag="MIV85_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBY2962454.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(9332..9949)
                     /locus_tag="MIV85_003133"
     CDS             complement(9332..9949)
                     /locus_tag="MIV85_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBY2962455.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(10311..11195)
                     /locus_tag="MIV85_003134"
     CDS             complement(10311..11195)
                     /locus_tag="MIV85_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBY2962456.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(11386..12636)
                     /locus_tag="MIV85_003135"
     CDS             complement(11386..12636)
                     /locus_tag="MIV85_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2962457.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(12858..13622)
                     /locus_tag="MIV85_003136"
     CDS             complement(12858..13622)
                     /locus_tag="MIV85_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962458.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(13616..14341)
                     /locus_tag="MIV85_003137"
     CDS             complement(13616..14341)
                     /locus_tag="MIV85_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962459.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(14343..14711)
                     /locus_tag="MIV85_003138"
     CDS             complement(14343..14711)
                     /locus_tag="MIV85_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2962460.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(14887..16431)
                     /locus_tag="MIV85_003139"
     CDS             complement(14887..16431)
                     /locus_tag="MIV85_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBY2962461.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT         5785 a         2973 c         1688 g         6492 t
ORIGIN      
        1 gtcatgtaag ttataaaaaa tatatattag acataatatt actaaaaatg tctagtcaga
       61 gtaaaataaa ttacacagta caacaaatat tactatttaa ttgagttact tctttataac
      121 atttaacctt cttcctactc tgctcaataa ttcattcgat atactacatg agttatttgc
      181 aacttcagaa gcagataatt cagataaatt atctcttcct attattattg ccgtattacc
      241 aacttctaca ttaggtatat ctgtaatatc aacagcaagt tggtccatgc aaattcgacc
      301 cactattgct gctctacaac catttattat tacgtaactt tttccacagg ataaatttct
      361 aggtatacca tcggcatagc caatagataa tatagcaatt acgctatctc tgcttgcaat
      421 aaagactctt ccatatccaa aactatcatc tttttgtatt tttctaataa gaattacttg
      481 tgattttaag gataaaacag gtcgtaaatc aagttgcaat ttagtcgtat catttggaga
      541 acttaatatc ccgtataatg caattccaat tcttacataa ttacacttaa gattgggata
      601 attaaaaaaa ccataactac tttgaatatg tactttagga atttttatac ctttttttaa
      661 cagaaaatca attaacttat aaaaacattc aatttgttta tttgtaaagt ctacatcttc
      721 atctttcaga ctatctgaaa cacacaagtg tgtaaatatg ccacatatat ctaagtattt
      781 taatttaaat gcctttaaaa ttgacctcac atcattaaca tcaaaaccca gtctgtgcat
      841 acctgtatca attttaatgt gtgattttat gttgtatttc tgtttgttta aagagatagc
      901 atgattaagg tcaataacac tctgtgtaag attgtattta tgaagttcct ttgcccttat
      961 tgggttagta tatccaagaa tcaatatttc tcctagtatt ccatatcgac gtaaatcaat
     1021 cccctcatct attgttgcta ctgcaaatgc ttttacacct atttggtttg cacaagtcgc
     1081 tacttcaaaa gcactatgac cataggcatt agcttttaca actgccatca attcacaatc
     1141 ttctggcata gctttttgta tcatctttac attatgttcc aaattattta aatcaatttc
     1201 aatccaagct ctattggtat ttaccttatg ttctcctttc aagtcttttt ttagaggttt
     1261 aagaatcaat ataataatta tagaagctat aaaagatgct atacttacca ctatataatg
     1321 aataaggcta ttgtcaacca agacagtttg tattccgaat attttagaaa acatacgaat
     1381 aacaacaatc atcataggat gtataatata aataattaat gatgatgttc gcaataacct
     1441 agctcgagaa cctttcaaaa atgttaaggc tgtaaataag aaatacatac atggcaataa
     1501 cataatatac atgctatcat gacgctgtac ccctagttta tgtaaaaaca ttccctcaca
     1561 taacataagt aagaatgata taagaaatcc aatcaagcta tttttagttg acatataatt
     1621 agatttatta gatattattc caccaagtat gaaaaataca ggtgcaaaaa atataccatt
     1681 tcgtgtataa tctgatactt caaaaatata cccatataaa ttctttaata gtggtatttt
     1741 ttctaaaaaa ccataataac tatcaccaaa cataccaatt acataaataa caatagtgat
     1801 tactagtgag tactttaaac ctagtctttt tacaagaaag tatgcaatac ttgcaccaat
     1861 aattgatgca ggtagatacc ataaatgata taaagtccca tcaaatacaa tgtccttaat
     1921 aatattgggc actaaattat tcatggaaaa atatccagtg taaatattta agggaatata
     1981 aattacaata gctatcccgt aaataaataa tacatttttt agaaaagatt tcagtttatt
     2041 acaattataa ttatatgttg aaattagaaa aaagcctgat agcataaaaa agaatggcac
     2101 agcaatacga gcaattatac tagttaacac aaagtcagcc attttactat atgataataa
     2161 tggagatgta tgaattgcaa ttataagtaa tgcagctata atcctaaaat aatcaagccc
     2221 tgcataagat ttattcctaa tcattcttgt tcctccattt cttagtcctt tctatttctc
     2281 caaaatgtca caataaaacc atccttattg ttacccgata tttgatatac acattgttca
     2341 ggtatagaga ttctcacttc ttctttagta tgaataggca cataaaagat ttctataatt
     2401 ttttctttat cttctatttt taaacaattt gtatacgaaa atctcttaat atattctata
     2461 tattcttcaa gagcgagatt cattttattg ataatctcag aatgcggata tcccacataa
     2521 cgaaaatgcc atggttcttg agatattcct gttatttctt cttttttaca ctgataacgc
     2581 tctataaaac cataatgtag tgctgcctta cgaaactcat tacaaatacc attataagga
     2641 aattcagggc agataaaatc tataacttct ttctttaacc ctaaatcaat agcaagccct
     2701 gtctgatgtt cactgtgatt tggaagtgct acaaactttt tagtaaagtc ttttccattg
     2761 tcacgcagag aacttgaata tatatcttgt tgttcctctg cagtacgata tccacttaca
     2821 ggtactattt catttattcc acatatactt tttaaaatat tttgtaaaat gtttgtagct
     2881 tcacgtttca taagaatact tggaaacctt gtatctacag gaattaaatc tatatcttca
     2941 gatgttttaa ctggtaaaaa agcatttact agaattagat tcccatcata aactttatct
     3001 ttagtcaata agatagtatt tgtcatttta tcttctttat ttttatctaa taaaatatta
     3061 ttcatcattt tatgtacacc tcaattatct tgtccaatat ttcttcaaaa gacaatccaa
     3121 tacctttcat catatttgga taacgactat gagaagtaaa gccaggaatt gtattgactt
     3181 cattaaaaat aatttcacca gatggagtta aaaacatatc tactctagca aatccagaac
     3241 atccaagagt tctataaata atttttgctg tctcttgtat tcttttctca caatccaaat
     3301 caattctagc tggcatatga atttttgaac ttttcaatgt atatttttct gtataatcaa
     3361 aaaatccttt tgacaattct atttcatcta ctcttccaac aagtaagtca tcgtttccta
     3421 aaactgcaca ccctacctca aaaccatcaa tattttcctc aattattact tcattatcat
     3481 gttcaaaagc caagtctact gctacttgta actcttcttt tttataaatt ttactaatac
     3541 caaatgatga acctgcacgc acaggtttta taaataatgg ataagttaag tcttttgaca
     3601 gttcagccac attaaattta tctgagtatt ttagtaatat tgattttggt actttaatac
     3661 cttctgaatg aacaagttta tgtgatttgt ctttgtccat acataatgct gaagaaagag
     3721 taccacatcc tataacctgt atacctgcca attcaaataa cccctgcact gttccatctt
     3781 ctccattttt tccatgcagt acaggaaaca caaaatcaag tttagtgtat ttaatatcat
     3841 tttcacatga ttcaatagca ctatttggaa tatgattctg agaaacagca tcaggaatta
     3901 aaaattcaat aataccattt ttgacacggt tctgcgaaac aataactgga attatatcag
     3961 tatccctttc aaaccaagtg ttattctgga tattattata atctccaata taatgatacc
     4021 aattaccctc ccttgtaatt ccaattggta taatatcata tttttccgta ttcaaattct
     4081 caagtactgc aaaagctgat tgtaatgata catcatattc tgttgagttt ccaccaaata
     4141 taactgcaat ttttttatta ttcatctttg attctccttt gttgatttat ttatttttat
     4201 acaatctaca gaaacatgtt aaaatacttt ttctatttca aatccaatca accttcactt
     4261 acaattgcat ctgttccaca taatatattt tcacattttt ctattgatat aattactgta
     4321 tcaaaataaa agcactcttg ttttgataca gtaattatat caataacaag agtgctcttt
     4381 atttatttat cctaaagaat ttcctatttt tttatactta aattcttaca aatttcctac
     4441 aatcggaata ataaccttaa agataattat attgttctcg ctatgagctg ttattgtccc
     4501 gttatgaagc tccactattt ctttagctat agcaagtccc aacccagctc taccactgtt
     4561 tgaattacga gatgtatcca acctgtaaaa ttgttcaaaa atacgctcaa gtttttcctc
     4621 tggaatcgta ttgctatgat ttataaattt aagctttata taatcatcct cctgtacagc
     4681 tgttatttca atagtagtat cttcaaaact ataataaaca gcatttcgta ataagttatc
     4741 aaatacacgt tgcattttat taacatcaca ccttatcatc atatttggtg taacattcag
     4801 tgtatatttt aaattcttac tcatcaaagt aggtttaaac tcatatgtta gttgttcaag
     4861 catacgagtt aagcttactg tactgtattc aagtgatata tttgataaat taaaccttgt
     4921 aatttcaaag aattcattaa ttaaatcttc aagacgctct gccttatcca acgaaataga
     4981 taaatatttt tttcgcagtt cttcagaaat ctgactttca tctcgaagta gtgtcagata
     5041 ccctataact gatgtaagtg gtgtttttaa atcatgtgca agataaacaa taagttcatt
     5101 cttacgttgt tctgccattt gtgtctcaaa tttacgttgt tcaagtatat gtttaattga
     5161 gtttattttc ttttctattg ccaataactc tggagataaa gccacttctc caacatcttc
     5221 tttgataaga gagtcaatac cttgatttat ttcactaaaa tattttgtaa accaatttaa
     5281 ataaacccgg aatattataa aaaacacaat caccatagct agtatcatga agagctccat
     5341 gctattacgg aaaatctgct gatataaatt caatgcagct ttatattcca tacgaaaagc
     5401 attttcaaag aatgatacta tccagataga aaacttacca tacaatataa aagaatataa
     5461 aatccatatg aaaataatgg ctataaatgc cattaaagct gttctcataa aaattttatt
     5521 tctcacttga gtaaagtcag gattgacttt aatattttta cttttcaatt gtataaccta
     5581 ctccccatac agtttttata aatttcgggt ttttagaagg ttcatgaatt ttttcacgta
     5641 atcgccctat atgagccata actgtgttat tattatcaag atatttttct ccccatacag
     5701 cttcaaacaa ttcttcagaa ggaaccactt ttccttgatg ttcacataaa taccaaagaa
     5761 tagaaaattc aatcggtgtt aatgctactt ctttcccaaa taaactacat ttatgtgttt
     5821 ctttattgat aatcaatcct ttaatatcat actcattaac aattatcgac tgttgttcat
     5881 aagaattatt atatcgcata tatcttctta attgtgtctt tactcttgca acaacttcca
     5941 aagggttaaa tggctttgtt atataatcat cagcacctat ggttaaaccc attatcttgt
     6001 ctatatcttc aattttagct gttaacataa tgataggata atagtatttt tctcgaattt
     6061 tctggcaaat atgaaatcca tcaatatcag gaagcataat atctaaaata gccatatcca
     6121 aatttttaga ttcaatacat tctagagctt ccttacctgt ataaaacttg tatactgtaa
     6181 aaccttcatt ttttaaatat acttcaatta aatctgctat ttctttttca tcatccacaa
     6241 tcaaaatatt ttcgttcata gattattttt cactctcctt attatcgagg tcatcattta
     6301 taatattggt aaatttacat atcaaataat tacaagcata tttgtaacta atttttataa
     6361 gaaaagaact actacatcag aatgtgttga tgctactatt ggaacacaaa aactgagatt
     6421 aattgttatt ataaaaactc ccctaacacg tccttattat cgcataacag gtattaactt
     6481 tcaataaaaa tatctatcag tcaaacacaa ttcaatttat tataccagag acaatccata
     6541 taaaaaacaa ttaaacctat gtatgtaacc acagacatta ctaaaatttc catgttattt
     6601 tatataaaaa ttcaaaaaag gagttgaatt taaaatttga ttagaaaaaa atcaattttg
     6661 agacaactcc tttttatttt aatgtattta aattatagta tatcagcctt cataatatcc
     6721 tcaaaatcac ctttttcaga tattaatctt atcaatttaa cagtacagct taaatcattt
     6781 ataagtatag ctccaactaa tgaaccatct ttcataaata attttttata tattctttga
     6841 ccttcatctt ttgatgaaat ttctttatca aaattttgta tattaccaat actaaatact
     6901 tttacattca ttgcatctaa tgaaactgga tatacttcac tttcaaatgt caaattatct
     6961 ccacttgcat ttgcccctgc tatttttccc atttctactg aagatggcca tattgctaaa
     7021 ctaatatttc ccacttgtgc aacatctcca caagcatata tatctttaac atttgtctgt
     7081 aatgtcttat ctacaacaat acctctatca atttttacag atgtatcctg aaccatttga
     7141 gtgtttgctc ttacaccaat tgaaaatact accatatcac agtcgacact atctccatct
     7201 ttaaatacaa ctttttgagc ttttccatca ccttcaatac catcaactgc tacacccaat
     7261 cttacatcta ttcctgtatc tcttacacat tgttctaata ttttactacc ttctttatca
     7321 agttgttttg atagtatgct atccatggct tcaactacta ctacttctaa tccttttagt
     7381 ctaaattccc atgcagcttc aagtcccaat aaaccgccac caatcactac aactttctta
     7441 gatttttcta gtgcttcttt tacactatat aaatctttta tatttctaag agtaaacaca
     7501 ttttctaaat catggccctt aattggtggt ataaagtttc tacttcctgt agctattaca
     7561 agcttatcaa atttaatagc tccatcattc actataatag ttttattcac ttcatctaat
     7621 ttatctacat tcgttcctaa tattactact atattatttt tatcatacca atctttatct
     7681 tccatgtaga aatctgaacc aagttcttca tttataccat cagaaagtgc aggtctatag
     7741 taagtcaact catcttcatt agaaatcata gttatcttac aagttttatt tctttttctt
     7801 atagcatctg ctgcataaaa accagctgct ccatttccta ctattacgaa atattcatca
     7861 gtatcttttc taaaagtaac ttcatcttct tcaacttcta taaattggtc ttccttagct
     7921 ccacatacag ggcatacact aggagcacta tcaccttcaa aaacttcatt acaaattaca
     7981 catttaaatt tcttagtttt ctttttactt ccaaaagtag aatttaactt atctaggaat
     8041 ttacctgtat aagaatataa tttatcaatc tcttcatttg atggtttaaa gttaacagca
     8101 aaaggtttta ctgctgtcat tctaagctga cttattctct ccatagcatt ttctatacct
     8161 tctccactcc atccatatga accaaatact gaagcaactt ttccaccatg aagaactggg
     8221 tttaacgata ttaatatatc ccatataggc tttaacgcat ctcctaatat tgttggtgtt
     8281 ccaaataata caccttgtga tactgctatt tttgccaaaa tatcttcttg cttatgctct
     8341 attacatcaa ataaatttac tttatagttg ctattttttt caatatatgc ttttatagct
     8401 tctgccataa tctttgtata tccatgtgca gaaacataac aaattgtaac ttctttttct
     8461 aactttattt gttcatttac actccagttg taataaaggt ctataatttt tctaggattt
     8521 tcagttaata ctggaccatg acctggacat acagtatcta tatctaaatc ttttatcttt
     8581 tctatagcag ttaccataga tggtttaaat ggacccatta tacaatcata atagtatctt
     8641 aaagcatcca agtaatcctt ttcttcattt tcatcaagtg tatttactat cttatcatta
     8701 ctatagtgac taccaaatga atcacatgtt acaagagttt tatcctcttt tatatatgtg
     8761 tatatggtat ctggccaatg aagcataggt acagagaaaa attctaaagt tttgtcccca
     8821 attgataatg tatctccatc tgtaactgca acatattcaa agtctttgtt tacgatttcc
     8881 ttaagatatt taattgctgt ttctgaagct actacttttg catttttagc taaatccaaa
     8941 agcttttcaa cgcttcctgc atggtctggt tcagtatgac ttacaacaat atagtctatt
     9001 ttttcaaaat ctatatttaa atcatttaat ctttcaatat aattgtcaaa atgcttatct
     9061 ttaactgtct caaataaaac tgttttttct gttcctttta atacatatga attataagta
     9121 gttccataag gtgtatacat aattatgtca aatactctta aatcagggtc aagcgaacct
     9181 acccaatata aattttcttt tatttttagt gatttcaatg acataccgta ctcctcctaa
     9241 aatagttatt tagtctcttt ataccctgct tgttatattt taaacaaaat ttattcaaaa
     9301 aagaaattat tttaaagata gtttaaatct tctaatcttc tttttctacc ttcaatacag
     9361 ttcccttttt agaatctact tttatgtcat attcattttt atctttatct attcttattt
     9421 tataaaaagt aacatctaaa tctttgtcta aactccattc tttaactatt ccattttgtt
     9481 cttttaatgc aatttccata gcttgttgag gtgtcattat gtcatttaaa tctaattttt
     9541 cttttctagc aactccattt aaatcttctg aatccaactt ttctgtttta tcttctaata
     9601 catcttttgt attagcatca attttcatct tatattcatt attatcatct acaccttcca
     9661 cagtataaac aaatttattt aaatctctct caagacttaa atctactata tcagcatcct
     9721 tatatttatc tttaaatatg tttattgcat ctgtgtatgg cactttaaaa tcttgttcca
     9781 ttaaattttc attatttttt tcatctttta aagcgttatt tgatgcattt gcctcctttt
     9841 ttgtattatc ttgtgcttgt cctgaatcct tagttggact cccactacat gcagttaata
     9901 aacccgctat aagcatactt accactaata aatacgtttt tttacacata aaaaccctcc
     9961 ttaaatatat taatttattc tatattatgc cctctaaacc ctttatttac ccttttatat
    10021 taaaaattcc tcctatttta tcaattttaa aactttatat ttactaaaat taaagttaca
    10081 taaaaattat actgtctcaa aatggaaaca agcctctttt tcattgttga aataataaaa
    10141 atatatttta tttcgtacaa aaagagtgcc tcatgaacta aaaagttcat tttgagacac
    10201 tcccattttt ttatattttt acttacaaaa taacagtact tattaatttt ttacaaacct
    10261 tataagtata tctatatgat attcttaaat ttaaacacta tattaaaaaa ttaaattttg
    10321 tttaattctt ttaccgttaa atccatttta ggatatggaa tcgtaattcc ttcttcgtca
    10381 aacctaactt taacctcttc tagtaaatca agataaattg tccaataatc ttctgtcttg
    10441 caccaaactc tagttgcaaa tttaatagca ttatctccat gttctactac tcctataaat
    10501 ggttctggtt catttattat taatttatga ttattaacaa tatctttaag tactcttcta
    10561 acatgtagta tatcatcttc ataccctaca ctaaaagtca aatcaactcg tctagtattc
    10621 tttgctgaat agtttattag actatcattt gatacagaac cattaggtat aagtatctgt
    10681 ttattatctg gagtaaccaa ttgtgtataa aaaagaccta tttgttcaac cgttcctcca
    10741 tgacctgctg cttctacgta atctcctact ttaaaaggtc taatcaatag tataataaat
    10801 cctccagcaa aatttgatag actaccttgt aaagccaaac ctattgctac ccctgctgat
    10861 gctatcacag cagcaaaact ggacaaactc attccccaat attccagaac aatgattata
    10921 acggcaactt taagtacact caaaagaaga gactttaaaa actttcttaa agttaaatca
    10981 atatctcttt tactaagtaa taacataaca tggtttacaa atttttttat tattttaaat
    11041 ccaatagaaa gtataagtat gcctattata agttttactc cgcttgtagt agcccattct
    11101 agcagacttt ccattatacc tcccatatcc atcttattaa tatctaaatt atttaaatct
    11161 aacttgctta tatcatctat tttcgtcgta tccataaaaa actccttacc ttatatttta
    11221 gaaccaatat tatagtttaa agttcttatt ttctatttaa tataatacaa taccatttgt
    11281 acatagtaaa caagatttat attccaatta tacatattag gaaaatgcaa actatttgtt
    11341 atatatatgc aaaatataat actaaattaa actattaata aaacactata tagccttaaa
    11401 atcatcattt tttaccccta tatgagatga tactatagtt ataatactta gtactataaa
    11461 tactacaaaa ccttttttat atccatcaac tatattatat gaatttactt gtaaagagat
    11521 agctataatc aaattaataa ttccacttcc tataaattca aaagtattaa taacactagt
    11581 tgccagtcca gaataaattt ctttattttt atacttggca tcattaaaaa cctgtagatg
    11641 tgacataact atacatccca taataaagaa tgatattggt aaaactataa ttggtggttt
    11701 tacctggtat acaactacaa ttacaatcca tataaacaaa tctatcattg ctccaaattt
    11761 tattatatta aatttgctag accttatttt agcaaataca aaatccataa ttattgaacc
    11821 aaatataaat ccatatgtaa aaaatgatac tataaacgca gaaaaactct tactcacacc
    11881 ataaacgtcc attatgtatc ttactcccca caagcttata aatgcacttg taagaccaac
    11941 aaaagagaac attatcattg aattatacca tgttgatttg ttctttataa cagacttaat
    12001 accatcaaca atattaacct tctctgactt ttcatagggt tcagtatcta cattgaatcc
    12061 atactctttt ggtgtatctc taacaataat atacataaaa catccaatta caacaccaat
    12121 tataccgatt aataaaaatg aatttctcca accaacaagt tcagacaaaa acacaagtgg
    12181 aaaagtagca agaactccac ctaaatttcc tacaaatgaa aatttagctg ttgcagaagc
    12241 aaattctgac ttattaaacc atctcccttg aatttttaaa atacaaagta atattactga
    12301 tgttcctgcc cctacaatta cacgagaaat atatgctaat tctatacttt gaatcaaacc
    12361 aaataaaatt gaccctaaac ttgccattat tattccaaga ctgctaattt ttcttgctcc
    12421 atatttatca atcaaaattc ctgcaggtat ttgcataaat gcatatgcat ataggcaaaa
    12481 ggatgctata tttgaaattt gtatagaatt aaaacctaac tcatttgcta aattgtctga
    12541 aacaacagca gttgacatcc ttaaaaataa tactaaaaca aatgaaaatg taattatacc
    12601 ccaaacactc cacttagcct ttgtataact tttcatatct tctccctcaa atccatatat
    12661 ttttaaattt tcttgatata acttatataa agtgtatagt tattcttaca aatttttaca
    12721 cgcaatatca ttatacaaca tatgtatata tttaactaga aataaaacac tattcatatt
    12781 atatacatga attaactaca taaataataa gagccatctt ttaacattac tcaaaagata
    12841 gctccatata aaaacattta ttctaaattt aattttttat ctaatataaa ttttgtagcg
    12901 aaaaataacg ctattgcaac tacaagacta ccaagtattg caagcataaa actaggactc
    12961 tgataaagat gatataccat atttgtatct tcatttggta agatgcttcc aactgcatct
    13021 ccaacaattg atattactat atttatagct ataaaagaag caaatgccac tatgtttcta
    13081 tgtttattga attttggcaa ttgtcccatt gagattgatg tatataataa caaaataaat
    13141 gatgaatatg aaataaacat tactactact aataataaaa tatctaaaaa gttttcagaa
    13201 atccatttaa aactagtgtt aaacaaatct aaaatttcag gtagtaaaat tccagaagta
    13261 ccaaaaagca taagaactcc aaaagtgaat actgcaacta taaaactaag tacagcgtat
    13321 ataagtgctg ttatacattt agataatata agtgaactag tgctaacagg aagagtaaac
    13381 attaaataac cttcatcccc caaaagattt tttctaaacc tttgaattgt aactacaata
    13441 gttaaaactc ctaatgccat aaaaagactt gttaatacta gtattcctat tccctgtacc
    13501 tgaagtatat ttgtattcat aaatattcca ttaaatacag ctactatcaa tatggctata
    13561 tataacggta taaatattct tccacttgct tttaactcat attttaataa tttacctaac
    13621 atttaaattc ctccctaaat aatgcatcta tagattttcc tttttcttct cttattgctt
    13681 caacgtctcc ttgtaacact atttctcctt ttgatatgaa tattatctca tcacatatgt
    13741 tttctatttc acttattaag tgggtagcaa tcagtaaagt actatcttca gaataatttt
    13801 ttaatatagt cttaagtata tatgaccttg cagctgggtc aacaccacct ataggttcat
    13861 ccaatatata tatgctcgca tttcttgaca ttactaaaat aagttgaact ttttctttag
    13921 ttcctttaga cattgtcttt agcttttcat ttacatcaat atctaagctt ttaatcatct
    13981 catttgctct tctaacatca aaatcactat aaaaatcata gaaaaactta agtaaatctg
    14041 ataccttcat ccaatcattt aaataagttc tttctggtaa atatgaaact atttttttag
    14101 tatctatgga tggtttcatt ccatttatca taatttcacc attatcaggc tgtaataatc
    14161 cattcattag cttaatcatt gtacttttgc cacttccatt aggtcctaac agcccgacta
    14221 tttttccctt tggtatattt aaatcaatat tttttaaaac attcttagtt ccataactct
    14281 tgtttacacc tttaaattca actattccat cttgagaaac attgcttata tttttatcca
    14341 ttttataatt ctcctttcag attttctgta ataagtttta gcatttcatc tctatcatat
    14401 ccaagctttt ctaaggttac ttttaatgta tttatctcca cattagctat ttcctctttc
    14461 atagctttta ttttttcctt atcatctgtt acaaatcttc ctttagttct ctgactataa
    14521 actaaacctt gtctttcaag ttctgttaga gccttttgca ttgtatttgg attaacttcc
    14581 gcatcttctg ctagtgctct cactgtttct aatttagatc ctattttaat ttcccctgaa
    14641 attattttta actttaaatg ttctactaat tgtatatata taggtttgtt attatcaagt
    14701 tcccattcca tgttcatgcc tccttattat attatcgtat taagttgtta atacaataat
    14761 ataataatac aaagtatatg tcaattactt tttagtaaaa gtataaaaaa ttttacaaaa
    14821 aaaatgaaca ctacattaga gtccattttt aacacaattt attaaattct ttatattaca
    14881 gattaattac cctcttacca agttagatac aattaaatgt tcaaattctt caattggcat
    14941 tggctttcca aacaaatatc cttgtgccat atcacacttt acttctttta aaagtttaaa
    15001 ctgttcttct gtctcaactc cttctgatat gactttcata cccaactctt ttgccatttc
    15061 tattacttta gtaacaatta ttttgcttct tttactatta taagtttcca taataaattt
    15121 ttggtcaagt tttaagatat ccataggaat ttcttttaac atatttaatg atgagtaccc
    15181 tgaaccaaaa tcatccatag atattaaaaa tcctattttt tttaaattat tcattatatc
    15241 aattaaaata tcaaaattat caaatatgat actctccgtt aattcaagtt ctatatactt
    15301 tgcaggtata ttgtatttat caattatatt tttgtatgtt tctataaaat tattgcaata
    15361 taaatgtatc cttgaaacat taactgaaac agtaactgga tttattcctg catcaatcca
    15421 ttttctaagg tatatacata cttcttcaag cacatataaa tctaaattta taacaaaacc
    15481 gtttctttca aaaaatggga taaattcatt tggaggtatt agccctttat caggacgttt
    15541 ccacctaaca agtgcttctg aaccttgtat ctctcctgta ttaagttcta tcttaggttg
    15601 taagtatata ataaattctt tattttctag acttgaaaac attgtatttt ccatctcttt
    15661 ttcttttatc tcttggtcat gaatcttatt atcataaaat gcatatgaac ttttatgtcc
    15721 tccctttgcc attttatgag gtatattagc cctatctatg attgagttga tatctctatc
    15781 ttctggaagt ataaaataga ttccacaact taaaactaac ttatattttt cttcttgatt
    15841 attattaaac aagtctaatt cttcaaatat agtttttaac ctctttgtta tatcttcttc
    15901 ttctatatat ttcataatta taataaaatt atccgcagat attcttgcaa acatttcctc
    15961 ttcaaatata ttgctcttaa taatctttgt taaattacgc aaaatttcat tcccaacttc
    16021 atatccaaat aaatcattta tatatttaaa tttatcaata tctatatata ataaagcata
    16081 ctttacttga gtatttttac atagtatttt gttagcatca attacaaatt tatctatagt
    16141 atttgctcct gtaagattat ctgtatatgc tatcctttgc aatttaattt taaaatttaa
    16201 tttatcatat attatataga atataagtat tacacatatt atagccataa taagtattat
    16261 ttgtattgca tgtttgctaa taagctgatt attagacaca atagactcaa agttatttat
    16321 ggagttgttt ttatagagtt tgcataaaga atagactggt gttgtgtatg taatttgtaa
    16381 aattatacaa ataaataaaa aaaacatcaa ttttttttgt aaattcctca taaaaatttc
    16441 ctcccattaa aacacctcta ttttattagc aaataagtac atctcaaaag tttccatttc
    16501 ttgtaaaatg gatagtttat atctacttta attttgtaaa attttctgct actataatta
    16561 tagaatgtag catattcatt gtcttaacta ttgatttata tatttcatat aggtataata
    16621 gaaaataaat tggattattt tggcatataa ttatttatta aaaggtgatt atttttgttt
    16681 aaattgtctg aaaaatttta tttttatatt ataattttaa tattttcttt tcaaaactat
    16741 ccattttaca agaaatgact actttttatt aaaatacagt atttgcaaca tattcacact
    16801 ttattttttc atttttttct tattacaatg gtttcgacaa atcagtaatt aatttttata
    16861 aatgaataaa tcaaataatt cctaaattaa tttttttagt atctcacttt caacttgatt
    16921 atttaaatat aaatttct
//
LOCUS       DAGQVA010000086        16869 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.086, whole genome shotgun sequence.
ACCESSION   DAGQVA010000086 DAGQVA010000000
VERSION     DAGQVA010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.086"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..357
                     /locus_tag="MIV85_003140"
     CDS             <1..357
                     /locus_tag="MIV85_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBY2962462.1"
                     /translation="ILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGY
                     SCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVK
                     SSLPAFEKLAKLYNLK"
     gene            527..1489
                     /locus_tag="MIV85_003141"
     CDS             527..1489
                     /locus_tag="MIV85_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBY2962463.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(1611..2273)
                     /gene="zmp1"
                     /locus_tag="MIV85_003142"
     CDS             complement(1611..2273)
                     /gene="zmp1"
                     /locus_tag="MIV85_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBY2962464.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(2373..2458)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2644..5562)
                     /locus_tag="MIV85_003143"
     CDS             complement(2644..5562)
                     /locus_tag="MIV85_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBY2962465.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      complement(5680..5765)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(5892..7070)
                     /locus_tag="MIV85_003144"
     CDS             complement(5892..7070)
                     /locus_tag="MIV85_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBY2962466.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            7445..7630
                     /locus_tag="MIV85_003145"
     CDS             7445..7630
                     /locus_tag="MIV85_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBY2962467.1"
                     /translation="MFFISYIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            complement(7695..10469)
                     /locus_tag="MIV85_003146"
     CDS             complement(7695..10469)
                     /locus_tag="MIV85_003146"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBY2962468.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(10641..11897)
                     /locus_tag="MIV85_003147"
     CDS             complement(10641..11897)
                     /locus_tag="MIV85_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBY2962469.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSTVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(11969..13471)
                     /locus_tag="MIV85_003148"
     CDS             complement(11969..13471)
                     /locus_tag="MIV85_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBY2962470.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(13562..14752)
                     /locus_tag="MIV85_003149"
     CDS             complement(13562..14752)
                     /locus_tag="MIV85_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2962471.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            complement(14991..16079)
                     /locus_tag="MIV85_003150"
     CDS             complement(14991..16079)
                     /locus_tag="MIV85_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962472.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            complement(16364..>16869)
                     /locus_tag="MIV85_003151"
     CDS             complement(16364..>16869)
                     /locus_tag="MIV85_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBY2962473.1"
                     /translation="VIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDILLKPLDM
                     KEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSNISRIFKS
                     NLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIEKGMTPKV
                     YKLNTKN"
BASE COUNT         5303 a         2938 c         1972 g         6656 t
ORIGIN      
        1 atacttggat ttgtaaatgc tccttctctt tttcaaaggg ttattgcaag aagtttagat
       61 gcagaagttg atgtaaatat ttataaaaag aattttgacc ttctatataa tagtttaatc
      121 gatatgggat attcttgtgt taaacctaat ggtacattct atttgttccc aaaagctcca
      181 attgaagatg ataaaaaatt ctgcaatgat gcaaaacaat ttaatttatt attagtacca
      241 ggttcttctt ttggttgtcc aggtcatttt agagtatcat attgtgtatc ttatgataaa
      301 gttaaaagtt ctttaccagc atttgaaaaa ttagccaaat tatataattt aaaataacta
      361 aatcaaagta attcaaataa ttaactacct tagtatagaa tacttacatt ctatattaag
      421 gtagtttata attttatgta ctatatttta tacataccat attattccaa tatgcttgaa
      481 tattcttatc tatagtacta atataaatta caaggaggtg tttgacttga aaaaaggtta
      541 tgtttatata atactgacta ccttattttt tagttcaatg gaaattagtc taaaaactgt
      601 cactaatgac tttaatccct tacaaataac tttatcaaga ttttttgttg gcggtttagt
      661 cttactacct tttgctgtaa aaagattaag agctcttagt ctttctatta caaaatcaga
      721 cttaaaatac tttgcatttt taggttttat gtgtgtagta gtaagtatgt cattgtatca
      781 acttgctgtt ctaaacacaa aggcatctgt agttgctgtt ttgttcagtt gtaatccagt
      841 ctttgtaatg cttttagctt acttaatttt gaaggaaaaa atatataggc acaatgtaat
      901 ttcacttata ttagaagttc ttggaattat agttataata aatccattgc atacaaaact
      961 aactcttagt ggaatattct taacattatc ttctgctatt attttttcaa tgtatactgt
     1021 atttggtaaa agaaaaacct taaaatttgg tggaatagtt gtaacctgct ttagctttat
     1081 atttggtagt ttggaaatgt tgatattggt tttactcact aaaattaatt ttatcgcaga
     1141 tatattaaat aaaaataagc ttcatgtatt tgcaaatatc cctattttta gtggatatac
     1201 cttacacaat atgcccatta tgatttatgt attcgtattt gttacaggtg ttggttatgc
     1261 gctttacttt atggcaatgg aagctacatc tactagtctt acatctttag tattcttctt
     1321 taaaccagta atatctccaa tactagcatt attaatactt aaagaaatta tccctataaa
     1381 catggttata ggaattttat tgatagtaat tggttcaata atttctatta tacctacgat
     1441 aattactcaa atgcataata aacacgttga agccttgtat aaggagtagt aattgataat
     1501 ctatcatagt tatacataag acaaaattta ttagatttaa acgcaatata aaagagatgc
     1561 tattataata gcatctcttt atttatattt attttaaatt tattaaaact ctatttagct
     1621 aaattttgca aaaagctata agtttgtgga caagctgatt ttaacttact atttgtatct
     1681 tgatttaaat agtaatatgc aaatgattct gcaaaaaatt cttctggata tacacctaag
     1741 tagtttacat tacctaaaga acgaccttct ttagcaaata tttgtttgaa ttgtgctgat
     1801 ttagatatat catttaatac tatatggtct attgcatgtg ctgtttcatg taattctaaa
     1861 tttattgcat catgcccttt acctttgtta ctaaatccta ttctaagagc tactgtactt
     1921 ccacctaaac ctggaacatc atcccaagtt tttccagtac cttcccatcc cttaggaact
     1981 acacctttta aataagcata ttctttttca tctgttaact ttccacttaa taattttatt
     2041 tttaagttat tttgctttaa tgcatttaaa tactttccat ctatattagc taatctattt
     2101 accatagcat tagcttcgtt tttatcgtaa tttccagttg gaaaaactac tatttgacta
     2161 agtgtgtctt tattttgttg tatagtagta ctatctgcat gtgcacttac tggaactgaa
     2221 cttattaaga atattgatat tatagctatt aataattttt tacttggtct catattattc
     2281 cctcctttga gttaggccgg gagtaataaa tttcaaaata aaaaagatac ccaagagtat
     2341 ctttgtatat acaaaaagaa atttttactc ttttcggcaa ctggctggca tggtttacta
     2401 aactttagcc cctatagctt tgcgtgacta ggtttcccta gttttgcctc atttaatttt
     2461 atatctatat tatagcttat atctttttaa ttgtctatat ccctttggaa cttttttcta
     2521 aaaagttatt atttttttac ataaatcttc aaaaaaaaat atcttctaac aatattttca
     2581 ttattaaata ttgttttaga agatattttt taatataact tatatttttt ataatgttag
     2641 ggtctaattt gtatttttat ttcttcttaa tacgataagt cctacaatag ctcctataac
     2701 caaaagtatt tctccaataa ttgtagtact atcccctgtt tttggtggta ctggtggatt
     2761 taccaaagta tcatctttaa ctttattatt tttttcttct gacactgatg gctttactac
     2821 ttctggtatt ggaataatct gtttaacagg agtttctatc atctcttctg atggtggtac
     2881 tggcggattc aatacctctg gtattggcgg atttattata tcttctgatg gtggtattgg
     2941 tggatttata actatagtat cctctgtatc agatgaactt gatggtttcc ttggtttatc
     3001 tgtgcttggt ggtactggtg gatttactat tggttcatct gtatttggtg gtgctggtgg
     3061 atttactggt ggattttctt gtcttatgtt ttctatattt ccaatatcca ctattctacc
     3121 aatatcttta ttaccaattt caaccttaat tttatccttc agtttttcat atccacttgg
     3181 agccattatc tccactaaat aatatgttcc tggttttttt atactagatt gaattatacc
     3241 atcttcatca ctaactaaat ccttaactac tatatttcca aatgcatctt ctaaattgaa
     3301 cttagcacct gaaagtacat ttttatctaa agcatccact tttttagctt caaaagcata
     3361 accttgctta gtagtctcta ctcctggagg acttgaacca ttaatctgag ccacattttg
     3421 tatagtctcc ccaactttta catttgtgaa gtctgcatca aatgtaaccc aactttgcac
     3481 aggttcccct tcttttatct gtttaaattc gtatttattt actaatctta ttgtattttt
     3541 tccatctcca gcttcttttt taagttcaag attatcagaa tattttatat tagatatttc
     3601 tagagctgag tttacttcat ctaaaagatt tacttgtcct gcatcataaa ctccataagt
     3661 tgacatattg attttgtatt taacaatctg gttatcacta ctatttaaaa cttttttatc
     3721 aacttctttt tttgcgctta ttaatccaga atttttctta aagtttatct catcattttt
     3781 atcaatttca ctattatttg catcaagaac agctctattt atatagctat cttcaatact
     3841 aattaccttt aatgtataag ctataaaaaa ctttgattcc acttcttctt tactgagatt
     3901 aattgtaaat ccagttataa ctttatctac ttgcccactt tcatttcttt tttcttctac
     3961 tttatatgaa atattattgg caattttttc tttactccaa ggagtccagc tcccattcat
     4021 tggaatttct acaactctaa aatcatgccc agcttctcct gaagtagtta atctcatgcc
     4081 ttctggtata ttatctgtta taacaacatt acttattggt gatttatcat catttattga
     4141 aatctgatag tttattactt gaccaacttg agtaatattt gttgctcctg aatgtccttt
     4201 agtaagaaga taatcatctc ctctatcaaa tatacttaca gtagcatcat cttcttgtat
     4261 cttcttacca tcagattcaa tcctagctac attcttatat ttattaccat gttttgcgtt
     4321 tttgtcactg attctagcct tatacttaac agtatacgat ttatctatat ttccaaaatt
     4381 aactgaaata gaatttttac tctgttcaat attaaaatca ctaacttctt ttccatcact
     4441 tgttactaca cttacagaac catttatcaa tgtcaatcct tcaggaagct catcatacaa
     4501 aataatatct tttaactctt cctgcttttc atttacttgt atactgtaat ttatatcttt
     4561 atttttaact ggcataaata cagtagttga tttttttcct tcaacaagct ttttaagtgt
     4621 tcctttagca tctggaacat ccgttttatc tccaggtttt atttctacat ctatatctcc
     4681 acttccactt tctatttttc cagtagtttc aatatgtatt tttgcattag tatcttcatc
     4741 aaccttttta acatatgctt ccaaacctat tttaccttgc attacacttt ggccattagg
     4801 taattctcta aatgtaagtg tatactctcc attactttct gttttatcaa agcattcact
     4861 tgtataatct aaattaactt tattgaatac atctggcacc ttaaaagtta ttgaatctcc
     4921 tgcttgtatt ccttttgatg ttggagtata agttaaatta aatgatattt ttttcattga
     4981 ttccgtttct attgtattgt tattaatttt tacaacaaat ccatagtctt cattttcttc
     5041 attaagttct tcttctaaaa ctttcaataa attttcatct tctaatagat tatcttcctc
     5101 tggagttttt tctgtatttt tattgtctag tggtttttca tcttctaaag cttgttctga
     5161 ctttttatta tctgttgact tatcttcttc tggtatctgc tctggctttt tattatctat
     5221 tggcttttct ccttctggag tttgctctgg ctttttatta tctgttgact tatcttcttc
     5281 tggggtctgt tctggttttt tattatctgt tggtttttct tcctctgggg tctgttctgg
     5341 ttttttatta tctgttgcct tatctttctc tggagtctgt tctggctttt tattgtcgct
     5401 ttccttctcc tctccagttg atgaattagt tgaaccactt tgaatctgac tattctctcc
     5461 taattctgaa gcataagata cagttggata tattgtagac accaccatac ttaaaatcat
     5521 aattaaacta attaataatg cctttctatt tcctttcttc atgtaaatct caccccttta
     5581 ggttacctat aatttataat ctaatcttcc attaatatcg tatataaagt aatttttact
     5641 aaaaaattat acaaaaaaag ctatgaaaat aaataaattt atattcatag ccggttgcac
     5701 cactgactca gtatatccat aaggtgccca ataatagaat atacttcaac atctctataa
     5761 tatttcataa aaacaattaa aattgcttta tttatattaa aaatacaatt atatacttct
     5821 attatattat gcctctatac tattgtctat cctttttaca ttttttacct tatgatgaga
     5881 ttaattaata attaaataaa atccttatct acaacaatta cacaattata ttcaggattt
     5941 atctccttaa ctaattttgt tatatcttct tttaagtcat cttctgacat gtttttggaa
     6001 aattcggaag gattaactac tatatcaaat attaaattct tcttgcttcc ttttccaact
     6061 attctaaaat catgcataga ttttacaaga ctatttttct taagtatttc ttcaagttct
     6121 tttttggctg acataacttc tttatcttca agacatattg ggtccatgtg aattactaga
     6181 tatatatcta atttttcaga tatttctctc tctgcagtat ctataatttc atgtatttcc
     6241 attatatcta tgttggatgg aatttctgca tgtatagatg caatacatct accaactcca
     6301 tagttatgaa taattaaatc atgtgtacct attatatatt tataagataa caatagctct
     6361 ataatagaat ttaccatttc ttcatctggt gcttccccta aaagaggatt tatagtatct
     6421 tttacaagag agaaaccagc ataaagtatc actaatgata ctacgatacc aacatatcca
     6481 tctataggaa aattagtaaa tctagctaca ataaatgata taactacaca gcttgaagta
     6541 aatacatctc ctaaagcatc aagtgaaact gcttttaagg ctgaagaatc aattttattt
     6601 cccataaatt tattaaaacg actcaaccag attttaatca ttatagatgc aattaaaagt
     6661 ataagtggta ttacttcaaa ttttacagga attggattta ctatcctttc tatagatgac
     6721 tttacaaatt gaagtccaac caacatcacc ataaatgcta ctattaatgc tgataaatac
     6781 tctattcttc catgaccaaa agggtgttct ttatcagctg gcttacttgc taatttaaaa
     6841 cctatcatag ttattgctga agatgccata tcagaaagat tattaaatgc atcagccatt
     6901 atagctatac tagatgtgag cattcctatg aataccttta tcacaaataa aagtaaattg
     6961 gataatatac ctactacacc agctacataa ccatacttat ttctaacatc tgtattttga
     7021 acgttttcgc tatctctgat aaatgttttg actaggattt tggaaaacat gaaacttacc
     7081 tccctgccct ttattttatt aacaaatttt ataatctata tctttattta tgataacata
     7141 atttatatat aaaattctta aaaatcactc tacttcagta aaatattatt ctatatatct
     7201 atttagatac gaattttata tttagtaaag tttttatggc ttagtgtctg tttaatagat
     7261 tctatataag tttttacaaa gattatttat tatgataata tcatttttcc caagtattac
     7321 ttagaatatg atttttttgt tttgtctgta catattttaa atttatacta tatttatcta
     7381 tattttataa ccttatgata cactataact ataagttttt aaatggaaag gaatgaaata
     7441 aatcatgttt tttatcagtt atatttacac aaaatcacct attaaatttg atactccttt
     7501 gcaaaaagag gcatataaaa tattacaaaa attagatatt gactttgaat gtgttgacac
     7561 agatgaagca attacaatgg aagattgtgt tcagattaat aaaaaattaa atatgaaaat
     7621 ggtaatataa aacaacatta aacaaacaaa aaccgcaaag ttacaatata tagtacttta
     7681 cggtttcata agaattaatt tttactatta aagttcatag ttctactatt tttcattgtt
     7741 ctaagaatta gctttacaaa ttcatttgac aataggatag tggatgcaaa tagtattatc
     7801 tttatccaca tatcaaagtc caaagaaaca gaattaaaga aactttggaa cacttgtgta
     7861 aatattattt gaattatccc tgtaactact attatttgca atgccagttt atttttaaag
     7921 aaatttggta ttgtactatt taaaccaaac tctctacaat ttaatgcatt aaaaagggca
     7981 ctgaatgcaa ataaagaaaa tataacagta ccttgttctt ctgatgtagc tcccaatata
     8041 ttaaaagctg attgagtaaa tacaattgta attataagaa ttgcatttat aataatattt
     8101 acaaacatag acctagctat tattccagaa tgtctattta ttggttttct tttcaataca
     8161 taatctctaa caggttctaa tcctaatgct agggctggag gaccatccat tattatattt
     8221 acccataata attgtattgt agtaaatggc atatccttac cagtaagttg agatattata
     8281 gcaattataa atgctactat atttacagta agctgaaact gtataaatct ttgaaagttc
     8341 tcatatatac ctcttcccca ttttattccc tctactatag tactaaagct atcatcagtc
     8401 aatattatat ctgctgcatt tttagatact tctgttcctg aaatacccat tgcaattcca
     8461 acatctgctt gactaagtgc tggggcatca tttataccat cacctgttac agctacaact
     8521 tcgccacttt tttgaagtgc tgaaactatt ctcatttttg tatctggttt acttcttgca
     8581 acaatagata ttcctttgat ttcttctctc aattctttat ctgtcaatac atctatatat
     8641 gttgcttcaa ctgccttttt cccatcattt aataatccta attcatttcc aatagctgtt
     8701 gctgtattta tattatctcc tgtaagcatt tttacatcta ctcctgcatt aaatgcttta
     8761 tcaatggaat ctttgacccc ttctctcaat gggtccacta ttcctacaaa tccactaaaa
     8821 actaaattat cttccttcat ataacttctt gaatttccta ttaaattcaa ttcaccttct
     8881 gaagtcattg caacttctgt tttagaatta ctcatttttt tataagcaaa tcctaatgtt
     8941 ctcatagatt taatttgtaa cttcttaatc tcatctaaaa tacttttttc tacttttgga
     9001 gttattggaa caatattttt tccttgttgt acataagaac atttttttaa taatacttct
     9061 ggagcacctt ttgaaagtaa tatatctgaa tcctcttgac gaattaatgt tgacatcttc
     9121 ttttcttctg aactaaatgg tatttgtgat atcaaatacg tttgttttct catttcatta
     9181 tagttcttat cattatgata taaaagtaat gcacactctg ttgcgcttcc tatatattta
     9241 aatgaattat cttctttttc tatatctgca gttgaattta ctatacagtt ttgttcaaaa
     9301 tagctattac tttgatactc tcctccactt atatatttac catcaacata tgctacctct
     9361 accatcattt tgttttgtgt taaagtccct gttttgtcgg aacatattac agaaacagaa
     9421 cctatagttt cacaggcttc tttctttgtt actaatgcat ttatctttgc catcttttgc
     9481 attgttatag ctaaggtaat atttatcata gttggcaaac cttctggaac agttgcaact
     9541 attaatgcaa tacaaaccat atatgcattt ttagcaggtt ctaatgattg taagaaagat
     9601 aatatactgc ttgtatctaa aattaacata ccttttctct gcatctgtat aatcataaac
     9661 atacacaata aagtagctat tatgcctgat attcctgcta ttttagcacc caacttccct
     9721 aatttaattt gaagtggagt ttgctggtct tcatttgata aattctgtgc tatcttaccc
     9781 atctctgtct tatcaccagt atgagtgaca accattatgc ccctaccata tgctacaaga
     9841 gtccctccaa ataccatatt gacttgcttt gcaggtattg catcctgttc gattatttct
     9901 gttttagaat aaactacttc catatctaat acagcatcag cattcttagc tacatcatca
     9961 gattctcctg ttagcatatc ttctctaagt ttcaaattta tagactgtat aagtcttcca
    10021 tctgctggta tcatatcccc agtttctata tatacaatat ctcctggtac taaatcattt
    10081 tttgatattt taattatctt cccatttcta agcaccttta cttctatatt ttctgttaat
    10141 tttgacaggg catgagctgc ttttttagat tttccttcag ttattatgcc tatagaaatt
    10201 ccaataaaaa tagcccctaa aatacctaat gcgtcatgta attctcccac aaaagaactt
    10261 attactgctg ctcctatgag aattaatatc ataggttctg tcaaactttc tcccaactcg
    10321 tcccaaaatg ttctaccttc ttttatagta aattcattta atccatatct aagcttcctt
    10381 tcttctacct cattatcatc aagtccaatt tctggatttg tttttaagta ttttaatact
    10441 tctttggtag gtttattata atacctcata actttatccc ccttgttaat tatctataag
    10501 gaattatatg cttatgatag cttgtatatt acttttcaaa aaaaataagg tgttgattaa
    10561 tcaacacctt atagtggtta tatattatta aattttatgt tacaggcttt ataaattgtg
    10621 agctatacaa atcaaaatat ttaatcttca aaataccctt ctggatataa tggaaactta
    10681 gatataagtt cttgtgcctc tgctttacat tcatctaata cttctttatt atcaatattt
    10741 tctgctacct tattcattat ccctgctatc tgtataactt ctttttcttt cagacctctt
    10801 tgagatattg atgtaagacc tatacgaaca ccactagtta caaatggtga ttgtgggtcg
    10861 tcaggtataa catttttatt aactgttatt cctacatatt caagagcttt ttcaaattgt
    10921 tttcctgtaa gattcttact tcttaagtca accattacta tatgattatc agtacctcca
    10981 cttacaatac taaaaccatg tgaaatcagt tcagaagcta gagtctgagc atttactaca
    11041 acttgctcca ttatcttttt aaatttatct gtacttaaat ataatagtga aaaggctttt
    11101 gctgcaactg tattaagatg tatagaacct aatgttcctg gaaaaacacc tttatcgagt
    11161 ttctttgcat gttctgcttt acaaagtaca ataccacttc ttggtccaca gaaagtcttt
    11221 gtcgtagatg aagaaacaaa atctgcataa ggtacaggac taggtattac tttcgctgcg
    11281 actaatcctg caacatgtgc catatctacc ataaagtaag ctcctacttc ttttgcaacc
    11341 tttgatattc tttcataatc tattaatctt ggatatgaac ttgcccctgc aattataagt
    11401 tttggtctac attcttttgc ctttgcttca agagcatcat aatctatacg tccagtattt
    11461 gggtctaccc cataaaattc atatttataa atgtcatgta aaaaattaac tgtgctacca
    11521 tgtgtcaagt gtccaccttg gtcaagacgc atacttaaaa cagtgtcatt tggttttaat
    11581 attgatgaat atacacaata gttagctgta gaacctgaat acggttgtac gtttacatgt
    11641 tctgctccaa atacttcttt tgcacgtttt attgctaggg tttcaagttt atctgcttct
    11701 tcagaacctg cttgaaaacg agcccctgga tagccttctt ctgttttatt tgtaaataca
    11761 catccactta attcaagtac ttctgttggt gctgtacttt cagaagctat catctcaata
    11821 ttgtgttctt gtctaaccaa ctcatcagct acaatcttgt ataactctgg gtctgaaatt
    11881 tttgttgttt ttaacataat aatcctcctc ttaattaaag aatatatttt attagtttaa
    11941 tcttcattga taaatttatt ataacggtct ataaaacgta agatattcct ccaccaggtc
    12001 ctaatggtat gccaataccc atgaatagta acaatattat tatttctatt aatgtaaata
    12061 ccactgagta tggaatcata ttcgatatga cagtacctat acctatatct ttatcatatc
    12121 ttctggcaaa ggccaaaata actggaaaat acggaaaaag tggacttatt ggatttgttg
    12181 aagcatctcc aatacgataa gctatttgag ttaatgctgg attaaagtct agtagcataa
    12241 acatgggaac aaatataggt gctaaaatcg cccattttgc agaagcactt cctacaaata
    12301 aattgataaa tccagatagc aatataaatc ctattatcaa tccatagcta ggtatccccg
    12361 actctgctag taattttgct cctgttattg ataaaattgt tcctaagtta ctaagattaa
    12421 ataaattaat aaactgggat gctataaatg ctaggactat atatccaccc atatcactca
    12481 tactactacc catcatagat actaaatctt tgtcactttt tatcttctta cttacttttc
    12541 catacactaa tcctggagtt aaaaatataa tagtgattat aggaactata cctttcatta
    12601 aaggtgcatt actagatagt atagaaccag tctctggatc tttcataaat gcattgtcac
    12661 ctatacataa ggcaactatc actactacta caactaacaa tgataataaa gcgtatttta
    12721 tacccttatt ttcaagttca ctcaattcct gtatatcctt atcatttgtt gaatcattat
    12781 attttgtaaa acgaggagct ataaattttt cagttacaaa tgctcctgca aaagttaaaa
    12841 ctatcgctga tataaaagca aaataaagat tcattgctgg attgccttgg taagatgggt
    12901 ccatcatttg agctgctggt attgtaaatc cagctaacaa tacatctgta gtactaagca
    12961 taacatttgc tgcaaatccc cctgcaacac ctgcaaaagc tgcaaacata cctacaagag
    13021 gatgtcttcc aattcctaaa aacacaagtg ctgcaagtgg tggtaatatt ataaatccta
    13081 catctgctgc tgtatgtgat aacatacctg caaatacgat tgctacagtt acaagttttt
    13141 gtggaacttt acttataccc tttttcatta acacttccat aaatccagat ttctcagcaa
    13201 cacctgctcc aagcattgta accagtacta atcctaaagg agcaaatgac tgaaagtttg
    13261 taactatgct acctaaatat gattgaatct gctctttctc tagtagattt actaccttta
    13321 caacttcttt tgtagaagga tgtatttctt ctactcctaa attagatata actgctgaca
    13381 atattacaac aattatacat agtaataaaa atatggttac tgggtctgga agtttatttc
    13441 ctgctctctc tacaacattt agtgccctca tcaataatcc actatctttg tttttttcct
    13501 gtgaattaat tttcctcaaa ctaatacccc ctcataaact ttatctccag aatgctctat
    13561 cttaaatttt attttttaat ttatccatat aatttataac agactgacat agtacatttg
    13621 tacctactaa tatagaattt ttatcagctt taaatttagg attatgccac tgatatatac
    13681 aatcttgttc tttgttgcct acccctaacc agtaaaaaaa tcctggggct ttttccatga
    13741 atatagaaaa atcttcccct cctgtagaag gtattggatc aactatagca tcttctgaat
    13801 acaaatcaca cacagactta caagctattg cgtacatctc tttactattt ataacagctg
    13861 gtaaatcaaa taaataatct agctttgcag ttgcttgata tccacgagct atctcacaaa
    13921 ctatattttc taaattttct gatattttct ttcgtacttc attactaaag cttctacatg
    13981 tgcctgtcat atctaccttt tctgaaatta cattatttgc agtccctcca tttatagtac
    14041 ctattgatat aacagctgat tctaatggac ttatgtttct gcttactatg gtttgaatac
    14101 ccattataat tgcacttgat gctactatag ggtctattgt tctgttgggt atacctccgt
    14161 gacctccaaa tccatttact tctatcttaa tagtgtctac tgctgccatt aacccaccta
    14221 acttaacacc tatttttcca caaggtatat ctggatgatt atgaagtcca aatatagcat
    14281 caacttttgg attttccatt actcctcgtt ccactaacat cttcgcacct ttattgactt
    14341 cttcggctgg ttgaaatata aactttacat ttccatgaag actatctcta atatgagaca
    14401 atacatatgc acatcctaca aggcaagatg tgtgtatatc atgcccacat gcatgcatta
    14461 taccatcata tctggattta tacttaatat caacctcttc atatattggc aatgcatcaa
    14521 tatctcctct tagtgctact gtgggaccat catacttccc ttttaataat ccaacaactc
    14581 ctgtttccat tcctaaatct aatatttcta tgtctaaact cactaataaa tcttttatag
    14641 cttttgtagt cctaaattct ttaaaactta attcggggtg catatgaata tctgtaaaaa
    14701 aatctaaaat atcttcttta tacttttctg agattaaaat aagttcatgc atactaacac
    14761 ctctccaaaa ttttattttt ttatttttta taatttaact acaaattata taagttaata
    14821 atctttataa agatattttt tataaattta attttagttt atatttatat tttactatat
    14881 tattttaatt aaatatatta tcatgttttg caatttattt aactattttg actttttaaa
    14941 ttcggattat ataaaaaatt tctttaaata aaaactatta ataagtggct ctattcctga
    15001 ctttgtgttg atttttttct acatgtaatt gctttataca ccatacagac taaaattaaa
    15061 agccccatat aacctgtata tggatataaa atgtttacta atttaccaaa tggtaaaaaa
    15121 cctcctatac aagccaaaat agctattact gttgttacca atttaaattt aggatgttca
    15181 tcttcaacaa ttctattggt tacagaccat aaaagtggaa cagctgttgt atagatacct
    15241 aatattaatg caactgaaaa acatacacct acaataggag atatattatc tgctaaataa
    15301 agtgatggta tttctttcat atacaaattt cctatatctg aaatcatagc caaatacata
    15361 actataccag cagtcataaa cactattcca cctaataagc ctccccaaaa agcatccttt
    15421 ttactttcaa tagaagctcc cattcctgtt aaaaaaacaa tcattacaat aatatttaat
    15481 gtattatata ttacaccaga aacgattgga ctttctgatg cttttgtaac ttcaatattt
    15541 ttcatagctt ctccaaccat agataaacca tcaaaatgct taaacaagct tattaatcca
    15601 acagcaattg taaatactgc tatcactggt ccaatacgtc caagtatgct tactaatttt
    15661 tctaaaccca tagacactgt aattaaagta gcaacagcca tcaatactct tcctaagtaa
    15721 ggatttatac catagtattc agttaaagtt gagcctgcac ctgaaatcat tactataaga
    15781 atcccaaata aaaatattgg actaaaccat tcgtaaaatt ttcctaaaat cttcccacaa
    15841 taaaaagtgt aaattcttgt tggttcttta agttttaatt ctctacctct agttataact
    15901 tcagcaccaa gaaatgaaaa caataccatt gatattaatg ctccaattaa acccatatac
    15961 ccttgtgagg caaaaaattg tagaatttct tgaccagtag caaacccaga accaattgct
    16021 gttgctagat aagcgcctgc aatacagata atatttttca tattcacttt gtctgacata
    16081 ttaaattacc tccattataa agttaccttc ctttaagaaa tataaactct cagtgaatta
    16141 aatgaaaatt ctgtattttt aaaacagtat ttaattcact ttttttattt tgtatatctt
    16201 tttcttttta tttatatata tttttttata taaataggta cagcttttat aaggtttaat
    16261 attattaaat atgtttaaag cgctttaatt tttatcataa ttaaagtata cttattcaga
    16321 cacactcaaa caattatcta tattgacttt ttatttatca atttcaattt ttagtgttca
    16381 gtttataaac ttttggagtc attccttttt ctatcttaaa gtttttataa aagttattta
    16441 ggctattata tccaactatt tctgcaatct catttatact ttttgtagta ttttcaagta
    16501 actcaataga tttttctatt cttatatgat ttagatatga tataaaagtt gtatttaaat
    16561 tacttttaaa aatcctagat atattagatg gattggttaa aaataatcta gcacaatcat
    16621 ttaactttaa gtcattgcta tagtttagat ttatatattc cagtatctca tttaataaat
    16681 cattattggt atattgatat ccaataattt tttctacaga cttagtaaat tctttcatat
    16741 ccaatggttt aaggagtata tcttttacat ttaatctcaa agctttttga gcatattcaa
    16801 aatagttaaa tgcagttatt actacaaagt ttattttttt agataaatga gatgtttttt
    16861 ctattactt
//
LOCUS       DAGQVA010000087        16797 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.087, whole genome shotgun sequence.
ACCESSION   DAGQVA010000087 DAGQVA010000000
VERSION     DAGQVA010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16797
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.087"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            288..2147
                     /locus_tag="MIV85_003152"
     CDS             288..2147
                     /locus_tag="MIV85_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2962474.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2439..3038)
                     /locus_tag="MIV85_003153"
     CDS             complement(2439..3038)
                     /locus_tag="MIV85_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBY2962475.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3141..3938)
                     /locus_tag="MIV85_003154"
     CDS             complement(3141..3938)
                     /locus_tag="MIV85_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBY2962476.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(4051..4156)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4248..5234)
                     /locus_tag="MIV85_003155"
     CDS             complement(4248..5234)
                     /locus_tag="MIV85_003155"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBY2962477.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5718..7448
                     /locus_tag="MIV85_003156"
     CDS             5718..7448
                     /locus_tag="MIV85_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBY2962478.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7558..7638
                     /locus_tag="MIV85_003157"
     tRNA            7558..7638
                     /locus_tag="MIV85_003157"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7592..7594,aa:Leu,seq:tag)
     gene            7973..8488
                     /locus_tag="MIV85_003158"
     CDS             7973..8488
                     /locus_tag="MIV85_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBY2962479.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8980..9084
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9294..11768
                     /gene="gcvPA"
                     /locus_tag="MIV85_003159"
     CDS             9294..11768
                     /gene="gcvPA"
                     /locus_tag="MIV85_003159"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBY2962480.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11768..13225
                     /gene="gcvPB"
                     /locus_tag="MIV85_003160"
     CDS             11768..13225
                     /gene="gcvPB"
                     /locus_tag="MIV85_003160"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBY2962481.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13648..16005
                     /locus_tag="MIV85_003161"
     CDS             13648..16005
                     /locus_tag="MIV85_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBY2962482.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(16091..16408)
                     /locus_tag="MIV85_003162"
     CDS             complement(16091..16408)
                     /locus_tag="MIV85_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBY2962483.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         6358 a         1937 c         2740 g         5762 t
ORIGIN      
        1 aatataatta agttatataa taatatataa ttataatgat ataattttaa taggtggttt
       61 gtaattaaaa agtttataaa ttatattaat agtaataatc tataagaact tatatattag
      121 aaaaaatttt gtatatatag aggactctaa agatgaacta tgtaaaacaa ggtttatata
      181 ttctaattgt atagaaaatt tattgtaaac gcatgtatat tattagaaaa aatagtttga
      241 aggtattcaa taaacataaa aaacaatata ggggataaag gtgttttatg aagagatttt
      301 tgaggagaat tatcttagtt ttatttattt tgttgatttt tataagtttt atttctatta
      361 aattaattca taatgttgga gattatggaa aattgattaa ttatgttggg attgttcgtg
      421 gagctagcca acgtctaact aaactagaga tgaatcatca accaaatgat gaattaatag
      481 aatatattga tgaaatccta caggagttga ttacagggca tggagattat ggtttagtaa
      541 tcactgattg taatgaatac aatgaggact tacttttatt agaaaaaaag tgggaagatt
      601 taaatattga aattaaaaaa gtaagaatga aagaacagaa taaccagtta ttaagtataa
      661 gtgaagagtt tttttctctt gcaaatgata cagtgtttaa aatagaaaac ttttctaaag
      721 aaaaaagtaa ttacttaatg actttaataa taattatatc tattataggt atattagcat
      781 gtatcatatt gattttacaa tatagtaaaa aaatggttag actggaaaaa ttaaatgtag
      841 atttaaaaaa tattgcatat aaagatgaac taacaggagt aaatactata gaaaaattta
      901 aattggatgc aaatcaaaat atttgtatac ataaggataa gaaatttgct gtattctata
      961 ttgattttga aaactttaaa tacattaatg atatatttgg atatgattat ggtgacatga
     1021 tactgaaaag atatgctaat cttatgatga atgacatagg gaaatatgaa atatttgcaa
     1081 gagaaattgc agatagattt gttgcgttaa gatgctatgt agataaggaa gatttagtgg
     1141 taagacaacg agatgtagac aatgaactaa ttaatataac aaatgaaatt aaaaataaac
     1201 atagtattac tgttgttagt ggaatttgtt gtattgaaga tgtaaatgaa aaattaagta
     1261 tagatggttt aataaataga gcaaattttg cacaaaaaac tgttaagaat aaaccaggta
     1321 ctaattatgc tttttataat gacagtattc gtaaaaaaat gattgaagaa aatactatca
     1381 agagtagaat acatgaagct attgaaaaaa gagaatttat agtttattta cagcctaaag
     1441 ttaatttaca tagtcaaaaa ataaattgtg cagaagcttt agttcgttgg cttactccgg
     1501 ataaaggtat tatatcgcca gcaatattta ttccagtact tgagaagaat ttttttattg
     1561 ccttagtaga taagtatgtt tttgaggagg tttgtaaatg gattagaaag aggttagatg
     1621 aaaataaacc ttttgttcag atatcagtta atgtttcaag aatacaattt tataacacta
     1681 aatttgtaga aacttattcc aatatacaaa ataaatacag gatacctaaa aatactatag
     1741 aaattgaatt tacagagagt gttgcttttg agaatcaaaa acatcttttg gaaattatac
     1801 atgatttgca tgaaaatgga tttacttgtt ctttagatga ttttggaaaa ggttattcgt
     1861 ctttaagtgt tttaaaagat ttaccatttg atgttttaaa gcttgattct atgtttttca
     1921 aggctagttt agataaagat aaagagaaaa tagtaataaa aaatattgta catatgttaa
     1981 aagaacttaa tatcacaact gttgctgagg gcattgaatg caaggaacaa gttgaatttc
     2041 ttagggatat tgggtgtgat ttagttcagg gatttgtatt ttataaacca atgccaatat
     2101 tagaatttga aaaaatattg gataaagagt ttgtttataa tagctaaaat gtactttata
     2161 aaatatgaac taattaagta aaattatttt gtactgaata aatttttact ttatttacag
     2221 aataatgatt atttacagaa aagcgcgaaa agtgtattcc tttaagtgtg ggatggatag
     2281 cacaaataga ggagaaaaaa tattggccat ataagaatgc ataataatat aaatatttga
     2341 aaggtcagca ttatataaaa attaaaaaga aaataaataa tttttctata aaaaagagac
     2401 tatgagaaaa tttactcata gtctcctaaa taatgtattt attttcttcc tgcaacccat
     2461 tttaatcccc aatgaaattc agtatccatt tctctatgac ctttgaagta tttaactact
     2521 ttttcaacac tgaatgtctc atcatttaca ttttctatca atgctattga acacatatta
     2581 tagccatttt tatgttcatc aagtttgaca actaagtctg aatcttgttt ttgtttgatt
     2641 gttacaattc catcagcttc agaccagtta gctacacctt cgtatataaa agcataaata
     2701 agtattcttt ttatatcttt tattttatta ccatttattc ttaaattttc tccttgtgta
     2761 ttacttcctg ttctgtcatc tccatctaat tgagcaaaag gtggattgtc taaactacca
     2821 aaggcatttc ctaatgcttg aacagctcct tttacaccat ttttcatctc aaataggcaa
     2881 cccaaatcta aatctatatt actgcttctt aaagagccaa aaaaaccctt tttttgtact
     2941 ttttgattcc aatttaaatt aactaagatt tcacctaaat cgctattttc cttttttgta
     3001 aggtttattt tttgtccctt ttttaattct atagccatag taatcttcct ccacaaacat
     3061 agatttattt aaatggtagc acttaataag tcaatattca acaagattag aataataata
     3121 ttaaaattat actaaatata ctaaaaagta ggaatcacaa tacctttgta tttttcttca
     3181 attaagcttc ttgctttatc tgatgtaaga acatcttgta gaactttaat cttttcactg
     3241 tctttatctt cagttctaaa tgctaaaaga tttgcatact cgtcatttat aggagctgta
     3301 taaattccgt ttttcttggc atcaagacca gcaggtacag cataagtagt atctataaat
     3361 gcagcagtca catctggaag agaagatgga atttgagcaa tatctaactc tttgaattgt
     3421 attccctttg gattttctat tatgtcctta ggactaacta atccatcccc tttaggtaac
     3481 gttaaaagtc caatactttc aaggtatcta aggttcttag aacaagaaga tgggttattg
     3541 cttattgcaa ttgtatctcc ttttttaaat tcatcaacag attttatctt ataagagtaa
     3601 agtattgctg ggcatacata tagtttttta ccagccatta ttttgtaacc tttggcctta
     3661 acagcttctt ttagataagg ttcatgttga aatagatttg catcaatttc accattattt
     3721 aaagcttcgt ttggaagtat gtaatcatca aagtttttaa cttctaaagt atatcctttt
     3781 tctttaataa gtggttttaa ttcttctaat aactctcctc ctggaactaa agtagcacca
     3841 acaacaattt ttttatcatc tttagcttta gaacatccaa ccacagctaa agttaatact
     3901 agacataata acaaacataa taattttttg aatttcatat aaattccctc ctgaatataa
     3961 ttgattagtt aaaaataaaa taccattctt tatcacactg caaaataaaa ataagcctga
     4021 gtttaaactc aggctttaaa agctaattta gactcatctt tcagtataat actgcaggat
     4081 ttagcaccaa tgtatataaa aatatactgg ttgctgggtt tcatagggcc agtcccttca
     4141 ccactctgga taagaagtat caatttttaa ttatgttata aatattatca tgatttttta
     4201 cgtctgtaaa cataatttta taaatatttt aaaatcttta atgtatttta tttaacacct
     4261 aaaattccag aaactagaat atcagtatca gcacctaaga aatagtcatt tatttcaata
     4321 gaatccagag tatttctcaa agcattttct tcatgcctta taccaataag tttattttct
     4381 acaaatgcaa catcacattt tccaaaaaaa tctccaaaaa attttatact agttattatg
     4441 cctttatcaa catttaaatt aaactcaaca tttccaccag aatattttaa ttcatttgaa
     4501 agagtatatt ttggtgaatt accaaaattc caatcccaag tttcgtattt tgatttagta
     4561 agcttttcta tttgttttat atcatgctca ctcaaacaat aattagtatt atcagtattt
     4621 gttttagaaa gataatccat tatagcatct ttaaattcta atatgtccat ttttgaatgt
     4681 aaatgttcac ttatattggt tacacgagat tttacagatt ttattccttt tccttcaaat
     4741 tttataggtt taacctttaa tgcttttgag aggtcattta tttcagatga aaataaaaga
     4801 gtaccatgat gcattacttt gtttttgtag ttgtattgag catttccaga aaatttcttg
     4861 ccatctataa gaaggtcatt tcttccagaa aattcggcat tgacatctag tgttttaagt
     4921 aaatctatta tgggctgagt gaatcttctg aaatcactaa aattattatt gttacaagct
     4981 ataaatgtaa aatttatatt tcccaaatca tgaaatacag ctccaccacc agactgtctc
     5041 ctaacgacag gtatagaata ttcttttata tattctaaat ttatttcaga aagtgtgttt
     5101 tggttttttc caacaattat agaaggttca ttcctccata aaataaataa gtcttcatca
     5161 aaatttttta gaagatattc ttccattgct aaattaaaat aagggtttgt tttttcatta
     5221 taaattaata acattaaagt agttcctcca tagaattgat aaaattttta ttatgaatac
     5281 aattaatttt ataattcgac aataatataa aaactccttt aaattagaaa ttttaaaaac
     5341 taccttgcaa agtttaaata aataatatat actcaaaata tgtttaataa aagtgaatag
     5401 aagggtagag gcgcaataat ctatcagtac taataaggag ttaagcacag agatttatta
     5461 ggaaaggaga tattgccgaa gttttataat cgatgcttta agattatatt gctgggggta
     5521 catagaaaat atgtacaact gtcacaggtt tatttgtggt gagctatcat ttaaggaatt
     5581 atattatatt tatttttact attgttgata tattgtaatg tttaagcctt gagtgtttac
     5641 cactcaaggc ttttttagtt ttattgtaac ataataccct gtacagttca caaaattaaa
     5701 aggagaggga gatttatatg aggaacaaaa aaattaatat tatttttctg acgacaatca
     5761 tgttcataat gtcaacagta atggtttttg cagaagaaga tatagacact attgcactag
     5821 ccaatgcaga aaaatttggg attttaactt taataccacc attagttgct ataatacttg
     5881 catttataac taaaaacgta ataatttctt tacttatagg tattctttct ggtagtttta
     5941 taattaaagc tagtggtatt aatgtttttg cgacatttat acaggcattt ttagatttag
     6001 tagacagagc tttagtatct ttagcagacc cttggaatgc agggataata ctacaggttt
     6061 tggcaattgg aggagtaata aatcttgttg ctaaaatggg aggagctaaa gctatagctg
     6121 aagcacttgc taaaagagca aagtcagcaa aagggacaca gcttataaca tggtttttgg
     6181 ggcttttagt attctttgat gattatgcca attcactaat agtaggtcct atgatgagac
     6241 ctgttgcaga taaaatgaaa atatcgagag aaaagctagc atttataata gatgccacag
     6301 cagcaccagt tgctggttta gctataatat ctacatggat aggtcttgag gttggtttaa
     6361 tacatgatgc ttttgaaagt ataagtatag atgtagatgc atttggtata tttttaaata
     6421 caataccatt tagattttac aatatattaa tattagcttt cattgtaata tcagcattat
     6481 tattaaaaga atttggtcca atgagaaaag ctgagataaa atctagaagt agaaaaatta
     6541 gtatagacct tgatgaaggc gtagaagagt tggatgattt agctccaaaa aatggagtaa
     6601 aattgagtgt atggaatgct ataatcccaa taggaacatt gataatagtt gcattagcat
     6661 cattttatta tagtggatat acatctataa tgggaggaga cgataaggct ctgatacaac
     6721 tatttacaaa ttctccatat tcttttgaag caataaaaga agcatttagt gcatctgatg
     6781 catctagagc attattccag tctgcacttg ttgcaagttt agttgctatt ataatggctg
     6841 tagtaaaaaa gatttttaca atatcagaag caattgatgt ttggatagat ggaatgaaaa
     6901 gtttagtaat cactggtgta atattaatac ttgcatggtc attaagttca gtaataaaag
     6961 agttaggtac agctaaattt ttaatacacc tattatcagg ttcactacca ccattcttat
     7021 taccaagttt aatatttggt ttaggagcaa taatatcttt tgctactgga acagcttatg
     7081 gaacaatggg tatacttatg ccacttgcaa ttccattagc atactcatta aatcctgata
     7141 tgtcttatgt aatagtaagt actagtgcag ttttaacagg tgcaatattt ggagaccatt
     7201 gttctccaat ttcagataca acaatacttt cttcaatggg agctggctgt aatcatatag
     7261 accatgttaa cactcaaatg ccatatgcta tatttacagc agtaatcact attgtatttg
     7321 ggtatatacc agctggactt ggattgccaa tatatatagt attaccagtg gcaatagctg
     7381 ctatatttgt aggtattcaa ataattggta agaaagttga tgaagcggaa atagaacttg
     7441 tagaataaag atataaataa gtttcacctt ttattatcac tattttgtta gtttttagat
     7501 aattttaaaa agttattgaa aataatggcg aaatatagta aaataaaaga gtgataagcg
     7561 gatgtggcgg aattggcaga cgcactagac ttaggatcta gcgccattgg cgtgggggtt
     7621 cgactccctt catccgcact ttacagtact taattgtact gaaaaaaact ggggttgctg
     7681 gctttcggag tgggctatcc cgtttttatt tttttgtata tataatagat tggcacttta
     7741 gtataaggtg ctttttttat aggcaaaaac agtacattta tttctgtttt attatcattc
     7801 atctattaga atatacttta gttaagaatg tgttaataag cagtgttcac attcttgata
     7861 aaatgtggaa taatatgtat ttttactaag acggaaatga aataattaaa ccattaaata
     7921 atattataag atgatgaata agtagataaa tcaaattttg taggaggata ttatggaaaa
     7981 atatatatgg ttgtttccat tactttttat ttttcatgat atggaagaga taataggttt
     8041 tggaatatgg cttaaaaaaa ataaatcaat gcttgataag aagtatccat ttatcagtaa
     8101 agtttatgaa aattatagta ctgaaggcat ggcatttgct gtgtttgaag aatttatttt
     8161 atgcattatt ttctgtatac ttacagttat aacagagaat cagtatgtat atctactatg
     8221 gttaggtagt tttatagcat ataccttaca tttggtaatt catatagggc agtcaatcat
     8281 aataagaaaa tatatacctt cacttattac cagtatcata tgcttaccaa taagcatttg
     8341 gtgtataagt aagagtattt atatagttga ttgtgaaatg agtacaacaa ttctgtacag
     8401 tataattggc attataattg tagcattgaa tttaaagttt gcacagtcgc tgattggaaa
     8461 atttacaaag tggatgtcaa acatataaat tttagtttat tggacagttc aaggaatcag
     8521 aaattggaat tttatagtat taatatttta tggtattaat ataatgtata aaattttata
     8581 gcaatgtatt tcataagtat aaagtgacta gaattttaag aaatatacaa attctataaa
     8641 aactaaataa tttcaagtat attttaaaaa tcttattttt cacaagttta aaattgtaaa
     8701 cgatttcatc aagtctatga atatactttt aacatgttat agtaaatctc aatataaatt
     8761 tacatttggt tctttgtgtg ttattttaat aataaattaa gtgaaaatgt tattttacat
     8821 taatatataa tatctttgca taagagtgaa taatataaaa gagaaataat tgataataaa
     8881 aacttaacaa aaaaattaat acataaaaaa aaataaatat aatgtgttga catttaattg
     8941 aaatattcat acaataaaat tgaaaataaa tatttccaaa tgagattagc gagagagtcc
     9001 tttatacgaa aaggcgccga agaagaaatt taagaaatgc caatttttag agaagctttc
     9061 aggcaaaaat atcgctaatt gatgggactc tggagagact taagttaaga tactataagt
     9121 caccgaagaa gcaaaataat attaaattat taaatctttc aggtatacaa acagggatat
     9181 ataggctagg attattttcc atgctgatat atcttttttt tatgaaaaag tacaggaaat
     9241 aatatcaaag ttacttaaat acagtaggtc taattttcta gggagggtta tatatgaatg
     9301 aattgaaaag agtatctttg tacaatatac acaaagagct tggagcaaaa cttgttgaat
     9361 ttgctggttg ggaaatgcct ttagaatatg agggtataaa taaagagcat gagaaggtca
     9421 gaaaaagtgc aggtatattt gatgtatctc atatgggaga ggtacagata aagggagcag
     9481 agtcagaaaa atttatacaa aacctagtta caaatgatat aagcgcatta aagataaatg
     9541 atattatata tacacctatg tgttatgaaa atggtggagt agttgatgat ttattaatat
     9601 ataaatttgg tgaagaagat tatttattag taataaatgc aggtaatata gataaagatg
     9661 tagcatggat aataaaacaa agtgaaggat acaatgtaga tataaaaaat atatctagtg
     9721 aagtgagtca attagcaatt caaggaccta aagcagaaga aattcttcaa aaaatcacag
     9781 atatagactt aaactcaata aaattttata agtcaattcc atcaacaaaa gtatgtggtt
     9841 gtccttgttt agtttcaaga acaggatata ctggggaaga tgggtttgag atatactgta
     9901 aaaataaata tgtagaaata atttggaatg aagttctaaa ggttggagga gaagatatat
     9961 gtccagctgg tctaggttgt agggatactt tgagatttga agcagctcta cctctatatg
    10021 gacatgaaat aaatgaacac atatctccaa ttgaaggtgg tttatctatc tttgtgaaaa
    10081 caaataaaga atcatttatt ggcaaatcaa ttttatcaaa agaaaaagaa agtggagcta
    10141 aaagaaagtt agtaggattt gaaatgcaag gtaaaggaat gcctagaaat ggatatgata
    10201 taaggattgg tgataaaaca gttggatttg taacaacagg atgtgcatct ccaacgacag
    10261 gaaaaatttt aggtatggga attatagatt ctgaatatgc aaaagtagga aatgaaatag
    10321 gtatagcaat cagaaaaaaa gttgttcctg ctgtgatagt taagaaacct ttttataaaa
    10381 aacaatataa aaaagataat attatattaa acaaagaaaa taaattttca tatatacctg
    10441 ctacaagtga agataaatca aaaatgttaa aagtagttgg attaaattcg gttgatgaat
    10501 tattttcaga tataccagaa gaagtaaaat taaaaagaga tttaaatttg gaaattggaa
    10561 aatctgaatt agaggtaagc aaaatagtaa aaagattgtc agaagaaaat ttaagtttag
    10621 aagacttgac ttgttttctt ggtgctggtg catatgacca ttatatacca tcaattataa
    10681 aacatataac ttcaagatct gaattttata cagcatatac tccatatcaa gctgaaataa
    10741 gtcagggaac tttacaagta gtttttgaat ttcaatctat gattgcagaa attacaggta
    10801 tggaaattgc aaatgcatca atgtatgatg gagcaactgc tgcaatagaa gcatgtataa
    10861 tggcaatgaa tcagactaga aaaagtaaaa tagtagtgtc aaaaactatt catcctgaaa
    10921 ctttgtcaat attaagaact tacttacaat ataaagattg tgagatagta gaaattgact
    10981 tttgtaatga atatggcact acagatatag aaaaattaaa agcttctgta gacaaagata
    11041 cagcatgtgt tcttatacaa actcctaatt tctttggaat tattgaagaa atggaagaaa
    11101 tagaaaagat aactcatgaa aataaggcta tgttaattat gagtgtagac ccaatatcat
    11161 taggagtttt aaaaacacca ggtgagatag gtgcagatat tgttgttgga gaagctcaat
    11221 cacttggaaa ccctcttaat tttggaggtc cttatgtagg atttttagct agcaaatcta
    11281 aatatactag aaaaatgcca ggaagaatag ttgggcaaag tttagatgta gaaggtaaaa
    11341 ttgcatatgt attaacttta caaactagag aacagcatgt aagaagagaa aaagcaactt
    11401 ctaatatatg ttcaaatcaa gctttaaatg ctcttgtagc ttcaatatat atagctacta
    11461 tgggtaaaga aggatttaaa gaggttggta tgcagtctat gaaaaaagca cattatactt
    11521 acaataagct tgtacaaact ggaaaatata agccaatatt taaaggtaag tttttcaaag
    11581 aatttgctgt acaaggaaat cttaatatag aaactataaa tgataaactc ttagaagaaa
    11641 atatattagg tggttataat ttagaataca attatccaga attaaaaaat tcaactttgc
    11701 tttgtgtgac tgagaaaaga agcaaagagg aaatagataa gttagttgga ataatggagg
    11761 gattataatg aaagaataca atagtttgtt gatagatata tctaaaaaag gtaggaaagc
    11821 atactcactt ccaaagttag atatagatga tataaaaata gaaaatatga ttgaccaaga
    11881 tatggcaaga caaagtgagt tgaatttgcc agaagttggt gaattagaat tagttagaca
    11941 ttatacatta ttatcaaata aaaactttgg agttgataca ggtttttatc ctttgggttc
    12001 ttgtactatg aaatataatc ctaaaataaa tgaagatatg gcagcacttc caaactttac
    12061 tggaatgcat ccataccaat cttcggatac agctcaaggt tctctttctt tgatgtatga
    12121 tttatcaaga agacttgcag aaattacagg tatggatgaa gttacactac aaccttcagc
    12181 aggttctcat ggtgagttta cagggcttat gattataaaa gcatatcatg aaaatagagg
    12241 tgaccataag agaaccaaag tgataattcc agattctgca catggaacaa atccagcaag
    12301 tgcagctatg gcaaactttg atgtgattca aatagcatct gataaaaatg gagctgtaga
    12361 cataaatgca ttaaaagagg ttttgaatga tgaagtagca gctcttatgc ttactaatcc
    12421 aagtactctt ggtttatttg aaaaaaatat aaaagaaata gctactcttg tacatgaagc
    12481 aggaggactt ttgtactatg atggtgcaaa catgaacgct attatgggga taacaagacc
    12541 tggagatatg gggtttgatg tggttcatct taatcttcat aagacttttt caactcctca
    12601 tggaggtgga ggtccaggag ctggtcctgt tggagttaaa aaagaattag tacctttttt
    12661 accaatacca gtaattgaaa gaaaagaaga taagtatgta ctaaattatg atagagaaaa
    12721 atctattggg aaaattaaaa atttctatgg taattttgga gttcttgtaa gagcttacac
    12781 atatatacta actatgggaa gggatggact taaagaggct agtgaaatgg cagttttaaa
    12841 tgctaattat ataaaggaaa gtataaaaga tgattatatt ttgccaatag ataccttgtg
    12901 taagcatgag tttgtattag gtggattgcc aagaggagag gccaatataa aaactatcga
    12961 tattgcaaaa agactactag attatggata ccatcctcca acaatgtact ttcctcttat
    13021 tataaatgag gcacttatga tagaacctac agaaagtgag agtatagaga cattagatag
    13081 ttttatagaa gctatgaaaa gtgttgctaa agaggcaaag gaagaaccag aactattgaa
    13141 aactgctcca cataatactt tggtcaaaag agtagatgat gcaagggcag taaagaaacc
    13201 tatactaaca tggtcacaaa gataaatagt taaaaagtag agatttaaag tataaagaga
    13261 attaaatttg taagaaaaag ctatctaact taatctagtt tagatagctt ttttgtatat
    13321 tagtatgtat ggtattttct atataaagtt ttaaattata ttagtgctta tatagaatat
    13381 tgatatgatg attatgtata gatattaata agaattgttg aatttatctt gccttaactt
    13441 tatttactct tttatattaa gaaaaactta actaaaatat agcgaaattc ataaaaattt
    13501 aggaaatctt aagaattata atatttaaat ctttagattt atattttatt atataaacta
    13561 tagaataata aaataaaaaa attgagaatt ttataatata tttgtagatt tgagtataaa
    13621 aaagtgctaa gttgaaagga gtaaaatatg gataaggtta atttagaaag gtatagttgt
    13681 gatataaatg ttggtttaaa taaaaatcaa cttcaaagta gaatagatga taatttaatt
    13741 aatgcatttg ataatggaaa aaccaaaaca tataaacaaa tttttaaaga caatatattt
    13801 acacttttta atctcataaa tattgtttta gtctgtttat tagtttcagt tggttctttt
    13861 aaaaatacct tatttatatt tattgctgta attaatacta ttataggagt aatacaagag
    13921 ataagagcta aaagattatt ggacaatcta tctgttatag tttcaaataa ggtatctgtc
    13981 ataagagaaa aagagaaaaa agagattgat gtacaagaat tagtattaga tgatattatg
    14041 attttaaaaa caggtaatca aatttgtgca gattcaaaag ttttaaatgg aaaattagag
    14101 gtaaatgagt ctttggttac aggtgaatct gatattatta taaaaaataa aggcgatttt
    14161 ttatattctg gaagttttgt agtttctgga gaagcttttg taagagttga aaatatagga
    14221 aaagataact atgcaaataa gatagctaat gatgcaaaga tttctaaaaa acataattct
    14281 caacttagaa attcattaaa tgcaatatta aaaattgtag gtataataat aattccttta
    14341 ggaattatat tgtttgcaaa acaacatttt ggaaatggag attctatagc tacatctgta
    14401 gtaggtacag tggcagctgt aaatggtatg ataccagagg gattaacatt acttacgagc
    14461 attgctctag ctgtaggaac tataaaactt gctagtcata aaactttagt gcaagaactg
    14521 tactgtgtag agactcttgc tagagttgat acactatgtc ttgataagac aggtacaatt
    14581 acagaaggta aaatgcaagt tgatgatata gtaatgttgg aagaagtgga tattaatgaa
    14641 ataatgggga atatatgtaa ttctctcaaa gatgataatg caacactaaa tgcaataaga
    14701 gataagtata atgttttaga tacgtataaa gctaagaatt taataccatt ttcttcagaa
    14761 agaaaataca gtggggttac ctttgaaaat aaaggtacat atttattagg tgcatttgag
    14821 tttatattta aggaaaaaaa taaaaaactt aggatagaag ttgaaagata ttctaaaaaa
    14881 ggaaacagag taatagtttt agctcatagt gattcttata tggaagataa taatattcct
    14941 gaagatataa agccactagc ttttatattg atattggata aaattagaga tgaagctaag
    15001 gaaactttag aattttttta caatgaaggt gtagatataa aaattatatc tggtgacaat
    15061 cctataacag taagtgaggt agctagaaaa gcaggtctta aaacagctag taattttatt
    15121 gatgcaacaa cacttaaaaa tgatagtgat atatacaaag cagttgataa atacagtgtt
    15181 tttggaaggg taagcccaca acagaaaaaa caaatgattt tagcattaaa aaaacaaaat
    15241 catacagtag ctatgactgg agatggtgta aatgatgtac tagcacttaa agaagcggat
    15301 tgtagcattg ccatggcatc tggaagtgat gttactaaga atgtgtctaa tttagtctta
    15361 ttagattcaa actttgcatc aatgccaaag gttgttatgg agggaagaaa agtaattaat
    15421 aacattcaaa gagcatcttc tttgttttta gtaaagacaa ttttttcatt cttcttgtcg
    15481 ttattaacat tattcttctt cagtagacag tatccatttg ttcctataca attatcactc
    15541 attggggctg taacagtggg tataccatca ttcttcttag ctcttgaagc aaacaaaagt
    15601 agaatttcag gaaatttttt actcaatata ttaaaaaatg ctttaccagg agcactatgt
    15661 gtgacagtaa atgtaattat tgtttacaat atagttgaat atttaggtta tagttcaagt
    15721 gtattttcca caatgtgtgc tatattaact ggtgtatgtg gtcttttaat attgagacaa
    15781 caatgtttgc catttaataa agaaagatta tttttaatag taagtatgac tattgcattt
    15841 gttattggga ttctattttt aggtggatta ttctcatttg tagcattgag tagagaatta
    15901 attctcataa ctatggcatt agcaatatta atgccaatta tgataaaagt tatgttattt
    15961 gtcttagatg agatattaga gacaattgtt ccagatttaa attaatttta aaatgatata
    16021 aataagagca gttttagttg aactgctctt tttagatgtg tttaatttta tgtaagaata
    16081 tgtattttta ttaatcagct atatatgagc aacagtagtc aacaacttca ttaaccttta
    16141 agtcaaaact tgaatcacta ggaacattaa atttttgccc ttctttataa gttacaaact
    16201 cattgcttcc aggcagtttt acatccatac ttccagcaag catctccatt atttcttctt
    16261 ctctagtaga aaaagtgtat tctcctggca acattaatcc taaagttttt ctttctccat
    16321 taggcagtat tattactctg ctacttacct taccatcaaa ataaacgttt gccttcttta
    16381 ctgcagtaac attcttaaat tcactcatta gataaaacct ccaaaattat ttgtacatat
    16441 atattatata aaaataatgt aaaaaatgct atatatttac aaaaaaattt agtatttatt
    16501 aaaaaaatta ataagaataa aaaagaggtg aaattgctta aattgataaa aaatataaaa
    16561 taaattgcaa agtaagcaag aaaagaataa gttgaagagt tatatattat aaatattaaa
    16621 aattttagta ttaataaaaa agatattaca ttaatatgaa aatataggag attagaagtg
    16681 tttgattaaa aaatagctac acacacttgt gactttagtc atgagttagt agctaaaata
    16741 gtcagcatat agggaaactt atatgtagag ataggataga acctatccaa tactact
//
LOCUS       DAGQVA010000088        16599 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.088, whole genome shotgun sequence.
ACCESSION   DAGQVA010000088 DAGQVA010000000
VERSION     DAGQVA010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16599
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.088"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(271..603)
                     /locus_tag="MIV85_003163"
     CDS             complement(271..603)
                     /locus_tag="MIV85_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBY2962484.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(847..1488)
                     /locus_tag="MIV85_003164"
     CDS             complement(847..1488)
                     /locus_tag="MIV85_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBY2962485.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFVYSYLMYKISGKNN"
     gene            complement(1469..1762)
                     /locus_tag="MIV85_003165"
     CDS             complement(1469..1762)
                     /locus_tag="MIV85_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBY2962486.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            2155..2205
                     /locus_tag="MIV85_003166"
     CDS             2155..2205
                     /locus_tag="MIV85_003166"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962487.1"
                     /translation="MTEYIYYYNNKRIKKN"
     gene            complement(2731..3483)
                     /locus_tag="MIV85_003167"
     CDS             complement(2731..3483)
                     /locus_tag="MIV85_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBY2962488.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VAMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(3542..5197)
                     /locus_tag="MIV85_003168"
     CDS             complement(3542..5197)
                     /locus_tag="MIV85_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962489.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIYIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSVSDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(6469..7548)
                     /locus_tag="MIV85_003169"
     CDS             complement(6469..7548)
                     /locus_tag="MIV85_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2962490.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(7632..8288)
                     /locus_tag="MIV85_003170"
     CDS             complement(7632..8288)
                     /locus_tag="MIV85_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2962491.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            8610..8816
                     /locus_tag="MIV85_003171"
     CDS             8610..8816
                     /locus_tag="MIV85_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962492.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCFAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(8969..9397)
                     /locus_tag="MIV85_003172"
     CDS             complement(8969..9397)
                     /locus_tag="MIV85_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBY2962493.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(9873..10811)
                     /locus_tag="MIV85_003173"
     CDS             complement(9873..10811)
                     /locus_tag="MIV85_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBY2962494.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            complement(11325..12137)
                     /locus_tag="MIV85_003174"
     CDS             complement(11325..12137)
                     /locus_tag="MIV85_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2962495.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(12160..12792)
                     /locus_tag="MIV85_003175"
     CDS             complement(12160..12792)
                     /locus_tag="MIV85_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2962496.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            complement(13136..14791)
                     /gene="ilvD"
                     /locus_tag="MIV85_003176"
     CDS             complement(13136..14791)
                     /gene="ilvD"
                     /locus_tag="MIV85_003176"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBY2962497.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLNFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(15115..15414)
                     /locus_tag="MIV85_003177"
     CDS             complement(15115..15414)
                     /locus_tag="MIV85_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962498.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            15674..16354
                     /locus_tag="MIV85_003178"
     CDS             15674..16354
                     /locus_tag="MIV85_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBY2962499.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT         5522 a         2859 c         1790 g         6428 t
ORIGIN      
        1 gttcataaaa atacaaatat gtaaatataa tcaccttaat attcaattta tttaaaataa
       61 aaaatgtata aaagatttaa taatgacaat atactattct caatacaatc tatgatgtaa
      121 ataatttaaa actactatat tatttaaaaa tttatattta tatatgcaat tctaaaaact
      181 taataagaag tgaacttaga aaataaagct taatttcaaa ggcttaaata gactattatt
      241 attagtctaa ataaactacg tgtatcaaaa ttatatatta aattcttcta aaatttttat
      301 tgcaaatctt gcgtttggat atgtaataga ccctccacca attacaccta tttttatagc
      361 ttctataatt tcatctttac ttgctccaga attaatacaa ccctcaatat gataacaaat
      421 acactcatca catcggctta aaattgaaat agctagtccc attaattcct tatttttttt
      481 acttatagcc ccttctgaat aagtcttatc atcaaggctt ccaaatactc taaaaaactc
      541 atctgtttca cttaattttt tattgtaaaa tcccctatat tctttcattt ctctagtatt
      601 catcttctac ctcctatttt tttcttataa gagtatcaca ctgtacttat attttcaata
      661 ttaaatacaa attttcattt tatgttcatt agcctaattt atattatttt ttgaaatctc
      721 aataagttat catataagta agattttttc agaactaaaa tagaaatctc agtaatttct
      781 ttattatcta tctcagttct gaaatatatt attcttatcc aaacattatt atagtgatta
      841 attatattag ttatttttac ctgaaatttt atacatcaaa taagaatata caaatggtag
      901 tattacaatt acaaagatta caaagatatt ataaaaagga atattaataa atgcattaat
      961 aattaataat attccaccaa taagccaaat ccatccagct aaatggtgtg tcttattcca
     1021 attatcttca tcattaagag tccatggtaa aattattcct actgagtaat ttcgtttaca
     1081 tttaggaaga tagtttccaa ataaaataac tattattcct aaaattaatc ctgtataaaa
     1141 attagactcc aaactaactc ctgttgaata taaaaccatc attatttgta taattactga
     1201 aagtatagca actccccatt ttgataaatt ttgtataaca tttgaaaaat tagctttctt
     1261 aggctcattc tcaagtctaa accatgtata caaatggata catagcatta acaatggtac
     1321 accaaaagct gctataacct ttggagcata attatctgga tttccataat tatcaaaatg
     1381 aattgcaact tcatttggta atctattata aaaatatatt gatacaataa atggtataaa
     1441 acatattaaa gtagataaaa taaattgttt atttatcgct tttttcatta tctttttctc
     1501 ccttctccat aaattgcgaa aaccaaagca taacctcttc gaaaactgaa atatttattt
     1561 cgtagaaaat aaagttctta tactttgttt caaatatgag tcctgccttt tttagttgag
     1621 atagatgata agaaattgta gcattcgtca tattaaattt ttcactaatt tctcctgctg
     1681 acattttatt ctccctcaac ataaccaata tttctcttct tatagggtct gaaagagctt
     1741 tgaatgtttc tggaaacccc aacaccatca cctcgctatt tagaatttca tctaaataga
     1801 atataacata acatccattt tatttcaata actatttaga attttttcta aatagttatt
     1861 tctaaatatt tattgaaaat tttcatatta agattctcaa tttacttaag tcgcttttat
     1921 ttaatcttac tttatctaat ttttttaact taacaaaagt gtattgcacc ataattgtta
     1981 aagcaaaaac ctaatgactg aggtacttat atatataaca atacttttaa ttttaaatta
     2041 aaagtagcta aacccaattt aaaaagtagt taagtcctat ttaaatagaa aagaatgaaa
     2101 cgagaaatat actgtataaa agtacataaa aacatctact aattagatac aactataaca
     2161 gaatatattt attattataa taacaaaaga ataaaaaaaa attaatttag catagccttg
     2221 ttaaatatag atttgaatat gaatttaaag ttatgtaaaa ttaaaaatac aggaatgaaa
     2281 attccattcc tgtataaaat ctaacttttg agtctcagta caatcttatt ttgagacaat
     2341 cttttttgtt ttatattttc ttatatttaa aatataacgc atatcttatg caacatattc
     2401 atatttttct ttatattctt tcatcgcatc attccaagcg tcttgtactg ttacacctct
     2461 tttattagca attttttgtg ccagttcaat tatcttcata gctcttcttg atatgttcat
     2521 aaacattcct cctacaaatt accatatatt tcatatatat aaatcaaggt tatattttta
     2581 tgatatataa tccttctatt gtaagattac agtttatatg tgtattatat atgaactata
     2641 ttagaagata attagaattt ttataaagct atatgattag attaaatata aaagctttac
     2701 aattacttat aaatttaaaa agtctataaa ctaaactaat gtttgatata ccaattttac
     2761 gaccataaat aatgccatta ctaaaaatat tggttttatc atctttgaac ctttctttat
     2821 agcaacttta gcacctacat aagctcccat tatcatcact aatgcaaaca ctatagcaat
     2881 tttataatct acttgaccat ttatcatgaa taataacaat gaagttatat tacttgttaa
     2941 gtttaatatt tttgtatttg cagaagcatg taaaaaatca tatccatata tttttataaa
     3001 tccaaaagtc aaaaaagttc ctgtacctgg accaaaaaaa ccatcataaa aacccattat
     3061 aagagccata agcatcccta gtcttaaatt tttcttatta acagcttcaa aattatcttc
     3121 ttgacctaaa tttttagaaa taaaggtgta aatagccact attaaaatca tagccacaac
     3181 caaaacattt aatatctctt cacttattga taatacacat ctcacaccta gaacactacc
     3241 aataatagta aatggtacta atttttttaa aaggttgtta ttaatttttc cagactttgc
     3301 atatctatag gcactactta tacatcctgc tgatgctgca aatttatttg taccaatggc
     3361 aagatgtact ggcactccaa ttgccataag aacaggcatg cttataagtc ctcctcctcc
     3421 tgctatagaa tctacaaaag cagctaaaaa cccccctata cataaaaaaa taactgaaaa
     3481 cataaaattc ctccatcatt ctctttcaat ttttcttaca atatatatta tataatctta
     3541 tttaatactt attatccagc atattctttc tatattcatt tggagttata ctattaaact
     3601 tcttaaatat ttgtgaaaaa taactactgt tattaaaacc tactttctta caaatatcac
     3661 taacactcat gcttctatct aacagatatt ttttagattc ttctatccta agaagattta
     3721 tatactcagt tattgaaact ttatttcttt cattaaaaat agaactcaaa taatttggac
     3781 ttataaaaaa aacatctgat atactattca aatttatatt ttctttataa tattttttta
     3841 tatattcgtt tatattttca attagatttc ctttatcttt tctccaaaat gctctattct
     3901 tatcaataca ctctttggaa aattcaaata atacattcca taaatcttca tcactgttta
     3961 caagtgatat ttttttatta tatttatttc ttaaataaga tataagtttt aaatcctcta
     4021 aatctctaag cactgttcta gacaatacaa atatcatttc ctgaatagta tctctaacat
     4081 cattatatct taatttgttt gtatctatta gattataaac accttctaaa ttcatatttt
     4141 taatttcttt ttcaatataa agttctaatt caaagggata ttcttttgaa gaattattga
     4201 acatatctat cggattaata atatactctt cttctaataa tctactattt gcttttttaa
     4261 gtgcctcttc aagtcttata ttttcttttc tactcttcaa tatctcctca tcttttatac
     4321 taagttgatt ttcaaaaaaa ttcctcttag ctatttcctg aataaattca gacatcatta
     4381 ataaattttc ttttaataca tataatctac ttttaggatt taatggaaat tcattgtaaa
     4441 ttttgtttat gtattttata tcaataccag aactacttga taattcagat aaatttttat
     4501 ctatataaat agacttatat actataaaat taccacattc tatatatcca actatatttt
     4561 cttctaatac tataggtatc tctaaactgg aaacaccata ctcacaatga tacacttttt
     4621 caaagttatc attatttatg cttttaacaa gttttttagt acacggtttt atatttttac
     4681 aaatatcgca aaatttattt tctttcttag tctcaaatat ttctttatac tttaagtcat
     4741 atacagatat tctaagcttc aatatattag atatttgatt tgcaagattt tcaattatgt
     4801 ttacattaac taactcctgt atattgtttt cagaaaatac tataggtatt tgtctcaaac
     4861 tcgaaaattt atgaggaaca taagtaatta atattactaa atcaatttta ccagtgttta
     4921 taatttcatg ttctgaatat ggtgggcaat aaactataga tgtttccttt atattgacct
     4981 ttttaccatc aattatttgt attccttctc cctgaatcac atataaaagc tgttcttcac
     5041 ttaaatgaaa atgcttttct tggcagtttc ccggaaaaaa tcttacaatt ccagcactaa
     5101 gtctattgaa ttgtgttttt gatggttcgt gtatccacat aacctctccc caatcaaatt
     5161 tttgtacttc attatttgac tcaataaaat ccaccataaa ctcacctcgt agtttttgtc
     5221 taaatatttt ttcttccctt cttatattaa aataatatca tcatcattaa ctttcattac
     5281 tataaaatca tcatactctt ttaatactcc tgtaatttta gttgcactta gtttactaca
     5341 attcagtttt ttaatatatt gataaattct ataattactt ttttattttg taaaatcagt
     5401 gttttcccaa aataattata tctataaatg aaagtatttt tactgcttac atcaatatat
     5461 gttatcataa ttttcctttt tattgcatat ataaataact gtatataaca ttgtccaata
     5521 ctatatagaa atacatctaa gaaagaatat tattaaattg ttccaattaa tattattttt
     5581 cttatagaaa taaaaaactg ttggattctt ttagaaaaat tattttttac ataccttttt
     5641 tgcttaaata gtctatcttc tcagctattt tgtatataca ctcttctagt tcatgatttt
     5701 attttaatat cttgcttata ttgctgaaat aattaaattc ttttatctat catattgtct
     5761 cttatatcac aaacatattg tttcttatat cacaaaaatg aaagcattct tatatcttca
     5821 atatataaac ctgctttttt taatcttgta ataaatatag gatactctat attctcttcc
     5881 tagaaataac taataccact tatttttcta tcatatagaa agtaataaat ctttttctta
     5941 ataaaattca atagtaagtg gaataaaatt ttatatgaat aagaacatta taaaaatact
     6001 ttatacaata gtcaataaaa gatattagct tcaaattgtg ttgaagttgt attatttaaa
     6061 gtggaaaagc aaataaaaaa gaaataatgg tataagtaga aaaatatact taaaacaagg
     6121 cgaagcctct cttgtatcta aatcaagtag agaattaaat ctaaaaaaga aaataaatat
     6181 aaaagatgac tcctgtacat tacaagaatc atcttatggt ttcataatca ctccatggtt
     6241 tttaactgtc tgatataaag gtctcagttc actcatagca tgaccacctt ttccgattgc
     6301 tgaccccgtc acttatggac aaaatgtcca taagtgatag tcctctctta aaaccctcta
     6361 aatagatata tctcaagcac ctcattgaaa ccagttgctg gaaacaaact gaagcgttct
     6421 ggaatagtaa aagaaattgc caccatatcc acgttactgt cctagttgtt actttgctaa
     6481 cttcggagcg atttcctcta acaatacgca gtcaaattct gcctttttgc taagaaatgg
     6541 cagatggtct gcatctggta taaaaaaaat ctgtttgtct ggcgccacta tttcatcaaa
     6601 aaatttcttc gctggaagat aggggctatt atagtcattt tctcccatga tgtagtatac
     6661 agggacctga tagtcaactc cataatttct tatgtcagct tcttccacta aaaaccgcaa
     6721 tacatcacct tgattgtcaa tcgcatttgg attgacaatg gccgtatttt ttaactctct
     6781 caatgaataa tatggggttg ccagtatact gattatattg cccaaatcca tatttataga
     6841 aagcccatac ttgctttggt atgttcttac tgtcataaga gctgccaaat agcttggacc
     6901 atattttgct ggcggatatg gtgcaatagc ttccagcgcc ttgatatctt tttgcttccc
     6961 tgcagctttc accatttcaa gtgtcttttc atagcccacg cgctcattgt ccaccatatt
     7021 aacagtctgc gcaatcccaa tgtacgcgct gtaatcctcc ggataggttt gcacagccat
     7081 agttcccagc actgttcccc agctatgacc tataaggata attttctcct tgttgaactc
     7141 ttgcttcaaa tatgctgtca cctcatggac gtcttgcaga acacgctccg cgctcatggt
     7201 ctgcaaaact gctgccggat cgttcgcaaa gtatgttttg cctacgtttc gctgatccca
     7261 gttcaccaca gtaaaatcat tttcccactc atactggtac agatgtaaaa atggcatcat
     7321 tgaattacca ggacccccat gaacccaaag gatgatgggg ttgtctgcgt tttgtccccg
     7381 gatatataac gcctgctgta tgccgccgat ctccaccatt tccatgcggt cgattccagg
     7441 agcttctatt ttatggcttg tacgtataat cgtgggggct atcagacgca aaccggcaaa
     7501 cgccagaaca aaaacagcaa ctagtatgca aagtgtgatt aatatcattt taagtacctt
     7561 ctttcatgaa tttttttagc catagatatc tcctctaaca ttaaaaaaag tatgttgcta
     7621 ttttagtttt gttactctac ctgtcccatt ggtttccttt cataaaaaat attaattgat
     7681 tctataatct catcttccag gatatcaact cctatttgtc tcataagaaa ctgtaagaat
     7741 tgaaaccgtt tacgaagtgt aggaaagtcc ccctgaaata catctgtatc acaccaaaag
     7801 ttaaagagca gcaaaattac ctctgcgcat tcatctggga actctgtgat gatgcttcta
     7861 tcctctatgc cttctcgtaa aacatttgct aatattggtg ctagtttttt caaattatcc
     7921 tgtgtaaatg ccagtatgat atgcggactt tctatcgcgc ttgtaatcat gttactagat
     7981 tcttttatca cctcatccgt taaatgccgc ctaactaaac ttctaagctt ctcttttgct
     8041 gtaagtccat gcatttcacc gagccattga tttactgtct ctattatctg ttcaaagcgc
     8101 ctttccatga ccacattaaa aatatcttct tttgaactga agtgatgaaa aattccgccc
     8161 tttgacattc ccgaagcatc aacaatattt tgcatacttg ttttgtcgta tcctttttca
     8221 gcaaacaact ttgcagaaat ggtaatgata ttttcaatag cttgctttgg attgttcttt
     8281 ctagtcatta tataactcct tcttattaaa aaccgactgt tggtttttat tatataagct
     8341 attcctgctt ctgtcaagta acattgtgtt tatggcaaaa caataaggtt tggtggttag
     8401 acaggtatta attagactaa tgcgactttc ccctagatgg aacccttggt aaatttgcaa
     8461 tctttaccgg ctttgattat atctgtaagc aaggcaggta tggccacgcc tgccctgttt
     8521 gaccctcgga tattcattcc tatccctcct ctccttagcc attacaccaa aacgccgctc
     8581 attgtctcca atggcggcgt tttaaagata tgatttctca tgctgctgaa atatgcaaaa
     8641 aatataagat gccctttatt atttttccta caatagaaaa gaaaagtatt gaagaatggg
     8701 ttaatattgg agcaaatatg ctttgttttg cacaagatac tacctttatc acttatgtta
     8761 tcaatcaatt attatctttt tataatgaga ttgtaccaat tcaaaaacaa cattaaatta
     8821 taaatctaat tttatattaa aagagactaa tattttatct atctctatta aggatatttt
     8881 cttatgtatc ataatattag tctctcttat tattatatac tgctatcatc attagttgtt
     8941 atttatacta tttttataat atacaaattt attcagctaa cgttttgcct aattctatac
     9001 actcatcttt tgcttcttca tttgggtctt ccattgctgt aattccttct ccaccaataa
     9061 ttgtagcacc agcattttgc atacgttctt cccagtctct catccattca caatttcccc
     9121 atccatatga accaaataat ccaatctgtt tacctgatac catagattct aattctgaaa
     9181 caaatggctc catatacccc tcttctagtt gctctgctcc catagatggg caacctaatg
     9241 caaatttatc ttcttctttt aaatcacttg gtttcagtaa gctcacatct aaaacttctg
     9301 gtgtcttacc ttttaacttc acaccttcag ccacaaaatt tgccattttt tcagtatttc
     9361 ctgttccact ccaataaaca atatatattt tactcatttt tacctcctgt agtatttttt
     9421 aattaatcaa tagttagtta tagctaacta acatctaaaa aacaaaagat ttctttatct
     9481 gaaatctctt tatttttcta aatatagaat atcatagttg atattgaaat tcaatactta
     9541 ttgataatat ttatcattta tattttatat tcattttata atatcaaaac actgtatcgt
     9601 atttctaatc tttcatagaa aaatttctaa cttatagtac ttttgcatct cttataaatc
     9661 ttttatatgt ataagtacat agaaaaacac accttttcca gatgtgctat ctataatatc
     9721 gtatatttat ttttcaattc taactagcta atatgtttat aaattttatc acttaatacc
     9781 tttatacatt gatgtaaaat cttacaccta agtaattttt attatttgtc tcgactctat
     9841 ataatatagc tattttatca tcaaatcaaa aattatcttt tactattatt cttgtattta
     9901 tagagattta aatataagta tccatttcct tgttccgttc taggtattcc aagcgctctc
     9961 gtacatttta ttaattgtgc atacagttca gcttcatcta aatctctttc aaactcctct
    10021 cttgcccatt ctttaattag tgctaatgag cctgatacgt atggtgcact catactagta
    10081 ccactcataa tagcaagttt attatccata taagttgata taatatttct tcctggagct
    10141 accaaatcta ttgtagtatt tgaattacta aacttttcaa ccaaatagtt ctcatttatt
    10201 gcacctactt ctattacctc agcataactg gctggataac tatactcact tgtactagaa
    10261 tcaccatctc cattattacc tgctgcacac actacagaaa tattattttt tactgcttgc
    10321 atgacagcat tttttaaatt cttatcatct ttgtttcccc caagagacat agatataata
    10381 tcaaccttgt tatttacagc aaagttaata gcattaatta tactttgata tgttccggta
    10441 ccatctttat ttaatgcttt tgctattaat aatttacaat ctggagctac tcccataact
    10501 tcattattat aattagatgc agctataata cccgccacat gagttccatg accattaaaa
    10561 tcctcatata tatttttatt tccattactg tcatcactaa aatttgcacc accaattatt
    10621 tttcctttta aaagaggatg agatatatca caacctgtat ctattatacc aactacaata
    10681 tttttaccag tataaccttc atcccacatt cccctagcat tcatttgttt tattccatat
    10741 gggaatttat tttttgcacc tcttagattt tcatttattt catatggaat tagtttcatt
    10801 cttttattca tcatatatcc tcctaaaaat tttattgctt ataaaaatca tgaattttat
    10861 tttataatag gtttataaat caaattaaaa cctatatcta cttatttata tttatgatat
    10921 attttttatt tttaggagtc atattttatt gtatataaaa taatatttag ataactatat
    10981 taaaaaatac atgtttgctt atatacaaaa cttactaaaa tatcttcaat atttttgtat
    11041 acaaacatta tattttttat ataaaaatct cataaaaatt ttgattatat tttcataagt
    11101 taacaaatgt gggtataata tgaatttaca aaattcctct gtttgtataa gtgctttacc
    11161 aatacactaa tatataatca cattgaagct atatttgtat ttatagtaga taatgtatca
    11221 aaaattggtt atgaatagta aaaataccag ttaagcatat tttcatgttt ctatttttaa
    11281 cattaaattt ccaatcttca tatgtatatt tttaacaaag gtgtttactt atttaaaaac
    11341 tctaaaactc tttcattaaa atcctgtgct tcttcatatg tagcgtgtcc caatccctca
    11401 tagataaata tttcgctttt tttaatcttt tctgctaaat gaaaagaagc attatttcca
    11461 acaattttat cattagcacc tcctataatt aaggttggac atgttatttt atttaattcg
    11521 gaaaaggcat tatgttctat gcaagaggtc gcttgaataa taaatcgttt aaaatccttt
    11581 ggtttaccta cttttcctaa aaaaggaata aataattggt atttttttaa atatctttca
    11641 gaataggatt tctttgctgt gtcaatcatt aaatcattgt aattctgctt cttcgccata
    11701 tcaatccaac tacaaataac attttggata gtatcatttt gctttgaaga agtaactgcc
    11761 aacacaagtt tctcaactaa ctcaggataa tcaattgcca gatattgagc tatcattcca
    11821 ccttgagaaa cacccattac ttctgctttc ataattccaa gttttttcat tatatctgct
    11881 tggtctttag ccatatccct tgtggaatat ttttctgtaa tttgattttt tctactaaat
    11941 acataaacct tataatcttt tgcaaattgc ttatatctaa aagcaaaagc aatcgcctgt
    12001 atttttccat gtaaaggaaa taaaccatct cctaatcctg gtaaaataat tagtgtcttc
    12061 ttaccactac caaattcaat ataattcact gtattacttc ctatcatcat ttgacaactt
    12121 tttgcattat aaaacatagt ctattcctcg cttttcctat tataattgtc taaataaatc
    12181 tttaaatttt tgaataccat actcatcaat tagaggaata tccatttttt ttaacatgaa
    12241 taataaaaaa tccaacctat tacatacttc actgtattca cgtttaaata atacagggtc
    12301 aagtaaaata tcaatactaa aaacgagcat ttcagctaat tcctctggat attcacaaga
    12361 aaattcttta ttttcaacac cttgtttaat tatcttagca atattgggtg caactacatt
    12421 gttgagatta cgaacttcct ctattaaagc gaatgggatt ttttctaacc agctacaatg
    12481 taccattttt ctacgtgtgt aatcattcgc actatgaaca accaattcta ttattttttc
    12541 atttgctgta agggtgtcat cagcaacaag atgctctaaa aaattattca tttgtgagta
    12601 aagttctttt gtgacacttc tcagtatatc ttctttagtt ttaaagtgat gatacattgc
    12661 acctctagat agaccagata aattgataat atcttgtgta gatgttgaat catatccttt
    12721 agacgaaaat agtgaaaatg ctgattggat aattttttct ttactatttt tacttttttc
    12781 ttctctattc atatttccct cctaaaaaca gactgtctgt ttgtttttta ttatacattt
    12841 taatatttat tatgtcaaga attaactgac tttcaatttc ttcatagttc agatggaacg
    12901 aaaagcattc cacatcaaac ttttaaaaag ttgtattacc tcaacaaggt ctaaaagata
    12961 catctctatg ctgtactcgt attccttata atagagatgt attgttttca aagataatca
    13021 agattttgct gtgtttttca tacaaaataa aaaggatacc tcattagtgc tataacacct
    13081 aagatatcca attaatattt tcttaacttt ttctaattta cataaatata gtctactatt
    13141 ttaaaactgc tcctgtattt gctgatgtta ccagtttagc atatctactt aagtatccat
    13201 gctttatttt cggttctaaa ggtttaaatt ttaattttct attttctatt tcaacttcat
    13261 ctacttttaa ctctaatttt ttgtctggta tgtttataga aattatatct ccttcttcaa
    13321 ctaacccgat taaaccacct tccatagctt ctggagaaat atggcctata gatgctcctc
    13381 tagttgctcc tgaaaaacga ccatcagtaa gaagtgctac atgcttatca agtcccattc
    13441 ctgcaactgc tgatgtagga gatagcattt ctttcattcc tggaccaccc tttggacctt
    13501 catatcttat aactataaca tcacctttgt ttattttttt accaaaaata gcatttacag
    13561 cttcttcttc tgaattaaaa actcttgctg gtccttcatg aactaacatt tcttctgcaa
    13621 ctgctgactt ttttacaaca gctccattta gagcaagatt tcctttcaat attgcaagcc
    13681 caccttggtt actatatgga ttctttaatg tatgtattac ttcttcattt tctatttcac
    13741 aatttcttat attttcccct atagtcttgc ctgttacggt tttgcaatct aaatttattc
    13801 catttatctt tgaaagttcg ttcattatag ctggtattcc tcctgccata tgtaaatctt
    13861 caatatgatg ttttccactt ggacttaatt ttgttaaaca aggagttttt tcacttattt
    13921 catcaaaaaa atttaagtta agctctattc ctgattcata agctattgca ggtaagtgaa
    13981 gtactgtatt tgtagaacca gccattgcca tatccacagc tatagcattt ttaaaagcat
    14041 ctattgttaa aatatctcta ggttttatgt cgttcttaag taactccata acatacatac
    14101 ctgcatattt tgctatcctt tttctttctc cagaatgtga cgcagcagta ccattatatg
    14161 gtatacccat gcctaaagct tctgttaaac aattcatgct atttgctgtg aaaagaccag
    14221 aacatgaacc acatccagga caagagttca tggctaacgc ttctaattct tcttcactta
    14281 ctgttccatc tttacatgct ccaacaccct ccattgcaga gttaaaatca tatacttttc
    14341 catttttttt acctggaagc ataggccctc cactcacaac aatacttggt atattaagtc
    14401 ttgcagcagc cattaacata cctggcacta tcttgtcaca attaggtata agtaccaaag
    14461 catcaaaacc atgtgccata gccatagctt ctattgaatc tgctattaat tctcttgaag
    14521 ccagggaata attcattcca acatgcccca tagctatacc atcacatacc cctatagcag
    14581 gaaattctaa tggcaaacca ccactcattc ttactccatt ttttgcagct tctgctattt
    14641 catcaagatg cagatgacca ggaatcacct cattttgtgc atttactata cctattaatg
    14701 gtctttcaat ttcttcttta gtaagaccca ttccatacat taacgctctc tttggagctc
    14761 cttctattcc tttttttata tcacttctca taatattacc tctttcttac ttttttaaat
    14821 tttcataata ttattataat atatttttct attaattaat tacgaaaatt gtaaaaaaat
    14881 attagcatat actaatgaaa atttattacg attttttatc aatatcttac acaattgtat
    14941 tatataatat tatcttttca atatatttta taaactaata tattttacaa attgttgagt
    15001 aatattttat gatataaatc agaagaggca cttctataat agaaagtgct caactatgaa
    15061 taagattaat aatatatttg ccttagatat atagactttt ataaatatta aagattaatc
    15121 aaatctgatg tttgaaactt tatcccaatt aatcttcctt gaatagtctt ctggatgtga
    15181 taatctaact atatgagttg aattatcata gctgtaataa attgtagtag taccatcaac
    15241 tggattcttt ttgtatcctt gatacacagc actatttggt actttctttt caacaaagct
    15301 atatgcagat gaagtatcaa tagtttctat tttattagga aatataaaca tataaaaagc
    15361 tactactata aaaatacata tgcatgtaat actataccat ttaatccatt tcataaaatt
    15421 cctcctactt taccaaaata tactattatt atttccatat atttataata tttatgcata
    15481 cgataaaatt tttatatccc taactatata attgtagaaa ctttgattat atatattttt
    15541 taatcttaat aatatatttt tataaattaa taaattttta agattttatt aaaagatttt
    15601 taaaacttac agtttaatat aaagatagta cttataaaac taaaaacata aatttgaaag
    15661 gggacaaaat aaaatgatat ggacatttta ttcatttatt tgcgttatat taccatgctt
    15721 aatataccaa atagtcgtta taaaacgaaa aaatttgaaa gttgaaaaga atgtaatgat
    15781 acatttagta tgggtatata tttttttatt atatatctat ctagcactta gtaaagctgg
    15841 aattggtagc atatgggata taggaaggta tagtgggctt tttagaattg atgaaataaa
    15901 tctaatacct tttgactcag ttggcatctt aacatatatt ttaaatataa ttatgtttat
    15961 gcctttagga tttttactac ctttaatttg gaaaaatttt agaaatatta tcaatgtttc
    16021 attaactgga ttaggttttt cattagcaat tgaactttgt caattgttta acttaagagc
    16081 tacagatatt gatgatttaa tgatgaacac attaggtgct gttttaggat attttatatg
    16141 ggtaggtgta aataatttat ttaatcttat aaagaaaaaa gatattttcc catctatata
    16201 taaaaatatt attcaagatg aaattgctat tacaattgat gatgacataa gcgaaaaaat
    16261 tacctctctt tacaaaaatg aagctattat atatttaata cttgctgttt taggagaatt
    16321 tttattgttt aattggtcca ttatacctta ttaaataatt tattgataaa acaagtgtac
    16381 ttcgatattt acaaatatgt aaagccctct ttcataccac aaaagaaagt gggctttagt
    16441 tattaaatta aaatgcacac tcactattta gctggcatct gaaatatttt attaacattg
    16501 tatctgactt tatttgatgt tatataatca tattttgttc cattttcaat gaagttttgt
    16561 atattgtcca acacttgtat agctcttgta ttattttca
//
LOCUS       DAGQVA010000089        16371 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.089, whole genome shotgun sequence.
ACCESSION   DAGQVA010000089 DAGQVA010000000
VERSION     DAGQVA010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16371
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.089"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     regulatory      complement(155..250)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            459..836
                     /locus_tag="MIV85_003179"
     CDS             459..836
                     /locus_tag="MIV85_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2962500.1"
                     /translation="MKEEILVEKLLRAELIVMEYLWKKDSLVTKKEIVKEMRQVYRWH
                     KSTIKILLKRLVDKGYLARDIIKFQSHYKIIIDNKEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKSISKEKLDALEEYYRNLEE"
     gene            946..1329
                     /locus_tag="MIV85_003180"
     CDS             946..1329
                     /locus_tag="MIV85_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2962501.1"
                     /translation="MKISKLPEAELKVMRYIWEANDVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNAMVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            1514..2098
                     /locus_tag="MIV85_003181"
                     /pseudo
     CDS             1514..2098
                     /locus_tag="MIV85_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            2124..2537
                     /locus_tag="MIV85_003182"
     CDS             2124..2537
                     /locus_tag="MIV85_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2962502.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            2541..3284
                     /locus_tag="MIV85_003183"
     CDS             2541..3284
                     /locus_tag="MIV85_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBY2962503.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            3284..3754
                     /locus_tag="MIV85_003184"
     CDS             3284..3754
                     /locus_tag="MIV85_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2962504.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            3771..4529
                     /locus_tag="MIV85_003185"
     CDS             3771..4529
                     /locus_tag="MIV85_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2962505.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            4513..5355
                     /locus_tag="MIV85_003186"
     CDS             4513..5355
                     /locus_tag="MIV85_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBY2962506.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(5515..6420)
                     /locus_tag="MIV85_003187"
     CDS             complement(5515..6420)
                     /locus_tag="MIV85_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBY2962507.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSTHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            6782..7516
                     /locus_tag="MIV85_003188"
     CDS             6782..7516
                     /locus_tag="MIV85_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962508.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            7727..8908
                     /locus_tag="MIV85_003189"
     CDS             7727..8908
                     /locus_tag="MIV85_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBY2962509.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKFSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            8892..9464
                     /gene="mobB"
                     /locus_tag="MIV85_003190"
     CDS             8892..9464
                     /gene="mobB"
                     /locus_tag="MIV85_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBY2962510.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            9583..9858
                     /locus_tag="MIV85_003191"
     CDS             9583..9858
                     /locus_tag="MIV85_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2962511.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            10113..11813
                     /locus_tag="MIV85_003192"
     CDS             10113..11813
                     /locus_tag="MIV85_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962512.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            12176..13363
                     /locus_tag="MIV85_003193"
     CDS             12176..13363
                     /locus_tag="MIV85_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962513.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            13423..14586
                     /locus_tag="MIV85_003194"
     CDS             13423..14586
                     /locus_tag="MIV85_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2962514.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            14737..15540
                     /gene="zupT"
                     /locus_tag="MIV85_003195"
     CDS             14737..15540
                     /gene="zupT"
                     /locus_tag="MIV85_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBY2962515.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            15636..16196
                     /locus_tag="MIV85_003196"
     CDS             15636..16196
                     /locus_tag="MIV85_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBY2962516.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
BASE COUNT         6369 a         1705 c         2915 g         5382 t
ORIGIN      
        1 tttttgtttt tgatacgaat ttacatcttt attatatcgc attttaagaa aaaataaaac
       61 tgtgaatgct agaaatatat tttattttat ctctaagtat atatattatt agccacctaa
      121 aaaactttca taaaaacaaa aagaacaata tctttttggc aactggctgg cataatttat
      181 aagaatttta taaatcttag tccctatagc tttgcgtcac taaatttctc tagttttgcc
      241 gatttagttt tattctacaa ctaaaataat acaatagaat tagttattat tcaacaggat
      301 agtttgaaaa ttgaataatt ctatagatat gaaagttatt tttcttctaa gaaaacaaac
      361 taaaacagta gaatatttgg taaaaattac ctatagtttt tgtcttaaaa agctcttatt
      421 attaacttga actagaacaa tcgaaggagt gacataagtt gaaagaagaa atattagtag
      481 aaaaattatt aagagcagaa ttaatagtaa tggagtattt atggaaaaaa gattctctag
      541 tgactaaaaa agaaattgta aaagaaatga gacaggttta tagatggcat aaaagtacaa
      601 taaaaatact actaaaaagg ctagttgaca aaggttattt ggccagagat attataaagt
      661 ttcaatctca ttataaaata ataatagata acaaagaata ttatgctttt aagaaaaaag
      721 tgttaaaatc tagcaaaagc agaaaaataa tgcgttctct tactactaca cataagtcta
      781 taagtaaaga aaaactagac gcattagaag aatattatag aaatttagaa gaataatttc
      841 gagatggaaa aaattggatg gtaatattta gtgtgattct cttgtttgga aaactttatt
      901 gagatagaat ttaacatata cataattcga taaaggggtg tgactatgaa aattagtaaa
      961 ttaccagaag cagaattaaa agttatgaga tatatttggg aagctaacga tgtattaacg
     1021 tctagggaat tagttgccgc aatggaagaa aaatacgaat ggaatgaatc aactacattc
     1081 acagttttaa aaaggttaga gcgaagggag tttttaagta cagagaaaat aggtaaactt
     1141 acacactata atgcaatggt aaaagagaaa aaatatctaa gatttgaaac aaaggaattt
     1201 ttgaagaaca tacataagaa ttcaatttca agtttaatat cagcgttaca tagtaaagat
     1261 gatgaagtgg atgaagataa attaattgaa ctcgaagaac attttaaaaa tttaaaagag
     1321 aaagaataaa taaagattat tttaggtggc aaattatttt tgccaccttt tttgccacca
     1381 tgacagttta ataaaataaa atacaaataa agaaatataa ataaaataga ataaagaaat
     1441 tgttttagat aggttgtaaa taaatgtact cataaaaaca taaataaata taaataaaca
     1501 taaataaaat ataagaattt ctgtgagaaa tgcacttaat gaacttgtaa aagaagatat
     1561 attatgtaaa aaacgtggta aagggactta tgtaacaata ccagagagaa tagaagcaac
     1621 atgtgcagga aatagtttta ctaattcttg tcatcgtatt aatgcaaaac caagtaccaa
     1681 aataatctct gttttaataa aaaaagcaga taagcaagta gctgaagctt taagtattga
     1741 actagaagag aaggtaatat gtattaaaag acttagatta atagatgaag tacctgttat
     1801 ttttgaagtt gactatttta gaatagatta catgttttta ttaaaagaag aattagaaga
     1861 taaatcttta atggaggtta tatctaataa tataagcaca ttacctaaac gagtagaaaa
     1921 tatatttgaa gtaaaacatt caaacaaaga atattctgac catcttaaat gtgcaagtaa
     1981 tatgccacta ttgaaagtaa gacaatcggt gtatacagaa aataatgatg tcttatatta
     2041 caatgagcaa tttataagaa gtgataagta caaatatgca gtatcagcag aaatataatc
     2101 tataatttag taggaggatg agtatgaaaa agataatatt agcatctcat ggagactttt
     2161 caaaagggct tttaaatgca gtaaaaatga tagtaggaga tttagcagat tgtgtcagtt
     2221 cgtatggttt gtaccctgga caaagtgctt cagattttgc tttagaatta gaaaaaacaa
     2281 tatcagaaga taaagaatgt gaatatataa ttttatctga cttatatgga gcaagtgtat
     2341 gtacagcaat gttaagatta actaatctac ataatgttag gttattttct ggaatgaatt
     2401 tgaatatggt attagaactt cttacaaggt tttctgatga attaaccgtt gaagatatag
     2461 accaattagt ggaagaatct agaagaggaa tacaaagcgt gacattacaa attaaagaag
     2521 aagaagaggt attttagttt atgaaaaaaa agggaatatt atcagtattt aaaagtaaaa
     2581 aaccaattat agcaatgata cacttaaaag gagatactcc agaagatatc tttgaaagag
     2641 ctaaaaaaga gattacaatc tttgaagaaa atggtgtaga tggaataatg ttagaaaatt
     2701 actatggtaa ttattatgat ttagaaagaa tacttgaata tgtatcaaaa gctaatttat
     2761 caataccata tggagtaaac tgtttaaatg ttgatactat gggatttgaa ctggcaacaa
     2821 aatataatgc tagttatata caggttgatt ctgtagtagg tcatgttaaa cctagagatg
     2881 aagctacttt agaagagttt tttaaattac aacgttcaaa atgcccagcg tatttaattg
     2941 gaggcgtacg ttttaaatat cagccagtat tatcagaaaa tgatgttgaa gaagatttaa
     3001 aaataggaat gacaagatgt gatgctatag cagttacaga aaatgctaca ggtcaagaaa
     3061 catcaatgga aaaaatagaa ctgtttcgta aaaatttagg agacttccca ttggttatag
     3121 ctgctggagt tacattagaa aatgcaaaaa aacagcttaa attaggagat atggcaataa
     3181 taggaagtta ctttaaagat aattacaaag attttgggga tgttagtgta gaacacgtaa
     3241 aaacattcat ggatgaaatc aaaaaaatta gggaggaatt ataatgatta aattagtaag
     3301 agtagaccac agacttatac atggacaagt agcatttaca tggacaaagt ttttaagcac
     3361 agactgtata ttgatagcaa gtgatgactt attaaaagat gaattgagaa tggcaggact
     3421 taaaatggct aaaccatcta atgttaagtt agtaatgaaa agcatagcag attctataaa
     3481 agcacttaac tcaggtgtta ctgataaata caacttattg atactttgtg aatctgtaga
     3541 agatgtttat agacttgcta aagaggtaaa agctattaaa tctataaacc ttggtggaac
     3601 aaaatcagat gataatcgtg aaaatatatc taaagcagtg catgtatcaa aagatgatat
     3661 aaagatgatt aaagagttag attcagaagg cgtaaatgta tttgtacaat tagttcctga
     3721 tgatgatgct acaaatgtaa tgaaattaat ataattttag ggggatgaaa atggaattta
     3781 cacaagttat tttgataact ctaattgcat tctttgcata tatgcatagt tttgtaggtt
     3841 ctacaatgca taatagacct atagttgttg caccacttgt tggtttagca ctaggtaatc
     3901 ttcatacagg tatagtaata ggttcaacat tagaattagt atttatgggt gcatttcctg
     3961 ttggggcaag taatcctcct gattttgtgt ctggttctat tattgccaca gcgtttgtaa
     4021 tattaacggg tcaagatgta tcagcagcag ttgtacttgc agttcctata gcaactctag
     4081 tattgcttat agataacttc ttaatgacag tagtacttac atggggagct catattgctg
     4141 accgttatgc agaagagggg aatattgaag gcgtagaacg tgtgcaatta ttatttggta
     4201 taggaaataa attaatatta gcaataatag taggtatagg attttcatta ggtgttccag
     4261 taatagaaaa aatactttca tttataccat catatgtaac tcatggaatg gatgttgcag
     4321 caggcgtgat tccagcaata ggttttgcca tgttagctag aatgatgctt aataagaaaa
     4381 cagtagcatt tttattatta ggatttatat tggttgctta cctaaacata acagtaacag
     4441 gagttgcatt gtttggatta gcaatagctt taatatatgt taactttgta ggagagaagg
     4501 aggtaatagt agatgacaac gagttctaag aagttagaga caatttcacc agatagtaaa
     4561 ataacgagga aagacttttg gaaatgtttt agaaggtcat tgacattaga ttcatcttgg
     4621 aactacgaac gtatgcaaaa tatagcatat gcatacatga tggcaccaat aatccgtaga
     4681 ttatataaag atgataaaga aaagaaatct aaggctttaa aaagacattt agaatttatg
     4741 tcagttactc ctcatataag tactcttttg gtaggtatat ctggagctat ggaagaagaa
     4801 aatgcaaaga ataaagaatt tgatgctaat agtataaatg ctgttaaatc aagtttaatg
     4861 ggtccagttt ctgggatagg agattcattt ttctggggaa cattaaagct tatagcagct
     4921 ggggttggta tagctttagc ttctcagggt aacataatgg gaccgatttt attcctttta
     4981 ataataaatg ttcctcattt tattatacgc tatatatgtc tagataaagg atttaagtat
     5041 ggaactcaat tctttaaaga tgtgagtggt tcaagtatag tttcaaaagt tatggaagca
     5101 gcttcaatgt tagggcttat ggtaattgga ggtatgactg catctaatgt aatgttaaaa
     5161 cttagtgtta atgtaggtag tggagaatgg gcagagccta ttcaaactta cttagaccaa
     5221 ataatgccat gtatgcttcc agctatgata ttcggtatta tgtattggtt attaggaaaa
     5281 aaggtaaaga caactacgat attaatttca gttatgatta tttgtatagt attggctgct
     5341 attggagtag tataaataaa aaaatcccaa gttcatttga acgagggatt ttttgactaa
     5401 attaaataaa aaagaaagat ggttcataat aatttataag catttatgtg atagttataa
     5461 ttagcttatt aattagttat aaactcaaaa ttaagcacta ctttattaaa gttattatat
     5521 tataatttcg aaatactcac ataatctgtt tagaaattta tcttctaatg gggaaaaagt
     5581 tttcttttta gagtaaatga agaaaaactt tctagtaaaa tcaacatcct ttattttata
     5641 acattttatt ttacctgcat tgagataatc gatagctgaa atgtacgata taaaggacac
     5701 tccaagacct aatctaacca tttccttaat agcctcattt gattctacat gagcgattac
     5761 atttaattta cttactggaa agttattttt actaagtgtg tttagtatta agtttcttgt
     5821 acctgaccct tcttttctca taataaaatt tagataagcc aattctccta tatcgataca
     5881 attattttta ttatcaattt taaaatctga aggagtgata agaacaagtt catcatctaa
     5941 taagtctagg tactctattt gaggattatt gattttagaa ccaactaatc caaagcttat
     6001 tcgttcattt aaaatttctg atatagcata ttgagaatca taatggctta tggaaaattt
     6061 tacatctgga taactcatag aaaaactctt cataaaatca ggtaaaatat aagtttcagg
     6121 tatggaacta catgctatat ctataatacc ttctattttt cctgaatatt cttttatatc
     6181 ataaattgca cgtttgcaat tattcaatat atatatagca tgttcataaa gaatttcacc
     6241 agattttgtg agtgtaataa ctttgttgct tctatttata agaacagttt ctagctctct
     6301 ctctaaattc tgtatgtgtg tgcttacagt aggttgagtt aaaaaaagtt ctcttgcagc
     6361 ctttgaaaaa ctctgatgtt ttgcaacagc aacaaatact tcaagttgtt taaaatccat
     6421 tatttaatcc tccttaaatt atctaaaact attataacat atttgataaa ttaatagtca
     6481 aaggtgattt ttaaaataga aaacctttaa atattcatgg agtttttgat tgtttaggaa
     6541 taatttggta taatgttgta aggtacttac aataaaaata tcgtaaattg aattttcaaa
     6601 attcaacttt aaagtgtttt ttattacaga aaaattacaa ttagcttctt aatcttatta
     6661 aattcaaata aatattatat aattatttta taatataata aatataatta ttgaaaaaag
     6721 agataactgt aaattgagat atagataaat actataaaat ttaagaaagg aggattgatt
     6781 tatgaagtta aaaaggtcat tagtttgtgt aactatttta ggtattatac ttgttggatg
     6841 tcataaagaa aatactaaag agaaaaatca agtagcaagt aaagcaacac agcaaaaaac
     6901 tatgacaaaa gttcaaaatg atgttaatga aattatgaat aaagattata agtacattat
     6961 aaagaatatg ggtatacctt ataatacatt ttattatata aaacctaaag ttttaaaaga
     7021 atcaaataca atgcaagata taaatacatc aagttatatg acattagttt atccaaaata
     7081 tactggaaat gatgaactag atggaagtgc tttatatgtt gatattaacg aaaataaagt
     7141 tgtcaatgtt gaaaccaatt ctttctcatc acaaggtata tcagtcattg atgctgaatc
     7201 tagtatagtg attgaaaaaa gtgaccatga aaaatcggct gtatcactag aaaattttag
     7261 acatattgac ctgggagagt atgttggtgt tgaagattcc agaataaatg aaattgtagg
     7321 agatgcgaat tatgatttaa cagcatataa tcatgaaggc agtaaagtag ttaagagtta
     7381 tagattgaaa gaagataaca aaatattaaa aaaagaggta cttacaataa gtattgtgga
     7441 taacaaaata aaatctataa aaactattga aagtgataaa attgtaaaaa taataaaagg
     7501 aactttatta gaataaaata ttctaaagca tatgatgctg tttcaagata gaaggaaatt
     7561 tctagctggg aacagttttt ttattagatt tataaaattt gaactgcact tatagataac
     7621 tattagttat aattaaatat aagataaaag tatttccaac ttttataatc tataatatat
     7681 tacatagaaa tatcttaaat aaaaaatata ttggggagta tttaaaatga tagaattaga
     7741 agatgccata aaaattattg aaaaaaatgt tttaccaata aacagggtca agatagtaaa
     7801 tcttatagat gcagtaaata aggtagttgc agaagatata tattcaacaa ttgatagtcc
     7861 tccatttgat aggtcaccct atgatggtta tgcatataat gcaaattctg aaaatagaaa
     7921 tttaaaggtt atagggactt tgtatgcagg agatgtattt aatagggtat taaataaaaa
     7981 tgaagcagtg aagataatga ctggtggaaa gataccacag ggtgcaaatt gtgtaataaa
     8041 aaaagaagat gtaacagtta taggtgatat gataacttta aatataaaat taaaggaata
     8101 cgataattac atatttaagg gtgaggatat aaaaaagggg caattgatta ttaataaaaa
     8161 tcagaatata ggatatgatg gtattggagt attagcaagt cttggaatat ccaaagtaac
     8221 tgtttatgat gatttaaaag ttggaatttt gaatacaggt acagaactac aagatataaa
     8281 tgagacttta gagaatggta aaatatacga tagtaataga tataccttat attcaagatt
     8341 attaaaactt ggaatacaag cagatacaat atgcaattgt tctgatgata tattggagtt
     8401 agaaaaaaag gtaaagaata tgttacagag tgtagatttt ttaattacca caggtggtgt
     8461 ttctgttgga gataaagatt taattccaga tgtattcaaa aaaatagggg caacagaatt
     8521 attttggaag ataaacatta aacctggtgg agcttgttat gtaggtacat tgggagaaaa
     8581 gctattattt ggtctttctg gtaatccaca tgcagcaata gtggtatttg ataatgtgat
     8641 agttcctgtt attgagtatt taacatataa gaagggaaca catcatataa aagctatatt
     8701 taaaggagaa tttaataaat tttcaaataa agatagattt gtaagtggaa aactatatac
     8761 aagtgaaggt aaattgtatg tagagctaaa tgataagaaa gatgcaaaag ctagactatc
     8821 tgcaactcta agaagtaatt gtatgattaa gattaaaaag aatgagacaa taaaagaaaa
     8881 tcaattagtg gatgttgtta ttagatagtt ttatgaaagg acacaatttt atgtataata
     8941 tattgtcagt tgtctcatat tcaggagtag gtaaaactac gttgattgaa ggcataataa
     9001 aagaattaaa taaaaaaggg tatcgtgttg gagttattaa acatacctgt catgattttg
     9061 atatggatga ggaaggaaaa gatacttata aacatagaaa atctggggcg agaaaagtct
     9121 gtataatatc agataaacga gtagcatata ttgaagaact aaaagagaag aatccattat
     9181 ataaaatgat tcaattatat gaagatatgg acttgattat catagaagga tataaaaatt
     9241 atagatttaa aagactggaa gtaactagaa aaggtaagta tgaggatatt ttatctaata
     9301 agtctgattt gataggtatt gttagtgata tagaatataa attgaatatt gaacagttta
     9361 atttaaatga ttataaaaat atatcaaagt acatagagtc ttgtataaaa aatgaaattt
     9421 taagtataag caatgttgaa ataaaaaaca tattaaaaga ataattttaa gatgttcttc
     9481 ttatataaaa tgatataatt atttatataa ataaagatat aagaaattta tcaattttat
     9541 tttgagttat aaaatattaa agaaattgta ggaggacaat atatgaaaaa aatattagta
     9601 gcctgtggag caggaatcgc aacatcaaca atagtttgtg acagagtaga aagattggtt
     9661 aaagaaaata atatacaagc agaagttgag caatgtaaaa ttgctgaatg ttcaacaaaa
     9721 caagaaggtg ctgatttaat cgtatctact actatactac caacaactta tgatatacct
     9781 acaataaagg caacaggata tataacaggt ataaatacaa cagcattaga taaaaagata
     9841 ttaaatgcat tgaagtagtt ttgtatttat aaaaaaaatt tagtattaaa tatagagttg
     9901 tatctttata aaattttaaa tatagagata tagctctttt tatgttgttt caagtataca
     9961 actatatgat ataaatcttc aattttatga aaaagattgt tattactttg taagtttata
    10021 aaagatttaa agttattgtt atgttatact aatttatggg tattttttag aagtactaat
    10081 agaagtacta ataaaggagg gatttaatac ttatgataaa acaatttgtc aaatattata
    10141 agccatataa gaaaattttt acactagacc ttatagcagc ttttctattt tccttatgtg
    10201 atttagttta tcctatgata actagaaata taatggatga cgttgttcca aataaaaact
    10261 taagaatgtt agtagttttt gcagtagcac ttatacttat atttatagca aaagcagggc
    10321 ttaactattt tatgcagtat tggggacatg ttattggtgt agatatgcaa gctgatatga
    10381 gaaatgaggt atttacacac ttacaaagac ttccaaatac gtattttgat aataacaaat
    10441 ctggagtaac tatgtctaga atagtaaatg atttaatgga tataacagaa cttgcacatc
    10501 atgggcctga agatttattc atttctatag taatgttggt tggttcattc tttatactta
    10561 tagatataaa tattcctctt acgcttataa tatttgctat attaccgttt ataatttggt
    10621 ttgcaatagc taaaaaagat aagatgaata ttgcttttat gaagagtaga gttactatag
    10681 gtgatgtaaa tgctacttta gaaaatagta tagcaggtat gaaggtaact aagtcttttt
    10741 gtactgagaa agaagagtta aataagtttg taagaagcaa taaattattt agaagagcaa
    10801 gacaagattc ttataaggta atggcagaat attactctgg tatgaattta tacatggata
    10861 tcttagagtg ggtagttgta atagctggtg gttattttac ttatatagga aagattactt
    10921 tgggtgattt tgctgcttat atactatatg taaaaatgtt tatacaacct atgaaaaaat
    10981 taataaactt tacagagcaa tatcaaaatg gtatgacagg ttttaaaaga ttcatagaga
    11041 taatggaaca agaccatcaa aaagaagcta aaaatcctat tgaacttgaa aatgtaaaag
    11101 gtgacattga gatagaaaat atatctttca catatgaaga taagactcaa gttttggata
    11161 atttaagttt atctataaaa gctggtaaga ctatagcatt agttggacct tctggaggag
    11221 gaaagactac attatgtaat ttattgccaa gattttatga atttgataag ggtgatataa
    11281 aaattgatgg aaagagtata aaagatgtta gtttaaaatc attgagaaaa aatataggta
    11341 tagttcaaca agatgtattt ttatttacag gaactataag agataatatt ctttgtggga
    11401 accctaatgc cacagatgaa gaaatgatag ctgctgctaa aaaagctaga atacatgact
    11461 ttgtagagac tttgccagat ggatatgata cttatatagg agaaagaggc gtaaaattat
    11521 caggtgggca aaaacaaaga atttcaattt caagaatctt tttaaagaat cctccaataa
    11581 taatattgga tgaggctaca tctgctttag acaatgtaac agaaagagaa attcaagagt
    11641 ctttagagga attaagtaaa gatagaacaa atttagttgt tgcacataga ttgactacta
    11701 taaaaaatgc tgatgaaatc atagtattga cggataaagg aattgaagaa agaggtactc
    11761 atgaagagct agtaaacaaa aatggagtat atagtaggtt acacaataac tagtatacaa
    11821 attttacacc atagctaaca tacacattaa acttacaaac ataggatata ttaagattca
    11881 taaagacaat tcattttata tttataagat gttttatgaa taaaatgtat cctatgtttt
    11941 attttttgca aattacattt aattctcttt gtaagaatag agttaaatag ccaatggtcg
    12001 ggataacgtt tttacaaaaa gaataattta gaaaactaac tttaatttat ggaatttatc
    12061 gaattttatg aaaaaaatcg aattttgact tgaaatgttt ttcaaaagta gtaaaataat
    12121 ggataactat acatacattt tataaaaata tatttattat gaggggggat tttgtatgga
    12181 ggcaataaca gctttttgtc tagttttagt atcactgacg ataggagata tagtttcagc
    12241 aaaaactaaa gcttttgttc cgtcggtttt tgtatcagca attatattta tagtaggatt
    12301 ttggactttt ttcccagaaa atattgtgga cttagccgct ttaggaacac cattagctca
    12361 attaggtatg cttttgttaa taactcatat gggaactatg atgagtatta aggaattagc
    12421 aggtcaatgg aaaacaatag taatagcctt ggcaggaata gtaggaatat gtgtaggtgc
    12481 tttggcatta gggacagtag tatttggatg ggatacagca gtaatagcta cacctcctct
    12541 tactggaggg ctagttgcat ctataatgat ggcagatgct gctacagcaa aaggtcttgc
    12601 aagtttatca gtacttgcaa ttttgatgta tgttgcacaa ggatttgcgg gttatcctat
    12661 tacagcatta atgcttaaaa aagaaggaaa aagactttta tcagacttta gaagtggaaa
    12721 agtaactgta aatacagatg aagaaaaagt taaggattta cctgaacaaa aaagcagatt
    12781 taagataata ccagacttac cagaaaaata tgatacgaca tatatgataa tacttagatt
    12841 aggatttgta gcatggttag cagtacaatt tacaaatctt acaaatgaag ttgtatcaag
    12901 atatgttata tgtttaatat ttggtgtaat agcatcagaa cttggaatag ttgatagaaa
    12961 accacttaat aaatctggtt catttggatg gttaatgaca tcattgatgg cttttatatt
    13021 tgcagggtta gcaaaagcta caccagcaat gcttgttgaa atggcagttc ctcttgtagg
    13081 aatcataata tttggtgtaa taggtatggg aatattctct attatagtag gtaagctttt
    13141 aggtgaaagt aaagaaatgg ctttttcagt ttcgcttaca tcactttatg gttttccacc
    13201 aaactatata ttaactgaag aggcagtaaa ggctttggct gaaacaccag aagaaaaaga
    13261 atttttaatg gataagatgc ttccaaagat gcttgttgga ggatttacta cagttacaat
    13321 agcttctgta gtaatagcag gtatctttgt aaatctaata tagtatttaa gtgataaaaa
    13381 gtattttaaa taagaagaat gtgtactact tggaggtatg gaatggatat taaagaaata
    13441 acaaagagtt ataaagacta tgtaattaag cttagaaggg aatttcatga aaatcctgag
    13501 aaaagtatgg aagaagtgag aacatcaaag agagttaaag aagaacttga taaaataggg
    13561 ataccatatg tatcagctgg aggtacaggt gtaattgcaa ctataaaagg agctaatcca
    13621 ggaaagactg tagcacttag gggtgatatg gatgctctac aagttgttga atgcactgat
    13681 gtagaataca aatctaaaaa tgaaggactt atgcatgctt gtggtcatga tggtcacaca
    13741 tcaatgcttc taggggcagc aaaagtgtta aatgatatta aggatagtat caatggaact
    13801 gtaaaattat tttttcagcc aggagaagaa gttggtaaag gtgcaagagc tatgattcaa
    13861 gatggtgcta tggaaggtgt agatagtgtg tttggaatac atctttggac tgatgtagaa
    13921 tctgggacca tatcggtaga agaaggacca agaatggctt ctgctgattt ctttaaaatt
    13981 actgtaaaag gtagaggtgg tcatggttca cttcctcatc aaggtgttga tgcagtgctt
    14041 gcaagttcag caatagttat gaatctacaa tctatggtta gtagagaagt aagtcctctg
    14101 gaaccattag ttgtgagtgt tggagtttta aattctggaa ctagatttaa cgtaattgcg
    14161 agtgaagctg tcttagaagg tacaataagg ctatttaatc cagagcttag aaagcaaatt
    14221 cctggaattt tagaacgtat agcaaaatct acagcagaag catatagagc agatgctgaa
    14281 ttagagtatg ggtacttaac accagcagtt ataaatgaca aagaatgttc aaagatagct
    14341 acagatgcag caattaagct atttggagaa gactgtataa cactatttga aaaagtaaca
    14401 ggagcagaag atttagctga gtttatgaat atagcacctg gtgcactagc atttgtagga
    14461 gctagaaatg agtcaaaagg tgcttgttat cctcatcatc atggatgctt taatatagat
    14521 gaagatgctc tagaaattgg aactgcttta tatgtgcaat atgcagtgga tttcttaaat
    14581 aaataatttt aatatactat aaagaaaaag cagagactaa gtttatatct ctgctttttt
    14641 attgtgtata ttttttataa atattgacta tataaaatat atatgatagc ataaagaaaa
    14701 tgataatcaa tatcaattaa aaagaaggtg atttatttga ataatgtaat atttgcattt
    14761 ttgataacat tattggctgg tttatctact ggtataggaa gttgtatagc attttttgct
    14821 aaaaaaacaa atactaagtt tctttctata agcttaggat tttctgctgg tgttatgatt
    14881 tatgtttcta tgatagaaat ttttcctaaa gcacaagatg ctttgacaaa atctatggga
    14941 gagaaattag gaagttggtc aactgtaata gcttttttta taggtatggc tatcattgct
    15001 gttattgata agctaattcc acaagaagaa aatccacatg aaataaagaa aatggagaat
    15061 atagaagaaa agaatatcaa aaaaaataag tctcttttga gaacaggtat atttacagca
    15121 atggctatag caattcacaa ttttcctgaa ggattagcta catttatatc agctcttgat
    15181 gatgttacaa tagctattcc gatagcaatt gcaattgcaa tacacaatat accagaaggt
    15241 atatctgtat ctgtaccagt ttattatgcc acaggagata aaaagaaagc tttttattat
    15301 tcctttttat ctggtatgtc tgagccttta ggagcgatta ttggatatgt acttcttaga
    15361 aattttttaa atgatataac tcttggaatt gtatttgcaa ttgtaggagg aattatggta
    15421 ttcatatcac tagatgaatt attgccatca gctagagagt acggggaaca tcatttatct
    15481 atttatggat tgattgcagg aatgggtgtt atggctatta gtttattact atttaaatag
    15541 ctttttaaat atatgattgt aacctaaaat tagtatcaaa atgatataat tatttaaata
    15601 gatttttaag ctatttaaaa atatcatttt ggagaatgag tgctatggaa aagaaaataa
    15661 aattcaaatt tgactggtat agttcacctg ataagataga gaaatggtta gaagatattg
    15721 aagctaaagg atataattta tataagataa ataaatttgg aggaatattt tattttcata
    15781 agggaagtcc aagaaaaata aaatacactg ttgattacta ctatgatgta gagaataatt
    15841 attttgatga acataaatca aatggctgga atcttgtatt taggagtatt ggtagtttta
    15901 tgggtacatc tgcatggtat atatggtcga aagaatacaa agacatacct cctaaattat
    15961 atagtgattc tgataaaaaa aacaaagtaa agtcaatttt atttatgaat atgtttatat
    16021 tctttatgtt agtagtaata tttatatatt tattgaatat tgaaataaga aatttatata
    16081 gtggttatgg agcatctgta actgctattg tactacagat tatattgttg attttatatg
    16141 cagtacaatt atataggaga ttaatgtatt atttaaggct taaaaagttt aaataaataa
    16201 aagaaggtgt cctaaaatta tttttttaat agtttaagac atcttctttt atcagtaagt
    16261 actgttttta attatagtaa tttctgtctt taaattgaaa tatcaaataa tagttatatg
    16321 ggattgagta ttgataaaaa taatttgaaa atgttatcct aaagtatcag a
//
LOCUS       DAGQVA010000090        16155 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.090, whole genome shotgun sequence.
ACCESSION   DAGQVA010000090 DAGQVA010000000
VERSION     DAGQVA010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.090"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..174
                     /gene="tuf"
                     /locus_tag="MIV85_003197"
     CDS             <1..174
                     /gene="tuf"
                     /locus_tag="MIV85_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005791980.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBY2962517.1"
                     /translation="VTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGG
                     RTVASGVVATIIE"
     gene            424..573
                     /gene="rpmG"
                     /locus_tag="MIV85_003198"
     CDS             424..573
                     /gene="rpmG"
                     /locus_tag="MIV85_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBY2962518.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            599..820
                     /gene="secE"
                     /locus_tag="MIV85_003199"
     CDS             599..820
                     /gene="secE"
                     /locus_tag="MIV85_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBY2962519.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            840..1382
                     /gene="nusG"
                     /locus_tag="MIV85_003200"
     CDS             840..1382
                     /gene="nusG"
                     /locus_tag="MIV85_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBY2962520.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1421..1846
                     /gene="rplK"
                     /locus_tag="MIV85_003201"
     CDS             1421..1846
                     /gene="rplK"
                     /locus_tag="MIV85_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBY2962521.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1917..2615
                     /gene="rplA"
                     /locus_tag="MIV85_003202"
     CDS             1917..2615
                     /gene="rplA"
                     /locus_tag="MIV85_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBY2962522.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2667..2795
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2838..3344
                     /locus_tag="MIV85_003203"
     CDS             2838..3344
                     /locus_tag="MIV85_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBY2962523.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3402..3767
                     /gene="rplL"
                     /locus_tag="MIV85_003204"
     CDS             3402..3767
                     /gene="rplL"
                     /locus_tag="MIV85_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBY2962524.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4159..4947
                     /locus_tag="MIV85_003205"
     CDS             4159..4947
                     /locus_tag="MIV85_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBY2962525.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5418..9134
                     /gene="rpoB"
                     /locus_tag="MIV85_003206"
     CDS             5418..9134
                     /gene="rpoB"
                     /locus_tag="MIV85_003206"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBY2962526.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9176..12661
                     /gene="rpoC"
                     /locus_tag="MIV85_003207"
     CDS             9176..12661
                     /gene="rpoC"
                     /locus_tag="MIV85_003207"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBY2962527.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12950..13372
                     /gene="rpsL"
                     /locus_tag="MIV85_003208"
     CDS             12950..13372
                     /gene="rpsL"
                     /locus_tag="MIV85_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBY2962528.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13496..13966
                     /gene="rpsG"
                     /locus_tag="MIV85_003209"
     CDS             13496..13966
                     /gene="rpsG"
                     /locus_tag="MIV85_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBY2962529.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14015..16081
                     /gene="fusA"
                     /locus_tag="MIV85_003210"
     CDS             14015..16081
                     /gene="fusA"
                     /locus_tag="MIV85_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBY2962530.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6326 a         2004 c         3296 g         4529 t
ORIGIN      
        1 gtaacaggag cttgtaagtt accagaagga atagagatgg taatgcctgg agataacgta
       61 acaatggaag tagacttaat aaactcaata gttgtagaag agggattaag attctcaata
      121 agagaaggtg gaagaacagt agcttcagga gttgttgcta caataataga gtaattcttt
      181 actaaactga tggattaaaa ggaataacaa aaagaggggt tatgctcctc tttttttaac
      241 atagaaatac aaaaacattg acacagcata ggattttgtg ataacttata caaggtaatg
      301 attataggaa gttaataata tcttgaatac tgtagatttt taataaatac atattttaaa
      361 gatattatat tcacatatat taacaatata tattattgta ttacaaagtt ggaggtgtat
      421 cagatgagag ttaaagtaac tttagcatgt acagagtgta agcaaagaaa ctacaacact
      481 actaagaata agaaaaataa tccagacaga atagaattac aaaaatattg tagattctgt
      541 aaaaagcata caactcataa agaaacaaaa tagtttttta taaggatgtg agtatggaat
      601 ggctgcccaa aaaaatgacg gtgcaaaaac taaaaaaagg tttagtttgt ttggatactt
      661 aaaagaaact aaacaagaat taaaaagagt tacatggccg acaaaaaagg aactgtttaa
      721 aaacacaagt atagttttaa ctgtagttat ttcatgcact atattagtat ggggtataga
      781 cactatatta tctggtgcac tagcgttatt actaaaatag acgaaaagag gtaagttaaa
      841 tgtcagaatt acaagaagca agttggtatg tagttcatac ctattcggga catgaaaata
      901 aagttaaagc tacaattgag aaagcagtta aaacaagagg tatggaagac tgcataagac
      961 aagtagttgt tccaacagaa gaagtagtgg aaactactaa aactggaaaa gaaaaaacta
     1021 gacaacgtaa agtttatcca agttatgttt tggttaaaat gataataact gatgaatctt
     1081 ggtatgtagt aagaaatact aagggagtta caggtttcgt tggacctggt tcaaaaccag
     1141 tgccattaag tgaagacgaa gtcaaagcta tggggataga cacaacagac cctaaagtag
     1201 taaatagcga tattgatttt gaaataggag atacagtaaa agtatctcaa ggaccattta
     1261 gtggacaaat aggtaacata gaagaaattg acttagaaaa tagagaagtc aaagtatgca
     1321 taaatgcatt tggtaaaagg actctatttg taatagagct tgaaggtata gaaaaaatct
     1381 aatactatat tatagaaaaa tctgaggagg tgcgctcaaa atggctaaaa aagttatagg
     1441 tcaaataaaa ttacaaatac ctgcaggaaa ggctactcca gcgccaccag ttggaccagc
     1501 attaggacaa catggtgtta atataatggg attcacaaaa gaatttaatg ctaaaactgc
     1561 agatcaagct ggaatgataa taccagttgt tataactgta tatcaagata gatcattcag
     1621 ttttataaca aaaactccac cagctgcagt tttaattaaa aaagcattaa acttaaaatc
     1681 aggttctgga gaaccaaaca agaaaaaagt tgctaaaatg acttcagctc aagtaagaga
     1741 aatagctgaa ttaaagatgc ctgacttaaa tgctgcatca gtagaagctg ctatgagtat
     1801 gatagctggt actgctagaa gcatgggtgt tgtaatcgaa gactaattaa aagatacact
     1861 tttttttata aagtgggagg ctagaagccg aaattaacca cgaggaggaa aataaaatgg
     1921 ctaaaaaagg taaaagatat gcaggtgcat tacaaaaagt agatagaact aaattttatg
     1981 atgcatcaga agcattaaca ttagtttcag atatagctgg agctaaattt gatgagacag
     2041 tagaagcaca cattaaatta ggtgttgact caagacatgc tgaccaacaa gtaagaggtg
     2101 cagttgtatt acctcatgga actggtaaaa caaaaagagt tttagttttt gctaaaggtg
     2161 aaaaagctaa agaagctgaa caagctggtg ctgactttgt aggagctgaa gaattagttc
     2221 aaaaaataca aggtgaaaac tggtttgact ttgatatagt agttgctact ccagatatga
     2281 tgggtgtagt aggtagatta ggtagagtat taggacctaa aggtttaatg ccaaacccta
     2341 aatcaggaac agttacattt gatgtagcta aagctataga tgaaataaaa gctggtaaag
     2401 ttgaatacag attagacaaa actaacataa tacatgttcc agtaggaaaa gtatcatttg
     2461 gtggagaaaa attaactgaa aactttactg cattaatgga tgctataata aaagctaaac
     2521 cagctgctgc taaaggacaa tatttaagaa gtataacagt agcttcttca atgggacctg
     2581 gagttaaaat aaacccagca agaacagctg aataataaaa ctgttgacac aggttgacaa
     2641 aaatgttatt atatcacttg tcaatgtaaa aaagaataga tttgccgtag atagtgggtg
     2701 cgaaagctta atatcccgcc gaggttttag ataaattgag attactaaag cttttgatgt
     2761 ctacttttgg caacaaaagc tttttataat gttgcggtaa atactaagcc tatttggtga
     2821 aggaggtgca catctatatg agaaaagcta tagaaattaa atcagaagtt gtttctgaga
     2881 tagttgaaaa gttacaaaaa tcttctgctg ctgttgttgt agattacaaa ggattaacag
     2941 ttgaagaagt aactgagtta agaaaacaaa tgagagaagc tggtgtagat tacaaagtat
     3001 acaaaaatac tttagttaga agagcagcta aagaagttgg tatagagcaa tttaatgatg
     3061 aattattagt tggaactaat gccatagcat ttggatatga tgatccagtt gctccagcta
     3121 gaatattaaa aggattcatg gattctcatc caaaaatgaa attaaagatg ggtattgtgg
     3181 aaggtgcatt ctatgatgaa tctaagattg ttgaaatggc taacatacca tcaagagaag
     3241 ttcttatcgc taaattactt ggtagcttaa aagctccagt atcaaacttc gcatacttaa
     3301 tagatgcaat agcgaaaaag gcagaaggtc aagaagaagc ttaattgctt aactaaaaaa
     3361 ttataaatat taatttgaaa taaaattcgg aggtgctaaa aatgacaata gaacaaatat
     3421 tagaagctat agaaaatatg aaagttttag aattaaatga attagttaaa gctgctgaag
     3481 aaaaattcgg tgtatcagct tcagctccag taatggtagc tggtgcagct gctggtggac
     3541 cagctgctga agaaaaaact gagtttgatg tagtattaac tgacgttggt tcttcaaaag
     3601 ttggagttat aaaagcagtt agagaaataa caggattagg attaaaagaa gctaaagaag
     3661 tagttgacaa tgctcctaag acagttaaag aaggagcttc taaagaagaa gctgatcaaa
     3721 taaaagagaa attagaagct gctggagcta aagtagaagt taagtagttt ctttaaaaag
     3781 atacccattg ggtatctttt tttatttata aaaaactata aagaaagtat ttggaattat
     3841 aaagaaagta tttttataaa ataaaaaaaa tttatataat agtactaaat taagggtatc
     3901 atatatgatg taatggtatt ttaatttaac attattatca aattaaaata taaacaattg
     3961 ttgtaatgtc tatatataaa gtatataatt aaactaaaat gtaaaatttt acattttagt
     4021 ttaaaaaaat acacgagtgt tttgtaaata aaatgtaata aataattaat taacaaatat
     4081 aaattttaaa ataagttaga tatttagaaa aatcgaaatt tgtaggattt aaaggacata
     4141 ttcaaggagg agttaataat ggaaaaatta caaggaaaaa ttgcagtagt tactgcagca
     4201 acaaaaggta ttggattagc atcagcagag atattagcaa aaaatggagc aactgtgtac
     4261 ttagcagctc gttcagaaga attagctaat gaagttataa ataaaataag tgcagaaggt
     4321 ggttgtgcta agtttgttta ctttaatgct cgtgaagaag agacctttac ctcaatgata
     4381 gaagaggtag ttaaaaaaga aggtaagata gatatacttg taaacaattt tggttcaaca
     4441 aacccttctc ttgacaaaga ccttgtaact ggggatacag ataatttctt tgacacagta
     4501 aatactaatt taaaaagtgt gtatttacca tgtaaagcag caattcctca tatgataaag
     4561 aatggaaaag gaagtatagt aaatatatca agtataggtt cagtattacc tgatttatct
     4621 agaatagctt actgtgtatc aaaagcagca atcaactcat taactcaaaa tatagctaca
     4681 caatatgcta aagacaatgt tagatgtaat gctgtacttc cagggcttat tgcaactaaa
     4741 gcagcattag acaatatgtc tccagagttc ataaaagaat ttttaaagca tgttccttta
     4801 aatcgtatag gggaaccaga tgatatagca aaagctgttc tattctatgc tagtgatgac
     4861 tcatcattta taacagggga tttacttgaa gttgcaggag gatttggttt acctactcca
     4921 caatttgcag ataatatatt aggataatta aattactaat atgcaatgaa agcttatgca
     4981 ttagttatag tagaaatgat atttttataa aggccataga tataatttat attggaaagg
     5041 tttgaggttc aaaattccaa gttaaattta tttatggtct ttattttgta tattttaata
     5101 aattgtatat atttgtataa atgtaattat ttacaatcat tttaatatgg aattataatt
     5161 aaataggggg gatggtactt gtataaaatt ttttatagaa aattagacct ataaatgaaa
     5221 aatatggatt ttatattgga aaattgtaca taatacataa tatatgctta aaataattta
     5281 caaaaaatca aaaataatgc atagtttaca tataagataa aaaatatatt gaaaaatact
     5341 tgacattatg ctaaaattat tagatgcgtt agaatgaact attgttttat ttttaattat
     5401 tgagaggtga aaagtgaatg ccacatcctg tcacgatagg taaaagaact agaatgagct
     5461 tttctaaaat taaggaaata gctgatgtgc caaatcttat agaaattcaa gtagattcct
     5521 atgagtggtt tttaaaagaa ggtttaaaag aagtgtttga tgatatttca ccaatagaag
     5581 attatactgg taatcttata ttggaatttg tcgactattc tctagatgat aaaccaaagt
     5641 acgatataga agagtgtaaa gagagagatg ctacatattg tgcacctcta aaggttaagg
     5701 taagacttat aaataaagaa acaggtgaga taaaagaaca agaagtgttt atgggtgact
     5761 tccctttaat gacagaaaga ggaactttcg ttataaatgg agcagaaaga gttatagtaa
     5821 gtcaattagt tagatctcct ggtgtttact atgcggaaga aagagataaa acaggtaaga
     5881 gattgatttc atctactgta attcctaata gaggagcatg gttagaatat gaaacagatt
     5941 ctaatgatgt aatatctgta agagttgata gaacaagaaa acaaccagtt acagttttac
     6001 ttagagcttt aggaatagga acagatgcag agataattga ccttttagga gaagatgaga
     6061 gattatctgc tacattagaa aaagataata ctaagacagt agaagaaggt cttgtagaga
     6121 tatacaaaaa attaagacca ggtgaacctc ctactgtaga aagtgcatca tctttattaa
     6181 atgctttatt ctttgaccca aaaagatatg acctagcaaa agttggtaga tataaattca
     6241 ataagaaact tgctttatgt tatagaataa tgaataaaat ttcagcagaa gacataataa
     6301 atccagaaac tggagaagta tttgtaaaag ctggagaaaa aataagctat gatttggcta
     6361 aagccataca aaatgcaggt ataaatgtag taaatctact aatggatgat gataaaaaag
     6421 ttagagttat aggaaataat tttgtggata ttaagtctca cattgatttt gacatagatg
     6481 atttaaacat aaaagaaaaa gtacattatc caactttaaa agaaatttta gatggatata
     6541 gtgatgaaga agaaataaaa gaggctataa aatcaagaat taaagaactt ataccaaaac
     6601 atatattatt agatgatata atagcttcaa taagttatga gttcaatata ttctataata
     6661 taggaaatat tgatgatata gatcacctag gaaacagaag aataagatct gtaggtgaat
     6721 tgttacaaaa tcaagttaga attggtcttt caagaatgga aagagttata aaagaaagaa
     6781 tgacggttca agatatggaa gctataacgc ctcaagcgtt agttaacata agaccagttt
     6841 cagctgcaat aaaagaattt tttggtagtt ctcagttatc tcagttcatg gatcaaacaa
     6901 atcctctatc tgagttaacg cataagagaa gattatcagc ccttgggcct ggaggtcttt
     6961 caagagaaag agctggattc gaagtgcgtg acgttcacca ttcacactat ggtagaatgt
     7021 gtccaataga gactccagag ggaccaaata tcggtcttat aaactctcta ggaacttatg
     7081 caaaaataaa tgaatttgga tttatagaat caccatatag aaaatttgat aaagaaacat
     7141 caacagttac tgatgaaata cattatttaa ctgctgacga agaagattta ttcgtaagag
     7201 ctcaggcaaa tgagccatta acagaagatg gtaaattcgt aaaccataga gttgtttgta
     7261 gaactgtaaa tggtgctgtt gaaatggttc ctgaaagtag agtagattac atggatatat
     7321 ctcctaagca ggttgtatct gttgccactg ctatgatacc tttcttagaa aatgatgatg
     7381 ccaaccgtgc ccttatggga gcgaacatgc agcgtcaggc agtgcctcta gttagaagag
     7441 aagcaccaat tataggaact ggtatagaat acagagcagc aaaagactct ggagcagttg
     7501 ttgttgctag aaattctggt atagcagaaa gagtaacagc agatgaaata attataaaaa
     7561 gagaagatgg aaacagagat agatataatc tacttaagtt taaacgttca aactcaggta
     7621 cttgtataaa tcaaacacct ataataaata agggtgacca gataataaaa ggtgatgtta
     7681 tagcagatgg tccagcaact gatttaggag aagttgcact tggaagaaac tgtcttatag
     7741 cattcatgac ttgggaaggt tataactacg aggatgctat attaataaat gaaagattag
     7801 ttaaagaaga tagattatca acaattcata tagaagaata tgaatgtgaa gctagagata
     7861 caaaactagg gccagaggaa ataactagag atatacctaa tgttggagat agtgcaatta
     7921 agaacttaga tgacagaggt ataataagaa taggtgcaga agtagactca ggtgatatat
     7981 tagttggtaa agtaactcca aaaggagaaa ctgaacttac tgctgaggaa agattacttc
     8041 gtgcaatatt tggagaaaag gctagagaag ttagagatac ttcacttaaa gtgcctcatg
     8101 gtgaatctgg tataatagtt gatgtaaaag tatttactag agaaaatgga gatgatttat
     8161 ctccaggagt aaatgaatta gtaagatgct atatagctaa aaagagaaaa ataaaagttg
     8221 gagataaaat ggctggtcgt catggtaata aaggggttat ctcaagagta ttacctgaag
     8281 aagatatgcc attcatggaa aatggaacac cactagacat aatacttaac ccacaaggta
     8341 taccatcacg tatgaacatt ggtcaggttt tagaagttca tttaggactt gctgctaaga
     8401 cattaggatg gtatgtagca acatcagtat tcgatggtgc taatgagtat gacataatgg
     8461 atgctcttga agaagctggg tatcctagag atggtaaatt aactttatat gatggtagaa
     8521 caggtgagtc ttttgacaac agaataactg ttggatatat gtactacttg aaactacatc
     8581 acttagtaga tgaaaaacta catgcaagaa gtactggacc atactcatta gttactcaac
     8641 agccactagg tggtaaagca caatttggtg gacaaagatt tggagagatg gaggtttggg
     8701 ctctggaagc atatggagct gctcacatac ttcaagaaat acttactgtt aagtctgatg
     8761 acgttgtagg tcgtgttaga acatatgaag ctatagttaa aggtgaaaat atacctgaac
     8821 caggaatccc agaatcattt aaggttctta taaaagaact tcaaagttta tgcttagatg
     8881 taaaagtatt gacagatgaa gaccaagaaa tagaagtaag agaatctgtg gatgaagatg
     8941 atacaatagg tgaatttgag ctagatgttg taaatcatat gggagaagtt gaagaaagta
     9001 atataataga agaaattgaa gatgattttg cagaaaatgc agaagatgag gatatagaga
     9061 atttagaaga attcactgaa gatgatttat ttgaagaaga aatagatttt gatagtgatg
     9121 actttgatat gtaaatttaa ttaatgtaaa tctcaaatag aagggagaga actccttgtt
     9181 tgaattaaac aatttcgagt cgataaaaat agcattggct tctccagaaa aaataagaca
     9241 atggtctagg ggagaagtta aaaagccaga aactataaat taccgtactt taaaaccaga
     9301 aaaagatggt cttttctgtg aaagaatatt tggaccacaa aaagactggg agtgccactg
     9361 tggtaaatat agaagagtta gatataaagg tgtagtttgt gatagatgtg gagtagaagt
     9421 aactaaatca aaagtaagaa gagagagaat gggacatata gagctagctg ctcctatgtc
     9481 tcacatctgg tacttcaaag gtataccaag tagaatggga cttttacttg atatgtcacc
     9541 aagatcgtta gaaaaaatat tatactttgc ctcatatgtg gtagttgatc caggagagac
     9601 tggattaaac gaaaaacaat tgcttacaga aaaagaatac agaactgctc ttgaaaagta
     9661 tggatatact tttactgtag gaatgggtgc tgaagctgta aagacattac tacaaaatat
     9721 agatttagag caacaaagta aagacctaag agcggagtta aaagatagta cagggcaaaa
     9781 gaaagttaga acaataagaa gattagaagt tgtagaggca tttaaaaagt ctggaaataa
     9841 accagaatgg atgattttag atgcaatacc agtaatacca ccagatttaa gaccaatggt
     9901 acaacttgat ggtggaagat ttgcgacttc agacctaaat gatttatata gaagagttat
     9961 aaatagaaac aatagactta aaagattatt agagcttgga gctccagata taattgtaag
    10021 aaatgaaaaa agaatgcttc aagaagctgt tgatgcattg atagataatg gtagaagagg
    10081 tagacctgta acaggacctg gaaatagacc acttaaatct ttatcagata tgttaaaagg
    10141 taagcaaggt cgtttccgtc aaaacttact tggtaagcgt gttgactact caggacgttc
    10201 tgttatagtt gttggaccag aacttaaatt ttatcaatgt ggacttccaa agaagatggc
    10261 attagaatta ttcaagccat ttgttatgga taaattagtt aaagaaggtt atgcacataa
    10321 tataaaaagt gcgaaatcta tagtagaaaa agttaagcca gaagtttggg atgttttaga
    10381 agatgttata aaaagtcatc cagttcttct taaccgtgca ccgactctac atagattagg
    10441 tatacaagca tttgaaccaa tcttagttga aggtaaggct ataaaactac atcctcttgt
    10501 atgtacagct tataatgcag actttgatgg tgaccaaatg gcagtccatg tacctttatc
    10561 agtagaagca caagcagaag caagattctt aatgctttct gtaaataata tacttgctcc
    10621 taaagatggt tcacctataa ctactccatc tcaggatatg gttttaggtt gctattatct
    10681 aacaatagaa gcccaagatg gagctaaagg aacaggtatg gtatttaaag actttaatga
    10741 actattactt gcttattaca ataaatcagt tcatctacat gcattagtga aactgaaggt
    10801 aacacttgaa gatggaagaa gttcattggt tgaaagtact gttggtagat ttatatttaa
    10861 tgaaaatata cctcaagact taggttttgt agatagaaaa gaaaatccat ttgcacttga
    10921 agttgatttc ttagcagata aaaaatctct tggtaaaata atagataaat gctttagaaa
    10981 acacggaaat acagaaacag ctgaattact agattatata aaagctctag gatttaaata
    11041 ttctacatta ggtggtataa cagttgctgt tgatgatatg agtgtcccag aagaaaagaa
    11101 agtatttata gctgaggcag aagctaaagt tgataagtat gaaaaagcat acagaagagg
    11161 tctaatctct gatgaagaaa gatatgaaaa agttatagag acatggacag aaacaactga
    11221 taaagttact gatgctctta tgggtggact agatagatta aataatatat atataatggc
    11281 acattcagga gccagaggtt ctaaaaacca aattagacag ctggcaggta tgcgtggtct
    11341 tatggcaaat gcatctggta aaacagttga gataccagtt aaatctaatt tccgtgaagg
    11401 tttatcagta ctagaatact ttacatcttc acatggtgcc agaaaaggtc ttgccgatac
    11461 agctatacgt acagctgaat ctggatattt aacaagaaga cttgttgatg taagtcaaga
    11521 tgttattgta agggaaatag attgtggaac agaagatact acagagattt atgctataaa
    11581 agaaggaaat gaagttatag aagagatata tgatagaatt gtaggaagat atactataga
    11641 ccctatatta aatcctgaaa ctggagaagt tatagttgag gctgattcaa tgatacaaga
    11701 agatgaagca gaaactatag tagctttagg aattgaaaaa attaggataa gaacagttct
    11761 taactgtaaa actaatcatg gagtttgttc taagtgttat ggtagaaact tggcaacagg
    11821 aaaagaagtt aatataggtg aagcagttgg tataatagca gctcaatcta tcggtgagcc
    11881 gggtactcag cttacaatgc gtacattcca tactggagga gttgcaggag ctgatataac
    11941 tcaaggtcta ccaagggttg aagaattatt tgaagctaga aaaccaaaag gattagctgt
    12001 aataactgaa gtatctggta gagttgaaat tgatgaaaca ggaaagagaa aagaagtaaa
    12061 tgtaatacca gaagaaggcg agactcaaac atatgtaatt ccatatggtt ctagattaaa
    12121 agttaagcaa ggtcaaatgc tagaggctgg agaccctcta acacaaggat ttataaatcc
    12181 tcatgatata gtaagagtaa atggtgttaa gggagttcaa gaatatatag ttaaagaagt
    12241 tcaaagagtg tatagacttc aaggggttga tgttaatgat aagcatatag aagttatagt
    12301 aagacaaatg ctatctaaag taaaagttga agacccagga gatacagatt tattgccagg
    12361 tggatatgaa gatgtattaa cattcaatga atgtaataaa gatgctatag ataaaggtct
    12421 aagaccagca gttgctaaaa gagttttact tggtataact aaagcatctc ttgcaactga
    12481 ttcattctta tcagcagctt ctttccaaga aacaacaaga gtattaacag aggcagcaat
    12541 aaaaggtaaa gaagaccact taataggact taaagaaaat gttatattag gtaagttaat
    12601 accagcagga acaggaatga agaaatatag aaatatagct gttgaaaaaa ttgaagatta
    12661 atagcatata gagtaaagaa atcttgacaa ccattatttg tggtgttaaa atagtaaagt
    12721 gtgttgttta aaagtacact aagggcttga acaagttctt agtgactttt agatggcaat
    12781 aaatgagaac taaaaagcat caagctagaa aagtgctaat atcacatatt tatgtgttat
    12841 agacattaaa ttgtaagtaa cgaatgttac aatcagtcag tatgaatatt catattgatg
    12901 tagttggcgg tcactgataa gatcgaaaat ttggaaggag gtgcagatga tgccaacaat
    12961 taaccaatta gttcgtaaaa gtagaaaagc gctagagaag aaatctactg ctccagcatt
    13021 acaaaaaggt tacaactctt taaataagaa agtaactgac gctagtgccc cacaaaaaag
    13081 aggggtttgt acttcagtaa aaacagttac tcctaagaag cctaactcag ctttaagaaa
    13141 agttgccaga gttagattaa ctaatggtat agaagtttct gcttatatac caggagaagg
    13201 acacaactta caagagcata gtgttgttct tataagagga ggaagagtaa aagaccttcc
    13261 aggggttaga taccatatac taagaggtac tctagataca gcaggtgttg ataagagaag
    13321 acaatcaaga tctaaatacg gtgcgaagag acctaaagaa gctaaaaagt aaaaacaatt
    13381 aatgattgat tatagttcgg tgctttaaat atatatatat ttacggcatc acggcattaa
    13441 atgatttatg tcgagtacct atgatttaag ttaaataatt aaggagggaa gcgaaatgcc
    13501 aagaaaaggt aatattccaa aaagagaagt tttaccagat cctatgtatg ggagtaaggt
    13561 agttactaaa ttaataaata atctaatggt agacggaaaa aaaggaaagt ctcaaagaat
    13621 agtttatgat gctttcgcaa ttgttgctga aaagacagga gaagaagctt tagaagtatt
    13681 taataaagca atggataata taatgcctgt tttagaagta aaagcaagaa gagttggtgg
    13741 ggcaaactac caagtgccaa tcgaagttag acctgaaaga agacaaacat taggtttaag
    13801 atggctagta aaatatacta gagctcgtgg agaaaaagga atggttgaaa agctagctaa
    13861 agagataatg gacgcagcta acaacactgg agcttcagtt aagaaaaaag aagatactca
    13921 taaaatggca gaagctaata aagcatttgc tcattacaga tggtaggata tatagatatc
    13981 ttataaaatt gaggatatca taaggaggat aaccatggct agaaagtttc ctttggaaag
    14041 aactaggaat ataggaatca tggctcatat agatgcagga aaaactacta ctacagaaag
    14101 aatcctgttt tatactgggc aaactcataa aataggagaa actcatgaag gagcttctca
    14161 aatggactgg atggagcaag aaaaggaaag aggtataaca ataacttctg ccgctactac
    14221 tgcttcatgg aaagaccata gaataaacat aatagatact cctggacacg tggacttcac
    14281 agttgaggtt gaaagatctc taagagttct tgacggttca gttgctgtat tctgtgcaaa
    14341 aggtggggtt gagcctcaat cagaaaatgt atggagacaa gctgaaactt atggagtacc
    14401 tagaatagct tttgtaaata aaatggatat attaggtgca gatttctaca atgttgtaag
    14461 catgatgaaa tctagattaa attctaatgc agttcctatg caattaccaa taggtaaaga
    14521 agattcattt ataggtataa tagacttatt aaaaatggat gctgttatat acaaagacga
    14581 cctaggggtt gaaatggaag aaacagatat accagaagat atgaaagaat tagctgctga
    14641 gtggagagaa aaattagttg aatcagtagc tgaaactgat gaagaattaa tgatgaaata
    14701 ccttgaaggt gaagaactta ctatagatga attaaaagtt gctataagaa aagctactat
    14761 agcttgtgaa atgaacccag ttttctgtgg tacagcttat agaaacaaag gtgttcagtt
    14821 agtaatagat gcagttttag attacttacc agcgccaact gatataccag ctataaaagg
    14881 tatattagca gatggagaag aagctgaaag acattcttct gatgaagagc cattctctgc
    14941 attagcattc aaaataatga ctgacccatt cgttggaaaa ctagcgttct tcagagttta
    15001 ttctggaaca ttagaatcag gttcttatgt tttaaatgca actaagaata agagagaaag
    15061 aattggtcgt atattacaaa tgcatgctaa tacaagagaa gaaataacta aagtgtatgc
    15121 tggagatata gcagcagcag taggattaaa agatactact actggagaca cattatgtga
    15181 ccctgctaat ccaataatac ttgaatctat ggaattccct gagccagtta tatctgttgc
    15241 tatagaacca agttctaaag cagctcaaga aaaaatgggt atagctcttc aaaaattagc
    15301 tgaagaagac ccaactttca cagttaagac tgaccaagaa acaggacaaa ctataatatc
    15361 tggtatgggt gaattacact tagagataat agtagataga ttattaagag aatttaaagt
    15421 agaagctaaa gttggtgcac cacaagttgc atatagagag actataactc aaccagttga
    15481 tgttgaatac aagtactcta agcaatcagg tggtagagga caatacggtc acgttaagat
    15541 tagagttgct cctcaagagc caggtgaagg atacaaattc acaaacaaaa ctgttggtgg
    15601 atcagtacca aaagaatatg ttggtccagt tgacatgggt atacaaggag ctatgcaatc
    15661 tggtatagtt gctggatatc cagttgtaga cgttgctgtt gagttatatg atggttctta
    15721 ccatgaggtt gactcttctg agatggcgtt taagatggct ggttcaatgg cattcaaaga
    15781 tgctatgaag aaaggtaatg cagttctttt agagccttac ttcaaagtag aagttgttac
    15841 tccagaagat tacatgggag atgttatggg tgacttaaac tcaagaagag gattaatcca
    15901 aggtatggaa gctagaagtg gtgcacaagt tataaatgca ttcgttccac tttcagaaat
    15961 gtttggatac tcaacagacc taagatcttc aactcaaggt cgtgcaactt acacaatgat
    16021 attcgatcac tatgagcaag ttccagcttc agttgctaag aaaatagctg aaggaaaata
    16081 atttaaaaat aattaataat ataaatataa aaaataatca gctagatgag agatatctct
    16141 catctagcac aagat
//
LOCUS       DAGQVA010000091        15901 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.091, whole genome shotgun sequence.
ACCESSION   DAGQVA010000091 DAGQVA010000000
VERSION     DAGQVA010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15901
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.091"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(207..1304)
                     /gene="ychF"
                     /locus_tag="MIV85_003211"
     CDS             complement(207..1304)
                     /gene="ychF"
                     /locus_tag="MIV85_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBY2962531.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            1620..2885
                     /locus_tag="MIV85_003212"
     CDS             1620..2885
                     /locus_tag="MIV85_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBY2962532.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRKLYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            2900..4186
                     /locus_tag="MIV85_003213"
     CDS             2900..4186
                     /locus_tag="MIV85_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBY2962533.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            4580..5326
                     /locus_tag="MIV85_003214"
     CDS             4580..5326
                     /locus_tag="MIV85_003214"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBY2962534.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            5356..6291
                     /gene="rsmH"
                     /locus_tag="MIV85_003215"
     CDS             5356..6291
                     /gene="rsmH"
                     /locus_tag="MIV85_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBY2962535.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            6772..7119
                     /locus_tag="MIV85_003216"
     CDS             6772..7119
                     /locus_tag="MIV85_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962536.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            7131..9110
                     /locus_tag="MIV85_003217"
     CDS             7131..9110
                     /locus_tag="MIV85_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBY2962537.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILGE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIEAFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            9277..10650
                     /locus_tag="MIV85_003218"
     CDS             9277..10650
                     /locus_tag="MIV85_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBY2962538.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            10691..11659
                     /locus_tag="MIV85_003219"
     CDS             10691..11659
                     /locus_tag="MIV85_003219"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBY2962539.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            11678..13033
                     /locus_tag="MIV85_003220"
     CDS             11678..13033
                     /locus_tag="MIV85_003220"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBY2962540.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASVIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            13085..14215
                     /gene="spoVE"
                     /locus_tag="MIV85_003221"
     CDS             13085..14215
                     /gene="spoVE"
                     /locus_tag="MIV85_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBY2962541.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            14233..15459
                     /gene="murG"
                     /locus_tag="MIV85_003222"
     CDS             14233..15459
                     /gene="murG"
                     /locus_tag="MIV85_003222"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBY2962542.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            15729..>15901
                     /locus_tag="MIV85_003223"
     CDS             15729..>15901
                     /locus_tag="MIV85_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HBY2962543.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKEL"
BASE COUNT         6262 a         1692 c         2898 g         5049 t
ORIGIN      
        1 ataatttata aatttaaatg ttatatatgt aagtaatttt attatatcaa aaaaagagtt
       61 tttcataata atttatacaa atcatttgaa atactcttct tttattttta aattctatat
      121 aattattata agataatatt gtattattat aatcttagtt ttttagttat tatatataat
      181 agtcaaagtg tatacgatta atcattttaa acattaaatc taaataatat tacatctcca
      241 tctttaacta tgtattcttt accttctaat ttaaccaacc ctttttcttt agcagcagcc
      301 atagtaccat gctcaaccaa atcattaaag gctattgttt ctgctctgat aaatcctctt
      361 tctatatcag aatgtatttt tcctcctgcc tgaggagctt tacttccaac ttttatagtc
      421 catgctctaa cttcttttgg accagcagtt aagaatgaaa ttaaaccaag taaagcataa
      481 gaagatttta taagcttatc aagccctgat tgttcaagac ctaatgtttc taaaaactct
      541 ttcttttctt cagcagaatc aagttcagaa atttctgctt ctatttgtgc acatactaca
      601 acaacttcgg catcttctgt ttctgcaaat gctttaactt gttgaacata tttattattt
      661 tctccattat cagctaaatc atcttctgat acatttgaag catatattac aggcttagat
      721 gtaagtaaat ccaatgaatt tacaaatgtt tgttcatctt ctgtaaattc catagttctt
      781 acacacttac tttcttctaa agtagacatt attgatttta ataaatcaag ttcagaacct
      841 aaagttttat cagccttagc agctttttga gttttattaa ttcttctttc aagaatctct
      901 atatctgaga aaattaattc taagtttata gtttctatat cacgaagtgg gtctacagaa
      961 ccatctacat gtacaacatt ttcatcctca aaacatctaa caacatgaac tattgcatca
     1021 acttctctta tatgtgataa gaatttattt cctaaacctt ctcctttaga agctcctcta
     1081 actaaacctg ctatatcaca aaattctata gcagtaggaa ctattttttc agaattatat
     1141 aattcttgta gtttgtttaa tctttcatct ggaacagata caactcccac atttgggtct
     1201 attgtacaaa aagggtaatt tgcagattct gcacctgctt gagttattgc gttaaatagt
     1261 gtgcttttac ctacatttgg taaaccaact atacctaatt tcatattaat cgtcctctct
     1321 cttattcttt tttatattct ttatataact ttaaacaatc aatctatagg attgcaaaat
     1381 tgttttaatt atagacatac atattgatta tacatcatat atatcaagct tgtaaactag
     1441 actttaaagc atattgattt aaataatatt tgtatttaat ttaaataaaa atattgcttt
     1501 tagaaaataa taaaaaggat ataattaaat agaaggtttt tatatgtgag tatatgtaat
     1561 taaaaaataa ataaatttca attttaaaat tgatgtttaa ataaaaatag gaggtacata
     1621 tggttaatac taaaaaaata ataaatttag gtaataatat taatcttact ttgataaaaa
     1681 cagaaaagtt taaatcgaat cttataagtt tatatgttca gagactattg gatgaaaaag
     1741 aaactacaaa aaatgctcta ataccatcaa taatagcaag tggaagcgct aaatatccta
     1801 gtgctagagc aatatccaat aaattagatg atttatatgg ttcatctatg ggagctgatg
     1861 ctgtaaaacg tggagaacgt caagtattga gttttaaagt aattaacata agtgaaaagt
     1921 atttagatga gagtatattt gaagaagtag tagaattttt taatgaagta ataaataata
     1981 cgcttgttgt agatggtggg tttaaagaag aatatttaaa tattgaaaaa gagaatttaa
     2041 gagaaaagat acaatcaata ataaatgata aaaaggaata tgcgcaagat aaatgtattg
     2101 aggctatgtg taaaggagag agatatagtg taagtgaatt tggttatgaa gatgaaatag
     2161 atagtataac ttcaagaaag ttatatgaac attataaaaa catacttaaa acatcaccta
     2221 tagatatagt tgtagaaggt aattttgatg aagataaagt tgtagatata ataagtaaaa
     2281 atctaaaatt tgaaagagaa gaaattataa atataccaag agcagatttt ataaaaaatg
     2341 tggatgaggt aaaagttata gatgaacaaa tggaaataac tcaaggtaag ttagttatgg
     2401 gttatagagc aaatgtggat tatgcagaca tagataaata ttatgcttta gtagttggga
     2461 gcaatgtctt aggtggtggt ccacactcta aattatttgt taatgtaaga gaaaaagaaa
     2521 gtttatgtta ctatatattc tcttcaatag agaagtataa aagtatcatg tttatatcat
     2581 ctggtataga aactaaagat tatgataaag ctgtagaatt gataaaaaaa caagtagaaa
     2641 gtgtaaaagc aggtgatata tctgatgaag aattagaaaa cagtaaactt gctttagtta
     2701 attctatgaa atctataact gataatatag gtggtatgtc tgattttgtt ttctctcaat
     2761 ctatggcaaa gacaaattct gaagtacaag atataatatc tagtatagaa aaggttacaa
     2821 aaaaagatat agttgaagct ataaaaaata tagagcttga tactgtatac ttcttgagaa
     2881 attaatggag gagatgtcta tggaaaaaat agttaatgat atattgaaag aagaagttta
     2941 ttatgagaaa ttgcaaaatg gattagatgt atattttatg cctaaaaggg gttttatgaa
     3001 aaagtatgct attttggcta ctaattatgg ttcaaatgac ttagaatttg taccaattgg
     3061 agaagataag aaaattagag tgaatgaagg tattgcacat tttctagagc ataagatgtt
     3121 tgagcaacct gatggaggag atgcatttga taaattttca aaattaggag taaatgcaaa
     3181 tgcatttact aattttacaa tgacagccta cttattttct gctactgaaa atttttatga
     3241 gagtttagaa catctaattg actatgttca aacaccttat tttacagatg aaaatgttga
     3301 aaaggaaaaa ggtataatag cacaagagat aaaaatgtac aatgatgacc ctgattggaa
     3361 tgtatacttt aattgcttga aggcaatgta tgtaaattat cctgctagaa ttgatatagc
     3421 aggtactgtt gatagtatat ataagataac taaggaagag ctatataaat gttataatac
     3481 tttctataat ccaggaaata tggctttatt tgttgttggt gacttagatg tagaaaaagt
     3541 tatagatgta actaaaaagt caaacaatta caaagtagac aaactctcta agagtataga
     3601 aagattttat ccagaagaac cagaaggtgt aaaagaaaaa gaggttatag aaaaattccc
     3661 tatatctatg cctatgttca acataggttt taaagatagt aatgttggtt taaaagggaa
     3721 agaactttta cgtaaagaga ttgtaactga tatacttgta gggatgttat ttaaaaaagg
     3781 aagtaagctt tatgaagatt tgtatatgca aggtttaata aatgaaaatt ttggagctgg
     3841 attttcgtct caagtggatt atgcttttag cataatagct ggagattcta aagagcctaa
     3901 aaaagtaaaa gaaataattc ttgattatat agaaaaatca aaaaaagaag gattatcaaa
     3961 agaagagttt gagagaacta aaaagaaaaa aatagggtca tttattaagt gctttgattc
     4021 tataaacttt ataggtaata gttttatatc ttatgttttt aaggatataa atctattgga
     4081 ttatttagat attattaaag atattacttt tgaggaagtt gaagaaagat taaaagagca
     4141 ttttaaagaa gagtattgtg ttatttctat tgtagagcct aaatagaaac ttaatcataa
     4201 taagaataac taattaagta ttagtttatg tttttaaatg tttattttgg taaaacaaat
     4261 ttataaaata tatttatata aattgaggta aaaatttaag agctatagat aagaaataga
     4321 agaggttgat gtatatatgc atcaatcttt ttgattaaaa aatatctatg tacacttgta
     4381 actttagtca tgagagattc agtttaaaaa attttatagt aattagatat aatatagtgt
     4441 agggagttgt agaataaatt ttaatatttt ttgtagaatt aacattaatg tgttatcata
     4501 atttagtata attacaatta attgtaatta tagcatattg ctttggaaat attttcaatt
     4561 aatacaaaga ggtgacgtta tggatagagt agcatttaca ctgtttggca tagacatcat
     4621 gtggtatgga atacttatgg catgtggaat gattttagga actttaatag caataaaaga
     4681 agcaaaaaga gtgggaatta aagaagatga tgtattaaat atagctataa tagcaattcc
     4741 agttggacta atctgtgcaa gaatctatta tgttgtattt aattggagtt actatgctca
     4801 aaatatgtct caaattttta attttagagg tggtggcctt gctatacatg gagggttaat
     4861 tggtggaata ttagctggtt atatatacac taagattaaa aatattaact tcttaaaaat
     4921 ggctgataca gttatacttg gaatgccttt agcacaagct attggaagat ggggaaattt
     4981 tattaatgga gaagcacatg gaggtgctac caatttacct tggggaataa tggttgatgg
     5041 agtaaaggta catccaactt ttttatatga gtctatatgg gattttggaa tatttatagt
     5101 tttattacta tttagaaaaa ataaaaaata tgaaggtcaa gttatagtta cttatataac
     5161 tttatattca ataggaagat tttttataga gggattaaga acagatagtt taatgttagg
     5221 accacttaga atggcacaag ttataagtct aattggagtt attggtggca taattgcaca
     5281 tgtttattta tcaaagaaaa ataaaaataa tattagtgaa gaatagttta aaaagtgaat
     5341 ttaagggagg taactatgga atttcatcat gtatcagttc ttttaaatga gtgtatagag
     5401 aatttaaata taaagccaga tggcgtgtat gttgactgta ctatgggagg agcaggacat
     5461 tctaaagaaa tagtaaaaaa actgtcagat aagggattat ttatagggtt tgaccaagat
     5521 aaaaatgcta taagcacagc aaaagagaga ttgagtgaat atgaaagtag agtgaagttt
     5581 gttcacagca attttgaaaa tataaaagag gaattagaaa aaataggagt ttacaaaatt
     5641 gatggtgtat tagctgattt aggagtttca tctcatcaac ttgatgaagc tgatagagga
     5701 ttttcttata tgcaagatgc accacttgat atgagaatgg atgttaggtg tgagttttct
     5761 gcatatgatg ttgtaaatac ttatacagaa gatgaattaa ctaagataat aaaagattat
     5821 ggagaagata actgggctaa gcgtatagct aaatttatag ttgaagaaag agcaaacaaa
     5881 ccaatagaaa ctacaggaga attagtagat gtaattaaaa aagctatccc taagaaagct
     5941 agaatagatg gacctcaccc agctaaaaga acttttcagg caatacgaat agaagtaaat
     6001 aatgaacttg gagtaattac aaagatgata aatgatgctt cttctataat gaatgaaggt
     6061 ggaagaatat gtataataac attccattca ttagaagata gaatagtgaa aaatgcattt
     6121 aagcatttag catcagattg tatatgtcca cagcatttac ctatatgcca atgtgataaa
     6181 gaatctgagg tgaaaataat aactagaaaa cctatattac ctagtgagga agaaatagaa
     6241 gtaaatccac gttcaagaag tgctaagcta agagtagcag aaaaaatata agtagttata
     6301 aggctaaaga ataatcttat atataagatt attataatta attaaaaagt attatatatt
     6361 ttgttgcact ggtaaagcaa ttaaaaaaca attaacacta taagaaatgt tctttgttat
     6421 tgagatataa aatgaaaatt tagatataaa aatatagata tagatggtat taagtaatat
     6481 aatggagaac ttaggaatca gagagtagat agttagttac atattatatt tatggaagaa
     6541 attatctaaa aatactagaa gtgataaaaa taaatagaaa ttaatatcta acctatagat
     6601 tcatataaaa gtataagtga atttataggt ttttgttgtg tatagaaaaa aatacaatta
     6661 gattgtgtaa tagtgtatta atttagcgat gaaattttag aggaagaaat atgattaata
     6721 acaaatatag tatagaggaa aatttaaact atatactatc ggggtgagaa tttgaaaaaa
     6781 aattataaaa tacataatct aaatgaatat aaaaataaaa aaaagaataa ttataaaaag
     6841 agaaataaga aaaaaatagg agctaaatgc attttactga ttgcaacttt ttcagtaata
     6901 atattgaatc tatgtggtta ttcaaaaatc tcggaaatga agtacgatat ctattattta
     6961 caaaaagatt taagaaaaaa agagatagta ttagaggaac taaaggcaaa agaaactgaa
     7021 aaaacatcaa taaaagaaat tgagctaaag gctaaggaat tgctcaatat ggactatcca
     7081 aaagatggac aaataaagta tatagatgtg gataactagg gggaatagat ttgagaaaag
     7141 taaagaggat aagtaagaaa aggctggtac tcgttcttat tctagcatgt gcattgtttt
     7201 tttgccttgt tattaggact gggtatctac aacttatgaa gggaaattgg ttgagtacaa
     7261 aagcactaga acaacaaaca agagatatac caatagaacc caaaagagga actatatatg
     7321 atagaaatat gaaagagtta gcagtaagtg taactaagta tactgtttgg tgtaaacctg
     7381 tggaagtaga agataaaaaa gaagcagccg aaaaggtagc tgagattttg ggtgaagatt
     7441 ataaagatat ttacgcttta ataagcaaaa aaaatatggc tcttgtaaaa gtaaaaagat
     7501 ggatagatga tgataaggca agtcaaataa gagatgctaa attaagtgga atatgggtag
     7561 cagaagataa tcaaagatat tacccatatg ggaattttgc accatatgtg ttaggacata
     7621 cttcttcaga tgcaacaggt atatctggtg tagaaatgca atatgataaa aagttaaaag
     7681 gaaagcctgg aaaacttata gtaagtactg atgcttcagg aagagaaata ccacaaggaa
     7741 tggaaaaata ttatgagcct gtacaaggta atggtcttgt gttgtctata gatgaagtaa
     7801 ttcaacacta tactgaaaaa gcagtacaga aagcttatga gttaaataat gcaaaaaaag
     7861 ttactgcaat agctatgaac cctaaaacag gtgatatact tgctttagca tcaaaaccag
     7921 attatgaccc taatgattca agaacgccaa tatatccata ttatcaagaa gaacttgaaa
     7981 aatataatga taaagataaa ataaaaggct attatcaaat gtggagaaat ccagcagtaa
     8041 gtgatacata tgaaccaggt tctacattta agcttattac atcttccagt gctcttgaag
     8101 aaggagtaat taaagatgga gaaaaattca catgtacagg tagtgtaact gttggaggaa
     8161 gaaagattaa atgttggaga cattacagac ctcatggaac acaagaattt aaacaagcag
     8221 tacaaaactc ttgcaaccca gtatttgttg agttaggaag cagattaggt gttggaaaaa
     8281 tgtatgatta tatagaagca tttggtctta tggataagac aggtatagat ttaccaggag
     8341 aagctaaggg aatactgtat aacgaaaaaa atgtaggacc agttgaattg gctacaatat
     8401 catttggtca atctatatca gtaactccaa tacaacttat aacagctata tcatcaatag
     8461 ctaatggtgg agatttaatg caaccaagag tggtaaaatc ttatactgac aataaaggaa
     8521 atataactga aacagtaaaa ccaaaaaaag taagaagtgt tatatctaaa gaaacatcta
     8581 aaaaaatgtt agaaattgca gaatcagttg taactgaagg tggaggaaag atagcatata
     8641 taccaggtta tagacttggt ggtaaaacag gtacagctca aaaagttata gatggtaagt
     8701 atgctccagg aaagtatata tgttcatttg ttggaatagc accttgtgat gacccgcaaa
     8761 tagtagttct tgctattgtt gacgaaccaa caggagtaag tgcatttggt agtactacag
     8821 caggaccaat agtgaaagaa ataatgaatg attctttaaa atatttggga gttaaaccag
     8881 tatataaaga agaagaaaaa gctgagtatg aaaagaagca agttaaagtg ccagatgtaa
     8941 gaaatctaaa aataggagat gctgtaaagg cattggagga tgcgaagtta aaaccagact
     9001 tagatgcaga tatagaactt ccagaagata caaaggtaaa ggatatattc ccaaaacctg
     9061 gagtaaaagt taatgaagac tcaagtataa ccctatattt tgaaaactaa aaagtaacag
     9121 ataattaaca tatacccata aacatcttca aaaaaacaga aatatagtat ataattataa
     9181 agttaagagt tatcgtaggc aatgtatata taacggtata cattgccttt tgttgctaag
     9241 agaatatagc taaggtttta aaggaggagt ttaataatgg agtgcttaac aataaaagag
     9301 ttagtacttg caactaatgg gaagttaata tatggagatt ataatgactg tgtaagtgat
     9361 atagttatag atagcaggga ggcaaatgcc caaaatgcat ttgtagccat agttggagaa
     9421 aatttagatg ggcatacatt tatgaagtct gcatatgata gtggatgtaa aacttttata
     9481 aaaaatgaaa gtaatggaat aaaattagaa agttcggata taaatttaat agaggtaaaa
     9541 gatacatctt tggctctagg agatatttca aaatactata aagaaaaatt tgatattcca
     9601 tttataggtg ttacaggtag tgtgggaaaa actactacta gagatatgat ttactctgcc
     9661 atatctgcaa agttaaatat actaaaaaat gaaaaaaact taaataatca ttttggagtt
     9721 ccattgactt tatttaatct aaataaagaa catgagtgtg ctgtaataga gatgggtatg
     9781 tctggattca atgaaataaa atatttagtg gatatagtaa atcctaaaat tgcagtcata
     9841 tcgaatatag gattatcaca tgtagaaaaa ctaggttcac aagagggtat tttgaaagca
     9901 aagatggaga ttacttcaaa ctttgatgaa acaaatactt taattgtaaa tggagatgat
     9961 aagtttttat ctacattaaa agaaaaagaa catgtatata agttaaaaac atttggcttt
    10021 aataaaaaca atgatgttta ttgtgaaagt tatactatgg aagaggatag tttaacattt
    10081 atatgtgtaa taaatgggaa aaaagaggaa atatttatac caacaatagg agaacataat
    10141 atatataatg caatgtctgc tatattagtt ggtttgtgtc taaatatttc tttagattat
    10201 ataaaaaaag gtttaaaaaa ttttaaaggg acaaaaatga gactagacat aataaaaaat
    10261 gaaaaattaa caataattaa tgattcatat aatgctagtc cagattctat ggatgctgct
    10321 ttaaagatac ttggaagata taaaggtaga agggtagcga tacttggaga tatactagaa
    10381 atgggtgaaa tttcagagta tggtcataga ttagttggaa aatcatctat gaataatact
    10441 gatattataa taactatagg tgaaaattca gtgtttattg gagaagaagc aaaacaatta
    10501 ggattcaatt cagccaatat atatcacttt gagaatagag aagatgtgtt taacaagtta
    10561 aatgaattag taaaaacagg agacactatt ttagtaaaag gctcaagagg catgagatta
    10621 gaaaaaatag tcgaatatct aaataaataa gcttaaacta atgagttaat tgacaaggga
    10681 gaggagtttt atgatgttag gaataacaga gcttacgtac accgcattga ttgcgttttt
    10741 aatagtaatt ataataggac caatatttat accaatgctt agaaaattta aatttggtca
    10801 gacagttaga gatgatggac cccaaacaca tctagctaaa aacggaacac ctactatggg
    10861 tggaattata atgattgttg caattctaat aactggactt acaagagtaa aagttagtca
    10921 tgatatggca gtaggtctta tatgtattgc aggttttggt tttattggct ttttagatga
    10981 ttttataaaa ataaagctaa aaagatcact tggactaaaa gcatatcaaa aaataatcct
    11041 tcaagttgca ttatcttttt atgttgcttt ttatcagtat acatcatcat caagtgcttc
    11101 acaacttatg ataccattta cagattttgt gataaatgtt ggaatattat atataccaat
    11161 aatgatgttt ataatcgtag caatagtaaa tgctgtaaac ttgactgatg gattagatgg
    11221 attagcatca ggagtaacat taatagtttc tgtattcttt atgctatttg caagttctat
    11281 tgctggaaat acagaagtcg cagttttagc agcagcaact gttggagcat gtttaggttt
    11341 cttaggattt aattcatatc cggctagagt gtttatgggc gacacaggtt caatggcatt
    11401 aggaggtgca gttgtagcat tttcagttct aactaactca gtgcttataa tacctataat
    11461 tggaggaatt tattttgcgg aggctctatc agttttgatt caagttggat attttaaggc
    11521 aacaagaaag agattcttta agatggctcc aatacaccac cactttgaac agtgtggttg
    11581 gccagaaaca agggttgtat ttattttttg gattataaca gttgttttag cttggataag
    11641 tataatagca gtattttagg gctaggggga atgaaaaatg gacttaaaag gaaaaaaagt
    11701 tttattagta ggacttgcaa aaactggtat atctacaatt aaacatttag ataaattggg
    11761 tgcaagtgta atcgtaaatg atataaaaga tgaaaataaa ttgagaaata tacttgatga
    11821 attgaaatct ataaatgaca taaaatacat attaggacat cacccagaag atgtagatga
    11881 tatagatatg gttgtagtgt ctccaggtgt accactagac ctaccattca tattgaaatt
    11941 aaaaaattca ggcaagtata taattggtga ggtagaatta gcttttaaac tatcgaataa
    12001 tccaattttt atagggatta caggtacaaa tggaaagaca actacaacta gtttggtagg
    12061 agaaattttt tcaagagcaa aacgagatac atatgtagtt ggtaatatag gaaatcctgt
    12121 aatagatact atagaaactt caagtgaaga gtctgtgtta gtaactgaac taagcagttt
    12181 tcagcttgag agtatagatg aatttagacc taaagtaagc gcaatattaa atattacaga
    12241 ggaccattta aatagacacc atactatgga aaaatacata gaagcaaagg caaatatatt
    12301 tatgaaccaa actgttgagg atttctgtgt attaaactat gatgatgaga tagtaaaatc
    12361 tttagctgat aaatgcaatg ccaaagtaat ttacttttca agaactaaaa aagtaaatgg
    12421 aggagtatat ttagaaaata atgacataat aatagatata gatgataaaa tcaaatttct
    12481 aaataaagat gatgtaagtt tacctggagg tcataactta gaaaattgta tggcagctat
    12541 agcaatagca tatgtctgca aaattgattt agaagttata aaggatgtac ttatgacatt
    12601 taaaggagtg gaacacagac aagagtttgt aagaaattta gacaatgtaa tatatgtaaa
    12661 tgattcaaag ggaactaatc cagattccac tataaaagct atacagtctt atgatagacc
    12721 tataatactt atagcagggg ggatggataa gggaagtaat tttgatgaac ttcttgaaac
    12781 tgcaaagtca tatgttaaat cattggtctt attaggagaa actgcatcaa atatagaaaa
    12841 ttgtgctaaa aataaaggat ttaatgacat acatatagta aaagatatgg aagaagcagt
    12901 taagacttct tatgaaattt caaaaagtgg agatatagtg cttctttcac cagcttgtgc
    12961 aagttgggat atgtatgaaa gttttgaagt aagaggaaaa gacttcaaag ataatgtaaa
    13021 caatttaaaa taatctctta cctctaaact tacttaaatg gaagaatgga ggtagattag
    13081 ttggatgcct aaagaaaatt tgaaaaaaca aattgacata aggatgaaga ctgaatttga
    13141 tggagtagtg ttttacacta ctatgctttt agtatttgta ggaatagtta tggtgtttag
    13201 tgcaagtttt atacaatctt catttaaaca caatgatgcg tactattttc taaaaaagaa
    13261 tgtaatatat gctgtacttg gatttatagt tatgattatt acatcaagaa tagattatag
    13321 tttttggaag aaaaatgcta cagcaattgg agctatagca gtagtattat tattgttagt
    13381 tttgacccct ttagggatag aagcaaacgg agcaaaaaga tggttgggaa taggagcttt
    13441 aacatttcaa cctgcagaaa tcgcaaagtt tgctacaata atattaactg caaaattaat
    13501 tgaaaaaaat tatgataaaa taaaatcttt gacaaaaggt gttgtaccac ttctcgtagt
    13561 tccagggata ttttttgcgt tgataatact tcagccaaat ttgtcaacag caggtactgt
    13621 aattctagtt acttttgtaa tgatatttgt tgctggaatg gatatgaaaa ttgtatttgc
    13681 tatgataggg agtggggctg ctttatttgc tgcattagta attgctgaac cctatagact
    13741 tagtcgtgtt acatcatttt tagacccttt tcaagaccct cttggtaagg ggtatcaggt
    13801 aatacaaggt ctatatgcac taggttcagg tggattgttt ggtctaggct taggaaagag
    13861 taaacaaaag tatttttata taccagagcc acaaaatgac tttatatttg ctataatagg
    13921 agaagagtta ggattgattg gttgtataat agttattatg ctatttgtag ttttagtcta
    13981 cagatgtgta agaatagctt tgaagacttc taatgtattt gcttgtatgg ttgttatagg
    14041 tataggtgca caaattggaa tacaagcagc tttaaatata gcagttgcga catcatcaat
    14101 gccagctaca ggtgtagcac taccatttat aagttatgga ggaacttcac tcaccatctt
    14161 tatgggagct gtaggaatag tgttaaacat ctcaaagcat gtcaaaatta attaacagga
    14221 gatgatgatt tgatgaaagt tttattatca ggcggtggaa ctggagggca cgtgtatcca
    14281 gctatagcta ttgcaaacaa aataagagat gagcatccag acgctgagat aatttttgtt
    14341 gggacggaaa agggaataga gtcagaaata gttcctaagt atggatttga attaaagact
    14401 gtaacagttc aaggctttaa gcgaaaaata gatttcgata atgtaaaaag agtttttaag
    14461 ctttttaaag gtttggagca atcaagaaag attgttaaga aatttaaacc agatatagtt
    14521 ataggaactg gtggatatgt tagtggacct gttttattta atgcatctat ggggaaaata
    14581 ccagccataa tacatgagca aaattctttt cctggtgtaa ctaataagat tttatctaaa
    14641 acagttacaa aggtacttac aagttttgaa gattcgcata aaagatttcc agaggcagca
    14701 gaagataaat tagtttttac aggaaatcca gttagaaaag aaattttatt atcaagaaaa
    14761 aatattgcaa gaaagaatct atcaataagt gacgaaaaaa gaatggtact ttgctatggt
    14821 ggtagtggag gttcaagaaa aataaatgat gcaatgagac ttgtaataaa gaatatggta
    14881 aatgaagata tagcttttat atttgctaca ggcaaaagct attatgatga atttatggga
    14941 agtattagcg atataaatct taaaccatac caaaaagttg tgccttactt agaagatatg
    15001 gcaaatgcac ttgcagcaag tgatttggtt ataggtagcg caggagcaat ttcattagct
    15061 gagataacgg ctcttggaaa gccatctata ataataccta aagcttatac tgctgaaaat
    15121 catcaagagt ataatgccaa gagtatagaa aaacaagggg caggaattgc tattttagaa
    15181 aaaaatctaa ctccagagag cctaaataca gcagtattta aacttttagg agatagagaa
    15241 cttttggttg atatggcaaa tgcaagtaaa actataggta agcctgaagc catagacctt
    15301 atatatgatg agataatgaa agtatacaat tcaacacaaa agtcaacttc taaaaaaaca
    15361 aaaaaagaaa aagttattaa ggaagtaaaa gaaataaaaa aagaaacgac tccaagtata
    15421 gaaggtcaag ctaaggtaat aggaataaag aaaagataag taaatattta cccctaattt
    15481 ataatatatt agattttcta aattattata aattaggggt ttatttgtat gtatacagat
    15541 ttaaatatat aaatagtatg tagtatgcta tgtttatttt gatgaaatat tgatttattt
    15601 ataaaattta ataccttatt tggatgttat gtaataaaat gcaaaaattt gactttaaat
    15661 attataattt ttttgtagga aaaacaagct ctaaaggtgt atttattaac caaaggggtt
    15721 gattatattt gaaaaaaaga agaaagttaa atacgaataa tgtcatgata gttttagttt
    15781 ttatacttat gttatctttt tgtatatgta taattgtaaa aagtgattta tttgatgtaa
    15841 agaaaataga tgtaattgga aataagaggg tgaccaaatc aaatataatg aaagaactaa
    15901 a
//
LOCUS       DAGQVA010000092        15711 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.092, whole genome shotgun sequence.
ACCESSION   DAGQVA010000092 DAGQVA010000000
VERSION     DAGQVA010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15711
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.092"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            383..1702
                     /locus_tag="MIV85_003224"
     CDS             383..1702
                     /locus_tag="MIV85_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBY2962544.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(1777..2205)
                     /locus_tag="MIV85_003225"
     CDS             complement(1777..2205)
                     /locus_tag="MIV85_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962545.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNAVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(2296..3672)
                     /gene="hydG"
                     /locus_tag="MIV85_003226"
     CDS             complement(2296..3672)
                     /gene="hydG"
                     /locus_tag="MIV85_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBY2962546.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(3673..4758)
                     /gene="hydE"
                     /locus_tag="MIV85_003227"
     CDS             complement(3673..4758)
                     /gene="hydE"
                     /locus_tag="MIV85_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBY2962547.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNHHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(4794..6002)
                     /gene="hydF"
                     /locus_tag="MIV85_003228"
     CDS             complement(4794..6002)
                     /gene="hydF"
                     /locus_tag="MIV85_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBY2962548.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDSGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(6017..6268)
                     /locus_tag="MIV85_003229"
     CDS             complement(6017..6268)
                     /locus_tag="MIV85_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBY2962549.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(6649..7689)
                     /locus_tag="MIV85_003230"
     CDS             complement(6649..7689)
                     /locus_tag="MIV85_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBY2962550.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
     gene            8159..9319
                     /locus_tag="MIV85_003231"
     CDS             8159..9319
                     /locus_tag="MIV85_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBY2962551.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            9662..9823
                     /locus_tag="MIV85_003232"
     CDS             9662..9823
                     /locus_tag="MIV85_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962552.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            10016..10645
                     /locus_tag="MIV85_003233"
     CDS             10016..10645
                     /locus_tag="MIV85_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBY2962553.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            10885..12144
                     /locus_tag="MIV85_003234"
     CDS             10885..12144
                     /locus_tag="MIV85_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBY2962554.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            12403..13398
                     /locus_tag="MIV85_003235"
     CDS             12403..13398
                     /locus_tag="MIV85_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBY2962555.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            13644..14711
                     /locus_tag="MIV85_003236"
     CDS             13644..14711
                     /locus_tag="MIV85_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBY2962556.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYNKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            15245..>15711
                     /locus_tag="MIV85_003237"
     CDS             15245..>15711
                     /locus_tag="MIV85_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBY2962557.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRR"
BASE COUNT         5870 a         1939 c         2416 g         5486 t
ORIGIN      
        1 aagagttata aaagcttttc cacatataaa acataaaaaa caacaagagc aactagaaca
       61 ttttaaaaaa attattaatg agaaaaggta attatacaat ttaatgaaga cgaatagaat
      121 aatggtattt ataagatgat tttcagagga ctctataaaa atagaataga gtcctttatt
      181 ttttgaaaaa taatgtttat ttgataaaaa taaaatatat tgtttctgaa taacaaatat
      241 tttgaaaatt ataaaaacat atattgacaa tttgtgtcaa aaatactaac attaagtata
      301 taaagaattt tatatgagaa tatctttata aatcgcaata attttaaaac ataaatttat
      361 ttaaagaggg gatgatttgc caatgagcga gataactagt caaatgataa gtacagaaga
      421 aaaaaaatat gttgctaaaa ctcaaaagat accttattat ccagtagcat ttaaatcagg
      481 tgatggtgca atgctatatg attatgaagg taatgaatat gtagattttt tagcaagtgc
      541 aggctctgca aatgtaggtc atggtaataa ggaaatctca caagcagtta aagaacaaat
      601 ggatgatata acacaatata cacttgcata tttccatagt gatcctcctg taaaattagc
      661 tgagaagctt gtggaaatag cccctggaga taatgataaa aaagtactat acagtgcaac
      721 tggttctgct tgtatagatg ctgctataaa attagcaaga gggtatactg gaagaacaaa
      781 gataatatct atgtgtgaat cttatcatgg aagtacttat ggagctatat ctatatctgc
      841 tttaagtaca aatatgagaa gaaaaatggg tccattgtta ccagaagttt atcacttcca
      901 ttatcctgat aaaaatagaa cagctaaaga atgtttagat gagatagaat atgcttttgc
      961 acactatcta ccagcagaag aggtagctgc aatatttata gagccaattg caggagatgc
     1021 aggaataata gtgcctccag tagagtgggt acaaggttta agtaaaatat gtaaagaaaa
     1081 tggaatatta cttgtaagtg atgaaataca acaaggtatg ggaagaacag gtaagtggtt
     1141 tggtatagaa aattttggtg ttgaagcaga ccttatagtt cttggaaaat ctgttggagg
     1201 tggattacct ctaggagcag ttgttggaag aacagaaata atgcaaagtc ttgatgcacc
     1261 agcacattta tttactttag ctggaaacac aacagtatgt gtggctgctt taaaatctat
     1321 agagataatt gaaaaagaaa acttacttca aaagagtata gaaatgggag attatattaa
     1381 agcaggattt gaaaaactaa aagaaaaata cgatataatt ggagaaataa gaggcatagg
     1441 attatctata ggagttgata tagttaaagg aaaaggttct aatgaaaaac atccagatgc
     1501 tacagctaag atatgttata gatgtataca aactggatta ataatgatat tcttaggaca
     1561 atctacttta agagtgcaac cacctctagt aataactaag gagcaagtag ataaagcaat
     1621 gaacatcata gattctgcaa tagatgatta tttaaatggt agaattggtg atgaagtata
     1681 tgaagtaact caaggttggt aaaataaata ttaaatgaaa ataggagtta tctcaatttt
     1741 agaaaattat ttctgaaaag agataactct tttaagttac ccacaaataa gaaaattgtt
     1801 tgattcatta aagactatat ttcggatgtc gtttttgtga gtatcagaga cagcattacg
     1861 agaataatta cctttattcg tactatctgt taatttagtt ataattaaga tagctaaaag
     1921 aataagaatt actgtgtata aagcaataac atatggtttt cttttatatt tgtatttgtt
     1981 attgaaaaaa gaatggccat aattattttt atttacttta gatgtatttg tattcttttt
     2041 cttgttacct ttctttttat catccttttt tctattttta gggtaaggaa tgactttgtg
     2101 tgtattatca agtttgatat ttttattttt ttgaatattg ttttccaggc tagccttttt
     2161 ttctccaaat tgaatagttt tattggtatt gttgttatct ttcaatgtta atctccctcc
     2221 cttaaacttt ccctttagat aatattacta ctaacctatg gaatatacaa taaataatat
     2281 ataagtaata aaattttata ggtataaatc tctttctcca cgctctaagg cagtcatatt
     2341 gttagatact atgtttctta tatcttctct ttctatctta cctatttctt ctgcgataag
     2401 ttttttaccc ataattttaa gttcttcatc tccataatcg attaaaaatt catttaatgt
     2461 agtaagagca tttggtgtac atacattatg gatttgtcga cttttagcta agctcatgaa
     2521 tctatcgcca gttctacctt tacgataaca agctgtacaa taactaggta tatatccatc
     2581 agtaatcagt tctttaagca cctcaacagg gcttctatgg tctccaactt cgaattgttc
     2641 tgtattgtca ccatcttcat atgctttata tcctccaaca cctgttagag aacctgcact
     2701 aatttgtgat acaccatatt ttagtaactc atttctcatt tcagcagttt ctctagtgga
     2761 cattatgatt ccagtaaaag gaacagccaa tctagttata gctactattt ttttgaacat
     2821 atcgtcagaa actaagtgag gaaaatcttc taagctcata ccttcagctt ttttcaatct
     2881 agggaaagat atagtatgga aacctacacc aaatttttcc tctaagtgtt cgttgtgcat
     2941 cataagtcct agaacttcaa atttagggtc agataaacca aataaaactc ctgcaccaac
     3001 atcatcaaca ccagcttcca tagctctatc aaaagctgtt aaatggtaat aatagtcatt
     3061 ttttatagat tgaccatgca tttttataaa tgttggtttg tgataagttt cttggaataa
     3121 tatataagtt cctattcctt tttcttttag taatttatac tcatctacac ttgtagctgc
     3181 tatgttaacg tttacccttc ttatatttcc gttttcatta tatgttgaat aaattgcatc
     3241 taagcaatct aagatgtaat ttatatcaca atttttaggg tcttcaccag cttctagagc
     3301 aagtctttta tgacccattt tttctaatat tttaacctct tcctttatct cttccatggt
     3361 aagttttttt cttttaaatt tgttgcattt actaaaaccg caataaacac attcatttac
     3421 acagtagttt gatacataaa gaggggcaaa taaaaccact ctattaccat atatttcatt
     3481 ttttatttgc ccagctatac taaataatct atctagttgt tttttatctt ctacttcaag
     3541 aagtgtagct atatctttat aactaagttt ttcccttcta tcagccttat caagtacctt
     3601 ttcaatatca tcagaagttg aattttttgc atcttctaat aaagaattaa taagttcatg
     3661 gtttatgaac atttacaaac gcctccattc aatattatca ccgcgagaat agtcaacttc
     3721 aagtcctaat gacttgatgt tttcttctaa actttggtga tattcacaag cttcttgacc
     3781 agtaaaggct ttgttatcgt aaagagaata ttgttttcta aattcttgag gagaaaggtt
     3841 tggcataatt acattgcaac cagctaaaag acctgcattt ctaccactag ggtttataga
     3901 tgccaaggct gttgtagcgg gtaataaaac ttttggaagt agaagtcttg taattgaaag
     3961 cataagtaat gtcttctcta aatctccatg tttataatcc ttaaaaattg tatcatggtg
     4021 tggaataaaa ggtcctattc caaccatatg atgatttaac tcttttaggt ataataaatc
     4081 acgaacaagg tcttcgttgt tctgaaatgg tgattcaacc ataaatccag cacctacctg
     4141 ataaccaatt tctttaaggt tttttaggca ttcttttcta gttctaagct caatgtttgg
     4201 cggatgtaat tttttataat gactgtctgt agcagtttca tgtcttaaaa gatatctatc
     4261 tgcaccacat aaaaagtatt ttttatacga atcataactc ttttctccta gtgatagagt
     4321 tatggcacaa tcctcatatt tattttttat acttgaaaca atttcacata ttttatcatc
     4381 agtaaaatat gcatcttcac caccttgcaa aacgaatgtt ctgtatccta ttttataacc
     4441 tatatcacaa cattcaagta tttcatcaag tgaaagcctg tatcttatga tatttttatt
     4501 agaagattgt attccacaat agtagcaatt atttttacaa tagtttgtaa gctctataag
     4561 tcctctcaag tagactctat ttccataatg tttatttctc atgtcgctag cttgtttata
     4621 aagatagttt cttaaatttt gttcgaagtt atattcctca ttgtcgatat tttctattaa
     4681 atatagtagt tcatcaaaac ttaatgaatt aatgctgtaa agtttatcta taaagtattt
     4741 aatcttattt ttagtcatat tcaaatatat aattattaag tatagttaaa tttttaataa
     4801 ttgaaaagtt caagtgatct ttccaaaata ccttttacat atgctattaa gataccatag
     4861 tttacaatag gtacattgaa agattttgcc ttttctattc tagataacat tccagctcta
     4921 ttcatcatac aagctccaca gtgaactaca agggcatatt tatttatatc ttcagtgaag
     4981 gatactccag aactaaattc aaaagtaatg tttttgccag ttttctttct aatcatatta
     5041 ggaattttta ctgttccaat atcatcagtt tgtctatgat gggtacatcc ttcggccatc
     5101 aagattttat caccatcttt taaattttct aaagcataag cgccattaat caattcttta
     5161 aggtctccct tttgtctagc aaacaatata gaaaaagatg taagaggaat atcttttggt
     5221 gtatctttat ctacttgtgg aaatacttga gagtcagtaa taacaagttt tggttttttg
     5281 cctaaattag atagagtttc ttttaaacta tcttcttttg taactataga aattgcacca
     5341 ctatccaaaa tatctcttat aacttgctgt tgaggaagta taagtctacc ttttggagct
     5401 gctttatcta ttggaacaac taaaacaact aaatcatttg gttcaattaa atctgatacc
     5461 aatttgaact cagtgctatc cttaggcaaa acttttatta tttcattttt taaattttca
     5521 attccaattt tatctgttga tgagacagaa acaactggac atttaacttt atttttagtt
     5581 aagtttaaaa tttctgattg attcttaata gtatcaattt tgttgagaat tagaatatga
     5641 gggatattct tatcattaaa cttttcaatt agtgacaaat cttcttgtga tataccaatc
     5701 tggcaatcca ctactagtaa agctatgtct gtcttttcta aaacatctag tgatttacct
     5761 attctaagtt caccaagttc accaacatca tcaagaccag cagtatctat aagaacacaa
     5821 ggtcctatag gaaggatttc cattggtcta aatactgggt ctgtagtagt tccagcaata
     5881 tctgagacta ttgcagcact ttgatttgtt atagcattta ttatgctaga tttacctgca
     5941 tttcttttac caaagagacc tatatgtact cttaccgatt gtggagtaga atttagactc
     6001 atttgtactc accaccttaa acttcttttt ttgatatact agtttttaca gatacatgag
     6061 gtatgttgcc taatttacca gtcaaactat taatagtatc catttcgcca acaactgcta
     6121 tacatacgat tgagacacct tcttcttcgc aaggaatgcc cattcttcct ttaataatac
     6181 ctttaaaacc tgatacaacc tcattgaatt taaattgaca ttcttttggc tcttccaaaa
     6241 tagcacttat aactgcaacc tttttcataa atatcctcct aactcagaaa atatgtctta
     6301 aacaaatcca aaatcaaaaa acttttcttt gtaaagaaaa gtttctacaa aagaaaagtt
     6361 attaattaca caagtataat gtgctatatt aaactatttc cttacagatt agataactct
     6421 tttctggtag ggttagcttg taaaaattta atttaacaac aagtaactga agaaaatttt
     6481 tatacaattt atataaatta taataaaaat taactaaaga aaattgaagt tacttatata
     6541 atagtagtaa attgaaatta agtctataga aaaaccaatt tttgtataaa aataaaaatt
     6601 aaagttaatt atttgttaag aattgacttt ggtaaaatat ataattaatt attctttaag
     6661 catataattt ataagtaatt ttagtgtatt ttcaatagct tctatatgtg ttctttcata
     6721 atggtgacta ttgtttgttc caggaccaac acatgctatt tgaacatctt ctccccaacg
     6781 aatagcttct gaagcatctg aaccatagaa agtaaataca tcgacagcgt agtctaaatt
     6841 attgtcttct gcaacatcga caagcttgtt tcttaaatta aaatcatata atgataaatt
     6901 atcttttgca actatagtta caccatgttc actagatgtt tgacttggtc cagtaggtgc
     6961 tatatctatt gctacaaatt cttttgtttt ttcaggtaaa catttagaaa caccatgtcc
     7021 aatttcttca taattactta tataaaagtt agtagtatgc ttaggtgtta aattgttttc
     7081 tttaaaatat ctacatattt caagaaccat tgctacagct gatttattat ctatatatct
     7141 agattttata aaaccagatt ctgtagcctc aaatctatgg tctaggcata caaaatcccc
     7201 aacacttatt cctaaatcta atacatcttg ctttgtaaat actttttcat caagtctaat
     7261 aatcattgtt tcttcatttc tttcagtggc agcttttgtt tgaccatata tatgagtaga
     7321 agcatactta aatacaacac ttcctctgat ttttttacct tttctagtta taacagtaca
     7381 gttttctccc tctatagctg cccaacatcc accaccaact ttatggtatt taagagtacc
     7441 atcagatgat atttctttta ctatagctcc aagtgtatcc atatgtgcag atattgttat
     7501 ttgatttgaa tcatcttcac caggaagagt agctataagt gcaccttttt ttgtaagaat
     7561 agtgtcaaga cctaaatttt caaaatcttt tttgatttct aaaactgcat tttcagtata
     7621 tccagctggg cttggaatgt ccaaatattt tttcattaaa tttatagtat tagttaaatt
     7681 taaattcata ttgtttcctc ctaaataaat atatttatac aaattataac ataaatacaa
     7741 atgttctgaa aactaaaatt aaaagaatag aatctaaaca tatttaaaaa aaaagtatat
     7801 aaaataaatt tgatttatat tatatagatt taaagtaaaa atagttttat ttaataatta
     7861 ataaaaataa atacaaaaca aaataaataa ataataaaat atttagttta attatcttta
     7921 caaataaaaa ttttagtaat aaaataattg ttgaaaaaga ttttaaattc agattattca
     7981 tttctaaagt aattaatgtg caaatcttta ttaatatatg tcaatagtta ggtatatatg
     8041 tatttaatta gcatgatata gataaaagta tttattttaa ttgtctatta tctgaaaaag
     8101 tctttactta gaaatcataa aaatcaaatt aattaggaaa agaaagggtg tgtataatgt
     8161 gattgagact ggatttgtat attgtagttt cttggttgta ttcgtaggtg taattttttt
     8221 tatggttgat aaattgaaat ggaaggtatt tgatgttatt aatccaatgc ttttaatata
     8281 cttaggttca gctatacttg gatcatttgg tttatttgca cagaatgaag atgttggaac
     8341 gtatcaaaac ataataacag tgaacttcct tccattaatg ttagtgtttt tgttaattca
     8401 atgtgattta agaaaaatat taaagatggg gcctaaaatg ttattatcat ttttctgtgc
     8461 tacatttaca tttatgcttg gatttgttat agcattcata atttttaaaa attcaatggg
     8521 tgcagattca tggaaaattc ttggggcagc atctggttca tggataggtg gctcatcaaa
     8581 tatgattgca gcagcgaatg ctctaggagt tgcagaagaa ggacttagtt atgcaatact
     8641 tatgggttct ataggatata cagtatggat gtctgtttgt ctaatgtctg tgaaatttgg
     8701 acctaaattt aacaaatgga caaagtgcga tacaagtttt atagatgagg ttacatcaaa
     8761 acttgaaaaa gaaaataaag ataatacagc acctacgttt gtagaactta tgattttact
     8821 ttctgttggg tttggagttg cgtcttttgc acaaattgta tccaagatac ttccaacttc
     8881 aggtatactt aatgaaacta tgtgggtagt acttgttgca tctacagtat caatattatt
     8941 gggtatgaca aaaatatcaa agcttaaagg gagtacactg gtaggaaatg tgtttatgta
     9001 tttactcctt gcagctacag gtagtaaagc aaatttcttt ggattgtcag aagcacctgt
     9061 ttacataatg tttggattgg tagtagtcct tgtacatgct atttcattta tagggcttgc
     9121 taaactattt aaacttgatt tatttacttg tgaagtagga agtatagcta atataggagg
     9181 agtaactaca gctccaatga ttgctggggt tcacaatcct gtattaatac cagtaggtgt
     9241 acttatgggg cttctaggaa atattatagg gacttattgt gctcttatgg taactcaaat
     9301 attacatatg ttagcttaat aaaaatatgg tataaaatta ataatttaaa taagaaaagt
     9361 catttcaatt taagcagaag cttttactga aatggctttt tttgtttgac aagataatct
     9421 atttcaagaa gatgttttga catatttagt gtataatatt gtaaaattta ctaaaaacga
     9481 gatatattta atttttatat tgaatcgaac gtctgtatga tgtataataa atatacagaa
     9541 cgaatgtttg cagaacgggt gttttttgaa tttattttaa taatttatga atatatatca
     9601 gaatgcataa atatatttaa atataaagat taaaaagaat ttaaaggagt gttgataact
     9661 tatgataatt ccatcaagaa gaatacaaga tataacatta acaaatttaa aaaatggtga
     9721 agtaacttta attgaattgg atgaaatata caagaagatg ggatttttat ttgttgttag
     9781 tgaaggcaaa ttgaaaaaga taaaaaagga gaatcatcat tagaaatgaa tgaaataata
     9841 aatattataa tagtttataa aacctaactt atgtagaata taaatactta agttaggttt
     9901 ttttgtgata aagtttataa gtactcaatt ttataagata aataatggtt ttaagtgaaa
     9961 agtaaataag tttaaatttt agtaagtatt atattgcata agaggtgata ttattatgaa
    10021 aatagtaacc tacaatattc ataaaggtat ggattcaaat aatagattaa ctctaactaa
    10081 aatggggtta tatttaaaac aattggattg tgatgtaatt tgtttgcaag aagtattata
    10141 tcctcaattt ttagctttaa aagctgtttt aaatatggat ggtgtctttg cgacaaatgt
    10201 aaaaaaagta aatatgatat atggtatttg tacatttaca acatctaaaa tgttaaacag
    10261 taatcatttt ttcttaacta gcaaaaaaga acaacgggga gctctttgta taactataga
    10321 tgcatatgga agaattataa atgtaataaa tactcacttg ggacttgata ggcaggagag
    10381 agcaaaacaa ttagacgaaa taatagacta taggaacaga ttagtgggga tagttatttt
    10441 atgtggtgat tttaatgaga aaaatgtctt tttaagtatg tttaatgata tggctatttc
    10501 actaaacaag tcttacttac caacatttga aaaatcaaac tctagaatag attacatttt
    10561 tgttaataaa aatactgaac taaaaggata cacagtagaa aaaatttacc tgtcagacca
    10621 ttatcctgta ataggttaca tttaaatttc aatataaatg aaattagttg ttataaaata
    10681 aacaattttt ttgttaagaa atagtaaaag aaatataata aaaaatatca aaaataaaac
    10741 taattataag acataaattt acaataaagt tacatttgat taaattcctt gtttaacaaa
    10801 agctattcaa atataatcta aggtagtttt gaaatgggaa ctctattatg caaatttaag
    10861 ctagtgttaa aatgaggtga agttatgggc agaagaacaa caagagtttc aagattaggt
    10921 aaagaaaaaa aacgaagtgt tttaattgta ttggcagctt tagttctaat aatgggtgga
    10981 tttacttatt tttttaacag taaatttctg tacaatggga aaatcgctaa aaatgtatat
    11041 atagaaggag taaatgtatc tgatatgact aaagcagagg cattaaaagc tataacagat
    11101 aagtatactc cagaagattt aaatcttgct tatgatggga aaaaatatac aatatcacca
    11161 aaagatattg atttaaaata tgatacagaa gatgttgtaa aagatgctta tgaaagtaca
    11221 aaaaaagggt cctattttca aaacttaaaa aaatatattg atataagagt gaataaggca
    11281 aatatgaaga taaaagctga atatgatgag gcaaaactta gttccaaagt gtcttctata
    11341 gcagatagta taaatgttaa gatgaaaaat gcttctatta gtgttggaag tggtggacta
    11401 agttatacag actctgttgt aggtagagaa tttgatttgg cagcaaataa agagtctata
    11461 tataatatga taaaaaataa agagcataaa actttagaac ttaaagtaaa tcttcaaaaa
    11521 ccagatataa caactgaaca agtaaaaact gtaaattctg ttataggtca atattcaact
    11581 acttattcac aagctgtaga gggtaggtca tataatgtag gattatcagc aagaaaaact
    11641 agtgatgtat tattaatgcc aggtgaagaa ttttcataca ataaacttac aggacctagt
    11701 aataaagcaa atggttacaa agatgcacct gttatagttt atggtaagct agaacaatca
    11761 gcaggaggag gtgtttgtca aacatcttca acagtttata atgcggctct tctttcgggt
    11821 atggagataa ctcaagttac aaatcattca tctgcatcta cttatgtgcc taaagggaga
    11881 gatgctactg tgagcgatgg aggattaaac ttaaagttta aaaatccata taagcatcct
    11941 gtatatatta aaaattatgc aggtggagga agtgtatcat cagtaatcta tggtaattct
    12001 ggtgacaaac caaatatatc tatagaggta aaacaaactg gtcagaataa atattctaca
    12061 tatcgaatat ttaaagattc aagtggaaag gtcataaaaa aagaacatat atcaaatagt
    12121 tcttataaag aattaaaaaa atagataatt ttttagagaa atatttgtaa tataaaaggg
    12181 agtgtctcaa aatgaacttt ttagtttatg aggcactctt tttctgtgaa atcaaatata
    12241 ttttcatcat ttcaacaata caaaagaagc gtatctctat tttgagacag ccttttttgt
    12301 aaaaattaac actattagtt cttgttttaa tattacaatc attaatatat agaaaatatt
    12361 cctatatatt ggtataattg taaatagatt tagttatata aaatgtatga ggaggtgaca
    12421 tggttgaatt ttataggcaa tagatatgag gtagtaaatt ctgatgacgt tttagaaatt
    12481 aacaaaatct ataaagctag agatgttttt tacaggaaaa atgtgttaat aaaagttata
    12541 aagcacaata attatatctg tgaagatttt gtttcaaatt taattgatga aagtactgct
    12601 ttagatgaga taaactctcc ttatatacta aaaataatag atgttgggat tcactgtaca
    12661 gaagaaacaa cattatatta tgttgtaagt gaagacttta atggtatcgg actagatgaa
    12721 ttaattctag gtaattatct tcatttagaa gcaattgtaa acataatgat acaagtttta
    12781 aaagctttag aaatgataca taggaatcat tcatatcatg gtagtttaaa atcgagtagt
    12841 ataatagtag atacagaata caatataaaa atttgtgatt ttggaattac aaaagcaaat
    12901 aatggggtta atacaagaag ctatggaaac aggagatatt tatgcccaca tcaactatgt
    12961 ataaattata ctgataaaga aagtgatttt tttgcaacag gtcttattct atttgaatct
    13021 atatttaaaa aattgccttt tggagaatca aattcagaag aaaaaatgct acaatctatt
    13081 gataagggat tagattggaa tagtataaaa gcaattaatg gaaatactga acttataaat
    13141 gttataaaaa ggcttcttgg aagaaataat aagtatacta gagccaatga tattattatt
    13201 gatttaagta aagtaatgta tgaaaaagca tatatagaag ttgaagatga gaaagaagaa
    13261 gagcagaaac aagacaaagt tatacaagtt aaaaaagaat ataaaagtaa aatgagaaaa
    13321 aaattacata aaaaacttgt tgttgccggt ctagctatag tcatgatttc aatgattatt
    13381 attagttcca taatataaaa attgtatatt aagtatttta aaatcaatgt ctataaagga
    13441 tatacataga aattttagtg tagtcttaaa ttatgaaagg aagtggttat tatgttaaca
    13501 aaaaataatg aggtattaaa cgtctaggag tattttaaca aatagccacc tgcttttaca
    13561 gtttagaata aaaaagctgt ggctaaaggt cacagctttt tgctactttt taaaggcagg
    13621 agaatattaa aaaggagcaa attatgagca atataaaaat aatagcaagt aataaatgtt
    13681 ggattgaaga tatagcaagg aaacaacttg aagatatttc aaagttaaat ggaattttaa
    13741 gagtagtagg attacctgac ttacatgcag gtaaaatacc tgtaggttta gcagttgaga
    13801 ctaaaaatat tatttatcca catataattg gaaatgatat aggatgcgga atgactttat
    13861 ttaaaactgg ggttctaaaa aagaaattta aaaaagacaa atggattaag tcacttagta
    13921 agattaaaga tttgtccgat atagaaataa aaaacacata taaagaagaa tgtccaattt
    13981 taaatttagg aactataggg agtggaaatc attttgtaga aattcaatgt ataagtgaaa
    14041 tttataataa agaacaattt gaacaattaa aattttcatc tgatgatatt atgatgttag
    14101 ttcactgtgg gtcaagaaat tatggagaag atattttaaa aaaattttat gataaagatg
    14161 gacttgaagt tgaaagtgag aaagctatag attatattaa aaaacatgat aatgctttaa
    14221 tgtgggcaga gcgtaatcgt gaagctatca gtaaaaaaat tatgcagtca ataggtacat
    14281 ctggagatgt tgaaacaata ttctctataa atcataattt tatagagaaa agggaagata
    14341 aatttataca tagaaaaggt gctgtttcaa gtgaaagagg agctgtgatt ataccaggtt
    14401 caagaggcag tctatcatat atagttatgc ctactgaaaa tacagagata tctttatatt
    14461 ctctatcaca tggagcaggt agaaaatggt ctcgttcagt ttgtaaatct cgccttaaaa
    14521 gtaagtataa taaagatact ataaaacaaa ctaaatttaa aagtcagatt atatgtaatg
    14581 atgtaaattt attatttcaa gaagctccag aggcatataa gaatatagag cagattattg
    14641 aaagtttgat agaatatgaa cttattcaag tagtggcaac tatgaagcca ttgattactt
    14701 ataaaggata atttttaaag ttaaaaaaga ttaaaattat attataaata gctaatttta
    14761 tggaacattt aaaagtgttt tattattagc tattttttta ttttgtagag acgataattt
    14821 atagagctaa attctttgat atataatgat tacaaagtta gactgtattg gaaaatgcac
    14881 atacatgaat tgatgacaat ataagtgatt cccaaatata aatgaaagta taagcttatt
    14941 ttcactataa aaattttcac tgtacaaaaa cattaatgac attattttta ttgacataaa
    15001 tatataattt atggaataat attagaagca ctgatataag tgtttaaata agaatagaaa
    15061 aggagaagtg ttttatgaaa aaaaatacta acattaatga gtccggagtt aaacttctta
    15121 ataaataagg agtttgatat ataataactc cttatttatt aagttgttcg caaaataact
    15181 attatcaaag taaatgatag ggtgatttaa aagacgataa cttataaata aaggagaaaa
    15241 aataatgaat agtaatacat ttgaaagatt acaactaaat gaagttaaag aattaataaa
    15301 aatacattgt gtaagttcac taggaaaaaa tttaatagat aaattaactc ctagtgggaa
    15361 tattggagta gtaagaagga aattagcaga aaataaagaa gctagaaaga taattgaaaa
    15421 tagtaatcac ataccacttg aaggattgtt taatgcaggt tctacaatag ataaaattga
    15481 aaaaggaatg ataatagaac ctgttgaact tgtaaatatt gaagattttt taagaggttg
    15541 taggaagatg aaagctttta tgttagaaaa agaattttat tcacctacat taagttctta
    15601 tgccttaaat ataacagaat gtaaaagtat agaagatgag ataaattact gtataaaatc
    15661 taataaagtt gattctaatg ctagtaaaga attaaaaaag ataagacgaa a
//
LOCUS       DAGQVA010000093        15372 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.093, whole genome shotgun sequence.
ACCESSION   DAGQVA010000093 DAGQVA010000000
VERSION     DAGQVA010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15372
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.093"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            405..1055
                     /locus_tag="MIV85_003238"
     CDS             405..1055
                     /locus_tag="MIV85_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBY2962558.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEYIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            1258..1929
                     /locus_tag="MIV85_003239"
     CDS             1258..1929
                     /locus_tag="MIV85_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962559.1"
                     /translation="MAKILVVEDEKRMQNIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            1926..3056
                     /locus_tag="MIV85_003240"
     CDS             1926..3056
                     /locus_tag="MIV85_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2962560.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLIDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3487..4332
                     /locus_tag="MIV85_003241"
     CDS             3487..4332
                     /locus_tag="MIV85_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962561.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4332..5360
                     /locus_tag="MIV85_003242"
     CDS             4332..5360
                     /locus_tag="MIV85_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962562.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5363..6376
                     /locus_tag="MIV85_003243"
     CDS             5363..6376
                     /locus_tag="MIV85_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962563.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVF
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(6893..8143)
                     /gene="cme"
                     /locus_tag="MIV85_003244"
     CDS             complement(6893..8143)
                     /gene="cme"
                     /locus_tag="MIV85_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBY2962564.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8229..8975)
                     /locus_tag="MIV85_003245"
     CDS             complement(8229..8975)
                     /locus_tag="MIV85_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2962565.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSSPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9109..10131)
                     /locus_tag="MIV85_003246"
     CDS             complement(9109..10131)
                     /locus_tag="MIV85_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBY2962566.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10131..12551)
                     /locus_tag="MIV85_003247"
     CDS             complement(10131..12551)
                     /locus_tag="MIV85_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBY2962567.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSLKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLEQGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(12637..13557)
                     /locus_tag="MIV85_003248"
     CDS             complement(12637..13557)
                     /locus_tag="MIV85_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2962568.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            14147..15073
                     /locus_tag="MIV85_003249"
     CDS             14147..15073
                     /locus_tag="MIV85_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBY2962569.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
BASE COUNT         5547 a         1920 c         2419 g         5486 t
ORIGIN      
        1 tatatttaca ttaggagttt tctatactat aattatttaa aactaaatat aaatgttgga
       61 attatttagg acttgaaatt gtctaaaaat aaatacaagt gatgaagagg tgatgtgatg
      121 agattagata tggatagtat gttatatgta ctaatttata tgacattatt ggtatctatc
      181 attggaagta tattttattt ttgtaaagac ctcttaaatc ataaaattaa gtatgtttta
      241 ataagagaca tatttgtaaa tagaattaca tattctgaag aacgactgcc taaacagtat
      301 atagtttttc agaaatatga tatttggagg tattgtagtt tgttttaatt tgaaatgaat
      361 ctattataaa ttctaaagtt taaaaataaa aaggagagaa taaaatggat ttcatttcaa
      421 gtatattgca aggattatta agtatattat ttaattttac aggtgatttt ggaatttcta
      481 ttgtacttat aactttaata gttaaattag tacttatgcc actatcatta aaacaaagat
      541 tttctgtaaa aaaacagcaa gaattagctg aaaaaatgga atatataaaa gaaaagtata
      601 agaatgatac taaagaattg gaaaagcaaa tacaagtaag ttctgtagaa agtatgaaga
      661 gtatgctggg atgtcttata gttttggttc aaatgccagt agtatatgct ttatatcatg
      721 tatgtttaga tatgacaaag gaatttacaa caattataat tccatggatt gctaatttag
      781 gtacatttga taatttgttt atattacctt gtatatatac attaattatg ttagcttcaa
      841 atttagtgaa ttatatacca tatttaaaaa taaattctca agtaaagttt aacaaacaaa
      901 tggctgtggt gactaccata acaagtctta tactaactgt tagaactcca gtagccatag
      961 gtctgtactt tataacaagt gcaatttatt cattaattga agatatttgc tttagaatat
     1021 attttaatcg aaaaaataga atagtgacaa aataatataa ttattattag aaatatttta
     1081 gcctgctaac atagaaaaag ttagtaggct atttttatct atgatatcaa ttccattaag
     1141 aatagtctaa aaaatactat caaaatgcta taaaaaatac tataaaaaaa tagttgaaaa
     1201 ataaataaat taatataaac taaaataaag cctacaaaaa agaggtgata aatagaaatg
     1261 gctaaaatac tagttgtaga agatgaaaaa agaatgcaaa atattattgt agaatatatg
     1321 caaaagggag gatatacttg tataactgct gatgatggag tcgaggcact tacaatatta
     1381 aagagcaaca atatagattt aatgatattg gatattatga tgccgtattt agatggattt
     1441 tcagtgtgta gagtttcacg tgaaatgact aatataccta ttattatatt gacagctaaa
     1501 ggtgaagagg aggataaatt aaagggttat gaatatggcg cagatgatta tataacaaaa
     1561 ccatttagcc caaaagtact tttagcaaaa gttaatgctt tgttacgtag atacactact
     1621 gatattccca aaaattcatt gagtttagga aagattttta ttatggtagc atcaagacaa
     1681 gtgtatgtag aagataaatt gattgattta acatataaag aatttgaatt attgcgttta
     1741 tttatggaaa accctaatca agttttttcc agagagaaac ttttaaattg tatatgggga
     1801 tatgattttg aaggaaacac acgaactgta gatacacata taaaaacctt acgcaaaaag
     1861 cttggtagtg aaggacacca tatagttaca ttaattcgtt caggatataa gtttgaggtt
     1921 aaggaatgaa tagtttaaga aagattatag aaaaactgaa aaatgtagat atttcaaatt
     1981 ggattaaaca aaattttgga ctatattcag ttagaaaaaa agtgttttta ctttctaaat
     2041 tatcaggagc gttaattata ttattttatc tggttgttga agaattttcg ataaactcta
     2101 aatttgaatt ttggatttgg tttataatac tggttatatt tattatgagt attgatttct
     2161 tattgggaaa atttatttca gaaccaatca catctataaa taaatctgca aaaagtatgt
     2221 cccaacttga tttttctaat ccatgtactg taaatactaa tgatgaattt ggagaacttt
     2281 ctaggagcct gaatacaatg tctacaaatc tacaacaggc attatcagac ctagaaagtg
     2341 caaatattca acttgaaaag gatgtaaata aggaaagaat gctattggaa caaagaaagg
     2401 agttggtaga tacaatttca catgaaatga agactccact tggcattata cgtgcgtata
     2461 cagaggggct tatagatgaa gttgatgaag aaaaaaagaa aaattatatg aatgttataa
     2521 tagaagaaac tgatagaatg aacaatatga ttgtatcatt attagactta tctgcattgg
     2581 aagcaggagt ttctaaactt aacccagagc gttttgattt tatagagttt gttgaaactg
     2641 tggcaggtcg tcttttaatt gatataccag atgccaattt ttattttaca tatgatttgc
     2701 cagagtatga agtttttgta gtggcagata aaatgagaat ggaacaagta gtagagaatc
     2761 tagttattaa tgcaaagaag catgttgtat ataatggtaa tttagattta tcgattacat
     2821 gtgaaaatgg cttgctttta tttgaaattt ataatgatgg taggtttata gagcaagatg
     2881 agatttcaaa gatttggtct aagttttatc gtagtgttca atctcagcgt acaggaggtt
     2941 caggtctagg gcttgcaatt gtttcacaaa tacttacaat gcaagggtta gaatatggag
     3001 tgaataatcg tgatagagga gtagagtttt attttatgat tccaattgat gaataattta
     3061 gtattaattt ataaattata agtatctgat gtaaaatatt tttatttgta tacgtaagta
     3121 tttaaagaga ataaaataaa aaaacttaat gaaaaagctt aatgaaaaag tctaataaaa
     3181 agcttaatga aaagcttaat aaaaagtctt gttttcctga tgaaaacaag attttttatt
     3241 aagcttttta ttatttcact tcgatttcac aagagagaca ctctgatttc accaaataga
     3301 aataaaatag gttaaataaa ttaaaaaata gaagcgtaat taaataaggt tacaaggggg
     3361 agtacttatg aaatggtata catggttgac tattatattg ataatattgc tttctattcc
     3421 gcttaaaatt aaatttataa aatggtggga tagacgacaa aaaaatgata aaggaggtta
     3481 tgatagatga taaaagtaag agagttaaaa ttttcttatg gaaaagataa acagatattg
     3541 catggactta attttgaagt aaaagaagga gaaatctttg gattccttgg acctaatggt
     3601 tcaggaaaat ccacaacaca gaaaatctta aatggtgttt taaaaggtta caatggtcac
     3661 gtatccattt ttggtaagga agttaaagca tacacagaat ctttatatca aaagattggt
     3721 gttttatttg aatttcctta tttatatacc aatttaagtg caattgataa tttagaatat
     3781 ttttcgtctt tttatcctaa aaatcaaagg agagacatat atgaactctt agatttgtta
     3841 gagtttaaga aagagtttat aaataagcct gtatcatcct actcaaaagg tatgaagcaa
     3901 cgtattagca tggcaagagc attggtaagt aatccaaagt tgttattttt agatgagcct
     3961 actagtggac ttgacccatc tggagctgta ctatttcgta agattattga agaagaacga
     4021 aaaaaaggaa caactatctt tttgactact cataatatgc tagatgcaga tttaatgtgt
     4081 aacaatgtgg cttttattgc agatggaaag attatggtaa tagataaacc caaaaattta
     4141 aaaatgaaaa atagcaataa taaagttgaa gtggaatttg tatataatgg aaatcgagat
     4201 attgaaattg tagatataca agagttagaa tctggaataa cttttaaata tgatgaaatc
     4261 ttaagtgtac attcaaaaga acctacacta gaagaagttt ttattaaata cacaggaagg
     4321 atgttagtgt aatgtattct aaatttttta ccttagtaaa aaaagatttt tggatgatga
     4381 tttatggtaa attttttgtg ctgacacttg gctctctcat actttattcg tgttatatta
     4441 attttggtta tgtaaagttt atggatgaag atagttatca caataatgta tatctatata
     4501 atccagagaa tataagcatg agtgcatctc cattaattaa tcaagtttct tctataggtg
     4561 aattaaaagc aaaacttgat gaagatacaa gtgcagtttg tattgatatg agttccagta
     4621 agccgaaagt aattttacat gaaagtatta aaggagttga caattataga gctgactatg
     4681 cattgtcatt attatcatca gaaaaagacc ataatagcaa aatatcagac aacaatgcaa
     4741 taattcaaat taatgataag gatacatctg agataaaaca aagaaaagac atgacttgtg
     4801 agattttatt ctttgaaatt gtagctattg gatttttagg gattgcctct ttattattta
     4861 aagaaaagca gatgggagta atgcgtatta ctggtatttt acctgtaaaa agaagtcttt
     4921 ttatattatc aaagatattt gcttttttta tatgtgacct atgttttaca gttcttttag
     4981 tagtatttaa tattggattt ttagaaggaa taaaaatact tccacaagta ttagttcaag
     5041 ctagtatttt atcaattatt atgtctttga ttggaatagg atgctcaatg ttattgagag
     5101 attttaagca attttctctt atatatcttg tggttgctgt attcataact acacctatat
     5161 ttctatctgc aaatacatct tttgaaatag attggattaa atatcatccc ttctatcatg
     5221 tttatagtca gcttaaaaat gcgtttttca tgaatttttc aaaagaatta gtttattttg
     5281 tagtgtgttc tttgacaata atagttctat ttttacttgt aaaatatatt tttaataaag
     5341 aattggttag ggagggataa tcttgatagg attacgttac cagttaaaga gtataaaaaa
     5401 agataaaatg tgtataattt ccttcttttt accagttgtt atggcgattt taataaattt
     5461 tatgggaaca attgatatat cttcattagg agagatacgt tttggtatag tgaaggatac
     5521 acttcctgta caaacagagc agtggttgaa gaagtatggt atggtaagtg tatatgacac
     5581 aaaaatgcat ttaatacgtg aaattaagga tattaaaacg gacacaattg gagttgttag
     5641 agatggtaaa ggaataaaaa ctgtgtttta tggaaatgag attaatgcta taaaaaatgt
     5701 tggaaagaca ttgccagaga tgtttagact aaagggtgat ttaaaagatg ttgaggttac
     5761 aatattgcct aaagatagta ttttaaaaga gtttcaaaat gtttttattg ctatgatttt
     5821 aattactgct atgtttatgg gatgcacctt taatgcaatg aatattatat cggaaaaaga
     5881 agatggaata tcatttataa atgaagtttt gccacagagt agaagtcagt atattataca
     5941 aaaagtattt ttgggtcttt tatgtgggtg tttatcttca atgataactg tatttatatg
     6001 tttggatatt tcaatattag atatgataat gatgttgtta ctcgttgtat tttcagcatt
     6061 tatttcatca cttataggtt tatttattgg aaagttgtca gaaggtctta tggtaggaat
     6121 tgtttatatt aaaatagtaa tgattttatt tataggtact cctttgttaa tatatcttct
     6181 aggggttaat accagtggta tagggaattt atgctatata atgccttcag ttgctacatt
     6241 taatggtatt atggagatta ttaatggtaa tgtcattatt atcaaagata ttgtaatttt
     6301 ggctgtacat tgtgtagtat ggtttatgat atatattatt ttagataaaa aaagaaagtt
     6361 atcttttagt agataactca gtataattat aattgggaca atttaatagg tgatttaata
     6421 tactttgtat agtgtaattt atgtagtgca atttgtatac tttaatttat gtagtgtaat
     6481 agttagtttt attttataat tattcaatat aatttagtaa gaagttcagt acaattagag
     6541 ctacttagtg gaaaacttaa taggtactta aactatataa atactttatt ttcctccatt
     6601 tgtactataa atttaattta tgatataaat ggaggtatta ttatatgatt tgataaattt
     6661 catcattata acctacaagt aaaggtatta ttatataaag ttaataaaga tagtatcaaa
     6721 atattatttg ctataaagag agggactcaa aataaagata aacctatttt tcaatgttga
     6781 aatgataaaa tatatttgat ttcatataaa aaattttctt cataaattaa aaagtccatt
     6841 ttaagcccct tcatttttaa ccagataaat cgagttaaac tatttaaata tattactcgg
     6901 attcatttga cttagatatt ccttgcttgt aaaattgttt tgaatagggg atagccaaag
     6961 caaaaaataa aagtataatc cctgctatga ttattaaatt attaatagaa attacatctg
     7021 ccattggtcc gaaaatcatc ataccaagag gaataaaacc agtatatata ataataggta
     7081 agctaagaac tctacctagc atttgtggtg ctacatgctc ttgcaacata gtcatagctg
     7141 atgcttgaat gattggaatt gaaaaattcg taaaaaacat aaatataaaa aattgccaag
     7201 cttgtgttac aagacctaga ataattgaaa aaatagcata ggataatatt gctagaaaaa
     7261 aggtcttatt tctattttta aaaccaccaa aaactcctat aatcaatcca cctaaaacca
     7321 tacctaaaaa tccaatcatt tcaataatag acaggtatat ataacccttg ccaaatgttc
     7381 gttcaataag aagtcctata agaaatcctg atggaacaca aagaagcatg aatgctccat
     7441 aagtaaaaag cacttttcta atgaacttat ctgaaaaaca gtactttatc cctgatacca
     7501 tatctgcaaa aaatgagact ttttcagttt gttttggtat atcatgttta ggaattttga
     7561 tgaatattaa taatacaata gcaataattg cagtaaatac atcaattaaa agaacttgat
     7621 ttattttatt accaaatcca agtattgcag cagctacaat aggaactata aattgtacta
     7681 tagactgtag actactattt ataccattaa aacgcattaa atgttcttct ggtacaagtt
     7741 gaggaatcat tgcgtttaca gcaggtgttt gtacaccact tcctagtgaa cgtataacag
     7801 atattactga tatggctatt aattcacttg ttgtgccatt tgatgacatc ataaatagaa
     7861 ttagaactaa tgtagatata gcaattgttg aatctgatac aattatgagt acctttcgat
     7921 tgtagtagtc tgcccataca ccagcaaaaa aagaaattat catttgaggt ataaaggagc
     7981 atacagttaa aactgttacc catacacctg atgatgtctg aagtgtgaca taccatatca
     8041 ttgccatttg tacaagtgat gagccaaata aggaaatata ttgacttgct aaaaaaagaa
     8101 tgactttttt cttccatgta gaattagtat ttttattttc catcctattc ctcctttgat
     8161 ttgtgtgttg aatttttctt gctcttaagg ataacacaca aatcaaagtc tggagttaga
     8221 gtggagggct aggaaaattg ttttttcata atttgaagat gagatttcat ggtttttgca
     8281 ttatgttcag cttctttcaa tgaagttatc agtttgtcac acactgagat aatttcgtca
     8341 tcatcttttg gagtgtcaag gacagtttta atattagtat taggactaga agataaagca
     8401 tttaacattc gtaaaatagc tgaaagagaa tagtttgcac aacgaagtgc gcttataatt
     8461 ttaagtcgtt ttatatcttc atcagtatat acacgataac cattttgttt tctttttact
     8521 tttaacaaac cattcatttc ccaatttctt aaagtatcta ttgtaacgtt taagtgttct
     8581 gcagtttctt ttctagttaa aaagagttta tttgtttctg gagtatttcc atttaaaatc
     8641 tgtgcaacaa tagtaagtgc ttcctcggca ttagattttt ctatttctaa ttgttgcaag
     8701 tattgattta caagactaat agccttatca aagtccctat tcgctgatgt tcttacaatc
     8761 tcaagggcat cttttcttaa tcccctttgt accacttcaa ttttcaaggc tgtacgagca
     8821 aatctaaatt gttctatatg aaaatcatta aagatacgat aaccattggt attacgctta
     8881 ggtttaggta ttaagtttag ttcttcatat aaacgtactg tattaggatg tacaccaatt
     8941 aaatctgcta cctctgatgt cgtgtaagtg tccattagta ttcaactcct tttagatata
     9001 tagtattagt cataataaca ccaaacaaaa gtctggtgtt ataatggagg gtttggctat
     9061 ctaagagtaa ttagtttatg aaagagtaat tagtttatga aagagtaatt aatctattat
     9121 agaagtaagt atatattttt caatgaactc ccatctatca cgaggtttaa acactatttt
     9181 agatggtatg gctattacta agtcatattg tggaatacaa caaatagcat ttcctccagt
     9241 tcccattgct gaataccaca aaacaccatc ttttttacat agccaccaca gataaccgta
     9301 ttcattacta ttcattttaa ctgattcttc aatccacgat ttagatataa tacgtttatt
     9361 attccaaata ccatcattta aatacagaaa accaaatcgc aacatatctc tagcactcaa
     9421 tgtaagtccc cagccaccta tagaataacc ctgtctatct tttgcccaac ccttaagatt
     9481 ttttccaaag aaatcttcaa aaccaaaatc tttcatatca taatctggta taactttcat
     9541 accaataggt ttaaataagt actcattagc aaattcacga gcagattttc cagtagtttt
     9601 tgttataata gctgaaagta ggtgcgttcc agctgaagaa tatttgaaag taccaatttc
     9661 gcctttttga ccaagttgat tcaaggtata ttttatccaa tctttttgtt tgcaaagtct
     9721 ttctaaagac tcagtcatat ttttaaaagg gtatggtgca gtcattgtaa gtaggtgacg
     9781 tatagttact gcttttttac atatttcaga aggactacaa gtatattcag gaaaaaaatc
     9841 aacaaccttt tggtcaacat cttttatata tcctttatct attgcaatac ctattaaggc
     9901 tgatataata ctttttgtaa ctgatgcaac atgaaaagta tcatcagcat tatatccatt
     9961 atagtacttt tcaaagacaa tttttccttt tcttgcaata attataccat ttatattgct
    10021 atattgtgag attattaaag gttcaagttg tgaaagcttt tctgaactca taccaacact
    10081 tgaagggtct actttttcaa aaattaagtc taagcaattg tttttattca ttaaagatac
    10141 ctccctgtta tagattttgg attttctttt agagtttttg gagaaccttc tgcaattata
    10201 taacctcctt tgtcaccacc ttctggacca agctcaacaa tccagtcaca aacatttaat
    10261 acatctatat catgttcaac aacaattaca gaatttccat tttcaaccaa ttcatctaat
    10321 aattgaatca acttagaagt atcatataga cttagaccag tagttggctc atccaataca
    10381 taaaggatat taccatttcg ttttttacca atttcttttg caagtttgat tctttgggat
    10441 tcaccaccac ttaaagtcgg tgtaggttgg cctaatttta tataccccat acctatttgt
    10501 tctaatacat ttaagtgtga aacaatattt ggaatatctt tgaagaaatg tacagattca
    10561 gaaacactca tatttaaaat atcatgtata tttttatttt tatatttaat agataaagat
    10621 tcatcattaa atctttttcc ctgacattca ctgcatatat ggtctatact tagattattt
    10681 cccaaccaga ccttttcata tccactacca ctacatttag gacaagcccc tttggagtta
    10741 aatgagaaat gaccagctgt aaatccttgt tctaacgatt ctggctgacc tgcaaatagt
    10801 gtacgtatct tatcccatat accaatataa gaagcaggag ttgagttcat atttttgcct
    10861 ataggagatt gagatatctc tgaatatcca gaaatatgtt tagtaccaat cagtctatct
    10921 gcaatagttt caacaactgc ataatcgtct tcctcaccta tttcactctc tgaagaattt
    10981 atttgattat tgatagtatg gttattaaat tggcttctaa gaagaggaag tagggtgtct
    11041 gatataagtg aactcttgcc actacctgat tttccagata ttccaaccat agcacccaaa
    11101 ggtaatgata cagttacatt tttaagatta tttgtatttg cattttgaat agttatacaa
    11161 ggtattttat cagtatgtgt aatgttttta ttgcttgttc tattaggcat tggatatttt
    11221 ccagatagat actgtccagt aagtgatttg tcggattgaa gtagaccttc taaatctcct
    11281 tgatatacta attgaccacc ttcaacacca gcttttggac caatatcaat aatatgttct
    11341 gccatttcaa ttgtgttttt atcatgctca actactatga ccgtattgcc taaatcttta
    11401 agtttcttta gtgattttaa gatgtctatt ttttctgatt catgcaatcc agctgttggt
    11461 tcatcaagca cataaattaa tgagtccatc tctgaatcga gatgtgaatt taaaaatagt
    11521 ctttgcattt ccccaccact caaagttgac atttctcggt ataaggatag atgacctaat
    11581 cgtgattcta ttaaatgttg agttttggat aaaatatcat ttacaagatt tgtaccaaat
    11641 gtgtttaaat taccttgatt tattaagagt ttaaggaaat catcaatttc taaaatcgtc
    11701 atttttccaa gttctccaat atgttttccg tttaaaagta ctctacgtgc ttcttcacca
    11761 attttaaaac cattgcaatc tgaacaggca gtcatagtat aaactccatt taaatcttcg
    11821 ccccttttgt aacgattgtg aaataccttt gataaagagg aacttttttt accattttca
    11881 taatgaccat agagtacttc atttcttatt tcttcaggta gttgtaagaa ttgtatgtct
    11941 aaataatcat tgaatttttt agaaaatact ctcaaatatc caggtgtaat ctttgctcta
    12001 tctaagactt gttttagggt atcatgctta tcaaggacta atttttcaat attaatctca
    12061 aaatatgcac catgtccaga gcacttcata cacattccat ctgaagagtt gtatgagaaa
    12121 taacttggtc ttaatcgttc ttcctcatat ccacaattat tgcaaattag attatcgctt
    12181 acaggagtat cacacatagt acacattatt tgaccttcca ctgaatacaa tagtgtaagc
    12241 atgttgagaa tattggttct tgtgcctact gttgaacgag gattgctctg gcgaataata
    12301 ttttgttgaa cagctatagt gggagctaaa ccttgaatat tatcaaactt atcttcacta
    12361 tcaatacctg caagtatacc taaagattgc agatattgtt tacgcccttc ctcaaataca
    12421 atgtcaaaca taaggctaga cttacctgag ccactgacac ctgttgcaac aacaagctta
    12481 tcttttggaa tagaaacatc tatattttta agattgtgta tctttgctcc attaattttt
    12541 atttctttca ttggttcacc tcattttatc aattttatca aaccgtaaaa tagggatata
    12601 ttaatcctta atacaagaat agattaggtg aggttattaa aaaggttcta taggtaaata
    12661 tatatcgacc aagtgtctat tttgagggtg attgtgtggg ttgttaagat atacttcaaa
    12721 agggaaggag gcacgtagct tataattacc atttgatagc cattcattat acataaaatc
    12781 ccacgcatca ctatattcag attttgaaat atcaaaatgt cccacaagat attttccaga
    12841 aggtattatc atattgccaa gattgtcatt ctctttgaca acaatgttat ctggaatggt
    12901 catgcaaata ctagtcctta attgatgctc ctgtgtaaat tgtggattat catgataaat
    12961 ggctaatatt tgtgtgtttt caagtccaag tagattctgc tcacttgcat atgtgaataa
    13021 ccgttctaaa agttttggga aagtactggt tagattacca tatgaaccag tatatctagt
    13081 gtaaatagta ttcatattat caagttctag aatttcaatt tcacctttaa cctctctagt
    13141 attcttacat ttaggttttg atatgcttct attgtactga gaaattttat atggttcttt
    13201 gcaattcttg ctataattgt ttctatattt tatagggctt attttatagt aatttttaaa
    13261 tgctctcgag aaaactgctg aatcagtaaa gccgaagtag tgtgcaatat cagtaacagt
    13321 catgtcagtt ctatgaataa gaaaagcagt tgcattttct agttttagcc tatttacata
    13381 ttgtgccaaa gtttcttttt ctattgcttt gaagattcta tgaaaatgaa attttgaaaa
    13441 acctgctata ttagaaagtt catcaagaga aagaggttca tgtaaatgtt cttctatata
    13501 gtcttgcact ttgcaaatac gatttagata ttctttttta cttttagcat ttgtcatata
    13561 tagccctcct tattgtgtaa aatgtgtatc aattaattta tagcaatata gtaataaaat
    13621 tttatgtttt tgtaatttat gataaataag atagcgttta attttttata attgataaaa
    13681 gatataagat gccttatatt tgtctttgca tataagtata gtcttcgtaa taattagtat
    13741 accatagtga tttattttta attgtgtatt tatataaata cacaacttat gatatggacg
    13801 aattattatg caaataagct gtaattaaat aaattgcaat ataaaccagt tgaaacataa
    13861 gttagggaaa tattatcaaa gttattactt agcataagag tatagatgga ataaaataag
    13921 attaaaaaat tacatactaa atttaataaa atttttatat taaaaataat attaagttta
    13981 ttgtttaaat aaaaaagtta aatctacact attaacttat tatacttaaa actttaaaat
    14041 gaaaatatca aagaatactt tttaataaaa ataatcattt aataagttat ttaaaaatct
    14101 aaaaacttta caacaaatta tatatttaaa ttggaggagt gggaatatga gtaatagttt
    14161 ttatcaatta aattcagcag tattatattt taatgaaaaa agagatgtaa atagaataag
    14221 gtttaatcac tatgtaatga gaaaagaaaa tatacaaaga ttaaaaggaa ctctgccaag
    14281 aggacaattt atgatgacag taaggaaagc tgcatctgac cttgatgtat ctatatctac
    14341 aataagtaga cttgtaaatg aatttataga tttaggtata ttgagattaa taagtagggg
    14401 agtaaaggga aattgttgtt ctgtatatag ttatgtttgt tctgaaagta gtaatgcaga
    14461 aattgtaaca aagaatggtg atattttcaa aaatatagag aaatacattg atgcaactat
    14521 taacaataac caaaaaacaa tgaaatataa acatagaaat gagttgttta agaacagtaa
    14581 taccaacata tacagccgta taaatcaaga gagtatagac aaagattatg atttgataat
    14641 tcatactggg tatgaaacag aaaatgagac aaagaaaaaa gaattattaa aaaataattt
    14701 aaataaaaag aatttaaata aaaatacctt tgaaaattcg gatgaagatt tgactgaaga
    14761 ttctacttac aaaaatccag aaagcataca tgaaattatt ataagaaaat taaatagtga
    14821 atcaggaaaa aattttaaag ctgatttgag tataactaag gcacttatag ataaaagatt
    14881 aaaagaaggg tatagtttag aagattttta caaggttata gaggcaaagg taagaagatg
    14941 gagatataca gatatggaaa tatatataga accaacaatt ctgtttgggt atgaatttga
    15001 gtcgtattta aatgaggaga gttctttatc tgcttgtaat tatggtgata tgtgttatga
    15061 agatatgtat tgagatattt attaagatat tagttgcttt ttagttgttt aaaatatgtt
    15121 tatgtataaa tagtgtatta aaatggagtt gtctcaaaat agagagaagt ctcttcttaa
    15181 ttgtttaaat gatgaaaata tatttgattt aatacaaagg agagtgcttt atgagttaga
    15241 agatttattt tgagacactc acttttttta atatactgga gaaatataac ccattttaca
    15301 agagtgcata gatatatata atggcataat gtggatttaa attaaaaaaa taaaataaag
    15361 ccataaatat tg
//
LOCUS       DAGQVA010000094        14967 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.094, whole genome shotgun sequence.
ACCESSION   DAGQVA010000094 DAGQVA010000000
VERSION     DAGQVA010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14967
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.094"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            29..1522
                     /locus_tag="MIV85_003250"
     CDS             29..1522
                     /locus_tag="MIV85_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBY2962570.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYNSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            1596..1829
                     /locus_tag="MIV85_003251"
     CDS             1596..1829
                     /locus_tag="MIV85_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962571.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            1985..2749
                     /locus_tag="MIV85_003252"
     CDS             1985..2749
                     /locus_tag="MIV85_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2962572.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(3034..6213)
                     /locus_tag="MIV85_003253"
     CDS             complement(3034..6213)
                     /locus_tag="MIV85_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBY2962573.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPREYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            6494..8671
                     /locus_tag="MIV85_003254"
     CDS             6494..8671
                     /locus_tag="MIV85_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBY2962574.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFTNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            8685..9107
                     /locus_tag="MIV85_003255"
     CDS             8685..9107
                     /locus_tag="MIV85_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2962575.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            9515..10318
                     /locus_tag="MIV85_003256"
     CDS             9515..10318
                     /locus_tag="MIV85_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBY2962576.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            10311..10979
                     /locus_tag="MIV85_003257"
     CDS             10311..10979
                     /locus_tag="MIV85_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBY2962577.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            11215..11877
                     /locus_tag="MIV85_003258"
     CDS             11215..11877
                     /locus_tag="MIV85_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBY2962578.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            11937..12734
                     /locus_tag="MIV85_003259"
     CDS             11937..12734
                     /locus_tag="MIV85_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2962579.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            12852..14042
                     /locus_tag="MIV85_003260"
     CDS             12852..14042
                     /locus_tag="MIV85_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2962580.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            14151..14900
                     /locus_tag="MIV85_003261"
     CDS             14151..14900
                     /locus_tag="MIV85_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBY2962581.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         5779 a         1600 c         2485 g         5103 t
ORIGIN      
        1 taagataaat ataataaggt ggtaatatat gaaatataca tttgaaaaat ttaagttaaa
       61 tgaaaagata cttaagtcat tgaagagttt aggatataat ataccttcta gagtacaaag
      121 agaagttatt ccaaaattat taaaaggtca aaacttagta gttaggtcaa aaacaggaag
      181 tggaaagaca gcaagttttg caataccttt atgcgagaat ataaatgtag attacaataa
      241 tattcaagct cttatagtgg ttccaacaag agaattagcc ttgcaagtaa aagatgagat
      301 atcagatata gggagactaa agaaggtgag atgtagtgct atatttggta aacaatctat
      361 aaaagaccaa atagctgaat tgaaacaaag ggttcatatt gttgtagcta ctccaggcag
      421 aatacttgac catataaata gaggttctat taagttggaa aatgtaaagt atttagtaat
      481 agatgaggca gataaaatgt ttaataaagg ttttgttgaa caaatggaaa aaatattatt
      541 aaatttacct aaggagaaaa tagtaagtct tttttcagct acaatagatg aagagataaa
      601 atatatatgt gaaaaatata tgctagatta cagtgttata aatatagaag aaaatgagag
      661 cgatactaat caaaaaacaa gacaaataga tgacaaaata atcaaggcaa atggaagaga
      721 gaagtacatc cttttaaaag aattaatata cagcgaaaat ccaaagagtg tgataatatt
      781 ttgtaatacc aaagagaaag tatctaaatt atataacaag atgagtaaag aaggtttttt
      841 aataagagag ttacatgcag atttatcaca agaaagaaga atttttgtaa ttaaggattt
      901 taaaaaccaa aaatttaatg tattagttag tagtgatgta gcgtccagag gaatacatat
      961 tgatgatatt tctttagtaa taaattatga tgtgccacaa gataaagaaa actatataca
     1021 tagaataggt agaactggga gaaaaggaaa tagtggaaag gcaattacta tagtaactga
     1081 aaaggatgaa aaatatatag agaatataga aacgtatata ggatataaaa taaatgaatt
     1141 aaaagatata gaaaaaagta gaattacaca tggcaaaatt ttgtttgaag aatattcaaa
     1201 aggaatccta aaaaaagtat caaagagaaa aaaagttgat aaaaattctt acaatagtaa
     1261 agatataaaa ctaaatatag aaagtgaagt tgttaaatta tatttaaatg ctggtaagaa
     1321 gaagaaaata agagttttag atatagttgg tgcatttagt aatataaaag gtataactaa
     1381 tgatgatata ggtgtaattg aagttcaaga tttatgttca tatgtagata tattaaatta
     1441 taagggagat ttgatattaa aaaaatataa ggagatacct ataaagaaaa aaatggttaa
     1501 agtgaaaaga gatatacgat aatttagtca atattgatga attgctttgt tatcgaaatg
     1561 aagttgcaaa aaacacaata gaagttgtta aggatttgaa agctgaagat atgaaacgaa
     1621 aggtctctcc aattgactta gaaaggattt tggtgactgg aggagtaata aagcatgaag
     1681 attctatttg gttgttggac ttttggggga ataaagatat tgctggaatt ttgcttatgc
     1741 ctcctactcg tcatgttata cttcatttga atgattgttg taaatggaag gaatattttc
     1801 gtacaaaaaa gaaattttac agaagttaaa ttataataaa ttagacaaac aatagataaa
     1861 ttagcaagga atgttgattt tatctacatt ctaagttata ctatttttaa gtggctaatg
     1921 gaatagtcat tttaaatata agtaataaat atatacctat agggatatta aaggggggaa
     1981 atatatggca tattttaact ataacgacaa acagtgctac tataatgaaa ttggggatgg
     2041 tacaccatta ctttttttac atggaaatac agcctcttcc aagatgttta atgatataat
     2101 cgatttttat aaagatgaat ataaagtaat attaattgat tttgtaggtc atggaaaatc
     2161 tcaaatggtc gataaatttt ctgctgactt atggtttgat gaggctatgc aagtgatatg
     2221 ttttttagaa gcaatgaact ataaaaaagt aaacataatt ggtagtagtg gaggagctct
     2281 tgttgcatta aatgttgcac ttgagagacc tgatttagtg aataaggtaa ttgcagatag
     2341 ttttgaagga gaagttcctc tagagtcatt tgtacaaaat gtgaaaatag agcgtgaagc
     2401 atctaagcaa gatgatggtg caaaagcttt ttatatttat aatcaaggag aaaactggga
     2461 aaaagttgta gataatgata cagaagctat ttttgaacat tataaaacta taggaaaatt
     2521 ttttcataag cctctagaaa ctatgcaacc agaggtgctt ttaacaggaa gtagagaaga
     2581 tgagtttgta tctctaatat ctagtgattt ttttgaaaat actttttcat tacttcttga
     2641 aaagattaaa aatggtaaaa tgtatttgtt tgataaaggt ggtcatcctg caattttatc
     2701 gaatggatta gatttttcaa atgtagcaaa gaaattttta gaggaataat ttaaccaaaa
     2761 tttataataa tgaaaactgt aaaatggatt gcaaaactta caaaagtgag tgtacatata
     2821 cttcattatt atgatgaaat agtattgtta aaacaaaata ttctaatagt caagttatta
     2881 catttgtata tgcaatatgt atagaaagag atatcattag attgtaaagt tgggattaaa
     2941 taacaatatt aaattttatt tattcagata ttttagctta actatataaa tgttagaaca
     3001 aatttatata gttaagctgt aggattaaat aatttagtta aataagttta ttatctcctc
     3061 atcagataga ctttttaata caccttcatt agaaagttct ccatttataa attgatttat
     3121 aagctctttt ttactttctt gtaattttat tattttttct tctatagtcc ctttagcaat
     3181 caattttata acttgtactg aatttttttg accaaatcta tgagctctat cactagcttg
     3241 attttctact gatggattcc accatgggtc aaagtgaatt accatgtcag cagatgtaag
     3301 atttaaacca gttccgcctg cttttaaaga tattaaaaaa acttttttat ccatactatt
     3361 attgaactca tctacaagtt caagtctttc tttggcatta gttttaccat ctatataatg
     3421 gtatttaatt ttatacttat caagttcctt acttatgttc ttaagcacag aagtaaattg
     3481 tgaaaacaat aatattttgt ggttttcgtt tatactatcc ctaagtattt ctaaacatgt
     3541 ttcaattttt gaactttttt tattgtaatc ttttactact atacttgggt ctaaacaaag
     3601 ttgtcttagt ttagttaaat aagaaaatat aactatttta tctttcttta gatttttatc
     3661 tttcatttta tcttgtatat cttttgaata tacactatat atctttttct gctctttatt
     3721 caattcaaca aaaaagtttt tttcaatctt atctggaagt tctttcataa cttgtttttt
     3781 acttcttcta agaataaaag gttttatcaa ttttttcagg tttttaacat tatcttcttt
     3841 atttataaac aattcctgaa actttgcttt actatataga tagccaggca ttataaaatc
     3901 aaatatagac cataattcta gtagattatt ttccataggt gtaccagtga gtgcaaattt
     3961 attttctgca tttatacttt ttacagactc agttactaaa gctactggat tttttatatt
     4021 ttgagcttca tctaatatac aataatcaaa ctttatttca ctatattttt ctaaatcatt
     4081 tctaagagta ccatatgttg taagtattac atcaaaattt tctaattcca taaaacattt
     4141 ttctctatct cttttatttc catgtatcaa taaaactttt atatctggag caaacttttc
     4201 aaattcattt ttccaattat aaatgagtga tgtcggtgta acaataagac tttttttatt
     4261 agataatgat aataaaaatg caatagtctg tattgtttta ccaagaccca tttcatcagc
     4321 taatatacca ccaaatttat aataatctaa aactttaaac caattgaggc catttatttg
     4381 atagtcacga aggtttgcat ttaaatttgc gggaatttct aaatttatgc tatcaaaatt
     4441 tctaaatttt tcacatatac tgtctagttc ttttttacca tctataaact ttaaattttt
     4501 actacgtatt acatcattta tatatagagc tttattttta tgaattttat tattttttga
     4561 tttatccatt atatctagat tttcaactaa ttcaaaaaaa tcttttgttt ctctttctga
     4621 taaatctata aagtttccat ctttaagttt ataaaaagta cgtttttctt gaaaagcttt
     4681 caaaatatcc ttgtactctc ttggatttat atcagatata ttaaaattaa attctaggta
     4741 attctggtta gtctgattga ttgaagcttg aattgatgaa gcgttatata tttttttcaa
     4801 tttaaacttc tcagaataat atatatctcc aaattccttt agagattcta attgtaaatc
     4861 taaaaatgta aataggtcat ggtcagttcc tttaaacaca taatgattat tttcctttgt
     4921 aaattgtgaa gaagtaagtt tattttcaat agtagcttcc ttttgtatgt tggggagcac
     4981 aaatttttta tcttcatcat catatatata ctttacatca caacatatgt tgccatcaat
     5041 catatcaaag tagaactcag atttaaaatc ttttgttata ttatttttta tgttatcatc
     5101 taaatgaact tcttgagata tagattttaa tctaggaact agcaatccta aaacatcctt
     5161 agaatcctct ttatcaaatt ttaactcttt agtctttgat aatatttgat atatttttga
     5221 ataatcatga gcttttttat gtgataataa atagatattg ccatcatata aaagtacatc
     5281 atttttttta gtaagtggaa caggtagtga atctttagaa tataagacta ttttatcttc
     5341 tatattttta aaatcaaacc ttacaggtag agtatcattt aatatctttg gatgatattc
     5401 ctctttagaa aaaataaggg taaaatcctt gtacttaata gcatttaaaa attgttttaa
     5461 agagcttgca tttatctcca taaatttttt tgaatgtgat gaagaaaagt tgtatgaaag
     5521 atttgtccca tattcttcta taatatctac taacttctca tcttcatcag caaaataatg
     5581 agtgttgggg ttgtaagtaa atttcttccc aaaatctaat tcatatccat taagttttga
     5641 atatgcaaat tcagtaatgt tttttaaaat gtacatttta tcaattccta ttttaaattc
     5701 agcaattgct ttatttgaat ccacatttat caatacatct aaattaaccc tttctctttt
     5761 agtattgtct aacaaagaaa gtaattgctt gcttaaatct aagctggttt tagaatttgt
     5821 attagaaagc ttatccttat ctgcacctaa tatatctatt agaataggag gaacatcttt
     5881 tttatttttt atttgtttta agctttttat cacaatagca actatatgct tacatataaa
     5941 aatacttttg ccctttgatt gacagtcagc gcaactacaa tcattttcaa ttatcttaaa
     6001 gtgctttata tctatagtta ttgaattaaa ataaaagcta taattatctt cagaattgac
     6061 tccaccacga aatgtcaaca ggttattttg taggtcatca atatctatgt ctatataatc
     6121 aactaattga ttagtataat attttacacc tcttgaccat cttgatggtt ctgtatttct
     6181 tcttattagt ttatatatca tatctatttt catattattc accttacctc actgtatata
     6241 ttataatcta aatgcattca atttacactc taaatttaag actaaaatta aggcagatat
     6301 gaatagcttt tatctatcac aatatatgtg taaataacaa tttactatta gatttttatt
     6361 gaattatctt ataaactatg aatgaaaaat aattatataa atagattatt aataaatata
     6421 aaatcttatt attaaaaata ttcttagaaa ttacactata taaaatataa agtatgatat
     6481 ttgaataaaa agaatgtata ataagtataa taatttgtat ttattattgg gaaaggaaaa
     6541 tgttaatatg gatagttata gacaacttaa agctaaaata ccctgtaagg aaacaggtat
     6601 agaaataaag aggactttat gtgatatttg ttctccagga gtacattgtg gaattgatgc
     6661 atatgttaaa gatggtaaag taataaaaat agaaggtaca aaagaacatc caatgaataa
     6721 agggttgtta tgtaccaaag gtctttgcaa tagagaatat atctatagag aagatagaat
     6781 aaaaacacct ctaaaaagaa ttggaaaaag aggtgaagga aaatttaaac caatatcatg
     6841 ggatgaagct tatagagaaa tagcagaaaa attaaataga gtaaaatctg agtatggagc
     6901 aaagcatgta gcttttttta cgggttatgg aaagtggtat agaccttttt tacaaaggtt
     6961 tgcatcttca tttggttcac ctaattatgg tacagaatct agttcatgtt caacatcagc
     7021 acagatggct ggaaatgttg ctactggaag aaactttaca atgcaagata tggagaatgc
     7081 aaaaacttat ttagggtggg gatttaatcc atactactct aaatttttaa atagtgtgaa
     7141 tctaataaaa ttaaaagaaa aaggtctaaa atttataatt gtagacccta gaataacacc
     7201 gacaactcaa aaactagcag atttacattt aagaattaaa cctggaactg atggagcttt
     7261 agctcttgga atggcgaatc tatttataca aaaggattta atagatagag aatacataga
     7321 aaagcatgta catggattta atgaatataa agaatatgta aaattatttg atttagatac
     7381 tgtaagtaga attacaggag tttctaaaga taatatagta aaagctgtcg agatgttgtc
     7441 acaaggtcca ttttgtataa atgaaagtgc agctccaata gttcaccatc aaaatggatt
     7501 tcaaaattat agagcaatga tgtctttatc cgctataaca ggtaattatg atagaatagg
     7561 tggaaacata ccaaaacaag attactttgc tggtaagata ggtggattcc aaacactaga
     7621 aaaagagttt gtaaaagaag ttctacctaa aaatataaat gaaagaattg gtggagaaag
     7681 atttcctcta tggaatgaaa tggtgactca atttcaagct atggatttac ctaggcaaat
     7741 agaagaaaag acaccatatg aaataagagc tttgttttgt catgggataa atgctagaat
     7801 gtttactaat tcagggagac tttttaaagc gttgaatagt gtagattttt ttgtgaatat
     7861 agatttattt atgacagata catcaaaata tgcagatata cttttacctg catgtacatc
     7921 atttgagaga gaagaatgta agagttatcc aggagggtat attacatata ccaaaaaagt
     7981 tattgataaa ttatacgatt caaaatcaga tgtagaaata ctttcagatt tagcaaatgc
     8041 tatgaatata gatgatgatt tattaaaagc aggttatgaa gcaagtataa gacatatgtt
     8101 taaaaataca tgtgtagatg tagataaact taaagaaagt gatttaccat taaaatgtaa
     8161 agattttaag ccatatatag taggttcata tacaagagaa gggtatgata ctagcacttc
     8221 taggtttgaa ttaaaatcta caattattga aaaatataaa gattttgggc tggatgcact
     8281 accaacatat agaggattta atgataatat agatgatgaa tatactcatt tattgacatc
     8341 aggagcaaga atttcaaatg cactacattc aagacttcat gacatcaaac tttcaagaat
     8401 attaaaaaat gaagctagtt gtgatatttc tagcttagat gcaaaagaat tgggtgttat
     8461 cagtggagat tatataaaaa taactactaa gataggaagt ttggatgtaa aagtcaatgt
     8521 tactgataga gtcttatata agaatataca tatgtatcat ggatatagag aagctgatat
     8581 aaatagtatt atttgtgata attttgaccc ttatagtgga ttccctgcgt atagaagttg
     8641 taagtgtaag attgaaaaaa tgaatagata aatggagaga tataatgaaa agtttattta
     8701 aatttaataa agaattatgt acagcatgtg gagcatgttt gcttgcatgt atagaccaaa
     8761 atgataataa tatagacaat ggtgaacttt ttagacatgt atttacaata gaggaaggtg
     8821 aaaatataga atatttttca ttagcatgta tacattgtaa tgagccaaaa tgtttaggtg
     8881 tatgtcctaa aaattgtttt aaaaaagaag aaggattcat tgtattagac aatcaaaact
     8941 gtatagggtg taaactttgt gaaaaagctt gtgaatatgg agccttaatt tatggaaatg
     9001 atggtaaggc aaataagtgt aatggttgta ttgagagata taagtgtggt atggattcac
     9061 cttgtgtaat ggtatgtcct acaggagcat taaaatttaa taaataaatt aaatatagag
     9121 aatgacttat acttaggtat aagatatttt tacaaaaagc tgtattgagt ttgttataat
     9181 gaaaactcaa tatagctttt ttatggatat agttggatac tataatgtga ttcttagtaa
     9241 tagttttttg ctattggaca aagactgtaa aacatattaa acttatgttg ttcaaagtcg
     9301 aagtataata taataactag aaaattggtt tatagtgcta taaaagcaaa tttagtaagg
     9361 tataaaatca gaggcaatcc tttactataa tatcaatatt tgggagttct gttattgcag
     9421 agctattaaa caattataat ggtacaagtg attcaacctt tgaaaatgta ttatataaaa
     9481 aattaaaata agattaaaaa ggagagaata aattatgaaa aaacttaaat taattattat
     9541 gtttgccttg gtatcagcac tgttagttac aggatgttca tcaggaaata ataaaaataa
     9601 agaagaacaa aaagttataa gagttgcaac atcaggaaca tattaccctt ttgcttttaa
     9661 agataaagat aaacttaaag ggtttgaagt agatttttgg gatgaatttg ctaaacgaac
     9721 taattgtaaa gttgaatggg tattaactga ttttagtgga ttatttggat tattagaagc
     9781 tgataaagca gatgttgtat ctgctcaact tactgcaaca cctgaaagag agaaaaaata
     9841 tgctttttca gatgcttata attatagtgg aacaaacatt attgttagag aagatgatac
     9901 tagtataaaa tcaatagatg atttagttgg caagaaagta ggtgtgggta ctggagcagt
     9961 agcaaatgaa atattaaaag aaaaataccc aaatgatgaa ataaaaatag taaattattc
    10021 aagtgcgact cttaaaggga attatcaaga cctagaaatg ggaagattag atgcagtagt
    10081 tgcgcaggat gttgaggctt taatagctat aaaagaacaa aaattaaatc ttaaaatgat
    10141 agaacctcca attcaatttg gtgcctgttc ttttgcgctt caaaaaaatg aaaaaggtga
    10201 aaaatggaca aaagaaatta acgaagtaat tgaagagatg tataaagatg ggactttgac
    10261 taaaatatct gaaaactggc taggaaaaga cattactaag gagcctatta atgagtaatt
    10321 ttaattttga attttgtcta agtatatttc catttttgat taaagcattg ggaataacaa
    10381 tactaatatc tattgttgca ttttttttat caatattatt aggtgtaata cttgcctttt
    10441 tcacacagac aaaatcaaaa gttttacaat acataacaag agtgtatgtt tcattcttta
    10501 gaggaacacc acttttaatt caaatatttt tcttttattt tggatttcca atgatatttt
    10561 cttttatgaa agattgttca ccttatttag caatagtaat ttgtttaggt gtaaattcat
    10621 ctgcatatat ggctgaaatt atacgagcat ctattgagag tgttgataaa ggacaacagg
    10681 aagcatgtta tgcttttggg ttaagtaaat atcagtcaat ggttaaaata attctacctc
    10741 aagcagctac atctgcagta cctcctattg taagctgtac actggacata attaaaggtt
    10801 cttctttagg tttaactata ggaatacaag atttaatggg agtagctcaa gtagaggctg
    10861 cttcaagttt taaatatttt gagatatata tgataacgat attaatttac tgggcagtat
    10921 ctataatatt gagtaatata caaagcaaag ttgaaaaaag aataagaaga gcatattaga
    10981 tttcaatatt taaaaatggg atgatataga tatattatta cttgtaaata aatttttaat
    11041 tttagaaaaa taaacttagt aatctaaatt attgagaaaa tatagtatca aaatggactg
    11101 tataatcaag ttaaaaaata gtttttctat tgaaaaaata aataaaattc tattgtaatt
    11161 taatatgcga taaagtttta taaaaaacaa cattaagcta gggggactta ttttatggct
    11221 tttaatatga aatatttttt agaattattt ccaacaataa tgaaatcgtt caatgtaact
    11281 gtgattttgg caataagttc attagtattt tcattaatta taggtacaat agtagcgtta
    11341 tcatcttatt acaaagtgaa agtattgaat caaatatgta aagtatatgt atctattttt
    11401 agaggtacac ctcttatgcc acagttattc tttttatatt ttggactagc atatatgagt
    11461 gattttgtta aaaatatgga cccagtattt gcaacatcta tagtacttag tttaaatatg
    11521 ggagcttata tgtctgaaac gataagggca tctatacttt caattgatac aggtcagata
    11581 gaagcagcat atgcaatggg attaacaaat ttacaaacaa tgaaaaggat agtgatacca
    11641 caggccgtaa gagttgcact gccatcatta ttcaataatt ttatagattt aattaaaggg
    11701 tcttctgtag cttttgttgt tggagtaaat gatataatgg gtgctgccaa atcacaagga
    11761 gcgttgagtt ttaagttttt tgaagtgtat ggagcagtta tggtaattta ctggtgtata
    11821 ataactcctt taggttgggg gcaaaaaaaa ttagaaaaga aaataagcaa ttattaagtt
    11881 attaagaaaa tacataaaag tatttttata taaaaaatgg tgtgaggaga agagatatga
    11941 taaaaagaaa tattataaaa tgtttagtgg cagttttatc gttaacgttt gtaattactg
    12001 gttgttcaaa aaaagaggaa gtaaagaatg aaaaagttat aactgtagct tcatctaatt
    12061 cagctgaccc atattcttat gttgataatg gtgagcataa gggttttgaa gttgacatgt
    12121 ggaaagagat tggtaaaaga agtggatata agataaaaat ggaaccaaca ggttttagtt
    12181 ctatatttgg tatgttagat tctggtaaag ttgatgtggc agccaacttc tttggaatgt
    12241 ctaaagaaag attagaaaaa tacgatgctt ctatacctta tggttctgat tctgtgtgta
    12301 tagctgtaaa agatggaaat aacgaaatta ataagcttga agatttaaag ggaaaagttg
    12361 tagcagtttc agaaggttct caaggtcaac aggttgcaac tagtgttaat aaagataatt
    12421 tgtttcaaga aaaggtttac ggtgatggaa ctagtggtct tcaagattta gatttgggaa
    12481 gagttagtgc atggattgat gcagagctta ctattgtggg agacgctaaa aaagctaata
    12541 tgaaagtaag agtattagat aaaaaattat cagctactaa tatagcatac ttctttaaga
    12601 aaaacgatga taaatctaaa acgataaaag aagatgtaaa caaagcaata gaagaaatgc
    12661 ttgcagatgg aacagtgaaa aaaatatctg aaaaatggtt tggaatggat gtaagtgctg
    12721 atatacaaaa ataaatactt taaaattaaa atgtaaaact gtgataacta tagataagta
    12781 tactaaattt atctatagtt atctgtgtat tacaatgtat ttagattagt ctttataaat
    12841 caaaatgagt tatggaggta ttgcaaatga ttgaaactaa aataaaatcc attgcactaa
    12901 aaaatagaga aaaaattata aaaataagac gacagataca cagtaatcca gagttagcat
    12961 ttaaagaata taaaacatct aaacttataa aagaagagct aaataaactt aatatagaat
    13021 acataaatat tgctggtaca ggagtattag ctactataaa aggaaaaaat aatggtggaa
    13081 aaactatatt actcagagcg gatatggatg ctcttccaat caaagaggaa aatgatttag
    13141 aatttaaatc aataaatgat aatatgcatg cttgtgggca tgatgcacat gtttcatggt
    13201 tgttaggaac agcaatgatt ttaaatgaca taaaagaaga attgaatgga aatgtaaaat
    13261 tactatttca acctggcgaa gaaaaaggtg gttctgatat tgtaattaaa gaaaatgtac
    13321 ttgaaggtgt ggatgcatta gcgactggtc attgttggcc aactattgag tcaggaaaaa
    13381 ttggaatcgc tagaaattgt gctatggcag cgactaatac ttttgaaata acaataattg
    13441 gcaagggtgg gcatggagca gagcctcata attgtataga cccaattgca gttggaaatg
    13501 cagtatattc atccattcaa cagatagttt caagaaaaat tgacccagtt gtacctgtag
    13561 tagtgtctgt ttgttctttt aattctggtg tttctaaaaa tataatacca gatgtatgta
    13621 cacttcaagg gactattaga gcgataagca aggaacaagt aattgaagta agtaaaattc
    13681 tagaatatat agtaaaaaat gtatgtaaag cacatggagc agattgcaaa tttgaaaaga
    13741 gtacaggagg agatgctgtt ataaatgaca aaaacatgat agagatagga agagaaagtg
    13801 cttgcaaaat acttggagct gaaaatgttg aaataattga ttttcctgca atgacaggtg
    13861 aggattttgc tatttatatg aaagaaaaac ctggtttatt tatgtatata ggtgtaggag
    13921 ataaagaaaa aaatataaat tacagattgc atagtaacaa gtttaatata gatgaaaaat
    13981 gtcttagtat agcaccttca ttattttcac aacttacagt agattattta tgtcaactat
    14041 agagtacatt cataaaaata tatttagcct atttttaaat ttaatgctag tatattaatt
    14101 ttgatgtaga acatattatt tattatattt atttaaaaag gtggataaca atgataaaag
    14161 tagaaaattt acataaaagt tttaaaggga cagaagttct taaaggtata aatttagaga
    14221 taagtcaaag tgaagtagta gctatacttg gatcatctgg aacaggtaaa tctacgttac
    14281 ttagatgttt aaattattta gttgagccta caaaaggaaa gataatgatt ggtgatgtaa
    14341 aagtagatgt agaaaaagca acaaaaaaag atataaccaa tttaagaaaa catacatcta
    14401 tggtgtttca aaattataac ttatttaaaa ataaaacagc attagaaaat gtaatggagg
    14461 cattgatagt agttcataaa aagagtaaga aagaagctag agaaatatct ttaaaattaa
    14521 tagataaagt aggtatgttg gataggaaag atttttatcc atcaaagttg tctgggggac
    14581 agcaacaaag gataggtata gcgagagcga tggcagtaaa tccaaatgta atattatttg
    14641 atgagcctac atctgcactt gacccagaac ttgttggaga agttttaagc gttataaaat
    14701 ctcttgcaaa agaaggtata acgatgctta ttgtaactca cgaaataaat tttgcaaaag
    14761 aagttgctga taaaattata tttatggata atggtgtaat agctgaagaa ggaactcctg
    14821 atgaaatatt taataatcct aaaaatgaaa gaacagcaaa atttttaaat atcattagga
    14881 aagaagaagt atttagttaa aagtgtataa attaagcatt agaagatatg taagataccc
    14941 ccattaaatt tataagttag ataataa
//
LOCUS       DAGQVA010000095        14828 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.095, whole genome shotgun sequence.
ACCESSION   DAGQVA010000095 DAGQVA010000000
VERSION     DAGQVA010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.095"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..449
                     /locus_tag="MIV85_003262"
     CDS             <1..449
                     /locus_tag="MIV85_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBY2962582.1"
                     /translation="YDIIKIPEELKFCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVS
                     RVALLISALLNKNFDLLKVACQDKLHQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAG
                     PTIMSLIKENDDSFVDNMKNYLQKLKSDWEIKELCCDSNGAVLNII"
     gene            573..1634
                     /locus_tag="MIV85_003263"
     CDS             573..1634
                     /locus_tag="MIV85_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBY2962583.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(1789..2301)
                     /locus_tag="MIV85_003264"
     CDS             complement(1789..2301)
                     /locus_tag="MIV85_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBY2962584.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            2821..3756
                     /locus_tag="MIV85_003265"
     CDS             2821..3756
                     /locus_tag="MIV85_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBY2962585.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(3848..5719)
                     /locus_tag="MIV85_003266"
     CDS             complement(3848..5719)
                     /locus_tag="MIV85_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBY2962586.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYVSLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            5909..6835
                     /locus_tag="MIV85_003267"
     CDS             5909..6835
                     /locus_tag="MIV85_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBY2962587.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            6974..7120
                     /locus_tag="MIV85_003268"
     CDS             6974..7120
                     /locus_tag="MIV85_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962588.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(7225..7749)
                     /locus_tag="MIV85_003269"
     CDS             complement(7225..7749)
                     /locus_tag="MIV85_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962589.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(7802..8026)
                     /locus_tag="MIV85_003270"
     CDS             complement(7802..8026)
                     /locus_tag="MIV85_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962590.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            8223..9347
                     /locus_tag="MIV85_003271"
     CDS             8223..9347
                     /locus_tag="MIV85_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBY2962591.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(9821..10645)
                     /locus_tag="MIV85_003272"
     CDS             complement(9821..10645)
                     /locus_tag="MIV85_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962592.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNDNIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(10993..12048)
                     /gene="ispG"
                     /locus_tag="MIV85_003273"
                     /gene_synonym="gcpE"
     CDS             complement(10993..12048)
                     /gene="ispG"
                     /locus_tag="MIV85_003273"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBY2962593.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(12231..13235)
                     /gene="rseP"
                     /locus_tag="MIV85_003274"
     CDS             complement(12231..13235)
                     /gene="rseP"
                     /locus_tag="MIV85_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBY2962594.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINAS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(13248..14402)
                     /locus_tag="MIV85_003275"
     CDS             complement(13248..14402)
                     /locus_tag="MIV85_003275"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBY2962595.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(14566..14769)
                     /locus_tag="MIV85_003276"
     CDS             complement(14566..14769)
                     /locus_tag="MIV85_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962596.1"
                     /translation="MISYAPLWKLLIDKKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         4989 a         2414 c         1674 g         5751 t
ORIGIN      
        1 attatgatat tataaaaatt cctgaagaac ttaaattttg tgcaatgata cctaatttta
       61 agttatcaac agaaaaagct agaggtgttt taccaaagga aataccatat tctgatgggg
      121 tattcaatgt tagtagagtt gctttactaa tatctgcctt actaaacaaa aactttgacc
      181 tacttaaagt agcttgtcaa gacaaattgc atcaagatta tagaggaact ctaattgaga
      241 actacaatga tattgttgaa aaatctgaac aattaaatag tattggagta tttttaagtg
      301 gagctggacc tactataatg tctttaataa aagaaaatga tgatagtttt gtggataata
      361 tgaaaaatta cctacaaaaa ctaaaatctg attgggaaat aaaagagtta tgttgcgatt
      421 ctaatggagc tgttttaaat ataatataat tatcgtcttc tatacaaaat ataactactc
      481 ttttattata atttgtagta taataattag gactaggtaa taatattaag tattataatc
      541 tagttcttta aacatgttta cattgaggag ggattatcat aaaagagtta ataattagag
      601 atttagttgc aaaagttcct ataattcaag gtggaatggg cgttggtata tctaggtcat
      661 cactagctgg tgcagttgct aagcttggtg gtgttggtgt aatttctgga gttcaaattg
      721 gatatgatga ggaagatttt gaaactaata ctataaatgc aaatttaaga gctataaaaa
      781 aacatatttc taaggccaaa gaaatctcaa atggtggtat tattggtatt aattttatgg
      841 tagctatgaa agaatatgaa acatacgtaa aggaagctgt taaagctggt gtagacctta
      901 taatatctgg agctggatta cctaataagc taccatcatt agtaaaggga agtaatgtaa
      961 aaatagcacc catagtttca actgcaaaag ctgctaatgt aattttaaaa atgtgggata
     1021 gaaaagagaa aactactgct gacttaatag ttgttgaagg tccaaaagct ggcggtcacc
     1081 ttggatactc taacgaggaa cttgataaca tagattctat agactatgat aaggaatttg
     1141 ttgaaatttt aaaggttgca aatacttatg gagaaaaatt tggtagaaac ataccagtag
     1201 ttgctgctgg tggtataact tctagtagtg atgttaaaaa atatatagat atgggtgcaa
     1261 gtggtgtaca agttggtaca agatttgttg ctacttacga atgtgatgcc catgagaact
     1321 ttaaaatggc atacataaat gctagtgaag aagatgttca tatagttaaa agtcctgtag
     1381 gtcttcctgg acgcgccata agaaacaaat ttatagaaga agttaaaata aatcgtccag
     1441 aaataaagaa gtgctataat tgtttgattc cttgtaatcc aaaagaaact ccttactgta
     1501 tttctcaagc tctaatcaat gcagttaaag gagatgttga aaattcactt ttattttgtg
     1561 gaaatgatgc ctataaaatt gataaattaa gtactgttga agatgttatc aatgaattga
     1621 tttctgaatt ataatttaaa gaaaactaaa ttaagatttt atcaagctaa ggagtttaaa
     1681 tacgttattt attaatcttt ataaacatat ttatgtcctt agcttttttg tgtcaatttc
     1741 cttttatgga aattttaatt taattagaga tagtattaac ctttataact aatcttcttt
     1801 tacaagtaca ttggttattt cagctatata taaagtatga taatcttttt gtggatacca
     1861 tcttccatct ataccttcag caataaaaca ttgaggttca agtttctgac tatacatttt
     1921 tttgcatata atagccattt tagattcttt aaaataaggt gtatcattta agtgttctat
     1981 attaaatcca atctgtgata tcttatcctc ttctctacca gatacttttc cacaatatga
     2041 aagctcttta cgaaaatctt catcaaaaaa tgtaagagaa aatttatctg tattatctat
     2101 aaattcctta gtataacgct gtggtcttat tactacaaaa gcaacatctt ttccccacat
     2161 aactccaagc cctccccagc tagcagtcat tgtattcact ttaccttcat tttctgctgt
     2221 tataagtgtc caatctttac ctatcaatcc aaatggatta tttttaatct cttctgccaa
     2281 aatttcttta aaatcactca tatctctaat aacctctcat tctcttatat ttatattcct
     2341 tttattttcg tgataaatta taaatgaagt ctagttttga aaataaaata cttttttaaa
     2401 tatattattg caaataagta aatatatata tacactctta ttttttaata tatttaataa
     2461 tttcactcag aatatatata ttctttactc aaattaaata taacttatat actttatgtg
     2521 taaattatgg taaaaatatt atttaatcaa atcaaaactt gatttatata cctggaaaag
     2581 gtattatatt aaagagtgct taaaatacgc atttcataaa tagctatata taaaataata
     2641 aataaggaga gtgatgggca atggatacta gtccgttgcg gagagaattt tttacatttt
     2701 catcacttaa taatatctaa aatcaaaact aatacatata ttcagttata taaattagtt
     2761 aattaataga tactattaaa tgatgagatt tatataaaac tgaataaagg atgtgttgcc
     2821 atgataagat attacaaaac tatagattca aaattagaga aacttagttt ttttgaagat
     2881 ggctgttgga taaatcttgt tgaacctaat catagtgaaa tcaacgaaat ttctaattta
     2941 ttaaatatag atgtagaaag catagaatct gcactagatg aagaagaacg ctcaagaata
     3001 gatgttgaag acaatcatac tcttatactt atagatatac cagtagacga aagtgactct
     3061 aattcttctc attatactac aataccctta ggtattatac taactgaaga agctattgta
     3121 acagtttgtg atgcacaaac taagatttta aatgacttta tagttggtca tattaaagat
     3181 ttttttacgt ttaaaaagac tcgctttttg cttcaaattc ttcacaaaaa tgcagcttat
     3241 tacttgcatt acttaagaaa aataaataaa atgacaatca taatagagcg agaaatttac
     3301 aaatcaatga aaaacaaaga attggttcaa ttattggaat tagaaaaatc tttggtatac
     3361 ttctctacct cactaaaatc taatgaactt gttttaaaca aaatggttag aactgctggt
     3421 ataaagaagt atccagatga tgaagaccta ttagaagatg ttatagttga aaatagacag
     3481 gctcttgata tggctaaaat atatggagat atattgagta gaattatgga tgctttcagt
     3541 gcaattataa gtaataatca gaataatgtt atgcaaattt taacagtagt tacactaatt
     3601 ttctcaatac ctacaataat atcaggattc tttggtatga atgtcatcaa catgccattt
     3661 tctaataacc caaacggatt ttggataata cttcttatta cctctataat atgtatagtg
     3721 attacatttt tcatgtcaag aaataagcta ttataaaata ttaataaaaa agccattaga
     3781 attaattgat ttacatttat cctaatggct tttatatatt taaatctata taatcttata
     3841 atacttttta actatcatgt tcttcatcta taatcatttc agtttcaagc ccttctagca
     3901 ttgaatctaa actttctttt atatttagta tataaattgg tacatactct tcttcatcta
     3961 ttacctcttc ttgcaactta aatggaggaa ttaatacttc atcaaagtct atatttaaat
     4021 taggaaagcc ttctactatc tcttcacaat tatcgtactc ttcatttgct aaagaaacgt
     4081 acatatctag gctcttttta taataaagac ctgcaagcat atactcacac ttcttacttc
     4141 catatttaat accttcttta taatatttct cagcttctgc gtcatcattt aattttaaat
     4201 aaatttgacc taaattatat attgattcaa cacaaccttg tgctctagcc ttttcatacc
     4261 aaaatttaga atttacataa tctttataga acatatcata aattaatcct accatatgtt
     4321 gagcatacac attattttca ttggcaggtg tatcaaacat cattttagac tcttccaatt
     4381 taccttctct aaaataaatt ctacctagat gtatacgagc attcatatgg tttttgctac
     4441 ttgccatttc aaaatacttt ctagcatttt ttgtatttcc taagctctca tatatacacc
     4501 ccaatctata actagacctc gtatctccat tttcagatgc tttcttatac caacttattg
     4561 cttcttcaat attatttaaa tcttcataga tatttcctaa tttgatttga caagatacat
     4621 tatttggaat cctcgaataa tacgaaatcg ctttttctat atcttgattc tgataatata
     4681 aatcccctag attttcaagg gaacttttgc atccaacagc tatagcatcc tcataatatt
     4741 taatagcatt ttcataatct ttttcttcaa aatatatacc tgccagatta ttttttgctt
     4801 ctgttatatc atcttcagca gccattttat aataagtttt tgccttctct atctcatttt
     4861 ctctattata taaattagca agtctatact tagaaagtgt atgatttttt tctattgctt
     4921 tctcataata ataaattgca tctcccagct cttcttttct atcatataca tatgcaagcc
     4981 tatactcaga cttcacatca tctctatcag cactcttttt ataatacttc tctgcatctt
     5041 ctaaattatc atttatttcc ataatcatac ccaagttaaa gcaacctttc atatgacctg
     5101 acttgtacaa ctgtttatat aaacttactg ttgatttatt atctttcttt tttccattta
     5161 atattgctaa attatatttt gcatcatcat ctaaaagcac agaacctttt ttatagtatt
     5221 catatgcttc atcatctttc tccaaaaaag tatataatac ccctaaatta aaacaagctt
     5281 tacctaaatt cttgtctgct gctgttttta accatttttc acaccttaca aaatctttca
     5341 ttttaaaatg gcatacacct aaattatttt gtgcttgtaa ataacctaaa tttgctatct
     5401 tttcatacca atatatagca tattcatagc catctaactt atagtacata ttacctaaat
     5461 caaaagcagc atcttcactt ccacttttat atgccattga ataccacttt tctgcttctt
     5521 taaattgttt tttactttca tatatatttc ctaaagtata ttgagatttt acgtaattat
     5581 ccaatgcagc actcttatac aactctattg cgctttccat cttacccatc ttttcaagga
     5641 gggcaccctt agtatgtacg actttcgggt cattagatat attttttatt ttttttatag
     5701 aaaattttgt atttttcatt attcgctacc tacccatttt ataaaatata ttctctcaaa
     5761 cattattata cattataatc tacaattaat gctataatat tgaattttta ccttttgtca
     5821 ctatattgta acattaaatt ttaaatttta taatcattag attttattat gtaattggta
     5881 tataatgtat atataggggg gacattttat gaatttcagc aatattttta tccaagttgc
     5941 agttttattt ataattattt tagttggata ttttgtcaga aaattcaact tattagatga
     6001 ccactgcaca tctaagcttt caactttgac aatgacagtt tttttaccat caatgataat
     6061 tagctccatg caaattaact ttgatagtaa aatgatacaa aaaatactat tgttattatt
     6121 tacatctttg attatgtata tagtttcaat tataattgca tttttattga aatacatttt
     6181 aaaatgtaat gataaaaaag atttgggaat ataccagtat atagttgttt tttcaaatgt
     6241 tgcttttatg ggttatcctg taattgaagc agttttaggt catgaagcaa tattctatac
     6301 tgcaatattc aatttgcctt ttaacttatt ttctttcact ttaggaattt atcttttatc
     6361 taaaggcagt acaagtagag gtttttcaat aaaatcactt ataagccctg ctacaatagc
     6421 tattgttatt ggactttttt tatttgtaac aggacttagg ttaccccaat ttataaacga
     6481 gccacttgag atgttgggaa gtataactac accaatatcc atgattatca ttggaagctt
     6541 acttgctaat tcttcagctc tcgattgttt tgtcaacaaa aaattatata tagtcacttt
     6601 tataagatta ttggtacttc ctgtgattgt gtattttatt ctaaaaggat ggataaatga
     6661 taagatgatt ttagctatac cagtagtaat ttcttcaatg cctgctgctg caaatactgc
     6721 tataatggct aatcaatatg actccaatat aacactagct tcacaatgtg tgttttttac
     6781 aacactattt tcagttatat ctataccttt tataagtatt ttactcttat cttgatttat
     6841 ttttttatgt attatataat aacatattca ataaattaca aatataaaca ttttattgta
     6901 gtatattgat ggaatttttt cctagatatt tgtcaataat atctatatgt attatagaat
     6961 aggaggctta aatatggata tggatttact ctttaaaata gtatttgcta tagttgctat
     7021 aggtgtttct gtaaaaatca ttaaaactgt tgctagttta gcttttaaaa tagcgttgat
     7081 attgctaata attttatttg tatatagaat gtttttgtaa acatttaaaa ataagttttt
     7141 taacacaata gagaagtaaa atagattatc tttaatgtaa attttttatt aaagacactc
     7201 tattttactt ctctattagc ttatttaaat taaattttta ttatatcttc ccataatata
     7261 aacatcttca aattttccat ctctgattac agcatatttt ttagttccct ctatttcaaa
     7321 acctagcttt ttatataaat ttaatccctt ttcattatcc acaattactt ctaatcctac
     7381 tctagttaac ataatccaat tatctgctat atctaaaagt tgttccataa gcttcttacc
     7441 tactcctctt ccctgataat tctctgcaac acttattcct atttctgcgc tatgtctcaa
     7501 tcgtggagaa gaatttacat gtaacccagc aaaacctatt acatcttttt ctccattatt
     7561 attagtttca gctacaaaca tataatcatt ttctcccaaa gaagctaaca tagcttcagt
     7621 tttatcgact ctgtcactca ttaatgccaa agtatttctc ataacactgt atgttcttct
     7681 aatttcatta aaagcttgtg catcttctct tcttataggt cttattgtta tatctatagg
     7741 cttactcata ttggattccc cctcaaacat aatctttatt tttaattaaa attttacatc
     7801 tttattttat actgttcaaa tctatgtatg cttctacctg aggtacatat atcatattat
     7861 cttttatatg tgtacttcca aattctttta attctgtacc ttctttatcc ttagttattt
     7921 tatatctaat ggattccata ccttcaacta cttcagcatg aaaaaacata ccttcatatt
     7981 gtttaaatct aaaattaaaa ttgtctttag taagttttat tatcatattt tcatctactc
     8041 cttatataat tgatattttt cttattatta gttgtatata tactgcttat tcatattaat
     8101 atattataac ttatcattta tttagtataa agttataaat agatatattt atacttattt
     8161 tacaatcttt cttcaattga tatataatat gtttatataa actaatgtat gtgaggtgaa
     8221 atatgagcaa aaaaacaaaa tatttttctt taattctctt tcctattgct ttgcttttaa
     8281 attttatagc cagtaaagtt ccaaatattg ttgaaaaata ttactcccaa ttcatagata
     8341 aaataattgt acaaatattg agtaaagttt ctggaatttt cccattttct ctctatgaga
     8401 ttacaatgta cataatagtt atatctatct tcttattttt atgttgtact ttatctacaa
     8461 tttttaataa gaaaaaaaaa ttaaacatat atttaaaaaa ttccatttta aatatattat
     8521 ccattgtatc aatagtctac tttctttttg tagtgctttg gggaataaac tataatagga
     8581 ttccactaga aaccacactt ataaataact ataatttaaa aaacaatacc tctatccaat
     8641 caaaacaata tagtgttaaa gagcttacta aattatataa attccttgta attaaagcaa
     8701 atgaaactag aaaactcaca ttacaagata aaaatggtat tgtaaaatct aatacagatt
     8761 ataatggtgt cataaataga gctcaactag gatacgataa tatcttggat atattaccta
     8821 gtgttagtgg tagttattct aagcctaagt atattatttc atcaaatcta atgtgctata
     8881 caggaataac tggtatatac tttcctttta caggtgaggc aaatgtaaat atagcaatac
     8941 ctgacttata tattccttgt acagttgaac atgaaatggc acatcaaagg ggatttgcta
     9001 gtgaagatga ggctaatttt atagcgtatc ttacttctat aaaacacccc aatattgatt
     9061 ttaactattc tggatatatt ttagctttaa attatactgc ttctgcttta agtaaggttg
     9121 attataatgc atatgttgat atttctgctg gcatttcaga ttctgtccgt agagatttaa
     9181 aaaatgaaag tgaattttgg caaaaatatg aaggtaaaat taatgaaatt tctaatgagt
     9241 ttaacaattc ttacttaaaa gctaatggcg ttactgaagg tactcagagt tatggtaaaa
     9301 tggttgattt attgctaact tattatgaat tatatccata taactaaaca ctacaattca
     9361 aaattttatt catatacagc tgatattaaa tcagctgttt tctatttaaa taaattattt
     9421 aacttcaagc aatcttatat aatttgatag tacttatact atctgtataa catatcaatt
     9481 ctaactattt tagttaaaac atttctatta tcttttttaa taaatgtttt aactaaaatt
     9541 tttaaaacat aaaacttcca cattatttca ctatctatat aaaaatctaa aatttcacat
     9601 ataaaattac ataactaaaa aatcataaat ttatagaaaa catatattca aaataaaaaa
     9661 gcatgtatca aaacttgaca catgcttata atcttatgta tatatatcat tttgtcacaa
     9721 taaaaatttc cttgtaacac tgatattttt aaacaaaata gtccttattt aattaaatta
     9781 acattaatta aattcgtact cattttgcta tcattaaaca ttacttatag taattttcta
     9841 atacactatt tgaaacttcc ttcccttgaa aacttttcaa ccaattctca tatgctgagt
     9901 ttttccatac actaccatca ttaaatgtta cttgttttac acaagatata atgtacttta
     9961 caccatgctc tccagttgat tgtttccatt tatcaaacaa tagaaaggca tcattttgat
    10021 tcttacctgg tgctattgca ttttgctttg catattcttt ctccatttgt ttccattctt
    10081 tcaaccaatt ttctacccat gccttgcctt gttgtttttc aaacatactt attatatcct
    10141 gtggtggtga ttgttgcatt tttctataag tatgtgaata tgattttgga gacacaggag
    10201 atatgcctgt aacaatacca tagtctacac cagctgggct aaatccaaca cttcctactt
    10261 cgccatctgc tgccacattt tgagcatccc aatatagctc aagtggtttt ccatttttat
    10321 catatgctaa gcatgtaatt tcataatcca taattgcctt ttcactgcta tttgttaagc
    10381 ttataacatt gctaggccaa tgatatggag tatcatcata ctgtattttg ctattattta
    10441 taaataatgg aatattatca ttataaacaa gacctttact actttgaata tctgatacct
    10501 tctttgtgac agtacttacc gtatttgcta agtatacatt tgttttttct gaattggtcg
    10561 tactaagaga aaatgttgtt gtcgttccag taatcagcaa agcaacaact aaaataggta
    10621 agctagatat ttttttatat ctcacagttc ttcacctctt tttctattaa cttataataa
    10681 aacaatttac caaaacatta aaatctatgt taacataatt taccaactgt tctagtaact
    10741 atatcctatc atagttacta tcaagtttca atactattga tggaaatttt cactatatta
    10801 aatctttttt taattttata aatttacaat atgatttaac tcatacatat atagtcaaat
    10861 tagaatataa gtttcttaca tttaatgaag tttataaaat aaaaaatgac tagataatta
    10921 aatactgtaa ataaaaactt attacaaaag tatttaaaaa tctagtcaat taatatatat
    10981 atgaattgta tactataatt tttcaatctc ttctagcaac tcatcaacta atttgttacc
    11041 atcaatcatt ctaactattt cacccttttt aaataaaaga ccttcacctt tacccccagc
    11101 aatacctata tctgcctctc tggcttcacc aggtccattt acagcacagc ccataattgc
    11161 aacagtgata tttttttcca tactaccaat cttttcttca acctcattta caacactaat
    11221 taagtctata ttacatctac cacatgtagg gcatgatata actttaatct tatcatttaa
    11281 aagtcccaaa cttcttaaaa tctgtttacc aacaataacc tcttcaacag ggtcgcctgt
    11341 taaagatatt ctaacagtat ctccaattcc tttaagaaga agtgctccta cccctataga
    11401 agactttatt gttcctttgt gaacacttcc agattctgta attccaatat gaagaggata
    11461 atcaactttt tttgatatta attcatatgc atcaacagtt ttataaatat cggatgattt
    11521 tagagatata actatattat gaaaatctaa gtcttcaaga atcttaatat gtcccattgc
    11581 actttcaact aatgcttcag cagttgcaga gccatacttt tttaaaagtt ctttctctaa
    11641 agaacctcca ttaactccaa ttctaatttt taaatttctt tccttgcatt tctcaactac
    11701 catcttaact ctctctatac ttccaatatt accaggattt attcttattc catccacacc
    11761 ttgttctata gcttcaaggg ctagcttata atcgaaatgt atatctgcaa taattggtat
    11821 atttacacta gactttatct ttgctatatt tttagcagct ttaatatcag gaacagcaac
    11881 tctaactata tcacaaccag cttcctctaa tctctttatt tgagctattg tagcatctgc
    11941 atctcttgta tcagtatttg tcatagattg tatacttata ggattttctc ctcctatttt
    12001 tacagttcct acacttactt ctctcgtctt tcttctctcg taactcatat tccacctcta
    12061 tatattattt tatattgaat ctctttaaat attaaaatat tataacctac atgtatatta
    12121 taaattaaaa agctatctag ttaaataaga ataaatttca tatataaaaa ttaatttatt
    12181 cttatttaaa actacatagc ctattttctt aaaatctcta aaaaactaaa tcattgaaat
    12241 aatcttagta tatctttata tgtgataaaa agcataaata acattaaagc tccaaaacca
    12301 acaacattta tcatgccttc tttatttggg tcgagttttt taccacctct aacagcttct
    12361 agtaacaaca taagtattct ccatccatca agtgctggta ttggtaatag atttactata
    12421 cctaaattta agcttatgac agctgctaaa tacactacat ttatgatgcc tgtacgagca
    12481 gcatctgata ccataccaat aacacctact ggtcctgcta cagcattgcc aatccctcct
    12541 ggtacacgtc ctgtaatcat ttgacctaga aatgttagca tctgttttgt catatctaca
    12601 gtagttttac atgcatttac tattgaccct aaaaagtctt tttctctttg tggttgaatc
    12661 cctatttcat actttccatt gttattttta ggtgttacat ttacaacttt atcacttcca
    12721 tctctagtta tactaagttt taattctcca ccagaagaag cgtttattat atttgcaact
    12781 tcatcccaag tcttaacaga attaccatta attttattta tcttatctcc tacttgaagc
    12841 cctacagcct gtgcaggagt atctggcatt atctttccta atttagtcgt tggagaacct
    12901 atatacaaaa atactggaac taaaagtatt gctgctaata ttatattgaa tattggtcct
    12961 gctacaatag tactaaatct ttgtaatata gacttgtttc caaaagaatt tggacttatt
    13021 tgttcttcat cttcaccttc catgctgaca tatccaccaa ttggaagtgc tcttatagaa
    13081 tactctgtat ctttttttac gctatatatc ttaggcccca tacctataga aaactcattt
    13141 actttgatac cacttctttt tgcaaatata aaatgtccta actcatgtat taatacaatt
    13201 atactaaata gtattaatgc ggctattata gtcataaatt caccttccta tttttttatc
    13261 agatttgcaa cataagctct actccatcta tctgtttcta agatttcttc taatgttggt
    13321 tcacttatgc tactatgaac ttctaaagtc ttctctatgt aatatggtat gtcatagaaa
    13381 ccaattttat cctctaaaaa ttcacttact aaaacttcat ttgctgaatt taaaacagaa
    13441 gaataagttc ctcccatttt taaacactca tatgccaatt ttaaacatgg aaaagtttct
    13501 aaatctggtt cttcaaaagt taaagtacta aattttgaaa aattcattct ttcaaagcta
    13561 ctttccattc tatctggata tgtaagagca tactgtattg gtagtctcat atctggacat
    13621 cctaattgag caattattga gctatctgta tactgcacca ttgaatgaat tatgctttgt
    13681 gggtgaacta ctacatctat attttcttgt tctactccaa ataaccatct agcttctatc
    13741 acttcaagtc ctttattcat aagcgttgaa gaatcaatac ttatttttct tcccatactc
    13801 caatttggat gcttcaaagc ttcattttta gttatatttg caagttctcc ctttttcttt
    13861 cctctaaatg gaccaccaga tgctgtaagt attatctttt ctatattttt tttattttct
    13921 ccatttagac attgaaatat agcactatgt tcactatcaa caggaagaat atttacattg
    13981 tatttttctg cttctttcat tacaagttca ccagcagtta ccaacgtttc tttattcgct
    14041 aatgctatgt ctattccctt ctttatagca caaagagttg ggactaatcc tatcatacct
    14101 actacagcag ttaaaaggac atccacttca tcaagtgatg atattatttt taatccttcc
    14161 attcctgcta aaacttctat ttctatattt ttaggcaaca tttcttttaa tttcaatgct
    14221 ttattttcct caaaaactgt tacatattta ggtttaaact ctactatctg ttctagcaat
    14281 aattcaatat tactgttagc tgatattgca actatctcaa acttatctct attatctcta
    14341 actacatcca aagtttgttt acctatagag cctgtagaac ctaaaattga tatctttttc
    14401 atataataat cctttctaat aataaatata ccctgtcaaa acattataac actactaaaa
    14461 caattatttt tactattcat agaaatttca tatattattc cacagattaa aattaatcta
    14521 ttattttttg tattttgtgg aatattataa aatattctag tattattaaa tgcccttttt
    14581 tatttccaca acatcttcta ttttacagtc tagtgctaaa catatcttct ccattgtatc
    14641 catagaaaca gatttatcat ttcctagtct gcctaaaaca gaaatactta tacctgatat
    14701 atttacaaat tccattttct ttattttttt gtcaattaac aatttccata atggagcgta
    14761 tgaaatcatg ttatcacctc gcaaaatata ttctatcaca ttttatctat tttggaaaat
    14821 tttcatct
//
LOCUS       DAGQVA010000096        14481 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.096, whole genome shotgun sequence.
ACCESSION   DAGQVA010000096 DAGQVA010000000
VERSION     DAGQVA010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.096"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(113..766)
                     /locus_tag="MIV85_003277"
     CDS             complement(113..766)
                     /locus_tag="MIV85_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2962597.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPIAEMKKEKLL"
     gene            complement(1011..2876)
                     /locus_tag="MIV85_003278"
     CDS             complement(1011..2876)
                     /locus_tag="MIV85_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBY2962598.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2881..5301)
                     /locus_tag="MIV85_003279"
     CDS             complement(2881..5301)
                     /locus_tag="MIV85_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBY2962599.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     TEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5315..6757)
                     /gene="glgA"
                     /locus_tag="MIV85_003280"
     CDS             complement(5315..6757)
                     /gene="glgA"
                     /locus_tag="MIV85_003280"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBY2962600.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6786..7916)
                     /gene="glgD"
                     /locus_tag="MIV85_003281"
     CDS             complement(6786..7916)
                     /gene="glgD"
                     /locus_tag="MIV85_003281"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBY2962601.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7918..9078)
                     /locus_tag="MIV85_003282"
     CDS             complement(7918..9078)
                     /locus_tag="MIV85_003282"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBY2962602.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            complement(9849..10892)
                     /locus_tag="MIV85_003283"
     CDS             complement(9849..10892)
                     /locus_tag="MIV85_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBY2962603.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(10913..11359)
                     /locus_tag="MIV85_003284"
     CDS             complement(10913..11359)
                     /locus_tag="MIV85_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBY2962604.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(11537..13117)
                     /locus_tag="MIV85_003285"
     CDS             complement(11537..13117)
                     /locus_tag="MIV85_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBY2962605.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            13916..>14481
                     /locus_tag="MIV85_003286"
     CDS             13916..>14481
                     /locus_tag="MIV85_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962606.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSL"
BASE COUNT         4609 a         2570 c         1431 g         5871 t
ORIGIN      
        1 ctatcgtagt gccttagagt ttttatttgt atttaaagtt aaatttattc ttgtttttcc
       61 tttaatattt aatagtaaaa caacaaaatt ataaaaaaaa taaagagaaa ctttataaaa
      121 gcttctcttt tttcatctct gctataggta tcgttttcca atgttctctc aaaattcttt
      181 caacattttc taaatcattc tccctcatag attttactac ttcaatatgt tgattattgc
      241 tgtatgtcaa cattttatat aactcatctt cattatcact agtatatgac tttgacataa
      301 aattatatct taaagagttc aatagattta ctaacacctg attatctgat ttagttatgt
      361 atatatcgtg aaattcatta cttaatttta aatagctatt gtaattttta tactttatag
      421 agaccgccat catttctgtt aattcttcca tttttactag gtctgattca gttaaatttt
      481 gtaatgctga agaaccggct aacgcatcca atactccaat tacggaatag gtgtctaatt
      541 tctccttttc ctgaaattct tttactacaa atcccttatt aggtattttt tctagtaaat
      601 tttcacctgc taacctagtt aatgcttctc tcgctggtgt tctactaact ccgatagatt
      661 tacaaatctc agattcagta attctctgat tagcttcata ttctccattt tggattttct
      721 ttgatatata gtcatatact tgagttgtaa gtggatctac cttcataaga cgttcctcca
      781 tattaagatt ataaaagtta aatctcccta caactttggt agagagttca gttttatctt
      841 actaatttat ataatatcac aattatgata ttttttatac ttctttgtaa tattttgaaa
      901 tactaaaatt cttatgataa tttatacaaa aaaagtagaa aaagttttga taaaacaaaa
      961 ctctttccac attcgcctta ttttctattt atttttctaa aaaaagatat ttaatttact
     1021 ctaaaaattc taaatgattt agagtctaaa tctactttca actcattatt ttcaatttgt
     1081 atagtactat ttgcattttt aagactatac tttataggta tttcctcaat aaaactactc
     1141 tctatacata atgatatact ttccacattt tcacttctat ttactaaaat taacattcta
     1201 tcattatttt cattaactct aataaaagaa aatacagaat cattattagt atatataaat
     1261 tctgtatttc cagaacttaa aagtttattc ttatttctaa tttttataac atctctataa
     1321 aaattaagca tatcttcgtc ttcatttttc catggataag ttcttctatt atctggatca
     1381 acacctccac aaagacctgc ttcatctcca taatatatat atggtactcc ttcaaatgtc
     1441 atctgtatag ctacagcaag cttcactaaa tctacatcat catttaattc cgttttagct
     1501 cttgtaacat catgtgttcc aattaaattt aaattagacc taaatgattc ttttggataa
     1561 ttttctttaa tctgcatata tctattacaa agttcatatg aattaatttc tccttttaag
     1621 aaagaaaaca tgttatttct aaaaggataa cccataacag aatctaattc ttcacctaat
     1681 aaataacttc ttctctgacc atagctaatc ttatttgatg catcttccca tacttcacct
     1741 ataagaattg agtcatcatc tgcctttttt aattcctttt ttaactctct tataaactta
     1801 gttggtaatt cgtctgcaac atctagtctc cagcccttaa tacccatatt tacccattta
     1861 tttataacgc tatcattgtc atatattata taatccatat agctatgttc taattcattt
     1921 atatttggca atgtcttaac atcccaccaa cttttatatt tttgaggaaa ttcttcaaac
     1981 atataccatg aataatatgg agattcttta gattgatatg ctcctaaact attatagttt
     2041 ccatacatat taaaatattt actatctgct ccagtatgac taaaaactcc atctaatact
     2101 attgatatac ctttttcttt tgctttatca ataagttctt taaatgtatc ttcatctcca
     2161 aacattgggt caattttttt atagtcacct gtatcatact tatgattact agaggcttca
     2221 aatatagggc ttagatatag tatacttaca cctaattttt ttaaatatcc aagtttattg
     2281 attatccctc ttaaatttcc accatggaaa tcccatctta taacatcccc ttgactatcc
     2341 tttatgtaca taggtgtatc ttcccaattt ccatatatga aactattttt tttaggatta
     2401 tcaaccttac cactacgatt tccattattg aatctatcta caaatatatg ataaagtatt
     2461 ccttctttgt accatgttgg tactttaaaa tctttataaa cagtgatttg atatttatta
     2521 atatcactat aattatattc acaagaatat ccattatctc tgttttttcc ataaaataaa
     2581 gtctttattt gaccatccat ttcaacatca actttaaagt aataaaaata aacacctgta
     2641 ccatcaaact tttcaatctt accacaaaag cactttccaa gtttatcatt atctaattct
     2701 tcatttaaag ttattgttct catttcttct tctctattta tttctaggga aatagacttg
     2761 atattgtatc cctcatttac tttaacacaa atggtcaatt cctcatcaaa ttttaaagct
     2821 ccaaacggag ccttaaaatt tttatcccaa gagttatatt ctattacact ttgcatttaa
     2881 tcacaccctt ttaaaccaaa tgtcttttgc atactcagaa attgttctat cagaagaaaa
     2941 aaatccagag ttagctatat taactaaaga cattttattc catttttctt tatctctata
     3001 taacctgttt atatctgctt gagcttgacc ataattttca aaatctctca atacaaaata
     3061 ctcatcattg taagtagtga gtgaattata aatacttctt ccttcttcgc caagattagg
     3121 aataaatcca tttattaaat catctactac cctttttata tccatattag aatgatatag
     3181 gtcaagtgaa gaatatccac catatttatt ataatttagt acttgttctg cactaagtcc
     3241 aaataaaaac atattttctt taccaacctg ttcacatatc tctacatttg caccgtcaag
     3301 tgtagccaaa gttatagcac cattcatcat aaacttcata ttacttgttc cagatgcttc
     3361 cttagttgta gttgaaattt gctcactaac atttgctgct ggtattatta tttctgctaa
     3421 tgatactcca taattctcta aaaatactac ttttaacttg tcctttactc taacatcatt
     3481 atttatagta cttgcaacag aatttataaa tttaattata catttagcca aataatatcc
     3541 tggtgctgct tttgcgccaa atataaaagt tcttgggtca agattcaaat taggattatc
     3601 aagtaattca tgatacatat gaagtacatt aaatatattc agtaactgtc ttttatacgc
     3661 atgcaatctc ttaacttgaa catcaaatat cgaacttggg tctacattta aatcgtattt
     3721 atcttttata aactttgcta gatttgcttt attattgtat tttatatcat caagtctttg
     3781 taaaacagag gaatcatttt taaatttttc aatatttttt aattgtaatg tatctttctt
     3841 ccatgaatca ccaattaaat ctgtaattaa attgctaagt tgaggatttg aacttataag
     3901 ccatcgccta tgtgcaattc cattagtctt attattaaat ttatttggtt catcttgata
     3961 gaaatctttt aatacctctg tttcaagaat atgagtatga agcttagcaa ctccatttac
     4021 actatgactt gtgacaatac ataagtttgc catattgata ttgtcacagt ctattatact
     4081 cattcttttt attctatctt ggtcatatcc tttattattt aattcctcta catatcttct
     4141 atttatttct tctattatca tataaattct tggtaatagc tctttcatca tacttacagg
     4201 ccatttttcc attgcttctg acattatagt atgattagta taggacactg tttttttagt
     4261 tatttcccat gcttcatccc aagataaatt ttcttcatca agcaaaattc tcataagttc
     4321 tggtatgcat aaggtaggat gtgtatcatt tatatgaatt gctaccttat cgaataaatt
     4381 attaatattt aatttgttct ttttatattt tcttattata tcttgtatcc ctgcacttac
     4441 aaaaaagtat tcttgtttca acctcaacaa cttacctgca tagtttgaat catcaggata
     4501 taatacctgt gatatttcct cagtataata cttatgtttt aaagcctctt catagctacc
     4561 agaataattt agagcatttg aggtaagttc accaaaatct ctctttggta tttcactctt
     4621 aaacaatctt aaagtattta tacattggtt ttggtatccg attattggta tatcataagg
     4681 cattgccatt acaggaaggt agtttttatg aattactttt aaatgactac cttccttgat
     4741 taattctacc tcaccaccaa acttcaccat tgttgcttca tttggtctta cagtttccca
     4801 tgcatatcgt ccttctgtaa gccagttatc aggcacttct acctgataac catttacaaa
     4861 tttttgttca aacagaccat atttatacct tattccatat ccttgaccac ttatgttcaa
     4921 agatgccata gaatctaaaa agcaagctgc taatctacca agtccaccat ttcctaaggc
     4981 tgggtctact tcagtttcaa ttaaatcatc caagttgatt cctaattcag ataaaccttc
     5041 tctaacttct tcttcaatat ttaaatttaa taaattagat tttaactgtc tccctattaa
     5101 aaattctaaa ctaaaataat aaacttcttt tttcttatct aactttgtag caacccattt
     5161 ttttgctatc tcatctttca atagactaca taatacattt aacaattgtt catcagtagc
     5221 ttccttgata gattgtgcat ataagctata catttttact tcaaattttt gcttgaattt
     5281 ctttttgctt attgttacca aaaaaaccac tcctttaatc acatatgtct ctatatgttt
     5341 ctatatactc cttagctgat tttttccaac tattatctgt tttcattgca ttttcaacta
     5401 atttaatcca tttttctttg tccttaaata ctttgattgc atttttcaaa cagaaaaaca
     5461 tctcatgagc attgtaattt ttaaaactaa atccattgcc ttctccagta aatttattat
     5521 aaggtgttac tgtatctcta agccctccag tctctctaac tattggtaaa gaaccatatc
     5581 tcatagctaa catttgacct ataccacaag gctcaaataa tgatggcatt aagaacatat
     5641 cacttgcagc atatatctgt tgagccaatg atgcattaaa agtaattcta gctgatactt
     5701 tatctgaaaa attagaatcg taatagttga acattgattg atattgatgt tctccagttc
     5761 ctaaaacgac aatctgtaaa tcttctctca taagttctgg catcatgtat gctattaaat
     5821 caaatccttt ttgagaaact aatctcgaaa ctatacctat caacggaata gatgaatctt
     5881 ttttaagtcc caatatatct tgtaatctca atttattttc tacttttttg tcaattgagt
     5941 ctacatcata atgaacaaat atatctttat cttttgcagg gtcatttaaa tcataatcta
     6001 taccatttaa tatacctttt aattttcctg actcttttct aagtaatcca tctaattgtt
     6061 caccataaaa agatgtttgt atttcatttg cataagtagg actaacagtt ataattttat
     6121 ctgcaaaatt tataccagct ttcataaaat ttattgagcc ataatactct atatctccat
     6181 tatcaaagta tttttgtggt aagtccaata tatcatataa aacatgctta tcaaatacac
     6241 cttgatattg gagattatgt atagtataca tagtttttat atttttatac ccctcaaggg
     6301 ttgcatatct ttcttttaga attaatggta acatccctgt atgccaatca tttatatgta
     6361 ttacatctgg ataaaaatca attctactta tagcttctaa aactgcatct gtaaagaaag
     6421 tatatctttc tgcatcatct ccatatccat agatactctt tctttcatct tctcttctaa
     6481 aataaaattc attatctata aagtaaaatt ttacaccatc taattccatt tctaaaagac
     6541 cacagtattg atttctccat ccaacacgta cactaaacac agctatttct tttagttgat
     6601 cttttaaata acttggtata gttgaatatt tgggcattat tacccttaca tctacacctt
     6661 ctttttttaa ttctttaggc aatgcataag aaacatctcc taatcctcca gtttttgcaa
     6721 agggccaaca ctctgctgtt acataaaaaa ccttcattag tcattccccc ttctaaaaaa
     6781 tttatttata tatttgtatt cttttccact acaagaggat atttttcatc tcctcttaat
     6841 tctttcccat ttgatacact cgtattttta tctaatattg cattatatag ttttgcattt
     6901 gactttatta cacaattttg cattactatt gagttctcta taactgttcc tttttcaaca
     6961 tttacctttc taaatatgat actatctttt acagtacctt ctattaaaca accagatgct
     7021 ataaagctat tttctacttt agcactatct gtataaattg taggtgattc attcttttct
     7081 tttgtaaata tctttctttc agaatataat aattcatctg caacttctaa atttaataaa
     7141 tctttgctca tttcaaaata tgattcaaca gaatttacac attttagata tcctgtatat
     7201 tcataggctc ctattttcat attttctgct tcttcaataa taaattcttc taaataacaa
     7261 taattgcctt tatttacaat gttatatata cattcaacaa aatcttcacg cttcataata
     7321 tatgtctcca tacatatgtt tgctctaggg aacttaccta aattatttcc tacatttatt
     7381 accctattgt tactatctaa atttagagtt aagttaccag caaaatcttt atttgcatta
     7441 tttacatttt tatatattat agttatatca ttatgagatt ttttatggta ttccaatgct
     7501 tgagaataat ttaaattgca tagcatatag cttggagcta ttaaaatata ttcttcttca
     7561 ctcttttcta tataatctag attagctaag atagtatata tatcaccttc tctatgtgag
     7621 taagtatttc tatacttagt gttttctgga ctaaaaattg ataggccacc tttttttcta
     7681 cttaaatccc aatctttacc actacctata tggtctgtta atgatctgta tttttctttt
     7741 gcgaatattc caactttagt gattcctgaa tttatcatat tagataaagc aaagtctatt
     7801 attctatatc ttccagctat tggtgtagat gctattggtc ttccatagtt aagtttgttt
     7861 attgctgggt ctcctttttt gtttaaattt attatcccta aacattcatt tctcatctta
     7921 aagacctcct tctattaata cgcatctagg ttcgatattt tcatactcag aaactacatt
     7981 tatttcatta tttacattct ttatctgaac attatcattt atagttgcac actcacctat
     8041 catagctttt tctatagtta cattttcacc tattacaaca tttggcatta ttactgaatc
     8101 aattacttta cttcctttac caacaacaac tccatgtgat aatacagagt tacctacttc
     8161 acctaaaatt ctacaaccat cagctatcat tgatctatga acatttgcat ttttacctat
     8221 atattgtgga ggcattgcca tagtatttgt atatatcttc cacttagggt ctgctaaatc
     8281 aagtgtttct ggagatttta ttatatccat attagcatcc catagacttt gtatagttcc
     8341 tacatctctc cagtatcctt taaatggata agcatacatt ccaacattat cttctaacat
     8401 tttaggtatt aaattttttc caaaatcatc ataatttatt tctggatttt tttctgcttc
     8461 cttaaaataa tttctcaaca ttttccaatc aaatatgtat actcccatag atgccaaatt
     8521 gctcttaggt tcacttggtt tttcttcaaa ttcatagata cttgaatctt catttgtatt
     8581 cattatccca aatcttgaag cttcatccca aggaacttca atcactgcta ttgtagcttt
     8641 agagcctttt tccttatgaa attttaacat tttgctataa tccatcttgt atatatggtc
     8701 accagataat atcaatacat attctggatt ataggtatct acaaagtcca tattttgata
     8761 tatcgcatgt gctgtaccat tataccaatt tccttctttt tcattcataa atggttgtaa
     8821 aacatagaca ccaccattta ttctgtccaa atcccaatga cttcccatgc ctatatgtga
     8881 atttaatatc aacggtctat attgagttaa aacacctaca gtatcaatac cagagtttga
     8941 acaattgctt aacacaaaat ctataattct atacttacct ccaaatgata cagctggttt
     9001 ggcaattctt tttgtaaaaa cacctaatct tgaaccttgc cctcctgcca aaatcatagc
     9061 taacatctct tttttcattt aatgacactc ccctcatcta gtaattaata tttataattg
     9121 catttttact tttataaact ttatcagtca ataaatgtcg tgtataaatg ttgcttaaat
     9181 aataccttaa taaaaataaa ataatatcaa ctatacaatt gatataatgt ataccccata
     9241 atggacttac cgacgtatac attattttcc ataagcacta tagtatttat taatattcaa
     9301 ttattggtta aaaaataata caaattttat tttataaata taaaaacatt ttttataaat
     9361 cctttgtgtc atatgaacat gcttattttt taatttgtta aattcgtaat agcaaaatat
     9421 aatctaatat ttgttaaata attatccaaa gaaaatcaag taattattaa tcaactttat
     9481 tttttaattg atacttcttt gtctataatt taaacaaaag gatataaact tttaaattat
     9541 ttattagttt tcttagtatt aatgtttata tttttataaa tatatattaa taatataaat
     9601 agactaacta aaaccatgct tatttgctat atgttttata ttatattata taacactttt
     9661 tacattagta aaggataaat tgtataaaga ttctgttaat ttatttttat aatttcatct
     9721 ttctaataaa aacaaagaag aagacttaaa aatttataag tcctcttctt ttcaacgtgc
     9781 atttttgtgc tatatttaat taattcgacc tttaatttcc atatccttcc tatgataaca
     9841 aaactctttt atttttttaa tgattcatta tcatttaaaa cttcttttat atcaagtact
     9901 tctttgttat catcactcat aacttccttt attcctttga atgttcctag gaaattaact
     9961 gcttctgaag gtaaaaccag ttttgttgac ttaccttcag ccattttttc aagagcttcc
    10021 atagatttta atgctagaat attattgtct atatcagcct ctttcattgc tgaaaaaact
    10081 aattttaaac cttctgctgt tgccatttga gttcttttta tcatttcagc ttcaccttgt
    10141 gccttagcaa tagctgtctg tcttatagct tcagcttcac cttctgccac taatatagca
    10201 gattcttttt caccttctgc tacacgtacc atagcttctt ttttggcttc tgctgttaat
    10261 attgcagatt gtttttcacc ttctgcttga agtattgcag ctgacttatt accttctgct
    10321 tgaagtattg cctctcttct ttctctttct gctctcattt gtttttccat tgcaacttga
    10381 atatcctgag gaggcattat attttttaac tctactctat ttacttttat accccattta
    10441 tctgttgctt catcaaggat agttctcatt tttacattta ttatatctct tgatgttaat
    10501 gtttcatcta aatcaagttc accaattata tttcttagtg ttgtagctgt taaattttca
    10561 atagcagcta ttggattagc tatctcaaac acatatctaa ctgggtctgt aactttataa
    10621 tatacaactg tatcaatctg catagttaca ttatctttag ttataactgg ttgaggtgga
    10681 aaatctatta caatttctct aaggtcaatt acatatgcca ttttatctaa aaatggtatt
    10741 aagaaatgta cacctgtttc agctactttt tgaaacttac caagtctcat tattatacct
    10801 actttagatt gttttataac tcttatacaa gttaaactta ttgctacgac tactactatt
    10861 aatacaatac ttaaaacaat tttagtaccc atactataaa tcctccttta ttctattggt
    10921 ttgtcacatt aactgtggcg tctacttttt taacaactaa ttttacccct tcaattttta
    10981 atacttctac tgtagaacct ttttctatct tttcaccatc tatagaaata gccgtccatg
    11041 tttcatgttc aactacaact agacctgtgt tatttggaga aatctcttct gtaacaatac
    11101 cttttttaga catcattgct tgtaaattag tgttagattt atagccttta tcttttttta
    11161 ctattttttt agtagctacg actaacattg ctatagaaat tactgcaaat attaaaattt
    11221 gtaagaaaat actctctata aagctactta aaaatataag tattacagct cctacactaa
    11281 accatatcaa tgttaagctt ggtgttaaca tttctgctat tccaaataag actgctacta
    11341 tcaaccatat taacttcata ctatctaccc tcttttcata tgaattataa aaccctatat
    11401 aaattatatg tttatacaat gtttttgaat ataaatttaa attacaaaac aataaaataa
    11461 attaattaat taattaatag tattatatca acatactttg ttaaatttgt tacaaagtag
    11521 tatcaaatat caccaattat atatccaaca actctttcat tgttaatgaa atgttactta
    11581 ttaaatccgt agcatttacc gtatacattg ctttgctcag tttatctcct atatagccat
    11641 gtatatatgc tccactaact gtagcttcca atatatccat accttgacct ataaatgaag
    11701 taatcattcc aagcaaacaa tcacccattc caccagttgc catacagcta tttcctgtag
    11761 gatttatata tgttttttta ccatctgtta tgacagtttg ataacctttt aaaagcacca
    11821 ccagattata tttttgagca aattcttttg caacatctac tctatgttct cttatatacc
    11881 caattgaatc tcctgtcaac ctggccattt ctcccaaatg aggtgtaatt acaaatctat
    11941 ttttccattc taaaaactta taacatctgt ccttcataac gttcaatcca tctgcatcta
    12001 atactattgg gcaattagaa ttttctacta tcttaagtaa tttatcaaat gtttgactat
    12061 tatctcccat acctggacca aaaccaattg catcactaga attaagtaat ttatttaatc
    12121 tttcttcttc aaaatttaaa gtcattgctt ctgtaagtct aatagatacc ttttcttgca
    12181 catcttcact actaattaat gttacaagtc cactcccact cttaacagca gattcagttg
    12241 ctatgaaact tgcaccataa aatccttttg aacctgcaac tatagatact tttccaaaat
    12301 cacttttaaa accatgctta tctcttcttc taatattatt ttttacaaaa gtcttatcag
    12361 ttatgaactc ttcatcatgg tattttcttg taataaaatc tggaacacct atcttttcta
    12421 caactacatc acctataagt gcgctagtgt catagtttag aaaacctctt ttataaaact
    12481 caaagctaat cgttttgttt gctctaatac aagttcctaa tacatttcca ttatcgctat
    12541 ctatacctga aggaatatct atagaatacg tatttttgct attatcgttt actatgtcaa
    12601 taacttcttt aaaaatacca gttatatcac gttttaatcc agtcccaaat atagcatcta
    12661 ctacaacatc acttttagat actctatctt taaaaattgt taaattttta ttttttataa
    12721 tattttgttt ctcaacttta ataattttat ctacttcatt ttcctctcca taattttttt
    12781 cacttaaatc atttttatta atatttataa tattaattcc catatttaaa agtacattgt
    12841 aatttatttt agagcattca cttagttttt caagattacc tactaaaaat acgtttactt
    12901 cttttccata tgtatttaga tgtcttgcta ttccaagacc atctcctcca ttatttccaa
    12961 caccacatac aactgtataa ctattataca tgtctatatc catatttttc attgcagata
    13021 taaccgcatt ttccatcaat acaatcattg gaatccctac ttcttctaca catgcagtat
    13081 caacatttct gcttaattta gatgtaccta ttagcataaa ttatcactcc tataaagtta
    13141 aagacttctt aaatacttac caaaaatatc tattgaaatc tttttaatcc cataaatatc
    13201 ataaataaaa tcactaaaac taagagtttt gaaataattt aaaataacaa aaaattttga
    13261 attaaaacaa ttatttaatt tattatacca tataatttaa gttattatgt tgatttaaaa
    13321 cctatttaca ctaattatct aaatatctct ttatttttat aatcttttat gacttattta
    13381 tatttttcat ttttataaaa aaacaataat taagaatata actatattct acatgtaaaa
    13441 atttttttat ttaaactcaa ttttctgata atttgataat ttttcaaaat ttatagttga
    13501 cttttatttt ttactgtatt aaactaatta ctatacaaaa cagaaaacaa aattttcaaa
    13561 attattaaat taaaaggaga ggtaaatatg aagactttat taaacaaaca agtacgattt
    13621 tttagtagcc aatttagtta gggtttgtac ctaagttaag acaaattgtc ataacataga
    13681 tacaagcccc ttaggattat gatttttaag gattgtatct atgttggcta tagtaattgt
    13741 tgttaaagtt tttattttat catcataata tagagccaca tggattatac tgtgtggctt
    13801 attcgaattt ttgccataca gttatatata ctgtgtggtt tttttatatc aaaatcattt
    13861 tttaaaacca aattttaaaa accatttaaa atattttcaa aggggtgttt tatttatgtc
    13921 aggtattata tctgtaatga cgcaaagttt aattttatcg attatggcac tgggggttta
    13981 tataacttac aaaatcttag attttccaga tatgtctgct gatggtagct atacaatggg
    14041 tgcttctatt gtagcatttt ctcttactaa tggtatttct cctgtagtag caactttaat
    14101 ggctatctta tgtggttgta ctgctggtct tgttacaggg attcttcaca ttaagtttaa
    14161 gatatctaat ttactttctg gtattttagt tatgggaatg ctatactcta tcaatttaag
    14221 aataatggga aaatcaaata ttcctctatt tagctttaaa cacttattca atggggaaat
    14281 atctcctata gttttagcct tagcttttgt attcatctgt aaagtccttt tagatttatt
    14341 cctaaaaaca ggtcttggat acactttaaa aggtgttggt gataactctc aaatgattaa
    14401 atctctaggt ataaatatag gttctataaa aatactagga cttatgattt caaatggact
    14461 tatagcttta tctggtagtc t
//
LOCUS       DAGQVA010000097        14062 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.097, whole genome shotgun sequence.
ACCESSION   DAGQVA010000097 DAGQVA010000000
VERSION     DAGQVA010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14062
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.097"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..1396
                     /locus_tag="MIV85_003287"
     CDS             <1..1396
                     /locus_tag="MIV85_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBY2962607.1"
                     /translation="TSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKG
                     NTVFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDM
                     VFAKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPN
                     AGGKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSH
                     IKNIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEI
                     KKFATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEY
                     VIDRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDK
                     FNNVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKK
                     ALKKIQKEIRENRK"
     gene            complement(1459..2082)
                     /gene="ytaF"
                     /locus_tag="MIV85_003288"
     CDS             complement(1459..2082)
                     /gene="ytaF"
                     /locus_tag="MIV85_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBY2962608.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            2270..2914
                     /locus_tag="MIV85_003289"
     CDS             2270..2914
                     /locus_tag="MIV85_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962609.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            3128..4186
                     /locus_tag="MIV85_003290"
     CDS             3128..4186
                     /locus_tag="MIV85_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBY2962610.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIAHYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            4290..5474
                     /locus_tag="MIV85_003291"
     CDS             4290..5474
                     /locus_tag="MIV85_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBY2962611.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHVCKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGTKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            5681..6394
                     /gene="rpsB"
                     /locus_tag="MIV85_003292"
     CDS             5681..6394
                     /gene="rpsB"
                     /locus_tag="MIV85_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBY2962612.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            6473..7384
                     /locus_tag="MIV85_003293"
     CDS             6473..7384
                     /locus_tag="MIV85_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBY2962613.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            7469..8173
                     /locus_tag="MIV85_003294"
     CDS             7469..8173
                     /locus_tag="MIV85_003294"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBY2962614.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            8199..8756
                     /gene="frr"
                     /locus_tag="MIV85_003295"
     CDS             8199..8756
                     /gene="frr"
                     /locus_tag="MIV85_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBY2962615.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            8759..8962
                     /locus_tag="MIV85_003296"
     CDS             8759..8962
                     /locus_tag="MIV85_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962616.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            8991..9725
                     /locus_tag="MIV85_003297"
     CDS             8991..9725
                     /locus_tag="MIV85_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBY2962617.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            9738..10517
                     /locus_tag="MIV85_003298"
     CDS             9738..10517
                     /locus_tag="MIV85_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBY2962618.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
     gene            11341..13152
                     /locus_tag="MIV85_003299"
     CDS             11341..13152
                     /locus_tag="MIV85_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBY2962619.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSMMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(13240..13821)
                     /locus_tag="MIV85_003300"
     CDS             complement(13240..13821)
                     /locus_tag="MIV85_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962620.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         5744 a         1431 c         2340 g         4547 t
ORIGIN      
        1 aacatcaact gtaaataaaa agtatataca agagtttata ataagtaaaa gaaatgatag
       61 atatgtaata ccaattaaat cttcttataa aaatgaagtt aatggtacta tattagatac
      121 atcatcaaaa ggaaatacgg tatttattga acctattagt gtttcaaatt taagtacaga
      181 gttaactatg ttaaaagctg atgaaactat tgaagaatac aaaatattat cttatttaac
      241 agaacttata tttgagaaga taagtcagat aaaattaaat atagagatac tttcagaata
      301 cgatatggta tttgcaaaag ctaagtatag tcaaaaaata aaaggaatta ctccaaaaat
      361 aaataataat ggctatataa aaataattaa aggtaaacat ccacttctaa caggagatgc
      421 agtaccttta gattttgaaa taggcaaaaa ttatagaagt cttataataa caggtcctaa
      481 tgcaggagga aaaactgtaa cccttaagac tgttggttta ctaactttaa tggttcaatg
      541 tggatttgat atttctgcaa aagaaggtag tgaatttagt gtatttgaaa aagtttttgt
      601 agatataggg gataatcaaa gtattgaaaa tgccttaagt actttttcat cacatataaa
      661 aaatattgca gagattatga gtttatcaaa taattctact cttgttctgt ttgatgaaat
      721 aggaagtgga actgaaccta atgaaggagc tggtttagca atatcattat tagaagagtt
      781 ttacaaaatg ggatgtataa ctatagcatc aactcattat ggagagataa aaaagtttgc
      841 tacattgcat ccagaatttg aaaatgctgg tatgatgttt gataaagaaa cgttagaacc
      901 attgtataag ttaactattg gaaaatctga agatagtaat gctcttttta tttctaaaaa
      961 aatgggaata aaaaatagag ttttagatag agctaaagaa tatgtaattg atagaaacta
     1021 caatttagat ttagttaaaa gaagtaagct acaatctaat attgaagata aaaatagttc
     1081 tgaagtcatt ttaaactata cagattataa tgtaggggat aaggtaaaat tactagatga
     1141 agatgatttt ggaattgtat ataagcctat ggacaagttt aataatgtag aagtattgtt
     1201 taatgataat tttatttcag taaatataaa aagattacaa cttagcataa aagcatcaga
     1261 attgtatcca gaagggtatg atttagatgt attatttact agttttaaag aaagaaaatt
     1321 agaaaaagat attcaaagag gttcaaaaaa agctcttaaa aagattcaga aagaaattag
     1381 agagaataga aaataaatat aaaaagcaca aaagaaagca atctaaagag aaaagtttat
     1441 ctttagattg ctttcttatt aacatatctt cataaatcca atgactaaca agattaaacc
     1501 acttaaccaa gataagttta aatttacgtt tttaacaaac atatttccta gtaaacaacc
     1561 aagtaatact gcaattatat ttgatattaa agaaaataga ataacttgta tataattcac
     1621 acctacaagg ccactaccaa aaccgatagc taatccatct aaacttaaag caagtgcaag
     1681 tgtaaatgct tcagcagatt taagcacttt agatttactt gtatctaaga catcaggttc
     1741 aatacttaca ttaaaattta atttaaggtc taacatatta aaattataat tctttgagtg
     1801 tatagatttt ttcttaaaat aagatttaaa aaaactttca attagtctag cacttcctaa
     1861 taaaaataaa ataaagaaac atattaacat tgttatattt tgaggtaaaa agtctctaac
     1921 tattgtacct gcaaaaagcg atattgctaa aatagctgaa caaactacgc tgataattat
     1981 atttgaatat aagggaactt taactttatt tacgccatat ccaaagcttg tcacaaaggc
     2041 atctatacaa agagaagtaa ctaataaaat tgattcaatc acagtagatt aacatccttt
     2101 ctcttaaatt ttgtacttat attagttata gtattgtaaa aatggataaa ttgttacaga
     2161 taatccaata aattgttgat aaaattccaa catcatacaa cacctaaata acaaaagaat
     2221 catatcatat aataatataa aaccaatcat aataaagcag gtgaaaataa tggaacaaca
     2281 tagtaaggtt gggaatttcg gtgatttgtt gaaagtttta ttagatgaaa aagaattatc
     2341 aatgggagaa ctaagtaaaa aaagtggaat tgataaatct actatatctc gtatagctaa
     2401 taataaacaa aagccaaata taaatcattt agaaaagatg gcaatacatt taaatattaa
     2461 cctagaagaa ctgttgaaag cttcaggata tgaatttaga aacagcaata atcaaatatt
     2521 taatgcagat agtgatttta gtaactttga tgatattctt ggatttgcaa atttaatcaa
     2581 tgataagaac tttaatggaa atattgaaaa agagttaagt aagtgtaagt tatatgtcca
     2641 aacagatgaa ggtaaaaaat tactttttga taattttaat aaaaaaatag attctattga
     2701 aaaacaaggt caatttacag atagattaag acaaatgtat gctgattttt gtacagatgg
     2761 acttacaata aagaaatatt tattgattgg aagtatgcta ctttactttg ttatatcaac
     2821 agatgtgatt ccagacttcg tgttcccaat aggatttatg gatgatttag tagcattaaa
     2881 tatagttaca aaattactta aaaatgataa gtaagtttta gaatcatatt taatatataa
     2941 ataaatcaaa gtatataaaa tttattattt tttatatgaa acaaattaaa agcacaatga
     3001 agtagattaa aaatttaaaa ctaagaatct aatatatatt ttgtaactat ttaagtatat
     3061 aaaataaaat aatatccaaa ctaatacaaa atagtaataa ttgttttgta ctggaggata
     3121 tatatttatg aattgtaaat ggatatctaa aatagatgag agaaaaaaat gtcatagaga
     3181 agcagattct tctggatatt gtatctttca taaagaaaat aagtctgatg aagagataca
     3241 attgatgatg gatactcttc ataaagaaga gataagtgaa tttaatggat ttgtttttga
     3301 aaatgaattt aatgcggaag aaatattaac ttacaattat aaaatactgg atttttctga
     3361 atccatattt aaacaaaaag caaattttaa aaaatatatt tttaaaaaga atattatttt
     3421 taactataca gaatttagag ataaagtttt atttaatggt tgtgtattct tagaaaactg
     3481 tgattttaat agaaccatat ttagtaaaca ctatataaat gaccgtatat ttgaaaaagt
     3541 gaaatttaaa ggacctgatt tggtagttaa taaagtagaa aattttccac gaatggatgg
     3601 aataattttt agcatgtgta caaaatttgt gttaaagaat gttgaatatg gaaaaagtga
     3661 gtatgagcat ggcaagataa attatagaat agctagaaat caagcaacaa aaattggaga
     3721 atatgagatg ataggatttt actattataa ggaaagaatt tatagtagta aaataatgaa
     3781 acgttctaat tatcctacct tcagtgatta tttagttgaa aaattttttg accaaatagc
     3841 acattacaca acaggttatg gagaaaagcc atggaatata ttattagtta ttatagcaat
     3901 aataagtgtt tttgctttat tatacttatt tgtaggcata gaaagttcaa atagcacact
     3961 tgtagcttta gatataaata atataggtga ttactcacta agtgagattt tcaaaatgta
     4021 tatggattta tggtatttta gcatggctac atttagtaca gtaggatatg gagatatggt
     4081 tgctacaagt ttgattggga aagcattggc aggtatagaa gtattttttg gagttacaat
     4141 aggagcaatt tgggcatctg tgattattaa aagaatgata aggtaatatt tgtgtaaata
     4201 tggataggta ttaattacta gatataaatt ggactaaata gggaaaattt aaatataaat
     4261 atacttaata atccaagaag gtgaaaaatt tgaaaaatgc actaaaaaaa attatatcat
     4321 tagccatgat tctagttttt ataataccaa attattcata tgcagatgat aaatctgtag
     4381 acaagtattc aaaaacatct atacttatag accaagaaac aggtagagtt ttatatagta
     4441 aagaacctga tatgaaggta ccattagcta gtttaagtaa gatgatgact tttttacttg
     4501 caatagaagc tattgaaaat aaagaagtaa aagaaactga taaggtaaaa atagacaaat
     4561 ctattgcatc agtaaaaggg tcaagttata aacttaaaga tggtgaagaa gtgccactta
     4621 tagagcttat gagaggtctt atgattgtat caggaaatga tgcggcaatt gctatagcaa
     4681 aacatgtttg taaaacgaaa gaagcatttg tagatagaat gaataaaaaa gcaaaagaaa
     4741 taggaatgag taatacacat tttctaaatc caaatggtct tccaatatac gatttaagca
     4801 accccaaaaa accagcaaaa gaaaatatct ctactgcaaa agatatagct attcttggaa
     4861 aatacatgtt tgaccattat gaaaaacaag taacagctat aactgatatg gagacatata
     4921 caaattcaga tagaagtttt gaaaaaagca atacaaatgc attattaaga attataccag
     4981 aagtagatgg tataaaaact ggatatactg gcaatgctgg atattgctta tcattttcta
     5041 tggttgtaaa taaaaatgat aaaaatgaga aaaaacgtag agtaataggg gttgtattag
     5101 gtactaacca taaaaataaa agaacctctg cttcattagc tctactgaaa tatggaaaag
     5161 aaaatttcaa tatgaaaaaa gtaattgata aagatagctt tattggtaag aaatatataa
     5221 aaggaacgaa agagttagag gttacattaa aagcaaaaga tgaactttat acaatattaa
     5281 aagatgatga aagtataaag tcagaagtta agattaaaaa tatagagtac cctgttaaaa
     5341 aaggtgatac tatgggtatt ataaaatatt atactaattc aggtgactta cttggaagtg
     5401 tagatatagt aagtaataat agtatagata acgtatcatt aaaaacaaaa ttaaaaatga
     5461 aatttgcaaa ttaaattcaa aaaatggtat aaaatacaca aaaaaatata aaaatagaaa
     5521 atatggaaaa aatattgtta tttcttcacc tctgtgatat actactagag gtgaaaaaat
     5581 aaaataaatc acacacagca ttgggatcct taaaaggtgc ctattacatg gttttttagg
     5641 gagaagatca agctggaggt ataaaaccag gaggtaagat atgtcagtaa tatcaatgaa
     5701 acaattatta gaagcaggtg ttcactttgg tcaccaaaca agaagatgga accctaaaat
     5761 ggctaagtat atattcacag agagaaatgg aatatatata atcgacttac aaaaaacagt
     5821 taaaaaagtt gaagaagctt acaagttcac taaagaagta gctgaaacag gaaagccaat
     5881 cttattcgta ggaactaaaa aacaagctca agatgcgata aaagatgaag ctgaaagatg
     5941 tggaatgtac tttgttaatg aaagatggtt aggtggaatg ttaacaaacc acaaaactat
     6001 aaaaacaaga ataaataaat taagagaatt agaaaaaatg gaagaagaag gcgtatttaa
     6061 tgttcttcct aaaaaagaag ttataaaatt aagagctgaa aaagaaaaac tagaaaaata
     6121 cttaggtgga ataaaagaca tgcctgaatt accaggtgca atgttcgtag ttgacccaag
     6181 aaaagaaaac atagctattc aagaagctca tagattaggt ataccagtag ttggtatagt
     6241 tgatactaac tgtgacccag aacaattaga ctttgctata ccaggaaatg atgacgctat
     6301 aagagccgta aaattaataa ctggtgctat ggcaacagct gtaattgaag gtagacaagg
     6361 tgctgaggaa gaagtagctg aagaccaaga ataataattt gacaattaaa tggtaagggt
     6421 cgcccttacc atttataata tggaatagaa taagtaggag gaaacttaaa aaatggctaa
     6481 tataactgct caaatggtaa aagagttaag agaaagtaca ggcgcaggaa tgatggactg
     6541 caagaaagct ttacaagaag ctgaaggaaa catggaaaaa gcagtagatt tattaagaga
     6601 aaaaggatta tcaaaagctg ctaaaaaagc tggtagagtt gctgctgaag gtctagttgc
     6661 aatagaaatg aatgatgata atacagttgc ttctatggta gaagttaact cagagacaga
     6721 tttcgttgct aaaaacgaag acttcaaagt gttcgttaaa gatgctgctt gtatggcatt
     6781 agctactgat aaagaagata tagcttcttt attaggtgaa actcataaag agggaataac
     6841 tttacaagaa gttttaaata atagagttgc aaaaataggt gagaaattag actttagaag
     6901 atttgctaaa gttgtaacta atggacaagt tgctggatac attcacggtg gtggaaaaat
     6961 aggtgttctt gttgaaatgg aaacagaagc tagagatgct aaagttttag aattaggtaa
     7021 agatgtagct atgcaagttg ctgctatgaa tcctaagtat gtttcaagag atgaagtaga
     7081 tgctgaatac atagcacatg aaacagaagt attaactcaa caagctttaa atgaaggaaa
     7141 accagctaat atagttgaaa aaatggttaa aggaagatta gaaaaagaat taaaagaggt
     7201 ttgtttatta gagcaaactt tcgttaaaaa tccagatata actgttaaac aattagttgc
     7261 tgatgttgct aaggcagtag gttctgatat aaaagttgtt aaagttgtga gattcgaagt
     7321 tggtgaaggt atacaaaaga gagaagaaaa ctttgcagaa gaagttgcta agcaacttaa
     7381 gtaataacca aagagagaac acgcaggtgt tctctttttt aaaaaataga aaaaattgga
     7441 tatgaaggat tgaaatagga ggtttctgat ggataaacca atgtacaaaa gggtattgtt
     7501 aaaattaagt ggagaagcat tagcaggaga aagaggtttt ggtataaata atgatgtagt
     7561 taatgatatt gctattgcta taaaaaaaat acaagaaata ggtgttgaag tagctgtagt
     7621 agtaggtgga ggaaacttct ggagaggcag aaccagtgaa ggaatggaca gaactactgc
     7681 tgactatata ggaatgttag ctacagttat gaatgcaatg gcgctacagg atgcactaga
     7741 aaatatagat gttgctacaa gagttcaaac tgctatagac atgagacaaa ttgcagaacc
     7801 atatataaga agaagagcag ttagacactt agaaaaggaa agagttgtta tatttggtgc
     7861 aggaacagga aacccttact ttacaacaga tacaactgct gctttacgtg ctgctgagat
     7921 ggaagcagaa gttatattgt tagctaaaaa tgttgatgca gtatatgaca aggatccaaa
     7981 agtacatgca gatgctaaga aatttacaga attaagttac atggaagtta tacagaaaga
     8041 attaaaagta atggattcta cagctacatc tttatgtatg gataataaaa ttccaataaa
     8101 ggtatttgag cttacaacag agaatataat aagagcagta aaaggcgaaa atataggaac
     8161 tactgtaaaa taatgaagaa tgaaggagga gtaaaattat gaaactggaa atacataagc
     8221 aattagaaga gaaaatgaat gggacaattg atgctttaaa gtttgaattt ggaactataa
     8281 gagcaggaag agctaatgca caaatgctag acaaaataag agttgattat tatggaactc
     8341 caactccaat aaatcaaata ggtgctatat ctgtaccaga accaagaata ttaatgatat
     8401 ctccttggga taaatctgct atgcatgaaa tagaaaaagc gatagctaac tcagacttag
     8461 gattaaatcc atcaaatgat ggtgaggtta taagactttc tgtacctgct ttaacagaag
     8521 aaagaagaaa agaattagct aaaaaagcta gtaaagctgc agaagaattt aaagttagaa
     8581 taagaaatga aagaagagac gccaatgaga aaattaaaaa gatggaaaaa ggcggagaat
     8641 taactgaaga tgaattaaaa aaagcacaag atgaagttca aaaaatgact gataaattta
     8701 taaaagaaat agatacatta ttatctaaaa aagaaaagga cataatggag gtataatatt
     8761 gaaaaaatat tataaccttt taggtcttca tgtagatgag gtaaaacaat attttgatga
     8821 gcaaaatata aattataccg taaaatctat tgaaggtaaa aaggataaag aaaaacttgt
     8881 agttcctaga gttataaaaa tatctgagat aggtgatagt gtagaactga taatcacata
     8941 cttttctgac tccttagttt aaggagtcag aacaatattg gaggcaaaat atgaataaca
     9001 acattatata tgatatagac ttaaataaca tacctactca tattgctatt ataatggatg
     9061 gaaatggaag atgggcaaaa gctagatttc ttccaagaac tgcaggacat aaggctggag
     9121 tagaaactat aagagatata gtaaaagaat gctcaaaatt aggtgttaag cacttaacat
     9181 tatatgcatt ttcaacagaa aactggaaaa gaccgaaact tgaagttgac acacttatga
     9241 acttattatc tacatactta agaaatgaaa tagctgaact tcaccaaaac aatgtaaaag
     9301 taactgctat aggagatata agtgctttac caaaaacttg tataagagaa ttaaactcag
     9361 ctaaggaact gacaaaaaac aatacaggag ttaacttaaa tttagcatta aactacggaa
     9421 gtagagcaga tataaaaaat gctcttatag atatagtaaa aaattgtgaa agtggtaaaa
     9481 tagatataaa caatattgat gaagatatta taaaaaacta tttaagcaca aagtctatac
     9541 cagatccaga cttggtaata agaacaagtg gtgaacaaag attgagtaac tttttacttt
     9601 gggaagttgc ttattctgag ttttacttta ctgatataca ttggcctgat tttaaaaaag
     9661 aagaactaca gaaggctata tacgtatatc aaagaaggga tagaagattt ggaggactta
     9721 agtaaggaga ttattttatg cttacaagaa ttattgcttc actagctctg gttccattat
     9781 ttctatttgt tgtatatgga ggtattcctc tatatatagc tgagacagca atagtttata
     9841 ttgcattgca tgagttttat aaggcattta aaataaaaga tgtacatcca atattcatta
     9901 taggatattt attttctatt tatttagctg taaaaaatat ttttaattta ccattagaat
     9961 atacttatgc agtaattttt attttatttt tagcaagtat aatttatatg ttgatgggca
    10021 aaaacaatgt tatagatgtt tcgattacgt ttttaggagt tttttatata ggagtatttt
    10081 tagattttat aattataact ataaatggat ttgaaaaagg tagtatatat gtatggctta
    10141 tatttgtgat atcttttatg acagatatat ttgcatattt tagtggttat ttacttggaa
    10201 aacataagct aattcctaaa gttagtccta aaaagactat agaaggagct attggaggaa
    10261 taataggaag tacactttgt tgtattttat ttggatattt atttggcatt gatttgcttc
    10321 aattagcgat aataggaagt ataggaagtg taatagctca attaggagat ttatttgcat
    10381 cttctataaa gagatatgta gggataaagg attatggaaa gataatacct ggtcatgggg
    10441 gtatattaga tagatttgat agtgttatat tagttgcacc ttttgtatat agtgcgatta
    10501 aattttttat tagataaaga ttggttggat ttaaaagagc aatctataat tgctagtaat
    10561 gaaaatagct atgtaacttt taaatgcaga gatattctgc agttattagt tacatggcta
    10621 ttttcattgt tcaaaaattt agaagacctt ggggaattgt ataagaatag gtattacttt
    10681 ataatagtat actatatttg tagtgagtat attttttata ctataactat cattaaaaaa
    10741 tatttttttg tttaataatt tcgatatttt tagctttatt atatatttat aatatatatg
    10801 tataaatgta actaatttat tatccattta taaattttat ttttaaatat aattaataag
    10861 aaataagtaa attattggtc ttattacaca aaaatagata taatttaagt aatataccaa
    10921 aaaaaaggaa tatatttaca taatatgata aaataaattc aaagagttaa attgtaggta
    10981 aatagtattt taattattta ttaaaatata gattatgtat atgccaaatt taaaaagaga
    11041 cataaagaca ttatacaaat atattattgg ggtgatattt tgtaagaaaa gaagtgatgc
    11101 agtaaattaa ttgagtaatt taaaaatgat ttaatgataa tgttgatgaa tgtttaaaaa
    11161 gaaattttag aaaaacgtat attgctgttt gtgttggagg tgatgaattt gtagaattta
    11221 tagggtataa atgattaaac tatttaagat aaatacatat cactgtaaaa tattgataat
    11281 cattttttat aagagattga ttatttgcaa attatatata ttacaaatga ggtaacaata
    11341 atgaagaaaa aatatgattt tttaatttat tctgctattt ggctagttat tattattctt
    11401 tttatatttt ctctatatca cagtatagag catattaaaa ttataagtca cactggtact
    11461 attcgcagtg aaactcaaaa ggttgttaag caagaattga ataatgaaag aaatgatgac
    11521 ttaataaaac gactggataa tattctgata aagctaagaa caggtaatgg agaaaatgga
    11581 tttcaaagat gtgataataa agaatttcaa caaaaactaa atcaaatgga ttctatgtgg
    11641 gaatctatga agaaagaaat tataaaagtt agaaatggtg cttcaggtga taaattatat
    11701 aaattgagtg aagagtattc tgtgttgtct aatcaaattg tttttatatc tgaaaaacac
    11761 tctaatgcaa aattgtattc ttttgctact gcactattta tttatcttat attctcaaca
    11821 ataagtcttt taatttggga atattataat aaaaaaaggt ttaaaagaat attttatact
    11881 gataatttaa caaaaataaa aaatcaggtt gcatttgaaa acagagcgat tgaaattttg
    11941 cacaatgcat ctaacaaaga gtatgtactg ctaaatattg atattgacaa ttttaaatat
    12001 attaatgata cacatggata tgaatatgga gataaagttc taataatagt tgcagctgca
    12061 ctttctaaaa cttttaatat caaagaaact tgtgcaagaa ttggttcaga taactttgta
    12121 atacttgcaa aatatagaga ttctctttta gaggatattc gggaaatgct aactaatgct
    12181 ataatctctg aattagatat gaatgtaact caaactatat cttattgtat aggagcgtac
    12241 ttagttgaaa ttgataattt aggttataaa tccatcaatt ctatgatgga taaggcaaat
    12301 attgcacaca aggtaagtaa aacaagagga atttcctcta cagtatggta taatgagaat
    12361 ctgttaaaac agttacaaat ggaaaatagt atttataatt atatgtataa agcgatagaa
    12421 aatgaagaat ttcatatgta tttgcaacct aaatttcaaa tatcttcttt aaatgttgtg
    12481 agcgcagaag ctcttgtaag atggttttct ccagaacttg gttttttatc accagatgaa
    12541 tttattccat tgtttgaaaa aagtggattt attattgaat tggactttta tatgttaaaa
    12601 aaagcgtgtt catttgtaaa aaaaacgttt atgaaaaaaa atcaatatac atatccgatt
    12661 gcagttaatt tttcaagggt tactatttac caaaatagct tttatcaaag gtttttagat
    12721 actgttaaag aatatgaaat tccttttaag tatatagaga tagaggtaac tgaaagtgct
    12781 tttaatgaaa tatctcaacc agttatttcg attttagagg agcttaaaaa gttaggattt
    12841 ttaatttcga tggatgattt tggatcagga tactcttcat taagtctttt atgttctcta
    12901 tctattaatg gattgaagtt agataaaagc ttacttaaag aaacatttaa ccgggagaaa
    12961 gtatatagta ttattcagtg tattattgaa atgtcacatc gtataggcat gtctgttgta
    13021 tgtgaaggta ttgaaactaa aaaagacttg gaatttttaa atacagttaa atgtgatgta
    13081 ggacaagggt tttatttttc taaaccgata gaagaaaaag aattttttaa caaatatgta
    13141 actaaaaaat aatataatta tttttatcag tctatacatt gagtcatttt atatctcgtt
    13201 aaatgactca atgtactgtt atgtatttta aaatataaat tatttaaaac gttttttata
    13261 cttatataga aattcttcta tattttttga ttgttctctt atttcaactg cttctatatc
    13321 tagtaaataa agtatagaat catttgtaag ttcaacatat tcaccatctt ctgaaccgag
    13381 tgcatgtctc tcaattttta atcctttttc ttcataatat ttttttgttt ctatatataa
    13441 tgattctcgc ttttgtatgt agtctttcac ttcattattt ggaaagttat atgaatccac
    13501 taatgtttcg ccatttataa aagttttctc ggtagcaact ttttcatccc aacaatggat
    13561 ttcttcccaa gtaaaaaata tctcagttcc atctggaatg aatgaaaacc tggtaataat
    13621 atataaataa ttattgaaat ttacttcata atattcagga atatcttcaa attccatata
    13681 gtaatttgta taattaaaat tactattatc tttttttaca aagggtattt tttcaataaa
    13741 tttatatatt gattgttcat ttttaaaaat tcctatatca taactttttt caaattgatt
    13801 aatttttaat aaatacaaca ttctttctcc ttttattcaa aatataattt ttataaattt
    13861 actaatcttt agctttttta attatatatt tacatatgtt tatatgatac tataataatg
    13921 tgttttaaat agatatataa tagtaaatat tttttatata gttatgtttt agtaaaataa
    13981 tgagataaat atatataaag tttaattttt gaacttatgc ttttgtttta ttttaacata
    14041 tttatattta ataaactata at
//
LOCUS       DAGQVA010000098        13722 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.098, whole genome shotgun sequence.
ACCESSION   DAGQVA010000098 DAGQVA010000000
VERSION     DAGQVA010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13722
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.098"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            68..208
                     /locus_tag="MIV85_003301"
     CDS             68..208
                     /locus_tag="MIV85_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962621.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(383..703)
                     /locus_tag="MIV85_003302"
     CDS             complement(383..703)
                     /locus_tag="MIV85_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBY2962622.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(823..1560)
                     /locus_tag="MIV85_003303"
     CDS             complement(823..1560)
                     /locus_tag="MIV85_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBY2962623.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1775..3598
                     /gene="acd"
                     /locus_tag="MIV85_003304"
     CDS             1775..3598
                     /gene="acd"
                     /locus_tag="MIV85_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBY2962624.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3813..8111
                     /locus_tag="MIV85_003305"
     CDS             3813..8111
                     /locus_tag="MIV85_003305"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBY2962625.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8315..8776
                     /locus_tag="MIV85_003306"
     CDS             8315..8776
                     /locus_tag="MIV85_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBY2962626.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8806..9960
                     /gene="nusA"
                     /locus_tag="MIV85_003307"
     CDS             8806..9960
                     /gene="nusA"
                     /locus_tag="MIV85_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBY2962627.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            9967..10248
                     /locus_tag="MIV85_003308"
     CDS             9967..10248
                     /locus_tag="MIV85_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBY2962628.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10238..10549
                     /locus_tag="MIV85_003309"
     CDS             10238..10549
                     /locus_tag="MIV85_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBY2962629.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10571..12511
                     /gene="infB"
                     /locus_tag="MIV85_003310"
     CDS             10571..12511
                     /gene="infB"
                     /locus_tag="MIV85_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBY2962630.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12554..12934
                     /gene="rbfA"
                     /locus_tag="MIV85_003311"
     CDS             12554..12934
                     /gene="rbfA"
                     /locus_tag="MIV85_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBY2962631.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            12915..13592
                     /locus_tag="MIV85_003312"
                     /pseudo
     CDS             12915..13592
                     /locus_tag="MIV85_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT         5474 a         1572 c         2581 g         4095 t
ORIGIN      
        1 ataataacag atattataat taattaacag tttttgtaag tatttgacaa tagagagggt
       61 gtaacaaatg ggaataatag agtcagcatc aaaattggct gagatggttc atttattggc
      121 tgttgaaaag gggataactg atatagaagc atgggatgaa gctgtgaaag aatacagcaa
      181 aatttatgaa gaaagaagaa atgaatagaa tgataaaaaa tgaaaacttg atgataaaaa
      241 ataactttat ttaaagaaat tcaattttta tagaagtatt aaaaataata taaataaaaa
      301 gatggtattt caaatgtaag taaaaaatca ttttgggata ccatccttat tatttatttt
      361 aataatatat aagtaataaa tcttacttat ccatattttt tatgtaacct cttttttcta
      421 acttttttat atgctcctta cgtatttcat caagattaat accatattgt tcttctagct
      481 taaacatcat agtaacacat gtctgcgcta catccattag ttccttagca gttttcttta
      541 taatatcaac ttcatctaaa tcattatttt ctccacttag atttctgaat ttacctatac
      601 attcagctaa ttcaccttgt tcttcaccca ttttgataaa tgtagattct agtgttgggt
      661 ctaaattatt aagctctggt aaagatatag tttttagttt cataaaagct cctttcaagt
      721 tattcgtatt tatactaaaa catcataaca aaaataatac taaaaaaaaa ctttaaattc
      781 aacataaaaa cttacatata taataaaaat catgaaataa atctatattt gtcttaatac
      841 agcctcatat aaaacttctc caataggttt atttattaca agagaagctg acttatcata
      901 gactgtattt gctttattaa taagagcaat ataatcacct ttgtaataat ctataaaact
      961 tgctgctggg tacacagcta atgatgtacc tcctataatc aataaatcag cattacttat
     1021 agcagaaatt gttttagtaa tgacatcact gtcaagagct tcctcataaa gtactacatc
     1081 tggttttact atagaaccac agttgtcaca gtaaggaata ttacctccca gatttaacat
     1141 agattctaag tcaaaaaact taccacattt agtacaataa tttctatgta cagaaccatg
     1201 aagttctagc acatttttac ttccagccat ttgatgaagt ccatcaatat tttgagttat
     1261 gacagcttta agcttaccca tttcttcgag ttttgctaaa gctatatgag cattattggg
     1321 ttttgcatta ggatatatta atttatcctt ataaaattca aaaaattctt ctggatatct
     1381 aacaaaaaaa gtatgtgaaa ctaattgttc agcagtaaat tgtttattga gtttttggct
     1441 aaataatcca gtagaacttc taaagtctgg aatattagat tcagttgaaa cacctgctcc
     1501 accaaaaaat acaatattat tgtgattagc tattaagtct tttaagctat ttgcatccat
     1561 agttacacct ccaaattatt atatataaat tgtactacat attaggtcgt ttatgtttta
     1621 ttaatttaaa taaatatata gtttaataag ttaaataaag ggaatataaa taaaatgtat
     1681 acagagtata aatagacaat atttactaaa ataacaagtt gtcgtataat tatattaaaa
     1741 ttgttttagt gtataagaag ggcgggggaa gtacgtgaag aaaaaagcag ctttagcaac
     1801 attggctatg ttacccttag gtgtggtaaa tgcacatgct gatggagata taggtatagt
     1861 gactataaat tatttaaatg taagaaatga accaactgcc gaaagtagca tagcctttgt
     1921 tgctaaaaaa gatgataaag ttttgattaa agactcttct aatggatggt ataaaataaa
     1981 agctgaatct ggacaagaag gttgggcttc atcaaaatat atagcaaaat caaatagtga
     2041 ctctttaaga acgtctacaa ataaagaaaa acaagttatt tcaaatagtt taaatatgag
     2101 aaatggagca ggtacaagtt acagagtaat aactgtacta aaaaaaggtc aaaaagtaga
     2161 agtaatatca gagagtaatg gatggtctaa aatcaaatat gatggaagac taggatatgt
     2221 atctagctct tatttaggag acgtttcaaa ctcaactaat aaatcaaaaa ctaaacaagt
     2281 gaatacaact tcactaaatg taaggagtgg accaaataca agttatggtt tgttaggcaa
     2341 gttgccaaaa ggaagtaaag tagaagtaat atcagaaagt aatggatggt ccaaaataaa
     2401 gtataatgga aaagatgcct atgtatctag tatgtactta tcggatgtaa gtcaaagtaa
     2461 ttcagacaat tctagtcaaa gcaatgataa aaagaatact gataaggttg taaatacagc
     2521 ttctttaaat gtaagaagtg gaccaggttc tacatatagt aagttgggaa aagtttataa
     2581 aggaagtaaa gtaactgtac tatcagaaag tagtggatgg gctaagatta attttaacaa
     2641 taaagaagca tttgtagtag gcaattattt atctacctca gcagatactt caaataataa
     2701 ctcaaatagt aactctgata acagttctaa tagtaatggt aataattctt catcatcagg
     2761 ccaagtaaat ggtatgtcag gtataagtgg ggctaaaatt gattataaat ctttgagtta
     2821 tactttagaa tctcatataa gtaaacaagt tgagaaagca gcatcaggag gaaatgtgat
     2881 agctccaagt aataggaaaa gtactccaag tcctgagttt agtacttttt cagctcaaag
     2941 aacaagctca tttgtaaatg caagttcaag tgatatagaa tattatttaa atcctaagaa
     3001 ttttacaaat actactaaag gtatgatgca gtttttaaag attaacagtt atagagatgg
     3061 tatttcagaa tcaagtctta actcgtatct taatggttta tcttctagtg tatttaaaaa
     3121 ccagggagca gcctttataa atgctgccaa gaagtataat atagatgttg tatatctagt
     3181 atctcatgct atgtgggaaa ctgcttatgg taagtctaca cttgcccaag gtcaaacatt
     3241 aacatcttat aagggacaac ctcttagtaa gccagttaaa gtatacaatt tttttggtat
     3301 aggagcaata gataaaagtg ctaatgtttc aggtgcagaa gcagcgtatt ccaatggctg
     3361 gactagtgta gaagctacaa tagatggctc tgcaaagtgg atatcacaaa attacgtaaa
     3421 tagttctaag tacaatcaga atactatcta caagatgaag tggaattatg attatacatg
     3481 gcatcagtat gcaactgatg taaactgggc taatggaatt tctggaatta tggaaaattt
     3541 aattggtctt tatggaggag gaagtagttt ggtttttgaa gttcctcaat ataagtaata
     3601 cataaataaa aaatatagac tatgggtagt tttcatttta tttaaattat ctatagtctt
     3661 tttgtatata atttataatc tgtaaattta atgttaacaa aacttttatg ttataatatt
     3721 aattctaagt aaatataagt gagtaatagg tagaaataga taaaaagtgg taataatata
     3781 tataaagata attttgagaa aggaggatat atatggaaag tattaaggaa tatttggata
     3841 agttagaaat taataatagt ggtcttggaa agcaacttaa agaagtttat ataaatagag
     3901 tagtttattt taaggaagat aagatagttt atttttatct aacttctaaa gatattgttt
     3961 ctcatgaact tttagataaa tttaaagaag aattgatgta taaactcgat tattttaaag
     4021 atatgaggat gaagataaga tttactggtc ttgaaagaaa atccaataaa gatgttataa
     4081 aaaaatattg gaataatata ttgtatatat taaagtatct ttgtccatct attgcagggt
     4141 ggtataaaca agtagaattt ctttgtttag aagaagaatt aaaaataaaa cttccaaaag
     4201 gtatatttta tgagcgatta atgaaaaaaa atgtaactta tgtacttaaa accgtgctta
     4261 gcgaagagtt gggattagat ttaaatataa caatagaaaa agctgttgat gaaaaggtaa
     4321 ataaagaaag actcataaga atcaatgata gagaaatgga agaaaaaatt agggctttag
     4381 aaattggaaa agttaataac tgtgaagaaa atgaagagga aagctatgtc attaagtctg
     4441 atgtagatga aaatttaatc tatggagata atgcaaatgc tatgattgaa aatatagttg
     4501 aattaaatgc atcttctgga acagttgcag ttgttggaga tatatttgat gttgacacta
     4561 aagaacttaa aaacggaaaa atacttatga tagcttcaat tacagattat actagctcaa
     4621 taagctgtaa acttttttta acagatacaa ataaggatgg agtacttgaa aatgttaaaa
     4681 aaggagcata cttaaaaatc aagggtgaca tagtttatga tacatatcaa agagaaatta
     4741 gtatgatgat tagtgggata agaaaagaaa ctagaataga gagagaagat aaatcagagg
     4801 aaaaaagagt agaactccat gcacatacac aaatgtcttc tatggatgct atttgttctg
     4861 ttaaaaagct tgtagagcgt gcagccaaat ggggtcattc tgctattgct ataacagacc
     4921 atggtgttgt acaaggattt ccagatgcta tgaatgcagg taagtcaaat aatataaaaa
     4981 tactttatgg agtagaaggg tacctggttg aagatgattc tctcattata gaggatgcaa
     5041 atgataaaga actttcgcag acatttgttg tatttgacat agagacaact ggcttttcta
     5101 atacaaatga taaaataact gagattggtg ctgtaaaaat agaaaacttt aagattgtag
     5161 atagatttag tgagttaata aatcctgaaa aagatatttc ttataagata caggaattga
     5221 caggaataac taatgaatta attaaagaca agccaaccat tgaagaagtt cttcctaagt
     5281 ttatggaatt tgttggagat agtgtattag tagcacataa tgcagagttt gatactggat
     5341 ttatatcgca aaaatgtagg gaacaaggct tgttatataa taacaaaaaa gtagatacac
     5401 ttatgttagc aagagtaatg ttgccaaact taaaaagaca tagattaaat gtcgttgcaa
     5461 aagaacttgg tattcctctt ttaaatcacc atagagcagt ggatgatgct gaagctacag
     5521 cacttatatt taataagttt ttgcagatgc ttacagaaaa aggtgcaaaa actctaagtg
     5581 atgtaaacaa tatacttgga aagattgatt acacaaagct tagcacaaat catataacct
     5641 tgatagcaaa aaattctata ggtataaaaa atttatataa aataatttca gatgcacatg
     5701 taaatcattt ttttagagca ccaagaatcc ttagaagtgt attaaatgaa tataaagaag
     5761 gattaataat tggttcggct tgtgaagctg gggtggtttt tcaagctgta aagaaaaacg
     5821 tgtctgatga ggaaatgaaa aaaataatag atttatacga ttatattgaa gtaatgccta
     5881 tagataataa tagatttatg attgataaag gagaagtaaa ggacgaagaa gagttaaggg
     5941 agttgaatag gaaactaatt gatacagcca aaaaatttga caaaattcca gtagctactg
     6001 gggatgttca ttttttagac aaacatgaag ctgtcttaag aaaagttctt aaatattctc
     6061 aaggttttaa agtagatgaa gaagaaactt atttacattt tagaacaaca gatgaaatgt
     6121 tggaagagtt tagttatctt ggagaagaat tggcatatga agttgtagtt gaaaatagta
     6181 atctgattgc cgatatggtt gaagatataa aacctatacc agatgatact tatcctccaa
     6241 ttatagaggg ctcagatgtg gagttaagag aaatgtgtta caaaaaagcc aaacgaatct
     6301 atggagaccc aataccagaa atagttcaaa aaagactgga tagagaatta aattcaataa
     6361 taagcaatgg gtatgcagtt atgtatatta tagctcaaaa actggttgca aaatctcttt
     6421 cagatggata tttagttggt tcaagaggct cagttggctc atcttttgca gctactatga
     6481 gtgatataac agaagttaat cctcttccag cacattatat ttgtgaaaac gaagactgta
     6541 aatattcatt cttttatgaa ataggtgaat ggggctcagg tgttgattta ccagacaagg
     6601 attgtccaaa gtgtggaaga aaacttgcta aaaacggtca tgatattcca tttgaggttt
     6661 tcttaggttt tgaaggtgat aaggaaccag atatagactt aaatttctca ggaaattatc
     6721 agccaacaat tcataaatac acagaagaac tatttggaga ggggtatgta tatagggctg
     6781 ggactatagg tactgtagca gaaaaaacag cttttggata cgcaagaaaa tatgtggaag
     6841 aaaataatat aagtgtacca aatgcagaag tacttaggct ttcaaatgga tgtactggag
     6901 taaaaagaac ctcaggacaa catcctggtg gagttatggt tataccagac tataaagatg
     6961 tatacgattt tacacctata cagtatccag caaatgatac ttcttgtggt gttataacta
     7021 ctcactttga ttatcattca ataagtggta gaatacttaa acttgatata cttggacacg
     7081 acggtcctac cattataagg atgcttgaag atatgactgg aataaatata acagaaattc
     7141 ctttagatga taaagagact atgtctctat ttacatctac agaagcatta ggtgttacac
     7201 cagaagaaat aaactgtcct ataggttgcc ttgctgtacc agagtttgga actaagtttg
     7261 tacgacaaat gttacttgac acaaaaccta ctacatttgc agaacttgta cgtatatctg
     7321 gtctctctca tgggacagat gtttgggtaa ataatgcaca agacttagtt agagaagata
     7381 tagttggatt aaaagatgtt atatctacac gagatgacat aatgaactat ttaatattta
     7441 aaggattacc tcccaaaatg agctttacaa taatggagag tgtaagaaaa ggtaaaggtt
     7501 taaaaccaga acacattgaa gaaatgaaaa aaaataatgt tccagaatgg tatataggct
     7561 catgtaaaaa gattaagtac atgttcccaa aagcacatgc tgttgcttat gtaatgacat
     7621 catttagaat tgcatattgt aaagttcact atccagaagc attttatgcg acttatttta
     7681 cgacaaaagt tgaggatttt gatgcagatt taattgttaa aggattagat gctataaaat
     7741 caaaaataaa tgaaattgag tcactgggaa atgatgcaac cacaaaagaa aaaggtatgt
     7801 tgaccgtttt agaagttgct cttgaaatgt atgctagagg aataaaatta ttaccagttg
     7861 atatatataa atcagatgca actgagttta tagttgtagg agaaaaaaca ttacttccac
     7921 caatggcagc aatacaaggt cttggaggaa atgcggctat aaacatccaa aatgaaagaa
     7981 aaaatggtga atttatatca aaagaagatt tgagaaagag aacaaaaata tcaaaaacgg
     8041 taatagaaac tcttactaat catggttcac ttgagaatat gagtgagaga aatcaattgt
     8101 cattgtttta agttagccca aaaagttgca aataaaagaa ttttatgata tcatagtata
     8161 gaaaatagta tactttgcag aaactaagag tgagacagct gttctcactc ttttatttta
     8221 aatatattat taaaaagctg gtttattttt attaaatata ttttatttaa gattatataa
     8281 actggtcatt tacaattgaa taggaggaac tttaatgaaa aaaaatttag aagctacaat
     8341 tgaggagatt gtaactaaaa taacggatga acatggattt gaaatggttg atgttgaata
     8401 tgtaaaagaa gcaggagaat actacttaag agtatacata gataaagaag aaggaatatc
     8461 tttaaatgaa tgtgaattag ttagtagaga attaagtcca atactagatg aaaaagaccc
     8521 tataaaagaa aattactttt tagaggtatc ttctccaggg cttgatagag cattaaaaaa
     8581 agacagagat tttgttagat atcaaggtag agatgtagat ttaaaattat ataaaccatt
     8641 aaatggatgt aagcaatttg aaggtgaact tgtaggatta acagaagata ataatataaa
     8701 aatcattgca aatggtaagg aaatggaatt taatagaaaa gatgttgcta ttgtcagatt
     8761 agcaataaag ttttagtggt atattaaata gggaggatat aaaaaatgaa tcatgaattt
     8821 atggaagcat tagatgaatt agtagttgac agaggtatag ataaagaaat acttatagat
     8881 actatagaac aagctctttt aactgcatac aagaaaaact ttggttcagc acaaaatgtt
     8941 agagttgaat ttgatagaga caagggagat ataaaagtat tttctcaaag agttgttgtt
     9001 gatgaatcag atttatatga tactttctta gaaatagagt tagcagatgc tagagagata
     9061 aatcctaatt atgaattagg tgatattata gaacatgaag ttacacctaa aaactttgga
     9121 agaattgcag ctcaaacagc aaagcaagta gttgttcaaa gaataaggga agctgagaga
     9181 gaaatagtgt ataatgaatt tatagaaaaa gaaaatgaaa tagttacagg agaggttgct
     9241 agagcaaata aaaatgttgt ttatgtaaat cttggaagaa tagaaggtat aatgactcaa
     9301 agtgaacaaa taccatttga gaattataaa gcaggtcaaa aaataaaatt ctatatactt
     9361 gaagttaaaa agactaacaa aggacctcaa atagttgtat caagaagtca tccgggtcta
     9421 gtaaagagat tgtttgaaga agaagttcct gaaatatatg aaggaatagt tcaaataaaa
     9481 tctgtagcaa gagaagcagg gtcaagaact aaaatggcag taagatctat agatgaaaaa
     9541 atagacccaa ttggagcttg tgttggacca aaaggactta gagtaaaaaa tatagtggat
     9601 gaacttggcg atgagaaaat agatataata aaatatagtg aagacccagc agagtttata
     9661 tcagcagcac ttagcccatc aaaggttgtt agagtagata tagatgaaga tgaaaagtct
     9721 gccttagtaa tcgttccaga ttatcagtta tcgcttgcta taggtaaaga aggtcaaaat
     9781 gcaagactag cagcaaaatt gactaactgg aaaatagata ttaagagcga atctcaagca
     9841 gaacaagaaa tgttaaatct tgaaaattcc aaagaaatag aagctgagga tgttgaagct
     9901 gaatttatcg accaagaaga gttagatact tcagaggata attttagtga agaagagtaa
     9961 ggagggatga ttttgaaaaa agtaaaaaaa gtgcctcaaa gaaaatgcat agcatgtcaa
    10021 gatagagact ctaaaaaaga gcttataaga atagttaaaa ataaagaagg aaaaatattt
    10081 ttagacccaa caggaagagc caatggaaga ggagcatatg tatgtaaaag ctctgaatgt
    10141 ctaaaaaaag ctataaagag taaagcatta aataaagctt ttaaaataga tgttcctgat
    10201 gaagtctatg ataatctact tatggagtta gaagaatatg aaaaataata aagaaaaagt
    10261 actttcgttc ttagggctcg caactcgtgc agggaaaata gtgtctggtg atgattcaac
    10321 tttgcttgac cttaaaaaag gaaaagtaaa tttgatttta atcgcagaag atgcatcaaa
    10381 taatactaaa aaacttttta aagataaatc aacttttaga aatattccat atctattttt
    10441 ttcaacaaaa gaggaaatag gatttgcaat aggaaaatct ccaagagcag ttgtaggaat
    10501 aaaagatgaa aatttttcta aaaagataat tgaactaata gaaatttaaa ataaaatagg
    10561 gggtgatctt gtgtcaaaaa caagagtata ccaaatagca gaagaattaa atatatcaaa
    10621 tgaagagctt ataaataagt tagctgaatt agatataaat gtaactgaca aagattcagt
    10681 attagaaggt gaagagttag aattagcact tgaaatgtta ggtgaagatt tatctcaaga
    10741 aaatggaaat gttatagaaa tagatggaaa gttgacagta caagtattag caacgaaatt
    10801 agataaatct ccatcagaaa taattatgaa gcttatgaaa atgggaacta tggcaacaat
    10861 aaatcaagag ataagttttg agattgctgc tttggctgcc aaagactatg gatttgaatt
    10921 aacagtagct gaaagtgatg atacagaagc tttagaaata gaagctttaa tggaaattga
    10981 agaagacaaa gaagaggatt taaaacctag accaccagtt gttacagtta tgggacatgt
    11041 tgaccatggt aagacatctt tactagatgc aataagaaaa actgatgtga tctcaggtga
    11101 agctggagga ataactcagc atataggtgc ttcagaagtt aaaatcaatg gacacaaaat
    11161 agtattttta gatactccag gacatgaggc tttcacatca atgagagcaa gaggagcaca
    11221 agttacagat atagcaatat tagtagttgc agcagatgat ggtataatgc ctcaaacagt
    11281 tgaagctata aaccatgcta aagcagcagg tgtaccttta atagttgcta ttaataaaat
    11341 agataaacca ggtgcaaacc cagataaggt taaacaggaa ttagcagacc aaggattatt
    11401 agttgaagac tggggtggag aagtaatagc agttccagta tcagctaaga aaaaagaagg
    11461 aatagataca cttttagaaa tggtattatt ggttgctgaa atggaagagt taagagctaa
    11521 tccaaataaa agagcagtag gaactgttat agaagctgag cttgataaag gaagagggcc
    11581 agttgcaaca gtacttgttc aaggtggtac tttaacagta ggtgacccaa tcgttgcagg
    11641 tgttgcatgt ggtaaagtta gagcaatgat aaatgcaaaa ggtaagagag taaaaacagc
    11701 aggaccatct acagcagtcg agatattagg tctatcagaa gttccacaag gaggagacca
    11761 atttgtcgaa gttccaactg ataagattgc tagaagtgta gcagcaagaa gacaacaaat
    11821 agttagagat gaaatgttaa aatcaactca aagattatca ctagatgctc tatttagtca
    11881 aatgagtgaa ggttctataa aagaccttaa tatagttata aaagcagatg tacaaggttc
    11941 agtacaggca gttaaacaat ctttagaaaa attatcaaat gaagaagttc aagttaaagt
    12001 aatacatggt ggtgttggag ctgtaacaga atcagacata ttacttgcag cagcttctaa
    12061 cgcaataata ataggattca atgtaagacc agttccaggt gcagaatctc taggagaaaa
    12121 agaaaatgtt gatataagaa catatactat aatatacaag gcaatagaag atatacaagc
    12181 ggctatgact ggtatgttag accctgaata tgttgatgaa gaaacaggaa aagctgaaat
    12241 aagagaaata tataaaatat ctggtgttgg aacagtagct ggatgttatg tgactaatgg
    12301 taagatattt agaaattgta aagtaagatt agttagagat agcataataa tacatgaagg
    12361 tgagcttgca gcacttaaga gatttaaaga tgatgtaaaa gaagttaatt ctggatacga
    12421 atgtggtatg agttttgtaa attataacga cataaaagaa ggcgatatag tagaagctta
    12481 tataactaaa gaagtagaaa gaaaattata aattcgtatc aaagaaaatc agttagtaaa
    12541 gaaggtcgat ggtatggcat catataatag aacaagaagg atagcagaag aaataagaaa
    12601 agtcgtaagt actatgctta taaatggagt aaaagaccct agaataacat ctatggtgag
    12661 tgtaactgat gtagaagtta caaatgacct aagatatgct tatgtatatg taagtattct
    12721 aggcggagat gaagaatcca cactaacagg tcttaaaagt gctggaggat atataagaag
    12781 agaagtagga aaaaatataa aacttagata tattcctgag atagtattta aacttgatga
    12841 ttcaatagaa aaaggaatgt atatggatag ccttataaaa agagttaatg aaaaaaatgc
    12901 tcaacaaaat gaggatgaaa attatgatga ataatatgga tagtattata aactatattt
    12961 atgagggtga ctattttata gttacctctc atatcagtcc agatggagac aatattggtt
    13021 ctacactttc aatgtattat acattgaaga atttaggaaa aaatgtatat tatgtacttg
    13081 atgatgaagc tccattaaat ttaaggtttt tggttgaagg tgtaaaaatc tataagtcta
    13141 atgaatttaa tatgaagaac tattctctaa ttgcacttga ttgtggggat aagatgagaa
    13201 tatgtgtgag tgatgaaatc aaaaataatg catcaaaatt aatctgtatt gaccatcatg
    13261 ctagtaatga ttcatatgga gatttaaatt atgtagatat tgatgcatct tctacatgtg
    13321 aattagttta taatttatta gttagatttc agcaaataaa agatattaat attataaatg
    13381 aagatatagc aacatgttta tatacaggtc ttgtaactga tactggaaac ttttcgtatt
    13441 caaatgtaca tgcaagtagc tttgaaatgg caaaaaattt acttgtttta ggtgcacaaa
    13501 aaaatactat aatacaaaat atatatcaaa gcaattcttc tggttattac aaattattag
    13561 gagaagctct aaagggtttg gagatatttg attaaaaaat agttacgcac actcgtgact
    13621 ttagtcatga gttagtagct aaaatagtca gcatataggg aaacttatat gtagagatag
    13681 gataaaacct atccaatact acttgaattg ctggaaaccc ct
//
LOCUS       DAGQVA010000099        13293 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.099, whole genome shotgun sequence.
ACCESSION   DAGQVA010000099 DAGQVA010000000
VERSION     DAGQVA010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.099"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..186
                     /locus_tag="MIV85_003313"
     CDS             <1..186
                     /locus_tag="MIV85_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBY2962632.1"
                     /translation="DTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIG
                     DILLDNEGDLLYFNNIN"
     gene            197..2518
                     /locus_tag="MIV85_003314"
     CDS             197..2518
                     /locus_tag="MIV85_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBY2962633.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTYLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLAELTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFANSDRNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            2533..3084
                     /gene="cas4"
                     /locus_tag="MIV85_003315"
     CDS             2533..3084
                     /gene="cas4"
                     /locus_tag="MIV85_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBY2962634.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            3087..4067
                     /gene="cas1b"
                     /locus_tag="MIV85_003316"
     CDS             3087..4067
                     /gene="cas1b"
                     /locus_tag="MIV85_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBY2962635.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            4070..4336
                     /gene="cas2"
                     /locus_tag="MIV85_003317"
     CDS             4070..4336
                     /gene="cas2"
                     /locus_tag="MIV85_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBY2962636.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   4520..6183
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4520..4548
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            6244..6672
                     /locus_tag="MIV85_003318"
     CDS             6244..6672
                     /locus_tag="MIV85_003318"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBY2962637.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(7127..7906)
                     /locus_tag="MIV85_003319"
     CDS             complement(7127..7906)
                     /locus_tag="MIV85_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962638.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            8230..8775
                     /locus_tag="MIV85_003320"
     CDS             8230..8775
                     /locus_tag="MIV85_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBY2962639.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            8807..9943
                     /locus_tag="MIV85_003321"
     CDS             8807..9943
                     /locus_tag="MIV85_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBY2962640.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            9947..11338
                     /locus_tag="MIV85_003322"
     CDS             9947..11338
                     /locus_tag="MIV85_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBY2962641.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRIIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            11414..12289
                     /gene="dpsA"
                     /locus_tag="MIV85_003323"
     CDS             11414..12289
                     /gene="dpsA"
                     /locus_tag="MIV85_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBY2962642.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            12292..12882
                     /locus_tag="MIV85_003324"
     CDS             12292..12882
                     /locus_tag="MIV85_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBY2962643.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
BASE COUNT         5277 a         1368 c         2087 g         4561 t
ORIGIN      
        1 gatacagata tagatggtat aagttacaga ctcaataatt actatgataa taatgctgtg
       61 gaagataaaa aaagggtttg gaataaggta gatagttatt atgttgagga tggaaatact
      121 atatcaattg gagatatatt attagataat gaaggagatt tattatattt taataatata
      181 aattaggagg gagattatgt tatatgctaa atctaatcca gtggaaacac ttagagaaca
      241 tactgatgaa cttttaaaac aaatgaatgt attaagagaa agttatggaa aaaatataaa
      301 tagcttagat tttctagaag aggagatatt ttggcaatta cttgactttg ttatagaatt
      361 tcatgatatt ggaaaagcat tttcaccgtt tcaagagtta ataaaaagca gaatggatac
      421 taaaataaat gaacctaaaa tagtaactta tttagaaaat aatgtaggcc ataattatct
      481 ttctcctgca tttattgatt atagttatat agacaggaaa aaaaataaag aacttagagc
      541 agtattaaat caagttattg tatatcatca tgaaagagat atctttatag ataaagattt
      601 taaaaattta atacaaaaaa tattagatga agatttaata aataaagttt atgaactaca
      661 gcatgaattt aaagttagat atccaataaa aacagaaaaa ttgagtaaag tatatctaca
      721 aagtgtagaa aaaagaatag ataaaaatca caagtactat aatttatata ttatgttaaa
      781 aggaatacta catagactag accatagtgc ttctgctcat gaagttgtgg aatgcaataa
      841 tgttataaat ataggagaac agacagaaaa ttatttaatg aaagagtttg gtagtttgag
      901 agaggctcaa tcatttgcta aatctaatag aaataagaat ataatactga ttgcatctac
      961 aggaatggga aaaacagaaa ctgccttaat ttggatagat aaagacaagg cattttttac
     1021 acttccatta agagtaagta taaatgcatt atttgataga gcaaaaaata tagttggtgt
     1081 tggagaatca aatgatacat tcttaggttt gttacattca acagcaatag attatctaga
     1141 agaaagtaat caagaaaatt caagtgagat tgtagattta gcaaagttat tatcttgcaa
     1201 actgacattt tctacaatag accaaatatt taaatttcct tttttgtata gagggtatga
     1261 aaaagtgtac tcaacattag catattcaaa agtagtaata gatgagatac aagcatattc
     1321 accagaaata gcagctgtat tggtaaaagg tatagaaatg atacataaga taggtggcag
     1381 atttatgata atgacagcta ctatgccaac catatatata gatgaattaa aaaaaagagg
     1441 tgtaatgaat agtaacttag ctgaattgac atgtaataca gaaaaaataa gacattgtgt
     1501 ttctattgta gaaaattcaa tagatgaaaa cttaggtaaa ataatacaaa gtggaatgaa
     1561 taaaaaagtt cttgtaatag taaatacagt taaaagtgct gtagaaaaat atgagttaat
     1621 agaagaaata gttaaaccaa aaggaataga tgtcaactta aatcttttac attctatgta
     1681 tatacaagaa gatagagcaa aattagaaaa atatataaaa gaatttgcca atagtgatag
     1741 aaatggaatt tggattacaa cacaattagt agaggcatct cttgatattg attttgatga
     1801 gcttcataca gaaaattcaa cacttgacag tctatttcaa cgatttggta gatgttatag
     1861 aagtcgtgag tatgaagaaa atagcccaaa tatatttata tatacagaaa aagctacagg
     1921 aataggtagt atttatgata aggatattgt agaaaaagga cttgagctac tgaaaacttt
     1981 tataaatgga aaagaatgtg tgaagatgaa agaaaaatat aaggtagaaa tggttaagat
     2041 actatactct aaagaaagtc tagaaggtac agcttttgaa aagagattta ccagtgcttt
     2101 aaatatttta gatactataa cgccatatag tttaggttct aaagatgcac aaaatatact
     2161 tagaaatatt gaaggatata cagtaattcc agaggatata tataataaaa ttgaagaaac
     2221 tttaatcaaa gattatgaag agttgggaca agagcttata aatgcatata gtaatgatga
     2281 tagacaattg ataaataaaa taaagtctaa gagaaaaaaa gcaagaagag agataattaa
     2341 aaaaactgta aatttaccaa tatataaagc taaacaaaat gtaattgaca tacaggtgaa
     2401 aggtcttgaa gatttaaaaa tacttttata taaatatgat atatacgaaa ataagcatac
     2461 aaaacagata tttggtaaag gtgtgcttat aagtaatgaa atagaccaat ttatttgatt
     2521 tttatattaa caatgtggct aaaatttact aaagaaggtg attttgtgcc aatagattta
     2581 gaagtattaa aagttcaagg tgtaaaaata aattattatt atgtatgtaa aagaaaacta
     2641 tggctatttt ctaaaggaat aaccatggaa caaaatagta gtagagtatt gtctgggaag
     2701 atagtacatg aagattcata taaaagaatg aaaaataaag aaatattgat tgatgatatc
     2761 ttgaagctag atataataaa ggatgagtat gtaaaagaag taaaaataag ttcaaagatg
     2821 aaagaagcag atgaaatgca gttatactat tacttatact atttaaagaa tagtatgggt
     2881 atagagaaaa aaggtactat aaattatgtt aaggaaaaga aacaagaaga attgatattg
     2941 acagaagaaa aagaaagaat tattgaaaac acacttataa atataaatga aataaatatg
     3001 cagttatctc ctcccaaaat tgagaaaaaa cattattgta caaaatgtgc ttattatgaa
     3061 ttttgttttg tgaaggagga gtaacaatgt ataaagacta ttatattata agtaatgggg
     3121 atataaaaag gaaagaaaat acgatttact attacaattt agaaggtgag aaaaaaatat
     3181 taccagtaga acaagttgat gatattcata tatatggaga agtagattta aatacaaaac
     3241 ttataaatta cataagcaaa tatggggtga tgcttcattt ctacaattac tatggatatt
     3301 attcaggtac atattatcca aggaagaaaa atgtatcagg attcagttta gtatgtcaat
     3361 cagcctgcta tttagataaa aatgaaagat tatacttagc aaaatccttt gtggaaagtg
     3421 catcatacca tattttaaga aatatgagat attacaaagt tgatgaaagt ttaattgata
     3481 ctataaagga tgaactaaat gatttgaatg atgtcaaaga aatatcagaa cttatgggta
     3541 aagaaggcag aataagaaaa acatactata aatcatttaa tcaaatatta aaagatgatt
     3601 ttgaatttta taaaagagaa aaaagacctc ccaaagaccc agtaaatgct cttatgtctt
     3661 ttggaaatag cataatgtat acgaatgttt taagtgagat atataagaca caacttgacc
     3721 ctacaataag ctttttacat gaaccatcaa caaagagatt ttctttaagt ttagatattg
     3781 cagaaatttt taagccaatt ataattgaca caataatttt tagcctgatt aataataaaa
     3841 gaattaataa gaatgatttt gaatatcaag acaaaatttg ttatttaagt gaaaaaggaa
     3901 agaagaaatt tttgcaagaa tttgaaaata agatgcagac aactataaaa catagaaatc
     3961 taaatagaaa agtttcatat agaatgttta taaggttaga gtgttataaa ttaattaaac
     4021 attttataaa tgatgaaagg tacaaagttt taaaggtgtg gtggtaagta tgtttgttat
     4081 tgttacttat gatattgttg aagcaaggtc gttaaataga attagaagga tacttagaaa
     4141 atatttgact tggacgcaaa attctgtttt tgaaggcaat attactgaag gaaagttaca
     4201 taaatgtatt tctgaaatag aaaatattat tgataatagc gaggattcaa tctatgttta
     4261 tgagataaaa aatcctaatt caattaaaaa gaaatgttat gggattgata agtattctga
     4321 tgaaatgttt atataggttt gcagtgagcg atatttatgc taaaataggt gttaacagtt
     4381 ggaatataag ggattgaagg tgtatgataa ttgttatcaa ttgcactact gctcgctcac
     4441 tgcaaatttt gatgttttta ttgaattata attgcttgat tgaagtgttt tcaatgtatt
     4501 caaatatacc tattttgggg ttttatatta actaagtggt atgtaaataa ttttttcgga
     4561 tatttaataa tttattttaa atttagtttt atattaacta agtggtatgt aaattaattt
     4621 agggtaactt ttatattatt ttcttctatc gttttatatt aactaagtgg tatgtaaatt
     4681 tggttgatat agatattagt cctattattt ctgcttgttt tatattaact aagtggtatg
     4741 taaataaatt agataattta taagtcaata aaataagtcc aagttttata ttaactaagt
     4801 ggtatgtaaa taaatttgta atattatata atcatcctaa aacaaaaggt tttatattaa
     4861 ctaagtggta tgtaaattcg aatgctataa ttttaatata taaaataaat ggagttttat
     4921 attaactaag tggtatgtaa atatggattt tagtcgtttt taaatttttc tcgtaatagt
     4981 tttatattaa ctaagtggta tgtaaatacc attcatttat atttttatct gtatctctta
     5041 gccatgtttt atattaacta agtggtatgt aaattaagtt ttcttaaaaa agtacttgct
     5101 ttaaatatgt tttatattaa ctaagtggta tgtaaatttt attttctctt tattagtcat
     5161 tagtttttgc cttcgtttta tattaactaa gtggtatgta aatatgaaga atttgcgaaa
     5221 ctaataagaa aagatattga gttttatatt aactaagtgg tatgtaaatc tttctttatc
     5281 aaagtaagct aaatttagtt cctccgtttt atattaacta agtggtatgt aaatcgtcat
     5341 tactttttat tgcttccatt aaatttgttc gttttatatt aactaagtgg tatgtaaata
     5401 tcgcaagata ggctaaatct atcaaggaga gttgagtttt atattaacta agtggtatgt
     5461 aaatgactct gccatccctg taacaaacag tcttaccgca agttttatat taactaagtg
     5521 gtatgtaaat aaatatttta cgattagttg atgctataat tctattagtt ttatattaac
     5581 taagtggtat gtaaattctt ttgatttagc gttgtttgtc cggaatttta aagttttata
     5641 ttaactaagt ggtatgtaaa ttcgggctag aatgtatttt aaaccctagt tcattgaagt
     5701 tttatattaa ctaagtggta tgtaaatttt ctaatatcgc tatttaaact caatgcttca
     5761 tttgttttat attaactaag tggtatgtaa attcagaaca aattaaatat gtttcgtttt
     5821 ccatgtaagg ttttatatta actaagtggt atgtaaatag aactttttta tattagaagt
     5881 acttgacatg attgccgttt tatattaact aagtggtatg taaatcttga taatatttca
     5941 gcatatgata ctgaagatgg ttttatatta actaagtggt atgtaaattt gccaatgtaa
     6001 catctttaga tattacagta tcattgtttt atattaacta agtggtagat aagtagaata
     6061 ttagcaatat caacgagtat ttagaaactt attttatatt aataaagcag tatataaaat
     6121 tgtagaatca acaatagcat atactaaaac atccacctta tattaactaa atcatatcta
     6181 aataaaataa acttacctat aaacattata aaatcaatac aaaaatgagg tgaaataaaa
     6241 tttatgataa agaaattaaa caataaagat ataaataaaa tcatggaaat atgggaaaaa
     6301 agtacaatca aagcacatga ctttataagt aaagaatact ggcaaaataa ctataatact
     6361 gttaaaaacg aatatatacc tatatcagat acatttgtat atgatgatgg agatgaaata
     6421 aaaggattta taagcataat agataaaagc tttataggag ctttatttat aaagcccaaa
     6481 taccaaaatc taggtatcgg aggtaaactt ttagattatg caactaaaaa atataaaagt
     6541 ctaagcttag cagtatataa agataataaa aaagcagttg tgttttataa taaaaaaggt
     6601 tttaatatag taaaagaaca agtaaatgaa gattcaggat ttaaagagta cataatggaa
     6661 tatagtaaat aatatgatta cattctatta aaaggataat taatttattt gccatttgat
     6721 tttttaagag taatttttaa aatagactat atgaagataa agatatttat tatagatgta
     6781 agttaatcag aattgatata gctacaaaag aggaaaataa aattgtatgg tgtatttcag
     6841 atttaacaaa tttactattt aaagataata agtttgatat aatattaaag atactttcac
     6901 ctataaacta tagggtattt gaaagaattt taaataatta tggaatgcta ataaaggttt
     6961 gttaaaattt aataattatt agattataga aaattgccat gaaattagtt catcaagaac
     7021 tagtttcata gcaattttaa ttcttataag tgtatttatt tttacagatt taaaaaactt
     7081 atacagtatc taataatgta atcttattac tttagcctat aaatatttaa atcttaaaat
     7141 gttctctttg agataagttt atttcagagt cacaatttcc acaacagtaa gatgttgaga
     7201 catctttaaa tttttcagta ttctcatcaa agttcatttt tttctttgca ataattccta
     7261 ccttagttaa attagaacca caattattac agttttgaat tttgcatagg ttatatagtt
     7321 tatcaagtgt aatatcttct aataattcat cacaattaca acatctgata gaagaaactt
     7381 cactacacat ttcaataggt tcagcttctt tagaagaaaa tttatatgtt atgtcatttg
     7441 atactttata acctgtatca aatatattag aattacaact tggacataag tactttggaa
     7501 gatatatatc ttttttttca aaagtatcac tactaatatt acagtttaat tcatctaaaa
     7561 ttggtctttc atctaggtta ttacctttat ttaagcttag aagataatta taaatttttt
     7621 tatcttcatt ctgttttgat gtatctaaca aatgctccat tatattagtg tattttttgt
     7681 tttttgaagg catgtttaaa tccagataat tgttttcaat agcaaagcat actatattga
     7741 aatagttata tttaactgca aaaaataata acatttcatc aaatacttta tctattattt
     7801 tgtcagaaat acttatccaa aaatctggtg actctaagta aactttccta ctaagttcat
     7861 ctaactcttc atctatatta tttatattat tttcattaac tttcatatca tcacttcctt
     7921 ttaaatatct tgtgtataaa ctatttgtta ctatttttta tataaaataa aatcttatat
     7981 aaaaatatat catattataa tttacaagta tagtctaaat agagctgttt ttaagcaaag
     8041 ttttataaat gactattaaa atataaagta acagtataaa gtttacttat aaattaaatg
     8101 taaacctaaa tgcttataat agttgacaaa aaaacgtctt tattttatac taaaacaaag
     8161 ctttaataga agctttgtat atgtacatat aaactaaatg aaataagaca tatgaaggga
     8221 attataaaaa tgaaaaatac taaagtaaat attcaagatt taactaaaat gtcaatatgt
     8281 gtagcattat tgtgtatatc atcttacata tatataccat tgccatttac tccagcagga
     8341 gtaacagcac aaacaataat gataaattta atagctttga ttttaacacc aagacaagca
     8401 tttagtacag ttggtgtata tataatgata ggtttaattg ggattccagt atttggtgga
     8461 ggtacatctg gtattggaaa gttattaagc ccaacaggtg gtttttattt tgggtttttg
     8521 tttgcagcac taattattag tttattaaaa ggacgaaata atgatattaa gagatatata
     8581 ctaataacaa tttttgttgg aatgcctatt atatatttta tgggaacagt atttatgtgc
     8641 tattttaatc aaatgacagt agaagcagca ctttttgcag cagtagtacc atttttaatt
     8701 ggagatacaa taaagtcagt tattgcatct tttttaggca ctaaactgaa caatgtactc
     8761 agaagaaatc tatgataaat ctataatata aggaagggtg taatgtatga aggaagtttt
     8821 tatattagga ggattgagaa gtcatatagg tctaaaaaat ggaatttttc aatttgttca
     8881 acctgaatta ctaggagcaa gtgttttaaa agatttaatt aaaaagtatg aaattgataa
     8941 aattgatgag attatatgtg gaaatgcagt tgggacagga gggaatatag ctagattaat
     9001 gactttaaca gcaggagtgt caaatgaagt acctgctttt actgtggata tgcagtgtgc
     9061 ttctgctatg atgagtatag acatagcttt ttcaaaggtt aaatctggtc agtgtgattt
     9121 aattattgca ggtggttttg aaagtagttc tctacaacca atgcgcacat atcataagaa
     9181 tgataagcga tataatacaa ataatccaaa ttatacagtt gctcaatttt ctcctgatga
     9241 taatagccaa aatagtatgc tcgaaggtgc ggaaagagta gcagagttat atcaaattga
     9301 gaaagcagac ttggattttt gggtaaagga aagtcataaa agagcaaaag aagcaagaga
     9361 ggaaaaaata cttgaagata ttatatctcc tataaataat agtacctatg atgaaggtat
     9421 acgtgataag atgagtcaaa ggttattaga taggatgcca tcaattttag gaaaagaaac
     9481 tattacaaat gcagcaaatt catgtcttat taatgatgga gcttcattta ttataatatg
     9541 ttctaagaag tatttagaac atgtaaaaaa gaagcctaaa gcaaaaatta ttaatacatg
     9601 cacaatagga acagatgcaa ccttaagtcc aacatcagcg atacaagcaa tggataaact
     9661 tttagagata gaaagtctta attatttaga tgtatctgct gttgaattta atgaagcatt
     9721 tgcagttata gatgtgttgt ttcaaagaaa atatccagag ttaatagata gatataatat
     9781 atttggtgga gctttagcgt atggacatcc atatggtgct tcaggtgcaa ttattgcatt
     9841 acatctttta aaagcattag aaaagactaa gggtagatat ggaatttgct ctatagctgc
     9901 agctggtggt ctaggttcag ctttactgct tgaaagggtg tagattatga actattatga
     9961 acttttaaga ataaaaaaag agaggcataa aaataaaaat tttttaatta tagatggaga
    10021 aaaatatact tatgaaaata tattgagtta tagtgaggaa ctaggaaaac aaatttcttt
    10081 aggtgaaaat atcccaattt taatatattc taaaaatata atgtttcagt tgattagttt
    10141 ttttgctatt aattattcaa aaaatattcc tattatttgt cattataatc tttctaaaaa
    10201 agtattagat gatattttat taaaaaataa tatttcaatc attatatctg atgaatctat
    10261 ggacgttatt gatttatatg atgataacaa taatgaagta gcaaaaaaag ttaatttttc
    10321 tatttttaat cctaaattta atatatatat gtatcaatat aagaacctta taaattattt
    10381 agataaaagt atttgtatgg gagctttatc ttcaggttct acaagtgttc caaaggtatt
    10441 atatagaaca tatgagagtt gggctggatt ttttcctata caaaatggta tttttaatat
    10501 ctctggggaa tcaatcttgt ttgttaatgg aacacttagt tttacaggga atctaaattc
    10561 tataatgtca gtattatatg aaggaggtag tattgtaata agttcaggtc ttaattgtaa
    10621 atcatggata aggataataa aacaatataa tgtaactaac atatacctta tacctacaaa
    10681 acttcaactt ttggttaaac acttaaaaga accagtactc aaagttgtaa gtatttttac
    10741 agggtctcaa ttattatttg aagatactgc aagaaatcta aaaaaatata tgccaaagtc
    10801 tgaaattatt ttatactatg gggcaagtga attaaattat attacatatt tatgctatga
    10861 tgaactaatt gaaaaacctc taagtgtagg cagaccattt ccaggaatag atatatatat
    10921 tagagaagga aaaatttttg tgaatacaga atatgcagta tataatgcaa ccaaacctta
    10981 ttctgtcaat gatattggat attatgataa tgatggatac ttaatatttg aaggaagaag
    11041 tgatgacatt ttaaatattg gaggatttaa agttagttct actaagattg aaaatgaagt
    11101 taaaaaaatt cctcaaattg aagatgcaat tgtattgccg tactcagaca ctataagagg
    11161 aaatcaaatt gtattatttg taataactat agacaaaatt acgaagaaag atttgttgat
    11221 taaaatgaaa gataatctaa tgaaaaatga aatcccaaag aaaattatct ttttaaattc
    11281 atttccatat acctcttctg aaaagataga tagattagca ttattaaaaa tgttataagt
    11341 ataatattta gtaattttag tgaaccaatg tattgataaa aacatattgt atatagtaaa
    11401 ggaggcttac aatatgtcaa atcaatacga tataactgtt attgggggag acctgcgaca
    11461 agtgtacatg gtaaaaaaac taattaataa agggtattct gtagtcactt atgggatatc
    11521 aaatgaaatt ataaatggaa tcgttggaaa atcaacttca ctagctgaag cactatccaa
    11581 aagttccatt attttatgtc caattccatt tacaaagaat caagttaata ttgaaaatac
    11641 ggatgattgt cttgatgcta ctattgataa cttgctaatt aatttatctc ctaatcaaat
    11701 attatttgga ggtaacatac caactaaagt ttgtaaattt tgcgagcaac actctattca
    11761 gatttatgat tttatgaaaa tgaatgatgt tgctatttta aatgcagttg ctacagctga
    11821 aggggctata gcagaagcta ttaaaagaag tataatcaat atacatcaaa gtaactgttt
    11881 agtattaggt tatggaagat gtgcacaaat acttgcaaaa aaattatacg ctttggatgc
    11941 aaatgtatgt gttggcgcaa gaaataatga tgcaagaagt acggctaatg catttggata
    12001 ttccagtatt tctttaagtc aacttgatga aaaactttta caatttgatt atatttttaa
    12061 caccatacca gagtgtattt taacgaaaga aaggttagaa aaagtatcac aagaagtaac
    12121 tattatagat atagcttctt ctcctggagg agtagattat tctgttgtta aagaagcagg
    12181 gattaatgcg actctttgcc ttgggcttcc tggtaaatat tcaccaaaga catctggtga
    12241 aattcttgtt aacgctatag aaaatattat aaatgaaaga agggattaga aatgagactt
    12301 gaaggactta caattggagt aggatttact ggttcgtttt gtacttatga taaaatattt
    12361 atagagttag agaatttggt taaagaagga gctaatgtac acactatatt ttcagatgta
    12421 tcacaaaata tcgattgtag atttggaaat tctgaagagt ttatgaaaaa agcatatgaa
    12481 cttacaggaa ataaacctat agttacgatt gaagaggcag agccatttgg acctaaagga
    12541 attgctgata ttataataat agctccttgt actggaaata ctgctgcaaa attagcaaat
    12601 ggtattacag attcaccagt attaatggca gcaaaaggtc atcttcgtaa tgataaacca
    12661 ctagtaatat caatatcaac gaatgatgct ctaagcttta atttcaaaaa tattggcatt
    12721 ctccttaatt ctaaaaatat atattttgta ccttttggtc aagataattg caaagcaaag
    12781 cctaattcta tgattgcaca tactgagcta ataattccaa ctatagaact tgctctagag
    12841 aacaaacagc tacagcctgt tataaaaagt ccacatcaat agaattggtt cttataatat
    12901 tatgtattag atacaatact agcaaagagg ctgtctcaaa atagagagaa gcctcttttt
    12961 cttgttgaaa tgatgaaaat atatttaatt tcatacaaaa aaatgcctca tggactaaaa
    13021 agtctatttt gagctaatct ccgtaatttt tgctatatta aaattattta cttaatccaa
    13081 tttttaaatt agaatttata tcgttttgac tcttcaaata tcaatctaac tgttgttgat
    13141 acaaaagaag aggacataat taaaacaaat actgatagtc ctctaataaa caaattatct
    13201 acataataag ttactattcc aatacctcca atcgttaaaa ttacacttat aatcaaagaa
    13261 aaaacgctaa ttgtttttaa tttttccatg ctt
//
LOCUS       DAGQVA010000100        13272 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.100, whole genome shotgun sequence.
ACCESSION   DAGQVA010000100 DAGQVA010000000
VERSION     DAGQVA010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13272
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.100"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..264
                     /locus_tag="MIV85_003325"
     CDS             <1..264
                     /locus_tag="MIV85_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBY2962644.1"
                     /translation="KVPSNLMKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQF
                     SKLDEPTAVTEGKYFYFEESFEDVFILNKKADAIQFVVEGAGA"
     gene            264..497
                     /locus_tag="MIV85_003326"
     CDS             264..497
                     /locus_tag="MIV85_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962645.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKVVRYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            507..908
                     /locus_tag="MIV85_003327"
     CDS             507..908
                     /locus_tag="MIV85_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962646.1"
                     /translation="MGNNIIDDIEKRLESFGYILKDGDKWLIDFVREKIENIIKLDCN
                     IKTMPIELKEIEADMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTAYGKNKILTFRCLRW"
     gene            902..1249
                     /locus_tag="MIV85_003328"
     CDS             902..1249
                     /locus_tag="MIV85_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962647.1"
                     /translation="MVSKTRKAIEMLYRYKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            1249..1674
                     /locus_tag="MIV85_003329"
     CDS             1249..1674
                     /locus_tag="MIV85_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBY2962648.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            1667..2104
                     /locus_tag="MIV85_003330"
     CDS             1667..2104
                     /locus_tag="MIV85_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962649.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEINGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNNADKMNTVELFGGLKRGDNFE"
     gene            2097..2273
                     /locus_tag="MIV85_003331"
     CDS             2097..2273
                     /locus_tag="MIV85_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962650.1"
                     /translation="MSKTLSKGTDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEDRINKFMKGVS"
     gene            2274..3584
                     /locus_tag="MIV85_003332"
     CDS             2274..3584
                     /locus_tag="MIV85_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBY2962651.1"
                     /translation="MALGGGTFVTQNKVLPGSYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATARCSGIRGNDLKVIVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITELQDNDYV
                     TWKKEATLEATAGLTFTNGTNGEAVTGTEYQAFLDKIESYSFNALGCLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKIKDTGLLESSLIYWTTGAIAGC
                     DINKSNTNKRYDGEFDVDVNYTQIHLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     EKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            3606..4076
                     /locus_tag="MIV85_003333"
     CDS             3606..4076
                     /locus_tag="MIV85_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBY2962652.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            4129..4386
                     /locus_tag="MIV85_003334"
     CDS             4129..4386
                     /locus_tag="MIV85_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962653.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            4391..4831
                     /locus_tag="MIV85_003335"
     CDS             4391..4831
                     /locus_tag="MIV85_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBY2962654.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPVLNKKGKATGQYTSETDFNTYTLKLCVETVVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            5152..5313
                     /locus_tag="MIV85_003336"
     CDS             5152..5313
                     /locus_tag="MIV85_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962655.1"
                     /translation="MDNFLLSILASLIASLIGYIVCRCIKNVKSHSTRGKSKSGWELG
                     FKIKFRKFK"
     gene            5462..5695
                     /locus_tag="MIV85_003337"
     CDS             5462..5695
                     /locus_tag="MIV85_003337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962656.1"
                     /translation="MNKDIELTEKDLYCIARHIQVYVFKKDDEVIKKEDNPCCRCKHK
                     FKYYENSVCIYHCSVFQKLSKITGLKMGFGVKL"
     gene            5755..6282
                     /locus_tag="MIV85_003338"
     CDS             5755..6282
                     /locus_tag="MIV85_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBY2962657.1"
                     /translation="MREGKRRRGCLFWFIIIIIFSGVVGAIAGNSTNNGSTEKQKEDL
                     TKYIGEEGNIGDLKLTVNSISKASEIPVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDNSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            6425..6985
                     /locus_tag="MIV85_003339"
     CDS             6425..6985
                     /locus_tag="MIV85_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBY2962658.1"
                     /translation="MFCSNCGAEITGIGKFCSSCGVAVETEIIEDNNIKSNDLIVDAN
                     GIEINMTEIYRKYRKEKVNAIKNVMEISGLNIKEAKKIVDFSFEELKINFIDDTMSNS
                     EKEKIIQNQNRKNNIEKAQQESVACCPKCGSTSLTAQKKGFGIGKAMVGASLTGGIGL
                     VAGNLGAKKVRVTCLNCGKQFWAGKK"
     gene            7063..9351
                     /locus_tag="MIV85_003340"
     CDS             7063..9351
                     /locus_tag="MIV85_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBY2962659.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMTTAMNIVLSSFEQLQRTSSNAVN
                     ANSIIRAREELARAEAGFDRLERQIRESDNQQRKLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLGMINDGQQSDAGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTFSQIWTSIKNNAIMIFGVIQKKIEQSMSSKGFRTFIDNFINSLYVLGNVAYNI
                     FNEIISILGSPFFQAFVNAIIVGVSLIVQALGWIITQALNIANVFAQNWSIIAPIVLG
                     VAAAMLVYNNALLLSIANKVKDIALSAKSLVMSFAHIVAESYRAAALVATTIAQDGLN
                     AAMAACPITWILYGIIAIVVAFFVAIAIFNHFAGTSVSAIGVVAGAISVAASFIGNLF
                     IATGNLIIDIVALIYNTLAGFAEFFANFLDDPIGSVIRAVSGMANAVLGIIRSIASAF
                     DTVFGSNLADAVSGWQDKLQGWTDKVAGEAKIKVERMDPNKLHFDRFNYGKAWDAGYK
                     WGDKLETNIKDKFDISKMAEDAKKKLGLDDLWDKKYGLGDGFGSAGLNSPLNDAAKGA
                     KDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVNIKIDMNNTNNISKDNDLD
                     GIVNVLTEKLNDAMAVSAEGIV"
     gene            9368..10069
                     /locus_tag="MIV85_003341"
     CDS             9368..10069
                     /locus_tag="MIV85_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBY2962660.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINVGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPPPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWAICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     LSKYTIYKGQVLRLV"
     gene            10062..12032
                     /locus_tag="MIV85_003342"
     CDS             10062..12032
                     /locus_tag="MIV85_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBY2962661.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFKLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLSLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKNEKQNGPAQSTTSKEDTDMANKINKLLKGKLSNTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDLTYQVQNNNSNTSTNNNNKVSKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFK
                     RGAGINLKRVSADQSKDSRGKLLCNINDVKAGDLVFFAYNKGKGNVHHVGLYIGNDQY
                     IHAPQTGDVVKISSLSGRQKKKHDFARARRFF"
     gene            12046..12306
                     /locus_tag="MIV85_003343"
     CDS             12046..12306
                     /locus_tag="MIV85_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBY2962662.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMQIAFGTIESVNPLIVKIEQKA
                     SFEEFFLIQTETFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            12311..12730
                     /locus_tag="MIV85_003344"
     CDS             12311..12730
                     /locus_tag="MIV85_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBY2962663.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            12743..>13272
                     /locus_tag="MIV85_003345"
     CDS             12743..>13272
                     /locus_tag="MIV85_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBY2962664.1"
                     /translation="MTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTETYIAM
                     DELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPIDSRFNLGEYNYV
                     AIERISEGIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESEDSLRQ
                     RYYDSLNSQSFGGNMQ"
BASE COUNT         5274 a         1446 c         2637 g         3915 t
ORIGIN      
        1 aaagtaccat ctaatctaat gaaaactgca tatgatttta caactggatg gaaagtagga
       61 gcaggagcta aacaaatctt tatgtcctta gttcacccaa gtgcaataat tacacctgtt
      121 tcttatcagt tctctaagtt agacgaacca acagcagtta cagagggaaa atacttctac
      181 tttgaagaaa gttttgagga tgtatttata ttaaataaaa aagctgatgc aatacaattt
      241 gttgttgaag gagctggagc ataatggcac aagtaaggaa attaaataga atattaacca
      301 tagaagagtg taaaatagat gatttcttag agatgggata tgatttgata gatgaaactg
      361 gtaaggtagt aaggtatggc aagtcattaa atgtaaaaga tttaatagct gaaaataata
      421 ttttaaggtc aaaagttgag tctttagaag aagaaaataa gcagcttaaa gagaaaaata
      481 aacttactaa aaagtaggtg aaaattatgg gaaataatat aattgatgat atagaaaaaa
      541 gacttgaaag ttttggatat atattaaaag atggggataa gtggttaata gattttgtaa
      601 gagaaaaaat agaaaatatt attaaactag attgtaatat aaaaactatg ccaattgaat
      661 tgaaagaaat tgaagctgat atgatagttg gagagttctt atttaccaag aaaaatatgg
      721 ggcaattaga tatagaaagc attaactttg aagctgtaga aaagtctata tcagaaggtg
      781 atacaaaggt agatttcgct ataggaagtg gctctcaaac accagaacaa cgctttgata
      841 gcttaatagc ttatcttact gcttatggta agaataagat attaaccttt aggtgcttaa
      901 gatggtaagt aaaactagaa aagcaataga aatgttatat agatataaat gtactatagt
      961 tgagtatcag ccaatcaaag accctgtaac aaaacgaact aacaataaag aagtgattgt
     1021 attagaaaat caaccatgca agctttcata taaaaatata gtttctgcta cagaaggaaa
     1081 attagctaag ctagagcaaa ctattaaact ctttatatct ccagatatag aaattaaagc
     1141 aggttcaaaa cttattataa atgataaaga gtatgtaaga agtggagaat cagctatata
     1201 tccaaatcat caagaaataa tacttgagtt atttaaggat aaagcataat ggctagatgg
     1261 ggcagtgttg attttagaga gtttaaaaga gtttgtaaaa agatggagaa gcttacaaag
     1321 attgatttag ataagttttg caaagatgca gcaagagaat tagcagcaag actcttagga
     1381 aaagtaatta gaaggacacc agttgataca ggattcttaa gacaaggatg gaatggagtg
     1441 gcttatgcta ggtcgcttcc tgtgtataaa caaggaaata attatattat agaggttgtt
     1501 aatccgactg aatatgcaag ttatgtaaat ttcgggcata gaactaaaga cggaaaaggt
     1561 tgggttaaag gacaacattt cttaacaatt tcagagatgg aactacaaag ccaagttgat
     1621 aagattatag agaaaaagtt attaatatta cttaaaggag tatttgatgc ttaataatat
     1681 tatagatgga atatcagtaa agttagataa atcatttgga gaaaaatata caatttatag
     1741 tgaggatgta gagcaaggta ttaatgaacc ttgttttttt attgttcctt taaatccaag
     1801 caagacacca tatccaagcg ggagagaatt aaagaaaaat tcttttgatg tacattattt
     1861 ccctcgttca gaagctaaga attttgaaat aaatgagata gctgagatgt tactggaaga
     1921 attagagtat atagaaatca atggagattt agttagaggc acaaatatga attttgaaat
     1981 tatagacaat gttcttcact tctttgttga ttataactac ttcactataa agagtaataa
     2041 tgcagataaa atgaatacag tagagttatt cggtggtttg aagagaggtg ataattttga
     2101 gtaagacatt aagcaaagga accgattaca agtttactaa ggagcagata gttaattcta
     2161 agaagtatgt aaatagaaaa gacttattaa atgcaatttt aaaagaaaat gagttatatt
     2221 ccttctcaga agtagaggat agaataaata aattcatgaa aggagtgagt tagatggctt
     2281 taggtggagg aacatttgta acacagaata aagtattacc aggtagctat ataaactttg
     2341 taagtgccac aagggcaacc agttcactta gcgatagagg tattgttgca atgcctttag
     2401 aacttgattg gggaattgat gaagaagtat ttcaagtgac tagtgatgat tttgagaagt
     2461 attcaactaa gtattttgga tatgattata cacatgagaa gttgaaaggt ttgagagatt
     2521 tatttaaaaa tataaggcta ggatatttct ataaattaaa taaaggtgtt aaagctagtt
     2581 gtagtattgc tacagctaga tgcagtggta taagaggtaa tgacttaaaa gttatagtaa
     2641 caacaaatat agatgataat gctaaatttg atgttgtaac acttttagat aataagaaag
     2701 ttgatactca aatagctaaa gttattacag aactgcaaga taatgattat gtcacttgga
     2761 agaaggaagc aacattagag gctacagcag gattaacttt tactaatgga actaatggtg
     2821 aagctgtgac aggaacagag tatcaagctt ttcttgataa gatagaaagt tactcattta
     2881 atgcactagg atgtttggct acaacagcag agattaaaag tttgtttgta gagtttacta
     2941 agagaatgag agacaaagtt ggggctaagt ttcaaactgt attatataaa aagaatgatg
     3001 cagattatga aggtgtagta tctgttgaaa ataagattaa agatactgga ttattagaat
     3061 ctagcttaat ttactggact actggagcta tagcaggatg cgatataaat aaatctaata
     3121 ctaacaagcg atatgatggt gaatttgatg tagatgttaa ttacactcaa atacatttag
     3181 aagaagcttt aaaaactggt aagtttatat ttcataaggt tggagatgaa gttcatgtat
     3241 tagaggatat aaatactttt gttagtttta cagatgaaaa gaatgacgac ttttcaagta
     3301 atcaaagtgt tagagtactt gaccagattg ctaatgatat agcgacttta tttaatacaa
     3361 agtacttggg tgaagtacca aatgataaat ctggtcgtat ctcgttttgg aatgatgtag
     3421 ttaagcatca tgaacaactg caaaatatga gagcaataga agatttcaaa gctgatgatg
     3481 tttctgtaga acctggaagc gacaagaaga ctgttgtagt aagtgatgct gtaaaagtta
     3541 ttagtgctat gagtaagctt tatatgactg tttcagttag ttaacaataa gaaaggagaa
     3601 taataatggc acaacaaata aaagcaagag atacaataag tgcatctaag gcagagtgtt
     3661 ttgtaactat aaaaggtaaa agatataatt ttatgcaagc tattaactta gaagctaaaa
     3721 tggaaaagaa taagagtgag atacctatat taggtagtac tacaaaagga aataaatcaa
     3781 caggaagtaa atattcagga aatgcaacat tttattataa tacctctata tttagagaat
     3841 tgttgtatga gtataaagaa actggtgagg atatttactt cgatatacaa attaccaatg
     3901 aagacccaac aagttcagtg ggtcgtcaaa ctataatact ggaagattgc aatatggact
     3961 caggcataat tgctaaattt gatgctgatg gggagtattt agatgaagat atggatttta
     4021 cttttgagaa ttggaaatta gttgagaaat ttaatatagc aaatggtatg gagtaaaata
     4081 cacatttatg atttatgtat gtgtattttt tatttataag aataggagat gattaaaatt
     4141 aaggataaat atgagataaa agattcaatt tcttttgatt atagcaataa aagacctttg
     4201 gaagaacgtg tcagcgagat gtataaaaag gcaggaaaat atcttataga tatttcagat
     4261 aagttagcaa cagatacaat tgatggttcg tcattaaagc caataatcat aaaatttgaa
     4321 ataaatgaag ctggtgttgc aacaatagaa aaacaaacaa aatatttggt gatggaggta
     4381 gaataagaat atgggagatt taaacgcttt tttaagtcaa aatgcaataa aagtagagaa
     4441 tagaaagtat gtggcaagtg aaaggtttat aggagaagat ggaaaagcaa tcgaatggga
     4501 acttaaagca atagattcag atagagatag acaattaaga aaagattcaa ctataagagt
     4561 acctgtacta aataaaaaag ggaaagcaac agggcaatac actagtgaaa cagattttaa
     4621 tacttatact ttgaaactgt gtgtagaaac tgtagtattt ccagatttac atgatgcaga
     4681 acttcaaaat agctatggtg taatgggagc agaggaacta ttaacaacaa tgttaactcc
     4741 tggtgaatac acagaccttt caagtgaggt aggagaagtg aatggttttg ataggacttt
     4801 tgaagataaa gtagaagaag caaaaaacta attgaaggag gcgattatga tgctagtgta
     4861 gctcattatt gccttcataa attcaaatgg aaaccacatg aatatacaga tttaccagac
     4921 ttcgagaggg catttgttgc tgcttctata gatattaaag tagaagaaga aataaaagaa
     4981 gaaaaaaaga ttgctaaaga agctagaaga agtagaagaa gataaaatat aggtaaaata
     5041 tgtaagaatt atatgttata ataattgtag caagaagatg taatctacaa tttatagagt
     5101 ggagttcata ctgggataaa acctacttcc taatgaaagg aggtgggaag tatggacaat
     5161 tttttactta gtatattagc tagcttgata gctagtttaa ttggatatat cgtttgtaga
     5221 tgtatcaaaa acgtaaaaag ccactctact cgtggcaaga gtaaaagtgg ctgggaactt
     5281 ggttttaaaa taaagttccg caaatttaaa taatttatat tttttaaaat tatgaacttc
     5341 actctaccgc taaatagatt gtagttcttc ttgcctttat tataccacaa attagaaaaa
     5401 atatgcaaag tacttgtttt aatagtaagt acttttttta tgtgaaaaag aaggtgattg
     5461 aatgaataaa gatatagaac ttacagaaaa agatttatat tgtattgcta gacatattca
     5521 agtgtatgtg tttaaaaaag atgatgaggt cataaaaaag gaagataatc catgttgcag
     5581 atgcaagcat aaatttaagt attatgagaa tagtgtatgt atctatcatt gttcagtatt
     5641 tcagaagtta tctaaaatta caggtcttaa aatgggtttt ggagtcaaac tataatgtaa
     5701 aaattttgaa tatatagtat aatattctta taaaatataa tttaggggga tattatgaga
     5761 gaaggaaaga gaagaagagg atgtctattt tggtttatca ttattattat attttctggg
     5821 gttgttggag caatagcagg gaacagtact aataatggaa gcactgaaaa acaaaaagaa
     5881 gatttaacta aatatattgg tgaagaaggt aatataggag atttaaaatt aactgttaat
     5941 agtatttcaa aagctagtga aataccagta gcttctggtt atttggcgta cactccagat
     6001 agtggcaaat atggtattat aaatttaaca ataaaaaatc aaactaagga aagccaatct
     6061 tttatgctaa attcattcac attaatagga ccagataatt caaaatatgt tccatcttta
     6121 ttgattgatg taggaaataa atatataact atggatactg taaatcctaa tttagatgta
     6181 acaggtaata ttgcatttga aattcctaag gatttactag tttctgattg taaactaaaa
     6241 tatagtggtt cagagcaaga atttatatta aaagaaaaat aatatataga tttaaaatca
     6301 aaaatactaa aaacacttac taatgtaggt gtttttttaa tgaaaggatg tgatgataat
     6361 gtaaaaattt tactaatata gtataatatt cttataaaat tattatactg gggggggaaa
     6421 tgttatgttt tgttcaaatt gtggtgcaga aatcacaggc ataggcaagt tttgttcaag
     6481 ttgtggggtt gctgtagaaa ctgaaattat tgaagataat aatattaaat caaatgactt
     6541 aatcgttgat gctaatggaa tagaaataaa tatgactgaa atttatagaa aatatagaaa
     6601 agaaaaagta aacgcaataa aaaatgtaat ggaaataagt ggtttgaata taaaggaagc
     6661 aaaaaaaata gtggattttt cttttgaaga attaaaaatt aattttattg atgatactat
     6721 gagtaattca gaaaaggaaa aaataataca aaatcaaaat agaaaaaata atattgaaaa
     6781 agctcaacaa gaatcagttg cttgttgccc taagtgtggt tcaacatcct tgacagctca
     6841 aaaaaaaggt tttggtatag ggaaagcaat ggtaggagct agtctaactg gtggtatagg
     6901 tttagtagct ggaaatttag gagcaaagaa agttagagtt acatgcttga attgtgggaa
     6961 gcagttttgg gcaggcaaaa aatagatgta ttaattataa aaacacttac taatttagta
     7021 agtgttttta ttatctaaat taacagaaag gagagtgaaa aaatggctac aatacagaca
     7081 tcaattcgca tatttgatgg aatgacacct gcgtttcggc atatgacaac tgctatgaac
     7141 atagtactga gttcatttga gcaattacaa agaacttcta gtaatgcagt aaatgctaat
     7201 agcataataa gagctagaga agaactagca agagcagaag ctggatttga tagattagaa
     7261 cgacaaataa gagaatcaga taatcaacag cgaaaactta atgaggatat aaataagggt
     7321 gcaagttcta cagatagatt agttggaagt gcaaagaagc tagcagcaac ttatttaggt
     7381 ataagaacat taggaggtct aggaaattta agcgaccaga tgacaagtac taatgcgaga
     7441 cttggcatga taaatgatgg gcaacaatca gatgctggac ttaataaaat gatatttcaa
     7501 tcagctgaaa ggtcaagagc atcttactta gatactgcac aaatagtgag tcgtataggc
     7561 atgaacgcag gaaaggcgtt tagcagtaca aaagaaattg taggttttgc agagcaatta
     7621 aacaaaaaat ttgtaatagc aggcgcaagt actgaggaaa tgaactcggc attgttacag
     7681 ctaacccaag ggttgagttc tggcgtatta agaggtgagg aactgaatgc tgtgtttgag
     7741 tcagcaccta acatcatcca atcgattgca gattatttgg acgtggacat aggaaaaata
     7801 agaggaatgg catcagaggg aatgttaaca gcagatattg taaaaaactc attacttgca
     7861 gcagcagagc agaccaatgc agagtttgaa aaaatgcctt acacattttc tcaaatttgg
     7921 acttcaatta aaaataatgc aatcatgata tttggtgtta tacagaaaaa aattgaacag
     7981 tctatgtcta gtaagggatt tcgaaccttt atagataatt ttataaactc tttgtatgta
     8041 cttggaaatg ttgcttataa catttttaat gaaattataa gtatattagg gagcccgttt
     8101 tttcaagcat ttgtaaatgc gattattgta ggtgttagtt taatagtgca ggcactaggt
     8161 tggataataa cacaggcatt aaatattgct aatgtgtttg ctcagaactg gagtattatt
     8221 gcaccaatag tacttggagt tgcggctgct atgttagtgt ataacaatgc gttattactt
     8281 agtattgcga ataaagttaa agatattgca ctatctgcca aatctttagt catgagcttt
     8341 gcacatatag tagcagagtc ttatagagca gcagctttag tagcaactac aatagcacaa
     8401 gacggattaa atgcagcaat ggcagcttgt cctattactt ggattttata tggaattata
     8461 gctatagttg ttgcattttt tgtagctata gcaatattta atcacttcgc aggcactagt
     8521 gtatctgcta taggtgtagt tgcaggtgca atatcagttg cagcctcttt cataggaaac
     8581 ttatttattg caacaggaaa tttaattata gatattgtag ctttaatata caatacttta
     8641 gcaggctttg cagagttctt tgctaatttt ttagacgacc caattggctc tgttataaga
     8701 gcagtatccg gaatggctaa tgctgtatta ggcattataa gaagtatcgc aagtgcattt
     8761 gataccgtgt ttggttcaaa cttggcagat gcagtaagtg gatggcaaga taaattgcaa
     8821 ggttggactg ataaagtagc aggagaagct aaaataaaag tcgaaagaat ggaccctaat
     8881 aaactgcatt ttgacagatt taattatgga aaagcatggg acgcaggata taaatgggga
     8941 gataagttag aaactaatat aaaagataaa tttgatatta gcaaaatggc agaagatgca
     9001 aagaaaaaat taggattgga tgatttatgg gataaaaaat atggattagg agatggattt
     9061 ggttcagcag gattaaactc tcctctcaat gatgcagcaa aaggagcaaa agacactgcg
     9121 ggaaatacag caaagatggc taaaacaatg gataaaagcc aagaagactt aaaatactta
     9181 agagacatag cagaacagga aacaatcaat agatttacag gagtaaacat aaaaattgat
     9241 atgaacaaca caaacaacat aagtaaagat aatgacttag atggaatagt taatgttcta
     9301 actgaaaagt taaatgatgc aatggctgtt tcagccgaag gaatagttta ggaaggagag
     9361 tgagaaaatg gcttatgatt tttacctaga tggagtacaa ctaccaatcg caccaccaaa
     9421 gcttgaagtc aaagtgacaa ataaaaacaa gacagttgat ttaataaatg ttggagaagt
     9481 aaatatatta aaaaaagaag gattatctga aataagtttt gaagcagaat ttacacataa
     9541 taaactacca ttttatcgtg gaacttttag ggatgttcaa ttctttttaa gtaaactgga
     9601 actactaaaa actgattgta agccatttca atttattgta tcgagggaat taggtaataa
     9661 agtactattt aacactaata taaaagtatc tcttgaagag tatgctattt cagaagatgc
     9721 agataatggc tcagatacaa aagttgcaat aaaattaaaa caatatagag attactcaac
     9781 taaaaagtta gttcctgcaa ctcctgaaaa gacaaactat ggtaggactc cccctccagt
     9841 catgaaacca aaagaattta gaccagattc atccaataag ccaaatggta aaacatatac
     9901 agtaaaagca ggggattctc tttgggcaat ttgtcaaaag caattaggaa atggttcgtt
     9961 atacaagaaa gtatatgagt taaataaaac aatgatggat aaagctaaca agggaaaaaa
    10021 attaagtaaa tacaccatct ataaagggca ggtgttgagg cttgtctgat gatttagttc
    10081 tggcgaatga tagagatata aggctagtta ttgcacattg ggaagatttc tacgaacctg
    10141 tagttttgga tggtatcaca tgggaaatag agagacgagg aacaccatct aaacttgaat
    10201 ttacaatagt catggatgat atattagagt tttgtgaagg taactctgta agactatatt
    10261 acaaaggtgt aggtatattc tatggatata tatttcagaa aaagagagat aaagaaaatc
    10321 atatcaagat agttgcttat gaccagctaa gatattttaa gaataaagat acttatgtat
    10381 atagtaataa aacagcaagt gaacttgtaa agatgttggc taaggatttt aaattaaaat
    10441 acaatgtcat agaagataca aaatataaaa tatcgagagt tgaagaaaat aaaacactct
    10501 ttgatatggt cttaactgca ctagatgata ctctaagaga gaaaaaggaa atgtatgttt
    10561 tatatgatga ttttggaaga ataacattaa agaatgttgc ttctatgaaa cttgatacgg
    10621 ttatgaacaa tgatgtaatt gaggactttg actacaattc ttctattgat agtgatactt
    10681 acacaaagat taaacttgtg agagataatg aagaaacagg aaaaagagat gtgtatattg
    10741 ctcaagactc aacgcatatg aggagttggg gaatactaca actatttgat acagttgata
    10801 aaaatatgag tgaagcagag ataaaacaaa aatgtgatat actcctaaaa ctatataata
    10861 agaaaactaa gtcattaagt ttaaaaaatg tgttaggaga tattagagta agagcaggtt
    10921 gtttagtacc tgtttttttg tcgttaggag atattgattt acaaaattat atgttagttg
    10981 agaaagtaaa acatacattt gaaaataaca gtcattttat ggacctaact ttggttgatg
    11041 gagacgaatt tgcttcttat tcttcatcaa gttatagtag tggaaatact aataataaaa
    11101 atgagaaaca aaatggtcct gcacaaagta ctacaagtaa agaagatact gatatggcta
    11161 ataagattaa taaactactt aaaggtaaat tatcaaatac aggaaatata tttgttaaat
    11221 attcaaatgc ttataaagtt aatccagcac tcatggctgc tatatctatg cacgaatcag
    11281 ctagagggac ttcaaatatt gcaaatacta aaaataattt ctttggaatg aaaaaaaatg
    11341 gagattacat gagtttttct agtgtagacg aaggaataaa aagaggtata agtaatttat
    11401 caagaaacta tatccatata ggacgaaaaa ctttagaaag catcagaaat aaatattctt
    11461 ctagttcaga caaagaatgg gtaaaatgtg taggtgcatt ttataagcaa ataacaggaa
    11521 gtacttataa ttctaatagt gcaggcacag gagttggaag taatgaagaa gcagaaaaga
    11581 atttaaaaga tttaacttat caagttcaaa acaataattc taatacatca acaaacaata
    11641 ataataaagt aagtaaagtt attcaagaag caaaaaatca acttggcaag ccttacaaat
    11701 ggggtggtaa tggtccaaag agttttgact gtagtggtct tatggtgtgg gcatttaaaa
    11761 gaggtgcagg aataaatctc aaaagagttt cagcagacca atcaaaagat agtagaggaa
    11821 aactattatg taacataaat gatgtaaaag ctggtgattt agtattcttt gcatacaaca
    11881 aaggaaaagg aaatgtacat catgttggac tatatatagg aaatgaccaa tatattcatg
    11941 ctccacaaac tggtgacgta gtaaaaataa gtagtttaag tggtagacaa aagaaaaagc
    12001 atgattttgc aagagctaga agattctttt aagtgaggtg ataaagtgtc acaagaatta
    12061 ttgcaaataa ttaagaaggc tgcaatggat gcagtagaaa caagcaatcc aatgcaaatt
    12121 gcatttggaa ctatagaaag tgttaatcct ttgatagtta agatagaaca aaaagcatct
    12181 tttgaagaat tttttctaat acaaacagag acttttaaaa gatatacaga taaaaaaata
    12241 ggggataaat tagtcttaat taggatgcaa ggaggacagc aatatttgat tttagatagg
    12301 atgtgatgaa atgttaccaa cagataacat tgactatgat atagaagatg tatcgataat
    12361 taattttgat gttagacaag aaccaagtaa gacgtttaaa ttgaatatag agaaaaatag
    12421 agtagatggt atttgtgatg atgtagaagc attaaaacaa accatttttt taattttaaa
    12481 tactgaaagg tatgagcacc ttatttattc tagaaattat ggtgttgaat taaatgattt
    12541 aattggagaa cctatttcat atgtaatacc cgaacttgaa agaaggataa cagaagcact
    12601 aattcaagat gataggattg aaaatataga taattttgag tttcaaaata taaagggtaa
    12661 agtacaatgt agattttcag ttcatacaaa atatggaaat ataaaagcag agaaggtggt
    12721 gagtgtataa ttgtttgagt taatgacatt tgaaaatata attaaaagaa tgttagatag
    12781 tgtaccagat acttttgata aaagggaagg ttctataata tataatgctc ttgctcctgt
    12841 tgctatagaa cttacagaaa catacattgc tatggatgaa ttactagacc aaacattcgt
    12901 agatactgct agttattatt atttagagaa gagatgtaaa gagagaggta ttacaccact
    12961 tgaagccact aatacaattg caaaaggagt ttttaacata gatattccta ttgattctag
    13021 gtttaatcta ggagaatata actatgtagc aattgagaga atatctgaag gtatatataa
    13081 gatgaaatgt gagactgcgg gacctatttt tgagttggga caactaatac ctatcgaata
    13141 tatagacaaa ttagaaacag cagaactgac agaaatactg ataaatggag aagatgaaga
    13201 gagtgaggat agtttaagac aaagatatta tgatagccta aattcacaga gctttggtgg
    13261 aaatatgcaa aa
//
LOCUS       DAGQVA010000101        13072 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.101, whole genome shotgun sequence.
ACCESSION   DAGQVA010000101 DAGQVA010000000
VERSION     DAGQVA010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13072
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.101"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(4..816)
                     /locus_tag="MIV85_003346"
     CDS             complement(4..816)
                     /locus_tag="MIV85_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBY2962665.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            1238..2389
                     /locus_tag="MIV85_003347"
     CDS             1238..2389
                     /locus_tag="MIV85_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962666.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            2507..3145
                     /locus_tag="MIV85_003348"
     CDS             2507..3145
                     /locus_tag="MIV85_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBY2962667.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            3146..4168
                     /locus_tag="MIV85_003349"
     CDS             3146..4168
                     /locus_tag="MIV85_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBY2962668.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            4158..4778
                     /locus_tag="MIV85_003350"
     CDS             4158..4778
                     /locus_tag="MIV85_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962669.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKVGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(4902..5588)
                     /locus_tag="MIV85_003351"
     CDS             complement(4902..5588)
                     /locus_tag="MIV85_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBY2962670.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(5602..6147)
                     /locus_tag="MIV85_003352"
     CDS             complement(5602..6147)
                     /locus_tag="MIV85_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962671.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            6375..7622
                     /locus_tag="MIV85_003353"
     CDS             6375..7622
                     /locus_tag="MIV85_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBY2962672.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            7709..9703
                     /locus_tag="MIV85_003354"
     CDS             7709..9703
                     /locus_tag="MIV85_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBY2962673.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNYCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            9703..11025
                     /locus_tag="MIV85_003355"
     CDS             9703..11025
                     /locus_tag="MIV85_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBY2962674.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            11304..12590
                     /locus_tag="MIV85_003356"
     CDS             11304..12590
                     /locus_tag="MIV85_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBY2962675.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            12676..>13072
                     /locus_tag="MIV85_003357"
     CDS             12676..>13072
                     /locus_tag="MIV85_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006316653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBY2962676.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDL"
BASE COUNT         5198 a         1382 c         2202 g         4290 t
ORIGIN      
        1 tatttattta attttttcaa caacattagt caatattgaa tctaaatcat cactaatttc
       61 tgtaactcca ttatgagtaa tatctataat ttctttagtc ataggaagtt ctcctaaaag
      121 ctctaagtct aaatcatcta aaaacttttc agtagattct ccttcaaata acttgatttt
      181 tttagaacaa tcaggacatt ggatataact catattttca ataactccaa ggacatttat
      241 gttcattttt ttagccatat taacagcttt tgatacaatc atagatacca aatcttgagg
      301 tactgaaacc ataactattc cacttatagg aatagattgc ataactgtta aggcaacatc
      361 tccagtacca ggaggcatat ctattaataa atagtctaat tcttcccaaa gtacatcagt
      421 ataaaattgc tttacaaccc ctccaagtaa aggtcctctc caaacaacag gttcattttc
      481 atcatctatc ataaggttta tagacattac ttttatgtta tttgagtttt ctacagggta
      541 aatataagag ccatcagaat aagcttttac attttttaca cccataagtc taggaatact
      601 tggtccagtt atatctgagt ctaatatacc aaccttatat cccattttgt ttagcttatt
      661 agcaagtaaa gcagttacag ttgattttcc aactccaccc ttcccactca taacaccaat
      721 tatttttcca aatttattgt tagggttatt ttcaatagaa caatttgatt gactattaca
      781 atttcccttt gatggacatg aattacaatc tgccatatct attacctcca aactttaata
      841 tttattagat tatttgtaac ctacatatac tattttagta caattgaacc ataaagtcat
      901 tatttaaaag caacttagaa gattttctat tgatttattc atagactata gcaaaaagaa
      961 tacaataaaa aaattataac attcttgaaa aagtgattat ttcaatttag ttatagaact
     1021 tagtcatata aatatataga aaatatttta atatattata cataacgggt tattttataa
     1081 gtttaactat aaattaggtt tatattttat aaaaatttgc taaaaaaaac aattaaaaat
     1141 tgtaaagaaa aaagatataa ttagaactgt agtaataaat gttttattat agataataga
     1201 gttttaagta tcttaaataa tatttggagg aatatgaatg gaattaagac caagaagtgc
     1261 aaaattagaa gaatttgata aagtaataga attaataaac tatgtattta gaatatcaag
     1321 aaatcataaa ccaactatga tggaagaatt tcctctttta ctaagtaaaa ataatataga
     1381 aaatatgatt ataatatcag aagatgataa agtggtttct gatgtaaact atctaattca
     1441 ggatgtatct attcaaggaa acagattgaa ggttgcagct ataggtggag tatgtactca
     1501 tccagattat gaaaagagag gctattcatc taagatattg gataaagtag aagaaaaaat
     1561 gttttatgat ggtgtagata ttgtaattat atcaggaaca agaagtctat acagtagaag
     1621 aaattgtagt ttggtaaaga gtttttataa atatacaata aaacctgaag atgtaaaaat
     1681 agcatatgaa atagttgaat ttgatgaaac taattttgaa aaagataatg atttagataa
     1741 aatgattgaa ctatataatc aaaatagtac tagatttata agaacgagag atgagtttca
     1801 aaaactattg catgcagcaa ctattgcctg gggaccaatt ggttacaaga aggtatttat
     1861 aaaggaaaat aataatataa taggatattt gataataaga acaataaaaa aagaagattc
     1921 tactgtagga gaagttgctg aaatagggtt aaactctgta aatgttgaaa atatattgaa
     1981 atatgttgca aataaatttg gattagaatc tttaaattat aaagtacatg tgaaaaatct
     2041 taaagaccag ttgaaatgta atgggacaaa atctttggat tatcaacaag gaactatgaa
     2101 aataataaat tttactaagt tgtgtgatag tttaagaagt tattttagtc aatatgtaga
     2161 ttttgaatta ctaaaataca tggaatttaa acaagttgaa aataaatata ttattaaata
     2221 caaagaagaa gaacttgtaa tagaaaattt ggataagctt aataaactgt tttttgaaaa
     2281 aaatgaggaa cagtacaatg aatttaaaca tctaaaaaat atatatgaat ttgctacaaa
     2341 ggcatttcct gtagattttc catggactgc aaatttaaat tatcaatagt tttagatgat
     2401 attaaataaa attgattgat acctagagtt agtccttgtt aaataagaga aattattgga
     2461 tattgaaaaa gcaattttgt aagtaattag aaaggatgag tattatatgg acatacttga
     2521 tgatatagca gaatgtatat taaatatggg tgtagataat atagagaatt tagtaaaaat
     2581 tgctatagat aaaaatattg atgtggaaga tatttatgaa tatggtttaa acaaaggtat
     2641 gataggagct ttagataagt ttgagaataa ggaatactat ctttcagaag ttatagtatg
     2701 cacagatgca ttaaataaag gtattaatct tttgaaggga actggaaaag taaagaaaaa
     2761 atcaaaggga gtaattctga tgtctgtagt agaaggagat actcatgaga taggaaaaaa
     2821 tattgtaaaa gtaatggtag aagccactgg atataaggtt attgacttag gtgtaaatag
     2881 aaaaagtgaa gatataatag aagaagctat aaaaaacaat gtagatataa taggcttatc
     2941 ttcaatgatg acaactacaa tggaaaatat gaaatcggtt atagacgaac ttaatatgat
     3001 tgagatagat aaaagaccaa aagtaataat tggtggagga cctgtaagta tggagtttgc
     3061 agaagaaata ggagcagatg gatacagttc aaatgctcca aaagcagtta aattaataaa
     3121 taaacttata ggaggtgaag tttaaatgtt ttcagatatg actttacttc agtatataaa
     3181 tagtgaagat agaggttttt ttctgcctga tatgggtaca aatggattgt tcttaataaa
     3241 taaaaaggca tatgaagtat atgatagtgt agatttgcaa ttagaattag caaagactat
     3301 ggacaagtat tttgaatcag attttatata ctcattctgt gatgggatta cattttgtga
     3361 aactctgggt ttagatacat taagaccaga ttatgatttt ccaagtgtat tgacacatac
     3421 tataactgac agagataaat taagaaaatt agatgttcca gacccttata cgagtggacg
     3481 tatgccactc aatatagaga gcttatcagt tatatcaaaa agtattaaaa aaccactata
     3541 tgaatcgata caaggtccat ttacacttgc aggtcaatta gctggagcta ctcaactttt
     3601 aagatgtata ataactgata aaaaatttgt agaagaatta ttggaattta caactgaatt
     3661 ggtaagaaga tatgctgtag ctgcaaataa agcaggagca aaatatattt caatagcaga
     3721 gccaacatca gtaaccctaa gtaaagatag atttgatgaa tttatagtaa aaaatttaaa
     3781 taaaatctac aatgaacttg attgttggaa aggtatgcat atatgtggag acaccagaga
     3841 attattagat aatatgctaa gttgtaatat agatgcagta agtttagacc aaattttaga
     3901 ctatgaagaa attgctccaa tgattcctag agatatagtt ttgattggta atttagaccc
     3961 aataaaactt cttggacgtt ctaagccaga taagattaga agagagacac taaaattgtt
     4021 aaagaagatg agaagatatg ataacttttt atgtgatttt ggctgtaact gcttaaatac
     4081 cactccagta gaaaatttac aagcagctat aaaggcagga agaattagtt ataaagaatt
     4141 agataggatt gatattgatg aattataata gtaataaaaa taaatatctt ttaaaggata
     4201 taaatttaga tgatattttt atagataaga atattgtgct aaagtttttg gggtatggaa
     4261 atagaaaagc tccagataca attagtaaaa tcgttgaaag agaaataaga aatataaatg
     4321 atattttaga tatcaagata tatataagtg aagttgatat taataaaaca cctaaagaat
     4381 gtaaaaaagc atttgctgta ctatatacaa taggggataa aattgatttt aagatgaatg
     4441 actatatgga aaattgcaat atgatggcag ggctggcatt ggataaggta ggtatagtat
     4501 gtttagattg tattaatgag aaaataaaaa tgtatttaaa aggaaagtat gatagtctca
     4561 aaatatcgca tgaaatatat ccaggagata aagattttga agtagagaga caaaaggata
     4621 tttataacta tgtaaaaaat aaatataata gtatagaaat agaaattaat gattatcatc
     4681 aactatcccc cataaaaagt gttgcaatgc ttattttaat gggggatgaa gaaaatttag
     4741 aatcaagatg tagtaagtgt cctagaaaat gcttttagtt aattttcaag actaagattt
     4801 gttttgtgta taaattgcaa taattttttt ggtcatttta tgtataaact aaaaaaatta
     4861 ttgcaaagta atattctatt taatttgaac agacttacaa actatagtag tttctttaat
     4921 tcaataagtg tatttatttc ataagttggt atatgattag tataatttat actgttattg
     4981 gaatttaacc aacaagtatc tattcctgaa tttattccac ctaagatatc agaggttaag
     5041 ctatccccaa ttattaaggc agaagattta tcatgacaat taaacttttt gagagcgtat
     5101 ttaaatattt caggatttgg ttttgatatt ttcaactctt cagatacaac cattccatca
     5161 atatattctt ttatttttga attttcaagt cttttctttt gaactgcaga aattccattt
     5221 gttattataa caatagtata ctttttttta agatattgta atatatcgat tgcacctgga
     5281 attaaaaatg tacattcacc taaaaaattt aagtacattt tgctaagagt ttcagaatca
     5341 acatccaaag atattttatt tgcaaaaagt tcaaatctaa gtaatttaag ttcattcaaa
     5401 gttataatat ttttttcaag gtcgagccaa agcttatcac ttatatttct atatgactct
     5461 atataattct caaaattaaa ttctaaatca aactcagata gaagtttttt aaaagcatgt
     5521 gattcacttt tcttaaaatc aaataaagta tcatctgcat caaaaaatat aaatttatat
     5581 gtcttcatgg tttttactcc tttacaagat gactgcaaaa attactttac tttcactatt
     5641 tgagtcattt tgccatttat gttttgttcc taaaggaact tttacactat ctcctttgga
     5701 caaagtaaat tcatcatcat ccataaaaag tttaacttct ccctccaaaa catatgcaat
     5761 ttcatctcca ttatgagtaa tcctatcaac acaagaagaa gtgtttggag ctaaatccat
     5821 aattgcaaat tctaaattac cactagagtc tggaattaaa atctcatata taacttcttt
     5881 gcttccaggt aaaataactt tttttctatt atcatgtctt actatcaagt tttttttatc
     5941 tacctcagat acaaaaaatg taaataaagg aacgtttaga gaagaggcta tagattttaa
     6001 tgaatttaca gatggattag caagacctcg ttctatttgg ctcaataatg atggtgtaac
     6061 atcagctagt tttgctaaat ctcgaatact taagttttgt ttttttcgaa cttcagctat
     6121 tttttcccct aaatttaaat cattcatata aatatcctct ctttttaatt taaaaaatat
     6181 taacttaaaa taatcaagta aaatgattat gtagtatgaa attattataa catatagaat
     6241 taggttttga aaaaactatg ttcaatataa ttaaataaat taaaatataa ttgacaaagt
     6301 ggatacagaa tacttaaaat atatttaaat aaaattaagc aaaagatagt taatttatga
     6361 taggagggga tattatgcaa ataacgactt ttggagctat atttggttta ttaatagcaa
     6421 ttattttaat tataaaaaaa tttcaagctg tatatagttt aatgctagga gcatttattg
     6481 gaggattagt tggaggagca aatataacac aaactgtaga ttttatggca aatggagcta
     6541 tgaatatatc accatcaatt cttagagctt tggcatcagg tgtattagct ggaagtttaa
     6601 taaaaacagg ggcagtagat aaaatatcag aacagattgt aaaaatattt ggtgaaaaga
     6661 gggctttatt ttcgattgcc atttcaacta tggtacttgc tggagtaggc gtaaatttgg
     6721 atgtatctat aataactgta gcacctatag gattatatat aggtagaaaa ttaaattatt
     6781 ctaaattgtc aatactatta gctatgttgg gagggggtaa agcaggtaat ataatatcac
     6841 caaatccaaa tactatagca gtagcagata atttttctgt caatctctct agtgttatga
     6901 tggcaaatat aattccagca attattggag ttgttattac agttatttta gcaagtatat
     6961 taataaataa aggaaataaa gtacaatcat atgaaatttt agagcaaaga gaagatttac
     7021 caagtttatt taaatcatta tgtggtccaa ttatagctat atttctattg tttttaggaa
     7081 atgtatctcc tatagttata gacccaatga tagcccttcc aataggagga atcgtaactc
     7141 taattgtcac aggaaacttg aacaattcaa gagaatattt agcttttgga ttatctaaga
     7201 tgcaaggggt atgcatatta ttacttggaa cagggactat cgcaggaatt atacagatgt
     7261 ctgaattaca acagagtaca ataggtgctt tacaattttt aaatatgcca caatttttat
     7321 tggcaccagt ttcgggtata cttatgtcat tagcaacagc atcatcaaca gctggtgcta
     7381 ctatagcatc atctactttt catgatgcta taataaatgg tgggctatca ccgatttcag
     7441 gtgcctcaat agtaaatgct gggtctagtg tattcgagca attaccacat ggctcactat
     7501 ttcatactag tgcaggtagt ataaacatgg atataggtga aagatttaag ttaattccat
     7561 atgaagcatt gataggaata gtaatgacta taatttcaac atctattcaa ttagttttat
     7621 aataaatata aatatttaat gaaaaaagta ggattttgtt attaaatatt gaatttatta
     7681 tagtaaaaaa gaagattgga gttttaaagt gaataaaaaa aagattgtta ttatagggat
     7741 tatttattca tttttagtag tattttcact tacaaatatg tatgtaaata tggagtataa
     7801 tctaaatgta tttgaatata ttaagaagtc acttccattt acagaagaag aaaaaaagtg
     7861 gttagaaaaa cacaagaatt tgatttacag ctctgaccaa agttcacctc ctttgagata
     7921 taaaggtaag gaagatggac agtataaggg aattattgtt gatttaataa attctctgtc
     7981 aattcaaatt ggtagagatt tttattttaa accaaataat tggtggaaag aatctttcgt
     8041 aaattcaata gatgatagta taaagttttt tgacttgatt ccatcaaaag aaagggcaaa
     8101 taaatttata tttactgacc caatatacac tttgagtgca aatatattga aagataaaaa
     8161 gtcccaagat ataaatagtt acatggattt aaaggggaaa acagtagcaa ttccagaagg
     8221 tgattattct ataaattttt taaagcaaaa aattcaagat ataaacattt tgttgactcc
     8281 agatataaag actggagtca accatttaat gtctggaaaa gtagacgcag ttgttggtga
     8341 tgaaccagta ttgcgatact atataaataa ttatggactt tcaaataaat acagtgtttt
     8401 aagtaatcct atatatacta aaaaagcagt tcttgctgta cctaaacaat atgaagagct
     8461 ggttagtatt ttaaataaag gcatttttaa acttcagaaa aatggagtgt ataaagattt
     8521 aaagaaaaaa tggtattcta cgtataatga agttgatgat atattgtatg agcgaggaat
     8581 tgtgcctagt atttatcttt ttataggtat aattttaata tcaatttatg ttttttatag
     8641 ctatacatat ttgttaaaga tagaaatcaa aaggaaaaca gaacaggtaa tagaaaataa
     8701 aaaaacttta gaggcaactt ttaatagtat tacagatata ataatgcttg tagatgaaaa
     8761 taacaatata gtagaatcga acaaagtact atatgacttt atgggtgaaa tgagttataa
     8821 gatagcagat ttgattagca tgataaaagg tgttattgaa aataccttct ctgaaaatac
     8881 taataaaact agtgaaatag aaatacacaa taaaatttta aagataaaca cttttcctgt
     8941 agagtataaa aaaaataata ctgagtatat agtagttctt attaaagata taactaatga
     9001 taaaatagta gaggcgaaat tacttagaga aaacaaaatg atatctatag gacaattagc
     9061 ttctggggta gcacatgaga taagaaatcc tttgggtata ataagaaata attgctatct
     9121 cttaaaagat aacgttacaa tggaagaagt aaatgattgt gttaaatcaa tagaaagtaa
     9181 tgtagatagg gcaagtaata taataaccaa cttgttaaat ttcgcaagaa tatcagatga
     9241 taatttagaa catataaata taagaaattt tattgaaaat atagtgaaac ttcaatataa
     9301 aatgttacag ttaaagaatg ttgaaataaa aattgactgt gaacataatt tagtatgcta
     9361 tataaatgga gaatcgttaa aacatgtatt tataaattta atttctaatt caatagatgc
     9421 aatacatcaa gatggaaaaa ttattatata ctgttatgaa aaaaattatt gtttatttat
     9481 agattttaaa gataatggtg aaggaataaa agaagatgcc ctaaaggaca tatttaatcc
     9541 cttctataca acaaaaccaa ttggtgaggg aactggttta ggtttataca ttacttataa
     9601 tgagattaaa aagaataatg gagatataag tgttgaaagt aaattggggg ttggaacttg
     9661 ttttcatata aaaattccat taaataaaga ggtgactata taatgaaaat actattagtt
     9721 gatgatgagc tagaatatgg agtggtaatg aaaaaaattc tacaaaagaa gggctatctt
     9781 gtagatatag cactaagtgg tgaagaagct ataaatataa ttaaaaaaga taaaaattat
     9841 gatttggttt tgtctgatgt tatgatgaaa aatatggatg gagtacagct attagataga
     9901 attaaatcta ttaatagaga tatagaggtt atattagtta caggatatgg aagtattgaa
     9961 aatgcagttg atgctatgaa aagaggagct ttatcttatt ttataaaaag taatcccatt
    10021 gaaaatttat tagaagaagt tgaaaaggta aaggcaagta aaatatctgt ttctgtacaa
    10081 aaaaataatc tggaatttac tttggaatct aaaaatagag attttaataa tatcataaaa
    10141 atagcaaaaa aagctgcttg taaagatgtt aatatattaa tcttggggga atctggtgta
    10201 ggaaaagata tattagctag atatatacat agcataagtc caagaaagaa tgagatattt
    10261 gtacctgtaa attgttgttc tttttcagaa aatctattgg agtctgagtt gtttggtcat
    10321 gaaaaaggtt cttttacagg agcagtagat agtagaaaag gtagatttga actttcgaat
    10381 aaaggaactc tatttttgga tgaaatagga gatatacctc taaatgttca ggtaaaactt
    10441 ttgaggacac ttgaggacaa atctatagag aggataggaa gtaataaatc tattaaagtt
    10501 gactttaggt taatttgtgc tatgaataaa gaaccaaaag tggaaatatc aaatggaaat
    10561 ataagagaag atttttttta tagaataagt acaataacaa taactatacc accgctaaga
    10621 aagagaagag aagacttaac tactcttata gaatttttct taaataagta ccaaattgaa
    10681 catgataaaa agatacactc gattgataag gaagtaaagg attttttatt aaattacaat
    10741 tatccaggaa atataagaga attaaaaaat ataataaata gacttgtagt tttaagtgaa
    10801 gaaggcaatt tatcaaaaga caatttaaat ttaatatcaa ataatgtata catagatgat
    10861 aaaataagta ttagaccttt aagagaaata agaaaagagt ttgaatgtga gtatattgaa
    10921 aaagttttat ctttgtgtgg aaataatatt tcaaatacag ctaaaaaatt ggagattagt
    10981 agaagacagt taaccaataa aatatcagag tataatatta agtgagaaaa aaacttctca
    11041 ttaagtgaga aaaaaatttc tcaaactgta ttaaaagata aacagaaaaa atctgtttat
    11101 ctttttttat tataatttta aaaattaata tttacaataa ttattgctaa attcaatatt
    11161 ggtgtaaatt aaaaatgaaa atttctatga cattaataca tagaatatat attttaaata
    11221 attggcatag aaaatgcttt atatattaat aaacgtaata aatactttta attgcgatta
    11281 aatatattaa gggggatttt catatgaagc tagagctagg gaatatattt ataaaaaatg
    11341 ttgaatttgg agaaaagaca gaagtaaaag atggagtact atatattagt agcgaagaaa
    11401 tagaaaagat agtattagaa gatgaaagga ttgtaagtgt aaatgttgaa cttgcaagac
    11461 ctggcgaatc aataagaata gctccagtta aagatgtaat agagcctaga gttaaaattg
    11521 gagatgaaag caaaatattt cctggaatta taaataaagt gaagactgta ggaagtggaa
    11581 gaacccatgt acttttagga gcttgtgttg taacttgtgg aaatatagtt ggatttcaag
    11641 aaggcgtaat tgatatgagt ggtcctactg ctaaatatac acctttttca aaaacaaata
    11701 atatatgtat tgttataaaa gcaaaggatg gtatagatac tcatgattat gaagaagcag
    11761 ctagaattgc aggattaaaa ataggtgcat atgtaggtga ggcaggaaga gaagttgagc
    11821 cagatgaagt cattgtatat gagacaaagc cattattaaa acaagtaaaa gaatatccag
    11881 acctgccaac agtagcatat gttcacatgt tacaatcaca aggactttta catgacactt
    11941 attactatgg ggtggatgct aaacagatag tgcctacatt tatgtatcca actgaaataa
    12001 tggatggagc tataatatct ggaaactgtg tagcaccatg tgataaggtt acaacattcc
    12061 atcatttaaa taatccagtt atacatgact tatataaaag acatggaaaa gatttaaact
    12121 ttataggagt tattttgact aatgagaacg tattcttagt cgataaagag agaagctctg
    12181 atatggtagc taaattaata gaatttttag gagttgatgg agttctagtg acagaagaag
    12241 gttatgggaa tccagatact gacctaatga tgaattgtag aaaatgtagt gaagttggag
    12301 caaatgtagt tttgataacg gatgaatttc ctggaaaaga tggcaagagt caatctatag
    12361 cagacgctac taaggaagca gatgcagttg tttcttgtgg tcaaggaaat ctagtggttc
    12421 atttcccagc aatggaaaaa attataggaa ctttagatta tgttgaaatg atgataggtg
    12481 ggtataaagg atgcttaaat gaagacggaa gcatggatgc agagctacaa attataatag
    12541 catcaactat agcaaatggc tataatcatt tgacagcaag atattattaa ataagtattt
    12601 gaatataaag ttctgttgat ataatcattg gtctaattga tgtaacaact ataaagtgat
    12661 ttggaggatt aagagatgag taaaatcaga gtggttcatt atataaacaa tttctttgct
    12721 ggtataggtg gagaggaaaa agcagatatt ccgccagaaa aaagggctgg tgtagtagga
    12781 cctggaatag catttcagag tcaatttaat gatgatgcag agataatctc aactgtaatt
    12841 tgcggagata cgtattttgg tgaaaatatt gagagtgcaa ctcaagaact tttaaaaatg
    12901 ataaaagaag aaagccctga tttatttatt gcaggcccag catttaatgc aggtagatat
    12961 ggagtagctt gtgggactat ttgtaaggca gttgaagaag agttaaatat tcctgtaatt
    13021 acaggcatgt ataaagaaaa tccaggtgta gatatgttta aattagattt gc
//
LOCUS       DAGQVA010000102        12831 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.102, whole genome shotgun sequence.
ACCESSION   DAGQVA010000102 DAGQVA010000000
VERSION     DAGQVA010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12831
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.102"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            23..139
                     /gene="rrf"
                     /locus_tag="MIV85_003358"
     rRNA            23..139
                     /gene="rrf"
                     /locus_tag="MIV85_003358"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            147..221
                     /locus_tag="MIV85_003359"
     tRNA            147..221
                     /locus_tag="MIV85_003359"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:179..181,aa:Asn,seq:gtt)
     gene            227..312
                     /locus_tag="MIV85_003360"
     tRNA            227..312
                     /locus_tag="MIV85_003360"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:261..263,aa:Leu,seq:taa)
     gene            328..403
                     /locus_tag="MIV85_003361"
     tRNA            328..403
                     /locus_tag="MIV85_003361"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:361..363,aa:Met,seq:cat)
     gene            411..485
                     /locus_tag="MIV85_003362"
     tRNA            411..485
                     /locus_tag="MIV85_003362"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Glu,seq:ttc)
     gene            500..573
                     /locus_tag="MIV85_003363"
     tRNA            500..573
                     /locus_tag="MIV85_003363"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:532..534,aa:Gly,seq:tcc)
     gene            579..654
                     /locus_tag="MIV85_003364"
     tRNA            579..654
                     /locus_tag="MIV85_003364"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Val,seq:tac)
     gene            660..736
                     /locus_tag="MIV85_003365"
     tRNA            660..736
                     /locus_tag="MIV85_003365"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:694..696,aa:Asp,seq:gtc)
     gene            747..821
                     /locus_tag="MIV85_003366"
     tRNA            747..821
                     /locus_tag="MIV85_003366"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Gly,seq:gcc)
     gene            831..904
                     /locus_tag="MIV85_003367"
     tRNA            831..904
                     /locus_tag="MIV85_003367"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:865..867,aa:Arg,seq:tct)
     gene            1888..2727
                     /locus_tag="MIV85_003368"
     CDS             1888..2727
                     /locus_tag="MIV85_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBY2962677.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETISFFKGG
                     IFK"
     gene            2724..3905
                     /locus_tag="MIV85_003369"
     CDS             2724..3905
                     /locus_tag="MIV85_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962678.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4209..5111
                     /gene="ptb"
                     /locus_tag="MIV85_003370"
     CDS             4209..5111
                     /gene="ptb"
                     /locus_tag="MIV85_003370"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBY2962679.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5133..6212
                     /gene="buk"
                     /locus_tag="MIV85_003371"
     CDS             5133..6212
                     /gene="buk"
                     /locus_tag="MIV85_003371"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBY2962680.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6202..6879
                     /locus_tag="MIV85_003372"
     CDS             6202..6879
                     /locus_tag="MIV85_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2962681.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6922..7137
                     /locus_tag="MIV85_003373"
     CDS             6922..7137
                     /locus_tag="MIV85_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2962682.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7166..8245
                     /locus_tag="MIV85_003374"
     CDS             7166..8245
                     /locus_tag="MIV85_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBY2962683.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8245..8997
                     /locus_tag="MIV85_003375"
     CDS             8245..8997
                     /locus_tag="MIV85_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBY2962684.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8998..9555
                     /locus_tag="MIV85_003376"
     CDS             8998..9555
                     /locus_tag="MIV85_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBY2962685.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9725..11071
                     /locus_tag="MIV85_003377"
     CDS             9725..11071
                     /locus_tag="MIV85_003377"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBY2962686.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11338..>12831
                     /gene="glmS"
                     /locus_tag="MIV85_003378"
     CDS             11338..>12831
                     /gene="glmS"
                     /locus_tag="MIV85_003378"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBY2962687.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISREDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEA"
BASE COUNT         4932 a         1568 c         2580 g         3751 t
ORIGIN      
        1 gaaatattaa gcataaagat tatgtggtta caatagcaga gaggatacac ctgttcccat
       61 tccgaacaca gaagttaagc tctctagcgc tgatggtact tggtgggaaa ctgcctggga
      121 gagtaggacg tagccacgtt aaatgttcca aggtagctca acggtggagc aaccggctgt
      181 taaccggtag gctgtgggtt cgagccccac ccttggagcc aaaaaagccg aagtggcgga
      241 actggcagac gcacaggact taaaatcctg cgggacttac ctctcgtacc ggttcgattc
      301 cggtcttcgg cacttataaa acaatatcgc ggggtggagc agttggcagc tcgtcgggct
      361 cataacccga aggtcgtagg ttcaagtcct gcctccgcaa ccattaaaac ggctcgttgg
      421 tcaagaggtt aagacaccgc cctttcacgg cggtaacagg ggttcaattc ccctacgagt
      481 caccaattca attaaatatg cgggtgtagc tcaatggtag agttctggcc ttccaagcca
      541 gctgtgaggg ttcgatcccc ttcacccgct ccaaaaatgg gaccatagct cagctgggag
      601 agcacctgcc ttacaagcag ggggtcacag gttcgagccc tgttggtccc accattcgcg
      661 gcctggtagt tcagttggtt agaatgccag cctgtcacgc tggaggtcga gggttcgagc
      721 cccttccagg tcgccaaatt aaataagcgg gaatagttca gtggtagagc gcaaccttgc
      781 caaggttgaa gtcgcgagtt cgaatctcgt ttcccgctcc ataataactt gggtgcatag
      841 ctcagctgga tagagcaacg cccttctaag gcgtgtgtcc ggggttcgaa tccctgtgcg
      901 ctcattaaga aaagtttact ataaattata gtaaactttt atattgttta aaaagacaca
      961 ggaaacatgt atattacctg tgtcttttta tttataaact ttaaactatg taaaaattac
     1021 agtatattct aatagagtta cagtatattc attaatattg taaacatacg gagggtaatg
     1081 tataatagtc tacaagatgt ttatgaaggc atcagttaaa tataataaat ataactaatt
     1141 agtaagagtt atatacatta tattgtatac tttatggtat ttatatattg aaataactta
     1201 tgaaattatt tataaagaga ttcatgagca tatttttgtc taaacaataa gtataagaaa
     1261 ttataaaaaa ttagagacta tagtgaattt acaatttaat gtaatattta taagttatac
     1321 taaataaatt attatactgt gaaatggata tataacttta ggtattgtgt attattttca
     1381 ctgtaggaga ttatatctag ttatacataa taagttttaa tgatagttta tagtaagata
     1441 ttaaaataaa tttatctaat ctagatatga aataagttat tactttaata taaaaatgaa
     1501 tctaatggaa taatattgat gataagtaat atttagattt tgtatttgtt tatagttaat
     1561 aagtggatta tagaatttat aataattaat atatattaaa caaagatata ttaagatatt
     1621 ttagaacata aaactgaatt aaggcgcgag tactattttg tattcgcgcc ttgatggttt
     1681 gagttatttg agtaaaaact aactttaata agaaatatgt atttattaag ttgatatttt
     1741 taatgtgttt agagattatt taacaatctc caaatataaa actagaatta tttacataaa
     1801 agttaaatag tttgtataga gttagattta tatagtataa tacttagtgt aaataattaa
     1861 gaagttatca aacaggagga taaaactgtg ttagatataa attctttttt aaatggattt
     1921 tttaatataa tattaagaat gagtatatat gatttaattg acatatctat agtagcgtat
     1981 attttttaca aaatatttat gtttataaaa gatacaagag cagaacaagt gtttaaaggt
     2041 ataatctttc ttttattagc aactcaactt agtaacacct ttaaattgca taccgtttat
     2101 tggatatctc ttaaagcttt agattatgga gttatagctg ctcttataat ttttcaacca
     2161 gaatttagag caggacttga acatatagga agagcaaagt ttaatttatt tggaaagaat
     2221 gtaaatactt ctgaagaaac tctcaataga aatatagaag aaattgtaga agctttatat
     2281 tcactttcta gacaaaaaat aggagctctt atcataatgg agagagaaac tagaataagt
     2341 gatataataa atacaggaac tattattgat gctgaaattt ctaggcaact attaataaat
     2401 atatttatac caaatacacc attacacgat ggagctgttg taattagaga ttctaaggta
     2461 aaagcagctg catgtttttt gccattgaca gaaagtaagg atttaagtaa agatttgggc
     2521 actagacata gagcaggaat aggggtaagt gaggtgtctg actgtataac tctgattgta
     2581 tcagaggaaa caggtggcgt atcaattgct aaagcaggta agttatatag agatatttct
     2641 agagaaagaa tgatgaatat attacgtagt aatttaaaaa caaatacaga aacaataagt
     2701 tttttcaaag gtggtatatt taaatgataa atagactaaa aaataatacc aaaataaaaa
     2761 taatatcatt tttaagtgca attgcattat ggatgtatgt tatggctgta gttgaccctg
     2821 aagaaactaa agggtttgaa gatatacctg tatctataag taatatgagt gatttaaagg
     2881 ataaaaatct tgttatatat ccagacgaaa aattaacagc agatgtatat ataaaaggta
     2941 gtttatcaaa ggtacaaagt gttaaaaaag aagatataca tgtatatgga accattgaag
     3001 acccaataca aggacagaag gaagtatatt taaaagcaaa tattcctcaa ggtgttactc
     3061 tagaatttaa gcatgatgtt ttagtagtaa atcttgaaaa aaacataaaa gaaaaaagag
     3121 atataaaggt agaagtaagt ggaaattcaa aaagaaatat aaataaaatt gaacttagta
     3181 aggaatttgt cgatgtatca ggtccaagaa ctctagttaa agaagtcaaa agtgtaagag
     3241 ctaatctaga tgttggtaat gagacagatg atttttctaa aaaattgcaa ttaataccat
     3301 taaatagtga tggaactaag gttgaaggag taacattaag ttcatccttt gtgactgcaa
     3361 agatagaact attgaaggaa aaaattgtcc caataagagt aagtctaaat gataataaag
     3421 ataatgatgt actgaaaaat tataaattaa gtaaggaaca agttacaata aaaggaaaga
     3481 aagaagatat agacaaaata agttatatta agacaaaacc tattgactta gctgatttgg
     3541 ctaatggtga agaaaaagaa gttagcttag aaattccaga gggtataact cttgaggata
     3601 gctctataac aattaaatta aatgatacaa aacaattgag tgcagaattt ttatataatg
     3661 cgggagatat tgaattaaga aatatcccaa caaatatgga taatccaaat gtaatttctg
     3721 atgtagatat aaaagttgtt gtagagtcaa cggaggattt gagtaagtta aataaaaaag
     3781 atatttcatt atatattgat ttatcacaag gtcctgagga agatagtaaa tataaaataa
     3841 aatatgaaac aacatatcaa tttaaaaaaa taaatataga acctaatatt gttgaagtgg
     3901 aatgaacaaa tatttcgaat atttagttgt tacaagatgc gacaaaaaaa cctataaaat
     3961 taagtttgtt aattttatgt ttttgttgca tcttgtttat tttagttata ttataaaata
     4021 aggacaatga gatatttgtt aaatctaaaa agcgctagat atatgaaaaa agactgataa
     4081 atagatttaa ataaatattt tgaattaaat atttcaatta tctctaggaa aacgttgctg
     4141 aacgagttat aatttaattg agatataaaa agttctattt caaaaaattc aagatgaggt
     4201 ggaaatgcat gagaagtttt gaagaagtaa ttaagtttgc aaaagaaaga ggacctaaaa
     4261 ctatatcagt agcatgttgc caagataaag aagttttaat ggcagttgaa atggctagaa
     4321 aagaaaaaat agcaaatgcc attttagtag gagatataga aaagactaaa gaaattgcaa
     4381 aaagcataga catggatatc gaaaattatg aactgataga tataaaagat ttagcagaag
     4441 catctctaaa atctgttgaa ttagtttcac aaggaaaagc cgacatggta atgaaaggct
     4501 tagtagacac atcaataata ctaaaagcag ttttaaataa agaagtaggt cttagaactg
     4561 gaaatgtatt aagtcacgta gcagtatttg atgtagaggg atatgataga ttatttttcg
     4621 taactgacgc agctatgaac ttagctcctg atacaaatac taaaaagcaa atcatagaaa
     4681 atgcttgcac agtagcacat tcattagata taagtgaacc aaaagttgct gcaatatgcg
     4741 caaaagaaaa agtaaatcca aaaatgaaag atacagttga agctaaagaa ctagaagaaa
     4801 tgtatgaaag aggagaaatc aaaggttgta tggttggtgg accttttgca attgataatg
     4861 cagtatcttt agaagcagct aaacataaag gtataaatca tcctgtagca ggaagagctg
     4921 atatattatt agccccagat attgaaggtg gtaacatatt atataaagct ttggtattct
     4981 tctcaaaatc aaaaaatgca ggagttatag ttggggctaa agcaccaata atattaactt
     5041 ctagagcaga cagtgaagaa actaaactaa actcaatagc tttaggtgtt ttaatggcag
     5101 caaaggcata attttaaggg ggaaataggc aaatgagcaa aatatttaaa atcttaacaa
     5161 taaatcctgg ttcgacatca actaaaatag ctgtatttga taatgaggat ttagtatttg
     5221 aaaaaacttt aagacattct tcagaagaaa taggaaaata tgagaaggtg tctgaccaat
     5281 ttgaatttcg taaacaagta atagaagaag ctctaaaaga aggtggagta aaaacatctg
     5341 aattagatgc tgtagtaggt agaggaggac ttcttaaacc tataaaaggt ggtacttatt
     5401 cagtaagtgc tgctatgatt gaagatttaa aagtgggagt tttaggagaa cacgcttcaa
     5461 acctaggtgg aataatagca aaacaaatag gtgaagaagt aaatgttcct tcatacatag
     5521 tagaccctgt tgttgtagat gaattagaag atgttgctag aatttctggt atgcctgaaa
     5581 taagtagagc aagtgtagta catgctttaa atcaaaaggc aatagcaaga agatatgcta
     5641 gagaaataaa caagaaatat gaagatataa atcttatagt tgcacacatg ggtggaggag
     5701 tttctgttgg agctcataaa aatggtaaaa tagtagatgt tgcaaacgca ttagatggag
     5761 aaggaccttt ctctccagaa agaagtggtg gactaccagt aggtgcatta gtaaaaatgt
     5821 gctttagtgg aaaatatact caagatgaaa ttaaaaagaa aataaaaggt aatggcggat
     5881 tagttgcata cttaaacact aatgatgcta gagaagttga agaaagaatt gaagctggtg
     5941 atgaaaaagc taaattagta tatgaagcta tggcatatca aatctctaaa gaaataggag
     6001 ctagtgctgc agttcttaag ggagatgtaa aagcaatatt attaactggt ggaatcgcat
     6061 attcaaaaat gtttacagaa atgattgcag atagagttaa atttatagca gatgtaaaag
     6121 tttatccagg tgaagatgaa atgattgcat tagctcaagg tggacttaga gttttaactg
     6181 gtgaagaaga ggctcaagtt tatgataact aatgataaaa gaataagaat cataactggt
     6241 cactatggaa gtggtaaaag tgaatttgcg atgaactatg ttgttaagtt aagagatatg
     6301 gtttctggca aagttgctat agccgattta gatgtggtaa atgtatactt tagaactaga
     6361 gaaaagaaag agttaatgaa atccttaggt atacaaccaa tagatagctc aattaatgct
     6421 ccaacattag acttaccagc agtatcagca gaggtaatgt ctcctatggt agaccattca
     6481 tacaattctg ttatagattt aggtggagat aatgtaggtg ctagggttat aggaagattt
     6541 agtcatttgt taaaagaagg cgattatgat atgctttttg taataaatgc aaatagggag
     6601 aaaactcaaa cttctgaaga agttatccaa tatataaaag aaatagaaaa atcttctaaa
     6661 ttaaaggtaa caggtctaat taataatact catcttatta ggtttactac tattgatgat
     6721 gttttaagag gtcagaaagt tgcaaaagaa gtttctgaaa aatgtaatat accgataaga
     6781 tatgttgcat gtttagaaaa tcttgttgaa cagttaccaa aagatttaga aggagaaatt
     6841 tttcctataa aattatatat gagagaagac tggatgtagt ttgagctcaa atatatagaa
     6901 agtttaagga ggcttaggta aatggctaaa ggaaaagtat cttttaatca agaacgttgt
     6961 aaaggttgtg gattgtgtgt tgaagcatgt ccagtaaaaa tcatacaatt agactcaaat
     7021 gtaataaaca aaaaagggta taacccagca actgtttttg aaatggaaaa atgcatagga
     7081 tgtgcaagtt gtgcaactat gtgtccagat gtagttataa cagtagaaag agattaattt
     7141 aattaatatt taagggggaa ttttaatggc taagatactt atgaaaggta acgaagcatt
     7201 tggaaaagca gctatagaag ctggttgcaa atatttcttc ggttacccaa taactccaca
     7261 aagtgaatta ccagaatatt tatcaagaga gttacctaaa ataggtggag cgttcgttca
     7321 agctgaatca gaagtttctg cgataaacat ggtttatggt ggagcaggtg caggagcaag
     7381 agttatgact tcttcatctt caccaggagt tgctttaaag caagaaggta taacatatgc
     7441 agtaggagca gaagttcctt gtgttgtact taatgtaatg agaggtggtc caggacttgg
     7501 aagtatacaa ccttcacaag ctgactactt tatgtctaca agaggtggag gaaatggaga
     7561 ctacagaact ccagtattcg caccagctac agttcaagaa gctgttgata tgataatgga
     7621 agcttttgac gttgcagatt attacagatc accagttatg gtagttgcag atggtatgat
     7681 aggtcaaatg atggagccag ttgaatttag agctcctgag aagaaaagag aattgcctcc
     7741 taaagattgg gcaactgttg gaactaaagg aaaaagaaaa cctaatgtaa taaactctct
     7801 atacttagag ccagaagtac tagaagacca ttgttggcat ttacaagaaa aatttgatgc
     7861 aatggaaaag aatgaagtac aatacgaaat gtacaaaaca gaagatgctg aatttgtatt
     7921 tgcagcttat ggaactactt caagagtagt aaaaagcgca attgatatat taagagaaga
     7981 aggaataaaa gcaggtctta taagacctaa agtattatgg ccattcccat tcgaagcatt
     8041 caaccaaatt cctaatgcta gaaacatatt gactgttgaa atgagtatgg gacaaatggt
     8101 ggaagatgtt aaaatggcag tagaaggtaa attaccagtt tacttccatg gaagaccagg
     8161 aggaatgact ccaacaccag cagaaatagt tgaaaaagct aaaaaaatta ttgccggaga
     8221 attggttgca ggaggtgcta gataatggct gttgtattta agaaaactga aggattacaa
     8281 gatactcaaa ctcactactg tccaggatgt acacatggta taatccatag attagttggt
     8341 gaagtattag aagaactagg agtattaggt gatgctgtag gtgttgttcc agttggatgt
     8401 tcagttttag gatataaata ttttaactgt gacactcaag aagctgctca tggtagagcg
     8461 ccagctgctg ctacaggaat aaaaagagtt catcctgaaa atacagtatt cacttatcaa
     8521 ggtgatggag acttagcttc aattggtact gctgaaatag ttcatgcagc tgctagagga
     8581 gaaaaaataa ctactatatt tgtaaacaat acaacttatg gtatgactgg tggacaaatg
     8641 gctccaacta cattagttgg acaaagagct actactgctc aatcaggaag aaatgctgaa
     8701 actcaaggtt atccaataag agtaagtgaa atgttagcta cattaacagg agctgtattt
     8761 gtagaaagag tagcagttga tactccagct catgttagac aagctaaaaa agctataaag
     8821 aaagcattcc aagttcaaca agcaggatta ggatttggaa tagtagaagt attatctact
     8881 tgtcctacaa actggggact agctccaaat gatgctttac aatggttaag agacaacatg
     8941 ataccatact atccattagg aaatttcaaa aatgttgaag ttgaggaggt gaagtaaatg
     9001 tctacagcta gagtaatatg tgcaggcttc ggaggccaag gtgttatgtc tatgggacaa
     9061 ttacttactt atgcaggaat gctagaagga aaagaagttt cttggttacc atcttatgga
     9121 ccagaaatgc gtggaggtac agcaaactgt gcagtaactg tatctaatga gccagttggt
     9181 tctccactta taacagatga tgcaactgca gctatattat taaatatacc agcatttgaa
     9241 aaattcaaag atgatgttat tcctggtgga aaaataatag taaatagttc tttaataaaa
     9301 gaaaaagttg atagaacaga tgtagatgtt tattatatac cagcaaatga attagcagct
     9361 gaattaggaa atgataaagt tgctaacatg ataatgttag gtgcttactt aaaagtatct
     9421 gatactgtag atatagaatc tgtactagaa gcattcaaaa aagttttcgg acctagaaaa
     9481 gaaaaattcg ttccattaaa cagagaagct ttacaaaaag gtatggatgc tacatgttct
     9541 aaagcaacta actaataaag aaaaagatgt caaaaaaaag acaatagaat tatttctatt
     9601 gtcttttttg ctgataagta ttaaaatatt tttatgactg aaattaagcc tataatgata
     9661 ttttatgaac tataaaaata taatacaaat tacaagcttt tcaattatga aaggagaatc
     9721 tttagtgaga aagtattttg gaacagatgg agttagagga gtagcaaata cagaactaac
     9781 atgtgattta gcatataaac ttggtagagc tggtggattt gtcttagctc aaggagacca
     9841 cagagtaaaa gtagtagtag gtaaggatac tagaatatca ggtgatatgt tggaagcatc
     9901 tttaatagca ggacttatgt ctgttggatg tgatgttatt actgttggaa taataccaac
     9961 acctgcagtg gcatatttaa ctagaaaata tggtgctgat tgtggtgtgg ttatatctgc
    10021 atctcacaat cctgttgaat ataatggaat caaattcttt aataagaatg gatataaatt
    10081 agatgatgaa attgaattga aaatagaaga atatatagac gatatagaca aaattgattg
    10141 tcttccaatt ggtgaaaatg taggaagaaa attacatgaa cattgtgcac aaagagacta
    10201 tgtagactac ctaaaatcaa taataagcac tgactttaag ggattaaaag tagttttgga
    10261 ctgtgctaat ggtgcgtcat ataaagtggc accaatagtg tttgatgaac taggagcaag
    10321 tgtaatttca ataaatagtt caccagatgg aaataatata aactataaat gtggctctac
    10381 acatccagaa caacttcaaa gggctgtttt ggaacataat gctgacttag gtcttgcata
    10441 tgatggagat gctgatagat taattgcagt aaatgaaaag ggtcaaattg ttgatggaga
    10501 ccatataatg atattgagtg ccttaaattt aaagaaaaat aataaattgg cacaagatac
    10561 tttggtagtt acagttatga gtaatatagg gttgacaata gctgctaagg aaaatggaat
    10621 aaatttatct actacagcag ttggagacag atatgtttta gaagatatgg ttaaaaatgg
    10681 atataatctt ggtggagagc aatctggaca tatgatattt ttagattaca acactactgg
    10741 agatggagtg cttagttctc taatacttgc aaatataatc ttgcaagaaa agaaaccttt
    10801 atcagaaatt gcatcaataa tgagccaata cccacaagta ttagtaaatg caacaataaa
    10861 aaatgaaaat aagaacaaat atatggaata tccagaaata aaaactgaga tagaaagaat
    10921 agaatctatt ttagacggaa atggtagagt tttgataaga ccatcaggaa ctgagccatt
    10981 agttagagtt atgttagagg gtaaagagga aggtcaaata aaagaattag caacaaactt
    11041 agctaatctt atacaagaaa aattatcgta atttaaaggg tattctcaga tataaatact
    11101 gaggacacct ttctaagcgc cagaacttag ttatagacat aattattgag taatatagga
    11161 actaagttga cgaggtcaga gttaatcgaa ttgtcggcgg atgctctgcg gtgtgtttac
    11221 catcgaaaga cttctttaaa taataggagc aatcctatgg acaaagggaa gccaaagtaa
    11281 acttatatga cctaactctt aaaatatata aataatattt ttaggaggac acaaataatg
    11341 tgtggaatag ttggatattt aggaagtaga aaggcagcag aagttatagt agaagggctt
    11401 tctaagctag agtacagagg ttatgactca gcaggagtag cagttaatag ttctaatgaa
    11461 aaagaactta atattagaaa gtttaaaggt agactttctg tacttgcaga agacttagaa
    11521 aagaatccta ttgatggaaa tttaggtata gggcatacga gatgggcaac tcatggagaa
    11581 ccatctgatg taaactcaca tcctcatttt aatcaagcca aaacaatagc agttgttcat
    11641 aatgggataa tagaaaacta tatggaaata aaagaagaat taatttctga aggtgttaag
    11701 tttgaatctc aaacagatac agaggtaata gcacatttag tagataaata ctatgagggt
    11761 aatttattag atgctgtata caaaactata tcaaaattaa gaggagctta tgcattaggt
    11821 gttatatgta aagaacatgg aaatgaatta gttgcagtaa gaaaagatag tcctcttgta
    11881 gttggtgtgg gtgaaggtga aaactttata gcatcagata tacctgcatt attaaaatat
    11941 actagagatg tttatttctt agaaaatgga gaagtagttc atctaaaaga cgaaaatgta
    12001 acagtttatg actctaatag aaatcttgtt gaaaaagaag tatttcatgt aacttgggat
    12061 gtagaagctg cgtctaaagg tggatatgac tactttatgt caaaagaaat tcatgagcaa
    12121 ccaacaggag taagagaaac tttagaaaga agacttgatg ataatggaaa tataattcta
    12181 gacagtataa atatttctag agaagactta gaaaaaataa ataaagttta tatagtggct
    12241 tgtggaacag catataatgc tggattactt ggtaagtatg ccatagaaaa atttgtaaat
    12301 ataccagtaa taactgatat agcatcagaa tttagatata gcgacccatt tgtagatgaa
    12361 aattcattag taatattagt tagtcaatct ggtgagacag cagatactct agcagtatta
    12421 agagattcaa aggctaaagg agcaagaata ctttcaataa ctaacgttgt aggttcatct
    12481 atagcaagag aatcagatga tgtattctat acttgggcag gacctgaagt agcagttgca
    12541 tcaactaagg catatactac tcaaataact tctttataca tgatagcttt ggactttgct
    12601 atcaaaaaag gaacaataac tagagaattt tatgatagta tgatttctaa gatgaaagaa
    12661 ataccatcaa aaatacaaga aatactagac aatgaagaat atataaaaga agttgctaaa
    12721 acagttgtta gttctgaaca tgcattctat ttaggaagag gtatagacta tagcttagca
    12781 atggaaggtt cattgaaatt aaaagagatt tcatatatac atgcagaagc t
//
LOCUS       DAGQVA010000103        12526 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.103, whole genome shotgun sequence.
ACCESSION   DAGQVA010000103 DAGQVA010000000
VERSION     DAGQVA010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.103"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(348..893)
                     /locus_tag="MIV85_003379"
     CDS             complement(348..893)
                     /locus_tag="MIV85_003379"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBY2962688.1"
                     /translation="MRVEPIENKKDIEKLKRYFRNKGKIRDLTLITLGLNTGFRIEDI
                     LKLRVKDVYKKREINIKESKTGKRIRKPINDSLKEILDIYCKDKPTNEYLFKSQKGEN
                     EAISTTQAYRIIKKASKACRIKLNIGTHSMRKTHGLHIFKDKGIEVAQRALNHANQID
                     TLTYIGVVQKQADNAIMKLNL"
     gene            complement(909..1157)
                     /locus_tag="MIV85_003380"
     CDS             complement(909..1157)
                     /locus_tag="MIV85_003380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962689.1"
                     /translation="MEGTKRSYRKIPKLDLRKVKLADVFEKNKSGVFRVEEADEQLLH
                     ECLDETKSIREEKHLTWQIQFKGKSVYCVFYEHPFWDL"
     gene            complement(1144..2079)
                     /locus_tag="MIV85_003381"
     CDS             complement(1144..2079)
                     /locus_tag="MIV85_003381"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962690.1"
                     /translation="MINIIDLRFYLRNDLFTNEELTEITKQITEENVFLYDIAEEKGC
                     HPYTLNKCLQRFEHSSMEVGKFIGEMSELHKEGALTTEELKLKFEIVKEILILIKRSE
                     EAEKILHLLENEKVKTVAEKLYKSRSSVYDILKQMGFKKNKYINVWYHIDNENIAGNV
                     ENTKRDVELVHLYQQRYDNFLKNYYLDSEIIDIDKNILDDIETLSEEFEYETVNDFIS
                     VLLLRGLQNERFKNKENINNKNDNNNIVKMKDVEHEIFFTQGAEMLEEYYKTNLIDVH
                     KISKTEIEEMNPKELMELYHLKNEGKAKEDFYGRD"
     gene            complement(2250..2897)
                     /locus_tag="MIV85_003382"
     CDS             complement(2250..2897)
                     /locus_tag="MIV85_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003411768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBY2962691.1"
                     /translation="MIIGYERVSTRKQDNSRQERVLENEGIKFDKIYRDKVTGATKER
                     EALNRMLLEVNEGDTVYCESISRLGRNLKDLIDIIDTLVQKGVRVKILKEGIDTGNNT
                     YKLLLGIFGAVAEMERETIQERTQQKIDQLKEDKKNTGEINTKSGKWFGRQKVTKELL
                     ETNKEFIKYYNKILDGSLKKNEVAKILNVGRTTLYEWIKVYEGGEIKRSNRAKKN"
     gene            complement(3487..3855)
                     /locus_tag="MIV85_003383"
     CDS             complement(3487..3855)
                     /locus_tag="MIV85_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004068822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962692.1"
                     /translation="MELDFKFIGQRIKIARIKKKLTQEVLSEKINVSPQHVSNIETGN
                     SSVSLPTLVAIANTLGVSVDELLCDTILSSKAVFENELEEVLRDCNEYEIRFITDIVK
                     ASKKSIRDIKLFQSNLNDRY"
     gene            3971..4303
                     /locus_tag="MIV85_003384"
     CDS             3971..4303
                     /locus_tag="MIV85_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2962693.1"
                     /translation="MDIPKIPQTELKVMKFIWSKNDIVTSKEVAKAMELEYSWKMTTT
                     LTILSRLVIKHFLASERIGRMTHYTILIAKKDYKISETKRFLNDIHSNSLESLLNSLK
                     DCNITHKK"
     gene            complement(4451..4888)
                     /locus_tag="MIV85_003385"
     CDS             complement(4451..4888)
                     /locus_tag="MIV85_003385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962694.1"
                     /translation="MRVKNIISIFVCALIIIMSVNVVSFAEQFNSSDIIFMEDGKEEI
                     NPFSVYILNGRCNLSFSNGKANVNASVVGKSGVTRTSIVTKLQELKGGSWVNLKTSTK
                     KTGGKTCSVLNSYSVTKGHTYRAVAIITAENESKTLISTSQKY"
     gene            complement(4957..5658)
                     /locus_tag="MIV85_003386"
     CDS             complement(4957..5658)
                     /locus_tag="MIV85_003386"
                     /inference="COORDINATES: protein motif:HMM:NF025643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HBY2962695.1"
                     /translation="MNKDKLDIEKLLYEQLPKIEEKILYELPCDEDIDYEFSIEFESK
                     MDKIIKENEKKVKKNTYKNLKKIAIVFIIILSSIVTITTIKTEAFPENLIRIMKKVYK
                     EFTDYNFINPHKSNVSFKYIEPKYISTGYKEVERIEEENYLSILYKDKLDNYIIYQMM
                     LYSRDVIVLDTEDAFVENIKFNNQYAQYVEKGNTQQLLWHDKNNIYMLSKELPTKKIT
                     KKDKKEFIKIAKNIK"
     gene            complement(5651..6196)
                     /locus_tag="MIV85_003387"
     CDS             complement(5651..6196)
                     /locus_tag="MIV85_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2962696.1"
                     /translation="MLIYLAIIDSKEERIKFEEIYIKYKKLMFYVANQILKDDVLAED
                     AVHSSFLKIIDNLDKVNDVNSPKTKGFVVIIVKRISINIYNRRKKEEISNINDDNYKF
                     SSLDLSIEKLGECSYLGEALKKLSETDLQVILLKYSHGFSIREISKLLNIKEVNLYKR
                     NKRALEKLKKILSEMEALSNE"
     gene            6332..7060
                     /locus_tag="MIV85_003388"
     CDS             6332..7060
                     /locus_tag="MIV85_003388"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962697.1"
                     /translation="MKSKRINKMLATTMTMAMLAIPAVTATSYAMESTGLGTEYTYNN
                     ESKQQEEWVKSFDTETGKEILLNKTTNEKVSEVYENVNGKLVKLSINEALEKFNLNEE
                     IITKSPKSIFGVSSVKKITGSARKISQDVSGGKQGATISIGNSTTVTESFTVGGTTEA
                     IKAAVRANAGFTWSKSLTRSVTTTHKVPAGKIGYVAFKPYYKEVRGTVNGILAGTSIT
                     QKIVAKSPLKAGKVCDGLEYLAYK"
     gene            7086..7334
                     /locus_tag="MIV85_003389"
     CDS             7086..7334
                     /locus_tag="MIV85_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004035436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962698.1"
                     /translation="MENKNMYLRVSLILAVLGFIILFFNNDLALSLKATYLADKGFED
                     IVENQILKNYSYMFLIIGGVLFSIGIYNLTKLKQINKK"
     gene            complement(7520..10129)
                     /locus_tag="MIV85_003390"
     CDS             complement(7520..10129)
                     /locus_tag="MIV85_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBY2962699.1"
                     /translation="MKIDIKQLIDIIKNANIDELYLRDIGVDTTQKRNVPCPIHGGKD
                     KNFQFDLNKRIYTCYSHNCVVGADIIELCRTYERFERPIEAILFLANKYNISLPINKS
                     KTNIKKTNNTIKNIYIKKKDINSFIEEKKQEAFKNNDIELAFEFECMTDKDKRKYYLD
                     NNIKIKSMLEKQNYSSYKADSIINIDKYISENLKGIRESIKHATEGKNVLMVAPTGSG
                     KTYSIINTLKELDIKALFIFPNSANVQQAIVEYKIAGAYDKIPTKHALEGNKLVAMTW
                     DKTEQLLKEDLSEYIIVIDEIHQTYTDAFRSKAIKSLNNITNKCRGRLDITATPSKLE
                     FEIYNKVIEYKQNIQTEYKVKLYDKINIGKVIEILNNSNNSMLLKDSISTLNYISKKV
                     NKKSGVVISDTKDTSKLYDRIVSYSDMEGYEVLLNTSVITAGVNINNPNVTDIIVIGE
                     KDVGKIKQYVARARGAKSINVHIFNSYKTTNEDSNVYSVEWCINENIKDVESLTNIYN
                     KASKRDLPYRAIGIDISPINIKNIDSNIYYDKKDMCYKTDKLYIKSNAYNNYYQTRTI
                     NSFKVLLEEYFNKIEIVETEKETKKIEEEIKEHEEAIKEFKKSAIEQLEGHKKYLVGY
                     SEIKKSMTSSNLLKYHHDMRIDNNICLKYYMEHDLYSLIINNNCRKTIDLFSDFVLDN
                     SYSIDLSWKLATMSDEKRNLFFEQINTTIYRKINKKYANSLLNDDNIGTYTYNYINFN
                     FGVGTSYTKEHLEALAVDLQTFLATKKKLTIKKISLILQSIFVIEVKQHRGVTGLPYK
                     YYKNILPNPVTDKKVIRVYTIKKHIDIEDIKKELGLIDNDLSIEHLVEARINKLLNAI
                     DETEKEVLLEGLI"
     gene            complement(10459..10761)
                     /locus_tag="MIV85_003391"
     CDS             complement(10459..10761)
                     /locus_tag="MIV85_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962700.1"
                     /translation="MLKDDLLRIGFDTYGVNLEDKLLENNEIYLNDKKESERIMNRLL
                     EILEEKEHKKMLIDFEEKVFGNSVIEKEYAYRMGVLDGLDLAEFIDLNKKLCLKRN"
     gene            10930..11133
                     /locus_tag="MIV85_003392"
     CDS             10930..11133
                     /locus_tag="MIV85_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962701.1"
                     /translation="MDIQINKLLENQNKTRYWLAKQIGMTHQNLTKLANNNTNSIKFD
                     SLEKICMALKCSPNELFGWEQDK"
     gene            11213..11758
                     /locus_tag="MIV85_003393"
     CDS             11213..11758
                     /locus_tag="MIV85_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962702.1"
                     /translation="MDRYTFDNLPIKEQIQYINNKLLEGNTLTNTCKDIGIGRTTIRN
                     RFKQHGYEFNPTKKLYISIIEVVELESSSKVVAGDTSNDNTLVDATNIDFNNILSKFN
                     DMNNKLNEVYSWYESQSSNKVVGADKLNIDDFKGNIVVRSYKVYEDIQKEFVAFCEAN
                     KKYRVQDIISQALRDFMDKYK"
BASE COUNT         4134 a         1982 c         1342 g         5068 t
ORIGIN      
        1 aaaaaaaaat aaccatacgc attgatttta cttaaattaa aagtgttttt cgagttgttt
       61 tttcacttag tttagtaatt ttgaaatatt ataatattaa gcttcaatat gtatctatta
      121 tcatttaata atcaattaat aatagatatt ttttctaaac aagataaaaa caatatctat
      181 accagtaata gcaatagata gaagtatata aaaaaatgta cgattactat aaactattac
      241 atttatttta gttgccttga tacattgcaa ttacttacac atacgcctat ttaattaatc
      301 attaactata aaatgtaaaa acagcaaaga aaatcataca tttttaacta taaattaagc
      361 ttcataatgg cattatcagc ttgtttttgt actaccccaa tataagttaa tgtatctatt
      421 tgattagcat ggtttaaagc tctttgtgct acttcaattc ctttatcctt aaatatatgt
      481 aaaccatgtg ttttcctcat actatgagta cctatattta attttattct acaagctttt
      541 gaagcttttt taataattct atatgcttgt gtagtgctta ttgcttcatt ctctcccttt
      601 tgacttttaa ataaatattc attagttggt ttatctttgc aatatatatc taatatttcc
      661 ttcaaactat catttatagg ctttcttatt cttttccctg tcttactttc ttttatattt
      721 atctctcttt tcttgtatac gtctttaact cttagtttta gaatatcctc tatcctaaag
      781 ccagtattta accctaaagt tattagggtt aaatctctta ttttaccttt atttctaaaa
      841 tatcttttaa gcttctctat atctttttta ttttcaatgg gctctactct catttaaacc
      901 actcctattt ataaatccca aaatggatgt tcataaaaaa cacaatatac acttttccct
      961 ttgaattgta tttgccaagt aagatgcttt tcttctctta tacttttagt ttcatctaaa
     1021 cattcatgta aaagttgttc atcagcttct tccactctaa aaacgcccga tttattcttt
     1081 tcaaatacat ctgctaattt tacttttctt aaatctaatt ttggtatttt tctataactt
     1141 cttttagtcc cttccataaa aatcctcctt agcttttcct tcatttttta aatgatatag
     1201 ttccattaat tcttttggat tcatttcttc aatttctgtt tttgaaattt tatgaacatc
     1261 tattaaattt gttttataat attcctctaa catttcagct ccctgtgtaa aaaatatctc
     1321 atgttcaaca tctttcattt taacaatatt gttgttatcg ttcttattgt taatattttc
     1381 tttattttta aatctttcat tttgaagccc tcttaaaagt aaaaccgata taaaatcatt
     1441 tactgtttca tattcaaatt cttctgacaa agtttctata tcatcaagaa tatttttatc
     1501 tatatcaata atttcactat ctaaataata gttttttaaa aaattatcat atctttgttg
     1561 atacaagtgt actagctcaa catccctttt agtattctca acatttcctg ctatattttc
     1621 attatcaata tgataccaaa cattaatata tttatttttc ttaaatccca tttgttttaa
     1681 aatatcatat acacttgacc ttgatttata cagtttttct gcaactgtct tgaccttctc
     1741 attttccaat agatgtaata ttttttcagc ttcttcagac ctttttataa gtattaatat
     1801 ttcttttaca atttcaaatt ttaatttcaa ttcttctgtt gttaaagctc cttccttatg
     1861 taattcactc atttcaccaa taaatttccc aacctccatt gatgaatgtt caaacctctg
     1921 taagcattta tttaaagtgt atggatgaca gcctttttcc tctgcaatat catataaaaa
     1981 cacattttct tctgttatct gcttagttat ttcagttagt tcttcattag taaataaatc
     2041 atttcttaaa taaaatctta aatcaattat attaatcact cctttttaat tatttttcat
     2101 acattaatct tatcaccaaa aaaattaaat ttaaatattc caagacatca tctggacgct
     2161 aaaaagtgtc gtttttatta atttaataat attatcaaaa aaaagagcaa agacagtccc
     2221 ctaaaataaa aaaagaacta gttataaccc tagttcttct ttgctctatt gcttcttttt
     2281 atttctccac cttcatatac ctttatccac tcgtaaagcg tagttctacc aacatttaat
     2341 attttcgcca cttcattctt ctttaaactt ccatcaagaa ttttattata atattttata
     2401 aattctttgt tggtttctaa aagctccttc gttacttttt gtctaccgaa ccattttcca
     2461 ctctttgtat ttatctcgcc agtatttttc ttatcctctt tcaactggtc tattttctgc
     2521 tgtgttctct cttgtattgt ttccctctcc atctctgcaa cagctccaaa tataccaagt
     2581 aataacttat aagtattgtt tcctgtgtct ataccttctt ttaatatttt tactcttaca
     2641 cctttttgaa ccaatgtatc tataatatca attaaatcct ttaaatttct acctagacga
     2701 cttatagact cacaataaac cgtgtccccc tcatttactt ctaacaacat tctatttaat
     2761 gcttctcttt cttttgtagc tcctgtgact ttatccctat atatcttgtc aaacttaata
     2821 ccctcatttt ctaaaactct ttcttgtctg ctattatctt gttttcttgt acttaccctt
     2881 tcatatccta ttatcataac actacccccg tttatcttgt tataataatt atacaatata
     2941 ttttccgttc ggtcaaacta tattttctat tttcacaata ccgaacgtat tttattgttg
     3001 atttccaatg attctatgta aaaataacat aaatatcata cgtacggtta aacgttggtt
     3061 tttccgaaca cgaacatatc acctttttta tatcaactat tccttaaata ttttatataa
     3121 aatcgccaaa atctttttat attttttagg caaccaagtt tttaaaacaa aaatggtata
     3181 tcagtaagaa ttatgttttc acacaatata attcttaatg atataccatt taagaacctc
     3241 ataagaggta gatagagata attacataat catcacatac gttttatcaa atctgttttg
     3301 taatagggtt tatacttaaa taataacaaa aataccgtat tttttctaca tttatacttt
     3361 ttttgttgat agtaaaatat ggaaattagt catattttca gttattaact cataagttta
     3421 tacaactttt atttaaatat aataaaaaca tcaataataa ttaaattatt gaagcatata
     3481 tttatattaa tatctatcat ttaaatttga ttgaaacagt tttatatctc taatggattt
     3541 tttagaagct tttacaatat cagttataaa tcttatttca tactcattac aatccctcaa
     3601 aacttcttct aactcatttt caaagacagc tttagaactt aagattgtat cacataataa
     3661 ttcatcaacc gacaccccaa gagtatttgc aatagcaacg agcgttggca aacttacact
     3721 tgaatttccc gtttcaatat tgctgacatg ttgtggacta acattgattt tttctgataa
     3781 aacttcttgt gttagctttt tcttgattct tgcaattttt atcctttgac ctataaattt
     3841 gaaatcaagc tccatatgcg tattcccttc ctacaagtat tcacacatat tgtaaccttt
     3901 cccaaagtat attataataa attaatagaa tgtttcatta tgatagttat agtgtataga
     3961 aaggaattat atggatatac caaagatacc tcaaacagaa ctcaaagtca tgaaatttat
     4021 ttggagcaaa aacgacattg taacatctaa agaagttgca aaagctatgg aacttgaata
     4081 tagttggaaa atgacaacaa ccctaacaat cttatcaagg cttgttatta aacacttttt
     4141 agcatctgaa cgaataggca gaatgacaca ttatacgata ctcatagcaa aaaaagatta
     4201 taaaatatct gaaacaaaaa gatttctaaa tgacatacat tcaaattcat tggaaagcct
     4261 tttaaactct ttgaaagatt gcaatattac acataaaaaa tagtacatga gtataaatta
     4321 tattattata cctatgtact atttaagttt ttctataatg ttcctatatc tatctaattt
     4381 tgattgattt agatacttct gtagtagttt tcaaaacgtt tcttaactct tgtaagtgta
     4441 ttttcttttt ttaatatttt tgagatgtac ttattaatgt ttttgactca ttttcagcag
     4501 taattattgc aacagctcta taagtatgtc cttttgtcac agaatatgag tttaaaacag
     4561 aacaagtttt tcctccagtt ttctttgtag atgtttttaa atttacccaa cttccgcctt
     4621 ttaattcttg taacttagtt acaatagatg ttctagttac tccagatttt ccaacaacag
     4681 aagcatttac atttgctttt ccattagaaa atgataaatt acatctacca tttaatatgt
     4741 aaactgaaaa aggatttatt tcttctttac catcttccat aaaaataata tcagatgaat
     4801 taaactgttc agcaaaacta acaacattta ctgacattat tattatcaac gcacatacaa
     4861 atattgagat tatatttttt actctcatta agtacctcct tataaaatct tatatattca
     4921 atataacaac taactagcac tattttagac aaaaatttac ttaatatttt ttgcaatttt
     4981 aataaattct tttttatctt tcttagttat tttttttgta ggtagctctt tagataacat
     5041 ataaatatta tttttatcat gccacaataa ttgttgagta tttccttttt caacatactg
     5101 tgcatactga ttattaaatt ttatattctc aacaaaagca tcctctgtat ccaagactat
     5161 aacatcccta gaatataaca tcatttgata aattatatag ttatctaatt tatctttata
     5221 taatattgat agataatttt cttcctcaat tctctcaact tctttatatc cagtagaaat
     5281 gtatttaggt tctatatatt taaatgatac atttgattta tgagggttta taaaattata
     5341 gtctgtaaat tctttatata ccttcttcat tattctaatt aaattttctg gaaaagcttc
     5401 tgtttttata gtagttatag tgactatact tgataaaatt attataaaaa caatagcaat
     5461 tttttttaag tttttatagg tgttcttttt tacttttttc tcattttctt ttataatttt
     5521 atccatttta ctttcaaatt ctatagaaaa ttcatagtca atatcttcat cacaaggtaa
     5581 ttcatacagt attttttctt ctatttttgg aagctgttcg tataataatt tttctatgtc
     5641 taatttatct ttattcattt gataatgcct ccatttcgct taaaattttt tttaattttt
     5701 ctaatgctct tttatttctc ttatacaaat taacctcttt tatattcagt agtttagaaa
     5761 tttctctgat agaaaaacca tgactatatt ttaagagaat cacctgtaaa tctgtctctg
     5821 acagtttttt taaagcttct cctaaataac tacactcacc taacttttca atcgataaat
     5881 ctaaagagct gaatttatag ttatcatcat taatattact tatttcctct ttttttcttc
     5941 tattatatat atttattgaa atccttttta ctataataac aacaaaacct ttagtttttg
     6001 gactattcac atcatttact ttatcaagat tatcaattat ttttaaaaat gaactatgaa
     6061 cagcatcctc cgctaaaaca tcatctttta aaatttgatt agctacataa aacattaatt
     6121 tcttatattt aatatatatt tcttcaaatt taattctttc ttcttttgaa tctataatag
     6181 ctaaatatat taacataaat tattctccct taaaaaatat tatccttaaa aaaattatat
     6241 acaatttata aaaaattata tataaatgtc taaaaataaa aacttcattt gttatatata
     6301 taaataaaaa cataaaagga tggtgtttta tatgaaatca aaaagaataa acaaaatgtt
     6361 agcaactaca atgacaatgg caatgctagc aataccagca gtaacagcaa catcatatgc
     6421 aatggaatca acagggttag gaacagaata tacatataat aatgaatcta aacagcaaga
     6481 agagtgggtt aaatcattcg atactgaaac aggaaaagaa atattattaa ataaaactac
     6541 taacgaaaaa gtttctgaag tatatgaaaa tgtaaatgga aaattggtta aattaagtat
     6601 taatgaagca ctagaaaaat ttaatttaaa tgaggaaatt atcacaaaat ctcctaagtc
     6661 tatttttgga gtatcaagtg ttaaaaaaat tactggttct gcacgcaaaa tatcacaaga
     6721 cgtatcaggt ggaaaacaag gtgctactat atctatagga aattcaacaa ctgtaactga
     6781 aagttttact gttggtggaa ctacagaagc aataaaggca gcagtaagag caaatgcagg
     6841 atttacatgg agcaaatctt taacaagaag tgtcacaact acacacaaag tacctgcagg
     6901 taaaatagga tatgtagcat ttaaaccata ttataaagaa gtaagaggta cagtaaatgg
     6961 gatacttgca ggaacttcta taactcaaaa aatagtagca aaaagtcctc ttaaagcagg
     7021 aaaagtttgt gatgggttag aatatcttgc atacaaataa taaataatag aaagagttga
     7081 ttaaaatgga aaataaaaat atgtacttaa gggttagttt aatattagca gtattaggct
     7141 ttataatatt attttttaat aatgacttag cattatcact aaaagcaaca tacttagctg
     7201 ataaaggctt cgaagacata gttgaaaatc aaatattaaa aaactattcc tatatgtttt
     7261 taataatagg tggtgtacta ttttccatag gaatctataa cttaaccaaa ctgaaacaaa
     7321 ttaataaaaa ataaataaaa taagaggact tataaattat aagtcctttt attttacact
     7381 tataagctac tttcaacctt tcatgattta acctttattt atacaacacc caaaactcga
     7441 cctcaaaaag agaacaggac ttcgtccccc ttaatacaaa gcaacatttt ttagtactat
     7501 tcgtacttaa gattagctat tagattaatc cttccaaaag aacctctttt tccgtttcat
     7561 caatcgcatt taaaagttta tttattctag cttcaactaa atgctctatg cttaaatcat
     7621 tgtctattag tcctaattct ttttttatgt cctctatgtc tatatgtttc ttaatagtgt
     7681 aaactctaat tactttttta tctgtcacag ggtttggaag tatattttta tagtatttat
     7741 agggcaaccc tgtgacaccc ctgtgttgtt tgacttcaat aacaaaaatt gattgtaata
     7801 ttagacttat tttcttaata gttagctttt tcttagttgc taaaaacgtc tgtaaatcaa
     7861 cggctagagc ttctaagtgt tcttttgtat aacttgtacc aactccaaaa ttgaagttta
     7921 tataattgta agtataagta ccaatattat catcatttag caaagaattt gcgtattttt
     7981 tattaatttt tcgataaatt gttgtattta tctgttcaaa aaatagattt cttttctcgt
     8041 ctgacattgt cgcaagtttc caagataggt caatactata actattatct aatacaaaat
     8101 cactaaataa gtctatcgtt tttctacaat tattattaat tattaggcta tataaatcat
     8161 gttccatata atattttaaa cagatattat tatctatcct catgtcatga tgatatttta
     8221 ataagttact gctggtcatt gacttcttaa tttcactata gccaactaga tactttttat
     8281 gtccttctag ttgttctata gctgatttct taaattcctt aatagcttcc tcatgctctt
     8341 ttatttcttc ctctattttt ttagtttctt tttcagtttc tactatctca attttattaa
     8401 aatattcctc taatagcact ttgaagctgt ttattgttct tgtttggtaa tagttattgt
     8461 aagcattact ttttatgtat aacttgtccg ttttatagca catatctttt ttatcatagt
     8521 atatattact atcaatgttt tttatgttta tagggcttat atcaattcct atagctctat
     8581 atggtaagtc tctcttagaa gctttattgt atatatttgt taggctctca acgtctttta
     8641 tgttctcatt tatgcaccat tcaaccgaat atacattgct atcctcattt gtcgttttgt
     8701 aactattaaa aatatgtaca tttatacttt ttgcccctct agctcttgca acatactgtt
     8761 ttatttttcc tacatccttt tctccaatta caataatatc tgttacatta ggattattta
     8821 tgtttacacc tgccgtgatt acagacgtat ttaaaagcac ctcatagcct tccatatcgg
     8881 agtaactaac aattctatca tatagtttgc tagtgtcttt agtatctgaa ataacaactc
     8941 cactcttttt attaactttc tttgatatat agttaagtgt tgatatacta tcttttaaaa
     9001 gcattgaatt atttgaatta tttagtatct ctattacttt cccaatattg attttatcgt
     9061 ataacttaac tttgtattcc gtttgtatat tttgtttata ttcaataact ttgttatata
     9121 tctcaaattc taatttagag ggtgttgcag ttatatctag tctacctctg cacttattag
     9181 ttatattatt taagctcttt attgctttgc ttctgaacgc atctgtgtaa gtctgatgta
     9241 tttcatcaat aactattatg tactcgctca aatcctcttt tagaagctgt tcagtcttat
     9301 cccacgtcat agccactaac ttgtttccct ctaaagcgtg tttagtaggt atcttatcat
     9361 atgcaccagc tattttatat tcgactattg cttgttgcac attcgcagag ttggggaata
     9421 taaagagtgc ttttatatcc agctctttta atgtatttat aattgagtat gtttttccac
     9481 ttcctgtagg agctaccatt aatacgttct taccttctgt agcatgttta attgactctc
     9541 taataccttt tagattttca cttatgtatt tatctatatt aattatcgaa tcagctttat
     9601 aacttgaata gttttgtttt tctagcatgg attttatttt aatattgtta tctaagtaat
     9661 actttctttt gtccttatca gtcatacact caaattcaaa agctaactca atatcattgt
     9721 ttttaaaagc ttcttgtttc ttttcttcta tgaagctatt tatatctttt ttctttatgt
     9781 aaatgttttt aatagtatta tttgtttttt taatatttgt cttactcttg ttaattggta
     9841 atgagatatt atatttattg gctaggaata aaatagcttc tataggtctt tcaaagcgtt
     9901 catatgtgcg acataattca attatatcag caccaacaac acaattatgg ctatagcatg
     9961 tatatattct tttgtttaaa tcgaattgga agtttttatc cttaccacca tgaattgggc
    10021 aaggaacatt ccttttttga gttgtatcga ctcctatatc tcttaaatat agttcatcta
    10081 tattggcatt ttttattata tcaattaatt gttttatatc tattttcatt tgtaaaaatc
    10141 cccctttttt agttaggggc taatcaagtt ttatcaagct atgtatttac attctgccgt
    10201 aaatctcgta taattaacat ataaaagaat aaggaaatat atattttata tgttaattaa
    10261 gcctaagtga ttagctccta gtattaaccc ctagtggcta actcctaatc ttgattaacc
    10321 cttaaatgga aagaatgagt ggatgccgtc aaacaaatac tcgttctttt tcgttttttt
    10381 tgttattagt attatatcac tattaaagtt ataattcatt gtttagaatt atttttctga
    10441 cggttttaat atatattttt aatttctttt caagcataat tttttattta agtctataaa
    10501 ttcagctagg tcaagcccat ctaaaacccc cattcggtat gcgtattctt tttcaattac
    10561 actgttacca aatacttttt cctcaaaatc aattagcatt tttttatgtt ctttttcttc
    10621 caatatttct aacaatctgt tcattattct ttcagattct tttttgtcat ttaaatatat
    10681 ttcgttattt tctagtagtt tatcttctaa atttactccg tatgtgtcaa atccaattct
    10741 taataaatca tcttttaaca ttacttttaa cactcctttt tatgcacact taaatctttt
    10801 gcacccctaa atatggtaat atattctatt tattattatg taattattta ctatgtattg
    10861 tcaagcatat atattgtttt tggtacatat ttccgatact atataataaa aaaggtggcg
    10921 attaaattgt tggatataca aataaataaa ttattggaaa atcaaaataa aacacgttat
    10981 tggttagcaa agcaaattgg aatgactcat caaaacttaa ctaaactagc caacaataat
    11041 acaaattcta ttaaatttga ttctttagaa aaaatttgta tggctctaaa atgttctcct
    11101 aacgagctgt tcggttggga gcaagacaaa taaaaaaata taaatcctaa agggtttatt
    11161 tataactact agaaaactac tttagtagtt attttatttt ggaggtttaa acatggatag
    11221 atatacattt gataacttac ctatcaagga gcaaatacaa tatattaata acaagctctt
    11281 agagggcaat acattaacta acacatgtaa agatattggt attggtcgta caactataag
    11341 aaatagattt aaacaacatg gatatgaatt taatccaact aagaagctat atatatctat
    11401 tattgaggtt gtcgaattag aaagtagttc aaaagtagtt gcgggcgaca ctagcaatga
    11461 caatacttta gttgatgcaa ccaatattga ttttaataac attttatcta aattcaatga
    11521 tatgaataat aaactaaatg aagtatatag ttggtacgaa tcacaaagta gtaataaagt
    11581 agttggggct gataaactaa atatagacga ttttaaaggc aatatagttg ttagaagcta
    11641 taaggtctat gaggatattc aaaaagagtt tgtagccttc tgtgaagcta ataagaagta
    11701 cagggtacaa gatattatca gccaagctct tagggatttt atggataaat ataagtagtt
    11761 ttacttactt tctgatattc taaaaacttt tcaatgaaaa tctcattttt tggcttcctg
    11821 tgaaaaatat gtactccttc cagtcctcta tctttattta ctttattaat ccgatagggg
    11881 gcgtattata tatatttcta tcgagcatat actcatcaaa acatagcatt agtttgatta
    11941 ttatatttct atttatttta agattatata tacaatttgc cccttaatac attgcaatta
    12001 ctaacttctt tagttttgat attaatattt aaatcattcc tttttaaagg tgctataagt
    12061 gctatatagg cattgcaacc tatatacttt ttaggggtgc agttgcatat gcaagctctt
    12121 tatttcccaa cacttaacca gttataaata tttatatcct ttattagcca aatatagcat
    12181 tttaaacaac tccgactatc tttagtagta acattttaca tagctttatt aatgtatttt
    12241 tgcatctgca accatgtttt taagttgcaa caccccaccc ccacacctta cacaaaacaa
    12301 tacttatctc cgaagccata tacctacctc ggttcacata tttttcttca acagcgttat
    12361 tttcagcaag gggggctaaa cattatactt tttttcagtg cattaaatag ccttacatgt
    12421 attggtataa ctttatttca aacccttaat tgaattgttt caatctaaat taagtaaatt
    12481 ttaataagat aaaatatata gtttgtaact ttatttcaaa atacag
//
LOCUS       DAGQVA010000104        12343 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.104, whole genome shotgun sequence.
ACCESSION   DAGQVA010000104 DAGQVA010000000
VERSION     DAGQVA010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.104"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            5..655
                     /locus_tag="MIV85_003394"
     CDS             5..655
                     /locus_tag="MIV85_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBY2962703.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(795..2171)
                     /locus_tag="MIV85_003395"
     CDS             complement(795..2171)
                     /locus_tag="MIV85_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2962704.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2187..4100)
                     /locus_tag="MIV85_003396"
     CDS             complement(2187..4100)
                     /locus_tag="MIV85_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBY2962705.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4236..4868
                     /locus_tag="MIV85_003397"
     CDS             4236..4868
                     /locus_tag="MIV85_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBY2962706.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5007..5546
                     /locus_tag="MIV85_003398"
     CDS             5007..5546
                     /locus_tag="MIV85_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBY2962707.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(5722..5892)
                     /locus_tag="MIV85_003399"
     CDS             complement(5722..5892)
                     /locus_tag="MIV85_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2962708.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6177..7244
                     /locus_tag="MIV85_003400"
     CDS             6177..7244
                     /locus_tag="MIV85_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBY2962709.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            7414..9315
                     /gene="cooS"
                     /locus_tag="MIV85_003401"
     CDS             7414..9315
                     /gene="cooS"
                     /locus_tag="MIV85_003401"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBY2962710.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAECIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            9308..9781
                     /locus_tag="MIV85_003402"
     CDS             9308..9781
                     /locus_tag="MIV85_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBY2962711.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            9756..10982
                     /locus_tag="MIV85_003403"
     CDS             9756..10982
                     /locus_tag="MIV85_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBY2962712.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(11121..12308)
                     /locus_tag="MIV85_003404"
     CDS             complement(11121..12308)
                     /locus_tag="MIV85_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBY2962713.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
BASE COUNT         4652 a         1575 c         1982 g         4134 t
ORIGIN      
        1 tttgatgaaa gcagaaaaaa caagtatata tccaattatt aaaaataatt taaacaaaat
       61 atcaattgtt gaatataaaa agggtcaaag atttgtagca tcagataaag acttacaaga
      121 agtgttcttt ataatagagg gagttgcatt agtggagtgt actactagag gaggaaataa
      181 atttcttgtt gacattgtac ctgaaaatga atttataggc aaaattagtt acatatatga
      241 acataatttg aaatgtgata tatttgcaaa gactaatata aaattatttc gatttgaaaa
      301 aaatgtattt gaagagtttt atctcaaacc agattttatt gcactatttc acagaaaatg
      361 tacaagaaga atatatgaat tatataaaac cagaatggta agagaactat tttcttgcac
      421 agaagttatt gcctattgta tatcaaataa acaagaaaat aatgtctgca atataaaagc
      481 tattcgtaat ttcagtgaaa tctattcaat tagtagaaaa agtagatacc attctctgct
      541 aaagttaact gaaaaggaga tagtaaaaaa aatgggtaat acatatgaaa ttttaaacta
      601 tgatgaatta cataaattgg catttgaagt aaaagaattt ttggaagatg agtaaaaatt
      661 gttacttaat caaaataaag tataataatt tctgtaaaaa atagaaatag tctcactgaa
      721 aatcaaaaat actttagtta ttttcaatga gactgtttag aaatattgta tacttataat
      781 gtatagtata attattaatc aatttccttt actatattaa tagcccattt tttagataat
      841 gctctaggaa caccaaatat aaacttaacc acttcttcac tataagtgag caaaacgagt
      901 acaaatatag gtgcaccttt aaatgcagct ataaaagtta gaggaataga agctaaccac
      961 atacatccta attctaaaaa tagagcatat ttagtatctc ctccacttct taaaatacca
     1021 attataacca atgtattaaa agatttaaga gccattagta ttcccattat aaagaatatc
     1081 ttagttatat cagaagctaa gctatcagaa acactaaaca tttttaataa taatggtata
     1141 tttaaaatta aaataattcc aagtattaaa ccagctgaaa atacaagtat agaaaacttt
     1201 ttagcatatt caatggctct tttaatatgg tcagctccaa gttcatttcc aagcataata
     1261 gatgcaccag atgcaataca tacagctgtc attatgaaga aattacctgt actggttgct
     1321 atctggctag ctgctatagc agaagtacca gctcttgcat atgcaacaga atacaggaca
     1381 gttccaattg cccatacaga gtcatttaca aatataggaa agctttttga tgaaaaagat
     1441 tttataaaaa ttttatcaat agcttttaga ttttttagac caaactttaa tatatagtct
     1501 tttttataaa ggtaaacata agtaatcatt aaaattaatt cacatattct agcaataaca
     1561 gtagctagag cagcaccttt tacacccaat gcaggaagac cgaagttacc aaatataaat
     1621 ccataattta aaataacatt tgttacaagt gcaaatgcac tacaaatcat acctaactta
     1681 ggatttctaa cacctcttga accagtacta aatacagtac ttacagcaat taatggataa
     1741 ctaaatactg caatactaaa gtaatctata caaagtttta ccacctcaga atcatacgaa
     1801 aatatgtgta taattggctt tggtgttagt aaagcaggaa taacaaatac aaaacttaaa
     1861 acaattgcca atacacaagt aagacctgtg acttttctta tattactcac atccttcttt
     1921 ccataaaact gtgaaataaa aactccagca cctcctgtga taccagataa ggacatatta
     1981 aaaagaaaga aaaattggtt tgcaactcca actgaagcta cagatgtttc ccccaaacta
     2041 cttatcataa ttgtatctat tacatttaca gaagtagaaa ttaagttctg tatgataata
     2101 ggtatacata aagatagaag tattttataa aatcttttat tttcgtcttt taaagaaaat
     2161 agttcttgca aataatcctc tcctttttac ataaattctt cccactcatc atatagagag
     2221 gcaaggttat tttctaaatt aattttttct tggctaactt ctttagcttt atctggatta
     2281 gagtatactt cttcttgaca taaaagtata tctaattttt caatttcaat ctctaacttt
     2341 tcaatttctt tttctatatt ttgtcttttt attctatttt tcttttctat ttctctttgt
     2401 tctctctctt ttcttttttc atcttttatt tgagttctag ttttttcttc tttttcttct
     2461 ataatactca tctcttggat ttgccttttt ttatctatat aataatcata atttcccaga
     2521 tattcagtaa ttccattttc atctaaaact aaaattttat caacaacagt atttagaaag
     2581 tatctatcat gtgatattgt aaatatagtc ccatcataat tagttaaggc ctcttcaagg
     2641 acttccttag aatcaatatc taggtgatta gtaggctcat ctaataacaa taagtttgca
     2701 tttgatagta taagtttaag tatggcaact ctagctcttt ctccaccact caatgtagaa
     2761 atcttcttaa aaacttcttc atctacaaat aaaaatgccc ctaacatatt tctcaaagta
     2821 gtttgagtaa gatgagtatt attttcccaa atctcatcaa ttattgtgtt atctaaatta
     2881 agagtttttt gttcctgatg gaagtaggaa acatgtacat tagttccaaa tttaatattg
     2941 ccactaagag gttgtagttc attagttatt attttaaata atgtagattt gccaacacca
     3001 tttgcaccta taagtgcaac tttttcccct ctatatatat ctaaatccaa gtctttaaaa
     3061 agtattcttt ctccataacc catagataca tctctaattt gaagaacatc attaccactc
     3121 tggacagaag gcgtaaattg tatacgagct tttttcctat aagcttctgg tttatctaaa
     3181 acatctactt tgtctaatgc tttttcttta cttcttgcac gctttaggtg tttttctcta
     3241 ccataagctt ttagtctttc aattgattct tcttgctttt ttatttcttt ttgttggtct
     3301 tcaaatttct taagctctag ttctttttct attttagata actcaacaaa tttagagtag
     3361 ttaccattat atactttaag ctttttattg tgaacttcaa aaattctatt tacggattgg
     3421 tctaagaaat atctatcatg agatattaac atgacagtcc ctttatattg ttttaaaaat
     3481 acttctaacc attctattgc ttcagagtct aagtggttag taggttcatc aagtaacaat
     3541 agagttggtt tcttaagaag taattttcct aaaagaactc tagttttttc accaccagaa
     3601 agtatgctta ttggcttatc catatcattg tcactaaatc ctaatccctt tagaactcct
     3661 ttggcttcag atttatatcc atatccattt aaatctgaaa ataattctag tttatgtgaa
     3721 tattcatcca tgattttttc tataattgga gagtttgttt ttgtactttc ttcagatatt
     3781 ttaacctcca attctcttaa ataggattcc atttctatca aatttttaaa aacttctagt
     3841 acttcttcca aaatagtatt atccgaataa aaattggtat tttgttctaa atatccgatt
     3901 tcacaatctt tagaagtgta aatatctcca ctatcatatc cataaattcc tgaaattatt
     3961 ttaaataaag tagtttttcc agtaccatta acaccgatta taccaatttt atcgccttca
     4021 tttactgtaa aactaatatt ttctaatata gaatctatac caaaactttt atttaagtta
     4081 ttacatgaca aaacaatcat aaatttctac ctccttgaac tatctaaaat tataatgttt
     4141 tgatataata taatcaaggt tatatgtatt agttttgaaa aagaaatatt ttattgtgaa
     4201 tcaaacaaaa aagaggacac ttttaggagg tgaagatgtt gggaaataaa aatatatcaa
     4261 tggcagttat aagaaggctc ccaaaatatc atagatatct tggagactta ttagataggg
     4321 atatacaaag aatatcttct aaagaattga gtgatataat agggtttacc gcttctcaaa
     4381 taagacaaga tttaaacaac tttggtggat ttggacaaca aggatatggt tataatgtag
     4441 aagctcttca tactgagata ggtaaaattc ttgggttgga tcgaccatac aacgcagttc
     4501 ttgtaggagc aggtaactta ggacaagcta tagccaatta tgcaggattt agaaaagctg
     4561 gattcgagat aaaagcttta tttgatgcaa atcctagaat gataggttta aagataagag
     4621 agtttgaagt attagattca gatactttag aagactttat aaaaaacaat aatatagata
     4681 ttgctgtatt atgtatacct aaaaatggag cacaagaagt tattaataga gttgtaaaag
     4741 ctggaatcaa aggtgtatgg aattttgcac ctttagattt agaagttccg aaaggtgtta
     4801 tagttgaaaa tgtaaactta acagaaagtt tatttacctt atcgtattta atgaaagaag
     4861 gaaagtagac aacttaaaca tattaataat gagcagttgt aaagagtatt gagaaagtca
     4921 gaagatttaa tattaaatcc tctggctttt tgaaatatta ggataaaaat ttaaataatg
     4981 tatggaaata aacaatatta aggagagtgg tttttgtgga ggaattatgg aaaaaggcaa
     5041 ttgaatttca tggtcatgaa tgtccagggt tagctatagg atttaaagca gcacttgcag
     5101 caaaaaaata tttaggatgt aaacagtcag gagatgagga aattgtatgt atttctgaaa
     5161 atgatgcttg tggaatagat ggtatacaag tagtgctaag ttgcacaatg ggtaagggaa
     5221 atttactact taggatgact ggaaaatcag tatatcattt ctttaataga gaaaatggaa
     5281 aatctataag gatatatgta aagtcaaaac catttgagat ggatagagaa ggatacaaaa
     5341 gatatttatt agaaagtgat tttgaagaaa tatttgagat tacagatact aagttaagac
     5401 ttcctgaaaa agcaagaata tttaaatccc ttaaatgtga agtgtgtggt gaatttgcat
     5461 ctgagcaata tataaggatt gaagaaggaa agaaagtatg tcttgattgt tttgataaat
     5521 atgaaagatt ttatgaagag tattaaaatt ataaattaga ttaaagttaa aagtattaga
     5581 tatgtgctaa cagtatttta agatgaatta ggtagcaaca taataaagta tataaataat
     5641 attaattgaa tcatacataa ttaaaaagag gctgattagt atttataaaa taaaatcagt
     5701 ctctttatga ataacgaatt attattctgg ttgaggtgca tctacaggac aagctcctgc
     5761 acaagaacca cagtctatac aagaaccagc atctataaca tatgcgtcgt ctccagctga
     5821 tatacagcta acagggcatt cagcctcaca agcaccacag cttatacaag cgtcagtaat
     5881 tttatatgcc attttgaaat cctccctttt atatgtattg taattcaata acattataac
     5941 aaatattatt gaatataaca attaaattaa ttctacaaca aaaactttat tatgatattc
     6001 ttgttttaaa gttttacaat aaagtttaat ctgcttatat ttttatttat tttaaagaag
     6061 tttattttaa aaataaaatt aaatttaaaa agttatgtat tgattatatt taaaaatgtt
     6121 atactctaaa aaagtatatt ttatttaaaa atttattaat acaaaggaga tttactatga
     6181 aaaataaatt agtttacata tgtattatga gtctattgct atttgtagta ggatgttcta
     6241 ataatccaaa taaggaaagt accattaaaa aagactctaa gaataaccaa agccaagtta
     6301 aagaagaaaa aagagaacct gtgaaaaaag atataactat aagtttcgct ggtgatgtaa
     6361 ctatggggaa ctataaaggt tcatcatatt atggcagttt tgaccatgaa tttaaaagac
     6421 aaggagaaga ttacaattat tttcttaaaa atgtaaaacc tgtatttgaa aaagatgact
     6481 taacagtggt taatttagaa ggtccactta ctacagcgtc aaatgcaaaa gaaaaaaaat
     6541 ttgcatttaa aggaaagcct ggatatgtaa atattttaaa atctggaagt gtagaggcag
     6601 taagtattgc aaataatcat tcagaagatt attttgaaga aggaatgaaa gatacacagt
     6661 ttatattgga cgagaataaa ataaattatt ttggattagg gaaagatgct gttgtagatg
     6721 tcaaaggaat taaagtgggt ctattagggt ataatggatt atcaactgaa tataatgaaa
     6781 aaaatttaaa acaaatggaa gatgatatta agtccttaaa aaagaaatcg gatgttgttg
     6841 tagtgtactt tcattggggg atagaattag attattatcc agataaaaaa caaaaagatt
     6901 ttgctcatta tgctatagac aagggagcag atttagttat ggggtctcac ccacatgtga
     6961 ttcaaggaat agaaaagtat aaaaataagt atatagctta tagtctaggg aatttttgct
     7021 ttggaggaaa taagaatcct tctgatacag atagttatat atatcaacaa acctttactt
     7081 tttcagataa taaattaact tcaattaaag agccaaatat aataccaact tcaataacat
     7141 ctagtaactc cagaaataat tatcaaccaa aaatattgga tggaagtgag aaggatagag
     7201 ttttaaataa acttgaaaaa ataagcaaag atttaaataa ataaaatgta aaaaaaaata
     7261 aatatatata tttattttaa taatttatat tttgtttagg gtatggtaaa tcgtggtatt
     7321 aaataagtag attttaatag ttaaattata gtcaattata ataaagctat ttaatctact
     7381 tttttaatat aaaaatataa gggggaattt gtaatggctt gtaacacttg taaaatgtgc
     7441 gaaagtgcag acaagaaatt agaaagtttt gtagcttcaa aggatgttga aacagcattt
     7501 catagaacag aagatcagaa agttaagtgt ggttttggac ttcagggggt ttgttgtaga
     7561 ctctgttcaa atggaccatg tagagtaact cctaaatcac caagaggtat atgtggagca
     7621 gatgcagaca ctatagtagc aagaaacttt ttaagagcag tagcatcagg agcagcttgt
     7681 tatttacatg tggtagaaaa tacagctaag aatttaaaaa atgttggaat aactaaaggt
     7741 gttgttaaag gagaaaaaac attaaatcaa ttagcagaga tgtttggaat agaaagtgat
     7801 gaaaagtatg ataaatgtat aaaggttgca gacaaagtta tcaacgattt gtataaatca
     7861 agagatgata aaatggaatt agtagaaaaa atagcttatg cacctagagt gaaaaagtgg
     7921 aaagagttag gtataatgcc tggtggtgca aagtcagaag tttttgatgc aatagtaaaa
     7981 tcatcaacaa atttaaacag tgacccagta gacatgctag ttaattgttt gaacttaggt
     8041 atatcaacag gattatatgg tcttacacta actaatcttt taaatgatgt tatgttggga
     8101 gaaccagtta taagaatggc tcctgtagga tttaatgtaa tagacccaga ctacataaat
     8161 ataatgataa caggtcatca acattcaaca tttgcaaatt tccaagatag attaaaagat
     8221 gaagatgtta taaaattagc tcaatctgtt ggcgcaaaag gatttaagtt agtaggatgt
     8281 acatgtgttg gtcaagattt acaattaaga ggagaacatt atcaagaagt atttgctgga
     8341 catgcaggta acaattttac aagtgaggct gttttatcaa ctggagcaat agatatagtt
     8401 ctttcagaat ttaactgtac tataccaggg cttgaaccaa tagcagataa atataaagta
     8461 aaaatggttt gtttagatga tgttgctaaa aaagcgaatg cagaatgcat aggtttagac
     8521 agaagtaaat tagatgaact tagtaacact ttaatagaaa aagcattgga gtcttataag
     8581 gagagaagag gaagtattga aatagatata ccaaaagacc atggatttga acaatctttg
     8641 actggtgtaa gtgaaaagaa cttgaaagcg tttttaggag attcatggaa acctcttatt
     8701 aatttaattg cagaaggaaa aattaaaggt gttgcagctg ttgtaggatg ttcaaatatg
     8761 acagcaggag gacatgatgt aaatactgtt gaacttacta aagaattgat taaaaaagat
     8821 ataatagtac tatctgcagg atgttctact ggaggattag aaaatgttgg tcttatgtca
     8881 cctggagcag aagaattggc aggagaaaac ttaaaagaag tatgtaagac tttaggaata
     8941 ccaccagtat taaactttgg accatgtcta gctataggaa gactagaaat agtagcaaca
     9001 gaattagcag ctgaacttgg aattgaccta ccacaattac cattagtgct ttcagctcca
     9061 caatggttgg aagaacaagc attagctgat ggagcttttg gtcttgccct tggcttacct
     9121 cttcatttag ctttacctcc atttataaca ggaggaaaat tggtaacaga agtattaaca
     9181 gaaaaattaa aagacttaac aggaggacat gttatagtga atccagaccc taaatcttca
     9241 gctaatcaat tagaagaaat aataatagat agaagaaaaa atttagggtt aaaggatgtg
     9301 gaatgcaatg catagaattt ttataaataa agatttatgt acaggatgta agagctgtgt
     9361 actagcatgt atgctaaaac acaataaaga ttatgacatg tacactcttg atttagaaaa
     9421 tatagataat gatagtagag ggcatataga attagatagt agacataata atccagttcc
     9481 aattctttgt agacactgtg atgaacctga atgtgtatta gcatgtatga gtggtgcaat
     9541 gcataaagat agtgaaagtg gaatcgtttc atatgatgaa gagaaatgtg gttcatgtta
     9601 tatgtgtgta atgtcttgtc catatggatt attaaagcca gatgatagaa gcaagcagaa
     9661 catacttaaa tgtgatttat gtaaagatga ggagtatcct agatgtgtag ctaattgccc
     9721 aagtggagca attgaattac agaaggagga aaatgatgaa ttatgtagtg ttaggggcta
     9781 gtgcagctgg tataaatgca gtaaaaacat taagagaatt agataaagat tcaaatatag
     9841 tagtaatttc taaagatgaa aacgtatatt caagatgtat gttgcatcac gttatatctg
     9901 aacacagaac tttaaaacaa ataaattttg ttgatgaaga ttttatggag caaaataatg
     9961 taaaatggat tgcaggtaag actgttaaag gtatagacat aaataaaaag gtagttcaga
    10021 cagaagacat tactgtaaat tatgataaac ttttaatagc tacaggtgca tcttctgcta
    10081 ttcctcctat aaaaaattta agagatggaa attttgtata ttctgtgaga aacatagatg
    10141 atatttataa aataaaagaa aaagcacaaa attctaaaaa tgtagttata ataggtgctg
    10201 gtttagttgg tatagatgca ttagtgggat tatttaaata tgagcagtta aatatttctg
    10261 tagcttttat ggaaaagtac attttagata gacaattgga tgaatataca gcatcagtgt
    10321 atgaaaataa gttcaaagaa aaaggtgtaa aattttaccc aagtgcatca atacaagaaa
    10381 ttgtattgga taacagtaaa aatgttacag gtgttgcatt ttcaaatggt gaagttttag
    10441 atgcagacat ggtaattgta gctacagggg ttaaaccaaa tgctgacttt ttagatggaa
    10501 caggaataga atatgataga ggtataataa tagatgatat gtgccaaaca acacaaaaag
    10561 acatatatgc agcaggagat gttgtaggta aaaatgctat ttggcctctg gcagtaaagc
    10621 aaggaattgt agctgcctat aatatggttg gaaaagataa gaagatagaa gatgaatttg
    10681 cttttaaaaa tagtatgaat ttcatggata taccaactat ttctatagga atgaatacac
    10741 ctgtagatga tagctataaa gtattaacca gacatggaat taatgattat aaaaagtttg
    10801 tttttaaaga taatgtaatc tatggagcag ttatacaagg agatatttca tatgtaggtg
    10861 tattaactta tttaataaaa aataaagttg aaatatatga tttagaaaat aggatatttg
    10921 atatatgtta tgcagacttt tttaatataa aagaaaatgg agaattttgt tatagtgtat
    10981 agtatatacg tggagtaagg tttataaata cagtaaatca ataaatagag ttattctaaa
    11041 ataagaaaaa tgacaaatct tatttagaaa tagctctatt ttttgtaatt aaatttaaat
    11101 tatattcaat ttgtaaaata ttattttgaa caattataca tatactctct agttagaggt
    11161 aaatcatttt ttataccttt agtgaaaagt atttgatgta tatctataat accagtgttg
    11221 aaagcagcag cacaagaaca aaggtataaa tcccacattc ttataaactt atcatcaaac
    11281 atttctttaa tctttggaag attctcagag aaattttttt gccagtatag taaggttttt
    11341 acataatgta atcttaaact ttctacgtct atagtatgat atttgtaatc actacaaata
    11401 tgtatcattt ctcttaggct aggaataact cctcctggga aaatatattt ttttatccaa
    11461 gggtctccat aagattcctg caatccactt atatagtgaa gtaaaaacaa tccaccatct
    11521 tttaaaacag catttacgtt tttaatgaaa agttcatagt tttctctacc aacatgttca
    11581 agcatcccaa cgcttacaac tctatcaaac ataaggtctg atttttttaa ttctctatag
    11641 tccataagtc ttacctcaag atagtcttga aggttctctt ctttaattct tgcgttaaat
    11701 tccttaaatt gctcttcgct aagtgtaatt ccaacgccgt gaattttata tttttttgca
    11761 gcttctatta gtaaaaatcc ccaaccacaa ccaatatcga gaaggctcat accttcctct
    11821 aaatttagtt tagttaatat gtggtgaact ttattgactt gagcatcata aagagtatca
    11881 ttatcatttc taaagtatgc acaagaataa ctaagtgtct tatctaacca taagctataa
    11941 aaatcgttgc caatgtcata gtgggcatgt atttctttct tttgatgtct cattgaattt
    12001 gatgagtgca atagatgttt tacagctgaa ttatcaatat tgaatttgtc tatttgtttt
    12061 aaaagtagat ttaaagttaa gaataaatct ccctcaactt caatgtctct atttatgtag
    12121 gcttctccaa gtgctaaaga tgtacttttt aatagttcag acttgctaat atcattattt
    12181 actataactt tgaactgagg ggagccctct ccaattagaa attcttcctc atctttaagc
    12241 ctaactagaa atggtgtttc accaaatttc tctaaatagt cttttaaaaa attttttgta
    12301 atattcatat taccagctcc ttctaatgta aatccagtaa gtt
//
LOCUS       DAGQVA010000105        12315 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.105, whole genome shotgun sequence.
ACCESSION   DAGQVA010000105 DAGQVA010000000
VERSION     DAGQVA010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.105"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(356..2140)
                     /locus_tag="MIV85_003405"
                     /pseudo
     CDS             complement(356..2140)
                     /locus_tag="MIV85_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
     gene            complement(2924..3112)
                     /locus_tag="MIV85_003406"
     CDS             complement(2924..3112)
                     /locus_tag="MIV85_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962714.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            complement(3138..4277)
                     /locus_tag="MIV85_003407"
     CDS             complement(3138..4277)
                     /locus_tag="MIV85_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBY2962715.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSLNSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(4814..5653)
                     /locus_tag="MIV85_003408"
     CDS             complement(4814..5653)
                     /locus_tag="MIV85_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBY2962716.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YISGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(5677..6435)
                     /locus_tag="MIV85_003409"
     CDS             complement(5677..6435)
                     /locus_tag="MIV85_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBY2962717.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6482..6955)
                     /locus_tag="MIV85_003410"
     CDS             complement(6482..6955)
                     /locus_tag="MIV85_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBY2962718.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(6984..7400)
                     /locus_tag="MIV85_003411"
     CDS             complement(6984..7400)
                     /locus_tag="MIV85_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBY2962719.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(7447..8499)
                     /locus_tag="MIV85_003412"
     CDS             complement(7447..8499)
                     /locus_tag="MIV85_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBY2962720.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKVIAVDVFDEKLDLAKGLGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            8895..9575
                     /locus_tag="MIV85_003413"
     CDS             8895..9575
                     /locus_tag="MIV85_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBY2962721.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9708..10028)
                     /gene="sugE"
                     /locus_tag="MIV85_003414"
     CDS             complement(9708..10028)
                     /gene="sugE"
                     /locus_tag="MIV85_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBY2962722.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            10410..11237
                     /locus_tag="MIV85_003415"
     CDS             10410..11237
                     /locus_tag="MIV85_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBY2962723.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            12058..>12315
                     /locus_tag="MIV85_003416"
     CDS             12058..>12315
                     /locus_tag="MIV85_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBY2962724.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTD"
BASE COUNT         4041 a         2095 c         1401 g         4778 t
ORIGIN      
        1 ctgcttgtat ttccccatct gttgatttgg ctggtactac tacatctatt tctcctgtat
       61 ctgctgtttt accacttgat tcttgtgtta ctgtaaatac caatgttact gtttcctctg
      121 tatttggagg tattattgtt ccatcttcct ttataacacc cttattgctt gatgttttta
      181 ttgctatagt atatccactt gatactgatg gcatagttaa tttagttgca tcttttgctg
      241 gtgcaggaac gcttgttatt tttgccactt cattgtctaa tgctgcttgt aattcttcat
      301 ctgttgattt agctggtact gttacagata gttcttttgt atctgctgtt ttaccacttg
      361 atgtatgtgt taccgtaaat actaatttta ctgttgttgc tgtatttgga ggtattattg
      421 ttccatcttt ttttataaca ctctcattac ttgatgtttt tattgctata gtatatccac
      481 ttgatactga tggcatagtt aatctagttg catcttttgc tggtgtaggc acgcttgtta
      541 tttttgctgc ttcattattt actgatgttt gattagaaga acttcctcct gaagatgagc
      601 ctcctccatg tgaagaacct ccacttgatg aacttcctcc tgaagagtta gaacttggac
      661 tatttccact tattgttgga gaattatctc ccttaacact acttattgta cctttattat
      721 ctatagtagt ccctttagaa ttatttgtaa ctgtagttat cttaccacca ttagtcactt
      781 ttacttgact tgctccagat gctactgtta aactaccaat ctcaccttta gaattatttt
      841 ctatcttggc tccattttta tcattaacct ttaagttagt tatttttcca taattaacaa
      901 aagttccatc ttttacatca tctataacta catcatccac ttttgcatag ttatttacat
      961 caccattagg catgttgata gtcacagtct ttgtatatgt accatttaag tttactgtta
     1021 ctgccttatc agtttgtatt gtaaatgctt ctttaacctc actagttggc ttaaagttta
     1081 taacatcatt agcagtagct ttatctatag ctgattttaa ttcagaaatt gttttagctt
     1141 caactgtttt tacttcttgt aatgacttca tttcattaaa tgctgtctca ttaccattcc
     1201 caccaacttt agttatctta tcaaaactct tagagttaac tagagatttt tgtgaagctg
     1261 ataagttctt tccaactaaa actactggtg attgattttt agcacctaat acacctactg
     1321 ctagtgcatc tataagttgg tcttgtttat tcataccatc tttagttaca taagcatttt
     1381 ttaaatctgt ctttttataa aattctttta ttacttttgc atttgtatca tttctatctg
     1441 ttccacctag tcttgtacta tttggtagtt tatttttaac agcttcagaa attgaactct
     1501 ctccacctac tacataagat tgagttattc cagcatcttt tataaatttg tctgcaactg
     1561 ctgttccatt tttagaatca gcaagtatta ctggcatatt gttttgtgca gctggtgctc
     1621 ctacacttac agcatctgca agtccttttt caccattaac tacagctatt ttcttaacat
     1681 cacttatagc atctaatttc tttgctaatt ctaaggatgt ttgatatctc tcagctccag
     1741 agattctctc aaaagatatt tttaaatttt ttatttcttt ttctatattt gtacttaata
     1801 cagaagttcc acctattaag tatacttttt tagcttttaa tctttgtatt tctgctttcg
     1861 tcttatcatt taatttatct ttacttgtta aaagtattgg agcatttttt gcttttgcaa
     1921 atggtgttgc agatagagca tctgctatag atgagtcgtt tacgattact acctcatcag
     1981 catttttcca tccatcttga cttattttaa cagcagtttc atatctttct tgccctgtta
     2041 aatttgttgc cacagtttgt gcactagcta tgcctgctgt tgaacttcca gctatcattg
     2101 taactgtaag cattgcagca atcttctttg gtattttcat tttattttct tcccccttgt
     2161 ccatttgata ttacttaatt ttttaacttt gttcccgttc taattctaaa ggatacttaa
     2221 tatctaattt taaagaggtt tctaactata atgatttcat aattaatttg taattatttt
     2281 gttacattgc agtcattatg taaggaataa agaaattttc ttattgattg aaaaatttgt
     2341 aaatttatat tttaaggtaa gtttgatttt tatgttaatg aattgttata aaaaataggg
     2401 ttttgtataa aaaaagtagc ctttagaatt aaaagtgcta ctctttttac aaataaattt
     2461 tattatttat acttgtaatt atatattaaa taaccaattt tatccatatg aaaaacaaat
     2521 aattgcgata tttttttaat tattctttat atttacattt taattcaaat tacttttata
     2581 aagattatat ctgttgcata tactacttta agtgctaata tatctccccc tcaattagaa
     2641 tcttcgttat ctcaatagac gttttctact gtcaaagtta ccaacatttg aaacttatta
     2701 aatttttata taaaaaagac ctagaatata aattccaagt cattttttat taaatttatt
     2761 ttttacaata taatattgtc atgattaaag aacacaaatc atacacaaat tggtcataaa
     2821 tcttacataa atcatctaca aaaaatacat tatttatatt aaatctatat aactaaatta
     2881 agagcatatt gtacaatatg ctcttagaaa agatatttct tgtttatagt ttatagtatt
     2941 tctctatgat ttttattttt atcatttcaa aaataaaaat taagattaca gttattatca
     3001 tattttgtgt actattttct ataatattat aatgaaacaa tgaaaaaaca ataattaatg
     3061 aaattacgtt tatagcccca gaaatcaaaa atgccttttt cttattattc atatattccc
     3121 tctccagatt atctaaatta gtctatatca agcattttta agtacttatc attaacttta
     3181 tatatatttt tttctttaga caaaatctct atctcttcaa gattattaaa cacttccatc
     3241 aactggtcaa ctaattcaat ttcctttatt ccagccttta agtatctact tttattcttt
     3301 tttatataat tttctaatgt catagaatag ttatctttat tgcaaatata ttttaatata
     3361 tgttcttctg ttgctgatag agttatgtca ttttcaaaca attcttcttt taatatactt
     3421 tctaaagatt ttctatcatg catattacgc atctcattaa tagattgtat tatagacttg
     3481 agcataaatt ctataaatac agttaaatta tttcctttgt tttctacatc aagtatagcc
     3541 ttataatact tagttctgtt tttagatatc atatatgata ttgaaaaatc cttgaaagta
     3601 tcatatcctt tatcaatcaa atatagatat gataaggctc ttgatgttct tccattacca
     3661 tcactaaaag gatgaacata tacaaagtaa aaatgaatta tagcactttt aattaaatta
     3721 cttactttgc tattttccat aaaatctatt aatttactca taaagtcata tatcttcaaa
     3781 ggttcaagcc ctgtatgtat aatctcacct tttgaatcac atacatatac tttttcagtt
     3841 ctatactcat attcttctga atccaagcag ttttcgccca atatatgatg caaatcatat
     3901 ataaatttgt gactatataa tttatctaag ttgtctaatc catattctaa ggctctatga
     3961 ttattgtaaa tcatatattc acttttatta cttggtttca tctttcctct aattatagat
     4021 tttgcaatct ttctagttga aaaagcacct tctattacac tagaataata agactctagt
     4081 gccaaatcat ttttatcttc tattgtttta aatatcttac ttgatgttaa tttatctatt
     4141 tcatttatta aatttaatat attttcagtt tcatgatagt atagttcttt attatcaaaa
     4201 ctatttagag aaagtacgat tttatttcca gtaaagtatt tgtttttgta ttcttctatt
     4261 gtcagtttaa tcaccacctt agattatctt tatctattaa tattaacaaa aagtattaat
     4321 ttttacacta tttttgatta tttgttttat aattatcaaa ctcaatttag tgttaaagca
     4381 taataaattt taataaataa tgcaaaaatt taagaataag catttaaaat atatgtcaca
     4441 ggaagtttac aactattatt tataatacat tagttatata ttataatatc tcgacaatgt
     4501 cttaacaata tctcgattat atattttaat atgtaactaa tatattataa tattttaatt
     4561 aaattaaata aatttatatt tttttgaaat tacttaatat tttatataaa aatgaaaaag
     4621 cacctcattc tgattaaaaa tctttctgag atacttttta aaatattaaa tactacatat
     4681 agcttacata agtttaaaat ttaatctatt ataaaattac cctaattgcc aaacttttta
     4741 atataaattt tccaacatcc tacaaatata atcaatagat atagaatcct aacttacacc
     4801 aatatatatt tatttaaaat agtcctaaaa tacctgtaat agctcccact actatcagta
     4861 taaacattat ttttattgga gaaagacctt tttttaaagc aaagagtact aataaagtaa
     4921 gtaccaaagg aattaatcct ggaaatatct tatcaagtaa atccgtttga agactaaatt
     4981 taaaatcacc actaatataa cttattggtg tagataaatt gataaaccta cctacaagcc
     5041 cccccatgac taaggtacct agtatagaag ccccttctat aaccttattt actattccac
     5101 cttgaagtat actttcaaca gcttttttcc catacttata tccatttgtc cacattccaa
     5161 aagaaattga agtcattatt atatattgag ctattacaaa taatataggt cctgcaattg
     5221 atgctcctcc ctcagttaaa ccaatacaaa cagccaacac tataggagtt ataactcctt
     5281 gagttaaagt atctccaatt cctgctagtg gacccatcaa gcctgttttg atagcattca
     5341 taccatctcc acttatttca tctgctccat tagctttttc ttcttccata gctattgtta
     5401 ttccatgtat aacacatcca catataggtt ctgtgttaaa aaatgctaga tgagtctcca
     5461 cttcttgttt taactcttcc ttatctggat ataatttttt aagtactggc aacattgaat
     5521 gtgaaaaagc tgttgattgc aatctttcat aattgtaatt agattgtgca aagaaaaacc
     5581 atcttaacca tgattttatt acatctttct tgcttaacgt tttcttagat acttcatttt
     5641 ttatatctga cataatattt tccccctcac atgtatttaa gatgtagcac tatcttttcc
     5701 gtacttaatt gaagtaattg taagagcaag tattactcca ataacagata ttactattat
     5761 atctacttta aaataaacag ccattagtat tcctaatatg aaaaaaggca tagtaaattt
     5821 gtttccaatc aattttaaat tcatagcaat cccaagtgct ggcaacatag ccccaattac
     5881 attaaataca tgtaacacat tatcattcat tacttccaac ataccatcta tcgcatttgg
     5941 accaaaataa acaactaata atgctggtat aaaactcatt gcaaataaca gtatctgtgg
     6001 tggtactata tttataaatg ctactctatc aacattccct ttttgaacct ctctatcagc
     6061 ccaatgtgca aaaaaagaat ttactgtcat ctttccaatc caaagtacag ttgcaacagt
     6121 tcccaatggt acagctattg ccattgcagt acttacatct agcttagatg ctatagctaa
     6181 agcagtacct acatatcctg caaaagctgg gtcccccatc tgagctcccc ctgctgatat
     6241 aaaacctaga tatatcatat ttatacctgc tcctataatt gctccttgaa cagggtctcc
     6301 taatataatt cccgttacaa atccagccaa tagaggtcta ttccatgtaa aaaatccaac
     6361 ataagtcaac cacggactcc aagaaagata ataaaaaatt gctattaata ctgcttgaat
     6421 tagtgaaatg tgcatattct tcctccctat tttcttttaa agatttacaa gatagtcttc
     6481 tttacaataa tgttcctaca tcaattttct ttgcatctgg tactatttgt ataaagcatt
     6541 taacatcttt tgatattagc tctctaaata tttctttttc ttcatctgac acagatatat
     6601 ttttataaaa actttttcta ccaagccctg ctcccatacc tccaacattc aattccttta
     6661 aatctacccc gctatttact aaacctaaga cagttttagg gtatttgacc aatactatta
     6721 aattttcatc tccattatgt gattttaaga cttcagcacc tgattctaca tcatgtactt
     6781 caaccttaac agttgatgga gctgccattt gtaaaacttg aactataaat gggtccttta
     6841 ctactaaatc atccacgatt actatccttt ttgccgatgt aatcttacac caagcagtaa
     6901 taacttgccc atgtattaat ctatcatcaa ttcttgttaa tgctatatta ctcataacta
     6961 ttcctccaga tttttaattt attttacaac tttaaaacag ttttaacatc tttgattcct
     7021 gatatcccaa cttcctcaca taaattcttc aagtctttta acttcatagt atctctgttt
     7081 aaaaataact ctaaaagcat aggtaaattt acacctgtca aacattctaa ctcacatacc
     7141 ttagcaaatt tatttattat aatagcagat gtattaaatg gagttccgcc ataaaaatca
     7201 agcaatacta aaaccccttc atccttatat ttctcaattc catcttctaa ctttctacta
     7261 aactcatcta tgctgtcacc atggtttaat cctaaagttt ctacattttc ctgtttgcct
     7321 actattaatt cagcactttc taacattgct ttagccatat ttccatgtgt ggctataatt
     7381 attcctgcca tatgaatcat acctttctta acctttttta tatggattat tatttagtac
     7441 tctaatctaa ttatctatat taatcattat cttaccaaag aaaatatccc ttttgtatac
     7501 tttttcaaaa taagctggta cttcttctaa atttattcta tgtgttacta atttttcaac
     7561 attcatatca cccttttgca tatgatacaa tccagcactc cattcttttc ctgggaatgg
     7621 aaaggagttt ccaaaccaag ttccctttac agttaattca cttcttacta tcttttcaaa
     7681 ttgctctcta gtcaaagcta catccccata tggtacacct gcatacaata ctgtacctcc
     7741 ctttttagct agcaacagta cttgaccaca tgtcagtgga gtaccagccg attcaataac
     7801 aatatctgca ccatctccat cagttaacct ttttatttct tctacaatat tcttttcttt
     7861 tgcatttata caaatatctg cccctaaccc ttttgccaag tctaacttct catcaaatac
     7921 atccacagct attacttttg tagaaccaaa tatttttgcc cattgtattg aaaataatcc
     7981 tattggacct gtaccaagta ctacaacagt atctccaact ttagcttctg acctaaaaag
     8041 accatgtcct gctatacata ctggttctag cgcagcggca gtctcataac ttatctcatc
     8101 tggtattttt attaaatttc tctctttcac ctttgtatac tctgcaaaac aacctccaag
     8161 ttctttattt cctattattg ctacattatt acatcttgag tacaagcctt ttttacattc
     8221 atcacattca aaacatggca tagctggaca aacagcaact ctatctccta ttttaaaact
     8281 ccttacttct ttaccaacct gtgccacttc tccagaaaat tcatgcccta aaatttctcc
     8341 aaccatatgt ggacctgtct ttgaatattt tgatatatca gaaccacata ttccagctac
     8401 ttttacttta attattacat catctttttc taatattttt ggtacatcca catcctccac
     8461 tcttgtgtct cttataccat agaatctaac tgacttcact attaaccacc cctacttttt
     8521 atttgagaat atatccctat tgtttatatg ttaaatatct aaagcaactt tcatgccaat
     8581 atatgtaagc attgtattca tgcattttat aaaattatca ttaaatgtgt gtcaaagtgt
     8641 gtcaaaagtt tcttatatta aaacttatgt gtgtcaatat aaacaacact aacattttat
     8701 attagttctc ttattataag ttttataaaa tgtacttttt ttgttatttt tataaaattg
     8761 ttcggaaatt tcccttctat ttgtgatata atattaaata taaggtatca atataaattt
     8821 tcatgcgaat atcagaactt ttttgacact aatgccttat tcaatataat aatttaactt
     8881 tttggaggtt gtttatgaaa aaagtgtatc aaggaaagac taaagatgtt tttgaattag
     8941 ataatggaaa ttacttactt aaatttaaag acgatgtaac tggtaaagat ggagtatttg
     9001 acccaggcga aaatagtgta ggtctaagta tagatggaat tggtagagct aatttagaga
     9061 catctgttaa gttctttgaa attctaaaca atgctggaat taaaactcat tatgtaagtg
     9121 ctaatttaga agaagcaact atggaagttc taccagcaaa agtttttggt aatggattag
     9181 aagttatttg tcgttataga gctgtaggta gtttcttacg tcgttatggt tcatgtgttg
     9241 aagaaggtgc taaactagat tgttacgtag aagcaacttt aaaagatgat gaccgttgtg
     9301 accctcttat aacatctgaa ggtttagaag ctttaaacat tatgactcaa gctcaatttg
     9361 attcaatgaa aagcatgact caaaaaattt ctaacatagt tcgtgatact atagctgaaa
     9421 aaggtcttga gctttatgat attaaatttg aatttggatt ctacaatgat gaagtaatct
     9481 taatagatga aatagcatct ggaaatatgc gtgtttataa agatggtgta atagttgacc
     9541 ctatggattt aactgctctt ttattagata aatagtatat acatataatt tacaaatata
     9601 ataaacttat aaataagata agctatgaag taaagacttt ttaaatgttg attattttta
     9661 aacattttct cgcctttaat ttcatagctt atttaaatta atatactcta attagtagat
     9721 aatagcttta accctacaat tcccaccaca ataaaaccta tacatgcaat tcttgatata
     9781 ctaataggct catttaaaat agccatgcct acaatagctg taccgacggt accaattcca
     9841 gtccatattg catatgaagt tccaagtgga agatgtttta gtgctaatga caaaaaataa
     9901 aaacttacaa tcattccaac aacagtaagt atacttggag tcaatttaga aaatccatgt
     9961 gaatttttta gttgaaaagc ccaaaacact tcaaacaaac ctgcaacaaa caaaaataac
    10021 catttcataa attcatccct cttttcaaat atgtctctta tttttccaat aaaataacct
    10081 gagaaatatt ataaaatatc tcccaggttt ttgtccttcc gtgttcacaa caaaaactat
    10141 gttgtgggtt ttatcttgga ccagaccaat cattaataat tgcggaaccc tataaaactc
    10201 tattaattat tctattttat ctataataat actatcaaca tatataaaaa aagtcaatat
    10261 atgggttcca tctataataa aaataacttt tatatacctt ttaatattct tattcacttc
    10321 tctccatacc catttgggtc aatctaagaa tatctaattt ttatttaata tgttataata
    10381 acataaaaat attgaaagga gtaatttcta tgaatttcta taaaattgca gtatgtcaga
    10441 tgattactac agaaaataaa attgaaaata tcaatcatgc tgtagatatg gtaacagaag
    10501 ctgccatcaa tggagctaaa attgtagttt tgccagaaat gtttaactgc ccatatgaaa
    10561 ataaatattt tcctaaattt gctgaagaat atccaggtga aacaacaacg atattaagta
    10621 aattagctga gaaacatgga atttatctag tttctggtag tattcctgag ttagaagatg
    10681 gaaaaatcta taatacttgc tatgtatttg ataaaaatgg agctctaatt ggaaaacatc
    10741 gtaaaatgca cttatttgac attgaagtta caggaaaagt tagttttaaa gaatcagata
    10801 ctcttacagc tggaaatgat gtcactgtaa tagataccga atatggaaaa gttggtatag
    10861 ctatttgcta tgatattcgt ttccctgagt tatcacgttt aatggctctt aaaggtgctg
    10921 aaatcgttat cttacctgct gcatttaata tgactactgg tcccgcccat tgggagttat
    10981 ctataagaat gcgtgcttta gataatcaga tattctatgt tggtgctgca cctgctagaa
    11041 atatgaatgc ttcttatata gcttttggaa attcaagaat ttcagaccct tggggaagaa
    11101 taattgctca agctgatgaa aaagaatgta ttatttatgc tgacattgat agagatttaa
    11161 ttcctgacat aagacaacag ttaccacttc ttaagcacag aagaactgat ttatatgaac
    11221 ttaatacttt gaaataaaac agaacataac cccataaatc gtaaattaag tgttaaaaaa
    11281 atttatgggg ttctcattaa tttgatttaa aattaatttc ataaaaataa tgctaaaatt
    11341 aatttaatta aataatacta ataattacta atgattatgc taattatcag catttactaa
    11401 ttaatcacta ttagttattt cttttattaa atatctttac ttttttactt attatgtctt
    11461 ctagctttat atttggatta tggtatttct ttctattttt agtcacatct ttctattgaa
    11521 ttacttgctt aaaacaccaa tgcacacatg ccagataatg ttcacaatta tgtagaaatc
    11581 ttgctctacc ttcttcaatg ttgatattat ctctcctagt tgatattatc tttcctaaaa
    11641 tttcttttaa ttaaaaaaca acattagttg atatatcaag tatattttaa gcaactgaaa
    11701 aaaacaataa taattgatat atcaactaat taatgtagat taattcattt ttataattta
    11761 tatacttttt aattaatcta ccttatttaa ttaaaatcct tcctttctat ttatccattt
    11821 tcaacttaaa ttataagatt tcatcagcta tatttttgca taccaataat tattaaatat
    11881 caaatatata ttctattaaa atttctaata atttcatcct tgatttattt aatatataaa
    11941 aatatactaa ctttaatgat taagttttga aatataacta aaaatttgag aatttattga
    12001 gatttttata ctaaaatata catactatac aaacttaatt tagaagggag cattcttatg
    12061 aacaataaaa tactcgtcgt agatgatgag gaaggtataa taacactctt aaaagattac
    12121 tttgaaatga atggttatga ggtttacact gctcaaagtg gaaaagacgc attaaaaaaa
    12181 atatccaaaa atccagatat cattctactt gatataaaca tgcctgaaat agatggaatt
    12241 gaagtttgta atagaattag agattatgta tcatgcccta ttctatttct tacagctaga
    12301 attgaaaata ctgac
//
LOCUS       DAGQVA010000106        11937 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.106, whole genome shotgun sequence.
ACCESSION   DAGQVA010000106 DAGQVA010000000
VERSION     DAGQVA010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11937
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.106"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..282
                     /locus_tag="MIV85_003417"
     CDS             <1..282
                     /locus_tag="MIV85_003417"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962725.1"
                     /translation="IQLLNITENDSFDAVSGKEESKSNSNNNVKQSNRILTDKQLTRL
                     YAIANSVGVNKALLKEQVFKQLGKDIKDLNKSEYDAVCAAYEKQAFKGA"
     gene            1059..1157
                     /locus_tag="MIV85_003418"
                     /pseudo
     CDS             1059..1157
                     /locus_tag="MIV85_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
     gene            1227..1478
                     /locus_tag="MIV85_003419"
     CDS             1227..1478
                     /locus_tag="MIV85_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962726.1"
                     /translation="MIIIRSQDRLDLMRVNRVEIGFNQVYAILENDIRKIGEYESIER
                     AMQVLNDIQKFIENGVRTDYIDSCRVRHNQEKVFEMPFE"
     gene            1496..1852
                     /locus_tag="MIV85_003420"
     CDS             1496..1852
                     /locus_tag="MIV85_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962727.1"
                     /translation="MAKVWVDAGTFLERTKDIEDMFEFNLRKVRDRNKKINVIDLRVN
                     NEGQGRKGKKVECFNIVTGETKVFNTAVEASKYVYFTDVYIAHLARTGKVSKNGWKAR
                     YIQEVTDGIGKCGTSN"
     gene            1821..1970
                     /locus_tag="MIV85_003421"
     CDS             1821..1970
                     /locus_tag="MIV85_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962728.1"
                     /translation="MVLANVEQVIKLAEKILNKKKCSVNKAIDIVIKILSKYECEGML
                     RNEFN"
     gene            1957..2406
                     /locus_tag="MIV85_003422"
     CDS             1957..2406
                     /locus_tag="MIV85_003422"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962729.1"
                     /translation="MSLIKYRGYDFENEKWIYSATIMWSNILECLVMLTEGCKWQKVS
                     NVGVCSGEWARNNQEICEGDILKGYDNFHDTSQYGVVKRDIGSIKLYLEWHYLKKLEG
                     EWIELINKTEIYHSRDYKIVGNEYENLEEVRTEFLERKESLENEYLS"
     gene            2509..2685
                     /locus_tag="MIV85_003423"
     CDS             2509..2685
                     /locus_tag="MIV85_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962730.1"
                     /translation="MDDRLEMINASVNYIQMICESSNIAIIAERGRVRILDLETKEKY
                     DLLKNKLEEMLEEI"
     gene            2795..3868
                     /locus_tag="MIV85_003424"
     CDS             2795..3868
                     /locus_tag="MIV85_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBY2962731.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFRGERSSLFFTVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLVELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFIVGHFRGRSTRKVFPIERKSGKNLEQLNNPTHSTNRIYDAVGIARCIRSQAGG
                     GGAKTGLYFIDLNKNSKVTINARCLKAKYNAGVTNRNCDNSGVLVNAVLTPDRVNKRQ
                     NGRRIKESGEPMFTLTAQDKHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDS
                     QLYKQAGNAVTANVVYEIAKRMG"
     gene            3947..4168
                     /locus_tag="MIV85_003425"
     CDS             3947..4168
                     /locus_tag="MIV85_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962732.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKQKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMTEYYCDGGIEI"
     gene            4165..5169
                     /locus_tag="MIV85_003426"
     CDS             4165..5169
                     /locus_tag="MIV85_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBY2962733.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDMDLFFQKKIKTVSR
                     AKDIRTAVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNKSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDEYHLRVLDKDAEKEEANSKFITEFLNATKVKDDKYKTKMFKSTAENWITNAL
                     GNDIKQAEDVRSILNYTLKEKHEIDINNFVDKTIKDDKLKDSFKEHMEEKGLVEGFSI
                     DKKWVDKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIVIKNVTFYEEK
                     "
     gene            5251..5580
                     /locus_tag="MIV85_003427"
     CDS             5251..5580
                     /locus_tag="MIV85_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962734.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNDTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            5617..5988
                     /locus_tag="MIV85_003428"
     CDS             5617..5988
                     /locus_tag="MIV85_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962735.1"
                     /translation="MFNIYKVKIKTKRTLEQVRNQSVDFEYSEKGLKNTLKYYNLIDD
                     LKVIVVKFGDEYCLANYNEEDRKIIMEAHYLLEQDEYTGCYINEYERFKKDWENGNCD
                     GEACMVFSDDEIEIIEKLREG"
     gene            5991..6131
                     /locus_tag="MIV85_003429"
     CDS             5991..6131
                     /locus_tag="MIV85_003429"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962736.1"
                     /translation="MNKRIKMKKRLIHKKCDERCVNYDFVISNNLITCNVCRMQIQRK
                     YG"
     gene            6246..6587
                     /locus_tag="MIV85_003430"
     CDS             6246..6587
                     /locus_tag="MIV85_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HBY2962737.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYE
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEALEEELTK
                     INSHLELEDLR"
     gene            6713..7120
                     /locus_tag="MIV85_003431"
     CDS             6713..7120
                     /locus_tag="MIV85_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBY2962738.1"
                     /translation="MKVFLVIDGEPVGKERPRFNLATKRTYTPQKTKDYEELIKWLYQ
                     SKVRHYFTGYIKMTLRCYYSIAKSNSKKIKEQKRNNVLRPNKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDVI"
     gene            7222..8070
                     /locus_tag="MIV85_003432"
     CDS             7222..8070
                     /locus_tag="MIV85_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBY2962739.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRESRQINELINKNRKRFKDGKDILDLLGVGLDDTKIKELGFTQQSINSYRGLKNKG
                     LLSGIYILSERGYAKLLKILEDDIAWELYEKLVDGYFSMRKELNNPLLSASKELQAIF
                     MLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKAYK
                     NKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNSYKLPIVFEEEIRLLNS
                     QLSIVS"
     gene            8213..8701
                     /locus_tag="MIV85_003433"
     CDS             8213..8701
                     /locus_tag="MIV85_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962740.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSTVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            9448..9621
                     /locus_tag="MIV85_003434"
     CDS             9448..9621
                     /locus_tag="MIV85_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962741.1"
                     /translation="MATKSILKNVDVRKKAFGRNLVSALENAKNKQEKEVVLSKKCSE
                     VPKDKIKDIFGRF"
     gene            9621..10232
                     /locus_tag="MIV85_003435"
     CDS             9621..10232
                     /locus_tag="MIV85_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBY2962742.1"
                     /translation="MSGYLIVNLSNMLGELEEEEVKKILSSFSCPLNKDVEEFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIVGYFTLANKYFTIKRKTLSNSLARKIVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            10309..10497
                     /locus_tag="MIV85_003436"
     CDS             10309..10497
                     /locus_tag="MIV85_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962743.1"
                     /translation="MEIKKNTQDVVSERKNSLDSEFKIPASGVCYMAEFIKESREIIK
                     ELDKHFESCLDVLSKARL"
     gene            complement(10477..10794)
                     /locus_tag="MIV85_003437"
     CDS             complement(10477..10794)
                     /locus_tag="MIV85_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962744.1"
                     /translation="MSKNIDIRNLKQFQKKIERMEQNLKPDFDKIRTIILSKKFMNQH
                     TNFDSFDELLAFGNYIVNSEEDFLAIPDNEFDLFIVKNTDFPDWQTMLDSAYSKYLES
                     CLR"
     gene            10918..11145
                     /locus_tag="MIV85_003438"
     CDS             10918..11145
                     /locus_tag="MIV85_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962745.1"
                     /translation="MGFEISGNLNFDSVIDDLKKEVENNPTIFTSQNVGNKFKEKCKI
                     CEKISEFEILEDGKVKCLECGTEFELNLKVE"
     gene            11215..11907
                     /locus_tag="MIV85_003439"
     CDS             11215..11907
                     /locus_tag="MIV85_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962746.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISSKYDISLNTLKSWIKRYNWASE
                     KKKGAPINKRGAPFSNKNSVGHGAPKENKNAEKFGFFSKYLPEETRELIQEISIKDKF
                     DILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDEL
                     KISVDYGDRNDS"
BASE COUNT         4955 a         1157 c         2314 g         3511 t
ORIGIN      
        1 attcagttac taaatataac tgaaaatgat agttttgacg cagtaagtgg aaaagaggaa
       61 tctaaaagca attctaataa caatgttaaa caaagtaaca gaatattgac tgataaacaa
      121 ctaactagat tatatgcaat agctaatagt gttggagtta ataaagcatt attaaaagaa
      181 caggttttta aacagctagg aaaagatata aaggatttaa ataagagtga atatgatgct
      241 gtttgtgcag catatgagaa acaagccttt aagggtgcat aacaggaggt gatagagtgg
      301 cagttttcag acagatatat acaagctttt ggactgaccc aaaggtacaa gaggagtgga
      361 caccagaaga taaatttttc tttatacttc ttcttagtaa tcctcaaaca acacaaatag
      421 gagtttacca agtaactaaa aaacaactag cattttggat ggggtactca gaagaaagta
      481 taagagcatt aatggataga ttcgtaaatc accataagtg tattaaatat aatcccgata
      541 ctagagaaat tgccataaaa aactggggca aatataactt aactaaaggt ggtaaaccaa
      601 ttatagattt acttaataaa gaactcaaag aagttaaaga tattgagtta ataaaatatg
      661 taattccatc aatagaaaaa tcagatataa gaaaaatatt tgaggattat tacgaaatgg
      721 ctaaaaatgg ggattcttac gatacgtcga cgatacgtga acgagtcgta ccacgatacg
      781 gggacaataa caataagaat aacaataaga ataacaataa gaataacaac aacaataagg
      841 atgattcggt ggttgtggat aaaataaaac aatactttga tttagaatct aaagacattg
      901 aaaaaattgt tgatatattc atacatacag gaagaggaat tgactattta gaggaaaaac
      961 taaggttggt aaaaaataca gatggagtaa aaagtattac aggctatctc ataaaagcat
     1021 tagaagaaga ttataagcct ataccaagta gaaaaaataa gactaagttt cataatttta
     1081 acgagacatt tactaagtat acgtctgatg aactagacga gattattaaa aagagtcaaa
     1141 aagagaagtt cagttgaatt aaatagtcta gggagtagtt atacaatatt acttcctagg
     1201 agttaaaaaa tattggaggg atagaaatga taataattag aagtcaagat agattagatt
     1261 taatgagagt taatagagtt gaaataggtt ttaatcaagt gtatgcaata cttgaaaatg
     1321 atattagaaa aataggtgaa tatgaaagta ttgaaagagc tatgcaagtg ttaaatgata
     1381 tacagaagtt tattgaaaat ggagtaagaa cagattatat agattcttgt agagttagac
     1441 ataatcaaga gaaagtattt gaaatgccat ttgaataaaa aggggggaac taaatatggc
     1501 taaggtttgg gtggatgcag gaacattttt agaaagaact aaggatatag aagatatgtt
     1561 tgaatttaat ctaagaaaag taagagatag aaataaaaaa ataaatgtaa ttgatttgcg
     1621 tgtaaataat gaggggcaag gaagaaaagg taaaaaagta gagtgtttta atattgtgac
     1681 tggagaaact aaagtattta atactgctgt tgaagcaagt aaatacgtat attttacaga
     1741 tgtttatatt gctcatttag caagaacagg taaggtttct aaaaatggat ggaaagctag
     1801 atatattcaa gaggtgacag atggtattgg caaatgtgga acaagtaatt aagttagctg
     1861 aaaagatatt aaataagaaa aagtgttctg ttaataaagc tattgatata gttataaaaa
     1921 tattaagtaa atatgagtgc gaggggatgt taagaaatga gtttaattaa gtatagaggt
     1981 tatgattttg agaacgaaaa gtggatttat tcagcaacaa taatgtggag caatatactt
     2041 gaatgtttag ttatgttgac agagggttgc aaatggcaga aagtctctaa tgttggggta
     2101 tgctctggag aatgggctag aaacaatcaa gaaatttgtg agggggatat attgaaagga
     2161 tatgataatt tccatgacac aagccaatat ggagttgtaa aaagggatat tggtagtatt
     2221 aagttatatt tggaatggca ttatttaaag aaacttgaag gagaatggat agagcttata
     2281 aataaaacag aaatatatca tagcagagat tacaaaatag ttggtaatga atatgagaac
     2341 ttagaggaag tcagaacaga gttcttagaa cgtaaggaga gtcttgagaa tgaatatctt
     2401 agctagtgcg atattagtaa taggaagttt tatagctggt agagtttatg agtatagatt
     2461 gaatctaaaa gagtgtgaaa attgcgacaa taaaagaggt gtataagaat ggatgataga
     2521 ttagaaatga taaatgcttc tgtaaattat atacagatga tatgtgaaag ttcaaatata
     2581 gctattatag cagagcgagg aagagttaga atattagatt tagaaactaa agaaaaatat
     2641 gatttattaa aaaataaact cgaggaaatg ttagaagaaa tataagtgaa aatatctaat
     2701 taagacagtt tagagagtta caaaatatct tttagtataa attattgttg aagtgttttg
     2761 tgactctcaa aaatgaaaat aaggaggcgt tgtattgctt acatttttag atttattcgc
     2821 agggataggt ggctttaggc tagggatgga aaaagcagga cataaatgtt tgggacattg
     2881 cgaatatgat aaattcgcaa atttaagtta taatgccatg cacaaaccga aggaggatga
     2941 atggtttgaa agagatatta gagaaattag aacagaaaat atcccaagag cagatgtctg
     3001 gtgttttgga ttcccatgtc aagacatttc tgttgcaggg aaacaatttg gattcagagg
     3061 agaacgttca agtttatttt ttacagttac aaaacttatt agagaactca aagaagaaga
     3121 tagacccaag tatttactta ttgaaaacgt taaaaatcta cttagtgtta atggaggatt
     3181 tgatttcctc aaagttctcg ttgaactgga tgaaatcggc tatgatgcag agtggcaagt
     3241 tcttaattct aaaaacttcg gagtacccca aaatagagaa cgaatattca ttgttggaca
     3301 ttttagagga cgaagtacac gaaaagtatt tcctatcgaa agaaaaagtg gaaaaaatct
     3361 tgagcaacta aataatccaa ctcatagtac aaatagaatt tatgatgcag ttggaattgc
     3421 tagatgtatt agaagtcagg caggaggtgg aggtgctaaa acaggtctat actttataga
     3481 cttaaataaa aactctaaag taacaataaa tgctagatgc cttaaagcaa aatataatgc
     3541 aggtgtgaca aatagaaatt gtgataatag tggagtttta gttaatgcag ttttaacgcc
     3601 cgatagggta aataaaagac aaaatggtcg tagaattaaa gaaagcggag aaccaatgtt
     3661 cacactaaca gctcaagata aacatggaat tttgaaaaat ggagatataa gaaggttaac
     3721 accaaaggaa tgctttaggt tgcaaggatt tccggataaa tattacgaaa gagcagcaag
     3781 tgtatgctca gatagtcaac tgtacaaaca agcgggaaat gctgttactg caaatgttgt
     3841 atatgaaata gcaaaaagaa tgggctaaga gttgcaaaat gtcttttagt atgagtattg
     3901 ttgaagtgtt ttgtaactct caaaaatgaa aataaggggt gaataaatgt caaagtatgt
     3961 gcttagatgg caaaaagggt tattgttgga tgaacgtaag ataaattatt cttgtggaag
     4021 taaggaaatg ttaaaacaaa aagcagaatt attagctaaa gatgacaaga tactgcttgt
     4081 aacaatagat aaagttgaag aagttataaa ggatactaga agtcaaaaaa tgactgaata
     4141 ttattgtgat ggaggaattg aaatatgata atacacaaat ttataataca tgttttagat
     4201 aagaatagcg atacaccaat actaaatgac tttgagggta gggttagtca agatatggat
     4261 ctattttttc agaagaagat taagacagta tcaagagcta aagacattag aacagcagta
     4321 tttaatgact atagtaacaa tttaattaag aagtgttgcg aacaaattat ttatgatgaa
     4381 agttcatttt taaataactc taaagagatt gcagcttatt tatttgatgt tatgaaattg
     4441 aatgctacat tagaatcttg cgacttagca atttgtttat actctcaaaa agatgaaaag
     4501 aaagttgcta tattaaagct tgattacaac aagtcatata ctcattcaat cgagtttaaa
     4561 gatgataaat ttaatataca aatgtctaaa aatgaaatta atatacaaga gactaagaca
     4621 gtaaaaattg ctgctttggt tggtttgagt ggaatgaatg acgaatatca tcttagggtt
     4681 ttagacaagg atgcagaaaa ggaagaagct aattctaagt ttattacaga gtttctaaat
     4741 gctactaaag tgaaagatga caagtacaag actaagatgt ttaaaagtac agccgaaaat
     4801 tggataacta atgctcttgg aaatgatata aaacaggcag aagatgtaag aagtatatta
     4861 aattatactt tgaaagaaaa gcatgaaatt gatataaata attttgttga taaaacaatt
     4921 aaagatgata agttaaaaga tagttttaaa gaacatatgg aagaaaaagg tcttgttgaa
     4981 ggatttagta tagataaaaa atgggttgat aaaaagctta aaaagagaaa tataaaaact
     5041 gacaatggct ttgaaataaa aggtaactta actgattttg aggacccaat gaaatataca
     5101 gtaagacaaa atcaaaatgg gtctatagat atagttatta agaatgtaac attttatgag
     5161 gaaaagtagg tactcatgtg actattggct agagaaggag aagtaaataa taagaggatg
     5221 taaatttaaa ctagttagga ggaataactt atgaagattt ttttattgac tatactgcta
     5281 ataattattt gtatattagc aaattatgtg aaaaatcgca tatataaaaa atctataaat
     5341 aatctaaaat ataaatattc tgtaggggaa aagattatat atcatcaaat aaactgttac
     5401 tataacagaa tggttggttg tgaaatttta gaaaaatgtt atagtacgaa atttagaaaa
     5461 agaaataccc cgctttataa agtaaaagca tatgtaggtg ataacgatac aacatgggtt
     5521 ataccagagt ggagaattga atgtcttgct acgacttatg gagaatttcc taaatattaa
     5581 ataataaaaa ttggctggag aaggagattg taaattatgt ttaacatcta taaagtgaaa
     5641 ataaagacta aaagaacatt ggagcaggta agaaatcaaa gcgtagactt tgagtattca
     5701 gaaaaaggat taaaaaatac tctgaaatac tataacttga ttgatgattt aaaagtaata
     5761 gtagttaaat ttggagatga atattgtcta gctaattaca atgaagaaga tagaaaaata
     5821 ataatggaag cacattatct tttagagcag gatgaatata ctggatgtta tataaatgaa
     5881 tatgaacgat ttaaaaaaga ttgggaaaat ggtaattgtg atggggaagc ctgtatggta
     5941 ttttcagatg atgaaattga gataattgag aagctaaggg agggttaaat atgaataaaa
     6001 gaattaaaat gaaaaaaaga ttaattcata aaaagtgtga tgaaagatgt gtcaactatg
     6061 actttgtaat tagcaataac cttataactt gtaatgtgtg taggatgcaa atacaaagaa
     6121 aatatggata aagtatgtga agagaactat aagaaattaa gaagtaaata gaataaaata
     6181 gtcaaggtaa gtttgtgaat gaaactagaa tgttataggc ttgacttata aaaggagtgc
     6241 gttaaatggc taatatatat tgtgaaaatt ataattgtaa aaactacttt gaagatatgt
     6301 gtatgcttga aagaattgaa attaataact tcaaagaatg cgaaagctat cttgaaggta
     6361 aaaatgagct atatgaatta gaaaacggat atactataca tcctaaagat ttgaaaatgg
     6421 tgaaaagtaa agattattct gttgaagtta ctcatattcc aactggtatt acagtaaaat
     6481 gccgttctac aaatagtatt ttaaaaaata aaaataagtg tttggaagct ctagaagaag
     6541 aactaacaaa aataaactct cacttagagc tagaagattt acgctaaata ggaagtgagc
     6601 ttatgaaacg aagaagatgc agttggtgtg gtaagttatt ttatcttgaa gaaaaatcta
     6661 aggatgttta ttgttgtaaa gaatgtagga agaaggctaa gaaggtgaaa aaatgaaagt
     6721 ttttcttgta atagatggag aaccagttgg taaagaaaga cctagattta acttggctac
     6781 taaaaggacc tatacaccac agaaaactaa ggactatgaa gaattaataa aatggttata
     6841 tcaatctaaa gttagacatt attttactgg atacataaaa atgactttaa gatgttatta
     6901 ctctatagca aaaagtaaca gtaaaaagat taaagagcag aaaagaaata atgtgttaag
     6961 acccaataaa aaaccagata ttgataatgt ggtcaagatt atagctgatt cactcaatga
     7021 gatagcttat aaagatgata cgcagattgt tgaggttgta gctagtaaat attacagtga
     7081 taaaccaaga gttgaggtta tattagaaga tgttatttaa ccaacggaaa aatccgttcg
     7141 ttagattagg tactcagttt ttcataaaaa tgtgaaaaag ctgaatagag aatatatcaa
     7201 atggtaaagg agagataaat tatgaatgaa aatataaata aagaaataac agtacttgga
     7261 actttagaaa tcgagggaat gaaatttcat aacattgagg gtggatttgg agaacataag
     7321 aaagcaatgc tagtaaaaga tatagctgag atacataata gagaatctag acagattaat
     7381 gagcttataa ataagaatag aaaaagattt aaagatggaa aagatatatt agatttgtta
     7441 ggtgtcggtt tggacgatac caaaataaaa gaattaggat ttactcaaca atcaattaat
     7501 tcttatagag ggttaaaaaa caaagggtta ttatctggga tttatatatt atctgaaaga
     7561 ggttatgcaa aattattaaa aatattagaa gatgatatag cttgggaatt atatgagaag
     7621 ttagttgatg gatatttctc tatgagaaaa gaactaaata atcctctttt aagtgcatca
     7681 aaggagttac aagctatatt tatgctagat aagaaacaag aagtcttaga aactaaaata
     7741 gagaatgtta atgagaagtt agagaacttt atggatgatg caccattatt caatatcgag
     7801 tgtgagtgta ttgttaaaga ggttaagaga gtagcaacaa aatcacttgg tggacatgga
     7861 agtaaggctt ataaaaataa atctttaaga ggtaaagttt atagtgatat ataccatcag
     7921 attaaacgag aatttggagt agatagttat aaggctataa agcgttgtca attagataaa
     7981 gtattagaga ttgtaaatag ttataagtta cctatagtgt ttgaagaaga aataagactt
     8041 ttgaatagtc aattatcaat tgtgagttaa gacaggaata gatttttctc ctttaaaggg
     8101 gaaaacctgc aatagttaat taaaagagaa aaggagtgct ttcacactcc acttgtcaaa
     8161 aatataaaac ttttatccaa gattattata acataaacag gagtgtggaa gtatggataa
     8221 taatatcaat aaaaaagaac tatttaaaaa agtagaaggt agattacatc attataaatt
     8281 tttaagtgca gaaattaaga atcttgaatt agatatagaa agtagagaaa atgagatatt
     8341 tgggtgtaag gctgttggat atgatgaaaa agtaagtcca acatatgctt ttaattcaac
     8401 tgttgagaat gagattataa aaaaagaaag agatattact agattgaaaa aactgaaaaa
     8461 agataaagaa atagaaaaga agaaaataga aaatgcactt acatgcttag atataagaga
     8521 agaacatttt tttaaactgt tttataatag tagaatgaaa aatagtatgg tttatatatc
     8581 cttagagatg aactcagata ggaaaacatg tagatgtgta agggaaagat tagtgtataa
     8641 agttatggat atgctttatc caagaattaa ggaaaatgaa ctcccattat ttaaaaatta
     8701 gaaaattccc cagtttttcc ccagaaattc ccactttatt ccctactttc tccccttttt
     8761 gattaaaaaa gcatgagata atagtattgt ggaaataaag atttccctct caaaacttaa
     8821 tatttgacta gggtataagg gattgcccta gtcactacga acagactagg cagggcgtga
     8881 ggacgctgtt agttcaattc taactatgtt caaatattaa tcaacgtata cactaaaagt
     8941 agagaaattg agggcaaaat tttatatttt gtatcttaat tcagaagtct aaaaatcggg
     9001 tggggcttgg taacctcact caccatgcag gtactggtgt ctagtctaag ttcgattctt
     9061 agaacctgcg acataatata tgtatctccc tactaaaaat gctaagttta ctccaaactt
     9121 agcattttaa tttttaaaaa gaaaaaagaa atttttattg tcataatact atttgtttag
     9181 gtatattata atgtgcatac ttaaaattaa atacttagca agcatttgaa ttaatataca
     9241 taagatatat gacataattt tttatagtgt aagttattta aattaattat aaataacagt
     9301 aattttatta tataaaatgt acatattgtg aataataata ataaaatcat gtacaaaatg
     9361 ccaactgata attcctcgaa atatattgca tatttaacgt aacgtcagta taattaaatt
     9421 ataatagtga agtggaaggt ggtacttatg gctacaaaaa gtattttaaa aaatgtagat
     9481 gtaagaaaaa aggcatttgg aagaaatcta gtatcagctc tagaaaatgc taaaaataaa
     9541 caagaaaaag aagttgtatt aagtaaaaaa tgttcagaag taccaaaaga taaaataaag
     9601 gatatattcg ggagatttta atgagtggct atttaattgt aaacttaagt aatatgctag
     9661 gagagctgga ggaagaagaa gttaaaaaaa ttctctccag tttttcttgt ccccttaata
     9721 aagatgtaga agaattttta aaaaacaaag ctattgaatt ttctaaacag ggtttggcta
     9781 gtacacattt agtgctaact tcttataaag gcaagcctgt tatagttgga tatttcactc
     9841 tagctaataa gtattttaca ataaaaagaa aaacattatc aaactcttta gctaggaaaa
     9901 tagtgaagtt tggacaatac aatgaagaac taagaagata tattattgga gcacctttga
     9961 tagggcaaat aggaaagaat tattcaaata attataataa attaatcaag ggtgatgaac
    10021 ttctaaaaat tgcatgtgac aagataaaag cagtacagtt agatatgggt gggaaaatag
    10081 tgtaccttga atgtgaagat aaacctaaat taattgaatt ttataaggat aatggatttg
    10141 tagactttgg aaaaagaagc cttgataaag acgaaacaga ttcgttagat ggggactatt
    10201 tagttcaaat gttgaaatat ctaaaaaaat aaaagtacat aaaatctaaa atgactatct
    10261 tgatagatgg tcttttttta tacaataaat taaaaggaga atgaaattat ggagattaag
    10321 aaaaacacac aagatgtagt atcagaaaga aaaaattccc tagattctga attcaagata
    10381 cctgcaagtg gtgtgtgtta tatggctgag tttataaagg aatctaggga aatcataaaa
    10441 gaattagata aacattttga aagttgtcta gatgttttat ctaaggcaag actctaaata
    10501 ttttgaatat gctgaatcaa gcatggtttg ccaatctggg aaatcagtat ttttaactat
    10561 aaataaatca aattcattat caggaatagc taaaaagtct tcttctgaat tgactatgta
    10621 attaccaaat gcaagtagtt catcaaaaga atcaaaatta gtgtgttggt tcataaattt
    10681 cttgctaaga attattgtgc gaatcttatc aaagtcaggt tttaaatttt gttccattct
    10741 ttcaattttc ttttgaaatt gctttaaatt tctaatgtca atatttttac tcataagaac
    10801 acctcctttc aatagaatat tagcataaaa ttgtggtgaa ttctgctatt gtcgaacgat
    10861 tgttgaagga tattgtataa taacatagaa tttactatac tataaggagg tgattatgtg
    10921 ggatttgaga taagtggtaa tttgaatttt gacagtgtta ttgatgattt aaaaaaagaa
    10981 gttgaaaata accctactat atttacatca caaaatgttg gaaataagtt caaagaaaaa
    11041 tgtaaaatat gcgaaaaaat atctgaattt gaaatactag aagatggtaa agttaaatgt
    11101 ttagaatgtg ggactgaatt tgaattgaat cttaaagtag agtaaacaaa aaaagaatct
    11161 caattatgag gttctttttt tattcccaaa acaaacaaat aaagaggtgg tgatgtgcaa
    11221 gatgtcaaag aaaaggtaaa acaagattac ttaaaaggaa tgaaacaaaa ggaaatatca
    11281 tcaaagtatg acattagctt aaacacttta aagtcatgga taaaaagata caactgggct
    11341 agtgaaaaaa agaagggtgc acctataaat aaaagaggtg cacccttttc taataaaaat
    11401 tcagttggtc atggtgctcc aaaagagaat aagaacgctg aaaagtttgg tttcttctca
    11461 aaatatctac ccgaagaaac tagggaattg atacaagaaa tatccataaa agataaattt
    11521 gatattcttt gggagcagat aacaatccaa tacgcagcaa taataagagc acaaaagata
    11581 atgtatgtta aagacaagga agaaatgatt aaagaattaa agaaacatga aagtacagaa
    11641 aatggagaga agatagagta tgaatttcaa tttgcatggg ataggcaagc atcttttctt
    11701 aatgcacaga gtagagctat gagtgaactt agaagtttaa ttaaacagta tgatgaaatg
    11761 attcataagg attggaattt ggctacagag gagcagaaaa caagagttga gaagttgaaa
    11821 tgtgaagttg ataacctaag taaagatgat attggagatg atgagttgaa aataagtgta
    11881 gattatggtg atagaaatga tagttagagt aaattttaat ccagatttca aggaagc
//
LOCUS       DAGQVA010000107        11781 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.107, whole genome shotgun sequence.
ACCESSION   DAGQVA010000107 DAGQVA010000000
VERSION     DAGQVA010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11781
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.107"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            36..1040
                     /locus_tag="MIV85_003440"
     CDS             36..1040
                     /locus_tag="MIV85_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2962747.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1166..2278
                     /locus_tag="MIV85_003441"
     CDS             1166..2278
                     /locus_tag="MIV85_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2962748.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATEYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2768..3529
                     /locus_tag="MIV85_003442"
     CDS             2768..3529
                     /locus_tag="MIV85_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962749.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3532..4350
                     /locus_tag="MIV85_003443"
     CDS             3532..4350
                     /locus_tag="MIV85_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBY2962750.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4530..5132
                     /locus_tag="MIV85_003444"
     CDS             4530..5132
                     /locus_tag="MIV85_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBY2962751.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    5591..5828
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5892..7811
                     /gene="thrS"
                     /locus_tag="MIV85_003445"
     CDS             5892..7811
                     /gene="thrS"
                     /locus_tag="MIV85_003445"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBY2962752.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            8579..9670
                     /locus_tag="MIV85_003446"
     CDS             8579..9670
                     /locus_tag="MIV85_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBY2962753.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            10340..11680
                     /locus_tag="MIV85_003447"
     CDS             10340..11680
                     /locus_tag="MIV85_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBY2962754.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCV
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         4763 a         1090 c         2066 g         3862 t
ORIGIN      
        1 taaaaatatc gtaaatgtat gaggagtgaa atttaatgcg tttcaaaaga atattgatat
       61 tgatgttaac tgtagcaatg atagctggaa tgttggttgg gtgtgctaat aacccaagca
      121 ataatcctag ctctagcaaa gataataaaa gtgatataag cgataaaagt aattcaaaaa
      181 aatctgtatc aatgatacta gatattgaag gaacaaataa tgaagctatg aataattcag
      241 ctttattagc attaaacaat gctcaaaaga aacttaatat agatacaaac aaagtggaat
      301 cagatgattc ctcaactttt tctaatagta tagatatttt atgtaatgac aattacgatt
      361 taattatagc tgtaggagct agatttgcaa aaccattgga gatggtagcc aagaaatatc
      421 caaagcaaca atttgcaatt atagactatg agtatgacaa gcaaccttct aatataactt
      481 caatttctta tgaagataat aaatctggat atctagctgg attaattgct ggaaaaatga
      541 ctgaaagcga taaggttggt tttataggag gaacaaagag ttctagtaga gataaatttg
      601 aatcaggttt tagagagggt gttaaatttt ctaatagtag tataaaggat atttcagttg
      661 agtatgcaga tgtttttaaa gatagcaaat cagtagaatc tatagctaaa aaaatgatgg
      721 ataatggagt ggatattatt ttttctacta ctgaagatga ttcaaaagct gtaatagatg
      781 cagtaagggc aaaaaataaa aaagttatag caacgaataa agaccaacat gagttagctc
      841 cagaaaatgt tataagttct attgtaaaag attttgagaa tcctacttat aatctgatac
      901 aaagttttgt aaaaggaaat tataaaggcg gaaaagttat agaaaacaca gttaagtctg
      961 gaagtactgg gcttgcccaa aatagttctc aaaatattcc tccagatgtg ttagaatatg
     1021 ttaataagaa caataaataa tctactataa tatccaagaa tacttatgac tttagttatg
     1081 aggtgaattg gatgttataa tagacatata tagaaagaca tatgcagagg taggtcagac
     1141 ctatctaaat cagggagtga attttgtgaa aataaaaagg atattgatgg cttgctttgt
     1201 agtagttttt acaattttta tattagctat atgtaatttt gattttgggt ttgataaagt
     1261 aaataagaat aattctaata tagatagtgc taaatcgaaa cagagtgagt ctaaaagttt
     1321 gccaacttca gcagaaaagg ataaatcaaa tagtaaaagt aagaataaag aagatgacac
     1381 agaagatgat tcatatgtaa gaaaaactat tggagtattg ttagataccg aaaacttaaa
     1441 taacgaatca tataataaca atgtactatc agccttaaaa agggctgacg aagattttga
     1501 tgttaggata aaacttgaaa aaccaaagac ttctaaaagt tttaaagaga gtatagaaaa
     1561 actgcataag tatgaaccag atttgataat agcagttgga gccagatttg cagagccaat
     1621 taaagaagct gctactgaat atcccaaaca gcaatttgca atagttgact atacttataa
     1681 agttcagcca gctaatgtaa tttctgtatc atttcaagat aatgttactg gatatttagc
     1741 aggacttatt gcaggtaaaa tgactgatac tgggaaggtt ggttttatag gaggagttga
     1801 gggttctagt agagataagt atgaatctgg atttagaaag gggcttaaaa cttcaaataa
     1861 agatgctgag ttactagtta agtattcaaa tatatttgaa aaccctgaat cagctagaac
     1921 tattgcaaag gaaatgagag attctgatag agatgttgta ttttcagcta cagaggatga
     1981 tagtaaaaga gctattcagg tagcaagaga aaatggaggt aaagttatag ctattaataa
     2041 agaccaatac gatatggctc cagataatgt aataagttca attataaaag atgtagaaca
     2101 acctgtatat gaactgataa agaacgttgc aaaagatggt tttaagggaa gtaaagtaat
     2161 ggaatttaaa ataaaagatg gagaacttgg cttgacttca aagagcagta gaaatatacc
     2221 accagatgtt ttggaataca taaaaaaaga gtataacaaa gtgaaagata catattaatt
     2281 attgatgtag aagattataa aaatatactg cttaagttta gattggtgat aaaaggatat
     2341 atttattaaa tttgtgctaa ctgtacaaaa tatattgatt aagtttagat tagtgataaa
     2401 aagatatatt tattaaattt gtgttaacag tatggaatat actgcttaag tttagattgg
     2461 tgataaaagg atatatttat taaatttagt ctaactgtac aaaatatatt gattgagttt
     2521 agattagcaa taaaaagata tatttattaa atttgtgcta actgtacgga atatactgct
     2581 taagtttaga ttagtgataa aaagatatat ttattaaatt tgaaccaact gtacaaagct
     2641 atactaatta agcttagatt aactatataa aattataaca ataagtgtgt gggcagaaaa
     2701 attctgctac acactttatt tatattcaca taaaaaattt atcaaaaaaa agaaaaagga
     2761 gtaaaaaatg gaatttacaa gagaaccatt tatactagat gacgatttgt gtctagcttt
     2821 ggtggacaaa agaattagtt atctaatgga aaatgaatta aaattaagaa atatagagat
     2881 aataaaaaca atagaatgta aagaattata tgaaagcata aaatatcacc cggatatatg
     2941 tatttgtaat ttaggaaaag gagatataat tgttgcgccg aatgtatata atcaatacaa
     3001 agagttatta agtagatata aatttaatat aattaaggga gaagctaatt tattaaatag
     3061 atacccttat gatatacctt acaatattgc gatagttggt gactatgcta tacacaattt
     3121 taagtatact gacaaagcaa tattagatta tattgaaaat aataaactta aaaagataaa
     3181 tatagagcag ggctattcta aatgctcaat ctgtatagta gatagaacgt ctataataac
     3241 atcagataaa ggtatttgga aaagtatgaa gaatacagaa atagagtgtt tattgataga
     3301 aaaaggtcac ataaatttat ttgagatgaa ttatggattt ataggtggat gtacagggtt
     3361 gatttctaag gataaactag ctttttgtgg agatgttaaa aaacatcctg actatgaacg
     3421 tataaaaagt tttgtagaaa gtaaaaacaa ggagatagtt acacttagct gtgaaaattt
     3481 actagatata ggttctatag ttcctctcat gacaagaaag gagcgataac tttggttgag
     3541 aaggataata tttcttccat gaaatttttg aggaataata atgtaaacga tagattaata
     3601 tatacgaatg acattgtaga agtagtgata gattctgcaa agcaagaagt gttaaataaa
     3661 aaaatactta atggtactaa agctgaacaa agagctttaa atattgatga gatatcaacg
     3721 gaaataacta gtatgataat aagtataatg aaagagaaac ttttgaaaga atacattcta
     3781 aaatgctatg ggcgtacata tcctgaagat aaaaataata tatacatata ttcactgaac
     3841 atatttgcta aaaaagagat ttttatgaga gaaacagtat ttactagggt gagaaattat
     3901 atagaagaaa atgattttat aaatgtagaa ggttttatta gatttagaat gagagaattt
     3961 atgaaatata tttctgctat aggtgatatt gcagttgagg agtatttaat aaagaaagac
     4021 caagatgaat ttataagagt tttaaaatac tttatagata ctcaagaaga aaagattgat
     4081 ttgcttaaag ttcatataat ggaagataat acatttgttt tatacgataa aaatggaaat
     4141 aagatagaca gtatagatga tgaagaaatt ataaatatgg taataagaga aaatttaaat
     4201 tatgaggact ttttaataag taccttatta actctatgtc ccaaaaaaat agaaatattg
     4261 gatttgttaa ataataattg ctcaaaggaa attatagata ctgtagaagc aatttttgaa
     4321 aataaagtta gtataattat ggaaaactag aatctaagca tataaaagct atccatataa
     4381 aattaaaaaa attcttttta aatcgacaca aaagacttat aattgtatat aaagctatag
     4441 tataactagt gttattaagt ataaagaata tctacttgat taatacaata tagctggcaa
     4501 atatacaatt gataaggagt aattttataa tggataattt aattaggata ctgatattag
     4561 ctgttattgg tggatttata ggttatgtta cgaatgtagt tgctataaga ctgatattta
     4621 gaccaataga gcctattaaa atacctattt taaatataga aatagtaggt cttataccaa
     4681 agagaagagc agaaatagca gcaaatgtag gagaaataat tcaagaagaa tttctttcta
     4741 tggacgaaat acttgcaaat atcattactg acgaagataa ggaagaagtt gtaagataca
     4801 taaaagcaag ggtaaaaatt ataatacatg agaaagtttc atttatcccg agtggtataa
     4861 aaaacatgat acaagattat ctaggagaga taattgagtc tgaagttaag caaagtatag
     4921 atgaattgag taaaaatata ataaataaag caaatgaacg tatagatata caaaaaatgg
     4981 tcgaagataa gattaatgaa ctagatttat atgaattgga agagataata ataagaatag
     5041 ctaagaaaga attaaaacat atagagtttt tggggcttgt cttagggttt ttaataggta
     5101 tagctcaagg gttaattact atgtttattt aaatatatga gaagtagcat ttatttaagt
     5161 actaattata tttacctatt tgagtgaatt acttattaat agcatttaga tattaattgt
     5221 atttatttat ttgattgtgt tacttattaa tagtatttaa gtatttactg tactacttat
     5281 taactatatt aagtattgat tgtatttaag tatacaaaac ctaaaaagag tacaaaaatt
     5341 agaagttagt tttaataaaa attagtttta gtatttatct agtcatatct atcatgcatg
     5401 tggatacgtt ttaaaaattt taaatttatg aaaatattat aatatcacta taaatcaaga
     5461 gattaattta atataaaaat ataagaatat tggtttacag ctgattgaga tgaaaaataa
     5521 tgggtaatta atatattaca ttaatgttga ttgatgtata actatctgtt ataatgaaaa
     5581 tatattaaaa atcatagtgt tgaagaggaa gagtagagta gaaaccattc tcagagaatt
     5641 tgggtctatg gctgagagcc catgtaatag gtctatttga aaactacctt ggagctgagc
     5701 ttattagcag tatttgtttt gtactatacg tgaaagtgct cgggtgacga ccttatagtc
     5761 atcaagaggg ttgtatatac ttgtatacgc caacttgggt ggaaccgcga attaatatcg
     5821 tcccaaacat atttggggcg attttttatt acaaaaaatc taaaaattat ttcaataagg
     5881 aggaaaaaac aatgattaaa gttgctttaa aagatggctc aataaaagaa tttgaaaatg
     5941 ctatttctgt tatggatgta gctaaatcca ttagtgaagg attagctaga aatgtggtag
     6001 cagcgtctgt gaacggagag gttgtaggtc tggaccacat tatagatact gattgtgact
     6061 tgaatttatt taagtttgaa gataaagaag gtaaggaagt ttttagacat acatcagcac
     6121 atatattagc tcaagctata aaaagacttt acccagaagc aaagcttgct ataggaccaa
     6181 gtatagaaaa tggattctac tatgatatag atttagacca tagattagtt ccagaggacc
     6241 tagagaaaat agaagctgaa atgaaaaaaa tagctaaaga agatttaaaa atagaaagat
     6301 ttgaacttcc tagaaatgaa gctttagagc ttatgaaaga acaaggagaa gactataagg
     6361 tagaacttat atctgattta cctgaaagtg aaataatatc tttctacaag caaggtgatt
     6421 ttactgattt atgtagagga ccacatttac catctactaa aaaggtaaaa gctgttaaat
     6481 tacaaagtgt agcaggtgca tattggcgtg gtgacgaaaa taataagatg cttcaaagaa
     6541 tatatggaac ttcttttgag aaaaacaaag acttagaaga gtacttacat ttactagaag
     6601 aagctaaaaa gagagaccac agaaaattag gtaaagaatt aggattattt atgatacctg
     6661 aagaaggtcc aggattccct atgtttttac caaaaggtat ggaacttaaa aatgaattat
     6721 taaaattctg gagagaaata cacagaaaag ctggatatat tgagatagaa tctccaatca
     6781 tattaaatag aaaattatgg gagacttcag gacactggta tcattacaaa gaaaatatgt
     6841 atacagttaa aatagatgat gaggattatg ctataaaacc tatgaactgt cctggtggat
     6901 taatttatta taactctcaa ctacattcat atagagattt cccaatgaga gttgcagagc
     6961 ttggtagagt tcatagacat gagttatctg gtgcattaca aggattaatg agagttagag
     7021 catttactca agacgattca catatattca tgttaccaga gcaaattaag gacgaaataa
     7081 aaggagtagc taacttaata gatggtatat acaaaacttt tggatttgaa tataatttag
     7141 aattatctac aagaccagag aactctatgg gaagcgacga agagtgggaa gcagcagaaa
     7201 atggattaag agaagcttta gaagagttag gtctaccata tactattaat gagggtgatg
     7261 gagcattcta tggtcctaag atagacttcc atctaaaaga ttgtttagga agaacttggc
     7321 aatgtggtac tatccaatta gatatgcagc ttccaagaca atttgataat acttatattg
     7381 gtcaagatgg tgaaaagcat agaccagtta tgattcatag ggttgctttt ggtagtatag
     7441 aaagatttat aggtatatta atagagcatt atgctggtaa attcccagtt tggttatctc
     7501 caactcaagt taagatactt cctatatctg ataaatttat ggattatgca aatgaagtta
     7561 agaaagagtt atttgataag ggtataagag ttgaattaga tgatagagct gaaaaaattg
     7621 gatttaagat aagagaagct cagcttgaaa aagtgccata catgctaata gtaggtgaaa
     7681 aagaagtagc tgataataat gtttctgtta gatcaagaga taaaggtgaa ataggtagta
     7741 ttaaattaga tgaatttata gctagtattt caaaagaaat tgaatcaaga gaaagtatta
     7801 ttcaagacta atatatatta tattagtagc taagatattg ttatataaga taagtttaat
     7861 caatatgttg atatgttgat gcatagtgat taaatttatg aaaagatgag tataattaga
     7921 ggtacagtta atcatatttt tatgattaat gtacctctag ttttttgtat ggtagattta
     7981 ttaataaata tatcatagaa gtgttttgaa catggaaata tttatgtgca ttctttaaat
     8041 aaacgtttat tttttgagtg ataattaagt gcttgttggt aaggttatgg ctgtaaaaat
     8101 cataacttta ttttcatatt tgttccattt tcataaaaat tattatccct ttaagaaaat
     8161 ttcttaatcc tcttgaaata tttccttttt agtctaaagt taaatttctt tcttcaaaat
     8221 gaatatttaa atgaactaaa atttaagtac attttctaat cttatgagtc tatttttcat
     8281 agataattgc cctataatag aagaatctat gttggtgcta tgtggtgaca ataacagcat
     8341 tgtcagtgat taattaatgc tttataaatg attaattagt gttttatgtt atttttggac
     8401 ttaccctcta tacatagatt aatttattta actttagata gagagagaat gtcaagtaca
     8461 tacacagaca ttagagttta agaaagtgtt tatggagcaa gaacttttaa aagaggtagt
     8521 gacttagttt aatttcaaga aatgataaat acaaaagagg aaaaagagag gtgttgaaat
     8581 gatagaaaaa gtagaagaaa aatctaagat tattaaaaca tcaaaagaat ataagcgaac
     8641 tataattgaa gaaaaagata aagaatggac caaaaaatta aatgatatac ttagtagaag
     8701 tagtttttct aatgatgaat tagataaaat caaggcgtta attccaaaag agattttgac
     8761 taatgaaaat gttggagaag ttgtgactga agatggatat gctaagcccg agtatgatga
     8821 ggtatttaaa tcattgttca ctttaaataa tgaatatgat ttacttgtaa attttataaa
     8881 tgatattcta aaagatgctc catatgctaa caggaatatc aaaccgttca ctcaaataaa
     8941 gagaataatt agagttgaaa ctgatccaac aattaattac attggagaga aaagacctaa
     9001 acttgatatt ttggctgaag atgaagaaaa taatcatata aatattgaga tgcaaagagc
     9061 ttttgagaac gattatttgg aaagagctga atattatctt agtcgtgtac atggtagaaa
     9121 gttagaagaa ggtaaagagt ataaagaaat tggaaaaact attggaatac atatactaaa
     9181 tcatgtaaaa tataatcaca tagaagatta tgtaaattgc ctgagattaa caatggacgg
     9241 gcatccagat atttattcta gtaaaactgc attatatttt atagagcttc caaaaattca
     9301 taaatctgac tatatagtaa atagaattat gctatgggga aaacttatta gtaatccttc
     9361 taacttagat gtaagagtta tagctaagaa tgattctatt attaaaaaag cacttgatag
     9421 attaaaagaa ttaggtagca atgaagaata tttattaaat ctgaaaagag gtgcttatat
     9481 catgaataaa agtagaaatt ttaaagaaga gattgaaaga gagacagcaa ttagagttgc
     9541 aaaagaaaaa gattataaaa taattataat gttgaaaaaa aatggtttta aattagatga
     9601 catattaaat aaatttaatg attttgactt aagtgaagat gagataaaag aagtatatga
     9661 aaataattga tgataaataa aaagtgaact tatataagtt tgctgaatcg gagtctggaa
     9721 atatttatgt gtatttttta atgaatgaaa atttatttta aaaacaataa tttagaagta
     9781 cagttaatta tatttttatg atactgtact tctagttttt tctattgtag atttattatt
     9841 tactaataaa tctacaatag aaatgctttt gttgtaagaa tcattttatc taatgattgt
     9901 tttttataat agttaaattt ccatttgtag tgtttaaata taaatctata acagcatttc
     9961 tataaatgtt ataaatcact ataatgattc aactcaaagt tactgcttaa agaagcagag
    10021 attttatcaa ggtatatcat ggaaaaaaat attttattgt aatatttata agattttatt
    10081 atggaaataa tgtaaaaact ttataaataa tatattttat acctagttat agataaattt
    10141 atatagttat tattaaaaaa agcaataaaa agtttaattc aatttagcaa atttagtgat
    10201 ataattaaaa aagaaaagaa atatggactt atttggaata attttgacaa tctatttact
    10261 acacgtgtag agtcgtatat aattaaatta tacataaaat ataaaaaaat aatttagtaa
    10321 tacgttagga gaaagtatta tgataaagtc aagcttattt tggaatattt tcattgcgat
    10381 atcctttatg atagaatggt ttctttgtaa gaaaatgcta gattatacaa gtgagaaaag
    10441 gatttctaac aaaaaaataa acttttgtgt ggtaggtatt attgtttttg ctgacataat
    10501 atattttttt gatgtacctc caaatataag agtaattata tctatgataa ttactattgc
    10561 attttataaa atctcatatg atgtggggtt tataaagtct gtattaatat ccttaattta
    10621 ttggatgtta ctaatcgcca cagatgcttt gagtatatct ttaacagttt ggcttaattc
    10681 tataaatgac atgagtagta tggggacggg agatatatac agaattgagt ctataatatt
    10741 gggaaagata cttttgattg tgtctttgct tttatataga gccttaaaga taaaacttaa
    10801 tatagaaata aataaaagga cattatttta tatagttatt cctatagtcg ctaatatagc
    10861 atcttttttt gtaatttttg aatacatatt taatccaggg tctggtagct taatacataa
    10921 tttccaattc gttatgattt ctgttgtatt gcttatatca agtatcactt tagttttaat
    10981 tgctaaaaaa ttacagcaat ataatacttt agttgtagaa aataatatga ttaaaaatac
    11041 tttgaagtat gaaaatgagt attatgaaga tatagaaaag aaatatttaa aaactagatt
    11101 actaagtcat gatatgaaaa atcacatctt gtgtataaat gctatgatta aaaaaggtat
    11161 tgatgttact tcttatttaa ataatttgca ggtagaaatt cagagtaatg acttgttatt
    11221 taatactggt aattttatat tagatgctat attaagtgaa aagaaagagg tttgtgataa
    11281 gaatgatata gaactaaaaa taggaataaa ttttagttgt tgtgaagctg ttgaattagt
    11341 ggatatatgt catatatttt caaatatttt agacaatgca attgaggcat gtaataaaat
    11401 tgatagtgga aatagagtta tttgtgttaa aggtgatgtt atgcaaaatt tttatttaat
    11461 aagagttgaa aatactaaga tgaataagat tattactaaa aatggagata ttttgacaga
    11521 caaaaaaggt tctcttcatg gacttggaat aaaaagtgta aaaaactctg taaataagta
    11581 tggtggtaat gttgtaattg aatatgatga taaaaaattt gtagttaaaa ttgctattcc
    11641 acttagaaat gtgaagaaag cagttaatca tgtgatttaa atgtatataa atttgatgtg
    11701 tagaaattta atatataaga attaatgtat aaaagtgatg catagaagtt taatatataa
    11761 gaattaatgt ataaaagtga t
//
LOCUS       DAGQVA010000108        11182 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.108, whole genome shotgun sequence.
ACCESSION   DAGQVA010000108 DAGQVA010000000
VERSION     DAGQVA010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11182
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.108"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            268..714
                     /locus_tag="MIV85_003448"
     CDS             268..714
                     /locus_tag="MIV85_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962755.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVP"
     gene            1095..2012
                     /gene="pstC"
                     /locus_tag="MIV85_003449"
     CDS             1095..2012
                     /gene="pstC"
                     /locus_tag="MIV85_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBY2962756.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQGIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            2014..2838
                     /gene="pstA"
                     /locus_tag="MIV85_003450"
     CDS             2014..2838
                     /gene="pstA"
                     /locus_tag="MIV85_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBY2962757.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            2857..3621
                     /gene="pstB"
                     /locus_tag="MIV85_003451"
     CDS             2857..3621
                     /gene="pstB"
                     /locus_tag="MIV85_003451"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBY2962758.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            3649..4302
                     /gene="phoU"
                     /locus_tag="MIV85_003452"
     CDS             3649..4302
                     /gene="phoU"
                     /locus_tag="MIV85_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBY2962759.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            4460..5329
                     /locus_tag="MIV85_003453"
     CDS             4460..5329
                     /locus_tag="MIV85_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBY2962760.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            5416..6852
                     /locus_tag="MIV85_003454"
     CDS             5416..6852
                     /locus_tag="MIV85_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBY2962761.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            6900..7727
                     /locus_tag="MIV85_003455"
     CDS             6900..7727
                     /locus_tag="MIV85_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBY2962762.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    8023..8285
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8361..11027
                     /locus_tag="MIV85_003456"
     CDS             8361..11027
                     /locus_tag="MIV85_003456"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBY2962763.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
BASE COUNT         4415 a         1195 c         2088 g         3484 t
ORIGIN      
        1 tattaaataa taaaatagtt aaataataag attaagaatt tcttaataaa tccagaagat
       61 gctttcgatt atataatatt ttatattttt atattattaa ttatatgtgt tgcaatcgct
      121 gcacctactt tttctggtga gtatcagaca caatcagata gcatccttcg ttgtacgaaa
      181 catggacata ttcgtctagc gtttactaaa atattagctc tattttctat atttataata
      241 atgtttgtta tatgtatttc tatccatttg gcaatttctg atttagcttt tggtactgaa
      301 tgtttgaaaa cctcatttca aatgttgttt tctgtcatta gtctagtaaa tataaattta
      361 ctacaagcac agattcttat agctattggt ggtctaattt caatacttgc aatggttagt
      421 ttaacattat ttttatctgc aaaatgtaag gattctctta cttctatgct gattgctttt
      481 tctatttgct taattcctat gggaataggt gttagttgga ttggatacct attaccacca
      541 gggggaattg gttttaagat tagtttatta tatcaaatga catcatttaa tttcttacac
      601 ttaggaggta tgagtttttg gacaccacac attatactgt ttttctcagt gatagaaata
      661 cctattttta tatttttggc tattcgtacc tattgcaaac atcaagtacc gtaacaattt
      721 gatggaaata atagtgatat aaactagagg atacaataat tatatatgta gtataaaagt
      781 taaatttagt taacaaatct taatagcaga tataggtaat aaattataca taaactgtat
      841 tattatctat atctgctatt ttaatataga gaaacaacag tatattgtaa agtaaatgtc
      901 aaatatagtt ttaaaagtaa aattaatgtt aaaaagtaaa tataatttta cacttgctta
      961 acttaatcct aatatagatt taacttaaaa aaagtagaat aaaagtatag gaaatttgat
     1021 gaagacgaat tataaaaaat taaattttga atacagaacg aaaatcgata agtatatttt
     1081 aatgggaggg tattatgata gtaaaatcta gattagtagg tttagaaaaa aatgacaata
     1141 atggcaataa gacaaaatac gtaattgaaa aagtagcaaa aaatattttt ctacttagtg
     1201 ctttagtagc agttgcaagt ttacttttga taataggatt cgtattttat aaaggattaa
     1261 gaccatttat atttgaagga tattcattta tagacttttt aactggtgca gattgggttc
     1321 cttctgccaa taaatttgga atatcatcta tgatagtagc atcaatattt gcaacacttg
     1381 gagcacttgt tataggagta cctgttggta tattaacctc tgtatttata gcagaagtag
     1441 cacctaaaag attagcaaaa ataatgtcac cagcagttga acttttagca ggtatacctt
     1501 cagtattata tggtgtattt ggtcttgcag tgatagttcc aactatacaa ggtatattta
     1561 atcttccaaa aggtcaaagt ttgttagcaa tagtaatagt attagcagta atgatgttac
     1621 caacaataat atctgtatca gaaacagcaa taagagcagt accaaaagca tacaaagaag
     1681 gttcattagc acttggtgca tcaaaaatag aaacaatatt caaagttgta ttacctgctg
     1741 caaaatctgg agtattagcc gcagtagtgt taggagtagg aagagcttta ggtgaaacaa
     1801 tggcagtaat acttgttgca ggcaactcac cagttatgcc aactgcaata acagatagtg
     1861 taagaccact tacaactaat atagcacttg aaatgggata cgcatttggt acacatcaag
     1921 aaatgctatt tgcaactgga gtagtattgt ttacatttat attaatttta aacttagttt
     1981 taaataaact ttcaaataag gcggtaaatt aagatgagaa agttcaaaga gaatctattg
     2041 aagtcattag tatatctatc agcactattt acaatagtat cattagtagt tatagtggga
     2101 tttatattta taaagggaat tggcaacatg aattttaatt tcttatttag caattattca
     2161 gcatcaggtg atggtggtat acttccaatg ataattacaa cattatatac agtagtagtt
     2221 tctatagttg tagcaactcc tataggaata ttggctgcta tatatttaca agaatatgct
     2281 aaaaaaggaa aagcagttac agctataaga tttgcaactg aaagtttatc agggatacca
     2341 tctatagtat atggattatt tggaggaatt ttctttgtag ttacattaaa aatgggatat
     2401 tccatagttg caggttcact tacagttgca ataataatat taccagtaat aattcgtaca
     2461 acagaagaag ctttaaaaac agttcctcaa gcttatagag aatcatcatt ggcattagga
     2521 gctacaaaat ttcaaacttt atataaggta gtacttccaa gtgcaatacc aggaatttta
     2581 tctggagtaa tcttatcagt tggtcgtata attggagaat cagctgcaat attacttaca
     2641 gcaggtactg tagccaagat gccaggtgga atatttgata gtgcaagaac attaactgta
     2701 cactcatact tactgactaa agagagtgga gatatagcaa cagcagccag tataggaatt
     2761 gttttaatag taattgtatt agcactaaac atgctagcaa gatttgttgc taagaaatta
     2821 aataaagcta attattaaat ttaagaggtg tgaataatgg aattaatcga taagataaaa
     2881 atgagtgtaa aagatttgga tttattttat ggtgataagc aagcattaaa gaaaataaat
     2941 atggatataa aagagaataa ggttactgct ttaataggtc catctggatg cggaaaatca
     3001 acttttataa gaacgttaaa tagaatgaat gacttaatcg aagatgtaac aattaaagga
     3061 aacatttctg ttgatggaga ggacatatat acctcagatg atgttataaa tcttcgtact
     3121 aaagtaggaa tggtatttca aaagccaaat ccatttccta tgagtatata tgataatgtg
     3181 gcatatggtc ctcgtacaca tggactaaga gataagaagc aattagataa aattgtagaa
     3241 gaaagcttaa aaggtgcagc tatttgggat gaggttaaag acaggcttaa atcatctgca
     3301 ctaggacttt ctggtggtca acaacagcgt atatgtatag caagagcaat tgctatgaga
     3361 ccagaagtta ttcttatgga tgaacctaca tctgctttag acccaatttc aacattaaaa
     3421 gtagaggaac ttatagagga tttaaaaaaa gactacacaa tagtcatagt tacacataat
     3481 atgcaacaag ctgctcgtat atcagatgaa acagcttttt tcttaaatgg agaggttata
     3541 gaatttagcg atacaaaaac tatgtttacc actcctgtag ataaaagaac agaagactat
     3601 ataacaggta gatttggtta aaatatataa ctataaagga gttagacaat ggtcaataat
     3661 agtttagata taagtattga tactttaaaa gaacaaacag tgcttatgat ggaaaaatgt
     3721 gaagaagcaa tagaaaagtc tgtgacttgt atgatagaga aggatttaga gggtgcaaga
     3781 aaagtagtag aagatgatga agaaataaat aaattaagag aagaaataag agataagagt
     3841 atagagctaa tagtattaaa gcaaccaatg gcaagggact taagatttat ttattcatta
     3901 ggtaatatat ctatagagct ggaaagaata ggagattatg cagcaaatat agctagagaa
     3961 atgttgaaga taggtggaga ggcttatata aaagagctaa tagatattcc taagatggca
     4021 aaagaatgta agtctatgat gtctcagact agagaagctt taatcttatt tgatgcaagt
     4081 atagcttatg atgttggaac taaagatgat attgtagatg gattgtatga acaagtacaa
     4141 attgattgtt taaaaataat gcatgaaaac tcaaatacca tagaccaagg ggtaaaactt
     4201 ctacttatag gaagatacct tgaaagaatt ggagaccata taacaaatgt atgtgagaag
     4261 ataatttttg caattgaggg taaaatggtt gagataggat aaaaaactgc tttaaagcag
     4321 tttttttatt gtctaaatta agaaagaatt gataaaaaaa tatgattaat gggtaaattt
     4381 aaaaaattgt gatatactag gaacatatta aatatgagga tgcgtatttt atataaggtg
     4441 ctttttagga ggtggaactt tgaaacttca aaagatgggt atgaggacta taaaaacagg
     4501 aattagtgtc actttatgta tgattcttgg tgactattta gtagagaata tgttttattc
     4561 tctggtagca tgtataattt ctgttcaaga tacagtaaaa ggttctttaa agacgggaat
     4621 caatagagtg gaaggtacta ttttaggtgg tataatagga ttcatatttg caatcattaa
     4681 agctggagac ccatttttat gtggtctagg agtaatgtgc tcaatatatt tatgcaatct
     4741 gtttaaaata aagtcagtag tagttgcctg tgtaaccttt ctggctatac atctaggtgt
     4801 aggaaatagt gaccctgtgt attattcttt acatagggtg ttagatacat ctgtgggtgt
     4861 tttgtttgga gtacttgtta attattatgt tgctagacca aattatctaa atagtgttat
     4921 agatgagttt aaaaagatag aagaactttc aatgttgctt attgaagata aaattcttag
     4981 aaaagaaaat ttaaatgtag agaaatttga agaagaagta gaaaaattag aagaaatata
     5041 ttcaaaactt attgatgagt tggattatag tttgagtgaa actaatatag aaaaaattga
     5101 gaatgcctta aggatatgta gagaaataca ttttcatatg cagtctatag agttacttga
     5161 aaataaactt tatttgaaag agcatacata taaatacctt aagaaaacat ataatgtgga
     5221 taagctagac tggaatatag atgaagaaaa aagccctgta ttcaactatc atctaatgaa
     5281 aataatgatt gaaatagagt tgttgagaaa gctaaataaa tcatattaat aatagtagtt
     5341 aaataataaa taaaaaatag tatctttgta aatattaaac atatataagt ttaatttatg
     5401 gaggtactat tttttatgaa tactagaaat gacaattcta aaatactaga aatatataaa
     5461 atgaagcttt ttggcgaact tgtaaaagca gtgtggaatg atgatataga ggatattgaa
     5521 aacttaccta ataaaatttt aaatgaagat ttaaaggata atttaaataa ttattttagt
     5581 ggaaaatttg ataaagatac tatggtaaat ttaattaggg taactatggg attggatgtt
     5641 acagaagata cagataaaaa tttaaaagag tcactgcatg aagctgtaaa tttagatgaa
     5701 gtcaaaagac caataatatc tgtaatatca gatgcttgca aatattgtga tgaaaataat
     5761 aaggaagatg agtcatgtaa gataagaagt aagcatatta attgtaatga ggaagatgta
     5821 tgtagtgctt gtggtgattg tgtatcaaga tgtaagttgg gtgcaatttc agataaaata
     5881 gaatttatac caatgataaa attgttaaaa gatataaaga gccctgtata tgcaatagtt
     5941 gcaccagctt ttgtaggaca gtttgggaaa gatgtaagcc ctggtaaatt aagaactgca
     6001 ttaaaaaaga taggatttga agatatgata gaagttgctt tggcagcaga tatgcttact
     6061 gcaaaagaag catatgatta ttatgagcat atgaaaaagg acgaagaagg atgctttata
     6121 actagttgtt gctgtcctat ttgggttagt ttgatacaaa atagttttcc tcagatattg
     6181 gaaaatgtat caccatccgt ttctcctatg attgcttgtg ggagagctgt aaaaatttta
     6241 aatccagatg ctaaagttgt attcataggt ccttgtatgg caaaaaagaa agaagcaatg
     6301 ttagaagata taaaagatgc agttgatttt gtgcttacat ttaaagagtt gcaagaaata
     6361 tttgatgcat tagagttaaa tccagcaata atggatgaga gtaatagagt agaggcgtcc
     6421 ctttcaggta gagtttatgc tagaacagga ggtgtaagta aagcagttaa gttatcagtt
     6481 agaagaattg acaaaaatat aaaatttgaa gaaaaggcat ttgaaggaac aaaagagtgc
     6541 atggacggtc taaagaaagt tctaaataaa gaaatagaag ctacatttat agaaggaatg
     6601 gggtgtgtag gaggctgtgt aggaggtccg aagcgtattt taagtgtgga agaaggtact
     6661 aagaatgttg atgaatatag tgaaagtacg aatatggaaa ctccatttga taatttaaat
     6721 gtattacaat ttttaacttc tttgggaatc aaaagagtag aatctttagg agaaaaagaa
     6781 gaagaaaagg ttaaaaaaat atttagtaga gatataaaaa gtaataagaa agagaataaa
     6841 tataaaaaat aactttttaa gtcttaaact tatgctttta taaaagggag atatggggga
     6901 tgaaaattaa agataataag gctgtttttc atgtatttat aaggatattt cttatagctg
     6961 ttttaatttt aactggaaca ttattggagg aaaaaattaa taatgttcca gttgaaaata
     7021 taagttcaaa aggtgaaaat acactggaac tgctttctca aagtaatact ttaggagaaa
     7081 tcatatacaa agcatctcaa gaagaaacaa aaggtccagg ggctacttct gaaaaagtag
     7141 catacataac aatagatgat ggtccatcaa aatatacaaa tgcactactt gatattttaa
     7201 aagaaaatga tgtcaaagcg acatttttca tgcttaatca gaatatgaaa aaccacaagg
     7261 aagaagtaag gagagtcttg gaagaagaaa actcaatagg ttttcatagt gtaagtcatg
     7321 atatacataa gttatataaa agcccagaag taacagttgg ggaatttaat acatgcaata
     7381 atactctaca agaaataact ggtcagagtt caaaattaat aagattacca tacggaagta
     7441 aaccatatat gccagaaggt tcatataata aacttatggc aaatgattat ttaatttggg
     7501 actggaattt ggatacacag gattggaagt cttctacaag tcagatagta agtaatatat
     7561 tatattatgg aagaaaaaga gatgaattag tagtattaat tcatgagaaa gagcaaagtt
     7621 taaatgcttt aaataatatt ataagaatct taaaagagag aggatataca atattgccaa
     7681 ttacagaaaa tataacacct aaaaatttct ggcaagaaaa cttataataa atttaaatat
     7741 agtaaaagat aaagtaaatt atttataaaa taaaacatat aatataaaaa atacgaataa
     7801 gaggtatact gtaaggataa tataaaatta atgagaaagc attaaaatta aaataaaata
     7861 atcttgcaat tattgacatt ataagacaga ataactgtaa aaacatattt taaaatataa
     7921 caactatata aaagagaata gacataatta agaaaattca gaaaaaataa aataaaaata
     7981 attgacaaag agaataatat ttgtatataa taatatgtaa tattaaagac tgagaagaag
     8041 aggagtaagt aaatactact aaaagagagg aaaattcact ggctgtaaga ttttctaagt
     8101 ataagattta ctgaatgtag ctttggagtt tctaaactga actataagta agtttagacg
     8161 gttagaaccg ttaaattctt tgagagtcaa agttgataaa ataacattaa ccaataattt
     8221 aattatatgt taatgtattt taagctttgg aattaaggtg gtaacgcgag cttttcgtcc
     8281 tttttaaaga ggatgaagag ctctttttta tttctaaaga tatttaaaaa atttatttat
     8341 aaaatacagg aggcaggaca atggaaaata cgaatttatc aaaaacttat aacccaaaag
     8401 attttgaggc taggctatat aaaaaatgga tggatgaagg gtattttaaa tctaaaccaa
     8461 atccagataa aaaaccattt acaataatga tgccaccacc aaatataaca gggcaattgc
     8521 atatgggaca cgctcttgac catacacttc aagatatatt aatcagatgg aaacgtatgg
     8581 atggatatga agctttttgg cttccaggaa ctgaccatgc ttctatagca acagaagtta
     8641 aagttgttga aagaataaaa aaacaagaag gcaagacaaa gtatgaaata ggtagagaag
     8701 aatttttaaa gagagcctgg gaatggaaag atgaatttgg aggaaaaata tctaatcagc
     8761 ttaaacaact aggtgattct tgtgattggg ataaagaaag atttactatg gatgaagggt
     8821 gtaatgaagc agttatagaa ttttttgtaa gcctatatga aaaaggtcac atatacagag
     8881 gaaatagaat aataaactgg tgcccagatt gcaaaactac tttatcagat gcagaagttg
     8941 aacatgaaga acacgacgga aacttttatc atataaagta cccactaaaa gatagtgaag
     9001 actttttaga aatagctaca actagacctg agacaatgat aggagatact ggtatagcag
     9061 taaatccaga agatgataga tataaacatt taataggaaa aacagcaata cttccattag
     9121 taggaagaga acttccaata gttgcagata gttatgttga tttagagttt ggaactggtg
     9181 cagttaagat gactccagca catgacccta atgattttga agtaggatta agacataatc
     9241 ttgagcagtt aaatactatg aatgaagatg gaactatgaa tgaagtttgt ggaaaatatg
     9301 aaggtatgga tagatttgag tgtagaaaag ctatcgtagc agacttaaaa gaacaaggtt
     9361 acctaattaa gataaaagag cataatcata atgtaggaac ttgttataga tgccatacag
     9421 tagttgagcc tagattatca gagcaatggt ttgttaagat ggaagaactt gcaaaaccag
     9481 ctatagatat tcttaaaaaa ggagaattag aatttgttcc agataaattt gataaaactt
     9541 atttacaatg gctagaaaat ataagagatt ggtgtatatc aagacaatta tggtggggtc
     9601 atcaaatacc agcttattat tgtcaagagt gtggagaaat agtagttgct agaaaaatgc
     9661 cagataagtg tcctaaatgt ggaagcactc attttaaaca agatgaagat gccttagata
     9721 cttggttcag ttctgcatta tggcctttct ctactctagg atggccaaat aagactgaag
     9781 ctttagatta ttattatcca acaagtgtac ttgttacagg atacgatata atattcttct
     9841 gggtagttag aatggcattt gcaggtatgt tctgtatgaa tgaaaagcca tttgaccatg
     9901 ttttggttca tggattagta agagattctc aaggtagaaa aatgagtaaa tctttaggaa
     9961 atggtatcga cccattggag ataatcgagc aatatggagc tgatgcccta agatttacat
    10021 taacaactgg aaattcccca ggaaatgata tgagattcta tatggaaaga gtagaatttg
    10081 ctagaaactt tgcaaataag ttgtggaatg catcaagatt tgtatttatg aatattgatg
    10141 aagatataat taaaaacatg actagagaaa gtgttaaaga ggacttaact ctagctgata
    10201 aatggataat atcaagagca aataatattg taaaagaagc aactaataac atggataagt
    10261 ttgatttagg aatagcactt caaaagatat acgattttac ttggtcagaa tactgtgact
    10321 ggtatattga aatggttaaa cctagattat atggggaaga tgcaaatgct aaatctgcag
    10381 cattatatac attaacttat gttcttgaaa agatattaaa attattacat ccatatatgc
    10441 catttataac agaggaaata tatactcatc ttcctactgt tgaaggatgt ataatagtat
    10501 ctgaatggcc aaaatataat gaagaagata acatggctga agaagaagat atgatgaact
    10561 tattgatgga aggtataaga agtataagaa atgtgagagc agaaatgaat gtaccacctt
    10621 ctaagaaagc taaattgata ataatcccaa gtgaagaaaa aatagaagct attgagcttg
    10681 gtaaagacta ttttataact ttagcatctg cttcaaatgt agagatagca aaagataaat
    10741 ctaatgttcc agaagatgca gttggagtag ttattgatgg tgttgaaata tttatacctc
    10801 ttaatgaatt agttgatttt gaaaaagaaa ttgagagatt atctaaagaa aagaaaaagt
    10861 tagaaggcga aataaagaga gttaatggaa agcttgcaaa tcaaggtttc ttagcaaaag
    10921 ctcctgaaag tttaattgaa gaagaaaaag caaaaaaaga aaaatttgaa gagatgatta
    10981 aatctgttga ggaaagatta acaaatttag aatctaaaat aaaataaata taagaattag
    11041 taaaaacata caaaaagtat atattctata ctttttgtat gtttttcttt atatatatac
    11101 aaatatgatg ttataattct ttacagatgt gttatatttt tattttatgt tgtgaatata
    11161 tgaattttat gtcttaaaat tt
//
LOCUS       DAGQVA010000109        11128 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.109, whole genome shotgun sequence.
ACCESSION   DAGQVA010000109 DAGQVA010000000
VERSION     DAGQVA010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11128
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.109"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            418..2430
                     /locus_tag="MIV85_003457"
     CDS             418..2430
                     /locus_tag="MIV85_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2962764.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            2799..4019
                     /locus_tag="MIV85_003458"
     CDS             2799..4019
                     /locus_tag="MIV85_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBY2962765.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAVVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            4056..5405
                     /locus_tag="MIV85_003459"
     CDS             4056..5405
                     /locus_tag="MIV85_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBY2962766.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKKGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFVGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPIVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(5537..5830)
                     /locus_tag="MIV85_003460"
     CDS             complement(5537..5830)
                     /locus_tag="MIV85_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962767.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
     gene            complement(6316..6519)
                     /locus_tag="MIV85_003461"
     CDS             complement(6316..6519)
                     /locus_tag="MIV85_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962768.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
     gene            complement(6570..6821)
                     /locus_tag="MIV85_003462"
     CDS             complement(6570..6821)
                     /locus_tag="MIV85_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HBY2962769.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            complement(6837..7907)
                     /locus_tag="MIV85_003463"
     CDS             complement(6837..7907)
                     /locus_tag="MIV85_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HBY2962770.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            complement(7936..9357)
                     /gene="ccpM"
                     /locus_tag="MIV85_003464"
     CDS             complement(7936..9357)
                     /gene="ccpM"
                     /locus_tag="MIV85_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HBY2962771.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVSKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            complement(9379..>11128)
                     /locus_tag="MIV85_003465"
     CDS             complement(9379..>11128)
                     /locus_tag="MIV85_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962772.1"
                     /translation="FKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSISLLVSQNII
                     NNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIETMMLEKSL
                     TLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVVLSQFQLWL
                     IIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYKEIMVFRIG
                     SKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQGILKKILI
                     GDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSIEHIKIFEK
                     IGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTLLKILLGFY
                     DDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVYKSNLEEKV
                     KSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDADMYIFDEP
                     DSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKLLESGRHDE
                     LMDKKGVYFNLFCNCK"
BASE COUNT         4225 a         1511 c         1297 g         4095 t
ORIGIN      
        1 aatttatgtt atttttaata aaagatagaa ttacaactaa attaaacttg acaaatccat
       61 tctactcacg cagaataaac ttatacatat atattttcat atataattta ttttaatata
      121 attctatatt tataaaatta tattatcaat agaatttatt aaaataaatt tttttgggtg
      181 tatattataa tttaatcgaa tagaaatgaa aaatatacat acagtttaag ttttaagcaa
      241 caattagggg gatttggtga caagattttt aactataaga aagaaagtgt cttaatgcaa
      301 cttttagaaa gtcattatag acactttctt ttttatttga taaatttaaa ttatcaaaat
      361 tagattgctt tatacaacta ttttgttgga aactatttat tatataagga gaaataaatg
      421 aaaaaatcag tagctctggt aaatgatagt agaaaagatt taatagactt tttagaaaat
      481 aatttgaaat tagtttttgg agattctata aatattaata gatacttcat aaatgaaata
      541 aatgataatg atattataaa tgatgatgtg atattagtaa tgtcagtaga aagattagac
      601 aaaattataa ataatatact agataagaaa aaagtgattg tggtaagaag aacttttagg
      661 gaagataaaa tttataatct actatcttta ccacagggta caaatgttct aatcgtaaat
      721 gattctgatg aaactactct agaaactata agtttatttt ataaaattgg agtgactaat
      781 attagaccaa ttccatatat gaatgataat aactataaaa atataaaaat agctataact
      841 ccaggagttc cagaaaaagt acctagcttt atctcagata tatttgattt aggtcacaga
      901 tatatagata tctctacatt tatagaaata ataaatttat tacaaattga ttcaaaggaa
      961 atacaatcta atctagttaa atactcagaa gaaataataa gtttagatac tggtataaaa
     1021 gataaatata aggaattatt tttaaaaata gaagaattag atacaatctt gaatttatca
     1081 aaagatggta tattatttac ttcaaaagat ggtgaaataa atacatataa tagtaaagta
     1141 aaagatattt tagacataaa tgaggatata tatggaaaat acattgagga tatatttgta
     1201 gatagtttaa aagttttatt gagtgagaaa gagatactag ataaagttgt cgtattcaat
     1261 aagaaatata taaatgtaaa taaaaaaaac atatacaata gagatgaaaa aatgggcaca
     1321 tattatagtt tacaagaaat aacatacata aaaaaattag aacaaaatct cactaaaaaa
     1381 ttaagagaaa aaggacaaat agcaaaatat acatttaagg atataaaaac aaatagtcct
     1441 aaaatgtttg aatgtataga tttagctaag aaggtttcta aatctgattt aagcatactt
     1501 atcagaggtg aaagtggaac tggtaaagaa ctcatagctc agtctataca taacaactca
     1561 aatagaaaaa atcaaccctt tatagcagta aattgtgcag ccgttcctga aaatttatta
     1621 gaaagccagc tattcggata tgacaaggga acttttactg gaggtctaaa agatggaaaa
     1681 caaggattat ttgaacttgc taataatgga acaatattct tagatgaaat aggcgatatg
     1741 cctttagaat tacaaacaaa actacttaga gttcttcaag aaaagcagat aatgcctgtt
     1801 ggatctcaca atgtaattaa tatagatgtt agaatcatat ctgctacaaa taagaattta
     1861 gaacaaatga ttgataatag ccaatttaga gaggatttat attatcgatt aaatacaatt
     1921 ccaataaata tacctcctct aagagaaaga aaagaagaca tattaattat tatggaagat
     1981 ttaattaata agaaattagt aatcacacca gaagcaaaaa aacttataca aaactatatg
     2041 tggaaaggta atataagaga actccaaaat gttacatcct atttaaacat tatgtgtgaa
     2101 gatattgtat tagagaaaga tttacctcca aacttaaggt cttcagataa caaaaataca
     2161 tcattaaaac taaaatatag taagaatgat atattgaata tattagagat actaatttta
     2221 aataaggaat cagatgttgg tattggtaga ggattaattt taaaagcact actcgataag
     2281 aaccttcaaa ttacagaagg aaaaattaaa aaaatatttg aatatctaaa aaaagaagaa
     2341 cttataattt gtagttcagg aagatatgga agtaaaataa ctcaaaaagg agaagatttt
     2401 tacaataaat taaaatataa aggtctataa aattataatt tatcaaacaa agaaatctat
     2461 tcaggattaa agtactcctt caataggttt ttttattttt caagtaccct aaaattataa
     2521 tttattttgt acataaataa taggaattaa taggaatagg ataatttttt tatttcctat
     2581 tttttttata taaactagca tataaaatat attttcttca aaataatatt ttttactgaa
     2641 aattgaaact atgcaatcat tttttatact atacatatag ataaatgatt atatttattc
     2701 aatattctta taaaaaacaa aattctccat cgaaaattat ggcataataa ttgcttatta
     2761 tattaataaa acaataaaaa gcaattggag gaataaaaat gcaacaggct ttgaaattaa
     2821 aatatcaaac caaagaatta ggaaaagatt ttgtaataga aagttgtaat tctataaaac
     2881 catggcttat aaacataaga agagaattac ataaaattcc agaattagct cttgaagaaa
     2941 atcttactaa acagaaggta atttcttatt taaaagaaat cggaattgat tatatggaat
     3001 ttacaaaaca caatggaatt atggcatata ttttaaaaga aagtgcagat aaaacgattt
     3061 gtataagagc agatatggat gctcttccta ttgaagaaga aaacaacata ccttataaat
     3121 caatacattc tggaaaaatg catgcttgtg gccatgatgc acatacaacc atgctacttg
     3181 gagcatgtaa agttttacat tcaataaaag ataaacttaa tgtaaatgta aaattcttat
     3241 ttcaaccagc agaagaaggt tttggaggag caaaattttt agttgaggat gggtgtttag
     3301 aaaaccccaa ggccgattat atattcggac ttcatgttat gccacatata gaaacaggcc
     3361 ttatcgaaac aaaatatgat acattaaatg ctagtgtaga cactataaaa ataagtatca
     3421 aaggtaaaag agctcatggt gcatatcctg aaaacggtat tgatgcaata gttacagctt
     3481 cacaaattgt tacatcatta caaactataa taagtagaaa cttagaacca aataatgctg
     3541 ttgttttgac tataggtaaa atatatggtg gtgatgcaca caatgtaata tgtgaagatg
     3601 taaaattaga aggcacttta agaaccttaa atagcaaaac aagaaacttt atgattgata
     3661 aaatagctaa aattgttgga gatactgcat ctgcatttgg ttgtgttggg actttacatg
     3721 taagtgatga aaactatcct gctgttataa atgaaaaaga attagtagat acagttatat
     3781 caaatactaa agaattactt ggagaggaaa aatttatatt gagaccaaac ccgtctttag
     3841 gtggtgaaga cttttctttt tacacagaac attgtaaagg agcattcttc catttaggat
     3901 gtaaaaatga ggaaaagggc ttaatttcac ctcttcatac ctctagcttt aatatagatg
     3961 aagattgttt accaataggt gttatgatgc atgtaatgaa tactttgtat tttaattagt
     4021 acagtaatta ataaaagaat aggagataaa ttaatatgga aaaagctaag aaattaggtc
     4081 tatttagtat gatattatta gggattaata gcataatagg ttcaggtata ttcttactac
     4141 caggtaaagt ttataatcta gcaggtcaaa acagtatgtt tatatacatt tttgctacac
     4201 tcttagttct atcaatactt ttatgttttg cagaagttgg aagcatgttt gataagaaag
     4261 gaggagcata tctatactcc aaaaaagctt ttggagattt tataggattt gaagttggta
     4321 caatgtcttg ggttattaga attatatcat ggtctactct agcagtagga tttgcaacag
     4381 ctttaggttc attttggcca gaatctgcca ctgaatacaa aggttatata gctgcaatac
     4441 tcgtaacact actttcaata aatagcttat ttggaattaa aagcacaaag ataatgaata
     4501 atgtaataac tatagctaaa ttagtaccat taatagtttt tataatagtt ggaatatttt
     4561 ttataaaatt tgtaaatatt gttccttcag gaaatgtagt taactctagt atgggtccag
     4621 ccattatatt agtattttac gcatttaccg gctttgaatc atttattgtg gcaagtggag
     4681 aaatggaaaa tcctaaaaaa aatcttccag tcgcattaat aaccacaata tttatatgtg
     4741 caataattta tatattaatt caaattgtct gtatgggtat acttggagat agactatttg
     4801 aaaacagtat tccaattgca gatgcttcaa gtgtatttgt aggcaattat ggtaaagttt
     4861 tcatatctgt agcaacatta atatctatat ttggtataaa tataggttca tcaatagtaa
     4921 ctcctaaatg tggttcttct ctagcagaag aaggttctct tcctgcattt ataggaaaaa
     4981 caaataaata tggtgctcca tatgtagcaa taataatatc tttaatttgt tgtataccac
     5041 ttgtgctaac tggaagtttt gaacaacttg cagtaatgag cgtaattgca agatttgctc
     5101 agtacatacc aacttgttta tcagtaatag ttttaagaaa aagaacagat gttaaggcct
     5161 cttttaagat tccatttggc cctgttatac caatagtagc tattttaggt agcttatggt
     5221 tgttacaaca agcttgggca gaagatattt caaaacctat aactcaaaat agagttttaa
     5281 taggattagg ggcaatgttg ttaatagctc ctctatatat atttatgaaa aaaaataagg
     5341 aaatcgagca taaaaataaa tcagaagatt ctaaattata tatttcgaga gaaaaaattc
     5401 aataatattt tatactatta cttctcataa aatataataa atataaaaaa attgtagata
     5461 aaactatttt ataaaattta tctacaattt ttttatataa acatatatca aaatcaaaat
     5521 attattaatt tatactttaa agattcccat ctttatcata ttttattctt ataagaaaat
     5581 ataatcctat tactactaac tctatcacta aaaatactcc ataggtaaga attgaatcaa
     5641 tactatctaa cccatttcta aaaaaaatta atgctatacc tgctgctata atccctatag
     5701 cattttttct tactgcattt tgcccaactc cataaaaacc tggcattttt ccttttattt
     5761 cgacagcagt taaaattatc ccaaacacta taaataatac tccaataagc atcataatca
     5821 tactaatcat ctaattacct ccttcactta aggaaatttc aatttctaaa atctaaaata
     5881 aataatattt attttttata ataatattgt atatccaatt aactattttg gaaattagta
     5941 ccaataaata atgtttaaat attgaaataa tatattaatt ctaatcaata ttattaatat
     6001 atatatacat ttttacaaat atatttaaaa actttacttt taattcttac tatttaaata
     6061 agtataattt attataataa cttttaatta atttatactt ttaaattgta aaaatcaccc
     6121 ctaatcacta tatttaccac tataataatt gaagaggtga tttatataac agatactatt
     6181 tatgcagtta ttataaaatc acactcttaa ttataatcaa ctgcatattt ttataataaa
     6241 aggaaataaa gtaagaaaga taaatttaat caaatatgct aaatcaattt aatagtatac
     6301 ttattactga aatatttaca ttccatcagg agttctttgg ccatgtatca atttattata
     6361 atatgtatta tatgatcctc ctcttgcatt ataatcatta ttcttgcagt tacaagatga
     6421 agatgccatc atcttacaag tataaggaca cataatagta caaacacctc ttgtctcaac
     6481 acctatatta ttcatttcta ttctttttcc aaaactcatt catatcctcc ccttttctat
     6541 aagatcactt actttatacc tttattaacc tataccatat tgattatttt tagaacatta
     6601 tcaaaactcg taaattgcct attcaaaagt ttttcctctg gaatttttat attaaagttt
     6661 tctattacct cgcaaaatac taaaagtaat tctcttggct gtatatgtaa agacggtgaa
     6721 aaaaataatt ctttttttaa attgttattt ttattaaaat taattccagt cacatcaaaa
     6781 aatatattct ctagtagtaa ttccttttca gtgtaattca taattaacct ccaattctaa
     6841 atagatatta ctttagcata ctcttttaat tgattcacta tattgtccac taattctagt
     6901 aattgtttat tatcatgtat aaaaaatgtt ttttcataat cttctatatc ttcaacaaaa
     6961 aagttttcat ctaatgacat atatgaaaat ttttgcttca cctctgtctc atatgtatct
     7021 ataacttttt tctctatact aaaatagtct atatttatac catgtcttcc tttaataaaa
     7081 tatttaagtt cttcacaata ttctctatca tatatacttg atggaataca taatatacca
     7141 caatcattta ttactgcatt agaaatttca aaagctctaa ttccaaaatt accaaccatt
     7201 tttctagaga aagggaataa ttctcctgga acttctataa ttattaaatc tggctttgcc
     7261 tctacctctt tatcttttat aaaatggtta aaattaataa tctttgtctt actacttatc
     7321 gaatcatcaa acataaactc tggtatagga atcattttaa ataaatagct ctctttttta
     7381 gggccaaatt gtaatattga aaaccccctt tttcttagtt cttctcctat ccttatattt
     7441 acatcaaaag tatctaaccc tccataaaga ccacaaataa atattattgg tgtgtttatc
     7501 tgtgatatac cctctatatc tcttatttca tatttttcta aattccattc attaatcttt
     7561 ttgaattcat aatgagatat atacctagat attttattaa gatcatcacg tgtatataat
     7621 atctttttac cttcttttag agctactttt aatttaggaa ttataaattt ttctaagtct
     7681 agattttctt ttgaatcaac aaaccatacc aaagaattct ttttaagttc actttgaaaa
     7741 tcatttgtaa ctttagtaat aatattatta acattatact ccttattgca taacccccag
     7801 ccagaaggac taaccagtga attaatttct atatctgaaa ttttattgca atgatttaaa
     7861 atagtaaaaa aattataatt aaatggatat ataagtactt tttccataat cccatctttc
     7921 ctttcattag aaaatttaat attgatatcc tagagatttc aaaacgcagt aatctttcat
     7981 attattttct gtagaatgtc taattctgtc acaatcatgt ggttttattt cattttcatt
     8041 acatttagta tcatcaatct tagctataca tatatcacaa taactatagg cccaacaatc
     8101 agaacattgc tcttcatata attttcctat atttaaaagt ttttcagcct tttctatatc
     8161 tactccacta tctaaatttc caatcatacc cattttagaa ctttcactta ctctctcaca
     8221 tggaaaaaat tctccatctg tagttacaaa tattctaaaa gctcctggta tacatggtcc
     8281 accatgatgc cacacatctg gtaactctaa tctaccttca atatttttct catatctaaa
     8341 atcatctaat aaggctcttt ctattcttga taaaggtgac atactctcat cttttataaa
     8401 ttttaatttg ttgagtaaag tcaagaatct atcataactc ttacctaata tatattcatc
     8461 tgatgaaact atttctttat cagaatagtt attattaaga gtggaagcta aaaagtttga
     8521 atcttttaaa gtctcatttt tagatataaa atcatctata gaaatgtaat cattttctga
     8581 atttatcact gtattaaatg taatattctt tttataatat tctggatatt tattttttat
     8641 gtaacgtaca ttttttaata caacatcatg agatccttct cctgtatttg caaattttct
     8701 acttttatca tgaatttctt ttcctccatc taaactaatc atagttgtta tattattttt
     8761 tacaaagaat tctattattt cctcattaaa taaagttgca tttgtagtta gattaaagta
     8821 tatttccttt ccttctccaa ctacttttac atattctact atctgcttaa tcaaatcaaa
     8881 ctcaagtaag ggttctcctc cataaaagcc aacactaact tcatttaatt gactagaatt
     8941 cttaatcaaa tagtcaatac ttctttttgc tacatctata ttcattcttt tatttgtatg
     9001 aactctgttg ctgtatgaac cagaataaat gcaatagtca caacgtaaat tacaattttg
     9061 ggttacttgt aaaataatag aggatagatt attttctata tgatatttta tatacttagt
     9121 ttcagggtgc attgttttac ttaccctttt attttttaga aatccataat taatcaaggt
     9181 attaatttcg tcttctattt ctatgttcca gtcactttct ttttctaaat tatgctcaat
     9241 tttatttaga taattataaa cagcagcatt tacctttaaa atcttatccg tattaacatc
     9301 ataaataaaa tatgattttc cagctttaaa tgtgtgtata aatggttttt gattcattaa
     9361 ttaacctccc tttaatattt atttgcagtt acaaaataaa ttaaaataaa cacccttttt
     9421 gtccataagt tcatcatgtc ttccactttc taacaacttt ccattttcaa gaactacaat
     9481 attgttagtt atcttttttg catgttggat atggtgcgtt ataaatattc caatcttatt
     9541 ttcaaatgtt tttttatata aagaaaggag ttcatttccc gcttcagaat ctaaagatga
     9601 atctggttca tcaaaaatgt acatatcagc atctttcata agagttctag atattgctac
     9661 tttttgccat tcacccatag aaagttgctt cttaccaaac caggttccta aaatagtttc
     9721 taatccatct tcctcataaa tacttggttt caatttagtt tctttaagtt tacttttaac
     9781 tttttcttcc aagttactct tatatacatc tcccatggcg acattttctt ttaatgtagc
     9841 ctcatattta atataatctt gaaacataca acttactttt ctaatgtatt catctttttc
     9901 aatatccttt aaattttttc catttatcaa gatgtcacct tcataatcat cataaaaacc
     9961 taataatatt tttaaaagtg tcgttttacc tgaaccattt tttcctagta tagcaatggg
    10021 atcattttta tttaaagtta aattaatatt ttttaaagaa tactctgatg aatgattgta
    10081 tttatatgaa atatttatta actctatttt atttatatcc cctatttttt caaatatttt
    10141 tatatgttca attgagtctt ctttacagtt ataatctaga aatttaaaca gtaaatctgt
    10201 ataaaaaaga tcttgtatta ctgaactaaa taacgaaaat attgattcaa cattatcctt
    10261 tatagattga actgcttgta tatatgtagt cgcatctcct attaaaatct tctttaaaat
    10321 accttgaatt attataaatc ctataattcc tgcagataca attgaatcta aaactgtaca
    10381 taatagcgta gcaataaaat tctttttagc tatattcata tcttgagata taatatcctc
    10441 ttttaatttt ttataatgat taataagttt agaaccaatt ctaaatacca taatctcttt
    10501 gtaagcataa ccttttgaca acaaataatc tatgtaccag gcctttcttt ctttccaagt
    10561 tctgtttaca ctaacatcat attgttcctt tcctaattta atggaatata atgatttcaa
    10621 tacaggaata acaataacaa ctattattag ccaaagttga aattgtgata atacaacaat
    10681 aagagaaagt gtagatactg attctcttat tattgaaata aggttttcag atagtatagt
    10741 aatattaaat cctttttgag attgagctct atttatcatg tcataagtat tatcatcctc
    10801 aaaatctttt aaactcaaag ttaaagattt ctctaacatc attgtttcaa tatgtttttc
    10861 aaaattttta ttaaacttta ttctataata tccataaaaa ctttgaaaaa ttgaaggaat
    10921 tatatttatg attaaataca taattaacaa aactaatatt tcttttacac ttttcgaaaa
    10981 tgtttgcata ttattaatga tattttgact tactaacaaa gaaatagatg gaacaatccc
    11041 ctgaaaaatt gccataaaca tagagataaa taaatatctt ttatcatgta gataaatcat
    11101 attaaaacaa tttcttacac ctttaaaa
//
LOCUS       DAGQVA010000110        11044 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.110, whole genome shotgun sequence.
ACCESSION   DAGQVA010000110 DAGQVA010000000
VERSION     DAGQVA010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11044
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.110"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(97..1311)
                     /gene="dpaL"
                     /locus_tag="MIV85_003466"
     CDS             complement(97..1311)
                     /gene="dpaL"
                     /locus_tag="MIV85_003466"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBY2962773.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(1925..2462)
                     /locus_tag="MIV85_003467"
                     /pseudo
     CDS             complement(1925..2462)
                     /locus_tag="MIV85_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            complement(2539..4344)
                     /locus_tag="MIV85_003468"
     CDS             complement(2539..4344)
                     /locus_tag="MIV85_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBY2962774.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(4740..5117)
                     /locus_tag="MIV85_003469"
     CDS             complement(4740..5117)
                     /locus_tag="MIV85_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBY2962775.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6022..6507
                     /locus_tag="MIV85_003470"
     CDS             6022..6507
                     /locus_tag="MIV85_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962776.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(6707..7246)
                     /locus_tag="MIV85_003471"
     CDS             complement(6707..7246)
                     /locus_tag="MIV85_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBY2962777.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(7239..7652)
                     /locus_tag="MIV85_003472"
     CDS             complement(7239..7652)
                     /locus_tag="MIV85_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2962778.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(7688..8809)
                     /locus_tag="MIV85_003473"
     CDS             complement(7688..8809)
                     /locus_tag="MIV85_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBY2962779.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            9408..>11044
                     /locus_tag="MIV85_003474"
     CDS             9408..>11044
                     /locus_tag="MIV85_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBY2962780.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKIENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILE"
BASE COUNT         3734 a         1840 c         1292 g         4178 t
ORIGIN      
        1 ttagttttta ttttatttaa agttttcact tatttaagtt tttattttcc ttaaattttt
       61 catttatttg ttaagttttt attttcctta agtcttttat ttactttggc attcaccatt
      121 ccaaactata tctctatatt tatcagggtc agtatctcct tctgtactta ttaataatac
      181 tttagagttc tcatctagtt tcaaagcttc tcttaagtct tttaaatctt cactttcaag
      241 gattgaaact aatgctccag ttgtaactgc tccagattct ccagagatta ctttctcatc
      301 tcctcttaga gggtttccta atattctcat acctttagca gatacccagt ctggtgctga
      361 aacgaatgct gatgaataat tttttaacac ttcaaaacct atagtgtttg gttctccaca
      421 agcaagccct gccattatag ttggcatatc tcctccaaca aatcttggtt ttccatctcc
      481 agcttctgct gatttatagt aacaatcagc ctcatcagcc tctactacta ctgttattgg
      541 gcattcatca tatattgaag caacataccc ttgaactgca ccagcaagtg aaccaactcc
      601 tgcttgaaca aatacgtgtg ttggtctatc tactccatat tcttttaatt gttctatagc
      661 ttctttagcc atagttccat atccttgcat tatccatgct ggtatttctt catatccgtc
      721 ccatgctgta tcttgaacca ttactccatg gtcatcagct tctgcataat cattagctaa
      781 tcttactgca tcatcatagt ttaagtctgt tatactagca tctgcacctt ctcctttgat
      841 tttatttaat ctaaattcag aagaaccttt tggcattaat acaacagatt tttgacctaa
      901 tttattagct gtccaagcaa ctcctctacc gtgatttcca tctgtagctg taaagaaagt
      961 tatttctcct aatttttctt ttatttcttt cgaagtcaat ttgtcatacc ctaactcaga
     1021 tatatctgta tttaatcttt gagctaagta tctacccata gagtaagaac cacctaaaac
     1081 tttaaatgcg tttaagccaa atctataaga ttcgtcttta acatatattc cgcttacgcc
     1141 tagtgatttt gctaagttat ctaatttaac taaaggagtc ttttcatatt gtggaaagct
     1201 ttcatgaaaa gctttagcct ttgcaatctc ttcatctttt aaaaattcaa ttcctttttc
     1261 tttttcctct gatttaggta agttatttaa tttccatttt atttctctca tttattttat
     1321 attccccttt caaatttttc ggtgtcattt taatttttta tctttgtgcc ttatagcaaa
     1381 gcaattaccg tgccaatatt atttattcta aaaacaattt ttttatgttg gaattacata
     1441 cttttataaa atttctttaa agtttataaa ttttgagtgt gaaaaataag atttataaaa
     1501 gaaaaaattc tcatattggg aaatttttat caatacgaga attatcaatt cgagaaatcg
     1561 tttatttatc ttaattcttc ctttattatg ctcttatttt ttatatgtct attgttttgt
     1621 cagatatatt actactttta ttttctataa atatatggct ataaccttct tacgcataaa
     1681 ctctataaat ttatatactt tattacccaa atattcttta ttacccaaag cctccaaaat
     1741 ggcttaaatc ttttcatagc ttcttacaga agtttacatg gtcgtccccc caataagcaa
     1801 aagtgcaata tgtgtaccat tgtgccctac ttgcgactat tgagctgtcg aaattcgcaa
     1861 cttcgcattt atctgatgaa atgcactata caaaatattc ataacatcca caacagagtt
     1921 aaagttacct attcatattc actgtaaaaa tttcttccac aggaaatgta attttaacca
     1981 atcctattga gacaaactca ccacttattt ttttgaactc acgcagtaat acatcacttg
     2041 cccgaaaaaa agcctcactt tcatcatctc cagtaagtgc tattgtgcaa tggggtaccc
     2101 aacgattggg gtggtaccat tcccaaccat ttgaatcaaa atcttgtagt acctcatata
     2161 attctctctg aaactgatac attgctattc attataggtg atacaaacac cgttttagta
     2221 tcattaaaca tgcctactga accaatgtaa gcaggtatta ccttatggtt ttgtgcaaac
     2281 ccctttagct tgtctatgca acaagcctca tccacatcat tgaaacaagc caaagtaaga
     2341 tgaggtcttg ttttccattc taagtacttc gtactaattt tttcatcagc gattttttta
     2401 gataaatcaa aaagttgctt ttccgttttt ttatcataat atagctctat cgcatattgc
     2461 ataataacac ctccaccata aagtaaaaat acctatctat aaaaacacac aaatacctat
     2521 cattttaata ttatattact actgttcctc ttccaatttt ctatatagtg tagccaaacc
     2581 tatgcctaag tcttttgcta tcttcttctt cgtctttgta tctcttccat acttattcaa
     2641 caacttgttt atgtaagtca actctaattc tttaattgaa agtatccttt cttgattctc
     2701 tactatccct ccaactatat catcttcaaa tattatattt acatccttat ttttataaat
     2761 atttccatta atattataat agtttaaaat atctaatgga agcatatctt tatatattat
     2821 tccatcatct ccaaccaaat tcatcatata ttcaactgca ttttccagtt cccttatatt
     2881 tcccggccaa ttatagttaa tcaacatatt cattacattt tcttctattt tatttaactg
     2941 aatacctaat tctaaagaat atttagaagc aaacttcatc attattgcct caatatcatc
     3001 ctttctttcc ctaagaggtg gcaaatttat aggaattaca ttcaatctat agtataaatc
     3061 atccctaaac ttaccttcat ttactaattt caataagttt ttatttgtag cagcaatcac
     3121 tcttatatct aaatctataa gtttatttga cccaattctc gcaaattttc tctcttgtaa
     3181 aactctaagt aactttgctt gtaaaggcat tgacaaatct cctatttcat caagaaatat
     3241 aacaccttca tttgcaagtt caaatttacc tactttccct ccactactag ctccactaaa
     3301 tgcacctttt atatagccaa atagctcact ttcaaggaga ttttctggaa tagcagcaca
     3361 gtttatcgca ataaatggct tgttccatct gctaccttca gcatgtatag ccctagcaat
     3421 tagctcttta cccgtaccac tttccccagt tataagtaca gttgaatttg actttgctaa
     3481 tttcttagtt ctctctttta cttttaacat tgcttctgaa tttccaatta tagactctat
     3541 atcactattt ccccagccac tattcacttt tccatgtcct ttatgattga tatatgtctt
     3601 gtcaaatatt attattttgt cgtattgatt tatatatgga tataccggaa ttattttggc
     3661 atttatatta taaattttgt tatcaatatc aatttctagt aattcatgtc catttgagga
     3721 agattcaaca gatactatat ttactatatt ttctattata tttttatcta tatctaattt
     3781 ttttagagct atattgttta tataagatat tttgctattt atgtctagta ttataacgcc
     3841 tttttcaaca ttttcaatga tttctatcat catatccatt tttctactgc tattttttga
     3901 cgcttcatgt tcttctattt tcatagaaat taaatcgcat atatgattga caaattttaa
     3961 ataattatct atttttgcac ttatttctac ttttttagtt ttatctgtgc taatagcacc
     4021 aattactcct atagttcgat tattatactt tattggaact gctattatta ctttatttag
     4081 gcatttcatg taatgggaac attctataca aagctgatta tcacatatat ccaatacgac
     4141 taattcctga cctgtctgta taacattgtc ataaataaag ccctcagtaa caacgctttc
     4201 atttatcttt gatttataca gacctgtacc actaattctt attaatctat cgtcaactat
     4261 ttcaatatct acatctaaca cactagctac tgtttcagtg tattttatca tttcttgttg
     4321 aaattctttt aatttactta acatagtttc ccccattaga atttaattta ccaaattatc
     4381 agtttagcta tattttaaca tatagtcact ctttaaaata tatataaaac attacttatt
     4441 tatatatttg cgttaaaaca gacaatatta atttataaaa agtttgtttt atatagtaac
     4501 cttaattata atatgcagac aataaaataa atcacaatac aataataaaa aaaagctttc
     4561 ctcatataac aaatatattt ttgacataaa aatatacatt atatgagaaa agctcaatag
     4621 ttaaatattt agatagattt ttatatagac ttttttaata taaacttttt taattgtaga
     4681 ctttttttat tagtttttaa tttttattag ttttgttatt ggttttattg ttataatact
     4741 tataatactg ccattgcttc aatttctaaa actgcatctt ttggtaattg agcaacttgt
     4801 acacatgacc ttgctggtgg attttcttta aaatatgtag catatacttc attaatatca
     4861 ttaaaatcct ttaaatcttt tacgaatact gtagtcttaa atattttatc catacttgta
     4921 ccagcttgtt ctaatattgc ttttacatta tctaaagaag cttttgttgc ttcttttggg
     4981 tcagatacta actcgccagt cttcatatct attggaagtt gacctgatgt agaaactatg
     5041 tttccaactt gaattgcttg agaatatggt ccaattgctc ctggagcttt ctctgtagct
     5101 attactactt ttgacatgac ttcacctcct attattaagt tatatttaca ggaaaataaa
     5161 atttcctaaa caccaatatt aatacgaacc tttagattaa acttcaaatc taaaacttca
     5221 aataatcaat acttagatga ttatgtttat ttgtgtcttg ttaactttta ttaaagcaat
     5281 taacgtgcca aactttattt atatataaaa ttttgtgaag tcattcaaaa tagttacttc
     5341 tgaatttttt cgtaaaaaaa cgctctaaaa ttactttttt atgatgtcaa tttttttctc
     5401 atatctagaa atttaccaac atgagaattc ttgttttgag aatttacaga ttaaagttat
     5461 tttttaacct taaattctga acctcccatg actaaagtca cagggttcct gcttcataga
     5521 attttgcata atcaagttat tacatatgaa agaactatag ttgacaatcc cactattata
     5581 aataataaaa cctttaccca taccttattt accctagtta tcatagagcc tattgaaaat
     5641 ataacagcta aatataataa taaccaaaaa attatcaata tctaccactg ttgctgaaaa
     5701 tccaaaaaac taccttttga tagtattact taacaatcta attaatctca taataaattt
     5761 acaacttata aataaattgt tatattggcc gtatctcaac aactttctcc tttcctagtt
     5821 ttaaatcttt tatagaattg taccacgtct aagtaaattt tcatactatt aagtcttatt
     5881 tctaataaat cattagctct cattctatgc ccaataatgt aagattgcag taattttatt
     5941 gattttaata gttttattta atatacttat attaattatt ttcatatgaa attattattt
     6001 atataggggg atttttttaa tatgagcaaa agtgaattaa cagcagaaac aacagaagaa
     6061 atgttagaag tactaagtgg taaagattat gatattgcat gtcatttaca tgaacttggt
     6121 aaatcattag attgtaaaat tgaaccaaaa acaggtgctc gttcttacaa aatagtatat
     6181 tcaactaaga aaccaaaacg tagcttattt actattgaat gtaatgaaaa aaaatggaga
     6241 gttaaagcaa atctttttca tctaaataca tataaagatg ctgtggagga atgctctaaa
     6301 actattaaag atagtataac taaaactcgt acttgtaaga aatgtaattc aaagtgtatt
     6361 ggaggttctt cgtttgaatt agatggaaag tcttacctga cttgcatagg aagtggtcat
     6421 tattttgcaa atatggaaga aatggattgg aaaaacctag aaaaattaat tactaaagaa
     6481 aataatatta tgcaggaatc tgtatagttt tttaagggta attattaaaa tatatgagta
     6541 acaacagata cttaaatagg cataaaaaaa taaagggtat aataaggata tagaataaaa
     6601 ataaatgata tagcacaaag aggctgtctc aaaatacaga taagcctctt tttattgttg
     6661 aaatgataag aatatattca attttataca attttataca aacatactac gccaacttac
     6721 ccatttcata tgcctgtttc attgccttac ttcccttaat atcacctaca ttccaagcac
     6781 ctacaccata tactatacct ttttccttag aaccatttag acatgatgta aatcctctaa
     6841 atccttctat tgttctttcc atatcagcca cattttcatc tgctgctgta acgataaaat
     6901 agaaatcttt atcacaaatt tcagtatatc tagagcaagt tctatcaatc atagttttca
     6961 tttgcgcatt catagtataa aaataaactg gagtcgctaa aacaatcaca tctgccccaa
     7021 tcattttttc aagaatttct cccatgtcat ctgtctgtga acaatttgct tctttttcat
     7081 aacaagcacc acatccagta caatagttaa tatctttatc ttttaaaaat atcttctcca
     7141 cttgattttt agattctaat accccttgta taaactggtc acacaataaa tcagaatttc
     7201 caccttttct aggactagct gatactatta atacattttt actcataaga tactgcctcc
     7261 attttcttat ttctactgct ctttaatact ttttctttct caataatacc ttcttcatat
     7321 ctatcaatct taaaatttaa tcgttccaaa gttttttgca tttcttctat tctttttgct
     7381 agttggtttc tctgctctat taaaagttct tttctagctt tgatagtact gctcccttgt
     7441 tgaaacatag ctacatactc aattaatgtc tcaatagaaa gacctgcacc tctcatacac
     7501 tttatgaaat taacccactc acaatcttct tctgtaaaag acctaattcc acttttattt
     7561 ctatttacag gtggtattaa accaattcgt tcataatatc gtaaagtatc cgctgaaagc
     7621 tcgtattttt tactaacttc tgaaatcgtc atacatatct tctcctcttg atattgtata
     7681 gattgaatta tttctcaaag gtttctgcta cattctttaa agcatctata attttaatgt
     7741 gttgaggaca gctttcttca cattgtttac attcaataca atctgaggcc tttccataag
     7801 ttttagtata attattatag tagaccatct gtgttgaaaa tccagtatta agagcttgtt
     7861 tttctgcatt gtacaacgca aaatagtttg gaatagcgat attttttgga cagccttcta
     7921 cacaatactg acaggcagta caaggaatta aaattgattc gttgataatc tctactgctt
     7981 catctataat attatattcc tcttgtacga atggtttgaa attttgcata tatcctgtat
     8041 tgtctaataa ttgttccata tttgacatcc cacttaagac catcataaca ttatctttac
     8101 ttgctgcaaa acgtattgcc caagatgaaa ttgacatatc tggattgtag tcattcaata
     8161 atttctctgc tttttctggt atctttgcaa gtgtacctcc ttttactggc tccataacaa
     8221 ttacaggctt attatgcttc tctgccacct cgtagcattt tctagattgt atgctttcat
     8281 tatcccaatc taaataatta atctgtaatt gcacgaagtc tacttctgga tgctcactca
     8341 agactttatc caataattct gcactatcat gaaaagaaaa accaatattc tttatttttc
     8401 cttctttttt cttttcttca ataaacttaa agctatcaaa ttttttagct acttcataat
     8461 gtgacacgcc tatattgtgt aaaagatagt agtcaaaata gtctacacca catttttcta
     8521 attgctcatt aaaaatggtt tcttgctctt cttttttctt taaagccatt aatggaagtt
     8581 ttgtagctat agtaaaactc tctcttttgt gtctttttac tagagattct ctaagtgcta
     8641 tctcactttt tcccatgtga tacacatagg ccgtatcaaa atatgtaaat cccctttcta
     8701 aaaaagtgtc taccatttta tttaaatgtt ccatatcaat agttgtaaca tcattttcat
     8761 cttttattgg taaacgcatt aatccaaatc ctaatttttt tgcctccatt gttttacttc
     8821 cccctttaaa acttgtttgt tttttctctc tactttaact attcttacaa gtatataatt
     8881 cttgtataat tatactttac tacttggagt taacttcaag tcaatagatt tttttatttt
     8941 taagacaaat attataaaaa tacagttctt taatattaat ccattacatg tttctttcac
     9001 cctccaattc tcaaacttca caaactccaa catgtaaaga aatatatact ttaagaaatt
     9061 cagtccatta atattactac aaatactttt tagatatgtt taaaaagaaa tttcacctaa
     9121 aatatttata aaagatttag aaataggtct tgtgtctatt ttaaaatata taaaacagtg
     9181 ataaagactt atttataaga taaaaaatga atagtgtata ccctttttaa aaagtttttt
     9241 cctttttata tttgtgatac aatgttaaat ataaaaagga aaattttgta ttaaagaaat
     9301 cttatttgtt gattttgtaa cttcaaactc agtatcaatt tgattttaag attatatttt
     9361 attaagtatg ctaaataaca aatttttaaa gattgtgagg taaaaatatg aataagaaaa
     9421 atttagctat attaatatca ggtatgatgt ttttttctag ttcttcagca atttttgcag
     9481 acaatactac aaagcaagaa agattaatag gtaaaacaag atatgaaaca gcagtagaag
     9541 taagtaaatt gggatgggtt caatcaaaaa cagccattat agttaatggt aattctattc
     9601 aaagtgcgct ttgtgcaaat ccatttgcta agctaaagaa tgcacctata cttttagtaa
     9661 acaacaacag tattgaaaat tcaactaagg ctgagcttaa aaggcttggt gtagataatg
     9721 tgtacattgt agatagtgga aatagcattt cttctaaagt agaaaatgaa ataaaatcac
     9781 ttaacataaa aataaataaa atagtaggaa acaatatata tgaaatgtct acaaatgtac
     9841 ttaaagaaat agataagata aaaaagatag aaaatgttgc agttgtaaat ggactaaagg
     9901 gactatctga tgcagttagt atagcttctc cagcagcaat acataatatg cctataatat
     9961 tagtatcaga tgaaaacagc aatgatagta gtataaattt cttaaacaat aggtctataa
    10021 aaaaatctta catagttgga ggaaataaga ttttatcaga caatacagta aagaaatatc
    10081 caaacagaga aagaatcagt ggttcagata gaaacaatac taatgcaaaa attattgata
    10141 aattttataa agataaaaaa ataaataatg tatttgtagc taaagatggt attaaccaag
    10201 aaaatgcatt agtagattca ttatcaatag gagtactagc tgctaaagaa aattctccta
    10261 taatgatatc taatggtagc cttgtaaata gtcaaaaaga atttattaaa aataaagata
    10321 tagatgaaat aacacaagta ggaggaggat ataatcaaaa agcatttgaa gatattttaa
    10381 aactaaaaaa tgtgaacata agaaataaaa ctaaaaaaat atctttaata caggctaaag
    10441 aaatattaaa acaagctctt ccaggaagca atattttagt ttgttattat gatgaagatg
    10501 ataatgaata tgactgcaaa gttataaagg ataatatcct atatgagata gaaattgatg
    10561 cctactctgg taaaataata gaaattgaaa aagatgatga cttaaatgat aataatttag
    10621 gtacacaaaa tatatcattg gataaagcta agtctatagc attagatgct attcctaatg
    10681 gtaatttaat ctattgtaaa tatgatgctg aagataacga atatgaggct aaagtaataa
    10741 aaaataagaa aacatatgaa ttagagataa gtgcatttga tggaagaatt gtagatattg
    10801 acatggacaa tgattctgat gatgactttg atgataatga taagaataac tctaatacta
    10861 atgacaacag ttctattatt agtgctgaaa aagctaaatc aataatgcta gataaagtgc
    10921 ctggtgggaa aatagtaaaa tttaagtatg atgaagatga caaagaatat gaaggtgaaa
    10981 taataaaagg aaaaactgaa tatgagataa caattaatgc aattactggt aaaatattag
    11041 aatt
//
LOCUS       DAGQVA010000111        10512 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.111, whole genome shotgun sequence.
ACCESSION   DAGQVA010000111 DAGQVA010000000
VERSION     DAGQVA010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10512
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.111"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(107..295)
                     /locus_tag="MIV85_003475"
     CDS             complement(107..295)
                     /locus_tag="MIV85_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962781.1"
                     /translation="MNYHTKEELVEALRVISSSIINCEKGQKKFSEETSHHTCFKNII
                     EAIYISKSLIMDEISKRD"
     gene            630..1598
                     /locus_tag="MIV85_003476"
     CDS             630..1598
                     /locus_tag="MIV85_003476"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBY2962782.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            complement(1715..2845)
                     /locus_tag="MIV85_003477"
     CDS             complement(1715..2845)
                     /locus_tag="MIV85_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962783.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(2998..3951)
                     /gene="msrA"
                     /locus_tag="MIV85_003478"
     CDS             complement(2998..3951)
                     /gene="msrA"
                     /locus_tag="MIV85_003478"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBY2962784.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            complement(4075..4980)
                     /locus_tag="MIV85_003479"
     CDS             complement(4075..4980)
                     /locus_tag="MIV85_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBY2962785.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFRLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            complement(5351..6943)
                     /gene="hcp"
                     /locus_tag="MIV85_003480"
                     /gene_synonym="priS"
     CDS             complement(5351..6943)
                     /gene="hcp"
                     /locus_tag="MIV85_003480"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBY2962786.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDICGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            complement(7003..7728)
                     /locus_tag="MIV85_003481"
     CDS             complement(7003..7728)
                     /locus_tag="MIV85_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2962787.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSMSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            7893..8597
                     /locus_tag="MIV85_003482"
     CDS             7893..8597
                     /locus_tag="MIV85_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBY2962788.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYTKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            complement(8761..10032)
                     /locus_tag="MIV85_003483"
                     /pseudo
     CDS             complement(8761..10032)
                     /locus_tag="MIV85_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017416360.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
BASE COUNT         3524 a         1749 c         1189 g         4050 t
ORIGIN      
        1 caaatttata attgtatatt attccaatat tttataacat gtatatttac ttattttctt
       61 atataataaa atgtatatta aaacatgtta aattgcaaaa taagcttcaa tctcttttac
      121 taatttcatc cattattaat gattttgaaa tatatattgc ttctataata ttcttaaaac
      181 atgtatgatg agatgtctcc tcagaaaatt tcttctgtcc tttttcacaa ttaataatac
      241 ttgaagatat tactctcagt gcttccacca attcttcttt tgtatgataa ttcataacac
      301 atttactcct ttatttttta atttagagaa acagtatacc tcaatttaat atcattataa
      361 actgacatca ttattattta tacacatctt ttatcactta aatattctaa ctatcagtga
      421 cattacatat tttaataatt attaatatac atataatact ttaatattca ctaatagaga
      481 gtatattaac attgcttttt taaaaatttt agtataaaat catattaaat aaattttctg
      541 aaataataga atattaaaat attcaaaaac agcttttaat aacatctata attttcaatg
      601 tatcgttatt ttagggggag tgatttaaaa tggcaataaa gccaagaaaa atatctattg
      661 taggttcagg gcatgttggt tctcattgtg gatttagttt aataactcaa ggagtttgtg
      721 atgaactctt tatgattgat atagatgaat ctaaatcaaa agctcaagct ttagatttag
      781 ctgatgcagt ttcatatctg ccacataaag tacatataga aaaaggaact ttttctgact
      841 gtaaagattc tgacatagta gtgataagtg ttgcagactc ttcagaaggg cctttacgta
      901 gacaaaacac aactagatta gatttactaa gaccaactat tggaatgata aaatctatag
      961 taaaacccat agttgattct ggctttgatg gtatatttgt agtcatatct aatcctgttg
     1021 atgtagttac aaattatatt tgggaaaaat ctggctttcc taaaaacaaa gtcattggaa
     1081 ctggaacagc tttagattca acaagactta gaaggatttt atctgaagaa actggaatcg
     1141 ctcaacaatc aattcaagct tattctatgg gtgaacatgg agattctcaa atggttcctt
     1201 ggtctcatgt ttcaattggt ggtaaaccaa tcttagacat gataaaagac aacccaagta
     1261 cttatagcaa tttagactta ccatcaatag ttgaaaaaaa taaaaaaaca ggaataagta
     1321 taataaatgg taaagattgt acagaatttg gtataggtac tgctttagta gaaattgtaa
     1381 aagctatact acacaatgag aaaaaagttc ttccagtttc tacattacta gaaggtcaat
     1441 ataacgaaag aaatgtattt gcaggtgttc catgtgttat aggaaaagat ggtattgaag
     1501 aaattattga aatcaatatg actgaatatg agcaaaacga atttaataaa tcttgttctg
     1561 ttttaaggga atatattgca ctttcaaaaa cactttagat tcaatattct ttcttacact
     1621 aaaagcaggt aaatgactta ttgaaaagac ttttaactaa gttaatgttt aaatcatttg
     1681 tacctgcttt taattttaat actaaaatat aaacctattt tttaccatca aattttataa
     1741 ctttactttt tttatttacc tcttgagata acaatccttt tttcaatccc atcaataatt
     1801 ctaagtcttc tggataaaga tttattccaa attcctctaa acttgatact atactattta
     1861 cactcattat tttattttct atcaataatt caactgctct ttttaaatac gttgggcttg
     1921 aacctttcat tttgtctagt ggttcttcta tcaaccagcc ttttttatcc atttcattca
     1981 taagataatt gtattttttg taatttatct tttctagatt atatgctcta aaaatcatag
     2041 cagatatagg tacaatccat tttttcttta gttctacata ataatctaaa tcttctggat
     2101 gagtcaaatc ttttaaaaaa ctctcttttg gcaataaaaa tgcacaggca tactcatctt
     2161 ctgaaaattg cttacttggt attcttaatt cacttgatat tatatatcca agctcacatg
     2221 ccaaagtata atttctaatt gatgctgact ttttgtcatt acccagagat attagatatt
     2281 tagattcttt actaattctc tgtttttgag taaagatagt tgcccctttt ctatctacat
     2341 tcatacctga tattataatc cctttagact ctaacaaact taccatattt actattggag
     2401 tactatttaa atcccaaaac tctctagtct tatatgcaag agattctata tcatttatat
     2461 taatatctga cattactttt ctatttggca agttttcttt tggaaactta atataattct
     2521 ccataaatga atatatttta tgtattataa ttattttttc tctataagaa atctcttcta
     2581 ctctaggtag tttagattga gggttaaagt ggctatcctc tacaacgata tttatatttt
     2641 catttttata aaaatactct tttggaaaat ttaatatatt agataatttt aatgtatttt
     2701 ctatatttgg tacatactta ttttcctcaa aagcttttaa atctttttta tttattttag
     2761 tttctttaga caactgttct atcgtctttg ctctaaaaat tctagctgat tttaatctct
     2821 ttccattaaa gtcttttaaa ttcatttgtt ttctctcttt caaaattaaa ttcttaatct
     2881 attggtataa ataagattac aattaataat ttatcatact attgacaaaa aaacaaaagg
     2941 tgaaaatatt tttttatatt ttcacctttt agataagttt ataataaata ttcctaatta
     3001 ctcaaaaagt tttaaatatt ctccatatcc taaagcttcc atattttctc ttggtataaa
     3061 tttaagagaa gcagaattta tacaatatct taaacctcca agttcttttg gaccatcatc
     3121 aaatacatga cctaaatgag aatttccttt agcacttctt acttcaactc tgtacatacc
     3181 ttgtgagaaa tcacttctct caatgataga tttatctata actggctttg aaaaacttgg
     3241 ccacccacat ccagaatcaa atttatcttt tgaagaaaat aacacttctc cacttacaat
     3301 atcaacataa attccctctt tgttattatc ataatattca ttttcaaaag gtacttctgt
     3361 catatcattt tgagtaactt caaattgtat aggagttaaa gtctttttta actcttccct
     3421 atttatattg tttccatccc aatgactttt tacaaaatta tatcttccag accctttata
     3481 atacatattg tagtttaatg gtcttttttt ataataatcc tgatgatttt cttctgcttc
     3541 gtagaattta gttgctggaa ttatatcagt cactatttta ctatcaaata ttttactatt
     3601 ttccagatgt tctcttgact ctaaagctat atttttttgt tcttcatcat gataaaatat
     3661 agcagtctta tattgagttc ccctatcacc aaattgtcca ccatcatctg taggattaat
     3721 ctgtttccag aagatattta gaagttcatc ataacttatt atatcatcat catatgttat
     3781 ttgaattgct tctaaatgac cagtagttcc tgaacatacc tcttgatatg tagggttttc
     3841 aacatgacca cctgtatatc cagaaactac tttaataact ccatcatact tatcaaaagg
     3901 ttttaccata caccaaaaac atccacctgc aaaagtagca agttttatca ttttcatcac
     3961 tccttaaata aattatactt tatttattcc ctaagaagta acttaataat ctgcatttta
     4021 ttatttttac ctactcaatg aaatcatgtg taaaaataca attgcaaatt gaatctaatt
     4081 tctataaaag ctctttttct ttatccatcc aaaagcatct tttatatcac aattttctcc
     4141 taaagacatt agatattcta atgcatcaca atcatccata gctacatctt tttccatctt
     4201 aggatttaat ctatagtaat tatctccaag aagtttttga gaaaataact gactcatttg
     4261 agaatttcct tctaaggtaa tagatataat tggtaaatca ggttctttat taattatcca
     4321 gtcaatagct ccccattcgg tagtatctgc ctttatactg ttatatacat atccagtccc
     4381 tattgaaaaa agtcttgtat tcttaagtct aaatccacta tcaatggcat gaattataca
     4441 cgctaaactc gggtcagttg ctattattcc tccatcaaca tgacgattat atgttggaaa
     4501 aaataccgga gcagcactac ttgccattgc tacatctaca actttgctag tctttgtaaa
     4561 agaatttggc atattgttat aaaatactgg tttccatgca ttttcctcat ttcctatata
     4621 aaaacttggt atcattacta atttatttaa atcttttaat tctagttcct ctggaaatat
     4681 acttaataaa acttctttta agtttttgtt ttcatacttt ggtctgagta tttctgcata
     4741 acttttatta aaaatatact ttgaattttc aattgagtaa agttctttta tctctttagg
     4801 gcttacacca tacgcaagcc ctagtgcaat tagactccct gtagatgtac ctccaaacat
     4861 atttatattg tttaatagat ttggatactc ttttactatc ctctcaagta tggatatact
     4921 caatgcccct tttaatccac caccatcaaa tgccaatata ttaaaattag aatttttcat
     4981 atacatatac ccccacataa aacaccttat attttaaatt ttaatcaaaa taatttcact
     5041 atagtatata tattttatgc aagttacata ttacaatgtt cctcttttaa tatttaagtt
     5101 acattcaaac ctttaatact taaaataaaa tatataagat attatatatc taagtattat
     5161 aaatttaata caaaaattct taaaagaata tactgaaagc aggtttattt ttcaattatt
     5221 acaaaaaata aataaagggt catctcaaaa ttgatttttt aatcaaattt taagtttaac
     5281 cccttatctt aattgtggca tacttaaaaa tattttaact ataaatatct ttaagtatag
     5341 atatatttat ttatcctaaa atcttcttca tatcttcttc aggagtagat ataggtgtca
     5401 atgcaaattt atcaaccaat atatctaata cattcttaga taagaatgct ggcaaagaag
     5461 gccctatata gatatttttg atacctaaat gaagtagtgt aagaagtata caaacagctt
     5521 tctgctcata ccatgacagt accatgctaa gaggcaaatc atttactcca cattcaaaag
     5581 catttgccaa tgaaactgcc actttaattg cactataagc atcattacat tgtcccatat
     5641 ccattaaacg aggtaagcca catatatccc caaggtctaa atcattaaat ctatattttc
     5701 cacatgcaag tgtcaatata acagtgtctt taggagcttg ttttacaaat tcagtgtaat
     5761 aatttcttcc aggttttgca ccatcacaac ctccaaccaa taaaaagtgt cttatagctc
     5821 cactctttac agcatctact actttatctt gtacagatga aactgtacct cttgcaaaac
     5881 cagtagttaa tgtatctcct ccattaatac cagtcatatg aacatcttct ctatatcctc
     5941 caagttcaag agctttttct attacactag aaaaatcttt atcttcatca atatgaacca
     6001 tacctggata agcaactact tctgtagtaa atactctatc tctataacta tctttaacag
     6061 gcattaaaca gtttgttgta aataatattg gagcaggaat attatcaaat tctttttgct
     6121 ggttttgcca tgctgtacca aaattacctt ttagatgttt atattctttt agttttggat
     6181 atgcatgtgc tggtaataac tcaccatgag tatatatatt tataccctta tctttcgttt
     6241 gttctaataa tttgtgtaaa tcataaaggt catgtcctgt aactacaata aatggccctt
     6301 tctcgatttt catagatacc tgagtcggtt ctggtgttcc ataagtttca gtatttgctc
     6361 tatcaagcaa ttccatacat tttaagttta tttctccagt tttcataact agacctaaaa
     6421 gttcgtcaat agacaagtct cctccaactg ctattaatcc ttcatagaaa aattcattta
     6481 cgtctttgtc tgtataacca agtaccattg catgatatgc ataggcagcc atacctctta
     6541 atccaaataa gattaatgat tttaatgaac gtatgtcctc attatcattc cataaatcct
     6601 tcatatcata gttatcattt ctattacaag ttgttgaaca atctgaacat ctaggtacaa
     6661 gcttactttt ttctacctca gttttttcaa tttgtctttt tatagcttca tcatcaaaac
     6721 ttacattcgt tatagtagtg aatagcccct ctatcataat tttatctgtt tcacttgttg
     6781 gtctattctt atttccaata gttgctcttg aaagaccaat caacactcct gtaagttcgt
     6841 cttgtaagtt agctgtaccc ccctttttac cacagacacc atttatagta caacctttac
     6901 ctcctgctgt ttgttcacat tgaaaacaaa acattttttc cattttttat tcctcccttt
     6961 ttatttatta aaatttatta tatttttcta taattcactt aattaaattt ctccatctac
     7021 aatttttcca tctacagata tagtaactat ttgccatggt atcatttttc cactattttg
     7081 tagagctgtc ttaacagcat ttactatacc accacagcaa ggaacttcca tacgtgttac
     7141 tactatattt ttaatatcat tttcttttaa aatctctgta agtttttcag catagtcaac
     7201 ttcatcaagt ttagggcatc cgattaatgt aaccttattt ttcataaatt tattatgaaa
     7261 atttccatat gcatacgctg tacagtctgc tgctattaaa agacttgcat tctttaaata
     7321 tgatgcatta gttggtacta attttatttg tactggccat tgattaagtt gagaaccttt
     7381 tatctctact atatcattgc ttatagacat actatttgaa acctctctat ttattgactt
     7441 agactgagaa cctggacatc cacatgctaa agttttcttt tgtgctttct ttgcttccat
     7501 atttgctttt actgcagctt catcatattc tgctgcttct ctatactcaa atgaaatcgc
     7561 atttgttgga caagttggca gacaatctcc cagcccatca caatagtcat ctcttaaaag
     7621 ttttgctttt ccatttacca ttcctatagc ttcttcatga caagcttcaa cacatagtcc
     7681 acaaccatta cacttttcct catcaatttt aattattttt ctcatcattt atatcacctc
     7741 ataaaatttt tttaatttaa agtattgatt tcttatatat atatttttaa tacctatatt
     7801 tctttatttc aaatttcttg tagtaggatt tttatatccc cttgctttta taaacttagt
     7861 atagtacaat gaaaacaaat tatcggttgc atatgcaaca aggaagtgat tatttgaaaa
     7921 aatttttaga aaagcatata gacctactta aaaaaattcc tctatttgaa ggaattaaaa
     7981 gtgatgaact tgaagaaatg ttggaatgtt taggtgttgt agataagact tacacaaaag
     8041 atagtataat attctctgtt ggaagtgaag ttacttctat tggaattatg cttaaaggaa
     8101 gtgctcatat aataaaggaa gatatcgaag ggaataggaa tattgtagct gaactcttgc
     8161 ctggagattt atttggagag gtattcgcat gtactagact acataaaagt aatgttacag
     8221 taaccacaac atcttcttgc gaagttttat tcataaagtt taaaagtgta actggtattt
     8281 gttcatctgc atgtgtattt cataataggc ttgttgaaaa tatgctacaa ttaatagctg
     8341 aaaaaaacat tttacttcac aataaaatag aattactttc tcgtaaaaca actcgcgaga
     8401 aattgcttat gtatttttca aaacagatag aacaaacagg tagccaccag tttacaattc
     8461 ccttttcaag aaatgaaatg gctgattttt tatgtgttga cagaagttct atgtcaagag
     8521 agcttggcaa gatgcgagat gaaggcttgt tatcttttaa caaaaataaa tttgaaatct
     8581 tttattttaa aaaataaaat agatatttaa acatatttat ttcaatatat actatattag
     8641 ttgattcaaa ttataaatat catatttgaa tcttaaattt atatttttac ttaaaaagtt
     8701 aataggtatc taatttatta aaattaagat acctattaac tttattaatt aagtgtacaa
     8761 ttagcttatt ttctttgtag taattgctgt tttatctata agccaatctt ttccttctac
     8821 taatcttgaa actaacattg atgatactgt atttccagtt gtatttaata tagtattagg
     8881 aatatcagtt atagtagtta taactgttaa cagtggaatt gcctccactg gaaaaccgaa
     8941 gatgctaacc acgagcatct caccaataag tcagccacct gctacaggag ccataaatac
     9001 tccaacaaca aatacagtta taaataattg acctatcgtt gctggatttg ccattccact
     9061 acctaaaata cctgataaaa atgccacttt tattattact gctaaaactg acccatcttt
     9121 atgtatattt attccaagag gtataactgt ttctgatata tcatcaggaa ctcctatatt
     9181 tttactagct tctaaatttg atggtataca tgctgaactt gaagaagtag ctagtgccgt
     9241 tgctattggt tttatagcat ttctccagaa ttgtctaaac ccttgttttc ctgcagataa
     9301 aaaagcatac agactgtaaa ataataagaa atacatggct gctgttagtg aataaattac
     9361 aaacaccctt acatatcctt gaattatttt acttccaagt tccccaatta ttgtagctgt
     9421 ataacagcct agccctatag gagcataaag catgaatata cttactactt ttaatattgc
     9481 ttccgttcct tctgataaaa gctttcttat tgtatttccc ctatctccca tcatagctat
     9541 tgctgttcca attaaaactg caaatataac taattgtagt aaattactac tggaaaataa
     9601 atctccaaaa tttttaactg taatacttga tactacttgg tctaataacg ttccttttga
     9661 ttctaaagtt tctgcatctt gagtcaccat taaatttttt acacttgata catctaatcc
     9721 tttagacgga ttaaataata atgcagatgt aatacctaaa aatgcaatta caagtgttgt
     9781 tcccataaat actatagctg tacccttcat tatttttcca aatcgttcca tattttttat
     9841 actagcaaca cctgaagaaa cactaagaaa aactaatggt actactatca ttaatagagc
     9901 atttatgaat aaatctccaa atggttttag tattgaagct tttggaccaa gtactaatcc
     9961 tactatcgcc cctactatag tacatgctaa aagtataatt gatgacttat aattttttaa
    10021 aaagtccctc atttatattt tcctttctaa tgctttatat tataaattac cccaaatgct
    10081 aaaaaaatta aagtaaatta tctaatgcgc attaataatt tttgtaattt tccccaacag
    10141 ctactttagc aaatactgga atatatgtca atttctatag tttttttgta tttttaacgt
    10201 tttattaata gttcatatct atatataaat attaataaaa ttctgctttt aaaacttttt
    10261 ttctagatta attttaataa aacaaacaat ataaaaaaat atatataata ttacttaatt
    10321 attttcaaat ttaatacttt gtactttaat ataaaatttt agtatattca ttgtaattcc
    10381 tatactatat aactccataa agttgatttt gtaaacacat atgatacttt gtcaaatatt
    10441 atttttttat gtatttgata ttttgatata cttttaaaaa gaattttcaa atagttacat
    10501 ttctaatttt aa
//
LOCUS       DAGQVA010000112        10350 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.112, whole genome shotgun sequence.
ACCESSION   DAGQVA010000112 DAGQVA010000000
VERSION     DAGQVA010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10350
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.112"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            216..995
                     /locus_tag="MIV85_003484"
     CDS             216..995
                     /locus_tag="MIV85_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBY2962789.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(1305..2126)
                     /locus_tag="MIV85_003485"
     CDS             complement(1305..2126)
                     /locus_tag="MIV85_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HBY2962790.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGNVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEIWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(2801..3619)
                     /locus_tag="MIV85_003486"
     CDS             complement(2801..3619)
                     /locus_tag="MIV85_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2962791.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQVFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            3787..4368
                     /locus_tag="MIV85_003487"
     CDS             3787..4368
                     /locus_tag="MIV85_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2962792.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            4365..4559
                     /locus_tag="MIV85_003488"
     CDS             4365..4559
                     /locus_tag="MIV85_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962793.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(4723..6465)
                     /locus_tag="MIV85_003489"
     CDS             complement(4723..6465)
                     /locus_tag="MIV85_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HBY2962794.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            6894..8270
                     /locus_tag="MIV85_003490"
     CDS             6894..8270
                     /locus_tag="MIV85_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBY2962795.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            8557..9228
                     /locus_tag="MIV85_003491"
     CDS             8557..9228
                     /locus_tag="MIV85_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBY2962796.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            9417..10214
                     /locus_tag="MIV85_003492"
     CDS             9417..10214
                     /locus_tag="MIV85_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBY2962797.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDVNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         3829 a         1249 c         1573 g         3699 t
ORIGIN      
        1 cgattctata atataattaa cactactttt taaatataat caataccgat tctataatat
       61 taacactatt ttttatgcta tataacaatt attgaaaatg atataaatat aatatctcaa
      121 ataatatgaa tataacatct gaatagaggg tgttttattt gtaaaaaata agtttacagt
      181 ttgagcgtat aaacttatgg taaaggagaa taattatgag ttataagaag attgcaatta
      241 taacgggtgc taatagtggt tttggtaaag agtttctaaa gttattaata aatgaagaag
      301 aaataacaga aatatgggca gttgcaagaa acaaggcgag attaaatcaa ttagtagatg
      361 aatttggaag taaggtaaaa attttttcaa aagatttatc aaaaatagaa gaagtaaaag
      421 aaattggtac atttttaagt aaagaaaatg tatgtataaa ataccttata aacaatgctg
      481 gttttgcaaa attctgttca tacaatgatt taagtataga tgaatctatt aatatgattg
      541 atttaaatat tagtgctgtt gtagcattgg gacttatatg tattccatat atgcaaaagg
      601 gaagccatat catgaatatt tcttcacaag catcattcca gccattgcca tatcaaaata
      661 tttatagttc aactaaagcg tttataagaa attatacaag agcattaaat gttgaactta
      721 agagtaaagg gataaatgca attgctgtat gtccaggttg gatgagtaca aatctattta
      781 agagaggtat agttgtagct gaaaaaggga caaaaaattt cccaggcata gtgtctccag
      841 acattgttgc caaaaaagca ttgaaggatg caaagaaaaa taaggatatt tctgtgtatg
      901 gtataaatac aaaatccagt catttattag caaaactatt gccacaaaaa atgatgatga
      961 aggtttggtt aatgcaacaa catattaagg aataagagtt tcggtaatta agtatcagtt
     1021 ggagattcaa tctgttatat attatgagaa gttttgttga gcaaataata attgtgacaa
     1081 aacggcttat ctagtgccga taagccgtct ataatgtata taaaatatat ttttgatttt
     1141 actttattta gatattgaag tattaaaata tgtaggactt gaaattttat aaagataaat
     1201 actatgatat tttgtaaaaa ctgagatatg ttgatattac atagtttaac tatactgtta
     1261 aattgaagtt ttcttatttt gcattatgct tattacttaa tgatttagac tataatttcc
     1321 ataccatcat atgcaaaata aatgttatca agtttctttt ctaattcact gtaataacca
     1381 tatgattttc cccatatttc gtcaatatgt gtaatgataa tctttttaat tctataatag
     1441 tttttaattt caacaatctc atctaaagta aatatttcat ctttaaatgg tgtgtcttta
     1501 agttttgtac catcatttaa tataccatca tcagaaacta gacttattat taaaacatca
     1561 gcatcaaagt acatatcact atgagtaaat ggcttgggat tacagcaggc atatatgact
     1621 tttttttcat tctctttgat aacatagaag gttatattcc tgtctgggtt attgttaatc
     1681 aaatcaatat caaaattatt tatctttaca tgcgaagttt cattaataga aatgcaattt
     1741 ataacattac cataatattt aagacaatcg agattcgttc ggtttatatc ttcaattact
     1801 tcaggaagcg cataaaagcc aattggatta ttttctcctg tgataaagtc acatcctatt
     1861 ttttcgacaa ttctaatacc cttaacatgg tctgggtcat ggtgagaaat tgaaatatgt
     1921 tttacttccg atattttttg tctgttacaa gctactgcaa tatcttcagg tgtgtctatc
     1981 agcattttta tatcatcaat atataaactt ggccctaatc gttcatatct tccgcctttt
     2041 tgtctggctt cttcacatat tttgcatttg caaaatgaac ttggaataat tgacataccg
     2101 ccactaccaa caatttttaa tttcaaagtt attacaccac cttcttaaaa tattagatta
     2161 tataaataat ctacaatcac aactgattaa caaaattatg agttaataaa ttatatcaca
     2221 tgtaaatatg aaagaatagt atgaaatttt tataaacata tattaaatgt ttctcaatga
     2281 aattgacttt gtatatgaac tgaatgactt attcaatatg gataagacat ttttcttgta
     2341 ataagatatg attgtcctat aaggtttatg taattttgat ataatttgat ataatatatt
     2401 gattaacaac atacatgtta ttggtgagca tatttctata gaatggaata tataattttt
     2461 tatatttatc attgtattat tgtctaaaga aagttaaaaa gagtagagca caaaggaatt
     2521 atttgtactt tactctttta ttgttttgtt aaaaaaacta atttatatta gtgattaaaa
     2581 tatatttaac tagagtataa ggatagtata taatcttata attgatttat ctgacaaatt
     2641 aagataatat cctaattaaa ttgtagatat ttatacataa cactaaaagt aatttgttta
     2701 acaaattaag ataatatcct aatcaaattg taggtattta tacataacac taaaagtaat
     2761 ttgtctaaca aattaaaata ttatccaatt aatataaaaa ttacttcttt ttaactggga
     2821 agcatacctc tgttacccaa ttatcaggat tactatcgtt gccagggctt acatgataaa
     2881 tattaaacat aggaccatcc acatcatagt tattatctga tatccaatta ccaatagcct
     2941 cacaagcgtc tgcaacttga ttgaaatttc cattaacaat tgcagttgca gcagtcacac
     3001 ttggaacagt cttaaattta acatgttcag tatctttata ctttccagat acagcaactt
     3061 gtacttcaac atctacataa tcttctttat atccagtatc ataaaaaact gctttagaat
     3121 actttggggg ttcaatttga acattctggt cttttgtctc taaaaatact tgatgccata
     3181 acattccttc gtcttggtaa gttggtataa cccttctaag tgtcatcata tattttggtg
     3241 caaaattctt tatagttaca tcataatttt tcataatatc atttcctcca attcttttaa
     3301 tagtggtttc tatttttaat agttttttct gtgtatcttc taattgttct tttacttgag
     3361 aatggtggat atttagatat tttatgagac tttctttatc gttatattct gtcaaaattt
     3421 cttttataga atacaagcca aagcccatat cttttagtgc atggattctg tttgtagtag
     3481 aaagttggtc tgcactatag tatctatatc cattagtttt attcgtatga gaaggagtta
     3541 aaagtcctat ttcatcataa tgacgtaaca tacgaatact aattttactt agctttgaaa
     3601 aatcgcctat cttaaacatg tttttgtctc ctttataaag gtacttttag cttaatatta
     3661 atataaacca tatcataatg ttagagtcaa ctaaaattat aattaaatta tattgacata
     3721 tgatgaaaaa aatattatac tgaacatgtt cagaaccgaa aatgttaatt gttttggagg
     3781 tctattatga aaagtaatga taaagatgct agagaacgta taattgaagt tacattgaat
     3841 cttttaaatg aagtagatga tattgaggag attacagtta gaaaaattgc tgagcgtgca
     3901 aatgttggag ttggtttaat aaattatcat tttaaaacaa aggataattt gttgagtact
     3961 gccataggag atgtgatgtc aaatataata gcagagctat atgacgatag tgtatatact
     4021 ctaagaccta ttgaagattt aaaaaattta ttaaaaaaat tgtgtgatac tggattacat
     4081 tatgaaaaag tgcttccttt tgtattgaat caatgtataa ccaatggaga tatgcaagca
     4141 gaacttgata ttgtccctat gcttcgtaaa atttttggaa ataaaaaaga tgaaatgagt
     4201 ctaagaatca ttgccctgca aattatttta ccaatacaga tttctgcttt atctacagaa
     4261 tcatttcagt tatacagtgg tataaatata aagaataaat atgagcgaga taaattcatt
     4321 gatattttaa tagaaaatat tattggagag gatgttgatg taagatgaaa attataacta
     4381 ttggttcaag tcttatcact gttttacttt ttctttcaac tatggtttgt gggttctgga
     4441 ttaagaataa taaggtaaca gatgcaagtt ctattaagtt ccatatgaat agtgctattt
     4501 ttacagggat atttttattg atttccacaa tccttttaat tatatatata aaaaaataat
     4561 aatattatta ataaataaag tatcagaaat tataaagaca agagtcttaa aaatttctga
     4621 tactttacca tataatttta ttaaacatta attgtgtgtg aaaaaatatc acttatttca
     4681 atctaatact aaatcttaag agtgagtata aagtattaga aattaagaag cattttttag
     4741 ttcaagtgga ttatctatac caaaataatc atataaagta gagcttattt cctctaaatt
     4801 tccattttgg aaaggtaatt gtaaatttac cttttctacc acatctttaa atccagcatc
     4861 agtattttga tttaaaaaat ccatatatac atcaacagct tttctgtaat cttcttgtga
     4921 taattgccat atctgaagtg atacatcaga tgcaagacca taactcaagt aataaaaagg
     4981 aacttggaag ttatgagata caagtatcca aaaaggagca tttttttctc taagtatatt
     5041 attggaaact ccatattctt cctctaaatc aaaaaacaat ttattgatat catttagact
     5101 catatatgga ttcttgtata taatttcttg aaattcatca taaagacaag catcaataat
     5161 agtatttaaa acaatcgata agtgttcttt ttttatagct tcagattgtt taccaaaaaa
     5221 atcatcaaaa tatttataaa atagaatttc taaagatgtt gaatgaactt cacatacatc
     5281 tatacttggt tgcatcttat tatttaagtt aatactgttg tagtaattat aaaaatgacc
     5341 aaactcatga gcaaaactag taacacctaa aaaagaattg tcccatgtat taaacaagaa
     5401 aggtgcttta tatttattta tataagtagt atatcctcca ggtgatttgt tttttccaga
     5461 agaataatcg tacaagtcat attttttcat atagtcgaag ctctctttta gttttggaga
     5521 tatatcttca agtactttat caaacttcct aaatgagcga tttttatata ctttaatata
     5581 aatagaagaa tcagatggtt tagatgaaat ctctctatat aatggaacta tgtaatcttt
     5641 tacatcttgt ctaaattttt tagcttcttc ttgagaatag tctttgttta ggttcatata
     5701 ggcataatct atataattct taaatccttg cttacttgct atttcagttc ttgtctgtat
     5761 aagttctaag aatatgttac caaatatagg attgtatttt tttaagtaat ctgaataaat
     5821 tttcacatat tcttcagggc taagatttgg tcttgacaag gcttcttcaa agtctacctc
     5881 tataccatct attgatactg tagatttagc taataaatct tcatatttta caactaggtc
     5941 ttgctctttt ttaagcaaac cttcaacttc tttagaatta agttttccaa tgttctttag
     6001 ataattaaat gtatcctttc caagttcttt ttctaattct ttagagaatt tagaagttac
     6061 aaatctatct tgaaagtctt tgtatgacat gtcaacatct actgatttac tcataagata
     6121 cttatattcc ttagagtaaa attcgtctga tgaatctatg ttatttctaa tttttgctat
     6181 agtaagtgta ctgtaaaaat cctgataaat tttatcaact tcattaaata aatttaattg
     6241 ttccttagct gttttagctg ttaaaagttt gtcgttacac ttgttaatgt tttcgcaaat
     6301 tgactgtata ttaggacgct tatattccat tttttcaaaa ggaatagttc ctctaacaga
     6361 atcttttttt gtatcattag tataatttct tatgtatgat gcaaatataa taaaaactgc
     6421 aattaaaatt agaaaaacaa atattttctt cttggattta accataaaaa tcctccaatc
     6481 atggatatag ttattaatta ttttactata ttaaatataa aaaatgcatg ttaagaaaat
     6541 ttaacataaa gatatagata agattataaa taatataaaa aatttaactt caaaaaagta
     6601 tatgaaattt atactggtaa aatgataaat aaattttaag tacaaaatag taaaagctat
     6661 gatagtttta gacctattat atgtaaaaaa tatagatgtt tttggtgcaa tttaaattaa
     6721 aagatatata taaaaattta aaatattcca aacagaaatt ataaaaatta ctatcattgt
     6781 ctttatacaa tatttatact ataatagaat aataatttag aggaaagctc taaaaataaa
     6841 caaattaagg gtcttaacag tagtgatttt atgttaagga ggtataaaga aagttgaaaa
     6901 caatagttag aagacttatt ctctacgcag atggaatgcg tcctactcaa ataatggtat
     6961 ctgggtttgc tgcgattatt gtaatcggag cattgttgtt aacactcccg atagcgtcgc
     7021 agagtggaga gagtataggc ttattaaatg ctctatttac ggctacttca gcggtttgtg
     7081 ttactggtct agttatggta gatacagcaa cttattggag tttatttgga cagatagtta
     7141 taataacatt gatacaaatt ggtggtcttg gatttatgac cgtagccaca atgttttcac
     7201 ttatggcacg aaaaaaaata caactaagag aaagattatt aatacaagag tcattaaatc
     7261 aagctgattt atcgggactt gtaagactta caagatttgt attaataata accataacaa
     7321 tagagggaat aggtgcactg gttttatcaa ctgtctttat tccacaattt ggtttgtcta
     7381 aagggatatg gtatagtgta tttcacgcaa tatcagcgtt ttgtaatgcc ggatttgact
     7441 tgatgggcag tgtaagtggc ccatttacat cgttaaattc ttatgtaaac aactttacag
     7501 tatcaatgac tgtttgcgca cttatagtgc ttggagggct aggattccct gttgtacttg
     7561 atattgtaag aaaaagaaga ttttcaaaat taaatgtgca ttctaaggtt gtattgtttt
     7621 caactgctac acttattttt gtgggtgcat tatttatttt tcttatagaa tttaatcaaa
     7681 aagctactat ggcggacttg cctttaaagg gaaaagtact atcagcaata tttcaatcag
     7741 taacagcaag aactgctggt tttaatacgc ttgatttagc tactttacga gaaagtagtg
     7801 tatttgtaat gataattttg atgtttattg gagcatcacc tgcatcaact ggtgggggta
     7861 taaaaacaac aacactagct gttttaatca ttacagttag aagttttcta tcaggaaaat
     7921 cagatataga agcttttgaa agaagattag ctccatcaac tataaaaaaa tctcttggta
     7981 tatttgtaat cagtatatca gcagttattt ttggaacatt gattatttca ataactcagc
     8041 ctaattttac attagttcaa tcagcttttg aggttacatc agcacttgct acagttggtt
     8101 caagtttagc tggaactcca aacttaaatg ctttaggtaa gattataata ataatcttta
     8161 tgtttatggg tagagttggt tctcttactt tatttatggc tatactttct ggtggtagaa
     8221 gaaagagtca accaatcaga tatgcagaag gtaaaattat ggttggttaa gttaccaagg
     8281 agtaatataa atttataatg gatttagagt agcactgtaa atctgttgat aaaataaatg
     8341 agcctagatg taattatatg aagaaataaa atcgactaac gaacaaaatt aattaatgaa
     8401 ataaaaaaac agggaaataa aatacaaata aaaaggtaaa tcaaaattaa attaatctgt
     8461 gtatataaaa ttatatattg tgtataagtt ttgtatgtgt aaacaattaa tttaagagat
     8521 attatataaa ttgtgtatta gggaggaagt ttcgagatga agcaatatat agtcattggg
     8581 tgtgggagat ttggaagttc agttgcgtct actatgcatc ttttaggaca tcaagtaatg
     8641 gcaatagaca aaaatgaaga ttcagttcaa agtatatctg acaaggtaac ccattcactt
     8701 atagtggatg ttactgatga gcaagcgtta aggtcattag gtttaggtaa ctttgatgta
     8761 gcagtagttg caataggttc tgatataagg gcatctataa tggcgactct tatagccaaa
     8821 gaaatgggtg tagagttgat aatatgtaag gcaaaggatg aattacaagc taaagtgctt
     8881 tataaaattg gcgcagatag agttgtattt ccagaaagag atatgggagt aagagttgca
     8941 cacaatttag tttcagataa tatattagac catattgaac ttgacccaga gtattcaatt
     9001 gttgaaatcg taactccaaa tagttgggtt ggcaagacac ttatagagct tgaattaaga
     9061 gctagatatg agataactgt acttgctata aaaacaggta aaaatataaa tgttacacct
     9121 tctccagatg aggaacttac agccggaagt atcctagtta taatcggtca aaatactagt
     9181 ataacagcga taacatctgg aaataagggg ataattagaa gaagataatt tactatttaa
     9241 tatatattta attgcaatga aagtagatag tatcatataa ttatgaatag ttatatgata
     9301 ctattttttt aatcgaaggt agtatttatt tgtaagatta gataaagaga aattaaatta
     9361 aaagtaagga ggctgtgcta atataaaaat ttataagtta ttagcattta gataaaatga
     9421 ttacaaatat aaacagtaag gataatgaaa agttaaagta tacaagagca ctattaaaat
     9481 caaagaatag gaataaagag tcaaagttca taatagaggg atacagaata gtaatgcttg
     9541 cacttgaatg tatggcaaac cttgattatg tatttatcaa tgaagaattt gaaaataaga
     9601 aagaacatgt aaaactatta gaagatttgg ataaaaaaaa cacaaagata tacaagacta
     9661 ctaataaaaa ctttaaagaa ttagtggata cagaaaatac tcaaggaata ataggtgtag
     9721 tttcatttaa gaaaaaaaaa ttaagtgaaa gtataaataa aaaagataaa tttgtattga
     9781 ttttagacag aatacaagac ccaggaaata tggggactat aataaggact gctgattctg
     9841 ctggagtaga tgccataata gcactaaagg gatgtgtcga tatatacaac ccaaaagtaa
     9901 ttaggtctac tatgggttct atttttgatg tgaatataat tgatgcttca caagatgaaa
     9961 ctgtggacat gcttaaatca ttggatttta atatagtttc aagttactta aatacagaaa
    10021 atttttatga caaaatagat tatggctcaa aagtagcatt ggtgatagga aacgaagcaa
    10081 atggaataaa tgaagaactt gtatcaaagt ctgatatttt ggttaagata cctatatatg
    10141 gtaaagccga gtcgttaaat gctgcgataa gctctgctat actgatgtat gaaataaaaa
    10201 aatacttaat ttaatgtatt gtaataaata taatgtcatg ttataatctt gaattaaata
    10261 gtagagtatc aaaaatagtc aatatatatt aaaaaaataa ttaaattaat tatatattag
    10321 atgtatatta tataaaaaat aattgagtta
//
LOCUS       DAGQVA010000113        10011 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.113, whole genome shotgun sequence.
ACCESSION   DAGQVA010000113 DAGQVA010000000
VERSION     DAGQVA010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10011
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.113"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            664..1572
                     /gene="trxB"
                     /locus_tag="MIV85_003493"
     CDS             664..1572
                     /gene="trxB"
                     /locus_tag="MIV85_003493"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBY2962798.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1662..3485)
                     /gene="typA"
                     /locus_tag="MIV85_003494"
     CDS             complement(1662..3485)
                     /gene="typA"
                     /locus_tag="MIV85_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBY2962799.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3697..3939
                     /locus_tag="MIV85_003495"
     CDS             3697..3939
                     /locus_tag="MIV85_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962800.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            4087..4278
                     /locus_tag="MIV85_003496"
     CDS             4087..4278
                     /locus_tag="MIV85_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBY2962801.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4562..7063
                     /locus_tag="MIV85_003497"
     CDS             4562..7063
                     /locus_tag="MIV85_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBY2962802.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQSMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            7223..7891
                     /locus_tag="MIV85_003498"
     CDS             7223..7891
                     /locus_tag="MIV85_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962803.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7875..9152
                     /locus_tag="MIV85_003499"
     CDS             7875..9152
                     /locus_tag="MIV85_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBY2962804.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9553..9774
                     /locus_tag="MIV85_003500"
     CDS             9553..9774
                     /locus_tag="MIV85_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962805.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
BASE COUNT         3998 a         1123 c         1678 g         3212 t
ORIGIN      
        1 tttttaaaag tttaaaaacc tagattttca tagtgatgaa gctgttttta atgaaagtaa
       61 tcaaaagata actattaaat atctgtaata ttacaatttt atactacact atattacaaa
      121 aaaagtttac aaaactttaa tttgaaaaat gtaattatat ggtatatcat ataaatataa
      181 gtaaatagtg ctaatattta aactattaat cataattggt tcaacaaaag tatatagtta
      241 ataatgttta atttgaagaa attgttagtg tgaaattaca tatatattca aattaaattc
      301 ataaatattt cacataataa tagtatactg taaacaaaag gaggtattaa atatgggaat
      361 agtacttata acagcagcat tagttttggt tatgtatgga ctttcaattc tatcatatat
      421 atcagaaagc aatatattag aagacactgt aaatgataac caataaggtt ttgaattata
      481 taaataagtg agaactgtaa ataaaagtta atttttattt gcagtttttt tatatatatg
      541 taaaataaag ttaattaata aaaaataatg ttttgtttat agtatatatg gataataata
      601 gtaaagtata agaatgatga gaataatata taagaaataa taatataaag agaggtaaac
      661 gttatggtag atatcattgt aattggtgct ggaccagcag gtttaacttc agcaatttat
      721 gctatgagag cagggttaag cgttacagta tttgaaaaaa atatttatgg aggtcaagtt
      781 gcaagtacct ctgaggtaga aaattatcca gcagttcaaa agatttctgg ggtagaattt
      841 tctaataata tatacaatca agcagttgct caaggtgttg atattcagtt tgatgaggtt
      901 gaagagataa atttagaggg aaaagtaaag gttgtaaaaa cttcttcagg tgaacataaa
      961 gcaaaggctg ttattcttgc aaatggagtt gaaagacgta aattaggttg tgcaggggaa
     1021 caagaattta caggtagagg agtatcttac tgtgcaacat gtgatggagc cttttttaaa
     1081 gataaagaag ttgctatagt aggtggagga aatactgcac tagaagatgc tttattttta
     1141 gctaataatt gtacaaaagt gtatttaatt cacagaagag atagttttag aggtgaagaa
     1201 gtgttggaga aatctgtgaa agcaagagag aatattgaga tactttacag tcatggtgta
     1261 gaaaaaatag aaggagaaaa gactgtatcg aaaatagaag taaaaaactt aaagactgaa
     1321 gaaaaaagaa ctatagatgt tagtggtatt tttattgcta taggtcttaa acctaataat
     1381 aaaatgtttg aaaatgttct tgatttggat gaaggtggat atataatttc agatgagtct
     1441 tgtacaacat cagtagaagg tgtatatgta gcaggagata gtagaactaa gtttttacgt
     1501 caaataataa cagcagcatc agatggagct attgcagccg ttcaagcagc taattatata
     1561 aatgttgaat aatataaatt tcaaataaaa atagccatat aaactgaaat aatttttcag
     1621 tactatatgg ctattttgtt aattagaggt aaatgtacgt tttatttacc ttgtctagat
     1681 ttgttatatc ttaatctatc atgttcattt aagaatcttt ttctaagtct tatagaatca
     1741 ggtgtaattt caactaattc atcatcttct ataaactcta gtgcttcttc aagagtaaat
     1801 attctaggag gagataattt tatagcatca tctgaaccag aagcacgtac gttactcatt
     1861 ttcttgtttt tacaagggtt gactaccata tcatcttttc tggaattcat accaattatc
     1921 ataccttcgt aaacttctac accagggtct acaaacatta cagctctatc acttaaggca
     1981 ttaagagaat accccatagt aacaccaggt ccttgtgcta ttaaaacacc atttcctctt
     2041 gaaggtattt ctcctttaaa ttcttcaaat ttttcaaatg aacgaactaa agtaccttct
     2101 ccacgagtag cgtttataaa ttcacttcga tatcctaaaa gaccacgagt aggtgctaag
     2161 aactctattt ttacatagtc tccttctatt gacatagact ccatcatacc ttttctcatg
     2221 tttaattcat ttataatagt accagagtaa acttcaggac agtttacaac aactctttct
     2281 attggttcca ttagttttcc atcttcttta tgcattaaaa cttcaggttt agaaacacca
     2341 acttcataac cttcacgtct catattttca agtagtatag ataagtgaag ctctccacgt
     2401 ccagaaactt tgtatccatc agtagtatca agaggttcaa ctttaagacc aacatttact
     2461 tcaagttcct tttcaagtct atctttcaaa tgtctagttg taacgaattt tccacttttt
     2521 ccaacgaatg gagagtcgtt tactaagaag ttcatagaaa gagtaggctc ttctattttt
     2581 atcatttcca taggtagtgg actatctaaa tcgcatatag tttcacctat agatatatca
     2641 ggaataccag ctataacaac tatttctcca ctagtagctt catcaacttc aacttgtttt
     2701 aaaccttcat acacagaaag ttttgatact tttcctttag atacaacaga atcttctcta
     2761 catatagcaa cttgtgtatt gtttttaaga gtacctttgt aaattctacc tataccaagt
     2821 ctacctacat aatcatcata tgcaagagct gatatttgga actgtagagg ttcattatcg
     2881 taattaggat aagcttcaac gtgatttaca atagttttaa atagaggaga aaggtcttca
     2941 ctatcatcat ccatttcaag tttagcaata ccttgtttag caataccata tattatagga
     3001 aattcgcatt gctcatctgt tgcatttaag tctacaaata aatcgaaaac ttcattaact
     3061 acttcttccg ctctctggtc ttttttatca atcttgttta taaataatat tggttttaaa
     3121 ccgaactcta aagatttttg taaaacgaat ctagtttgag gcattgggcc ttcactagca
     3181 tcaactaata gaataactgt gtcaacagtt ttcataacac gttcaacttc agaagaaaag
     3241 tcactgtgtc ctggagtatc aactatgttt attttgtaat cttcatagtt tattgcacag
     3301 ttttttgaat atatagttat gcctctttct ttttcaaggt cgttactgtc cataacgcag
     3361 tctttaacta cttcgttctt tctaaaaaca ccgctttgag aaaggaaagc atcaaccaat
     3421 gttgattttc cagcgtcaac gtgggctata actgcgatat ttataatttt atgtttttgt
     3481 gacatttttg ttgctccctt cgattaaaat aacttattaa ttatagcaca atatattatt
     3541 aggtacaagg aggaatatat taaattgtat taatatagtt taaattggat aaaactgtta
     3601 gttttgcatc tgaaaattat tctgtttaaa aaaatttttt agacaaataa taaccttaat
     3661 agataaaaag attaataaaa gagtaaagga tgatatatgt tggaagtaac caaaataata
     3721 attaaatatt ttgcaagtga aagtgatact tttgtaaaag aagaagtttg taattttgaa
     3781 gaacttctta agtggtctca taaatttatt gaaggtaaaa agatagaaga tgttttgtat
     3841 ataaagtcta aagaaaacta taaagtaaat gtgattaagt ctttagaaat taaggaattg
     3901 gaaatagtga gaaaacaaca gataccaccg tacatgtagt attaataata tttaaaatta
     3961 atatgtaata ctcacaatag gatataaatg gtatatatgg taataattta tattaaaaaa
     4021 acttttataa agtttatatt tgggtataaa agtattaatt agacattaat taggaggaac
     4081 ttaaatatga taagagtatg cccaaactgt tcaaatgtgg atgtaaataa gctaaaaact
     4141 ttggttggag aagaaaatgt aaagactggt tgtataggtc agtgtagagc atttaaaaaa
     4201 gaagctgttg gaataataga caatgagctt gaaataaagg aaacagaagc agagtttttt
     4261 gaagcatgta aagaataaat tttaaataaa ttataataaa tagagcatct aaattgtata
     4321 agcattaaac aatttagatg ctctattttt atatatacat ttaattatga gtatactttt
     4381 ctattaaata caaataaata taactaatac atttatttat taaaaaaata ttgatttaat
     4441 atacctatag ggggtataat aaaaatatag atttctaaat aagtaattta tcaatattac
     4501 atatcaaaat aaaacgttac aaattagctg aaaatatatt gaaagaaagg aagattttat
     4561 tatgagttca aataaagtgg tagaaagtta taaaattaca ggtatgacat gtgcagcttg
     4621 tgcaaaggca gtagagagag taactaagaa gatggatgga gtatatgacc aaagtgtaaa
     4681 tatagctact gaaaaactta aaatagaata tgataattct aaggttaatt ttgatgatat
     4741 aaagcaggtt gtagaaaaag caggatatgg aattataaag gaagaaagta ataaaaaaat
     4801 tgatatgaaa attgatggaa tgacatgtgc agcttgtgca aaagctgtag agagagtggt
     4861 aaaaaaattg gatggagtag aaagtattag tgtgaatatt gcaacagata aagctaatat
     4921 agactatgac ccatcaaaag taaaattatc tcaaataaaa gcagctattg aaaaagctgg
     4981 atataaacca atagaagagg taagaaataa ggttgatgtg gatgaagata aattgagaaa
     5041 agaaagagaa atgaagtctt tatttgttaa atttatagtt gcaatagtat ttgcagtacc
     5101 tctgttttat atagcaatgg gacctatgat aataaagcct atagggccat ggcctttgcc
     5161 agaaattata aatcctatga caaatacttt taattatgca ttaattcagt taattttagt
     5221 aataccagta atgatagctg gttataaatt ttatataaat gggtttaaat cacttttttc
     5281 tttaagccct aatatggatt ctttagttgc aataggaaca ttagccgcat ttttatatag
     5341 tctatatacg acactacaaa tagccaatgg acaaattcaa agtatgcacc atcatcagtt
     5401 gtattatgaa agtgcaggaa taataatagc acttatctta cttggtaaat atttagaatc
     5461 aaaatcaaaa ggaaaaacat cagaagcaat taaaaagctt atggggctac aacctaaaac
     5521 tgcaatagtg ttagttgatg gtaaagaagt tgaaactcct atagaagaag tagagatagg
     5581 agatatacta ttagtaaaac caggaactaa aatacccgtg gatggagttg taatagaagg
     5641 atatacatca gttgatgaat caatgcttac aggtgaaagt ataccagtag aaaagaatgt
     5701 tggaagtaag gtgacaggag ctagtattaa taaaaatggt gttattaagt ttaaggctga
     5761 aaaaattggt ggagatactg ctcttgccca aataataaag ttagttgaag atgcacaagg
     5821 tacaaaagca cctattgcta aacttgccga tactgtatct ggatattttg taccaatagt
     5881 aattgcaata gctgtagttg catcattatt gtggttttta ataggaggaa aagatatagt
     5941 atttgtactt actatattta tatcagtact tgtaattgct tgtccttgtg cattaggatt
     6001 agcaacacca actgctataa tggttgggac tggaaagggc gcagaaaatg gaatcttgat
     6061 aaaaggtgga gaggcattag aatctgcaca taaagtaaat acagtgatat ttgataaaac
     6121 aggtactata acagaaggaa agccaaaagt aacagatata gtattaaata ataatgtaaa
     6181 agaagaatat cttatcaaga ttgcttcaag tgcagaaaaa ggttcagaac atcctcttgg
     6241 agaagcaata gttaagtatg gagaagagaa gaatataaaa tttgaaaaag ttgataattt
     6301 taaagctata ccaggtgctg gtatacaagt tactattaat gatgaaagta tattacttgg
     6361 aaatagaaag cttatgaatg acaataatat aaagcttgga gatttagaag aaaaatcaaa
     6421 tatattggca agccaaggta aaacacctat gtatatagct gtagatggaa atttatcagg
     6481 tataatagca gttgcagatg tagtcaaaga aagtagtaaa aaagcaatag aaatacttca
     6541 tgatatggga ataaaagttg caatggtaac tggagataat gcgaaaactg caaatgctat
     6601 agcaaatcaa gtaggtatag atatggtttt ggcagaggtt ttaccagaag ataagtcaaa
     6661 agaagttgaa aaactacaaa atcaaggaaa gtttgttgca atggtagggg atggaataaa
     6721 tgatgcccca gctcttgcaa aagcagatat agggatagca ataggaagtg gaacggatgt
     6781 agccattgaa tctgcggata tagtacttat gaagagtgat ttaattgatg ttccaacagc
     6841 aattaaactt agtcatgaaa ctataaaaaa tataaaacaa aacctatttt gggcatttgg
     6901 atataataca attggtatac ctgtagcagc aggaatatta tatgtatttg gaggaccttt
     6961 attaaaccca atgattgcag cagcagcaat gagcttaagt tcagtttcag tcgtatcaaa
     7021 tgcacttaga cttaaaaact tcaaggcata taagagagat tagattaata aattaaataa
     7081 aatgtatcca aaagagctat ctttaaatta aaaggattaa tttacaaatt aagatagctc
     7141 ttttttcatg taaaattcac aacaataaga taaaatataa gtaatatacg aaattttaaa
     7201 taaaatagaa aggattgata gaatgaattc gtcaatactt gtaattgaag atgattcaaa
     7261 tatacaagag ttaatatcag aatttttaag tgcagaaggt tatcaagttg atacagcaaa
     7321 tgatgggttg gaaggtatac aaaagtttaa gcaaggaagt tatgatttag taatattaga
     7381 tataatgatg ccaaacttag atggttatgg agtttgtaaa atgataagaa agtcatcaag
     7441 cgttccaatt atatttttaa ctgctttaaa tgatgaagga gaccaactta aagggtttga
     7501 cttagaatgt gatgattata taacaaaacc attttcattt aatcttctta taaaaagagt
     7561 agaagcaatt ttaaggcgaa gtaacaagac tataaatgac aaatttatag tttttgaaaa
     7621 attaaaatta gatttaaaca catatattgc agagatagat ggagaaccta tagaacttac
     7681 actaaaagag tttaatatat taaaagcttt gatagaaaag tatccacaag ttataactag
     7741 ggaaggtctt ttggatagta tatggggtta tgactattat ggagatacta ggattgttga
     7801 tgcacatata aaaaatataa gaaaaaaaat atcattacca tatattaaaa ctgtaaaagg
     7861 aataggatat acacttgaga aggatatttg ataagtggga aaagttaagt ataaagtata
     7921 agttattttc aataacgaca tcattattaa tagcattagc tttaataata tatctaattt
     7981 tatatttttt attgccatca tattatcatg agtataaaat tgagtctctt caagaaagtt
     8041 tgaaatcttt agtagatagt tcaattcatt tcgatacata tactttagaa gaaagacttt
     8101 attatatggc taaagaccaa aatttggcta ttttattaaa agataaccaa ggtaaaattg
     8161 tatatggtaa gaatgaagta gttattttaa gatatagtaa gtacatgatt aatagtcttg
     8221 aggatgagta tagaacttct atacctatat atactaaaga tgcaaaagat ggtccatata
     8281 ctttagaact cgttatgcca ttacaaccaa ttgacgaagc aaacgaagtt ataagaaaac
     8341 taatgccata catcatatca atagcaatat tgatagcgat tattggagca tatatatatt
     8401 caattgtaat aacaaagcct cttataaaca taatagagag tgagagagaa caggaatata
     8461 gaaggaagga ttttgttgct acaatatcac atgaactaaa aactccaata accataataa
     8521 gtggtcaaat tgaaggtatg atttatagtg taggtaagta taaggatagg gatacttatc
     8581 tgaaaaaatc gtatgagtgt acacaagaat taaaagattt agtaaatgaa atgatagagg
     8641 tttcaaaatc agaaatactt gaaaaagatt tgaaattggt atcaataaat ataagtgaat
     8701 tattaaatag acttgtaaag agacaagtat ttttaataga agaaaaacat atgaaaacta
     8761 ttttaaaaat agaagaaaat ttggaaatta aagcagacca agagagaata actaaggcaa
     8821 tcaataatat aataaataat gccataaaat attctcctga agaatcagag cttataatta
     8881 gactctatga taaaaataaa cgaataagta aaaagacttc taatcaaaga gtggttttag
     8941 aaattgaaaa tactggtgta actatcgaga aacgttattt agaagaaata tttaatccat
     9001 tttatagaat agaaaaatct cgttcgagaa aaactggagg aagtggactt ggactttata
     9061 tagtcagcca aatttttaaa agtcatgggt ttgattatag cataaaaaac aaagaaaact
     9121 ctgtagtatt cacagtagaa tttaaaaatt aattacttat tataaagaat atataacttt
     9181 caataatagt tcattttaaa atcacaaaaa attcataatg aaactgtatt atataaatat
     9241 aaagaagctt aaaaccataa aatacaccaa ctataatgat gagatttcct tacatcctcc
     9301 atataagtca tcattatagt aacccaacaa ttaagttact atgaatttaa aaaataacac
     9361 cgagcatata atctatgctt agtgttattt ttattttgaa ataaaaaata tttaatttat
     9421 tgaaatgtat agatttagat agtttaaact atatttaaga cttaaaaatt ataattgata
     9481 ttacaaataa atatatgtac tttgggaaaa ataaatatag gaagtattat atttacagag
     9541 gaggtagttt tgatggatag attaaaaaga gatatgaaaa atatgaaaga agatttaaaa
     9601 gaaggtgtta aaaagacagc ttatgttatg aaaaatacag ctgaagattt gaaagatgat
     9661 gcacaaggtg ctatggtaaa cttagaaatg aaaaaagatg agatgatgga aagatatgaa
     9721 caaaagaaat tttctaaaga attagagaag caaatgaaga atgaaatgaa ataagctttt
     9781 atttatgaat aacaaattat tgtattcata taaaaagtag ccagtaatat taaatagttt
     9841 atttaaggaa atagactttc taaaaataac tgtattagat ttagaaagtc tatttcaaat
     9901 tagttttata aatagacata aggataaagt agatgttata gaactagatt ttaaaaaata
     9961 gatactaagg ataaaataaa tattatagaa atatgttttt aagaatagtt a
//
LOCUS       DAGQVA010000114         9732 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.115, whole genome shotgun sequence.
ACCESSION   DAGQVA010000114 DAGQVA010000000
VERSION     DAGQVA010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9732
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.115"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            41..535
                     /locus_tag="MIV85_003501"
     CDS             41..535
                     /locus_tag="MIV85_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBY2962806.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
     gene            924..1094
                     /locus_tag="MIV85_003502"
     CDS             924..1094
                     /locus_tag="MIV85_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962807.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESGYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(1571..1760)
                     /locus_tag="MIV85_003503"
                     /pseudo
     CDS             complement(1571..1760)
                     /locus_tag="MIV85_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1922..2272
                     /locus_tag="MIV85_003504"
     CDS             1922..2272
                     /locus_tag="MIV85_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBY2962808.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     SKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            2274..2474
                     /locus_tag="MIV85_003505"
     CDS             2274..2474
                     /locus_tag="MIV85_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962809.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     regulatory      2654..2743
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            2797..2973
                     /locus_tag="MIV85_003506"
     CDS             2797..2973
                     /locus_tag="MIV85_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962810.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     gene            3198..3398
                     /locus_tag="MIV85_003507"
     CDS             3198..3398
                     /locus_tag="MIV85_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBY2962811.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            4033..4845
                     /gene="modA"
                     /locus_tag="MIV85_003508"
     CDS             4033..4845
                     /gene="modA"
                     /locus_tag="MIV85_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2962812.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            4855..5646
                     /locus_tag="MIV85_003509"
     CDS             4855..5646
                     /locus_tag="MIV85_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962813.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            5648..6343
                     /locus_tag="MIV85_003510"
     CDS             5648..6343
                     /locus_tag="MIV85_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2962814.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            6330..7061
                     /locus_tag="MIV85_003511"
     CDS             6330..7061
                     /locus_tag="MIV85_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962815.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            7375..8175
                     /locus_tag="MIV85_003512"
     CDS             7375..8175
                     /locus_tag="MIV85_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBY2962816.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            8714..9430
                     /locus_tag="MIV85_003513"
     CDS             8714..9430
                     /locus_tag="MIV85_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962817.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
BASE COUNT         3746 a         1132 c         1332 g         3522 t
ORIGIN      
        1 aaaatttata tattattaat tttatatgga ggggaaataa atgaaaaata aaaaaggatt
       61 tactctagtg gaattattag tagtaattgc tataatagga atattggcaa tagtagcact
      121 tccagcatta tttaaaaata tagaaaaagc aaagatagct aaacttgaag ctgatataag
      181 tgcaataaaa agtgcgtctc ttagctacta tgcagatgaa tcaaaatata ctgatggagg
      241 aatgatatca tgggtaaaga aagatggaaa aataataata aatggtggct ttaaagatga
      301 cccattagca gataaaatag aaaatttagg tatgccttat aatggttcat atctattaat
      361 gtcatctcct ggtcatgaaa aatatctaga attaagtata cttccagaag gagaaataag
      421 caaaagtggt ctagataaat taaaaagtga ttatggaagt tcaatagaca taatgaacga
      481 gcaaaacaaa atagatattg taataaaatt tttaaatgat aaatcgaata cttaaataca
      541 ataaatttta tttaataatt gctgatgaaa taaacaatct tgtttggaga aatgaaaaaa
      601 gcactcctca agaatagaat gcttagttat aattacagaa gtgtattggc atacacttct
      661 attttttatt atatcacata atttaaaaat acctattcaa gttgttttta aattatgttg
      721 agtaatattc ttgatagttt atacattaat gaatttcaaa aaaataagta ctctttataa
      781 taaaaagtac tttaatgtat gttaatgtcc tatctaataa aattgtaaca tgccttatgc
      841 tttagtatga taattttcat tttctttatt gttgcaactt atactatagt tttgctaatt
      901 tatctgcaaa cacaacttct ttattgcatg tgtatcaacc aaaaacatca gaatacttac
      961 ttaatacata tgcaaaatcg tatctttcat ctatagtatt cttatttgac tatataacaa
     1021 aaaatgaatc gggatatgcc ttttttataa ttgattttcc atttttatca ttagatatat
     1081 tttataaatt ctagcatatc atttgttatt ttctgatatg ctattgatat tttaaatctt
     1141 ctatttgttt tattattttt tacttttcca attatacatt tataggagtt atatttatgt
     1201 gatttatgaa aaaatgctat gcatttaagt tctaattttt tgataataca tctaactttc
     1261 ttttgattaa taatgatacc actgtttttt aatgtggctt ccctgaggca cacatctttt
     1321 ttaaaaactc aagctcatct tttaaaaatt tattttcata ttctaattct tgttctcttg
     1381 ttaatttatt ttttctttag tgtttttgtt tttattcatt atggtcttcc tttcatttta
     1441 gaaaaggcat caacaccact atgtaaaaat ttttattttc atgttgctat aactgtgcta
     1501 ttgtttattc caaaatactt agcgatttat tgtacactat atttagttat catcatatag
     1561 tttataacat ctaacttgaa ccatatagta tagaaaattt tttttatttt tagtgcacac
     1621 tctcctaata tattaaccca tctttcaact tgagaatggt tataaactcc atattgtttt
     1681 actattaaaa tatctcttcc ttctctattc aaataaaatt tagctacttt taatttgaaa
     1741 ttaaaatcat atttagtcat acataaacat ctcaagcagt agatttttgc tctaacaatt
     1801 atggtgcagt acaaatattg tataatactg attttctatt gacaaaagaa tataaaagag
     1861 atatatttgt atcataaaga tataaatata tctcttttaa aattactaag gaggataaaa
     1921 aatgattcag aaaaaatttt ttatgggttt ttgtggtttc cttggatttt taagtcttag
     1981 atatttttca tctggcaatg ttgctgacct tacatatatt ggattttttg cttttttctc
     2041 aaactttatt atatcaaaaa taaatggtga taaagcagat gaaaggtatg tacaagatga
     2101 aaaagcagct atggcattta caggacagct tgctattata gaattattca ttttatggtg
     2161 tattactata gtgtctagga atatagaatt aatgtgtgtt ttactatcaa ttacatatgc
     2221 aatcacttta aatgtttatg ctataaaact ttatatttta gaggaaaaat aatatgccta
     2281 aattcacttg taacctaaaa aaatatagac aattaaaaga attaactcaa gaacaattag
     2341 cagaaaaagt aggagttaga agagaaacca ttatgcgttt agaagcagga aagtataatc
     2401 cttctttgaa attagcaata gatatatcaa aaatagtaga tacacctatt gatgaattgt
     2461 ttatttttga ttagtttttg cattattaaa aatgtgtttt aaatacaaac ttaaattcaa
     2521 tttttaagtc actcctgaca gaggggcttt ttattttttc agataattta acgttcatat
     2581 ataaatttat taatttttca gctagatatg ttgaataata actaattcta ttgtattatt
     2641 aatctgtaga ataaaactaa atcggcaaaa ctagagaaat ttagtgacgc aaagctatag
     2701 ggactaacgc ttataaaata agttatgtca gccagttgcc aaaaagatat tttctttttg
     2761 tttttcatga aagtttttta gggggataaa tacattatgt ttagagataa aatggataaa
     2821 tgtacacata tgttaactgc ttatattggt agttcatatg attattgtga ttttatagat
     2881 acacagttag atgattttat attagagtac ggagaaaaag ttgtggaatc ttgcttgcat
     2941 caagtgatgg tattggtaag taagtataat tagacagatt tttttctaga aaaccctttt
     3001 tagttttatc tacatttaca ttaatatatt ggtaatataa aatgtttaaa tttattttca
     3061 tattaagaat aaataaaaat gttaactaaa aattataatt aaatagacat ttatgttaat
     3121 ctatgataca atagtatttg tggtaataca caagtaaatc aagtatatct tgatataggt
     3181 taataggagt atttttaatg aataatggaa tagtaaaatg gtttaataat gaaaaaggat
     3241 ttggatttat atcaatggaa agtggagatg acgtatttgc tcatttctca gctatacaaa
     3301 cttcaggatt taaatcatta gaagaaggtc aaaaagtaag ctttgatata gttaaaggcg
     3361 ctagaggtcc tcaagcagaa aatataacta tattataata tatagatttt tcggaaagac
     3421 tcttttaaga gtcttttttt tatttacgca ttttgtaaaa aaggaaaaaa taacttcaac
     3481 aaaaaaatac ttaaaaataa tacttagtct aaatactttt tataaaataa atctgacaaa
     3541 aatatattta taaagtatgt acttaaacct acaagtactc ttttaattag aatatatagt
     3601 aatataataa ttttagttgt ggcacatcaa aattttcaac tatctcataa atacatactc
     3661 tttcttttgt attcaattct gatataatac ttttagtaat ttgttaataa aaagcaatta
     3721 aaacatatct atatgtttca atgttctatt ttttcactga aatataataa atataaaatt
     3781 agttaaaaag taaaaaatct acaataagtt aatttgattt aagtttttaa atttaaaata
     3841 ctttaaagta ttaataaaaa ttaaaaataa aataactacc tatggaaatg acattatgaa
     3901 tagatttttt cttaactata cataacaaaa cataacaaaa cattataaaa cataacaaaa
     3961 acttagacat cgttttctta gtatgatata ctaaaaaaga atttacacta atttaataag
     4021 ggggaatatc ttatgtttaa aaaactttca gtactagctt tagctatgat tatttcatta
     4081 agtattactg catgtaattc taaagaaaac aaagctaatg atgaatctaa tactaaagtg
     4141 acaacagctg atgattcaaa agaaaaagag actctttttg tctattcagg ggcaggttta
     4201 aagaaaccaa tggatgaaat agcaaaaaaa tttgagaaag aaaataatgt caaagttgaa
     4261 tatagctatg caggttctgc acagctaata gctcaaattg agacaagtca caaaggagac
     4321 gtatttattg ttggttctga accaatttat tcaaaggcct ttgaaaaaga acttgtaggt
     4381 gaacataaaa cggttgcaca tcatacacct gcaatagttg tacctaaagg aaatccagct
     4441 aatattcaaa aattggaaga cttaaataaa gatggagtta aacttatttt gggagacaaa
     4501 gagtctaatg ctataggtaa gactacacaa aaaatacttg aaaaaaataa tttaaaatct
     4561 ataaatgata atgttgtctc tacagctgca actgtaaatg aaatgattgt acagttaaca
     4621 tcaagtaaag ctgatgctac aatagccaca aaagattcgg tctttggtaa tgaagatgta
     4681 gaagttatag aaattgccca agataaaaat atagaccaac tcatatcagc aggaatcgta
     4741 aactatagtg ataaaaaaga tttagctaat aaatttataa attatataga gtcagacgaa
     4801 gctaaacaga tatttaaaaa atatggtttt gaacctgtta agtagtgatt aaacttgaaa
     4861 aataaatttt ttactactct acttactgga ttttttgcta tagtcttttt gtttattgta
     4921 tcaccacttc ttatgttaat cattaaaggg ataagttatg ttcctatatg cttaaaatca
     4981 gtggaagtac agtatgcaat aacacttagt attaaaacat ctttaatatc tactatagta
     5041 tgccttttat tagctattcc agtagcatat tttttacata ttactaaatt accatttaaa
     5101 aaactgatta tacagataat aaatctccct atgtctcttc cacacttagt atcaggaatt
     5161 gctcttttac ttttgtttgg aagaatgggg attggagatt ccatttataa gatttttaag
     5221 cttgatttta tatttacaaa gcaaggtata gttttagcac aaatatttgt aaatcttcca
     5281 cttactatta aaatacttca cacttcatta aatgaaagta atgaaaagat gatatttgtt
     5341 gcacgtaccc ttggatgtaa tagttgggaa gcatttagat ttataattct tccaaatcta
     5401 aaaactggaa tcatatctgc aactgtaatg acttggtcaa gagcacttgg tgaatttggt
     5461 gcagtagcta tgatagcagg ttctacacgt atgaaaactg aaattattcc tacatctata
     5521 tatttaaata tgtctactgg tgatatagac attgctatcg gaatagctgt aattttgata
     5581 tttctctcac ttacatgctt gatgcttttt gagatatttt ttaatagaga ggttgataag
     5641 aattaatatg ttaaaaataa aaaatttatc tcttgattta cctaatttta aattacaaga
     5701 aaatagttta aatattaata atcatgaata ctttgtttta ttaggagcta gtgggtcagg
     5761 taaaactcta tttctagaaa cattagcagg aagatatcca tctgctaaag gaaatgtatc
     5821 atacaaagaa aatttaatat caaacttacc tccagaaaat agaaatatag gatttgtata
     5881 tcaaaatttt gaattatttc caaatatgaa tgttgaagat aatataaggt ttccacttaa
     5941 attgagaaaa atacctatag atgaacagat tcttaaggct aaccacttgt ctaaattaat
     6001 gcagatagaa gatataaaaa ataggtatcc taaaaattta agtggaggcg aaaagcaacg
     6061 agttgctttt gcacgtgcct taatagctga acctgatata ttacttttag atgaacctat
     6121 gagttcattg gattatatta caaaaaaaca tataagcaaa attttgaagg atgtctacat
     6181 aaaatacaaa ccaacagtga ttcatgttac tcatgatatt tctgaagcaa tgttttttgc
     6241 tcataagata ggaataatga acaatggaaa aataaatcat atttttgatt taaatgaaga
     6301 aataaaaaat aaaggagaat cttttttcta tgaatatatt tgatattttg agagattatc
     6361 tattagtaca agtcgataaa tataatttaa atatggatat gataagtatt gtgtccaaat
     6421 ctctatcttc aaaagaagca attggaaata ctaagcgtaa agatttccca attatagttg
     6481 gtaaagaaat aatgcttgaa gctgacttta aaggagctaa aggacaagca tttacttcta
     6541 ctccatctac atttgaaggt tctttaaaag acatattatc attagattta catgacaatt
     6601 ctcatgatag aagtcttttt atagcatcat taaatgcagt tatgaaatac ttaggcaaga
     6661 cggatagaac cattcattgt aaaaataacg agccagaggt atgtgcaaaa aaattccctg
     6721 agtttataaa aatggaattt ggtaatccaa aagtagcaat tataggatat caaccagcca
     6781 taattgataa tattaaggac tttttcgaaa caagagtatt agatttaaat cctgaatttg
     6841 tggatactat tcaatataat gttaagattg aagatggtat acgagattat gaagatgtaa
     6901 tatcttgggc tgatttagtg atttgcacag gaagtacatt atgtaataac tcaattataa
     6961 attttctatc acttaacaaa ccagtttact attatggaac tacgatagct ggtgcatcaa
     7021 atattttagg tttaaaaaga ctctgttttt gtagtaaata agcaatcata tcatcaagga
     7081 gtacacaaat atatatgtgt actctttaaa tttaaaaagt tattactttt attctaagta
     7141 ctaaagtaaa attctattaa aatgaatccc gaataaatgt acaatccctt taaatctcaa
     7201 ttcctatcaa tcattaatat tttgattagt cttatacata aatgttttct ttattttaaa
     7261 ctaataaaaa aattttattc cattaatcta ctctatattt ttcagcattt aagaaataat
     7321 ttttagtact ttgtttgata atataactaa gacaaccttt caggagatga ttaaatgaca
     7381 tttaagaata aaaaatttac tataaataaa tataaaattc tatctattat tctagtttta
     7441 tgtttgattt taaccgcttt tagtagctat gtgaattata gtcataaaaa atttaaagat
     7501 tatgttgtct tctatgttca gcatcaagat gatgaagtgt tgtgggctgg gagtgctatt
     7561 gttaatgcta taaaagaaag aggaaaaaat catgtatttg tggttttagt atctactgga
     7621 tgtggtatat ccgtctttga taaatataaa aaatatgaaa acctaacaaa tatacaaaaa
     7681 tcagaatata gaaatagaga atttttagct tctcttaata gccttggtgt aataagggaa
     7741 aatataatat tattaccaga aacaaataca aatggtaata ctgacttcaa ttacatggaa
     7801 aaaattgctc ttacatttga agaaaaattt aaaaatgtaa ctcatatagc acatacttat
     7861 aaattagatg accatttaca acatttaaaa aatggttctg ttatccaaaa tttatataat
     7921 gctggtaaaa taaaagatgc taaatatttt gtaaaaccta aatttgctga taaaataact
     7981 tttaataata agatagttta taaagctcat tctactgagg actatgaaaa ggttaaaaat
     8041 gcctgtcaac aatacaaaat tgttgatgaa ttagaatata gagaaggtat tggctataag
     8101 tctgaccata aatcatttga taagttatta aataataaag atgttcctgc tatacttcat
     8161 acacctaatt tataagaaat atttattctt taatttaagt tataaaaagg aaattatttg
     8221 agattttgtg atatagcact ttttgtgcta tactactttt tctcatacaa ctattaccca
     8281 tatctaattt catcatctct taaaatatat aaagatatca tcattaaaac ctataagcct
     8341 tattaaatgc tttatacata cctacattaa actacctgtt tatattaaac tacattaaaa
     8401 taaatatttg ttataaattc ttaataatta tgaaactcat ttgttattta tatttgttaa
     8461 tatatgttta aacctaaaaa attaataaac caaaataaca taagaagtgt gatagattac
     8521 cctagatatt ttcataaact tttaccttca gattaatatg ggcgtctata cttttaaatt
     8581 tactatatgc attgacaata tattaaaagt actagttttt atttcataat gaacgggctt
     8641 actgttttct aatacctctt tttggtataa aataaaaatt ggttaaaaat aaaatttcaa
     8701 gggggttaat aaattgaatc aaaatatatt ggttgtagat gatgatagag agatagttga
     8761 tgctatagag ttctatttga gacctgataa ctttaatgtt ttaaaggcat atgatggact
     8821 tgaagcattg gacatactaa tcgaaaatga tattaaatta ataataatgg atgtaatgat
     8881 gcccaattta gatgggctta aaactacact taaaataaga gaaaaaagga atataccaat
     8941 aattctctta tctgcaaaat cagaagatat ggacaaaatt ataggtctta atatgggtgc
     9001 tgatgactat ataactaaac catttaatcc actagaactt actgctcgag taaaatctca
     9061 acttagaagg tatataaatt taggtgattt tagtaataca aataactcaa atgatactaa
     9121 ttatattcta aaaagtggtg gcctagagct aaatacagat acaaaaatag tttctttaga
     9181 tggtgaggaa attaaaatga caccacttga atataaaata cttacacttc ttatgtcacg
     9241 aaaaggtaaa attttctctt ctcatgagat ttatgaaaat gtctggaatg aggatgctta
     9301 tagttgtgag agaactattg ctgttcatat tagaagaatt agagaaaaga ttgaaattaa
     9361 tccaaaagaa ccaaaatatt taaaggtggt gtggggcatt ggttacaaaa ttgaaaaact
     9421 taattattaa tgattctaaa gcaaaattta ttttattatt attactgttt ctattagttt
     9481 ctatattatt tgaagcagtt tatgatttga ataataactt ttctaatatt aattattatt
     9541 atagagagtt tgctctccct tatttttatt ttttcggtac tcctgtacat ttgtcaaaag
     9601 tagaattaga gtttgtctgc ataggtatta tattatcaag ttttttattg actatactat
     9661 gttttacatt gtataaaaaa aataaacaaa ctaaagtcaa attcttagag aatgtcataa
     9721 accttttttc ta
//
LOCUS       DAGQVA010000115         9353 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.116, whole genome shotgun sequence.
ACCESSION   DAGQVA010000115 DAGQVA010000000
VERSION     DAGQVA010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9353
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.116"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            393..1598
                     /locus_tag="MIV85_003514"
     CDS             393..1598
                     /locus_tag="MIV85_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBY2962818.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="MIV85_003515"
     CDS             complement(1669..1890)
                     /locus_tag="MIV85_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962819.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="MIV85_003516"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="MIV85_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBY2962820.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="MIV85_003517"
     CDS             complement(2643..2993)
                     /locus_tag="MIV85_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBY2962821.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="MIV85_003518"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="MIV85_003518"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBY2962822.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="MIV85_003519"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="MIV85_003519"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="MIV85_003520"
     tRNA            complement(5068..5159)
                     /locus_tag="MIV85_003520"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="MIV85_003521"
     CDS             complement(5160..5615)
                     /locus_tag="MIV85_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBY2962823.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="MIV85_003522"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="MIV85_003522"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBY2962824.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="MIV85_003523"
     CDS             complement(7666..8547)
                     /locus_tag="MIV85_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBY2962825.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="MIV85_003524"
     CDS             complement(8559..9068)
                     /locus_tag="MIV85_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBY2962826.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9194..9310)
                     /gene="rrf"
                     /locus_tag="MIV85_003525"
     rRNA            complement(9194..9310)
                     /gene="rrf"
                     /locus_tag="MIV85_003525"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2982 a         1642 c         1002 g         3727 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttaattttt ttatttatca tgtattcttt atctttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt gtcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa gcttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgaa ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaagatattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 tccttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggctc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ctacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatgatact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatttcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataaca tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctacaataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctcttttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttca ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctacttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcgccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tatttgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt tttttaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa taatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctacatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tatcgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatccct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtagc
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaattgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta agaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaagtata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 tagacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggcgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta caataacatc ttttataata ccacctaaat ctacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaag actacgtggc tacgtcctac tctcccaggc agtttcccac caagtaccat
     9241 cagcgctaga gagcttaact tctgtgttcg gaatgggaac aggtgtatcc tctctgctat
     9301 tgtaaccaca taatctttat gcttaatatt tctattaagt ttttaataag ttt
//
LOCUS       DAGQVA010000116         8646 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.118, whole genome shotgun sequence.
ACCESSION   DAGQVA010000116 DAGQVA010000000
VERSION     DAGQVA010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8646
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.118"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..422)
                     /locus_tag="MIV85_003526"
     CDS             complement(<1..422)
                     /locus_tag="MIV85_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2962827.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWANE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETQDLINEIKDKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKYESTENG"
     gene            complement(480..1250)
                     /locus_tag="MIV85_003527"
     CDS             complement(480..1250)
                     /locus_tag="MIV85_003527"
                     /inference="COORDINATES: protein motif:HMM:NF016362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HBY2962828.1"
                     /translation="MSLDTLKEYLSICDDNLIWEPFYDDSMLLDEFSNYIKEIELSKE
                     WNKSKNHEKGKILEQLVRFIMSRFTILSDISVNKSTTDNELDVFVKFNDNIPIPFLCN
                     IKSKIVCECKNWKSRKVDVGMVSKLAEICNKNNAGLGIFISLNGLTGKGWQYAEGKRR
                     KLYLSDKMPIISFTVDEITKLKYKRYNLLTMIKCKMQALIDEMEFAGGELRLLESELG
                     FIDCLNENIESLKMLGLITEVEYNNIKVRINHRYDIVN"
     gene            complement(1255..1641)
                     /locus_tag="MIV85_003528"
     CDS             complement(1255..1641)
                     /locus_tag="MIV85_003528"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962829.1"
                     /translation="MMLYEKLENISILLGNQSKAKSIIEELEKLMKSDIITPRLLARK
                     TKVTLLEATRVLEFLVKENELEFFIVVECSNPDSVYENEIGHYKYFTSIKEFNAFSKG
                     QECPICGCGYKYNFEDTKIGFRRLEK"
     gene            complement(1586..2773)
                     /locus_tag="MIV85_003529"
     CDS             complement(1586..2773)
                     /locus_tag="MIV85_003529"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962830.1"
                     /translation="MLNEKNLKNIKNILQMVQMKHLKDFENWGINKRKKETAINSLIN
                     IIQNDGEKLDYFKEWISIFTIDGHNNYYVFNYNDSDLELEDLKNIVEDIVSENLLEID
                     TSDLEETKVIYKKNDVINKRLIIRFISPALISCKNENENGNIESGLEKTFYFATLFLD
                     LSLKQIIVSIPHTVGIKSIDNIEAKARDFSEIAKYYVSKLEDLLTTYNIQIEKYNDWI
                     YDATYELAEEGSAHNNPEINKKYEENIDKIDEFAKKIAIASGITDKAIIENFKEGVGI
                     LYENILIDEFGVVEDENQYSTFVQNGDGVNSYCRVGSKTATLKSGKGHAIAKTSRNNE
                     DVKNLGVMKSFNGTLSRFLIEVLDKELYLIRTDTSKFIEERVIYDVIRKVGEYKYTFR
                     KSE"
     gene            complement(3262..3468)
                     /locus_tag="MIV85_003530"
     CDS             complement(3262..3468)
                     /locus_tag="MIV85_003530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962831.1"
                     /translation="MNRFEGIYSFAEATKLWDLKDSTLRKAVATGKLVENIDCKKFGR
                     DWVVTIEAMEREYGKLNNIMKDLD"
     gene            complement(3890..4390)
                     /locus_tag="MIV85_003531"
     CDS             complement(3890..4390)
                     /locus_tag="MIV85_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962832.1"
                     /translation="MASKVKKEFFMATKKHLENYKQLHINIESLKLQIKNLKEFHLGD
                     FMQGLSYDSIPISKTNSISNQVENELINLEEKIIEKQIELYEMEALKYTIDVSISNLK
                     PIHKQIIRYRYIEGLEWSLIVDKVYLEERQLRERANQAISSISIALFGKKALIEQEPL
                     FKMLDL"
     gene            complement(4409..4825)
                     /locus_tag="MIV85_003532"
     CDS             complement(4409..4825)
                     /locus_tag="MIV85_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBY2962833.1"
                     /translation="MSKYNNKKIVIDGIKFDSKDESEYYLYLKEKKENGEIKDFGLQQ
                     KFELQPKFKKDGKSYRAITYTIDFAIYKWNGEVVYIDVKGYSTQQGELRKKLFDYKYQ
                     DKKLIWIAKSKKYGVDGWIEYSELKKKRKENKKKVA"
     gene            complement(4852..5049)
                     /locus_tag="MIV85_003533"
     CDS             complement(4852..5049)
                     /locus_tag="MIV85_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962834.1"
                     /translation="MNKFQKAVSQMVKQEEKENLLQGYENCIVGRSISSSIRRYVKGF
                     EKFGYSVHEVYEFINDINKYE"
     gene            complement(5328..5777)
                     /locus_tag="MIV85_003534"
     CDS             complement(5328..5777)
                     /locus_tag="MIV85_003534"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962835.1"
                     /translation="MSLIKYRGYDFENEKWIYSETIKWSDAVDCLFMLKEDCEWQRVS
                     NIGVFSKCWSGNNEEIYEGDILKEPYNTKNKYEYGIVRQENYALELYVEWHYLKQFEG
                     KWEEITSKATIMNSKKYVVVGNECENLEEIKKEFLERKEMLENEHLG"
     gene            complement(5895..6260)
                     /locus_tag="MIV85_003535"
     CDS             complement(5895..6260)
                     /locus_tag="MIV85_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962836.1"
                     /translation="MLKVEKYFSGSLGTNIIDDDPTCRNYLALYCCVHGVRKNGELIF
                     PTCEKMLIEFNVDKNRKKKKKGSKVKLINAKTGEEKIFDSIDSAACFLRLQSQAVYQT
                     IKKKTKTRSGWKAEYIKEE"
     gene            complement(6274..6531)
                     /locus_tag="MIV85_003536"
     CDS             complement(6274..6531)
                     /locus_tag="MIV85_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962837.1"
                     /translation="MIIIRSQDKTDLVKADWINVDKECVYAMFGDMDNFKKIGEYEDE
                     KRAIQVLDNIQRFIEGGTRTDSIDSYKVRSYRNRIFQMPVK"
     gene            complement(6518..6703)
                     /locus_tag="MIV85_003537"
     CDS             complement(6518..6703)
                     /locus_tag="MIV85_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962838.1"
                     /translation="MSRTAICSVCGEFLVESYDDQFTNTKVMDLHGREFVIVICKSCL
                     EELLRKCDDGGIRDDNN"
     gene            complement(6773..7180)
                     /locus_tag="MIV85_003538"
     CDS             complement(6773..7180)
                     /locus_tag="MIV85_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBY2962839.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKGKPIYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            complement(7197..7370)
                     /locus_tag="MIV85_003539"
     CDS             complement(7197..7370)
                     /locus_tag="MIV85_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBY2962840.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKIAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            complement(7430..8380)
                     /locus_tag="MIV85_003540"
     CDS             complement(7430..8380)
                     /locus_tag="MIV85_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBY2962841.1"
                     /translation="MNFNNETYFHINFDDPFTRVPNTILDNENLSYSAVGVVTQMLRF
                     QRSGSHKVYAKSLISYRKDSKTKVSNALKELMQEGFVIRTQIRDEKGQMKGYRYDIFD
                     TPQNVNSESVEMTESQPCAVFPTPVKPEAGKTEVGETGSRQNRGREIGNIKENSIKKK
                     IGLKENDVITTVIAEQSEKNKTVCIKKYYESYIGVITPNNFLQLLTYLDDGMEADVII
                     RAIDEAVGSGVKNYKYVKTILNNWIEAGVKTNLELTEYQNEFERKKKNKQEKKQSNHK
                     NVNTPNVSKNKFHNFNETFTQYSPDELDDIIKKSQKVKFK"
     gene            complement(8389..>8646)
                     /locus_tag="MIV85_003541"
     CDS             complement(8389..>8646)
                     /locus_tag="MIV85_003541"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962842.1"
                     /translation="IQLLNITENDTFDATSGKNEAKSNSNNRILTDKQLSRLYAIASN
                     ANVNKESLKEKVFKRFGKEIKDLTKQEYDTICNAYEKQNQE"
BASE COUNT         2513 a         1654 c          845 g         3634 t
ORIGIN      
        1 ccattttctg tgctttcata tttctttaat tccttaatca tttcttcctt gtctttaaca
       61 tacattatct tttgtgctct tattattgct gcatattgta ttgttatctg ttcccaaaga
      121 atatcaaatt tatctttatc ctttatctca ttaattaagt cttgggtttc ttcaggtaag
      181 tattttgaga agaaaccaaa tttttcagca ttcttatttc caggaggacc agtggcattt
      241 ttattaccta tgggtgcacc tcttttattt ttaggtgcac ccttcttttt ctcattagcc
      301 caattgtatc tttttatcca tgactttaaa gtatttaaac taatgtcata ctttgctgat
      361 atttcctttt gtttcatacc ttttaggtaa tcttgtttta ctttttcttt cacatcttgc
      421 acaccaccac ctcgtttgtt tgtcgttttg ggaataaaaa aagaactcgt ttggagttct
      481 cagtttacaa tatcatatct atgattgatt cttactttaa tattgttata ttcaacttcg
      541 gttattaaac ccaacatttt caaagattct atattttcat ttaaacagtc tataaatcca
      601 agttcacttt ctaataatct taattctcct ccagcaaatt ccatctcatc tattaatgct
      661 tgcattttac attttatcat agtcagaaga ttataccttt tatactttaa tttcgttatt
      721 tcatctactg taaacgatat tattggcatc ttatctgata aatataattt tcttcttttt
      781 ccttcagcat attgccaccc cttacctgtc aatccattta aagaaataaa tatgcccaat
      841 cccgcattat ttttattgca tatttctgct agtttagata ccattcctac atccactttt
      901 ctacttttcc agtttttaca ttcacatact atttttgatt ttatattaca taagaatggt
      961 attggtatgt tgtcattaaa cttaacaaaa acatctagct cattatctgt tgtagactta
     1021 tttacagata tatcacttaa tattgtaaat ctagacatta taaatcttac taattgttct
     1081 aaaatttttc ctttctcatg atttttagat ttattccatt ccttagataa ttctatttct
     1141 tttatataat tagagaattc gtctaatagc atactgtcat cataaaaagg ctcccaaatt
     1201 aaattatcat cacatatgct tagatattct tttaaggtat ctagactcac tgtatcactt
     1261 ctccaatctt ctaaagccta tttttgtatc ttcaaagttg tatttataac cacatccaca
     1321 tattgggcat tcttgtcctt ttgaaaaagc attgaattct tttatcgaag tgaagtattt
     1381 atagtgacct atttcatttt catatacgct atctggatta gaacattcaa caacaataaa
     1441 aaattctaat tcattttctt taactaaaaa ttcaagaact cttgtagcct ctaaaagtgt
     1501 aactttagtt ttcctggcca gcaatcttgg tgtaatgata tcactcttca ttaatttctc
     1561 taattcttct attatagatt ttgctttact ctgatttcct aaaagtatac ttatattctc
     1621 caacttttcg tataacatca taaatcaccc tctcttctat aaatttagaa gtgtctgttc
     1681 ttattaaata taattcttta tctaagactt caattaaaaa tctggataaa gttccattga
     1741 atgatttcat gacacctaaa ttcttgacat cctcattgtt tctagatgtc ttggctatag
     1801 catgtccctt tcctgatttt agggttgctg ttttagaccc aactctacag tatgaattta
     1861 ctccatcacc attttgcaca aaagtactgt attgattttc atcctctacc acaccaaatt
     1921 cgtctattag aatattctca tagagtattc ccactccctc tttgaaattt tctattatag
     1981 ccttatcagt tattccagaa gcaatagcta tcttttttgc gaattcatct attttatcaa
     2041 tattttcttc atattttttg tttatctcag gattattatg agcactgcct tcctcagcaa
     2101 gctcatatgt agcatcatat atccaatcat tgtatttttc tatttgtata ttataagtag
     2161 ttaacaaatc ttctaatttt gatacataat attttgctat ttctgagaaa tctcttgctt
     2221 tagcctctat attatctatg ctttttatac ctacagtatg tggtatagaa actattattt
     2281 gtttcaaact taagtctaga aataaagttg caaaataaaa agttttttct aatccagatt
     2341 ctatattccc attctcattt tcatttttac agctaattaa agctggagaa ataaatctta
     2401 taatcaatct tttgtttatg acatcatttt ttttatatat gaccttagtt tcttctaaat
     2461 cactagtatc aatctccaat aaattttcac ttactatatc ttctactatg ttttttaaat
     2521 cttccaattc caagtcagaa tcattgtaat taaaaacata ataattatta tgaccatcta
     2581 ttgtaaagat tgatatccat tccttaaaat aatctagttt ttctccatca ttttgtatta
     2641 tgtttatcaa gctatttata gcagtttctt tttttcgttt attaattccc caattttcaa
     2701 aatctttaag gtgtttcatt tgtaccattt gtaatatatt ctttatgttc tttagattct
     2761 tttcatttaa caaatttata atccccctct atttatatat ctttatgtaa tttatattat
     2821 catatttgta catcatttta gcaataaata ttattatcta cattaattat taaaaaaaga
     2881 cttagaattt aatctaagcc tttttttggg gatacatatt atatttaagg gagcaagttt
     2941 taggaatcga acctaagatt acacaccagt ccttgcaaat tgagtgaggt taccaagccc
     3001 cactctttta gacatttgaa ttaaattccg ttttaatcca gcatatctac atatagtgta
     3061 ttaataagtt tgaacatagt aagaattgaa cttacagcat cctcatgccc tgcctagttt
     3121 gttcatataa gctaggcgaa tcccttaacc tagcccacat atatttagtt ttgagagaga
     3181 aatattcatt tccacaatac tattatctca cattttaaat tgtaaaatcg gcagaaaagc
     3241 ggcaataaaa agacctagaa tttaatctag gtctttcatt atattattta attttccata
     3301 ttctctttcc attgcttcaa tagttactac ccaatcacga ccaaactttt tacaatcaat
     3361 attttcaact aatttgcctg tcgcaactgc ttttctaagt gtagaatctt tcaaatccca
     3421 taattttgtt gcttctgcaa agctataaat accttcaaat cgattcataa aatacctcct
     3481 aatcattgct agaaaattga gttaataaca taatataaca atattgatgc tccaattaat
     3541 ttaatagtgt catacagtag tttcaataat tcaaatgtta actctctata cttattcatt
     3601 gtatttttag tgactatgtt ttataattta gttaagaggg aaggtgcaac ttccactctt
     3661 aacattttac taatgtaggc tatctattac cattttgatg actgctaata gtgtgccaac
     3721 ttcgagtacg agttcagtta attcttttat gagttttctg aactctttta ttttcttagc
     3781 cactttcttt tcgcctcctt tctatacttc aataatatca cgtatgcgtg atattgtcaa
     3841 taacttccat atatcttttt cacaaaaaaa atagacagtt attaactgcc tataaatcta
     3901 acatcttaaa taatggttct tgctctatta atgctttttt accaaataag gctattgata
     3961 ttgaactaat ggcttgatta gctctttctc ttaattgtct ttcttctaag tatactttat
     4021 caactattaa actccattct aagccttcaa tatacctata ccttataatt tgtttatgta
     4081 taggttttaa attacttatg gatacatcta ttgtatattt tagtgcttcc atttcatata
     4141 attctatctg cttttctatt atcttttctt caagattaat taactcattt tcaacttgat
     4201 tacttattga attagtctta cttatgggaa tgctgtcata gcttaaacct tgcataaaat
     4261 cacctaaatg gaactctttg agatttttta tttgaagttt tagactttca atattaatat
     4321 gtagttgttt gtagttctca aggtgttttt tagttgccat aaaaaactcc tttttaactt
     4381 tacttgccat aacatcactc ctatttattt aagctacctt tttcttattt tcttttctct
     4441 ttttcttaag ttcactatat tctatccaac catctacccc atattttttg cttttagcaa
     4501 tccatatcaa ttttttgtcc tgatatttat agtcaaaaag cttttttcta agttcaccct
     4561 gctgtgtact ataccctttc acatctatat aaacgacttc accattccat ttgtatatgg
     4621 caaaatcaat tgtatatgta atagctctat agcttttccc atctttttta aatttaggtt
     4681 gtagttcaaa cttttgttga agtccaaagt cttttatttc tccattttcc tttttttctt
     4741 ttaaatataa ataatactct gactcatctt tactatcaaa tttaattcca tctattacaa
     4801 ttttcttatt attgtattta ctcaatcaaa tacttccttt atcacttaaa gttactcata
     4861 cttattaata tcgtttataa attcataaac ctcatgtaca ctatatccaa acttttcaaa
     4921 cccttttaca tatcttctta tggaacttga tatacttcta cctactatac aattctcata
     4981 tccttgcaac aagttttctt tttcctcttg cttcaccatt tgagaaactg ctttttgaaa
     5041 cttattcatt gctattcccc catagtttta ttgtttaaaa ttaattttgc tgttctctat
     5101 tgcttttctt agcctttctc tcacatcttt tacaacagta aattttttta gactgttttg
     5161 ggatgtaaaa taatttacca caccaattgc aaattattct tttattcata aaaccacttc
     5221 tttctcattt ttcaggatag ttgttattac aattttcaca ctcttttaga ttcaatctat
     5281 actcataaac tctaccagct ataaaactac ctactataag tattaaacta gccaagatgt
     5341 tcattttcta acatctcctt acgttctaag aactcttttt taatttcttc caaattctcg
     5401 cattcattac caactactac atattttttg ctattcatta tagttgcttt acttgtaatt
     5461 tcctcccatt taccttcaaa ttgctttaaa taatgccatt caacatataa ttcaagagca
     5521 taattttctt gtcttacaat tccatattca tatttatttt tagtattata gggttctttc
     5581 aatatatctc cctcataaat ttcttcatta tttccagacc aacatttaga gaatactcca
     5641 atattagata ctctttgcca ttcacaatct tcttttagca taaataaaca atctactgca
     5701 tcactccact ttattgtttc agaataaatc cacttctcat tctcaaaatc ataacctcta
     5761 tacttaatta aactcacttt taatcatctc ctcatattct tctctagcct tatctatagc
     5821 aataaatatg tcctctccat tgtcatacaa ctcttttgct cttttaattg tgtattcagt
     5881 ccttgaaact tccattattc ctccttaata tattcagctt tccagccact tcttgtttta
     5941 gttttctttt taattgtttg gtaaactgcc tgactctgta gtcttaaaaa acacgctgca
     6001 ctatctatag aatcaaatat tttttcttca ccagttttgg cattaatcaa ctttaccttt
     6061 gaacctttct ttttcttttt tctattttta tcaacattaa actctattaa cattttttca
     6121 catgttggaa atataagttc tccatttttt cttactccgt gaacacaaca atatagtgct
     6181 aagtaatttc tacatgtagg gtcatcatct atgatatttg ttcctaaaga accactaaaa
     6241 tatttttcaa cctttaacat ttcagtaacc tccctattta actggcattt gaaatattct
     6301 atttctataa cttctaacct tataactgtc tatagaatct gttctagttc caccttcaat
     6361 aaatctttgt atattatcca gcacttgtat agcccttttt tcatcctcat actcacctat
     6421 ctttttaaag ttatccatat ctccaaacat tgcatataca cattctttat caacatttat
     6481 ccaatcagct tttactaaat cagttttatc ttgacttcta attattatca tccctaatac
     6541 ccccatcatc acattttctt aataattctt ctaagcaact cttacatata acaattacaa
     6601 attctctacc atgcaaatcc ataacctttg tatttgtaaa ctggtcatca taactctcaa
     6661 ctagaaactc cccacaaaca ctacatatag ctgttctact catttttatc cctccatttt
     6721 taacttttag gaagtaatat tgtataatta ctccctagac tatttaactt aattaaaaag
     6781 gtatatcgtc atcatctatt gcttgaaaac cttgtgggtc taatcctggt ggtacatatt
     6841 cttgtttagc attattatca tttttactag aaagtagttc taaagcattt acattaacct
     6901 tagtaataga tttccagcaa ccattttcat ctttgtaatt atatatattt aactctccaa
     6961 cagcatatat aggcttacct ttaacaagat attgcactaa attctctaca tgttttccta
     7021 attgctcaca ttgaataaaa tcagttattt tatttccatt tttatcttta aaccttctat
     7081 ctactgccat tgaaaaggtt atttttggag tgcccgaatt tggaaggtac ttcaattctg
     7141 catctgcaac taatcttcca actaaagtta ttgtattcat ttaactagcc ccccttctat
     7201 ttttcttcct gctcttctgt atactcaaca aagtaagtat aagttgtctt gctattttgc
     7261 ttctctctag caatctttac tgtatatcca gctttcccaa gtaatcttaa taattccaat
     7321 ctatcttgtt cgtttaaaga accacttctt tgtgcatata ttctcgccat tttatacctc
     7381 ccctttctag gaagtaatat attgatattt acttcctaga agtataattt tatttaaatt
     7441 taaccttttg acttttctta attatgtcat ctagttcgtc aggtgaatat tgagtaaagg
     7501 tttcattgaa gttatgaaac ttatttttac tcacattagg agtattcaca tttttatgat
     7561 tagactgctt cttctcctgt ttattctttt tcttcctctc aaactcattt tgatactctg
     7621 taagttctaa attagttttt acacctgctt ctatccaatt atttaagatt gtttttacat
     7681 acttataatt cttaactcca ctgcctacag cttcatcaat agctcttatt attacatcag
     7741 cttccattcc atcatctaaa taagtcagta gttgaagaaa attatttgga gtaatcacac
     7801 ctatataaga ttcataatat ttttttatgc agacagtctt atttttttca gattgttcag
     7861 caataacagt agtaataaca tcattttctt ttaaacctat tttcttttta atactatttt
     7921 cttttatgtt gccgatttcc cgacctcggt tttgccggct tccggtttca ccgacttcgg
     7981 ttttaccagc ttccggtttt accggagtcg ggaaaacggc acacggttga gattcagtca
     8041 tttcaacact ttcagaattt acattttgag gtgtatcaaa aatatcatat ctataacctt
     8101 tcatttgacc tttttcatcc cttatttgtg tcctaataac aaaaccttcc tgcataagct
     8161 cctttaaagc attacttact tttgtcttac tatcttttct atagcttatt aatgattttg
     8221 catacacttt atggctaccc gacctttgaa atcttaacat ttgagtgact actcctacag
     8281 ctgaataaga aagattttca ttgtcgagga ttgtattagg tactcttgta aatgggtcgt
     8341 caaaatttat gtgaaagtat gtttcattat taaaattcaa tatatcacct actcttgatt
     8401 ttgcttttca taagcattac aaattgtgtc atattcttgt tttgttaaat cttttatctc
     8461 ttttccaaat ctcttaaata ctttctcttt taagctctcc ttattaacat ttgcattact
     8521 tgctattgca tataacctgc ttaattgttt atctgttaaa attctattgt tagaattact
     8581 tttagcttca tttttgccac tagttgcgtc aaaagtgtca ttctcagtta tgttgagtaa
     8641 ctgaat
//
LOCUS       DAGQVA010000117         8277 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.119, whole genome shotgun sequence.
ACCESSION   DAGQVA010000117 DAGQVA010000000
VERSION     DAGQVA010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.119"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(317..493)
                     /locus_tag="MIV85_003542"
     CDS             complement(317..493)
                     /locus_tag="MIV85_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962843.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(597..1205)
                     /locus_tag="MIV85_003543"
     CDS             complement(597..1205)
                     /locus_tag="MIV85_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2962844.1"
                     /translation="MGKFLRGKIMKSDSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            complement(1304..2128)
                     /locus_tag="MIV85_003544"
     CDS             complement(1304..2128)
                     /locus_tag="MIV85_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBY2962845.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(2306..3199)
                     /locus_tag="MIV85_003545"
     CDS             complement(2306..3199)
                     /locus_tag="MIV85_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBY2962846.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(3456..3893)
                     /locus_tag="MIV85_003546"
     CDS             complement(3456..3893)
                     /locus_tag="MIV85_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBY2962847.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(4150..4299)
                     /locus_tag="MIV85_003547"
     CDS             complement(4150..4299)
                     /locus_tag="MIV85_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBY2962848.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(4312..4542)
                     /locus_tag="MIV85_003548"
     CDS             complement(4312..4542)
                     /locus_tag="MIV85_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBY2962849.1"
                     /translation="MEIKKKLVMSFKNVKDKPVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(5233..5454)
                     /locus_tag="MIV85_003549"
     CDS             complement(5233..5454)
                     /locus_tag="MIV85_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBY2962850.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            6034..6291
                     /locus_tag="MIV85_003550"
     CDS             6034..6291
                     /locus_tag="MIV85_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBY2962851.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            6760..7998
                     /locus_tag="MIV85_003551"
     CDS             6760..7998
                     /locus_tag="MIV85_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBY2962852.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         3160 a          953 c         1071 g         3093 t
ORIGIN      
        1 gactttacaa tataatagaa atgttgcaat aacaaaatac cataataaat aagagtttgc
       61 aatataatag aaatactgta ataacaaaac actgcaataa ataagagatt gtaatataac
      121 aaaatcctat aataaataag attttacaat ataataaaaa tcctataata aataggactc
      181 tgtaatataa taaaatgctg taacaacaaa acactataat aaataagacc ctgtaatata
      241 ataaaaatac tataatatag taaaaatcat gcaataataa aaatctataa taataaaccc
      301 cagcataaca aagacattaa tttcttacta aaaaggccac cacaattaac agtgaaaaag
      361 caattgaaag tattgaaaaa gtaaagtgag aattagagtc attattacga ttattaagtt
      421 ttatccataa accacatata attgtacaca acaataaaat tgctgatatt actcctataa
      481 atgtaaaaaa cattaaaatt cctccccctt atttaatgca agtattttta gtcaatgaga
      541 atattttcaa acgttaccat aaaataaaaa aatgtacata aaaaattaat atagtattat
      601 tttgtaatat ctaccaataa taaatctaat tgaaaatcta ttaaaccatt tctctgttca
      661 acattaagaa tatcaatacc actatacttg aaaaaagcat tagaacgaag aaaaagcaac
      721 tgaataaatg aagttatttg atacgcaata gttctgtatt cagcttcagt ttttttgtta
      781 ttctgatttt catagtgagc cttaattaaa ggtagtatct caaatggata aacaatttct
      841 tcctgtatca atatataggg tacagaaatc tttataaatt gactatgttc acctataaaa
      901 tcaaaaaatg caattagtat ttcccttaat tgctgtttag gtgctaaatt tttagtatca
      961 tgtgtagcct tatattcatc catatgacgc tttaaaaatt ttttaataga aatattaatt
     1021 aactcctctt tagatttaaa ataataatta atcatagcta aattgacatt tgctttagct
     1081 acaatttctc tagccgtaat gcttgaaaca tctctatgtg aagatagtaa ctggattgta
     1141 gcattaatta attgttcctt tgttgaatct gatttcataa tttttcccct taaaaatttc
     1201 cccataaaaa aattaaacat gtttaataca cgtttagata ctatcatgaa aattttggga
     1261 tgtcaatggg tgattagtac ttaagtattt aagtactaat cgattagact tttataaggg
     1321 ggatttgaat ttctgtaaga taattttcag gatttatttc attatgttca cctttatgac
     1381 cgatttgtct atttatacct gatatttgat aatcactatt tttatctaac caataacaga
     1441 acgattcata tgcaccagct atattttcat atggaccata aaccatagta catgccatca
     1501 tatcaatttc ttctgtctca cgatatataa atccagattt gttctttcca atcttcttta
     1561 caaccattcc aacttcaata tctacaccat tatctttgac ttcttcatca tggtaaaaag
     1621 ctatgttatt gttggattga cgtgatactt ctatatgttc ttctttgata aatttagata
     1681 gcttttccca gagtatacct tcagattggt agtctggaat tatctctcta agtgatatga
     1741 ttttataact tggaatcttt ttaaagacaa cattgtaatg aatttcatct ttatcacagt
     1801 ttatagcttc tataaattta tcaattttat ttattctttg ttgttcctgc tttatttcct
     1861 tttgtatttc attctttttt ctattcaatt ccttaattac aaattcatca ttccaattat
     1921 gtacgatatt tgctatttct gcaacgctaa attttgaatc tctcaataat acaattcttt
     1981 gtaatattga aatctgttca actgagtata atctatgacc tgtatatttg tctatttctg
     2041 caggctttaa aataccaagt tcatcataat aacgcaacat acgaatagaa atttgtgtta
     2101 gttttgaaac ctctcctatt ttaaacatga aaatatgacc tccttttcac ttataatcag
     2161 tatatatttt gtttttatat acttcaagcg tttgtggaaa tacaattatt ttccagatgt
     2221 tgcaataaat tatagagagt aaattatatt taagtagtaa tcgtatcaaa tcatagatta
     2281 tattaattta taattcatat taaaattacc agtctaactc aaattcaaaa tcatccgact
     2341 ttatctgttc aatttcagaa tttaccttct gtttaaattt attagaagaa atcatatata
     2401 caagaaatat taaaccaaat attatttgta catattgagc tattacacat aatttaatag
     2461 ggtagtgtag aagtaattga atgttgaaaa aatagtacat catatgaact aatccagctg
     2521 ataaaatgct tctacttgta ttgatatata caaaattaat tataaagttt aaaagtacaa
     2581 tgtttggtat aaataaaaaa gcatcaaata gggagtattg tgccaaatta tatggtattt
     2641 gattaggtgt aaaatacgac cctagatacc agattccaca aacaagccct aaaataattg
     2701 aagaacctat aaatccaaat ctaactaata atttgtcaat ggcgtatcct ctccatccag
     2761 cttcttgact aagtatactc aatataaaac ttgctaatag catataagct attttagaag
     2821 gtctaaacac tgctatatgt atccaatcta tatcagaagt ttttacatta aagtaatttc
     2881 cgattattaa cgaagtaata aaagttaaag caaaaaataa tattgttaat agtatccatt
     2941 ttattccgat ttctttaaag cttaggtatc tataaataaa atcttgtttt gcactttgtg
     3001 gatagattgt agaaataaaa aatagaccta caatagctgg tgatgtatat gcaagataaa
     3061 aaatgatttc tccaagtatt gtatttgtaa ttccgagtaa cgcaggtgta agactgaata
     3121 tccagttcaa tactagcgta aatgtaaaga aatagattaa gtgtttgttt gtattaaagg
     3181 gggtgttata tagttgcatt ttttcactat ccttccgttt tataatgaag ttttaatttt
     3241 tattaattgt ttatttattt ttatatgtat taagttatcg cttgatgtta gttattgcct
     3301 ataataatat cctatttttt atattttgat taattatttt tacactaaat ataattaatt
     3361 agtatttaat attgaatata ttatattatt attaattatt aaataggtca ataaatttgc
     3421 aattagtgat attaataaat tactttagat ttttattaaa tgtttagctt ttctttaata
     3481 ttttttatat aacgacgatt tataataact ttttcgttgt tttttaaagt agcttgcatg
     3541 cgattatgtg atattacttt tatacttttt atgtagtcca tatttaaaat catggattta
     3601 gatattcgtg agaaggatgt attagctaat aattttgata atttatatat ttttaaatca
     3661 atttcaaata catcatcttc ataataagca aatgttttat ttccaactgt ctcaaagtat
     3721 aaaatatcac agacattgag tttataaatc tctcctgatt ttttaccttt tatatcaagt
     3781 aacggtgtac tcaataatga aattattttt tcaatgttat tatctagagc agaacatttt
     3841 atggttattt caatatcatc acaattaata ccttgttcga catgtatttt cattaatcat
     3901 cacctcattt tattactgtc attagaatag cattatatct tattgagtcc aactagatgc
     3961 gttctaaatt tcaaattaag catagtgaaa ttcaaaaata aaacagtgaa attcaaattt
     4021 gaggtggtaa aattcaaaaa aatactatgg atatttggat aaattatcca aatatcctag
     4081 tatttcacat agaatatgtc taattatttt acaaatagac ctattttatg acttacatat
     4141 attgtcaaat tacttcttaa atatcaaaat atttttggat aatgtatcaa tactgtttga
     4201 taaagtattt aatttaccct caattctaac caataagtac atggatagag ctataggaaa
     4261 accaacattg gttattaaca gttgtaaact atcatccata aaattagccc cctattctat
     4321 aactaagtca taaggagtgg tatttgtttc cacaaccttg gcttcaacaa cagaagctag
     4381 gtcaaatcct ccaaccgaaa aaatattttt agatactatc aaatccatga cagattttat
     4441 attttcttca gttaaatcat cctttggatt ttctatagaa aaagaaactg gtttatcctt
     4501 tacattttta aagctcatga ctaatttttt cttaatttcc atataattac ctccgatata
     4561 ataatttata ttttaattgt ttgcttgtta atattggtat tttaattgtc aatattagtg
     4621 ttttgcttgt tagtattaat atttcaattg tcaatattaa tgttttgctt gttagtatta
     4681 atatttcaat tgtcaatatt agtgttttgt ttgttagtat taatatttca attgtcaata
     4741 ttagtgtctt gcttgttagt attaatattt caattgtcaa tattagtgtt ttgcttgtta
     4801 gtattagtat ttcaattgtc aatattaatg ttttgcttgt tagtattagt atttcaattg
     4861 tcaatattag tgttttgctt gttagtatta gtatttcaat tgtcaatatt agtgttttgc
     4921 ttgttagtat cagtgtttca attgtcaata ttagtatttt aattgttgac tctagttatt
     4981 gctgatatag aaaatattta atttatttca attaattaga ttaaagtagg gtagcatcta
     5041 aaatagctaa catgtttaag ttgaaatacg tttaatatat taatttttca aagcattaat
     5101 atattaaagt tataaccaaa attgaagtta taatctgcca aatctatagc gtattaagta
     5161 cgttatataa cttaatcttt tatataaaga gttaattttt taatttgtaa agcagagtac
     5221 gtttaaaaga tactatttag ataatgatgt actatctaat tttaaaatat ctacaatagg
     5281 gttctcttga agacttgcta ttgcttctgc aacagcataa acatcttcat ttaatgcctc
     5341 tgcttttaca tttgcaaatg atttactttt aacaactgcc ttacccttat catcaaaacc
     5401 agcatccaat tttagtttta tactagataa attttttgtt gaaacaactt ccataaaatt
     5461 acctcctaaa aatttaattt caaagatttg tcgactttct ttgttagcta taatactatc
     5521 atctaagata atatcggagt taaacagtaa tttctaaaga ttttttgtgt aaatttttat
     5581 aggaaaaatt ttactttttt gctgatgaaa aagtttacaa gttatttgtg aagatatgtt
     5641 cttagtgttt tgaaatagta tttgtatata ttcctgctta gttgagatag ttttgtatgg
     5701 attttcatat gtgtagagtt aaatgttagg tactaaagtt tatgttaaat taaatgttaa
     5761 agcttatgtt aaaaatttta ttaaatttaa tctgtaaata aaaaagttaa aagtccaata
     5821 ttaacatttt acttttaaac cattaaaatc tttattaaag ctaacaaagt tataagttat
     5881 gagaaatttt attaaagtta atacaaaaat taattttaaa gctaagaaat tttttattag
     5941 attcaataaa actaataaat atagtttagt caataatgta ttaaataaaa actttgttaa
     6001 gtctataaaa atatcttaaa ggaggtgtaa cttatgaaga taaaagtgga ggatatacca
     6061 gttcaatttc atgcaatggt agaaataatt ggaattgata agtttataga ggttgccaag
     6121 ttgtatggag gaacaaatac ttatatacct acgtataagg ggctttttag atatgctaga
     6181 aatagggata tagtaaaaca atttaatgga gtcaaccaca atgaattggc tattagatat
     6241 aatatgtgtg taagcaatat taagcgaata ctcaatgaaa ataatgttta aatataataa
     6301 aataatgttt aaacataatg aaaatagcct tgttaaacgt aagagtaaag acaaagaaga
     6361 tgttttataa agttttttta gacaaattaa ctaaatttac tacttattaa tttaaataca
     6421 ttgtatattc tataaaaaaa tttgttaaat actggagata tattgagaat acaaagaaaa
     6481 tggtcgaaaa tatttgttgg ctaaaaaata gataaaatga tacaattgct tgtataaagg
     6541 ggaaaaataa ataaataaac tatataaata aagaaatagc aattaatatg acataatata
     6601 tttataaaat taagaatata aatagatatt ttaaggtatt agttgttaaa ttaggaaata
     6661 ttaaaaaaaa tatatattta tatttaaact attttgttat ttatataaaa atacttatct
     6721 agttactagc aattattagt agaaatgggg gaaatagaga tgaataaggg attttacaaa
     6781 ttaaattcag tggtattgaa ctttgatatt aagaatgatg ttaacaagat aagatttaat
     6841 cattatataa tgagaaaaga aaacatacaa agacttcaag gaactctgcc aaacggacaa
     6901 ttttatatga cagtgagaag agctgctaca gatttacaac tttctatttc tactataagt
     6961 aggcttgtaa aagagttttt ggatttaggg ataataagat tagtgtctaa gggtgtaaaa
     7021 ggtaatcgtt ctgtatatag ttacgtaagt atagagttta atggaagttt atttgatgat
     7081 agcaaatata tggaacttga ctgtgtatgt aatgatgaat ttattgataa tagtggcata
     7141 gagtttgatt gtgatagcaa agataattct tttaatggag atataaatgt agaaactgtg
     7201 cattgcatta atgagtattt gtctgatgat gatgtagagc ataattataa caatttccat
     7261 aataaagata ctataaagga taaagccatt tctaatatta gcactatcaa aaaatatatt
     7321 gatgaatctt ttgataaaaa taaatcagaa aattctaact tacaacagga gtcaataaat
     7381 ttcaacttta atgatacatg caatgaaata gataaaagaa cgaataatag tatagaaaat
     7441 aatcaaaata aaaggcctat gagattgagt gacatcagtc ttttaagtga taaaggtatg
     7501 acaaataaaa agaattactt taatcataat catggtatac aaaaagggac taaatctgta
     7561 acaaagaaaa aagaatcctt aaataaattt aataaaaaaa atatacagca aagcattata
     7621 aatatgctaa ataaaaaatc aggtaagaat tttaaaatcg attctccaat aagcataaaa
     7681 cttatcaatg aaaggctaaa ggaaggctat gtcttagaag atttctacaa agttattgag
     7741 gtaaaagtgg ctaagtggaa aaataccata atggaaatgt atataagacc agaaactttg
     7801 tttagctata agtttgaatc ctatgtaaat gaaaacatat ctatgaaaag tcaaagtaat
     7861 gttcacccat gtaaagaagg caatagtaat gatagcagta attatataca ttctgattat
     7921 acaacatatg atggcagtgt gcgtgagaga aaaaaatatg agaatgtaag atactggaat
     7981 cctatatgtg aaatttaatt agtttaagaa tgtatttatg ataaataaga tattaataga
     8041 gaatagtgag ctatagcaaa tgatatatca atagttggta gtaagttata ttaagcaaga
     8101 tattactatc aggtagtgaa ttatattgaa cgatatatca ataattggta gtaaattata
     8161 ttaagtaaga tattactatc aggtagtgaa ttatattgaa cgatatatta ataattggca
     8221 gtaaattata ttaaataaga tattaatatc gagtaatgaa ttatattgaa cgatata
//
LOCUS       DAGQVA010000118         7980 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.121, whole genome shotgun sequence.
ACCESSION   DAGQVA010000118 DAGQVA010000000
VERSION     DAGQVA010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7980
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.121"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            281..2515
                     /locus_tag="MIV85_003552"
     CDS             281..2515
                     /locus_tag="MIV85_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBY2962853.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2546..3379
                     /locus_tag="MIV85_003553"
     CDS             2546..3379
                     /locus_tag="MIV85_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBY2962854.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKKKFDKND
                     Y"
     gene            3619..5352
                     /locus_tag="MIV85_003554"
     CDS             3619..5352
                     /locus_tag="MIV85_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBY2962855.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENTQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDNTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5744..6236
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5813..5841
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(6766..6870)
                     /locus_tag="MIV85_003555"
     CDS             complement(6766..6870)
                     /locus_tag="MIV85_003555"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBY2962856.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7495..7740
                     /locus_tag="MIV85_003556"
     CDS             7495..7740
                     /locus_tag="MIV85_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962857.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
BASE COUNT         3201 a          948 c         1052 g         2779 t
ORIGIN      
        1 gctcacaatc tatctattta tgaaaaaata tgatataatt gcattcaaaa aggaaatctt
       61 tcaatatact agaatttaag cattaactaa ttttatctaa tattattact aaactaaaaa
      121 atatttgtat ttgtagcatt ggagcaagta acttaatgta tattcatttt aaatacttat
      181 ttaaaattta gcatttaaat tatttacaaa ttaacattta aatacttcta gcataaatac
      241 agttgtcatt aaaatttaaa gtatcttatg gaggaatacc atgcaaaatc ataattatat
      301 aaaaatgtta aataaaaagg tagaagtatt atctaaggaa ttagatagta gaaattttaa
      361 attaaaaacc ttaaatgaaa tagatttttt ttctaaaata ccaaacagag aatttatgta
      421 ccaacatatt gatgactgta tttcgaaaaa tatacatata ggaatcatgt tattaaatat
      481 cgataacttt aaattattta atgatatata tggataccta gtcggagaaa atttattaat
      541 tactctaact caaaacctat tgcactttat tccagaatca aagggaatag tcgcttattt
      601 aaaaggagaa ggttttttaa ttgtacttcc aaatgtatca aataaagagt taaataatat
      661 gggtgcaact attatagaga gcgcccgaga attaaaaata aaacttccta atgaaaaaga
      721 aatatactcc aatgttacat ttagtatcgg cagcactatc tggaatggtg aaccaaacat
      781 gactactttg atgcttttca accaagtata tagtgcttta aaaaaggcta aaagtgaagg
      841 taaaaataga tacattctat ttgattttaa agataatagt ttttacaata aattagaaaa
      901 tgataaggag ttcttatcag aaatatcaca tgttctacaa actaaacaaa ttgaagtatt
      961 ttaccaacca ctttataata taaaaaataa tactatagtt ggatgtgagg cacttgcaag
     1021 atggagacac cctattaaag gacttcttac tccagataaa tttattcctt tatttgaaca
     1081 gtttggtctg ataacggaat tagatttgca tttatttgaa gagaactgta aaaatataag
     1141 aagatggatt gataacaatg atgtttttgt tccaatttgt tgtaactttt ctcgtcttca
     1201 tttttttaac cctaattttc caagtatgct aaaaggtatt actgaaaagt acagcgtctc
     1261 tacatcaaat tttagcattg aaataacaga aaatatatta atagaaaata caaatacaat
     1321 tattcaacaa ctagctgaac ttcgttctta tggtttttct gtatcaatgg acgattttgg
     1381 ttctggatat tcatcttttg gtatgttgca aaatctacct tttgatataa tcaaaattga
     1441 taggatattt ttatctcata atttaaatga ttttaaaaat acaaccattt tgtactctat
     1501 aataaacatt gcaagagctc ttgggatgct tacagtatgt gaaggtgttg aaacagaaca
     1561 acatgtagaa tttattaaaa gtataaattg tgatatcgcc caaggttatt attatgcaaa
     1621 acccatggag tgcaaagaat ttgaaaaatt actatctaaa gagaataatt cagagaaaat
     1681 gtttataaaa tattctgata taggaaaatc tttaatagag aagatatttg atggattttt
     1741 tattatgcaa gatatgaaaa aactaagagc taatgtcact gaagacattc aatggtttga
     1801 tttttacaac aaaactgaaa ttacatcttt tcctaaagta atagagcatt ttgaaaaaca
     1861 tattaaaggt aaaaaatttt ctattcttta caaaagtata accccacata atactgaatc
     1921 agattcatta ttaattagtg gagaagccgt tttatcagat gaagcttctg aacatcaaaa
     1981 atatagcaat ttctacttta gtgcaaattg tataatttca gaaaataaat tactcttagc
     2041 aaaattacat ttggatttaa ttaaaactgc tggctatata aatgaatttg aatcatattc
     2101 aatacctaaa atgacaaata cacatcttga tgaaagtaat attttatcac aattttattc
     2161 aatgttgcct gtaggtataa ttcgctacga tttatttggt gatatgatta ttacttatat
     2221 gaatgaagaa atgtttgata ttataggtta tacaaaagaa cagttttttg gtgagatggg
     2281 cggaaattta agagcaattg ttcatccaga tgatttagac tttgtttata aaaaaagttt
     2341 ggatatgatt gacacaaata aaattgaacc atttttatat agattcataa aacgagatgg
     2401 tcaaattgtc acagttatgt atacacaatg taacctttct gcaattgatg gaaggtcgat
     2461 tgcccagggt atgtatgtag atgtaaataa aataaaaaat ttaacaaaaa tctagtacaa
     2521 agtattttat tttggagaaa ttaatatgtt taaagaaatt tttttaagaa cttttccagg
     2581 atttctaatt ataagagatt ctaactacag aattatattt ataaatgata atttaaaaaa
     2641 tttaattaaa agttatatgc aagataatcc acttggaatg actaatatag aaatagctaa
     2701 gaaactccct gataatattg ctaaattttt tacggattct cacaatattc aattagattg
     2761 ggaaaaaaat tatccttatg ataaaatttc aaattggatt ttagagttta aaaaagatac
     2821 tacaagctat tggaatgttt tagaatataa agtagatgtt gatgaaaaaa cctacataat
     2881 tactatggcc aatgatataa caaaactcta tgaagaaaat aagagaaatc ttcactactc
     2941 aattactgac ccattaactg gagcatataa tagaaaatat ttaaatgata gatttgacat
     3001 atttatagga gattatattg tactaattga cttagataat ttcaaaatga taaatgacta
     3061 tgaaggtcat aatgtaggag acaagatttt atgtgatttt gtttcacttt taaataaaga
     3121 attaataaat tctacttcta ttataagatt aggaggagat gaatttattg ttatattctc
     3181 tagtgatgtt gacaaaaatt atgtttattc acaactagaa gccttaagag aaaatttttt
     3241 aaaagtattc tctaagtata agtatctttc atttagttat ggtgttgata cagtaaaaag
     3301 aaatttaaaa ttgacaatag ttgaattgga taaaaaaatg tataaaaaca agaaaaaatt
     3361 tgataaaaat gattattaat attgttattt taaaataaat taaaattatc tttctttttt
     3421 taaacttgta cattagttta taaatatgta tctatacaag atattgacat taagtactga
     3481 agcatatatt gtttcagttc ttttttgtta aaattaactt atttaacaaa gatatcatag
     3541 tttaacaaag cttttaattt aaatatattg atgtataata taattaaaat ataatagcaa
     3601 aaagaaagga ggaatatcat gagcatactc ctaaaaaaag cacccaaatt agcaaaacat
     3661 attataacaa gtttttatat aaatcgggat attgatgaag tattaaaata cctttgtgaa
     3721 aatgttacat ggatcggacc aggagaacag gaatttctca cttcttttaa tgaaataaaa
     3781 aattattttt atgcaggtca agatgaaatt ccttcttgtg atataaataa tgatatattt
     3841 gaaactgtaa gtgaagatga gaatagatgt atggtattag gaagatatac tgttcgaact
     3901 aaagaaaata ctcaaatgat tttagaggta aatcaacgtt gtacatttga gataattgag
     3961 gatagaggaa aattattagt aaagcacatg cacatatcaa acccttatgg tgaaatgcaa
     4021 cttgatgaat actttcccac taaaattgga actcaaagtt atgattattt gcaaagatta
     4081 ctaaaggaaa aaacagaagt tattgaaatg attacaaata atatcaatgg tggcttaaaa
     4141 ggtagcaatg atgataatac atactcattt ttctatgtca atgaaggatt gcccaaaata
     4201 ttaggataca catatgatga gttcatggaa atgagtggtg gttcagcagt gggtgctgta
     4261 tatccaccag acttacctaa agcactagaa gattgtgaac gatgttttgc aaaaggacct
     4321 acatattcat ctgaatatag aatccgaaaa aaagatggaa cattaatgtg ggtattagat
     4381 tctggaatga aatcattaaa tagtgatggc atagtaaaaa ttaatagtat tattactgac
     4441 ataacccaac taaaaaacat agaatctgaa ctaaaattag aaagagagcg atatcgtatt
     4501 gctttgcaaa atattacaga tatcatgttt gagtatgata ttgaaaacga tacccttata
     4561 aaatatcaac gtgtagaaat tgacaaaaaa attgaattag aaaattttga aacaaaaaat
     4621 tactccaaac tattagaatc tggtaaaatt attcaccttg atgatattgg aaaactacta
     4681 gaagtacttc atggaaatct tcgtgaaaca attgagataa gacaagtaaa ttcattaact
     4741 aaaaatgaat ggagatggat tcgtgttcaa tgttcagtta tatatgatag tgaccataac
     4801 cctatcaaaa caataggcgt tttaaaagac ataactgaag ataaatctaa attagaaagc
     4861 ttaattaatc aggctcaacg tgacccacta acacaattat ataatcaaag agtatcacaa
     4921 aatcttattg aagagtatct atgtagttct gattccaaaa ataatgatgc tctattagtt
     4981 attgatattg atgattttaa aactgtaaat gatacttttg ggcatttaga gggaaatgaa
     5041 gttttagttg ctgtatcaaa aatactatta cataacacac atgataaaga catagttgct
     5101 cgaattggtg gagatgaatt tacaatattt ataaaatcat taacaaagga tttaataata
     5161 aaaattacta atgatatttt aaatgatgca agtaaaataa aagtaaagga caatcataaa
     5221 ataacattaa gtattggtat tgccttcact gatgattcaa ctaaattata taaagattta
     5281 ttttctaaag ctgataaagc tctttatcta tcaaaagcag atggcaaaaa ttgttatagt
     5341 acatacgaat aataaagcta tttatacgac caagaatgaa cctttaaatt taatttcata
     5401 gtctaacaat caaagagttg aagctaatct tatagctagt caactagttc ctagaaaaaa
     5461 tttaaacaat atatttattg atactgctca tttttctaaa gagcaaattt atataaaaaa
     5521 ttaaactttt atgtacatac agatactaat gataaacagt tatcattagt atcttctatc
     5581 ttaaaacaaa atgataattt atctatataa aaaagtgctt tgttgacaga gttcactttt
     5641 ttatataggt acagaattta agtataaata catgttttat tctatacatt ttagttaatg
     5701 taaaatttct tgattgtact ctctaacttt tcaacattat actatttata taccacttag
     5761 ttaatataaa ccccttagct ggttctagtg ctttttctat gattttagtc atatttacat
     5821 accacttagt taatataaaa ccaatttaga tgatgtatat gtgcaaaagg aagaaataat
     5881 ttacatacca cttagttaat ataaaacgct actaaacttg atatacatga ccattataat
     5941 aataaattta cataccactt agttaatata aaacttccat aaaaacatcc cctttttatt
     6001 cttcttcctt atatttacat accacttagt taatataaaa cagtcttttt ttaatgcaga
     6061 gatgcaagaa gttttataat ttacatacca cttacttaat ataaaactat cagtatttaa
     6121 gtaataattt aagtaatata ggatttacat accacttagt taatataaaa catattttgg
     6181 atttattaat ataaacataa ttaaaaaatt tacataccac ttagttaata taaaacccca
     6241 aaataaactg ggcattttca atacttacac atatgcaact ctcttaaatt tgcagtgaac
     6301 catgagtagt gcaaatgata aagcttatca tataccctca acaccttata tttcaagcgt
     6361 taagctctac tttgtaacaa atatcgctca ctgcaaaact atttacattt ttattatatc
     6421 ataaatatat tatttttgaa tatctatacc aatttgtggt ataataaaag caagaagaac
     6481 tacaatctat ttagacgtag agtgaagttc aaatactaat gtttattctt tttgaacttg
     6541 atttttagtt caaaactaaa gtcactcctg cctgtgtgaa ctatacccgc tgttttatac
     6601 agttaaaaca tgtaaaaata gttataaagt actagtgtaa ctcattagta ctctttttat
     6661 tatattcata taattaatat ctatatttta aagtttacta tctaaaaaag agcacgtcaa
     6721 ataaaaccct agatatttaa tttttttaga gatacttaaa ataaattatg ctctctctgt
     6781 acttaaatat ttcctaaatt caaatggaga catagaattt aatctatttt gatatctaaa
     6841 attattatag tagtatatat aatcatctat tgctttaact aattattcat atgtatcaaa
     6901 tttccttaaa tagtacattt ctacctttaa aattccccaa aatccttcca taggagcatt
     6961 gtcaaggcaa cgaccaactc ttgtataata tatgtatatc taacaccatt aagaaatata
     7021 tattttataa tatatatttc ttcatttaat gcacttagaa aagcaaagaa aatacagatt
     7081 agtacacttt ttagagaaaa ataaaattaa tacatctaaa atattaaaaa atactttaga
     7141 taatctaaag acacatctca aagtttttaa ctaaattata aaactaatta caaatgctat
     7201 gtaacgataa taaataaaaa atttacttcg cttaagcgac gtgtcgttga aatatttcat
     7261 gttgccaact ggttcgtaag ttgataagaa aagaacacta attatttaga gttcttttct
     7321 tagctacaag tggattataa tacttttaaa tctgtgagaa aatcatatat aataatgata
     7381 tgaacaagta aagaaaatac aaaaatgaca aaattataaa taaaatatta taaaatcata
     7441 aggtcataat tgttatattg tagaaacaaa gtaaagagag agggtggaga ataaatgaat
     7501 caaaaaaaaa taaagattag tattaaaatg gtaattatag gtatatttgc tgtaattatt
     7561 gcttttgtat tatccagatt attcgttgag tatattgatg aattattaag gtctaattgg
     7621 caatatcagc tatttgaaag tgagagttca tatatagtat ttgccaattg tattatgttc
     7681 tcgaatatat tattagaaat atttttaata tatatttgta gaaaatttag aaaaatctaa
     7741 tatggtcaac gtatttcgaa tcgaatactt catgattatt tagtctattg tgctagttaa
     7801 agtttaattc ccatataaag taaattgatt ttagtaaaac aaatcacccc taagggttag
     7861 tttatggata agtcatccaa atattaactc tttaattttt gctatagatt catctttgct
     7921 cataacttta cttataaaaa atgaaatatt ataagctaga acttttattc taattctagt
//
LOCUS       DAGQVA010000119         7717 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.122, whole genome shotgun sequence.
ACCESSION   DAGQVA010000119 DAGQVA010000000
VERSION     DAGQVA010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7717
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.122"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            220..1521
                     /locus_tag="MIV85_003557"
     CDS             220..1521
                     /locus_tag="MIV85_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2962858.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1597..1872
                     /locus_tag="MIV85_003558"
     CDS             1597..1872
                     /locus_tag="MIV85_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBY2962859.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3315..3545
                     /locus_tag="MIV85_003559"
     CDS             3315..3545
                     /locus_tag="MIV85_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2962860.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3538..4119
                     /locus_tag="MIV85_003560"
     CDS             3538..4119
                     /locus_tag="MIV85_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBY2962861.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSI"
     gene            complement(4694..5371)
                     /locus_tag="MIV85_003561"
     CDS             complement(4694..5371)
                     /locus_tag="MIV85_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBY2962862.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5560..6924)
                     /locus_tag="MIV85_003562"
     CDS             complement(5560..6924)
                     /locus_tag="MIV85_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBY2962863.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTIFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7052..7573
                     /locus_tag="MIV85_003563"
     CDS             7052..7573
                     /locus_tag="MIV85_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBY2962864.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3009 a          871 c         1335 g         2502 t
ORIGIN      
        1 aattggtagt aaagtatatc aaataagata ttgctattat gtagtaaatt atataaaaca
       61 atgtatcaga ataaatagta tattaataat ttgtagtata tcatgacgaa taatacagtc
      121 ataacaaata gtgagtcata acaaataatg tatttataat tgataatgta tttaaaaatc
      181 aaaatataaa aacttataag gaaagagaga ttaatttata tgggtaaatc aaaagatgtt
      241 gaaatagaga agtctatttt aggcacaatt cttttagaca ataaattaag ctataagcta
      301 gatgaattaa atgaaaacat gtttatgaat gatatatgtc ttgagatatt taaaattatg
      361 aaagaactta aaaaagaaaa catagtgatt gatgtggcca ctgtgaaatc aaagatagat
      421 agaaaatctc tagcaataaa aacgagtgat gtgactaatc taattacttg gggtcagaat
      481 tttggtcttg atggtcatat taaaatttta aaagaaaatt tagctagaag aagcataaat
      541 caaaattgcc aaaacctttt acacagccta aaccttggag aaaatatcga tacttgtatt
      601 tacaaatttg aaagtaatat aaaggagatt ttggacaagg atacttatga aaatgatgat
      661 gtaaatagta tagcagggaa ggtgcttgat tttttagaaa acaaaaaaga tattggattt
      721 aaatttggta taaaattact tgataccact ataggaggtc tttttaaagg agagctaacc
      781 acaatagcag ctaaatcggg ggttgggaag actgctttgg cacttcaaat aatgttaaat
      841 tcatttaagc aaggtaaaaa aactttattt ataagtagag aaatgaccag tgagcaagta
      901 tttatgagaa atatatgcag agtaactggt gtaagtacaa ggaatatgaa atctaaagaa
      961 atagatgaaa atgattggaa acttattgta aatgctatag gtgatttaag cgaaaataac
     1021 ttaatttata tcaatgataa gatagataca attagtgcaa ttagaaagag gataaggcag
     1081 gtaaagccag atttattaat agtggattat gtgcaactcc ttacatctca gaaaagcatg
     1141 gataagagag aaagggaggt agctactttt tcgagagaac ttaaaaatat gactttagat
     1201 tttaatatac ctgtaatcca attaagtcag ttaaatgatg aaatgaaaga ttcaagacct
     1261 tatggagata gacctatgag ggatagcaaa gccatctacc acgatagcaa caatgtggtt
     1321 tatatacatc aattaaaggg gagtgattat gaagaagcag tgagagatat tggagaaagt
     1381 gaggaggcag ttagagcatc agaatacagg ggaattaaga tggttgattt aatagttgcg
     1441 aagtgtagag atggacagac taggcataag catttttgtt actttgggga taagttacat
     1501 tttcaagaac taaattatta ggtcaataaa gtagtaataa caagcttatt aaaagtcggg
     1561 aaatagcaaa tagattataa aatatgaggt gaaaatatgt tggaattaag aaaaattata
     1621 gaattacttg aagaacacaa gatagaagta agtattccaa aggagttaca taagtatagt
     1681 ttattggaat accttgaatt gtgtcaacaa agtgggggaa catattttta tattaaaaca
     1741 ctggaagggg ctttaaaaga ggctagaaat gagcttatga ttaaattgtt taatgggaaa
     1801 aattatatgg aattagcgag gatgtttgaa atgagtgtta ttaatgtcag gcatattgtt
     1861 agaaaaaaat agatattttt ggagaataca agtgtgatat acttctgaaa tagaagttat
     1921 tatagttgaa ataaaattgt ggttaataaa ttaaagttgt gtataagttt aagattatag
     1981 aggagtataa gtgtgattaa caacatgatt ttgtgaataa aattgaggat atatatgatt
     2041 taaatgtgtg attaataagg taaggttgtg tataagatta tgagtattta aaaggagggg
     2101 ctataattaa tagtgtagag ttgtgtgttt gcttaagatt atataataat ttaatagatt
     2161 aaactatact aataaggtaa aatcgtgtgt ttagttaaag cttattataa aatcttgata
     2221 tgtgattaat gatgcaatat gtgaataaag ttaagattat aatagattta acctgtggct
     2281 aatagaataa aattgtgaat aaagttaaga ttataatagg tttaacctgt gattaataga
     2341 gtaagagtgt aaatagagat aaacttcaat atgagcttaa cctatgatta atagagtaag
     2401 agtgtaaata gagataaact tcaatatgag cttaacctat gattaatata gtaagagtgt
     2461 aaatagagat aaacttcaat atgggtttaa cttgtgatta atagagtagg gtgtaactaa
     2521 agataaactt caatatgagt ttaacttgtg attaatagag taaggtgcaa ctaaagataa
     2581 acttcaatat gagcttaacc tatgattaat agagtaagaa tgtaaataga gataaacttc
     2641 aatatgggct taacttgtgg ttaatagagt aagagtgtaa ctaaagataa acttcaatat
     2701 gggtttaact tgtggttaat agagtaagaa tgtaaataga gataaacttc aatatgagct
     2761 taacttgtga ttaatagagt aagagtgtaa atagagataa acttcaatat gggattaact
     2821 tgtgattaat agagtaagag tgtaactaaa gataaacttc aatatgagct taacctatga
     2881 ttaatagagt aagaatgtaa atagagataa acttcaatat gggtttaacc tgtggttaat
     2941 agagtagggt gtaactaaag ataaacttca atatgagttt aacttgtggc taatagaata
     3001 agattgtgaa taaagttata gttttagatg ggtattaacc tgttactaat agaatatgat
     3061 taggtgtaaa attatagagc tgtataagaa aatattatag atatattaaa tattagataa
     3121 taaatattta tatagataca caaaagaaaa ggcgatatga agctaaactt aatgacttca
     3181 tatcgttttt tatttgaaac tcctttgtat ttagagtgtg atttttaata ttgaggtttt
     3241 atgtgattaa gtcacagata aaaagtaagt atcttgatat aattcttata gattaataat
     3301 atagggaggt tattatgtct aataaaaaaa agaagtatgc aaatatttta gcaaatgagt
     3361 gcgttgcttg tggtagctgt ataaaagcat gtccaagaag tgctatctca gttccatgtg
     3421 gcattagtgc aaaaattaat agagatttat gtgttggatg tgggatttgt gaaaagatat
     3481 gtccagcatc tgtaattgag attataacaa tattaaaaga ggaagaaggt aagtgtcatg
     3541 aataataaaa aacattggta tgactattta tggatttttt cttcaatata tttgatattg
     3601 ggatttgtaa atattatttt cgcttggatt gggctaattt gtttctttgt tccactagct
     3661 atttctattg ttaagggaaa taaagcttac tgtaataagt attgtggaag agggcaactg
     3721 tttaatttgc ttggaaataa attgaagctg tcaagaaata gagatattcc taaatttatt
     3781 agaagtaagt ggtttagata tgggtttttg acatttttta tggtaatgtt tgccaatatg
     3841 cttttttcaa cttatttagt gtttgaagga agtagaaatt ttaaagaagt agtgactttg
     3901 ttgtggacta taaaaatgcc ttggcaatgg gcgtatcatg gaactttagt ttcaccttgg
     3961 gtggtacagt ttgcatttgg tttttatagt gttatgctta catcaactgt tcttggtttg
     4021 attactatga tattgtttaa acctcgttca tggtgtgttt attgccctat gggtactatg
     4081 actcagatga tatgtaaggc aaagagtaag tctatataga aaggctttat gtgatattta
     4141 cagttttgtt agagatgagt agtaggtttg aatatatatg acaaatatat gagtataggg
     4201 gcatagattt agtttgtgta aggtaaactg atttatgctt cttttttatg tcttagatta
     4261 ttggctaagt ggaaacaatg aatttagata ttaagaatta ttcagttatt tgaagaaaat
     4321 agaataataa ttaacattat atgaatggat attcattaca tataagccag ttaatagcaa
     4381 gatttattta atatgaaata ggtcaagtat ttaaactaaa taaggtcatg acaattaata
     4441 taagtataga tataaaaaga ttagaagtta taacttataa aaggtattct atataaatag
     4501 tatgtggaaa atagtcaaat taacttatta gaaacaaaaa atatacataa aaaaataaat
     4561 gtaaatatca aataagatac tatataaaaa tagatataag tatctttttt attattgaaa
     4621 ttatgaaaat atatttgatt tcacacaaaa aagagtgcct catgaactaa aaagttcatt
     4681 ttgagacaca cttttacagt gtcaaagaac gaagtttatc cttatccaat acttttatac
     4741 caccacgaga taaagacaca ataccttctc tagcaaaata tttcaacatt ctcgatacaa
     4801 cttctctggc actacccata tacttagcaa tttgctcatg agtcatattt atagtgctac
     4861 tgccattttt agctatctca tcaattaaaa aagatgccaa acgcttatca aaactcataa
     4921 aaagaatttg ttgcatagcc cacataacat cagaaaaacg ttcggtagct aatttatatg
     4981 aaaataactc tgcatgaata ttttctgtag ataattttgc aaaaacagag gaactaatct
     5041 gtataatatc gcagtccgtt tcagcatcta catagacatc aaaagttatt gtttttagaa
     5101 tacaggaagc tgataaaata catacatctc catcatcaag tcggaacagt gtaacctctc
     5161 gaccttcatc tgaaagtatg tatgtacgta ctgttccaga ctttataatc aaaataccaa
     5221 tacagtcact atcaccacaa tgtactggat tccctttttt gtaatgcgag gtatttgctg
     5281 aagaaattaa taattctttt tgtaagtcag taagtttatc ccaaaaaggc aagctatgtg
     5341 taagtatatc gatttcattt tgtgaaatca tacaatatct cctttcttaa attgttataa
     5401 tcccatgata caagtgaata gataaattga caagtagttt gttaatagga ttatttagtc
     5461 agatagtaat agtatgattt atgtagaaaa aatatgataa tatatattct tgctattaat
     5521 gagaaggtaa tatgttttga tgatagtagg tttgtataac taatgcatac cgtttatttt
     5581 taaaagatta agttccttat gtaaccttat agacataaaa ccagcaatta tagcagccat
     5641 caaatcagct attggttgtg catataagat accatttaac ccatagaata caggaataat
     5701 caaaattata gggataaaac agacaccttg tctacacata cctaaaaatc caccttcctt
     5761 tgcttttcct agtgcgagga ataatgtaga atacactgta tagaatccaa atagcataaa
     5821 tgaaaaccca tttgccctaa gagctttact accattttct attaatagaa tgtcaccact
     5881 tgtaaattgt gaaattatag attttgggaa gagtatcaat ataagaccaa gcactacaca
     5941 aaatattgta gtccataata tggaagtttt tattgctata tgtaatctat cgtagttctt
     6001 tgaaccaaaa ttataaccag caattggttg gaaacctttt ataaaaccaa atacaacaag
     6061 actacctaaa gacgttattc gtgttacagc acccattcca gctatcacag aatcaccata
     6121 ctttgtagcc tccatattag ttaatgtaat ggcaagacta gtcaataatt gaaatattaa
     6181 ggtaggtatg ccaattttta ggatttctga aaaaatttct tttgaaaaac agcattcgtt
     6241 aattctaaaa ctaaatatac ttttcttgct taaaatatat cctacataaa caagtgttga
     6301 agcaatctgt gagatagctg ttgcaataga agcacccctt acccccagac caaaagtata
     6361 aatgaatatt gggtctaaaa tcatattaag caaagcacct aataacatag cacacatagt
     6421 tgttttagca gctccttcac ttgtgacaat attagtcata gtgacattga atatattaaa
     6481 aatagatgac acgacataaa tgctagcata agatattgca taaggcataa tactttttgt
     6541 agctcctaac aattttaaaa ttggattgag aaaaatcata atcacaataa taactaatgt
     6601 acccactata atactactgt aaatagatgt acttaccact tttcctgctt tttcattatc
     6661 accatggcct aaaagtctgg caatatatga agcagctcca tttccaaaca ataatcctaa
     6721 tcccacaaca agctgaccta atggaaatgc aacggatata gctcccattt gacttgttcc
     6781 aagtccaccc acaaagtatg catcaaccaa attgtataat gcagttatca tcatacctat
     6841 catggtaggt aatcccatag ataacaatgc ttttgagatt ggggcagacc ctaataattc
     6901 aattcttttg ttactttctt tcatacttaa cactcctctt ctattgacat taagtctaaa
     6961 ttataatact ataaattata gtaagtatgg aaaatagtac tataatttat agtatttgtc
     7021 aatagtaaga aaactaaagg agatgatttt tatggctaca atagatttaa ttgtattggg
     7081 aatagtaaag caacaaccca agagtgctta tgatattcaa aaggcagtgg aatacaggaa
     7141 tatatcacgt tgggttaaaa taagtacacc atcaatttat aaaaaagtaa ttcaattaga
     7201 acaaaaggga tatattgaaa gtaaaactgt gaagaatgga aaaatgccag aaaaagcagt
     7261 ttattcatta actgaattag gtgagacaca ttttttagat ttaatgtttg atacatctag
     7321 caaaccaata aatattcttt tagattttaa tgctgttata gtaaatttaa atagccttac
     7381 accagaaaaa cagaaattat gtctcaataa tattgaagag aatgttcaag agttaaagaa
     7441 aactattgag gaaaatataa gtataaagac agaagtacca gacacagcaa aagcagtgtt
     7501 ggagcaacag ttggtgctag cacaagcatt ggaaacctgg ataaattctt taaaagataa
     7561 tatgggaaat tagaattaga gaagctaact taataatcat taaacaaaaa ccagcatatt
     7621 taataatgag atattagaaa aaataaaaca aatgatataa actgaaaagt atatttaaaa
     7681 taaagctcac ttaattgagg gagaatgtta aactttt
//
LOCUS       DAGQVA010000120         7270 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.123, whole genome shotgun sequence.
ACCESSION   DAGQVA010000120 DAGQVA010000000
VERSION     DAGQVA010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.123"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            171..512
                     /locus_tag="MIV85_003564"
     CDS             171..512
                     /locus_tag="MIV85_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBY2962865.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            663..1076
                     /locus_tag="MIV85_003565"
     CDS             663..1076
                     /locus_tag="MIV85_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBY2962866.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDHIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1278..1919
                     /locus_tag="MIV85_003566"
     CDS             1278..1919
                     /locus_tag="MIV85_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBY2962867.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1943..3196
                     /locus_tag="MIV85_003567"
     CDS             1943..3196
                     /locus_tag="MIV85_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBY2962868.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3242..3892
                     /locus_tag="MIV85_003568"
     CDS             3242..3892
                     /locus_tag="MIV85_003568"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBY2962869.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3943..4539
                     /locus_tag="MIV85_003569"
     CDS             3943..4539
                     /locus_tag="MIV85_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBY2962870.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4552..5391
                     /locus_tag="MIV85_003570"
     CDS             4552..5391
                     /locus_tag="MIV85_003570"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBY2962871.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKKVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5636..6790
                     /locus_tag="MIV85_003571"
     CDS             5636..6790
                     /locus_tag="MIV85_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBY2962872.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7096..>7270
                     /locus_tag="MIV85_003572"
     CDS             7096..>7270
                     /locus_tag="MIV85_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBY2962873.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEI"
BASE COUNT         3027 a          679 c         1260 g         2304 t
ORIGIN      
        1 aaaaagtctt tttaacttta aaaattaatg ttaaaaaata aacttataca ttaatattaa
       61 taataattat ttaaatatct taagtaaatc agtcttacat atatttccga tagattatat
      121 tgataaaaaa cactaaaatt aaattaataa aagtacttgg agggatggaa atgaaagagg
      181 aaaattttat taatgttgaa tacgaggata aacgtttttc aattaatagt aaagaagttt
      241 tgtacataga aaagcaagag tatgaagtaa agatttatac tgaaagtggt aattatgaag
      301 ttggagaaaa tgctccttgt ataagaaaac tattgaaaga agaaaatttt ttcaaatgca
      361 gtaatagtta tattgtaaat ctagacaagt gtgaatttta tctcagcaat aattgtattt
      421 ttgtgaataa taattttata agaattttag gttcagaaag aaaaaagaaa ttaaaaaaga
      481 aattagaaaa attatatgat tatgaagatt aatattggga ggctgtattt tatacagcct
      541 ctttatttat tgattgtatt attaataaat tttaaattat gataaaatat aaaacaagta
      601 acttatttca gaataaaata ctttttaaaa gaaagggacg agatatggga gattataata
      661 aaatgcttga attaaagaat aacttaggta tcagtgaaag aaagttaaaa tatccttgta
      721 tctataaaca tttcaaaggg aaatattatg ctacaatggg tcttagcaag gctattgatc
      781 atatagaaaa catatgtgaa atatatggta aagaaaattt aatccaaaac agaaataaat
      841 ataaattagt tattagacat actgaaagag aagaagatat ctatgtttat agggatttag
      901 atggaaactt ttatcataaa aaagaagaag atactaatga tttagtttta tacaagacct
      961 tatatgatga tacaggaata tttgcaagac ctttggatat gtttttagaa aaagtagata
     1021 cagataagta tgtcaattca attcaagaat acagatttga agaagtatat aaataatata
     1081 agagaaatat gtttataaat ttagaaaaat tctttaacag tacaataatt tgcagaaata
     1141 caaatgagat ttattgtaaa taatatgtta gattagatta taaaatagaa acaaagtaaa
     1201 gtattatatg atataattaa gttttgagaa gtgataattt atatttaata aaaaataggc
     1261 atatattagg aggacatatg ggaaatactt tttatatagt aagacatgga caaacggatt
     1321 ggaatatatt gggaaaaaca caaggtcatg gtaattctga ccttacgcct caaggtatag
     1381 aacaggcaaa agaactttct gaagatattg gcaagtattc aattgattat atttttagta
     1441 gcgaccttgg gagagcaatg caaacagctc aaattttagg agataagctc aatattgaag
     1501 ttcaaaaaac tgaggcactt agagaaatgg gattcggagt ttgggaaggc cttttaataa
     1561 aagaaattca aaaagattat tcagatatat atgcaacatg gagaaatgaa ccacacttag
     1621 taaatatacc agaaggcgaa actcttaaga ttataaagga aagagtagat gcttttataa
     1681 aggaactaaa tgaaaaatat gataataaaa atataattct tgttacacat tcaattacat
     1741 tgagggttat gttgttgtca tttttagaat caggtatgga aaatatatat agaattaagc
     1801 aagataatac tgctttaaat atagtagaat ttaaagatta tgggcctgtt atagtaaaaa
     1861 tgaatgatac aagtcatata aaaaatcatg taaagataaa taattctgca ctggagtagg
     1921 aatcaattat aaggagaaat ttatgagtaa agttatagta gttggtggag gagcttctgg
     1981 aatgatggca gctttgtcag cttcaaaaaa caataatgaa gtaatattag ttgagagaaa
     2041 tggagaatta ggaagaaaac ttagggcaac tggtggcggt agatgcaatt ttaccaataa
     2101 tagagagata gaagattttt ttgataaagt tgtcagtaat aaaaaatttc tctatagtag
     2161 tttctataca tttacaaata aagaccttat ttcgtatttt gaaagtagaa atttggaata
     2221 taagattgaa gaagaaaatg accacaaagt atacactaaa aatgataaat ctatagaagt
     2281 aatagaagta ttaaataaag atttactcaa tcacaatgta aagataatgt ataataagaa
     2341 agttatagat attataactg aagaaattgc tctaaaagat gattctaata aggacaagtc
     2401 aaagtatcta ataaaaggga ttattttaga taatggagat aaaatactag gagacaaggt
     2461 tattatatca actggaggag tgagttattc aaagacgggt tcagatggtt caatgtataa
     2521 gattcttaaa aagcatggac atacattaaa caaactatat cctgctttag ttccacttac
     2581 aatagaggaa aaatggatta aagatttaca aggaatatcc atgaagaatg tggaaatatc
     2641 ttgtaagatt aagaaaagga aaatatcaaa atctggagac atgctatttg cccattttgg
     2701 gataacagga ccttgtgttc ttataatgtc ttcttatatt aacaagatta ttgaaaagga
     2761 aaaggtagaa ttaaatatag atttcttacc aaatttaagt actgatgaaa tctctagtat
     2821 aatcagagca tttccaaata aaaatgttct aaataatctt aagcaaatac tacctcaaaa
     2881 tttcttaaaa gagatttttt ctctattatc tttagttgat aaaaaggcaa gtgatttgtc
     2941 taaggcagat gaaattagaa ttattgagta tataaaaaat atgaagctaa cttgtaatgg
     3001 gactacaggt ataaacactg gtatggttac ttctggtggt atttcagtta aagaaattaa
     3061 ttcttctact atggaatcta aattagttaa gaacttattt tttacaggtg aagtaattga
     3121 tatagatgca gaaactggtg gatataattt acaaatagca ttttcaactg gatatcttgc
     3181 gggtataagt gtataaatat aattttttaa taattaaata tgaataaata gaggtgtata
     3241 tatgggtaat ttagttatag ctgtagatgg tccagcagga gctggaaaaa gtacaatagc
     3301 caagatagta gcaaaaaagc taaatataaa ttatatagat acaggtgcta tgtacagagc
     3361 agttacttat aagtgtttaa aaagtggtat tgatgtcaat aatgaaaaag aagttattca
     3421 aatagctgaa aattcggata tagattttaa agataacaat atatatttgg acaaagaagt
     3481 tataaatgaa gaaataagaa caatagaagt aagcaataat gtttctaatg tagcaaaaat
     3541 aaaagaagta agacagttga tggttgaagt tcaacgaaaa ataggaatga aaaattcagt
     3601 aatactagat ggtagagata taggttcata tgttttccca gatgcagatt acaaattctt
     3661 tttagtagct actccagaag aaagaggaaa tagacgctat aaagaacttt gtaataaagg
     3721 atataatact actttagaag aagtaattga ggatataata agacgagatg aaattgattc
     3781 aaatagagaa tttgcaccat tggtaaaagc taatgatgca ctagaaatag atactacagg
     3841 aaaaactata gaagaagttg tagaagaagt tgtatctaaa ataaatcttt agttttttat
     3901 gcatcataat gaaaataaat gtagtgttga agggagataa acgtgaattt ttatagattt
     3961 gtaataaata tttttaaggg tttttctaaa atatttttta aatatgaagt tataggtgca
     4021 gagaatattc cagatagagg aaatatagta atagcatcaa atcataaatc gaatcttgac
     4081 cctatattct tggctgctgc catagaaaat agagaaatag ctgcaattgc aaagaaagaa
     4141 ttgtttaaag taaaaccatt gggatttata ttaaaaaaat tgcatgttat gcctataaat
     4201 agagaaaaac cagatgtatc tacaataaaa actattttaa ggtcagttag agacggttat
     4261 gtattaggaa tatttccaga gggtactaga ataaaaggag attcttttgg taaggctaag
     4321 gcaggtcttt ctgtatttac aataaaaagt aaatctaaag ttgttccagt atcaataata
     4381 tctaaatata aactttttag taaagtaatt gtatatattg gagaaccaat atcatttgaa
     4441 gaacatttta aggaaaaatt gagtaatgat gaccatgaaa ggatatcaca agagatttta
     4501 gaagtgataa aacaaaatta ctttaaatat tcaaaataag ggggtaaagt tatgaacata
     4561 aaaatagcaa aaaatgctgg cttttgtttt ggagtaaaaa gagcaatgaa aatggcatgg
     4621 gatgaagttg aaaaaaatga ttctggcata tatgctttag gtcctcttat tcataacaag
     4681 caagcagtag caaaatatga agaaaaaggt cttaagactg tgaatgaaat tgatacaata
     4741 ccaaatcatg aaaatatgat aataaggtct catggagttc ctgaaaatat atataaggaa
     4801 gccaaagata aaaaattaaa aattgtggat actacatgtc catttgtaaa gaaaatacat
     4861 acagtagtaa gtgaatatca taataaaggc tatgaaataa tagttattgg agatatgaag
     4921 catccagaag ttataggtat aaatggatgg tgtgaaaatt cagctataat aataaagacc
     4981 ttagaacaaa tggaaaatat ggaatttgat aactccaaaa gatattgtct tgttgcacag
     5041 actacaataa atccagagtt gtatataagt atagttaata aactatcaga taaattagaa
     5101 gaaatagtat ttaatgatac aatttgttca gctacaaaaa caagacaaga atcagctaaa
     5161 gagttagcta aaaaagttga ttgtatgata gttataggag gtaaacacag ttcaaatact
     5221 caaaagttag taaaggtttg tgaagactta gtaccaactt ttgcaataga gactaaagat
     5281 gaattggatg taaatacgct taaaaaatat aaaaatttgg gtattacagc aggggcatct
     5341 acacctaatt ggataataga agaagttgta acattccttg aaaatttata atttgatagg
     5401 taataaaaat aggtggacat tgttataatt tatcataata tccacctttg atttcatatt
     5461 acatgtggta aatagataac ctaatatcaa aaagtgtgta tcttaagatg aaaaactaag
     5521 agtataagat gcgcactttt taatattaga aattcaaaag aaatattgat attgattatc
     5581 aatagaaaat agaatataat ataattgttg caaaattagt ctaggaggta aattaatgga
     5641 aatgttgata tccgcttctg aagaggcgtt tttacatgta ggttctatga ttggattttt
     5701 tattttgtta tttggatata ttaattataa aactagtgga aattttacta atatcatatc
     5761 aaaaaacaga aaatttcaac ccttaatagg tgctttaatt ggagctatac caggttgtgg
     5821 cggaagtttg gcaataatgc cattgtatat aaatggaaaa ttaagctttg gagcaataat
     5881 tgcaagttta atagctagta tgggagatgc agcatttgta cttatttcat caaatattaa
     5941 aatgtatttt tttgtcacta tagttagtac aattacagga ataataactg gacaattagt
     6001 ggattacttt aaactagaag aaaaattagg gttaaaaaac cgtagaaaat cagataaata
     6061 tgatataagt aaaaataacc ctaaagaaaa taaagaacaa cataatcatg atgaaataat
     6121 tttagacact ctagctaaat ctcatggaaa tacaaataga cttgcattta taataacaca
     6181 tggaaaggga tataaaattt atataggaat tatagtaatc ggttttatat ttatgtcact
     6241 tgctcactct ggacttaatc ttcctataat tgagaagtta cattcattgg aagaagtaat
     6301 agcagtgatt ggaatattat tttcaataat ttatatgtgg tgttttaaaa aggtatttaa
     6361 aaattctaat caaaaagagg aagaaaataa aaagatttct ttgcgagaaa tgcttatcca
     6421 ttctgttgga gaaatatcat ttgtaattac atggattttt attgcatatc ttatttacga
     6481 tttgataata ttaattttag gtggagatga atacttagtt aaattagtat tatcaacagg
     6541 tgtaataagt gtatttatag gtgcaggtct tggacttatt ccaggttgtg ggatacaaat
     6601 tgtgcttatg tcattttatt tgaagggaac tataccactt ggtgcagtga tagccaactc
     6661 tatttctcaa gatggagatg cacttttccc acttttagca atggataaaa aatcttcttt
     6721 atgggctatg attattacta ctataccagc aatacttgta ggtatgatag tttatgcatt
     6781 tttaggttaa atataattat gaataaagaa gtattaaaaa aataataaag cacataaatt
     6841 tatttataag aatagtgaag attaaatata aaaataaaaa attcaatatg aattaaatta
     6901 ttgcttaaat attaatgaga acatgggaga taatattatt cctcatgttc tctctattta
     6961 attaaaggaa ttatggaaca aatttcaagt gatactttct atcaaaactc atatataata
     7021 tatattaata aattaaacta taatacgtaa tacagtcagt atattgatat aaaaaactta
     7081 ggaggagttg taaaaatggg taatttaaaa agacagtgtg atgtttcaag tggaagagaa
     7141 aaagctgaca ttgtactaaa aaatgggaca atcataaatg tatttacaga agagttaata
     7201 acaggagatg tagcaatagt aggagacact atcgttggaa ttggcgatta caagggcaat
     7261 gtagaaattg
//
LOCUS       DAGQVA010000121         6780 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.125, whole genome shotgun sequence.
ACCESSION   DAGQVA010000121 DAGQVA010000000
VERSION     DAGQVA010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6780
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.125"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(230..1192)
                     /locus_tag="MIV85_003573"
     CDS             complement(230..1192)
                     /locus_tag="MIV85_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBY2962874.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            1383..1934
                     /locus_tag="MIV85_003574"
     CDS             1383..1934
                     /locus_tag="MIV85_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962875.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     repeat_region   3169..4318
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3235..3263
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
     gene            4965..6236
                     /locus_tag="MIV85_003575"
     CDS             4965..6236
                     /locus_tag="MIV85_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBY2962876.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
BASE COUNT         2538 a          957 c          759 g         2526 t
ORIGIN      
        1 tatgtattat tccaagttat gatgtataaa tgcaaaaaca catactcttt tttattgcat
       61 agctaatcat caatatctat atagcttaat acttataagt aggatactcc atatttacaa
      121 aataaaaaag tatctccttt ataactttca aaatttacat tgagatactt tttataattt
      181 aaatctatat acttaattta aaaaacattg cataactatt gtgctattat tacaattctt
      241 catataaatc agtacttaaa tattttaaac cactatcatt aagagttaaa actatatttt
      301 ttcctttttc actgctcttt aacaacttaa ttgctgcaca tacatttgcc cctgaagaaa
      361 atcctgcaaa tacaccttct aatttagcta attttcttgc tacatcagtt gcctcctcgt
      421 ctgtaacttg aatataacca tcaataagtt tcttgtctac taatggcaaa tccatagaat
      481 atcctccacc ttgtatttta tgcccttggt cagttatttc tttacctgaa taaattgctg
      541 ctgtttcagg ttcaacaaca taacatttga tagaagaatt atgtttttta agtgtttttg
      601 aacatcctgc aaaagtacta ccacttccaa gaaaatctac aaatacatca atatttccat
      661 ccaattgttc ccacatttct tctgctgtat acttttcatg tgcatgatta caagcttcta
      721 aattaaattg gtctgctcta aatgcatttc tttcttttgc tattttttga gcctcaattt
      781 ctacaagtgc caaatcttca ccagatacct gtccatgaac tgaattaggc atttggtcta
      841 caagaactac ttcagcacct aaagctttca tcattcttgc tctttccata gaatttcctt
      901 ttgacataca cgctataaat ttatatcctt tacatgcaca agctattgct agtcctgttc
      961 cagtattacc acttgttaat tccacaactg cttgacctgg aactaataaa cctgcatttt
     1021 ctgcttcggt aatcatttgt aatgctacac ggtccttttt actaaatccc ggatttaagt
     1081 attccatctt tgcataaata ttaccttgaa ctccaaattc atctgctatt ttggataaat
     1141 gtaacatatg agtattgcct atagcctctg taacattatt aagtacacgc attacaattc
     1201 ccccttaatc tctcaactat catccgttga aaaacaactc tttatgcagt ataatttata
     1261 ttacggatgt acagtgtatt taacgttcat tatattatac atttgtaaat tataaataat
     1321 gttaaataaa ttatacattc gtaaattata tttgtcaata atttacattt taaggagcta
     1381 ctatgagtat taatactgtt attgctaaaa atttaaatag attacgtaat gaacgtaact
     1441 taagtctagg tcaacttgct gaattatctg gcgtaagtaa agtaatgctt tctcaaattg
     1501 aaaagggaga ctcaaaccca acagtaaaca caatttggaa aattgcaagt ggactaaatg
     1561 ttccatatac tgcaatactg gaacaacctc aaaatgaaac ttttattgta tcaaaaactg
     1621 atatagatgt acaagtttca gaaaataaag attatcgtct ttattgttat tatcccaata
     1681 caccaactag aaacttcgaa ttatttcaaa tggaattaga agaaggtcat agttatacat
     1741 ctgttggtca ttctgaaaaa tcacaggaat atattatgat tatagaaggt caattaaaat
     1801 tagaagtaaa tgactctatt tatcaactta gagaaaatga ctctatttgt ttttcagctg
     1861 aatcaattca tacataccat aatcaaggag aaaaaacatt gaaagcagta ataataaatt
     1921 attatccagt ttagccatgc catttaataa tagaataatt attttctata caaaaagata
     1981 aatcctttga ttaggattta tcttttttat tttatttttc tttataaatt cattatatat
     2041 ctttacactt ttatcaatta tgttataata agcttatata aaagttttat atttttgaca
     2101 aatggagtac aaaatactcc tttttctttt ttaccattgt gataattatt tagttagtat
     2161 taaaatatta tcacttaaaa caaatacaaa acgtctctta tatgtacatt tttcattgtt
     2221 gtaataatga tttgtgtatg tatttctcac aattggagtg cttatgcact ctttttaaat
     2281 acctctatta ccataaacta aaagctattt tattatccct tttagtttat ttttaagtag
     2341 ttaaataaat tattttatat ttttttcttc atttatatga aacttttgtt ttatcactat
     2401 atgcacttta tatttactac aaataacaca taagcttact tttatcataa gactcctata
     2461 tctaaatata atttaagagg ttaaataatt gaatagtata ttaaaacata atggtaatga
     2521 caaaaatata aaaatcttta tagtcataaa ttttatctta tcatttttat cctctccatt
     2581 aaaataatta tcttgataaa atgtagctct attttgataa cctgttttta aaactccatt
     2641 ttgaattaac agcaatataa aaaagattgc taataaaata aagttataat ttttttcttt
     2701 taatctaaaa ttagctataa taacaatgaa actatataaa gcatataaaa tttttttcat
     2761 aaaaaacacc taaattctat atttgtattt tatattgagc caaatctaat ttctgtatat
     2821 ttattaagtg tagttctagt tcctattgta gtagcattaa atatttttta atttttattt
     2881 tcaaagggca tctccttata tttaaattat agtatgaata ttcataaatt tcaatctatt
     2941 tataaggtaa ttatttttta tatctaatat cttgtcatta agttttatta tatatattta
     3001 taaatttttc aatacttttt ataattattc tacttttata ttttaatcat taaaactaaa
     3061 gtcaatgtta tctggtaatt atttactaca aatgctaaaa aataattata ttttaaagga
     3121 taaaatgctg tataaattat tggggtattt tacctatact tgttgcaaat ttacatacca
     3181 cgtagttaat ataaaacaag atgtttttaa aaataaactt aatatagata ttgaatttac
     3241 ataccacata gttaatataa aactttaatc atatatcaga taggtcacaa cttaagagtg
     3301 atttacatac cacatagtta atataaaaca acttctcata ttccagataa ttgttatttt
     3361 acgaaattta cataccacat agttaatata aaacctgtag atttgcctgt ttcgatattg
     3421 ctcatgtgtg aatttacata ccacatagtt aatataaaac tctcttgttt cttctgttaa
     3481 ttttattata ccttcattat ttacatacca catagttaat ataaaacgcg ttatattgtt
     3541 gtataaaacc gattaaagtt caatttacat accacatagt taatataaaa cttgcaacat
     3601 attgttttat cgttgctggg tctttaaaac catttacata ccacatagtt aatataaaac
     3661 taagcgatat tagagagcgc aaggcatagc ggagcaaatt tacataccac atagttaata
     3721 taaaacttta attttaacca ccccctttca ctaataaaaa aagatttaca taccacatag
     3781 ttaatataaa acaagacgct atacaagagg taatttgaaa gcaatctaat ttacatacca
     3841 catagttaat ataaaacgtt gcatatgtat gtctaagagc atgaaattta attttattta
     3901 cataccacat agttaatata aaacttctat taagtgtaag caaaacgctt ggaatatgaa
     3961 atttacatac cacatagtta atataaaact tatacacaaa tacaacttga agaagcgcta
     4021 aagagattta cataccacat agttaatata aaacctaatg agtacataga taaacgtaca
     4081 ggagaggtta atttacatac cacatagtta atataaaacg ttgataattt tcgtttgtat
     4141 actttttata atttaaaatt tacataccac atagttaata taaaacataa agatttagaa
     4201 aaagaaaaag ttaaaatttt ggaatttaca taccacatag ttaatataaa acttttcctg
     4261 ttaagttgat gtttgcaact ttaactgcta tttacatacc acatagttaa tataaaaccc
     4321 caaaataaac taagtatttt cagtacttac acacatacaa ctctctcaaa tttgcagtga
     4381 accatgagta gtgcaattga taacatttat cacacaccct caatccctta cattgcaact
     4441 gttaaaccct actttatcaa aaatatcgct cactgcaaaa tttatatatt tttattatat
     4501 cataaaattc aaactataaa attaaaatgg aataatttat caatttaaga acacctacat
     4561 atttgtaaat acttactata ttatctattc taataattct tcttctagct ggaactaata
     4621 taaaaatcat ctctgaaaga ttaggacata ctaatataaa aataactatg aatagatatt
     4681 ttcttgtttt aaacgatatg gataaaaaag cttctgaaaa tataatcaaa gttctcttta
     4741 aataacattc cattttatgt aagtaggcat tatatttttc ttaaatgtca cttaaatgtc
     4801 agttatatat aataatagta aacaactgta tttcactaat atttgctatt atctaatagt
     4861 atttatagtt tagatttgat ataatacatg tggtaaaatt ttgatttgta aaacaaaatt
     4921 ttacctacat atattaaaac aaatttaaaa ctaaggagac ctatatgtta aaagtattaa
     4981 aaggaaatat aatttttaca aaaacttcag aaactttcac agtatttgaa aatagttata
     5041 ttatactgga aaaaggtaaa gtaaagggaa tatttaaaga gatacctaag gaatacaaaa
     5101 acctaaaagt agtagattac actgataagc ttataatacc tggtatgaat gacctccatg
     5161 cccatgcctc tcaatttaaa aatcttggaa tggctatgga taaagagctt ttgccatggc
     5221 ttgaaactta tacatttcca gaagaatcaa attataaaga tatagaatat gcaacaaaaa
     5281 tgtataaaaa atttgtaaaa gaactttgga aatctggaac tacaagaata gcagtgtttg
     5341 caacagtaca taaagaagcc tctatgaaac ttatggatat attcaaagaa gttggtcttg
     5401 gagcatacgt tggtaaagta aatatgaata tgaattgccc tgatacttta ttagaaaaca
     5461 ctcaggattc tattactgat acagaagaaa ttataaataa gtatagtgat acagattcta
     5521 ttgtaaaacc aataataaca cctagattta taccaagctg tacaagtgaa cttttaaaag
     5581 gtttaggaga tttatgttta aaatataata ttcctattca atcacactta tctgaaaatt
     5641 atgatgagat tgaatgggtt agaagtctag aacctgaatc taaattctat ggagatgcat
     5701 ataatagata taatttattt ggtcaaactc ctactttaat ggctcattgt gttcattgtt
     5761 ctcaggatga aatagattta atgagagaaa ataatgttat ggcagttcac tgtccagctt
     5821 ctaactttaa tgttggtagt ggtgctatgc ctatcagaaa attaatcgat aataatatta
     5881 gattagcact tggatcagat ataagcggtg gacatacatt gtcaatattt aaagcaatgg
     5941 tatctgcaat acaattatct aaattatatt gggttaattc tggtaagaag tataatttct
     6001 tatctttatc tgaggctttt tatattgcaa ccaaaagtgg tggaagtttc tttggaaaag
     6061 ttggtagctt tgaagaaggt tatgattttg atgcattgat tattgatgat tcaaatttaa
     6121 atcatgacaa ttattctata cttgaaagac ttgaaagatt tatctatgtt ggtgatgata
     6181 gaaatatcat tcatagatat gtatgtggaa aactaattga agaacctaat atataattat
     6241 aataaaaatt ttaattatat attatggtta atttatacaa ctataattaa taaaagagta
     6301 tattttaaat ctaaaagcta taggttgaaa catactcttt ttattttgtt tatttatagc
     6361 tttagttatt aatcatatat aaatctacaa aacgtattcc tagtaactta tattttttga
     6421 tatctacaat cataagacta tattattgga ttcatacctc aaaaatattg ccttctgaac
     6481 attattatat tcaaagctat gttaatttac aatgatatat cctaacatgt attgattaaa
     6541 aaaaattaaa acttgctttt catctcctat atctaaagaa gtggtattta gaataaacta
     6601 ttgtaatatt aaagttgaaa ttttctagtt tatttactct atagcaccat attttaatac
     6661 tattaagtaa aaatgtagtt aaaatatata ctaatatccc tgaaataagt atttcttttt
     6721 tatttagcac acttattcgt aaggtattag ttattatatt tccaaattat agaataaata
//
LOCUS       DAGQVA010000122         6773 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.126, whole genome shotgun sequence.
ACCESSION   DAGQVA010000122 DAGQVA010000000
VERSION     DAGQVA010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6773
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.126"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            240..1067
                     /locus_tag="MIV85_003576"
     CDS             240..1067
                     /locus_tag="MIV85_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBY2962877.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGSGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2067..2530
                     /locus_tag="MIV85_003577"
                     /pseudo
     CDS             2067..2530
                     /locus_tag="MIV85_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(2797..3441)
                     /locus_tag="MIV85_003578"
     CDS             complement(2797..3441)
                     /locus_tag="MIV85_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962878.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3371..4660)
                     /locus_tag="MIV85_003579"
     CDS             complement(3371..4660)
                     /locus_tag="MIV85_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962879.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4657..5529)
                     /locus_tag="MIV85_003580"
     CDS             complement(4657..5529)
                     /locus_tag="MIV85_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962880.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(6058..6549)
                     /locus_tag="MIV85_003581"
     CDS             complement(6058..6549)
                     /locus_tag="MIV85_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBY2962881.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT         2457 a          934 c          807 g         2575 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatgt
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagtgggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 agatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 gtggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattataaa
     1141 atcagagtgt ggaaatattt atgtgtattc tttaaataaa aatttccaca ttctgtaaag
     1201 ttattatact tgatatataa aattcaattt aggaacatag tctaacattt ataaacatat
     1261 taaggtaatg atttctcttg gtagttattc tcatatctta ttctttgatt atatttatct
     1321 tattcctagc ccttatgtca tattatattt cttatcttat tatttataat tagcattaac
     1381 ttatctaaaa tcttgtattt ttttaatagt aaagtttaca tctatattaa tttcataaaa
     1441 caatcaaggt agtcaagaga ttcaacttta tttgatttta aaaatttaag tgaatttgtt
     1501 cttatacaca cctttttaaa attatatctg tagaaaatat catttagagc tataattaaa
     1561 ttaacttatt aaattttaga aaatttatta aaaaatataa gttaaattaa tatttttaaa
     1621 gattcttttt tgtaactact agaacactaa tttagtagtt attgtatctc taaagtttaa
     1681 gcatggatag atatacattt gataatttgc ctataattta cctactactt ggattattgg
     1741 agcaaataca atatattaat aataagttcc taaaaccaat aaattaacta atacacataa
     1801 agatattgat gttgattata caactataag aaacggattt aacagaattt aatcaagcta
     1861 agaaattata tatatcgtga tgtttttgaa ttagaaggtg attcaaaatt agtttatagt
     1921 cttctgtgaa tccaataaaa agtacagggt acaagaattg ttagtaaaat ttttaaagat
     1981 tttatggata aatataaata gttttactta ttttctaaaa ctttaaaata ccattaatta
     2041 ccttaaatat tttaatagga ggacatatga atttaaataa agttaaattt actgaagaac
     2101 atgctattga agttactaat tggaaatatg aaggtaaata ttcaatatac aatctacctc
     2161 catgggagga aattaaaaag aagaattttt cactagcaaa agaagataaa agaaaaaatt
     2221 ttataagttt tataaatgac aataaagaat tgataggttt tataaactta ttagatgaag
     2281 gaagctctgt attctttggt attggttgaa accgaattat tgtggaatgg gaattggtaa
     2341 agaaataatt agcctaggat tacaagaatg tagaaataaa tatagtacta aaccaattgt
     2401 attaaatgta agaacctgga acatgagagc tgtaaaatgt tatgagtctc aaggatttaa
     2461 aatagttgag actaaggtac aaaaaacgca tttaggagat ggagaatttt ttgttatgag
     2521 gtatcaatag tttataacaa tagtcctatt gttaatacaa caattaaaat gaaaaaatac
     2581 atatgtgtag gtcatagcaa taagtgtctt tgaaatataa atttgagagc ttttgataaa
     2641 attcggtata catatatatt ttatactacg gatatataaa tctatctaca tacataaaga
     2701 gattgtaagt aggtttgtgt atataaaaat agatttatat ttcataaatg tactttttat
     2761 ttgcattacc tttattttat ctaagctctc attttattat ctaatcttcc tttttactgg
     2821 ttttattaag agagatgcaa ttatcaacac aacacttcca agtatcagcc aatatttctc
     2881 atcaaaacta ccttgactca tagacattat aaaaaatttt ccaacatact tgcctttagt
     2941 catcatattt aaaattaaat atcctataga tatcatataa cctatgattg tattattaaa
     3001 taaatttgag aaaaacattc ctaaacttcc tataaacata gctgatgcga aacttccaat
     3061 aatatactca actactggaa aattacatcc aagatatatt aaaacattta caaaacctat
     3121 gattaatacc actataccta taattgacat cagtatccta attaattgta caataacttg
     3181 agataatgct tttgaagata ctatctcatc aatttctttt gattgctcta gcgaaaatac
     3241 aggtaccaac attactatcc ctattattgc aacataattt tctaaacata tagctgttga
     3301 aattctgtct aaattagcta ctccttgtat tagaggaatc atacatagca atataattga
     3361 acatattaaa ttagttaaag tgcttaattt gaagttttct tttattagaa ctaaacagtt
     3421 ttgaaaactt tgcccaaaca tcaagattcc cccttctttt ttgctcatat aagaatatag
     3481 ctaacaaaac aagcaccaat gctcccaaac ttatcacaat tctattaatc ataatttgat
     3541 tgaagttttg tataataata tccccattta atacactatt atgtcttatc attagcccca
     3601 ttgttgaata atcacctttg agtcctgtag aatttatact gtaaagccac caaattaatt
     3661 gcacaataat tgctactggt gtatctgtta atatagtaat actcattcct acagctgtaa
     3721 ctatcataag agttggtagt atccaccata atgtatattt tataaatgct aagttatcaa
     3781 tagatatacc tttatcttta gcaaagaaaa tcaaaggaag taaatctttc atacctaaaa
     3841 ttaatacagg caatatcatc ataaagacaa gtgcaaaata tcttgataaa actattttgc
     3901 atgaagatac ttgttttgaa taaataatct ctctcattct tgaacgctta tctttaagtg
     3961 acataaaaac tgccacaaat actggaaata tacttaaaac tatacctata taatcgcaaa
     4021 aaattcttgc atacccatta ctaactttat ctttttgtat tgtatagttg taattcttca
     4081 tagcttcatc ataggtaact ggaactactc caaatctttg taacttgtca aaagcatatg
     4141 cagaccctcc tcctaaaatg tcgtctactc tttgcattat ttcttcaaat ctttcaagag
     4201 atactttaga ataatctatt tttatacttt catcagtttt ccaaagtgaa tttatttcgc
     4261 taatactttt accagttatt tcttctatat atttttctat ggtcttcgtt ttattttggt
     4321 ctaattttat atacttaact acccctgttg gatacgttgt atatgtgttt ttttgatatt
     4381 ctctaattag gtttatagtt gcatttggaa tgactttttc tgttttcata gattcttttt
     4441 gaccatatgg atattgattg tgtacagagt aatattcctc aatattctct actttttgtg
     4501 gagcaactaa tggatttcca tcattaggaa tatttttact tacatcattt gaaactgaac
     4561 ttccaagttg agaaatatag aaaaaaacta aaactacaat aaaaatataa tatatcatac
     4621 tctttaatat atttttacat tcttttataa atagattcat atattatctc ctcccattat
     4681 aagcatatag ccatcttcaa tagttggatt acaatttact gctgtctcaa aaggtttatc
     4741 atctgatata atcctaagta tagcctttcc accatgagtc aacattccta taactataaa
     4801 tctacttttt atattttcaa tatctttttt atctacttca atactatata ctttcccttc
     4861 agctagtttt gctaatgctt ctgttgagcc attgtatatg acttttccac tattcaatat
     4921 agctacgttt tcacatgtag cttctatatc tccaacaata tgtgtagata aaataacgat
     4981 tctatcattt gcaatttcgc atagtaaatt tctaaatctt atacgttctt ctgggtcaag
     5041 acctgctgtc ggctcatcta ctattaaaac tctgggatta tgaattaatg cttgtgctat
     5101 cccaagcctt ctattcatac ctccagataa agattttact ttcacatttt gataattagt
     5161 aaggtttact ttgcttaata actttgctat aatttttctt ctttttctta gtggtatatc
     5221 cgataaaact gctaaataat ccattgcttt atatactgtc atgttaggat acattgaaaa
     5281 gtcttgtggc aaataaccaa ccatatttct aatttcctta gtattctcaa taggaactcc
     5341 acacatatgt attgaacctt ctgtttttga taataaagtg gctaaaattc tcataaatgt
     5401 ggtttttcct gctccatttc ttcctaaaag accaaacata ccactgtcga tttcaagatt
     5461 tatattatca agagcttgtt ttttcccaaa tcttttacta agattggata ctgctatttt
     5521 catttccata tataaataca cccccagaaa caattttata gaattttatt tttataaatt
     5581 tttactgtat tttcataata aattctaaaa cttaagatat tatttataaa tttctaaatt
     5641 ttttctaaag attttaattt ttctgttttt aattaaatta aagtatcttt gtttctgaaa
     5701 ttttttaagt ttatgaagtt ataatttaat atatatttat tttatttgtg agtctatttt
     5761 tatatataat gaaaaatgtg ataagtatcc aaaagaatta ctggatataa taggataggg
     5821 tatttagcct tttaagataa ataaaaatat ctgcaactat atattgcaaa aatttaaaac
     5881 taatttatat atgctaatat aaatatttat aaagacataa gacaaattta cctacagatt
     5941 taaatttaac ttatatattt taaaaggcta atataatatg tattttcttc tatacaatca
     6001 aaaggcttca tatctaagat atgtgatgac actaatattc acaattttta gtaattatca
     6061 cattataaaa aatattacag ctagtccatc attagatgct tcttgtataa actttttaag
     6121 ctcaattaga tttgcccata catattcaaa aaaatcatct tcactctcat cattcataac
     6181 aggataaata ttattttcta acatctcatt aatattaaat ctttttctaa atgcttgttc
     6241 ttccaaactg ttcattgctt ttgatagttt ttttacatca tttgctgtaa tcaacatgac
     6301 aggaaattct ccatcaattt ccataagtat gtttccactt agtactaatt tgctaaatat
     6361 attatcatca tctccaccaa aaggacaacc tgtcaaagta aagtgaatgg catgccatgc
     6421 tttatcaata ttgatagtac tattttcgtt ggcatcttca aaaacaaaat cttgtaaatt
     6481 ttcttctgct tgctgtaatt taaaaacatt ctcttcactt attttagtat aacatcctat
     6541 cattcccata attacattcc tcctaagtag cgttttttta attgtaactt ataattaaac
     6601 ttagttacaa taaaatatat tgagaaaagt attatttcat cttaaattta aatacctata
     6661 ttatcaacta aaattctgtg tttatagcgt aagtattatt ttttcctaaa aattaaatga
     6721 atcagaggtt ctataggcaa tattgactat aaataagaac tattactttt taa
//
LOCUS       DAGQVA010000123         6509 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.127, whole genome shotgun sequence.
ACCESSION   DAGQVA010000123 DAGQVA010000000
VERSION     DAGQVA010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.127"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            86..1255
                     /locus_tag="MIV85_003582"
     CDS             86..1255
                     /locus_tag="MIV85_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBY2962882.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(1418..1960)
                     /locus_tag="MIV85_003583"
     CDS             complement(1418..1960)
                     /locus_tag="MIV85_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBY2962883.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2108..2392)
                     /locus_tag="MIV85_003584"
     CDS             complement(2108..2392)
                     /locus_tag="MIV85_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBY2962884.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(2455..3219)
                     /locus_tag="MIV85_003585"
     CDS             complement(2455..3219)
                     /locus_tag="MIV85_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBY2962885.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(3501..3767)
                     /locus_tag="MIV85_003586"
     CDS             complement(3501..3767)
                     /locus_tag="MIV85_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBY2962886.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(3809..4618)
                     /locus_tag="MIV85_003587"
     CDS             complement(3809..4618)
                     /locus_tag="MIV85_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962887.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIEELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            4931..5212
                     /locus_tag="MIV85_003588"
     CDS             4931..5212
                     /locus_tag="MIV85_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962888.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            5476..5730
                     /locus_tag="MIV85_003589"
     CDS             5476..5730
                     /locus_tag="MIV85_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962889.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            5775..6098
                     /locus_tag="MIV85_003590"
     CDS             5775..6098
                     /locus_tag="MIV85_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962890.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
BASE COUNT         2380 a          774 c          919 g         2436 t
ORIGIN      
        1 gaattagtaa gacatatttt agtatgcaaa attctgtgaa gcaggaaccc tgtgacttta
       61 gtcatgggag gttcagggta gaaagataaa tgaactttgt aaagatgaag ttgtagagtt
      121 ttgcaataga ataaaaggta aagtggaaag tgttgcaata agtggagtat ttgctccagt
      181 aaataaacaa caagaagaag aagttgcaaa atgggttaga gaaattttag gggatattcc
      241 tatatcttta tcaaatgaaa taggtaatat aggtatatta gaaagagaaa atggagctat
      301 tttaaattct gcattgtctc aagtaggtaa agctgtatct ttaggatttg aaaaagcact
      361 taaagactta ggtatagatg ctcaaatata tttcagtcaa aatgatggaa cattaatgaa
      421 tttagagtat acaatgaaat acccaatttt tacaattgga tgtggaataa caaattctat
      481 aagaggagct tccttcttat caaaagtaaa aaatgcaata gtattagatg ttggtggaac
      541 tacaagcgac ttgggtgtac tatataatgg attccctaga gaatcatcta ttccagttac
      601 aattggagga gtacatacaa actttagaat gccagatgtt ttaactattg gtcttgctgg
      661 tggtacatgt gtaaaaggcg aaaaagataa tataaagata ggtcctgaaa gtgtgggata
      721 tagaataact gaagatgcaa taatatttgg tggagacact ctaactttat cagatgttgt
      781 tacaaaatta gatatggcgt ttgaagatag aaaaagcaat gttgaaaact tagataaaga
      841 gtattgtaat gaggtatata agaaggttat tttaaaatta gaagatgctg tagaccaaat
      901 gaagactagt caagatgatg ttgaattggt tttaactggt ggaggaagta taattgttcc
      961 tgaaaaacta aaaggcataa gcaatgttat aagacctcct cattatactg ctgcaaatgc
     1021 tattggtgca gctttaggac aaataagtgg agatgtagaa aaagtataca gtttagataa
     1081 aatgtcgaga gaagatgcca tagaagatgc aaaaaaagag gctgtaaata aagctctaaa
     1141 agctggtgct aaagaagata ctatagaagt attaaatata gaagatgttc cacttgcata
     1201 ccttcctggt aatgcacttc ttataaaagt aaaagttgtt ggtgatttaa tttaaagaat
     1261 aaatataagt atttccagaa ttatataaat atttctggac tcatttttaa acttatttta
     1321 tcaataaaaa cagcataact tttgactata ttcttataag tttccgaaca gccgatatat
     1381 acctattttt tgaggtttat cggctgtttg ttatctttta tcgcattcca actatttttc
     1441 ttaccgtatt tgctgtacga attgtaatct tatcacttac atttgaactg gcagtctttg
     1501 accaccaatt tgtcttttta taatctttac gactaaaaga ccaaaagata gcatttttat
     1561 aatgatatac tttttcatac tcttctttag gatttccaac ctcatcataa aactcgtcat
     1621 aagataagtc aggaaacata aaaataagat tatcatatat ttctttgttg ttatctcccc
     1681 accaattagg agcattattt agtatatctt ttaactcttc ttgtgaaata ataaaaactg
     1741 gtatttccaa ttcaaactgt ttttttatca ttaatcttat tgtatttgag ataaccttgc
     1801 tgtcatctac atcacttaaa aagacaacat taccactatt aaggtatgta gaaacttctg
     1861 aataaccaag ttctacaaag cttgctttta attcagacat aattatcttg ttcttaccac
     1921 ttatattgat acctcttaat aatgcgatat aacttttcat ataataattt cacctctaaa
     1981 cattcacatt tttctatgta gtacaaactg gaatttgcat cttttataat tctttcaaaa
     2041 cttcttcata tgtaattttt ttaatataaa aaaatcggtg cttaatttgt accgattttt
     2101 gtttttctta gtaaagaact cgtttttttg cttctgctat agctctagca gcactttttg
     2161 cttgcattct tttttcttct tcttttttaa attcatttat tgtttcattt agattcttat
     2221 catgttcatt tttttcttta tcttcgtttt ctctgtatac taatatataa tctattattg
     2281 attcgtttat tatttgagat atacttttat tttcattaat tcctattctc ttaacttcct
     2341 taagtagagt ctcatcaata tgaaccgttg tttgctttgt attttttgcc accttaatca
     2401 cctcttaaaa aaaattctaa cattaaaatt ttttttagtc aataaatttt aatattaaaa
     2461 ttctttaaat gttttatttg attttctaaa attttctatt gtatttatca tcttattttt
     2521 tatattttca cctagtacag aagactttag tctaggattt tcgatatggt cataaattgg
     2581 ttctaaaaat tcgacttcga caggaacaga gttaatttta ccaataggtt ggtatccttc
     2641 ataagtatct tttgaatttt ttattactag tggaacaata gggcattttg ctttatatgc
     2701 tatctttaaa gctccacttc taaactccga aaccaatgaa tttggttctt taatccatgt
     2761 taaatctcct tctggaaaca ctgccatact ttgacctgta agtatatttt gagaggcttg
     2821 ggctatactc tttataccct cacgattgtt ttttctgttt acatatacac atcttagtaa
     2881 ttttgcccat tctttaaata taggtatatt tctccaaact ggttcatctg caattacaca
     2941 tccaattggt ctttctacac ttgctgttag tatgaagctg tcaagcatac tagaatgatt
     3001 tacaacaaat agaagtggtt cttttggcag tgtttcctta ccaattatat taagctctat
     3061 gttcactata tctaaagatt ttttagcttg tttttgcata aattcaaatt tttcctttaa
     3121 gctaaattta tcaggattct ttttaatttt aataagccta ggtatagaag atgtaaaacc
     3181 tataagttga tatgtagcaa attttaagta attattcata aaattatctc cttaaaataa
     3241 aattatttat tactgtaaag attttaacat aaaataaaat ttaagtctat tttaattcaa
     3301 ttttgtaaca tatattttaa atagacagag attgagattt tatatttcca attttagtaa
     3361 tcagatttta tcaataaatt actattctat taatttaatt aaataacctt taaatttaat
     3421 tataaaaact gttgcagaaa tttctacaac agtttaaaaa atttacctta caaaaactta
     3481 ttttataaca agagagtata ttataaggct agtacagccc attttttgca ctgagaaatt
     3541 cttttgccat catcaccttg ttctttgtca tatgcaaatt gattaagcat ttcacatgga
     3601 aatgtatcac atagaccaca atgtgtaagg tttttatctt cacaacaaga ttttacagga
     3661 cattgttcac cccaaaatgg tttctcaatc tctgtacaac ctttacaatt gactttttcc
     3721 ttgtatccac attcataaca taaaattcca catcttgatt ctatcatttt aagtcactcc
     3781 ttaaatataa attttatatg attgtatatc aaaatttata cttttcattg taaaaatcgg
     3841 acaaattttt tatataggtt gttggattaa caccacaaat agatttaaaa tcatttataa
     3901 aatgagattg gtcgtaataa ccaatatctt gtgctaaagt tgcaaatggt attttattat
     3961 tttgtatttc ttgtaataca aggtttatac gaagtaatct aaggtatgat ttaacactca
     4021 taccaagaga attattaaaa attctattta aatgtcgttc actataacaa ctaatttgtg
     4081 aaatgttttt aacagacata atagagtttt gttttctagc attttcaaga attggtatag
     4141 tcatatctac tatatttgat ttcaataagt atgataagaa taacatatct aattgttcta
     4201 ctaattcttc tatagtactt gttctttcaa aaatggaatt aacctctaag ctaaataatg
     4261 tgttaaaatc ttcaagtgaa atttttaaat ctgtagattc tctttgagaa agacctgtca
     4321 aataatatac tccacctggg cgaaactcaa cgaatactct aaaaagtaca ttttctatat
     4381 cattttttac aatagtagtt tttgttgtgg ctccccagaa tgcgctttct ataccttttt
     4441 tgtcaaattt aaatatcata catccactag catcaggtat taatgtaaga ttttctttaa
     4501 tacttgtatc tggaatagat attgtatagt gtgctatata ctgtcttaac aatttatgtg
     4561 gcaaaatata tgtatactgt ttgcaggtat ttaaaatgtt attgattatt ttattcataa
     4621 gtatatcctc ctgatatata aaaaataagt atactaattt attttttata taataaacca
     4681 gttttgtttt aattgaaata ttctaataag atattttgtt aaatttagat acaataattg
     4741 taaagtaaaa tctcaaaata tacaattatt ataaatcata gatatttatt aaataaatat
     4801 attaaagaag aaggaatata aaacaagatt agaaaataat agtgttactt tcataataaa
     4861 tacatataaa gatattttta agaataaaat ttattattaa ataaaaaata aaggagagtg
     4921 atttaatagt atggcatcaa aacaaacacc aagaaacaat ttagaaaagt ttttaagaat
     4981 aagagtatta tcacatacag gcgataaaat acatataaag ttacctgtaa attttgcaaa
     5041 gagaatgatt gagaataatg ccttggattt atttaatgga aaagatgatg tagtagatgg
     5101 taaaaaagtt actgaaatat tagttaaggc atttgactat gatttaactg gagaagtagt
     5161 tcacttggag agaaaaaatg gagacattat taaagtttca attgtacaat agaattattt
     5221 tatatgaatt ttatttttga atagttataa ataattagaa atttgtaaaa aagtataata
     5281 tattattagt aatggtacag aatacacatt tataatttat agatgtgtat tttttgttta
     5341 aaaaatttaa atatataaaa ctataaaggt tacaattttg gaaatagatg taaatatatg
     5401 ttgtattgta taataagagt aatataaaat ctagtaaaaa taatcaaata aatttagctt
     5461 atgagaggga taactatgga aaataaggat tttaaattaa caatatgtat atttgctttt
     5521 gtaattggag tagtagtatt attctgttgt ataggtttag gtgaatttag tgcagagcat
     5581 attattcaac aaaatggtgg aatcatggat actgaccaat ataatattta tctagaccaa
     5641 tctatttctc aatatagaaa ttttggttct atattagctc tgttaggagg aatagggata
     5701 ttgtttgata aatatatcag aaaatactag agattatgtt ttgtctaaaa taaattctta
     5761 tgaggagata aaaaatggca acagaaatat ttactgtaaa aattacaccc ttagaggcac
     5821 aaaaaatgat aaaagaaaat cttgatgcag atttagtttt tagtgattct tataatttag
     5881 gagatgataa atttatacta attacaactt ttgagaagta ttatgcaaga aataatagtg
     5941 atgcaggatt aatagtagtt tatgaaaata ccacaggaaa aacagttatt aaagctactt
     6001 caacaggcag tgcaattgga attttaaaaa ttgattgggg tgcaggtgga aatttactta
     6061 aaagagtaaa aaacatactt gctgattata ttatttaatt attttatcta actgataata
     6121 tgtcaagaaa atctcgtaaa agaggttaag aacattttta taatatatag ataaataaga
     6181 atttgaaggt aaagttttta aggtataaag aaaaataata taataaaacg aattggcttt
     6241 ataattcttt ataaggcaaa gagcacattt ctttatataa ttgttggata ttaaataata
     6301 tgtaaataca ccatttacat ataaaaattt aattaatatg ttaagagaaa atgaaatgga
     6361 aattactaaa aaatattttt aaattggata atggttgata ttatgtttat acaaaaatca
     6421 tgtggaattt tatatatttt aaatatgata gtttaaaatt atgaaagaat gataaattcc
     6481 agtttgtagg gtaattttga taaataata
//
LOCUS       DAGQVA010000124         6465 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.128, whole genome shotgun sequence.
ACCESSION   DAGQVA010000124 DAGQVA010000000
VERSION     DAGQVA010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6465
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.128"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            193..1596
                     /locus_tag="MIV85_003591"
     CDS             193..1596
                     /locus_tag="MIV85_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBY2962891.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1687..1927
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1970..2668
                     /locus_tag="MIV85_003592"
     CDS             1970..2668
                     /locus_tag="MIV85_003592"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBY2962892.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2691..3692
                     /gene="trpS"
                     /locus_tag="MIV85_003593"
     CDS             2691..3692
                     /gene="trpS"
                     /locus_tag="MIV85_003593"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBY2962893.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4344..5911)
                     /locus_tag="MIV85_003594"
                     /pseudo
     CDS             complement(4344..5911)
                     /locus_tag="MIV85_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(6247..6429)
                     /locus_tag="MIV85_003595"
     CDS             complement(6247..6429)
                     /locus_tag="MIV85_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962894.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
BASE COUNT         2288 a          772 c          998 g         2407 t
ORIGIN      
        1 attaaagtgg taaaactttt aaatttatca tttttaataa gatttgattt caaagtattt
       61 aaggtttatt attaaaactg tttttgaata tgcaaatatt ttgaaaaata tcagtttaat
      121 aataatgaat ctattttatt aattttgaaa ttaaatttaa aataattaat agagagggga
      181 aattaaatta ggatggaaaa gaaaaaaata ggcctatgga gtttggtatt tatgaatgta
      241 tcagctttat atggtataag atggatagct aaatctacag catcaagctt tggtttagga
      301 ttaggtgcaa tacctatgtg gttattattc tcatttatat actttgtacc aggagcttta
      361 atttgtgctg aattagcttc tacatatcaa aaaggtgatg gaggtcttta cgattgggtt
      421 aaggaagcct ttggagaaaa gtatggattt ttagtttctt ggttaaactg gacagctaaa
      481 atattttggt attcttcatt tttaactttc ttagcagtaa atgtttctta tacaatagga
      541 aatccagccc ttgctgataa taagatgttt gtacttatat tatctttaat aatattctgg
      601 gcattatctc ttatagcaac taaaggaata agttttacaa aaatatttac taatacaggt
      661 gcattaggtt caacaatacc aagtgctata cttataatat tttcatttgt agcagtattt
      721 gtgttgaaaa aacatgatat agcttctaca tacacaatag cttcaatgac tccaaaactt
      781 aatatggatg catttgttgc tatatcagct ataatgtttg gtttagcagg agcagagact
      841 gctgctaact tcataacaga aatagataag cctgaaaaga acttccctaa ggcaatatta
      901 atatcagctg gaatagtagc ttcattatat gtattaggtt caattgcaat aacaatgata
      961 ataccaccag accaaattac tgcttctaaa ggtgtattag atgcactttc tgctgtttgt
     1021 gcgtctttag gaattggttc ttggttggtt caattaatag cttttggtat agctttttca
     1081 gtattaggag caatagttct ttacatagca tcaccaataa aaatgttatt tggtagtgtt
     1141 aaaaaaggaa tatttccaga tagtttagta gaggtaaatg aacacaagat accttctaaa
     1201 gcagttatac ttcaagcaat aatagttact ataatactat tggtgactac attaatgcct
     1261 tctgttgatg ctatatacaa tgttcttgta actatgacag cattaactgc attattccca
     1321 tatgtattgt tatatgcttc ttatattaaa ctaagaaaag agagaccaga tgaaattaga
     1381 ccttatacta tggcaaaatc aacaagtact tgcctaggtt tagcaaaaat ggttttagtt
     1441 gtaactgtag tgggtatatt attatctgca gcaccagtta tgcctacatt tgctgaaaat
     1501 gttatatatg agatagagat gattggtgga ggtcttctag ttatattatc tggtctatgg
     1561 ttatggaata gatatgaaaa gaaaacagct aaataaaatg tattttaaaa atttcttttg
     1621 gatattataa tatatagttg acaatttata gtgtaaggaa tattataaaa taaagaaatt
     1681 aataaattaa atcctgagat aagaaatagt aaataaatat atttttgcac agagaattaa
     1741 ggatgctgag aacttaataa aaagtattta ttgaatgggt ctttgaggag taaaatgaaa
     1801 tgtaatttaa tattacagag tatttgatat cgtgtatgca cgttatagca tatattaaga
     1861 tatatatatt caattttgag tgtatataaa tttaggtggt accacggaaa atatatccgt
     1921 cctattgatt taggacggat tttttaatat agaaaattta ggaggaaaaa tgaacgtaat
     1981 aggaattata ggtgcaatgg atgaagaagt tagtatttta gttgatttaa tggatattag
     2041 agagactata aaaaaagcta gcttagaatt ttataaggga attttggaag gtaagaatgt
     2101 agtgttagta aagtgtggca taggtaaggt taactctgct ctttgtgccc agatactaat
     2161 aagcgaattt aaggttgatg ctattgttaa tacaggtgtt gcaggagctt taaacgaaaa
     2221 acttgatgtt aatgatatag taatatcaac tgatgctata cagtatgatg tagacactac
     2281 agcatttgga gaccctaagg gagttatacc aagaatgaag acttctgtat ttaaagcaga
     2341 tgaaagactt atagatgctg cttacaaatc ttctgtggaa gaagtaaaga ctcataaagt
     2401 attaaaagga agagtagtta caggagataa atttataaat tctaaagaat taaaagaaga
     2461 attagtaaat gattttggtg gatattgtgg agaaatggaa ggtggagcta tagctcatgt
     2521 atgctattta aataatactc catttgtaat aataagagca atgtctgata aggcagatgg
     2581 aagtgctgat gttacttatg atgtatttgt acatgatgct gccaataact ctaaagacat
     2641 agttttaaat atgttaaaat caatataaat atataaggag gtacaaaaaa atgagtgaaa
     2701 aaaaagttat atttagtggt gcacagccat caggcaaaat gactttagga aattatttag
     2761 gagctataaa aaactggact gaacttcaag acaattatga ttgttattat agtatagttg
     2821 atttgcatgc aataacagta cctcaagacc ctaaagtttt aagagccaat actatagaat
     2881 tacttgctca atatatagct tgtggattag acccagaaaa aaatactata tttatacaat
     2941 cacatgtcaa agagcatgtt gaacttatgt gggtattgaa tactatgact tatatgggtg
     3001 aattaagtag aatgactcaa ttcaaagata aatcacaaaa gagtgaagca aatctaaatg
     3061 caggtttatt cacatatcca gttcttatgg ctgctgacat attgttgtat caaactgacc
     3121 tagttccagt tggagatgac caaaaacaac atttagaatt agctcgtgat ttagcaaata
     3181 gatttaataa tagattttca cctacttttg tagttccaga aggatactac ccaaaaggtg
     3241 gagcaagagt gatgagtttg caagagccaa ctaaaaaaat gagtaaatcc gattcaaatg
     3301 aaaatgcatt tatactatta gcagatgatt cagattctat aaagagaaag ataaaaagaa
     3361 gtgttactga ttctttaggt gttgtaaaat acaatgatga acaaccaggt attaaaaatc
     3421 taattgatat atattctaat ttaagtaaaa agagtgtaga agagattgta aacatgtatg
     3481 aaggaaaggg ttatggcata tttaaagaag atgtggctga agtagtatca gaagctttaa
     3541 gacctataag agaaaaatat gttgaccttc ttaataataa agattattta gaaaaaatat
     3601 atagtatggg agcagaaaaa gccgaaaaac aagctagaaa aactcttaga aaagtttata
     3661 aaaaagttgg atttatagag agaagatact aattattagc tatctttact tgataaataa
     3721 attttaaagt tattaaaaag gtatatgata tgaaagagag agtctcaaag tgaacttttg
     3781 ttcatgaggc actctttttt gtatgaaata aaatatattt taatcatttc aacaatgaaa
     3841 aagaggatta tctctatttt gagacagcat cttttgataa taaaaaaaga tgagcttttg
     3901 ctcatctcaa aggggttaga ttattcttac tttggggaaa gtagaataaa ggtaaaagtt
     3961 aactgatgtc aactttgtct tttttgcata tcactactga gcataaaaaa atcagaaaac
     4021 catagccttc tgaaacaact tctaacatac attgtatttt atacccaata tgtaatttat
     4081 gagttaattt taactcttat aatgaaaatt gtcaataata tatcaaaaaa atatttttta
     4141 aatttatata attaaatgaa tttatgttta tatataggtg atatgataca gataattatc
     4201 tttttaatac aatatagttc taaaaaagaa tatattagaa gaagataata tttaaataaa
     4261 aaatacctta taaagttaat tttttaatac tttataaggt aaatacatat tgtattgtgg
     4321 ggataaattt aaatcatttg atactaatca acactaagaa ccaataactc tctatcatct
     4381 tgagtaattg tatatattct taatttcttg tatgtcataa tattttctcc acctgtaaaa
     4441 taactcctaa gattaacaca atcagtttta ggttgatttg tatctcctaa ataattacgc
     4501 aattctttat ctttagtttc aatatcttta aatccaaaat attgtaaagt agcttcaact
     4561 ctatattttt ggacataatc gagagcttct ttattagttt atgttggtgt aaaatacata
     4621 ccatttatat aagcctttat tgtacttgga ttaaatttaa aatctgcaga atatatttta
     4681 tgtgtaacta ttatttcttg aacagttgga attttaactt ctggttcatc aagtatttca
     4741 ggagtactat ttagctctgt aatagataag ttatctaagt atattgtatc actatcaatt
     4801 aatgctatat ttatattaga agaatctttt tcagtagttt caaattcata actaaatttt
     4861 gtatatcctt gttctagtac caaataatcc gttttttctt cttttacttt tatatttaca
     4921 attattgaat tatatgttaa aggatttttt gaattttact aaaaacataa cgtttataag
     4981 gttttagttc agacataggt attttaatct tcgtctcacc atttaatcta tttgctgagc
     5041 cttttaaacc atcttgattt gtagtattaa cattactcca tatactaggg taattattgt
     5101 aatcatcaaa attagtaaag taagttggtg tttttataag tatattcatt cctctttcaa
     5161 gtttaacatt acatatttgt ttatcagaca aagtttttaa actgtcttta atcttattgc
     5221 ctatattatc atcaaatatg agttcaacac aactttcatc tattggtata ttattaaaat
     5281 ataacaaacc atctttttta gtagtgccaa aagttttttc aattgcttct ccaattgtaa
     5341 gttcaggtgt tttatcttct gggacctgta aacttttagc agtaattctt cttttgtaag
     5401 attcattttc tgtatctaat ataatagata cagaaatact gtcaatttga cctatatcgt
     5461 cttaccaact atttcattct gttactattt gtccagaacc attttttgta ccaaaatttc
     5521 cacttacttg tgttgtttct aatttaattt gctttccatc atctaatttt tttaattaat
     5581 tataatttat aggaatcagt ctagaactaa attgatacat tgtgttaaga gccataggtg
     5641 aaaatccttt tttgagataa gtatttccag gagatagatt attgccaatt tgattttctt
     5701 gtgctttgat agttgataat gcatctccat ctaacactaa atttgttgtt ggtgtcactt
     5761 tgtacatagg tgcagtacct gtgttgtagt atctaatatt tgcatttata tatgcagatt
     5821 ctcctttgtt tatacttaat ccagtatttc atgattatcc attgctattt tgaacagcag
     5881 ttgaattatc tgttgtatgg taataatttg tcttgtatag tttctttaaa ctcattaaat
     5941 ttttctaatg aaatttcgtt ttgatttttt gttcttatta ctttattaaa tgcaaatttt
     6001 tctggagatt caaaataata tacatacata ggtttatcta ttttattttt tgatatagca
     6061 tttcgaagtt ctctatattc tttttctcaa gaatttgctt ctatttgata atcataaaaa
     6121 taatttcttg tctgagaata tttgcttatc tctatagaat cttttttata tgatcctaat
     6181 acttcttttt cagatttttc aagtttttga tcttttcttt ctcattcttt agccttttct
     6241 ttatctttaa aaaaatcctt ctgatctttc tataggagcc ttgtaagtag tattacaaac
     6301 ttttccacta tagctttgta aatcttgtgc ataaatgtta ttaggtaaca aactacctaa
     6361 agttagatat aatatcaaca atatagatat acaattacta atacttttat gtttcctaaa
     6421 ttttttcatt tattctccct acaaatatta gtttagttaa ctttt
//
LOCUS       DAGQVA010000125         6378 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.129, whole genome shotgun sequence.
ACCESSION   DAGQVA010000125 DAGQVA010000000
VERSION     DAGQVA010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6378
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.129"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..1010)
                     /locus_tag="MIV85_003596"
     CDS             complement(<1..1010)
                     /locus_tag="MIV85_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBY2962895.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINVCISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FD"
     gene            complement(1158..1949)
                     /locus_tag="MIV85_003597"
     CDS             complement(1158..1949)
                     /locus_tag="MIV85_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBY2962896.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(1985..2641)
                     /locus_tag="MIV85_003598"
     CDS             complement(1985..2641)
                     /locus_tag="MIV85_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962897.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(2634..3599)
                     /locus_tag="MIV85_003599"
     CDS             complement(2634..3599)
                     /locus_tag="MIV85_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBY2962898.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKNLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISNKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(3705..3811)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4101..5045)
                     /locus_tag="MIV85_003600"
     CDS             complement(4101..5045)
                     /locus_tag="MIV85_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBY2962899.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSASIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATVIEPIELKHLIKSKVLELYNHHCI"
     gene            5156..5623
                     /locus_tag="MIV85_003601"
     CDS             5156..5623
                     /locus_tag="MIV85_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962900.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(5793..>6378)
                     /locus_tag="MIV85_003602"
     CDS             complement(5793..>6378)
                     /locus_tag="MIV85_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962901.1"
                     /translation="TLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNNEGYMN
                     YYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRDKIQSF
                     VTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQNDFIKL
                     VHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2095 a         1055 c          670 g         2558 t
ORIGIN      
        1 ttatcaaatt tcttcaattt ttcagcaact ttttcatctt cctttataaa agttaatatt
       61 ttataataat tattcatatc ctttgaaaat tcatctttaa atttattatt tgtgtaactt
      121 atattaaaat catagtctgt tactatccat acatttggta ttgtatccag agcttgtcta
      181 agtaattctt ttctctggtc tatgtagttt tttaatgttc tttgtataat catatccttt
      241 tctattgcta aatttatctt tcctaattgc tctgactttt tacttaattt tttattgatt
      301 gaatcaagtt cataatatgg atacactact ctattattaa gactgtatac atatacataa
      361 taagtatggt tacataatag taaatatatt actcctatta atctatctga atctactata
      421 ttaatcttag aaattgctac aaaacatata atagttgtaa aaaaaacaaa atatgttaaa
      481 tcttttatta acttatagtg ctcaatgtta ctatcaagtt tattcaacaa atatagtaaa
      541 ttaaacatag atatacaaac attaattaat ataataatca tattccagtt aatatcacta
      601 aaaatatttc ttataaagta atctaatatc acaaaagcac tataaaaaat tagtattggg
      661 cttattctta gtttttttac tttagaaatg gttaagtata taaaagtaga catattaatt
      721 atgcttaagt taagcaatac aatttggaat ttttgaattt ttaaatttac tactcctaaa
      781 atacttacaa aaactaatac aagacaccct actttcaata tatttataaa ttcatctgtt
      841 ttaaagctac ttatataaac tatagaatat ccaaatatcc aaagtaaaat tattctatac
      901 atatttatag aaactgtata caaatttata tttaaaagtg caataaccaa aaataaccca
      961 ttagctagta tatagacctt attcttactt aaagttcctt tagattccat attccccacc
     1021 acttcttcat ttttatatag ttttacctat aaatatgtta ccacaattct tccaaaaaat
     1081 ttgtcacttt ctagttataa aaaaaaatga gtaaatattt ttaattttac tcattttgta
     1141 gattttgtat attcagttta aaaagctgga actatacttc ctttatattc atcttgtata
     1201 aattttttaa cttctttact attcatagcc tctgataaag ccttaatctt atcactatct
     1261 ttattatttt ctctacaagc tattatattt acatatggag aatcacttga ttctattact
     1321 attgcatcct tagtaggatt taagttagct gttaaagcat aattagaatt tattactgct
     1381 ccgtcaacat cttttaatac tgttggtaat tgctctgcat tcatttcttt tattactata
     1441 tttttaggat ttttagttat atctttttta gttataagct ctccatcttt tacttctatc
     1501 aatttatttt ttgctaataa tttaagtgct ctagctccat tagttgcatc atttggcaca
     1561 gctataacag ctccatcttt taattcatct aatgacttaa ctttttctga atagaatccc
     1621 attggctcta tatgaacttt agatgtataa gtaagtttat atcctttctc cttcacagtt
     1681 tcctctaaaa atggaatatg ttgaaagaag ttagcatcca aagacccttc atctaaagct
     1741 gtatttggaa gtacataatc atcaaatatt tttacttcta aatcatatcc tttttctttt
     1801 aacaaaggtt ttgcaacttc caatatcttt gcatgtggat ttgatgaagc tcctactagt
     1861 atttttttat cctctttgtt tgaacaacct actgctgata ttgctattgc tgacaccaat
     1921 gctactgata ataatttctt taatttcatt tttactcccc ctctttaaaa tgtttataat
     1981 taatttattt tagtttctta taagccagat ttcctactcc ctggattatc tgaactaata
     2041 ttataagtgc tattacagta tataccatta ctgctgtatc aaatctttga tatccataaa
     2101 taagtgctat attacctaat cctccagctc ctactgcacc tgccatagct gtataaccaa
     2161 gtatagatat tattgataat gtaattccag atactattga aggcatagct tcctttatca
     2221 taactttaaa tactatttgt ctttttgtag ctccaaaaga ttttgctgct tctatcaatc
     2281 ctttatcaac ttcatttaat gagctttcta taattctagc gataaacggt gctgccccaa
     2341 tagttattgg cactattgca gcagtttccc ctatacttgt tccaacgatt aatctagtta
     2401 ttggaatcat tgcaactata agtatcataa atgggaaact tctaaatata tttactataa
     2461 atcctaatgc actatttatt gtgctatttg gttttaatcc atctggtttt gtaactacta
     2521 atatgattgc taatataaat cctaatattg ttgccactat agttggtact ataaccatat
     2581 acaaagtttg taacaatgca tttggaaata gtgttgttaa aaagtcaatt aaactattca
     2641 tttatcattt cctcccatct tatgccctta ctagttagat attgttttac ttgctctcca
     2701 cttttatttg aaatgtttat aataagtgaa cctaaaatat catctttaaa ttgttctaat
     2761 ttcccaaata ttatagacac atctatattt agttctcttg ccatagtcgt aataatagct
     2821 tcattagaaa tatctttagg gaatagtatc tttatatttg ttccttttgg caatattata
     2881 ctttcttcac ctattaattt tctaagtcct ttagtatttc ttaagaatat ttcttctgta
     2941 tctcctacct ctaatacttc tccattttcc attattgcta ctcttccaca aatctgcttt
     3001 ataacttcca tttgatgagt tacaactatt attgttattc ccaagttttt atttatatct
     3061 tcaagcaatg aaagaattga ctttgtagta tttgggtcta atgctgaagt tgcttcatca
     3121 caaagaagta cttgtggatt tagtgctaaa gctctagcaa ttgcaaccct ttgtttttgt
     3181 ccgccactta gatttctggg tttatcattt ttcttttcag atattccaac tacttctaat
     3241 aactctaaaa ctcttttttt aatttctgcc tttgagtatc caaaacattc taatggcaat
     3301 gctacattat caaatacagt ttttctttca agcaatgaaa agtgttgaaa aatcattcct
     3361 aactcttttc ttaaatctct catttgcttt tcattcaatg actttacttc tttatcagaa
     3421 acaagtacac tgccttcttg gtattcttct aatccgttta tacatctcag tagtgttgat
     3481 ttccctgcac cactatgacc tattattcca aaaatttctc cagattctat ttcaatactt
     3541 acatctttaa gcacttgaat ctttccataa tacttattaa cattttttat gctaatcata
     3601 aaatttcctc ccatatattc tgctcagttt ttatgtttat cctctcttat gtattacaac
     3661 aaaataaaag cccgagtata aactcaggct tagaaagcta tttatactca tctatcaact
     3721 atattagttg caggatttag caccaatgta tataaaatat actggttgcc gggtttcaaa
     3781 gggccagtcc ctccaccact cttgataaga cgttatttaa tttaattcta ttatcatttg
     3841 ttgctatgtt atatatgata tattcattaa tagtatttgt caataaattt atttaaattt
     3901 tttatttttt attatcgtta attaactatt tttaattagt tttctagctc ctaacacttt
     3961 atattttaat gtctatataa ctatagaaca tcattataag aaataaatta aataacatca
     4021 atctatctaa atcatctgta aagtaaatta agaaaattaa cattttatcc aaactctatc
     4081 ctactattaa ataaaataat ttaaatacaa tgatgattat atagctctag tactttagac
     4141 tttatcaaat gtttaagttc tataggttct attactgtag catttttccc aaaagttaaa
     4201 aaatattcag ccacccagtt aagtgtagat tttggtatat acatatctat gtatccacct
     4261 ttagacaaga ttttcaaccc tcttgccaac aaaaattctg tttcacaacg ttttactccc
     4321 tcatctgtca aattaatttt aatatgataa tctgtaccta cttccatatt cttaagataa
     4381 tcatgtatag aagataaaac cttatatttc ttacttgata agttttctat actcaaaatc
     4441 ttcacaattc tgtctacacg aaattcctta atagatgctg attttataca gtaagctgga
     4501 caataccaaa gtccattcat ggcatacaaa ccaataggaa caatggtacg tacactattt
     4561 ttttgctttg atgaatattc aattttaatt gtaaattcat tcattactat attaaacaat
     4621 tctttcaata atggtgttga acagtgccta tctggtgtcc aaaaaacaaa tttacgcctt
     4681 atattctcaa tattatattg aatatcattt ggtatacaat ttaaaaattt ttttaaaaca
     4741 gaaatagttt cttgctcaaa tggcaaatca ttataatatt ctagtgactg atatgcaaag
     4801 aatatagatt ttacctcact ttctgaaaat gcaatcggtg gaagtatacg ctctttaagt
     4861 acatgatatc caccagccgc tccaactttt gaatataatg gaaatccaat actctccagc
     4921 acctgtaagt ctcttagtat agtacgtttt gatacagaaa attcttctgc taattctcct
     4981 gctgtaaaac ttctttttgc atttattgtt atcatcagtt caattaaacg ctcagctctt
     5041 gacatattta tactcctaat ttaaatatag tgacaataat tgtcactatt atatgataag
     5101 atattcttac atttaaagca ataataatag taaagaaaga agggactgat actttatgga
     5161 aaataatact attaaggctg atgatattat caattattgt ctatcaaact tagatgatgt
     5221 tttattaatg aatagttggg gggaacgagc aatttactac aatcctaatg gtattttaaa
     5281 gcgaggagta tatgttctta ccattaaaga aaaagacagt aatcatgata aaggttcgtt
     5341 ggttagtcgc ccaaatgtat accgtgtgaa tataggatta aaaaaagaaa cttttattga
     5401 aatgtttgga tatattccaa agcgtccagg tgtaggtcaa atagttgata tggattttga
     5461 ttttacaaaa ttggacacaa tcatgccaca tcctatctac tcatggatgg gatggatatg
     5521 cgtcctaagc cctactgaaa agacatttga gaactttaaa actttaatag gagaatctta
     5581 caattttgca aaacaaaaat ttaaaaagag aaaaaacaag taaaaacgta tgaaaataat
     5641 ccctaaataa attataataa aaatattaag gttacaagat aaaaattaat atcttaataa
     5701 catgcaaaaa agcgaagcca aaaaatgtat tatttataag gcttcgctat atctcaaata
     5761 atttatttca aatttcaaaa ctatttattc tattatttct tattatttcc tgttattcct
     5821 aatctatcat tcatatcttt tatcattttt ctaaaaccac tacctatatc atttccaaca
     5881 tcttcagttc catgaactaa ttttataaag tcattttgac cttttttcat atcttcatca
     5941 gataccttat ctaatttttc tattctctta tctatgtctt ttactaatct ttccccttca
     6001 gcgattaggt catcattcat tttctttaac tctgtatctt ctgttttacc atctttttta
     6061 agagatgtta caaatgattg tattttatct ctactatctt tatatgcagc ctttacatca
     6121 cttagatatt tttcatttcc tggatattct ttatctttaa actgattatt tatactttct
     6181 ggagtatcat aaatagaata tctatttaga cctgctatat aatcattata gcttgttgaa
     6241 taataattca tatatccttc attattattt acagattcat taggattttt tcctgtattt
     6301 tcacttggtt tttcattatt tttagtacat gcagttatac ctatagctaa tactagtgct
     6361 aatcctacaa ataaagtt
//
LOCUS       DAGQVA010000126         6344 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.130, whole genome shotgun sequence.
ACCESSION   DAGQVA010000126 DAGQVA010000000
VERSION     DAGQVA010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6344
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.130"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            357..1631
                     /locus_tag="MIV85_003603"
     CDS             357..1631
                     /locus_tag="MIV85_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBY2962902.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1838..2155)
                     /gene="trxA"
                     /locus_tag="MIV85_003604"
     CDS             complement(1838..2155)
                     /gene="trxA"
                     /locus_tag="MIV85_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBY2962903.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2422..3174
                     /locus_tag="MIV85_003605"
     CDS             2422..3174
                     /locus_tag="MIV85_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBY2962904.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3161..4042
                     /locus_tag="MIV85_003606"
     CDS             3161..4042
                     /locus_tag="MIV85_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBY2962905.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTILSGEIMY"
     gene            complement(4268..5623)
                     /locus_tag="MIV85_003607"
     CDS             complement(4268..5623)
                     /locus_tag="MIV85_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBY2962906.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2432 a          922 c          810 g         2180 t
ORIGIN      
        1 tctaatcaat ttctttacta tttttacaac tttattagtc atattcataa ttatttctaa
       61 ttagtgttta acattttatg taaaatttat aaaaaaatgt atataaatta aaataagtga
      121 ctatactaaa aatatgatac ggataaacaa taagttcaac ctatctcccc caaaatcaag
      181 tgagctacag tttcccccaa ctgtagctca ttttcgtgta atttaataaa catctcaaca
      241 agaattaatt aacaaaaccc cttataaaaa cataacatat attaaacaag ctcttgatta
      301 aaacttgagc ttttttaata aaaaacagaa tagtttatta gataaggggt ttttttatgc
      361 aattcatgga tgtatctaaa tacattgaag gtgcaaacct taaagttaaa actaaaaatg
      421 gtgaaactgt taaaagaata tattttaaca actctgccac tccattagtt ttaaaaaacg
      481 tagtggataa cttaaactgt gagattcctt ggcttactta tattaatgct ccaggaataa
      541 tctcagaaaa aaatacttta aaatatgaaa atgtacgctc tactatcctc aaacttattg
      601 atggagacga agaaaaggat tctgttattt atgtcaaaaa tgctacagaa ggaataaact
      661 tcttagcaaa attttttaaa gatgaaaatc cagataaatt tgttattacc acagcaatgg
      721 agcatatggc taattacctg ccttttaaag ttaattttcc tacaaaagtt gttggaatta
      781 cagaaaaagg agaacttgat ttatgtcaat tagagaatat acttaaaaat tatgctggta
      841 atgtatctct cgttacagtt acaggagcta gtaatgtcac aggtataacc actcctatat
      901 atgaaatagc aagaatagct cataagtatg gtgcaaagat attggtggat attgtgcaag
      961 taattcagca taaacctttt tcaatgatgc cacatgaatg tgatgagcat atagattttg
     1021 ttgtttttag tgctcataaa tgttattctc cactaaatgg aggagctctg gtaggaccta
     1081 aaaaattctt tgaaaaattt aatcctgtac tatatggctc aggttctacc aaatttgtaa
     1141 atgataacaa aatactatat gcaaacgtac cccaacgttt tgaagcagga tacccagagt
     1201 attttggaac tcttgcaatg ggaaaagcac tgaacacttt aaataaaatt ggtctaaaca
     1261 gaatttcaaa atacgaaaga gaattatttt tatatgctaa agaagaaatg agtaaaatac
     1321 ctaatataat aatatatgga gataaatcaa ataatgtaat tatcccaaat atatctttta
     1381 atataagtaa tatgtattac aaagatgtag caaaatattt agttgataac tttggaatag
     1441 aaactggagc tggagtagta ggtgcagata tttatgtaca aaaattatta ggtataaatc
     1501 caaaagaggc atacgtcaga tttatgaggg aaaatcctgt aggtcttgtt aggataagct
     1561 taggaatgta caatactttt gatgaggtgg atagctttat acatgctatt aaaactttgg
     1621 cttttaaata agatttttct attctttttt atcaataaat agagagtagt tttgttttca
     1681 caaaaaaaca aattatatca acagtcaatt tcattagcaa ttagacactc atttgtaact
     1741 atacaaacta ttttacacta tacaaacaaa aaactcatta caatgagttt ttttgtttat
     1801 atatgagatt tattttaatt acttcaattt actttaatta catatatgat tcaattttgt
     1861 tttttaaatt ctccttaggc ataaaaccta ttaatctatc tacaggtttt ccatccttaa
     1921 atattagcat agttggtact gtagatactt caaatttctg agctaattct atactttggt
     1981 ctatgtccac cttcaagaag tttgcttttt caaccatctc atttcctaaa gcttcatata
     2041 ttggtgatag catcttacaa ggtccacacc aagtcgcaaa gaaatctaca actactaaac
     2101 catctttatt ttctacttca tttataaatt cattattatt tattattttt accataatat
     2161 acatctcctt tattatcttc ttgatattaa tatactacgc cctatataac agttcaatta
     2221 ggcacttttt tgtaaccgcc tatttttaat agatttaata ttatgataaa tagatttata
     2281 agattaaata tttatgagac taaatatttc taatatattt tatttttttc ttaatatagt
     2341 tgacattttt tcccttaaat tataaaatca aattaataac tacataggta gttactaatc
     2401 ttttatcaaa ggagtttcta tatggataat ataattaatg aattacaaaa tataggattt
     2461 actaaatacg aatctcaaat atacatatca ttattaaagg aaagcccttt aacaggatat
     2521 gaaataagta aattatcagg tgtaccacaa tcaaaagtct atgaaaatat aacaaagcta
     2581 ttaaacaata atataattat caatgttgga actgacccta ttaagtacat accaataaac
     2641 cctaatgaat tattaaaaaa taagaaaaaa gaatttgaca attctatgga taatctaaag
     2701 aatagcttac agatattaaa taaaagtaaa agtgtagaat acgtattaaa cataaaagga
     2761 gataaaaata tattaaaaaa agcaatagaa atgataaaaa atgcaaaaca agaaattata
     2821 atttcttgcc cttatgaaga aattcttgaa ttaaaaaaag aactcctaat tgcttacaaa
     2881 aaaaatatta atattgaaat actactttta gaaaacaaaa gtctgaaagg tcttgataat
     2941 attcatattc atggaggtaa taaaactaca cttgaaaata aaatgcttta caaaggaatt
     3001 attttgattg tagataatga tgaaatattg acaggaaact tatcagaagg cagtgaggcc
     3061 atttcaattt ggacaaaaaa ctctaacatt ttatatattg gagttcaata cataaaacat
     3121 gaaatttata tttcagaaca aataaaagga ggttataaaa atgaacaaaa ttaagattaa
     3181 acaagttgat gcttttacaa ctataccttt tggtggaaat cctgctggtg tcgttactga
     3241 tgcctctaac atttctgatg aaattaagca gaatgtggct aaagaaatga atttatcaga
     3301 aactgcattt gtttcagagt caaatattgc agattttaaa gtacaatttt tcacaccagg
     3361 tttagaagtt gatttatgtg gtcatgcaac aataggtact ttccatgcac ttttggaaga
     3421 agggaagctt aatactaata agagtatatt ttatcaagaa acaaaagctg gtgtattatc
     3481 tgtagagctt aagaaaataa ataatgaaaa tatatttatg atggaacaga atacacctga
     3541 atttgaaaat ttagataatt gcagaaaaga acttgcacaa atgataggtg tgcatgaaga
     3601 tagacttctt gaatatccta ttataaaggt aaatactgga ctttggtggc ttgtatttgg
     3661 tctaaaatct ttagatgatt taaaaaatat ctctccagat ttaaataaaa tcaaaaaatt
     3721 tagtggtgat aataatataa ttggtataac tccattttgt atagaaacta tagataaaaa
     3781 gtgtgactac catttaagat ctatagcacc atatgttgga gttacagaag accctgtatg
     3841 tggaactggg aacgcttgcg tatcatctta tatagtacat cacaatattt tagataaaac
     3901 tagttttatt ggtgagcaag gtaactttat aaacagacct ggaaaggtat atgtaaatat
     3961 aactagagaa aacaatgaca taacttctgt aaaaattgga ggaagtgctt atactatttt
     4021 aagtggtgaa attatgtatt aatcccatac ctaataaaaa caaataaaaa tactagctaa
     4081 ctaaagctag tatttttatt tgttattttt atttaataat catactctaa caaatattat
     4141 aattatatat atcataatat tgtatttaga agtaaaattt tatttttatt attaattagt
     4201 tataaatcaa tctaatacaa cataattaca gtagattaac ctataaaaca taataattgc
     4261 ttactaatta tttatcatcc tcaacaagtc tacttaatgt cttatcagat aagaataata
     4321 atatcgctgc aacaaatagt attactggaa ttatagtata tactttaatc atatcaaatt
     4381 taagagtaaa tgcatatata tatccgtatc ctttaccagc tataaaagta gcaaatgtcc
     4441 atactcccat aagaacacct agaagcttct taggtgcata cttacttaca aaagagttac
     4501 caagtggtga gaataacatt tcaccaagac ttaaaagaat accaaacatg attatccata
     4561 gtatactagc tttagcagtt tcaggagctc caacccctct tgaaaattct gcaccaacaa
     4621 gcattaagaa tgcaagacct aagaatatta atccaagacc tgtcttttta aataaactca
     4681 tatctccttg tggtctacta gcaagtttaa accataatgc tccaagaact ggtcctaata
     4741 ctatacatac aagtgaattt aatgagtcaa accaagcaag aggaacatca aatcctccaa
     4801 cattcatgtt tacaaatgct gcaccataat cataaactgc aagataagtt agataccaga
     4861 atacccagaa aattacagag aagaatgata taagtataat agcccaaatt ctcttcttat
     4921 ccatgcttgt aagaggagac ttatcttttt cttcaatttt ttcagcaact acaccttctt
     4981 taaaaggtct ctttcctgca ttcccaagga atctccatcc atatatgaac catattgcac
     5041 ctattacaca aagtacagct gctataaaga aacattgaga aaatccaagt acaccatttt
     5101 ttgcaaatgt tttaaggtaa agaataccaa ctgctatagt accaataaaa gaacctatat
     5161 taacaaaaga atactgtact gaaaatgctg tatcaagttc ttcttgacta tcaaaaagct
     5221 gtccatttac cgcagatacg ttacctttaa agaatgcagt accaattgaa actaagatta
     5281 tcattgcatt taccatagaa actgtagttg caatagaacc aagatagtat cctactccca
     5341 tgataagcat acctataggt atagtatatc tagctcctat ccatctatct gatatatatc
     5401 ccccaattat aggtgcaagg tatgtgaatg caacaaggtt ggcttgcatt atagcagctt
     5461 gtcctttatc tattccaaga ccaccatgaa ctatagctgt tgtaaggaat atatatatta
     5521 agtactttga agcataatat gctgctcttt caaatgagaa agttgttgag cagatataaa
     5581 atcccatagg aaatttaccc ttctttttta ctgttgagct cataatttta aatcctttct
     5641 taattgtatt tttatttttt acgttttgtc caaattcttt cttttatgaa agatataata
     5701 ttattatttt gtaaaacaat ttgtaattat tattaagata attgcgcatt tatttgtaga
     5761 gtacatattc tcatggaata aaattaatac acttcttaat cataaattta aattatataa
     5821 attcactatt ttcagatata gttataaatt aatatattct catctaatac catgaaaaaa
     5881 ccttcgccat atgcaattct tattttttac gtgatagtat tttacaaact aaaatccccc
     5941 ttttgtagca acttatgtaa ttacatttta gtgctttttt aaaggagtct cgaataaagc
     6001 aacatatatt ttgttcaaat aatgttttta tttatttttt aaatttatat attacttcac
     6061 tcaaccaatt ctcaacttaa ataactaaac tactatctat tcacagatta ggcttatttc
     6121 ttacacatta gtttataata aacactgtga atctaaacat aaaaactgtt attttaaagt
     6181 aattacccat atattcgctt tgatactatt tattgaggtt atactcttta tgtataatat
     6241 attatttata aaatacctca aaatatatta ttcataaaat acctcaaact gaaaactttt
     6301 tcacgaatat ttatttttca cctccccttt tttatttcac catg
//
LOCUS       DAGQVA010000127         6145 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.131, whole genome shotgun sequence.
ACCESSION   DAGQVA010000127 DAGQVA010000000
VERSION     DAGQVA010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6145
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.131"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..623
                     /locus_tag="MIV85_003608"
     CDS             <1..623
                     /locus_tag="MIV85_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962907.1"
                     /translation="LIYTHNNMFELGYKDIQLKEISLSGIEISVSNVLSCVEEAIDIS
                     NNEDEFREYFLGNNMIECIKKIKDTSYSSLEELSLKVENNTIYDRGDFFEFDIESNVR
                     EKEFLKAIKVRVKIKNPWIGIDIEDYMDKSNNNKIDDKTFNNYKASENNEIINQFKNE
                     SENIRNQEVVEFTEEDEEELKQNIIENIKKNFDEKNLVQVYKYRGV"
     gene            643..1062
                     /locus_tag="MIV85_003609"
     CDS             643..1062
                     /locus_tag="MIV85_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962908.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEVYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            1052..1576
                     /locus_tag="MIV85_003610"
     CDS             1052..1576
                     /locus_tag="MIV85_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962909.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKCSQKYE
                     TDFKIKVWNFSESI"
     gene            1888..2445
                     /gene="efp"
                     /locus_tag="MIV85_003611"
     CDS             1888..2445
                     /gene="efp"
                     /locus_tag="MIV85_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBY2962910.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            2537..2992
                     /locus_tag="MIV85_003612"
     CDS             2537..2992
                     /locus_tag="MIV85_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBY2962911.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            3155..3865
                     /locus_tag="MIV85_003613"
     CDS             3155..3865
                     /locus_tag="MIV85_003613"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBY2962912.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            3919..4989
                     /locus_tag="MIV85_003614"
     CDS             3919..4989
                     /locus_tag="MIV85_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962913.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            5017..>6145
                     /locus_tag="MIV85_003615"
     CDS             5017..>6145
                     /locus_tag="MIV85_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2962914.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLES"
BASE COUNT         2671 a          525 c         1131 g         1818 t
ORIGIN      
        1 gtttaattta tacacataat aatatgtttg agttaggata caaagacatt caactaaaag
       61 aaatttcttt aagtggaata gaaatatcag taagtaatgt actttcttgt gttgaggaag
      121 ctattgatat atctaataat gaagacgaat ttagagaata tttcttagga aataatatga
      181 ttgaatgtat aaaaaaaata aaagatacat cttatagtag tttagaagaa ctttctttaa
      241 aagtagaaaa taatactatt tatgacagag gagatttttt tgaatttgat atagaaagta
      301 atgttagaga aaaagaattt ttaaaagcaa taaaagtaag agtgaaaatc aaaaatccat
      361 ggataggaat tgatattgaa gattatatgg ataaatctaa taacaataaa attgatgaca
      421 aaacattcaa taattataaa gcatctgaaa ataatgaaat tataaatcaa tttaaaaatg
      481 aaagtgaaaa tataaggaat caagaggttg ttgaatttac agaagaagat gaagaagaac
      541 ttaaacaaaa cataattgaa aatataaaga agaattttga tgaaaaaaac ctagtacagg
      601 tatataagta taggggtgta taactttgaa aaaagaagga atgtgactgt aatagaatta
      661 atagtatcta tcagtataat actcttgata gttacattat cttttccaaa agataatctt
      721 gaaaatcata aaataaattt atttgcacgt caactttgtt cagatataag gtatgttagg
      781 cgaattaata tgtttagcaa ctacaataca tatatatatt atataaatca aggtaaacac
      841 gaaggttatg tattgagaaa agatggtaaa aacattaaat caataatgct acctaaaaat
      901 gcaaaaatag ctaggagtat tgaaataata aagtttaaat ctgatgggtc gcctcaaaag
      961 gcgtctacaa tagaggtata taataataga ttaagaaaaa ctataacaat aacacctgta
     1021 agtggaagag tacttctgaa agagggaaaa tatgaaacat aaatatggtt acttgctttt
     1081 ggaaagtgtc gtatcattgt cttcaatggt gataattata ctagttttat attctatatt
     1141 tttgtctaca ataaacttaa agttaaaagt agaagataag atagaactac aacaacaaag
     1201 tcttgaaatc ataaaatcta tggaaggaat tattagcaat tctatgggaa taatgaatgt
     1261 atctaattat gaagaaacat ttaaaaagac aacatctata aaatgtagat atttagatga
     1321 aaataataat gaagaaggca taagtaataa agaaattata ttgaatgaaa gacgaaataa
     1381 gttatttgta aattctttaa atggcgaaag tagtcaagca ggtggttatg aaattggaga
     1441 ttatgtagat gaaatgtatg tatcaattac taataatggt caatacgtta atattaaatt
     1501 gaaattatca aaatgtagtc aaaaatatga gactgatttc aaaataaaag tatggaattt
     1561 tagtgaaagt atataaaaat acataaattt aagagaaaga aatgacatca ataagtcata
     1621 taaaatataa ttattgagaa ctatataact aaataatatc aatatgtaaa gtgtatagat
     1681 taagaatata gaggataata ataaaaatat agaataagta atttgccaaa tacttgttta
     1741 tattgtataa cttatgatat tatgatatta gtaaaaattt gtaatcctga cttgacagaa
     1801 ttcaagtaag agatataatt ttaaaggcat agtaatgtaa aatttactaa aaaataagaa
     1861 atttatttta atatggagga acaaaaaatg gtatcagcag gtgattttag aaaaggtgtt
     1921 acatttgaaa aagatggaca accatgttta gtagttgatt ttcaacacgt taagccaggt
     1981 aaaggagctg ctttcgttag aactaaatac aaaaacttaa aaacaggagc tataagagaa
     2041 gaaagtttca atccaagtga aaaattccct aaagctgtta tagatacaag acaaatgcaa
     2101 tatctataca atgatggtga gttatattat tttatggatc aagaaaattt tgaacaaata
     2161 ccattaaact atgagcaagt tgaagatgca attaagttct taaaagaaaa tgaagttgct
     2221 acaataagat tttaccaagg acaaccattc caagtggaag cgccaaactt tgcagagcta
     2281 gaagttacag atacagagcc aggcataaaa ggtgatacag caagtaatgt aactaaagca
     2341 gctacagttg aaactggagc agttgttcaa gttccattat ttataaatac tggagataaa
     2401 gtaaagatag atactagaac aggtgaatat ttatcaagag tataaaaatt tatgtatata
     2461 aaagcttata tgtcttaata atataagata tatgagcttt tagtttatat ataaaaaaga
     2521 aagcgagggg tgttacatga aacatttata tgaagaagtt gcatacttaa aaggcctagc
     2581 agaaggacta gaaataagtg ctgaaagtaa agaagggaaa atgatacata aaatagttga
     2641 tgcattagaa gtatttgcag atgctattgt aacattggat gaagaacaag aagaacttca
     2701 agattttgtt gaatctatag atgaagattt agcagattta gaagaagata ttgctgacat
     2761 ggaagaagat ctttatgaag aagatgacga tgaggatgat gaggacttca gctatataga
     2821 aatggaatgc ccaaattgtg gagagttagt agaaatagac gaagatttgt tatatgatga
     2881 tgaagtagat gttgtttgtc ctgattgtaa ggctgtgata ttatcatcag aagatgattg
     2941 tgatgatgat tgtacatgtg gtggttgttc aagttgtgat gatagagagt aaaaattcat
     3001 aagaattaaa actgcctatg atgcctatga gatattttgc ttcataggta gttttatttt
     3061 tatgaggaag ggtattatgt attttggttt tgcaatactt ggacaaaaat agtacactag
     3121 aatttataga ataggatttt ggagggatgt aaatatgaaa ataagtaaaa aattactaga
     3181 taatatacaa agatttgaaa atgttataaa ttataaattt aaaaataaag aatatatact
     3241 agaagctctt actcatagtt catattctaa tgaaaataaa aaatataatt ttaacgaaag
     3301 attggaattt ttaggggatt cggttttagg catagtgata agtgattatt tatttaatga
     3361 agaagctaat ctgcccgaag gggaactaac taaacttaga gcaaatatag tctgtgaaga
     3421 ttcattaagt gaagtagcta atgatataaa tttaggtatt cacatgttat taggtagagg
     3481 agaagaagca acaggaggaa gacataggac ttcaatatta gcagacgcat ttgaagctgt
     3541 aatagctgct atatatcttg atggaggttt tgaaagtgca agacagttta tacttcatca
     3601 tatggaaaat ataatttatg attcaagaaa aggaaatata tttagagact acaaaacgca
     3661 tcttcaagag gtgttacaag ggaatggaga aaataatatc tggtacaggc ttatagaaga
     3721 aaaaggacca gaccataata aaagatttgt aatggaagtt ggaattaatg acgatgtact
     3781 tggtatagga gaaggcaaga gtaaaaaaga agctgaacag ttagctgcta aaatagcttt
     3841 aaagaaaaaa ttatgggaaa aataaatata atatgtaaaa atataaaaag aaatatttat
     3901 attagaagga tgttgtagat gaaaaagaga attataccta tatttgttcc tcacaaagga
     3961 tgtcctcatg attgcatatt ttgtaatcaa aaaaaaataa caggtgtgag tactgatgtt
     4021 actagtgaag atgcaagaaa tataattgag gaatgtttag agactataga taaagatgca
     4081 gatgtagaaa tagcattttt tggtggtagc tttactgcta tagatattga tatacaaaaa
     4141 agtttattat cagttgctaa agaatatgta gaaaaaggtc ttgtaaaaga tattagaatg
     4201 tctacaagac cagattgtat tgatgaagat atattaagta tgttaaaaga atataagaca
     4261 agtataattg aactaggagt acaatcctta gatgaaaaag tattattaga tagtataaga
     4321 ggtcatcaat ctgaaattgt atacaagagt tcaaagatga taaaaaatag tggaatcaaa
     4381 cttggattac agatgatgat tggtcttcca gctgacacag aagaaaagtg tatatttaca
     4441 gcaaaaaaat ttgtagagct aaaaccagat tgtgttagag tctatccaac tttggtagta
     4501 aaagatacag gtcttgaaaa gttaatggaa caaaataaat ataatccatt tacccttgaa
     4561 gagagtgtaa atatagtaaa aaaagttctt gtactgtttt atgttaataa tatcaatgta
     4621 ataagagttg ggcttcaagc tactgatgat atacaaattg gaaaagctgt tttagcagga
     4681 ccatatcatc ctgcatttag agagttggta gaagcagata tgataaaaga ttatttagaa
     4741 tttgttattt tgcaaaataa aaatataaag caaatgttgg tcaaatctaa taaaaagaat
     4801 atttctaaaa tcataggaaa taaaaaaaca aatgttaaat atatggaaga aaaatttggt
     4861 gtgcttttaa aaacacaaga atcagattta gatataaatc aattagaaat tgtgttagat
     4921 gggaaaagtt taattagtgc taatatgaga gacattcata gaaaattgta tgacatttat
     4981 gacctttagt tttaataatg aagggagaga aaagatttgt atttaaaaag actagagtta
     5041 aagggattta aatcctttcc agtaaaaaca gatattattt ttaaagaagg aataacagcc
     5101 atagtaggac caaatgggag tggaaaaagt aatatatctg atgctgtaag atgggtatta
     5161 ggagaacaga gtattaagag tcttagaggt gataaactcg aagatgtaat atttgcaggt
     5221 acagatacaa aaaaacctat gaattattgt gaagtggctc ttactattga taattctgaa
     5281 aatcaattgg aattagattt tacagaagta actataagaa gaagggctta tagaaatggt
     5341 gaaagtgaat tttttctaaa taataaaagt tgtagattaa aagatataaa agaagtcttt
     5401 ttagatactg gtattggaaa agatggttat tcaatcatag aacaaggaaa agtagatgaa
     5461 atattaagta ataatccttt aagcagaaga aaagtttttg atgaagcttg tggcatatca
     5521 aaatatagat ataaaaaaca ggaagcagaa aggaatttaa gtaatacaaa ggaaaattta
     5581 gaaagaatag atgatgtata tatagaaatt gaaaatcaat taaagcctct ttttaatcaa
     5641 cagacaaagg caaaaaagta cttggaaata agtgaaaaat taaagacact tgaagtaaat
     5701 agctttataa gagaaattga aggaatagaa aaagaattaa gtgaggttaa tgaacatcgt
     5761 aaggttattg aaaaggagct caatgaaaaa gaagaacaaa aaaatgttgt agagaaaaag
     5821 caagaagata ttaataaaga ggtagaggta ttacaagatg taattgaaaa atctgtagat
     5881 tatataaatt caattaaagg agttatatca aaaaaagaat cccaaataaa tttaattaag
     5941 gaaagaataa gaaattttac gaatgaaatt agtagaaaaa atttagaaat aaaggatata
     6001 aaagagaagc taaatgaaaa taagcaatac ataaaagaat tagaaagcaa taaattatca
     6061 ggtagtgaag aactatctac cttgcaggaa aatataaaag tattggaagg aagtaaagat
     6121 aaacaaaaaa ttaagttaga atccc
//
LOCUS       DAGQVA010000128         6087 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.132, whole genome shotgun sequence.
ACCESSION   DAGQVA010000128 DAGQVA010000000
VERSION     DAGQVA010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6087
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.132"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(111..518)
                     /locus_tag="MIV85_003616"
     CDS             complement(111..518)
                     /locus_tag="MIV85_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962915.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(992..1876)
                     /locus_tag="MIV85_003617"
     CDS             complement(992..1876)
                     /locus_tag="MIV85_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2962916.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2167..2643)
                     /locus_tag="MIV85_003618"
     CDS             complement(2167..2643)
                     /locus_tag="MIV85_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBY2962917.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            2909..4084
                     /locus_tag="MIV85_003619"
     CDS             2909..4084
                     /locus_tag="MIV85_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBY2962918.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4165..4968)
                     /gene="proC"
                     /locus_tag="MIV85_003620"
     CDS             complement(4165..4968)
                     /gene="proC"
                     /locus_tag="MIV85_003620"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBY2962919.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5008..5592)
                     /locus_tag="MIV85_003621"
     CDS             complement(5008..5592)
                     /locus_tag="MIV85_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962920.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2028 a         1023 c          679 g         2357 t
ORIGIN      
        1 agcaattcaa gtagtattgg ataggttcta tcctatctct acatataggt ttccctatat
       61 gctgactatt ttagctacta actcatgact aaagtcacga gtgtgtgtag ctatttttta
      121 atcaatattt tagtaaattt tacggtaagt aaaaacctct ctccttcaaa tcctatagca
      181 aatatactta caagttgctt tgagaaaata actcctaata tagctacaac tatgcatata
      241 ccaactatta tatttaaaac attgtttaaa aactttagtg cttgcttttc accttgttta
      301 ctacttatat cttgatacat tggaataaaa gtagtaacta tagcagtacc tattgctgca
      361 aatataatat ttggtatatt catagctgtt aaataactct ctgtatataa gcctgtacca
      421 taaattgatg ataatactaa ttctctaccc attccaagaa tcttagagat tatagtaact
      481 atcatcaaat aaaaagttgc tttagctacc ttgctcattt tatcactcca cttctaacat
      541 acctcttttt aatcaagtaa aatttagctc attagatata attctatcaa ctaatttgcc
      601 ttgcttagcc ctatcaaaat ataattaaca cctatttctt aatatatcac aaactacatt
      661 attcttcata tttttttatt tctccaataa gttttacatt tttcctatat aaattgtata
      721 gcttcaatta tattcaaaga aatggagttg ctacccgata actttaaaag taaaaaacag
      781 attttattat ctttttaaac tatattctaa catattttgt ccatattgag aaattttact
      841 aaactattat gtactttatt aaataaataa aataacagca cacctataaa atacaagtgt
      901 gctgttcata aacagatttt ataaaaaaat aattcctaag tagagattaa catgctttct
      961 catactctca tatataatgt gtctaaaaat attaataaaa atgttttaat tgttttaact
     1021 tacttggatg tcttaatttt cttattgctt tagcttctat ctgtcttatt cgttctctgg
     1081 taactccaaa tacctttcca atctgttcta gtgttttagg gtcatcatca tcaattccaa
     1141 atctcattct taaaacttgc tgttcttgct ctccaagacc tgtaagtagt tcttctatct
     1201 tttcttttaa attatgctgt tcaacttcgt gtattacaac atctttaaaa tcagcatctg
     1261 atggtataaa ttcaactaaa ctactatcct catcttcttt taatggagta tccaaagata
     1321 caacattttt atctcttctt aataattcca acactttgtc aacttctaag ccacatgcat
     1381 ctgcaatctc atctatagtt ggctctctta ataatacatt taaaagttct tgtttctttt
     1441 tctttacaaa atttattctc tgatgaagat gtataggtat cctaatagta ttttcgcaat
     1501 cgtcgatata tcttgttata ctttgtttta tccaccaagt tgcataagtg ctaaatttgt
     1561 atcctttttt ataatcgtac ttttctacag cttttataag tcctatattt cctgcttgaa
     1621 ttaaatccaa catatcaata ctatctcttt tatatctctt tgctatgctc actaccaacc
     1681 tataatttga atttataaat ttttcttttg ctactgaaga tgagttgatt atttccttag
     1741 ccagctctac ctcttctcct gctgacaaca ttttgtattc ctctatttcc tttaaataca
     1801 ttttcatcgc attcgataca tttgatgaac ccacacaaat ataattttca taattatttt
     1861 cttttttagt atccataatc aaaccccttc tattcataga atttgctaaa acaaaaataa
     1921 ataatttaaa cctacataat ctacaattac ataatatccc attctttaaa tgaattgttt
     1981 tgtatattat gtatacaaat ttataaaaac tatacctata atattattct acttctaaca
     2041 gcaatatcct ccttatatat ataatttatt ttattatatg ttgttatatt cttagttttt
     2101 tgaatgatat atgtctaaaa aaagactgtt tactaaacag tcttttttta tatatatgct
     2161 caatatttaa ttttcatgat gatgattaca tccacatcca caattttcat catggtgatg
     2221 atgttcttct aaatctttta cctgttgttc catttcatga aactctttta ccattatatc
     2281 ataagttgga agagctgcct cagtatcgta ttcttcccct ctccaatcag cgtacatcat
     2341 agcatctcca ttagttaaaa ccaatctacc tgacatagtt atattatcca cttcttctaa
     2401 aaattctatt tgtttttgta aaacttctcc ttctaactcc acatcttcat ctaaacattg
     2461 cactatcatt acaggtgcat aataatcttc ttcatcttta acatttacaa caatatctaa
     2521 aattccttct gcaccttctt caaattctgc caactcaaca tttgtatcaa tcatatcttg
     2581 aggtactaat aaatcttcta ttaaatattt tattactcta tcttttacta attcttttga
     2641 catttatttt tctccttccg attctataac attatcataa tcatttctat attatagtat
     2701 actacattaa ttgttttttc aatctcttac aaaaattatt ttttattatc ttccttatat
     2761 tccctttttt attacaaagt tgtaatcgca ttgatttaaa aaatagttta tatttagtat
     2821 aatagaaatg tagcacatat ttttattcaa tatattaata aaaaaatata ttgaaaatgt
     2881 aatgtatgtt aaatctagga ggaatattat gaagtttaaa aaacaaatta gttctattgt
     2941 tgtgtctact atgcttgtac ttgggagtat gaacctttct tatgcagacg gtacaaatgt
     3001 agttacactt ggagctaact tatcagagtc tcaaaagcag caaatgctta attactttgg
     3061 agtaaaaaaa gaccaagtct tagttttaga tgtaacaaat gcagaagaaa gacagtattt
     3121 acaaggtgtt gcaacagagg gtcaacttgg aaaagttact atctcttgct catacgttga
     3181 acctactaaa aaaggaaatg gaattaatgt taaaacagca aacttaactt gggtaactag
     3241 ttcaatgatt gcttcaaccc ttacaacagc tggtcttgaa gatgcaaatg ttattgctgc
     3301 tgctccatat cctgtaagtg gtactggagc attgacagga atcatgaaag catttgagga
     3361 tgcttcagga aagaaacttg atgaaactaa gaaagaaatt gcttctgaag aattggtagt
     3421 tacaggtgac ttaggagatg atatagggca agaaaaagca acaggtgtaa tgaatgatat
     3481 aaaaacagaa attgtaaaaa atggtacaaa agataccaat caaatagcaa atacaataaa
     3541 taatgttgta aataattaca atattactat tacaccagaa caaaaagaac aaattaaagg
     3601 tgtaatgaaa aaaatagctg accaaaatta cgattacaat agcatgaaaa atacactaga
     3661 taatgtatca gataatgtaa atgaacaatt aaagaaatta ggtgaaagtg ttaagggttc
     3721 tggtatacta gatactattg gtggatggtt tagtggaata ggagactggt tctctggttt
     3781 attctcaggc ggagataaaa aagatttggg aatcttaaat aatactaatg atgagtctct
     3841 tggctctgat gctgtaataa attctacaga aggtgttcaa ataaatccac aaaataatac
     3901 taattctaac aatgatagtg atacaaatag ctcaaaaaat gatacttcaa gtaataatga
     3961 aaataacgat agttctcaaa caaatgaaaa caacacaaca aataattcag aaaatcaatc
     4021 aaataataat gactcagttg gtttctttga aaaaataaaa aattggcttt caggcttatt
     4081 ttagaaatta aacaaataaa aagaattgcc taaaatggaa attttctata aaaggcaatt
     4141 ctctttattt acaataaatt tttattactc actcattttt ttagattttt ctatacatgc
     4201 acatattgct tttatcacag aagctctaaa accttcttct tcaagtactt taactgcttc
     4261 tatagtagtt ccaccaggtg aacataccat atcttttaat tcaccaggat gttttcctgt
     4321 ctcaagtacc atttttgcag aacccataac agcctgtgat gcaaacttat atgcttgtgg
     4381 tcttggcatt cctgcaatta ctgctgcatc tgctatagct tctataaata aaaatacata
     4441 tgctggtgca gaaccacttg caccaattac agcttctata agatactctg gtactacctc
     4501 agtatttcca aaagaattaa atacttctgt aactgcttct aagtcttctt tgtttatatt
     4561 tttatttata gaaagagaag acatggcttc atttacaaga gctggagtat ttggcatagt
     4621 tctaactatt tttttatctt ctcctataat agactctata tcttttatag attttcctgc
     4681 tgctattgta actataattt tattgtcatc tataaagtct tttatctctt ccaaaatatc
     4741 atcatatata tctggtttaa cagctacaat tactatatca gaggttctag ttacttcctt
     4801 cgagtctttt gtagtattta ttccaaaatt tgcatctatt ctatcaagag ttccttgact
     4861 atatgctgat gctataacca tattaggttc aactaatttt gaatttacta ttccccctat
     4921 catagcgctt gccatatttc ctgcacctat gaatccaatt tttttcactt tagtacctcc
     4981 ttattgacta atagtaatcg ttaaaattta agcttcttta actgcatcag acttttcaaa
     5041 tggatttggt atacttacta ccaaaatttt cactacctta ttagtatagt tgacccaatt
     5101 atgattgttc ttttcactat tatagtgtat tgtgtctcct ggatacattt ctatttgttc
     5161 atctcccaaa aacactgtaa gagtaccctc taatacatac acaaattcct caccttcatg
     5221 tacgtaacaa caaatttcct cactactctt acttggaaga atttcaatta atcttggtag
     5281 cattgttttt tcctttaaac tagatgataa atgataatgt ataaatgttg agttttctac
     5341 atcaaatact tctttttcat aacttcttaa tacagctctt ttatgctctt ttggcttcat
     5401 aaaaaagtaa gttaattcta catctagtac acttgctatt tttcctaagg aatctgttgc
     5461 cacacttgtt aatcctcttt caagttgtga taaaaaacca attgacaagt ttgttttttc
     5521 actcatatcc ttcagcgtca tttgcttttg agttctgagt tgctttattt ttgctcctat
     5581 gtccttattc aaaaccatca cccctaaata attttaattt tttcataata taaatacaaa
     5641 aatataaata taggtactga acctatcttt atttcattta aaaaaatttt tataagtatt
     5701 actataattt atcaatcttt ttttgtctac atttttacga ttatttacga tttatttttc
     5761 acatatgtat atttaatctt gccaactaaa gatacatttt ttataagcat ttactcttta
     5821 tataataaaa cttaagttgt tcatgagtct tcttctggtt taattattaa aatttcaaat
     5881 tatattatta tttctacaca ttattacatc ctttagtaca attataacat aattttacaa
     5941 tttaatgata tctattcaat gtcttttttt actctacaac atattttatt ttagagttta
     6001 atactatata tattttttat atacagcctt gtcatttttt agattgtcaa gagttattga
     6061 agtattttat gtagatttag attttat
//
LOCUS       DAGQVA010000129         5779 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.133, whole genome shotgun sequence.
ACCESSION   DAGQVA010000129 DAGQVA010000000
VERSION     DAGQVA010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.133"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..199)
                     /locus_tag="MIV85_003622"
     CDS             complement(<1..199)
                     /locus_tag="MIV85_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBY2962921.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTG"
     gene            complement(229..1494)
                     /locus_tag="MIV85_003623"
     CDS             complement(229..1494)
                     /locus_tag="MIV85_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBY2962922.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     regulatory      complement(1604..1706)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(1760..4417)
                     /locus_tag="MIV85_003624"
     CDS             complement(1760..4417)
                     /locus_tag="MIV85_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBY2962923.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFAPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     gene            complement(4545..5288)
                     /gene="yaaA"
                     /locus_tag="MIV85_003625"
     CDS             complement(4545..5288)
                     /gene="yaaA"
                     /locus_tag="MIV85_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBY2962924.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            complement(5298..5762)
                     /gene="bcp"
                     /locus_tag="MIV85_003626"
     CDS             complement(5298..5762)
                     /gene="bcp"
                     /locus_tag="MIV85_003626"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBY2962925.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
BASE COUNT         1760 a         1079 c          712 g         2228 t
ORIGIN      
        1 atcctgtttt atctatcctt cttagtaaat ctaattctgt atctatcttt ataggcatta
       61 gatttagtat agctatctta gtgtctatgt tttcttcata ctttaattcc tttttaaaat
      121 cttctttata aattacatct attccttcat ctaataattt attaataaca ggtaatccct
      181 ttggtagtat taaagccata tcttttcact tctctttctc ttagaatatt agaaatttaa
      241 agcttgattt aaatcagcta ttaaatcctc tacattttct attccaacag ataatcttat
      301 tagtgaaggc aatactccag atgcaattaa ttgttcctct gttaattgtc tatgagtagt
      361 tgaagctgga tgtataacac aagttcttac atctgaaaca tgtgtaacca aagatgctat
      421 ctgtaatttt tccacaaatt ttttggcatt ttctaaccca cctcttactc caaatgataa
      481 aacaccacta catcctcttg ataaatactt tttggcattc tcataatact tgttatcttc
      541 aagtcctggg taattaatcc aatctacatt ttcatgtttt tctaaaaatc tagctatttt
      601 aagtgcattt tcactatgtc tctccattct aagatgtagt gtttcaacat ttaaattagt
      661 aagatacgca ttgaatgggc ttaaacaatt tccatagtct ctaagcaact gaactcttgc
      721 tttagttgca tatgcggcat ttccaaattt ttgagtatag cttataccat gatatgttgg
      781 gtctggctca actaattctg gaaattttcc attatcccag ttaaagtttc caccatccac
      841 tataattcct ccaacacttg aagcatgccc atctaaatat tttgtggtag aatgagtaac
      901 tatatttgct ccatacttta aagggttaca aagcactgga gatgctaatg aattatcaac
      961 aataaatgga acattaattc tcttagctac atttgctatt ttttcaaaat ctatgacttc
     1021 aagagttgga tttgcaagtg tttctgcaaa cacaacctta gtattttcct ttgcaagttc
     1081 tactatctca tcttcacttg aatctaagtc aaacgatatt aaatctatac caaatttttt
     1141 aagactaggt cctagtaaat tgaatgttcc tccatatact tttgaagaac aaagtatact
     1201 atctcctgat ttacatatat ttaaaactgc caacatattt gcagattgcc ctgatgatac
     1261 agctacagaa gatactccac cctctagtaa acttattttt tcttcaaaag cttgaatagt
     1321 aggattgctt attcttgaat atatatgtcc atcaactttt aaatcaaata attcagcaag
     1381 ttggtctata ctgctatatt taaaagttgt actttgatat aaaggtagta ctcttggttc
     1441 tccattacct ggtttataat ttccttgcac acatattgtt tctttattat acattcttgt
     1501 atccccctta gattttagta aaaaaaatta aactatttac cagatgagag ttaaaataaa
     1561 taaagcctga gtatataact caggctctgt ataagcttaa ttatactcat ctctcagctt
     1621 tcgccgcagg atttagcacc actgtatata aatatactgg ttgccgggtt tcatagggcc
     1681 agtccctcca cctctctgga taagatttat ttaatttttc tatgttttat atcttatata
     1741 tttttcctaa ttttgtcaac tattttttta atttttttct tttaataatt ttcccaacct
     1801 ctacttgaat tacagacatt atggctaaaa caatcgttat aagccactct aagttattta
     1861 aaactgttaa gttaaaagca tttctaaaaa caggtgcaaa tagtattact gctattaaaa
     1921 atgcagaagt taaaaatgag attaaaagaa atggattttt accattattt ctattaaaca
     1981 ttgaatctgt atttgaacgc tgactaaatg ctcgtaacat ctgtgaaaat gctaatacac
     2041 aaaatgccat tgtttgacct acagaatgat tttctatatt aagaccaatt ttatatgcta
     2101 aaatagtcat tattgccaca aatatacctt gggtaacaac tctttgtata agattttttt
     2161 caaacaaagt ggttgatttc actggctggt gcttcattat atttctgctt ggtgggtcaa
     2221 ctccaagagc aagggctgga agcgtagcag ttgcaaggtt tacccataga atatgaacag
     2281 caagaagcgg agtatcccaa tttaataata ttgctacaaa caacgtaagt atctctgcta
     2341 tattaccaac aagcaaaaat tgtataactt tttgtatgtt tctatataca cgtctacctt
     2401 cttttattgc ataagcaatt gttgtaaaac tatcgtccat taaaatcatg tcagaagaat
     2461 cttttgcaac atctgtacca cttataccca tggctatacc aatatcagca gactttaagg
     2521 caggagagtc atttacacca tccccagtca ttgctggtac ttctccaatt ctttttagag
     2581 attgtataat tctaagttta tcaaatgggg atacacgagc aaatactgta gtatttttaa
     2641 cagcttcatc tagttcatca tcactcaaat tatcaagttc atcaccagat atcacagtat
     2701 tttcttcact ccatattcct aactcatgag cgattgttgt ggcagtaact ttatggtcac
     2761 ctgttatcat tatggttctt atacctgctt ctttacaagt acttactgca tcaattacct
     2821 cagttcttgg tgggtcaatc ataccaacca tacctataaa tgttaaatca tattctatat
     2881 tttcactatc ttcttttggt atagatgaaa tctcacgctt agcaaaacca agtacacgca
     2941 atgcatcttt agacatgtta agacataatt cgtgtatatt ctttttatcc acttcggtaa
     3001 tgtttctttc accttttgaa gttaatattt tagtacatag gtcaagaatt tcgtctactg
     3061 ctcctttagt ataagcaata atcttttcat ctatattatg aacagttgtc atacattttc
     3121 tatctgaatc aaaaggctgt tcaaatacac gtggatattc ttcttcaaga gcttcttgat
     3181 ctattccaaa ttttttggcc ataaaaatta atgcgccctc tgttgggtca cctaatattt
     3241 catctgtttt atctggatta atacatgcat cattacaaag tgcaccagca taaacaatct
     3301 ctttatacac taatggatgt ttttcagatg cagtatctat tgatgtcact tttccagatt
     3361 caaaatctcc attgacagca atatgtgtaa cagtcatttt atttaaggtt aacgtaccag
     3421 ttttatcaca acatattact gtagctcctc ctaatgtttc aacagcaggt aattttctaa
     3481 ttaaagcatt tcttttagcc atacgctgta cgcctaaagc cattacaata gtagctgttg
     3541 caggtaatcc ctctggaata attgatatgg caagggaaat tgcaatcata aacattggca
     3601 agagaggtct ctgataaaat gcacctattg caaatataac aacgcataca ataataccta
     3661 tgacacttaa tgtctttcca acagtattaa gtttacgttt tataggagta tcaaaatcat
     3721 cttgtgaatc taaaagatgt gctatgttac ccacttctgt atccatacca gttgctacta
     3781 caacacctac acctctacca tatgtgacta ttgaagatgt atacgccata ttgctacggt
     3841 ctcctaatac acattcttta ggtaagattg tatctgcatc tttttctgat ggaacagatt
     3901 ctcctgttaa agaagcctct tgaattttta aacttgatgt ttctattaaa cgaaggtctg
     3961 ctggaaccat agctccatct tctaaaaaaa caatatctcc tactacaaga ttacttgctg
     4021 gaataacatt ttcttcacca tcacgcataa cacgagctgt aggtgagttc atatttttta
     4081 atgcttctaa tgatgattct gcttttttct cttgaacaat tccaataact gcatttactg
     4141 ttacaattat tagtattaca aaagcttctg taaattcgcc aaatatcaaa gataatattg
     4201 ctgctcctat tagtatcata accatagcat ctgtaatttg actccaaagc atttgtaaag
     4261 ttgttctagg tggttttttt ctaagttcat ttaagccatt ctctttaagc cgtttttccg
     4321 cctcggtatc ggtgagcccc tcctctgatg aatctagact ttctaaaatt tcatgcgttg
     4381 ctcttgaatg ccaaggcatc tgtttgtgat tttccatttt ggaagaccac tcctttcttt
     4441 ttttaattta agaataatta tattttaaaa tcaagttcaa ttcaatacac actaagtata
     4501 ttttacctaa atttaacaat gccatttaat atttaacaaa acttctactc ttttacaaat
     4561 atgtattcac tattgttaga taagttttct ttatacttat aaccttctaa attaaacttt
     4621 ttcagttctt caatatctct tatcctattt tttacaatgt attttgtcat catacctcta
     4681 gctttctttg cttgtgtaga ttccactttt aatatgccat ttttatttac tttaaaagta
     4741 catgtaatat atgtatcact atctttaata aatttttcta tggatttgct gtattcattt
     4801 gatgaaagat taacgatagc tgttttttct ttgattagtt ctttatatat acgatttccc
     4861 caatattcgt ataaattctt aaactcacct actcgtaatt ttgtctgcat ttctaatcta
     4921 tattcatata tactatcata tggttttaca acaccataca atccacttat gattcgaata
     4981 cagctatttg caaactcttc atctttcctt gtaaaatttt ctgcttctat atttttatat
     5041 tgtattccat cataagttaa gattgcaggg tttcctaatc tatcaaattt aatgctttca
     5101 aatctatttt tatttaatac agctaatttt tcattaattt tcattttatt tttaaaatct
     5161 tctataccaa atgtctttat attttccact atttcttttg tgttatctat aaagcaaggc
     5221 aaactcaaat ctctatcaaa tacttctata ttcttcatat ttttagctgg tgataacatt
     5281 ataatcataa attcttatta ctcctgtttt tccaaatatt caagaatctc ttgtgcattt
     5341 gtgtctggtt ttgctttttc aaagactttt tcaataattc cattttcatc tataatatat
     5401 gtcgcacgta caactcccaa tgcagttttt ccatacattt ttttctcttt ccatacatca
     5461 aaagctttta tagcaactaa gtcagggtca gaaagtaaaa taaaaggaag ttcatgcttt
     5521 tctgcaaatt tttgatgtga ttttatacta tctttactta tcccaataac ttgtatatct
     5581 tcctttttaa atccatcata tgcatttcta aaagcacaag cttgacgtgt acatcctggt
     5641 gtattatctt taggataaaa atatactact acttttttgc ctttaaaatc tgacatactt
     5701 accttatttc catctttatc ttctagtgta aattctggtg cttttgttcc tatactcaac
     5761 ataaatatct ctccttttg
//
LOCUS       DAGQVA010000130         5751 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.134, whole genome shotgun sequence.
ACCESSION   DAGQVA010000130 DAGQVA010000000
VERSION     DAGQVA010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.134"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            260..379
                     /locus_tag="MIV85_003627"
                     /pseudo
     CDS             260..379
                     /locus_tag="MIV85_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            506..1408
                     /locus_tag="MIV85_003628"
     CDS             506..1408
                     /locus_tag="MIV85_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBY2962926.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKDRGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            2020..3033
                     /locus_tag="MIV85_003629"
     CDS             2020..3033
                     /locus_tag="MIV85_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBY2962927.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQVNVY
                     IDN"
     gene            3385..3954
                     /locus_tag="MIV85_003630"
     CDS             3385..3954
                     /locus_tag="MIV85_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBY2962928.1"
                     /translation="MKKRLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYFNRYN"
     gene            complement(4290..5627)
                     /locus_tag="MIV85_003631"
     CDS             complement(4290..5627)
                     /locus_tag="MIV85_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBY2962929.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
BASE COUNT         2126 a          582 c          963 g         2080 t
ORIGIN      
        1 ttcctcttga gggaagtaca ctacaagcta ttggtagtgg aagtgggtag accttaacgg
       61 ataatgccga aggataagat atagtctgtg cttgcatgaa agtgtaagaa gttcataaga
      121 gaactgcata ggtagtagcg aacttatgtg aacgacaacc tcaaaaatga taaaagttaa
      181 gacttacggt tcttaaatat gttatttaaa attaaatata aaaccttcta aataattgtt
      241 ttaaataatt acatttgtta acattattat aagagaatgg atttgtccta gttgtaatga
      301 aactcacgat agagatataa atgcaagtat aaatatatta aaagaaggat taagactaat
      361 aacaattcaa aataaataac ttatgtaaga accgtaggaa ctacggggat agcctgtgga
      421 gaattagtaa gacatatgtt agtatgcaaa attctatgaa gcaggaaccc tgtgacttta
      481 gtcatgggag gttcagattg gaaatgtgtt gccacaagat tattatggat taatagtgat
      541 tttaggtgtt attcttggag ttatgggggc attttacaac tggtttactc tatatgtgca
      601 gtctttatac aagaagattc ctaaaattgg tacctttgga aaactgttga ttccatttat
      661 aatggctggt attcttgggc ttgttatgcc tgatgttctg gggagtggac acaatttagt
      721 tgaagaactt acaagtcatg aatatatttt tggaatggtt gttttgattt ttgttatacg
      781 ttttatattt tcggctgtta gttttgggtc aggtgcacca gggggaatat tttttccatt
      841 gcttgtttta ggagcattta taggtggaat atttggtatg gtaggtgtta aagtttttgg
      901 aatgaatccc gattatgtaa ataactttgt gcttttggct atggcaggat attttacagc
      961 tattgtgcgt gcccctttga ctggtatcat attaattttt gaaatgacag gttctgttag
     1021 tcaaatgctt tcactatcag taatttcaat tgtggcatat attgtggcta cacttatgaa
     1081 gtctaaacct atttatgaaa gtcttcttga gaggttactt gaaaaaaatg gagaacctgt
     1141 acataaagat aggggcgaaa agatactaga ccagttctct gttatgtttg gctctcctgt
     1201 tgcgaacaag gcaattcagg atgtacagtg gcctgaaaat tgtcttttgg tagcaattca
     1261 aagaggtgga gaagaaatta ttcctagagg taagacaatt cttagaccaa gtgatgtaat
     1321 tgtgactatg acagatgaga gagatagtgg tgctgtgtat gataagatgg aaaatttgtg
     1381 taaagaacat acggcacata ttttttaggg agaatgatga atgtttaata atgatagaat
     1441 atttaatgaa gatttgatta aaaaattggt aatttgaaag agagttaagg aattaatata
     1501 agaaaatgaa aatgtgatat cttagatgta aaagagtttg aagaaaataa ttgtatatat
     1561 ttgttaatga gattatatgg actaatggta tatttatact gtgctaaaag ttgtactatt
     1621 gtatgaggaa tgggaataaa gggtttgaaa aaataggtag aagatttttc agatattctt
     1681 attgggatat tttaattaat atattttaat tgcgatattt tgggaagaat agaatttatt
     1741 tataaatgaa aataattaaa aggggttaag gttgtattag ccccttttgc ttatagagtt
     1801 tggaaatggt atcttgatag cagttgtttc atgcttatta tattttatta catattttaa
     1861 aattgacctt attactccta aatcattgtt ctatcaactt ttaaaacact ttcaagacaa
     1921 tcgcctattg aaaacaaagt taattaaaaa cctacatatc agtttagtat tcgtgtagat
     1981 gattatataa atataaaagt ataagaaagg tgagtatctg tggttagttc atttttaaat
     2041 gatatcttta gaacaatttt agtaagttgt atttttatag ttattttatt agtctttaga
     2101 ataactttat ttaagatttt cagtaaaaaa tttaattact atatatggct tattgtgatt
     2161 attaagctat cattaccatt tatgaattat acttttatat ttaatgagtc aaaatataat
     2221 ggtaatatta ataagataag tttaggcaat tttaatagta tttctattgt atatagtact
     2281 gttttagtct ctgtttggat tgctattacg atattttatt tagtttatac tttattgaaa
     2341 tatattaagc ttaaaaatat gataaatgat ttgtcttatg atgttgagga tgataagata
     2401 aaaaatcttt atgaaaattt attaaaagag cttaagataa ataaaaaaat acggcttaaa
     2461 tattcatatg aagttgaaag tccagtattt tttaattcgt gtgtcatttt accaccatgt
     2521 gattatacat taaaagagtt aaactggata tttaggcatg agttgatgca ttttaagagt
     2581 aaagaccttt atattaagta tttggtgata tttttaaaat gtgtttattg gtttaatcct
     2641 tttgtgtata taatggagaa gtttatagat ttggattgtg aattttattg tgatgaaaga
     2701 gttttgaaga attgtacgat agaagagaag caggattatg cattgacaat aattagtgca
     2761 atgagaaaag gttcaaatag ttcaaataaa tttgtggctg gattacataa ggagtcagat
     2821 attaaaaaaa gagtgtttag tatgtttaat gaaaagtaca gaaatggtat tttgatagca
     2881 gttattttat gtttattatc ttctattaca tattttaaaa ttgatttaat tactactaaa
     2941 tcaatatttt atccactttc aaaacaaaca cctattgaaa acagaactaa ttcaaaacct
     3001 acatatcagg ttaatgttta tatagataat taaaaaatac aaagtttaac aagagattaa
     3061 tataaataat tttaataagt atctttcaca tatgttaaat ttactttaat tatattaaag
     3121 ccaatgaatt attctttaga agctccaatg ccagtaaata caggtaaaga aaaaattact
     3181 acaattgtag attaaaaatg ttctaatatt taaagaaatg caaaagtgta agaagggtaa
     3241 aaatctgtta taatacatta aaaactaaat ttagaaaaat ttacataatt agaaaaatga
     3301 tttgataaaa aataaagtta aatattaact aagtaaattt gaaaaagaaa aaatataaag
     3361 tacaaattta aaaggaggta actaatgaaa aagaggttgg aagatatgac tttagaggag
     3421 ttatggaact tgtttcctat atttttgact actcacaaag aatgttggaa aaattggttt
     3481 aaagaagaac aatatagact aactggaata ttaccaatgc aaaaaattgt tagaataagt
     3541 catattggaa gtacttctgt gagtacgatt tatgccaagc ccattgttga catactgatt
     3601 gagataattc ctgattataa tatgaaagat attaaagatt tgattgagtc gaatggatat
     3661 atttgtatgt ctgagagcag tagtaggctt tcacttaata aagggtatac agtagatggg
     3721 tttgaagaac gagtttttca tttgcatata aggtatgtag gtgataatga tgagttgttt
     3781 tttagagatt acttaattga ccacccagat gttgcaaagg agtatgaaaa acttaagttg
     3841 gacctttgga agaagtatga gcataatcgt gatgcttata cagatagtaa actagatttt
     3901 gttagggagt ttactgaaaa ggcaaaggtg ttgtatttta atagatataa ttagaaatag
     3961 gtacaattag atatttatct tatatattgt attatatttt ttaagaaagt aattaataga
     4021 aaaagggctt gtttcaaaat ggagagataa atcccttttt cattgttgaa aggataaaaa
     4081 tatatttgat ttcatgtaaa aaagagtgcc tcatcaacta aaaagtttat tttgagacac
     4141 acacattttt actaaggtaa ataaaatatc acatttgatt aaattttaag ttaatgaata
     4201 tatgtgtaaa tatttaatta taagttatta taattttaca tagtatcaaa caatctaatt
     4261 tgtattatat aagataatct aattttagac taaaataatc taatataaag aaataaagaa
     4321 aattcattct cagtataaga aatatccaat tttccattgt acttattaac aatttctcta
     4381 atattctcaa taccatatcc gtgagaatta ctatcttttt tatctgaaat aaatagttct
     4441 tgttttctat tgataggatt taccttgttg tttgtcaata aatagctaaa atactccttc
     4501 tcacaacgtg cctttaatac cacttttcta tttgacaaat caggaatttt caaagatgct
     4561 tctatagcgt tatctaaaga atttgaaaaa atagtacata aatctatagg ttctataccc
     4621 aagtgattgt ctatatctat attaaagtgc acatcaacac cattttcttc caaacttgta
     4681 tgacgaagat ttaaaattga gttaagagct tggtttttgc aaaattgttt gccactaaga
     4741 gtacctatac ctatttttaa ctgattaaaa tactttttag ctccagcaat atcttcaatt
     4801 tctaaatacg attcaatcat ttgaaagtga ttattcatat catgtcgcat tttgcgtatt
     4861 tgaatttgtt gattttctag taagttatag tatttttctt ttaggtgatt tgcttgtttt
     4921 tctatcttca tctttacatt ttcaatcaat ggctgtaaaa gaagtatcac accgatattt
     4981 gccagaattg ctgacaagat gattagataa gtgccataag gtaagttgcc taagataata
     5041 ttcttattac tacccatagg gattaaatta gtaggtggca gaataatagc aattaatatt
     5101 gataaaaatg aagatataca caccatatca ataaaaatcc atattttatt tgataagtat
     5161 tgttttatat tgaccaatct attctttagg aaaatatgta ttaaaaacca aaataataat
     5221 ttaattagag cagaaattat ctggactatt gaaagtatta aaatatactc ttttgagtgt
     5281 ataagttcct catatatagg gttgtttata aaaagaaaat taagcccaat tataatagga
     5341 taaagtatca tgacaactga tattatagga attaatttgc ttttgctaca tattataagt
     5401 agtataaaat atccgaatag tgtaaacaaa atatttacgg ggtcggaaag ccatattatc
     5461 atttgactaa taatagagta gcccaaaatc aatatgattt tgaaaatcca atgattccta
     5521 aagtctataa aataggaagt caacttataa agaaaaaagg ctatgaaaat attgattaat
     5581 attagaataa aatttatgct tgtagagatt aaagaataag tgcccattta atataccttt
     5641 ctattaatta agattctgga aactaagttt taaaaaatta aatcttaaaa attaaaattc
     5701 tggaaattag atttcaaaga attgattttg aaaaataaaa ttctagaaat t
//
LOCUS       DAGQVA010000131         5536 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.135, whole genome shotgun sequence.
ACCESSION   DAGQVA010000131 DAGQVA010000000
VERSION     DAGQVA010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5536
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.135"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(623..2029)
                     /locus_tag="MIV85_003632"
     CDS             complement(623..2029)
                     /locus_tag="MIV85_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2962930.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2074..2781)
                     /locus_tag="MIV85_003633"
     CDS             complement(2074..2781)
                     /locus_tag="MIV85_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962931.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            2952..3866
                     /locus_tag="MIV85_003634"
     CDS             2952..3866
                     /locus_tag="MIV85_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2962932.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QKLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3866..4627
                     /locus_tag="MIV85_003635"
     CDS             3866..4627
                     /locus_tag="MIV85_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962933.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAITRNPD
                     MLGGFEYSYMFMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4639..5376
                     /locus_tag="MIV85_003636"
     CDS             4639..5376
                     /locus_tag="MIV85_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2962934.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         1928 a          845 c          703 g         2060 t
ORIGIN      
        1 tttatttata tattacaaag tttaaatttt ttcattaatt atattataaa tttcccatat
       61 atttcaacat aaatacatat atatatatgt tatttctaaa aatactacac aaaaactcta
      121 ctttagtaga actcaatggc gcaaaatact tcaatttaaa acatttatcg tactttaaat
      181 aaataactat aataatatac ttacaatagt tacatagaag ctattataac tacacagaac
      241 agcgtataat taaaactttt ttaggatgtc attatatttt ttcttaaaat taaaaaacac
      301 tataccataa ttctatttta gtagaatttt tttgtcaata ataaaattaa atattaacta
      361 aaaaataaaa aaaatggaat tatctaaaga atttaataac cttacaataa ttccaaaata
      421 ttatttctat gaaaattttg ataccatgag taactcagcc ataagcgcat aaagcacaag
      481 ttactcttta ctttaataaa acttgacaag aaaagaattt atccttattc tactctaata
      541 gagttaattt gtcaataaag aataaaatta ttttcaaaat attttcattc ttcattctta
      601 tctgttatta ttttataaaa tatcacttaa ttagaggtaa ttttagtatt gtttttagtc
      661 cctgactatc aatgctcgta atatctaatt tacctctatg tgcattaata atgccagata
      721 ctatcaaaat acctagacca tgattttgac ctttggcata tgcctcactt agtccatttt
      781 ggctctttaa taaactatta attctttctt gactcatacc ttttccatca tcttcaacaa
      841 ttatatagca aaaatctaaa tcagacttag aggtaaccct tatattacat ccttgttggt
      901 tatgagttat actattttgt attaaattac taatagccct ttttaataat tttttatctg
      961 catctataat aatatcttca tttagtatat caagttcaac gtaaaagtca ttatccaaat
     1021 tattatttat aaactcagaa ataagctctc tcaaaaacgc agaaactcta atcttatcac
     1081 aattcaatgc ttgcatatta tattcaagtt tagacactaa atttaggtca tttactaatt
     1141 ctctgatttt aatcccttga ttgcatataa tagacacttg ctcttgttct ctatttgaaa
     1201 ggctactgct ttcttcaagt tctccagcat atccaattat cattgaaagt ggagttctta
     1261 tatcatgaga tattcctgca atccagttag acctagcttc ctctttcttc ctaagttttt
     1321 catctttcat ttgcaactct ttagatacag tattaataga ttttgaaata tcacttagta
     1381 ttcctttttc ttgtaaaagt actggttctc cttttgacat aagctttatg ccagtaataa
     1441 ttggttttat agatttcacc atttttaaac ctatgaatag agctattaaa aaagtaacta
     1501 ttgcattaac caaaaacata cctattatta acataggaaa ttgttctatt tccttaaccg
     1561 tataagtaag gttaaactta gtgtacttgt cttttggata acctgttact aatattccat
     1621 ttggatgttc ccatacatac acaggatagt cctttaaaaa gaaccttgaa aactttgcta
     1681 catctgtcaa agtataatga cttggaattt cttttggtaa atcaaatccc catattctat
     1741 ctccattgtt atcaattaac attgcccaaa ctttattttt atgtagtact tccttactag
     1801 aatcatctaa aataaacttt ccatttctta aaatcaaatt atcttcaatc ataatcaagt
     1861 ttgattttat ttctctgcta tcacttgtat ctaaattatc agagtattta gatacaaata
     1921 gcatatatga aaacagaaga aaacctgcta tatttaatac aataaaaagt aatgaaatca
     1981 agatacttga acctataaat cgcctcaata tgtactttac actatccaaa attaaatcac
     2041 tcctcttgat ttcttttatt ctaatatcta aaattaatta atcatcaact tatatccaag
     2101 acctcttact gtaataagat gtttaggtgt agatggagtt ttttctatct tctctctaac
     2161 ccttctaaca tgaaccataa gggtattttc atatccatac atatcatctc cccaaatggc
     2221 ttgacatagt gaatcattag taacaattct ccctttattt tcatacaact ttaaaagcaa
     2281 cgaatgctct ttagctgtta aagaaatctc ttgcccatct ttctcaacac atgcactatt
     2341 taaattcaca acaacagaat ctcccagttt aaatactggc aactcctctt cttctatagg
     2401 cacatataca cgatttaata tacccacaag ccttaaagta agttcctttg gtaaaaatgg
     2461 ctttactata taatcgtcag cccctaagcc caaaccaatc aatctatctt catcttcacc
     2521 tcttgcagag agaaaaatca ctggtatttt agatgtctct ctaatttttc tcataataga
     2581 aaaaccatct ccatctggca atacaacatc taaaattgca caatctggct ttacatttct
     2641 aaatacccta acagcttcct cataacttga tgctaaaaat actctactaa acccctcttt
     2701 tctcaggatt tcatctatca tttttaataa ttccttgtgg tcatcaacca caagtatttt
     2761 tttatctttt attgactcca taatcatcac cctcctttag tataccatat acccattttc
     2821 acaactttgc ctaaatagac ttttaaggtt attgtaaggt aaatttcagc taattgaaat
     2881 gtaaccaagt tattatactg atataagtta aaagaatcaa taagcacaga ttaaaaaagg
     2941 ggatgaaaca tatggaaatg ataattagaa cacaaagact ttcaaaggaa tacaataaaa
     3001 tatttagagt aaaggatata gacctaagag ttccacaagg agctgtatat ggttttttgg
     3061 gtcctaatgg agctggaaaa tctaccactc ttaaaatgct tcttggactt gctaaaccca
     3121 cacaaggaaa tattaatatt ttaggtaaag agttaaatga aaaaaataga atatcaattt
     3181 taaaagatat aggttctttg atagaatctc catcatacta tggtcatctt acagggcttg
     3241 aaaacatgac cataatgcaa aaactcttag atttacctaa aaaaaatgta aatgaagcat
     3301 taaaaattgt aaggttagaa aatcaaaaaa ataaaaaagt tagtcaatat tctttaggta
     3361 tgaagcaacg tcttggtatt gctatggcaa taatgaagtt tcccaaatta ttaatacttg
     3421 atgaacctac aaatggactc gacccagcag ggattgagga aattagagaa ttaataaaat
     3481 ctctaccaga aaaatacggg atgactgttc taatctctag ccatctttta agtgaaattg
     3541 accaaattgc cacatcaata ggaataataa atcatggcga actggttttt caagatagca
     3601 taaaagaact tcataataga ggtcaaagtc agattgctat caaaactaag aatgttgtat
     3661 ctgcacaaaa actattaaat actaaaggat atatgtcact tatacaagat gggtacttga
     3721 ctattgaaaa tttaaaagac tcagatgtgg ctaaaataaa tggtatgctt gtccattcaa
     3781 atatagatgt atttagaata gaagaacata aaaaaagctt ggaagatata ttcttagaac
     3841 ttactggtaa ggcggtgact ttataatgaa ataccttggt ctagaatttt ataaacttaa
     3901 aagaaagaag attattctga tgaccttttt atttgtagct gttgaaataa tgtggtgtat
     3961 cataaattca aatagagcta ttacacgtaa tccagatatg ttaggtggat ttgaatattc
     4021 ctatatgttt atgagttttg caagtttaaa tggtctattc tttcctatct taatatcaat
     4081 aattacatca cgtataagcg atatagaaca taaaggagat acatggaagc ttttaaaatc
     4141 ttctgtgaca tctttaaata gtatttattt atctaaattt ttatgttctg ctattttggt
     4201 atctatacct gtattgatgc aagtgttatc tattgtgttg tttggacatt ttagaggggt
     4261 tattgagtca atttctgtat ctttactttt aaaatacaca ttaggaacaa ttcttgtaag
     4321 tattgctatc attgcactac acctatggat tgcaactgta attccaaatc aaatgattgc
     4381 aattacattt ggcatgattg gtagttttat aggtttgaca tcaggtttgt tttatcaagg
     4441 tattcgtaga ttgtttatat ggtcttatta cctagagtta tcacctttaa gttatgctta
     4501 tgataatgtt ttaggttcat ctgtctatag aattgatatg aatttttcta ttacgatttt
     4561 agttttctta attggaatgc taatttatta tattggaaga aatcatttat taaaaaaaga
     4621 agtataggag ggatttaaat gttaaggaag tcagttttgg gagaaattct aaagttaaaa
     4681 aattctttta tatggtatgt attattagct ttgccactta taagtgtgtt gattggttct
     4741 ggtaattttt atctaaatca aggcatactc aaaaaagaat ggtacagctt atggactcaa
     4801 gttagtcttt tttatgggga atttttcttt cctatcttaa tcgcaatctt ttgtgcatat
     4861 atttgtaggc ttgaacatat gaatcataat tggaataatg taatgacact gccagttaat
     4921 ttaaaaaata tctttttatc taaacttaca gtagtttcaa tacttacagc tattacacaa
     4981 gttttctttg ttatctttta tatagttgca ggaaatatgt ttggtttttc tggtagtgta
     5041 cctaaagaat tgactggttg gattgctaaa ggttggatta tttctatttc aatagcttct
     5101 atacaattat acatgtctat aaagattaga agttttgcaa ctcctattgg tattagtctt
     5161 tgcctttctc tatttggtat gggattaata gtagcaaaac ctgctgttgg tatatttttc
     5221 ccttattcta tgttaggtag tgctatgggg gttataaagc aatctgcttt aaatgttaat
     5281 gacactatag ttacaatatg tgttgcattt attactacta tagtattttc tgaaattgcc
     5341 aatagaaatt ttagaaagaa tgatgttatt tcttaatggt aaatgctaga tattttgggg
     5401 tttgaaattt atattctttt tagttgaaat ctatatccat tttatttaaa aatatatatc
     5461 ttttatttga attttatatg ttttatctac tcgctatata atagatatac tcctaaaatt
     5521 aaaaaatata taataa
//
LOCUS       DAGQVA010000132         5518 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.136, whole genome shotgun sequence.
ACCESSION   DAGQVA010000132 DAGQVA010000000
VERSION     DAGQVA010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5518
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.136"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            44..160
                     /gene="rrf"
                     /locus_tag="MIV85_003637"
     rRNA            44..160
                     /gene="rrf"
                     /locus_tag="MIV85_003637"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(374..1558)
                     /locus_tag="MIV85_003638"
     CDS             complement(374..1558)
                     /locus_tag="MIV85_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBY2962935.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPVFIDTKKENGFKLTKDELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1931..4282
                     /locus_tag="MIV85_003639"
     CDS             1931..4282
                     /locus_tag="MIV85_003639"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBY2962936.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4304..4843
                     /gene="nrdG"
                     /locus_tag="MIV85_003640"
     CDS             4304..4843
                     /gene="nrdG"
                     /locus_tag="MIV85_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBY2962937.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2151 a          624 c          889 g         1854 t
ORIGIN      
        1 aaacttatta aaaacttaat agaaatatta agcataaaga ttatgtggtt acaatagcag
       61 agaggataca cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac
      121 ttggtgggaa actgcctggg agagtaggac gtagccacgt aatttttttg ttataataaa
      181 tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata aaagacttat
      241 tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa gttgttgaat
      301 atatcttata ttacttacct tatatattaa ttatcattaa tacattatat ctaattacta
      361 ttcatctaaa ttattatgcc attattttat atacaaattc ttttaattta tctaatccag
      421 ataagaaagt attttcactg caagcatagg atatacgaat atatttatcc ataccaaatg
      481 ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa aattctatag
      541 aaaaactatc tttatattca aatttctcag atactttaga aagatctata aatatataga
      601 atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt gatttaatta
      661 aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag caatctttca
      721 aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga tgtccttgta
      781 tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat cttaatccag
      841 tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta gcttcttcgc
      901 ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat atttcatctg
      961 ctaaaatata tattttattt tgtatgcata catctactat ttctattaat tcatcttttg
     1021 tataaacact accagtagga tttgaaggat tgtttattac aagaattttt gttttatctg
     1081 ttatagattt ttcaagttca tcttttgtta acttaaatcc attttctttt ttagtatcaa
     1141 taaaaactgg aacagcatta actaacttaa ccatttcagg ataactaacc caataaggct
     1201 ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt gttattgagt
     1261 tttttgctcc acttgataca actatttcat ctattgaata gttacagtta ttttcttcaa
     1321 taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa tcatatttag
     1381 tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt acattaaaat
     1441 cgggttctcc tatactaaga tttattactt taactccatt actttccatt tctttaactt
     1501 tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt gataacataa
     1561 aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat ttacataagg
     1621 aaatttgtag atatatacat taatatatat aatagcctac actttttgcc taaaattagt
     1681 gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgcta ctgttcaaaa
     1741 tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca aatttggtaa
     1801 tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga tttttttaga
     1861 cttaacatac tacatatagt ggtatgggga ttaataaaat acaatatata gtaacaggag
     1921 gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc catttaatga
     1981 agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa gagaaggaat
     2041 agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt ttttaaatca
     2101 taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag ttaaggttct
     2161 tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa ctgaaagaag
     2221 tagaataaga aattcaaaaa caagattgat gaaggcaata gaggaaatta cctttgaaga
     2281 tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata cagcaatggg
     2341 aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac atatattaaa
     2401 accagagcat tcttttgctc atgataatgg agatatacac atacatgata tggatttttt
     2461 aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca atggtggatt
     2521 ttcaacagga catggctttt taagagagcc acaagatata ataagttatg gtgcattagc
     2581 tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta taccattttt
     2641 cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca taggaaattt
     2701 agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa agaacatagt
     2761 atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg aattgtatct
     2821 aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac ttgtaaataa
     2881 gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa catatcaatc
     2941 tatggaagca tttatacaca atctaaatac aatgcactct agagcaggtg cacaggtacc
     3001 attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg taactaagaa
     3061 tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt ttccaatttt
     3121 aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt atgatttatt
     3181 taaattatca tgcagagtat cagctaaaag actattccct aattttagct ttttagatgc
     3241 gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta catatatggg
     3301 ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg gtagaggaaa
     3361 catatctttt actacagtaa atttaccaag attgggtata aaacatggta ttataaataa
     3421 tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa acttaattat
     3481 agaacaatta ttggagcgcc ttgaggtaca aggaaataaa aagatgaaga attttccatt
     3541 cttaatgggg caaggtgtat ggaaaggttc tgatgattta ggaccagaag atacactaaa
     3601 agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag agtgccttat
     3661 tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag gattaaaaat
     3721 agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat taaatttctc
     3781 cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag ataaaaaagt
     3841 ttatggagaa attaaaggta tcacagataa agaatattat actaattcat tccatgtacc
     3901 agtttattac aatataagtg catatgataa aattgagata gaagctccat accatgaatt
     3961 gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg ataatttaga
     4021 agcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg gaagtataaa
     4081 tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa gtaatatatg
     4141 ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa ttcgaaagaa taagaagaat
     4201 aacaggatac ttagttggta cagttgatag atttaataat gctaaaaaag cagaagtaag
     4261 agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa taagaatgtc
     4321 atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg taatatggac
     4381 tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg atttatgtgg
     4441 aggattttat atggatacag aagaaattat aaataaagtc aaatcattga aattacaaaa
     4501 aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag aagaaatagc
     4561 aagagaagct aaaataaatg ggttagatgt atggtcatat actggattta cgtttgaaca
     4621 actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa agcaaattga
     4681 tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa agtttagagg
     4741 gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaaa aagtgttttt
     4801 ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa ataaacagga
     4861 ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa gcttgtataa
     4921 tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt atagtttata
     4981 ggtgttttat gtggattacg aatgatatag tattgataca ttatttaata gattcttatg
     5041 ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat ctagataagt
     5101 tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt gtgaatatta
     5161 agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac taaacacata
     5221 agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat gtaatatcta
     5281 tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat aatgtggata
     5341 atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg gataatatta
     5401 taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt tgttgactct
     5461 aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca aataaagc
//
LOCUS       DAGQVA010000133         5400 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.137, whole genome shotgun sequence.
ACCESSION   DAGQVA010000133 DAGQVA010000000
VERSION     DAGQVA010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.137"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(127..810)
                     /locus_tag="MIV85_003641"
     CDS             complement(127..810)
                     /locus_tag="MIV85_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBY2962938.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(986..1576)
                     /gene="zapA"
                     /locus_tag="MIV85_003642"
     CDS             complement(986..1576)
                     /gene="zapA"
                     /locus_tag="MIV85_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBY2962939.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(1601..3994)
                     /locus_tag="MIV85_003643"
     CDS             complement(1601..3994)
                     /locus_tag="MIV85_003643"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBY2962940.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(4011..5030)
                     /gene="pheS"
                     /locus_tag="MIV85_003644"
     CDS             complement(4011..5030)
                     /gene="pheS"
                     /locus_tag="MIV85_003644"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBY2962941.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(5080..5314)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1637 a         1067 c          596 g         2100 t
ORIGIN      
        1 taaaatactt ctattaactt atacattgct tactatattt taaattcttt aattaatcta
       61 tgcaatattt gctatatata aagtatatca aataacagct tcattttttt gtaaatttac
      121 agaaagttaa ttttcattaa atgaatcatc tttattgata aacataattc caaagaccac
      181 tgccaaaata aaaaaacata ttagtattga tttttccacg aaaatttttg taaaaaaagt
      241 tcctaaaata gctccagata taaagaatat aataatagca taatactgta aactcttttt
      301 tatcataaaa atattcttag tatgtatata atgaaataaa gtttctgtag cacttcttaa
      361 atttccagta cacattgtcg ttgcaaaact attcccattt acttttctaa aactctctac
      421 ttgcattgaa caaataaaag aaatagcaac atttacaaac atattaaatc ttcctctagg
      481 aataaatgaa acaataagta ttgtaatcat ttcaattata atgataacct gacgccaatg
      541 aatctttgtc ttattatttg taaaatactt tcttatcttc tcggctataa atacacctaa
      601 cataaatgcc aaaataggaa tcaaataata aaatgattcc tttacattac cttctgctat
      661 attaagccca aacaaaacta tatttccagt ttgtgcatta gcaaagactt tacctcttac
      721 cacataagta taaatatcca aaaatcctcc tgttattgcc aacaaagaac ataaaaagaa
      781 tgattcagac atctgactct tgcttgtcat atataaacct ctcgctttct aatgatagat
      841 acaaaatcaa aatcatttta gattctattt ttcattgata taaaaaaatt atttatattt
      901 aaatattgtc tatatttata catcatttat atttatacat taaaagaagc tgtctcaaaa
      961 aacaagagac agcaaatctt ttagtttatt ccacattttt tgcatcatta tttaaccctg
     1021 tacattttaa ctgtaaatca taagctttgt tttgaaactc agaagctaag ttttcagcta
     1081 tagtagctct ttcatttgct tcttcaagtt gagtacttaa ctcctcaatc ttgtttttat
     1141 aagcatctaa ctctgctcta gaaccttctg tcgtattact aagttcgaat atttcttgct
     1201 ttttattttc tataatctca attaactctt tcatcttagt ttcagcttca cgattttctg
     1261 cttctttttc tgctatcgta agctttaaag acttgatttc taattgaagc tcttcattag
     1321 atgctccaac cttcttactc aattcttcat tagctttaat caacttctca ttctcatctg
     1381 aacattcaaa taaaaggtct gatatattta atgcagttaa tatcgcagca actgataagc
     1441 tcaatttcgg gttttgacgt gttattttat ccatttcttt gtctacaaaa tcagcaatac
     1501 taatcataaa cttctctgat ttgtctccaa ccattggata ttcagcgcca tggattttaa
     1561 ccattacttt gttcatccta acctcccccg acattagttg ttaatttgat cttaagttag
     1621 catttaattt ttcgcttaat tcacttaata tcttatcatg caccttagct acatcttcat
     1681 ctgttagagt tttatcttta cttctataag ttattgaata tgcaattgac ttgtatccag
     1741 cttctatttg agaacctttg taaacatcaa ataacttgta gctttctact aatccttgac
     1801 cattttcctt tattatatct tctatttgtt ttacaaatac atcatcttta acaataagag
     1861 ctatatctct tgatgtagat ggatattttg gtaatggcac ataattcttt gttctatcag
     1921 aattatcaaa tacaaagtca atatctattt cagcgacata aactctttga cctagattgt
     1981 agttttctat aacatctgga tgcaattcac ctaatgtacc tacatattta ttattataca
     2041 ctattttagc acatctacca gggtggaagg tagtattatt atcttgaggt tcaatttcat
     2101 aacctttaaa tccgacattt acaagtatag tttctatagt tccttttagt gcaaagaagt
     2161 caacatcttt accatacata cctacacaca ttctattttc ttccttaggt aattctgaat
     2221 cttgtgggat gaatatatgt ccacactcaa atgcagatac ttcttctatt ttatgagata
     2281 cattagttga taaaacatct aacatatttg gtattaaagt agttctcatt acagaagttt
     2341 cttctcctaa tgggttaagt aatttaacaa aatttctctt tgcattacct tctggtactc
     2401 ttatcttatc tactccctta gggcttacaa atgaatatgt taatatttca tttaatccta
     2461 cagcagttga attatctttt aaagcatcca tgaatttttg ttttgaagtt ttaattcctg
     2521 ctgtcgtatt tccttctaat tgtacagaag gtatattctc aaatccataa attctagcta
     2581 tttcttccca tacatcagct tcttgttcca tatctgttct aaagcttggt acatctattt
     2641 ctaatttatc attagctacc aaattacatt taaactctaa tgattctaaa attcctacaa
     2701 actgctccat tggtacatct acacctaata gatggttaat tctttgagga tttactacca
     2761 attttttagg ttctggttta tttggatata catctacaac accttttaaa acttttcctg
     2821 ctcctaacat ttcaacaagc tgtgcagctc tatttgctgc tatctctgca agattagggt
     2881 ctaagtcttt ttcatttctt gaagatgctt ctgacctaat accaactttt ttagctgtca
     2941 ttcttatgtt ttctggtttg aaattggcac tttcaaaaag tacagtcttc gtattagaag
     3001 ttatttctga gttagcacca cccattacac cagctaaacc aagtgatttt tctccatttg
     3061 ttataactag catatctttg tctaatgttc tctcaacatc atctaatgtt acaagtttct
     3121 ctccatcttt agcatttctt actactattc ttccagtctc tacttgattt atatcaaaag
     3181 catgaagtgg ttgaccaagc tctaacatta cgaagtttgt tatatcgact atgttactta
     3241 taggtcttac tcctgcttct gtaagtcttc tttgcatcca atatggagaa ggttctattt
     3301 ttacatctgt aaccattcta gcaacatatc ttctacataa atctggatta tctatctcaa
     3361 ctttgaaatc tatctcttcg tcactttctt ttacttcgat ttcaggatat tttacttttg
     3421 ttcctatagt tgcagctgct tctctagcta tacccatcat gcatttacaa tcaggtctgt
     3481 ttgaagttaa ttcaaaatct attaaagcat cttttaatcc taaaacatct tttatatctt
     3541 ttcctaattc ataagaatct tcgtggtcta aaatatatat accacctctt ttatactcct
     3601 caatgtaatg ttcatctata cctagttcag ctgctgaaca catcatacca tctgataatt
     3661 cacctctgaa atcagtctgt ttgatttcaa ctcctccagg taacttagaa ccatttacag
     3721 ctactggaat ataatctcct tctgatatat ttgtagctcc tgtaactatt tgaacaactt
     3781 tatctccaat atctactttg gttacaacca acttatcagc atttggatgt tgttttattt
     3841 ctaaaatctt tccaaccaat atattttcta tttcttcacc ataataatct attgtttcaa
     3901 ctttagttcc tgtcattgtc attttatcag cgaactcttt tacatccatg tctatatcaa
     3961 catagtctct aagccatttt aaagatacta acatctacat accctcctaa ttaaaattga
     4021 tttaagaatc tcatatcatt ttcgaataat aatctaatat catctatttc gtatttaagc
     4081 attgcaagtc tttcaacccc aactccaaat gcaaatccac tgtaaacttc tgggtctatt
     4141 ccacaatttc taagcacatt tggatgaacc atacctgaac ctaatatttc tatccaacct
     4201 tcatatttac acattgggca acctttacca ccacatttga aacaagtaac atcaacctct
     4261 gcacttggtt ctgtaaatgg gaagttgtga ggtctaaact tagttttgat atcagaacca
     4321 aacaattttt caacgaagat atccatagtt cctttaaatt ctgccatagt aacatctttt
     4381 ccaacaacaa gcccttctat ctgatggaac attggtgagt gtgtagcatc tggcgagtct
     4441 gacctaaaac atctacctgg tgcaattact tttattggta actcttgact tctcatagtt
     4501 cttacttgaa ctggagatgt ttgagttcta agtaataccc catcattgat atagaatgta
     4561 tcgctcatat ctcttgatgg atggtcttta ggagcgttta atgcgtcaaa gttgttttca
     4621 acagtctcaa cttctggccc ttctgctata gagaatccca ttccgataaa tatatctgtt
     4681 acttcatcta taatttgagt tattggatgc ttcttcccaa cctttaaaac ttttcctggt
     4741 tgagtaacat ctatcacttc ctcttttaat tttctttctt tttcaatagc atttatttct
     4801 tcttttttag aatttatgct aagttcaatg ttttctctta cctcattggc aaccttacca
     4861 actactggtc tttcttcagc agataattta cccatttctt taagtatggc agttatctca
     4921 cctttttttc ctaagtactt aactcttaaa ctttctacac tttctatgct ttgtgcttct
     4981 tttatttcag ccaaagctgc ttcacgtaaa gcaagtaatt tttcttgcac acatatcacc
     5041 ctttcgtttt tttgtataaa aaaagcccct caatccctgt ctagggacga aaggctatag
     5101 tttcgcggta ccaccctagt agtttaacaa tttaaaaatc atcaaaccac ctctaacaaa
     5161 cttaacgcgt ttttgacgtc aaagcctact gtaaaatttc agctctgtta ctccagaggg
     5221 aacttctcat gacctcttag aaaacactcc cagcctaggt gtttatctct ttactaagtt
     5281 taatcaaaat actttcctct ttcattgcat ttacaatatt atattgttta ttttagtatt
     5341 atatcatttc cattcaaatt atgtgactat ttttaatata tatccaatac ataattaatt
//
LOCUS       DAGQVA010000134         5139 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.138, whole genome shotgun sequence.
ACCESSION   DAGQVA010000134 DAGQVA010000000
VERSION     DAGQVA010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.138"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(425..2560)
                     /gene="rnr"
                     /locus_tag="MIV85_003645"
     CDS             complement(425..2560)
                     /gene="rnr"
                     /locus_tag="MIV85_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBY2962942.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGVIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3153..3767
                     /locus_tag="MIV85_003646"
     CDS             3153..3767
                     /locus_tag="MIV85_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBY2962943.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTNRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3785..4147
                     /locus_tag="MIV85_003647"
     CDS             3785..4147
                     /locus_tag="MIV85_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962944.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4253..4750
                     /locus_tag="MIV85_003648"
     CDS             4253..4750
                     /locus_tag="MIV85_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBY2962945.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1696 a          784 c          644 g         2015 t
ORIGIN      
        1 cacttctatt aagcatttct caattactta tttttcaatt agccacttct attaagcatt
       61 tcttaattac ttatttttca attagccact tctattaagc atttcttaat tacttatttt
      121 tcaattagcc acttctatta aacatttctt aattatttat ttttcagttg gctttttcta
      181 ttaaatgttt cttaattact tatctttcag ttagctcttt ctattaaaca tttctcaatt
      241 acttattttt caattagcta ctttcattaa atatttctta attatttatc tttcagttaa
      301 ctatttccat tagatatttc tcaattacct atttttatca tttattttat agagtattgt
      361 gcactatata tttatacata tcataaatac tacaacttgt tatctcttat tttagctgtt
      421 ttatctactc ctctattttt tcaactatct caaagtcaat ttctttaaaa tctacattaa
      481 cactttcaac ctttatctta acaaggtcac ctatcttata tgacttctta gttctttctc
      541 ctaaaacact ataagaactc tcatcataaa tatagtaatc atcattcata tttgcaagtc
      601 ttatcacccc ttctatggta ttatctaact caacaaatat tccaaatgaa gttacgctag
      661 atacaacacc ctcaaattct tgaccaactt tatccttcat ataaagagcc ttatagaaat
      721 catgtacatc tctttcagct aactctgcct ttctttcttt ctcggatgat tgaacagatg
      781 cataatccac tatagtagta agctgttctt gtctttttcc acttatttta ttatttaaag
      841 attcttttat tattctatga atttgaaggt caggatatct tcttattggt gaagtaaagt
      901 gacagtagaa tttagctgct aatccaaaat gtccactaca ttctggtgag tacttagctt
      961 gttttaaaga acgaagcatt atagtactga tagctccttc ttcttttttg ccctttattt
     1021 tctctattat accttgtaat gcttttggat gtacttcctc tttatcacct tttattatat
     1081 atccaaatgt agatataaac ttactcaatt cttccatttt ttccaaagat ggtgtctcat
     1141 gtattctata cacaaacggt attcccatcc agtaaaaatg ttcggcaatt gtctcattac
     1201 ttataagcat aaattcttct attatcttat tagatattct tctttcatat ggctttatat
     1261 ctacaacttc gccttttcca tttagaatta tctttgcctc tgggaaattg aagtctatag
     1321 ctcctctttt ttcccttctt gacataagaa tcctagctaa aatttcagca tttttaaaat
     1381 cttcaacaac atgttcaaaa gtctttttaa gtttttcatc atccttttct aatatatcag
     1441 atacttctgt ataagtcatt ctagcttttg aatttattac agattcacat atttcatgtt
     1501 taaccacatt tcctttatgg tctatttcca taaatataga aagagttagc ttatcttcaa
     1561 atggatttaa gctacatact ccatttgaaa gagtttttgg caacattgga attactttat
     1621 ctactaaata aactgatgta gctcttttta aggcttcctt gtcaagttta tttttctctc
     1681 ttacataatg tgtaacatca gctatgtgaa ctcctagttt gaagtttcca ttaggtaata
     1741 cttctattga tatggcatca tctaagtctt ttgcgtcatc tccatctata gtaaatatgt
     1801 ttaaatctct taaatctctt cttcttttta tctcttcttg aggaatctca acagctacag
     1861 cttctgcttc ttgcaatact ttctttggaa attcttctgg aagaccatgt tctcttatta
     1921 tagaatctat ttctacgcct ctttcacctt tttgacctag tatctctata attttgcctt
     1981 ctggttttct atcctcttgt ggccatactg taatttcaca tactacctta tcattatcta
     2041 ctgctccact aaaatgtttt ttaggtatat atatatcttt agtaaatttc ttgttgtctg
     2101 gtgttacaaa tccaaaagtt ttacttgatt ggaaggtacc tactattcta gttatttctc
     2161 tctttattac ttttactatt cttccttctg ctctcttttc ttcagttgca ggtactacta
     2221 tttctgccat aactctatca ttatgcatag caccatttat attgtcactt gagataaata
     2281 aatcctgtgt atattcaaca tcagattcta caaatccaaa accctttttg tgtgatacaa
     2341 attttccaac aaagtatccc atttgattgg gagatactat ttttcctttt ttagtaaagc
     2401 agatataacc atcttcttct aattcattta aaaaattata aaacattggc atttctgatg
     2461 aatgtatatc aaatatttct gctaattctt ctttttttag aggattatat gcactttcat
     2521 ttattaatcc tagcaaactt tctttaagtc ctggtatcat ttttccctcc tgttttactt
     2581 ttcattatat tattatttat attgtctttt atatttcttc agacaaaaca ttttttactt
     2641 atcacataat tttctatatt ttcttattat tataagttaa aattacttat ttatattttt
     2701 gatttaatgt aatctttgtc atactaactt caaacaaatt atgatgtttt ataaattatt
     2761 tgtaaatatc attataatta cttaagttat tctttatcat aattgcttaa attactcttt
     2821 atcacctaat tatacaccat caaataggat tggtaaaata ttcatctcat ataagtatta
     2881 ctatataata atttattcta ttagtatact caaatcatgt aaaatttata taactcaatt
     2941 aattttttaa atacaacttt ataatataaa acttataata aaagtaaatt tatatgttaa
     3001 atgaggttga ttttttatta ttttttattt atgctagtac taaagacttg caaacgtttt
     3061 ttgacaagtc tttattttgt ctaaattaaa caaacttttt tacaaataaa tacataaaat
     3121 ttaaactaat ctatttattg gaggagataa aattggaaga agtaattgca aaaattatta
     3181 ctatagaaaa tggattcaaa gaaattgaaa acattgctaa aaaaattgta aaaaataatg
     3241 actcaaaaaa gtgttattat ctatcaatct acttatatag gtcagaatat tatcaagtaa
     3301 gagaattggc tgtgtttata cttggtttta tatcagtaac tatttctgaa gctttgttat
     3361 ttttaaaaga taatgtgagt aaagatgaaa actggagagt acaagaaata ctagctaaat
     3421 catttgatta ttattgcagt gaagtaggat atgaaaaggc acttcctgtt ataaaagaat
     3481 ggcttaattc tgatagtcca aacataaaaa gggctgtgac agaaggtctt cgaatttgga
     3541 ctaatagaga ctattttaaa tctaatcctg acgttgctat atcactactt tctagtttaa
     3601 aagaagatga tagcgaatac ttgagaaagt ctgtaggtaa tgctcttaga gatataagta
     3661 aaaaatatcc agatttagta aaaaaagaat tagattcatg ggatatatca aataaaaaag
     3721 ttgagtttgt atataagctt gcttcaaaat gtatcttggc aaagtaaaat ggaggtgaac
     3781 ttatttgaaa cttcgtgatg agtatacttg cccattagaa ctaacacatg atatgataaa
     3841 aggcaaatgg aaatctatta tattatggag attacgcata ggaccaactt ccttatcaaa
     3901 acttgaaaag gaaatcaatg gtattaatca aaagatgtta cttgaacaac ttaaagaatt
     3961 aattgaattt ggtcttgtag ataaaaagac atatgaaggt tacccactta aagtcgaata
     4021 ctcacttaca cctattcgag ggaaacaaat attggatgct ttggctataa tgcaagatat
     4081 aggaattagc tttatgttgg ataatggtat ggaagatatt cttaaggaaa aaggtgtttt
     4141 aaaataaata gatacccaca aaaaagtaag taatttacca ttattttcaa ctggtatata
     4201 attaaattat agatatattc tattaattta ttataatagg aggtaaatta ttatgaaagt
     4261 aactagtaca ggtatagtaa atggtgttat agaagataaa tatggtaaaa gaggaactca
     4321 gttcaatgaa ggtggtatgc ctacatattc actacctcta aagtttgaag atgctccaaa
     4381 gaatacagta tcctttgctg tatttttaga agataaagac tctgttcctg tatgtgggtt
     4441 tgcatggata cattggttag ctgtaaatat aacaaaagat gagttaaatg aaaatgaaag
     4501 tgtaacagct actgattttg tacaagggac tactagttgg catggtaaac taggaggtct
     4561 tgacagatta gaggccagtg tatatggtgg aatggctcct ccagacagac ctcatgtcta
     4621 tgaaatacat gtatttgcac ttgatactat ccttgacctt gaaaaaggat tctatatgaa
     4681 tgaatttttc aaagctattg aagggcatgt tttagataca tttacactaa aaggaagtta
     4741 ttctaattaa ttaggttgac tatagctaat cattaattaa atgatacatt taattgatga
     4801 ttagcttaat tgttattaga atattttctg cactttatct taatatatat tttagttgac
     4861 tggtatttta atttctatta gattattatc aatttatata aattgattaa aaaatagcta
     4921 cgcacactcg tgactttagt catgagttag tagctaaaat agtcagcata tagggaaact
     4981 tatatgtaga gataggatag aacctatcca atactacttg aattgctaaa aacccctaaa
     5041 gctaaccaaa ctaaaacata aggatgaaat aaacctaagt gtgaaagtta cgaaagtaga
     5101 aaaaattggt tagatggtat aaggttaaac cctaagtac
//
LOCUS       DAGQVA010000135         4865 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.139, whole genome shotgun sequence.
ACCESSION   DAGQVA010000135 DAGQVA010000000
VERSION     DAGQVA010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4865
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.139"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            379..633
                     /locus_tag="MIV85_003649"
     CDS             379..633
                     /locus_tag="MIV85_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962946.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            669..992
                     /locus_tag="MIV85_003650"
     CDS             669..992
                     /locus_tag="MIV85_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962947.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIF
                     IDYII"
     gene            1266..1418
                     /locus_tag="MIV85_003651"
     CDS             1266..1418
                     /locus_tag="MIV85_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962948.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            1612..2535
                     /locus_tag="MIV85_003652"
     CDS             1612..2535
                     /locus_tag="MIV85_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBY2962949.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   2802..3482
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2802..2829
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaa"
     gene            3674..3826
                     /locus_tag="MIV85_003653"
     CDS             3674..3826
                     /locus_tag="MIV85_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962950.1"
                     /translation="MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            3946..4760
                     /locus_tag="MIV85_003654"
                     /pseudo
     CDS             3946..4760
                     /locus_tag="MIV85_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
BASE COUNT         2009 a          439 c          868 g         1549 t
ORIGIN      
        1 catatgttag tatgcaaaat tctgtgaagc aggaaacctg tgactttagt catgggaggt
       61 tcaggctagt attactcatt attgtattca aaagctaaag tggaaaccta gtgaatatat
      121 gaatttagaa gttaatgaga gagcattagc agccgactca atacttatta aaattgaaga
      181 tgaagaagaa acaatgaaag aagctgaaag agagaaaaag agaggtagaa gaaggtagaa
      241 tttaaagtta aaatagttac attgctaata tatgaaaatg ttacaaattt ggaaatagat
      301 ggatatatat gttgtatagt ataatgtaga taatatatca ccaagtaaaa aacaacaaat
      361 aaatctaaat tatgaggggt ggaaaataaa gatattaaac ttacaatatg tatatttgct
      421 tttgtaattg gaataatagt gttattttgc tgtataggtc taggtcaatt taatatggat
      481 tgtattataa aacaaaatgg tgggtcaata gctaccgaac aatacaacat atatttagaa
      541 caatctattt cacaatatag aaattttggt tctatactgg ttttactagg aggaatagga
      601 atactgtttg ataaaagtgt cagaaaatac taaaaaagta tatttttatt taggatgtga
      661 tgaatgatat ggcaagagat gtatttagtg taaagatgac accactagaa gcacagaaaa
      721 tggtagaaaa aaatttggaa gcagatttag tttctgttga tatttataac ctagaaaata
      781 ataagtctat aatagttaca atctttgaaa aatattatgc aagaagcaat agtgatgcag
      841 gtttggtagt gatttgtgaa aatactacag gaaaaacact tgttaaaatt acctcaactg
      901 gtagtgcaat tggactattt cagattgatt ggggaacagg taataatttg attaaaagag
      961 taaaaaaaat atttattgat tatattattt aattatttta tgtagatatt cttaggttgg
     1021 tatggaattt gtactaacct attaagtaat caataaaact aaataaacat agaaagcact
     1081 tacaaatatg taggtgcttt ttattgaaaa aatagaaaat aaaataaaaa gtaagatata
     1141 ggaaaaatat gtaagaatta tatgttataa taattgtagc aagaagatgt aatctacaat
     1201 ttatagagtg gagttcatgt attaaaaaat tatcctccca acgataagaa gggaggtgaa
     1261 tatacatgga taatttttta tttaatgtgt tagctagtgt aacagctagt tacatagttt
     1321 atttgattag caagttaatc aaaaaagtaa aaagccactc taccgcaaag agtgacttaa
     1381 agattgatat aaattttaaa tatcatcgta aaaaataact ttcagttata gaacttcact
     1441 ctaccgcaaa tagattgtag ttcttcttgt ttttattata ccacaaatta gaaaaaatat
     1501 tgcatataat attttttata gtcaataaaa atatgaaatt ttttatacac aatgatgatg
     1561 aatctaacta gatgaataaa tttaattgta aataagaaag tacttactta aatggtaggt
     1621 gcttttgttt tgccaaatta tgctataata ttgagtgaga tgagtaattt gtgggggaat
     1681 tttataatgt ggatattagt accaataata acaatagtat tacttataat agctgtttct
     1741 tctatgcaat atattttagt tatgatagct tttttgttga ttatatattc ttttatagaa
     1801 aagaaaatag ttatgggtct tgtgtcagtt ctttttttca cttattcaat ttatctttgt
     1861 gcaacttggg aagataaatc cttgatagca gataataaag ttgagactgt taaggcacaa
     1921 agagaaactg tagaaagaga aaaagaaatg gaaagaagaa gaatacaaga agaagtagac
     1981 aaagaaagat atattgaaaa acatggaatg gaaatatcag aaaatgattt aaaagttaag
     2041 ctagaggctt tagtacctca agaatataag gggaagaaat atgaattaaa agtaggaaaa
     2101 tttaaaagat atagtatgta ttttgattta actgtacaaa atgaaaaatt tagtaattct
     2161 gaagaatgta aaaaatttgt aaaagaaatt gctaatgatc ttaaaaaaat taaaataagc
     2221 aaggcgtact ttaagtttca ttcaaaagat gacggcggta tatataattc tgtttatatt
     2281 gattatttta gaaacataca aaataatgta gataatgttg aaaatttaga attcaatgag
     2341 tttgaactta aaaccgaaga agaagagaag cgagaacaag agaaaataga acaagaaaaa
     2401 aacagttata ataactacat tcaaaacaga gtggttgacc cactagatag aataaagaaa
     2461 ctaaaagagt tgctagattc aggagcaatt acacaggaag aatataataa aaagaaaaaa
     2521 gaattattag aatagataat atagtaagca cttacaagta tgtaggtgct tttaaattta
     2581 caaagtattc cattttaatt ttatagttta gattttatga tataataaaa atatagaagt
     2641 tttgcagtgt gcgatatttg ttacaaagta gggcttaata cttgaaatct aagatgttga
     2701 gggtgcgtga taagtgttat caattgcact attgcccgct cactgcaatt ttaagagtat
     2761 tgtatatatg taggtattgg aaatgctaag tttattttgg ggttttagat taactatatg
     2821 gaatgtaaaa ctgactcggg agcatataat aagtaatatc aagaatagtt ttagattaac
     2881 tatatggaat gtaaaattcg taaaataaca attgtcagga atatgagaag tttgttttag
     2941 attaactata tggaatgtaa aattggactc aaaatataag ttaaaaaaat ttttaagttt
     3001 tagattaact atatggaatg taaaaatttt tgacgctatg aagaaattta ctacaaaatt
     3061 tgttttagat taactatatg gaatgtaaaa acttttttca tcctcccaaa cctcttgttc
     3121 gctgtcgttt tagattaact atatggaatg taaaaaagaa aataagttta aaaaaaggtt
     3181 tcattattat atcgttttag attaactata tggaatgtaa aaccaattat gtacagttta
     3241 gttactgtgt taagtcttgt tttagattaa ctatatggaa tgtaaaatcc ttttataaat
     3301 atcttctgac atgtgtatat gcttgtttta gattaactat atggaatgta aatcggctac
     3361 aacggtataa attaaattta gcagggtaca ttttagatta actatatgga atgtaaattg
     3421 ctgtgatttc aataataaaa caattaataa ttgtgtttta gattaactat gtggattcaa
     3481 aattaaataa acaaagaaag cacttacaaa tatgtaggtg cttttattct gctcaaaatt
     3541 ggtcggttgg gtaaaataat tagaaaaagt tagtaaaaac ctattgactg taactcgtta
     3601 caatattgtt attaatgtaa cgagttacag aaaagaggtg aataaaatag caactaaaag
     3661 tagggcagag tatatgaaaa atcgtcgaaa agataaaaga ggttttagtg tacttttaga
     3721 caaagaaaag ttagataaat ttgatgaagt gttagaggaa aagaatctaa ccaagaaaga
     3781 atggctagaa gaaaaaatcg acgaggaact ggaacaaaag gaataaaaaa taagggtcac
     3841 tcccaccgac caaagtttga gtaaccccta tgacgtatac tatcgtatat caattatagt
     3901 atatgtcatt ccttaaaaaa atcaattatt aaggagtgta atattatgaa aaatgaatta
     3961 atgatgtttg aaggaaaaga gattgaagta tttgaatttg aaggaagaat tttattcaac
     4021 tcaaaagatg tagtaaactg tttagacata aaaaatgtta atgagaatat aagacttatg
     4081 aatgaaaagc aagttgtaaa gttaagaaat tcggatatca gtaatactga catccgaaaa
     4141 cttaataatg ctggagaaaa ttttcttact gaaagtggag tgtataaatt aatctttaaa
     4201 tcaagaaaag aagaagctga gagattccaa ggctggataa gtgatgaagt tttaccaagc
     4261 ataagacaaa ctggtgcata cataaataat aatgcaatac cgaaaagttg agagaaaaag
     4321 caagtgagat tgaaaaatta cagttggttt ataacagtac atctatgtta aaagaattgc
     4381 tagatgatgc aggctttgac aataaatcaa aactattaac agctaaaaca ttatataaga
     4441 aagcaggaat tgatttacca atagagataa acgaagaaga acattatttt gatacaaaac
     4501 aaatagcatc taaactgaaa atatattcta agagtaataa accagctcag atggcagttt
     4561 gtgagattat taaaaagatt gatttagaag atggtgaagt taaaggtgtt tgggaaatta
     4621 atggttcttg gactggtact gtaaataaat atacaaagag tgtaatagat aaggtgagaa
     4681 cttggataga ggaaaataat agacctacca agattgcagg tgagaagaag aattattatg
     4741 tattttacaa aattgagtaa atttatcagt tgtattaaat aatttagttt agttttgggg
     4801 ggattaatac aatgtgtgag aatttacttg ataatatgta tattgaaaag agaaaagaag
     4861 aatat
//
LOCUS       DAGQVA010000136         4841 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.140, whole genome shotgun sequence.
ACCESSION   DAGQVA010000136 DAGQVA010000000
VERSION     DAGQVA010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4841
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.140"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            306..683
                     /locus_tag="MIV85_003655"
     CDS             306..683
                     /locus_tag="MIV85_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2962951.1"
                     /translation="MKEEILIEKLLRVELIVMEYLWKKDTLMPKKKIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            788..1162
                     /locus_tag="MIV85_003656"
                     /pseudo
     CDS             788..1162
                     /locus_tag="MIV85_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            1774..2466
                     /locus_tag="MIV85_003657"
     CDS             1774..2466
                     /locus_tag="MIV85_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2962952.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            2662..4722
                     /locus_tag="MIV85_003658"
     CDS             2662..4722
                     /locus_tag="MIV85_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2962953.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
BASE COUNT         2054 a          411 c          770 g         1606 t
ORIGIN      
        1 tttagtaact tgttaacata acttataatt tattttatag gcattagcct atatagcttt
       61 gtgctactaa atttctttga ttctagcgat ttagtgctat tctacaacta aaataataca
      121 atagagctat ttattgtttg gtagcattgt ttgcaaatta aacaaattta tatatatgaa
      181 tattatttta cgtttaaaaa aacagactaa atatgtagaa tatttggtaa aacttacctc
      241 tagtttttgt cttaaaaagc tcctattatt aatttaagtt agaagaatta aggaagtgac
      301 ataaattgaa agaagaaata ttaatagaaa aattattaag agtagaatta atagtaatgg
      361 agtatttatg gaaaaaagac actctaatgc ctaaaaaaaa aattgtaaaa gaaataaaac
      421 agatttatgg atggcataaa agtacaataa aaatactact aaaaaggcta gttgataaaa
      481 ggtatttggc tagatatatt ataaattttc aatcttatta taaaataata atagataata
      541 aagaatatta tacttttaag aaaaaggtac taaaatctag taaaagcata aaaataatgc
      601 attcacttac cactatacat aaaaatgtaa gtaaagagaa gttagaccta ttagatgagt
      661 attatagaaa cttaaaagaa tgatatagta aaaatcgaat gtaattattt accttaattc
      721 ctttgtttgt aaaactttat tgatatagaa tttgacatat acataaattg gtaaagggat
      781 gtatactatg aaaattagta aattaccaga agcggaatta aaagttatga gatatatttg
      841 ggaatcagaa aaggtattaa taccaagaga aatcaccaag tctatggaac aaaaatatga
      901 atggaaagat acaactatat ttacagtatt aaaaagatta ctaaagaaga gagtttttag
      961 aagcggagaa aatagataag tgtacacact ataatgtatt agtaaaaaaa aataatatca
     1021 gagattttaa acaaaagaat ttttaaagaa tacacataaa aattcaatat taagtttaat
     1081 gtcagcacta tgtagtaagg atgatgaagt agatggtgat attttaaatt tattagaaga
     1141 atattttaag aatttgaaat aagaaaatga caaattgata cataataaat aaaatgaagg
     1201 tatgaaatta taactttttc taccttcatt ttgtttatta ttctgaacat gttaagaaaa
     1261 tgaaataagt ttgtatttta gttatataaa ttttaataga atatgtacag tatatagtag
     1321 atagaatgta taaaaataga atttaaataa gtagctatta ttgcagtgaa atgaatgttt
     1381 ctaagtatat ttgggtggaa gaatggtgga agaaaattag tgaaatgtaa ttcttccacc
     1441 attcttccac ccaaaaaata aaaactgttc aataagaatt aatatacatc aattcagctg
     1501 aatgcaatca aaatacttaa atgaaagtaa tctgaaaaca acataattca aatcaattta
     1561 ttcaaataaa cctcaattta tcttaaatct taagaaatat ttaagaatta ggataatatt
     1621 ttcttaagat ttatatttta ttatatagtt ataagggaaa gttacaaaaa tgtaagccaa
     1681 agtaatataa caatttagtc attgttgaga aagggagtga aagatattgt ataatataga
     1741 taagtattat tatacaatag aggaagtgaa aatatgtaca atatattagt agtagacgat
     1801 gataaagaaa ttgttgattc gatagaaata tatcttaaat cagaaggatt taaaatatat
     1861 aaagcatatg atggaatgaa agctttggaa ataataacag agaatgacat tcatctaata
     1921 ctaatggata taatgatgcc taaattagat ggaatcaaag caactgtaaa aatacgagaa
     1981 gaaagaaata ttccaataat tttaatttca gcaaaaagtg aagatacaga taaaataata
     2041 ggattaaata ttggagctga tgattatata acaaagccat ttaatctatt agagcttata
     2101 gctagggtta aatcaaactt aagacgatat gtaactttag gtaattatga agatacatgt
     2161 aaagaaattc taaaaagtgg agctttggag ttaaatacac taacaaaaga agttaaaatt
     2221 gatggtgaaa acataaaaat gactccaatt gagtataaaa taattgaact tcttttagaa
     2281 aataaaggac gagttttctc aatagatgag atatacgaaa aagtatggaa tgaggaaagt
     2341 tttaattcag aaaatacagt agcagtacat atcagacgaa taagagaaaa gattgaaata
     2401 aatccaaaag aaccaagatt tttaaaggtg gtgtggggag ttggttataa gattgaaaaa
     2461 ttttagtgga aaaattataa aagaaaagag tttaatattt aattgcattt tgattttagt
     2521 catttttaca tttacacaaa tgttaggaat tttaatatgt tttaattttt tctctgagag
     2581 tttaatttac tctatgggga ttatgctttt cttaaacttt attttatata aaatactgac
     2641 aatgtagatg aggtgggcaa cttggagaaa tatagagtat taaagttagt ttcattaatc
     2701 ataatatcta tctcatttcc attaactata ttgttggtga caataggact tgctgagcct
     2761 aaatacaata tacaaaaaac ttctacaaag agtgggattt ttgatatatc tgatgatttt
     2821 tatgatagta atatatttga cgaaggaaca atggcaagtc tattacccaa gtttaagcta
     2881 tctgtaggtg gtaaattaac tagtaaagaa aaaggtaaat tccaacaaga aggtaaaagt
     2941 atagatttaa gtagtagtga ttctgagtat gataaaatca tgattaatga acaagcttct
     3001 gaagaatatt taagttatct aaaaaatata aaagtgtatg ttattaatac atacacagga
     3061 gtattttata caaatacgtc atatgctagt ttatatgatt ttaaacaaaa aactaagagc
     3121 tattgtaatg tagagataat aaataagata ggaaagagct catatattaa aacaataaat
     3181 ggagaaaaat ttgaactgaa taatctgagt ctggaactaa atgaagtaga tgaaggtttt
     3241 gaggcatatg tatcttttcc agaagagcca actatagaag atggaatagt atatactaat
     3301 tttcaaatat ttaaacaagc tacagaaaaa gtaagattat tttttgtagc tagtttaagt
     3361 ttagcaatta tatgtttatt atctataatt ttatatatca aaataaaagg tgaagtttta
     3421 aaaagaaata atgtattttt actaatatac agtaagatac ctatggaatt taatgtaata
     3481 ttagtatcta tttcaattgc aattttaact atatatgctc ttgctgtatc ttatcatatt
     3541 gatgtaattg cattagtttc tttatcttta ctgatagtat caaataatat attttttata
     3601 aatgtgcaat tgagctattt agaaaataaa atgtgtatat ttaagacaag tattatagta
     3661 agagtgattt tatggttaat aaaaactgta agggaggtca gtaacgctat aaagaaagta
     3721 tctttagcaa ggaaagttat tgttatagtg ataatatctt tagctttaat catggcaatt
     3781 agcactcgaa gtataggtat gggattactg ttttctatat gtattttttt aggatttaca
     3841 atatatataa ctaaaagact ttcatatctt agttacgtaa tagaaggtac agaaagaata
     3901 aaaaagggag aattagatta taagataaaa attactggga atgataattt tacgtcttta
     3961 gctgaaaata taaataatat tggagaaggt cttgatagag ctatagaaga gcaagtaaaa
     4021 agtgaaagaa tgaagtctga ccttataaca aatgtatctc atgatttgaa aactccactt
     4081 acttctataa taaattatgt agatttaatt aaaaaagaag aatcaataca accagagtat
     4141 ataaatgatt atataaatgt acttgagtca aagtcaaaaa gactaaaatt attgatagaa
     4201 gatttatttg aagcgagtag agtaagtagt ggcaatatag aattacaaat tagcaagatt
     4261 gatttagtgc aactattaag acaaagtata ggtgaacttg aagaaaaatt atctaaaaat
     4321 aatttatatt taaaattaaa tgttccaaat gataaggtgt atatatgggc agatggaaga
     4381 agaatgtata gagtatttga aaatctttta tctaatatag caaaatattc cttagaagaa
     4441 actagagtct atattgatgt atatgactat ggtgaaaatg taaaggtaac tatgaaaaat
     4501 atatcttctt atgaattaaa ttttgaccca agtgagatta tggaaagatt taaaagagct
     4561 gatgaatcaa ggaatactga aggaagtgga ttagggcttg ctattgcaag agatttagta
     4621 gctttacaag gtggaaaatt ttatatagaa atagatggag atttatttaa agcaaattta
     4681 gagtttcaaa aatatgaaga agaaataaca aatatggaat gagatagtat ttaagtatat
     4741 atattttttt tactgtcgaa agcttttatt ataatatatt agaatattta cagtagagaa
     4801 tgaagagtaa aaacagagta actttaagtc actctgtttt t
//
LOCUS       DAGQVA010000137         4829 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.141, whole genome shotgun sequence.
ACCESSION   DAGQVA010000137 DAGQVA010000000
VERSION     DAGQVA010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.141"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            243..749
                     /locus_tag="MIV85_003659"
     CDS             243..749
                     /locus_tag="MIV85_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBY2962954.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTIAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            1162..1830
                     /locus_tag="MIV85_003660"
     CDS             1162..1830
                     /locus_tag="MIV85_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962955.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSGKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            1989..2495
                     /locus_tag="MIV85_003661"
     CDS             1989..2495
                     /locus_tag="MIV85_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBY2962956.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            2623..3639
                     /locus_tag="MIV85_003662"
     CDS             2623..3639
                     /locus_tag="MIV85_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBY2962957.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            3993..4697
                     /locus_tag="MIV85_003663"
     CDS             3993..4697
                     /locus_tag="MIV85_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBY2962958.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
BASE COUNT         2040 a          419 c          811 g         1559 t
ORIGIN      
        1 tttttttatt gtatattgct ttaggtttaa aaatatatta tatactttat aatcaatata
       61 ttttatctat attttacact tataaaatat gaaaactact tattgcgaaa gtaattgatt
      121 tgttgtatta taatttacat gaattatgta ggacaatcaa aagtcagtat tataagagta
      181 catatattca aatttttaac aattaattta tataattaaa aaatgaaggg taggatgaag
      241 tcatgggttt tagagaagta aaaattgagg aattacagtt taatccattt actaagattg
      301 gcaaagaatg gttacttata acagctggtg attcagaaaa gtttaacaca atgactgcta
      361 gctggggtgg tgttggagtc tattggggta aaaatgttgt tacaacttac ataagaccac
      421 agagatatac aaaagaattt gtagatagta atgatacatt tacaattgcc ttctttgatg
      481 aaacgtatag agaagcttta aatatttgtg gcactatttc tggtagagat ataaataaaa
      541 tagaaaaagc aggacttaca ccatattttg tggatgatac ggtagctttt gaagaagcta
      601 atatgattat agtatgtaaa aagctatatc atggtaatat gccaccagaa aactttgatg
      661 ctaaagaaaa tgataaaaaa tggtatccag agaaagacta tcatactatg tacatttcag
      721 aaattataaa agttcttgta aaagaataat tataataaaa aatatatgaa aagaacttat
      781 tataagtaaa tgactgtgct ttcttatctg atatctaagt agatgctact aactaaataa
      841 atattaattt taaataaata ctattataaa aaagatgaac tatatttact atagttcatc
      901 tttttattta tataagcact tatataagta gagatttatt tgaataaaag tatttatttg
      961 aaatatttga gtatacttta taagtatttt tatgctaact agaaacactt aatttatggc
     1021 atttgtactt gatttatttt aatgtaaata atttcaaagt taattttatt caatatagta
     1081 ctataaaagt ataaataaca tttaataaaa atatatatta tattaggtat tttaaataaa
     1141 ttttttaaag ggtgattttt tatggaaaat ataactagtt attttacaac aatactatgt
     1201 gtatttatat gcttatcatc tgtatttata tttactcaac tagctagagt atttattaat
     1261 aagaagaaga ttaatcaaaa aattaaatca agaaacggat ttaggtatga tagagatttt
     1321 attgaagcca gaagagaaga aatacatata aaggataaca ataataataa aaataagagt
     1381 aacaataaga aattaaagga agaaaaagta tttaaatacg ataatggtga tttatataaa
     1441 ggtgagtttg ttgatggaaa gaaaaatgga tttggaatat atattttttc aggtaaggaa
     1501 aagtatgaag gattatggaa agatgacaag atgcatggaa taggaaaata tacttataga
     1561 gatggttcaa tatatacagg tgaatttaaa tacggattaa aaaatggttt gggaaaatta
     1621 acatatccca ataatgacat ttataaggga tattttttag ataataagaa aaatggtaag
     1681 ggtgtattat ataaaaatga tggaaataaa caagcaggaa tatgggaaga tgatgaacaa
     1741 tgtaaaagtt tagattttaa agatttaaat aataataaaa taaataatgt ttatcaaaat
     1801 agattaaata acaataaatt aaaagtttaa ttattctaat aaaaaaatct ttatttatga
     1861 tggaatatag gatatatcta tgttgtaatt tgtaaaatct tcctatatca tataaaatta
     1921 agtattgatt agtctattac ataaatatag aatataaata tatccattta ataataagga
     1981 gaagagatat gaaagagtat gtagttgtgg atttagaaac tacaggatta gatccatata
     2041 aaggttgtga aataatagaa ataggaataa cagaaataaa aaatgaacaa attgtaaaaa
     2101 actattcaag gttgataaaa cctaagggga taatttcttc atttataaca gaattgacac
     2161 atataagtaa tgaaatggta gaaaatgaag aaccactaga attagtttta cctagattta
     2221 gaaaatacat aggtgataga actataattg cacacaatgc gaaatttgat ttaaaatttt
     2281 taaattacta tcttagaatg ttagatttag aaccaataaa caattatata tgtacagtag
     2341 agttattaaa aaaatgtaaa agttataaag gaaaaaacaa gaaacttgaa acagcttgtg
     2401 cttattacaa catagagaat ataaatgctc atagagctga cagtgataca ttagcaactg
     2461 caaaactatt tttgaaaata aaagatgaat attaattata aatatagaga aaattagtga
     2521 aaatatcctt tataaaattg acccttaagc ttacaatttt gttctttgat ttattttgta
     2581 gaacaatgta taatgtacct tatatgaaga agggagacta aaatgggtta ttacaatgat
     2641 aatgataata ataaaataag acgtaaaaaa attagtaaca acaaagatag taataaaaaa
     2701 tctaaacatt cttatacttc ggcaaataaa aaaaataaaa gtcctaatac aagttccagt
     2761 aaaagaatga gtgaaaaagt agattcacag aatcttataa aaagagatag agatagtttt
     2821 acaagagata atgtaagacc tttaaataca gattacaatc aaagagaaag aagaagagtc
     2881 gagtataaac aaagagagaa aaaattaaaa agtaaaaaaa gaaaaaaaca aaaaaggatt
     2941 agaatagtta gggcattatt atctattatg ttagttgcac taattatatt ttcagtggca
     3001 ggtgcaatat ttacagtttc agctataaaa gggtcaccag aagttactaa aaagttaatt
     3061 aggtctaaat atataagtag tgaggttgta agtataaaac aaatgccaaa tgatttaaaa
     3121 catgcaatag tttccataga agatgagaga ttttataagc ataaaggagt agatgttatt
     3181 tctctagtta ggtcagtatt aaacaatgtg tttacagata caacacaagg tgcaagtact
     3241 atagatatgc aagtttcaaa aaacctgctt actagtaatg ataaaactat gaagcggaaa
     3301 ataagggata tgtataatgc taagcagatg aataagatta tgactaagga tgaaattctt
     3361 gaagcatatt taaataatat gtatctaggt aaaaatgcat atggagctgc aaagggagct
     3421 gaagtctact ttggtaaaaa agttagtgaa ttaaatttag ctgagtgtgc tatgttagct
     3481 ggtatgacaa ataatcctgc aaggtatatt gaccatggag aggctaagaa gagacaagtg
     3541 attgtactgt ataagatgca tcagcttggt tatataactg ataaggagta tagaatagca
     3601 aaagctgatg acactccatt taaatcagaa attgattaaa attgtaagaa tatagtattt
     3661 tcaatagttt aaacaaacaa aaatgtaata aaaaaggtga tttgccaccc atttgccacc
     3721 ataattataa tctaatggca aattgtttta atgtacaaac tagataatag aatattgtct
     3781 taaatgctat attatgctaa aatttaattg tattttgtaa attaaaaaac ttataattta
     3841 gttttctagg gttccgcatt ttataatggt caggtccaag agaaaacgcg caattgttgt
     3901 gtacacggaa ggataaaagc ctgggagata tttaagaata tttctatagg cttttttatt
     3961 tttacatatt ttaaatttga ggaggttttc taatgaaaaa atttgttatt gaggatgcat
     4021 tttggaatct atttcctagt gcaaaaattg gagttgttat ttgtaatgat atagataact
     4081 ctataaaaga tgaagactat aagaaaataa ttttgaaggg agaagaagaa gcattaaaat
     4141 acttggagga ctcagaattt agcaacaacc aagtgattaa agtatggaga gaagcattta
     4201 aaaaatttaa aacgaaaaaa ggagcaaggt cttctattga agcattatta aaaagagttc
     4261 ataatggaaa taatatagga actattaacc ctttagtgga tatctacaat tttatctcat
     4321 taaaatatgc attaccttgt ggaggggagg atatagataa atttatagga gatattaggc
     4381 taactagagc aattggtaat gaggagttta tcccactagg gacagatgaa aattcatttc
     4441 catatgaagg agaaataatt tataaagatg atggtggagc aatttgtaga tgttggaatt
     4501 ggcgtgaagc agtgagaaca atgcttactg aagatactaa caatgccttt ttatgcattg
     4561 aattagtaga tgaaagtaga tttaaagaat ttgaaaatgc tttaaatgaa ttagctaaaa
     4621 tagttcaaga aaaattgggt gggaattgta aaatttcaat tttagatatt gataataaag
     4681 aggtatcagt ggattaatat ggaggtgctg ttgtaatgga ctattctagt tataaagata
     4741 cttatattta gggtaagaag gtctatttta gatataacga ttatcaaagg atataatata
     4801 gaaaataaaa atgtagaata taaaaagcc
//
LOCUS       DAGQVA010000138         4675 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.142, whole genome shotgun sequence.
ACCESSION   DAGQVA010000138 DAGQVA010000000
VERSION     DAGQVA010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.142"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(1012..1209)
                     /locus_tag="MIV85_003664"
     CDS             complement(1012..1209)
                     /locus_tag="MIV85_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962959.1"
                     /translation="MQIKIMELLDKKGKTRYWLAKEIGIKQQSLNKIASNETVSIRFD
                     ILEKICTTLECTPNDVLGWDK"
     gene            1342..1650
                     /locus_tag="MIV85_003665"
     CDS             1342..1650
                     /locus_tag="MIV85_003665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962960.1"
                     /translation="MINKNILKEQQLNKIKVLKNKNDKNIKNNIFKMFNSDMEEMKSI
                     IKNELFFENIYQDELEFHMNKIKNIENIADKFYVQFMISGEEGFEITCLRTALANRSI
                     "
     gene            2323..2943
                     /locus_tag="MIV85_003666"
     CDS             2323..2943
                     /locus_tag="MIV85_003666"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962961.1"
                     /translation="MNKKVEKPFVYKREYDLTKYDTKVLQKYNLEQAIYIYVGSSCAY
                     NMRARSSKWRYHIRKNNGSICYTIRNFIHNLELFYKRELELPDNIIDDKLYYSNVVEF
                     EEFETLEKAREIESTIISQYQFLDSVNYMLKQKIILLSNNDSALCMVKNGNQVSLKIK
                     NKYIEKYKNKPIMRYHIDCQFNTDGSVKSITQEFEPILELSNKKIL"
     gene            3162..>4675
                     /locus_tag="MIV85_003667"
     CDS             3162..>4675
                     /locus_tag="MIV85_003667"
                     /inference="COORDINATES: protein motif:HMM:NF020291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBY2962962.1"
                     /translation="MKGKDIQEKLITYFKFIFPKLETDEKYRAYMLVENSKTNFTRTF
                     KLNTYHELVEVVNKYNSKANIYISTCLYDNTKDKTKENILSKSVIVVDVDNADFDISE
                     IYKLAKINQVFIHLVVRSGRGWHLYFKLDKEYSNVKQLEKASKHLCELFGGDKNSLDV
                     GHVYRVPFTKNLKYDNTWSSIVNTINKTFPHTLDKLINHVPIKSSLSGNTELQVDNVE
                     QLSCFKNLVKYGISKGFRNKAMIAISNTCKYIGLSEVEALQYAYEFNSNCEVPQRKTE
                     VVKVVKSIYNNSSLIKPCKDNLNKKLCNSHCMGRLITVDDVLNKIDENIDNDIQVAFS
                     NKLIGNIKTYINKDGKKEKGTMLSVLSGAEILIISELKTFRNEIYSVDDLIDTTNLSK
                     PTIIKSLKRLEEFNIINSTKQHFNRSSKPTTIYFYNDECEQKYKEIHSIGRGLFIIRR
                     NKLITDNDMKVYIALKYLINKRMSTTQNDIELISGVTRNNINRSIKNLIEQDLL"
BASE COUNT         1914 a          468 c          709 g         1584 t
ORIGIN      
        1 aaaaaaacaa gttcaaagta caaatggaac atttaatatt tatacattaa aattatagaa
       61 aataaaaagc acttacaatt aatttgtagg tgctttttta aaacaagtta aaaatcaaaa
      121 atagtattag gaggcattgg aaatgctaga ttctaaaata gaaaagtaaa aaattgatgc
      181 atagtccaaa atacttcaaa ctattgaaat atacatattt tttgatgaga aaagtaaaaa
      241 attgatgcac tatctaaact tatctatatc tcttcttcct ttgttaggga ttaccttagt
      301 tacaatacag aggatatgct tatattaagt gagagtaata acccgtgttt aatatagtta
      361 ctagaattat agttactata gtttcgtatc tgtggcacaa taatagaata actaaaataa
      421 tgttagatgt ttacatgtac tttagttagg aactcgaatt ttacgagttg taatatctaa
      481 cactctaaat aatagctata gatattaaac gtgtacttga aacggacact tgaatatgtt
      541 tagaccactt gtgggagaaa gtataattgc cacgtgtggc taacacgcac gcgttagata
      601 taaattagtt aaatcctaat atgtggtata ccacttgaat atacattgtt gtgcaatatt
      661 gcaaatagta atagtcccaa caagttgggg aagtaacaaa tgaattttta cgttggttaa
      721 ggtgtaccca ttttggatac accctctata atttagttat gcaatatatg tttatcccaa
      781 atagtgatat taaaatactt gttttattct aatttaacaa caaaaccctt gtatgctagt
      841 tattgcaatg tttacattag ttttttatat gtcagtaagt taagacataa aactaagtat
      901 tttatgccat atttatatat atattagtag ttgcaatgtt tttataccta tcataggtat
      961 tgatttaaag ttaatttgtc agttacatgt cagtatattt gccataatag attatttatc
     1021 ccaacccaat acgtcatttg gagtacattc taaagttgta caaatttttt ctaatatatc
     1081 aaatcttatg gatacagttt catttgatgc tatcttattt aaactttgtt gtttaatacc
     1141 tatttcttta gccaaccaat atctcgtttt acctttttta tctaaaagct ccattatctt
     1201 aatttgcata aaatcctcct ccttaaatta ttgttaagag taagtatagt ttagaaggtt
     1261 ctgtttaaca ataatgtcta ttgacggtac ttacgctaca atggtattat gtttatatat
     1321 ttttgaagaa gggataaaaa gatgattaat aaaaacattt tgaaagaaca gcaactaaac
     1381 aaaattaaag tattaaaaaa taagaatgat aaaaatataa aaaacaatat atttaaaatg
     1441 tttaatagtg atatggagga aatgaaaagc attattaaaa atgagttgtt ttttgaaaat
     1501 atctatcaag atgaattgga atttcatatg aataaaatta agaacataga aaatatagca
     1561 gataagtttt atgtgcaatt tatgataagt ggagaagaag gttttgaaat aacatgtctg
     1621 agaacagcac tagcaaatag gagtatatag taaaggttta tataatatga tgacctcata
     1681 caagcctgta agagccgttt aaaagctgtc ttagtgtaat taatccttga aaatttaaaa
     1741 tacgtttaaa tggcttgtta aatatggtgg tattactatt aaatataggg ggtagttaca
     1801 tagttacatg ttgttttaaa aaataaattt aactatagtt ctttcacttc tacattacaa
     1861 aaaaataaat tgagtgtgta tgtttttagg tcaaaatgat gtttaaatat tgaaaaatag
     1921 ggatatggtg tatgtaaaat ttagaatagt gtatgtaatt ttaggcataa aaatatgtga
     1981 ttaaacctta aaaatcagga atatagtgta tgttaaaaaa gattgacata cgtgttaaaa
     2041 aaagttataa ttaaggatta gatatatatt gacatgattt attttctatg ttattatatg
     2101 tttagattaa aacatatcaa attaccatat ctatttatat attgactatt tgttaatatg
     2161 taacatgttt gtatttcaat gtaaatacaa tcttttatat cctgtgtgag ggtataccat
     2221 taaaagtatc ttatattcaa caaattaaaa aaatttaata ggaggtgtag tgtaaaagga
     2281 tttttagtta ctaagtttaa ataaaaaata ggaggacact tattgaataa aaaagtagaa
     2341 aaaccattcg tgtacaagag ggaatatgac ttaacaaaat atgatactaa agttctacaa
     2401 aagtataatt tagaacaagc tatatatatt tatgttggca gtagctgtgc atataacatg
     2461 agagctagaa gtagtaaatg gaggtatcat ataagaaaaa ataatggttc tatatgctat
     2521 accattagaa acttcataca taacttagaa ttgttttata aaagggaatt agagttgcca
     2581 gataacatta ttgatgataa gttatattat agtaatgtag ttgagtttga agaatttgaa
     2641 acattggaaa aagctaggga gatagaaagt actattataa gtcaatatca atttttagat
     2701 tctgtaaatt atatgttaaa acaaaaaata atcttgttaa gtaataatga tagtgcatta
     2761 tgtatggtta aaaatggaaa tcaagtatct ttaaaaataa aaaataaata catagaaaaa
     2821 tataagaaca agccaataat gagataccat atcgattgtc aatttaatac agatggaagt
     2881 gtcaaaagta ttacacagga atttgaaccc atattagaat taagcaataa aaaaatactc
     2941 taagccgaca agcagagtat ttagtataaa aaagatttat ttcaacaaca acactattga
     3001 tatagtgtga atgagttagc gttcattcaa gttgtttatt gactatattt aaaattacat
     3061 atattaataa gattttaaac ttatgataat ttaatgtaat ttaatgatat tattaattag
     3121 acattatgtc aagagtgttg ttctgaagaa aggagcaaca ggtgaaagga aaagatatac
     3181 aagaaaaatt gataacgtac tttaaattta tatttccaaa acttgaaact gatgaaaagt
     3241 atagagcata tatgcttgta gaaaattcaa agactaactt tacaagaaca tttaaactta
     3301 acacttatca tgagttagta gaagttgtca ataaatataa ctcaaaggca aatatataca
     3361 tatcaacttg tttatatgat aatacaaaag acaaaacaaa agagaatata ctatcaaaat
     3421 cagtaattgt agtagatgta gacaatgctg attttgacat atcagaaata tataaattgg
     3481 ctaaaataaa tcaagtattt atacatttag tagtaagaag tggacgaggt tggcacttat
     3541 actttaagtt agataaggaa tattcaaatg taaaacaatt agagaaggct tctaaacact
     3601 tatgcgaatt atttggtggt gacaaaaatt cattagatgt tggacatgta tatagagtcc
     3661 catttactaa aaatttaaag tatgataata cttggtcaag tattgtaaat actattaata
     3721 aaacatttcc acatacactt gataaattaa taaatcatgt accaattaaa tcatcactta
     3781 gtggaaacac agaattacaa gtggacaatg tagaacaatt aagttgtttt aaaaatcttg
     3841 taaaatatgg gataagtaaa gggtttagga ataaagctat gattgctata tcaaacacat
     3901 gtaaatatat tggtttaagt gaagttgaag cattgcaata tgcttatgaa tttaattcaa
     3961 attgtgaagt tccacaacgt aagactgaag tagttaaggt tgtaaaaagt atatataata
     4021 attctagttt aattaaacca tgtaaagata atttgaataa aaaattatgt aatagtcatt
     4081 gtatgggaag gttgattact gttgatgatg tacttaataa gattgatgaa aatatagata
     4141 atgatataca agttgcattt agtaataagt taattggtaa cattaaaact tatattaata
     4201 aagacggaaa aaaggagaag ggaactatgt taagtgtttt gagtggtgct gaaatattaa
     4261 taatatcgga gctaaaaaca tttagaaatg aaatttattc agttgatgac ttgatagata
     4321 caactaattt aagtaaacca acaataatta aatcattaaa aagacttgaa gaatttaata
     4381 taatcaacag tactaaacaa cattttaata gaagttcaaa acctacaact atatattttt
     4441 ataatgatga atgtgaacaa aagtataaag aaatacattc aatcggtaga ggtttattta
     4501 taattagacg caataaatta ataactgata atgatatgaa ggtttatata gcactaaaat
     4561 atcttatcaa taaaagaatg agtacaacac aaaatgatat tgaacttatt agtggggtaa
     4621 ctagaaataa tatcaatagg tctattaaaa acttgataga acaagattta ttaag
//
LOCUS       DAGQVA010000139         4675 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.143, whole genome shotgun sequence.
ACCESSION   DAGQVA010000139 DAGQVA010000000
VERSION     DAGQVA010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.143"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..609
                     /locus_tag="MIV85_003668"
     CDS             <1..609
                     /locus_tag="MIV85_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008819588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore surface glycoprotein BclB"
                     /protein_id="HBY2962963.1"
                     /translation="PTGATGATGVTGATGPTGPTGATGATGATGASAIIPFASGIPLS
                     LTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTNFAFSMPRDGTITSISA
                     YFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTLAPPLTGILSVGSISSGI
                     VTGLNIAATAQTRFLLVFTATASGLSLVNTVAGYASAGIAIN"
     gene            778..1539
                     /locus_tag="MIV85_003669"
     CDS             778..1539
                     /locus_tag="MIV85_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBY2962964.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            1848..2126
                     /locus_tag="MIV85_003670"
     CDS             1848..2126
                     /locus_tag="MIV85_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962965.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            2419..2994
                     /locus_tag="MIV85_003671"
     CDS             2419..2994
                     /locus_tag="MIV85_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBY2962966.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(3100..3933)
                     /locus_tag="MIV85_003672"
     CDS             complement(3100..3933)
                     /locus_tag="MIV85_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBY2962967.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(4001..4630)
                     /locus_tag="MIV85_003673"
     CDS             complement(4001..4630)
                     /locus_tag="MIV85_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBY2962968.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
BASE COUNT         1727 a          604 c          755 g         1589 t
ORIGIN      
        1 ccaacaggag caacaggggc aacaggagtt acaggagcaa caggcccaac aggcccaaca
       61 ggagcaacag gagcaacagg agcaacaggt gctagtgcaa taataccttt tgcatcaggt
      121 ataccactat cacttacaac tatagctgga ggattagtag gtacacctgg atttgttgga
      181 tttggtagtt cggctccagg attaagtata gttggtggag taatagacct tacaaacgca
      241 gcaggaacat tgactaactt tgcattttca atgccaagag atggaacaat aacatctatt
      301 tcagcatact tcagtacaac agcagcactt tcacttgttg gttcaacaat tacaattaca
      361 gcaacacttt accaatctac tgcaccaaat aactcattta cagctgtacc aggagcgaca
      421 gttacactag ctccaccact tacaggtata ttatcagttg gttcaatttc tagtggaatt
      481 gtaacaggat taaatatagc agcaacagca caaactcgat tcttactagt atttactgca
      541 acagcttcag gtctttcatt agttaatact gtagcaggat atgcaagtgc aggaattgca
      601 ataaattaga ttagataaga aaaggcttct aatatcgtat tgatattagg agctttttta
      661 agaatgattg atgaacatag ttttaatatt aattagtgcg catattataa aatactatta
      721 tataatataa aataataaca ttaaattgga aatatagaat tatctagggg tgatactatg
      781 aaaaataaga ttgaaatatc aatgaacaac tttgtaaaaa attatcataa atcaaataat
      841 ataactacaa agtggcaaga acttttgttt gcttatgcat ctgctgaaga tgatatgttt
      901 cagaagctaa aaagtgttgt aggaacatct catgctatgc caaaagattt tctggaaaat
      961 ggaaaaacta taattacata ttttatacct tttgatgaaa gtgtaaataa tagtaatatt
     1021 ggagggtttg aatgttctga aatatgggca agagcgtaca tagaaactaa tatgttgatt
     1081 tcaaatttaa atgatttctt atgtgaagaa ctagagaaga taggggctaa ttcatatgct
     1141 attcctgggt cgtataattt tgacagtgaa aaattggtaa gtgactggtc acaaagacat
     1201 gtagcattca tagcaggtct tggaactttt ggtttaaata atatgcttat tacagaaaaa
     1261 gggtgttgtg gaagaatagg aagcataatc acaagtttag aattagagcc aactaaaaga
     1321 ccagaaaatg aatactgctt gtataaacat aataatagtt gcaaaaaatg tgtcaataaa
     1381 tgcgtgaaag aagctttaaa agaagatgga tttaatagga ataagtgtta tgaaatgtgt
     1441 atgataaatg aaaaaaaata cacttatata ggtggatgtg atatttgtgg aaagtgtata
     1501 gttggagttc cttgttcagt aataaaccca tcaagataat ggatttaagt tgactaataa
     1561 ttttaaagat agtttataat gaaaaaattt tagttatcaa aataaatata atataaaaac
     1621 taaataaatg tgtttaaaaa atggataaat aatttgtgtt gattgacaac cagttatact
     1681 gttgatagac ttatatgtat cgctgtgata tataaggagg gttgagattt tatgtttgat
     1741 ttaatcttta tttttgcata gcaagggcta ttgcaactat gaaatttaat atataaatag
     1801 ccctttgcta ttcctaatga aaaattacta tttaatagga gagcaaaatg agctataaaa
     1861 aagcaataca tatattacca gaagaattac ttgaattaat acaggaatat gtagatggtg
     1921 aatgtatcta tattcctaga aaatctaata ataaaaaaga atggggaagt aatacaccta
     1981 ctcgtgagga gttgtcaatt agaaatatgc agatttacga agactatcaa gttggatatg
     2041 atttgcaata tttatcggaa aagtattatt tatctttgaa aagtatccaa agaattgtat
     2101 tacaagaaaa aagaaaagat atctaaggat gagccagtat agttttataa ttatactggc
     2161 tcattttctt ttgataaaag tgtttgaggt atagtttctt ttaagtggat gatataattt
     2221 aagtaatttc aataacttat acagtagcta acaaagctgg ttgtaaagta tctaataaga
     2281 agtagtagct ttttatatgt ttgaaattaa aatttattaa aattaggagg tcttgttttg
     2341 aaaaaaatac ttgattatat tccacctttt cataactttc tattaattta gtaatcttat
     2401 agaaaggaaa ttgcatttat gaaaaaaatt acttgggagg tggaatatat ctcccagtta
     2461 cctgtaatta ggtattgtaa aaaatgtgga aaaaagactg aatatatttg ttcaggttta
     2521 tttagggtta atgctcaaca taaatatttg gatatatggt taatatacaa gtgttcaaat
     2581 tgtgattcaa catggaactc aactatatat tctcgtgtta atccaaaaag cttaaatcca
     2641 gaaatactag aacaattcca tacaaatgat tataatcttg ttaagcaata tgctatgaat
     2701 atggaacttt tacatagaaa tggagcagaa gttggtattc cagagtataa aatagtagga
     2761 caagaaatta atattaatga ccttacacaa gttcatatta ttagtaaata tccatgtcag
     2821 ttaaaggtat caacattatt acgtgagaaa ctaggtttat ctaggaaggt atttgacgaa
     2881 atgttggatt gtgggattat tagaagtaac tcaggagttg atttaaagaa aggtaaatta
     2941 aattatgaaa ttatgttaga tataggcaag gagaagcaaa agtcttcaaa ttgattagaa
     3001 taactaactt aatatatttt caggaacatc atttaaaaaa atagtgactt taaaaaattt
     3061 aaagccacta ttttttaata tgttttatct atataactat tatttttcta ggttttttaa
     3121 tatttcgtaa tagtgtgttg tggctatttc acttgactcg ccttttttac aaaaagataa
     3181 tttagatagt tttggaacta cacgttcaac gacaatttta ttacctatca ttttagattc
     3241 aagtatcttc aatgcttcta aaaatctctt atcctttttt gcacgattat aaaatgataa
     3301 aacgtagaca taaaggaata ggttataatt acggaaagga tattcaactt gcataaataa
     3361 tgtgccaatt ccatagtgac aagggccgat tggtttttta atagtccaat ggtcaagtag
     3421 aaaatctaca gctttgtcaa gttttgattc tttatttaga taattactaa aacggaatgc
     3481 atttaatata ttaagagttg gtagtggatt tgagtattca gtttctggac ctcgaccaaa
     3541 actaaattta ttgcaacgcc acccaccatc agtatactgt gtatctaaaa aatgttgaaa
     3601 cgttttttgc attctaatgt cagatgcata tcccatatga cagagtacgt tagcagcatt
     3661 tgcagtatga caagggtaaa tacctccatt tggatatagt ttgaaacgtc catcttctcg
     3721 ccatgtgcta aatatcaggt cagcacattc tttaagtaaa gtatcatcag ggttcacacc
     3781 taattctaat agataaagta cactatcaag agtagagaaa ggagaacctt ttattaaacg
     3841 cttatcaggt gtagtccaat agtctgcacc attatcatac ctgtgtgata atattatttc
     3901 aatatctgat aaagattgat tttctacatt cattttttac tccatttcat attatattct
     3961 attaaatcta tcaaaaactt tattataata ttatttatat ttataattga tttattttat
     4021 ttaaaattgc atttatagct gtatcaggaa caactgctaa atcttctgca ttgaagtaat
     4081 aaactatatt agaatcaaat aatatatttg aatttggagg aaattcatca tctccaaacc
     4141 aaagtataaa taccatagat gtattaccca tatatgtaaa cctataagct aaatctccca
     4201 tgtttacttt ttcagctcca attttctcca taactaactt atatttgtct atttgagatg
     4261 taaaaacttc tgaaagccta tatagagtcc tgtttaaaaa atttggataa taaacattgc
     4321 ctcctggtat ttctttaaaa gttacatatt tattagttct aggaatacct ttagcattga
     4381 ttaaatatct aactatcaag attttaagct caaagttatt gcaaaggcta ccattactat
     4441 tccaaacttc tccacttgga tagtctataa tatattgtct atcaaaaaaa ttgagtgtga
     4501 atctatttaa atcattattg aaaggtatat tacttaaatt actaattgta tgagggtcta
     4561 attctttgag tttttttcga acatagtcaa atggaacatt ataattattt tttgttatct
     4621 tttcatccat aattttttcc tccaatttaa acaattaaaa gtatatttat aaaaa
//
LOCUS       DAGQVA010000140         4437 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.145, whole genome shotgun sequence.
ACCESSION   DAGQVA010000140 DAGQVA010000000
VERSION     DAGQVA010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4437
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.145"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..1067
                     /locus_tag="MIV85_003674"
     CDS             <1..1067
                     /locus_tag="MIV85_003674"
                     /inference="COORDINATES: protein
                     motif:HMM:NF015983.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962969.1"
                     /translation="KNQIFKSNNLNFDMLSNGVAIYFCLTNRCNLFCKHCCVESSSNK
                     KDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIREDFFEIIKYIKQKLPDTKLILSTN
                     GTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRGKGVFNKVISSVNLLKDNGFSNI
                     KLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPTGRGLENKESYLIEDTVLPITIP
                     YILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDGDVYPCPSLIKDDYKMGNIFDNE
                     FVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVNIFCWHCPAILDSVKDNELELDR
                     WCSMMKHNLNTAVWGDEKVN"
     gene            1064..2080
                     /locus_tag="MIV85_003675"
     CDS             1064..2080
                     /locus_tag="MIV85_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962970.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            2136..2297
                     /locus_tag="MIV85_003676"
     CDS             2136..2297
                     /locus_tag="MIV85_003676"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962971.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            2505..>4437
                     /locus_tag="MIV85_003677"
     CDS             2505..>4437
                     /locus_tag="MIV85_003677"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBY2962972.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGI"
BASE COUNT         1877 a          390 c          710 g         1460 t
ORIGIN      
        1 acaaaaatca aatttttaaa agtaacaatt taaactttga tatgttaagc aatggtgttg
       61 caatttattt ttgtttgaca aatagatgca atttattttg taaacattgt tgtgttgaat
      121 cttcttctaa taagaaagat ttacttagta catatgattt aaaaaatatc gtagatataa
      181 tatcagtttt aaatactcct catataatta taactggtgg agaaccattg ataagagaag
      241 atttttttga aataattaaa tatataaaac aaaaattacc tgataccaaa ttaatattat
      301 ccacaaatgg aactttaata gatgaacata atgttgattt tattataact aattttgaaa
      361 aaatagatat tagtattgat ggagtagatg aaaatacttg tagtgaaaca cgaggaaaag
      421 gtgtatttaa taaagtaata agctctgtta atctgctaaa agacaatgga ttcagtaata
      481 taaagctgtc tatggtattt ggacaaaaaa attctcattt aaataaacaa tttaaagatt
      541 taaataaaaa gcttggaaca gaatttgttg aaagatattt tattccaaca ggaagaggcc
      601 tagaaaataa agaaagctat ttaattgaag atacagttct tccaattaca attccgtata
      661 ttttagataa tgaattaaaa atgtgtaaag ataaaaaaaa taaaaaaatg ggatgttgtg
      721 catgtaatgc aggaaactct caaatattta taaattatga tggagatgta tatccttgtc
      781 cttcactgat aaaggatgac tataaaatgg gaaatatatt tgacaatgaa tttgtaaaag
      841 ttataaaaga aaataaaaca agagatctaa agtctttgat taaattagaa agtatttatc
      901 catataactt tgaaaaatgt aaagattgtg atgtaaatat tttttgttgg cattgcccag
      961 cgatattaga ttcagttaag gataatgaat tggaattgga tagatggtgt agtatgatga
     1021 aacacaattt aaatacagct gtatggggag atgaaaaagt taattgaaat ttactatatt
     1081 tgtaactgaa gactgcaatt tgagatgtac atattgttat gaaggtaatg ataaaaaaaa
     1141 agaaaatatg agttatgaaa ctgctgataa aacaatagat tttatttgta ataaagaatt
     1201 agaaagtaat agtgattata caacaattgt tttacatgga ggagaaccat ttataaattt
     1261 tgatttgatt aaatatatac atagggattt agtagataga ttgagtgaca aaaagatatt
     1321 atttgatata actacaaatg gaactattat aaatgatgaa ataatagagt ttatagcaaa
     1381 gaatgtaaaa aacatatcga taagtattga tggaaaaaag aatatacatg atataaatag
     1441 aatagatgct aacggagtag gtacttatga aaaagtaatg gaaaatggaa aaagacttat
     1501 agataaaggt atatatgtta gggcaagaat gacatataac tcaaatactg ttaagtatct
     1561 ttatgagagt gtatatgata tagcaaaaca agggtttaaa aatatcgcac caatttcaga
     1621 ttttatggat aaaaattggg ataattctca tattaaaata ttaaatgaac aaattagtaa
     1681 aattatgaat attaaaaagg attatcctga tatagatata tctattttag ataaacaatt
     1741 tataaataag aaaaaaggag attgttttgg agggataaat agttatgcaa tagatactag
     1801 aggagatgta tatccatgta cagtatgtgt aggagataaa gatattttac taggaaatat
     1861 atatgatgga ttagatgata aaaaaattaa gaaccttata aaaatttata tatctaagaa
     1921 tgaagagtgt gatggatgta ctagacttga ttattgtatg tcaaccagat gtaaacttat
     1981 caataaaaag gtaacaggta aattccaaag tgcagtacca atttattgtg gattagaaag
     2041 agtttatgtg gaaacaacaa aaaaactatg tagtttataa tctagtttaa ctagttataa
     2101 taaatataaa acaaaagtaa agggggatat gtattatgat acatataaaa aaaatcgaag
     2161 aaaaaataga acttcaagat gttgaggtgc aagcagatcc atgtaaatgg tattatgata
     2221 agcatggaat aatttcacaa atagactgta tggtggattg tgcaggatca actccaaaag
     2281 gaacagtagc ttattaaaaa atactaatca gtctattaaa tatgttgaaa gtactagatg
     2341 tagtttttta caaatgaaat gtgattttct caactctagt atttttaata attaaattta
     2401 actagcacaa cgagttagtt agtatttaat gaatagtgct ctataaccta ctattttagg
     2461 ttatagagtt tttcttgtaa atatgaataa ggaggattct gattatgata aatattaaac
     2521 ttgcggtgtc atatttaaag agacaaaaag gaaaaacttt atcattaata cttagtatag
     2581 ggattgctgt tatgctagtt ttttcattaa gtgttattaa tgaatctcaa ggacaatcag
     2641 atataaatca tgcatacaaa aactcgggag attatcatgc tttttatgaa gatataaata
     2701 gtgatatagt aaaagaactt aatggtgaag aagatataaa agaattcaat gatgtactta
     2761 aatttggaga aattataagt aaagataatg gagcatctct aaatttatgc tcttacaata
     2821 aagatttttt agattctact agatataagt tagttaaagg tagagagcct agaacttcta
     2881 atgaattagt aatagaacaa aaagttttag acaaaatgga attagatgtc aaattaaatc
     2941 aaactattga ttttcagatt gttaatgagc atataaataa aaataatgaa aattctattt
     3001 atagtaaaga taagcaattt aaaatagttg gtattttaag taaatctgat gaatactatg
     3061 aaaatttaaa taaatataag gtaagagctt ttacatattc aaacaatggc aaagatattg
     3121 ttccatatga attaataact catatgggta cattaaaatt gaatacaaaa gatttagatt
     3181 ctcaaaaagt agtgaatcta gggagaaaat ataagttaac aagtaatcaa ttttatccaa
     3241 atacagaagt aagtatgtct atgtatatga aaaatatttc aaaaaaaaca acttattcaa
     3301 taaagcaaag cttactccct ttattatgtg caacattagt aatatacaat atgtttaaca
     3361 taataatact agatatgacc aagcaaattg gtttacttag agctgttgga gctagcaaga
     3421 gaaatattag acaggtattt tttattcaga gtattgtagt tttatctgta ggtatagtaa
     3481 ttggtttact tggaggtata gttttttctt acttaggtct catgatagta tatgataaaa
     3541 gtgcagaatt aactataaat acaaactcta taattgaatc tatcatcatg tcaattatag
     3601 cagttatatt agcctctgta gtaccaatat ataaagctgg aaatttatct ataattgatg
     3661 ctataaaaaa gacagataag ttaaattata ttcctaggct tttgttgtta aaatcacata
     3721 aaaaagttgt tggaattata aatgagatag cttttaaaaa tatatttagg aataaggtta
     3781 catcaataat aataataatt acgatatcac tatgtggggt tttatttata ggcagactaa
     3841 cttctacaaa attcatatat ggaaaagagt cagattcagc taatataaca agtaaatcat
     3901 atggcaattt tgatatttat ttgggatatt caccaataaa tgcaaattat acattttcta
     3961 aatatgataa ttctttatta aatgaaataa aagctattga agatgtaaca gatgttgaac
     4021 ccaatattta tttaaaagga tatctaagaa atgctgactt agaagaagat tatttagatg
     4081 agctaaaaag aactgaaata aataataata atgagtctac agttttaatt cgaggttaca
     4141 ataaagagct attaaataat atagataaat atatagataa aggcgaaaat gtttatagtt
     4201 atacagacag ggattataaa aatgttttat tggtaaataa tttttattct agaattaaat
     4261 tgtcaaataa tactcagatt ataaaatcac ctaaaatagg agacttaata gatataaaaa
     4321 ttcctgtata taaagatgga gagtataaat atataaatac aaaagtaaga atcgctggaa
     4381 taatgaaaaa tagctatata tcagagcaag atggagaatc tcaatcaggt ggaattc
//
LOCUS       DAGQVA010000141         4416 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.146, whole genome shotgun sequence.
ACCESSION   DAGQVA010000141 DAGQVA010000000
VERSION     DAGQVA010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.146"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..1860
                     /locus_tag="MIV85_003678"
     CDS             <1..1860
                     /locus_tag="MIV85_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBY2962973.1"
                     /translation="STKDTEVKAKYTEIKILGTGDLHSILTDSMVSYVNEEREKNKNL
                     LMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEYDDIIKSSKDEVPIVKDMAKLKY
                     DAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSANIYEQSGENYVQPYVMKNIKTDE
                     GNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQADYKGKLYANDLVEDAKKWIKV
                     MEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTVDGIDAIVAGHTHEKIDEHKYKN
                     KSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKEKSSKLKIIDKEVSIVATADLHS
                     HFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEMTQWYKEWKSIRDNNSDKTISRC
                     PMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLDAVIEDFEQVAISVLSANIYRQS
                     GKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGLKNVNLQEQFQYKDKLYANDLVE
                     DAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNRIKELATTVDGIDAIVASHTHEK
                     IDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKEKGSWIINDKFSKTIEVE"
     gene            2261..4165
                     /locus_tag="MIV85_003679"
     CDS             2261..4165
                     /locus_tag="MIV85_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBY2962974.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKI
                     FGKEVNIITTSSLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         1868 a          448 c          831 g         1269 t
ORIGIN      
        1 agtacaaaag atacagaagt taaagcaaaa tatacagaaa ttaaaatatt aggtacaggt
       61 gatttgcatt caattttgac agactctatg gtttcatatg taaatgagga aagggaaaag
      121 aataaaaatc tgcttatggt agatgcggga gatttctatg gtacacaaag tagagaaatg
      181 tgggaatggt cttctggaaa aaagttaatt aatattaaaa gaaatggtag agcagagtat
      241 gatgacataa ttaagagtag taaagatgaa gtacctatag ttaaagatat ggcaaagttg
      301 aaatatgatg ctgtagtttt gggagataat gaatttgttt caaatgataa gcaaagtctt
      361 gataaactag tttctgattt taaaaataat aatatgccat tggtatcagc aaatatatat
      421 gaacaatctg gagaaaatta tgtacaacca tatgtaatga aaaatattaa gacagatgag
      481 ggcaatgtaa aagttggaat actaggtctt actataaaag aagtagggga aacccttggt
      541 cttgaggatt ttgaaaagga taaaaaagct agagagcttg gagaacaagc tgattacaaa
      601 ggaaaattat atgcaaatga tttagtagaa gatgcaaaga aatggataaa agttatggaa
      661 aaagaaagtc cagacataat agttgcagtt gtacactcag gggaagaacc taaaacagat
      721 agaaatccag gaaatagaat aaaagagtta gcaactacag tggatggaat agatgcaatt
      781 gtagctggtc atactcatga aaaaatagat gaacacaaat ataaaaataa atctggagat
      841 gaagtaattg ttacacaacc aggttggcat ggagatagag tatcagagat taatttcaaa
      901 ttaaataaag agaatggaaa gtgggacata aaggaaaagt ctagtaaatt aaaaataatt
      961 gataaagaag taagtatagt tgctactgca gatttacatt cacatttctc tgataaatta
     1021 acagttgacc ttgttaatga acgtagtaac ccaattgaac ctgttgtagt agatgcaggc
     1081 gacttcttag accctcaaac agatgaaatg actcaatggt ataaagagtg gaaaagtata
     1141 agagataata atagtgataa aacgattagt agatgcccaa tggtcatgga tatgaatcag
     1201 ggaatgtatg atgcagtagt acttggaaat catgaatttg tatccgaaaa agatgaattt
     1261 tggtcagatg aacgcctttt agatgctgtt atagaggatt ttgaacaggt ggcaatttct
     1321 gtgttatcgg caaatatata taggcaatct ggtaaaaatt atgttaaacc atatattata
     1381 aaagatgtgg agacgagtga aggtaatgta aaagtaggaa tattgggact tactataaaa
     1441 gaagtaggta aaggtcttaa aaatgtaaac ttacaagagc aatttcaata taaggataaa
     1501 ttgtatgcaa atgatttagt ggaagatgca aagaaatggg taaaagttat gaaaaagaaa
     1561 aaaccagata taatagttgc agttgtacat tcaggagaag aaccaaaaaa tccaaaacat
     1621 ccaggaaata gaataaaaga actagcaact acagtagatg gaatagatgc aattgttgct
     1681 agtcatactc atgaaaaaat agatgagcat gaatataaaa ataagtctgg agaaaaagtt
     1741 atagtgacac aaccaggtga gcatggtaaa tattattcta aaattacctt taaagtaaat
     1801 aaagaaaagg gttcgtggat tattaatgat aaattcagta aaacaattga ggttgaataa
     1861 ctttataaaa tttatagata aagtaaatta tctgatattg acatgatata taagataaag
     1921 tttctaatat tagtataatg cataatgtga aatattttaa taataagaga ataaacaaga
     1981 caaataaaaa tattttaaca tgtaagatat agtatgaact attatactaa tgcttacttt
     2041 ataatttgaa catgttagaa taagtcttat ttgaaaattt tagtgtatta gagtaagtat
     2101 tattttacca gtaaaaaata ttgagaacta tatgtagatt tgcttaaaaa ggaatttaca
     2161 tatagttctt ttcgtataat aaatagtaca atcttatatg gtaaagataa agtgtgatat
     2221 taaattttat tatcatccaa aatctaagga ggagtctctt atgaaaataa aatttattat
     2281 agtagcatca ataatatttt taatagtatt acttgtgggg tgtcaaagta ctaaagacac
     2341 agaaatcaat gtactcgcca caagtgattt acattcaatt attccagata atttaatttc
     2401 ctatgtagaa gaggagagaa aatatgatga gaatctactt atggtagatg caggagattt
     2461 ttttgacatg caaagtggtg agatgaataa gtggtttact ggtcaaaaat tagtaagatt
     2521 taaagatggg ataccagagt acaaaaaaat agctgaacca cgtgaaggag aagttccatt
     2581 ggctaaaaaa atggcaaagc tgaagtatga tgcagttaca tttgggaatc atgaatttgt
     2641 atctaatgac aagcagagcc ttgataaatt ggtttctgat tttaaaaata acaatatacc
     2701 attagtatca gcaaacgtat atgaacaatc tggagaaaac tacgtaaagc catatgtaat
     2761 gaaaaatata aatactgaca agggaactgt aaaggttggt atacttggtc tgactataaa
     2821 agaagtaggg gaacgttcaa ggtttaaaag ttttgaacaa gataaaaagg ctagagaact
     2881 tggggaacaa cctcaataca aagggaaatt atatgcaaat gatttagtag aagatgcaaa
     2941 taagtgggta aaggttatgg aaaaaaaaga aaagccagat ataatagttg ccattgtaca
     3001 ctcaggtgaa gagccaaaaa atcctaaaaa tccaggaaat agaataaaag aactagcaac
     3061 aactgtagag ggaatagatg ctattgtagc aggtcataca catgaaaaaa tagaacagca
     3121 tacatataaa aataattctg gtgaagaagt aatagtaaca cagcctggag ctcatggtaa
     3181 tagtatatca aagattaatt ttaagttgga taagaagaat gataagtggt ttataaaaga
     3241 caaatatagt gaattaaaga tttttggaaa ggaagtaaat ataattacaa cttctagtct
     3301 gaatccaaaa ttttcagatg aaatggcagt taatttgttt aatgaaagag atagagatgt
     3361 tcaacctata tttatagata ctggagattt tttaaatact aatacaaaag aaatgactaa
     3421 gtgggctaaa gagtggcaat acaatgaaaa taaaggcatc tataaaaaaa taaatgaatg
     3481 gccaattgta tatcttggtt atgatgctgt agtacttggt agccatgaat ttacagagga
     3541 taaagagact tttgaggaaa aaaaatctac attggattat attatagaaa actttgaaga
     3601 aatgaagata ccagtattat cagctaatat atatgatgaa tctggagaaa attatgtaaa
     3661 accttatata attcataatg tagaaactag ggaaggaaat ataaaggttg gagtattagg
     3721 tcttactact actgataagg atgaagaaga cttaagtagc tcaagcttaa gcaaagactc
     3781 aaagacttcg aaaattcctg aagaaacagg aaagttatat actaataatc tagtaaaaga
     3841 tgcaagcgaa tgggtaaaag ttatgcaaaa ggaaagtcct gatgtgattg ttgcagttgt
     3901 acattcagat aataatagta ctctaaaaaa tccaagtagt gaagtcaaaa aacttgcaat
     3961 gtcagtagat ggaatagatg ctattgttgt aggtcatacg aaaaataagg tagaagaaca
     4021 tatttacaaa aataagtctg gggatgaggt tatagtaaca caatctggag aagattgtta
     4081 ttcaaaaata agtcttgaac taagaaaaga aaatggcaag tggaatatca taaacaaata
     4141 tagtaaagca ataaaaatga agtgaattta ttgatatata aaccattatt aacactgatt
     4201 tttataatat aataaatact gattctataa tataattaac actacttttt ataatgtcat
     4261 caacactgat tctataatat aattaatact acttttttaa atataatcaa tactgattcc
     4321 ataatataat taacactact tttttaaata taatcaatac tgattctaca atattattaa
     4381 tactactttt tataatataa tcaacactac ttttta
//
LOCUS       DAGQVA010000142         4413 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.147, whole genome shotgun sequence.
ACCESSION   DAGQVA010000142 DAGQVA010000000
VERSION     DAGQVA010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4413
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.147"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            159..605
                     /gene="rpiB"
                     /locus_tag="MIV85_003680"
     CDS             159..605
                     /gene="rpiB"
                     /locus_tag="MIV85_003680"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBY2962975.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            635..1300
                     /locus_tag="MIV85_003681"
     CDS             635..1300
                     /locus_tag="MIV85_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBY2962976.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            1410..2912
                     /locus_tag="MIV85_003682"
     CDS             1410..2912
                     /locus_tag="MIV85_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBY2962977.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(3224..>4413)
                     /locus_tag="MIV85_003683"
     CDS             complement(3224..>4413)
                     /locus_tag="MIV85_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2962978.1"
                     /translation="SNKMFYNTNLIIYNFIIISIVYIIYENIKYNNYNLKDMSITYVF
                     FSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFMYIYYAEAIAIVILFTLVN
                     TVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVIGDDEISTLAKSINNITGG
                     LETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDMLKNNDFDRETINDYINILD
                     KKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQSIVEFEDKIQNSSLDFIIE
                     TPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDMFIKEENIILTFKNISNDK
                     LNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENAHMEIIIDADLFKVMLTFR
                     KVN"
BASE COUNT         1737 a          466 c          717 g         1493 t
ORIGIN      
        1 ataacaaatt gatttgacat aagtcaatta aagctgtctt aaaaatagaa agaaatttct
       61 acaatgggac agctttattt ttacaatact ttatttttat gataattata aaatagtctg
      121 aaagtaatca aaaaaattat aaaaagaggt gctatttaat gaaaatatct attggatgtg
      181 accatggtgg ttatgaatta aaggaatata taaaggaaaa tttaataaat aaaggtatag
      241 aagttgaaga tgtgggtaca aattcaaaag aaagtgtaga ttttccaata tatgcaaaaa
      301 aggtaagtca aaatgttcaa agtaaaaaat ctgatttagg catactttgt tgtggaacag
      361 gaataggtat gtctattgca gcaaataagt ttaaaggaat cagagcagct gttgtttctg
      421 actgtttttc agctaaggca actagagaac acaataatac aaatgtactt tgtttaggag
      481 aaagagttat tgggaaagga ttagcaatga gaattgttga agaatggtta aattcaagtt
      541 ataatggaga aagacatgca agaagattac aaatgattga tgatatagaa aaagaaaatt
      601 tataaatata taatttacaa caagggggag cgttatgtct attatttgtg cttcaataat
      661 gtgtgcagac caaatgaagt taaaagagga attagaagct cttgaagaag caggtgtaaa
      721 attacttcat tgtgatgtta tggatggaat atttgttaaa aacttggcta tgggaccaga
      781 gttattaaaa tcaataagtg aaaatacaac aataccttta gacatacact tagccacaga
      841 aactccagat aaatatattg atatgatgtc ttatataaag ccaaaatata tttcttttca
      901 tgtagaatca agtacaaatg taaaagctga tatacaaaag ttaagaaatt atggtatagg
      961 gccagtgtta gcaataagcc ctcaaacaag tgtggataaa atagaagaat atataagttt
     1021 agttgagggt atcttagtaa tgacagtaaa tccagggttt gcaggtcaaa agtttaatct
     1081 ttctgtattg gataagttgg ataaacttac agagatacta aaagattatg ataatcctcc
     1141 atttatagag gttgatggaa atataaataa ggatactatt aaacttatga atggtaaaaa
     1201 agtagatata tatgttgttg gtacttcagc tttatttaat gataagcctc caatttcata
     1261 taaagataaa atagaagaac taaaagaaag tataaagtaa ccatgtaata aaattataat
     1321 atgtttctgt ttaatagtaa aaatttaggt ggaaacaaga aattttataa tatttaataa
     1381 aaattttggt tgagtaagga gaatttttta tgggagacct atataaacta caaaatggta
     1441 ctgatattag aggaatagcg tatgaaaatg attctaaaga agttaaccta actgtagaag
     1501 aagtaaaaaa aatagctaaa gcgtttcata tttggttaaa agaaaagact aagaaagata
     1561 aagtaactgt tgccatagga actgattcta ggataacagg aagccaattt agaagtactg
     1621 ttattgaaac tttaactaat gatgattgta atgtaattga ttgtgagatt gccacaactc
     1681 cagctatgtt tatgacaact attatggatg gatacaattc tgatggggcg attatgatta
     1741 cagcaagtca cttaccttat tactataatg gtttaaagtt tttcacagaa agtggaggtt
     1801 tagaaaaaac tgatataaaa gagatgttgg atatagctgt taaaaatgat agtgtagact
     1861 atgaggaagt aaataaaaaa ggtgaagtta tagtaaaaaa tttaatagaa gattattcta
     1921 atttattgat agataaaatt agaaaaggtg taaattcaag taaaaattat gaaaagcctt
     1981 tttctgggct taagatattg gttgatgcag gaaatggggc tggtggattc tttgctgaaa
     2041 aagttttaca catactggga gcagatacga caggtagtca gtttttgaac ccagatggta
     2101 tgttcccaaa tcatatacct aatcccgaaa acaaagaagc aatggaaagc atatgtaaag
     2161 ctgtgttgga taataagagc gacctaggaa taatctttga tacagatgta gacagagctg
     2221 ctattgtagg taaaaatggc aaaccaataa ataaaaatgc tcttatagct gttatatcat
     2281 caatagtatt agaagaacat ccaaaaacag ctatagtaac agattcgatt acttctgaag
     2341 gacttgctaa atttataaat gaattacaag gaagacatca tagatttaaa agaggatata
     2401 aaaatgtaat aaatgaagct ataagattaa atagtgaagg tgaagagtgc catttagcta
     2461 tagaaacgtc tggacatgct gctttaaaag aaaattattt cttagatgat ggggcatatt
     2521 taatagctaa aattttaata aaagtagcaa agctatcctt ggaaggaaag actatagaag
     2581 aattgataga aaaccttgaa gaagctcaag aagagaaaga agttagaata ggcattaata
     2641 aagaagattt tagaacatat gcagaggata tattaaaaga tttagattct catgttaaga
     2701 gtattgatgg atggtctgta gcaccaaata attttgaagg cataagagtt aattgtgatg
     2761 aatcaaatgg agatggatgg tttttactta gaatatcact acatgaacca ttattagctt
     2821 taaatattga atcaaataaa attggcggag cagaacaaat ttattctaag ttaaaacttt
     2881 tcttagaaaa atatgattta aaaggtcttt agggtaaata gaaagaatat atttatattg
     2941 aagaataaat gtaaatttgt acctaagatt acaaatatta caaaattgta atcttaggta
     3001 acagagatgt aactgattat ggaaacacta tgtgatatta tagatacaga gagatgaaat
     3061 atgtgatgaa ttatagagaa atataattta aaatgtatta atatcacacc aaaaaggtat
     3121 aatcaaaaaa tatgtaaata taaaccccaa catttagaaa aagacctcta aggaggtttt
     3181 tttcttgttt aaataactta aaatatattt ttatattaat atatcaatta acttttctaa
     3241 aagtaagcat taccttaaat aaatcagcat ctataattat ttccatgtgt gcattttcta
     3301 attcaattat attttgagca attgataaac caagaccaga gccatctgtt tttctagata
     3361 tatcacccct tctaaatctt tctattaact cttctggttt tagatttagt ttatcatttg
     3421 aaatattttt aaacgttaat attatatttt cttcctttat aaacatatct atatagaccc
     3481 tagtgttagg catagagtat tttagtatat tgcaaattag attctcaaaa actctccaag
     3541 tttttttacc atctatcatg gtaaaaacag catattcagg tgtttctatt ataaaatcta
     3601 aactgctatt ttgaattttg tcttcaaatt ctacaatact ttgaattaaa agttctctta
     3661 tatcggtttt tgttatatta aattctacat ctccactact tagcttagat gcttcaaata
     3721 tgtcatctat taataatttt aatctttgtg attttttatc taaaatattt atatagtcat
     3781 ttatagtctc tctgtcaaag tcattatttt ttaacatatc aacatagctt aatatagatg
     3841 taagtggagt ttttaagtca tgagatacgt ttgtgataag ctctgccttc atcctttcat
     3901 tttttatatt agcatctaca gcagtttcaa gaccgcctgt tatattattt atacttttgg
     3961 ctaaagtaga tatttcatca tctcctataa cttctaattt atactttaaa ttgccatttt
     4021 ctatattttt tatatttttt gatatgttat ttatgtaatt aaacttaaca gataaaaagt
     4081 tgtatatata aaaatgaaaa actgtgttta caagtgtaaa taaaattact atagctattg
     4141 cctcagcata atatatatac ataaagaata tcaaaacaag atattggata atagcttgta
     4201 caactataga tattaaaaat actatagcta attttttatt tatagttttt ttattataca
     4261 tactaagtaa gtttgaaaag aatacatatg ttatagacat atcttttaga ttatagttat
     4321 tatatttaat attttcatat attatataga ctatagatat aattataaaa ttgtagatta
     4381 ttaaattagt gttgtaaaac attttattac ttg
//
LOCUS       DAGQVA010000143         4289 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.148, whole genome shotgun sequence.
ACCESSION   DAGQVA010000143 DAGQVA010000000
VERSION     DAGQVA010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.148"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            231..1310
                     /locus_tag="MIV85_003684"
     CDS             231..1310
                     /locus_tag="MIV85_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBY2962979.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="MIV85_003685"
     CDS             1634..2002
                     /locus_tag="MIV85_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBY2962980.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHENAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDNDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="MIV85_003686"
     CDS             2119..2922
                     /locus_tag="MIV85_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBY2962981.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3307..4197
                     /locus_tag="MIV85_003687"
     CDS             3307..4197
                     /locus_tag="MIV85_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBY2962982.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVFKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
BASE COUNT         1642 a          470 c          803 g         1374 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 tcatcaagga tgaagaacgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tgctacctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtacgg taaaaataaa tctactaact
      901 ggattgtaaa gcatggttgt agaactctac taaaaaaagg aaatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagct atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttagcac aagatgctgt
     1681 taagataaga aaatattttc atgaaaatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaaag gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggataa tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtttttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccaa atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgatgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaacaa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaattaca tactcattag
     2941 gtaaattatg tagtatatgt gtttatagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat ataaattttt
     3061 aagcgaaata catcaaaaga agtattagaa ttagtggaga taaaacagct attagagatt
     3121 ataaataaat agttttaaag gtactacgaa tatagaggaa ggtaaatcat acgttattca
     3181 aggattataa atgattagtt taaaagtact atcggacagg tctctgcata tttaaacctt
     3241 agtaaaggta gttaaagtag tagtttaaaa actaaaaaat tatataaagg aattaggtat
     3301 aagaaaatga ttgagagtat accagcaaaa caaattttac aaaaagtgaa atttgacaat
     3361 acaagatggt ttggaattga ctataatatg aatctctatc gtggttgttc tcatggatgt
     3421 atatattgtg atagccgtag cacaatatac aacatagaga attttgacaa agttagatat
     3481 aaagaaaatg tgatagagat tttaagtaaa gaattgcgtt caaaaagaaa aaaaggggta
     3541 gtaggcattg gagctatgtc tgacacatat aatccttttg aaaagcaact ttgtattaca
     3601 aagcaggcac tagatttgat ttcggaaaat cattttggag tgtctattga tactaaaagt
     3661 agtttggtgg ttagagatat accgattttg cagaaaatta aaaaaaataa ttctgctatt
     3721 gtaaagttga ctataaccac tgcaaatgat gaattatcaa agaaaataga accttatgta
     3781 aatccaagtt ctgtacgatt tgaggcagtg aaagaactta atgattctgg aattttttgt
     3841 ggtatattat tgactcctat gcttccattt ttgactgata ctaaagatga aatacgagca
     3901 attgtagaaa aagcacacaa ggctaatgca aaatttattt attgtatgta tggtgtaaca
     3961 atgcgtagtg gtcagcgaga gtttttttat gagcatttaa gagatatatc accaaaattg
     4021 gtatttaaat atcagaaaac atatggttta aactatgtat gtactgtaca aaataaagat
     4081 tgttgtgaga agttgttaag agaagaatgt gcacgttatg gtattttgac ggatatgaaa
     4141 gatattataa aagcgtacaa gaggtcggag tcatatactc aaataaaatt tttttaagat
     4201 aggctttgga tgagatataa tagtggtgat tgatgtgttg atattatagt tgattgttag
     4261 agaggatatt atagatgaat attagtatt
//
LOCUS       DAGQVA010000144         4245 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.149, whole genome shotgun sequence.
ACCESSION   DAGQVA010000144 DAGQVA010000000
VERSION     DAGQVA010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.149"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(364..582)
                     /locus_tag="MIV85_003688"
     CDS             complement(364..582)
                     /locus_tag="MIV85_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2962983.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            complement(583..990)
                     /locus_tag="MIV85_003689"
     CDS             complement(583..990)
                     /locus_tag="MIV85_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962984.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(1076..1564)
                     /locus_tag="MIV85_003690"
     CDS             complement(1076..1564)
                     /locus_tag="MIV85_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBY2962985.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            complement(1769..2890)
                     /locus_tag="MIV85_003691"
     CDS             complement(1769..2890)
                     /locus_tag="MIV85_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBY2962986.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTQKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            complement(3263..3433)
                     /locus_tag="MIV85_003692"
     CDS             complement(3263..3433)
                     /locus_tag="MIV85_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962987.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            complement(3605..4048)
                     /locus_tag="MIV85_003693"
     CDS             complement(3605..4048)
                     /locus_tag="MIV85_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962988.1"
                     /translation="MIEIKTIEINKKSQIDLLILADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
BASE COUNT         1437 a          701 c          371 g         1736 t
ORIGIN      
        1 ctattagctt gttttttacc tataattaat tcattctcta atctataagc tttctttttc
       61 atctataaat cattcattct ttaatctatg agcttggttt ttcatctata agtcatttat
      121 tctctaatct ataagctttc tttttcatct ataaatcatt cattctttaa tccattagct
      181 tggtttttca tctataagtc atttattctc taatctataa gcttacttct taatctataa
      241 atcattcact ctttaatcca ttagcttggt ttttcatcta taagtcattt attctctaat
      301 ctataagctt ggttttttac ctataattaa ttcattctct aatgcataag taatacatga
      361 aatttaaata ttattttctt caataaattc aaacaactct tctacagttg tatcaaatac
      421 cttagcaata tccattgcca gttttaaaga aggattgtag cgaccatttt ctaaatgtac
      481 aatagtttca cgtcttactc ctactgactt tgcaagttca ccttgtgtca taaggttctt
      541 ttctctatag gatttaattt ttgtctttag taatactgac acctaattgt atatcccctt
      601 tctgtcaaaa tatataaata gaattaactt caacaaggat tgaataaaca aaatgactaa
      661 taaagacatt cctatattta aatttgacac atttatgtcc aaagttacaa gaaatataga
      721 tactatagct acagaaaaaa acaatacttt tattgcaata tcattaactc ttgatagtat
      781 acattttgat gcctcatcaa ttaaatcatc atacttttta ttatagaccc actgagctcc
      841 catagctaat acccaaataa ttataggaag atattcaata ctacttcctt taaaaaaata
      901 cttatttact aatgtagctc caatacaata agaaattccc aatatttctg aaataagtgt
      961 tgatttaata ccagtttgtt gtttagacat ataaaatccc ccttaaaaag ttatgtattt
     1021 ataacacctc ttgttataaa tatataactt ttttgaataa atttcaataa aaatattatt
     1081 ttgcaacaaa ttcttttatt aattttacat tagatagagg cactttagat gtcactcctt
     1141 gcaatgtcaa atcttctata ttaacttcat ttaattttga acacagttct aagtcaaata
     1201 ttctttccca acttaccttc ttttcaattt gttcatcttc ataaagctct acagtaatat
     1261 ccattaaagg taaatgccat aaatcaaatt ctgataataa cacattgtct tcacttattt
     1321 ctatttcaag taaaacacct ttttttcctt tttctaaata accactacat cttaaatcag
     1381 gtctcttcgt ccaaacccat atcatactat catcaaattc atatattcta tttgtcattt
     1441 gactatacat ccatttgtat ggaatatcaa agtcttctaa tataaaagaa taatcatttg
     1501 atagatattt attgttttta ttgttattcc aaaattctaa agtctgtata gtataaaatt
     1561 tcatatataa atcaacccct ttgtttttct ataagaagga gatggttcaa acttttattt
     1621 tgaattatct cctttattta tacacctctt tgtacctatt atttatatat ctctttatat
     1681 ctaccatatt taaataacaa agttttatat taatttaaat ttaaaagagg aagctttgta
     1741 tttatctagt gccatctcaa tcatagtatt agttttgatt atagactttt tcaacctctg
     1801 atttattcaa atcatctata atatcgcata tttcactcaa attgtatcct ttatttttta
     1861 attttatgat gatattaaat ttctcttctc ttttcccttt tgcaatacct ttttcgatac
     1921 ctttttcgat acctttttca ataccttctt gaaaaatttc ttctttaaaa tttctacttt
     1981 tattcataat atacgcacct ctctttaaat ttaataaata gtcctcatta ctacctaatt
     2041 cttttaatct atcaagtgct cttttaataa cataatccgt tttagatagt attctaatat
     2101 ctatatgaga aggattatca ataagtttac cccatattag aactctgttt gctatacaac
     2161 tggatttacg aatttttgga agttctataa aatataatgc agttttacta gaaaaaatat
     2221 ctggatgccc gtccattgtt aatctcaggc aatttacata atcttctatg tgattatatt
     2281 ttacatgatt tagtatatgt attccaacag tttttccaat ttctttatat tctttacctt
     2341 cttctaactt tctaccatgt acacgactaa gataatattc agctctttcc aaataatcct
     2401 cttcaagagc tctttgcatc tcaatattta tatggttacg ttcttcatct tcagccaaaa
     2461 tatcaagtct aggtcttttc tcaccaatgt aattaattgt tgggtcggtt tcaaccttaa
     2521 ttattctttt tatttgagtg aactgtttga tattcctatt agcatatgga gcatctttga
     2581 ggatatcatt tataaaattt gcaagtaaat cgtaatcatt atttaaagta aacaatgatt
     2641 taaatacctc atcatactca ggcttagcat acccatcttc agttacaact tctccaacat
     2701 tttcactagt caatatttct tttggaatta aatccttgat tttatctaat ttttcattag
     2761 aaaaatcacc tctactaagt atgtcattta atttttgggt ccattctctg tccttttctt
     2821 caattatagt tcgtttatac tcttttgatg ttttaataat cttagatttt tcttctaatt
     2881 tttctttcat atcaacacct cttttttatt attacccatt tcttcatacc aaagtctgaa
     2941 cttctaagta aaatttgcat tattgaaata agaaccttat aaacttatat atcattacta
     3001 aagttaagac tttaaagaga agcacttaga ttacaataga ttttagatag ctttcttttt
     3061 aaaactattg ttgataaatg aatgaatata agggtatgta ttaaaataga gatactcatc
     3121 tttttcattg tttaagtaat gaaaatatat tttatttaat acaaaaaaga gtgccttata
     3181 aactaaaagt tcacttcgag acactccctt acattttgtt tcttaaactt tacaatatta
     3241 catacttatt tattaattta atctatgcat acttaaccca ataataaagt acatatatcc
     3301 aactcattaa gccatgaaaa atagcccatg gaatagattt ccatgcagta taagaaataa
     3361 tcattgctaa acaagaacca aaagaaatac cctttttaac agttgatttt atagtattat
     3421 tatttgaatc cataattaat cctccaaaat tcaaaataaa caagttatta tatatcttat
     3481 ttgaatctaa tacaatataa cagcttctaa ataaattata ctcttattat acataattta
     3541 taaattataa ttccgataat tatatgaatt aattaattat attaacctaa aaatattatc
     3601 ctatctaaaa gttatatgat agatacaaca tgtcaacaca ttgtaattct ccttcaaaga
     3661 ttggttctgg ataattatct acaaaaaagt ttttaatttt atgtgaataa acaaatccaa
     3721 acttctcata aaaaggaact ccactttcag atgtaccaac aaccattgat gaatattttt
     3781 tactataaac atctaaaaga tgataaatca tctttgaggc ataacccata ttttgaaaat
     3841 gctcatatgt agcaatgttt tttaattcac atatttcttt ggaaatttca tttacaactg
     3901 ctatacaagt aagttcttta ttatcataca atgcgtacat agttccttta ttgagatatt
     3961 tatcaatcat ttcttcacat gggtcagcta atattaaaag gtcaatttga ctttttttat
     4021 ttatttctat agtttttatt tctatcataa gttctccacc ctcactttat tcaaacctta
     4081 atttaacaaa cttcttacag tacttattta gttcattttg atatatattt ttacttttta
     4141 aaatatagtg ataattccct agaatattaa tattaataat aaattataat atcagctcta
     4201 gcaattacct agaatatcaa tactaatatt catctataat attag
//
LOCUS       DAGQVA010000145         4172 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.150, whole genome shotgun sequence.
ACCESSION   DAGQVA010000145 DAGQVA010000000
VERSION     DAGQVA010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4172
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.150"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            111..1310
                     /locus_tag="MIV85_003694"
     CDS             111..1310
                     /locus_tag="MIV85_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBY2962989.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            1362..1865
                     /locus_tag="MIV85_003695"
     CDS             1362..1865
                     /locus_tag="MIV85_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2962990.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            1972..2289
                     /locus_tag="MIV85_003696"
     CDS             1972..2289
                     /locus_tag="MIV85_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2962991.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            2447..3406
                     /locus_tag="MIV85_003697"
     CDS             2447..3406
                     /locus_tag="MIV85_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBY2962992.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            3521..>4172
                     /locus_tag="MIV85_003698"
     CDS             3521..>4172
                     /locus_tag="MIV85_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBY2962993.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKI"
BASE COUNT         1723 a          305 c          726 g         1418 t
ORIGIN      
        1 gtaaataata ggatgagttc tattttaata caattaaatt aagcttagtt tgaaatttgt
       61 atctaaaaag taaagtaatc tagaattaag aaaatggaga tagaattata atggaaaaat
      121 tatattatac aaatcagtat ataagagatt ttacagcaga aataattgaa ataaaagaag
      181 tagaaaataa gtatcatgtt ttattagata agacagcttt ttttcctggt ggaggaggtc
      241 agtttggaga cctgggaaaa atagagaatg atgatgtaat aaatgtgtat gaagatggaa
      301 aaaaaatata ccatgtatta gataaaaaac ctataaagat acataaggta aagtgtagta
      361 ttgattggga tagaagagaa gatggaatgc atcaacattt tggacaacat gtattgtctg
      421 gatgtttttt taaaactttt aatgcaaata cgacaggttt tcatttggga aatgagtata
      481 gtacagtaga tatagaaggt aatttagaag aggataaaat tagagagata gagttgtttg
      541 ccaatgaaat tattcgtcaa aatatacaag tagagacatt acttccaacg aaaaaagaac
      601 taaaaaagat ttggttaaga cgtgatttgc caaatactga tgaagagata agagtaataa
      661 aaataggtga tttagatacg aatgcatgtt gtggagtgca tccaaaatca actggtgaat
      721 tgagaatgat aaaaataaag aaatgggaaa aacataagtc aagtacaaga atagagtttc
      781 tagcaggtaa aagggcagtg gatgaagtat tgaagaggga tatatatttg actaaaatat
      841 gtagatattt aagctgtagt gaggaagatg ctataaatgg tattgtaaat ctaaatagta
      901 aagtggaaga ggctttaatt aaaaaaagaa ggcttgaaga agtagtatct acatatcagg
      961 tcaaagaaat gattgaaaaa gcaaataagg ttggcaatat ttcggtcatt aaaaaaattt
     1021 atgatgatga agatttgaaa tatgtaaata agatagcaaa taaaattgca gaatatgaaa
     1081 atagtattgc attattagct gttaaattta atgataaaat aaatttagtt tttgcatgtt
     1141 ctaaaaattt aaaagatatt aatatgggag ttttattaaa ggatgcaata aatcttatag
     1201 atggcaaggg tggtggaagt aaagtattag ctcaaggagg aggtaagaat aatggaaatt
     1261 tagaggctac acttgattat gcatttatga agatagaaaa aactctataa atatattata
     1321 taaaaaacct tagtagataa aatagatatg gaggaataag tatggagcaa caaaaggact
     1381 acatagagtt atatgaaaat gaagaactaa tagagataag agaagcacgt atggatgatt
     1441 tggatacaat agcaaaattt aattataatt tggctaaaga aactgaagga aaagaacttg
     1501 atatggatgt tttaactaaa ggtgtaaaag cattgttatt agatgagaga aaaggaaaat
     1561 atcatgtata tacagtattt gataaagttg ttgcacagat tatgtataca tatgagtgga
     1621 gtgattggag aaatggaaat ttcctttgga ttcagagtgt atatgtagat aaggaatata
     1681 gaagaaaagg tatctttaat tatttattta attatataaa aaatatatgt gataaagatg
     1741 aaaatatagt tggaatgaga ttatatgtag aaaaagaaaa cataaatgca aaagcaacat
     1801 atgagtcttt aaatatgtat gagtgtgatt ataatatgta tgaatacgaa gtagtacatt
     1861 cgtaatataa atttgtaata ctgttatact gatgttataa agtattgatt atattgacga
     1921 ttatatgaaa taaactggat attataatta gaatttttag ggggtataaa aatgggcgtt
     1981 ttaaaaggaa tgttttatgt atttttattt ttagatttag tgtcaatatt ctgtttcttt
     2041 ttcaataaag gaaaaatagc atctaataaa attgtgttta atgcaatagg agtacttaca
     2101 tttgtacttt gttttatgct ttttagttat tatcccaata ataatcttat tggaaaattt
     2161 attgcttctc tattttttat atttggagtt gcaggagtta tgttgaaaga aaaaaatttt
     2221 ttatatgcta gacttctttt aactgtagtt atagtttttt ctacattaag attgttcgtt
     2281 attcaataaa atgtatttgt atgaaaattt attaaagtct acacatttaa gtgtaggctt
     2341 ttttgatttt ttgtttgaaa attaaggaaa ttttaaggaa attttaaaat cgtcttaaat
     2401 atttattgat atacttaaaa tattaatagc gaaaggagac ttatcagtga tagaaagtaa
     2461 aaagtcagaa aaattgttac tgtcaattat atacataata tttttggtat atattttaat
     2521 gattataaga ataattttat ttagagatgt accaatttac gctattttca agggaacgtt
     2581 taggaatgta aatttaattc cattttatac aatatatcaa tttatagtag atagtaatct
     2641 tgactttatg aaagctactg taaatattat agaaaatata ggtatattta ttcctatggg
     2701 aattttttta cctatagtat gtaaaaatct aaataaaaaa actataatta tagtaattat
     2761 acttgttagc ctagcatttg aattaacaca atatattttt gctcttggaa gtagtgatat
     2821 agatgatgtt attttaaatt cattaggtgg cataattgga attaatattt acataaacat
     2881 gaataaatta tttcccaatg atattaacag atttaaggct ataataggta ctagtttagt
     2941 tttaggagtt ataggattag gagttatttc taaaaattat cataacttac taacttttaa
     3001 atttagacct gatagaaaaa tatcaaaaat attaattgaa gaaaataggg aaataattaa
     3061 agatataaat aaagatacag tagatatagt tgggacattt gagagcttta aaaaaggaat
     3121 aataactatt aaagcaggtt ctaataacaa agtaaagaga ccagagaatt taattgattc
     3181 tgatggaaat ataagaattt atttaaatga aaatacaaaa ttagtatctt atataattac
     3241 caaagaatca aaaatggata tagttaaata tgaggaattt gatgtgaaga atttagattt
     3301 attaaggaga tatgatacta ttaatgtttg gattgataaa gaaaatcagc caaaggataa
     3361 acatggtatt atggctagta aattattaat tggattgtat gaataaaata ttaaacaaga
     3421 ataaaagaat aacaaatata aaaaacgaaa aaactatttc tataattatt tttacgttgt
     3481 gcataaaata agaacattag tgaaggagta gagataaatt atggagataa taaaatatat
     3541 cttgtacttt tttatatatt catttttagg atggacagta gaaagtatag gatgttctat
     3601 agcaagcaaa agaataatca acagaggttt tttaaatggt ccaatatgcc ctgtttatgg
     3661 ttttggagcg gtaattgtga tatcactatt gggaagattt aataatgtag taatagtatt
     3721 tctattagga atgattttaa ctacgatact agaatatttt acaggattta ttttagaaac
     3781 cttatttcat gctaaatggt gggattattc tgacagaaaa ttcaatataa agggtagagt
     3841 atgtttaaaa aatgcaatat actttggtgt aatgtctgtt ttaataataa gatttataca
     3901 tccatttata aaatattttg taagtataat tccatataga atattaattt caatggctat
     3961 aattacaaca ctttggacta tacttgattt gattgttact attataacac ttaaaaaatt
     4021 agatataaag ttaaacttat tagacgatat aattacagac cttaatgata taaatgtgaa
     4081 attggataaa tttgatagag gagaaataca agctttattt aaaacaataa ataacgacga
     4141 attagaagtt agagaaaaaa taaacaaaat aa
//
LOCUS       DAGQVA010000146         4003 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.151, whole genome shotgun sequence.
ACCESSION   DAGQVA010000146 DAGQVA010000000
VERSION     DAGQVA010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4003
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.151"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            74..703
                     /locus_tag="MIV85_003699"
     CDS             74..703
                     /locus_tag="MIV85_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBY2962994.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            657..1085
                     /gene="ytfJ"
                     /locus_tag="MIV85_003700"
     CDS             657..1085
                     /gene="ytfJ"
                     /locus_tag="MIV85_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBY2962995.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            1333..1773
                     /locus_tag="MIV85_003701"
     CDS             1333..1773
                     /locus_tag="MIV85_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBY2962996.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            1789..3240
                     /locus_tag="MIV85_003702"
     CDS             1789..3240
                     /locus_tag="MIV85_003702"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBY2962997.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(3331..3999)
                     /locus_tag="MIV85_003703"
     CDS             complement(3331..3999)
                     /locus_tag="MIV85_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBY2962998.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFILSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
BASE COUNT         1677 a          356 c          681 g         1289 t
ORIGIN      
        1 taaaattata attctcttaa aataaatatg gataattaag tataaatagt aattttttga
       61 tgataatata aacatggagc ttaatgaatt atttaatttt aagtatttaa taatagctgt
      121 aatttttatt ataagtgtaa ctatgttgat tttaatatct catataaaca tcttaataat
      181 agctgatata aaaaacaaag atatttgttt aaagcttaat ataaaataca tgtttaattt
      241 aataaatata aatagacaac tttatccagc tgaaaatagt aaaaataatg ataaaaaaga
      301 ggggatgaag aataatatag attcaagtat attattagct gatgaccttt tgagcattta
      361 tagattatta aaaaagataa aaatacatga actttattca aatattaatt ttggaactgg
      421 aaatattggc ttaacatctt ctgtatatgt attgataaat actttgtatg gaaatttatt
      481 taatatgatt gatgcagaaa aaatgtattt aaatgtaaat ccagatttta caaaagatta
      541 tgttttagga aatataagga tacatataag gccaagaata aaagctttat ttaatattat
      601 aataatgatt aataaaatta tgaataaaaa taaaggaaat aaggaaggtg atagtaatga
      661 gagcaacagg ttcgatacag agtcttatgg aaacaactct tgaaacaatt aaaggttcta
      721 tagatgcaaa tactattata ggagacccta taaaaacaga tactacagtg gttgtaccta
      781 tatcaaaggt tacaattggc tttggtatag gaggaggaga atactcaaaa ggatatgatg
      841 ataaagatag ggaaattgaa ttaaaaaatg aaaaatcaga tacgaatttt gctggaggta
      901 gcgcaggggc tatatctgta caaccagtag catttgtagt agttgaaagt ggagagacta
      961 gaataatgag tttagatagt aatatcaatc tagtggataa tatattatct ataactccta
     1021 gagtattgga gaaaattcaa aatatatcac aaagtaataa gaatcaagat aaaaacaata
     1081 tgtaagaata aaatattttt aaatatgtat atagttttaa gtaaagtagt ggggttaata
     1141 taaatcccac tattttgttg tgtactttaa acatttatat ctaataagat tttagtttaa
     1201 aacaatttaa atagataata aagttgatat atagtataat tataaaaaga aaagaagtat
     1261 tatattatag atatataaac gcatttgaga tataagaggg agttataaat cattagtttt
     1321 gaggtgaatg ttatgagcga taaagaatta tctattttgt tgttagaaag tatgaataat
     1381 tttcataatt taataaagat tattaataac gaaagatata aaaaagataa ggttcttaca
     1441 gaaagacagt tctttgcctt agtaaaaata agaaagcatg ataaaataga gcttaaaaat
     1501 ctaagtagag atttgcatgt atctacttct agtctgtgta tactacttaa taaattggtt
     1561 gagcaagagt atgtatatag ggaagaagat agtagagata gacgaaatac tttttatgga
     1621 ataactaaaa atggagaaaa gatattggat aatgaaatac taaagtttgt atctataata
     1681 agtgataaaa tggattgcct agatatagat aataaagata aattatttac ttctttggaa
     1741 gaatctaaaa atataataga acaattattt taaaaaggag aatttattat gaatataaag
     1801 tattctaaag agatattaaa aagtttagaa aatgctataa cagtagtagc tctatttgag
     1861 ggagaagatg tttctacgac atttgataaa ataaatatga taagcagaaa ttttaattct
     1921 aaagaaaata gtatagatac tgtaacatta attgaaaata acaatttggt aaatgtttgt
     1981 cttgttggtt ttggtaagag agagttattg aatagagaaa aaattagaat cataggtggg
     2041 aatttgtgta aaaaattaaa aaatatattg aaaaatgaag catataagag tagtgatgtt
     2101 aatgtactga atctcaattt aaatagtgat gaaataggtt gttttgtaga agggatatta
     2161 cttggaaatt ataagtttga taagtataag acaaaaagta aggattttga aagaaaagaa
     2221 gttgatacta taactatatt tactgaaaaa gaagttgagt gtcaaataga aaaggctaaa
     2281 atattagcta attcaactat aatagctaga aatctagtta atgaaccatc aaacgtaata
     2341 tatccaaaaa cattagcagt agaaacagtt aaacttggtg cagagtttgg gtttaatgtt
     2401 gatgtttatg aagaagaaaa aataaaggca ttgggaatgg atgctttttt cgctgtttca
     2461 agaggttcaa ttaataaacc aagattcata gtaatgagat actttggaga taaagaaagt
     2521 acagatatat taggtctagt aggtaaagga ttgacttatg atactggtgg atattcttta
     2581 aaatcaaatg cttctatgct agatatgaag acagatatgg ctggtgctgc gagtgttata
     2641 ggtgctatgt gtgctatatc tcaaagtaaa ttaaagaaaa atgttatagc agtagtggct
     2701 gcatgtgaga atgctttatc aggaggttca tacaaacctg gagatataat tagttctatg
     2761 gcaaagaaaa ctattgaagt tttaaatacg gatgcagaag gtagacttac attagctgat
     2821 gcaatatact acattataaa caatgaaaaa gtaacaaagg tggttgatgt agctacatta
     2881 actggtgctg ctttaacatt gttaggtaat gttgcaactc ctatagtaac aaataatgat
     2941 gatttttatt gtgaattaga aaaagctgcc actttatcag gggaaagggt atggaagatg
     3001 ccaatttatg atgaatttaa agatatgata aaaggagaag aagcagacct taaaaacact
     3061 ggtggtaaaa atgctggatg tataacagca ggagctttta ttggtgaatt tgttgggaat
     3121 actccttgga tacatatgga tatagcgggg acaagtacat catcaaaatc aattggatac
     3181 aaagcaaagg gggctacagg agaacctgtt agaacattgt actatttggc agaaatctaa
     3241 aaaacaatta taaaatataa tttataaagc cacgtggata tttttgtaat ttaagattat
     3301 ctatgtggct ttatttttta tttaagtaaa ttatttactc tttttctttt tttcaagtat
     3361 aaaagtatct ctattaaata aaagagcagg tatgtacata atactagtaa caaaaataaa
     3421 cgtaaaaata gcagttgtgc tatgacttaa aaaaccataa tagtacctag agttggtaaa
     3481 tgtgtttagt aaaaatatga atgaaaaata aataaaacat atagctaagt tatctctaag
     3541 tgcatatctg ttaactctaa attttctaac atcaaccata tatatatctg cataaattat
     3601 caagcactta gataagataa agataaaata tattaagcta ggaaattcat agcccaagtt
     3661 tttagaaaaa atgagttctc caactgaaca aactaaactc caagaaaaaa atatattaaa
     3721 aagatgatac tgcttaaaaa ttagtatggc tatacacaga tatatacaaa tataattgat
     3781 tccaattggt aaagagttta gagtactata attacctgaa gaaataagta ataattgctc
     3841 tagagccata attattacaa gtaatgtaca aattatcttc tcaactgtat agctataagg
     3901 taaaatattt ttggttagtt ttggacaata gtataaaaat aatccaaata taaagagact
     3961 tacaaattgt tcactagaaa aaagaaaaat tttaaacata taa
//
LOCUS       DAGQVA010000147         3966 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.152, whole genome shotgun sequence.
ACCESSION   DAGQVA010000147 DAGQVA010000000
VERSION     DAGQVA010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.152"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            417..1673
                     /locus_tag="MIV85_003704"
     CDS             417..1673
                     /locus_tag="MIV85_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBY2962999.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            1736..2929
                     /locus_tag="MIV85_003705"
     CDS             1736..2929
                     /locus_tag="MIV85_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBY2963000.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGIYLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGENK"
     gene            3130..3510
                     /locus_tag="MIV85_003706"
     CDS             3130..3510
                     /locus_tag="MIV85_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2963001.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT         1376 a          414 c          728 g         1448 t
ORIGIN      
        1 tgataggtta tattatttat aacattaaaa atacaattta cataaaatag acatatgaaa
       61 aataaaaaat tatataataa ttatgggaat gaggttctcc cttggatgat aatatcctaa
      121 actgccaatg agctgatgac ttctatgata tcatagatgc caccagcttt ttttgttgtt
      181 taaatcgata aaatggaggt gaagtactta ctaaattttt attttttaaa tttgaagaaa
      241 tatttaatta atagaaaaaa tagtagatta tatgttaatt attttattaa gaatgggtta
      301 agagtgtacc tatatcctat caatttaaaa aacaattatg atagtcatta cattgactac
      361 agttgatgta ataaaacttt caaaaaatct tatgatgcaa atagaaagga attaaaatga
      421 tagaaaaatt taaaacttta atatggatta aaatgataat aagaattaaa agcgtttata
      481 aaacatatgg tggactattt tttttaggac tcataggtat accagttggt gcaattatag
      541 gtcttataga taccatattt ggaacggttc ttctaaaagt tacagatatt cgagaaacat
      601 atccaatgta tctgatacca tttttagcag tagtaggagt tgttattgct tattgctatt
      661 ttaaatttgg aggaaaaagt agtaaaggaa tgaatctaat atttgaggta gggcatggag
      721 aagaagaaat tattccttta agattggttc catttataat atcaggtaca tggttaaccc
      781 atttatttgg tggtagtgca ggacgagaag gagttgctgt tcagattggt gcaacttttt
      841 cacattgggt aggtaaaagg ttgcctataa aaaatgcttc tagtattttt ctagtaactg
      901 gtatggcagc tggttttgca ggattatttg agacaccaat agcagcaata ctatttgcta
      961 tggaggtttt ggttgctggt tcactggagt atcaatcgct ttttcctgcg tttactgctt
     1021 cttttacagc aagtgcagta tcaaaagctt tagggttaga gaaattttct tttgcacttt
     1081 cttctaaagt tgtatttgac ttgtcaatat tttggaagct tattgtttta ggaattattt
     1141 ttggaatggt tggtggagca tttgcatggt gtctgaaatt gtcaaaaaga aaaataggga
     1201 atagattaaa aaatcctatg ataaggattg ctattattgg agtatgtctt agtgtattat
     1261 tccttttatt ttataaagga agatattcag gtttagggac aaatttaatt caaaatagtt
     1321 tctatggtgg agaaatttat tcatttgact ggctgttaaa gtttatactt acaatactga
     1381 ctttgtcagc aggttttcaa ggaggagagg ttacaccttt gttttccatt ggagctagtc
     1441 ttggtgtatt gttagcagga ttttttaatt tgccaattga attagttgca gcgcttggct
     1501 atgctagtgt ctttggtagt gctacaaata ctttttttgc acctgtattt ataggggcag
     1561 aagtttttgg gtacagctat ttaccttatt tctttgtagt atgcgctatt tcatatatat
     1621 ttaatatgga taaatctatt tattcactac aaaaaatttc aacaaaacaa taaataaaac
     1681 aacataatgt atgattagaa gagaaagaat attagagaaa ggatagggta ggaatatgtt
     1741 gacaagttta gctttgattt ttttattagg aatggcctcg ggaggtattt ttaagaggat
     1801 aaaattacct aacttattgg gaatgttact tacgggaatt atattaggtc catatgtttt
     1861 aaatttgatt gataattcaa tactagatat ttcttctgac cttagaaaga ttgcattgat
     1921 tattatatta acaagggctg gattatcttt agatataaac gatttgaaga aagtgggaag
     1981 acccgctgta cttatgtgct ttattccagc tacttttgaa attatcggaa tgatagtttt
     2041 agcaccaaag ttactaggcg tttctatatt ggaagcagca gtcatgggtg cagtagtagg
     2101 agcagtttct cccgcaatta ttgtacctaa aatgcttaaa ttaatggaag aaggttatgg
     2161 tacagaaaaa agtattccac agatgctttt agcaggaact tctatagacg atattttcgt
     2221 aattgtgatg tttacagtat tcacaggatt ggcacaagga aatagtatat cagctattag
     2281 ctttttacaa attccagtat caattatatt aggtgtaata gttggagcag tgattggaat
     2341 ctatttagca gtatttttta agaaggttca tatgagagat tctgctaaag gggtgttgct
     2401 tttaagtatc tcatttttaa tgataagttt agagactgct ttagagggta ttgtgccatt
     2461 ttctggatta ttagcagtta tgagtattgg gattttcctt cagataaaat atcgtgtagt
     2521 tgcaagaaga ttgtctataa agtattcgaa actatgggtt ggtgctgaaa ttctcttgtt
     2581 tgttttggta ggggcaacag tagatataag ttatgcattt aaagcaggaa ttggagctgt
     2641 aattttaata tttggagttc ttttattccg tatggtagga gtattcttct gccttattaa
     2701 gacaaatttg acaataaagg aaagattgtt ctgtatgatt ggctatattc caaaggctac
     2761 agtacaggcg gcaataggag gtgtaccact tgcaatgggg atggcatctg gacaacttat
     2821 tttgacgtta gcagttctag ctatacttat aactgcacct cttggagctt ttggaattga
     2881 tgtaacttat aaaaaattat taacttctgt aaaaggcgag aataagtaaa aataaagatt
     2941 attttaactg gtaagttata ttttggaaaa ggattatact attgaataca atataaaaaa
     3001 atcatttggg agattaagaa ggtagaagtt aagaacagat tttaaggtat gttatgatta
     3061 ttagaattga ttttgtgaaa ttattattgt aatatttaat tatatagata aagaagcgga
     3121 gtgataacta tgtgtttaaa aaaattatca aaattagagt tagttattat gaaatttatt
     3181 tggaatttag atataaaaac caattcatat gagattattg attatatgaa agaagaacat
     3241 aatttaccag aaaaagtagc tttaaaaact ttatcaaaac tatcaaagaa aagattctta
     3301 tatgttcaag aaacaggcaa gtgtatgtat tatacagttg caatcaaaga aaaggcatat
     3361 ttagagttta tatcaagaaa tgtgcaaaat cttttgaaga ataattttat aaggaattta
     3421 ttagtatcat ttcacgaaga ggagctaaca gaggaaaaga taaagtcgtt agaaaactgg
     3481 gtagtaaatt gggaagaagc ttatgtataa atgttattat ttttattaca atttagataa
     3541 ttttggtttt gtaagctctg caactatttt tagatggttg cagagtttat ttttattttt
     3601 tattccctta agcaatactt aaaagtaaac gcatttatat ttactaactt caattacttc
     3661 taatacttaa attgcttttt aaaaatattt tgatatgtca tctctatagt aatctagaac
     3721 ttgtttctat tctttatata aagtttttat gaatgatata tataatattc gttcatttga
     3781 ttaaaaataa caaaatatta aataattcta ctctgatagt ttgttaaaaa aataataaaa
     3841 aatattaata aacaaaaaaa aaatatctta agagaggaga atgttctaaa atataaaaag
     3901 gtttctagat ttcataaaag atactatttt agtcttgaaa atatttagtt taaaaagatt
     3961 ttaatt
//
LOCUS       DAGQVA010000148         3937 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.153, whole genome shotgun sequence.
ACCESSION   DAGQVA010000148 DAGQVA010000000
VERSION     DAGQVA010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3937
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.153"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            445..966
                     /locus_tag="MIV85_003707"
     CDS             445..966
                     /locus_tag="MIV85_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBY2963002.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDASFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            942..2528
                     /locus_tag="MIV85_003708"
     CDS             942..2528
                     /locus_tag="MIV85_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963003.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYPIIWYH
                     NKGKNNDIEFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKALDKILID
                     RNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKILIAKRS
                     DNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQPIPLAI
                     YQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENTVPDFKE
                     TLKLAFKKLNENQLQESTNM"
     gene            complement(2592..3110)
                     /locus_tag="MIV85_003709"
     CDS             complement(2592..3110)
                     /locus_tag="MIV85_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963004.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(3276..3638)
                     /locus_tag="MIV85_003710"
     CDS             complement(3276..3638)
                     /locus_tag="MIV85_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963005.1"
                     /translation="MEDLCMDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRA
                     ANNLHELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDI
                     IREYETYRGRYLTFNWKR"
     gene            complement(3719..>3937)
                     /locus_tag="MIV85_003711"
     CDS             complement(3719..>3937)
                     /locus_tag="MIV85_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2963006.1"
                     /translation="KILANVLSWGYSPSKVLVCDIKDYVPGQTENLYVVGGGACEKIS
                     SITKEKFIMIKGNDRFDTLYKALDFINR"
BASE COUNT         1543 a          521 c          462 g         1411 t
ORIGIN      
        1 ttatgtttta gtatgataat tttcgttcgt tttattatta caacttctac tatagttttc
       61 atactttaac atcaactaaa tgaatttaat taagattact agttaatcgt tttttggttc
      121 tttcatattc tgaaatctaa aattttatta tttgtttatt gttattattt aacacatgtt
      181 ggtatttcaa cgatttatct tattgttaat attcttattg cttccaaagt atatctaatt
      241 atttttaaga taatttacta atttttattt tttcaaacat acattcgaca aaaaacagtt
      301 tttatatggt ataattatat tgtataatac aaaaggttaa tgaaaataat taatattaaa
      361 tgtaccaaaa aaaatagttt ttgatataat gaatattata ataaataatt atttaaataa
      421 aatattatat aaggatgtga ttttatggat ttcaaaatca gagagctaat taatgatata
      481 acccaagata ttatccaaac atacaaaatc caaattccaa tagtaaatat aaatcaagtt
      541 gttgatgctt taggaggcaa ggtaatagaa gatagttctt taagtggata ctctgatgga
      601 tttattagaa aagttgatgc ttcatttgaa atagtggtat ctccttatca accagatacc
      661 agaaagaatt ttaccattgc tcatgaactt ggacatttat ttttacacat gggttatggc
      721 attgatgatg aactatggaa tagtcaagat ggaaatcagt attttagaag tggcaatacc
      781 aataaggagt atcaatccaa tgaatttgca gcagccttgt tgatgcctaa acatgaatat
      841 aaaagaatta tggatgaaaa cacagtaggt aataaggtcg acacttcaaa aattgcagaa
      901 tactttaatg tttcctctta tgcagcatct aatagaggga aatggttagg atatttacaa
      961 tggtagatga taaagaatat aaaactcaaa atgtaaataa tgttcataat tcagctaaaa
     1021 acgaaaacgc ttttaatctt aaaaagtata aggaaaaact tcaagaaaat attaatactg
     1081 atatttatga aaaagaaaaa gaacctaatc atccagaagt gattttgttc ttttcttttg
     1141 atatagctaa ttcatcatta tataaaaata taaattatag cggatgggct aaggtattat
     1201 cacatataat tcgtaagtta caatatagag tttatgaaaa ccttaaagca caactttgga
     1261 gagttcttgg tgatgaggta attttcatta tcgtactaaa aaattatgat gaaatttata
     1321 aatacataga tataatcttt gatattttaa caagcactgc taaagatata aaaagtggta
     1381 atatattctc tacactagaa ggattttctg aatctgaaaa atacttaatg aaacttcaaa
     1441 atattatttc attaaaagga gcggcctgga ttgctatagt atcaagaaat cctaatttta
     1501 atgctttaga aaataatgaa caatatgaaa atatttctgc tatgtacgat ttatccaata
     1561 attataaaat atttgagttc ttaggaaatg atattgatgc tggtttcaga atatcaaagc
     1621 aaacatgccc agaaagactt gttcttagtt ttgaactagc ttatatatta tcaagaaaaa
     1681 ctgatatttt atctaaatta catataatta catataaaaa attaaagggt atctggaaag
     1741 ataaactata ccctatcatt tggtatcata ataaaggaaa aaataatgat atagaatttg
     1801 atgatagttt ttcttttgat gaaatagaag aaaatgaatt ggttcgagaa tattttttta
     1861 ataaaaaagg agaaagtaaa ttactaattg attcttttat gtttaattct gtagacaagg
     1921 ctttggataa aatacttata gacagaaacc ttagtgataa gattgaaaaa ataggtgacg
     1981 taatttctaa aacaaacccc agttatgata aaaatacaat agataaagac tatataaaag
     2041 tagatttaat ggaattacac tgtgttgcgg tttgttataa taaatcaact tcaaaaatat
     2101 taattgcgaa aagaagtgat aatagaaata ataatgcgag taaatgggaa tttggttgtg
     2161 ctaaggcaag tctagaaact tcaattataa atactattaa agatgaatat gaaaaagatt
     2221 ttaatataaa cattgaacct attactgatt gcacaagaaa agatgattgc caacctatac
     2281 ctctagcaat ttatcaagtt aaaaaaagtg atggtttaca caaaggcatt ataactctcg
     2341 cagaaataat aaatgattat gatatttcta aatttgaacc cacatcaaaa cataatgaac
     2401 ttgcatggat aggagaggat gaacttgaag attttaatga aaacacagta cctgatttta
     2461 aagaaacttt aaaactagca tttaaaaaat taaatgaaaa tcaattacaa gaatctacaa
     2521 atatgtaaat agtattcttc tatgatttga ttctatcttc atagaggaat actaaccaaa
     2581 taaaacattt tctaaatagc attaaaaact actacaagta tatatataaa caatataata
     2641 ccacctaaaa taaaagcttc tactgacttt tttacattat acattttctt atcacagatt
     2701 aaagataatt cttttatttg aacaagtgca tcattaatca agttttcttc gtctttaaat
     2761 gcattttcaa atgcttcttt gtactgttca ttatttaaag atgctatctc tttataataa
     2821 aaaatagatt tatattcatt ttctatttta gaattccttg gctttaaaac cataatcgaa
     2881 aaataaattg aaataacaaa tatacataat ataacaatgt aaaatagcat ctctaaacat
     2941 ctgatattac ttatacttaa gtgattcatt attttttcct tccctgaaaa taaaaaacct
     3001 ataattgcgc tatttaataa tagtaaaaaa ctagctttat tatctgattt ttcaatatag
     3061 taatcaattc tatttactat aaacttcgct atgtctattt ttttatccat gattttacta
     3121 cctcatttca ttaaatttta tattgattca aaattttatt ttctacttat tatcattgaa
     3181 taaattatta tttggaaata atcttattga aataataaaa atatgtgaaa gaaagtaata
     3241 actaactata attactactt cctaacttaa acattctatc tcttccaatt aaaagtaaga
     3301 tatcgtcctc tataagtttc atattctctt ataatatcca atatttcctc cctagaagtt
     3361 gcaattaaac ttctatcaaa tagttcaatc attctattgc tatcattatc agaaacatta
     3421 caagactcta atatctcatt attaaatatt gcaatagcat acccagtacc tatttttatc
     3481 tcatttaatt catgtaaatt atttgctgct ctaaagatat cagcttcagc caatccacct
     3541 aaatcttcgc ttctattaat caagttatta agtttaatac taaaagctgc tcttacaaat
     3601 ctctcataaa ccaatgcatc catacataaa tcctccatta tcacaataat atatttacat
     3661 tatattacaa taatagagtt atcacaacaa acaaccactt ctagttgata acttttatct
     3721 atctattaat aaaatccaat gctttataaa gtgtatcaaa tctatcatta ccttttatca
     3781 taataaattt ttctttagta atagaactta tcttttcaca tgcgccacct cctacaacat
     3841 ataaattttc cgtctgacct ggtacgtaat cttttatatc acaaactaaa actttgcttg
     3901 gactatagcc ccaactaagc acattcgcaa gtatctt
//
LOCUS       DAGQVA010000149         3805 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.154, whole genome shotgun sequence.
ACCESSION   DAGQVA010000149 DAGQVA010000000
VERSION     DAGQVA010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.154"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            202..1026
                     /locus_tag="MIV85_003712"
     CDS             202..1026
                     /locus_tag="MIV85_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBY2963007.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            1155..2420
                     /gene="gluD"
                     /locus_tag="MIV85_003713"
     CDS             1155..2420
                     /gene="gluD"
                     /locus_tag="MIV85_003713"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBY2963008.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            2633..3223
                     /locus_tag="MIV85_003714"
     CDS             2633..3223
                     /locus_tag="MIV85_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBY2963009.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFICIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            3553..>3805
                     /locus_tag="MIV85_003715"
     CDS             3553..>3805
                     /locus_tag="MIV85_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBY2963010.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVS"
BASE COUNT         1532 a          351 c          669 g         1253 t
ORIGIN      
        1 aaagtaaaat tttttcaata aattttttat ttaaaggaaa tttatttttt gtaaagaaat
       61 ttcatgttgt agtatatttt ttgcttataa attttggtac tggatataat attaaactgt
      121 taatgatata ataaatttaa tctataaagt aaataaaatt ttgtaataaa tagttaaagc
      181 tattttataa ggagatatat gatggaagta tatgctttgg ttgggtcaag tggcacaggg
      241 aagagcttta aggctttaga gttcgcatat gaaaatgata tagaatatat aattgatgat
      301 gggattttaa tatacaaaaa caaggtttta gctgggatat cggcaaaaca agcaaatact
      361 actatagaag cagttaaaag ggctattttt tataatctgg agcatagaca agaagttaga
      421 gaagcaatta aaaaagaaaa tataagaaaa attcttatta ttgggacatc aaaaaaaatg
      481 gttaatcaaa ttgtagagag attgtcaatt ggaagggttt gcaagtttat aaatatacaa
      541 gatataagta ctaaatatga aatagaaata gcaaaacaag ctagaaaaga aggaaatcat
      601 gtaattcctg ttccagcagt tgagataaaa agtatggcaa gtggtcttag tataaattct
      661 ttgaagagac tttttagaaa aggaaataat aggaatatgg tagttttaga aaaaacaatt
      721 ataagaccaa cttttagtta tataggaaag ttttatatta gtgctgatgt aattaaacag
      781 attattgaat atgaagtata caactttgga agcattgata gaataaataa aatcaatata
      841 gagaattgca ataattttat gaatattttt gtaagtataa atatcaatga tttagaaact
      901 ataaaaaaaa ttgaagacat acaacagaca ataaaaaagt ctattgagaa aatgacttta
      961 gttaatgtac aaaaaataga tattaacatt cataaaatta aaaaaataaa cttcctccaa
     1021 tgttaaaaaa taaactgaga aaatgatata ctaatttgca ataaagtgtg ctataattaa
     1081 actgtaaatt taggaaatgg ttttttctaa atggagtata cataattata acgtatttat
     1141 aagggggctt tcaaatgtca ggaaaagatg taaatgtctt cgagatggcg caatctcaag
     1201 taaaaaatgc atgtgataaa ttaggtatgg aaccagcagt ttatgaatta ttaaaagaac
     1261 ctatgagagt tatagaggtt tcaattccag taaaaatgga tgatggttct ataaaaactt
     1321 ttaaaggatt tagatcacaa cataatgatg cagtagggcc aacaaaaggt ggaataagat
     1381 tccatcaaaa tgtttcaaga gacgaagtaa aagctttatc tatatggatg actttcaagt
     1441 gttctgtaac aggtatacca tatggtggag gtaaaggtgg aataatagta gatccatcaa
     1501 ctttatctca aggtgaatta gaaagattaa gtagaggata catagatgga atatataaat
     1561 taataggtga gaaagttgac gttcctgcac cagacgtaaa tactaatggt caaataatgt
     1621 cttggatggt tgatgagtac aataaattaa ctggacaaag ttctataggt gttataactg
     1681 gtaagccagt tgaatttggt ggttctttag gaagaacagc tgctactgga tttggtgttg
     1741 ctgttactgc aagagaagct gctgctaaat taggaataga tatgaaaaaa gctaaaatag
     1801 ctgttcaagg tataggaaac gttggttctt atacagttct taactgtgaa aaacttggtg
     1861 gtactgttgt agctatggct gaatggtgta aatcagaagg ttcttatgct atatacaatg
     1921 aaaatggttt agatggtcaa gctatgttag attatatgaa agaacatggt aacttattaa
     1981 acttcccagg agctaagaga atatctttag aagagttctg ggcttcagat gttgatatag
     2041 taataccagc tgcattagaa aactctataa ctaaagaagt tgctgaatct ataaaagcta
     2101 aattagtttg tgaggctgct aatggaccaa ctactccaga ggctgatgaa gtatttgctg
     2161 aaagaggaat agttcttact ccagatatat taactaatgc tggtggagtt acagtttctt
     2221 acttcgagtg ggtacaaaac ttatatggat actactggtc agaagaagaa gtagagcaaa
     2281 aagaagaaat agctatggtt aaagcatttg aatctatttg gaaaatcaaa gaagagtaca
     2341 atgttacaat gagagaagct gcttacatgc attcaattaa gaaagttgct gaagctatga
     2401 aattaagagg atggtactaa gatttactct taataaataa taggatataa ttatttaaga
     2461 tataaagggg ctgtacatag tacagccctt aaattatgtg gcttacaatg aagtaagcta
     2521 tttttgtttt aacttataaa taacttgata aattatgtaa tttagaatgt attttttacc
     2581 accacatgat tacaaattag aggagttaga ttgaattttt agacatgaac ttatgcattt
     2641 taaaagcaaa gaccttaatt taaagtatct agtattattt ttaaaaatag tatattggtt
     2701 taatccattt atatgtataa tggaaaaata tatggatttg gattgtgaac tttattgtga
     2761 tgagagagtt ttaaaaaatt gtactgtaca acaaaagcaa gaatatgctc taactattgt
     2821 aaattcaatg aaaagaagta caaatttttc aaataaattt gtagctggat taaataaaca
     2881 atctgatatt agaaaaagag taataaacat gttcagtgaa aaacataaaa atggtatctt
     2941 aagggctttg attataagct tgttttcttc tattacattt tttaaattcg attcaactag
     3001 tattattgaa gagaatgatt tcttagagag gtcaagatat acgtttgaag gaaggcaaga
     3061 agacatgttt gtaacaatag attttatata tgcagatgta cctataaaac ttagaaaaga
     3121 gcatgaagaa aactgtagag tcaatggaat agtaccaaaa gattcagatt caatagaaat
     3181 tattcctaga ttttataaag attgtatgga tttaaaaaaa taagttagac ttaatattga
     3241 tgttgatatt atgaattttt tatatttaag caattgaaaa ttttattata gattcaattt
     3301 tatatgtgtt taagtatgaa atttatagat agttgaaata attaaatatg attgatgcat
     3361 aggaatcatt actaagctat aattaattat aggggagttt aaataaatta tgagttacac
     3421 aatcataaaa tgataaaaat agttatctgt tacaaaaaat gtatcttttt aattaataaa
     3481 gataatatga aaacttaaaa ggcaaataaa cttaaatata aaatactctt aaataagata
     3541 ggagaaaaat gtatgtctaa ctttattcta aatgggattt ttagaacagt tatagtaagt
     3601 agtctaagca ttcttctgat attgattttc aagaaaaatg tatttaaaag atttagcaaa
     3661 aaatttaatt attatatatg gatgatagtt gttattaaat tatttttacc atttacatat
     3721 tatactttta caataaatat cttgagaagt aaaaaacaca ttaatattaa taacataaat
     3781 ttagagggat ttaataatgt ttcaa
//
LOCUS       DAGQVA010000150         3772 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.155, whole genome shotgun sequence.
ACCESSION   DAGQVA010000150 DAGQVA010000000
VERSION     DAGQVA010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3772
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.155"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            140..334
                     /locus_tag="MIV85_003716"
     CDS             140..334
                     /locus_tag="MIV85_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBY2963011.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(436..945)
                     /gene="vanZ1"
                     /locus_tag="MIV85_003717"
     CDS             complement(436..945)
                     /gene="vanZ1"
                     /locus_tag="MIV85_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HBY2963012.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1265..1654)
                     /locus_tag="MIV85_003718"
     CDS             complement(1265..1654)
                     /locus_tag="MIV85_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2963013.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEGDIDD"
     gene            2046..2402
                     /locus_tag="MIV85_003719"
                     /pseudo
     CDS             2046..2402
                     /locus_tag="MIV85_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2712..3029
                     /locus_tag="MIV85_003720"
     CDS             2712..3029
                     /locus_tag="MIV85_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963014.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
BASE COUNT         1470 a          440 c          425 g         1437 t
ORIGIN      
        1 ctataacctt tattttttta ttaaaatgca ttataataaa aagtaaatct aaatttgata
       61 cagttttaac aatcattatt ttcagaaaag tgatactatt gaatatatta agaataatta
      121 gagatggagg aactaagata tgagcgtaat tgtaatgtgt agtcgttgtg gaaaagaaat
      181 agataaatat agaaataaat atataactta ttatgagaaa aataccaatg cagaaattaa
      241 agtttgtata aattgtgcgt tagatttatt agaaaaaaca agagaaaatc aagaattgaa
      301 catacaagag tttcaagata caataattct ttaataattt aggaaagcac ctgtataggt
      361 gctttttatg tgtaaataat tttatatgta actgtatctt acgttctatt ttaagctaaa
      421 catatatact tatttctata agtttgcaaa aataactaat cctaaaaata atacaacaat
      481 aattgtcaca atcaatgcca atacattgat aatttttatg gtattattct taaatatttt
      541 cgataatagc ataaaaacag ctattcctat gattcctcct agtgtgtttc ctatcaaatc
      601 cgttatatca cttgcaccta gtgcaaatat atattgaagt gtttcaaatg ccaaactagt
      661 tataaaaata ggtataactt tttttataaa gctccattct tcttttagca tacacacata
      721 tatcccaaat ggtacaaata tagccacatt taatataatc tctgatatat ctactctatt
      781 attaattata agtgacccag caaaaggtac taagtttatg cttctaagat tcatggtttc
      841 aagggatgaa atatcaaatt gcaacttgaa tagtattatc catgttaaaa taattatgta
      901 aactataaat aatccttttg taatattatg ttttctagat ttcatttatt acctccttac
      961 tatatcattg tattatttta ttaatacaat gatatagtaa ggtaatttat ctgtcaacta
     1021 tttcttctaa aattatattc cttttataat ttcaatatct ttatcatatt tacatgattt
     1081 aagctattgt agtatttcat atatctttaa attttaattg gtattattct ctatattttt
     1141 tactatcaaa cactaaggaa ataatcactt ttctttatat aatgttctac catcacataa
     1201 aactaacatt aaatcaaaac gctactctca attgtctcaa actaaaaaga tactgataac
     1261 tttattagtc atcaatatct ccttctttca aatttttaaa gtattcttct aacttgtcca
     1321 agctcttact atctaaaact tcatcatcat gtaatgctga aataaaactc ttaaatgaat
     1381 tgttatgcat aaaactaaaa aaactctttg tctcaacttt taagtaatct ttctctttta
     1441 tagctatagt ataatgcgta catctatcta ccttatcagt agttaaaaag cccttatcta
     1501 ctaaattttt taaaaatgtc aatgttgtgc tctttttcca atcgtatttc aacttcatgt
     1561 cttctatgat atctcttgag gctaatacat catctactcc ccaaatatac ttcattagtt
     1621 ttagttctgc atgtggtaat ttattaatct tcattagttt acacctctta ccaatttatg
     1681 tataactaaa ctttataaca ataagtgtat ataatcaatt agattggaat aaatataaat
     1741 tccaatttat tctatataaa aataattaat aaaaaagaag tactctactt tagagagtac
     1801 ttttggatta tatattcaaa aatttatcta acatgattag agtatgtttt atgctttagt
     1861 gtgataattt tagttcgttt tattattata atatgtatta tatttaataa aatctataag
     1921 cttaaataca ggatatttat ttcatatact taatttatat taagttttat tgtatgtatt
     1981 attaagtttt actatatttt ttattaatat ttaatatagt taatttttaa taattatatt
     2041 atacaataac aatatataag ctaattaaaa accttaagaa gaacgatatt gacactactt
     2101 gaattatatt atagaaaagc tgaaataaat aaaatagttt gggctagaat aggttttaat
     2161 ttatatcttt ctaaaggagt tgcattaact ttaactgatg ctggtatagg gatttcagga
     2221 cttttggctg gtgctattcc tggtatagga cagtacttgc cacttatagt tagattaatt
     2281 acaatgtacc ttgagtcaaa tataacatct ggaaaaatct ttaaatttaa aaaatacgtt
     2341 ataataaagg aggtgcttgt gtaaccaaat actacttaca atctgtagaa atcaataggt
     2401 gataaaatga ttataaaata tctacttttt gcaattgttt cagcattaat tttattattt
     2461 tgtaataaag cattccaact aagtaaatta cacaagttca ttatattgtt tgtttcattt
     2521 tttatactaa cttttgtagc atcattcatt agtagataaa aaataagatg gtggggttaa
     2581 cttaccatct ttttctcatt taatatttgt aatattttag atactcttta tacttgtgtt
     2641 actgttatac tttgattagg aaaattaata caacatgagt tgatgattat attataaagg
     2701 aggtatcttc tatgaatttt aggaatattt atcttatact tatgggattg ggaattataa
     2761 tattaactac aataatatct ttaattgaaa ttaaaattgg tttttgtaat gaaaaatatt
     2821 ttaataaatt agaatcaaaa tatggaaata tagatagaaa aagaactatt aaactagaag
     2881 tactttatcg atatgtaaca ggttttgaat atatagcaat aggattattt acaaaaagat
     2941 tagatattac aataatagca ataatattag tagctactat aacagtaata ttatattact
     3001 tagttagaaa gagatatata actatataaa atctaataga attaatatca aaagaaggta
     3061 gcaactaatc accagcaatt aaaataattt gtttttcaaa gttaataaaa gtcttcttta
     3121 tagcaatgat ttaaatataa tcaaatatcg taacggagat ttttttatga ataatttaag
     3181 aaaacaatta atcaaagaaa ttatataaga tggagaactt ataaaatcta cagatataag
     3241 tagttttagg agtaaacaca gatgacttat ttcaaagaga caatagctac aagttatcct
     3301 cattctgtaa tacaaaaatg tttaatacat tagataagaa atactttaaa tatgtttcat
     3361 acaaggactc aaaagaatta ataagtaatt ttaaatctgt atataggtca gttaatgaat
     3421 aagaagcctt atcgacttta gataaaatag attaaaaata atgtaaacag tatacttcag
     3481 aaattaaaat tttgggaaat aactggaatg ttgtagcatc atcctttagt tttactaaaa
     3541 taagtaatat ctataatata tattacaagt ataatcgaaa gatttaataa atatttcaaa
     3601 aatgtctcaa aaacaaagtc cagatttaca tcaaacgctt cactcttaaa gatattattc
     3661 ttgacaagcg aaaatgtgat gaaaaaatgg actatgaaat ataaaaattg atataatata
     3721 tacaatcatt tattcatatc ttttgatagt agaatataat tttaaaaatt at
//
LOCUS       DAGQVA010000151         3686 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.156, whole genome shotgun sequence.
ACCESSION   DAGQVA010000151 DAGQVA010000000
VERSION     DAGQVA010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.156"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            261..620
                     /locus_tag="MIV85_003721"
     CDS             261..620
                     /locus_tag="MIV85_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2963015.1"
                     /translation="MKLRESYTCPLELVHDIIKGKWKTIIIFQLRNGKCSFSELHHSI
                     AGITQKMLLEQLRELKHFGLIDKKTYDGYPLKVEYFLTGQGEKMLSAIKIMQEIGIDY
                     MVEHGMTEILDEKGICY"
     gene            710..1261
                     /locus_tag="MIV85_003722"
     CDS             710..1261
                     /locus_tag="MIV85_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBY2963016.1"
                     /translation="MKKALLIIDVQNDYFPNGKCQLYKPEIALNTIKDLLKIFRKQNL
                     PIIYIRHESIHGTFFNPNTNGVQIHNDIKPLDTETVIVKHYPNSFYETNLQNKLVEIE
                     VTKLVVCGMMTHMCIDTTIRAAKDYGYEITLISNGCATKELKWNGVNIPADTVQSIFM
                     ASLNQKFANVITSTEFLSNEITR"
     gene            1245..1610
                     /locus_tag="MIV85_003723"
     CDS             1245..1610
                     /locus_tag="MIV85_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009291267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2963017.1"
                     /translation="MKLRDEYTCPLELIHDMIKGKWKPIILWRLRLGATSLSKLENDI
                     DGITQKMLLEHLKELIDYGFVDKKTFSGYPLHVEYFLTEDMGNQILEALRIMQHIGIE
                     YLRKNGMENELTEKHVIPD"
     gene            1698..2198
                     /locus_tag="MIV85_003724"
     CDS             1698..2198
                     /locus_tag="MIV85_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBY2963018.1"
                     /translation="MYISSIGISNGIIEKKYGSHGVQFNENDVPTYSIPFKIENAPDK
                     TVSFAFILEDKDAYPVTGFIWVHWLGANLTRSELKENESQTAKDFIQGANSWTSILGN
                     QQTREQTSCYGGMAPPDKAHIYELHVFALDKLLDLKNGFYLNELYQEMEGHILEEAVL
                     KGLYEK"
     gene            2188..2703
                     /locus_tag="MIV85_003725"
     CDS             2188..2703
                     /locus_tag="MIV85_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBY2963019.1"
                     /translation="MKSKPVKVGLRTIKTVLSAFLCFLIDSLRASSVPFYAVIASILC
                     IQPDMENSLSVAKNRELSTIIGGILGMLFLLMERIFLPIQPEILRELTLSILLIPIIN
                     LSVLLKQKKGTFLTCVVFLCVTVTHEKDISPIWFAWNRIVDTSLGIGISLAVNSFPFH
                     KFKVGGTMGKY"
     gene            2697..2978
                     /locus_tag="MIV85_003726"
     CDS             2697..2978
                     /locus_tag="MIV85_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBY2963020.1"
                     /translation="MLIVEFTEKEDAVFQQAVEWLSSKLAYTPASFNQQKKGFDIDPL
                     TRTFTNEEGTSIYLTAKEFDLLYFLSSHKGQVFTKEQIYEKVWGYDNFY"
     gene            3346..3570
                     /locus_tag="MIV85_003727"
     CDS             3346..3570
                     /locus_tag="MIV85_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963021.1"
                     /translation="MIGIKKRDIKKALKAGAKAGGSSYADVLADIEATIDEVMNSTDP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTRV"
     gene            3592..>3686
                     /locus_tag="MIV85_003728"
     CDS             3592..>3686
                     /locus_tag="MIV85_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2963022.1"
                     /translation="MKNEMWVLCPICNNKTRTKVREDTELINFPL"
BASE COUNT         1329 a          501 c          721 g         1135 t
ORIGIN      
        1 ttccccatag aataccttat cgcctaaatc attacgagaa agcccagctt tttcacgggc
       61 ttctctgatt gccagcccta gcggtctgaa atcaaaagta tgtgtttctt ttgtttttct
      121 cattttaaat caccatacat gagtttatac ttcatggttc gtatttagaa tgtgttaaaa
      181 gtgcatatat tagggtaata aaatatgttt tgaaatattg agcttaaaca tgtaagatat
      241 ttcacatagg agatgataaa atgaaactta gagaaagcta tacatgtcca ttagaacttg
      301 ttcatgatat tataaaggga aaatggaaaa cgataattat ttttcaactt agaaatggaa
      361 aatgctcttt ttccgaactc catcacagta tagcaggaat tactcaaaaa atgctattgg
      421 aacaactgcg tgaattaaaa cactttggct taattgataa aaaaacatat gatggatatc
      481 ctctaaaagt agaatacttt ttaactggac agggagaaaa gatgctatca gcaattaaga
      541 taatgcaaga aattggtata gattacatgg tagagcatgg tatgacagaa atccttgatg
      601 aaaaaggaat ttgttattaa actctatcat atacacgaaa aagtaagtaa tttacttaga
      661 aactattatc ttatattatt taattagaat taagagagga tatgagagta tgaaaaaagc
      721 attacttatt attgatgtgc agaatgatta ttttcctaat ggaaagtgcc agttgtataa
      781 accagagatt gcgttgaata caataaaaga tttattgaaa atttttagaa agcaaaactt
      841 gccaattatt tacattcgcc atgagtctat ccatggaaca ttttttaatc caaatacaaa
      901 tggtgtacaa atccataatg atattaaacc attagataca gaaacagtta ttgttaaaca
      961 ttatccaaat agtttttatg aaacgaattt gcaaaacaaa ctggtagaga ttgaggtaac
     1021 gaaattggtt gtttgtggaa tgatgacaca tatgtgtatt gacacaacta taagagctgc
     1081 caaagattat ggctatgaga ttacactaat atcaaatggt tgtgcgacca aggaattaaa
     1141 atggaatgga gtcaatatcc cagcagatac agttcaaagc atatttatgg cttctttaaa
     1201 tcagaaattt gctaatgtta ttacaagcac ggagtttttg tcaaatgaaa ttacgagatg
     1261 aatatacatg tcctttggaa ttaattcatg atatgataaa gggaaaatgg aagccaatta
     1321 ttttatggcg cttacgatta ggtgctactt cattatctaa attagagaat gatattgatg
     1381 gaattacaca aaaaatgctt ttggaacatt taaaggaact tatagattat ggatttgttg
     1441 ataaaaaaac attttctggt tatccacttc atgtcgagta ttttttgacg gaagatatgg
     1501 gaaatcaaat actagaagca ttacgaatta tgcaacatat agggattgaa tatttaagga
     1561 aaaatggaat ggaaaatgaa ttaactgaga aacacgtgat tccagactaa tacctacaaa
     1621 aaagtgggta atttacgttt tgcttcctct ttgttaatat atatctgtaa ttaaacgata
     1681 tacaaggagg aaaatttatg tatatttcaa gtataggaat ttctaatgga attattgaaa
     1741 aaaaatatgg tagtcatgga gtgcaattca atgaaaatga tgtgccaacg tattcaattc
     1801 cgttcaaaat tgaaaatgca ccagataaaa cggtttcctt tgcctttata ctggaagata
     1861 aagacgcata tccagtgacg ggttttatat gggtgcattg gttaggagct aatctaacaa
     1921 gaagtgaatt aaaggaaaac gaaagccaga cagcaaagga ctttatacaa ggtgcgaata
     1981 gctggacaag catattgggg aatcagcaaa ccagagaaca gacaagctgt tatggtggaa
     2041 tggcaccacc agataaagca catatttatg agcttcatgt atttgccctt gataaactgc
     2101 ttgatttaaa aaacggattt tatcttaatg aactctatca agaaatggag gggcacatcc
     2161 ttgaagaagc tgtactaaaa gggttgtatg aaaagtaagc ctgttaaagt tggattgcgg
     2221 acaattaaga cggtactttc tgcgttcctt tgttttttga tagatagctt aagagcttca
     2281 agtgttcctt tttatgcagt gattgcgtct atactgtgca tacagccaga tatggaaaac
     2341 agtttgagcg ttgctaaaaa cagggaactt tcaacaatta tcggcggtat actgggaatg
     2401 ctctttttgc ttatggaaag aatttttttg cccattcagc cagaaatact tcgggaattg
     2461 actttatcta ttttattgat tccaatcatc aatctgtctg tactgttgaa acagaaaaaa
     2521 ggaacatttt taacgtgcgt tgtattctta tgcgtaacag taacacatga gaaagatata
     2581 agtcctattt ggttcgcatg gaataggatt gttgacactt cattagggat tggtatttca
     2641 ctggcagtaa actctttccc ctttcataaa tttaaggtag gtggtactat gggaaaatac
     2701 tgattgttga atttactgaa aaagaggacg ctgttttcca acaagcggtg gaatggctgt
     2761 cctctaaact tgcttacacc cctgcttctt ttaatcagca gaaaaaagga tttgatatag
     2821 acccattaac ccgtaccttt accaacgaag agggaacgtc tatatatctg actgctaaag
     2881 aatttgacct actatatttc ctttccagcc acaaaggaca ggtgttcaca aaagaacaga
     2941 tttatgaaaa ggtatgggga tatgacaatt tttattagtc tggcaataat gaagaaaaaa
     3001 gaattttaga aaagtgaggt gtgcttatgg atttatctat tttggtagta gtattgatat
     3061 tgggtgtggg tattccttta agaaataagg caatcaaaaa atacagataa aatatgaaaa
     3121 agaaaggaaa aatgaaaaaa tatgaatatt tagaaattga ttatactgcg aaaggtgttg
     3181 tattcctttg caccgataaa cataaggaag ttataaatag ctatgcagaa aatgggtatc
     3241 gctatgcggg ttcgtgccta cagaaattga cgcaaaaggc tgtatgcgaa agatagattt
     3301 aatttttgaa aaagaagatt aacgtatttt agggagttgg ttcttgtgat aggaattaaa
     3361 aaacgagata ttaaaaaagc attgaaagct ggtgcaaagg ctggtggttc ttcgtatgct
     3421 gatgttttgg ctgatattga agcaacgatt gatgaagtta tgaacagcac cgacccagaa
     3481 gtgcaggcaa atttcaaaaa gtattttgga aataaacgcc ctacaccaga ggaatatatc
     3541 tataaaatca cgaagaaaac acgagtttaa agaattagta agggtggttc tgtgaaaaat
     3601 gaaatgtggg tattatgtcc tatttgcaat aataagacac gaactaaagt gcgagaagat
     3661 acggaattga taaattttcc tttgtt
//
LOCUS       DAGQVA010000152         3649 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.157, whole genome shotgun sequence.
ACCESSION   DAGQVA010000152 DAGQVA010000000
VERSION     DAGQVA010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.157"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            693..1445
                     /locus_tag="MIV85_003729"
     CDS             693..1445
                     /locus_tag="MIV85_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2963023.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKQLSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            1435..3546
                     /locus_tag="MIV85_003730"
     CDS             1435..3546
                     /locus_tag="MIV85_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2963024.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCTVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISVVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
BASE COUNT         1380 a          514 c          481 g         1274 t
ORIGIN      
        1 aaagtcttat ttattacagt tctttattat actacagact tttattatta caacatttta
       61 ttattttaac ttctttacta taatatagta atattttaat atctcaaaat catatcaatc
      121 acttttcagc atagtctaaa atacttccac tttctaaaat tatctatcat acctatacta
      181 ataatacttt ttaacctttt tattatacat ttcaattatt tttaacaacc tatttatttc
      241 caaaactcca atatattttc tcaattacat tgtgttaata gcccctaaat cctttcaaat
      301 tatttacaat acattctatt aaataatctt actgctctat aattcttttt ttctttttaa
      361 ccctactata cattatttac atcatttttt tcaatacaac attcgttatt ctataacctt
      421 tttactttta ctatatactt cttttctaac tacaccttca atgttccaca tcatattact
      481 ttagcacaac aattaatacc taaaaataac cctctaaatc ctccaataat ataatcaatt
      541 taactataat aataacctct cacactatcc aaacaatata ttttcaaaca ttacaaaaaa
      601 acatccaact attacaatat agctcatatc cctcctcccc tttcaaatgc tatcattgac
      661 ttacaagata aatgaaagtg aggatgatat atatgcttaa agtaaaccaa ttatgtaaat
      721 catataaaac aggcagtaaa acatatcctg tattaaaaaa tatttctttt gaaatcaaca
      781 aaggagaatt tgtcgcaatc atgggttcat caggaagtgg aaaaactact cttttaaatt
      841 gtatttcatg ttttatccca attgataatg gggaaataat tcttggaaat aataatataa
      901 gaaatttaaa agaaaagcaa ctttcagaag ttagaaacca acaactagga tttgtattcc
      961 aagatttcat gctatttgat ggtcttagtg tatttgaaaa tatatgtgtt ccacaaatta
     1021 tcaaaggtag tcaagtctta caaatggaaa accgtgcaat taatctatgt gagctatttg
     1081 gtattgaaca tatcagaaaa aaataccctg ccgaaatatc tggtggagaa aaacagcgta
     1141 cagcagtagc aagagcacta atgaacaacc cagatttaat attagcagat gaaccaactg
     1201 gtaaccttga tagtaagtct tgtcgtacag tcattgaatc atttttaaaa gcaaagcaag
     1261 aattagatgc tactatactc atggttacac acgatagctt tgcagcaagc ttctgtgacc
     1321 gagttattgt gcttaaagat ggaataattt ataaagaagt tgtaaaatca aattcaagac
     1381 ataaattcct agatgaatta ctagaagttt taaaagaaat gggaggcgct caagatgaca
     1441 attaataaat tatacagtaa acttcgagcc tataattgga agaactatac aactttattc
     1501 ttttgtataa tactttctgt ggtattagta acttcatatg ctctaattta ttttagccca
     1561 acaatacaaa acatacttcc aactggtgga gatagcagaa aacaggctac aatgatattc
     1621 tcagttgcta tattaggatg cactgtcttt actacatacg catcttccct ctttttaaaa
     1681 tttaaaagca aggaaattgg tattttcatg gctctaggaa cagataagaa gaaattaaaa
     1741 aaacttctat tttcagagat attgttaatt tcagtagtat gctgtttttt aggtcttata
     1801 ttaagtattc ctgtatcttt tggtatatgg aaaatatttc aattagtgat tattgatacc
     1861 agagaaatga catatcattt tggaactcaa ggattcatat atggatttat atttagtgta
     1921 tttgtgacat tatgcatatt tatactttct gtaaaattta ttaatcgtac aaatataatt
     1981 gatatattaa atgaccagag aatatctgaa ccaatacagg atgtaaagga ctggtatggt
     2041 atattaggta taatttttat tatactcggt atttttctag gatatctcgt accttcacta
     2101 actataaaca aattaaatta taaactacca tctatatgga gctttactta tctactctct
     2161 cttattggaa tatatatgat tatgacatac atagttgtac atgctaaaag aggaaaacat
     2221 ccagagaaat actataaaaa catcatatca actagcatga tgagatttat gggaagacaa
     2281 acagtaaaaa acatgtgtgt tatttcattt ttgattgcag gagcattatt tgctgtattc
     2341 tatgttccta atatggttac aggtatctat gatactctta aaaataaccc tatagattat
     2401 acttttacct acaatcaaag agataaacag gtatcaaaaa aagatattga acaattagca
     2461 gataaacaca atataaaaat tcaaaactat atggaaattc cttctataga attaattgtt
     2521 gatggtgtag aatcaatata tcataaagat ggaactatcg aaaaggtata tatgaaaaaa
     2581 agctcctatg atatgttctt taattctaaa gatttttcca agctaattgg caaaccaata
     2641 actataaaaa atggtgaata tcttgctgtt gtaaataaag gaaatgaaaa tcaagattat
     2701 aaatatacca aatttatatc aagcccagtc acagaaaaag aaatcccctt tagatatgct
     2761 ggaaaaataa tatttaatgg ttcttttttt caaaatagaa gtatgaacgc ctatgtcctt
     2821 aatgaggagg attataaatc atttactaaa gatttatcca taaaaaatta caataattct
     2881 atactattta atgtagataa agatacctat gcttttgcca atgacttaaa gaaagaaatt
     2941 ataaaaagaa catctaagga aatgggcatg ttcagtggtt atgatgaata cgtaaaaaaa
     3001 cgttatgaat caactggaag aaaatatttt atggatgaag aatatccaag tggtgaaggt
     3061 catttaaaac tagacccaaa caacaatcag ttgtatctta attggaaata ctatcctaac
     3121 tttaaaattt tacaaagcca agatatgata aaaaacatgg cagtcttctt aatgttattc
     3181 atatatgtgg caatcatatg ttttacagca gtaggaatca ttgcatatac aaggggtgtt
     3241 actatagcta taaatcacaa gcaggtcttt atggatttaa atcgattagg agcaaacaat
     3301 gattatataa agttctgtat tagaaatcaa ttaaagaaag tattttcata ccctcttatt
     3361 gcaggaagtt ttttaattta tctgtttaat tttatgatta tgttaaataa tgatggtaga
     3421 atcgtcaata gtgaggtcaa tgctcttttg ataaacttag gttttatagg gatttgtggg
     3481 gtttatatgt accttatata tctattaact tacaagaaat tcaaaaaaat tattggtatt
     3541 ttataataag gaaggttgtt agatttttaa agtaataaaa tcattggtgt tttataataa
     3601 aaaaggttat taggttttta aagtaataaa atcattggtg ttttataat
//
LOCUS       DAGQVA010000153         3384 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.158, whole genome shotgun sequence.
ACCESSION   DAGQVA010000153 DAGQVA010000000
VERSION     DAGQVA010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3384
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.158"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..172)
                     /locus_tag="MIV85_003731"
     CDS             complement(<1..172)
                     /locus_tag="MIV85_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963025.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGD"
     gene            complement(175..843)
                     /locus_tag="MIV85_003732"
     CDS             complement(175..843)
                     /locus_tag="MIV85_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2963026.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            complement(1129..1656)
                     /locus_tag="MIV85_003733"
     CDS             complement(1129..1656)
                     /locus_tag="MIV85_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBY2963027.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            complement(1873..3033)
                     /locus_tag="MIV85_003734"
     CDS             complement(1873..3033)
                     /locus_tag="MIV85_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2963028.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKNQINNINLF
                     FDENIILRVVENIISNAFRYARNNISILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYKDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            complement(3021..>3384)
                     /locus_tag="MIV85_003735"
     CDS             complement(3021..>3384)
                     /locus_tag="MIV85_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963029.1"
                     /translation="LDELGARISAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNN
                     QISLSKKEFDIVELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKH
                     TLENYIETVWGVGYKWIK"
BASE COUNT         1165 a          503 c          433 g         1283 t
ORIGIN      
        1 tatcaccatt aaaagaacgg gcttgttcaa ttcttaaatt ttgtaggata ccaattgact
       61 gtccaaccac agttgtcata atagttgata gtactattgc tataatgatg aatgtagtca
      121 taagtttctg gctttttaat tcttttattg aaagtgaaag gtaattcttc atttctattt
      181 cacctccata agaacaccat caataattga aatttttcta tcagcaagtt ttgcaattct
      241 atcatcatga gtaattacca ctaaagtctt tccaaactgt tttgaagttt ttataagaag
      301 attcataact tcactgccac ttttactgtc caagtttcct gtaggctcat cagcaaatat
      361 tatatctggt tttgcaataa gtgctctagc aattgcaact ctttgttgct gaccgcctga
      421 aagttcatgg ggaagatgat tgagtctatc tgcaattcca agtaatgatg aaatttcatt
      481 taaatagcct ttatcaggtt gttttttatc tagaagtaca ggcattgaaa tattttcaga
      541 tgctgtaaga acaggtaaaa gattaaattg ttgaaagacg aatccaaagg attttcttct
      601 aagtgcagat agttcttttt cagtgtgttt atatatatct ttatcatcaa gtaacacttg
      661 tccagaggta ggattatcta atccacttaa aatatgtaaa agtgtgcttt ttccacttcc
      721 agaaggtcca attacagaaa caaattcacc tgagtttatt tctaaattta cattattaag
      781 tgcgataact ttattgttat tagaaccata tatttttgat aattgttttg cttttataat
      841 cataaaaaac actctccttt tctatataag aagagtgtaa gttttaaaac tcaatttttt
      901 cccaactttt agcttaaatc taaaaagtct tcactatttg cggataattc gcagtgctga
      961 taagcagttt cagtatcatt tttaatttaa aatgtaattt atgcactaaa ggctttacaa
     1021 tacaactcta ttgctttaaa actattttac acataaactt gtggataatt ttttatgttt
     1081 tacttcctca ttattatata aattattttt gtcacaaatt ctaagttttc acataaatat
     1141 actttttata tcacgattta attcttttga ttttatcata attgctattt cttcaaaaga
     1201 agaaagaaaa gccacgatac atatcataat tcctgcaaca tcaagaccaa agcaaatata
     1261 gagtaatgga aaagcaaaga tagaaattcc agtgatttta ttcatcaaag tatgaagtga
     1321 tgaaaatgtg cgatacttaa aaaaaccaat actgtaacta atcaaccgta acaatgctat
     1381 tgcaacaata caccaccata gatacatggg aagagcaata ttttttccga cagtaaccaa
     1441 aattgtaacc gcaaaaatga aatcagcaat actatctaac tttgcaccta ttccactttg
     1501 ttgtctcaac tttcgggcaa taagaccatc aagtatatca ctaattccac accaaaaata
     1561 acatatccag aaaggcagtg aacagaatgt agaactaagc attagcaatg caaacacaat
     1621 acgagagaat gtaatattat tagcaaaact tttaatataa tcacctccaa aattctaatt
     1681 tcatactatt ctacatattt aaatatatat ttctattatt gtttcaaatg ccttttgcca
     1741 aaatattata attgaagcaa ctcttacaac ttctataaaa tagtatatat attggttgta
     1801 aattgaaata cattttataa attataaact aacaaagctt atataagaac agtgaaagct
     1861 tacaaaatca ttttaatttc ttgttgagaa tttagcagta attttagcac tgttagtaga
     1921 attattttca atagaaatag agccaccatg tttttcacat aatatttttg atatataaag
     1981 acccatacca aagtgtgcat tgctgtcatt taaagtctta tctttataga aaggtcttaa
     2041 agctaatttt agagattcct tactaaatcc tataccatca tcttcaatta caaaggtaag
     2101 gagttcttgt tcaagatata taagtatgga tatattattt ctagcatatc taaaagcatt
     2161 cgatattata ttttcgacga ctctaagaat gatattttca tcaaaaaata gatttatatt
     2221 atttatttga tttttaagtg taaaagattt tccttcttgt ttagcaatga tagatatatt
     2281 ttcatctaag ttttctataa acttgtttat attcgacata gattttgaaa caactaaatc
     2341 ttctaatcgt tgagcattac tcatattttc tacatagtat tcaattctgt taatatgctc
     2401 agacataagt tgtgtggttg ataaaatctt ctcatcacta agcttacctg ttggtatgta
     2461 ttttgttaaa tagtttgagt aaccttttag aactgttagg ggatttctta aatcatgaga
     2521 aaaagcagca ttaagttgtt ttctatcatt aatcatagtc cacatcttta tgttgttttt
     2581 atttagttca gacctcattt tttcaaaagc attacataga ttacctaatt catcattatt
     2641 attatactct aagcaaaagt ctaaattgtt gttggatatt tccattgcac ctttattgag
     2701 tatttctatg ggtgttttta attttacctt gtaaaaaatt atatcagcta ataataaaag
     2761 tcctataaaa aatataagtg gaagtacaag ctgaagtatg ttgattatat taagtaatgt
     2821 tttatcataa tcactaaatt ggttcacatt gttttgaact atggttataa tacctgtatt
     2881 tataggtgtt tttaaatact tatcttgtat agaattatat agattattaa gtaaaatgta
     2941 tgcgaaagta gtaagtactg atgctataat tagtgaagat aaagtaagaa caaagaaagc
     3001 tttttttaat gacatattat ttattttatc catttataac caactcccca gactgtttct
     3061 atataatttt caagagtatg ttttgatagt ttgattcgta tttttctaat gtgttccatt
     3121 ataacatcac tatttccatt gctattgtat ccccagactc tatcatatat tttttcttta
     3181 tcaaatacct gcccaggatt catagagaga agctctacta tatcaaattc cttttttgaa
     3241 agtgaaatct gattattata tatacaaatt aacctttttt cgtaatctat tgttaaatca
     3301 ttataaaatt taattttagt ttgatttgac tttctttgtt cacgtcttaa atgggcagat
     3361 attctagctc caagttcgtc taaa
//
LOCUS       DAGQVA010000154         3356 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.159, whole genome shotgun sequence.
ACCESSION   DAGQVA010000154 DAGQVA010000000
VERSION     DAGQVA010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3356
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.159"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(40..231)
                     /locus_tag="MIV85_003736"
     CDS             complement(40..231)
                     /locus_tag="MIV85_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963030.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            502..741
                     /locus_tag="MIV85_003737"
     CDS             502..741
                     /locus_tag="MIV85_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2963031.1"
                     /translation="MNYNLIKVIFSLFKKKSGYTFTNFLNKVRVEKSKKYILKKDLSI
                     LDVAVLIGFNSQNYYSIIFKKFNNFTPIEYKNIYN"
     gene            1050..2669
                     /locus_tag="MIV85_003738"
     CDS             1050..2669
                     /locus_tag="MIV85_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBY2963032.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDEHFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            3043..3237
                     /locus_tag="MIV85_003739"
     CDS             3043..3237
                     /locus_tag="MIV85_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBY2963033.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
BASE COUNT         1266 a          390 c          439 g         1261 t
ORIGIN      
        1 ttttataatc atacaaataa atataaacct cttttatgtt tatctatgtt ttaaatacac
       61 aaaatattct tctacttcat ctccattttt tacttttact aaatattcat tataatgagc
      121 attatatggc tgtgtcattt tgcattctat tacattttct atgtcttcta attctaaaag
      181 ttctacatcc tttaaaaatt ttctttctat gagttccatt aatctttcca taatatatcc
      241 tcacttcccc tataattaag ataaactata tatcctctta atgcagagtt tatctgttta
      301 ttatattata tccaatatat tacagtttct aacatcattc ataaattatt ttaacaaata
      361 gagattgatt ttttaataaa tatgccttga taaaatgaaa catagaccaa ctcttagttt
      421 tatgtaaaga aaacttaaag aaaactataa attatattca caaaaattac tcagaagata
      481 taacagtaag taatatatgt aatgaattac aacttaataa aagttatttt ttctttgttt
      541 aagaaaaaaa gtggatatac ttttactaat tttttaaata aagttagagt tgaaaaaagc
      601 aaaaagtata tattaaaaaa agacttgtct attttagacg ttgctgtact aattggattc
      661 aatagtcaaa attactatag tataattttt aaaaagttta ataactttac accaattgaa
      721 tataaaaata tttataacta aaaaatatca ttctaaaagg atgttatttt tttacatatt
      781 ttttacaatt atagttaatt ctttgttaaa ttgtttgtac ataaaatact aaaaatctaa
      841 gttcaagtat ttaaattgct atatatcata aattttctaa aattaacaac aacttaaaaa
      901 tttaacattc tcttaacgta tacttaacaa aacattaata tttttattga caaaatttgt
      961 tattctatat tatggaaaca ataaatttta gttaataaag tttataattc agataaaaaa
     1021 attattaatt tcttaaggga ggaaatatcg tgaatatagt aattagcctt atcggtggac
     1081 ttggactttt tctttacgga atgagtttaa tgggagaagg tttacaaaaa tcagcaggag
     1141 acaaattaaa aaaaattatt gaactcttaa caagtaatgt tgttatgggt gtactggtag
     1201 gtacagtcgt tacaggtatt atacaaagtt caagtgctac tactgttatg gttgtaggat
     1261 ttgtaaatgc aggtataatg aatctaagtc aagctattgg tgtaataatg ggggcaaata
     1321 taggtactac agttactgct caattagttt catttaatct tgaaggaatt gcaccaattg
     1381 ctttaggtat aggtatttta ttctatttat ttacatcaaa tcaaaaaaca aagcatttat
     1441 ctgagatact tataggtttt ggtatattat ttacaggaat ggagtttatg aaagatgcag
     1501 tagctccact tgctgaatac aaagcattca ctgatgcact tttatatttt agtaaaaatc
     1561 ctgtattagg tatattggca ggatttgcca taactggtat tgttcaaagt tcaagtgcat
     1621 ctatgggtat gttaatagca ctagcttctc aaggaatact tcctctatca tctgctttac
     1681 ctattcttta tggagataat ataggtactt gtgttacttc acttttatca agtgttggtg
     1741 caagtagaaa tgctcgacgt gcagctgtaa tgcatttaag ttttaatgta attggtacaa
     1801 taatatttat gcttgtttta aataaaccta tatcagccat agttactcat tttgacccaa
     1861 ctgatacagc tagacaaata gcaaatgcac atactttatt taatcttaca aatgttataa
     1921 tattattacc attttctaaa tacatagtta aattagcaaa tagacttata cctattaaag
     1981 aaactgaatc agaaatagta aataatacta agtacttaga tgaaaggatg tttagcactc
     2041 catctatagc acttggtaat actgtacaag aagttgtaag aatgggtcat aaagctacaa
     2101 actctttgga acattcaatt gcaggatttt taaataagag caatgaagat attaataaag
     2161 cttttgagtc agaaaaagtt gtcaataagt tacagaaaga tatattgaac tatttgttaa
     2221 aactttctaa agaacctctt agagatgatg aacactttag aacagatttg ctttttaata
     2281 ctgtaaatga cattgaaaga gtctctgacc atgcagaaaa tatagctgaa ttggccatga
     2341 gtgttaagga aatgaacatt agtttttctg atagtgcgat aagagaaata tacgaaatat
     2401 acaataagac aattactaat tttaaggatg ccttaatagt tttagatgtt aaagattttg
     2461 agttagcaaa taaagtttta gaagttgaaa atgaagtaaa ttatttagaa aaaactttta
     2521 gaaattcaca tatgattaga ctaaataatg gaagttgtac aattgatgct ggtgtacttt
     2581 atcttgactt acttactaat ctagaaagaa tttctgacca ctcaacaaat atagtaaaac
     2641 aagtactaaa acttaaacaa aaaatatagt gattattttt atatataatc ttaatcaatg
     2701 agaagtaaga agctatagat aatgcttata tcatttatgg tttcttattt tttatgtaat
     2761 actcaaattt ttatagtatt ctcttattat taaacaattt ctgcctagaa tattccatat
     2821 atatatgact tctttcataa aacttgaact gcccataact aaagtcacaa gtatacataa
     2881 ctatttttta atcaattata accaatattt gttttattta tcttcatttt aattcttcat
     2941 tcaataatgt aataagatta ttttttattt ggatactatt atatcatcta aatatgttat
     3001 tatatatttg gatattttca tattaatagg agggattcta caatgataaa ttatatggta
     3061 gaaattatat atagcgaaaa aataagcgaa gtagaaaaca tgttgaaaat tgaaaatata
     3121 caatatgaat ttacttctcg tgatggcttt atattttttg gtttttatga tatgacagac
     3181 gcatatagat ttgagacttt atgttcagat gaaaaaattc gatttaaaag aatataatag
     3241 ataaaaaagt acatatttct aaactatttg tttttcaaat ttaggttgtg ttttaatgta
     3301 gtgttgatat tataaacaat tttaataata aaaaagtagg gacattatat taatat
//
LOCUS       DAGQVA010000155         3138 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.161, whole genome shotgun sequence.
ACCESSION   DAGQVA010000155 DAGQVA010000000
VERSION     DAGQVA010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3138
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.161"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..657
                     /locus_tag="MIV85_003740"
     CDS             <1..657
                     /locus_tag="MIV85_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBY2963034.1"
                     /translation="FVSIIGSNGTGKSTLLNIISGLIKESSGQITLDSTTITNLAEYK
                     RTQIVSRVFQDPSLGTCPSMTVRENLSLALNKGKLLNLKKCLRHKTNDLEHLLEGISL
                     DLKKYLDIKVQYLSGGQRQSLSLIMSSLASPKVLLLDEHTAALDPKTSNEVIELTDKI
                     VREKNITTLMVTHNLKHALQYGDRLIMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV
                     "
     gene            754..1791
                     /locus_tag="MIV85_003741"
     CDS             754..1791
                     /locus_tag="MIV85_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBY2963035.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            2600..>3138
                     /locus_tag="MIV85_003742"
     CDS             2600..>3138
                     /locus_tag="MIV85_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2963036.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMIS"
BASE COUNT         1179 a          407 c          476 g         1076 t
ORIGIN      
        1 tttgtaagta tcataggtag taatggaact ggtaaatcta ctttattaaa tataatatct
       61 gggcttataa aagaatcttc tggtcaaatt actttagata gtactactat aacaaattta
      121 gctgagtata aaagaactca aatagtaagt agagtttttc aagacccaag ccttggaact
      181 tgtccttcta tgacggttag agaaaattta tctctagcac ttaataaagg gaaattattg
      241 aacttaaaaa aatgtcttcg tcataaaacg aatgacttgg aacacttact tgaaggaatt
      301 tctttggatt taaaaaaata tttagatatt aaagtacaat atctttcagg gggtcaaaga
      361 caatcactat cactaattat gtctagctta gcaagtccta aggtcttatt actagacgaa
      421 catacagcag cacttgaccc aaaaacatca aatgaagtaa tagagttaac agataaaatc
      481 gtaagagaga aaaatataac tacacttatg gttactcaca acttgaaaca cgctcttcaa
      541 tatggagata ggttgataat gcttcataag ggtgaagttg tattagatgt aaaagataaa
      601 gaaaaaaaag atttaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtataagaa
      661 attaaaatct tagttttaat cagaaatatt tataatctat catatgaata tatgaacaaa
      721 tataattatt aaattttaag ggaggaaaat aaaatgataa aaagtaaaaa aatattaagt
      781 ttaattatag caggagtact tggtgtatca atgcttactg gatgttctca aaatgatggc
      841 tccaatgctt caaatgaaaa taaagaaaca gatagcaaaa aacaaaaaaa tataggtatt
      901 actcaattag tggaacatcc atctctggat aaagcaaaga aaggattcat caaagcactt
      961 gaagataaag gctataaaga tggagataat ataaaaatag atttccaaaa tgcacaaaat
     1021 gatatgccta ctacacaaag tattgctagt aagtttgtat ccgacaaaaa agatttgata
     1081 tatgctatat ctactccatc tgcacaagca gcttataatg ctactaaaga tattccaata
     1141 ataatgactg ctgttacaga ccctgtagaa gctggacttg ttaaatctct tgaaaaacca
     1201 ggtggaaatg tttctggtac atctgattat ctttcaattg ataaaacatt agaattggtt
     1261 aaaacattga ctccaaaagc aaagaaaata ggggttatat acaatactag tgaagttaat
     1321 tcaaaaatcc aagttgattc tctacatgat tatgctaaga aaaataatta tgaagtagtt
     1381 gaaaaaggaa tcagctcttc aagtgaagtt aaccaagcta tttctagttt agttggtaaa
     1441 atagatgttt tatatgtccc tactgacaat ttaatagttt cttctatgcc aatagtttct
     1501 aaagttgcta atgaaaacaa gattcctata atagcctctg aagaaggttc tgtatcttct
     1561 ggtgctttag cttgttgtgg aatagattat gaaaaactag gttataaggc tggagaactt
     1621 gctattgaag tattagaagg aaaatctgtt ggcgatatac cagttactac attagatgaa
     1681 actgaaataa taattaacga agatacacta aaagcacttg acatgcaaaa gttatcagca
     1741 gataatataa agtatataaa gtcagatgaa aatgcaaaat ctacaaaata aaacttatta
     1801 atttcaaaaa ataggtaata tgaagtaggt aatatgaaaa ctttatataa taagtactct
     1861 tatccaccct aaccctttga aaattgtgct tattgtagca atttgaatat tgcatataaa
     1921 gttattcatt ttccataaaa gtcgtctata ttgacgactg attatgaaag ttatataact
     1981 ttctaatcac tacttgagct gtccaaaaga attttaatat tctccagaca gctttttttt
     2041 atgatatttg attgatatac atgtctagtt attccatatt tagtaaatat tttgataaaa
     2101 tttccacatt cacttataac ttaggataac gtttttttca aacaatacat taatttaaaa
     2161 gtattctgag tatacattat ttagtatttt aattaaattt agcagttgac ttttattatt
     2221 gtataattta taatttataa caagtcgaga atacatataa ttttctgact aattaaaata
     2281 ttaaaaggga gagataatta tgaatacttt attaaacaat agaaaatatt attattatta
     2341 tagccactat ttttagggtt tgtacctacg ttttaacata gatacagacc ccttaagact
     2401 actaaaattt tgggattgta tctatgttgg ctatattgtt tataaagttt tcatttaact
     2461 atataagagc cacatagatt aaactatgtg gcttattcgt gtttttacca catagttttg
     2521 tacactatgt ggttttttta tacacaaaat tagcaaataa ttaaaattat aaaaatattt
     2581 tcaaaggagt gttttattta tgtcaggtat tatatctgta atgacgcaaa gtttaatttt
     2641 atcgattatg gcactggggg tttatataac ttacaaaatc ttagattttc cagatatgtc
     2701 tgctgatggt agctacacaa tgggtgcttc tattgtagca ttttctctta ctaatggtat
     2761 ttctcctgta gtagcaactt taatggctat cttatgtggt tgtactgctg gtcttgttac
     2821 agggattctt cacattaagt ttaagatatc taacttactt tctggtattt tagttatggg
     2881 aatgctatac tctatcaatt taagaataat gggaaaatca aatattcctc tatttagctt
     2941 taaacactta ttcaatgggg aaatatctcc tatagtttta gccttagctt ttgtattcat
     3001 ctgtaaagtc cttttagatt tattcctaaa aacaggtctt ggatacactt taaaaggtgt
     3061 tggtgataac tctcaaatga ttaaatccct aggtataaat atcggttcta taaaaatact
     3121 aggacttatg atttcaaa
//
LOCUS       DAGQVA010000156         3112 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.162, whole genome shotgun sequence.
ACCESSION   DAGQVA010000156 DAGQVA010000000
VERSION     DAGQVA010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3112
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.162"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            34..1878
                     /locus_tag="MIV85_003743"
     CDS             34..1878
                     /locus_tag="MIV85_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBY2963037.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            2200..2784
                     /locus_tag="MIV85_003744"
     CDS             2200..2784
                     /locus_tag="MIV85_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBY2963038.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSLDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         1223 a          286 c          467 g         1136 t
ORIGIN      
        1 aaaattagaa caaatagata caaggagata aaaatgcaaa agagaatttt aagaaatttt
       61 atatttacgg gtaaaaatat tttaagtaaa cttgttttta taataaaata taattttagt
      121 acattaattt tatttgaatt atttcataaa ggattagcct tattttttat atggccatct
      181 attagatata tatttgatat tttaataaaa agtttacata tagtctacct aaatatggat
      241 aattttataa aagttttgac caatcccatg tcaatagttc tgataatact atcagttata
      301 atactagctt tttatgcatt ttttgaattt acctctgtaa ttatttgttt taataaatcg
      361 ataaaatatg aaaaaatagg gttatttgaa ctctttaaaa tatcatttga gaactctata
      421 aaattgttat atcctaaaaa tatactatta tttatatttg tgatattaat aattccatta
      481 gtaaatacag ttttaatttc agggtttata ggaaaaatac aaataccaga gtacatatta
      541 gattatataa agtctgatat aattttaaat ataatctata tgatttttct tttaataata
      601 tatatttcgg ttattagatg gatttttagc attcatgaga taactttaaa tacagaaaat
      661 tttaaaagag caagaaaaga aagtgttaat cttataaagg gaaagattat aagaacaatt
      721 atttattcat taatattatc tttagtagta gctattattg gatatgcgat ttatcatagt
      781 ggaattatat ttataggcat atggactaaa tattgtactg atatggaatt tttgaagaat
      841 gtatttataa atagatgtat tgcatttgaa gaatatttta gattgatttt atcaatattc
      901 atttttatat tggacattgg atttatctca gcaacttatt atcaatataa aggagtaaat
      961 atttctaaaa ataatattaa aaaagagaaa aaatctatat caaaaattgt ttttaattta
     1021 gtattaatat tattgatttc ttatatagag tcagttgcat tttcttcaca tataaatggt
     1081 atgtttaata cgtcattttc attttataca acagcaattg ctcatagagc aggagctgaa
     1141 atggctccag agaatacttt ggcagcaata gaagaagctt cacatgctaa agctgattat
     1201 gcagaaatag atgttcaaga aactaaagat ggagaactta ttgtacttca tgattcaaac
     1261 tttaagagaa ctacaggagt agataaaaat gtttgggatg taaattataa tgaagtaaag
     1321 acatatgatg cgggaagctt ttattattat ggaaaaggtt attatgatga aaagtttgtt
     1381 ggggaaaaga taccaacact caaagaaatg ataaaatatt ctaaaggtaa ggtgaaatta
     1441 ttaatagaaa taaaacttaa tggacatgaa aagggagacg tagtaaaaaa agttgttcag
     1501 ttaattaaag aaaataattt tgaaaatcaa tgtatagttg catctatgga taaaactata
     1561 ttacaaaaag taaaaaaact ggatgagaat ttactgacat gctattttat ggcaattgca
     1621 tatggtgatt tttcaaagtt aaattatgtt gatatatatg gaattgaatc aacttttgtt
     1681 aataaaacag tagtagaaaa gattcataaa atgaacaaaa aaatcttcgt ttggactgtt
     1741 aatagtgaca gtttaattga gaaaatgctt gacctaaatg tagatagtat tattacagat
     1801 aatccatacc ttatagagag tgcaatttat tggaagaaaa atggatttat tagtcaagtg
     1861 tcagattatt tattttaaat attctataat tgtattatcc agtaaaagag atattattaa
     1921 aatcaataat atctcttttt aacataaata aggttgttaa attaaggcta ttcttataaa
     1981 aattgtgttt atcagatata aataaggaat aaaagtaaaa aaattgctat gacattatta
     2041 caattaaaag agttttaata tgatagagag gtagattgtc aactgtatat ttaataaatt
     2101 ttattattta ttagatttta tataagtaaa atatatagat atataaatct tatgctagaa
     2161 tatatatgaa aaacaatata gatttggagg gttaaaagca tgacagagcg agaaaaaatg
     2221 ttggcaggag aactttacga ttgtggtgat attgagttgt taactcaatg gcataaagca
     2281 aaagacctag taagagatta taaccaaaca gattccttgg atttggaaaa aaaagaaaaa
     2341 atattaaatg agttacttgg tggtaagggt aaaaacttat ggattactgc accgtattat
     2401 gtagattatg gaaataatat ttattttgga aataattgtg aagtcaatat gaattgtacg
     2461 tttttagatg ataataaaat tatcattggg gataatgcac taatcgcacc aaacgtacaa
     2521 atatatactg catttcatcc aactaatgct ggtgatagat ttggtaatgc caaagaagat
     2581 ggttcatttg aattttgtaa aactcaaaca gctccagtta ctattggaga taatgtttgg
     2641 attggcgggg gtgctattat catgccaggt gttactattg gagataatgt agttataggt
     2701 gcaggaagta ttgttacaaa agatattcca agtaatatga ttgcatacgg aaatccatgc
     2761 cgtattattc gagaaaataa ataaagttaa attttcttgc aaaatctcaa aaaacacctt
     2821 tcttacttta tacatagggt attttctaat actttcacat ccatattcat ttgttaaatt
     2881 tttgtggaat gtagttttta tcacttctat cttacatttc caccattttt ttataaaagt
     2941 cattccttta tagatttatt tataatagta tatattctat ttgatgtttg aataagcact
     3001 tatttttaag taaaatacta acttctaggt tagtatttta ctatagtatg atgattaagt
     3061 aagaataaaa tactataata cataaagctt aataaatata atttttattt ta
//
LOCUS       DAGQVA010000157         3052 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.163, whole genome shotgun sequence.
ACCESSION   DAGQVA010000157 DAGQVA010000000
VERSION     DAGQVA010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.163"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..347)
                     /locus_tag="MIV85_003745"
     CDS             complement(<1..347)
                     /locus_tag="MIV85_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2963039.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSEL"
     gene            566..799
                     /locus_tag="MIV85_003746"
     CDS             566..799
                     /locus_tag="MIV85_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2963040.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            783..1196
                     /locus_tag="MIV85_003747"
     CDS             783..1196
                     /locus_tag="MIV85_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963041.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            1215..1511
                     /locus_tag="MIV85_003748"
     CDS             1215..1511
                     /locus_tag="MIV85_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963042.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITNEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            1794..2111
                     /locus_tag="MIV85_003749"
     CDS             1794..2111
                     /locus_tag="MIV85_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963043.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            2247..2711
                     /locus_tag="MIV85_003750"
     CDS             2247..2711
                     /locus_tag="MIV85_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963044.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR"
BASE COUNT         1101 a          395 c          401 g         1155 t
ORIGIN      
        1 agttcactta atttatcttc atccacttcg tcgtcttcac catgtaacgc tgacattaaa
       61 cttgaaattg aatttttatg tatgttcttc aaaaattcct ttgtttcaaa ccttagatat
      121 tttttctctt ttactagtat attataatgt gtaagtttgc ctattttctc tgtacttaaa
      181 aactcccttc gctctaatct tttcaaaact gtaaatgtag ttgattcatt ccactcatat
      241 ttttcttcca ttgcagcaac taattcccta gaagttaata ccttgttagc ttcacaaata
      301 tatctcataa cttttaattc cgcttctggt aatttactaa ttttcataat tcgcgcccct
      361 ttgccgattt atgtatatgt taaattctat atcaataaag ttttacaaac aagagaatta
      421 aggtaaataa ttccatccaa tttttaccat attattcttt taggttttat aatacttatc
      481 taatgagatt gacattttac tcattttagg atattatgaa gctaacttca catgaagtta
      541 gcttcatata gaaagaggtt atggaatgaa aacaaaagta cgagaatttc gaacaaatat
      601 gggtctaaca cagcaacaac tcgctgattt agtccatgta tcaaacagaa caattatttc
      661 tattgaaaaa gagcaatata gcccttctct tatgcttgcc tatcgtatgg cacaagtgtt
      721 tggtacaacg attgaagaac tatgttgttt aaaagaaaat aaagaaatgg aggataaaaa
      781 acatgaaagt aaagagtaaa cgaagtttta tagtgggtat tatagtttgt atgttatgtt
      841 gtgctagttt agttatttat tgcattttaa aagataaaag attcctaatt tcatcatttc
      901 ttttaattgt aatagcaatc tttaattttt gtaatgcttt ttcaagaaaa ggcattgttg
      961 aagaattaca cgatagtgca gatgaaagag acttgtactt aacaatgaaa acaagtcata
     1021 tcttagttaa aattatgaat tatacattat ttacttttac atttcttttc atcatagctt
     1081 atagtgcatg gaaaaatcaa tcacttctag ttatagctat aacactatgt gtcattgaga
     1141 tttttttatt tgttgcatat ttacttatca atatattttt agagaaaaaa gagtaaatac
     1201 aaggggtgat ataaatgtat tttaaaactt atatactaaa aagagaagta aataacaaac
     1261 aactagagat aactcgaagt tttgacttag ataatctaat ttgtactgca acagagattt
     1321 tgaaagataa tgagattgat ttgataatta ctaatgaagt aaataatgtt gtttggagaa
     1381 atgaaaaaag cactccccca gcaagagaat gcttagttat agctatagaa gtgtattggt
     1441 ggtacacttc tattttttta ttatatcata taaattatgt tatcaaaaag agctatttaa
     1501 atcgatttta aggtgtgttg aataaggttc ttgatagttt atatattgat gaatttcaaa
     1561 aaaataagca ctctttattg taaggagtgc tttggtgtat gttaatcttc tatctaatac
     1621 aattataaca tgtcttatgt tttagtatga taattttcgt tcgctttatt attacaattt
     1681 ttactatagt tttatctatc ctgttaatat ttgtaatatt ttagatgctc tttgtacttg
     1741 tgttactgat atactttgat taagaaaagc aaatttaata ggaggtatct gctatggatt
     1801 ttggaaatat caatcttata cttattggaa taatagttat aataggaact acaataatat
     1861 atttaattaa acctaaaact gctttttgta gtaaaaaata ttttaataaa ttagaatcaa
     1921 tatatggaaa tatagataag aaaaaaactg ttaaactaga agtactttat cgctatgtaa
     1981 caggtcttga gtatatagca ataggcttat ttacaagaag attagatatt acaataatag
     2041 caataatatt agtagccatt ataacaacag cattatatta tctaattaga aagaaatata
     2101 taactatata aaaaataata tcttataaat aataagccta tcattatact ctatttttag
     2161 ctaaaatcgt tcgacaaatt gctgatataa gttcttaaat atgctataaa ttaaagtata
     2221 ttatataaca ttgtaggagg gattttatgg attttgggga agttaaatca gagttaagtg
     2281 acaaagacct taaagataat gaagaagctt taaacaagta taaaaaatat tatttaaaag
     2341 tttataagta ttatagtgaa atggattcca taaaaagtat tcaagatata gaaatagagc
     2401 aatctaggct taaaggacag ttacaaaaaa atagtaaccc catttttgct ttgtatatat
     2461 ctattatggc tgttgtattt tctacaacaa ttaacttaac atttgattta tcagatatca
     2521 ctaattattt tattagaatg attatgacac ttttatttat tgtacttctt atttttttag
     2581 ttaacaaggg cattcttcca atagctatac cttatagaaa taatatacaa ttttatacta
     2641 ctgcattaga tgtattagaa gatatgaaaa agaaaatact tagagagaga aagtataaaa
     2701 aaagaaggta acaaccaact ctagttgcta ccttctaatc tatttaacta agttttctac
     2761 ttcactaaat gctttctcat ttccatttcc accaatttga gttatatttc taaattctct
     2821 tttatttatt aaactttttt gagtatcact tattccattt ccaactaata gtactagaga
     2881 ttctgtctta cctgcaagta ctcctactga taaagcgtca actaaatcat cttctctatt
     2941 ttctccattt ttgggttaat ataattctct atctccatta taccatttta taccaaacaa
     3001 agcacttgaa acagtagaat atccaagtgc tttatatgtc tatttattat tt
//
LOCUS       DAGQVA010000158         2942 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.164, whole genome shotgun sequence.
ACCESSION   DAGQVA010000158 DAGQVA010000000
VERSION     DAGQVA010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2942
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.164"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..1418
                     /locus_tag="MIV85_003751"
     CDS             <1..1418
                     /locus_tag="MIV85_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBY2963045.1"
                     /translation="LELEKQYKLAINSIEKDILAWYNRFAKNEGISLLEAKKLLNTRE
                     LEEFKWSVEEYIKYGKENAINQKWMKELENASARVHITRLEALKLQIQQQVEVLYGNE
                     LDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWSLMSLDTNRINKIISKPWAIDGLNFSE
                     RIWGKYRPTLVNELHTKLTQSIIRGENPKNLVNDFAKRFNVSKSQAKNLIMTESAFFA
                     SASRKDCFSDLEVEKYEIIATLDLRTSNICRELDGKIFDMKDYQVGITAPPFHCRCRT
                     TTAPWFEDEEGYRAARGEDGKTYYVPSSMKYNEWYEKYVKNNSKQTGAKYTKGDIEWN
                     IRREEEAELYYDNIRNRKDDISKISKNTNWSEKSIGQIKNHIFYNTHIMRDGTRRMLD
                     SDYSMSVAWQRLINGTYEDIDILLLKHEYLESIFEKKYNISNLEAHRMTEKKHDWYKE
                     LIKQKGEFEEDDCLNELIRKE"
     gene            1384..1626
                     /locus_tag="MIV85_003752"
     CDS             1384..1626
                     /locus_tag="MIV85_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963046.1"
                     /translation="MIVLMNLLEKNNEYVIYSYGYEENKLDGRIKIYLDDFYNYEIIK
                     ESKDEHISKSATLKAISKLIKAAKNNDLKKEMSYQC"
     gene            1697..1891
                     /locus_tag="MIV85_003753"
     CDS             1697..1891
                     /locus_tag="MIV85_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963047.1"
                     /translation="MYILTQVIAVVCVVQIFINCIANVNVGILCNKLKEKNEANIDKV
                     SDEILKRVGEELNESLDKSL"
     gene            1936..2499
                     /locus_tag="MIV85_003754"
     CDS             1936..2499
                     /locus_tag="MIV85_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBY2963048.1"
                     /translation="MDWLKELLEGIKIENNKIDVVSLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            2511..>2942
                     /locus_tag="MIV85_003755"
     CDS             2511..>2942
                     /locus_tag="MIV85_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBY2963049.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTT"
BASE COUNT         1276 a          302 c          527 g          837 t
ORIGIN      
        1 atcttgaatt agaaaagcaa tataaactag ctataaatag tatagaaaaa gatatattag
       61 catggtacaa cagatttgcc aaaaatgaag gaatatcttt attagaagct aagaaactac
      121 taaatacaag agaactagaa gagtttaaat ggagtgttga agaatatatt aaatatggta
      181 aagaaaatgc tataaatcaa aagtggatga aagagttaga aaatgctagt gcaagagttc
      241 atataacaag gcttgaagct ttaaagttac aaatacagca acaagtagaa gttttatatg
      301 gaaatgaact tgatggtatt gataaactaa tgagagatat ttatacaagt ggatactatc
      361 atacagcttt taatgttcaa caaggagtaa acgttggttg gagtttaatg agtcttgata
      421 ctaatagaat aaataaaatt atctctaaac catgggcaat agatggatta aactttagtg
      481 aaagaatttg gggtaagtat agacctactt tagtaaatga actacatact aagctaactc
      541 aatcaattat tagaggtgaa aatccaaaaa atttagtaaa tgactttgct aagagattta
      601 atgtatctaa atcacaagct aagaatttga taatgactga atcagctttc tttgcatcag
      661 caagtagaaa agattgtttt agtgatttag aagtagagaa atatgagatt attgctacat
      721 tagatttaag aacttcaaat atatgcagag agttagatgg aaaaatattt gatatgaaag
      781 attatcaagt tggaataaca gctccaccat ttcattgtcg ttgtaggaca acaacagctc
      841 cttggttcga ggatgaagaa ggctatagag cagcaagagg agaagatgga aaaacatatt
      901 atgtaccatc tagtatgaag tataatgagt ggtatgagaa gtatgttaaa aataatagta
      961 aacaaactgg tgcaaaatat actaaaggtg atatcgagtg gaatataaga agagaagaag
     1021 aagcagaact atattacgat aatattagaa atagaaaaga tgatatttcc aaaatatcaa
     1081 agaatacaaa ttggtcagaa aaaagtatag gtcaaattaa aaatcatatt ttctacaata
     1141 ctcatataat gagagatgga actagacgta tgttggattc tgactatagt atgtcagttg
     1201 cttggcaaag acttataaat ggtacatacg aagatattga tattctctta ttaaaacatg
     1261 aataccttga aagtatattt gagaaaaagt ataatataag taacttagaa gcccatagaa
     1321 tgactgagaa aaagcatgat tggtataaag aattaattaa acagaaagga gagtttgaag
     1381 aagatgattg tcttaatgaa cttattagaa aagaataatg aatatgttat atatagttat
     1441 ggatatgaag aaaataagct tgatggaaga ataaaaatat atttagatga tttttataat
     1501 tatgaaataa taaaagagtc aaaagatgaa catataagta aatcagcaac gttaaaagct
     1561 atttctaaac ttataaaagc tgctaaaaat aacgatttga aaaaagaaat gagttatcaa
     1621 tgttagaagc acttactgaa caataaatta gtaggtgctt ttattatgta aaagtttaaa
     1681 aaagtaggtg attttaatgt atatattaac tcaagttata gctgtagttt gtgtagtaca
     1741 aatctttatt aattgtattg ctaatgtcaa tgtaggtatt ctttgcaata aattaaaaga
     1801 aaaaaatgaa gctaatatag ataaagtttc tgatgaaatt ctaaagagag taggagaaga
     1861 attaaatgaa tcactagaca aaagtcttta aagacttttt ttattgtgta aaaaatgaaa
     1921 ggagatattt aaaagatgga ttggttaaaa gaattgctag aaggaataaa aatagaaaat
     1981 aacaaaattg atgtagtttc tcttcaaaaa tctatagaaa agaaaataaa agagactaca
     2041 attactcaag aagattatac aaatcttgaa acacagctta atacagctaa tgaaactatt
     2101 aaaaagtttg aaggaggtat gacaaaagaa gatgtagaga atctaaaaac aacttatgaa
     2161 actgataaga aaactttgga agaaacttac aaaaaagaaa ttgaagaaaa agattttaat
     2221 tactggttag gtgatgcttt taaatctgtt aaatgtagag atgaaatagc attaaaagct
     2281 catttagata tagaagcact aagaaatagt aaagacagac aaaaagcttt tgaagagcaa
     2341 ataaatcctt tgaaacagga taaagattat ttgtttaatg caacactaga aggtgaagaa
     2401 cctaaaatag atactataac accagggcaa gagcctaaga taaatgattt tggttttaat
     2461 tttactgggg taagacctca tgaaaataat aataaatagg aggaaataaa atggcagcac
     2521 taaattatgc aaaagaatat tcaaatgttt tagcacaagc atatccttat actttaaact
     2581 tcggggattt gtatgcaaca ccaaataatg gaagatatag atggactggt tctaaaacaa
     2641 tagaaatacc aactatatct acaactggaa gagtagattc aaacagagat acaatagcag
     2701 tagctcaaag aaactatgat aatgcttggg aacctaaggt attaactaat caaaggaaat
     2761 ggtctacatt ggttcatcca gcagatataa accaaactaa ttatgtggct tcaataggca
     2821 atataacaaa agtatataat gaggaacaaa agtttccaga gatggatgct tactgtatat
     2881 ctaaaatata tgctgattgg accgcattag gtaacacagc agatacaact gttcttacaa
     2941 ca
//
LOCUS       DAGQVA010000159         2751 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.165, whole genome shotgun sequence.
ACCESSION   DAGQVA010000159 DAGQVA010000000
VERSION     DAGQVA010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.165"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     regulatory      249..346
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            401..577
                     /locus_tag="MIV85_003756"
     CDS             401..577
                     /locus_tag="MIV85_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963050.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            803..1003
                     /locus_tag="MIV85_003757"
     CDS             803..1003
                     /locus_tag="MIV85_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBY2963051.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(1167..1379)
                     /locus_tag="MIV85_003758"
     CDS             complement(1167..1379)
                     /locus_tag="MIV85_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963052.1"
                     /translation="MVCKIFITLKTILPKTQIIVTTHSPHILQIDSKEEMIVLDMAES
                     DNVYKKELKLGEYGVLGWTNEGLYLH"
     gene            1754..1936
                     /locus_tag="MIV85_003759"
     CDS             1754..1936
                     /locus_tag="MIV85_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBY2963053.1"
                     /translation="MFKFYNNATLMFLPGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            2007..>2751
                     /locus_tag="MIV85_003760"
     CDS             2007..>2751
                     /locus_tag="MIV85_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963054.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKR"
BASE COUNT         1063 a          306 c          376 g         1006 t
ORIGIN      
        1 tctggtaatt ttttatttag cataatatat tccttctttc aatttatgtc acttcttcaa
       61 atttatctag cttaaattat aataggagct ttttagaaca aaaactatat ttaattttta
      121 ccaggtactc tacgtgttta gtctgttttt aagtgtaaaa taatgttcat atctataaat
      181 ttatttaact ttcaaacaat cctgttgaat aataactaat tctattgtat tattttagtt
      241 gtagaataaa actaaatcgg caaaactaga gaaatttagt gacgcaaagc tatagggact
      301 aagacttata taaatatctt atgagttatg tcagccagtt gccaaagaga tagtgttctt
      361 tttgttttta tgaaagtttt ttagggggat aataatttat atgtttggaa ataaaatgga
      421 taaatgtaca catgtattga ctgcttatat tagcagttcg tatgattatt gtaatttttt
      481 agatacacag ttagatgatt ttatattaga gtacggagaa aatgtagtag agtcttgttt
      541 acaccaagta atggtattgg taagtaagta taattagata gacattgatt tctagaaaac
      601 cctttttagt tttatctaca tttatattaa tatatagcaa tgtaaaacgt ttaaatatat
      661 ttttaatatt aagaataatt aaaatgttaa ctaaaaaata taattaagta gacatttcta
      721 ttaatctatg atacaatagt atttgtggta atacacaatt aaatcaagta tatcttgata
      781 taggttaata ggagtatttt taatgaataa tggaatagtg aaatggttta ataatgaaaa
      841 aggattcggt tttatatcaa tggaaggtag agatgatgtg tttgctcatt tctcagctat
      901 acaaacttca ggatttaaat cattagaaga aggtcaacaa gtaagctttg atatagttaa
      961 aggtgctaga ggtcctcaag cagaaaatat aactatatta taatatatag atttttcggg
     1021 aaagactctt tttagagtct ttttttattg ttaatatatg taagataatc attggtgaag
     1081 taaataaggt atattgagta atgttcttga tagtttatat gctaatgaat ttcaaaaaaa
     1141 taagcactcc tataaaaaga gtgctcttaa tgtaaatata aaccttcatt ggtccagcct
     1201 aataccccgt attctccaag ttttaactct tttttatata cattatcact ttcagccata
     1261 tctaacacaa tcatttcttc tttagaatca atttgtaaaa tatgaggact gtgtgttgtg
     1321 acaattattt gtgtttttgg gagaattgtt tttaatgtaa taaaaatttt acataccaca
     1381 tagttgatat aaaacttaag actagcagac tcataagcaa ttagttgcct ctctttacat
     1441 accacatagt tgatataaaa cctagaggct ctcagagaag ttataagatg tttagtaact
     1501 ttacatacca catagttgat ataaaactcc aaaataaact tagcatctcc aatgtttaca
     1561 catatacaat gctcttaaaa ttgcagtgaa cgcgcaatat tgcaattgat aatacttatc
     1621 atatattctc aataccttat atttcaactg ctaaacctca atttatcaca aatatcgctc
     1681 actgcaaaat ttctatattt ttattatatc atagcatata attaatattt tcaattaatt
     1741 tttacattta attatgttta aattctataa taatgcaact ttaatgtttc ttcctggaac
     1801 taatataaaa actatttcag aaagattagg tcatgcagat ataaaaataa ctatgaatag
     1861 ctactctcag tttttagaag agatggacag agaagcattt gaaaatttga gcaaaatact
     1921 atttattgta ttttaaagaa gatgacttat tcaatatttg atgctagaat ataattaata
     1981 aaaatttaat tataggtgat tgtattatga atattattaa aagcataact ttactcttaa
     2041 cattattaat tgtgatatta atgacaggct gttccccaag agaaagtgct agtgaagttg
     2101 caaaaaaata tattgataag atgaactctg gtgactatga aacagcatat agtttattaa
     2161 gtaaagatag taaaaaaaaa attagtatag aaaatcttga agaatttcaa aatattttag
     2221 ttagtacaaa aagaataatt agttataaaa taggtaaaga aaaaatcata aaaaaatata
     2281 aacatgatgg aaaagaatat aaaaatgttg ttaaattaga agaaactttt aatataaaaa
     2341 accttcttta taaaaaagat gattctctaa aagtaaatag atattttgta gttgaaaata
     2401 acaaatacaa gctattattg tatgaaagtt tcaaaaaaga atttggtatt aatagtatgg
     2461 accttgctca acttaagctt aatgattttg gactaaaata ctttaaagaa gttgacctta
     2521 tactaaaaaa agctattgct attaatccta ctgattcaaa gctttattat gcccaagcat
     2581 gtaattatat gaattttgat ggatttcctg gttattcaga tacaacatat aatgctttag
     2641 attcaattaa taaatcttta aagtatttag ataaaaatga ttctgactac aaaaaaaatg
     2701 caagtaatat atataactta aaaggagtta ttcttatgtt tcacaaaaga t
//
LOCUS       DAGQVA010000160         2677 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.166, whole genome shotgun sequence.
ACCESSION   DAGQVA010000160 DAGQVA010000000
VERSION     DAGQVA010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.166"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(74..442)
                     /locus_tag="MIV85_003761"
     CDS             complement(74..442)
                     /locus_tag="MIV85_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBY2963055.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(625..1284)
                     /gene="deoC"
                     /locus_tag="MIV85_003762"
     CDS             complement(625..1284)
                     /gene="deoC"
                     /locus_tag="MIV85_003762"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBY2963056.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(1320..2507)
                     /gene="murJ"
                     /locus_tag="MIV85_003763"
     CDS             complement(1320..2507)
                     /gene="murJ"
                     /locus_tag="MIV85_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBY2963057.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLH
                     LKK"
BASE COUNT          864 a          477 c          288 g         1048 t
ORIGIN      
        1 acatattatt aaaaatattt tgcttcttaa aactgtgaga taaattttct atcttaatag
       61 aactactcat atattaatcc tccttgaaat taattataat atcaaccaat tcttctctat
      121 ttatttctaa tttgttagct tcttgaagta ggttttttac aaaattatgt ttaaaatttt
      181 cttttctagc ttcttttata atagtttttg caccatctga tacaaacatc cctatccccc
      241 tcttcttata taaaatattt ttatcaacca atatatttat accttttaat actgtagctg
      301 gattaatttt ataaagcttt gaaagctctg ttgttgatgg aacctgttct tcttctttta
      361 ttccatttga tagtatctca tcttcaattg ctcgtgctat ctgaataaat ataggttctt
      421 cattatttaa tactaatttc ataggttcct cctttctcca ttagttagtt actcaactaa
      481 ttaactatat aacttataat atcttgaaaa atattttctg tcaatactaa ataaaaaaca
      541 gagggaaaat tccctctgtt ttttgttctt tatatttata attaaatttt gatttttgta
      601 atcctatccc ataagttaaa aactttaata atctgttgta tcttcatttt ttaatatttt
      661 acatattgag ctagttccta acctttctgc tcctgcctct ataaattttt ctgcatcaga
      721 aattgattta actccccctg cagcttttat ttttacattt tttccaacat gctctttcat
      781 aagctttata tcttctaaag tagctccacc tgttcccatt ccagtagatg tttttataaa
      841 atctgaacct gacattgtta ctatttcaca catttttatt ttttcatctt catctaaata
      901 acatgtctct ataatgactt ttaatacttt atctcctata gcttttttta tttcttttat
      961 ttcttttcct atattatcat aatctttatt ttttatatct gaaatgttta caaccatatc
     1021 aacttcatct gctccatttt caatagcatc ttttgcttca aatacttttg tagcagtagt
     1081 ttgatatccc aaagggaacc ctatcactgt acatatcttt attttacctt ttagatattc
     1141 tgatgctctt ttcacatatg atggtggtat gcaaactgat gctacactca tatctacagc
     1201 ttcatcacat aaaattttaa tatcttccca tgtagttgta gcttttaaaa tagtatggtc
     1261 tactgttttt aatatatgtt tcataaaatc ctcctaaatt tataattaat ataattagat
     1321 tactttttta aatgcaattt tctctttgca atattcagta tcatatcaac ctcttcaact
     1381 ttaaaaatag tcattagtag tgtataaatt ccacctccaa ctataactga aatagctagt
     1441 gagacaaact cattaaatgt tcctactccc aaaattccaa atataaattt atacgtaaag
     1501 tatgataaaa cacccataat taaagatgca actaccgatt tcaaagttgc ttttattatt
     1561 ttatcttgtc caaaatatcc aacttttctc tttaggttca agaagagtaa caatatacat
     1621 gcaattgatg atgaactagt tgcaagagca agaccaccat gagccattgg ttttattaaa
     1681 actaagtcca atactatatt tacccctaca gatataatcc catttaccat aggtgttttt
     1741 gtgtcttgta atgaataaaa aacctttccc aaaatatctc ttaagccaaa tgcagtcata
     1801 ccaactgcat aaaaaattaa ggcagttgct gtcatttggg ttgccctcgc atcaaaagca
     1861 cctctctcaa aaatgattct aacaacagga gttgcaaaaa aaatagaagc aactgaaata
     1921 ggaatcatag aaattattat catatttata ctagatttaa ctgaactagt aaacttcttt
     1981 tgattatttt ctgcacttaa cttagataac ataggataca taacagatac tattgaagct
     2041 gtaaatgtcc ctgtaacaaa accatttaat ctatctgcat aagtaagtgc tggaatgctt
     2101 cctttaacta atgttgaggc taaagttgta tctaccaatg agttcacttg attaacagca
     2161 acacctataa atactggtga aagtaatgct agtaatttaa taaggctatc atctttaaag
     2221 tttaagtagt ataagtattt gtagttcgtt tttttaacaa aaaacatgta aaagagcagt
     2281 tgaactacca tagcaaccac agcaccaatt ggaagtatgt atggtccaaa tatggtactt
     2341 aacattattg aaataattat tactatatta tagggtatac ttccaaatcc aactacaata
     2401 aagttctctt taatttgtaa aaatgctgac ataacacttg taatacctat gaatattatt
     2461 cctgttctga acctcccatg actaaagtca cagggttcct gcttcataga attttgcata
     2521 ctaaaatatg tcttactaat tctccacagg ctatccccgt agttcctacg gttcttacat
     2581 acgttattta ttttgaattg ttattagtct taatccttct tttaatatat ttctacttgc
     2641 atttatatct ctatcgtgag tttcattaca actagga
//
LOCUS       DAGQVA010000161         2587 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.167, whole genome shotgun sequence.
ACCESSION   DAGQVA010000161 DAGQVA010000000
VERSION     DAGQVA010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.167"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..344
                     /locus_tag="MIV85_003764"
     CDS             <1..344
                     /locus_tag="MIV85_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBY2963058.1"
                     /translation="LDLKCSKTEKKFKKAIRELLWFVCEYLKISGSKSYDYKTVQITF
                     NHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDELERLKKQEDTQKEYDDLI
                     PNNQDGVIDET"
     gene            334..1731
                     /locus_tag="MIV85_003765"
     CDS             334..1731
                     /locus_tag="MIV85_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBY2963059.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIRHGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRHIYTSGYYHAAFNVQQGVNVGWS
                     LMNLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKNLV
                     NDFSKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGVTAPPFHCRCRTTTAPWFEDEEGYRAAKGEDGKTYYVPSSMKYN
                     EWYEKYVKHNSILEIKNSAIIDSIKEDIKNGKYNLNIHDGKQGKHLKEHNNYIEGRSY
                     LTITKEEAQELVNKHAGNGIIKFNRSGEWDKKELIEVDKNIGVNVNNITGEKTLTNKF
                     KIHYSKTGTHIVPAL"
     gene            1746..1946
                     /locus_tag="MIV85_003766"
     CDS             1746..1946
                     /locus_tag="MIV85_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963060.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            2012..2575
                     /locus_tag="MIV85_003767"
     CDS             2012..2575
                     /locus_tag="MIV85_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBY2963061.1"
                     /translation="MDWLKELLEGIKIEDNKIDVASLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
BASE COUNT         1124 a          256 c          495 g          712 t
ORIGIN      
        1 tactggacct taaatgttct aagactgaaa agaagtttaa aaaagcaatt agagagcttt
       61 tatggtttgt gtgtgagtat ttaaagataa gtggtagtaa gagctatgat tataaaacag
      121 ttcaaattac ttttaatcac tctatgataa taaatgaagc tgaaaagata gatatggcag
      181 ctaaatcaac tggaattgta tcagatgaaa ctattgtttc taaccatcct tgggtcgagg
      241 atgtaaatga cgaacttgag agacttaaaa aacaggaaga tactcaaaaa gagtatgatg
      301 atttaattcc taataatcaa gatggtgtta tagatgaaac ataaagatta ttggaggaag
      361 agatttgaac aattagaaga agctcaaaat aacaaaagtg taaaatatta tcttgaatta
      421 gaaaagcaat ataaactagc tatgaatagt atagaaaaag atatattagc atggtacaac
      481 agatttgcca aaaatgaagg aatatcttta ttagaagcta agaaactact aaatacaaga
      541 gaactagaag agtttaaatg gagtgtcgaa gaatatatta gacatggtaa agaaaatgct
      601 ataaatcaaa agtggatgaa agagttagaa aatgctagtg caagagttca tataacaaga
      661 cttgaagctt taaagttaca aatacagcaa caagtggaag tgctttatgg aaatgaactt
      721 gatggtattg ataaattaat gagacatatt tatacaagtg gatattatca tgcagctttt
      781 aatgttcaac aaggagtaaa cgttggttgg agtttaatga atcttgatac taatagaata
      841 aataaagtta tctctaaacc atggactagt gatggattaa attttagtga aaggatttgg
      901 ggcaaacata gacctgcttt aattaatgag ttacatacta agctaactca atcaattatt
      961 agaggtgaaa atccaaagaa cctagtaaat gacttttcta agagatttaa tgtatctaaa
     1021 tcacaagcta agaatttgat aatgactgaa tcagctttct ttgcatcagc ttcaagaaaa
     1081 gattgtttca atgatttaga tgtagagaag tatgagatta ttgccacact agacttaaaa
     1141 acatcaaata tatgtagaga gttagatgga aaagtatttg atatgaagga ttatcaagtt
     1201 ggagttacag ctccaccatt tcattgtcgt tgtaggacaa caacagctcc ttggtttgag
     1261 gatgaagaag gttacagagc agcaaaagga gaagatggaa aaacatatta tgtaccatct
     1321 agtatgaagt ataatgagtg gtatgagaag tatgttaaac ataatagtat cttagaaata
     1381 aaaaatagtg ctataataga tagcataaaa gaagatatta aaaatggtaa atataattta
     1441 aatattcatg atgggaaaca aggaaaacat ttaaaagagc ataataatta tatagaagga
     1501 agaagctatt taactataac aaaagaagaa gctcaagaac ttgtgaataa gcatgctggc
     1561 aatggaatca taaaatttaa tcgaagtgga gaatgggata aaaaagaact tatagaagtt
     1621 gataagaata taggggtcaa tgttaataat attacgggtg aaaaaactct tacaaataag
     1681 tttaagatac attattccaa aactggaaca catatagtac cagctttata aggaggaaaa
     1741 ataaaatgaa attatgggaa tatgtaggga aaaatgttca aataacttgt gtagataagc
     1801 aaataataag aggaaagtgt gatggatata cacaagcttt agataatgaa ccagaaatag
     1861 caagtatatc aatagctagg gatggttatg gaattgaagt ttatgaaaat gaaatagaat
     1921 ctatcgaaaa tataaataag gaatgactaa gcatgtactt aaaaataagt agatgctttt
     1981 attttgtaaa aaatgaaagg agaaatttaa aatggattgg ttaaaagaat tgctagaagg
     2041 aataaaaata gaggataaca agattgatgt agcttcttta caaaagtcta tagaaaagaa
     2101 aataaaagag actacaatta ctcaagaaga ttatacaaat cttgaaacac agcttaatac
     2161 agctaatgaa actattaaaa agtttgaagg aggtatgaca aaagaagatg tagagaatct
     2221 aaaaacaact tatgaaactg ataagaaaac tttggaagaa acctacaaaa aagaaattga
     2281 agaaaaggac tttaattact ggttaaatga tgcttttaag tctattaaat gtagggatga
     2341 aatagcgtta aaagctcatt tagatataga agcactaaga aatagtaaag atagacaaaa
     2401 agcttttgaa gagcaaataa accctttgaa acaggataaa gattatttgt ttaatgcaac
     2461 actagaaggt gaagagccta aaatagatac tataacacca gggcaagagc ctaagataaa
     2521 tgattttggt tttaatttta ctggggtaag acctcatgaa aataataata aataggagga
     2581 aataaaa
//
LOCUS       DAGQVA010000162         2560 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.168, whole genome shotgun sequence.
ACCESSION   DAGQVA010000162 DAGQVA010000000
VERSION     DAGQVA010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.168"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            636..2432
                     /locus_tag="MIV85_003768"
     CDS             636..2432
                     /locus_tag="MIV85_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBY2963062.1"
                     /translation="MKPTMEILTKLQENSKKNHDEVFTRLYRYLLRPDIYYVAYQHLY
                     SNKGAGTKGVTDDTADGFSEIYIENIIEALKNEMYQPKPVRRTYIKKSNGKMRPLGLP
                     VFTDKLIQEAIRMILEAIYEPIFSDYSHGFRPARSCHTALAQIKKEFTGARWFIEGDI
                     KGCFDNINHAVLVEIINQKIKDARFLKLIRSFLKAGYMEDWKYHKTYSGCPQGGIISP
                     ILANIYLNELDRHVMKIKKEFDVATKARYTPEYTKLVGLRQRLHNKIKNSNGIEREKL
                     IEEYKSATAQMLKLPAKQCDDKKIKYVRYADDFLIAVNGNRQDCEKIKQELTEFISTT
                     LKMELSQEKTLITHSNTPARFLGYDVRVRRDQQIKPKGKFKTRSMNNKVELSIPFKDK
                     IEKFLFSNGIVKQRSDNGKLEPIHRPQLLNRTDLEIVTIYNAELRGICNYYGLASNFN
                     KLIYFNYLMEYSCLKTLAGKHRSKVSKIRAMYKDGTGKWAIPYETKTVIKKMYFANYA
                     DCKGKKFTDIVPQTAKNYSHDVTTLESRLKAKICEVCGCTESDRYEIHHVNKVKNLKG
                     KSEWEKIMIAKRRKTIVVCHKCHMAIHHGEKK"
BASE COUNT          977 a          439 c          533 g          611 t
ORIGIN      
        1 ttagaagtag attaaagaaa gggggacaga aaaaaaaggc actaccccgt aagataacac
       61 gggaaaccac ctgcctaacc gaaaggtgaa aactgtacgg gaaaatagca cggcaggaaa
      121 gcagaaagtt gttcaaagac aatagagcac gactgaactg caaggttaag tgaatatgag
      181 gataaaacta gatttgttga atgtgagttc caaacctctg ttacgtgtgg acacaggaaa
      241 cttgtctgaa acctgtggta tgagtaacgc tgaaaataaa tgcctttcag tgggttatca
      301 attaactcat acggtacgct ggagaaccag tagtaacgga acgaaagcat atccgacaat
      361 tcacaccagc ctactacttt cgtcaactgg agattaccta aaccagaatg cctacaatgg
      421 ctatgtgtaa tgctcttgta gtgataaatc acaaggctat gctaagtgag atgacgctga
      481 aaatctggca aggtaacgga gctttcatag tagtctgaga accctgaaaa gacagggaaa
      541 gccgtaaaat cggatacggg aaaaccgttc acatggcgaa ggaaagcagt cttagcgaat
      601 taaaattaga aattgattag ggaggaaaac ctcaaatgaa accaacaatg gagattttaa
      661 ccaaattaca ggaaaattca aaaaagaacc atgatgaagt atttacaagg ctctatcgat
      721 atttactccg tccagatata tactatgttg catatcaaca cctctactcc aacaaaggag
      781 caggaacaaa gggtgtaaca gacgacacag cggacggttt tagcgaaata tatattgaaa
      841 atatcattga agccttaaaa aatgaaatgt atcaaccaaa accagtaaga cgtacataca
      901 tcaaaaaatc aaatggcaaa atgcgtccct taggactgcc tgtctttact gataagctga
      961 tacaggaagc aatacgcatg atattagaag caatctatga gcctattttt tcagactact
     1021 ctcacggttt ccgaccagca agaagttgtc atactgctct tgctcaaata aaaaaagaat
     1081 ttacaggagc acgctggttt atagagggcg acataaaagg gtgctttgat aacatcaatc
     1141 atgcggtact tgtggaaatt atcaatcaga aaattaaaga tgcacgtttt ctgaaactca
     1201 ttcgttcatt cttaaaggca ggttatatgg aagattggaa ataccacaaa acatatagcg
     1261 gttgccctca aggtggcatc atttcgccta ttcttgcgaa tatctacctt aatgaattag
     1321 accgtcacgt aatgaagata aagaaagagt ttgatgtggc aacaaaggca cgttatacac
     1381 cagaatatac aaaactggta ggactacgcc aaagattaca caacaaaatt aaaaatagca
     1441 acggtataga aagagaaaag ctgattgaag aatataaatc tgcaacggct caaatgctta
     1501 aactaccagc gaagcaatgt gacgacaaga aaataaaata tgtgcgttac gctgatgatt
     1561 tcctaatagc tgtgaatggc aatcgacagg attgtgagaa gattaagcaa gaacttacag
     1621 aatttataag taccacatta aaaatggaac ttagtcaaga aaaaactctg attacacaca
     1681 gtaatactcc tgctcgtttt ctcggatatg atgtcagagt acgccgtgac cagcagatta
     1741 aaccaaaagg aaaattcaaa acccgttcta tgaataacaa ggtggaattg agtattccat
     1801 tcaaagacaa gatagagaaa tttttatttt caaatggaat tgtaaagcag aggtcagaca
     1861 atgggaaatt agaacctata caccgaccac aactgcttaa taggacagat ttggaaatag
     1921 tgactattta taatgcagaa ttaagaggta tctgtaatta ttatgggttg gcaagcaatt
     1981 ttaacaagct aatctatttc aattatctta tggaatatag ctgtttgaaa acacttgcag
     2041 gaaagcaccg ttccaaagtt tctaaaatta gagctatgta taaagacggt acaggcaaat
     2101 gggctattcc ttatgaaact aaaacagtaa taaagaaaat gtattttgcg aattatgctg
     2161 actgcaaagg aaagaagttt actgatattg ttccacaaac agctaaaaat tattcccatg
     2221 acgtaacaac attagaaagc cgattaaagg cgaagatatg tgaagtatgt gggtgtacgg
     2281 aaagtgacag atacgaaatt catcatgtaa acaaggttaa aaaccttaaa ggaaaatcag
     2341 aatgggaaaa gataatgata gccaaaagac ggaaaacaat cgtggtatgc cacaagtgtc
     2401 acatggctat acatcatggc gaaaagaaat aacctgtaac ggagcaaaga tggagagccg
     2461 tgtgcattga gaaatgcaag cacggttcgg ggagaggact gcacaaacct accctagaaa
     2521 taaggaaagg cggtgctttc ctactctact atgtgggaaa
//
LOCUS       DAGQVA010000163         2549 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.169, whole genome shotgun sequence.
ACCESSION   DAGQVA010000163 DAGQVA010000000
VERSION     DAGQVA010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2549
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.169"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..464)
                     /locus_tag="MIV85_003769"
     CDS             complement(<1..464)
                     /locus_tag="MIV85_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2963063.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVIICPEKQFKTKNEEKSYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICDKLGTVFKNRGAKLDKRLYILNSSKPTAVLIESFFCDNKEDY"
     gene            complement(464..895)
                     /locus_tag="MIV85_003770"
     CDS             complement(464..895)
                     /locus_tag="MIV85_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBY2963064.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGSK"
     gene            complement(957..1094)
                     /locus_tag="MIV85_003771"
     CDS             complement(957..1094)
                     /locus_tag="MIV85_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBY2963065.1"
                     /translation="MNWYKIITDFYNNGNWTKEQVKTAVTKNKITASEYKEIVREDYI
                     A"
     gene            complement(1096..1395)
                     /locus_tag="MIV85_003772"
     CDS             complement(1096..1395)
                     /locus_tag="MIV85_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963066.1"
                     /translation="MIYLGNFMETDEQNIKYIGMIHYKPTLLSEEELKNGILIEKLPV
                     QQYVENKEAKLFINIDTKEVFYRYTDIKSSIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            complement(1392..>2549)
                     /locus_tag="MIV85_003773"
     CDS             complement(1392..>2549)
                     /locus_tag="MIV85_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963067.1"
                     /translation="NNFTSDNVEGALKEVFQNGVNAKNNVVTALNSKGAEVTTSDTWE
                     EIKNKIDIKEGRLDLRETILANSYSSYLVTNGAIKYIEKYSGSLKALEYEEPYFYAIK
                     GTHLIKINAIDESVIFDITLANANFSCICVTQEYLFISDNTKLYKINKLTGNEAQSIE
                     GSYYKLCTYGEFIYGIYGDETSSILHKIRISDMYIMLTKDMSSDRIYDFERGKFVCNN
                     NGIYATTEHSNSSGLTECYLTKINFDFSVAKSFRIGGYLYEKNIKFLNDFVFVSDSSR
                     SIEVESGKKSGLAKYDANLNLITYGGSDRYENFEIYNGYIYTFNSLSSSPFIKINLNT
                     LKEVNSYRTLINTNPQKGMFIINNIIFFIGGGIHRNILSKKVYSDEKGEEL"
BASE COUNT          821 a          439 c          244 g         1045 t
ORIGIN      
        1 tcataatctt ctttattatc acagaagaaa ctttcaatta atactgctgt aggctttgaa
       61 ctatttaaga tatataatct tttatctaat ttagcacctc tatttttaaa tactgtacct
      121 agtttatcac atattctagt tgcatactct aagcctttat tactataata taggacttct
      181 gaacctttac cttgaccgtt acttgcattt aaatgtaact ctataagtaa atcatatcct
      241 ccactattaa ctctaggtat tttataagac ttttcttcat tcttagtttt aaactgcttt
      301 tctgggcata ttattacatc taccttatgc ccttcttttc taaatgtatc tgctaatact
      361 ggtgcaagag atttgttgta ttgatactcg ttaactactc catcagcaga agtacatgct
      421 ccacttttta aaatactgtg tcctactgtt atacatattt tcattattta ctacctcctt
      481 taacatttaa ttcatctgtc atagtatcta ataaactacc tattttctct tttaatcgtt
      541 taggaactgg taatccacat aagtacatat tttttaatat acttacactt tcatatagaa
      601 taaataaaat agagaaaaat tcagatattc caagatgatt taatcgcaaa aaatcaaccc
      661 aatcttgtgg caacataaat aaaaagttaa actttgtaag aatgtcaact actgctagaa
      721 aaaatataca tgctatcatt gctacttttc ttattcctcc atttattcca aaagagctat
      781 taaactgatg tgtttttatt gctcttaagc aacctaacag tgtatcaaat gctattgcta
      841 atattactaa ttttataaat atatttgttg ctaaaaaaac tattgttacg ttcatatttc
      901 ctccttattc tgcattaaaa taagacttag aaattatcta agtctattta aaagaactac
      961 gctatatagt cctctcttac aatttcttta tattcacttg ctgttatctt attctttgta
     1021 accgctgttt taacttgctc tttagtccaa ttaccattat tatagaaatc tgttattatc
     1081 ttataccaat tcatactata tcaccccatt actcattaat tgaaatgtta aatctgctat
     1141 tgtttgttct gtagaattta ctttatcttc tatgctactt ttaatatctg tatatctata
     1201 gaaaacctct ttagtatcta tatttataaa taactttgct tctttatttt ctacatattg
     1261 ttgtactggc aatttctcaa ttaaaattcc attttttaac tcttcttctg atagtaaagt
     1321 tggtttatag tgtatcatcc caatatattt tatattttgt tcatctgtct ccataaaatt
     1381 tcctaaataa atcataattc ctctcctttt tcatctgaat aaaccttttt tgataatata
     1441 tttctgtgaa tgccaccacc aataaaaaaa attatattgt ttattataaa catacctttt
     1501 tgaggatttg tgttaatgag cgttcggtag ctattaactt ctttaagagt atttaaattt
     1561 atttttataa atgggctact agaaagtgaa ttaaatgtat atatatatcc attatatatt
     1621 tcaaaatttt catatctatc tgacccacca taagtaatca aatttagatt tgcatcatat
     1681 tttgctaatc cacttttttt accactctca acttctatgc ttctgctact atcagataca
     1741 aaaacaaaat catttaaaaa cttaatgttt ttttcatata aatatcctcc aattctaaaa
     1801 cttttcgcaa cactaaaatc aaaatttatt ttagttaggt aacattctgt aagaccactt
     1861 gaatttgagt gttctgttgt agcataaata ccattattat tacatacaaa tttgcctctt
     1921 tcaaagtcat aaattctatc agaggacata tctttagtta gcattatata catatccgat
     1981 attcttattt tgtgaagtat tgaagaagtc tcatctccat atattccata aataaattcc
     2041 ccataagtac atagcttata ataagaacct tctattgact gtgcttcatt tcctgttaac
     2101 ttatttattt tatataattt agtattgtca gatataaata aatactcttg agtaacacag
     2161 atacatgaga agttagcatt ggctaaagta atatcaaaaa ttacagattc atcaattgca
     2221 ttaattttaa ttaaatgtgt acctttaatt gcataaaaat agggttcttc atattctaat
     2281 gcttttaaac tcccactata tttttcaata tattttatag caccatttgt aaccaaatat
     2341 gaagaataac tatttgcaag tattgtttct cttaaatcta atctcccctc ttttatatca
     2401 attttattct ttatttcttc ccatgtatcg cttgtagtaa cctctgctcc cttggagttt
     2461 aatgctgtta ctacattatt tttagcatta actccatttt gaaaaacctc ttttaatgct
     2521 ccttctacat tatcacttgt aaagttatt
//
LOCUS       DAGQVA010000164         2525 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.170, whole genome shotgun sequence.
ACCESSION   DAGQVA010000164 DAGQVA010000000
VERSION     DAGQVA010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.170"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(133..741)
                     /locus_tag="MIV85_003774"
     CDS             complement(133..741)
                     /locus_tag="MIV85_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBY2963068.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(850..>2525)
                     /locus_tag="MIV85_003775"
     CDS             complement(850..>2525)
                     /locus_tag="MIV85_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBY2963069.1"
                     /translation="SLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYENIILNIPS
                     PILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFFDNREFKR
                     LNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFKLLTFRDI
                     TKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGISSDVLGV
                     TTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKRSRVRIIK
                     DLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIENLYKKGK
                     IIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIIDITERIVT
                     SISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGEILVGIYK
                     KDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKSLIEIQNG
                     KIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
BASE COUNT          801 a          419 c          199 g         1106 t
ORIGIN      
        1 taattataaa tttattaaat atgtttgtaa ttctataaag ttatttttat caaactaaaa
       61 attctataaa aaaataagat acatacctat aaaatacctt cctatagata catatcttac
      121 ctatataaaa acttattcta tataaaaacg ccataaaaaa tcttttgctt cttctgcata
      181 atctatattt atacgtttac tagtttttat atctaactca tctttactaa atactttttt
      241 tcctttatca tcataataaa aatcacttat atataattct tcacccatta tactcttact
      301 atttagactt ctatctattt ttaaagcttt gcaaagtttt cctggtccgt tagtaatatt
      361 ttttacttga tatttactca actcagtgta agctttgttg tatctattca tagatatctc
      421 atctaaagaa gttataggct ctacccctct tattaataca cactctggca cattttctat
      481 atttgcagat aaattcaagc aattatacat accataaatt aaataaacat atatatgtcc
      541 accatctaaa tataatggct tagttctatc tgtcttttta ttgccatata catgtgctcc
      601 tttatcattt acacccatgt atgcttctgt ctctatgatt ttggtaacaa ttactttatt
      661 ttcatatttc cttattagat atttacctaa tattgatttg gctaaatcaa ttccattttt
      721 tctaaaaaaa tccttttcca aaatttcacc tcataaaatt tatttaaaac gcatcaaata
      781 caactaaagt aataaataaa attaactctt attaatgtga tatatataaa caataaattt
      841 agacatttat tatttatata tatcaaaaaa ttctatctca aacttttcaa tattatcatt
      901 gtaatttgaa ttatcatata cttcttcaac aacctcttta attgggaata taacttttac
      961 attagttcct tctcctacct tactatctat gtaaatcttc ccattttgaa tttcaatcaa
     1021 tgattttgta aggcataaac ctataccact tccaaattca tttgatatac cactgttttc
     1081 aatttgttta aatcgattaa atatatcatt taatttttct ttgtctatgc ccactccagt
     1141 atcttttata attatctcta ctgtttcgtc ttttttatat atacctacaa ggatttctcc
     1201 tccttctaaa gtaaatttta tagcatttga taatatattt agtattattc tttctatcga
     1261 ttctgggtca agccctacca taacagtttc ttcatctgta tcaaaaatta aatctattcc
     1321 tttagactta gcataactac taatagatgt aactattctt tctgttatgt caataatatc
     1381 aaaattaact gctttaatct tatatatgtc tgacttaact tgagaaatat ttattatatt
     1441 atctattaat ctcaataatc taaacatatt ttgtttagtt atttttatat gttcttttag
     1501 tatatcctga aaatcaatta tttttccttt tttataaagg ttttcaataa gttgaactga
     1561 actatatata ttatttaaag gtgtcttaag ttcatgagat atattagcat aaaactccat
     1621 cttcatttgg tcatactgtc tttgttttat taatgctttt ttaagtcttt cagactctct
     1681 ttgcacactt aaatctttaa taattctcac tctacttctt ttctgtccaa agtataatgt
     1741 tcttgatatc atttttactt ctttaatgtg attattttca tttactatat ggatactctt
     1801 ctctctttct cctatattta aattgtttat gtattttttt actaatatat ttctatattt
     1861 ttgtgttgta actcctaata catcactaga aattccgaac aactctctaa aggctctatt
     1921 tgtatatagt actcttgatg tacttaaatc ctcaagaaaa atagcctctg gtataacatc
     1981 cagtaatttt tcatatatta ttttttgttc atttactgtt ctaagaatat ttatctcttt
     2041 agttatatct ctaaatgtaa gcaatttaaa gagtttatta tctgaccaat agtctccaac
     2101 tctaacttct tcaacatgct cttcaccttc tgagtcagac atcacaaaat taactataca
     2161 gtttgctgtg tcattgtaac ttactatttc agctttcttt tcttgtgtta gatttaatct
     2221 tttaaattcc ctattgtcaa agaaatctat gttaaaagtt tcaaaatatt gttctaatgt
     2281 catatcgact aaatcacttg aaacacattt aaaactcttt tcatattttt tatttatact
     2341 tattacctta ttcttcttta tgccaccttc agcacttctt acaagtatag gagatggaat
     2401 atttagtata atgttttcat agtctttatt tatatttctt atttcttcat ctattttgat
     2461 ttcatttgta atatcattta aacttattaa gtaattgctt tcatctttat tattacttaa
     2521 actta
//
LOCUS       DAGQVA010000165         2523 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.171, whole genome shotgun sequence.
ACCESSION   DAGQVA010000165 DAGQVA010000000
VERSION     DAGQVA010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.171"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(118..1014)
                     /locus_tag="MIV85_003776"
     CDS             complement(118..1014)
                     /locus_tag="MIV85_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBY2963070.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKKNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            1155..>2523
                     /locus_tag="MIV85_003777"
     CDS             1155..>2523
                     /locus_tag="MIV85_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBY2963071.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIAKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFNWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVC"
BASE COUNT          867 a          351 c          302 g         1003 t
ORIGIN      
        1 tttcacattt aactatacaa gtagtcttac tcatttatat cctatgcttt attaatattt
       61 attaagaaaa attcaaagat ttaaaaatat atattttcta taaagtatat ttatgaatta
      121 tttcatatct tcttttaaaa taacattact aacttctcta tgttcatttc tatacttagt
      181 tggagatata ttataattct ttttaaataa gcgactaaaa taatttatgc tatcaaagcc
      241 acatctcata gcaatttctg tcatatttaa atctgtttcc tttaaataat atatagcttt
      301 atcaagcctg attccattta taaaatcgat tgtagtctta cctgttattt gcttaaatgt
      361 tctacaaaag tgatgtgcac tcaagttcac acgactagca agttctttta atgtaatttt
      421 atccatatat ttttcttcta tcaaatcaaa gatacattca aatttttcta aagaatactt
      481 tctttttata aattcatctt cagaatatat tttatcaata tgacttctta ataagagtac
      541 tattaattga tagatattag cttttataga taactcatat ccaacttctt tattgtgata
      601 ttcatcaagt atagttgtaa tacattttaa aatcagagaa tcattttgaa ttaaattatt
      661 aaatacaata tgatttaaag ccaatggtgc taagtacttg gtttgtaaca aatcaacttg
      721 attactaaaa aggaatgtgg gttcaatacg aatactatag aattttaaat tatctgataa
      781 gctttctaaa taatgtaatt cattactgtt tgctattaca atatttccag gcactacctt
      841 aaaattatcc aatccacatt caagatatgc tataccatca ataaaataat atatttgtag
      901 atgctcatgc caatgtcttt taaagtttgc tcctttttta atgtcatcct ttaaaaaaat
      961 atctataaag ttttcttgac ctttcctgtt aaaatatgta tttttatcct tcattattcc
     1021 cccctcatca aaatagtgct aattataagc aatatagtta ttgtattcat tatttcatat
     1081 cgctattata taaaatgtaa ctatcattgt aaacattaac ataatgcagt cattataata
     1141 aggaggtaat aaaaatgaca aactctttta aaaaagatga taatagaaaa aaaatcacag
     1201 ttttatttgt agtcattgcc atgactttta tggcaacatt agattctagt attataaatg
     1261 ttgctctccc agttcttgca agcaaactaa atgtatctct agcatctatt gaatgggtaa
     1321 tagcaagtta ctcaattatt atttgttcaa cactattatt ttttggaaga cttggagata
     1381 ttattgctaa atcaagagta tttcaagtag gtactattct ctttacatca gcttcattac
     1441 tatgtggatt aagtaattct ttaactttac ttatagtttg ccgctttatt caaggaatag
     1501 gcgcttctgc ctacatggca aacaatcatg gaattatcac agaactattt ccaaaagaaa
     1561 gcagaggaaa agccctaggg attttagtta ctgcagttgc tattggaaat atggttggac
     1621 catctgtggg aggatttatt ttgtcaatat ttaattggaa tgttatattt tttataaata
     1681 ttccaatcgg tcttattgta atctttttaa atacaaaatt tcttcctaat agtaaaaaat
     1741 cttcagaaaa tatggataaa actggtgcta tacttcaatt tttaggaaca acattatttt
     1801 ttagtgctct aattagtgct caacaaacag gattactaaa tccatatata ttaattgcac
     1861 tattattatc aattattttt attatattat ttttgatatt agaaaaaaaa catcctcaac
     1921 cgcttcttga ccttgaaatt tttagaaatt ttaaattttc attgaattta atttgtgctc
     1981 ttacatcatt catttgtatt gcatcatcaa gtattttaat tccattttat ttacaaagta
     2041 ctatgaaact tccccctatt caagcaggtt tatttatgat actatcacct ttgattttag
     2101 ccattttttc acctatattt gggaatatat cagataaaat taagtcagaa aaaattattt
     2161 taattggtct tctcgttatg agttttggat tctttctaat gtcaagattg aaagaaagtt
     2221 ctgcccttat tttatttgta atttatatat cgataatatc aataggacaa gctatatttc
     2281 aacctgctaa caatgctttg ataatgtcaa gctgttctag aagtaagcta ggagttgtag
     2341 gaagcataaa ttcccttgta agaaatttag gacaagttat aggtattact atttctacaa
     2401 cacttttata taattttatg agtattaaag ctggatatag ggtcaatgat tatgtgatta
     2461 ataatgataa aatatttgta tttggaatga gaaatgttta tattattgtt acacttgttt
     2521 gct
//
LOCUS       DAGQVA010000166         2290 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.173, whole genome shotgun sequence.
ACCESSION   DAGQVA010000166 DAGQVA010000000
VERSION     DAGQVA010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2290
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.173"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     misc_binding    52..282
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            390..1871
                     /locus_tag="MIV85_003778"
     CDS             390..1871
                     /locus_tag="MIV85_003778"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBY2963072.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            1881..>2290
                     /locus_tag="MIV85_003779"
     CDS             1881..>2290
                     /locus_tag="MIV85_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBY2963073.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILG"
BASE COUNT          888 a          266 c          366 g          770 t
ORIGIN      
        1 cttgactttg tctgttttat aaactagaat aattaataat attaagaata ttgaaaggca
       61 ttgattagga agagtaaatc tgaatcgatt accagagaag gaaactacta gctgaaatgt
      121 ttccctaatt agaaggattg aaaactacct aggagcttct atccgaagtt atcttaatga
      181 ttttagtagg aatagacgtt tttattactt gcgttaaagt atcaagtgga ttttttaaat
      241 caatttgggt ggaaccgcgg gaaacagatt ctcgtccctt ttttagggat gagggtcttt
      301 ttttattacc taaattcagt ttttaaaata ttctgtatct aatttaatta gctaattaaa
      361 aatttaaaat atatggagga ttataaaaaa tgtattattc aagtacgaga ggcaccgaag
      421 aaaaagtaac tgcatcacaa gcaataataa aaggaatatc aagtgatggt ggtctttatg
      481 ttccaagtga atttcccaat gtaaaaaatg aacttataaa tttagtaaat ttaacgtatt
      541 ctcagatagc attttttgta cttagtaaat ttttatgtga ttttactgaa gatgaaatta
      601 aaaattgtat agaaaatgca tatgatgaaa agtttgattg tagtagtata gctccattaa
      661 ataaagtaaa tgatacttat ttcttagaac tatatcacgg tccaacttta gcatttaaag
      721 atatggcact tactataatg cctcatcttc ttaaaacatc tataaagaaa gataatttag
      781 agaaagatgt tgtgattctt actgctacat ctggagatac aggtaaagct gcacttgagg
      841 gatttaaaga tatagataaa ataaagataa ttgtattctt cccagaagat ggtgtaagcc
      901 cagtacaaaa acttcaaatg aaaactcaaa ctggaaaaaa tacatatgta gttggtataa
      961 aaggaaattt tgatgatgca caatcaggtg taaaaaagat tttttctgat aaagaattta
     1021 atcaaaaact attggataat aattatatat tatcttctgc aaattcaatt aatataggaa
     1081 gacttcttcc acaagttgca tactattttt attcatatat gaaattagtt agcaatagtg
     1141 atataaattt aaatgataaa ataaattttg ttgtcccaac tggtaatttt ggtaatattc
     1201 tagctggata ttatgccaaa caaatgggtc ttccaataaa caaattaata tgtgcatcaa
     1261 atgataataa tgttctttat gatttcttta aaactggtgt atatgataaa aatagaacat
     1321 tgaaattaac tacttctcct tctatggata tattaatttc aagtaattta gaacgattac
     1381 tgtttgaaat atcaaataga aatactgata ttgtaaataa gcttttatca gaccttagtg
     1441 ataaaggagt ctacaaaata agtgatgata tggaaaaaaa tttagcctca ttctatggag
     1501 aatattcaaa tgaagaagaa gttaaaagca cgataaacaa tgtgtttaaa aattataatt
     1561 atttgataga tactcatact gctgttgcat acaattgtta tgaaaaatat aaaaaagaaa
     1621 cttctgataa cacaaaaact gttattgtaa gtactgcaag tccattcaag ttttctgaag
     1681 atgttctaaa gtctatagat tgtgatttta aagaccttga tgactttgct ataattgata
     1741 gattatcaag tatttctaaa atagatattc caaaacctat taaaaatctt aaaaatgcag
     1801 aaatactaca taaagatatt tatgaaaaag atgaattaaa actagctata aaaaaattct
     1861 taaaggtata ggtgattatt atgttagaga ttatagttcc tgcaacaagt gctaatatag
     1921 gtccaggatt tgattgtctt ggaattgcgt taaatatata caataaattt tatgttgaag
     1981 aaattgaaag tggtcttgaa atagaaggtt gtgaagatgc ttacaaaaac gaaaacaact
     2041 tagtttatac atctatgaag tacttttttg atagagttaa accagaaaaa atacctgctg
     2101 gtatcaaaat aaaaatccaa agtgaagtac ctatatgtag aggtcttggc agtagtgcct
     2161 cttgtatagt agctggagtt atagctgcaa atgctctatc aggtgctaat ttagataaaa
     2221 atcaattact aaatatagct tcagaaatag aaggtcaccc agataatgtt gctcctgcta
     2281 ttttaggaaa
//
LOCUS       DAGQVA010000167         2249 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.174, whole genome shotgun sequence.
ACCESSION   DAGQVA010000167 DAGQVA010000000
VERSION     DAGQVA010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2249
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.174"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            105..293
                     /locus_tag="MIV85_003780"
     CDS             105..293
                     /locus_tag="MIV85_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963074.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            complement(703..1287)
                     /locus_tag="MIV85_003781"
     CDS             complement(703..1287)
                     /locus_tag="MIV85_003781"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963075.1"
                     /translation="MKGEYNKEKEKVIKFNSNKDKSKINKYTDYYNTLNSTLMEKNKC
                     IGDNWFLATTSEEVGNMNEEEKRILETEKRILETEKRVHQNNKEVKESIDKQFNDIKG
                     IFKEYKNDLDKDRIELKNDLARERIELKSDLKEAINEHKKVTEKDVSEIKNSIKGIED
                     RIDSTNKWIIALCITTIIGIATMAITIGISIWPK"
     gene            complement(1290..1781)
                     /locus_tag="MIV85_003782"
     CDS             complement(1290..1781)
                     /locus_tag="MIV85_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963076.1"
                     /translation="MAYENGTNLVAYFPNCIKKYEKDNKIFEKTILLLNLYMQMPTWP
                     HCIHEFKAKANEILGEDPEFIGEYGIKLKDFYNEGENVNISQNFKNDLYTFSNSTYDI
                     LDNSYIQRINPIGLYSISSLARENDFILKLFRNDKKSLELELSKSEIQSIIEHLESMI
                     EEE"
     gene            complement(2031..>2249)
                     /locus_tag="MIV85_003783"
     CDS             complement(2031..>2249)
                     /locus_tag="MIV85_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBY2963077.1"
                     /translation="KISATVVGWGYNDGKILICDIKDYVPGQTQNLYVVGGVACEKIG
                     SMTKEKFTMIKGNDRFDTLYKALEFINK"
BASE COUNT          733 a          327 c          220 g          969 t
ORIGIN      
        1 ttctatattg caataaaaaa cattgtttta aatatatata cataggtata tactaaatat
       61 gttaaactta attatggaaa atataaaatg aaaggaataa aaatatgact aagactatat
      121 tatgtgatta ctgtaataaa ggaataaata aagatgataa taagtatatt acttttcata
      181 agaaaagtca tatgaaaact aacatttgta ttaattgtgc attaaatttg atagataaag
      241 ataaattaaa tgaaaatatt ataaataatc aacatgatta ttcaaagaaa tgaaaaagca
      301 ctctccataa tgaagaatgc tctatataat aatgtttgac ttagtaaaga tgtgttgggg
      361 ttacatattt acttttttat tatatcatat aactttgtgt atgaaaaaga atttaaatca
      421 attttaaggt gtgttgagta atattcttga tagtttatat gttgatgaat ttcaaaaaaa
      481 taagcactct tataaaaaga gtacttttgg tatatattca agcatttatc taatacaatt
      541 atagcatgtc ttatgtttta gtatgataat tttcgttcgt tttattatta caggttatac
      601 tatagtttta tgtatcctgt taatattttt tactattttt tcaatgtttt gtttaagtat
      661 aaaaagagat aactatttta attctagtta cctctttttg tgttactttg gccatataga
      721 tatacctatt gtaatagcca ttgtagcaat tcctattata gtagttatac ataatgcaat
      781 aatccattta ttagttgaat caattctatc ttctatacct tttatactat tctttatttc
      841 acttacatcc ttttctgtca cctttttatg ttcgtttata gcttctttta aatcgctttt
      901 taactcaatt ctttctctag ctaaatcatt ttttagttct attctatctt tgtctaaatc
      961 attcttgtat tctttaaaaa taccctttat gtcattaaat tgcttatcta tactttcttt
     1021 tacttcctta ttattttgat gtactctttt ttcagtctct aatattcttt tttcagtttc
     1081 tagtattctt ttttcttctt cattcatatt acctacctcc tctgaagtag tagctaaaaa
     1141 ccaattatct ccaatacatt tatttttctc catcaaagta ctatttaaag tattataata
     1201 gtctgtatat ttgttgattt tacttttatc cttgttggaa ttaaacttta ttactttttc
     1261 tttttcttta ttatattcac ccttcataac tattcttcct ctatcataga ctctaaatgt
     1321 tcaattattg attgtatttc tgatttagat agttctaatt ccaaagattt tttatcattt
     1381 ctaaatagtt tcaaaataaa atcattttct ctagccaaag aagatataga atataagcca
     1441 attggattga ttctctgaat atatgagtta tctaatatat catatgtact atttgaaaaa
     1501 gtatacaaat catttttaaa gttttggctt atatttacat tttcaccttc attataaaag
     1561 tctttcagtt taattccata ctcacctata aattctgggt cttctcccaa aatttcattt
     1621 gctttagctt taaattcatg aatacaatgt ggccaagttg gcatctgcat atataaatta
     1681 agtaatagta ttgtcttttc aaatattttg ttatcctttt cgtatttttt tatacagtta
     1741 ggaaaatacg ctaccaaatt agtcccattt tcataagcca tcttaactcc ccctaaaata
     1801 atattattta atactattct acattataat tactttcatt gcactattat tttttattcc
     1861 tcctcctacc acttattgct atatactcaa ctgctcttca tatacctgat tttttaaagt
     1921 ttgtagatga cttatggtta tatttaatat atcatttttt attttataaa ttgttgtgat
     1981 actgtcataa aattgtagtc aaaatgtaaa atatattaac tctattgatt ttatttattt
     2041 ataaactcca gtgctttata aagtgtatca aatctatcat taccctttat catagtaaat
     2101 ttttctttag tcatagaacc aatcttctca catgctacac cgcctacaac ataaagattt
     2161 tgcgtctgac ctggcacgta atcttttata tcacatatca gtattttccc atcattataa
     2221 ccccaaccaa ctacagttgc agagatttt
//
LOCUS       DAGQVA010000168         1986 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.175, whole genome shotgun sequence.
ACCESSION   DAGQVA010000168 DAGQVA010000000
VERSION     DAGQVA010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.175"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            84..200
                     /gene="rrf"
                     /locus_tag="MIV85_003784"
     rRNA            84..200
                     /gene="rrf"
                     /locus_tag="MIV85_003784"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            207..281
                     /locus_tag="MIV85_003785"
     tRNA            207..281
                     /locus_tag="MIV85_003785"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:239..241,aa:Asn,seq:gtt)
     gene            286..360
                     /locus_tag="MIV85_003786"
     tRNA            286..360
                     /locus_tag="MIV85_003786"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:319..321,aa:Glu,seq:ttc)
     gene            366..441
                     /locus_tag="MIV85_003787"
     tRNA            366..441
                     /locus_tag="MIV85_003787"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:399..401,aa:Val,seq:tac)
     gene            447..523
                     /locus_tag="MIV85_003788"
     tRNA            447..523
                     /locus_tag="MIV85_003788"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:481..483,aa:Asp,seq:gtc)
     gene            534..608
                     /locus_tag="MIV85_003789"
     tRNA            534..608
                     /locus_tag="MIV85_003789"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:566..568,aa:Thr,seq:tgt)
     gene            623..707
                     /locus_tag="MIV85_003790"
     tRNA            623..707
                     /locus_tag="MIV85_003790"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:657..659,aa:Tyr,seq:gta)
     gene            717..790
                     /locus_tag="MIV85_003791"
     tRNA            717..790
                     /locus_tag="MIV85_003791"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:749..751,aa:Gly,seq:tcc)
     gene            801..877
                     /locus_tag="MIV85_003792"
     tRNA            801..877
                     /locus_tag="MIV85_003792"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Arg,seq:tct)
     gene            887..962
                     /locus_tag="MIV85_003793"
     tRNA            887..962
                     /locus_tag="MIV85_003793"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:920..922,aa:Gln,seq:ttg)
     gene            974..1049
                     /locus_tag="MIV85_003794"
     tRNA            974..1049
                     /locus_tag="MIV85_003794"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1007..1009,aa:Lys,seq:ttt)
     gene            1052..1140
                     /locus_tag="MIV85_003795"
     tRNA            1052..1140
                     /locus_tag="MIV85_003795"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1086..1088,aa:Ser,seq:tga)
     gene            1158..1248
                     /locus_tag="MIV85_003796"
     tRNA            1158..1248
                     /locus_tag="MIV85_003796"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1192..1194,aa:Ser,seq:gct)
     gene            1257..1333
                     /locus_tag="MIV85_003797"
     tRNA            1257..1333
                     /locus_tag="MIV85_003797"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1291..1293,aa:Pro,seq:tgg)
     gene            1419..1494
                     /locus_tag="MIV85_003798"
     tRNA            1419..1494
                     /locus_tag="MIV85_003798"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1452..1454,aa:Trp,seq:cca)
     gene            1555..1631
                     /locus_tag="MIV85_003799"
     tRNA            1555..1631
                     /locus_tag="MIV85_003799"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Pro,seq:tgg)
     gene            1638..1714
                     /locus_tag="MIV85_003800"
     tRNA            1638..1714
                     /locus_tag="MIV85_003800"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1672..1674,aa:Ile,seq:gat)
     gene            1718..1793
                     /locus_tag="MIV85_003801"
     tRNA            1718..1793
                     /locus_tag="MIV85_003801"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1751..1753,aa:Phe,seq:gaa)
     gene            1801..1877
                     /locus_tag="MIV85_003802"
     tRNA            1801..1877
                     /locus_tag="MIV85_003802"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1835..1837,aa:Met,seq:cat)
BASE COUNT          517 a          452 c          531 g          486 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaatgtggtt ataatagcgg aggagataca cctgtttcca
      121 ttccgaacac agaagttaag ttctctagcg ctgatggtac ttggtgggaa actgcctggg
      181 agagtaggac atagccacgt gaatgttcca aggtagctca acggtggagc aaccggctgt
      241 taaccggtag gctgtgggtt cgagccccac ccttggagcc attatggctc gttggtcaag
      301 aggttaagac accgcccttt cacggcggta acaggggttc aattccccta cgagtcacca
      361 tttgtgggat catagctcag ctgggagagc acctgcctta caagcagggg gtcacaggtt
      421 cgagccctgt tggtcccacc atttgcggcc tggtagttca gttggttaga atgccagcct
      481 gtcacgctgg aggtcgaggg ttcgagcccc ttccaggtcg ccaaaataaa aatgctggtg
      541 tggctcaacg gtagagcagc tgacttgtaa tcagcaggtt gtaggttcga ttcctatcac
      601 cagctccatg taaaactaat acggaggatt tcccgagcgg ccaaaggggg cagactgtaa
      661 atctgttgtc atcgacttcg gtggttcgaa tccaccatcc tccaccaatt aaatatgcgg
      721 gtgtagctca atggtagagt tctggccttc caagccagct gtgagggttc gatccccttc
      781 acccgctcca aagaaagcgt gggtgcatag ctcagctgga tagagcaacg cccttctaag
      841 gcgtgtgtcc ggggttcgaa tccctgtgcg ctcaccacat atatattggg gattagccaa
      901 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      961 caaataaaaa tatggtctat tagctcagtc ggtagagcac ctgactttta atcagggtgt
     1021 cccgcgttcg agtcgcggat agatcaccaa tggagaggtg tccgagtggt ttaaggagct
     1081 ggtcttgaaa accagtgact tcgaaagggg ccgtgggttc gaatcccacc ctctccgcca
     1141 aaaaaatgac tgaatttgga gaagtactca agtggctcaa gaggatcccc tgctaaggga
     1201 ttaggctggg taaccggtgc gagggttcga atccctcctt ctccgccatt caaaaacgag
     1261 gtgtagcgca gtttggtagc gcacatggtt tgggaccatg gggccggggg ttcgagtccc
     1321 ttcacctcga ccaacttaag cttttagttc agttggttag agtgcccaac tcatggctag
     1381 taattctagg gtttgagtcc atgaaggtta ttcttcatag gggtgtagct cagttggtag
     1441 agcgtcggtc tccaaaaccg tgcgccgggg gttcgagtcc ctccacccct gccaaataaa
     1501 aaggacttga aaaaagttgg attttagagt agtataagat agtaaataag atttcgaggt
     1561 gtagcgcagt ttggtagcgc acatggtttg ggaccatggg gccgggggtt cgagtccctt
     1621 cacctcgacc aagaaaaggg cctatagctc aggtggttag agcgcacgcc tgataagcgt
     1681 gaggtcgctg gttcgagtcc agctaggccc accatttgcc cagatagctc agtcggtaga
     1741 gcaggggact gaaaatcccc gtgtcggtgg ttcgattccg cctctgggca ccaggaatac
     1801 ggcggtatag cttagttggc tagagcgttc ggttcatacc cgaaaggtca taggttcgac
     1861 tcctattacc gctaccatct aactatatca ataaagaact ttgaaaatta aacagtaggt
     1921 taatttataa acaagaaaca aaccataaag ccagatattt tgataacaat agtatctgag
     1981 cctgat
//
LOCUS       DAGQVA010000169         1898 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.176, whole genome shotgun sequence.
ACCESSION   DAGQVA010000169 DAGQVA010000000
VERSION     DAGQVA010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.176"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     misc_binding    786..1049
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1200..1751
                     /locus_tag="MIV85_003803"
     CDS             1200..1751
                     /locus_tag="MIV85_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBY2963078.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          800 a          180 c          280 g          638 t
ORIGIN      
        1 ataatcagca ttataaatcc attacaagta gaagcagaag ctattattga gtctagtgta
       61 tacatttctt caataaaaga gaattataca tatgataata ctaaatttaa aactattaaa
      121 tctaaaagta gacataaaag taggaaatat aataaaagta aagtaaagtt gaaaaaacga
      181 agtataagaa ctaaaaagta tggatatcaa actataaata aatataaaag acaaaacgca
      241 agaagacata atatcctaac aaaattaata ttgttcataa tagtcatatt tttggttata
      301 gttttagtag tgctaatatt tattaaaaga aagaagaaaa aattttacta aaaataatta
      361 aaagaatatc atttttttaa tcattggtat ctatttaata atatgatgta attaaaatgg
      421 agtaatattc tgtttcaaag gaggcatata aatacaggaa tgagtattaa atgatggtta
      481 attaagtaaa tttattgata aatgtactta attaactttg aagaatttaa ttcctcatga
      541 atcaaaatat aaaattacat caacagttat tcacaaaatt aatataagaa gaattagagc
      601 caaagagcag actattagac cattaaagta attattcata gaattttgta tatgaaaaga
      661 aatgtatagt ataatttact ttttttataa aaaatagatt acaaaatata ttttttataa
      721 aaaggtattg acatttttta gaaaaaagaa tattattatt ttaaaacaaa attcaataca
      781 ataaattaaa tcctatgaca aggaagagta gttaaattta ggttcagtat agagagctga
      841 ggatggtgga atcttagcaa gaaaaaattt gatgaatggc ccttagagga ataaattgaa
      901 atcatagttt tgagagtaga ctttatcgtc agtcgcacgt tatagcgaat aaggtatgta
      961 agtacctgat aatgagatgt atgaaaattg aattttatat taatttttat ataatttagg
     1021 tggcaacgcg gataatctcc gtcctattag tttaggacgg agttttttat tttactgaaa
     1081 atttaaaaga tagaaggtgg tgagaaagat gttatgaatt tcaaaagcta aagatgatga
     1141 tatagtaggt tggcaaaaaa ataaattgaa aattaaaaaa ataggaggaa gtacaaaaaa
     1201 tgaaaacaaa tacaaaaaaa ttaactttaa atgcaatact tttagcgatg ggattattaa
     1261 tacatcaaat cacaccagct ataggattac caatgaagcc agatgtacca ctagcaatgt
     1321 tatttgtaat attggtttta aatagagatg attataaaac ttgtttgata gcgggtatag
     1381 taacaggaat atttacagca cttacatcaa gttttccggg aggtcaaatt cctaatgtaa
     1441 tagataaaac tcttacagca aatatagtat ttttattaat gaatattagt tataatatgc
     1501 cttttataaa aaaattagct aagaaaacac aagatactgt agtagttgca ataataatgc
     1561 caataggaac tcttgtaagt ggaactatct ttttattagc agctcaagct atagttggtc
     1621 ttccaggggc ttcatttaca gctttattct tagcagtagt attaccagct gttttaataa
     1681 atctagttgc aggaatattt ttattcaaga ttgttagtct atcaataaga agagttagtt
     1741 atcaagctta aacacgaaat aatattttac tttataaagc attataataa ctaaataaca
     1801 taagaataaa gtagattata actattttat tcttatgttg tttaaagatt tggtattata
     1861 tatttatttt taataaaata tttatatagt accaatta
//
LOCUS       DAGQVA010000170         1881 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.177, whole genome shotgun sequence.
ACCESSION   DAGQVA010000170 DAGQVA010000000
VERSION     DAGQVA010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1881
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.177"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(416..805)
                     /locus_tag="MIV85_003804"
     CDS             complement(416..805)
                     /locus_tag="MIV85_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2963079.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          614 a          354 c           99 g          814 t
ORIGIN      
        1 ttaacacttt tatctctatc tctttaatat cttatattaa tcctttattt ttattttttc
       61 aatatcatca ttaattccta tttattttat catcttaaat acgaaaacac tgtgtcatat
      121 ttgcaaaata tatattatca tctatattaa agcttcacaa tttatattta aaaattctct
      181 ttaattacac tacctctatt taaaaagcta ccttaattat acttataagt aaaggtagct
      241 ttttaaattt aattaaatag aatatccact attaattttt atttaattta tttagattca
      301 cattatagta tcataatcca cttataatca tttgtcatat tacttaagta gactaatata
      361 ttacataaat acacttacat acactttata ttgatgctat aagaaatacg tttgcttata
      421 cgtctttctc ctcttctttt agatttttta tccactcttc aataagtaag atatcatctt
      481 tgctcaaatt aatattttca tgtaatgaca acaataaact ttttatagaa gaatcatgaa
      541 tatttctaaa aaaatctctt gtctcaactc ctatgtattc cttttcttta attaaaactt
      601 cataatgcgt atatttatct atcttttgag aatttagaaa tctttttact actaatctag
      661 ataaaagagt caaagttgtc gtttgtttcc attgatattt ttgctccatt cctaaaacaa
      721 tatctctaga tgttactttg gaatctgatt tccatataaa tttcattatc tttaattctg
      781 attgtggcaa cttttttata gtcatgataa aaccttgcta ctcagaatat agacaagcaa
      841 tatccataat aaaatttttc gattaaatac atcttatacg gatttatata agctcagact
      901 tataagatat ttttcaatct taatcctaaa tttagctatt tgtacacggt aaatatatat
      961 aaataatgtc aaaattctct tgtattatat tgcttaattt tatgaaatat tttgtactca
     1021 gctatctatt ttggatactt gtccagtagc tctcctttct tttaaactct ttgattttaa
     1081 atatttgtat ttcagtaaat cctacttcct aaatttttta tttactacaa cttattactg
     1141 aacttcctac ttcctaaact ttttatttac tacaacttat tactgaactt ctcacttact
     1201 aaatttctta cttactataa attataacta aacttctcac ttactaaatt tcttacttac
     1261 tataaattac tactaaactt cctactttct aaatttctta cttgctataa attattacta
     1321 aacttcctac tttctaaatt tcttacttgc tataaattat tactaaactt cctactccct
     1381 aaatttctta cttgatacaa attattacta aacttcctac tccctaaatt tcttacttgc
     1441 tataaattat tactaaactt cctactccct aaatttctta cttgctataa attattacta
     1501 aacttcctac tttctaaatt tcttacttgc tacaaattat tactaaactt cctacttcct
     1561 aaatttctta cttgctataa attattacta ctaaacttcc cacttcctaa gtttcttact
     1621 tgctacaaat tattactaaa cttcctactt cctaaatttc ttacttacta ctacttataa
     1681 ctaaacttcc cacttcctaa atttcttact tactactact tataactaaa cttcccactt
     1741 cctaaatttc ttacttacta ccacttataa ctaaacttcc cacttcctaa atttcttgct
     1801 tactaccact tataactaaa ctttttactt cttaaatttc ttgcttacta ccacttataa
     1861 ctaaactttt tacttcttaa a
//
LOCUS       DAGQVA010000171         1860 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.178, whole genome shotgun sequence.
ACCESSION   DAGQVA010000171 DAGQVA010000000
VERSION     DAGQVA010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.178"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(1..711)
                     /locus_tag="MIV85_003805"
     CDS             complement(1..711)
                     /locus_tag="MIV85_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963080.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKNTAVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
BASE COUNT          739 a          251 c          147 g          723 t
ORIGIN      
        1 ctaacataat acatctccca atacatatgt taattttttc tttaaatcag ccattctata
       61 tttactaact ggtacatctt catcattaat aaccgcagta tttttacata taaattgaat
      121 atactccaaa ttaattaaat agctcttatg acatctaaaa aaattatatt tttctagctc
      181 taattctatt ttatccatac tatttttagt ataataagta tcatttttag tatgtatagt
      241 caaaaccttt ttcctaacct ctatatacat aatactatta attaaaattt tattgattat
      301 acctttattt tctatcagca taaaattttc tctttttttt ataatatccg atatacaact
      361 caaaatactt tcatttaaat ctccaaaatc tataggcttt aataaatatc tataagccct
      421 taccttatag ccttcctgta tgtaatcaac tattgaagtt ataaatatta tttcagaagt
      481 atcattagtt tctctaatta ttttagccac atccatgcct gttagttgaa gcattttaat
      541 atctaaaaaa aatatatcaa taccttctaa atttgtttcc aataattctt ctcctgaatt
      601 aaactcaaat agttcaattt gactagaaat accctctaag gactttaata tacactctct
      661 taaaaaagct atttgtgtaa tatcatcctc acagataact attctataca taaacacccc
      721 tccttagaca ttagatctga aaacaaataa aatatcaatt tataaataat tatttagtta
      781 tacaactaac atggtcatca aatactatta ttcacttaaa aaatcacccc ctatttttag
      841 tatgttaaca acaaaataag aagatatctt agatttttaa aaacaattaa tacttaatgt
      901 agttttgtat actatttata ggtaattttt tatatcattt taaacattaa aattattgat
      961 gtttaagaac tattatattg atagtaatat ataattaatg atatcaaaaa tttttaatta
     1021 gacttctctc ttattcaaga tttttctata taaaatctaa gaataaatag aaaactaaca
     1081 tctaaccttt tattttttat tttcgatcta tttacttgaa ttttaacata aatctatctt
     1141 ttagtatata ttaatcatgc tgaatttgtg atgacatgta tacaaaatat cgtttagtat
     1201 tttctaataa aaaatattac tgaaattaaa aatctacaat agcatttaac aagtaaaaac
     1261 atgtttacac aaatatataa tttaaggtct ttaaaataga gtatgtatta ttctaaaaat
     1321 tagttatagt tatcacataa aaatagaaaa gaattttcaa aagatttaaa gaacatacat
     1381 acttcaattg cagaagatgt aatgttaagt gaactagcat tcttcgagga aaaatagact
     1441 caaaaaatta gaaaatagaa tcaggtttta gatgatttaa gtatttattt tcaaaaaaga
     1501 aatttgattc taagttaata aagaaatatt taaaaaaatc aaaaaatttt cttaaataag
     1561 taataggttt tgtaaaaatg gaaaaatatc aaaataagac tatgattttt aaaactatag
     1621 ccttatcaat aaatttttat ttaaagaaca cacataaata tttttaaacc taatttatgt
     1681 gaagttttat gtatttttta tataagtagt attctaatct tactcatcta atataccaaa
     1741 aagactgtaa gtaagttcac ttttatgcaa acttacccac aatctctttt acacattaat
     1801 tctatttatt aaaattaaaa atatttactg ctattctacc caataaagat gatactgttg
//
LOCUS       DAGQVA010000172         1824 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.179, whole genome shotgun sequence.
ACCESSION   DAGQVA010000172 DAGQVA010000000
VERSION     DAGQVA010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1824
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.179"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..861
                     /locus_tag="MIV85_003806"
     CDS             <1..861
                     /locus_tag="MIV85_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBY2963081.1"
                     /translation="VVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDE
                     NNLIAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDL
                     ETKIGTVNTKIDTTKTELTNNLETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQ
                     TITIDDWVEDAENGFKATVTHSLLTQRIVVNIIDVTTKENVVTNFKIIDDNSIEIRSE
                     VKAELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRLINIEEKVNGGLSSIA
                     TSVNELITYC"
     gene            876..>1824
                     /locus_tag="MIV85_003807"
     CDS             876..>1824
                     /locus_tag="MIV85_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963082.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWYTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQIMGTYYSMY
                     GGGATDIRLVGGAWDNEQGLLSRIIVAGGGGGSYYPSTGGAGGGLEGGTGYSSNDRYR
                     PGGTQYQGGIGRVNTENGSFGKGCSVKDSTGEGGGGGWFGGAGMNGVGAGGGGSSYVL
                     TKDSYKPTGYTPTSEYYFDNIVMTPGGNTAGAYGYAQITLLQSLPFLNISSYNSTQAT
                     FKADHTDPTLLTKIEYFIDDVLKETITTDLTEEKTINYTL"
BASE COUNT          671 a          233 c          383 g          537 t
ORIGIN      
        1 gtggtatggg aaggcaatat tggaaataca actacagatg aaactgcacc aaattgtata
       61 atattagaga gtttaatacc atcaagtgta ggcggattta tgataagaga aataggatat
      121 ttagatgatg aaaataattt aattgccatt tctaaataca aagagtgtta taaaccttct
      181 atagaacaag gtgcagtggt agacatgaag gttaaaactg tgcttattgt atctaatgta
      241 aataatatag aacttaaaat tgacccaaca ataatctttg caacactcaa agatatacaa
      301 gacttagaaa ctaaaatagg tactgttaat actaaaatag atacaactaa aacagaatta
      361 acaaataatt tagaaactgc taaaacagag ttaaatacta gaattgacac agaaaatgag
      421 aaacaaaata ttaaaattga ccaacttatt gcaggtggct ctaatgtggc atctactcaa
      481 acaataacaa ttgacgattg ggttgaggat gcagaaaatg gattcaaagc aactgtaaca
      541 catagtttat taacacagag aatagttgta aatattatag atgttactac aaaagaaaat
      601 gtagttacaa actttaaaat tatagatgat aattctatag aaattagaag tgaagtaaaa
      661 gctgagttaa acgtttatgt gataaatgga aatgcagaaa ctcattttat taatgcgact
      721 gtggatgata acagagtgtc tgaaatgact acttattcgt ctaagaaaat cgaggataga
      781 ttgattaata tagaagaaaa agtaaatggt ggtttatcta gtattgcaac aagtgtaaat
      841 gagttgataa cttattgtta aaggagagtg agaaaatgca gacagaatgg aactttgggt
      901 acaatggttc gccacaaagt gttatattga aacctggcaa atataaattt gaatgctggg
      961 gttcttctgg aggtatcaac aattcttctt ggtatactga tgctaaaggc ggatattcta
     1021 aaggtgaaat tacattaaaa aaacaaacta cattatatgt ttacgtcggc gaaagtggtt
     1081 ttgcttcttc atctacgagt aataacacta aaagtggttt taatggcggt ggtaaaggtt
     1141 atttaaatca acagattatg ggtacttatt attctatgta cggtggtggt gctaccgata
     1201 taagacttgt tggtggtgct tgggataatg agcaaggttt gctatctcgt ataattgtcg
     1261 caggtggtgg cggaggttca tattatcctt ccactggtgg tgcaggagga ggattagaag
     1321 gaggtactgg gtatagttct aatgacagat accgtcccgg tggtactcaa tatcaaggtg
     1381 gtattggtcg tgtaaataca gaaaacggaa gttttggaaa agggtgttct gttaaagatt
     1441 caactggcga aggcggcgga ggtggctggt ttggtggtgc aggcatgaat ggtgtaggag
     1501 caggtggagg tggaagtagt tatgtattga ctaaagacag ttataagcct actggctaca
     1561 caccaacatc tgaatattat tttgataata ttgttatgac accgggtgga aatactgctg
     1621 gtgcttatgg ttacgcacaa ataactttac ttcaatcatt accattttta aatatatcat
     1681 cttataattc tacacaagca acattcaaag ctgaccacac tgaccctact ttattgacta
     1741 agatagaata ttttatagat gatgtattaa aagaaactat aacaacagat ttaacagaag
     1801 aaaaaacaat taactataca ctag
//
LOCUS       DAGQVA010000173         1805 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.180, whole genome shotgun sequence.
ACCESSION   DAGQVA010000173 DAGQVA010000000
VERSION     DAGQVA010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.180"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..92)
                     /locus_tag="MIV85_003808"
     CDS             complement(<1..92)
                     /locus_tag="MIV85_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963083.1"
                     /translation="MKDKWILCPVCGNKTRLKIRADTELKNFPL"
     gene            complement(131..418)
                     /locus_tag="MIV85_003809"
     CDS             complement(131..418)
                     /locus_tag="MIV85_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963084.1"
                     /translation="MSTLIIGFIVAGVLLIAEYLLCTKFRSPLWGGIIPLLILAGTIY
                     VFASGRIPFERPYIFPFVVVNTLFFGDWGTGRDKYKKIKQTEMEKMKAKDI"
     gene            complement(421..717)
                     /locus_tag="MIV85_003810"
     CDS             complement(421..717)
                     /locus_tag="MIV85_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009460866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2089 family protein"
                     /protein_id="HBY2963085.1"
                     /translation="MELDKIPQWILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPT
                     VRLRLDKLIQKIEMCDQQEEEPFQTFIKGLAVDSRIDVETAKIIIEKYKKEKEK"
     gene            complement(806..1711)
                     /locus_tag="MIV85_003811"
     CDS             complement(806..1711)
                     /locus_tag="MIV85_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBY2963086.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKSVIALWVVLIASVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISG
                     YLTKELQALNTDTIRKDIPVSSAVNGVQIWSVTQADENQFSVIFTVEQLITENGSTKT
                     VRSAYEVTVYVDGSGNMVLTKNPTITSIPVKSGYTPKAKESDGTVDAVTTDEINEFLT
                     TFFKLYPTATAKELSYYVNEGVLKPIGKDYVFSELVNPIYNRIDSQVTVSVAVKYLDQ
                     QTKATQVSQFDLVLEKSGSNWKIIK"
BASE COUNT          485 a          397 c          300 g          623 t
ORIGIN      
        1 aatagtggga aatttttaag ctctgtgtcc gctctaattt tcaacctcgt tttattaccg
       61 caaactggac ataaaatcca tttatctttc aataatgcgt tcctcctatc taagtataca
      121 gttttgtaat ttatatatct ttagctttca tcttttccat ttcagtttgc tttatctttt
      181 tatatttatc cctgccagta ccccaatctc caaaaaataa agtattgact acaacaaacg
      241 ggaaaatata tggtctttca aatggtattc tgccacttgc aaaaacatat attgttcctg
      301 ccaagataag caagggaata atacctcccc aaagaggact tctaaatttt gtgcagagaa
      361 gatactctgc aattaataaa actcctgcaa caataaagcc aataattaat gtactcatgg
      421 ttatttctcc ttttcttttt tatatttttc aataattatc tttgcagttt ccacgtcaat
      481 tcgagaatca accgctaacc ctttaataaa agtttggaaa ggttcttctt cctgctggtc
      541 gcacatttca attttttgaa ttaatttgtc taaacgtaat cgaacagtag ggtaagatac
      601 cccatacatt ttcgctattt cctttaatga accggattta agtgcgaagt ttttaagaaa
      661 agtagcgtcc tcttgctcta aggcaagaat ccattgaggg attttatcaa gctccaaaaa
      721 cacaactcct ttcatattat ctttaacaat attcagtata tcataaataa aattaaagtc
      781 aataagaatt taaacatcaa aataattatt ttataatctt ccagttgctc ccgctttttt
      841 ccagcaccaa atcaaattgt gatacctgcg ttgcctttgt ctgctggtcg aggtacttca
      901 cagccacgga aaccgtcact tgactgtcga tgcggttgta gatgggattt accagttccg
      961 agaatacata atctttcccg ataggcttta acacgccctc atttacataa taggacagct
     1021 ctttagcggt tgcggttggg tagagcttaa agaacgtcgt cagaaattcg ttgatttcgt
     1081 ccgtcgtcac agcgtccacc gttccgtcgc tttcctttgc ctttggcgtg tagccggatt
     1141 tcacgggtat gctggtaatg gtcggattct tcgtgagaac catgtttcca gagccatcca
     1201 catagaccgt gacttcatag gcggagcgta ccgtcttcgt gcttccattc tccgtgatta
     1261 actgttccac agtgaagatc acggagaact ggttttcatc cgcctgcgtg acagaccata
     1321 tctgtacccc attgaccgcc gaagacactg gaatatcctt gcggatggta tcggtattaa
     1381 gtgcctgcaa ttcctttgtc agataaccgc tgattgcctg cgtccttgct tcaatagctt
     1441 ctttgctgtt attccatgtg taataggact tcgcaaagtt cttcacgaaa ttttcaatcc
     1501 cgttggtatc ggtaagtctt aactgtatgg tttctgtttc atgtacggtg tgcatatcaa
     1561 tagcggtaaa attcttatat accccaaaac tcacgcttgc gataagcact acccacaatg
     1621 caatcacaga ttttttatgt gtaccgactt tcacagtacg cactttcttt tctttgacat
     1681 tctctgtctg tttcttattc ttcttaaaca tattttctaa gtcctttctt ttattttact
     1741 cgtcctgcac cgattaagtg ttgttgccag taactattat ttaagtctgc atatcctatc
     1801 ggatt
//
LOCUS       DAGQVA010000174         1800 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.181, whole genome shotgun sequence.
ACCESSION   DAGQVA010000174 DAGQVA010000000
VERSION     DAGQVA010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1800
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.181"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            42..1520
                     /gene="ade"
                     /locus_tag="MIV85_003812"
     CDS             42..1520
                     /gene="ade"
                     /locus_tag="MIV85_003812"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBY2963087.1"
                     /translation="MHIESTMVMPIELSKKLLKSGTTTIIADPHELVNVKGVSAIDFL
                     LESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNNPRILGLGEVMCFNDV
                     INSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDHECITFDEVYEKLRAG
                     LKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDIEKQGHIRWNIKCAID
                     LGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLDKMEVDSVYKDGNLVN
                     EEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEIVPYQILTNKVYESLP
                     CADGYFVPNKEYSKLCVVERHRMTGNVAVAPLKGFGIKNGAIATTVAHDSHNIIVAGD
                     NDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFTAEEVQEITDNMLEIA
                     RKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT          698 a          191 c          322 g          589 t
ORIGIN      
        1 gtagcaataa atatatatca cctggcttta ttgatgcaca tatgcatatt gaatctacaa
       61 tggtaatgcc aattgaatta tcgaaaaaat tattaaaatc aggtacgaca actatcatag
      121 ccgacccaca tgagttggtc aatgtaaaag gagttagtgc aatagatttt ttattagaat
      181 cgacaaaaga tataccactt aatgtatata ttatggtgcc ttcatccgta cctgcaacaa
      241 gttttgaaac taatggagtt ggtaaattta gtgcaaaaga catggagagt tatgtaaata
      301 atcctagaat tttaggttta ggagaggtaa tgtgttttaa tgatgttata aattctgaaa
      361 atgaaatctt ggataaacta gagcttttta aaaataaagt tgtagatgga catgcaccta
      421 atataaatgg taaatcactt cagacatatg tatgtgcagg aatagaaaat gaccatgaat
      481 gtataacttt tgatgaagta tatgaaaaat tgagagcagg attaaaaatt ttaataagag
      541 aaggaagcgc agcaaaaaat ttaaagtcta tagtaagtgg tatgctaaag cataacttgc
      601 caattgaaga atttatgttt tgcacagatg ataagcactt agatgatata gaaaaacaag
      661 gtcacataag atggaatata aaatgtgcga ttgatttagg tatggaacct gttagggcta
      721 taaaagttgc aacttataat tctgcaaaag catatgggtt aaggaaaatt ggagcaatag
      781 gtgcgggtta taaggcagat attgttgtat tgaatgattt agacaaaatg gaagtggata
      841 gtgtatataa agatggtaat ttggtaaacg aagagatgtt ttctaattac aattatgaga
      901 ttaaagataa agaattgctt aatacagtca agtttaaata tattaataaa gaaaaaatac
      961 agttaaaagt aagtgaaaaa aattatgtaa tggagattgt accttatcaa attttgacaa
     1021 ataaggtata tgaatcttta ccatgtgcag atggatattt tgttccaaat aaagagtatt
     1081 caaaactttg tgttgttgag agacatagaa tgactggaaa tgtagcagtt gctccactaa
     1141 aaggatttgg cataaaaaat ggagcaattg ctactactgt ggcccatgat tctcataata
     1201 ttatagttgc aggggataat gatgatgata ttctagtagc tataaattac ttaaaggaaa
     1261 tacaaggtgg ttatgtaatt gtatcaaatg gaaaagttct tgcacaccta agtcttcaag
     1321 tagctggatt aattagtact tttacagctg aagaagtaca agaaattact gataatatgt
     1381 tggagatagc aagaaaaatg ggagttccag agtatgtaga cccttttatt acactttctt
     1441 ttatggcact tccagttgtt ccacaaataa gacttacaga tttaggtcta tttgatgttg
     1501 aggaatttaa atttatatag ataatataaa agtaataata aatgaggctt tctcaaaata
     1561 gggataagtc tctttttatt gttgaaatga taaaaatata tttgatttca tacaaaaaag
     1621 agcatctcat gaactaaaaa ttttattttt agatatcctt attttaatta atctatcatt
     1681 taaccttgtt ttaagcatag atatcttaat aaaactattt tcagtctatt ttaacatata
     1741 aatacatgaa aattatatat ttatgaaact ttatacataa aaaataaaat attttattta
//
LOCUS       DAGQVA010000175         1795 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.182, whole genome shotgun sequence.
ACCESSION   DAGQVA010000175 DAGQVA010000000
VERSION     DAGQVA010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.182"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..818
                     /locus_tag="MIV85_003813"
     CDS             <1..818
                     /locus_tag="MIV85_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBY2963088.1"
                     /translation="GNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNLI
                     AISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETKI
                     GTVNTKIDTTKTELTSNIETAKTELNTKIDQLIAGGSNVAYTQRVAIDDWVEDAESGF
                     KATVTHSLLTQRIVVNIIDATTKENIVPNFKIVDDNSIEIRSEVKVELNVYVINGNAE
                     THFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKVNGGLSNIATSVNELITYC"
     gene            835..>1795
                     /locus_tag="MIV85_003814"
     CDS             835..>1795
                     /locus_tag="MIV85_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963089.1"
                     /translation="MQTEWNFNYANYVQNVSLPPGRYKLECWGACGGAVDTSDWTDCA
                     KGGYSKGEIVFKKRTNLQICVGQSGYEKVSEGSSLTRSGFNGAGAAGKVTTGSFAYSK
                     YGGGATDIRLYHPSATWGNTESLLSRILVAGGGGGMKNNFASARSIGHGGGYVGVNGV
                     GRDRDFCGGGSQYQGGTSYDTEEYHGSLGKGGYGNIGIGGGGGWYGGAGSYSNECGGG
                     GSGYALNKDSYKVPGYIPTPEYYLENIVMTTGGNTTKADGYAKITLLQALPFLTVSSY
                     NSTQATFKADHTDPALLTKIEWFIDDVLKETITTNLTEEKTINY"
BASE COUNT          655 a          231 c          386 g          523 t
ORIGIN      
        1 aaggcaatat cggaaataca actacagatg aaactgcacc aaattgtata atattagaga
       61 gtttaatacc atcaagtgta ggcgggttta tgataagaga aataggatat ttagatgatg
      121 aaaataattt aattgccatt tctaaataca aagagtgtta taaaccttct atagaacaag
      181 gtgcagtggt agacatgaag gttaaaactg tgcttattgt atctaatgta aataatatag
      241 aacttaaaat tgacccaaca ataatctttg caacactcaa agatatacaa gacttagaaa
      301 ctaaaatagg tactgttaat actaaaattg atacaactaa aacagaatta acaagcaaca
      361 tagaaactgc taaaacagag ttaaatacta aaatcgacca attaatcgca ggtggctcaa
      421 atgttgcata cactcaaagg gtcgcaattg atgattgggt tgaggatgca gaaagtggat
      481 tcaaagcaac tgtaacacat agtttattaa cacagagaat agttgtaaat attatagatg
      541 ctactacaaa agaaaatata gttccaaatt ttaaaatagt tgatgataat tcaattgaga
      601 ttagaagtga agtaaaagtt gagttaaatg tctatgtgat aaatggaaat gcagaaactc
      661 attttataaa tgcaactgta gatgataaca gagtatctga aatgactact tattcatcta
      721 agaaaataga ggacagattg gttaatatag aagaaaaggt aaatggtggt ttatctaata
      781 ttgcaacaag tgtaaatgag ttgataactt attgttagag aggagagtga gaaaatgcag
      841 actgaatgga attttaatta tgctaattat gtacaaaatg tttcattgcc acctgggcga
      901 tataaattag aatgttgggg tgcttgtggt ggtgctgtcg atacaagcga ttggactgat
      961 tgtgcaaaag gtggttattc aaaaggtgag attgtattta aaaaaagaac taatctacaa
     1021 atttgtgtcg gtcaatccgg ttatgagaaa gtttctgaag gttcaagcct tactagaagt
     1081 ggttttaacg gtgcaggcgc tgctggcaaa gttactactg gtagctttgc ttattctaaa
     1141 tacggtggtg gagcaactga tataagactt tatcatccta gtgcaacttg gggtaacacc
     1201 gaaagtttgc tttcacgcat acttgttgca ggcggtggag gaggtatgaa aaataatttt
     1261 gcttctgctc gttctattgg tcatggtggt ggttatgtag gtgttaatgg agttggtcgt
     1321 gacagagatt tttgtggcgg tggttctcaa taccaaggtg gaacaagtta cgacacagaa
     1381 gaataccatg gttcattagg aaaaggaggt tatggtaaca taggaatagg tggtggaggg
     1441 ggttggtacg gtggtgctgg ttcttattct aatgaatgtg gaggtggtgg aagtggttac
     1501 gcactaaata aagatagtta taaggtaccc ggatatatac caacacctga atattatctt
     1561 gaaaatatag tcatgactac tggaggtaat actactaaag cagatggtta tgctaaaata
     1621 acattactac aagcattgcc atttttaaca gtatcttctt ataattctac acaggcaaca
     1681 tttaaagccg accacacaga ccctgcatta cttacaaaga tagaatggtt tatagatgat
     1741 gtactaaaag aaactataac aacaaattta acagaagaga aaacaattaa ttata
//
LOCUS       DAGQVA010000176         1654 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.183, whole genome shotgun sequence.
ACCESSION   DAGQVA010000176 DAGQVA010000000
VERSION     DAGQVA010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.183"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(12..374)
                     /locus_tag="MIV85_003815"
     CDS             complement(12..374)
                     /locus_tag="MIV85_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963090.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            941..1333
                     /locus_tag="MIV85_003816"
     CDS             941..1333
                     /locus_tag="MIV85_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2963091.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
BASE COUNT          628 a          248 c          138 g          640 t
ORIGIN      
        1 atatagagcc tttattttct agtaacatag ctattaaacc tcagtttttt aaattcattt
       61 tttatctcta tatttatttc atagcattga taataatcta aaatttgctc tattctactg
      121 ttaatttcat atccatttat gtaatttttt tctatcttat cttcaattaa ctcatactta
      181 ctattttgta ttctatactt ctcatcttct atatattttt ttgctgtact taacatttct
      241 ctgtcagata tatttctact gataaaacta taacaattat acaatgatgt agaaactaaa
      301 taaacagcca catataatat agcaatactt attatacatt caattgatat aaaaccactc
      361 tttcttattt tcaataataa aaacaacccc taaataatat tttatatata aacatttaac
      421 tataagtttt ttcgtaaata tcttttgtaa gttttttcat tgtaatcaaa atttcttccc
      481 atacatatat aaattaacac accaccttca tccttaacag tattaactat gactgatact
      541 tttgcttgta atcaacttta tacaaacaat taattacatt tactttttta agtattgtaa
      601 aattacacct cctatattca tatttttata gactctaatg ctttgcatta atcttttact
      661 tcaacaccaa aacatatata aatactattt ccttttatat ttattgacac ctcaattcca
      721 atttatactt tataaatcaa taatttcttc gccttgtttc atatatatac aacaaaaact
      781 taaatttaaa ttcccactct ttatgtcata ttccattcaa aagtttgcaa atatatgttt
      841 taaattctaa aaatatgcat attattttat tagataacag tcaacttgga taagtctcct
      901 tcatataatt taaagtgacc gttgaaaagg gggtgaccta ttggcagctc ttaaatcttt
      961 tgaaaaaccc ttaacccctg aagaagagat tgagtattta actaaattta aaatagaaaa
     1021 cgataaaagt gcaaaagata cattaattga aagaaacatg agattagtag cttatatagc
     1081 aaagaaatat aataattcaa cggaagatca ggatgattta atatccatag gtacaatagg
     1141 attaattaaa gctatagaaa cttataacat agataaagga actcgattag caacatatgc
     1201 ttctagatgt attgaaaatg agattttaat gaatattaga tctaacaaaa aaaataaaac
     1261 tcaagtatct ctacaagacc ctatcggaac agataaagaa ggtaatgaaa taaatactac
     1321 tctttatatg taattttcta ctattatata tttatttact ctataaaata atccccattc
     1381 aaaacacttt tcttaaatca ctcaaactaa aatacatata agattatcat tagtcagtaa
     1441 gtatatattt ttctaatttc taaaaataca tccaaatcat caaacgtttt tagcaattac
     1501 tttattatta tacagtgtcc aagtaaagct cctaaataaa ttgttattca tatagcaaac
     1561 aaatacttgg tatcaatttt ttaatatcta tttaaatagt attttttatt ttgtcatttt
     1621 atagatatta atgtgtattt aatactgcta aaaa
//
LOCUS       DAGQVA010000177         1615 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.184, whole genome shotgun sequence.
ACCESSION   DAGQVA010000177 DAGQVA010000000
VERSION     DAGQVA010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.184"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            197..907
                     /gene="rgaR"
                     /locus_tag="MIV85_003817"
     CDS             197..907
                     /gene="rgaR"
                     /locus_tag="MIV85_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBY2963092.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNTITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT          626 a          131 c          238 g          620 t
ORIGIN      
        1 tattttttta cataatatat ctagaaaagt ataggaattt atcgtaattt aagtttaaat
       61 attaaagaga atttctataa gtagtttaat cgacaattta aatttataaa gaaatttaaa
      121 tttgaaagct agtgagtaca gtttggaaat tgaaataaag taaactaaat gatattttag
      181 atttggaggt gatattatgt tcagggtagt tatatgtgat gacgaaaaaa tacaaagaag
      241 catactaaaa gagtttacag aaaaactttt gtctgaaaga tgtctaaatt atcaaatact
      301 ggaattttcc tgtggagaag atttaatatc caaataccca gaaaaaattg atattatatt
      361 tttagatatc caaatgaaag atatcaatgg aattgaggtg gctaaaaaaa taagaaagtt
      421 tgatgaaaaa gtagaaatta tatttacaac ggctttttca gagtatgccc cccaaggtta
      481 tgaagttcgt gcttatagat atttagtaaa gcctatagag tatagtaact ttgcaatggg
      541 tgtaaatctt tgtattgata accttcaaag aaagaaggag cgttatatag ttttaaatag
      601 taaaaaagga tttaatagaa tactgataga ttctatttta tatgttgaaa ctgtaaagag
      661 agatttagtt gtacatacaa taggtagaga ttataaagct aatatgagca tgaaacaagc
      721 agaaaaatta ctgtgtgaaa atggcttttt tagatgtcat acaagtttta ttgttaattt
      781 aagaagaata gaagatctta gggataatac gattactatt aatgaacaat ttatacctat
      841 aagtaagtat agacttaaag atttaaaagt agcattaaca agcttgttat gtgatataat
      901 gtattaattt taaaaaggta attgaaaata tcgtaaaaaa gatttaatgt catcacaggg
      961 ctattgattg aaactgtctt aatatataaa atgttattta tattaagaca gttttattat
     1021 gcaaaatagc agtttataga cttttaatat ggtttaatat gtatatgtag agtttccatt
     1081 ataatagcat gattattaat tagtagcttg attatcaata tactattatt gatttttata
     1141 tgtattatat gtatttttag aatatgatta cctttttaaa ataatgacta tttataaaac
     1201 tctatagata tttgtttcat ttagctatgc atactttaat taattatatt aatatttaat
     1261 ggagtacaat ataaatatta aagcgacatc ttatagttta ttgaacctat agtaatgaat
     1321 taataaatag tttaattcta tgaaaagatt tccttttatg caatttattt attgaaatat
     1381 gatataatat ataaaggtgt aagtattagt tgttaaaata atatttatat tagtttttat
     1441 gcatacttgg tataagtttt tcatatattg attaaaattg atgttgattt attattttta
     1501 gtattttttc accttttgat tcatactttg tagaatggtg tattttctaa aactgattat
     1561 aagacaagtt cattcaaatt agcattttta tatcatataa ataattgttc cccct
//
LOCUS       DAGQVA010000178         1579 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.185, whole genome shotgun sequence.
ACCESSION   DAGQVA010000178 DAGQVA010000000
VERSION     DAGQVA010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.185"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..500
                     /locus_tag="MIV85_003818"
     CDS             <1..500
                     /locus_tag="MIV85_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBY2963093.1"
                     /translation="TESEYFDNMRLSQDFGFNHANVVLRIGFKDGELYICNEIYAHEM
                     DTSEIIKIANSIGLEKTLFMYCDSAEPDRIKMWKSAGYKAKGVKKGPGSVKAQIDYLK
                     QLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEFMDDAMAALRYSIDNKLKNNG
                     ISFLK"
     gene            506..>1579
                     /locus_tag="MIV85_003819"
     CDS             506..>1579
                     /locus_tag="MIV85_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBY2963094.1"
                     /translation="MLNIYISETDLIKVQLKKESTINLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDITYFIERGNSFIQEFLYDEYG
                     KMTDIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEIQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGV"
BASE COUNT          657 a          168 c          295 g          459 t
ORIGIN      
        1 ctacagaatc tgagtatttt gacaatatga ggttatcaca agactttgga tttaaccatg
       61 caaatgtagt acttagaatt ggctttaagg atggagagtt atatatatgt aacgaaatat
      121 atgcacatga aatggatacc tcagaaatca taaagattgc aaatagtata ggtttagaaa
      181 agactctatt tatgtactgt gatagtgctg aaccagatag aattaagatg tggaagagtg
      241 caggatataa agctaaagga gttaaaaaag gaccaggaag tgttaaagct caaatagatt
      301 atttgaaaca attaagaata catgtacatc ctagttgcac taataccata aaagaaatac
      361 aacaatggaa atggaaacaa gatgaaagaa ctggattata tcttgatgaa ccagttgagt
      421 ttatggatga tgcaatggct gcgcttagat attctataga taataagctt aaaaataatg
      481 gaataagctt cttaaagtaa aggaggtgtt aaatatttat ataagtgaaa cagatttaat
      541 aaaagttcag ttaaaaaaag agagcaccat taacctagta aaagtcatag aacactacat
      601 cttaaagcat agaccagaaa aatataaaca aggagaagaa tactattatg gtaatactga
      661 tgtaaacaat aagagaagat attatctctt agatggagct aaggttgatg attttactaa
      721 agttaataat aaagcaatta acaactacca taagctttta gttgaccaaa aggtaggcta
      781 tagtgtcgga aatcccatag tatttaatgc agatgatgat aatctcacta agcttttaaa
      841 tgacttacta ggagaagagt ttgacgatac aataacagaa ctatatctca atgctagtaa
      901 taaaggggtt gaatggttac atccatatat taatagaaaa ggtgagttta aatatgtaat
      961 aattccagct gaagaagcaa ttcctatttg ggatagtaaa agacagaggg aattagttgc
     1021 atttattagg ttttattata ttgaagatat agatggaaat aaaataaaaa gagttgagta
     1081 ctacacagaa aatgacataa cttactttat tgaaagaggt aatagtttta ttcaagaatt
     1141 tttatatgat gaatatggaa aaatgactga tatacaagaa ggtcatttta gaataaataa
     1201 caaagaacag ggatggggta aagttccatt tatacctttt aaaaataatg aaaagtgtgt
     1261 ctcagattta actttctata aatcattaat agatatatat gacaataata tttctacact
     1321 agcagataac ttagatgaaa tacaagaggt tatttatgta ttaaaagaat atccaggaac
     1381 aagtctacaa gagtttatag ataatataag atactataaa tcaattaaag tagatggtgg
     1441 aggtggagtt gataaactag agataaatat accagttgaa gctaaaaagg agcttcttga
     1501 tagattggaa aagaatataa ttatctttgg tcaaggagtt aatccagaat ctcaaaacac
     1561 aggtgacaaa tcgggtgta
//
LOCUS       DAGQVA010000179         1464 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.186, whole genome shotgun sequence.
ACCESSION   DAGQVA010000179 DAGQVA010000000
VERSION     DAGQVA010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.186"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..1257
                     /locus_tag="MIV85_003820"
     CDS             <1..1257
                     /locus_tag="MIV85_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBY2963095.1"
                     /translation="IGGAAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDI
                     KDIKEVAVVNGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYV
                     IGGTNSVSRAVEKSLPNAERLSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQ
                     LIDSLAVGVLAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKS
                     LQEKTVFEAKTVEELTDMINIASPNDIINFKPNENTVNEAFRMVTNKPITVNIKGDCS
                     KTLTVDMPNGEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDI
                     DTLMILASANDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKA
                     IDSISQKVNKIQDILDKFGFLKKFLS"
BASE COUNT          604 a          129 c          291 g          440 t
ORIGIN      
        1 ataggaggtg ctgctgtact taataaagat atagagaaca agttaaaagg taatggactt
       61 aatgtagaaa gaattaatgg taaggataga tatgaaactt cactgatttt ggctaataag
      121 cttaaggata taaaagatat taaggaagtt gctgtagtaa atggtgaaaa aggattgagt
      181 gatgctgtta gtgttggagc accagcagct caaaataaga tgcctataat tttgtctagt
      241 cctaaagatg gagtagaagc atttgataaa tttataagag atgagaaagt tataaaagca
      301 tatgtaattg gaggtacaaa ttctgtttca agagctgtag aaaagagtct tcctaatgca
      361 gaaagattga gtgggaaaga tagaaatgag actaatgcta aggtcataga aaagttttat
      421 actgatacaa acttaagtaa tttatatgta actaaggatg gtagtaaaaa tgagaatcaa
      481 ctaatagact cgttagctgt tggagtattg gctgcaaaaa atgagtctcc tgttgttttg
      541 gttggtaata aattaaacac aaaacaaaga gatatactta gtactaaaaa attaaatact
      601 ataacgcagg taggtggaaa tggaaatgaa gaagcttttg atgaaattaa aagcctacaa
      661 gaaaaaactg tgtttgaagc aaaaactgtt gaagaattaa ctgatatgat aaatatagca
      721 agtcctaatg atattataaa ttttaaacca aatgagaata ctgtaaatga agcttttaga
      781 atggtaacaa ataaaccaat aactgtgaat ataaagggtg attgttcaaa gactcttaca
      841 gtagatatgc ctaatgggga agtgaataac tatgctactt tggtaaatgt tatagttaga
      901 aatattggag aaggtggatt taataaccat gatacaatca ctatattgtc agttcgtgac
      961 aaaaatggta gagttataga aaatactaga aattcagata tagatacgtt gatgatatta
     1021 gcttctgcta atgatacaaa attgattaat gatggatata taggaaaact tatagataat
     1081 tcatctaata gtgatataac taataatggt actatagata aaaaagttaa tcaggttgag
     1141 gatttagagg ctaaggttga ttcaattgaa aaagctatag attctataag tcagaaagtc
     1201 aataaaatac aagatatact agataagttt ggatttctaa agaaatttct tagttaagaa
     1261 tatgtatatt taagtgaagt gtgtgttgta attgttctaa agttatatag ttaaacaggt
     1321 ttatatacaa acagacttat agataaatat gtagttcaat atatatttga ataagctttg
     1381 gggaggtaac atggggattg gaattgaatg taacaaaaaa ataaataaaa gtattgacaa
     1441 aactagaata aagaaaaata atct
//
LOCUS       DAGQVA010000180         1403 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.187, whole genome shotgun sequence.
ACCESSION   DAGQVA010000180 DAGQVA010000000
VERSION     DAGQVA010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1403
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.187"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            257..1369
                     /locus_tag="MIV85_003821"
     CDS             257..1369
                     /locus_tag="MIV85_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBY2963096.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
BASE COUNT          607 a          145 c          176 g          475 t
ORIGIN      
        1 ctcatccaaa tttattaata caaaaaattt atatttttat tcaaaattaa acacacaatc
       61 tattaatata aagataaata tctattctat aagtataaca gattatcaaa ttaaaattct
      121 aatatttgac ataatatata cattttttaa ataaatatat acaatgtatt aaaatgtatg
      181 caactctatt tcaaaattat tttgtgatat atatatgtta taataaatgt ataaaatttt
      241 gattggtggg ttatatatga atgcatttat tagaaaaaga aataaaaact atgttgttta
      301 cctggaattt gaagatgaaa agacaggtaa aagaaaacaa aaaaatatgg gtacttttga
      361 taaaaaaagg gaagcaagta aaagactaaa tgaggtaaaa gaaagcttat ataatgatgg
      421 ttttttagta ccaagcgaaa ttacagtgtc agaatttcta ttagattttc taaataaata
      481 tagtgaaaat atatctttag ctacatataa taattatgtt agtatttgta agaattacat
      541 taatccatct attggaaaat ataaaataca agacttacat ccggttcaca tacaaaacta
      601 catagataaa ctatcttata aactaaatcc tcaatcaatt aagattcata taaatatatt
      661 gaaacttgca ataaaaagag cttatagact caaattaata aaagaaaatg ttatggatag
      721 tatagaggct ccaagatata aaaaatttaa aaatgagatt tatgatagag aacaaatgat
      781 aaaattatta gatttagcaa aaaatacaga aatggaatta cctattaatt tggctattgg
      841 attaggtctt agaatttcag aagttttagg tctaacttgg gataatattg attttgaaga
      901 aaatacaata acagtaaata agataacttc ccgaattaat ggttctgtta ttctcaaaga
      961 gccaaagaca gaaagctctg ttagaaaaat atcttctccc aaagaattaa tgtctttatt
     1021 aaaagaatat aaaataaaac agaataaaaa tttattaaaa tcttccatta gaaataataa
     1081 taatttgttg tttttcaata agaaatgtga acctattgct gaagatgtta tgagtaaaaa
     1141 atttaaaaga tttttagaaa agaatgaatt acctcatatt agattccatg atttaagaca
     1201 ctcacatgtt actttactta taaattctaa agtacctata aaggttatat ccgagagagt
     1261 aggacactca aatataagta ctactctaag cgtttattct catgtactta aagaaatgga
     1321 taaagaggct tctgacaaaa tttctgaaag tttatttaat gctaattaat attaatttat
     1381 cttagcttta aattagctta gct
//
LOCUS       DAGQVA010000181         1373 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.188, whole genome shotgun sequence.
ACCESSION   DAGQVA010000181 DAGQVA010000000
VERSION     DAGQVA010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.188"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            288..937
                     /locus_tag="MIV85_003822"
                     /pseudo
     CDS             288..937
                     /locus_tag="MIV85_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
BASE COUNT          559 a          183 c          146 g          485 t
ORIGIN      
        1 tcataaaaat caaattcatt aaaaaatcca tttttattta caatcttata tccctttgca
       61 tctctttcta aatactcttc ctaaatactc ttcaaaactt tcatcatcta atctaaatcc
      121 tatatcacta tgaaaaatag gttttgcatt tggatatagt tctattgttt tatcaaaagt
      181 ttcgaatacc aagttattat tattcgattt tccaacagtc cactataaac aataataagt
      241 ttgttgctcc aaataatgta acacttgtag aaagatgtta cagatatata aaagatagag
      301 aatgtagttt ttctcctaat actattagaa atagaaaaaa tatgattaaa aatcaaattg
      361 aagttttctt taaagatatg aaattaatag atataactcc ttctatttta cagtcttata
      421 taaataacat atacaatgag cacatgttaa attcaacaaa aaaccaagtc gattttataa
      481 aatcagtatt gaaagaatct tatagattaa aagaaatatc agaaaatatt tgtgattttg
      541 ttacaacccc aatcaaaaaa aatagttcaa cttctaagct ttatacaaaa caaaaagctc
      601 aattattatt agaaaaatca aaaaatattc ctataggtat accaattttt ttgatgctaa
      661 ctcttggatt acgttttggt gaagctgtat cacttatatg gtcagatgta gaccttgata
      721 aaaaatctca catgtaaatc aaacattagt ttatgtatac aataaaataa tcttcaaagg
      781 ccctaaaacc cctagattca aaagaagatt atttgttcct gatgaactta taagtttgtt
      841 taaaggggaa aaattaaaac aaaataagtt aaaattacag ggtatattga aaaatgaatt
      901 tgatttgata tgcttaaata aaagattcaa cccgtgagtt caaccaactt ttgttgttca
      961 ttttaaaaaa ctattaagag ataataatcc tagagatata aaagtacatg aattaataca
     1021 tgcaaatgcg actttgatat tactttcagg tactaacata aaagctattt ataaaatatt
     1081 agtacatgca gatataaaaa tagctatgaa tatatattcc atattctcac ttattagatg
     1141 aaatgaataa agaaacatct gaaaatataa gcaaaatact attcaaataa tgttcagttt
     1201 tatgtcaatt aaatgtcact caaagtgctt tttttccatt tgtcagttaa atgtcactta
     1261 aagtaccttt ttcctatttg tcagttaaat gtcagtaata tataaataag atatatttat
     1321 aagaccctta aaatcactat tatttaataa aatttataat tatatactat ttg
//
LOCUS       DAGQVA010000182         1372 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.189, whole genome shotgun sequence.
ACCESSION   DAGQVA010000182 DAGQVA010000000
VERSION     DAGQVA010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.189"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            174..512
                     /locus_tag="MIV85_003823"
     CDS             174..512
                     /locus_tag="MIV85_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2963097.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            534..851
                     /locus_tag="MIV85_003824"
     CDS             534..851
                     /locus_tag="MIV85_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2963098.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1001..>1372
                     /locus_tag="MIV85_003825"
     CDS             1001..>1372
                     /locus_tag="MIV85_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963099.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNY"
BASE COUNT          602 a          133 c          205 g          432 t
ORIGIN      
        1 ttaaaaatat gatttatcca tatttgttta ttgtagatac agactataca aaaataaata
       61 gcacttattt cagtataaaa acatatatag tctatattta gactaaaaaa gtataaatag
      121 tctatataaa acaacttaaa ctatgaatat aatctaaagt ggagggataa taattggcaa
      181 atataggaaa aataatagga gatagaataa aagtctatag aacaaaattg ggatatagtc
      241 aagagtttct agcagaaaag gcaggtttac atccaacata tattggtcag attgaaagag
      301 ctgagacaaa tacatctatc aatattataa tgaaaattgc tactgcttta gacataccac
      361 ttgaattgtt atttgcaaat attattacaa cagaaggcgt tgataactct gtacctttag
      421 aatgttatga aatgattaat aaattaactg aaaaagaaca aattgcaatg ctagagttaa
      481 taaagtgcat cattaaatac aaagaaatat aagtgaggga aatagtaaca ataatgaatt
      541 atataggtaa aagacttaaa gaagaacgga aaaaagcaaa tttaacttca aaagaatttg
      601 caaatatggt tggagtatcg ccttggtata taactcaaat cgaaagtggt aaaaagaatc
      661 caagtcttaa aacattcata aaatttgtaa atatattaaa tatttctgca gatgttctta
      721 taaaagatat tacttccact ggaaaaacat atttagaaaa tgatataaat gaagagttaa
      781 aagacttaaa ttcaagagaa ctaaatctga tatcacagat tatagacatc ataaaaaaga
      841 ataaaatata attctttata ttttatataa aaaaaaaggt tatttgaaat aaataacctt
      901 tttttgtctt tttgtgttaa cattgtctta tagtgctaat gagtactatt agaccatgtt
      961 ctatggcctt attttaatat aaaacgattg gagataggct atgattgtga ttgaaggtag
     1021 cgataaattt aagattgcaa aagaatatat tgatgtagaa tatactcttt ttagcaaagt
     1081 aacttttagg tatgaaaagt tgaaatttaa agataatgct gaattggaaa aaattaagat
     1141 gtttaaatat aaaaatggct acatccctaa taaattaaac ctttcttttg gatatggatt
     1201 ctcttcttat aaaaagcaaa taattagaga aactgtagat actttaagat tgacagaaat
     1261 tttttcaagc gagaacatag aagatattaa atttataaaa gatggtacaa aaaaattaga
     1321 aattagcata gagaaagttg tgaaatttaa acgtcgaaaa aaaagaaatt at
//
LOCUS       DAGQVA010000183         1357 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.190, whole genome shotgun sequence.
ACCESSION   DAGQVA010000183 DAGQVA010000000
VERSION     DAGQVA010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.190"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..780
                     /locus_tag="MIV85_003826"
     CDS             <1..780
                     /locus_tag="MIV85_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2963100.1"
                     /translation="IFKDKIIDSKESLIILTISTVFLLSNLSLVSIIGRIIKDNSLKI
                     EYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNHIICIQNVYGKNEFADKYIKDIN
                     KQIKECNTIFNTQNMILDVILSDKKSICDMNNIYFLVDINFLECNFIEMPDICSIFSN
                     IIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKCENTKIDEVVLKNNKVITSKKDS
                     FLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYIPLTRN"
BASE COUNT          600 a           93 c          196 g          468 t
ORIGIN      
        1 atttttaaag ataagattat cgattctaaa gagagtttaa taatacttac aatatcaact
       61 gtatttttac tatcaaatct ttcattagta agcataatag gaagaataat aaaagataat
      121 agtttaaaga tagaatatga aattacaaaa aaaagaatga atatgcaata taaatattat
      181 ttaaatttac aggaatatca gttgaaaata agaaaactat atcatgatat gaataatcat
      241 atcatttgta ttcagaatgt ttatgggaaa aatgagtttg cagataagta tattaaagat
      301 ataaataagc aaataaaaga atgtaatact atatttaata ctcagaatat gattctagat
      361 gttattttaa gtgataaaaa atctatttgt gatatgaata atatatattt tctagtagat
      421 attaattttt tagaatgtaa ttttatagag atgccagata tatgtagtat attttcaaat
      481 ataatagata atgcaataga agcttgtatt aagattaagg acacaagtat acaaaaaaag
      541 attaaattaa gaggaactgt tataaatagg ttatttgtaa taaaatgtga aaatacaaag
      601 atagatgaag ttgtattaaa aaataataag gttattacaa gtaagaaaga ttccttttta
      661 catggaatag gaataagtag tgtaaaaagt tcagtagaaa aatataatgg aaatgtggaa
      721 atatactcag ataaaaacaa gtttacaatt actatttata taccattaac taggaactaa
      781 ttctagttgg ggctctaaat ttcccagttg gagcagtagt attgaaagat aaaatagaag
      841 atgctatctt taaggcatag gatatttgga ggtgataaaa atggttgaat gctatgctaa
      901 taagataaca tcctttttag tactcaataa aataatagaa caaaaaatgt gatttatatt
      961 tgtttgaatt taaaatgttg ataggtttta tagttatatt atttgcatga tatatcttaa
     1021 ataaatttag aaaaatagag ttatttttat ctgcaaatgc gaccttagta tggtaacatt
     1081 attgaccaaa agttctatat agtataaaaa aataaaatgt aaatttgata aactttataa
     1141 ctaggaacat aaaaacaaca attaaataac taattagata gtaaagttga tattagtaat
     1201 aaatattaaa gaaaaatatt ttactaattt gaggaggact tagttgtgat agattctgaa
     1261 gaaatgattt ttaatgtaga agatttaatt atttatagaa aaaatcaact agtaattatt
     1321 tataataaga aatttagaaa atatattaaa ttgtctg
//
LOCUS       DAGQVA010000184         1345 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.191, whole genome shotgun sequence.
ACCESSION   DAGQVA010000184 DAGQVA010000000
VERSION     DAGQVA010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1345
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.191"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(309..1055)
                     /gene="cdtR"
                     /locus_tag="MIV85_003827"
     CDS             complement(309..1055)
                     /gene="cdtR"
                     /locus_tag="MIV85_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBY2963101.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT          513 a          150 c          133 g          549 t
ORIGIN      
        1 tatataaatt tcataaaata tgtaggtata tatcataaaa atatgtattt atatgatatg
       61 tcagtacaaa ataacaactg aatattttaa agagactatt tcgtactttt atgatttaat
      121 gagctatctt atcgaatcat aatctaggaa caattgttat aatatctaat agtagttata
      181 tatgatatag tcagtatgtg ttttttcaca atatgattat tatatagagg attcttaggg
      241 attactcttt ttgtataaaa aagagatggt tcaaattttt atcttgagac atctcctttt
      301 tctatttatt atgttttaat aatattcttt aaaatatttc tatatgtatt agatatacga
      361 catatatggc cattactcat tttaatatta tttttcttta ggtcgagaga aacaatatga
      421 tatttattaa ctacaaaaga tttatgtaca cggataaagc atgcatctaa atctggtaaa
      481 gactttaaac ttttatagaa ttcaaatatt ctagaagtag tcactaattt tattttatgt
      541 ggaatagtgc ttgtttcaaa atatataact tcatcaaatg aaattttcca tagtgagaaa
      601 tctgaataga tagtaaaaaa attagagcga taattttttt ctttaatgta tcttttgtga
      661 gcaattttaa tacaagcttt tattttactt tcagcaattt ccatatcatg ttttagtata
      721 aagtccataa cttctaacct ataatcgaag atccctaaaa tcatttctat atgatttgta
      781 agaaatatga ttggactaat ataatctgat tctctaattt tttgtgctat ccataatcca
      841 tcacataatt cattacttat cttatatttt gcgtctacaa ctataaaata tattcttact
      901 ttattttttt cagtaagctc ttttaataac aaatttgcat tatgatataa tcttacaaca
      961 tcattatcaa aaccttcttt tattaaaata ttatttattt tttcttttag tttcattcca
     1021 aaacaaacat cattatcaaa gattaatata tccactaaat accctcctat aaaaaattca
     1081 aaagtaaaaa aacaaaagta ttttatagaa aatacataaa ataacactag gagataaata
     1141 agattaagga tagttagaat taaggtatat ttatgcttgt ttatatagta tatcttatac
     1201 ttatagttta caataataaa gtaaattaaa tcaatatatt attataaaaa atttatttat
     1261 attaaataat atgttttata ttaacttaga taataaaaat tttctggaat ttttattctt
     1321 atacgtgata aaaatagtta taact
//
LOCUS       DAGQVA010000185         1344 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.192, whole genome shotgun sequence.
ACCESSION   DAGQVA010000185 DAGQVA010000000
VERSION     DAGQVA010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1344
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.192"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     regulatory      642..735
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            818..1303
                     /locus_tag="MIV85_003828"
     CDS             818..1303
                     /locus_tag="MIV85_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBY2963102.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          598 a          103 c          210 g          433 t
ORIGIN      
        1 gaaatagaaa aaacatatgg ttggaagcat acaactacaa ttatactttt agctagatta
       61 accaaaaaag gttttttaat atcatagaga attgggaggc atgtacacta tacagtatta
      121 ataaaagaga gagaatatct caaaatagag ggaaaaagag tttttagagg tttacataac
      181 aatcctttat cagaattaat ttcaaaatta catgatggag aagaaataac tgaagaaaaa
      241 ataatagaaa taggaagttg gataaaaagc tggaaatata aagattaata aataaaaggt
      301 agctaataat ataagtgcta ccttttttat gtggataata ttggtgataa gttgtggaaa
      361 acttatataa aaattgtgga taaagtgttt tgctgacatt ttactgacaa aagttaaaaa
      421 aataaatgtt atatattgta aaatgttgaa aaatagccat atatataaaa tataagtaac
      481 actatagata aattactgtc ttttatattg actataaaga acagtaattg aataaatata
      541 aagatatttt ttgattatta ttaattaaaa atttaattta tatttaaata atataaaatt
      601 tgaggtaata ttatttttta attgttcaaa ttatgttatt attcagatat aggcaatatt
      661 agataaatct aatgacgcaa aactataggg actaaaatct ttatgtaata aaggtcatgt
      721 cagccagttg ccaaaaagat aataattctt tttgttaaaa gtatttttag agttatatat
      781 tttaataact taatatttgg caagaggagg gcttaagatg atatctgaat taatgttaaa
      841 aaattttcgc aaatctagca tcaattttaa gactaaaatt aaattgaatt taagagaaaa
      901 accagacata aatagtttga aattaaaaag tataccagaa ggtaaaattg ttaagttaaa
      961 gtgtgtagat ggaatatggg cagaagttga gagtaattat gacaaaggtt ggttacttta
     1021 taaatattta gaaagattaa gtaatgctaa aaacaatagt aatgatacaa taaaaaatag
     1081 aaaaaagaat tacataggaa atataagaac aaatggatta agtttagaac ttagaaatga
     1141 tagaacatta gaatctaaag ttataactac aatccctgat ggttttaaag ttgaagtatg
     1201 ttatagcgtt ggaaaatggg caagagttaa tatcaataaa aatgaaaaac gatattctgg
     1261 atatgtatat aatcaataca tagaagagca tttaagttta taatacgata ctagcaagct
     1321 ttaaatatat taataaatcg caaa
//
LOCUS       DAGQVA010000186         1260 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.193, whole genome shotgun sequence.
ACCESSION   DAGQVA010000186 DAGQVA010000000
VERSION     DAGQVA010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1260
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.193"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            1..75
                     /locus_tag="MIV85_003829"
     tRNA            1..75
                     /locus_tag="MIV85_003829"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33..35,aa:Thr,seq:tgt)
     gene            90..174
                     /locus_tag="MIV85_003830"
     tRNA            90..174
                     /locus_tag="MIV85_003830"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:124..126,aa:Tyr,seq:gta)
     gene            184..267
                     /locus_tag="MIV85_003831"
     tRNA            184..267
                     /locus_tag="MIV85_003831"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:218..220,aa:Leu,seq:tag)
     gene            297..373
                     /locus_tag="MIV85_003832"
     tRNA            297..373
                     /locus_tag="MIV85_003832"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:331..333,aa:Arg,seq:tct)
     gene            381..456
                     /locus_tag="MIV85_003833"
     tRNA            381..456
                     /locus_tag="MIV85_003833"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:414..416,aa:Gln,seq:ttg)
     gene            546..634
                     /locus_tag="MIV85_003834"
     tRNA            546..634
                     /locus_tag="MIV85_003834"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ser,seq:tga)
     gene            638..713
                     /locus_tag="MIV85_003835"
     tRNA            638..713
                     /locus_tag="MIV85_003835"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:671..673,aa:Phe,seq:gaa)
     gene            720..793
                     /locus_tag="MIV85_003836"
     tRNA            720..793
                     /locus_tag="MIV85_003836"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:754..756,aa:Met,seq:cat)
     gene            808..884
                     /locus_tag="MIV85_003837"
     tRNA            808..884
                     /locus_tag="MIV85_003837"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:842..844,aa:Ile,seq:cat)
     gene            914..990
                     /locus_tag="MIV85_003838"
     tRNA            914..990
                     /locus_tag="MIV85_003838"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:948..950,aa:Pro,seq:tgg)
     gene            998..1074
                     /locus_tag="MIV85_003839"
     tRNA            998..1074
                     /locus_tag="MIV85_003839"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1032..1034,aa:His,seq:gtg)
     gene            1083..1158
                     /locus_tag="MIV85_003840"
     tRNA            1083..1158
                     /locus_tag="MIV85_003840"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1116..1118,aa:Lys,seq:ttt)
     gene            1166..1239
                     /locus_tag="MIV85_003841"
     tRNA            1166..1239
                     /locus_tag="MIV85_003841"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1198..1200,aa:Cys,seq:gca)
BASE COUNT          307 a          283 c          331 g          339 t
ORIGIN      
        1 gctggtgtgg ctcaacggta gagcagctga cttgtaatca gcaggttgta ggttcgattc
       61 ctatcaccag ctccatgtaa aattaatacg gaggatttcc cgagcggcca aagggggcag
      121 actgtaaatc tgttgtcatc gacttcggtg gttcgaatcc accatcctcc accaaaaaaa
      181 tgcgcggatg tggcggaatt ggcagacgca ctagacttag gatctagcgc cattggcgtg
      241 ggggttcgac tcccttcatc cgcaccattt ttgtttgata tacatatata tattgtgggt
      301 gcatagctca gctggataga gcaacgccct tctaaggcgt gtgtccgggg ttcgaatccc
      361 tgtgcgctca ccacatatat tggggattag ccaagtcggt aaggcacatg actttgactc
      421 atgtatgcgt aggttcgagt cctgcatccc cagccaaatg atgtacttac taagctatat
      481 ttgaattatt tttattttaa atatagttag gttcaatttt agaataagtt taagtatccg
      541 aatgtggaga ggtgtccgag tggtttaagg agctggtctt gaaaaccagt gacttcgaaa
      601 ggggccgtgg gttcgaatcc caccctctcc gccaaatgcc cagatagctc agtcggtaga
      661 gcaggggact gaaaatcccc gtgtcggtgg ttcgattccg cctctgggca ccaaaatatg
      721 gcggtatagc ttagttggct agagcgttcg gttcataccc gaaaggtcat aggttcgact
      781 cctattaccg ctactaaaat ttaatgtggg ccattagctc agttggttag agcgcccggc
      841 tcataaccgg taggtctggg gttcgagtcc ctgatggccc accacattaa attaattaat
      901 ataaatataa attcgaggtg tagcgcagtt tggtagcgca catggtttgg gaccatgggg
      961 ccgggggttc gagtcccttc acctcgacca atataaggtg ggtatagctc agttggttag
     1021 agcgccagat tgtggctctg gaggtcgtga gttcgactct cattatccac cccaaattat
     1081 atggtctatt agctcagtcg gtagagcacc tgacttttaa tcagggtgtc ccgcgttcga
     1141 gtcgcggata gatcaccaaa aaggtggcga catagccaag tggtaaggca gtggactgca
     1201 actccttgat ccccagttcg aatctgggtg tcgcctccaa aatattccaa ggtagctcaa
//
LOCUS       DAGQVA010000187         1185 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.194, whole genome shotgun sequence.
ACCESSION   DAGQVA010000187 DAGQVA010000000
VERSION     DAGQVA010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.194"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            104..595
                     /locus_tag="MIV85_003842"
     CDS             104..595
                     /locus_tag="MIV85_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963103.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            623..>1185
                     /locus_tag="MIV85_003843"
     CDS             623..>1185
                     /locus_tag="MIV85_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963104.1"
                     /translation="MRITKTTFNDVFSSDANESIIKVEKYVDKKCASVFEILTYTIIV
                     TNTNRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMK"
BASE COUNT          530 a           99 c          163 g          393 t
ORIGIN      
        1 ttaaaagtaa ataacaacta gatagtgaat aataaaaaat ggtaatttga aataattttt
       61 atgaatagta ttaatatata gatacaggga gattgatgcg attatgtatg aaaataataa
      121 ggtaatatac aaccttgaaa gatgtgaaaa actagaaaag actctttatt tatctcaatt
      181 taatacatat aaaaatttta aattagcttc taaaaaaact gtaataaatt cattagagac
      241 atatgtttac aatatgaata ttaacaatat aagtcttgtt gatactatag aatgtatatc
      301 attagaagat gaacaactta caggaaagaa gttgatttta gttggtgata tagatattga
      361 tgcaatatta gattatgcag gaaataaaag aaatagaaat tctagtaaaa aaaatacatt
      421 taaattaaaa atacccttta gtacatttat acaaatgcct agaaagatag aaaataaaga
      481 taaaattaat ttaaagtatc ttatacaaga tattacttca tctattttag atgataattt
      541 atttattagt gttactgcaa ttataagtta tgaaaatagt tccaagatag agtaatcttt
      601 aaattataga aaggtggatg caatgagaat aacgaaaact acttttaatg atgtattttc
      661 aagtgatgca aatgaaagta ttataaaagt agaaaaatat gttgataaaa aatgtgcatc
      721 tgtatttgag attttgacct acactattat tgttacaaat acaaataggt acaaaactgg
      781 aaatatattt ttcaaagatt atatttctaa atatatagag tttataaata atactgtaaa
      841 agttaatggc attataaaac gtggattaga cccacagcaa ggtttttaca tagggagaat
      901 agatgcaagt tgtaaaaaaa taatatcttt taagagtgta gttttaccaa attctgcaca
      961 taggattata aagaatagtg ctaatatata ctattattat aagtgtaatc tagataaatt
     1021 cccaacaaga atatcaatag aaagtaatag agtttatact aatgtaaata aaattgtatt
     1081 caaacaattg aatataagta atactttaaa agctcctaaa aatctaagag atatattaaa
     1141 agtaaatgta aatagtaaaa tatttgatgt taaacctatg aaaaa
//
LOCUS       DAGQVA010000188         1165 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.195, whole genome shotgun sequence.
ACCESSION   DAGQVA010000188 DAGQVA010000000
VERSION     DAGQVA010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.195"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(7..189)
                     /locus_tag="MIV85_003844"
     CDS             complement(7..189)
                     /locus_tag="MIV85_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963105.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFELDDVTNAEYRKAVED
                     YIIRESGVVEEAEPTI"
     gene            complement(189..482)
                     /locus_tag="MIV85_003845"
     CDS             complement(189..482)
                     /locus_tag="MIV85_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963106.1"
                     /translation="MDRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGS
                     IDYTRNRIIGINIETKEPILEEIPVFISEEEKRIQELENQILLNENKKVGGIL"
     gene            complement(499..>1165)
                     /locus_tag="MIV85_003846"
     CDS             complement(499..>1165)
                     /locus_tag="MIV85_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963107.1"
                     /translation="VSISKNIMPLPENVNLNDISTKLVEVNAGFKTGKTSIINTLALK
                     NIEASLNNTLVELSEKIKTSFDSSDASVQDLMNQLTQANNTISQLNSKYKVASGNSVV
                     NYCTNTKGFYFNSDYLFLFPGAIQINGLNFVPNIFFTTFELIDDGYFHKYFVFACRGI
                     FTQDFVITAHYYRLTSYLQDFKVGGEVLKLNERDVYMDNRGIQLPCSRQGSSFKWQAI
                     KFI"
BASE COUNT          366 a          209 c          125 g          465 t
ORIGIN      
        1 aaccctctat atagttggtt ctgcttcttc gactactcca ctttctctaa ttatataatc
       61 ctctactgct tttctgtatt ctgcattagt tacatcatcc agttcaaatt ctcgattttt
      121 taaagggttt aagcctccgt ttaatattct ctctgctaat attcttacca caacattatt
      181 tatattcatt ataaaattcc tcctactttc ttattttcat ttaataaaat ttgattttct
      241 aactcttgta ttcttttttc ttcctccgag ataaatactg gtatttcttc taaaattggt
      301 tcttttgttt ctatatttat acctataatt ctatttcttg tatagtctat acttccatac
      361 tcaacatcaa tataatgtaa ttctgttatt gtatcatgtt ctagtatatc tcctgttgct
      421 tcccctgtct gtagcagtat tttgcctgtc tggtcgtaaa ttattctatt tgctctatcc
      481 attttatcac ctcatttatt aaataaattt tatagcttgc catttaaaag aagaaccttg
      541 tcttgaacaa ggaagttgta tacctctatt atccatataa acatcacgtt catttaattt
      601 aagaacctca cctccaactt taaaatcttg taaatatgat gttagacgat aataatgagc
      661 agtaattaca aaatcttgag tgaaaatacc acgacaagca aaaacaaaat atttatgaaa
      721 ataaccatca tcaattaatt caaaagtagt aaaaaatata ttaggaacaa aattaagtcc
      781 gttaatttga atggctccag gaaataggaa cagatagtca ctattaaaat aaaatccttt
      841 tgtattagta caataattaa caacactatt gccactagca actttatatt tagaatttaa
      901 ctgacttata gtgttattag cttgtgttaa ctggttcatc aaatcctgta cactagcgtc
      961 tgaactatca aaacttgttt ttattttctc tgacaactcg actaatgtgt tatttaaact
     1021 tgcttctata ttctttagtg ccaaagtgtt tataatactt gttttaccag tcttaaatcc
     1081 tgcattaact tcaactagtt tagtagatat atcatttaaa ttaacatttt cgggcaatgg
     1141 cattatattc ttacttatac tgaca
//
LOCUS       DAGQVA010000189         1133 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.196, whole genome shotgun sequence.
ACCESSION   DAGQVA010000189 DAGQVA010000000
VERSION     DAGQVA010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.196"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..>1133
                     /locus_tag="MIV85_003847"
     rRNA            <1..>1133
                     /locus_tag="MIV85_003847"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          299 a          250 c          342 g          242 t
ORIGIN      
        1 ggatgtgatg gggagcgaaa tttagtagcg aagtagctga tttcacactg tcaagaaaag
       61 tctctatcga ggttaaaggt acccgtaccg caaaccgaca caggtgggtg aggagagtat
      121 cctaaggcca gcgagagaac tgttgttaag gaactcggca aaatgacccc gtaacttagg
      181 gataaggggt gccaccatca ggtggccgca gagaataggc ccaagcgact gtttaccaaa
      241 aacataggtt tctgctaagt cgcaagacga tgtataggag ctgacgcctg cccggtgctg
      301 gaaggttaag gggatctgtt agagcaatcg aagcagtgaa cttaagcccc agtaaacggc
      361 ggccgtaact ataacggtcc taaggtagcg aaattccttg tcgggtaagt tccgacccgc
      421 acgaaaggcg taacgatttg ggcactgtct caacaacaga ctcggtgaaa ttgtaattcc
      481 ggtgaagatg ccggatacct gcgacaggac ggaaagaccc catggagctt tactgtagct
      541 tgacattggg tcttggtact acatgtacag gataggtggg aggctttgaa accaggacgc
      601 cagttttggc ggagccatcc ttgggatacc acccttgtag tactgggact ctaaccatag
      661 gccatgaatc tggtcttggg acactgtcag gtgggcagtt tgactggggc ggtcgcctcc
      721 caaaaggtaa cggaggcgct caaaggttct ctcagtacgg tcggaaatcg tacgtagagt
      781 gtaaaggcaa aagagagctt gattgcaaga catacaggtc gagcaaggat gaaaatcgga
      841 cttagtgatc cggtggttct gcgtggaagg gccatcgctc aacggataaa agctaccctg
      901 gggataacag gcttatctcc cccaagagtc cacatcgacg gggaggtttg gcacctcgat
      961 gtcggctcat cacatcctgg ggctgtagta ggtcccaagg gttgggctgt tcgcccatta
     1021 aagtggtacg cgagctgggt tcagaacgtc gtgagacagt tcggtcccta tccgtcgcag
     1081 gcgtaggaaa tttgagaaga cctgtcctta gtacgagagg accgggatgg acg
//
LOCUS       DAGQVA010000190         1101 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.197, whole genome shotgun sequence.
ACCESSION   DAGQVA010000190 DAGQVA010000000
VERSION     DAGQVA010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1101
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.197"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            16..279
                     /locus_tag="MIV85_003848"
     CDS             16..279
                     /locus_tag="MIV85_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963108.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(716..1093)
                     /locus_tag="MIV85_003849"
     CDS             complement(716..1093)
                     /locus_tag="MIV85_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBY2963109.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT          453 a          146 c          101 g          401 t
ORIGIN      
        1 taagaggtgg ttgatatgat aaaaaataca aaacaaatta cagtagaagt taatgaaatt
       61 ttattacaag aaatgtctaa gataactaat gacgaaaata atattttgac agatttgata
      121 aatgaatcaa ttgtaaatta tattcttgaa aacaaaaaac ataatattga aaataaagat
      181 ttagaagaag tgattaaatt ttacaaaaaa gaaaatactg aaaaacctaa aagtgcagca
      241 agagctatag ctgaagcaaa aactcatact ctgtattaat caaataaaaa agttcctaaa
      301 aactaggaac ttttttatat taataattat taatatatct caatatttat ctcaaatcta
      361 tcaatataag catgtttaat acaatctatt gtatacttat cttaccctag aaataatcaa
      421 aacaaaaata aaattatgcc ctttatatct aaaacaatta atttacatga ttaatataca
      481 aaaattctga cttttaaatt cgtatacaat atcaaactaa aataatatta atgacaaacc
      541 caatataaat taaattcaaa caggtttgat tttacatcaa acttattgta ttaatattaa
      601 ataacaagac aaaaatattt ataaaaatca caaattttac ataaaacttt atatttgatt
      661 catttaacta attattgtaa aaactattta ttttatgata attaactaca ccaaattatt
      721 catctttttt aatatcctta acccattttt caacagagtt caattcttct tcatttaccc
      781 cctttttgaa caaggatttc ataaaactct caatagaact tccatgcata ttatctaaaa
      841 aagtttttgt ttcaaaatgt aaatactctt cttctccaat aagaactgta taatgtgtat
      901 gtctatcaat ttttcttgca cttaagaatt gcttatttac taatcttgat aaaagtgtta
      961 gtgttgtagt ttgcttccaa ttatatagtt tttccatagc ttcaatgaca tcttttgatg
     1021 ctactgtaaa atctgaactc caaataaatt tcatgacttt taattctgct ggtggtatct
     1081 tagtaatagt catatgattt t
//
LOCUS       DAGQVA010000191         1061 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.198, whole genome shotgun sequence.
ACCESSION   DAGQVA010000191 DAGQVA010000000
VERSION     DAGQVA010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.198"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            329..469
                     /locus_tag="MIV85_003850"
     CDS             329..469
                     /locus_tag="MIV85_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963110.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(466..837)
                     /locus_tag="MIV85_003851"
     CDS             complement(466..837)
                     /locus_tag="MIV85_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBY2963111.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT          420 a          107 c          123 g          411 t
ORIGIN      
        1 ctaaagaatt aaaagaaagt caaataaata taaaaaaatt atatatttat aaaaaatttt
       61 ataataaaaa tcatcctgaa aaatatataa aaatagaaaa aacatacaag attctacaat
      121 aatagatttt tttgttatta ttacgagttt tttattgcaa ctgtagaata aaagtattat
      181 tatataatta agataattat ctagggaaat tttggataat caaaatatat tttataaaat
      241 caaaatacaa ttacataaac tttattaaaa atttgttggg aatttctgac taacattaag
      301 aacgtaagtt tgttggggga tggtatatgt ggaaaagtca aacactactg ttacaaaaaa
      361 agaaaaaatt gaagatatag gaatgaaatt agaacattta ttgagtgaag atattacttt
      421 ttatgaatta ttacttgaga ttttgtataa agaaaaagaa gagaattaat tctcttcttt
      481 aaggaatctt tttaaatagg cattatcaat cattttttct atagcttctc tatcttcttt
      541 ttcaagagaa tatatttttt ctaagagctt ttttgttttt tcacttactg ataagttctc
      601 tatgattaat ttatcttctt tgcttatttt tgtattatca tttacgccta ataaataatc
      661 tgttgatgtt tctaatgctt ttgctaatct aactattatt tcacttttag gttctcttaa
      721 attattttca taacgtgaca agctagcctc agttataccg actttagtag caagttcttt
      781 ttgatttata tctaattctt ttcgtagatt tgctattcta tctcctaaac tttccatatg
      841 tacatcactc cttaccgaaa ttataagtta ttttgataaa aagtaaaata aaattaccaa
      901 aaatataaaa aaaaaaggtt aaaataataa aatatattga aaattaccat ttgtatatgt
      961 ataatatgaa ttatacaaat ggtaatttga tgagaggtgg tatgttgaaa taagaaactg
     1021 aattaattaa taaatacata gaaagttttg aaaaccttta a
//
LOCUS       DAGQVA010000192         1055 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.199, whole genome shotgun sequence.
ACCESSION   DAGQVA010000192 DAGQVA010000000
VERSION     DAGQVA010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1055
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.199"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(91..801)
                     /locus_tag="MIV85_003852"
     CDS             complement(91..801)
                     /locus_tag="MIV85_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963112.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYKIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT          367 a          141 c          111 g          436 t
ORIGIN      
        1 aaaattaaat ttgaaaaaac aaaactctaa aaactaagct ttaaaaagtt aagtttcaaa
       61 aataaaattc tagagattga acttcaaaaa ttaagattct aacatatacc ttgtaaattt
      121 tcctacaacc tcttgatatt ttttacggct tataggaatt ttttcattct gaactttggc
      181 ataagtttga gttatactat ctacatggtt tagattgaca atataccttt gatgcgtacg
      241 tataaaatta gagggaagaa cagtttccat atcatttaat tttccgtagt attctaatgt
      301 tttatcaaag gtaactacag ttaattttct tagctcactt ttaaagtaga ggatatcttt
      361 tgtattaatt ttacaaagat tagttccaat ctgaactgta ataaagtttt ctttccattg
      421 ttctaatttt tttagtgctt cttttaatac tttacatatt ttttcagttt tataaggttt
      481 taagatatag ttcaaagctc ctacatcata tccatgaaat acatagtcag aaaaacctgt
      541 gacaaagatg attatagtat cttttgaatg ttttcgtata gtttttgcta tgtcaacgcc
      601 attacttttt ccaagttcaa tatctaaaaa aataatatct atgtaataat tttcgtgttc
      661 tagattgtat actagacttt ctccatttga atattctttt attttatagg ggtagcccca
      721 caaatccatt tctcttgtaa tgattttatt cagcatgttt ctttgttgtt tttcatcatc
      781 acaaatacaa atcgaagtca attttttatc tcctttcaaa ttttatattt atatagttaa
      841 gtatataata tattttgcta cctagatata taaaatgaaa taacaattat atccagatag
      901 caaaataaaa ttttttatat tagtatactt acacttaaaa ctattctatt aaacttattc
      961 tgaagtgcta atgattttct tattaaaaaa tctaacaatc tttcttatta taaaatacaa
     1021 atgcttttat tattataaaa agtaatgatt ttatt
//
LOCUS       DAGQVA010000193         1031 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.200, whole genome shotgun sequence.
ACCESSION   DAGQVA010000193 DAGQVA010000000
VERSION     DAGQVA010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1031
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.200"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            637..>1031
                     /locus_tag="MIV85_003853"
     CDS             637..>1031
                     /locus_tag="MIV85_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963113.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKVRSITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNI"
BASE COUNT          443 a           67 c          133 g          388 t
ORIGIN      
        1 aacataaatt tataatataa aattgtttta agctcccttt ccccaaaata ggaaattttt
       61 attagtattt aataatgatt tttaattttt aatataatat taaagaatta tttaagaata
      121 tttaatctct aaagcttaaa ttacaataat attataaaaa taaaagtgat atattgtgta
      181 ataatcgaaa ttttatactt tggttaaaat aattttatat atagtgccta atgtataacc
      241 taatgctcgt agacaataat gtggatatta tcaaatttat ttttataata gaaattttaa
      301 tttatatcta tattaaattg ttaaagatat aattatgaga ataaaaaata tagccttgaa
      361 ttatataatt gtatatgctt atctttatac agtaaataaa aaatcaaatg aaataccaaa
      421 taaagtgtat atcttaaaac aatttactag agatacaagg atgctatgtg aattttgaag
      481 tgtgcagttt agataataaa tatatataaa taataaagaa aatggattta tagtatttaa
      541 aatttcttat aagggtaaaa aatgctatta gaaaatgtac taaaaatatt tttccaattc
      601 tttatagaaa aataatgata tttaggagag attgtaatgc aaattgatgt attgataatt
      661 gatggagata agaatagttc tcaagagctg aaaaattttt tagaaggaaa ggggataaat
      721 gtctatttag catataattg taaagatgct attataaaaa tatttagcaa gaaatttgac
      781 ttaatatttt tagagataat tttagttgat ggtgatggtt gggatttttg taaaaaagtt
      841 agaagtataa ctacttgccc aattattcat ataacttata taaatgaaaa tcaaagtatt
      901 ttaaatgctt taaattctgg aggagatgat tatttaataa agcctttaaa tttagaaata
      961 ttatatgcga aagtgaaagc tattttaaga agaagagatt tatttttaaa taataataaa
     1021 aataatataa a
//
LOCUS       DAGQVA010000194          994 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.201, whole genome shotgun sequence.
ACCESSION   DAGQVA010000194 DAGQVA010000000
VERSION     DAGQVA010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.201"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            282..458
                     /locus_tag="MIV85_003854"
     CDS             282..458
                     /locus_tag="MIV85_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963114.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT          390 a          123 c           98 g          383 t
ORIGIN      
        1 ttattaaata gttgcatata actttattta tcttgaatct tatttttaaa aacaattata
       61 attttagaat attttctatt ctcaaacaag catgttgaat aatgaagcat cttctagtat
      121 tatatacttg tagaataaaa ctaaattggt aaaactggga atatttaacc ttaaggagtt
      181 aagttataga aactagtact aaaaaatttt ataaattatg ttaattgact aatagaatgc
      241 gactttttat ttttactaaa ttttttaggg ggatggataa tatgtttatt ggagaaatag
      301 acaaatgtac acatatacta actgcttaca tcagtagttc atatgattat tgtaattttt
      361 tagatacaca gttagatgat tttatatcag aatatggaga aacggtagtt gaaacctgct
      421 tacatcaagt cttattatta gtaagtagat acaattaaaa ctaaattttt ctagaaaaac
      481 ctttttagat ttatctactc taataaatat ataatttttt gtactttata agtaactata
      541 acttctgcta aagtaaagat gtattgggag tacatcttta ctttcccatt atagaagtta
      601 aaagcataca ccataaaatt aatcatccaa tacaaattat atatttccta tgtctaactt
      661 aatttacaag aatcattcta tatgcatatt ctgcaatcca ctaaacatgg ctctaaacct
      721 ttactatttt atacattctc tataaatcat acaaatcata tataaaatcc ccctaatatg
      781 tttaaaccac ctataaaata acaccaatat ttagaatatt caatatcaac tgcataactg
      841 gtcaataaaa acgtataact agacaaattt caatatttat ataaataata caagaaaaac
      901 aagcatttta tttatataag ttttttattt tttgtttata ttaaaaaact atattgatta
      961 atttatttta tttagtaatt ataaaaattc gtct
//
LOCUS       DAGQVA010000195          973 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.202, whole genome shotgun sequence.
ACCESSION   DAGQVA010000195 DAGQVA010000000
VERSION     DAGQVA010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.202"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(274..741)
                     /locus_tag="MIV85_003855"
     CDS             complement(274..741)
                     /locus_tag="MIV85_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBY2963115.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDYFDTFVERLSTMRDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          373 a          170 c           66 g          364 t
ORIGIN      
        1 gtatatatga ttctacagct tgatagtaag tataattatc ttttataagc taatacttat
       61 atttttctaa atttaaatca tccaataaat attaaattct attataatat gtaaggaaaa
      121 tcatgcactt tttaaaaatc caaataaaat tataacaaat attatattct gtatcttaca
      181 aaaacaaaaa ctgtaagtaa atttgtttcc atacaagttt acttacagcc cttacttcta
      241 tacaaaatat agttttactt taatataatc catctattct aaaactgatt caatatattc
      301 gacagttaca tccattcttt tagctacctc atctattgaa agaccactat ctaaaaaacg
      361 tctacacaca gatgacatag tttctccaac ctcaataata tgcccatcta aatcataaaa
      421 tctaattgct ctttgacccc acctatgctc tatagctaga tgaacataat ctatatctct
      481 cattgtactc aatctttcaa caaaagtatc aaaataatct tcctcaaaat acagctcagc
      541 atcatttcca ttgaacttaa cttcactgtc actcttatta ataaactcta accaaagctt
      601 tttttcttgt aatgatatat tcccttctaa tacaacattt tctccaaaat cacagattac
      661 ctttaacccc aaaacatcat aataaaactt ttttgatttc tcaatatctt caactactat
      721 taaaacattt aaaaacttca tattacctcc ttaatataca catactttat ttataatata
      781 taattagaat taaactataa aggtttcaat aaggtctagt ataaagaaaa aaattataag
      841 tcttattgaa atagttaagt taattgtatc atataatata aattttaatc ttgtaaaaaa
      901 cagacacatt catactttta ggtttaaatc tatatgtatt cttattaatt ttgctaaaac
      961 tgttattttt gta
//
LOCUS       DAGQVA010000196          877 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.203, whole genome shotgun sequence.
ACCESSION   DAGQVA010000196 DAGQVA010000000
VERSION     DAGQVA010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.203"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(203..412)
                     /locus_tag="MIV85_003856"
     CDS             complement(203..412)
                     /locus_tag="MIV85_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963116.1"
                     /translation="MHINQTGFISNGLGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFESIATLVRGGSSWSFNFIV"
     gene            complement(609..>877)
                     /locus_tag="MIV85_003857"
     CDS             complement(609..>877)
                     /locus_tag="MIV85_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963117.1"
                     /translation="LPTNASASKVEDSSMKVMYSEKQVTDMDKLYDMAKNGITDVKSS
                     NEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSKIYSKTVF"
BASE COUNT          281 a          143 c          104 g          349 t
ORIGIN      
        1 aaatatttaa aaacatccca atatacattc tttataattt gttaaaataa aattcatata
       61 ttaagaaata ttaatagtaa ataagcaatt gttgctataa cttaggaatt atctttaaaa
      121 acacaaatta atttacattt tctaatttta aagtatatgt atatctttaa ttttaataaa
      181 attcacttaa aatattttaa ggttaaacaa tgaaattgaa tgaccaagaa cttcctcctc
      241 ttactaatgt tgcaattgat tcaaacccac aattgtattg aactgaatct ctacctactg
      301 gtttccaact agaaggtgca ttatatgaga aagaatttga tgttggctct ttcttttgtt
      361 gctgcttaat tcctagccca ttagaaataa atccagtttg atttatatgc acccttctat
      421 ttgttacacg aatctggccg tctgcaatag accagtttcc agaaacttta ctaacggaaa
      481 tatattgaaa tgctccatct ccttttgata ttgtatatgt aactgtacca gatgctttta
      541 caccaccagt tttatcccat ccatcttctg atatacttgc ttttctaaga ggctttattg
      601 tattagtatc aaaaaactgt cttagaatat atctttgatg ttaaattttt agattgttta
      661 acttctaata attgagttgt tgatatagaa tcaacgtata tggactctcc tgttcttgca
      721 tttttgatta tacctttttc attggaactt ttaacatcag taattccatt tttagccata
      781 tcgtataatt tgtccatgtc tgttacttgt ttctctgaat acattacttt catagatgaa
      841 tcttctacct tactagcact tgcatttgtt ggtaata
//
LOCUS       DAGQVA010000197          873 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.204, whole genome shotgun sequence.
ACCESSION   DAGQVA010000197 DAGQVA010000000
VERSION     DAGQVA010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..873
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.204"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            256..369
                     /locus_tag="MIV85_003858"
     CDS             256..369
                     /locus_tag="MIV85_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBY2963118.1"
                     /translation="MIMGRHLWNPSYFVATVLENTEEQIGKYINNQKKQVK"
     gene            371..>873
                     /locus_tag="MIV85_003859"
     CDS             371..>873
                     /locus_tag="MIV85_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2963119.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNVLKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNAAISKEPSGR
                     YYVSLCCT"
BASE COUNT          368 a           94 c          143 g          268 t
ORIGIN      
        1 ctgtgcttac gtgaaagtgt aagaagttca taagagaact gcataggtag tagcgaactt
       61 atgtgaacga caacctcaaa aatgataaaa gttaagaact tacggttctt atatatgtta
      121 tttaaaaata aatataaaaa accttcaaaa tacttgtttt aagtaattgc atattttaat
      181 attatgataa gtgatgaaaa atggaagtta ctcatggtag aggatatgca tatagtatgt
      241 caaatataga catccattat tatggggaga catctttgga atcctagtta tttcgttgct
      301 actgtattag aaaatacaga ggagcagata ggaaaatata ttaataatca gaaaaaacaa
      361 gtaaagtgag gtgatagtag tggaaaaagc ttataagttt agaatgtatc caaataaaaa
      421 acagcaagag ttaattaaca aaacttttgg atgttgtaga tttgtatata ataagtatct
      481 tgctaaaaga atagaagttt ataaaaacga taaagaaact tttacttata aacagtgtag
      541 ttctgatttg accaatttaa aaaaagaatt aaagtggctt aaagaacctg acaaattttc
      601 actacaaaac gtcttaaaag atttagataa tgcatataaa aaattcttta aagaaaaagc
      661 aggatttcct aaatttaaat caaagaaaat taatagattt tcatataaaa ctaactttac
      721 aaatggaaac attatgtatt gtggtcaaca tataaaacta cctaaacttg gtatggttaa
      781 gataagggat aaacaagtac ctcaaggtag aatacttaat gctgctatat ctaaagaacc
      841 aagtggtaga tattatgtat cattatgctg tac
//
LOCUS       DAGQVA010000198          847 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.205, whole genome shotgun sequence.
ACCESSION   DAGQVA010000198 DAGQVA010000000
VERSION     DAGQVA010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.205"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            58..813
                     /locus_tag="MIV85_003860"
     CDS             58..813
                     /locus_tag="MIV85_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HBY2963120.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
BASE COUNT          357 a           55 c          147 g          288 t
ORIGIN      
        1 attacagttt atatattata ataaaataaa ttgttaattt taaaagaggt gaattttatg
       61 gcacatatat gctttgagga tatttgttat ttgttattaa aagaagcaat gaagttaaag
      121 ttaataccac ataataaaat tgtattattt gaagatgatt tatcaatagg taatattttt
      181 gatgtaaata actacgaatt aagagaaaat atttttaaga ttagaaatgt ttttgaaaat
      241 aatccgaaac tattattcaa gccagatttg ttagaagata ggaaattatc aaaatgtaga
      301 aatataataa tatggtgtgc aaataaccca aaagatttgt gtggagtata ttatgtagtg
      361 agtaagtttc aagataaaaa tataaagatt gcattagtag atgaaaaaaa gacagaagat
      421 gctctaatta gatattcatt taccagtgaa atgtctccag aagattttcc attcttttta
      481 gataagacac tagaaattgg ctttaatgaa aaactagaat ttaaaaataa atgggatgtg
      541 ttagttaaag aaaattctat ttttagagca ttagtaggta acgaaattaa aagtgttgaa
      601 gaaacttatt ttgataaata tatattaaga aatatcagtg acaaatggca acctttaatt
      661 gaagtggttg caaactgtat gtttgaagat gaaatgcgtg taaaagattg gtttatactt
      721 tggagattag agaagatggc aagtttaaaa atagtaaaaa taaaaggaag taaaggggat
      781 ttttattctg ataaggagat aagaaaagtt taaaaattga atttataata aattgtatta
      841 aataatg
//
LOCUS       DAGQVA010000199          829 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.206, whole genome shotgun sequence.
ACCESSION   DAGQVA010000199 DAGQVA010000000
VERSION     DAGQVA010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.206"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            97..639
                     /locus_tag="MIV85_003861"
     CDS             97..639
                     /locus_tag="MIV85_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBY2963121.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT          345 a           68 c          141 g          275 t
ORIGIN      
        1 tttaccttct tcaattaata tattattatt agtaataact ttaaaattat attactatta
       61 tataaaaatt ggcttaaaag aaggtgaaaa aagtaaatga aaatatgcat aacagtaggt
      121 catagtatac taaaaggtgg taaaagtaca ggtgtaaatg gtatagttga tgaatacaat
      181 tataataaaa aattagctcc tatgttagct gagatgctta taagtcaagg taatacagta
      241 gatgtaataa tttgtccaga aaggcacttt atgtcagaaa gagaagaatt tttctataga
      301 gttccaaaag taaacagtgg taaatacgat ttattagtag agctacattt aaataaagct
      361 gatggaacac aatgtggtac agaagtgctt tactatggca ctgaaggatt agaatatgct
      421 aaaagagtat ctaatagact tggagaatta tttgaaaata gaggagctaa aaaaagagaa
      481 aatttatata tattgagaaa tacaaatcca gttgcaatac agattgaaag ttttttctgt
      541 gataatgtga atgattgtaa caaagcaaat gaatcaggtt atgattatat agcacgattg
      601 attacagaag gtatattgaa taaagatata aatatgtgag attatggtga tttaggtatt
      661 gattaatacc ttttaatatt agatataaat aaaaatacaa tgtattagta taatttaaac
      721 tttcaaaaga tagattagtt tgattattga caagagatac ctccttgaaa atattgattt
      781 atcagtatat ttaaggaggt atttaaatat aaaaatttaa ttaatttgc
//
LOCUS       DAGQVA010000200          804 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.207, whole genome shotgun sequence.
ACCESSION   DAGQVA010000200 DAGQVA010000000
VERSION     DAGQVA010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.207"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(213..692)
                     /locus_tag="MIV85_003862"
     CDS             complement(213..692)
                     /locus_tag="MIV85_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBY2963122.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT          324 a          114 c           58 g          308 t
ORIGIN      
        1 aattataaaa aagtactttt ataaaaaaat gtgcttttaa tatctactaa taaagttctt
       61 tattttaatt aaaacataat tatattttag tattataatc ttttaatttt agcattatag
      121 tttatgtatt ataccctaat atattttatt ttaaattact agttagtcac tcttttcggg
      181 ttatttatct cctatatatt aaagtgtcac acctaaatag ttaaatcatt atcctctttt
      241 atctttattg cctttacaaa tccatctgca attacaaaac tcatcagaga agttataaaa
      301 tatacaaata ctggaacagt aaaataaaat ccaaatccta aatctagaaa tctcattcct
      361 tttccagtag taccaaaagt tgaaataaac tcaattagag agtttaaaag caaaagatat
      421 ccaataatcc taaatctttt tacattctct tttacaaata ggctatattc agaactacct
      481 aatacttcta tcaatgattt tataatgata aaatatgata cacctaaaat aaacattaat
      541 attccataaa tagtaccttg tagagttgct tctccactaa aacagaggta cataaaactt
      601 ttaaatcctc ctacaacaat tactaatcct aaaagaaaaa ataaaatttg taatatacca
      661 cttagtaaat tttttataag tttattagac atcatgccaa ctcctttaaa atattttata
      721 tatagtataa tacattatat tatatcgttt ttaaataaaa atattataat taacaatata
      781 tttttattgt taattatgca aata
//
LOCUS       DAGQVA010000201          767 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.208, whole genome shotgun sequence.
ACCESSION   DAGQVA010000201 DAGQVA010000000
VERSION     DAGQVA010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..767
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.208"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(56..673)
                     /locus_tag="MIV85_003863"
     CDS             complement(56..673)
                     /locus_tag="MIV85_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBY2963123.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVGNKEIKILHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
BASE COUNT          234 a          144 c           72 g          317 t
ORIGIN      
        1 cctacatctg taattatagt gtaataactt ttatctatag ccaatatatc acctcctaaa
       61 atattgttat ctcttggtat ccaactccat tgccagttaa tacatcaatt tctccataag
      121 tttctatatc tggtggactc caagggtata tagttatttc ttgacccatt agggttgtta
      181 taccaaaatt catataattg tctttgctta taagcactct agtgtaatct aaagtcatat
      241 tacatggctt aatattactt acaaaagaat gaacttcctc aaaccaatct tgatttctag
      301 catcactttc aagatgtata ttataagtag cattattaat agttaactca taattacctt
      361 ctccaactat actatctagc caattcctta aaaatctctc tgagtaaggt aatttactta
      421 tatatttact aaaaatccta aaccttctat cttctaaact ctcattactt ttaggagtta
      481 tagacattat cttttcccat ctttttatac cacttatagt taggtcctct aaaaactggt
      541 catttgatag gtcctttaat ttatcatgta atatttttat ttctttattt cctacattaa
      601 atacttttat atattcttct ttatcttgta gaatttgtgg taagtaattt attagattaa
      661 tctctttatc caactacctc acctctcact actatactgt tactatttat tgttagatta
      721 gatttaacct catttatcat tgtatttgca atgtctaata ctccatc
//
LOCUS       DAGQVA010000202          716 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.209, whole genome shotgun sequence.
ACCESSION   DAGQVA010000202 DAGQVA010000000
VERSION     DAGQVA010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..716
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.209"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..634)
                     /locus_tag="MIV85_003864"
     rRNA            complement(<1..634)
                     /locus_tag="MIV85_003864"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          173 a          182 c          127 g          234 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtcccg tggtactctg gatcatatct
      241 aaagtcttct cgtttaacat acaggactat taccttctgt ggtgggtctt tccaaacctc
      301 ttcaattacg atacctcttc gttatgatat gtccgcaacc ccaataaaga aaactttatt
      361 ggtttgggct aatccgcgtt cgctcgccgc tacttacgga atcgaatttc tttctcttcc
      421 ttcaggtact tagatgtttc agttccctga gttcccctca ttaagctatg tattcactta
      481 atgatactta gacattactc taagtgagtt tcctcattcg gaaatcttcg gatcaaagtt
      541 tacgtgcaac tccccgaagc ttatcgcagc ttatcacgtc cttcatcggc tcctagtgcc
      601 aaggcatccg ccctgcaccc ttaataactt gaccagttaa aaaggtttga tagattagaa
      661 gctatcaact tcgataattt taaaaagtta tcagctttat atattacaaa ttagat
//
LOCUS       DAGQVA010000203          710 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.210, whole genome shotgun sequence.
ACCESSION   DAGQVA010000203 DAGQVA010000000
VERSION     DAGQVA010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.210"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     regulatory      complement(332..422)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT          270 a           73 c           65 g          302 t
ORIGIN      
        1 agcaactttt cgaagaaata tttaaataca tattaaaatt tttttatatt ttcatgggac
       61 ttcattaaaa aaatattagt tttcttacta aattgataca ttattgtatt aatgtaatgg
      121 aaatgcgatt aatttaaata aataaagaag tcattttttg taaaatagta actttttgag
      181 ataatttttc tttattttat gttataattg gtaaaatatg ttattatgtg tattttctac
      241 tgaaataaag tgatttttcc ataacaaaat gactgccaaa aaggcagtca ttatagactt
      301 ttcttaggta tacaatacac ctaggactct ttttggcaac tggctgacat agtttatgta
      361 tataaacctt agtccctata gctttgcgtc actagatttc tctagatttg cctatttagt
      421 tttaacttaa gtatacaata aataacaaat tttttaaata tcttttttgt gtataattaa
      481 atattttatt ttttaaattt aattaccaat aattacaaag attataaaca ctatagttta
      541 caattttata ataaactctt tgaaaatatt tttaatttat aaaaatataa gacaaatctc
      601 atcttaattc tatatttttc catatatttc aattttattt gtacaatata tcaatattta
      661 aaaatgtcaa ttaacgaaat ttaaataaat gatatataaa aaatttattt
//
LOCUS       DAGQVA010000204          708 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.211, whole genome shotgun sequence.
ACCESSION   DAGQVA010000204 DAGQVA010000000
VERSION     DAGQVA010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..708
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.211"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            126..509
                     /locus_tag="MIV85_003865"
     CDS             126..509
                     /locus_tag="MIV85_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963124.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
BASE COUNT          307 a           62 c           95 g          244 t
ORIGIN      
        1 ttaatcccta ctttttattt gttataacag acattctatt gtaatagaat ataaatccac
       61 aatattttta aaattagtat tgaataacta ttctcatgtt ataattattc aaaggaggga
      121 ttgatatgag gaaaaaattt tttataggta ttcttatagt tttaataatc tctgtgatag
      181 ctatacttaa tataaaaaat gataaaaatg tctttattgg agaatcagaa aattggaaag
      241 cgaaatttgt aactactgaa ggacactcaa aattagaaat aaaatataaa aatagtaaag
      301 atgtagttga acaaaaattt aattattcct atcaatttat agatggtgaa gatgcagttg
      361 tagttgtaaa aaatgaaatt ttagaagcag gtcaagaaaa agcaataaaa atacaaagac
      421 caggtcttta ttcaaataga gaatctagtt acaagctaat tatatcttgg aatggaaatg
      481 aggaaactat aaacttgaaa aagaaataac catattatca atttttaaaa aattattatt
      541 caaattctta taaaaagagt gtttagaaaa atgaaacact cttttttgta taagtttttg
      601 aaaactataa atgaaatata tcaaaatcgt tcgaaaaatt actgaaataa actcttaaat
      661 atattataaa ttaaggtata ttatacatga atttattggg agtttatg
//
LOCUS       DAGQVA010000205          664 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.212, whole genome shotgun sequence.
ACCESSION   DAGQVA010000205 DAGQVA010000000
VERSION     DAGQVA010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.212"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..>664)
                     /locus_tag="MIV85_003866"
     rRNA            complement(<1..>664)
                     /locus_tag="MIV85_003866"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAGQVA010000206          664 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.213, whole genome shotgun sequence.
ACCESSION   DAGQVA010000206 DAGQVA010000000
VERSION     DAGQVA010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.213"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            122..592
                     /locus_tag="MIV85_003867"
     CDS             122..592
                     /locus_tag="MIV85_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBY2963125.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
BASE COUNT          292 a           55 c          120 g          197 t
ORIGIN      
        1 ttaatagaag atactaaaaa agtaaaaata aaggattaat aaaaggtact gaagagatag
       61 agaaaaaaat gttaatagaa gatactgaaa aaatagaaat aaaaaattag gaggaaaatt
      121 tatgaaatat caggtttcat tattagcagt gaaggatatt gaagtatcaa aaaaatttta
      181 caaagaatta tttgagcaag aaattgaatt ggacttaggt aaaaatgtaa catttaaagg
      241 aggatttgct atacaagaag acttcgcatg gcttacaggg attaatccag atacaattat
      301 acaaaaatca aataatatgg aactttattt tgaggttgat gattttgacg aatttattga
      361 aaaactcaat tattataaag atgtagagtt tgtccataag ccactaaaac atgaatggca
      421 acaaagagta gtgcgtattt atgacccgga taagcatatt attgagatag gagagtctat
      481 ggaagttata gctagaagat atttatctga gggatactct gtagaagaaa cttctaaaat
      541 aattcaacat ccaattaaat ttgtaaagca gtgtgaaaat agtaaggaat gattgtttaa
      601 attataatta tttagtagaa attaattgta atagaactaa ttcaagataa tatataggac
      661 tagt
//
LOCUS       DAGQVA010000207          662 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.214, whole genome shotgun sequence.
ACCESSION   DAGQVA010000207 DAGQVA010000000
VERSION     DAGQVA010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.214"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..126
                     /locus_tag="MIV85_003868"
     CDS             <1..126
                     /locus_tag="MIV85_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBY2963126.1"
                     /translation="IETRLLSIDGVLDITNTMINDVKSNLTIDSNSIVVRGEVVG"
     gene            119..>662
                     /locus_tag="MIV85_003869"
     CDS             119..>662
                     /locus_tag="MIV85_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBY2963127.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHEKLNDLSS
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSSIKPCNMTLDYTRVLVSKDNY
                     MNFGITTLIGQEITIYPWSPP"
BASE COUNT          274 a           71 c          118 g          199 t
ORIGIN      
        1 attgaaacta gattacttag tatagatgga gtgttagata ttacaaacac aatgataaat
       61 gatgttaaat ctaatctaac aatagatagt aacagtatag tagtgagagg tgaggtagtt
      121 ggataaagag attaatctaa taaattactt accacaaatt ctacaagata aagaagaata
      181 tataaaagta tttaatgtag aaaacaaaga aataaaaaca ctacatgaaa aattaaatga
      241 cctatcaagt gaccagtttt tagaggattt aactccaagt ggtataaaaa gatgggaaaa
      301 gataatgtct ataactccta aaagtaatga gagtttagaa gatagaaggt ttaggatttt
      361 tagtaaatat ataagtaaac taccttactc agagagattt ttaaggaact ggctagatag
      421 tatagttgga gaaggcaatt atgaattaac tattaataat gctacttata atatacatct
      481 tgaaagtgat gctagaaatc aagattggtt tgaggaggtt cattcttttg taagtagtat
      541 taaaccttgc aacatgactt tagattacac tagagtgctt gtaagtaaag acaattatat
      601 gaattttggt ataacaaccc taataggtca agaaataact atataccctt ggagtccacc
      661 ag
//
LOCUS       DAGQVA010000208          645 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.215, whole genome shotgun sequence.
ACCESSION   DAGQVA010000208 DAGQVA010000000
VERSION     DAGQVA010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.215"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            132..>645
                     /gene="tcdR"
                     /locus_tag="MIV85_003870"
     CDS             132..>645
                     /gene="tcdR"
                     /locus_tag="MIV85_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBY2963128.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSIFEEDICFFGYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAF"
BASE COUNT          266 a           48 c           87 g          244 t
ORIGIN      
        1 attcataatg catattttca tataaaattt aatttatttg ccgattatat aattataatg
       61 actgatttaa ttccaatgtt gtcaaaattt tcaaataaat catcattata aatataagag
      121 aggatgattt tatgcaaaag tctttttatg aattaattgt tttagcaaga aataactcag
      181 tagatgattt gcaagaaatt ttatttatgt ttaagccatt agtaaaaaaa cttagtagag
      241 ttttacatta tgaagaggga gaaacagact taataatatt ttttattgaa ttaataaaaa
      301 atattaaatt aagtagcttt tcagaaaaaa gcgatgctat tatagtcaaa tatattcata
      361 aatcattact gaataagact tttgagttgt ctagaagata ttctaaaatg aagtttaatt
      421 ttgtagaatt tgatgaaaat atcttaaata tgaaaaataa ttatcaaagt aagtctattt
      481 ttgaggaaga tatttgtttt ttcggatata ttttgaaaga attatctggt attcaaagaa
      541 aagttatttt ttataaatat ttaaaaggat attctgatag agaaatatca gtgaaattaa
      601 aaatatctag acaagctgtt aataaggcta aaaatagagc attta
//
LOCUS       DAGQVA010000209          627 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.216, whole genome shotgun sequence.
ACCESSION   DAGQVA010000209 DAGQVA010000000
VERSION     DAGQVA010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.216"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
BASE COUNT          241 a           96 c           39 g          251 t
ORIGIN      
        1 actatatatc tctaataact acttttttaa catgcttaaa ctatttataa gctattatat
       61 ttatgtatta acctaataac tttttcacta aaaaataaca atctattcaa agataaacta
      121 tagtacttct tctactttgt ttcaataaaa tactaaataa atttcgtaca tccacaattt
      181 ttcaggctac actataaata tacaatcttt atcttagtta taagtttaag aatattttta
      241 gtcttatttt gtcgaatatc tttttaataa aacttcataa ttctaagcat atttttacac
      301 tgtgttttca tgtacaaaaa taatgcttac aaataaacaa cataaataaa acttaaataa
      361 gatggattct attcaacata gtatccatct tattcattca aaacctaaaa ggatttttta
      421 taatattata tattttaaaa tctaagtaac tcattatagt atcaatttca cttaaagctt
      481 acaatacact tattaatctt gttttatatt aaaaacatct acaataacaa tttaaatctt
      541 taagtgatat ccatctcaca cctaaaggag taggctctcc gcactattct gtaattcttc
      601 aatacaatca ttattatttt ttatata
//
LOCUS       DAGQVA010000210          611 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.217, whole genome shotgun sequence.
ACCESSION   DAGQVA010000210 DAGQVA010000000
VERSION     DAGQVA010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.217"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..>611
                     /locus_tag="MIV85_003871"
     rRNA            <1..>611
                     /locus_tag="MIV85_003871"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          126 c          179 g          134 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg c
//
LOCUS       DAGQVA010000211          580 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.218, whole genome shotgun sequence.
ACCESSION   DAGQVA010000211 DAGQVA010000000
VERSION     DAGQVA010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..580
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.218"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..488)
                     /locus_tag="MIV85_003872"
     CDS             complement(<1..488)
                     /locus_tag="MIV85_003872"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBY2963129.1"
                     /translation="MLNINVFWIFLPIFSTTIEWIVLKFLLNEFSELRKNRLTLNSSI
                     VIAIMIITMLNTIEFNINIKLFICIFITYVLYKINYVVDKWKSVFISLLYWMLLIGFD
                     SIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIPLLKFIRLKTKINKRDC
                     IY"
BASE COUNT          228 a           88 c           31 g          233 t
ORIGIN      
        1 aaatatatac aatccctctt gtttattttt gtttttaatc tgataaactt aagcaatggt
       61 attaatacta ttagtaatga tttagatatc attattaact ctaacttcaa caaattatcc
      121 tctaataaat cattcatatt ttttatagaa ttaagtgtca ttactatact taatccaata
      181 ctatcaaatc caattaataa catccaatat agcaaactta taaatacact tttccattta
      241 tccactacat aatttatttt atacaataca tatgtaataa atatacatat aaataattta
      301 atatttatat taaactcaat tgtattcaac atagtaatta tcataatagc aattactatg
      361 ctactattta gggttaatct attctttctt aactcactaa attcatttaa taaaaatttt
      421 aatacaatcc attctatcgt cgtagaaaat ataggtaaaa aaatccaaaa tacatttata
      481 tttaacataa tacatctccc aatacatatg ttaatttttt ctttaaatta gccattctat
      541 atttactaac tggtatatct ttaccattaa taactacagt
//
LOCUS       DAGQVA010000212          577 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.219, whole genome shotgun sequence.
ACCESSION   DAGQVA010000212 DAGQVA010000000
VERSION     DAGQVA010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.219"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..>577
                     /locus_tag="MIV85_003873"
     rRNA            <1..>577
                     /locus_tag="MIV85_003873"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAGQVA010000213          533 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.220, whole genome shotgun sequence.
ACCESSION   DAGQVA010000213 DAGQVA010000000
VERSION     DAGQVA010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.220"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..>533
                     /locus_tag="MIV85_003874"
     CDS             <1..>533
                     /locus_tag="MIV85_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBY2963130.1"
                     /translation="RAMKGSAGSGKSVNVAQDYILKLGDKKYQGANLLVVRKSEATHK
                     YSTYAELTGAINRIYGKQADKYWKTTLNPLEIKSKVTGNSIIFRGVNDAKQREKLKSI
                     NFSKGKLTWVWCEEATELMESDIDILDDRLRGILTNPNLYYQMTFTFNPVSATHWIKR
                     KYFDYKNDDIFTHHSTYL"
BASE COUNT          214 a           69 c           96 g          154 t
ORIGIN      
        1 agagcaatga aaggttcagc agggagtgga aaatctgtta atgtagcaca agactatata
       61 ctaaagttag gagataagaa gtatcaagga gctaatctat tagtagttag aaagtcagaa
      121 gctacacata agtattcaac gtatgcagag cttacaggag ctataaatcg tatttatggt
      181 aaacaagctg ataagtattg gaaaactact ttaaatcctt tagaaattaa gagtaaagtt
      241 actggtaact ctataatttt cagaggagtt aatgatgcaa aacaaagaga aaaattaaaa
      301 tcaattaact tctcgaaagg aaaattaaca tgggtttggt gtgaagaagc tacagaactt
      361 atggaaagtg acatagacat actagatgac cgtttaagag gtattttaac taatcctaac
      421 ctatactatc aaatgacatt tacatttaat ccagtctcag ctactcattg gataaaaaga
      481 aagtattttg actataaaaa tgatgatata tttactcatc atagtactta tct
//
LOCUS       DAGQVA010000214          505 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.222, whole genome shotgun sequence.
ACCESSION   DAGQVA010000214 DAGQVA010000000
VERSION     DAGQVA010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.222"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            134..241
                     /locus_tag="MIV85_003875"
     CDS             134..241
                     /locus_tag="MIV85_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBY2963131.1"
                     /translation="MGRHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            243..>505
                     /locus_tag="MIV85_003876"
     CDS             243..>505
                     /locus_tag="MIV85_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2963132.1"
                     /translation="MVVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNA"
BASE COUNT          216 a           48 c           84 g          157 t
ORIGIN      
        1 taaatataaa aaaacttcaa aatacttgtt ttaagtaatt gtatatttta atattatgat
       61 aggttatgaa aaatggaagt tactcatggt agaggatatg catatagtat gtcaaatata
      121 gacagccagt attatgggga gacatctttg gaatcctagt tatttcgttg ctactgtatc
      181 agaaaataca gaggagcaga taagaaaata tattaataat cagaaaaaac aagtaaagtg
      241 aggtggtagt ggtggaaaaa gcttataagt ttagaatgta tccaaataaa aaacaacaag
      301 agttaattaa caaaactttt ggatgttgta gatttgtata taataagtat cttgctaaaa
      361 gaatagatgt ttataaaaac aataaagaaa cttttactta taaacagtgt agttctgatt
      421 taaccaattt aaaaaaagaa ttaaaatggc ttaaggaacc tgacaaattt tcattacaaa
      481 acgccttaaa agatttagat aatgc
//
LOCUS       DAGQVA010000215          446 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.225, whole genome shotgun sequence.
ACCESSION   DAGQVA010000215 DAGQVA010000000
VERSION     DAGQVA010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.225"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            160..324
                     /locus_tag="MIV85_003877"
     CDS             160..324
                     /locus_tag="MIV85_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963133.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT          181 a           25 c           77 g          163 t
ORIGIN      
        1 tatttttatt tatagagtag aataaactgt ttttgttaag aattttgaag gtaaagctag
       61 tttaaaaaaa taaagggact aatttgtcta acgtttattg gtgaaaaata agtctataga
      121 agttataata aatatataaa aatgtatgag aggtgttata tgtttggtaa accaaaagaa
      181 agtgttagat ttttagactt taatgatgta gcagaaaagt ttggagagaa aaaggctgtt
      241 gcaatttttg atgccatagc tggaaaaaaa tctaaagaac atattatcaa agatatagaa
      301 aaattagtaa aaaatgaagt ttagatattt ataaggtata ttgagcttga gggtagctct
      361 ttataccttc ttttttatga tttttagata atattttaaa atttaaataa gaaacttatt
      421 gttatagagt aatatttata tagaaa
//
LOCUS       DAGQVA010000216          442 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.226, whole genome shotgun sequence.
ACCESSION   DAGQVA010000216 DAGQVA010000000
VERSION     DAGQVA010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.226"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..>442
                     /locus_tag="MIV85_003878"
     CDS             <1..>442
                     /locus_tag="MIV85_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBY2963134.1"
                     /translation="TEFEYFDNMRLSQDFGFNHANVVLRIGFKDGELYICNEIYVHEM
                     DTSEIIKIANSIGLEKTLFMYCDSAEPDRIKMWKNAGYKAKGVKKGPGSVKAQIDYLK
                     QLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEFMDDAMAA"
BASE COUNT          177 a           50 c           92 g          123 t
ORIGIN      
        1 ctacagaatt tgagtatttt gacaatatga ggttatcaca agactttgga tttaaccatg
       61 caaatgtagt acttagaatt ggctttaagg atggagagtt atatatatgt aacgaaatat
      121 atgtacatga aatggatacc tcagaaatca taaagattgc aaatagtata ggtttagaaa
      181 agactctatt tatgtactgt gatagtgctg aaccagatag aattaagatg tggaagaatg
      241 caggatataa agctaaagga gttaaaaaag ggccaggaag tgttaaagct caaatagatt
      301 atttgaaaca attaagaata catgtacatc ctagttgcac taataccata aaagaaatac
      361 aacaatggaa atggaaacaa gacgaaagaa ctggattata tcttgatgaa ccagttgagt
      421 ttatggatga tgcaatggct gc
//
LOCUS       DAGQVA010000217          405 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.228, whole genome shotgun sequence.
ACCESSION   DAGQVA010000217 DAGQVA010000000
VERSION     DAGQVA010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.228"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..215
                     /locus_tag="MIV85_003879"
     CDS             <1..215
                     /locus_tag="MIV85_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBY2963135.1"
                     /translation="IGSHPSFQLFHDLVTMFNISVDEYFYPAEKVAKSTARRQIETSL
                     DLLSDNELKIIQGTIDGILNSRENKK"
BASE COUNT          125 a           73 c           68 g          139 t
ORIGIN      
        1 atatcggttc acacccaagt tttcaattat tccatgattt agttaccatg ttcaatatat
       61 cggttgatga atatttctat ccagcagaga aagttgcaaa aagcacagct cgccgtcaga
      121 tagaaacatc acttgattta ttgagtgata acgaattaaa aattattcaa ggtacgattg
      181 acggtatctt gaacagcagg gagaataaga agtaatcagc ttcttgtttt ccccgttttc
      241 tttttagcca tatttcttca agacttattt gttgatctgc tttgcaggaa acaaataaga
      301 gccgacaatc tataagttac aataacctac aaattatcgg ctctgcgtct tagcgtctgg
      361 ctctttgata atagttactt ttccatgctt tatattgatt aaagt
//
LOCUS       DAGQVA010000218          392 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.denovo.229, whole genome shotgun sequence.
ACCESSION   DAGQVA010000218 DAGQVA010000000
VERSION     DAGQVA010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.denovo.229"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            82..>392
                     /locus_tag="MIV85_003880"
     CDS             82..>392
                     /locus_tag="MIV85_003880"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBY2963136.1"
                     /translation="MEINNIYIKLMDVRVKFSKLNLKKSGENKFANFKYFELADFLPQ
                     ATGLLEEAKLCPIVTFTNEYATLTLINGENPSEQIVFTSPMRDLQLKGSNELQALGGI
                     ET"
BASE COUNT          152 a           55 c           76 g          109 t
ORIGIN      
        1 ggtcatgagg ttgaaggttg caggattgaa tatggaacta cactaacaat tccaaaagct
       61 aaaaaagagt aggtgaggac catggaaatt aataatattt acattaaatt gatggatgta
      121 agagttaaat ttagtaagtt gaatctaaag aaaagtggag aaaataagtt cgctaacttc
      181 aagtattttg agttagcaga ctttctacca caagcaactg gattacttga agaagctaag
      241 ctatgcccta tagtgacctt tacaaatgaa tatgcaactc taacattaat taatggagaa
      301 aacccatcag aacagattgt atttacttct cccatgagag atttacaact taaaggttct
      361 aatgaattac aggcactagg aggtatagaa ac
//
LOCUS       DAGQVA010000219         9855 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.guided.114, whole genome shotgun sequence.
ACCESSION   DAGQVA010000219 DAGQVA010000000
VERSION     DAGQVA010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9855
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.guided.114"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..290
                     /locus_tag="MIV85_003881"
     CDS             <1..290
                     /locus_tag="MIV85_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963137.1"
                     /translation="DMYRDIKLDKESINKIYNRKIKIEREVNIFEDEDVIINKKVLKF
                     PKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVIILYYIYNH"
     gene            complement(618..1385)
                     /locus_tag="MIV85_003882"
     CDS             complement(618..1385)
                     /locus_tag="MIV85_003882"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBY2963138.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(2057..2872)
                     /locus_tag="MIV85_003883"
     CDS             complement(2057..2872)
                     /locus_tag="MIV85_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBY2963139.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            2964..4232
                     /locus_tag="MIV85_003884"
                     /pseudo
     CDS             2964..4232
                     /locus_tag="MIV85_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            4331..4951
                     /locus_tag="MIV85_003885"
     CDS             4331..4951
                     /locus_tag="MIV85_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBY2963140.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            5101..5505
                     /locus_tag="MIV85_003886"
                     /pseudo
     CDS             5101..5505
                     /locus_tag="MIV85_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            5630..6556
                     /locus_tag="MIV85_003887"
     CDS             5630..6556
                     /locus_tag="MIV85_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963141.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            6570..7019
                     /locus_tag="MIV85_003888"
     CDS             6570..7019
                     /locus_tag="MIV85_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBY2963142.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            7379..7786
                     /locus_tag="MIV85_003889"
     CDS             7379..7786
                     /locus_tag="MIV85_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBY2963143.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            7788..8018
                     /locus_tag="MIV85_003890"
     CDS             7788..8018
                     /locus_tag="MIV85_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2963144.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            8408..8611
                     /locus_tag="MIV85_003891"
     CDS             8408..8611
                     /locus_tag="MIV85_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBY2963145.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            8689..9042
                     /locus_tag="MIV85_003892"
     CDS             8689..9042
                     /locus_tag="MIV85_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBY2963146.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            9114..9746
                     /locus_tag="MIV85_003893"
     CDS             9114..9746
                     /locus_tag="MIV85_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBY2963147.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         3514 a         1484 c         1571 g         3286 t
ORIGIN      
        1 ctgatatgta tagagacata aaactcgaca aagaatctat caataagata tacaacagaa
       61 aaataaaaat agaaagagaa gttaatattt ttgaagatga ggatgttata ataaacaaga
      121 aagtattgaa gtttccaaag tcttggacaa agaatatgca aaaatattgg ttaagtgaaa
      181 ataagtatcc catacattct actgtaattg atgatgatag atataaatgt tgtaatgtac
      241 aatatacaaa aaatagagtg ataatattat attacatata taaccattaa tatacataat
      301 tacaaaaaaa taatgacaaa tatacataat acaaatatat cttctacttt agataaaaca
      361 gttattatga aaacttacta tctataaata atagaaatgc tagtatacca tctataatct
      421 aatgtctagt aggttttaat ggcatatttt aaatatgcca tagttgattt ataagatttt
      481 ctatatcact ttcaaaatac acactaaata gttgcttttc agatataatt gcccaattta
      541 aattttacta tctgaaaagt tttttatatt taatttatat cttcaaaaat accgtctaat
      601 atttctatat aattaattta attaatactc ttatgtaata gattaagtac tgaatttaac
      661 tctttaaatg atatttgccc tggtgctgaa acactttttg cagctccaaa agtcaatgca
      721 gaaccaaata tttcaccaca caatctactt ataacaccca ttcctgacat tgacattgtt
      781 attattggtc tatctgcata aattttaaac atttcatttg tagcttcaag tagcactaac
      841 acatcttttt cattttgcgg cataacagct attttgggta aatctgcgcc caattcctgc
      901 attctacata aacgagatac aatctcttct ttttttggag ttttattaaa atcatgatta
      961 gatataatta ctttcacttc ttttttatga gcaaaattaa ctacttcatc tatgacctca
     1021 tctcccataa ataactctac atctattaaa tctactaaac ctgtattaga aatttcttta
     1081 ttcaaagtag tataataatc tcttgatatt aatttttctc ccccttctac tacacttcta
     1141 aatgtgaata ataaagggat atcatgtata taacttctta attcatagag aacttcctta
     1201 acttctttaa tattttctac attctcaaaa aaatcaactc gccactctat aatatccaaa
     1261 catgcatctt ttaactcttt agcctctttt ataatatctt ttttattttt cccaataatt
     1321 ggtacacaaa ttttaggtct accttctcca atagtaatat tttttacttg aacttttctt
     1381 ttcatattct cctccataat cagaaattct ataggacttt aaattctatt ttctgcacaa
     1441 tttaattata cattaaaaat actatacatt ataaaaatac taatttaaaa ataattttta
     1501 ttctaattct taaaacaatc ccacatattt tagaaaaggt actctataat atacaaacac
     1561 ttctttttta cctaaattta ttttaacatc ctataatttt cacaatattc tttaaatttt
     1621 actcatataa acaatattat tctggatgct aatagaatta atctataaat catagtataa
     1681 ttatgcagaa ataactcgaa tttcactact tatgaagaga ttgaatatta atgaatctaa
     1741 atcatttgca ttacttaaga gttttgacta aagttgaaca ccatacaaaa gtagctactc
     1801 aattgtttat accccaacca agcttaagta atgttatata gattctcgaa aaagaatttg
     1861 gtatcttttt atttgaaaaa cttatattaa atttgattat cttttcataa gttggtaaat
     1921 gtcgatatat cctgtatcta caaggagtat cggcattttc tttttggaag atactttgca
     1981 taagttggca tttaaccgta taagaatgcc atcaaaagta gtaaataagt agtaaactct
     2041 agtcatacta ctaggattat aaccgttcca tttcagctct cgaagaacta aatgaaccat
     2101 gtgcataata gccaagcgtc atagtaatgt ttttatgccc cataatatat tgcaatatat
     2161 taggactcat tcctttgtta gccatatttg tacagagtgt atgcctaaag gtatgtggcg
     2221 taatctttgg tagcttgtcc tcatgggtct tattatactt cttgactaac gctcttaaca
     2281 tgctttgata atgagttgct tgttttggta atccatcttg tttaagaaat aggaagttct
     2341 ggtaaccatc aacaatgatt ggttctgctt tagcgttctt acgccgttcc acgatacgtt
     2401 caaatgattg ataagctctt tcagtcattg gaatttctcg cttaccctgt gtggtctttg
     2461 gaacttctac ataatagcca atcttagtat cactcaacaa ttgatggtct accataatgg
     2521 ctttattttt catatccaat tctaaagtca aaccgcataa ttcagaaatg cgtagtcctg
     2581 tttctaagag gataacaaca tcatcataat atttacaata agtcttatcg ctctccataa
     2641 aggataataa gcccatttcc tgttctggtg ttagagcgat ttttggttct gttgtatctt
     2701 ccaaaacatc acttaactga aaattaaatg gattctttct aatacagtcg tcttgaattg
     2761 ccatgaaaaa cgacgctttc agtgagcgct tataattgtc aatggattta taagcacacc
     2821 catcttcact cattcggata gcccagcttt tagcgtctga taatttaacc atatcaatgc
     2881 tttttgcacc tagtgggtca ttgatagtat ctatattttg atttataatt tatacatttt
     2941 tttaaaaaca gacttttaac tgtaaagaat ctatgtataa acttagctat gttgtccgtg
     3001 tatctacaaa ggatcttgac gagctaaaaa ggcgttgtga tgaagtcaaa gacttttacg
     3061 acgacttatc actcaagctc gtgcgtccct ttggggatat gttgggattg catggcgaat
     3121 ttattcctgt cagcaaacgt tacatcaatg attatattca atatgtcact tcggattttt
     3181 tggctggact tggttttgga gcgacacaaa cccttggcga acatgaggat atctatcttg
     3241 gctacaatct ggacactgga aagaatgtct atctaaaacc tgcccttgct agtcaatggg
     3301 taaagggttc tattaccaat gtgttagcgt ctgcgtttat cggttcattg ggtggtggta
     3361 aattattcag taacaatatg cttgtttact atgcggtact attcggcgga caggcggtca
     3421 tagttgaccc taaagcagaa cgcggcaaat ggaaagaaac gctaccagaa atagcccatg
     3481 agataaacat tgtcaattta accagtaatg atgaaaacaa aggattgctt gacccttacg
     3541 tcattttgag ccgtaaaaat gattctgaaa gtttagcgat tgatatccta acattccttg
     3601 ctggtatctc cagtcgtgac agtgataagt tcccagtgct tagaaaagca atccgcaatg
     3661 taacccaaag tgaacagcga gggttattac ttgtcattga tgaattacga aaagaagata
     3721 cttctatcag taacagcata gccgaccata tcgaaagttt tgtagactat gattttgcac
     3781 atctactgtt tggtgacgga aatgtgaagc agtctatcag cttggagaaa cagctgaata
     3841 ttattcaagt tgctgacctc gtattgccag atgccaacac tagctttgaa gaatatacaa
     3901 caatagaact tcttagtgtt gctatgttga ttgttattag tacctttgca ttagacttta
     3961 ttcatactga ccgctctagc ttcaagatag ttgaccttga cgaagcatgg tcttttttgc
     4021 aggtggcaca aggtaaaacg ctatctatga aactggttag agcatcgcaa gattcacagg
     4081 acaaacgaat tgaacgtttg aagaattatc tgactgaaaa cctacaacag ttgaatactg
     4141 aaatggttcg ctcatatatt cctactagtt ctattgtcaa cagctttctc agtttgagct
     4201 tactttgcag aaaaatgaca actggaaaat aataatggaa tagtttctat gtaaatatat
     4261 ttttactatc ttacctaact aattgaaaga tgatataatt taatcaaaga tttggtaagg
     4321 agggatgaat atgcatttaa ttgattttat gaatgaagat attaaaaaga agcttgttaa
     4381 aaaaacgtat aaaaagaaag agactattct ttttgctgag caagaaaatg aatatgtaat
     4441 tcttatgatt gacggtattg cagaagcatt catcttaaat gtgaaaggaa acatctcaac
     4501 tattcatctt tatagaagtg gtagtttttt tggagaaatg gaacaattta atgatgggaa
     4561 aaaacccgtt gaaattgtcg ctttcacaga ttgtaatgta tataaacttc atagagatga
     4621 ttttttaaac tggttaaggg gagattttga agctacaaaa tttctgattc gagaaatatc
     4681 tagtaaatta gttgtaaatg ctgaattaat tgaagaatta tcatctttaa gtgttaaaga
     4741 acgacttctg aggtgtatat ccttacacta ttatagaagt gaattaaatc tgcttaccaa
     4801 aaaacagctt gctagcgaag taaacgctcc aattagaagc attaatcgtg ctataaatga
     4861 atgtgtacaa gaacatctaa ttgcttatga aaacaaaaga tttagtgtaa ttaatcagcg
     4921 agaggtatta aagaatcttc ctacaacata agtataattt caaaaaagta ttgaataata
     4981 attattcaat gcttttttat ttcgggtcaa gtgacctatt tttttttatt ttttcattat
     5041 ataatactcc tatgcataat tatgttggat tgatagctaa taaaagaaag tgagaggtgt
     5101 tatactaaaa aagaagcata cttcccaact ccagacttac agtggattga agatagattt
     5161 tggatttggg ttcattacgc ttgcactaag attggacgta gagaactatt tgaaacaatt
     5221 gattttttat cttttttaag acaatcagta cttgccccat taatacagct tctcttaggt
     5281 aaattacctc gtggagttag aaaaattgaa ttggacgcac cccaatatat tgaagcatta
     5341 gaaaagacgg ttgctaacca tgaatataaa agctgtgtta atgcattgca ggctactatc
     5401 aacctgtatc ttgagttaag agaggaatta tcacaaagtc ctattgtccg aaaggttgaa
     5461 gctgaaaggg ttgcattaca gtattttcaa gatttaatca aataaaccca aagtaaaaaa
     5521 atattgaata gtaaatattc agtgtttttt catttttggt caaatgacct agattagttg
     5581 ttgtaaccat tctataatta ttttgaaagt aacagtatgg aggataacta tgagtgatat
     5641 tttaagtaga attacaaata aaattgggga taagaatata gttgataagt tatcagctct
     5701 atcaaaatca gatttgaact cacttctatt agaagtgttt gatagacaag caaatacttt
     5761 aactgcaact gatattctaa agtcatacca actaaataga tttactatcc ctagcggtat
     5821 agatccagaa gaaattcatg ctttggagtc aaaattattg agaaaagcat tcaatatgga
     5881 tatcaagacg attatgcttt ctccctctgc tccattaggt agctgtagcg tttttggctc
     5941 cgtagatcaa tataatgtag taagtgctct acgagggaca gaaacacttg cagacccctc
     6001 aaatatgttg gcaataatta ttgctgataa attaaaaaga aaagaagaaa ataataccat
     6061 acctatccac atggctacta ctgctagggt aataagagca caaaattttg taggtaaagg
     6121 tttatattca cattttggct tatattgtat ggtttcatct ggtatagata cagggtctta
     6181 cacttgtgaa aaaatgttgt tagaaaagca cttaaactat tataaagata tattaagtga
     6241 aatagaaaat gttcgtttct ctattattct acgcaaaaga aacggataca aagataatga
     6301 cggatttttc gacagaatgg ttgaaactat caaacttatt tttcctaata tagagttatc
     6361 aattcataat gatgatgttg ataataatta ttataaaggt atcaatttca aattatcggt
     6421 caaacaagga aatgaaaccg ttgaaatagt tgacggtgga tttgttgact ggacttatca
     6481 aatgcttgga aataaaaaag aacgctgttt gataagtggt attggcttag aaagatttct
     6541 tgtagctgtt tcataaaagg agaagaaaaa tggaacttat agagtggaat tatgcttata
     6601 ttaccgattt agttgagttt gcgaatgata aagaaattgc aaagaatctt cgtgacaact
     6661 tcccccaccc ttatagggag caaaacgcta gagattttgt tagtttttgt ttggcaactc
     6721 cagatgttaa acaacttagc tatgctattt tttatcaaga aagggctatt ggaagtatca
     6781 gcctaacatt tgaagaagat acctctatta ataaaaatgc tgaattaggt tactggcttg
     6841 ctaggaacta ttggggcaaa gggatagcaa caaatgcagt aaaagaaata tgcaaaattg
     6901 cctttgaaaa atacaacctt aacaaaattc atgctaatgt atattcctac aatagagggt
     6961 caagtaaagt attggaaaaa tgtggtttta agattgaaga atactgtcac aattcataat
     7021 aaagaataga aacatgattg attgccatgt atatagttta attcgaccgc aatagcattt
     7081 attagaatta acctactttt taataacaga ataagttttt cccctctatt aatttcttat
     7141 gcatctttgt atttttatga aaagctagcc aatgcatatt tccatacatc aatatggtgg
     7201 tggcttacaa ccaatataaa ttaaatacgt tttaaagaat acacattttt gccctatagg
     7261 cagagtgtgt atttttttct cttttttttg aaatttatcg aagatttaac gccctcccac
     7321 cgtgatagga gtaagcaagg ttatttaact ccttgcgatg gaaagagggt gaaatcttat
     7381 ggttgatgaa aagacaattg aacatcaatt cgacagtttc tgtaaaacag ttttgcgtaa
     7441 ctatgctaga gatatttatg acgaaaataa acgcagaaat gattatttgg tatctctcga
     7501 atctttgtca cttgcagaat taagtaaatt gagtatttta gatgattatg attctaacta
     7561 catctgtatg gtttcttacg actacaacat acgaattgaa gatgtattaa tggcacaagc
     7621 aatcggaaaa cttacaaaaa gaaaacaaga tataattcta ctttcattct ttctcaacat
     7681 gacaaatgct gacatagcaa cattgatgga tttagcagaa aataccatac attatcacaa
     7741 aacaaatgca ctaaaagagt tgaaagaact catggaggaa cattgaaatg aaacctacta
     7801 aagaagtatt accttttaca attattttac ttgctgtaca tggcgatgta aatgcaataa
     7861 acggaatact taaacatttt gaacactata tcattcgtct ttcacagaaa actttatttg
     7921 atgaatacgg aaatccctat attcatgtag aagaagaaac aaagcgaatg ctaggaacaa
     7981 aactaatcac tgctattttg agatttaatt tgtcttaatc tcgccctctc tccatgtatc
     8041 aagctatttg gtacatggag aatcactaat tatttgtcta taaaagccca taagctattg
     8101 tgatttttta tagacaaatc aatgccgact gttctttgac aactgaataa agtagataga
     8161 tacgtttgtg atacagatag ccaacaaata ctatacgcca tgaccttaat caagagagct
     8221 actatatagt gatttgtgaa taacctttgg aacggttgtt ttgccgtaac ctgtaccaca
     8281 gtataatgat acacctgtat gacacggttc tgcccataag aatgggattg gttaaaatac
     8341 caatggagct taccaaagcc atctatctac ttctgaacta cgaacataga aaggagtgat
     8401 acattctatg aacaatactg atgtacctat ttgggaaaaa tataccttga cgattgaaga
     8461 agcgtcaaaa tactttcgta ttggagagaa aaaattacgt aaacttgctg atgaaaacct
     8521 tgattctggc tgggtcatta tgaatagcaa tcgcattcaa ataaagagaa aacaatttga
     8581 gaaaatcgtt gatacacttg actttatcta atgaaattga gccttatatg ttataatatt
     8641 catatgacgt atcaagctca attcggttat tgagaggagc ttcttatcat gtcaactgaa
     8701 aaaagacgag ataataaaga tagaatttta agaactggag agagccagag aaaagatgga
     8761 agatacgcat ataagtatgt atattcattt ggtaaaccac aatttgttta ctcttggaaa
     8821 cttgtaccta ctgataaacc cccaaaggga aaacgtgatg atatatcatt aagggataag
     8881 gaaaaagcaa tacaaaatga ccttgatgat agcattgaca ctattggtaa gaaaatgaca
     8941 gtttgtcagt tatacgctaa aaagaatgga ctaagaaaga atatccgact taacactaaa
     9001 aaaggacgcc attatcttat gaagattctt aacaaggagt gattctgtga agagatgtat
     9061 tgtagtagtg gaatagtcaa aaacataata tatattaaag gagagattta aatatgacta
     9121 ttccaagttc aaataaggta tatccaagaa gtaatgatta tcaaactgta tatcttaaaa
     9181 atgtaataac aagggaaaat atagaagttg gagattacac aatatataat gacttttata
     9241 atgacccaag agattttgag aaaaacaatg tattgtatca ttaccctata aacaatgata
     9301 aattaataat tggtaagttt tgctcaatag catgtaatgc aaaatttcta atgactagtg
     9361 gaaatcactc aatgaaatca aaatccacat atacttttcc catcttttat gaagaatgga
     9421 aactcgatat caaccatata acggacgctt gggacaataa gggtaacatt ataattggaa
     9481 atgatgtgtg gataggttat gattctataa ttatgtcagg tgtaaatatt ggtgatggtg
     9541 caattattgg aacaagagca gtagttacta atgacgttcc accgtattct attgttggag
     9601 gagtacctgc aaaaattata aaaaagagat ttaataatga tacaatttca aaattattag
     9661 aaattaaatg gtgggattgg ccatataaaa aaattcaatc aaacattaag catattcaat
     9721 caggaaatat tgataaatta gtttaatatt ttataattta tttatattaa actttacttt
     9781 aataatcatt ttataagagc tttttcaaaa tttgtatatt attttaatat atataaattt
     9841 aatacaacat taaat
//
LOCUS       DAGQVA010000220         9092 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.guided.117, whole genome shotgun sequence.
ACCESSION   DAGQVA010000220 DAGQVA010000000
VERSION     DAGQVA010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9092
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.guided.117"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="MIV85_003894"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="MIV85_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBY2963148.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="MIV85_003895"
     CDS             1575..2258
                     /locus_tag="MIV85_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2963149.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="MIV85_003896"
     CDS             2255..4915
                     /locus_tag="MIV85_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2963150.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="MIV85_003897"
     CDS             complement(5096..6277)
                     /locus_tag="MIV85_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2963151.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="MIV85_003898"
     CDS             complement(6277..6939)
                     /locus_tag="MIV85_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963152.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7071..7709)
                     /locus_tag="MIV85_003899"
     CDS             complement(7071..7709)
                     /locus_tag="MIV85_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBY2963153.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="MIV85_003900"
     CDS             7888..8493
                     /locus_tag="MIV85_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBY2963154.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            8997..>9092
                     /locus_tag="MIV85_003901"
     CDS             8997..>9092
                     /locus_tag="MIV85_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBY2963155.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREY"
BASE COUNT         3408 a         1115 c         1412 g         3157 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtattacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaaggc gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atataaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggatatag aatcttaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctatagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttataa tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtacagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatat aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ctgtcctcca ttctatatcc
     6301 tatgcctctt aacgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggactgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcttta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatacttatg taaatataat acttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggaa aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagctgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatggtgaa atctataaga gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 atagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 agttttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtaatagtaa
     8701 ttattaaata agataaaaag taaatggcag atgaattaaa gtaatttcta ctatggaaaa
     8761 tacttttgag ttagaaaaaa ctatatttta gagtatgaag agatgaagct tccgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat ac
//
LOCUS       DAGQVA010000221         8007 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.guided.120, whole genome shotgun sequence.
ACCESSION   DAGQVA010000221 DAGQVA010000000
VERSION     DAGQVA010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8007
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.guided.120"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..236
                     /locus_tag="MIV85_003902"
     CDS             <1..236
                     /locus_tag="MIV85_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBY2963156.1"
                     /translation="LRSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVY
                     INRTDHEILDLKRIKKDSFYWYKEVIENNGIVK"
     gene            264..1112
                     /locus_tag="MIV85_003903"
     CDS             264..1112
                     /locus_tag="MIV85_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBY2963157.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            1773..2465
                     /locus_tag="MIV85_003904"
     CDS             1773..2465
                     /locus_tag="MIV85_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963158.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            2462..3397
                     /locus_tag="MIV85_003905"
     CDS             2462..3397
                     /locus_tag="MIV85_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2963159.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPYDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDRDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTIFTVSLPLI"
     gene            3545..4468
                     /locus_tag="MIV85_003906"
     CDS             3545..4468
                     /locus_tag="MIV85_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2963160.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            4452..5222
                     /locus_tag="MIV85_003907"
     CDS             4452..5222
                     /locus_tag="MIV85_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2963161.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            5232..6014
                     /locus_tag="MIV85_003908"
     CDS             5232..6014
                     /locus_tag="MIV85_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2963162.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSINLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            6391..6927
                     /locus_tag="MIV85_003909"
     CDS             6391..6927
                     /locus_tag="MIV85_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBY2963163.1"
                     /translation="MNLKGTKTEKNLIAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            6959..7348
                     /locus_tag="MIV85_003910"
     CDS             6959..7348
                     /locus_tag="MIV85_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBY2963164.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            7385..7771
                     /locus_tag="MIV85_003911"
     CDS             7385..7771
                     /locus_tag="MIV85_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBY2963165.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPITKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            7898..>8007
                     /locus_tag="MIV85_003912"
     CDS             7898..>8007
                     /locus_tag="MIV85_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HBY2963166.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKG"
BASE COUNT         2803 a         1062 c         1507 g         2635 t
ORIGIN      
        1 atttaagaag tcatataaat gcatgtaaac tagctattga agatggtgta gagatgattg
       61 gatattgtcc atggtcattt acagaccttt taagttcttc tcaaggtttt aataagcgtt
      121 atggacttgt ttatataaat agaactgacc atgaaatttt agatttaaaa agaatcaaga
      181 aagatagttt ttactggtat aaagaagtta tagagaacaa tggaatagta aaataaacat
      241 aaatatatat tgagggtttt agtatgtaca ttacaaaggt attaaataat tcgttgctac
      301 ttgcaaagga tgataatgat gaagaaataa tattgatggg gaaaggcatt ggccataatt
      361 ataaggccgg gtctgagtta aataaaaaag atatagaaaa gatttttgtt cttcatgatg
      421 aaaatataaa aaagagtatt atacaattgg caacagaaat agatgcagaa tattttggta
      481 tagctcaaat gataattgca tatggaatag aaaaatataa cttaaaactt atgaaccata
      541 tatatttggc cttaactgac cacattgcct ttgcagtgag acgttttaaa gaaggtataa
      601 tgattgaaaa tcactatttg ttcgaaatca aggaatttaa tccaaaagag tatgatatag
      661 gaaaatatgc tattactgtt tttaaggagg ttcttggttt agacctacca gaagaagaga
      721 ttggtaatat agcaggccat tttataaatg cacaacaaga taatccttat agtgatagaa
      781 ataagagaag tgctaaaatt gtaaatgcta ttttgcaaat agttcattat cacttttcta
      841 ttgtatataa taaagagtca ttttattata ggagatttgt aatgcatcta aaggcctttt
      901 cacaaagatt tctggctaat gaaccatcaa gagaaaaaat agattttata tatgagcaag
      961 ttcaaaaaaa ttgtaaggaa gagtatgaat gtgtgaaaaa ggtaggagct tatatgtata
     1021 aggaatactc cagagaatta ccaagacaag aggagttata tttgatgatt catattcata
     1081 agattttagg agaattatgc gaaaatagtt agaatatctt aatatgctag taatattata
     1141 aaaaattaaa aattaactac acttcaaata tgaataattg cattacttaa gggggttgtc
     1201 ttaaaattga tttttttaat taaatttgaa gctcaactcc ttttttaaac ctttatatca
     1261 ttacaacttt aatgtttata cgcctgtact tcagatgtat atctactttt tacatttctc
     1321 aacatgcaaa tctaccattt tttgcagtat gttaattgaa ataaaccttt gagttaaccc
     1381 taaatttatt ctggacttat aggaatagtt ccaaagatac tttaaaatat tttctggaat
     1441 gattgcttat ttcacatatg ttttattgtg atgttttgat ttaataaatt cttcaactct
     1501 gtatatagta aatgtattat catgtttgtt ttattcaagc acacttataa tacgcttgat
     1561 tttttcacaa tgatgaaata tactaatggg tgttataagt ataagaatag cattacactt
     1621 gaagaagcaa gtgataaatg aggtataaat cctcatatga taaactacta tttcattgag
     1681 gagcatattc taagtgatgt caagatacta caatatgact aaattcctag tgataaaaaa
     1741 gtctacgaat gagtgtagaa aggggaacta agatgaataa agttttaatt atagatgatg
     1801 ataaagatct ttgtattttg ttaaaaaaga gtatctcaat tgaacagatt gaagcaaact
     1861 attgccattc tgggagagat ggactggttg aactttcaaa acaagattat cagttagtag
     1921 ttctagacgt gatgatgcca ggtatggatg gttttgaaac tatggaacaa atacgaaaat
     1981 atagcagtat tcccatctta atgctgacat caaaaagcga taattacagc aaagtgcatg
     2041 gattgcgagc tggtgcagat gactatctaa ccaaaccatt tgaaattaca gaatttactg
     2101 ctcgtgtact gtctttaatc cgacgttaca cccgttttaa tccaaaaaat gaggaaccac
     2161 agcaactttc tttcaaaggt ttgttgattg accttgacca gcatacagtg actaccaatg
     2221 gcgaacctat gttgcttcca cccaaggaat ttggtgtact tctttactgt gcaaggcatc
     2281 agggtaagat tttgacaaaa cagcagattt atgaagccgt gtggggtgag ccatatgtat
     2341 atgatgacag caatatcatg gctattatca gtcgcctaag gaaaaaaatt gaactagacc
     2401 catcatctcc catctatttg caaacaataa aaggaattgg gtatcaattc aacacggagg
     2461 tatgaaaatg gatgaacaaa cgataattct tttcttactc ttgctgtcga ttggtctact
     2521 ttttctttcc atatttgctt tttccaagct tgggcatatt tacaagcgcc taaaagatat
     2581 agaggagata ctggctgatg tacaaattgg agacgaaaat cgtaaaatac taattaagcc
     2641 atatgatgtt atggctccat tggtttatca gcttaatgag attgtctacg attatgaaaa
     2701 taagttactt tctctgaaaa agtcggataa agctagcaaa caacttatga caagtttatc
     2761 tcatgatgtt cgtacaccat taacaactct gattggttat ctggatgctg tacacagtgg
     2821 tatagttatc gaacaagagc gggaggaata ccttgaaatc gctaggcgta gagcctacga
     2881 cctcaaggat tacattgatg ttctttttga ctggtttcgg ttgaactctg atgaatttac
     2941 gctgtcaata gaatctgtgg aaattgcaga gttgtcacgc aatattttga aagactggat
     3001 tcctatattc catgaaaaga aactgaattt tgaaattgat attccagaaa atcgactaat
     3061 ggtaaacctc gaccgagatg gatattcccg tgtggtcaat aatctggttc aaaatgttct
     3121 tgctcacagt aaggctcggc aaatcaaaat taccatgagt gaggattcca gaatggtatt
     3181 actccgtgtt gaggatgatg gtgttgggat tgccagagaa aatttaccac atatttttga
     3241 gcgactgtat aagtgtgata aaggacgttc agaaaaagga agtggtcttg gtctatctat
     3301 tgtcagtcaa atggtggagc gaatgggtgg tcagatttcc gtagaaagtg agattggaaa
     3361 gtataccata tttacagtga gcttaccatt aatataaaat tgtttttccc ccatgtgaca
     3421 tgtatacaca gggggatttt ttgtaagtta taaagttgca aggttaatac aaggttgttg
     3481 caaggttaat gtaagattga ggtggtatga taactttaat aaacaaagga ggcttttatt
     3541 atttatgaat aatttaatta ttgaaacaaa aaatctcact aagcaatatg gtgctcaaaa
     3601 gagcgtttct aatttgaata ttcacgttca gaaaggtcgc atttacggat tgctaggaag
     3661 aaacggtgcg ggtaagacga caactatgaa aatgttattg ggtctaacaa aaccaactac
     3721 tggagaaatt aaaatatttg gtcaggacat tcacaataac gagaagaagc ttcttcctcg
     3781 aattggatgt ttgattgaat caccagggtt ttatcctaat ctgacaggaa cagaaaatct
     3841 caaaatcttt gcaaggctta gaggaatacc aaaaaaaaat gcagtagaat cagcactgga
     3901 tgtagtcggt ttgccaaaca atgacaaaaa gttattttct caatactctc ttggtatgaa
     3961 acagaggttg gcgattgctc ttgccattat gcatgaccca caactgttga ttttggacga
     4021 gcctatcaat ggacttgatc ctattggtat tgcagaagta agaacgttta ttcgtgatct
     4081 ctgcacagaa cgaggtaaaa ctattttgat ttccagtcac attctttctg aaattgcctt
     4141 gttggcagat gacattggca ttattgacca tggtattttg ttggaggaag aaagtcttgc
     4201 ccaattagaa gaaaaaaaca gtaaatacat acattttgct gtatctgatg cagcacaggc
     4261 agcaaggctt ctggaaaccc aacttaacct gaaaaatttc aaagtagcag ataattacaa
     4321 tattatgcta tatgatacag atgtttctgt tgcagaaata aatcgtgctt tcattctaaa
     4381 caacattgag gtatcagaat ctcatttatg cgaagatact cttgaagatt acttcaagaa
     4441 agtaacaggg ggtgaaggaa ttgcttgata taatttcatg tgaattttca aaactcaagc
     4501 ggttaaaatt tatactgatt tctattttag gtgcttgctt atttccaatt cccgcaacaa
     4561 ttttgattgc aaaggacaac ttgccatttg agcaattgtt caaattagtt gtcaattttg
     4621 gatatttttt gctattacca attgtattaa gtattgttgc tagccaacta ttttttatag
     4681 aaagagataa tgatgtatta aaaaatcttg caacagtgcc agtgcaaaaa ggaaaactgg
     4741 ctctggcaaa attggctgtg ttgctgttta tatcattgtt ctactctgtt gcagggttag
     4801 gagctactat cattggaggt ttcattgttg gaatagtaga gggggttgct gtaaaattag
     4861 gaatgagcat tgcttttgga attatgtttt ttgttactgt acttcctgtt gtggtactca
     4921 ttgtatattt caatcgcagc tatatttttt ctattatact ttcttttgta tatgctattt
     4981 tcaattttag tatatcctta aatattatca attttgaacc aaataaccca atattaagtg
     5041 tattacctgc tcctgttata atgcgttggt ggatggcatt ttggggagat cccactggcg
     5101 aatacacggc acttagacag ccatatttgc tctcaactcc tgcttgtgta ggtattttat
     5161 gtttgataac cattatagca gtcctgctga tttgtatgat atacaaaaag caggagaatt
     5221 aggaggtatc tatgcttgat ataattacta cagaatttca aaaaataaaa agatataata
     5281 ttctatggat tggtgttgtt gctgttctgt tttcagcact attggcagtt tttcaggttg
     5341 taagttcaca cggcagtgac cctctaacgt atgagagctt tgcaaacgga gttatctgga
     5401 ataatttcag tcttagtttt ccatttggga ttacacttat tggaggatat cttattaacc
     5461 gtgaatatac agaccaaacc ttaaaaaaca tcctaactgt tcctatttca ttacgcaaat
     5521 tgctagtggg aaaattaatt gcggttggag gaattactgt attgttaagt cttttcagct
     5581 tcttatgcac atttattttg gggttgttat tttgtaatat caatatatct gttacactcg
     5641 ttgtaaaatc cttagttcag attttgtcta ttaatctgta ttgttatgtt gctgttttgc
     5701 cgattattgc ttattttggt cgtaaacaaa atgcatttct gacgggtgta gggattgcat
     5761 ttgtatacgg tttttgtggt gtgtttgttg ctggaagaaa tctgacagac ttttatccaa
     5821 tcacagcagg tcttggtcta gttggataca acaatggtgc tggtactgtt tatcagccac
     5881 ttatcggtgc tatgactttg attgtaattc taatcttgac aactattcta cttgtattta
     5941 cacctaatta tgataaagtt atgaccatat ctaagaaaaa agggataaag cataaaaagt
     6001 attctcataa ataacataaa tattgtttct attatttaag ttgctagaca gtgaaaagaa
     6061 aaaatctgtc gtacagtggc tatatgctca tgtattcaag aagctacagt tttgattttt
     6121 cataactgta gcttcttttt gtatttatta aatcacgact atcataatac ttgcaatagg
     6181 tatagcgaca agagagagta ctgtcatatg tgttttatat attacattaa gtatattcta
     6241 aaatatatgt tttaaataat atatttgaaa ataggaatat ttaaataaaa aaaataatat
     6301 tatatatagt tgacaaaaat tggcaaatga tataatatat aaatatagaa atagtaatca
     6361 ttactattat taaaaaggga ggaattaatt atgaacttaa aaggaactaa aacagaaaag
     6421 aatttaattg caggatttgc aggagagtca gaagcaagaa ataaatatac atactacgct
     6481 tcaaaagcaa gaaaagaagg ttataatcaa atagctgcta tatttgaaga aactgctaac
     6541 aatgaaaagg aacatgctaa attatggttt aaacttttac atgatggtat gccttcaaca
     6601 gaggaaaatt taaaggatgc agcagcaggt gaaaactatg aatggactga tatgtatgca
     6661 aaatttgcta aagaagctag agaagaagga tttgacaaga tagcttattt atttgaagct
     6721 gttggaaaaa tagagaaaga gcatgaagaa agatacttaa agcttttaga aaacttaaat
     6781 gaaggaaaaa tatttaaaag agatgaagaa gttgtttggc aatgtcaaaa ctgtggtcat
     6841 gtgtatgtag gtactgaagc accagaaaaa tgcccagtat gtgaccatcc aaaagcatat
     6901 tttaatataa aagctgaaaa ttattaaaaa ttatcattat taaaaaggaa tgttaactat
     6961 gaaattttct aaacaacgag aactgatttt aaatgaaata ttaaataatc cggttcatcc
     7021 tactgcggat tacctatatg aaaacttaaa aaaagataat ccaaatttaa gcttaggaac
     7081 tgtgtataga aatttagctc agctaacgga acatggcttt ataagaaagg ttagtattcc
     7141 agggtatcca gatagatttg atggtcgaat agataatcac tatcatatca tatgtgaagt
     7201 atgtggagag gtatacgatt tagaatccga agttcttaat aatttacaag aattaatatc
     7261 tgaggagaca gacataaaaa taacatctta taacataagt tttaaaggga tttgtaataa
     7321 ttgtaaaagg tgtagccaag taggttaatt ttcaaattct aaaaataatt aatgaggtga
     7381 gtttatgtgt agtgaacaaa aattttttat atgtgagact tgtggaaacc ttgtaggaat
     7441 gatacaaagt ggtggtgtac ctattttctg ttgtggaaaa cctatgaagg aacttgttcc
     7501 taatacaaca gatgcagcag ttgaaaaaca tgtacctgta attgaagtgg atggaaataa
     7561 tgttactgtt aaagtaagta gcacaactca tccaataact aaagaacatc atatagcatg
     7621 ggtgtatctt atgactgaac aaggtggtca acgcaaatgt ctagcagtag atggagaacc
     7681 tgtagttaaa tttgctttga atgatgatga taaagtgatt tctgcctatg cttactgtaa
     7741 tttacatgga ttatggaagg ctgaactgta atatttaaat aaattgagtc aaaaaggagg
     7801 ctataaatgt attttcatac aaatagcctc ctataaattt atataaattc aagttttaat
     7861 tttgtttaat gtcaatataa tataaggaga aaataatatg tcaatttata aatgtagtgt
     7921 ttgtggatat atttatgatg aatctaagaa tgataaaaca tgggatgaat taagtgaaga
     7981 ttgggaatgc cctgtatgta caaaagg
//
LOCUS       DAGQVA010000222         6849 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.guided.124, whole genome shotgun sequence.
ACCESSION   DAGQVA010000222 DAGQVA010000000
VERSION     DAGQVA010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6849
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.guided.124"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..1661)
                     /locus_tag="MIV85_003913"
     CDS             complement(<1..1661)
                     /locus_tag="MIV85_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBY2963167.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKES"
     gene            complement(1675..2604)
                     /locus_tag="MIV85_003914"
     CDS             complement(1675..2604)
                     /locus_tag="MIV85_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBY2963168.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            2833..3021
                     /locus_tag="MIV85_003915"
     CDS             2833..3021
                     /locus_tag="MIV85_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBY2963169.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            3014..3715
                     /locus_tag="MIV85_003916"
     CDS             3014..3715
                     /locus_tag="MIV85_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963170.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            3717..4640
                     /locus_tag="MIV85_003917"
     CDS             3717..4640
                     /locus_tag="MIV85_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2963171.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRVQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            4797..5720
                     /locus_tag="MIV85_003918"
     CDS             4797..5720
                     /locus_tag="MIV85_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBY2963172.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLANDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            5713..6450
                     /locus_tag="MIV85_003919"
     CDS             5713..6450
                     /locus_tag="MIV85_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2963173.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            6461..>6849
                     /locus_tag="MIV85_003920"
     CDS             6461..>6849
                     /locus_tag="MIV85_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBY2963174.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYL"
BASE COUNT         2208 a         1161 c         1013 g         2467 t
ORIGIN      
        1 gattcttttc ctgtaaatac tcctaatact aatatatttt gctttctagc ttttctcact
       61 tcattggctg tatctctcaa accaactata cccctataag ccttttctcc tcttaatgtt
      121 ctctcactac tttttcctat ctttacatca tttggtcttc catcactgag aactatcagg
      181 attttatttt cttcatctct atttattaga ccactacata tagattttat tgccaaacca
      241 tctctattat taccagcaca aaaatattca aatatatttt cactattttt tatactatca
      301 tcataatctt taaatctttt taatattgta tagtctaaaa aactagaaaa tcccatcact
      361 ctatttggta tgccaacttc tgttagagca tttgcaatta tgtaagcttg aattgccaca
      421 tttccctgat ttctactttg agagccactt gcatccaata atatatcaat aacgtatttc
      481 cctttttcat tttctatatc tttataaaat attttattat tattacttct accaactctc
      541 caagctctat tggctaatat agtaccacaa tcagaatata ctctactttt agcattttct
      601 tctattaaaa ttcttgatag actttctttt aatctcttta tttgctgtct atacattcta
      661 gcatgttctc taaattttcc taaattattt tctttttgtc ttgttacata ttttagttga
      721 aatacattat tacactcact tctaagaact ccatctgtaa agtgtattct acaaccttca
      781 tgaacatttc tacaattttg tgtctcaatt tttttaattt cacctttact caaataagtt
      841 tttccataat aatgttctat ttttgaatat atcttatttg cagtgtcttc atcaacatat
      901 ataactcggt ctgctgaatt gctacattta gaatcatcaa aatcccctac accttctaca
      961 agcatggatg aagatattga atctatatca ctttcaataa tattttcttc ttcatcacta
     1021 taaagttctt catacatgaa atcagcaaat gtatcaaaat ttacttctac actttctaca
     1081 ttattttcat caataagact attttcttct ccatttaata tgtattcaaa ataagttaaa
     1141 tatataacat ctaatgcttt taaaatctcc ataatatctt gattggtatc tatatttctt
     1201 atatcattaa ctattcttct agtcatacta tctaatgctg ggtgcttgtc catactataa
     1261 agtacaaatg tgtatttaat tttatccata atattatcat tgtgtatttt ggtaaaacgt
     1321 gaaacaatat ctttataagc atttcttctt atgtcttcta tccctggcct atctttaatg
     1381 accttttctt caactattgt atttaatata acttgaatta gacccagtat aatatctttg
     1441 ttgtatcctt ttcttattct atttgtaaga tattttttaa ctatatccca atctacatac
     1501 tttcttctag cacctgcaat tattgcaaaa tatagaccta tttcttttga agagtaatct
     1561 ttttctgata tatctatact ttcattgtaa tcaccagcta ttgtccatga taagttatta
     1621 gctctatttt caaattcata atcatcatat atccatttca taatctcacc tatattaaat
     1681 atgacttatt ggaaacacat ctatactctc ccatttatta ggtattctag ttttaattac
     1741 atctccaacc atttctttct catatacatc aaaagtcttt cctgtaagtc ccatattaat
     1801 tgcaagagtt ggttttaatc ctcttcttat agtcttaaga gatgccataa gaccacgtaa
     1861 atcaatagct ttactagata tctctccatt ttgagacttc aattgtaaat ctaaaaatat
     1921 tcctgcaaag tgtattagtt tttcttcatc agcatctgaa aattcatttt ttaaaatcat
     1981 cattaactta tcttcttcta taggaggaat atctattacc ataaatctag ataccagtgc
     2041 ttcattaagt tcttttgttc ctgcatattc ataattcata gtcccaataa atcttgttgc
     2101 tggatgtaga ttgactctct catacccagg tacatcaatt attcttctat agtctaaagc
     2161 tgaatgtacc acaactatag catcattttt tgccatatta atttcatcaa acaccccaaa
     2221 acctccatta atagcacact cataaactga gcctcttcta agtttaactt cattgtctat
     2281 aaatgtatct gtacctataa gtgttgaact gtctgtattt atatgaaatg atgtattcca
     2341 ctgaggtcta ttaaatattt cccctagatt atcagcaagt aagttttttc ccgttgcctt
     2401 tggtcccgat aataatatat tttcttcttc taaaatagct gctatacaca tagacaagat
     2461 atctttacca taaaaataag ttttagactt tgttactctg tattctaaat ctttttctaa
     2521 tccataataa tttctaaaat acagtacatc ttcaataagt ttttcatcta ccccttgcac
     2581 ccttagatta tctattatat ccatattttt acccctttta tataaatagt atttgtttca
     2641 tttcttatca ccattttagc ataaaaggat ataagctaaa attgattttt taatctcccc
     2701 cattttaagt aaaaccatgc accattttat cactacaaaa ttaagagtac tacttactga
     2761 tatttcttga ttttattcgt ctatacgtat ataatatata ctgataaatt atgaggaaag
     2821 gatgattgaa atatggaata tatgtcttgc ccagaagtag caaaaaaatg gggtatttct
     2881 gaaagaagag tacaaaaact atgtgaagaa agtcgcatac caggagtttc aaaactcggg
     2941 tatatgtggc tgataccaaa gaacgcagaa aagcctgttg atggtagaac aaaaagaaga
     3001 aaggaagtac aatatgaata gcgttttgat tatagatgat gacaaagaac tttgtgctct
     3061 tatgaaaaaa tgtgttgagc aagaaaattt atctgctatt actgcacatg gtggtgcaga
     3121 aggtctacat ttagtcgata aaaatagaca cacactctct cttgtaattt tggacataat
     3181 gatgccagat atagacggtt ttcaagttct gaaaaaaatt agagaaacaa gtaatattcc
     3241 agtaattatg cttactgcta aaaatgacga ggatgataaa gtttccggac tacgtttagg
     3301 tgctgacgat tacctaacaa aaccgttcag cataaacgaa cttatggctc gtgtcaattc
     3361 tcttattcgt cggtatacta tgctaaaccc tgcttttata acagacacag atttcataat
     3421 aataaatggc atgattattg acaagacaaa ccgaattgtt tctgtcaata atattcctgt
     3481 tcaacttaca agcaaagaat ttgatttact tgcttttctg gcttctaata agggacgggt
     3541 gtttaccaaa aaacagattt atacacaagt atgggaagaa gaatatgctt ttgacgatag
     3601 taacatcatg tctttcatca gtaaattgag aaaaaagatt gaaccagacc ccaaccatcc
     3661 attttatatt ttgacagttc gtggtgtcgg ttatcgtttt aataaggagg cttaacatga
     3721 atacaagtgt ctatctgctt ttgatattgg ctcttagcct gattattata gcgtaccttg
     3781 tttctgtcct gctacgtgtc cgagtacaac ttacacttat aaaagatgct ttagaggata
     3841 taaaaaatgg aaaccttaat cgacgtattt taacagatga aaacgacatt acaaaacaaa
     3901 tttgctatga tattaacgaa atagcaatca atagccaatt tcaacttatt cagcaaaaac
     3961 aatcagaaca agcctacaaa cagctaatga caagtctctc ccatgatgta aaaactccac
     4021 ttgcttcttt ggtcggttat ttggaagcag tagaaagtaa aattgttgta ggagaggaaa
     4081 aagacgagta tatccatgtt gcgtctaata aggctcatta cttaaagaat tttgtagaaa
     4141 atctatttga atgggtaaaa ttggattcta aggaacaagt ttttcatttt gatatttttg
     4201 acttgaatga attatcccgt aatattatat ctgattggat acctgtttta gaaagcagtc
     4261 attttgaata tgaatttgat ataccagaaa tagagtactt cttacgtata gacgcaaatg
     4321 catatacccg tatcattaat aacctattac aaaatattat tacccatagt agtggaaaca
     4381 aaatgacatt gagaattttt gaaaacaaag agcaagctca aattataata acagataatg
     4441 ggaaaggtat atcttcagac aatctcccac atatttttga aaggttgtac caatgcgacc
     4501 attcacgagc ttcaaaggga aatggtttag gcttggcgat tgcaaaggaa cttattaacg
     4561 ctcataaggg aaatattacc gccaacagca ctcccggtat gggaacagaa tttacaatat
     4621 tgcttcctaa agccctgtaa aagtacgagg ctttcttact ctaaaacaag ataaaagcaa
     4681 gattatggca aggttttggc aaggttcatg ttttataatt ctaattgtag ttgattttga
     4741 cgttgtatca actatctttt gtagaaacaa atttattaaa agtgaggaaa ttatatatga
     4801 atgattttgt gattgaaaca aagcaactta caaaaattta tgggaatcaa acagtagttg
     4861 acaaagtcaa tctccatgta aaaaaaggcc gaatatatgg tctgttagga cgcaacggag
     4921 ctgggaaaac cacaattatg aaaatgattt taggattgac ttcaatcacg tatggcgagg
     4981 tagatgtatt tggagagaat attaagggac gtgaaaaaca agtatatccc cgtatcggtg
     5041 caattatcga aacgccagga ttttatccta atctgacagg aacggagaac ttggagattt
     5101 ttgcaaaact gcgtggtaca gccgccccta attctgtaaa aagagcattg gaaattgtag
     5161 gcttacctta taaaaataaa aagctgttta gtaaatattc acttggcatg aaacagcgac
     5221 ttggtattgc caacgctatc ctgcatgacc cagaactgtt agttttagat gagccaacca
     5281 atggtcttga ccctattggt attgcggaga tgagaaagtt tattagggac ttgagcgttg
     5341 agcatggaaa gacaattctt atttccagtc atattctttc agaaatctca ttgttggcta
     5401 atgatattgg aattatcgac cacggtgttc ttttggaaga aagtagtatg agtgaactag
     5461 aaaagaaaaa cagtaaatat atcctgctac aagtttcaga tattccgaag acatcactta
     5521 ttttagagcg tcaatttaac acgaaggatt attccgttca agatgactac acgttacacc
     5581 tttataacac taatctggat atgggtgaaa tcaataaagc acttgtaatg cagaatgtaa
     5641 ctgttattag ttctcaactt tgtaatgata ctttagagga ctactttaaa aaaatcacag
     5701 gaggagaggg cattgcttaa acttattcaa acagaatttc ttaaactgcg tcgtaggaaa
     5761 cttatttggc tgatgttgtt gtctgctctc attatgccgt ttttcgcact actatacttc
     5821 aattattttg gtaaaacagg tgttgagcca ataaagtttt ataaatggtc tgcatttggt
     5881 tatacacttt ggattatttt gcctgttgtt ttgggtatat tttgcaccat gcttatacac
     5941 gaagaaaacc agtatgatat gctcaaacag ctttggattg tacctattag taaaatggga
     6001 tactttttta gtaaattttt cgttgttttg atttactcta tttgttttat gctgattaca
     6061 gccgttgctt ctgtgttatt tagtgtactt tctggatatg tcgtatttag ctgggcaagc
     6121 attttatatt tgttgaaaaa atgtttagaa attggtgtaa tcactgcttt tgtaatgttg
     6181 ccgattttgg caatcgctac atctcaaaaa ggatacattc tcccaatttg tatcacattg
     6241 gtatatgcct tttccggttt tgttataatg acaataaata tgtatttaca cccattatcc
     6301 agtatgggag ttattatcat gagaaataaa gacattccag gtcttatatt ttcacaggaa
     6361 attaatgtcc cattagcatt tctttgtatt tgtatttgga gtattgtatc agtattgttt
     6421 gcaaatattg cactaggaag aagaaagtga ggtgtagata atgtggaaat tactttgggc
     6481 tgaatgtcaa aaaattcgtc gttcaaaaat tgtttggatt acagtttttg catccattat
     6541 gatagcagtc atagtttttg caggggggca ggatgtatat aatgacccag atttacatta
     6601 tggcttaaag agcgtttatg acggttcacg gtatatagac aatgcaggtt ggtatatgga
     6661 cgcagtacaa ccttggtcaa ctttttttgt tcttcctgct gtcattgccc tattaggaag
     6721 ctatattatt tgtcgtgaag aagaggagga cactattaaa tccctgcgtc ttattcccat
     6781 aaatgaaaca aatttaacca tagcaaaaat gattattact tttatattca gtatacttct
     6841 ttatttgtt
//
LOCUS       DAGQVA010000223         4483 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.guided.144, whole genome shotgun sequence.
ACCESSION   DAGQVA010000223 DAGQVA010000000
VERSION     DAGQVA010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.guided.144"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            298..1398
                     /gene="vanG"
                     /locus_tag="MIV85_003921"
     CDS             298..1398
                     /gene="vanG"
                     /locus_tag="MIV85_003921"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBY2963175.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            1395..2201
                     /locus_tag="MIV85_003922"
     CDS             1395..2201
                     /locus_tag="MIV85_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBY2963176.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            2219..4357
                     /gene="vanT"
                     /locus_tag="MIV85_003923"
     CDS             2219..4357
                     /gene="vanT"
                     /locus_tag="MIV85_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBY2963177.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
BASE COUNT         1637 a          500 c          784 g         1562 t
ORIGIN      
        1 ctttaaggtt attattccga ttgtaggaaa tttgtaagaa tttaagtata aaaaaatagg
       61 aaattcttta ggataaataa ataaagagca ctcttgttat tgatataatt actgtatcaa
      121 aacaagagtg cttttatttt gatacagtaa ttatatcaat agaaaaatgt gaaaatatat
      181 tatgtggaac agatgcaatt gtaagtgaag gttgattgga tttgaaatag aaaaagtatt
      241 ttaacatgtt tctgtagatt gtataaaaat aaataaatca acaaaggaga atcaaagatg
      301 aataataaaa aaattgcagt tatatttggt ggaaactcaa cagaatatga tgtatcatta
      361 caatcagctt ttgcagtact tgagaatttg aatacggaaa aatatgatat tataccaatt
      421 ggaattacaa gggagggtaa ttggtatcat tatattggag attataataa tatccagaat
      481 aacacttggt ttgaaaggga tactgatata attccagtta ttgtttcgca gaaccgtgtc
      541 aaaaatggta ttattgaatt tttaattcct gatgctgttt ctcagaatca tattccaaat
      601 agtgctattg aatcatgtga aaatgatatt aaatacacta aacttgattt tgtgtttcct
      661 gtactgcatg gaaaaaatgg agaagatgga acagtgcagg ggttatttga attggcaggt
      721 atacaggtta taggatgtgg tactctttct tcagcattat gtatggacaa agacaaatca
      781 cataaacttg ttcattcaga aggtattaaa gtaccaaaat caatattact aaaatactca
      841 gataaattta atgtggctga actgtcaaaa gacttaactt atccattatt tataaaacct
      901 gtgcgtgcag gttcatcatt tggtattagt aaaatttata aaaaagaaga gttacaagta
      961 gcagtagact tggcttttga acatgataat gaagtaataa ttgaggaaaa tattgatggt
     1021 tttgaggtag ggtgtgcagt tttaggaaac gatgacttac ttgttggaag agtagatgaa
     1081 atagaattgt caaaaggatt ttttgattat acagaaaaat atacattgaa aagttcaaaa
     1141 attcatatgc cagctagaat tgatttggat tgtgagaaaa gaatacaaga gacagcaaaa
     1201 attatttata gaactcttgg atgttctgga tttgctagag tagatatgtt tttaactcca
     1261 tctggtgaaa ttatttttaa tgaagtcaat acaattcctg gctttacttc tcatagtcgt
     1321 tatccaaata tgatgaaagg tattggattg tcttttgaag aaatattgga caagataatt
     1381 gaggtgtaca taaaatgatg aataatattt tattagataa aaataaagaa gataaaatga
     1441 caaatactat cttattgact aaagataaag tttatgatgg gaatctaatt ctagtaaatg
     1501 cttttttacc agttaaaaca tctgaagata tagatttaat tcctgtagat acaaggtttc
     1561 caagtattct tatgaaacgt gaagctacaa acattttaca aaatatttta aaaagtatat
     1621 gtggaataaa tgaaatagta cctgtaagtg gatatcgtac tgcagaggaa caacaagata
     1681 tatattcaag ttctctgcgt gacaatggaa aagactttac taaaaagttt gtagcacttc
     1741 caaatcacag tgaacatcag acagggcttg ctattgattt agggttaaag aaagaagtta
     1801 tagattttat ctgccctgaa tttccttata atggtatttg taatgagttt cgtaaggcag
     1861 cactacatta tggttttata gagcgttatc agtgtaaaaa agaagaaata acaggaatat
     1921 ctcaagaacc atggcatttt cgttatgtgg gatatccgca ttctgagatt atcaataaaa
     1981 tgaatctcgc tcttgaagaa tatatagaat atattaagag attttcgtat acaaattgtt
     2041 taaaaataga agataaagaa aaaattatag aaatctttta tgtgcctatt catactaaag
     2101 aagaagtgag aatctctata cctgaacaat gtgtatatca aatatcgggt aacaataagg
     2161 atggttttat tgtgacattt tggagaaata gaaaggacta agaaatggag gaacaagaat
     2221 gattaggaat aaatcttatg cagggcttga ttattttagg attatagctg cattacttat
     2281 aattgcaatt catacatctc cattattatc atatagtaaa atggctgact ttgtgttaac
     2341 tagtataatt gctcgtattg ctgtgccatt cttttttatg ctatcaggct tttttctaat
     2401 ttcaacatat aattataatt gtaataaact gaaatctttt ctaaaaaatg tattatttat
     2461 ttacgggata gctattgtaa tttatattcc cttaaatatt tacactggat atttttccat
     2521 gaataattta gtgcccaata ttattaagga cattgtattt gatgggactt tatatcattt
     2581 atggtatcta cctgcatcaa ttattggtgc aagtattgca tactttcttg taaaaagact
     2641 aggtttaaag tactcactag taatcactat tgttatttat gtaattggta tgtttggtga
     2701 tagttattat ggttttttag aaaaaatacc actattaaag aatttatatg ggtatatttt
     2761 tgaagtatca gattatacac gaaatggtat attttttgca cctgtatttt tcatacttgg
     2821 tggaataata tctaataaat ctaattatat gtcaactaaa aatagcttga ttggatttct
     2881 tatatcattc ttacttatgt tatgtgaggg aatgttttta cataaactag gggtacagcg
     2941 tcatgatagc atgtatatta tgttattgcc atgtatgtat ttcttattta cagccttaac
     3001 atttttgaaa ggttctcgag ctaggttatt gcgaacatca tcattaatta tttatattat
     3061 acatcctatg atgattgttg ttattcgtat gttttctaaa atattcggaa tacaaactgt
     3121 cttggttgac aatagcctta ttcattatat agtggtaagt atagcatctt ttatagcttc
     3181 tataattatt atattgattc ttaaacctct aaaaaaagac ttgaaaggag aacataaggt
     3241 aaataccaat agagcttgga ttgaaattga tttaaataat ttggaacata atgtaaagat
     3301 gatacaaaaa gctatgccag aagattgtga attgatggca gttgtaaaag ctaatgccta
     3361 tggtcatagt gcttttgaag tagcgacttg tgcaaaccaa ataggtgtaa aagcatttgc
     3421 agtagcaaca atagatgagg ggattgattt acgtcgatat ggaatactag gagaaatatt
     3481 gattcttgga tatactaacc caataagggc aaaggaactt cataaataca atcttacaca
     3541 gagtgttatt gaccttaatc atgctatctc tttaaacaaa cagaaataca acataaaatc
     3601 acacattaaa attgatacag gtatgcacag actgggtttt gatgttaatg atgtgaggtc
     3661 aattttaaag gcatttaaat taaaatactt agatatatgt ggcatattta cacacttgtg
     3721 tgtttcagat agtctgaaag atgaagatgt agactttaca aataaacaaa ttgaatgttt
     3781 ttataagtta attgattttc tgttaaaaaa aggtataaaa attcctaaag tacatattca
     3841 aagtagttat ggttttttta attatcccaa tcttaagtgt aattatgtaa gaattggaat
     3901 tgcattatac gggatattaa gttctccaaa tgatacgact aaattgcaac ttgatttacg
     3961 acctgtttta tccttaaaat cacaagtaat tcttattaga aaaatacaaa aagatgatag
     4021 ttttggatat ggaagagtct ttattgcaag cagagatagc gtaattgcta tattatctat
     4081 tggctatgcc gatggtatac ctagaaattt atcctgtgga aaaagttacg taataataaa
     4141 tggttgtaga gcagcaatag tgggtcgaat ttgcatggac caacttgctg ttgatattac
     4201 agatatacct aatgtagaag ttggtaatac ggcaataata ataggaagag ataatttatc
     4261 tgaattatct gcttctgaag ttgcaaataa ctcatgtagt atatcgaatg aattattgag
     4321 cagagtagga agaaggttaa atgttataaa gaagtaactc aattaaatag taatatttgt
     4381 tgtactgtgt aatttatttt actctgacta gacattttta gtaatattat gtctaatata
     4441 tattttttat aacttacatg acaatttaag ttataaaaag gtg
//
LOCUS       DAGQVA010000224         3320 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.guided.160, whole genome shotgun sequence.
ACCESSION   DAGQVA010000224 DAGQVA010000000
VERSION     DAGQVA010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3320
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.guided.160"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            213..929
                     /locus_tag="MIV85_003924"
     CDS             213..929
                     /locus_tag="MIV85_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBY2963178.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            904..3237
                     /locus_tag="MIV85_003925"
     CDS             904..3237
                     /locus_tag="MIV85_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBY2963179.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKAVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
BASE COUNT         1394 a          295 c          567 g         1064 t
ORIGIN      
        1 gtaatatctt aagtttttaa ttttaatatt aagtatataa aacaaaatga aaaaatatta
       61 aatttaaact agaaggaggt ttctaagatg gacattaaat acaaataacc agaacaaaag
      121 atataaatat atatataaat ggaaaaactt ctatcatatt gtataatcat atatgtaaag
      181 aaaatttata aattaatata aaggagatta gaatgaattc atataatatt ttggtggtag
      241 aagatgaaaa ggagatagca gatgctatag aaatatatct attaaatcaa ggatataatg
      301 tttttaaggg atacaatgga ttagaaggtc ttaaggttat agaaaaccaa gaaatacatt
      361 tagctatagt tgatataatg atgcctaaaa tggatggtat aacacttaca atgaagctta
      421 gagaaaacta taattttcca gtaataatgc tatctgcaaa atcagaagaa gttgacaaaa
      481 taatggggct taatatagga gcagacgatt atgtaacaaa accttttaag ccattagaac
      541 tattggctag agttaattca caacttagaa ggtacactaa gtatctaaac atggttggaa
      601 ataaagagca aaaggtagaa agtgacgata gtgtgtttgc aataggcgga ttagaattaa
      661 atgaaaatac aaaagaagtt agtattgatg gaaagtatat aaaaacaact cctatagaat
      721 ttaaaatact aagtttactt atgagaaatg caggaagagt tttttctgct gatgaaatat
      781 atgaaagagt ttggaatgag aatgctgtaa atacagatac agttatggta catgtgagga
      841 atataaggga aaagatagaa attgacccaa aaaatcctaa atatttaaag gtggtgtggg
      901 gtgttggata caaaattgaa aaaatttaaa gataaatata tagttactat tatagttttt
      961 atacttatgt tatcagcatc attaggtatg attagtcaat attctactat acaagcaagt
     1021 gctaaaggtg gagcagagaa tccatttgaa caggaaagct ttgtagatag tatatataaa
     1081 ggaagttatg ttttatatca taatatgaag gaagaacaag aaggtaagat gatacaacca
     1141 tcaaagctat ttatcaatga agaaactatg aactatataa aaaatgtaag taaagaaaaa
     1201 gatacttatg atggttcaga aacttattat acagatgata gtattaatgc agattttaat
     1261 gaaaactttg aaaattggga gcatttcatt aaagcgtcag gaaagaattt aaagtactat
     1321 ttagttgata aagaaagcaa ttttgaattt tttaatgata ataaagaatt aggagtactt
     1381 gatacaacaa aaaatgatgc ttcaaaagaa aattctaatg aaaatcagtc aaaaaataca
     1441 gaaatgaatg atgaggaaag acaaaagcag attacagata taaaagaaaa ctatagattc
     1501 tacgttgtaa tgaattttga taaagatgga aaagtaaata ttgtggattc ttatggagta
     1561 aatcaaaaaa ttattaatca aatgttgtta tctaaagcaa gagaagattt aatggataca
     1621 agtttaggag gaaattcaat ttcatataag ttatctccaa taaaaaatat aacattagta
     1681 tatgctgtac ctaaagtaat aagtaaaggt gatagtgtag agtatggtta tggaaatact
     1741 tattttgatg atggtataat ttcatatata agcaatgtag aaaataattc ttattataag
     1801 atttctggaa tgattttaaa aattatatta gctatagttg ttattgtagc tttagcattc
     1861 ccatatagaa aatctaaaga gttgctagga tttgatacat tatcaagaat accgttagag
     1921 atactcttta ttgctcttgc tattatacag gggcttgtag atttatatcc tactgttata
     1981 ataagtaata ccttgagtgg gaattatgta gagtacctta taaacaatga cataagtgct
     2041 aaaatggcta gtatattggt aagtttaatg aatttaactt attggtttgt aatattctca
     2101 ataatatttg tatttataat acttttaaaa cacattttaa atgttggaat aagagagtat
     2161 tttacaaaac atactgtgac aggaatgttt tttgtatggt taaaaaaagc aggaaaagca
     2221 gttattaatc aaattagaac aataaatctg aaagaaaagc caaataaaac tatagttaca
     2281 attttgggaa taaatttatt gattatagtt ataatgtgta gtatgtggtt ctttggaata
     2341 atactcgcat taatatattc agtagtatta tttaagatac tgtcagatta ctctaaaaag
     2401 acaatatatg aatataatca acttttagat gttacaaaga aaatttcaga tggaaactta
     2461 gatgtaaata tggaaaaaga tttaggattt tttaatccta taaaagatga attaggaaat
     2521 attcaaactg gatttaaaaa agctgttgac gaagaggtta agagtcaaaa gatgaaaaca
     2581 gagcttatat caaatgtatc acatgactta aaaacacctc taacatctat aatcacttat
     2641 atagatttat taaaagatga aagtataaca gatgaaaatc gtaagttgta tattgataca
     2701 ttagacagaa agtcacaaag attgcaacat ctaatagaag atttgtttga agtaagcaag
     2761 gcaaatagtg gagatgttta tttgaatata gtaaatgtgg atattgtatc tctaatgaag
     2821 cagacacttt tagaattaga tgacaaactt gcagattcat ctctaatagt aaagaataac
     2881 ttttctaatg aaaaaataat attaccatta gatagtcagc gtacatttag agtatttgaa
     2941 aatcttataa taaatataag caaatatgca atgccaaatt caagagtgta tattgatatt
     3001 ttagaaacag ataataaagt aaatattatg cttaaaaata tgtctgcatc tgagattgat
     3061 tttagtgtag atgatataat ggagagattt gtaagaggag ataaatcacg taacacagaa
     3121 ggttctggtc ttggtttagc gatagcaaaa agttttatag aattacaggg tggtaagatg
     3181 aatataagtg tggatggtga tttattcaaa gttacaatta cttttaacaa aaattagatt
     3241 agacttcttt aataattata aagtctatag aataaaagaa tctggaaata tttatgtgta
     3301 ttctttaaat aaaaatttat
//
LOCUS       DAGQVA010000225         2448 bp    DNA     linear   BCT 16-FEB-2022
DEFINITION  TPA_asm: Clostridioides difficile strain RT14 isolate 15.7922329
            SAMN25516874-rid13959193.guided.172, whole genome shotgun sequence.
ACCESSION   DAGQVA010000225 DAGQVA010000000
VERSION     DAGQVA010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN25516874
            Sequence Read Archive: SRR17631300
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-FEB-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001250421.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001250421.1
            Genome Coverage       :: 53x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/16/2022 18:21:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,928
            CDSs (total)                      :: 3,847
            Genes (coding)                    :: 3,800
            CDSs (with protein)               :: 3,800
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 18 of 47
            Pseudo Genes (incomplete)         :: 28 of 47
            Pseudo Genes (internal stop)      :: 12 of 47
            Pseudo Genes (multiple problems)  :: 8 of 47
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2448
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN25516874-rid13959193.guided.172"
                     /strain="RT14"
                     /isolate="15.7922329"
                     /isolation_source="Human infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom"
                     /collection_date="2015-06-01"
                     /collected_by="ModMedMicOxford"
     gene            <1..178
                     /locus_tag="MIV85_003926"
     CDS             <1..178
                     /locus_tag="MIV85_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBY2963180.1"
                     /translation="DKEISSKDEGQRIYKKLFMKDGSLVGAILINDLSCTVKLIRLIS
                     EKGDFEDIMKADIL"
     gene            612..1313
                     /locus_tag="MIV85_003927"
     CDS             612..1313
                     /locus_tag="MIV85_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBY2963181.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            1363..2445
                     /locus_tag="MIV85_003928"
     CDS             1363..2445
                     /locus_tag="MIV85_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBY2963182.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
BASE COUNT          911 a          264 c          421 g          852 t
ORIGIN      
        1 tgataaagaa atttcatcaa aagatgaagg tcaaagaata tataaaaaat tatttatgaa
       61 agatggttca ttagttggag ctatacttat aaatgattta agctgtactg ttaaattgat
      121 aagattaata tctgaaaaag gtgattttga ggatattatg aaggctgata tactataatt
      181 taaatacatt aaaataaaaa ggagttgtct caaaattgat ttttttctaa tcaaatttta
      241 aattcaactc cttttttgaa tttttatata aaataacatg gaaattttag taatgtctgt
      301 ggttacatac ataggtttaa ttgtttttta tatggattgt ctctggtata ataaattgaa
      361 ttgtgtttga ctgatagata tttttattga aagttaatac ctgttatgcg ataataagga
      421 cgtgttaggg gagtttttat aataacaatt aatctcagtt tttgtgttcc aatagtagca
      481 tcaacacatt ctgatgtagt agttcttttc ttataaaaat tagttacaaa tatgcttgta
      541 attatttgat atgtaaattt accaatatta taaatgatga cctcgataat aaggagagtg
      601 aaaaataatc tatgaacgaa aatattttga ttgtggatga tgaaaaagaa atagcagatt
      661 taattgaagt atatttaaaa aatgaaggtt ttacagtata caagttttat acaggtaagg
      721 aagctctaga atgtattgaa tctaaaaatt tggatatggc tattttagat attatgcttc
      781 ctgatattga tggatttcat atttgccaga aaattcgaga aaaatactat tatcctatca
      841 ttatgttaac agctaaaatt gaagatatag acaagataat gggtttaacc ataggtgctg
      901 atgattatat aacaaagcca tttaaccctt tggaagttgt tgcaagagta aagacacaat
      961 taagaagata tatgcgatat aataattctt atgaacaaca gtcgataatt gttaatgagt
     1021 atgatattaa aggattgatt atcaataaag aaacacataa atgtagttta tttgggaaag
     1081 aagtagcatt aacaccgatt gaattttcta ttctttggta tttatgtgaa catcaaggaa
     1141 aagtggttcc ttctgaagaa ttgtttgaag ctgtatgggg agaaaaatat cttgataata
     1201 ataacacagt tatggctcat atagggcgat tacgtgaaaa aattcatgaa ccttctaaaa
     1261 acccgaaatt tataaaaact gtatggggag taggttatac aattgaaaag taaaaatatt
     1321 aaagtcaatc ctgactttac tcaagtgaga aataaaattt ttatgagaac agctttaatg
     1381 gcatttatag ccattatttt catatggatt ttatattctt ttatattgta tggtaagttt
     1441 tctatctgga tagtatcatt ctttgaaaat gcttttcgta tggaatataa agctgcattg
     1501 aatttatatc agcagatttt ccgtaatagc atggagctct tcatgatact agctatggtg
     1561 attgtgtttt ttataatatt ccgggtttat ttaaattggt ttacaaaata ttttagtgaa
     1621 ataaatcaag gtattgactc tcttatcaaa gaagatgttg gagaagtggc tttatctcca
     1681 gagttattgg caatagaaaa gaaaataaac tcaattaaac atatacttga acaacgtaaa
     1741 tttgagacac aaatggcaga acaacgtaag aatgaactta ttgtttatct tgcacatgat
     1801 ttaaaaacac cacttacatc agttataggg tatctgacac tacttcgaga tgaaagtcag
     1861 atttctgaag aactgcgaaa aaaatattta tctatttcgt tggataaggc agagcgtctt
     1921 gaagatttaa ttaatgaatt ctttgaaatt acaaggttta atttatcaaa tatatcactt
     1981 gaatacagta cagtaagctt aactcgtatg cttgaacaac taacatatga gtttaaacct
     2041 actttgatga gtaagaattt aaaatataca ctgaatgtta caccaaatat gatgataagg
     2101 tgtgatgtta ataaaatgca acgtgtattt gataacttat tacgaaatgc tgtttattat
     2161 agttttgaag atactactat tgaaataaca gctgtacagg aggatgatta tataaagctt
     2221 aaatttataa atcatagcaa tacgattcca gaggaaaaac ttgagcgtat ttttgaacaa
     2281 ttttacaggt tggatacatc tcgtaattca aacagtggta gagctgggtt gggacttgct
     2341 atagctaaag aaatagtgga gcttcataac gggacaataa cagctcatag cgagaacaat
     2401 ataattatct ttaaggttat tattccgatt gtaggaaatt tgtaagaa
//
